# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- SNF2_N PF00176.23 EER22853.1 - 4.2e-15 55.3 0.1 7.5e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER22853.1 - 0.0007 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vhr1 PF04001.13 EER22853.1 - 0.063 13.6 0.4 0.2 12.0 0.4 1.8 1 0 0 1 1 1 0 Transcription factor Vhr1 Dynamin_N PF00350.23 EER22855.1 - 1.5e-33 116.2 0.3 4.5e-33 114.7 0.1 1.9 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EER22855.1 - 2.8e-22 79.3 0.1 3e-21 75.9 0.1 2.4 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EER22855.1 - 1.9e-06 27.9 0.0 5.7e-05 23.2 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EER22855.1 - 0.00083 19.2 1.3 0.0011 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EER22855.1 - 0.0027 17.4 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EER22855.1 - 0.0032 18.0 0.1 0.03 14.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain PRK PF00485.18 EER22855.1 - 0.026 14.3 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Trp_dioxygenase PF03301.13 EER22855.1 - 0.038 13.3 0.7 0.063 12.6 0.7 1.2 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase GED PF02212.18 EER22855.1 - 0.041 14.0 0.6 0.24 11.5 0.1 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain DUF2505 PF10698.9 EER22855.1 - 0.061 13.4 0.1 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) AAA_16 PF13191.6 EER22855.1 - 0.084 13.2 0.6 0.45 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain DUF3435 PF11917.8 EER22856.1 - 5.1e-66 223.3 0.1 4.6e-58 197.1 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) IMS PF00817.20 EER22857.1 - 1.5e-43 148.4 0.8 3.1e-43 147.4 0.8 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EER22857.1 - 7.5e-17 62.1 1.2 1.4e-16 61.2 0.3 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EER22857.1 - 1.4e-06 28.2 0.0 4.5e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Vps36-NZF-N PF16988.5 EER22857.1 - 0.045 13.1 0.5 0.11 11.9 0.5 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain BAF PF02961.14 EER22857.1 - 0.07 13.6 0.0 0.49 10.9 0.0 2.2 2 0 0 2 2 2 0 Barrier to autointegration factor NIBRIN_BRCT_II PF16508.5 EER22858.1 - 4.1e-34 117.4 0.0 9e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EER22858.1 - 3e-05 24.3 0.2 6.7e-05 23.2 0.2 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.26 EER22858.1 - 0.0062 16.9 0.1 0.034 14.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EER22858.1 - 0.019 14.8 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Sugar_tr PF00083.24 EER22859.1 - 1.9e-75 254.5 25.5 2.2e-75 254.3 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER22859.1 - 4.5e-18 65.3 57.1 5.2e-14 51.9 25.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 EER22859.1 - 1.5 7.0 9.6 2.4 6.3 9.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cyclase PF04199.13 EER22860.1 - 3.4e-10 40.3 0.3 4.8e-10 39.8 0.3 1.3 1 0 0 1 1 1 1 Putative cyclase Acetyltransf_1 PF00583.25 EER22861.1 - 5.2e-10 39.6 0.0 6.7e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER22861.1 - 2.9e-09 37.2 0.2 4.3e-09 36.7 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER22861.1 - 1.1e-08 35.0 0.0 2.8e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER22861.1 - 3.6e-05 23.8 0.0 6.2e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER22861.1 - 0.011 15.7 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Ferritin_2 PF13668.6 EER22862.1 - 4.6e-06 26.9 0.0 7.2e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.24 EER22863.1 - 1.4e-21 76.9 24.9 4.6e-13 48.9 7.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter SR-25 PF10500.9 EER22864.1 - 0.25 10.9 6.5 0.44 10.1 6.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AMP-binding PF00501.28 EER22865.1 - 7.7e-75 252.1 0.0 9.5e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER22865.1 - 8.3e-13 49.1 0.7 1.6e-12 48.2 0.7 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EER22866.1 - 1.3e-38 132.9 25.7 2e-38 132.2 24.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily CoA_binding_2 PF13380.6 EER22867.1 - 4.6e-29 101.3 0.0 5.2e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Rad4 PF03835.15 EER22869.1 - 4e-30 104.4 0.6 8.4e-30 103.4 0.0 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EER22869.1 - 3.7e-28 97.7 0.2 7.1e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 EER22869.1 - 1.1e-15 58.3 0.7 3.4e-15 56.7 0.1 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 EER22869.1 - 5.1e-15 55.1 0.0 1.2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 EER22869.1 - 0.02 15.3 0.0 0.058 13.8 0.0 1.8 1 0 0 1 1 1 0 Transglutaminase-like superfamily HIT PF01230.23 EER22870.1 - 4.7e-24 85.0 0.2 8.8e-24 84.1 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EER22870.1 - 0.00011 22.7 0.0 0.00019 21.8 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EER22870.1 - 0.094 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 HD_3 PF13023.6 EER22871.1 - 2.4e-51 173.9 0.2 3.1e-51 173.6 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EER22871.1 - 9.6e-14 51.5 0.2 1.2e-13 51.2 0.2 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EER22871.1 - 0.028 14.6 0.1 0.086 13.1 0.1 1.8 1 1 0 1 1 1 0 HD domain HAUS6_N PF14661.6 EER22872.1 - 2.8e-15 56.5 1.5 7.4e-15 55.2 0.1 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus APG6_N PF17675.1 EER22872.1 - 4.2 7.9 6.4 37 4.9 4.9 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region cobW PF02492.19 EER22873.1 - 8.3e-48 162.3 0.0 1.1e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EER22873.1 - 4.8e-05 23.3 0.1 0.39 10.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Septin PF00735.18 EER22873.1 - 0.0023 17.3 0.1 1.2 8.4 0.0 2.1 2 0 0 2 2 2 2 Septin AAA_18 PF13238.6 EER22873.1 - 0.0069 16.9 0.0 0.051 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EER22873.1 - 0.0076 16.7 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 EER22873.1 - 0.0081 16.2 0.0 0.022 14.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EER22873.1 - 0.013 15.8 0.1 0.099 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EER22873.1 - 0.014 14.9 0.0 2.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EER22873.1 - 0.015 15.1 0.0 0.029 14.1 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EER22873.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MeaB PF03308.16 EER22873.1 - 0.023 13.7 0.2 3.3 6.6 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EER22873.1 - 0.035 13.2 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EER22873.1 - 0.037 14.5 0.0 0.093 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EER22873.1 - 0.047 14.2 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter CobW_C PF07683.14 EER22873.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain CDCA PF18484.1 EER22873.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat AAA_14 PF13173.6 EER22873.1 - 0.088 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EER22873.1 - 0.094 12.4 0.0 0.82 9.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EER22873.1 - 0.11 12.2 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EER22873.1 - 0.13 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EER22873.1 - 0.19 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mob1_phocein PF03637.17 EER22874.1 - 2.1e-24 86.4 0.1 3.3e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 EER22874.1 - 0.25 11.6 4.7 0.58 10.5 4.7 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Pkinase PF00069.25 EER22875.1 - 1.3e-11 44.4 0.0 3.7e-10 39.6 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER22875.1 - 2.6e-08 33.5 0.0 3.8e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2064 PF09837.9 EER22875.1 - 0.048 13.5 0.0 3.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) Kinase-like PF14531.6 EER22875.1 - 0.13 11.5 0.0 0.35 10.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Lon_C PF05362.13 EER22876.1 - 6.6e-62 208.7 0.0 1.5e-61 207.5 0.0 1.7 2 0 0 2 2 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EER22876.1 - 2.8e-35 122.1 0.3 2.8e-35 122.1 0.3 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EER22876.1 - 5.5e-22 78.6 0.0 1.3e-21 77.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EER22876.1 - 1.3e-06 28.5 0.0 2.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EER22876.1 - 2.6e-06 27.6 0.0 7.6e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 EER22876.1 - 2.3e-05 24.2 0.0 6.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 EER22876.1 - 3.1e-05 23.0 0.2 7.5e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_22 PF13401.6 EER22876.1 - 3.8e-05 24.0 0.0 0.00049 20.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EER22876.1 - 7.1e-05 22.6 0.4 0.00066 19.5 0.0 2.8 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EER22876.1 - 0.00026 21.4 0.8 0.002 18.5 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_18 PF13238.6 EER22876.1 - 0.01 16.4 1.1 0.074 13.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF4276 PF14103.6 EER22876.1 - 0.016 15.4 0.2 0.049 13.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) AAA_14 PF13173.6 EER22876.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNTTIP1_dimer PF18192.1 EER22876.1 - 0.023 15.1 4.3 2.7 8.4 0.4 3.1 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain AAA_30 PF13604.6 EER22876.1 - 0.026 14.2 0.3 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EER22876.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EER22876.1 - 0.047 13.6 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 EER22876.1 - 0.069 13.1 0.3 1.4 8.8 0.0 2.9 2 1 1 3 3 3 0 NTPase RNA_helicase PF00910.22 EER22876.1 - 0.073 13.5 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase SKI PF01202.22 EER22876.1 - 0.097 12.8 0.5 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase AAA_7 PF12775.7 EER22876.1 - 0.14 11.7 0.5 0.25 10.9 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region ClpB_D2-small PF10431.9 EER22876.1 - 0.82 9.8 7.0 0.1 12.7 0.5 2.7 3 0 0 3 3 3 0 C-terminal, D2-small domain, of ClpB protein DUF445 PF04286.12 EER22876.1 - 0.9 9.3 8.7 0.79 9.5 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF445) ABC_tran PF00005.27 EER22876.1 - 1.8 9.1 5.3 0.83 10.2 0.0 2.8 3 0 0 3 3 2 0 ABC transporter AAA_23 PF13476.6 EER22876.1 - 5.9 7.3 11.9 4.3 7.8 1.0 3.1 2 1 0 2 2 2 0 AAA domain Yuri_gagarin PF15934.5 EER22876.1 - 8.2 6.2 11.0 0.9 9.3 5.5 2.0 2 0 0 2 2 2 0 Yuri gagarin DnaJ_C PF01556.18 EER22877.1 - 1.1e-37 129.5 0.0 1.4e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EER22877.1 - 2.2e-23 82.1 2.8 2.2e-23 82.1 2.8 2.2 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EER22877.1 - 1.6e-09 37.9 19.4 1.6e-09 37.9 19.4 2.3 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 EER22877.1 - 1.3 9.0 19.1 0.43 10.6 4.5 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein BRO1 PF03097.18 EER22878.1 - 2.2e-129 431.7 1.2 2.6e-129 431.5 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EER22878.1 - 1.2e-81 274.3 12.5 2.2e-81 273.4 12.5 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF4564 PF15169.6 EER22878.1 - 0.13 12.0 1.5 0.3 10.8 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4564) DUF2383 PF09537.10 EER22878.1 - 0.14 12.5 3.0 0.79 10.1 0.3 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF2383) GTA_holin_3TM PF11351.8 EER22878.1 - 0.27 11.8 0.8 1.5 9.4 0.0 2.6 3 0 0 3 3 3 0 Holin of 3TMs, for gene-transfer release SAP30_Sin3_bdg PF13867.6 EER22879.1 - 7.8e-09 35.7 0.1 4.7e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-H2C2_2 PF13465.6 EER22880.1 - 1.8e-08 34.4 18.6 2.7e-05 24.4 3.0 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EER22880.1 - 2.7e-05 24.4 14.0 0.00082 19.7 4.5 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER22880.1 - 0.008 16.9 18.7 0.057 14.3 3.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EER22880.1 - 0.016 15.2 1.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER22880.1 - 0.031 14.6 1.4 0.13 12.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EER22880.1 - 0.047 14.3 1.1 0.13 12.9 0.1 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 EER22880.1 - 7.9 6.3 14.2 3.6 7.4 0.2 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain MOSC PF03473.17 EER22881.1 - 1.7e-22 79.8 0.0 2.8e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EER22881.1 - 1.1e-06 28.6 0.0 2.6e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Rad51 PF08423.11 EER22882.1 - 1.6e-11 44.0 0.0 3.5e-10 39.6 0.0 2.2 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EER22882.1 - 1.7e-06 27.7 0.5 0.00045 19.8 0.2 2.7 2 1 0 2 2 2 1 AAA domain RecA PF00154.21 EER22882.1 - 2.4e-05 23.9 0.0 7.5e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 recA bacterial DNA recombination protein IstB_IS21 PF01695.17 EER22882.1 - 0.0051 16.6 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein CbiA PF01656.23 EER22882.1 - 0.0075 16.3 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase PF06745.13 EER22882.1 - 0.0078 15.6 0.0 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 KaiC CLP1_P PF16575.5 EER22882.1 - 0.013 15.4 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EER22882.1 - 0.021 14.8 0.0 0.058 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EER22882.1 - 0.022 14.7 0.0 0.042 13.8 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DnaB_C PF03796.15 EER22882.1 - 0.029 13.7 0.1 0.37 10.1 0.0 2.2 2 1 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EER22882.1 - 0.053 13.9 0.2 0.16 12.4 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EER22882.1 - 0.053 13.8 0.0 0.28 11.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain PhoH PF02562.16 EER22882.1 - 0.081 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 EER22882.1 - 0.098 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 EER22882.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain FA_desaturase PF00487.24 EER22883.1 - 1.2e-17 64.7 12.8 1.2e-17 64.7 12.8 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EER22883.1 - 1.3e-16 60.5 0.0 3.2e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF1189 PF06691.11 EER22883.1 - 0.26 10.8 0.2 0.63 9.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Peptidase_M3 PF01432.20 EER22884.1 - 9.9e-163 542.6 0.1 1.5e-162 542.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peroxin-3 PF04882.12 EER22884.1 - 0.13 11.3 0.3 0.19 10.7 0.3 1.2 1 0 0 1 1 1 0 Peroxin-3 YABBY PF04690.13 EER22885.1 - 0.024 15.2 0.1 1.8 9.1 0.3 2.2 2 0 0 2 2 2 0 YABBY protein DUF3408 PF11888.8 EER22885.1 - 0.061 13.5 4.7 0.13 12.4 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CDC45 PF02724.14 EER22885.1 - 0.34 9.2 5.8 0.36 9.1 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EER22885.1 - 1 8.1 3.1 1.3 7.7 3.1 1.1 1 0 0 1 1 1 0 Presenilin EF-hand_7 PF13499.6 EER22886.1 - 7.5e-13 48.7 0.2 3.4e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EER22886.1 - 4.9e-11 42.8 0.0 2.3e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EER22886.1 - 1.8e-09 36.8 1.1 0.017 15.0 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EER22886.1 - 3.7e-09 35.5 0.2 0.036 13.6 0.0 3.8 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EER22886.1 - 1.9e-06 27.6 0.1 7e-05 22.6 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 EER22886.1 - 0.086 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Fungal_trans PF04082.18 EER22887.1 - 7e-70 235.1 0.0 1.1e-69 234.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EER22887.1 - 2.1e-05 24.7 13.3 0.0025 18.1 2.9 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER22887.1 - 0.3 11.6 10.3 0.3 11.6 2.7 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER22887.1 - 4.9 8.3 18.5 0.21 12.5 2.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Xpo1 PF08389.12 EER22888.1 - 2.1e-27 96.0 1.4 8.4e-27 94.1 0.3 2.7 2 0 0 2 2 2 1 Exportin 1-like protein IBN_N PF03810.19 EER22888.1 - 5.9e-06 26.1 0.0 1.7e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain HEAT PF02985.22 EER22888.1 - 0.0014 18.7 0.0 32 5.2 0.0 4.7 3 0 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 EER22888.1 - 0.0017 18.7 1.0 0.043 14.2 0.0 3.8 5 0 0 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 EER22888.1 - 0.003 18.0 1.4 0.12 12.9 0.0 4.5 6 0 0 6 6 6 1 HEAT-like repeat Importin_rep_3 PF18806.1 EER22888.1 - 0.026 14.5 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 Importin 13 repeat Death PF00531.22 EER22888.1 - 0.076 13.2 0.4 0.55 10.4 0.1 2.4 2 0 0 2 2 2 0 Death domain DUF3385 PF11865.8 EER22888.1 - 0.16 11.9 1.3 3.8 7.4 0.1 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) LSM PF01423.22 EER22889.1 - 9e-15 54.1 0.1 1e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EER22889.1 - 0.0021 17.6 0.1 0.0035 17.0 0.1 1.3 1 0 0 1 1 1 1 Hfq protein PhnA PF03831.14 EER22889.1 - 0.11 12.4 0.0 2.1 8.3 0.0 2.2 2 0 0 2 2 2 0 PhnA domain 5-FTHF_cyc-lig PF01812.20 EER22890.1 - 7.6e-20 71.6 0.0 2.2e-17 63.5 0.0 2.4 2 1 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.9 EER22891.1 - 1.7e-95 318.5 0.1 1.9e-95 318.3 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.10 EER22892.1 - 7.7e-22 77.9 1.1 9e-22 77.7 1.1 1.1 1 0 0 1 1 1 1 Yqey-like protein Nucleoporin_N PF08801.11 EER22893.1 - 2.8e-90 303.1 0.1 5.5e-90 302.2 0.1 1.5 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EER22893.1 - 2.3e-51 175.3 3.9 8.6e-51 173.4 2.1 2.0 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal NAT PF04768.13 EER22894.1 - 2e-50 170.8 0.0 5.9e-50 169.2 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Arv1 PF04161.13 EER22895.1 - 1.6e-60 204.9 0.3 4e-59 200.3 0.3 2.2 1 1 0 1 1 1 1 Arv1-like family ATP_synt_H PF05493.13 EER22896.1 - 3.6e-24 85.0 2.3 4.1e-24 84.8 2.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Pox_A14 PF05767.12 EER22896.1 - 0.019 15.1 0.3 0.021 15.0 0.3 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF1129 PF06570.11 EER22896.1 - 0.025 14.1 0.6 0.029 13.8 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF4131 PF13567.6 EER22896.1 - 0.11 12.2 1.8 0.12 12.1 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Phage_holin_2_3 PF16080.5 EER22896.1 - 0.13 12.1 1.9 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin family HP1 YfhO PF09586.10 EER22896.1 - 0.22 9.7 0.8 0.24 9.6 0.8 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Dabb PF07876.12 EER22897.1 - 1.3e-16 61.0 0.2 1.5e-16 60.8 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Nore1-SARAH PF16517.5 EER22897.1 - 0.073 13.0 0.2 0.12 12.3 0.2 1.3 1 0 0 1 1 1 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain Tudor_FRX1 PF18336.1 EER22897.1 - 0.097 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain BAR_2 PF10455.9 EER22898.1 - 1.6e-63 214.6 0.2 2.2e-63 214.1 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EER22898.1 - 9.7e-21 74.5 4.7 2.7e-19 69.7 4.7 2.0 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EER22898.1 - 0.00036 20.3 0.9 0.033 13.9 0.0 2.3 2 0 0 2 2 2 2 BAR domain of APPL family ApoLp-III PF07464.11 EER22898.1 - 0.021 14.9 1.1 0.22 11.6 0.1 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Arfaptin PF06456.13 EER22898.1 - 0.039 13.5 1.4 0.11 12.0 0.3 2.2 2 1 0 2 2 2 0 Arfaptin-like domain APH PF01636.23 EER22899.1 - 1.2e-05 25.3 4.7 3.8e-05 23.7 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EER22899.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EER22899.1 - 0.00018 21.0 0.0 0.00046 19.6 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EER22899.1 - 0.008 15.0 0.5 0.29 9.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Alanine_zipper PF11839.8 EER22899.1 - 0.39 11.1 20.3 0.96 9.9 20.3 1.6 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein DUF1151 PF06625.11 EER22899.1 - 7.4 6.6 10.4 19 5.2 10.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Borrelia_P83 PF05262.11 EER22899.1 - 8 4.8 8.6 15 4.0 8.6 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur PF00064.18 EER22900.1 - 0.25 10.1 0.1 1.5 7.5 0.0 1.9 2 0 0 2 2 2 0 Neuraminidase Methyltransf_8 PF05148.15 EER22902.1 - 1e-51 175.9 0.1 1.7e-49 168.6 0.0 2.8 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EER22902.1 - 2.4e-06 28.1 0.0 1.6e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER22902.1 - 0.00012 22.7 0.0 0.013 16.2 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EER22902.1 - 1.3 9.0 0.0 1.3 9.0 0.0 3.0 3 1 0 3 3 3 0 Methyltransferase domain Proteasome PF00227.26 EER22903.1 - 6.7e-57 192.1 0.1 8.5e-57 191.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EER22903.1 - 1.5e-12 46.9 0.2 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 EER22904.1 - 2.2e-66 224.6 0.0 3.6e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EER22904.1 - 2.1e-61 208.1 3.5 3.6e-61 207.3 3.5 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal KH_8 PF17903.1 EER22905.1 - 1.3e-30 105.3 0.0 2.9e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain Methyltransf_23 PF13489.6 EER22906.1 - 6.7e-12 45.6 0.0 8.8e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER22906.1 - 1.2e-11 45.1 0.0 2.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER22906.1 - 1.5e-11 44.8 0.0 4.2e-11 43.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER22906.1 - 3.4e-07 30.9 0.0 7.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER22906.1 - 2.7e-05 24.0 0.0 0.00013 21.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EER22906.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 EER22906.1 - 0.022 14.9 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EER22906.1 - 0.023 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EER22906.1 - 0.043 13.1 0.0 0.087 12.1 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain DUF4646 PF15496.6 EER22906.1 - 0.07 13.7 0.0 0.12 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Ubie_methyltran PF01209.18 EER22906.1 - 0.16 11.3 0.0 0.75 9.1 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short PF00106.25 EER22907.1 - 3.7e-40 137.5 0.0 5.2e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER22907.1 - 6.3e-25 88.1 0.0 8.5e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER22907.1 - 3e-05 24.0 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EER22907.1 - 0.0002 20.6 0.1 0.00034 19.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EER22907.1 - 0.0055 16.2 0.0 0.0076 15.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EER22907.1 - 0.012 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EER22907.1 - 0.031 14.5 0.1 0.081 13.2 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Erg28 PF03694.13 EER22908.1 - 8.3e-42 142.0 2.1 9.9e-42 141.8 2.1 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_tr_C PF02744.17 EER22909.1 - 2.2e-59 199.9 0.3 4.9e-59 198.8 0.1 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 EER22909.1 - 5.3e-53 180.2 0.2 2e-51 175.0 0.1 2.6 2 1 1 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 EER22909.1 - 4.8e-07 30.4 0.0 1.1e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EER22909.1 - 0.00021 21.8 0.0 0.00044 20.7 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Fungal_trans_2 PF11951.8 EER22910.1 - 9.3e-24 83.9 0.0 3.6e-17 62.3 0.1 3.7 4 0 0 4 4 4 3 Fungal specific transcription factor domain Zn_clus PF00172.18 EER22910.1 - 4.6e-07 29.9 11.9 8.8e-07 29.0 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EER22910.1 - 0.042 12.9 0.1 0.076 12.0 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Asp_protease PF09668.10 EER22911.1 - 5.8e-59 197.3 0.1 8.7e-59 196.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EER22911.1 - 2.4e-22 79.3 0.0 4.9e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EER22911.1 - 2.7e-10 40.7 0.1 1.4e-09 38.4 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 EER22911.1 - 5.1e-08 32.5 0.0 9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EER22911.1 - 2.7e-07 30.4 0.0 5.3e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.6 EER22911.1 - 0.00044 20.0 0.0 0.00096 18.9 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain RVP PF00077.20 EER22911.1 - 0.0037 17.6 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP_2 PF08284.11 EER22911.1 - 0.0037 17.0 0.0 0.0072 16.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UN_NPL4 PF11543.8 EER22911.1 - 0.0046 17.4 0.0 0.0091 16.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 NAD_binding_7 PF13241.6 EER22911.1 - 0.051 14.0 0.1 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Ubiquitin_4 PF18036.1 EER22911.1 - 0.11 12.6 0.0 3.2 7.8 0.0 2.5 1 1 0 1 1 1 0 Ubiquitin-like domain Acetyltransf_10 PF13673.7 EER22912.1 - 1e-13 51.4 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER22912.1 - 3.6e-13 49.8 0.0 6.1e-13 49.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER22912.1 - 1.8e-09 37.9 0.0 3.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER22912.1 - 0.00018 21.4 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EER22912.1 - 0.00039 20.5 0.0 0.00078 19.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EER22912.1 - 0.0011 19.1 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NOG1_N PF17835.1 EER22913.1 - 7.7e-49 165.7 1.8 8.1e-49 165.7 0.1 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EER22913.1 - 6e-28 96.6 3.2 1.4e-27 95.4 3.2 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EER22913.1 - 2.1e-26 91.5 0.3 4.1e-26 90.5 0.3 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EER22913.1 - 6.5e-16 58.4 0.0 1.8e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EER22913.1 - 5.5e-08 32.5 0.0 1.6e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EER22913.1 - 0.00077 19.6 0.8 0.98 9.5 0.0 2.9 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EER22913.1 - 0.0011 18.9 1.0 0.65 9.9 0.0 3.5 3 2 1 4 4 4 1 RsgA GTPase AAA_23 PF13476.6 EER22913.1 - 0.046 14.2 0.5 2.3 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EER22913.1 - 0.06 13.6 0.0 0.47 10.7 0.0 2.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EER22913.1 - 0.18 12.1 1.7 0.45 10.9 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AATase PF07247.12 EER22914.1 - 3.3e-10 39.1 0.0 4.9e-09 35.3 0.0 2.3 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EER22914.1 - 8.4e-05 21.4 0.7 0.26 9.9 0.1 2.2 2 0 0 2 2 2 2 Condensation domain DUF3791 PF12668.7 EER22914.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) E1_DerP2_DerF2 PF02221.15 EER22915.1 - 1.7e-28 99.7 0.1 2e-28 99.5 0.1 1.1 1 0 0 1 1 1 1 ML domain Big_9 PF17963.1 EER22915.1 - 0.0026 18.5 0.0 0.0083 16.8 0.0 1.7 2 0 0 2 2 2 1 Bacterial Ig domain Alph_Pro_TM PF09608.10 EER22915.1 - 0.0076 16.1 0.0 0.0093 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) Wzt_C PF14524.6 EER22915.1 - 0.069 13.2 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Wzt C-terminal domain ATP-synt_F PF01990.17 EER22916.1 - 3.3e-33 113.9 0.1 3.8e-33 113.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.9 EER22917.1 - 7.5e-35 119.3 0.3 2.4e-34 117.8 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) MTHFR PF02219.17 EER22919.1 - 9e-116 386.2 0.0 1.3e-115 385.7 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Pribosyltran PF00156.27 EER22920.1 - 2.2e-15 56.5 0.1 3.2e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_transf_5 PF08323.11 EER22922.1 - 3.7e-13 49.7 0.0 7.4e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.24 EER22922.1 - 2.7e-11 43.6 0.1 2.1e-10 40.7 0.2 2.1 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 EER22922.1 - 5.6e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EER22922.1 - 0.00024 21.2 0.0 0.00058 19.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EER22922.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Aconitase PF00330.20 EER22923.1 - 7.9e-166 552.6 0.0 9.5e-166 552.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EER22923.1 - 2e-39 134.9 0.0 3.8e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EER22923.1 - 0.011 14.5 0.1 0.038 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF521) Glycos_transf_4 PF00953.21 EER22924.1 - 2.9e-35 121.6 11.5 2.9e-35 121.6 11.5 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2070 PF09843.9 EER22924.1 - 9.5 4.4 9.3 15 3.7 9.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) WD40 PF00400.32 EER22925.1 - 1.2e-10 41.8 6.8 0.0006 20.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER22925.1 - 0.0019 18.5 0.1 0.39 11.0 0.0 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain peroxidase PF00141.23 EER22926.1 - 1.5e-49 168.7 0.0 2.4e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase PITH PF06201.13 EER22927.1 - 3.5e-39 134.5 0.1 5.8e-39 133.7 0.0 1.4 2 0 0 2 2 2 1 PITH domain Thioredoxin PF00085.20 EER22927.1 - 2.6e-25 88.4 0.1 5.9e-25 87.2 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.6 EER22927.1 - 5.9e-07 29.9 0.3 3.7e-06 27.3 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EER22927.1 - 9e-07 29.1 0.1 2.7e-06 27.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EER22927.1 - 2.4e-06 27.1 0.2 1.4e-05 24.6 0.1 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EER22927.1 - 0.00027 21.0 0.1 0.00059 20.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EER22927.1 - 0.0034 17.1 0.3 0.042 13.6 0.0 2.1 1 1 1 2 2 2 1 Redoxin HyaE PF07449.11 EER22927.1 - 0.006 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EER22927.1 - 0.023 14.6 0.3 0.11 12.4 0.2 1.9 1 1 0 1 1 1 0 AhpC/TSA family TRAM PF01938.20 EER22927.1 - 0.074 13.1 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 TRAM domain Thioredoxin_9 PF14595.6 EER22927.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin zf-C2H2 PF00096.26 EER22928.1 - 7.6e-11 41.8 16.4 3.1e-06 27.3 0.5 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER22928.1 - 3.2e-07 30.5 12.9 7.9e-07 29.2 4.8 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER22928.1 - 6.7e-07 29.6 15.1 0.0013 19.4 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER22928.1 - 1e-05 25.7 2.9 0.028 14.7 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER22928.1 - 5.3e-05 23.5 4.6 0.0067 16.8 0.4 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EER22928.1 - 0.0001 22.2 9.2 0.0057 16.6 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EER22928.1 - 0.017 14.7 10.7 0.083 12.5 0.2 3.6 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_UBZ PF18439.1 EER22928.1 - 0.25 10.9 1.7 2 8.1 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_2 PF12756.7 EER22928.1 - 0.48 10.8 3.6 16 5.9 0.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 EER22928.1 - 0.69 10.0 5.5 0.28 11.2 1.7 2.2 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 EER22928.1 - 0.87 9.4 8.2 3.1 7.6 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-LYAR PF08790.11 EER22928.1 - 0.98 9.4 6.3 3.1 7.8 0.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 EER22928.1 - 3.3 8.2 6.6 87 3.7 6.6 2.6 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 EER22928.1 - 9.2 7.0 6.3 40 4.9 0.4 3.0 2 1 0 3 3 2 0 Zinc finger C2H2-type, 3 repeats Diphthami_syn_2 PF01902.17 EER22929.1 - 1.1e-17 64.3 0.0 3e-05 23.6 0.0 4.3 4 0 0 4 4 4 4 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EER22929.1 - 2.1e-16 60.1 0.0 2.7e-09 37.1 0.0 3.6 3 0 0 3 3 3 2 Endoribonuclease L-PSP Adeno_E1B_55K_N PF04623.12 EER22929.1 - 0.076 13.7 2.1 0.22 12.3 2.1 1.7 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus DUF3543 PF12063.8 EER22931.1 - 4.6e-95 317.8 0.1 7.2e-95 317.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EER22931.1 - 4.5e-59 200.0 0.0 8.2e-59 199.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER22931.1 - 6.4e-41 140.3 0.0 1.2e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AA_permease_2 PF13520.6 EER22932.1 - 3e-80 270.1 42.3 1.1e-79 268.2 42.3 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER22932.1 - 1.1e-15 57.2 31.6 1.1e-15 57.2 31.6 2.0 2 1 0 2 2 2 1 Amino acid permease Pkinase PF00069.25 EER22933.1 - 4.1e-07 29.6 0.0 8.7e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain ERAP1_C PF11838.8 EER22934.1 - 6.9e-86 288.6 0.6 6.9e-86 288.6 0.6 2.2 2 1 1 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EER22934.1 - 1.8e-83 279.4 2.2 2.7e-83 278.8 2.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EER22934.1 - 6.3e-53 179.7 0.9 9.5e-53 179.2 0.9 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF4917 PF16263.5 EER22934.1 - 0.065 12.6 0.0 5.2 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4917) Pkinase PF00069.25 EER22935.1 - 1.3e-05 24.7 0.0 1.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain His_Phos_2 PF00328.22 EER22936.1 - 4.1e-69 233.8 0.0 4.8e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Peptidase_C10 PF01640.17 EER22936.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase C10 family Ribophorin_II PF05817.14 EER22938.1 - 1.5e-26 93.2 1.3 3.3e-26 92.0 1.3 1.5 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Piwi PF02171.17 EER22939.1 - 1.2e-74 251.3 0.0 1.6e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EER22939.1 - 2.6e-21 76.7 0.1 4.6e-21 75.9 0.1 1.4 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EER22939.1 - 3.7e-12 45.7 0.0 1.1e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 EER22939.1 - 4.5e-09 36.5 0.1 2.2e-08 34.3 0.1 2.1 2 0 0 2 2 2 1 Argonaute linker 2 domain PAZ PF02170.22 EER22939.1 - 5.9e-08 32.6 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 PAZ domain adh_short_C2 PF13561.6 EER22940.1 - 6.9e-57 192.7 0.3 8e-57 192.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER22940.1 - 3.5e-49 166.9 0.5 4.3e-49 166.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER22940.1 - 3.1e-16 59.8 0.2 4.2e-16 59.4 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EER22940.1 - 0.00055 19.5 0.1 0.00077 19.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EER22940.1 - 0.076 12.4 0.1 0.13 11.6 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PLA2_B PF01735.18 EER22941.1 - 1.9e-188 626.9 0.0 2.1e-188 626.7 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SWIRM-assoc_2 PF16496.5 EER22942.1 - 0.023 13.6 0.0 0.023 13.6 0.0 2.8 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal PTCB-BRCT PF12738.7 EER22942.1 - 0.055 13.4 0.3 1.6 8.7 0.2 2.4 2 0 0 2 2 2 0 twin BRCT domain DAHP_synth_2 PF01474.16 EER22943.1 - 1.7e-206 685.9 0.0 2e-206 685.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family CdiI_3 PF18616.1 EER22944.1 - 0.03 14.2 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 CDI immunity proteins MFS_1 PF07690.16 EER22945.1 - 2.9e-22 79.1 20.8 2.9e-22 79.1 20.8 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER22945.1 - 5.9e-05 22.1 1.7 9.1e-05 21.5 1.7 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Aldose_epim PF01263.20 EER22946.1 - 1.5e-45 155.8 0.0 1.8e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.8 EER22947.1 - 3.7e-129 431.0 0.0 5.7e-129 430.4 0.0 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.9 EER22948.1 - 3.2e-104 349.5 0.1 3.6e-104 349.4 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Polysacc_synt_4 PF04669.13 EER22949.1 - 2e-21 76.5 0.6 6.2e-20 71.6 0.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis UCMA PF17085.5 EER22949.1 - 0.0017 18.4 0.1 0.0026 17.8 0.1 1.3 1 0 0 1 1 1 1 Unique cartilage matrix associated protein BBP1_C PF15272.6 EER22949.1 - 0.051 13.4 0.1 0.057 13.2 0.1 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Sugar_tr PF00083.24 EER22950.1 - 4.7e-139 464.1 20.8 5.5e-139 463.9 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER22950.1 - 5.5e-28 97.9 43.1 7.5e-23 81.0 18.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EER22950.1 - 1.8e-08 33.4 11.8 3.3e-05 22.6 3.8 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EER22950.1 - 0.028 13.3 12.5 0.051 12.4 0.6 2.5 1 1 0 2 2 2 0 MFS_1 like family Mannitol_dh_C PF08125.13 EER22951.1 - 4.9e-40 137.6 0.0 8.3e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EER22951.1 - 2.8e-18 66.5 0.2 8.7e-18 64.9 0.0 1.9 2 1 1 3 3 3 1 Mannitol dehydrogenase Rossmann domain Myb_DNA-binding PF00249.31 EER22953.1 - 2.9e-10 40.2 0.0 9.2e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EER22953.1 - 1.1e-09 38.0 8.5 1.9e-09 37.1 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EER22953.1 - 1.2e-09 38.3 0.2 4.4e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain PG_binding_1 PF01471.18 EER22953.1 - 0.035 14.3 0.0 0.091 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Abhydrolase_1 PF00561.20 EER22953.1 - 0.041 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HAMP_N3 PF18575.1 EER22953.1 - 0.09 12.4 0.5 0.66 9.6 0.0 2.3 2 0 0 2 2 2 0 HAMP N-terminal domain 3 DUF3232 PF11554.8 EER22953.1 - 0.1 13.0 0.9 0.21 12.0 0.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3232) Pkinase PF00069.25 EER22954.1 - 5.4e-70 235.8 0.0 7e-70 235.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER22954.1 - 5.7e-33 114.3 0.0 7.9e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EER22954.1 - 2.5e-10 40.9 0.2 7.3e-10 39.4 0.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EER22954.1 - 1.9e-06 27.1 0.1 2.8e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EER22954.1 - 0.0063 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2 PF00168.30 EER22954.1 - 0.041 14.2 0.0 0.096 13.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain Coatomer_WDAD PF04053.14 EER22955.1 - 1.4e-167 558.2 0.0 2.9e-167 557.3 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EER22955.1 - 1.8e-39 133.0 5.5 1.9e-06 28.5 0.0 8.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER22955.1 - 1.4e-06 28.5 0.1 4.5 7.6 0.0 5.6 4 2 2 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER22955.1 - 6.1e-05 21.9 3.5 0.19 10.4 0.1 4.7 2 1 3 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EER22955.1 - 0.068 13.2 0.0 14 5.8 0.0 3.7 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.14 EER22956.1 - 9.8e-28 95.8 5.3 2e-26 91.6 0.1 2.8 2 1 0 2 2 2 2 ETC complex I subunit conserved region Thioredoxin PF00085.20 EER22957.1 - 2.8e-44 149.3 0.1 1.5e-23 82.8 0.0 4.2 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EER22957.1 - 4.9e-11 42.9 0.0 0.00015 21.8 0.0 4.2 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EER22957.1 - 4.9e-05 23.7 2.1 0.079 13.4 0.1 3.7 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EER22957.1 - 0.0001 22.5 0.4 0.36 11.2 0.0 3.9 3 1 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 EER22957.1 - 0.0033 17.4 0.0 4.4 7.3 0.0 2.9 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE DUF3557 PF12078.8 EER22957.1 - 0.052 13.5 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3557) OST3_OST6 PF04756.13 EER22957.1 - 0.6 9.4 3.5 6.6 6.0 0.1 2.6 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EER22957.1 - 1.2 9.4 4.4 0.66 10.2 0.1 2.7 4 0 0 4 4 4 0 Thioredoxin-like Fungal_trans_2 PF11951.8 EER22958.1 - 1.5e-110 369.7 0.5 2.7e-110 368.8 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER22958.1 - 1.9e-06 27.9 11.3 2.8e-06 27.4 10.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4250 PF14056.6 EER22958.1 - 0.2 11.7 0.1 0.57 10.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) SAM_2 PF07647.17 EER22959.1 - 8.7e-10 38.6 0.1 1.6e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EER22959.1 - 7e-08 32.8 0.1 1.6e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 EER22959.1 - 6.7e-07 29.8 0.1 2.3e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 PH domain SAM_3 PF18016.1 EER22959.1 - 0.01 15.6 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PH_9 PF15410.6 EER22959.1 - 0.013 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain SAM_Ste50p PF09235.10 EER22959.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif SAM_PNT PF02198.16 EER22959.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain WD40 PF00400.32 EER22960.1 - 7.4e-19 67.7 25.2 2.4e-06 28.1 0.2 7.0 6 2 1 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER22960.1 - 1e-12 48.2 0.1 0.013 15.8 0.0 5.3 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER22960.1 - 0.22 11.4 0.0 1.8 8.4 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A HNH_2 PF13391.6 EER22961.1 - 4.3e-15 55.6 0.0 9.5e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Gp23 PF07068.11 EER22961.1 - 0.25 10.1 0.0 0.32 9.7 0.0 1.1 1 0 0 1 1 1 0 Major capsid protein Gp23 UAF_Rrn10 PF05234.11 EER22962.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 UAF complex subunit Rrn10 Mnd1 PF03962.15 EER22963.1 - 7.1e-25 87.1 0.3 1.6e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 Mnd1 HTH domain Tektin PF03148.14 EER22963.1 - 0.0053 15.6 1.2 0.0087 14.9 0.3 1.8 1 1 1 2 2 2 1 Tektin family LPP PF04728.13 EER22963.1 - 0.01 16.2 1.1 3.3 8.2 0.2 2.5 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Seryl_tRNA_N PF02403.22 EER22963.1 - 0.01 16.0 5.1 0.02 15.1 5.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain LZ3wCH PF18517.1 EER22963.1 - 0.022 14.8 0.1 0.022 14.8 0.1 2.7 4 0 0 4 4 4 0 Leucine zipper with capping helix domain FapA PF03961.13 EER22963.1 - 0.024 13.3 0.6 0.028 13.0 0.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RNA_pol_Rpc34 PF05158.12 EER22963.1 - 0.025 13.9 0.1 0.041 13.3 0.0 1.3 1 1 0 1 1 1 0 RNA polymerase Rpc34 subunit IL11 PF07400.11 EER22963.1 - 0.12 12.0 0.2 0.33 10.6 0.2 1.7 1 1 0 1 1 1 0 Interleukin 11 AAA_13 PF13166.6 EER22963.1 - 0.14 10.8 1.5 0.16 10.5 1.5 1.2 1 0 0 1 1 1 0 AAA domain DUF3496 PF12001.8 EER22963.1 - 0.36 11.2 2.6 3.7 8.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) LacAB_rpiB PF02502.18 EER22964.1 - 2.7e-44 150.5 0.3 3.1e-44 150.3 0.3 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase TIM PF00121.18 EER22965.1 - 3.9e-43 147.6 0.0 6.5e-43 146.8 0.0 1.4 1 1 0 1 1 1 1 Triosephosphate isomerase U-box PF04564.15 EER22966.1 - 8.8e-24 83.5 0.0 1.9e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_16 PF13432.6 EER22966.1 - 1.3e-07 32.2 1.2 0.0056 17.3 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EER22966.1 - 6.5e-06 25.9 8.5 0.0038 17.2 1.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EER22966.1 - 5.7e-05 22.7 0.8 5.7e-05 22.7 0.8 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 EER22966.1 - 9e-05 22.1 4.9 0.0011 18.7 1.7 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EER22966.1 - 0.00013 22.4 7.0 0.012 16.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 EER22966.1 - 0.0012 19.5 3.6 0.0021 18.8 3.6 1.4 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_14 PF13428.6 EER22966.1 - 0.0015 19.2 2.1 3.5 8.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EER22966.1 - 0.006 16.8 0.3 0.61 10.3 0.0 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-Nse PF11789.8 EER22966.1 - 0.0092 15.8 0.0 0.025 14.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 EER22966.1 - 0.016 15.3 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_4 PF07721.14 EER22966.1 - 0.023 15.3 0.4 0.18 12.5 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER22966.1 - 0.029 14.7 8.3 0.13 12.6 0.1 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EER22966.1 - 0.061 13.2 0.4 12 5.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat C4bp_oligo PF18453.1 EER22966.1 - 0.07 13.3 0.9 3.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Oligomerization domain of C4b-binding protein alpha zf-RING_UBOX PF13445.6 EER22966.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger CSS-motif PF12792.7 EER22966.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 CSS motif domain associated with EAL TPR_7 PF13176.6 EER22966.1 - 0.4 10.8 1.8 4.4 7.6 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EER22966.1 - 1.3 9.4 6.3 7.7 7.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EER22966.1 - 1.7 9.4 8.5 26 5.7 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ACBP PF00887.19 EER22967.1 - 2.9e-20 72.3 0.1 3.5e-20 72.0 0.1 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.12 EER22968.1 - 1.4e-163 544.7 0.0 1.7e-163 544.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EER22968.1 - 0.011 15.6 0.1 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain DNA_gyraseB PF00204.25 EER22968.1 - 0.17 11.4 0.0 0.4 10.1 0.0 1.6 1 0 0 1 1 1 0 DNA gyrase B AA_permease_2 PF13520.6 EER22969.1 - 7.3e-70 235.9 44.3 8.7e-70 235.7 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER22969.1 - 3.7e-17 62.1 35.2 4.9e-17 61.7 35.2 1.2 1 0 0 1 1 1 1 Amino acid permease Caps_synth PF05704.12 EER22970.1 - 1.1e-09 38.1 0.0 2.5e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 EER22970.1 - 0.0012 19.4 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Arrestin_N PF00339.29 EER22971.1 - 5.6e-14 52.4 0.0 4e-13 49.6 0.0 2.3 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EER22971.1 - 5.1e-06 27.0 0.4 0.00014 22.3 0.0 3.1 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain DHO_dh PF01180.21 EER22972.1 - 2.7e-59 200.8 0.1 5.5e-51 173.5 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase SelP_N PF04592.14 EER22973.1 - 1.3 8.4 10.0 1.7 8.0 10.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-H2C2_2 PF13465.6 EER22974.1 - 3.3e-06 27.3 12.2 1.3e-05 25.4 1.4 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER22974.1 - 0.0001 22.8 15.0 0.014 16.2 5.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 EER22974.1 - 0.00014 22.1 4.9 0.00027 21.2 4.9 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EER22974.1 - 0.00086 19.5 4.8 0.064 13.6 1.2 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EER22974.1 - 0.017 15.5 14.5 0.093 13.2 7.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type APG5 PF04106.12 EER22975.1 - 2.6e-66 223.5 0.0 3.5e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 GMC_oxred_N PF00732.19 EER22976.1 - 2.6e-54 184.6 0.0 3.3e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EER22976.1 - 1e-32 113.6 0.0 1.8e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EER22976.1 - 0.0016 18.6 0.2 0.0048 17.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EER22976.1 - 0.0031 16.6 0.1 0.0046 16.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EER22976.1 - 0.015 14.9 0.3 0.033 13.8 0.3 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EER22976.1 - 0.072 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EER22976.1 - 0.082 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.13 EER22977.1 - 4.8e-29 101.6 0.0 8.8e-29 100.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EER22977.1 - 3.2e-08 33.7 0.0 4.6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EER22977.1 - 0.00084 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EER22977.1 - 0.04 14.2 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_23 PF13489.6 EER22978.1 - 1.3e-22 80.4 0.0 2.1e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER22978.1 - 2e-10 41.2 0.0 5.2e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER22978.1 - 9.6e-08 32.0 0.0 1.2e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER22978.1 - 6.3e-07 30.1 0.0 1.7e-06 28.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER22978.1 - 1.9e-06 28.4 0.0 4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EER22978.1 - 0.032 13.6 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EER22978.1 - 0.076 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 EER22978.1 - 0.079 13.1 0.0 0.16 12.0 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EER22978.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase SHR3_chaperone PF08229.11 EER22979.1 - 7.8e-83 276.1 0.0 9.3e-83 275.8 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5453 PF17534.2 EER22979.1 - 0.036 14.0 0.4 0.077 13.0 0.1 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5453) Herpes_DNAp_acc PF04929.12 EER22982.1 - 1.1 8.2 10.6 0.78 8.6 8.9 1.4 1 1 0 1 1 1 0 Herpes DNA replication accessory factor DUF3446 PF11928.8 EER22982.1 - 4.6 7.6 21.7 0.21 11.9 10.1 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain ABC_membrane PF00664.23 EER22983.1 - 4e-56 190.7 38.3 4.5e-36 124.9 17.1 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EER22983.1 - 4.7e-47 159.9 1.1 7.6e-28 97.7 0.0 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EER22983.1 - 9.3e-06 25.2 4.6 0.026 14.0 1.2 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EER22983.1 - 2.4e-05 24.4 0.7 0.019 15.1 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EER22983.1 - 9e-05 22.4 4.1 0.57 9.9 0.2 4.6 4 1 1 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EER22983.1 - 0.00012 22.5 0.0 0.45 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EER22983.1 - 0.00058 19.5 1.7 0.39 10.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EER22983.1 - 0.0012 19.4 9.1 0.42 11.1 0.1 3.6 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EER22983.1 - 0.0012 18.8 1.6 0.94 9.4 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EER22983.1 - 0.002 17.5 0.0 0.47 9.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EER22983.1 - 0.0043 16.8 2.7 1.1 9.0 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EER22983.1 - 0.011 16.0 2.0 3.6 7.9 0.1 3.2 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EER22983.1 - 0.012 14.6 2.5 2 7.3 0.2 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 EER22983.1 - 0.015 15.0 0.0 6 6.5 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 EER22983.1 - 0.022 15.0 0.1 9 6.5 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EER22983.1 - 0.029 14.4 6.5 0.72 9.9 0.1 3.5 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 EER22983.1 - 0.12 12.1 1.7 9.1 6.0 0.3 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EER22983.1 - 0.13 12.5 2.7 1 9.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EER22983.1 - 0.19 12.3 2.7 19 5.8 0.1 3.3 3 0 0 3 3 3 0 AAA domain CDC45 PF02724.14 EER22983.1 - 0.26 9.6 2.2 0.5 8.6 2.2 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF87 PF01935.17 EER22983.1 - 8.9 6.3 11.0 0.3 11.1 0.4 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain Aminotran_3 PF00202.21 EER22984.1 - 2.1e-118 395.6 0.0 2.3e-118 395.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EER22984.1 - 0.0058 15.9 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.17 EER22985.1 - 6.9e-80 269.3 15.3 8.5e-80 269.0 15.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ArfGap PF01412.18 EER22986.1 - 2.3e-39 134.1 0.1 4.5e-39 133.2 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf FtsJ PF01728.19 EER22987.1 - 8.4e-13 48.8 0.0 1.2e-12 48.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF1726 PF08351.11 EER22987.1 - 0.031 14.2 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) SET PF00856.28 EER22988.1 - 4.5e-06 27.2 2.2 2.6e-05 24.7 0.1 2.8 2 1 0 2 2 2 1 SET domain PHD PF00628.29 EER22988.1 - 0.00019 21.3 9.9 0.00039 20.3 9.9 1.6 1 0 0 1 1 1 1 PHD-finger CDC73_C PF05179.14 EER22989.1 - 7.9e-58 194.6 0.0 1.7e-57 193.5 0.0 1.6 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal DUF5086 PF16985.5 EER22989.1 - 0.12 12.3 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5086) RGS PF00615.19 EER22990.1 - 5.8e-31 107.2 0.0 1.2e-30 106.2 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 EER22990.1 - 2.4e-23 82.0 0.0 4.1e-17 62.0 0.0 3.3 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ORC4_C PF14629.6 EER22991.1 - 1.3e-48 165.3 0.0 1.8e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EER22991.1 - 3.7e-13 50.2 0.1 1e-12 48.8 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EER22991.1 - 9.6e-07 29.3 0.0 2.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EER22991.1 - 8.6e-06 26.1 0.1 2.3e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EER22991.1 - 7.2e-05 23.1 0.0 0.00019 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EER22991.1 - 0.0082 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EER22991.1 - 0.011 15.6 0.0 0.029 14.3 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EER22991.1 - 0.014 15.4 0.1 0.066 13.3 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 EER22991.1 - 0.014 15.1 0.0 0.061 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EER22991.1 - 0.039 13.3 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EER22991.1 - 0.042 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EER22991.1 - 0.088 12.7 2.1 0.27 11.1 0.5 2.4 2 1 0 2 2 2 0 NACHT domain AAA_5 PF07728.14 EER22991.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) 4HBT PF03061.22 EER22992.1 - 2.2e-12 47.2 0.0 3.3e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EER22992.1 - 0.0014 18.9 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily NOT2_3_5 PF04153.18 EER22993.1 - 1.3e-26 93.3 0.0 1.3e-26 93.3 0.0 2.0 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.13 EER22994.1 - 3.1e-20 72.1 0.0 4.5e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.18 EER22995.1 - 3.8e-190 632.0 0.0 4.9e-190 631.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EER22995.1 - 0.032 14.5 0.0 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SMC_N PF02463.19 EER22996.1 - 2.7e-69 233.0 6.4 2.5e-68 229.8 6.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EER22996.1 - 9e-22 77.6 1.0 5.2e-21 75.1 0.3 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EER22996.1 - 1.2e-14 55.3 4.0 1.2e-14 55.3 4.0 6.6 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 EER22996.1 - 4.5e-11 43.1 7.7 0.00019 21.3 0.1 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EER22996.1 - 3.3e-05 23.8 15.6 3.3e-05 23.8 15.6 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EER22996.1 - 0.00013 21.6 0.1 0.00032 20.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HIP1_clath_bdg PF16515.5 EER22996.1 - 0.0024 18.4 9.9 0.0024 18.4 9.9 9.1 3 2 7 10 10 10 1 Clathrin-binding domain of Huntingtin-interacting protein 1 HSBP1 PF06825.12 EER22996.1 - 0.0028 17.5 17.6 0.032 14.1 0.9 5.2 6 0 0 6 6 6 2 Heat shock factor binding protein 1 ABC_tran PF00005.27 EER22996.1 - 0.071 13.6 0.0 0.071 13.6 0.0 5.5 4 2 0 4 4 4 0 ABC transporter DUF1359 PF07097.11 EER22996.1 - 0.81 10.0 16.1 0.24 11.6 0.5 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1359) CUE PF02845.16 EER22997.1 - 2.4e-10 39.9 0.0 4.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 EER22997.1 - 0.013 15.1 11.2 0.023 14.4 11.2 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) HTH_32 PF13565.6 EER22997.1 - 0.022 15.4 0.9 0.072 13.7 0.0 2.1 2 1 0 2 2 2 0 Homeodomain-like domain Sld5 PF05916.11 EER22998.1 - 1.5e-36 125.1 0.0 4e-36 123.8 0.0 1.7 1 1 0 1 1 1 1 GINS complex protein SQS_PSY PF00494.19 EER22998.1 - 0.089 12.3 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Squalene/phytoene synthase TPR_9 PF13371.6 EER22999.1 - 2e-08 34.3 1.8 1.5e-06 28.2 0.3 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER22999.1 - 4.2e-06 26.3 0.1 0.5 10.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EER22999.1 - 2.6e-05 24.7 8.0 0.0019 18.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EER22999.1 - 4.4e-05 23.3 2.6 0.29 11.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EER22999.1 - 0.00022 21.2 0.0 0.11 12.8 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER22999.1 - 0.0072 16.0 0.0 0.036 13.8 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 EER22999.1 - 0.0074 16.6 0.0 0.12 12.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EER22999.1 - 0.0088 16.0 0.1 3.9 7.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EER22999.1 - 0.019 15.5 4.3 3.4 8.2 0.2 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat NARP1 PF12569.8 EER22999.1 - 0.033 13.1 0.0 0.05 12.5 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 EER22999.1 - 0.042 14.7 7.5 1.7 9.7 0.1 3.9 2 1 2 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER22999.1 - 0.16 12.3 2.6 15 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EER22999.1 - 0.29 11.1 4.7 1.3 9.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DIE2_ALG10 PF04922.12 EER23000.1 - 4.6e-130 434.4 9.4 6.6e-130 433.9 9.4 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family UPF0139 PF03669.13 EER23000.1 - 0.071 13.0 0.1 0.31 10.9 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Polyketide_cyc PF03364.20 EER23001.1 - 3.1e-18 66.2 0.0 4.6e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sod_Fe_C PF02777.18 EER23002.1 - 2.6e-16 59.6 0.0 7.2e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain PIG-S PF10510.9 EER23004.1 - 9.9e-184 611.9 3.0 1.2e-183 611.7 3.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein FmiP_Thoc5 PF09766.9 EER23005.1 - 5e-31 108.3 9.0 7.1e-31 107.8 9.0 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 EER23005.1 - 0.011 15.9 3.2 0.011 15.9 3.2 1.9 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus Casc1_N PF15927.5 EER23005.1 - 0.23 11.1 12.6 0.036 13.7 8.1 1.8 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DDE_Tnp_ISL3 PF01610.17 EER23005.1 - 0.91 9.2 5.6 0.24 11.1 2.4 1.6 2 0 0 2 2 2 0 Transposase DUF349 PF03993.12 EER23005.1 - 1.1 9.5 10.0 0.21 11.9 5.5 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) YabA PF06156.13 EER23005.1 - 1.3 9.7 5.7 9.5 6.9 1.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA HlyIII PF03006.20 EER23006.1 - 6.6e-61 205.9 20.4 8.8e-61 205.5 20.4 1.2 1 0 0 1 1 1 1 Haemolysin-III related Asr PF06392.11 EER23006.1 - 0.027 14.8 0.5 0.058 13.8 0.5 1.4 1 0 0 1 1 1 0 Acid shock protein repeat SPC12 PF06645.13 EER23006.1 - 0.027 14.5 0.6 0.027 14.5 0.6 2.4 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) SMBP PF16785.5 EER23006.1 - 0.088 13.0 4.3 7.1 6.9 1.5 2.4 1 1 1 2 2 2 0 Small metal-binding protein GlnD_UR_UTase PF08335.11 EER23006.1 - 0.54 10.4 3.1 8.4 6.5 0.3 2.4 1 1 1 2 2 2 0 GlnD PII-uridylyltransferase Methyltransf_12 PF08242.12 EER23007.1 - 2.5e-17 63.4 0.0 7.2e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23007.1 - 6.9e-16 58.7 0.0 1.3e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER23007.1 - 7.1e-14 52.2 0.0 1.5e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER23007.1 - 3.8e-12 46.3 0.1 8.5e-12 45.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER23007.1 - 1.5e-07 31.4 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER23007.1 - 1.8e-07 30.8 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EER23007.1 - 0.00066 20.7 0.0 0.002 19.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 EER23007.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 EER23007.1 - 0.0014 17.8 0.0 0.1 11.8 0.0 2.2 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 EER23007.1 - 0.0024 17.8 0.0 0.033 14.0 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase DUF3419 PF11899.8 EER23007.1 - 0.0042 16.3 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) CMAS PF02353.20 EER23007.1 - 0.0069 15.7 0.0 0.015 14.6 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 EER23007.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 EER23007.1 - 0.055 13.5 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Diphthamide_syn PF01866.17 EER23009.1 - 4.7e-83 279.1 0.0 9.9e-82 274.8 0.0 1.9 2 0 0 2 2 2 2 Putative diphthamide synthesis protein Fe-ADH PF00465.19 EER23010.1 - 4.8e-77 259.2 0.1 5.6e-77 259.0 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EER23010.1 - 4.5e-13 49.5 0.0 6.1e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase IMS_C PF11799.8 EER23010.1 - 0.0054 17.4 0.0 0.026 15.2 0.0 2.1 1 1 0 1 1 1 1 impB/mucB/samB family C-terminal domain ANAPC4_WD40 PF12894.7 EER23011.1 - 0.00028 21.1 0.0 1.4 9.2 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EER23011.1 - 0.023 14.3 5.8 1.2 8.7 5.7 2.4 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.6 EER23011.1 - 0.21 12.1 3.1 24 5.6 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain RAB3GAP2_N PF14655.6 EER23011.1 - 0.22 10.8 0.0 5.7 6.1 0.0 2.6 2 1 1 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nop14 PF04147.12 EER23011.1 - 2.9 6.0 5.7 3.7 5.6 5.7 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3638 PF12340.8 EER23013.1 - 3.1e-67 226.2 0.2 1.4e-57 194.6 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.8 EER23013.1 - 2.3e-15 55.7 0.0 5.4e-15 54.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) JmjC PF02373.22 EER23014.1 - 2e-06 28.2 0.0 5.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EER23014.1 - 1.8e-05 24.9 11.6 1.8e-05 24.9 11.6 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 ZZ PF00569.17 EER23014.1 - 9.7e-05 22.1 8.3 9.7e-05 22.1 8.3 2.4 2 0 0 2 2 2 1 Zinc finger, ZZ type Cupin_2 PF07883.11 EER23014.1 - 0.0092 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain 2OG-FeII_Oxy_5 PF13759.6 EER23014.1 - 0.14 12.6 0.0 0.59 10.6 0.0 2.1 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Cu-oxidase_3 PF07732.15 EER23015.1 - 2.4e-41 140.5 0.7 2.3e-40 137.3 0.2 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EER23015.1 - 1.1e-35 122.3 0.8 1.5e-31 108.9 0.1 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EER23015.1 - 5.8e-26 91.5 0.0 1.4e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Sulfatase PF00884.23 EER23016.1 - 2e-19 70.2 0.2 4.4e-19 69.0 0.1 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 EER23016.1 - 7.9e-06 25.7 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EER23016.1 - 0.028 13.1 0.1 0.044 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) MAPEG PF01124.18 EER23016.1 - 0.13 12.2 4.7 0.081 12.8 1.6 2.2 2 0 0 2 2 2 0 MAPEG family AMP-binding PF00501.28 EER23017.1 - 9.5e-66 222.1 0.0 1.3e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER23017.1 - 5.7e-08 33.6 0.0 1.1e-07 32.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BiPBP_C PF06832.12 EER23017.1 - 0.19 11.8 0.9 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Penicillin-Binding Protein C-terminus Family Aminotran_1_2 PF00155.21 EER23018.1 - 5.7e-44 150.8 0.0 7.3e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EER23018.1 - 4.1e-09 35.4 0.0 6.3e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EER23018.1 - 3.3e-08 32.9 0.0 4.9e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EER23018.1 - 3.5e-08 33.1 0.0 6.3e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EER23018.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family ABC2_membrane PF01061.24 EER23019.1 - 1.2e-39 135.9 19.0 1.1e-38 132.8 19.7 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EER23019.1 - 3.8e-25 89.0 0.0 8.1e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EER23019.1 - 2.8e-06 27.4 0.0 0.055 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EER23019.1 - 0.00063 19.0 28.7 0.0022 17.2 27.5 2.4 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 EER23019.1 - 0.0073 16.0 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EER23019.1 - 0.025 14.5 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 EER23019.1 - 0.028 14.0 0.0 0.088 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EER23019.1 - 0.041 14.2 0.2 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EER23019.1 - 0.051 13.0 0.0 0.58 9.6 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EER23019.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 EER23019.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EER23019.1 - 0.13 12.6 0.7 0.22 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EER23019.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EER23019.1 - 0.18 12.3 0.1 0.18 12.3 0.1 1.7 2 0 0 2 2 1 0 AAA domain Retinal PF15449.6 EER23019.1 - 0.22 9.2 9.9 0.3 8.8 9.9 1.0 1 0 0 1 1 1 0 Retinal protein EGF_2 PF07974.13 EER23019.1 - 3.7 8.0 32.6 0.5 10.8 12.6 3.5 3 0 0 3 3 3 0 EGF-like domain MFS_1 PF07690.16 EER23020.1 - 5.5e-19 68.3 37.5 1.8e-15 56.8 23.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cornichon PF03311.14 EER23021.1 - 2.6e-49 166.6 14.1 2.9e-49 166.4 14.1 1.0 1 0 0 1 1 1 1 Cornichon protein HeLo PF14479.6 EER23022.1 - 0.00025 20.9 1.8 0.00074 19.4 1.8 1.8 1 1 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 EER23022.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23022.1 - 0.092 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 EER23023.1 - 2.1e-28 98.7 0.0 7.7e-08 32.8 0.1 6.0 5 1 1 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER23023.1 - 5.4e-26 90.6 0.0 5.3e-06 26.9 0.0 6.4 5 1 0 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER23023.1 - 3.6e-19 66.8 0.3 0.026 15.1 0.0 9.2 9 0 0 9 9 9 3 Ankyrin repeat Pkinase PF00069.25 EER23023.1 - 5.5e-18 65.3 0.0 9.7e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank PF00023.30 EER23023.1 - 6e-18 64.4 0.4 0.11 13.0 0.0 8.7 8 1 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 EER23023.1 - 2.6e-15 56.3 1.1 0.00045 20.5 0.0 7.2 7 2 1 8 8 8 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 EER23023.1 - 6.3e-09 35.5 0.0 1.7e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EER23023.1 - 0.035 13.1 0.1 0.055 12.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EER23023.1 - 0.04 12.7 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EER23023.1 - 0.092 12.0 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Kinase-like DUF5565 PF17720.1 EER23025.1 - 0.027 13.3 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5565) WD40 PF00400.32 EER23027.1 - 8.4e-31 105.6 13.1 9.9e-08 32.5 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23027.1 - 2.6e-13 50.1 0.1 0.00037 20.7 0.1 4.8 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EER23027.1 - 0.065 12.2 1.6 5.8 5.8 0.0 3.6 2 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Oxidored_molyb PF00174.19 EER23028.1 - 6.9e-55 185.3 0.0 1.2e-54 184.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EER23028.1 - 1.4e-39 135.3 0.5 3.2e-39 134.1 0.5 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 EER23028.1 - 1.4e-23 83.1 0.0 2.9e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EER23028.1 - 3.4e-23 82.4 0.3 3.9e-22 79.0 0.0 2.9 3 1 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EER23028.1 - 6.6e-17 61.4 0.0 1.5e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EER23028.1 - 0.00099 19.3 0.9 0.003 17.7 0.0 2.3 3 0 0 3 3 3 1 Ferric reductase NAD binding domain EF-hand_1 PF00036.32 EER23029.1 - 1.5e-10 39.9 10.2 7.3e-05 22.0 0.3 4.0 4 0 0 4 4 4 2 EF hand ZZ PF00569.17 EER23029.1 - 2.7e-10 39.9 4.7 4.9e-10 39.0 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 EER23029.1 - 1.3e-09 37.2 5.6 0.00028 20.6 0.2 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EER23029.1 - 2.4e-08 34.3 2.7 0.0002 21.8 0.2 3.4 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EER23029.1 - 0.00048 19.9 5.1 0.12 12.2 0.2 3.5 4 0 0 4 4 4 2 EF-hand domain pair C1_2 PF03107.16 EER23029.1 - 0.01 16.2 3.7 0.02 15.2 3.7 1.5 1 0 0 1 1 1 0 C1 domain EF-hand_5 PF13202.6 EER23029.1 - 0.027 14.0 10.3 0.13 11.8 0.2 3.3 4 0 0 4 4 4 0 EF hand MFS_1 PF07690.16 EER23030.1 - 1.5e-48 165.5 49.7 1.5e-48 165.5 49.7 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER23030.1 - 1.5e-12 47.1 7.5 1.5e-12 47.1 7.5 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter Peptidase_M24 PF00557.24 EER23031.1 - 5.6e-47 160.1 0.0 6.3e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 FAD_binding_3 PF01494.19 EER23032.1 - 5.9e-15 55.4 0.0 1.8e-13 50.5 0.0 2.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EER23032.1 - 2.9e-05 23.6 2.3 0.032 13.6 0.4 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER23032.1 - 0.00033 20.0 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EER23032.1 - 0.00069 18.8 0.0 0.0019 17.3 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 EER23032.1 - 0.00094 18.9 0.1 0.0039 16.8 0.1 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EER23032.1 - 0.0041 15.9 0.1 0.0069 15.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EER23032.1 - 0.0052 15.9 0.1 0.0089 15.1 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EER23032.1 - 0.0092 16.5 0.0 0.057 14.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER23032.1 - 0.0093 16.2 0.5 0.031 14.5 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EER23032.1 - 0.016 14.5 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2235 PF09994.9 EER23032.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ribosomal_S8 PF00410.19 EER23034.1 - 4.5e-15 55.7 0.0 3e-14 53.1 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 Med12 PF09497.10 EER23034.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.5 1 1 0 1 1 1 0 Transcription mediator complex subunit Med12 Iso_dh PF00180.20 EER23037.1 - 2.7e-98 329.3 0.0 4.1e-98 328.7 0.0 1.2 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.14 EER23037.1 - 0.2 12.1 0.0 0.35 11.3 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1769 PF08588.10 EER23038.1 - 2.1e-26 91.9 0.1 4.5e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) APH PF01636.23 EER23039.1 - 3.1e-06 27.3 0.2 0.00028 20.9 0.2 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family NAD_binding_8 PF13450.6 EER23040.1 - 2e-09 37.5 0.0 4.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EER23040.1 - 3.8e-09 36.4 0.0 9.1e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EER23040.1 - 1.2e-07 31.4 0.1 2.6e-06 27.0 0.1 2.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EER23040.1 - 1.1e-06 28.1 0.2 1.4e-06 27.6 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EER23040.1 - 1.6e-06 27.1 0.1 3.3e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EER23040.1 - 3.4e-06 26.5 0.0 0.00031 20.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EER23040.1 - 4.3e-06 26.5 0.3 0.00013 21.7 0.6 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EER23040.1 - 6.4e-05 22.3 0.1 0.00032 20.1 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EER23040.1 - 0.00014 21.2 0.0 0.00082 18.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER23040.1 - 0.00091 19.7 0.4 0.013 16.1 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER23040.1 - 0.0022 17.3 0.1 0.0043 16.3 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EER23040.1 - 0.015 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 EER23040.1 - 0.019 15.2 0.2 0.033 14.4 0.2 1.4 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.12 EER23040.1 - 0.051 13.1 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EER23040.1 - 0.07 12.8 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EER23040.1 - 0.079 12.9 0.1 1.5 8.8 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EER23040.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Arm_3 PF16186.5 EER23040.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.7 1 0 0 1 1 1 0 Atypical Arm repeat NAD_Gly3P_dh_N PF01210.23 EER23040.1 - 0.16 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 EER23040.1 - 0.17 12.4 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TolA_bind_tri PF16331.5 EER23041.1 - 0.0082 16.2 4.4 0.0082 16.2 4.4 6.4 5 1 2 7 7 7 1 TolA binding protein trimerisation DASH_Hsk3 PF08227.11 EER23041.1 - 0.009 16.4 7.6 0.048 14.0 0.5 3.9 2 1 1 3 3 3 1 DASH complex subunit Hsk3 like KxDL PF10241.9 EER23041.1 - 0.014 15.6 3.7 0.014 15.6 3.7 5.0 3 1 2 5 5 5 0 Uncharacterized conserved protein ADIP PF11559.8 EER23041.1 - 0.39 10.8 50.1 0.59 10.2 0.1 6.4 2 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding Vac_Fusion PF02346.16 EER23041.1 - 0.62 9.7 4.4 24 4.6 0.2 3.7 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 MAD PF05557.13 EER23041.1 - 0.68 8.2 46.5 0.098 11.0 14.8 3.4 2 1 1 3 3 3 0 Mitotic checkpoint protein FH2 PF02181.23 EER23041.1 - 0.72 8.9 25.7 0.17 11.0 10.8 3.4 1 1 2 3 3 3 0 Formin Homology 2 Domain Filament PF00038.21 EER23041.1 - 1.5 8.3 48.5 8.5 5.9 6.0 5.1 3 1 1 4 4 4 0 Intermediate filament protein TMF_TATA_bd PF12325.8 EER23041.1 - 2.4 8.4 52.0 0.024 14.9 6.4 6.6 3 2 4 7 7 7 0 TATA element modulatory factor 1 TATA binding DUF16 PF01519.16 EER23041.1 - 3.1 8.3 20.1 1 9.9 0.2 4.2 1 1 3 4 4 4 0 Protein of unknown function DUF16 MscS_porin PF12795.7 EER23041.1 - 3.6 7.0 52.2 0.097 12.2 27.9 3.9 3 1 1 4 4 4 0 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 EER23041.1 - 4.8 7.2 55.8 0.12 12.4 19.0 5.2 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.12 EER23041.1 - 5.3 7.1 24.2 0.42 10.6 4.9 5.2 4 1 2 6 6 6 0 Protein of unknown function (DUF1664) PK PF00224.21 EER23042.1 - 7.7e-172 570.9 3.5 9.4e-172 570.6 3.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EER23042.1 - 5e-39 133.2 0.0 4.2e-38 130.2 0.0 2.4 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EER23042.1 - 0.00048 19.3 0.7 0.0015 17.7 0.6 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EER23042.1 - 0.014 14.4 0.1 0.12 11.3 0.0 2.1 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.10 EER23043.1 - 1.2e-36 124.4 0.0 1.3e-36 124.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF3506 PF12014.8 EER23044.1 - 1e-50 171.3 0.0 2.5e-50 170.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 EER23044.1 - 9.8e-09 35.0 1.4 2e-08 34.0 1.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER23044.1 - 2.4e-06 27.3 0.2 4.5e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EER23044.1 - 0.021 14.7 0.1 0.035 14.0 0.1 1.3 1 0 0 1 1 1 0 F-box PIP5K PF01504.18 EER23045.1 - 1.6e-35 122.7 0.4 1.5e-26 93.3 0.5 2.6 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EER23045.1 - 9.2e-28 97.1 0.0 1.5e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EER23045.1 - 1.3e-13 50.9 9.1 1.3e-13 50.9 9.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger adh_short_C2 PF13561.6 EER23045.1 - 0.18 11.3 0.1 0.34 10.4 0.1 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Cwf_Cwc_15 PF04889.12 EER23045.1 - 0.23 11.2 11.8 0.079 12.7 0.3 2.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TPP1 PF10341.9 EER23046.1 - 1.6e-20 73.2 0.0 3.2e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD SUR7 PF06687.12 EER23047.1 - 6.4e-48 163.2 0.7 7.7e-48 162.9 0.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family WD40 PF00400.32 EER23048.1 - 1.8e-12 47.6 19.9 0.00023 21.9 0.2 9.1 10 0 0 10 10 10 5 WD domain, G-beta repeat XPG_N PF00752.17 EER23049.1 - 4.9e-35 120.0 0.0 1.2e-34 118.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EER23049.1 - 1.6e-25 89.2 0.6 3.8e-25 88.1 0.0 2.0 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EER23049.1 - 4.3e-05 24.0 0.1 0.00028 21.4 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.16 EER23049.1 - 0.013 15.8 0.0 0.05 13.9 0.0 2.0 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family Dpy19 PF10034.9 EER23049.1 - 0.29 9.3 0.1 0.41 8.8 0.1 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation UIM PF02809.20 EER23049.1 - 2.2 8.4 5.5 0.43 10.6 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Pil1 PF13805.6 EER23050.1 - 5.1e-125 416.3 0.0 6.5e-125 416.0 0.0 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 EER23050.1 - 0.052 13.0 2.0 0.068 12.6 0.7 1.8 1 1 1 2 2 2 0 FAM92 protein Spc7_N PF15402.6 EER23051.1 - 0 1189.0 58.1 0 1188.5 58.1 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EER23051.1 - 6.1e-124 412.9 7.2 6.1e-124 412.9 7.2 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein Ribosomal_S17_N PF16205.5 EER23052.1 - 2.4e-34 117.5 0.4 4e-34 116.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EER23052.1 - 1.6e-27 95.4 0.6 1.6e-27 95.4 0.6 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 TolB_N PF04052.13 EER23053.1 - 0.04 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 TolB amino-terminal domain LSM PF01423.22 EER23054.1 - 7.8e-09 35.1 0.0 1e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EER23054.1 - 0.041 14.0 0.0 0.062 13.5 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Metallophos PF00149.28 EER23055.1 - 1.7e-37 130.0 0.1 2.6e-37 129.3 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EER23055.1 - 2.2e-15 56.8 0.0 3.9e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 EER23056.1 - 8.5e-20 70.7 10.4 0.00023 21.9 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23056.1 - 4.7e-15 55.6 0.1 2.3e-07 31.0 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER23056.1 - 8.1e-05 22.6 0.4 0.018 14.9 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 EER23056.1 - 0.0024 17.7 0.2 0.0024 17.7 0.2 2.7 2 0 0 2 2 2 1 HIRA B motif Ge1_WD40 PF16529.5 EER23056.1 - 0.019 13.9 0.0 38 3.1 0.0 3.8 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EER23056.1 - 0.056 13.4 4.1 20 5.3 0.1 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EER23056.1 - 0.096 12.0 0.0 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Cmc1 PF08583.10 EER23057.1 - 0.0023 17.9 2.7 0.0048 16.9 2.7 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Sugar_tr PF00083.24 EER23059.1 - 1.4e-95 320.8 26.9 1.7e-95 320.5 26.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER23059.1 - 2.1e-16 59.8 32.9 6.4e-16 58.2 33.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Gpr1_Fun34_YaaH PF01184.19 EER23060.1 - 6.7e-84 280.6 21.6 7.9e-84 280.4 21.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ANTH PF07651.16 EER23061.1 - 2.4e-55 187.5 0.1 2.4e-55 187.5 0.1 1.4 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 EER23061.1 - 1.3e-09 38.1 0.0 8.9e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 ENTH domain Peptidase_S49_N PF08496.10 EER23061.1 - 0.19 11.7 1.0 0.36 10.9 1.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Memo PF01875.17 EER23063.1 - 2.1e-62 210.7 0.0 4e-62 209.8 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein Rad4 PF03835.15 EER23064.1 - 5.7e-16 58.5 3.5 1e-15 57.7 3.5 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EER23064.1 - 1.6e-11 44.6 1.3 3.4e-11 43.6 1.3 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily Pex14_N PF04695.13 EER23064.1 - 1.3 9.7 8.0 0.34 11.5 3.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WD40 PF00400.32 EER23065.1 - 1e-08 35.6 7.5 1.9 9.5 0.1 8.7 10 0 0 10 10 10 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23065.1 - 4.3e-08 33.3 1.6 0.12 12.7 0.0 5.9 5 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EER23065.1 - 0.00033 20.3 1.1 0.017 14.7 0.0 3.3 3 1 0 3 3 3 1 PQQ-like domain PD40 PF07676.12 EER23065.1 - 0.0043 16.9 0.0 0.93 9.5 0.1 3.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.14 EER23065.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Lactonase PF10282.9 EER23065.1 - 0.051 12.8 0.0 1.1 8.5 0.0 2.9 3 2 1 4 4 4 0 Lactonase, 7-bladed beta-propeller Cyclin_N PF00134.23 EER23066.1 - 5.4e-36 123.2 0.1 1.1e-35 122.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EER23066.1 - 4.9e-07 29.9 1.9 3.3e-06 27.2 1.9 2.3 1 1 0 1 1 1 1 Cyclin, C-terminal domain Acyl_transf_3 PF01757.22 EER23067.1 - 1.2e-17 64.0 31.1 3e-17 62.7 31.1 1.7 1 1 0 1 1 1 1 Acyltransferase family DUF2975 PF11188.8 EER23067.1 - 0.37 10.7 7.5 2.6 7.9 0.5 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2975) Methyltransf_23 PF13489.6 EER23068.1 - 6.7e-19 68.3 0.0 9.9e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23068.1 - 9.4e-12 45.5 0.0 2.5e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER23068.1 - 2.9e-10 40.7 0.0 5.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER23068.1 - 8.7e-08 32.1 0.0 1.4e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER23068.1 - 5.8e-07 30.2 0.0 3.5e-06 27.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 EER23068.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 EER23068.1 - 0.024 14.0 0.0 0.25 10.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EER23068.1 - 0.026 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EER23068.1 - 0.029 13.7 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EER23068.1 - 0.032 13.5 0.0 0.075 12.3 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 EER23068.1 - 0.073 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.12 EER23068.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_2 PF00891.18 EER23068.1 - 0.11 11.8 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain Amidohydro_2 PF04909.14 EER23069.1 - 7.5e-10 39.1 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EER23069.1 - 3.4e-06 26.6 0.1 6.2e-05 22.5 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family FKBP_C PF00254.28 EER23070.1 - 2.4e-31 107.9 0.0 2.9e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.28 EER23071.1 - 1.1e-14 54.3 0.0 1.6e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain T5orf172 PF10544.9 EER23072.1 - 1.7e-19 70.3 2.2 4.4e-19 68.9 2.2 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EER23072.1 - 1e-16 61.4 2.0 3e-16 59.8 2.0 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Zip PF02535.22 EER23074.1 - 1.6e-67 228.1 3.1 1.9e-67 227.8 3.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter CPP1-like PF11833.8 EER23074.1 - 0.15 11.7 2.4 14 5.2 0.0 2.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Tom37 PF10568.9 EER23075.1 - 2.5e-37 128.0 0.0 3.9e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EER23075.1 - 5.6e-09 35.7 0.1 3.2e-08 33.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EER23075.1 - 0.0031 18.2 0.0 0.0066 17.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain NAPRTase PF04095.16 EER23077.1 - 4.5e-53 180.3 0.0 3e-26 92.5 0.1 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EER23077.1 - 5.4e-37 127.0 0.1 8.6e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF4303 PF14136.6 EER23077.1 - 0.026 14.3 0.1 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) p450 PF00067.22 EER23078.1 - 2.7e-48 164.9 0.0 3.8e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Syntaxin PF00804.25 EER23079.1 - 2.2e-17 63.4 14.9 1.1e-16 61.1 14.9 1.9 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 EER23079.1 - 1.4e-06 28.6 6.5 8.3e-06 26.1 0.3 2.3 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EER23079.1 - 0.0005 20.0 13.4 0.00085 19.3 10.2 3.0 2 1 0 2 2 2 1 SNARE domain Spectrin PF00435.21 EER23079.1 - 0.0019 18.6 5.2 1.5 9.3 0.0 3.3 2 1 1 3 3 3 2 Spectrin repeat HHH_2 PF12826.7 EER23079.1 - 0.025 14.7 0.4 0.1 12.7 0.4 2.0 1 0 0 1 1 1 0 Helix-hairpin-helix motif LMBR1 PF04791.16 EER23079.1 - 0.026 13.4 3.0 0.034 13.1 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4954 PF16314.5 EER23079.1 - 0.027 12.6 4.8 0.03 12.5 4.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) PTA_PTB PF01515.19 EER23079.1 - 0.046 13.0 3.3 0.067 12.5 3.3 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase MCU PF04678.13 EER23079.1 - 0.051 13.7 5.3 0.064 13.4 0.9 2.2 2 0 0 2 2 2 0 Mitochondrial calcium uniporter DUF2207 PF09972.9 EER23079.1 - 0.066 12.0 0.4 0.11 11.3 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) BLOC1_2 PF10046.9 EER23079.1 - 0.069 13.5 5.8 0.98 9.8 0.4 3.3 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 COG2 PF06148.11 EER23079.1 - 0.079 13.0 0.2 0.079 13.0 0.2 2.7 2 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 EER23079.1 - 0.15 12.1 2.8 15 5.7 0.1 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5345 PF17280.2 EER23079.1 - 0.32 11.0 0.1 0.32 11.0 0.1 2.8 3 0 0 3 3 2 0 Family of unknown function (DUF5345) Ferritin PF00210.24 EER23079.1 - 0.34 10.9 4.7 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 Ferritin-like domain FtsK_SpoIIIE PF01580.18 EER23079.1 - 0.4 10.0 4.7 0.31 10.3 2.2 1.9 2 1 1 3 3 3 0 FtsK/SpoIIIE family Vps51 PF08700.11 EER23079.1 - 0.45 10.6 5.0 7.3 6.8 1.7 3.2 2 2 0 2 2 2 0 Vps51/Vps67 TMCO5 PF14992.6 EER23079.1 - 0.58 9.7 7.7 1.7 8.2 7.7 1.9 1 1 0 1 1 1 0 TMCO5 family PBP1_TM PF14812.6 EER23079.1 - 1.4 9.4 6.4 0.49 10.8 1.3 2.7 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SP_C-Propep PF08999.10 EER23079.1 - 1.6 8.5 4.7 3.1 7.6 4.7 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Tweety PF04906.13 EER23079.1 - 2.9 6.4 7.1 0.45 9.1 2.4 1.7 1 1 1 2 2 2 0 Tweety NPV_P10 PF05531.12 EER23079.1 - 5.2 7.6 6.6 9.7 6.7 1.2 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PIN_8 PF18476.1 EER23079.1 - 8.6 6.1 10.3 1.3 8.8 3.9 2.1 1 1 1 2 2 2 0 PIN like domain BolA PF01722.18 EER23080.1 - 2.3e-31 107.9 0.7 3.8e-31 107.2 0.7 1.3 1 0 0 1 1 1 1 BolA-like protein AMP-binding PF00501.28 EER23081.1 - 4.2e-62 210.1 0.0 6.2e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER23081.1 - 1.5e-12 48.3 0.0 2.9e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.18 EER23082.1 - 4.3e-54 182.6 0.4 5.5e-54 182.3 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 EER23083.1 - 1.1e-22 80.0 0.7 2.4e-22 78.9 0.7 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.20 EER23084.1 - 4.3e-27 93.9 1.9 9.2e-27 92.8 1.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EER23084.1 - 4.3e-24 83.8 0.0 6.9e-24 83.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EER23084.1 - 4.4 7.9 9.7 10 6.7 9.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RhoGEF67_u1 PF16615.5 EER23085.1 - 3.2 8.3 9.4 0.2 12.2 2.5 2.3 2 0 0 2 2 2 0 Unstructured region one on RhoGEF 6 and 7 PIN_4 PF13638.6 EER23086.1 - 0.0038 17.5 0.0 0.023 15.0 0.0 2.1 2 0 0 2 2 2 1 PIN domain Rhodanese PF00581.20 EER23087.1 - 5.4e-19 68.7 0.0 2.9e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain zf-ANAPC11 PF12861.7 EER23088.1 - 1.3e-45 153.4 8.9 1.4e-45 153.2 8.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EER23088.1 - 9.1e-22 77.1 10.0 1.2e-21 76.7 10.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EER23088.1 - 2e-08 34.4 15.8 5.8e-07 29.7 15.8 2.5 1 1 1 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EER23088.1 - 6.3e-05 22.9 8.8 0.00089 19.2 9.5 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EER23088.1 - 0.00037 20.3 13.3 0.0014 18.4 13.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER23088.1 - 0.0018 18.1 17.4 0.0032 17.3 14.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER23088.1 - 0.0032 17.3 12.1 0.12 12.3 12.3 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER23088.1 - 0.02 14.9 17.2 0.35 10.9 17.5 2.7 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EER23088.1 - 0.039 13.6 11.8 0.15 11.7 10.7 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EER23088.1 - 0.041 13.7 11.8 2.6 7.9 8.9 2.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EER23088.1 - 0.048 13.5 3.8 0.073 12.9 3.8 1.3 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EER23088.1 - 0.11 12.3 8.9 1 9.2 8.9 2.3 1 1 0 1 1 1 0 RING-like zinc finger MTBP_mid PF14919.6 EER23088.1 - 0.12 11.5 0.1 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 MDM2-binding FANCL_C PF11793.8 EER23088.1 - 0.16 12.2 15.7 1.2 9.4 15.7 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EER23088.1 - 0.57 10.4 13.1 0.35 11.1 9.6 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING RecR PF02132.15 EER23088.1 - 0.65 9.6 6.8 4.8 6.8 0.4 3.1 3 0 0 3 3 3 0 RecR protein zf-RING-like PF08746.11 EER23088.1 - 1.2 9.5 11.9 7.8 6.9 11.9 2.2 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 EER23088.1 - 1.5 8.7 14.6 2.7 8.0 13.2 2.2 1 1 0 1 1 1 0 PHD-finger DZR PF12773.7 EER23088.1 - 2.3 8.3 13.0 2.7 8.1 6.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon RINGv PF12906.7 EER23088.1 - 7.8 6.7 14.8 5.8 7.1 12.2 2.1 1 1 1 2 2 2 0 RING-variant domain CCD PF07860.11 EER23089.1 - 0.047 13.7 0.3 0.093 12.8 0.3 1.5 1 0 0 1 1 1 0 WisP family C-Terminal Region TraG_N PF07916.11 EER23089.1 - 0.69 8.7 3.6 4.4 6.1 0.2 2.1 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Kinesin PF00225.23 EER23090.1 - 5.1e-109 364.2 0.3 1.1e-108 363.1 0.3 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EER23090.1 - 1.4e-24 86.7 0.2 9.5e-24 84.0 0.0 2.6 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 EER23090.1 - 9.2e-05 22.8 0.7 9.2e-05 22.8 0.7 5.0 3 2 1 4 4 4 1 Kinesin-associated microtubule-binding DUF948 PF06103.11 EER23090.1 - 0.012 15.8 24.3 0.27 11.5 0.2 6.0 4 2 2 6 6 6 0 Bacterial protein of unknown function (DUF948) GLTP PF08718.11 EER23090.1 - 6.8 7.0 9.1 0.31 11.3 0.9 3.0 2 1 0 2 2 2 0 Glycolipid transfer protein (GLTP) UPF0183 PF03676.14 EER23091.1 - 1.7e-56 192.2 0.0 9.5e-39 133.8 0.0 2.8 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) tRNA-synt_1 PF00133.22 EER23092.1 - 9.8e-168 559.1 0.0 1.3e-167 558.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EER23092.1 - 9.8e-21 73.9 0.3 9.1e-14 51.0 0.0 3.7 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EER23092.1 - 1.4e-19 70.6 0.0 3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 EER23092.1 - 0.00026 20.8 0.9 0.00057 19.7 0.9 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 EER23092.1 - 0.011 15.2 0.0 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EER23092.1 - 0.055 13.0 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Bac_rhodopsin PF01036.18 EER23093.1 - 1.9e-37 129.0 22.6 2.3e-37 128.7 22.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein YibE_F PF07907.11 EER23093.1 - 0.00055 19.5 10.1 0.00055 19.5 10.1 2.1 2 0 0 2 2 2 2 YibE/F-like protein DUF3810 PF12725.7 EER23093.1 - 6 6.1 11.9 0.84 8.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) RPEL PF02755.15 EER23094.1 - 1.2e-27 94.8 16.3 7.6e-09 35.0 0.7 3.6 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 EER23094.1 - 0.0031 18.0 0.1 0.069 13.7 0.0 2.0 1 1 1 2 2 2 1 PPIC-type PPIASE domain CCT_2 PF09425.10 EER23094.1 - 0.022 14.7 4.3 0.47 10.4 0.2 2.5 2 0 0 2 2 2 0 Divergent CCT motif UPF0258 PF06789.12 EER23094.1 - 0.096 12.8 1.3 1.1 9.4 0.2 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) Translin PF01997.16 EER23095.1 - 8.9e-74 247.9 0.0 1.1e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 Translin family Syntaxin_2 PF14523.6 EER23095.1 - 0.034 14.5 0.0 3.2 8.2 0.0 2.9 2 1 0 2 2 2 0 Syntaxin-like protein Fungal_trans PF04082.18 EER23096.1 - 2.8e-16 59.3 1.7 6.6e-16 58.1 1.7 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER23096.1 - 3e-06 27.3 12.3 5.3e-06 26.5 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans PF05007.13 EER23097.1 - 1.2e-75 254.7 11.3 1.2e-75 254.7 11.3 1.8 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EER23097.1 - 4.6e-13 49.0 3.7 4.6e-13 49.0 3.7 2.2 2 1 0 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EER23097.1 - 0.00018 21.3 18.4 0.00018 21.3 18.4 3.0 2 1 0 2 2 2 1 Glycosyltransferase family 87 F-box-like PF12937.7 EER23098.1 - 0.00095 19.0 0.0 0.0049 16.7 0.0 2.3 1 1 0 1 1 1 1 F-box-like AMP-binding PF00501.28 EER23099.1 - 5.8e-60 203.1 0.0 7.4e-60 202.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER23099.1 - 1.1e-11 45.5 0.0 2.9e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain eIF-5a PF01287.20 EER23099.1 - 0.019 15.0 0.0 0.92 9.7 0.0 3.0 3 0 0 3 3 3 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold ECH_1 PF00378.20 EER23100.1 - 1.2e-26 93.6 0.0 1.4e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER23100.1 - 5.2e-12 45.9 0.0 6e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 EER23101.1 - 9.1e-14 51.1 0.0 1.4e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER23101.1 - 0.0028 17.7 13.0 0.0047 17.0 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SQS_PSY PF00494.19 EER23102.1 - 3e-39 135.1 0.0 4.6e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase Cbl_N2 PF02761.14 EER23102.1 - 0.37 11.5 2.4 21 5.9 0.1 3.3 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain DnaJ-X PF14308.6 EER23103.1 - 3.1e-79 265.3 7.0 3.1e-79 265.3 7.0 3.1 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EER23103.1 - 3.4e-27 94.3 0.7 1.2e-26 92.6 0.7 2.0 1 0 0 1 1 1 1 DnaJ domain DUF2924 PF11149.8 EER23103.1 - 0.48 10.8 9.6 26 5.2 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2924) SUIM_assoc PF16619.5 EER23103.1 - 0.53 10.4 5.6 0.54 10.4 0.0 3.7 4 2 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 HNH_2 PF13391.6 EER23105.1 - 6.5e-19 67.8 0.9 1.6e-18 66.5 0.5 1.9 2 0 0 2 2 2 1 HNH endonuclease APG6 PF04111.12 EER23106.1 - 1e-72 243.9 0.0 1.5e-72 243.3 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EER23106.1 - 4.1e-30 105.0 0.0 6.4e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region Selenoprotein_S PF06936.11 EER23106.1 - 0.093 12.5 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF1918 PF08940.11 EER23108.1 - 0.00089 18.8 0.1 2.1 8.0 0.0 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1918) I-set PF07679.16 EER23108.1 - 0.009 16.1 0.0 16 5.7 0.0 4.5 4 0 0 4 4 4 1 Immunoglobulin I-set domain Nrap_D4 PF17405.2 EER23109.1 - 4.7e-55 186.2 0.0 7.9e-55 185.5 0.0 1.3 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 EER23109.1 - 1.3e-49 168.1 0.1 2e-49 167.5 0.1 1.3 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EER23109.1 - 1.5e-46 158.0 0.2 3.3e-46 156.8 0.0 1.7 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 EER23109.1 - 2.7e-38 131.6 0.0 5.6e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 EER23109.1 - 5.5e-34 117.4 0.9 8.4e-34 116.8 0.9 1.3 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 EER23109.1 - 8.4e-26 90.8 0.0 1.7e-25 89.8 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 6 Cys_Met_Meta_PP PF01053.20 EER23110.1 - 1.2e-29 103.1 0.0 1.5e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EER23110.1 - 0.011 14.9 0.0 0.02 14.1 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II MRP-L20 PF12824.7 EER23112.1 - 1.3e-57 194.6 5.2 1.4e-57 194.4 5.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 EER23112.1 - 0.019 15.5 2.7 0.12 13.0 1.1 2.8 2 1 0 2 2 2 0 Homeodomain-like domain Peptidase_M20 PF01546.28 EER23113.1 - 3e-34 118.5 0.0 3.8e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EER23113.1 - 2.4e-13 49.9 0.0 4.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EER23113.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 SMC_N PF02463.19 EER23114.1 - 2e-25 89.5 0.0 7e-25 87.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EER23114.1 - 2.8e-10 40.5 3.1 2.8e-10 40.5 3.1 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EER23114.1 - 1.6e-09 38.6 21.5 1.6e-09 38.6 21.5 4.8 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EER23114.1 - 8.9e-09 35.6 3.3 1.9e-05 24.7 0.1 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system FAM76 PF16046.5 EER23114.1 - 0.00039 19.9 10.9 0.00039 19.9 10.9 3.9 3 1 0 4 4 4 1 FAM76 protein AAA_29 PF13555.6 EER23114.1 - 0.00078 19.1 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EER23114.1 - 0.027 14.7 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 EER23114.1 - 0.12 11.0 58.4 0.023 13.3 2.7 5.8 3 2 2 5 5 5 0 AAA domain ABC_tran PF00005.27 EER23114.1 - 0.19 12.3 0.1 0.19 12.3 0.1 4.9 3 2 0 3 3 3 0 ABC transporter DEAD PF00270.29 EER23115.1 - 1.8e-42 145.1 0.1 2.7e-42 144.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER23115.1 - 3.3e-28 98.2 1.1 4e-27 94.8 0.5 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER23115.1 - 0.002 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EER23115.1 - 0.011 15.1 0.1 0.025 13.9 0.1 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Mito_carr PF00153.27 EER23116.1 - 2.6e-37 126.6 8.4 1.5e-15 56.9 0.2 4.9 4 1 1 5 5 5 5 Mitochondrial carrier protein PCRF PF03462.18 EER23117.1 - 7.2e-50 169.5 0.0 2e-49 168.1 0.0 1.7 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EER23117.1 - 2e-31 108.3 1.6 4.2e-31 107.3 1.6 1.5 1 0 0 1 1 1 1 RF-1 domain JAKMIP_CC3 PF16034.5 EER23117.1 - 0.1 12.5 2.2 0.99 9.3 0.2 2.2 2 0 0 2 2 2 0 JAKMIP CC3 domain DNAJ_related PF12339.8 EER23117.1 - 0.18 12.0 0.0 0.42 10.8 0.0 1.5 1 0 0 1 1 1 0 DNA-J related protein DUF3723 PF12520.8 EER23118.1 - 2.1e-130 435.8 1.8 3.2e-130 435.2 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) APH PF01636.23 EER23119.1 - 5.3e-09 36.3 0.0 1.5e-08 34.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER23119.1 - 0.055 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EER23119.1 - 0.25 10.6 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DnaJ PF00226.31 EER23120.1 - 8.6e-22 77.0 1.7 8.6e-22 77.0 1.7 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 EER23120.1 - 6.4e-17 60.6 0.0 5.8e-06 25.9 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EER23120.1 - 1.4e-15 57.1 3.5 0.00027 21.0 0.0 5.0 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EER23120.1 - 5.5e-14 51.1 0.6 0.00085 19.3 0.0 7.1 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EER23120.1 - 1.6e-12 47.1 3.6 0.044 14.6 0.0 6.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER23120.1 - 2.8e-11 42.7 0.9 0.0072 16.5 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EER23120.1 - 6.9e-10 38.9 2.0 0.7 10.7 0.0 7.9 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EER23120.1 - 1.2e-09 38.5 0.4 0.0067 16.9 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EER23120.1 - 1e-06 28.7 0.0 0.0031 17.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER23120.1 - 2.2e-06 27.3 0.1 1.7 8.4 0.0 5.0 5 1 1 6 6 6 1 TPR repeat TPR_16 PF13432.6 EER23120.1 - 4.2e-06 27.3 8.1 0.0034 18.0 0.0 5.7 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER23120.1 - 0.00022 21.0 0.0 0.89 9.7 0.0 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EER23120.1 - 0.0007 19.8 1.9 12 6.2 0.0 5.2 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 PknG_TPR PF16918.5 EER23120.1 - 0.00095 18.0 0.0 0.0051 15.6 0.0 2.2 2 1 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_12 PF13424.6 EER23120.1 - 0.0024 18.1 5.1 0.44 10.9 0.0 4.6 4 2 0 4 4 4 1 Tetratricopeptide repeat RPT PF13446.6 EER23120.1 - 0.015 15.2 0.2 0.26 11.3 0.0 2.9 3 1 0 3 3 3 0 A repeated domain in UCH-protein IR1-M PF12185.8 EER23120.1 - 0.03 14.3 0.0 0.093 12.7 0.0 1.9 1 0 0 1 1 1 0 Nup358/RanBP2 E3 ligase domain Alkyl_sulf_dimr PF14863.6 EER23120.1 - 0.049 14.1 0.0 2.8 8.4 0.1 2.6 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation HEPN PF05168.14 EER23120.1 - 0.19 11.9 3.9 14 5.9 1.2 2.9 2 0 0 2 2 2 0 HEPN domain PCMT PF01135.19 EER23121.1 - 1.6e-61 207.7 0.0 3.3e-61 206.7 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EER23121.1 - 2.1e-06 27.6 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23121.1 - 1.4e-05 25.7 0.0 2.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EER23121.1 - 0.00016 21.7 0.0 0.00024 21.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER23121.1 - 0.0028 17.5 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EER23121.1 - 0.0089 15.6 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.12 EER23121.1 - 0.021 15.5 0.0 0.033 14.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EER23121.1 - 0.021 15.6 0.0 0.037 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EER23121.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.6 EER23121.1 - 0.12 13.4 0.0 0.42 11.7 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Pkinase PF00069.25 EER23122.1 - 7.8e-42 143.5 0.0 1.2e-38 133.0 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER23122.1 - 4.3e-08 32.7 0.0 0.0015 17.8 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EER23122.1 - 0.0071 16.3 0.2 0.029 14.3 0.2 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EER23122.1 - 0.054 12.3 0.0 0.073 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EER23122.1 - 0.22 10.8 0.0 21 4.3 0.0 2.3 2 1 0 2 2 2 0 Kinase-like Cnd1_N PF12922.7 EER23123.1 - 6.5e-59 198.5 0.7 1.4e-58 197.4 0.7 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EER23123.1 - 3.8e-48 163.6 2.3 4.7e-44 150.3 0.8 3.1 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EER23123.1 - 4.8e-09 35.7 7.4 0.06 13.6 0.0 6.7 6 1 1 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EER23123.1 - 3.6e-08 33.7 4.7 0.0006 20.1 0.0 4.9 4 1 2 6 6 6 3 HEAT repeats RTP1_C1 PF10363.9 EER23123.1 - 3.2e-06 27.3 1.0 0.076 13.2 0.0 4.3 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EER23123.1 - 0.0031 16.8 5.0 0.0095 15.2 1.7 3.0 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 EER23123.1 - 0.014 15.9 9.7 0.29 11.7 0.1 5.3 6 0 0 6 6 6 0 HEAT-like repeat Oxysterol_BP PF01237.18 EER23124.1 - 1.7e-51 175.2 0.1 2e-49 168.4 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein OTU PF02338.19 EER23125.1 - 2.9e-08 34.3 0.0 5.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.8 EER23125.1 - 0.026 15.0 0.0 0.07 13.6 0.0 1.8 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Bromodomain PF00439.25 EER23126.1 - 1.6e-41 140.2 3.2 2.5e-21 75.6 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EER23126.1 - 1.6e-19 69.9 0.5 3.5e-19 68.9 0.5 1.6 1 0 0 1 1 1 1 BAH domain HTH_32 PF13565.6 EER23126.1 - 2.5 8.8 9.8 3.7 8.2 2.0 3.5 3 0 0 3 3 3 0 Homeodomain-like domain DNA_pol_phi PF04931.13 EER23126.1 - 3 5.8 7.5 5.4 5.0 7.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EER23126.1 - 8 5.7 6.8 22 4.2 6.8 1.7 1 0 0 1 1 1 0 NOA36 protein zf-CCCH PF00642.24 EER23127.1 - 2.7e-11 43.1 9.3 2.5e-06 27.3 1.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EER23127.1 - 7e-10 38.5 9.3 3.7e-06 26.6 2.2 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EER23127.1 - 7.7e-09 35.3 16.4 4.2e-05 23.4 1.8 2.3 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EER23127.1 - 1.8e-08 35.0 5.0 0.00044 20.9 0.2 2.6 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EER23127.1 - 0.00018 21.7 0.1 0.00034 20.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EER23127.1 - 0.0072 16.8 14.1 0.18 12.3 3.2 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Sel1 PF08238.12 EER23128.1 - 3.1e-17 62.6 19.8 3.1e-06 27.7 0.1 6.8 6 1 0 6 6 6 5 Sel1 repeat TPR_1 PF00515.28 EER23128.1 - 0.049 13.5 4.4 0.11 12.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EER23128.1 - 0.57 10.4 7.3 1.6 9.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.6 EER23129.1 - 4.6e-56 189.6 0.0 8.8e-56 188.7 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EER23129.1 - 1e-49 168.5 0.1 3.7e-49 166.7 0.1 1.9 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EER23129.1 - 0.002 18.2 0.0 1.5 8.8 0.1 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit HBB PF06777.11 EER23129.1 - 0.0043 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain AAA_22 PF13401.6 EER23129.1 - 0.016 15.5 0.0 0.4 10.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Ribosomal_L27A PF00828.19 EER23130.1 - 2.7e-22 79.8 0.0 3.8e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RTC4 PF14474.6 EER23130.1 - 0.11 12.7 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 RTC4-like domain Ectatomin PF06457.11 EER23131.1 - 0.1 12.5 2.8 3.1 7.8 0.0 2.9 3 1 0 3 3 3 0 Ectatomin DUF3328 PF11807.8 EER23132.1 - 5.5e-41 140.8 2.7 6.7e-41 140.5 2.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Abhydrolase_6 PF12697.7 EER23133.1 - 0.00021 22.0 0.0 0.0003 21.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER23133.1 - 0.00037 19.8 0.0 0.00059 19.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PLDc PF00614.22 EER23135.1 - 1.4e-16 59.9 0.2 2.7e-07 30.5 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EER23135.1 - 1.6e-13 50.7 0.0 5.6e-07 29.5 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EER23135.1 - 2.5e-09 37.1 0.1 1.1e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 PX domain DUF4614 PF15391.6 EER23135.1 - 2.6 8.0 0.0 2.6 8.0 0.0 4.2 6 0 0 6 6 6 0 Domain of unknown function (DUF4614) DNase_NucA_NucB PF14040.6 EER23136.1 - 2.9e-15 56.6 0.6 2.9e-15 56.6 0.6 2.6 1 1 0 2 2 2 1 Deoxyribonuclease NucA/NucB AA_permease PF00324.21 EER23137.1 - 1.5e-62 211.8 29.0 4.3e-62 210.3 29.0 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER23137.1 - 1.2e-25 90.3 25.6 1.5e-25 89.9 25.6 1.2 1 0 0 1 1 1 1 Amino acid permease Peptidase_S41 PF03572.18 EER23139.1 - 8.7e-08 31.9 0.0 1.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Ras PF00071.22 EER23140.1 - 6.8e-39 133.1 0.0 3.6e-37 127.4 0.0 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EER23140.1 - 6.5e-11 42.5 0.1 2.8e-10 40.4 0.0 2.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER23140.1 - 0.0016 17.9 0.0 0.02 14.4 0.0 2.1 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EER23140.1 - 0.0034 17.5 0.0 0.0083 16.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.18 EER23140.1 - 0.27 10.9 1.1 0.54 10.0 0.1 2.0 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family QRPTase_C PF01729.19 EER23141.1 - 5.3e-49 166.2 0.0 1.3e-47 161.8 0.0 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EER23141.1 - 3.4e-22 78.3 0.0 7.6e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Aldose_epim PF01263.20 EER23142.1 - 6.4e-56 189.8 0.1 7.8e-56 189.6 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.18 EER23144.1 - 4e-08 33.2 16.1 6e-08 32.7 16.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 EER23144.1 - 0.11 13.0 2.5 0.2 12.1 2.5 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Mto2_bdg PF12808.7 EER23145.1 - 1.8e-27 95.3 32.0 4.1e-20 71.8 17.7 12.0 15 1 1 16 16 16 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Cnn_1N PF07989.11 EER23145.1 - 2.9e-23 81.8 13.2 2.9e-23 81.8 13.2 11.4 10 2 1 12 12 12 3 Centrosomin N-terminal motif 1 HMMR_C PF15908.5 EER23145.1 - 0.0044 17.3 0.2 0.0044 17.3 0.2 8.1 7 2 5 12 12 12 2 Hyaluronan mediated motility receptor C-terminal BRE1 PF08647.11 EER23145.1 - 0.0052 16.8 15.2 0.0052 16.8 15.2 9.7 8 2 0 9 9 9 2 BRE1 E3 ubiquitin ligase PH_9 PF15410.6 EER23146.1 - 4.2e-19 69.1 0.1 4.8e-18 65.7 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Sec7 PF01369.20 EER23146.1 - 5.9e-16 58.7 0.0 7e-15 55.2 0.0 2.2 1 1 1 2 2 2 1 Sec7 domain UNC-50 PF05216.13 EER23147.1 - 1.2e-64 217.9 2.1 1.8e-64 217.4 2.1 1.1 1 0 0 1 1 1 1 UNC-50 family PP28 PF10252.9 EER23149.1 - 6.6e-30 103.4 15.3 6.6e-30 103.4 15.3 3.5 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 EFTUD2 PF16004.5 EER23149.1 - 0.051 14.2 2.0 0.051 14.2 2.0 3.1 2 1 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Nop53 PF07767.11 EER23149.1 - 0.96 8.8 45.6 1.2 8.4 11.3 2.0 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) MFS_1 PF07690.16 EER23151.1 - 1.8e-21 76.5 52.4 1.1e-19 70.6 44.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LETM1 PF07766.13 EER23152.1 - 7.7e-09 35.3 1.4 4.5e-06 26.2 0.4 2.4 2 1 0 2 2 2 1 LETM1-like protein PAP_assoc PF03828.19 EER23153.1 - 0.0043 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EER23153.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Glyco_transf_20 PF00982.21 EER23154.1 - 1.6e-152 508.5 0.0 2.4e-152 508.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EER23154.1 - 2e-82 275.8 0.0 3.4e-82 275.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EER23154.1 - 3.5e-06 27.0 0.0 0.0045 16.7 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EER23154.1 - 0.18 12.1 0.1 14 5.9 0.0 2.5 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.25 EER23155.1 - 5.9e-15 55.5 0.0 1.8e-14 54.0 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER23155.1 - 1.6e-11 44.5 0.0 2.6e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER23155.1 - 4.3e-11 42.8 0.0 6.2e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER23155.1 - 2.4e-07 30.6 0.0 1.4e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.6 EER23155.1 - 0.00053 20.1 0.1 0.0015 18.6 0.0 1.6 1 1 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EER23155.1 - 0.0022 18.2 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HAMP_N3 PF18575.1 EER23155.1 - 0.017 14.7 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 HAMP N-terminal domain 3 Acetyltransf_15 PF17013.5 EER23155.1 - 0.037 13.5 0.0 0.12 11.8 0.0 1.8 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_3 PF13302.7 EER23155.1 - 0.061 14.0 0.0 0.081 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EER23155.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase N_BRCA1_IG PF16158.5 EER23156.1 - 4.3e-33 114.1 0.0 1.5e-32 112.3 0.0 2.0 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EER23156.1 - 5.9e-21 74.0 51.8 8.6e-07 28.7 4.5 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 EER23156.1 - 0.0021 18.3 44.1 0.25 11.7 6.3 4.6 4 0 0 4 4 4 4 C1 domain Rubredoxin_2 PF18073.1 EER23156.1 - 0.41 10.4 7.6 0.31 10.8 3.9 2.8 2 0 0 2 2 2 0 Rubredoxin metal binding domain Btz PF09405.10 EER23157.1 - 1e-27 97.0 1.5 3.1e-27 95.4 1.5 1.8 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding SBE2 PF17076.5 EER23157.1 - 1.5 6.9 3.8 1.9 6.6 3.8 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation RRM_1 PF00076.22 EER23158.1 - 3.1e-22 78.2 0.0 4.1e-13 48.9 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER23158.1 - 2.4e-05 24.3 0.0 0.2 11.8 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif Pro-MCH PF05824.12 EER23158.1 - 0.019 14.8 0.0 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) Ino80_Iec3 PF14612.6 EER23159.1 - 1.2e-70 238.9 0.0 1.8e-70 238.3 0.0 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Transferase PF02458.15 EER23162.1 - 6.2e-22 77.8 0.0 2.2e-20 72.7 0.0 2.0 2 0 0 2 2 2 2 Transferase family FAD_binding_4 PF01565.23 EER23163.1 - 6.7e-21 74.5 0.4 1.2e-20 73.6 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EER23163.1 - 1.9e-10 40.7 0.1 4.4e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ECR1_N PF14382.6 EER23164.1 - 6.6e-15 54.6 0.9 1.7e-14 53.3 0.4 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EER23164.1 - 0.00011 22.5 0.4 0.00024 21.4 0.4 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EER23164.1 - 0.021 15.4 0.3 1.8 9.2 0.1 2.8 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Oxysterol_BP PF01237.18 EER23165.1 - 2.9e-119 398.2 0.0 5.5e-119 397.3 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EER23165.1 - 6.9e-39 132.0 0.1 1.6e-38 130.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EER23165.1 - 3.5e-05 24.3 0.8 6.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 PH domain MFS_1 PF07690.16 EER23167.1 - 6.2e-46 156.9 34.9 6.2e-46 156.9 34.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER23167.1 - 4e-08 32.5 8.1 4e-08 32.5 8.1 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 EER23167.1 - 6.8 4.8 14.1 1.3 7.2 1.5 2.7 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPMT PF05724.11 EER23168.1 - 3.4e-29 102.1 0.0 8.4e-29 100.8 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 EER23168.1 - 0.00012 22.6 0.0 0.00024 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER23168.1 - 0.00016 21.5 0.0 0.00037 20.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23168.1 - 0.0014 19.3 0.0 0.0027 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EER23168.1 - 0.029 14.7 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase N2227 PF07942.12 EER23168.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.19 EER23169.1 - 2e-18 67.1 0.0 1.7e-17 64.1 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EER23169.1 - 2.8e-05 23.7 0.0 0.12 11.7 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain DUF4407 PF14362.6 EER23169.1 - 0.037 13.4 8.1 0.058 12.7 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4551 PF15087.6 EER23169.1 - 9.9 4.9 9.8 13 4.5 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) adh_short_C2 PF13561.6 EER23170.1 - 3.6e-50 170.7 0.0 4.2e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER23170.1 - 6.4e-46 156.3 0.0 8.5e-46 155.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER23170.1 - 2.2e-08 34.2 0.0 4.8e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 EER23170.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 EER23170.1 - 0.084 12.2 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Trehalase PF01204.18 EER23172.1 - 8.2e-193 641.9 0.0 9.7e-193 641.6 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EER23172.1 - 1.1e-17 63.4 0.1 1.8e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain DUF3879 PF12995.7 EER23172.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) RHH_4 PF13467.6 EER23172.1 - 0.046 13.6 0.0 17 5.3 0.0 3.2 4 0 0 4 4 4 0 Ribbon-helix-helix domain Amidase PF01425.21 EER23173.1 - 8.1e-21 74.5 0.1 3.6e-16 59.2 0.0 2.1 1 1 1 2 2 2 2 Amidase Stig1 PF04885.13 EER23174.1 - 3.2e-21 76.3 111.4 1.2e-06 29.1 14.9 5.9 1 1 4 5 5 5 5 Stigma-specific protein, Stig1 ICL PF00463.21 EER23175.1 - 3.9e-302 1002.4 2.4 4.5e-302 1002.2 2.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EER23175.1 - 1.1e-11 44.6 1.6 2.2e-11 43.7 0.0 2.0 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.18 EER23176.1 - 3.7e-20 72.1 1.2 8.2e-20 70.9 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EER23176.1 - 0.0026 18.1 13.0 0.019 15.4 2.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER23176.1 - 0.76 10.8 11.2 0.25 12.3 1.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Ank_4 PF13637.6 EER23177.1 - 1.6e-17 63.6 0.1 0.0013 19.3 0.1 5.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER23177.1 - 3.1e-12 46.9 2.1 2.1e-06 28.3 0.4 3.5 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER23177.1 - 6.7e-08 32.7 2.4 0.14 12.5 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EER23177.1 - 3.1e-07 30.6 0.0 0.035 14.5 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EER23177.1 - 5e-07 29.5 0.0 0.47 11.2 0.0 5.7 5 1 0 5 5 5 1 Ankyrin repeat F-box-like PF12937.7 EER23177.1 - 3.3e-05 23.7 0.1 6.7e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER23178.1 - 0.0072 16.2 0.2 0.028 14.3 0.2 2.0 1 0 0 1 1 1 1 F-box domain GCHY-1 PF02649.14 EER23178.1 - 0.017 14.6 0.5 0.027 14.0 0.5 1.2 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 F-box_4 PF15966.5 EER23178.1 - 0.021 14.7 0.0 0.056 13.3 0.0 1.8 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 EER23178.1 - 0.088 12.7 0.1 0.088 12.7 0.1 1.9 2 0 0 2 2 2 0 F-box-like G_glu_transpept PF01019.21 EER23179.1 - 5.4e-142 474.2 0.0 6.1e-142 474.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.25 EER23180.1 - 4.6e-67 226.1 0.0 5.8e-67 225.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23180.1 - 3.9e-30 105.0 0.0 5.9e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EER23180.1 - 0.022 13.7 0.0 0.041 12.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EER23180.1 - 0.056 13.4 0.1 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EER23180.1 - 0.057 12.8 0.1 0.12 11.7 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pam16 PF03656.13 EER23181.1 - 2.2e-06 27.7 0.2 4.1e-06 26.8 0.2 1.5 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 EER23181.1 - 5.7e-05 23.2 0.0 8.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 EER23181.1 - 0.029 14.0 2.1 0.029 14.0 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.20 EER23182.1 - 3.9e-28 97.5 5.0 3.9e-28 97.5 5.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e zf-C2H2 PF00096.26 EER23184.1 - 0.011 16.1 3.7 0.036 14.5 3.7 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Corazonin PF17308.2 EER23184.1 - 0.11 12.9 10.8 0.37 11.2 10.8 1.9 1 0 0 1 1 1 0 Pro-corazonin Menin PF05053.13 EER23184.1 - 0.39 9.0 8.4 0.62 8.4 8.4 1.4 1 0 0 1 1 1 0 Menin zf-C2H2_4 PF13894.6 EER23184.1 - 0.5 11.3 3.3 1.7 9.7 3.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger SnoaL PF07366.12 EER23185.1 - 0.005 16.6 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EER23185.1 - 0.016 15.9 0.0 0.043 14.5 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Methyltransf_16 PF10294.9 EER23186.1 - 2.8e-05 23.9 0.0 0.00091 19.0 0.0 2.1 2 0 0 2 2 2 1 Lysine methyltransferase GPW_gp25 PF04965.14 EER23186.1 - 0.038 13.8 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Gene 25-like lysozyme FAM176 PF14851.6 EER23186.1 - 1.9 8.2 6.4 1.3 8.6 3.8 2.0 2 0 0 2 2 2 0 FAM176 family Methyltransf_31 PF13847.6 EER23187.1 - 1e-12 48.1 0.0 2.8e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23187.1 - 1.2e-07 32.3 0.0 1.5e-06 28.8 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER23187.1 - 1.2e-06 28.4 0.0 2.3e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER23187.1 - 1.6e-05 25.4 0.4 0.00021 21.9 0.4 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER23187.1 - 5.5e-05 23.9 0.1 0.00013 22.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EER23187.1 - 0.0018 17.9 0.0 0.0043 16.7 0.1 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW FAM176 PF14851.6 EER23187.1 - 0.026 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 FAM176 family PAP_central PF04928.17 EER23187.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain MTS PF05175.14 EER23187.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain FeoA PF04023.14 EER23187.1 - 0.17 12.2 0.4 5 7.4 0.0 2.2 2 0 0 2 2 2 0 FeoA domain PBP1_TM PF14812.6 EER23187.1 - 6 7.3 6.8 0.89 10.0 2.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DSPc PF00782.20 EER23188.1 - 1.1e-24 86.7 0.0 3.3e-22 78.7 0.0 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Aminotran_3 PF00202.21 EER23189.1 - 7.9e-53 179.6 0.0 1.2e-52 179.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III FMN_bind_2 PF04299.12 EER23191.1 - 8.3e-58 194.8 0.0 9.8e-58 194.6 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Hemopexin PF00045.19 EER23193.1 - 1.1e-12 47.6 15.9 0.0014 18.5 0.3 5.1 3 3 1 4 4 4 4 Hemopexin CxC3 PF18804.1 EER23193.1 - 0.0002 21.2 0.0 0.9 9.4 0.0 3.0 2 1 1 3 3 3 2 CxC3 like cysteine cluster associated with KDZ transposases DUF3341 PF11821.8 EER23193.1 - 0.15 11.7 0.0 1 9.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Epimerase PF01370.21 EER23194.1 - 2.3e-17 63.3 0.0 6.4e-17 61.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EER23194.1 - 6.1e-12 45.1 0.0 9e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EER23194.1 - 4.6e-11 42.4 0.0 1.9e-10 40.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EER23194.1 - 1e-09 38.2 0.0 2.4e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EER23194.1 - 2.8e-09 37.1 0.0 4.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EER23194.1 - 6.2e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EER23194.1 - 0.00021 20.6 0.0 0.0003 20.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EER23194.1 - 0.00024 20.6 0.0 0.00057 19.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EER23194.1 - 0.00035 19.8 0.0 0.0023 17.1 0.0 2.1 2 1 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.13 EER23194.1 - 0.00096 18.8 0.0 0.016 14.8 0.0 2.1 2 1 0 2 2 2 1 NmrA-like family SdpI PF13630.6 EER23194.1 - 0.19 11.9 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 SdpI/YhfL protein family DSBA PF01323.20 EER23195.1 - 3.9e-35 121.4 0.0 4.6e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EER23195.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin Zn_clus PF00172.18 EER23198.1 - 6.6e-09 35.8 7.6 1.6e-08 34.5 7.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EER23198.1 - 0.00076 18.6 0.0 0.002 17.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain KH_1 PF00013.29 EER23199.1 - 8.9e-41 137.6 9.0 3.7e-17 61.9 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EER23199.1 - 8.4e-10 38.4 9.8 0.0039 17.0 0.5 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 EER23199.1 - 1.7e-08 34.2 4.9 0.042 13.7 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EER23199.1 - 0.00014 21.9 6.0 0.056 13.5 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain ADH_N PF08240.12 EER23200.1 - 3.3e-30 104.2 0.6 5.9e-30 103.4 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER23200.1 - 1.6e-17 63.7 0.0 2.5e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EER23200.1 - 0.00033 20.2 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 EER23200.1 - 0.001 18.9 0.1 0.0024 17.8 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.6 EER23200.1 - 0.0096 17.0 0.0 0.017 16.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_1 PF00583.25 EER23201.1 - 2.3e-19 69.8 0.0 3.1e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER23201.1 - 1e-12 48.1 0.0 1.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER23201.1 - 4.9e-12 46.1 0.0 7.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER23201.1 - 8.1e-11 41.7 0.1 1.3e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EER23201.1 - 2.7e-08 34.6 0.0 3.4e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER23201.1 - 5.8e-07 29.6 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EER23201.1 - 4.5e-06 26.4 0.0 7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER23201.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EER23201.1 - 0.00018 21.7 0.0 0.0003 21.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EER23201.1 - 0.0049 16.5 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase Acetyltransf_15 PF17013.5 EER23201.1 - 0.038 13.5 0.0 0.078 12.4 0.0 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_13 PF13880.6 EER23201.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase KH_1 PF00013.29 EER23202.1 - 0.018 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 KH domain PPR_3 PF13812.6 EER23202.1 - 0.035 14.2 0.4 0.88 9.7 0.0 2.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain DUF4476 PF14771.6 EER23203.1 - 0.16 12.3 0.1 0.31 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Mis14 PF08641.12 EER23204.1 - 1.7e-24 86.7 0.2 4.3e-24 85.3 0.2 1.7 2 0 0 2 2 2 1 Kinetochore protein Mis14 like CRAL_TRIO PF00650.20 EER23205.1 - 9e-37 126.2 0.0 1.3e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EER23205.1 - 1.7e-08 34.5 0.2 4.4e-08 33.2 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EER23205.1 - 0.001 19.3 0.0 0.0018 18.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.19 EER23207.1 - 1.5e-58 198.0 0.1 4.4e-58 196.4 0.0 1.9 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EER23207.1 - 2e-30 105.7 6.5 2e-30 105.7 6.5 2.8 3 0 0 3 3 3 1 RasGAP C-terminus DUF1647 PF07801.11 EER23207.1 - 0.29 10.9 2.0 0.41 10.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) Fibin PF15819.5 EER23207.1 - 0.81 9.4 8.3 0.089 12.5 1.0 3.0 4 0 0 4 4 4 0 Fin bud initiation factor homologue DNA_pol_A_exo1 PF01612.20 EER23208.1 - 5.4e-39 133.7 0.2 1.3e-38 132.5 0.2 1.7 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.12 EER23208.1 - 7.4e-30 103.5 0.5 2.1e-29 102.0 0.3 2.0 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 EER23208.1 - 1.8e-10 40.6 0.0 3.9e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Myb_DNA-bind_6 PF13921.6 EER23210.1 - 0.035 14.4 0.1 0.052 13.8 0.1 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Baculo_PEP_C PF04513.12 EER23211.1 - 0.0011 19.0 0.1 0.002 18.2 0.1 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus HsbA PF12296.8 EER23211.1 - 0.05 14.0 0.3 0.081 13.4 0.3 1.3 1 0 0 1 1 1 0 Hydrophobic surface binding protein A NiFeSe_Hases PF00374.19 EER23213.1 - 0.008 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Gpi1 PF05024.15 EER23214.1 - 1e-75 253.9 8.7 1.7e-75 253.2 8.7 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.21 EER23215.1 - 3e-81 272.0 0.1 6.1e-81 271.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EER23215.1 - 7.7e-38 130.6 0.5 2e-37 129.3 0.5 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EER23215.1 - 2.2e-19 70.1 0.2 1.1e-18 67.8 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EER23215.1 - 3e-18 66.0 1.1 8e-18 64.6 1.1 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 EER23215.1 - 1e-15 57.9 0.0 9.3e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 MutS domain I ArdA PF07275.11 EER23215.1 - 0.07 13.7 0.6 0.45 11.1 0.1 2.4 2 0 0 2 2 2 0 Antirestriction protein (ArdA) CDT1_C PF16679.5 EER23216.1 - 1.4e-19 70.3 0.1 4.4e-19 68.7 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Apolipoprotein PF01442.18 EER23217.1 - 0.00059 19.8 4.5 0.00078 19.4 4.5 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2884 PF11101.8 EER23217.1 - 0.029 13.9 0.7 0.035 13.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) GrpE PF01025.19 EER23217.1 - 0.034 13.8 1.1 0.041 13.5 1.1 1.2 1 0 0 1 1 1 0 GrpE Phasin PF05597.11 EER23217.1 - 0.077 13.0 4.3 0.14 12.2 4.2 1.5 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PhoU_div PF01865.16 EER23217.1 - 0.12 11.7 2.5 0.19 11.1 2.5 1.2 1 1 0 1 1 1 0 Protein of unknown function DUF47 YbjQ_1 PF01906.17 EER23217.1 - 0.51 11.0 1.8 21 5.8 0.1 2.2 1 1 1 2 2 2 0 Putative heavy-metal-binding Borrelia_P83 PF05262.11 EER23217.1 - 0.57 8.6 11.7 0.7 8.3 11.7 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF883 PF05957.13 EER23217.1 - 1.5 9.5 12.2 3.2 8.4 8.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 EER23217.1 - 8.8 6.4 12.9 2.4 8.3 1.4 2.2 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) YtxH PF12732.7 EER23217.1 - 9.5 6.8 15.8 1.3e+03 -0.0 15.8 2.8 1 1 0 1 1 1 0 YtxH-like protein Frag1 PF10277.9 EER23218.1 - 5.6e-42 143.7 4.0 5.6e-42 143.7 4.0 2.7 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 EER23218.1 - 0.0044 16.6 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2207 PF09972.9 EER23218.1 - 0.19 10.5 1.9 19 3.9 1.4 3.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3464 PF11947.8 EER23218.1 - 9.7 5.9 6.7 0.99 9.1 0.7 2.5 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 U3_assoc_6 PF08640.11 EER23219.1 - 2.6e-30 104.3 2.4 1.7e-28 98.5 1.1 2.4 2 0 0 2 2 2 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EER23219.1 - 1.8e-06 28.3 0.9 0.15 13.0 0.3 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 EER23219.1 - 0.007 15.5 0.1 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference RF-1 PF00472.20 EER23220.1 - 6.9e-22 77.6 0.8 1.1e-21 76.9 0.8 1.3 1 0 0 1 1 1 1 RF-1 domain CCDC14 PF15254.6 EER23220.1 - 0.0006 18.6 0.1 0.00081 18.2 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 RRM_1 PF00076.22 EER23221.1 - 1.4e-10 40.8 0.0 2.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER23221.1 - 1.4e-05 24.7 0.0 3.9e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.17 EER23222.1 - 6.5e-24 84.0 2.4 7.9e-24 83.7 2.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EER23222.1 - 0.029 14.7 1.4 0.065 13.5 1.4 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 SYS1 PF09801.9 EER23223.1 - 2.9e-53 179.9 7.7 3.4e-53 179.7 7.7 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF485 PF04341.12 EER23223.1 - 1.1 9.3 8.2 0.36 10.8 4.8 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF485 COG5 PF10392.9 EER23224.1 - 1.8e-41 141.4 0.5 1.7e-40 138.3 0.0 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 zf-C2H2 PF00096.26 EER23225.1 - 8e-06 26.0 12.2 0.0033 17.8 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER23225.1 - 0.0003 21.1 3.8 0.0003 21.1 3.8 2.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER23225.1 - 0.00078 20.1 11.6 0.079 13.8 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 EER23225.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 EER23225.1 - 1.7 8.5 5.6 2.6 7.9 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Lactamase_B_6 PF16661.5 EER23228.1 - 2.3e-66 222.9 0.0 4.7e-66 221.9 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EER23228.1 - 8e-46 156.3 1.9 1.1e-45 155.8 0.0 2.1 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EER23228.1 - 2e-17 63.5 0.0 6.3e-17 61.9 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 EER23228.1 - 7.7e-12 45.0 0.0 1.6e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EER23228.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily AA_permease_2 PF13520.6 EER23230.1 - 4.2e-57 193.9 45.3 5.1e-57 193.6 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER23230.1 - 7.3e-18 64.4 38.3 9.7e-18 64.0 38.3 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.11 EER23230.1 - 0.99 8.5 5.9 0.5 9.5 1.1 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 DUF2721 PF11026.8 EER23230.1 - 1.2 9.0 0.0 1.2 9.0 0.0 4.6 5 1 0 5 5 5 0 Protein of unknown function (DUF2721) Sec23_trunk PF04811.15 EER23231.1 - 6.8e-53 179.7 0.0 1.8e-52 178.3 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EER23231.1 - 4.3e-26 90.7 0.0 9.4e-26 89.6 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EER23231.1 - 7.4e-17 61.9 0.0 2e-16 60.5 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EER23231.1 - 3.5e-16 59.0 4.5 8.2e-16 57.8 4.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EER23231.1 - 3.7e-07 29.9 0.0 9.1e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Fe-ADH PF00465.19 EER23231.1 - 0.05 12.4 0.1 0.1 11.4 0.1 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Bys1 PF04681.12 EER23232.1 - 3.8e-05 23.7 0.5 8e-05 22.6 0.5 1.5 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein ABC_tran PF00005.27 EER23233.1 - 5.9e-51 172.6 0.2 7.8e-25 88.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC2_membrane PF01061.24 EER23233.1 - 3.4e-48 163.9 33.8 3.6e-26 91.9 14.8 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 EER23233.1 - 5.4e-11 42.9 4.2 0.0058 16.5 0.0 4.5 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EER23233.1 - 5.5e-08 33.6 0.0 0.0018 18.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EER23233.1 - 7e-08 33.0 0.2 0.01 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EER23233.1 - 8.4e-08 32.3 0.3 0.0041 17.0 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EER23233.1 - 2.5e-06 27.2 0.1 0.053 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EER23233.1 - 4e-06 26.5 1.9 0.09 12.5 0.6 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EER23233.1 - 5.1e-06 26.1 0.8 0.093 12.2 0.1 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EER23233.1 - 2.5e-05 24.2 1.0 0.05 13.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EER23233.1 - 3e-05 24.3 0.1 0.41 10.9 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EER23233.1 - 3.9e-05 23.4 0.0 0.077 12.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EER23233.1 - 0.00021 21.7 0.1 0.91 9.9 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EER23233.1 - 0.00032 21.0 0.9 0.21 11.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EER23233.1 - 0.0011 18.1 0.0 0.48 9.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.6 EER23233.1 - 0.0011 19.5 0.2 0.91 10.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EER23233.1 - 0.0031 17.9 0.1 1.4 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase cobW PF02492.19 EER23233.1 - 0.0033 17.0 2.3 0.3 10.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EER23233.1 - 0.0046 16.7 0.2 5 6.7 0.5 3.1 3 0 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 EER23233.1 - 0.0048 16.8 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_5 PF07728.14 EER23233.1 - 0.0056 16.7 0.0 4.3 7.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EER23233.1 - 0.0076 16.6 0.2 1.4 9.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EER23233.1 - 0.029 14.2 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EER23233.1 - 0.03 14.5 0.1 2.4 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 EER23233.1 - 0.03 13.8 1.5 3.3 7.1 0.4 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Roc PF08477.13 EER23233.1 - 0.034 14.4 0.3 6.1 7.1 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EER23233.1 - 0.034 13.9 0.0 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EER23233.1 - 0.052 12.9 0.1 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATP-synt_ab PF00006.25 EER23233.1 - 0.085 12.5 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EER23233.1 - 0.093 12.1 0.1 0.89 8.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 EER23233.1 - 0.11 12.5 0.0 33 4.5 0.1 3.1 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 EER23233.1 - 0.13 12.2 1.1 7.5 6.5 0.2 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.17 EER23233.1 - 0.15 11.8 0.3 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EER23233.1 - 0.17 11.1 0.4 3.7 6.8 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin MMR_HSR1 PF01926.23 EER23233.1 - 0.19 11.8 3.4 1.3 9.1 0.9 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fungal_trans_2 PF11951.8 EER23234.1 - 3.2e-68 230.3 0.1 4.1e-68 229.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER23234.1 - 1.4e-09 37.9 10.5 2.4e-09 37.2 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.19 EER23234.1 - 0.45 10.5 6.8 1.3 9.2 6.8 1.8 1 0 0 1 1 1 0 AT hook motif DUF2434 PF10361.9 EER23236.1 - 6e-131 435.8 5.7 7.5e-131 435.5 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) 7tm_7 PF08395.12 EER23236.1 - 6.3 5.9 13.6 0.74 9.0 1.2 2.6 1 1 1 2 2 2 0 7tm Chemosensory receptor Gti1_Pac2 PF09729.9 EER23237.1 - 1e-44 152.8 5.6 1.2e-38 133.0 0.1 2.4 2 1 1 3 3 3 2 Gti1/Pac2 family Peptidase_M6 PF05547.11 EER23238.1 - 1.3e-06 27.1 1.2 0.00026 19.5 1.2 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 FAD_binding_4 PF01565.23 EER23239.1 - 1.2e-16 60.7 0.0 1.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain tRNA-synt_2 PF00152.20 EER23240.1 - 3.1e-72 243.3 0.0 1e-71 241.6 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EER23240.1 - 5.4e-07 29.5 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain CtsR_C PF17727.1 EER23240.1 - 0.034 14.3 0.0 0.086 13.0 0.0 1.6 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain RRM_1 PF00076.22 EER23241.1 - 4.3e-10 39.3 0.0 9.9e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2884 PF11101.8 EER23241.1 - 0.033 13.7 0.3 0.064 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) SesA PF17107.5 EER23241.1 - 0.054 13.7 0.6 0.65 10.2 0.4 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Baculo_PEP_C PF04513.12 EER23241.1 - 0.16 12.0 2.5 0.12 12.5 0.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 EER23241.1 - 0.29 11.2 2.2 0.57 10.2 0.3 2.4 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) ApoLp-III PF07464.11 EER23241.1 - 0.76 9.9 6.1 2.3 8.3 6.1 1.9 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF4337 PF14235.6 EER23241.1 - 2.2 8.4 7.6 1 9.4 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) MOZ_SAS PF01853.18 EER23242.1 - 2.3e-64 216.4 0.0 3e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EER23242.1 - 1.9e-16 59.4 0.6 3.9e-16 58.4 0.6 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain I_LWEQ PF01608.17 EER23242.1 - 0.076 13.3 2.0 0.11 12.7 2.0 1.2 1 0 0 1 1 1 0 I/LWEQ domain IF2_N PF04760.15 EER23242.1 - 0.13 12.1 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Cpn60_TCP1 PF00118.24 EER23243.1 - 3.9e-164 546.9 0.3 4.4e-164 546.7 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 EER23243.1 - 0.057 11.9 0.0 0.083 11.4 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Nop PF01798.18 EER23244.1 - 1.5e-88 296.1 0.0 1.5e-88 296.1 0.0 2.0 2 0 0 2 2 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EER23244.1 - 5.3e-19 68.4 0.0 5.3e-19 68.4 0.0 2.5 2 1 0 2 2 1 1 NOP5NT (NUC127) domain Rrn6 PF10214.9 EER23244.1 - 0.0019 16.8 1.0 0.0021 16.7 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor DUF1682 PF07946.14 EER23244.1 - 0.83 8.8 25.0 12 5.0 25.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) CobT PF06213.12 EER23244.1 - 0.84 9.0 24.8 0.36 10.2 21.7 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RP-C_C PF11800.8 EER23244.1 - 0.96 9.5 11.4 16 5.5 0.0 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region GAGA_bind PF06217.12 EER23244.1 - 1.7 8.9 18.1 4.1 7.6 18.1 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.17 EER23244.1 - 3.2 7.9 9.4 6.1 6.9 9.4 1.4 1 0 0 1 1 1 0 DDHD domain DUF4746 PF15928.5 EER23244.1 - 4.4 6.7 20.3 6.7 6.0 20.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1943 PF09172.11 EER23244.1 - 7.4 5.7 12.0 17 4.5 12.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) RR_TM4-6 PF06459.12 EER23244.1 - 7.7 6.3 27.8 6.4 6.5 26.3 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EER23244.1 - 8.6 6.8 19.9 18 5.7 19.9 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3767 PF12597.8 EER23246.1 - 2.5e-35 120.3 0.7 3.4e-35 119.9 0.1 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.12 EER23246.1 - 0.1 12.1 0.5 0.14 11.7 0.5 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT MRPL52 PF18699.1 EER23246.1 - 7 6.9 10.9 11 6.3 10.9 1.3 1 0 0 1 1 1 0 Mitoribosomal protein mL52 DUF1744 PF08490.12 EER23247.1 - 5.8e-155 515.8 0.2 8.7e-155 515.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EER23247.1 - 7.1e-81 272.0 1.9 7.1e-81 272.0 1.9 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EER23247.1 - 2.4e-15 56.2 0.0 3e-12 46.0 0.0 3.6 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EER23247.1 - 1e-08 35.1 0.4 3.6e-08 33.3 0.4 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EER23247.1 - 1.9e-05 24.7 0.1 0.00016 21.7 0.1 2.7 3 0 0 3 3 3 1 RNase_H superfamily Pkinase PF00069.25 EER23248.1 - 2.7e-73 246.6 0.0 3.7e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23248.1 - 1.4e-29 103.1 0.0 2e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER23248.1 - 7.1e-08 32.1 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EER23248.1 - 0.00012 21.0 0.0 0.00023 20.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EER23248.1 - 0.00051 20.1 0.1 0.00086 19.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EER23248.1 - 0.00061 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AMMECR1 PF01871.17 EER23249.1 - 3.6e-39 134.1 0.0 7.4e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 SGT1 PF07093.11 EER23250.1 - 9.7e-91 305.0 27.6 2.7e-81 273.8 0.0 3.0 1 1 2 3 3 3 3 SGT1 protein Cnn_1N PF07989.11 EER23251.1 - 1.6e-24 85.9 4.6 1.6e-24 85.9 4.6 13.8 4 3 10 15 15 15 1 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 EER23251.1 - 3.1e-20 72.5 1.8 3.1e-20 72.5 1.8 4.0 4 1 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fez1 PF06818.15 EER23251.1 - 0.00028 21.4 158.2 0.13 12.7 15.4 8.9 1 1 5 7 7 7 5 Fez1 TMF_DNA_bd PF12329.8 EER23251.1 - 0.0035 17.3 17.6 0.0035 17.3 17.6 15.8 8 5 7 16 16 16 2 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 EER23251.1 - 0.0042 17.2 14.0 0.0042 17.2 14.0 11.6 3 2 6 10 10 10 2 TPR/MLP1/MLP2-like protein PspB PF06667.12 EER23251.1 - 0.035 14.1 0.6 0.035 14.1 0.6 7.7 9 2 0 9 9 9 0 Phage shock protein B Spc110_C PF18520.1 EER23251.1 - 0.95 9.1 10.0 0.029 14.0 1.5 3.1 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain AAA PF00004.29 EER23252.1 - 5.1e-42 143.4 0.0 9.4e-42 142.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EER23252.1 - 2.8e-30 104.1 0.1 1e-29 102.3 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EER23252.1 - 3.9e-23 81.3 2.3 3.9e-23 81.3 2.3 2.0 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EER23252.1 - 2.6e-07 30.3 0.2 4.2e-06 26.5 0.0 2.7 3 0 0 3 3 3 1 AAA+ lid domain RuvB_N PF05496.12 EER23252.1 - 2.6e-06 27.3 0.0 5.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EER23252.1 - 1.2e-05 25.8 0.0 0.00011 22.6 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EER23252.1 - 3.6e-05 23.8 0.0 0.00012 22.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EER23252.1 - 5.6e-05 23.5 0.0 0.011 16.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 EER23252.1 - 6.3e-05 22.8 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EER23252.1 - 0.00013 22.3 0.1 0.019 15.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EER23252.1 - 0.00013 22.1 0.0 0.0031 17.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EER23252.1 - 0.00018 20.8 0.0 0.0007 18.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EER23252.1 - 0.00021 21.4 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EER23252.1 - 0.00025 20.4 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EER23252.1 - 0.00044 20.8 0.0 0.0018 18.8 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EER23252.1 - 0.0016 18.6 0.0 0.0046 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EER23252.1 - 0.0034 17.1 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EER23252.1 - 0.01 16.2 0.0 0.036 14.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EER23252.1 - 0.012 15.2 0.1 0.56 9.7 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 EER23252.1 - 0.013 15.1 0.1 0.087 12.3 0.0 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EER23252.1 - 0.022 14.2 0.0 0.082 12.3 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EER23252.1 - 0.055 13.4 0.0 0.69 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 EER23252.1 - 0.074 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EER23252.1 - 0.077 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 EER23252.1 - 0.081 12.3 0.1 5.1 6.4 0.0 2.6 2 1 1 3 3 3 0 KaiC Torsin PF06309.11 EER23252.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 EER23252.1 - 0.11 12.4 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 EER23252.1 - 0.16 11.8 0.0 0.51 10.2 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EER23252.1 - 0.16 11.6 0.1 0.51 10.0 0.0 1.8 2 0 0 2 2 1 0 Cytidylate kinase Sigma54_activat PF00158.26 EER23252.1 - 0.18 11.5 0.0 0.52 10.0 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain USP8_dimer PF08969.11 EER23252.1 - 0.26 11.5 3.4 0.14 12.3 1.2 1.8 2 0 0 2 2 1 0 USP8 dimerisation domain TPR_1 PF00515.28 EER23252.1 - 0.74 9.7 4.5 0.2 11.5 0.6 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 EER23253.1 - 2.5e-22 78.8 14.8 3.5e-22 78.4 14.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EER23253.1 - 1.1e-05 25.5 4.9 1.4e-05 25.0 4.9 1.2 1 0 0 1 1 1 1 Prefoldin subunit APG6_N PF17675.1 EER23253.1 - 0.0056 17.2 16.1 0.11 13.0 1.9 2.2 2 0 0 2 2 2 2 Apg6 coiled-coil region FTA4 PF13093.6 EER23253.1 - 0.0096 15.8 1.9 0.014 15.3 1.9 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spc24 PF08286.11 EER23253.1 - 0.0098 16.1 14.7 0.053 13.8 4.3 2.1 1 1 0 2 2 2 2 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 EER23253.1 - 0.012 16.0 11.2 0.35 11.4 1.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SOGA PF11365.8 EER23253.1 - 0.02 16.0 5.1 0.18 12.9 0.3 2.1 2 0 0 2 2 2 0 Protein SOGA Rx_N PF18052.1 EER23253.1 - 0.031 14.6 9.6 0.31 11.4 0.5 2.1 2 0 0 2 2 2 0 Rx N-terminal domain Prefoldin PF02996.17 EER23253.1 - 0.035 14.0 2.1 0.035 14.0 2.1 2.5 2 1 0 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.8 EER23253.1 - 0.036 14.3 12.3 0.21 11.8 3.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding PHM7_cyt PF14703.6 EER23253.1 - 0.041 14.1 8.1 0.06 13.6 8.1 1.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter CENP-F_leu_zip PF10473.9 EER23253.1 - 0.045 13.8 13.9 0.56 10.2 3.9 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 EER23253.1 - 0.062 13.9 10.1 1.3 9.6 2.0 2.1 2 0 0 2 2 2 0 Initiation control protein YabA CENP-Q PF13094.6 EER23253.1 - 0.09 13.0 8.1 0.87 9.8 2.6 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit XhlA PF10779.9 EER23253.1 - 0.1 12.8 1.1 0.1 12.8 1.1 2.1 2 0 0 2 2 2 0 Haemolysin XhlA ATG16 PF08614.11 EER23253.1 - 0.13 12.4 14.5 0.053 13.8 5.2 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DHR10 PF18595.1 EER23253.1 - 0.13 12.3 16.4 0.23 11.5 6.2 2.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain COG2 PF06148.11 EER23253.1 - 0.19 11.8 6.7 1.2 9.2 0.6 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Bcr-Abl_Oligo PF09036.10 EER23253.1 - 0.21 11.6 3.4 0.88 9.6 0.3 2.1 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Spc7 PF08317.11 EER23253.1 - 0.24 10.3 14.3 0.3 9.9 14.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 EER23253.1 - 0.26 11.7 14.2 0.39 11.1 5.4 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Siah-Interact_N PF09032.11 EER23253.1 - 0.44 10.9 12.8 1.8 8.9 2.5 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal ABC_tran_CTD PF16326.5 EER23253.1 - 0.6 10.4 16.9 0.28 11.4 2.3 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain GrpE PF01025.19 EER23253.1 - 0.62 9.7 13.8 0.78 9.4 2.6 2.2 2 0 0 2 2 2 0 GrpE TPR_MLP1_2 PF07926.12 EER23253.1 - 0.99 9.5 19.5 0.67 10.0 5.7 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 EER23253.1 - 1.3 8.9 20.6 0.46 10.3 2.8 3.1 2 1 1 3 3 3 0 Septum formation initiator FliD_C PF07195.12 EER23253.1 - 1.4 8.3 8.6 1.5 8.2 7.0 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FlaC_arch PF05377.11 EER23253.1 - 1.4 9.4 10.4 2.2 8.8 1.7 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ERM PF00769.19 EER23253.1 - 1.7 8.4 18.2 11 5.8 18.2 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 EER23253.1 - 1.8 7.8 10.9 3.1 7.1 10.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FlxA PF14282.6 EER23253.1 - 1.9 8.6 21.5 0.49 10.4 5.5 2.3 2 0 0 2 2 2 0 FlxA-like protein ZapB PF06005.12 EER23253.1 - 1.9 9.0 14.1 1.2 9.6 6.8 2.2 2 0 0 2 2 2 0 Cell division protein ZapB Cluap1 PF10234.9 EER23253.1 - 3.1 7.1 13.6 0.094 12.1 2.7 2.2 2 1 0 2 2 2 0 Clusterin-associated protein-1 Csm1_N PF18504.1 EER23253.1 - 3.2 8.2 15.0 2.1 8.8 1.4 3.1 2 2 1 3 3 3 0 Csm1 N-terminal domain Osmo_CC PF08946.10 EER23253.1 - 4.7 7.5 10.6 0.085 13.1 2.0 2.3 2 1 0 2 2 2 0 Osmosensory transporter coiled coil TolA_bind_tri PF16331.5 EER23253.1 - 4.9 7.3 14.8 0.59 10.2 0.3 2.6 2 1 0 2 2 2 0 TolA binding protein trimerisation Allexi_40kDa PF05549.11 EER23253.1 - 5.3 6.5 5.9 12 5.3 0.9 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Fmp27_WPPW PF10359.9 EER23253.1 - 7.3 5.3 11.8 1 8.1 2.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF4140 PF13600.6 EER23253.1 - 9.8 6.7 12.1 23 5.5 0.7 2.6 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) iPGM_N PF06415.13 EER23254.1 - 5.2e-77 258.1 0.0 7.6e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EER23254.1 - 2.7e-71 239.9 0.0 3.1e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EER23254.1 - 4.2e-07 29.9 0.0 6.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EER23254.1 - 6.5e-06 25.8 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Methyltransf_31 PF13847.6 EER23254.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PglZ PF08665.12 EER23254.1 - 0.11 12.5 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 PglZ domain Alk_phosphatase PF00245.20 EER23254.1 - 0.15 11.0 0.0 0.54 9.1 0.0 1.8 2 0 0 2 2 2 0 Alkaline phosphatase Med9 PF07544.13 EER23255.1 - 1.7e-16 60.0 0.2 2.7e-16 59.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.12 EER23255.1 - 0.0078 16.8 0.5 0.019 15.6 0.5 1.6 1 0 0 1 1 1 1 SlyX Fib_alpha PF08702.10 EER23255.1 - 0.093 12.9 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Phage_GP20 PF06810.11 EER23255.1 - 0.1 12.4 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Sec20 PF03908.13 EER23255.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Sec20 TRAF_BIRC3_bd PF16673.5 EER23255.1 - 0.17 11.7 2.4 0.26 11.1 2.4 1.2 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain XhlA PF10779.9 EER23255.1 - 0.31 11.3 1.3 0.49 10.6 1.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Med21 PF11221.8 EER23255.1 - 1.8 8.8 18.1 31 4.8 18.1 2.2 1 1 0 1 1 1 0 Subunit 21 of Mediator complex SHMT PF00464.19 EER23256.1 - 2.2e-210 698.3 0.0 2.6e-210 698.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Cys_Met_Meta_PP PF01053.20 EER23256.1 - 0.09 11.3 0.0 0.19 10.2 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EER23256.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase RNA_polI_A34 PF08208.11 EER23257.1 - 5.8e-34 118.0 28.1 5.8e-34 118.0 28.1 3.3 2 2 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 CLP1_P PF16575.5 EER23258.1 - 9e-28 97.3 0.0 2e-27 96.2 0.0 1.6 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EER23258.1 - 0.0023 18.1 2.3 0.06 13.5 0.1 3.0 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.22 EER23258.1 - 0.01 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EER23258.1 - 0.14 12.7 0.0 0.36 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EER23258.1 - 0.18 11.1 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_22 PF13401.6 EER23258.1 - 0.19 12.0 0.0 0.64 10.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Folliculin PF11704.8 EER23259.1 - 4.6e-50 170.1 0.0 6.5e-50 169.6 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport CSN8_PSD8_EIF3K PF10075.9 EER23260.1 - 7.3e-50 168.7 0.0 1.2e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family PDCD2_C PF04194.13 EER23261.1 - 4.7e-43 147.3 0.3 1.9e-41 142.0 0.0 2.9 2 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Kdo PF06293.14 EER23262.1 - 5.9e-07 29.0 0.1 1.2e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER23262.1 - 8.3e-05 22.6 0.1 0.0009 19.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 EER23262.1 - 0.0051 16.2 0.0 0.0051 16.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Choline_kinase PF01633.20 EER23262.1 - 0.047 13.3 1.3 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EER23262.1 - 0.058 13.0 0.5 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 RIO1 family FERM_M PF00373.18 EER23262.1 - 0.93 9.9 2.9 3.2 8.2 2.6 1.9 2 0 0 2 2 2 0 FERM central domain Acyl-CoA_ox_N PF14749.6 EER23263.1 - 2.6e-22 79.7 0.8 4.5e-22 78.9 0.8 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.19 EER23263.1 - 1.7e-13 50.5 0.0 3.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EER23263.1 - 7.8e-11 42.0 0.0 1.8e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EER23263.1 - 0.055 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 EER23264.1 - 2e-44 151.3 0.0 4.3e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EER23264.1 - 9.7e-26 90.8 0.0 4.6e-25 88.6 0.0 2.1 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EER23264.1 - 2.3e-06 27.7 0.0 6.2e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF2398 PF09661.10 EER23264.1 - 0.023 14.0 0.1 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2398) Acyl-CoA_dh_N PF02771.16 EER23264.1 - 0.047 14.4 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Receptor_2B4 PF11465.8 EER23265.1 - 0.15 12.3 0.3 0.24 11.6 0.3 1.3 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Alanine_zipper PF11839.8 EER23265.1 - 0.23 11.9 5.9 0.65 10.4 5.9 1.7 1 0 0 1 1 1 0 Alanine-zipper, major outer membrane lipoprotein Prenylcys_lyase PF07156.14 EER23267.1 - 8.8e-97 324.4 0.0 1.1e-96 324.1 0.0 1.0 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 EER23267.1 - 1.2e-14 54.5 0.0 4e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EER23267.1 - 1.9e-12 47.2 0.0 4.8e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER23267.1 - 8.9e-05 22.2 0.1 0.00043 20.0 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EER23267.1 - 0.00044 20.3 0.1 0.0057 16.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EER23267.1 - 0.0052 16.0 0.0 0.02 14.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER23267.1 - 0.056 12.6 1.6 1.9 7.5 0.0 2.6 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EER23267.1 - 0.092 12.0 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 EER23268.1 - 1.8e-07 31.3 0.0 3.1e-06 27.3 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EER23268.1 - 0.00011 22.2 0.0 0.0064 16.5 0.0 2.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EER23268.1 - 0.00066 19.0 0.0 0.039 13.2 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF2407_C PF13373.6 EER23268.1 - 0.0011 19.2 0.0 0.0054 16.9 0.0 2.0 2 0 0 2 2 2 1 DUF2407 C-terminal domain Shikimate_DH PF01488.20 EER23268.1 - 0.002 18.2 0.0 0.21 11.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.19 EER23268.1 - 0.0025 16.3 0.0 0.015 13.7 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.19 EER23268.1 - 0.0031 16.9 0.0 0.022 14.1 0.0 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EER23268.1 - 0.082 13.5 0.1 30 5.3 0.6 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 EER23268.1 - 0.083 13.5 0.3 14 6.3 0.2 2.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GCSF PF16647.5 EER23268.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Granulocyte colony-stimulating factor Pyr_redox_3 PF13738.6 EER23268.1 - 0.14 11.3 2.0 7 5.8 0.1 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amidase PF01425.21 EER23269.1 - 2.3e-85 287.3 0.0 4.5e-85 286.3 0.0 1.4 1 1 0 1 1 1 1 Amidase Glyco_transf_28 PF03033.20 EER23270.1 - 2.4e-29 102.2 0.0 5.9e-29 100.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EER23270.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prefoldin PF02996.17 EER23271.1 - 1e-27 96.4 0.2 1.5e-27 95.9 0.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Syntaxin-6_N PF09177.11 EER23271.1 - 0.069 13.7 0.5 10 6.7 0.0 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Methyltransf_25 PF13649.6 EER23272.1 - 1.4e-10 41.7 0.1 2.5e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER23272.1 - 8.4e-07 28.6 0.3 1.3e-06 27.9 0.1 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EER23272.1 - 9.3e-07 29.4 0.1 1.8e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER23272.1 - 1.8e-06 28.6 0.0 3.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EER23272.1 - 6e-06 25.8 0.0 9.6e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.6 EER23272.1 - 2.8e-05 24.0 0.0 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER23272.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER23272.1 - 0.0039 16.7 0.1 0.006 16.1 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EER23272.1 - 0.075 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_4 PF13577.6 EER23273.1 - 0.011 15.8 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.7 EER23273.1 - 0.058 14.1 0.0 0.089 13.4 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain AMP-binding PF00501.28 EER23274.1 - 1.3e-142 475.4 0.0 2.4e-70 237.3 0.1 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EER23274.1 - 1.8e-87 294.0 0.0 2.7e-46 158.2 0.0 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EER23274.1 - 5.7e-23 81.1 0.1 9.1e-14 51.6 0.1 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EER23274.1 - 6.1e-08 33.5 0.0 0.0054 17.7 0.0 3.7 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Beta-lactamase PF00144.24 EER23275.1 - 3.3e-53 181.1 0.0 4.4e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EER23275.1 - 4.3e-06 27.1 0.0 1e-05 25.9 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) Vma12 PF11712.8 EER23276.1 - 3.4e-39 134.1 0.0 4.9e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase TNFR_16_TM PF18422.1 EER23276.1 - 0.14 12.1 0.8 0.32 11.0 0.8 1.6 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Amidohydro_1 PF01979.20 EER23277.1 - 4.6e-28 98.5 0.0 1.3e-26 93.8 0.0 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EER23277.1 - 2.3e-14 53.7 0.0 1.3e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 EER23277.1 - 0.0092 15.8 0.0 0.019 14.8 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Glyco_transf_24 PF18404.1 EER23278.1 - 2.7e-149 495.9 1.9 3.8e-149 495.4 1.9 1.2 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EER23278.1 - 7.4e-67 226.0 0.0 4.8e-66 223.3 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EER23278.1 - 9.8e-51 172.3 0.3 3.2e-50 170.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EER23278.1 - 9e-42 142.2 0.1 5.7e-41 139.6 0.2 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EER23278.1 - 4.9e-41 139.3 0.0 9.2e-41 138.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 EER23278.1 - 1.8e-39 135.9 0.0 4.5e-39 134.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EER23278.1 - 7.1e-05 22.5 0.1 0.00037 20.1 0.0 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 8 PhzC-PhzF PF02567.16 EER23280.1 - 1.6e-18 67.2 0.6 6.6e-09 35.6 0.2 2.3 2 1 0 2 2 2 2 Phenazine biosynthesis-like protein HSP70 PF00012.20 EER23281.1 - 1.9e-87 293.9 3.1 1.5e-86 290.9 0.3 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EER23281.1 - 6.2e-12 45.0 0.3 1.1e-11 44.2 0.3 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 EER23281.1 - 1.8e-05 24.0 0.2 0.039 13.0 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; Peripla_BP_6 PF13458.6 EER23281.1 - 0.0039 16.9 0.4 0.009 15.7 0.3 1.7 1 1 0 1 1 1 1 Periplasmic binding protein Rpp20 PF12328.8 EER23282.1 - 5.9e-51 172.0 5.0 8.7e-51 171.5 5.0 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EER23282.1 - 1.7e-17 63.0 1.1 3.4e-17 62.0 1.1 1.6 1 0 0 1 1 1 1 Alba DUF4168 PF13767.6 EER23282.1 - 1.6 10.0 5.0 15 6.8 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) KH_6 PF15985.5 EER23284.1 - 8.4e-18 64.5 1.2 1.9e-17 63.4 1.2 1.6 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EER23284.1 - 0.0059 16.5 1.2 0.034 14.1 0.2 2.6 3 0 0 3 3 3 1 Exosome complex exonuclease Rrp40 N-terminal domain Zip PF02535.22 EER23285.1 - 4.9e-50 170.6 2.0 6.8e-50 170.2 2.0 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Rogdi_lz PF10259.9 EER23287.1 - 4.9e-83 278.7 0.0 5.6e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.10 EER23288.1 - 1.5e-28 99.9 0.0 1.1e-27 97.0 0.0 2.4 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EER23288.1 - 0.00063 19.6 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER23288.1 - 0.0095 16.7 0.0 0.032 15.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23288.1 - 0.027 15.2 0.0 0.12 13.1 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EER23288.1 - 0.066 13.9 0.0 0.19 12.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DASH_Spc19 PF08287.11 EER23289.1 - 2.8e-51 173.5 3.4 3.7e-51 173.1 3.4 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 EER23289.1 - 0.017 15.1 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Mur ligase middle domain COG5 PF10392.9 EER23289.1 - 0.51 10.5 5.9 7.2 6.8 0.4 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 IFP_35_N PF07334.13 EER23289.1 - 1.2 9.3 5.3 8.1 6.6 2.5 2.9 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ATP-synt_J PF04911.12 EER23290.1 - 1.5e-25 88.5 0.8 1.7e-25 88.3 0.8 1.1 1 0 0 1 1 1 1 ATP synthase j chain Ribosomal_S14 PF00253.21 EER23291.1 - 9.8e-23 79.7 1.6 1.5e-21 75.8 0.2 2.3 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e LRR_8 PF13855.6 EER23293.1 - 1.6e-11 43.8 6.4 3.7e-09 36.2 3.4 2.7 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EER23293.1 - 0.005 17.2 2.2 0.005 17.2 2.2 4.0 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) Mucin PF01456.17 EER23294.1 - 0.091 12.7 25.7 0.12 12.4 25.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein FHA PF00498.26 EER23296.1 - 5.9e-17 61.8 0.0 1.5e-16 60.5 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EER23296.1 - 0.00011 22.4 0.1 0.00054 20.2 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FlaC_arch PF05377.11 EER23296.1 - 3 8.3 6.1 33 5.0 0.5 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CdvA PF18822.1 EER23296.1 - 4.1 7.2 12.9 12 5.7 4.7 2.8 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Y_phosphatase3 PF13350.6 EER23297.1 - 2e-55 188.3 0.0 2.6e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EER23297.1 - 0.0063 16.1 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EER23297.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 EER23297.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 EER23297.1 - 0.17 10.8 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Amino_oxidase PF01593.24 EER23298.1 - 7.3e-31 107.9 0.1 2.1e-30 106.4 0.1 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EER23298.1 - 1.3e-05 25.3 0.0 3.9e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lipase_chap PF03280.14 EER23298.1 - 0.045 13.7 0.3 0.08 12.9 0.3 1.3 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein FAD_binding_3 PF01494.19 EER23299.1 - 1.1e-10 41.3 1.2 2.1e-09 37.1 1.2 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EER23299.1 - 9.4e-05 22.2 1.3 0.00028 20.6 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER23299.1 - 0.00015 21.9 0.1 0.00046 20.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EER23299.1 - 0.00039 19.4 1.1 0.00069 18.6 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 EER23299.1 - 0.0012 18.2 0.2 0.0076 15.5 0.0 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EER23299.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain EI24 PF07264.11 EER23300.1 - 8.4e-12 45.7 7.7 1.1e-11 45.3 7.7 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-RING_2 PF13639.6 EER23301.1 - 4.2e-12 46.2 5.4 6.6e-12 45.6 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EER23301.1 - 7.7e-09 35.7 2.3 1.5e-08 34.8 2.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EER23301.1 - 1.5e-08 34.3 4.6 2.4e-08 33.7 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 EER23301.1 - 1.6e-08 34.4 0.0 3.7e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 EER23301.1 - 5.1e-08 32.6 3.9 8.1e-08 32.0 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EER23301.1 - 2.7e-07 30.2 3.2 2.7e-07 30.2 3.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EER23301.1 - 1.1e-06 28.5 2.5 1.7e-06 27.9 2.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EER23301.1 - 1.7e-05 24.5 2.8 2.6e-05 24.0 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER23301.1 - 8.2e-05 22.6 3.0 9.5e-05 22.3 0.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EER23301.1 - 0.0012 18.8 0.7 0.0024 17.9 0.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EER23301.1 - 0.017 15.3 4.6 0.033 14.4 4.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EER23301.1 - 0.017 14.9 3.3 0.03 14.2 3.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EER23301.1 - 0.21 11.2 2.7 0.39 10.4 2.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EER23301.1 - 0.32 11.2 2.6 0.74 10.0 2.6 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EER23301.1 - 0.55 10.6 2.8 1 9.7 2.8 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EER23301.1 - 0.77 9.9 3.6 1.5 9.0 3.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EER23301.1 - 1 9.2 2.7 1.8 8.4 2.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain OTT_1508_deam PF14441.6 EER23303.1 - 1.2e-18 66.9 1.7 2.6e-18 65.8 1.7 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Raptor_N PF14538.6 EER23305.1 - 4.1e-65 218.2 0.0 2.7e-64 215.6 0.0 2.2 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EER23305.1 - 2.3e-05 25.1 7.0 0.53 11.2 0.0 6.2 5 1 0 5 5 5 2 WD domain, G-beta repeat HEAT PF02985.22 EER23305.1 - 0.00011 22.1 0.4 0.61 10.5 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat Atx10homo_assoc PF09759.9 EER23305.1 - 0.0038 17.2 0.2 0.0091 16.0 0.2 1.6 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain BBS2_Mid PF14783.6 EER23305.1 - 0.083 12.9 2.3 1.7 8.7 0.1 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Kelch_5 PF13854.6 EER23306.1 - 1.7e-32 110.8 3.5 2.3e-08 33.8 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EER23306.1 - 3.5e-31 107.0 12.6 4.2e-09 36.3 0.9 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EER23306.1 - 1.4e-28 98.2 4.1 1.2e-09 38.1 0.5 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EER23306.1 - 2.4e-28 97.4 1.5 3.8e-12 45.6 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EER23306.1 - 2.8e-28 97.6 15.2 1.3e-06 28.5 0.2 6.2 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EER23306.1 - 4.4e-20 70.8 5.9 1.5e-07 31.1 0.2 6.6 6 0 0 6 6 6 5 Kelch motif DUF4396 PF14342.6 EER23307.1 - 1.3e-42 145.5 5.5 1.8e-42 145.0 5.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) DUF5389 PF17364.2 EER23307.1 - 0.025 14.6 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5389) Pkinase PF00069.25 EER23308.1 - 4.8e-26 91.7 0.0 6e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23308.1 - 6.2e-14 51.9 0.0 8.1e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER23308.1 - 4.6e-09 35.5 0.0 6.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EER23308.1 - 0.00021 21.3 0.0 0.0015 18.5 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family bZIP_1 PF00170.21 EER23309.1 - 9.1e-07 28.9 12.9 1.8e-06 27.9 12.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor SHE3 PF17078.5 EER23309.1 - 6.1e-05 22.8 6.6 0.0001 22.1 6.6 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_2 PF07716.15 EER23309.1 - 0.0098 15.9 16.6 0.014 15.4 15.4 1.9 1 1 1 2 2 2 1 Basic region leucine zipper TMF_TATA_bd PF12325.8 EER23309.1 - 0.016 15.5 5.3 0.016 15.5 5.3 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 EER23309.1 - 0.038 11.9 0.9 0.048 11.6 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family U1snRNP70_N PF12220.8 EER23309.1 - 0.058 14.0 2.5 0.13 12.9 2.5 1.6 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Pox_A_type_inc PF04508.12 EER23309.1 - 0.072 13.0 2.3 0.17 11.8 2.3 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat bZIP_Maf PF03131.17 EER23309.1 - 0.073 13.6 13.1 0.15 12.6 13.1 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor GvpL_GvpF PF06386.11 EER23309.1 - 0.16 11.9 7.0 0.26 11.2 7.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF TMCO5 PF14992.6 EER23309.1 - 0.18 11.4 5.4 0.25 10.9 5.4 1.1 1 0 0 1 1 1 0 TMCO5 family Adaptin_binding PF10199.9 EER23309.1 - 0.18 12.4 5.2 0.27 11.9 5.2 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF2852 PF11014.8 EER23309.1 - 0.45 10.7 2.7 0.76 9.9 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) FlaC_arch PF05377.11 EER23309.1 - 1.5 9.2 5.1 0.29 11.6 1.3 1.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 EER23309.1 - 2.4 8.9 9.1 0.61 10.8 2.2 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Prominin PF05478.11 EER23309.1 - 2.6 5.9 4.4 3.5 5.5 4.4 1.1 1 0 0 1 1 1 0 Prominin DUF3431 PF11913.8 EER23310.1 - 2.5e-81 272.6 0.0 3.1e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Phosducin PF02114.16 EER23311.1 - 5e-11 42.0 0.4 7.1e-11 41.5 0.4 1.2 1 0 0 1 1 1 1 Phosducin U3_assoc_6 PF08640.11 EER23311.1 - 0.011 15.8 2.3 0.011 15.8 2.3 2.0 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Thioredoxin PF00085.20 EER23311.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Pinin_SDK_memA PF04696.13 EER23311.1 - 0.037 14.1 2.1 0.06 13.4 2.1 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region RNase_P_Rpp14 PF01900.19 EER23311.1 - 0.042 14.1 0.0 0.06 13.6 0.0 1.3 1 0 0 1 1 1 0 Rpp14/Pop5 family MobB PF03205.14 EER23311.1 - 0.14 12.0 0.6 9.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Adaptin_N PF01602.20 EER23312.1 - 1.6e-111 373.4 0.0 2.5e-111 372.8 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EER23312.1 - 2.9e-59 199.5 4.2 7.5e-59 198.2 4.2 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EER23312.1 - 1.1e-33 115.8 0.3 8e-33 113.0 0.1 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EER23312.1 - 5.5e-19 68.3 4.1 8.2e-13 48.6 0.2 5.6 4 1 2 6 6 6 2 HEAT repeats Cnd1 PF12717.7 EER23312.1 - 3.7e-09 36.8 5.8 0.026 14.6 0.0 5.1 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EER23312.1 - 0.00078 19.5 8.6 1.4 9.4 0.2 6.6 8 0 0 8 8 8 1 HEAT repeat DUF5010 PF16402.5 EER23312.1 - 0.17 10.7 0.0 0.9 8.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5010) HEAT_PBS PF03130.16 EER23312.1 - 0.31 11.8 8.0 5.1 8.1 0.1 5.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat CLASP_N PF12348.8 EER23312.1 - 0.35 10.4 2.3 3.1 7.3 0.1 3.0 3 0 0 3 3 3 0 CLASP N terminal HEAT_EZ PF13513.6 EER23312.1 - 1.3 9.6 5.2 1.4 9.5 1.6 3.1 3 0 0 3 3 3 0 HEAT-like repeat F-box-like PF12937.7 EER23313.1 - 5.2e-11 42.3 1.0 1.3e-10 41.0 1.0 1.7 1 0 0 1 1 1 1 F-box-like Hydrolase_6 PF13344.6 EER23314.1 - 1.4e-21 76.5 0.0 2.7e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER23314.1 - 9.2e-19 67.3 0.0 1.9e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EER23314.1 - 0.0043 17.4 0.1 1.6 9.0 0.0 3.1 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EER23314.1 - 0.013 15.6 0.0 0.083 13.0 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Apt1 PF10351.9 EER23314.1 - 0.041 12.7 0.8 0.055 12.3 0.0 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain PGP_phosphatase PF09419.10 EER23314.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Tom5 PF10642.9 EER23314.1 - 0.17 11.9 0.1 0.39 10.8 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase Aldo_ket_red PF00248.21 EER23315.1 - 6.2e-50 170.1 0.0 1.7e-49 168.6 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family ScsC_N PF18312.1 EER23315.1 - 0.048 13.5 0.1 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain TnpV PF14198.6 EER23315.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Hydrolase_6 PF13344.6 EER23316.1 - 3.3e-24 84.9 0.0 9.3e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER23316.1 - 1.1e-17 63.9 0.0 3.5e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EER23316.1 - 0.0028 17.9 0.0 3.2 8.0 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.20 EER23317.1 - 2.2e-63 214.2 0.0 4e-63 213.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EER23317.1 - 1.1e-09 38.2 0.1 2.1e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1570 PF07607.11 EER23317.1 - 0.061 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1570) tRNA_anti_2 PF13742.6 EER23317.1 - 0.082 13.1 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EER23317.1 - 0.095 12.2 0.1 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) SIP1 PF04938.12 EER23318.1 - 1.5e-12 47.7 0.0 1.8e-09 37.6 0.0 2.4 2 1 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) AAA_lid_10 PF17872.1 EER23318.1 - 0.078 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA lid domain Response_reg PF00072.24 EER23318.1 - 0.11 12.7 0.3 20 5.4 0.0 3.2 3 0 0 3 3 3 0 Response regulator receiver domain PX PF00787.24 EER23319.1 - 7.8e-17 61.3 0.0 8.6e-16 57.9 0.0 2.1 2 0 0 2 2 2 1 PX domain Syntaxin_2 PF14523.6 EER23319.1 - 1.6 9.1 5.9 8 6.9 2.5 2.8 2 1 0 2 2 2 0 Syntaxin-like protein Ku_PK_bind PF08785.11 EER23320.1 - 4.6e-38 130.0 0.0 1.1e-37 128.9 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 EER23320.1 - 6.1e-27 94.7 0.0 1.2e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA PF00092.28 EER23320.1 - 4.8e-05 23.7 0.0 9.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Ku_N PF03731.15 EER23320.1 - 0.0043 16.8 0.0 0.016 15.0 0.0 2.0 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Fe-ADH PF00465.19 EER23320.1 - 0.044 12.6 0.0 0.13 11.1 0.0 1.8 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF4149 PF13664.6 EER23321.1 - 8.1e-28 96.7 2.1 1.3e-27 96.1 1.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) GAS PF13851.6 EER23322.1 - 0.0021 17.4 0.5 0.0021 17.4 0.5 2.9 3 0 0 3 3 3 1 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EER23322.1 - 0.013 15.6 12.2 0.22 11.5 0.6 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF677 PF05055.12 EER23322.1 - 0.016 14.1 2.8 0.13 11.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF677) MAD PF05557.13 EER23322.1 - 0.021 13.2 8.6 0.029 12.8 3.0 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein XhlA PF10779.9 EER23322.1 - 0.024 14.9 2.2 0.97 9.7 0.1 2.7 2 0 0 2 2 2 0 Haemolysin XhlA LemA PF04011.12 EER23322.1 - 0.046 13.6 4.4 0.097 12.5 0.1 2.8 2 2 2 4 4 4 0 LemA family LXG PF04740.12 EER23322.1 - 0.094 12.4 3.5 0.28 10.9 0.2 2.5 2 0 0 2 2 2 0 LXG domain of WXG superfamily AAA_13 PF13166.6 EER23322.1 - 0.11 11.1 7.9 0.23 10.1 7.9 1.5 1 1 0 1 1 1 0 AAA domain Resolvase PF00239.21 EER23322.1 - 0.21 11.7 4.5 7.3 6.7 0.3 2.8 2 0 0 2 2 2 0 Resolvase, N terminal domain MLTR_LBD PF17765.1 EER23322.1 - 0.21 11.7 1.8 0.23 11.6 0.4 1.8 2 0 0 2 2 1 0 MmyB-like transcription regulator ligand binding domain FliJ PF02050.16 EER23322.1 - 0.24 11.7 6.0 0.79 10.0 2.7 3.0 2 1 0 2 2 2 0 Flagellar FliJ protein Apolipoprotein PF01442.18 EER23322.1 - 0.26 11.2 18.6 0.14 12.0 4.4 3.0 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Laminin_II PF06009.12 EER23322.1 - 0.29 11.1 9.3 0.18 11.8 1.1 2.9 2 1 0 2 2 2 0 Laminin Domain II Med21 PF11221.8 EER23322.1 - 0.42 10.9 8.2 0.21 11.8 4.0 2.5 2 1 0 2 2 2 0 Subunit 21 of Mediator complex UPF0242 PF06785.11 EER23322.1 - 0.45 10.6 12.4 2.2 8.3 4.4 3.0 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 EER23322.1 - 0.49 10.9 9.5 0.82 10.2 1.7 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 DLP_helical PF18709.1 EER23322.1 - 0.57 9.3 10.4 3.3 6.8 1.7 3.7 3 1 1 4 4 4 0 Dynamin-like helical domain BLOC1_2 PF10046.9 EER23322.1 - 0.59 10.5 10.6 0.37 11.1 0.6 3.1 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EER23322.1 - 0.64 10.1 5.3 31 4.6 0.1 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 EER23322.1 - 0.71 10.0 6.2 0.16 12.1 1.2 2.2 2 0 0 2 2 2 0 Tropomyosin like HrpB7 PF09486.10 EER23322.1 - 0.79 10.1 8.6 0.38 11.1 3.8 2.7 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF812 PF05667.11 EER23322.1 - 1.8 7.4 12.1 0.066 12.1 4.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Spc7 PF08317.11 EER23322.1 - 1.9 7.3 14.3 0.1 11.5 4.6 2.5 1 1 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.13 EER23322.1 - 2 7.6 5.7 13 4.9 0.4 2.7 2 1 0 2 2 2 0 TMPIT-like protein DUF745 PF05335.13 EER23322.1 - 2 8.1 12.7 3.1 7.5 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF745) ApoLp-III PF07464.11 EER23322.1 - 2.1 8.4 9.1 9.3 6.3 2.0 3.2 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Fib_alpha PF08702.10 EER23322.1 - 2.8 8.1 7.2 13 6.0 0.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 EER23322.1 - 3.1 8.3 6.4 58 4.2 0.1 4.4 3 2 2 5 5 4 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 EER23322.1 - 3.1 8.2 13.5 1.5 9.3 2.0 2.4 1 1 2 3 3 3 0 Fez1 DUF2730 PF10805.8 EER23322.1 - 4.1 7.6 17.4 1 9.5 0.8 4.9 4 2 2 6 6 5 0 Protein of unknown function (DUF2730) CLZ PF16526.5 EER23322.1 - 5.1 7.5 12.0 0.68 10.3 1.0 3.5 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sugar_tr PF00083.24 EER23323.1 - 9.3e-87 291.7 20.4 1.1e-86 291.5 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER23323.1 - 6.3e-15 54.9 30.5 6.3e-15 54.9 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HsbA PF12296.8 EER23324.1 - 0.00044 20.7 2.8 4.5 7.7 0.0 4.6 3 1 1 4 4 4 1 Hydrophobic surface binding protein A DUF1664 PF07889.12 EER23324.1 - 0.0009 19.3 8.3 6.2 6.9 0.0 4.5 3 1 1 4 4 4 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EER23324.1 - 0.054 13.5 11.7 16 5.5 0.4 5.0 1 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 EER23324.1 - 0.056 12.8 4.1 2 7.7 0.1 3.2 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein HBM PF16591.5 EER23324.1 - 0.063 12.7 1.2 6.1 6.2 0.2 3.0 2 1 0 2 2 2 0 Helical bimodular sensor domain NBD94 PF16830.5 EER23324.1 - 0.097 13.1 1.4 31 5.1 0.0 3.9 3 1 1 4 4 4 0 Nucleotide-Binding Domain 94 of RH DUF4446 PF14584.6 EER23324.1 - 0.26 11.3 2.5 32 4.5 0.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF4446) NPV_P10 PF05531.12 EER23324.1 - 0.51 10.8 17.4 5.3 7.6 0.6 5.4 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EER23324.1 - 0.98 9.9 3.0 75 3.8 0.0 4.8 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) CHASE3 PF05227.13 EER23324.1 - 1.9 8.4 10.2 0.15 12.0 0.2 3.9 4 2 1 5 5 5 0 CHASE3 domain TraF_2 PF13729.6 EER23324.1 - 2.9 7.2 6.3 3.3 7.0 0.2 3.0 3 0 0 3 3 3 0 F plasmid transfer operon, TraF, protein DUF2730 PF10805.8 EER23324.1 - 3.1 7.9 6.5 43 4.3 0.0 4.6 5 1 0 5 5 5 0 Protein of unknown function (DUF2730) TolA_bind_tri PF16331.5 EER23324.1 - 3.5 7.8 10.8 32 4.7 0.0 4.8 4 1 1 5 5 5 0 TolA binding protein trimerisation Seryl_tRNA_N PF02403.22 EER23324.1 - 4.1 7.7 10.7 12 6.1 0.0 4.9 2 1 3 5 5 5 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 EER23324.1 - 5 7.7 12.1 46 4.5 1.2 5.2 5 1 0 5 5 4 0 Cell division protein ZapB Topoisom_bac PF01131.20 EER23325.1 - 4.2e-94 315.9 0.0 9.6e-94 314.7 0.0 1.5 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EER23325.1 - 2.7e-20 72.5 0.0 7.5e-19 67.9 0.0 2.5 2 0 0 2 2 2 1 Toprim domain DUF1295 PF06966.12 EER23326.1 - 1e-36 126.6 14.1 2.4e-36 125.4 14.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EER23326.1 - 0.79 10.2 0.0 0.79 10.2 0.0 2.9 3 1 1 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Peptidase_M41 PF01434.18 EER23327.1 - 1.8e-66 223.7 0.0 4.3e-66 222.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EER23327.1 - 1.4e-42 145.2 0.0 4.4e-42 143.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER23327.1 - 9.6e-14 50.9 0.0 2.6e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EER23327.1 - 2e-09 37.8 0.5 5.7e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.14 EER23327.1 - 0.00052 20.0 0.0 0.0018 18.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EER23327.1 - 0.0023 18.3 0.4 0.15 12.4 0.1 3.2 3 0 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EER23327.1 - 0.0076 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EER23327.1 - 0.012 15.9 0.0 1.2 9.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain TIP49 PF06068.13 EER23327.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_17 PF13207.6 EER23327.1 - 0.031 14.7 0.0 0.3 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EER23327.1 - 0.043 13.6 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EER23327.1 - 0.074 13.2 0.0 0.28 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Terpene_synth PF01397.21 EER23327.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Focal_AT PF03623.13 EER23327.1 - 0.25 11.3 1.4 7.7 6.5 0.2 2.3 2 0 0 2 2 2 0 Focal adhesion targeting region Fungal_trans PF04082.18 EER23328.1 - 3.9e-26 91.7 0.0 1.1e-25 90.2 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER23328.1 - 4.8e-10 39.4 13.2 8.2e-10 38.6 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1117 PF06547.12 EER23328.1 - 1.6 9.3 3.7 4.8 7.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) tRNA-synt_2b PF00587.25 EER23329.1 - 3.1e-32 112.0 0.1 8.8e-30 104.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EER23329.1 - 2.9e-15 56.2 0.1 5.7e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EER23329.1 - 2.2e-13 50.1 0.0 3.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EER23329.1 - 0.00031 20.7 0.0 0.00063 19.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 EER23330.1 - 2e-38 131.6 0.0 2.6e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 EER23331.1 - 5.4e-13 49.5 0.1 5.4e-13 49.5 0.1 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase WSC PF01822.19 EER23332.1 - 1.6e-14 53.9 10.7 2.9e-14 53.0 10.7 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 EER23332.1 - 3.7e-08 32.6 1.3 9.3e-08 31.4 1.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EER23332.1 - 0.0095 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Podoplanin PF05808.11 EER23332.1 - 0.023 14.8 0.2 0.037 14.1 0.2 1.4 1 0 0 1 1 1 0 Podoplanin MGC-24 PF05283.11 EER23332.1 - 0.031 14.7 0.1 0.052 14.0 0.1 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Insulin_TMD PF17870.1 EER23332.1 - 0.064 13.3 0.6 0.13 12.3 0.6 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment TcpA PF05946.12 EER23333.1 - 0.12 12.5 0.0 0.18 12.0 0.0 1.4 1 1 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA APH PF01636.23 EER23334.1 - 0.027 14.4 0.1 1.8 8.4 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Blt1_C PF17183.4 EER23334.1 - 0.16 11.6 0.7 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 Get5 carboxyl domain Pkinase PF00069.25 EER23335.1 - 5e-07 29.4 0.0 8.2e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EER23335.1 - 0.00062 19.2 0.2 0.001 18.5 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER23335.1 - 0.034 14.1 0.1 0.05 13.5 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2370 PF10176.9 EER23338.1 - 3.6e-89 298.3 0.0 5.5e-89 297.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) FAM220 PF15487.6 EER23339.1 - 0.0074 16.0 0.7 0.0087 15.7 0.7 1.0 1 0 0 1 1 1 1 FAM220 family Pilt PF15453.6 EER23339.1 - 0.29 10.5 7.6 0.41 10.0 7.6 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions CoA_trans PF01144.23 EER23340.1 - 2.2e-105 350.9 0.5 8.6e-64 214.9 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase RPT PF13446.6 EER23341.1 - 7.4e-53 176.3 7.5 2.1e-18 66.0 0.2 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 EER23341.1 - 9.6e-47 159.6 0.1 3.5e-46 157.8 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER23341.1 - 5.1e-06 26.3 0.0 0.00061 19.5 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Tim17 PF02466.19 EER23342.1 - 2.6e-08 34.2 6.8 3.3e-08 33.9 5.8 1.7 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family PH PF00169.29 EER23343.1 - 7.6e-05 23.2 0.1 0.00043 20.8 0.1 2.3 2 0 0 2 2 2 1 PH domain P4Ha_N PF08336.11 EER23343.1 - 0.014 15.4 0.2 0.033 14.2 0.2 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region OmpH PF03938.14 EER23343.1 - 0.034 14.5 0.3 0.034 14.5 0.3 1.8 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF5344 PF17279.2 EER23343.1 - 0.087 13.4 0.2 12 6.5 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5344) RRM_1 PF00076.22 EER23344.1 - 1.2e-48 162.8 0.0 9.1e-18 63.9 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER23344.1 - 0.00037 20.1 0.0 0.17 11.5 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EER23344.1 - 0.0025 17.8 0.1 1.7 8.7 0.0 3.6 4 0 0 4 4 4 1 RNA binding motif SPOR PF05036.13 EER23344.1 - 0.014 15.8 0.0 5 7.6 0.0 3.4 3 0 0 3 3 3 0 Sporulation related domain Limkain-b1 PF11608.8 EER23344.1 - 0.021 14.9 1.1 13 6.0 0.1 4.0 3 2 0 3 3 3 0 Limkain b1 ATP-grasp_2 PF08442.10 EER23344.1 - 0.03 13.9 0.0 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain RRM_occluded PF16842.5 EER23344.1 - 0.065 13.1 0.0 0.9 9.4 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EER23344.1 - 0.11 12.4 0.0 8.8 6.1 0.0 2.7 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 EER23344.1 - 0.23 11.7 0.0 22 5.2 0.0 3.0 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter YoaP PF14268.6 EER23344.1 - 0.67 9.5 3.9 0.74 9.4 0.0 2.8 4 0 0 4 4 4 0 YoaP-like FmdA_AmdA PF03069.15 EER23345.1 - 6.3e-55 186.5 0.0 4.6e-32 111.3 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family CBM_19 PF03427.13 EER23345.1 - 0.047 13.7 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) BSP_II PF05432.11 EER23346.1 - 0.0084 15.9 0.2 0.012 15.3 0.2 1.3 1 1 0 1 1 1 1 Bone sialoprotein II (BSP-II) Utp14 PF04615.13 EER23346.1 - 0.35 9.4 2.1 0.44 9.1 2.1 1.1 1 0 0 1 1 1 0 Utp14 protein Sigma70_ner PF04546.13 EER23346.1 - 0.77 9.6 3.6 1.1 9.1 3.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 EER23346.1 - 1.1 8.9 9.2 1.9 8.2 9.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 EER23346.1 - 1.2 7.3 3.1 1.5 7.0 3.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EER23346.1 - 1.4 7.0 10.8 1.8 6.6 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 EER23346.1 - 1.8 6.7 5.7 2.2 6.4 5.7 1.1 1 0 0 1 1 1 0 Nop14-like family TPR_2 PF07719.17 EER23347.1 - 8.3e-07 28.7 18.6 7.3e-05 22.6 0.1 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 EER23347.1 - 0.00011 22.6 11.7 0.097 13.2 1.3 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER23347.1 - 0.00051 19.9 1.2 0.8 9.9 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER23347.1 - 0.00058 19.6 10.6 0.0023 17.7 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER23347.1 - 0.0015 18.2 7.2 0.88 9.3 0.1 5.4 5 0 0 5 5 5 1 TPR repeat TPR_16 PF13432.6 EER23347.1 - 0.0039 17.8 0.5 0.0039 17.8 0.5 6.6 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EER23347.1 - 0.021 15.0 1.2 3.2 8.2 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EER23347.1 - 0.23 11.7 4.5 2.3 8.4 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EER23347.1 - 4.5 8.4 28.5 0.32 11.9 0.2 7.2 7 1 0 7 7 7 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 EER23348.1 - 3.1e-11 44.0 0.1 5.1e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AA_permease_2 PF13520.6 EER23349.1 - 2e-52 178.4 35.0 2.6e-52 178.1 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER23349.1 - 2.8e-12 46.0 34.3 5e-12 45.2 34.3 1.3 1 1 0 1 1 1 1 Amino acid permease DUF456 PF04306.13 EER23350.1 - 0.049 13.9 6.1 0.35 11.2 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF456) APH PF01636.23 EER23352.1 - 8.2e-14 52.1 0.0 1.1e-12 48.4 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EER23352.1 - 0.00034 19.6 0.0 0.17 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 EER23352.1 - 0.028 13.7 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3435 PF11917.8 EER23353.1 - 3.1e-78 263.5 0.0 3.7e-78 263.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) COQ9 PF08511.11 EER23354.1 - 2.5e-25 88.0 0.1 4.4e-25 87.2 0.1 1.4 1 0 0 1 1 1 1 COQ9 TFX_C PF14601.6 EER23355.1 - 0.16 11.9 0.0 0.7 9.9 0.0 2.0 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term WD40 PF00400.32 EER23356.1 - 4.2e-08 33.7 1.4 0.39 11.7 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat DNA_methylase PF00145.17 EER23357.1 - 4.3e-35 121.6 0.0 7.5e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 EER23357.1 - 0.00025 20.9 2.0 1.1 9.1 0.0 3.1 2 1 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.8 EER23357.1 - 0.0019 18.2 0.0 0.0051 16.9 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain RasGAP PF00616.19 EER23358.1 - 7.5e-33 114.0 0.0 4.4e-22 78.8 0.0 3.2 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EER23358.1 - 2.1e-06 27.9 0.1 9.7e-06 25.8 0.1 2.1 1 1 0 1 1 1 1 C2 domain APG9 PF04109.16 EER23359.1 - 7.8e-211 701.2 13.8 9.1e-211 701.0 13.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Oxidored_FMN PF00724.20 EER23360.1 - 5.5e-66 223.2 0.0 3.8e-65 220.4 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 EER23360.1 - 0.09 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Glyco_hydro_47 PF01532.20 EER23361.1 - 8.2e-190 631.5 0.0 9.7e-190 631.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Cytochrom_B558a PF05038.13 EER23361.1 - 1.8 8.1 4.3 6.4 6.3 0.8 2.4 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF2013 PF09431.10 EER23362.1 - 1.1e-52 177.9 0.8 2.7e-52 176.6 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) DUF3818 PF12825.7 EER23362.1 - 0.028 13.4 0.2 0.068 12.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) Glyco_hydro_17 PF00332.18 EER23363.1 - 3.6e-06 26.8 1.0 3.6e-06 26.8 1.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 YppG PF14179.6 EER23363.1 - 0.11 13.2 0.1 0.42 11.3 0.1 1.9 2 0 0 2 2 2 0 YppG-like protein Peptidase_M24 PF00557.24 EER23364.1 - 4.7e-10 39.5 0.1 6.4e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF5082 PF16888.5 EER23364.1 - 0.18 12.1 0.4 0.3 11.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) Aminotran_1_2 PF00155.21 EER23365.1 - 2.6e-35 122.3 0.0 3.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EER23365.1 - 0.0021 16.7 0.0 0.0033 16.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.15 EER23366.1 - 0 1386.4 0.0 0 1386.0 0.0 1.1 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EER23366.1 - 1.7e-44 151.3 0.3 4.6e-44 149.9 0.3 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.14 EER23367.1 - 2.1e-134 447.7 8.7 2.7e-134 447.4 8.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EER23367.1 - 2.6e-26 92.1 2.5 6.8e-26 90.8 2.5 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EER23367.1 - 5.1e-05 22.8 0.3 0.0011 18.5 0.3 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2812 PF11193.8 EER23367.1 - 0.075 13.3 0.1 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) Peptidase_S8 PF00082.22 EER23368.1 - 4e-32 111.7 14.9 2.2e-31 109.2 14.9 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER23368.1 - 3.3e-10 40.5 0.0 5.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3553 PF12073.8 EER23368.1 - 0.054 13.2 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) HSP20 PF00011.21 EER23369.1 - 3.6e-18 65.6 0.0 2.5e-17 62.9 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EER23369.1 - 8.8e-06 25.2 0.0 3.1e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA SprT-like PF10263.9 EER23370.1 - 3.5e-41 139.6 0.4 5.7e-41 138.9 0.4 1.3 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EER23370.1 - 4e-10 39.4 6.6 8e-10 38.5 6.6 1.6 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF4379 PF14311.6 EER23370.1 - 0.048 14.0 3.0 0.17 12.3 3.0 2.0 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 EER23370.1 - 0.3 11.3 2.8 0.67 10.1 2.8 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Mog1 PF04603.12 EER23371.1 - 9.8e-32 110.2 0.0 1.4e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NYN PF01936.18 EER23372.1 - 1.8e-05 25.2 0.0 0.00053 20.5 0.0 2.5 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.12 EER23373.1 - 1.7e-28 98.8 6.5 1.7e-28 98.8 6.5 1.5 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.7 EER23373.1 - 0.12 13.0 4.1 0.098 13.2 2.6 1.8 1 1 0 1 1 1 0 YtxH-like protein Tombus_movement PF05318.12 EER23373.1 - 0.36 11.7 4.3 0.4 11.6 3.8 1.4 1 1 0 1 1 1 0 Tombusvirus movement protein Snapin_Pallidin PF14712.6 EER23374.1 - 0.0071 16.7 0.7 0.0071 16.7 0.7 3.7 4 1 0 4 4 4 1 Snapin/Pallidin DUF4407 PF14362.6 EER23374.1 - 0.032 13.6 3.9 0.025 13.9 2.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Cauli_AT PF03233.13 EER23374.1 - 0.034 14.1 0.7 0.034 14.1 0.7 2.3 2 1 0 2 2 2 0 Aphid transmission protein GAGBD PF16828.5 EER23374.1 - 0.089 12.9 3.2 0.25 11.4 0.8 2.2 1 1 1 2 2 2 0 GAG-binding domain on surface antigen GAS PF13851.6 EER23374.1 - 0.47 9.8 13.7 0.082 12.2 1.7 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding COG6 PF06419.11 EER23375.1 - 1.7e-207 690.5 0.1 2e-207 690.3 0.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF4698 PF15769.5 EER23375.1 - 0.015 14.4 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Laminin_II PF06009.12 EER23375.1 - 0.042 13.9 0.4 0.14 12.1 0.4 2.0 1 0 0 1 1 1 0 Laminin Domain II COG2 PF06148.11 EER23375.1 - 0.062 13.4 2.7 0.098 12.7 0.4 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1484 PF07363.11 EER23375.1 - 0.096 13.7 0.1 31 5.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) Transcrip_act PF04949.13 EER23375.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator NIF3 PF01784.18 EER23376.1 - 2.9e-56 190.8 0.0 3.6e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.18 EER23377.1 - 3.2e-18 65.8 0.0 5.8e-18 64.9 0.0 1.5 1 1 0 1 1 1 1 BolA-like protein QLQ PF08880.11 EER23377.1 - 0.036 13.8 0.4 0.064 13.0 0.4 1.4 1 0 0 1 1 1 0 QLQ MFS_1 PF07690.16 EER23378.1 - 4.7e-38 131.0 63.2 1.7e-37 129.2 63.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER23378.1 - 2.3e-13 49.5 24.6 3.3e-13 48.9 24.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER23378.1 - 2.2e-12 46.6 15.7 2.2e-12 46.6 15.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Chal_sti_synt_N PF00195.19 EER23379.1 - 2.7e-19 69.5 0.0 4.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 EER23379.1 - 3.2e-16 59.7 0.0 3.6e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 EER23379.1 - 0.0011 18.4 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EER23379.1 - 0.0073 16.5 0.0 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HSF_DNA-bind PF00447.17 EER23380.1 - 5.8e-31 107.0 3.3 1e-30 106.2 0.9 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 EER23380.1 - 3.1e-22 78.9 0.0 6e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain W2 PF02020.18 EER23381.1 - 7.5e-18 64.5 5.1 7.5e-18 64.5 5.1 2.8 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EER23381.1 - 1.9e-11 43.2 12.4 0.00014 21.4 2.5 3.7 1 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EER23381.1 - 9e-07 28.7 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.6 EER23381.1 - 0.00082 19.1 15.8 0.03 14.1 3.4 3.4 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EER23381.1 - 0.036 12.2 2.6 0.23 9.5 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 EER23381.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain IBR PF01485.21 EER23382.1 - 3.1e-20 72.1 52.9 2.2e-11 43.8 5.7 4.7 4 1 1 5 5 5 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EER23382.1 - 0.00014 21.6 6.1 0.00014 21.6 6.1 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER23382.1 - 0.00084 19.6 8.6 0.00084 19.6 8.6 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER23382.1 - 0.0052 16.6 6.8 0.0052 16.6 6.8 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER23382.1 - 0.014 15.3 10.2 0.014 15.3 10.2 3.7 3 0 0 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EER23382.1 - 0.026 14.5 5.2 0.026 14.5 5.2 3.9 3 1 0 3 3 3 0 RING-type zinc-finger Trp_syntA PF00290.20 EER23382.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Mito_carr PF00153.27 EER23383.1 - 3e-65 216.2 5.9 3.2e-22 78.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EER23383.1 - 0.03 13.5 1.9 0.11 11.6 0.2 2.5 2 1 1 3 3 3 0 Gammaproteobacterial serine protease AAA PF00004.29 EER23384.1 - 2e-37 128.6 0.1 5e-37 127.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EER23384.1 - 2.8e-08 33.6 0.0 3e-06 27.1 0.0 3.3 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EER23384.1 - 7.6e-07 28.8 0.0 2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EER23384.1 - 1.4e-05 25.3 0.3 0.00019 21.8 0.3 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EER23384.1 - 5e-05 23.1 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EER23384.1 - 7.4e-05 23.2 0.8 0.0041 17.5 0.1 3.2 3 1 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 EER23384.1 - 0.00029 20.8 0.0 0.00084 19.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EER23384.1 - 0.0017 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EER23384.1 - 0.0021 17.8 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.13 EER23384.1 - 0.0041 16.4 0.0 0.0068 15.6 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EER23384.1 - 0.0041 16.5 0.1 0.0084 15.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EER23384.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EER23384.1 - 0.017 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EER23384.1 - 0.021 15.0 0.0 0.053 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EER23384.1 - 0.06 12.9 2.1 0.18 11.4 0.1 2.5 2 1 1 3 3 3 0 AAA domain AAA_7 PF12775.7 EER23384.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EER23384.1 - 0.1 12.5 0.2 0.25 11.3 0.0 1.8 2 0 0 2 2 1 0 NACHT domain AAA_19 PF13245.6 EER23384.1 - 0.1 12.9 0.0 0.27 11.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EER23384.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EER23384.1 - 0.12 13.0 0.0 0.34 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EER23384.1 - 0.14 11.5 0.0 5.5 6.3 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein Ntox28 PF15605.6 EER23384.1 - 0.15 12.3 0.7 21 5.4 0.1 2.6 2 0 0 2 2 2 0 Bacterial toxin 28 AAA_28 PF13521.6 EER23384.1 - 0.26 11.5 1.9 0.64 10.3 0.0 2.4 3 0 0 3 3 2 0 AAA domain Ribosomal_S17 PF00366.20 EER23385.1 - 2.3e-08 34.0 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 GlyL_C PF12524.8 EER23385.1 - 0.061 13.5 1.1 0.17 12.1 1.1 1.7 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal Glyco_transf_20 PF00982.21 EER23386.1 - 2.7e-201 669.3 0.0 3.1e-201 669.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EER23386.1 - 0.035 13.8 0.2 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain BLACT_WH PF17778.1 EER23387.1 - 1.2e-18 66.8 1.2 2.5e-18 65.8 0.1 2.1 2 0 0 2 2 2 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EER23387.1 - 9.1e-17 61.7 2.2 8.3e-15 55.3 2.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EER23387.1 - 4.2e-06 26.4 0.2 8.8e-06 25.4 0.2 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EER23387.1 - 0.0055 16.6 0.1 0.0087 16.0 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Aconitase PF00330.20 EER23388.1 - 2.2e-150 501.7 0.0 2.8e-150 501.4 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EER23388.1 - 1.8e-44 151.3 0.0 3e-44 150.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Fungal_trans_2 PF11951.8 EER23389.1 - 1e-05 24.6 2.2 1.8e-05 23.7 2.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER23389.1 - 0.37 11.0 12.2 0.16 12.2 2.0 2.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5353 PF17304.2 EER23390.1 - 0.018 14.8 1.7 0.032 14.0 0.1 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5353) CD20 PF04103.15 EER23390.1 - 0.034 14.3 8.2 0.44 10.6 1.2 2.3 1 1 1 2 2 2 0 CD20-like family BCLP PF12304.8 EER23390.1 - 0.14 11.7 3.3 0.13 11.8 1.7 1.7 1 1 1 2 2 2 0 Beta-casein like protein DUF4225 PF13988.6 EER23390.1 - 1 8.9 5.2 0.62 9.6 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) zf-C2H2_jaz PF12171.8 EER23391.1 - 7e-11 42.1 3.3 1.1e-10 41.5 3.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EER23391.1 - 0.00051 20.0 1.3 0.00085 19.3 1.3 1.3 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EER23391.1 - 0.0038 17.9 0.7 0.0077 17.0 0.7 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 EER23391.1 - 0.0049 17.2 2.0 0.0083 16.5 2.0 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EER23391.1 - 0.012 15.9 1.1 0.051 13.9 0.5 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EER23391.1 - 0.019 15.4 0.6 0.035 14.6 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-U1 PF06220.12 EER23391.1 - 0.035 13.9 0.8 0.084 12.7 0.8 1.6 1 0 0 1 1 1 0 U1 zinc finger Drc1-Sld2 PF11719.8 EER23391.1 - 0.051 13.1 0.6 0.053 13.1 0.6 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein zf-SCNM1 PF15803.5 EER23391.1 - 0.071 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of sodium channel modifier 1 Ribosomal_L2 PF00181.23 EER23391.1 - 0.25 11.3 1.4 0.37 10.8 0.1 1.8 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain Mito_carr PF00153.27 EER23392.1 - 4.9e-50 167.4 0.9 2.5e-20 72.2 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein SNF2_N PF00176.23 EER23393.1 - 2.3e-57 194.3 0.0 3.3e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EER23393.1 - 5e-56 189.7 1.0 2.5e-55 187.4 1.3 2.0 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 EER23393.1 - 3.2e-16 59.6 0.0 9.1e-16 58.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER23393.1 - 1.7e-05 24.9 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EER23393.1 - 0.002 17.4 0.0 0.015 14.5 0.0 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EER23393.1 - 0.098 12.3 0.0 0.31 10.7 0.0 1.8 2 1 0 2 2 2 0 SWI2/SNF2 ATPase Vac14_Fig4_bd PF11916.8 EER23394.1 - 3.7e-81 271.1 9.6 3.7e-81 271.1 9.6 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EER23394.1 - 2.6e-42 143.3 0.0 8.2e-40 135.3 0.0 3.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EER23394.1 - 1.4e-07 31.8 2.2 0.074 13.6 0.1 5.6 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EER23394.1 - 0.0006 19.9 1.3 6.1 7.4 0.1 6.3 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 EER23394.1 - 0.0033 17.5 1.3 0.052 13.6 0.4 3.1 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EER23394.1 - 0.006 15.7 0.6 0.67 9.0 0.0 3.3 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Arm PF00514.23 EER23394.1 - 0.017 15.1 0.2 9.1 6.5 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat SPX PF03105.19 EER23394.1 - 6.6 6.5 7.8 0.68 9.8 3.3 1.6 2 0 0 2 2 2 0 SPX domain ABC_membrane PF00664.23 EER23395.1 - 1.4e-42 146.3 9.9 1.7e-42 146.0 9.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EER23395.1 - 4.1e-35 121.3 0.0 8.3e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EER23395.1 - 1.4e-05 24.6 0.0 0.01 15.3 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EER23395.1 - 0.00032 21.1 0.0 0.00082 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EER23395.1 - 0.00086 19.6 0.0 0.0032 17.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EER23395.1 - 0.0039 17.0 2.7 0.0084 16.0 0.0 2.5 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EER23395.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EER23395.1 - 0.011 15.4 0.5 8.1 6.1 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.6 EER23395.1 - 0.015 15.8 0.6 0.037 14.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EER23395.1 - 0.037 13.7 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EER23395.1 - 0.04 13.9 0.0 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EER23395.1 - 0.042 13.8 0.0 0.084 12.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 EER23395.1 - 0.05 14.0 0.0 0.36 11.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EER23395.1 - 0.058 13.3 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 EER23395.1 - 0.072 13.6 0.0 1 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EER23395.1 - 0.12 11.3 0.0 0.24 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 EER23395.1 - 0.12 12.6 0.0 0.42 10.9 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EER23395.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AIM24 PF01987.17 EER23396.1 - 2.4e-48 164.6 0.0 2.9e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Epiglycanin_TR PF05647.11 EER23396.1 - 0.067 13.1 4.9 0.29 11.1 1.1 2.5 2 0 0 2 2 2 0 Tandem-repeating region of mucin, epiglycanin-like PCI PF01399.27 EER23397.1 - 1.4e-10 41.6 0.0 2.6e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EER23397.1 - 6.3e-05 22.5 0.8 0.00013 21.4 0.8 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Epimerase PF01370.21 EER23398.1 - 3.8e-14 52.8 0.1 1.1e-13 51.2 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EER23398.1 - 4e-12 46.4 0.0 6.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EER23398.1 - 1.6e-11 44.3 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EER23398.1 - 8.7e-11 41.3 0.1 1.5e-10 40.5 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EER23398.1 - 2.7e-07 30.3 0.2 1.7e-06 27.7 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EER23398.1 - 4.2e-06 26.1 0.0 0.00011 21.5 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EER23398.1 - 5.9e-05 22.6 0.0 8.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EER23398.1 - 0.00021 20.5 0.1 0.0097 15.1 0.2 2.7 1 1 1 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 EER23398.1 - 0.0044 16.6 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HIM1 PF08732.10 EER23398.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 HIM1 SWI2_SNF2 PF18766.1 EER23398.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase NAD_binding_2 PF03446.15 EER23398.1 - 0.16 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 EER23398.1 - 0.2 11.6 0.0 1.1 9.1 0.0 2.2 2 1 0 2 2 2 0 KR domain HEM4 PF02602.15 EER23399.1 - 6e-37 127.2 0.0 1.5e-36 125.9 0.0 1.5 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.25 EER23400.1 - 1.4e-67 227.9 0.0 1.7e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23400.1 - 3.6e-32 111.7 0.0 4.7e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EER23400.1 - 0.00032 20.1 0.2 0.00052 19.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EER23400.1 - 0.0035 16.3 0.1 0.006 15.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EER23400.1 - 0.0094 15.3 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EER23400.1 - 0.038 13.9 0.2 0.066 13.1 0.2 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EER23400.1 - 0.062 12.4 0.1 0.091 11.8 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.15 EER23401.1 - 1.8e-70 237.3 0.0 3.4e-70 236.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EER23401.1 - 8.8e-24 83.3 0.0 3.1e-23 81.6 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EER23401.1 - 3.5e-17 62.9 0.1 7.9e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EER23401.1 - 2.1e-16 59.7 4.3 3.8e-16 58.9 4.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EER23401.1 - 1.9e-07 30.9 0.0 3.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EER23401.1 - 0.048 13.1 0.1 0.095 12.1 0.1 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain VWA_2 PF13519.6 EER23401.1 - 0.07 13.8 0.1 48 4.7 0.0 3.3 3 0 0 3 3 3 0 von Willebrand factor type A domain Kinesin PF00225.23 EER23402.1 - 1.4e-81 274.0 0.1 2.7e-81 273.1 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EER23402.1 - 2.1e-20 73.2 0.0 4.5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 EER23402.1 - 0.036 14.0 0.1 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EER23402.1 - 0.049 14.3 0.1 15 6.3 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_3 PF12836.7 EER23402.1 - 0.068 13.4 0.3 18 5.7 0.1 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif RTA1 PF04479.13 EER23403.1 - 1.2e-38 132.8 2.7 1.8e-38 132.2 2.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF3995 PF13160.6 EER23403.1 - 0.098 13.0 1.9 0.25 11.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) Gaa1 PF04114.14 EER23405.1 - 1.3e-181 605.0 2.5 1.6e-181 604.7 2.5 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Ytp1 PF10355.9 EER23406.1 - 7.4e-118 392.8 10.9 1.2e-117 392.1 10.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EER23406.1 - 2.7e-28 97.8 8.5 2.7e-28 97.8 8.5 3.0 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) UCH PF00443.29 EER23407.1 - 3.6e-53 180.7 0.5 4.6e-53 180.3 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER23407.1 - 2.7e-21 76.5 8.4 5.2e-21 75.6 6.6 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EER23407.1 - 5.5e-06 26.6 0.3 5.5e-06 26.6 0.3 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zinc_ribbon_2 PF13240.6 EER23407.1 - 0.072 12.8 3.3 7.1 6.5 1.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EER23407.1 - 0.17 11.8 2.0 1.3 9.0 0.0 3.1 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DASH_Dam1 PF08653.10 EER23408.1 - 2e-29 101.2 2.5 2.7e-29 100.7 2.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.20 EER23409.1 - 2.8e-41 140.9 0.0 1.1e-40 139.0 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EER23409.1 - 4.5e-15 55.6 0.1 1.4e-14 54.0 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EER23409.1 - 2.6e-06 27.6 0.0 4.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.23 EER23410.1 - 7.9e-17 61.8 0.0 1.1e-16 61.3 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EER23410.1 - 6.5e-09 36.3 0.0 8.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EER23410.1 - 0.075 12.9 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Peptidase_M20 PF01546.28 EER23411.1 - 8.2e-27 94.3 0.1 1.4e-26 93.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EER23411.1 - 0.00023 21.0 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EER23411.1 - 0.024 14.4 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 S10_plectin PF03501.15 EER23412.1 - 1.3e-42 143.8 0.1 1.6e-42 143.5 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Sde2_N_Ubi PF13019.6 EER23413.1 - 7.4e-66 221.0 0.4 1.3e-65 220.2 0.4 1.4 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain MMR_HSR1 PF01926.23 EER23414.1 - 8.4e-06 25.8 0.0 0.0002 21.4 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER23414.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase tRNA-synt_1 PF00133.22 EER23415.1 - 3e-37 128.1 0.0 7.3e-27 93.9 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EER23415.1 - 4e-18 65.3 0.0 3.9e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EER23415.1 - 4.7e-13 49.4 0.2 1.2e-12 48.0 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EER23415.1 - 8.5e-08 31.9 0.0 2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EER23415.1 - 0.023 13.6 0.0 0.075 11.9 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetases class I (K) L51_S25_CI-B8 PF05047.16 EER23416.1 - 6.8e-15 54.7 0.0 1.2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Spore_III_AB PF09548.10 EER23416.1 - 0.1 12.7 1.9 0.18 11.9 1.9 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF1751 PF08551.10 EER23417.1 - 3.9e-27 94.7 2.4 7.1e-27 93.9 2.4 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EER23417.1 - 0.0022 18.0 8.2 0.0047 17.0 8.2 1.5 1 0 0 1 1 1 1 Rhomboid family TSKS PF15358.6 EER23417.1 - 0.14 10.5 1.4 0.2 10.0 1.4 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate MFS_1 PF07690.16 EER23419.1 - 6e-25 87.9 43.8 7.1e-19 67.9 23.5 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 EER23420.1 - 1.2e-09 38.6 7.8 0.024 15.5 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23420.1 - 1.7e-07 31.4 0.0 0.04 14.2 0.0 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER23420.1 - 0.00053 19.9 0.0 0.19 11.6 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EER23420.1 - 0.066 11.2 0.0 0.098 10.6 0.0 1.4 1 0 0 1 1 1 0 IKI3 family NTS_2 PF15448.6 EER23420.1 - 0.16 12.4 0.2 0.42 11.0 0.2 1.6 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein Chorismate_bind PF00425.18 EER23421.1 - 3.8e-92 308.5 0.0 5.7e-92 307.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EER23421.1 - 3.1e-28 98.8 0.0 2e-24 86.4 0.0 3.5 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region POR PF01558.18 EER23421.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase ENTH PF01417.20 EER23422.1 - 1e-48 164.5 0.0 1.5e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EER23422.1 - 0.00026 20.1 0.0 0.00043 19.4 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 EER23422.1 - 0.00067 20.0 39.1 0.00067 20.0 39.1 5.3 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) UIM PF02809.20 EER23422.1 - 0.019 14.8 6.8 0.032 14.2 1.5 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif WD40 PF00400.32 EER23423.1 - 8.8e-51 168.8 20.7 1e-07 32.5 0.3 8.7 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23423.1 - 1.4e-14 54.1 0.0 0.0042 17.4 0.1 4.9 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER23423.1 - 1.6e-08 33.7 0.0 0.001 17.9 0.0 4.1 5 0 0 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EER23423.1 - 0.0011 17.8 0.0 2.8 6.6 0.0 3.2 3 0 0 3 3 3 2 Nup133 N terminal like bZIP_2 PF07716.15 EER23423.1 - 0.065 13.3 0.2 0.14 12.3 0.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Pox_A_type_inc PF04508.12 EER23423.1 - 0.17 11.8 0.2 0.38 10.7 0.2 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Cnd1 PF12717.7 EER23424.1 - 5e-05 23.4 0.8 1.4 9.0 0.0 3.4 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EER23424.1 - 5.5e-05 23.1 0.7 2.5 8.6 0.1 5.8 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.20 EER23424.1 - 0.00016 20.4 2.0 0.0031 16.2 2.0 2.4 1 1 0 1 1 1 1 Adaptin N terminal region CLASP_N PF12348.8 EER23424.1 - 0.00019 21.1 0.7 0.047 13.3 0.3 3.3 2 1 0 2 2 2 1 CLASP N terminal MMS19_N PF14500.6 EER23424.1 - 0.0013 18.4 1.6 0.033 13.8 0.1 3.1 2 2 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF4407 PF14362.6 EER23424.1 - 0.0015 18.0 11.0 0.019 14.3 4.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4407) TAN PF11640.8 EER23424.1 - 0.004 17.3 0.4 0.004 17.3 0.4 3.0 2 1 0 2 2 1 1 Telomere-length maintenance and DNA damage repair Fez1 PF06818.15 EER23424.1 - 0.014 15.9 5.3 0.014 15.9 5.3 1.9 2 0 0 2 2 1 0 Fez1 Golgin_A5 PF09787.9 EER23424.1 - 0.093 12.2 12.6 0.22 11.0 12.6 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Proteasom_PSMB PF10508.9 EER23424.1 - 0.12 10.9 0.0 0.12 10.9 0.0 2.5 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Atg14 PF10186.9 EER23424.1 - 0.17 10.9 5.9 0.36 9.9 5.9 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 EER23424.1 - 0.21 11.9 17.9 0.51 10.7 10.9 3.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GLYCAM-1 PF05242.11 EER23424.1 - 0.31 11.1 6.9 0.31 11.2 4.9 2.0 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Spc7 PF08317.11 EER23424.1 - 0.49 9.2 14.1 1.2 7.9 14.1 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein HAUS-augmin3 PF14932.6 EER23424.1 - 0.49 9.9 11.2 0.69 9.4 8.3 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 V-ATPase_H_C PF11698.8 EER23424.1 - 0.62 10.2 4.1 19 5.4 0.0 3.6 3 1 1 4 4 3 0 V-ATPase subunit H ParE_toxin PF05016.15 EER23424.1 - 1.1 10.0 4.8 3.4 8.3 0.5 3.4 3 0 0 3 3 2 0 ParE toxin of type II toxin-antitoxin system, parDE UPF0242 PF06785.11 EER23424.1 - 1.2 9.2 10.3 3.8 7.6 10.3 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EER23424.1 - 1.6 8.2 10.1 0.087 12.4 3.8 2.0 2 1 0 2 2 2 0 Exonuclease VII, large subunit DUF724 PF05266.14 EER23424.1 - 2 8.2 10.6 4.9 6.9 10.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Cas_Cmr5 PF09701.10 EER23424.1 - 2.3 8.5 8.9 1 9.7 0.3 3.5 3 1 0 3 3 3 0 CRISPR-associated protein (Cas_Cmr5) FapA PF03961.13 EER23424.1 - 2.8 6.5 6.5 4.8 5.7 6.5 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 EER23424.1 - 3.2 7.8 17.2 9.2 6.3 17.2 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 EER23424.1 - 5 6.3 16.5 2.7 7.3 4.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TT_ORF2 PF02957.15 EER23424.1 - 6.1 7.8 7.8 5.1 8.0 4.9 2.4 2 0 0 2 2 1 0 TT viral ORF2 COG5 PF10392.9 EER23424.1 - 7.3 6.8 9.1 7.7 6.7 7.5 1.9 2 0 0 2 2 1 0 Golgi transport complex subunit 5 Ribosomal_L7Ae PF01248.26 EER23425.1 - 5.6e-22 77.3 0.4 9e-22 76.6 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 EER23425.1 - 0.17 10.9 0.2 0.23 10.4 0.2 1.2 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Clat_adaptor_s PF01217.20 EER23426.1 - 4e-43 146.7 0.0 9e-43 145.6 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.23 EER23427.1 - 6e-20 71.4 0.0 9.8e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EER23427.1 - 1.9e-07 31.3 0.1 0.00049 20.2 0.3 2.3 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.16 EER23427.1 - 3.3e-06 26.6 0.0 5.1e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 EER23427.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EER23427.1 - 0.00019 21.1 0.0 0.0011 18.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EER23427.1 - 0.00058 19.4 0.0 0.00084 18.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.13 EER23427.1 - 0.0022 17.1 0.0 0.0046 16.1 0.0 1.4 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 EER23427.1 - 0.0068 16.3 1.4 0.036 14.0 1.0 2.2 2 1 0 2 2 2 1 RsgA GTPase Septin PF00735.18 EER23427.1 - 0.017 14.4 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 EER23427.1 - 0.15 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EER23427.1 - 0.2 11.9 0.1 0.5 10.6 0.0 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 EER23428.1 - 1.1e-38 130.5 19.2 9.2e-06 26.3 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 EER23428.1 - 1.7e-08 34.1 0.4 4.5e-08 32.8 0.4 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EER23428.1 - 2.5e-07 30.9 0.7 2 8.8 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EER23428.1 - 2.6e-07 30.4 0.1 6.2e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EER23428.1 - 0.0002 20.2 4.1 5.5 5.5 0.0 4.8 3 1 2 5 5 5 3 Nucleoporin Nup120/160 F-box_4 PF15966.5 EER23428.1 - 0.0014 18.5 0.1 0.0037 17.1 0.1 1.7 1 0 0 1 1 1 1 F-box PQQ_2 PF13360.6 EER23428.1 - 0.0053 16.4 0.1 2.5 7.6 0.0 2.8 2 1 0 2 2 2 2 PQQ-like domain SGL PF08450.12 EER23428.1 - 0.032 13.8 0.2 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region WD40_like PF17005.5 EER23428.1 - 0.035 13.4 0.0 4.5 6.5 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain CPSF_A PF03178.15 EER23428.1 - 0.2 10.9 0.0 2.1 7.6 0.0 2.4 3 0 0 3 3 3 0 CPSF A subunit region HORMA PF02301.18 EER23429.1 - 3.1e-69 232.8 0.0 5.1e-69 232.1 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 EER23429.1 - 7.6e-05 22.5 8.8 0.00016 21.5 8.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EER23429.1 - 0.00093 18.7 2.4 0.002 17.7 2.4 1.6 1 0 0 1 1 1 1 PHD-finger Cu_amine_oxid PF01179.20 EER23430.1 - 2.3e-123 412.1 0.2 2.9e-123 411.8 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.10 EER23430.1 - 1.7e-31 107.8 0.2 3.2e-31 106.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.16 EER23430.1 - 1.3e-08 34.9 0.0 2.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Nuc_sug_transp PF04142.15 EER23432.1 - 7e-80 268.5 6.0 9.3e-80 268.1 6.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EER23432.1 - 0.0041 17.3 28.8 0.005 17.0 7.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family TMEM234 PF10639.9 EER23432.1 - 0.014 15.4 0.4 0.063 13.3 0.5 2.0 2 0 0 2 2 2 0 Putative transmembrane family 234 EmrE PF13536.6 EER23432.1 - 0.024 14.2 0.4 0.024 14.2 0.4 2.6 2 1 1 3 3 3 0 Putative multidrug resistance efflux transporter TPT PF03151.16 EER23432.1 - 0.14 11.5 10.2 0.048 13.0 3.0 2.3 2 0 0 2 2 2 0 Triose-phosphate Transporter family Sec63 PF02889.16 EER23433.1 - 5.9e-32 110.8 0.0 1e-31 110.0 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EER23433.1 - 6.2e-25 88.0 0.1 1.7e-24 86.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EER23433.1 - 2.7e-13 50.3 0.0 6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EER23433.1 - 8.3e-07 29.3 0.0 9.2e-06 26.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EER23433.1 - 0.0024 18.2 0.0 0.0086 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EER23433.1 - 0.015 15.9 0.1 0.034 14.8 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain SWI2_SNF2 PF18766.1 EER23433.1 - 0.026 14.2 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_19 PF13245.6 EER23433.1 - 0.029 14.7 0.0 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EER23433.1 - 0.08 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EER23433.1 - 0.087 12.3 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF1664 PF07889.12 EER23434.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Acid_PPase PF12689.7 EER23435.1 - 2.5e-69 232.5 0.0 2.9e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase DUF4091 PF13320.6 EER23435.1 - 0.098 12.8 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) Hexapep PF00132.24 EER23436.1 - 2.1e-09 36.7 8.1 0.0034 17.0 0.0 4.5 3 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EER23436.1 - 0.0077 16.0 2.8 0.0077 16.0 2.8 3.2 4 1 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase RAM PF15320.6 EER23436.1 - 0.15 12.7 0.5 0.24 12.0 0.5 1.3 1 0 0 1 1 1 0 mRNA cap methylation, RNMT-activating mini protein Acetyltransf_1 PF00583.25 EER23437.1 - 2.1e-16 60.2 0.0 2.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER23437.1 - 2.9e-11 43.6 0.0 4.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER23437.1 - 1.4e-10 41.2 0.0 2e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EER23437.1 - 8.4e-06 26.5 0.0 1.1e-05 26.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER23437.1 - 3.9e-05 23.7 0.1 0.00016 21.8 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER23437.1 - 0.0016 18.6 0.0 0.0027 17.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EER23437.1 - 0.002 18.0 0.0 0.005 16.8 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_13 PF13880.6 EER23437.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TPR_MLP1_2 PF07926.12 EER23438.1 - 1.3e-38 132.0 29.4 1.3e-38 132.0 29.4 17.7 5 5 12 17 17 17 6 TPR/MLP1/MLP2-like protein Taxilin PF09728.9 EER23438.1 - 5.8e-05 22.4 22.3 5.8e-05 22.4 22.3 9.5 2 2 6 9 9 9 3 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 EER23438.1 - 0.0046 17.0 7.9 0.0046 17.0 7.9 16.3 6 2 9 16 16 16 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 EER23438.1 - 0.0072 16.6 13.0 0.0072 16.6 13.0 16.9 3 3 12 17 17 17 2 JNK_SAPK-associated protein-1 TFIIE_beta PF02186.15 EER23439.1 - 1.3e-23 83.1 0.2 5e-23 81.2 0.0 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 EER23439.1 - 5.7e-23 80.4 0.5 1.5e-22 79.0 0.2 1.9 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 DUF1631 PF07793.11 EER23439.1 - 0.022 13.2 4.5 0.0094 14.4 1.4 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1631) DUF3446 PF11928.8 EER23439.1 - 0.26 11.6 4.1 0.44 10.9 4.1 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain DHBP_synthase PF00926.19 EER23440.1 - 4.2e-83 277.6 0.0 4.9e-83 277.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.7 EER23441.1 - 2.1e-09 37.2 0.1 4.4e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER23441.1 - 7.5e-05 22.5 0.6 0.00012 21.9 0.1 1.6 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.25 EER23442.1 - 3.5e-59 200.3 0.0 4.8e-59 199.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23442.1 - 1.5e-27 96.5 0.0 2.2e-27 96.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER23442.1 - 3.1e-09 36.6 0.0 4.2e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EER23442.1 - 0.015 14.6 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER23442.1 - 0.16 11.9 0.0 0.55 10.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.26 EER23443.1 - 2e-50 170.1 0.0 2.5e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER23443.1 - 0.00041 20.1 0.0 0.00069 19.3 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EER23443.1 - 0.0024 18.1 0.0 0.0036 17.6 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 EER23443.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 UEV domain Nucleos_tra2_C PF07662.13 EER23444.1 - 1.8e-71 240.3 1.6 1.8e-71 240.3 1.6 3.3 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EER23444.1 - 1.1e-22 80.4 3.9 1.1e-22 80.4 3.9 2.3 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus AMP-binding PF00501.28 EER23445.1 - 1.1e-69 235.0 0.0 1.3e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER23445.1 - 3e-19 69.8 0.7 7.7e-19 68.5 0.7 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain A_deaminase PF00962.22 EER23446.1 - 1.5e-22 80.3 0.0 2.8e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase LRRNT_2 PF08263.12 EER23446.1 - 0.072 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain ATG2_CAD PF13329.6 EER23447.1 - 3.7e-45 153.4 0.1 1.3e-44 151.7 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EER23447.1 - 2.1e-30 104.9 0.1 2e-29 101.7 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13 PF16908.5 EER23447.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 2 0 0 2 2 2 0 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EER23447.1 - 0.034 13.9 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal Lipase_GDSL_2 PF13472.6 EER23448.1 - 2.2e-10 41.2 0.0 2.9e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EER23448.1 - 1.3e-06 28.6 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4594 PF15266.6 EER23450.1 - 9.2 6.6 7.5 7.1 6.9 3.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4594) adh_short PF00106.25 EER23451.1 - 1.4e-05 24.7 0.1 0.00055 19.4 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER23451.1 - 0.0047 16.5 0.1 0.013 15.1 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.12 EER23451.1 - 0.056 12.6 0.0 0.087 12.0 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein CN_hydrolase PF00795.22 EER23452.1 - 1.6e-58 198.1 0.0 1.8e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Kelch_4 PF13418.6 EER23452.1 - 0.089 12.8 0.0 16 5.6 0.0 2.7 2 1 0 2 2 2 0 Galactose oxidase, central domain Ribosomal_L31e PF01198.19 EER23453.1 - 1.3e-40 137.5 0.5 1.6e-40 137.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ran_BP1 PF00638.18 EER23454.1 - 1.3e-11 44.8 0.0 2.3e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 EER23454.1 - 8.7e-07 29.5 0.8 8.7e-07 29.5 0.8 5.2 5 1 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) SCP2 PF02036.17 EER23455.1 - 2e-25 89.2 0.2 2.4e-25 88.9 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EER23455.1 - 1.2e-05 25.6 0.1 1.6e-05 25.2 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 EER23455.1 - 0.0016 18.8 0.0 0.0022 18.4 0.0 1.3 1 1 0 1 1 1 1 Sterol carrier protein domain Ribosomal_L2_C PF03947.18 EER23457.1 - 8.8e-52 174.6 0.4 3.6e-51 172.6 0.4 2.1 1 1 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EER23457.1 - 5.1e-25 87.2 0.7 1e-24 86.3 0.7 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain HNH_2 PF13391.6 EER23459.1 - 1.2e-19 70.2 0.0 2.9e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Cyclin_N PF00134.23 EER23460.1 - 7.2e-44 148.6 0.1 2.1e-43 147.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EER23460.1 - 2.3e-31 108.3 0.1 4.6e-31 107.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.23 EER23462.1 - 7.4e-11 42.7 0.1 3e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EER23462.1 - 0.0049 17.3 0.0 0.01 16.3 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EER23462.1 - 0.012 15.5 0.0 0.056 13.3 0.0 1.9 2 0 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.18 EER23463.1 - 1.1e-07 31.7 0.1 1.7e-05 24.6 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EER23463.1 - 2e-05 24.0 0.0 3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.15 EER23463.1 - 0.16 11.6 0.5 0.42 10.2 0.2 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF2985 PF11204.8 EER23464.1 - 3.4e-22 78.4 3.5 5.8e-22 77.6 3.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SIR2 PF02146.17 EER23465.1 - 2.6e-57 193.6 0.0 4e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EER23465.1 - 1.2e-05 25.1 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EER23465.1 - 0.00093 19.0 0.0 1.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPR_2 PF07719.17 EER23466.1 - 8e-14 50.6 0.1 9.6e-05 22.2 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EER23466.1 - 2.8e-11 43.3 6.5 0.0062 17.3 0.0 5.4 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EER23466.1 - 3.6e-11 43.2 0.0 1.6e-06 28.3 0.0 3.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EER23466.1 - 5.2e-10 38.7 0.0 7.3e-05 22.7 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EER23466.1 - 1.1e-09 38.6 1.3 0.0082 16.6 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EER23466.1 - 2.5e-09 36.5 0.0 0.0011 18.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EER23466.1 - 6.1e-07 30.0 1.3 0.17 12.6 0.0 4.2 3 2 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER23466.1 - 2.3e-06 27.2 0.6 0.032 14.2 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 EER23466.1 - 5.8e-06 26.4 2.7 0.027 15.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EER23466.1 - 5.1e-05 22.8 0.4 0.024 14.0 0.0 2.8 1 1 0 2 2 2 2 MalT-like TPR region TPR_11 PF13414.6 EER23466.1 - 5.5e-05 22.8 0.3 0.0012 18.5 0.0 3.0 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 EER23466.1 - 0.00011 22.5 0.9 8.8 7.2 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EER23466.1 - 0.00064 19.5 6.1 4.2 7.4 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EER23466.1 - 0.0013 18.9 0.0 4.7 7.5 0.0 3.4 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4953 PF16313.5 EER23466.1 - 0.0017 17.6 0.9 0.21 10.8 0.0 2.2 2 0 0 2 2 2 2 Met-zincin TPR_9 PF13371.6 EER23466.1 - 0.015 15.4 10.6 0.9 9.7 0.2 5.0 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EER23466.1 - 0.021 15.2 0.0 40 4.9 0.0 4.9 6 0 0 6 6 5 0 Tetratricopeptide repeat RWD PF05773.22 EER23467.1 - 2.1e-25 89.3 0.4 2.1e-25 89.3 0.4 1.7 2 0 0 2 2 2 1 RWD domain AAA_23 PF13476.6 EER23467.1 - 0.015 15.8 5.6 0.019 15.4 5.6 1.4 1 0 0 1 1 1 0 AAA domain GAGA_bind PF06217.12 EER23467.1 - 0.078 13.3 2.4 0.096 13.0 2.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family U79_P34 PF03064.16 EER23467.1 - 0.18 11.2 6.3 0.28 10.5 6.3 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 MPM1 PF17234.2 EER23467.1 - 2.7 8.2 10.2 1.5 9.1 7.5 1.7 1 1 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DFRP_C PF16543.5 EER23467.1 - 4.1 7.9 19.7 1.2 9.7 15.0 2.5 2 1 0 2 2 2 0 DRG Family Regulatory Proteins, Tma46 Complex1_LYR PF05347.15 EER23468.1 - 7.1e-11 42.0 0.9 1.1e-10 41.3 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) UQ_con PF00179.26 EER23469.1 - 9.6e-17 60.9 0.0 1e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EER23469.1 - 0.12 12.7 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain DCB PF16213.5 EER23470.1 - 4.5e-43 147.0 1.5 1.1e-41 142.5 2.2 2.6 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EER23470.1 - 6.4e-41 139.9 2.1 6.4e-41 139.9 2.1 4.5 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EER23470.1 - 4.4e-20 71.5 2.0 8.7e-20 70.5 2.0 1.5 1 0 0 1 1 1 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 EER23470.1 - 0.00024 20.9 1.3 0.028 14.3 0.0 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.8 EER23470.1 - 0.001 19.6 8.3 0.019 15.6 0.1 4.8 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 EER23470.1 - 0.053 13.8 0.1 9.9 6.7 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat MFS_1 PF07690.16 EER23471.1 - 4.2e-28 98.3 29.7 4.2e-28 98.3 29.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF5367 PF17329.2 EER23471.1 - 1.8 8.7 7.4 15 5.8 0.8 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5367) Vps26 PF03643.15 EER23472.1 - 3.2e-123 410.1 0.7 7.7e-122 405.6 0.7 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EER23472.1 - 0.0018 18.3 0.1 0.55 10.3 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EER23472.1 - 0.043 14.3 0.1 0.3 11.5 0.0 2.3 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain IL17R_D_N PF16742.5 EER23472.1 - 0.075 13.1 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D AAA_33 PF13671.6 EER23473.1 - 6.1e-13 49.1 0.0 8.8e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EER23473.1 - 1.2e-11 45.2 0.0 2.8e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 EER23473.1 - 1.9e-11 44.4 0.0 2.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.6 EER23473.1 - 2.4e-07 31.2 0.0 5.2e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EER23473.1 - 7.3e-06 25.9 0.1 2.4e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase dNK PF01712.19 EER23473.1 - 1.4e-05 25.0 0.6 0.098 12.5 0.3 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_28 PF13521.6 EER23473.1 - 0.00012 22.4 0.0 0.00021 21.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EER23473.1 - 0.00022 21.7 0.1 0.00028 21.3 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EER23473.1 - 0.00026 21.0 0.0 0.00058 19.8 0.0 1.5 2 0 0 2 2 1 1 Rad17 P-loop domain APS_kinase PF01583.20 EER23473.1 - 0.00041 20.3 0.0 0.00059 19.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 EER23473.1 - 0.00081 18.7 0.1 0.0044 16.3 0.1 2.0 1 1 0 1 1 1 1 Zeta toxin TsaE PF02367.17 EER23473.1 - 0.0013 18.8 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EER23473.1 - 0.0021 18.3 0.1 0.0036 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EER23473.1 - 0.0027 18.1 0.0 0.0057 17.1 0.0 1.6 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.12 EER23473.1 - 0.0054 16.7 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EER23473.1 - 0.0061 16.3 0.1 0.01 15.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EER23473.1 - 0.0098 15.9 0.0 0.049 13.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain CoaE PF01121.20 EER23473.1 - 0.015 14.9 0.1 0.034 13.8 0.0 1.6 2 0 0 2 2 1 0 Dephospho-CoA kinase PRK PF00485.18 EER23473.1 - 0.02 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 EER23473.1 - 0.022 15.1 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase tRNA_lig_kinase PF08303.11 EER23473.1 - 0.022 14.8 0.0 0.097 12.8 0.0 1.9 2 0 0 2 2 2 0 tRNA ligase kinase domain Mg_chelatase PF01078.21 EER23473.1 - 0.034 13.5 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 EER23473.1 - 0.049 13.8 0.1 0.16 12.1 0.0 1.8 1 1 1 2 2 2 0 Cytidylate kinase-like family AAA_5 PF07728.14 EER23473.1 - 0.052 13.6 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ADK PF00406.22 EER23473.1 - 0.055 13.6 0.1 0.87 9.7 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase T2SSE PF00437.20 EER23473.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 EER23473.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IPT PF01745.16 EER23473.1 - 0.074 12.4 0.1 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Isopentenyl transferase ABC_tran PF00005.27 EER23473.1 - 0.079 13.5 0.2 0.13 12.8 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EER23473.1 - 0.08 12.5 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EER23473.1 - 0.1 12.2 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EER23473.1 - 0.1 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain VirE PF05272.11 EER23473.1 - 0.13 12.0 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E AAA_29 PF13555.6 EER23473.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EER23473.1 - 0.19 11.7 0.2 0.56 10.1 0.0 1.8 2 0 0 2 2 2 0 NTPase 2-oxoacid_dh PF00198.23 EER23474.1 - 1e-78 264.0 0.3 1.4e-78 263.6 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EER23474.1 - 1.1e-14 54.5 0.1 2.8e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 EER23474.1 - 4.1e-13 48.9 0.5 1.1e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme PI-PLC-X PF00388.19 EER23475.1 - 5.6e-10 39.0 0.0 1.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.20 EER23476.1 - 0.0062 16.7 0.1 0.23 11.6 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein L10 SMG1 PF15785.5 EER23476.1 - 0.15 10.4 0.1 0.19 10.0 0.1 1.1 1 0 0 1 1 1 0 Serine/threonine-protein kinase smg-1 Glycos_transf_3 PF00591.21 EER23477.1 - 2.4e-56 191.2 0.0 1.4e-45 155.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EER23477.1 - 8.9e-07 28.7 0.2 1.6e-06 27.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.13 EER23478.1 - 2.2e-16 59.2 7.4 2.9e-16 58.8 7.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2318 PF10080.9 EER23478.1 - 0.004 17.2 0.4 0.0046 17.0 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) TFIIS_C PF01096.18 EER23478.1 - 0.0057 16.5 0.8 3.2 7.7 0.0 2.4 2 1 0 2 2 2 2 Transcription factor S-II (TFIIS) HypA PF01155.19 EER23478.1 - 0.011 15.8 0.3 0.012 15.6 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EER23478.1 - 0.013 15.6 0.3 0.018 15.0 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EER23478.1 - 0.018 15.2 0.9 0.031 14.4 0.9 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zf_UBZ PF18439.1 EER23478.1 - 0.033 13.8 1.5 1.8 8.2 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2197 PF09963.9 EER23478.1 - 0.038 14.3 2.3 1.7 9.0 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) A2L_zn_ribbon PF08792.10 EER23478.1 - 0.044 13.5 1.1 2.8 7.7 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zinc-ribbons_6 PF07191.12 EER23478.1 - 0.044 13.8 0.9 0.065 13.2 0.9 1.3 1 0 0 1 1 1 0 zinc-ribbons Zn_ribbon_recom PF13408.6 EER23478.1 - 0.048 14.2 5.1 2.4 8.8 1.3 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_13 PF09855.9 EER23478.1 - 0.067 13.4 0.1 0.067 13.4 0.1 1.7 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF3268 PF11672.8 EER23478.1 - 0.087 13.2 1.3 0.46 10.8 1.3 1.9 1 1 0 1 1 1 0 zinc-finger-containing domain Rubredoxin_2 PF18073.1 EER23478.1 - 0.48 10.2 3.3 5.3 6.9 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Fe_hyd_lg_C PF02906.14 EER23480.1 - 3.3e-50 171.0 0.0 6.5e-50 170.1 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.9 EER23481.1 - 5.8e-18 65.7 0.0 1.8e-17 64.0 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 EER23481.1 - 0.19 11.8 0.0 0.36 10.9 0.0 1.5 1 0 0 1 1 1 0 Macro domain Fapy_DNA_glyco PF01149.24 EER23482.1 - 1.9e-33 115.6 0.0 4.5e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EER23482.1 - 1.6e-19 69.7 0.0 3.1e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EER23482.1 - 0.0018 17.1 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Cid2 PF09774.9 EER23483.1 - 4.1e-56 189.8 0.2 4.9e-56 189.6 0.2 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 EER23484.1 - 6.6e-216 718.2 12.2 2e-214 713.3 8.0 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EER23484.1 - 4e-22 76.5 24.0 2.1e-06 27.4 1.1 10.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EER23484.1 - 4.7e-21 75.1 22.0 0.00086 19.8 2.8 7.4 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EER23484.1 - 3.7e-20 70.9 15.2 0.00089 19.9 0.9 9.0 7 3 3 10 10 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EER23484.1 - 2e-14 53.9 14.4 4e-05 24.2 2.1 7.6 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EER23484.1 - 1.7e-12 46.6 26.9 2.5e-05 23.9 1.3 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 EER23484.1 - 5.6e-11 42.4 11.7 0.02 15.0 0.3 7.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER23484.1 - 8.2e-10 38.1 26.6 0.00022 21.2 0.6 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EER23484.1 - 1.9e-09 37.6 15.9 0.00093 19.4 3.7 5.5 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EER23484.1 - 2e-09 36.9 20.0 0.00027 20.5 0.7 5.9 7 0 0 7 7 6 3 TPR repeat TPR_17 PF13431.6 EER23484.1 - 1.8e-08 34.2 13.4 1.3 9.6 0.1 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EER23484.1 - 5.2e-07 29.9 18.5 0.24 11.7 0.4 7.4 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 EER23484.1 - 2.2e-06 27.1 10.7 0.0016 17.7 0.9 3.9 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EER23484.1 - 3.3e-06 27.4 15.2 0.2 12.4 0.1 7.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_3 PF07720.12 EER23484.1 - 4.9e-05 23.2 1.7 0.15 12.1 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 EER23484.1 - 7.3e-05 22.6 0.5 7.3e-05 22.6 0.5 3.9 4 1 1 5 5 4 1 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 EER23484.1 - 7.4e-05 22.3 4.1 0.28 10.5 3.7 3.8 2 1 0 2 2 2 1 MalT-like TPR region BTAD PF03704.17 EER23484.1 - 0.00019 21.9 5.9 0.001 19.6 0.1 3.6 4 1 0 4 4 3 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 EER23484.1 - 0.00047 20.0 10.2 1.2 9.3 0.1 5.8 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 EER23484.1 - 0.01 16.3 1.9 9.7 7.2 0.4 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EER23484.1 - 0.019 15.1 9.6 6.9 6.8 0.1 5.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EER23484.1 - 0.031 14.2 12.4 4.6 7.2 0.0 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EER23484.1 - 0.14 11.8 2.5 4.9 6.8 0.0 3.6 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_5 PF12688.7 EER23484.1 - 0.14 12.4 0.8 9.6 6.5 0.0 3.0 3 0 0 3 3 2 0 Tetratrico peptide repeat Rapsyn_N PF10579.9 EER23484.1 - 0.22 11.7 1.1 0.83 9.8 0.2 2.5 2 1 0 2 2 1 0 Rapsyn N-terminal myristoylation and linker region Prefoldin PF02996.17 EER23484.1 - 3.9 7.4 10.6 10 6.0 0.0 4.2 4 0 0 4 4 3 0 Prefoldin subunit TPR_20 PF14561.6 EER23484.1 - 5.9 7.3 11.2 5.1 7.5 0.4 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat zf-RING_2 PF13639.6 EER23486.1 - 8.5e-13 48.4 5.2 1.4e-12 47.7 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER23486.1 - 6.1e-11 42.0 5.5 1.1e-10 41.1 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EER23486.1 - 2.9e-09 36.5 2.7 2.9e-09 36.5 2.7 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EER23486.1 - 2.2e-08 33.8 4.3 3.7e-08 33.1 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EER23486.1 - 1.9e-07 31.2 7.7 4e-07 30.2 6.4 2.1 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EER23486.1 - 5.1e-07 29.6 3.5 8.2e-07 28.9 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EER23486.1 - 4.4e-06 26.6 1.4 2e-05 24.5 0.3 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EER23486.1 - 4e-05 23.4 3.5 6.2e-05 22.8 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EER23486.1 - 0.00014 21.4 3.2 0.00023 20.7 3.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EER23486.1 - 0.00049 20.1 3.9 0.0018 18.3 3.9 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 EER23486.1 - 0.001 18.9 3.9 0.0019 18.1 3.9 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_4 PF14447.6 EER23486.1 - 0.0015 18.3 3.0 0.0036 17.1 3.0 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EER23486.1 - 0.0026 17.5 1.4 0.0044 16.8 1.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EER23486.1 - 0.0032 17.6 5.0 0.0055 16.8 5.0 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_6 PF14835.6 EER23486.1 - 0.0064 16.3 1.6 0.01 15.7 1.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EER23486.1 - 0.011 15.9 2.0 0.026 14.7 2.0 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EER23486.1 - 0.016 15.5 4.0 0.029 14.7 4.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-Di19 PF05605.12 EER23486.1 - 0.032 14.5 1.8 1.2 9.5 0.2 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3H2C3 PF17122.5 EER23486.1 - 0.038 14.0 4.5 0.12 12.4 4.5 1.9 1 1 0 1 1 1 0 Zinc-finger Vps39_2 PF10367.9 EER23486.1 - 0.13 12.8 1.9 0.16 12.4 0.1 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 FANCL_C PF11793.8 EER23486.1 - 0.27 11.5 6.4 1.9 8.7 6.4 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EER23486.1 - 0.33 10.8 3.6 0.61 9.9 3.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Inhibitor_I53 PF11714.8 EER23487.1 - 0.0058 16.8 0.2 0.011 15.9 0.2 1.4 1 0 0 1 1 1 1 Thrombin inhibitor Madanin LRR_4 PF12799.7 EER23488.1 - 2.4e-06 27.7 9.1 0.23 11.9 0.1 4.9 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EER23488.1 - 0.0019 18.4 1.3 67 4.6 0.1 6.2 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 EER23488.1 - 0.0021 17.9 8.5 4.8 7.5 0.4 5.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_8 PF13855.6 EER23488.1 - 0.091 12.5 8.6 1.8 8.4 0.3 4.2 4 0 0 4 4 4 0 Leucine rich repeat FSA_C PF10479.9 EER23489.1 - 0.37 8.9 11.9 0.39 8.8 11.9 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SOG2 PF10428.9 EER23489.1 - 5.2 6.1 18.2 5.3 6.1 18.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SUZ PF12752.7 EER23490.1 - 5e-05 24.0 11.2 5e-05 24.0 11.2 4.9 2 1 1 3 3 3 1 SUZ domain GST_N_3 PF13417.6 EER23491.1 - 3.3e-21 75.5 0.0 7.4e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EER23491.1 - 2.1e-16 59.9 0.0 5.5e-16 58.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EER23491.1 - 7.6e-08 32.6 0.0 2.3e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EER23491.1 - 1e-05 25.5 0.2 2.3e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EER23491.1 - 0.022 14.9 0.0 0.08 13.2 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EER23491.1 - 0.032 14.8 0.0 0.062 13.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EER23491.1 - 0.089 13.0 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin ATP_bind_1 PF03029.17 EER23493.1 - 1.8e-71 240.7 0.0 2.8e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EER23493.1 - 1.5e-05 24.1 0.0 0.011 14.7 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EER23493.1 - 2.9e-05 23.7 0.0 0.00074 19.1 0.0 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EER23493.1 - 0.00032 20.8 0.0 0.0022 18.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EER23493.1 - 0.00047 19.7 0.0 0.61 9.5 0.0 3.2 3 0 0 3 3 3 1 ADP-ribosylation factor family Roc PF08477.13 EER23493.1 - 0.0012 19.1 0.0 0.33 11.2 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EER23493.1 - 0.0014 18.5 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 EER23493.1 - 0.0018 18.0 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EER23493.1 - 0.0019 17.5 0.0 0.0047 16.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain FeoB_N PF02421.18 EER23493.1 - 0.0027 17.2 0.0 0.097 12.2 0.0 2.7 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_33 PF13671.6 EER23493.1 - 0.0056 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EER23493.1 - 0.0058 16.9 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EER23493.1 - 0.0063 16.2 0.0 0.078 12.6 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain cobW PF02492.19 EER23493.1 - 0.0085 15.7 0.0 1.3 8.5 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 EER23493.1 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family G-alpha PF00503.20 EER23493.1 - 0.01 15.1 0.1 0.37 9.9 0.0 2.6 3 0 0 3 3 3 1 G-protein alpha subunit RsgA_GTPase PF03193.16 EER23493.1 - 0.01 15.8 0.0 3.9 7.3 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 EER23493.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EER23493.1 - 0.013 16.0 1.1 2.6 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EER23493.1 - 0.018 14.8 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EER23493.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Ras PF00071.22 EER23493.1 - 0.023 14.3 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Ras family PduV-EutP PF10662.9 EER23493.1 - 0.049 13.4 0.0 0.93 9.2 0.0 2.7 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 EER23493.1 - 0.056 13.2 0.0 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SRPRB PF09439.10 EER23493.1 - 0.062 12.7 0.0 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Pox_A32 PF04665.12 EER23493.1 - 0.066 12.7 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Poxvirus A32 protein DUF87 PF01935.17 EER23493.1 - 0.086 12.9 0.3 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 EER23493.1 - 0.12 11.8 0.2 3 7.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 EER23493.1 - 0.12 13.0 0.4 0.34 11.4 0.0 2.1 2 1 0 2 2 1 0 AAA domain CDC45 PF02724.14 EER23493.1 - 2.6 6.2 8.3 36 2.5 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein CwfJ_C_1 PF04677.15 EER23494.1 - 2.2e-31 108.2 0.0 1.7e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EER23494.1 - 2.8e-30 105.1 0.1 2.8e-30 105.1 0.1 2.5 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 FumaraseC_C PF10415.9 EER23494.1 - 0.076 13.5 1.8 11 6.5 0.2 3.2 2 0 0 2 2 2 0 Fumarase C C-terminus 2-Hacid_dh_C PF02826.19 EER23495.1 - 3.1e-58 196.0 0.0 4.3e-58 195.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER23495.1 - 1.2e-13 50.9 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EER23495.1 - 0.0011 19.2 0.1 0.0017 18.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EER23495.1 - 0.074 12.6 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Zn_clus PF00172.18 EER23496.1 - 2.1e-08 34.1 10.3 4.2e-08 33.2 10.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.12 EER23497.1 - 1.4e-08 34.4 0.5 2.3e-08 33.7 0.5 1.4 1 0 0 1 1 1 1 U1 zinc finger ISG65-75 PF11727.8 EER23497.1 - 0.0076 15.5 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Invariant surface glycoprotein CAP_GLY PF01302.25 EER23498.1 - 1.5e-19 69.8 0.1 2.7e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EER23498.1 - 7.6e-12 45.3 11.0 0.057 13.9 0.0 4.9 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EER23498.1 - 2.4e-05 23.9 7.6 0.0032 17.0 0.4 3.9 1 1 1 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 EER23498.1 - 0.00026 20.8 13.9 0.99 9.6 0.2 6.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.6 EER23498.1 - 0.012 15.3 22.8 0.21 11.4 2.6 5.8 2 1 4 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 EER23498.1 - 0.13 12.9 13.6 1.3e+02 3.8 0.0 6.9 6 1 0 6 6 6 0 Leucine Rich Repeat SF3A2 PF16835.5 EER23499.1 - 5.5e-37 126.0 0.0 8.3e-37 125.5 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EER23499.1 - 1.1e-05 25.6 0.5 2.1e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EER23499.1 - 0.05 13.2 1.5 0.11 12.1 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 EER23500.1 - 7.9e-57 192.6 0.0 1.5e-55 188.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23500.1 - 1.3e-24 86.9 0.5 5.5e-19 68.5 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EER23500.1 - 4.8e-06 25.8 0.2 6.7e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EER23500.1 - 0.00038 20.5 1.1 0.04 13.8 0.2 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EER23500.1 - 0.0011 18.4 0.6 0.0022 17.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EER23500.1 - 0.0011 18.3 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NFACT-C PF11923.8 EER23500.1 - 0.023 14.6 0.3 0.047 13.6 0.3 1.5 1 0 0 1 1 1 0 NFACT protein C-terminal domain Seadorna_VP7 PF07387.11 EER23500.1 - 0.036 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EER23500.1 - 0.072 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PA28_alpha PF02251.18 EER23500.1 - 0.15 12.1 0.2 0.83 9.7 0.0 2.3 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit APH PF01636.23 EER23501.1 - 1.5e-15 57.8 0.0 2e-14 54.1 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EER23501.1 - 0.00098 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.11 EER23501.1 - 0.056 12.3 0.0 0.29 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Tim54 PF11711.8 EER23502.1 - 4.4e-148 493.1 0.0 5.1e-148 492.8 0.0 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 BUD22 PF09073.10 EER23502.1 - 0.0071 15.7 0.2 0.0071 15.7 0.2 2.0 2 0 0 2 2 2 1 BUD22 L31 PF09784.9 EER23502.1 - 0.07 13.6 0.2 0.42 11.1 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Pkinase PF00069.25 EER23503.1 - 9.6e-23 80.9 0.0 1.3e-21 77.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23503.1 - 8.6e-10 38.3 0.8 0.00019 20.8 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EER23503.1 - 0.015 14.6 0.0 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EER23503.1 - 0.07 13.0 1.3 0.15 12.0 0.4 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EER23503.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5122 PF17164.4 EER23503.1 - 0.18 12.1 0.0 0.42 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller BSD PF03909.17 EER23504.1 - 5.9e-28 96.7 8.1 4.5e-14 52.2 0.9 3.0 3 0 0 3 3 3 2 BSD domain PH_TFIIH PF08567.11 EER23504.1 - 6.7e-24 84.0 0.0 1.6e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain KfrA_N PF11740.8 EER23504.1 - 2.6 8.7 9.3 2.3 8.9 2.4 3.4 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term ING PF12998.7 EER23506.1 - 1.7e-10 41.3 0.0 3e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EER23506.1 - 3.1e-06 27.0 7.8 5e-06 26.3 7.8 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EER23506.1 - 0.12 12.6 2.7 0.29 11.4 2.6 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EER23506.1 - 0.18 11.4 2.5 0.32 10.6 2.5 1.4 1 0 0 1 1 1 0 PHD-finger Transket_pyr PF02779.24 EER23507.1 - 1.9e-64 216.6 0.0 3.3e-64 215.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EER23507.1 - 2.5e-58 196.1 0.0 5e-58 195.1 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EER23507.1 - 3.3e-57 193.7 0.0 4.8e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EER23507.1 - 1.9e-18 65.7 0.4 1.9e-18 65.7 0.4 1.7 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus Sld5 PF05916.11 EER23510.1 - 3.5e-19 69.3 0.0 4.3e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Cnn_1N PF07989.11 EER23511.1 - 2.1e-15 56.6 8.1 4e-15 55.7 8.1 1.4 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 FPP PF05911.11 EER23511.1 - 0.0019 16.5 1.3 0.0028 16.0 1.3 1.1 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil DUF3825 PF12873.7 EER23511.1 - 0.016 14.7 0.2 0.027 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) Prominin PF05478.11 EER23511.1 - 0.027 12.4 1.1 0.039 11.9 1.1 1.1 1 0 0 1 1 1 0 Prominin Atg14 PF10186.9 EER23511.1 - 0.05 12.7 1.1 0.085 11.9 1.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Nmad5 PF18757.1 EER23511.1 - 0.062 13.5 0.1 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 FlxA PF14282.6 EER23511.1 - 0.18 11.8 3.1 0.47 10.5 3.1 1.7 1 0 0 1 1 1 0 FlxA-like protein DivIC PF04977.15 EER23511.1 - 0.18 11.6 6.6 0.27 11.0 5.7 1.7 1 1 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 EER23511.1 - 0.18 12.2 6.2 0.37 11.2 6.2 1.5 1 0 0 1 1 1 0 Cell division protein ZapB CENP-H PF05837.12 EER23511.1 - 0.2 12.1 2.0 0.43 11.0 2.0 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FapA PF03961.13 EER23511.1 - 0.27 9.8 3.4 0.39 9.3 3.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HMMR_N PF15905.5 EER23511.1 - 0.35 10.3 5.5 0.74 9.2 5.5 1.5 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 EER23511.1 - 0.4 9.5 4.7 0.83 8.5 4.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 EER23511.1 - 0.83 9.7 6.4 1.6 8.8 6.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EER23511.1 - 0.88 9.6 2.2 1.9 8.6 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.11 EER23511.1 - 1.2 8.9 4.3 3.1 7.6 3.9 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 YabA PF06156.13 EER23511.1 - 2.6 8.7 7.1 5.5 7.7 5.9 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF5082 PF16888.5 EER23511.1 - 5.4 7.3 11.4 4.2 7.7 0.5 2.8 2 1 1 3 3 2 0 Domain of unknown function (DUF5082) Sod_Fe_C PF02777.18 EER23512.1 - 2.7e-37 127.0 0.2 2.7e-37 127.0 0.2 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EER23512.1 - 9.9e-30 102.9 1.2 1.6e-29 102.2 1.2 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.12 EER23513.1 - 5.8e-79 265.6 5.3 1e-78 264.8 5.3 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EER23513.1 - 3e-15 55.8 1.0 6.1e-15 54.8 1.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EER23513.1 - 7e-07 29.2 1.3 2.3e-06 27.6 1.3 1.9 1 0 0 1 1 1 1 G-patch domain ATP-synt_E PF05680.12 EER23513.1 - 9.3 6.7 12.4 0.52 10.7 0.4 2.7 2 0 0 2 2 2 0 ATP synthase E chain VPS13_mid_rpt PF16910.5 EER23514.1 - 2.5e-96 321.7 7.9 2.1e-90 302.3 0.1 5.3 5 0 0 5 5 5 2 Repeating coiled region of VPS13 SHR-BD PF06650.12 EER23514.1 - 1.4e-94 316.5 0.0 2.2e-93 312.6 0.0 2.9 4 0 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 EER23514.1 - 1.2e-81 274.0 0.5 1.9e-80 270.1 0.0 3.2 4 0 0 4 4 4 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EER23514.1 - 4.2e-73 244.9 1.4 2.5e-68 229.3 0.2 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EER23514.1 - 2.5e-42 143.7 0.1 1.3e-41 141.4 0.1 2.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EER23514.1 - 8.8e-07 29.2 0.0 3e-06 27.5 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain ATG22 PF11700.8 EER23515.1 - 2.8e-121 405.5 22.1 3.2e-121 405.3 22.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Cytochrom_B558a PF05038.13 EER23515.1 - 0.77 9.3 3.3 0.43 10.1 0.4 2.0 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DUF3429 PF11911.8 EER23516.1 - 1.3e-44 152.0 12.1 1.9e-44 151.4 12.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.16 EER23517.1 - 7.2e-71 238.0 0.3 1.3e-70 237.2 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EER23517.1 - 1.3e-64 218.1 0.0 1.9e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EER23517.1 - 0.00029 20.4 0.2 0.045 13.3 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.18 EER23518.1 - 9.7e-57 191.9 0.5 2e-56 190.9 0.5 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EER23518.1 - 1.2e-42 145.4 0.0 3.5e-42 144.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER23518.1 - 1.6e-09 37.4 0.6 6.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EER23518.1 - 1.8e-05 24.8 0.0 5.9e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EER23518.1 - 2.6e-05 24.7 0.5 0.00032 21.1 0.5 2.6 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EER23518.1 - 0.00011 21.5 1.1 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 EER23518.1 - 0.00072 19.8 3.6 0.025 14.8 0.3 3.3 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EER23518.1 - 0.00076 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EER23518.1 - 0.0046 17.1 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EER23518.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EER23518.1 - 0.02 15.0 0.0 0.061 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EER23518.1 - 0.022 14.4 1.5 0.67 9.5 0.3 2.4 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EER23518.1 - 0.025 15.1 0.0 0.083 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EER23518.1 - 0.026 13.9 0.2 0.05 13.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EER23518.1 - 0.037 13.2 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 EER23518.1 - 0.066 13.4 0.3 0.21 11.8 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EER23518.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EER23518.1 - 0.16 11.9 2.8 1.9 8.4 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_7 PF12775.7 EER23518.1 - 0.17 11.4 0.4 0.45 10.0 0.1 1.9 2 1 0 2 2 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EER23518.1 - 0.17 11.1 1.7 0.89 8.8 0.5 2.4 1 1 1 2 2 2 0 Zeta toxin NTP_transferase PF00483.23 EER23520.1 - 2.1e-52 178.2 0.0 4e-52 177.3 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EER23520.1 - 9.5e-15 53.7 8.3 1.6e-10 40.3 1.9 3.7 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EER23520.1 - 4.4e-09 36.9 0.0 5.9e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EER23520.1 - 2.3e-06 27.2 0.5 2.3e-06 27.2 0.5 3.4 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EER23520.1 - 0.0067 14.6 0.1 0.01 14.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 EER23520.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.25 EER23521.1 - 3.4e-09 36.4 0.0 0.00016 21.2 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EER23521.1 - 0.0038 16.8 0.0 2.8 7.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER23521.1 - 0.031 14.2 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 KR domain zf-H2C2_2 PF13465.6 EER23522.1 - 2.8e-15 55.9 28.5 1.4e-06 28.5 0.4 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 EER23522.1 - 2.6e-14 52.7 32.9 2.1e-05 24.7 2.2 4.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER23522.1 - 2.6e-05 24.7 26.9 0.035 15.0 2.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 EER23522.1 - 0.00047 20.7 15.5 0.75 10.5 0.1 4.3 2 1 2 4 4 4 3 FOXP coiled-coil domain ATXN-1_C PF12547.8 EER23522.1 - 0.059 13.7 3.2 0.14 12.5 3.2 1.7 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator Suc_Fer-like PF06999.12 EER23523.1 - 2.5e-71 239.6 0.0 3.1e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like 2-Hacid_dh_C PF02826.19 EER23524.1 - 1.6e-42 144.9 0.0 2.7e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER23524.1 - 8.1e-08 32.0 0.0 1.4e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PH_10 PF15411.6 EER23526.1 - 4.9e-42 143.1 0.0 1e-41 142.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EER23526.1 - 2e-34 117.7 0.0 4.3e-34 116.6 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 EER23526.1 - 5.8e-26 91.8 1.6 1.1e-25 91.0 1.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EER23526.1 - 7.1e-08 32.3 0.1 2.4e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 PB1 domain YppF PF14178.6 EER23526.1 - 0.3 11.0 1.1 6.9 6.6 0.4 3.3 3 0 0 3 3 3 0 YppF-like protein WD40 PF00400.32 EER23527.1 - 1.9e-30 104.4 12.9 1.1e-05 26.1 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 EER23527.1 - 2.5e-13 49.7 0.7 5.7e-13 48.5 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER23527.1 - 2.8e-08 33.4 0.1 6e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 EER23527.1 - 0.001 17.8 0.5 2.2 6.8 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 F-box_4 PF15966.5 EER23527.1 - 0.012 15.5 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 F-box MgtE_N PF03448.17 EER23527.1 - 0.039 14.6 0.1 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 MgtE intracellular N domain Uds1 PF15456.6 EER23529.1 - 2.9e-40 137.4 6.0 2.9e-40 137.4 6.0 5.8 3 1 3 6 6 6 1 Up-regulated During Septation TMF_TATA_bd PF12325.8 EER23529.1 - 0.0042 17.3 4.9 0.0042 17.3 4.9 7.9 5 2 2 8 8 8 1 TATA element modulatory factor 1 TATA binding PMC2NT PF08066.12 EER23529.1 - 0.95 10.2 7.2 4.3 8.1 0.8 4.2 3 0 0 3 3 3 0 PMC2NT (NUC016) domain DUF4407 PF14362.6 EER23529.1 - 3.6 6.9 63.0 0.36 10.1 5.4 3.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DUF2935 PF11155.8 EER23529.1 - 6.9 7.0 13.4 0.36 11.2 1.3 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF2935) MFS_1 PF07690.16 EER23530.1 - 9.5e-22 77.4 27.5 1.6e-21 76.6 27.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EER23530.1 - 0.34 9.7 9.5 0.67 8.8 0.3 2.9 1 1 2 3 3 3 0 MFS_1 like family UCR_hinge PF02320.16 EER23531.1 - 3.9e-26 91.0 7.8 8.3e-26 90.0 7.8 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF4211 PF13926.6 EER23531.1 - 0.045 13.8 2.5 0.075 13.1 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Ribosomal_60s PF00428.19 EER23531.1 - 0.052 14.1 15.9 0.1 13.2 15.9 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3391 PF11871.8 EER23531.1 - 1.5 9.3 7.8 0.13 12.8 2.3 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3391) Pox_Ag35 PF03286.14 EER23531.1 - 8.8 6.1 6.9 17 5.1 6.9 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM180 PF15173.6 EER23532.1 - 0.015 15.3 0.5 0.029 14.4 0.5 1.4 1 0 0 1 1 1 0 FAM180 family Tmemb_cc2 PF10267.9 EER23532.1 - 0.22 10.6 9.6 0.21 10.7 7.7 1.8 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Csm1_N PF18504.1 EER23532.1 - 0.63 10.4 7.2 1.1 9.7 4.0 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain GPS2_interact PF15784.5 EER23532.1 - 1.2 9.6 7.2 2.6 8.5 5.2 2.5 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Exonuc_VII_L PF02601.15 EER23532.1 - 1.5 8.3 5.5 2.7 7.5 5.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Phage_GP20 PF06810.11 EER23532.1 - 1.8 8.3 5.2 0.77 9.6 2.1 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 Acyltransferase PF01553.21 EER23533.1 - 1.1e-09 38.1 0.0 0.0017 18.0 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase DUF4220 PF13968.6 EER23533.1 - 0.43 9.9 3.4 0.71 9.2 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Prenyltransf PF01255.19 EER23534.1 - 1.4e-81 273.3 0.0 2.2e-81 272.7 0.0 1.3 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Sacchrp_dh_C PF16653.5 EER23535.1 - 2.2e-95 319.8 0.0 3.8e-95 319.0 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EER23535.1 - 4.3e-26 91.7 0.2 6.5e-26 91.1 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EER23535.1 - 8.5e-07 29.1 0.0 1.9e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EER23535.1 - 0.00036 20.5 0.0 0.00065 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_7 PF13241.6 EER23535.1 - 0.083 13.3 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.6 EER23536.1 - 2.5e-21 77.1 0.0 5.9e-21 75.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EER23536.1 - 5.3e-12 45.9 0.0 8.2e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_15 PF00723.21 EER23537.1 - 5.8e-100 335.2 0.0 6.9e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EER23537.1 - 3.4e-32 110.2 0.0 6.9e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Aha1_N PF09229.11 EER23538.1 - 2e-42 144.6 1.8 3.2e-42 144.0 0.6 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EER23538.1 - 2.4e-18 66.6 0.4 4.3e-18 65.7 0.4 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Drc1-Sld2 PF11719.8 EER23538.1 - 0.083 12.4 2.2 0.11 12.0 2.2 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein Mucin PF01456.17 EER23538.1 - 1.3 9.1 9.0 2.2 8.3 9.0 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein FBPase PF00316.20 EER23540.1 - 5.9e-67 224.8 0.1 7.7e-67 224.4 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain adh_short_C2 PF13561.6 EER23541.1 - 5.1e-54 183.3 0.0 5.8e-54 183.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER23541.1 - 9.3e-47 159.0 0.1 1.4e-46 158.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER23541.1 - 1.4e-09 38.1 0.2 2.3e-09 37.4 0.2 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EER23541.1 - 1.2e-05 24.9 0.1 2.1e-05 24.1 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EER23541.1 - 0.00082 18.7 0.3 0.0081 15.5 0.1 2.4 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_transf_5 PF08323.11 EER23541.1 - 0.043 13.5 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 Starch synthase catalytic domain DUF1815 PF08844.10 EER23541.1 - 0.055 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) DeoC PF01791.9 EER23541.1 - 0.056 13.1 0.1 0.081 12.5 0.1 1.2 1 0 0 1 1 1 0 DeoC/LacD family aldolase RmlD_sub_bind PF04321.17 EER23541.1 - 0.063 12.4 0.1 0.38 9.8 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain V_ATPase_I PF01496.19 EER23542.1 - 0 1074.7 0.0 0 1074.5 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MAD PF05557.13 EER23542.1 - 0.12 10.7 4.9 0.09 11.1 0.3 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein CheZ PF04344.13 EER23542.1 - 0.18 11.7 0.7 0.73 9.7 0.1 2.1 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ Nup54 PF13874.6 EER23542.1 - 0.47 10.6 2.1 1.1 9.4 0.3 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 YtpI PF14007.6 EER23542.1 - 0.48 10.6 4.5 4.3 7.5 0.9 2.8 2 0 0 2 2 2 0 YtpI-like protein Filament PF00038.21 EER23542.1 - 0.54 9.8 4.0 8.9 5.8 0.6 2.2 2 0 0 2 2 2 0 Intermediate filament protein DUF1218 PF06749.12 EER23542.1 - 1.3 9.6 5.7 1.1 9.8 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) MOSC PF03473.17 EER23543.1 - 2.2e-06 27.7 0.0 6.9e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 MOSC domain BLM10_mid PF16507.5 EER23544.1 - 3.1e-209 696.0 0.0 4.9e-209 695.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EER23544.1 - 4.8e-28 96.9 0.0 3e-27 94.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EER23544.1 - 1.3e-24 86.3 0.1 4.2e-24 84.6 0.1 1.9 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 EER23544.1 - 0.026 14.7 3.9 3 8.3 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat CLASP_N PF12348.8 EER23544.1 - 0.032 13.8 0.4 5.5 6.5 0.0 2.7 2 0 0 2 2 2 0 CLASP N terminal HEAT_2 PF13646.6 EER23544.1 - 0.085 13.3 0.1 9.4 6.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 EER23544.1 - 0.12 12.9 0.0 7.4 7.2 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Mannosyl_trans2 PF04188.13 EER23545.1 - 4.5e-52 177.9 12.7 5.6e-52 177.5 12.7 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Pro_CA PF00484.19 EER23547.1 - 1.8e-43 148.5 0.0 2.8e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase FeS PF04060.13 EER23547.1 - 0.062 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 Putative Fe-S cluster GFO_IDH_MocA PF01408.22 EER23548.1 - 1.8e-15 57.8 0.0 3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AbiEii PF08843.11 EER23549.1 - 0.01 15.8 0.0 0.086 12.8 0.0 1.9 1 1 0 2 2 2 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Thiolase_N PF00108.23 EER23551.1 - 6.9e-74 248.5 5.2 6.9e-74 248.5 5.2 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EER23551.1 - 8.9e-45 151.3 0.3 1.9e-44 150.2 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 EER23551.1 - 0.0014 18.8 0.0 0.0053 16.9 0.0 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal RraA-like PF03737.15 EER23552.1 - 1.6e-27 96.5 0.1 2.3e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 Aldolase/RraA Borrelia_P83 PF05262.11 EER23553.1 - 6.3 5.2 35.8 14 4.0 35.8 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein Velvet PF11754.8 EER23554.1 - 7e-49 167.0 4.9 2e-33 116.4 0.2 2.4 2 1 1 3 3 3 2 Velvet factor MOZ_SAS PF01853.18 EER23555.1 - 3e-74 248.6 0.0 4.7e-74 247.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EER23555.1 - 3.4e-20 71.4 3.1 7.7e-20 70.3 3.1 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain PHD_4 PF16866.5 EER23555.1 - 4.5e-10 39.5 15.5 1.3e-09 38.0 15.5 1.8 1 0 0 1 1 1 1 PHD-finger PARM PF17061.5 EER23555.1 - 0.03 14.5 3.0 0.087 13.0 3.0 1.7 1 0 0 1 1 1 0 PARM PHD PF00628.29 EER23555.1 - 0.24 11.3 20.2 0.075 12.9 16.2 2.2 2 0 0 2 2 2 0 PHD-finger zf-MIZ PF02891.20 EER23555.1 - 2.5 7.9 8.0 6.4 6.6 8.0 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger MWFE PF15879.5 EER23556.1 - 3.6e-28 97.5 0.3 4.3e-28 97.2 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit DNA_pol_lambd_f PF10391.9 EER23556.1 - 0.13 12.1 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Acetyltransf_2 PF00797.17 EER23557.1 - 3.8e-39 134.9 0.0 4.7e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase YTH PF04146.15 EER23559.1 - 1e-34 119.9 1.4 6.6e-34 117.3 0.2 2.6 2 1 0 2 2 2 1 YT521-B-like domain Drf_GBD PF06371.13 EER23560.1 - 6.5e-18 65.0 2.7 1.1e-15 57.7 2.7 2.6 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EER23560.1 - 0.005 16.5 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Diaphanous FH3 Domain Nramp PF01566.18 EER23561.1 - 2.4e-89 299.8 19.0 2.4e-89 299.8 19.0 1.7 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Snf7 PF03357.21 EER23562.1 - 3.6e-41 140.6 13.0 4.5e-41 140.3 13.0 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.6 EER23562.1 - 0.0017 18.1 5.7 0.0017 18.1 5.7 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) Zwint PF15556.6 EER23562.1 - 0.0028 17.2 5.6 0.0041 16.7 5.6 1.3 1 0 0 1 1 1 1 ZW10 interactor NPV_P10 PF05531.12 EER23562.1 - 0.0028 18.1 9.0 0.14 12.7 2.2 3.0 3 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 EER23562.1 - 0.0042 17.4 9.5 0.015 15.6 0.0 3.6 3 1 1 4 4 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 EER23562.1 - 0.005 17.2 8.9 0.47 10.9 0.0 3.8 3 1 1 4 4 4 2 Flagella accessory protein C (FlaC) DUF848 PF05852.11 EER23562.1 - 0.0075 16.4 4.7 0.021 15.0 4.1 2.0 2 1 1 3 3 3 1 Gammaherpesvirus protein of unknown function (DUF848) Alpha-2-MRAP_C PF06401.11 EER23562.1 - 0.07 13.1 4.1 0.071 13.1 1.5 2.0 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain FapA PF03961.13 EER23562.1 - 0.11 11.1 6.6 0.41 9.2 1.4 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4844 PF16133.5 EER23562.1 - 0.12 12.9 1.8 0.31 11.6 1.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4844) Cob_adeno_trans PF01923.18 EER23562.1 - 0.14 12.3 4.0 0.27 11.4 0.7 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF4208 PF13907.6 EER23562.1 - 0.22 12.0 2.9 0.21 12.1 0.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4208) Baculo_PEP_C PF04513.12 EER23562.1 - 0.59 10.2 5.3 11 6.1 1.7 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Spc19 PF08287.11 EER23562.1 - 0.76 9.7 7.3 4.7 7.1 6.6 2.2 1 1 1 2 2 2 0 Spc19 Atg14 PF10186.9 EER23562.1 - 1 8.4 6.4 2.4 7.2 6.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EER23562.1 - 1.2 8.4 7.8 1.7 7.9 7.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.21 EER23562.1 - 2.3 8.4 9.1 2.8 8.1 0.0 3.7 3 1 1 4 4 4 0 bZIP transcription factor APG6_N PF17675.1 EER23562.1 - 2.8 8.5 13.7 5.7 7.5 1.8 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region XhlA PF10779.9 EER23562.1 - 6.4 7.1 6.6 17 5.7 0.0 3.2 2 1 1 3 3 3 0 Haemolysin XhlA CCDC-167 PF15188.6 EER23562.1 - 8 6.9 7.1 3.1 8.2 0.1 3.0 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DASH_Dam1 PF08653.10 EER23562.1 - 8.3 6.3 7.3 4.8 7.1 0.1 3.3 4 0 0 4 4 3 0 DASH complex subunit Dam1 SAPS PF04499.15 EER23563.1 - 3.3e-151 504.4 0.1 1.6e-114 383.4 0.0 2.8 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein Mpp10 PF04006.12 EER23563.1 - 0.15 10.5 5.6 0.38 9.2 5.6 1.6 1 0 0 1 1 1 0 Mpp10 protein SET PF00856.28 EER23564.1 - 0.00035 21.0 0.0 0.0007 20.0 0.0 1.5 1 0 0 1 1 1 1 SET domain Complex1_51K PF01512.17 EER23565.1 - 1.9e-47 161.0 0.0 3.6e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EER23565.1 - 5.1e-29 100.2 1.2 1.6e-28 98.6 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EER23565.1 - 1.3e-08 34.6 0.0 2.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 SLBB domain DUF3568 PF12092.8 EER23565.1 - 0.24 11.5 2.1 0.36 10.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) Nup96 PF12110.8 EER23566.1 - 5.6e-77 258.7 0.0 8.1e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EER23566.1 - 4e-52 176.3 0.0 6.4e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase AMP-binding PF00501.28 EER23567.1 - 2.9e-89 299.6 0.0 3.8e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER23567.1 - 2.4e-27 95.7 0.2 9.1e-26 90.7 0.3 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EER23567.1 - 4.8e-17 61.6 0.1 1.3e-16 60.3 0.1 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus GET2 PF08690.10 EER23568.1 - 1.2e-16 61.3 0.0 1.9e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 GET complex subunit GET2 C2 PF00168.30 EER23569.1 - 1.7e-26 92.5 0.0 1.6e-16 60.5 0.0 2.5 2 0 0 2 2 2 2 C2 domain Macoilin PF09726.9 EER23570.1 - 0.37 9.3 4.4 0.62 8.5 4.4 1.3 1 0 0 1 1 1 0 Macoilin family DUF4614 PF15391.6 EER23570.1 - 7.4 6.5 15.1 0.82 9.6 8.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) IMS_C PF11799.8 EER23571.1 - 1.3e-14 54.9 0.1 2.8e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.20 EER23571.1 - 4e-06 26.9 0.0 9.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family Reprolysin_2 PF13574.6 EER23572.1 - 7.7e-69 231.5 0.0 1.7e-68 230.4 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EER23572.1 - 2e-62 210.9 0.1 2e-62 210.9 0.1 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EER23572.1 - 1e-45 155.9 0.0 1.5e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EER23572.1 - 1.3e-16 61.1 31.7 1.3e-16 61.1 31.7 4.4 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 EER23572.1 - 3.2e-11 43.8 0.0 2.5e-10 40.9 0.0 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like ADAM_CR_2 PF17771.1 EER23572.1 - 4.8e-05 23.8 5.3 4.8e-05 23.8 5.3 4.6 2 2 2 4 4 4 1 ADAM cysteine-rich domain Pep_M12B_propep PF01562.19 EER23572.1 - 0.041 14.1 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide EF-hand_7 PF13499.6 EER23573.1 - 5.8e-16 58.7 1.5 5e-10 39.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EER23573.1 - 8.7e-15 53.1 0.9 1.5e-05 24.2 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EER23573.1 - 3.5e-14 51.4 2.1 6.9e-06 25.6 0.1 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EER23573.1 - 1.9e-11 43.6 1.6 9.7e-09 34.9 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair DUF3572 PF12096.8 EER23573.1 - 0.013 15.7 0.1 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) EF-hand_5 PF13202.6 EER23573.1 - 0.062 12.8 4.9 1.6 8.4 0.1 2.8 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.7 EER23573.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF4106 PF13388.6 EER23573.1 - 0.12 11.6 1.2 0.17 11.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) EFhand_Ca_insen PF08726.10 EER23573.1 - 0.21 11.7 0.1 0.63 10.2 0.0 1.8 2 0 0 2 2 2 0 Ca2+ insensitive EF hand KH_1 PF00013.29 EER23574.1 - 5.2e-47 157.5 11.7 2.4e-15 56.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EER23574.1 - 5.6e-13 48.5 0.7 0.0053 16.6 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EER23574.1 - 3.5e-09 36.4 4.5 0.025 14.4 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EER23574.1 - 0.003 17.6 2.4 11 6.2 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 EER23574.1 - 0.01 15.8 0.0 4.8 7.2 0.0 3.2 3 0 0 3 3 3 0 KH-like RNA-binding domain DUF802 PF05650.11 EER23574.1 - 0.53 10.8 3.2 0.54 10.8 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF802) Aminotran_1_2 PF00155.21 EER23575.1 - 1.4e-55 189.0 0.0 4.8e-55 187.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II DsbC_N PF10411.9 EER23575.1 - 0.063 12.7 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Disulfide bond isomerase protein N-terminus BrnT_toxin PF04365.13 EER23575.1 - 0.14 12.5 0.0 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system MgsA_C PF12002.8 EER23576.1 - 1.1e-58 197.8 0.0 1.9e-58 197.1 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EER23576.1 - 2.9e-22 78.8 0.3 7.3e-22 77.5 0.1 1.7 2 0 0 2 2 1 1 AAA C-terminal domain AAA PF00004.29 EER23576.1 - 1.1e-13 51.7 0.0 2.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EER23576.1 - 2.7e-10 40.2 0.0 5.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EER23576.1 - 3.9e-05 23.1 0.1 0.12 11.7 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EER23576.1 - 9.2e-05 22.2 0.1 0.0064 16.2 0.1 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EER23576.1 - 0.00014 21.8 0.1 0.0022 18.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EER23576.1 - 0.00045 20.1 0.0 0.0012 18.7 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EER23576.1 - 0.00076 19.9 0.2 0.28 11.6 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EER23576.1 - 0.0041 16.3 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.6 EER23576.1 - 0.0065 16.2 0.3 0.016 14.9 0.3 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EER23576.1 - 0.011 16.1 0.2 0.027 14.8 0.2 1.6 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EER23576.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EER23576.1 - 0.016 15.3 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EER23576.1 - 0.016 15.5 0.1 0.062 13.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 EER23576.1 - 0.024 13.9 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ResIII PF04851.15 EER23576.1 - 0.026 14.5 0.8 1.1 9.2 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.6 EER23576.1 - 0.059 13.1 0.1 3.8 7.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf_UBZ PF18439.1 EER23576.1 - 0.064 12.9 0.3 0.47 10.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger SKI PF01202.22 EER23576.1 - 0.065 13.4 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Shikimate kinase TsaE PF02367.17 EER23576.1 - 0.077 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE zf_C2H2_13 PF18508.1 EER23576.1 - 0.099 12.2 1.3 0.19 11.3 1.3 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-C2H2 PF00096.26 EER23576.1 - 0.14 12.7 0.0 0.4 11.2 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type AAA_24 PF13479.6 EER23576.1 - 0.21 11.3 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 EER23576.1 - 0.22 10.6 0.1 0.37 9.9 0.1 1.3 1 0 0 1 1 1 0 PIF1-like helicase Zn_clus PF00172.18 EER23577.1 - 0.037 14.1 11.3 0.087 13.0 11.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_E4 PF05385.11 EER23577.1 - 0.18 11.9 0.3 0.39 10.8 0.3 1.6 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein Ald_Xan_dh_C2 PF02738.18 EER23580.1 - 1.2e-206 687.4 0.6 1.8e-206 686.9 0.6 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EER23580.1 - 1.4e-44 151.9 0.0 2.7e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EER23580.1 - 1.6e-34 118.1 0.0 1.2e-33 115.3 0.0 2.5 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.20 EER23580.1 - 1e-29 102.3 0.0 2.2e-29 101.3 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.22 EER23580.1 - 8.8e-29 100.1 0.0 2.2e-28 98.8 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.27 EER23580.1 - 1.5e-08 34.5 0.1 1.5e-08 34.5 0.1 2.6 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r4 PF04545.16 EER23580.1 - 0.12 11.9 0.0 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 NAD_binding_4 PF07993.12 EER23582.1 - 1.7e-69 233.9 0.0 2.4e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EER23582.1 - 1.3e-66 225.0 0.0 2e-66 224.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EER23582.1 - 3.7e-10 39.1 0.0 4e-09 35.7 0.0 2.0 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 EER23582.1 - 1.3e-08 34.7 0.0 3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EER23582.1 - 5.8e-08 33.0 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EER23582.1 - 7.3e-05 23.7 0.0 0.00071 20.5 0.0 2.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 EER23582.1 - 0.0001 21.4 0.0 0.00022 20.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EER23582.1 - 0.00054 19.9 0.1 0.015 15.2 0.1 2.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EER23582.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ABC_tran PF00005.27 EER23583.1 - 0.00077 20.0 0.0 0.0019 18.8 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EER23583.1 - 0.016 15.6 0.6 0.044 14.2 0.6 1.9 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 EER23583.1 - 0.041 13.6 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EER23583.1 - 0.069 13.7 0.1 0.26 11.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 EER23583.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_29 PF13555.6 EER23583.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EER23583.1 - 0.42 10.8 2.8 0.39 10.9 0.5 2.1 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.23 EER23584.1 - 3.9e-41 140.9 0.1 1.4e-35 122.7 0.0 2.6 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EER23584.1 - 1.3e-06 28.8 0.0 2.4e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MFS_1 PF07690.16 EER23585.1 - 3.5e-43 147.9 34.3 1.5e-40 139.2 21.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Mid2 PF04478.12 EER23586.1 - 5.8e-05 23.0 0.1 9.5e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EER23586.1 - 0.001 18.4 0.5 0.001 18.4 0.5 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2207 PF09972.9 EER23586.1 - 0.029 13.2 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HMG_box PF00505.19 EER23587.1 - 2.5e-23 82.2 0.4 4.7e-23 81.4 0.4 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EER23587.1 - 2.2e-09 37.8 0.2 5.1e-09 36.6 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 EER23587.1 - 0.027 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 CHDNT (NUC034) domain Lipase_GDSL PF00657.22 EER23588.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Ribosomal_S6e PF01092.19 EER23589.1 - 2.4e-56 189.1 0.0 4.8e-56 188.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.6 EER23590.1 - 3.7e-46 155.8 0.3 2.8e-45 153.0 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EER23590.1 - 2e-43 148.6 2.0 9.6e-37 126.8 0.9 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EER23590.1 - 5.9e-18 64.9 0.8 6.2e-16 58.3 0.4 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 EER23590.1 - 0.0088 15.5 0.2 0.015 14.7 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.12 EER23591.1 - 2.1e-124 415.2 0.0 2.1e-124 415.2 0.0 5.7 6 1 0 6 6 6 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EER23591.1 - 7.9e-117 390.7 0.6 7.9e-117 390.7 0.6 3.9 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EER23591.1 - 5.1e-95 318.5 0.0 8.9e-95 317.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EER23591.1 - 9.3e-28 94.8 32.7 3.9e-10 38.8 0.6 4.3 4 0 0 4 4 4 3 Ubiquitin binding region UBA PF00627.31 EER23591.1 - 0.014 15.2 0.0 0.067 13.1 0.0 2.2 2 0 0 2 2 2 0 UBA/TS-N domain An_peroxidase PF03098.15 EER23592.1 - 1.4e-38 132.8 0.0 1.7e-28 99.5 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EER23592.1 - 7.6e-08 31.5 0.0 1.5e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Steroid_dh PF02544.16 EER23593.1 - 4.9e-32 111.0 0.6 6.7e-32 110.5 0.6 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EER23593.1 - 1.4e-06 28.1 0.2 2.1e-06 27.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EER23593.1 - 3.7e-05 24.1 0.3 7.4e-05 23.1 0.3 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase Glyco_transf_34 PF05637.12 EER23594.1 - 1.3e-61 208.4 0.0 1.7e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ABC2_membrane_3 PF12698.7 EER23594.1 - 0.076 12.1 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Ribosomal_L28 PF00830.19 EER23595.1 - 2.5e-17 62.8 0.4 5e-17 61.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.13 EER23596.1 - 5.4e-167 555.4 0.1 6.5e-167 555.1 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EER23596.1 - 6.5e-20 71.0 0.0 2.7e-19 69.0 0.0 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EER23596.1 - 2.6e-11 44.1 0.3 3.3e-07 30.8 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EER23596.1 - 1.2e-10 41.4 0.1 4.1e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EER23596.1 - 1.7e-05 25.1 0.1 0.043 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EER23596.1 - 0.00012 22.5 0.9 0.062 13.6 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EER23596.1 - 0.00016 22.1 0.2 0.0029 18.0 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EER23596.1 - 0.00044 20.5 0.1 0.0011 19.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EER23596.1 - 0.00053 20.0 0.2 0.14 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EER23596.1 - 0.00083 19.1 0.1 0.73 9.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain DnaB_C PF03796.15 EER23596.1 - 0.0041 16.5 0.1 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 EER23596.1 - 0.0045 16.3 0.2 0.013 14.7 0.2 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.6 EER23596.1 - 0.0057 17.1 0.2 0.087 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EER23596.1 - 0.0066 16.0 0.1 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EER23596.1 - 0.013 14.9 0.1 0.61 9.4 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EER23596.1 - 0.023 14.1 0.8 0.14 11.5 0.1 2.1 2 0 0 2 2 2 0 KaiC IstB_IS21 PF01695.17 EER23596.1 - 0.025 14.3 0.2 0.052 13.3 0.2 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 EER23596.1 - 0.04 13.2 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TetR_C_30 PF17939.1 EER23596.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_18 PF13238.6 EER23596.1 - 0.043 14.4 0.1 0.19 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EER23596.1 - 0.068 13.1 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA_7 PF12775.7 EER23596.1 - 0.1 12.1 0.1 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EER23596.1 - 0.12 12.4 0.1 0.25 11.3 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EER23596.1 - 0.17 11.6 1.5 1.6 8.4 0.1 2.5 3 0 0 3 3 3 0 AAA domain ResIII PF04851.15 EER23596.1 - 0.18 11.8 0.1 8.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NAD_binding_8 PF13450.6 EER23597.1 - 5.5e-09 36.1 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER23597.1 - 0.00079 19.1 0.2 0.0014 18.3 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EER23597.1 - 0.0044 16.4 0.0 2.4 7.3 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EER23597.1 - 0.021 14.8 0.0 0.35 10.9 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EER23597.1 - 0.031 13.5 0.0 0.19 11.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EER23597.1 - 0.036 13.4 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 EER23597.1 - 0.053 11.9 0.0 0.076 11.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.22 EER23597.1 - 0.31 10.1 0.2 0.51 9.4 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A V-SNARE PF05008.15 EER23598.1 - 8e-22 77.4 5.2 8e-22 77.4 5.2 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EER23598.1 - 1.1e-16 60.9 3.1 1.1e-16 60.9 3.1 3.4 3 1 1 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EER23598.1 - 0.0088 15.9 1.5 0.017 15.0 0.1 2.2 2 2 0 2 2 2 1 Sec20 Prominin PF05478.11 EER23598.1 - 0.011 13.7 1.5 0.14 10.1 0.2 2.1 2 0 0 2 2 2 0 Prominin Fusion_gly PF00523.18 EER23598.1 - 0.016 13.5 3.4 0.17 10.1 0.3 2.4 2 1 0 2 2 2 0 Fusion glycoprotein F0 COG7 PF10191.9 EER23598.1 - 0.019 13.3 0.5 0.026 12.8 0.5 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Histidinol_dh PF00815.20 EER23598.1 - 0.089 11.8 1.1 0.14 11.2 1.1 1.3 1 0 0 1 1 1 0 Histidinol dehydrogenase Synaptobrevin PF00957.21 EER23598.1 - 0.39 10.5 0.1 0.39 10.5 0.1 2.6 4 0 0 4 4 4 0 Synaptobrevin SNARE PF05739.19 EER23598.1 - 0.39 10.8 3.5 0.38 10.8 0.6 2.3 2 0 0 2 2 2 0 SNARE domain SKA2 PF16740.5 EER23598.1 - 0.39 10.5 8.0 1.3 8.8 2.5 2.7 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 Atg14 PF10186.9 EER23598.1 - 0.52 9.3 9.8 0.59 9.2 9.0 1.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YqjK PF13997.6 EER23598.1 - 0.99 9.7 4.1 10 6.5 0.0 2.7 2 0 0 2 2 2 0 YqjK-like protein DUF349 PF03993.12 EER23598.1 - 1.6 9.1 9.8 0.98 9.8 0.6 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) Exonuc_VII_L PF02601.15 EER23598.1 - 5.2 6.5 11.2 20 4.6 11.2 1.8 1 1 0 1 1 1 0 Exonuclease VII, large subunit zf-C4H2 PF10146.9 EER23598.1 - 6.3 7.0 7.6 21 5.4 7.5 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein DUF2407_C PF13373.6 EER23599.1 - 2e-43 147.9 0.1 2.9e-43 147.4 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EER23599.1 - 4e-31 107.6 0.0 6.6e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EER23599.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Fe-S_biosyn PF01521.20 EER23600.1 - 3.8e-22 78.6 0.0 6.7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3128 PF11326.8 EER23600.1 - 0.0054 17.1 0.0 0.007 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) EBP50_C PF09007.11 EER23600.1 - 0.23 12.4 4.3 0.39 11.7 0.4 2.3 2 0 0 2 2 2 0 EBP50, C-terminal DUF1741 PF08427.10 EER23601.1 - 7e-91 304.0 0.3 1.1e-90 303.4 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) TipAS PF07739.13 EER23601.1 - 0.028 15.0 0.0 0.096 13.2 0.0 1.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain MRG PF05712.13 EER23602.1 - 6.5e-57 192.0 0.2 1.2e-56 191.2 0.2 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EER23602.1 - 2.2e-08 33.8 2.5 6e-08 32.5 2.5 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 EER23602.1 - 0.029 14.3 3.6 0.13 12.2 3.6 2.2 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RNA_pol_3_Rpc31 PF11705.8 EER23602.1 - 6.9 6.9 30.1 0.025 14.9 14.3 2.8 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Myc_N PF01056.18 EER23602.1 - 8.6 6.1 12.6 2.8 7.7 6.6 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Cnl2_NKP2 PF09447.10 EER23603.1 - 1.3e-27 95.7 1.9 1.3e-27 95.7 1.9 1.8 2 0 0 2 2 2 1 Cnl2/NKP2 family protein Mod_r PF07200.13 EER23603.1 - 0.0037 17.4 2.6 0.0066 16.6 2.6 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF4446 PF14584.6 EER23603.1 - 0.041 13.9 0.1 2.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Prefoldin_2 PF01920.20 EER23603.1 - 0.11 12.5 7.3 0.98 9.4 0.1 2.7 2 1 0 2 2 2 0 Prefoldin subunit YabA PF06156.13 EER23603.1 - 0.12 13.0 1.8 7.6 7.2 0.6 2.3 2 0 0 2 2 2 0 Initiation control protein YabA Qua1 PF16274.5 EER23603.1 - 0.25 11.2 2.2 5.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Qua1 domain ABC_tran_CTD PF16326.5 EER23603.1 - 0.4 11.0 3.9 3.4 8.0 0.3 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Tnp_22_trimer PF17489.2 EER23603.1 - 0.56 10.2 6.1 1.3 9.0 1.5 2.5 2 0 0 2 2 2 0 L1 transposable element trimerization domain Ctf8 PF09696.10 EER23605.1 - 9.9e-48 162.1 0.0 1.2e-47 161.9 0.0 1.0 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.25 EER23606.1 - 2.7e-21 76.1 0.0 1.8e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EER23606.1 - 7.7e-13 48.7 0.0 5e-06 26.7 0.0 2.6 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EER23606.1 - 9.1e-06 25.9 0.0 0.0055 16.9 0.0 3.1 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EER23606.1 - 3.1e-05 24.2 0.0 0.16 12.1 0.0 2.9 2 1 0 2 2 2 2 Glyoxalase-like domain RabGAP-TBC PF00566.18 EER23607.1 - 3.7e-52 177.1 0.3 7.9e-51 172.8 0.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 EER23607.1 - 1.4 9.1 23.8 0.38 10.9 9.2 3.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 Mago_nashi PF02792.14 EER23607.1 - 1.7 8.7 6.5 0.096 12.8 0.4 1.9 2 0 0 2 2 2 0 Mago nashi protein YabA PF06156.13 EER23607.1 - 7.4 7.3 21.3 0.76 10.4 3.8 3.3 2 1 1 3 3 3 0 Initiation control protein YabA PPTA PF01239.22 EER23608.1 - 2.6e-37 125.5 12.3 1.7e-07 30.7 0.1 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat WD40 PF00400.32 EER23609.1 - 3.1e-08 34.2 2.0 0.0013 19.6 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23609.1 - 9e-08 32.3 0.0 0.011 16.0 0.0 4.6 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EER23610.1 - 4.3e-24 84.9 0.2 8.9e-24 83.9 0.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EER23610.1 - 0.025 14.8 0.0 38 4.7 0.0 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Bromodomain PF00439.25 EER23611.1 - 2.8e-42 142.7 1.1 1.1e-20 73.4 0.4 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EER23611.1 - 4.9e-18 65.0 0.2 1.2e-17 63.8 0.2 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation PIEZO PF15917.5 EER23611.1 - 2.4 7.6 9.4 8.8 5.7 9.4 2.0 1 0 0 1 1 1 0 Piezo HAUS4 PF14735.6 EER23612.1 - 5.7e-08 32.7 2.5 5.7e-08 32.7 2.5 1.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 SOGA PF11365.8 EER23612.1 - 0.043 14.9 0.9 3 9.1 0.1 3.4 3 0 0 3 3 3 0 Protein SOGA Ribosomal_S30 PF04758.14 EER23612.1 - 2.5 8.3 5.5 0.6 10.3 0.6 2.3 2 0 0 2 2 2 0 Ribosomal protein S30 zf-CSL PF05207.13 EER23613.1 - 8.3e-22 76.7 0.1 1e-21 76.4 0.1 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 EER23613.1 - 0.027 14.7 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 C4-type zinc ribbon domain Frataxin_Cyay PF01491.16 EER23614.1 - 2.1e-35 121.1 0.0 2.8e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain DUF2543 PF10820.8 EER23614.1 - 0.051 13.7 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) AKAP7_NLS PF10469.9 EER23615.1 - 1.8e-15 57.4 0.0 2.7e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.13 EER23616.1 - 3.6e-177 590.2 4.0 5.6e-177 589.6 4.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 LprI PF07007.12 EER23616.1 - 0.15 12.8 1.0 0.51 11.0 0.2 2.4 2 0 0 2 2 2 0 Lysozyme inhibitor LprI HEAT_2 PF13646.6 EER23616.1 - 0.28 11.6 2.0 2.2 8.7 0.1 3.5 3 1 0 3 3 3 0 HEAT repeats Vps53_N PF04100.12 EER23616.1 - 0.41 9.6 10.9 0.52 9.2 2.8 2.7 3 0 0 3 3 3 0 Vps53-like, N-terminal PCRF PF03462.18 EER23616.1 - 7.3 6.4 7.0 13 5.6 1.7 2.5 1 1 1 2 2 2 0 PCRF domain Ribosomal_L30 PF00327.20 EER23617.1 - 1.7e-14 53.4 0.4 2.1e-14 53.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e KapB PF08810.10 EER23617.1 - 0.034 14.3 0.0 0.043 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase associated protein B Pyridoxal_deC PF00282.19 EER23618.1 - 3.5e-18 65.5 0.0 5.8e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EER23618.1 - 7.7e-07 28.4 0.0 1.6e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EER23618.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EER23618.1 - 0.06 12.5 0.0 0.094 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_1_2 PF00155.21 EER23619.1 - 1.5e-93 313.9 0.0 1.7e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_3 PF01494.19 EER23620.1 - 7.4e-22 78.1 0.0 1.3e-21 77.3 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EER23620.1 - 2.7e-06 27.2 0.6 0.0021 17.7 0.5 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EER23620.1 - 4.8e-06 26.0 0.3 0.00022 20.6 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER23620.1 - 2.5e-05 24.4 0.0 5.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EER23620.1 - 0.00011 21.4 1.1 0.00057 19.0 1.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EER23620.1 - 0.00035 19.8 0.9 0.001 18.3 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EER23620.1 - 0.0014 17.9 0.7 0.013 14.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER23620.1 - 0.032 13.5 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.14 EER23620.1 - 0.096 11.4 0.1 0.16 10.6 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EER23620.1 - 0.17 10.9 2.5 0.85 8.6 2.5 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A Bromo_TP PF07524.13 EER23621.1 - 5.4e-08 32.7 0.0 8.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EER23621.1 - 0.048 13.7 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit BRO1 PF03097.18 EER23622.1 - 4e-08 32.5 0.0 5.6e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain NDUFB10 PF10249.9 EER23623.1 - 0.029 14.9 0.0 0.038 14.5 0.0 1.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Glyco_transf_34 PF05637.12 EER23624.1 - 9.8e-63 212.1 0.1 1.4e-62 211.5 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PTR2 PF00854.21 EER23625.1 - 4e-88 295.9 11.4 6.1e-88 295.3 11.4 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EER23625.1 - 1.4e-13 50.5 15.4 4.8e-07 29.0 0.0 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TFR_dimer PF04253.15 EER23626.1 - 6.7e-27 94.0 0.0 1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EER23626.1 - 1.2e-21 77.3 0.0 2.2e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EER23626.1 - 5.6e-09 35.9 0.1 1.5e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 EER23626.1 - 0.033 13.9 0.0 0.074 12.7 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Pkinase PF00069.25 EER23627.1 - 5.7e-67 225.8 0.0 1.8e-66 224.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23627.1 - 1.2e-34 119.8 0.0 2e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EER23627.1 - 7.4e-10 39.0 0.2 4.1e-09 36.7 0.1 2.3 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EER23627.1 - 2.9e-05 24.3 0.0 7.5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EER23627.1 - 0.0063 15.9 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EER23627.1 - 0.014 14.2 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EER23627.1 - 0.018 15.0 0.0 4 7.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EER23627.1 - 0.037 13.3 0.0 0.12 11.6 0.0 1.8 1 1 0 1 1 1 0 Kinase-like Lact-deh-memb PF09330.11 EER23627.1 - 0.04 13.3 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding FTA2 PF13095.6 EER23627.1 - 0.06 13.0 0.2 0.11 12.1 0.2 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EER23627.1 - 0.13 11.1 0.1 0.21 10.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Beta_elim_lyase PF01212.21 EER23628.1 - 2.4e-60 204.3 0.0 3.3e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EER23628.1 - 0.0093 14.5 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RNase_T PF00929.24 EER23629.1 - 6.4e-09 36.6 0.0 1.1e-08 35.8 0.0 1.4 1 0 0 1 1 1 1 Exonuclease MFS_1 PF07690.16 EER23630.1 - 2e-12 46.7 60.4 1.1e-10 40.9 59.4 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EER23630.1 - 3.3e-06 25.8 23.0 5.2e-06 25.2 23.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acetyltransf_8 PF13523.6 EER23631.1 - 1.1e-41 141.9 1.4 2.3e-20 72.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 EER23632.1 - 5e-91 305.4 0.0 7.6e-91 304.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER23632.1 - 3.9e-15 56.6 0.0 7.3e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.6 EER23633.1 - 6.1e-123 410.3 0.0 7.1e-123 410.1 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EER23633.1 - 4.2e-10 39.3 0.0 1.3e-07 31.2 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER23633.1 - 9.4e-07 28.4 0.0 0.00017 21.0 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER23633.1 - 2.2e-06 27.7 0.3 0.0014 18.6 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EER23633.1 - 0.0041 17.7 0.0 0.33 11.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EER23633.1 - 0.065 12.3 0.2 9.1 5.2 0.1 2.2 1 1 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EER23633.1 - 0.11 12.8 0.7 0.43 10.9 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EER23633.1 - 0.14 11.4 0.1 2.6 7.2 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 EER23634.1 - 2.4e-22 79.5 0.0 8.5e-22 77.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER23634.1 - 4e-07 30.5 0.8 7.1e-06 26.5 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER23634.1 - 0.0036 17.3 1.0 12 5.9 0.0 3.8 3 1 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EER23634.1 - 0.0046 16.2 0.0 0.018 14.2 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EER23634.1 - 0.0063 16.1 0.0 2.6 7.5 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EER23634.1 - 0.011 15.0 1.6 0.34 10.1 0.9 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EER23634.1 - 0.039 13.3 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase DUF4881 PF16222.5 EER23634.1 - 0.05 13.4 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) Lycopene_cycl PF05834.12 EER23634.1 - 0.081 12.0 1.2 1.7 7.6 0.2 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 EER23634.1 - 0.9 8.5 2.3 34 3.3 0.3 3.1 3 1 1 4 4 4 0 Glucose inhibited division protein A ABC_membrane PF00664.23 EER23635.1 - 5.7e-95 318.1 34.9 1.2e-49 169.4 11.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EER23635.1 - 1.6e-66 223.0 0.0 2.1e-32 112.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EER23635.1 - 8.6e-15 54.8 2.9 2.2e-05 24.0 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EER23635.1 - 1.3e-07 31.3 0.5 0.0057 16.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EER23635.1 - 4e-07 30.6 0.2 0.063 13.7 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EER23635.1 - 1.3e-06 28.7 0.2 0.27 11.5 0.0 4.0 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 EER23635.1 - 3.5e-06 26.4 0.0 0.046 13.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EER23635.1 - 1.8e-05 24.7 0.1 0.057 13.3 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EER23635.1 - 6.1e-05 23.5 0.2 0.52 10.7 0.1 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EER23635.1 - 0.00015 20.7 0.5 0.018 13.9 0.0 2.9 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_30 PF13604.6 EER23635.1 - 0.00028 20.7 0.9 0.087 12.5 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EER23635.1 - 0.00041 20.1 0.0 0.25 11.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EER23635.1 - 0.00043 20.5 0.0 0.6 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 EER23635.1 - 0.00067 19.3 0.1 2.3 7.7 0.0 3.1 4 0 0 4 4 4 2 AAA domain SbcCD_C PF13558.6 EER23635.1 - 0.0008 19.6 0.6 3 8.1 0.0 3.6 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 EER23635.1 - 0.0012 18.7 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EER23635.1 - 0.0014 18.5 1.0 0.21 11.4 0.1 3.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EER23635.1 - 0.0016 19.0 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EER23635.1 - 0.0017 18.5 0.1 0.3 11.1 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 EER23635.1 - 0.0022 18.6 0.0 2.5 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 EER23635.1 - 0.0071 15.4 0.0 0.64 9.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) APS_kinase PF01583.20 EER23635.1 - 0.0093 15.9 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.14 EER23635.1 - 0.013 15.5 0.0 2.3 8.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EER23635.1 - 0.019 14.5 0.0 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EER23635.1 - 0.03 14.4 0.0 8.5 6.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EER23635.1 - 0.044 14.2 0.0 42 4.6 0.0 3.5 3 0 0 3 3 3 0 RNA helicase AAA_17 PF13207.6 EER23635.1 - 0.046 14.1 0.1 16 5.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain ECH_2 PF16113.5 EER23635.1 - 0.051 13.1 0.1 0.99 8.8 0.0 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase G-alpha PF00503.20 EER23635.1 - 0.1 11.8 0.0 3.6 6.6 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.22 EER23635.1 - 0.17 11.1 0.0 12 4.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AMP-binding PF00501.28 EER23636.1 - 1.9e-72 244.2 0.0 4.1e-72 243.1 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme Condensation PF00668.20 EER23636.1 - 3.2e-62 210.7 0.0 1.8e-36 125.8 0.0 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EER23636.1 - 5.1e-29 100.4 0.1 7e-13 48.7 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site OPT PF03169.15 EER23637.1 - 1.9e-180 601.5 48.5 2.3e-180 601.3 48.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TetR_C_16 PF17920.1 EER23637.1 - 0.038 14.2 0.3 0.083 13.1 0.0 1.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glutaredoxin PF00462.24 EER23638.1 - 5.6e-19 68.1 0.0 5.2e-18 65.0 0.0 2.3 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EER23638.1 - 9.1e-13 48.1 0.0 2.7e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EER23638.1 - 0.00059 20.1 0.0 0.48 10.8 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EER23638.1 - 0.078 13.4 0.0 0.44 11.0 0.0 2.2 2 2 0 2 2 2 0 Thioredoxin-like domain OST3_OST6 PF04756.13 EER23638.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TauD PF02668.16 EER23639.1 - 1.4e-44 152.9 0.1 1.9e-44 152.5 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EER23639.1 - 5.6e-05 23.7 0.2 0.00016 22.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 EER23639.1 - 0.032 13.3 0.0 0.051 12.7 0.0 1.4 1 1 0 1 1 1 0 CsiD Ank_2 PF12796.7 EER23640.1 - 1.4e-50 169.7 1.3 1e-09 38.8 0.0 7.9 4 2 4 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER23640.1 - 3.4e-48 161.4 4.5 4.7e-08 33.4 0.0 9.7 6 3 2 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EER23640.1 - 1.2e-35 121.0 8.6 1.7e-06 28.2 0.0 11.7 8 2 4 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER23640.1 - 6.8e-35 115.1 0.3 0.0025 18.1 0.0 12.9 13 0 0 13 13 13 6 Ankyrin repeat Ank PF00023.30 EER23640.1 - 2.2e-21 75.3 14.7 0.0048 17.3 0.0 12.1 10 2 2 12 12 12 5 Ankyrin repeat F-box PF00646.33 EER23640.1 - 0.045 13.6 0.6 0.11 12.4 0.6 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EER23640.1 - 0.072 13.0 0.4 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 F-box-like Mur_ligase PF01225.25 EER23640.1 - 0.076 13.3 0.1 11 6.4 0.0 3.3 3 0 0 3 3 3 0 Mur ligase family, catalytic domain GDPD_2 PF13653.6 EER23640.1 - 0.58 10.7 2.1 8.1 7.1 0.0 3.3 3 0 0 3 3 3 0 Glycerophosphoryl diester phosphodiesterase family Mito_carr PF00153.27 EER23641.1 - 1.5e-65 217.2 2.3 2.5e-22 78.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EER23641.1 - 0.01 15.0 2.3 2.7 7.1 0.1 3.7 3 1 0 4 4 4 0 Gammaproteobacterial serine protease UT PF03253.14 EER23641.1 - 0.06 12.5 0.8 0.083 12.0 0.2 1.4 2 0 0 2 2 2 0 Urea transporter Tubulin PF00091.25 EER23642.1 - 4.3e-65 219.6 0.0 5.8e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EER23642.1 - 2e-44 150.8 0.0 3e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EER23642.1 - 0.00045 19.9 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.18 EER23643.1 - 3.1e-24 85.7 3.2 5e-24 85.0 3.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 EER23643.1 - 2e-05 23.9 0.1 6.1e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 EER23643.1 - 0.00027 20.3 0.6 0.00059 19.2 0.6 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EER23643.1 - 0.00075 19.2 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EER23643.1 - 0.0047 17.4 0.2 0.013 15.9 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair OB_NTP_bind PF07717.16 EER23643.1 - 0.17 12.2 0.1 0.44 10.9 0.1 1.6 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC2_membrane PF01061.24 EER23644.1 - 5.9e-90 300.3 56.3 6.6e-47 159.6 24.4 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EER23644.1 - 3.4e-37 128.0 0.0 2.7e-17 63.6 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EER23644.1 - 1.9e-35 120.6 1.9 4.8e-31 106.5 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EER23644.1 - 5.7e-18 65.3 0.6 1.3e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_25 PF13481.6 EER23644.1 - 1.5e-06 27.9 0.0 2.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EER23644.1 - 7.2e-06 26.5 0.0 0.009 16.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EER23644.1 - 4.4e-05 23.4 0.1 0.0045 16.9 0.0 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EER23644.1 - 0.00014 22.1 0.1 0.033 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EER23644.1 - 0.00045 20.8 0.0 0.021 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EER23644.1 - 0.0049 16.6 3.1 0.067 12.9 0.1 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EER23644.1 - 0.005 16.7 0.0 2.2 8.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EER23644.1 - 0.0058 15.8 49.7 0.087 11.9 25.3 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein NACHT PF05729.12 EER23644.1 - 0.011 15.6 0.4 2.3 8.1 0.1 3.0 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 EER23644.1 - 0.014 15.7 0.6 2.2 8.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EER23644.1 - 0.016 14.6 0.1 0.51 9.7 0.0 2.8 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EER23644.1 - 0.017 14.8 0.3 2.2 8.0 0.1 2.6 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EER23644.1 - 0.062 12.9 0.8 0.4 10.3 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EER23644.1 - 0.12 12.8 0.4 2.8 8.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EER23644.1 - 0.15 12.1 0.1 34 4.6 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EER23644.1 - 0.2 11.4 0.4 19 4.9 0.2 2.6 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 EER23644.1 - 0.21 11.3 0.0 5.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sina PF03145.16 EER23645.1 - 0.81 9.6 8.5 1.5 8.8 0.6 2.3 2 0 0 2 2 2 0 Seven in absentia protein family zf-C2H2 PF00096.26 EER23645.1 - 1.3 9.6 15.8 2.7 8.6 0.7 4.2 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER23645.1 - 4 8.5 20.1 0.51 11.3 0.3 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger CYSTM PF12734.7 EER23646.1 - 3.1e-12 46.6 19.8 3.1e-12 46.6 19.8 4.4 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance XYPPX PF02162.17 EER23646.1 - 0.086 12.7 25.8 0.086 12.7 25.8 3.5 2 2 1 3 3 3 0 XYPPX repeat (two copies) Pex14_N PF04695.13 EER23646.1 - 0.23 12.1 6.0 0.23 12.1 6.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribul_P_3_epim PF00834.19 EER23647.1 - 5.4e-64 215.2 0.0 1e-62 211.1 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 EER23647.1 - 0.018 14.4 0.4 0.026 13.9 0.4 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.24 EER23647.1 - 0.051 13.1 0.1 0.098 12.2 0.1 1.5 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family SH3BGR PF04908.15 EER23648.1 - 0.004 17.3 0.0 0.013 15.7 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Hamartin PF04388.12 EER23648.1 - 6.3 5.3 14.5 7.6 5.1 14.5 1.0 1 0 0 1 1 1 0 Hamartin protein DUF4551 PF15087.6 EER23648.1 - 9.8 4.9 8.8 12 4.6 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-BED PF02892.15 EER23649.1 - 0.00016 21.6 2.5 0.026 14.6 0.1 2.8 2 0 0 2 2 2 2 BED zinc finger Methyltransf_11 PF08241.12 EER23650.1 - 1.3e-07 32.1 0.0 5.2e-07 30.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23650.1 - 0.00035 21.2 0.0 0.016 15.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain LSM PF01423.22 EER23651.1 - 4e-18 64.9 1.1 5.2e-18 64.5 1.1 1.2 1 0 0 1 1 1 1 LSM domain LRR_9 PF14580.6 EER23651.1 - 0.0048 16.4 0.1 0.0053 16.3 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat SM-ATX PF14438.6 EER23651.1 - 0.035 14.3 0.0 0.041 14.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 EER23651.1 - 0.048 13.3 0.1 0.078 12.6 0.1 1.3 1 0 0 1 1 1 0 Hfq protein DRMBL PF07522.14 EER23652.1 - 7.2e-36 122.7 0.0 1.5e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EER23652.1 - 1.2e-06 28.2 0.0 2.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GST_N_3 PF13417.6 EER23653.1 - 7.2e-10 39.2 0.0 1.2e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EER23653.1 - 5.2e-07 29.9 0.0 8.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EER23653.1 - 2.3e-05 24.7 0.0 0.00096 19.4 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.16 EER23654.1 - 8.1e-28 97.3 29.6 8.1e-28 97.3 29.6 1.8 1 1 1 3 3 3 1 Major Facilitator Superfamily DUF2530 PF10745.9 EER23654.1 - 0.47 10.7 11.3 0.073 13.3 1.5 3.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) CECR6_TMEM121 PF14997.6 EER23655.1 - 0.65 9.8 5.4 0.44 10.4 1.5 2.1 2 0 0 2 2 2 0 CECR6/TMEM121 family Wzy_C PF04932.15 EER23655.1 - 3.1 7.4 7.9 6.3 6.4 2.1 2.4 2 1 0 2 2 2 0 O-Antigen ligase FAD_binding_4 PF01565.23 EER23656.1 - 6.2e-36 123.2 5.6 1.4e-35 122.1 3.4 2.4 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.12 EER23656.1 - 8.9e-07 28.9 0.0 2.1e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 EER23657.1 - 6.7e-64 216.3 0.0 8.6e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TLP1_add_C PF18313.1 EER23658.1 - 1.4e-26 92.2 0.1 6.2e-26 90.2 0.0 2.0 2 0 0 2 2 2 1 Thiolase-like protein type 1 additional C-terminal domain COesterase PF00135.28 EER23659.1 - 2.8e-92 310.2 0.0 2.4e-59 201.6 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EER23659.1 - 2.6e-06 27.4 0.1 0.00062 19.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold F-actin_cap_A PF01267.17 EER23660.1 - 3.8e-94 315.0 0.0 4.3e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Endonuc-MspI PF09208.10 EER23660.1 - 0.048 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease MspI Peptidase_M14 PF00246.24 EER23661.1 - 1.7e-78 264.4 0.1 2.1e-78 264.0 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EER23661.1 - 5.9e-12 45.8 0.1 6.4e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Peptidase_S8 PF00082.22 EER23662.1 - 3.3e-27 95.5 10.0 5.5e-27 94.8 10.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER23662.1 - 6.1e-20 71.7 0.1 1.5e-19 70.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase inhibitor I9 Exotox-A_cataly PF09009.10 EER23662.1 - 0.11 12.3 1.0 0.23 11.2 0.3 1.8 2 0 0 2 2 2 0 Exotoxin A catalytic FSH1 PF03959.13 EER23664.1 - 2e-05 24.3 0.0 6.5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) PP-binding PF00550.25 EER23665.1 - 0.044 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site PAP2 PF01569.21 EER23666.1 - 5.3e-25 87.8 0.8 1e-24 86.8 0.8 1.5 1 0 0 1 1 1 1 PAP2 superfamily DUF5510 PF17629.2 EER23666.1 - 0.034 14.1 0.6 0.096 12.6 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5510) Med7 PF05983.11 EER23667.1 - 4.7e-64 216.0 6.5 6.2e-64 215.6 6.5 1.2 1 0 0 1 1 1 1 MED7 protein CENP-Q PF13094.6 EER23667.1 - 0.015 15.5 2.5 0.015 15.5 2.5 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DNA_pol_A_exoN PF18305.1 EER23667.1 - 0.044 14.1 0.5 0.1 12.9 0.5 1.6 1 0 0 1 1 1 0 3' to 5' exonuclease C-terminal domain DUF87 PF01935.17 EER23667.1 - 0.095 12.8 0.6 0.13 12.4 0.6 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Prefoldin_2 PF01920.20 EER23667.1 - 0.7 9.9 8.2 0.15 12.0 3.9 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF5327 PF17261.2 EER23667.1 - 1.5 9.6 6.9 0.92 10.3 3.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) Spc24 PF08286.11 EER23667.1 - 2.9 8.2 5.5 46 4.3 4.7 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HEAT PF02985.22 EER23668.1 - 5.4e-18 63.5 3.3 0.00013 21.9 0.0 9.1 10 0 0 10 10 8 3 HEAT repeat HEAT_2 PF13646.6 EER23668.1 - 4.2e-16 59.1 6.8 4.8e-05 23.7 0.0 7.8 5 3 4 9 9 9 5 HEAT repeats HEAT_EZ PF13513.6 EER23668.1 - 6.1e-16 58.6 11.6 5.7e-08 33.1 0.0 9.7 8 3 4 12 12 12 2 HEAT-like repeat Cnd1 PF12717.7 EER23668.1 - 4.6e-11 43.0 0.3 0.08 13.0 0.0 5.8 3 2 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EER23668.1 - 4.8e-11 42.4 3.2 3.7e-10 39.6 0.5 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EER23668.1 - 6.6e-10 39.5 0.1 0.18 12.4 0.0 6.6 6 2 1 7 7 6 2 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EER23668.1 - 4.6e-07 30.1 0.9 0.0059 16.8 0.2 3.5 3 0 0 3 3 3 2 Parkin co-regulated protein RTP1_C1 PF10363.9 EER23668.1 - 3.6e-06 27.1 1.1 0.73 10.0 0.0 5.4 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EER23668.1 - 7.1e-06 25.7 0.0 0.011 15.3 0.0 3.4 2 1 1 3 3 3 2 CLASP N terminal MMS19_C PF12460.8 EER23668.1 - 2.2e-05 23.8 3.2 0.00023 20.4 0.0 3.2 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal UME PF08064.13 EER23668.1 - 0.00023 21.0 0.2 1.8 8.5 0.0 5.3 4 2 2 6 6 6 1 UME (NUC010) domain RIX1 PF08167.12 EER23668.1 - 0.012 15.4 0.0 0.4 10.4 0.0 3.1 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.23 EER23668.1 - 0.045 13.8 0.1 43 4.4 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat UNC45-central PF11701.8 EER23668.1 - 0.11 12.4 0.1 1.5 8.8 0.1 2.9 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central NPC1_N PF16414.5 EER23669.1 - 3e-84 282.4 4.8 4.3e-84 281.9 4.8 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EER23669.1 - 6e-77 259.5 13.1 1.1e-50 172.6 0.1 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.8 EER23669.1 - 1.2e-52 177.9 7.1 1.2e-52 177.9 7.1 3.1 2 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EER23669.1 - 1.4e-07 30.8 7.7 1.4e-07 30.8 7.7 3.3 3 0 0 3 3 3 1 MMPL family Folate_rec PF03024.14 EER23669.1 - 0.00071 19.5 2.5 0.0014 18.5 2.5 1.4 1 0 0 1 1 1 1 Folate receptor family REV1_C PF16727.5 EER23669.1 - 0.046 14.1 0.3 0.11 13.0 0.3 1.5 1 0 0 1 1 1 0 DNA repair protein REV1 C-terminal domain PIRT PF15099.6 EER23669.1 - 8.7 5.9 6.2 20 4.8 0.0 3.3 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family DUF2433 PF10360.9 EER23670.1 - 4.1e-49 165.8 0.0 6.5e-49 165.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 EER23670.1 - 0.0017 18.6 0.0 0.0064 16.7 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EER23670.1 - 0.0017 18.9 0.0 0.0034 17.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase API5 PF05918.11 EER23670.1 - 3.1 6.5 4.7 4.8 5.9 4.7 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PAP1 PF08601.10 EER23671.1 - 1.6e-114 383.6 21.7 1.6e-114 383.6 21.7 2.3 1 1 1 2 2 2 2 Transcription factor PAP1 bZIP_1 PF00170.21 EER23671.1 - 4.8e-08 33.0 11.5 1.2e-07 31.7 11.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 EER23671.1 - 0.016 15.8 0.3 0.041 14.5 0.3 1.7 1 0 0 1 1 1 0 SlyX SHE3 PF17078.5 EER23671.1 - 0.065 13.0 4.7 0.11 12.1 4.7 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 TolA_bind_tri PF16331.5 EER23671.1 - 0.1 12.7 2.6 0.29 11.2 2.6 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation DUF16 PF01519.16 EER23671.1 - 0.11 12.9 2.4 0.1 13.1 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 dsrm PF00035.26 EER23671.1 - 0.11 13.2 0.9 0.4 11.4 0.9 1.9 1 0 0 1 1 1 0 Double-stranded RNA binding motif CDC45 PF02724.14 EER23671.1 - 2.6 6.3 8.2 4.8 5.4 8.2 1.3 1 0 0 1 1 1 0 CDC45-like protein bZIP_Maf PF03131.17 EER23671.1 - 8.9 6.9 17.2 0.18 12.3 10.0 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor Tudor_3 PF18115.1 EER23672.1 - 1.5e-07 31.2 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EER23672.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.11 EER23672.1 - 0.0073 16.4 0.7 0.027 14.6 0.1 2.1 2 0 0 2 2 2 1 SGF29 tudor-like domain FAM220 PF15487.6 EER23672.1 - 0.032 13.9 0.4 0.056 13.1 0.4 1.4 1 0 0 1 1 1 0 FAM220 family LBR_tudor PF09465.10 EER23672.1 - 0.04 13.7 0.0 0.073 12.9 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF2730 PF10805.8 EER23672.1 - 0.069 13.3 1.1 0.11 12.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) TRAUB PF08164.12 EER23673.1 - 2.2e-30 105.0 0.0 7.4e-30 103.3 0.0 2.0 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EER23673.1 - 1.9e-29 103.1 0.3 1.9e-29 103.1 0.3 2.9 4 1 0 4 4 4 1 Apoptosis antagonizing transcription factor LZ_Tnp_IS66 PF13007.7 EER23673.1 - 8.3 7.3 16.8 6.5 7.6 0.1 4.7 3 1 0 3 3 3 0 Transposase C of IS166 homeodomain ParA PF10609.9 EER23674.1 - 1.3e-77 260.6 0.1 4.4e-68 229.4 0.0 3.8 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EER23674.1 - 3.1e-07 30.5 0.2 0.28 11.2 0.5 3.2 3 0 0 3 3 3 3 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EER23674.1 - 0.00012 22.0 2.0 0.039 13.9 0.6 3.1 3 0 0 3 3 3 2 AAA domain MipZ PF09140.11 EER23674.1 - 0.13 11.5 0.1 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 ATPase MipZ Abhydrolase_3 PF07859.13 EER23675.1 - 5.9e-28 98.2 0.0 9.3e-18 64.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EER23675.1 - 1.7e-10 40.3 0.0 5.1e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Steryl acetyl hydrolase WGG PF10273.9 EER23676.1 - 8.9e-31 106.4 0.3 1.4e-30 105.7 0.3 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 PDDEXK_10 PF07788.11 EER23676.1 - 0.025 14.5 0.1 0.046 13.7 0.1 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily RRP7 PF12923.7 EER23676.1 - 0.3 11.2 3.5 0.95 9.6 3.5 1.9 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain GTP_EFTU PF00009.27 EER23677.1 - 1.1e-41 142.5 0.0 2e-41 141.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EER23677.1 - 1.1e-28 99.7 0.0 2.8e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EER23677.1 - 1.2e-09 38.5 0.3 2.8e-09 37.2 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Hamartin PF04388.12 EER23677.1 - 0.00025 19.9 12.0 0.00032 19.5 12.0 1.1 1 0 0 1 1 1 1 Hamartin protein MMR_HSR1 PF01926.23 EER23677.1 - 0.039 14.0 0.0 0.13 12.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP-alpha_N PF04086.13 EER23677.1 - 0.088 12.7 18.2 0.058 13.3 16.5 1.6 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Mcm10 PF09332.11 EER23677.1 - 0.59 9.5 12.2 0.9 8.9 12.2 1.2 1 0 0 1 1 1 0 Mcm10 replication factor CDC27 PF09507.10 EER23677.1 - 2.4 7.4 22.6 3.7 6.8 22.6 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ran-binding PF05508.11 EER23678.1 - 1.4e-119 398.7 1.0 1.8e-119 398.3 1.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BSD PF03909.17 EER23679.1 - 1.4e-19 69.8 1.2 2.6e-19 69.0 1.2 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 EER23679.1 - 0.0041 17.1 3.1 0.0067 16.4 3.1 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_2 PF07719.17 EER23679.1 - 1.4 9.2 3.6 2.7 8.3 0.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Lyase_1 PF00206.20 EER23681.1 - 1.2e-89 300.8 0.0 1.7e-89 300.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EER23681.1 - 4.2e-23 81.9 0.0 1.1e-22 80.5 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1451 PF07295.11 EER23681.1 - 0.14 12.2 0.1 0.5 10.4 0.0 2.0 2 0 0 2 2 2 0 Zinc-ribbon containing domain Rad4 PF03835.15 EER23682.1 - 5.4e-37 126.7 0.0 1.3e-36 125.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EER23682.1 - 5e-26 90.9 0.1 1.2e-25 89.7 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EER23682.1 - 4.3e-21 74.5 0.0 9.8e-21 73.3 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EER23682.1 - 1.4e-16 61.2 1.2 8.2e-16 58.7 0.1 2.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EER23682.1 - 0.00011 22.6 0.0 0.00059 20.3 0.0 2.3 1 1 0 1 1 1 1 Transglutaminase-like superfamily Filament PF00038.21 EER23683.1 - 0.0064 16.1 10.9 0.0064 16.1 10.9 8.1 1 1 7 8 8 8 5 Intermediate filament protein FAM184 PF15665.5 EER23683.1 - 0.0067 16.2 34.9 0.0067 16.2 34.9 6.9 1 1 6 7 7 7 2 Family with sequence similarity 184, A and B Spc7 PF08317.11 EER23683.1 - 0.19 10.6 173.9 0.41 9.5 16.2 8.3 1 1 8 9 9 9 0 Spc7 kinetochore protein PTPA PF03095.15 EER23685.1 - 1.3e-121 405.8 0.0 1.5e-121 405.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.13 EER23686.1 - 1.7e-62 212.0 1.6 2e-62 211.8 1.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Glyco_hydro_3_C PF01915.22 EER23687.1 - 1.9e-50 171.7 0.0 3.5e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EER23687.1 - 1.1e-41 143.2 0.0 1.7e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EER23687.1 - 6.2e-18 64.7 0.1 1.1e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PNP_UDP_1 PF01048.20 EER23689.1 - 2.4e-38 131.7 0.1 2.9e-38 131.4 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily BUD22 PF09073.10 EER23690.1 - 8.3e-96 322.0 22.4 1.7e-95 321.0 22.4 1.4 1 1 0 1 1 1 1 BUD22 Complex1_30kDa PF00329.19 EER23692.1 - 6.9e-45 152.6 0.0 9.6e-45 152.2 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 EER23693.1 - 2.6e-19 68.8 13.3 4.3e-19 68.0 13.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EER23693.1 - 4.9e-06 26.3 8.4 8.4e-06 25.6 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EER23693.1 - 1.6e-05 24.6 0.0 3.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 EER23693.1 - 0.001 19.4 11.6 0.0019 18.5 11.6 1.5 1 0 0 1 1 1 1 Ring finger domain Baculo_IE-1 PF05290.11 EER23693.1 - 0.0033 17.4 4.4 0.0065 16.4 4.4 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 EER23693.1 - 0.006 16.0 2.0 0.006 16.0 2.0 3.5 4 1 0 4 4 3 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 EER23693.1 - 0.2 11.5 9.5 1.5 8.7 9.7 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EER23693.1 - 0.23 11.4 12.7 0.46 10.4 12.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 EER23693.1 - 0.48 10.6 5.2 1 9.6 5.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.7 EER23693.1 - 3.3 7.8 9.3 20 5.3 9.9 2.0 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.6 EER23693.1 - 5.2 7.2 10.8 11 6.1 10.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger E1_dh PF00676.20 EER23694.1 - 7.2e-90 301.0 0.3 8.8e-90 300.7 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EER23694.1 - 3.5e-05 23.6 0.1 0.00038 20.3 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 EER23694.1 - 0.0034 16.2 0.0 0.0061 15.4 0.0 1.4 1 0 0 1 1 1 1 XFP N-terminal domain DXP_synthase_N PF13292.6 EER23694.1 - 0.053 12.7 0.0 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase Ubie_methyltran PF01209.18 EER23695.1 - 1.9e-79 266.2 0.0 2.6e-79 265.9 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EER23695.1 - 1e-15 58.2 0.0 3.6e-15 56.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER23695.1 - 5.1e-15 55.9 0.0 3.7e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER23695.1 - 1.8e-12 47.3 0.0 3.8e-12 46.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER23695.1 - 3e-09 37.5 0.0 4.7e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER23695.1 - 2.7e-07 30.6 0.0 4.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EER23695.1 - 0.027 14.3 0.0 0.16 11.8 0.0 2.1 2 1 0 3 3 3 0 Hypothetical methyltransferase Cytomega_TRL10 PF06084.11 EER23696.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF4120 PF13496.6 EER23696.1 - 0.15 12.5 0.2 1.7 9.0 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4120) SIS PF01380.22 EER23697.1 - 1.3e-10 41.2 0.0 3.1e-10 40.0 0.0 1.6 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.6 EER23697.1 - 0.00026 21.0 0.0 0.0006 19.8 0.0 1.6 1 1 0 1 1 1 1 SIS domain BTB PF00651.31 EER23698.1 - 0.00073 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MutS_III PF05192.18 EER23699.1 - 0.00041 20.6 0.1 0.0018 18.5 0.0 2.2 3 0 0 3 3 3 1 MutS domain III RVT_1 PF00078.27 EER23699.1 - 0.016 14.8 0.1 0.049 13.1 0.1 1.9 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) 7TMR-HDED PF07697.11 EER23699.1 - 0.13 12.4 7.0 0.72 9.9 5.9 2.2 2 0 0 2 2 2 0 7TM-HD extracellular DUF5024 PF16427.5 EER23699.1 - 0.14 12.5 0.6 0.37 11.2 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) HAD PF12710.7 EER23700.1 - 4e-24 86.0 0.0 7.4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EER23700.1 - 0.0019 17.7 0.0 0.87 8.9 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.12 EER23700.1 - 0.0055 16.2 0.0 0.02 14.4 0.0 2.0 1 1 2 3 3 3 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EER23700.1 - 0.13 12.5 0.3 6.9 6.9 0.0 2.8 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase CTP_transf_like PF01467.26 EER23701.1 - 1.7e-24 86.6 0.0 2.4e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase-like HECT PF00632.25 EER23702.1 - 6.4e-76 255.8 0.0 1.9e-75 254.2 0.0 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Adaptin_N PF01602.20 EER23702.1 - 0.0052 15.4 1.4 0.02 13.4 0.0 2.3 2 0 0 2 2 2 1 Adaptin N terminal region HEAT PF02985.22 EER23702.1 - 0.036 14.3 0.2 6 7.4 0.1 3.6 2 0 0 2 2 2 0 HEAT repeat Arm PF00514.23 EER23702.1 - 4.2 7.6 13.9 35 4.6 0.1 6.5 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat eIF3_subunit PF08597.10 EER23703.1 - 0.01 15.7 5.6 0.01 15.7 5.6 2.2 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit CCDC71L PF15374.6 EER23703.1 - 5.4 6.2 13.6 8.8 5.5 13.6 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L Gpi16 PF04113.14 EER23704.1 - 6.7e-241 800.6 0.0 9.1e-241 800.2 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 EER23705.1 - 3.3e-74 249.7 0.3 4e-74 249.4 0.3 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 EER23705.1 - 0.00032 19.9 1.5 0.0006 19.0 0.5 1.7 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) T4SS PF07996.11 EER23705.1 - 0.018 15.5 0.6 0.044 14.2 0.1 1.8 2 0 0 2 2 2 0 Type IV secretion system proteins Glutaredoxin2_C PF04399.13 EER23705.1 - 0.14 12.0 0.0 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain MCPsignal PF00015.21 EER23705.1 - 0.16 11.8 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PIN_8 PF18476.1 EER23705.1 - 0.23 11.3 1.8 0.45 10.3 0.2 1.9 1 1 1 2 2 2 0 PIN like domain GRP PF07172.11 EER23705.1 - 0.5 11.1 23.0 0.46 11.2 21.4 1.8 2 0 0 2 2 2 0 Glycine rich protein family SPOC PF07744.13 EER23706.1 - 2.8e-24 85.7 0.0 5.6e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 EER23706.1 - 1.4e-23 83.5 0.0 2.8e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EER23706.1 - 3.5e-10 39.6 12.3 6.1e-10 38.8 12.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 EER23706.1 - 0.013 15.8 1.1 0.013 15.8 1.1 2.9 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 EER23706.1 - 0.056 13.0 5.2 0.099 12.2 5.2 1.4 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_10 PF10058.9 EER23706.1 - 1.4 8.7 6.6 2.5 7.9 6.6 1.4 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein OmpH PF03938.14 EER23707.1 - 0.019 15.3 6.2 0.019 15.3 6.2 2.3 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.6 EER23707.1 - 0.27 11.4 16.4 0.021 15.0 8.5 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF573 PF04504.14 EER23707.1 - 0.68 10.6 4.9 0.34 11.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF573 DUF3381 PF11861.8 EER23707.1 - 1.7 8.4 21.6 2 8.2 12.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) DUF2992 PF11208.8 EER23707.1 - 6 7.1 13.1 0.12 12.6 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) FF PF01846.19 EER23708.1 - 4.6e-14 52.3 10.5 1.7e-10 40.9 0.2 3.6 3 0 0 3 3 3 2 FF domain WW PF00397.26 EER23708.1 - 3.2e-09 36.7 0.8 3.2e-09 36.7 0.8 2.8 3 0 0 3 3 3 1 WW domain VGLL4 PF15245.6 EER23708.1 - 0.2 11.7 3.2 0.44 10.6 3.2 1.7 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Proteasome PF00227.26 EER23709.1 - 1.7e-61 207.0 0.2 2.1e-61 206.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EER23709.1 - 4.3e-13 48.7 0.1 8.7e-13 47.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EER23709.1 - 0.016 15.3 0.2 0.049 13.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EER23709.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit TMF_TATA_bd PF12325.8 EER23710.1 - 0.048 13.9 1.6 0.3 11.3 0.6 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 EER23710.1 - 0.1 11.9 1.4 0.12 11.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NAD_binding_10 PF13460.6 EER23712.1 - 9.9e-07 28.8 0.0 2.7e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EER23712.1 - 4.8e-05 23.8 0.0 0.002 18.5 0.0 2.3 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EER23712.1 - 9.8e-05 22.0 0.0 0.00028 20.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family HIM1 PF08732.10 EER23712.1 - 0.0004 19.9 0.0 0.00059 19.4 0.0 1.1 1 0 0 1 1 1 1 HIM1 KR PF08659.10 EER23712.1 - 0.094 12.6 0.0 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 KR domain DUF1471 PF07338.13 EER23712.1 - 0.1 12.6 0.2 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) FAM47 PF14642.6 EER23712.1 - 0.11 12.1 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 FAM47 family NAD_binding_4 PF07993.12 EER23712.1 - 0.15 11.2 0.0 0.94 8.6 0.0 2.1 2 1 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 EER23712.1 - 0.16 11.4 0.0 0.37 10.2 0.0 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_1 PF00667.20 EER23713.1 - 1.2e-67 227.7 0.0 1.9e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 EER23713.1 - 6.7e-12 45.8 0.0 1.8e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 EER23713.1 - 1.1e-09 38.9 0.0 2.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 EER23713.1 - 2.2e-05 24.7 0.1 6.1e-05 23.3 0.1 1.7 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II FAD_binding_6 PF00970.24 EER23713.1 - 0.028 14.8 0.0 0.28 11.5 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Transketolase_C PF02780.20 EER23713.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain POR_N PF01855.19 EER23713.1 - 0.16 11.7 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg FtsJ PF01728.19 EER23714.1 - 1.3e-63 214.3 0.0 1.8e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 EER23715.1 - 1.1e-41 142.5 0.0 2.4e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER23715.1 - 8.7e-27 93.7 0.1 1.4e-25 89.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER23715.1 - 0.00095 19.2 0.0 0.0029 17.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EER23715.1 - 0.029 14.7 1.3 0.061 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain FMO-like PF00743.19 EER23716.1 - 5.3e-14 51.5 0.2 6.4e-10 38.1 0.0 2.9 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EER23716.1 - 2.3e-11 43.5 0.0 8.2e-06 25.3 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER23716.1 - 1.8e-09 37.3 0.0 9.6e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER23716.1 - 4.8e-07 29.2 0.0 0.00023 20.4 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EER23716.1 - 2.1e-06 27.9 0.0 7.1e-06 26.2 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER23716.1 - 0.00026 20.7 0.0 0.15 11.6 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EER23716.1 - 0.0013 18.7 0.1 4.3 7.3 0.0 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.17 EER23716.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EER23716.1 - 0.042 12.9 0.0 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 EER23716.1 - 0.044 12.5 0.0 0.69 8.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.20 EER23716.1 - 0.092 12.8 0.0 5.2 7.1 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.18 EER23717.1 - 1.4e-20 73.4 0.0 2.3e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain VHS PF00790.19 EER23718.1 - 3.5e-26 91.7 0.0 9.2e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 EER23718.1 - 7e-06 26.3 0.6 1.6e-05 25.1 0.6 1.7 1 0 0 1 1 1 1 GAT domain ENTH PF01417.20 EER23718.1 - 7.8e-05 22.7 0.0 0.00086 19.3 0.0 2.2 2 0 0 2 2 2 1 ENTH domain REGB_T4 PF10715.9 EER23718.1 - 0.045 14.0 0.1 0.074 13.3 0.1 1.4 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB Inositol_P PF00459.25 EER23719.1 - 1.7e-54 185.2 0.3 4e-54 183.9 0.3 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.23 EER23720.1 - 2.6e-20 72.9 0.0 5e-10 39.9 0.0 2.5 2 1 0 2 2 2 2 Ribosomal protein L6 Tht1 PF04163.12 EER23721.1 - 3.3e-08 32.8 1.9 4.1e-07 29.2 1.9 2.0 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Pept_tRNA_hydro PF01195.19 EER23722.1 - 5.9e-24 84.9 0.0 5e-17 62.4 0.0 2.9 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase Aminotran_1_2 PF00155.21 EER23723.1 - 3.4e-37 128.5 0.0 3.8e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.19 EER23723.1 - 0.00038 19.2 0.0 0.00055 18.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.19 EER23723.1 - 0.00046 19.3 0.0 0.12 11.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EER23723.1 - 0.1 11.1 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EER23724.1 - 1.3e-37 129.4 0.0 2.9e-19 69.0 0.0 3.4 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EER23724.1 - 1.4e-19 70.7 0.0 3e-19 69.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain BATS PF06968.13 EER23725.1 - 9.9e-22 76.9 0.1 4e-21 74.9 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EER23725.1 - 1.2e-15 58.3 0.1 3.4e-15 56.8 0.1 1.8 2 0 0 2 2 2 1 Radical SAM superfamily DUF4630 PF15443.6 EER23725.1 - 0.1 12.7 0.1 0.31 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Oxidored_FMN PF00724.20 EER23726.1 - 1.1e-58 199.2 0.0 1.5e-58 198.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EER23726.1 - 0.0017 17.5 0.1 0.0033 16.6 0.0 1.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) GST_N_2 PF13409.6 EER23727.1 - 7.2e-10 39.0 0.1 3.3e-09 36.9 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EER23727.1 - 7.5e-09 35.9 0.0 1.2e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EER23727.1 - 3.3e-07 30.4 0.0 6.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EER23727.1 - 4.3e-07 30.1 0.0 8.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EER23727.1 - 7.4e-06 26.2 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EER23727.1 - 0.00017 21.5 0.1 0.00033 20.6 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.18 EER23728.1 - 1.1e-52 178.9 0.0 1.5e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EER23728.1 - 2.1e-31 108.2 0.0 3.5e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.13 EER23729.1 - 1.1e-207 689.8 0.0 1.3e-207 689.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAM104 PF15434.6 EER23730.1 - 0.017 15.7 1.6 0.1 13.1 0.1 2.3 2 0 0 2 2 2 0 Family 104 TPR_17 PF13431.6 EER23730.1 - 0.019 15.3 0.3 0.65 10.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SusD-like_3 PF14322.6 EER23730.1 - 0.13 12.6 2.2 0.23 11.8 0.9 2.0 1 1 1 2 2 2 0 Starch-binding associating with outer membrane Glyoxalase PF00903.25 EER23731.1 - 3.9e-21 75.6 0.6 3.9e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EER23731.1 - 1.1e-11 45.0 0.3 0.0002 21.6 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EER23731.1 - 1.3e-05 25.4 0.3 0.0003 21.0 0.3 2.6 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EER23731.1 - 0.00013 22.1 0.1 0.2 11.7 0.3 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain DUF4844 PF16133.5 EER23731.1 - 0.0022 18.5 0.2 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4844) COX15-CtaA PF02628.15 EER23732.1 - 1.3e-115 385.9 5.0 1.6e-115 385.6 5.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PQ-loop PF04193.14 EER23732.1 - 0.29 10.9 3.4 5.5 6.8 0.1 3.0 3 0 0 3 3 3 0 PQ loop repeat zf-RanBP PF00641.18 EER23733.1 - 0.042 13.2 3.1 0.082 12.2 3.1 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Prok-RING_2 PF14445.6 EER23733.1 - 0.089 13.0 8.1 0.21 11.8 8.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 tRNA-synt_2 PF00152.20 EER23734.1 - 1.5e-78 264.1 0.3 2.4e-78 263.4 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EER23734.1 - 7.8e-12 45.0 0.0 3.5e-11 42.9 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EER23734.1 - 1.4e-05 24.7 0.0 0.012 15.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) UCR_Fe-S_N PF10399.9 EER23734.1 - 0.77 9.2 4.4 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAF4 PF05236.14 EER23734.1 - 8.5 6.0 11.6 32 4.1 11.3 2.0 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Dynamin_N PF00350.23 EER23735.1 - 4.1e-26 92.0 0.0 2.4e-25 89.5 0.0 2.3 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EER23735.1 - 2.5e-19 69.6 0.0 1.4e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EER23735.1 - 0.0016 18.5 0.0 0.013 15.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EER23735.1 - 0.0036 17.4 0.2 0.014 15.6 0.2 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_16 PF13191.6 EER23735.1 - 0.047 14.1 0.0 0.17 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EER23735.1 - 0.058 13.6 0.7 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Surfac_D-trimer PF09006.11 EER23735.1 - 0.077 12.9 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation IIGP PF05049.13 EER23735.1 - 0.094 11.8 0.1 4.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) CDH1_2_SANT_HL1 PF18375.1 EER23735.1 - 0.27 11.9 1.8 1.8 9.3 1.3 2.4 2 0 0 2 2 2 0 CDH1/2 SANT-Helical linker 1 NTP_transferase PF00483.23 EER23736.1 - 1.2e-30 106.9 0.0 1.6e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EER23736.1 - 9.1e-08 32.6 0.0 1.4e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EER23736.1 - 2.4e-07 30.2 5.8 2.9e-05 23.6 0.0 3.5 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EER23736.1 - 0.017 14.1 0.2 2.4 7.0 0.1 2.1 2 0 0 2 2 2 0 L-fucokinase IspD PF01128.19 EER23736.1 - 0.019 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glycos_transf_2 PF00535.26 EER23736.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Bys1 PF04681.12 EER23737.1 - 9.2e-18 64.7 0.1 1.1e-17 64.4 0.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Amidohydro_2 PF04909.14 EER23739.1 - 8.3e-37 127.5 0.7 1.2e-36 127.0 0.7 1.2 1 0 0 1 1 1 1 Amidohydrolase Dioxygenase_C PF00775.21 EER23740.1 - 4.5e-47 159.8 0.0 6e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EER23740.1 - 7.4e-29 99.4 0.1 1.1e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EER23740.1 - 1.8e-06 28.1 0.0 4.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EER23740.1 - 0.013 15.5 0.0 4.8 7.3 0.0 3.1 3 0 0 3 3 3 0 CarboxypepD_reg-like domain MFS_1 PF07690.16 EER23741.1 - 9.8e-33 113.5 36.2 1.4e-32 113.1 36.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Hydrolase_4 PF12146.8 EER23742.1 - 2.4e-22 79.4 0.0 3.5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EER23742.1 - 2.1e-21 76.7 0.1 1.4e-17 64.2 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER23742.1 - 5.2e-19 69.7 0.0 8.3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EER23742.1 - 1.3e-06 28.7 0.0 8.7e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase2 PF12740.7 EER23742.1 - 3.4e-06 26.2 0.2 6.6e-06 25.2 0.2 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 EER23742.1 - 1.4e-05 24.9 0.3 3e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 PGAP1-like protein DLH PF01738.18 EER23742.1 - 1.6e-05 24.6 0.0 0.088 12.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EER23742.1 - 4.3e-05 23.3 0.1 9.1e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EER23742.1 - 0.00014 21.8 0.1 0.0006 19.7 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_8 PF06259.12 EER23742.1 - 0.004 16.8 0.5 0.01 15.5 0.3 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase Abhydrolase_3 PF07859.13 EER23742.1 - 0.0044 16.9 0.1 0.0058 16.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EER23742.1 - 0.0055 16.5 0.0 12 5.6 0.0 3.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF1057 PF06342.12 EER23742.1 - 0.0065 15.5 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) BAAT_C PF08840.11 EER23742.1 - 0.0068 16.3 0.0 0.029 14.3 0.0 1.9 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.11 EER23742.1 - 0.013 14.5 0.3 0.022 13.8 0.3 1.3 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S9 PF00326.21 EER23742.1 - 0.031 13.7 0.0 3.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 EER23742.1 - 0.048 13.8 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Lipase_3 PF01764.25 EER23742.1 - 0.076 12.9 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 EER23742.1 - 0.089 11.3 3.1 1.7 7.1 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II FSH1 PF03959.13 EER23742.1 - 0.094 12.4 0.0 1.8 8.2 0.0 2.6 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Esterase PF00756.20 EER23742.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF3530 PF12048.8 EER23742.1 - 0.19 11.1 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Fungal_trans PF04082.18 EER23743.1 - 4.2e-23 81.7 0.1 7e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER23743.1 - 6.9e-08 32.5 6.5 1.2e-07 31.8 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.17 EER23744.1 - 7.5e-42 143.7 0.0 3.6e-40 138.2 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Putative_PNPOx PF01243.20 EER23745.1 - 1.2e-09 38.2 0.0 0.00058 20.0 0.0 2.6 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.24 EER23745.1 - 0.00012 22.3 0.0 0.0026 18.1 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EER23745.1 - 0.11 13.2 0.0 0.41 11.3 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain zf-RING_2 PF13639.6 EER23746.1 - 5.2e-05 23.5 0.1 0.00011 22.5 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EER23746.1 - 5.9e-05 23.3 2.4 8.6e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EER23746.1 - 0.17 11.7 0.3 0.35 10.8 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EER23746.1 - 0.19 11.8 0.3 0.38 10.8 0.0 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Atx10homo_assoc PF09759.9 EER23747.1 - 3.3e-31 107.2 0.5 7e-31 106.2 0.1 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DHHC PF01529.20 EER23748.1 - 0.0011 19.1 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Myb_DNA-bind_2 PF08914.11 EER23749.1 - 1.3e-22 79.7 0.6 1.5e-20 73.1 0.2 2.6 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.8 EER23749.1 - 2.8e-19 69.0 0.0 7.7e-18 64.4 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Rap1-DNA-bind PF09197.10 EER23749.1 - 2.5e-10 40.9 3.3 2.9e-05 24.6 0.2 3.1 1 1 1 3 3 3 2 Rap1, DNA-binding BRCT_2 PF16589.5 EER23749.1 - 4.5e-09 36.6 0.0 1.3e-08 35.1 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain MAT1 PF06391.13 EER23749.1 - 0.034 14.0 0.9 0.084 12.7 0.9 1.7 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 LUC7 PF03194.15 EER23749.1 - 0.051 13.2 0.6 0.12 12.0 0.6 1.5 1 0 0 1 1 1 0 LUC7 N_terminus Inhibitor_I68 PF10468.9 EER23749.1 - 0.085 13.3 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 DUF4404 PF14357.6 EER23749.1 - 1.9 9.2 7.4 0.8 10.4 1.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Chromo_shadow PF01393.19 EER23750.1 - 2.5e-22 78.7 1.8 1.7e-18 66.4 0.5 2.2 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EER23750.1 - 9.8e-13 47.8 0.0 2.9e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cpn60_TCP1 PF00118.24 EER23751.1 - 2.2e-158 527.9 2.5 2.5e-158 527.7 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.21 EER23751.1 - 0.12 12.5 0.5 0.73 9.9 0.1 2.3 2 0 0 2 2 2 0 Resolvase, N terminal domain Enolase_N PF03952.16 EER23751.1 - 1.2 9.3 4.4 3.6 7.8 0.1 2.9 3 0 0 3 3 3 0 Enolase, N-terminal domain Ank_2 PF12796.7 EER23752.1 - 8.7e-35 119.2 1.7 2.4e-11 44.0 0.0 9.2 8 3 2 10 10 10 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER23752.1 - 1.4e-30 104.9 0.9 0.0016 18.7 0.0 9.5 8 1 1 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EER23752.1 - 2.6e-25 88.4 2.2 0.0007 20.1 0.0 11.0 9 2 2 11 11 11 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER23752.1 - 9.3e-24 80.9 9.3 0.0032 17.8 0.0 10.8 13 0 0 13 13 13 7 Ankyrin repeat Ank PF00023.30 EER23752.1 - 1.2e-14 54.0 12.9 0.033 14.7 0.0 8.9 7 1 1 8 8 8 4 Ankyrin repeat YfkD PF14167.6 EER23752.1 - 0.044 13.0 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 YfkD-like protein Phage_T7_Capsid PF05396.11 EER23752.1 - 0.049 14.0 3.9 0.47 10.8 0.1 3.8 4 1 2 6 6 6 0 Phage T7 capsid assembly protein CRISPR_Cse1 PF09481.10 EER23752.1 - 0.37 9.8 2.7 0.68 9.0 2.7 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF3295 PF11702.8 EER23753.1 - 1.8e-182 608.1 38.3 2.1e-182 607.9 38.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EER23753.1 - 6.7e-12 45.0 3.2 1.4e-11 44.0 3.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Shikimate_DH PF01488.20 EER23754.1 - 0.0078 16.3 0.1 0.059 13.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AvrM_N PF18247.1 EER23754.1 - 0.046 13.7 0.2 0.089 12.7 0.2 1.5 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain FMO-like PF00743.19 EER23754.1 - 0.093 11.1 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EER23754.1 - 1 8.5 3.7 6.9 5.8 0.1 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-C3HC PF07967.13 EER23755.1 - 1.2e-38 132.2 1.6 1.5e-36 125.4 0.1 2.6 2 1 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EER23755.1 - 8.9e-32 109.1 0.6 3.5e-29 100.8 0.1 2.8 3 0 0 3 3 3 2 Rsm1-like Pox_MCEL PF03291.16 EER23756.1 - 2.8e-55 187.7 0.0 1e-52 179.3 0.0 3.2 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EER23756.1 - 3.9e-10 40.3 0.0 5.1e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EER23756.1 - 8.1e-09 36.1 0.0 4e-08 33.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER23756.1 - 1.3e-06 28.9 0.0 0.087 13.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EER23756.1 - 9.2e-06 25.5 0.0 0.00011 22.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER23756.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EER23756.1 - 0.0022 17.3 0.0 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Sulfate_transp PF00916.20 EER23757.1 - 1.7e-111 372.6 17.0 2.5e-111 372.1 17.0 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EER23757.1 - 4.2e-08 32.8 0.0 8.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EER23757.1 - 0.0088 16.4 3.5 0.0088 16.4 3.5 3.4 2 2 1 3 3 3 1 Molybdate transporter of MFS superfamily zf-Nse PF11789.8 EER23758.1 - 1.5e-22 79.2 1.1 2.7e-22 78.3 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EER23758.1 - 0.00048 20.1 0.5 0.0012 18.8 0.1 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EER23758.1 - 0.0053 16.6 1.8 0.025 14.4 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EER23758.1 - 0.009 15.7 1.9 0.11 12.3 0.3 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.25 EER23758.1 - 0.16 11.8 0.9 0.66 9.9 0.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1178 PF06676.11 EER23758.1 - 0.23 11.9 4.8 0.11 12.9 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) DUF445 PF04286.12 EER23758.1 - 6.4 6.5 7.7 2.3 7.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Zn_clus PF00172.18 EER23759.1 - 3.7e-10 39.7 10.2 5.5e-10 39.2 10.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.18 EER23760.1 - 6.5e-22 76.7 3.4 6.5e-22 76.7 3.4 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain PEX11 PF05648.14 EER23761.1 - 4.8e-68 229.0 1.1 5.7e-68 228.7 1.1 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.24 EER23762.1 - 1.9e-33 116.1 26.2 3.3e-22 79.0 7.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EER23762.1 - 4.2e-15 55.5 38.0 4.2e-15 55.5 38.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Transgly_assoc PF04226.13 EER23762.1 - 1 9.7 0.0 1 9.7 0.0 4.2 4 0 0 4 4 4 0 Transglycosylase associated protein RPN7 PF10602.9 EER23763.1 - 2.5e-56 190.1 0.1 4e-56 189.4 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EER23763.1 - 2e-12 47.6 0.0 3.3e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 EER23763.1 - 0.064 13.3 0.6 0.25 11.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fur_reg_FbpB PF13040.6 EER23763.1 - 0.42 10.2 2.0 0.7 9.5 0.2 2.1 2 0 0 2 2 2 0 Fur-regulated basic protein B Aminotran_1_2 PF00155.21 EER23764.1 - 1.3e-38 133.2 0.0 1.8e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PEPCK_ATP PF01293.20 EER23765.1 - 2.4e-217 722.2 0.0 2.9e-217 721.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 EER23765.1 - 0.035 14.5 0.0 0.068 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EER23765.1 - 0.15 12.2 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 EER23766.1 - 1.7e-55 185.0 2.1 1.7e-18 66.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Meiotic_rec114 PF03525.14 EER23767.1 - 7.8e-07 28.4 5.2 5.2e-05 22.4 0.0 2.5 2 1 0 2 2 2 2 Meiotic recombination protein rec114 GPI-anchored PF10342.9 EER23769.1 - 6.9e-16 58.8 0.6 6.9e-16 58.8 0.6 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Atrophin-1 PF03154.15 EER23769.1 - 0.025 12.9 9.7 0.025 12.9 9.7 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF1771 PF08590.10 EER23770.1 - 1.2e-10 41.6 6.4 4.4e-10 39.8 6.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.16 EER23770.1 - 2e-05 24.2 0.0 4.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain Smr PF01713.21 EER23770.1 - 0.15 12.5 0.3 0.53 10.7 0.2 2.1 2 1 0 2 2 2 0 Smr domain DMA PF03474.14 EER23770.1 - 0.19 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif SelR PF01641.18 EER23771.1 - 1.9e-51 173.2 0.2 2.2e-51 173.0 0.2 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EER23771.1 - 0.0023 17.6 0.2 0.24 11.1 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 EER23771.1 - 0.0065 16.5 2.0 0.57 10.2 0.1 2.4 2 1 0 2 2 2 2 Double zinc ribbon Yippee-Mis18 PF03226.14 EER23771.1 - 0.013 15.7 0.8 0.038 14.2 0.8 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MCM_OB PF17207.3 EER23771.1 - 0.065 13.1 0.3 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 MCM OB domain Ribosomal_L37e PF01907.19 EER23771.1 - 0.64 10.2 4.7 6 7.1 0.9 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e Zn_ribbon_recom PF13408.6 EER23771.1 - 3.8 8.1 7.1 7.7 7.1 0.6 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain BshC PF10079.9 EER23772.1 - 0.0066 15.3 3.0 0.0066 15.3 3.0 2.2 2 0 0 2 2 2 1 Bacillithiol biosynthesis BshC Apolipoprotein PF01442.18 EER23772.1 - 0.0074 16.2 4.4 0.0074 16.2 4.4 2.5 3 0 0 3 3 3 1 Apolipoprotein A1/A4/E domain Exonuc_VII_L PF02601.15 EER23772.1 - 0.034 13.7 0.4 0.034 13.7 0.4 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit Phasin PF05597.11 EER23772.1 - 0.063 13.3 4.8 0.29 11.2 1.1 2.7 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Lipoprotein_2 PF00921.17 EER23772.1 - 0.088 12.4 1.8 0.35 10.4 1.2 1.9 1 1 0 1 1 1 0 Borrelia lipoprotein DUF1664 PF07889.12 EER23772.1 - 0.16 12.0 1.6 0.48 10.5 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MtrG PF04210.13 EER23772.1 - 0.22 11.4 6.5 0.46 10.4 1.4 3.3 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G FliD_C PF07195.12 EER23772.1 - 0.39 10.1 4.0 0.21 11.0 1.2 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus YvrJ PF12841.7 EER23772.1 - 0.56 9.8 1.4 8.9 5.9 0.0 3.0 3 1 0 3 3 3 0 YvrJ protein family WSD PF15613.6 EER23772.1 - 0.65 10.5 4.4 0.28 11.7 1.0 2.2 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif GAS PF13851.6 EER23772.1 - 2.2 7.6 14.5 0.28 10.5 6.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 EER23772.1 - 3.9 7.8 10.8 0.58 10.5 0.5 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) Fib_alpha PF08702.10 EER23772.1 - 4.2 7.5 6.4 1.2 9.3 2.5 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family ArfGap PF01412.18 EER23773.1 - 5.4e-40 136.1 1.3 8.2e-40 135.5 1.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Synaptobrevin PF00957.21 EER23774.1 - 0.14 11.9 1.1 4.5 7.1 0.5 2.1 1 1 1 2 2 2 0 Synaptobrevin ArAE_2_N PF10337.9 EER23775.1 - 3.7e-29 102.1 15.5 1.2e-25 90.5 0.2 3.4 3 1 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EER23775.1 - 1.8e-15 57.2 17.4 1.8e-15 57.2 17.4 3.2 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EER23775.1 - 5e-11 42.9 0.0 5e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 ALMT PF11744.8 EER23775.1 - 0.0045 15.9 16.8 0.011 14.6 13.7 2.5 2 1 0 2 2 2 1 Aluminium activated malate transporter Zds_C PF08632.10 EER23776.1 - 2.2e-27 94.6 2.4 4.3e-27 93.6 2.4 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ysc84 PF04366.12 EER23777.1 - 8.8e-41 138.6 0.2 2e-40 137.5 0.2 1.6 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EER23777.1 - 2.6e-13 49.3 0.3 8e-13 47.8 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EER23777.1 - 1.2e-11 44.1 0.1 7.8e-11 41.5 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EER23777.1 - 1.4e-11 44.1 0.1 2.7e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain EF_assoc_2 PF08356.12 EER23778.1 - 3e-34 116.9 0.0 5.6e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EER23778.1 - 9.7e-31 105.2 0.4 1.7e-30 104.4 0.4 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EER23778.1 - 7.3e-24 84.2 0.0 1.2e-13 50.9 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EER23778.1 - 2e-12 47.4 0.0 2.9e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EER23778.1 - 6.7e-08 32.6 0.0 0.00014 21.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.6 EER23778.1 - 5.1e-06 26.9 1.0 0.0045 17.4 0.4 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EER23778.1 - 8.5e-06 25.0 2.1 0.1 12.2 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EER23778.1 - 1.1e-05 24.9 1.9 0.067 13.1 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_16 PF13191.6 EER23778.1 - 1.3e-05 25.6 0.1 0.089 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EER23778.1 - 2.7e-05 23.8 0.6 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 EER23778.1 - 0.00016 21.8 0.3 0.72 9.9 0.3 2.9 2 1 0 2 2 2 2 Dynamin family EF-hand_10 PF14788.6 EER23778.1 - 0.00085 19.1 1.5 0.22 11.4 0.2 2.5 2 0 0 2 2 2 1 EF hand AAA_22 PF13401.6 EER23778.1 - 0.002 18.4 0.3 1.4 9.2 0.0 2.7 2 1 1 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EER23778.1 - 0.0029 17.5 0.2 2.2 8.2 0.1 3.3 3 0 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 EER23778.1 - 0.0041 17.1 0.1 2.2 8.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.18 EER23778.1 - 0.0088 15.8 0.2 0.17 11.6 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EER23778.1 - 0.012 16.1 0.1 9.2 6.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 EER23778.1 - 0.027 14.9 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 EER23778.1 - 0.031 13.5 0.5 1.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EER23778.1 - 0.034 14.7 0.4 2.1 8.9 0.1 2.8 3 0 0 3 3 3 0 AAA domain GTP_EFTU PF00009.27 EER23778.1 - 0.04 13.5 0.1 20 4.6 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 EER23778.1 - 0.042 14.1 0.1 11 6.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EER23778.1 - 0.057 12.9 0.1 1.4 8.4 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EER23778.1 - 0.064 13.0 0.1 0.41 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 EER23778.1 - 0.066 12.5 0.0 0.75 9.0 0.0 2.3 2 0 0 2 2 2 0 Septin EF-hand_8 PF13833.6 EER23778.1 - 0.07 13.0 0.9 5.6 6.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair FtsK_SpoIIIE PF01580.18 EER23778.1 - 0.13 11.5 0.3 11 5.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EER23778.1 - 0.14 11.8 0.1 14 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EER23778.1 - 0.15 11.5 0.6 4 6.8 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain ATP_bind_1 PF03029.17 EER23778.1 - 0.24 11.2 1.3 35 4.0 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein IIGP PF05049.13 EER23778.1 - 0.26 10.3 0.8 0.96 8.4 0.2 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) WD40 PF00400.32 EER23779.1 - 1.6e-11 44.5 15.9 2.2e-05 25.1 0.4 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23779.1 - 3.4e-10 40.1 0.0 0.0042 17.4 0.1 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EER23779.1 - 0.00016 19.8 0.0 0.00071 17.7 0.0 1.7 1 1 1 2 2 2 1 IKI3 family PD40 PF07676.12 EER23779.1 - 0.0034 17.3 0.1 2.2 8.3 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EER23779.1 - 0.0086 16.0 0.0 0.031 14.2 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EER23779.1 - 0.044 12.3 0.0 0.14 10.7 0.0 1.8 2 0 0 2 2 2 0 Cytochrome D1 heme domain YpsA PF06908.11 EER23779.1 - 0.056 13.4 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family Arrestin_C PF02752.22 EER23780.1 - 5.1e-11 43.1 0.0 9.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EER23780.1 - 1.7e-07 31.4 0.0 3.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EER23780.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like ApoO PF09769.9 EER23781.1 - 0.045 13.7 0.9 4.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein O Mer2 PF09074.10 EER23781.1 - 0.42 10.4 6.3 1 9.2 5.8 1.9 2 0 0 2 2 2 0 Mer2 Exonuc_VII_L PF02601.15 EER23781.1 - 0.48 9.9 4.9 0.75 9.3 4.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit KxDL PF10241.9 EER23781.1 - 1.1 9.5 7.2 0.18 12.1 0.7 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein Glyoxalase PF00903.25 EER23782.1 - 2.6e-38 131.1 0.0 3.8e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EER23782.1 - 9e-16 58.1 0.0 3e-05 24.2 0.0 4.4 2 2 2 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EER23782.1 - 4.7e-06 27.4 0.0 0.037 14.8 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 EER23782.1 - 0.00021 21.5 0.0 0.28 11.3 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EER23782.1 - 0.0014 18.6 2.3 0.66 9.9 0.1 3.8 4 0 0 4 4 4 1 Glyoxalase-like domain MoaF PF10703.9 EER23782.1 - 0.032 14.2 0.0 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 MoaF N-terminal domain Fe-ADH PF00465.19 EER23784.1 - 1.9e-101 339.6 0.0 2.4e-101 339.2 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EER23784.1 - 4e-16 59.5 0.1 9.2e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EER23784.1 - 0.0066 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein 2-Hacid_dh_C PF02826.19 EER23785.1 - 2e-56 190.2 0.0 3.5e-56 189.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER23785.1 - 1.9e-36 124.7 0.2 3.7e-36 123.7 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EER23785.1 - 0.0024 17.2 2.5 0.0077 15.5 2.5 1.7 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 EER23785.1 - 0.024 15.2 0.0 0.066 13.7 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 EER23785.1 - 0.043 13.9 0.9 0.17 11.9 0.1 2.1 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EER23785.1 - 0.065 13.4 2.1 0.093 12.9 0.2 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase UCH_1 PF13423.6 EER23786.1 - 3.3e-98 329.2 3.4 5.5e-98 328.5 3.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EER23786.1 - 2.2e-13 51.1 0.0 1.5e-12 48.4 0.0 2.2 2 0 0 2 2 2 1 Exonuclease UCH PF00443.29 EER23786.1 - 0.00035 20.1 0.3 0.00065 19.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 EER23786.1 - 0.16 12.3 0.0 9.3 6.6 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain KH_1 PF00013.29 EER23787.1 - 1.2e-95 313.3 20.7 5e-14 51.9 0.0 13.4 14 1 0 14 14 14 10 KH domain SLS PF14611.6 EER23787.1 - 7.2e-12 45.6 4.7 0.084 12.7 0.0 6.9 5 2 2 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 EER23787.1 - 9.8e-12 44.5 14.8 0.0042 16.9 0.6 8.2 8 0 0 8 8 8 3 KH domain KH_4 PF13083.6 EER23787.1 - 0.00035 20.4 5.7 3.7 7.5 0.0 6.5 6 0 0 6 6 6 1 KH domain LPD5 PF18799.1 EER23787.1 - 0.53 10.7 2.7 33 4.9 0.4 3.0 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 Pkinase PF00069.25 EER23788.1 - 1.7e-72 244.0 0.0 2.6e-72 243.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23788.1 - 1e-45 156.1 0.0 1.6e-45 155.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EER23788.1 - 5e-21 74.8 0.1 1.3e-20 73.5 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EER23788.1 - 2.2e-07 30.5 0.0 4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EER23788.1 - 3.8e-07 29.2 0.7 1.6e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase DSHCT PF08148.12 EER23788.1 - 0.021 14.5 0.2 0.055 13.1 0.0 1.7 2 0 0 2 2 2 0 DSHCT (NUC185) domain Kdo PF06293.14 EER23788.1 - 0.13 11.6 0.3 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EER23788.1 - 0.13 11.9 1.3 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EER23788.1 - 0.36 10.7 3.6 0.39 10.6 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EER23788.1 - 1.4 7.8 6.9 0.12 11.3 0.6 2.3 2 1 0 2 2 2 0 Haspin like kinase domain VHS PF00790.19 EER23789.1 - 2.3e-34 118.3 0.5 4e-34 117.5 0.5 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EER23789.1 - 3.7e-17 61.6 0.1 1.1e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EER23789.1 - 2e-14 53.2 0.1 4.1e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EER23789.1 - 1.2e-13 50.5 0.0 2.9e-13 49.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 EER23789.1 - 5e-11 42.8 1.5 1e-10 41.8 0.6 2.1 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EER23789.1 - 0.016 15.1 3.1 0.047 13.6 3.1 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif PIN_9 PF18477.1 EER23789.1 - 0.28 11.5 1.0 9.1 6.6 0.1 2.5 2 0 0 2 2 2 0 PIN like domain CemA PF03040.14 EER23789.1 - 0.85 9.5 3.2 4.7 7.1 0.1 2.2 2 0 0 2 2 2 0 CemA family K_trans PF02705.16 EER23790.1 - 2.7e-133 445.3 20.3 9.8e-69 232.3 8.3 3.0 1 1 1 2 2 2 2 K+ potassium transporter Cyt-b5 PF00173.28 EER23791.1 - 6.7e-23 80.6 0.1 8.5e-23 80.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GTP_EFTU PF00009.27 EER23792.1 - 6.1e-50 169.5 0.0 1.1e-49 168.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EER23792.1 - 2.1e-22 79.2 2.3 3.9e-22 78.3 2.3 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EER23792.1 - 5.9e-09 36.2 0.0 3.3e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EER23792.1 - 1.3e-07 31.7 0.0 3.7e-06 27.0 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EER23792.1 - 4.8e-07 30.1 0.0 1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Gtr1_RagA PF04670.12 EER23792.1 - 0.0016 17.8 0.0 0.0032 16.9 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EER23792.1 - 0.012 15.1 0.1 0.32 10.5 0.1 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Roc PF08477.13 EER23792.1 - 0.017 15.3 0.0 4.6 7.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Prot_ATP_OB_N PF17758.1 EER23792.1 - 0.02 14.5 0.0 0.064 12.9 0.0 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain G-alpha PF00503.20 EER23792.1 - 0.03 13.5 0.1 0.53 9.4 0.1 2.2 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.10 EER23792.1 - 0.079 12.4 1.9 2.2 7.7 0.0 2.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit BLOC1_2 PF10046.9 EER23792.1 - 0.72 10.2 4.0 3.1 8.1 2.8 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HSP70 PF00012.20 EER23793.1 - 9.8e-261 866.2 13.9 1.1e-260 866.0 13.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EER23793.1 - 9.2e-19 67.4 2.1 1.3e-17 63.6 0.3 2.1 1 1 1 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EER23793.1 - 0.0022 17.0 2.2 0.023 13.7 2.2 2.2 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 EER23793.1 - 0.033 13.4 3.8 0.71 9.1 0.2 3.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.6 EER23793.1 - 0.063 13.7 4.4 6.2 7.3 0.5 3.4 3 1 0 3 3 3 0 Cell division protein FtsA Radial_spoke_3 PF06098.11 EER23793.1 - 0.3 10.3 5.8 0.054 12.8 2.1 1.5 2 0 0 2 2 2 0 Radial spoke protein 3 ATP-cone PF03477.16 EER23793.1 - 0.97 10.0 4.8 1 9.9 0.0 3.2 3 1 0 3 3 3 0 ATP cone domain Ntox15 PF15604.6 EER23793.1 - 8.3 6.5 9.0 0.69 10.0 3.6 1.9 2 0 0 2 2 2 0 Novel toxin 15 UCH PF00443.29 EER23795.1 - 1.3e-51 175.6 0.0 1.8e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER23795.1 - 4.7e-18 65.9 0.9 1.3e-16 61.2 0.9 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EER23795.1 - 4.5e-07 30.3 0.0 8.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.19 EER23796.1 - 7.3e-28 97.2 0.2 1.4e-20 73.6 0.0 2.4 1 1 1 2 2 2 2 VHS domain UIM PF02809.20 EER23796.1 - 3.6e-06 26.5 10.7 0.004 17.0 1.7 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif GAT PF03127.14 EER23796.1 - 7.7e-05 22.9 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 GAT domain Ribosomal_S30AE PF02482.19 EER23796.1 - 0.048 14.4 0.1 0.43 11.4 0.4 2.3 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF5496 PF17600.2 EER23796.1 - 0.071 13.2 0.0 1.8 8.6 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5496) MitMem_reg PF13012.6 EER23796.1 - 0.1 13.1 0.2 1 9.8 0.1 2.3 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function TCO89 PF10452.9 EER23797.1 - 4.4e-06 26.0 0.1 0.00063 18.8 0.0 3.4 3 1 0 3 3 3 2 TORC1 subunit TCO89 RCC1 PF00415.18 EER23798.1 - 8.6e-21 74.3 0.5 5.9e-07 30.0 0.0 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EER23798.1 - 9.1e-16 58.1 0.0 8.8e-08 32.4 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 EER23798.1 - 2.9e-09 37.3 0.2 3.2e-08 33.9 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.6 EER23798.1 - 5.6e-09 35.6 2.2 1.6e-06 27.7 0.1 3.5 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_2 PF12796.7 EER23798.1 - 3.2e-06 27.6 0.2 7.9e-06 26.4 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EER23798.1 - 3.4e-06 27.0 0.8 0.17 12.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EER23798.1 - 7.4e-06 26.1 0.4 0.4 11.1 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EER23798.1 - 0.00092 19.6 1.4 0.71 10.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat PRP3 PF08572.10 EER23798.1 - 1.4 8.6 8.9 1.1 8.9 0.7 3.1 3 0 0 3 3 3 0 pre-mRNA processing factor 3 (PRP3) ATG13 PF10033.9 EER23799.1 - 2.7e-67 227.0 0.0 4.4e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 Cupin_2 PF07883.11 EER23800.1 - 0.00018 21.1 1.3 0.00054 19.6 1.3 1.7 1 1 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EER23800.1 - 0.00021 20.9 0.1 0.00038 20.1 0.1 1.4 1 0 0 1 1 1 1 Cupin ARD PF03079.14 EER23800.1 - 0.011 15.9 0.1 0.016 15.4 0.1 1.2 1 0 0 1 1 1 0 ARD/ARD' family AraC_binding PF02311.19 EER23800.1 - 0.031 14.2 0.4 0.051 13.5 0.4 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 EER23800.1 - 0.062 13.0 0.1 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF861) NUC153 PF08159.12 EER23801.1 - 7.8e-14 51.2 1.1 2e-13 49.9 1.1 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EER23801.1 - 1.2e-06 29.1 0.1 0.91 10.5 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23801.1 - 0.005 17.1 0.0 0.27 11.6 0.0 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Med13_C PF06333.12 EER23802.1 - 2e-84 283.7 5.6 2e-84 283.7 5.6 1.7 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EER23802.1 - 2.6e-31 109.2 0.0 5.3e-31 108.2 0.0 1.6 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EER23802.1 - 1.9e-25 90.1 4.0 4.8e-15 56.0 0.6 3.2 2 1 1 3 3 3 2 MID domain of medPIWI T6PP_N PF18572.1 EER23802.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Herpes_US9 PF06072.11 EER23802.1 - 0.18 11.7 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ribosomal_L33 PF00471.20 EER23804.1 - 7.7e-05 23.1 0.0 8.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Calici_coat PF00915.20 EER23805.1 - 0.051 12.5 3.2 0.031 13.2 0.5 1.9 2 0 0 2 2 2 0 Calicivirus coat protein Trimer_CC PF08954.11 EER23805.1 - 0.17 11.5 4.9 1.5 8.4 0.9 3.7 2 0 0 2 2 2 0 Trimerisation motif DUF5403 PF17395.2 EER23805.1 - 1.9 8.9 4.0 1.9 8.8 0.3 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5403) MFS_1 PF07690.16 EER23807.1 - 3.6e-37 128.1 53.6 3.6e-37 128.1 53.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER23807.1 - 2.6e-14 52.6 22.3 5.5e-14 51.5 22.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EER23807.1 - 0.0027 16.1 0.6 0.0027 16.1 0.6 2.8 4 0 0 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family Ceramidase PF05875.12 EER23808.1 - 1.3e-78 264.1 8.0 1.4e-78 264.0 8.0 1.0 1 0 0 1 1 1 1 Ceramidase TauE PF01925.19 EER23808.1 - 2.8 7.5 15.9 0.42 10.2 11.4 1.7 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE FA_hydroxylase PF04116.13 EER23809.1 - 1.4e-22 80.5 11.4 1.4e-22 80.5 11.4 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.25 EER23810.1 - 9.2e-31 106.8 0.0 1.3e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER23810.1 - 4.2e-14 52.7 0.0 5.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER23810.1 - 2.1e-10 40.8 0.3 1.1e-09 38.5 0.3 2.0 1 1 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EER23810.1 - 0.0001 22.8 0.4 0.00031 21.3 0.3 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.6 EER23810.1 - 0.0009 19.2 0.2 0.0015 18.5 0.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EER23810.1 - 0.0012 18.4 0.1 0.0023 17.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 EER23810.1 - 0.0036 16.9 0.1 0.0081 15.8 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EER23810.1 - 0.038 13.9 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.10 EER23810.1 - 0.043 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EER23810.1 - 0.053 12.6 0.0 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 EER23810.1 - 0.074 13.5 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding GDP_Man_Dehyd PF16363.5 EER23810.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Lar_N PF09861.9 EER23810.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Lactate racemase N-terminal domain TrkA_N PF02254.18 EER23810.1 - 0.15 12.3 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Aminotran_1_2 PF00155.21 EER23811.1 - 4.5e-23 82.0 0.0 6e-19 68.4 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class I and II FKBP_C PF00254.28 EER23812.1 - 7.3e-30 103.1 0.0 8.7e-30 102.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cellulase PF00150.18 EER23813.1 - 2.2e-09 37.2 0.2 7.5e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Radical_SAM PF04055.21 EER23813.1 - 0.14 12.5 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Radical SAM superfamily EphA2_TM PF14575.6 EER23813.1 - 0.24 12.3 0.0 0.24 12.3 0.0 3.1 4 1 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 EER23814.1 - 2.5e-60 204.1 0.0 3.3e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23814.1 - 2.5e-32 112.2 0.0 3.4e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER23814.1 - 4.2e-05 23.0 0.0 7.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EER23814.1 - 0.0036 17.2 1.5 0.0049 16.8 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EER23814.1 - 0.011 15.1 0.2 0.022 14.1 0.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EER23814.1 - 0.018 14.0 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EER23814.1 - 0.068 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Endonuc_Holl PF10107.9 EER23814.1 - 0.14 12.0 0.2 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase CCDC84 PF14968.6 EER23814.1 - 0.36 10.4 0.6 0.48 10.0 0.6 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 SNF2_N PF00176.23 EER23815.1 - 3e-62 210.4 0.0 2.1e-58 197.8 0.0 3.3 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EER23815.1 - 2.5e-15 56.8 0.0 7.2e-15 55.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER23815.1 - 7.5e-05 22.8 0.9 0.00026 21.0 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EER23815.1 - 0.00052 19.8 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase BUD22 PF09073.10 EER23815.1 - 0.8 9.0 21.8 0.77 9.0 14.1 2.4 2 0 0 2 2 2 0 BUD22 SIR2 PF02146.17 EER23816.1 - 1.4e-38 132.5 0.0 8e-38 130.1 0.0 1.9 1 1 0 1 1 1 1 Sir2 family Pyridox_ox_2 PF12900.7 EER23817.1 - 1.9e-38 131.6 0.0 2.5e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FR47 PF08445.10 EER23818.1 - 3.5e-06 26.9 0.1 0.0006 19.7 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.25 EER23818.1 - 0.0017 18.6 0.0 0.004 17.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 EER23818.1 - 0.019 15.0 0.0 0.041 14.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EER23818.1 - 0.1 13.3 0.1 0.18 12.5 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain p450 PF00067.22 EER23819.1 - 4.8e-53 180.5 0.0 6.3e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EER23820.1 - 5.7e-14 52.3 0.0 7.5e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23820.1 - 8.9e-12 45.6 0.0 2.3e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER23820.1 - 1.3e-07 31.5 0.0 1.2e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER23820.1 - 7.3e-07 29.7 0.0 1.5e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER23820.1 - 2e-06 28.5 0.0 5.4e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER23820.1 - 0.00047 19.6 0.0 0.19 11.0 0.0 3.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EER23820.1 - 0.0021 17.6 0.0 0.0051 16.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EER23820.1 - 0.0027 17.5 0.0 0.0047 16.7 0.0 1.4 1 1 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 EER23820.1 - 0.036 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 EER23820.1 - 0.038 13.8 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Peptidase_M24 PF00557.24 EER23821.1 - 9.2e-51 172.5 0.0 1.4e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EER23821.1 - 1.3e-28 99.1 0.1 5.1e-28 97.3 0.1 1.9 1 1 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.20 EER23821.1 - 0.051 12.8 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Dfp1_Him1_M PF08630.10 EER23822.1 - 6.8e-40 136.2 1.6 1.5e-39 135.1 0.0 2.4 3 0 0 3 3 3 1 Dfp1/Him1, central region zf-DBF PF07535.12 EER23822.1 - 6.9e-20 70.9 0.0 1.2e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger DUF4472 PF14739.6 EER23822.1 - 0.75 10.5 4.1 21 5.9 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) F-box-like PF12937.7 EER23823.1 - 0.002 18.0 0.1 0.0039 17.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER23823.1 - 0.0078 16.1 0.2 0.039 13.8 0.0 2.3 2 0 0 2 2 2 1 F-box domain Pantoate_transf PF02548.15 EER23824.1 - 1.9e-107 358.5 1.3 2.2e-107 358.3 1.3 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EER23824.1 - 4.6e-09 36.1 0.5 8.2e-09 35.3 0.5 1.6 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase APG12 PF04110.13 EER23825.1 - 1.1e-29 102.6 0.0 1.7e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EER23825.1 - 0.068 13.4 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like NmrA PF05368.13 EER23826.1 - 4.7e-29 101.6 0.4 5.7e-29 101.3 0.4 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EER23826.1 - 4.6e-15 56.0 0.2 1e-14 54.9 0.0 1.6 1 1 1 2 2 2 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EER23826.1 - 5.3e-05 23.6 0.5 0.00027 21.4 0.1 2.2 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EER23826.1 - 0.0054 16.2 0.1 0.015 14.8 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EER23826.1 - 0.0075 16.4 0.4 0.021 15.0 0.1 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 EER23826.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 EER23826.1 - 0.061 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 KR domain DUF1471 PF07338.13 EER23826.1 - 0.096 12.7 0.3 0.36 10.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) UQ_con PF00179.26 EER23827.1 - 2.9e-37 127.4 0.1 3.5e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.6 EER23828.1 - 4.5e-16 59.2 0.0 9.1e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.10 EER23829.1 - 3.4e-31 107.4 4.4 7.5e-31 106.2 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) D123 PF07065.14 EER23831.1 - 7.9e-06 25.2 0.0 3.4e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 D123 R2K_2 PF18299.1 EER23831.1 - 0.003 17.4 0.0 0.0075 16.1 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp domain, R2K clade family 2 ETC_C1_NDUFA5 PF04716.14 EER23831.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 ETC complex I subunit conserved region Sulfotransfer_3 PF13469.6 EER23832.1 - 7.5e-05 23.2 0.1 0.00041 20.8 0.1 2.0 1 1 0 1 1 1 1 Sulfotransferase family Cerato-platanin PF07249.12 EER23833.1 - 6.4e-49 165.0 0.2 7.6e-49 164.8 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.17 EER23833.1 - 0.0077 16.1 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Barwin family p450 PF00067.22 EER23834.1 - 2e-16 59.8 0.1 5.8e-14 51.7 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 Insulin_TMD PF17870.1 EER23834.1 - 5.1 7.3 6.5 1.3 9.1 0.7 2.6 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment MFS_1 PF07690.16 EER23835.1 - 5e-44 150.7 52.1 5e-44 150.7 52.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER23835.1 - 7.3e-16 58.1 39.1 1.6e-15 56.9 11.8 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EER23835.1 - 0.0042 16.0 5.6 0.0042 16.0 5.6 2.4 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 EER23835.1 - 5.5 5.2 11.7 1 7.5 3.7 2.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Flavoprotein PF02441.19 EER23836.1 - 1.8e-13 50.5 0.0 2.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein 3HCDH_N PF02737.18 EER23837.1 - 2.5e-28 99.2 0.0 3.7e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EER23837.1 - 6.1e-24 84.5 0.0 1.1e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EER23837.1 - 2.7e-05 24.2 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EER23837.1 - 0.0031 17.2 0.0 0.0069 16.0 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EER23837.1 - 0.018 15.6 0.0 0.048 14.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EER23837.1 - 0.047 14.0 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAPRTase_N PF17767.1 EER23837.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Osmo_MPGsynth PF09488.10 EER23837.1 - 0.21 10.3 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) Asparaginase_2 PF01112.18 EER23838.1 - 1.4e-50 172.1 0.8 2.8e-39 134.9 0.0 4.6 3 2 0 3 3 3 3 Asparaginase TraQ PF09679.10 EER23839.1 - 0.0024 17.8 0.4 0.0072 16.2 0.0 2.0 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin chaperone (TraQ) Period_C PF12114.8 EER23839.1 - 3.3 7.2 8.9 0.33 10.5 4.2 1.7 2 0 0 2 2 2 0 Period protein 2/3C-terminal region Peptidase_M20 PF01546.28 EER23840.1 - 2.2e-24 86.3 0.0 5.2e-23 81.8 0.0 2.6 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EER23840.1 - 1.3e-09 38.5 13.4 0.14 13.0 0.0 7.0 6 0 0 6 6 6 3 WD domain, G-beta repeat M20_dimer PF07687.14 EER23840.1 - 5.3e-06 26.3 0.0 1.2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain PQQ_3 PF13570.6 EER23840.1 - 8.7 7.0 8.3 1.7e+02 2.9 0.1 5.1 3 1 1 4 4 4 0 PQQ-like domain DUF747 PF05346.11 EER23841.1 - 9.8e-120 399.8 5.2 1.3e-119 399.5 5.2 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family KCH PF16944.5 EER23842.1 - 6.1e-101 337.4 5.6 7.3e-101 337.2 5.6 1.0 1 0 0 1 1 1 1 Fungal potassium channel DUF202 PF02656.15 EER23842.1 - 0.75 10.3 5.7 8.3 6.9 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DctQ PF04290.12 EER23842.1 - 1.7 8.6 8.2 3.1 7.7 1.5 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF21 PF01595.20 EER23843.1 - 6.2e-31 107.5 0.1 9.8e-31 106.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EER23843.1 - 0.00023 21.5 0.0 0.11 12.9 0.0 3.2 2 1 0 2 2 2 2 CBS domain DUF3381 PF11861.8 EER23843.1 - 0.39 10.5 4.0 0.67 9.7 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PspA_IM30 PF04012.12 EER23844.1 - 0.0022 17.6 17.8 0.0022 17.6 17.8 5.1 3 3 2 5 5 5 2 PspA/IM30 family Cep57_CLD_2 PF14197.6 EER23844.1 - 0.0074 16.4 1.8 0.0074 16.4 1.8 8.0 5 3 4 9 9 9 1 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 EER23844.1 - 0.021 14.9 31.5 0.43 10.6 0.1 6.5 3 2 2 6 6 6 0 Protein of unknown function (DUF1664) GAS PF13851.6 EER23844.1 - 0.51 9.7 60.6 0.056 12.8 6.6 5.8 2 1 4 6 6 6 0 Growth-arrest specific micro-tubule binding Filament PF00038.21 EER23844.1 - 1.1 8.7 59.3 3.7 7.0 29.2 4.4 2 1 1 3 3 3 0 Intermediate filament protein CODH_A_N PF18537.1 EER23844.1 - 1.2 9.1 3.9 1.7 8.7 0.1 3.3 3 0 0 3 3 3 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain HALZ PF02183.18 EER23844.1 - 5.8 7.2 11.8 34 4.8 0.4 5.1 3 2 0 3 3 3 0 Homeobox associated leucine zipper MALT1_Ig PF18703.1 EER23844.1 - 6.8 6.7 6.7 1.6 8.7 0.8 2.8 2 1 1 3 3 3 0 MALT1 Ig-like domain DUF3287 PF11690.8 EER23844.1 - 8.6 6.1 7.6 0.77 9.5 1.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) Transket_pyr PF02779.24 EER23845.1 - 3.6e-40 137.5 0.0 5.3e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EER23845.1 - 8.4e-31 106.4 0.0 1.8e-30 105.4 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain His_Phos_1 PF00300.22 EER23846.1 - 2e-13 50.4 0.0 3.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HECT PF00632.25 EER23847.1 - 1.7e-69 234.7 0.0 8.3e-69 232.4 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EER23847.1 - 5.9e-23 80.9 1.3 1.2e-22 79.8 1.3 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf-C2H2_2 PF12756.7 EER23848.1 - 2.8e-40 136.7 10.1 1.8e-32 111.7 4.8 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EER23848.1 - 2.4e-07 30.9 4.5 4.3e-05 23.7 1.6 4.3 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER23848.1 - 2.3e-06 27.8 2.2 2.3e-06 27.8 2.2 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type DUF2024 PF09630.10 EER23848.1 - 0.00015 21.5 2.1 0.079 12.8 0.2 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2024) SnoaL_2 PF12680.7 EER23848.1 - 0.0078 16.8 0.1 0.02 15.5 0.1 1.7 1 0 0 1 1 1 1 SnoaL-like domain zf-C2H2 PF00096.26 EER23848.1 - 0.029 14.8 0.5 0.029 14.8 0.5 5.3 6 0 0 6 6 6 0 Zinc finger, C2H2 type Urm1 PF09138.11 EER23848.1 - 0.032 14.6 0.0 0.073 13.4 0.0 1.5 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) Cytochrome-c551 PF10643.9 EER23848.1 - 0.058 13.0 0.2 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Photosystem P840 reaction-centre cytochrome c-551 Rotamase_2 PF13145.6 EER23848.1 - 0.26 12.1 2.3 0.48 11.3 1.3 1.9 2 0 0 2 2 2 0 PPIC-type PPIASE domain Mso1_Sec1_bdg PF14475.6 EER23848.1 - 3.7 7.2 6.1 0.25 11.0 0.2 2.1 2 0 0 2 2 2 0 Sec1-binding region of Mso1 Rrn6 PF10214.9 EER23849.1 - 0.075 11.5 8.8 0.097 11.2 8.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4407 PF14362.6 EER23849.1 - 0.6 9.4 2.3 0.93 8.8 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1357 PF07094.11 EER23849.1 - 2.7 8.0 9.9 4.1 7.4 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Abhydrolase_3 PF07859.13 EER23850.1 - 4.6e-06 26.6 0.0 9.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EER23850.1 - 0.0045 16.5 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EER23850.1 - 0.0086 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EER23850.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Esterase PF00756.20 EER23850.1 - 0.045 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.18 EER23850.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) LZ_Tnp_IS66 PF13007.7 EER23850.1 - 2.8 8.8 10.5 5.5 7.8 0.1 3.3 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain Pkinase PF00069.25 EER23851.1 - 1.9e-70 237.3 0.0 2.5e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23851.1 - 2.9e-31 108.7 0.0 3.7e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER23851.1 - 5.2e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EER23851.1 - 0.00057 18.9 0.1 0.021 13.8 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EER23851.1 - 0.0035 17.3 0.1 0.0051 16.8 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EER23851.1 - 0.019 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EER23851.1 - 0.2 11.0 0.1 0.61 9.4 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2OG-FeII_Oxy_2 PF13532.6 EER23852.1 - 2e-30 106.5 0.0 2.5e-29 102.9 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Put_Phosphatase PF06888.12 EER23852.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative Phosphatase Amidase PF01425.21 EER23853.1 - 7e-99 331.8 0.0 1.3e-98 331.0 0.0 1.4 1 1 0 1 1 1 1 Amidase PRKG1_interact PF15898.5 EER23854.1 - 0.045 14.6 5.5 0.053 14.4 0.2 2.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Seryl_tRNA_N PF02403.22 EER23854.1 - 0.087 13.1 1.0 0.37 11.1 0.5 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TolA_bind_tri PF16331.5 EER23854.1 - 0.15 12.1 6.1 0.039 14.0 1.9 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF5339 PF17274.2 EER23854.1 - 0.26 12.1 1.6 0.73 10.7 1.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5339) DivIC PF04977.15 EER23854.1 - 1.1 9.1 7.4 0.46 10.3 2.1 2.7 3 0 0 3 3 3 0 Septum formation initiator Anillin_N PF16018.5 EER23854.1 - 4.1 8.1 12.4 1.5 9.4 1.1 4.1 4 0 0 4 4 4 0 Anillin N-terminus adh_short PF00106.25 EER23855.1 - 3.7e-16 59.2 0.0 4.1e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER23855.1 - 6.4e-15 55.4 0.0 7.8e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER23855.1 - 0.00019 21.4 0.0 0.00023 21.1 0.0 1.1 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 EER23856.1 - 2.7e-11 43.0 0.1 3.9e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER23856.1 - 2.8e-06 27.4 10.1 6.8e-06 26.1 10.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase-like PF12876.7 EER23856.1 - 0.1 11.9 0.0 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-binding cellulase-like TPT PF03151.16 EER23857.1 - 1.8e-17 63.6 17.7 2.5e-17 63.2 17.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EER23857.1 - 0.0038 17.4 16.5 0.0038 17.4 16.5 2.6 2 1 0 2 2 2 1 EamA-like transporter family IMUP PF15761.5 EER23857.1 - 0.035 14.8 6.5 0.035 14.8 6.5 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein Herpes_pp85 PF04637.12 EER23857.1 - 6.7 5.0 6.3 11 4.3 6.3 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) AD PF09793.9 EER23858.1 - 1.3e-27 95.7 0.0 1.9e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain 6PGD PF00393.19 EER23859.1 - 1.5e-129 431.5 0.0 1.9e-129 431.2 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EER23859.1 - 2.4e-50 170.8 0.0 3.5e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EER23859.1 - 0.025 14.8 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.22 EER23860.1 - 6.6e-18 64.3 0.0 1e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hexokinase_1 PF00349.21 EER23861.1 - 1.3e-56 191.7 0.0 1.7e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EER23861.1 - 1.1e-47 162.5 0.0 1.6e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase AP_endonuc_2 PF01261.24 EER23862.1 - 5e-29 101.2 0.0 2.1e-28 99.2 0.0 1.9 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel HNH_2 PF13391.6 EER23863.1 - 3.6e-23 81.5 0.0 8.4e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Mad3_BUB1_I PF08311.12 EER23864.1 - 2.9e-43 146.8 0.0 5e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EER23864.1 - 9.6e-13 48.1 0.1 1.2e-11 44.5 0.0 2.7 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EER23864.1 - 1.1e-11 44.6 0.0 1.1e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER23864.1 - 0.0038 16.6 0.0 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EER23864.1 - 0.0052 16.2 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I_2 PF17014.5 EER23864.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Peptidase_C15 PF01470.17 EER23867.1 - 2.1e-13 50.9 0.0 2e-06 28.1 0.0 2.9 2 1 0 2 2 2 2 Pyroglutamyl peptidase AA_permease PF00324.21 EER23868.1 - 3.1e-112 375.6 40.8 3.9e-112 375.3 40.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER23868.1 - 8.9e-33 113.7 43.3 1.1e-32 113.5 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease DNA_pol_phi PF04931.13 EER23869.1 - 4.7e-257 855.0 7.1 5.7e-257 854.7 7.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi Las1 PF04031.13 EER23869.1 - 0.033 14.3 0.6 3.6 7.7 0.0 3.3 3 0 0 3 3 3 0 Las1-like Nop14 PF04147.12 EER23869.1 - 0.034 12.4 16.5 0.064 11.5 16.5 1.5 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EER23869.1 - 0.16 11.4 24.1 0.29 10.5 24.1 1.3 1 0 0 1 1 1 0 SDA1 YolD PF08863.10 EER23869.1 - 0.21 11.6 4.5 1.7 8.7 0.4 3.0 1 1 1 2 2 2 0 YolD-like protein BUD22 PF09073.10 EER23869.1 - 1.5 8.1 24.2 2.9 7.1 24.2 1.4 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EER23869.1 - 7.7 4.7 18.6 13 4.0 18.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DDE_1 PF03184.19 EER23870.1 - 1.9e-20 73.2 0.0 4.6e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 EER23870.1 - 0.00049 19.9 0.0 0.0023 17.7 0.0 2.1 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EER23870.1 - 0.073 13.1 0.2 0.25 11.4 0.2 2.0 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain Rhodanese PF00581.20 EER23871.1 - 4.1e-12 46.6 0.1 8.1e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Rhodanese-like domain SLD5_C PF16922.5 EER23872.1 - 7.2e-10 38.9 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EER23872.1 - 1.5e-07 31.8 0.2 2.8e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein UBM PF14377.6 EER23872.1 - 0.027 13.9 0.1 0.1 12.1 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin binding region UxaE PF16257.5 EER23872.1 - 0.26 9.9 0.0 0.36 9.4 0.0 1.1 1 0 0 1 1 1 0 tagaturonate epimerase Cullin PF00888.22 EER23873.1 - 1.6e-201 671.1 7.8 2.4e-201 670.6 7.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EER23873.1 - 4.6e-27 93.8 0.4 1.8e-26 91.9 0.4 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1388 PF07142.12 EER23873.1 - 0.1 12.6 0.3 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) zf-DNL PF05180.12 EER23874.1 - 2.8e-28 97.7 1.1 4.1e-28 97.1 1.1 1.3 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.18 EER23874.1 - 0.038 13.8 2.4 1.6 8.7 0.2 2.5 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) DRIM PF07539.12 EER23875.1 - 3.6e-199 663.1 0.1 3.6e-199 663.1 0.1 3.9 5 0 0 5 5 5 1 Down-regulated in metastasis TPR_20 PF14561.6 EER23875.1 - 0.049 14.0 0.1 12 6.3 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Katanin_con80 PF13925.6 EER23875.1 - 0.08 13.0 0.1 11 6.0 0.0 3.2 2 0 0 2 2 2 0 con80 domain of Katanin HEAT PF02985.22 EER23875.1 - 0.15 12.4 4.5 0.8 10.1 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat CwfJ_C_1 PF04677.15 EER23876.1 - 1e-24 86.7 0.0 1.6e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EER23876.1 - 1.4e-13 51.5 0.1 3e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 MFS_1 PF07690.16 EER23877.1 - 3.4e-17 62.4 56.7 2.9e-11 42.9 19.0 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily Corona_S2 PF01601.16 EER23878.1 - 1.2 7.5 16.6 1.7 7.1 16.6 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.8 EER23879.1 - 9.1e-20 71.5 9.5 1.1e-19 71.2 9.5 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red SARAF PF06682.12 EER23879.1 - 0.00034 20.4 0.2 0.0004 20.1 0.2 1.1 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis Arf PF00025.21 EER23880.1 - 1.3e-42 145.2 0.0 1.6e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EER23880.1 - 4.3e-19 68.7 0.0 4.8e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER23880.1 - 3.1e-15 56.5 0.0 4.5e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EER23880.1 - 1.5e-07 31.5 0.0 2.3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EER23880.1 - 6.5e-07 28.9 0.0 8.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EER23880.1 - 1.4e-05 24.6 0.0 1.6e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EER23880.1 - 0.00026 20.2 0.0 0.0018 17.5 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 EER23880.1 - 0.0091 16.1 0.1 0.042 13.9 0.2 1.9 1 1 1 2 2 2 1 Dynamin family MMR_HSR1_Xtn PF16897.5 EER23880.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EER23880.1 - 0.034 14.1 0.0 8.2 6.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EER23880.1 - 0.04 13.4 0.2 0.12 11.8 0.0 1.8 2 1 0 2 2 2 0 Ferrous iron transport protein B DUF1979 PF09322.10 EER23880.1 - 0.12 12.3 1.2 4 7.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1979) RNA_pol_Rpb2_6 PF00562.28 EER23881.1 - 3e-115 385.4 0.0 3.9e-115 385.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EER23881.1 - 7.2e-36 123.6 0.0 1.1e-35 123.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EER23881.1 - 1.4e-27 95.6 0.0 3.7e-27 94.3 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EER23881.1 - 1.9e-26 91.8 0.0 4.9e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 EER23881.1 - 6.2e-26 91.2 0.0 1.2e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EER23881.1 - 5.7e-16 58.7 0.0 7.2e-15 55.2 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 Proteasome PF00227.26 EER23882.1 - 1.2e-46 158.7 0.1 1.4e-46 158.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pil1 PF13805.6 EER23883.1 - 1.4e-94 316.5 5.6 1.8e-94 316.2 5.6 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF4559 PF15112.6 EER23883.1 - 0.019 14.7 0.5 0.025 14.3 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) BAR_3 PF16746.5 EER23883.1 - 0.087 12.5 1.9 0.13 11.9 1.9 1.2 1 0 0 1 1 1 0 BAR domain of APPL family DUF3067 PF11267.8 EER23883.1 - 0.09 13.4 0.2 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3067) SWI-SNF_Ssr4 PF08549.10 EER23884.1 - 1.4e-250 833.9 2.8 2e-250 833.4 2.8 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Ppx-GppA PF02541.16 EER23885.1 - 7.4e-44 150.3 0.0 9.6e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 EER23885.1 - 0.032 12.9 0.0 0.055 12.1 0.0 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family MreB_Mbl PF06723.13 EER23885.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Ofd1_CTDD PF10637.9 EER23886.1 - 0.037 13.4 0.2 0.075 12.4 0.1 1.3 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Cwf_Cwc_15 PF04889.12 EER23886.1 - 3.4 7.3 7.4 8.9 6.0 6.2 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EER23886.1 - 7.2 5.8 6.5 11 5.3 6.5 1.3 1 0 0 1 1 1 0 NOA36 protein Thi4 PF01946.17 EER23887.1 - 2e-109 364.3 0.0 2.4e-109 364.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EER23887.1 - 1.1e-07 31.7 1.6 4.4e-07 29.8 1.6 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER23887.1 - 3.7e-06 27.1 0.2 2.2e-05 24.6 0.2 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EER23887.1 - 0.00021 20.5 0.6 0.00038 19.6 0.6 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 EER23887.1 - 0.001 19.1 0.2 0.003 17.6 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EER23887.1 - 0.0014 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EER23887.1 - 0.0077 15.4 0.9 0.032 13.3 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EER23887.1 - 0.04 13.2 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EER23887.1 - 0.051 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EER23887.1 - 0.083 12.2 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EER23887.1 - 0.11 11.3 0.3 0.16 10.8 0.3 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 EER23887.1 - 0.16 10.6 0.6 0.23 10.1 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein Exo_endo_phos PF03372.23 EER23888.1 - 4.3e-14 52.6 0.0 6.7e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EER23889.1 - 2.2e-54 180.2 9.1 2.3e-12 47.2 0.7 7.7 7 2 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23889.1 - 1.2e-21 76.8 0.0 0.0041 17.4 0.0 7.1 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER23889.1 - 3.1e-08 32.7 0.1 0.84 8.2 0.0 4.6 3 1 0 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EER23889.1 - 6.5e-07 28.6 0.0 0.29 10.0 0.0 4.8 2 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EER23889.1 - 0.00015 21.2 0.0 0.00064 19.1 0.0 2.0 2 1 1 3 3 3 1 WD40-like domain PD40 PF07676.12 EER23889.1 - 0.00034 20.5 0.4 31 4.7 0.1 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EER23889.1 - 0.014 13.5 0.0 0.023 12.7 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Frtz PF11768.8 EER23889.1 - 0.049 11.9 0.0 0.075 11.3 0.0 1.2 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz PRIMA1 PF16101.5 EER23889.1 - 0.054 13.5 4.8 0.11 12.5 4.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DUF1513 PF07433.11 EER23889.1 - 0.055 12.5 0.0 0.58 9.2 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) VID27 PF08553.10 EER23889.1 - 0.068 12.2 0.0 3 6.8 0.0 2.4 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain CAP_N PF01213.19 EER23889.1 - 0.15 11.5 3.4 0.26 10.7 3.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal NOA36 PF06524.12 EER23889.1 - 0.17 11.2 8.7 0.36 10.1 8.7 1.5 1 0 0 1 1 1 0 NOA36 protein TLP-20 PF06088.11 EER23889.1 - 0.73 9.7 4.7 2.1 8.2 4.7 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.13 EER23889.1 - 8.3 6.2 11.0 0.9 9.4 5.2 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Glyco_hydro_cc PF11790.8 EER23890.1 - 1.5e-56 191.6 0.0 1.8e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.13 EER23891.1 - 1.5e-07 31.2 4.9 1.5e-07 31.2 4.9 2.4 3 0 0 3 3 3 1 RED-like protein N-terminal region zf-UBR PF02207.20 EER23892.1 - 4.4e-17 62.0 15.4 4.4e-17 62.0 15.4 2.2 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EER23892.1 - 1.7e-05 24.5 0.0 4.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS SDA1 PF05285.12 EER23892.1 - 7 6.0 6.5 13 5.1 6.5 1.4 1 0 0 1 1 1 0 SDA1 UCR_UQCRX_QCR9 PF05365.12 EER23893.1 - 1.7e-29 101.5 2.6 1.9e-29 101.4 2.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF4203 PF13886.6 EER23893.1 - 0.045 13.4 0.0 0.045 13.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) Mago-bind PF09282.10 EER23894.1 - 7.2e-13 48.2 5.0 7.2e-13 48.2 5.0 1.9 2 0 0 2 2 2 1 Mago binding Amino_oxidase PF01593.24 EER23895.1 - 2.2e-27 96.5 0.0 2.7e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EER23895.1 - 1.6e-15 57.1 0.1 4.4e-15 55.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER23895.1 - 1.8e-11 44.2 0.1 4.1e-09 36.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EER23895.1 - 5.6e-06 26.8 0.0 0.0004 20.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER23895.1 - 4.4e-05 22.8 0.0 0.00042 19.6 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EER23895.1 - 0.0001 21.7 0.0 0.00024 20.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER23895.1 - 0.0026 17.8 0.0 0.026 14.5 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EER23895.1 - 0.0032 16.8 0.1 1.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain MCRA PF06100.11 EER23895.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 MCRA family NAD_Gly3P_dh_N PF01210.23 EER23895.1 - 0.014 15.4 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.24 EER23895.1 - 0.015 14.4 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 EER23895.1 - 0.017 14.5 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EER23895.1 - 0.025 15.0 0.0 7.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding K_oxygenase PF13434.6 EER23895.1 - 0.03 13.5 0.0 0.077 12.1 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 EER23895.1 - 0.035 14.2 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EER23895.1 - 0.036 12.8 0.0 0.13 10.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.16 EER23895.1 - 0.042 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EER23895.1 - 0.042 13.1 0.0 6 6.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Mqo PF06039.15 EER23895.1 - 0.12 10.9 0.0 1.7 7.1 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.6 EER23895.1 - 0.19 10.9 0.0 0.77 9.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCCH_2 PF14608.6 EER23896.1 - 2e-10 40.8 52.0 0.001 19.4 10.8 5.5 5 1 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EER23896.1 - 0.0082 16.4 0.0 0.014 15.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_hydro_20 PF00728.22 EER23897.1 - 1.5e-78 264.7 0.0 1.9e-78 264.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EER23897.1 - 1.8e-27 96.6 0.0 7.5e-27 94.7 0.0 2.1 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EER23897.1 - 1.2e-05 26.1 0.0 0.0007 20.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.22 EER23898.1 - 2.1e-60 204.8 0.0 2.3e-59 201.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 AP3B1_C PF14796.6 EER23898.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Glyco_hydro_16 PF00722.21 EER23899.1 - 2.7e-43 147.5 1.5 4.2e-43 146.8 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 EER23899.1 - 0.036 14.2 0.4 0.085 13.0 0.4 1.6 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Hep_59 PF07052.11 EER23900.1 - 0.081 13.7 0.1 0.19 12.5 0.1 1.6 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 tRNA-synt_1b PF00579.25 EER23901.1 - 1.6e-62 211.5 0.0 2e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PP2C PF00481.21 EER23902.1 - 1.8e-52 178.5 0.1 2.8e-52 177.9 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EER23902.1 - 4.9e-38 128.7 60.6 4e-08 32.9 4.8 10.5 6 4 3 11 11 11 9 Leucine rich repeat LRR_4 PF12799.7 EER23902.1 - 7.9e-31 105.6 58.9 0.00026 21.3 1.1 12.0 6 3 1 11 11 11 8 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EER23902.1 - 5.3e-27 94.6 0.0 1.9e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 EER23902.1 - 1.9e-11 43.5 0.0 5.9e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 EER23902.1 - 1e-06 28.4 16.5 0.0091 15.5 1.0 4.6 2 1 2 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EER23902.1 - 2.4e-05 24.3 51.3 0.33 11.7 0.6 16.0 17 2 0 17 17 17 2 Leucine Rich Repeat LRR_5 PF13306.6 EER23902.1 - 0.00099 19.1 6.8 0.11 12.5 0.3 3.7 4 0 0 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_2 PF07723.13 EER23902.1 - 2.8 8.7 4.1 67 4.4 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat MSC PF09402.10 EER23903.1 - 2.2e-108 362.7 0.0 3e-108 362.3 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EER23903.1 - 2.6e-16 59.0 0.1 5.9e-16 57.9 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 EER23903.1 - 0.078 12.8 0.3 5.8 6.8 0.0 3.6 3 1 0 3 3 3 0 SAP domain Aminotran_1_2 PF00155.21 EER23904.1 - 1.9e-76 257.6 0.0 2.2e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DJ-1_PfpI PF01965.24 EER23905.1 - 1.4e-16 60.7 0.0 2.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family IMS PF00817.20 EER23907.1 - 1.3e-41 142.1 0.0 7.2e-41 139.7 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family REV1_C PF16727.5 EER23907.1 - 2.2e-26 92.1 2.3 6.2e-26 90.6 2.3 1.8 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 EER23907.1 - 1.5e-15 56.1 6.2 2.1e-07 30.1 1.4 3.3 2 0 0 2 2 2 2 Ubiquitin binding region IMS_C PF11799.8 EER23907.1 - 3.8e-14 53.4 0.0 8.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EER23907.1 - 1.9e-09 37.8 0.0 5.6e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EER23907.1 - 6.4e-07 29.7 0.0 2.4e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EER23907.1 - 5.7e-06 26.5 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EER23907.1 - 0.0014 18.5 0.0 0.0054 16.6 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain mCpol PF18182.1 EER23907.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 minimal CRISPR polymerase domain IMS_HHH PF11798.8 EER23907.1 - 0.011 16.1 0.1 0.058 13.7 0.0 2.3 2 0 0 2 2 2 0 IMS family HHH motif DUF4381 PF14316.6 EER23907.1 - 0.13 12.5 0.1 0.7 10.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) NPL PF17800.1 EER23908.1 - 6.9e-33 113.4 0.0 6.9e-33 113.4 0.0 2.0 2 1 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 EER23908.1 - 2.3e-32 111.1 0.0 7.6e-32 109.5 0.0 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Utp14 PF04615.13 EER23908.1 - 6.3 5.2 32.9 0.37 9.3 4.7 2.1 2 0 0 2 2 2 0 Utp14 protein Pkinase PF00069.25 EER23909.1 - 2.8e-49 167.9 0.1 7.3e-26 91.1 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EER23909.1 - 1.1e-21 77.2 0.0 1.2e-12 47.6 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EER23909.1 - 0.0012 18.8 0.1 0.0025 17.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EER23909.1 - 0.0081 15.2 0.2 0.015 14.3 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain DUF3591 PF12157.8 EER23910.1 - 1e-182 607.7 0.1 1.7e-182 607.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EER23910.1 - 0.005 16.9 0.7 0.0087 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EER23910.1 - 0.0067 16.2 1.2 0.016 15.0 1.2 1.6 1 0 0 1 1 1 1 Zinc knuckle FlxA PF14282.6 EER23910.1 - 0.97 9.5 14.2 8.9 6.4 5.5 2.9 1 1 1 2 2 2 0 FlxA-like protein Methyltransf_15 PF09445.10 EER23911.1 - 9.4e-52 174.9 0.0 1.2e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EER23911.1 - 3.9e-12 46.3 0.0 5e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EER23911.1 - 8.2e-08 32.1 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EER23911.1 - 4.3e-07 29.8 0.0 1.2e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EER23911.1 - 0.00012 22.0 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EER23911.1 - 0.00069 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER23911.1 - 0.00086 20.0 0.0 0.0015 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EER23911.1 - 0.0012 18.4 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 MraW methylase family MTS PF05175.14 EER23911.1 - 0.0015 18.2 0.0 0.0021 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.17 EER23911.1 - 0.0038 16.4 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.13 EER23911.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.17 EER23911.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_11 PF08241.12 EER23911.1 - 0.1 13.2 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GRASP55_65 PF04495.14 EER23912.1 - 3.8e-42 143.9 0.0 1.3e-40 138.9 0.0 2.2 1 1 1 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EER23912.1 - 0.013 15.3 0.0 0.57 10.1 0.0 2.4 2 0 0 2 2 2 0 PDZ domain ApoO PF09769.9 EER23913.1 - 9.8e-42 142.0 0.2 2.7e-41 140.6 0.1 1.7 1 1 0 1 1 1 1 Apolipoprotein O RP1-2 PF12042.8 EER23913.1 - 0.035 14.0 0.7 0.082 12.8 0.7 1.6 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain Peptidase_M3 PF01432.20 EER23914.1 - 7.3e-123 411.2 0.0 9.6e-123 410.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EER23914.1 - 0.032 13.9 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like APH PF01636.23 EER23915.1 - 2e-10 41.0 0.0 1.1e-09 38.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 EER23916.1 - 5.6e-13 49.4 0.8 3.5e-12 46.7 0.8 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER23916.1 - 0.00024 20.7 0.1 0.00044 19.9 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase Proteasome PF00227.26 EER23919.1 - 5.9e-45 153.1 0.1 7.3e-45 152.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EER23919.1 - 4.2e-14 51.7 0.7 4.2e-14 51.7 0.7 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUP214 PF16755.5 EER23920.1 - 3.5e-07 29.8 0.0 2.2e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 FGGY_C PF02782.16 EER23920.1 - 0.041 13.6 0.1 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Syntaxin-6_N PF09177.11 EER23920.1 - 0.064 13.8 2.2 0.086 13.4 0.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ANAPC4_WD40 PF12894.7 EER23920.1 - 0.13 12.6 0.0 8 6.8 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain OmpH PF03938.14 EER23920.1 - 0.43 10.9 4.3 2.6 8.4 0.2 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SlyX PF04102.12 EER23920.1 - 3.4 8.3 11.6 4.6 7.9 0.3 4.2 4 0 0 4 4 4 0 SlyX FMO-like PF00743.19 EER23921.1 - 7.2e-14 51.1 0.0 1.3e-12 46.9 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EER23921.1 - 5.5e-10 39.0 0.0 3.2e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER23921.1 - 4.8e-08 33.1 0.0 1.6e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EER23921.1 - 4.5e-06 26.0 0.1 0.00015 21.0 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EER23921.1 - 1.9e-05 24.4 0.2 0.021 14.4 0.1 4.0 2 2 1 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.17 EER23921.1 - 2.3e-05 23.8 0.0 9.8e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EER23921.1 - 2.4e-05 23.7 0.0 0.00031 20.1 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER23921.1 - 0.00044 20.7 0.0 0.24 12.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EER23921.1 - 0.0019 18.3 0.0 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 EER23921.1 - 0.0053 16.8 0.1 9.1 6.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.15 EER23921.1 - 0.032 12.8 0.0 2.7 6.5 0.0 2.4 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.12 EER23921.1 - 0.058 12.4 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EER23921.1 - 0.076 13.5 0.0 0.27 11.7 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.18 EER23922.1 - 8e-14 51.3 0.4 1.8e-13 50.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER23922.1 - 1.6e-07 31.3 9.6 3.2e-07 30.4 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEPN_Toprim_N PF18871.1 EER23923.1 - 0.072 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 Acetyltransf_1 PF00583.25 EER23924.1 - 2.1e-10 40.8 0.0 1e-08 35.4 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER23924.1 - 3.9e-09 36.8 0.1 1.3e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER23924.1 - 7.4e-08 32.4 0.0 3.6e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EER23924.1 - 0.00032 20.4 0.0 0.00053 19.7 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family FR47 PF08445.10 EER23924.1 - 0.0009 19.2 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EER23924.1 - 0.0017 18.4 0.0 0.0063 16.6 0.0 1.9 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain ABM PF03992.16 EER23926.1 - 0.00046 20.2 0.1 0.15 12.2 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase KH_1 PF00013.29 EER23927.1 - 3.1e-43 145.4 3.4 8.3e-18 64.0 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EER23927.1 - 7.4e-10 38.5 1.9 0.01 15.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EER23927.1 - 1.7e-05 24.8 6.7 0.24 11.5 0.2 3.4 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 EER23927.1 - 0.00011 22.1 0.0 0.05 13.6 0.0 2.4 2 0 0 2 2 2 2 KH-like RNA-binding domain KH_4 PF13083.6 EER23927.1 - 0.0011 18.7 1.1 1.1 9.2 0.1 3.3 3 0 0 3 3 3 1 KH domain CENP-K PF11802.8 EER23928.1 - 8.7e-06 25.5 5.7 0.0035 17.0 6.2 2.4 2 1 0 2 2 2 2 Centromere-associated protein K Cortex-I_coil PF09304.10 EER23928.1 - 0.17 12.1 18.1 1.5 9.0 11.0 3.0 3 1 0 3 3 3 0 Cortexillin I, coiled coil HAUS-augmin3 PF14932.6 EER23928.1 - 1.1 8.8 11.6 0.43 10.1 5.4 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 HAUS6_N PF14661.6 EER23928.1 - 1.5 8.4 10.5 0.29 10.7 5.5 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus MCU PF04678.13 EER23928.1 - 8.3 6.5 8.8 7.9 6.5 5.2 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Abhydrolase_1 PF00561.20 EER23929.1 - 6.4e-14 52.2 0.0 1e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER23929.1 - 6e-07 29.0 0.0 1.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EER23929.1 - 0.015 15.9 0.0 0.026 15.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 EER23929.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Pyridoxal_deC PF00282.19 EER23930.1 - 1.8e-26 92.7 0.0 3.1e-26 92.0 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EER23930.1 - 0.0026 17.0 0.0 0.0042 16.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EER23930.1 - 0.014 14.7 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase RWP-RK PF02042.15 EER23930.1 - 0.094 12.7 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 RWP-RK domain Aminotran_5 PF00266.19 EER23930.1 - 0.14 11.0 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF4110 PF13422.6 EER23931.1 - 3.6e-34 116.7 0.8 3.6e-34 116.7 0.8 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.6 EER23931.1 - 5.7e-29 99.9 10.2 9.1e-10 38.4 0.0 6.7 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EER23931.1 - 2.8e-27 94.4 11.2 1.5e-09 37.9 0.1 7.0 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EER23931.1 - 1.8e-20 72.4 2.4 1.4e-05 25.0 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EER23931.1 - 1.6e-19 69.0 3.6 1.1e-05 25.2 0.0 6.1 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 EER23931.1 - 2.2e-18 65.8 2.8 0.00069 19.8 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EER23931.1 - 1.9e-17 62.5 0.4 1.1e-05 25.0 0.0 5.7 5 1 0 5 5 5 3 Kelch motif S-antigen PF05756.11 EER23931.1 - 0.024 15.0 2.0 0.1 13.0 2.0 2.1 1 0 0 1 1 1 0 S-antigen protein TFA2_Winged_2 PF18121.1 EER23931.1 - 0.025 14.2 0.4 2.1 8.1 0.0 2.6 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 RQC PF09382.10 EER23932.1 - 1.9e-21 75.9 0.0 5e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 EER23932.1 - 1.1e-20 74.0 1.4 3e-17 63.0 0.0 3.7 3 1 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 EER23932.1 - 1.9e-20 73.4 0.7 1e-19 71.0 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EER23932.1 - 4.1e-15 56.3 9.8 1.7e-14 54.3 9.8 2.2 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 EER23932.1 - 1.1e-06 28.5 0.0 2.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 EER23932.1 - 4.1e-06 26.9 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EER23932.1 - 0.015 14.6 0.0 0.058 12.7 0.0 1.9 2 0 0 2 2 2 0 SecA DEAD-like domain DnaG_DnaB_bind PF08278.11 EER23932.1 - 0.054 14.1 0.3 20 5.8 0.0 2.9 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding Mon1 PF03164.14 EER23933.1 - 4e-155 516.9 0.0 4.9e-155 516.6 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 EER23934.1 - 1e-116 389.4 0.2 8.8e-116 386.3 0.0 2.6 3 0 0 3 3 3 1 Dopey, N-terminal zf-HIT PF04438.16 EER23936.1 - 1.5e-09 37.6 5.8 2.2e-09 37.0 5.8 1.3 1 0 0 1 1 1 1 HIT zinc finger MBOAT PF03062.19 EER23937.1 - 2.4e-44 152.1 13.5 3.4e-44 151.6 13.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.11 EER23937.1 - 0.0046 17.0 0.5 0.9 9.7 0.1 2.5 2 0 0 2 2 2 2 PufQ cytochrome subunit T4SS_CagC PF16943.5 EER23937.1 - 0.14 12.3 0.4 0.3 11.3 0.4 1.5 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system adh_short_C2 PF13561.6 EER23938.1 - 8e-49 166.3 0.0 1.1e-48 165.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER23938.1 - 3.9e-46 157.0 0.1 4.7e-46 156.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER23938.1 - 1.2e-08 35.1 0.1 1.6e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EER23938.1 - 0.0039 16.6 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 EER23938.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme THF_DHG_CYH_C PF02882.19 EER23938.1 - 0.045 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2974 PF11187.8 EER23938.1 - 0.053 13.1 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Eno-Rase_NADH_b PF12242.8 EER23938.1 - 0.056 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.6 EER23938.1 - 0.27 11.7 1.1 0.67 10.4 1.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding polyprenyl_synt PF00348.17 EER23939.1 - 1.5e-50 171.7 0.0 2.4e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase zf-CGNR PF11706.8 EER23939.1 - 0.22 11.4 2.3 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 CGNR zinc finger AOX PF01786.17 EER23940.1 - 7.8e-99 329.6 0.2 9.5e-99 329.3 0.2 1.1 1 0 0 1 1 1 1 Alternative oxidase Acylphosphatase PF00708.18 EER23941.1 - 1.3e-26 92.8 0.4 1.5e-26 92.6 0.4 1.0 1 0 0 1 1 1 1 Acylphosphatase BLUF PF04940.12 EER23941.1 - 0.0005 20.1 0.0 0.00057 20.0 0.0 1.2 1 0 0 1 1 1 1 Sensors of blue-light using FAD DUF2871 PF11070.8 EER23941.1 - 0.15 12.3 0.1 0.21 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2871) KAR9 PF08580.10 EER23943.1 - 8.9e-264 877.2 0.6 8.9e-264 877.2 0.6 2.3 2 1 0 2 2 2 1 Yeast cortical protein KAR9 Tropomyosin PF00261.20 EER23943.1 - 0.031 13.7 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 Tropomyosin T3SSipB PF16535.5 EER23943.1 - 0.2 12.1 1.8 0.44 11.0 0.6 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB PLU-1 PF08429.11 EER23943.1 - 0.36 9.9 2.2 1.9 7.6 0.0 2.6 3 0 0 3 3 3 0 PLU-1-like protein Spectrin PF00435.21 EER23943.1 - 0.51 10.8 6.1 5.3 7.6 1.0 3.5 3 1 0 3 3 3 0 Spectrin repeat Laminin_II PF06009.12 EER23943.1 - 1.7 8.6 4.4 4.8 7.2 0.0 3.4 2 2 2 4 4 4 0 Laminin Domain II zf-B_box PF00643.24 EER23944.1 - 4.4 7.5 11.1 10 6.4 0.0 2.6 2 0 0 2 2 2 0 B-box zinc finger Mito_carr PF00153.27 EER23945.1 - 3.8e-57 190.2 1.2 7.8e-18 64.2 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.7 EER23946.1 - 7.4e-09 35.4 0.4 1.4e-08 34.5 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER23946.1 - 2.2e-05 24.2 0.0 5.8e-05 22.9 0.1 1.8 1 1 1 2 2 2 1 F-box domain MIT PF04212.18 EER23946.1 - 0.19 11.8 0.3 0.35 10.9 0.3 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain ANAPC2 PF08672.11 EER23947.1 - 2.6e-22 79.1 0.1 1.1e-21 77.0 0.1 2.2 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 EER23947.1 - 2.2e-20 72.9 1.7 6e-20 71.4 0.4 1.9 2 0 0 2 2 2 1 Cullin family HbrB PF08539.11 EER23947.1 - 0.07 13.1 1.2 2.2 8.2 0.0 2.9 3 0 0 3 3 3 0 HbrB-like FeoC PF09012.10 EER23947.1 - 0.12 12.5 0.1 12 6.1 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_5 PF01022.20 EER23947.1 - 0.14 12.1 1.0 0.52 10.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Pkr1 PF08636.10 EER23948.1 - 1.6e-31 108.3 7.6 2.1e-31 107.8 7.6 1.2 1 0 0 1 1 1 1 ER protein Pkr1 zf-C2H2 PF00096.26 EER23949.1 - 0.00014 22.1 2.4 0.32 11.5 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER23949.1 - 0.0013 19.4 1.4 0.78 10.7 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EER23949.1 - 0.056 13.5 0.4 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_EFTU PF00009.27 EER23950.1 - 1.1e-06 28.3 0.0 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EER23950.1 - 0.0022 17.9 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EER23950.1 - 0.0045 17.5 0.0 0.0096 16.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ATP_bind_1 PF03029.17 EER23950.1 - 0.075 12.8 0.1 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein LSM PF01423.22 EER23951.1 - 7e-18 64.1 0.0 9.1e-18 63.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EER23951.1 - 0.0038 17.3 0.0 0.0053 16.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 EER23951.1 - 3.3 6.4 7.6 4.3 6.0 7.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MTS PF05175.14 EER23952.1 - 0.016 14.7 0.1 0.58 9.7 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase small domain Complex1_LYR_2 PF13233.6 EER23953.1 - 2.7e-20 72.9 0.6 3.5e-20 72.5 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EER23953.1 - 8.8e-11 41.7 0.4 1.6e-10 40.8 0.3 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EER23953.1 - 0.0059 17.2 0.1 0.0074 16.9 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like TauD PF02668.16 EER23954.1 - 4e-28 99.0 0.0 5.3e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1157 PF06636.11 EER23954.1 - 0.17 10.7 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) HA2 PF04408.23 EER23955.1 - 2.1e-21 76.2 0.1 4.4e-21 75.2 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EER23955.1 - 9.9e-12 45.1 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EER23955.1 - 1.1e-11 45.1 0.0 3e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EER23955.1 - 0.00034 20.4 0.0 0.0017 18.1 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EER23955.1 - 0.0023 18.2 0.0 0.0065 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EER23955.1 - 0.0044 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EER23955.1 - 0.044 13.5 0.0 2.5 7.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EER23955.1 - 0.078 12.3 0.0 0.29 10.5 0.0 1.9 2 0 0 2 2 2 0 KaiC RsgA_GTPase PF03193.16 EER23955.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase DUF4378 PF14309.6 EER23956.1 - 0.015 15.7 4.1 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4378) Ribosomal_L16 PF00252.18 EER23957.1 - 1.3e-43 148.2 0.0 1.8e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NAM-associated PF14303.6 EER23958.1 - 5.3e-05 24.0 0.7 0.036 14.8 0.0 3.6 2 2 1 3 3 3 1 No apical meristem-associated C-terminal domain YwqJ-deaminase PF14431.6 EER23958.1 - 0.0029 17.8 3.6 0.011 15.9 3.6 2.1 1 1 0 1 1 1 1 YwqJ-like deaminase DUF2536 PF10750.9 EER23958.1 - 0.0035 17.2 0.0 0.0092 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2536) DUF948 PF06103.11 EER23958.1 - 0.016 15.5 0.9 0.038 14.2 0.9 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) TTKRSYEDQ PF10212.9 EER23958.1 - 0.17 10.9 10.0 0.0099 14.9 1.5 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Not3 PF04065.15 EER23958.1 - 0.21 11.0 15.0 0.75 9.2 13.1 2.6 2 1 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF1515 PF07439.11 EER23958.1 - 3.5 7.7 8.7 2 8.5 4.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TPR_MLP1_2 PF07926.12 EER23958.1 - 3.5 7.7 31.8 0.31 11.1 17.9 3.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.11 EER23958.1 - 9.1 6.8 8.2 7.7 7.0 0.7 3.5 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Clat_adaptor_s PF01217.20 EER23959.1 - 1.4e-12 47.7 0.0 2.4e-11 43.7 0.2 2.0 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Peptidase_S80 PF07230.11 EER23959.1 - 0.046 12.0 0.0 0.074 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) FbpA PF05833.11 EER23960.1 - 3.6e-37 128.2 10.3 3.6e-37 128.2 10.3 1.9 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 EER23960.1 - 1.2e-34 118.4 0.0 1.2e-34 118.4 0.0 3.2 4 0 0 4 4 4 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 EER23960.1 - 2.2e-28 99.1 0.0 5.1e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF2067 PF09840.9 EER23960.1 - 0.0048 16.5 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) Sua5_yciO_yrdC PF01300.18 EER23961.1 - 1.9e-56 190.4 0.0 3.4e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EER23961.1 - 3.3e-32 111.9 0.0 7.4e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding APH PF01636.23 EER23962.1 - 0.0021 18.0 0.0 0.0038 17.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EER23963.1 - 1e-05 25.0 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain ERM PF00769.19 EER23963.1 - 1.4e-05 25.1 13.2 1.8e-05 24.7 13.2 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family APH PF01636.23 EER23963.1 - 0.006 16.5 0.1 0.006 16.5 0.1 3.0 3 1 1 4 4 4 1 Phosphotransferase enzyme family DDHD PF02862.17 EER23963.1 - 0.073 13.2 2.9 0.12 12.5 2.9 1.3 1 0 0 1 1 1 0 DDHD domain TAF4 PF05236.14 EER23963.1 - 0.11 12.2 12.0 0.17 11.6 12.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family FmiP_Thoc5 PF09766.9 EER23963.1 - 0.16 11.2 7.6 0.14 11.4 5.6 1.8 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 eIF3_subunit PF08597.10 EER23963.1 - 2.5 7.9 17.7 4 7.3 17.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit ARGLU PF15346.6 EER23963.1 - 3.2 7.6 41.7 5.5 6.9 41.7 1.3 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 2Fe-2S_thioredx PF01257.19 EER23965.1 - 3.1e-59 199.0 0.1 4.1e-59 198.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SNF2_N PF00176.23 EER23966.1 - 9.4e-19 67.3 0.0 2.4e-12 46.3 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 EER23966.1 - 9.2e-18 64.7 0.0 2e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 EER23966.1 - 3e-05 24.3 0.0 6.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SusD-like_3 PF14322.6 EER23966.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Starch-binding associating with outer membrane ResIII PF04851.15 EER23966.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-piccolo PF05715.13 EER23966.1 - 0.22 11.7 6.0 0.59 10.3 6.0 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger CSTF2_hinge PF14327.6 EER23967.1 - 7.2e-32 109.7 1.8 7.2e-32 109.7 1.8 2.2 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EER23967.1 - 1.9e-19 69.3 0.0 3e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EER23967.1 - 9.4e-17 60.3 10.8 3.1e-16 58.7 10.8 2.0 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 EER23967.1 - 0.0046 16.8 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 Occluded RNA-recognition motif Spo7_2_N PF15407.6 EER23967.1 - 0.017 14.8 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_7 PF16367.5 EER23967.1 - 0.047 13.8 0.1 2.3 8.4 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif RRM_Rrp7 PF17799.1 EER23967.1 - 0.11 12.2 0.0 8.5 6.2 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain MCCD1 PF15707.5 EER23967.1 - 1 9.9 4.9 0.59 10.6 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial coiled-coil domain protein 1 Band_7 PF01145.25 EER23968.1 - 2.1e-22 80.0 6.0 4.4e-22 79.0 6.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.19 EER23968.1 - 0.015 14.8 0.7 0.022 14.3 0.7 1.3 1 0 0 1 1 1 0 MraW methylase family Ferritin_2 PF13668.6 EER23969.1 - 8.7e-38 129.6 0.0 1.1e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.14 EER23969.1 - 0.06 12.9 0.1 0.089 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Ank_2 PF12796.7 EER23970.1 - 0.0009 19.8 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EER23970.1 - 0.057 13.9 0.0 0.27 11.8 0.0 2.3 1 1 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 EER23970.1 - 0.085 13.5 0.0 0.83 10.3 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) MCM PF00493.23 EER23971.1 - 2.1e-101 337.7 0.0 3.2e-101 337.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EER23971.1 - 4.8e-39 133.1 1.3 9.5e-39 132.1 1.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EER23971.1 - 6.2e-29 100.3 2.1 6.2e-29 100.3 2.1 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EER23971.1 - 4.8e-18 65.7 0.1 1.8e-17 63.8 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EER23971.1 - 6.8e-06 25.6 0.0 0.00019 20.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EER23971.1 - 3.5e-05 23.8 0.0 0.00013 21.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EER23971.1 - 0.0012 18.7 0.0 0.0038 17.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EER23971.1 - 0.088 12.5 0.1 4.8 6.8 0.0 3.2 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_32 PF13654.6 EER23971.1 - 1.2 7.8 4.7 0.46 9.2 0.7 2.1 2 0 0 2 2 2 0 AAA domain VTC PF09359.10 EER23972.1 - 1.9e-101 339.1 0.6 2.9e-101 338.5 0.6 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 EER23972.1 - 1.1e-12 48.7 14.8 2.1e-05 24.6 0.9 3.9 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 EER23972.1 - 2.4e-11 43.9 4.3 2.4e-11 43.9 4.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ribophorin_I PF04597.14 EER23973.1 - 1.8e-148 495.4 0.0 2.1e-148 495.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Indigoidine_A PF04227.12 EER23974.1 - 2.6e-116 388.1 1.2 4.7e-109 364.3 0.1 2.2 1 1 1 2 2 2 2 Indigoidine synthase A like protein PfkB PF00294.24 EER23974.1 - 1.4e-12 47.5 0.1 2.1e-06 27.3 0.0 2.7 2 0 0 2 2 2 2 pfkB family carbohydrate kinase ICAT PF06384.11 EER23974.1 - 0.2 11.9 0.5 0.69 10.2 0.5 1.9 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT SnoaL_2 PF12680.7 EER23975.1 - 5.3e-07 30.2 0.1 1.4e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.12 EER23975.1 - 0.0012 18.6 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF3880 PF12996.7 EER23975.1 - 0.03 14.4 0.1 0.066 13.3 0.1 1.5 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) RSN1_7TM PF02714.15 EER23976.1 - 1.3e-82 277.3 32.4 1.3e-82 277.3 32.4 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EER23976.1 - 6.4e-47 159.2 0.3 6.4e-47 159.2 0.3 3.8 4 1 1 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EER23976.1 - 8.6e-30 104.3 3.8 2.7e-17 63.5 0.5 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EER23976.1 - 4.6e-12 46.0 1.7 6.3e-12 45.5 0.0 2.1 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Flavokinase PF01687.17 EER23977.1 - 1.3e-31 109.2 0.0 1e-30 106.3 0.0 1.9 1 1 0 1 1 1 1 Riboflavin kinase PAS PF00989.25 EER23979.1 - 0.066 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold Zn_clus PF00172.18 EER23979.1 - 0.19 11.9 13.0 0.046 13.9 9.7 1.7 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EER23980.1 - 1.1e-38 133.2 42.5 1.1e-38 133.2 42.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER23980.1 - 2.6e-05 22.8 3.5 2.6e-05 22.8 3.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pex24p PF06398.11 EER23980.1 - 0.49 9.3 3.0 2.4 7.1 3.0 2.3 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Rad21_Rec8_N PF04825.13 EER23981.1 - 1.7e-37 128.0 0.0 3.3e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EER23981.1 - 4.2e-08 32.3 0.2 9.4e-08 31.2 0.2 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein SMC_ScpA PF02616.14 EER23981.1 - 0.021 14.8 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Segregation and condensation protein ScpA E1-E2_ATPase PF00122.20 EER23982.1 - 2.8e-46 157.3 0.2 2.8e-46 157.3 0.2 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EER23982.1 - 3.9e-45 153.8 3.5 7.1e-45 153.0 0.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EER23982.1 - 7e-22 76.9 0.0 2.5e-21 75.1 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EER23982.1 - 4.8e-20 72.8 0.9 3.7e-19 69.9 0.9 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EER23982.1 - 5.4e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EER23982.1 - 6.7e-05 22.8 1.4 0.00041 20.2 0.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EER23982.1 - 0.15 12.5 0.0 0.33 11.3 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ammonium_transp PF00909.21 EER23983.1 - 1.1e-115 386.6 30.9 1.3e-115 386.4 30.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG4 PF08318.12 EER23984.1 - 2.3e-123 411.6 0.0 3e-123 411.2 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein YopE_N PF09020.10 EER23984.1 - 0.12 12.7 0.4 33 4.8 0.0 3.2 2 2 0 2 2 2 0 YopE, N terminal SIR2 PF02146.17 EER23985.1 - 3.4e-56 190.0 0.0 5.4e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family pPIWI_RE_Y PF18156.1 EER23985.1 - 0.047 14.1 0.9 1.3 9.4 0.0 2.4 2 0 0 2 2 2 0 pPIWI_RE three-gene island domain Y T2SSF PF00482.23 EER23985.1 - 0.057 13.4 0.2 9.5 6.2 0.1 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Hexokinase_2 PF03727.16 EER23986.1 - 4.7e-81 271.8 0.0 6.1e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EER23986.1 - 2.5e-73 246.3 0.0 3.2e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Hexokinase DUF2587 PF10759.9 EER23986.1 - 0.03 13.8 0.1 0.056 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) ANAPC4_WD40 PF12894.7 EER23987.1 - 5.5e-06 26.6 0.3 2.3 8.6 0.2 4.8 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EER23987.1 - 0.00068 20.4 2.9 0.78 10.7 0.0 5.1 6 0 0 6 6 6 1 WD domain, G-beta repeat STIMATE PF12400.8 EER23988.1 - 3.2e-38 131.1 3.8 5.1e-38 130.4 3.8 1.3 1 0 0 1 1 1 1 STIMATE family Iwr1 PF08574.10 EER23988.1 - 0.079 14.0 1.3 0.12 13.4 1.3 1.3 1 0 0 1 1 1 0 Transcription factor Iwr1 RRM_1 PF00076.22 EER23989.1 - 1.3e-17 63.3 0.8 1.7e-07 30.9 0.0 2.6 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER23989.1 - 0.0068 16.0 0.1 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER23989.1 - 0.072 13.0 0.0 0.2 11.5 0.0 2.0 1 1 0 1 1 1 0 Occluded RNA-recognition motif JmjC PF02373.22 EER23990.1 - 2e-09 37.9 0.1 9.1e-09 35.8 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase JHD PF17811.1 EER23990.1 - 1.9e-08 34.8 0.4 4.3e-08 33.6 0.4 1.6 1 0 0 1 1 1 1 Jumonji helical domain PHD PF00628.29 EER23990.1 - 2.3e-08 33.8 4.7 2.3e-08 33.8 4.7 2.8 3 0 0 3 3 3 1 PHD-finger Cupin_8 PF13621.6 EER23990.1 - 8.6e-08 32.2 0.0 2.3e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.6 EER23990.1 - 0.019 14.5 4.8 0.021 14.4 2.8 2.3 2 0 0 2 2 2 0 PHD-finger Dickkopf_N PF04706.12 EER23990.1 - 0.25 11.9 9.9 4.8 7.7 0.7 3.1 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region RRM_1 PF00076.22 EER23991.1 - 6.1e-35 118.9 0.2 4.8e-16 58.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER23991.1 - 7e-11 42.1 0.3 0.00025 21.1 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 EER23991.1 - 0.01 15.9 0.0 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 EER23991.1 - 0.027 14.5 0.0 7.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Phytochelatin PF05023.14 EER23991.1 - 0.25 10.5 4.7 0.91 8.7 0.0 2.9 3 1 0 3 3 3 0 Phytochelatin synthase RabGAP-TBC PF00566.18 EER23993.1 - 4.8e-52 176.7 0.0 1.1e-51 175.5 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RrnaAD PF00398.20 EER23994.1 - 1.3e-62 211.3 0.0 1.8e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EER23994.1 - 5.5e-07 30.2 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER23994.1 - 1.5e-05 25.6 0.0 2.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EER23994.1 - 0.00034 20.4 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EER23994.1 - 0.0006 19.2 0.0 0.00089 18.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EER23994.1 - 0.00067 20.4 0.0 0.0014 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER23994.1 - 0.00097 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER23994.1 - 0.007 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EER23994.1 - 0.012 15.5 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EER23994.1 - 0.03 14.1 0.1 0.064 13.0 0.1 1.4 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.17 EER23994.1 - 0.038 13.4 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EER23994.1 - 0.052 12.8 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 EER23994.1 - 0.055 12.9 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_28 PF02636.17 EER23994.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EER23994.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRP1_N PF06424.12 EER23995.1 - 1.3e-53 181.4 7.7 3.7e-53 179.9 7.7 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 EER23995.1 - 8.5e-26 90.3 9.6 2e-07 31.4 1.8 9.6 6 3 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 EER23995.1 - 1.8e-25 87.4 35.2 8.9e-05 23.0 0.4 13.2 5 4 10 15 15 14 8 Tetratricopeptide repeat TPR_2 PF07719.17 EER23995.1 - 2.1e-11 43.0 8.7 0.21 11.8 0.0 8.2 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EER23995.1 - 1.6e-10 41.4 21.0 0.0069 17.0 0.0 7.7 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER23995.1 - 4.3e-09 35.9 1.4 1.8 9.0 0.0 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EER23995.1 - 4.2e-08 33.0 4.1 7.6 7.2 0.0 9.3 11 2 1 12 12 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER23995.1 - 2.3e-06 27.2 2.4 1.3 8.7 0.2 6.2 6 1 1 7 7 7 2 TPR repeat TPR_1 PF00515.28 EER23995.1 - 2.3e-05 24.0 1.6 0.84 9.6 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EER23995.1 - 4.9e-05 22.7 23.5 0.00025 20.4 9.5 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EER23995.1 - 0.0064 16.6 4.6 11 6.3 0.0 5.3 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.9 EER23995.1 - 0.064 12.0 4.4 3.6 6.2 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) TPR_12 PF13424.6 EER23995.1 - 0.083 13.2 4.9 26 5.2 0.1 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 EER23995.1 - 0.088 12.8 0.1 32 4.6 0.0 4.1 5 0 0 5 5 5 0 ZNRF-3 Ectodomain Cutinase PF01083.22 EER23995.1 - 0.14 12.1 0.0 1.1 9.2 0.0 2.4 1 1 1 2 2 2 0 Cutinase Suf PF05843.14 EER23995.1 - 0.42 10.5 5.3 16 5.4 0.0 3.9 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_21 PF09976.9 EER23995.1 - 3 7.5 23.1 0.21 11.3 5.0 4.5 5 1 0 5 5 5 0 Tetratricopeptide repeat-like domain SAGA-Tad1 PF12767.7 EER23996.1 - 1.2e-55 188.8 0.0 1.8e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FUSC_2 PF13515.6 EER23997.1 - 7e-33 113.5 9.3 7e-33 113.5 9.3 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EER23997.1 - 1.8e-06 26.8 11.8 0.00024 19.8 12.3 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein family ArAE_2 PF10334.9 EER23997.1 - 0.00023 21.1 0.7 0.00071 19.5 0.4 1.8 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EER23997.1 - 0.0012 17.8 11.8 0.36 9.6 0.0 3.5 3 1 0 3 3 3 2 Aluminium activated malate transporter IFT20 PF14931.6 EER23997.1 - 0.016 15.4 0.2 0.034 14.3 0.2 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 Holin_BhlA PF10960.8 EER23997.1 - 0.2 11.6 0.3 1 9.4 0.0 2.3 2 0 0 2 2 2 0 BhlA holin family ArAE_2_N PF10337.9 EER23997.1 - 0.24 10.4 2.3 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal MFS_1 PF07690.16 EER23998.1 - 3.7e-28 98.5 31.0 4.6e-27 94.9 31.0 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EER23998.1 - 9.7e-21 73.8 7.0 1.1e-20 73.6 7.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AzlD PF05437.12 EER23998.1 - 0.49 10.6 8.9 0.072 13.3 2.2 2.9 3 0 0 3 3 3 0 Branched-chain amino acid transport protein (AzlD) PGG PF13962.6 EER23998.1 - 0.7 9.7 4.1 4.5 7.1 0.8 2.8 1 1 1 2 2 2 0 Domain of unknown function PhoLip_ATPase_C PF16212.5 EER23998.1 - 1.6 8.5 8.5 0.28 10.9 3.9 1.9 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal DUF3522 PF12036.8 EER23998.1 - 4.6 7.5 6.6 1.7 8.9 2.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3522) ABC2_membrane_2 PF12679.7 EER23998.1 - 8.6 5.5 13.5 0.18 11.0 2.8 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.32 EER23999.1 - 6.2e-37 125.0 25.0 2.2e-05 25.1 0.2 10.1 9 1 1 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER23999.1 - 1.5e-22 79.6 3.2 1.2e-05 25.5 0.0 7.5 4 3 4 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EER23999.1 - 4.3e-05 23.3 1.9 13 5.9 0.0 5.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EER23999.1 - 9.1e-05 22.4 1.1 1.5 8.7 0.1 4.9 3 3 2 5 5 5 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EER23999.1 - 0.00018 20.6 3.4 7.5 5.4 0.0 5.2 5 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EER23999.1 - 0.015 14.7 1.0 35 3.6 0.0 4.1 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 EER23999.1 - 0.02 13.6 0.1 0.045 12.4 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EER23999.1 - 0.03 14.8 7.7 2.6 8.6 0.4 5.7 5 0 0 5 5 5 0 PQQ-like domain IRF PF00605.17 EER23999.1 - 0.61 10.4 2.1 1.9 8.9 0.1 2.3 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Proteasome_A_N PF10584.9 EER23999.1 - 0.68 9.7 2.3 52 3.7 0.0 3.8 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Ribosomal_S18 PF01084.20 EER24000.1 - 3.3e-16 59.2 0.0 9e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.6 EER24001.1 - 1.8e-14 53.6 0.2 0.38 11.0 0.0 6.9 6 1 1 7 7 7 5 PPR repeat family PPR PF01535.20 EER24001.1 - 5.8e-11 41.9 6.4 0.054 13.8 0.1 7.7 8 0 0 8 8 8 4 PPR repeat TPR_14 PF13428.6 EER24001.1 - 0.0093 16.7 0.2 44 5.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Glyco_hydro_67C PF07477.12 EER24001.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus ELFV_dehydrog PF00208.21 EER24002.1 - 2.7e-62 210.6 0.0 4.2e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EER24002.1 - 3.1e-16 58.2 0.0 1.9e-13 49.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EER24002.1 - 0.014 15.2 0.0 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TFIIIC_sub6 PF10419.9 EER24003.1 - 2.2e-24 85.1 0.0 4.2e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain FOG_N PF15888.5 EER24003.1 - 0.11 12.9 0.3 0.26 11.7 0.2 1.7 1 1 0 1 1 1 0 Folded gastrulation N-terminus Vps62 PF06101.11 EER24004.1 - 5.8e-12 44.7 0.3 9.4e-12 44.0 0.3 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 TRP PF06011.12 EER24005.1 - 1.3e-145 485.4 8.7 1.6e-145 485.1 8.7 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EER24005.1 - 2.5e-35 121.8 0.1 3.8e-35 121.3 0.1 1.3 1 0 0 1 1 1 1 ML-like domain HemY_N PF07219.13 EER24005.1 - 0.061 13.5 3.4 2.1 8.6 0.3 3.5 3 0 0 3 3 3 0 HemY protein N-terminus ATG22 PF11700.8 EER24006.1 - 1.8e-206 686.4 14.8 2.1e-206 686.2 14.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EER24006.1 - 3.4e-08 32.8 48.4 2.2e-05 23.5 4.0 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 EER24006.1 - 4.1e-06 25.6 24.0 9e-05 21.2 7.1 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein Phage_holin_3_6 PF07332.11 EER24006.1 - 0.055 13.5 0.1 0.055 13.5 0.1 4.5 4 1 1 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5383 PF17355.2 EER24006.1 - 0.18 12.2 0.4 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5383) Actin PF00022.19 EER24007.1 - 1.6e-141 471.6 0.0 1.8e-141 471.4 0.0 1.0 1 0 0 1 1 1 1 Actin Hep_59 PF07052.11 EER24008.1 - 9.2e-17 61.7 0.1 9.2e-17 61.7 0.1 2.2 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 Methyltransf_16 PF10294.9 EER24009.1 - 7.4e-43 146.3 0.0 9.9e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EER24009.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 EER24009.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Mpp10 PF04006.12 EER24010.1 - 9e-113 377.9 36.8 4.1e-112 375.7 36.8 1.8 1 1 0 1 1 1 1 Mpp10 protein RskA PF10099.9 EER24011.1 - 0.00032 21.1 0.1 0.00044 20.6 0.1 1.2 1 0 0 1 1 1 1 Anti-sigma-K factor rskA CI-B14_5a PF07347.12 EER24011.1 - 0.05 13.5 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) AhpC-TSA PF00578.21 EER24012.1 - 1.2e-23 83.3 0.0 1.8e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EER24012.1 - 2.2e-15 56.7 0.0 2.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EER24012.1 - 4.7e-05 23.5 0.0 9.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AbfS_sensor PF18225.1 EER24012.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain DUF3987 PF13148.6 EER24012.1 - 0.5 9.3 2.7 0.66 8.9 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tim54 PF11711.8 EER24012.1 - 1.1 8.0 4.2 1.3 7.7 4.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CH PF00307.31 EER24013.1 - 5e-74 245.5 0.0 8e-20 71.1 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EER24013.1 - 2e-06 28.1 0.8 1.5e-05 25.3 0.3 2.5 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.8 EER24013.1 - 0.00025 20.8 0.0 0.65 9.9 0.0 3.9 4 0 0 4 4 4 1 CAMSAP CH domain EF-hand_6 PF13405.6 EER24013.1 - 0.002 17.9 2.3 0.048 13.6 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EER24013.1 - 0.0033 16.9 0.3 1.5 8.6 0.0 3.5 3 0 0 3 3 3 1 EF hand HD PF01966.22 EER24014.1 - 1.3e-05 25.5 0.0 1.8e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 HD domain DSPc PF00782.20 EER24015.1 - 4.6e-25 88.0 0.0 6.4e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EER24015.1 - 0.0025 17.4 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EER24015.1 - 0.19 12.0 0.0 0.33 11.3 0.0 1.4 1 0 0 1 1 1 0 Rit1 DUSP-like domain PC4 PF02229.16 EER24016.1 - 1.6e-24 85.3 0.1 2.4e-24 84.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.14 EER24017.1 - 2.6e-225 748.7 0.0 3.9e-225 748.1 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EER24017.1 - 1.5e-103 346.1 1.1 2.3e-103 345.4 0.2 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EER24017.1 - 2.9e-61 206.3 0.6 1.9e-59 200.3 0.0 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region ArAE_1_C PF11728.8 EER24017.1 - 0.11 12.5 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain MIT PF04212.18 EER24018.1 - 3.9e-15 55.7 1.6 8.9e-15 54.5 0.6 2.2 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Totivirus_coat PF05518.11 EER24018.1 - 4 5.4 11.9 6.9 4.6 11.9 1.3 1 0 0 1 1 1 0 Totivirus coat protein Ald_Xan_dh_C2 PF02738.18 EER24019.1 - 0.1 11.1 0.8 0.19 10.1 0.8 1.3 1 0 0 1 1 1 0 Molybdopterin-binding domain of aldehyde dehydrogenase DUF4795 PF16043.5 EER24019.1 - 0.74 9.4 33.1 1.4 8.5 10.1 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4795) CNDH2_C PF16858.5 EER24019.1 - 0.81 9.5 14.8 0.036 13.9 5.9 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term OmpH PF03938.14 EER24019.1 - 6.6 7.1 19.0 1 9.7 8.2 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) PIN_8 PF18476.1 EER24019.1 - 9.9 5.9 20.2 4 7.2 6.7 3.6 2 1 1 3 3 3 0 PIN like domain Na_Ca_ex PF01699.24 EER24020.1 - 1.1e-22 80.6 27.3 1.2e-12 48.1 6.2 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Nup96 PF12110.8 EER24020.1 - 0.18 10.9 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear protein 96 DUF4131 PF13567.6 EER24020.1 - 0.25 11.0 7.2 41 3.8 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PALP PF00291.25 EER24021.1 - 2.3e-65 220.9 0.1 3.3e-65 220.4 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EER24021.1 - 9.7e-13 48.4 0.1 3.5e-08 33.8 0.0 3.0 3 0 0 3 3 3 2 CBS domain SRPRB PF09439.10 EER24022.1 - 7.6e-23 80.9 0.3 7.4e-18 64.6 0.2 2.5 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 EER24022.1 - 0.00014 21.3 0.2 0.0014 18.1 0.2 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 EER24022.1 - 0.0033 17.8 0.1 0.0078 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EER24022.1 - 0.0046 16.4 0.0 0.0094 15.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EER24022.1 - 0.0093 16.4 0.3 0.03 14.8 0.3 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EER24022.1 - 0.013 15.8 0.2 0.076 13.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EER24022.1 - 0.019 14.8 0.1 3.8 7.2 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 EER24022.1 - 0.077 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EER24022.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 EER24022.1 - 0.14 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EER24022.1 - 0.17 11.3 0.0 0.48 9.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region GPI-anchored PF10342.9 EER24023.1 - 1e-13 51.8 0.0 1.9e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.11 EER24023.1 - 1.4e-11 45.0 1.0 1.4e-11 45.0 1.0 1.6 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.28 EER24024.1 - 1.4e-41 142.6 1.5 2e-41 142.2 1.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EER24024.1 - 1.5e-17 63.3 0.5 7.9e-17 61.0 0.1 2.2 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.9 EER24025.1 - 5.4e-74 247.6 5.4 6.7e-74 247.3 5.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EER24025.1 - 0.00097 19.0 2.3 0.0011 18.8 1.2 1.6 1 1 0 1 1 1 1 SprT-like family Peptidase_M13 PF01431.21 EER24025.1 - 0.013 15.1 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M13 Peptidase_M91 PF14891.6 EER24025.1 - 0.013 15.8 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 0 Effector protein Tox-MPTase2 PF15638.6 EER24025.1 - 0.03 14.0 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Pkinase PF00069.25 EER24026.1 - 1.1e-69 234.7 0.0 1.4e-69 234.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24026.1 - 6.2e-41 140.4 0.0 8.1e-41 140.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER24026.1 - 3e-05 23.5 0.0 8.6e-05 22.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EER24026.1 - 0.0002 20.8 0.1 0.00031 20.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EER24026.1 - 0.0016 17.5 0.0 0.0022 17.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EER24026.1 - 0.069 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EER24026.1 - 0.08 12.6 0.1 0.17 11.5 0.0 1.6 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EER24026.1 - 0.085 12.8 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EER24026.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TIP41 PF04176.13 EER24027.1 - 1.1e-72 243.0 0.0 1.4e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.12 EER24028.1 - 1.7e-35 122.2 0.0 2.1e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF1143 PF06608.11 EER24028.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1143) Peptidase_M24 PF00557.24 EER24030.1 - 2.8e-55 187.2 0.0 6.3e-55 186.1 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.16 EER24030.1 - 9.1e-25 86.8 0.0 2e-24 85.7 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF2183 PF09949.9 EER24032.1 - 5.3e-21 74.8 0.1 1e-20 73.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF4306 PF14154.6 EER24032.1 - 0.095 12.9 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4306) Cyclin PF08613.11 EER24033.1 - 3.3e-34 118.6 0.0 4.2e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EER24033.1 - 0.032 14.0 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ank_2 PF12796.7 EER24034.1 - 1.6e-27 95.9 0.0 1.3e-11 44.9 0.0 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER24034.1 - 3.8e-26 90.8 0.5 3e-08 33.7 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER24034.1 - 1.8e-23 80.1 2.4 9.2e-07 28.7 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EER24034.1 - 4.1e-21 74.4 0.1 8.6e-06 26.0 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EER24034.1 - 3.9e-20 71.9 0.3 4e-08 33.6 0.1 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 EER24034.1 - 3.5e-12 46.6 15.5 5.5e-09 36.2 8.3 3.7 3 1 0 3 3 3 2 DHHC palmitoyltransferase K_oxygenase PF13434.6 EER24035.1 - 7.8e-111 370.5 0.0 9.3e-111 370.2 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EER24035.1 - 7.5e-09 35.2 0.0 5.7e-07 29.1 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER24035.1 - 7.8e-05 22.7 0.0 0.0036 17.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EER24035.1 - 0.00019 20.8 0.0 0.0016 17.8 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase PARP_regulatory PF01358.18 EER24035.1 - 0.052 12.5 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit AMP-binding PF00501.28 EER24036.1 - 4.8e-228 756.8 0.0 6e-79 265.6 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EER24036.1 - 2e-164 547.6 0.0 2.8e-37 128.5 0.1 8.1 6 3 0 6 6 6 6 Condensation domain PP-binding PF00550.25 EER24036.1 - 6.2e-60 199.5 14.1 6.6e-11 42.4 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EER24036.1 - 2.1e-13 51.0 0.0 1.8e-07 32.0 0.0 3.8 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Aldolase PF01081.19 EER24036.1 - 0.14 11.6 0.2 19 4.6 0.1 2.5 2 0 0 2 2 2 0 KDPG and KHG aldolase Pkinase PF00069.25 EER24037.1 - 2.4e-39 135.3 0.0 7.6e-38 130.4 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24037.1 - 6e-23 81.4 0.0 8.8e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OB_NTP_bind PF07717.16 EER24038.1 - 2.3e-23 82.3 0.0 4.8e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EER24038.1 - 1.4e-19 70.3 0.0 1.4e-19 70.3 0.0 4.1 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EER24038.1 - 3.4e-13 49.9 0.0 8.3e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EER24038.1 - 2.6e-06 27.3 0.1 8.4e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EER24038.1 - 2.7e-05 24.4 0.2 0.0002 21.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EER24038.1 - 0.00025 20.8 0.1 0.00062 19.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EER24038.1 - 0.00038 19.6 0.0 0.00076 18.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PWI PF01480.17 EER24038.1 - 0.00042 20.6 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 PWI domain AAA_19 PF13245.6 EER24038.1 - 0.001 19.4 0.1 0.0022 18.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EER24038.1 - 0.0025 17.5 0.3 0.0065 16.1 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.6 EER24038.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 EER24038.1 - 0.11 12.9 0.1 0.11 12.9 0.1 3.9 2 1 2 4 4 1 0 AAA domain ABC_tran PF00005.27 EER24038.1 - 1.8 9.1 5.7 0.32 11.5 0.2 2.6 1 1 1 2 2 2 0 ABC transporter AAA PF00004.29 EER24039.1 - 7.6e-12 45.8 0.0 1.3e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EER24039.1 - 0.0035 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF3201 PF11447.8 EER24039.1 - 0.076 12.5 0.0 0.17 11.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) Mgm101p PF06420.12 EER24039.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Pkinase PF00069.25 EER24040.1 - 5.1e-17 62.1 0.0 3e-07 30.1 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER24040.1 - 3.3e-09 36.4 0.0 0.0017 17.7 0.0 3.5 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.6 EER24040.1 - 0.0018 17.7 0.0 0.11 11.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Cyt-b5 PF00173.28 EER24041.1 - 3.2e-21 75.3 0.2 3.6e-21 75.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.8 EER24041.1 - 0.032 14.3 0.0 0.052 13.7 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H DUF4291 PF14124.6 EER24042.1 - 1.3e-71 240.2 0.1 1.5e-71 240.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Mcp5_PH PF12814.7 EER24043.1 - 3.3e-44 149.9 0.1 7.1e-44 148.8 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EER24043.1 - 1.9e-05 25.2 16.2 1.9e-05 25.2 16.2 1.8 2 0 0 2 2 2 1 Fez1 CENP-F_leu_zip PF10473.9 EER24043.1 - 0.0026 17.8 16.9 0.0049 16.9 16.9 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EER24043.1 - 0.0036 17.4 23.2 0.77 9.8 17.5 2.6 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 EER24043.1 - 0.052 13.4 12.3 0.021 14.7 9.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) UPF0242 PF06785.11 EER24043.1 - 0.25 11.4 13.2 0.62 10.1 13.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EER24043.1 - 0.69 9.4 8.2 1.6 8.3 8.2 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4200 PF13863.6 EER24043.1 - 2.8 8.4 16.3 6.3 7.2 16.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) KxDL PF10241.9 EER24043.1 - 9 6.7 8.4 11 6.4 4.3 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein GST_C_2 PF13410.6 EER24044.1 - 2.1e-16 59.7 0.0 3.5e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EER24044.1 - 5.8e-11 42.5 0.0 1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EER24044.1 - 8.3e-07 29.1 0.0 1.5e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EER24044.1 - 3.9e-05 23.8 0.0 7.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EER24044.1 - 0.081 13.5 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ras PF00071.22 EER24045.1 - 2.8e-50 170.1 0.1 2.3e-49 167.1 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EER24045.1 - 3.2e-18 66.1 1.1 6.7e-17 61.8 0.1 2.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER24045.1 - 0.00087 18.8 0.0 0.0032 16.9 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_25 PF13481.6 EER24045.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.28 EER24046.1 - 1.4e-77 261.1 0.0 1.6e-77 260.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EER24046.1 - 3.1e-17 62.2 0.1 7.2e-17 61.1 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EER24046.1 - 1.2e-15 58.2 0.0 1.1e-14 55.2 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.16 EER24047.1 - 3.9e-35 121.4 28.9 5.2e-35 121.0 28.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily SHMT PF00464.19 EER24049.1 - 9e-199 660.1 0.0 1e-198 659.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EER24049.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MOSC PF03473.17 EER24050.1 - 1.3e-32 112.6 0.0 2.6e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EER24050.1 - 2.5e-16 59.6 0.0 4.4e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Patatin PF01734.22 EER24051.1 - 8.7e-14 52.2 0.0 2.1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase OTT_1508_deam PF14441.6 EER24052.1 - 2e-07 30.9 0.1 3.9e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Mg_trans_NIPA PF05653.14 EER24053.1 - 1.9e-88 296.4 26.7 2.6e-88 295.9 26.7 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EER24053.1 - 8.4e-05 22.8 6.2 8.4e-05 22.8 6.2 3.2 3 0 0 3 3 3 1 EamA-like transporter family BCLP PF12304.8 EER24053.1 - 0.083 12.4 9.4 0.062 12.8 1.8 2.7 3 0 0 3 3 3 0 Beta-casein like protein Zn_clus PF00172.18 EER24054.1 - 1e-09 38.4 11.6 1.9e-09 37.5 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPESP1 PF15754.5 EER24055.1 - 0.025 13.8 0.2 0.036 13.3 0.2 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Gcn1_N PF12074.8 EER24056.1 - 1.6e-117 392.8 6.0 8.2e-117 390.5 0.4 3.3 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 EER24056.1 - 9.4e-60 200.8 6.8 9.4e-60 200.8 6.8 1.9 2 0 0 2 2 1 1 Ribosomal protein L19e HEAT_2 PF13646.6 EER24056.1 - 1e-23 83.5 35.9 4.3e-05 23.8 0.0 13.9 10 5 3 14 14 14 7 HEAT repeats HEAT PF02985.22 EER24056.1 - 2.9e-22 76.8 41.6 0.11 12.8 0.1 21.0 26 0 0 26 26 24 6 HEAT repeat HEAT_EZ PF13513.6 EER24056.1 - 3.2e-21 75.4 34.0 8.9e-06 26.1 0.0 19.3 19 3 1 20 20 19 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EER24056.1 - 4.6e-13 49.6 0.0 1.1 9.9 0.0 8.5 6 2 1 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EER24056.1 - 1.8e-12 47.6 4.4 0.044 13.8 0.1 8.3 7 1 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EER24056.1 - 4.9e-07 30.0 3.5 1.6 8.9 0.0 6.9 6 1 0 6 6 6 2 Parkin co-regulated protein TIP120 PF08623.10 EER24056.1 - 0.00057 19.7 7.2 0.024 14.4 0.0 5.4 6 0 0 6 6 5 1 TATA-binding protein interacting (TIP20) Ecm29 PF13001.7 EER24056.1 - 0.0011 17.7 0.8 0.7 8.5 0.0 4.1 4 0 0 4 4 4 1 Proteasome stabiliser RTP1_C1 PF10363.9 EER24056.1 - 0.035 14.3 5.1 14 5.9 0.0 6.4 7 0 0 7 7 6 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF937 PF06078.11 EER24056.1 - 0.33 11.6 7.6 23 5.6 0.0 5.0 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF937) Cohesin_HEAT PF12765.7 EER24056.1 - 0.47 10.8 5.1 27 5.2 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HA2 PF04408.23 EER24057.1 - 1.2e-17 64.1 0.1 4.1e-17 62.4 0.1 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EER24057.1 - 6.6e-12 45.5 0.0 1.3e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER24057.1 - 2e-11 44.2 0.1 5.3e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EER24057.1 - 2.7e-06 27.6 0.0 5.7e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 EER24057.1 - 5.1e-06 26.8 0.3 1.8e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain RuvA_C PF07499.13 EER24057.1 - 0.28 11.7 1.2 2 9.0 0.0 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain KilA-N PF04383.13 EER24058.1 - 0.00018 21.3 0.0 0.0042 16.9 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain BRCT_2 PF16589.5 EER24059.1 - 1.7e-08 34.8 0.0 2.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EER24059.1 - 0.00044 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EER24059.1 - 0.002 18.0 0.2 0.004 17.1 0.0 1.6 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 EER24059.1 - 0.04 14.2 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain adh_short PF00106.25 EER24060.1 - 4.5e-41 140.5 0.4 2.5e-40 138.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER24060.1 - 1.7e-28 99.8 0.0 2.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER24060.1 - 1.5e-10 41.2 0.7 6.1e-09 36.0 0.7 2.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EER24060.1 - 0.0083 15.6 0.0 0.018 14.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3216 PF11505.8 EER24060.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) V_ATPase_I PF01496.19 EER24061.1 - 0.0031 15.5 13.9 0.01 13.8 13.9 1.9 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CorA PF01544.18 EER24062.1 - 2.3e-39 135.5 0.1 3.6e-39 134.8 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.7 EER24063.1 - 1.8e-147 491.8 1.7 1.9e-147 491.7 0.0 1.9 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 DUF3824 PF12868.7 EER24064.1 - 8.6e-26 91.4 135.5 2.7e-24 86.5 54.4 8.5 3 3 3 7 7 7 4 Domain of unknwon function (DUF3824) ABA_WDS PF02496.16 EER24064.1 - 0.0078 16.7 26.0 0.054 14.0 0.5 5.8 4 2 1 5 5 5 2 ABA/WDS induced protein NDUF_B12 PF08122.12 EER24064.1 - 0.038 14.0 0.5 0.62 10.2 0.0 2.8 3 1 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF2637 PF10935.8 EER24064.1 - 0.77 9.6 3.0 0.56 10.1 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2637) Ribosomal_L44 PF00935.19 EER24065.1 - 3.2e-36 123.7 11.6 5.2e-36 123.0 11.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.23 EER24066.1 - 1.3e-25 88.9 0.0 1.5e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EER24066.1 - 2.6e-15 56.0 0.1 2.8e-15 55.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EER24066.1 - 0.00032 21.1 0.0 0.0012 19.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EER24066.1 - 0.0085 16.0 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Elongin_A PF06881.11 EER24067.1 - 1.8e-28 99.1 0.0 3.1e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Sugar_tr PF00083.24 EER24069.1 - 7e-72 242.7 20.6 3.7e-70 237.0 20.6 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER24069.1 - 1.6e-05 24.0 35.3 2.9e-05 23.2 30.4 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily EBP PF05241.12 EER24069.1 - 0.89 9.0 7.5 0.4 10.1 1.9 2.4 2 0 0 2 2 2 0 Emopamil binding protein Hemerythrin PF01814.23 EER24070.1 - 8.4e-10 39.4 4.7 1.1e-09 39.0 4.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Band_7 PF01145.25 EER24071.1 - 1.1e-16 61.3 0.1 1.1e-16 61.3 0.1 2.5 2 1 0 2 2 2 1 SPFH domain / Band 7 family PCEMA1 PF07418.11 EER24071.1 - 0.64 9.5 8.2 1.1 8.7 8.2 1.4 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 TBCA PF02970.16 EER24073.1 - 4.6e-15 55.7 10.4 2e-14 53.7 8.4 2.0 1 1 1 2 2 2 2 Tubulin binding cofactor A Aldedh PF00171.22 EER24073.1 - 0.091 11.3 0.8 0.13 10.7 0.8 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family V_ATPase_I PF01496.19 EER24073.1 - 1.9 6.3 4.1 2.2 6.1 4.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family THOC7 PF05615.13 EER24074.1 - 9.4e-47 158.6 5.8 9.4e-47 158.6 5.8 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 Peroxin-13_N PF04088.13 EER24074.1 - 0.013 15.8 0.4 0.028 14.7 0.4 1.6 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Mod_r PF07200.13 EER24074.1 - 0.021 14.9 13.3 0.044 13.9 13.3 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DUF1843 PF08898.10 EER24074.1 - 0.093 13.3 0.2 0.093 13.3 0.2 2.4 2 1 2 4 4 4 0 Domain of unknown function (DUF1843) Fer4_NifH PF00142.18 EER24074.1 - 0.16 11.4 0.7 0.23 10.9 0.7 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family FUSC PF04632.12 EER24074.1 - 0.28 9.7 7.7 0.36 9.3 7.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FlxA PF14282.6 EER24074.1 - 0.91 9.6 8.6 0.18 11.8 4.4 2.0 2 0 0 2 2 2 0 FlxA-like protein CENP-H PF05837.12 EER24074.1 - 2.1 8.8 12.0 1.6 9.2 9.9 1.9 1 1 0 1 1 1 0 Centromere protein H (CENP-H) TMPIT PF07851.13 EER24074.1 - 2.3 7.4 6.0 3.4 6.8 6.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 EER24074.1 - 2.4 7.0 4.8 3 6.6 4.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 EER24074.1 - 2.5 6.6 12.0 12 4.3 11.7 1.9 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF2175 PF09943.9 EER24074.1 - 3 8.2 4.8 3.7 7.9 3.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) 5_nucleotid PF05761.14 EER24074.1 - 8.5 5.2 7.1 9.2 5.0 4.9 1.8 1 1 1 2 2 2 0 5' nucleotidase family PTR2 PF00854.21 EER24075.1 - 7.4e-82 275.3 0.9 4.6e-40 137.7 0.1 2.1 1 1 1 2 2 2 2 POT family CCB1 PF12046.8 EER24075.1 - 0.013 14.8 0.1 0.029 13.7 0.1 1.5 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF5392 PF17370.2 EER24075.1 - 0.96 9.5 2.4 0.97 9.5 0.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5392) AA_permease PF00324.21 EER24076.1 - 5e-125 417.8 40.5 6.1e-125 417.5 40.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER24076.1 - 1.4e-40 139.4 41.2 1.9e-40 139.0 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease Malic_M PF03949.15 EER24077.1 - 1.9e-89 299.4 0.0 2.3e-89 299.1 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EER24077.1 - 5.6e-62 208.8 0.0 9.2e-62 208.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.6 EER24078.1 - 3.5e-08 33.7 6.9 7.6e-07 29.4 0.0 3.4 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) GrpE PF01025.19 EER24078.1 - 0.0086 15.8 0.3 3 7.5 0.2 2.6 2 0 0 2 2 2 2 GrpE DUF3887 PF13026.6 EER24078.1 - 0.012 16.4 1.9 2.9 8.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3887) YtxH PF12732.7 EER24078.1 - 1.1 9.8 7.5 6.5 7.4 0.1 3.4 3 0 0 3 3 3 0 YtxH-like protein TipAS PF07739.13 EER24078.1 - 1.3 9.6 5.1 3.6 8.1 0.2 3.6 3 1 2 5 5 5 0 TipAS antibiotic-recognition domain HIP1_clath_bdg PF16515.5 EER24078.1 - 4.3 8.0 6.7 5.5 7.7 2.0 3.1 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DnaJ_C PF01556.18 EER24079.1 - 2.1e-26 92.8 0.0 3e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EER24079.1 - 2e-25 88.7 2.2 3.3e-25 88.0 2.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EER24079.1 - 1.9e-14 53.8 15.6 3.2e-14 53.0 15.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EER24079.1 - 5.8e-07 29.4 8.6 0.0015 18.5 1.9 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EER24079.1 - 0.0052 16.8 6.9 0.74 9.9 1.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EER24079.1 - 0.27 10.9 6.8 0.26 11.0 0.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 EER24079.1 - 0.35 11.3 10.6 0.61 10.5 1.3 2.9 2 1 1 3 3 3 0 Restriction alleviation protein Lar DZR PF12773.7 EER24079.1 - 5.7 7.0 11.9 1.1e+02 2.9 11.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon S4 PF01479.25 EER24080.1 - 2.5e-12 46.3 0.1 4.1e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EER24080.1 - 2.2e-10 41.3 2.5 3.3e-10 40.7 2.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Speriolin_C PF15059.6 EER24080.1 - 0.022 14.9 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 Speriolin C-terminus MFS_1 PF07690.16 EER24082.1 - 3.5e-33 115.0 29.9 4.4e-33 114.7 28.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily OMPdecase PF00215.24 EER24083.1 - 6.5e-76 254.9 0.0 7.4e-76 254.7 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.18 EER24084.1 - 1.3e-23 83.4 2.5 1.5e-23 83.1 2.5 1.0 1 0 0 1 1 1 1 MAPEG family DUF997 PF06196.12 EER24084.1 - 0.007 16.3 1.4 0.013 15.5 1.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF997) DUF2627 PF11118.8 EER24084.1 - 0.0087 16.6 0.5 0.067 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2627) MBOAT PF03062.19 EER24085.1 - 2.6e-24 86.2 16.3 4e-24 85.6 16.3 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EER24085.1 - 0.0017 18.6 2.2 0.0046 17.2 2.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 EER24086.1 - 1.5e-31 107.9 30.2 2.8e-06 27.9 1.6 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER24086.1 - 3.2e-17 62.6 0.2 0.00072 19.8 0.0 5.5 2 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER24086.1 - 0.0012 18.8 0.2 0.84 9.5 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Bacteroid_pep PF14406.6 EER24086.1 - 0.21 12.0 0.0 0.52 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Tmemb_170 PF10190.9 EER24087.1 - 7.2e-24 84.2 13.1 8.1e-24 84.0 13.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 Comm PF15957.5 EER24087.1 - 0.92 9.9 3.9 1.7 9.0 3.9 1.5 1 0 0 1 1 1 0 Commissureless ICMT PF04140.14 EER24089.1 - 4.2e-25 88.0 0.7 4.2e-25 88.0 0.7 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EER24089.1 - 5.2e-10 39.7 2.1 5.2e-10 39.7 2.1 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EER24089.1 - 0.00018 21.1 0.4 0.00033 20.3 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 EER24089.1 - 0.0042 16.6 0.8 0.0042 16.6 0.8 2.0 1 1 0 2 2 2 1 NnrU protein Hexapep PF00132.24 EER24090.1 - 1.4e-13 50.0 13.5 3.2e-11 42.5 6.0 3.2 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EER24090.1 - 3.2e-13 49.7 0.1 5.9e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EER24090.1 - 1.6e-11 43.7 11.4 2e-10 40.2 4.5 3.1 2 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF3517 PF12030.8 EER24091.1 - 6.4e-102 340.9 0.0 1e-101 340.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.29 EER24091.1 - 1.1e-39 136.5 0.1 2.8e-39 135.2 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER24091.1 - 3.4e-24 86.0 0.1 8.3e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Hs1pro-1_C PF07014.12 EER24091.1 - 0.079 12.4 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus TrkH PF02386.16 EER24092.1 - 1.5e-129 432.7 5.7 1.7e-126 422.7 3.1 2.0 2 0 0 2 2 2 2 Cation transport protein TFIIE_alpha PF02002.17 EER24093.1 - 4.4e-19 68.3 0.0 8e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit PseudoU_synth_1 PF01416.20 EER24094.1 - 6.6e-10 39.4 0.0 1.7e-08 34.8 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridine synthase PH PF00169.29 EER24095.1 - 1.8e-07 31.6 0.0 6.8e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 PH domain Anillin PF08174.11 EER24095.1 - 1e-06 29.2 0.2 3.3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Cell division protein anillin NYN_YacP PF05991.11 EER24095.1 - 0.028 14.4 1.0 0.075 13.0 0.1 2.2 2 0 0 2 2 2 0 YacP-like NYN domain DEAD PF00270.29 EER24096.1 - 1.8e-34 119.0 0.0 3.3e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER24096.1 - 1.5e-20 73.6 0.0 6.3e-18 65.1 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EER24096.1 - 6.2e-05 23.1 0.0 0.001 19.1 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RNase_H2-Ydr279 PF09468.10 EER24096.1 - 3.1 8.0 5.2 7.4 6.7 0.4 2.8 2 1 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) wHTH domain SET PF00856.28 EER24097.1 - 8.1e-11 42.6 0.0 3e-10 40.8 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF3283 PF11686.8 EER24097.1 - 0.5 10.3 2.4 0.66 9.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3283) Ribosomal_L14 PF00238.19 EER24098.1 - 1.5e-44 150.9 1.3 1.9e-44 150.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TFIIS_C PF01096.18 EER24099.1 - 6.1e-15 54.8 3.0 6.1e-15 54.8 3.0 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EER24099.1 - 2.5e-11 43.2 0.8 2.5e-11 43.2 0.8 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 EER24099.1 - 0.019 15.3 9.3 0.3 11.4 0.6 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 EER24099.1 - 0.14 12.2 12.4 2.6e+02 1.7 12.4 2.6 1 1 0 1 1 1 0 Double zinc ribbon Lar_restr_allev PF14354.6 EER24099.1 - 0.48 10.8 10.9 0.091 13.2 2.4 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf_C2H2_13 PF18508.1 EER24099.1 - 2 8.1 7.6 36 4.0 0.8 3.3 3 0 0 3 3 3 0 Zinc finger domain Rotamase PF00639.21 EER24100.1 - 1.2e-22 80.7 0.0 1.6e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EER24100.1 - 3.9e-17 62.8 0.0 5.1e-17 62.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EER24100.1 - 1.6e-09 37.7 3.3 1.6e-09 37.7 3.3 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EER24100.1 - 0.00036 21.4 0.0 0.00049 20.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW_1 PF18507.1 EER24100.1 - 0.14 11.9 1.1 0.23 11.2 1.1 1.4 1 0 0 1 1 1 0 WW domain RRM_1 PF00076.22 EER24103.1 - 5.2e-15 55.0 0.0 7.2e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.19 EER24104.1 - 1.2e-55 188.3 0.0 6.3e-44 150.1 0.0 2.2 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EER24104.1 - 7.5e-10 38.7 0.0 1.4e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EER24104.1 - 1.1e-05 25.2 0.0 4.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 EER24104.1 - 0.0049 16.5 0.0 0.0073 16.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EER24104.1 - 0.0097 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ACPS PF01648.20 EER24105.1 - 3.2e-13 49.8 0.0 1.2e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.21 EER24106.1 - 2.7e-32 111.2 0.0 4.1e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.28 EER24107.1 - 2e-39 131.8 9.2 5.7e-08 32.3 0.0 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 EER24107.1 - 7.3e-34 113.2 16.3 2e-05 24.4 0.0 9.3 10 0 0 10 10 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EER24107.1 - 4.5e-33 113.3 11.8 3.5e-24 84.8 0.1 4.6 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EER24107.1 - 3.3e-26 89.2 7.2 0.0012 18.9 0.0 8.4 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_11 PF13414.6 EER24107.1 - 3.3e-25 87.5 5.7 2.8e-05 23.7 0.9 8.6 7 1 2 9 9 9 6 TPR repeat TPR_14 PF13428.6 EER24107.1 - 9.2e-21 72.8 1.8 0.045 14.6 0.0 9.3 5 1 3 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 EER24107.1 - 7.4e-20 71.2 3.2 0.0046 17.4 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EER24107.1 - 1.7e-18 66.7 8.1 0.00063 20.0 0.0 7.4 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EER24107.1 - 1.3e-15 56.6 3.6 2.5 8.7 0.0 9.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER24107.1 - 3.5e-12 45.4 0.8 0.011 15.6 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EER24107.1 - 4.5e-12 46.4 9.0 0.0021 18.7 0.0 7.6 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EER24107.1 - 2.8e-07 30.7 7.5 1.3 9.8 0.1 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EER24107.1 - 5e-06 26.2 1.6 0.014 15.3 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 EER24107.1 - 0.00034 19.9 0.3 0.38 9.9 0.1 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EER24107.1 - 0.00083 19.5 0.0 5.8 7.1 0.0 4.6 2 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 EER24107.1 - 0.025 13.6 0.0 3.1 6.7 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF5331 PF17265.2 EER24107.1 - 0.12 12.1 0.0 8 6.2 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5331) TPR_4 PF07721.14 EER24107.1 - 0.59 10.9 2.3 2.4e+02 2.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.8 EER24107.1 - 0.68 8.8 5.8 9.6 5.0 0.1 3.5 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 EER24107.1 - 0.75 9.5 4.4 3.3 7.4 0.3 3.3 3 1 0 4 4 4 0 Tetratricopeptide repeat-like domain F-box PF00646.33 EER24108.1 - 1.6e-08 34.2 0.5 5.7e-08 32.4 0.5 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EER24108.1 - 5.5e-06 26.2 0.1 5.5e-06 26.2 0.1 2.5 3 0 0 3 3 3 1 F-box-like F-box_4 PF15966.5 EER24108.1 - 0.029 14.2 0.0 0.065 13.1 0.0 1.7 1 0 0 1 1 1 0 F-box PRANC PF09372.10 EER24108.1 - 0.058 13.7 0.0 6.4 7.2 0.0 2.3 2 0 0 2 2 2 0 PRANC domain Phage_min_cap2 PF06152.11 EER24109.1 - 1.7 7.4 8.0 0.44 9.4 1.5 2.2 2 0 0 2 2 2 0 Phage minor capsid protein 2 RINGv PF12906.7 EER24110.1 - 2.4e-16 59.6 8.7 4e-16 58.9 8.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EER24110.1 - 0.0011 19.2 7.6 0.002 18.4 7.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 EER24110.1 - 0.57 10.0 6.5 0.95 9.3 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EER24110.1 - 2.7 7.9 4.6 6.9 6.6 4.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EER24110.1 - 4.3 7.6 5.9 9.4 6.5 5.9 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain HeLo PF14479.6 EER24111.1 - 0.00014 21.8 1.2 0.0035 17.2 1.2 2.2 1 1 0 1 1 1 1 Prion-inhibition and propagation Trypsin_2 PF13365.6 EER24111.1 - 0.0036 18.2 0.1 0.0087 17.0 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain ACC_central PF08326.12 EER24112.1 - 1.3e-285 949.4 0.0 1.6e-285 949.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EER24112.1 - 1.3e-189 631.0 0.0 2.5e-189 630.1 0.0 1.5 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EER24112.1 - 4.8e-52 176.5 0.0 9e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EER24112.1 - 1.5e-27 96.3 0.0 2.9e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EER24112.1 - 1.4e-22 79.8 0.0 6.4e-20 71.3 0.0 3.1 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EER24112.1 - 1.1e-14 54.0 0.1 3.2e-14 52.5 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EER24112.1 - 0.00082 19.5 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EER24112.1 - 0.0038 16.8 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EER24112.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.6 EER24112.1 - 0.17 11.7 0.1 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 Biotin-lipoyl like NUDE_C PF04880.13 EER24113.1 - 1.5e-61 207.9 11.1 1.5e-61 207.9 11.1 4.1 2 2 2 5 5 3 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 EER24113.1 - 1.7e-05 25.1 7.5 1.7e-05 25.1 7.5 4.6 2 1 2 4 4 3 2 Cell division protein ZapB ATG16 PF08614.11 EER24113.1 - 0.099 12.9 36.4 0.02 15.1 17.7 3.1 2 1 1 3 3 2 0 Autophagy protein 16 (ATG16) Speriolin_C PF15059.6 EER24113.1 - 0.1 12.7 1.3 0.19 11.9 1.3 1.4 1 0 0 1 1 1 0 Speriolin C-terminus HEPN_DZIP3 PF18738.1 EER24113.1 - 0.14 11.9 2.2 0.26 11.1 2.2 1.4 1 0 0 1 1 1 0 DZIP3/ hRUL138-like HEPN DivIC PF04977.15 EER24113.1 - 0.2 11.4 25.3 0.27 11.0 2.7 4.1 3 1 1 4 4 4 0 Septum formation initiator Fez1 PF06818.15 EER24113.1 - 0.41 11.1 24.4 0.74 10.2 13.6 2.5 1 1 1 2 2 2 0 Fez1 PRKG1_interact PF15898.5 EER24113.1 - 0.59 11.1 21.9 0.31 12.0 12.0 2.9 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain APG6_N PF17675.1 EER24113.1 - 1.2 9.7 34.3 0.53 10.8 6.8 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF4201 PF13870.6 EER24113.1 - 2.1 8.1 21.8 0.3 10.8 1.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 EER24113.1 - 5.3 5.8 27.5 2.2 7.1 5.8 2.7 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 EER24113.1 - 6.8 6.8 28.8 1.2 9.2 3.1 3.5 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.12 EER24113.1 - 8.2 6.5 33.1 1 9.5 8.4 3.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 EER24113.1 - 8.8 5.6 28.8 9.6 5.5 17.6 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Isochorismatase PF00857.20 EER24114.1 - 1.9e-39 135.7 0.0 2.9e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Sedlin_N PF04628.13 EER24115.1 - 2.7e-42 144.0 0.0 3.1e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EER24115.1 - 3.6e-05 23.7 0.0 0.0013 18.7 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family DUF2040 PF09745.9 EER24116.1 - 3.5e-37 127.1 14.2 3.5e-37 127.1 14.2 4.3 3 1 0 3 3 3 1 Coiled-coil domain-containing protein 55 (DUF2040) Zip PF02535.22 EER24117.1 - 1.8e-21 76.7 0.0 3.8e-21 75.7 0.0 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.23 EER24118.1 - 8.2e-67 225.3 0.0 9.8e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease DUF5529 PF17669.1 EER24118.1 - 8 6.5 13.2 7.1 6.6 11.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5529) zf-RING_2 PF13639.6 EER24119.1 - 3.6e-05 24.0 12.3 0.0019 18.5 5.6 2.9 2 1 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 EER24119.1 - 3.9e-05 23.6 11.6 4.1e-05 23.5 3.5 3.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EER24119.1 - 4.4e-05 23.2 9.7 6.5e-05 22.7 2.9 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-NOSIP PF15906.5 EER24119.1 - 0.00046 20.3 0.0 0.00093 19.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_5 PF14634.6 EER24119.1 - 0.00058 19.8 5.8 0.00058 19.8 5.8 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EER24119.1 - 0.00062 19.6 2.3 0.00062 19.6 2.3 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER24119.1 - 0.00074 19.3 15.7 0.0021 17.9 3.4 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EER24119.1 - 0.0016 18.5 12.0 0.012 15.7 4.3 3.3 2 2 1 3 3 3 1 FYVE zinc finger zf-C3HC4_5 PF17121.5 EER24119.1 - 0.013 15.3 2.5 0.049 13.5 2.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.14 EER24119.1 - 0.04 12.2 8.2 0.064 11.6 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-NADH-PPase PF09297.11 EER24119.1 - 0.13 11.9 1.3 0.82 9.4 0.2 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Zn_ribbon_17 PF17120.5 EER24119.1 - 0.55 9.9 9.2 3.8 7.2 0.2 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 EER24119.1 - 3 8.2 11.6 12 6.2 5.4 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 EER24119.1 - 3.8 7.7 11.7 0.9 9.7 3.8 3.2 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EER24119.1 - 6.9 6.6 19.0 0.34 10.8 7.2 3.7 3 2 1 4 4 4 0 Prokaryotic RING finger family 4 Hid1 PF12722.7 EER24119.1 - 9.9 4.1 8.2 13 3.7 8.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SET PF00856.28 EER24120.1 - 5e-09 36.8 1.7 1.4e-08 35.3 0.0 2.5 2 1 0 2 2 2 1 SET domain Vma12 PF11712.8 EER24120.1 - 0.24 11.4 0.2 0.49 10.5 0.2 1.5 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sec7 PF01369.20 EER24121.1 - 1.7e-31 109.3 0.0 2.7e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EER24121.1 - 2.4e-07 31.1 0.1 5.1e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EER24121.1 - 7.8e-07 29.6 0.1 2.1e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 PH domain Peptidase_M14 PF00246.24 EER24122.1 - 2.3e-74 250.8 0.0 3e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase WND PF07861.11 EER24122.1 - 0.014 14.9 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 WisP family N-Terminal Region NicO PF03824.16 EER24123.1 - 6e-48 163.6 11.2 3.2e-44 151.4 4.5 2.1 2 0 0 2 2 2 2 High-affinity nickel-transport protein Dynamin_N PF00350.23 EER24124.1 - 6.8e-06 26.2 0.0 2.8e-05 24.3 0.0 2.1 2 1 0 2 2 2 1 Dynamin family DNA_pol_B_thumb PF14791.6 EER24125.1 - 2.6e-22 78.7 0.4 7.5e-22 77.3 0.4 1.8 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EER24125.1 - 2.6e-18 65.6 0.4 5.1e-18 64.6 0.4 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EER24125.1 - 1e-14 54.7 0.7 6.7e-14 52.1 0.7 2.1 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 EER24125.1 - 1.3e-08 35.1 0.0 3.2e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain PhoLip_ATPase_C PF16212.5 EER24126.1 - 7.6e-83 278.1 20.7 7.6e-83 278.1 20.7 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EER24126.1 - 8.8e-27 92.6 9.9 2.9e-26 90.9 9.9 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EER24126.1 - 2.4e-11 44.3 0.9 9.8e-07 29.3 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EER24126.1 - 3.9e-11 42.9 0.0 1.3e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EER24126.1 - 1.3e-05 24.8 0.0 3.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EER24126.1 - 0.0037 17.0 0.4 0.023 14.4 0.1 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.21 EER24127.1 - 9.1e-21 74.7 0.1 1.8e-20 73.8 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EER24127.1 - 0.0002 21.3 0.1 0.00041 20.3 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Ribosomal_S5_C PF03719.15 EER24127.1 - 0.019 14.4 0.1 0.035 13.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain TBP PF00352.21 EER24127.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) Cwf_Cwc_15 PF04889.12 EER24128.1 - 6e-74 248.9 17.1 7.4e-74 248.6 17.1 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF3752 PF12572.8 EER24128.1 - 0.21 12.1 12.9 0.32 11.5 12.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) PA26 PF04636.13 EER24128.1 - 0.67 8.8 3.4 0.72 8.7 3.4 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Menin PF05053.13 EER24128.1 - 1.9 6.8 7.7 2.4 6.4 7.7 1.1 1 0 0 1 1 1 0 Menin CDC45 PF02724.14 EER24128.1 - 4.5 5.4 16.5 5.4 5.2 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DHFR_1 PF00186.19 EER24130.1 - 4.7e-16 58.9 0.1 3.2e-09 36.7 0.0 4.0 3 1 0 3 3 3 3 Dihydrofolate reductase Voltage_CLC PF00654.20 EER24131.1 - 4.6e-88 295.8 27.6 5.9e-88 295.5 24.5 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel Lipase_GDSL_2 PF13472.6 EER24132.1 - 3.7e-27 95.9 0.0 8.7e-27 94.7 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EER24132.1 - 5e-20 72.3 0.0 6e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 EER24132.1 - 0.00042 20.5 0.0 0.014 15.6 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Isochorismatase PF00857.20 EER24134.1 - 2e-26 93.2 0.0 2.6e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Linocin_M18 PF04454.12 EER24134.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Encapsulating protein for peroxidase HK PF02110.15 EER24135.1 - 3e-72 243.0 1.2 5e-72 242.2 0.1 1.8 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EER24135.1 - 8.3e-58 194.7 1.8 1.2e-57 194.1 1.8 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Sm_multidrug_ex PF06695.11 EER24135.1 - 0.049 14.3 0.6 0.049 14.3 0.6 1.7 2 0 0 2 2 2 0 Putative small multi-drug export protein eIF-5_eIF-2B PF01873.17 EER24136.1 - 5.4e-38 129.5 0.0 1.1e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EER24136.1 - 3.4e-21 75.1 0.1 1.1e-20 73.6 0.1 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon CFEM PF05730.11 EER24138.1 - 5.5e-13 48.8 4.7 9e-13 48.1 4.7 1.3 1 0 0 1 1 1 1 CFEM domain DNA_ligase_A_M PF01068.21 EER24140.1 - 3e-59 200.1 0.3 3.6e-57 193.3 0.3 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EER24140.1 - 1.5e-45 155.7 0.0 2.9e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EER24140.1 - 2.5e-27 95.4 0.0 7.8e-27 93.8 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EER24140.1 - 2.6e-06 27.8 0.1 4.7e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 RNA ligase DUF3246 PF11596.8 EER24140.1 - 0.00043 19.8 8.7 0.00043 19.8 8.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3246) mRNA_cap_enzyme PF01331.19 EER24141.1 - 8e-51 172.6 0.3 1.3e-50 171.9 0.3 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EER24141.1 - 2.9e-35 121.1 0.1 5.8e-35 120.2 0.1 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EER24141.1 - 3.1e-08 33.5 0.2 8.4e-06 25.6 0.1 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EER24141.1 - 0.00028 21.2 0.1 0.0005 20.4 0.1 1.5 1 0 0 1 1 1 1 RNA ligase SCA7 PF08313.12 EER24142.1 - 4.1e-31 106.7 0.9 4.1e-31 106.7 0.9 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF2151 PF10221.9 EER24142.1 - 0.085 11.4 5.0 0.11 11.1 5.0 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 EER24142.1 - 0.15 10.3 8.1 0.19 10.0 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4551 PF15087.6 EER24142.1 - 2.9 6.6 4.6 4.5 6.0 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 EER24142.1 - 4.8 5.9 5.5 7.4 5.2 5.5 1.3 1 0 0 1 1 1 0 Presenilin OrsD PF12013.8 EER24142.1 - 4.8 7.7 8.7 0.45 11.0 2.5 2.3 1 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D NPR3 PF03666.13 EER24142.1 - 8.5 5.0 9.4 12 4.5 9.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AIRC PF00731.20 EER24143.1 - 7e-60 200.9 1.1 1.2e-59 200.1 1.1 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EER24143.1 - 1.6e-52 177.6 0.2 4.6e-52 176.0 0.0 1.9 3 0 0 3 3 3 1 ATP-grasp domain PurK_C PF17769.1 EER24143.1 - 3.9e-18 64.9 0.0 9e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EER24143.1 - 1.6e-06 27.8 0.2 4.4e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 EER24143.1 - 1.2e-05 24.9 0.0 8.5e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 EER24143.1 - 0.0013 18.4 0.3 0.013 15.1 0.1 2.6 3 0 0 3 3 3 1 Propionate catabolism activator 2-Hacid_dh_C PF02826.19 EER24143.1 - 0.0092 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EER24143.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ketoacyl-synt PF00109.26 EER24144.1 - 1.2e-46 159.4 1.7 9.6e-46 156.4 0.3 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EER24144.1 - 1.2e-34 118.9 0.3 9.4e-34 116.0 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EER24144.1 - 2.3e-05 23.9 0.1 8.9e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EER24144.1 - 0.0065 16.1 1.2 0.46 10.1 0.1 3.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain Arginase PF00491.21 EER24145.1 - 3.2e-92 309.0 0.0 3.7e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EER24145.1 - 0.044 14.0 0.0 0.068 13.4 0.0 1.2 1 0 0 1 1 1 0 UPF0489 domain Ras PF00071.22 EER24146.1 - 1.2e-52 177.8 0.0 1.4e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER24146.1 - 6.5e-19 68.3 0.0 8.9e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER24146.1 - 5e-06 26.1 0.0 6.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family p450 PF00067.22 EER24148.1 - 1.1e-32 113.4 0.0 1.4e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EER24149.1 - 6.7e-24 84.5 40.1 2.1e-22 79.5 40.1 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER24149.1 - 0.0017 17.3 37.8 0.014 14.3 15.0 3.4 4 0 0 4 4 4 2 Sugar (and other) transporter Pox_A14 PF05767.12 EER24149.1 - 0.021 15.0 1.7 0.052 13.7 0.7 2.3 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF5360 PF17314.2 EER24149.1 - 0.045 13.8 0.1 0.045 13.8 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5360) DUF1349 PF07081.11 EER24150.1 - 3.4e-32 111.6 0.0 4e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) ABC_membrane PF00664.23 EER24151.1 - 8.4e-106 353.6 22.0 3.1e-59 200.9 3.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EER24151.1 - 2.3e-67 225.7 0.1 3.3e-33 115.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EER24151.1 - 5.6e-12 45.6 2.8 0.00048 19.6 0.2 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EER24151.1 - 7.6e-07 28.8 0.5 0.0024 17.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EER24151.1 - 1.9e-06 27.9 0.1 0.061 13.2 0.0 3.0 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 EER24151.1 - 2.2e-06 28.0 0.4 0.13 12.5 0.1 3.5 2 2 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 EER24151.1 - 9.7e-06 24.6 0.3 0.023 13.5 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 EER24151.1 - 2e-05 24.5 0.4 0.59 9.9 0.1 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EER24151.1 - 3.5e-05 23.2 0.0 0.017 14.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 EER24151.1 - 7.5e-05 22.7 0.1 0.1 12.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EER24151.1 - 8.9e-05 22.4 0.1 0.2 11.3 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_16 PF13191.6 EER24151.1 - 0.0001 22.8 5.0 0.21 12.0 0.3 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 EER24151.1 - 0.00017 21.3 0.8 0.75 9.5 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EER24151.1 - 0.00088 19.8 0.1 0.92 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EER24151.1 - 0.0013 19.2 0.1 2.9 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain G-alpha PF00503.20 EER24151.1 - 0.0024 17.1 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_28 PF13521.6 EER24151.1 - 0.0033 17.7 0.6 1.1 9.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EER24151.1 - 0.0033 17.8 0.9 4 7.9 0.3 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EER24151.1 - 0.0056 16.2 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region SbcCD_C PF13558.6 EER24151.1 - 0.0085 16.3 7.2 1.4 9.2 0.9 4.2 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 EER24151.1 - 0.0091 15.6 0.0 4.9 6.7 0.0 2.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.6 EER24151.1 - 0.011 15.8 0.0 5.9 6.9 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 EER24151.1 - 0.011 15.3 1.2 1.8 8.1 0.1 3.1 4 0 0 4 4 4 0 AAA domain ATP-synt_ab PF00006.25 EER24151.1 - 0.022 14.4 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.6 EER24151.1 - 0.024 14.8 0.0 10 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EER24151.1 - 0.034 13.9 0.0 3.7 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EER24151.1 - 0.048 13.4 0.2 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 EER24151.1 - 0.055 13.5 0.3 1.8 8.6 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain APS_kinase PF01583.20 EER24151.1 - 0.062 13.2 0.2 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase Rad17 PF03215.15 EER24151.1 - 0.094 12.6 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 EER24151.1 - 0.16 11.2 0.1 5 6.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain CAP59_mtransfer PF11735.8 EER24152.1 - 9e-72 241.6 0.0 1.2e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 GST_C PF00043.25 EER24155.1 - 5.6e-15 55.3 0.4 1.1e-14 54.4 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EER24155.1 - 9e-14 51.6 0.0 2.3e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EER24155.1 - 5.8e-12 45.8 0.0 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EER24155.1 - 9e-12 45.1 0.1 1.4e-11 44.5 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EER24155.1 - 2.6e-09 37.3 0.0 5.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EER24155.1 - 4.2e-05 23.5 0.1 0.00011 22.2 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EER24155.1 - 0.014 15.7 0.0 0.029 14.7 0.0 1.6 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EER24155.1 - 0.058 14.1 0.0 0.19 12.5 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EER24155.1 - 0.063 13.1 0.2 0.15 11.9 0.2 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Iwr1 PF08574.10 EER24156.1 - 3.1e-18 66.6 14.4 3.1e-18 66.6 14.4 2.8 3 0 0 3 3 3 1 Transcription factor Iwr1 RRM_1 PF00076.22 EER24157.1 - 1.3e-38 130.6 0.0 1.5e-11 43.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER24157.1 - 8.7e-13 47.9 0.0 0.005 16.7 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 EER24157.1 - 4.1e-07 29.6 4.0 4.1e-07 29.6 4.0 2.7 2 1 0 2 2 2 1 Putative RRM domain DUF4523 PF15023.6 EER24157.1 - 4.7e-05 23.3 0.0 0.43 10.4 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_7 PF16367.5 EER24157.1 - 0.00039 20.5 0.0 0.67 10.1 0.0 3.6 4 0 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 EER24157.1 - 0.0011 18.9 0.0 1.1 9.3 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif RRM_Rrp7 PF17799.1 EER24157.1 - 0.0093 15.8 0.1 1.4 8.7 0.0 3.7 3 1 1 4 4 4 1 Rrp7 RRM-like N-terminal domain YL1 PF05764.13 EER24158.1 - 3.1e-67 227.2 35.4 3.1e-67 227.2 35.4 2.3 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 EER24158.1 - 4.2e-14 52.0 0.4 6.9e-14 51.3 0.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain tRNA-synt_2 PF00152.20 EER24159.1 - 3.1e-88 295.9 0.0 4.1e-88 295.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EER24159.1 - 2.2e-08 33.9 0.0 4.1e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PUF PF00806.19 EER24160.1 - 3.3e-27 92.6 0.0 2e-05 24.0 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EER24160.1 - 5.3e-11 42.2 0.0 1.4e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 EER24160.1 - 0.26 10.9 7.0 0.63 9.6 7.0 1.6 1 0 0 1 1 1 0 Spt20 family MT-A70 PF05063.14 EER24161.1 - 7.3e-23 81.3 0.0 1.1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Peptidase_C12 PF01088.21 EER24162.1 - 1.1e-55 188.7 0.0 1.2e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DcpS PF05652.12 EER24163.1 - 1.1e-33 116.1 0.0 1.8e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EER24163.1 - 2.6e-30 105.3 0.1 3.8e-30 104.7 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Alk_phosphatase PF00245.20 EER24164.1 - 5.5e-71 239.7 0.8 3.5e-70 237.0 0.8 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EER24164.1 - 3e-07 30.1 3.3 1.9e-06 27.5 3.3 2.4 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EER24164.1 - 0.00026 20.7 0.1 0.00044 19.9 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EER24164.1 - 0.0022 16.7 0.2 0.0032 16.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) HHH_3 PF12836.7 EER24164.1 - 0.025 14.8 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Metalloenzyme PF01676.18 EER24164.1 - 0.032 13.6 0.6 0.082 12.3 0.6 1.6 1 0 0 1 1 1 0 Metalloenzyme superfamily RNase_H2_suC PF08615.11 EER24165.1 - 2.6e-30 105.4 0.0 3.5e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CENP-B_dimeris PF09026.10 EER24165.1 - 0.18 12.2 5.0 0.29 11.6 5.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNase_T PF00929.24 EER24166.1 - 6.5e-20 72.3 0.0 2e-19 70.7 0.0 1.8 1 1 0 1 1 1 1 Exonuclease PRKG1_interact PF15898.5 EER24166.1 - 2.6 9.0 8.5 0.72 10.8 4.8 1.9 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Nop53 PF07767.11 EER24167.1 - 7e-107 358.3 33.1 9e-107 357.9 33.1 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Asp-B-Hydro_N PF05279.11 EER24167.1 - 0.14 12.2 22.4 0.27 11.2 22.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Myb_Cef PF11831.8 EER24168.1 - 5.1e-52 176.8 7.6 5.1e-52 176.8 7.6 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EER24168.1 - 2.9e-22 78.6 4.6 2.1e-10 40.6 0.7 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER24168.1 - 2.5e-19 69.3 4.4 2.7e-12 46.7 1.2 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EER24168.1 - 0.011 15.8 0.8 0.99 9.5 0.0 3.5 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MOZ_SAS PF01853.18 EER24169.1 - 2.7e-79 265.0 0.0 3.7e-79 264.6 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EER24169.1 - 8e-23 79.8 0.3 1.6e-22 78.9 0.3 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EER24169.1 - 7e-22 77.1 0.0 1.4e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EER24169.1 - 0.0013 19.1 0.0 0.0027 18.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER24169.1 - 0.0097 16.1 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Agenet PF05641.12 EER24169.1 - 0.069 13.6 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Agenet domain DUF5633 PF18656.1 EER24169.1 - 0.97 9.4 3.7 4.2 7.3 3.7 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5633) F1F0-ATPsyn_F PF10791.9 EER24171.1 - 1.3e-37 128.1 0.2 1.6e-37 127.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EER24171.1 - 0.00064 20.1 0.1 0.0016 18.8 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.12 EER24172.1 - 1.6e-36 124.4 1.7 2.3e-36 123.9 1.7 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region HEAT_2 PF13646.6 EER24173.1 - 9.2e-29 99.7 5.8 5.5e-14 52.3 1.3 4.1 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EER24173.1 - 2.2e-19 68.1 0.9 0.022 15.4 0.5 7.3 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EER24173.1 - 1.4e-07 31.2 4.6 1.4 9.3 0.0 7.1 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EER24173.1 - 7.9e-05 23.1 4.4 0.049 14.1 0.0 4.8 4 1 1 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.7 EER24173.1 - 0.033 14.5 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion TFIIS_C PF01096.18 EER24174.1 - 6.2e-15 54.8 1.8 6.2e-15 54.8 1.8 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EER24174.1 - 9.3e-08 31.8 8.0 1.7e-06 27.8 1.1 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Nudix_N_2 PF14803.6 EER24174.1 - 0.00038 20.3 1.4 0.038 13.9 0.4 2.6 2 0 0 2 2 2 1 Nudix N-terminal RecR PF02132.15 EER24174.1 - 0.0021 17.6 1.0 0.0021 17.6 1.0 2.2 2 0 0 2 2 2 1 RecR protein DZR PF12773.7 EER24174.1 - 0.019 15.0 6.5 0.33 11.0 3.5 2.6 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_1 PF14446.6 EER24174.1 - 0.11 12.5 4.3 0.98 9.4 1.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_7 PF02591.15 EER24174.1 - 0.15 12.3 5.7 0.73 10.1 0.1 3.2 2 1 1 3 3 3 0 C4-type zinc ribbon domain tRNA-synt_1f PF01921.18 EER24174.1 - 0.16 10.9 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Ribosomal_S27e PF01667.17 EER24174.1 - 0.25 11.1 3.6 2.9 7.7 0.0 3.1 2 1 1 3 3 3 0 Ribosomal protein S27 zf-ribbon_3 PF13248.6 EER24174.1 - 0.3 10.5 7.8 14 5.2 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain PHD PF00628.29 EER24174.1 - 0.36 10.8 5.2 3.8 7.5 2.1 2.8 2 1 1 3 3 3 0 PHD-finger RNHCP PF12647.7 EER24174.1 - 0.44 10.5 4.6 2.6 8.1 2.9 2.7 1 1 1 2 2 2 0 RNHCP domain zinc_ribbon_2 PF13240.6 EER24174.1 - 0.48 10.2 9.6 15 5.5 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 EER24174.1 - 0.64 9.9 4.8 8.2 6.3 0.4 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 XPA_N PF01286.18 EER24174.1 - 3.2 7.9 0.1 3.2 7.9 0.1 3.3 4 0 0 4 4 4 0 XPA protein N-terminal Nipped-B_C PF12830.7 EER24175.1 - 2.4e-52 177.6 6.2 1e-48 165.8 1.5 3.3 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EER24175.1 - 6.8e-12 45.5 2.1 6.8e-12 45.5 2.1 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 EER24175.1 - 2.7e-07 30.1 2.9 0.016 14.4 0.0 3.9 3 0 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 EER24175.1 - 7.5e-06 26.1 2.6 0.085 12.9 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EER24175.1 - 4.2e-05 23.5 2.4 0.23 11.8 0.2 4.9 4 0 0 4 4 4 1 HEAT repeat FAM176 PF14851.6 EER24175.1 - 0.11 12.2 0.5 0.31 10.7 0.5 1.7 1 0 0 1 1 1 0 FAM176 family Pyr_redox_2 PF07992.14 EER24176.1 - 5.9e-40 137.3 0.0 7.9e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER24176.1 - 9.6e-11 42.1 0.0 4.1e-09 36.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EER24176.1 - 7.9e-07 28.2 0.1 3.3e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EER24176.1 - 3.3e-06 26.6 0.4 1.2e-05 24.9 0.4 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EER24176.1 - 6.6e-05 23.3 0.1 0.00019 21.8 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EER24176.1 - 8.7e-05 21.8 0.4 0.00023 20.5 0.4 1.7 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.6 EER24176.1 - 0.25 10.5 0.1 13 4.9 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.9 EER24177.1 - 1.1e-33 116.2 0.6 1.7e-33 115.6 0.6 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EER24177.1 - 1.4e-08 34.4 0.0 2.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 LisH PRK PF00485.18 EER24178.1 - 3.4e-56 190.1 0.0 4e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EER24178.1 - 4.1e-08 33.8 0.0 5.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EER24178.1 - 9.2e-06 25.1 0.0 1.5e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.17 EER24178.1 - 0.00029 21.0 0.2 0.00036 20.7 0.2 1.5 1 1 0 1 1 1 1 Helicase HerA, central domain Cytidylate_kin PF02224.18 EER24178.1 - 0.0011 18.7 0.1 0.15 11.8 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase CPT PF07931.12 EER24178.1 - 0.0023 17.8 0.2 0.0074 16.1 0.0 1.9 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 EER24178.1 - 0.0042 17.5 1.4 0.16 12.4 1.4 2.3 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 EER24178.1 - 0.0098 15.9 0.0 0.02 15.0 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EER24178.1 - 0.011 15.8 0.0 0.037 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EER24178.1 - 0.021 15.2 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EER24178.1 - 0.03 14.8 0.0 0.049 14.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter CoaE PF01121.20 EER24178.1 - 0.053 13.2 0.2 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase APS_kinase PF01583.20 EER24178.1 - 0.056 13.3 0.1 0.34 10.8 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase TrwB_AAD_bind PF10412.9 EER24178.1 - 0.11 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Cytidylate_kin2 PF13189.6 EER24178.1 - 0.12 12.5 0.1 16 5.6 0.1 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_24 PF13479.6 EER24178.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EER24178.1 - 0.16 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Tubulin PF00091.25 EER24178.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain NUC153 PF08159.12 EER24179.1 - 1e-14 54.0 12.0 4.5e-13 48.7 0.2 3.8 3 0 0 3 3 3 3 NUC153 domain DUF2431 PF10354.9 EER24179.1 - 0.068 13.4 0.1 0.13 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) ATP-synt_J PF04911.12 EER24179.1 - 0.18 11.4 0.7 1.8 8.2 0.2 2.5 1 1 1 2 2 2 0 ATP synthase j chain Npa1 PF11707.8 EER24180.1 - 7.2e-97 324.8 1.5 1.1e-96 324.2 0.0 2.1 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EER24180.1 - 4.7e-58 196.1 0.2 1.6e-57 194.3 0.2 2.0 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 HEAT_EZ PF13513.6 EER24180.1 - 0.009 16.5 0.0 4.7 7.8 0.0 3.7 3 0 0 3 3 3 1 HEAT-like repeat UNC45-central PF11701.8 EER24180.1 - 0.076 13.0 1.4 20 5.1 0.2 3.8 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central HA2 PF04408.23 EER24182.1 - 2.3e-25 89.0 0.2 8.7e-25 87.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EER24182.1 - 8e-20 71.0 0.0 1.6e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EER24182.1 - 9.4e-14 51.7 0.2 2.8e-13 50.2 0.0 1.9 2 0 0 2 2 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EER24182.1 - 5.1e-09 36.4 0.6 1.2e-08 35.2 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EER24182.1 - 9.8e-05 22.2 0.2 0.00025 20.8 0.2 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EER24182.1 - 0.00089 19.6 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EER24182.1 - 0.002 17.2 0.0 0.0048 16.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EER24182.1 - 0.0025 18.2 0.1 0.0049 17.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EER24182.1 - 0.0026 17.5 0.0 0.0075 16.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EER24182.1 - 0.044 13.0 0.0 0.083 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EER24182.1 - 0.079 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 EER24182.1 - 0.15 12.0 0.4 3.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Microtubule binding SUV3_C PF12513.8 EER24183.1 - 4.7e-18 64.9 0.2 2.7e-17 62.4 0.2 2.3 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EER24183.1 - 1.6e-10 41.3 0.0 3.3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EER24183.1 - 2.2e-08 33.8 0.0 4.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 RepA_C PF04796.12 EER24183.1 - 0.078 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Plasmid encoded RepA protein Spore_II_R PF09551.10 EER24183.1 - 0.25 11.8 1.8 0.68 10.4 0.1 2.2 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Sec1 PF00995.23 EER24184.1 - 3.3e-117 393.1 0.0 4.2e-117 392.8 0.0 1.1 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.23 EER24185.1 - 1e-06 28.5 0.7 1.5e-06 28.0 0.0 1.7 2 0 0 2 2 2 1 G-patch domain DUF1178 PF06676.11 EER24185.1 - 0.82 10.1 5.5 4 7.8 5.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) FAP PF07174.11 EER24185.1 - 4.7 6.6 18.4 0.02 14.4 5.6 2.1 1 1 1 2 2 2 0 Fibronectin-attachment protein (FAP) adh_short PF00106.25 EER24186.1 - 1.3e-12 47.6 0.0 5e-10 39.2 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EER24186.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EER24186.1 - 0.001 18.7 0.0 0.011 15.3 0.0 2.4 1 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EER24186.1 - 0.0021 17.6 0.3 0.021 14.3 0.3 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2654 PF10849.8 EER24186.1 - 0.08 13.1 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) Pyr_redox_3 PF13738.6 EER24186.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4217 PF13959.6 EER24186.1 - 0.15 12.3 0.2 0.43 10.8 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) TMP_2 PF06791.13 EER24186.1 - 0.21 11.3 1.5 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Prophage tail length tape measure protein GDP_Man_Dehyd PF16363.5 EER24187.1 - 8.6e-50 170.0 0.0 2.6e-49 168.4 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EER24187.1 - 2.9e-45 154.6 0.0 6.6e-45 153.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EER24187.1 - 7.4e-16 58.0 0.0 1.5e-15 57.0 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EER24187.1 - 7.5e-11 41.7 0.0 3.3e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EER24187.1 - 2.3e-09 36.8 0.0 3.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EER24187.1 - 3.3e-08 33.2 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER24187.1 - 7.3e-06 26.0 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EER24187.1 - 0.00018 20.8 0.0 0.00068 18.9 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein adh_short_C2 PF13561.6 EER24187.1 - 0.00058 19.5 0.0 0.00095 18.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EER24188.1 - 8.7e-26 90.9 0.0 1.1e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EER24188.1 - 3.5e-09 36.6 0.0 4.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EER24188.1 - 2.5e-07 30.4 0.1 1.7e-06 27.7 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EER24188.1 - 0.00012 22.4 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EER24188.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EER24188.1 - 0.015 14.3 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 EER24188.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EER24188.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EER24188.1 - 0.15 12.3 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain PAT1 PF09770.9 EER24189.1 - 0 1183.1 2.5 0 1182.9 2.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF5611 PF18446.1 EER24189.1 - 0.18 12.7 0.0 0.54 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5611) Arg_decarbox_C PF17944.1 EER24189.1 - 6.9 7.3 5.3 26 5.5 0.6 3.8 4 0 0 4 4 4 0 Arginine decarboxylase C-terminal helical extension Glyco_transf_15 PF01793.16 EER24190.1 - 7.3e-126 419.8 6.9 8.9e-126 419.5 6.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.25 EER24191.1 - 2.6e-31 107.6 0.9 3.6e-31 107.1 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UMP1 PF05348.11 EER24192.1 - 5.4e-40 136.3 0.0 7e-40 135.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.6 EER24193.1 - 5.1e-10 39.4 0.0 9.4e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EER24193.1 - 0.0044 17.6 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EER24193.1 - 0.086 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin family GHMP_kinases_N PF00288.26 EER24194.1 - 3.4e-15 56.0 0.6 9.2e-15 54.6 0.6 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EER24194.1 - 2.7e-08 34.1 0.0 5.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal SRP_SPB PF02978.19 EER24194.1 - 0.11 13.2 0.1 4.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Signal peptide binding domain THOC7 PF05615.13 EER24194.1 - 0.14 12.4 0.7 0.27 11.5 0.7 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 MCM PF00493.23 EER24195.1 - 5.3e-100 333.1 0.1 7.8e-100 332.6 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EER24195.1 - 8.6e-39 132.3 0.1 1.9e-38 131.1 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EER24195.1 - 2.6e-34 117.7 3.1 2.6e-34 117.7 3.1 2.1 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EER24195.1 - 3.4e-24 85.1 0.7 1.2e-23 83.4 0.1 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EER24195.1 - 6.6e-22 78.1 0.6 2.3e-21 76.3 0.6 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EER24195.1 - 4.2e-05 23.0 0.0 0.00019 20.9 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EER24195.1 - 0.0004 20.4 0.1 0.0057 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EER24195.1 - 0.0069 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EER24195.1 - 0.011 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GIDA_assoc PF13932.6 EER24195.1 - 0.24 11.6 3.8 0.27 11.4 2.3 1.9 2 0 0 2 2 2 0 GidA associated domain Helicase_C PF00271.31 EER24196.1 - 7.4e-08 32.7 0.0 1.5e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EER24196.1 - 0.0075 16.1 10.3 0.022 14.6 10.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER24196.1 - 0.019 15.0 4.4 0.019 15.0 4.4 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EER24196.1 - 0.048 13.5 9.6 0.092 12.6 9.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER24196.1 - 0.14 12.1 9.8 0.32 11.0 9.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EER24196.1 - 0.23 11.7 6.8 0.096 12.9 3.2 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EER24196.1 - 0.63 9.9 8.2 1.7 8.6 8.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EER24196.1 - 1 9.3 8.1 1.9 8.4 8.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EER24196.1 - 9.1 6.7 10.5 18 5.8 8.9 2.3 2 0 0 2 2 2 0 Ring finger domain DLIC PF05783.11 EER24197.1 - 0.16 10.7 6.7 0.29 9.9 6.7 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FNIP_N PF14636.6 EER24198.1 - 4.2e-30 105.8 0.4 4.2e-30 105.8 0.4 4.5 4 1 1 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 EER24198.1 - 0.051 13.6 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Ribosomal_L7Ae PF01248.26 EER24199.1 - 2e-25 88.4 0.0 2.9e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EER24199.1 - 0.00036 20.6 0.0 0.00049 20.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EER24199.1 - 0.0032 17.3 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain Fungal_trans PF04082.18 EER24200.1 - 2.5e-23 82.5 0.0 3.8e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER24200.1 - 5.8e-05 23.1 7.8 0.0001 22.3 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5488 PF17590.2 EER24200.1 - 0.054 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5488) Na_Ca_ex PF01699.24 EER24202.1 - 6.7e-43 146.2 39.1 2.3e-24 86.1 15.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein IML1 PF12257.8 EER24203.1 - 1.7e-108 362.1 0.0 2.3e-108 361.6 0.0 1.2 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EER24203.1 - 7e-29 99.7 1.2 1.4e-28 98.7 1.2 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PPR_2 PF13041.6 EER24204.1 - 1.4e-40 137.3 16.0 3.9e-09 36.6 0.0 12.7 9 4 5 14 14 14 7 PPR repeat family PPR_3 PF13812.6 EER24204.1 - 1.4e-35 121.1 0.6 2.3e-05 24.3 0.0 11.5 8 3 2 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.20 EER24204.1 - 6.5e-23 79.3 25.9 0.0011 19.1 0.0 14.0 16 0 0 16 16 16 6 PPR repeat PPR_long PF17177.4 EER24204.1 - 1.1e-20 74.0 12.9 3.4e-08 33.1 0.1 6.5 4 2 0 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EER24204.1 - 9e-20 70.1 3.5 2.4e-06 27.1 0.0 9.8 11 0 0 11 11 11 4 PPR repeat TPR_14 PF13428.6 EER24204.1 - 4.5e-05 23.9 2.2 37 5.5 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat RPM2 PF08579.11 EER24204.1 - 0.0001 22.7 0.1 0.0066 16.8 0.0 3.6 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) RPN7 PF10602.9 EER24204.1 - 0.00096 18.9 0.0 0.6 9.8 0.0 3.5 3 0 0 3 3 3 1 26S proteasome subunit RPN7 PNP_phzG_C PF10590.9 EER24205.1 - 6.4e-20 71.0 6.2 1.8e-19 69.5 3.7 2.5 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EER24205.1 - 3.9e-10 39.8 0.3 0.00056 20.1 0.0 3.1 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase EamA PF00892.20 EER24206.1 - 0.00046 20.4 15.1 0.0034 17.6 15.1 1.9 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EER24206.1 - 0.0033 17.4 4.2 0.0046 17.0 4.2 1.3 1 0 0 1 1 1 1 Putative transmembrane family 234 DUF543 PF04418.12 EER24206.1 - 0.017 15.1 0.3 0.042 13.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Ca_hom_mod PF14798.6 EER24206.1 - 0.14 11.3 1.7 0.23 10.5 1.7 1.3 1 0 0 1 1 1 0 Calcium homeostasis modulator Voltage_CLC PF00654.20 EER24207.1 - 8.1e-87 291.7 31.5 8.1e-87 291.7 31.5 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EER24207.1 - 7.3e-10 39.1 0.1 0.00054 20.4 0.0 2.7 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.23 EER24208.1 - 1.1e-14 54.5 0.3 1.1e-14 54.5 0.3 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DSPn PF14671.6 EER24208.1 - 0.031 14.7 0.1 0.047 14.1 0.1 1.2 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half TAFII28 PF04719.14 EER24208.1 - 0.056 13.5 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Rieske PF00355.26 EER24209.1 - 3.7e-11 42.8 0.0 6.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EER24209.1 - 8.6e-10 39.0 1.9 2e-09 37.8 1.9 1.6 1 1 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region She9_MDM33 PF05546.11 EER24210.1 - 4.6e-88 294.2 7.8 6.8e-88 293.7 7.8 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PAS_9 PF13426.7 EER24210.1 - 0.077 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain PsbH PF00737.20 EER24210.1 - 0.38 10.5 4.8 0.12 12.1 0.8 1.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein GvpL_GvpF PF06386.11 EER24210.1 - 0.46 10.4 5.5 0.85 9.5 5.5 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Uso1_p115_C PF04871.13 EER24210.1 - 0.85 10.0 10.7 11 6.4 5.9 3.2 2 2 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pmp3 PF01679.17 EER24211.1 - 8.5e-19 67.5 9.4 1.1e-18 67.1 9.4 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SH3_9 PF14604.6 EER24212.1 - 2.8e-06 27.1 0.2 5.8e-06 26.1 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EER24212.1 - 0.00016 21.2 0.1 0.00033 20.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain MFS_1 PF07690.16 EER24213.1 - 2.5e-17 62.8 63.3 8.2e-17 61.1 58.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER24213.1 - 5.2e-07 28.5 27.5 8.6e-07 27.7 27.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.12 EER24213.1 - 0.14 12.3 4.0 0.42 10.8 2.0 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 CFEM PF05730.11 EER24214.1 - 2.5e-10 40.3 4.4 3.7e-10 39.7 4.4 1.3 1 0 0 1 1 1 1 CFEM domain SprA_N PF14349.6 EER24216.1 - 0.15 10.8 0.1 5.2 5.8 0.0 2.0 1 1 1 2 2 2 0 Motility related/secretion protein RSN1_7TM PF02714.15 EER24217.1 - 8e-91 304.1 26.7 6.9e-89 297.8 20.5 2.8 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EER24217.1 - 1.5e-44 151.5 0.6 1.5e-44 151.5 0.6 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EER24217.1 - 1.2e-34 120.0 0.1 1.9e-34 119.4 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EER24217.1 - 1.1e-31 108.9 0.1 3.8e-31 107.1 0.1 2.0 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter DUP PF00674.18 EER24219.1 - 0.014 15.5 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 DUP family Pyridox_oxase_2 PF12766.7 EER24220.1 - 5.2e-23 81.6 0.0 1.6e-22 79.9 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF818 PF05677.12 EER24220.1 - 0.23 10.4 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) LRR_9 PF14580.6 EER24221.1 - 2.2e-61 206.4 0.1 2.2e-61 206.4 0.1 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EER24221.1 - 1.4e-07 31.1 1.3 1.4e-07 31.1 1.3 2.3 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EER24221.1 - 7.4e-07 29.4 8.3 0.00012 22.3 0.3 3.4 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) HTH_38 PF13936.6 EER24221.1 - 0.0028 17.4 0.4 0.02 14.7 0.7 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain DUF4349 PF14257.6 EER24221.1 - 0.016 14.7 1.8 0.027 13.9 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) HTH_32 PF13565.6 EER24221.1 - 0.12 13.1 1.4 0.3 11.7 1.1 1.8 1 1 1 2 2 2 0 Homeodomain-like domain LRR_6 PF13516.6 EER24221.1 - 8.9 6.7 7.0 27 5.2 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat GDA1_CD39 PF01150.17 EER24222.1 - 1.2e-106 357.0 0.0 1.6e-106 356.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Velvet PF11754.8 EER24223.1 - 7.7e-08 32.6 0.0 2.2e-07 31.1 0.0 1.6 1 1 1 2 2 2 1 Velvet factor Acyltransferase PF01553.21 EER24224.1 - 8.8e-18 64.2 0.0 1.8e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Pantoate_ligase PF02569.15 EER24225.1 - 2.9e-93 311.9 0.0 3.4e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.29 EER24226.1 - 3.2e-42 144.3 0.0 5.1e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER24226.1 - 2.2e-19 69.9 0.0 1e-18 67.7 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EER24226.1 - 1.1e-18 67.2 0.1 2.3e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EER24226.1 - 2.6e-05 24.3 0.0 6.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EER24226.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 EER24227.1 - 9.7e-12 45.2 9.2 0.011 16.6 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER24227.1 - 0.00044 20.5 1.2 10 6.5 0.0 4.7 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain AAR2 PF05282.11 EER24227.1 - 0.037 13.4 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 AAR2 protein Zn_clus PF00172.18 EER24228.1 - 3.8e-05 23.7 11.1 3.8e-05 23.7 11.1 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EER24229.1 - 5.1e-43 147.3 45.7 5.8e-41 140.6 45.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER24229.1 - 5.2e-09 35.5 19.7 5.2e-09 35.5 19.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EER24229.1 - 1.3e-05 23.8 18.6 1.8e-05 23.4 18.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MHYT PF03707.16 EER24229.1 - 0.17 12.1 11.0 4.3 7.6 0.1 4.2 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat GATase PF00117.28 EER24230.1 - 1.8e-13 50.7 0.0 2.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EER24230.1 - 0.019 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EER24230.1 - 0.17 11.6 0.1 1.8 8.2 0.1 2.3 2 1 0 2 2 2 0 Peptidase C26 DUF775 PF05603.12 EER24231.1 - 1.1e-65 220.9 0.0 1.2e-65 220.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.28 EER24232.1 - 8.6e-12 45.2 0.0 1.5e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 EER24232.1 - 3.4e-10 39.9 0.0 4.8e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) RNA_pol_Rpb8 PF03870.15 EER24233.1 - 1.7e-45 154.6 0.0 1.9e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.11 EER24234.1 - 1.2e-115 386.6 0.0 1.4e-115 386.4 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EER24235.1 - 3.6e-14 52.6 0.0 1.1e-13 51.1 0.0 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain UPF0086 PF01868.16 EER24236.1 - 2.7e-31 107.3 0.0 4.2e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Pkinase_Tyr PF07714.17 EER24236.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase 2OG-FeII_Oxy PF03171.20 EER24237.1 - 1.3e-14 54.5 0.0 2.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EER24237.1 - 2.3e-13 50.9 0.0 4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Copper-bind PF00127.20 EER24239.1 - 0.0065 16.9 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EER24239.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain FYVE_2 PF02318.16 EER24240.1 - 0.23 11.7 33.2 1.9 8.7 6.3 3.9 3 1 0 4 4 4 0 FYVE-type zinc finger Zn_ribbon_17 PF17120.5 EER24240.1 - 0.32 10.7 31.7 0.11 12.2 7.6 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type DUF3725 PF12523.8 EER24240.1 - 0.36 11.2 2.5 1.5 9.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) Cofilin_ADF PF00241.20 EER24241.1 - 1.2e-16 60.5 0.0 1.4e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 EER24242.1 - 3.4e-35 120.8 0.0 5.5e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain RNase_P_p30 PF01876.16 EER24242.1 - 0.2 11.1 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit p30 Ras PF00071.22 EER24243.1 - 8.7e-60 201.0 0.2 1e-59 200.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER24243.1 - 2.2e-20 73.1 0.0 3.6e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER24243.1 - 2.3e-08 33.7 0.0 2.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EER24243.1 - 9.6e-07 28.5 0.1 1.1e-05 25.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EER24243.1 - 0.00014 21.8 1.0 0.54 10.1 0.0 2.4 1 1 1 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EER24243.1 - 0.0019 18.2 0.0 0.0031 17.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EER24243.1 - 0.003 17.6 0.0 0.0067 16.4 0.0 1.6 1 1 0 1 1 1 1 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EER24243.1 - 0.005 16.4 0.1 0.0099 15.4 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ParA PF10609.9 EER24243.1 - 0.12 11.9 0.1 0.94 8.9 0.0 2.0 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase IstB_IS21 PF01695.17 EER24243.1 - 0.17 11.6 1.0 2.6 7.8 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 EER24243.1 - 0.38 10.5 2.3 2.4 7.9 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein adh_short PF00106.25 EER24244.1 - 1.4e-53 181.3 0.0 1.8e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER24244.1 - 3.1e-37 128.4 0.0 3.7e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER24244.1 - 2.1e-12 47.3 0.0 3.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EER24244.1 - 0.021 15.1 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EER24244.1 - 0.032 13.4 0.0 0.098 11.8 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AAA_22 PF13401.6 EER24244.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain GATA PF00320.27 EER24246.1 - 5.2e-28 96.3 18.3 2.2e-14 52.8 5.1 2.4 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EER24246.1 - 2.2e-06 27.1 2.7 0.00095 18.6 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 EER24246.1 - 0.012 15.6 10.7 4.9 7.3 0.6 3.2 1 1 1 2 2 2 0 Double zinc ribbon ArfGap PF01412.18 EER24246.1 - 0.014 15.5 2.5 0.69 10.0 0.1 2.4 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Auto_anti-p27 PF06677.12 EER24246.1 - 0.019 15.1 6.6 0.6 10.3 0.4 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 EER24246.1 - 0.03 14.4 8.2 0.11 12.6 0.3 2.9 3 0 0 3 3 3 0 Zinc ribbon domain TDP43_N PF18694.1 EER24246.1 - 0.2 11.5 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain CCDC-167 PF15188.6 EER24246.1 - 0.96 9.8 3.1 1.8 9.0 3.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 COPI_assoc PF08507.10 EER24247.1 - 2.1e-27 95.7 2.7 2.2e-27 95.6 2.7 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2583 PF10762.9 EER24247.1 - 0.06 13.8 1.2 4.6 7.7 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) MFS_MOT1 PF16983.5 EER24247.1 - 0.58 10.6 5.0 1.7 9.1 0.9 2.1 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily Sugar_tr PF00083.24 EER24249.1 - 8.1e-103 344.7 19.9 1e-102 344.4 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER24249.1 - 1.7e-14 53.6 30.0 6.2e-13 48.4 2.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.8 EER24249.1 - 0.69 9.7 2.8 1.6 8.5 2.8 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 zf-CCHC PF00098.23 EER24250.1 - 6.9e-13 48.0 16.1 3.1e-07 30.2 1.4 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.6 EER24250.1 - 0.0028 17.5 6.8 0.35 10.8 0.2 2.6 2 0 0 2 2 2 2 Zinc knuckle zf-C2H2_10 PF16588.5 EER24250.1 - 0.014 15.1 10.5 0.031 14.0 1.7 2.6 3 0 0 3 3 3 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 EER24250.1 - 0.028 14.2 0.5 0.028 14.2 0.5 3.0 2 1 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 EER24250.1 - 0.064 13.2 0.6 0.064 13.2 0.6 3.2 1 1 2 3 3 3 0 Zinc knuckle zinc_ribbon_12 PF11331.8 EER24250.1 - 0.098 12.5 2.1 0.18 11.7 2.1 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-CCHC_4 PF14392.6 EER24250.1 - 0.14 11.9 11.5 0.16 11.7 1.2 3.0 3 0 0 3 3 3 0 Zinc knuckle PHD PF00628.29 EER24250.1 - 0.16 11.9 8.7 1.4 8.9 1.6 2.4 1 1 1 2 2 2 0 PHD-finger FAD_binding_3 PF01494.19 EER24251.1 - 6.5e-13 48.6 0.0 2.8e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EER24251.1 - 0.0058 16.6 0.0 0.83 9.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EER24251.1 - 0.021 14.1 0.0 0.59 9.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EER24251.1 - 0.021 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EER24251.1 - 0.024 14.8 0.0 0.062 13.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EER24251.1 - 0.11 11.5 0.0 0.3 10.1 0.0 1.7 1 1 0 1 1 1 0 Squalene epoxidase ECH_1 PF00378.20 EER24252.1 - 5.7e-46 156.9 0.0 7.3e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER24252.1 - 3e-23 82.9 0.0 2.4e-20 73.3 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EER24252.1 - 0.14 12.1 0.0 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Acyl-CoA_dh_1 PF00441.24 EER24253.1 - 2.1e-29 102.7 0.1 2.8e-29 102.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EER24253.1 - 4.2e-23 81.4 0.0 7e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EER24253.1 - 3.4e-22 79.2 0.2 3.7e-21 75.9 0.2 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EER24253.1 - 0.0091 16.3 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpcH_HpaI PF03328.14 EER24254.1 - 7.7e-46 156.0 0.1 1.6e-45 154.9 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EER24254.1 - 9.7e-14 51.3 0.1 7.9e-11 41.7 0.1 2.1 1 1 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold SBE2 PF17076.5 EER24254.1 - 0.08 11.2 0.2 0.099 10.8 0.2 1.1 1 0 0 1 1 1 0 SBE2, cell-wall formation DUF1771 PF08590.10 EER24255.1 - 2.5e-12 46.9 7.9 5e-12 46.0 7.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EER24255.1 - 1.2e-07 31.9 0.0 3.8e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 EER24255.1 - 1.8e-07 30.9 0.6 0.0046 16.9 0.1 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EER24255.1 - 2e-07 30.8 7.3 0.00012 22.0 0.4 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 EER24255.1 - 6.2e-05 23.2 2.1 0.092 13.0 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EER24255.1 - 8.5e-05 22.9 4.1 0.16 12.5 0.3 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EER24255.1 - 9.1e-05 22.2 10.5 0.0036 17.1 0.6 3.2 2 1 0 2 2 2 2 CCCH-type zinc finger CUE PF02845.16 EER24255.1 - 0.084 12.6 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 CUE domain CNP_C_terminal PF17839.1 EER24255.1 - 0.099 13.4 0.0 0.2 12.4 0.0 1.5 1 0 0 1 1 1 0 C-terminal domain of cyclic nucleotide phosphodiesterase Torus PF16131.5 EER24255.1 - 0.22 12.2 2.0 6.5 7.5 0.4 2.5 1 1 1 2 2 2 0 Torus domain SNARE_assoc PF09335.11 EER24256.1 - 4e-12 46.7 5.4 4e-12 46.7 5.4 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF872 PF05915.12 EER24256.1 - 0.013 15.7 2.0 0.092 12.9 0.6 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SHR3_chaperone PF08229.11 EER24256.1 - 0.12 11.3 0.8 2.9 6.8 0.2 2.2 2 0 0 2 2 2 0 ER membrane protein SH3 DUF3552 PF12072.8 EER24256.1 - 0.22 10.9 0.2 0.34 10.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Yip1 PF04893.17 EER24256.1 - 0.4 10.4 19.5 1.7 8.3 0.5 2.2 2 0 0 2 2 2 0 Yip1 domain Romo1 PF10247.9 EER24256.1 - 0.67 10.4 4.3 40 4.7 0.0 2.8 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Amino_oxidase PF01593.24 EER24257.1 - 9.3e-87 292.2 0.0 2.5e-75 254.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 EER24257.1 - 5.3e-15 55.5 1.2 7.9e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain NAD_binding_8 PF13450.6 EER24257.1 - 1.1e-07 32.0 0.0 2.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER24257.1 - 0.00086 19.0 0.1 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EER24257.1 - 0.0014 18.6 0.3 0.89 9.5 0.1 3.2 2 1 0 2 2 2 2 FAD-NAD(P)-binding HMG_box PF00505.19 EER24257.1 - 0.0016 18.9 2.0 0.0051 17.2 2.0 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box Pyr_redox_2 PF07992.14 EER24257.1 - 0.0057 15.9 0.1 0.041 13.1 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HMG_box_2 PF09011.10 EER24257.1 - 0.0082 16.7 0.7 0.022 15.3 0.7 1.7 1 0 0 1 1 1 1 HMG-box domain HI0933_like PF03486.14 EER24257.1 - 0.32 9.7 0.4 0.76 8.4 0.2 1.7 2 0 0 2 2 2 0 HI0933-like protein Vps5 PF09325.10 EER24257.1 - 1.5 8.3 4.2 2.7 7.5 4.2 1.3 1 0 0 1 1 1 0 Vps5 C terminal like Pyr_redox_2 PF07992.14 EER24258.1 - 2.9e-50 171.2 0.1 3.5e-50 170.9 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER24258.1 - 2.2e-18 66.6 0.2 1.8e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER24258.1 - 3.2e-16 59.7 0.3 1.5e-13 51.1 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER24258.1 - 3.4e-05 24.0 0.1 0.03 14.6 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EER24258.1 - 9.3e-05 21.8 0.2 0.00031 20.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EER24258.1 - 0.00049 20.5 0.1 0.039 14.4 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.19 EER24258.1 - 0.0061 15.8 0.1 1.9 7.6 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 EER24258.1 - 0.0073 15.5 0.0 0.26 10.4 0.0 2.9 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EER24258.1 - 0.019 14.1 4.4 0.22 10.5 0.2 2.7 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.22 EER24258.1 - 0.11 11.5 7.5 1.3 8.0 0.1 3.6 2 1 1 3 3 3 0 Glucose inhibited division protein A Shikimate_DH PF01488.20 EER24258.1 - 0.14 12.2 0.2 10 6.2 0.0 2.7 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase LEA_1 PF03760.15 EER24259.1 - 0.059 14.0 1.9 0.11 13.1 1.9 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Peptidase_S8 PF00082.22 EER24260.1 - 4e-36 124.8 0.8 9.1e-36 123.6 0.8 1.6 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EER24260.1 - 3.9e-28 97.3 0.7 8.4e-28 96.2 0.7 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain PRIMA1 PF16101.5 EER24260.1 - 0.92 9.6 11.7 6.9 6.7 11.7 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 PX PF00787.24 EER24261.1 - 1.6e-18 66.7 0.1 3.4e-18 65.7 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EER24261.1 - 2.1e-11 43.8 8.4 8.6e-06 25.5 0.6 2.1 2 0 0 2 2 2 2 Vps5 C terminal like Occludin_ELL PF07303.13 EER24261.1 - 0.059 14.1 1.9 1.5 9.6 0.0 3.1 3 0 0 3 3 3 0 Occludin homology domain DASH_Dad3 PF08656.10 EER24261.1 - 0.07 13.2 0.7 0.3 11.2 0.1 2.4 2 1 0 2 2 2 0 DASH complex subunit Dad3 Sec34 PF04136.15 EER24261.1 - 0.12 12.2 1.9 0.12 12.3 0.3 1.8 2 0 0 2 2 2 0 Sec34-like family DUF1664 PF07889.12 EER24261.1 - 0.31 11.1 2.9 4.3 7.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BAR PF03114.18 EER24261.1 - 2.4 7.7 8.3 4.3 6.9 5.0 2.4 2 1 0 2 2 2 0 BAR domain BRE1 PF08647.11 EER24261.1 - 8.2 6.6 7.1 2 8.5 0.5 2.5 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase FAD_binding_3 PF01494.19 EER24262.1 - 1.5e-17 63.9 0.7 8.3e-16 58.2 0.7 2.8 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EER24262.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 EER24262.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EER24262.1 - 0.016 14.2 0.6 0.024 13.7 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EER24262.1 - 0.024 14.9 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EER24262.1 - 0.027 13.6 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EER24262.1 - 0.042 13.1 0.0 0.068 12.4 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EER24262.1 - 0.09 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EER24262.1 - 0.12 11.2 0.0 0.28 10.0 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase tRNA-synt_His PF13393.6 EER24263.1 - 3.8e-35 121.6 0.0 6.8e-29 101.1 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EER24263.1 - 7.3e-10 38.9 0.0 5.6e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EER24263.1 - 8.5e-06 25.9 0.0 1.8e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EER24263.1 - 0.03 13.4 0.0 0.083 12.0 0.0 1.8 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 EER24263.1 - 0.082 12.4 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs APH PF01636.23 EER24264.1 - 2.4e-15 57.1 0.2 4.3e-15 56.3 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER24264.1 - 0.00056 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EER24265.1 - 0.00028 20.9 0.2 0.00052 20.0 0.2 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DNA_pol_E_B PF04042.16 EER24266.1 - 0.077 12.3 0.1 0.093 12.1 0.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B UCH PF00443.29 EER24268.1 - 2.5e-57 194.3 0.0 2.5e-57 194.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER24268.1 - 5.4e-25 88.7 1.4 1.5e-19 70.8 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EER24268.1 - 0.013 15.0 1.5 0.013 15.0 1.5 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Glyco_hydro_46 PF01374.18 EER24268.1 - 0.21 11.2 3.4 0.45 10.1 3.4 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 DDHD PF02862.17 EER24268.1 - 4.5 7.4 7.8 3.6 7.7 3.7 2.3 2 0 0 2 2 2 0 DDHD domain Glyco_transf_22 PF03901.17 EER24269.1 - 1.5e-43 149.6 16.0 2e-43 149.2 16.0 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.14 EER24270.1 - 1.8e-68 231.7 21.0 2.7e-35 122.5 1.7 2.0 2 0 0 2 2 2 2 Dynamitin DHR10 PF18595.1 EER24270.1 - 0.0062 16.6 1.7 0.0062 16.6 1.7 3.4 3 0 0 3 3 3 1 Designed helical repeat protein 10 domain Jnk-SapK_ap_N PF09744.9 EER24270.1 - 0.025 14.8 18.3 0.059 13.6 1.2 3.0 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EER24270.1 - 0.035 14.6 20.2 0.95 10.0 7.0 3.6 3 0 0 3 3 3 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 EER24270.1 - 0.052 13.5 8.4 1.3 9.0 0.2 2.6 2 0 0 2 2 2 0 Axonemal dynein light chain DivIC PF04977.15 EER24270.1 - 0.067 13.0 16.8 0.14 12.0 1.7 3.7 3 0 0 3 3 3 0 Septum formation initiator DNA_pol3_tau_4 PF12168.8 EER24270.1 - 0.073 13.6 0.3 0.073 13.6 0.3 2.9 3 0 0 3 3 1 0 DNA polymerase III subunits tau domain IV DnaB-binding FapA PF03961.13 EER24270.1 - 0.11 11.1 6.6 0.45 9.0 0.1 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A SlyX PF04102.12 EER24270.1 - 0.13 12.9 16.0 0.21 12.2 2.3 4.5 4 2 0 4 4 3 0 SlyX Mod_r PF07200.13 EER24270.1 - 0.17 12.0 13.8 0.25 11.5 0.9 2.9 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Golgin_A5 PF09787.9 EER24270.1 - 0.29 10.6 11.4 0.41 10.1 0.7 2.4 2 0 0 2 2 2 0 Golgin subfamily A member 5 Cob_adeno_trans PF01923.18 EER24270.1 - 0.29 11.3 14.2 2.1 8.5 2.5 3.2 2 1 0 3 3 3 0 Cobalamin adenosyltransferase SKA2 PF16740.5 EER24270.1 - 0.29 10.9 8.9 0.48 10.2 0.0 3.5 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Spc24 PF08286.11 EER24270.1 - 0.29 11.4 12.9 2.1 8.6 3.7 3.1 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 End3 PF12761.7 EER24270.1 - 0.35 11.0 10.5 0.19 11.8 4.3 2.6 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Prefoldin_2 PF01920.20 EER24270.1 - 0.38 10.7 11.0 0.54 10.2 0.3 3.1 3 0 0 3 3 2 0 Prefoldin subunit Snapin_Pallidin PF14712.6 EER24270.1 - 0.48 10.9 8.7 0.38 11.2 0.1 3.7 4 0 0 4 4 3 0 Snapin/Pallidin DUF5069 PF16798.5 EER24270.1 - 0.48 10.6 6.8 7 6.9 0.4 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF5069) Prominin PF05478.11 EER24270.1 - 0.56 8.1 4.6 0.32 8.9 0.3 2.0 2 0 0 2 2 2 0 Prominin FH2 PF02181.23 EER24270.1 - 0.58 9.2 5.8 1.1 8.2 0.2 2.3 2 0 0 2 2 2 0 Formin Homology 2 Domain Cnn_1N PF07989.11 EER24270.1 - 0.66 10.2 11.4 2 8.6 1.3 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 YabA PF06156.13 EER24270.1 - 0.71 10.5 6.3 21 5.8 1.2 3.2 3 0 0 3 3 3 0 Initiation control protein YabA Fmp27_WPPW PF10359.9 EER24270.1 - 0.79 8.5 9.0 1.9 7.2 0.4 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain ADIP PF11559.8 EER24270.1 - 1 9.5 17.6 12 6.0 0.5 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2203 PF09969.9 EER24270.1 - 1.1 9.9 17.3 1.5 9.6 1.1 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Spc7 PF08317.11 EER24270.1 - 1.7 7.4 17.0 0.81 8.5 3.0 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein DUF3708 PF12501.8 EER24270.1 - 3.8 7.3 8.9 1.7 8.4 4.8 2.3 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter TMPIT PF07851.13 EER24270.1 - 3.9 6.6 6.5 7.2 5.8 0.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein TPR_MLP1_2 PF07926.12 EER24270.1 - 4.2 7.4 24.5 0.067 13.3 3.2 3.8 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein GrpE PF01025.19 EER24270.1 - 4.3 7.0 11.2 3.8 7.2 2.8 2.8 3 0 0 3 3 3 0 GrpE COG2 PF06148.11 EER24270.1 - 6.5 6.9 11.8 0.89 9.6 1.1 2.8 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Aldedh PF00171.22 EER24272.1 - 2.6e-137 458.1 0.6 3.1e-137 457.8 0.6 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.18 EER24273.1 - 4.9e-171 568.6 26.4 5e-171 568.5 19.7 2.0 2 0 0 2 2 2 2 Calreticulin family DUF1911 PF08929.10 EER24273.1 - 0.084 13.7 0.0 0.19 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1911) Aldolase_II PF00596.21 EER24274.1 - 7e-44 150.0 0.0 8e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.10 EER24275.1 - 3.3e-90 301.8 5.8 5.3e-90 301.1 5.8 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EER24275.1 - 8.6e-26 90.1 0.3 2.2e-25 88.8 0.0 1.9 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 EER24275.1 - 0.0074 16.0 6.1 0.025 14.3 1.9 2.3 1 1 1 2 2 2 1 BAR domain of APPL family BAR PF03114.18 EER24275.1 - 0.02 14.5 6.8 0.056 13.1 5.5 2.0 2 0 0 2 2 2 0 BAR domain FAM92 PF06730.11 EER24275.1 - 0.14 11.5 2.9 0.18 11.2 1.9 1.6 2 0 0 2 2 2 0 FAM92 protein Ribosomal_L31 PF01197.18 EER24276.1 - 0.068 13.4 0.2 0.14 12.4 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L31 Ribosomal_L37ae PF01780.19 EER24276.1 - 0.078 13.1 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Ribosomal L37ae protein family Flavin_Reduct PF01613.18 EER24277.1 - 1.9e-24 86.4 0.3 5.8e-24 84.9 0.3 1.7 1 1 0 1 1 1 1 Flavin reductase like domain POTRA_2 PF08479.11 EER24278.1 - 0.15 12.0 0.2 0.45 10.4 0.2 1.8 1 0 0 1 1 1 0 POTRA domain, ShlB-type SesA PF17107.5 EER24278.1 - 3.7 7.7 9.0 0.99 9.6 5.1 1.9 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases 4HBT_2 PF13279.6 EER24279.1 - 4.5e-12 46.5 0.0 7.3e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Methyltransf_25 PF13649.6 EER24280.1 - 2.8e-10 40.8 0.0 4.9e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER24280.1 - 1.1e-07 32.3 0.0 2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER24280.1 - 2.7e-05 24.1 0.0 7.1e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER24280.1 - 0.0003 20.2 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Exo_endo_phos PF03372.23 EER24281.1 - 3.4e-21 75.8 0.0 2e-20 73.4 0.0 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EER24281.1 - 2.7e-14 52.7 30.3 4.4e-08 32.8 7.6 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EER24281.1 - 2.4e-11 43.7 10.7 3.3e-07 30.5 2.8 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) TFIIA PF03153.13 EER24281.1 - 0.76 9.7 17.9 1.2 9.1 17.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_1 PF00560.33 EER24281.1 - 1.6 9.6 9.7 2.3 9.1 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat MFS_1 PF07690.16 EER24282.1 - 1e-35 123.3 51.9 3.1e-35 121.8 51.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EER24282.1 - 3.8e-17 62.0 17.3 3.8e-17 62.0 17.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER24282.1 - 2.1e-11 43.4 12.7 2.1e-11 43.4 12.7 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter Hydrolase_4 PF12146.8 EER24283.1 - 4.5e-50 170.1 0.0 8.8e-50 169.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EER24283.1 - 2.4e-13 51.2 3.3 3.1e-13 50.8 3.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER24283.1 - 1.5e-08 34.6 6.0 4.1e-07 29.9 2.9 2.8 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EER24283.1 - 5.6e-07 29.6 0.0 0.34 10.7 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase DLH PF01738.18 EER24283.1 - 0.0047 16.5 0.2 0.014 14.9 0.1 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Chlorophyllase2 PF12740.7 EER24283.1 - 0.0062 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 EER24283.1 - 0.027 14.1 0.0 0.11 12.1 0.0 2.0 2 1 1 3 3 3 0 Putative esterase Chlorophyllase PF07224.11 EER24283.1 - 0.028 13.4 0.1 0.052 12.6 0.1 1.3 1 1 0 1 1 1 0 Chlorophyllase DUF1749 PF08538.10 EER24283.1 - 0.033 13.3 0.1 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.13 EER24283.1 - 0.061 13.2 0.1 0.28 11.0 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 EER24283.1 - 0.089 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 EER24283.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GCD14 PF08704.10 EER24284.1 - 6.5e-05 22.7 0.0 0.033 13.9 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 EER24284.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.6 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Metallophos PF00149.28 EER24285.1 - 1.2e-18 68.4 0.5 2.2e-18 67.5 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EER24285.1 - 5.6e-06 26.7 0.0 8.1e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_1 PF00175.21 EER24286.1 - 7.6e-06 26.5 0.0 0.0022 18.6 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EER24286.1 - 0.00013 22.2 0.3 0.0042 17.2 0.3 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Baculo_11_kDa PF06143.11 EER24289.1 - 0.16 11.6 3.8 2.9 7.5 0.2 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family LapA_dom PF06305.11 EER24289.1 - 1 9.2 4.2 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Sigma_reg_N PF13800.6 EER24289.1 - 4.5 7.6 0.0 4.5 7.6 0.0 2.8 3 1 0 3 3 3 0 Sigma factor regulator N-terminal E1-E2_ATPase PF00122.20 EER24290.1 - 5.3e-48 162.9 0.9 5.3e-48 162.9 0.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 EER24290.1 - 7.1e-45 151.3 3.2 8.3e-11 42.2 0.0 4.9 5 0 0 5 5 5 4 Heavy-metal-associated domain Hydrolase PF00702.26 EER24290.1 - 2.2e-35 122.8 0.4 4.4e-35 121.9 0.4 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EER24290.1 - 0.00053 19.8 0.8 0.0021 17.9 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF678 PF05077.12 EER24290.1 - 0.092 12.9 7.9 3.3 7.9 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF678) PCI PF01399.27 EER24291.1 - 0.00062 20.2 0.0 0.001 19.5 0.0 1.3 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 EER24291.1 - 0.0018 18.2 0.1 0.0029 17.5 0.1 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain RGS PF00615.19 EER24292.1 - 3.6e-12 46.6 0.0 2.9e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.25 EER24293.1 - 1.1e-23 83.0 0.9 2.3e-23 82.1 0.9 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EER24293.1 - 5.3e-08 33.1 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER24293.1 - 4.5e-07 29.9 0.1 8.3e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER24293.1 - 0.00027 21.3 0.1 0.00054 20.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rad1 PF02144.16 EER24294.1 - 1.6e-88 296.4 0.0 1.9e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SbcCD_C PF13558.6 EER24295.1 - 1.2e-06 28.7 0.0 3.8e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit EzrA PF06160.12 EER24295.1 - 0.00049 18.4 12.6 0.00049 18.4 12.6 5.6 2 2 3 5 5 5 3 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 EER24295.1 - 0.0021 18.2 1.6 0.0021 18.2 1.6 13.6 6 3 10 16 16 16 5 ABC transporter C-terminal domain BAF PF02961.14 EER24295.1 - 0.06 13.8 2.4 0.36 11.3 0.5 2.9 2 0 0 2 2 2 0 Barrier to autointegration factor Sugarporin_N PF11471.8 EER24295.1 - 0.069 13.1 0.2 0.069 13.1 0.2 4.8 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension PPP4R2 PF09184.11 EER24296.1 - 7.2e-12 45.5 0.2 2.1e-11 43.9 0.2 2.0 1 1 0 1 1 1 1 PPP4R2 Occludin_ELL PF07303.13 EER24297.1 - 0.073 13.8 1.6 0.19 12.5 1.6 1.8 1 0 0 1 1 1 0 Occludin homology domain DUF155 PF02582.14 EER24298.1 - 2.5e-54 184.0 0.0 4e-54 183.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 zf-C2H2 PF00096.26 EER24299.1 - 1.6e-19 69.1 28.5 3.8e-05 23.9 1.8 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER24299.1 - 4e-17 61.8 26.1 1.4e-06 28.5 1.5 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER24299.1 - 7.1e-10 38.9 25.7 0.0042 17.8 1.2 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER24299.1 - 6.6e-06 26.3 2.3 0.4 11.0 0.1 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EER24299.1 - 0.0055 17.3 8.2 0.11 13.2 0.7 3.3 3 1 1 4 4 3 2 FOXP coiled-coil domain zf-met PF12874.7 EER24299.1 - 0.0074 16.6 11.9 0.3 11.5 0.2 4.0 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EER24299.1 - 0.0074 16.4 0.6 2.8 8.1 0.1 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_11 PF16622.5 EER24299.1 - 0.026 14.3 0.7 0.026 14.3 0.7 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF4764 PF15961.5 EER24299.1 - 0.04 12.6 0.2 0.04 12.6 0.2 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4764) zf_UBZ PF18439.1 EER24299.1 - 0.1 12.2 2.3 0.96 9.1 0.2 2.7 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger HNH PF01844.23 EER24299.1 - 2.4 8.4 8.3 17 5.7 0.1 4.1 4 0 0 4 4 4 0 HNH endonuclease BolA PF01722.18 EER24299.1 - 2.4 8.5 6.1 4.6 7.6 0.1 2.9 3 0 0 3 3 2 0 BolA-like protein zf-CRD PF17979.1 EER24299.1 - 2.9 8.0 7.7 5.5 7.1 1.5 2.3 1 1 1 2 2 2 0 Cysteine rich domain with multizinc binding regions Zn-ribbon_8 PF09723.10 EER24299.1 - 8.7 6.6 7.8 19 5.5 0.8 3.2 1 1 3 4 4 4 0 Zinc ribbon domain Methyltransf_23 PF13489.6 EER24300.1 - 2.2e-16 60.1 0.0 3.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER24300.1 - 1.8e-12 47.7 0.0 1.4e-05 25.6 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EER24300.1 - 1.5e-11 44.9 0.0 3.5e-11 43.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER24300.1 - 3.8e-10 40.3 0.0 9.8e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EER24300.1 - 3.6e-07 30.1 0.0 1.6e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EER24300.1 - 0.018 14.3 0.0 5.6 6.2 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase NNMT_PNMT_TEMT PF01234.17 EER24300.1 - 0.2 10.8 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family p450 PF00067.22 EER24301.1 - 8.8e-75 252.2 0.0 1e-74 252.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.20 EER24302.1 - 8.7e-37 126.4 6.6 2.3e-31 108.7 0.3 3.5 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EER24302.1 - 1.1e-29 103.4 4.0 1.1e-29 103.4 4.0 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EER24302.1 - 5.8e-23 80.8 0.0 1.2e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EER24302.1 - 2.9e-18 66.9 0.1 3.8e-17 63.3 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EER24302.1 - 3.2e-12 46.0 0.0 1.1e-11 44.3 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EER24302.1 - 1.7e-05 24.7 0.7 0.0013 18.5 0.7 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase BRAP2 PF07576.12 EER24303.1 - 1.4e-33 115.1 0.0 2.6e-33 114.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EER24303.1 - 1.1e-20 73.7 3.5 3.3e-20 72.2 3.5 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EER24303.1 - 3.9e-08 33.5 9.5 3.9e-08 33.5 9.5 2.9 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER24303.1 - 1.2e-05 25.0 9.4 1.2e-05 25.0 9.4 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EER24303.1 - 0.00087 19.5 6.9 0.00087 19.5 6.9 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EER24303.1 - 0.0011 18.8 8.6 0.0011 18.8 8.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER24303.1 - 0.0012 18.6 5.9 0.0012 18.6 5.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EER24303.1 - 0.0014 18.3 5.9 0.0014 18.3 5.9 3.0 4 0 0 4 4 3 1 RING-like zinc finger zf-RING_5 PF14634.6 EER24303.1 - 0.0014 18.5 7.7 0.0014 18.5 7.7 2.7 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EER24303.1 - 0.0019 18.2 6.0 0.0019 18.2 6.0 2.8 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_6 PF14835.6 EER24303.1 - 0.0037 17.1 2.1 0.0037 17.1 2.1 2.0 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EER24303.1 - 0.011 15.7 5.5 0.028 14.5 5.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ZapB PF06005.12 EER24303.1 - 0.014 15.8 0.5 0.014 15.8 0.5 2.7 1 1 1 2 2 1 0 Cell division protein ZapB ERM PF00769.19 EER24303.1 - 0.015 15.1 17.1 0.023 14.5 17.1 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family CCCAP PF15964.5 EER24303.1 - 0.17 10.2 11.6 0.24 9.7 11.6 1.1 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family JIP_LZII PF16471.5 EER24303.1 - 0.2 11.8 7.8 1.6 9.0 0.1 2.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II TolA_bind_tri PF16331.5 EER24303.1 - 0.48 10.5 2.2 0.55 10.4 0.5 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation SKA2 PF16740.5 EER24303.1 - 0.65 9.8 9.5 0.67 9.8 1.5 2.3 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Prok-RING_4 PF14447.6 EER24303.1 - 0.84 9.5 21.0 0.16 11.9 10.0 3.4 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 CtIP_N PF10482.9 EER24303.1 - 0.93 9.5 12.6 15 5.7 11.0 2.5 2 1 0 2 2 1 0 Tumour-suppressor protein CtIP N-terminal domain Exonuc_VII_L PF02601.15 EER24303.1 - 1.2 8.6 5.1 2.1 7.8 5.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-K PF11802.8 EER24303.1 - 2.2 7.8 8.3 7.7 6.0 7.8 1.8 1 1 1 2 2 2 0 Centromere-associated protein K TPR_MLP1_2 PF07926.12 EER24303.1 - 2.5 8.2 20.8 4.3 7.4 20.8 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein FUSC PF04632.12 EER24303.1 - 5 5.5 5.3 7 5.0 5.3 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HALZ PF02183.18 EER24303.1 - 9.5 6.5 7.7 6.1 7.2 0.2 2.7 3 0 0 3 3 2 0 Homeobox associated leucine zipper ubiquitin PF00240.23 EER24304.1 - 1.6e-134 437.8 21.6 4e-33 113.0 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EER24304.1 - 6.9e-63 208.4 22.6 3e-15 55.8 0.8 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EER24304.1 - 1.5e-22 79.8 11.6 0.00043 20.7 0.2 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EER24304.1 - 6.5e-16 58.0 4.4 0.03 14.3 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EER24304.1 - 3.3e-14 53.0 8.3 0.048 14.0 0.1 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EER24304.1 - 3.6e-14 52.8 3.1 0.13 12.4 0.0 5.0 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EER24304.1 - 3.2e-13 50.1 2.0 0.29 11.7 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 EER24304.1 - 1.2e-09 38.2 1.0 1.2 8.9 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EER24304.1 - 7.7e-07 29.1 25.0 17 5.5 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain Methyltrans_RNA PF04452.14 EER24304.1 - 1.4e-06 27.8 0.7 1.4 8.2 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase DUF3861 PF12977.7 EER24304.1 - 2.5e-06 27.6 2.8 11 6.3 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 EER24304.1 - 6.2e-06 26.5 0.0 30 5.1 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Big_7 PF17957.1 EER24304.1 - 8.8e-06 26.4 0.2 35 5.3 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain Big_3_3 PF13750.6 EER24304.1 - 0.00011 21.9 0.1 32 4.1 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) NEAT PF05031.12 EER24304.1 - 0.00012 22.6 2.4 0.52 10.9 1.6 2.8 1 1 1 2 2 2 2 Iron Transport-associated domain UDP-g_GGTase PF06427.11 EER24304.1 - 0.00021 21.3 5.1 6.6 6.9 0.1 4.0 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 EER24304.1 - 0.00022 21.0 5.1 19 5.2 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF969 PF06149.12 EER24304.1 - 0.00022 20.7 0.0 19 4.6 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF969) DUF493 PF04359.14 EER24304.1 - 0.0021 18.6 0.1 1.3e+02 3.3 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF493) ACT_4 PF13291.6 EER24304.1 - 0.0026 18.3 1.1 1.2e+02 3.4 0.0 4.2 4 0 0 4 4 4 0 ACT domain Raf1_HTH PF18579.1 EER24304.1 - 0.0041 16.8 0.2 1e+02 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ORF11CD3 PF10549.9 EER24304.1 - 0.0047 17.0 0.0 91 3.3 0.0 4.6 4 0 0 4 4 4 0 ORF11CD3 domain YcgR_2 PF12945.7 EER24304.1 - 0.0069 16.5 6.5 46 4.3 0.1 4.2 4 0 0 4 4 4 0 Flagellar protein YcgR Phage-tail_1 PF09097.10 EER24304.1 - 0.087 12.6 1.1 1.3e+02 2.2 0.0 3.8 4 0 0 4 4 4 0 Baseplate structural protein, domain 1 Tash_PEST PF07708.11 EER24304.1 - 0.14 12.4 27.2 6.2 7.1 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif ProRS-C_2 PF09181.10 EER24304.1 - 0.14 12.3 5.8 1.1e+02 3.0 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Myosin_N PF02736.19 EER24304.1 - 0.2 11.5 6.3 1.1e+02 2.8 0.0 5.3 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain DMA PF03474.14 EER24304.1 - 0.29 10.8 4.0 1e+02 2.6 0.0 4.1 4 0 0 4 4 4 0 DMRTA motif Phage_sheath_1N PF17481.2 EER24304.1 - 0.88 10.1 9.4 4.9e+03 -2.0 9.4 4.0 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain FlgD_ig PF13860.6 EER24304.1 - 0.95 9.4 9.4 92 3.0 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Zn_clus PF00172.18 EER24305.1 - 0.0036 17.4 8.4 0.0089 16.1 8.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.21 EER24306.1 - 2.5e-35 119.9 31.4 4.1e-10 39.2 1.1 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat dsrm PF00035.26 EER24307.1 - 0.00024 21.8 0.0 0.00047 20.8 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EER24307.1 - 0.038 14.3 0.1 0.075 13.3 0.1 1.5 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 DEAD PF00270.29 EER24309.1 - 5.9e-45 153.2 0.4 1.1e-44 152.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER24309.1 - 3e-23 82.3 0.0 1.6e-22 79.9 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EER24309.1 - 1.8e-18 66.5 0.0 3.4e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EER24309.1 - 0.00032 20.7 0.0 0.0008 19.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EER24309.1 - 0.00078 18.7 0.4 0.0018 17.6 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase TRP PF06011.12 EER24310.1 - 3e-168 560.0 25.5 3.7e-168 559.7 25.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EER24310.1 - 2e-39 135.2 0.1 3.4e-39 134.4 0.1 1.4 1 0 0 1 1 1 1 ML-like domain CNDH2_N PF06278.11 EER24310.1 - 0.3 11.3 0.4 1.3 9.3 0.1 2.0 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal zf-U1 PF06220.12 EER24311.1 - 3.8e-06 26.6 1.0 5.1e-06 26.2 1.0 1.2 1 0 0 1 1 1 1 U1 zinc finger DUF3602 PF12223.8 EER24312.1 - 0.00027 21.5 0.5 0.00074 20.1 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3602) Actin PF00022.19 EER24313.1 - 7.3e-126 420.0 0.0 3.2e-125 417.9 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EER24313.1 - 0.19 10.5 0.0 2.3 6.9 0.0 2.5 1 1 0 1 1 1 0 MreB/Mbl protein Glyco_tran_28_C PF04101.16 EER24314.1 - 6.4e-18 65.3 0.0 1.5e-17 64.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 EER24314.1 - 0.014 14.2 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase GUN4_N PF16416.5 EER24314.1 - 0.055 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 ARM-like repeat domain, GUN4-N terminal MRP-S28 PF10213.9 EER24315.1 - 1.1e-44 151.8 0.0 2.1e-44 151.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein zf-PHD-like PF15446.6 EER24317.1 - 4.6e-63 211.8 8.5 9.4e-63 210.8 8.5 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EER24317.1 - 2.9e-53 180.8 0.1 4.5e-53 180.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 EER24317.1 - 2.3e-28 97.8 1.0 6.4e-28 96.4 1.0 1.9 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 EER24317.1 - 2.8e-17 63.1 0.0 7.1e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER24317.1 - 8.6e-09 35.6 0.0 2.2e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 EER24317.1 - 3.1e-05 23.8 13.9 6.2e-05 22.8 2.6 4.1 3 1 0 3 3 3 1 PHD-finger DUF1087 PF06465.13 EER24317.1 - 0.00015 21.8 0.2 0.00015 21.8 0.2 2.0 2 0 0 2 2 1 1 Domain of Unknown Function (DUF1087) HDA2-3 PF11496.8 EER24317.1 - 0.00017 20.9 1.3 0.00054 19.2 1.3 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 EER24317.1 - 0.00026 20.8 7.1 0.016 15.1 1.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 EER24317.1 - 0.012 15.4 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase DEAD_2 PF06733.15 EER24317.1 - 0.013 15.2 0.0 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 DEAD_2 Prok-RING_1 PF14446.6 EER24317.1 - 0.028 14.3 4.8 0.026 14.4 2.7 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 SnAC PF14619.6 EER24317.1 - 0.21 12.2 4.8 1.4 9.6 0.2 3.2 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex SpoU_methylase PF00588.19 EER24318.1 - 6.2e-26 91.3 0.0 1.3e-25 90.2 0.0 1.5 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EER24318.1 - 2.1e-12 47.1 0.0 3.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding SNF2_N PF00176.23 EER24319.1 - 8.3e-76 255.0 0.3 1.6e-75 254.0 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EER24319.1 - 9.7e-44 148.0 1.7 9.7e-44 148.0 1.7 2.4 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EER24319.1 - 6.7e-38 129.9 2.4 6.7e-38 129.9 2.4 4.0 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 EER24319.1 - 3.3e-18 66.0 0.4 1.8e-17 63.7 0.0 2.5 3 0 0 3 3 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER24319.1 - 8.2e-10 38.9 0.0 6.6e-09 36.0 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EER24319.1 - 0.00012 21.4 0.1 0.00068 18.9 0.0 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 EER24319.1 - 0.00034 20.4 0.0 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 EER24319.1 - 0.00053 19.8 0.0 0.0016 18.2 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EER24319.1 - 0.014 15.5 0.0 3.9 7.8 0.0 3.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain DUF1825 PF08855.10 EER24319.1 - 0.035 14.0 0.4 0.14 12.1 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Occludin_ELL PF07303.13 EER24319.1 - 0.11 13.2 5.5 0.63 10.8 5.5 2.3 1 0 0 1 1 1 0 Occludin homology domain Sporozoite_P67 PF05642.11 EER24319.1 - 0.89 7.6 6.5 0.35 8.9 1.3 2.2 2 0 0 2 2 2 0 Sporozoite P67 surface antigen DUF4588 PF15251.6 EER24320.1 - 0.0003 20.7 2.3 0.0003 20.7 2.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) gerPA PF10676.9 EER24320.1 - 0.04 14.2 0.5 2.9 8.2 0.1 2.6 2 0 0 2 2 2 0 Spore germination protein gerPA/gerPF Adap_comp_sub PF00928.21 EER24321.1 - 1.2e-58 198.6 0.0 1.6e-58 198.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EER24321.1 - 0.00048 20.1 0.0 0.00073 19.5 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldedh PF00171.22 EER24322.1 - 8.4e-78 261.9 0.0 1e-77 261.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Acetyltransf_3 PF13302.7 EER24323.1 - 4.9e-25 88.8 0.0 9e-25 88.0 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER24323.1 - 0.0012 19.0 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Pkinase PF00069.25 EER24324.1 - 1.1e-64 218.4 0.0 1.4e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24324.1 - 1.5e-35 122.7 0.0 2.1e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER24324.1 - 2.9e-05 23.0 0.0 4.4e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EER24324.1 - 0.006 16.5 0.0 0.15 12.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EER24324.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EER24324.1 - 0.027 13.4 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EER24324.1 - 0.046 13.3 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EER24324.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.6 EER24325.1 - 8.9e-87 290.0 0.0 8.9e-87 290.0 0.0 2.5 3 0 0 3 3 3 1 SH2 domain HTH_44 PF14641.6 EER24325.1 - 2.3e-36 124.7 1.2 2.3e-36 124.7 1.2 2.3 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EER24325.1 - 2.2e-30 105.1 0.1 4.4e-30 104.1 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EER24325.1 - 3.5e-29 101.5 0.0 1.5e-28 99.5 0.0 2.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EER24325.1 - 4.3e-19 68.9 21.9 4.3e-19 68.9 21.9 6.1 6 1 0 6 6 6 1 Acidic N-terminal SPT6 HHH_3 PF12836.7 EER24325.1 - 6.6e-06 26.3 0.0 0.00017 21.8 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif SH2 PF00017.24 EER24325.1 - 3e-05 24.0 0.0 0.0001 22.3 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 EER24325.1 - 4.8e-05 24.2 8.1 0.00028 21.7 3.5 4.3 3 1 0 3 3 3 1 HHH domain S1 PF00575.23 EER24325.1 - 0.0036 17.6 0.0 0.018 15.4 0.0 2.3 2 0 0 2 2 2 1 S1 RNA binding domain Tex_YqgF PF16921.5 EER24325.1 - 0.015 15.8 0.0 0.046 14.2 0.0 1.9 2 0 0 2 2 2 0 Tex protein YqgF-like domain IFRD PF05004.13 EER24326.1 - 2.6e-80 269.8 3.5 3.7e-80 269.3 3.5 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) CoiA PF06054.11 EER24326.1 - 0.11 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Competence protein CoiA-like family FdhD-NarQ PF02634.15 EER24327.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 FdhD/NarQ family SOG2 PF10428.9 EER24328.1 - 0.062 12.5 15.4 0.069 12.3 15.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 EER24328.1 - 2.7 6.5 13.3 3.7 6.0 13.3 1.2 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 EER24330.1 - 2e-46 158.6 24.4 2e-46 158.6 24.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER24330.1 - 1.1e-16 60.8 1.1 1.1e-16 60.8 1.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EER24330.1 - 0.00069 18.2 2.0 0.00099 17.6 2.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EER24330.1 - 0.21 9.8 5.1 0.79 7.9 1.3 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Gly_kinase PF02595.15 EER24331.1 - 1.8e-133 445.1 2.2 2e-133 444.9 2.2 1.0 1 0 0 1 1 1 1 Glycerate kinase family ABC2_membrane PF01061.24 EER24332.1 - 2.6e-69 232.9 69.5 1.5e-38 132.3 28.7 4.6 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EER24332.1 - 2e-38 132.0 0.0 2.7e-18 66.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EER24332.1 - 1.7e-29 101.5 13.3 1.4e-25 89.0 0.1 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EER24332.1 - 7.8e-18 64.9 0.1 2.9e-17 63.1 0.0 2.1 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EER24332.1 - 1.2e-07 31.2 11.0 1.2e-07 31.2 11.0 3.5 2 2 1 3 3 2 1 ABC-2 family transporter protein AAA_25 PF13481.6 EER24332.1 - 9.8e-07 28.5 0.1 3.3e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EER24332.1 - 3.7e-06 27.0 0.0 0.3 10.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EER24332.1 - 1e-05 25.7 0.1 0.0024 18.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EER24332.1 - 4.1e-05 24.0 0.1 0.0018 18.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EER24332.1 - 4.7e-05 23.0 1.3 0.0026 17.5 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EER24332.1 - 6.8e-05 22.8 0.2 0.0034 17.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EER24332.1 - 7.5e-05 23.3 0.1 0.0025 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EER24332.1 - 0.0075 15.7 0.2 0.068 12.6 0.0 2.4 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EER24332.1 - 0.01 16.1 1.2 0.43 10.9 0.2 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EER24332.1 - 0.013 15.6 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EER24332.1 - 0.018 14.9 3.1 1 9.2 0.1 2.8 3 0 0 3 3 2 0 NACHT domain AAA_23 PF13476.6 EER24332.1 - 0.027 14.9 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EER24332.1 - 0.028 14.8 0.2 0.62 10.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EER24332.1 - 0.03 13.9 2.2 0.041 13.5 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EER24332.1 - 0.034 13.9 0.4 0.96 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EER24332.1 - 0.11 12.3 0.0 0.85 9.4 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_28 PF13521.6 EER24332.1 - 0.13 12.5 0.6 0.41 10.9 0.3 2.0 2 0 0 2 2 1 0 AAA domain Pax2_C PF12403.8 EER24332.1 - 0.13 12.3 0.2 0.37 10.9 0.1 1.7 2 0 0 2 2 1 0 Paired-box protein 2 C terminal DnaB_C PF03796.15 EER24332.1 - 0.17 11.2 0.1 20 4.4 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain DUF3980 PF13140.6 EER24332.1 - 0.92 10.0 6.1 0.96 9.9 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) AMP-binding PF00501.28 EER24333.1 - 2.4e-75 253.7 0.0 3.2e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER24333.1 - 1.1e-15 58.4 0.1 2.2e-15 57.4 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cutinase PF01083.22 EER24336.1 - 8.4e-38 130.1 0.0 9.7e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Cutinase DIT1_PvcA PF05141.12 EER24339.1 - 5.8e-92 308.1 0.0 7.5e-92 307.7 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.22 EER24340.1 - 6.7e-57 193.2 0.0 7.8e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EER24341.1 - 5.2e-36 124.3 39.9 5.2e-36 124.3 39.9 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EER24341.1 - 6.3e-08 31.9 25.8 1.9e-07 30.3 25.4 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter CoA_transf_3 PF02515.17 EER24342.1 - 1.9e-41 142.5 0.0 5.3e-39 134.4 0.0 2.3 2 1 0 2 2 2 2 CoA-transferase family III RPAP1_C PF08620.10 EER24343.1 - 9.9e-23 80.0 0.0 2.1e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EER24343.1 - 7.8e-19 67.2 6.8 1.3e-18 66.5 6.8 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.10 EER24344.1 - 8.7e-08 32.0 0.0 2.2e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Phosphoesterase PF04185.14 EER24345.1 - 1.8e-75 254.3 0.7 2.7e-75 253.8 0.7 1.2 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.15 EER24346.1 - 2.6e-44 150.1 0.3 2.6e-42 143.6 0.0 3.5 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EER24346.1 - 2.9e-32 111.3 4.0 1.5e-30 105.7 0.9 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EER24346.1 - 2.3e-15 57.0 0.0 2.4e-14 53.8 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase DUF4637 PF15470.6 EER24346.1 - 0.039 13.7 0.6 0.063 13.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CDC45 PF02724.14 EER24346.1 - 0.44 8.8 1.6 0.57 8.4 1.6 1.1 1 0 0 1 1 1 0 CDC45-like protein ANAPC1 PF12859.7 EER24347.1 - 9.5e-32 110.3 1.1 3.1e-31 108.6 1.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EER24347.1 - 0.13 12.8 9.2 0.8 10.3 0.0 4.9 5 0 0 5 5 5 0 Proteasome/cyclosome repeat UBA2_C PF16195.5 EER24348.1 - 0.024 15.3 2.9 0.024 15.3 2.9 2.3 3 0 0 3 3 3 0 SUMO-activating enzyme subunit 2 C-terminus PIP5K PF01504.18 EER24349.1 - 2.6e-101 338.5 0.3 2.6e-101 338.5 0.3 2.0 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase SUIM_assoc PF16619.5 EER24349.1 - 0.074 13.1 5.6 0.27 11.3 1.6 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HemY_N PF07219.13 EER24349.1 - 2.4 8.4 3.4 1.4 9.1 0.2 2.2 2 0 0 2 2 2 0 HemY protein N-terminus SelP_N PF04592.14 EER24349.1 - 5.2 6.4 13.7 12 5.2 13.7 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Linker_histone PF00538.19 EER24350.1 - 2.8e-28 98.1 0.1 2.8e-28 98.1 0.1 2.3 2 1 0 2 2 2 1 linker histone H1 and H5 family Mitofilin PF09731.9 EER24350.1 - 3.5 6.4 24.9 3.5 6.3 24.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Peptidase_M35 PF02102.15 EER24352.1 - 2e-82 277.0 2.1 2.4e-82 276.7 2.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EER24352.1 - 1.9e-32 112.8 0.3 3e-32 112.2 0.3 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Pkinase PF00069.25 EER24353.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EER24353.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Dicty_CAR PF05462.11 EER24354.1 - 1.9e-11 43.7 10.5 1.9e-11 43.7 10.5 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 EER24354.1 - 3.3e-07 30.3 9.1 5.3e-07 29.6 9.1 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.24 EER24354.1 - 0.00042 19.7 8.0 0.00062 19.1 8.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 EER24354.1 - 0.0011 18.4 3.0 0.0015 17.9 3.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) XPG_I PF00867.18 EER24355.1 - 8.2e-32 109.4 0.0 8.2e-32 109.4 0.0 2.2 3 0 0 3 3 3 1 XPG I-region XPG_N PF00752.17 EER24355.1 - 1.6e-19 70.3 0.4 5.9e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EER24355.1 - 1.8e-05 25.2 0.5 0.00013 22.4 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HXXSHH PF07586.11 EER24355.1 - 0.96 9.0 6.9 0.6 9.6 4.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1552) Glyoxalase_4 PF13669.6 EER24356.1 - 0.00017 21.8 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EER24356.1 - 0.00049 20.3 0.0 0.001 19.2 0.0 1.5 2 0 0 2 2 2 1 Glyoxalase-like domain Acyl-CoA_dh_N PF02771.16 EER24357.1 - 1.3e-26 93.5 0.1 2.4e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EER24357.1 - 5.7e-24 85.0 0.7 8.4e-24 84.5 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EER24357.1 - 1.3e-16 60.6 0.0 2.6e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EER24357.1 - 3.2e-07 30.7 0.4 6e-07 29.8 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.26 EER24358.1 - 1.4e-52 177.1 0.0 1.6e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER24358.1 - 0.0047 16.6 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EER24358.1 - 0.036 14.3 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EER24358.1 - 0.045 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain Gly-zipper_Omp PF13488.6 EER24359.1 - 0.022 14.7 4.8 0.049 13.6 4.8 1.5 1 0 0 1 1 1 0 Glycine zipper Glyoxalase PF00903.25 EER24359.1 - 0.029 14.5 0.0 0.32 11.2 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rick_17kDa_Anti PF05433.15 EER24359.1 - 0.18 11.7 6.4 0.43 10.5 6.4 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 EER24359.1 - 0.32 10.8 8.2 0.7 9.7 8.2 1.6 1 0 0 1 1 1 0 Glycine-zipper domain EMG1 PF03587.14 EER24360.1 - 3.8e-79 264.9 0.0 4.5e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Acetyltransf_13 PF13880.6 EER24361.1 - 1.1e-26 92.5 0.0 4.1e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EER24361.1 - 1.3e-14 53.7 0.2 2.4e-14 52.8 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DUF4741 PF15897.5 EER24361.1 - 0.0041 16.9 0.1 0.0078 16.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4741) eIF2A PF08662.11 EER24364.1 - 9.7e-83 276.8 0.0 6.9e-82 274.0 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EER24364.1 - 0.018 15.9 1.6 1.9 9.5 0.1 4.2 4 1 0 5 5 5 0 WD domain, G-beta repeat DPPIV_N PF00930.21 EER24364.1 - 0.04 12.7 0.0 4.3 6.0 0.0 2.3 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Cytochrom_D1 PF02239.16 EER24364.1 - 0.099 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.12 EER24364.1 - 0.26 11.3 1.1 44 4.2 0.1 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Macoilin PF09726.9 EER24364.1 - 1.4 7.4 11.1 2 6.9 11.1 1.1 1 0 0 1 1 1 0 Macoilin family NAD_binding_6 PF08030.12 EER24365.1 - 1.8e-32 112.6 0.0 8.7e-32 110.4 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EER24365.1 - 5.5e-22 77.9 0.0 1.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EER24365.1 - 9.9e-19 67.7 12.0 9.9e-19 67.7 12.0 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EER24365.1 - 0.1 13.2 0.0 0.51 11.0 0.0 2.3 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EER24365.1 - 0.15 12.4 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain CorA PF01544.18 EER24366.1 - 5.8e-15 55.4 0.3 1.1e-14 54.4 0.3 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TFIID_20kDa PF03847.13 EER24367.1 - 3.8e-21 75.3 0.0 8.7e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Zip PF02535.22 EER24367.1 - 6 6.0 4.9 8.6 5.5 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Baculo_PP31 PF05311.11 EER24367.1 - 6.3 6.2 17.3 13 5.1 17.3 1.5 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SpoIIP PF07454.11 EER24367.1 - 7.2 6.0 15.8 19 4.6 15.8 1.7 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Allexi_40kDa PF05549.11 EER24367.1 - 9.7 5.6 12.1 27 4.2 12.1 1.7 1 0 0 1 1 1 0 Allexivirus 40kDa protein DASH_Spc34 PF08657.10 EER24368.1 - 1.1e-31 110.6 7.6 2.2e-21 76.9 6.8 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF5082 PF16888.5 EER24368.1 - 0.0014 18.9 0.3 0.0014 18.9 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF5082) Tnp_22_trimer PF17489.2 EER24368.1 - 0.0067 16.4 0.1 3.4 7.7 0.0 2.8 2 0 0 2 2 2 2 L1 transposable element trimerization domain DUF465 PF04325.13 EER24368.1 - 0.01 15.9 1.9 0.018 15.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) FmdA_AmdA PF03069.15 EER24368.1 - 0.15 10.9 0.1 0.25 10.2 0.1 1.3 1 0 0 1 1 1 0 Acetamidase/Formamidase family TMF_DNA_bd PF12329.8 EER24368.1 - 0.17 11.9 4.8 0.24 11.4 0.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 EER24368.1 - 0.19 12.1 2.0 0.58 10.6 0.1 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.6 EER24368.1 - 0.27 11.7 2.2 8.9 6.8 0.3 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Tropomyosin_1 PF12718.7 EER24368.1 - 0.46 10.6 8.1 5.4 7.2 8.3 2.2 1 1 0 1 1 1 0 Tropomyosin like SlyX PF04102.12 EER24368.1 - 0.65 10.7 5.8 0.48 11.1 0.4 2.7 2 1 0 2 2 2 0 SlyX DHR10 PF18595.1 EER24368.1 - 1.2 9.2 11.3 2.5 8.2 2.3 2.4 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DASH_Spc19 PF08287.11 EER24368.1 - 1.4 8.8 7.8 0.29 11.0 4.1 1.7 2 0 0 2 2 2 0 Spc19 Rpn3_C PF08375.11 EER24369.1 - 6.2e-27 93.8 1.5 2e-26 92.2 1.5 1.9 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EER24369.1 - 6.4e-21 74.8 0.3 6.9e-20 71.5 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 EER24369.1 - 0.022 14.9 0.0 0.067 13.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat SWI-SNF_Ssr4 PF08549.10 EER24369.1 - 0.5 9.0 8.3 0.94 8.0 8.3 1.4 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) polyprenyl_synt PF00348.17 EER24370.1 - 2.9e-69 233.0 0.0 9.3e-69 231.3 0.0 1.7 1 1 0 1 1 1 1 Polyprenyl synthetase Ank_2 PF12796.7 EER24371.1 - 1.3e-23 83.4 2.1 3.3e-08 34.0 0.1 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER24371.1 - 1.8e-21 76.2 2.4 1.3e-08 35.2 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EER24371.1 - 8.3e-20 70.6 6.0 2e-05 24.8 0.6 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EER24371.1 - 8.7e-19 67.1 2.5 0.0088 16.5 0.2 4.7 4 1 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EER24371.1 - 2.3e-17 61.3 3.1 0.002 18.5 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat QWRF PF04484.12 EER24371.1 - 0.15 11.7 2.6 0.53 10.0 0.1 2.0 2 0 0 2 2 2 0 QWRF family BPL_LplA_LipB PF03099.19 EER24372.1 - 0.00031 20.7 0.0 0.00054 19.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.22 EER24373.1 - 2.7e-53 179.9 0.0 3.1e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER24373.1 - 9.1e-22 77.5 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER24373.1 - 2.4e-08 33.6 0.0 3.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EER24373.1 - 0.00026 20.4 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EER24373.1 - 0.0053 16.2 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EER24373.1 - 0.014 14.5 0.0 0.023 13.9 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 EER24373.1 - 0.038 14.1 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER24373.1 - 0.063 13.2 0.0 8.2 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase IpgD PF05925.12 EER24373.1 - 0.17 10.4 0.0 0.21 10.1 0.0 1.0 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD CWC25 PF12542.8 EER24374.1 - 2.5e-26 92.6 0.5 2.5e-26 92.6 0.5 3.6 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 EER24374.1 - 5.5e-13 48.9 8.3 5.5e-13 48.9 8.3 3.5 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR PCI PF01399.27 EER24375.1 - 2.6e-18 66.5 0.1 7.3e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 PCI domain TPR_11 PF13414.6 EER24375.1 - 0.0044 16.7 0.8 0.033 13.9 0.1 2.6 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.28 EER24375.1 - 0.0057 16.4 2.8 0.038 13.8 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EER24375.1 - 0.0089 16.1 5.3 0.03 14.4 0.1 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EER24375.1 - 0.0093 15.9 0.3 0.33 11.1 0.1 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EER24375.1 - 0.03 14.6 0.2 0.45 10.8 0.0 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EER24375.1 - 0.18 12.7 0.1 5 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EER24375.1 - 0.68 10.3 4.7 6.6 7.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_C65 PF10275.9 EER24376.1 - 6.2e-60 202.7 0.0 7.4e-60 202.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Putative_PNPOx PF01243.20 EER24377.1 - 9e-13 48.2 0.0 3.1e-12 46.5 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase NIPSNAP PF07978.13 EER24378.1 - 2.9e-40 136.6 0.3 5.1e-29 100.5 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP SR-25 PF10500.9 EER24378.1 - 0.16 11.5 18.8 0.27 10.8 18.0 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein H-kinase_dim PF02895.14 EER24378.1 - 0.69 10.4 2.8 18 5.8 2.0 2.6 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain FAM199X PF15814.5 EER24378.1 - 0.72 8.8 11.0 1 8.4 11.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X Macoilin PF09726.9 EER24378.1 - 1.9 6.9 6.7 2.5 6.6 6.7 1.1 1 0 0 1 1 1 0 Macoilin family Chorion_2 PF03964.15 EER24378.1 - 2.7 8.9 10.1 3.3 8.6 8.7 1.8 2 0 0 2 2 2 0 Chorion family 2 Apt1 PF10351.9 EER24378.1 - 3.2 6.5 7.5 4.3 6.1 7.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF755 PF05501.11 EER24378.1 - 7.5 6.9 19.3 2.8 8.2 15.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) CDP-OH_P_transf PF01066.21 EER24379.1 - 2.3e-17 63.5 0.1 2.3e-17 63.5 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DUF308 PF03729.13 EER24379.1 - 0.085 13.2 0.5 0.085 13.2 0.5 3.8 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF4064 PF13273.6 EER24379.1 - 3 8.2 7.0 0.62 10.4 0.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Ribosomal_S27e PF01667.17 EER24380.1 - 1e-28 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 EER24380.1 - 0.37 10.8 6.6 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type FSH1 PF03959.13 EER24381.1 - 1.4e-65 220.9 0.0 5e-65 219.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PCI PF01399.27 EER24382.1 - 4.9e-21 75.2 0.0 1.9e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EER24382.1 - 2.7e-15 56.2 0.4 7e-15 54.8 0.4 1.8 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain PMC2NT PF08066.12 EER24382.1 - 0.076 13.7 0.4 2.8 8.7 0.1 3.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain TP_methylase PF00590.20 EER24383.1 - 2.7e-48 164.8 0.2 4.6e-48 164.0 0.2 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EER24383.1 - 7.2e-14 52.1 0.0 1.3e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EER24383.1 - 4.4e-12 45.5 0.0 5.2e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EER24383.1 - 3.6e-10 39.1 0.0 6.8e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central DUF2973 PF11189.8 EER24385.1 - 0.013 15.5 1.0 0.2 11.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) DUF4834 PF16118.5 EER24385.1 - 0.051 14.5 0.0 0.097 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Melittin PF01372.17 EER24386.1 - 0.067 13.2 0.6 43 4.3 0.0 3.2 3 0 0 3 3 3 0 Melittin ABC_tran PF00005.27 EER24387.1 - 5.8e-46 156.4 0.0 2.8e-22 79.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EER24387.1 - 5.9e-29 101.6 8.0 5.9e-29 101.6 8.0 3.5 2 1 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 EER24387.1 - 9.9e-10 38.7 2.8 0.071 12.9 0.0 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EER24387.1 - 1.6e-09 37.5 5.1 0.043 13.3 1.4 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EER24387.1 - 2.3e-09 37.6 0.5 0.0061 16.8 0.2 3.5 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EER24387.1 - 2.2e-07 31.4 0.3 0.0059 17.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EER24387.1 - 3.1e-06 26.8 1.1 0.046 13.5 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 EER24387.1 - 5.2e-06 26.9 0.0 0.0073 16.7 0.0 3.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EER24387.1 - 7.3e-06 26.2 0.0 0.00076 19.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EER24387.1 - 8.4e-06 25.9 0.0 0.2 11.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 EER24387.1 - 1.5e-05 24.2 0.1 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein cobW PF02492.19 EER24387.1 - 5.9e-05 22.7 0.3 0.023 14.3 0.1 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EER24387.1 - 7.1e-05 22.8 0.3 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 EER24387.1 - 0.00019 21.0 0.4 0.061 12.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_23 PF13476.6 EER24387.1 - 0.00056 20.5 0.6 0.26 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EER24387.1 - 0.00064 20.3 0.1 0.61 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EER24387.1 - 0.0013 18.7 0.2 0.067 13.2 0.0 2.8 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EER24387.1 - 0.0016 18.2 0.7 0.32 10.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EER24387.1 - 0.0033 17.4 1.0 0.54 10.1 0.0 3.4 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 EER24387.1 - 0.0056 15.6 0.1 0.67 8.8 0.1 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 EER24387.1 - 0.006 16.7 2.7 0.035 14.2 0.2 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 EER24387.1 - 0.0097 16.0 3.3 0.19 11.8 0.1 2.9 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.18 EER24387.1 - 0.013 14.9 1.4 0.79 9.0 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 EER24387.1 - 0.018 14.9 1.1 1.2 9.1 0.1 2.7 2 0 0 2 2 2 0 NTPase GTP_EFTU PF00009.27 EER24387.1 - 0.024 14.2 0.0 3 7.3 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.14 EER24387.1 - 0.026 14.5 0.4 4.3 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EER24387.1 - 0.029 13.7 0.0 0.79 9.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.18 EER24387.1 - 0.03 13.6 0.0 0.61 9.3 0.0 2.2 2 0 0 2 2 2 0 Septin MobB PF03205.14 EER24387.1 - 0.033 14.1 3.3 1.3 8.9 0.0 3.5 4 0 0 4 4 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.13 EER24387.1 - 0.044 12.9 0.1 11 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 EER24387.1 - 0.044 13.5 1.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.22 EER24387.1 - 0.048 12.8 5.5 0.23 10.6 0.3 3.3 2 2 0 2 2 2 0 NB-ARC domain ATP_bind_1 PF03029.17 EER24387.1 - 0.054 13.3 0.6 0.99 9.1 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.6 EER24387.1 - 0.074 13.3 0.7 13 6.1 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EER24387.1 - 0.078 12.7 0.3 0.59 9.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_15 PF13175.6 EER24387.1 - 0.08 12.6 0.2 12 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 EER24387.1 - 0.081 12.7 0.2 4.9 6.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EER24387.1 - 0.1 13.0 0.1 11 6.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 EER24387.1 - 0.14 12.2 0.0 5.7 7.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EER24387.1 - 0.22 11.9 0.8 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EER24387.1 - 0.29 10.7 1.0 11 5.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 EER24387.1 - 0.49 10.3 5.4 0.84 9.5 0.1 2.9 3 0 0 3 3 2 0 NACHT domain Roc PF08477.13 EER24387.1 - 0.57 10.4 4.2 10 6.4 0.0 3.3 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase DeoC PF01791.9 EER24388.1 - 1.5e-17 64.1 1.8 1.8e-17 63.7 1.8 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 EER24388.1 - 0.022 14.0 0.4 0.032 13.5 0.4 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.21 EER24388.1 - 0.048 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Methyltrn_RNA_3 PF02598.17 EER24389.1 - 1.4e-108 362.8 0.0 1.6e-108 362.5 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase WD40 PF00400.32 EER24390.1 - 7.2e-13 48.8 6.2 2.2e-06 28.3 0.1 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 EER24390.1 - 0.00075 18.3 0.0 0.036 12.7 0.0 2.4 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Gon7 PF08738.10 EER24390.1 - 0.015 15.3 2.6 0.04 14.0 2.6 1.7 1 0 0 1 1 1 0 Gon7 family Pox_A11 PF05061.13 EER24390.1 - 0.078 12.2 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Lzipper-MIP1 PF14389.6 EER24390.1 - 0.098 13.0 2.8 0.1 12.9 1.0 2.0 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 TMF_TATA_bd PF12325.8 EER24390.1 - 0.61 10.3 7.8 1.1 9.5 7.8 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LIAS_N PF16881.5 EER24391.1 - 1.9e-25 89.4 0.0 4e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EER24391.1 - 3.3e-16 60.1 0.0 5.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.7 EER24392.1 - 1.8e-20 74.2 0.0 2.9e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EER24392.1 - 3.3e-18 66.7 0.1 4.4e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EER24392.1 - 4.5e-08 33.1 0.0 2.8e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EER24392.1 - 0.00011 22.4 0.0 0.00071 19.7 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EER24392.1 - 0.00021 20.8 0.0 0.0011 18.5 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.12 EER24392.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) PAPS_reduct PF01507.19 EER24393.1 - 4e-43 147.5 0.0 7.2e-43 146.6 0.0 1.4 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.17 EER24394.1 - 7.3e-86 287.0 0.0 1e-85 286.5 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EER24394.1 - 1.9e-59 200.1 0.1 3e-59 199.4 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EER24394.1 - 1.4e-53 180.8 0.0 2.5e-53 180.0 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.12 EER24394.1 - 0.068 13.0 0.0 0.31 10.9 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TPR_12 PF13424.6 EER24395.1 - 0.003 17.8 0.2 1.2 9.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat YfkD PF14167.6 EER24395.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 YfkD-like protein PEHE PF15275.6 EER24395.1 - 0.45 11.2 2.6 1.3 9.6 2.6 1.8 1 0 0 1 1 1 0 PEHE domain AA_permease_2 PF13520.6 EER24396.1 - 7.6e-52 176.6 46.3 9.7e-52 176.2 46.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER24396.1 - 3.9e-25 88.4 40.7 5.3e-25 88.0 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4592 PF15262.6 EER24399.1 - 0.0071 17.0 0.3 0.01 16.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4592) Complex1_LYR PF05347.15 EER24400.1 - 1.1e-17 63.7 6.3 1.6e-17 63.3 6.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EER24400.1 - 0.00023 21.8 3.1 0.00027 21.6 3.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Glutaredoxin2_C PF04399.13 EER24400.1 - 0.062 13.1 0.4 0.073 12.9 0.4 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain SET PF00856.28 EER24402.1 - 3.9e-14 53.4 0.3 3.9e-14 53.4 0.3 3.8 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EER24402.1 - 1.6e-07 31.2 5.4 1.6e-07 31.2 5.4 2.3 2 0 0 2 2 2 1 AWS domain DHHC PF01529.20 EER24403.1 - 2.8e-33 114.9 7.0 2.8e-33 114.9 7.0 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase B12D PF06522.11 EER24404.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit PMT PF02366.18 EER24405.1 - 1.7e-82 276.7 17.3 3.6e-82 275.6 17.3 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EER24405.1 - 1.8e-67 226.8 15.9 1.8e-67 226.8 15.9 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EER24405.1 - 7.3e-48 162.9 0.1 1.5e-47 161.8 0.1 1.5 1 0 0 1 1 1 1 MIR domain Ubiquitin_2 PF14560.6 EER24405.1 - 0.069 13.6 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain PRP21_like_P PF12230.8 EER24406.1 - 3e-59 200.5 12.9 5.5e-58 196.4 12.9 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EER24406.1 - 4.4e-40 135.5 4.2 5.4e-21 74.3 0.2 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EER24406.1 - 0.0076 15.8 0.7 0.019 14.5 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Sec2p PF06428.11 EER24407.1 - 1e-29 102.3 14.7 1e-29 102.3 14.7 2.7 1 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF5401 PF17380.2 EER24407.1 - 0.12 10.5 19.7 0.18 9.9 19.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF3584 PF12128.8 EER24407.1 - 0.29 8.6 22.7 0.41 8.1 22.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF5339 PF17274.2 EER24407.1 - 2.6 8.9 18.6 1.1 10.2 1.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5339) dsDNA_bind PF01984.20 EER24408.1 - 7.3e-41 138.9 11.4 8.5e-41 138.7 11.4 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Fes1 PF08609.10 EER24408.1 - 0.066 14.1 1.1 0.1 13.5 0.2 1.7 1 1 1 2 2 2 0 Nucleotide exchange factor Fes1 Tom5 PF10642.9 EER24408.1 - 0.076 13.1 0.6 0.076 13.1 0.6 1.8 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase Orbi_VP5 PF00901.17 EER24408.1 - 0.25 9.7 2.4 0.31 9.4 2.4 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Coq4 PF05019.13 EER24409.1 - 1.4e-99 331.9 0.0 1.7e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.28 EER24410.1 - 4.6e-15 56.4 0.0 8.7e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 SET domain ApbA_C PF08546.11 EER24411.1 - 8e-34 116.5 0.5 1.2e-33 116.0 0.5 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EER24411.1 - 7.4e-27 93.9 0.1 1e-25 90.2 0.1 2.1 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 EER24412.1 - 5.9e-17 62.1 1.2 1.5e-16 60.8 1.2 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF2076 PF09849.9 EER24413.1 - 4.6e-08 33.4 12.7 5.4e-08 33.2 12.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EER24413.1 - 1.8e-06 27.9 2.2 3.1e-06 27.2 2.2 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EER24413.1 - 0.1 12.6 1.0 0.17 12.0 1.0 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UBX PF00789.20 EER24414.1 - 5.8e-13 48.8 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 UBX domain Tox-GHH PF15636.6 EER24414.1 - 0.027 14.5 6.6 0.04 13.9 3.6 2.4 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin GET2 PF08690.10 EER24414.1 - 4.9 6.7 7.7 8.7 5.9 7.7 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Amidase PF01425.21 EER24415.1 - 1.4e-70 238.5 0.0 5.5e-70 236.6 0.0 1.7 1 1 0 1 1 1 1 Amidase SURF1 PF02104.15 EER24416.1 - 1.1e-45 156.0 0.0 1.6e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 EER24417.1 - 7.3e-29 100.1 0.0 1.5e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EER24417.1 - 1.1e-05 25.8 0.0 2.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EER24417.1 - 1.2e-05 25.6 0.1 2.4e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EER24417.1 - 0.028 14.7 0.0 0.053 13.8 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CMS1 PF14617.6 EER24418.1 - 6e-78 261.7 4.2 7.3e-78 261.4 4.2 1.1 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EER24418.1 - 0.00058 19.7 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase TT_ORF2 PF02957.15 EER24418.1 - 0.38 11.7 2.5 0.64 10.9 2.5 1.3 1 0 0 1 1 1 0 TT viral ORF2 RRM_1 PF00076.22 EER24419.1 - 3.1e-12 46.1 1.3 1.1e-11 44.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.22 EER24420.1 - 6.3e-55 185.2 0.0 7.2e-55 185.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER24420.1 - 8.7e-21 74.4 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER24420.1 - 5.2e-08 32.5 0.0 6.6e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EER24420.1 - 0.0077 15.8 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABM PF03992.16 EER24421.1 - 2.1e-10 40.6 0.1 1.3e-06 28.4 0.0 2.1 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase RhoGAP PF00620.27 EER24422.1 - 3.7e-48 163.2 0.4 1.2e-47 161.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EER24422.1 - 1.5e-13 50.8 4.2 8.2e-13 48.4 0.3 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain OmpH PF03938.14 EER24422.1 - 0.23 11.8 16.1 10 6.4 15.4 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DMPK_coil PF08826.10 EER24422.1 - 5.6 7.2 7.7 4.4 7.5 0.8 3.1 2 1 1 3 3 3 0 DMPK coiled coil domain like SSF PF00474.17 EER24423.1 - 0.022 13.6 21.4 0.23 10.2 21.4 2.3 1 1 0 1 1 1 0 Sodium:solute symporter family DUF5453 PF17534.2 EER24423.1 - 2.4 8.1 6.3 0.32 11.0 1.7 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5453) Tim44 PF04280.15 EER24424.1 - 4.6e-06 26.8 0.0 7.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 EER24424.1 - 1.9e-05 23.8 0.0 2.8e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein EOS1 PF12326.8 EER24425.1 - 4.6e-13 49.5 13.4 1.8e-12 47.6 10.2 2.0 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.22 EER24426.1 - 1.8e-28 98.8 3.5 2.4e-28 98.5 3.5 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 EER24426.1 - 0.047 13.9 0.3 0.075 13.3 0.3 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain ANAPC5 PF12862.7 EER24427.1 - 5.5e-34 116.1 2.5 5.5e-34 116.1 2.5 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EER24427.1 - 9e-05 22.7 12.6 0.03 14.6 0.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER24427.1 - 0.0017 18.4 1.7 15 6.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EER24427.1 - 0.0042 16.9 4.9 1.4 8.9 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EER24427.1 - 0.01 16.3 3.1 0.16 12.5 0.2 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 EER24427.1 - 0.031 14.3 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_7 PF13176.6 EER24427.1 - 0.092 12.8 2.7 4.6 7.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EER24427.1 - 0.36 11.6 5.5 5.2 8.0 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EER24427.1 - 1.5 9.0 4.5 18 5.6 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat SAICAR_synt PF01259.18 EER24428.1 - 9e-98 326.9 0.0 1.1e-97 326.7 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase CIA30 PF08547.12 EER24429.1 - 2.3e-39 135.0 0.0 1.8e-24 86.6 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Med12 PF09497.10 EER24430.1 - 1.3e-27 95.9 0.2 3.6e-27 94.4 0.2 1.9 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 MMM1 PF10296.9 EER24431.1 - 3e-06 26.5 0.1 1.4e-05 24.4 0.0 2.0 1 1 1 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 EER24431.1 - 0.00036 20.9 0.3 0.0022 18.4 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain ANTH PF07651.16 EER24432.1 - 4.9e-77 258.6 0.0 4.9e-77 258.6 0.0 2.9 2 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 EER24432.1 - 3.6e-56 189.7 9.0 3.6e-56 189.7 9.0 6.4 3 2 5 8 8 8 2 I/LWEQ domain HMG_box PF00505.19 EER24434.1 - 2.8e-20 72.5 0.8 4.9e-20 71.7 0.8 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EER24434.1 - 9.5e-06 26.1 0.1 1.8e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 EER24434.1 - 0.059 12.7 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Elf-1_N PF12310.8 EER24434.1 - 0.12 12.9 0.2 0.23 12.0 0.2 1.4 1 0 0 1 1 1 0 Transcription factor protein N terminal Exo_endo_phos PF03372.23 EER24435.1 - 6.4e-12 45.5 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EER24435.1 - 6e-05 23.0 1.4 0.00015 21.8 1.4 1.7 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.15 EER24436.1 - 7.4e-54 181.0 0.5 8.6e-54 180.8 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Mannosyl_trans3 PF11051.8 EER24437.1 - 1.8e-39 135.8 0.0 2.6e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative UPF0139 PF03669.13 EER24439.1 - 0.00019 21.2 0.5 0.048 13.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0139) Methyltransf_23 PF13489.6 EER24440.1 - 4.4e-14 52.6 0.0 7.4e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER24440.1 - 6.7e-12 46.0 0.0 1.3e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER24440.1 - 2.1e-10 41.1 0.0 4.3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER24440.1 - 1.8e-07 31.8 0.0 1.3e-06 29.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER24440.1 - 3.6e-07 30.1 0.0 1.4e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER24440.1 - 0.0012 18.4 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EER24440.1 - 0.0098 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.18 EER24440.1 - 0.041 13.2 0.0 0.24 10.7 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EER24440.1 - 0.052 12.8 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 EER24440.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DNA_pol_B PF00136.21 EER24441.1 - 6.8e-101 338.2 0.0 9.1e-101 337.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EER24441.1 - 3.8e-24 85.5 0.0 1.2e-13 50.9 0.1 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EER24441.1 - 4.2e-19 68.8 7.6 4.2e-19 68.8 7.6 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF4612 PF15389.6 EER24441.1 - 0.17 13.0 0.2 0.57 11.3 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) Slu7 PF11708.8 EER24442.1 - 2.6e-85 286.4 20.5 2.6e-85 286.4 20.5 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Bud13 PF09736.9 EER24442.1 - 0.01 16.2 2.2 0.01 16.2 2.2 3.7 3 1 0 4 4 4 0 Pre-mRNA-splicing factor of RES complex zf-CCHC_4 PF14392.6 EER24442.1 - 0.072 12.8 0.6 0.072 12.8 0.6 1.7 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_L37e PF01907.19 EER24443.1 - 3.1e-29 100.9 11.5 4.7e-29 100.3 11.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EER24443.1 - 0.028 14.4 1.1 0.042 13.9 1.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 EER24443.1 - 0.07 13.2 0.4 0.094 12.7 0.4 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF35_N PF12172.8 EER24443.1 - 0.3 11.0 5.1 0.57 10.1 5.1 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2688 PF10892.8 EER24443.1 - 0.41 10.1 5.3 9.5 5.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) ELP6 PF09807.9 EER24444.1 - 2.5e-14 53.3 0.0 3.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 2 Elongation complex protein 6 ATPase PF06745.13 EER24444.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 KaiC RdRP PF05183.12 EER24445.1 - 2.7e-194 647.1 0.0 3.9e-194 646.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 EER24445.1 - 0.0019 18.0 0.0 0.0058 16.4 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.19 EER24446.1 - 4.2e-64 216.6 0.0 7.3e-64 215.8 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EER24446.1 - 8.7e-35 119.5 0.0 2.2e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Semialdhyde_dhC PF02774.18 EER24447.1 - 4.4e-33 114.9 0.0 5.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EER24447.1 - 2.1e-28 99.2 0.0 4.3e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_S4e PF00900.20 EER24448.1 - 4.9e-37 125.7 0.2 9.3e-37 124.8 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EER24448.1 - 2.5e-24 84.6 0.0 4.2e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EER24448.1 - 1.2e-18 66.9 7.0 2.4e-18 65.9 7.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EER24448.1 - 7.8e-06 25.5 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EER24448.1 - 0.0047 16.8 1.5 0.0047 16.8 1.5 3.2 4 0 0 4 4 4 1 KOW motif RasGEF PF00617.19 EER24449.1 - 6.1e-05 23.3 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF domain Myb_DNA-bind_6 PF13921.6 EER24450.1 - 1.4e-15 57.3 0.0 7.6e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EER24450.1 - 1.2e-12 47.7 0.1 3.6e-06 27.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EER24450.1 - 0.025 14.6 0.0 7.4 6.6 0.0 2.5 2 0 0 2 2 2 0 SLIDE PX PF00787.24 EER24451.1 - 5.1e-27 94.1 0.1 6.2e-27 93.8 0.1 1.1 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 EER24452.1 - 1e-19 70.5 18.0 0.00031 21.5 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EER24452.1 - 0.00012 20.7 0.4 4.2 5.8 0.0 4.1 3 1 1 4 4 4 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EER24452.1 - 0.0061 16.8 0.0 0.098 13.0 0.0 3.0 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EER24452.1 - 0.014 15.9 0.4 32 5.2 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain WD40_like PF17005.5 EER24452.1 - 0.017 14.5 0.1 2.2 7.5 0.0 3.0 4 0 0 4 4 4 0 WD40-like domain Glyoxal_oxid_N PF07250.11 EER24452.1 - 0.027 13.7 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus SecE PF00584.20 EER24453.1 - 9.5e-14 51.1 0.0 1.2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_1 PF00076.22 EER24454.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EER24454.1 - 0.075 13.3 0.8 0.13 12.5 0.8 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Pyr_redox_2 PF07992.14 EER24455.1 - 1.2e-15 57.5 0.1 1.1e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER24455.1 - 5.6e-13 48.8 1.9 6.7e-12 45.3 1.4 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EER24455.1 - 1.5e-11 43.5 0.1 2e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EER24455.1 - 3.2e-07 29.8 0.1 4e-06 26.2 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EER24455.1 - 1.8e-05 25.2 0.3 0.29 11.7 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EER24455.1 - 3.9e-05 23.0 0.0 0.00072 18.9 0.1 2.4 2 1 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 EER24455.1 - 0.0001 22.4 0.1 0.00032 20.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EER24455.1 - 0.00023 20.3 0.6 0.0046 16.1 0.2 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EER24455.1 - 0.00027 19.8 0.1 0.0014 17.5 0.2 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EER24455.1 - 0.00047 19.4 3.2 0.0066 15.6 1.3 2.3 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EER24455.1 - 0.0007 19.0 0.2 0.34 10.3 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 EER24455.1 - 0.0025 17.1 0.2 0.012 14.9 0.0 2.1 3 0 0 3 3 3 1 Thi4 family AlaDh_PNT_C PF01262.21 EER24455.1 - 0.005 16.2 0.2 0.035 13.4 0.1 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EER24455.1 - 0.019 14.0 0.0 0.042 12.9 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EER24455.1 - 0.028 14.0 3.0 0.97 8.9 0.5 3.0 2 1 0 2 2 2 0 FAD dependent oxidoreductase XdhC_C PF13478.6 EER24455.1 - 0.06 13.8 0.1 9.1 6.8 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 EER24455.1 - 0.071 13.4 0.1 0.75 10.1 0.0 2.4 3 0 0 3 3 3 0 TrkA-N domain FAD_oxidored PF12831.7 EER24455.1 - 0.27 10.6 4.3 0.082 12.2 1.5 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DBD_Tnp_Mut PF03108.15 EER24456.1 - 6.2e-13 48.5 0.1 1.2e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 MuDR family transposase WRKY PF03106.15 EER24456.1 - 0.19 12.0 1.1 0.35 11.1 1.1 1.4 1 0 0 1 1 1 0 WRKY DNA -binding domain Mito_carr PF00153.27 EER24457.1 - 4.8e-72 238.0 1.1 1.2e-23 82.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EER24457.1 - 0.029 13.5 0.1 0.44 9.7 0.0 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease DUF4244 PF14029.6 EER24457.1 - 7.7 6.0 6.9 0.9 9.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) Ribosomal_L21e PF01157.18 EER24458.1 - 2.6e-46 155.6 8.3 2.8e-46 155.5 6.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L21e DUF5486 PF17588.2 EER24458.1 - 0.28 11.1 2.9 1.6 8.7 0.8 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5486) S4 PF01479.25 EER24459.1 - 5.8e-13 48.3 1.6 5.8e-13 48.3 1.6 2.4 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EER24459.1 - 1.5e-06 29.0 0.4 3.1e-06 28.0 0.3 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Kre28 PF17097.5 EER24460.1 - 0.00062 18.8 1.8 0.0008 18.5 1.8 1.4 1 0 0 1 1 1 1 Spindle pole body component BLOC1_2 PF10046.9 EER24460.1 - 0.00078 19.7 1.3 0.00078 19.7 1.3 3.2 5 0 0 5 5 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.11 EER24460.1 - 0.0028 17.9 5.4 0.0056 16.9 0.6 3.1 4 1 1 5 5 3 1 Bacterial protein of unknown function (DUF948) APP_amyloid PF10515.9 EER24460.1 - 0.01 16.3 0.3 0.026 15.0 0.0 1.9 2 0 0 2 2 1 1 Beta-amyloid precursor protein C-terminus MAD PF05557.13 EER24460.1 - 0.019 13.3 6.8 0.032 12.6 6.8 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein Fez1 PF06818.15 EER24460.1 - 0.04 14.4 11.0 0.15 12.5 11.0 1.9 1 1 0 1 1 1 0 Fez1 MCPsignal PF00015.21 EER24460.1 - 0.051 13.4 2.0 0.13 12.0 0.5 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cob_adeno_trans PF01923.18 EER24460.1 - 0.064 13.4 4.8 0.086 13.0 1.9 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase DUF3450 PF11932.8 EER24460.1 - 0.071 12.4 7.2 0.4 10.0 1.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3103 PF11301.8 EER24460.1 - 0.074 11.8 1.2 0.32 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3103) DUF1043 PF06295.12 EER24460.1 - 0.13 12.2 4.3 0.15 12.1 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) OmpH PF03938.14 EER24460.1 - 0.14 12.5 5.9 0.87 9.9 1.2 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ABC_tran_CTD PF16326.5 EER24460.1 - 0.19 12.0 23.0 0.074 13.3 2.9 5.4 5 1 1 6 6 4 0 ABC transporter C-terminal domain Atg14 PF10186.9 EER24460.1 - 0.23 10.5 11.3 2.1 7.4 11.4 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EER24460.1 - 0.24 10.2 15.7 0.065 12.1 4.2 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein Prefoldin PF02996.17 EER24460.1 - 0.27 11.2 9.3 0.31 11.0 1.9 3.4 2 1 2 4 4 4 0 Prefoldin subunit Baculo_PEP_C PF04513.12 EER24460.1 - 0.43 10.6 3.9 1.1 9.3 1.4 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FemAB PF02388.16 EER24460.1 - 0.51 9.2 4.5 0.26 10.1 2.2 1.6 1 1 0 1 1 1 0 FemAB family CdvA PF18822.1 EER24460.1 - 0.54 10.1 7.2 5.2 6.9 2.2 3.1 2 1 1 3 3 3 0 CdvA-like coiled-coil domain HMMR_N PF15905.5 EER24460.1 - 0.67 9.4 10.5 4.1 6.8 10.5 2.0 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Mod_r PF07200.13 EER24460.1 - 1.5 8.9 10.9 0.31 11.2 4.6 2.4 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2203 PF09969.9 EER24460.1 - 2.9 8.6 8.1 9.1 7.0 0.7 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) FAM76 PF16046.5 EER24460.1 - 3.4 6.9 5.9 7.2 5.9 2.8 1.9 1 1 1 2 2 2 0 FAM76 protein YabA PF06156.13 EER24460.1 - 5.6 7.7 5.5 24 5.6 1.0 3.3 2 1 1 3 3 3 0 Initiation control protein YabA ADIP PF11559.8 EER24460.1 - 6.5 6.8 13.0 4.3 7.4 3.1 3.3 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 EER24460.1 - 7 5.0 6.9 9.3 4.7 6.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GREB1 PF15782.5 EER24461.1 - 1.8 5.6 13.9 2.2 5.3 13.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Amidoligase_2 PF12224.8 EER24462.1 - 6.1e-14 52.3 0.0 1.6e-07 31.2 0.0 3.0 2 1 0 2 2 2 2 Putative amidoligase enzyme DOPA_dioxygen PF08883.11 EER24463.1 - 1.3e-43 147.5 0.1 1.6e-43 147.3 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Vps62 PF06101.11 EER24464.1 - 1.5e-13 50.0 1.0 6.5e-13 47.8 0.4 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 WD40 PF00400.32 EER24464.1 - 0.21 12.5 1.0 18 6.4 0.3 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Septin PF00735.18 EER24465.1 - 1.2e-28 100.2 0.0 2.2e-10 40.3 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 EER24465.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.23 EER24465.1 - 0.027 14.5 0.0 0.16 12.0 0.0 2.2 2 1 0 2 2 2 0 Dynamin family AAA_16 PF13191.6 EER24465.1 - 0.028 14.8 0.0 0.17 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 EER24465.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 EER24465.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Annexin PF00191.20 EER24466.1 - 2.8e-12 46.5 5.1 0.048 13.7 0.0 5.2 5 1 0 5 5 5 4 Annexin Polyoma_agno PF01736.16 EER24467.1 - 0.086 12.6 0.1 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Polyomavirus agnoprotein KRTDAP PF15200.6 EER24467.1 - 0.11 12.3 0.0 0.93 9.3 0.0 2.4 2 1 1 3 3 3 0 Keratinocyte differentiation-associated UPF0016 PF01169.19 EER24468.1 - 7.5e-41 138.3 24.4 1.2e-21 76.8 9.4 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EER24468.1 - 0.0052 16.6 0.1 0.0052 16.6 0.1 2.0 2 0 0 2 2 2 1 Putative manganese efflux pump TerC PF03741.16 EER24468.1 - 0.0079 15.9 1.3 0.018 14.7 1.3 1.6 1 0 0 1 1 1 1 Integral membrane protein TerC family DUF3357 PF11837.8 EER24468.1 - 1.1 9.8 8.3 2 8.9 0.1 3.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) CDC48_N PF02359.18 EER24470.1 - 0.16 12.1 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain MFS_1 PF07690.16 EER24471.1 - 5.7e-37 127.5 31.4 8.1e-37 127.0 27.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER24471.1 - 9.2e-16 57.7 3.7 9.2e-16 57.7 3.7 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EER24471.1 - 1.4e-05 23.7 3.8 2.8e-05 22.8 3.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gln-synt_C PF00120.24 EER24472.1 - 7.7e-59 199.4 0.0 3.4e-58 197.3 0.0 1.9 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.14 EER24472.1 - 1.7e-11 44.5 0.0 3.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Acetyltransf_1 PF00583.25 EER24473.1 - 8.3e-09 35.7 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER24473.1 - 6.3e-08 32.6 0.0 6.2e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER24473.1 - 9.5e-07 29.2 0.0 2.7e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER24473.1 - 0.00044 20.3 0.0 0.0029 17.7 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain US2 PF02476.15 EER24473.1 - 0.046 14.4 0.3 0.1 13.3 0.3 1.6 1 1 0 1 1 1 0 US2 family UPF0113 PF03657.13 EER24473.1 - 0.06 13.6 0.0 0.15 12.4 0.0 1.6 2 0 0 2 2 2 0 UPF0113 PUA domain FR47 PF08445.10 EER24473.1 - 0.11 12.5 0.0 0.41 10.7 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein Porin_1 PF00267.21 EER24473.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Gram-negative porin Acetyltransf_7 PF13508.7 EER24474.1 - 0.00083 19.7 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER24474.1 - 0.0016 18.6 0.0 0.0054 17.0 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EER24474.1 - 0.0086 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EER24474.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 EER24474.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.7 EER24474.1 - 0.21 11.5 0.0 0.55 10.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2235 PF09994.9 EER24475.1 - 1.2e-91 307.1 0.3 1.4e-91 306.8 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Aldedh PF00171.22 EER24476.1 - 2.4e-156 520.9 0.1 2.7e-156 520.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pectinesterase PF01095.19 EER24476.1 - 0.12 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase AA_permease_2 PF13520.6 EER24477.1 - 1.3e-42 146.2 52.6 1.6e-42 145.9 52.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER24477.1 - 6.1e-21 74.6 48.7 8.6e-21 74.1 48.7 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_18 PF00704.28 EER24478.1 - 4.5e-25 89.0 0.0 8e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3180 PF11377.8 EER24478.1 - 0.14 12.3 0.4 0.25 11.5 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) GPI2 PF06432.11 EER24480.1 - 6.6e-131 435.9 2.6 7.8e-131 435.6 2.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase REV PF00424.18 EER24480.1 - 0.093 12.8 1.3 0.21 11.7 1.3 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF346 PF03984.13 EER24481.1 - 6e-76 249.9 59.1 4.7e-13 48.6 3.0 7.2 7 0 0 7 7 7 7 Repeat of unknown function (DUF346) Ntox14 PF15522.6 EER24481.1 - 3.3e-05 23.4 0.0 28 4.0 0.0 6.3 7 0 0 7 7 7 1 Novel toxin 14 DUF2510 PF10708.9 EER24481.1 - 7.1e-05 22.5 50.8 0.091 12.5 2.2 6.0 6 0 0 6 6 6 5 Protein of unknown function (DUF2510) DUF1724 PF08350.10 EER24481.1 - 0.00036 20.6 1.5 9.5 6.4 0.0 4.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1724) Stap_Strp_toxin PF01123.20 EER24481.1 - 0.02 15.7 0.0 9.4 7.2 0.0 4.4 7 0 0 7 7 7 0 Staphylococcal/Streptococcal toxin, OB-fold domain DUF1010 PF06231.11 EER24481.1 - 1.3 9.6 0.0 1.3 9.6 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1010) Fumble PF03630.14 EER24482.1 - 1.1e-144 481.7 0.1 1.4e-144 481.3 0.1 1.1 1 0 0 1 1 1 1 Fumble Glyoxal_oxid_N PF07250.11 EER24483.1 - 2.3e-40 138.3 0.0 1.1e-39 136.1 0.0 2.0 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EER24483.1 - 1.4e-23 83.0 0.1 2.8e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.19 EER24483.1 - 4.7e-07 30.2 20.2 8.2e-07 29.4 20.2 1.4 1 0 0 1 1 1 1 Chitin recognition protein DEAD PF00270.29 EER24484.1 - 2.4e-43 147.9 0.0 1.1e-42 145.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER24484.1 - 2.3e-26 92.3 0.0 3.4e-25 88.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER24484.1 - 0.016 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 EER24484.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Acetyltransf_1 PF00583.25 EER24485.1 - 5.8e-07 29.8 0.0 1e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EER24485.1 - 0.0028 18.3 0.0 0.0044 17.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER24485.1 - 0.0032 17.9 0.0 0.008 16.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER24485.1 - 0.01 15.8 0.0 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pho86 PF11124.8 EER24485.1 - 0.019 14.4 0.2 0.037 13.5 0.1 1.5 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Sugar_tr PF00083.24 EER24486.1 - 8.2e-49 166.7 14.8 1.6e-48 165.7 14.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER24486.1 - 1.1e-18 67.4 23.3 1.1e-18 67.4 23.3 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Polysacc_deac_1 PF01522.21 EER24487.1 - 6e-21 74.6 0.0 1.4e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EER24487.1 - 0.007 16.0 0.1 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Glyco_hydro_57 PF03065.15 EER24487.1 - 0.036 13.3 0.0 0.15 11.2 0.0 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 DFP PF04127.15 EER24488.1 - 7.1e-13 48.8 0.0 1.2e-05 25.2 0.0 3.4 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein FleQ PF06490.11 EER24488.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar regulatory protein FleQ Atg29_N PF18388.1 EER24489.1 - 5.5e-21 74.1 2.4 1.3e-20 73.0 2.4 1.6 1 0 0 1 1 1 1 Atg29 N-terminal domain CENP-O PF09496.10 EER24491.1 - 1.2e-70 237.8 0.1 4e-70 236.1 0.0 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component PI3K_P85_iSH2 PF16454.5 EER24491.1 - 0.0074 15.9 0.6 0.18 11.4 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FTA4 PF13093.6 EER24491.1 - 0.014 15.3 0.6 0.028 14.3 0.6 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Acatn PF13000.7 EER24492.1 - 3.5e-161 537.4 18.9 9.5e-83 278.5 8.3 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.22 EER24493.1 - 8.9e-54 183.0 0.0 1.1e-53 182.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EER24494.1 - 5.5e-20 71.8 0.0 8.3e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER24494.1 - 6.4e-13 49.2 0.0 1.8e-12 47.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER24494.1 - 1.4e-11 44.4 0.0 1.2e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER24494.1 - 2.5e-09 37.7 0.0 5.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER24494.1 - 1.5e-07 32.1 0.0 3.6e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER24494.1 - 0.00054 19.4 0.0 0.0081 15.5 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EER24494.1 - 0.0051 16.3 0.0 0.024 14.1 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 EER24494.1 - 0.0096 16.0 0.0 0.027 14.6 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EER24494.1 - 0.02 14.2 0.0 0.24 10.7 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase domain MTS PF05175.14 EER24494.1 - 0.021 14.4 0.0 0.21 11.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 EER24494.1 - 0.028 13.7 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.12 EER24494.1 - 0.053 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) TRM PF02005.16 EER24494.1 - 0.063 12.4 0.0 0.097 11.8 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase CRM1_repeat PF18777.1 EER24494.1 - 0.18 11.4 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat STAG PF08514.11 EER24495.1 - 1.1e-39 134.8 0.8 1.1e-39 134.8 0.8 2.7 2 0 0 2 2 2 1 STAG domain HEAT PF02985.22 EER24495.1 - 0.033 14.5 2.6 24 5.5 0.2 5.0 5 0 0 5 5 5 0 HEAT repeat Goodbye PF17109.5 EER24495.1 - 0.4 11.1 2.2 7.1 7.1 0.1 3.6 3 0 0 3 3 3 0 fungal STAND N-terminal Goodbye domain UreD PF01774.17 EER24496.1 - 1.4e-74 250.6 0.0 1.6e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein S1 PF00575.23 EER24499.1 - 8.9e-69 227.8 20.1 5.7e-14 52.2 0.1 11.5 11 0 0 11 11 11 10 S1 RNA binding domain Suf PF05843.14 EER24499.1 - 3.8e-06 27.1 13.2 0.00047 20.2 0.0 4.9 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EER24499.1 - 5.7e-06 26.7 0.0 0.045 14.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EER24499.1 - 1.1e-05 25.9 0.0 0.17 12.8 0.2 5.0 3 2 2 5 5 5 1 Tetratricopeptide repeat S1_2 PF13509.6 EER24499.1 - 0.0027 17.8 0.2 5.2 7.2 0.0 4.7 4 0 0 4 4 4 1 S1 domain RNase_II_C_S1 PF18614.1 EER24499.1 - 0.0059 16.5 4.7 5.5 7.0 0.1 5.1 5 0 0 5 5 5 1 RNase II-type exonuclease C-terminal S1 domain TPR_16 PF13432.6 EER24499.1 - 0.05 14.3 0.0 9 7.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EER24499.1 - 0.071 13.4 0.0 9.5 6.7 0.0 3.3 2 1 0 2 2 2 0 PPR repeat TPR_6 PF13174.6 EER24499.1 - 0.12 13.0 0.0 1.9e+02 3.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 EER24500.1 - 1e-14 54.6 8.5 0.0017 19.1 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER24500.1 - 6.2e-09 36.0 0.0 0.064 13.6 0.0 6.1 4 2 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Sial-lect-inser PF09264.10 EER24500.1 - 0.013 15.2 0.0 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Vibrio cholerae sialidase, lectin insertion PQQ_3 PF13570.6 EER24500.1 - 0.11 13.0 0.1 3.7 8.2 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain WD40_like PF17005.5 EER24500.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Cpn60_TCP1 PF00118.24 EER24501.1 - 3.9e-151 504.0 15.2 4.4e-151 503.9 15.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ProRS-C_1 PF09180.11 EER24502.1 - 3e-21 75.4 3.6 5.3e-21 74.6 2.5 2.0 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EER24502.1 - 4.4e-19 69.1 0.0 7.8e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EER24502.1 - 4.7e-14 52.3 0.0 2e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain DUF1497 PF07384.11 EER24502.1 - 0.12 12.8 0.1 0.35 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1497) RNase_PH PF01138.21 EER24504.1 - 1e-24 87.5 0.0 3e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PEMT PF04191.13 EER24505.1 - 7.5e-58 193.5 14.4 4.9e-37 126.6 0.6 2.7 3 0 0 3 3 3 2 Phospholipid methyltransferase SKICH PF17751.1 EER24505.1 - 0.00035 21.1 0.1 0.029 14.9 0.1 2.5 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 EER24505.1 - 0.0019 18.0 0.1 0.005 16.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 ParA PF10609.9 EER24506.1 - 7.1e-96 320.4 0.0 8.3e-96 320.2 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EER24506.1 - 2.7e-07 30.7 0.0 1.4e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EER24506.1 - 6.8e-06 25.5 0.5 0.00018 20.8 0.1 2.5 1 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.6 EER24506.1 - 7.8e-06 25.9 0.0 1.7e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EER24506.1 - 0.0028 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 EER24506.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase MipZ PF09140.11 EER24506.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 1 0 1 1 1 0 ATPase MipZ AAA_26 PF13500.6 EER24506.1 - 0.035 13.9 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EER24506.1 - 0.041 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EER24506.1 - 0.068 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EER24506.1 - 0.089 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Ras PF00071.22 EER24506.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Ras family Fer4_NifH PF00142.18 EER24506.1 - 0.11 12.0 0.0 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.6 EER24506.1 - 0.12 12.8 0.0 0.21 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EER24506.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 EER24506.1 - 0.18 11.9 0.5 1.8 8.7 0.5 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 EER24506.1 - 0.2 10.7 0.1 0.3 10.1 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 EER24506.1 - 0.22 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EER24506.1 - 0.23 12.0 0.1 0.32 11.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain SKG6 PF08693.10 EER24507.1 - 0.016 14.6 1.6 0.038 13.4 1.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF347 PF03988.12 EER24507.1 - 0.07 13.3 1.8 0.24 11.6 1.8 1.9 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Asp PF00026.23 EER24509.1 - 2.5e-57 194.7 0.3 3e-57 194.4 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EER24509.1 - 2.5e-07 31.1 0.1 0.024 14.9 0.0 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EER24509.1 - 3e-06 27.8 1.3 0.0019 18.8 0.5 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EER24509.1 - 0.00065 20.2 0.2 0.061 13.9 0.1 3.0 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EER24509.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal tRNA_bind PF01588.20 EER24510.1 - 5e-20 71.4 4.0 9e-20 70.6 0.0 3.1 3 1 0 3 3 3 1 Putative tRNA binding domain GST_C_2 PF13410.6 EER24510.1 - 0.0003 20.7 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EER24510.1 - 0.0023 18.1 0.2 0.0067 16.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EER24510.1 - 0.079 13.2 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Anp1 PF03452.14 EER24511.1 - 8.4e-112 372.9 3.6 2e-111 371.7 0.0 2.1 2 0 0 2 2 2 1 Anp1 O-antigen_lig PF13425.6 EER24511.1 - 1.9 7.2 3.3 2.8 6.6 3.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Dcc1 PF09724.9 EER24512.1 - 1.2e-24 87.2 0.0 1.5e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Acetyltransf_9 PF13527.7 EER24513.1 - 4e-05 23.7 0.0 0.00013 22.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER24513.1 - 5.1e-05 23.6 0.0 9.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER24513.1 - 0.00073 19.5 0.0 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER24513.1 - 0.0011 19.2 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EER24513.1 - 0.016 15.2 0.0 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_15 PF17013.5 EER24513.1 - 0.091 12.2 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase IBR PF01485.21 EER24514.1 - 3.5e-06 27.1 7.1 3.5e-06 27.1 7.1 3.4 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain HORMA PF02301.18 EER24515.1 - 4.6e-10 39.4 0.0 7.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.19 EER24516.1 - 2.6e-08 33.7 2.4 1.5e-07 31.2 0.0 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EER24516.1 - 0.00044 20.3 0.5 0.0039 17.3 0.0 3.0 3 1 0 3 3 3 1 Exportin 1-like protein RIX1 PF08167.12 EER24516.1 - 0.0094 15.7 0.3 0.085 12.6 0.0 2.8 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.9 EER24516.1 - 0.028 13.0 0.2 0.13 10.7 0.0 2.1 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Adaptin_N PF01602.20 EER24516.1 - 0.069 11.7 0.1 0.43 9.1 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HEAT PF02985.22 EER24516.1 - 0.13 12.6 1.0 33 5.1 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat TetR_C_15 PF17918.1 EER24516.1 - 0.82 10.5 4.9 27 5.6 0.1 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Het-C PF07217.11 EER24517.1 - 1.5e-280 931.6 0.0 1.8e-280 931.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C DUF390 PF04094.14 EER24518.1 - 1.8 6.8 9.4 2.1 6.5 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) zf-RING_UBOX PF13445.6 EER24519.1 - 7.4e-07 29.1 8.5 7.4e-07 29.1 8.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EER24519.1 - 8e-07 28.9 7.6 8e-07 28.9 7.6 3.3 2 1 1 3 3 2 1 zinc-RING finger domain zf-TRAF_2 PF15965.5 EER24519.1 - 1e-06 29.1 25.0 9.5e-06 26.0 7.9 3.0 2 1 1 3 3 3 2 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 EER24519.1 - 1e-05 25.6 9.4 1e-05 25.6 9.4 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-TRAF PF02176.18 EER24519.1 - 1.3e-05 25.7 35.0 0.0025 18.5 8.1 4.5 2 1 3 5 5 4 4 TRAF-type zinc finger zf-RING_2 PF13639.6 EER24519.1 - 4.1e-05 23.8 10.3 4.1e-05 23.8 10.3 3.7 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.25 EER24519.1 - 9.4e-05 22.2 8.3 9.4e-05 22.2 8.3 3.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER24519.1 - 0.0026 17.6 6.8 0.0026 17.6 6.8 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER24519.1 - 0.014 15.2 10.3 0.014 15.2 10.3 3.8 2 2 1 3 3 2 0 Zinc finger, C3HC4 type (RING finger) Rubredoxin PF00301.20 EER24519.1 - 0.028 14.4 2.0 0.12 12.4 0.1 2.7 2 0 0 2 2 2 0 Rubredoxin HrpB7 PF09486.10 EER24519.1 - 0.091 13.1 2.9 0.15 12.4 2.9 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Sina PF03145.16 EER24519.1 - 0.1 12.5 11.9 0.56 10.1 1.2 3.0 2 1 1 3 3 3 0 Seven in absentia protein family SNARE PF05739.19 EER24520.1 - 3.7e-10 39.6 0.3 6.7e-10 38.8 0.3 1.4 1 0 0 1 1 1 1 SNARE domain FlxA PF14282.6 EER24520.1 - 0.058 13.4 0.3 0.058 13.4 0.3 2.3 2 0 0 2 2 2 0 FlxA-like protein Fzo_mitofusin PF04799.13 EER24520.1 - 0.078 12.5 1.9 0.35 10.4 0.2 2.2 2 0 0 2 2 2 0 fzo-like conserved region FAM184 PF15665.5 EER24520.1 - 0.091 12.5 7.5 1 9.1 0.5 2.1 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF724 PF05266.14 EER24520.1 - 0.12 12.2 2.1 0.15 11.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 EER24520.1 - 0.15 11.3 0.6 0.61 9.4 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Use1 PF09753.9 EER24520.1 - 0.16 11.6 1.9 1 9.0 1.8 2.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 HIP1_clath_bdg PF16515.5 EER24520.1 - 0.18 12.4 3.8 0.83 10.3 0.5 2.4 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1179 PF06678.11 EER24520.1 - 0.29 11.1 2.4 0.58 10.2 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1179) DUF4452 PF14618.6 EER24521.1 - 5.6e-76 254.1 9.8 9.1e-76 253.5 9.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) GerE PF00196.19 EER24521.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family Cyclin_N PF00134.23 EER24522.1 - 6.1e-12 45.4 1.4 4e-11 42.7 0.5 2.1 1 1 1 2 2 2 1 Cyclin, N-terminal domain Mito_carr PF00153.27 EER24523.1 - 1.3e-67 223.8 4.8 9.1e-25 86.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 EER24523.1 - 1.7e-22 77.2 13.2 5e-07 28.8 0.9 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EER24523.1 - 2.4e-20 72.8 11.1 1.6e-12 47.6 1.9 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EER24523.1 - 2.9e-17 61.3 10.4 1.1e-06 27.8 1.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EER24523.1 - 4.5e-17 60.4 12.2 9.9e-05 22.0 0.9 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EER24523.1 - 1.7e-14 53.4 5.5 2.8e-07 30.3 0.4 3.3 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EER24523.1 - 1.8e-08 34.7 0.7 1.7e-05 25.1 0.2 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EER24523.1 - 0.017 15.1 4.8 0.45 10.5 0.4 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand GST_N_2 PF13409.6 EER24524.1 - 1.6e-21 76.3 0.0 4.1e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EER24524.1 - 7.2e-14 51.6 0.0 1.6e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EER24524.1 - 1e-05 25.8 0.0 0.00037 20.8 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EER24524.1 - 0.00087 19.5 0.0 0.002 18.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ThiF PF00899.21 EER24525.1 - 4.6e-111 370.0 0.0 5.9e-74 248.5 0.0 2.3 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EER24525.1 - 1.1e-95 320.4 0.3 1.3e-94 316.9 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EER24525.1 - 4.2e-30 103.7 0.1 1e-29 102.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EER24525.1 - 5.4e-30 104.0 0.0 1.1e-29 102.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EER24525.1 - 2.7e-25 88.4 1.6 1e-24 86.5 1.6 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 EER24525.1 - 0.066 13.7 0.0 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding GCP_N_terminal PF17681.1 EER24526.1 - 7.9e-34 117.7 0.0 1.8e-33 116.5 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EER24526.1 - 1.9e-24 86.7 0.0 2.9e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal MFS_1 PF07690.16 EER24527.1 - 6e-35 120.8 18.3 6e-35 120.8 18.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily PUMA PF15826.5 EER24527.1 - 0.064 13.4 0.1 0.14 12.3 0.1 1.6 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis DUF5527 PF17665.1 EER24527.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5527) ESSS PF10183.9 EER24527.1 - 0.47 10.7 2.4 6.6 7.0 0.0 3.5 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GILT PF03227.16 EER24529.1 - 4.1e-15 55.9 1.4 1.7e-14 54.0 1.5 2.0 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.21 EER24530.1 - 1.6e-61 207.7 0.0 2.2e-61 207.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EER24530.1 - 1.1e-44 152.7 0.0 7.6e-44 149.9 0.0 2.0 1 1 0 1 1 1 1 Hexokinase TFIIA_gamma_C PF02751.14 EER24531.1 - 1.2e-25 89.4 1.8 1.8e-25 88.8 1.8 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EER24531.1 - 1.7e-24 85.5 0.1 2.4e-24 85.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Aldedh PF00171.22 EER24533.1 - 2.3e-131 438.5 0.0 2.6e-131 438.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EER24533.1 - 8.1e-05 21.8 0.3 0.00038 19.6 0.1 2.1 1 1 1 2 2 2 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EER24533.1 - 0.0077 15.7 0.1 0.16 11.4 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) zf-C3HC4_2 PF13923.6 EER24534.1 - 0.68 9.8 5.1 1.6 8.7 2.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_13 PF17977.1 EER24534.1 - 1 9.5 4.4 2.4 8.4 4.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SUR7 PF06687.12 EER24535.1 - 0.13 11.9 1.4 0.19 11.3 1.4 1.2 1 0 0 1 1 1 0 SUR7/PalI family DUF4231 PF14015.6 EER24535.1 - 0.57 10.7 2.3 0.98 9.9 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3784 PF12650.7 EER24535.1 - 3.9 7.7 5.7 14 6.0 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3784) Methyltransf_33 PF10017.9 EER24536.1 - 6.4e-90 301.4 0.1 8.5e-90 301.0 0.1 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EER24536.1 - 2.4e-20 73.2 3.0 8.5e-10 38.6 0.4 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EER24536.1 - 1.4e-05 25.6 0.9 3.8e-05 24.2 0.9 1.8 1 0 0 1 1 1 1 DinB superfamily DUF4164 PF13747.6 EER24537.1 - 0.011 16.0 3.0 0.011 16.0 3.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TPR_2 PF07719.17 EER24537.1 - 0.038 14.1 0.7 0.038 14.1 0.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LRS4 PF10422.9 EER24537.1 - 0.063 12.9 0.4 0.092 12.3 0.4 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 PI_PP_I PF18363.1 EER24537.1 - 0.14 12.4 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 Phosphoinositide phosphatase insertion domain GAS PF13851.6 EER24537.1 - 0.4 10.0 4.5 0.15 11.4 1.9 1.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Nsp1_C PF05064.13 EER24537.1 - 1.3 8.9 4.1 7.6 6.4 0.2 2.5 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF92 PF01940.16 EER24538.1 - 1.6e-80 269.9 1.7 1.2e-78 263.8 1.7 2.1 1 1 0 1 1 1 1 Integral membrane protein DUF92 Radical_SAM PF04055.21 EER24539.1 - 4.8e-10 40.1 0.0 7.2e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EER24539.1 - 5.7e-05 23.4 0.0 0.0001 22.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3878 PF12994.7 EER24539.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3878) Fer4_14 PF13394.6 EER24539.1 - 0.025 14.7 0.1 0.11 12.6 0.1 2.0 2 0 0 2 2 2 0 4Fe-4S single cluster domain RNA_pol PF00940.19 EER24540.1 - 5.3e-187 621.7 0.0 7.3e-187 621.3 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EER24540.1 - 5.6e-91 305.4 0.0 8.3e-91 304.8 0.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.13 EER24541.1 - 1.1e-28 100.6 0.0 3.7e-28 98.9 0.0 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region NIR_SIR PF01077.22 EER24542.1 - 3.2e-52 176.2 0.0 4.1e-46 156.4 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EER24542.1 - 1.5e-31 108.0 0.0 2.7e-14 52.8 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EER24542.1 - 1.2e-29 103.3 0.0 2.4e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EER24542.1 - 2.5e-07 30.7 0.1 5.2e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.11 EER24543.1 - 1.6e-70 236.9 0.3 2e-70 236.6 0.3 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ras PF00071.22 EER24544.1 - 3.6e-49 166.5 0.2 4.4e-49 166.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER24544.1 - 1.6e-25 89.6 0.1 2.4e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER24544.1 - 4.9e-11 42.4 0.2 5.9e-11 42.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EER24544.1 - 2.4e-05 24.0 0.0 4.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EER24544.1 - 0.02 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase TIR_2 PF13676.6 EER24544.1 - 0.068 13.8 0.0 0.1 13.2 0.0 1.3 1 0 0 1 1 1 0 TIR domain Gtr1_RagA PF04670.12 EER24544.1 - 0.093 12.1 0.1 0.11 11.9 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP-synt_C PF00137.21 EER24545.1 - 2.7e-26 91.7 34.0 4.6e-16 58.9 11.4 2.5 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 EER24545.1 - 0.058 12.7 1.1 0.19 11.0 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 MIG-14_Wnt-bd PF06664.12 EER24545.1 - 3.5 6.8 7.2 0.37 10.0 2.2 1.7 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion MoCF_biosynth PF00994.24 EER24546.1 - 6.7e-46 155.5 0.1 1.8e-22 79.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EER24546.1 - 1.4e-37 128.9 1.0 2.2e-37 128.3 1.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EER24546.1 - 1e-15 57.6 0.0 2.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DDHD PF02862.17 EER24547.1 - 3e-18 66.8 0.3 4.5e-16 59.7 0.0 3.3 2 1 0 2 2 2 1 DDHD domain FAD_binding_3 PF01494.19 EER24549.1 - 8.3e-74 248.9 0.0 1e-73 248.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EER24549.1 - 1.5e-36 125.9 0.0 2.5e-36 125.2 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.24 EER24549.1 - 0.00018 21.2 0.1 0.35 10.4 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER24549.1 - 0.0061 15.8 0.0 0.065 12.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER24549.1 - 0.04 14.5 0.0 0.21 12.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER24549.1 - 0.065 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.16 EER24549.1 - 0.094 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 EER24549.1 - 0.11 11.5 0.0 0.78 8.7 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein Elf4 PF07011.11 EER24549.1 - 0.2 11.6 0.0 0.44 10.5 0.0 1.5 1 0 0 1 1 1 0 Early Flowering 4 domain DUF866 PF05907.13 EER24550.1 - 7.1e-30 104.0 0.1 8.1e-30 103.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) RdRP_1 PF00680.20 EER24551.1 - 0.0071 14.9 0.0 0.0071 14.9 0.0 1.0 1 0 0 1 1 1 1 RNA dependent RNA polymerase LSM PF01423.22 EER24552.1 - 1.2e-18 66.6 0.2 1.5e-18 66.2 0.2 1.1 1 0 0 1 1 1 1 LSM domain ADH_N_2 PF16884.5 EER24552.1 - 0.032 14.1 0.0 0.044 13.7 0.0 1.3 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase DASH_Dad1 PF08649.10 EER24553.1 - 9.2e-27 93.0 4.9 1.2e-26 92.6 4.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EER24553.1 - 0.0088 16.0 0.2 0.011 15.7 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad4 WVELL PF14043.6 EER24553.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.5 1 0 0 1 1 1 0 WVELL protein V_ATPase_I PF01496.19 EER24553.1 - 0.064 11.2 0.7 0.07 11.1 0.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Dad2 PF08654.10 EER24553.1 - 0.074 13.5 0.3 0.092 13.2 0.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad2 Ras PF00071.22 EER24554.1 - 5.2e-48 162.7 0.0 6.6e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER24554.1 - 2.2e-20 73.1 0.0 3.5e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER24554.1 - 8.6e-05 22.1 0.0 0.00018 21.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EER24554.1 - 0.014 14.9 0.2 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EER24554.1 - 0.045 13.2 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PAP2 PF01569.21 EER24555.1 - 4e-17 62.2 3.7 1.1e-16 60.8 3.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EER24555.1 - 0.051 13.3 9.1 0.2 11.3 9.1 2.1 1 1 0 1 1 1 0 PAP2 superfamily Peptidase_C48 PF02902.19 EER24556.1 - 3.4e-24 85.9 0.0 6.9e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S30 PF01577.16 EER24556.1 - 0.37 10.4 1.6 0.71 9.4 1.6 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease DUF1664 PF07889.12 EER24558.1 - 1.2e-05 25.3 6.8 0.053 13.6 0.3 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) ADIP PF11559.8 EER24558.1 - 0.0031 17.6 3.9 0.015 15.4 1.4 2.4 1 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF677 PF05055.12 EER24558.1 - 0.005 15.8 1.2 0.0094 14.9 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF677) DUF641 PF04859.12 EER24558.1 - 0.0068 16.7 2.9 0.11 12.8 0.5 2.3 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) DUF3294 PF07957.11 EER24558.1 - 0.01 15.6 0.2 2 8.1 0.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3294) HAUS-augmin3 PF14932.6 EER24558.1 - 0.015 14.9 1.3 0.028 14.0 1.3 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4618 PF15397.6 EER24558.1 - 0.03 13.8 1.7 1.1 8.6 0.6 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) DUF382 PF04037.13 EER24558.1 - 0.11 12.7 0.1 0.32 11.2 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF382) COG5 PF10392.9 EER24558.1 - 0.12 12.6 6.6 1.8 8.8 3.1 2.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Prominin PF05478.11 EER24558.1 - 0.16 9.9 1.5 0.23 9.4 1.5 1.2 1 0 0 1 1 1 0 Prominin Fe-S_assembly PF04384.13 EER24558.1 - 0.16 12.6 1.1 3 8.5 0.1 2.8 3 0 0 3 3 3 0 Iron-sulphur cluster assembly Fez1 PF06818.15 EER24558.1 - 0.22 11.9 3.3 0.75 10.2 3.3 1.8 1 1 0 1 1 1 0 Fez1 DUF4763 PF15960.5 EER24558.1 - 0.36 10.1 5.0 0.72 9.1 4.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) FlaC_arch PF05377.11 EER24558.1 - 0.57 10.6 3.8 9.7 6.7 0.1 3.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 EER24558.1 - 0.6 10.6 5.7 44 4.6 3.4 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF16 PF01519.16 EER24558.1 - 0.7 10.4 4.5 38 4.9 0.3 2.8 1 1 1 2 2 2 0 Protein of unknown function DUF16 LPP PF04728.13 EER24558.1 - 0.72 10.3 3.5 12 6.3 0.5 3.5 2 1 1 3 3 3 0 Lipoprotein leucine-zipper DUF2730 PF10805.8 EER24558.1 - 1.8 8.7 3.6 42 4.3 0.3 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DENN PF02141.21 EER24559.1 - 3.9e-38 131.3 0.0 7.2e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EER24559.1 - 1.1e-05 26.1 0.0 3.7e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 uDENN domain MCC-bdg_PDZ PF10506.9 EER24559.1 - 7.1 6.7 11.1 0.1 12.6 2.7 2.4 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome TMF_TATA_bd PF12325.8 EER24559.1 - 9.7 6.4 20.2 1.8 8.8 6.5 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding zf-HIT PF04438.16 EER24560.1 - 8.2e-10 38.4 10.5 1.4e-09 37.6 10.5 1.4 1 0 0 1 1 1 1 HIT zinc finger adh_short_C2 PF13561.6 EER24561.1 - 7.7e-56 189.3 1.0 9.2e-56 189.0 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER24561.1 - 4.6e-47 160.0 0.8 5.6e-47 159.7 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER24561.1 - 8.3e-10 38.9 0.5 1.9e-09 37.7 0.5 1.5 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EER24561.1 - 0.097 13.4 0.0 0.31 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain RabGAP-TBC PF00566.18 EER24562.1 - 1.2e-43 149.3 0.0 1.4e-41 142.5 0.0 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Pkinase PF00069.25 EER24564.1 - 4.9e-25 88.4 0.0 8.2e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EER24564.1 - 7.2e-11 41.4 7.1 0.14 12.5 0.2 6.7 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 EER24564.1 - 2.3e-10 40.9 9.6 2.7e-06 28.0 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EER24564.1 - 6.2e-08 32.2 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EER24564.1 - 2.5e-05 24.6 0.8 0.59 10.6 0.0 4.6 4 1 1 5 5 4 1 HEAT repeats HEAT_EZ PF13513.6 EER24564.1 - 0.012 16.2 3.2 0.23 12.0 0.2 4.2 4 0 0 4 4 4 0 HEAT-like repeat Kinase-like PF14531.6 EER24564.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Tti2 PF10521.9 EER24564.1 - 0.043 13.4 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Tti2 family N_formyltrans_C PF18216.1 EER24564.1 - 0.059 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Ge1_WD40 PF16529.5 EER24564.1 - 0.18 10.8 0.0 0.45 9.4 0.0 1.6 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RTP1_C1 PF10363.9 EER24564.1 - 0.2 11.8 0.1 17 5.6 0.0 2.7 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-C2H2 PF00096.26 EER24565.1 - 2.6e-10 40.2 21.3 0.00061 20.1 3.4 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER24565.1 - 1.6e-07 31.6 20.3 0.021 15.6 2.1 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger CpXC PF14353.6 EER24565.1 - 0.0029 17.6 4.0 0.037 14.1 0.5 2.4 1 1 1 2 2 2 1 CpXC protein zf-C2H2_3 PF13878.6 EER24565.1 - 0.0049 16.7 2.9 0.035 13.9 1.4 2.7 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO zf-H2C2_2 PF13465.6 EER24565.1 - 0.015 15.7 23.8 0.89 10.1 0.4 4.0 4 0 0 4 4 3 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 EER24565.1 - 0.2 11.6 5.6 2.7 8.0 0.5 3.0 3 0 0 3 3 3 0 zinc-ribbon domain PRP21_like_P PF12230.8 EER24565.1 - 0.44 10.4 7.1 0.51 10.2 2.8 2.2 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_2 PF12756.7 EER24565.1 - 0.5 10.7 11.4 4.2 7.8 1.9 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-ribbon_3 PF13248.6 EER24565.1 - 1.4 8.4 8.1 6.1 6.4 1.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EER24565.1 - 1.6 8.7 11.3 1.3 9.0 2.0 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-C2H2_11 PF16622.5 EER24565.1 - 1.9 8.3 16.7 0.23 11.2 2.1 3.5 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-BED PF02892.15 EER24565.1 - 2.2 8.4 10.8 1.3 9.1 1.8 3.0 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 EER24565.1 - 4 7.3 9.8 5.2 6.9 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EER24565.1 - 5.9 7.0 15.3 0.25 11.4 0.3 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger TFIIS_C PF01096.18 EER24565.1 - 9.9 6.1 9.4 12 5.8 0.1 3.0 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) NUDIX PF00293.28 EER24566.1 - 3.9e-28 98.1 0.0 5.8e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain MatE PF01554.18 EER24567.1 - 2.6e-55 186.5 28.1 3e-35 121.3 10.4 2.2 2 0 0 2 2 2 2 MatE DnaJ PF00226.31 EER24568.1 - 1.9e-13 50.3 1.0 1.1e-12 47.9 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain VIR_N PF15912.5 EER24568.1 - 1.3 8.6 4.7 1.5 8.4 4.7 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DEAD PF00270.29 EER24569.1 - 5.9e-47 159.7 0.1 1.3e-46 158.6 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER24569.1 - 3.1e-24 85.4 0.1 2.1e-23 82.8 0.0 2.4 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EER24569.1 - 8.3e-22 77.2 0.0 2.9e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EER24569.1 - 6e-08 32.9 0.0 1.8e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EER24569.1 - 0.11 12.7 0.0 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 Helicase C-terminal domain AA_permease PF00324.21 EER24570.1 - 6.6e-124 414.1 37.9 8.2e-124 413.8 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER24570.1 - 1.6e-38 132.7 43.7 1.8e-38 132.5 43.7 1.0 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 EER24571.1 - 0.00022 21.3 10.6 0.00044 20.3 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IHO1 PF15771.5 EER24571.1 - 0.39 9.4 5.4 0.77 8.5 0.2 2.1 2 0 0 2 2 2 0 Interactor of HORMAD1 protein 1 DEAD PF00270.29 EER24572.1 - 2.8e-47 160.8 0.0 6.1e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER24572.1 - 1.7e-23 83.1 0.1 1.2e-22 80.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EER24572.1 - 2.4e-21 75.7 1.7 1.1e-20 73.6 1.7 2.3 1 0 0 1 1 1 1 DBP10CT (NUC160) domain IMD PF08397.11 EER24572.1 - 6.9 6.0 9.4 14 5.0 9.4 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain RPA_C PF08784.11 EER24573.1 - 1e-15 58.3 0.2 3.1e-15 56.7 0.0 1.9 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EER24573.1 - 2.1e-06 27.6 0.1 5.9e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PAPS_reduct PF01507.19 EER24574.1 - 5.1e-28 98.3 0.0 4.5e-26 91.9 0.0 2.4 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.22 EER24575.1 - 4.7e-20 71.2 0.2 1.6e-10 40.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.20 EER24576.1 - 4.9e-65 219.2 0.0 6.8e-65 218.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EER24576.1 - 3.9e-34 117.9 2.0 8.5e-34 116.8 2.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EER24576.1 - 2e-22 79.9 0.0 9.7e-22 77.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain MOR2-PAG1_N PF14222.6 EER24577.1 - 5.2e-215 715.6 0.0 8.2e-215 714.9 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EER24577.1 - 7.8e-89 297.9 2.1 1.5e-88 296.9 0.3 2.4 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EER24577.1 - 1.4e-37 129.0 11.2 3.9e-18 64.6 0.0 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region Cu_amine_oxid PF01179.20 EER24578.1 - 3.3e-165 550.0 0.2 4e-165 549.7 0.2 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EER24578.1 - 3.4e-05 24.2 0.1 7.9e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EER24578.1 - 0.015 15.5 0.1 0.033 14.4 0.1 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain PhoD PF09423.10 EER24579.1 - 2.8e-105 352.2 0.1 3.4e-105 351.9 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EER24579.1 - 4e-32 110.6 0.0 9.9e-32 109.3 0.0 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EER24579.1 - 0.00019 22.0 0.5 0.00052 20.5 0.1 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain HhH-GPD PF00730.25 EER24581.1 - 1.6e-15 57.5 0.0 4.4e-15 56.1 0.0 1.8 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EER24581.1 - 2.6e-08 33.3 0.0 8.5e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif UQ_con PF00179.26 EER24582.1 - 1.8e-40 137.9 0.0 1.9e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER24582.1 - 0.0019 17.9 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 EER24582.1 - 0.044 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EER24582.1 - 0.073 13.4 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 RWD domain PRCC PF10253.9 EER24583.1 - 0.55 11.0 16.3 0.87 10.3 16.3 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting HATPase_c PF02518.26 EER24584.1 - 5e-26 91.4 0.0 1.5e-25 89.9 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EER24584.1 - 4.5e-24 84.8 0.3 9.3e-24 83.8 0.3 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EER24584.1 - 3.5e-18 65.4 0.3 1e-17 63.9 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EER24584.1 - 4.8e-18 65.3 0.0 7.5e-14 51.9 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.10 EER24584.1 - 2.4e-17 63.2 0.0 1.6e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 EER24584.1 - 1.6e-15 57.0 0.0 1.6e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 EER24584.1 - 0.0004 20.3 0.0 0.26 11.3 0.0 2.7 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 EER24584.1 - 0.0007 19.8 0.1 0.0015 18.8 0.1 1.6 1 0 0 1 1 1 1 PAS fold PAS_10 PF13596.6 EER24584.1 - 0.00089 19.8 0.0 0.0041 17.7 0.0 2.1 2 0 0 2 2 2 1 PAS domain AAA_11 PF13086.6 EER24585.1 - 6.5e-64 216.2 0.3 1.9e-63 214.7 0.4 1.7 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EER24585.1 - 2.6e-56 190.4 0.0 4.5e-56 189.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EER24585.1 - 1.4e-11 44.5 0.0 6.2e-07 29.3 0.0 2.9 1 1 2 3 3 3 2 AAA domain AAA_19 PF13245.6 EER24585.1 - 1.1e-08 35.5 0.0 2.9e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EER24585.1 - 1.5e-07 31.4 0.0 0.23 11.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EER24585.1 - 1.3e-06 28.5 0.0 3.1e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EER24585.1 - 3.6e-06 26.5 0.7 1.4e-05 24.5 0.7 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EER24585.1 - 4e-06 26.6 0.1 0.00095 18.8 0.0 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EER24585.1 - 3.1e-05 24.3 0.1 0.00036 20.8 0.1 2.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EER24585.1 - 0.00029 20.7 0.0 0.2 11.5 0.0 2.8 3 0 0 3 3 3 1 Helicase AAA_16 PF13191.6 EER24585.1 - 0.00039 20.9 0.1 0.0011 19.4 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 EER24585.1 - 0.00099 18.6 0.0 0.15 11.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein T2SSE PF00437.20 EER24585.1 - 0.0021 17.2 0.0 0.0048 16.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C PF13361.6 EER24585.1 - 0.0054 16.1 0.0 1.5 8.1 0.0 2.8 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 EER24585.1 - 0.0063 16.5 0.0 0.099 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Flavi_DEAD PF07652.14 EER24585.1 - 0.0069 16.4 0.0 0.023 14.7 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA_23 PF13476.6 EER24585.1 - 0.0076 16.8 0.1 2.2 8.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EER24585.1 - 0.0091 16.4 0.1 0.044 14.2 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 EER24585.1 - 0.013 15.3 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain IstB_IS21 PF01695.17 EER24585.1 - 0.041 13.6 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 EER24585.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EER24585.1 - 0.048 13.2 0.1 0.53 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 EER24585.1 - 0.084 13.0 0.3 0.27 11.4 0.2 1.8 1 1 0 1 1 1 0 Shikimate kinase 4HB_MCP_1 PF12729.7 EER24585.1 - 0.091 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction TrwB_AAD_bind PF10412.9 EER24585.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.21 EER24585.1 - 0.12 11.7 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIG-F PF06699.11 EER24588.1 - 7.4e-68 228.3 1.9 9.2e-68 228.0 1.9 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F ABC2_membrane PF01061.24 EER24588.1 - 0.011 15.2 1.5 0.42 10.0 0.9 2.3 2 0 0 2 2 2 0 ABC-2 type transporter Gly-zipper_Omp PF13488.6 EER24588.1 - 3.3 7.8 11.4 0.78 9.8 2.4 2.6 3 0 0 3 3 3 0 Glycine zipper ATPase_gene1 PF09527.10 EER24588.1 - 5.9 7.1 13.1 4.9 7.4 0.2 3.3 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter ADH_N PF08240.12 EER24590.1 - 7.1e-26 90.2 2.1 1.9e-25 88.8 2.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER24590.1 - 3.3e-18 65.9 0.2 7e-18 64.9 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EER24590.1 - 0.0021 17.4 0.7 0.0038 16.6 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EER24590.1 - 0.0021 18.3 0.1 0.0039 17.4 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N_2 PF13602.6 EER24590.1 - 0.019 16.0 0.0 0.044 14.8 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase zf-Tim10_DDP PF02953.15 EER24591.1 - 1.8e-18 65.9 5.3 2.6e-18 65.4 5.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EER24591.1 - 0.005 16.5 2.4 0.81 9.4 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF842) RhoGAP PF00620.27 EER24592.1 - 4.9e-38 130.3 0.0 9.7e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF2284 PF10050.9 EER24593.1 - 7.5e-05 22.5 87.7 1.4 8.6 1.9 9.6 9 1 1 10 10 10 9 Predicted metal-binding protein (DUF2284) PS_Dcarbxylase PF02666.15 EER24594.1 - 6e-31 107.6 0.0 7.7e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.8 EER24594.1 - 2.9e-09 37.0 0.0 4.7e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Peptidase_S10 PF00450.22 EER24595.1 - 4.5e-80 270.1 7.1 7.1e-80 269.5 7.1 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase GDPD PF03009.17 EER24596.1 - 1.1e-28 100.6 0.0 1.7e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EER24596.1 - 0.00028 21.2 0.3 0.0006 20.2 0.3 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family LIM PF00412.22 EER24597.1 - 1.4e-16 60.5 19.7 5.2e-11 42.6 2.9 3.2 3 0 0 3 3 3 2 LIM domain zf_C2HC_14 PF18574.1 EER24597.1 - 5.8 6.8 7.0 0.82 9.5 1.9 2.1 2 0 0 2 2 2 0 C2HC Zing finger domain NAD_binding_5 PF07994.12 EER24598.1 - 7.1e-145 482.4 0.0 8.7e-145 482.1 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EER24598.1 - 2.1e-44 150.2 0.4 4.3e-44 149.2 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase APH PF01636.23 EER24599.1 - 9.1e-08 32.3 0.0 4.3e-07 30.1 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Amidase PF01425.21 EER24600.1 - 1.4e-77 261.6 0.8 5.2e-74 249.8 0.6 2.1 2 0 0 2 2 2 2 Amidase Glyco_hydro_72 PF03198.14 EER24601.1 - 3.5e-134 447.0 1.5 4.2e-134 446.8 1.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EER24601.1 - 3.8e-07 29.8 0.6 2.8e-06 27.0 0.6 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FCH PF00611.23 EER24602.1 - 1.7e-23 82.7 2.4 2.8e-23 82.0 0.2 2.5 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 EER24602.1 - 1.4e-15 56.9 4.5 2.4e-15 56.2 4.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EER24602.1 - 0.004 17.4 3.7 0.0072 16.6 3.7 1.4 1 0 0 1 1 1 1 C1 domain SH3_1 PF00018.28 EER24602.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 SH3 domain FYVE PF01363.21 EER24602.1 - 0.16 12.1 3.4 0.38 10.9 3.4 1.6 1 0 0 1 1 1 0 FYVE zinc finger DEAD PF00270.29 EER24603.1 - 3.2e-36 124.8 0.5 2.1e-35 122.1 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER24603.1 - 1.5e-23 83.2 0.2 5e-23 81.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER24603.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EER24603.1 - 0.01 15.2 0.2 0.026 13.9 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF3217 PF11506.8 EER24603.1 - 0.097 12.6 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) N1221 PF07923.13 EER24603.1 - 0.22 10.7 0.6 0.36 10.0 0.6 1.2 1 0 0 1 1 1 0 N1221-like protein Arginase PF00491.21 EER24604.1 - 1.6e-83 280.5 0.3 1.9e-83 280.2 0.3 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EER24604.1 - 0.059 13.6 0.1 0.09 13.0 0.1 1.2 1 0 0 1 1 1 0 UPF0489 domain GAF_2 PF13185.6 EER24605.1 - 1e-11 45.3 0.0 1.6e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EER24605.1 - 4.6e-08 33.8 0.0 5.7e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EER24605.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 GAF domain Pkinase PF00069.25 EER24606.1 - 3.8e-10 39.6 0.0 6.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24606.1 - 1.6e-08 34.2 0.0 1.3e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EER24606.1 - 8.8e-07 29.1 0.5 0.0011 18.9 0.4 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER24606.1 - 0.0095 15.5 0.1 1.9 8.0 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Kdo PF06293.14 EER24606.1 - 0.047 13.0 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EER24607.1 - 2.5e-125 418.5 0.0 3.1e-125 418.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase MauJ PF17419.2 EER24607.1 - 0.0011 18.5 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Methylamine utilization protein MauJ NAD_kinase PF01513.21 EER24608.1 - 2.5e-77 260.0 0.0 3.4e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Pro-kuma_activ PF09286.11 EER24609.1 - 5.5e-28 98.0 0.0 1.7e-27 96.4 0.0 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EER24609.1 - 2.3e-08 33.7 1.1 1.3e-06 28.0 0.1 2.1 2 0 0 2 2 2 2 Subtilase family HOOK PF05622.12 EER24610.1 - 1.5e-07 30.0 15.6 2e-07 29.6 15.6 1.3 1 0 0 1 1 1 1 HOOK protein ERM PF00769.19 EER24610.1 - 0.0066 16.3 49.5 0.0066 16.3 49.5 2.1 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Choline_kinase PF01633.20 EER24610.1 - 0.014 15.0 5.3 0.014 15.0 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Otopetrin PF03189.13 EER24610.1 - 0.019 13.8 0.0 0.037 12.8 0.0 1.5 1 1 0 1 1 1 0 Otopetrin APH PF01636.23 EER24610.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.1 2 0 0 2 2 1 0 Phosphotransferase enzyme family eIF3_subunit PF08597.10 EER24610.1 - 0.7 9.8 37.3 1.4 8.7 37.3 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit LCD1 PF09798.9 EER24610.1 - 1.2 7.6 14.7 1.7 7.1 14.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein ALMT PF11744.8 EER24610.1 - 1.4 7.7 16.6 2.7 6.7 16.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 EER24610.1 - 2.1 6.2 15.9 3.1 5.6 15.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sin_N PF04801.13 EER24610.1 - 3.2 6.8 19.0 5.5 6.1 19.0 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region RRN3 PF05327.11 EER24610.1 - 4.3 5.8 12.5 7.6 4.9 12.5 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Apt1 PF10351.9 EER24610.1 - 7.6 5.3 14.1 0.5 9.2 6.8 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 EER24610.1 - 9.8 6.0 32.6 2.8 7.8 25.4 2.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal E1-E2_ATPase PF00122.20 EER24612.1 - 1.1e-40 139.1 13.5 1.4e-32 112.7 0.0 3.7 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EER24612.1 - 9e-25 87.4 4.8 9e-25 87.4 4.8 2.6 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EER24612.1 - 8.2e-17 62.2 0.2 1.9e-13 51.2 0.1 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EER24612.1 - 1.4e-16 59.9 0.9 3.1e-16 58.8 0.2 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EER24612.1 - 8.7e-13 48.2 0.0 1.6e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EER24612.1 - 2.6e-06 27.4 2.3 2.1e-05 24.4 1.7 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2014 PF09427.10 EER24613.1 - 1.2e-104 349.4 1.1 1.6e-104 348.9 1.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EER24613.1 - 5.4e-18 64.7 1.3 2.1e-17 62.8 0.8 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 EER24613.1 - 0.012 16.0 3.8 0.012 16.0 3.8 1.9 2 0 0 2 2 2 0 Cell division protein ZapB bZIP_1 PF00170.21 EER24613.1 - 0.05 13.7 6.2 0.036 14.2 3.7 2.1 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 EER24613.1 - 0.1 12.7 8.4 0.031 14.4 3.7 2.2 2 0 0 2 2 2 0 Basic region leucine zipper TSC22 PF01166.18 EER24613.1 - 0.43 10.9 2.7 1 9.8 1.7 2.0 2 0 0 2 2 2 0 TSC-22/dip/bun family DIT1_PvcA PF05141.12 EER24614.1 - 2.8e-93 312.4 0.0 3.6e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 EER24614.1 - 3.6e-25 89.3 0.1 8.6e-25 88.0 0.1 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.19 EER24615.1 - 1.3e-53 182.5 0.0 2e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EER24615.1 - 0.0011 18.4 1.1 0.0015 17.9 0.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EER24615.1 - 0.0063 15.3 1.3 0.0099 14.6 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EER24615.1 - 0.0066 16.1 1.0 0.045 13.3 0.3 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER24615.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER24615.1 - 0.0092 16.2 0.8 0.028 14.6 0.8 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EER24615.1 - 0.011 15.0 0.4 0.2 10.9 0.3 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER24615.1 - 0.043 14.4 0.7 0.57 10.8 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EER24615.1 - 0.098 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EER24615.1 - 0.18 10.8 1.2 0.3 10.1 1.2 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short_C2 PF13561.6 EER24616.1 - 3.4e-35 121.7 0.0 9.4e-35 120.3 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER24616.1 - 8.1e-31 107.0 0.0 2.1e-30 105.6 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER24616.1 - 7.5e-08 32.5 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 KR domain CoA_transf_3 PF02515.17 EER24617.1 - 1.9e-36 126.0 0.0 5.5e-36 124.4 0.0 1.7 2 0 0 2 2 2 1 CoA-transferase family III SAT PF16073.5 EER24618.1 - 1.8e-35 122.8 1.3 2.2e-35 122.5 1.3 1.0 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis p450 PF00067.22 EER24619.1 - 2e-67 227.9 0.0 2.4e-67 227.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EER24620.1 - 7.8e-23 81.0 51.7 4.9e-22 78.3 38.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.22 EER24621.1 - 6.5e-41 139.9 0.0 8.3e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3042 PF11240.8 EER24621.1 - 0.096 12.7 0.9 2.1 8.5 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Peptidase_U4 PF03419.13 EER24622.1 - 0.0067 15.8 1.6 0.011 15.1 1.6 1.3 1 0 0 1 1 1 1 Sporulation factor SpoIIGA F-box_4 PF15966.5 EER24624.1 - 0.00013 21.9 0.2 0.00085 19.2 0.0 2.2 2 0 0 2 2 2 1 F-box F-box PF00646.33 EER24624.1 - 0.015 15.2 0.7 0.075 12.9 0.0 2.3 2 0 0 2 2 2 0 F-box domain Peroxin-13_N PF04088.13 EER24624.1 - 0.096 13.0 0.1 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region F-box-like PF12937.7 EER24624.1 - 0.27 11.1 2.0 1.4 8.9 0.1 2.9 3 0 0 3 3 3 0 F-box-like Mito_carr PF00153.27 EER24626.1 - 2.2e-51 171.7 0.1 3.5e-17 62.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Anp1 PF03452.14 EER24627.1 - 1.9e-109 365.1 0.0 2.6e-109 364.7 0.0 1.2 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EER24627.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Zip PF02535.22 EER24628.1 - 1.2e-61 208.8 3.0 5.1e-61 206.7 3.0 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Nop16 PF09420.10 EER24629.1 - 8.8e-72 241.5 9.9 1e-71 241.3 9.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Pex24p PF06398.11 EER24631.1 - 4.2e-91 305.7 0.0 5.2e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EER24631.1 - 0.0014 17.1 6.5 0.045 12.1 1.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.10 EER24631.1 - 0.22 11.3 1.0 0.56 9.9 0.2 2.0 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Pkinase PF00069.25 EER24632.1 - 9.1e-54 182.6 0.0 1.3e-53 182.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24632.1 - 3.2e-20 72.5 0.0 5e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER24632.1 - 0.014 15.3 0.0 0.072 13.0 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family COPIIcoated_ERV PF07970.12 EER24633.1 - 1.2e-35 123.4 0.0 1.9e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EER24633.1 - 5.2e-23 81.2 0.0 8.7e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ADH_N PF08240.12 EER24634.1 - 3.2e-21 75.2 2.7 5.7e-21 74.5 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER24634.1 - 7.2e-13 48.6 0.0 1.3e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EER24634.1 - 0.0098 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.19 EER24634.1 - 0.069 13.9 0.2 0.66 10.7 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain Fer4_4 PF12800.7 EER24634.1 - 0.24 12.0 2.9 0.55 10.9 2.9 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain RBR PF17208.3 EER24635.1 - 0.45 11.3 9.0 2.8 8.7 9.0 2.4 1 0 0 1 1 1 0 RNA binding Region DUF3367 PF11847.8 EER24635.1 - 1.6 6.5 4.6 3.1 5.6 4.6 1.4 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Pedibin PF08182.11 EER24635.1 - 9.9 6.1 11.0 0.36 10.6 0.6 3.5 4 0 0 4 4 4 0 Pedibin/Hym-346 family Maf1 PF09174.10 EER24636.1 - 5e-65 218.9 0.0 6.5e-65 218.5 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 EER24637.1 - 1.3e-51 174.2 1.8 1.6e-51 174.0 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EER24637.1 - 0.043 14.6 0.0 0.089 13.5 0.0 1.6 1 0 0 1 1 1 0 Pullulanase N1-terminal domain Fungal_trans_2 PF11951.8 EER24637.1 - 0.08 11.7 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 EER24638.1 - 6.2e-10 38.8 0.0 9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.14 EER24639.1 - 1.5e-09 37.5 0.0 4.1e-07 29.6 0.0 2.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EER24639.1 - 3.6e-07 29.8 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EER24639.1 - 1.3e-06 28.5 0.2 0.013 15.4 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER24639.1 - 0.002 17.8 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EER24639.1 - 0.002 17.8 0.0 0.47 10.0 0.0 2.8 3 0 0 3 3 3 2 RIO1 family Pkinase_fungal PF17667.1 EER24639.1 - 0.038 12.8 0.0 0.052 12.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EER24639.1 - 0.054 12.8 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase STE2 PF02116.15 EER24640.1 - 9.4e-96 320.4 21.1 1.1e-95 320.2 21.1 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.13 EER24641.1 - 3.8e-37 126.8 0.0 6.2e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EER24641.1 - 5.1e-21 74.4 0.5 1.2e-20 73.1 0.0 1.9 3 0 0 3 3 3 1 Vps23 core domain UQ_con PF00179.26 EER24641.1 - 0.0069 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ADIP PF11559.8 EER24641.1 - 0.041 14.0 1.4 0.067 13.3 1.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IDO PF01231.18 EER24642.1 - 3.2e-159 530.4 0.0 3.7e-159 530.2 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.19 EER24643.1 - 2.7e-94 316.2 0.0 3.3e-94 315.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EER24643.1 - 2.4e-07 30.4 0.0 3.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EER24643.1 - 1.3e-05 24.7 0.1 4.2e-05 23.0 0.1 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EER24643.1 - 0.0031 16.3 0.0 0.0048 15.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 EER24643.1 - 0.099 11.2 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 EER24643.1 - 0.11 12.5 0.0 0.71 9.9 0.0 2.4 4 0 0 4 4 4 0 B12 binding domain GST_N PF02798.20 EER24644.1 - 4.8e-17 62.1 0.0 1.1e-16 61.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EER24644.1 - 1.4e-16 60.7 0.0 2.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EER24644.1 - 5.4e-13 49.0 0.1 8e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EER24644.1 - 1.5e-10 41.2 0.0 2.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EER24644.1 - 1.3e-05 25.3 0.1 3.6e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EER24644.1 - 0.0023 17.9 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain APH PF01636.23 EER24645.1 - 0.00077 19.5 0.1 0.0023 17.9 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Sugar_tr PF00083.24 EER24646.1 - 7.1e-84 282.2 20.5 8.3e-84 282.0 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER24646.1 - 1.7e-12 46.9 32.4 2e-10 40.2 10.4 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EER24646.1 - 0.00022 20.2 5.4 0.00022 20.2 5.4 2.3 2 0 0 2 2 2 1 MFS_1 like family BAR PF03114.18 EER24647.1 - 1.3e-65 221.4 5.3 1.7e-65 221.0 5.3 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EER24647.1 - 2.4e-13 49.5 0.1 4.6e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER24647.1 - 1.6e-07 31.1 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EER24647.1 - 6.9e-07 28.9 0.2 2.3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 EER24647.1 - 0.027 14.0 5.6 0.54 9.8 3.1 2.2 2 0 0 2 2 2 0 Vps5 C terminal like BRE1 PF08647.11 EER24647.1 - 0.22 11.6 9.4 0.47 10.6 0.2 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase BAR_3 PF16746.5 EER24647.1 - 0.35 10.5 8.1 0.67 9.6 8.1 1.6 1 1 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 EER24647.1 - 1.9 7.7 7.8 7.4 5.7 0.2 2.1 1 1 1 2 2 2 0 TMPIT-like protein CorA PF01544.18 EER24647.1 - 4.8 6.4 10.5 16 4.7 6.1 2.4 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein COesterase PF00135.28 EER24648.1 - 5.2e-85 286.3 0.0 7.2e-85 285.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EER24648.1 - 0.0013 18.7 0.0 0.0052 16.7 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold C4 PF01413.19 EER24648.1 - 0.036 14.4 0.1 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 C-terminal tandem repeated domain in type 4 procollagen Peptidase_S9 PF00326.21 EER24648.1 - 0.1 12.1 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Kdo PF06293.14 EER24649.1 - 0.0002 20.8 0.6 0.00039 19.8 0.6 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER24649.1 - 0.0011 19.0 1.9 0.019 14.9 0.5 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EER24649.1 - 0.086 12.4 0.0 0.7 9.5 0.0 2.1 2 0 0 2 2 2 0 RIO1 family AlaDh_PNT_N PF05222.15 EER24650.1 - 4.9e-25 88.4 0.0 7.5e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EER24650.1 - 0.089 12.1 0.4 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F-box PF00646.33 EER24651.1 - 5.8e-06 26.0 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EER24651.1 - 0.0021 17.9 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like tRNA-synt_1c PF00749.21 EER24652.1 - 1e-99 333.4 0.0 1.3e-99 333.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EER24652.1 - 2e-32 112.5 0.0 5.6e-31 107.7 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain E1-E2_ATPase PF00122.20 EER24653.1 - 6.1e-18 65.0 0.0 1.4e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EER24653.1 - 2.6e-12 47.5 5.6 6.1e-07 29.9 1.8 3.6 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EER24653.1 - 0.0088 15.8 0.1 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EER24653.1 - 0.013 15.5 0.3 0.063 13.4 0.0 2.2 3 0 0 3 3 3 0 Cation transport ATPase (P-type) S6PP PF05116.13 EER24653.1 - 0.048 13.2 0.4 1.3 8.5 0.0 2.8 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase FYVE PF01363.21 EER24654.1 - 8.7e-23 80.2 26.8 2.9e-17 62.6 4.8 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EER24654.1 - 1e-16 60.4 0.7 2.5e-16 59.1 0.7 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 EER24654.1 - 0.005 17.0 6.5 0.005 17.0 6.5 3.9 4 1 1 5 5 5 1 AN1-like Zinc finger zf-Di19 PF05605.12 EER24654.1 - 0.026 14.8 0.1 0.026 14.8 0.1 3.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding C6_DPF PF10170.9 EER24654.1 - 0.3 11.5 5.3 0.23 11.9 0.6 2.7 2 0 0 2 2 2 0 Cysteine-rich domain zf-C2H2_4 PF13894.6 EER24654.1 - 0.9 10.5 0.0 0.9 10.5 0.0 5.4 5 1 0 5 5 5 0 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 EER24654.1 - 1 9.4 6.9 5.2 7.1 0.5 3.7 3 0 0 3 3 3 0 Ubiquitin-binding zinc-finger zf-TFIIB PF13453.6 EER24654.1 - 1.8 8.0 7.9 8 5.9 2.0 3.4 3 0 0 3 3 3 0 Transcription factor zinc-finger HypA PF01155.19 EER24654.1 - 4.1 7.5 15.4 0.18 11.8 0.3 3.6 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Fer4_21 PF14697.6 EER24654.1 - 9.1 6.5 11.1 0.51 10.5 4.7 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain PKD_channel PF08016.12 EER24655.1 - 2.2e-07 29.9 15.9 2.4e-06 26.5 15.9 2.1 1 1 0 1 1 1 1 Polycystin cation channel EIF_2_alpha PF07541.12 EER24656.1 - 2.8e-38 130.6 0.0 6.1e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EER24656.1 - 7.7e-14 51.8 0.6 1.6e-13 50.8 0.6 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.20 EER24657.1 - 8.1e-63 212.4 4.8 1.1e-62 212.1 3.6 1.6 1 1 1 2 2 2 1 Sulfate permease family STAS PF01740.21 EER24657.1 - 8.4e-17 60.9 0.0 1.6e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EER24657.1 - 0.043 14.2 0.0 0.094 13.1 0.0 1.6 1 0 0 1 1 1 0 STAS domain CENP-L PF13092.6 EER24658.1 - 3.9e-48 163.7 0.0 5.5e-48 163.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Acetyltransf_1 PF00583.25 EER24659.1 - 2.5e-07 31.0 0.0 4.2e-07 30.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER24659.1 - 6.5e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER24659.1 - 0.00018 21.8 0.0 0.00026 21.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Toxin-JAB1 PF15659.6 EER24659.1 - 0.075 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 JAB-like toxin 1 DUF1176 PF06674.11 EER24659.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) Fungal_lectin_2 PF18647.1 EER24660.1 - 0.00015 22.2 9.7 0.23 11.9 0.1 4.2 3 1 0 3 3 3 2 Alpha-galactosyl-binding fungal lectin Caleosin PF05042.13 EER24660.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Caleosin related protein DUF3292 PF11696.8 EER24660.1 - 0.53 8.6 2.3 0.77 8.1 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Peptidase_M35 PF02102.15 EER24661.1 - 0.0073 15.2 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family CT_A_B PF02626.15 EER24661.1 - 0.088 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain A and B Palm_thioest PF02089.15 EER24662.1 - 1e-81 274.4 0.0 1.2e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EER24662.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PhoLip_ATPase_N PF16209.5 EER24662.1 - 0.11 12.2 1.1 8.5 6.2 0.2 2.4 2 0 0 2 2 2 0 Phospholipid-translocating ATPase N-terminal TOH_N PF12549.8 EER24663.1 - 0.24 11.3 1.8 14 5.7 0.2 2.9 2 0 0 2 2 2 0 Tyrosine hydroxylase N terminal DUF3328 PF11807.8 EER24665.1 - 4.2e-34 118.2 0.1 5e-22 78.8 2.7 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) FidL_like PF15941.5 EER24665.1 - 0.034 14.6 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 FidL-like putative membrane protein zf-C2H2 PF00096.26 EER24666.1 - 0.3 11.6 6.3 2.9 8.5 0.2 3.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.10 EER24667.1 - 2.1e-66 224.2 0.0 7.9e-66 222.3 0.0 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 DUF3618 PF12277.8 EER24667.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) F-box-like PF12937.7 EER24668.1 - 7e-06 25.8 0.8 1.4e-05 24.9 0.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER24668.1 - 0.015 15.2 1.3 0.057 13.3 0.3 2.5 2 0 0 2 2 2 0 F-box domain Methyltransf_16 PF10294.9 EER24669.1 - 1.3e-11 44.5 0.0 2.7e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase DUF3403 PF11883.8 EER24669.1 - 0.0058 16.7 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3403) NNMT_PNMT_TEMT PF01234.17 EER24669.1 - 0.025 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Aminotran_1_2 PF00155.21 EER24672.1 - 3.7e-39 134.9 0.0 4.9e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EER24672.1 - 0.25 10.0 0.0 0.4 9.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III GLTP PF08718.11 EER24673.1 - 2.6e-46 157.6 0.0 3.3e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH_4 PF15404.6 EER24674.1 - 9.9e-54 181.9 3.3 6.4e-53 179.3 0.1 3.5 4 1 0 4 4 4 1 Pleckstrin homology domain Spo7_2_N PF15407.6 EER24674.1 - 6.5e-26 89.8 2.2 6.5e-26 89.8 2.2 2.1 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 EER24674.1 - 3e-05 24.5 2.8 2 9.0 0.0 5.7 4 1 0 4 4 4 1 PH domain mRNA_stabil PF13929.6 EER24674.1 - 0.0043 16.1 0.8 0.0096 14.9 0.1 1.8 2 0 0 2 2 2 1 mRNA stabilisation PH_9 PF15410.6 EER24674.1 - 0.029 14.8 0.0 2.5 8.5 0.0 3.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.6 EER24674.1 - 0.056 13.7 0.1 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_S24 PF00717.23 EER24675.1 - 1.3e-05 25.1 0.0 4.6e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EER24675.1 - 0.0028 17.5 0.0 0.022 14.5 0.0 2.2 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Macro PF01661.21 EER24676.1 - 5.3e-39 132.9 0.0 8.1e-39 132.3 0.0 1.3 1 0 0 1 1 1 1 Macro domain VIT PF08487.10 EER24677.1 - 5.5e-37 126.4 0.3 1e-36 125.5 0.3 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EER24677.1 - 4.2e-30 104.7 0.0 1.2e-29 103.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.6 EER24677.1 - 1.2e-17 63.6 0.0 3.8e-17 61.9 0.0 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EER24677.1 - 1.7e-08 34.9 0.0 3.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EER24677.1 - 8.5e-07 29.6 0.0 1.8e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EER24677.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein GATA PF00320.27 EER24678.1 - 1.1e-15 57.0 4.2 1.7e-15 56.3 4.2 1.4 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 EER24678.1 - 0.12 12.7 1.6 0.23 11.7 1.6 1.4 1 0 0 1 1 1 0 zinc-ribbon DUF1155 PF06633.11 EER24678.1 - 0.26 10.8 1.7 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) GCS PF03074.16 EER24679.1 - 3.6e-176 585.9 0.0 4.3e-176 585.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase p450 PF00067.22 EER24680.1 - 3.1e-58 197.6 0.0 7.4e-58 196.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EER24681.1 - 2.5e-16 59.9 0.0 3.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER24681.1 - 1.2e-10 42.0 0.0 2.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER24681.1 - 1.4e-08 34.6 0.0 1.1e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER24681.1 - 8.4e-07 29.6 0.0 1.6e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER24681.1 - 1.2e-06 29.1 0.0 6.2e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER24681.1 - 0.0016 18.0 0.0 0.036 13.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.19 EER24681.1 - 0.0029 17.7 0.0 0.0091 16.1 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EER24681.1 - 0.1 12.1 0.0 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase NDUF_B7 PF05676.13 EER24683.1 - 2e-26 91.5 4.2 2.3e-26 91.3 4.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EER24683.1 - 0.016 15.2 1.8 0.021 14.9 1.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_5 PF13857.6 EER24684.1 - 2.3e-10 40.5 0.4 0.00015 22.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER24684.1 - 1.7e-09 38.1 0.0 5.9e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER24684.1 - 2.4e-08 34.4 0.1 3.5e-05 24.3 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER24684.1 - 8.8e-08 31.8 0.2 0.00049 20.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EER24684.1 - 8.3e-07 29.2 0.5 8.6e-06 26.0 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeat KilA-N PF04383.13 EER24684.1 - 1.3e-05 25.0 0.2 0.00025 20.9 0.2 2.6 1 1 0 1 1 1 1 KilA-N domain ThrE PF06738.12 EER24686.1 - 1.8e-70 237.1 12.9 5.8e-67 225.6 0.1 2.7 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EER24686.1 - 1.8e-08 34.6 11.1 1.8e-08 34.6 11.1 3.1 3 1 0 3 3 3 1 Threonine/Serine exporter, ThrE DUF997 PF06196.12 EER24686.1 - 5.4 7.1 5.9 1.9 8.5 1.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF997) Metallophos_2 PF12850.7 EER24687.1 - 2.2e-07 31.2 0.1 4.1e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EER24687.1 - 2.2e-07 31.6 2.8 8.5e-07 29.7 2.8 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PS_Dcarbxylase PF02666.15 EER24689.1 - 4.2e-55 186.4 0.0 6.2e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EER24689.1 - 1.5e-37 128.0 0.0 5.6e-18 65.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 EER24689.1 - 0.014 14.9 0.0 0.053 13.1 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EER24689.1 - 0.022 14.6 0.0 0.13 12.3 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EER24689.1 - 0.11 12.1 0.0 0.38 10.3 0.0 2.0 1 0 0 1 1 1 0 EF hand APH PF01636.23 EER24690.1 - 4.5e-07 30.0 0.3 1e-06 28.9 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER24690.1 - 0.014 15.0 0.0 0.036 13.6 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 EER24690.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 EER24691.1 - 1.2e-12 47.8 0.1 1.9e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24691.1 - 5.8e-10 38.9 0.0 8.9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EER24691.1 - 0.0027 17.3 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EER24691.1 - 0.0027 17.1 0.2 0.0056 16.0 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EER24691.1 - 0.04 13.2 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Kinase-like MIS13 PF08202.11 EER24692.1 - 2.2e-50 171.7 1.7 5.6e-50 170.3 1.6 1.6 1 1 0 1 1 1 1 Mis12-Mtw1 protein family DivIC PF04977.15 EER24692.1 - 0.012 15.4 0.3 0.025 14.3 0.3 1.5 1 0 0 1 1 1 0 Septum formation initiator IATP PF04568.12 EER24692.1 - 0.12 12.8 4.2 1 9.8 0.2 3.1 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP Sugar_tr PF00083.24 EER24693.1 - 4.5e-88 296.1 8.1 6.9e-88 295.5 8.1 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER24693.1 - 5.4e-32 111.1 39.0 1.5e-23 83.3 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EER24693.1 - 7.2e-06 25.5 1.0 7.2e-06 25.5 1.0 2.6 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EER24693.1 - 0.00096 17.6 1.1 0.00096 17.6 1.1 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 EER24694.1 - 1e-65 221.7 0.0 1.3e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24694.1 - 3e-30 105.4 0.0 4.9e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EER24694.1 - 0.0036 16.3 0.1 0.0056 15.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EER24694.1 - 0.16 11.9 0.1 0.42 10.5 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family MCM PF00493.23 EER24695.1 - 8e-101 335.8 0.0 1.6e-100 334.9 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EER24695.1 - 3.3e-38 130.4 0.1 5.8e-38 129.6 0.1 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EER24695.1 - 1.6e-26 93.4 30.5 1.6e-26 93.4 30.5 2.2 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EER24695.1 - 3.1e-24 85.2 1.7 5e-24 84.5 0.7 2.0 2 0 0 2 2 1 1 MCM AAA-lid domain MCM_N PF14551.6 EER24695.1 - 1.6e-10 41.5 0.0 5e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EER24695.1 - 5.3e-08 32.5 0.1 8e-06 25.4 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EER24695.1 - 9e-07 29.0 0.0 4.1e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EER24695.1 - 0.0003 20.7 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EER24695.1 - 0.013 15.2 0.1 0.19 11.4 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain zf-TFIIB PF13453.6 EER24695.1 - 0.084 12.2 1.7 0.17 11.2 1.7 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger AAA_30 PF13604.6 EER24695.1 - 0.16 11.6 2.8 0.23 11.2 0.5 2.3 2 0 0 2 2 2 0 AAA domain zf-UBR PF02207.20 EER24696.1 - 3.4e-14 52.7 2.7 3.4e-14 52.7 2.7 3.1 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.33 EER24697.1 - 0.093 12.6 1.4 0.25 11.3 1.4 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EER24697.1 - 0.18 11.7 2.4 0.9 9.5 2.4 2.1 1 1 0 1 1 1 0 F-box-like Meth_synt_2 PF01717.18 EER24698.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Meth_synt_2 PF01717.18 EER24699.1 - 4.9e-08 32.6 0.0 8.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EER24699.1 - 0.11 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Cobalamin-independent synthase, N-terminal domain Arf PF00025.21 EER24700.1 - 8.6e-74 246.7 0.2 1e-73 246.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EER24700.1 - 4.7e-14 52.6 0.0 6.7e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EER24700.1 - 3.1e-12 46.4 0.0 3.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EER24700.1 - 1.8e-11 43.9 0.1 2.3e-11 43.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EER24700.1 - 1.9e-11 43.7 1.7 1.7e-07 30.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EER24700.1 - 5.7e-11 42.2 0.0 7.3e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EER24700.1 - 0.00043 20.3 0.0 0.00065 19.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EER24700.1 - 0.024 13.9 0.2 0.052 12.8 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase SpoOE-like PF09388.10 EER24700.1 - 0.073 13.0 1.6 0.15 11.9 1.6 1.5 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein Hexapep PF00132.24 EER24701.1 - 4.4e-05 23.0 12.4 0.0007 19.2 2.8 4.6 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EER24701.1 - 0.00068 19.3 0.7 0.00068 19.3 0.7 2.9 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EER24701.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 L-fucokinase An_peroxidase PF03098.15 EER24702.1 - 9.1e-46 156.5 0.0 2.5e-26 92.4 0.0 3.1 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 EER24702.1 - 6.7e-12 44.9 0.0 1.9e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 PI_PP_C PF18365.1 EER24702.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain DUF2235 PF09994.9 EER24703.1 - 6.1e-97 324.4 0.4 7.7e-97 324.1 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MARVEL PF01284.23 EER24704.1 - 7.6e-05 22.8 17.2 0.0008 19.5 18.0 2.0 1 1 1 2 2 2 1 Membrane-associating domain PGA2 PF07543.12 EER24705.1 - 1.6e-45 154.5 0.8 1.8e-45 154.3 0.8 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF3245 PF11595.8 EER24705.1 - 0.018 15.5 5.6 0.018 15.5 5.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) PBP1_TM PF14812.6 EER24705.1 - 0.026 14.9 2.6 0.026 14.9 2.6 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-S PF15630.6 EER24706.1 - 5.4e-24 84.4 0.0 8.6e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EER24706.1 - 0.00021 21.4 0.1 0.00045 20.3 0.1 1.6 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Afi1 PF07792.12 EER24706.1 - 0.017 15.6 0.0 0.031 14.8 0.0 1.5 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Ribosomal_L27_C PF18471.1 EER24706.1 - 0.044 13.2 0.1 0.082 12.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain MMS1_N PF10433.9 EER24707.1 - 7.6e-131 437.1 0.0 5.6e-130 434.2 0.0 2.3 2 1 1 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EER24707.1 - 1.2e-72 245.0 0.0 1.4e-71 241.5 0.0 2.5 2 1 0 2 2 2 1 CPSF A subunit region NAD_binding_2 PF03446.15 EER24708.1 - 1.7e-35 122.5 0.0 3e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EER24708.1 - 3.3e-28 98.4 0.0 5.2e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EER24708.1 - 2.7e-05 24.7 0.0 7.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EER24708.1 - 0.0029 16.6 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 EER24708.1 - 0.017 16.0 0.0 0.033 15.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 EER24708.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EER24708.1 - 0.2 11.7 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ABC_membrane PF00664.23 EER24709.1 - 2e-94 316.3 30.8 4e-47 161.2 12.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EER24709.1 - 8.2e-62 207.7 0.0 4.4e-31 108.2 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EER24709.1 - 1e-16 61.1 0.7 4.3e-06 26.3 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EER24709.1 - 3.8e-08 33.7 0.1 0.028 14.7 0.0 3.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EER24709.1 - 6.9e-07 29.3 0.0 0.025 14.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EER24709.1 - 7e-07 29.8 0.8 0.064 13.6 0.1 3.8 4 1 0 4 4 3 2 AAA ATPase domain Rad17 PF03215.15 EER24709.1 - 9.1e-07 29.0 0.0 0.027 14.4 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_15 PF13175.6 EER24709.1 - 9.5e-07 28.8 0.0 0.044 13.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EER24709.1 - 1.1e-06 29.1 0.9 0.087 13.2 0.1 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EER24709.1 - 1.1e-05 24.4 0.1 0.093 11.5 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.6 EER24709.1 - 2.2e-05 24.4 0.0 0.12 12.2 0.0 3.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 EER24709.1 - 3.1e-05 23.6 0.1 0.051 13.1 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EER24709.1 - 3.3e-05 23.5 0.2 0.051 13.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EER24709.1 - 0.00013 22.5 0.0 0.74 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EER24709.1 - 0.00036 20.1 0.0 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_5 PF07728.14 EER24709.1 - 0.00072 19.6 0.0 3.7 7.6 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EER24709.1 - 0.0011 18.7 0.2 1.5 8.5 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 EER24709.1 - 0.0021 18.4 0.0 2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EER24709.1 - 0.0028 17.3 0.0 2 8.0 0.0 2.7 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 EER24709.1 - 0.003 17.7 1.3 1.4 9.2 0.2 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EER24709.1 - 0.005 17.2 0.0 9.9 6.6 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_14 PF13173.6 EER24709.1 - 0.0053 16.8 0.0 6 6.9 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 EER24709.1 - 0.0098 16.4 0.0 8.7 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EER24709.1 - 0.017 14.4 0.0 2 7.5 0.0 3.0 4 0 0 4 4 4 0 NB-ARC domain PRK PF00485.18 EER24709.1 - 0.048 13.4 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EER24709.1 - 0.061 12.6 0.0 14 4.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EER24709.1 - 0.07 13.3 0.0 10 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EER24709.1 - 0.11 12.2 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Tropomyosin PF00261.20 EER24710.1 - 0.034 13.5 15.1 0.035 13.5 10.0 2.4 2 0 0 2 2 2 0 Tropomyosin DUF3138 PF11336.8 EER24710.1 - 0.098 11.3 0.9 0.15 10.7 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Prefoldin_2 PF01920.20 EER24710.1 - 0.1 12.5 0.3 0.1 12.5 0.3 3.8 3 1 0 3 3 3 0 Prefoldin subunit Cep57_CLD PF14073.6 EER24710.1 - 0.24 11.4 29.7 0.75 9.8 1.0 2.8 2 1 1 3 3 3 0 Centrosome localisation domain of Cep57 Tropomyosin_1 PF12718.7 EER24710.1 - 1.4 9.1 19.3 0.67 10.1 1.4 3.9 3 1 0 4 4 4 0 Tropomyosin like DUF724 PF05266.14 EER24710.1 - 2 8.2 19.4 0.033 14.0 6.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2333 PF10095.9 EER24710.1 - 4.9 6.1 7.2 1 8.3 0.3 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) Spc7 PF08317.11 EER24710.1 - 7 5.4 18.6 29 3.4 18.6 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein FtsJ PF01728.19 EER24711.1 - 2.2e-55 187.5 0.0 2.7e-55 187.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EER24711.1 - 0.0085 15.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EER24711.1 - 0.01 15.7 0.0 0.024 14.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EER24711.1 - 0.06 14.1 0.0 2.3 9.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain OST3_OST6 PF04756.13 EER24712.1 - 2.1e-99 332.6 0.0 2.7e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EER24712.1 - 0.0011 18.9 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin DUF768 PF05589.11 EER24712.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF768) HXXEE PF13787.6 EER24712.1 - 0.091 13.6 0.8 0.091 13.6 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function with HXXEE motif VIT1 PF01988.19 EER24712.1 - 2.5 7.9 10.4 0.69 9.7 1.7 2.1 1 1 0 2 2 2 0 VIT family Acetyltransf_10 PF13673.7 EER24713.1 - 1.8e-13 50.5 0.0 2.4e-12 46.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER24713.1 - 1.1e-10 41.7 0.0 2.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER24713.1 - 1.3e-10 41.5 0.0 3.5e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EER24713.1 - 4.4e-05 23.6 0.0 0.0001 22.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER24713.1 - 0.0072 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EER24713.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SPX PF03105.19 EER24716.1 - 4.3e-39 135.5 7.9 2.4e-37 129.8 7.9 2.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 EER24716.1 - 6.8e-07 29.4 9.7 1.1e-06 28.7 8.6 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EER24716.1 - 4.6e-06 26.4 9.5 4.6e-06 26.4 9.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER24716.1 - 3.2e-05 23.7 10.2 3.2e-05 23.7 10.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER24716.1 - 9e-05 22.4 8.4 0.00032 20.7 8.4 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EER24716.1 - 0.00011 22.4 10.5 0.00033 20.9 10.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER24716.1 - 0.002 17.9 9.5 0.0052 16.6 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER24716.1 - 0.0035 17.3 10.6 0.011 15.6 10.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain CARD_2 PF16739.5 EER24716.1 - 0.052 13.5 0.0 5.5 7.0 0.0 2.8 1 1 1 2 2 2 0 Caspase recruitment domain Prok-RING_4 PF14447.6 EER24716.1 - 0.081 12.8 11.6 0.1 12.5 9.5 2.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-P11 PF03854.14 EER24716.1 - 0.96 9.2 10.0 0.73 9.5 4.6 2.5 1 1 1 2 2 2 0 P-11 zinc finger DnaJ PF00226.31 EER24717.1 - 1.1e-22 79.9 0.2 2.6e-22 78.7 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.7 EER24717.1 - 5.6e-10 39.3 7.9 5.3e-09 36.2 2.0 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EER24717.1 - 6.7e-10 39.0 5.0 6.7e-10 39.0 5.0 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EER24717.1 - 1e-05 25.8 9.7 0.00047 20.4 2.3 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EER24717.1 - 0.00025 21.6 9.7 0.033 15.0 0.7 3.2 3 0 0 3 3 2 2 C2H2-type zinc finger PLATZ PF04640.14 EER24717.1 - 0.013 16.1 3.3 0.22 12.2 0.3 3.0 2 0 0 2 2 2 0 PLATZ transcription factor zf-C2H2 PF00096.26 EER24717.1 - 0.019 15.4 12.8 0.026 15.0 1.3 3.1 3 0 0 3 3 2 0 Zinc finger, C2H2 type DUF3449 PF11931.8 EER24717.1 - 0.019 14.7 1.2 0.18 11.6 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) DUF2256 PF10013.9 EER24717.1 - 0.04 14.0 0.7 10 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_Hakai PF18408.1 EER24717.1 - 0.054 13.2 1.4 3.9 7.2 0.2 2.6 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain Trm112p PF03966.16 EER24717.1 - 0.089 13.4 0.0 0.61 10.7 0.0 2.4 1 1 1 2 2 2 0 Trm112p-like protein zf-C2H2_6 PF13912.6 EER24717.1 - 3.2 7.9 11.5 0.78 9.8 2.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger R3H PF01424.22 EER24718.1 - 1.4e-11 44.2 0.1 3.4e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EER24718.1 - 3.4e-08 33.3 0.7 1.3e-07 31.4 0.1 2.2 2 0 0 2 2 2 1 G-patch domain CENP-B_dimeris PF09026.10 EER24718.1 - 0.0076 16.6 9.4 0.021 15.2 9.4 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Rad60-SLD PF11976.8 EER24719.1 - 7.1e-20 70.6 0.1 2.9e-19 68.7 0.3 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EER24719.1 - 0.00048 19.8 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Trm112p PF03966.16 EER24720.1 - 9.7e-16 58.1 0.1 1.2e-15 57.8 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 EER24720.1 - 0.044 14.3 0.3 0.078 13.5 0.3 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain N-SET PF11764.8 EER24721.1 - 1.2e-57 194.8 1.7 2.6e-57 193.7 1.7 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EER24721.1 - 1.8e-29 101.2 0.5 4.2e-29 100.0 0.5 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 EER24721.1 - 7.1e-20 72.1 1.7 2.2e-19 70.5 0.2 2.7 2 0 0 2 2 2 1 SET domain RRM_1 PF00076.22 EER24721.1 - 0.00063 19.5 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SIS PF01380.22 EER24723.1 - 1.1e-57 193.5 0.0 5.3e-32 110.4 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EER24723.1 - 1.3e-17 64.2 0.0 2.6e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EER24723.1 - 1.4e-10 41.1 0.0 3.4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EER24723.1 - 0.00081 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DMRL_synthase PF00885.19 EER24724.1 - 2.7e-53 179.6 0.3 5.6e-53 178.6 0.3 1.4 1 1 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.26 EER24725.1 - 3.2e-45 154.0 0.3 1.5e-31 109.3 0.0 2.5 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 EER24725.1 - 5.5e-12 45.1 1.0 6.3e-12 44.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Lar_restr_allev PF14354.6 EER24726.1 - 0.14 12.6 0.3 0.4 11.1 0.3 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 EER24726.1 - 1.4 8.5 4.5 2.9 7.4 0.9 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EER24726.1 - 5.7 6.8 6.0 7 6.5 1.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Iso_dh PF00180.20 EER24727.1 - 3.7e-84 282.9 0.1 4.6e-84 282.5 0.1 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Erv26 PF04148.13 EER24728.1 - 9.5e-90 299.9 0.0 1.1e-89 299.7 0.0 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 WBS_methylT PF12589.8 EER24729.1 - 2.6e-15 57.0 2.9 4.5e-15 56.2 2.9 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 EER24729.1 - 5.3e-10 39.9 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER24729.1 - 7.3e-10 39.4 0.0 1.3e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER24729.1 - 0.00022 21.9 0.0 0.00057 20.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER24729.1 - 0.0004 20.2 0.0 0.0011 18.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EER24729.1 - 0.00041 20.2 0.0 0.0007 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EER24729.1 - 0.0034 17.2 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER24729.1 - 0.013 14.8 0.0 0.049 13.0 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EER24729.1 - 0.1 11.8 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RhoGAP PF00620.27 EER24730.1 - 5.6e-41 139.9 0.1 1.3e-40 138.7 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EER24730.1 - 6.7e-13 49.1 0.0 1.7e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 PH domain PX PF00787.24 EER24730.1 - 0.0067 16.4 0.0 0.017 15.1 0.0 1.7 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 EER24730.1 - 0.049 13.9 0.0 0.14 12.5 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain MDM31_MDM32 PF08118.11 EER24731.1 - 4.1e-256 850.7 0.0 6.3e-256 850.1 0.0 1.3 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_8 PF17903.1 EER24732.1 - 5.4e-06 26.4 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EER24732.1 - 0.16 11.8 1.1 0.36 10.7 1.1 1.6 1 0 0 1 1 1 0 KH domain Proteasome PF00227.26 EER24733.1 - 2e-31 108.9 0.1 1.3e-30 106.3 0.1 2.0 1 1 0 1 1 1 1 Proteasome subunit HCNGP PF07818.13 EER24734.1 - 3.7e-27 94.8 0.1 7.8e-27 93.8 0.1 1.5 1 0 0 1 1 1 1 HCNGP-like protein Proteasome PF00227.26 EER24735.1 - 8.3e-29 100.4 0.0 1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit NEXCaM_BD PF16644.5 EER24735.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin FAA_hydrolase PF01557.18 EER24736.1 - 4.8e-65 219.3 0.0 6.2e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 EER24736.1 - 0.0029 18.0 0.1 0.005 17.3 0.1 1.4 1 0 0 1 1 1 1 Type II transport protein GspH DUF2437 PF10370.9 EER24736.1 - 0.026 15.4 0.1 0.12 13.3 0.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF2437) Complex1_LYR PF05347.15 EER24737.1 - 7e-18 64.4 4.6 1.4e-17 63.5 4.6 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EER24737.1 - 7.9e-07 29.7 0.6 9.4e-07 29.5 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Ferritin_2 PF13668.6 EER24738.1 - 2.9e-16 59.9 0.4 4.4e-16 59.3 0.4 1.2 1 0 0 1 1 1 1 Ferritin-like domain RRM_1 PF00076.22 EER24739.1 - 1.8e-08 34.1 0.1 3.8e-08 33.0 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER24739.1 - 6.5e-05 22.5 0.0 8.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EER24740.1 - 2.3e-14 53.5 10.4 0.0028 18.4 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER24740.1 - 1.7e-07 31.5 0.0 0.0052 17.0 0.0 4.4 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Lipase_3 PF01764.25 EER24741.1 - 1.7e-31 109.0 0.0 2.8e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EER24741.1 - 0.00038 21.1 0.3 0.00058 20.5 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EER24741.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EER24741.1 - 0.027 14.6 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 EER24741.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EER24741.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EER24741.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 EER24741.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase WW PF00397.26 EER24742.1 - 1.1e-11 44.6 0.6 2.5e-11 43.5 0.6 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 EER24742.1 - 0.11 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoD-like phosphatase Ecm29 PF13001.7 EER24743.1 - 3.5e-151 504.3 5.3 1.8e-150 501.9 0.2 3.4 4 0 0 4 4 4 1 Proteasome stabiliser HEAT PF02985.22 EER24743.1 - 9.2e-05 22.4 10.9 1.6 9.2 0.0 9.1 10 0 0 10 10 10 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EER24743.1 - 0.002 18.7 5.1 12 6.6 0.1 5.9 6 1 0 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EER24743.1 - 0.085 13.4 11.5 1.2e+02 3.3 0.0 7.9 7 2 2 9 9 9 0 HEAT-like repeat Sec7_N PF12783.7 EER24743.1 - 0.18 11.7 3.1 6.3 6.7 0.2 3.3 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal IFRD PF05004.13 EER24743.1 - 3.5 6.6 6.5 36 3.3 0.0 4.7 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) Frag1 PF10277.9 EER24744.1 - 3.4e-45 154.3 10.9 4e-45 154.0 10.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family TssN PF17555.2 EER24744.1 - 0.049 13.0 2.3 0.08 12.3 2.3 1.2 1 0 0 1 1 1 0 Type VI secretion system, TssN DUF2070 PF09843.9 EER24744.1 - 0.14 10.4 13.3 0.033 12.5 7.5 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) DnaJ PF00226.31 EER24746.1 - 3.3e-10 39.9 0.6 2.9e-09 36.9 0.0 2.6 3 0 0 3 3 3 1 DnaJ domain DnaJ PF00226.31 EER24748.1 - 2.7e-07 30.6 0.4 6.4e-07 29.4 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EER24748.1 - 0.0026 18.1 1.6 0.0037 17.6 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 EER24748.1 - 0.0041 17.2 5.0 0.0067 16.5 5.0 1.4 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide HlyE PF06109.13 EER24748.1 - 0.08 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) Rick_17kDa_Anti PF05433.15 EER24748.1 - 0.099 12.5 1.3 0.099 12.5 1.3 2.4 2 1 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EER24748.1 - 4.7 7.3 14.2 16 5.6 14.2 1.9 1 1 0 1 1 1 0 Glycine zipper MFS_1 PF07690.16 EER24749.1 - 9.4e-36 123.5 65.5 1.4e-35 122.8 61.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily PMM PF03332.13 EER24750.1 - 4.2e-102 340.6 0.2 4.9e-102 340.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EER24750.1 - 0.0012 18.6 0.0 0.0072 16.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.7 EER24751.1 - 1.6e-08 34.3 1.3 6.8e-08 32.3 0.4 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EER24751.1 - 0.00016 21.4 0.1 0.0006 19.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain CSTF1_dimer PF16699.5 EER24751.1 - 0.0045 16.7 0.0 0.14 11.9 0.0 2.5 2 0 0 2 2 2 1 Cleavage stimulation factor subunit 1, dimerisation domain DUF1640 PF07798.11 EER24752.1 - 3.1e-56 190.2 5.7 3.9e-56 189.9 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SNF2_N PF00176.23 EER24754.1 - 9.7e-60 202.1 0.0 1.8e-59 201.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER24754.1 - 1.4e-05 25.4 0.0 4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Alpha-mann_mid PF09261.11 EER24754.1 - 1.7 8.8 4.9 1.6 9.0 0.1 3.1 3 0 0 3 3 3 0 Alpha mannosidase middle domain Eisosome1 PF12757.7 EER24755.1 - 1.3e-27 96.5 3.4 1.3e-27 96.5 3.4 4.7 4 1 0 5 5 5 2 Eisosome protein 1 Borrelia_P83 PF05262.11 EER24755.1 - 0.52 8.8 14.9 0.22 10.0 12.3 1.7 2 0 0 2 2 2 0 Borrelia P83/100 protein MAGI_u1 PF16663.5 EER24755.1 - 5.4 7.2 10.0 3.1 7.9 0.6 4.1 4 0 0 4 4 4 0 Unstructured region on MAGI Pkinase PF00069.25 EER24756.1 - 1.5e-66 224.4 0.0 2.2e-66 223.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24756.1 - 4.7e-42 144.1 0.0 6.8e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER24756.1 - 1.9e-08 34.0 0.0 6.5e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EER24756.1 - 2.9e-06 26.5 0.2 2.9e-06 26.5 0.2 2.1 3 0 0 3 3 3 1 Haspin like kinase domain Kdo PF06293.14 EER24756.1 - 0.068 12.5 2.2 0.17 11.2 0.0 2.3 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRKG1_interact PF15898.5 EER24756.1 - 0.23 12.3 5.6 0.82 10.6 5.6 1.9 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain APH PF01636.23 EER24756.1 - 0.47 10.3 7.3 1.2 9.0 0.2 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EER24756.1 - 3.4 7.2 4.9 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Condensation PF00668.20 EER24757.1 - 2e-69 234.4 0.0 2.1e-35 122.3 0.0 2.1 2 0 0 2 2 2 2 Condensation domain AMP-binding PF00501.28 EER24757.1 - 5.5e-66 222.9 0.2 8.4e-66 222.3 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EER24757.1 - 1e-20 73.9 1.7 1e-09 38.6 0.1 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site Colipase-like PF15083.6 EER24757.1 - 0.98 9.6 3.3 1.8 8.7 1.0 2.3 2 0 0 2 2 2 0 Colipase-like FAD_binding_3 PF01494.19 EER24758.1 - 7.4e-09 35.3 0.2 1.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EER24758.1 - 0.00016 21.3 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF4434 PF14488.6 EER24758.1 - 0.0035 17.4 0.0 0.0086 16.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) SE PF08491.10 EER24758.1 - 0.052 12.6 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Trp_DMAT PF11991.8 EER24759.1 - 3.3e-96 322.9 0.0 4.2e-96 322.5 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF4611 PF15387.6 EER24760.1 - 1.1 9.6 11.3 4.8 7.5 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 EER24760.1 - 2.9 5.9 12.6 3.9 5.5 12.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 EER24760.1 - 7.1 7.1 16.7 11 6.4 3.1 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Spt5_N PF11942.8 EER24760.1 - 8.3 7.5 13.7 6.6 7.8 0.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Prenyltrans PF00432.21 EER24761.1 - 2.3e-26 91.2 14.1 7.2e-08 32.0 0.3 6.4 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EER24761.1 - 0.0022 17.2 0.0 0.036 13.2 0.0 2.8 3 1 1 4 4 4 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EER24761.1 - 0.006 15.7 0.0 1 8.4 0.0 2.9 3 0 0 3 3 3 1 Squalene-hopene cyclase N-terminal domain OmdA PF13376.6 EER24761.1 - 0.16 12.0 0.1 23 5.1 0.0 2.5 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Ilm1 PF10311.9 EER24762.1 - 2.9e-49 166.9 0.3 3.6e-49 166.6 0.3 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 CFEM PF05730.11 EER24763.1 - 3.3e-14 52.7 12.8 6.5e-14 51.8 12.8 1.5 1 0 0 1 1 1 1 CFEM domain DEC-1_N PF04625.13 EER24763.1 - 0.099 11.6 5.3 0.12 11.4 5.3 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region MFS_1 PF07690.16 EER24764.1 - 4.1e-31 108.2 22.2 4.1e-31 108.2 22.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER24764.1 - 1.7e-07 30.5 13.0 1.7e-07 30.5 13.0 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 EER24765.1 - 1e-06 28.0 14.5 1e-06 28.0 14.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RCR PF12273.8 EER24766.1 - 0.17 12.6 8.2 0.034 14.8 2.3 2.6 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Tyrosinase PF00264.20 EER24767.1 - 3.3e-34 119.1 0.0 2.4e-33 116.3 0.0 2.1 1 1 1 2 2 2 1 Common central domain of tyrosinase E1-E2_ATPase PF00122.20 EER24769.1 - 3.2e-53 179.9 6.7 4e-52 176.4 2.3 3.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EER24769.1 - 5.1e-46 156.7 9.4 5.1e-46 156.7 9.4 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EER24769.1 - 1.4e-22 81.0 0.7 1.2e-21 78.0 0.7 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EER24769.1 - 4.8e-20 71.0 0.1 1.5e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EER24769.1 - 1.4e-19 69.9 0.0 3.4e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EER24769.1 - 2.1e-08 34.2 1.2 4.6e-06 26.6 0.8 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EER24769.1 - 1.1e-06 29.2 0.0 5.1e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ATG27 PF09451.10 EER24769.1 - 0.17 11.7 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 Autophagy-related protein 27 14-3-3 PF00244.20 EER24770.1 - 2.5e-107 357.4 3.1 3e-107 357.2 3.1 1.1 1 0 0 1 1 1 1 14-3-3 protein CAP18_C PF12153.8 EER24770.1 - 0.036 13.9 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Ima1_N PF09779.9 EER24770.1 - 0.32 11.8 1.8 5.1 8.0 0.0 3.1 4 0 0 4 4 4 0 Ima1 N-terminal domain eIF3_subunit PF08597.10 EER24771.1 - 1.7e-69 234.4 31.3 1.9e-69 234.2 31.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF572 PF04502.13 EER24771.1 - 5.5 6.5 21.0 7.1 6.2 21.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Enolase_C PF00113.22 EER24772.1 - 6.9e-151 501.5 0.1 9.3e-151 501.1 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EER24772.1 - 3.7e-57 192.1 0.2 5.9e-57 191.5 0.2 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EER24772.1 - 8.9e-08 32.0 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EER24772.1 - 0.00065 18.9 1.0 0.012 14.8 0.1 2.7 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus AAA PF00004.29 EER24773.1 - 6.2e-43 146.4 0.0 1.2e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EER24773.1 - 6.6e-12 45.2 0.1 8.4e-11 41.7 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EER24773.1 - 3.5e-10 39.5 0.1 9e-10 38.2 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 EER24773.1 - 6.6e-08 33.1 0.0 6e-05 23.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EER24773.1 - 1.6e-06 28.1 0.1 3.8e-05 23.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EER24773.1 - 2.6e-06 27.7 0.0 9.3e-06 25.9 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EER24773.1 - 6.6e-06 26.0 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EER24773.1 - 0.00021 20.5 0.0 0.00066 18.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EER24773.1 - 0.00022 21.5 0.1 0.0061 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EER24773.1 - 0.00058 20.4 0.0 0.0026 18.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EER24773.1 - 0.00089 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EER24773.1 - 0.0023 17.2 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EER24773.1 - 0.0037 17.4 0.0 0.01 16.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 EER24773.1 - 0.0038 17.2 0.0 0.0089 16.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EER24773.1 - 0.0045 16.4 0.0 0.0086 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 EER24773.1 - 0.0047 16.5 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain IstB_IS21 PF01695.17 EER24773.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EER24773.1 - 0.006 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 EER24773.1 - 0.0069 16.2 0.5 0.26 11.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EER24773.1 - 0.0075 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EER24773.1 - 0.0081 15.9 0.0 0.031 14.0 0.0 1.9 1 1 1 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EER24773.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EER24773.1 - 0.017 14.9 0.0 0.058 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EER24773.1 - 0.03 14.0 0.1 3.8 7.1 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase ATPase PF06745.13 EER24773.1 - 0.031 13.6 0.4 0.14 11.5 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_30 PF13604.6 EER24773.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 EER24773.1 - 0.045 14.2 2.0 0.045 14.2 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) NACHT PF05729.12 EER24773.1 - 0.055 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EER24773.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EER24773.1 - 0.079 12.5 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EER24773.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EER24773.1 - 0.085 12.8 0.2 0.39 10.6 0.0 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EER24773.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Parvo_NS1 PF01057.17 EER24773.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CENP-Q PF13094.6 EER24773.1 - 0.23 11.7 1.8 2.7 8.2 1.9 2.5 4 0 0 4 4 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4482 PF14818.6 EER24773.1 - 0.75 10.7 3.3 0.32 11.9 0.5 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4482) AAA_23 PF13476.6 EER24773.1 - 1.3 9.5 6.2 14 6.1 2.0 2.7 2 1 0 2 2 2 0 AAA domain OmpH PF03938.14 EER24773.1 - 4.1 7.8 8.4 2.2 8.6 3.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Glyco_hydro_47 PF01532.20 EER24774.1 - 3.1e-168 560.4 0.0 3.6e-168 560.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.6 EER24774.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) M20_dimer PF07687.14 EER24775.1 - 3.4e-20 72.0 0.2 2.2e-18 66.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EER24775.1 - 5.9e-15 55.5 0.1 1.8e-14 54.0 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EER24775.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 TRAP_alpha PF03896.16 EER24776.1 - 1.4e-14 54.0 0.0 2.1e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit BBP1_C PF15272.6 EER24777.1 - 0.017 14.9 1.4 0.017 14.9 1.4 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal POT1PC PF16686.5 EER24778.1 - 3.7e-47 160.1 0.1 1.1e-46 158.5 0.1 1.8 2 0 0 2 2 2 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EER24778.1 - 2e-18 66.6 0.0 9.4e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 EER24778.1 - 0.094 12.7 0.0 36 4.4 0.0 3.3 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Arm PF00514.23 EER24779.1 - 1e-93 304.9 11.7 4.1e-14 52.0 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EER24779.1 - 3e-24 85.3 1.7 7.4e-24 84.0 1.7 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 EER24779.1 - 8.9e-24 82.8 3.2 2.1e-23 81.6 3.2 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 EER24779.1 - 4.3e-23 81.4 2.3 1.5e-09 38.2 0.1 5.9 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 EER24779.1 - 4.2e-21 75.1 0.1 9.5e-09 35.5 0.0 5.1 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.22 EER24779.1 - 2.6e-20 70.7 0.1 3.5e-06 26.8 0.0 6.6 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.13 EER24779.1 - 6e-09 35.7 0.0 0.0022 17.5 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 EER24779.1 - 3.1e-05 24.0 0.0 1.3 9.2 0.0 4.5 3 2 2 5 5 5 2 V-ATPase subunit H Cnd1 PF12717.7 EER24779.1 - 0.00084 19.4 0.0 4.7 7.2 0.0 3.2 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 EER24779.1 - 0.0019 18.4 1.6 1.1 9.6 0.0 4.7 4 1 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 EER24779.1 - 0.0033 17.9 4.1 0.98 10.3 0.1 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat NopRA1 PF16201.5 EER24779.1 - 0.016 14.8 0.0 19 4.7 0.0 3.8 1 1 3 4 4 4 0 Nucleolar pre-ribosomal-associated protein 1 Glycos_trans_3N PF02885.17 EER24779.1 - 0.16 11.8 0.0 33 4.4 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Amidase PF01425.21 EER24780.1 - 2.9e-111 372.6 0.0 5.2e-111 371.8 0.0 1.4 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.16 EER24781.1 - 4.9e-32 111.2 28.4 4.9e-32 111.2 28.4 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EER24781.1 - 2.9e-06 26.8 0.8 2.9e-06 26.8 0.8 2.3 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB SLAC1 PF03595.17 EER24782.1 - 4.4e-98 328.5 59.8 5e-98 328.3 59.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel MoaE PF02391.17 EER24783.1 - 2.7e-35 121.1 0.0 3.2e-35 120.8 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.14 EER24784.1 - 8.7e-46 155.2 0.0 1.3e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EER24784.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.6 1 1 0 1 1 1 0 AhpC/TSA family IFT57 PF10498.9 EER24784.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Thioredoxin_8 PF13905.6 EER24784.1 - 0.14 12.5 0.0 0.34 11.3 0.0 1.7 1 1 0 1 1 1 0 Thioredoxin-like UPF0184 PF03670.13 EER24785.1 - 0.0003 21.1 0.2 0.36 11.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0184) Ndc1_Nup PF09531.10 EER24786.1 - 1.4 7.5 10.2 3.1 6.4 10.2 1.7 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Yae1_N PF09811.9 EER24787.1 - 1.7e-13 50.0 0.1 2.4e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal CBM_21 PF03370.13 EER24788.1 - 2.6e-25 88.8 1.1 5.2e-25 87.8 1.1 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EER24788.1 - 4.1e-09 36.9 0.6 7.4e-09 36.1 0.6 1.4 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Acetyltransf_3 PF13302.7 EER24789.1 - 3.9e-31 108.6 0.0 4.7e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER24789.1 - 2.4e-05 24.5 0.0 7.3e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Clp1 PF06807.14 EER24789.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 zf-RanBP PF00641.18 EER24791.1 - 1.4e-10 40.3 1.3 3.1e-10 39.2 1.3 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch PF01585.23 EER24791.1 - 7.1e-10 38.6 5.6 8.7e-10 38.3 3.9 2.1 2 0 0 2 2 2 1 G-patch domain RRM_1 PF00076.22 EER24791.1 - 5.6e-09 35.7 0.0 0.00028 20.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EER24791.1 - 1.7e-05 24.8 1.6 6.4e-05 23.0 1.6 2.1 1 0 0 1 1 1 1 G-patch domain Rad50_zn_hook PF04423.14 EER24791.1 - 0.057 13.3 0.3 0.2 11.5 0.3 2.0 1 0 0 1 1 1 0 Rad50 zinc hook motif DUF3433 PF11915.8 EER24792.1 - 1.9e-31 108.4 16.8 1.5e-25 89.4 5.5 3.9 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Glyco_hydro_18 PF00704.28 EER24794.1 - 4.2e-17 62.9 0.2 1.7e-16 60.9 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_M35 PF02102.15 EER24795.1 - 5.8e-108 361.0 2.6 6.7e-108 360.8 2.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EER24795.1 - 7.8e-41 140.0 2.3 1.2e-40 139.4 2.3 1.2 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase ECH_1 PF00378.20 EER24798.1 - 1e-36 126.6 0.0 6.4e-36 123.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER24798.1 - 3.6e-29 102.3 0.0 7.8e-28 97.9 0.0 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Tfb5 PF06331.12 EER24799.1 - 2.4e-24 85.1 0.6 2.7e-24 84.9 0.6 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Toxin_trans PF07952.12 EER24799.1 - 0.11 11.6 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Aa_trans PF01490.18 EER24800.1 - 6.3e-36 124.0 29.2 8.4e-36 123.5 29.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EER24800.1 - 0.0017 17.5 17.9 0.0017 17.5 17.9 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CAAD PF14159.6 EER24800.1 - 0.023 14.5 7.0 0.19 11.6 0.7 3.3 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PHO4 PF01384.20 EER24801.1 - 5.5e-110 367.6 10.2 6.4e-110 367.3 10.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 EER24801.1 - 0.00037 20.9 1.0 0.0026 18.1 0.0 2.8 2 2 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Glycophorin_A PF01102.18 EER24801.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A COesterase PF00135.28 EER24802.1 - 2.4e-83 280.8 1.1 5.3e-72 243.3 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EER24802.1 - 1.1e-07 31.9 0.0 1.7e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Beta-lactamase PF00144.24 EER24805.1 - 3.3e-13 49.6 0.0 5.9e-13 48.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase CsiV PF10972.8 EER24805.1 - 0.054 13.2 0.2 0.054 13.2 0.2 1.1 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV Kelch_2 PF07646.15 EER24805.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Kelch motif FMO-like PF00743.19 EER24806.1 - 4.8e-05 22.0 0.0 0.00016 20.2 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EER24806.1 - 0.0026 18.0 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EER24806.1 - 0.17 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EER24806.1 - 0.17 11.9 0.0 0.92 9.6 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1601 PF07671.11 EER24807.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1601) HET PF06985.11 EER24808.1 - 7e-08 32.9 0.1 2.1e-06 28.2 0.0 2.5 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 EER24809.1 - 2.4e-14 53.9 0.0 4.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family GGACT PF06094.12 EER24810.1 - 2.4e-11 44.3 0.0 2.9e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like APH PF01636.23 EER24811.1 - 2.2e-16 60.5 0.0 4.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER24811.1 - 0.0073 15.9 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase HSP70 PF00012.20 EER24812.1 - 3.7e-11 41.9 0.2 2.2e-05 22.9 0.0 2.9 1 1 2 3 3 3 3 Hsp70 protein DUF4788 PF16032.5 EER24812.1 - 0.17 10.8 0.0 14 4.5 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4788) Zn_clus PF00172.18 EER24816.1 - 0.069 13.3 9.9 0.14 12.3 9.9 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup160 PF11715.8 EER24818.1 - 1e-113 380.9 0.2 1.5e-113 380.3 0.2 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SIR2 PF02146.17 EER24819.1 - 7.3e-28 97.7 0.0 2.8e-27 95.8 0.0 1.8 1 1 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.23 EER24820.1 - 1.9e-07 31.2 0.0 3.5e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EER24820.1 - 0.054 13.8 0.0 0.054 13.8 0.0 2.9 4 0 0 4 4 4 0 Core histone H2A/H2B/H3/H4 YqzE PF14038.6 EER24820.1 - 0.092 12.8 0.2 0.81 9.7 0.7 2.3 3 0 0 3 3 3 0 YqzE-like protein Nop14 PF04147.12 EER24820.1 - 3.8 5.6 39.3 5.2 5.1 39.3 1.2 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 EER24820.1 - 8.9 6.6 26.6 9 6.6 5.4 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 GN3L_Grn1 PF08701.11 EER24821.1 - 1.3e-24 86.0 13.1 2.8e-24 85.0 13.1 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EER24821.1 - 7.8e-17 61.4 0.0 9.1e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER24821.1 - 1.9e-07 31.1 0.0 9.9e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EER24821.1 - 1.1e-06 28.8 2.3 0.48 10.5 0.1 3.8 4 0 0 4 4 4 3 Dynamin family GTP_EFTU PF00009.27 EER24821.1 - 8.3e-05 22.2 0.0 0.15 11.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EER24821.1 - 0.00017 21.1 0.0 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 EER24821.1 - 0.024 14.8 0.0 8.1 6.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EER24821.1 - 0.043 13.4 0.0 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EER24821.1 - 0.044 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EER24821.1 - 0.12 11.4 0.0 0.31 10.0 0.0 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Torsin PF06309.11 EER24821.1 - 0.12 12.5 0.1 0.27 11.3 0.1 1.5 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.6 EER24821.1 - 0.13 12.6 1.9 0.64 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain CPL PF08144.11 EER24822.1 - 6.3e-28 97.9 0.0 1.5e-24 87.0 0.0 3.3 3 0 0 3 3 3 2 CPL (NUC119) domain Med16 PF11635.8 EER24823.1 - 1.8e-174 581.7 0.0 2.2e-174 581.5 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 ANAPC4_WD40 PF12894.7 EER24823.1 - 0.00071 19.8 0.0 3 8.2 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ATP-synt_10 PF05176.14 EER24824.1 - 4.6e-77 258.7 0.0 5.8e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.8 EER24825.1 - 1.1e-13 51.2 0.4 1.1e-13 51.2 0.4 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 EER24825.1 - 0.0047 15.6 6.1 0.0069 15.1 6.1 1.2 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 ATP-synt_D PF01813.17 EER24825.1 - 0.018 14.9 1.7 0.018 14.9 1.7 1.8 2 1 0 2 2 2 0 ATP synthase subunit D Sec20 PF03908.13 EER24825.1 - 0.033 14.1 2.7 3.8 7.5 0.0 3.2 2 1 0 3 3 3 0 Sec20 Surfac_D-trimer PF09006.11 EER24825.1 - 0.14 12.1 0.9 4 7.4 0.1 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation PEP-utilisers_N PF05524.13 EER24825.1 - 0.19 11.9 1.6 0.26 11.5 0.4 1.8 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Not3 PF04065.15 EER24825.1 - 0.27 10.6 3.8 2.9 7.3 0.8 2.1 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Ribosomal_L29 PF00831.23 EER24826.1 - 1.2e-17 63.6 0.2 1.2e-17 63.6 0.2 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.10 EER24826.1 - 0.066 13.4 1.9 0.085 13.1 0.7 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil TetR_C_24 PF17932.1 EER24826.1 - 0.17 12.2 1.1 0.26 11.5 0.6 1.5 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain HAD_2 PF13419.6 EER24827.1 - 6.3e-21 75.2 0.0 1.1e-20 74.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EER24827.1 - 2.4e-10 41.1 0.1 1e-06 29.2 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EER24827.1 - 4.6e-07 30.4 0.0 6.3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER24827.1 - 0.00034 20.6 0.0 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EER24827.1 - 0.0032 17.6 0.0 0.69 10.0 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Homeodomain PF00046.29 EER24828.1 - 1.6e-16 59.9 4.3 3.6e-16 58.7 4.3 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EER24828.1 - 5.5e-05 23.0 1.2 0.0002 21.2 1.2 2.0 1 0 0 1 1 1 1 Homeobox KN domain CK1gamma_C PF12605.8 EER24828.1 - 7.8 7.7 13.9 7.7 7.8 6.4 2.9 1 1 1 2 2 2 0 Casein kinase 1 gamma C terminal CRC_subunit PF08624.10 EER24829.1 - 2.7e-52 176.8 0.3 4.1e-52 176.2 0.3 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SLD3 PF08639.10 EER24831.1 - 1.8e-148 495.7 2.6 2.2e-148 495.4 2.6 1.1 1 0 0 1 1 1 1 DNA replication regulator SLD3 S-AdoMet_synt_C PF02773.16 EER24832.1 - 6e-67 223.9 0.7 5.1e-66 220.9 0.1 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EER24832.1 - 2.9e-46 156.6 0.0 5.6e-46 155.7 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EER24832.1 - 2.9e-44 149.8 0.4 7.3e-44 148.5 0.1 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EER24832.1 - 0.078 11.8 0.3 0.69 8.6 0.1 2.1 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) ATP_bind_1 PF03029.17 EER24833.1 - 3.6e-76 256.1 0.0 4.1e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EER24833.1 - 4.7e-05 23.3 0.0 9.2e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EER24833.1 - 0.00022 21.3 0.0 0.00053 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EER24833.1 - 0.00042 20.7 0.0 0.001 19.5 0.0 1.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EER24833.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EER24833.1 - 0.0018 18.8 0.0 0.0037 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EER24833.1 - 0.0022 18.4 0.0 0.0038 17.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 EER24833.1 - 0.0034 17.4 0.0 0.004 17.2 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EER24833.1 - 0.0063 16.7 0.0 0.0083 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EER24833.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase SRP54 PF00448.22 EER24833.1 - 0.0081 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EER24833.1 - 0.0085 16.4 0.0 0.053 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EER24833.1 - 0.0089 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EER24833.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EER24833.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 EER24833.1 - 0.016 14.8 0.0 5.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_31 PF13614.6 EER24833.1 - 0.019 14.9 0.0 2.2 8.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EER24833.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 EER24833.1 - 0.023 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 TsaE PF02367.17 EER24833.1 - 0.029 14.4 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EER24833.1 - 0.037 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EER24833.1 - 0.042 14.4 0.0 0.084 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter IstB_IS21 PF01695.17 EER24833.1 - 0.053 13.3 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 EER24833.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 KaiC KAP_NTPase PF07693.14 EER24833.1 - 0.076 12.2 0.0 0.12 11.6 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain ATPase_2 PF01637.18 EER24833.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EER24833.1 - 0.097 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase Sigma54_activat PF00158.26 EER24833.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 EER24833.1 - 0.11 12.0 0.1 0.58 9.7 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArsA_ATPase PF02374.15 EER24833.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_29 PF13555.6 EER24833.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 2 0 0 2 2 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EER24833.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EER24833.1 - 0.14 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 EER24833.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase Septin PF00735.18 EER24833.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Septin Ferric_reduct PF01794.19 EER24834.1 - 2.1e-18 66.6 16.4 2.1e-18 66.6 16.4 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EER24834.1 - 7.6e-14 52.1 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EER24834.1 - 4.9e-07 29.8 0.0 0.015 15.4 0.0 2.5 2 0 0 2 2 2 2 FAD-binding domain V-ATPase_H_N PF03224.14 EER24836.1 - 6.1e-80 268.8 0.0 1.1e-79 268.0 0.0 1.4 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EER24836.1 - 4.2e-37 126.8 0.0 1.7e-36 124.9 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H TMF_TATA_bd PF12325.8 EER24837.1 - 3.5e-39 133.6 10.1 3.5e-39 133.6 10.1 6.8 2 1 6 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EER24837.1 - 2.2e-22 78.8 12.4 2.2e-22 78.8 12.4 8.5 5 2 2 8 8 8 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EER24837.1 - 0.00011 22.5 4.1 0.00011 22.5 4.1 6.2 3 1 4 7 7 7 1 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 EER24837.1 - 0.0053 16.8 13.4 0.014 15.5 0.9 4.4 5 0 0 5 5 5 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EER24837.1 - 0.0059 16.6 2.8 0.0059 16.6 2.8 5.7 2 1 5 7 7 7 1 Protein of unknown function (DUF1664) DUF1654 PF07867.11 EER24837.1 - 0.026 14.2 0.6 0.085 12.6 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) DUF3198 PF11433.8 EER24837.1 - 0.039 13.9 3.2 1.9 8.5 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Sugarporin_N PF11471.8 EER24837.1 - 1 9.4 18.4 2.5 8.1 3.4 3.7 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension Ank_2 PF12796.7 EER24838.1 - 1e-40 138.2 0.6 6e-14 52.4 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER24838.1 - 3.1e-31 107.0 9.4 8.8e-10 38.7 0.1 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EER24838.1 - 4e-30 103.8 6.5 6.7e-08 32.9 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER24838.1 - 1.7e-24 83.2 0.8 6.2e-05 23.1 0.0 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 EER24838.1 - 1.8e-20 72.4 1.7 1.8e-05 24.9 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat WD40 PF00400.32 EER24839.1 - 1.1e-45 152.6 12.3 2e-09 37.9 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER24839.1 - 1.7e-06 28.2 0.4 4 7.8 0.0 5.0 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER24839.1 - 0.0029 16.3 1.2 8.6 4.9 0.0 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 M-factor PF03855.13 EER24839.1 - 0.059 13.5 0.5 0.15 12.2 0.5 1.6 1 0 0 1 1 1 0 M-factor WD40_like PF17005.5 EER24839.1 - 0.18 11.1 0.0 0.5 9.6 0.0 1.8 2 1 0 2 2 2 0 WD40-like domain AAA PF00004.29 EER24840.1 - 9.7e-16 58.4 0.0 1.8e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EER24840.1 - 2.7e-12 46.7 0.2 6.8e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 AAA lid domain AAA_16 PF13191.6 EER24840.1 - 1.2e-09 38.8 0.0 9.4e-09 35.9 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EER24840.1 - 2.7e-08 34.2 0.0 6.1e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EER24840.1 - 0.00029 21.2 0.0 0.00093 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EER24840.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain BAH PF01426.18 EER24840.1 - 0.0096 15.8 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_28 PF13521.6 EER24840.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EER24840.1 - 0.022 15.2 0.1 0.15 12.4 0.0 2.5 4 0 0 4 4 2 0 RNA helicase AAA_33 PF13671.6 EER24840.1 - 0.024 14.8 0.0 0.41 10.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EER24840.1 - 0.03 14.3 0.0 0.7 9.8 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_6 PF12774.7 EER24840.1 - 0.035 13.1 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 EER24840.1 - 0.055 13.2 0.1 0.15 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EER24840.1 - 0.085 12.4 0.0 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EER24840.1 - 0.096 12.6 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_32 PF13654.6 EER24840.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Nup54 PF13874.6 EER24841.1 - 6.7e-41 139.7 0.4 6.7e-41 139.7 0.4 2.2 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EER24841.1 - 5.1e-11 41.9 2.5 8.8e-11 41.2 2.5 1.4 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EER24841.1 - 5.6e-05 23.9 79.3 0.0002 22.1 31.9 3.3 1 1 2 3 3 3 2 Nucleoporin FG repeat region YscO-like PF16789.5 EER24841.1 - 0.012 15.6 5.2 0.021 14.9 5.2 1.2 1 0 0 1 1 1 0 YscO-like protein FapA PF03961.13 EER24841.1 - 2.8 6.5 5.7 2.8 6.5 4.7 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Med26 PF08711.11 EER24842.1 - 3.6e-10 39.7 0.0 8.3e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain MFS_1 PF07690.16 EER24843.1 - 7.7e-33 113.9 29.6 9.7e-33 113.5 29.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EER24843.1 - 0.0044 16.8 1.6 0.0048 16.7 0.2 1.7 2 0 0 2 2 2 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MFS_4 PF06779.14 EER24843.1 - 8.5 5.6 23.2 0.017 14.4 7.9 2.9 1 1 2 3 3 3 0 Uncharacterised MFS-type transporter YbfB MFS_1 PF07690.16 EER24844.1 - 1.4e-37 129.4 78.4 6.3e-32 110.9 48.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER24844.1 - 2.7e-07 29.8 14.3 2.7e-07 29.8 14.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EER24844.1 - 1.3e-05 24.0 10.4 1.3e-05 24.0 10.4 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein Folate_carrier PF01770.18 EER24844.1 - 0.0054 15.5 4.4 0.0054 15.5 4.4 2.0 2 0 0 2 2 2 1 Reduced folate carrier DIM1 PF02966.16 EER24845.1 - 3.8e-70 233.8 0.2 4.3e-70 233.7 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EER24845.1 - 0.0019 18.1 0.0 0.0024 17.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EER24845.1 - 0.2 12.0 1.3 0.33 11.3 1.3 1.4 1 1 0 1 1 1 0 Thioredoxin-like MFS_5 PF05631.14 EER24846.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM Peptidase_M19 PF01244.21 EER24847.1 - 1.1e-110 369.8 0.0 1.3e-110 369.5 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) 4HBT_2 PF13279.6 EER24848.1 - 3.6e-10 40.4 0.0 6.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.13 EER24849.1 - 2.2e-07 31.0 0.3 5e-07 29.9 0.3 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1847 PF08901.11 EER24849.1 - 0.061 13.0 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) DUF3008 PF11450.8 EER24849.1 - 0.33 11.2 2.6 2 8.6 1.7 2.2 2 0 0 2 2 2 0 Protein of unknwon function (DUF3008) RHD3 PF05879.12 EER24850.1 - 0 1036.0 0.1 0 1035.8 0.1 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EER24850.1 - 7.4e-07 28.7 0.1 1.4e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EER24850.1 - 4.9e-06 26.7 0.0 9.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EER24850.1 - 0.00023 21.2 0.0 0.00053 20.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EER24850.1 - 0.0024 18.1 0.1 0.0087 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF5442 PF17514.2 EER24850.1 - 0.0043 17.2 0.0 0.01 16.0 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5442) Zn_clus PF00172.18 EER24851.1 - 5.6e-05 23.2 10.3 0.00013 22.0 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EER24852.1 - 3.6e-44 151.1 47.5 3.6e-44 151.1 47.5 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER24852.1 - 3.9e-13 48.7 23.9 5.9e-13 48.1 23.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABM PF03992.16 EER24853.1 - 2.4e-06 27.5 3.5 0.0014 18.7 0.9 3.1 2 2 0 2 2 2 2 Antibiotic biosynthesis monooxygenase MBOAT_2 PF13813.6 EER24855.1 - 6e-20 71.3 6.4 6e-20 71.3 6.4 2.1 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Peptidase_S24 PF00717.23 EER24856.1 - 1.5e-07 31.2 0.0 3.1e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like GTP_EFTU PF00009.27 EER24858.1 - 4.8e-58 195.9 0.1 6.5e-58 195.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EER24858.1 - 6.7e-23 81.1 0.0 1.3e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EER24858.1 - 2.9e-17 62.8 1.2 6.8e-17 61.6 1.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EER24858.1 - 1.1e-05 25.4 0.1 2.3e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER24858.1 - 0.00045 20.2 0.0 0.0016 18.3 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 EER24858.1 - 0.0049 16.5 0.5 0.051 13.1 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EER24858.1 - 0.012 15.4 0.3 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EER24858.1 - 0.13 11.6 0.2 0.53 9.6 0.2 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IF3_C PF00707.22 EER24859.1 - 6.4e-10 38.9 0.3 1.1e-09 38.1 0.3 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 EER24859.1 - 3.3e-06 26.9 1.2 4.5e-06 26.4 0.5 1.5 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.16 EER24859.1 - 2.4e-05 24.5 0.0 5.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain CAP_N PF01213.19 EER24859.1 - 0.03 13.8 0.5 0.039 13.4 0.5 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GDA1_CD39 PF01150.17 EER24860.1 - 6.5e-104 347.9 0.0 8.2e-104 347.6 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.6 EER24861.1 - 1.6e-16 60.7 0.4 1.6e-16 60.7 0.4 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Macoilin PF09726.9 EER24861.1 - 0.75 8.3 5.6 0.87 8.1 5.6 1.1 1 0 0 1 1 1 0 Macoilin family IF4E PF01652.18 EER24862.1 - 4.7e-31 107.7 0.1 6.1e-31 107.4 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E OxoGdeHyase_C PF16870.5 EER24862.1 - 0.013 15.2 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase C-terminal COMPASS-Shg1 PF05205.12 EER24863.1 - 1.1e-25 90.2 0.1 3.2e-25 88.8 0.1 1.8 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Cation_efflux PF01545.21 EER24866.1 - 1.2e-12 48.0 14.0 1.6e-12 47.6 14.0 1.1 1 0 0 1 1 1 1 Cation efflux family zf-rbx1 PF12678.7 EER24867.1 - 9.6e-09 35.4 1.9 2.5e-08 34.1 1.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EER24867.1 - 1.5e-08 34.9 7.3 2.9e-08 33.9 2.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER24867.1 - 2.1e-07 30.6 7.1 5e-07 29.5 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER24867.1 - 6.8e-07 29.2 2.6 1.9e-06 27.7 2.6 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EER24867.1 - 3.3e-06 26.9 1.1 6.2e-06 26.0 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER24867.1 - 5.6e-05 22.9 4.3 6e-05 22.8 1.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EER24867.1 - 0.00014 21.7 0.9 0.00014 21.7 0.9 1.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EER24867.1 - 0.00025 20.7 8.5 0.0048 16.6 0.2 3.2 3 0 0 3 3 3 2 RING-like zinc finger Zn_ribbon_17 PF17120.5 EER24867.1 - 0.00062 19.3 0.6 0.0014 18.2 0.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EER24867.1 - 0.0009 19.2 8.1 0.004 17.1 3.6 3.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EER24867.1 - 0.0064 16.5 1.2 0.016 15.3 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 EER24867.1 - 0.016 13.1 0.9 0.024 12.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) RINGv PF12906.7 EER24867.1 - 3.9 7.7 7.4 0.23 11.6 1.8 1.8 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.8 EER24867.1 - 5.1 7.4 6.5 24 5.2 6.5 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain VSP PF03302.13 EER24868.1 - 0.15 10.8 0.1 0.19 10.6 0.1 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein GCV_H PF01597.19 EER24870.1 - 5.5e-42 142.5 2.7 6.6e-42 142.3 2.7 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EER24870.1 - 0.0061 16.5 0.2 0.0084 16.1 0.2 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EER24870.1 - 0.048 13.5 0.8 0.08 12.8 0.3 1.6 2 0 0 2 2 2 0 Biotin-requiring enzyme Ribosomal_S6 PF01250.17 EER24871.1 - 3.8e-24 84.8 0.0 5.1e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Dynamin_N PF00350.23 EER24872.1 - 4.8e-43 147.1 0.0 8.4e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EER24872.1 - 6.3e-10 38.7 0.0 1.1e-08 34.7 0.0 2.4 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 EER24872.1 - 7.3e-05 22.8 0.2 0.00034 20.7 0.0 2.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EER24872.1 - 0.029 14.1 0.5 0.2 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 EER24872.1 - 0.033 14.6 0.1 0.19 12.1 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain SRI PF08236.11 EER24872.1 - 0.036 14.3 2.3 0.066 13.4 0.9 2.1 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain AAA_21 PF13304.6 EER24872.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system GATase_4 PF13230.6 EER24873.1 - 5e-15 55.1 0.0 4.4e-13 48.8 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 EER24873.1 - 2.1e-08 34.4 0.0 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain PIG-Y PF15159.6 EER24874.1 - 3.9e-23 82.2 8.2 7.2e-23 81.3 8.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 EER24874.1 - 0.13 12.8 3.4 1.4 9.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF4470 PF14737.6 EER24875.1 - 1.3e-24 86.3 0.0 2.3e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EER24875.1 - 1.8e-09 37.5 11.1 3.5e-09 36.6 11.1 1.5 1 0 0 1 1 1 1 MYND finger tRNA-synt_His PF13393.6 EER24875.1 - 0.095 12.0 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase RRM_1 PF00076.22 EER24876.1 - 3.4e-61 203.0 0.0 3.3e-21 74.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER24876.1 - 7.2e-10 38.5 0.0 1.4e-05 24.7 0.0 3.1 2 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER24876.1 - 7.8e-09 35.3 0.0 0.0072 16.2 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EER24876.1 - 4.2e-05 23.5 0.1 1.3 9.1 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.10 EER24876.1 - 0.00061 19.8 0.0 0.35 11.0 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_8 PF11835.8 EER24876.1 - 0.00084 19.5 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain RRM_7 PF16367.5 EER24876.1 - 0.0011 19.1 0.0 0.99 9.6 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif Limkain-b1 PF11608.8 EER24876.1 - 0.033 14.3 0.1 8.8 6.5 0.0 3.2 3 0 0 3 3 3 0 Limkain b1 RRM_3 PF08777.11 EER24876.1 - 0.1 12.6 0.0 2.6 8.1 0.0 2.5 3 0 0 3 3 3 0 RNA binding motif SET_assoc PF11767.8 EER24876.1 - 0.17 11.5 0.0 25 4.6 0.0 2.5 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated GCD14 PF08704.10 EER24877.1 - 0.21 11.2 0.2 0.31 10.7 0.2 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Arrestin_C PF02752.22 EER24878.1 - 4.1e-11 43.5 0.0 9.6e-09 35.8 0.0 3.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EER24878.1 - 2.1e-07 31.1 0.0 0.00077 19.5 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain CFEM PF05730.11 EER24879.1 - 0.0055 16.8 6.9 0.0095 16.0 6.9 1.4 1 0 0 1 1 1 1 CFEM domain TMEM154 PF15102.6 EER24879.1 - 0.012 15.5 0.4 0.023 14.6 0.4 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4448 PF14610.6 EER24879.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) APG6_N PF17675.1 EER24879.1 - 0.026 15.0 0.9 0.046 14.3 0.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region UPAR_LY6_2 PF16975.5 EER24879.1 - 0.37 11.0 5.4 0.9 9.8 5.4 1.6 1 0 0 1 1 1 0 Ly6/PLAUR domain-containing protein 6, Lypd6 SKG6 PF08693.10 EER24879.1 - 0.41 10.1 2.8 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Stm1_N PF09598.10 EER24879.1 - 9 7.2 9.5 1.3 9.9 2.8 2.5 2 0 0 2 2 2 0 Stm1 Acetyltransf_10 PF13673.7 EER24882.1 - 1.8e-10 40.8 0.0 3.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER24882.1 - 2e-09 37.7 0.1 4.7e-09 36.5 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER24882.1 - 5.9e-07 29.7 0.0 8.5e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EER24882.1 - 0.00013 22.1 0.0 0.39 10.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER24882.1 - 0.00048 20.2 0.0 0.00092 19.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EER24882.1 - 0.044 13.8 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PRRSV_2b PF07069.11 EER24883.1 - 0.24 11.9 0.5 0.43 11.1 0.5 1.3 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b CAP59_mtransfer PF11735.8 EER24884.1 - 1.7e-73 247.3 0.0 2.2e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Chs7 PF12271.8 EER24885.1 - 4.5e-127 423.3 21.3 5.2e-127 423.1 21.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 EER24885.1 - 0.18 12.1 0.4 0.18 12.1 0.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF3382) O-ag_pol_Wzy PF14296.6 EER24885.1 - 0.75 8.4 20.8 0.36 9.4 10.8 2.2 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy DUF676 PF05057.14 EER24886.1 - 5.1e-07 29.4 0.0 9.8e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EER24886.1 - 0.00038 21.1 12.7 0.001 19.8 12.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EER24886.1 - 0.0031 17.2 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EER24886.1 - 0.031 13.5 0.0 0.057 12.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EER24886.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1459 PF07312.11 EER24886.1 - 5.3 7.3 8.2 4.2 7.7 3.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1459) Cyclin PF08613.11 EER24887.1 - 8.2e-13 49.0 0.0 1.2e-12 48.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EER24887.1 - 0.0079 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain 4HBT_3 PF13622.6 EER24888.1 - 3.1e-32 112.8 0.0 7e-32 111.6 0.0 1.6 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EER24888.1 - 1.9e-06 27.8 0.3 0.014 15.2 0.0 3.4 2 1 1 3 3 3 3 Acyl-CoA thioesterase WD40 PF00400.32 EER24888.1 - 0.094 13.6 0.0 0.31 12.0 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Ribosomal_L27A PF00828.19 EER24889.1 - 2.5e-31 109.0 1.9 3.9e-31 108.4 1.9 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HNH_2 PF13391.6 EER24890.1 - 3.8e-18 65.4 0.1 1.4e-17 63.6 0.2 1.8 2 0 0 2 2 2 1 HNH endonuclease HNH_4 PF13395.6 EER24890.1 - 0.093 12.7 0.1 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 HNH endonuclease Pkinase_fungal PF17667.1 EER24891.1 - 4.5e-28 98.1 0.0 9.1e-28 97.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase ERAP1_C PF11838.8 EER24891.1 - 0.0003 20.4 0.0 0.00051 19.7 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF2603 PF10788.9 EER24892.1 - 0.00077 19.5 3.2 0.00077 19.5 3.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2603) zf-CCHC PF00098.23 EER24892.1 - 0.0031 17.5 4.4 0.0064 16.5 4.4 1.5 1 0 0 1 1 1 1 Zinc knuckle PSI_integrin PF17205.3 EER24892.1 - 0.066 13.0 0.6 0.14 11.9 0.6 1.5 1 0 0 1 1 1 0 Integrin plexin domain DUF2996 PF11210.8 EER24892.1 - 0.07 13.6 1.4 0.097 13.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2996) GlutR_dimer PF00745.20 EER24892.1 - 0.14 12.6 1.2 0.39 11.2 0.4 2.1 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain zf-C2H2_10 PF16588.5 EER24892.1 - 2.3 8.0 5.1 4.9 7.0 5.1 1.6 1 0 0 1 1 1 0 C2H2 zinc-finger CVNH PF08881.10 EER24893.1 - 2.3e-13 50.7 0.2 2.7e-13 50.5 0.2 1.1 1 0 0 1 1 1 1 CVNH domain Pyr_redox_2 PF07992.14 EER24894.1 - 8.6e-53 179.5 0.0 1.1e-52 179.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER24894.1 - 1.1e-10 41.9 0.0 3.7e-09 37.0 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER24894.1 - 0.00046 19.5 0.1 0.57 9.4 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EER24894.1 - 2.2 8.8 4.7 9.5 6.7 0.0 3.5 3 1 0 3 3 3 0 Putative NAD(P)-binding Pkinase PF00069.25 EER24895.1 - 8.7e-46 156.4 0.0 1.3e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24895.1 - 1.5e-27 96.5 0.0 3.8e-21 75.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER24895.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SH3_1 PF00018.28 EER24896.1 - 3.9e-06 26.4 0.0 1.1e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER24896.1 - 0.0095 15.8 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 EER24896.1 - 0.04 13.7 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain PQ-loop PF04193.14 EER24897.1 - 6.1e-37 125.2 11.3 4.4e-19 68.0 0.7 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 EER24897.1 - 0.043 13.9 0.2 0.043 13.9 0.2 2.6 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Sporozoite_P67 PF05642.11 EER24897.1 - 1.5 6.8 3.9 2 6.4 3.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pkinase PF00069.25 EER24898.1 - 9.7e-05 21.9 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EER24898.1 - 0.0002 20.8 0.3 0.00038 19.9 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EER24898.1 - 0.00025 20.7 0.0 0.00063 19.4 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Radial_spoke_3 PF06098.11 EER24898.1 - 0.026 13.8 3.4 0.054 12.8 3.4 1.6 1 0 0 1 1 1 0 Radial spoke protein 3 APH PF01636.23 EER24898.1 - 0.065 13.1 0.1 0.065 13.1 0.1 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EER24898.1 - 0.11 11.8 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DDE_Tnp_IS66 PF03050.14 EER24898.1 - 5.2 6.4 6.3 7.1 6.0 4.2 1.9 2 0 0 2 2 2 0 Transposase IS66 family Aminotran_1_2 PF00155.21 EER24899.1 - 1.7e-62 211.7 0.0 2.5e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EER24899.1 - 0.0099 15.2 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Tmemb_18A PF09771.9 EER24899.1 - 0.029 14.8 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 AMP-binding PF00501.28 EER24900.1 - 2.9e-33 115.1 0.0 5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EER24900.1 - 1.7e-07 31.0 0.8 1.7e-07 31.0 0.8 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Peptidase_M16_C PF05193.21 EER24901.1 - 5.7e-48 163.3 0.0 1e-47 162.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EER24901.1 - 6.2e-41 139.8 0.0 9.5e-40 136.0 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) TRPM_tetra PF16519.5 EER24901.1 - 0.28 11.3 0.9 0.83 9.8 0.9 1.7 1 0 0 1 1 1 0 Tetramerisation domain of TRPM Abhydrolase_2 PF02230.16 EER24902.1 - 2e-25 89.9 0.0 9.2e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EER24902.1 - 8.3e-05 23.3 0.5 0.00014 22.6 0.5 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EER24902.1 - 0.0027 17.4 0.0 0.0063 16.2 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EER24902.1 - 0.027 13.9 0.4 0.062 12.8 0.0 1.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EER24902.1 - 0.056 12.7 0.3 3.4 6.9 0.0 2.5 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Tom22 PF04281.13 EER24903.1 - 1.4e-52 177.1 1.3 1.7e-52 176.9 1.3 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.6 EER24904.1 - 7e-44 149.4 0.0 2e-43 147.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) FANC_SAP PF18081.1 EER24904.1 - 0.75 10.0 3.4 5.3 7.3 3.2 2.4 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain GREB1 PF15782.5 EER24904.1 - 5.2 4.1 10.7 7.3 3.6 10.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4449 PF14613.6 EER24905.1 - 2.2e-66 223.0 2.4 2.2e-66 223.0 2.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) PTPLA PF04387.14 EER24906.1 - 1.5e-57 193.9 2.9 1.5e-57 193.9 2.9 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.9 EER24907.1 - 5.6e-15 56.0 0.6 1.3e-14 54.8 0.6 1.7 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 LSM PF01423.22 EER24908.1 - 1.7e-15 56.4 0.2 2.3e-15 56.0 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EER24908.1 - 0.092 12.9 0.1 0.16 12.1 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain PGP_phosphatase PF09419.10 EER24909.1 - 3.2e-45 153.8 0.0 3.9e-45 153.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EER24909.1 - 2.6e-08 33.8 0.0 5.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hyd_WA PF06462.12 EER24909.1 - 0.063 13.3 0.2 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Propeller Homeodomain PF00046.29 EER24910.1 - 3.9e-20 71.5 3.1 1e-19 70.1 3.1 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EER24910.1 - 0.00094 19.0 0.4 0.0023 17.8 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain Ndc1_Nup PF09531.10 EER24910.1 - 7.3 5.2 6.8 11 4.5 6.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PhoLip_ATPase_C PF16212.5 EER24911.1 - 1.6e-70 237.7 15.8 1.6e-70 237.7 15.8 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EER24911.1 - 2e-24 85.0 4.5 1.8e-23 82.0 0.8 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EER24911.1 - 5e-15 56.4 1.1 8.9e-09 35.9 0.7 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EER24911.1 - 4.3e-13 49.2 0.0 6.8e-12 45.3 0.0 2.6 2 1 1 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EER24911.1 - 1.7e-07 31.0 0.0 1.7e-07 31.0 0.0 2.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EER24911.1 - 0.00041 20.2 0.3 0.0014 18.4 0.1 1.9 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EER24911.1 - 0.033 14.3 0.5 0.46 10.5 0.2 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SART-1 PF03343.13 EER24912.1 - 2.8e-195 650.6 67.0 3.1e-195 650.4 67.0 1.0 1 0 0 1 1 1 1 SART-1 family SIMPL PF04402.14 EER24912.1 - 9.8e-05 22.9 2.2 9.8e-05 22.9 2.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF541) CH_2 PF06294.11 EER24912.1 - 0.099 12.8 2.4 0.29 11.3 0.3 2.4 2 0 0 2 2 2 0 CH-like domain in sperm protein PTH2 PF01981.16 EER24913.1 - 5.8e-42 142.7 0.0 8.1e-42 142.2 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Cation_efflux PF01545.21 EER24915.1 - 2.9e-26 92.5 10.2 3.6e-26 92.1 10.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EER24915.1 - 4e-08 33.3 0.1 6.9e-08 32.5 0.1 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF3169 PF11368.8 EER24915.1 - 0.045 13.3 0.2 0.045 13.3 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) DUF423 PF04241.15 EER24915.1 - 2.1 8.6 5.2 2.3 8.5 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF423) Zip PF02535.22 EER24916.1 - 1.2e-51 175.9 0.2 1.7e-51 175.4 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter HMGL-like PF00682.19 EER24917.1 - 1.4e-79 267.4 0.5 1.9e-79 266.9 0.5 1.2 1 0 0 1 1 1 1 HMGL-like Endonuc-BglII PF09195.11 EER24917.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease BglII Hpt PF01627.23 EER24918.1 - 7.5e-12 45.3 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Zn_clus PF00172.18 EER24919.1 - 5.9e-08 32.7 10.7 5.9e-08 32.7 10.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 EER24920.1 - 3.1e-53 181.2 0.0 3.7e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.17 EER24921.1 - 5.5e-52 176.4 0.4 1.4e-51 175.0 0.1 1.8 2 0 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 EER24921.1 - 2.7e-12 46.6 0.5 4.6e-09 36.0 0.1 2.4 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Tic110 PF16940.5 EER24921.1 - 0.048 12.1 0.1 0.079 11.4 0.1 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter ANTAR PF03861.14 EER24921.1 - 0.087 12.7 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 ANTAR domain DUF3425 PF11905.8 EER24922.1 - 1.3e-33 115.6 0.0 2.1e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) ABC2_membrane PF01061.24 EER24923.1 - 2.8e-87 291.5 50.3 7.9e-47 159.4 22.7 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 EER24923.1 - 3.7e-39 132.5 10.3 8.9e-35 118.5 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 EER24923.1 - 1.3e-36 126.1 0.0 1.1e-16 61.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 EER24923.1 - 4.2e-19 68.9 0.2 1.2e-18 67.4 0.1 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EER24923.1 - 1.2e-05 25.8 0.2 0.0077 16.6 0.1 2.9 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EER24923.1 - 1.4e-05 24.4 49.8 0.00053 19.2 19.6 3.4 2 2 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EER24923.1 - 1.5e-05 25.0 0.1 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EER24923.1 - 2.2e-05 24.1 0.2 0.00095 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EER24923.1 - 0.00011 22.4 0.1 0.018 15.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EER24923.1 - 0.00036 20.0 0.0 0.2 11.1 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EER24923.1 - 0.00038 21.0 0.0 0.045 14.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EER24923.1 - 0.00058 19.5 1.5 0.036 13.8 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EER24923.1 - 0.00061 19.7 0.0 0.64 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 EER24923.1 - 0.019 15.4 0.2 9 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EER24923.1 - 0.036 14.5 0.9 6 7.3 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EER24923.1 - 0.037 13.6 0.9 0.24 11.0 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EER24923.1 - 0.067 13.1 1.1 5.8 6.8 0.5 2.9 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 EER24923.1 - 0.08 13.2 1.4 2.6 8.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EER24923.1 - 0.11 12.2 1.4 2.8 7.6 0.4 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EER24923.1 - 0.12 12.3 0.0 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain adh_short PF00106.25 EER24924.1 - 2.5e-06 27.1 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER24924.1 - 0.00048 20.1 0.0 0.0008 19.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EER24924.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF4448 PF14610.6 EER24925.1 - 7.1e-35 120.5 0.0 9.3e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3602 PF12223.8 EER24926.1 - 0.25 12.0 4.7 0.48 11.0 1.4 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3602) HAD_2 PF13419.6 EER24927.1 - 5.5e-16 59.2 0.0 1e-15 58.3 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EER24927.1 - 4.6e-14 53.2 0.0 2.9e-10 40.8 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER24927.1 - 9.8e-07 28.8 0.1 4.2e-06 26.7 0.1 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 EER24927.1 - 0.0013 18.4 0.0 0.17 11.5 0.0 2.5 2 1 0 2 2 2 2 Mitochondrial PGP phosphatase HAD PF12710.7 EER24927.1 - 0.0076 16.7 0.0 0.028 14.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-CCHC_6 PF15288.6 EER24928.1 - 0.52 10.2 14.8 1.4 8.8 0.4 3.5 1 1 2 3 3 3 0 Zinc knuckle zinc_ribbon_6 PF14599.6 EER24928.1 - 3.3 7.8 8.9 0.27 11.3 2.3 2.5 2 0 0 2 2 2 0 Zinc-ribbon ORMDL PF04061.14 EER24929.1 - 1.6e-58 196.4 4.1 1.8e-58 196.2 4.1 1.0 1 0 0 1 1 1 1 ORMDL family CH PF00307.31 EER24931.1 - 3.7e-14 52.8 0.0 6.2e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4266 PF14086.6 EER24931.1 - 0.87 10.6 3.5 1.5 9.8 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) Peptidase_S8 PF00082.22 EER24932.1 - 1.3e-29 103.4 15.1 3.5e-29 102.0 15.1 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER24932.1 - 2.3e-18 66.6 0.0 3.9e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3553 PF12073.8 EER24932.1 - 0.058 13.1 0.1 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Med1 PF10744.9 EER24933.1 - 3.4e-131 438.1 0.0 4.5e-131 437.7 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 PNRC PF15365.6 EER24933.1 - 0.038 13.8 0.8 0.18 11.7 0.8 2.3 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif p450 PF00067.22 EER24934.1 - 2.8e-101 339.6 0.0 3.2e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TrwC PF08751.11 EER24934.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 TrwC relaxase SRAP PF02586.14 EER24935.1 - 5e-82 274.7 0.0 6.6e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_12 PF13424.6 EER24936.1 - 2.7e-07 30.8 6.6 0.0013 19.0 0.1 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EER24936.1 - 6.7e-05 22.7 10.4 0.00014 21.7 0.2 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER24936.1 - 0.00033 20.3 5.4 0.0045 16.8 0.2 4.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EER24936.1 - 0.0054 16.9 10.4 0.75 10.2 0.3 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EER24936.1 - 0.0064 15.9 0.5 0.3 10.4 0.0 3.1 3 1 0 3 3 3 1 MalT-like TPR region TPR_7 PF13176.6 EER24936.1 - 0.012 15.6 4.7 6.8 7.0 0.0 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 EER24936.1 - 0.016 15.0 8.1 1.2 9.1 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EER24936.1 - 0.084 13.6 1.2 3.4 8.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EER24936.1 - 0.11 13.3 1.6 37 5.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 EER24937.1 - 1.9e-44 148.7 22.9 1.3e-09 38.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER24937.1 - 2.2e-08 34.3 0.9 0.19 12.1 0.0 4.5 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER24937.1 - 4.1e-05 22.4 8.9 0.097 11.3 0.2 4.7 2 1 3 5 5 5 3 Nucleoporin Nup120/160 PD40 PF07676.12 EER24937.1 - 0.015 15.3 0.2 20 5.3 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EER24937.1 - 0.018 13.6 0.0 1.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 EER24937.1 - 0.023 13.7 0.1 7.5 5.4 0.0 3.6 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EER24937.1 - 0.068 12.5 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Sdh5 PF03937.16 EER24938.1 - 3.5e-25 87.7 0.1 1.4e-24 85.8 0.1 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase AXIN1_TNKS_BD PF16646.5 EER24938.1 - 0.015 16.2 1.8 0.64 11.0 0.1 2.5 2 0 0 2 2 2 0 Axin-1 tankyrase binding domain EMP24_GP25L PF01105.24 EER24939.1 - 7.9e-40 136.7 0.0 8.8e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Usher_TcfC PF17271.2 EER24939.1 - 0.12 11.1 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 TcfC Usher-like barrel domain BTB PF00651.31 EER24940.1 - 0.0066 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BSP_II PF05432.11 EER24941.1 - 0.0012 18.6 1.8 0.0012 18.6 1.8 1.9 2 0 0 2 2 2 1 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.19 EER24941.1 - 0.52 10.9 6.4 0.1 13.2 1.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAM176 PF14851.6 EER24941.1 - 2.2 7.9 5.5 0.38 10.4 1.0 2.0 2 0 0 2 2 2 0 FAM176 family AAA_8 PF12780.7 EER24942.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 NDUFA12 PF05071.16 EER24944.1 - 7e-11 42.8 9.2 2.8e-10 40.9 9.2 2.1 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Gln-synt_C PF00120.24 EER24946.1 - 1.9e-16 60.0 0.0 2.3e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EER24946.1 - 3.1e-15 55.6 0.0 5.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 EER24947.1 - 3.7e-37 128.1 45.1 1.6e-31 109.5 27.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EER24947.1 - 0.0023 17.7 1.3 0.0045 16.7 1.3 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MASE2 PF05230.11 EER24947.1 - 0.36 10.9 7.0 0.32 11.1 3.6 2.5 2 0 0 2 2 2 0 MASE2 domain PRA1 PF03208.19 EER24947.1 - 6.3 6.4 9.3 5.8 6.5 4.3 2.6 2 0 0 2 2 2 0 PRA1 family protein DAO PF01266.24 EER24948.1 - 2.6e-36 125.9 0.3 3.1e-36 125.7 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER24948.1 - 0.00096 19.3 0.1 0.0024 18.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EER24948.1 - 0.0061 17.1 0.0 0.014 15.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER24948.1 - 0.025 13.8 2.4 0.038 13.2 0.1 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER24948.1 - 0.048 12.9 0.2 0.048 12.9 0.2 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_7 PF13241.6 EER24948.1 - 0.088 13.3 0.0 0.13 12.7 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EER24948.1 - 0.1 12.9 0.5 0.5 10.6 0.2 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EER24948.1 - 0.11 12.0 0.3 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.14 EER24948.1 - 0.24 10.2 0.3 0.57 9.0 0.2 1.6 2 0 0 2 2 2 0 Tryptophan halogenase OTU PF02338.19 EER24949.1 - 2.4e-12 47.5 0.0 8.6e-12 45.7 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 EER24949.1 - 0.00041 20.0 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain AF-4 PF05110.13 EER24949.1 - 0.023 12.8 1.7 0.041 12.0 1.7 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PBP1_TM PF14812.6 EER24949.1 - 0.13 12.6 5.4 0.35 11.3 0.8 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thioredoxin PF00085.20 EER24950.1 - 1.2e-27 95.9 0.2 1.4e-27 95.6 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EER24950.1 - 3.5e-08 33.9 0.4 7.4e-08 32.8 0.4 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EER24950.1 - 1.7e-07 31.1 0.1 1.8e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EER24950.1 - 6e-07 29.7 0.0 3.9e-06 27.1 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EER24950.1 - 4e-05 23.4 0.7 0.00035 20.3 0.8 2.0 1 1 0 1 1 1 1 Redoxin OST3_OST6 PF04756.13 EER24950.1 - 0.00011 21.7 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family TraF PF13728.6 EER24950.1 - 0.00076 19.4 0.0 0.00085 19.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.21 EER24950.1 - 0.00083 19.3 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 EER24950.1 - 0.0046 17.1 0.4 0.011 15.9 0.4 1.8 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 EER24950.1 - 0.008 16.4 0.3 0.013 15.7 0.3 1.4 1 0 0 1 1 1 1 Glutaredoxin HyaE PF07449.11 EER24950.1 - 0.011 15.6 0.1 0.035 14.1 0.0 1.7 1 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.6 EER24950.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin TyeA PF09059.10 EER24950.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 TyeA NAD2 PF18782.1 EER24950.1 - 0.21 11.7 0.1 0.26 11.4 0.1 1.1 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Peptidase_M19 PF01244.21 EER24951.1 - 2.8e-106 355.3 0.0 3.4e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Toxin_16 PF07945.11 EER24952.1 - 0.087 12.7 4.8 0.22 11.4 4.8 1.6 1 0 0 1 1 1 0 Janus-atracotoxin AA_permease PF00324.21 EER24954.1 - 1.5e-130 436.0 51.8 1.8e-130 435.8 51.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER24954.1 - 1.7e-26 93.1 57.1 2.1e-26 92.7 57.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1681 PF07933.14 EER24955.1 - 2.7e-56 189.4 0.0 3.5e-56 189.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) SMN PF06003.12 EER24955.1 - 1 8.5 4.5 1.6 7.9 4.5 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) IF-2B PF01008.17 EER24956.1 - 1.7e-45 155.4 0.0 4.2e-45 154.1 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Nuf2 PF03800.14 EER24957.1 - 2.4e-40 137.8 0.9 5.3e-40 136.8 0.1 2.0 2 0 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EER24957.1 - 3.6e-34 117.3 18.4 3.6e-34 117.3 18.4 3.4 2 2 1 3 3 3 1 Designed helical repeat protein 10 domain Clr5 PF14420.6 EER24957.1 - 0.63 10.3 6.7 4.6 7.5 0.6 2.9 3 0 0 3 3 3 0 Clr5 domain Spc7 PF08317.11 EER24957.1 - 1.5 7.6 47.5 0.3 9.9 11.7 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Adaptin_N PF01602.20 EER24958.1 - 1e-104 351.0 0.2 1.2e-104 350.7 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EER24958.1 - 9.5e-18 64.8 0.2 1.1e-14 54.8 0.0 3.5 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EER24958.1 - 7.1e-11 42.4 1.0 0.00017 21.9 0.0 4.7 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 EER24958.1 - 1.5e-07 31.1 0.1 0.12 12.7 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat Cohesin_HEAT PF12765.7 EER24958.1 - 0.0017 18.6 0.1 0.22 11.9 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion VHS PF00790.19 EER24958.1 - 0.0085 15.9 0.3 32 4.3 0.0 4.5 4 0 0 4 4 4 0 VHS domain MOR2-PAG1_N PF14222.6 EER24958.1 - 0.01 14.8 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal Cnd3 PF12719.7 EER24958.1 - 0.11 11.7 0.6 0.83 8.8 0.1 2.5 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain DUF2052 PF09747.9 EER24958.1 - 0.16 12.1 18.0 0.56 10.3 14.8 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) SAPS PF04499.15 EER24958.1 - 1.8 7.3 9.2 3.7 6.2 9.2 1.5 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein SpoIIIAH PF12685.7 EER24958.1 - 5 6.9 13.9 24 4.7 11.6 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein SDA1 PF05285.12 EER24958.1 - 6.7 6.0 29.2 0.23 10.8 22.1 1.9 2 0 0 2 2 2 0 SDA1 RR_TM4-6 PF06459.12 EER24958.1 - 9.9 5.9 15.5 30 4.3 11.8 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Ost5 PF05251.12 EER24959.1 - 1.2 9.5 8.1 0.49 10.7 3.5 2.6 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Metallophos PF00149.28 EER24961.1 - 7.6e-38 131.1 0.4 1.1e-37 130.6 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EER24961.1 - 0.056 13.9 0.2 0.18 12.3 0.2 1.9 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Rho_GDI PF02115.17 EER24962.1 - 6.4e-66 221.8 0.3 7.6e-66 221.6 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.13 EER24963.1 - 0.00074 19.3 0.0 0.0096 15.8 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain GTP1_OBG PF01018.22 EER24963.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 GTP1/OBG CLP1_N PF16573.5 EER24964.1 - 2.1e-32 111.2 0.0 4.1e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 EER24964.1 - 8e-31 107.3 0.0 8.9e-30 103.9 0.0 2.3 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EER24964.1 - 5.3e-25 88.1 0.0 3e-24 85.7 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 EER24964.1 - 8e-05 22.5 0.0 0.00025 20.9 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EER24964.1 - 0.0013 18.8 0.0 0.0071 16.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EER24964.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EER24964.1 - 0.078 13.5 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_35 PF14516.6 EER24964.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain SRPRB PF09439.10 EER24964.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ADH_zinc_N PF00107.26 EER24966.1 - 1.5e-25 89.7 0.1 2.6e-25 88.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER24966.1 - 1.4e-22 81.1 0.0 2.3e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER24966.1 - 1.8e-08 34.2 0.0 1.1e-07 31.7 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EER24966.1 - 0.042 13.7 0.1 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Arb1 PF09692.10 EER24967.1 - 8.3e-139 463.2 0.0 1e-138 462.9 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.16 EER24968.1 - 6.2e-57 192.7 0.0 9.3e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.21 EER24969.1 - 8.6e-26 89.6 0.0 1.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.13 EER24970.1 - 1e-22 79.8 0.1 1.7e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit TFIIA PF03153.13 EER24970.1 - 8 6.3 22.3 14 5.6 22.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRF PF08558.10 EER24971.1 - 5.5e-81 271.7 0.0 8.7e-81 271.0 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EER24971.1 - 0.00065 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain His_Phos_2 PF00328.22 EER24972.1 - 5.1e-05 22.8 0.0 0.00014 21.3 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) SUR7 PF06687.12 EER24972.1 - 0.069 12.8 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 SUR7/PalI family Glycophorin_A PF01102.18 EER24972.1 - 0.087 13.1 0.0 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 Glycophorin A MFS_1 PF07690.16 EER24974.1 - 1.6e-32 112.8 53.7 3.4e-30 105.2 56.4 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4006 PF13179.6 EER24974.1 - 0.064 13.2 0.0 0.26 11.2 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF4006) DUF2140 PF09911.9 EER24974.1 - 0.39 10.2 1.3 8.8 5.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Pkinase PF00069.25 EER24975.1 - 1.8e-74 250.4 0.0 2.6e-74 249.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER24975.1 - 2.2e-30 105.8 0.0 2.8e-22 79.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EER24975.1 - 2.3e-06 27.2 0.0 1.2 8.4 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EER24975.1 - 0.034 12.9 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EER24975.1 - 0.043 13.2 0.0 0.071 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Olduvai PF06758.13 EER24975.1 - 0.062 13.6 0.1 0.2 12.0 0.1 1.9 1 0 0 1 1 1 0 Olduvai domain APH PF01636.23 EER24975.1 - 0.08 12.8 0.0 2.9 7.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S5_C PF03719.15 EER24976.1 - 2.3e-25 87.8 0.1 1.2e-23 82.3 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EER24976.1 - 2.3e-17 62.7 0.9 4.6e-17 61.8 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.11 EER24977.1 - 4.8e-16 58.7 0.0 3.1e-14 52.7 0.0 2.4 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EER24977.1 - 2.7e-06 27.2 0.0 5.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER24977.1 - 1.9e-05 25.3 0.0 4.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EER24977.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EER24977.1 - 0.0036 17.9 0.0 0.01 16.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER24977.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 EER24977.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltrans_SAM PF10672.9 EER24977.1 - 0.037 13.2 0.0 0.063 12.4 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_4 PF02390.17 EER24977.1 - 0.084 12.3 0.0 0.87 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Actin PF00022.19 EER24978.1 - 6.4e-88 295.1 0.0 1.1e-53 182.3 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 EER24978.1 - 0.0045 17.4 0.0 0.007 16.8 0.0 1.4 1 0 0 1 1 1 1 Cell division protein FtsA MreB_Mbl PF06723.13 EER24978.1 - 0.014 14.2 0.0 0.54 9.0 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 EER24979.1 - 6.3e-43 147.0 5.6 1.2e-29 103.3 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 EER24980.1 - 1.2e-116 389.1 0.0 1.4e-116 388.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.8 EER24981.1 - 7.8e-41 139.6 1.3 8.5e-40 136.2 0.5 3.0 3 0 0 3 3 3 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EER24981.1 - 0.0027 17.7 11.1 5.4 7.2 0.0 6.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat TPR_15 PF13429.6 EER24981.1 - 0.026 13.8 0.6 0.06 12.6 0.6 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Atx10homo_assoc PF09759.9 EER24981.1 - 0.064 13.3 0.0 25 5.0 0.0 3.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain GDPD PF03009.17 EER24982.1 - 1.9e-68 231.0 0.0 4e-68 230.0 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.6 EER24982.1 - 1.7e-27 95.4 0.9 5e-10 39.7 0.1 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER24982.1 - 8.9e-27 93.5 0.0 6.6e-10 39.4 0.3 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.19 EER24982.1 - 7.7e-21 75.4 8.3 1.4e-11 45.0 0.3 3.5 1 1 2 3 3 3 3 SPX domain Ank_3 PF13606.6 EER24982.1 - 3.6e-16 57.6 2.9 0.0034 17.7 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 EER24982.1 - 3.5e-13 49.4 8.2 0.002 18.5 0.0 6.5 6 1 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EER24982.1 - 5.3e-13 48.9 0.4 0.00052 20.2 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (many copies) PRMT5_TIM PF17285.2 EER24983.1 - 5.7e-70 235.4 0.0 1.1e-69 234.5 0.0 1.5 2 0 0 2 2 2 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EER24983.1 - 1.5e-65 220.3 0.0 2.2e-65 219.7 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EER24983.1 - 2.4e-56 190.4 0.0 6.2e-56 189.1 0.0 1.7 1 0 0 1 1 1 1 PRMT5 oligomerisation domain OB_NTP_bind PF07717.16 EER24984.1 - 3.7e-20 72.1 0.0 1.1e-19 70.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EER24984.1 - 2.1e-19 69.8 0.0 5.1e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EER24984.1 - 1e-09 38.7 0.0 2.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EER24984.1 - 3.9e-06 26.8 0.1 7.8e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EER24984.1 - 7.2e-06 26.3 0.1 4.2e-05 23.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain Flavi_DEAD PF07652.14 EER24984.1 - 0.0013 18.8 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.22 EER24984.1 - 0.0014 18.3 0.1 0.0041 16.8 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 EER24984.1 - 0.0014 18.9 0.1 0.003 17.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EER24984.1 - 0.0082 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EER24984.1 - 0.014 15.9 0.0 0.03 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EER24984.1 - 0.059 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EER24984.1 - 0.06 12.9 0.0 0.27 10.7 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EER24984.1 - 0.16 11.7 0.1 5 6.8 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 EER24984.1 - 0.21 12.1 0.1 0.77 10.3 0.1 2.1 1 1 0 1 1 1 0 ABC transporter EF-hand_6 PF13405.6 EER24986.1 - 1.1e-08 34.3 0.0 0.0042 16.9 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EER24986.1 - 0.0003 20.1 0.0 0.0012 18.3 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EER24986.1 - 0.00085 19.7 0.3 0.003 18.0 0.1 2.0 2 1 0 2 2 2 1 EF-hand domain pair Skp1 PF01466.19 EER24986.1 - 0.53 10.5 2.1 9.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Met_10 PF02475.16 EER24987.1 - 0.00015 21.6 0.0 0.00032 20.5 0.0 1.5 1 1 0 1 1 1 1 Met-10+ like-protein Vinculin PF01044.19 EER24987.1 - 0.11 10.7 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 Vinculin family MFS_1 PF07690.16 EER24988.1 - 2.6e-21 75.9 76.6 4.8e-19 68.5 41.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ANAPC4_WD40 PF12894.7 EER24989.1 - 5e-05 23.5 0.0 0.39 11.0 0.0 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EER24989.1 - 0.00036 20.3 0.1 0.65 9.7 0.0 3.2 3 0 0 3 3 3 2 TUP1-like enhancer of split CNH PF00780.22 EER24989.1 - 0.0004 20.1 0.3 1 8.9 0.2 3.1 2 1 0 2 2 2 2 CNH domain Coatomer_WDAD PF04053.14 EER24989.1 - 0.0012 17.9 0.0 0.0028 16.8 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EER24989.1 - 0.013 16.4 0.0 3.1 8.8 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat MMS1_N PF10433.9 EER24989.1 - 0.027 13.1 0.1 1.4 7.4 0.0 2.7 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cupin_8 PF13621.6 EER24990.1 - 2.9e-43 148.4 0.0 5e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 EER24990.1 - 3.6e-17 62.9 0.0 5.9e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EER24990.1 - 1.4e-13 50.6 8.7 2.5e-05 24.2 0.0 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EER24990.1 - 4e-09 36.3 1.3 0.023 14.7 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Cupin_4 PF08007.12 EER24990.1 - 5.7e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_3 PF13415.6 EER24990.1 - 1.2e-05 25.5 3.8 0.0023 18.2 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EER24990.1 - 0.011 16.0 9.5 0.49 10.8 0.1 4.9 4 1 1 5 5 5 0 Kelch motif Kelch_1 PF01344.25 EER24990.1 - 0.48 10.0 1.9 22 4.8 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.15 EER24990.1 - 1 9.5 5.9 28 4.9 0.0 3.9 4 0 0 4 4 4 0 Kelch motif DSPc PF00782.20 EER24991.1 - 4.6e-27 94.4 0.0 4.4e-19 68.6 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EER24991.1 - 0.0008 19.0 0.0 0.01 15.4 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EER24991.1 - 0.01 16.0 0.0 0.049 13.7 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate Mlh1_C PF16413.5 EER24992.1 - 5.2e-103 344.1 0.0 7.2e-103 343.6 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EER24992.1 - 3.7e-35 120.2 0.1 4.1e-34 116.8 0.0 2.4 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EER24992.1 - 2.6e-13 50.0 0.1 6.4e-13 48.7 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EER24992.1 - 1.9e-06 28.3 0.0 4.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RPN1_RPN2_N PF17781.1 EER24994.1 - 7.7e-121 403.2 5.7 1.3e-120 402.5 5.7 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EER24994.1 - 2.7e-29 101.0 0.0 4.8e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EER24994.1 - 2.6e-20 71.8 14.4 4.5e-05 23.7 0.1 8.7 9 0 0 9 9 9 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EER24994.1 - 0.00091 19.6 4.5 9 6.8 0.0 5.2 5 2 2 7 7 7 3 HEAT repeats T2SSF PF00482.23 EER24994.1 - 0.025 14.6 1.1 7.9 6.5 0.0 3.5 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F GST_C PF00043.25 EER24994.1 - 0.31 11.3 1.9 21 5.4 0.9 3.3 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain RIO1 PF01163.22 EER24995.1 - 2.2e-42 144.8 0.6 7.8e-30 103.9 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 EER24995.1 - 1.4e-32 111.7 0.0 2.7e-32 110.8 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EER24995.1 - 2.5e-09 37.4 0.1 0.00012 22.1 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EER24995.1 - 3.8e-08 32.9 0.1 3.7e-06 26.5 0.1 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L23 PF00276.20 EER24996.1 - 5e-11 42.8 0.0 7.8e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Lon_C PF05362.13 EER24997.1 - 7.5e-70 234.6 0.7 2.1e-69 233.2 0.4 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EER24997.1 - 1.3e-26 93.7 0.0 3.3e-26 92.4 0.0 1.7 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EER24997.1 - 1.7e-23 83.5 0.0 6.9e-23 81.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 EER24997.1 - 3e-07 30.3 0.1 1.1e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EER24997.1 - 3.1e-07 30.5 0.0 8.5e-07 29.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EER24997.1 - 7.6e-07 29.7 0.0 2.8e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EER24997.1 - 3.9e-05 23.4 0.1 0.00021 21.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EER24997.1 - 0.00034 20.5 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EER24997.1 - 0.00038 20.2 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EER24997.1 - 0.0005 20.4 0.1 0.0085 16.4 0.0 3.0 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.13 EER24997.1 - 0.0025 17.1 0.0 0.0057 15.9 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EER24997.1 - 0.0053 16.9 0.0 0.019 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EER24997.1 - 0.0059 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Birna_VP4 PF01768.16 EER24997.1 - 0.0097 15.7 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 1 Birnavirus VP4 protein Rad17 PF03215.15 EER24997.1 - 0.013 15.4 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain TniB PF05621.11 EER24997.1 - 0.016 14.6 0.0 0.049 13.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein RNA_helicase PF00910.22 EER24997.1 - 0.02 15.3 0.0 0.06 13.7 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.21 EER24997.1 - 0.023 14.1 0.1 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EER24997.1 - 0.028 14.5 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EER24997.1 - 0.033 14.7 0.1 0.086 13.4 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.11 EER24997.1 - 0.041 12.8 0.1 0.21 10.4 0.1 1.9 2 0 0 2 2 2 0 PrkA AAA domain ABC_tran PF00005.27 EER24997.1 - 0.05 14.1 1.0 0.29 11.6 0.0 2.6 3 0 0 3 3 2 0 ABC transporter NACHT PF05729.12 EER24997.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 EER24997.1 - 0.05 12.9 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_7 PF12775.7 EER24997.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EER24997.1 - 0.076 12.5 0.0 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EER24997.1 - 0.085 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 EER24997.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EER24997.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EER24997.1 - 0.12 12.8 0.1 0.31 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain TRAPPC10 PF12584.8 EER24997.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 AAA_30 PF13604.6 EER24997.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EER24997.1 - 0.18 12.3 0.0 0.18 12.3 0.0 2.7 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 EER24997.1 - 0.68 9.7 4.2 0.33 10.7 0.2 2.0 1 1 1 2 2 2 0 AAA domain Porphobil_deam PF01379.20 EER24998.1 - 3.6e-71 238.9 0.5 6.4e-71 238.1 0.1 1.5 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EER24998.1 - 3.2e-17 62.7 0.1 5.3e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lipase_GDSL_2 PF13472.6 EER24999.1 - 3e-15 57.1 0.0 2.2e-13 51.0 0.0 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EER24999.1 - 4.8e-13 49.5 0.0 7.5e-13 48.9 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TAP42 PF04177.12 EER25000.1 - 1e-106 356.7 2.6 1.1e-106 356.5 2.6 1.0 1 0 0 1 1 1 1 TAP42-like family Ribonuclease_3 PF00636.26 EER25001.1 - 1.7e-45 154.0 0.0 2.7e-22 79.4 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EER25001.1 - 2e-27 95.9 0.0 1.1e-14 54.7 0.0 3.5 2 1 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EER25001.1 - 8.1e-22 77.2 2.4 1.4e-20 73.2 0.1 3.5 4 0 0 4 4 4 1 Dicer dimerisation domain Helicase_C PF00271.31 EER25001.1 - 1.1e-16 61.1 0.1 3.8e-16 59.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER25001.1 - 1.2e-13 51.4 0.4 2.7e-13 50.3 0.4 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EER25001.1 - 2.1e-10 40.7 0.0 4.2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 EER25001.1 - 6.2e-06 26.8 0.1 0.082 13.6 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif DHC_N1 PF08385.12 EER25002.1 - 1.1e-127 427.1 6.2 1.1e-127 427.1 6.2 4.9 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 EER25002.1 - 2e-124 414.8 0.0 2.1e-123 411.5 0.0 2.8 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EER25002.1 - 1.1e-116 390.2 6.0 1.1e-116 390.2 6.0 4.7 6 1 1 7 7 6 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EER25002.1 - 1.1e-74 250.3 1.5 1.1e-74 250.3 1.5 4.3 4 1 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EER25002.1 - 7e-67 225.5 0.0 5.8e-66 222.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EER25002.1 - 2.5e-44 150.9 0.0 1.5e-36 125.6 0.0 5.6 5 0 0 5 5 5 2 P-loop containing dynein motor region MT PF12777.7 EER25002.1 - 9.5e-39 133.4 7.2 1.9e-38 132.4 7.2 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EER25002.1 - 2.9e-32 111.6 0.7 1e-10 41.7 0.0 6.7 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EER25002.1 - 1.5e-31 108.9 1.2 6.5e-27 94.0 0.0 4.8 5 0 0 5 5 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EER25002.1 - 1.2e-27 96.8 0.0 3.2e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 EER25002.1 - 1e-20 74.1 0.4 1.5e-18 67.1 0.0 3.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EER25002.1 - 1.9e-14 54.2 0.0 0.00046 20.6 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EER25002.1 - 6.9e-14 52.3 8.4 0.0074 16.6 0.0 7.1 7 0 0 7 7 5 3 AAA domain AAA_33 PF13671.6 EER25002.1 - 2.9e-10 40.5 2.5 0.061 13.5 0.0 5.8 5 0 0 5 5 4 3 AAA domain AAA_16 PF13191.6 EER25002.1 - 4.2e-10 40.3 1.6 1.2 9.5 0.0 7.6 7 0 0 7 7 6 2 AAA ATPase domain AAA_18 PF13238.6 EER25002.1 - 4.3e-10 40.3 0.4 0.059 13.9 0.0 5.6 5 0 0 5 5 4 2 AAA domain T2SSE PF00437.20 EER25002.1 - 2.2e-06 26.9 0.0 0.035 13.2 0.0 3.8 3 0 0 3 3 3 1 Type II/IV secretion system protein ABC_tran PF00005.27 EER25002.1 - 3.4e-06 27.6 1.5 0.4 11.2 0.0 5.6 5 0 0 5 5 4 2 ABC transporter AAA_lid_1 PF17857.1 EER25002.1 - 2.9e-05 24.2 0.3 0.0015 18.7 0.0 3.5 3 0 0 3 3 3 1 AAA+ lid domain Mg_chelatase PF01078.21 EER25002.1 - 7.3e-05 22.3 0.9 0.66 9.3 0.0 4.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EER25002.1 - 9.7e-05 22.0 0.2 2.3 8.0 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EER25002.1 - 0.00022 20.6 0.0 1.7 7.9 0.0 4.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EER25002.1 - 0.00071 19.3 0.5 39 3.9 0.0 4.8 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 EER25002.1 - 0.0017 18.0 0.0 0.32 10.5 0.0 3.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EER25002.1 - 0.0031 17.9 0.2 17 5.9 0.0 5.1 5 0 0 5 5 5 0 RNA helicase AAA_19 PF13245.6 EER25002.1 - 0.0038 17.6 3.7 0.28 11.5 0.0 4.5 5 0 0 5 5 3 1 AAA domain AAA_24 PF13479.6 EER25002.1 - 0.0039 16.9 1.0 12 5.6 0.0 4.3 4 0 0 4 4 4 0 AAA domain IstB_IS21 PF01695.17 EER25002.1 - 0.0071 16.1 0.8 0.67 9.7 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein Rad17 PF03215.15 EER25002.1 - 0.012 15.6 0.1 6.5 6.6 0.0 4.0 4 0 0 4 4 4 0 Rad17 P-loop domain PduV-EutP PF10662.9 EER25002.1 - 0.027 14.2 1.7 11 5.7 0.1 4.5 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation DUF4482 PF14818.6 EER25002.1 - 0.04 14.8 10.0 28 5.6 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) Vps23_core PF09454.10 EER25002.1 - 0.16 11.9 1.7 8.7 6.4 0.7 3.2 2 0 0 2 2 2 0 Vps23 core domain DUF3450 PF11932.8 EER25002.1 - 0.84 8.9 21.6 0.047 13.0 1.6 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Acetyltransf_1 PF00583.25 EER25003.1 - 1.1e-06 28.9 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.8 EER25003.1 - 0.00084 18.9 0.6 0.0013 18.3 0.6 1.2 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_7 PF13508.7 EER25003.1 - 0.0012 19.3 0.0 0.0028 18.0 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Fig1 PF12351.8 EER25003.1 - 0.024 14.6 0.3 0.038 13.9 0.3 1.2 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Acetyltransf_10 PF13673.7 EER25003.1 - 0.052 13.5 0.0 0.58 10.1 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Svf1_C PF17187.4 EER25005.1 - 5.8e-64 214.9 0.1 2.8e-63 212.7 0.0 2.0 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EER25005.1 - 8e-53 178.8 0.1 1.1e-52 178.3 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Ribosomal_L11 PF00298.19 EER25006.1 - 7.6e-27 93.6 0.1 1.5e-26 92.6 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EER25006.1 - 1.6e-26 91.9 0.2 2.4e-26 91.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 EER25007.1 - 5e-40 137.5 0.0 7.6e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25007.1 - 5.4e-21 75.0 0.0 8.6e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER25007.1 - 0.00059 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EER25007.1 - 0.0025 17.8 0.2 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EER25007.1 - 0.029 13.3 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EER25007.1 - 0.096 12.3 0.1 12 5.5 0.1 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3337 PF11816.8 EER25008.1 - 3.9e-51 173.3 0.0 8.1e-51 172.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EER25008.1 - 1.7e-18 66.6 19.9 0.0031 18.3 0.1 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25008.1 - 0.00012 22.3 1.7 1.6 9.1 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER25008.1 - 0.0014 17.4 1.5 0.0014 17.4 1.5 2.5 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EER25008.1 - 0.0014 17.4 0.2 1 8.0 0.0 3.9 3 1 1 4 4 4 1 Nup133 N terminal like APP_N PF02177.16 EER25008.1 - 0.035 14.5 0.0 0.14 12.5 0.0 2.1 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding MFS_1 PF07690.16 EER25009.1 - 1.1e-37 129.8 28.9 1.1e-37 129.8 28.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EER25009.1 - 0.012 14.5 7.1 0.17 10.7 6.4 2.4 2 0 0 2 2 2 0 MFS_1 like family Phage_holin_2_4 PF16082.5 EER25009.1 - 0.036 13.8 1.5 1.7 8.5 0.1 3.5 3 0 0 3 3 3 0 Bacteriophage holin family, superfamily II-like Mito_carr PF00153.27 EER25010.1 - 1.2e-45 153.3 1.5 7.2e-21 73.9 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein ATP_bind_3 PF01171.20 EER25011.1 - 1.3e-39 135.9 0.0 1.5e-38 132.4 0.0 2.3 2 1 0 2 2 2 1 PP-loop family NAD_synthase PF02540.17 EER25011.1 - 0.087 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase RhoGEF PF00621.20 EER25012.1 - 5.5e-21 75.6 0.0 1.3e-20 74.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 EER25012.1 - 0.00021 21.0 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) HALZ PF02183.18 EER25012.1 - 2.2 8.6 5.0 1 9.7 1.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper CENP-H PF05837.12 EER25012.1 - 2.3 8.7 11.2 6.1 7.3 0.7 3.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.22 EER25012.1 - 5.2 7.4 8.4 20 5.5 2.4 3.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sec7 PF01369.20 EER25014.1 - 1.6e-64 216.9 0.0 2.6e-64 216.3 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EER25014.1 - 2.5e-22 79.5 0.1 1.8e-20 73.5 0.0 3.2 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_14 PF13428.6 EER25015.1 - 3.9e-13 49.0 15.0 4.4 8.4 0.0 12.2 9 4 4 13 13 13 3 Tetratricopeptide repeat Suf PF05843.14 EER25015.1 - 7.2e-11 42.6 18.8 0.029 14.4 0.2 6.9 5 2 1 6 6 6 5 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EER25015.1 - 2e-08 33.8 2.1 0.47 10.8 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EER25015.1 - 3.3e-08 33.5 13.4 0.037 14.0 0.1 7.3 6 1 0 6 6 6 3 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 EER25015.1 - 4.6e-06 26.8 9.9 9 6.7 0.0 7.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 EER25015.1 - 6.7e-06 25.8 11.4 1.6 9.1 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EER25015.1 - 0.0032 17.7 6.5 13 6.4 0.0 7.2 9 0 0 9 9 8 1 Tetratricopeptide repeat NRDE-2 PF08424.10 EER25015.1 - 0.0055 15.9 8.8 0.17 11.0 2.1 5.8 2 2 1 3 3 3 1 NRDE-2, necessary for RNA interference MIT PF04212.18 EER25015.1 - 0.0072 16.4 0.0 0.18 11.9 0.1 3.4 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain HAT PF02184.16 EER25015.1 - 0.08 12.9 7.7 2.9 7.9 0.0 5.8 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.6 EER25015.1 - 0.17 12.6 2.6 91 4.0 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 EER25015.1 - 6.3 7.7 0.0 6.3 7.7 0.0 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 EER25016.1 - 8.2e-71 237.9 1.1 1e-70 237.6 1.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 EER25016.1 - 0.0066 16.5 0.6 0.066 13.3 0.1 2.4 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 RICH PF05062.12 EER25016.1 - 0.054 13.8 1.7 0.11 12.8 0.4 2.0 2 0 0 2 2 2 0 RICH domain HtrL_YibB PF09612.10 EER25016.1 - 0.057 12.9 0.3 0.086 12.4 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) APG6_N PF17675.1 EER25016.1 - 0.075 13.6 0.9 0.17 12.4 0.3 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3919 PF13057.6 EER25016.1 - 0.078 12.6 0.4 0.11 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3919) CobA_CobO_BtuR PF02572.15 EER25016.1 - 0.092 13.0 0.4 0.54 10.5 0.1 2.1 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP BLOC1_2 PF10046.9 EER25016.1 - 0.16 12.3 1.3 13 6.2 0.0 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RRM_1 PF00076.22 EER25017.1 - 1.1e-24 86.0 1.5 5.1e-12 45.4 0.6 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER25017.1 - 2.8e-05 23.7 0.0 0.00059 19.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER25017.1 - 4.7e-05 23.2 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 EER25017.1 - 0.0053 16.6 0.1 0.025 14.4 0.0 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 EER25017.1 - 1 9.5 6.0 21 5.3 0.2 3.7 3 2 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter TFCD_C PF12612.8 EER25018.1 - 2.8e-35 121.9 0.0 1.1e-34 120.0 0.0 2.0 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 EER25018.1 - 7.3e-05 23.1 3.4 0.99 9.8 0.2 5.2 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EER25018.1 - 0.0016 18.5 16.8 1.3 9.5 0.1 7.4 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.7 EER25018.1 - 0.0098 15.9 2.1 1.5 8.8 0.1 4.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EER25018.1 - 0.019 14.1 2.0 0.21 10.7 0.6 2.8 2 1 0 2 2 2 0 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 EER25018.1 - 0.029 15.0 0.5 21 5.8 0.0 4.2 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.16 EER25018.1 - 0.062 14.0 2.0 5.3 8.0 0.1 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Arm PF00514.23 EER25018.1 - 0.078 13.1 0.9 5.2 7.3 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EER25018.1 - 4.9 7.8 16.3 7.1 7.2 0.2 6.6 8 1 1 9 9 9 0 HEAT-like repeat Pkinase PF00069.25 EER25020.1 - 2.2e-59 201.0 0.0 4.5e-59 200.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25020.1 - 2.7e-35 121.9 0.0 4.8e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EER25020.1 - 3.9e-29 100.6 16.4 6.5e-16 58.2 4.2 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EER25020.1 - 7.4e-21 73.8 29.3 1.3e-12 47.4 9.7 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EER25020.1 - 4.4e-14 52.9 1.6 1.2e-13 51.5 1.6 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EER25020.1 - 2.1e-07 31.1 0.0 4.2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EER25020.1 - 0.01 15.2 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.6 EER25020.1 - 3 8.0 5.9 1 9.5 0.9 2.4 2 0 0 2 2 2 0 Up-regulated During Septation zf-RING_9 PF13901.6 EER25020.1 - 4.1 7.3 22.5 3.2 7.7 7.7 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon MFS_1 PF07690.16 EER25021.1 - 4.4e-26 91.7 45.2 1.3e-19 70.3 15.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily eIF-1a PF01176.19 EER25023.1 - 9.3e-19 67.0 0.0 1.2e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.13 EER25024.1 - 8.5e-139 462.9 17.2 9.7e-139 462.7 17.2 1.0 1 0 0 1 1 1 1 ALG3 protein COA2 PF17051.5 EER25025.1 - 0.0088 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 RP-C PF03428.13 EER25025.1 - 0.064 12.9 0.7 0.1 12.3 0.7 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Metallophos PF00149.28 EER25026.1 - 1.2e-31 110.8 0.0 4e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Fungal_trans PF04082.18 EER25027.1 - 2.1e-42 145.0 0.0 4.5e-42 143.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER25027.1 - 7.5e-08 32.4 9.0 1.6e-07 31.4 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 EER25027.1 - 0.031 14.2 6.5 0.026 14.4 4.5 1.9 2 0 0 2 2 2 0 PHD-finger MnmE_helical PF12631.7 EER25027.1 - 0.1 12.8 0.3 0.18 12.0 0.3 1.3 1 0 0 1 1 1 0 MnmE helical domain bZIP_1 PF00170.21 EER25028.1 - 0.013 15.6 8.7 0.013 15.6 8.7 2.7 3 0 0 3 3 3 0 bZIP transcription factor bZIP_2 PF07716.15 EER25028.1 - 0.017 15.2 11.7 0.017 15.2 11.7 2.2 3 0 0 3 3 3 0 Basic region leucine zipper UCH PF00443.29 EER25029.1 - 3.8e-33 115.1 0.2 6.5e-33 114.3 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER25029.1 - 1.1e-07 31.7 5.6 7.9e-07 29.0 5.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AsnC_trans_reg PF01037.21 EER25029.1 - 0.092 12.7 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain DNA_ligase_A_M PF01068.21 EER25030.1 - 3.5e-45 154.2 0.0 7.9e-45 153.0 0.0 1.6 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EER25030.1 - 1e-42 146.4 0.0 2e-42 145.4 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 EER25030.1 - 3.3e-19 69.1 0.0 7.6e-15 55.1 0.1 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EER25030.1 - 5.2e-16 59.4 0.0 9.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 EER25030.1 - 3.4e-14 53.3 0.0 1e-13 51.7 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 EER25030.1 - 9.8e-10 38.7 0.0 1.1e-06 28.8 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EER25030.1 - 2.5e-07 30.9 0.5 0.0011 19.2 0.0 2.4 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EER25030.1 - 0.013 15.4 0.0 0.2 11.5 0.1 2.3 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EER25030.1 - 0.018 15.0 0.0 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 twin BRCT domain DNA_ligase_IV PF11411.8 EER25030.1 - 0.074 13.2 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 DNA ligase IV EF-hand_4 PF12763.7 EER25031.1 - 2.8e-06 27.2 0.0 5.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Fungal_trans PF04082.18 EER25032.1 - 0.00021 20.4 0.0 0.00041 19.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER25032.1 - 0.00022 21.3 8.6 0.00098 19.2 8.5 2.1 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spb1_C PF07780.12 EER25034.1 - 4.2e-83 278.1 29.3 4.2e-83 278.1 29.3 3.0 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EER25034.1 - 5.9e-56 189.4 0.1 1.2e-55 188.4 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EER25034.1 - 1.8e-53 180.7 10.5 1.8e-53 180.7 10.5 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 EER25034.1 - 0.026 14.4 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EER25034.1 - 0.14 11.8 1.6 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F EamA PF00892.20 EER25035.1 - 1.5e-12 47.8 35.9 3.1e-07 30.6 2.0 3.1 3 0 0 3 3 3 3 EamA-like transporter family DUF3955 PF13127.6 EER25035.1 - 6.2e-07 29.1 1.7 6.2e-07 29.1 1.7 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 EER25035.1 - 1.4e-06 27.8 0.3 1.4e-06 27.8 0.3 2.0 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 EER25035.1 - 3.2e-06 26.9 16.1 4.7e-06 26.3 11.8 2.0 2 0 0 2 2 2 1 Solute carrier family 35 Ras PF00071.22 EER25036.1 - 2.2e-55 186.6 0.1 2.6e-55 186.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER25036.1 - 3e-31 108.1 0.0 4.5e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER25036.1 - 1.3e-11 44.3 0.0 1.5e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EER25036.1 - 1.3e-07 31.7 0.0 1.9e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EER25036.1 - 4e-07 29.6 0.0 4.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EER25036.1 - 2.1e-05 24.2 0.0 0.00086 18.9 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EER25036.1 - 0.00017 21.6 0.2 0.0032 17.4 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 EER25036.1 - 0.0046 16.4 0.0 0.0061 16.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EER25036.1 - 0.0055 17.0 0.0 0.0098 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EER25036.1 - 0.0062 16.3 0.2 0.19 11.5 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EER25036.1 - 0.0076 16.3 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 EER25036.1 - 0.014 15.2 0.4 0.36 10.6 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EER25036.1 - 0.014 15.7 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 EER25036.1 - 0.018 14.7 0.0 0.035 13.7 0.0 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EER25036.1 - 0.019 14.2 0.0 0.056 12.7 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_7 PF12775.7 EER25036.1 - 0.021 14.4 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EER25036.1 - 0.021 14.5 0.1 0.049 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EER25036.1 - 0.048 12.8 0.1 0.31 10.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EER25036.1 - 0.077 12.9 1.3 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 EER25036.1 - 0.081 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein RNA_helicase PF00910.22 EER25036.1 - 0.092 13.1 0.0 0.72 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EER25036.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EER25036.1 - 0.16 12.5 0.2 0.23 12.0 0.3 1.7 1 1 0 1 1 1 0 ABC transporter ATG16 PF08614.11 EER25037.1 - 2.4e-59 200.9 10.4 2.7e-59 200.8 10.4 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 EER25037.1 - 0.023 14.2 10.8 0.031 13.8 10.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CCDC144C PF14915.6 EER25037.1 - 0.064 12.4 19.0 0.022 13.9 14.9 2.0 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region IF2_N PF04760.15 EER25037.1 - 0.066 13.0 0.2 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FAM76 PF16046.5 EER25037.1 - 0.2 11.0 3.4 0.24 10.7 3.4 1.2 1 0 0 1 1 1 0 FAM76 protein Sec20 PF03908.13 EER25037.1 - 0.23 11.4 3.3 1.9 8.4 0.8 2.3 1 1 1 2 2 2 0 Sec20 ADK PF00406.22 EER25037.1 - 0.72 10.0 4.8 13 5.9 1.5 2.6 2 1 1 3 3 3 0 Adenylate kinase UPF0242 PF06785.11 EER25037.1 - 0.75 9.9 13.6 0.49 10.5 5.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 EER25037.1 - 1.9 9.0 13.5 0.19 12.3 7.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 EER25037.1 - 2.5 7.8 19.2 0.53 10.1 8.8 2.6 2 1 1 3 3 3 0 Ezrin/radixin/moesin family DOT1 PF08123.13 EER25038.1 - 2.7e-77 258.9 0.0 3.9e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PH PF00169.29 EER25039.1 - 6.3e-12 45.9 0.3 9.2e-12 45.4 0.3 1.3 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EER25039.1 - 0.0026 18.1 0.2 0.038 14.4 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EER25039.1 - 0.014 15.8 3.9 0.022 15.2 3.9 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain Glyco_transf_15 PF01793.16 EER25040.1 - 7.9e-95 317.8 11.0 7.4e-94 314.6 11.0 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ran_BP1 PF00638.18 EER25042.1 - 2e-50 170.1 1.8 3.1e-50 169.5 1.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EER25042.1 - 4.6e-06 26.6 0.6 2.8e-05 24.0 0.6 1.9 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 EER25042.1 - 5.2e-05 23.5 0.1 7.3e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 VID27 PH-like domain CDC27 PF09507.10 EER25042.1 - 0.059 12.7 19.0 0.082 12.3 19.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YEATS PF03366.16 EER25043.1 - 2e-18 66.1 0.1 3.7e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EER25043.1 - 1e-05 25.6 0.4 2.1e-05 24.6 0.2 1.7 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Methyltr_RsmB-F PF01189.17 EER25045.1 - 2.2e-16 60.1 0.0 3.3e-09 36.7 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PB1 PF00564.24 EER25045.1 - 0.11 12.4 0.0 6.9 6.7 0.0 2.6 2 0 0 2 2 2 0 PB1 domain Phosducin PF02114.16 EER25046.1 - 1.2e-13 50.7 1.3 1e-12 47.6 0.0 2.5 2 1 0 2 2 2 1 Phosducin CAP59_mtransfer PF11735.8 EER25047.1 - 3.8e-71 239.6 0.0 4.8e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 2-Hacid_dh_C PF02826.19 EER25048.1 - 2.4e-53 180.2 0.0 3.1e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER25048.1 - 2.7e-15 56.2 0.0 3.3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EER25048.1 - 5.5e-05 23.4 0.0 9.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EER25048.1 - 0.0046 17.5 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EER25048.1 - 0.1 13.0 0.0 12 6.4 0.0 2.3 1 1 1 2 2 2 0 Putative NAD(P)-binding WD40 PF00400.32 EER25049.1 - 1.1e-36 124.2 20.1 7.2e-06 26.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25049.1 - 3.8e-15 56.0 0.0 0.00047 20.4 0.0 4.9 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER25049.1 - 3.8e-05 23.6 0.0 0.14 12.0 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EER25049.1 - 0.00018 21.0 0.2 0.0039 16.5 0.0 2.6 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EER25049.1 - 0.014 14.4 0.3 14 4.5 0.0 3.8 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-MYND PF01753.18 EER25050.1 - 1.2e-07 31.7 20.5 1.2e-07 31.7 20.5 1.9 2 0 0 2 2 2 1 MYND finger ORC6 PF05460.13 EER25050.1 - 3.3 6.9 5.8 1.3 8.2 0.8 2.3 3 0 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) DIOX_N PF14226.6 EER25051.1 - 1.3e-19 71.1 0.1 1.9e-19 70.5 0.1 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EER25051.1 - 7.4e-16 58.5 0.0 2.1e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 EER25052.1 - 3.7e-78 262.1 0.0 6.1e-78 261.4 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EER25052.1 - 5.8e-32 109.9 0.0 1.6e-31 108.5 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 EER25052.1 - 0.00027 21.2 0.0 0.00072 19.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EER25052.1 - 0.03 14.8 0.0 0.081 13.4 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain Thioredoxin PF00085.20 EER25053.1 - 2.3e-55 184.9 0.0 1e-26 92.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EER25053.1 - 7.1e-25 87.7 1.1 3.9e-24 85.4 0.5 2.3 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EER25053.1 - 1.5e-13 51.1 0.0 3.3e-05 24.3 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EER25053.1 - 9.2e-11 41.6 0.0 0.00023 20.6 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EER25053.1 - 3.3e-09 36.7 0.0 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 EER25053.1 - 4.6e-07 29.9 0.0 0.0015 18.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EER25053.1 - 1.1e-06 28.9 0.0 0.049 14.0 0.0 3.3 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_4 PF13462.6 EER25053.1 - 0.0012 19.0 0.7 1.1 9.4 0.0 3.9 3 2 2 5 5 5 1 Thioredoxin Redoxin PF08534.10 EER25053.1 - 0.0026 17.5 0.1 0.62 9.8 0.1 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.6 EER25053.1 - 0.0038 17.0 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 EER25053.1 - 0.19 12.0 0.2 21 5.4 0.3 2.7 2 1 0 2 2 2 0 Glutaredoxin Ebp2 PF05890.12 EER25054.1 - 8.1e-98 327.2 14.8 8.1e-98 327.2 14.8 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 DNMT1-RFD PF12047.8 EER25055.1 - 0.038 14.0 0.0 0.097 12.7 0.0 1.7 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain TruB_N PF01509.18 EER25056.1 - 5.4e-45 153.4 0.0 1.7e-44 151.8 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EER25056.1 - 3.2e-07 30.4 0.0 6.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain FHA PF00498.26 EER25058.1 - 4.1e-14 52.7 0.0 1.1e-13 51.3 0.0 1.7 2 0 0 2 2 1 1 FHA domain zf-RING_11 PF17123.5 EER25058.1 - 1.3e-10 40.8 4.8 2.9e-10 39.7 4.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EER25058.1 - 4.1e-07 30.2 9.6 9.4e-07 29.1 9.6 1.7 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EER25058.1 - 1.9e-05 24.9 0.0 3.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 EER25058.1 - 0.00094 19.1 7.6 0.0017 18.3 7.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING-like PF08746.11 EER25058.1 - 0.0082 16.4 6.3 0.018 15.3 6.3 1.6 1 0 0 1 1 1 1 RING-like domain zf-C3HC4 PF00097.25 EER25058.1 - 0.021 14.7 9.4 0.044 13.7 9.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EER25058.1 - 0.021 14.8 3.8 0.054 13.5 3.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EER25058.1 - 0.028 14.3 9.5 0.063 13.1 9.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EER25058.1 - 0.12 12.7 9.6 0.52 10.6 9.6 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 EER25058.1 - 0.49 10.3 6.3 0.95 9.4 6.3 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 EER25058.1 - 2.7 7.7 8.6 5.7 6.6 8.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 EER25058.1 - 7.5 6.8 8.9 10 6.3 7.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Bestrophin PF01062.21 EER25059.1 - 1.2e-57 195.6 0.0 1.5e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel AAA_lid_2 PF17863.1 EER25060.1 - 0.047 13.5 0.3 0.098 12.5 0.3 1.5 1 0 0 1 1 1 0 AAA lid domain Vps16_N PF04841.13 EER25061.1 - 1.3e-99 333.7 0.0 1.8e-99 333.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EER25061.1 - 3.6e-89 299.0 0.0 5.1e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EER25061.1 - 9.7e-05 22.6 0.0 0.01 16.1 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Alb1 PF09135.11 EER25062.1 - 6.2e-34 117.0 10.2 1.1e-33 116.2 10.2 1.4 1 0 0 1 1 1 1 Alb1 Mu-like_Pro PF10123.9 EER25062.1 - 0.028 14.0 3.7 0.032 13.8 3.7 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein MAT1 PF06391.13 EER25062.1 - 0.1 12.4 4.9 0.14 11.9 4.9 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Pkinase PF00069.25 EER25063.1 - 8.8e-74 248.2 0.0 1e-73 248.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25063.1 - 2.9e-34 118.5 0.0 3.6e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EER25063.1 - 1.1e-06 27.8 0.0 1.3e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EER25063.1 - 0.0068 15.8 0.1 0.012 15.0 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER25063.1 - 0.0071 16.3 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EER25063.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EER25063.1 - 0.018 14.4 0.0 0.051 12.9 0.0 1.7 1 1 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 EER25063.1 - 0.027 13.5 0.1 0.19 10.7 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 RhoGAP PF00620.27 EER25064.1 - 0.011 15.5 0.0 0.03 14.2 0.0 1.8 1 1 0 1 1 1 0 RhoGAP domain CBS PF00571.28 EER25065.1 - 1.3e-22 80.0 5.4 5.8e-09 36.3 0.1 4.3 4 0 0 4 4 4 4 CBS domain CRAL_TRIO PF00650.20 EER25066.1 - 1.3e-37 128.9 0.0 1.8e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EER25066.1 - 8e-17 61.2 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EER25066.1 - 0.01 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.10 EER25067.1 - 3.3e-82 276.2 0.2 5.1e-82 275.6 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EER25067.1 - 6.9e-40 136.7 0.0 9.5e-40 136.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B LTV PF04180.14 EER25067.1 - 0.19 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Low temperature viability protein IF-2B PF01008.17 EER25068.1 - 7.9e-78 261.5 0.3 1.1e-77 261.1 0.3 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family PP_kinase_C_1 PF17941.1 EER25068.1 - 0.11 12.1 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 Macoilin PF09726.9 EER25068.1 - 5 5.6 7.5 7 5.1 7.5 1.2 1 0 0 1 1 1 0 Macoilin family Kinesin PF00225.23 EER25069.1 - 1.1e-113 379.5 0.0 2e-113 378.7 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EER25069.1 - 2.1e-25 89.4 0.5 5e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 EER25069.1 - 0.012 14.6 9.5 0.022 13.6 9.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein FAM184 PF15665.5 EER25069.1 - 0.044 13.5 13.8 0.097 12.4 13.7 1.6 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B FUSC PF04632.12 EER25069.1 - 0.21 10.1 5.4 0.37 9.3 5.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF87 PF01935.17 EER25069.1 - 0.81 9.7 6.6 0.83 9.7 0.0 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain YabA PF06156.13 EER25069.1 - 0.87 10.3 14.2 15 6.3 7.4 3.5 2 1 1 3 3 3 0 Initiation control protein YabA FAM76 PF16046.5 EER25069.1 - 2 7.7 6.6 5.1 6.4 6.6 1.7 1 0 0 1 1 1 0 FAM76 protein V_ATPase_I PF01496.19 EER25069.1 - 4.1 5.2 9.2 6.5 4.5 9.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5094 PF17015.5 EER25069.1 - 5.9 7.0 9.4 1.3 9.1 5.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) PUL PF08324.11 EER25070.1 - 4.2e-61 206.6 0.1 5.7e-61 206.2 0.1 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EER25070.1 - 1.9e-36 125.2 0.0 3.2e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EER25070.1 - 2.3e-15 56.4 0.0 4.6e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EER25070.1 - 2.9e-05 24.0 0.0 6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 EER25070.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EER25070.1 - 0.0021 18.5 1.9 0.0088 16.5 0.5 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EER25070.1 - 0.0031 17.4 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_3 PF13192.6 EER25070.1 - 0.0037 17.3 0.0 0.009 16.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain DUF2847 PF11009.8 EER25070.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) T4_deiodinase PF00837.17 EER25070.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase Redoxin PF08534.10 EER25070.1 - 0.16 11.6 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Redoxin L_lactis_RepB_C PF06430.12 EER25070.1 - 0.19 11.7 0.1 8.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Lactococcus lactis RepB C-terminus R2K_2 PF18299.1 EER25071.1 - 0.006 16.5 0.0 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain, R2K clade family 2 EF-hand_9 PF14658.6 EER25071.1 - 0.007 16.7 0.0 1.1 9.6 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 EER25071.1 - 0.017 15.0 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain pair R2K_3 PF14243.6 EER25071.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Skp1 PF01466.19 EER25071.1 - 4 7.6 6.3 0.82 9.8 1.7 2.2 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Peptidase_S24 PF00717.23 EER25072.1 - 8.8e-09 35.2 0.1 1.7e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EER25072.1 - 0.00011 22.0 0.0 0.0076 16.0 0.0 2.5 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Sipho_Gp37 PF14594.6 EER25072.1 - 0.075 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein PBP PF01161.20 EER25073.1 - 1.2e-10 41.9 0.0 2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.22 EER25074.1 - 3.4e-49 167.1 0.0 4.6e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_2 PF16113.5 EER25075.1 - 1.4e-131 439.0 0.0 1.8e-131 438.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EER25075.1 - 8.9e-26 90.7 0.0 4e-25 88.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase DUF1264 PF06884.11 EER25076.1 - 4.1e-77 257.6 0.1 4.7e-77 257.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) HAGH_C PF16123.5 EER25077.1 - 1.9e-19 69.9 0.1 3.2e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EER25077.1 - 6.6e-19 68.7 2.2 4.9e-18 65.8 2.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EER25077.1 - 0.00018 21.1 2.4 0.0054 16.3 2.4 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 EER25077.1 - 0.0055 16.2 0.1 0.04 13.4 0.0 2.0 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Las1 PF04031.13 EER25078.1 - 1.2e-46 158.6 0.0 2.3e-46 157.7 0.0 1.5 1 0 0 1 1 1 1 Las1-like Ubiq-assoc PF09145.10 EER25078.1 - 0.028 14.4 0.1 0.056 13.4 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-associated NAD_kinase PF01513.21 EER25080.1 - 6.7e-73 245.4 0.0 1e-72 244.8 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.16 EER25081.1 - 4.5e-38 130.3 0.0 6.8e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component MFAP1 PF06991.11 EER25082.1 - 1.9e-67 227.3 21.0 1.9e-67 227.3 21.0 3.0 2 1 1 3 3 3 1 Microfibril-associated/Pre-mRNA processing Glyco_hydro_16 PF00722.21 EER25083.1 - 6.8e-45 152.7 3.2 1.1e-44 152.0 3.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Rep_fac-A_3 PF08661.11 EER25084.1 - 7.8e-26 90.5 0.0 9.1e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 EER25084.1 - 0.0076 16.2 0.1 0.23 11.4 0.1 2.1 1 1 0 1 1 1 1 Telomere capping, CST complex subunit GATA PF00320.27 EER25085.1 - 0.00032 20.2 4.7 0.021 14.4 1.0 2.6 2 0 0 2 2 2 2 GATA zinc finger zf-RING_7 PF02591.15 EER25085.1 - 0.21 11.8 0.5 0.48 10.6 0.5 1.7 1 0 0 1 1 1 0 C4-type zinc ribbon domain LSM PF01423.22 EER25086.1 - 1.4e-07 31.1 0.0 1.5e-07 31.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.17 EER25087.1 - 1.2e-105 352.9 0.5 1.5e-105 352.5 0.5 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EER25087.1 - 1.8e-45 154.9 0.0 3.3e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 DAK2 domain Cullin PF00888.22 EER25088.1 - 5.5e-179 596.7 5.6 6.8e-179 596.4 5.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EER25088.1 - 2e-23 82.2 1.1 5.4e-23 80.8 1.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.11 EER25088.1 - 0.067 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 HbrB-like Nup192 PF11894.8 EER25089.1 - 0 1330.3 12.1 0 1330.1 12.1 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 RPAP3_C PF13877.6 EER25089.1 - 0.42 11.2 2.6 17 6.0 0.0 3.9 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 PI3_PI4_kinase PF00454.27 EER25090.1 - 2.8e-53 181.3 0.0 5.9e-53 180.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EER25090.1 - 1.7e-36 125.6 0.1 2.3e-35 122.0 0.0 3.2 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EER25090.1 - 1.3e-11 44.1 1.6 4.3e-11 42.4 0.2 2.7 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 EER25090.1 - 7.2e-09 35.3 5.2 1.7e-08 34.1 5.2 1.6 1 0 0 1 1 1 1 FAT domain Hypoth_Ymh PF09509.10 EER25090.1 - 1.9 8.4 4.2 20 5.1 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (Hypoth_ymh) UPF0052 PF01933.18 EER25095.1 - 4.8e-60 203.3 0.0 6e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4 PF00097.25 EER25096.1 - 3.1e-09 36.6 3.9 6.8e-09 35.5 4.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER25096.1 - 3.6e-09 36.3 7.1 1.2e-08 34.7 3.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER25096.1 - 1.2e-08 34.7 7.9 3.2e-08 33.3 7.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER25096.1 - 5.4e-08 32.7 6.5 5.6e-07 29.5 3.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EER25096.1 - 2.3e-07 30.6 6.9 3.9e-07 29.9 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EER25096.1 - 2.9e-07 30.7 7.3 5.2e-07 29.9 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EER25096.1 - 4.1e-05 23.3 7.4 0.00053 19.8 7.4 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EER25096.1 - 0.00015 21.8 2.6 0.00015 21.8 2.6 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-4CXXC_R1 PF10497.9 EER25096.1 - 0.023 14.9 3.2 0.31 11.3 3.4 2.0 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Rad50_zn_hook PF04423.14 EER25096.1 - 0.029 14.2 1.6 0.51 10.2 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-rbx1 PF12678.7 EER25096.1 - 0.03 14.6 5.6 0.071 13.4 5.6 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EER25096.1 - 0.36 10.9 4.0 1 9.4 4.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1644 PF07800.12 EER25096.1 - 0.44 10.6 6.6 0.53 10.3 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_6 PF14835.6 EER25096.1 - 0.46 10.4 4.2 0.25 11.2 1.3 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Zn_Tnp_IS91 PF14319.6 EER25096.1 - 0.97 9.5 5.2 0.8 9.8 2.7 1.9 1 1 1 2 2 2 0 Transposase zinc-binding domain Gin PF10764.9 EER25096.1 - 2 8.4 7.1 1.3 9.1 4.9 1.7 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin zf-RING_4 PF14570.6 EER25096.1 - 2.3 8.1 7.9 12 5.8 8.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DNApol_Exo PF18136.1 EER25097.1 - 1.6e-105 352.3 0.0 2.6e-105 351.6 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EER25097.1 - 5.5e-57 193.5 0.0 9.3e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A Mad3_BUB1_I PF08311.12 EER25097.1 - 0.12 12.4 0.4 0.28 11.2 0.4 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 1 CorA PF01544.18 EER25098.1 - 1.4e-24 87.0 5.4 3.2e-19 69.4 1.6 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein PrgI PF12666.7 EER25098.1 - 0.051 14.3 1.6 0.09 13.5 1.6 1.3 1 0 0 1 1 1 0 PrgI family protein EMP70 PF02990.16 EER25098.1 - 0.5 9.0 3.2 0.7 8.5 3.2 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 SQS_PSY PF00494.19 EER25099.1 - 2.8e-52 177.8 0.0 3.7e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase LSM PF01423.22 EER25100.1 - 9.6e-19 66.9 0.3 1.3e-18 66.4 0.3 1.2 1 0 0 1 1 1 1 LSM domain GTP_EFTU PF00009.27 EER25101.1 - 2.9e-19 69.4 0.0 4.7e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EER25101.1 - 1.9e-09 37.8 1.6 8e-09 35.8 1.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EER25101.1 - 1.8e-05 25.0 0.0 4.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EER25101.1 - 0.0034 17.4 0.0 0.011 15.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EER25101.1 - 0.011 15.5 0.3 2.2 8.0 0.1 3.1 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EER25101.1 - 0.013 15.4 0.1 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 EER25101.1 - 0.032 14.3 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Roc PF08477.13 EER25101.1 - 0.1 12.8 0.1 3.1 8.1 0.0 2.6 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SNF2_N PF00176.23 EER25103.1 - 2.5e-67 227.1 0.0 3.4e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EER25103.1 - 2e-23 82.1 0.0 3.7e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EER25103.1 - 1.5e-14 54.3 0.0 5e-14 52.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EER25103.1 - 0.00017 21.4 5.8 0.00039 20.2 5.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER25103.1 - 0.0002 21.2 5.7 0.00037 20.3 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER25103.1 - 0.00023 21.0 9.5 0.00046 20.0 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PLU-1 PF08429.11 EER25103.1 - 0.00065 19.0 0.7 0.0014 17.9 0.7 1.5 1 0 0 1 1 1 1 PLU-1-like protein zf-RING_UBOX PF13445.6 EER25103.1 - 0.00071 19.6 8.8 0.0016 18.4 8.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EER25103.1 - 0.0013 18.6 7.8 0.0028 17.6 7.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 EER25103.1 - 0.0023 18.0 0.0 0.0074 16.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EER25103.1 - 0.0038 17.5 8.6 0.0097 16.2 8.6 1.8 1 0 0 1 1 1 1 Ring finger domain UBA_4 PF14555.6 EER25103.1 - 0.0068 16.2 0.6 0.9 9.4 0.0 2.6 2 0 0 2 2 2 1 UBA-like domain zf-C3HC4_4 PF15227.6 EER25103.1 - 0.071 13.3 8.1 0.14 12.3 8.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EER25103.1 - 3.5 7.6 8.6 16 5.4 8.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 ATP13 PF12921.7 EER25104.1 - 1.8e-30 105.2 0.0 4.2e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 EER25104.1 - 4.5e-10 39.4 0.0 5.7e-08 32.7 0.0 2.5 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_2 PF13041.6 EER25104.1 - 1.1e-08 35.1 0.0 0.00019 21.6 0.0 2.7 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 EER25104.1 - 0.0067 16.6 0.8 0.14 12.5 0.2 3.1 3 0 0 3 3 3 1 PPR repeat PIG-L PF02585.17 EER25105.1 - 2.8e-28 99.1 0.0 3.9e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF3153 PF11353.8 EER25107.1 - 0.049 13.2 0.4 0.072 12.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Mei4 PF13971.6 EER25108.1 - 0.0004 20.0 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 Asp4 PF16996.5 EER25108.1 - 0.16 11.8 0.3 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 DnaJ PF00226.31 EER25109.1 - 1.5e-19 69.8 0.7 4.4e-19 68.4 0.7 1.9 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 EER25109.1 - 0.14 12.0 0.0 0.55 10.1 0.1 2.0 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Presenilin PF01080.17 EER25109.1 - 2 7.1 3.2 3.1 6.5 3.2 1.4 1 0 0 1 1 1 0 Presenilin DCP2 PF05026.13 EER25110.1 - 3e-30 104.4 1.7 5.6e-30 103.5 1.7 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EER25110.1 - 1.8e-17 63.6 0.1 4.1e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.21 EER25110.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain DUF4112 PF13430.6 EER25111.1 - 3.4e-35 120.5 0.3 4.4e-35 120.1 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HSP70 PF00012.20 EER25112.1 - 0.11 10.7 2.6 1.8 6.6 0.0 2.8 3 0 0 3 3 3 0 Hsp70 protein Glyco_hydro_47 PF01532.20 EER25115.1 - 1.3e-178 594.6 0.0 1.6e-178 594.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_127 PF07944.12 EER25115.1 - 0.0094 14.5 0.0 0.34 9.4 0.0 2.1 2 0 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 CTU2 PF10288.9 EER25116.1 - 3.4e-10 40.2 0.3 3.2e-09 37.0 0.3 2.3 1 1 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 Lung_7-TM_R PF06814.13 EER25117.1 - 8.9e-71 238.5 18.7 1.1e-70 238.3 18.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor MATalpha_HMGbox PF04769.12 EER25118.1 - 0.02 14.2 0.1 0.1 11.9 0.1 1.9 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 HMG-box CHAT PF12770.7 EER25119.1 - 2.3e-20 73.2 0.1 4.5e-20 72.2 0.0 1.5 2 0 0 2 2 2 1 CHAT domain Raptor_N PF14538.6 EER25119.1 - 0.15 12.0 0.0 0.98 9.4 0.0 2.1 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain ABC_tran PF00005.27 EER25120.1 - 3.6e-13 50.2 0.1 3.2e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter TolA_bind_tri PF16331.5 EER25120.1 - 0.018 15.1 0.9 0.043 13.9 0.9 1.7 1 0 0 1 1 1 0 TolA binding protein trimerisation DivIC PF04977.15 EER25120.1 - 0.03 14.1 2.2 0.03 14.1 2.2 2.1 3 0 0 3 3 3 0 Septum formation initiator HEPN_RiboL-PSP PF18735.1 EER25120.1 - 0.098 12.6 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 RiboL-PSP-HEPN TMCO5 PF14992.6 EER25120.1 - 0.15 11.6 1.0 0.26 10.8 0.8 1.4 1 1 0 1 1 1 0 TMCO5 family DUF1308 PF07000.11 EER25121.1 - 9.9e-14 51.6 0.1 5.6e-13 49.2 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 EER25121.1 - 0.00054 19.3 0.2 1.6 8.0 0.2 3.0 3 0 0 3 3 3 2 Family of unknown function (DUF5614) WD40 PF00400.32 EER25122.1 - 3.2e-16 59.4 2.1 3.4e-05 24.5 0.1 6.2 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25122.1 - 3.7e-08 33.5 0.0 0.00065 20.0 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EER25122.1 - 0.0016 17.0 0.0 4 5.9 0.0 3.5 2 1 2 4 4 4 2 Cytochrome D1 heme domain TruB_C PF09142.11 EER25122.1 - 0.077 12.8 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal Mito_carr PF00153.27 EER25123.1 - 1.5e-51 172.3 3.0 2.7e-18 65.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.21 EER25124.1 - 1.8e-122 408.2 0.2 2.2e-122 407.9 0.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Peptidase_S8 PF00082.22 EER25125.1 - 2.9e-11 43.2 0.3 6.5e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Subtilase family SRP9-21 PF05486.12 EER25126.1 - 9.8e-34 115.6 4.5 1.2e-33 115.4 4.5 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) OHCU_decarbox PF09349.10 EER25127.1 - 2.3e-40 138.6 0.0 2.7e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase WD40 PF00400.32 EER25128.1 - 3.3e-25 87.8 5.4 2.8e-05 24.8 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25128.1 - 9.5e-07 29.0 0.1 0.64 10.4 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF4875 PF16175.5 EER25128.1 - 0.0022 18.1 0.4 0.017 15.2 0.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4875) Ge1_WD40 PF16529.5 EER25128.1 - 0.024 13.6 0.2 4 6.3 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EER25128.1 - 0.04 12.6 1.0 0.36 9.4 0.2 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Arm PF00514.23 EER25129.1 - 2.4e-76 249.7 28.1 1e-12 47.6 0.1 11.6 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EER25129.1 - 1.4e-18 67.0 19.5 0.00013 22.4 0.2 8.0 7 2 2 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.6 EER25129.1 - 5.8e-16 58.7 9.3 0.00022 21.5 0.2 6.9 4 2 1 6 6 6 4 HEAT repeats HEAT PF02985.22 EER25129.1 - 1.2e-15 56.3 15.1 0.12 12.7 0.0 9.4 10 0 0 10 10 10 4 HEAT repeat Adaptin_N PF01602.20 EER25129.1 - 9.8e-13 47.5 8.9 1.7e-07 30.2 0.6 2.5 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 EER25129.1 - 1.5e-11 44.2 4.8 1.6e-07 31.0 1.3 2.5 1 1 1 2 2 2 2 Armadillo-like KAP PF05804.12 EER25129.1 - 9.7e-10 37.2 0.1 1.6e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EER25129.1 - 3.2e-08 33.2 2.2 7.1e-05 22.2 0.5 2.6 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EER25129.1 - 0.00012 22.2 7.4 0.11 12.5 0.2 5.0 2 2 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 EER25129.1 - 0.0002 21.3 6.8 1.8 8.6 0.2 4.9 3 2 2 5 5 5 2 Spinocerebellar ataxia type 10 protein domain HEAT_PBS PF03130.16 EER25129.1 - 0.00026 21.4 7.7 1.3 9.9 0.5 6.8 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat DUF5578 PF17741.1 EER25129.1 - 0.00034 20.1 9.6 1 8.7 0.0 4.5 1 1 2 4 4 4 2 Family of unknown function (DUF5578) DUF3361 PF11841.8 EER25129.1 - 0.00056 19.9 9.4 0.28 11.1 0.2 4.1 1 1 2 4 4 4 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EER25129.1 - 0.001 19.2 3.9 7.5 6.7 0.1 4.9 2 1 6 8 8 8 1 V-ATPase subunit H UNC45-central PF11701.8 EER25129.1 - 0.067 13.2 2.0 4.9 7.1 0.2 3.3 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 EER25129.1 - 0.073 13.7 0.1 1.6 9.4 0.0 3.1 2 1 0 3 3 2 0 Vacuolar 14 Fab1-binding region YqfD PF06898.11 EER25129.1 - 0.086 11.7 0.0 0.34 9.7 0.0 1.8 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD EXOSC1 PF10447.9 EER25130.1 - 4.6e-25 88.3 1.2 7e-25 87.8 1.2 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EER25130.1 - 2.2e-11 43.3 0.8 7.4e-11 41.7 0.1 2.2 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region GTP_EFTU PF00009.27 EER25131.1 - 1.3e-56 191.3 0.0 2.1e-56 190.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EER25131.1 - 2.3e-15 56.4 0.0 7.3e-15 54.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EER25131.1 - 9.1e-09 35.6 0.0 2.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EER25131.1 - 1.5e-07 31.4 0.0 3.5e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EER25131.1 - 1.6e-05 24.6 0.0 0.0027 17.5 0.0 2.6 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EER25131.1 - 0.073 13.2 0.0 0.19 11.8 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4604 PF15377.6 EER25132.1 - 5.9e-23 82.2 19.7 6.8e-23 82.0 19.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Prp19 PF08606.11 EER25133.1 - 3.9e-32 110.1 1.8 6.9e-32 109.2 1.8 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EER25133.1 - 3.5e-14 52.9 0.5 7.6e-07 29.3 0.0 4.6 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EER25133.1 - 1.6e-12 47.7 7.1 0.00015 22.5 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 EER25133.1 - 5.9e-07 29.6 0.1 1.5e-05 25.0 0.0 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A V_ATPase_I_N PF18670.1 EER25133.1 - 0.00038 20.8 0.1 0.00081 19.7 0.1 1.5 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain WD40_like PF17005.5 EER25133.1 - 0.0015 17.9 0.4 0.12 11.7 0.3 2.6 1 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EER25133.1 - 0.0065 15.5 0.1 0.012 14.6 0.1 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EER25133.1 - 0.021 13.1 0.0 0.079 11.3 0.1 1.6 1 1 1 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz zf-Nse PF11789.8 EER25133.1 - 0.039 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.16 EER25133.1 - 0.12 10.8 0.9 1.5 7.3 0.4 2.6 1 1 1 2 2 2 0 Cytochrome D1 heme domain zf-RING_5 PF14634.6 EER25134.1 - 0.0017 18.2 1.9 0.0038 17.2 1.9 1.6 1 1 0 1 1 1 1 zinc-RING finger domain BIR PF00653.21 EER25134.1 - 0.022 15.4 0.9 0.048 14.3 0.1 1.9 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain zf-RING_UBOX PF13445.6 EER25134.1 - 0.035 14.1 0.7 0.075 13.1 0.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FYVE PF01363.21 EER25134.1 - 0.23 11.6 2.9 0.47 10.6 2.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 EER25134.1 - 0.23 11.4 2.1 0.81 9.6 2.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EER25134.1 - 0.24 11.4 0.2 0.24 11.4 0.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.6 EER25134.1 - 0.29 11.0 3.2 4.7 7.1 3.7 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 EER25134.1 - 0.34 11.2 4.8 0.75 10.1 1.2 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EER25134.1 - 0.59 10.5 3.7 0.26 11.6 0.9 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.6 EER25134.1 - 0.95 9.4 3.5 4 7.4 3.5 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UBP PF02148.19 EER25134.1 - 3.8 7.9 5.5 0.73 10.2 1.6 1.8 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein L51_S25_CI-B8 PF05047.16 EER25135.1 - 7.2e-16 57.9 1.2 7.7e-16 57.8 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 EER25136.1 - 3.1e-27 95.0 2.4 3.1e-27 95.0 2.4 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EER25136.1 - 5.3e-17 61.4 0.0 1.3e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER25136.1 - 0.00037 20.5 0.0 0.00077 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RL10P_insert PF17777.1 EER25137.1 - 9.3e-23 80.0 0.0 1.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EER25137.1 - 6.3e-19 68.0 0.0 1.3e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 MDM10 PF12519.8 EER25138.1 - 4.3e-151 503.9 6.1 5.3e-131 437.7 7.6 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 TIM PF00121.18 EER25139.1 - 3e-88 295.3 0.0 3.4e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.14 EER25139.1 - 0.029 13.9 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 CutC family DUF3552 PF12072.8 EER25140.1 - 0.48 9.8 9.2 0.98 8.8 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Sugar_tr PF00083.24 EER25141.1 - 5e-87 292.6 24.7 5.8e-87 292.4 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER25141.1 - 2.9e-29 102.1 40.6 6.6e-24 84.5 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro_isomerase PF00160.21 EER25143.1 - 3e-41 141.3 0.0 6.3e-41 140.3 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EER25143.1 - 1.1e-05 25.4 0.0 4.3e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 U-box domain zf-NOSIP PF15906.5 EER25143.1 - 0.0023 18.0 0.0 0.0065 16.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF3602 PF12223.8 EER25143.1 - 0.19 12.3 5.3 0.27 11.9 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) hNIFK_binding PF12196.8 EER25143.1 - 0.78 9.3 4.0 19 4.9 0.2 2.8 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Epimerase PF01370.21 EER25144.1 - 1.1e-14 54.5 0.0 1.5e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EER25144.1 - 2.7e-11 43.0 0.0 2.1e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EER25144.1 - 1.7e-08 34.6 0.0 2.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EER25144.1 - 1.7e-06 27.7 0.0 4.5e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EER25144.1 - 4.4e-06 26.4 0.0 7.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EER25144.1 - 3.1e-05 23.2 0.0 0.00028 20.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EER25144.1 - 3.3e-05 23.2 0.0 0.006 15.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EER25144.1 - 0.0068 15.5 0.1 0.14 11.3 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EER25144.1 - 0.042 13.3 0.0 0.29 10.6 0.0 2.3 3 0 0 3 3 3 0 short chain dehydrogenase KR PF08659.10 EER25144.1 - 0.22 11.4 1.0 13 5.6 0.1 2.3 2 0 0 2 2 2 0 KR domain YjeF_N PF03853.15 EER25145.1 - 7.4e-36 123.6 0.1 1.1e-35 123.0 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EER25145.1 - 1.9e-07 31.9 0.9 1.9e-07 31.9 0.9 2.3 2 0 0 2 2 2 1 FDF domain NTP_transferase PF00483.23 EER25145.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase PIF1 PF05970.14 EER25146.1 - 4.7e-63 213.6 0.1 6.1e-48 163.8 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EER25146.1 - 7.9e-24 84.4 0.0 1.3e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EER25146.1 - 2.6e-12 47.3 0.0 4.3e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EER25146.1 - 2.9e-06 27.6 0.0 7.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EER25146.1 - 8.5e-06 25.4 0.0 1.8e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 EER25146.1 - 0.00011 20.3 0.0 0.00069 17.7 0.0 2.2 3 0 0 3 3 3 1 Helicase UvrD_C_2 PF13538.6 EER25146.1 - 0.00076 19.3 0.1 0.002 17.9 0.1 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EER25146.1 - 0.002 18.5 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain PhoH PF02562.16 EER25146.1 - 0.0047 16.4 0.0 0.013 15.0 0.0 1.7 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.29 EER25146.1 - 0.0062 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EER25146.1 - 0.039 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF5605 PF18310.1 EER25146.1 - 0.05 13.5 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) AAA_11 PF13086.6 EER25146.1 - 0.051 13.3 0.1 0.46 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EER25146.1 - 0.075 13.4 0.1 0.35 11.3 0.0 2.3 2 1 0 2 2 2 0 RNA helicase T2SSE PF00437.20 EER25146.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 EER25146.1 - 0.11 11.7 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain SH3_13 PF18335.1 EER25146.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain ABC_tran PF00005.27 EER25146.1 - 0.14 12.7 0.1 0.64 10.5 0.1 2.0 1 1 0 2 2 2 0 ABC transporter PTCB-BRCT PF12738.7 EER25147.1 - 6.4e-48 160.6 0.4 3.8e-21 74.8 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EER25147.1 - 4.4e-33 113.5 0.0 7.7e-11 42.2 0.0 4.5 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EER25147.1 - 7.1e-17 61.6 0.0 3.7e-05 24.0 0.0 4.4 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EER25147.1 - 1.5e-08 34.8 0.6 1.8 8.9 0.1 4.6 4 1 0 4 4 4 4 DNA ligase 3 BRCT domain MAP65_ASE1 PF03999.12 EER25147.1 - 2.5 6.7 7.4 3.6 6.2 7.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Dynamin_N PF00350.23 EER25148.1 - 3.5e-19 69.5 0.1 1.3e-18 67.7 0.1 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EER25148.1 - 3.3e-10 40.0 0.1 2.9e-09 37.0 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER25148.1 - 5e-07 29.4 0.7 1.2e-05 24.9 0.7 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EER25148.1 - 0.031 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 EER25148.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EER25148.1 - 0.1 13.2 0.1 0.48 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF883 PF05957.13 EER25148.1 - 10 6.8 6.7 48 4.7 0.0 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Snf7 PF03357.21 EER25149.1 - 6.6e-35 120.2 16.3 3.1e-34 118.1 16.1 1.8 2 0 0 2 2 2 1 Snf7 Remorin_C PF03763.13 EER25149.1 - 0.27 11.1 7.1 0.4 10.6 6.3 1.7 1 1 0 1 1 1 0 Remorin, C-terminal region PP2C PF00481.21 EER25150.1 - 1.3e-60 205.2 0.0 8.2e-50 169.8 0.0 3.1 3 0 0 3 3 3 3 Protein phosphatase 2C Mhr1 PF12829.7 EER25151.1 - 8e-29 99.6 0.1 2e-28 98.3 0.1 1.7 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF1974 PF09317.11 EER25151.1 - 0.03 13.9 4.8 0.051 13.1 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Atg14 PF10186.9 EER25152.1 - 3.1e-18 66.0 17.5 1.3e-17 63.9 17.5 1.8 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EER25152.1 - 1.6e-06 27.3 1.7 0.001 18.0 0.1 3.1 3 0 0 3 3 3 2 Vacuolar protein sorting 38 Thioredoxin_5 PF13743.6 EER25152.1 - 0.33 10.6 4.2 0.53 9.9 4.2 1.2 1 0 0 1 1 1 0 Thioredoxin Macoilin PF09726.9 EER25152.1 - 0.79 8.2 7.0 1.1 7.7 7.0 1.1 1 0 0 1 1 1 0 Macoilin family APG6_N PF17675.1 EER25152.1 - 4.7 7.8 15.9 8 7.0 15.9 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Zn_clus PF00172.18 EER25153.1 - 8.8e-07 28.9 14.8 8.8e-07 28.9 14.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.18 EER25154.1 - 6.5e-23 81.1 0.0 1.3e-22 80.1 0.0 1.5 1 1 1 2 2 2 1 O-methyltransferase domain F-box-like PF12937.7 EER25155.1 - 3.2e-06 26.9 0.3 8e-06 25.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like PalH PF08733.10 EER25156.1 - 4.1e-114 381.0 0.2 5.1e-114 380.7 0.2 1.1 1 0 0 1 1 1 1 PalH/RIM21 PLAC8 PF04749.17 EER25157.1 - 5.9e-19 68.9 16.4 8e-19 68.5 16.4 1.2 1 0 0 1 1 1 1 PLAC8 family TIP120 PF08623.10 EER25158.1 - 4.5e-66 221.8 1.0 1.1e-64 217.2 0.1 3.4 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EER25158.1 - 1.5e-13 50.9 12.6 0.0047 17.3 0.1 7.5 5 2 2 7 7 7 4 HEAT repeats HEAT PF02985.22 EER25158.1 - 2.9e-09 36.4 9.6 2 8.9 0.0 10.8 10 0 0 10 10 10 1 HEAT repeat RTP1_C1 PF10363.9 EER25158.1 - 7.4e-05 22.9 5.1 0.0022 18.2 0.1 5.4 5 2 1 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 EER25158.1 - 8.9e-05 23.0 0.0 0.64 10.6 0.0 4.7 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region UME PF08064.13 EER25158.1 - 0.005 16.7 0.0 1 9.3 0.0 4.4 4 0 0 4 4 4 1 UME (NUC010) domain Cnd3 PF12719.7 EER25158.1 - 0.018 14.3 0.5 3.5 6.7 0.1 4.1 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.6 EER25158.1 - 0.029 14.9 18.5 3.1 8.4 0.0 9.3 11 1 1 12 12 12 0 HEAT-like repeat DUF3295 PF11702.8 EER25158.1 - 0.034 13.5 0.1 0.061 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Dopey_N PF04118.14 EER25158.1 - 0.036 13.2 0.1 6.5 5.8 0.0 3.8 4 0 0 4 4 4 0 Dopey, N-terminal IFRD PF05004.13 EER25158.1 - 0.099 11.7 1.4 1.2 8.1 0.0 3.3 3 1 0 3 3 3 0 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 EER25158.1 - 0.38 9.8 14.5 0.96 8.5 0.4 5.2 6 0 0 6 6 6 0 RNAPII transcription regulator C-terminal TRAM_LAG1_CLN8 PF03798.16 EER25160.1 - 3.1e-37 128.3 21.6 5.6e-37 127.4 21.6 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 EER25160.1 - 8.6e-25 86.2 0.0 2.3e-24 84.8 0.0 1.8 1 0 0 1 1 1 1 TRAM1-like protein BSP_II PF05432.11 EER25160.1 - 0.66 9.6 11.6 0.87 9.2 11.6 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Glyco_hydro_127 PF07944.12 EER25161.1 - 6.6e-19 67.8 0.1 6.7e-18 64.5 0.1 2.0 1 1 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Sugar_tr PF00083.24 EER25162.1 - 1e-113 380.6 17.7 1.2e-113 380.3 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER25162.1 - 4.2e-28 98.3 34.4 2.6e-27 95.7 25.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EER25162.1 - 0.0012 17.3 0.5 0.0028 16.2 0.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_5 PF05631.14 EER25162.1 - 0.0016 17.4 0.2 0.0033 16.4 0.2 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Transglut_core PF01841.19 EER25163.1 - 6.5e-12 45.9 0.0 1.2e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 EER25163.1 - 0.082 13.9 0.1 0.36 11.9 0.0 2.0 2 0 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase DUF553 PF04473.12 EER25163.1 - 0.13 11.7 0.0 1.6 8.3 0.0 2.2 1 1 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.22 EER25164.1 - 4.8e-31 107.6 0.1 6.2e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER25164.1 - 1.1e-23 83.7 0.1 1.8e-23 83.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER25164.1 - 1.5e-06 27.8 0.0 2.1e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EER25164.1 - 0.00062 19.2 0.1 0.00081 18.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EER25164.1 - 0.0008 18.4 0.1 0.52 9.1 0.0 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) CAF1C_H4-bd PF12265.8 EER25165.1 - 4.3e-16 58.9 0.1 2e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EER25165.1 - 3.1e-14 53.1 9.7 1.4e-06 28.9 0.1 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25165.1 - 2.8e-08 33.9 2.5 0.0006 20.1 0.4 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER25165.1 - 0.0073 15.0 0.7 0.26 9.9 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 UL41A PF17591.2 EER25165.1 - 0.073 13.2 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL41A Pinin_SDK_N PF04697.13 EER25165.1 - 0.083 13.5 0.5 0.18 12.5 0.5 1.5 1 0 0 1 1 1 0 pinin/SDK conserved region AAA PF00004.29 EER25167.1 - 1.8e-11 44.6 0.1 7.2e-10 39.4 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EER25167.1 - 2.3e-07 30.9 0.3 0.00016 21.7 0.0 2.8 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_16 PF13191.6 EER25167.1 - 1.6e-05 25.3 0.0 7.7e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EER25167.1 - 0.00056 20.5 0.1 0.0065 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EER25167.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EER25167.1 - 0.0058 16.9 0.0 0.018 15.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EER25167.1 - 0.006 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EER25167.1 - 0.04 14.1 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EER25167.1 - 0.044 14.1 0.0 0.091 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EER25167.1 - 0.074 12.8 3.2 0.077 12.8 0.1 2.5 1 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EER25167.1 - 0.098 11.9 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.13 EER25167.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Utp8 PF10395.9 EER25168.1 - 8.8e-15 54.3 0.3 3.9e-13 48.8 0.8 2.8 2 1 0 2 2 2 1 Utp8 family Fungal_trans PF04082.18 EER25169.1 - 1.2e-23 83.5 0.0 2.3e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EER25169.1 - 7.4e-10 38.7 13.0 7.2e-05 23.0 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER25169.1 - 1.2e-06 28.7 12.0 3.2e-06 27.3 6.6 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER25169.1 - 0.00061 20.4 18.0 0.041 14.7 2.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger ADH_zinc_N PF00107.26 EER25170.1 - 5.1e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER25170.1 - 5.4e-05 24.3 0.0 0.00016 22.7 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PX PF00787.24 EER25171.1 - 1.8e-17 63.3 0.1 3.5e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 EER25171.1 - 0.0023 17.1 1.5 0.0054 15.9 1.5 1.6 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Nha1_C PF08619.10 EER25172.1 - 8.4e-105 351.7 26.5 1.3e-104 351.0 26.5 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EER25172.1 - 1.1e-74 251.5 21.0 1.3e-74 251.3 21.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CstA PF02554.14 EER25172.1 - 0.12 11.3 5.0 0.1 11.5 1.4 2.1 2 0 0 2 2 2 0 Carbon starvation protein CstA DUF21 PF01595.20 EER25172.1 - 0.22 11.2 7.2 0.016 14.9 1.6 2.0 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain YrhC PF14143.6 EER25172.1 - 4.5 7.4 5.9 0.78 9.9 0.5 2.5 3 0 0 3 3 3 0 YrhC-like protein Mpv17_PMP22 PF04117.12 EER25173.1 - 8.4e-12 45.1 1.2 8.1e-11 42.0 1.0 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family CKAP2_C PF15297.6 EER25173.1 - 0.14 11.2 0.1 0.26 10.3 0.0 1.4 2 0 0 2 2 2 0 Cytoskeleton-associated protein 2 C-terminus PEX11 PF05648.14 EER25174.1 - 2.3e-12 46.8 1.2 4.2e-12 46.0 0.8 1.5 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) LAT PF15234.6 EER25175.1 - 0.015 15.1 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells SAP30_Sin3_bdg PF13867.6 EER25176.1 - 0.065 13.6 0.4 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 AAA PF00004.29 EER25178.1 - 8.1e-96 317.5 0.0 1.3e-46 158.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER25178.1 - 7.4e-24 83.3 4.1 1.1e-12 47.5 0.3 3.2 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EER25178.1 - 9.6e-18 64.1 1.5 1.9e-17 63.2 0.6 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EER25178.1 - 7.7e-14 52.2 0.0 1.4e-07 31.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EER25178.1 - 1.8e-13 50.6 0.1 2.7e-05 24.0 0.0 3.3 4 1 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EER25178.1 - 3.1e-12 46.9 0.0 1.3e-05 25.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EER25178.1 - 3.3e-11 43.8 0.0 0.00027 21.4 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EER25178.1 - 1.3e-10 41.4 0.4 3.7e-05 23.7 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EER25178.1 - 5.9e-09 36.3 0.4 0.053 13.8 0.0 4.2 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.13 EER25178.1 - 7.6e-09 35.2 0.1 0.0017 17.7 0.0 2.7 2 1 0 2 2 2 2 TIP49 P-loop domain CDC48_2 PF02933.17 EER25178.1 - 4.8e-08 32.7 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 IstB_IS21 PF01695.17 EER25178.1 - 3.1e-07 30.3 0.0 0.02 14.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 EER25178.1 - 4.3e-07 29.5 0.4 0.033 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EER25178.1 - 9.6e-07 29.4 0.0 0.054 14.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EER25178.1 - 1e-06 28.8 0.0 0.02 14.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EER25178.1 - 2.1e-06 28.1 0.0 0.031 14.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase Vps4_C PF09336.10 EER25178.1 - 3.2e-06 27.1 0.2 3.3e-05 23.8 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ATPase PF06745.13 EER25178.1 - 4.4e-06 26.2 0.5 0.68 9.2 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 EER25178.1 - 6e-06 25.9 0.1 0.03 13.8 0.0 3.0 2 2 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 EER25178.1 - 1.6e-05 24.6 4.8 0.46 10.0 0.1 4.7 3 2 2 5 5 5 1 AAA domain AAA_28 PF13521.6 EER25178.1 - 1.7e-05 25.1 0.1 0.31 11.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.13 EER25178.1 - 4.3e-05 22.8 0.0 0.012 14.8 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EER25178.1 - 6.5e-05 22.7 0.1 0.67 9.6 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EER25178.1 - 6.7e-05 23.4 0.0 0.27 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 EER25178.1 - 8.2e-05 22.4 0.0 0.67 9.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain PhoH PF02562.16 EER25178.1 - 8.4e-05 22.1 0.4 0.35 10.3 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.17 EER25178.1 - 9.5e-05 21.6 0.1 0.1 11.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EER25178.1 - 0.00031 20.6 0.0 1.3 8.8 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_17 PF13207.6 EER25178.1 - 0.00035 21.0 0.1 0.87 10.0 0.0 3.3 4 0 0 4 4 2 1 AAA domain ResIII PF04851.15 EER25178.1 - 0.00046 20.2 0.0 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 EER25178.1 - 0.00059 19.8 0.0 0.66 10.0 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EER25178.1 - 0.00061 19.7 0.1 0.67 9.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_3 PF07726.11 EER25178.1 - 0.00073 19.4 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EER25178.1 - 0.0019 17.5 0.0 0.85 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EER25178.1 - 0.004 16.9 0.6 2.6 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EER25178.1 - 0.0067 16.4 0.0 11 5.8 0.0 3.5 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 EER25178.1 - 0.0069 16.2 0.0 0.66 9.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EER25178.1 - 0.007 16.3 0.1 1.7 8.5 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_19 PF13245.6 EER25178.1 - 0.0076 16.6 1.1 6.9 7.0 0.0 3.4 3 1 0 4 4 2 0 AAA domain Zeta_toxin PF06414.12 EER25178.1 - 0.017 14.4 0.5 6.2 6.0 0.0 2.9 3 0 0 3 3 2 0 Zeta toxin KAP_NTPase PF07693.14 EER25178.1 - 0.021 14.1 0.0 0.92 8.7 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.15 EER25178.1 - 0.022 14.7 0.8 4.1 7.3 0.0 3.8 4 0 0 4 4 3 0 NTPase NB-ARC PF00931.22 EER25178.1 - 0.023 13.9 0.0 1.9 7.6 0.0 2.7 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activ_2 PF14532.6 EER25178.1 - 0.023 14.8 0.0 3.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 EER25178.1 - 0.029 13.7 0.1 2.3 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UFD1 PF03152.14 EER25178.1 - 0.047 13.2 0.0 0.32 10.4 0.0 2.1 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin2 PF13189.6 EER25178.1 - 0.074 13.2 0.0 3.3 7.8 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family Zot PF05707.12 EER25178.1 - 0.083 12.5 0.1 9.2 5.8 0.0 3.4 2 2 0 3 3 3 0 Zonular occludens toxin (Zot) T2SSE PF00437.20 EER25178.1 - 0.093 11.8 0.0 3.5 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_6 PF12774.7 EER25178.1 - 0.11 11.4 0.1 11 4.9 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region eIF-1a PF01176.19 EER25178.1 - 0.12 12.3 0.8 3 7.7 0.2 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 EnY2 PF10163.9 EER25179.1 - 0.00054 20.3 1.1 0.0007 19.9 0.0 1.7 2 0 0 2 2 2 1 Transcription factor e(y)2 Peptidase_S49_N PF08496.10 EER25179.1 - 0.068 13.2 4.7 0.12 12.4 4.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SAPS PF04499.15 EER25179.1 - 0.099 11.4 6.5 0.15 10.8 6.5 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SRP-alpha_N PF04086.13 EER25179.1 - 1.5 8.6 23.0 0.091 12.7 18.0 1.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SLC12 PF03522.15 EER25179.1 - 1.6 7.7 6.1 2.1 7.3 6.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EER25179.1 - 2.2 6.9 9.6 2.6 6.7 9.6 1.3 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 EER25179.1 - 3.7 5.4 12.8 5.5 4.8 12.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Raftlin PF15250.6 EER25179.1 - 4.4 6.0 10.0 8.2 5.1 10.0 1.5 1 0 0 1 1 1 0 Raftlin Hamartin PF04388.12 EER25179.1 - 8.4 4.9 11.6 11 4.5 11.6 1.1 1 0 0 1 1 1 0 Hamartin protein F-box PF00646.33 EER25180.1 - 0.014 15.2 0.4 0.082 12.8 0.0 2.4 3 0 0 3 3 3 0 F-box domain F-box_4 PF15966.5 EER25180.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 F-box DnaJ_CXXCXGXG PF00684.19 EER25180.1 - 0.99 9.8 8.7 2 8.8 1.3 2.5 2 0 0 2 2 2 0 DnaJ central domain SAM_2 PF07647.17 EER25181.1 - 2.1e-13 50.2 0.0 3.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EER25181.1 - 6.4e-13 49.0 0.0 9.6e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EER25181.1 - 1.8e-12 47.7 0.0 3.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_4 PF18017.1 EER25181.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Cullin_binding PF03556.15 EER25182.1 - 7.7e-29 100.6 0.9 1.1e-28 100.1 0.9 1.2 1 0 0 1 1 1 1 Cullin binding Cas_CT1975 PF09344.10 EER25183.1 - 1.3 8.4 6.9 1.5 8.2 6.9 1.2 1 0 0 1 1 1 0 CT1975-like protein GNAT_acetyltr_2 PF13718.6 EER25183.1 - 2.1 7.7 5.0 0.65 9.3 2.0 1.8 2 0 0 2 2 2 0 GNAT acetyltransferase 2 SRP-alpha_N PF04086.13 EER25183.1 - 5.3 6.9 17.2 0.09 12.7 8.2 2.0 1 1 1 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 EER25183.1 - 5.8 5.6 5.0 6.5 5.4 5.0 1.1 1 0 0 1 1 1 0 Presenilin UPF0113_N PF17833.1 EER25184.1 - 5.1e-26 91.0 0.0 6.9e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EER25184.1 - 1.1e-23 83.3 0.0 1.6e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 EER25184.1 - 0.02 14.8 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.11 EER25185.1 - 2.9e-28 98.1 2.3 5.3e-28 97.3 0.3 2.5 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 EER25185.1 - 1.5e-26 93.4 0.2 4.4e-25 88.7 0.0 2.4 2 0 0 2 2 2 1 CBF/Mak21 family PIN_12 PF16289.5 EER25185.1 - 0.68 10.4 6.2 0.48 10.9 3.6 2.1 2 0 0 2 2 2 0 PIN domain AMPK1_CBM PF16561.5 EER25187.1 - 7e-08 32.6 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase PAM2 PF07145.15 EER25187.1 - 0.031 14.0 2.7 0.14 11.9 0.2 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region DUF1349 PF07081.11 EER25188.1 - 7.3e-22 77.9 0.0 1.2e-21 77.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) DUF2076 PF09849.9 EER25188.1 - 2.6 8.0 10.7 3.6 7.6 10.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PARG_cat PF05028.14 EER25189.1 - 9e-17 61.4 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Cript PF10235.9 EER25190.1 - 2.5e-26 92.1 9.1 2.5e-26 92.1 9.1 1.8 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EER25190.1 - 0.0021 18.1 13.0 0.014 15.4 7.5 2.6 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 EER25190.1 - 0.0051 17.5 11.3 0.0058 17.3 6.6 2.6 2 1 0 2 2 2 1 zinc-ribbon family zinc_ribbon_2 PF13240.6 EER25190.1 - 0.0094 15.6 10.5 1 9.2 2.5 3.3 3 0 0 3 3 3 2 zinc-ribbon domain zinc-ribbons_6 PF07191.12 EER25190.1 - 0.016 15.1 7.4 0.091 12.8 2.8 2.4 2 0 0 2 2 2 0 zinc-ribbons CEBP_ZZ PF16366.5 EER25190.1 - 0.19 12.0 7.8 0.13 12.5 4.7 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-FLZ PF04570.14 EER25190.1 - 0.23 11.0 10.7 6.9 6.2 0.8 3.3 2 1 1 3 3 3 0 zinc-finger of the FCS-type, C2-C2 zf-HYPF PF07503.12 EER25190.1 - 0.31 10.9 7.0 1.6 8.6 4.1 2.3 2 0 0 2 2 2 0 HypF finger LIM PF00412.22 EER25190.1 - 0.38 11.0 12.0 3.1 8.1 0.1 3.4 2 1 1 3 3 3 0 LIM domain DUF2039 PF10217.9 EER25190.1 - 1.2 9.5 17.6 0.98 9.8 12.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf_UBZ PF18439.1 EER25190.1 - 1.3 8.7 14.5 0.85 9.3 0.2 3.9 3 1 1 4 4 4 0 Ubiquitin-Binding Zinc Finger C1_1 PF00130.22 EER25190.1 - 1.5 8.8 12.2 13 5.8 0.2 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.6 EER25190.1 - 2.4 7.7 9.3 7.7 6.1 2.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 EER25190.1 - 9.5 6.2 13.1 67 3.5 0.1 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MRP-L46 PF11788.8 EER25191.1 - 3.6e-36 124.5 0.2 6.4e-36 123.7 0.2 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 CAF1 PF04857.20 EER25192.1 - 6.3e-76 255.6 0.0 8.3e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 EER25192.1 - 0.021 14.6 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 0 3'-5' exonuclease GARP PF16731.5 EER25193.1 - 0.011 15.5 12.0 0.019 14.7 12.0 1.3 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma ERM PF00769.19 EER25193.1 - 0.034 14.0 17.9 0.072 12.9 17.9 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family LCD1 PF09798.9 EER25193.1 - 0.13 10.7 6.8 0.18 10.3 6.8 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein V_ATPase_I PF01496.19 EER25193.1 - 0.29 9.0 1.1 0.4 8.6 1.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Borrelia_P83 PF05262.11 EER25193.1 - 0.79 8.1 10.0 1.1 7.7 10.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_23 PF13476.6 EER25193.1 - 0.97 9.9 11.7 0.17 12.3 7.8 1.7 2 0 0 2 2 2 0 AAA domain TAF4 PF05236.14 EER25193.1 - 1.2 8.8 19.6 0.012 15.4 11.7 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Presenilin PF01080.17 EER25193.1 - 1.4 7.6 4.6 2.5 6.8 4.6 1.5 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 EER25193.1 - 4.4 6.8 20.1 0.59 9.7 14.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pex26 PF07163.12 EER25193.1 - 4.8 6.4 9.7 17 4.6 6.9 2.8 2 1 0 2 2 2 0 Pex26 protein FUSC PF04632.12 EER25193.1 - 7.1 5.0 6.7 13 4.1 6.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family SBF_like PF13593.6 EER25194.1 - 3.5e-89 299.2 14.7 4.1e-89 299.0 14.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EER25194.1 - 4.9e-14 52.5 1.4 4.9e-14 52.5 1.4 2.0 1 1 1 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 EER25194.1 - 0.00022 19.8 12.1 0.00027 19.5 0.5 2.5 3 0 0 3 3 3 2 Membrane transport protein Mito_carr PF00153.27 EER25195.1 - 1.5e-67 223.5 1.6 5.1e-22 77.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 EER25196.1 - 2.5e-27 95.1 0.0 7.8e-15 54.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein TFB6 PF17110.5 EER25196.1 - 0.31 10.8 0.9 0.51 10.1 0.9 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH PHF5 PF03660.14 EER25197.1 - 4.6e-52 174.6 10.1 5.2e-52 174.4 10.1 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EER25197.1 - 0.16 9.8 5.7 0.018 12.9 2.0 1.2 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EER25197.1 - 1.1 9.4 15.0 2.2 8.4 1.2 3.0 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 EER25198.1 - 2.7e-32 111.6 15.5 2.7e-32 111.6 15.5 2.5 3 0 0 3 3 3 1 pinin/SDK/memA/ protein conserved region Abhydrolase_1 PF00561.20 EER25199.1 - 7.3e-20 71.7 0.1 4.2e-19 69.2 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER25199.1 - 4.3e-17 63.5 0.0 5.5e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER25199.1 - 7.5e-12 45.0 0.0 3.3e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 ESCRT-II PF05871.12 EER25199.1 - 0.051 13.8 0.1 0.081 13.2 0.1 1.3 1 0 0 1 1 1 0 ESCRT-II complex subunit Abhydrolase_4 PF08386.10 EER25199.1 - 0.06 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Sacchrp_dh_NADP PF03435.18 EER25200.1 - 1.7e-19 70.4 0.0 2.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EER25200.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_L37ae PF01780.19 EER25201.1 - 1.7e-41 140.2 10.3 1.9e-41 140.0 10.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EER25201.1 - 0.0018 18.4 1.4 0.0025 17.9 1.4 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_Tnp_IS1595 PF12760.7 EER25201.1 - 0.01 15.8 2.2 0.017 15.1 2.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.15 EER25201.1 - 0.02 14.9 5.0 1.2 9.2 0.3 2.3 1 1 1 2 2 2 0 BED zinc finger DUF1451 PF07295.11 EER25201.1 - 0.044 13.8 0.5 0.06 13.4 0.5 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain PHD PF00628.29 EER25202.1 - 2.6e-08 33.6 9.1 2.6e-08 33.6 9.1 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EER25202.1 - 4e-08 33.4 2.4 4e-08 33.4 2.4 3.6 3 1 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 EER25202.1 - 4.4e-07 29.7 5.0 1.9e-05 24.4 1.7 2.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EER25202.1 - 5.2e-07 29.9 1.0 5.2e-07 29.9 1.0 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EER25202.1 - 3.1e-06 27.0 2.5 3e-05 23.9 0.8 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EER25202.1 - 7e-06 25.8 0.6 7e-06 25.8 0.6 2.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER25202.1 - 7.8e-06 25.6 2.5 7.8e-06 25.6 2.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER25202.1 - 5.4e-05 23.0 1.2 5.4e-05 23.0 1.2 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 EER25202.1 - 0.00021 20.8 4.7 0.00048 19.6 4.7 1.6 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 EER25202.1 - 0.00037 20.5 0.3 0.00037 20.5 0.3 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EER25202.1 - 0.004 17.2 1.5 0.004 17.2 1.5 3.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-Di19 PF05605.12 EER25202.1 - 0.089 13.1 5.4 0.31 11.4 0.0 2.9 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 EER25202.1 - 0.44 10.5 0.1 0.44 10.5 0.1 3.3 3 0 0 3 3 2 0 zinc-finger of a C2HC-type Zn_ribbon_17 PF17120.5 EER25202.1 - 2.2 8.0 7.5 0.4 10.3 1.5 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 EER25202.1 - 2.2 8.3 13.1 0.38 10.7 2.8 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 EER25202.1 - 3.5 7.5 8.4 0.14 12.0 1.3 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain C1_2 PF03107.16 EER25202.1 - 5.1 7.5 9.8 0.16 12.3 1.6 2.6 3 0 0 3 3 3 0 C1 domain MFS_1 PF07690.16 EER25203.1 - 2.4e-36 125.4 42.9 2.4e-36 125.4 42.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Transgly_assoc PF04226.13 EER25203.1 - 1.9 8.8 11.2 9 6.6 4.8 3.3 1 1 1 2 2 2 0 Transglycosylase associated protein HEAT PF02985.22 EER25204.1 - 2.4e-08 33.5 0.5 0.079 13.3 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EER25204.1 - 4.3e-06 27.0 3.8 8.6e-05 22.9 0.4 3.8 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EER25204.1 - 0.00086 19.4 2.6 0.031 14.3 0.2 4.4 5 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EER25204.1 - 0.0027 17.3 0.0 0.7 9.4 0.0 3.1 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 EER25204.1 - 0.2 12.2 6.8 0.55 10.8 0.1 4.4 5 0 0 5 5 5 0 HEAT-like repeat PHD PF00628.29 EER25206.1 - 1.2e-14 53.9 20.7 5.4e-11 42.2 5.8 2.6 2 1 0 2 2 2 2 PHD-finger C1_1 PF00130.22 EER25206.1 - 0.0034 17.2 2.7 0.0034 17.2 2.7 2.9 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prim_Zn_Ribbon PF08273.12 EER25206.1 - 0.11 12.9 3.1 2.4 8.5 0.0 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-PHD-like PF15446.6 EER25206.1 - 0.23 11.1 11.9 0.62 9.7 1.9 3.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 EER25206.1 - 0.36 10.4 8.5 6 6.5 0.4 3.6 3 0 0 3 3 3 0 PHD-finger PHD_4 PF16866.5 EER25206.1 - 7.4 6.7 14.7 2.3 8.4 3.8 3.1 2 1 0 2 2 2 0 PHD-finger Peptidase_M24 PF00557.24 EER25207.1 - 8.5e-08 32.1 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.23 EER25208.1 - 3.7e-07 29.9 0.1 7.1e-07 29.0 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.12 EER25209.1 - 2.4e-66 223.9 0.1 3.4e-65 220.1 0.1 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 INO80_Ies4 PF08193.11 EER25209.1 - 0.00027 21.0 1.2 0.00027 21.0 1.2 3.3 3 1 1 4 4 4 1 INO80 complex subunit Ies4 Lectin_leg-like PF03388.13 EER25210.1 - 4.6e-28 98.1 0.0 7.7e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family HrpB7 PF09486.10 EER25210.1 - 0.0089 16.4 1.1 0.021 15.2 1.1 1.6 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.12 EER25210.1 - 0.038 14.5 3.8 5.3 7.6 0.3 2.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 EER25210.1 - 0.088 13.2 5.6 0.45 10.9 0.9 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 EER25210.1 - 0.46 9.8 7.5 1.6 8.0 7.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Alg6_Alg8 PF03155.15 EER25211.1 - 3.2e-171 570.6 25.7 3.7e-171 570.4 25.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.9 EER25212.1 - 4.9e-23 81.6 0.1 2.2e-21 76.3 0.0 3.3 1 1 1 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EER25212.1 - 1.3e-22 80.1 2.8 2.3e-22 79.3 0.3 2.9 3 0 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EER25212.1 - 6.1e-17 61.7 1.3 1.1e-16 60.9 1.3 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EER25212.1 - 3.8e-09 35.9 0.1 1.2e-08 34.2 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 CtIP_N PF10482.9 EER25212.1 - 0.82 9.7 13.9 0.11 12.5 0.5 3.5 2 1 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Adeno_E1A PF02703.14 EER25212.1 - 1.4 8.4 9.6 0.75 9.3 7.0 1.8 2 0 0 2 2 2 0 Early E1A protein Mito_carr PF00153.27 EER25213.1 - 8e-62 205.2 2.4 1.4e-21 76.2 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EER25213.1 - 0.031 13.4 0.0 6.3 5.9 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Pex2_Pex12 PF04757.14 EER25214.1 - 1.4e-56 191.6 2.8 1.7e-56 191.3 2.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EER25214.1 - 1.9e-06 27.9 2.8 3.4e-06 27.1 2.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EER25214.1 - 0.00021 21.5 2.5 0.00041 20.6 2.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER25214.1 - 0.00025 20.8 3.3 0.00033 20.4 2.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER25214.1 - 0.00085 19.3 3.5 0.00085 19.3 3.5 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EER25214.1 - 0.0023 17.8 1.9 0.004 17.0 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER25214.1 - 0.0039 17.0 2.3 0.0074 16.1 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Auto_anti-p27 PF06677.12 EER25214.1 - 2.2 8.5 5.0 3.8 7.7 5.0 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) RsfS PF02410.15 EER25215.1 - 1.9e-13 50.7 0.0 4.5e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation NMD3 PF04981.13 EER25216.1 - 1.1e-82 277.1 3.7 1.5e-82 276.7 3.7 1.2 1 0 0 1 1 1 1 NMD3 family HypA PF01155.19 EER25216.1 - 0.23 11.5 7.1 5.8 7.0 0.1 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DYW_deaminase PF14432.6 EER25216.1 - 2.6 7.9 4.6 4.5 7.2 1.2 2.7 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases DZR PF12773.7 EER25216.1 - 6.3 6.9 11.1 6.4e+02 0.5 11.1 2.7 1 1 0 1 1 1 0 Double zinc ribbon FYVE PF01363.21 EER25216.1 - 7.1 6.9 7.8 23 5.2 4.1 2.6 2 1 0 2 2 2 0 FYVE zinc finger RRM_1 PF00076.22 EER25217.1 - 0.055 13.3 0.0 0.29 11.0 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_125 PF06824.11 EER25218.1 - 3e-180 599.6 0.0 3.4e-180 599.4 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) FemAB PF02388.16 EER25218.1 - 0.02 13.8 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 FemAB family CDC27 PF09507.10 EER25219.1 - 1.5e-96 324.4 23.8 1.7e-96 324.2 23.8 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C3HC4_2 PF13923.6 EER25220.1 - 4e-10 39.4 16.6 4e-10 39.4 16.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EER25220.1 - 1.6e-07 31.1 7.4 3.2e-07 30.1 7.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 EER25220.1 - 1.4e-06 28.0 13.6 1.4e-06 28.0 13.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER25220.1 - 1.1e-05 25.2 17.5 1.1e-05 25.2 17.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER25220.1 - 2.2e-05 24.4 14.2 2.2e-05 24.4 14.2 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EER25220.1 - 7.9e-05 22.5 16.7 7.9e-05 22.5 16.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EER25220.1 - 0.00033 20.7 15.9 0.00033 20.7 15.9 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EER25220.1 - 0.00059 20.1 16.7 0.00059 20.1 16.7 2.3 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.27 EER25220.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain Prok-RING_4 PF14447.6 EER25220.1 - 0.0042 16.9 16.8 0.58 10.1 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EER25220.1 - 0.0053 16.9 8.8 0.0053 16.9 8.8 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EER25220.1 - 0.008 16.5 8.5 0.008 16.5 8.5 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain DUF1178 PF06676.11 EER25220.1 - 0.0085 16.5 0.0 0.031 14.6 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) Sgf11 PF08209.11 EER25220.1 - 0.016 14.8 0.2 0.016 14.8 0.2 2.4 2 1 1 3 3 3 0 Sgf11 (transcriptional regulation protein) Mob_synth_C PF06463.13 EER25220.1 - 0.023 14.6 3.6 0.063 13.2 3.6 1.7 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C U-box PF04564.15 EER25220.1 - 0.024 14.8 0.0 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 U-box domain Snf7 PF03357.21 EER25221.1 - 1.2e-16 60.9 14.8 1.2e-16 60.9 14.8 1.8 1 1 1 2 2 2 1 Snf7 CompInhib_SCIN PF11546.8 EER25221.1 - 0.23 11.5 5.5 1.1 9.3 5.5 2.2 1 1 0 1 1 1 0 Staphylococcal complement inhibitor SCIN YhhN PF07947.14 EER25222.1 - 4.4e-44 150.3 5.7 6.6e-44 149.7 5.7 1.3 1 0 0 1 1 1 1 YhhN family TRAPPC-Trs85 PF12739.7 EER25223.1 - 1.6e-112 376.5 0.0 4.1e-111 371.8 0.0 2.1 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PolyA_pol PF01743.20 EER25224.1 - 7.2e-22 78.2 0.1 3.3e-21 76.0 0.1 2.1 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EER25224.1 - 1.3e-06 28.1 0.0 4.1e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EER25224.1 - 0.002 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative Tti2 PF10521.9 EER25225.1 - 1.7e-97 326.3 2.2 2.4e-97 325.9 2.2 1.2 1 0 0 1 1 1 1 Tti2 family Syja_N PF02383.18 EER25226.1 - 2.5e-79 266.9 0.1 4e-79 266.2 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Glyco_hydro_47 PF01532.20 EER25227.1 - 7.9e-183 608.5 0.0 9.1e-183 608.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ADH_zinc_N PF00107.26 EER25228.1 - 2.1e-19 69.8 1.8 2.9e-19 69.3 1.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER25228.1 - 4e-11 44.1 0.0 7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER25228.1 - 8.3e-09 35.3 0.5 1e-07 31.8 0.0 2.8 2 2 2 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EER25228.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ELFV_dehydrog PF00208.21 EER25228.1 - 0.11 12.2 1.4 0.24 11.1 1.4 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TPR_12 PF13424.6 EER25229.1 - 1.1e-07 32.1 7.2 0.013 15.8 1.6 4.1 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EER25229.1 - 4.2e-06 26.4 1.1 6.6 7.0 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EER25229.1 - 6.9e-05 22.7 0.0 2.3 8.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EER25229.1 - 0.00021 21.7 7.1 5.7 7.5 0.2 6.1 3 3 3 7 7 7 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EER25229.1 - 0.001 18.5 6.9 0.076 12.4 2.0 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_14 PF13428.6 EER25229.1 - 0.002 18.8 5.9 7.1 7.7 0.3 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 EER25229.1 - 0.0021 18.5 0.1 18 6.3 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EER25229.1 - 0.0037 17.1 1.7 5.9 6.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER25229.1 - 0.094 12.6 0.0 5.4 7.0 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Mur_ligase_M PF08245.12 EER25230.1 - 0.00012 22.2 0.0 0.0021 18.1 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain TPR_12 PF13424.6 EER25231.1 - 6.8e-12 45.5 0.3 0.0035 17.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF676 PF05057.14 EER25231.1 - 3.6e-07 29.9 0.0 9.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_2 PF07719.17 EER25231.1 - 7.5e-07 28.8 0.0 0.026 14.6 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EER25231.1 - 1.3e-06 28.9 0.5 0.15 12.6 0.0 5.0 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EER25231.1 - 3.7e-06 26.6 0.7 0.025 14.6 0.1 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EER25231.1 - 5.5e-06 26.8 0.4 2.3 9.3 0.1 5.4 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EER25231.1 - 1.6e-05 24.6 1.9 0.13 12.2 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EER25231.1 - 0.00013 21.4 0.8 0.038 13.4 0.1 3.2 1 1 2 4 4 4 2 MalT-like TPR region AAA_22 PF13401.6 EER25231.1 - 0.00023 21.4 0.0 0.00061 20.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EER25231.1 - 0.00033 21.1 0.0 0.0013 19.2 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain TPR_4 PF07721.14 EER25231.1 - 0.00095 19.6 0.5 19 6.3 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat PPR PF01535.20 EER25231.1 - 0.0023 18.0 0.0 7.3 7.1 0.0 3.8 3 0 0 3 3 3 1 PPR repeat PGAP1 PF07819.13 EER25231.1 - 0.0032 17.2 0.0 0.007 16.1 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein TPR_1 PF00515.28 EER25231.1 - 0.0068 16.2 0.1 1.9 8.5 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat NB-ARC PF00931.22 EER25231.1 - 0.013 14.7 0.0 0.11 11.6 0.0 2.2 1 1 0 1 1 1 0 NB-ARC domain Abhydrolase_6 PF12697.7 EER25231.1 - 0.022 15.3 0.0 0.16 12.5 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Clathrin PF00637.20 EER25231.1 - 0.027 14.3 0.1 0.85 9.5 0.0 3.1 4 0 0 4 4 4 0 Region in Clathrin and VPS TPR_16 PF13432.6 EER25231.1 - 0.032 14.9 0.2 8 7.2 0.0 3.9 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EER25231.1 - 0.06 13.6 0.0 1.5 9.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EER25231.1 - 0.11 13.2 0.6 2.5 8.9 0.0 3.5 5 0 0 5 5 2 0 Tetratricopeptide repeat Helo_like_N PF17111.5 EER25232.1 - 9.8e-11 41.4 0.9 1.5e-10 40.8 0.9 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins FYVE PF01363.21 EER25232.1 - 0.0018 18.4 0.3 0.0035 17.4 0.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger zinc_ribbon_4 PF13717.6 EER25232.1 - 0.15 12.0 4.2 2.4 8.1 3.8 2.6 1 1 1 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.6 EER25232.1 - 0.29 11.1 3.3 0.55 10.2 3.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 OrfB_Zn_ribbon PF07282.11 EER25232.1 - 0.59 10.1 2.7 1.5 8.8 2.7 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain HypA PF01155.19 EER25232.1 - 0.9 9.6 7.0 0.3 11.1 3.5 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA IBR PF01485.21 EER25232.1 - 1.9 8.8 5.6 5.6 7.3 5.6 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 EER25233.1 - 1.8e-31 109.5 0.0 3.1e-12 46.4 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EER25233.1 - 4.6e-14 52.3 0.0 6.5e-06 25.6 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Fungal_trans_2 PF11951.8 EER25234.1 - 2.3e-10 39.9 2.1 4.3e-10 39.0 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER25234.1 - 5.2e-10 39.3 8.5 9.4e-10 38.5 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 EER25235.1 - 6.1e-44 150.9 5.8 8e-44 150.6 5.8 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase DNA_pol_B PF00136.21 EER25236.1 - 4.7e-150 500.3 4.0 6.4e-150 499.8 4.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EER25236.1 - 3.2e-80 269.8 0.0 6.1e-80 268.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EER25236.1 - 1.2e-17 64.1 7.2 3e-17 62.9 7.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 EER25236.1 - 0.0011 18.7 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EER25236.1 - 0.0016 18.4 0.2 0.013 15.5 0.2 2.4 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 EER25236.1 - 0.013 14.3 0.3 0.081 11.8 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral ETC_C1_NDUFA5 PF04716.14 EER25236.1 - 0.09 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 ETC complex I subunit conserved region PAS_4 PF08448.10 EER25238.1 - 0.036 14.3 0.4 0.061 13.6 0.4 1.3 1 0 0 1 1 1 0 PAS fold zf-C2H2_4 PF13894.6 EER25239.1 - 1.7e-08 34.6 13.3 0.15 13.0 0.0 5.4 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 EER25239.1 - 2.2e-08 34.1 14.6 0.057 13.9 0.3 5.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EER25239.1 - 6.7e-06 26.0 7.6 0.13 12.2 0.0 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER25239.1 - 0.001 19.3 11.5 1.6 9.1 0.1 5.4 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER25239.1 - 0.0015 18.9 1.7 44 4.7 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 EER25239.1 - 0.016 15.3 6.2 0.098 12.8 1.7 2.7 2 0 0 2 2 2 0 Zinc ribbon domain Rad50_zn_hook PF04423.14 EER25239.1 - 0.024 14.5 0.0 0.1 12.5 0.0 2.0 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-C2H2_2 PF12756.7 EER25239.1 - 0.026 14.9 8.9 5.5 7.4 1.0 3.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Cytochrom_CIII PF02085.16 EER25239.1 - 0.03 14.7 9.9 0.058 13.7 9.9 1.5 1 0 0 1 1 1 0 Class III cytochrome C family Prim_Zn_Ribbon PF08273.12 EER25239.1 - 0.037 14.3 0.5 2.2 8.6 0.1 2.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DZR PF12773.7 EER25239.1 - 0.073 13.1 6.0 4.8 7.3 6.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon DUF4187 PF13821.6 EER25239.1 - 0.16 11.7 2.9 13 5.6 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) zf-nanos PF05741.13 EER25239.1 - 0.3 11.3 5.7 0.34 11.2 0.3 3.3 2 1 1 3 3 3 0 Nanos RNA binding domain zf-C2H2_8 PF15909.5 EER25239.1 - 1.3 9.4 6.3 1.3 9.3 1.6 2.7 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 EER25239.1 - 2.4 8.4 5.2 38 4.5 0.0 3.4 3 0 0 3 3 3 0 Zic proteins zinc finger domain Cyanate_lyase PF02560.14 EER25240.1 - 3.1e-29 100.6 0.0 4.4e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.6 EER25240.1 - 0.0084 16.4 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain AP_endonuc_2 PF01261.24 EER25241.1 - 3.9e-39 134.3 0.0 5.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Pentapeptide_4 PF13599.6 EER25242.1 - 2.1e-08 34.2 0.1 0.0055 16.8 0.0 3.2 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 EER25242.1 - 8.7e-06 25.3 0.0 0.0054 16.3 0.0 2.9 3 0 0 3 3 3 2 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 EER25242.1 - 0.0017 18.5 0.8 20 5.4 0.0 4.1 2 1 3 5 5 5 3 Pentapeptide repeats (9 copies) PLDc_2 PF13091.6 EER25243.1 - 1.6e-14 54.0 0.0 3.3e-06 27.0 0.0 3.9 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EER25243.1 - 1.1e-12 47.6 1.6 1.8e-06 27.8 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif SPT_ssu-like PF11779.8 EER25244.1 - 5.3e-17 61.2 3.5 5.3e-17 61.2 3.5 1.6 2 0 0 2 2 2 1 Small subunit of serine palmitoyltransferase-like Kinetochor_Ybp2 PF08568.10 EER25245.1 - 2.4e-119 399.6 0.0 2.8e-119 399.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Rhomboid PF01694.22 EER25247.1 - 7.8e-33 113.6 10.3 7.8e-33 113.6 10.3 2.4 3 0 0 3 3 3 1 Rhomboid family GST_N_3 PF13417.6 EER25248.1 - 0.00013 22.3 0.0 0.00028 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EER25248.1 - 0.00026 21.2 0.3 0.00084 19.6 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EER25248.1 - 0.0015 18.5 0.1 0.0034 17.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EER25248.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EER25248.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DHHC PF01529.20 EER25249.1 - 3.3e-38 130.8 11.5 3.3e-38 130.8 11.5 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1461 PF07314.11 EER25249.1 - 1.2 9.0 3.4 2.6 7.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) UQ_con PF00179.26 EER25250.1 - 5.5e-18 65.0 0.0 8.3e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Adeno_E3 PF06040.11 EER25250.1 - 0.01 16.0 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E3 protein Glycoprotein PF03409.15 EER25250.1 - 0.058 12.2 0.9 0.075 11.9 0.9 1.1 1 0 0 1 1 1 0 Transmembrane glycoprotein RNase_PH PF01138.21 EER25250.1 - 0.081 13.4 0.4 0.13 12.7 0.4 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 RRM_1 PF00076.22 EER25251.1 - 1.7e-14 53.4 0.2 5.1e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC66 PF15236.6 EER25251.1 - 0.43 10.4 18.7 0.68 9.8 18.7 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF2514 PF10721.9 EER25251.1 - 2.2 8.3 12.3 3.9 7.5 12.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ISG65-75 PF11727.8 EER25251.1 - 2.5 7.3 12.3 3.6 6.7 12.3 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Borrelia_P83 PF05262.11 EER25251.1 - 8.1 4.8 10.7 10 4.4 10.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein MP PF01107.18 EER25252.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Viral movement protein (MP) Bacteriocin_IIc PF10439.9 EER25252.1 - 9 6.5 8.4 25 5.1 0.7 2.5 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Fmp27 PF10344.9 EER25254.1 - 7e-197 656.4 0.0 1.7e-196 655.1 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EER25254.1 - 5.6e-196 652.0 0.5 5.6e-196 652.0 0.5 2.9 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EER25254.1 - 1.9e-174 581.1 0.5 3.5e-174 580.2 0.5 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EER25254.1 - 7.2e-57 191.6 0.6 1.6e-56 190.5 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 EER25254.1 - 1.1e-55 188.1 0.0 2.2e-55 187.0 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 EER25254.1 - 1e-28 100.0 0.0 6.9e-28 97.4 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Serine_rich PF08824.10 EER25254.1 - 0.03 14.3 0.1 0.095 12.7 0.1 1.8 1 0 0 1 1 1 0 Serine rich protein interaction domain Herpes_UL14 PF03580.14 EER25254.1 - 8 6.7 7.9 31 4.8 0.4 3.5 3 0 0 3 3 3 0 Herpesvirus UL14-like protein SnAC PF14619.6 EER25254.1 - 8.1 7.1 7.7 4 8.1 3.7 2.6 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex B-block_TFIIIC PF04182.12 EER25256.1 - 3.5e-20 71.9 0.1 8e-20 70.8 0.1 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.22 EER25256.1 - 0.011 15.6 0.4 0.29 11.1 0.0 2.8 2 0 0 2 2 2 0 MarR family MarR_2 PF12802.7 EER25256.1 - 0.021 14.7 0.2 0.46 10.4 0.0 2.9 2 0 0 2 2 2 0 MarR family HTH_36 PF13730.6 EER25256.1 - 0.081 12.9 0.0 2.2 8.3 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain tRNA-synt_1c PF00749.21 EER25257.1 - 3.8e-92 308.5 0.0 5.5e-92 308.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ_C PF01556.18 EER25258.1 - 1.4e-38 132.3 0.1 2.2e-38 131.7 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EER25258.1 - 6e-20 71.1 1.9 1e-19 70.4 1.9 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EER25258.1 - 1.7e-13 50.7 16.8 2.9e-13 50.0 16.8 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EER25258.1 - 0.012 15.5 9.1 0.054 13.5 0.6 2.6 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HicA_toxin PF07927.12 EER25258.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, HypA PF01155.19 EER25258.1 - 0.33 11.0 6.8 1.4 9.0 1.5 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 EER25258.1 - 0.99 9.6 6.9 4.2 7.6 1.2 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 RseC_MucC PF04246.12 EER25258.1 - 8.2 6.4 7.0 0.38 10.7 0.6 2.0 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC 4HBT PF03061.22 EER25259.1 - 9.9e-10 38.6 0.0 1.7e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EER25259.1 - 1.8e-05 24.2 0.2 2.7e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.6 EER25259.1 - 0.00017 22.1 0.0 0.00022 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily PseudoU_synth_2 PF00849.22 EER25260.1 - 6.6e-26 91.3 0.0 1.1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 EER25260.1 - 0.0077 15.9 0.1 0.016 14.9 0.1 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_L32e PF01655.18 EER25261.1 - 2.5e-48 163.0 0.9 2.5e-48 163.0 0.9 1.8 2 0 0 2 2 2 1 Ribosomal protein L32 Meleagrin PF08189.11 EER25261.1 - 0.05 13.3 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Meleagrin/Cygnin family Sec2p PF06428.11 EER25262.1 - 3.9e-11 42.8 9.4 3.9e-11 42.8 9.4 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p PspA_IM30 PF04012.12 EER25262.1 - 0.00013 21.6 15.5 0.00018 21.2 0.2 2.1 2 0 0 2 2 2 1 PspA/IM30 family Jnk-SapK_ap_N PF09744.9 EER25262.1 - 0.0015 18.8 17.1 0.094 12.9 9.9 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 SlyX PF04102.12 EER25262.1 - 0.0032 18.1 9.4 0.16 12.6 0.0 3.3 2 1 1 3 3 3 1 SlyX Cluap1 PF10234.9 EER25262.1 - 0.0069 15.8 5.5 0.0069 15.8 5.5 1.9 2 0 0 2 2 2 1 Clusterin-associated protein-1 GOLGA2L5 PF15070.6 EER25262.1 - 0.021 13.5 6.8 0.037 12.7 0.0 2.1 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 DUF4407 PF14362.6 EER25262.1 - 0.028 13.8 10.2 0.68 9.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1682 PF07946.14 EER25262.1 - 0.075 12.2 3.9 0.12 11.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) LMBR1 PF04791.16 EER25262.1 - 0.086 11.7 0.3 0.11 11.4 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Rop-like PF05082.13 EER25262.1 - 0.13 12.1 3.1 3 7.7 0.1 2.6 2 0 0 2 2 2 0 Rop-like ATG16 PF08614.11 EER25262.1 - 0.15 12.3 25.1 0.49 10.6 15.0 2.2 1 1 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EER25262.1 - 0.25 11.9 14.9 3 8.4 0.0 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 EER25262.1 - 0.3 11.3 3.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family TFIIA PF03153.13 EER25262.1 - 0.37 10.7 7.1 0.44 10.5 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nsp1_C PF05064.13 EER25262.1 - 0.41 10.5 7.9 1.4 8.8 0.5 2.6 2 1 1 3 3 3 0 Nsp1-like C-terminal region DUF16 PF01519.16 EER25262.1 - 0.47 11.0 5.5 6.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 HrpB7 PF09486.10 EER25262.1 - 0.78 10.1 21.1 1.3 9.4 1.2 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) YlqD PF11068.8 EER25262.1 - 0.87 10.0 9.6 0.41 11.0 3.6 2.2 2 0 0 2 2 2 0 YlqD protein bZIP_1 PF00170.21 EER25262.1 - 1.1 9.4 13.2 2.7 8.1 0.2 3.1 2 1 1 3 3 3 0 bZIP transcription factor FAM76 PF16046.5 EER25262.1 - 1.2 8.5 5.5 0.47 9.8 0.8 2.0 2 0 0 2 2 2 0 FAM76 protein ADIP PF11559.8 EER25262.1 - 1.3 9.1 18.7 0.9 9.6 8.8 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 EER25262.1 - 1.5 8.5 11.2 3.4 7.4 6.8 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CLZ PF16526.5 EER25262.1 - 1.6 9.1 17.5 2.1 8.8 0.2 2.8 3 0 0 3 3 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 EER25262.1 - 2.1 7.2 15.7 2 7.2 6.8 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 EER25262.1 - 2.2 8.0 7.1 12 5.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) AAA_13 PF13166.6 EER25262.1 - 2.3 6.8 8.0 5.8 5.4 0.5 2.1 2 0 0 2 2 2 0 AAA domain PP2C_C PF07830.13 EER25262.1 - 3.2 8.3 7.8 30 5.2 0.0 3.2 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Exonuc_VII_L PF02601.15 EER25262.1 - 4.9 6.6 15.0 78 2.7 15.2 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Lebercilin PF15619.6 EER25262.1 - 5.6 6.6 22.0 12 5.5 14.9 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Atg14 PF10186.9 EER25262.1 - 5.9 5.9 13.5 1.8 7.6 0.2 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 EER25262.1 - 9.9 3.5 17.3 2.2 5.7 9.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) MAP65_ASE1 PF03999.12 EER25263.1 - 6.8e-78 262.9 7.0 7.1e-77 259.5 2.6 2.3 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) BAR_3 PF16746.5 EER25263.1 - 0.08 12.6 0.8 4.5 6.9 0.2 2.6 2 0 0 2 2 2 0 BAR domain of APPL family VGPC1_C PF16799.5 EER25263.1 - 0.85 9.6 4.8 18 5.4 0.3 3.2 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 JAB PF01398.21 EER25264.1 - 1.6e-29 102.3 0.8 2.3e-29 101.8 0.1 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EER25264.1 - 8.1e-23 81.2 0.7 1.7e-22 80.1 0.7 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EER25264.1 - 0.00023 20.9 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EER25264.1 - 0.076 13.1 0.1 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Phospholamban PF04272.14 EER25265.1 - 0.45 10.0 6.9 8.1 6.0 2.6 2.8 2 0 0 2 2 2 0 Phospholamban CRCB PF02537.15 EER25266.1 - 3e-37 126.8 17.9 8.7e-22 77.3 10.3 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Prion_bPrPp PF11587.8 EER25266.1 - 3.5 7.5 6.1 0.75 9.7 1.8 2.1 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal UPRTase PF14681.6 EER25267.1 - 4.2e-74 248.5 0.0 4.7e-74 248.3 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EER25267.1 - 1.4e-07 31.1 0.0 2.1e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.17 EER25267.1 - 0.067 12.5 0.1 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase Fungal_trans PF04082.18 EER25268.1 - 1.4e-17 63.6 1.9 2.4e-17 62.8 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EER25268.1 - 3.9e-07 30.2 12.3 7.9e-05 22.9 5.5 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EER25268.1 - 0.0011 19.3 14.3 0.04 14.4 5.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER25268.1 - 0.0018 18.9 12.6 0.27 12.2 4.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EER25268.1 - 0.0078 16.9 0.6 0.52 11.0 0.0 2.5 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 EER25268.1 - 0.37 11.1 3.7 1.4 9.3 3.7 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RasGEF PF00617.19 EER25269.1 - 1.9e-59 200.8 0.2 3.1e-59 200.1 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EER25269.1 - 4.6e-27 94.3 0.2 1.2e-26 93.0 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EER25269.1 - 8.5e-15 54.1 0.1 2e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER25269.1 - 9.4e-12 44.6 0.1 2.2e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EER25269.1 - 3.7e-11 42.5 0.1 8.1e-11 41.4 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EER25269.1 - 0.0052 16.8 0.0 0.016 15.3 0.0 1.8 1 0 0 1 1 1 1 WW domain DegS PF05384.11 EER25269.1 - 0.19 11.2 0.2 3 7.3 0.0 2.4 2 0 0 2 2 2 0 Sensor protein DegS Peptidase_S28 PF05577.12 EER25270.1 - 2.7e-52 178.0 3.1 1e-50 172.8 4.3 2.5 2 1 0 2 2 2 1 Serine carboxypeptidase S28 FAD_binding_4 PF01565.23 EER25271.1 - 7e-18 64.7 0.0 1.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cytokin-bind PF09265.10 EER25271.1 - 0.081 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding KRE1 PF17056.5 EER25272.1 - 1.5e-08 34.2 0.2 2.4e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 RNA_pol_Rpc4 PF05132.14 EER25273.1 - 5e-34 117.9 0.0 5e-34 117.9 0.0 3.5 3 2 0 3 3 3 1 RNA polymerase III RPC4 BSP_II PF05432.11 EER25273.1 - 1.3 8.7 13.8 0.73 9.5 10.9 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Zn_clus PF00172.18 EER25274.1 - 0.0014 18.7 12.7 0.0027 17.8 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.23 EER25275.1 - 3.7e-45 152.8 0.3 6.5e-45 152.0 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EER25275.1 - 5.9e-35 119.9 0.1 1.9e-34 118.3 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF4687 PF15747.5 EER25275.1 - 0.65 10.5 5.1 0.13 12.8 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4687) DcpS_C PF11969.8 EER25276.1 - 3.6e-19 69.3 2.8 2.7e-18 66.5 2.8 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 EER25276.1 - 3.6e-19 68.9 0.1 1.2e-18 67.3 0.1 1.9 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 EER25276.1 - 1.7e-14 54.3 2.6 7.5e-14 52.3 2.6 1.9 1 1 0 1 1 1 1 HIT domain SIP1 PF04938.12 EER25276.1 - 0.03 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) OB_NTP_bind PF07717.16 EER25277.1 - 4.5e-16 59.0 0.0 9.2e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EER25277.1 - 1.4e-14 54.2 0.2 7.3e-14 52.0 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EER25277.1 - 1.7e-14 54.1 0.0 3.9e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 EER25277.1 - 1.7e-10 41.2 1.0 3.7e-10 40.1 1.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 EER25277.1 - 2.4e-08 33.9 0.2 4.5e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 EER25277.1 - 0.0035 16.4 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein CoA_trans PF01144.23 EER25277.1 - 0.0041 16.5 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 Coenzyme A transferase PhoH PF02562.16 EER25277.1 - 0.019 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 EER25277.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 EER25277.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain dsRBD2 PF17842.1 EER25277.1 - 0.057 13.6 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 DND1_DSRM PF14709.7 EER25277.1 - 0.082 13.2 0.3 0.23 11.7 0.3 1.8 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_30 PF13604.6 EER25277.1 - 0.16 11.7 3.2 0.2 11.3 0.3 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EER25277.1 - 0.28 11.5 1.4 1.9 8.7 1.4 2.3 1 1 0 1 1 1 0 AAA domain HATPase_c PF02518.26 EER25278.1 - 8.1e-19 68.2 0.0 1.5e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EER25278.1 - 1.9e-14 53.8 0.1 0.00022 21.4 0.0 3.5 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.25 EER25278.1 - 3.7e-05 23.7 0.1 0.0001 22.2 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Ribosomal_L36e PF01158.18 EER25279.1 - 2.9e-40 136.4 6.5 3.2e-40 136.3 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e PBS_linker_poly PF00427.21 EER25279.1 - 0.013 15.6 0.4 0.014 15.4 0.4 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide DUF2207 PF09972.9 EER25279.1 - 0.067 11.9 0.1 0.071 11.9 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MRP-L28 PF09812.9 EER25279.1 - 0.2 11.8 2.5 0.24 11.5 2.5 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 TUG-UBL1 PF11470.8 EER25280.1 - 1e-24 86.5 0.0 3.4e-24 84.8 0.0 2.0 1 0 0 1 1 1 1 TUG ubiquitin-like domain UBX PF00789.20 EER25280.1 - 1.1e-05 25.6 0.0 8.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 UBX domain RBD PF02196.15 EER25280.1 - 0.13 12.4 0.0 0.46 10.6 0.0 1.9 1 0 0 1 1 1 0 Raf-like Ras-binding domain Proteasome PF00227.26 EER25281.1 - 2.3e-39 134.9 0.0 2.6e-39 134.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NatB_MDM20 PF09797.9 EER25282.1 - 3e-108 362.2 3.3 3.4e-108 362.0 0.7 2.2 3 0 0 3 3 3 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EER25282.1 - 1.4e-05 25.5 8.2 0.0014 19.1 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Methyltransf_2 PF00891.18 EER25285.1 - 6e-24 84.5 0.1 1.2e-23 83.6 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation PF08100.11 EER25285.1 - 0.00015 21.7 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.7 EER25285.1 - 0.0013 18.5 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_5 PF01022.20 EER25285.1 - 0.0048 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Dimerisation2 PF16864.5 EER25285.1 - 0.0071 16.3 0.0 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 Dimerisation domain Rrf2 PF02082.20 EER25285.1 - 0.024 15.0 0.0 0.19 12.1 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator MarR PF01047.22 EER25285.1 - 0.033 14.1 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.6 EER25285.1 - 0.084 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_IclR PF09339.10 EER25285.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_25 PF13649.6 EER25285.1 - 0.15 12.8 0.0 1 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain AT_hook PF02178.19 EER25285.1 - 0.34 10.9 2.8 1.1 9.3 2.8 1.9 1 0 0 1 1 1 0 AT hook motif zf-RING_2 PF13639.6 EER25286.1 - 4e-05 23.9 7.3 4e-05 23.9 7.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EER25286.1 - 6.2e-05 22.8 6.0 6.2e-05 22.8 6.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EER25286.1 - 0.00024 21.2 7.6 0.00024 21.2 7.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EER25286.1 - 0.00052 19.8 7.5 0.00052 19.8 7.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER25286.1 - 0.00058 19.8 6.6 0.0016 18.4 6.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EER25286.1 - 0.00063 19.7 7.1 0.00063 19.7 7.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EER25286.1 - 0.0013 18.5 4.1 0.0013 18.5 4.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EER25286.1 - 0.21 11.5 7.3 0.11 12.4 2.2 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.7 EER25286.1 - 0.31 11.1 11.4 0.7 10.0 5.5 3.1 1 1 1 2 2 2 0 Double zinc ribbon zf-ANAPC11 PF12861.7 EER25286.1 - 3 7.9 7.0 0.26 11.4 1.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EER25286.1 - 4 7.4 8.6 2.5 8.1 4.7 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.32 EER25287.1 - 1.8e-20 72.8 9.9 5.1e-06 27.1 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25287.1 - 0.0099 16.2 0.0 0.18 12.1 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER25287.1 - 0.012 14.3 1.9 4 6.0 0.0 3.8 2 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EER25287.1 - 0.034 13.5 0.0 0.28 10.5 0.0 2.0 1 1 0 2 2 2 0 WD40-like domain PGA2 PF07543.12 EER25287.1 - 1.1 9.2 9.2 1.8 8.5 9.2 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Pox_Ag35 PF03286.14 EER25287.1 - 8.3 6.1 12.0 0.4 10.5 5.6 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Proteasome PF00227.26 EER25288.1 - 1.2e-38 132.5 0.0 1.4e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.29 EER25289.1 - 8.2e-22 77.9 0.0 2.7e-21 76.2 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EER25289.1 - 3.3e-12 46.5 0.1 5.6e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EER25289.1 - 0.031 13.9 0.1 0.058 13.0 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 EER25291.1 - 3e-53 176.6 16.6 1.3e-05 25.8 0.0 13.1 13 3 0 13 13 13 10 WD domain, G-beta repeat Utp13 PF08625.11 EER25291.1 - 8.4e-51 171.6 0.1 1.3e-50 171.0 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EER25291.1 - 2.4e-11 43.8 1.2 0.69 10.2 0.0 7.8 6 2 1 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER25291.1 - 3.8e-05 22.5 0.7 1.5 7.4 0.1 4.5 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EER25291.1 - 0.00063 18.6 3.0 2 7.1 0.1 4.4 4 1 0 4 4 4 2 Nup133 N terminal like Ge1_WD40 PF16529.5 EER25291.1 - 0.0036 16.3 0.4 0.67 8.9 0.0 3.6 5 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein G-patch_2 PF12656.7 EER25292.1 - 3.9e-22 78.1 0.1 3.9e-22 78.1 0.1 2.6 2 1 0 2 2 2 1 G-patch domain G-patch PF01585.23 EER25292.1 - 0.0021 17.9 1.4 0.0039 17.1 0.3 2.1 2 0 0 2 2 2 1 G-patch domain Phage_XkdX PF09693.10 EER25292.1 - 0.39 10.8 2.2 0.75 9.9 2.2 1.4 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Myb_DNA-bind_6 PF13921.6 EER25293.1 - 1.2e-16 60.7 0.0 1.2e-16 60.7 0.0 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain HSA PF07529.13 EER25293.1 - 1.5e-12 47.7 0.1 1.5e-12 47.7 0.1 3.4 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 EER25293.1 - 7.7e-05 22.8 0.7 0.0002 21.5 0.7 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.32 EER25294.1 - 2.3e-08 34.6 0.0 4.5 8.3 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25294.1 - 0.026 14.8 0.0 30 5.0 0.0 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M48_N PF16491.5 EER25295.1 - 9.8e-67 224.4 8.9 9.8e-67 224.4 8.9 1.6 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EER25295.1 - 1.3e-46 158.8 0.0 2.7e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EER25295.1 - 0.0013 18.0 0.9 0.0019 17.5 0.2 1.5 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.6 EER25295.1 - 0.0072 16.0 0.8 0.023 14.4 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) eIF2_C PF09173.11 EER25297.1 - 1.1e-34 118.5 0.2 2.4e-34 117.4 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EER25297.1 - 5.2e-24 84.9 0.1 3.8e-23 82.0 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EER25297.1 - 1.1e-10 41.8 0.1 2.4e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EER25297.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER25297.1 - 0.0049 16.8 0.1 0.062 13.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EER25297.1 - 0.15 12.1 0.0 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Peptidase_M16_C PF05193.21 EER25298.1 - 2.2e-20 73.4 0.0 1.1e-15 58.1 0.0 2.7 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EER25298.1 - 0.00043 20.3 0.0 0.0012 18.8 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 EER25298.1 - 0.64 9.1 5.4 4.6 6.3 5.4 2.2 1 1 0 1 1 1 0 Peptidase M16C associated Dsl1_C PF11989.8 EER25299.1 - 4.7e-07 29.7 0.0 1.5e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.13 EER25299.1 - 9e-07 27.8 3.2 0.0037 15.9 0.7 3.9 3 1 1 4 4 4 3 Centromere/kinetochore Zw10 Seryl_tRNA_N PF02403.22 EER25299.1 - 0.014 15.6 4.0 2.4 8.4 0.8 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 EER25299.1 - 0.13 12.5 0.8 0.94 9.7 1.4 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family HIP1_clath_bdg PF16515.5 EER25299.1 - 0.3 11.7 2.9 0.76 10.4 0.8 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EER25299.1 - 1.4 9.0 4.5 7.9 6.5 2.8 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) WD40 PF00400.32 EER25300.1 - 2.2e-20 72.6 27.9 2.2e-08 34.6 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 EER25300.1 - 6.6e-18 65.0 0.1 1.3e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EER25300.1 - 0.00021 20.1 5.4 0.0067 15.1 0.7 3.1 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PHTB1_N PF14727.6 EER25300.1 - 0.11 11.8 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 PTHB1 N-terminus ANAPC4_WD40 PF12894.7 EER25300.1 - 0.15 12.4 0.3 4.9 7.5 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S13 PF00416.22 EER25301.1 - 4.4e-18 65.9 0.4 4.5e-16 59.4 0.4 2.3 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.21 EER25302.1 - 6.1e-50 169.6 0.2 7.3e-50 169.3 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CFEM PF05730.11 EER25303.1 - 6.1e-15 55.1 6.1 6.1e-15 55.1 6.1 1.5 2 0 0 2 2 2 1 CFEM domain Phage_holin_3_2 PF04550.12 EER25303.1 - 0.091 13.3 0.1 0.14 12.7 0.1 1.2 1 0 0 1 1 1 0 Phage holin family 2 Fungal_trans_2 PF11951.8 EER25304.1 - 3.1e-09 36.1 0.2 0.00063 18.7 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DEAD PF00270.29 EER25305.1 - 4.4e-48 163.4 0.0 2e-47 161.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER25305.1 - 1.4e-32 112.3 0.0 3.4e-32 111.1 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER25305.1 - 0.0092 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EER25305.1 - 0.11 11.8 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EER25305.1 - 0.21 10.7 0.0 0.33 10.1 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TauD PF02668.16 EER25307.1 - 1.1e-15 58.1 0.1 1.4e-15 57.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 EER25307.1 - 4.9e-06 25.9 0.0 6.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 CsiD Orn_Arg_deC_N PF02784.16 EER25308.1 - 1.8e-57 194.6 0.0 2.5e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EER25308.1 - 9.9e-13 48.2 0.0 1.2e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain INSIG PF07281.12 EER25312.1 - 1.2e-78 263.7 1.0 1.5e-78 263.3 1.0 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AICARFT_IMPCHas PF01808.18 EER25313.1 - 1.5e-90 303.6 0.0 3.1e-90 302.6 0.0 1.5 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EER25313.1 - 2.8e-26 91.5 0.1 5.4e-26 90.6 0.1 1.5 1 0 0 1 1 1 1 MGS-like domain Dis3l2_C_term PF17877.1 EER25313.1 - 0.097 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal Clathrin PF00637.20 EER25314.1 - 3.4e-198 649.5 36.3 8.3e-35 119.7 0.9 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EER25314.1 - 3.2e-31 106.1 1.6 0.0002 21.5 0.0 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EER25314.1 - 2.9e-30 104.0 1.0 1.5e-29 101.7 0.3 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 EER25314.1 - 0.0011 18.2 0.6 0.0027 17.0 0.6 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker TPR_7 PF13176.6 EER25314.1 - 0.0013 18.6 3.4 64 3.9 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 EER25314.1 - 0.013 16.3 10.8 0.32 11.9 0.2 7.1 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 EER25314.1 - 0.024 14.8 5.8 2.9 8.3 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EER25314.1 - 0.03 13.4 5.1 0.33 10.0 0.3 3.6 4 0 0 4 4 4 0 Coatomer WD associated region VapB_antitoxin PF09957.9 EER25314.1 - 0.044 13.7 0.3 0.19 11.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial antitoxin of type II TA system, VapB Vps39_1 PF10366.9 EER25314.1 - 0.28 11.5 5.0 59 4.0 0.0 5.5 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 CPSase_L_D2 PF02786.17 EER25315.1 - 1.2e-79 266.7 0.0 1.9e-79 266.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EER25315.1 - 1.9e-69 233.4 0.0 3.2e-69 232.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EER25315.1 - 7.2e-39 132.7 0.0 1.4e-38 131.8 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EER25315.1 - 2.6e-31 107.9 0.0 5.5e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EER25315.1 - 3.9e-27 95.5 0.0 1.1e-26 94.0 0.0 1.7 1 1 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EER25315.1 - 3.4e-18 65.2 2.3 8e-18 64.0 1.9 1.9 2 0 0 2 2 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EER25315.1 - 3.5e-09 36.4 2.7 3.8e-06 26.6 0.1 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EER25315.1 - 3.1e-08 33.4 0.0 6e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EER25315.1 - 5.8e-06 26.0 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EER25315.1 - 0.00021 21.4 0.0 0.0006 19.9 0.0 1.8 2 0 0 2 2 1 1 ATP-grasp domain RimK PF08443.11 EER25315.1 - 0.00075 19.1 0.0 0.0017 18.0 0.0 1.6 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 EER25315.1 - 0.0012 18.2 0.1 0.089 12.0 0.0 2.4 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EER25315.1 - 0.037 14.7 0.0 15 6.3 0.0 3.1 2 0 0 2 2 2 0 HlyD family secretion protein GARS_A PF01071.19 EER25315.1 - 0.051 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PYNP_C PF07831.13 EER25315.1 - 0.1 12.3 1.3 13 5.5 0.0 2.8 3 0 0 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain ATPgrasp_ST PF14397.6 EER25315.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp DUF4274 PF14096.6 EER25316.1 - 4e-05 23.5 2.1 88 3.2 0.0 7.0 5 1 1 6 6 6 0 Domain of unknown function (DUF4274) AAA_16 PF13191.6 EER25316.1 - 9.7e-05 22.8 0.0 0.00066 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EER25316.1 - 0.002 18.4 0.2 0.016 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_assoc_C PF09821.9 EER25316.1 - 0.0029 18.1 21.8 3.2 8.3 0.4 6.2 2 1 2 5 5 5 2 C-terminal AAA-associated domain T2SSS_2 PF16549.5 EER25316.1 - 0.015 15.3 15.1 10 6.2 0.2 6.5 2 1 6 9 9 9 0 Type II secretion system (T2SS) pilotin, S protein CG-1 PF03859.16 EER25316.1 - 0.017 14.9 18.5 12 5.7 0.1 8.7 5 3 6 11 11 11 0 CG-1 domain WVELL PF14043.6 EER25316.1 - 0.03 14.2 5.9 73 3.3 0.0 6.6 8 0 0 8 8 8 0 WVELL protein MRG PF05712.13 EER25316.1 - 0.054 12.8 0.7 3.8 6.8 0.2 2.5 1 1 1 2 2 2 0 MRG Fibrinogen_BP PF08017.11 EER25316.1 - 0.07 11.6 1.2 0.14 10.6 1.2 1.4 1 0 0 1 1 1 0 Fibrinogen binding protein Imm64 PF15600.6 EER25316.1 - 0.22 11.2 8.6 1.1 8.9 0.5 3.6 1 1 1 3 3 3 0 Immunity protein 64 Spo0A_C PF08769.11 EER25316.1 - 4.9 7.3 7.6 46 4.2 0.1 4.8 4 2 1 5 5 5 0 Sporulation initiation factor Spo0A C terminal DUF2207 PF09972.9 EER25317.1 - 0.25 10.1 1.6 0.33 9.7 1.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SdpI PF13630.6 EER25317.1 - 3.1 8.0 6.6 2 8.6 3.7 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family AAA_16 PF13191.6 EER25318.1 - 9.2e-07 29.4 0.0 2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EER25318.1 - 0.009 15.2 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ICAT PF06384.11 EER25319.1 - 0.17 12.1 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT GMP_synt_C PF00958.22 EER25320.1 - 2.1e-38 130.3 0.0 3.9e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EER25320.1 - 4.5e-31 108.1 0.0 8e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EER25320.1 - 8.9e-09 34.8 0.0 2.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EER25320.1 - 8.9e-07 28.9 0.0 2.1e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EER25320.1 - 0.00026 19.9 0.1 0.0015 17.4 0.1 1.9 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 EER25320.1 - 0.005 16.4 0.0 0.12 11.9 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 EER25320.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 EER25320.1 - 0.033 13.8 0.0 0.086 12.4 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 EER25320.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 EER25320.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 PP-loop family sCache_like PF16736.5 EER25320.1 - 0.19 11.8 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Single Cache-like Ribosomal_L5_C PF00673.21 EER25321.1 - 8.8e-23 80.3 0.0 1.3e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EER25321.1 - 2.1e-20 72.8 0.0 7.4e-20 71.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.22 EER25322.1 - 2.2e-19 68.9 0.2 2.7e-19 68.6 0.2 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.13 EER25323.1 - 5.1e-35 119.9 0.0 6.2e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Med6 PF04934.14 EER25323.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 MED6 mediator sub complex component Aa_trans PF01490.18 EER25324.1 - 3.8e-83 279.5 30.6 4.7e-83 279.2 30.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YpmT PF17431.2 EER25324.1 - 0.55 10.3 2.3 0.82 9.7 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized YmpT-like AA_permease PF00324.21 EER25325.1 - 3.3e-61 207.4 32.5 4.1e-61 207.0 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EER25325.1 - 5.2e-24 85.1 1.4 1.5e-08 34.1 0.1 3.5 4 0 0 4 4 4 3 Solute carrier family 12 HTH_23 PF13384.6 EER25326.1 - 4.3e-07 29.5 0.0 6.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EER25326.1 - 0.00064 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 EER25326.1 - 0.006 16.0 0.0 0.032 13.7 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 Sigma70_r4_2 PF08281.12 EER25326.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_7 PF02796.15 EER25326.1 - 0.029 14.5 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.7 EER25326.1 - 0.15 12.2 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain CDC45 PF02724.14 EER25327.1 - 0.00015 20.2 4.9 0.00019 19.9 4.9 1.1 1 0 0 1 1 1 1 CDC45-like protein zf-C2H2 PF00096.26 EER25327.1 - 0.046 14.2 0.8 0.046 14.2 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nop14 PF04147.12 EER25327.1 - 0.082 11.1 3.3 0.087 11.0 3.3 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 EER25327.1 - 0.19 11.4 6.9 0.24 11.1 6.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Transpos_assoc PF13963.6 EER25327.1 - 0.53 10.6 4.3 6.5 7.1 0.7 2.4 2 1 0 2 2 2 0 Transposase-associated domain DNA_pol_phi PF04931.13 EER25327.1 - 1.5 6.8 11.5 1.8 6.6 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sigma70_ner PF04546.13 EER25327.1 - 1.9 8.3 5.6 2.5 7.9 5.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.9 EER25327.1 - 5.5 6.0 14.1 7.5 5.6 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 EER25327.1 - 7.9 5.7 19.2 0.06 12.7 11.4 1.4 2 0 0 2 2 2 0 NOA36 protein SopE_GEF PF07487.13 EER25328.1 - 0.15 12.2 0.1 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 SopE GEF domain Peptidase_M35 PF02102.15 EER25329.1 - 7.3e-99 331.0 0.8 8.6e-99 330.8 0.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EER25329.1 - 5.4e-45 153.5 1.0 8.7e-45 152.8 1.0 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EER25329.1 - 0.0028 17.3 2.8 0.64 9.5 0.5 2.1 2 0 0 2 2 2 2 Putative peptidase family ssDNA-exonuc_C PF10141.9 EER25329.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain NB-ARC PF00931.22 EER25330.1 - 1.1e-05 24.7 0.0 1.3e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EER25330.1 - 0.00058 20.3 0.5 0.0026 18.2 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EER25330.1 - 0.04 14.2 0.1 0.082 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EER25330.1 - 0.04 13.6 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EER25330.1 - 0.066 13.1 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 EER25330.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PTR2 PF00854.21 EER25331.1 - 1.2e-06 27.7 0.2 3e-06 26.3 0.1 1.6 1 1 1 2 2 2 1 POT family Peptidase_M1 PF01433.20 EER25332.1 - 8e-44 149.8 0.1 1.2e-43 149.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EER25332.1 - 2.2e-36 124.4 0.2 7e-36 122.8 0.0 2.0 3 0 0 3 3 3 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EER25332.1 - 3.9e-28 98.9 0.0 6e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Ribosomal_L38e PF01781.18 EER25333.1 - 7.4e-32 109.3 3.0 8.5e-32 109.1 3.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family NTF2 PF02136.20 EER25334.1 - 2.4e-08 34.6 0.5 1.6e-07 31.9 0.5 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EER25334.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.5 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.11 EER25335.1 - 2.5e-95 319.5 0.3 2.3e-94 316.4 0.3 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EER25335.1 - 4.7e-20 71.4 4.1 2.9e-10 39.1 0.0 3.5 3 2 2 5 5 5 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EER25335.1 - 4.9e-11 42.5 0.0 8.5e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain GSG-1 PF07803.11 EER25335.1 - 0.1 12.5 0.2 0.93 9.4 0.1 2.2 2 0 0 2 2 2 0 GSG1-like protein PALP PF00291.25 EER25336.1 - 1.2e-47 162.8 1.2 1.4e-47 162.5 0.4 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.22 EER25337.1 - 1.5e-31 107.2 21.6 1.3e-07 31.1 0.9 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 EER25337.1 - 8 6.3 7.8 20 5.0 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) GHMP_kinases_N PF00288.26 EER25338.1 - 6.3e-16 58.4 0.1 1.3e-15 57.4 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EER25338.1 - 6.7e-08 32.8 0.0 1.6e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EER25338.1 - 0.00042 19.8 0.0 0.00087 18.8 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature zf-CCHC PF00098.23 EER25339.1 - 5e-06 26.3 2.0 7.6e-06 25.8 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EER25339.1 - 0.016 15.0 1.2 0.025 14.4 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle YabA PF06156.13 EER25339.1 - 0.21 12.3 0.9 0.95 10.1 0.7 2.2 2 0 0 2 2 2 0 Initiation control protein YabA APH PF01636.23 EER25340.1 - 1e-08 35.4 0.0 8.6e-08 32.4 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family CHAT PF12770.7 EER25341.1 - 1.8e-35 122.8 0.0 2.8e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 CHAT domain TPR_10 PF13374.6 EER25341.1 - 7.3e-33 111.5 21.9 4.6e-06 26.3 0.2 10.5 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_12 PF13424.6 EER25341.1 - 8.1e-11 42.1 14.1 0.57 10.5 0.0 9.5 7 3 3 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 EER25341.1 - 1.3e-05 25.7 4.4 13 6.6 0.0 7.0 6 2 1 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EER25341.1 - 5e-05 23.1 15.2 7.2 7.0 0.1 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EER25341.1 - 8.8e-05 22.6 0.3 16 6.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Urocanase_C PF17392.2 EER25341.1 - 0.0016 17.9 0.0 22 4.4 0.0 4.7 4 1 2 6 6 6 0 Urocanase C-terminal domain Coiled PF05710.12 EER25341.1 - 0.0063 17.3 0.4 62 4.5 0.0 4.5 1 1 3 4 4 4 0 Coiled coil TPR_8 PF13181.6 EER25341.1 - 0.037 14.3 2.7 3 8.3 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.12 EER25341.1 - 0.077 13.7 0.1 34 5.3 0.0 5.0 6 1 1 7 7 6 0 Sel1 repeat TPR_1 PF00515.28 EER25341.1 - 0.35 10.8 7.4 7.6 6.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3797 PF12677.7 EER25341.1 - 1.6 8.7 8.4 1.1e+02 2.8 0.1 5.2 6 0 0 6 6 6 0 Domain of unknown function (DUF3797) Histone PF00125.24 EER25343.1 - 3.2e-21 76.1 0.0 7.2e-21 74.9 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HNH_2 PF13391.6 EER25344.1 - 1.2e-18 67.0 1.1 5.9e-18 64.8 0.5 2.4 2 0 0 2 2 2 1 HNH endonuclease TraY PF05509.11 EER25344.1 - 0.13 12.4 0.3 0.29 11.2 0.3 1.5 1 0 0 1 1 1 0 TraY domain DDE_1 PF03184.19 EER25345.1 - 2.3e-47 160.9 3.6 2.5e-47 160.8 2.3 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 EER25345.1 - 6.3e-21 73.9 1.0 1.9e-20 72.3 1.0 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 EER25345.1 - 6.7e-17 61.3 3.1 1.2e-15 57.3 1.5 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain PhyH PF05721.13 EER25346.1 - 8.9e-28 98.0 0.0 1.3e-27 97.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.16 EER25347.1 - 4.1e-28 98.3 55.3 2.2e-27 95.9 53.9 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER25347.1 - 1.4e-16 60.1 24.7 1.9e-16 59.6 24.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER25347.1 - 2.8e-14 52.8 9.3 2.8e-14 52.8 9.3 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EER25347.1 - 0.76 8.0 12.1 0.088 11.1 3.9 2.9 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 EER25348.1 - 8.6e-07 28.6 0.0 1.4e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER25348.1 - 0.038 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF3435 PF11917.8 EER25349.1 - 5.2e-93 312.2 7.8 3e-78 263.6 3.1 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Pkinase PF00069.25 EER25350.1 - 2.2e-27 96.1 0.0 1.9e-26 93.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25350.1 - 9.9e-07 28.3 1.2 0.05 12.9 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER25350.1 - 0.061 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4050 PF13259.6 EER25353.1 - 1.6e-53 181.7 0.1 1.6e-53 181.7 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) zf-C3H1 PF10650.9 EER25353.1 - 0.14 11.9 0.7 0.25 11.1 0.7 1.3 1 0 0 1 1 1 0 Putative zinc-finger domain AAA PF00004.29 EER25354.1 - 1.1e-38 132.6 0.0 2e-37 128.6 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER25354.1 - 1.1e-07 31.5 0.1 2.8e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EER25354.1 - 6.3e-05 23.4 0.1 0.0019 18.6 0.1 2.9 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EER25354.1 - 0.00012 21.9 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EER25354.1 - 0.00035 20.9 0.1 0.029 14.6 0.1 2.9 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EER25354.1 - 0.00037 19.8 0.0 0.0007 18.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EER25354.1 - 0.00042 20.1 0.1 0.017 14.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EER25354.1 - 0.0005 20.3 0.0 0.004 17.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EER25354.1 - 0.0013 18.7 0.0 0.0039 17.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) WAPL PF07814.13 EER25354.1 - 0.0071 15.2 3.2 0.049 12.4 0.2 2.2 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin AAA_28 PF13521.6 EER25354.1 - 0.013 15.7 0.1 0.049 13.9 0.1 2.0 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EER25354.1 - 0.018 14.5 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EER25354.1 - 0.027 14.9 0.0 0.089 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EER25354.1 - 0.042 13.9 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EER25354.1 - 0.042 14.4 0.0 0.16 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EER25354.1 - 0.049 14.0 1.5 0.13 12.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EER25354.1 - 0.067 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EER25354.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Astro_capsid_p PF12226.8 EER25354.1 - 5.1 6.2 7.3 0.27 10.3 1.8 1.6 2 0 0 2 2 2 0 Turkey astrovirus capsid protein LIM_bind PF01803.16 EER25355.1 - 1e-62 211.9 0.0 1e-62 211.9 0.0 4.4 3 1 1 4 4 4 1 LIM-domain binding protein cobW PF02492.19 EER25356.1 - 3.7e-34 117.8 0.0 4.6e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EER25356.1 - 4.3e-07 29.2 0.1 8.3e-05 21.7 0.1 2.0 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EER25356.1 - 0.0058 16.7 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.12 EER25356.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EER25356.1 - 0.1 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea GTP_EFTU PF00009.27 EER25356.1 - 0.17 11.4 0.0 5 6.6 0.0 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 EER25356.1 - 0.25 11.8 0.0 0.35 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain BING4CT PF08149.11 EER25357.1 - 4.5e-40 135.3 0.0 5.3e-35 119.1 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EER25357.1 - 9.3e-11 41.9 0.0 1.1 9.7 0.0 5.8 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EER25357.1 - 5.8e-05 23.8 0.6 0.82 10.6 0.0 4.5 5 1 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EER25357.1 - 0.0028 16.8 0.0 0.48 9.4 0.0 2.6 3 0 0 3 3 3 2 Coatomer WD associated region RIBIOP_C PF04950.12 EER25358.1 - 1.3e-107 359.6 0.1 6e-107 357.4 0.0 2.0 3 0 0 3 3 3 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EER25358.1 - 3.3e-21 75.2 0.0 7.7e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain HlyIII PF03006.20 EER25359.1 - 1.4e-47 162.3 18.7 1.6e-47 162.1 18.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF726 PF05277.12 EER25360.1 - 6.7e-119 396.8 0.2 9.2e-119 396.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 EER25360.1 - 0.00063 19.9 1.3 0.00092 19.4 0.0 1.9 3 0 0 3 3 3 1 Thioesterase domain Abhydrolase_6 PF12697.7 EER25360.1 - 0.0028 18.3 3.8 0.0094 16.6 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER25360.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PE-PPE PF08237.11 EER25360.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain LCAT PF02450.15 EER25360.1 - 0.23 10.6 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Methyltransf_23 PF13489.6 EER25361.1 - 1e-21 77.5 0.0 1.5e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER25361.1 - 4.3e-12 46.6 0.0 1.3e-11 45.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER25361.1 - 4.4e-11 43.4 0.0 3.1e-10 40.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER25361.1 - 7.8e-08 32.3 0.0 1.1e-06 28.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER25361.1 - 7.8e-08 32.9 0.0 2.3e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER25361.1 - 0.00013 21.4 0.0 0.013 14.9 0.0 2.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EER25361.1 - 0.00063 19.3 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EER25361.1 - 0.0014 18.0 0.0 0.05 12.9 0.0 2.4 3 0 0 3 3 3 1 O-methyltransferase domain Methyltransf_4 PF02390.17 EER25361.1 - 0.0022 17.5 0.0 0.0068 15.9 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.9 EER25361.1 - 0.0027 17.5 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EER25361.1 - 0.0069 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EER25361.1 - 0.072 13.2 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.12 EER25361.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SNAP PF14938.6 EER25362.1 - 1.1e-115 385.9 18.9 1.3e-115 385.7 18.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EER25362.1 - 3.3e-08 33.7 10.4 0.0013 18.9 0.9 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER25362.1 - 9e-05 22.4 11.2 0.06 13.6 0.1 5.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EER25362.1 - 0.0001 22.7 11.5 3.6 8.4 0.2 6.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EER25362.1 - 0.00082 19.3 13.1 0.94 9.8 0.1 6.7 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EER25362.1 - 0.033 14.2 11.5 1.5 9.1 0.2 6.2 4 1 1 6 6 6 0 Tetratricopeptide repeat DFF40 PF09230.10 EER25362.1 - 0.056 13.0 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa DUF4207 PF13904.6 EER25362.1 - 0.12 12.1 0.7 0.16 11.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) TPR_10 PF13374.6 EER25362.1 - 0.13 12.1 5.8 3.3 7.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EER25362.1 - 0.38 10.8 9.1 4.5 7.4 0.2 4.6 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EER25362.1 - 0.49 10.3 15.4 1.2 9.1 0.4 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.12 EER25362.1 - 2.6 8.1 14.6 10 6.2 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EER25362.1 - 3.6 8.3 16.0 33 5.2 1.9 4.8 1 1 3 4 4 4 0 Tetratricopeptide repeat Ank PF00023.30 EER25363.1 - 8.6e-07 29.1 0.5 0.0012 19.2 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EER25363.1 - 7.6e-06 26.4 0.1 4.1e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER25363.1 - 4.3e-05 23.7 0.1 0.0002 21.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EER25363.1 - 0.0001 22.8 0.0 0.0011 19.4 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER25363.1 - 0.00099 19.4 2.3 0.13 12.9 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat MecA_N PF05223.11 EER25363.1 - 0.068 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 NTF2-like N-terminal transpeptidase domain RsgA_GTPase PF03193.16 EER25363.1 - 0.079 12.9 0.2 4.4 7.2 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase Torsin PF06309.11 EER25363.1 - 0.14 12.3 0.1 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 Torsin Pyr_redox_2 PF07992.14 EER25365.1 - 6.5e-07 28.9 0.0 3.2e-06 26.6 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER25365.1 - 0.021 15.1 0.0 0.069 13.4 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EER25365.1 - 0.077 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EER25365.1 - 0.16 11.0 0.7 1.7 7.6 0.1 2.4 2 1 1 3 3 3 0 FAD binding domain Reo_sigmaC_M PF17750.1 EER25366.1 - 0.044 13.6 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 Reovirus sigma C capsid protein triple beta spiral Sec62 PF03839.16 EER25367.1 - 1.5e-72 243.6 2.0 1.5e-72 243.6 2.0 2.2 2 0 0 2 2 2 1 Translocation protein Sec62 Zip PF02535.22 EER25367.1 - 0.081 12.1 13.0 0.029 13.6 4.5 2.3 2 1 0 2 2 2 0 ZIP Zinc transporter HTH_18 PF12833.7 EER25367.1 - 0.11 12.7 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4834 PF16118.5 EER25367.1 - 3.5 8.6 8.0 52 4.9 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Mcm10 PF09332.11 EER25368.1 - 3.5 7.0 11.2 7.4 5.9 10.1 2.0 1 1 1 2 2 2 0 Mcm10 replication factor Abhydrolase_6 PF12697.7 EER25369.1 - 2.1e-15 57.9 0.0 2.8e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER25369.1 - 3.5e-11 43.2 0.0 2.3e-10 40.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER25369.1 - 1.2e-07 31.3 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EER25369.1 - 0.038 13.9 0.5 0.72 9.7 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.14 EER25369.1 - 0.19 10.4 0.0 16 4.1 0.0 2.5 3 0 0 3 3 3 0 Ndr family PriC PF07445.12 EER25370.1 - 0.0002 21.4 1.3 0.00038 20.4 1.3 1.5 1 0 0 1 1 1 1 Primosomal replication protein priC Shugoshin_N PF07558.11 EER25370.1 - 0.0032 17.3 0.7 0.0087 15.9 0.7 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DivIC PF04977.15 EER25370.1 - 0.09 12.6 0.0 0.09 12.6 0.0 2.5 2 1 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 EER25370.1 - 0.45 11.2 0.2 0.45 11.2 0.2 3.2 3 0 0 3 3 3 0 SlyX Neur_chan_memb PF02932.16 EER25370.1 - 0.83 9.7 7.1 0.14 12.2 2.7 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region YajC PF02699.15 EER25370.1 - 0.97 9.4 3.4 1.6 8.7 3.4 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit DUF2968 PF11180.8 EER25370.1 - 3.5 7.2 14.5 1.2 8.8 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Carn_acyltransf PF00755.20 EER25371.1 - 1e-207 691.4 0.0 1.2e-207 691.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Glyco_transf_90 PF05686.12 EER25372.1 - 6.8e-31 107.6 0.1 9.3e-31 107.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EER25372.1 - 0.02 15.3 0.1 0.048 14.0 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Rxt3 PF08642.10 EER25373.1 - 1.2e-44 152.1 0.3 3.6e-44 150.6 0.0 2.0 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EER25373.1 - 0.0013 18.8 0.0 0.0044 17.1 0.0 1.8 2 0 0 2 2 2 1 LCCL domain CLN3 PF02487.17 EER25374.1 - 4.2e-162 539.7 0.5 4.9e-162 539.5 0.5 1.0 1 0 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.13 EER25375.1 - 1.8e-35 122.8 0.0 6.2e-25 88.3 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EER25375.1 - 0.0027 16.6 0.0 0.0044 15.9 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Aminotran_3 PF00202.21 EER25376.1 - 4.1e-111 371.5 0.0 5e-111 371.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EER25376.1 - 0.00016 20.9 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Retrotran_gag_2 PF14223.6 EER25377.1 - 0.001 18.7 0.7 0.0024 17.5 0.0 1.9 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Ribosomal_60s PF00428.19 EER25377.1 - 0.049 14.2 1.1 0.12 13.0 1.1 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4927 PF16279.5 EER25377.1 - 0.14 13.2 3.5 0.41 11.7 3.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4927) YebO PF13974.6 EER25377.1 - 1.7 8.7 7.3 5.9 7.0 6.7 2.2 2 0 0 2 2 2 0 YebO-like protein Peptidase_S46 PF10459.9 EER25377.1 - 2.2 6.8 9.2 2.8 6.5 9.2 1.1 1 0 0 1 1 1 0 Peptidase S46 HMGL-like PF00682.19 EER25378.1 - 4.2e-45 154.4 0.0 2.6e-34 119.0 0.2 2.0 2 0 0 2 2 2 2 HMGL-like Dsh_C PF12316.8 EER25378.1 - 0.0031 17.9 3.3 0.0046 17.4 3.3 1.2 1 0 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal Diphthamide_syn PF01866.17 EER25379.1 - 2e-116 388.7 0.0 2.7e-116 388.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.25 EER25380.1 - 9.1e-07 28.9 0.1 1e-05 25.5 0.1 2.2 1 1 0 1 1 1 1 Bromodomain ATG16 PF08614.11 EER25381.1 - 0.0058 16.9 2.9 0.0058 16.9 2.9 1.5 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) SEO_N PF14576.6 EER25381.1 - 0.014 14.6 0.4 0.017 14.3 0.4 1.1 1 0 0 1 1 1 0 Sieve element occlusion N-terminus Uds1 PF15456.6 EER25381.1 - 0.089 13.0 5.3 0.12 12.6 5.3 1.1 1 0 0 1 1 1 0 Up-regulated During Septation Allexi_40kDa PF05549.11 EER25381.1 - 0.1 12.1 4.8 0.15 11.6 3.2 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein CSRNP_N PF16019.5 EER25381.1 - 0.19 11.7 2.4 0.26 11.2 2.4 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus FAM76 PF16046.5 EER25381.1 - 0.27 10.5 5.4 0.25 10.7 4.6 1.4 1 1 0 1 1 1 0 FAM76 protein OSCP PF00213.18 EER25382.1 - 6.8e-44 150.0 4.5 8.4e-44 149.7 4.5 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF1539 PF07560.11 EER25382.1 - 0.0069 16.5 0.6 1.4 9.1 0.0 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1539) Mob1_phocein PF03637.17 EER25383.1 - 2.1e-73 245.9 0.0 2.7e-73 245.5 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.10 EER25384.1 - 1.3e-134 449.5 0.0 1.8e-134 449.1 0.0 1.2 1 0 0 1 1 1 1 Rgp1 Spo0M PF07070.11 EER25384.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 SpoOM protein Arrestin_N PF00339.29 EER25384.1 - 0.045 13.8 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Neugrin PF06413.11 EER25385.1 - 7e-13 49.1 2.2 9.7e-13 48.6 0.5 1.8 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.7 EER25385.1 - 1.2e-06 28.8 11.4 4.4e-06 27.0 11.5 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Sigma70_r3 PF04539.16 EER25385.1 - 0.081 13.0 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Sigma-70 region 3 FeoC PF09012.10 EER25385.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator WD40 PF00400.32 EER25386.1 - 3.5e-18 65.6 7.2 0.0062 17.4 0.0 8.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25386.1 - 0.00045 20.5 0.1 21 5.5 0.0 5.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SPO22 PF08631.10 EER25387.1 - 1.3e-49 169.1 14.9 3.6e-29 102.1 1.3 4.2 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like FAT PF02259.23 EER25387.1 - 0.0015 17.8 0.3 0.0015 17.8 0.3 1.8 2 0 0 2 2 2 1 FAT domain TPR_2 PF07719.17 EER25387.1 - 0.14 12.3 3.1 2.4 8.5 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER25387.1 - 0.24 11.7 8.2 6.1 7.2 0.1 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn_clus PF00172.18 EER25388.1 - 8.2e-06 25.8 9.9 1.5e-05 25.0 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-Q PF13094.6 EER25389.1 - 2.5e-44 151.4 5.9 4e-44 150.8 5.9 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit Ran-binding PF05508.11 EER25389.1 - 0.2 10.6 2.8 0.44 9.5 0.7 2.1 2 0 0 2 2 2 0 RanGTP-binding protein DUF2203 PF09969.9 EER25389.1 - 0.31 11.8 4.5 0.3 11.8 0.3 2.6 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4407 PF14362.6 EER25389.1 - 0.36 10.1 4.3 0.15 11.4 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) COG2 PF06148.11 EER25389.1 - 0.48 10.5 5.2 1.6 8.8 2.8 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HLH PF00010.26 EER25390.1 - 9.7e-08 31.9 0.0 2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HD PF01966.22 EER25392.1 - 0.0024 18.1 0.2 0.0042 17.3 0.2 1.4 1 0 0 1 1 1 1 HD domain CtaG_Cox11 PF04442.14 EER25393.1 - 5.7e-62 208.2 0.1 8.1e-62 207.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 DNA_pol3_delta2 PF13177.6 EER25394.1 - 1.7e-10 40.9 0.1 3.8e-10 39.8 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EER25394.1 - 2.2e-06 28.1 0.1 4.6e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EER25394.1 - 1.5e-05 25.3 0.1 6.3e-05 23.3 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EER25394.1 - 0.00044 20.7 1.1 0.0028 18.1 0.6 2.4 2 1 0 2 2 2 1 AAA ATPase domain Rep_fac_C PF08542.11 EER25394.1 - 0.0033 17.8 0.2 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_24 PF13479.6 EER25394.1 - 0.004 16.9 0.4 0.01 15.6 0.4 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EER25394.1 - 0.017 15.1 0.0 0.079 12.9 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain T4SS-DNA_transf PF02534.14 EER25394.1 - 0.059 12.2 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ABC_tran PF00005.27 EER25394.1 - 0.088 13.3 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Ribosomal_L16 PF00252.18 EER25395.1 - 2.4e-35 121.4 0.2 3.7e-35 120.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 EER25396.1 - 2.6e-59 199.9 0.1 6.6e-59 198.6 0.0 1.8 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EER25396.1 - 9.7e-14 51.5 0.0 3e-13 49.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EER25396.1 - 6.9e-10 39.5 0.2 2.7e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EER25396.1 - 4.3e-05 23.8 0.0 0.00013 22.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EER25396.1 - 0.0003 20.7 0.0 0.00076 19.4 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EER25396.1 - 0.00082 19.8 0.0 0.0046 17.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EER25396.1 - 0.0016 18.6 0.0 0.0059 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EER25396.1 - 0.0046 16.7 0.0 0.0096 15.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EER25396.1 - 0.0063 16.3 0.0 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EER25396.1 - 0.012 15.6 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EER25396.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EER25396.1 - 0.055 13.5 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EER25396.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.15 EER25396.1 - 0.12 12.2 0.1 0.42 10.5 0.1 1.9 1 1 1 2 2 2 0 NTPase AAA_28 PF13521.6 EER25396.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EER25396.1 - 0.14 12.1 0.0 0.82 9.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain NAD_binding_8 PF13450.6 EER25397.1 - 4.6e-16 58.8 0.0 1.3e-15 57.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EER25397.1 - 1.4e-13 51.0 0.0 3.8e-08 33.1 0.0 3.1 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase DAO PF01266.24 EER25397.1 - 2.5e-06 27.3 0.1 0.0069 16.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER25397.1 - 0.0055 16.0 0.0 0.015 14.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 EER25397.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Septin PF00735.18 EER25398.1 - 3.2e-121 403.9 0.2 3.2e-121 403.9 0.2 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EER25398.1 - 1.2e-08 35.0 0.4 3.9e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER25398.1 - 1.6e-06 27.8 1.1 0.00067 19.2 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EER25398.1 - 9.4e-05 22.9 3.0 0.016 15.7 0.0 2.7 2 1 1 3 3 3 1 ABC transporter Roc PF08477.13 EER25398.1 - 0.0011 19.2 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EER25398.1 - 0.0015 19.0 0.1 0.0046 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 EER25398.1 - 0.0022 17.3 3.1 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EER25398.1 - 0.0027 17.6 1.0 0.0027 17.6 1.0 3.4 3 1 0 3 3 2 1 RsgA GTPase AAA_22 PF13401.6 EER25398.1 - 0.0032 17.8 1.2 0.012 15.9 0.0 2.5 2 2 0 2 2 2 1 AAA domain Ras PF00071.22 EER25398.1 - 0.0058 16.2 0.0 0.026 14.1 0.0 2.1 1 0 0 1 1 1 1 Ras family AAA_29 PF13555.6 EER25398.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EER25398.1 - 0.04 13.6 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EER25398.1 - 0.045 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EER25398.1 - 0.057 13.9 5.3 10 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EER25398.1 - 0.073 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.17 EER25398.1 - 0.077 12.8 3.4 2.3 7.9 0.1 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EER25398.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EER25398.1 - 0.093 13.1 0.6 0.52 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.15 EER25398.1 - 0.16 11.5 6.7 0.24 10.9 6.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.23 EER25398.1 - 0.18 11.8 8.8 0.78 9.8 0.0 3.5 3 1 0 3 3 2 0 Dynamin family DUF87 PF01935.17 EER25398.1 - 0.75 9.9 4.3 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain DUF3987 PF13148.6 EER25398.1 - 1.6 7.7 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF2937 PF11157.8 EER25398.1 - 1.7 8.3 3.4 3.1 7.5 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Atg14 PF10186.9 EER25398.1 - 2 7.4 9.5 3 6.8 9.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Strep_SA_rep PF06696.11 EER25398.1 - 4.6 7.4 6.5 2.7 8.1 3.8 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat UPF0121 PF03661.13 EER25399.1 - 6.5e-30 104.3 4.5 8.6e-30 103.9 4.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) UPF0060 PF02694.15 EER25399.1 - 0.035 14.3 0.8 0.035 14.3 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Mito_carr PF00153.27 EER25400.1 - 1.1e-64 214.4 1.5 5.5e-20 71.1 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein CHCH PF06747.13 EER25402.1 - 4.1e-08 33.1 2.6 7.4e-08 32.3 2.6 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EER25402.1 - 0.081 13.4 1.4 0.18 12.3 1.4 1.7 1 0 0 1 1 1 0 GCK domain UreF PF01730.16 EER25402.1 - 1.2 9.7 4.9 0.32 11.6 0.5 2.1 2 0 0 2 2 2 0 UreF DUF3128 PF11326.8 EER25402.1 - 1.7 9.1 4.7 0.45 10.9 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) DUF4495 PF14906.6 EER25403.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) TPK_catalytic PF04263.16 EER25404.1 - 9e-32 109.6 0.0 1.4e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EER25404.1 - 4.5e-19 67.9 0.1 7.1e-19 67.3 0.1 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain MIF4G PF02854.19 EER25405.1 - 1.5e-57 194.6 0.0 9.1e-31 107.1 0.0 3.7 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 EER25405.1 - 1.4e-41 142.4 12.3 1.4e-41 142.4 12.3 4.0 4 0 0 4 4 4 1 Up-frameshift suppressor 2 FMO-like PF00743.19 EER25406.1 - 1.5e-22 79.8 0.1 9.8e-21 73.8 0.1 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EER25406.1 - 5.9e-15 55.3 0.1 2.7e-14 53.1 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER25406.1 - 3.8e-11 43.1 0.0 3.6e-10 39.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EER25406.1 - 8.5e-11 41.6 0.0 2.9e-09 36.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER25406.1 - 4.7e-09 35.9 0.2 7.6e-07 28.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EER25406.1 - 2.1e-06 27.6 0.0 8.1e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EER25406.1 - 1.2e-05 25.4 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EER25406.1 - 6.4e-05 22.3 0.1 0.00014 21.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EER25406.1 - 0.00048 20.1 0.0 0.004 17.2 0.0 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EER25406.1 - 0.0034 16.5 0.3 0.0051 15.9 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain AbiJ_NTD5 PF18865.1 EER25406.1 - 0.025 14.4 0.2 4.9 7.0 0.0 2.5 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 Pyr_redox PF00070.27 EER25406.1 - 0.034 14.7 0.1 6.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RVT_thumb PF06817.14 EER25406.1 - 0.14 12.0 0.4 0.94 9.4 0.5 2.2 2 0 0 2 2 2 0 Reverse transcriptase thumb domain 2-Hacid_dh_C PF02826.19 EER25406.1 - 0.18 11.2 0.1 0.61 9.4 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EER25406.1 - 0.2 10.9 0.3 0.75 9.0 0.4 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EER25406.1 - 0.25 10.0 0.8 0.46 9.1 0.8 1.4 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_18 PF00704.28 EER25407.1 - 1.3e-86 291.2 0.6 1.6e-86 290.9 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 EER25407.1 - 2.2e-13 50.0 0.1 4.4e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 LysM domain Glyco_transf_8 PF01501.20 EER25409.1 - 0.00017 21.3 0.2 0.00023 20.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 SUN PF03856.13 EER25410.1 - 3.4e-95 318.2 9.1 4.3e-95 317.8 9.1 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF1768 PF08719.11 EER25411.1 - 1.8e-55 187.6 0.0 2.1e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Ribosomal_L1 PF00687.21 EER25412.1 - 2.1e-61 207.2 4.5 3.8e-61 206.4 4.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family ETF PF01012.21 EER25413.1 - 2.8e-46 157.7 6.0 5.2e-46 156.8 6.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EER25413.1 - 1.5e-33 114.6 0.1 3.7e-33 113.4 0.1 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain AAA PF00004.29 EER25414.1 - 3.1e-11 43.8 0.0 6.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EER25414.1 - 3.9e-07 30.4 0.0 9.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EER25414.1 - 2.9e-05 24.1 0.0 6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EER25414.1 - 0.00013 21.9 0.1 0.00054 19.9 0.1 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EER25414.1 - 0.00015 21.5 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EER25414.1 - 0.0028 18.1 0.0 0.018 15.4 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EER25414.1 - 0.0034 17.6 0.0 0.0098 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EER25414.1 - 0.0042 16.8 0.4 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EER25414.1 - 0.0067 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EER25414.1 - 0.018 14.9 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 EER25414.1 - 0.058 13.3 0.1 0.15 11.9 0.1 1.7 1 1 0 1 1 1 0 NTPase T2SSE PF00437.20 EER25414.1 - 0.11 11.5 0.1 0.56 9.2 0.1 1.9 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EER25414.1 - 0.15 12.3 0.1 0.63 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EER25414.1 - 0.16 11.3 0.0 1.1 8.6 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI SWIRM PF04433.17 EER25415.1 - 1e-30 105.9 0.1 2.3e-30 104.7 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EER25415.1 - 1.6e-28 98.4 8.6 1.6e-28 98.4 8.6 1.8 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EER25415.1 - 6e-08 32.8 0.2 1.1e-07 31.9 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER25415.1 - 1.3e-05 25.3 0.3 3.3e-05 24.0 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EER25415.1 - 0.058 13.2 4.0 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type Trypan_PARP PF05887.11 EER25416.1 - 0.0062 16.5 2.1 0.0062 16.5 2.1 2.5 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) ResIII PF04851.15 EER25417.1 - 3.4e-25 89.0 0.0 5.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EER25417.1 - 2.9e-15 56.5 0.1 3.2e-13 50.0 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EER25417.1 - 1.2e-10 41.4 0.0 2.7e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EER25417.1 - 6.4e-05 22.7 0.0 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EER25417.1 - 0.0012 18.2 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SwrA PF17423.2 EER25417.1 - 0.03 14.3 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 Swarming motility protein PGAP1 PF07819.13 EER25418.1 - 6.1e-87 291.2 0.0 1e-86 290.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EER25418.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 EER25418.1 - 0.00059 20.5 0.1 0.001 19.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER25418.1 - 0.0014 18.3 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.14 EER25418.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EER25418.1 - 0.01 15.2 0.0 0.018 14.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LCAT PF02450.15 EER25418.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.11 EER25418.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) COesterase PF00135.28 EER25418.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Esterase PF00756.20 EER25418.1 - 0.17 11.5 0.1 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 Putative esterase NAD_binding_10 PF13460.6 EER25419.1 - 1.7e-08 34.6 0.0 7e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EER25419.1 - 0.0061 16.1 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family MFS_1 PF07690.16 EER25420.1 - 7.9e-20 71.1 14.0 2e-10 40.2 4.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 EER25421.1 - 1.1e-37 129.4 0.5 6e-36 123.7 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER25421.1 - 2e-29 102.8 1.6 2.6e-15 56.6 0.2 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER25421.1 - 3.1e-05 24.0 1.3 0.0021 18.0 1.3 2.2 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EER25421.1 - 0.0018 18.3 1.7 0.55 10.2 1.7 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EER25421.1 - 0.0093 15.5 0.1 0.05 13.1 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EER25421.1 - 0.059 13.3 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 EER25421.1 - 0.14 12.0 0.5 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase APG17 PF04108.12 EER25422.1 - 4.5e-132 440.9 1.5 5.3e-132 440.7 1.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 FliE PF02049.18 EER25422.1 - 0.041 14.0 0.6 0.39 10.9 0.2 2.6 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE ApoLp-III PF07464.11 EER25422.1 - 0.061 13.4 4.4 27 4.8 0.2 3.4 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) RasGAP_C PF03836.15 EER25422.1 - 0.16 12.1 4.0 13 6.0 0.1 3.6 4 0 0 4 4 4 0 RasGAP C-terminus DUF2408 PF10303.9 EER25422.1 - 0.24 12.0 4.4 0.72 10.4 2.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) Prominin PF05478.11 EER25422.1 - 0.27 9.1 2.6 2.6 5.9 0.1 2.1 2 0 0 2 2 2 0 Prominin T3SS_needle_F PF09392.10 EER25422.1 - 0.87 9.8 3.6 1.8 8.8 1.9 2.4 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Snapin_Pallidin PF14712.6 EER25422.1 - 7.6 7.0 10.1 7.6 7.0 0.6 4.4 5 0 0 5 5 5 0 Snapin/Pallidin WD40 PF00400.32 EER25423.1 - 5e-44 147.4 23.3 5.2e-08 33.4 0.6 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EER25423.1 - 1.6e-13 50.3 1.3 3.2e-13 49.3 1.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER25423.1 - 2.4e-10 40.0 2.1 4e-10 39.3 1.1 2.0 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.8 EER25423.1 - 4.3e-10 38.9 5.2 0.082 11.5 0.2 5.1 4 1 0 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EER25423.1 - 1.7e-06 28.2 0.0 0.058 13.7 0.0 4.7 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EER25423.1 - 0.00023 21.0 0.1 0.00087 19.2 0.0 2.0 2 0 0 2 2 2 1 F-box Retrotrans_gag PF03732.17 EER25423.1 - 0.12 12.7 0.1 0.39 11.0 0.1 1.8 1 0 0 1 1 1 0 Retrotransposon gag protein RIO1 PF01163.22 EER25426.1 - 8e-74 247.3 0.1 8e-74 247.3 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EER25426.1 - 0.0021 18.0 0.1 0.32 10.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EER25426.1 - 0.036 13.4 0.2 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.19 EER25427.1 - 2.3e-66 223.4 22.0 8.4e-66 221.6 22.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EER25427.1 - 2.2e-31 108.6 0.1 1.4e-30 106.0 0.0 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EER25427.1 - 6.6e-18 65.6 12.2 3.4e-11 43.5 3.3 3.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EER25427.1 - 3.9e-14 53.2 52.1 3.2e-10 40.3 13.1 4.3 2 2 1 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 EER25427.1 - 2.4e-06 28.2 48.4 2.4e-06 28.2 48.4 7.0 2 2 1 3 3 2 1 AAA domain AAA_29 PF13555.6 EER25427.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain COG5 PF10392.9 EER25427.1 - 0.0056 16.9 5.1 0.0056 16.9 5.1 6.2 5 2 2 7 7 7 1 Golgi transport complex subunit 5 APG6_N PF17675.1 EER25427.1 - 0.0087 16.6 15.6 0.0087 16.6 15.6 8.9 4 2 4 8 8 8 3 Apg6 coiled-coil region VWA_3 PF13768.6 EER25427.1 - 0.087 12.8 2.9 0.84 9.6 1.8 3.1 2 1 0 2 2 2 0 von Willebrand factor type A domain ABC_tran PF00005.27 EER25427.1 - 0.46 11.0 0.0 0.46 11.0 0.0 5.9 3 2 0 3 3 1 0 ABC transporter DEAD PF00270.29 EER25427.1 - 0.7 9.6 3.6 19 4.9 0.0 3.8 4 0 0 4 4 4 0 DEAD/DEAH box helicase DUF1154 PF06631.11 EER25427.1 - 1.2 9.2 8.7 0.96 9.5 4.7 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1154) Mce4_CUP1 PF11887.8 EER25427.1 - 1.4 8.3 9.7 7.5 5.9 0.3 4.5 4 1 0 4 4 4 0 Cholesterol uptake porter CUP1 of Mce4, putative YvrJ PF12841.7 EER25427.1 - 1.9 8.1 9.4 15 5.2 1.3 4.5 4 0 0 4 4 4 0 YvrJ protein family DUF87 PF01935.17 EER25427.1 - 2.8 8.0 0.0 2.8 8.0 0.0 6.7 3 2 3 6 6 5 0 Helicase HerA, central domain GAS PF13851.6 EER25427.1 - 3.9 6.8 106.2 0.031 13.6 16.6 7.4 4 2 2 7 7 7 0 Growth-arrest specific micro-tubule binding DUF3605 PF12239.8 EER25428.1 - 9.6e-59 198.1 0.1 1.1e-58 197.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Endonuc-HincII PF09226.11 EER25428.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease HincII FAD_binding_6 PF00970.24 EER25429.1 - 6.2e-32 109.9 0.0 1.1e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EER25429.1 - 1.3e-27 96.6 0.0 2.1e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EER25429.1 - 1.3e-06 28.6 0.0 0.0006 20.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EER25429.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain tRNA-synt_1d PF00750.19 EER25430.1 - 4.1e-99 331.8 7.7 1.8e-98 329.8 7.7 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EER25430.1 - 4.9e-28 97.7 0.0 1.2e-27 96.5 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EER25430.1 - 9.6e-06 26.1 0.0 2.7e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Presenilin PF01080.17 EER25431.1 - 0.48 9.1 1.5 1 8.1 1.5 1.5 1 0 0 1 1 1 0 Presenilin Jnk-SapK_ap_N PF09744.9 EER25433.1 - 1.3 9.3 14.4 0.18 12.1 2.0 2.8 2 2 1 3 3 3 0 JNK_SAPK-associated protein-1 GrpE PF01025.19 EER25433.1 - 1.4 8.6 4.7 0.61 9.7 0.5 2.1 2 0 0 2 2 2 0 GrpE NAM-associated PF14303.6 EER25434.1 - 0.093 13.4 6.4 0.16 12.7 6.4 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pkinase PF00069.25 EER25435.1 - 8.2e-25 87.7 0.0 1.5e-24 86.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25435.1 - 1.2e-08 34.6 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER25435.1 - 0.028 13.2 0.0 0.034 12.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EER25435.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.29 EER25436.1 - 5.1e-41 140.4 1.0 9.3e-41 139.5 1.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER25436.1 - 6.4e-32 110.2 0.1 2.1e-29 102.1 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EER25436.1 - 6.9e-07 29.4 0.0 1.7e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EER25436.1 - 0.66 9.4 2.7 2 7.8 0.1 2.4 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AA_permease PF00324.21 EER25438.1 - 1.7e-118 396.3 38.3 2.9e-118 395.5 38.3 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER25438.1 - 4.2e-31 108.2 36.2 4.2e-31 108.2 36.2 1.8 1 1 1 2 2 2 1 Amino acid permease Acyltransferase PF01553.21 EER25439.1 - 2.9e-14 52.8 0.0 5.6e-14 51.9 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.9 EER25440.1 - 5.1e-46 155.3 1.6 5.7e-46 155.1 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Annexin PF00191.20 EER25443.1 - 3.5e-64 212.8 7.3 1.3e-18 66.8 0.4 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.6 EER25443.1 - 0.012 16.1 0.3 4.2 7.9 0.0 3.4 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF3574 PF12098.8 EER25443.1 - 0.18 11.6 0.1 19 5.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) EBP PF05241.12 EER25444.1 - 1.8e-62 209.9 10.9 2.2e-62 209.6 10.9 1.1 1 0 0 1 1 1 1 Emopamil binding protein SfLAP PF11139.8 EER25444.1 - 8 5.8 11.4 0.093 12.2 0.8 2.6 2 1 0 2 2 2 0 Sap, sulfolipid-1-addressing protein zf-C3HC4 PF00097.25 EER25445.1 - 1.2e-07 31.5 4.3 1.2e-07 31.5 4.3 5.0 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER25445.1 - 1.5e-07 31.3 5.3 1.5e-07 31.3 5.3 3.8 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EER25445.1 - 3.7e-07 29.9 3.1 3.7e-07 29.9 3.1 4.8 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EER25445.1 - 1.5e-06 27.9 0.5 1.5e-06 27.9 0.5 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.6 EER25445.1 - 1.2e-05 25.5 6.6 1.2e-05 25.5 6.6 4.3 4 0 0 4 4 4 1 Ring finger domain SH3_9 PF14604.6 EER25445.1 - 6.4e-05 22.7 0.3 6.4e-05 22.7 0.3 2.5 3 0 0 3 3 3 1 Variant SH3 domain zf-C3HC4_4 PF15227.6 EER25445.1 - 0.00022 21.3 6.5 0.00022 21.3 6.5 4.3 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.28 EER25445.1 - 0.0053 16.3 0.2 0.0053 16.3 0.2 2.2 2 0 0 2 2 2 1 SH3 domain CBM_21 PF03370.13 EER25447.1 - 5.2e-34 116.8 0.8 9.4e-34 116.0 0.8 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EER25447.1 - 1.1e-08 35.5 1.6 2.3e-08 34.5 1.6 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) CENP-T_C PF15511.6 EER25448.1 - 1.6e-09 37.9 0.2 1.9e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EER25448.1 - 5.3e-06 26.8 0.4 6.2e-06 26.6 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EER25448.1 - 2.7e-05 24.3 0.2 3.8e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EER25448.1 - 6.3e-05 23.2 0.2 0.0001 22.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EER25448.1 - 0.00015 22.1 0.1 0.00022 21.5 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EER25448.1 - 0.0025 17.9 0.0 0.003 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EER25448.1 - 0.0069 16.4 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated HIGH_NTase1_ass PF16581.5 EER25448.1 - 0.037 14.0 0.0 0.041 13.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region TFIID_20kDa PF03847.13 EER25448.1 - 0.05 14.1 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Wound_ind PF08186.11 EER25448.1 - 0.076 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Wound-inducible basic protein family Mito_carr PF00153.27 EER25449.1 - 1.5e-25 89.0 0.6 5.9e-08 32.5 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein CRIM PF16978.5 EER25450.1 - 2.8e-42 144.2 0.0 4.8e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EER25450.1 - 7.8e-29 100.2 0.4 2.3e-28 98.7 0.3 1.8 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 EER25450.1 - 0.004 17.3 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 TUG ubiquitin-like domain Pkinase PF00069.25 EER25451.1 - 1.9e-71 240.5 0.0 2.5e-71 240.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25451.1 - 6.7e-37 127.2 0.0 9.1e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER25451.1 - 5.3e-07 29.2 0.0 8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.16 EER25451.1 - 0.04 13.2 0.5 0.098 12.0 0.5 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein zf-Tim10_DDP PF02953.15 EER25452.1 - 5.6e-19 67.5 1.4 7.5e-19 67.2 1.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Lectin_leg-like PF03388.13 EER25453.1 - 7.5e-62 208.7 0.0 1e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 EER25453.1 - 0.0004 20.0 0.0 0.46 10.0 0.0 2.1 2 0 0 2 2 2 2 Legume lectin domain BRF1 PF07741.13 EER25454.1 - 5.6 7.4 27.9 0.29 11.5 7.2 3.5 2 1 1 3 3 3 0 Brf1-like TBP-binding domain PRCC PF10253.9 EER25455.1 - 8e-38 131.4 8.2 8e-38 131.4 8.2 2.9 2 2 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting Sigma70_r4 PF04545.16 EER25455.1 - 0.079 12.5 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 RPAP1_N PF08621.10 EER25455.1 - 0.73 9.6 2.7 0.41 10.5 0.5 1.7 2 0 0 2 2 2 0 RPAP1-like, N-terminal AAA_5 PF07728.14 EER25456.1 - 1.9e-127 419.8 0.0 2e-21 76.4 0.0 9.9 8 1 1 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EER25456.1 - 9.7e-51 170.4 17.4 4.4e-22 78.3 0.1 6.3 6 0 0 6 6 5 4 Midasin AAA lid domain AAA_16 PF13191.6 EER25456.1 - 7e-30 104.6 11.8 9.2e-05 22.9 0.2 8.5 7 2 0 7 7 6 6 AAA ATPase domain AAA_7 PF12775.7 EER25456.1 - 6.1e-29 100.8 0.6 7.8e-05 22.3 0.0 7.1 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 EER25456.1 - 2.7e-28 98.1 0.0 1.8e-27 95.5 0.0 2.6 2 0 0 2 2 1 1 Midasin AAA lid domain AAA_3 PF07726.11 EER25456.1 - 4.8e-28 97.6 0.0 7.4e-11 42.0 0.0 6.9 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EER25456.1 - 3.1e-26 92.4 1.2 0.00028 21.3 0.0 7.4 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 EER25456.1 - 4.4e-22 78.4 0.0 0.0002 21.4 0.0 7.3 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA_22 PF13401.6 EER25456.1 - 4.6e-20 72.3 0.6 0.035 14.4 0.0 8.2 7 0 0 7 7 6 4 AAA domain AAA_6 PF12774.7 EER25456.1 - 1.3e-18 67.0 0.0 0.0035 16.3 0.0 8.9 8 2 0 8 8 8 3 Hydrolytic ATP binding site of dynein motor region Sigma54_activat PF00158.26 EER25456.1 - 7.1e-18 64.9 0.0 0.053 13.2 0.0 6.3 6 0 0 6 6 6 4 Sigma-54 interaction domain TsaE PF02367.17 EER25456.1 - 8.1e-15 54.9 7.4 0.11 12.5 0.1 6.9 7 0 0 7 7 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EER25456.1 - 2.1e-14 54.2 1.0 0.15 12.7 0.0 7.2 6 0 0 6 6 6 2 AAA domain AAA_30 PF13604.6 EER25456.1 - 2.1e-14 53.7 0.0 0.037 13.8 0.0 7.7 8 0 0 8 8 7 2 AAA domain AAA_14 PF13173.6 EER25456.1 - 8.8e-14 51.7 0.0 0.017 15.1 0.0 7.2 7 0 0 7 7 7 2 AAA domain RsgA_GTPase PF03193.16 EER25456.1 - 5.3e-13 49.2 2.5 0.041 13.8 0.0 5.9 6 0 0 6 6 5 2 RsgA GTPase NACHT PF05729.12 EER25456.1 - 2.2e-12 47.2 12.2 0.075 12.9 0.0 7.0 8 0 0 8 8 5 4 NACHT domain RNA_helicase PF00910.22 EER25456.1 - 3.9e-12 46.5 1.5 3.4 8.1 0.0 6.9 6 0 0 6 6 6 0 RNA helicase AAA_33 PF13671.6 EER25456.1 - 4.8e-12 46.2 0.2 0.11 12.7 0.0 6.8 6 0 0 6 6 6 1 AAA domain ABC_tran PF00005.27 EER25456.1 - 1.2e-11 45.3 12.7 0.13 12.8 0.0 7.4 7 1 0 7 7 6 3 ABC transporter Mg_chelatase PF01078.21 EER25456.1 - 5.1e-11 42.4 2.2 1.1 8.6 0.0 8.6 9 1 1 10 10 8 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EER25456.1 - 9.4e-10 38.5 1.2 0.49 10.1 0.0 5.7 5 0 0 5 5 5 2 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 EER25456.1 - 2.4e-09 36.8 1.2 1.4 8.2 0.0 6.8 6 0 0 6 6 6 1 Zeta toxin Rad17 PF03215.15 EER25456.1 - 8.3e-09 35.6 0.5 0.098 12.6 0.0 5.8 6 0 0 6 6 5 1 Rad17 P-loop domain DUF815 PF05673.13 EER25456.1 - 9.3e-09 34.8 2.2 1.9 7.6 0.1 5.9 6 0 0 6 6 6 3 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EER25456.1 - 9.8e-09 35.4 0.5 0.09 12.9 0.0 5.8 6 0 0 6 6 5 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EER25456.1 - 2.5e-08 33.9 0.0 0.83 9.4 0.0 6.2 6 0 0 6 6 6 1 IstB-like ATP binding protein AAA_29 PF13555.6 EER25456.1 - 2.8e-08 33.4 0.7 9.2 6.1 0.0 6.5 6 0 0 6 6 6 0 P-loop containing region of AAA domain AAA_19 PF13245.6 EER25456.1 - 8.8e-08 32.6 4.6 4.6 7.6 0.1 6.4 6 0 0 6 6 5 0 AAA domain SRP54 PF00448.22 EER25456.1 - 1.3e-07 31.4 5.4 1.3 8.6 0.0 5.9 6 0 0 6 6 6 1 SRP54-type protein, GTPase domain Roc PF08477.13 EER25456.1 - 2.2e-07 31.1 2.5 1.5 9.1 0.0 6.1 6 0 0 6 6 6 1 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EER25456.1 - 2.7e-07 30.7 0.0 15 5.4 0.0 6.1 6 0 0 6 6 6 0 ATPase domain predominantly from Archaea TniB PF05621.11 EER25456.1 - 3.9e-07 29.7 0.1 1.2 8.5 0.0 5.8 6 0 0 6 6 6 1 Bacterial TniB protein T2SSE PF00437.20 EER25456.1 - 6e-07 28.8 2.5 0.057 12.5 0.0 5.3 6 0 0 6 6 6 1 Type II/IV secretion system protein AAA_25 PF13481.6 EER25456.1 - 1.6e-06 27.8 6.0 5 6.6 0.1 5.9 5 0 0 5 5 5 0 AAA domain PduV-EutP PF10662.9 EER25456.1 - 1.9e-06 27.7 3.6 0.095 12.4 0.0 5.9 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EER25456.1 - 5.2e-06 26.3 0.7 17 5.0 0.0 6.8 7 1 0 7 7 6 0 AAA domain Bac_DnaA PF00308.18 EER25456.1 - 1.1e-05 25.4 0.2 2.5 7.9 0.0 4.5 4 0 0 4 4 4 1 Bacterial dnaA protein AAA_28 PF13521.6 EER25456.1 - 1.5e-05 25.3 9.6 1.2 9.4 0.1 6.0 6 0 0 6 6 5 1 AAA domain MCM PF00493.23 EER25456.1 - 2.8e-05 23.3 0.0 2.8 7.0 0.0 4.9 6 0 0 6 6 5 1 MCM P-loop domain MMR_HSR1 PF01926.23 EER25456.1 - 0.0003 20.8 3.3 18 5.5 0.0 5.9 6 0 0 6 6 6 0 50S ribosome-binding GTPase ResIII PF04851.15 EER25456.1 - 0.00051 20.1 0.1 8.1 6.4 0.1 4.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 EER25456.1 - 0.001 18.3 2.3 1.6 7.8 0.0 4.4 5 0 0 5 5 5 1 TIP49 P-loop domain CPT PF07931.12 EER25456.1 - 0.0038 17.1 0.3 0.84 9.5 0.0 3.9 4 1 0 4 4 2 1 Chloramphenicol phosphotransferase-like protein ATPase PF06745.13 EER25456.1 - 0.0055 16.1 0.1 7.8 5.8 0.0 3.7 4 0 0 4 4 3 0 KaiC KAP_NTPase PF07693.14 EER25456.1 - 0.0062 15.8 0.0 37 3.4 0.0 4.9 5 0 0 5 5 5 0 KAP family P-loop domain AAA_8 PF12780.7 EER25456.1 - 0.0067 15.8 1.0 26 4.0 0.0 5.0 5 0 0 5 5 5 0 P-loop containing dynein motor region D4 NTPase_1 PF03266.15 EER25456.1 - 0.0069 16.3 8.8 3.5 7.5 0.1 5.2 5 0 0 5 5 4 0 NTPase CbiA PF01656.23 EER25456.1 - 0.015 15.4 0.0 5.4 7.1 0.0 4.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.6 EER25456.1 - 0.018 15.4 5.4 5.9 7.3 0.0 4.5 4 0 0 4 4 3 0 AAA domain DEAD PF00270.29 EER25456.1 - 0.037 13.8 0.1 17 5.2 0.0 3.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase Sas10 PF09368.10 EER25456.1 - 0.038 14.5 0.2 7.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Sas10 C-terminal domain PhoH PF02562.16 EER25456.1 - 0.042 13.3 2.5 4.3 6.7 0.0 4.1 5 0 0 5 5 4 0 PhoH-like protein DnaB_C PF03796.15 EER25456.1 - 0.044 13.1 3.2 4.7 6.5 0.0 4.7 5 0 0 5 5 5 0 DnaB-like helicase C terminal domain Ploopntkinase3 PF18751.1 EER25456.1 - 0.049 13.5 0.1 2.2 8.2 0.0 3.3 4 0 0 4 4 3 0 P-loop Nucleotide Kinase3 Septin PF00735.18 EER25456.1 - 0.21 10.8 1.2 45 3.2 0.1 4.1 4 0 0 4 4 4 0 Septin FeoB_N PF02421.18 EER25456.1 - 0.21 11.1 1.3 38 3.8 0.0 4.1 4 0 0 4 4 4 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EER25456.1 - 0.28 10.9 8.4 48 3.6 0.0 5.4 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein Ras PF00071.22 EER25456.1 - 0.4 10.3 3.9 33 4.0 0.0 4.5 5 0 0 5 5 5 0 Ras family DUF2756 PF10956.8 EER25456.1 - 0.54 10.8 1.9 2.6 8.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2756) dNK PF01712.19 EER25456.1 - 2.5 7.9 4.6 41 3.9 0.0 3.7 5 0 0 5 5 2 0 Deoxynucleoside kinase cobW PF02492.19 EER25456.1 - 2.6 7.6 9.2 34 4.0 0.1 5.2 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain Voltage_CLC PF00654.20 EER25457.1 - 3.6e-88 296.2 23.5 3.6e-88 296.2 23.5 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EER25457.1 - 0.006 17.0 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain P5CR_dimer PF14748.6 EER25458.1 - 9.6e-33 112.5 3.9 1.6e-32 111.8 3.9 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EER25458.1 - 5.7e-11 42.9 0.0 2.7e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent GHMP_kinases_C PF08544.13 EER25458.1 - 0.057 13.8 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 GHMP kinases C terminal CTK3 PF12243.8 EER25459.1 - 6.7e-48 161.8 0.2 9.1e-48 161.3 0.2 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EER25459.1 - 1.4e-20 73.2 9.9 1.4e-20 73.2 9.9 1.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus CARD PF00619.21 EER25459.1 - 0.079 13.0 0.4 0.39 10.8 0.0 2.3 2 1 0 2 2 2 0 Caspase recruitment domain U3_snoRNA_assoc PF08297.11 EER25460.1 - 5e-20 72.0 0.2 5e-20 72.0 0.2 3.6 2 1 0 3 3 3 1 U3 snoRNA associated AAA_23 PF13476.6 EER25460.1 - 0.12 12.8 7.6 0.17 12.3 7.6 1.3 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 EER25460.1 - 0.22 10.0 13.8 0.3 9.5 13.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Abhydrolase_6 PF12697.7 EER25461.1 - 9e-21 75.5 0.1 1.1e-20 75.3 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF155 PF02582.14 EER25462.1 - 3.9e-51 173.6 0.0 8.2e-51 172.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.19 EER25463.1 - 0.077 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box WD40 PF00400.32 EER25464.1 - 6.6e-37 124.9 26.2 1.4e-06 28.9 0.1 7.8 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.7 EER25464.1 - 2e-11 43.6 0.5 4.3e-11 42.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EER25464.1 - 2.4e-09 37.4 0.6 0.06 13.7 0.0 5.6 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER25464.1 - 1.4e-05 24.0 3.3 0.57 8.8 0.1 4.7 1 1 3 6 6 6 3 Nucleoporin Nup120/160 F-box PF00646.33 EER25464.1 - 8.6e-05 22.3 0.8 0.00025 20.8 0.8 1.9 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 EER25464.1 - 0.00012 21.6 0.0 0.019 14.3 0.0 2.5 2 1 2 4 4 4 3 WD40-like domain PQQ_2 PF13360.6 EER25464.1 - 0.02 14.5 3.9 0.75 9.3 3.6 2.8 1 1 0 1 1 1 0 PQQ-like domain F-box_5 PF18511.1 EER25464.1 - 0.041 13.5 0.0 0.095 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box Zip PF02535.22 EER25465.1 - 7.5e-38 130.6 22.4 3.7e-29 102.0 6.7 3.3 2 1 0 2 2 2 2 ZIP Zinc transporter Transp_cyt_pur PF02133.15 EER25466.1 - 4.5e-100 335.5 37.4 5.2e-100 335.3 37.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CcmD PF04995.14 EER25466.1 - 0.16 12.1 2.1 0.28 11.3 0.0 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF917 PF06032.12 EER25467.1 - 3.3e-120 401.1 0.4 1.1e-117 392.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 EER25467.1 - 2.3e-30 105.6 2.8 7.2e-27 94.2 0.1 3.7 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_A PF01968.18 EER25467.1 - 1.9e-25 89.7 9.5 4.4e-24 85.3 1.1 3.4 2 1 1 3 3 3 2 Hydantoinase/oxoprolinase MutL PF13941.6 EER25467.1 - 2.8e-05 22.9 2.0 0.056 12.0 0.6 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.20 EER25467.1 - 0.0058 16.2 0.8 0.0058 16.2 0.8 2.3 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EER25467.1 - 0.034 13.6 0.2 0.034 13.6 0.2 2.1 2 0 0 2 2 2 0 ROK family CM_1 PF07736.11 EER25467.1 - 0.14 12.6 0.0 0.53 10.7 0.0 2.0 1 0 0 1 1 1 0 Chorismate mutase type I Hat1_N PF10394.9 EER25468.1 - 3.6e-51 173.6 0.4 7.6e-51 172.5 0.0 1.7 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Adaptin_binding PF10199.9 EER25469.1 - 0.0091 16.6 0.7 0.016 15.8 0.7 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 MAP65_ASE1 PF03999.12 EER25469.1 - 0.023 13.4 1.0 0.036 12.8 1.0 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) LSM PF01423.22 EER25470.1 - 1.4e-17 63.1 0.0 2.2e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EER25470.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.11 EER25470.1 - 0.016 14.1 4.1 0.015 14.1 4.1 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DSPc PF00782.20 EER25471.1 - 6.5e-10 38.9 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EER25471.1 - 0.0088 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EER25471.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family HTH_26 PF13443.6 EER25472.1 - 0.00017 21.9 0.3 0.14 12.6 0.2 2.2 2 0 0 2 2 2 2 Cro/C1-type HTH DNA-binding domain HTH_31 PF13560.6 EER25472.1 - 0.0064 16.8 0.1 0.031 14.6 0.1 2.0 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 EER25472.1 - 0.025 15.2 0.0 0.089 13.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.6 EER25472.1 - 0.027 14.5 0.1 0.046 13.8 0.1 1.5 1 1 0 1 1 1 0 Winged helix-turn helix HTH_Mga PF08280.11 EER25472.1 - 0.033 14.2 0.0 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain HTH_23 PF13384.6 EER25472.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain HTH_6 PF01418.17 EER25472.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family PPR_2 PF13041.6 EER25473.1 - 1.3e-15 57.3 0.0 5.4e-05 23.3 0.1 6.6 6 2 1 7 7 7 4 PPR repeat family PPR_3 PF13812.6 EER25473.1 - 1.4e-13 50.7 0.9 0.039 14.0 0.0 5.8 3 2 4 7 7 7 5 Pentatricopeptide repeat domain PPR PF01535.20 EER25473.1 - 1.2e-12 47.1 5.3 0.52 10.7 0.1 8.1 9 0 0 9 9 9 4 PPR repeat PPR_long PF17177.4 EER25473.1 - 3.6e-12 46.1 0.3 1.8e-05 24.2 0.0 3.9 1 1 2 3 3 3 3 Pentacotripeptide-repeat region of PRORP Umbravirus_LDM PF04817.12 EER25473.1 - 0.012 15.0 1.1 0.024 14.0 1.1 1.4 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family PPR_1 PF12854.7 EER25473.1 - 0.26 11.0 0.7 96 2.8 0.0 4.3 5 0 0 5 5 5 0 PPR repeat PLA2_B PF01735.18 EER25474.1 - 9.4e-24 83.7 0.0 1.6e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.15 EER25475.1 - 2.9e-88 296.4 0.0 4.5e-88 295.8 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit APH PF01636.23 EER25477.1 - 6.3e-15 55.8 0.0 2e-14 54.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER25477.1 - 0.00025 20.7 1.4 0.00034 20.3 0.1 1.8 2 1 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 EER25477.1 - 0.12 11.8 0.2 0.33 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein kinase domain BCDHK_Adom3 PF10436.9 EER25478.1 - 8.8e-75 250.0 0.0 1.3e-74 249.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EER25478.1 - 1.3e-13 51.4 0.0 2.9e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EER25478.1 - 0.007 16.2 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VSP PF03302.13 EER25479.1 - 0.00024 20.1 0.2 0.00024 20.1 0.2 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein Mid2 PF04478.12 EER25479.1 - 0.014 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Podoplanin PF05808.11 EER25479.1 - 0.039 14.1 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 Podoplanin SKN1 PF03935.15 EER25480.1 - 1.3e-229 762.8 0.1 1.5e-229 762.6 0.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Na_H_Exchanger PF00999.21 EER25481.1 - 3.7e-40 137.9 12.0 4.9e-40 137.5 12.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EER25481.1 - 0.0014 18.7 0.2 0.013 15.5 0.1 2.7 2 0 0 2 2 2 1 YrhC-like protein COX1 PF00115.20 EER25481.1 - 0.64 8.8 11.6 0.043 12.7 5.5 2.1 2 0 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I PhaG_MnhG_YufB PF03334.14 EER25481.1 - 1.2 9.5 12.2 16 5.8 0.6 4.2 3 1 0 3 3 3 0 Na+/H+ antiporter subunit DUF3382 PF11862.8 EER25481.1 - 7.2 7.0 8.4 0.28 11.5 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3382) NuiA PF07924.11 EER25482.1 - 0.11 12.8 0.0 2.7 8.4 0.0 2.2 1 1 0 1 1 1 0 Nuclease A inhibitor-like protein Ribosomal_L3 PF00297.22 EER25483.1 - 4e-185 615.1 8.2 4.5e-185 614.9 8.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.28 EER25484.1 - 3.9e-53 175.2 34.6 5.5e-08 32.3 0.1 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.17 EER25484.1 - 8.8e-47 153.5 26.3 1.2e-05 25.0 0.0 10.6 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EER25484.1 - 2.9e-35 117.5 23.5 1.5e-07 31.0 0.0 10.7 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 EER25484.1 - 5.1e-26 90.1 22.7 4.3e-05 23.1 1.5 9.6 6 2 3 9 9 9 7 TPR repeat TPR_16 PF13432.6 EER25484.1 - 2.3e-25 89.0 12.3 8.1e-06 26.4 0.1 8.1 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 EER25484.1 - 2.9e-25 88.5 14.7 0.00028 21.3 0.2 7.3 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 EER25484.1 - 6.4e-25 85.7 20.6 0.0013 18.9 0.1 10.7 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.6 EER25484.1 - 1.5e-22 78.4 18.5 0.00034 21.2 0.1 9.5 6 3 4 10 10 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 EER25484.1 - 5.9e-21 74.5 20.9 0.00015 21.9 0.9 7.7 3 2 3 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EER25484.1 - 5.6e-19 67.5 16.7 0.012 16.3 0.0 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 EER25484.1 - 6.4e-18 63.4 14.7 0.029 14.4 0.1 9.4 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 EER25484.1 - 1.5e-14 53.9 9.1 0.0051 16.9 0.2 7.2 2 1 5 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EER25484.1 - 2.9e-12 46.6 12.9 1.5e-08 34.8 3.4 4.2 4 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EER25484.1 - 1.4e-07 31.0 9.5 0.15 11.2 0.1 5.5 1 1 6 7 7 7 3 Tetratricopeptide repeat TPR_21 PF09976.9 EER25484.1 - 3.8e-06 26.7 7.9 0.027 14.2 0.0 4.9 4 2 1 5 5 5 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 EER25484.1 - 0.00057 20.3 4.7 8.9 6.7 0.1 3.8 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EER25484.1 - 0.0018 17.8 4.9 0.67 9.3 0.0 3.7 2 2 2 4 4 4 2 MalT-like TPR region TPR_20 PF14561.6 EER25484.1 - 0.0031 17.8 1.1 0.47 10.8 0.1 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.9 EER25484.1 - 0.011 15.5 2.8 0.27 10.9 0.0 3.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 EER25484.1 - 0.19 11.6 10.9 29 4.7 0.2 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat DUF410 PF04190.13 EER25484.1 - 0.4 10.4 3.2 15 5.2 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF410) TPR_3 PF07720.12 EER25484.1 - 0.43 10.6 15.8 35 4.5 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.10 EER25484.1 - 0.55 9.2 2.3 6.8 5.6 0.4 2.8 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) NUC173 PF08161.12 EER25485.1 - 1.2e-80 270.0 0.1 8.5e-78 260.7 0.0 3.4 3 0 0 3 3 3 2 NUC173 domain HEAT_2 PF13646.6 EER25485.1 - 0.0093 16.3 1.7 0.22 11.9 0.3 3.7 3 0 0 3 3 3 1 HEAT repeats CLASP_N PF12348.8 EER25485.1 - 0.035 13.7 0.0 13 5.3 0.0 3.6 4 0 0 4 4 4 0 CLASP N terminal CdiI_2 PF18593.1 EER25485.1 - 0.11 13.2 0.2 41 4.9 0.0 3.9 5 0 0 5 5 5 0 CdiI immunity protein HEAT PF02985.22 EER25485.1 - 0.17 12.2 4.3 27 5.4 0.1 4.6 4 0 0 4 4 4 0 HEAT repeat Vac14_Fab1_bd PF12755.7 EER25485.1 - 0.21 12.2 0.6 18 6.0 0.1 3.7 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region LSM PF01423.22 EER25486.1 - 7e-16 57.7 0.1 9.7e-16 57.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain Ribonuclease_3 PF00636.26 EER25487.1 - 3.7e-39 133.6 0.0 4.2e-20 72.3 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EER25487.1 - 1.4e-24 86.6 0.0 1.3e-12 48.0 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 EER25487.1 - 2.4e-20 72.5 0.0 6.1e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 EER25487.1 - 7.5e-19 68.2 0.0 1.9e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER25487.1 - 1.5e-15 57.5 0.1 4e-15 56.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER25487.1 - 2.6e-12 47.1 0.0 5.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EER25487.1 - 0.029 14.6 0.0 0.098 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Proteasome PF00227.26 EER25488.1 - 4.8e-58 195.8 0.0 1.8e-33 115.7 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EER25488.1 - 9.3e-11 41.2 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.7 EER25489.1 - 6.2e-09 35.9 4.1 7e-09 35.7 0.7 2.3 2 0 0 2 2 2 1 RING-variant domain PHD_4 PF16866.5 EER25489.1 - 0.00018 21.5 2.9 0.25 11.5 1.8 2.3 2 0 0 2 2 2 2 PHD-finger DUF2752 PF10825.8 EER25489.1 - 0.017 15.1 2.0 0.035 14.1 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) DUF4079 PF13301.6 EER25489.1 - 0.06 13.5 0.1 0.25 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) zf-RING_2 PF13639.6 EER25489.1 - 0.18 12.2 5.1 1.2 9.6 1.6 2.3 2 0 0 2 2 2 0 Ring finger domain DUF3951 PF13131.6 EER25489.1 - 0.26 11.5 3.2 0.62 10.3 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) Zf_RING PF16744.5 EER25489.1 - 5.9 7.1 8.8 48 4.2 1.6 4.0 4 1 0 4 4 4 0 KIAA1045 RING finger Aldo_ket_red PF00248.21 EER25490.1 - 2.5e-42 145.1 0.0 2.9e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RecG_wedge PF17191.4 EER25490.1 - 0.034 13.8 0.2 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 RecG wedge domain FlgN PF05130.12 EER25491.1 - 0.054 14.0 1.4 0.086 13.4 0.3 1.9 2 0 0 2 2 2 0 FlgN protein Fungal_trans PF04082.18 EER25492.1 - 4.9e-08 32.3 0.2 1.2e-07 31.0 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER25492.1 - 0.0035 17.4 11.3 0.0035 17.4 11.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EER25494.1 - 7.6e-87 292.0 25.2 9.2e-87 291.8 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER25494.1 - 1.8e-13 50.2 44.6 5.8e-13 48.5 31.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_1 PF00300.22 EER25495.1 - 9.9e-29 100.4 0.1 1.4e-28 99.9 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 EER25496.1 - 6.1e-78 261.2 0.0 8.9e-78 260.6 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EER25496.1 - 3.2e-39 134.6 0.0 5.6e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EER25496.1 - 0.00025 21.2 0.0 0.00053 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EER25496.1 - 0.0013 18.2 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Vps39_2 PF10367.9 EER25497.1 - 5.6e-30 104.0 0.0 1.5e-29 102.6 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EER25497.1 - 1.3e-29 102.6 0.0 1.7e-28 99.0 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 EER25497.1 - 2.7e-15 56.7 0.0 9.2e-15 55.0 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 EER25497.1 - 8.3e-08 32.2 1.0 3.3e-05 23.8 0.1 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS Gon7 PF08738.10 EER25498.1 - 3.9e-17 62.3 3.1 2.3e-16 59.8 3.1 1.8 1 1 0 1 1 1 1 Gon7 family APH PF01636.23 EER25499.1 - 2.1e-15 57.3 0.0 3.2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER25499.1 - 0.00025 20.7 0.0 0.00036 20.2 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.17 EER25499.1 - 0.022 14.1 0.0 4.3 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase RIO1 PF01163.22 EER25499.1 - 0.023 14.3 0.0 0.063 12.9 0.0 1.7 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 EER25499.1 - 0.087 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Metallophos PF00149.28 EER25500.1 - 7.6e-13 49.4 5.5 1.5e-12 48.5 5.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EER25500.1 - 2.2e-07 31.2 1.1 8.3e-07 29.3 1.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2204 PF09970.9 EER25501.1 - 3.8e-05 23.4 0.0 5.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) Catalase_C PF18011.1 EER25501.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases HbrB PF08539.11 EER25502.1 - 1.1e-47 162.2 0.0 3e-47 160.8 0.0 1.8 1 0 0 1 1 1 1 HbrB-like FliX PF10768.9 EER25502.1 - 8.6 6.9 6.4 1.1 9.8 1.2 2.2 2 0 0 2 2 2 0 Class II flagellar assembly regulator K1377 PF15352.6 EER25503.1 - 0.37 9.0 0.0 0.48 8.6 0.0 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Myb_DNA-bind_6 PF13921.6 EER25504.1 - 5.4e-06 26.6 1.0 0.12 12.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EER25504.1 - 0.0025 18.8 2.2 0.031 15.2 0.3 2.3 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain RBR PF17208.3 EER25504.1 - 0.0096 16.6 4.1 0.0096 16.6 4.1 2.4 2 0 0 2 2 2 1 RNA binding Region Myb_DNA-binding PF00249.31 EER25504.1 - 0.046 13.9 2.0 3.9 7.7 0.2 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EER25504.1 - 0.067 13.3 2.7 6.4 6.9 0.2 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain AAA PF00004.29 EER25505.1 - 2e-16 60.6 0.0 5.2e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EER25505.1 - 0.00026 21.0 0.0 0.00079 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EER25505.1 - 0.001 19.3 0.6 0.014 15.7 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EER25505.1 - 0.0027 18.1 1.0 0.007 16.8 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 EER25505.1 - 0.013 15.8 0.1 0.042 14.2 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EER25505.1 - 0.037 13.8 0.0 0.037 13.8 0.0 3.7 2 1 2 4 4 4 0 AAA domain DUF5320 PF17253.2 EER25505.1 - 0.12 13.4 2.4 0.58 11.3 2.4 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5320) AAA_33 PF13671.6 EER25505.1 - 0.2 11.8 3.1 0.18 11.9 0.2 2.6 2 1 0 2 2 2 0 AAA domain Sec7 PF01369.20 EER25506.1 - 2.8e-65 219.4 0.1 7.9e-65 218.0 0.1 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EER25506.1 - 2.5e-43 147.7 5.8 2.5e-43 147.7 5.8 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EER25506.1 - 1.9e-34 117.3 10.1 1.7e-32 111.1 0.1 6.1 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 EER25506.1 - 5.6e-17 62.0 1.7 8.2e-16 58.2 0.0 3.1 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Rcd1 PF04078.13 EER25506.1 - 0.27 10.5 4.4 0.18 11.1 0.1 2.6 3 0 0 3 3 3 0 Cell differentiation family, Rcd1-like 2-oxoacid_dh PF00198.23 EER25507.1 - 4.8e-75 252.0 0.1 6.1e-75 251.7 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EER25507.1 - 9.4e-18 63.8 0.8 9.4e-18 63.8 0.8 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 EER25507.1 - 1.2e-14 54.4 0.7 3.3e-14 52.9 0.7 1.9 1 0 0 1 1 1 1 e3 binding domain DUF421 PF04239.12 EER25507.1 - 0.011 15.4 0.1 0.03 14.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF421) SopE_GEF PF07487.13 EER25507.1 - 0.058 13.5 0.0 0.17 12.0 0.0 1.7 2 0 0 2 2 2 0 SopE GEF domain DUF5353 PF17304.2 EER25508.1 - 2.9e-32 110.2 3.4 4.1e-32 109.7 3.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Ntox3 PF15536.6 EER25508.1 - 0.11 12.5 0.3 0.16 12.0 0.3 1.1 1 0 0 1 1 1 0 Bacterial toxin 3 V-SNARE_C PF12352.8 EER25509.1 - 8.5e-14 51.6 0.3 1.9e-13 50.5 0.3 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EER25509.1 - 0.0048 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.16 EER25509.1 - 0.012 15.1 1.6 0.013 15.0 0.3 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_DeoR PF08220.12 EER25509.1 - 0.029 14.1 0.1 0.8 9.5 0.0 2.2 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain Vps5 PF09325.10 EER25509.1 - 0.035 13.6 0.5 0.063 12.8 0.5 1.3 1 0 0 1 1 1 0 Vps5 C terminal like PDR_assoc PF08370.11 EER25509.1 - 0.082 12.7 0.2 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Plant PDR ABC transporter associated TPR_MLP1_2 PF07926.12 EER25509.1 - 0.28 11.3 3.2 0.61 10.2 1.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0220 PF05255.11 EER25510.1 - 0.4 10.2 6.1 1.3 8.6 1.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) Ldh_1_C PF02866.18 EER25511.1 - 3.3e-48 163.8 0.0 1.4e-47 161.8 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EER25511.1 - 5.8e-43 146.4 0.1 9.5e-43 145.7 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EER25511.1 - 0.00072 18.6 0.0 0.001 18.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 EER25511.1 - 0.037 13.3 0.1 0.24 10.7 0.0 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.16 EER25511.1 - 0.049 13.2 0.1 4.3 6.8 0.2 2.5 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase NAD_binding_7 PF13241.6 EER25512.1 - 3.7e-31 107.6 0.1 6.4e-31 106.9 0.1 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EER25512.1 - 3.1e-30 103.6 0.0 4.7e-30 103.0 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EER25512.1 - 6.7e-15 54.2 0.1 1.4e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 EER25512.1 - 0.0034 16.7 0.0 0.0048 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EER25512.1 - 0.078 12.3 1.8 0.24 10.8 0.2 2.1 1 1 1 2 2 2 0 ThiF family LSDAT_prok PF18171.1 EER25512.1 - 0.083 12.1 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Pribosyltran_N PF13793.6 EER25513.1 - 4.2e-44 149.2 0.2 1.2e-41 141.2 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EER25513.1 - 9.7e-36 123.5 0.2 1.2e-30 107.0 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EER25513.1 - 1.1e-10 41.3 0.1 1.3e-07 31.3 0.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain CbiJ PF02571.14 EER25513.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Methyltransf_10 PF05971.12 EER25514.1 - 1.9e-63 214.6 0.0 6e-63 213.0 0.0 1.8 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EER25514.1 - 2.9e-05 23.7 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TrmK PF04816.12 EER25514.1 - 0.00057 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_18 PF12847.7 EER25514.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EER25514.1 - 0.0055 16.1 0.0 0.0099 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EER25514.1 - 0.0071 17.0 0.0 0.019 15.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EER25514.1 - 0.025 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 EER25514.1 - 0.026 15.2 0.0 0.067 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EER25514.1 - 0.035 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_4 PF02390.17 EER25514.1 - 0.08 12.4 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.6 EER25514.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.15 EER25515.1 - 1.7e-06 27.9 0.8 3e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EER25515.1 - 0.028 15.2 0.6 0.061 14.1 0.4 1.7 1 1 0 1 1 1 0 Complex1_LYR-like Ank_4 PF13637.6 EER25516.1 - 4.3e-10 39.9 2.6 1.2e-08 35.3 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER25516.1 - 0.00031 21.3 0.8 0.027 15.0 1.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) KilA-N PF04383.13 EER25516.1 - 0.0021 17.9 2.3 0.012 15.5 0.2 2.7 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.6 EER25516.1 - 0.0056 17.1 4.3 0.14 12.8 0.2 3.8 4 1 0 4 4 3 1 Ankyrin repeat PhoU PF01895.19 EER25516.1 - 0.12 12.9 6.7 0.17 12.4 2.6 2.7 3 0 0 3 3 3 0 PhoU domain Stn1 PF10451.9 EER25516.1 - 0.13 11.2 1.1 0.27 10.2 1.1 1.4 1 0 0 1 1 1 0 Telomere regulation protein Stn1 AAA_13 PF13166.6 EER25516.1 - 0.35 9.4 8.5 0.23 10.1 6.3 1.6 2 0 0 2 2 2 0 AAA domain Ank_5 PF13857.6 EER25516.1 - 0.82 10.1 3.0 3 8.3 0.2 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 EER25516.1 - 3.2 8.4 5.8 25 5.5 0.6 3.5 3 0 0 3 3 3 0 Ankyrin repeat THOC7 PF05615.13 EER25516.1 - 4.1 7.7 14.8 4 7.7 8.2 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Exonuc_VII_L PF02601.15 EER25516.1 - 6.1 6.3 12.5 0.22 11.1 5.9 1.8 2 1 1 3 3 3 0 Exonuclease VII, large subunit IMUP PF15761.5 EER25517.1 - 0.00074 20.2 14.9 0.0017 19.0 14.9 1.6 1 0 0 1 1 1 1 Immortalisation up-regulated protein Rick_17kDa_Anti PF05433.15 EER25517.1 - 0.00076 19.3 25.8 0.0013 18.6 25.8 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain SR-25 PF10500.9 EER25517.1 - 0.0057 16.3 15.4 0.0077 15.9 15.4 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Gly-zipper_Omp PF13488.6 EER25517.1 - 0.01 15.8 17.2 0.023 14.7 17.2 1.6 1 0 0 1 1 1 0 Glycine zipper DUF3824 PF12868.7 EER25517.1 - 0.044 14.5 1.2 0.044 14.5 1.2 3.6 2 1 1 3 3 3 0 Domain of unknwon function (DUF3824) DUF755 PF05501.11 EER25517.1 - 0.059 13.6 24.3 0.1 12.9 24.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP3D1 PF06375.11 EER25517.1 - 6 7.1 13.4 9.6 6.4 13.4 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 AF-4 PF05110.13 EER25517.1 - 7.2 4.6 15.9 11 3.9 15.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF1275 PF06912.11 EER25518.1 - 1.5e-42 145.8 14.8 1.7e-42 145.5 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) adh_short_C2 PF13561.6 EER25519.1 - 5.1e-52 176.8 0.0 6.3e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER25519.1 - 6.1e-46 156.3 0.0 7.9e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER25519.1 - 5.6e-12 45.9 0.1 9.7e-12 45.2 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EER25519.1 - 0.00012 21.5 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 EER25519.1 - 0.0003 20.8 0.4 0.0021 18.0 0.1 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EER25519.1 - 0.011 15.2 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EER25519.1 - 0.039 13.4 0.1 0.35 10.3 0.1 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EER25519.1 - 0.039 13.3 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 EER25519.1 - 0.099 12.5 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EER25519.1 - 0.1 13.0 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EER25519.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ABC_tran PF00005.27 EER25520.1 - 2e-47 161.1 0.1 4e-24 85.7 0.0 3.7 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EER25520.1 - 2.2e-30 104.5 0.3 7.2e-30 102.9 0.3 2.0 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EER25520.1 - 1.3e-16 61.4 2.2 0.0022 17.8 0.1 5.0 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EER25520.1 - 2e-15 56.8 0.0 4.4e-06 26.3 0.0 3.7 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EER25520.1 - 5.7e-10 40.0 3.3 6.8e-05 23.5 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EER25520.1 - 1.9e-08 33.9 0.2 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EER25520.1 - 5.7e-07 29.6 0.0 0.0033 17.3 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EER25520.1 - 2.1e-06 27.8 0.0 0.01 15.9 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EER25520.1 - 2.4e-06 27.9 0.0 0.035 14.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EER25520.1 - 6e-06 26.8 0.1 0.18 12.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EER25520.1 - 7.2e-06 26.3 0.0 0.13 12.5 0.0 3.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EER25520.1 - 1.7e-05 25.3 3.1 0.35 11.2 0.0 4.5 4 1 0 4 4 4 2 AAA ATPase domain AAA PF00004.29 EER25520.1 - 1.9e-05 25.1 0.0 0.78 10.2 0.0 4.5 6 0 0 6 6 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 EER25520.1 - 2.3e-05 23.5 0.1 0.072 12.1 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EER25520.1 - 3.4e-05 24.0 0.1 0.0016 18.5 0.0 3.0 3 0 0 3 3 2 1 Dynamin family PduV-EutP PF10662.9 EER25520.1 - 7.1e-05 22.6 0.0 0.12 12.1 0.0 2.9 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 EER25520.1 - 0.00013 22.1 0.0 0.72 9.9 0.0 3.3 2 0 0 2 2 2 2 Helicase HerA, central domain NACHT PF05729.12 EER25520.1 - 0.00013 21.9 0.0 0.071 13.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EER25520.1 - 0.00017 21.9 0.0 0.7 10.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.6 EER25520.1 - 0.00019 21.3 2.3 0.71 9.5 0.0 3.6 4 1 0 4 4 3 2 AAA ATPase domain AAA_27 PF13514.6 EER25520.1 - 0.00056 19.6 0.4 0.29 10.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain HEAT_2 PF13646.6 EER25520.1 - 0.00087 19.6 0.3 3.8 8.0 0.9 3.2 2 1 1 3 3 3 0 HEAT repeats AAA_24 PF13479.6 EER25520.1 - 0.00095 18.9 0.0 1.4 8.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EER25520.1 - 0.001 19.2 0.0 1.9 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 EER25520.1 - 0.0014 17.8 0.1 1.8 7.6 0.0 2.8 3 0 0 3 3 3 2 G-protein alpha subunit NB-ARC PF00931.22 EER25520.1 - 0.0016 17.7 0.3 0.086 12.0 0.0 2.7 3 0 0 3 3 2 1 NB-ARC domain AAA_14 PF13173.6 EER25520.1 - 0.002 18.2 0.0 3.9 7.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 EER25520.1 - 0.0039 17.4 0.0 1.5 9.2 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EER25520.1 - 0.0044 16.7 0.0 2.3 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 EER25520.1 - 0.0053 16.7 0.0 3.4 7.6 0.0 3.3 3 0 0 3 3 3 1 Rad17 P-loop domain CLP1_P PF16575.5 EER25520.1 - 0.009 15.8 0.2 1.4 8.6 0.0 3.0 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 EER25520.1 - 0.013 15.3 0.0 6.5 6.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EER25520.1 - 0.013 15.1 0.0 8.4 5.9 0.0 3.2 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ParcG PF10274.9 EER25520.1 - 0.016 15.3 3.6 3.3 7.8 0.1 3.4 2 1 1 3 3 3 0 Parkin co-regulated protein ATP-synt_ab PF00006.25 EER25520.1 - 0.019 14.6 0.0 7 6.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 EER25520.1 - 0.022 15.0 0.0 11 6.3 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Mg_chelatase PF01078.21 EER25520.1 - 0.024 14.0 0.7 7.5 5.9 0.0 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Cytidylate_kin PF02224.18 EER25520.1 - 0.026 14.3 0.0 4 7.1 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase HEAT_EZ PF13513.6 EER25520.1 - 0.03 14.8 5.6 23 5.6 0.5 5.3 4 1 1 5 5 5 0 HEAT-like repeat ATPase_2 PF01637.18 EER25520.1 - 0.037 13.9 0.0 3 7.7 0.0 3.0 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea MukB PF04310.12 EER25520.1 - 0.044 13.6 0.0 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 MukB N-terminal IstB_IS21 PF01695.17 EER25520.1 - 0.061 13.1 0.0 13 5.5 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 EER25520.1 - 0.084 12.4 0.0 8.4 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_13 PF13166.6 EER25520.1 - 0.084 11.5 4.2 2.9 6.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 EER25520.1 - 0.088 12.7 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 T2SSE PF00437.20 EER25520.1 - 0.1 11.7 0.5 5.6 5.9 0.0 2.8 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_PrkA PF08298.11 EER25520.1 - 0.1 11.5 0.0 32 3.3 0.0 3.0 3 0 0 3 3 3 0 PrkA AAA domain DUF815 PF05673.13 EER25520.1 - 0.1 11.7 0.0 12 5.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 EER25520.1 - 0.11 12.5 0.0 18 5.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mu-like_Pro PF10123.9 EER25520.1 - 0.19 11.2 4.4 0.49 9.9 4.4 1.7 1 0 0 1 1 1 0 Mu-like prophage I protein Pkinase PF00069.25 EER25521.1 - 1.6e-14 53.9 0.0 1.3e-12 47.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER25521.1 - 0.0061 15.9 0.0 0.015 14.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_1 PF00515.28 EER25522.1 - 6e-05 22.7 7.1 0.049 13.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EER25522.1 - 0.00061 19.4 0.1 0.096 12.4 0.0 2.8 1 1 1 2 2 2 1 TPR repeat TPR_9 PF13371.6 EER25522.1 - 0.0017 18.5 4.8 0.34 11.1 0.1 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER25522.1 - 0.01 15.8 4.8 1.3 9.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EER25522.1 - 0.031 14.7 0.5 37 5.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EER25522.1 - 0.057 14.1 0.0 0.057 14.1 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Lipocalin_2 PF08212.12 EER25522.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Lipocalin-like domain ANAPC3 PF12895.7 EER25522.1 - 0.13 12.5 1.0 0.59 10.4 0.7 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EER25522.1 - 0.13 12.4 17.1 0.18 12.0 0.0 5.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EER25522.1 - 0.19 12.0 2.8 58 4.3 0.9 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Shisa PF13908.6 EER25523.1 - 0.0023 18.2 2.1 0.0023 18.2 2.1 1.5 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Tmemb_9 PF05434.11 EER25523.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.6 2 0 0 2 2 2 0 TMEM9 DUF1700 PF08006.11 EER25523.1 - 0.045 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Asp5 PF17000.5 EER25523.1 - 0.57 10.4 5.8 23 5.2 0.0 2.4 2 0 0 2 2 2 0 Accessory secretory protein Sec, Asp5 DEC-1_N PF04625.13 EER25523.1 - 2.8 6.9 5.9 4.2 6.3 5.9 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region UCH PF00443.29 EER25525.1 - 3.3e-72 243.1 0.0 4.8e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EER25525.1 - 1.6e-12 47.9 0.0 4.9e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EER25525.1 - 4.2e-11 43.0 0.0 0.0004 20.1 0.0 3.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EER25525.1 - 0.00039 20.2 0.0 0.0073 16.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal PX PF00787.24 EER25526.1 - 9.8e-18 64.2 0.0 6e-17 61.7 0.0 2.3 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 EER25526.1 - 4.3e-09 36.3 10.4 6.9e-06 25.8 1.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like IMD PF08397.11 EER25526.1 - 1 8.7 5.0 13 5.1 0.1 2.7 3 0 0 3 3 3 0 IRSp53/MIM homology domain DUF2428 PF10350.9 EER25527.1 - 5e-62 209.7 0.0 1e-61 208.6 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EER25527.1 - 0.23 11.8 0.9 72 4.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat Tim17 PF02466.19 EER25528.1 - 2.5e-27 95.5 1.9 3.4e-27 95.0 1.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family WHAMM-JMY_N PF15920.5 EER25529.1 - 0.23 11.3 0.8 0.87 9.5 0.0 2.4 3 0 0 3 3 3 0 N-terminal of Junction-mediating and WASP homolog-associated Pkinase PF00069.25 EER25530.1 - 5.5e-43 147.2 0.0 2.3e-42 145.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25530.1 - 5e-27 94.8 0.0 6.8e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER25530.1 - 0.00012 21.0 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EER25530.1 - 0.043 13.7 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EER25530.1 - 0.11 11.8 0.0 8.9 5.5 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EER25530.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LVIVD PF08309.11 EER25531.1 - 1.5e-05 24.2 0.6 0.66 9.3 0.0 4.2 4 0 0 4 4 4 3 LVIVD repeat PQQ_3 PF13570.6 EER25531.1 - 0.043 14.3 0.0 2.2 8.9 0.0 2.9 3 0 0 3 3 3 0 PQQ-like domain ILVD_EDD PF00920.21 EER25532.1 - 9.4e-213 707.5 0.5 1.1e-212 707.3 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family Lipase_3 PF01764.25 EER25533.1 - 1.6e-19 70.2 0.0 2.8e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EER25533.1 - 0.0019 18.8 0.0 0.0035 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.8 EER25533.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RAI16-like PF10257.9 EER25534.1 - 5.1e-84 282.2 0.0 7.9e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein UbiA PF01040.18 EER25534.1 - 0.065 12.5 0.3 0.11 11.7 0.3 1.3 1 0 0 1 1 1 0 UbiA prenyltransferase family CBFD_NFYB_HMF PF00808.23 EER25535.1 - 3.1e-14 53.0 3.1 5.7e-14 52.2 3.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EER25535.1 - 0.0027 18.0 6.8 0.0027 18.0 6.8 2.8 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 zf-C3HC4_3 PF13920.6 EER25536.1 - 0.0021 17.9 11.2 0.0037 17.1 11.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CTP_synth_N PF06418.14 EER25537.1 - 3.5e-101 338.0 0.1 4.6e-101 337.6 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EER25537.1 - 6.3e-55 185.9 0.0 1e-54 185.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EER25537.1 - 0.00012 21.9 0.1 0.051 13.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase C26 DUF2469 PF10611.9 EER25537.1 - 0.16 12.5 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) DUF1899 PF08953.11 EER25538.1 - 7.8e-34 115.4 0.1 1.9e-33 114.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EER25538.1 - 3.4e-19 68.4 0.2 6.1e-19 67.7 0.2 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EER25538.1 - 8.1e-16 58.1 6.4 0.0002 22.1 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25538.1 - 6.1e-09 36.1 0.0 0.00017 21.8 0.1 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER25538.1 - 0.039 12.6 0.1 0.18 10.4 0.1 1.9 1 1 1 2 2 2 0 Nucleoporin Nup120/160 eIF2A PF08662.11 EER25538.1 - 0.16 11.8 0.0 2.3 8.0 0.0 2.4 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A SlyX PF04102.12 EER25538.1 - 0.3 11.7 2.8 0.41 11.3 0.9 2.0 2 0 0 2 2 2 0 SlyX p450 PF00067.22 EER25539.1 - 6.5e-55 186.7 0.0 1.4e-49 169.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Kinesin PF00225.23 EER25540.1 - 1.1e-104 349.9 4.0 1.7e-103 346.0 0.2 2.4 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EER25540.1 - 3.5e-59 199.0 0.2 1.1e-58 197.4 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_16 PF13191.6 EER25540.1 - 0.19 12.1 0.0 0.19 12.1 0.0 3.0 2 1 1 3 3 3 0 AAA ATPase domain THOC7 PF05615.13 EER25540.1 - 1.1 9.5 45.4 0.98 9.7 6.4 4.2 2 1 2 4 4 4 0 Tho complex subunit 7 T3SSipB PF16535.5 EER25540.1 - 1.3 9.4 10.0 0.23 11.9 0.1 3.0 3 0 0 3 3 3 0 Type III cell invasion protein SipB YnfE PF17452.2 EER25540.1 - 4.4 7.7 5.4 3.8 7.9 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized YnfE-like Tn7_Tnp_TnsA_C PF08721.11 EER25540.1 - 4.7 7.9 9.5 2 9.1 1.5 3.9 3 1 0 3 3 3 0 TnsA endonuclease C terminal Filament PF00038.21 EER25540.1 - 5.7 6.4 46.2 0.8 9.2 16.3 4.0 2 1 2 4 4 4 0 Intermediate filament protein Abhydrolase_1 PF00561.20 EER25541.1 - 4.3e-21 75.7 0.0 1.7e-20 73.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER25541.1 - 2.4e-10 41.4 0.0 3.3e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER25541.1 - 2e-06 27.3 0.0 2e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EER25541.1 - 0.0051 16.9 0.1 0.013 15.6 0.1 1.5 1 1 0 1 1 1 1 Thioesterase domain Sugar_tr PF00083.24 EER25542.1 - 6.6e-80 269.2 18.6 7.9e-80 268.9 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER25542.1 - 1.1e-15 57.5 17.7 1.1e-15 57.5 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2456 PF10445.9 EER25542.1 - 7.5 6.7 9.9 5.5 7.1 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) RTA1 PF04479.13 EER25544.1 - 1.4e-69 233.8 14.5 2.2e-69 233.2 14.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 EER25545.1 - 8.7e-06 25.8 19.2 1.4e-05 25.1 19.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EER25545.1 - 0.001 17.9 0.3 0.0016 17.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sec66 PF09802.9 EER25545.1 - 0.081 12.5 0.0 0.38 10.3 0.0 1.9 1 1 1 2 2 2 0 Preprotein translocase subunit Sec66 Ank_2 PF12796.7 EER25546.1 - 3.2e-38 130.2 1.7 5.3e-14 52.6 0.0 3.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER25546.1 - 6.7e-25 87.1 0.4 4.2e-09 36.8 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EER25546.1 - 1.1e-22 79.7 5.0 5.7e-10 39.3 0.2 4.7 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER25546.1 - 2.1e-22 76.8 0.6 0.00048 20.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 EER25546.1 - 8.2e-17 60.8 4.9 0.00012 22.3 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat FCD PF07729.12 EER25546.1 - 0.0075 16.7 0.2 4.5 7.7 0.0 2.9 2 1 0 2 2 2 2 FCD domain Shigella_OspC PF06128.11 EER25546.1 - 0.13 11.9 0.3 20 4.8 0.0 3.0 3 0 0 3 3 3 0 Shigella flexneri OspC protein CorA PF01544.18 EER25547.1 - 4.6e-06 26.2 2.8 4.6e-06 26.2 2.8 2.4 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Fig1 PF12351.8 EER25548.1 - 2.6e-46 157.9 1.6 3.5e-46 157.5 1.6 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 MASE3 PF17159.4 EER25548.1 - 0.038 13.6 0.2 0.038 13.6 0.2 2.2 1 1 1 2 2 2 0 Membrane-associated sensor domain PGM_PMM_I PF02878.16 EER25549.1 - 8.8e-37 125.9 0.0 1.7e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EER25549.1 - 1.3e-25 90.0 0.1 2.5e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EER25549.1 - 8.1e-15 55.0 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EER25549.1 - 8.3e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FA_desaturase PF00487.24 EER25550.1 - 7.8e-26 91.4 30.1 1.3e-25 90.7 30.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EER25550.1 - 4.5e-11 42.7 0.0 9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CUE PF02845.16 EER25551.1 - 1.3e-07 31.1 0.0 2.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.22 EER25552.1 - 5.2e-27 93.9 0.3 6.1e-27 93.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ELYS PF13934.6 EER25554.1 - 2.5e-61 207.5 0.1 2.9e-61 207.2 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 EER25555.1 - 5.5e-79 264.7 0.0 5.6e-77 258.1 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EER25555.1 - 1e-22 80.6 0.0 4e-22 78.7 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EER25555.1 - 5.3e-12 46.2 0.7 4.5e-05 23.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Tropomyosin_1 PF12718.7 EER25555.1 - 7.7e-05 22.9 9.4 7.7e-05 22.9 9.4 7.3 2 2 4 7 7 7 1 Tropomyosin like AAA_29 PF13555.6 EER25555.1 - 0.00044 19.9 0.0 0.00087 19.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.9 EER25555.1 - 0.0015 18.5 8.1 0.0015 18.5 8.1 8.6 3 2 5 8 8 8 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.19 EER25555.1 - 0.0019 18.1 12.6 0.0019 18.1 12.6 6.7 3 2 5 8 8 8 1 Ezrin/radixin/moesin family Lebercilin PF15619.6 EER25555.1 - 0.0062 16.2 13.0 0.0062 16.2 13.0 6.2 4 3 2 6 6 6 2 Ciliary protein causing Leber congenital amaurosis disease BTB_2 PF02214.22 EER25555.1 - 0.11 12.9 0.1 0.36 11.2 0.1 1.9 1 0 0 1 1 1 0 BTB/POZ domain RT_RNaseH PF17917.1 EER25555.1 - 0.52 10.6 4.8 0.45 10.8 0.1 2.8 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Fungal_trans PF04082.18 EER25556.1 - 1e-15 57.5 0.1 1.7e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER25556.1 - 5.9e-08 32.7 7.6 1.2e-07 31.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.12 EER25557.1 - 1.4e-67 227.4 0.0 1.6e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Drc1-Sld2 PF11719.8 EER25558.1 - 1.5e-104 351.1 18.8 1.7e-104 350.9 18.8 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein zf-C3HC4_3 PF13920.6 EER25559.1 - 2.8e-08 33.5 2.8 4.6e-08 32.8 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER25559.1 - 3.4e-08 33.7 5.5 6.7e-08 32.7 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EER25559.1 - 1.4e-06 28.1 2.7 2.3e-06 27.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER25559.1 - 2.9e-06 27.0 4.6 4.9e-06 26.3 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EER25559.1 - 1.3e-05 25.4 5.6 2.7e-05 24.3 5.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EER25559.1 - 0.00022 21.0 3.3 0.00049 19.9 3.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EER25559.1 - 0.12 12.2 1.5 0.26 11.1 1.5 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_5 PF14634.6 EER25559.1 - 1.3 9.1 7.4 0.38 10.8 2.9 2.3 2 1 0 2 2 2 0 zinc-RING finger domain HAD_SAK_1 PF10307.9 EER25560.1 - 2.6e-77 259.2 0.0 3.5e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Fig1 PF12351.8 EER25561.1 - 1.6e-59 201.0 1.8 1.6e-59 201.0 1.8 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EER25561.1 - 0.00048 19.8 6.9 0.0013 18.4 6.9 1.7 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 EER25561.1 - 0.0013 17.8 3.8 0.0024 17.0 3.8 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 EER25561.1 - 4.8 5.8 13.2 1 8.0 0.5 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) XPG_I PF00867.18 EER25562.1 - 2.7e-24 85.3 0.1 5.4e-24 84.4 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EER25562.1 - 1.1e-20 74.0 0.0 3e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 EER25562.1 - 0.0004 19.9 0.0 0.00063 19.3 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EER25562.1 - 0.022 15.4 0.0 0.05 14.2 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DUF4106 PF13388.6 EER25562.1 - 0.27 10.4 1.7 0.51 9.5 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) OPT PF03169.15 EER25563.1 - 2.5e-157 525.2 51.5 6.6e-157 523.8 51.5 1.6 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF885 PF05960.11 EER25564.1 - 5.5e-47 161.6 0.0 7.7e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) PSCyt3 PF07627.11 EER25565.1 - 0.0059 16.9 0.3 0.031 14.5 0.3 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1588) zf-rbx1 PF12678.7 EER25565.1 - 0.0064 16.7 12.3 0.013 15.8 12.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EER25565.1 - 0.1 12.7 9.4 0.96 9.5 9.4 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tim17 PF02466.19 EER25568.1 - 5.5e-32 110.4 9.0 6.7e-32 110.2 9.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 EER25568.1 - 0.19 11.9 0.0 0.47 10.6 0.0 1.7 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal MAM33 PF02330.16 EER25569.1 - 1e-68 231.5 0.1 1.4e-68 231.1 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein DNA_primase_S PF01896.19 EER25570.1 - 1.2e-64 217.6 0.1 2e-64 216.9 0.1 1.4 1 0 0 1 1 1 1 DNA primase small subunit MFS_1 PF07690.16 EER25571.1 - 1.3e-36 126.3 50.6 1.3e-36 126.3 50.6 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily FixQ PF05545.11 EER25571.1 - 1.3 9.0 3.9 0.6 10.1 0.3 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DIOX_N PF14226.6 EER25572.1 - 1.8e-36 125.4 0.0 1.1e-33 116.4 0.0 2.4 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EER25572.1 - 2.3e-15 56.9 0.0 4.3e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GxGYxYP_C PF14323.6 EER25572.1 - 0.04 13.8 0.0 0.067 13.1 0.0 1.3 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain DUF3435 PF11917.8 EER25574.1 - 0.0043 16.1 0.0 0.007 15.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) RTC4 PF14474.6 EER25575.1 - 5.7e-21 74.9 0.0 6.4e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain DUF3050 PF11251.8 EER25575.1 - 0.005 16.5 0.0 0.0061 16.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3050) Pkinase PF00069.25 EER25576.1 - 0.02 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Sugar_tr PF00083.24 EER25578.1 - 2.5e-103 346.4 21.8 3e-103 346.1 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER25578.1 - 1.2e-21 77.1 32.4 2e-13 50.0 11.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_N PF01194.17 EER25580.1 - 1.4e-13 50.9 0.0 1.5e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 EER25581.1 - 1.1e-06 29.3 1.3 0.35 11.8 0.2 5.6 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EER25581.1 - 0.0014 17.8 0.1 0.0063 15.6 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.6 EER25581.1 - 0.02 14.5 0.0 14 5.1 0.0 3.5 5 0 0 5 5 5 0 PQQ-like domain Ribonuc_L-PSP PF01042.21 EER25582.1 - 1.6e-08 34.5 0.0 2.6e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Lactamase_B PF00753.27 EER25583.1 - 2e-19 70.4 2.7 2.7e-19 70.0 2.7 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EER25583.1 - 3.9e-05 23.3 1.0 6.6e-05 22.5 1.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PGM_PMM_I PF02878.16 EER25583.1 - 0.024 14.4 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Pyr_redox_2 PF07992.14 EER25584.1 - 4.5e-70 236.2 6.6 4.5e-70 236.2 6.6 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EER25584.1 - 5.3e-40 136.1 0.1 1.6e-39 134.6 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EER25584.1 - 2.1e-20 73.0 10.6 1.7e-19 70.1 1.3 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EER25584.1 - 1.5e-10 41.0 9.7 5.7e-10 39.1 0.2 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EER25584.1 - 7.4e-10 38.5 10.7 7.4e-08 31.9 4.3 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EER25584.1 - 2.9e-09 37.0 4.9 5.5e-05 23.3 0.5 3.0 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EER25584.1 - 4.7e-09 35.9 7.3 2.4e-07 30.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EER25584.1 - 2.9e-07 30.0 5.1 0.0034 16.7 0.5 3.6 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EER25584.1 - 2.9e-07 30.0 0.2 0.0032 16.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EER25584.1 - 7.3e-07 28.6 3.4 7.3e-07 28.6 3.4 3.1 3 1 0 3 3 3 1 FAD binding domain DAO PF01266.24 EER25584.1 - 4.4e-06 26.5 10.5 0.025 14.1 0.3 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.14 EER25584.1 - 7.1e-06 25.0 14.8 0.001 17.9 2.1 4.1 4 0 0 4 4 4 3 HI0933-like protein Thi4 PF01946.17 EER25584.1 - 9.6e-06 25.0 1.7 0.00014 21.2 0.1 2.4 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EER25584.1 - 2.2e-05 23.7 0.3 0.0049 16.0 0.0 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 EER25584.1 - 0.031 14.7 0.8 0.71 10.3 0.1 2.8 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 EER25584.1 - 0.12 10.7 1.7 0.72 8.2 0.1 2.5 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 EER25584.1 - 1.2 8.3 13.7 1 8.6 1.3 3.4 3 1 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.14 EER25584.1 - 1.6 7.5 7.0 1.2 7.9 0.7 2.2 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 EER25584.1 - 7.6 6.4 8.9 0.29 11.0 1.1 2.5 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain EI24 PF07264.11 EER25585.1 - 1.9e-14 54.3 4.6 1.1e-06 29.0 0.1 2.5 1 1 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.6 EER25585.1 - 0.061 13.6 0.1 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) eIF-3_zeta PF05091.12 EER25586.1 - 0.18 10.8 3.6 0.21 10.6 3.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Peptidase_S8 PF00082.22 EER25588.1 - 6.7e-37 127.3 12.4 1.4e-36 126.3 12.4 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER25588.1 - 1.2e-11 45.1 0.0 2.5e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1754 PF08555.10 EER25589.1 - 0.012 16.4 7.9 0.012 16.4 7.9 4.0 3 1 0 3 3 3 0 Eukaryotic family of unknown function (DUF1754) MDM10 PF12519.8 EER25589.1 - 5 5.9 7.4 8.8 5.1 7.4 1.4 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 PMC2NT PF08066.12 EER25590.1 - 0.033 14.9 0.0 1.2 9.9 0.0 2.3 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Pex19 PF04614.12 EER25590.1 - 0.23 11.2 8.0 0.69 9.6 4.0 2.1 1 1 0 2 2 2 0 Pex19 protein family DUF1308 PF07000.11 EER25590.1 - 0.28 11.1 1.3 0.31 11.0 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1308) Peroxin-3 PF04882.12 EER25590.1 - 1.9 7.4 8.4 0.053 12.5 0.8 1.8 1 1 1 2 2 2 0 Peroxin-3 Pex14_N PF04695.13 EER25591.1 - 0.093 13.4 9.9 0.11 13.1 9.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MGC-24 PF05283.11 EER25591.1 - 0.16 12.4 21.0 2.2 8.7 21.0 1.9 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3498 PF12004.8 EER25591.1 - 0.49 9.5 8.9 0.55 9.4 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) DGF-1_C PF11040.8 EER25591.1 - 3.9 7.5 7.6 11 6.0 7.6 1.8 1 1 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Dicty_REP PF05086.12 EER25591.1 - 6.2 4.7 9.4 6.5 4.6 9.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4366 PF14283.6 EER25591.1 - 6.8 6.7 7.2 39 4.3 7.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) MSA-2c PF12238.8 EER25591.1 - 7.3 6.5 26.7 2.6 8.0 16.4 2.0 1 1 1 2 2 2 0 Merozoite surface antigen 2c DUF2828 PF11443.8 EER25592.1 - 3.6e-204 679.5 4.9 6.6e-197 655.5 0.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) DUF2656 PF10847.8 EER25592.1 - 0.066 13.3 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) Speriolin_C PF15059.6 EER25592.1 - 0.15 12.2 0.2 0.42 10.7 0.2 1.7 1 0 0 1 1 1 0 Speriolin C-terminus FA_desaturase PF00487.24 EER25593.1 - 1.6e-26 93.7 28.0 2.4e-26 93.1 28.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EER25593.1 - 4e-10 39.7 0.0 1.9e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FSH1 PF03959.13 EER25594.1 - 8e-31 107.3 0.0 1e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EER25594.1 - 0.00078 19.3 0.0 0.0049 16.7 0.0 1.9 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase ketoacyl-synt PF00109.26 EER25595.1 - 2e-67 227.4 0.0 4.4e-67 226.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EER25595.1 - 1e-61 208.0 1.3 2.5e-61 206.7 1.3 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EER25595.1 - 4.8e-56 190.2 1.2 7.7e-56 189.5 0.6 1.6 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EER25595.1 - 4.3e-46 157.9 0.1 1.5e-45 156.1 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EER25595.1 - 3.4e-39 133.5 0.8 1.2e-38 131.8 0.2 2.4 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EER25595.1 - 1.2e-17 65.2 0.0 7.2e-16 59.5 0.0 3.2 3 0 0 3 3 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EER25595.1 - 6.3e-16 58.8 0.1 1.7e-15 57.5 0.1 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EER25595.1 - 6.4e-15 55.3 0.0 1.5e-13 50.9 0.0 3.1 3 0 0 3 3 3 1 Zinc-binding dehydrogenase adh_short PF00106.25 EER25595.1 - 1.8e-09 37.3 0.3 5e-09 35.9 0.3 1.7 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.25 EER25595.1 - 2.6e-06 27.7 0.8 8.6e-06 26.0 0.8 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EER25595.1 - 4.2e-05 24.2 0.0 0.00034 21.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain adh_short_C2 PF13561.6 EER25595.1 - 4.3e-05 23.2 0.2 0.00011 21.9 0.2 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.6 EER25595.1 - 0.00096 19.0 0.0 0.0039 17.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain YjeF_N PF03853.15 EER25595.1 - 0.00097 19.1 0.2 0.81 9.6 0.0 2.9 3 0 0 3 3 2 2 YjeF-related protein N-terminus PALP PF00291.25 EER25595.1 - 0.0014 18.1 0.4 0.016 14.7 0.1 2.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Shikimate_DH PF01488.20 EER25595.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EER25596.1 - 9.2e-21 74.5 0.3 4.4e-20 72.2 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EER25596.1 - 0.011 15.3 3.2 0.018 14.6 2.6 1.6 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EER25596.1 - 0.032 14.8 0.5 0.032 14.8 0.5 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EER25596.1 - 0.044 12.8 0.0 2.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DUF3382 PF11862.8 EER25596.1 - 0.088 13.1 0.1 0.21 11.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) Pyr_redox_2 PF07992.14 EER25596.1 - 0.16 11.2 0.0 1.1 8.4 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ketoacyl-synt PF00109.26 EER25597.1 - 3.9e-68 229.8 0.3 1.6e-67 227.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EER25597.1 - 3.9e-32 110.7 0.0 9.3e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EER25597.1 - 3.2e-26 92.0 0.0 8.2e-26 90.7 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Acyl_transf_1 PF00698.21 EER25597.1 - 1.2e-23 84.1 0.0 1.2e-23 84.1 0.0 2.4 4 0 0 4 4 4 1 Acyl transferase domain SAT PF16073.5 EER25597.1 - 5.4e-12 46.0 1.6 3e-07 30.4 0.0 3.1 3 1 0 3 3 3 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 EER25597.1 - 4.8e-11 42.9 0.8 4.8e-10 39.6 0.4 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.21 EER25597.1 - 2.1e-06 27.4 0.0 1e-05 25.1 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KAsynt_C_assoc PF16197.5 EER25597.1 - 3.3e-05 24.3 0.1 0.00014 22.2 0.0 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EER25597.1 - 8.6e-05 22.0 0.0 0.00023 20.6 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.19 EER25597.1 - 0.042 12.8 0.0 5.2 6.0 0.0 3.0 4 0 0 4 4 4 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EER25597.1 - 0.06 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 KR domain DapB_N PF01113.20 EER25597.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Amino_oxidase PF01593.24 EER25598.1 - 7.1e-51 173.9 0.0 9.9e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EER25598.1 - 1.5e-14 53.9 0.4 3.1e-14 53.0 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EER25598.1 - 3.6e-11 43.1 0.0 2.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.24 EER25598.1 - 4.2e-10 39.7 0.0 6e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EER25598.1 - 5.7e-08 32.3 0.2 9e-08 31.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EER25598.1 - 8.9e-08 31.7 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EER25598.1 - 2.8e-07 30.1 0.4 1.9e-05 24.1 0.2 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EER25598.1 - 1.3e-06 27.8 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EER25598.1 - 2.9e-06 26.3 0.0 3.8e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EER25598.1 - 9.4e-05 21.6 0.1 0.00015 21.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EER25598.1 - 0.00038 21.0 0.0 0.011 16.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER25598.1 - 0.00052 19.4 0.0 0.13 11.5 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EER25598.1 - 0.0049 16.2 0.0 0.017 14.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EER25598.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EER25598.1 - 0.029 14.4 0.1 0.45 10.5 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.8 EER25599.1 - 1.5e-06 27.3 0.1 2.1e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT PF02985.22 EER25599.1 - 0.11 12.9 0.4 6 7.4 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat SnoaL_2 PF12680.7 EER25600.1 - 9.4e-05 23.0 0.1 0.00018 22.1 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EER25600.1 - 0.00045 20.0 0.0 0.00085 19.1 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase F-box-like PF12937.7 EER25601.1 - 0.011 15.5 2.3 0.011 15.5 2.3 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 EER25601.1 - 0.22 11.4 1.5 0.62 10.0 0.9 2.1 2 0 0 2 2 2 0 F-box domain FmdA_AmdA PF03069.15 EER25602.1 - 7.4e-180 597.7 0.0 8.5e-180 597.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Pro_isomerase PF00160.21 EER25603.1 - 1.9e-48 164.7 0.4 3.3e-48 163.9 0.4 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EER25603.1 - 4e-07 29.6 5.3 2.6e-06 27.1 0.8 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER25603.1 - 1.2e-06 28.0 4.0 2.3e-06 27.1 0.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER25603.1 - 0.0032 17.1 8.8 0.012 15.3 0.7 3.4 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 EER25603.1 - 0.01 16.0 8.6 0.076 13.3 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EER25603.1 - 0.024 15.4 4.3 0.47 11.4 1.6 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat PRODH PF18327.1 EER25603.1 - 0.045 14.0 1.0 0.089 13.0 1.0 1.5 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain TPR_12 PF13424.6 EER25603.1 - 0.07 13.4 4.9 0.28 11.5 2.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EER25603.1 - 0.076 13.2 0.3 0.4 10.9 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EER25603.1 - 0.13 12.7 0.1 3.3 8.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EER25603.1 - 0.17 12.6 2.9 1.3 9.7 1.6 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EER25603.1 - 0.21 12.1 3.3 0.62 10.6 3.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.16 EER25604.1 - 2.2e-50 170.9 0.0 2.5e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 EER25605.1 - 6.2e-87 290.9 17.3 1.2e-86 289.9 17.3 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EER25605.1 - 1e-41 142.1 13.4 1e-41 142.1 13.4 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 EER25605.1 - 0.032 14.1 3.9 0.077 12.8 3.9 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 EER25605.1 - 0.75 10.2 8.0 0.17 12.2 2.9 2.5 2 0 0 2 2 2 0 Syntaxin-like protein Ank_4 PF13637.6 EER25606.1 - 1.5e-44 149.8 14.8 3.8e-08 33.7 0.1 10.1 3 1 7 10 10 10 9 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER25606.1 - 6.2e-41 138.9 10.6 7.7e-14 52.1 0.9 4.8 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER25606.1 - 5.9e-34 115.7 14.8 1.6e-09 37.9 0.2 6.6 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 EER25606.1 - 6.3e-32 108.6 23.6 5.5e-06 26.6 0.1 9.1 8 2 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EER25606.1 - 1.3e-31 105.1 13.6 0.00059 20.1 0.0 9.8 11 0 0 11 11 11 7 Ankyrin repeat F-box-like PF12937.7 EER25606.1 - 8.8e-05 22.3 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EER25606.1 - 0.0049 16.7 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 F-box Carb_anhydrase PF00194.21 EER25607.1 - 1.2e-28 100.3 0.0 2.3e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Nop14 PF04147.12 EER25607.1 - 0.033 12.4 19.9 0.042 12.1 19.9 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2020 PF09449.10 EER25607.1 - 0.044 13.6 0.6 0.072 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2020) SDA1 PF05285.12 EER25607.1 - 0.13 11.7 21.3 0.17 11.3 21.3 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EER25607.1 - 1.8 7.8 19.2 2.4 7.4 19.2 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EER25607.1 - 2 6.6 26.8 2.8 6.1 26.8 1.1 1 0 0 1 1 1 0 CDC45-like protein U79_P34 PF03064.16 EER25607.1 - 2 7.7 22.1 3.7 6.8 22.1 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PPP4R2 PF09184.11 EER25607.1 - 2.7 7.5 17.3 5.2 6.6 17.3 1.4 1 0 0 1 1 1 0 PPP4R2 DNA_binding_1 PF01035.20 EER25608.1 - 1.1e-23 83.1 0.6 1.6e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fox-1_C PF12414.8 EER25608.1 - 0.28 11.6 2.7 4.2 7.8 0.1 2.5 1 1 1 2 2 2 0 Calcitonin gene-related peptide regulator C terminal Sugar_tr PF00083.24 EER25609.1 - 1.1e-91 308.0 20.3 1.2e-91 307.8 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER25609.1 - 2.6e-21 76.0 46.2 2.3e-16 59.7 21.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 EER25609.1 - 0.61 10.0 6.6 3.1 7.7 6.6 2.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain OATP PF03137.20 EER25609.1 - 7.6 4.7 13.6 1.4 7.1 4.2 2.9 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Inp1 PF12634.7 EER25610.1 - 9.1e-37 126.1 0.0 1.6e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 SRP14 PF02290.15 EER25611.1 - 5.6e-26 90.7 0.1 8.8e-26 90.1 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Mucin PF01456.17 EER25611.1 - 0.42 10.6 13.8 0.61 10.1 13.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MIF4G PF02854.19 EER25612.1 - 3.8e-22 79.0 3.0 5.1e-22 78.6 0.2 2.4 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.17 EER25612.1 - 5.6e-20 71.4 0.0 5.6e-20 71.4 0.0 2.0 2 0 0 2 2 2 1 MA3 domain BET PF17035.5 EER25612.1 - 3.3 8.0 6.0 1.1 9.5 0.4 2.9 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation Hydrolase_like PF13242.6 EER25613.1 - 2.1e-06 27.7 0.0 5.7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 EER25613.1 - 0.021 14.9 0.1 0.084 13.0 0.0 2.0 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MRC1 PF09444.10 EER25615.1 - 1.4e-40 139.2 19.8 1.4e-40 139.2 19.8 5.8 4 1 1 5 5 5 1 MRC1-like domain SSP160 PF06933.11 EER25615.1 - 9.2 4.3 8.4 16 3.5 8.4 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Plus-3 PF03126.18 EER25616.1 - 1.7e-32 112.2 0.0 6.4e-32 110.3 0.0 2.0 2 0 0 2 2 2 1 Plus-3 domain COQ7 PF03232.13 EER25617.1 - 7.2e-68 227.7 0.0 8.9e-68 227.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EER25617.1 - 1.8e-05 25.1 0.0 0.00028 21.3 0.0 2.1 1 1 1 2 2 2 1 Rubrerythrin UPF0184 PF03670.13 EER25617.1 - 0.027 14.9 0.1 0.044 14.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) RAC_head PF16717.5 EER25617.1 - 0.12 13.4 0.1 0.27 12.3 0.1 1.5 1 0 0 1 1 1 0 Ribosome-associated complex head domain LMWPc PF01451.21 EER25618.1 - 1.6e-33 116.1 0.0 6.3e-33 114.1 0.0 1.8 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FAD_binding_4 PF01565.23 EER25620.1 - 1.7e-17 63.4 2.6 2.6e-17 62.9 2.6 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EER25620.1 - 1.3e-05 25.2 0.2 4.8e-05 23.4 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like Chitin_synth_1 PF01644.17 EER25621.1 - 1.7e-74 249.2 0.0 2.6e-74 248.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EER25621.1 - 1.7e-29 101.6 0.0 3.3e-29 100.6 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EER25621.1 - 1.3e-22 80.2 4.9 2.6e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EER25621.1 - 1.7e-05 24.8 11.0 1.7e-05 24.8 11.0 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 CAP59_mtransfer PF11735.8 EER25623.1 - 2.1e-86 289.5 0.0 2.7e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF3325 PF11804.8 EER25623.1 - 0.017 15.2 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) TMEM234 PF10639.9 EER25624.1 - 4.8e-34 116.9 2.2 3.4e-33 114.1 2.2 1.9 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 EER25624.1 - 3.1e-05 24.2 5.5 0.0098 16.1 3.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family HNH_2 PF13391.6 EER25625.1 - 1.8e-16 60.0 0.0 3.8e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease MFS_MOT1 PF16983.5 EER25626.1 - 1.7e-62 208.7 30.9 6.8e-32 110.2 7.1 3.3 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 EER25626.1 - 2.2e-06 26.7 13.7 2.8e-06 26.3 1.8 2.4 2 1 0 2 2 2 2 Sulfate permease family Pox_A14 PF05767.12 EER25626.1 - 6.5 7.0 8.1 4.6 7.5 0.4 3.7 2 2 1 3 3 3 0 Poxvirus virion envelope protein A14 PhyH PF05721.13 EER25627.1 - 2.2e-40 139.2 0.0 3.3e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UTP15_C PF09384.10 EER25628.1 - 2.2e-54 183.1 3.4 2.9e-54 182.7 0.9 2.1 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.32 EER25628.1 - 1.9e-18 66.5 1.8 0.00044 21.0 0.3 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25628.1 - 4.2e-09 36.6 0.1 0.0053 17.0 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EER25628.1 - 0.00031 20.4 1.1 0.00097 18.8 0.3 2.1 2 1 1 3 3 3 1 PQQ-like domain RAB3GAP2_N PF14655.6 EER25628.1 - 0.0025 17.1 0.2 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus CPSF_A PF03178.15 EER25628.1 - 0.027 13.8 0.0 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 CPSF A subunit region MoeA_N PF03453.17 EER25628.1 - 0.13 12.0 0.1 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 MoeA N-terminal region (domain I and II) C2 PF00168.30 EER25629.1 - 9.8e-15 54.7 0.0 1.7e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain AAA_12 PF13087.6 EER25630.1 - 1e-30 106.8 0.0 1.6e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EER25630.1 - 3.8e-21 76.1 0.5 3.3e-11 43.5 0.0 3.0 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.6 EER25630.1 - 2.9e-08 34.2 0.0 1.2e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EER25630.1 - 0.00023 21.0 0.0 0.0013 18.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EER25630.1 - 0.00028 20.5 0.0 0.0025 17.4 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 EER25630.1 - 0.012 15.3 0.1 0.22 11.2 0.0 2.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EER25630.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_L22 PF00237.19 EER25632.1 - 2.7e-26 91.8 0.1 1.5e-25 89.4 0.0 2.3 2 1 0 2 2 2 1 Ribosomal protein L22p/L17e RRM_1 PF00076.22 EER25633.1 - 1.6e-52 175.2 0.0 1.5e-16 60.0 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER25633.1 - 5e-37 125.6 0.0 6.7e-30 102.8 0.0 4.2 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EER25633.1 - 7.4e-08 32.3 0.0 0.14 12.1 0.0 4.1 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.11 EER25633.1 - 0.00048 19.5 1.0 0.0012 18.3 1.0 1.7 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM PF05172.13 EER25633.1 - 0.077 13.0 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.11 EER25633.1 - 0.092 12.8 0.1 5.7 7.0 0.0 3.3 4 0 0 4 4 4 0 RNA binding domain GARP PF16731.5 EER25633.1 - 0.39 10.4 16.6 0.12 12.1 11.0 2.2 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma TPR_14 PF13428.6 EER25633.1 - 0.93 10.5 6.6 1.1e+02 4.0 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4271 PF14093.6 EER25634.1 - 0.018 15.0 5.6 0.022 14.7 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) MFS_1 PF07690.16 EER25634.1 - 0.061 12.2 5.1 0.077 11.9 5.1 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2417 PF10329.9 EER25634.1 - 1.7 8.0 6.5 3.4 7.0 6.5 1.5 1 1 0 1 1 1 0 Region of unknown function (DUF2417) BTB PF00651.31 EER25635.1 - 4.1e-12 46.3 0.0 6.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 EER25636.1 - 2.9e-39 135.0 47.7 5.7e-39 134.0 42.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EER25636.1 - 0.079 12.7 10.1 2.2 8.1 5.6 2.6 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) His_Phos_1 PF00300.22 EER25637.1 - 1.2e-11 44.7 0.1 4.1e-11 42.9 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FAD_binding_4 PF01565.23 EER25638.1 - 1.4e-19 70.2 0.1 2.4e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EER25638.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like MARVEL PF01284.23 EER25641.1 - 6e-28 97.7 5.9 7.5e-28 97.4 5.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain Acyl_transf_3 PF01757.22 EER25641.1 - 0.037 13.1 9.0 0.047 12.7 2.9 2.1 2 0 0 2 2 2 0 Acyltransferase family Pkinase PF00069.25 EER25642.1 - 1.8e-72 243.9 0.0 2.5e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25642.1 - 1.3e-36 126.3 0.0 2.1e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EER25642.1 - 1.6e-17 64.0 0.0 1.3e-10 41.7 0.0 2.6 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EER25642.1 - 9.8e-15 54.4 0.0 2.2e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EER25642.1 - 7.4e-08 32.0 0.0 1.7e-06 27.6 0.0 2.3 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EER25642.1 - 0.00028 20.6 0.2 0.00057 19.5 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EER25642.1 - 0.017 14.1 0.1 0.026 13.5 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EER25642.1 - 0.048 13.6 0.1 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EER25642.1 - 0.05 13.0 0.1 0.099 12.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EER25642.1 - 0.06 12.2 0.1 0.089 11.6 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PRELI PF04707.14 EER25643.1 - 1.6e-25 89.7 0.0 9.4e-22 77.5 0.0 2.6 2 1 0 2 2 2 2 PRELI-like family TPR_1 PF00515.28 EER25644.1 - 1.2e-38 129.3 40.8 1.5e-06 27.8 0.2 11.6 10 1 1 11 11 11 11 Tetratricopeptide repeat TPR_2 PF07719.17 EER25644.1 - 5.3e-37 123.0 37.5 2.2e-05 24.2 0.2 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.6 EER25644.1 - 2.2e-24 85.8 24.7 4.4e-07 30.4 1.2 6.8 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EER25644.1 - 1e-23 82.7 24.0 1.3e-07 31.1 0.1 8.7 6 1 2 8 8 8 5 TPR repeat TPR_8 PF13181.6 EER25644.1 - 1.2e-22 78.1 27.1 0.00016 21.6 0.1 10.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 EER25644.1 - 1.5e-16 59.5 18.6 0.13 12.7 0.1 9.3 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EER25644.1 - 4e-14 52.7 36.0 0.00073 19.8 3.3 9.0 2 2 6 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 EER25644.1 - 1.3e-13 51.2 31.6 1.9e-05 25.1 1.9 7.0 4 1 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EER25644.1 - 9.3e-12 44.7 29.4 0.017 15.9 0.3 9.8 5 2 6 11 11 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 EER25644.1 - 1.9e-11 43.9 19.6 2.2e-06 27.7 0.3 6.4 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EER25644.1 - 8.4e-10 38.0 27.6 0.014 15.3 0.3 9.7 9 1 1 10 10 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EER25644.1 - 6.4e-08 32.7 22.0 0.042 14.1 0.6 5.9 3 2 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EER25644.1 - 4.3e-07 29.6 11.8 4.9e-06 26.2 8.8 3.0 1 1 1 2 2 2 1 MalT-like TPR region SHNi-TPR PF10516.9 EER25644.1 - 8.4e-07 28.4 8.9 0.005 16.3 0.1 6.5 6 0 0 6 6 6 1 SHNi-TPR TPR_10 PF13374.6 EER25644.1 - 1.7e-05 24.5 29.0 0.082 12.8 1.1 10.0 12 0 0 12 12 11 1 Tetratricopeptide repeat TAF1_subA PF14929.6 EER25644.1 - 0.0065 15.9 0.6 0.02 14.3 0.3 1.9 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A MAS20 PF02064.15 EER25644.1 - 0.013 15.6 1.7 0.013 15.6 1.7 4.3 4 1 1 5 5 5 0 MAS20 protein import receptor TPR_6 PF13174.6 EER25644.1 - 0.013 16.1 26.8 1.4 9.7 0.0 8.9 9 0 0 9 9 8 0 Tetratricopeptide repeat Hamartin PF04388.12 EER25644.1 - 0.026 13.2 1.5 0.031 13.0 1.5 1.2 1 0 0 1 1 1 0 Hamartin protein Sel1 PF08238.12 EER25644.1 - 0.026 15.2 7.9 0.92 10.3 0.1 4.6 4 0 0 4 4 3 0 Sel1 repeat GPCR_chapero_1 PF11904.8 EER25644.1 - 0.049 13.1 0.5 0.097 12.1 0.5 1.4 1 0 0 1 1 1 0 GPCR-chaperone Wzy_C_2 PF11846.8 EER25644.1 - 0.14 12.1 5.5 4.4 7.2 0.2 3.8 3 1 1 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal DUF1168 PF06658.12 EER25644.1 - 0.51 10.2 12.8 1.4 8.7 12.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) tRNA_anti-like PF12869.7 EER25644.1 - 0.76 9.4 4.0 0.46 10.1 0.8 2.1 2 0 0 2 2 2 0 tRNA_anti-like TPR_3 PF07720.12 EER25644.1 - 0.78 9.8 12.7 14 5.8 0.1 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat SPOUT_MTase PF02590.17 EER25644.1 - 0.93 9.5 4.9 1.5 8.8 0.1 3.0 3 0 0 3 3 2 0 Predicted SPOUT methyltransferase TPR_4 PF07721.14 EER25644.1 - 1.3 9.8 9.9 42 5.2 0.1 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat NARP1 PF12569.8 EER25644.1 - 2.9 6.7 35.1 0.14 11.0 7.1 4.5 1 1 2 4 4 4 0 NMDA receptor-regulated protein 1 Aminotran_4 PF01063.19 EER25645.1 - 1.8e-32 113.0 0.0 2.6e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV FHA PF00498.26 EER25647.1 - 2.3e-14 53.5 0.0 4.3e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Sec1 PF00995.23 EER25648.1 - 9.6e-127 424.6 0.0 1.1e-126 424.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF4692 PF15763.5 EER25649.1 - 0.049 14.1 0.2 0.16 12.4 0.2 1.9 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) T2SSE_N PF05157.15 EER25649.1 - 0.49 10.7 3.2 3.2 8.1 3.2 2.1 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain zf_CCCH_4 PF18345.1 EER25650.1 - 3.8e-06 26.8 4.6 6.7e-06 26.0 4.6 1.4 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EER25650.1 - 9.3e-05 23.1 1.0 0.00032 21.4 1.0 2.0 1 0 0 1 1 1 1 Torus domain zf-CCCH_4 PF18044.1 EER25650.1 - 0.00041 20.1 2.0 0.00066 19.4 2.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EER25650.1 - 0.0046 17.4 1.7 0.0076 16.7 1.7 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 EER25650.1 - 0.0061 16.4 0.7 0.01 15.7 0.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EER25650.1 - 0.0074 16.5 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger containing family GTP_EFTU PF00009.27 EER25651.1 - 2.9e-50 170.5 0.0 4.6e-50 169.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EER25651.1 - 3e-42 143.1 3.8 5e-42 142.4 3.8 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EER25651.1 - 4.3e-19 68.3 0.0 8e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EER25651.1 - 6e-08 33.0 0.2 1.6e-07 31.6 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 EER25651.1 - 7.9e-06 25.6 0.0 6.4e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 EER25651.1 - 4.1e-05 23.6 0.0 9.5e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EER25651.1 - 9e-05 22.5 0.0 0.00025 21.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EER25651.1 - 0.007 16.2 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EER25651.1 - 0.01 15.3 0.0 0.031 13.7 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EER25651.1 - 0.039 14.0 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Snurportin1 PF11538.8 EER25651.1 - 0.087 13.0 1.7 0.19 11.9 1.7 1.5 1 0 0 1 1 1 0 Snurportin1 Roc PF08477.13 EER25651.1 - 0.17 12.1 0.0 1.6 9.0 0.0 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HORMA PF02301.18 EER25652.1 - 3.5e-34 118.3 0.0 4.1e-34 118.0 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EER25652.1 - 0.0029 17.6 0.5 0.011 15.7 0.5 1.9 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF2660 PF10859.8 EER25652.1 - 0.042 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF3530 PF12048.8 EER25652.1 - 0.059 12.8 0.1 0.09 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) FlaG PF03646.15 EER25652.1 - 4.3 7.6 8.3 13 6.0 1.6 2.8 2 1 0 2 2 2 0 FlaG protein RNA_pol_Rpb1_1 PF04997.12 EER25653.1 - 1.5e-85 287.3 0.1 2.4e-85 286.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EER25653.1 - 5.2e-81 272.0 1.1 8e-81 271.4 1.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EER25653.1 - 3.5e-71 238.8 0.0 8.9e-71 237.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EER25653.1 - 4.6e-35 120.9 0.0 1.5e-34 119.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EER25653.1 - 1.4e-28 99.0 0.1 4.4e-28 97.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M10_C PF08548.11 EER25653.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal Opy2 PF09463.10 EER25655.1 - 1.4e-07 31.7 19.3 2.3e-07 31.0 19.3 1.4 1 0 0 1 1 1 1 Opy2 protein Phage_HK97_TLTM PF06120.11 EER25655.1 - 0.18 11.0 0.1 0.29 10.3 0.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein 2OG-FeII_Oxy_2 PF13532.6 EER25656.1 - 9.2e-26 91.2 0.0 1.6e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EER25656.1 - 4.1e-23 82.4 0.0 1.4e-22 80.8 0.0 1.9 2 0 0 2 2 2 1 Isochorismatase family IlvN PF07991.12 EER25657.1 - 1.2e-46 158.3 0.0 1.9e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EER25657.1 - 1e-39 136.1 0.0 1.6e-39 135.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 EER25657.1 - 0.038 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EER25657.1 - 0.086 13.4 0.1 0.38 11.4 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.25 EER25658.1 - 1.4e-66 224.9 0.4 1.9e-66 224.5 0.4 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rad51 PF08423.11 EER25659.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad51 TAF8_C PF10406.9 EER25660.1 - 4e-22 78.5 1.4 4e-22 78.5 1.4 2.7 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EER25660.1 - 1e-07 31.9 0.4 2.5e-07 30.6 0.0 1.9 3 0 0 3 3 3 1 Bromodomain associated TFIIF_beta_N PF17683.1 EER25660.1 - 0.5 11.1 3.2 1.2 9.8 3.1 1.7 1 1 0 1 1 1 0 TFIIF, beta subunit N-terminus COX6C PF02937.15 EER25661.1 - 0.036 14.2 0.0 0.041 14.0 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc DUF4233 PF14017.6 EER25661.1 - 0.083 13.2 0.1 0.085 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) UQ_con PF00179.26 EER25662.1 - 1.1e-37 128.8 0.0 1.3e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1 PF01644.17 EER25663.1 - 2e-68 229.5 0.0 2.9e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EER25663.1 - 1.3e-28 98.7 0.0 2.4e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EER25663.1 - 1.7e-23 83.0 0.1 3.2e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EER25663.1 - 1.3e-08 35.0 1.0 1.3e-08 35.0 1.0 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Psu PF07455.11 EER25663.1 - 0.13 11.9 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Phage polarity suppression protein (Psu) DUF2846 PF11008.8 EER25664.1 - 0.058 13.4 1.7 0.2 11.7 0.1 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF2846) Kringle PF00051.18 EER25664.1 - 0.071 13.4 2.0 0.1 12.9 0.4 2.0 2 0 0 2 2 2 0 Kringle domain PALP PF00291.25 EER25665.1 - 2.6e-65 220.8 0.1 3e-65 220.5 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GHMP_kinases_C PF08544.13 EER25665.1 - 0.11 12.9 0.0 6.8 7.1 0.0 2.7 2 0 0 2 2 2 0 GHMP kinases C terminal DUF87 PF01935.17 EER25666.1 - 0.00043 20.4 0.3 0.36 10.9 0.1 2.3 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 EER25666.1 - 0.0025 18.1 0.7 0.99 9.7 0.7 2.6 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EER25666.1 - 0.018 14.3 0.0 0.09 12.0 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EER25666.1 - 0.035 13.4 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.6 EER25666.1 - 0.046 13.4 0.9 3.8 7.1 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Zot PF05707.12 EER25666.1 - 0.047 13.3 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SUR7 PF06687.12 EER25667.1 - 1.1e-27 97.1 7.4 1.5e-27 96.6 7.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family SNARE PF05739.19 EER25668.1 - 2.9e-13 49.6 0.1 7.2e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 EER25668.1 - 1.5e-09 36.8 0.2 5e-09 35.2 0.2 2.0 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 EER25668.1 - 0.00082 19.6 5.3 0.026 14.8 0.3 3.5 4 0 0 4 4 4 1 Uncharacterized conserved protein Syntaxin PF00804.25 EER25668.1 - 0.00098 18.8 0.1 0.00098 18.8 0.1 3.2 2 1 1 3 3 3 1 Syntaxin DUF4988 PF16378.5 EER25668.1 - 0.0036 17.0 2.9 3.2 7.4 0.0 3.2 2 1 1 3 3 3 2 Domain of unknown function Syntaxin-18_N PF10496.9 EER25668.1 - 0.0038 17.5 3.6 0.014 15.6 0.8 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.12 EER25668.1 - 0.035 14.6 3.8 10 6.7 0.1 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 EER25668.1 - 1.1 7.2 3.6 1.4 6.8 0.0 2.2 2 1 0 2 2 2 0 Prominin MCPsignal PF00015.21 EER25668.1 - 4 7.2 9.2 0.18 11.6 0.7 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HNH_2 PF13391.6 EER25669.1 - 5e-15 55.4 0.0 2e-14 53.5 0.0 2.0 2 0 0 2 2 2 1 HNH endonuclease CAAD PF14159.6 EER25671.1 - 0.12 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DcuC PF03606.15 EER25671.1 - 0.27 9.7 1.1 0.27 9.7 1.1 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier AgrB PF04647.15 EER25671.1 - 0.31 10.3 2.5 0.32 10.3 2.5 1.0 1 0 0 1 1 1 0 Accessory gene regulator B Pkinase PF00069.25 EER25672.1 - 2.3e-23 82.9 0.0 7e-23 81.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25672.1 - 1.8e-10 40.6 0.0 2.7e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER25672.1 - 0.032 13.0 0.0 0.067 12.0 0.0 1.4 1 1 1 2 2 2 0 Fungal protein kinase RPA_C PF08784.11 EER25672.1 - 0.2 12.3 0.0 0.35 11.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein A C terminal RNase_H PF00075.24 EER25674.1 - 3.4e-22 79.2 0.2 4.3e-22 78.8 0.2 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EER25674.1 - 8.3e-08 32.1 0.1 0.00098 18.9 0.1 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like RCC1 PF00415.18 EER25681.1 - 3.8e-30 104.3 16.0 6.3e-07 29.9 0.1 7.3 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EER25681.1 - 1.7e-13 50.0 31.1 3.7e-06 26.6 2.9 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.13 EER25682.1 - 1.2e-51 175.5 0.9 4.6e-51 173.7 0.9 1.8 1 1 0 1 1 1 1 Rad9 Rad1 PF02144.16 EER25682.1 - 0.00012 21.2 1.8 0.0082 15.2 0.4 2.9 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 YabA PF06156.13 EER25683.1 - 1.5 9.5 7.0 3.7 8.3 0.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA PPR_2 PF13041.6 EER25684.1 - 2.4e-19 69.3 0.1 1.8e-11 44.0 0.0 3.5 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 EER25684.1 - 0.00014 21.9 0.0 0.53 10.4 0.0 2.9 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR PF01535.20 EER25684.1 - 0.0002 21.4 0.0 0.021 15.0 0.0 3.2 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 EER25684.1 - 0.0088 15.4 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP IL23 PF16649.5 EER25684.1 - 0.13 12.3 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Interleukin 23 subunit alpha DEAD PF00270.29 EER25685.1 - 1.2e-49 168.5 0.0 2.1e-48 164.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER25685.1 - 2.3e-30 105.2 0.0 7e-30 103.6 0.0 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER25685.1 - 0.00028 21.0 0.0 0.00082 19.4 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EER25685.1 - 0.021 13.6 0.0 1.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 EER25685.1 - 0.03 14.7 0.0 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5335 PF17269.2 EER25685.1 - 0.072 12.9 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) DUF2443 PF10398.9 EER25685.1 - 0.1 12.7 0.3 0.21 11.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_22 PF13401.6 EER25685.1 - 0.2 12.0 0.4 43 4.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain Phos_pyr_kin PF08543.12 EER25687.1 - 2.6e-81 272.6 0.7 3.4e-81 272.3 0.7 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EER25687.1 - 4e-44 150.9 0.4 3.3e-23 82.6 0.1 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family HK PF02110.15 EER25687.1 - 0.003 17.0 1.4 0.12 11.7 0.3 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family PfkB PF00294.24 EER25687.1 - 0.0038 16.6 0.1 0.025 13.9 0.1 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DNA_pol_B PF00136.21 EER25688.1 - 1.8e-118 396.2 2.5 2.4e-118 395.8 2.5 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EER25688.1 - 5.2e-70 235.0 0.8 1.1e-69 233.9 0.8 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EER25688.1 - 2.1e-41 142.2 0.0 8.4e-41 140.2 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EER25688.1 - 2.1e-25 88.6 8.9 2.1e-25 88.6 8.9 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EER25688.1 - 0.003 16.5 1.5 0.0046 15.9 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral Campylo_MOMP PF05538.11 EER25688.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Campylobacter major outer membrane protein Ribosomal_L30_N PF08079.12 EER25689.1 - 1.2e-27 96.0 13.3 1.2e-27 96.0 13.3 1.7 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EER25689.1 - 8.7e-18 64.0 2.8 2.1e-17 62.7 2.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e EAP30 PF04157.16 EER25690.1 - 7.6e-74 247.9 0.0 8.7e-74 247.8 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.7 EER25690.1 - 0.021 14.7 0.0 0.071 13.0 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.6 EER25690.1 - 0.093 13.2 0.1 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Winged helix DNA-binding domain eIF-3c_N PF05470.12 EER25691.1 - 1.5e-171 571.7 25.6 5.8e-136 454.2 2.3 3.0 1 1 2 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EER25691.1 - 2.5e-12 47.2 5.2 2.4e-11 44.1 0.1 3.6 3 1 1 4 4 4 1 PCI domain DUF2884 PF11101.8 EER25691.1 - 0.022 14.3 0.3 0.022 14.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Pkinase PF00069.25 EER25692.1 - 2.7e-50 171.2 0.1 1.6e-49 168.7 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25692.1 - 2.8e-23 82.6 0.0 5.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER25692.1 - 0.00037 20.5 0.1 0.00037 20.5 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EER25692.1 - 0.0019 17.8 0.3 0.0052 16.4 0.3 1.6 1 1 0 1 1 1 1 RIO1 family SNF2_N PF00176.23 EER25693.1 - 2.5e-65 220.5 0.0 7e-65 219.0 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER25693.1 - 2.6e-18 66.4 0.0 6.5e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER25693.1 - 2e-06 27.9 0.0 1.4e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIF_beta PF02270.15 EER25693.1 - 0.0023 18.0 0.0 0.0055 16.8 0.0 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain HDA2-3 PF11496.8 EER25693.1 - 0.033 13.4 0.4 0.11 11.7 0.4 1.9 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Mucin PF01456.17 EER25694.1 - 2.7 8.0 16.2 0.082 12.9 9.7 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Med27 PF11571.8 EER25695.1 - 1.2e-15 57.7 0.0 2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 ArsB PF02040.15 EER25696.1 - 1.6e-13 50.8 15.9 7.3e-08 32.2 6.1 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein Usp PF00582.26 EER25697.1 - 1.5e-20 74.1 0.0 2.9e-20 73.2 0.0 1.5 1 0 0 1 1 1 1 Universal stress protein family RNA_pol_3_Rpc31 PF11705.8 EER25698.1 - 0.0064 16.8 4.2 0.0064 16.8 4.2 2.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 BUD22 PF09073.10 EER25698.1 - 0.049 13.0 10.5 0.068 12.5 10.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EER25698.1 - 0.098 12.1 9.4 0.12 11.7 9.4 1.2 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.12 EER25698.1 - 5.4 5.5 10.4 7 5.1 10.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.25 EER25699.1 - 4.1e-61 206.6 0.0 5.9e-61 206.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25699.1 - 1.3e-26 93.5 0.0 2e-26 92.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EER25699.1 - 0.0038 16.6 0.1 0.0038 16.6 0.1 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EER25699.1 - 0.0039 16.5 0.0 0.0069 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EER25699.1 - 0.02 13.8 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EER25699.1 - 0.049 13.2 0.1 0.049 13.2 0.1 1.6 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 EER25699.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Spore_coat_CotO PF14153.6 EER25699.1 - 0.18 11.7 5.1 0.3 11.0 5.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO HMA PF00403.26 EER25700.1 - 2.2e-13 50.4 0.0 3.9e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EER25700.1 - 7e-08 32.7 0.0 1e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Chordopox_RPO7 PF05864.12 EER25700.1 - 0.048 13.9 0.2 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TPR_2 PF07719.17 EER25701.1 - 3.9e-14 51.5 4.3 6.1e-05 22.8 0.1 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EER25701.1 - 7.1e-14 50.9 6.5 1.5e-06 27.8 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EER25701.1 - 5.6e-07 29.8 0.1 0.00013 22.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EER25701.1 - 1.5e-06 28.0 2.4 0.002 18.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat PB1 PF00564.24 EER25701.1 - 2.9e-06 27.1 0.0 7.5e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 PB1 domain TPR_7 PF13176.6 EER25701.1 - 3.7e-05 23.4 0.4 0.00042 20.1 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EER25701.1 - 9.3e-05 22.8 0.0 9.9 7.0 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EER25701.1 - 0.0001 22.9 0.1 0.0038 17.8 0.0 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER25701.1 - 0.00011 21.8 4.1 0.0014 18.2 0.6 3.5 3 1 1 4 4 4 1 TPR repeat TPR_14 PF13428.6 EER25701.1 - 0.014 16.2 0.0 0.23 12.4 0.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EER25701.1 - 0.042 13.7 0.2 0.53 10.2 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EER25701.1 - 0.046 14.1 1.5 3.9 8.1 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Syntaxin-18_N PF10496.9 EER25702.1 - 4.1e-12 46.2 0.7 4.1e-12 46.2 0.7 3.3 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EER25702.1 - 0.00039 20.4 0.2 0.0098 15.9 0.0 2.8 2 0 0 2 2 2 1 SNARE domain BLOC1_2 PF10046.9 EER25702.1 - 0.15 12.4 8.9 0.74 10.2 3.2 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FAM177 PF14774.6 EER25702.1 - 0.19 12.1 1.5 0.26 11.6 0.2 1.9 2 0 0 2 2 2 0 FAM177 family Acyl_transf_3 PF01757.22 EER25703.1 - 4.5e-10 39.1 28.0 4.5e-10 39.1 28.0 1.4 1 1 0 1 1 1 1 Acyltransferase family IRK PF01007.20 EER25703.1 - 5.9 6.7 8.9 0.77 9.6 1.4 2.4 2 1 0 2 2 2 0 Inward rectifier potassium channel transmembrane domain Aminotran_1_2 PF00155.21 EER25704.1 - 2e-84 283.9 0.0 2.3e-84 283.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.6 EER25705.1 - 1.4e-13 51.0 4.5 2.3e-13 50.3 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EER25705.1 - 2.1e-10 40.2 1.4 3.8e-10 39.3 1.4 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EER25705.1 - 4.6e-09 36.0 4.9 7.6e-09 35.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER25705.1 - 6.6e-08 32.3 3.0 1.1e-07 31.6 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EER25705.1 - 2.3e-07 31.0 3.1 5e-07 29.9 3.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EER25705.1 - 1.2e-05 25.2 1.6 2.4e-05 24.2 1.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EER25705.1 - 4.2e-05 23.3 6.6 0.00057 19.7 7.3 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EER25705.1 - 0.00094 19.0 1.6 0.0016 18.2 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EER25705.1 - 0.0026 17.8 3.0 0.0049 16.9 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EER25705.1 - 0.0057 16.7 6.7 0.013 15.5 6.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EER25705.1 - 0.0088 15.8 4.2 0.015 15.0 4.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EER25705.1 - 0.08 13.1 5.1 0.15 12.3 5.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 EER25705.1 - 0.59 10.1 2.7 1.3 8.9 2.7 1.6 1 0 0 1 1 1 0 PHD-finger Rad50_zn_hook PF04423.14 EER25705.1 - 0.81 9.6 2.4 34 4.4 0.1 3.2 3 0 0 3 3 3 0 Rad50 zinc hook motif Metal_resist PF13801.6 EER25705.1 - 1.3 9.2 6.4 7.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Heavy-metal resistance Prok-RING_1 PF14446.6 EER25705.1 - 1.5 8.8 5.0 1.7 8.7 1.7 2.5 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 MS_channel PF00924.18 EER25706.1 - 1.2e-17 64.1 2.6 2.6e-17 63.0 2.6 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EER25706.1 - 0.0011 18.3 0.2 0.0026 17.2 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EER25706.1 - 0.023 14.6 0.0 0.065 13.2 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EER25706.1 - 0.065 13.7 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 EER25706.1 - 0.085 12.4 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 EF hand TANGO2 PF05742.12 EER25707.1 - 8e-74 248.9 0.0 9.1e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 BPL_N PF09825.9 EER25708.1 - 6.9e-150 499.3 0.0 8.6e-150 499.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EER25708.1 - 6.6e-25 87.5 0.0 1.2e-24 86.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EER25708.1 - 1.1e-05 25.2 0.0 3.5e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain CHCH PF06747.13 EER25709.1 - 4.3e-05 23.5 5.9 5.7e-05 23.1 5.9 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EER25709.1 - 0.0083 16.1 1.5 0.011 15.8 1.4 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EER25709.1 - 0.031 14.3 0.9 0.031 14.3 0.9 1.6 1 1 1 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Mgm101p PF06420.12 EER25710.1 - 2.5e-87 290.7 0.0 3.3e-87 290.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MFS_1 PF07690.16 EER25711.1 - 3.9e-13 49.1 49.5 1.2e-08 34.3 13.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER25711.1 - 0.00031 19.8 10.3 0.00031 19.8 10.3 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TB2_DP1_HVA22 PF03134.19 EER25712.1 - 7.3e-15 54.7 7.1 1.2e-14 54.0 7.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MIF4G PF02854.19 EER25713.1 - 4.7e-48 163.6 0.0 8.1e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EER25713.1 - 2.3e-23 82.1 3.3 6.2e-23 80.8 3.3 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 RRM_1 PF00076.22 EER25715.1 - 0.00046 19.9 0.0 0.00086 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2263 PF10021.9 EER25716.1 - 1.1e-18 68.1 0.0 3.7e-18 66.3 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Csm1_N PF18504.1 EER25716.1 - 0.067 13.5 3.6 0.14 12.5 3.6 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain Methyltransf_28 PF02636.17 EER25717.1 - 4e-84 282.3 0.0 5e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.20 EER25718.1 - 1.9e-11 44.4 0.0 2.4e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.20 EER25719.1 - 1.8e-06 27.6 5.5 3.5e-06 26.6 5.5 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 Mucin PF01456.17 EER25719.1 - 0.083 12.9 5.2 0.14 12.1 5.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PGI PF00342.19 EER25721.1 - 1.4e-242 805.6 1.2 1.6e-242 805.4 1.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase WSC PF01822.19 EER25723.1 - 1.1e-38 131.3 31.6 1.1e-19 70.3 11.9 2.5 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.23 EER25723.1 - 7.2e-24 84.7 0.1 1.5e-23 83.7 0.1 1.5 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.18 EER25723.1 - 0.0093 16.0 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Photosystem I psaG / psaK Glyco_trans_2_3 PF13632.6 EER25724.1 - 7e-54 182.7 1.0 7e-54 182.7 1.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EER25724.1 - 0.01 15.6 0.0 0.11 12.3 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferase family 2 PMP1_2 PF08114.11 EER25724.1 - 5.3 6.9 5.9 0.77 9.6 0.2 2.4 2 0 0 2 2 2 0 ATPase proteolipid family Glyco_hydro_16 PF00722.21 EER25726.1 - 3.4e-19 69.0 0.1 8.6e-19 67.7 0.1 1.7 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 WSC PF01822.19 EER25727.1 - 1e-49 166.6 41.7 3.4e-19 68.8 10.3 3.3 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.11 EER25727.1 - 4.7e-27 94.7 0.0 3.3e-26 92.0 0.0 2.2 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 EER25727.1 - 1.2e-21 76.8 0.0 2.6e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PWI PF01480.17 EER25729.1 - 9.9e-17 61.0 0.7 2.4e-16 59.8 0.7 1.7 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 EER25729.1 - 0.0012 18.6 0.0 0.0033 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2207 PF09972.9 EER25729.1 - 3.6 6.2 5.3 6 5.5 5.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PA26 PF04636.13 EER25729.1 - 6.7 5.5 9.6 12 4.7 8.9 1.7 1 1 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAD_binding_4 PF01565.23 EER25730.1 - 8.2e-23 80.7 3.3 1.4e-22 80.0 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain Fungal_trans_2 PF11951.8 EER25731.1 - 0.0024 16.8 0.8 0.0035 16.2 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TIM21 PF08294.11 EER25732.1 - 3.7e-40 137.2 0.0 4.6e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EER25732.1 - 4.2e-08 32.9 0.0 9e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.18 EER25733.1 - 3.3e-34 117.5 0.2 5.1e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.22 EER25734.1 - 2e-74 250.4 0.0 3e-74 249.8 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EER25734.1 - 2.4e-36 124.6 0.0 4.8e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 EER25735.1 - 2.6e-55 188.1 0.9 3.5e-55 187.7 0.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EER25735.1 - 3.7e-11 42.6 0.6 1.4e-10 40.8 0.6 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EER25735.1 - 1.3e-07 31.0 1.7 2.1e-07 30.3 1.7 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 EER25735.1 - 0.00016 21.0 0.3 0.00025 20.3 0.3 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 EER25735.1 - 0.0007 18.8 1.5 0.0013 17.9 1.5 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NanE PF04131.14 EER25735.1 - 0.093 11.9 0.3 0.22 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase eIF3g PF12353.8 EER25736.1 - 3e-45 153.7 1.5 4.4e-45 153.1 1.5 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EER25736.1 - 4e-15 55.4 0.0 6.3e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EER25736.1 - 0.026 14.9 0.2 0.053 13.9 0.2 1.4 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 ribosomal_L24 PF17136.4 EER25736.1 - 8.4 6.9 6.8 0.96 9.9 0.9 2.4 2 1 1 3 3 3 0 Ribosomal proteins 50S L24/mitochondrial 39S L24 NDT80_PhoG PF05224.12 EER25737.1 - 4.2e-40 138.0 0.0 6.1e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family CCDC144C PF14915.6 EER25739.1 - 0.11 11.5 0.3 0.25 10.4 0.0 1.6 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region APH PF01636.23 EER25740.1 - 9.4e-09 35.5 3.0 4.6e-08 33.3 0.2 2.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family AMP-binding PF00501.28 EER25741.1 - 8e-90 301.4 0.0 1.2e-89 300.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER25741.1 - 0.0025 18.8 0.0 0.0057 17.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNB PF00773.19 EER25742.1 - 2.5e-49 168.4 0.0 6.1e-36 124.4 0.0 2.3 2 0 0 2 2 2 2 RNB domain adh_short PF00106.25 EER25743.1 - 2.1e-31 108.9 0.0 2.8e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER25743.1 - 8.6e-23 81.1 0.0 1.2e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF294 PF03445.13 EER25743.1 - 0.0074 16.1 0.2 0.014 15.2 0.2 1.5 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 KR PF08659.10 EER25743.1 - 0.04 13.8 0.1 0.095 12.6 0.1 1.7 1 1 0 1 1 1 0 KR domain 2-Hacid_dh_C PF02826.19 EER25743.1 - 0.069 12.5 0.0 0.67 9.3 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EER25743.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 EER25743.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase CTNNBL PF08216.11 EER25745.1 - 4.1e-40 136.2 0.1 2.1e-39 133.9 0.0 2.4 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Mo25 PF08569.11 EER25745.1 - 7.9e-05 22.2 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Mo25-like V-ATPase_H_N PF03224.14 EER25745.1 - 0.0018 17.6 0.4 0.005 16.2 0.3 1.7 2 0 0 2 2 2 1 V-ATPase subunit H MMS19_C PF12460.8 EER25745.1 - 0.028 13.6 0.6 2 7.5 0.1 2.3 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal Arm PF00514.23 EER25745.1 - 0.033 14.2 0.2 9.1 6.5 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PHTB1_C PF14728.6 EER25745.1 - 0.044 12.9 0.3 0.074 12.1 0.3 1.3 1 0 0 1 1 1 0 PTHB1 C-terminus PMC2NT PF08066.12 EER25745.1 - 0.3 11.8 3.7 8.3 7.2 0.1 3.4 2 1 0 3 3 3 0 PMC2NT (NUC016) domain RNA_pol_Rpb2_6 PF00562.28 EER25746.1 - 5.5e-124 414.2 0.1 7.7e-124 413.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EER25746.1 - 9.8e-60 201.5 0.0 2e-59 200.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EER25746.1 - 1.9e-47 161.3 0.0 3.3e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EER25746.1 - 7.4e-34 116.0 0.0 1.5e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EER25746.1 - 4.4e-26 90.8 0.1 1.1e-25 89.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EER25746.1 - 1.2e-24 86.4 0.3 2.9e-24 85.1 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EER25746.1 - 7.1e-23 80.9 0.3 2.3e-22 79.3 0.3 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 EER25746.1 - 0.16 12.7 0.2 0.41 11.4 0.2 1.6 1 0 0 1 1 1 0 MRN-interacting protein AMPK1_CBM PF16561.5 EER25747.1 - 0.0038 17.4 0.0 0.0078 16.4 0.0 1.5 1 1 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF3694 PF12473.8 EER25747.1 - 0.042 14.5 0.1 0.08 13.6 0.1 1.4 1 1 0 1 1 1 0 Kinesin protein ADH_N PF08240.12 EER25748.1 - 5.8e-23 80.9 0.9 8.8e-23 80.3 0.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER25748.1 - 1.2e-20 73.8 0.0 1.8e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER25748.1 - 5.5e-07 30.7 0.0 8.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EER25748.1 - 0.0038 16.6 0.1 0.006 16.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Nucleopor_Nup85 PF07575.13 EER25750.1 - 9.8e-19 67.3 0.2 2.9e-13 49.3 0.0 2.6 3 0 0 3 3 3 2 Nup85 Nucleoporin ADIP PF11559.8 EER25751.1 - 3e-39 134.6 10.2 3e-39 134.6 10.2 1.9 3 0 0 3 3 2 1 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EER25751.1 - 0.0002 21.0 10.8 0.0002 21.0 10.8 1.7 2 0 0 2 2 2 1 Golgin subfamily A member 5 Hom_end_hint PF05203.16 EER25751.1 - 0.0079 16.2 1.6 0.013 15.4 1.6 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint Nup88 PF10168.9 EER25751.1 - 0.011 13.6 4.8 0.02 12.7 4.8 1.4 1 0 0 1 1 1 0 Nuclear pore component LemA PF04011.12 EER25751.1 - 0.012 15.5 4.3 0.012 15.5 3.1 1.6 2 0 0 2 2 2 0 LemA family BicD PF09730.9 EER25751.1 - 0.019 13.4 7.9 0.014 13.8 5.4 1.7 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D RepA_C PF04796.12 EER25751.1 - 0.053 13.5 0.3 0.12 12.4 0.3 1.6 1 0 0 1 1 1 0 Plasmid encoded RepA protein FUSC PF04632.12 EER25751.1 - 0.073 11.6 2.8 0.13 10.8 2.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 EER25751.1 - 0.14 12.2 8.1 0.046 13.7 4.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NOG1_N PF17835.1 EER25751.1 - 0.55 10.2 6.1 1.1e+02 2.7 7.9 3.0 2 1 0 2 2 2 0 NOG1 N-terminal helical domain AKNA PF12443.8 EER25751.1 - 0.71 10.6 4.8 1.2 9.8 1.5 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor Spc7 PF08317.11 EER25751.1 - 0.83 8.5 12.7 0.43 9.4 10.3 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EER25751.1 - 1.1 9.5 13.2 3.6 7.8 0.9 3.2 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MADF_DNA_bdg PF10545.9 EER25751.1 - 1.2 9.5 3.5 2.9 8.3 1.1 2.7 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like TTRAP PF14203.6 EER25751.1 - 1.2 9.1 4.9 0.43 10.6 0.2 2.6 3 1 0 3 3 2 0 Putative tranposon-transfer assisting protein DUF641 PF04859.12 EER25751.1 - 1.2 9.4 12.9 5.5 7.3 3.5 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF724 PF05266.14 EER25751.1 - 1.4 8.7 7.4 1.4 8.7 5.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF4618 PF15397.6 EER25751.1 - 2.5 7.5 15.5 0.33 10.3 9.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Csm1_N PF18504.1 EER25751.1 - 2.9 8.3 16.9 5.6 7.4 0.9 4.7 3 1 2 5 5 5 0 Csm1 N-terminal domain HAUS-augmin3 PF14932.6 EER25751.1 - 3.2 7.3 8.9 14 5.1 7.2 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DUF3552 PF12072.8 EER25751.1 - 3.7 6.9 16.6 0.93 8.9 5.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 EER25751.1 - 5.2 6.3 9.7 13 5.0 9.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 EER25751.1 - 5.5 7.1 16.7 1.5 8.9 1.4 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus PRKG1_interact PF15898.5 EER25751.1 - 6.4 7.7 17.6 0.97 10.4 4.2 3.4 2 1 1 3 3 2 0 cGMP-dependent protein kinase interacting domain Rx_N PF18052.1 EER25751.1 - 7.6 6.9 6.7 5.4 7.4 0.7 3.2 3 1 0 3 3 3 0 Rx N-terminal domain TMPIT PF07851.13 EER25751.1 - 8.5 5.5 5.9 20 4.3 6.0 1.6 1 1 0 1 1 1 0 TMPIT-like protein LRR_4 PF12799.7 EER25752.1 - 0.00011 22.5 13.7 0.006 17.0 0.2 6.3 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) F-box PF00646.33 EER25752.1 - 0.0014 18.5 1.3 0.004 17.0 0.1 2.5 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 EER25752.1 - 0.047 14.2 8.8 48 5.1 0.1 6.8 8 1 0 8 8 8 0 Leucine Rich Repeat GP63 PF17471.2 EER25752.1 - 0.14 12.4 0.3 14 6.0 0.1 3.0 3 0 0 3 3 3 0 Gene product 63 LRR_8 PF13855.6 EER25752.1 - 0.41 10.5 8.9 0.45 10.3 0.1 4.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_2 PF07723.13 EER25752.1 - 6.5 7.6 8.1 14 6.5 0.4 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat IDO PF01231.18 EER25753.1 - 1.4e-35 122.9 0.0 2e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CLTH PF10607.9 EER25754.1 - 4.7e-34 117.4 0.0 7.9e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EER25754.1 - 7.4e-24 84.2 0.5 1.2e-23 83.4 0.5 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EER25754.1 - 0.00058 19.7 0.4 0.0016 18.4 0.1 2.0 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.11 EER25755.1 - 2.3e-66 224.2 27.9 2.8e-66 223.9 27.9 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 GDPD PF03009.17 EER25756.1 - 8.8e-47 160.0 0.0 1.3e-46 159.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EER25756.1 - 2.3e-25 89.0 2.3 6.5e-08 33.1 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EER25756.1 - 3.4e-14 51.5 2.5 0.017 15.6 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 EER25756.1 - 1.2e-13 51.3 6.0 5.5e-06 26.8 0.1 4.1 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EER25756.1 - 1.2e-13 51.0 1.5 8.7e-05 22.7 0.0 4.6 3 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EER25756.1 - 4.8e-12 45.7 4.2 0.011 16.1 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat SPX PF03105.19 EER25756.1 - 0.0023 17.9 0.0 0.033 14.1 0.1 2.2 2 0 0 2 2 2 1 SPX domain Ank_2 PF12796.7 EER25757.1 - 2.7e-24 85.5 0.0 1.8e-10 41.2 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER25757.1 - 3.2e-20 72.2 0.0 0.00029 21.3 0.0 5.7 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EER25757.1 - 3.9e-18 65.0 0.2 0.00019 21.7 0.0 6.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EER25757.1 - 6e-17 61.5 1.1 2.5e-06 27.6 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER25757.1 - 1.1e-15 56.1 0.3 0.09 13.4 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeat Helo_like_N PF17111.5 EER25757.1 - 2.8e-05 23.6 5.6 0.00014 21.3 5.6 2.2 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 EER25757.1 - 0.56 10.4 3.4 1.7 8.8 0.4 2.4 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Methyltransf_31 PF13847.6 EER25758.1 - 1.7e-29 102.6 0.0 2.5e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER25758.1 - 8.9e-21 74.4 0.1 1.8e-20 73.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER25758.1 - 8.7e-19 68.0 0.1 1.9e-18 66.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER25758.1 - 8.4e-16 58.0 0.1 1.5e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EER25758.1 - 4.9e-11 42.7 0.0 6.8e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EER25758.1 - 2.2e-10 40.6 0.0 3.4e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EER25758.1 - 9.3e-10 39.1 0.0 1.7e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EER25758.1 - 1.4e-09 37.8 0.0 2.1e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EER25758.1 - 5.5e-07 29.1 0.0 9.3e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EER25758.1 - 1.2e-06 28.2 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EER25758.1 - 3.2e-06 27.2 0.0 9.3e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 EER25758.1 - 0.00026 20.3 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain UPF0020 PF01170.18 EER25758.1 - 0.00035 20.3 0.0 0.00063 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.13 EER25758.1 - 0.0011 18.6 1.3 0.0036 16.9 0.3 2.1 2 1 0 2 2 2 1 Histone methylation protein DOT1 FtsJ PF01728.19 EER25758.1 - 0.0034 17.5 0.1 0.0063 16.6 0.1 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase GidB PF02527.15 EER25758.1 - 0.0072 15.7 0.1 0.014 14.7 0.1 1.4 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G ADH_zinc_N PF00107.26 EER25758.1 - 0.014 15.3 0.2 0.049 13.6 0.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_18 PF12847.7 EER25758.1 - 0.019 14.9 0.1 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EER25758.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.17 EER25758.1 - 0.037 13.2 0.1 0.083 12.1 0.1 1.5 1 1 0 1 1 1 0 O-methyltransferase CheR PF01739.18 EER25758.1 - 0.038 13.5 0.1 1.6 8.1 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DnaJ PF00226.31 EER25759.1 - 9.4e-14 51.3 0.0 2.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain RPA43_OB PF17875.1 EER25760.1 - 6.4e-39 133.4 0.0 6.4e-39 133.4 0.0 2.6 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EER25760.1 - 0.0079 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pyr_redox_2 PF07992.14 EER25761.1 - 3.5e-51 174.2 0.1 4.5e-51 173.8 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER25761.1 - 1.4e-16 60.8 0.3 4e-14 52.9 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EER25761.1 - 2.3e-16 59.5 0.0 4.2e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EER25761.1 - 5.5e-05 23.1 0.0 0.00018 21.4 0.0 1.9 2 0 0 2 2 1 1 Rieske-like [2Fe-2S] domain Reductase_C PF14759.6 EER25761.1 - 7.3e-05 23.2 0.0 0.00033 21.2 0.0 2.0 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.6 EER25761.1 - 0.00031 20.8 0.0 0.52 10.3 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF1188 PF06690.11 EER25761.1 - 0.00061 19.4 0.1 0.00092 18.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) FIST PF08495.10 EER25761.1 - 0.0084 16.1 0.1 0.033 14.2 0.0 1.9 2 0 0 2 2 2 1 FIST N domain K_oxygenase PF13434.6 EER25761.1 - 0.0085 15.3 0.0 0.96 8.5 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EER25761.1 - 0.017 15.4 0.3 2.9 8.2 0.1 2.5 2 0 0 2 2 2 0 TrkA-N domain Amino_oxidase PF01593.24 EER25761.1 - 0.028 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EER25761.1 - 0.046 12.4 0.0 7.9 5.1 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein CusF_Ec PF11604.8 EER25761.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Trp_halogenase PF04820.14 EER25761.1 - 0.068 12.0 0.0 8.3 5.1 0.0 2.5 2 1 1 3 3 3 0 Tryptophan halogenase Acetyltransf_14 PF03421.16 EER25761.1 - 0.25 11.4 0.1 0.57 10.2 0.1 1.5 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase Macoilin PF09726.9 EER25762.1 - 1.3 7.5 9.8 2.3 6.7 9.8 1.4 1 0 0 1 1 1 0 Macoilin family Arrestin_N PF00339.29 EER25763.1 - 6.2e-13 49.0 0.1 4.5e-08 33.3 0.0 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EER25763.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus Rgp1 PF08737.10 EER25763.1 - 0.19 10.9 0.0 0.41 9.8 0.0 1.5 1 0 0 1 1 1 0 Rgp1 V-ATPase_G PF03179.15 EER25764.1 - 6.4e-34 116.7 16.3 7.3e-34 116.5 16.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EER25764.1 - 0.011 15.8 12.1 0.011 15.8 12.1 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 EER25764.1 - 0.016 15.6 15.9 0.024 15.0 15.9 1.3 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF1834 PF08873.11 EER25764.1 - 0.037 13.8 0.8 0.047 13.4 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DUF3552 PF12072.8 EER25764.1 - 0.14 11.5 19.8 0.81 9.1 19.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) OmpH PF03938.14 EER25764.1 - 0.2 12.0 13.1 0.24 11.7 13.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ECM11 PF15463.6 EER25764.1 - 0.68 10.5 10.1 1.7 9.3 10.1 1.6 1 1 1 2 2 2 0 Extracellular mutant protein 11 ATP11 PF06644.11 EER25764.1 - 1.6 8.5 9.0 1.9 8.2 9.0 1.1 1 0 0 1 1 1 0 ATP11 protein DivIVA PF05103.13 EER25764.1 - 6.6 6.8 17.0 0.68 10.0 9.6 2.0 1 1 1 2 2 2 0 DivIVA protein PET117 PF15786.5 EER25765.1 - 1.1e-24 86.5 0.6 1.2e-24 86.3 0.6 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Fez1 PF06818.15 EER25766.1 - 0.077 13.4 23.2 0.067 13.6 20.4 2.0 2 0 0 2 2 2 0 Fez1 CALCOCO1 PF07888.11 EER25766.1 - 2.4 6.9 33.0 0.031 13.1 15.1 2.7 1 1 1 3 3 3 0 Calcium binding and coiled-coil domain (CALCOCO1) like Methyltransf_16 PF10294.9 EER25767.1 - 4.7e-13 49.2 0.0 7.2e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_25 PF13649.6 EER25767.1 - 0.00023 21.8 0.0 0.0012 19.5 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER25767.1 - 0.0017 19.1 0.0 0.0038 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER25767.1 - 0.005 16.7 0.0 0.013 15.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER25767.1 - 0.0052 16.3 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EER25767.1 - 0.012 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EER25767.1 - 0.045 13.8 0.0 0.075 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 EER25767.1 - 0.13 12.9 0.0 0.34 11.6 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 EER25767.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ribosomal_S24e PF01282.19 EER25768.1 - 1e-34 118.3 0.1 1.9e-34 117.4 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 EER25768.1 - 0.014 15.3 3.2 0.016 15.0 3.1 1.2 1 1 0 1 1 1 0 RRXRR protein Pro_isomerase PF00160.21 EER25769.1 - 1.7e-37 129.1 0.0 2.4e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EER25769.1 - 7.1e-16 57.8 0.0 1.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ESX-1_EspG PF14011.6 EER25769.1 - 0.018 14.7 0.1 0.033 13.8 0.1 1.5 1 0 0 1 1 1 0 EspG family UDPGP PF01704.18 EER25770.1 - 6.5e-57 193.0 0.0 8.7e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EER25770.1 - 0.014 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fer4_20 PF14691.6 EER25770.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster zf-CCHC PF00098.23 EER25771.1 - 2.3e-40 134.9 61.4 2.2e-07 30.6 0.9 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EER25771.1 - 3.6e-08 33.0 43.9 0.17 11.6 1.1 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 EER25771.1 - 0.00047 19.8 43.8 0.017 14.8 0.7 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EER25771.1 - 0.0043 17.0 49.0 0.017 15.1 1.0 6.9 3 2 3 6 6 6 4 Zinc knuckle Rad51 PF08423.11 EER25772.1 - 1.6e-99 332.3 0.0 2.1e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EER25772.1 - 2.3e-06 27.3 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EER25772.1 - 0.00013 21.7 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EER25772.1 - 0.053 14.1 0.4 0.22 12.2 0.1 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain AAA_24 PF13479.6 EER25772.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain RRM_Rrp7 PF17799.1 EER25773.1 - 5.3e-50 169.4 0.0 8.4e-50 168.7 0.0 1.3 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 EER25773.1 - 9.7e-29 99.9 9.0 9.7e-29 99.9 9.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain TFB6 PF17110.5 EER25774.1 - 4.7e-58 195.7 0.0 5.7e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH RRM_1 PF00076.22 EER25775.1 - 1e-45 153.4 0.0 7.4e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EER25775.1 - 1.3e-05 25.1 0.1 0.0015 18.5 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EER25775.1 - 0.0002 21.4 0.0 0.0012 18.9 0.0 2.1 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 EER25775.1 - 0.001 18.9 0.0 0.056 13.3 0.0 2.7 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EER25775.1 - 0.001 19.1 0.3 0.05 13.7 0.0 2.7 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 EER25775.1 - 0.0079 15.8 0.0 0.048 13.3 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EER25775.1 - 0.087 13.1 0.1 8.8 6.5 0.0 3.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter UPF0154 PF03672.13 EER25775.1 - 0.24 11.4 1.1 0.78 9.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) LisH PF08513.11 EER25779.1 - 7.9e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 LisH TRAPP PF04051.16 EER25780.1 - 8.9e-34 116.3 0.1 1.1e-32 112.8 0.0 1.9 1 1 1 2 2 2 2 Transport protein particle (TRAPP) component PNGaseA PF12222.8 EER25780.1 - 0.0042 16.0 0.0 0.0058 15.5 0.0 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A WD40 PF00400.32 EER25781.1 - 9.7e-37 124.3 12.9 8.1e-05 23.3 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25781.1 - 4.4e-12 46.1 0.2 0.0026 18.0 0.0 4.4 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EER25781.1 - 0.0062 15.9 0.0 20 4.3 0.1 3.5 2 1 2 4 4 4 2 WD40-like domain Nucleoporin_N PF08801.11 EER25781.1 - 0.041 12.6 0.8 7.2 5.2 0.0 3.1 3 1 0 3 3 3 0 Nup133 N terminal like Glyco_hydro_47 PF01532.20 EER25783.1 - 3.7e-111 372.2 0.0 3.8e-109 365.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 PAN_1 PF00024.26 EER25784.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 EER25784.1 - 0.005 16.3 1.3 0.011 15.2 0.1 2.1 2 1 0 2 2 2 1 Fringe-like Pribosyltran PF00156.27 EER25785.1 - 5.4e-17 61.8 0.0 7.6e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EER25785.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Tmemb_161AB PF10268.9 EER25786.1 - 0.015 13.9 0.0 0.02 13.6 0.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Cu-oxidase_2 PF07731.14 EER25787.1 - 4.6e-11 42.6 0.0 0.0016 18.1 0.0 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EER25787.1 - 1.4e-09 38.0 0.1 6.4e-08 32.6 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase Cupredoxin_1 PF13473.6 EER25787.1 - 0.0029 17.7 0.0 0.43 10.7 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain DUF824 PF05688.11 EER25787.1 - 0.07 13.0 0.1 0.23 11.3 0.0 1.9 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) Ribonuc_L-PSP PF01042.21 EER25789.1 - 2.4e-41 140.5 0.1 2.7e-41 140.4 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Membr_traf_MHD PF10540.9 EER25790.1 - 9.6e-19 68.0 0.2 1.3e-08 35.1 0.2 3.2 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EER25790.1 - 4.9e-14 52.5 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EER25790.1 - 8.7e-10 37.8 1.8 3.5e-08 32.5 0.8 2.3 2 0 0 2 2 2 2 Plant family of unknown function (DUF810) Big_10 PF17964.1 EER25790.1 - 0.067 13.2 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial Ig domain NDUF_B8 PF05821.11 EER25791.1 - 4.3e-09 36.5 0.1 5.2e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.23 EER25792.1 - 2.3e-64 217.3 1.0 5.1e-64 216.2 1.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER25792.1 - 2.1e-19 69.9 0.0 9.4e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER25792.1 - 4.7e-09 36.5 0.0 1.4e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 EER25792.1 - 1.6e-08 34.7 12.8 3.5e-08 33.7 10.8 2.6 2 0 0 2 2 2 1 HSA DEAD PF00270.29 EER25792.1 - 5.5e-05 23.0 0.0 0.00022 21.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Clr5 PF14420.6 EER25793.1 - 1.4e-13 50.9 0.8 7.3e-13 48.5 0.5 2.1 2 0 0 2 2 2 1 Clr5 domain ADH_zinc_N PF00107.26 EER25794.1 - 1.8e-28 99.1 0.6 2.9e-28 98.4 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER25794.1 - 3.4e-09 37.9 0.0 6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER25794.1 - 2e-06 27.6 0.0 1.2e-05 25.2 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EER25794.1 - 0.0072 15.8 0.3 0.023 14.2 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.18 EER25794.1 - 0.054 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pep_deformylase PF01327.21 EER25794.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase GRP PF07172.11 EER25795.1 - 0.013 16.2 28.1 0.013 16.2 28.1 2.4 1 1 1 2 2 2 0 Glycine rich protein family zf-Mss51 PF13824.6 EER25796.1 - 1.8e-27 95.2 10.0 5.6e-27 93.6 8.2 2.3 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EER25796.1 - 0.1 12.7 5.8 0.051 13.7 2.1 2.1 2 0 0 2 2 2 0 MYND finger Elf1 PF05129.13 EER25796.1 - 0.38 10.8 2.0 9.9 6.3 0.3 2.7 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Oxysterol_BP PF01237.18 EER25797.1 - 4.8e-137 456.8 0.0 1.8e-136 454.9 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 EER25797.1 - 1.4e-19 69.9 0.3 5.1e-14 52.1 0.1 3.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER25797.1 - 6.3e-19 68.4 0.1 1.7e-09 38.1 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EER25797.1 - 4.4e-15 55.4 0.1 1.2e-05 25.5 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EER25797.1 - 5e-12 44.9 0.1 0.00034 20.8 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat PH PF00169.29 EER25797.1 - 2.1e-11 44.3 0.2 4.6e-11 43.2 0.2 1.6 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EER25797.1 - 3.6e-09 37.0 0.0 3.8e-07 30.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) PH_8 PF15409.6 EER25797.1 - 1.5e-06 28.4 1.2 3.7e-06 27.1 0.5 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EER25797.1 - 9.3e-05 22.8 1.4 9.3e-05 22.8 1.4 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain LLC1 PF14945.6 EER25797.1 - 0.0012 19.4 0.7 0.0012 19.4 0.7 2.0 2 0 0 2 2 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF2384 PF09722.10 EER25797.1 - 0.034 14.2 0.2 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) Shigella_OspC PF06128.11 EER25797.1 - 0.12 12.1 0.0 6.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Shigella flexneri OspC protein RAP1 PF07218.11 EER25797.1 - 4 5.6 5.6 8.7 4.5 5.6 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ATP12 PF07542.11 EER25798.1 - 2e-44 150.8 0.1 3.2e-44 150.1 0.1 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_tranf_2_3 PF13641.6 EER25799.1 - 4.9e-30 105.1 0.1 6.6e-30 104.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EER25799.1 - 3.3e-08 33.5 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EER25799.1 - 6.4e-06 25.7 0.1 0.004 16.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 FMO-like PF00743.19 EER25801.1 - 1.5e-18 66.6 0.0 3.3e-17 62.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EER25801.1 - 4.7e-15 55.6 0.3 9.9e-14 51.3 0.2 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER25801.1 - 2.5e-12 46.6 0.1 3e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EER25801.1 - 8.2e-12 44.9 0.0 3.5e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER25801.1 - 2.5e-07 30.2 0.8 1e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EER25801.1 - 1.4e-06 28.4 1.5 1.3e-05 25.3 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER25801.1 - 2.9e-05 23.8 3.5 0.0091 15.6 0.8 3.7 4 1 0 4 4 4 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EER25801.1 - 0.0031 16.8 0.8 0.47 9.7 0.3 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 EER25801.1 - 0.0052 16.8 1.7 0.17 11.9 1.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EER25801.1 - 0.01 15.2 4.1 0.25 10.6 0.2 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EER25801.1 - 0.052 12.6 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EER25801.1 - 0.11 13.0 0.4 12 6.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER25801.1 - 0.2 10.3 2.5 4 6.0 0.4 3.1 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 EER25801.1 - 0.73 8.8 4.5 1.1 8.3 0.4 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EER25801.1 - 1.6 7.7 6.2 0.56 9.2 0.8 2.5 3 0 0 3 3 3 0 FAD binding domain DDE_1 PF03184.19 EER25802.1 - 4.7e-15 55.7 2.4 7.6e-15 55.0 2.4 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease AraC_binding PF02311.19 EER25802.1 - 0.1 12.5 0.6 0.2 11.5 0.1 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain Ras PF00071.22 EER25803.1 - 2e-39 134.8 0.0 3.1e-39 134.2 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EER25803.1 - 2.2e-28 98.9 0.0 3.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER25803.1 - 1.8e-11 43.8 0.0 1.8e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EER25803.1 - 0.00022 20.7 0.0 0.0003 20.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EER25803.1 - 0.00025 21.1 0.0 0.00042 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER25803.1 - 0.00059 19.4 0.0 0.004 16.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EER25803.1 - 0.0025 17.7 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EER25803.1 - 0.0038 16.7 0.0 0.0076 15.7 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EER25803.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PduV-EutP PF10662.9 EER25803.1 - 0.014 15.2 0.0 0.88 9.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 EER25803.1 - 0.027 14.6 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EER25803.1 - 0.075 13.4 0.0 0.44 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EER25803.1 - 0.088 13.1 0.0 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EER25803.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 EER25803.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ADH_N PF08240.12 EER25804.1 - 2.1e-33 114.5 2.0 2.1e-33 114.4 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER25804.1 - 4e-23 81.8 0.1 7.1e-23 81.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EER25804.1 - 6.5e-08 32.3 0.1 1.4e-07 31.2 0.1 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus FtsJ PF01728.19 EER25804.1 - 0.00057 20.0 0.0 0.00083 19.5 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase ADH_zinc_N_2 PF13602.6 EER25804.1 - 0.00066 20.7 0.0 0.0015 19.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EER25804.1 - 0.00078 18.8 0.8 0.0012 18.2 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EER25804.1 - 0.011 15.3 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 EER25804.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 EER25804.1 - 0.033 14.9 0.0 0.077 13.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.6 EER25804.1 - 0.085 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PrmA PF06325.13 EER25804.1 - 0.096 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.19 EER25804.1 - 0.18 11.2 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Mannosidase_ig PF17786.1 EER25805.1 - 2.5e-18 66.5 0.0 6.6e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EER25805.1 - 6.6e-10 39.6 0.1 2.5e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EER25805.1 - 0.0014 18.6 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EER25805.1 - 0.0048 16.0 0.6 0.012 14.7 0.4 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 EER25805.1 - 0.011 15.5 0.0 0.039 13.7 0.0 2.0 1 0 0 1 1 1 0 Ig-fold domain Ig_GlcNase PF18368.1 EER25805.1 - 0.076 13.2 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 Exo-beta-D-glucosaminidase Ig-fold domain FAD-oxidase_C PF02913.19 EER25806.1 - 2.8e-59 200.8 0.1 4.6e-59 200.1 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EER25806.1 - 3.5e-37 127.3 0.0 5.7e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain bZIP_1 PF00170.21 EER25807.1 - 1.2e-05 25.3 1.3 2.7e-05 24.2 1.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor GAT PF03127.14 EER25807.1 - 0.2 12.0 0.3 0.76 10.1 0.2 1.9 1 1 1 2 2 2 0 GAT domain MCM_bind PF09739.9 EER25808.1 - 6 5.2 9.2 15 3.9 9.2 1.6 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Na_Ca_ex PF01699.24 EER25809.1 - 3.8e-37 127.6 41.6 3.2e-21 75.9 18.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Het-C PF07217.11 EER25810.1 - 1e-240 800.1 0.0 1.3e-240 799.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C F-box PF00646.33 EER25811.1 - 0.00046 20.0 1.1 0.00097 19.0 0.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EER25811.1 - 0.017 15.0 0.3 0.049 13.5 0.3 1.8 1 0 0 1 1 1 0 F-box-like Clr5 PF14420.6 EER25812.1 - 9.7e-22 77.0 1.8 9.7e-22 77.0 1.8 2.2 2 0 0 2 2 2 1 Clr5 domain PIN_12 PF16289.5 EER25812.1 - 0.15 12.5 0.1 0.61 10.6 0.0 1.9 1 1 1 2 2 2 0 PIN domain Phytase-like PF13449.6 EER25814.1 - 6.5e-37 128.0 0.0 8.8e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase LYRIC PF15686.5 EER25815.1 - 9.5 5.7 18.2 15 5.0 18.2 1.2 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family AA_permease_N PF08403.10 EER25816.1 - 0.047 13.2 0.2 0.1 12.1 0.2 1.6 1 0 0 1 1 1 0 Amino acid permease N-terminal WBS_methylT PF12589.8 EER25816.1 - 0.14 12.9 5.3 1.4 9.7 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase involved in Williams-Beuren syndrome Coatomer_WDAD PF04053.14 EER25817.1 - 9.6e-143 476.4 0.0 1.9e-142 475.4 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EER25817.1 - 2.2e-37 126.4 22.9 3.2e-08 34.1 0.7 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25817.1 - 4.6e-09 36.5 1.7 0.11 12.8 0.0 6.1 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER25817.1 - 0.0018 18.2 0.1 1.4 8.8 0.0 3.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EER25817.1 - 0.013 14.2 6.3 0.97 8.0 0.2 3.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Clathrin PF00637.20 EER25817.1 - 0.015 15.1 0.0 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 Region in Clathrin and VPS Evr1_Alr PF04777.13 EER25818.1 - 7.1e-32 109.9 2.6 1.3e-31 109.0 2.6 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Adaptin_N PF01602.20 EER25820.1 - 7.1e-138 460.4 3.2 9.2e-138 460.0 3.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EER25820.1 - 7.3e-64 214.7 2.2 4.6e-60 202.3 0.6 2.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EER25820.1 - 7.8e-16 58.2 2.6 2.1e-06 28.0 0.0 5.8 2 1 5 7 7 7 3 HEAT repeats HEAT PF02985.22 EER25820.1 - 4.9e-12 45.0 1.7 0.028 14.6 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EER25820.1 - 0.00034 21.1 3.2 0.59 10.7 0.0 5.8 7 1 1 8 8 8 1 HEAT-like repeat CLASP_N PF12348.8 EER25820.1 - 0.0016 18.0 0.4 2.1 7.9 0.0 3.8 2 1 0 3 3 3 1 CLASP N terminal Arm PF00514.23 EER25820.1 - 0.0075 16.3 1.5 35 4.6 0.0 5.6 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat CAAP1 PF15335.6 EER25820.1 - 0.02 15.4 0.4 0.11 13.0 0.1 2.4 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 PDCD2_C PF04194.13 EER25820.1 - 0.039 14.0 0.1 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain TLD PF07534.16 EER25821.1 - 2.1e-05 24.8 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 TLD VID27 PF08553.10 EER25822.1 - 2e-195 648.8 0.0 2.7e-195 648.4 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EER25822.1 - 1.5e-75 252.8 0.3 1.5e-75 252.8 0.3 3.0 3 1 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 EER25822.1 - 2.2e-46 156.6 3.8 5.9e-46 155.3 2.4 2.2 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 EER25822.1 - 0.036 14.4 1.4 0.21 11.9 1.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) DNA_pol_phi PF04931.13 EER25822.1 - 0.86 7.6 8.4 1.5 6.9 8.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi tRNA_m1G_MT PF01746.21 EER25823.1 - 2e-24 86.4 4.5 4.5e-18 65.6 0.0 2.8 3 0 0 3 3 3 2 tRNA (Guanine-1)-methyltransferase ORC_WH_C PF18137.1 EER25823.1 - 0.89 9.6 7.7 0.64 10.1 0.1 2.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal GRIM-19 PF06212.12 EER25824.1 - 2.3e-23 82.6 0.2 6.3e-23 81.2 0.2 1.6 1 1 0 1 1 1 1 GRIM-19 protein Xpo1 PF08389.12 EER25825.1 - 1.8e-07 31.4 9.6 8e-05 22.7 0.0 4.7 5 0 0 5 5 5 3 Exportin 1-like protein IBN_N PF03810.19 EER25825.1 - 0.044 13.7 0.0 1.7 8.6 0.1 3.2 2 0 0 2 2 2 0 Importin-beta N-terminal domain Glyco_hydro_5_C PF18564.1 EER25826.1 - 1.9e-19 70.0 0.0 4.5e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EER25826.1 - 3.2e-07 30.0 4.5 0.00011 21.8 2.4 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EER25826.1 - 0.012 15.0 0.1 3.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Beta-galactosidase TPR_2 PF07719.17 EER25827.1 - 1.1e-30 103.2 45.1 0.0005 20.0 0.1 18.0 20 0 0 20 20 18 7 Tetratricopeptide repeat TPR_17 PF13431.6 EER25827.1 - 2e-27 93.5 13.8 0.0048 17.2 0.0 14.6 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_8 PF13181.6 EER25827.1 - 3.3e-26 89.3 29.6 0.0032 17.6 0.0 15.0 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_14 PF13428.6 EER25827.1 - 7.7e-26 88.6 31.9 0.00013 22.5 0.2 17.0 13 4 4 17 17 16 4 Tetratricopeptide repeat TPR_1 PF00515.28 EER25827.1 - 4.9e-25 86.3 34.9 8.5e-05 22.2 0.1 15.4 17 0 0 17 17 16 5 Tetratricopeptide repeat TPR_19 PF14559.6 EER25827.1 - 3.3e-24 85.2 30.4 3.6e-08 33.8 0.5 11.8 11 2 2 13 13 13 6 Tetratricopeptide repeat TPR_16 PF13432.6 EER25827.1 - 3.2e-23 82.1 32.7 0.00013 22.5 0.7 11.8 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 EER25827.1 - 2.3e-19 68.8 22.4 0.002 17.8 0.0 11.4 11 1 1 12 12 11 5 TPR repeat TPR_12 PF13424.6 EER25827.1 - 1e-16 61.0 48.2 3.7e-08 33.5 0.0 13.2 9 3 3 13 13 13 4 Tetratricopeptide repeat TPR_6 PF13174.6 EER25827.1 - 3.8e-12 46.0 30.2 0.0033 18.0 0.0 14.5 18 0 0 18 18 16 3 Tetratricopeptide repeat TPR_7 PF13176.6 EER25827.1 - 2.5e-10 39.6 25.3 0.00031 20.6 0.1 11.7 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_9 PF13371.6 EER25827.1 - 7.5e-06 26.0 11.4 0.81 9.9 1.5 7.0 7 2 0 7 7 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EER25827.1 - 0.00015 21.9 14.2 0.1 12.8 0.2 7.0 8 1 0 8 8 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 EER25827.1 - 0.00043 20.4 0.0 0.0015 18.6 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EER25827.1 - 0.00095 18.7 1.8 0.0017 17.9 0.1 2.3 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_15 PF13429.6 EER25827.1 - 0.0018 17.6 25.7 0.11 11.7 0.1 7.8 6 4 2 9 9 9 1 Tetratricopeptide repeat DUF2989 PF11207.8 EER25827.1 - 0.0022 17.8 4.9 5.8 6.6 0.0 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2989) ChAPs PF09295.10 EER25827.1 - 0.0046 16.0 1.1 37 3.1 0.1 5.2 4 1 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.22 EER25827.1 - 0.0084 15.8 1.6 14 5.6 0.0 4.0 4 0 0 4 4 3 0 Protein prenyltransferase alpha subunit repeat Sel1 PF08238.12 EER25827.1 - 0.025 15.3 1.2 19 6.1 0.0 3.7 3 0 0 3 3 2 0 Sel1 repeat Ribosomal_L17 PF01196.19 EER25827.1 - 0.1 13.5 0.0 1.1 10.2 0.0 2.7 2 0 0 2 2 2 0 Ribosomal protein L17 TPR_10 PF13374.6 EER25827.1 - 0.1 12.5 22.8 3 7.8 0.1 8.8 10 0 0 10 10 10 0 Tetratricopeptide repeat RMI1_N PF08585.12 EER25828.1 - 1.6e-61 207.8 0.0 1.9e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Vps51 PF08700.11 EER25829.1 - 4.2e-25 87.7 0.0 1.1e-24 86.3 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EER25829.1 - 0.0015 18.7 0.1 0.0039 17.4 0.0 1.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Dor1 PF04124.12 EER25829.1 - 0.016 13.9 0.2 0.02 13.6 0.2 1.2 1 0 0 1 1 1 0 Dor1-like family FlgN PF05130.12 EER25829.1 - 1.3 9.6 6.2 5.2 7.6 0.4 2.4 1 1 1 2 2 2 0 FlgN protein WD40 PF00400.32 EER25830.1 - 0.096 13.6 0.3 19 6.3 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-MYST PF17772.1 EER25830.1 - 0.17 11.5 0.1 0.39 10.4 0.1 1.6 1 0 0 1 1 1 0 MYST family zinc finger domain CSN8_PSD8_EIF3K PF10075.9 EER25831.1 - 4.7e-20 72.0 0.0 9.9e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EER25831.1 - 0.00094 18.7 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family AIG2_2 PF13772.6 EER25833.1 - 0.0011 19.3 0.1 0.044 14.2 0.1 2.3 1 1 0 1 1 1 1 AIG2-like family eIF-5_eIF-2B PF01873.17 EER25836.1 - 1.7e-41 140.8 0.2 3.6e-41 139.7 0.2 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 ORC6 PF05460.13 EER25836.1 - 0.11 11.7 3.9 0.15 11.3 3.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TF_Zn_Ribbon PF08271.12 EER25836.1 - 0.28 10.7 1.8 0.55 9.8 1.8 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Arc_trans_TRASH PF08394.10 EER25836.1 - 1.5 9.2 7.5 1.3 9.5 0.4 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.12 EER25836.1 - 4.7 7.1 6.7 25 4.8 4.0 2.7 2 1 1 3 3 3 0 HypF finger AIM24 PF01987.17 EER25837.1 - 1.1e-55 188.5 0.6 1.3e-55 188.3 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Abhydrolase_1 PF00561.20 EER25838.1 - 5.3e-07 29.5 0.1 6.2e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER25838.1 - 2.6e-06 28.2 0.3 3e-06 28.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER25838.1 - 0.00064 19.1 0.0 0.00073 18.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SH3_1 PF00018.28 EER25839.1 - 7.5e-15 54.3 0.0 1.2e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER25839.1 - 1.7e-13 50.1 0.0 3.1e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EER25839.1 - 5.1e-08 32.5 0.0 8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain MBF1 PF08523.10 EER25840.1 - 1.8e-26 92.4 0.4 1.8e-26 92.4 0.4 1.7 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EER25840.1 - 1.4e-12 47.4 0.1 2.2e-12 46.8 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EER25840.1 - 1.2e-05 25.6 0.0 3.2e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Iso_dh PF00180.20 EER25841.1 - 5e-70 236.4 0.0 5.9e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FTHFS PF01268.19 EER25842.1 - 5.1e-253 840.3 0.1 1.2e-252 839.1 0.0 1.6 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EER25842.1 - 9.6e-68 226.5 1.0 9.6e-68 226.5 1.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EER25842.1 - 1.4e-38 131.7 0.1 3.1e-38 130.6 0.1 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EER25842.1 - 0.0065 15.4 0.1 0.016 14.2 0.1 1.5 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AdoHcyase_NAD PF00670.21 EER25842.1 - 0.033 14.3 0.2 4.9 7.2 0.1 3.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GTP_EFTU PF00009.27 EER25842.1 - 0.045 13.3 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CREPT PF16566.5 EER25842.1 - 0.31 11.2 0.7 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour WD40 PF00400.32 EER25843.1 - 2e-25 88.6 0.7 2.1e-06 28.3 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25843.1 - 3.4e-11 43.3 0.0 0.016 15.5 0.0 5.4 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 EER25843.1 - 0.0033 17.2 0.3 0.0076 16.0 0.3 1.6 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 EER25843.1 - 0.0059 16.2 0.4 0.035 13.7 0.5 2.0 1 1 1 2 2 2 1 PQQ-like domain DUF1708 PF08101.11 EER25844.1 - 4e-178 593.0 0.0 5.5e-178 592.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF3602 PF12223.8 EER25845.1 - 1e-19 70.9 1.2 1.8e-19 70.1 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3602) Mito_carr PF00153.27 EER25846.1 - 1.8e-48 162.4 4.4 1.5e-18 66.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 EER25847.1 - 2e-07 31.3 0.0 0.29 11.6 0.0 3.2 1 1 2 3 3 3 3 CBS domain MFS_2 PF13347.6 EER25848.1 - 4.6e-09 35.4 10.7 4.6e-09 35.4 10.7 3.3 2 2 0 2 2 2 1 MFS/sugar transport protein Nuc_H_symport PF03825.16 EER25848.1 - 0.0064 15.5 0.9 0.0064 15.5 0.9 3.0 3 0 0 3 3 3 1 Nucleoside H+ symporter MFS_1_like PF12832.7 EER25848.1 - 0.023 13.6 6.2 0.022 13.6 0.7 3.0 2 1 1 3 3 3 0 MFS_1 like family DUF1056 PF06341.11 EER25848.1 - 0.075 13.3 1.3 0.5 10.7 1.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) G6PD_C PF02781.16 EER25849.1 - 3.4e-116 387.5 0.0 5.4e-116 386.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EER25849.1 - 1.9e-61 207.8 0.0 3.2e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain MFS_1 PF07690.16 EER25850.1 - 8.3e-49 166.4 55.0 7.9e-48 163.2 55.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EER25850.1 - 2.2e-20 72.6 16.9 3.8e-20 71.9 16.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER25850.1 - 5.9e-13 48.5 8.8 5.9e-13 48.5 8.8 3.6 4 0 0 4 4 4 2 Sugar (and other) transporter OATP PF03137.20 EER25850.1 - 0.0018 16.6 9.3 0.011 14.0 1.4 3.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Glyoxalase PF00903.25 EER25851.1 - 0.019 15.2 0.0 0.042 14.0 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_S49 PF01343.18 EER25851.1 - 0.035 14.1 0.0 0.053 13.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 EF-hand_1 PF00036.32 EER25852.1 - 1.3e-20 71.4 3.1 3.8e-06 26.1 0.2 4.7 4 1 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EER25852.1 - 2.1e-18 66.5 0.2 3.6e-07 30.5 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EER25852.1 - 2.6e-18 64.3 1.5 0.00012 21.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EER25852.1 - 1.6e-17 63.0 0.8 9.9e-07 28.5 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EER25852.1 - 1.8e-10 39.8 5.1 0.00024 20.4 0.1 4.0 4 1 0 4 4 4 3 EF hand ChaC PF04752.12 EER25853.1 - 1.5e-28 100.1 0.0 2.6e-28 99.3 0.0 1.4 2 0 0 2 2 2 1 ChaC-like protein RRM_1 PF00076.22 EER25854.1 - 4.5e-24 84.1 0.0 5.6e-24 83.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER25854.1 - 0.00057 19.9 0.0 0.001 19.1 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 EER25854.1 - 0.13 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif DUF2306 PF10067.9 EER25856.1 - 9.3e-14 51.9 13.8 1.4e-13 51.2 13.5 1.5 1 1 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.12 EER25856.1 - 0.0021 18.3 1.0 0.0021 18.3 1.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF420) TBCC PF07986.12 EER25858.1 - 3.3e-28 97.8 0.7 5.2e-28 97.2 0.7 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EER25858.1 - 3.2e-10 40.5 0.2 5.3e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Dynamitin PF04912.14 EER25858.1 - 0.035 13.4 0.1 0.048 13.0 0.1 1.1 1 0 0 1 1 1 0 Dynamitin RrnaAD PF00398.20 EER25859.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase LdpA_C PF12617.8 EER25859.1 - 0.054 13.1 0.1 0.099 12.2 0.1 1.3 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal JAB PF01398.21 EER25860.1 - 1.1e-13 51.2 0.0 2.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EER25860.1 - 4.6e-07 30.0 0.2 8e-07 29.2 0.2 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EER25860.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MIT PF04212.18 EER25860.1 - 0.019 15.0 0.1 0.067 13.3 0.1 2.0 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 EER25862.1 - 2.2e-13 50.2 0.0 3.4e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25862.1 - 6.5e-07 28.9 0.0 9.9e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER25862.1 - 0.0076 16.2 0.3 0.013 15.4 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EER25862.1 - 0.035 12.9 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Fungal_trans PF04082.18 EER25863.1 - 8.2e-14 51.3 0.2 5.2e-13 48.6 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER25863.1 - 1e-07 31.9 10.2 1e-07 31.9 10.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CITED PF04487.12 EER25863.1 - 0.085 12.9 4.9 0.18 11.8 4.9 1.5 1 0 0 1 1 1 0 CITED Sugar_tr PF00083.24 EER25864.1 - 4.5e-35 121.4 3.3 6e-35 121.0 3.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER25864.1 - 7.7e-20 71.1 9.6 9.6e-20 70.8 9.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 EER25864.1 - 6.8 4.9 7.4 4.2 5.5 5.3 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family APH PF01636.23 EER25865.1 - 2.4e-17 63.7 0.0 1.4e-16 61.1 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family YicC_N PF03755.13 EER25865.1 - 0.078 13.4 0.0 0.29 11.6 0.0 1.8 2 0 0 2 2 2 0 YicC-like family, N-terminal region SRF-TF PF00319.18 EER25866.1 - 2.1e-23 81.6 0.3 3.1e-23 81.0 0.3 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribosomal_L35Ae PF01247.18 EER25867.1 - 4.1e-42 142.3 0.3 4.8e-42 142.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EER25867.1 - 0.00027 21.1 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.9 EER25868.1 - 6.2e-26 90.9 0.1 6.2e-26 90.9 0.1 3.1 3 1 0 3 3 3 1 Uncharacterised protein (DUF2406) SAM_adeno_trans PF01887.16 EER25868.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase DUF5345 PF17280.2 EER25868.1 - 1.9 8.5 6.6 3.1 7.8 5.6 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5345) VMA21 PF09446.10 EER25869.1 - 1e-12 47.9 9.1 1.4e-12 47.6 9.1 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 EER25870.1 - 4.6e-51 173.6 0.1 7.3e-51 172.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER25870.1 - 8.8e-19 67.9 0.0 3.1e-18 66.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER25870.1 - 1.7e-08 34.6 0.0 3.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EER25870.1 - 1.6e-06 27.6 0.1 3.6e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EER25870.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Peptidase_M28 PF04389.17 EER25871.1 - 1.8e-42 145.3 0.1 2.6e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EER25871.1 - 1.2e-14 54.0 0.7 3.1e-14 52.7 0.2 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EER25871.1 - 0.049 13.3 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Dus PF01207.17 EER25872.1 - 9.4e-42 143.2 0.0 2.3e-41 141.9 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PucR PF07905.11 EER25872.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Pyrophosphatase PF00719.19 EER25873.1 - 1.6e-57 193.8 0.2 2.1e-57 193.4 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec20 PF03908.13 EER25874.1 - 9.8e-17 60.7 1.8 9.8e-17 60.7 1.8 2.1 2 0 0 2 2 2 1 Sec20 Cep57_MT_bd PF06657.13 EER25874.1 - 5.7 7.5 9.5 0.64 10.5 1.0 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Rep_fac_C PF08542.11 EER25875.1 - 3.2e-19 69.1 0.0 6.7e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EER25875.1 - 2.7e-15 57.0 0.0 1.1e-14 55.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EER25875.1 - 1.4e-12 47.7 0.0 2.2e-11 43.8 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EER25875.1 - 1.3e-09 38.2 0.0 2.6e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EER25875.1 - 1.4e-05 25.5 0.1 0.0015 18.9 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EER25875.1 - 4.8e-05 23.2 0.0 0.00012 21.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 EER25875.1 - 7.5e-05 23.0 0.0 0.00024 21.3 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_22 PF13401.6 EER25875.1 - 8.2e-05 22.9 0.0 0.00079 19.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EER25875.1 - 8.8e-05 22.4 0.1 0.00028 20.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EER25875.1 - 0.00036 20.0 0.1 0.02 14.3 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EER25875.1 - 0.0022 17.7 0.0 0.0061 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EER25875.1 - 0.0038 17.2 0.0 0.0088 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EER25875.1 - 0.005 16.1 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EER25875.1 - 0.0056 17.0 0.0 0.028 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EER25875.1 - 0.0077 15.8 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 EER25875.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_5 PF07728.14 EER25875.1 - 0.011 15.8 0.3 0.12 12.4 0.1 2.5 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EER25875.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ResIII PF04851.15 EER25875.1 - 0.012 15.6 0.0 0.26 11.3 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TPM_phosphatase PF04536.14 EER25875.1 - 0.018 15.2 0.1 0.44 10.7 0.0 2.5 2 0 0 2 2 2 0 TPM domain AAA_18 PF13238.6 EER25875.1 - 0.027 15.0 0.0 0.18 12.4 0.0 2.3 1 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EER25875.1 - 0.044 14.0 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EER25875.1 - 0.046 13.6 0.0 0.53 10.1 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EER25875.1 - 0.047 13.4 0.1 0.33 10.7 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_23 PF13476.6 EER25875.1 - 0.051 14.1 0.0 0.077 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EER25875.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF1746 PF08508.10 EER25877.1 - 2.1e-42 144.1 2.0 2.9e-42 143.6 2.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) DUF4677 PF15726.5 EER25877.1 - 0.0065 16.7 1.7 0.017 15.3 1.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4677) CLP_protease PF00574.23 EER25878.1 - 1.7e-76 256.1 0.0 2.2e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Clp protease Clr5 PF14420.6 EER25878.1 - 0.097 12.9 0.4 0.2 11.9 0.4 1.4 1 0 0 1 1 1 0 Clr5 domain Tugs PF17840.1 EER25878.1 - 0.19 11.9 1.5 0.37 11.0 1.5 1.4 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain RRG8 PF17068.5 EER25879.1 - 0.0036 16.8 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial Hydrolase_6 PF13344.6 EER25880.1 - 2.3e-29 101.5 0.0 3.7e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER25880.1 - 1.6e-15 56.9 0.0 4.9e-15 55.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EER25880.1 - 9.2e-11 42.4 0.0 7.7e-09 36.1 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EER25880.1 - 6.1e-05 23.2 0.1 0.056 13.5 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EER25880.1 - 0.17 11.5 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Sugar_tr PF00083.24 EER25881.1 - 2.2e-44 152.0 10.5 3e-44 151.6 10.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER25881.1 - 2.7e-38 131.8 25.6 3e-25 88.9 10.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EER25881.1 - 1.1e-07 31.0 0.0 0.00049 19.1 0.0 3.4 2 1 2 4 4 4 3 MFS_1 like family MFS_4 PF06779.14 EER25881.1 - 0.00095 18.6 1.6 0.0017 17.7 1.6 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ATG22 PF11700.8 EER25881.1 - 0.02 13.6 2.2 0.14 10.8 0.1 2.3 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like UPF0239 PF06783.11 EER25881.1 - 0.033 14.4 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) BT1 PF03092.16 EER25881.1 - 0.095 10.9 0.1 5.8 5.0 0.0 2.2 1 1 1 2 2 2 0 BT1 family LacY_symp PF01306.19 EER25881.1 - 9.6 4.9 16.1 0.56 8.9 0.9 2.8 2 2 1 3 3 3 0 LacY proton/sugar symporter Peptidase_M18 PF02127.15 EER25882.1 - 1.9e-164 547.6 0.0 2.1e-164 547.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.32 EER25883.1 - 7.8e-24 83.5 13.3 0.00014 22.5 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER25883.1 - 3.2e-13 49.8 5.3 0.00038 20.7 0.2 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER25883.1 - 3.2e-08 33.7 0.3 0.011 15.6 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EER25883.1 - 0.071 12.1 0.0 0.29 10.1 0.0 1.9 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EER25883.1 - 0.43 9.5 1.9 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain E3_binding PF02817.17 EER25884.1 - 1.1e-11 44.8 0.1 4.1e-11 43.0 0.1 2.0 2 0 0 2 2 2 1 e3 binding domain APH PF01636.23 EER25887.1 - 5.4e-10 39.6 0.0 5.7e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER25887.1 - 2.3e-05 24.1 0.0 3.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EER25887.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EER25887.1 - 0.019 14.3 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 EER25887.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 EER25887.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DUF2838 PF10998.8 EER25888.1 - 5.1e-43 145.8 11.5 5.1e-43 145.8 11.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) L27_2 PF09045.10 EER25888.1 - 0.0088 16.0 0.2 0.66 10.0 0.0 3.0 3 0 0 3 3 3 1 L27_2 Bot1p PF12298.8 EER25888.1 - 0.15 12.2 1.9 0.25 11.5 1.9 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein MtrB PF05440.12 EER25888.1 - 0.19 12.2 0.0 2.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Exonuc_VII_L PF02601.15 EER25888.1 - 0.19 11.3 0.9 0.29 10.6 0.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SMC_N PF02463.19 EER25889.1 - 4.9e-59 199.4 0.0 4.1e-58 196.4 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EER25889.1 - 2.2e-30 105.4 0.6 8.3e-30 103.5 0.0 2.4 3 0 0 3 3 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EER25889.1 - 7.5e-12 45.7 9.6 1.3e-05 25.1 0.2 3.9 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EER25889.1 - 7.7e-08 32.0 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EER25889.1 - 0.00015 22.3 35.4 0.00015 22.3 35.4 6.8 3 2 2 5 5 4 1 AAA domain Shugoshin_N PF07558.11 EER25889.1 - 0.0031 17.3 2.0 0.03 14.2 0.2 3.2 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region ATG16 PF08614.11 EER25889.1 - 0.0045 17.2 12.5 0.0045 17.2 12.5 7.0 3 2 1 5 5 4 1 Autophagy protein 16 (ATG16) SbcCD_C PF13558.6 EER25889.1 - 0.005 17.1 0.0 0.02 15.1 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF948 PF06103.11 EER25889.1 - 0.0067 16.7 19.9 2 8.8 0.8 7.1 5 2 1 6 6 6 2 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 EER25889.1 - 0.014 15.7 1.1 0.014 15.7 1.1 8.5 3 2 3 6 6 4 0 Outer membrane protein (OmpH-like) Laminin_II PF06009.12 EER25889.1 - 0.017 15.1 0.6 0.017 15.1 0.6 8.7 4 3 5 9 9 9 0 Laminin Domain II TMP_2 PF06791.13 EER25889.1 - 0.23 11.1 3.7 0.47 10.1 1.6 2.6 2 1 1 3 3 3 0 Prophage tail length tape measure protein DUF1664 PF07889.12 EER25889.1 - 0.25 11.4 65.4 0.025 14.6 3.6 9.1 4 3 5 9 9 9 0 Protein of unknown function (DUF1664) ABC_tran PF00005.27 EER25889.1 - 1.4 9.5 0.0 1.4 9.5 0.0 6.1 4 3 0 4 4 2 0 ABC transporter NUDIX PF00293.28 EER25891.1 - 6.8e-09 35.9 0.2 1.5e-08 34.8 0.0 1.7 2 1 0 2 2 2 1 NUDIX domain LETM1 PF07766.13 EER25892.1 - 1.1e-103 346.3 0.0 1.8e-103 345.6 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 EER25892.1 - 9.6e-05 22.0 0.1 0.077 12.8 0.0 3.2 3 0 0 3 3 3 2 SAP domain BPL_N PF09825.9 EER25892.1 - 0.059 12.5 0.0 0.059 12.5 0.0 2.2 2 0 0 2 2 2 0 Biotin-protein ligase, N terminal Glyco_hydro_38N PF01074.22 EER25893.1 - 7.2e-90 301.3 0.4 1.1e-89 300.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EER25893.1 - 1.3e-58 198.6 0.3 8.8e-58 195.9 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EER25893.1 - 3.6e-28 97.6 0.0 8.7e-28 96.3 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EER25893.1 - 6.8e-12 45.3 0.0 3.8e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain 7TMR-DISMED2 PF07696.11 EER25893.1 - 0.042 13.9 0.3 0.28 11.2 0.0 2.4 3 0 0 3 3 3 0 7TMR-DISM extracellular 2 NuA4 PF09340.10 EER25894.1 - 2.9e-27 94.3 0.9 5.8e-27 93.4 0.1 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Senescence_reg PF04520.13 EER25894.1 - 0.033 15.0 3.6 0.056 14.3 3.6 1.3 1 0 0 1 1 1 0 Senescence regulator ORC6 PF05460.13 EER25894.1 - 6.5 5.9 7.2 6.2 6.0 6.1 1.5 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Ctr PF04145.15 EER25895.1 - 6.2e-31 108.0 0.0 7.5e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Neurensin PF14927.6 EER25895.1 - 0.093 12.4 1.6 0.17 11.6 1.6 1.8 1 1 0 1 1 1 0 Neurensin Cupin_8 PF13621.6 EER25896.1 - 9e-15 55.1 0.1 6.7e-13 48.9 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EER25896.1 - 4.9e-10 39.8 1.3 0.00018 21.9 0.4 2.6 2 0 0 2 2 2 2 JmjC domain, hydroxylase F-box-like PF12937.7 EER25896.1 - 5e-06 26.3 0.0 9.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER25896.1 - 0.0062 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.12 EER25896.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Cupin superfamily protein Elongin_A PF06881.11 EER25896.1 - 0.18 12.3 0.2 0.41 11.2 0.0 1.6 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DEAD PF00270.29 EER25897.1 - 3.3e-45 154.0 1.2 5.9e-45 153.2 1.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER25897.1 - 1.9e-32 111.9 0.3 1.2e-31 109.3 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER25897.1 - 1.1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EER25897.1 - 2.9e-05 23.9 0.2 5.3e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EER25897.1 - 0.00065 20.0 1.1 0.0031 17.8 0.7 2.1 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 EER25897.1 - 0.0035 16.7 0.0 0.0077 15.6 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EER25897.1 - 0.0049 17.2 0.4 0.02 15.2 0.4 2.1 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EER25897.1 - 0.043 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Helicase fragilysinNterm PF16376.5 EER25897.1 - 0.083 12.6 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of fragilysin Flavi_DEAD PF07652.14 EER25897.1 - 0.097 12.6 0.1 0.7 9.9 0.1 2.4 1 1 0 1 1 1 0 Flavivirus DEAD domain Prominin PF05478.11 EER25898.1 - 0.0056 14.7 0.2 0.0084 14.1 0.2 1.1 1 0 0 1 1 1 1 Prominin ERM PF00769.19 EER25898.1 - 0.0064 16.3 3.8 0.0064 16.3 3.8 2.2 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Retrotrans_gag PF03732.17 EER25898.1 - 0.053 13.8 0.2 0.21 11.9 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein DUF948 PF06103.11 EER25898.1 - 0.083 13.2 0.7 32 4.9 0.0 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Seryl_tRNA_N PF02403.22 EER25898.1 - 0.11 12.8 9.9 0.69 10.2 0.1 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 EER25898.1 - 0.11 12.5 1.9 0.43 10.6 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KIAA1430 PF13879.6 EER25898.1 - 0.14 13.0 0.3 0.14 13.0 0.3 2.5 2 0 0 2 2 2 0 KIAA1430 homologue DUF4763 PF15960.5 EER25898.1 - 0.34 10.2 8.5 0.88 8.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) FliJ PF02050.16 EER25898.1 - 0.35 11.1 9.9 7.7 6.8 0.1 2.9 2 1 1 3 3 3 0 Flagellar FliJ protein DUF724 PF05266.14 EER25898.1 - 1.4 8.7 9.1 4.8 7.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF724) TMF_TATA_bd PF12325.8 EER25898.1 - 1.7 8.8 10.9 1.9 8.8 0.1 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.9 EER25898.1 - 2.7 7.0 8.4 1.5 7.9 2.0 2.7 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4618 PF15397.6 EER25898.1 - 7.4 5.9 9.6 4.4 6.6 2.1 3.0 2 1 2 4 4 4 0 Domain of unknown function (DUF4618) FAA_hydrolase PF01557.18 EER25899.1 - 1.2e-56 191.9 0.0 1.4e-56 191.6 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PWI PF01480.17 EER25901.1 - 1.7e-31 108.3 0.8 5.8e-31 106.6 0.0 2.0 2 0 0 2 2 2 1 PWI domain DUF2951 PF11166.8 EER25901.1 - 0.7 10.1 4.6 3.2 8.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Pkinase PF00069.25 EER25903.1 - 7e-47 160.0 0.0 1e-46 159.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25903.1 - 8.9e-17 61.2 0.0 1.4e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER25903.1 - 0.0054 16.1 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EER25903.1 - 0.0074 16.2 2.0 1.3 8.8 0.2 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 EER25903.1 - 0.032 13.8 0.2 0.062 12.9 0.2 1.5 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EER25903.1 - 0.09 11.5 0.0 0.23 10.2 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EER25903.1 - 0.12 11.7 0.3 0.25 10.7 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L21p PF00829.21 EER25904.1 - 2.1e-09 37.6 0.0 2.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Ribosomal_S8e PF01201.22 EER25905.1 - 6.4e-46 155.9 2.9 9.3e-46 155.4 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Pannexin_like PF12534.8 EER25905.1 - 7.7 5.5 5.6 11 5.0 5.6 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Fungal_trans PF04082.18 EER25906.1 - 7e-20 71.2 0.9 1.1e-19 70.6 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER25906.1 - 0.0014 18.7 6.0 0.0027 17.8 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.20 EER25907.1 - 1.3e-52 179.3 0.2 2.2e-52 178.6 0.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 EER25907.1 - 1.5e-29 103.1 0.0 2.4e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Tyosinase C-terminal domain Metallophos PF00149.28 EER25908.1 - 6.3e-09 36.6 0.5 1.9e-08 35.1 0.5 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Cation_efflux PF01545.21 EER25909.1 - 1.3e-52 178.5 0.2 2.4e-52 177.6 0.2 1.4 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EER25909.1 - 0.078 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter DUF202 PF02656.15 EER25910.1 - 2.2e-15 56.8 0.7 2.2e-15 56.8 0.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2970 PF11174.8 EER25910.1 - 2.9 7.8 7.4 4.2 7.3 3.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) AAA PF00004.29 EER25911.1 - 2.3e-38 131.6 0.0 2.7e-13 50.5 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_lid_6 PF17866.1 EER25911.1 - 1.6e-18 66.7 4.0 6.7e-09 35.8 0.1 3.8 3 0 0 3 3 3 2 AAA lid domain AAA_30 PF13604.6 EER25911.1 - 1.2e-12 48.0 0.0 0.0037 17.0 0.0 3.5 3 0 0 3 3 3 3 AAA domain RuvB_N PF05496.12 EER25911.1 - 1.5e-12 47.5 0.1 0.00031 20.5 0.0 3.7 3 1 0 3 3 3 3 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EER25911.1 - 2.8e-12 46.8 0.2 0.0046 17.0 0.0 4.2 4 1 0 4 4 3 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EER25911.1 - 2.9e-12 47.0 8.0 0.082 13.2 0.0 6.9 4 3 1 5 5 4 3 AAA domain Viral_helicase1 PF01443.18 EER25911.1 - 9.1e-09 35.4 2.1 0.038 13.7 0.0 3.8 4 0 0 4 4 3 3 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 EER25911.1 - 2.3e-08 34.3 1.5 0.086 13.0 0.0 4.1 4 0 0 4 4 3 2 AAA domain Mg_chelatase PF01078.21 EER25911.1 - 6.3e-08 32.3 0.8 0.63 9.4 0.1 4.7 3 2 2 5 5 5 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EER25911.1 - 1.3e-07 32.0 3.5 0.45 10.8 0.1 5.4 4 1 0 4 4 4 2 AAA domain Sigma54_activat PF00158.26 EER25911.1 - 1.9e-07 30.9 0.3 0.55 9.9 0.0 4.7 3 2 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 EER25911.1 - 2.3e-07 31.4 0.8 0.48 10.8 0.0 4.6 3 1 0 4 4 4 2 AAA ATPase domain TniB PF05621.11 EER25911.1 - 3.4e-07 29.9 0.1 0.032 13.6 0.0 4.7 4 2 1 5 5 4 2 Bacterial TniB protein AAA_2 PF07724.14 EER25911.1 - 7.3e-07 29.5 0.0 0.074 13.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EER25911.1 - 8.5e-07 29.3 0.0 2.1 8.8 0.0 4.0 4 0 0 4 4 3 2 RNA helicase AAA_24 PF13479.6 EER25911.1 - 7.6e-06 25.8 1.2 2.7 7.6 0.0 4.1 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EER25911.1 - 1.2e-05 25.1 0.1 0.4 10.4 0.0 3.8 4 0 0 4 4 3 1 IstB-like ATP binding protein AAA_18 PF13238.6 EER25911.1 - 1.6e-05 25.4 4.8 1.4 9.5 0.3 4.6 4 1 0 4 4 3 2 AAA domain Sigma54_activ_2 PF14532.6 EER25911.1 - 5.4e-05 23.3 0.0 1.2 9.3 0.0 3.6 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_7 PF12775.7 EER25911.1 - 5.5e-05 22.8 0.1 2.6 7.5 0.0 3.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_25 PF13481.6 EER25911.1 - 7.5e-05 22.4 0.8 1.9 8.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain ResIII PF04851.15 EER25911.1 - 0.00037 20.6 0.2 8.6 6.3 0.0 4.9 4 1 1 5 5 5 0 Type III restriction enzyme, res subunit MCM PF00493.23 EER25911.1 - 0.0012 18.0 0.1 0.12 11.5 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain AAA_29 PF13555.6 EER25911.1 - 0.0025 17.5 0.0 10 5.9 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain TsaE PF02367.17 EER25911.1 - 0.0028 17.7 0.1 0.13 12.2 0.0 2.9 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EER25911.1 - 0.0037 16.8 0.3 13 5.1 0.1 3.4 3 0 0 3 3 3 0 PhoH-like protein AAA_19 PF13245.6 EER25911.1 - 0.0064 16.8 6.6 11 6.4 0.0 4.9 3 3 3 6 6 5 0 AAA domain NTPase_1 PF03266.15 EER25911.1 - 0.007 16.3 0.3 3.9 7.4 0.0 3.3 3 0 0 3 3 3 1 NTPase AAA_17 PF13207.6 EER25911.1 - 0.0084 16.5 1.4 1.7 9.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EER25911.1 - 0.013 15.5 3.3 4 7.3 0.0 4.7 5 1 1 6 6 5 0 NACHT domain T2SSE PF00437.20 EER25911.1 - 0.014 14.5 0.0 4 6.4 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EER25911.1 - 0.033 13.4 0.0 2.8 7.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin SRP54 PF00448.22 EER25911.1 - 0.053 13.2 0.2 22 4.6 0.1 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATPase PF06745.13 EER25911.1 - 0.056 12.8 0.7 4.6 6.5 0.0 3.1 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 EER25911.1 - 0.063 13.1 12.3 2.1 8.1 0.0 4.8 5 0 0 5 5 3 0 AAA domain NB-ARC PF00931.22 EER25911.1 - 0.13 11.4 0.1 26 3.9 0.0 3.3 3 0 0 3 3 3 0 NB-ARC domain ATP_bind_1 PF03029.17 EER25911.1 - 0.31 10.8 2.5 40 3.9 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MADF_DNA_bdg PF10545.9 EER25911.1 - 0.6 10.5 2.1 0.82 10.0 0.0 2.3 2 0 0 2 2 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ABC_tran PF00005.27 EER25911.1 - 0.75 10.3 5.1 48 4.5 0.0 4.1 4 0 0 4 4 3 0 ABC transporter Methyltransf_25 PF13649.6 EER25913.1 - 2.2e-17 63.5 0.2 2e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER25913.1 - 2.3e-16 60.2 0.4 4.3e-16 59.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER25913.1 - 2.1e-14 53.7 0.0 3e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER25913.1 - 5.9e-14 52.6 0.0 9.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER25913.1 - 2.9e-13 49.9 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER25913.1 - 9.6e-06 25.2 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EER25913.1 - 0.00022 20.7 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EER25913.1 - 0.00035 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EER25913.1 - 0.00058 19.7 0.0 0.0012 18.6 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 EER25913.1 - 0.001 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 EER25913.1 - 0.005 16.3 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EER25913.1 - 0.0051 15.9 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.11 EER25913.1 - 0.013 14.4 0.0 0.025 13.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 EER25913.1 - 0.029 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.11 EER25913.1 - 0.032 13.2 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 EER25913.1 - 0.035 13.7 0.0 0.071 12.7 0.0 1.5 2 0 0 2 2 2 0 Nodulation protein S (NodS) MetW PF07021.12 EER25913.1 - 0.062 12.9 0.0 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pox_MCEL PF03291.16 EER25913.1 - 0.077 12.1 0.0 0.17 11.0 0.0 1.5 1 1 0 1 1 1 0 mRNA capping enzyme DUF647 PF04884.14 EER25913.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis M16C_assoc PF08367.11 EER25914.1 - 4.6e-72 242.2 0.1 6.4e-72 241.7 0.1 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EER25914.1 - 9.5e-23 81.2 0.0 1.7e-15 57.5 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EER25914.1 - 5.9e-11 42.5 0.0 6.5e-10 39.2 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.9 EER25915.1 - 1.1e-92 310.5 52.8 1.1e-92 310.5 52.8 1.4 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DUF4201 PF13870.6 EER25915.1 - 0.25 11.1 54.2 0.089 12.5 21.5 4.3 1 1 3 5 5 5 0 Domain of unknown function (DUF4201) TPR_MLP1_2 PF07926.12 EER25915.1 - 3.1 7.9 52.0 0.23 11.5 13.1 3.2 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 EER25915.1 - 3.5 6.9 45.0 0.18 11.1 8.5 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 EER25915.1 - 6.5 7.0 52.8 0.38 11.0 11.4 4.4 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3584 PF12128.8 EER25915.1 - 6.6 4.1 48.1 4.5 4.6 24.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF745 PF05335.13 EER25915.1 - 7.7 6.2 25.5 3.3 7.4 4.7 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF745) Leu_zip PF15294.6 EER25915.1 - 7.9 5.9 49.6 4.6 6.7 20.8 3.0 1 1 2 3 3 3 0 Leucine zipper DUF948 PF06103.11 EER25915.1 - 8.4 6.7 19.2 4.2 7.7 1.8 4.6 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 EER25915.1 - 8.6 6.1 60.9 0.046 13.5 18.8 3.5 1 1 2 3 3 3 0 Ezrin/radixin/moesin family BRE1 PF08647.11 EER25915.1 - 9.4 6.4 52.2 1.3 9.2 7.9 5.1 3 2 1 5 5 5 0 BRE1 E3 ubiquitin ligase NMO PF03060.15 EER25916.1 - 4.4e-53 180.8 0.1 5.9e-53 180.4 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EER25916.1 - 8.4e-07 28.3 0.0 1.2e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EER25916.1 - 6.2e-05 22.2 2.6 0.00013 21.2 2.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase PEP_hydrolase PF09370.10 EER25916.1 - 0.058 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like Glu_synthase PF01645.17 EER25916.1 - 0.27 10.3 2.2 0.56 9.3 2.2 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase Fungal_trans_2 PF11951.8 EER25917.1 - 2.4e-18 66.2 0.2 3.2e-18 65.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER25917.1 - 6.8e-08 32.5 10.3 1.6e-07 31.3 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 EER25918.1 - 1.8e-90 304.1 0.0 3.9e-90 303.0 0.0 1.5 1 1 0 1 1 1 1 Amidase M20_dimer PF07687.14 EER25919.1 - 0.00013 21.8 0.1 0.00034 20.5 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.16 EER25920.1 - 7.8e-38 130.3 32.5 7.8e-38 130.3 32.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EER25920.1 - 3.8e-06 26.4 6.9 3.8e-06 26.4 6.9 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4131 PF13567.6 EER25920.1 - 0.068 12.8 0.2 0.068 12.8 0.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) DNA_pol_E_B PF04042.16 EER25921.1 - 1.4e-44 152.0 0.0 1.8e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EER25921.1 - 3.9e-40 137.0 0.0 6.4e-40 136.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Proteasome PF00227.26 EER25922.1 - 1.3e-47 161.8 0.3 1.5e-47 161.6 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase_4 PF12146.8 EER25923.1 - 6.4e-16 58.3 0.0 5.7e-11 42.1 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EER25923.1 - 3e-08 33.6 0.0 6.5e-05 22.7 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 EER25923.1 - 5e-05 23.3 0.0 0.058 13.3 0.0 2.3 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EER25923.1 - 0.00014 21.4 0.0 0.00036 20.1 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EER25923.1 - 0.00019 21.2 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 EER25923.1 - 0.00019 20.5 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 EER25923.1 - 0.00061 19.4 0.0 0.77 9.3 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EER25923.1 - 0.0012 19.5 0.0 0.0019 18.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 EER25923.1 - 0.0048 15.6 0.0 0.55 8.8 0.0 2.3 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 EER25923.1 - 0.013 15.3 0.0 1.3 8.8 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EER25923.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EER25923.1 - 0.13 11.8 0.0 15 5.0 0.0 2.1 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase ATP11 PF06644.11 EER25924.1 - 3.6e-100 335.2 0.0 4.2e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Glyco_hydro_46 PF01374.18 EER25924.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 46 Tropomyosin_1 PF12718.7 EER25925.1 - 6.7e-19 68.5 27.1 6.7e-19 68.5 27.1 1.4 1 1 0 1 1 1 1 Tropomyosin like TMF_DNA_bd PF12329.8 EER25925.1 - 6.5e-06 26.0 8.5 6.5e-06 26.0 8.5 3.2 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding GAS PF13851.6 EER25925.1 - 1.8e-05 24.2 24.5 0.00095 18.6 11.5 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 EER25925.1 - 0.00015 21.2 26.4 0.023 14.0 4.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EER25925.1 - 0.00059 19.9 11.5 0.055 13.5 1.6 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EER25925.1 - 0.00082 18.8 22.7 0.0028 17.0 22.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 EER25925.1 - 0.0013 18.2 29.3 0.0015 17.9 29.3 1.1 1 0 0 1 1 1 1 Tropomyosin Alanine_zipper PF11839.8 EER25925.1 - 0.003 17.9 11.9 0.003 17.9 11.9 2.3 2 1 1 3 3 2 1 Alanine-zipper, major outer membrane lipoprotein EzrA PF06160.12 EER25925.1 - 0.0044 15.3 19.2 0.0092 14.2 2.5 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA bZIP_1 PF00170.21 EER25925.1 - 0.0068 16.5 0.7 0.0068 16.5 0.7 3.8 3 1 0 4 4 3 1 bZIP transcription factor Wtap PF17098.5 EER25925.1 - 0.0072 16.3 4.9 0.0072 16.3 4.9 2.6 1 1 1 2 2 2 1 WTAP/Mum2p family Uso1_p115_C PF04871.13 EER25925.1 - 0.009 16.4 30.9 0.32 11.4 17.5 2.1 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region WD40_alt PF14077.6 EER25925.1 - 0.0092 15.8 1.3 0.0092 15.8 1.3 2.5 3 1 1 4 4 2 1 Alternative WD40 repeat motif Lebercilin PF15619.6 EER25925.1 - 0.012 15.2 29.1 0.035 13.8 7.4 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease THOC7 PF05615.13 EER25925.1 - 0.015 15.6 22.6 1.2 9.4 10.1 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 HALZ PF02183.18 EER25925.1 - 0.018 15.2 2.1 0.018 15.2 2.1 3.6 4 0 0 4 4 3 0 Homeobox associated leucine zipper BLOC1_2 PF10046.9 EER25925.1 - 0.019 15.2 15.6 0.51 10.7 3.8 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Leu_zip PF15294.6 EER25925.1 - 0.021 14.4 19.4 0.061 12.8 19.4 1.7 1 1 0 1 1 1 0 Leucine zipper FapA PF03961.13 EER25925.1 - 0.025 13.2 21.3 0.079 11.5 5.1 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A AAA_13 PF13166.6 EER25925.1 - 0.029 13.0 17.7 0.039 12.6 17.7 1.2 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.12 EER25925.1 - 0.036 14.1 16.4 0.066 13.2 7.9 2.5 1 1 1 2 2 2 0 Laminin Domain II BRE1 PF08647.11 EER25925.1 - 0.04 14.0 27.7 0.091 12.8 3.2 3.1 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase CALCOCO1 PF07888.11 EER25925.1 - 0.079 11.8 24.8 0.61 8.9 11.9 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like HMMR_N PF15905.5 EER25925.1 - 0.085 12.3 23.9 0.084 12.3 12.7 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Seryl_tRNA_N PF02403.22 EER25925.1 - 0.13 12.5 26.4 0.32 11.3 10.6 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 EER25925.1 - 0.15 12.5 14.1 1.8 9.0 1.1 4.2 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Prefoldin_2 PF01920.20 EER25925.1 - 0.15 12.1 26.2 0.69 9.9 10.6 3.6 1 1 2 3 3 3 0 Prefoldin subunit ADIP PF11559.8 EER25925.1 - 0.15 12.1 26.9 0.075 13.1 4.8 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HalX PF08663.10 EER25925.1 - 0.16 12.3 19.9 1.6 9.1 0.3 4.5 1 1 2 4 4 4 0 HalX domain DUF1192 PF06698.11 EER25925.1 - 0.17 12.0 13.4 14 5.8 1.1 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1192) NPV_P10 PF05531.12 EER25925.1 - 0.17 12.4 10.0 1.9e+03 -0.6 10.0 3.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 EER25925.1 - 0.17 11.4 26.8 3.3 7.2 21.3 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain ATG16 PF08614.11 EER25925.1 - 0.23 11.6 28.8 4 7.6 18.1 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Lectin_N PF03954.14 EER25925.1 - 0.26 11.0 9.9 1.1 9.0 1.0 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain KASH_CCD PF14662.6 EER25925.1 - 0.29 11.0 28.1 0.059 13.2 8.9 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HBM PF16591.5 EER25925.1 - 0.31 10.4 17.8 0.91 8.9 15.6 1.9 1 1 1 2 2 2 0 Helical bimodular sensor domain Jnk-SapK_ap_N PF09744.9 EER25925.1 - 0.31 11.3 30.2 1.1 9.5 6.1 2.2 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 EER25925.1 - 0.32 11.4 25.6 0.38 11.2 6.4 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 EER25925.1 - 0.34 10.7 29.0 0.16 11.8 7.0 3.9 1 1 3 4 4 4 0 Septum formation initiator TPR_MLP1_2 PF07926.12 EER25925.1 - 0.36 10.9 32.7 2.1 8.4 11.0 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 EER25925.1 - 0.4 11.1 30.1 0.77 10.2 8.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 EER25925.1 - 0.42 11.1 18.7 1.4 9.5 4.8 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 CEP209_CC5 PF16574.5 EER25925.1 - 0.48 10.6 19.4 0.3 11.3 2.1 3.0 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 eIF3_N PF09440.10 EER25925.1 - 0.59 10.6 13.1 0.62 10.5 3.1 2.2 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain Spc7 PF08317.11 EER25925.1 - 0.71 8.7 26.2 0.62 8.9 16.6 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CLZ PF16526.5 EER25925.1 - 0.75 10.2 22.9 5.4 7.4 6.0 3.6 1 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mod_r PF07200.13 EER25925.1 - 0.75 9.9 26.4 1.1 9.3 4.0 2.3 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Phage_GP20 PF06810.11 EER25925.1 - 0.9 9.3 28.5 0.051 13.4 4.9 3.0 1 1 2 3 3 3 0 Phage minor structural protein GP20 CENP-F_leu_zip PF10473.9 EER25925.1 - 0.9 9.6 28.1 17 5.4 13.5 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.13 EER25925.1 - 0.96 8.6 16.5 0.91 8.7 2.4 2.0 1 1 1 2 2 2 0 TMPIT-like protein ERM PF00769.19 EER25925.1 - 1.1 9.0 32.8 53 3.5 32.9 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family JIP_LZII PF16471.5 EER25925.1 - 1.1 9.4 20.7 9 6.6 2.2 4.0 1 1 4 5 5 5 0 JNK-interacting protein leucine zipper II LPD39 PF18858.1 EER25925.1 - 1.1 9.2 16.3 20 5.2 16.3 2.4 1 1 0 1 1 1 0 Large polyvalent protein associated domain 39 DUF724 PF05266.14 EER25925.1 - 1.2 8.9 19.8 0.4 10.5 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 EER25925.1 - 1.2 9.9 15.0 16 6.3 7.0 2.9 1 1 1 2 2 2 0 Occludin homology domain Atg14 PF10186.9 EER25925.1 - 1.5 7.9 21.9 0.053 12.6 8.7 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EER25925.1 - 1.5 9.0 14.5 1.1 9.4 3.5 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 EER25925.1 - 1.6 9.1 22.7 1.8 9.0 12.2 2.0 1 1 0 1 1 1 0 Fez1 MPS2 PF17060.5 EER25925.1 - 1.7 7.8 16.6 2.2 7.5 3.3 2.7 1 1 1 2 2 2 0 Monopolar spindle protein 2 Phage_GPO PF05929.11 EER25925.1 - 1.8 8.1 20.5 2.2 7.9 8.5 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase APG6_N PF17675.1 EER25925.1 - 1.8 9.1 35.7 4 8.0 10.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 EER25925.1 - 1.8 9.2 20.0 1.2 9.8 3.6 3.0 1 1 2 3 3 3 0 Initiation control protein YabA T3SSipB PF16535.5 EER25925.1 - 1.8 9.0 22.0 0.8 10.2 10.8 2.3 1 1 1 2 2 2 0 Type III cell invasion protein SipB HAUS6_N PF14661.6 EER25925.1 - 1.9 8.0 19.8 0.39 10.3 8.9 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Baculo_PEP_C PF04513.12 EER25925.1 - 2.9 7.9 7.7 84 3.2 7.7 2.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 EER25925.1 - 3 8.2 25.5 0.31 11.4 5.2 2.7 1 1 0 2 2 2 0 YlqD protein LPP PF04728.13 EER25925.1 - 3 8.3 13.8 11 6.5 0.1 4.4 1 1 3 4 4 4 0 Lipoprotein leucine-zipper Fungal_TACC PF12709.7 EER25925.1 - 3 8.3 18.0 4.6 7.7 1.4 3.9 2 2 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins TPD52 PF04201.15 EER25925.1 - 3 7.4 15.9 0.064 12.9 3.4 2.7 1 1 2 3 3 3 0 Tumour protein D52 family Syntaxin-6_N PF09177.11 EER25925.1 - 3.4 8.3 14.5 2.3 8.8 4.6 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Hemerythrin PF01814.23 EER25925.1 - 3.4 8.3 10.9 96 3.6 4.5 3.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF2203 PF09969.9 EER25925.1 - 3.6 8.3 17.3 3.7 8.3 8.5 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1319 PF07028.11 EER25925.1 - 3.6 7.9 11.8 0.49 10.6 1.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Cnn_1N PF07989.11 EER25925.1 - 4.1 7.6 23.7 0.094 12.9 5.7 3.4 1 1 1 2 2 1 0 Centrosomin N-terminal motif 1 RecG_N PF17190.4 EER25925.1 - 5.9 7.7 10.3 5.4 7.8 1.0 2.9 2 1 1 3 3 3 0 RecG N-terminal helical domain CorA PF01544.18 EER25925.1 - 6.2 6.1 10.8 1.8 7.8 7.3 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein XhlA PF10779.9 EER25925.1 - 6.8 7.0 17.4 6.2 7.1 0.3 3.7 2 2 1 4 4 4 0 Haemolysin XhlA PspA_IM30 PF04012.12 EER25925.1 - 7.8 6.0 33.2 2.1 7.9 5.3 2.2 1 1 1 2 2 2 0 PspA/IM30 family DASH_Dad3 PF08656.10 EER25925.1 - 7.9 6.6 9.4 5.3 7.2 0.2 3.0 2 1 0 2 2 2 0 DASH complex subunit Dad3 Cep57_MT_bd PF06657.13 EER25925.1 - 8.2 7.0 17.3 1.1 9.8 1.9 2.8 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ApoO PF09769.9 EER25925.1 - 8.8 6.3 7.2 31 4.6 4.3 2.6 1 1 1 2 2 2 0 Apolipoprotein O Med9 PF07544.13 EER25925.1 - 9.5 6.4 18.0 0.37 10.9 3.1 3.5 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Golgin_A5 PF09787.9 EER25925.1 - 10 5.5 25.9 9.4 5.6 14.6 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 Nop25 PF09805.9 EER25926.1 - 6e-38 130.4 11.4 6e-38 130.4 11.4 2.6 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.12 EER25927.1 - 0.0002 21.2 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) BatA PF07584.11 EER25927.1 - 0.2 12.1 0.2 0.56 10.6 0.2 1.8 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Ank_2 PF12796.7 EER25928.1 - 1.3e-53 179.5 15.8 3.6e-13 49.9 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER25928.1 - 1.6e-39 133.8 7.8 4.6e-07 30.2 0.0 8.9 4 1 3 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER25928.1 - 7e-34 112.0 11.0 0.0017 18.7 0.0 12.5 13 0 0 13 13 13 7 Ankyrin repeat Ank PF00023.30 EER25928.1 - 2.8e-33 112.9 6.9 0.0025 18.2 0.0 11.9 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 EER25928.1 - 2.4e-31 107.4 14.1 1.1e-06 28.8 0.1 8.4 3 2 5 8 8 8 8 Ankyrin repeats (many copies) Glyco_hyd_101C PF17451.2 EER25928.1 - 0.06 13.6 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain HNH_2 PF13391.6 EER25929.1 - 9.6e-17 60.9 0.3 2.8e-16 59.4 0.3 1.8 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_3 PF00933.21 EER25930.1 - 1.6e-76 257.8 0.0 2.1e-76 257.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 EER25930.1 - 1.6e-20 73.4 0.1 7.1e-10 39.1 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER25930.1 - 1.6e-19 70.1 0.1 2.8e-08 34.1 0.0 3.7 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER25930.1 - 7.6e-18 64.7 0.0 5.5e-09 36.0 0.0 3.5 3 1 0 4 4 4 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER25930.1 - 9.3e-09 35.1 0.1 0.0012 18.8 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.7 EER25930.1 - 1.8e-05 24.8 0.0 0.19 11.8 0.0 2.7 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER25930.1 - 0.00011 22.3 0.1 0.019 15.1 0.0 2.8 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_6 PF13480.7 EER25930.1 - 0.00045 20.4 0.2 0.012 15.7 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EER25930.1 - 0.0044 16.7 0.1 0.027 14.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Glyco_hydro_3_C PF01915.22 EER25930.1 - 0.013 15.5 0.0 0.054 13.4 0.0 2.0 2 1 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_13 PF13880.6 EER25930.1 - 0.035 14.1 0.1 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Pyr_redox_2 PF07992.14 EER25931.1 - 1.6e-40 139.2 0.6 2.4e-40 138.6 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER25931.1 - 8.6e-12 45.5 0.6 2.2e-10 40.9 0.8 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EER25931.1 - 1.1e-07 31.9 4.8 0.003 17.2 0.1 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EER25931.1 - 5.9e-07 29.0 0.1 1.2e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER25931.1 - 3.4e-06 26.5 1.2 2.1e-05 23.8 0.1 2.5 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EER25931.1 - 2.2e-05 23.5 0.8 0.88 8.3 0.0 3.3 2 1 1 3 3 3 3 Tryptophan halogenase NAD_binding_9 PF13454.6 EER25931.1 - 2.3e-05 24.5 4.2 0.34 10.9 0.1 4.7 5 0 0 5 5 5 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EER25931.1 - 0.00026 20.1 0.5 0.065 12.3 0.1 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EER25931.1 - 0.0018 17.4 1.7 1.6 7.7 0.0 2.9 3 1 0 3 3 3 2 FAD binding domain Thi4 PF01946.17 EER25931.1 - 0.0067 15.7 0.5 0.63 9.2 0.0 2.5 2 1 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EER25931.1 - 0.012 15.8 0.1 11 6.3 0.0 3.1 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EER25931.1 - 0.025 13.3 2.1 0.48 9.1 0.4 3.2 4 0 0 4 4 4 0 HI0933-like protein DUF4147 PF13660.6 EER25931.1 - 0.043 13.4 0.2 0.25 10.8 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4147) Malic_M PF03949.15 EER25931.1 - 0.093 12.0 0.2 0.24 10.6 0.2 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain UPF0227 PF05728.12 EER25931.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GIDA PF01134.22 EER25931.1 - 0.13 11.3 9.3 0.88 8.6 0.4 4.2 4 1 1 5 5 5 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EER25931.1 - 9 5.5 7.9 45 3.2 3.0 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Acetyltransf_1 PF00583.25 EER25932.1 - 1.5e-07 31.6 0.0 2.9e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER25932.1 - 2.9e-07 30.8 0.0 5.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER25932.1 - 2.3e-06 27.5 0.0 6e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER25932.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2935 PF11155.8 EER25933.1 - 0.051 13.9 0.1 0.09 13.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) CMAS PF02353.20 EER25934.1 - 1.2e-59 201.9 0.0 1.5e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EER25934.1 - 1.4e-08 34.8 0.0 2.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER25934.1 - 3.3e-08 34.1 0.1 6.4e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER25934.1 - 5.8e-08 33.3 0.0 1.3e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EER25934.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_12 PF08242.12 EER25934.1 - 0.022 15.5 0.1 0.05 14.3 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EER25934.1 - 0.096 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EER25934.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EER25934.1 - 0.13 11.8 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.19 EER25934.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AMP-binding PF00501.28 EER25935.1 - 1.2e-97 327.2 0.0 1.4e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER25935.1 - 3.9e-14 53.4 0.1 9.1e-14 52.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box PF00646.33 EER25936.1 - 0.00041 20.2 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EER25936.1 - 0.043 13.7 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 F-box-like MCM PF00493.23 EER25937.1 - 7.7e-103 342.4 0.0 1.7e-102 341.3 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EER25937.1 - 2.3e-32 111.5 0.5 4.1e-32 110.7 0.5 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EER25937.1 - 2.4e-20 72.8 0.2 6.7e-20 71.3 0.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EER25937.1 - 2.1e-18 66.8 0.4 5.2e-18 65.5 0.4 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EER25937.1 - 6.1e-07 29.0 0.0 5.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EER25937.1 - 4.4e-06 26.7 0.0 1.2e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EER25937.1 - 0.017 15.0 0.0 0.054 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA lid domain Mg_chelatase_C PF13335.6 EER25937.1 - 0.026 15.2 0.2 0.23 12.1 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 EER25937.1 - 0.032 14.1 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TA0956 PF11513.8 EER25937.1 - 0.077 13.2 2.5 0.28 11.4 0.6 2.8 3 0 0 3 3 3 0 Thermoplasma acidophilum protein TA0956 AAA PF00004.29 EER25937.1 - 0.081 13.4 1.7 7.8 6.9 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EER25937.1 - 0.37 11.1 2.4 12 6.3 0.0 3.2 2 1 1 3 3 3 0 AAA ATPase domain AAA PF00004.29 EER25938.1 - 3.7e-54 182.7 0.0 3.6e-43 147.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EER25938.1 - 1.4e-29 102.3 0.2 3.8e-29 100.9 0.2 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EER25938.1 - 4.3e-16 58.5 0.2 2.6e-08 33.5 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EER25938.1 - 1.2e-08 35.6 1.1 0.0057 17.0 0.0 3.8 2 2 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EER25938.1 - 1.6e-06 28.4 0.0 0.11 12.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) NACHT PF05729.12 EER25938.1 - 2.6e-06 27.5 0.6 0.00091 19.2 0.0 3.1 3 0 0 3 3 3 1 NACHT domain RuvB_N PF05496.12 EER25938.1 - 0.00012 21.9 0.0 0.016 14.9 0.0 2.8 3 0 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EER25938.1 - 0.00016 22.0 2.5 1.2 9.4 0.3 3.9 2 2 1 3 3 3 2 AAA domain AAA_18 PF13238.6 EER25938.1 - 0.0002 21.9 0.4 0.61 10.6 0.3 3.3 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EER25938.1 - 0.00032 20.5 0.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EER25938.1 - 0.00035 20.6 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EER25938.1 - 0.00044 20.3 0.0 0.59 10.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE PEX-2N PF09263.10 EER25938.1 - 0.0025 18.1 0.2 2.2 8.6 0.1 2.7 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal TIP49 PF06068.13 EER25938.1 - 0.0052 16.0 0.1 1.9 7.6 0.0 2.5 3 0 0 3 3 3 1 TIP49 P-loop domain RNA_helicase PF00910.22 EER25938.1 - 0.0085 16.5 0.0 6.6 7.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase T2SSE PF00437.20 EER25938.1 - 0.012 14.7 0.0 0.03 13.4 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 EER25938.1 - 0.013 15.6 0.0 0.25 11.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 EER25938.1 - 0.016 14.6 0.1 2.1 7.6 0.0 2.4 2 0 0 2 2 2 0 KaiC Zeta_toxin PF06414.12 EER25938.1 - 0.022 14.0 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 EER25938.1 - 0.025 14.1 0.0 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EER25938.1 - 0.046 13.4 0.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EER25938.1 - 0.056 13.0 0.3 9.2 5.8 0.2 3.2 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 EER25938.1 - 0.063 13.8 0.0 14 6.2 0.0 2.7 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.6 EER25938.1 - 0.076 13.4 0.3 3.1 8.2 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EER25938.1 - 0.088 13.0 0.0 21 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EER25938.1 - 0.15 11.4 0.2 0.97 8.8 0.1 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DAP3 PF10236.9 EER25939.1 - 3.8e-93 312.1 0.0 4.7e-93 311.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RRS1 PF04939.12 EER25940.1 - 7.6e-57 191.7 1.4 9.3e-57 191.4 1.4 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) Ribosomal_L41 PF05162.13 EER25940.1 - 0.0064 16.5 5.1 0.0064 16.5 5.1 2.5 3 0 0 3 3 3 1 Ribosomal protein L41 DEC-1_N PF04625.13 EER25940.1 - 1.4 7.9 4.1 2.1 7.3 4.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region RhoGAP PF00620.27 EER25941.1 - 9e-29 100.3 0.0 1.5e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.21 EER25942.1 - 1.1e-56 188.2 5.3 6.5e-12 45.0 0.1 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EER25942.1 - 0.0002 20.6 0.0 0.23 10.5 0.0 2.6 2 1 0 2 2 2 2 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EER25942.1 - 0.00032 19.9 0.5 0.22 10.6 0.1 3.0 1 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain MutS_V PF00488.21 EER25944.1 - 6e-74 248.1 0.1 1.1e-73 247.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EER25944.1 - 2.3e-35 122.6 2.0 3e-35 122.2 0.6 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EER25944.1 - 3.8e-30 104.4 0.0 9.4e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EER25944.1 - 5.5e-08 33.2 0.0 2.8e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EER25944.1 - 0.0018 18.6 0.1 0.01 16.1 0.2 2.3 2 0 0 2 2 2 1 MutS family domain IV DUF4911 PF16256.5 EER25944.1 - 0.028 14.4 0.1 0.061 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) Ribosomal_S28e PF01200.18 EER25945.1 - 1.2e-32 111.7 0.6 1.3e-32 111.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e NiFeSe_Hases PF00374.19 EER25945.1 - 0.097 11.6 0.0 0.097 11.6 0.0 1.0 1 0 0 1 1 1 0 Nickel-dependent hydrogenase HisG PF01634.18 EER25946.1 - 1.6e-54 184.2 0.1 2.6e-54 183.5 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EER25946.1 - 6.6e-29 99.9 0.3 1.4e-28 98.8 0.3 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain DUF1949 PF09186.11 EER25947.1 - 0.062 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) PrpF PF04303.13 EER25948.1 - 4.8e-98 328.5 0.6 5.4e-98 328.4 0.6 1.0 1 0 0 1 1 1 1 PrpF protein Peptidase_C48 PF02902.19 EER25949.1 - 9.2e-15 55.1 0.0 4.4e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 EER25949.1 - 0.015 15.4 0.1 0.039 14.0 0.0 1.7 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) RhoGEF PF00621.20 EER25950.1 - 4.8e-36 124.7 0.1 1e-34 120.4 0.0 2.4 2 0 0 2 2 2 1 RhoGEF domain KMP11 PF03037.16 EER25950.1 - 0.21 12.4 0.8 1.1 10.2 0.8 2.2 1 0 0 1 1 1 0 Kinetoplastid membrane protein 11 Telomerase_RBD PF12009.8 EER25951.1 - 3e-47 160.1 0.0 6.8e-47 158.9 0.0 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EER25951.1 - 1.1e-11 44.7 0.0 2.7e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.18 EER25952.1 - 1.7e-26 93.2 0.0 2.7e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EER25952.1 - 1.8e-07 29.8 1.0 5.1e-07 28.3 1.4 1.5 2 0 0 2 2 2 1 SBE2, cell-wall formation Cyclin PF08613.11 EER25953.1 - 1.2e-34 120.1 8.7 1.6e-23 83.8 0.1 3.1 3 1 0 3 3 3 2 Cyclin Bunya_G1 PF03557.15 EER25953.1 - 0.3 9.0 0.0 0.39 8.6 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 Mucin PF01456.17 EER25954.1 - 0.0081 16.2 10.4 0.0081 16.2 10.4 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein nos_propeller PF18764.1 EER25954.1 - 0.046 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat EXS PF03124.14 EER25955.1 - 3.7e-90 302.6 4.7 4.2e-90 302.4 4.7 1.1 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 EER25956.1 - 3.7e-45 154.3 3.5 4.8e-45 153.9 3.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 EER25956.1 - 6.4e-11 42.4 10.6 1.1e-10 41.7 10.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER25956.1 - 6.6e-11 41.9 9.5 1.1e-10 41.2 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER25956.1 - 1.4e-10 40.9 7.5 2.3e-10 40.2 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER25956.1 - 1.9e-10 40.5 5.8 3.2e-10 39.7 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER25956.1 - 2.8e-08 33.6 9.2 6e-08 32.6 9.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EER25956.1 - 2.1e-07 30.7 6.6 3.5e-07 30.0 6.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EER25956.1 - 3.7e-07 30.3 7.2 8.8e-07 29.1 7.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EER25956.1 - 4e-07 29.9 6.6 6.7e-07 29.2 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EER25956.1 - 1.6e-05 24.9 9.2 3e-05 24.1 9.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EER25956.1 - 0.0016 18.5 5.4 0.0029 17.7 5.4 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EER25956.1 - 0.0055 16.7 1.5 0.011 15.7 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EER25956.1 - 0.0061 16.3 4.3 0.012 15.4 4.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 EER25956.1 - 0.044 13.7 3.0 0.079 12.8 3.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Transposase_23 PF03017.14 EER25956.1 - 0.11 12.5 1.1 0.13 12.2 0.0 1.6 2 0 0 2 2 1 0 TNP1/EN/SPM transposase zf-RING_4 PF14570.6 EER25956.1 - 0.17 11.7 7.9 0.4 10.5 7.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EER25956.1 - 0.36 10.6 4.4 1.1 9.1 4.4 1.9 1 0 0 1 1 1 0 RING-like zinc finger FYVE PF01363.21 EER25956.1 - 0.77 9.9 5.4 2.5 8.3 5.4 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 EER25956.1 - 5.7 7.3 7.9 17 5.7 7.9 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain AA_permease PF00324.21 EER25957.1 - 2.4e-139 465.0 40.3 3.5e-139 464.5 40.3 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER25957.1 - 1.5e-32 113.0 42.1 2e-32 112.6 42.1 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EER25957.1 - 0.29 9.9 4.5 0.055 12.3 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) RhoGAP PF00620.27 EER25958.1 - 3.6e-15 56.1 0.0 9.6e-15 54.7 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 EER25958.1 - 2e-11 43.8 0.0 4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EER25958.1 - 1.6e-08 34.7 0.0 5.3e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Phage_TAC_8 PF10666.9 EER25958.1 - 0.088 13.1 2.4 0.16 12.3 0.5 2.2 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Gp14 ()A118 AAA_16 PF13191.6 EER25959.1 - 2.2e-14 54.2 0.8 2e-13 51.1 0.3 2.6 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EER25959.1 - 4e-14 53.1 0.0 8.1e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EER25959.1 - 8.7e-14 52.1 0.0 1.6e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 EER25959.1 - 7.4e-09 35.5 0.0 2.3e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_5 PF07728.14 EER25959.1 - 0.00014 21.9 0.0 0.00045 20.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) TniB PF05621.11 EER25959.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 EER25959.1 - 0.00077 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_10 PF17872.1 EER25959.1 - 0.00097 19.2 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain PIF1 PF05970.14 EER25959.1 - 0.00099 18.4 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 EER25959.1 - 0.0011 19.3 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EER25959.1 - 0.0036 17.7 0.0 0.0066 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase T2SSE PF00437.20 EER25959.1 - 0.0055 15.8 0.0 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein TIP49 PF06068.13 EER25959.1 - 0.01 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_11 PF13086.6 EER25959.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EER25959.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 EER25959.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EER25959.1 - 0.017 15.3 0.0 0.058 13.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activat PF00158.26 EER25959.1 - 0.017 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EER25959.1 - 0.021 15.4 0.0 0.058 13.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 EER25959.1 - 0.028 14.2 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EER25959.1 - 0.056 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.9 EER25959.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EER25959.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA12 PF10443.9 EER25959.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein AAA_14 PF13173.6 EER25959.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EER25959.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EER25959.1 - 0.15 11.9 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_18 PF13238.6 EER25959.1 - 0.18 12.4 0.0 0.32 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EER25959.1 - 0.2 11.4 0.0 0.73 9.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 EER25959.1 - 0.2 10.8 0.0 0.32 10.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Thioredoxin_7 PF13899.6 EER25960.1 - 5.4e-16 58.5 0.0 1.2e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EER25960.1 - 5.7e-13 48.5 0.1 1.1e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EER25960.1 - 3e-06 27.3 0.0 1.1e-05 25.6 0.0 2.0 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 EER25960.1 - 0.079 13.4 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like domain CBP_CCPA PF17040.5 EER25960.1 - 0.095 13.3 1.3 1.1 9.8 0.1 3.1 3 1 1 4 4 4 0 Cellulose-complementing protein A Pkinase PF00069.25 EER25961.1 - 1.5e-68 231.0 0.0 2.1e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25961.1 - 1.2e-50 172.2 0.0 1.8e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER25961.1 - 2.2e-06 26.7 0.2 6.5e-06 25.2 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EER25961.1 - 0.14 11.4 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 EER25962.1 - 1.5e-54 185.1 0.0 2.2e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25962.1 - 8.1e-23 81.0 0.0 1.2e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EER25962.1 - 3.6e-17 62.5 0.0 6.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EER25962.1 - 2.3e-08 34.2 0.0 5.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EER25962.1 - 3.3e-08 33.2 0.0 6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EER25962.1 - 0.014 14.4 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CorA PF01544.18 EER25963.1 - 0.1 11.9 0.1 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein ADH_N PF08240.12 EER25964.1 - 2.7e-25 88.3 1.7 5.2e-25 87.4 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER25964.1 - 5.9e-22 78.0 0.2 9.2e-22 77.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER25964.1 - 2.8e-05 25.2 0.0 5.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EER25964.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glu_dehyd_C PF16912.5 EER25964.1 - 0.038 13.5 0.2 0.072 12.6 0.2 1.5 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus NADH_4Fe-4S PF10589.9 EER25964.1 - 2.7 8.1 6.1 5.4 7.2 4.5 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SWIM PF04434.17 EER25965.1 - 0.003 17.2 0.2 0.0051 16.4 0.2 1.4 1 0 0 1 1 1 1 SWIM zinc finger RecC_C PF17946.1 EER25965.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain AurF PF11583.8 EER25965.1 - 0.17 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF SET PF00856.28 EER25966.1 - 2.2e-09 38.0 0.0 2.3e-07 31.3 0.0 3.1 2 1 0 2 2 2 1 SET domain SAP PF02037.27 EER25966.1 - 0.00049 19.8 1.6 0.0011 18.6 0.3 2.2 2 0 0 2 2 2 1 SAP domain TPR_9 PF13371.6 EER25966.1 - 0.0089 16.2 0.3 0.038 14.1 0.1 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Nup35_RRM_2 PF14605.6 EER25966.1 - 0.18 11.8 0.1 0.9 9.6 0.1 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif zf-H2C2_2 PF13465.6 EER25968.1 - 9.3e-12 44.8 16.0 2.3e-06 27.8 1.9 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EER25968.1 - 1.3e-07 31.7 29.8 0.0055 17.1 8.1 4.0 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER25968.1 - 2.8e-05 24.6 24.9 0.052 14.4 6.5 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EER25968.1 - 3.8e-05 23.6 18.5 0.0067 16.4 0.0 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 EER25968.1 - 0.0057 16.7 6.4 0.009 16.1 1.9 2.5 2 0 0 2 2 2 1 Zinc ribbon domain Rad50_zn_hook PF04423.14 EER25968.1 - 0.0071 16.2 2.4 0.12 12.3 0.4 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Di19 PF05605.12 EER25968.1 - 0.017 15.4 10.5 0.023 15.0 6.7 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 EER25968.1 - 0.078 12.8 4.9 2.2 8.2 0.3 3.8 3 1 1 4 4 4 0 C2H2 type zinc-finger (1 copy) DZR PF12773.7 EER25968.1 - 0.11 12.6 6.9 1.1 9.3 6.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon DUF1192 PF06698.11 EER25968.1 - 0.17 11.9 0.2 0.89 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) zf-C2HE PF16278.5 EER25968.1 - 0.22 12.0 15.1 0.4 11.2 1.1 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 EER25968.1 - 0.25 11.3 6.9 0.061 13.2 1.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc_ribbon_9 PF14369.6 EER25968.1 - 0.3 11.4 3.2 33 4.9 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon zf-CHCC PF10276.9 EER25968.1 - 0.34 11.0 7.0 1.2 9.3 0.2 2.9 3 0 0 3 3 2 0 Zinc-finger domain DUF3268 PF11672.8 EER25968.1 - 0.48 10.7 2.5 0.38 11.1 0.7 1.7 1 1 0 1 1 1 0 zinc-finger-containing domain HypA PF01155.19 EER25968.1 - 0.74 9.8 3.1 2.3 8.3 3.1 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-BED PF02892.15 EER25968.1 - 1.1 9.3 9.0 3.9 7.6 5.3 3.2 2 1 1 3 3 3 0 BED zinc finger zf-FPG_IleRS PF06827.14 EER25968.1 - 1.9 8.5 6.6 1.9 8.4 0.7 2.8 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zinc-ribbons_6 PF07191.12 EER25968.1 - 2 8.5 5.3 7.2 6.7 5.3 1.9 1 1 0 1 1 1 0 zinc-ribbons zf-C2H2_jaz PF12171.8 EER25968.1 - 4.5 7.7 12.9 2.3 8.6 2.4 3.6 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 EER25968.1 - 4.9 7.0 10.5 3.6 7.4 1.5 3.0 1 1 2 3 3 3 0 GAGA factor Zn_Tnp_IS1595 PF12760.7 EER25968.1 - 5.1 7.1 9.4 30 4.7 0.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_2 PF12756.7 EER25968.1 - 6.2 7.2 11.4 2.6 8.4 1.6 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 EER25968.1 - 6.9 7.4 14.6 1.2 9.9 1.0 3.9 2 2 1 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF3074 PF11274.8 EER25969.1 - 5.7e-36 124.2 0.0 1.1e-35 123.3 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) Methyltransf_2 PF00891.18 EER25969.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Stk19 PF10494.9 EER25970.1 - 3.3e-90 302.0 0.0 4e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.21 EER25971.1 - 1.7e-148 495.2 0.0 2.3e-105 353.0 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EER25971.1 - 3.5e-39 134.3 0.0 5.6e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 EER25971.1 - 0.035 13.8 0.3 0.067 12.9 0.3 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain 4HBT_3 PF13622.6 EER25972.1 - 5.5e-41 141.5 0.2 6.3e-41 141.3 0.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EER25973.1 - 9.8e-05 22.6 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TIL PF01826.17 EER25975.1 - 0.96 9.7 10.8 0.081 13.2 5.5 1.9 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain PCI PF01399.27 EER25976.1 - 4.2e-12 46.5 0.1 1.2e-11 45.1 0.0 1.8 2 0 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 EER25976.1 - 9.6e-11 41.2 3.0 9.6e-11 41.2 3.0 2.2 2 0 0 2 2 2 1 eIF3 subunit M, C-terminal helix Mo25 PF08569.11 EER25976.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Mo25-like Ribosomal_S14 PF00253.21 EER25977.1 - 2.4e-15 56.0 4.3 2.6e-15 55.9 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.6 EER25977.1 - 0.061 13.3 0.5 0.08 12.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) ADK PF00406.22 EER25978.1 - 9.6e-41 139.4 0.0 2.8e-40 137.9 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EER25978.1 - 2.2e-33 115.6 0.0 2.9e-33 115.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EER25978.1 - 2.7e-10 40.9 0.0 3.6e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EER25978.1 - 3.4e-05 24.0 0.0 0.0022 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EER25978.1 - 0.00027 20.6 0.0 0.0027 17.4 0.0 2.1 1 1 0 1 1 1 1 Thymidylate kinase Ploopntkinase3 PF18751.1 EER25978.1 - 0.034 14.0 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MARVEL PF01284.23 EER25979.1 - 0.0032 17.5 7.5 0.0032 17.5 7.5 1.8 1 1 0 2 2 2 1 Membrane-associating domain DUF1218 PF06749.12 EER25979.1 - 0.066 13.7 1.3 0.19 12.2 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) DUF2746 PF10874.8 EER25979.1 - 0.1 13.0 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) COX1 PF00115.20 EER25979.1 - 0.14 11.0 4.3 0.19 10.5 4.3 1.2 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I Cnd2 PF05786.14 EER25980.1 - 0 1033.9 0.1 0 1033.7 0.1 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EER25980.1 - 0.0017 18.5 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal FAM176 PF14851.6 EER25980.1 - 0.067 12.8 1.8 0.2 11.3 1.8 1.8 1 0 0 1 1 1 0 FAM176 family DUF4611 PF15387.6 EER25980.1 - 6 7.2 7.7 0.28 11.4 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Na_Ca_ex PF01699.24 EER25981.1 - 1.4e-51 174.4 49.0 9.4e-29 100.3 19.3 3.5 4 0 0 4 4 4 2 Sodium/calcium exchanger protein EF-hand_4 PF12763.7 EER25982.1 - 7.8e-24 83.6 0.0 8.2e-13 48.2 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 EER25982.1 - 1.4e-09 37.5 0.8 4.1e-09 36.0 0.8 1.8 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 EER25982.1 - 4.2e-08 33.5 110.0 1.4e-05 25.4 30.3 7.9 5 2 2 7 7 7 4 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EER25982.1 - 0.033 13.7 0.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EER25982.1 - 0.092 13.2 8.4 0.31 11.5 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain pair RNA_pol_L_2 PF13656.6 EER25983.1 - 4.4e-27 93.6 0.0 6.6e-27 93.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EER25983.1 - 5.5e-12 44.9 0.0 9.3e-12 44.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NMO PF03060.15 EER25984.1 - 7.7e-36 124.1 1.0 1.1e-27 97.3 0.3 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EER25984.1 - 5.2e-10 38.9 3.2 7.5e-10 38.3 3.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EER25984.1 - 1.6e-08 34.0 0.2 3.2e-07 29.7 0.2 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EER25984.1 - 2.5e-05 23.6 1.7 4.3e-05 22.8 1.7 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase MRC1 PF09444.10 EER25985.1 - 0.47 11.0 14.6 0.39 11.2 8.9 2.4 2 0 0 2 2 2 0 MRC1-like domain UBN_AB PF14075.6 EER25985.1 - 0.73 9.5 9.2 1.6 8.4 9.2 1.5 1 0 0 1 1 1 0 Ubinuclein conserved middle domain FAM176 PF14851.6 EER25985.1 - 2 8.1 10.4 2.5 7.7 7.3 2.3 2 0 0 2 2 2 0 FAM176 family RPN2_C PF18004.1 EER25985.1 - 4.3 7.2 12.8 11 5.8 12.8 1.7 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain CDC45 PF02724.14 EER25985.1 - 4.4 5.5 10.0 7.1 4.8 10.0 1.2 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EER25985.1 - 8.9 6.8 16.5 21 5.5 7.8 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LRR_4 PF12799.7 EER25986.1 - 0.0054 17.1 11.9 6.3 7.4 0.6 5.7 3 2 5 8 8 8 3 Leucine Rich repeats (2 copies) TFIIF_alpha PF05793.12 EER25986.1 - 0.0082 14.8 8.8 0.012 14.3 8.8 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4604 PF15377.6 EER25986.1 - 0.019 15.4 10.2 0.028 14.9 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) FXR_C1 PF16096.5 EER25986.1 - 0.03 14.5 1.8 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 CDC45 PF02724.14 EER25986.1 - 1 7.5 7.5 1.6 6.9 7.5 1.2 1 0 0 1 1 1 0 CDC45-like protein FYVE PF01363.21 EER25986.1 - 1.7 8.9 5.7 0.47 10.6 1.5 2.3 2 1 0 2 2 2 0 FYVE zinc finger PRP1_N PF06424.12 EER25986.1 - 3.7 7.9 11.0 0.21 12.0 5.1 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal RR_TM4-6 PF06459.12 EER25986.1 - 9.3 6.0 11.5 0.72 9.6 6.2 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 SNF2_N PF00176.23 EER25987.1 - 4.6e-53 180.2 0.5 8.7e-52 176.0 0.0 2.7 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER25987.1 - 4.1e-17 62.5 0.5 6.9e-16 58.6 0.0 2.9 4 0 0 4 4 3 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EER25987.1 - 2.5e-07 30.4 7.8 2.5e-07 30.4 7.8 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EER25987.1 - 1.5e-05 25.1 0.0 8.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 EER25987.1 - 0.00017 21.4 7.3 0.00017 21.4 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER25987.1 - 0.00073 19.8 8.2 0.00073 19.8 8.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER25987.1 - 0.0015 18.4 6.2 0.0015 18.4 6.2 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EER25987.1 - 0.0021 17.0 0.0 0.0064 15.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 GRASP55_65 PF04495.14 EER25987.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Spt5_N PF11942.8 EER25987.1 - 0.73 10.9 10.4 6 7.9 1.2 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Zn_Tnp_IS91 PF14319.6 EER25987.1 - 1.7 8.7 17.2 0.11 12.6 5.2 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain PGA2 PF07543.12 EER25987.1 - 1.8 8.5 11.3 2.2 8.3 2.4 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Pkinase PF00069.25 EER25989.1 - 2.2e-29 102.7 0.0 1.3e-27 96.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25989.1 - 6e-08 32.3 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER25989.1 - 0.17 10.7 0.0 0.21 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EER25990.1 - 1.2e-10 41.8 0.0 1.3e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER25990.1 - 3.6e-05 23.5 0.0 4.7e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EER25990.1 - 0.0055 16.3 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 RIO1 family SBP_bac_3 PF00497.20 EER25990.1 - 0.022 14.2 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 C2 PF00168.30 EER25991.1 - 3.5e-14 53.0 0.0 6.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF3530 PF12048.8 EER25991.1 - 0.042 13.3 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Spc7 PF08317.11 EER25991.1 - 0.12 11.2 1.3 0.17 10.7 1.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-K PF11802.8 EER25991.1 - 0.24 10.9 3.5 7.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Centromere-associated protein K ArfGap PF01412.18 EER25992.1 - 5e-34 116.9 0.1 5e-34 116.9 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EER25992.1 - 4.7e-20 72.3 15.5 8.4e-20 71.5 15.5 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EER25992.1 - 2e-11 44.3 2.2 5.5e-11 42.9 0.2 2.7 3 0 0 3 3 3 1 PH domain EMP24_GP25L PF01105.24 EER25992.1 - 0.019 14.9 3.4 0.21 11.5 2.4 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Virul_Fac PF10139.9 EER25993.1 - 0.011 14.0 1.0 0.014 13.7 1.0 1.0 1 0 0 1 1 1 0 Putative bacterial virulence factor CLN3 PF02487.17 EER25993.1 - 0.047 12.7 0.4 0.08 12.0 0.4 1.3 1 0 0 1 1 1 0 CLN3 protein DUF4820 PF16091.5 EER25993.1 - 0.41 10.0 3.9 0.33 10.3 2.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) RNA_pol_Rpc4 PF05132.14 EER25993.1 - 0.65 10.4 4.8 1 9.8 4.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 PI3_PI4_kinase PF00454.27 EER25995.1 - 6.9e-37 127.6 0.0 1.1e-27 97.4 0.0 2.8 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EER25995.1 - 3.2e-22 78.8 0.0 8e-22 77.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Cut8 PF08559.10 EER25995.1 - 0.018 14.6 0.0 0.083 12.5 0.0 2.2 1 0 0 1 1 1 0 Cut8, nuclear proteasome tether protein Mtr2 PF10429.9 EER25995.1 - 0.082 12.8 0.0 16 5.4 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 Pkinase PF00069.25 EER25996.1 - 9.5e-76 254.6 0.0 1.3e-75 254.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25996.1 - 2.5e-36 125.3 0.0 3.3e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EER25996.1 - 7.8e-17 61.4 0.2 1.8e-16 60.3 0.2 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EER25996.1 - 7.9e-08 31.9 0.0 5.7e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 EER25996.1 - 1.4e-07 31.7 0.0 3.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 EER25996.1 - 9.3e-07 28.0 0.0 1.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EER25996.1 - 0.002 17.5 0.3 0.0037 16.6 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER25996.1 - 0.015 15.2 0.4 0.055 13.4 0.4 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EER25996.1 - 0.016 14.8 0.2 1.8 8.1 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EER25996.1 - 0.031 13.8 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 EER25996.1 - 0.22 10.4 0.0 0.33 9.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.22 EER25997.1 - 2.9e-66 224.1 0.0 3.6e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 IGR PF09597.10 EER25998.1 - 1.9e-24 85.5 0.6 3.7e-24 84.6 0.6 1.5 1 0 0 1 1 1 1 IGR protein motif SAM_1 PF00536.30 EER25998.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pkinase PF00069.25 EER25999.1 - 2.2e-60 204.3 0.0 2.6e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER25999.1 - 1.3e-31 109.9 0.0 2e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EER25999.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EER25999.1 - 0.025 13.9 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EER25999.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Syja_N PF02383.18 EER26000.1 - 1.1e-73 248.4 0.0 2e-73 247.5 0.0 1.4 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 EER26000.1 - 6.2e-09 35.7 0.0 1.1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EER26000.1 - 0.068 13.0 0.0 0.5 10.2 0.0 2.5 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Lge1 PF11488.8 EER26000.1 - 0.16 12.2 1.0 0.31 11.2 0.3 1.8 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF2258 PF10015.9 EER26001.1 - 0.28 11.4 1.9 0.91 9.7 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) SR-25 PF10500.9 EER26002.1 - 0.071 12.7 20.2 0.1 12.2 20.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RR_TM4-6 PF06459.12 EER26002.1 - 8.7 6.1 11.4 12 5.6 11.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EER26002.1 - 9.7 4.8 12.4 12 4.5 12.4 1.1 1 0 0 1 1 1 0 Presenilin TonB_2 PF13103.6 EER26003.1 - 0.16 12.2 0.4 1.3 9.3 0.0 2.4 3 0 0 3 3 3 0 TonB C terminal DAGAT PF03982.13 EER26004.1 - 5.6e-91 304.5 0.0 7.2e-91 304.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.13 EER26004.1 - 0.049 13.4 2.4 0.083 12.6 2.4 1.2 1 0 0 1 1 1 0 Rer1 family Glyco_transf_11 PF01531.16 EER26005.1 - 0.16 11.1 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Kinesin PF00225.23 EER26006.1 - 3e-96 322.3 0.1 5.8e-96 321.3 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EER26006.1 - 6.4e-24 84.6 0.0 4.8e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding PEPcase PF00311.17 EER26006.1 - 0.0063 14.7 0.9 0.0095 14.1 0.9 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PKcGMP_CC PF16808.5 EER26006.1 - 0.028 14.2 6.8 0.21 11.5 0.8 3.6 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FlxA PF14282.6 EER26006.1 - 0.081 12.9 4.3 10 6.2 2.1 3.0 2 0 0 2 2 2 0 FlxA-like protein DUF4407 PF14362.6 EER26006.1 - 0.66 9.3 13.1 0.14 11.5 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM76 PF16046.5 EER26006.1 - 1.4 8.2 5.8 23 4.2 0.1 2.8 2 1 0 2 2 2 0 FAM76 protein Adaptin_N PF01602.20 EER26007.1 - 2.4e-74 250.8 0.0 7.6e-74 249.1 0.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EER26007.1 - 2.5e-06 27.6 0.2 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EER26007.1 - 0.0016 18.5 1.6 5.9 7.4 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.6 EER26007.1 - 0.0025 18.2 3.1 1.3 9.4 0.6 3.4 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EER26007.1 - 0.0028 18.1 4.6 0.15 12.6 0.1 4.2 4 0 0 4 4 4 1 HEAT-like repeat AP3D1 PF06375.11 EER26007.1 - 0.052 13.8 0.2 0.052 13.8 0.2 2.8 2 1 1 3 3 3 0 AP-3 complex subunit delta-1 RTT107_BRCT_6 PF16771.5 EER26007.1 - 0.31 11.2 1.4 1.5 9.0 0.0 2.4 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain TPR_14 PF13428.6 EER26008.1 - 1.4e-05 25.5 5.6 0.16 12.9 0.1 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EER26008.1 - 0.00096 19.4 1.4 0.031 14.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EER26008.1 - 0.0031 17.5 0.1 0.0031 17.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EER26008.1 - 0.0039 17.3 0.2 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF627 PF04781.12 EER26008.1 - 0.014 15.4 0.2 0.049 13.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_16 PF13432.6 EER26008.1 - 0.031 14.9 5.1 0.087 13.5 0.1 3.5 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EER26008.1 - 0.04 14.4 3.4 0.071 13.6 0.1 2.9 3 2 1 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER26008.1 - 0.063 13.6 1.8 2 8.8 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EER26008.1 - 0.074 12.8 1.3 3.9 7.3 0.0 3.3 2 1 1 3 3 3 0 TPR repeat TPR_1 PF00515.28 EER26008.1 - 0.086 12.7 0.1 0.086 12.7 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EER26008.1 - 0.36 11.0 2.0 3.8 7.8 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat IF-2B PF01008.17 EER26009.1 - 2.3e-73 246.9 2.1 2.9e-73 246.5 2.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family APH PF01636.23 EER26011.1 - 8.1e-17 61.9 0.0 1.5e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER26011.1 - 0.00017 21.2 0.0 0.00027 20.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EER26011.1 - 0.0015 18.0 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EER26011.1 - 0.0038 16.8 0.0 0.096 12.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Pkinase_Tyr PF07714.17 EER26011.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase AP3D1 PF06375.11 EER26013.1 - 4.5e-06 27.0 10.8 4.6e-06 27.0 10.8 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 SR-25 PF10500.9 EER26013.1 - 7.1e-05 22.5 15.8 0.0001 22.0 15.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EER26013.1 - 8.6e-05 22.1 11.3 0.00011 21.7 11.3 1.1 1 0 0 1 1 1 1 BUD22 PPL5 PF18168.1 EER26013.1 - 0.00013 21.4 2.6 0.00013 21.4 2.6 1.1 1 0 0 1 1 1 1 Prim-pol family 5 Coilin_N PF15862.5 EER26013.1 - 0.00043 20.1 9.6 0.00043 20.1 9.6 1.2 1 0 0 1 1 1 1 Coilin N-terminus GAGA_bind PF06217.12 EER26013.1 - 0.00073 19.9 6.2 0.00073 19.9 6.2 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family Peptidase_S49_N PF08496.10 EER26013.1 - 0.004 17.2 6.7 0.0048 17.0 6.7 1.3 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Presenilin PF01080.17 EER26013.1 - 0.017 13.9 5.4 0.02 13.7 5.4 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EER26013.1 - 0.025 14.3 6.5 0.041 13.6 6.5 1.3 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 EER26013.1 - 0.027 13.2 0.8 0.031 13.0 0.8 1.1 1 0 0 1 1 1 0 Reduced folate carrier Pox_Ag35 PF03286.14 EER26013.1 - 0.028 14.2 15.3 0.038 13.8 15.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.13 EER26013.1 - 0.032 13.0 9.5 0.034 12.9 9.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 U1snRNP70_N PF12220.8 EER26013.1 - 0.05 14.2 11.1 0.075 13.7 11.1 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SspB PF04386.13 EER26013.1 - 0.064 13.2 6.7 0.079 12.8 6.7 1.1 1 0 0 1 1 1 0 Stringent starvation protein B SID-1_RNA_chan PF13965.6 EER26013.1 - 0.069 11.6 1.2 0.073 11.5 1.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TFB6 PF17110.5 EER26013.1 - 0.082 12.6 3.3 0.11 12.3 3.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RNA_pol_Rpc4 PF05132.14 EER26013.1 - 0.1 13.0 7.7 0.13 12.7 7.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Serinc PF03348.15 EER26013.1 - 0.11 11.5 1.4 0.12 11.3 1.4 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Vfa1 PF08432.10 EER26013.1 - 0.23 11.8 18.5 0.29 11.4 18.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 EER26013.1 - 0.24 11.5 7.0 0.38 10.9 7.0 1.3 1 0 0 1 1 1 0 DDHD domain CPSF100_C PF13299.6 EER26013.1 - 0.25 11.5 10.2 0.32 11.2 10.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 EER26013.1 - 0.31 8.9 6.3 0.32 8.9 6.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FancD2 PF14631.6 EER26013.1 - 0.32 8.3 7.4 0.34 8.3 7.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RMI1_N PF08585.12 EER26013.1 - 0.51 10.1 9.6 0.74 9.5 9.6 1.2 1 1 0 1 1 1 0 RecQ mediated genome instability protein Rtf2 PF04641.12 EER26013.1 - 0.58 9.5 16.9 0.71 9.2 16.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF1168 PF06658.12 EER26013.1 - 0.84 9.5 27.6 1.2 9.0 27.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Afi1 PF07792.12 EER26013.1 - 1.2 9.7 12.3 1.6 9.2 12.3 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NARP1 PF12569.8 EER26013.1 - 1.7 7.4 20.6 2.3 7.1 20.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2076 PF09849.9 EER26013.1 - 1.8 8.5 7.9 2.3 8.2 7.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PBP1_TM PF14812.6 EER26013.1 - 2.2 8.7 16.9 3.4 8.1 16.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Eapp_C PF10238.9 EER26013.1 - 2.9 7.9 12.2 4.4 7.4 12.2 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Cellulose_synt PF03552.14 EER26013.1 - 4.8 5.5 8.7 5.5 5.3 8.7 1.1 1 0 0 1 1 1 0 Cellulose synthase Peroxin-13_N PF04088.13 EER26013.1 - 5.9 7.2 6.5 8.9 6.6 6.5 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region AIF_C PF14721.6 EER26013.1 - 6.4 7.2 9.6 8.4 6.8 9.6 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term CLN3 PF02487.17 EER26013.1 - 6.4 5.7 7.4 8.5 5.3 7.1 1.3 1 1 0 1 1 1 0 CLN3 protein HMG14_17 PF01101.18 EER26013.1 - 8.4 7.4 29.1 13 6.8 29.1 1.2 1 0 0 1 1 1 0 HMG14 and HMG17 EIIBC-GUT_N PF03612.14 EER26013.1 - 9.8 5.9 9.8 14 5.4 9.8 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DEAD PF00270.29 EER26014.1 - 3.8e-48 163.6 0.0 7.7e-48 162.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26014.1 - 7.8e-31 106.7 0.0 6.1e-29 100.6 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER26014.1 - 3.4e-07 30.4 0.0 9.6e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EER26014.1 - 0.0077 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 EER26014.1 - 0.029 13.2 0.1 2.3 6.9 0.0 2.4 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF677 PF05055.12 EER26014.1 - 0.041 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Rft-1 PF04506.13 EER26015.1 - 2.8e-129 432.2 10.3 3.7e-129 431.8 10.3 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 EER26015.1 - 0.13 11.4 15.9 0.02 14.1 7.4 3.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein Rep_fac-A_C PF08646.10 EER26016.1 - 2.5e-47 160.3 2.4 2.2e-45 154.0 1.1 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EER26016.1 - 1.8e-33 114.4 0.0 4.4e-33 113.1 0.0 1.7 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EER26016.1 - 1.9e-22 79.2 0.0 8.5e-22 77.1 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EER26016.1 - 1.6e-11 44.0 0.0 1.9e-08 34.2 0.0 3.6 3 1 0 3 3 3 1 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EER26016.1 - 0.0016 18.2 0.3 0.048 13.4 0.7 2.9 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 DUF3383 PF11863.8 EER26016.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) UDG PF03167.19 EER26017.1 - 5.2e-24 85.0 0.1 8.8e-24 84.2 0.1 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2673 PF10880.8 EER26017.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DNA_pol_E_B PF04042.16 EER26018.1 - 1.7e-47 161.5 0.0 2.5e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Med14 PF08638.11 EER26019.1 - 4.8e-58 195.7 0.1 1.3e-57 194.4 0.0 1.8 2 0 0 2 2 2 1 Mediator complex subunit MED14 DWNN PF08783.11 EER26020.1 - 5.3e-34 116.3 0.1 9.6e-34 115.5 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EER26020.1 - 1.2e-08 34.6 5.8 2.3e-08 33.7 5.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EER26020.1 - 0.0019 18.2 0.8 0.0038 17.2 0.8 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-RING_2 PF13639.6 EER26020.1 - 0.18 12.2 6.3 0.45 10.9 6.3 1.7 1 0 0 1 1 1 0 Ring finger domain zf-Nse PF11789.8 EER26020.1 - 0.19 11.6 3.3 0.46 10.3 3.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EER26020.1 - 0.38 10.6 6.3 1 9.2 6.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE_2 PF02318.16 EER26020.1 - 0.81 9.9 3.2 0.78 10.0 1.3 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-RING_5 PF14634.6 EER26020.1 - 2.3 8.3 11.7 0.18 11.8 5.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EER26020.1 - 5.4 7.3 8.7 16 5.8 8.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Oxidored_q6 PF01058.22 EER26021.1 - 4e-22 78.4 0.0 6.5e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit NifU_N PF01592.16 EER26023.1 - 7.5e-52 174.8 0.0 1e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EER26023.1 - 0.048 13.9 0.0 0.091 13.0 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain Aldedh PF00171.22 EER26024.1 - 4.8e-11 41.8 2.6 4.9e-08 31.9 0.8 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L18 PF17135.4 EER26025.1 - 4e-93 310.0 4.6 4.5e-93 309.9 4.6 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EER26025.1 - 4.6e-05 24.1 0.4 4.6e-05 24.1 0.4 1.9 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Sedlin_N PF04628.13 EER26026.1 - 1.2e-11 44.9 0.0 1.4e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EER26026.1 - 0.11 12.4 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 Sybindin-like family RRM_1 PF00076.22 EER26027.1 - 5.9e-12 45.2 0.0 8.1e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EER26027.1 - 0.00077 19.4 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 EER26028.1 - 5.7e-76 250.6 0.7 2.1e-24 85.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EER26028.1 - 0.00013 21.2 0.2 0.0036 16.5 0.0 2.7 2 1 1 3 3 3 1 Gammaproteobacterial serine protease PXA PF02194.15 EER26029.1 - 8.8e-31 107.3 0.1 1.9e-30 106.2 0.1 1.6 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EER26029.1 - 1e-21 77.6 0.2 8.7e-21 74.6 0.0 2.6 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.24 EER26029.1 - 8.2e-12 45.1 0.1 3.7e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 PX domain PRELI PF04707.14 EER26031.1 - 8.4e-45 152.4 0.1 9.8e-45 152.2 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.14 EER26031.1 - 0.051 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CTP_transf_like PF01467.26 EER26032.1 - 1.3e-24 87.0 0.0 6.5e-21 75.0 0.0 3.3 2 1 1 4 4 4 2 Cytidylyltransferase-like Glutaredoxin PF00462.24 EER26033.1 - 4.7e-16 58.8 0.0 9.2e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.19 EER26034.1 - 1e-43 148.8 0.0 1.5e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Flavoprotein UbiA PF01040.18 EER26035.1 - 1.4e-40 139.2 22.3 1.8e-40 138.9 22.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-4CXXC_R1 PF10497.9 EER26036.1 - 2.4e-09 37.3 7.5 2.4e-09 37.3 7.5 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.22 EER26036.1 - 4.7e-08 33.5 2.5 3e-07 30.9 0.6 2.9 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EER26036.1 - 0.0077 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Coa1 PF08695.10 EER26038.1 - 9.3e-37 125.3 0.0 1.8e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TssO PF17561.2 EER26038.1 - 0.97 9.5 0.0 0.97 9.5 0.0 3.0 2 1 1 3 3 3 0 Type VI secretion system, TssO Ribosomal_L3 PF00297.22 EER26039.1 - 1e-16 60.9 5.6 4.7e-14 52.2 5.6 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 DUF1176 PF06674.11 EER26039.1 - 0.25 10.8 0.0 0.36 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) DUF1279 PF06916.13 EER26040.1 - 3.6e-23 81.9 0.0 5.6e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ank_2 PF12796.7 EER26041.1 - 3.5e-36 123.6 0.3 3.7e-12 46.7 0.0 4.0 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER26041.1 - 1.9e-30 104.8 4.7 4.8e-13 49.3 0.0 6.3 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER26041.1 - 2e-20 70.7 5.3 0.0032 17.8 0.0 7.7 8 0 0 8 8 8 5 Ankyrin repeat SPX PF03105.19 EER26041.1 - 2.9e-20 73.5 10.3 1.9e-08 34.6 0.4 3.2 1 1 2 3 3 3 3 SPX domain GDPD PF03009.17 EER26041.1 - 9.4e-14 51.8 0.0 4.1e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_5 PF13857.6 EER26041.1 - 1.1e-13 51.1 1.8 0.00064 20.0 0.0 5.9 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EER26041.1 - 3.4e-11 43.1 5.4 0.018 15.5 0.0 6.8 7 0 0 7 7 7 3 Ankyrin repeat SKG6 PF08693.10 EER26042.1 - 1.5e-10 40.3 7.0 2.7e-10 39.5 7.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EER26042.1 - 0.0018 18.1 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Phage_holin_2_4 PF16082.5 EER26042.1 - 0.045 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like SIT PF15330.6 EER26042.1 - 0.18 12.3 0.1 0.45 11.0 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Peptidase_M56 PF05569.11 EER26042.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 CcmD PF04995.14 EER26042.1 - 0.29 11.3 0.6 0.45 10.7 0.6 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2615 PF11027.8 EER26042.1 - 5.8 7.1 0.0 5.8 7.1 0.0 4.2 2 1 2 4 4 4 0 Protein of unknown function (DUF2615) MFS_1 PF07690.16 EER26044.1 - 1.3e-38 132.9 41.1 1.3e-38 132.9 41.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER26045.1 - 6.4e-103 345.0 14.0 6.1e-80 269.3 4.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EER26045.1 - 1.2e-24 86.9 35.3 1.6e-13 50.3 7.0 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 EER26045.1 - 0.00026 19.6 1.3 0.00026 19.6 1.3 2.1 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EER26045.1 - 0.055 12.3 0.1 0.055 12.3 0.1 2.5 3 0 0 3 3 3 0 MFS_1 like family LacY_symp PF01306.19 EER26045.1 - 0.074 11.8 7.5 0.2 10.4 0.1 2.7 3 0 0 3 3 3 0 LacY proton/sugar symporter ABC_tran PF00005.27 EER26046.1 - 2.4e-47 160.9 0.3 1.6e-22 80.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EER26046.1 - 1.3e-20 73.2 5.6 1.3e-20 73.2 5.6 2.9 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EER26046.1 - 6.4e-18 65.6 2.2 0.0014 18.5 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EER26046.1 - 5.3e-11 42.4 0.3 0.012 15.1 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EER26046.1 - 9.9e-07 29.1 0.0 0.0064 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EER26046.1 - 2.4e-06 28.0 0.3 0.049 14.0 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EER26046.1 - 2.9e-06 27.4 0.0 0.048 13.8 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER26046.1 - 6.1e-06 26.2 1.6 0.056 13.3 0.1 3.0 2 1 0 3 3 3 2 RsgA GTPase AAA_23 PF13476.6 EER26046.1 - 1e-05 26.2 16.6 0.014 15.9 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 EER26046.1 - 1.2e-05 25.0 0.2 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 EER26046.1 - 2.8e-05 23.9 0.1 0.0039 16.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EER26046.1 - 4e-05 23.4 1.3 0.35 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EER26046.1 - 9.3e-05 23.0 4.5 0.29 11.7 0.0 3.4 5 0 0 5 5 3 2 AAA domain AAA_15 PF13175.6 EER26046.1 - 0.00011 22.0 12.1 0.15 11.7 0.0 5.1 4 1 0 4 4 4 2 AAA ATPase domain AAA_28 PF13521.6 EER26046.1 - 0.00017 21.9 1.9 0.23 11.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EER26046.1 - 0.00017 21.7 4.2 0.15 12.2 0.2 3.2 3 1 0 3 3 2 2 AAA domain AAA PF00004.29 EER26046.1 - 0.0012 19.3 0.0 0.96 9.9 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EER26046.1 - 0.0018 17.9 0.5 3.4 7.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 EER26046.1 - 0.0019 18.2 0.1 0.85 9.5 0.0 2.7 3 0 0 3 3 2 1 NACHT domain Zeta_toxin PF06414.12 EER26046.1 - 0.003 16.9 1.7 3.5 6.9 0.1 3.4 3 0 0 3 3 3 1 Zeta toxin Dynamin_N PF00350.23 EER26046.1 - 0.0033 17.5 4.2 2.5 8.2 0.0 3.9 4 0 0 4 4 4 1 Dynamin family MeaB PF03308.16 EER26046.1 - 0.0071 15.4 1.4 2.8 6.8 0.0 2.7 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EER26046.1 - 0.008 16.2 0.0 7.5 6.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EER26046.1 - 0.0092 16.4 0.0 5 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 EER26046.1 - 0.012 15.5 0.4 1.3 8.9 0.0 3.1 2 1 1 3 3 3 0 Rad17 P-loop domain NTPase_1 PF03266.15 EER26046.1 - 0.03 14.2 0.0 2.7 7.9 0.0 2.8 2 0 0 2 2 2 0 NTPase Roc PF08477.13 EER26046.1 - 0.037 14.2 0.1 7.6 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 EER26046.1 - 0.041 13.9 0.5 9.4 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EER26046.1 - 0.046 13.2 0.0 6.1 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 EER26046.1 - 0.056 13.1 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.22 EER26046.1 - 0.066 12.8 0.0 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 EER26046.1 - 0.068 12.4 0.1 11 5.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.14 EER26046.1 - 0.082 12.8 0.0 2.4 8.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 EER26046.1 - 0.088 12.8 0.0 19 5.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EER26046.1 - 0.097 12.3 2.7 1.8 8.1 0.3 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 EER26046.1 - 1.2 8.8 3.8 2.3 7.9 0.0 2.9 3 1 1 4 4 3 0 Phosphoribulokinase / Uridine kinase family WD40 PF00400.32 EER26048.1 - 3.7e-24 84.5 25.9 2.1e-05 25.2 0.2 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER26048.1 - 1.8e-10 41.0 8.1 0.00038 20.7 0.3 4.4 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EER26048.1 - 0.0001 22.3 8.9 0.04 13.8 0.2 2.6 1 1 1 2 2 2 2 Transcription factor IIIC subunit delta N-term BHD_1 PF10403.9 EER26049.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 SNF5 PF04855.12 EER26051.1 - 1.5e-76 257.4 0.0 2.1e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EER26051.1 - 0.0025 17.4 0.1 0.0083 15.7 0.1 1.9 1 0 0 1 1 1 1 GATA zinc finger Glug PF07581.12 EER26051.1 - 0.059 13.8 11.9 0.15 12.6 1.3 2.4 2 0 0 2 2 2 0 The GLUG motif AA_permease PF00324.21 EER26053.1 - 4.3e-100 335.6 29.5 5.2e-100 335.3 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER26053.1 - 4.1e-21 75.3 28.6 5.4e-21 74.9 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.11 EER26053.1 - 0.00083 19.7 1.9 0.00083 19.7 1.9 3.6 2 1 3 5 5 5 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.18 EER26054.1 - 6.5e-18 64.7 0.0 1.3e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26054.1 - 1.6e-07 31.3 10.5 2.8e-07 30.5 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF948 PF06103.11 EER26054.1 - 0.24 11.7 1.2 4.8 7.5 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Cupin_8 PF13621.6 EER26055.1 - 1.6e-22 80.5 0.0 2.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EER26055.1 - 0.0027 18.1 0.0 0.0071 16.8 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EER26055.1 - 0.11 12.2 0.0 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.12 EER26055.1 - 0.16 11.4 0.0 0.33 10.4 0.0 1.4 2 0 0 2 2 2 0 Cupin superfamily protein CK_II_beta PF01214.18 EER26056.1 - 1.5e-77 259.5 0.0 4.7e-77 257.9 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit bZIP_2 PF07716.15 EER26057.1 - 0.00065 19.7 8.1 0.0013 18.8 8.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EER26057.1 - 0.0012 18.9 8.9 0.0019 18.2 8.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EER26057.1 - 0.0018 18.7 2.3 0.0033 17.9 2.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Aminotran_4 PF01063.19 EER26058.1 - 2.4e-38 132.2 0.0 4.4e-38 131.4 0.0 1.4 2 0 0 2 2 2 1 Amino-transferase class IV Pkinase PF00069.25 EER26059.1 - 4.9e-16 58.9 0.0 2.1e-15 56.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26059.1 - 4.5e-08 32.7 0.0 2.5e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.9 EER26059.1 - 0.057 13.5 0.3 0.55 10.3 0.1 2.2 2 0 0 2 2 2 0 Parkin co-regulated protein Peptidase_M49 PF03571.15 EER26060.1 - 2.1e-247 821.9 0.0 2.5e-247 821.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Cyt-b5 PF00173.28 EER26061.1 - 4.4e-08 33.2 0.0 5.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 EER26062.1 - 1.8e-60 200.7 0.0 8.1e-19 67.2 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EER26062.1 - 1.6e-06 28.5 0.4 0.71 10.1 0.0 6.2 4 3 3 7 7 7 1 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 EER26062.1 - 0.00022 20.8 0.0 0.25 10.9 0.0 2.4 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER26062.1 - 0.0018 18.4 0.0 6.2 7.0 0.0 3.9 4 0 0 4 4 4 1 RNA recognition motif RRM_Rrp7 PF17799.1 EER26062.1 - 0.0036 17.1 0.1 4.5 7.0 0.0 3.3 2 2 2 4 4 4 2 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EER26062.1 - 0.14 12.0 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Rad10 PF03834.14 EER26063.1 - 3.9e-46 155.8 0.0 5.9e-46 155.2 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EER26063.1 - 0.00083 19.9 0.0 0.0018 18.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EER26063.1 - 0.011 15.5 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fungal_trans_2 PF11951.8 EER26064.1 - 1.3e-11 44.0 0.0 7e-11 41.5 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Lyase_1 PF00206.20 EER26065.1 - 4.8e-20 72.2 0.0 8.9e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EER26065.1 - 8.1e-18 64.7 0.0 2.7e-17 63.1 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Fungal_trans PF04082.18 EER26066.1 - 1.1e-14 54.2 4.0 3.6e-14 52.5 2.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EER26066.1 - 0.0024 16.7 0.4 0.012 14.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tmemb_cc2 PF10267.9 EER26066.1 - 0.045 12.9 0.3 0.08 12.1 0.3 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein CHD5 PF04420.14 EER26067.1 - 4.3e-61 205.4 1.3 5.4e-61 205.1 1.3 1.1 1 0 0 1 1 1 1 CHD5-like protein YnfE PF17452.2 EER26067.1 - 0.082 13.2 0.1 0.13 12.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized YnfE-like PPTA PF01239.22 EER26068.1 - 0.00022 20.8 3.3 0.075 12.8 0.8 3.8 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat 4F5 PF04419.14 EER26069.1 - 8.6e-11 42.5 14.0 8.6e-11 42.5 14.0 2.3 2 1 0 2 2 2 1 4F5 protein family DFRP_C PF16543.5 EER26069.1 - 0.16 12.5 7.3 0.22 12.0 7.3 1.3 1 0 0 1 1 1 0 DRG Family Regulatory Proteins, Tma46 CDPS PF16715.5 EER26069.1 - 0.66 9.6 6.2 0.73 9.4 6.2 1.1 1 0 0 1 1 1 0 Cyclodipeptide synthase Neurensin PF14927.6 EER26070.1 - 0.00012 21.8 0.7 0.00012 21.8 0.7 2.6 1 1 1 2 2 2 1 Neurensin DUF3093 PF11292.8 EER26070.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) AA_permease_2 PF13520.6 EER26072.1 - 1.2e-51 175.9 45.0 1.6e-51 175.5 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER26072.1 - 1.7e-27 96.2 41.0 5.1e-27 94.6 40.9 1.6 1 1 0 1 1 1 1 Amino acid permease TRAM_LAG1_CLN8 PF03798.16 EER26074.1 - 9.2e-45 152.8 24.8 9.2e-45 152.8 24.8 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EER26074.1 - 3e-15 55.6 0.1 3e-15 55.6 0.1 2.5 3 0 0 3 3 3 1 TRAM1-like protein RRM_1 PF00076.22 EER26075.1 - 7e-14 51.4 0.0 1.8e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EER26075.1 - 0.0042 17.1 0.1 0.01 15.8 0.1 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SMN PF06003.12 EER26076.1 - 3.9e-06 26.3 4.7 8.2e-05 22.0 1.0 2.2 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) CAP_N PF01213.19 EER26077.1 - 0.27 10.7 5.3 0.38 10.2 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Thiolase_N PF00108.23 EER26078.1 - 1.2e-14 54.3 0.1 8.3e-14 51.6 0.1 2.2 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EER26078.1 - 1.2e-10 41.0 0.2 9.1e-10 38.3 0.2 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EER26078.1 - 7.3e-07 29.0 0.1 4.6e-05 23.2 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EER26078.1 - 0.0024 17.5 1.0 0.0051 16.4 1.0 1.6 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EER26078.1 - 0.025 13.3 0.1 0.055 12.2 0.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Mito_carr PF00153.27 EER26079.1 - 5.8e-40 135.1 7.5 3.3e-15 55.8 0.2 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein BRO1 PF03097.18 EER26080.1 - 3.3e-121 404.8 0.0 7.2e-121 403.6 0.0 1.6 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EER26080.1 - 4.8e-85 285.4 15.7 4.8e-85 285.4 15.7 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Siah-Interact_N PF09032.11 EER26080.1 - 9 6.7 8.8 8.1 6.8 0.1 3.7 3 0 0 3 3 3 0 Siah interacting protein, N terminal bZIP_2 PF07716.15 EER26081.1 - 3.7e-13 49.3 13.7 8.5e-13 48.2 13.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EER26081.1 - 2.7e-05 24.2 11.3 4.8e-05 23.4 11.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.18 EER26081.1 - 0.055 13.8 0.4 0.12 12.7 0.4 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Phlebovirus_NSM PF07246.11 EER26081.1 - 0.15 11.5 2.7 0.24 10.8 2.7 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CENP-N PF05238.13 EER26082.1 - 1.7e-121 406.4 1.6 3.8e-121 405.3 1.6 1.5 1 1 0 1 1 1 1 Kinetochore protein CHL4 like Filament_head PF04732.14 EER26082.1 - 0.0042 17.9 2.4 0.015 16.1 2.4 2.1 1 0 0 1 1 1 1 Intermediate filament head (DNA binding) region DUF974 PF06159.13 EER26083.1 - 2e-78 263.6 0.0 2.4e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.21 EER26084.1 - 1.7e-59 200.9 0.2 3.1e-59 200.1 0.2 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EER26084.1 - 4.9e-15 56.0 0.0 1.3e-14 54.7 0.0 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EER26084.1 - 2.5e-13 49.8 0.2 6.3e-13 48.5 0.2 1.7 1 0 0 1 1 1 1 dDENN domain C1_2 PF03107.16 EER26084.1 - 5.8e-07 29.7 4.0 1.2e-06 28.7 4.0 1.6 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 EER26084.1 - 0.0025 17.6 10.1 0.005 16.7 10.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 EER26084.1 - 0.12 12.3 7.6 0.091 12.7 5.5 1.9 1 1 1 2 2 2 0 PHD-finger Zf_RING PF16744.5 EER26084.1 - 0.69 10.1 6.6 1.9 8.7 6.4 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger PHD_2 PF13831.6 EER26084.1 - 1.4 8.6 4.6 0.5 10.0 0.7 2.1 2 0 0 2 2 2 0 PHD-finger zf-HIT PF04438.16 EER26084.1 - 3.8 7.5 6.1 8.5 6.4 6.1 1.6 1 1 0 1 1 1 0 HIT zinc finger FtsX PF02687.21 EER26085.1 - 0.17 12.4 6.9 1.2 9.7 6.9 2.0 1 1 0 1 1 1 0 FtsX-like permease family RasGEF PF00617.19 EER26086.1 - 1.3e-52 178.6 0.6 2.4e-52 177.7 0.6 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EER26086.1 - 4.5e-15 55.8 0.0 3e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.6 EER26086.1 - 6.1e-06 26.0 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EER26086.1 - 0.00018 21.1 0.0 0.00072 19.1 0.0 2.1 3 0 0 3 3 3 1 SH3 domain FMO-like PF00743.19 EER26087.1 - 9.8e-11 40.8 0.4 1.9e-09 36.5 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.24 EER26087.1 - 5e-08 32.9 0.0 0.0046 16.6 0.0 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER26087.1 - 7.9e-08 31.9 0.0 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER26087.1 - 3.2e-07 30.5 0.0 8.4e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EER26087.1 - 5.6e-06 25.8 0.0 0.00082 18.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER26087.1 - 6e-05 22.4 0.0 0.022 13.9 0.0 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EER26087.1 - 0.008 15.4 0.0 0.098 11.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 EER26087.1 - 0.035 13.4 0.0 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EER26087.1 - 0.037 14.0 0.3 0.2 11.6 0.0 2.4 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EER26087.1 - 0.077 13.6 0.1 0.93 10.1 0.0 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF2209 PF09974.9 EER26088.1 - 0.083 13.2 0.0 0.32 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) RcnB PF11776.8 EER26088.1 - 0.11 12.6 2.0 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Nickel/cobalt transporter regulator Cut8 PF08559.10 EER26089.1 - 7.6e-82 274.5 0.0 9.1e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein rRNA_proc-arch PF13234.6 EER26090.1 - 6.6e-83 278.7 0.1 1.3e-82 277.7 0.1 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EER26090.1 - 6.8e-55 185.2 1.7 2e-54 183.7 1.7 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EER26090.1 - 1.6e-18 67.1 0.0 3.6e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26090.1 - 1.2e-06 28.9 0.0 4e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER26090.1 - 7.4e-05 22.8 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EER26090.1 - 0.077 12.0 0.0 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein COX7C PF02935.16 EER26091.1 - 1.1e-21 76.8 7.1 1.3e-21 76.6 7.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.12 EER26092.1 - 0 1022.5 0.0 0 1022.1 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EER26092.1 - 0.0053 17.0 0.2 15 6.0 0.0 4.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain NurA PF09376.10 EER26092.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 NurA domain MDD_C PF18376.1 EER26093.1 - 1.1e-65 220.8 0.0 1.7e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EER26093.1 - 1.7e-09 37.8 0.9 3.8e-09 36.6 0.9 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain HCMV_UL124 PF17609.2 EER26093.1 - 0.12 12.6 0.7 0.55 10.4 0.5 2.1 2 0 0 2 2 2 0 Family of unknown function Cyto_heme_lyase PF01265.17 EER26094.1 - 2.6e-43 148.7 6.9 4.6e-36 124.9 0.0 2.4 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase Syntaxin_2 PF14523.6 EER26095.1 - 3.4e-26 91.6 2.0 3.4e-26 91.6 2.0 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EER26095.1 - 3.1e-15 55.9 2.3 3.4e-15 55.8 0.9 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EER26095.1 - 5.3e-06 26.2 9.1 9.2e-06 25.5 9.1 1.5 1 0 0 1 1 1 1 Syntaxin DUF883 PF05957.13 EER26095.1 - 0.015 15.9 12.4 0.44 11.2 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Synaptobrevin PF00957.21 EER26095.1 - 0.021 14.6 1.8 0.022 14.6 0.1 2.1 2 0 0 2 2 2 0 Synaptobrevin MPS2 PF17060.5 EER26095.1 - 0.022 14.0 5.1 0.019 14.3 3.0 1.8 1 1 1 2 2 2 0 Monopolar spindle protein 2 Prominin PF05478.11 EER26095.1 - 0.063 11.2 4.1 0.15 10.0 4.0 1.7 1 1 0 1 1 1 0 Prominin T3SSipB PF16535.5 EER26095.1 - 0.51 10.8 16.0 0.17 12.3 10.9 2.3 2 1 1 3 3 3 0 Type III cell invasion protein SipB DUF16 PF01519.16 EER26095.1 - 1.9 9.0 8.5 26 5.4 5.7 3.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Ndc1_Nup PF09531.10 EER26096.1 - 1.7e-199 664.5 2.5 1.9e-199 664.3 2.5 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup NUDIX PF00293.28 EER26097.1 - 3.5e-08 33.6 0.1 0.00079 19.5 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain DSPc PF00782.20 EER26098.1 - 1.5e-25 89.5 0.0 2.1e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EER26098.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EER26098.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-C2H2_jaz PF12171.8 EER26099.1 - 1.5e-05 25.1 7.2 0.00088 19.5 4.1 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EER26099.1 - 0.0022 18.3 0.7 0.0022 18.3 0.7 3.0 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EER26099.1 - 0.004 17.5 2.0 0.004 17.5 2.0 3.7 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-met PF12874.7 EER26099.1 - 0.018 15.4 1.4 0.018 15.4 1.4 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-FCS PF06467.14 EER26099.1 - 0.034 14.1 2.7 2.9 7.9 0.4 2.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_4 PF13894.6 EER26099.1 - 0.76 10.8 15.5 0.19 12.7 2.3 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-MYST PF17772.1 EER26099.1 - 0.77 9.4 7.8 1.4 8.6 0.9 2.5 1 1 1 2 2 2 0 MYST family zinc finger domain zf-CHCC PF10276.9 EER26099.1 - 1.2 9.3 3.9 4.8 7.3 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger domain Vfa1 PF08432.10 EER26100.1 - 1.7e-60 204.4 15.1 1.9e-60 204.3 15.1 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 RR_TM4-6 PF06459.12 EER26100.1 - 0.0013 18.7 12.1 0.0018 18.2 12.1 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 DUF4746 PF15928.5 EER26100.1 - 0.0072 15.8 9.3 0.0082 15.6 9.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) Coilin_N PF15862.5 EER26100.1 - 0.011 15.5 10.2 0.015 15.1 10.2 1.5 1 0 0 1 1 1 0 Coilin N-terminus DUF2347 PF09804.9 EER26100.1 - 0.011 15.3 0.8 0.015 14.9 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) NPR3 PF03666.13 EER26100.1 - 0.022 13.6 9.1 0.024 13.5 9.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 EER26100.1 - 0.061 12.6 8.6 0.071 12.4 8.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DDHD PF02862.17 EER26100.1 - 0.14 12.3 3.4 0.17 12.0 3.4 1.1 1 0 0 1 1 1 0 DDHD domain RNA_pol_Rpc4 PF05132.14 EER26100.1 - 0.15 12.5 9.0 0.23 11.9 9.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 NPAT_C PF15712.5 EER26100.1 - 0.28 9.8 8.9 0.3 9.7 8.9 1.1 1 0 0 1 1 1 0 NPAT C terminus CDC45 PF02724.14 EER26100.1 - 0.3 9.3 12.6 0.32 9.2 12.6 1.0 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 EER26100.1 - 0.34 9.9 8.0 0.37 9.8 8.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2828 PF11443.8 EER26100.1 - 0.39 8.7 9.2 0.39 8.8 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PA26 PF04636.13 EER26100.1 - 0.41 9.5 4.3 0.45 9.4 4.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) ATP11 PF06644.11 EER26100.1 - 0.43 10.3 14.1 0.52 10.0 14.1 1.1 1 0 0 1 1 1 0 ATP11 protein DUF913 PF06025.12 EER26100.1 - 0.44 9.5 4.4 0.52 9.2 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Neur_chan_memb PF02932.16 EER26100.1 - 0.88 9.6 3.0 0.91 9.5 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4775 PF16001.5 EER26100.1 - 1.2 8.4 24.1 1.4 8.3 24.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Zip PF02535.22 EER26100.1 - 1.7 7.8 5.8 1.9 7.7 5.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF908 PF06012.12 EER26100.1 - 1.7 7.9 3.8 2.2 7.6 3.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF4407 PF14362.6 EER26100.1 - 1.8 7.8 7.5 2.1 7.6 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 EER26100.1 - 2.1 7.0 10.1 2.6 6.7 10.1 1.1 1 0 0 1 1 1 0 Presenilin GCD14 PF08704.10 EER26100.1 - 3.3 7.3 5.9 5.7 6.5 5.9 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Connexin PF00029.19 EER26100.1 - 3.5 7.3 11.1 5.3 6.7 11.1 1.4 1 0 0 1 1 1 0 Connexin Sec62 PF03839.16 EER26100.1 - 3.7 7.0 14.2 4.7 6.7 14.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2252 PF10009.9 EER26100.1 - 3.9 6.4 9.2 5.4 6.0 9.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF4820 PF16091.5 EER26100.1 - 4.4 6.6 10.4 0.39 10.1 5.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) GNAT_acetyltr_2 PF13718.6 EER26100.1 - 4.5 6.6 9.9 6.9 6.0 9.9 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 AAA_11 PF13086.6 EER26100.1 - 4.6 7.0 13.0 6.6 6.4 13.0 1.2 1 0 0 1 1 1 0 AAA domain ALMT PF11744.8 EER26100.1 - 4.9 5.9 8.3 5.8 5.6 8.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter HSP70 PF00012.20 EER26100.1 - 5.4 5.1 14.0 6.1 4.9 14.0 1.0 1 0 0 1 1 1 0 Hsp70 protein MCM_bind PF09739.9 EER26100.1 - 5.7 5.3 11.5 7.4 4.9 11.5 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor TP53IP5 PF15331.6 EER26100.1 - 6 7.0 14.0 8.2 6.5 14.0 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Asp PF00026.23 EER26102.1 - 6.5e-65 219.6 0.1 7.7e-65 219.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EER26102.1 - 1.6e-09 38.3 0.1 4.2e-06 27.1 0.0 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EER26102.1 - 0.0014 19.1 0.0 0.98 10.0 0.0 2.9 2 1 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EER26102.1 - 0.0027 18.3 0.0 3.5 8.3 0.0 2.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EER26102.1 - 0.016 15.0 0.0 0.09 12.6 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal SAP PF02037.27 EER26103.1 - 4.3e-11 42.3 0.0 7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain APH PF01636.23 EER26104.1 - 7.8e-10 39.1 0.0 2.8e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EER26104.1 - 0.094 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Mac PF12464.8 EER26105.1 - 0.14 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Maltose acetyltransferase FMN_dh PF01070.18 EER26106.1 - 1.2e-111 373.2 0.0 1.4e-111 372.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EER26106.1 - 5.7e-17 61.6 0.0 1.1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EER26106.1 - 0.00028 20.2 0.0 0.00042 19.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 EER26106.1 - 0.003 16.9 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 EER26106.1 - 0.033 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EER26106.1 - 0.051 13.0 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase TatD_DNase PF01026.21 EER26107.1 - 2.2e-48 164.9 0.0 2.6e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Y_phosphatase2 PF03162.13 EER26108.1 - 4.7e-45 153.1 0.1 6.4e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EER26108.1 - 3.2e-09 37.1 0.0 4.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EER26108.1 - 1.2e-06 28.3 0.1 1.8e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EER26108.1 - 0.00014 21.5 0.1 0.00039 20.1 0.1 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Aa_trans PF01490.18 EER26110.1 - 3.7e-76 256.5 31.1 4.3e-76 256.2 31.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Rad52_Rad22 PF04098.15 EER26112.1 - 2.7e-59 199.5 0.0 3.7e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBX PF00789.20 EER26113.1 - 1.6e-06 28.2 0.0 4.8e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 EER26113.1 - 0.0042 17.0 0.0 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Utp11 PF03998.13 EER26113.1 - 0.0098 15.9 19.5 0.013 15.4 19.5 1.2 1 0 0 1 1 1 1 Utp11 protein zf-C2H2_2 PF12756.7 EER26113.1 - 0.085 13.2 1.3 0.12 12.8 0.4 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EER26113.1 - 0.2 12.1 0.3 0.34 11.4 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type V_ATPase_I PF01496.19 EER26113.1 - 3.7 5.3 7.7 4 5.2 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CDC45 PF02724.14 EER26113.1 - 5.6 5.1 18.8 7.2 4.8 18.8 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 EER26113.1 - 6.8 5.4 8.6 7.7 5.2 8.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Hid1 PF12722.7 EER26113.1 - 8.1 4.4 14.5 10 4.1 14.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Motile_Sperm PF00635.26 EER26114.1 - 3.4e-21 75.1 0.1 2.6e-15 56.2 0.1 2.5 2 0 0 2 2 2 2 MSP (Major sperm protein) domain DotU PF09850.9 EER26114.1 - 0.0026 17.5 0.1 0.0042 16.8 0.1 1.3 1 0 0 1 1 1 1 Type VI secretion system protein DotU HR1 PF02185.16 EER26114.1 - 0.019 15.1 1.8 0.047 13.8 1.8 1.7 1 0 0 1 1 1 0 Hr1 repeat Prefoldin_2 PF01920.20 EER26114.1 - 0.045 13.7 1.7 0.094 12.7 1.7 1.5 1 0 0 1 1 1 0 Prefoldin subunit Sec8_exocyst PF04048.14 EER26114.1 - 0.046 13.6 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain FlxA PF14282.6 EER26114.1 - 0.067 13.2 4.3 0.15 12.0 4.3 1.6 1 0 0 1 1 1 0 FlxA-like protein KfrA_N PF11740.8 EER26114.1 - 0.12 13.1 3.6 0.13 13.0 2.3 1.7 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term BBS2_C PF14782.6 EER26114.1 - 0.12 11.1 1.0 0.29 9.9 0.0 1.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal THOC7 PF05615.13 EER26114.1 - 0.16 12.3 2.4 0.39 11.0 2.4 1.6 1 0 0 1 1 1 0 Tho complex subunit 7 EAP30 PF04157.16 EER26114.1 - 0.21 10.8 0.8 0.65 9.2 0.6 1.7 2 0 0 2 2 2 0 EAP30/Vps36 family TPR_MLP1_2 PF07926.12 EER26114.1 - 0.37 10.9 6.4 0.35 11.0 4.1 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FA_desaturase PF00487.24 EER26115.1 - 6.7e-24 85.1 9.8 1.1e-23 84.4 9.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EER26115.1 - 1.3e-17 62.9 0.2 2.2e-17 62.2 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M24 PF00557.24 EER26116.1 - 4.1e-43 147.5 0.0 5.3e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.19 EER26116.1 - 0.021 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase RNA_polI_A34 PF08208.11 EER26116.1 - 0.53 10.4 11.7 0.82 9.7 11.7 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PGA2 PF07543.12 EER26116.1 - 0.76 9.8 9.8 1.7 8.6 9.8 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF3381 PF11861.8 EER26116.1 - 1.7 8.4 10.5 3.1 7.6 10.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) UPF0239 PF06783.11 EER26116.1 - 1.8 8.8 7.7 4.5 7.5 7.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) RNA_pol_Rpc4 PF05132.14 EER26116.1 - 5.4 7.4 7.5 8.7 6.8 7.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 CDC45 PF02724.14 EER26116.1 - 6.6 4.9 8.9 9.2 4.4 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.31 EER26117.1 - 5.5e-21 74.5 1.6 1.3e-20 73.3 1.6 1.7 1 0 0 1 1 1 1 DnaJ domain GREB1 PF15782.5 EER26117.1 - 0.051 10.7 6.4 0.061 10.4 6.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer C1_2 PF03107.16 EER26117.1 - 0.49 10.7 6.5 0.9 9.9 6.5 1.4 1 0 0 1 1 1 0 C1 domain Zn_ribbon_17 PF17120.5 EER26117.1 - 0.76 9.4 5.9 1.6 8.4 5.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Sporozoite_P67 PF05642.11 EER26117.1 - 3.1 5.8 6.2 4.2 5.3 6.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4407 PF14362.6 EER26117.1 - 3.4 6.9 23.7 0.32 10.3 3.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 EER26117.1 - 7.2 6.1 28.4 0.54 9.8 21.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) DnaJ PF00226.31 EER26118.1 - 4.8e-23 81.1 0.6 4.8e-23 81.1 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain Porin_3 PF01459.22 EER26119.1 - 3.7e-76 256.1 3.3 4.2e-76 256.0 3.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin YL1_C PF08265.11 EER26119.1 - 0.12 12.2 1.1 0.33 10.7 0.1 2.2 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Asn_synthase PF00733.21 EER26120.1 - 7.3e-93 312.1 0.1 1.9e-55 189.0 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EER26120.1 - 2e-36 124.6 0.0 1e-35 122.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EER26120.1 - 2.5e-27 95.7 0.0 1.2e-26 93.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EER26120.1 - 2.9e-06 26.9 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EER26120.1 - 0.025 13.7 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD synthase UQ_con PF00179.26 EER26121.1 - 8.1e-49 164.9 0.0 9.1e-49 164.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER26121.1 - 1.6e-06 27.9 0.0 2.3e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EER26121.1 - 0.018 15.3 1.0 0.05 13.9 1.0 1.8 1 1 0 1 1 1 0 RWD domain G-patch PF01585.23 EER26122.1 - 7e-11 41.9 2.0 1.4e-10 40.9 2.0 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EER26122.1 - 0.00011 21.9 0.3 0.00044 20.0 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.7 EER26122.1 - 0.014 15.5 0.3 0.056 13.5 0.3 2.0 1 0 0 1 1 1 0 G-patch domain DUF5559 PF17714.1 EER26122.1 - 0.09 12.7 1.2 0.25 11.2 1.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5559) Limkain-b1 PF11608.8 EER26122.1 - 0.17 12.0 0.5 0.89 9.7 0.1 2.3 3 0 0 3 3 3 0 Limkain b1 AMP-binding PF00501.28 EER26123.1 - 2.1e-85 286.9 0.0 2.8e-85 286.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER26123.1 - 2.2e-12 47.7 0.3 5.3e-12 46.5 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EER26123.1 - 1.9e-05 23.7 0.0 0.00031 19.8 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 EER26123.1 - 0.048 13.7 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 RTX C-terminal domain YCII PF03795.14 EER26124.1 - 1e-06 29.1 0.0 1.6e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Anp1 PF03452.14 EER26125.1 - 8.8e-104 346.6 0.0 1.4e-103 345.9 0.0 1.2 1 0 0 1 1 1 1 Anp1 Ecm33 PF12454.8 EER26126.1 - 4.1e-13 49.2 0.0 1.1e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.24 EER26126.1 - 9e-08 32.2 6.9 0.059 13.5 0.0 4.6 1 1 3 4 4 4 3 Receptor L domain LRR_5 PF13306.6 EER26126.1 - 0.0018 18.3 2.9 0.94 9.4 0.9 2.6 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) AA_permease_2 PF13520.6 EER26127.1 - 2.4e-51 174.9 43.0 3e-51 174.6 43.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER26127.1 - 3e-21 75.6 40.5 4e-21 75.2 40.5 1.1 1 0 0 1 1 1 1 Amino acid permease HhH-GPD PF00730.25 EER26128.1 - 2.3e-14 53.8 0.0 2.7e-13 50.3 0.0 2.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein IGR PF09597.10 EER26128.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 IGR protein motif Cupin_1 PF00190.22 EER26129.1 - 4.9e-33 113.9 0.0 5.3e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EER26129.1 - 4.2e-22 77.7 0.7 1.3e-10 40.9 0.2 2.7 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EER26129.1 - 0.0001 21.9 0.1 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EER26129.1 - 0.01 15.8 0.6 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain 3-HAO PF06052.12 EER26129.1 - 0.021 14.4 0.0 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase UCR_14kD PF02271.16 EER26130.1 - 1.1e-43 147.2 2.2 1.5e-43 146.8 2.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 EER26131.1 - 5e-65 215.5 1.4 5.3e-23 80.8 0.0 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein ABC1 PF03109.16 EER26132.1 - 7.7e-35 119.6 0.0 1.3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EER26132.1 - 0.031 13.9 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EER26133.1 - 1.8e-71 240.6 0.0 5.5e-71 239.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26133.1 - 5.9e-51 173.2 0.0 1.5e-50 171.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER26133.1 - 0.0032 16.3 0.0 0.007 15.2 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase DUF383 PF04063.14 EER26133.1 - 0.083 12.5 0.3 0.21 11.2 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF383) EF-G-binding_N PF07299.11 EER26133.1 - 0.12 13.0 0.7 0.55 10.8 0.0 2.5 3 0 0 3 3 3 0 Elongation factor G-binding protein, N-terminal GerD PF17898.1 EER26133.1 - 0.19 11.7 0.5 0.51 10.3 0.5 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain Exo70 PF03081.15 EER26133.1 - 0.71 8.9 4.6 0.77 8.7 0.3 2.7 3 0 0 3 3 3 0 Exo70 exocyst complex subunit DUF4704 PF15787.5 EER26133.1 - 1.2 8.3 10.9 8.3 5.5 1.3 4.1 4 1 0 4 4 4 0 Domain of unknown function (DUF4704) Mur_ligase_M PF08245.12 EER26134.1 - 1.1e-07 32.0 0.1 1.8e-07 31.4 0.1 1.3 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EER26134.1 - 0.0074 16.5 0.0 0.034 14.4 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain SRC-1 PF08832.10 EER26135.1 - 0.0086 17.1 3.8 0.031 15.3 0.0 2.8 3 0 0 3 3 3 1 Steroid receptor coactivator AAA_18 PF13238.6 EER26136.1 - 0.0002 21.9 0.0 0.025 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain PRK PF00485.18 EER26136.1 - 0.00047 20.0 0.0 0.00084 19.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EER26136.1 - 0.00089 18.6 0.5 0.064 12.5 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin dNK PF01712.19 EER26136.1 - 0.0012 18.8 0.0 0.0033 17.3 0.0 1.8 2 0 0 2 2 2 1 Deoxynucleoside kinase AAA_33 PF13671.6 EER26136.1 - 0.0026 17.9 0.2 1.1 9.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EER26136.1 - 0.0042 17.4 0.0 0.0063 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EER26136.1 - 0.0042 16.3 0.0 0.0066 15.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.6 EER26136.1 - 0.016 15.6 0.1 0.71 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EER26136.1 - 0.018 15.6 0.0 0.034 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Cytidylate_kin PF02224.18 EER26136.1 - 0.028 14.1 0.0 0.059 13.1 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase KAP_NTPase PF07693.14 EER26136.1 - 0.039 13.2 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_16 PF13191.6 EER26136.1 - 0.05 14.0 0.0 0.14 12.5 0.0 1.7 1 1 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 EER26136.1 - 0.053 13.3 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 EER26136.1 - 0.061 13.8 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 EER26136.1 - 0.1 12.3 0.0 16 5.1 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase MMR_HSR1 PF01926.23 EER26136.1 - 0.12 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 EER26136.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Ribonuc_red_lgC PF02867.15 EER26138.1 - 1.2e-185 618.1 0.0 1.6e-185 617.6 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EER26138.1 - 6.9e-25 86.9 0.0 1.5e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EER26138.1 - 4.7e-16 59.1 0.1 1.1e-15 58.0 0.1 1.6 1 0 0 1 1 1 1 ATP cone domain DPBB_1 PF03330.18 EER26139.1 - 0.0046 17.2 0.1 0.011 15.9 0.1 1.7 1 1 0 1 1 1 1 Lytic transglycolase DNA_ligase_OB_2 PF14743.6 EER26139.1 - 0.035 14.1 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA ligase OB-like domain ELFV_dehydrog PF00208.21 EER26140.1 - 3.1e-80 269.4 0.6 3.8e-80 269.1 0.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EER26140.1 - 3.3e-50 169.3 0.0 5.8e-50 168.5 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 EER26140.1 - 0.19 12.2 0.1 0.59 10.6 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding HATPase_c_3 PF13589.6 EER26141.1 - 3.9e-19 68.8 0.0 6.5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EER26141.1 - 2.7e-11 43.4 0.0 3e-10 40.0 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EER26141.1 - 0.0027 18.2 0.0 0.0055 17.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Xan_ur_permease PF00860.20 EER26142.1 - 0.088 11.5 0.5 0.12 11.0 0.5 1.1 1 0 0 1 1 1 0 Permease family adh_short PF00106.25 EER26143.1 - 2e-36 125.3 0.0 2.8e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER26143.1 - 1.9e-26 93.1 0.0 2.6e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER26143.1 - 0.00049 20.0 0.0 0.063 13.2 0.0 2.2 2 0 0 2 2 2 2 KR domain GHMP_kinases_N PF00288.26 EER26144.1 - 2.3e-11 43.8 0.1 4.4e-11 42.9 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EER26144.1 - 0.00031 21.1 0.0 0.00065 20.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Med5 PF08689.10 EER26145.1 - 6.6e-156 520.9 0.0 4.9e-155 518.1 0.0 2.1 1 1 0 1 1 1 1 Mediator complex subunit Med5 DUF3984 PF13136.6 EER26147.1 - 1.8e-100 336.6 22.6 1.8e-100 336.6 22.6 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) Peptidase_S51 PF03575.17 EER26147.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 OTCace PF00185.24 EER26148.1 - 2.2e-45 154.5 0.0 3.3e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EER26148.1 - 4.5e-45 153.3 0.0 7.4e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DRTGG PF07085.12 EER26148.1 - 0.026 14.3 0.1 0.79 9.5 0.0 2.3 2 0 0 2 2 2 0 DRTGG domain DUF3712 PF12505.8 EER26149.1 - 2.6e-09 37.4 1.1 6.4e-08 32.9 0.4 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EER26149.1 - 0.0093 16.5 0.9 3.7 8.1 0.0 3.4 3 1 0 3 3 3 2 Late embryogenesis abundant protein ALS_ss_C PF10369.9 EER26150.1 - 4.2e-14 52.5 0.0 7e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EER26150.1 - 2.3e-12 46.4 0.2 3.9e-12 45.7 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EER26150.1 - 4.7e-08 32.8 0.0 9.7e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EER26150.1 - 0.039 13.9 0.0 14 5.7 0.0 2.6 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.29 EER26151.1 - 3.3e-10 39.6 0.1 3.9e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 KH domain ATLF PF07737.11 EER26151.1 - 0.091 12.0 0.0 0.2 10.9 0.0 1.5 2 0 0 2 2 2 0 Anthrax toxin lethal factor, N- and C-terminal domain Meiotic_rec114 PF03525.14 EER26151.1 - 0.1 11.6 2.4 0.17 10.8 2.4 1.2 1 0 0 1 1 1 0 Meiotic recombination protein rec114 DEAD PF00270.29 EER26152.1 - 1.4e-16 60.7 0.0 4.5e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26152.1 - 9e-14 51.8 0.0 5.9e-10 39.5 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EER26152.1 - 6.4e-05 23.6 2.0 0.00019 22.1 2.0 1.8 1 0 0 1 1 1 1 RecQ zinc-binding PPR_2 PF13041.6 EER26153.1 - 3.3e-07 30.4 0.3 0.13 12.5 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 EER26153.1 - 3.3e-06 27.0 5.5 0.26 11.6 0.0 6.1 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 EER26153.1 - 0.0065 15.8 0.0 0.014 14.8 0.0 1.6 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EER26153.1 - 0.2 11.7 0.0 2.1 8.5 0.0 2.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain MRP-S25 PF13741.6 EER26154.1 - 2.1e-86 289.2 4.7 2.5e-86 289.0 4.7 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EER26154.1 - 8.2e-06 26.1 0.4 0.066 13.5 0.0 2.7 3 0 0 3 3 3 2 Mitochondrial ribosomal protein S23 hGDE_N PF14699.6 EER26154.1 - 0.076 13.2 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme SOG2 PF10428.9 EER26155.1 - 8e-100 335.4 2.4 8e-100 335.4 2.4 4.2 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 EER26155.1 - 3.2e-14 52.4 15.6 2.5e-08 33.6 1.9 3.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EER26155.1 - 3.6e-11 43.1 5.8 1.4e-05 25.3 0.9 3.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EER26155.1 - 0.036 14.6 4.7 71 4.6 0.0 5.8 5 0 0 5 5 5 0 Leucine Rich Repeat Plk4_PB2 PF18409.1 EER26155.1 - 0.037 14.7 2.9 13 6.6 0.0 3.5 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 LRR_6 PF13516.6 EER26155.1 - 0.11 12.7 6.7 8.7 6.7 0.1 4.7 4 0 0 4 4 4 0 Leucine Rich repeat ATPase PF06745.13 EER26155.1 - 0.15 11.4 0.3 0.32 10.3 0.3 1.5 1 0 0 1 1 1 0 KaiC Peptidase_S10 PF00450.22 EER26156.1 - 4.9e-84 283.2 0.0 8e-84 282.5 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase DUF4454 PF14628.6 EER26156.1 - 0.037 13.9 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) Tcp11 PF05794.13 EER26157.1 - 1.7e-101 340.5 0.1 2e-101 340.3 0.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 Ydc2-catalyt PF09159.10 EER26158.1 - 1.1e-93 314.1 0.2 1.4e-93 313.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EER26158.1 - 0.013 15.6 0.0 10 6.2 0.0 3.4 3 0 0 3 3 3 0 Poxvirus A22 protein SAP PF02037.27 EER26158.1 - 0.034 13.9 2.1 0.08 12.7 0.1 2.5 2 0 0 2 2 2 0 SAP domain PT PF04886.12 EER26159.1 - 6.6 6.4 27.2 1.8e+04 -8.9 27.2 4.1 1 1 0 1 1 1 0 PT repeat CTP_transf_like PF01467.26 EER26160.1 - 0.0043 17.3 0.1 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase-like Aim19 PF10315.9 EER26161.1 - 1.7e-05 25.1 0.2 3.6e-05 24.0 0.2 1.6 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF1977 PF09320.11 EER26162.1 - 2.5e-33 114.5 0.2 5.2e-33 113.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EER26162.1 - 1.7e-22 79.3 0.6 2.8e-22 78.6 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain Ufd2P_core PF10408.9 EER26163.1 - 1.1e-216 721.3 13.1 1.3e-216 721.1 13.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EER26163.1 - 4.5e-24 84.4 1.6 7.9e-24 83.6 0.3 2.2 2 0 0 2 2 2 1 U-box domain Homez PF11569.8 EER26163.1 - 0.055 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Cep57_MT_bd PF06657.13 EER26163.1 - 1.4 9.4 4.8 0.45 11.0 0.6 2.2 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Steroid_dh PF02544.16 EER26164.1 - 6.7e-09 35.9 11.6 6.2e-06 26.3 2.5 3.9 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase Meth_synt_2 PF01717.18 EER26165.1 - 1.6e-152 507.4 0.0 1.7e-149 497.5 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EER26165.1 - 6.6e-118 393.8 0.0 3.4e-111 371.7 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EER26165.1 - 0.0023 17.1 0.1 0.071 12.2 0.0 2.9 3 1 0 3 3 3 1 Uroporphyrinogen decarboxylase (URO-D) SANT_DAMP1_like PF16282.5 EER26167.1 - 1.9e-31 108.1 1.0 3.7e-31 107.1 1.0 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EER26167.1 - 0.0017 18.2 6.4 0.0017 18.2 6.4 2.9 2 1 1 3 3 3 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 EER26167.1 - 0.061 13.6 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain ATP-synt_E PF05680.12 EER26167.1 - 0.19 12.1 9.3 1.9 8.9 4.5 3.3 3 0 0 3 3 3 0 ATP synthase E chain ASFV_J13L PF05568.11 EER26167.1 - 0.23 11.2 5.9 0.48 10.2 5.9 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein EMP24_GP25L PF01105.24 EER26168.1 - 6e-51 173.0 0.0 7.4e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD adh_short_C2 PF13561.6 EER26169.1 - 1.7e-45 155.4 0.2 2e-45 155.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER26169.1 - 1.4e-44 151.9 0.0 1.8e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER26169.1 - 2.4e-13 50.4 0.4 3.7e-13 49.8 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EER26169.1 - 5.7e-05 22.7 0.3 0.00085 18.8 0.2 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Prenyltransf PF01255.19 EER26169.1 - 0.006 16.1 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase GDP_Man_Dehyd PF16363.5 EER26169.1 - 0.016 14.6 0.1 0.26 10.6 0.0 2.2 1 1 1 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EER26169.1 - 0.04 13.1 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1712 PF08217.11 EER26170.1 - 1.7e-17 63.2 0.0 6.3e-15 54.7 0.0 2.4 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Cache_3-Cache_2 PF17201.4 EER26171.1 - 0.22 10.8 0.1 0.32 10.2 0.1 1.2 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain PNK3P PF08645.11 EER26172.1 - 7.2e-50 168.8 0.0 1.3e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EER26172.1 - 1.6e-27 96.4 0.0 1.8e-24 86.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 EER26172.1 - 6.2e-05 22.6 0.0 0.058 12.8 0.0 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EER26172.1 - 0.18 11.1 0.0 0.95 8.7 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EER26172.1 - 0.18 11.7 0.0 0.56 10.1 0.0 1.7 2 0 0 2 2 2 0 NTPase Med18 PF09637.10 EER26173.1 - 4.2e-68 229.9 0.0 4.8e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Med18 protein S36_mt PF10937.8 EER26174.1 - 5.6e-41 140.8 0.2 6.4e-41 140.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial DUF647 PF04884.14 EER26175.1 - 1.5e-92 309.6 5.8 2.1e-92 309.1 5.8 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis HTH_39 PF14090.6 EER26175.1 - 0.054 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain RGS PF00615.19 EER26176.1 - 5.9e-12 45.9 0.0 8.1e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.25 EER26177.1 - 2.2e-27 96.1 0.0 2.7e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26177.1 - 1.4e-14 54.0 0.0 1.8e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER26177.1 - 8.9e-07 28.0 0.1 1.2e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Rtt106 PF08512.12 EER26178.1 - 1.2e-28 99.3 0.1 3e-28 98.1 0.1 1.7 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EER26178.1 - 0.18 11.8 0.0 0.71 9.8 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain KOW PF00467.29 EER26179.1 - 1.8e-05 24.5 0.2 1.8e-05 24.5 0.2 1.9 2 0 0 2 2 2 1 KOW motif Ras PF00071.22 EER26180.1 - 1.2e-54 184.3 0.0 1.4e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER26180.1 - 3.6e-22 78.8 0.0 5e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER26180.1 - 2e-07 30.6 0.0 3.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EER26180.1 - 0.00098 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EER26180.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Alg14 PF08660.11 EER26181.1 - 4.7e-52 176.5 0.0 9.5e-37 126.6 0.0 2.2 1 1 1 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like REV PF00424.18 EER26181.1 - 0.12 12.4 0.1 0.47 10.5 0.1 2.0 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Ima1_N PF09779.9 EER26182.1 - 3e-37 128.5 10.8 4.8e-37 127.8 10.8 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.7 EER26182.1 - 0.0019 18.2 4.4 0.0019 18.2 4.4 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 EER26182.1 - 0.053 13.4 1.3 0.15 12.0 1.3 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Apt1 PF10351.9 EER26183.1 - 0.068 12.0 4.4 0.078 11.8 4.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Rrn6 PF10214.9 EER26183.1 - 0.3 9.5 16.0 0.39 9.1 16.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Macoilin PF09726.9 EER26183.1 - 1 7.9 4.0 1.2 7.7 4.0 1.1 1 0 0 1 1 1 0 Macoilin family PAP1 PF08601.10 EER26183.1 - 1.4 8.6 17.2 2.1 8.0 17.2 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DUF4718 PF15842.5 EER26183.1 - 6.4 6.5 11.3 11 5.8 11.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Chorismate_synt PF01264.21 EER26184.1 - 9.7e-140 464.9 0.0 1.1e-139 464.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.19 EER26185.1 - 0.0019 18.1 0.0 0.0051 16.7 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Kelch_4 PF13418.6 EER26186.1 - 0.015 15.3 0.2 6.4 6.9 0.0 4.4 4 0 0 4 4 4 0 Galactose oxidase, central domain Kelch_5 PF13854.6 EER26186.1 - 0.025 14.6 0.0 4.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Pkinase PF00069.25 EER26187.1 - 1.7e-52 178.4 0.1 2.1e-34 119.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER26187.1 - 1.1e-26 93.7 0.0 1.1e-25 90.4 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER26187.1 - 3.8e-05 22.7 0.9 0.00016 20.6 0.9 2.1 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EER26187.1 - 0.0025 17.8 0.0 0.014 15.3 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EER26187.1 - 0.0036 16.7 0.0 0.008 15.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like zf-H2C2_2 PF13465.6 EER26188.1 - 5.6e-12 45.5 8.9 2.1e-07 31.1 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EER26188.1 - 3.3e-11 43.0 17.7 2.6e-06 27.5 2.3 4.0 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER26188.1 - 2.2e-08 34.2 10.2 0.00084 20.0 1.4 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EER26188.1 - 5.6e-08 32.6 5.2 0.00053 19.9 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER26188.1 - 1.9e-05 24.8 0.6 0.38 11.1 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER26188.1 - 4.8e-05 23.6 1.0 0.014 15.8 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EER26188.1 - 0.016 15.0 4.2 1.2 8.9 0.5 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 EER26188.1 - 0.08 13.5 1.1 0.19 12.3 1.1 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 EER26188.1 - 0.11 12.8 1.4 0.21 11.9 1.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EER26188.1 - 0.18 12.3 1.8 7.5 7.1 0.3 2.7 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FYVE PF01363.21 EER26188.1 - 0.98 9.6 4.1 2.1 8.6 4.1 1.6 1 1 0 1 1 1 0 FYVE zinc finger LIM PF00412.22 EER26188.1 - 1.5 9.1 5.1 25 5.2 3.0 2.8 2 1 1 3 3 3 0 LIM domain C5HCH PF17982.1 EER26188.1 - 2.6 8.3 5.9 11 6.3 1.0 2.7 1 1 1 2 2 2 0 NSD Cys-His rich domain ALG11_N PF15924.5 EER26189.1 - 9.3e-83 277.4 0.0 1.3e-82 276.9 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EER26189.1 - 1.3e-17 63.8 0.0 2.3e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EER26189.1 - 1.1e-05 25.9 0.0 4.9e-05 23.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EER26189.1 - 0.063 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 60KD_IMP PF02096.20 EER26190.1 - 5.8e-13 49.1 2.0 3e-12 46.8 0.2 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein GIIM PF08388.11 EER26190.1 - 0.0025 17.8 1.1 0.0075 16.3 0.2 2.3 2 1 0 2 2 2 1 Group II intron, maturase-specific domain ExoD PF06055.12 EER26190.1 - 0.045 13.1 0.6 0.045 13.1 0.6 1.6 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD PP2C PF00481.21 EER26191.1 - 1.8e-45 155.6 0.0 4e-45 154.5 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EER26191.1 - 1.8e-05 24.5 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EER26191.1 - 0.001 19.0 0.0 0.14 12.1 0.0 2.7 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Tap-RNA_bind PF09162.10 EER26191.1 - 0.16 11.8 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Tap, RNA-binding Tcf25 PF04910.14 EER26192.1 - 2.3e-76 257.1 0.0 3.3e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PGA2 PF07543.12 EER26192.1 - 6.4 6.7 9.3 13 5.8 9.3 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 PQ-loop PF04193.14 EER26193.1 - 1.1e-40 137.2 6.4 7.5e-21 73.7 0.2 2.8 2 0 0 2 2 2 2 PQ loop repeat Ribosomal_60s PF00428.19 EER26194.1 - 2.5e-26 92.1 11.2 3e-26 91.8 11.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.8 EER26194.1 - 0.35 9.4 2.3 0.39 9.3 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF2408 PF10303.9 EER26195.1 - 1.8e-46 158.0 5.0 6.2e-28 98.0 0.0 5.5 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) ApoLp-III PF07464.11 EER26195.1 - 0.0083 16.2 0.1 2.5 8.2 0.0 2.6 2 1 1 3 3 3 2 Apolipophorin-III precursor (apoLp-III) Snapin_Pallidin PF14712.6 EER26195.1 - 0.36 11.3 7.1 2.8 8.4 0.0 4.5 6 0 0 6 6 6 0 Snapin/Pallidin Aconitase PF00330.20 EER26196.1 - 3.7e-145 484.4 0.0 4.6e-145 484.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EER26196.1 - 2e-40 138.2 0.0 3.1e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain NmrA PF05368.13 EER26197.1 - 4.8e-25 88.5 0.0 5.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EER26197.1 - 5.7e-09 36.1 0.0 1.7e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EER26197.1 - 2.8e-05 23.3 0.0 4.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EER26197.1 - 0.00054 19.5 0.0 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EER26197.1 - 0.0006 20.2 0.0 0.0015 18.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Importin_rep_4 PF18808.1 EER26198.1 - 2.1e-33 114.5 0.7 3.5e-32 110.6 0.8 2.9 2 0 0 2 2 2 1 Importin repeat HEAT_EZ PF13513.6 EER26198.1 - 3.8e-24 84.8 1.9 2.9e-07 30.8 0.1 8.5 6 1 2 8 8 8 3 HEAT-like repeat Importin_rep_5 PF18816.1 EER26198.1 - 5.8e-22 77.7 2.3 1.2e-21 76.8 1.0 2.4 2 0 0 2 2 1 1 Importin repeat HEAT_2 PF13646.6 EER26198.1 - 7.1e-15 55.2 3.2 0.0034 17.7 0.0 8.2 5 2 3 8 8 8 3 HEAT repeats HEAT PF02985.22 EER26198.1 - 9.1e-14 50.4 4.3 0.71 10.3 0.0 10.6 12 0 0 12 12 11 2 HEAT repeat Importin_rep_6 PF18829.1 EER26198.1 - 3e-13 49.8 2.4 2.6e-12 46.8 0.3 3.3 3 0 0 3 3 3 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EER26198.1 - 4.4e-08 33.6 0.1 0.054 14.1 0.0 6.6 3 2 5 8 8 8 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EER26198.1 - 2.7e-07 30.6 0.0 0.13 12.1 0.0 6.8 3 3 6 9 9 9 3 Domain of unknown function (DUF3385) RIX1 PF08167.12 EER26198.1 - 4.1e-06 26.7 1.3 0.0045 16.7 0.0 4.4 3 3 2 6 6 6 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EER26198.1 - 7.1e-06 25.7 0.2 0.0019 17.8 0.1 4.2 3 1 1 4 4 4 1 CLASP N terminal Ecm29 PF13001.7 EER26198.1 - 9.4e-06 24.6 1.5 0.7 8.5 0.1 4.1 3 1 2 5 5 5 2 Proteasome stabiliser MMS19_C PF12460.8 EER26198.1 - 1.7e-05 24.2 5.9 7.5e-05 22.0 0.0 4.3 4 2 1 5 5 5 1 RNAPII transcription regulator C-terminal IBN_N PF03810.19 EER26198.1 - 8.5e-05 22.4 0.2 0.0042 17.0 0.1 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain TFCD_C PF12612.8 EER26198.1 - 0.00018 21.4 0.1 7.8 6.3 0.0 3.9 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal Arm PF00514.23 EER26198.1 - 0.0007 19.5 2.7 2 8.6 0.1 4.0 4 0 0 4 4 3 2 Armadillo/beta-catenin-like repeat Rif1_N PF12231.8 EER26198.1 - 0.0027 16.8 0.1 0.57 9.1 0.0 2.7 2 1 0 2 2 2 1 Rap1-interacting factor 1 N terminal BP28CT PF08146.12 EER26198.1 - 0.0086 15.9 1.6 1.1 9.1 0.0 3.8 3 1 1 4 4 4 1 BP28CT (NUC211) domain RTP1_C1 PF10363.9 EER26198.1 - 0.022 14.9 0.0 1.8 8.8 0.1 4.0 4 0 0 4 4 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TAN PF11640.8 EER26198.1 - 0.035 14.2 0.5 0.64 10.1 0.1 3.4 4 1 1 5 5 4 0 Telomere-length maintenance and DNA damage repair V-ATPase_H_N PF03224.14 EER26198.1 - 0.29 10.4 3.8 0.91 8.8 0.1 3.3 3 1 0 3 3 3 0 V-ATPase subunit H CBS PF00571.28 EER26199.1 - 6.7e-37 125.7 4.8 4.6e-09 36.6 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EER26199.1 - 1.7e-10 40.7 0.0 7.9e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 PB1 domain Ribosomal_S26e PF01283.19 EER26200.1 - 2.9e-52 175.7 8.0 3.6e-52 175.4 8.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EER26200.1 - 0.02 14.8 1.1 0.033 14.2 0.1 1.8 2 0 0 2 2 2 0 Zinc binding domain DUF4668 PF15701.5 EER26200.1 - 0.21 11.4 1.9 0.27 11.0 1.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4668) F-box-like PF12937.7 EER26201.1 - 2.1e-05 24.3 1.7 3.2e-05 23.7 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EER26201.1 - 0.093 12.6 0.1 0.093 12.6 0.1 2.6 3 0 0 3 3 3 0 F-box domain LRR_6 PF13516.6 EER26201.1 - 2.2 8.6 10.9 12 6.2 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Peptidase_C14 PF00656.22 EER26202.1 - 2.2e-62 211.3 0.0 2.7e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Cpn60_TCP1 PF00118.24 EER26203.1 - 8.4e-153 509.5 6.0 9.6e-153 509.3 6.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 EER26203.1 - 0.039 14.4 0.0 4.8 7.7 0.0 2.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain Beta_helix_2 PF18835.1 EER26203.1 - 0.05 13.4 0.0 5 7.0 0.0 2.7 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase zf-H2C2 PF09337.10 EER26204.1 - 4.5e-14 52.4 2.0 8.2e-14 51.5 2.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EER26204.1 - 3e-11 43.2 0.6 7.2e-11 42.0 0.6 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EER26204.1 - 0.00094 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EER26204.1 - 0.0079 16.9 0.0 0.022 15.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EER26204.1 - 0.014 15.5 0.0 0.14 12.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ribo_biogen_C PF04034.13 EER26205.1 - 1.8e-51 173.2 0.0 2.7e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EER26205.1 - 1.4e-10 40.8 0.5 1.4e-10 40.8 0.5 1.7 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI VHS PF00790.19 EER26206.1 - 4.5e-46 156.2 0.0 1.5e-45 154.5 0.0 1.9 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 EER26206.1 - 9.9e-22 77.4 0.6 9.9e-22 77.4 0.6 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 EER26206.1 - 1.3e-20 73.5 0.7 1.3e-20 73.5 0.7 2.6 4 0 0 4 4 4 1 GAT domain GGA_N-GAT PF18308.1 EER26206.1 - 7.6e-07 28.6 0.5 3.8e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 GGA N-GAT domain PIN_8 PF18476.1 EER26206.1 - 0.098 12.5 1.7 0.33 10.8 2.0 1.7 2 0 0 2 2 2 0 PIN like domain TAP42 PF04177.12 EER26207.1 - 0.11 11.6 4.9 0.18 10.9 4.9 1.2 1 0 0 1 1 1 0 TAP42-like family CBS PF00571.28 EER26208.1 - 7.7e-17 61.5 1.2 0.00051 20.4 0.1 5.3 5 0 0 5 5 5 4 CBS domain Baculo_PEP_C PF04513.12 EER26210.1 - 0.16 12.0 2.9 0.31 11.1 2.9 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.8 EER26210.1 - 0.41 10.7 8.8 1.5 8.9 3.1 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 EER26210.1 - 0.44 10.6 13.6 2.8 8.0 8.6 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 EER26210.1 - 1.5 8.3 10.9 1.7 8.2 10.1 1.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2183 PF09949.9 EER26211.1 - 1.4e-33 115.1 0.1 2.9e-33 114.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EER26211.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) ADH_zinc_N_2 PF13602.6 EER26212.1 - 3.2e-16 60.6 0.0 4.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER26212.1 - 0.00074 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Importin_rep_3 PF18806.1 EER26212.1 - 0.021 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat GPP34 PF05719.11 EER26213.1 - 5.7e-66 222.4 0.1 7.4e-66 222.1 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.25 EER26214.1 - 2.3e-11 43.9 0.2 3.4e-11 43.3 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EER26214.1 - 3.5e-06 27.2 0.2 5.8e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.27 EER26215.1 - 1.7e-13 49.7 16.5 6.2e-08 32.1 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EER26215.1 - 5.8e-13 49.2 10.1 9.4e-13 48.5 10.1 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EER26215.1 - 6.2e-10 39.9 8.0 7.7e-05 23.6 0.6 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EER26215.1 - 1.4e-09 37.9 4.9 0.0002 21.4 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EER26215.1 - 9.1e-09 35.3 20.8 2e-06 27.8 12.1 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EER26215.1 - 1.3e-08 34.9 8.8 2.3e-08 34.1 8.8 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EER26215.1 - 1.8e-08 34.7 3.2 0.00032 21.1 0.2 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EER26215.1 - 1.6e-06 27.9 17.1 0.0004 20.3 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EER26215.1 - 5e-06 26.3 11.8 0.01 15.9 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EER26215.1 - 1.1e-05 25.5 11.7 0.00035 20.8 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EER26215.1 - 0.00032 21.2 11.5 0.071 13.7 12.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EER26215.1 - 0.012 15.8 5.4 0.37 11.0 0.2 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 EER26215.1 - 0.065 13.8 15.0 0.76 10.4 4.3 2.7 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EER26215.1 - 0.077 13.2 8.9 1.2 9.3 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EER26215.1 - 0.089 12.9 5.6 0.47 10.6 0.6 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 EER26215.1 - 0.25 12.3 15.5 0.43 11.6 3.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 EER26215.1 - 0.71 10.8 11.8 3.4 8.6 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain SURF6 PF04935.12 EER26216.1 - 1.9e-51 174.7 38.6 1.9e-51 174.7 38.6 4.0 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 EER26216.1 - 3.7e-18 65.9 0.8 3.7e-18 65.9 0.8 8.1 7 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 Peptidase_S8 PF00082.22 EER26218.1 - 5.4e-30 104.7 8.9 2.3e-29 102.6 8.2 2.0 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 EER26218.1 - 1.2e-17 64.3 0.1 2.5e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 TBPIP_N PF15517.6 EER26218.1 - 0.11 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 TBP-interacting protein N-terminus Rick_17kDa_Anti PF05433.15 EER26219.1 - 1.7e-05 24.6 11.3 1.7e-05 24.6 11.3 2.7 3 0 0 3 3 3 1 Glycine zipper 2TM domain Ribosomal_S2 PF00318.20 EER26220.1 - 2.2e-66 223.2 0.1 1.9e-65 220.1 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S2 Mito_carr PF00153.27 EER26221.1 - 8.9e-57 189.0 1.5 5.4e-18 64.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.27 EER26222.1 - 1.1e-32 113.2 5.2 3.3e-31 108.3 5.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EER26222.1 - 1.9e-27 95.5 1.6 4.7e-27 94.2 1.6 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EER26222.1 - 1.3e-10 41.4 1.3 2.7e-10 40.3 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase IF2_N PF04760.15 EER26222.1 - 1.2e-09 37.8 0.0 5.7e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.25 EER26222.1 - 2e-05 24.9 1.5 0.065 13.6 0.2 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Arf PF00025.21 EER26222.1 - 0.00012 21.6 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EER26222.1 - 0.00017 21.6 3.6 0.0091 15.9 0.6 2.4 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EER26222.1 - 0.0019 17.7 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EER26222.1 - 0.0087 15.6 0.6 0.026 14.1 0.6 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 EER26222.1 - 0.023 14.3 0.1 0.045 13.4 0.1 1.4 1 0 0 1 1 1 0 Ras family GTP_EFTU_D4 PF14578.6 EER26222.1 - 0.026 14.4 1.0 0.061 13.2 0.3 2.1 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.23 EER26222.1 - 0.028 14.5 3.1 3.8 7.5 0.2 3.7 3 1 1 4 4 4 0 Dynamin family Roc PF08477.13 EER26222.1 - 0.033 14.4 0.0 0.081 13.1 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Ceramidase_alk PF04734.13 EER26224.1 - 1.5e-212 706.8 0.0 1.7e-212 706.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EER26224.1 - 7.1e-55 185.4 0.0 1.2e-54 184.7 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal BCAS2 PF05700.11 EER26225.1 - 9.3e-69 231.2 2.2 1e-68 231.1 2.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Kelch_5 PF13854.6 EER26226.1 - 3.4e-20 71.6 2.7 1.8e-08 34.2 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EER26226.1 - 1e-11 44.7 9.0 0.059 13.4 0.1 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EER26226.1 - 1.2e-10 41.3 9.3 0.0056 16.9 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EER26226.1 - 8.8e-10 38.6 9.5 0.059 13.7 0.2 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EER26226.1 - 1.1e-07 31.5 4.8 0.0064 16.4 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EER26226.1 - 2.9e-06 26.8 8.3 0.052 13.1 0.2 5.3 5 0 0 5 5 5 3 Kelch motif SKG6 PF08693.10 EER26226.1 - 0.02 14.3 0.2 0.048 13.1 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Snf7 PF03357.21 EER26227.1 - 1.8e-36 125.3 13.4 1.8e-36 125.3 13.4 2.0 1 1 1 2 2 2 1 Snf7 CCDC24 PF15669.5 EER26227.1 - 0.00033 20.6 3.9 0.00033 20.6 3.9 1.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 24 family DUF3138 PF11336.8 EER26227.1 - 0.19 10.3 2.9 0.24 10.0 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Forkhead PF00250.18 EER26228.1 - 1.8e-18 66.5 0.0 4e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EER26228.1 - 2.7e-05 24.4 0.0 5.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Sugar_tr PF00083.24 EER26229.1 - 4.1e-55 187.4 18.4 5.3e-32 111.3 10.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EER26229.1 - 1.1e-11 44.2 28.7 2.8e-07 29.8 15.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily Kinocilin PF15033.6 EER26229.1 - 9.1 5.9 8.1 0.16 11.6 0.2 2.0 2 0 0 2 2 2 0 Kinocilin protein 2OG-FeII_Oxy_3 PF13640.6 EER26231.1 - 1.7e-08 35.2 0.0 3.6e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cNMP_binding PF00027.29 EER26232.1 - 7.1e-44 147.8 0.0 1.8e-22 79.2 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Sugar_tr PF00083.24 EER26233.1 - 9.6e-32 110.4 28.5 2.4e-24 86.0 13.1 2.9 1 1 2 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.16 EER26233.1 - 1.4e-27 96.6 41.0 1.5e-27 96.5 34.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily WW PF00397.26 EER26234.1 - 3.4e-13 49.4 19.9 3e-11 43.2 6.7 3.2 3 0 0 3 3 3 2 WW domain Gly-zipper_Omp PF13488.6 EER26234.1 - 0.66 10.0 14.3 54 3.9 14.3 2.3 1 1 0 1 1 1 0 Glycine zipper PAP2_3 PF14378.6 EER26235.1 - 1.8e-25 89.8 13.1 1.8e-25 89.8 13.1 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EER26235.1 - 1.6e-11 44.1 4.6 1.6e-11 44.1 4.6 2.2 2 0 0 2 2 2 1 PAP2 superfamily LCAT PF02450.15 EER26236.1 - 4.9e-108 361.8 0.0 5.9e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EER26236.1 - 0.018 15.6 0.0 0.089 13.4 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EER26236.1 - 0.13 11.8 0.1 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Yippee-Mis18 PF03226.14 EER26237.1 - 1.5e-18 66.9 0.7 1.7e-18 66.7 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EER26237.1 - 0.0043 17.3 1.2 0.0068 16.6 1.2 1.3 1 1 0 1 1 1 1 C-terminal domain of RIG-I DUF4451 PF14616.6 EER26237.1 - 0.0059 16.8 0.4 0.0079 16.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DUF2039 PF10217.9 EER26237.1 - 0.017 15.5 6.3 0.018 15.4 0.9 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2039) zinc_ribbon_10 PF10058.9 EER26237.1 - 0.017 14.8 0.6 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Endonuclease_7 PF02945.15 EER26237.1 - 0.095 12.6 1.2 0.25 11.3 1.2 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII Pap_E4 PF02711.14 EER26238.1 - 0.016 16.2 0.1 0.016 16.2 0.1 2.3 3 0 0 3 3 3 0 E4 protein RabGAP-TBC PF00566.18 EER26239.1 - 3.1e-31 108.7 1.3 3.1e-31 108.7 1.3 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 EER26240.1 - 3.5e-54 183.9 0.0 6e-54 183.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26240.1 - 3.6e-19 69.1 0.0 5.8e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER26240.1 - 3.3e-05 23.4 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EER26240.1 - 0.00082 18.4 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain PAS_9 PF13426.7 EER26240.1 - 0.001 19.3 0.0 2.2 8.6 0.0 3.4 2 1 0 2 2 2 2 PAS domain Pkinase_fungal PF17667.1 EER26240.1 - 0.0025 16.7 0.0 0.0049 15.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EER26240.1 - 0.0052 16.4 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EER26240.1 - 0.016 15.1 0.1 0.057 13.3 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF3659 PF12396.8 EER26240.1 - 0.14 12.1 0.3 0.28 11.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) LRR_6 PF13516.6 EER26241.1 - 9.8e-12 43.9 18.1 0.039 14.0 0.0 8.8 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 EER26241.1 - 1.5e-11 44.0 0.6 3.9e-11 42.7 0.6 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EER26241.1 - 6e-10 39.2 10.7 0.00066 20.0 0.5 6.2 4 2 3 7 7 7 2 Leucine Rich repeats (2 copies) F-box PF00646.33 EER26241.1 - 3.9e-08 33.0 0.1 1.4e-07 31.2 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 EER26241.1 - 2.4e-06 27.3 20.5 0.85 10.4 0.0 8.6 9 0 0 9 9 9 3 Leucine Rich Repeat PRANC PF09372.10 EER26241.1 - 0.0032 17.7 0.2 0.0076 16.6 0.2 1.6 1 0 0 1 1 1 1 PRANC domain Recep_L_domain PF01030.24 EER26241.1 - 0.022 14.9 0.4 3.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Receptor L domain LRR_8 PF13855.6 EER26241.1 - 1.3 8.8 9.5 17 5.2 0.4 5.0 3 1 1 5 5 5 0 Leucine rich repeat Efg1 PF10153.9 EER26242.1 - 1.3e-29 102.9 11.3 1.3e-29 102.9 11.3 2.7 2 1 0 2 2 2 1 rRNA-processing protein Efg1 Lipase_chap PF03280.14 EER26242.1 - 0.013 15.5 3.0 0.025 14.5 3.0 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Pox_A_type_inc PF04508.12 EER26242.1 - 0.044 13.6 7.8 0.17 11.8 0.7 3.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CCDC-167 PF15188.6 EER26242.1 - 0.061 13.7 8.2 0.17 12.3 7.7 2.1 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 zinc_ribbon_16 PF17034.5 EER26243.1 - 6.6e-22 78.0 8.9 1.3e-21 77.1 8.9 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EER26243.1 - 6.7e-05 22.4 8.3 6.7e-05 22.4 8.3 2.1 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EER26243.1 - 0.008 17.0 3.7 26 5.9 0.0 4.6 4 1 0 4 4 4 0 WD domain, G-beta repeat zf-rbx1 PF12678.7 EER26243.1 - 0.033 14.5 2.4 0.1 12.9 2.4 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain ANAPC4_WD40 PF12894.7 EER26243.1 - 0.047 14.0 0.0 0.84 10.0 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2934 PF11154.8 EER26243.1 - 0.19 11.4 2.1 0.27 11.0 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2934) zf-C3HC4_2 PF13923.6 EER26243.1 - 3.3 7.6 7.5 0.17 11.8 0.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PTS_2-RNA PF01885.16 EER26244.1 - 1.6e-65 220.6 0.0 1.9e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Stb3 PF10330.9 EER26246.1 - 1.9e-37 127.2 0.0 5.5e-37 125.7 0.0 1.8 2 0 0 2 2 2 1 Putative Sin3 binding protein Mito_carr PF00153.27 EER26248.1 - 5.3e-66 218.6 6.1 3.3e-24 84.6 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1_C PF12936.7 EER26249.1 - 2.5e-31 107.7 0.1 2.5e-31 107.7 0.1 4.4 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 EER26249.1 - 3e-28 98.4 23.3 3e-28 98.4 23.3 5.2 4 2 2 6 6 6 1 KRI1-like family VASt PF16016.5 EER26250.1 - 2.2e-34 119.1 0.8 4.7e-34 118.0 0.2 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EER26250.1 - 7.5e-19 68.4 0.4 1.3e-18 67.6 0.4 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EER26250.1 - 2.5e-08 34.4 0.0 7.1e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 EER26250.1 - 0.0013 18.6 0.0 0.0038 17.1 0.0 1.8 1 0 0 1 1 1 1 GRAM domain BAR PF03114.18 EER26250.1 - 0.0015 18.2 0.1 0.003 17.2 0.1 1.4 1 0 0 1 1 1 1 BAR domain Sen15 PF09631.10 EER26251.1 - 1.7e-15 57.2 0.0 4.6e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 Sen15 protein UAA PF08449.11 EER26252.1 - 8.5e-46 156.5 6.5 2e-45 155.3 6.5 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EER26252.1 - 4.3e-09 36.7 26.5 4e-05 23.8 7.8 3.5 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.15 EER26252.1 - 1.3e-07 31.1 0.4 0.0025 17.1 0.0 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter Phage_holin_3_6 PF07332.11 EER26252.1 - 0.33 11.0 2.9 0.55 10.3 1.0 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Rotamase_3 PF13616.6 EER26253.1 - 1.2e-15 58.1 0.0 2.4e-15 57.1 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EER26253.1 - 3.5e-14 53.5 0.0 5.9e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EER26253.1 - 4.5e-05 24.3 0.1 5.7e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain 2OG-FeII_Oxy_2 PF13532.6 EER26254.1 - 2.7e-12 47.3 0.0 8.9e-11 42.3 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.16 EER26255.1 - 2.6e-08 34.0 0.1 6.3e-08 32.7 0.1 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3492 PF11997.8 EER26255.1 - 0.094 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Ank_5 PF13857.6 EER26256.1 - 1.7e-21 76.0 0.9 2.1e-08 34.3 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER26256.1 - 6.8e-21 74.6 0.0 7.7e-09 36.0 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER26256.1 - 4.6e-16 58.9 0.1 5.6e-07 30.0 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EER26256.1 - 8.6e-14 51.3 2.6 5.1e-05 23.5 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EER26256.1 - 4.1e-13 48.2 0.4 3.5e-05 23.8 0.0 4.2 5 0 0 5 5 5 3 Ankyrin repeat Ribosomal_L7Ae PF01248.26 EER26257.1 - 1.3e-26 92.1 0.8 1.7e-26 91.7 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EER26257.1 - 0.036 13.9 0.0 0.056 13.3 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Vac_ImportDeg PF09783.9 EER26258.1 - 6.8e-39 133.3 0.1 2.3e-38 131.5 0.0 1.8 2 0 0 2 2 2 1 Vacuolar import and degradation protein IU_nuc_hydro PF01156.19 EER26259.1 - 1.3e-80 271.2 0.1 1.6e-80 270.9 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase MaoC_dehydrat_N PF13452.6 EER26259.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase PXA PF02194.15 EER26260.1 - 4.1e-47 160.5 0.5 6.8e-47 159.8 0.5 1.4 1 0 0 1 1 1 1 PXA domain EccE PF11203.8 EER26260.1 - 0.067 13.5 0.4 9.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE HTH_Tnp_Tc5 PF03221.16 EER26262.1 - 8.4e-14 51.4 0.0 1.6e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EER26262.1 - 1.4e-06 27.8 0.0 3.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Crp_2 PF13545.6 EER26262.1 - 0.0069 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Crp-like helix-turn-helix domain MarR PF01047.22 EER26262.1 - 0.031 14.2 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 MarR family Sigma70_r4 PF04545.16 EER26262.1 - 0.082 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_37 PF13744.6 EER26262.1 - 0.13 12.2 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.6 EER26262.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 EER26262.1 - 0.15 11.9 0.0 0.43 10.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain MMR_HSR1_Xtn PF16897.5 EER26263.1 - 2e-41 140.3 0.9 1.9e-40 137.1 0.3 2.4 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EER26263.1 - 8.3e-24 83.4 0.1 2.7e-23 81.8 0.1 1.9 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 EER26263.1 - 1.4e-20 73.5 0.1 4.8e-20 71.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EER26263.1 - 1.2e-09 37.9 0.1 6e-09 35.6 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EER26263.1 - 0.0003 20.9 0.1 0.069 13.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 EER26263.1 - 0.00032 20.3 0.1 3.6 7.1 0.0 4.0 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 EER26263.1 - 0.0084 15.1 0.1 0.019 13.9 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EER26263.1 - 0.12 12.3 1.4 3.9 7.3 0.1 3.0 2 2 1 3 3 3 0 RsgA GTPase Ploopntkinase3 PF18751.1 EER26263.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CDO_I PF05995.12 EER26264.1 - 1.1e-42 145.2 0.0 1.3e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EER26264.1 - 3.5e-07 29.9 0.0 5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO Glyco_transf_90 PF05686.12 EER26265.1 - 5.2e-15 55.3 9.6 1.1e-12 47.6 8.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.7 EER26266.1 - 4.6e-18 66.6 0.6 8.1e-18 65.8 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER26266.1 - 2.1e-13 50.5 0.0 3.3e-11 43.3 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER26266.1 - 2.6e-08 33.4 0.0 3.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Glyco_transf_8 PF01501.20 EER26267.1 - 2.9e-21 76.2 0.0 6e-21 75.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 HEAT PF02985.22 EER26268.1 - 1.7e-40 133.6 15.4 0.015 15.5 0.1 13.3 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 EER26268.1 - 7.9e-37 125.5 1.6 8.5e-10 38.9 0.0 8.6 3 3 6 9 9 9 9 HEAT repeats HEAT_EZ PF13513.6 EER26268.1 - 6.7e-15 55.2 1.9 0.0079 16.7 0.0 8.3 8 2 1 9 9 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EER26268.1 - 5.4e-12 46.1 3.5 0.00094 19.7 0.1 7.4 5 2 4 10 10 10 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EER26268.1 - 8.1e-10 39.0 10.8 0.0016 18.5 0.1 6.0 5 2 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EER26268.1 - 2.6e-08 32.9 5.8 6.4e-07 28.3 1.3 3.7 3 1 1 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 EER26268.1 - 1.1e-05 25.5 5.2 0.94 9.7 0.1 5.0 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Proteasom_PSMB PF10508.9 EER26268.1 - 0.00075 18.1 3.5 0.4 9.1 1.0 2.4 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit Arm PF00514.23 EER26268.1 - 0.0012 18.8 3.2 1.5 8.9 0.0 5.1 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EER26268.1 - 0.022 14.3 2.8 3.6 7.1 0.1 4.2 4 1 1 5 5 5 0 CLASP N terminal Nop52 PF05997.12 EER26268.1 - 0.058 13.2 0.1 0.74 9.6 0.0 2.7 1 1 0 2 2 2 0 Nucleolar protein,Nop52 IFRD PF05004.13 EER26268.1 - 0.087 11.9 1.9 2 7.5 0.0 3.6 3 1 0 4 4 4 0 Interferon-related developmental regulator (IFRD) M11L PF11099.8 EER26268.1 - 0.21 11.8 0.4 53 4.1 0.0 3.3 2 1 1 3 3 3 0 Apoptosis regulator M11L like RhoGAP PF00620.27 EER26268.1 - 0.22 11.3 1.2 0.73 9.6 0.2 2.3 2 1 0 2 2 2 0 RhoGAP domain Ecm29 PF13001.7 EER26268.1 - 1.8 7.1 6.3 59 2.2 0.1 4.5 4 1 1 5 5 5 0 Proteasome stabiliser tRNA_synthFbeta PF17759.1 EER26269.1 - 9.6e-50 169.0 0.0 1.4e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EER26269.1 - 1.3e-33 115.0 0.3 3.1e-32 110.6 0.0 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EER26269.1 - 2e-24 86.2 0.0 4.4e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EER26269.1 - 4.3e-18 65.4 0.0 2.7e-16 59.6 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase B5 domain Ribosomal_S3_C PF00189.20 EER26270.1 - 1.1e-24 86.7 0.2 5.6e-24 84.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EER26270.1 - 6.4e-12 45.1 0.1 1.1e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EER26270.1 - 0.07 12.9 0.1 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 Coilin N-terminus UN_NPL4 PF11543.8 EER26270.1 - 0.099 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.14 EER26271.1 - 1.2e-150 501.3 0.0 1.5e-150 501.0 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EER26271.1 - 0.0017 18.4 0.1 0.015 15.3 0.1 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family HD_assoc PF13286.6 EER26271.1 - 0.027 15.0 0.1 0.067 13.7 0.1 1.6 1 1 0 1 1 1 0 Phosphohydrolase-associated domain GRAM PF02893.20 EER26271.1 - 0.17 11.8 0.1 0.8 9.6 0.0 2.2 2 1 0 2 2 2 0 GRAM domain SLS PF14611.6 EER26272.1 - 3.5e-33 115.3 0.0 5.3e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator GFRP PF06399.13 EER26272.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) NT-C2 PF10358.9 EER26273.1 - 2.4e-33 114.9 0.0 3.3e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins zf-C2H2_6 PF13912.6 EER26273.1 - 0.11 12.5 1.8 0.25 11.4 1.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger T3SSipB PF16535.5 EER26274.1 - 0.018 15.5 1.7 0.022 15.2 1.7 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB Cofac_haem_bdg PF04187.13 EER26274.1 - 0.1 12.6 1.9 0.12 12.3 1.9 1.1 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN PRKCSH-like PF12999.7 EER26274.1 - 0.32 10.8 2.1 0.42 10.4 2.1 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like TMPIT PF07851.13 EER26274.1 - 1.1 8.4 8.3 1.4 8.0 8.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF3074 PF11274.8 EER26276.1 - 2.1e-55 187.5 0.3 5.7e-55 186.1 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) CENP-F_leu_zip PF10473.9 EER26276.1 - 0.87 9.6 21.1 0.11 12.5 16.2 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 EER26276.1 - 1.7 9.1 7.6 14 6.1 1.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SF3b10 PF07189.11 EER26277.1 - 3.6e-35 119.9 0.0 4e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.18 EER26278.1 - 1.4e-23 83.9 1.1 1.3e-11 44.6 0.3 3.1 3 1 0 3 3 3 2 Adenosine-deaminase (editase) domain ERG4_ERG24 PF01222.17 EER26279.1 - 1.3e-146 488.7 3.2 1.6e-146 488.5 3.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EER26279.1 - 0.0016 18.0 0.1 0.0039 16.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ferlin_C PF16165.5 EER26279.1 - 0.15 12.0 1.7 0.37 10.7 1.7 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Kdo PF06293.14 EER26280.1 - 1.4e-06 27.8 0.0 3.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER26280.1 - 0.0084 16.1 1.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family ApoO PF09769.9 EER26280.1 - 0.0092 15.9 0.7 0.019 14.9 0.7 1.4 1 0 0 1 1 1 1 Apolipoprotein O HSDR_N_2 PF13588.6 EER26280.1 - 0.032 14.2 0.0 0.83 9.7 0.0 2.5 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Choline_kinase PF01633.20 EER26280.1 - 0.23 11.0 1.0 0.37 10.3 0.1 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase WD40 PF00400.32 EER26281.1 - 1.4e-06 28.9 0.2 1.4e-06 28.9 0.2 2.9 2 1 1 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER26281.1 - 0.088 13.1 0.0 0.2 12.0 0.0 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain APH PF01636.23 EER26282.1 - 1.6e-10 41.4 0.0 4.8e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family CIMR PF00878.18 EER26283.1 - 1.2e-06 28.6 0.1 0.00029 20.9 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Fungal_trans PF04082.18 EER26284.1 - 1.1e-21 77.0 0.0 2e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26284.1 - 8.1e-09 35.5 10.4 1.3e-08 34.8 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L12_N PF16320.5 EER26284.1 - 2.8 7.7 12.5 7.1 6.4 12.5 1.7 1 0 0 1 1 1 0 Ribosomal protein L7/L12 dimerisation domain Glyco_hydro_3_C PF01915.22 EER26285.1 - 3.3e-51 174.2 0.0 6.1e-51 173.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EER26285.1 - 1.6e-37 129.6 0.0 3.1e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EER26285.1 - 8.8e-15 54.6 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Pro-kuma_activ PF09286.11 EER26286.1 - 1.6e-35 122.5 0.1 3.2e-35 121.5 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EER26286.1 - 7.7e-06 25.4 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Lipase_GDSL_2 PF13472.6 EER26286.1 - 0.056 13.8 0.1 0.36 11.2 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF3262 PF11660.8 EER26287.1 - 0.18 12.2 0.1 0.18 12.2 0.1 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3262) Zn_clus PF00172.18 EER26288.1 - 0.0012 18.9 12.1 0.0023 18.0 12.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Scs3p PF10261.9 EER26289.1 - 1.7e-72 243.9 2.4 2.5e-72 243.4 2.4 1.3 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Erythro_esteras PF05139.14 EER26291.1 - 9.6e-129 430.1 3.1 1.1e-128 429.9 3.1 1.0 1 0 0 1 1 1 1 Erythromycin esterase Cofac_haem_bdg PF04187.13 EER26291.1 - 0.00011 22.3 1.4 0.091 12.7 0.1 2.2 2 0 0 2 2 2 2 Haem-binding uptake, Tiki superfamily, ChaN Mit_ribos_Mrp51 PF11709.8 EER26291.1 - 0.049 13.2 0.0 0.072 12.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit DUF3535 PF12054.8 EER26293.1 - 3.5e-124 415.4 0.0 5.3e-123 411.5 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EER26293.1 - 1.8e-61 207.8 0.0 1.9e-60 204.4 0.0 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER26293.1 - 3.8e-20 72.3 0.2 1.2e-19 70.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HEAT PF02985.22 EER26293.1 - 6.5e-14 50.9 12.4 0.17 12.2 0.0 10.1 12 0 0 12 12 12 4 HEAT repeat HEAT_2 PF13646.6 EER26293.1 - 3.8e-09 36.8 8.4 0.011 16.1 0.0 6.6 6 1 1 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EER26293.1 - 5.8e-07 30.0 0.2 0.23 12.1 0.1 4.4 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EER26293.1 - 0.00024 20.8 0.0 0.022 14.3 0.0 3.2 3 0 0 3 3 3 1 CLASP N terminal TAF6_C PF07571.13 EER26293.1 - 0.00027 21.2 0.0 0.54 10.6 0.0 5.1 6 0 0 6 6 6 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 EER26293.1 - 0.00076 19.9 11.5 12 6.6 0.0 7.4 7 0 0 7 7 7 1 HEAT-like repeat ERCC3_RAD25_C PF16203.5 EER26293.1 - 0.085 12.1 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ndufs5 PF10200.9 EER26294.1 - 0.015 15.5 0.0 0.017 15.3 0.0 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.13 EER26294.1 - 0.04 14.1 0.3 0.27 11.4 0.3 2.0 1 1 1 2 2 2 0 CHCH domain Sec39 PF08314.11 EER26295.1 - 1.5e-252 840.4 0.0 1.7e-252 840.2 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 MbeD_MobD PF04899.12 EER26295.1 - 0.036 14.2 1.8 0.044 13.9 0.1 2.0 2 0 0 2 2 2 0 MbeD/MobD like Pkinase PF00069.25 EER26296.1 - 3.9e-63 213.3 0.0 4.8e-63 213.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26296.1 - 3.6e-35 121.5 0.0 5.1e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER26296.1 - 1.4e-06 27.8 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EER26296.1 - 0.00019 20.3 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EER26296.1 - 0.21 11.2 0.0 6.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Protoglobin PF11563.8 EER26297.1 - 9.3e-51 171.9 0.0 1.1e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Methyltransf_23 PF13489.6 EER26301.1 - 8.1e-22 77.8 0.0 1.3e-21 77.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER26301.1 - 1.6e-11 44.7 0.0 4.7e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER26301.1 - 2.1e-08 34.7 0.0 4.5e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER26301.1 - 3.2e-08 33.5 0.0 3.7e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER26301.1 - 4.8e-07 30.4 0.0 2.9e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER26301.1 - 0.00047 19.7 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EER26301.1 - 0.0021 17.5 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EER26301.1 - 0.0085 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 EER26301.1 - 0.012 15.7 0.0 0.024 14.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EER26301.1 - 0.019 14.3 0.0 0.19 11.0 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EER26301.1 - 0.019 14.4 0.0 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.12 EER26301.1 - 0.029 14.1 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.19 EER26301.1 - 0.11 12.3 0.0 2.6 7.8 0.0 2.5 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4451 PF14616.6 EER26302.1 - 1.3e-23 83.6 0.2 2.1e-23 82.8 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Zn_ribbon_recom PF13408.6 EER26302.1 - 0.11 13.1 2.0 0.28 11.7 2.0 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain TPR_1 PF00515.28 EER26303.1 - 1e-40 135.9 15.0 4e-09 35.9 0.2 8.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 EER26303.1 - 4.8e-40 132.4 14.4 7.1e-08 32.0 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.31 EER26303.1 - 1.2e-27 95.8 3.4 1.2e-27 95.8 3.4 3.1 4 0 0 4 4 2 1 DnaJ domain TPR_19 PF14559.6 EER26303.1 - 5.1e-27 94.2 14.2 8.2e-07 29.4 0.1 6.6 3 3 4 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EER26303.1 - 4e-26 90.4 15.3 2.7e-06 26.9 0.0 7.2 5 2 3 8 8 8 5 TPR repeat TPR_8 PF13181.6 EER26303.1 - 1.9e-25 86.9 10.9 7.9e-06 25.7 0.1 7.5 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 EER26303.1 - 1.6e-21 76.6 7.4 5.4e-05 23.8 0.1 5.7 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EER26303.1 - 2.8e-21 73.9 7.0 0.00028 20.7 0.1 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EER26303.1 - 2.3e-20 71.5 10.7 6.3e-05 23.5 0.0 8.0 4 2 4 8 8 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 EER26303.1 - 1.9e-19 68.6 10.6 0.0046 17.2 0.2 7.0 7 0 0 7 7 6 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EER26303.1 - 1.2e-14 54.3 5.4 2.1e-06 27.9 0.2 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EER26303.1 - 7.7e-14 51.8 15.8 0.00046 20.4 0.4 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 EER26303.1 - 1.6e-13 50.5 4.4 0.0045 17.1 0.1 5.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_15 PF13429.6 EER26303.1 - 7.7e-10 38.4 6.1 0.0037 16.5 0.0 4.6 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 EER26303.1 - 9e-10 38.6 18.1 0.00014 22.2 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat ChAPs PF09295.10 EER26303.1 - 8.1e-07 28.4 0.2 0.0037 16.3 0.0 2.8 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 EER26303.1 - 3.3e-06 27.6 8.0 0.058 13.8 0.3 4.4 3 2 1 5 5 5 2 Bacterial transcriptional activator domain TPR_4 PF07721.14 EER26303.1 - 1.3e-05 25.4 0.2 4.6 8.2 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EER26303.1 - 4.2e-05 23.3 20.2 0.064 13.1 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_20 PF14561.6 EER26303.1 - 7.1e-05 23.1 6.5 2.8 8.4 0.3 4.6 3 2 1 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EER26303.1 - 7.2e-05 22.8 9.2 0.36 10.9 0.1 4.7 4 1 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat SRP_TPR_like PF17004.5 EER26303.1 - 0.00055 19.9 1.4 0.73 9.9 0.0 2.9 2 1 0 2 2 2 2 Putative TPR-like repeat TPR_MalT PF17874.1 EER26303.1 - 0.00063 19.2 1.0 0.32 10.3 0.2 3.2 2 1 0 2 2 2 1 MalT-like TPR region Alkyl_sulf_dimr PF14863.6 EER26303.1 - 0.0025 18.3 0.7 1 9.8 0.2 3.5 2 2 1 3 3 3 1 Alkyl sulfatase dimerisation SHNi-TPR PF10516.9 EER26303.1 - 0.0035 16.7 5.7 1.2 8.6 0.1 4.7 5 0 0 5 5 4 1 SHNi-TPR Coatomer_E PF04733.14 EER26303.1 - 0.036 13.5 1.2 6.9 6.0 0.0 2.9 2 1 0 3 3 3 0 Coatomer epsilon subunit DUF3808 PF10300.9 EER26303.1 - 0.054 12.2 0.1 0.93 8.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) HHH_8 PF14716.6 EER26303.1 - 0.067 13.6 4.4 19 5.7 0.2 4.3 4 0 0 4 4 3 0 Helix-hairpin-helix domain DUF4919 PF16266.5 EER26303.1 - 0.077 12.9 1.0 44 4.0 0.0 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4919) RPT PF13446.6 EER26303.1 - 0.11 12.5 0.8 1 9.3 0.1 2.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein MIT PF04212.18 EER26303.1 - 9.1 6.4 14.2 9.3 6.4 0.1 4.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain SelK_SelG PF10961.8 EER26304.1 - 0.03 14.9 0.0 0.068 13.8 0.0 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG HC2 PF07382.11 EER26305.1 - 0.0023 18.1 53.6 0.0042 17.2 53.6 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 MFS_1 PF07690.16 EER26306.1 - 5.8e-27 94.5 59.0 1.8e-23 83.0 30.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3188 PF11384.8 EER26306.1 - 0.21 11.3 2.7 1.7 8.4 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) S_4TM PF18159.1 EER26306.1 - 0.45 9.8 0.9 1.1 8.5 0.2 2.0 1 1 0 1 1 1 0 SMODS-associating 4TM effector domain DUF1772 PF08592.11 EER26306.1 - 8.9 6.6 10.7 12 6.2 5.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Pkinase PF00069.25 EER26307.1 - 1.8e-39 135.7 0.0 2.5e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26307.1 - 1.1e-28 100.3 0.0 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER26307.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Med10 PF09748.9 EER26308.1 - 2.1e-45 153.6 0.0 2.4e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 EER26308.1 - 0.008 16.1 0.1 0.019 14.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) NPV_P10 PF05531.12 EER26308.1 - 0.034 14.6 0.0 0.094 13.2 0.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Snapin_Pallidin PF14712.6 EER26308.1 - 0.042 14.3 0.2 20 5.7 0.0 2.7 3 0 0 3 3 3 0 Snapin/Pallidin Peptidase_M28 PF04389.17 EER26310.1 - 3.4e-34 118.3 0.0 5.5e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 F-box-like PF12937.7 EER26311.1 - 1.5e-11 44.0 1.5 3.1e-11 43.0 0.6 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 EER26311.1 - 2e-10 40.8 10.4 1.7 9.1 0.1 7.9 5 2 4 9 9 9 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EER26311.1 - 6e-10 38.4 25.4 0.68 10.1 0.0 12.0 14 0 0 14 14 14 3 Leucine Rich repeat F-box PF00646.33 EER26311.1 - 1.7e-05 24.6 4.4 3.6e-05 23.5 0.4 3.4 3 0 0 3 3 3 1 F-box domain DUF1699 PF08004.11 EER26311.1 - 5.1e-05 23.0 1.1 0.03 14.0 0.0 3.5 3 2 1 4 4 4 2 Protein of unknown function (DUF1699) AMP-binding PF00501.28 EER26312.1 - 2e-73 247.4 0.0 2.3e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER26312.1 - 4e-16 59.8 0.1 1.8e-15 57.6 0.1 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Ribosomal_L13 PF00572.18 EER26313.1 - 9.8e-12 45.2 0.1 9.8e-10 38.8 0.0 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 Metallophos PF00149.28 EER26314.1 - 3.7e-15 57.0 0.2 7e-15 56.1 0.2 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EER26314.1 - 7.2e-09 36.0 0.0 6.2e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EER26314.1 - 0.00014 21.3 0.0 0.001 18.4 0.0 2.0 2 0 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily DnaJ PF00226.31 EER26315.1 - 3.3e-23 81.6 1.7 7.4e-23 80.5 1.7 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4470 PF14737.6 EER26316.1 - 3.2e-25 88.2 0.1 5.8e-25 87.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EER26316.1 - 4.4e-08 33.1 12.0 1.1e-07 31.9 12.0 1.7 1 0 0 1 1 1 1 MYND finger PHD PF00628.29 EER26316.1 - 10 6.1 9.4 5.3 7.0 5.3 2.5 2 0 0 2 2 2 0 PHD-finger APH PF01636.23 EER26317.1 - 3.1e-12 46.9 0.3 1.3e-11 44.9 0.3 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EER26317.1 - 0.0016 17.9 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain RIO1 PF01163.22 EER26317.1 - 0.002 17.8 0.0 0.0082 15.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.20 EER26317.1 - 0.0047 16.5 0.0 0.0069 16.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EER26317.1 - 0.17 10.7 0.0 2.9 6.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.25 EER26318.1 - 8.9e-07 28.5 0.0 1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26318.1 - 0.2 10.9 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase EamA PF00892.20 EER26319.1 - 7e-11 42.4 17.3 7e-05 23.0 10.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EER26319.1 - 7.3e-08 31.9 1.2 1.4e-07 31.0 1.2 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EER26319.1 - 0.00012 21.4 8.7 0.00015 21.1 7.8 1.6 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.16 EER26319.1 - 0.0003 20.2 3.7 0.004 16.5 0.1 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family TrbC PF04956.13 EER26319.1 - 0.0094 16.1 4.3 0.3 11.3 0.9 3.1 2 0 0 2 2 2 1 TrbC/VIRB2 family Neurensin PF14927.6 EER26319.1 - 2.2 8.0 5.7 6.8 6.4 0.5 2.9 2 1 0 2 2 2 0 Neurensin Beta-lactamase PF00144.24 EER26320.1 - 4.1e-50 170.9 0.0 1e-48 166.3 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EER26320.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase MBOAT PF03062.19 EER26321.1 - 3.1e-10 40.0 15.9 5.4e-07 29.3 3.6 3.2 1 1 1 3 3 3 3 MBOAT, membrane-bound O-acyltransferase family Fumarate_red_D PF02313.17 EER26321.1 - 0.009 16.1 5.6 0.009 16.1 5.6 2.4 2 1 0 2 2 2 1 Fumarate reductase subunit D Adaptin_N PF01602.20 EER26322.1 - 4.2e-142 474.4 0.5 5e-142 474.1 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EER26322.1 - 5.9e-21 74.9 0.1 5.9e-21 74.9 0.1 2.4 2 1 1 3 3 3 1 Adaptin C-terminal domain Cnd1 PF12717.7 EER26322.1 - 9.1e-07 29.1 5.4 0.00078 19.5 0.0 4.2 2 2 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EER26322.1 - 6.8e-06 26.4 0.2 0.017 15.5 0.0 3.6 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EER26322.1 - 0.033 14.5 2.4 41 4.8 0.1 4.4 4 0 0 4 4 4 0 HEAT repeat Peptidase_M73 PF12389.8 EER26322.1 - 0.084 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase RICTOR_M PF14666.6 EER26322.1 - 0.091 12.5 0.6 0.72 9.7 0.0 2.5 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain GCP_C_terminal PF04130.13 EER26323.1 - 7.1e-102 341.0 0.0 1.4e-101 340.1 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EER26323.1 - 3.4e-78 263.4 0.0 2.3e-77 260.7 0.0 2.1 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF2373 PF10180.9 EER26324.1 - 1.3e-17 63.3 0.0 2.6e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.26 EER26325.1 - 6.2e-50 169.3 0.0 8.7e-50 168.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EER26325.1 - 4.4e-13 48.6 0.3 8.3e-13 47.8 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PTR2 PF00854.21 EER26327.1 - 8.9e-95 317.8 4.3 1.8e-94 316.8 4.3 1.4 1 1 0 1 1 1 1 POT family Chordopox_L2 PF05803.12 EER26327.1 - 0.12 12.2 0.3 0.36 10.7 0.3 1.8 1 0 0 1 1 1 0 Chordopoxvirus L2 protein Glyco_hydro_18 PF00704.28 EER26328.1 - 1e-80 271.8 0.2 1.2e-80 271.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.23 EER26329.1 - 5.1e-34 115.9 0.7 9.7e-34 115.0 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EER26329.1 - 2e-26 91.9 2.4 2e-26 91.9 2.4 2.0 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EER26329.1 - 3.5e-16 58.8 0.8 7.4e-16 57.7 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EER26329.1 - 3.1e-05 24.4 0.6 0.00013 22.4 0.2 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EER26329.1 - 0.00074 19.6 0.8 0.0017 18.5 0.8 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EER26329.1 - 0.0059 16.5 0.0 0.009 15.9 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EER26329.1 - 0.0081 16.5 1.1 0.013 15.9 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DUF2407 PF10302.9 EER26329.1 - 0.01 16.4 1.0 0.014 15.9 1.0 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EER26329.1 - 0.022 14.8 1.1 6.1 7.0 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain DUF971 PF06155.12 EER26329.1 - 0.051 14.2 0.1 0.094 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF971) zf-C2H2 PF00096.26 EER26330.1 - 2.3e-07 30.9 20.3 0.035 14.6 0.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER26330.1 - 2.8e-06 27.5 14.8 0.00081 19.7 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER26330.1 - 1.1e-05 25.9 18.1 0.2 12.6 6.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EER26330.1 - 6 6.7 9.6 22 4.9 3.9 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF155 PF02582.14 EER26331.1 - 2.2e-48 164.7 0.0 3e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.20 EER26332.1 - 2.3e-19 69.7 1.7 9e-17 61.3 0.1 3.9 4 0 0 4 4 4 1 Region in Clathrin and VPS PQQ_3 PF13570.6 EER26332.1 - 0.0041 17.5 0.8 0.017 15.6 0.2 2.5 2 0 0 2 2 2 1 PQQ-like domain BUD22 PF09073.10 EER26332.1 - 0.0047 16.3 5.5 0.0085 15.5 5.5 1.3 1 0 0 1 1 1 1 BUD22 BSP_II PF05432.11 EER26332.1 - 0.049 13.3 13.4 0.1 12.3 13.4 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) zf-RING_5 PF14634.6 EER26332.1 - 0.067 13.2 0.6 0.19 11.7 0.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain TRAP_alpha PF03896.16 EER26332.1 - 0.33 10.1 5.1 0.59 9.3 5.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FYDLN_acid PF09538.10 EER26332.1 - 0.85 10.3 23.6 2.5 8.8 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 EER26332.1 - 2.3 7.9 10.4 5.9 6.5 10.4 1.6 1 0 0 1 1 1 0 FAM176 family GOLD_2 PF13897.6 EER26332.1 - 3.4 8.2 4.9 2.3 8.7 2.4 2.0 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF913 PF06025.12 EER26332.1 - 3.9 6.4 6.1 7.4 5.4 6.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DNA_pol_phi PF04931.13 EER26332.1 - 5.7 4.9 20.9 8.7 4.3 20.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 EER26332.1 - 6.5 6.8 10.5 14 5.7 10.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal SAP130_C PF16014.5 EER26333.1 - 0.035 13.2 17.0 0.043 12.9 17.0 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus CP2 PF04516.15 EER26334.1 - 1.9e-80 269.4 0.0 3e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor CclA_1 PF16942.5 EER26335.1 - 0.0027 17.9 0.4 0.0027 17.9 0.4 2.2 2 0 0 2 2 2 1 Putative cyclic bacteriocin TNFR_16_TM PF18422.1 EER26335.1 - 0.9 9.6 5.6 0.14 12.1 1.1 2.1 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain Metallopep PF12044.8 EER26336.1 - 7.8e-138 459.7 0.0 1e-137 459.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Tom5 PF10642.9 EER26336.1 - 0.054 13.5 0.2 0.59 10.2 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase GST_C_2 PF13410.6 EER26338.1 - 4.7e-07 29.7 0.5 8.8e-07 28.9 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EER26338.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EER26338.1 - 0.0023 18.2 0.0 0.0055 17.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EER26338.1 - 0.0028 17.8 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EER26338.1 - 0.0077 17.0 0.0 0.016 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 EER26338.1 - 0.0094 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DJ-1_PfpI PF01965.24 EER26339.1 - 2.6e-12 46.9 0.0 5.3e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EER26339.1 - 0.0008 19.1 0.1 0.0023 17.6 0.1 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like Binary_toxB PF03495.14 EER26339.1 - 0.13 12.4 0.2 0.29 11.4 0.2 1.6 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DNA_ligase_A_M PF01068.21 EER26340.1 - 1.5e-52 178.2 0.0 5.7e-50 169.8 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EER26340.1 - 4.3e-37 128.1 0.0 8e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EER26340.1 - 1.2e-22 80.4 0.0 3.8e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region NuDC PF16273.5 EER26340.1 - 0.1 13.1 0.9 0.35 11.4 0.9 1.9 1 0 0 1 1 1 0 Nuclear distribution C domain Abhydrolase_9 PF10081.9 EER26340.1 - 0.15 11.2 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family RINT1_TIP1 PF04437.13 EER26341.1 - 6.3e-178 592.7 1.4 2.4e-177 590.8 0.0 2.1 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Nup54 PF13874.6 EER26341.1 - 0.025 14.7 6.9 0.064 13.4 6.9 1.7 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 Uso1_p115_C PF04871.13 EER26341.1 - 0.026 14.9 11.5 0.29 11.5 12.6 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TBCC_N PF16752.5 EER26341.1 - 0.23 11.9 10.9 0.68 10.4 10.9 1.8 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain ECH_1 PF00378.20 EER26341.1 - 0.41 9.9 4.4 1.1 8.5 4.4 1.7 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Peptidase_C65 PF10275.9 EER26341.1 - 0.56 9.6 3.3 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Peptidase C65 Otubain Exonuc_VII_L PF02601.15 EER26341.1 - 1.2 8.6 5.8 2.7 7.5 5.8 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fib_alpha PF08702.10 EER26341.1 - 1.8 8.7 6.9 5.3 7.2 6.9 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pyridoxal_deC PF00282.19 EER26342.1 - 3.3e-80 269.6 0.0 4e-80 269.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EER26342.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EER26342.1 - 2e-07 30.3 0.0 2.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PUF PF00806.19 EER26343.1 - 1.4e-16 59.2 0.0 0.39 10.5 0.0 7.4 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat Y_phosphatase PF00102.27 EER26344.1 - 4.3e-50 170.5 0.0 1e-49 169.3 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EER26344.1 - 0.0025 17.6 0.1 0.009 15.8 0.1 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EER26344.1 - 0.0037 17.2 0.0 0.0068 16.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EER26344.1 - 0.0074 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate VanZ PF04892.12 EER26345.1 - 3.6e-08 34.1 0.3 5.4e-08 33.6 0.3 1.3 1 0 0 1 1 1 1 VanZ like family DUF4345 PF14248.6 EER26345.1 - 0.077 12.9 0.1 0.15 12.0 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) DUF4131 PF13567.6 EER26345.1 - 7.5 6.2 6.0 35 4.0 1.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Bromodomain PF00439.25 EER26346.1 - 2.1e-18 66.2 0.2 2.1e-18 66.2 0.2 2.1 3 0 0 3 3 3 1 Bromodomain Bromo_TP PF07524.13 EER26346.1 - 6e-09 35.8 0.0 2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated DUF3947 PF13135.6 EER26346.1 - 0.87 9.8 5.2 2.3 8.5 5.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) SPARC_Ca_bdg PF10591.9 EER26346.1 - 1.2 9.4 4.6 2.8 8.3 3.2 2.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Piwi PF02171.17 EER26347.1 - 7.7e-71 238.8 0.0 1e-70 238.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EER26347.1 - 3.2e-22 79.6 0.0 8.5e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EER26347.1 - 6.8e-17 60.9 0.8 2e-16 59.4 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 1 domain PAZ PF02170.22 EER26347.1 - 8.1e-12 45.1 0.3 1.7e-11 44.1 0.3 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EER26347.1 - 9.9e-11 41.8 0.0 2.5e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EER26347.1 - 6.7e-09 36.0 0.0 1.5e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Suf PF05843.14 EER26348.1 - 3.4e-96 322.7 0.0 3.4e-96 322.7 0.0 4.7 5 2 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EER26348.1 - 2.3e-08 34.2 0.4 0.028 15.2 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EER26348.1 - 0.0035 17.8 0.0 3.9 8.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.16 EER26348.1 - 0.012 15.5 0.3 0.012 15.5 0.3 2.5 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat TPR_16 PF13432.6 EER26348.1 - 0.024 15.3 0.0 4.2 8.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 EER26349.1 - 1.8e-74 248.8 0.0 2.5e-74 248.4 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 EER26349.1 - 0.79 7.9 16.8 1 7.5 16.8 1.0 1 0 0 1 1 1 0 Nop14-like family Lgl_C PF08596.10 EER26350.1 - 5.9e-122 407.1 0.0 9.7e-122 406.4 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EER26350.1 - 3e-06 27.4 0.0 2.3 8.6 0.0 5.3 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EER26350.1 - 0.0064 17.3 6.5 0.071 14.0 0.4 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat GMC_oxred_C PF05199.13 EER26350.1 - 0.16 12.5 0.0 0.61 10.6 0.0 1.9 2 0 0 2 2 2 0 GMC oxidoreductase APH PF01636.23 EER26351.1 - 4.1e-05 23.6 0.0 6.5e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.17 EER26352.1 - 4.9e-12 46.2 0.0 9.1e-12 45.3 0.0 1.4 1 1 0 1 1 1 1 THUMP domain TPP_enzyme_N PF02776.18 EER26353.1 - 3e-32 111.6 0.0 4.8e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EER26353.1 - 2.4e-21 75.9 0.0 5.5e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EER26353.1 - 1.8e-16 60.3 0.0 4.1e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.25 EER26354.1 - 3.9e-63 213.3 0.0 5.7e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26354.1 - 9e-45 153.0 0.0 1.4e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER26354.1 - 9e-14 51.5 0.0 1.9e-09 37.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EER26354.1 - 0.0046 15.8 2.9 0.0049 15.7 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 EER26354.1 - 0.0053 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER26354.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec34 PF04136.15 EER26355.1 - 5.2e-53 178.9 0.7 5.2e-53 178.9 0.7 2.2 3 0 0 3 3 3 1 Sec34-like family Exo70 PF03081.15 EER26355.1 - 0.0014 17.7 0.9 0.011 14.8 0.0 2.5 3 0 0 3 3 3 1 Exo70 exocyst complex subunit FUSC PF04632.12 EER26355.1 - 4.5 5.7 5.8 17 3.8 3.7 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Mid2 PF04478.12 EER26356.1 - 2.7e-07 30.5 0.0 6e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Syndecan PF01034.20 EER26356.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Rod_cone_degen PF15201.6 EER26356.1 - 0.031 14.4 2.0 0.052 13.7 0.0 2.5 2 0 0 2 2 2 0 Progressive rod-cone degeneration Tad PF13400.6 EER26356.1 - 0.47 10.8 5.5 0.44 10.9 0.9 2.2 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like SOG2 PF10428.9 EER26356.1 - 0.71 9.0 18.7 1.1 8.4 18.7 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 EER26356.1 - 0.75 8.6 4.3 0.75 8.6 4.3 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ndc1_Nup PF09531.10 EER26356.1 - 4.5 5.8 7.5 5.1 5.7 7.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase PF00069.25 EER26357.1 - 1.7e-10 40.7 0.0 2.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26357.1 - 1.4e-06 27.8 0.0 2.6e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER26357.1 - 1.7e-06 28.1 0.6 5e-05 23.3 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EER26357.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EER26357.1 - 0.008 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EER26357.1 - 0.011 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EER26357.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EER26357.1 - 0.02 14.2 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Gemin7 PF11095.8 EER26357.1 - 0.067 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Snurportin1 PF11538.8 EER26358.1 - 0.059 13.6 0.7 0.059 13.6 0.7 1.9 2 0 0 2 2 2 0 Snurportin1 DUF3752 PF12572.8 EER26358.1 - 0.069 13.7 7.9 0.068 13.7 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) Pex19 PF04614.12 EER26359.1 - 5.9e-51 173.6 7.6 5.9e-51 173.6 7.6 2.0 2 0 0 2 2 2 1 Pex19 protein family Cu_amine_oxid PF01179.20 EER26360.1 - 5.3e-164 546.0 0.0 6.9e-164 545.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EER26360.1 - 1.1e-06 28.7 0.1 2.1e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EER26360.1 - 2.1e-06 28.1 0.0 4.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain bZIP_1 PF00170.21 EER26361.1 - 1.3e-05 25.2 8.6 2.5e-05 24.3 8.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EER26361.1 - 3.4 7.8 14.5 0.15 12.2 8.8 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Stm1_N PF09598.10 EER26362.1 - 9.1e-13 48.9 8.6 9.1e-13 48.9 8.6 4.0 2 2 0 2 2 2 1 Stm1 HABP4_PAI-RBP1 PF04774.15 EER26362.1 - 0.0045 17.8 16.2 0.0045 17.8 16.2 2.5 1 1 1 2 2 2 1 Hyaluronan / mRNA binding family DUF1793 PF08760.11 EER26363.1 - 4.8e-69 232.0 0.1 7.8e-69 231.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EER26363.1 - 9.9e-65 217.4 0.2 3.3e-51 173.4 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EER26363.1 - 3.6e-41 141.4 0.0 5.5e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 EER26363.1 - 0.00093 18.7 0.1 0.0026 17.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) tRNA-synt_1c PF00749.21 EER26364.1 - 7.3e-106 353.6 0.0 1e-105 353.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EER26364.1 - 2.6e-40 138.2 0.3 5.1e-40 137.2 0.3 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 EER26364.1 - 0.00047 20.3 0.0 0.0099 16.1 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EER26364.1 - 0.00048 20.3 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EER26364.1 - 0.00049 20.1 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EER26364.1 - 0.011 15.1 0.7 0.029 13.7 0.7 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain GluRS_N PF18466.1 EER26364.1 - 0.037 14.4 0.0 0.098 13.1 0.0 1.8 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain SeqA_N PF17206.3 EER26366.1 - 0.081 12.2 1.2 0.15 11.4 1.2 1.4 1 0 0 1 1 1 0 SeqA protein N-terminal domain DUF4748 PF15932.5 EER26366.1 - 4.9 7.0 6.6 12 5.7 6.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DEAD PF00270.29 EER26367.1 - 4.5e-40 137.3 0.0 7.2e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26367.1 - 1.3e-29 102.7 0.0 4e-29 101.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER26367.1 - 1e-06 28.9 0.0 1.8e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EER26367.1 - 0.018 13.8 0.0 0.041 12.6 0.0 1.5 1 1 1 2 2 2 0 SNF2 family N-terminal domain HCO3_cotransp PF00955.21 EER26368.1 - 3.8e-86 289.9 13.8 2.9e-46 158.4 6.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family SF1-HH PF16275.5 EER26369.1 - 8.5e-43 145.3 1.0 1.8e-42 144.2 1.0 1.6 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EER26369.1 - 1.4e-11 43.9 11.1 2e-05 24.5 3.6 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EER26369.1 - 1.9e-08 34.0 0.1 3.5e-08 33.2 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EER26369.1 - 2.1e-06 27.6 6.2 0.0013 18.6 2.9 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EER26369.1 - 0.00049 19.8 4.7 0.27 11.0 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EER26369.1 - 0.0019 18.0 7.7 0.42 10.5 1.1 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EER26369.1 - 0.022 14.6 0.6 0.022 14.6 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 EER26369.1 - 0.67 10.4 6.8 4.9 7.6 0.5 3.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G Prim_Zn_Ribbon PF08273.12 EER26369.1 - 4.3 7.7 7.4 0.73 10.2 3.0 2.0 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase GST_N_3 PF13417.6 EER26370.1 - 1.9e-15 57.0 0.0 3.3e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EER26370.1 - 9.6e-14 51.5 0.0 1.6e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EER26370.1 - 6.2e-12 45.6 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EER26370.1 - 1e-10 41.7 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EER26370.1 - 8.8e-10 38.7 0.0 2e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EER26370.1 - 5.4e-08 32.7 0.0 1.4e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NAD_binding_6 PF08030.12 EER26371.1 - 1.5e-21 77.1 0.0 2.4e-19 70.0 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EER26371.1 - 3.2e-19 69.3 11.6 3.2e-19 69.3 11.6 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EER26371.1 - 6.9e-14 51.9 0.0 1.1e-11 44.8 0.0 2.7 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.21 EER26371.1 - 0.036 14.7 0.0 0.071 13.8 0.0 1.5 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4964 PF16334.5 EER26371.1 - 0.055 13.0 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) CLU PF13236.6 EER26373.1 - 2.5e-73 246.5 0.0 4.2e-73 245.8 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EER26373.1 - 6e-56 189.2 0.0 1.4e-55 188.0 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EER26373.1 - 2.6e-26 91.7 6.6 5.8e-12 45.7 0.1 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 EER26373.1 - 5.5e-25 87.5 0.3 1.4e-24 86.3 0.3 1.8 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EER26373.1 - 1.3e-21 75.7 1.9 3e-05 23.7 0.0 5.4 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EER26373.1 - 0.00034 20.5 1.6 0.14 12.3 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 EER26373.1 - 0.00043 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_8 PF13181.6 EER26373.1 - 0.0018 18.3 4.6 0.04 14.1 0.5 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EER26373.1 - 2.6 8.6 4.7 64 4.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 EER26374.1 - 5.3e-09 36.7 0.2 1.3e-08 35.4 0.2 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EER26374.1 - 0.0045 16.5 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 EER26374.1 - 0.0067 16.1 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.13 EER26374.1 - 0.0077 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.6 EER26374.1 - 0.011 15.3 0.0 0.053 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EER26374.1 - 0.035 14.4 0.3 0.79 10.0 0.2 2.6 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EER26374.1 - 0.037 13.9 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 EER26374.1 - 0.069 13.1 0.0 0.22 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ras PF00071.22 EER26376.1 - 1.9e-56 190.1 0.0 2.3e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER26376.1 - 2.3e-34 118.2 0.0 3.5e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER26376.1 - 9.8e-14 51.2 0.0 1.8e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EER26376.1 - 0.00015 21.8 0.0 0.00024 21.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER26376.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EER26376.1 - 0.0002 20.8 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EER26376.1 - 0.0009 19.7 0.1 0.0012 19.3 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EER26376.1 - 0.088 12.7 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase XFP_N PF09364.10 EER26377.1 - 2.7e-149 497.0 0.0 3.5e-149 496.6 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EER26377.1 - 1.9e-78 262.6 0.0 3e-78 261.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EER26377.1 - 1.9e-73 245.9 0.0 2.9e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EER26377.1 - 0.0017 18.2 0.2 0.0038 17.0 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.17 EER26378.1 - 2.2e-87 293.3 0.0 2.5e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Ribosomal_S7e PF01251.18 EER26379.1 - 1.3e-79 266.3 0.0 1.5e-79 266.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 EER26380.1 - 1.7e-144 482.2 0.0 2.1e-144 481.9 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family GP68 PF17469.2 EER26380.1 - 0.082 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Phage protein Gp68 Methyltransf_23 PF13489.6 EER26381.1 - 5e-09 36.2 0.0 7.8e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER26381.1 - 1.7e-08 35.0 0.0 4.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER26381.1 - 5.1e-05 23.9 0.0 0.00025 21.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER26381.1 - 9.8e-05 23.0 0.0 0.00024 21.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER26381.1 - 0.0037 17.1 0.0 0.019 14.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain P16-Arc PF04699.14 EER26382.1 - 2.8e-46 157.7 0.0 3.3e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Secretin_N PF03958.17 EER26382.1 - 0.32 11.4 1.7 4.5 7.7 1.6 2.2 1 1 0 1 1 1 0 Bacterial type II/III secretion system short domain Cation_ATPase_C PF00689.21 EER26383.1 - 8e-48 162.5 7.9 8e-48 162.5 7.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EER26383.1 - 7.5e-37 126.6 0.2 7.5e-37 126.6 0.2 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EER26383.1 - 4.3e-22 78.0 0.1 9.2e-22 76.9 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EER26383.1 - 1.9e-17 64.3 0.2 9.8e-17 61.9 0.2 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EER26383.1 - 5.9e-07 29.1 0.5 2.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EER26383.1 - 0.00041 20.2 0.0 0.0065 16.2 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1774 PF08611.10 EER26383.1 - 0.16 12.3 0.1 0.16 12.3 0.1 2.8 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) WD40 PF00400.32 EER26384.1 - 5.7e-30 102.9 7.4 5.5e-06 27.0 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat F-box-like PF12937.7 EER26384.1 - 9.3e-10 38.3 0.1 1.8e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 EER26384.1 - 9.8e-05 22.0 0.0 0.034 13.7 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.21 EER26384.1 - 0.00016 21.4 0.1 3.1 7.9 0.0 3.5 3 0 0 3 3 3 2 PQQ enzyme repeat F-box PF00646.33 EER26384.1 - 0.00018 21.3 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EER26384.1 - 0.0013 19.0 0.1 16 5.9 0.0 4.3 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EER26384.1 - 0.015 14.6 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 WD40-like domain BBS2_Mid PF14783.6 EER26384.1 - 0.017 15.2 0.1 12 6.0 0.1 3.6 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region F-box_4 PF15966.5 EER26384.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box Peptidase_S8 PF00082.22 EER26385.1 - 5.8e-25 88.2 15.0 1.8e-24 86.6 14.9 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER26385.1 - 2.5e-11 44.1 0.0 4.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 EB1 PF03271.17 EER26386.1 - 5.9e-17 61.6 1.6 1.1e-16 60.7 1.6 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EER26386.1 - 6.3e-06 26.3 0.2 1.1e-05 25.6 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 EER26386.1 - 6.9e-05 21.6 0.0 0.00013 20.6 0.0 1.4 2 0 0 2 2 2 1 Herpesvirus UL6 like Adeno_E3_CR2 PF02439.15 EER26387.1 - 0.054 13.3 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CPSF100_C PF13299.6 EER26388.1 - 7.5 6.7 10.0 25 5.0 10.0 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal ING PF12998.7 EER26389.1 - 2.5e-09 37.6 0.1 5.4e-09 36.6 0.1 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EER26389.1 - 5.2e-06 26.2 10.4 1e-05 25.3 10.4 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EER26389.1 - 0.43 10.9 4.2 1.5 9.2 4.2 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain Imm5 PF14423.6 EER26390.1 - 0.028 14.7 1.6 0.035 14.3 0.4 1.7 2 0 0 2 2 2 0 Immunity protein Imm5 Forkhead PF00250.18 EER26391.1 - 6.3e-34 116.1 1.1 1.1e-33 115.4 1.1 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EER26391.1 - 3e-07 30.7 0.0 5.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 EER26391.1 - 0.069 13.5 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 linker histone H1 and H5 family zf-C2H2 PF00096.26 EER26392.1 - 8e-06 26.0 18.2 4.4e-05 23.7 2.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER26392.1 - 3.5e-05 24.0 3.3 3.5e-05 24.0 3.3 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER26392.1 - 0.00015 22.4 1.7 0.00015 22.4 1.7 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EER26392.1 - 0.00068 19.9 3.1 0.002 18.4 3.1 1.9 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 EER26392.1 - 0.0021 18.3 0.7 0.005 17.1 0.7 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EER26392.1 - 0.0051 16.8 1.3 0.011 15.7 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger TFIIA PF03153.13 EER26392.1 - 0.059 13.4 67.3 0.12 12.3 50.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-TRAF PF02176.18 EER26392.1 - 1.1 10.0 6.4 0.31 11.7 2.2 2.1 2 0 0 2 2 2 0 TRAF-type zinc finger Fungal_trans PF04082.18 EER26393.1 - 3.9e-25 88.4 0.0 8.6e-25 87.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26393.1 - 8.5e-11 41.8 12.4 1.5e-10 41.0 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EER26393.1 - 0.086 13.0 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 Gal4-like dimerisation domain Sugar_tr PF00083.24 EER26394.1 - 8.8e-106 354.5 17.1 1e-105 354.3 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER26394.1 - 2.7e-20 72.6 30.4 2.7e-20 72.6 30.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EER26395.1 - 3.9e-06 25.9 0.0 6.9e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAF20 PF17052.5 EER26395.1 - 0.13 12.4 2.7 0.29 11.3 2.7 1.6 1 0 0 1 1 1 0 Cap associated factor TFIIE-A_C PF11521.8 EER26395.1 - 0.57 10.5 2.8 9.2 6.6 0.2 2.5 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha PHD PF00628.29 EER26397.1 - 8.6e-11 41.6 8.7 1.7e-10 40.6 8.7 1.5 1 0 0 1 1 1 1 PHD-finger APH PF01636.23 EER26397.1 - 0.0046 16.9 0.0 0.016 15.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER26397.1 - 0.16 11.6 0.0 0.4 10.2 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Presenilin PF01080.17 EER26397.1 - 2.6 6.7 3.1 4.2 6.0 3.1 1.4 1 0 0 1 1 1 0 Presenilin Med31 PF05669.12 EER26399.1 - 5e-32 109.8 0.1 6.3e-32 109.4 0.1 1.1 1 0 0 1 1 1 1 SOH1 HSP20 PF00011.21 EER26400.1 - 1.9e-17 63.3 1.8 4.8e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EER26400.1 - 1.5e-07 30.9 0.1 0.0022 17.5 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Xan_ur_permease PF00860.20 EER26401.1 - 1.6e-24 86.3 28.6 3e-22 78.9 27.6 3.0 2 1 0 2 2 2 2 Permease family Ldr_toxin PF13940.6 EER26401.1 - 3.3 7.8 6.2 34 4.6 1.0 3.2 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system Pal1 PF08316.11 EER26402.1 - 4.5e-46 157.0 1.4 2.5e-44 151.4 1.4 2.7 1 1 0 1 1 1 1 Pal1 cell morphology protein DASH_Dad3 PF08656.10 EER26403.1 - 6.4e-30 103.0 1.9 7.6e-30 102.8 1.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Peptidase_M75 PF09375.10 EER26403.1 - 0.063 12.7 0.2 0.071 12.6 0.2 1.1 1 0 0 1 1 1 0 Imelysin MAGE PF01454.19 EER26404.1 - 3.5e-61 206.6 0.0 6.5e-61 205.7 0.0 1.5 1 0 0 1 1 1 1 MAGE family DUF2997 PF11211.8 EER26404.1 - 0.18 11.6 0.3 0.35 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2997) TFIIE-A_C PF11521.8 EER26404.1 - 1.7 9.0 5.4 0.44 10.9 1.0 2.2 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ank_3 PF13606.6 EER26405.1 - 2.6e-10 39.6 0.1 0.0025 18.2 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EER26405.1 - 5.9e-08 33.2 0.0 2.5e-07 31.2 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER26405.1 - 1.2e-07 31.9 0.1 0.071 13.5 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EER26405.1 - 1.3e-07 32.0 0.3 8.5e-05 23.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EER26405.1 - 4.8e-07 30.0 0.0 0.0058 17.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat GP67 PF17634.2 EER26405.1 - 0.045 14.1 0.1 0.095 13.1 0.1 1.5 1 0 0 1 1 1 0 Gene product 67 TFIIS_C PF01096.18 EER26406.1 - 7.5e-19 67.3 2.2 7.5e-19 67.3 2.2 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EER26406.1 - 2.3e-06 27.3 7.3 5.9e-05 22.9 3.9 3.3 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 EER26406.1 - 0.00025 21.2 3.9 0.31 11.3 0.2 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 EER26406.1 - 0.025 14.6 6.0 0.14 12.1 1.0 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Root_cap PF06830.11 EER26406.1 - 0.056 13.6 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Root cap Zn_ribbon_recom PF13408.6 EER26406.1 - 0.1 13.1 2.0 2.5 8.7 0.4 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_4 PF13717.6 EER26406.1 - 0.21 11.5 9.6 1.8 8.6 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain C1_4 PF07975.12 EER26406.1 - 0.27 11.5 3.1 1.1 9.6 0.2 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain zf-Mss51 PF13824.6 EER26406.1 - 0.53 10.4 2.9 1.2 9.3 0.1 2.3 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 GTP_EFTU PF00009.27 EER26407.1 - 1.6e-55 187.7 0.0 2.4e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EER26407.1 - 2.9e-42 143.5 0.0 6.5e-42 142.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EER26407.1 - 6e-14 52.2 1.1 1.9e-13 50.6 1.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EER26407.1 - 0.0021 18.1 0.1 0.021 14.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EER26407.1 - 0.041 13.8 0.7 0.041 13.8 0.7 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 CDH PF02611.15 EER26407.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Chalcone_2 PF16035.5 EER26408.1 - 8.6e-76 254.3 0.0 1.1e-75 253.9 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EER26408.1 - 0.16 12.1 0.1 0.31 11.1 0.1 1.5 1 1 0 1 1 1 0 Chalcone isomerase-like Glutaredoxin PF00462.24 EER26409.1 - 1.1e-19 70.4 0.0 1.5e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EER26409.1 - 0.0084 16.6 0.1 0.013 15.9 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EER26409.1 - 0.01 16.2 0.0 0.015 15.7 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 EER26409.1 - 0.019 15.0 0.0 0.02 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.20 EER26409.1 - 0.045 13.5 0.2 0.26 11.0 0.2 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.6 EER26409.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.6 EER26409.1 - 0.11 12.6 1.7 4.5 7.4 0.5 2.1 1 1 1 2 2 2 0 Thioredoxin SRP14 PF02290.15 EER26409.1 - 0.11 12.8 0.1 0.53 10.7 0.1 1.9 2 0 0 2 2 2 0 Signal recognition particle 14kD protein Thioredoxin_7 PF13899.6 EER26409.1 - 0.14 12.4 0.1 0.22 11.7 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like BAG PF02179.16 EER26411.1 - 6.9e-17 61.7 1.9 1.7e-16 60.4 1.9 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EER26411.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EER26411.1 - 0.022 15.3 0.1 0.053 14.1 0.1 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rrn6 PF10214.9 EER26411.1 - 0.51 8.8 7.9 0.71 8.3 7.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor LMBR1 PF04791.16 EER26412.1 - 1.1e-131 440.3 3.1 1.2e-131 440.1 3.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3675 PF12428.8 EER26412.1 - 9.5 6.8 8.0 1 9.9 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Med15_fungi PF05397.12 EER26414.1 - 5.9e-33 113.5 0.8 5.9e-33 113.5 0.8 2.8 2 0 0 2 2 2 1 Mediator complex subunit 15 Aft1_HRA PF11786.8 EER26415.1 - 3.2e-22 78.6 10.0 3.2e-22 78.6 10.0 2.7 3 1 1 4 4 4 1 Aft1 HRA domain Aft1_HRR PF11787.8 EER26415.1 - 4.5e-22 79.0 1.9 4.5e-22 79.0 1.9 3.3 2 1 0 2 2 2 1 Aft1 HRR domain Aft1_OSA PF11785.8 EER26415.1 - 6e-17 61.8 6.2 2.1e-16 60.1 6.2 2.0 1 0 0 1 1 1 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.21 EER26415.1 - 0.00011 22.2 2.0 0.00019 21.5 2.0 1.3 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 EER26415.1 - 0.24 11.2 0.8 0.4 10.5 0.8 1.3 1 0 0 1 1 1 0 Septum formation initiator FAM76 PF16046.5 EER26415.1 - 0.8 9.0 7.9 1.1 8.5 7.9 1.1 1 0 0 1 1 1 0 FAM76 protein Pap_E4 PF02711.14 EER26416.1 - 0.019 15.9 1.0 0.028 15.4 1.0 1.2 1 0 0 1 1 1 0 E4 protein Dscam_C PF12355.8 EER26416.1 - 0.38 11.7 3.6 0.59 11.1 3.6 1.3 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal CAP_N PF01213.19 EER26416.1 - 0.41 10.1 9.0 0.54 9.7 9.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EER26416.1 - 2.1 8.3 3.4 2.6 8.1 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 EER26416.1 - 2.8 8.0 8.7 5.1 7.2 8.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 ArsA_ATPase PF02374.15 EER26417.1 - 2e-111 372.1 0.0 2.2e-111 371.9 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EER26417.1 - 2.4e-14 53.7 0.2 8.2e-13 48.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EER26417.1 - 5.5e-13 49.1 0.0 1.3e-12 47.9 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EER26417.1 - 1.8e-06 27.6 0.1 4.7e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EER26417.1 - 3.4e-06 26.7 0.7 0.00011 21.7 0.1 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EER26417.1 - 2.2e-05 24.2 0.3 0.00078 19.1 0.1 2.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EER26417.1 - 6.7e-05 22.5 0.0 0.00027 20.5 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 EER26417.1 - 0.028 13.9 0.0 0.092 12.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 EER26417.1 - 0.056 13.0 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EER26417.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 EER26417.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EER26417.1 - 0.19 11.4 0.0 0.72 9.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain eIF3_N PF09440.10 EER26419.1 - 1.3e-50 171.3 4.3 1.9e-50 170.7 2.2 2.2 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EER26419.1 - 6.7e-15 55.5 0.0 4.7e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 PCI domain Img2 PF05046.14 EER26420.1 - 5.1e-25 87.6 0.0 7.6e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.21 EER26421.1 - 7.7e-18 65.0 0.0 1.7e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.29 EER26422.1 - 3e-45 153.9 0.6 8.1e-45 152.5 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EER26422.1 - 1.3e-10 41.0 0.1 7.6e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EER26422.1 - 6.5e-09 35.9 0.4 2.2e-08 34.2 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EER26422.1 - 4.6e-08 33.4 0.0 9.9e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EER26422.1 - 1.7e-07 31.8 0.3 3.8e-05 24.2 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EER26422.1 - 3.1e-06 26.5 0.0 5.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EER26422.1 - 3.9e-05 23.9 1.2 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EER26422.1 - 0.00024 20.9 0.0 0.00069 19.4 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EER26422.1 - 0.00027 20.5 0.0 0.0026 17.3 0.1 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 EER26422.1 - 0.00036 21.1 0.0 0.0015 19.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 EER26422.1 - 0.00038 20.2 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_28 PF13521.6 EER26422.1 - 0.00068 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EER26422.1 - 0.00092 19.3 0.1 0.0055 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EER26422.1 - 0.0013 18.7 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EER26422.1 - 0.0018 18.6 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EER26422.1 - 0.0025 17.1 0.0 0.0047 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain NTPase_1 PF03266.15 EER26422.1 - 0.0037 17.2 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 EER26422.1 - 0.0045 16.7 0.4 0.014 15.1 0.1 2.0 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EER26422.1 - 0.0055 16.6 0.2 0.11 12.3 0.0 2.7 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 EER26422.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EER26422.1 - 0.0072 16.1 0.1 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EER26422.1 - 0.008 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EER26422.1 - 0.0083 16.3 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EER26422.1 - 0.01 15.3 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 EER26422.1 - 0.024 14.4 0.2 0.054 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EER26422.1 - 0.037 13.9 1.2 0.33 10.8 0.0 2.6 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EER26422.1 - 0.041 13.2 1.0 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Bac_DnaA PF00308.18 EER26422.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_11 PF13086.6 EER26422.1 - 0.05 13.4 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EER26422.1 - 0.062 12.9 1.3 0.27 10.8 0.1 2.3 2 1 1 3 3 3 0 AAA domain AFG1_ATPase PF03969.16 EER26422.1 - 0.077 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 EER26422.1 - 0.078 12.7 0.2 1.3 8.7 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EER26422.1 - 0.091 12.0 0.1 0.22 10.8 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin Viral_Hsp90 PF03225.14 EER26422.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_19 PF13245.6 EER26422.1 - 0.12 12.7 0.1 0.38 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EER26422.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EER26422.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 EER26422.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.23 EER26423.1 - 7e-107 357.5 0.0 8.5e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EER26423.1 - 1.1e-15 58.3 0.4 1.8e-13 51.1 0.4 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EER26423.1 - 2.4e-05 24.9 0.1 0.16 12.7 0.0 3.5 3 2 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EER26423.1 - 0.0029 18.1 0.0 3.9 8.1 0.0 3.0 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EER26423.1 - 0.0039 17.0 0.0 0.024 14.4 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal NIF PF03031.18 EER26424.1 - 1.1e-26 93.4 0.0 2.4e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EER26424.1 - 2.3e-08 34.3 0.0 4.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EER26424.1 - 2.7e-06 27.7 0.1 5e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Biotin_lipoyl_2 PF13533.6 EER26424.1 - 3.1e-05 23.7 0.0 0.17 11.8 0.0 2.8 2 0 0 2 2 2 2 Biotin-lipoyl like PTCB-BRCT PF12738.7 EER26424.1 - 3.3e-05 23.7 0.1 8.4e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain RTT107_BRCT_5 PF16770.5 EER26424.1 - 0.01 15.7 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain MARVEL PF01284.23 EER26425.1 - 0.0042 17.1 19.8 0.0095 16.0 19.8 1.7 1 1 0 1 1 1 1 Membrane-associating domain Peptidase_S68 PF10461.9 EER26425.1 - 0.11 12.7 0.3 0.24 11.6 0.3 1.5 1 0 0 1 1 1 0 Peptidase S68 Arginase PF00491.21 EER26426.1 - 1.7e-72 244.3 0.3 1.9e-72 244.1 0.3 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.15 EER26427.1 - 2.6e-76 256.6 0.0 3.9e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EER26427.1 - 5.5e-22 78.2 0.0 9.4e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 GatB domain NPBW PF15180.6 EER26427.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Neuropeptides B and W Bromodomain PF00439.25 EER26429.1 - 0.018 15.1 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 Bromodomain GCOM2 PF15328.6 EER26429.1 - 1.7 9.0 7.2 9.3 6.6 1.2 2.6 2 0 0 2 2 2 0 Putative GRINL1B complex locus protein 2 ECH_1 PF00378.20 EER26431.1 - 6.1e-40 137.1 0.0 1.3e-39 136.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER26431.1 - 1.9e-26 93.4 0.0 2.3e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pox_P21 PF05313.12 EER26431.1 - 0.053 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein NB-ARC PF00931.22 EER26432.1 - 6e-10 38.7 0.0 2.4e-09 36.8 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain PGAP1 PF07819.13 EER26432.1 - 1.7e-05 24.7 0.0 3.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein AAA_16 PF13191.6 EER26432.1 - 4.2e-05 24.0 0.0 0.0001 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF676 PF05057.14 EER26432.1 - 0.00031 20.3 0.0 0.00055 19.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EER26432.1 - 0.031 14.9 0.0 0.031 14.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family AAA_22 PF13401.6 EER26432.1 - 0.043 14.1 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mst1_SARAH PF11629.8 EER26432.1 - 0.44 10.7 4.6 9.6 6.4 0.4 2.4 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 YtxH PF12732.7 EER26433.1 - 0.035 14.6 11.3 0.27 11.8 9.1 2.1 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.13 EER26433.1 - 0.07 13.7 6.9 0.063 13.9 5.0 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) FHA PF00498.26 EER26434.1 - 1e-12 48.2 0.0 2.2e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain DnaJ PF00226.31 EER26435.1 - 1.2e-07 31.8 0.2 2.3e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.13 EER26436.1 - 2.2e-40 138.8 0.1 1.2e-39 136.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EER26436.1 - 0.0065 15.4 0.0 0.016 14.0 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase BORCS6 PF10157.9 EER26437.1 - 0.077 13.2 0.9 0.18 12.0 0.9 1.5 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 6 Atg14 PF10186.9 EER26437.1 - 0.54 9.3 4.5 1 8.4 4.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zf-CpG_bind_C PF12269.8 EER26437.1 - 1.5 8.6 3.6 3.3 7.4 3.6 1.6 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Spt20 PF12090.8 EER26439.1 - 0.57 9.8 9.7 0.82 9.2 9.7 1.2 1 0 0 1 1 1 0 Spt20 family HMG_box PF00505.19 EER26440.1 - 1.5e-25 89.4 1.2 1.5e-25 89.4 1.2 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EER26440.1 - 8.7e-20 71.1 1.6 1.5e-19 70.3 1.6 1.4 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EER26440.1 - 0.0018 18.8 0.1 0.0018 18.8 0.1 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box_5 PF14887.6 EER26440.1 - 0.013 15.5 0.5 0.026 14.5 0.5 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CHDNT PF08073.12 EER26440.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Prp31_C PF09785.9 EER26440.1 - 0.42 11.5 5.6 0.51 11.3 5.6 1.1 1 0 0 1 1 1 0 Prp31 C terminal domain APH PF01636.23 EER26442.1 - 8e-10 39.0 0.5 3.4e-09 37.0 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER26442.1 - 0.0034 17.0 0.0 0.0051 16.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4135 PF13575.6 EER26442.1 - 0.034 13.5 0.0 0.044 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RIO1 PF01163.22 EER26442.1 - 0.099 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family CENP-H PF05837.12 EER26443.1 - 7e-24 84.4 3.5 7e-24 84.4 3.5 1.8 2 0 0 2 2 2 1 Centromere protein H (CENP-H) ATG11 PF10377.9 EER26444.1 - 6e-45 152.4 0.3 6e-45 152.4 0.3 4.1 3 1 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.12 EER26444.1 - 4.7e-05 22.7 9.0 0.00018 20.8 2.1 5.8 3 2 1 4 4 4 2 Autophagy protein Apg17 DUF4407 PF14362.6 EER26444.1 - 0.0042 16.5 15.0 0.0042 16.5 15.0 5.2 5 0 0 5 5 5 2 Domain of unknown function (DUF4407) DUF4078 PF13300.6 EER26445.1 - 3.5e-28 97.7 9.3 3.5e-28 97.7 9.3 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) RAP1 PF07218.11 EER26445.1 - 0.74 8.0 3.0 0.36 9.0 0.8 1.3 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Homoserine_dh PF00742.19 EER26446.1 - 1e-52 178.6 0.0 1.3e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EER26446.1 - 4.2e-14 53.2 0.0 1.1e-13 51.8 0.0 1.8 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3445 PF11927.8 EER26447.1 - 3.2e-79 265.7 0.0 4.1e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Phage_head_chap PF11113.8 EER26448.1 - 0.018 15.1 0.0 0.11 12.6 0.0 2.2 3 0 0 3 3 3 0 Head assembly gene product DUF3294 PF07957.11 EER26448.1 - 0.061 13.1 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) HAD_2 PF13419.6 EER26448.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase RSN1_7TM PF02714.15 EER26450.1 - 6.8e-78 261.7 21.5 1.2e-77 261.0 21.5 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EER26450.1 - 4.7e-43 147.4 0.0 7e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EER26450.1 - 2.4e-42 144.4 0.1 2.4e-42 144.4 0.1 2.5 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF1192 PF06698.11 EER26450.1 - 0.11 12.6 0.2 0.32 11.1 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) HNH_2 PF13391.6 EER26451.1 - 1.4e-13 50.7 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease F_bP_aldolase PF01116.20 EER26452.1 - 5.4e-92 308.2 0.0 6.1e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.29 EER26453.1 - 3e-37 128.5 0.0 3.1e-32 112.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER26453.1 - 1.9e-07 31.0 0.9 0.0049 16.5 1.1 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase CUE PF02845.16 EER26456.1 - 1.4e-11 43.9 0.0 2.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain peroxidase PF00141.23 EER26456.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Peroxidase RTA1 PF04479.13 EER26457.1 - 1.8e-54 184.5 8.3 2.1e-54 184.3 8.3 1.0 1 0 0 1 1 1 1 RTA1 like protein Oxysterol_BP PF01237.18 EER26458.1 - 4.7e-63 213.3 1.7 6.9e-61 206.1 1.7 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Sugar_tr PF00083.24 EER26459.1 - 6.8e-81 272.4 11.3 8.7e-81 272.1 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER26459.1 - 7e-14 51.5 24.9 1.4e-13 50.5 24.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily LegC3_N PF18654.1 EER26460.1 - 0.015 14.5 0.9 1.7 7.8 0.8 2.2 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain PUD PF03714.14 EER26461.1 - 0.11 13.3 1.1 10 7.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial pullanase-associated domain RNase_T PF00929.24 EER26462.1 - 1.5e-25 90.7 0.0 1.7e-25 90.5 0.0 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.16 EER26463.1 - 4.2e-34 117.2 0.2 6.4e-34 116.6 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EER26463.1 - 2.5e-27 95.3 0.0 4.5e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EER26463.1 - 4.4e-17 62.6 0.0 1.2e-16 61.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EER26463.1 - 6.1e-09 35.9 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 EER26464.1 - 2.7e-11 44.4 0.0 7.7e-11 42.9 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EER26464.1 - 0.00039 20.4 0.0 0.00084 19.3 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Acetyltransf_10 PF13673.7 EER26466.1 - 1.2e-09 38.2 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER26466.1 - 5e-08 33.3 0.0 9.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER26466.1 - 5.3e-08 33.1 0.0 1.1e-07 32.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EER26466.1 - 1.3e-06 28.5 0.0 3.2e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER26466.1 - 0.00035 20.7 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EER26466.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein HMG_CoA_synt_C PF08540.10 EER26467.1 - 1.9e-105 352.5 0.1 2.4e-105 352.2 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EER26467.1 - 4.4e-97 323.0 0.1 7.1e-97 322.3 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Pkinase PF00069.25 EER26468.1 - 4.1e-24 85.4 0.0 5.6e-23 81.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26468.1 - 5.8e-07 29.0 0.0 0.00088 18.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER26468.1 - 0.0043 15.9 0.0 0.006 15.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Nnf1 PF03980.14 EER26469.1 - 1.1e-31 109.5 0.4 1.1e-31 109.5 0.4 1.6 2 0 0 2 2 2 1 Nnf1 DMPK_coil PF08826.10 EER26469.1 - 0.022 14.8 0.3 0.022 14.8 0.3 1.9 2 0 0 2 2 2 0 DMPK coiled coil domain like DUF16 PF01519.16 EER26469.1 - 0.023 15.2 0.0 0.15 12.5 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DEC-1_N PF04625.13 EER26469.1 - 0.75 8.7 4.6 0.26 10.2 1.8 1.7 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Phage_portal_2 PF05136.13 EER26470.1 - 0.071 12.3 0.0 0.083 12.0 0.0 1.1 1 0 0 1 1 1 0 Phage portal protein, lambda family APH PF01636.23 EER26471.1 - 1.3e-12 48.1 0.1 3.5e-12 46.8 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EER26471.1 - 0.041 13.5 0.0 9.1 5.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family KcnmB2_inactiv PF09303.10 EER26471.1 - 0.062 13.1 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 KCNMB2, ball and chain domain APH PF01636.23 EER26472.1 - 5e-18 65.9 0.0 8.4e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EER26472.1 - 7.5e-06 25.4 0.0 0.1 11.9 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EER26472.1 - 0.00028 20.5 0.0 0.00053 19.6 0.0 1.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 EER26472.1 - 0.021 14.4 0.1 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family TFR_dimer PF04253.15 EER26473.1 - 2.6e-36 124.4 0.1 4.6e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EER26473.1 - 1.6e-21 76.9 0.0 8.1e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.22 EER26473.1 - 9.3e-14 51.2 0.1 2.2e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 PA domain TFIIB PF00382.19 EER26474.1 - 7.8e-38 128.4 0.1 3.4e-19 68.7 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EER26474.1 - 8.1e-12 44.5 0.6 8.1e-12 44.5 0.6 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding RB_B PF01857.20 EER26474.1 - 0.00055 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain Cyclin_C PF02984.19 EER26474.1 - 0.019 15.0 0.0 3.2 7.9 0.0 2.7 3 0 0 3 3 3 0 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.6 EER26474.1 - 0.022 14.2 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Cyclin_N PF00134.23 EER26474.1 - 0.034 13.9 0.1 0.67 9.7 0.0 2.1 2 0 0 2 2 2 0 Cyclin, N-terminal domain Zn_ribbon_SprT PF17283.2 EER26474.1 - 0.081 12.8 0.8 1.1 9.2 0.1 2.3 2 0 0 2 2 2 0 SprT-like zinc ribbon domain DUF1610 PF07754.11 EER26474.1 - 0.25 11.4 2.4 1.2 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Auto_anti-p27 PF06677.12 EER26474.1 - 7.9 6.7 6.0 2.3 8.4 1.8 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ATP_sub_h PF10775.9 EER26475.1 - 4.7e-25 87.4 3.4 4.7e-25 87.4 3.4 1.5 2 0 0 2 2 2 1 ATP synthase complex subunit h 4HBT_3 PF13622.6 EER26475.1 - 0.0027 18.0 1.4 0.0031 17.8 1.4 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily ATP-synt_F6 PF05511.11 EER26475.1 - 0.013 15.9 0.0 0.017 15.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 DUF1765 PF08578.10 EER26476.1 - 1.7e-44 151.3 0.9 4e-44 150.1 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Serglycin PF04360.12 EER26476.1 - 0.0069 16.3 0.3 0.048 13.6 0.1 2.4 2 0 0 2 2 2 1 Serglycin Aim21 PF11489.8 EER26477.1 - 4.3e-189 630.9 82.2 4.3e-189 630.9 82.2 2.2 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 Cg6151-P PF10233.9 EER26478.1 - 1.4e-34 118.8 11.7 1.6e-34 118.6 11.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Cytochrom_B558a PF05038.13 EER26478.1 - 0.073 12.6 1.1 0.95 9.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit DHHC PF01529.20 EER26478.1 - 2.8 8.0 5.0 5.7 7.0 4.8 1.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase ATP1G1_PLM_MAT8 PF02038.16 EER26478.1 - 3 7.3 4.9 11 5.5 0.1 2.4 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family PfkB PF00294.24 EER26479.1 - 4.9e-21 75.3 0.0 2.3e-20 73.1 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase NTF2 PF02136.20 EER26480.1 - 2.6e-33 115.2 0.0 2.9e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.20 EER26481.1 - 1.1e-08 35.0 0.0 2.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Surp module DUF2264 PF10022.9 EER26481.1 - 0.056 12.5 0.1 0.097 11.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Rick_17kDa_Anti PF05433.15 EER26483.1 - 0.0015 18.4 0.6 0.0026 17.6 0.6 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EER26483.1 - 0.11 12.5 1.2 0.21 11.6 1.2 1.3 1 0 0 1 1 1 0 Glycine zipper Ish1 PF10281.9 EER26484.1 - 9e-75 246.7 26.3 1.1e-13 51.2 0.0 8.0 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EER26484.1 - 5.9e-08 32.3 0.0 0.1 12.4 0.0 5.1 5 0 0 5 5 5 1 SAP domain HeH PF12949.7 EER26484.1 - 2e-06 27.4 0.5 5.2 6.9 0.0 5.3 6 0 0 6 6 6 2 HeH/LEM domain Tir_receptor_M PF03549.14 EER26484.1 - 0.0025 18.1 0.0 11 6.4 0.0 3.7 2 1 1 3 3 3 1 Translocated intimin receptor (Tir) intimin-binding domain Slx4 PF09494.10 EER26484.1 - 0.0035 17.3 0.1 1.1e+02 2.9 0.0 4.8 5 0 0 5 5 5 0 Slx4 endonuclease DUF4230 PF14014.6 EER26484.1 - 0.017 15.4 4.3 1.5 9.1 0.1 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF4230) TetR_C_11 PF16859.5 EER26484.1 - 0.03 14.6 1.2 10 6.4 0.1 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Arena_ncap_C PF17290.2 EER26484.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain SAP30_Sin3_bdg PF13867.6 EER26484.1 - 0.11 12.9 2.0 42 4.6 0.0 4.3 5 0 0 5 5 5 0 Sin3 binding region of histone deacetylase complex subunit SAP30 GP52 PF17468.2 EER26484.1 - 0.14 12.3 2.9 6.2 7.1 0.0 4.0 4 0 0 4 4 4 0 Phage gene product 52 Recombinase PF07508.13 EER26484.1 - 0.32 11.4 4.7 4.5 7.7 0.0 3.8 3 1 1 4 4 4 0 Recombinase SAM_2 PF07647.17 EER26484.1 - 0.62 10.2 2.7 58 3.9 0.0 4.9 6 0 0 6 6 6 0 SAM domain (Sterile alpha motif) PQ-loop PF04193.14 EER26485.1 - 7.4e-19 67.3 19.1 3.9e-11 42.5 2.9 3.4 3 1 1 4 4 4 2 PQ loop repeat DUF1345 PF07077.11 EER26485.1 - 0.0042 16.8 3.5 0.0051 16.5 2.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1345) DUF1240 PF06836.12 EER26485.1 - 6.1 7.4 6.6 0.42 11.2 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Glyco_transf_90 PF05686.12 EER26487.1 - 3.9e-14 52.4 1.1 1.1e-11 44.3 0.8 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF5336 PF17270.2 EER26487.1 - 0.0097 15.5 3.1 0.0097 15.5 3.1 2.0 2 1 0 2 2 2 1 Family of unknown function (DUF5336) HlyIII PF03006.20 EER26487.1 - 1.3 8.7 6.6 0.58 9.8 1.2 2.7 2 1 1 3 3 3 0 Haemolysin-III related Cyt-b5 PF00173.28 EER26488.1 - 2.4e-15 56.4 0.0 3.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fib_alpha PF08702.10 EER26489.1 - 0.6 10.3 1.9 3.9 7.6 1.6 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family TMA7 PF09072.10 EER26490.1 - 9.2e-25 87.3 18.1 1.1e-24 87.0 18.1 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 EER26491.1 - 2.6e-53 181.1 0.0 4.4e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26491.1 - 9.2e-24 84.1 0.0 3.6e-23 82.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EER26491.1 - 0.00098 19.1 0.2 2.1 8.2 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EER26491.1 - 0.046 12.7 0.0 0.072 12.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 EER26492.1 - 2.5e-53 181.1 0.0 3.4e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26492.1 - 1.2e-33 116.5 0.0 1.5e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER26492.1 - 0.0031 17.5 0.0 0.023 14.6 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EER26492.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 EER26492.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 EER26493.1 - 9.9e-48 162.2 3.2 1.3e-47 161.9 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER26493.1 - 7.3e-47 159.9 3.1 1.6e-39 135.8 3.0 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER26493.1 - 2.3e-14 53.7 0.7 3.4e-14 53.2 0.7 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EER26493.1 - 0.0027 18.0 0.1 0.0042 17.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EER26493.1 - 0.0048 16.8 0.9 0.011 15.6 0.9 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EER26493.1 - 0.0091 16.3 0.2 0.019 15.2 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.15 EER26493.1 - 0.032 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EER26493.1 - 0.037 13.4 0.0 0.05 13.0 0.0 1.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase 2-Hacid_dh_C PF02826.19 EER26493.1 - 0.095 12.0 0.1 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HlyIII PF03006.20 EER26494.1 - 1.6e-64 217.7 19.2 1.9e-64 217.4 19.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related 60KD_IMP PF02096.20 EER26494.1 - 0.1 12.5 0.1 0.25 11.2 0.1 1.7 1 1 0 1 1 1 0 60Kd inner membrane protein YbaB_DNA_bd PF02575.16 EER26494.1 - 0.23 11.7 0.5 0.34 11.2 0.5 1.2 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family DUF308 PF03729.13 EER26494.1 - 0.74 10.2 16.5 0.076 13.4 6.3 3.1 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) TPR_19 PF14559.6 EER26496.1 - 3.4e-05 24.3 0.0 0.27 11.8 0.1 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.14 EER26496.1 - 0.17 12.6 1.0 67 4.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 EER26497.1 - 6e-33 114.1 0.0 7.5e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EER26497.1 - 2.2e-12 47.4 0.0 2.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EER26497.1 - 0.00049 19.7 0.0 0.00067 19.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EER26497.1 - 0.0032 17.0 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1749 PF08538.10 EER26498.1 - 5.3e-98 327.8 0.0 6e-98 327.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 EER26498.1 - 0.16 11.2 0.0 0.44 9.8 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MSP1a PF11670.8 EER26500.1 - 0.21 10.9 2.3 0.34 10.2 2.3 1.3 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Vps35 PF03635.17 EER26501.1 - 0 1031.3 3.7 0 1031.2 3.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RIH_assoc PF08454.11 EER26501.1 - 0.11 12.3 4.3 4.6 7.2 0.3 3.3 3 0 0 3 3 3 0 RyR and IP3R Homology associated Xpo1 PF08389.12 EER26501.1 - 0.44 10.6 3.4 9.7 6.2 0.0 3.8 4 0 0 4 4 4 0 Exportin 1-like protein NST1 PF13945.6 EER26502.1 - 3.2e-77 259.0 7.3 3.2e-77 259.0 7.3 5.6 4 2 1 5 5 5 1 Salt tolerance down-regulator Ras PF00071.22 EER26503.1 - 5.3e-50 169.2 0.0 6.2e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER26503.1 - 6.2e-23 81.3 0.0 9.3e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER26503.1 - 1.3e-06 28.0 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EER26503.1 - 0.006 16.0 0.0 0.0065 15.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EER26503.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EER26503.1 - 0.066 13.0 0.0 2.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EER26503.1 - 0.081 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EER26503.1 - 0.18 11.6 0.1 0.43 10.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MRP-L28 PF09812.9 EER26504.1 - 2.9e-06 27.5 0.0 4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.7 EER26505.1 - 4.8e-06 26.6 6.1 1e-05 25.6 6.1 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EER26505.1 - 5.7e-05 23.2 3.0 0.00011 22.3 3.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EER26505.1 - 0.14 12.5 5.3 0.28 11.5 5.3 1.6 1 0 0 1 1 1 0 Ring finger domain TPP_enzyme_N PF02776.18 EER26506.1 - 6.8e-55 185.3 0.0 8.6e-54 181.7 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EER26506.1 - 2.1e-50 170.5 0.5 9.1e-48 161.9 0.0 3.3 3 1 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EER26506.1 - 2.1e-38 131.2 0.2 5e-38 129.9 0.2 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EER26506.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GalKase_gal_bdg PF10509.9 EER26507.1 - 2.2e-18 65.5 0.0 4e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EER26507.1 - 3.1e-14 52.9 1.8 7.4e-14 51.7 1.4 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EER26507.1 - 3.6e-14 52.9 0.0 8.3e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.12 EER26507.1 - 0.06 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 RNase_H2-Ydr279 PF09468.10 EER26508.1 - 7.5e-40 136.7 0.8 7.5e-40 136.7 0.8 2.1 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EER26508.1 - 5.4e-20 71.4 0.3 2.9e-19 69.1 0.0 2.4 3 0 0 3 3 3 1 Ydr279p protein triple barrel domain RNA_pol_Rpc4 PF05132.14 EER26508.1 - 5.4 7.4 8.6 14 6.1 1.6 2.9 3 0 0 3 3 3 0 RNA polymerase III RPC4 zf-primase PF09329.11 EER26509.1 - 5.4e-18 64.5 1.3 9e-18 63.8 1.3 1.4 1 0 0 1 1 1 1 Primase zinc finger DASH_Duo1 PF08651.10 EER26511.1 - 3.8e-31 106.7 0.7 7.8e-31 105.7 0.7 1.5 1 0 0 1 1 1 1 DASH complex subunit Duo1 Macoilin PF09726.9 EER26511.1 - 0.0089 14.6 5.4 0.011 14.4 5.4 1.2 1 0 0 1 1 1 1 Macoilin family DUF2514 PF10721.9 EER26511.1 - 0.09 12.8 14.8 0.16 12.0 14.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF1682 PF07946.14 EER26511.1 - 0.1 11.8 4.1 0.12 11.5 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FCH PF00611.23 EER26513.1 - 4e-16 59.1 0.2 1.4e-15 57.3 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EER26513.1 - 2.3e-12 46.3 0.0 4.4e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EER26513.1 - 2.6e-10 39.8 0.0 1.9e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EER26513.1 - 3.2e-09 36.5 0.0 6.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF5425 PF17472.2 EER26513.1 - 0.11 13.3 0.4 0.42 11.4 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5425) Spore_III_AF PF09581.10 EER26513.1 - 0.47 10.4 2.5 1.2 9.2 0.0 3.0 3 1 0 4 4 4 0 Stage III sporulation protein AF (Spore_III_AF) Zip PF02535.22 EER26513.1 - 5.1 6.2 6.9 14 4.7 6.9 1.9 1 0 0 1 1 1 0 ZIP Zinc transporter Not1 PF04054.15 EER26514.1 - 9.2e-140 465.7 1.1 5.8e-139 463.1 0.0 2.7 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EER26514.1 - 8.8e-94 313.1 0.7 2.2e-93 311.8 0.7 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EER26514.1 - 8.8e-51 171.7 3.3 2.3e-50 170.3 3.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EER26514.1 - 2.6e-41 140.9 0.0 7.5e-41 139.4 0.0 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EER26514.1 - 3.4e-29 101.9 0.0 1e-28 100.3 0.0 1.9 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Phage_GP20 PF06810.11 EER26514.1 - 0.12 12.2 0.1 0.43 10.4 0.1 1.9 1 0 0 1 1 1 0 Phage minor structural protein GP20 Seipin PF06775.14 EER26515.1 - 5e-59 199.7 1.5 6.7e-59 199.3 1.5 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.15 EER26516.1 - 2.2e-56 191.2 0.0 3.2e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EER26516.1 - 4.8e-47 160.3 0.0 7e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EER26516.1 - 3.3e-05 23.3 0.0 0.00036 19.9 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_2 PF13477.6 EER26516.1 - 0.13 12.3 0.1 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like Dala_Dala_lig_C PF07478.13 EER26516.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ADH_N PF08240.12 EER26517.1 - 6.6e-24 83.9 2.7 1.1e-23 83.1 2.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER26517.1 - 1.2e-14 54.4 0.0 1.8e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EER26517.1 - 0.00017 21.0 0.0 0.00027 20.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EER26517.1 - 0.0019 18.0 0.0 0.0069 16.1 0.0 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ADH_zinc_N_2 PF13602.6 EER26517.1 - 0.011 16.8 0.0 0.047 14.7 0.0 2.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EER26517.1 - 0.024 13.9 0.1 0.056 12.7 0.1 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Haem_degrading PF03928.14 EER26517.1 - 0.18 11.9 0.8 0.42 10.7 0.8 1.6 1 0 0 1 1 1 0 Haem-degrading ABC_tran PF00005.27 EER26518.1 - 1.1e-32 113.4 0.0 4.5e-32 111.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EER26518.1 - 2.3e-23 83.2 3.6 2.3e-23 83.2 3.6 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 EER26518.1 - 1.4e-05 24.6 0.2 0.0043 16.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EER26518.1 - 0.0022 18.5 0.1 0.0054 17.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EER26518.1 - 0.021 14.6 0.2 0.068 12.9 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EER26518.1 - 0.034 14.2 0.2 0.066 13.3 0.2 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_22 PF13401.6 EER26518.1 - 0.094 13.0 0.1 0.25 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EER26518.1 - 0.11 12.2 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EER26518.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 EER26518.1 - 0.19 11.5 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system PAM2 PF07145.15 EER26518.1 - 0.34 10.7 1.0 0.75 9.6 1.0 1.6 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Pex14_N PF04695.13 EER26520.1 - 1.5e-42 145.9 0.0 1.5e-42 145.9 0.0 3.0 2 1 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.8 EER26520.1 - 0.00036 18.2 2.2 0.00044 17.9 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 EER26520.1 - 0.0078 15.7 1.8 0.012 15.1 1.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF1043 PF06295.12 EER26520.1 - 0.05 13.6 0.2 0.11 12.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Baculo_PEP_C PF04513.12 EER26520.1 - 0.11 12.6 0.6 3 7.9 0.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.6 EER26520.1 - 0.13 11.9 3.6 0.21 11.2 3.6 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Prominin PF05478.11 EER26520.1 - 0.14 10.0 0.0 0.19 9.6 0.0 1.1 1 0 0 1 1 1 0 Prominin DASH_Spc19 PF08287.11 EER26520.1 - 0.15 12.0 6.0 0.31 10.9 6.0 1.5 1 0 0 1 1 1 0 Spc19 SYCE1 PF15233.6 EER26520.1 - 0.48 10.5 3.1 0.83 9.7 3.1 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 FlgN PF05130.12 EER26520.1 - 0.64 10.5 4.8 1.4 9.4 4.8 1.5 1 0 0 1 1 1 0 FlgN protein zf-C4H2 PF10146.9 EER26520.1 - 0.83 9.9 7.5 0.078 13.3 2.5 2.0 2 1 0 2 2 2 0 Zinc finger-containing protein DUF1664 PF07889.12 EER26520.1 - 1.2 9.2 3.8 4.7 7.3 3.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ERM PF00769.19 EER26520.1 - 4.2 7.1 9.9 0.84 9.4 4.5 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family ZapB PF06005.12 EER26520.1 - 7.5 7.1 6.1 8.3 6.9 0.2 2.6 3 0 0 3 3 3 0 Cell division protein ZapB Ndc80_HEC PF03801.13 EER26521.1 - 1.5e-61 206.5 0.4 3.4e-61 205.4 0.4 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Cep57_CLD PF14073.6 EER26521.1 - 0.27 11.3 37.1 0.065 13.3 19.3 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Spc7 PF08317.11 EER26521.1 - 0.34 9.7 40.3 0.14 11.0 10.3 3.2 2 1 0 2 2 2 0 Spc7 kinetochore protein ComP_DUS PF16732.5 EER26521.1 - 3.9 8.4 5.5 3.3 8.7 0.1 3.1 3 0 0 3 3 3 0 Type IV minor pilin ComP, DNA uptake sequence receptor Pkinase PF00069.25 EER26523.1 - 1.5e-64 217.9 0.0 1.9e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26523.1 - 4.1e-28 98.4 0.0 6.3e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER26523.1 - 0.032 13.0 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EER26523.1 - 0.047 13.3 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EER26523.1 - 0.065 12.2 0.1 0.092 11.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EER26523.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.5 1 1 0 1 1 1 0 Kinase-like FolB PF02152.18 EER26524.1 - 4.4e-28 98.0 0.1 1.8e-23 83.2 0.4 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase SNX17_FERM_C PF18116.1 EER26524.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Sorting Nexin 17 FERM C-terminal domain RRM_1 PF00076.22 EER26525.1 - 1e-21 76.5 0.0 6.1e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER26525.1 - 0.005 16.7 0.0 0.52 10.2 0.0 2.2 2 0 0 2 2 2 2 Occluded RNA-recognition motif ETF_QO PF05187.13 EER26526.1 - 7.7e-48 160.9 0.6 1.2e-47 160.3 0.6 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EER26526.1 - 1.7e-09 37.7 0.1 0.00068 19.3 0.4 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER26526.1 - 2.8e-06 27.5 0.0 6.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EER26526.1 - 3.6e-06 26.3 0.2 0.0051 16.0 0.8 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 EER26526.1 - 4.8e-05 22.7 0.0 0.0044 16.3 0.1 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EER26526.1 - 9.6e-05 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER26526.1 - 0.00029 19.7 0.5 0.00047 19.0 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 EER26526.1 - 0.00078 18.8 0.8 0.0012 18.2 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER26526.1 - 0.00079 19.9 0.0 1.6 9.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EER26526.1 - 0.0012 18.3 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EER26526.1 - 0.0018 17.6 0.1 0.0037 16.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EER26526.1 - 0.0034 16.3 0.0 0.1 11.4 0.2 2.1 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.6 EER26526.1 - 0.0069 16.4 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.7 EER26526.1 - 0.044 14.4 0.6 0.13 12.9 0.6 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Amino_oxidase PF01593.24 EER26526.1 - 0.048 12.9 0.0 0.092 12.0 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EER26526.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_2 PF12797.7 EER26526.1 - 0.12 12.6 0.6 0.3 11.3 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 EER26526.1 - 0.12 11.4 0.5 0.19 10.8 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Nitrate_red_gam PF02665.14 EER26526.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Lycopene_cycl PF05834.12 EER26526.1 - 0.22 10.5 0.3 0.32 10.0 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein TBP PF00352.21 EER26527.1 - 1.7e-67 223.4 0.1 9e-33 112.1 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EER26527.1 - 5.2e-05 23.3 0.0 0.22 11.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EER26527.1 - 0.12 12.2 0.1 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 EER26528.1 - 4.3e-48 164.7 0.5 4.9e-48 164.5 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER26528.1 - 6.3e-08 32.2 0.1 1.2e-05 24.7 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER26528.1 - 6e-05 23.2 0.0 0.00077 19.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EER26528.1 - 8.8e-05 22.5 1.4 0.11 12.5 0.3 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding GIDA PF01134.22 EER26528.1 - 0.00072 18.8 0.0 0.016 14.3 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EER26528.1 - 0.001 18.0 0.1 0.0099 14.8 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.27 EER26528.1 - 0.0011 19.5 0.0 0.0046 17.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EER26528.1 - 0.0026 16.9 0.0 0.34 9.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 EER26528.1 - 0.028 13.7 0.0 0.56 9.4 0.1 2.6 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 EER26528.1 - 0.057 12.5 0.1 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein GMC_oxred_N PF00732.19 EER26528.1 - 0.063 12.6 0.0 0.57 9.5 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase TrkA_N PF02254.18 EER26528.1 - 0.1 12.9 0.0 0.39 11.0 0.0 2.0 3 0 0 3 3 3 0 TrkA-N domain PEP-CTERM PF07589.11 EER26528.1 - 0.16 12.1 1.3 0.5 10.5 1.3 1.9 1 0 0 1 1 1 0 PEP-CTERM motif Methyltransf_23 PF13489.6 EER26529.1 - 6.9e-33 113.8 0.0 1e-32 113.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER26529.1 - 1.8e-06 28.5 0.0 8.5e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER26529.1 - 8.8e-06 26.4 0.0 1.6e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER26529.1 - 2.3e-05 24.2 0.0 4.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER26529.1 - 0.00033 21.2 0.0 0.0018 18.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain RskA PF10099.9 EER26529.1 - 0.066 13.5 2.0 0.11 12.7 2.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Cyclin_N PF00134.23 EER26531.1 - 2.9e-14 52.9 2.0 3.2e-14 52.7 0.1 2.0 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EER26531.1 - 2.5e-05 24.3 0.1 0.0012 19.0 0.0 2.4 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.19 EER26531.1 - 0.0025 17.8 1.7 0.56 10.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_C_2 PF16899.5 EER26531.1 - 0.061 13.7 0.1 0.21 12.0 0.0 2.0 2 0 0 2 2 2 0 Cyclin C-terminal domain EAF PF09816.9 EER26532.1 - 9.9e-19 67.6 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Dor1 PF04124.12 EER26533.1 - 3.2e-52 177.3 8.2 3.1e-46 157.6 5.6 2.9 1 1 1 2 2 2 2 Dor1-like family Vps51 PF08700.11 EER26533.1 - 3.4e-05 23.8 1.4 3.4e-05 23.8 1.4 2.2 2 0 0 2 2 2 1 Vps51/Vps67 SLX9 PF15341.6 EER26533.1 - 0.0064 16.9 4.4 1.2 9.6 0.1 3.5 2 1 1 3 3 3 2 Ribosome biogenesis protein SLX9 His_Phos_1 PF00300.22 EER26534.1 - 4.5e-16 59.1 0.0 8.8e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) P5-ATPase PF12409.8 EER26534.1 - 0.025 14.7 0.4 0.052 13.6 0.1 1.7 1 1 1 2 2 2 0 P5-type ATPase cation transporter Cyclin PF08613.11 EER26535.1 - 3.8e-10 40.4 0.0 4.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EER26535.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF2380 PF09533.10 EER26535.1 - 0.14 11.8 0.8 0.34 10.5 0.8 1.6 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) CRC_subunit PF08624.10 EER26536.1 - 3.9e-52 176.3 0.0 6.2e-52 175.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF5050 PF16472.5 EER26536.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5050) DUF4246 PF14033.6 EER26537.1 - 5.1e-185 615.9 0.1 6e-185 615.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 EER26537.1 - 0.0038 17.6 0.0 0.012 16.0 0.0 1.9 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Acyltransferase PF01553.21 EER26538.1 - 8.4e-08 31.9 0.0 1.8e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 EER26539.1 - 3.2e-69 233.2 0.0 4.9e-69 232.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26539.1 - 2.3e-31 109.0 0.0 3.3e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EER26539.1 - 4.7e-12 46.4 0.9 2.1e-11 44.3 0.3 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EER26539.1 - 7.3e-09 35.9 0.0 4.9e-07 30.0 0.1 2.5 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 EER26539.1 - 1.3e-08 34.5 0.0 6.8e-08 32.2 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EER26539.1 - 0.00042 19.4 0.3 0.0016 17.4 0.3 1.9 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EER26539.1 - 0.0071 16.0 0.3 2.6 7.6 0.1 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EER26539.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER26539.1 - 0.052 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EER26539.1 - 0.16 11.3 0.1 0.36 10.1 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 EER26540.1 - 0.0062 16.4 0.3 0.018 14.9 0.3 1.9 1 0 0 1 1 1 1 F-box-like AAA PF00004.29 EER26541.1 - 8.8e-40 136.2 0.0 2e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EER26541.1 - 7.4e-19 67.5 0.5 1.6e-18 66.4 0.5 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EER26541.1 - 3.2e-10 39.7 0.0 7.8e-10 38.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EER26541.1 - 9.6e-05 22.8 1.7 0.016 15.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EER26541.1 - 0.00011 22.2 1.0 0.00071 19.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EER26541.1 - 0.00038 20.3 0.0 0.00094 19.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EER26541.1 - 0.00093 19.4 0.1 0.011 15.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EER26541.1 - 0.0012 19.1 1.6 0.082 13.2 0.0 3.1 2 1 0 3 3 3 1 AAA domain DUF815 PF05673.13 EER26541.1 - 0.0013 17.9 1.7 0.047 12.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.16 EER26541.1 - 0.0052 16.3 0.3 0.085 12.3 0.2 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EER26541.1 - 0.0083 15.5 0.1 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EER26541.1 - 0.01 16.0 0.0 0.034 14.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EER26541.1 - 0.072 12.8 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EER26541.1 - 0.096 12.2 0.0 0.31 10.5 0.0 1.9 1 1 0 1 1 1 0 P-loop containing dynein motor region CLZ PF16526.5 EER26541.1 - 0.17 12.2 11.4 0.043 14.2 6.9 2.4 2 0 0 2 2 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_11 PF13086.6 EER26541.1 - 0.6 9.8 0.0 0.6 9.8 0.0 3.0 2 1 0 3 3 2 0 AAA domain TauD PF02668.16 EER26542.1 - 4e-37 128.5 0.1 7.4e-37 127.6 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EER26542.1 - 1.5e-14 54.4 0.1 4e-14 53.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.10 EER26542.1 - 0.029 13.5 0.0 0.11 11.6 0.0 1.8 1 1 0 1 1 1 0 CsiD MaoC_dehydratas PF01575.19 EER26543.1 - 6.7e-26 90.3 0.0 1.3e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EER26543.1 - 4.2e-11 43.1 0.0 3e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Methyltransf_25 PF13649.6 EER26544.1 - 1.7e-11 44.7 0.0 4.6e-11 43.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 EER26544.1 - 9.5e-11 41.6 0.0 1.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EER26544.1 - 5.1e-10 39.3 0.0 1.1e-09 38.2 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER26544.1 - 9.5e-08 32.6 0.0 3.4e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EER26544.1 - 8e-07 28.3 0.1 1.2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EER26544.1 - 1.1e-06 28.6 0.0 4.4e-06 26.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EER26544.1 - 1.5e-05 24.9 0.3 5.3e-05 23.2 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EER26544.1 - 0.00017 21.0 0.0 0.00026 20.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EER26544.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EER26544.1 - 0.00064 20.4 0.0 0.0014 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EER26544.1 - 0.0079 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PRMT5 PF05185.16 EER26544.1 - 0.0097 15.8 0.3 0.022 14.6 0.0 1.7 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 EER26544.1 - 0.011 15.5 0.2 0.021 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EER26544.1 - 0.017 14.5 0.1 0.036 13.4 0.1 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EER26544.1 - 0.018 15.0 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EER26544.1 - 0.082 12.3 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 EER26544.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_24 PF13578.6 EER26544.1 - 0.15 13.1 0.0 0.39 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Per1 PF04080.13 EER26545.1 - 1.8e-105 352.3 10.7 2.1e-105 352.1 10.7 1.0 1 0 0 1 1 1 1 Per1-like family PGM_PMM_I PF02878.16 EER26546.1 - 7.7e-16 58.0 0.4 1e-06 28.5 0.0 3.3 3 1 1 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EER26546.1 - 3.3e-12 46.4 0.7 8.5e-12 45.1 0.7 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EER26546.1 - 0.00092 19.4 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EER26546.1 - 0.0079 16.8 0.6 0.093 13.4 0.2 2.9 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II CinA_KH PF18146.1 EER26546.1 - 0.16 12.2 0.3 0.65 10.2 0.3 2.0 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain DEAD PF00270.29 EER26547.1 - 2.1e-47 161.2 0.0 3.2e-47 160.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26547.1 - 2.1e-29 102.1 0.0 7.8e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER26547.1 - 1.6e-05 25.0 0.0 3.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.18 EER26548.1 - 7.1e-50 169.8 1.5 9.6e-50 169.4 1.5 1.2 1 0 0 1 1 1 1 Brix domain Lum_binding PF00677.17 EER26550.1 - 3.1e-44 148.9 2.0 1.5e-21 76.2 0.6 2.2 2 0 0 2 2 2 2 Lumazine binding domain DUF2967 PF11179.8 EER26550.1 - 0.12 10.4 0.3 0.15 10.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) PHB_acc PF05233.13 EER26550.1 - 0.21 11.6 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 PHB accumulation regulatory domain CoA_transf_3 PF02515.17 EER26551.1 - 1.2e-129 432.7 0.0 1.3e-129 432.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.29 EER26552.1 - 3e-09 36.6 7.4 5.1e-09 35.9 7.4 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EER26552.1 - 0.12 12.4 4.7 0.22 11.5 4.7 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 FYVE_2 PF02318.16 EER26552.1 - 0.22 11.8 1.4 0.35 11.1 1.4 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_7 PF02591.15 EER26552.1 - 0.34 11.1 3.5 3.9 7.8 0.3 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain PHD_2 PF13831.6 EER26552.1 - 0.73 9.4 9.0 0.19 11.3 4.4 2.3 2 1 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 EER26552.1 - 1.5 8.9 3.8 4.5 7.3 3.8 1.8 1 1 0 1 1 1 0 zinc-ribbons C1_1 PF00130.22 EER26552.1 - 6.2 6.8 7.7 0.41 10.6 2.5 1.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Band_7 PF01145.25 EER26553.1 - 2e-23 83.3 5.6 2.5e-23 83.0 4.4 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EER26553.1 - 0.012 15.4 0.2 0.022 14.5 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Perilipin PF03036.16 EER26554.1 - 0.028 13.5 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Perilipin family Ribosomal_L27e PF01777.18 EER26555.1 - 1.3e-38 131.2 4.5 1.9e-38 130.7 4.5 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EER26555.1 - 0.0016 18.3 0.8 0.0054 16.7 0.1 2.2 2 0 0 2 2 2 1 KOW motif DUF826 PF05696.11 EER26555.1 - 0.17 12.0 0.2 0.3 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Baculo_PEP_C PF04513.12 EER26556.1 - 0.43 10.6 37.7 5.4 7.1 0.7 8.1 6 2 0 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus EDR1 PF14381.6 EER26556.1 - 0.55 9.9 8.9 0.15 11.8 0.3 3.3 2 1 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 TRAM_LAG1_CLN8 PF03798.16 EER26557.1 - 1.5e-52 178.3 17.6 2.5e-52 177.5 17.6 1.4 1 0 0 1 1 1 1 TLC domain SWIB PF02201.18 EER26558.1 - 6.5e-22 77.2 0.0 1.6e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF883 PF05957.13 EER26558.1 - 0.087 13.4 0.3 0.21 12.2 0.3 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RPN6_N PF18055.1 EER26559.1 - 1.9e-44 150.8 0.8 5.2e-44 149.4 0.1 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EER26559.1 - 3.9e-21 75.5 1.2 6.8e-21 74.8 0.2 2.0 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EER26559.1 - 2.4e-11 43.2 0.6 6.2e-11 41.8 0.6 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 EER26559.1 - 3.8e-07 30.3 16.2 0.0028 17.9 1.5 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EER26559.1 - 5.8e-06 25.9 4.9 4.8e-05 22.9 3.0 2.7 1 1 2 3 3 3 1 MalT-like TPR region DDRGK PF09756.9 EER26559.1 - 0.00036 20.2 0.2 0.00077 19.1 0.2 1.6 1 0 0 1 1 1 1 DDRGK domain TPR_2 PF07719.17 EER26559.1 - 0.0017 18.3 1.3 75 3.8 0.0 5.6 5 1 0 5 5 5 0 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 EER26559.1 - 0.0028 17.6 0.1 0.36 10.8 0.0 2.7 2 0 0 2 2 2 1 Crp-like helix-turn-helix domain TPR_7 PF13176.6 EER26559.1 - 0.0031 17.4 5.6 11 6.3 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EER26559.1 - 0.0034 17.1 0.8 34 4.5 0.0 4.9 5 1 0 5 5 5 0 Tetratricopeptide repeat DprA_WH PF17782.1 EER26559.1 - 0.026 14.6 0.0 0.32 11.1 0.0 2.5 2 0 0 2 2 2 0 DprA winged helix domain ABC_membrane_2 PF06472.15 EER26559.1 - 0.029 13.8 0.2 0.049 13.0 0.2 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 TPR_6 PF13174.6 EER26559.1 - 0.039 14.6 7.1 2.9 8.7 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Prefoldin_2 PF01920.20 EER26559.1 - 0.15 12.0 0.9 0.51 10.3 0.9 1.9 1 0 0 1 1 1 0 Prefoldin subunit DUF3496 PF12001.8 EER26559.1 - 0.99 9.8 3.8 2.4 8.6 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) SbsC_C PF18058.1 EER26559.1 - 1.5 9.0 5.6 0.39 11.0 0.2 2.6 3 0 0 3 3 3 0 SbsC C-terminal domain Sof1 PF04158.14 EER26560.1 - 8.6e-31 106.1 15.8 1.6e-30 105.2 15.8 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EER26560.1 - 3.6e-28 97.2 4.9 2e-05 25.3 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER26560.1 - 8.1e-09 35.7 0.1 0.068 13.5 0.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EER26560.1 - 0.00013 21.0 0.0 0.0094 14.9 0.0 2.8 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EER26560.1 - 0.0058 16.7 0.1 9.2 6.4 0.0 3.9 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 EER26560.1 - 0.027 14.3 0.1 0.13 12.2 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A adh_short PF00106.25 EER26561.1 - 4.8e-33 114.3 0.6 6.1e-33 113.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER26561.1 - 1.2e-25 90.5 0.1 1.7e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER26561.1 - 1.1e-07 32.0 0.2 2.2e-07 31.0 0.2 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EER26561.1 - 0.00022 20.7 0.2 0.00043 19.8 0.2 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GPDPase_memb PF10110.9 EER26561.1 - 0.0048 15.7 0.8 0.0095 14.7 0.8 1.4 1 0 0 1 1 1 1 Membrane domain of glycerophosphoryl diester phosphodiesterase F_actin_bind PF08919.10 EER26562.1 - 0.35 11.0 3.1 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 F-actin binding RNA_pol_Rpb4 PF03874.16 EER26563.1 - 4.7e-07 30.2 5.3 0.0018 18.6 0.2 2.5 2 1 0 2 2 2 2 RNA polymerase Rpb4 Nop PF01798.18 EER26564.1 - 4e-81 271.9 0.2 4e-81 271.9 0.2 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EER26564.1 - 4.1e-22 78.3 2.3 4.1e-22 78.3 2.3 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HTH_3 PF01381.22 EER26564.1 - 0.052 13.6 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix vATP-synt_AC39 PF01992.16 EER26565.1 - 1.6e-106 356.6 0.0 1.8e-106 356.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.6 EER26566.1 - 2.2e-38 132.1 1.7 7.7e-34 117.3 0.9 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EER26566.1 - 2.1e-33 114.7 0.0 5.8e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EER26566.1 - 3.1e-14 52.8 0.3 1.1e-13 50.9 0.2 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EER26566.1 - 0.0086 15.5 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase YukD PF08817.10 EER26567.1 - 0.003 18.2 0.0 0.0049 17.5 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 EER26567.1 - 0.0034 17.1 0.0 0.0054 16.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family PIG-H PF10181.9 EER26568.1 - 4.3e-27 93.8 0.7 9.3e-27 92.7 0.7 1.6 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.20 EER26569.1 - 3.1e-33 114.4 0.0 3.1e-32 111.2 0.0 2.3 2 0 0 2 2 2 1 tRNA pseudouridine synthase Amidoligase_2 PF12224.8 EER26570.1 - 1.5e-07 31.4 0.0 5.8e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Putative amidoligase enzyme Amidinotransf PF02274.17 EER26570.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Amidinotransferase Ribosomal_S2 PF00318.20 EER26571.1 - 4.8e-27 94.6 0.0 7.7e-15 54.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EER26571.1 - 4.5e-05 24.7 11.0 7.8e-05 24.0 11.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ribosomal_S15 PF00312.22 EER26572.1 - 2.4e-24 85.3 2.8 3e-24 85.0 0.3 2.3 3 0 0 3 3 3 1 Ribosomal protein S15 CorA PF01544.18 EER26573.1 - 2e-08 33.9 5.6 5.5e-08 32.5 2.2 2.1 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein 7TM_GPCR_Srw PF10324.9 EER26573.1 - 0.016 14.5 3.2 0.031 13.6 3.2 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srw Peptidase_U4 PF03419.13 EER26573.1 - 0.051 12.9 0.6 0.069 12.4 0.6 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA PIEZO PF15917.5 EER26574.1 - 0.37 10.2 0.7 7.4 6.0 0.0 2.8 3 0 0 3 3 3 0 Piezo DEAD PF00270.29 EER26575.1 - 5.8e-39 133.6 0.0 4.3e-38 130.8 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26575.1 - 1.3e-21 77.0 0.0 5e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EER26575.1 - 6.6e-21 74.3 0.0 1.2e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EER26575.1 - 0.0012 18.9 0.1 0.018 15.0 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3106 PF11304.8 EER26575.1 - 0.0096 16.4 10.2 0.0096 16.4 10.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3106) AAA_22 PF13401.6 EER26575.1 - 0.35 11.2 3.4 0.8 10.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain NEMP PF10225.9 EER26575.1 - 6.2 6.4 6.1 11 5.6 6.1 1.3 1 0 0 1 1 1 0 NEMP family Herpes_US9 PF06072.11 EER26576.1 - 0.037 13.9 0.7 0.23 11.4 0.0 2.5 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 XPG_I PF00867.18 EER26577.1 - 2.7e-20 72.5 0.0 6.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 EER26577.1 - 5e-14 53.1 1.8 5.5e-14 52.9 0.1 2.0 2 0 0 2 2 2 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 EER26577.1 - 1.7e-08 34.9 0.0 3.6e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain GCOM2 PF15328.6 EER26577.1 - 1.3 9.4 8.7 0.36 11.2 2.0 2.4 1 1 1 2 2 2 0 Putative GRINL1B complex locus protein 2 Actin PF00022.19 EER26578.1 - 5.9e-19 68.0 0.0 4.7e-12 45.2 0.0 3.1 3 1 0 3 3 3 2 Actin Aldose_epim PF01263.20 EER26580.1 - 1.1e-48 166.1 1.3 1.5e-48 165.6 1.3 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase CobU PF02283.16 EER26581.1 - 0.098 12.2 1.0 0.22 11.1 1.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Pkinase PF00069.25 EER26582.1 - 3e-11 43.2 0.0 1.7e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER26582.1 - 9.9e-07 28.3 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_72 PF03198.14 EER26583.1 - 6.8e-84 281.8 0.0 1.3e-83 280.9 0.0 1.3 1 1 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 EER26583.1 - 0.0071 15.5 0.0 0.0093 15.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sds3 PF08598.11 EER26585.1 - 2.4e-45 155.2 6.4 3e-44 151.7 4.2 2.2 2 0 0 2 2 2 2 Sds3-like YlqD PF11068.8 EER26585.1 - 0.15 12.4 1.5 0.8 10.1 0.6 2.6 1 1 1 2 2 2 0 YlqD protein FAM184 PF15665.5 EER26585.1 - 0.61 9.8 10.0 2.4 7.9 10.0 2.0 1 1 0 1 1 1 0 Family with sequence similarity 184, A and B Pkinase_Tyr PF07714.17 EER26586.1 - 0.27 10.5 0.1 0.36 10.1 0.1 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3530 PF12048.8 EER26588.1 - 0.1 12.0 0.1 0.59 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) CFEM PF05730.11 EER26589.1 - 3.6e-05 23.7 2.9 3.6e-05 23.7 2.9 2.3 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.10 EER26589.1 - 3.3 7.7 7.3 0.49 10.3 2.3 2.2 2 0 0 2 2 2 0 Thrombomodulin like fifth domain, EGF-like HTH_32 PF13565.6 EER26590.1 - 0.00064 20.3 0.2 0.023 15.3 0.0 2.4 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 EER26590.1 - 0.0089 16.3 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.6 EER26590.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.12 EER26590.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_38 PF13936.6 EER26590.1 - 0.11 12.3 0.0 0.36 10.6 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain SUZ PF12752.7 EER26591.1 - 2.3 9.0 7.1 1.4 9.7 0.4 3.3 2 0 0 2 2 2 0 SUZ domain DUF2752 PF10825.8 EER26592.1 - 0.083 13.0 0.5 0.13 12.3 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) BT1 PF03092.16 EER26592.1 - 0.16 10.2 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 BT1 family BTB PF00651.31 EER26593.1 - 3.2e-07 30.5 0.0 1.4e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 EER26593.1 - 0.004 17.3 0.0 0.007 16.5 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DUF3756 PF12581.8 EER26594.1 - 0.15 12.0 0.2 0.63 10.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Peptidase_S24 PF00717.23 EER26595.1 - 3.4e-08 33.3 0.1 6.6e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.26 EER26596.1 - 2.5e-43 147.1 0.0 2.8e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER26596.1 - 3.2e-09 36.6 0.0 4.7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EER26596.1 - 0.0053 17.0 0.0 0.0068 16.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EER26596.1 - 0.1 12.5 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF3786 PF12654.7 EER26596.1 - 0.11 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) RabGAP-TBC PF00566.18 EER26597.1 - 8.9e-35 120.3 0.0 2.7e-31 108.9 0.0 2.3 2 1 0 2 2 2 2 Rab-GTPase-TBC domain BCS1_N PF08740.11 EER26599.1 - 1.1e-49 169.0 0.3 1.5e-49 168.6 0.3 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EER26599.1 - 1.5e-17 64.2 0.0 2.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EER26599.1 - 2.7e-05 24.6 0.5 0.00015 22.2 0.1 2.4 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 EER26599.1 - 0.001 18.3 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EER26599.1 - 0.0065 16.6 0.0 0.024 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EER26599.1 - 0.0082 16.4 0.0 0.058 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EER26599.1 - 0.011 15.8 0.0 0.028 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EER26599.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 EER26599.1 - 0.015 15.1 0.0 0.068 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EER26599.1 - 0.02 15.4 0.0 0.044 14.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EER26599.1 - 0.027 14.2 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EER26599.1 - 0.037 14.4 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.6 EER26599.1 - 0.038 14.5 0.0 0.085 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EER26599.1 - 0.12 12.1 0.0 0.83 9.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain ATPase PF06745.13 EER26599.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 EER26599.1 - 0.23 11.3 0.0 0.49 10.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Lactamase_B_2 PF12706.7 EER26600.1 - 2.7e-26 92.3 0.0 4.2e-25 88.5 0.0 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EER26600.1 - 8.5e-11 42.0 0.0 2.1e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EER26600.1 - 0.00025 21.1 3.1 0.048 13.6 0.3 2.9 3 1 0 3 3 3 2 Metallo-beta-lactamase superfamily Cpn60_TCP1 PF00118.24 EER26601.1 - 2.8e-172 573.8 1.1 3.2e-172 573.6 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Alba PF01918.21 EER26601.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Alba DUF1168 PF06658.12 EER26602.1 - 1.9e-41 141.0 8.5 2.6e-41 140.6 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 EER26602.1 - 0.00089 18.5 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Lyase, catalytic Peptidase_S49_N PF08496.10 EER26602.1 - 0.048 13.7 4.5 0.066 13.3 4.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PPL5 PF18168.1 EER26602.1 - 0.11 11.7 2.1 0.15 11.3 2.1 1.1 1 0 0 1 1 1 0 Prim-pol family 5 DUF5401 PF17380.2 EER26602.1 - 1 7.4 13.7 1.3 7.0 13.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Presenilin PF01080.17 EER26602.1 - 1.1 8.0 2.5 0.98 8.1 2.5 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EER26602.1 - 6.1 5.0 8.6 7.9 4.6 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein PhoD PF09423.10 EER26603.1 - 8.3e-104 347.4 0.4 1.2e-103 346.9 0.4 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EER26603.1 - 1.3e-27 96.2 0.0 2.1e-25 89.1 0.0 2.5 1 1 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EER26603.1 - 0.066 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain zf-PARP PF00645.18 EER26604.1 - 2.6e-17 63.4 1.5 6.1e-17 62.3 1.5 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region RR_TM4-6 PF06459.12 EER26604.1 - 6 6.6 14.9 9.9 5.9 14.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Kinesin PF00225.23 EER26605.1 - 5.1e-57 193.3 0.0 7.4e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EER26605.1 - 7.2e-12 45.5 0.0 1.3e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding bZIP_2 PF07716.15 EER26605.1 - 0.00066 19.7 0.8 0.00066 19.7 0.8 2.2 2 0 0 2 2 2 1 Basic region leucine zipper AAA_13 PF13166.6 EER26605.1 - 0.0078 14.9 2.9 0.012 14.3 2.9 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EER26605.1 - 0.013 15.6 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain TPR_11 PF13414.6 EER26606.1 - 0.00048 19.7 1.2 0.085 12.6 0.4 3.4 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 EER26606.1 - 0.0015 19.2 2.8 6.1 7.9 0.0 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EER26606.1 - 0.033 14.0 10.6 2.1 8.3 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EER26606.1 - 0.55 10.5 11.9 2.1 8.7 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EER26607.1 - 3.6e-148 493.8 0.0 4.8e-148 493.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 EER26607.1 - 1.3e-07 31.2 2.5 0.01 15.8 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EER26607.1 - 3.7e-07 29.7 0.3 0.17 11.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EER26607.1 - 1.4e-06 28.7 0.5 0.11 13.0 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EER26607.1 - 2.7e-05 24.6 2.3 2.6 9.1 0.0 5.1 3 2 3 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EER26607.1 - 8.4e-05 22.5 0.1 0.55 10.6 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EER26607.1 - 0.00011 22.4 4.6 0.26 11.6 0.2 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EER26607.1 - 0.00014 22.0 0.2 0.14 12.4 0.0 2.8 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER26607.1 - 0.00059 19.7 1.3 3.4 7.9 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EER26607.1 - 0.00092 19.4 3.1 0.77 10.0 0.2 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EER26607.1 - 0.051 14.2 0.7 2.2 9.0 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EER26607.1 - 0.11 11.7 1.7 0.49 9.6 0.3 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat ERCC4 PF02732.15 EER26609.1 - 1.2e-25 90.6 0.0 1.8e-25 90.0 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain E1-E2_ATPase PF00122.20 EER26610.1 - 5.2e-50 169.5 0.3 2.6e-49 167.2 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.26 EER26610.1 - 4.5e-42 142.3 3.5 4.9e-13 49.3 0.0 4.8 4 1 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EER26610.1 - 4.5e-34 118.6 0.2 8.6e-34 117.7 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EER26610.1 - 2.4e-05 24.2 2.2 0.0094 15.7 0.5 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase DAHP_snth_FXD PF18152.1 EER26610.1 - 0.0078 16.0 0.4 2.5 8.0 0.0 3.5 5 0 0 5 5 5 1 DAHP synthase ferredoxin-like domain HAD PF12710.7 EER26610.1 - 0.04 14.3 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase 7TM_GPCR_Sri PF10327.9 EER26610.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri BPD_transp_1 PF00528.22 EER26610.1 - 0.13 12.0 6.2 0.26 11.0 0.6 2.7 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component TFIIB PF00382.19 EER26611.1 - 3.2e-33 113.6 6.1 6.6e-18 64.5 0.1 3.3 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EER26611.1 - 4e-26 91.3 2.6 1.9e-25 89.1 0.0 3.1 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EER26611.1 - 7.9e-05 22.1 2.1 0.00018 21.0 2.1 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EER26611.1 - 0.016 15.0 0.1 1.7 8.4 0.0 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain IBR PF01485.21 EER26611.1 - 0.22 11.8 2.6 0.31 11.3 1.6 1.7 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain CENP-B_dimeris PF09026.10 EER26611.1 - 6.3 7.3 12.2 18 5.8 12.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Metallophos PF00149.28 EER26612.1 - 1.7e-13 51.6 0.8 3.1e-13 50.7 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EER26612.1 - 7.4e-05 23.0 0.0 0.00025 21.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPT PF03151.16 EER26614.1 - 2.7e-25 89.3 19.3 3.3e-25 89.0 19.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EER26614.1 - 1.4e-05 24.4 21.2 2.4e-05 23.7 21.2 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EER26614.1 - 0.0091 16.2 31.8 0.31 11.2 10.8 2.4 2 0 0 2 2 2 2 EamA-like transporter family APH PF01636.23 EER26615.1 - 2.5e-13 50.5 0.1 3.4e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EER26615.1 - 0.13 11.4 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.20 EER26615.1 - 0.2 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Y1_Tnp PF01797.16 EER26617.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Transposase IS200 like NAD_binding_8 PF13450.6 EER26618.1 - 4.2e-08 33.3 0.0 1.1e-07 32.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EER26618.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EER26618.1 - 0.0017 17.6 0.1 0.052 12.8 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER26618.1 - 0.02 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EER26618.1 - 0.024 13.9 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 EER26618.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EER26618.1 - 0.057 13.4 0.6 0.4 10.6 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EER26618.1 - 0.067 12.5 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.24 EER26618.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 EER26618.1 - 0.094 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 EER26618.1 - 0.099 11.7 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pkinase PF00069.25 EER26619.1 - 7.3e-67 225.5 0.0 1e-66 225.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26619.1 - 4.3e-32 111.4 0.0 2.1e-31 109.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EER26619.1 - 0.0011 18.0 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EER26619.1 - 0.0027 17.7 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EER26619.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EER26619.1 - 0.07 12.4 0.0 0.6 9.4 0.0 2.1 2 0 0 2 2 2 0 Kinase-like tRNA-synt_2b PF00587.25 EER26621.1 - 3.3e-17 63.0 0.0 4.7e-16 59.3 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EER26621.1 - 4.8e-07 30.0 4.1 1.1e-06 28.8 4.1 1.6 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 EER26621.1 - 0.019 15.2 5.9 0.019 15.2 5.9 1.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) LidA_Long_CC PF18641.1 EER26621.1 - 0.11 12.6 3.7 0.18 11.8 3.7 1.3 1 0 0 1 1 1 0 LidA long coiled-coil domain Exonuc_VII_L PF02601.15 EER26621.1 - 0.62 9.6 3.3 1 8.9 3.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 EER26621.1 - 0.8 9.9 4.8 2.9 8.2 4.7 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EER26621.1 - 1.2 8.0 6.5 2.2 7.1 6.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein FapA PF03961.13 EER26621.1 - 1.4 7.4 3.4 2 6.9 3.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 EER26621.1 - 2.7 7.3 8.6 0.52 9.6 5.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Cytochrom_B561 PF03188.16 EER26622.1 - 8.7e-14 51.8 4.3 8.7e-14 51.8 4.3 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Frag1 PF10277.9 EER26622.1 - 0.002 17.7 3.0 0.003 17.1 3.0 1.2 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4079 PF13301.6 EER26622.1 - 0.026 14.7 7.9 0.33 11.1 7.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) SLATT_fungal PF18142.1 EER26622.1 - 0.048 13.6 0.3 7.8 6.5 0.1 2.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain GWT1 PF06423.12 EER26622.1 - 0.088 12.9 1.2 0.28 11.3 0.2 2.0 1 1 1 2 2 2 0 GWT1 UPF0220 PF05255.11 EER26622.1 - 0.18 11.3 2.7 0.23 11.0 0.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0220) Ni_hydr_CYTB PF01292.20 EER26622.1 - 0.27 10.8 8.1 2.1 7.9 8.1 2.5 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 AzlD PF05437.12 EER26622.1 - 0.29 11.3 5.8 0.075 13.2 1.6 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) PepSY_TM PF03929.16 EER26622.1 - 9.2 5.8 7.4 23 4.5 0.8 2.8 1 1 2 3 3 3 0 PepSY-associated TM region Allantoicase PF03561.15 EER26623.1 - 3.4e-89 296.2 0.0 5e-44 149.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.26 EER26624.1 - 4.8e-23 81.8 0.5 2.1e-22 79.8 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EER26624.1 - 1e-21 77.2 0.0 2.5e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EER26624.1 - 1.8e-16 59.9 0.2 7.8e-16 57.9 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EER26624.1 - 1.5e-10 41.2 0.3 0.0051 17.1 0.0 3.8 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 EER26624.1 - 1.1e-05 25.6 0.0 4.4e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EER26624.1 - 0.0022 18.2 0.0 0.27 11.5 0.0 3.3 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 EER26624.1 - 0.0054 16.7 0.0 3.3 7.7 0.0 3.2 3 0 0 3 3 3 2 PAS fold HATPase_c PF02518.26 EER26625.1 - 1.7e-30 105.8 0.0 4.9e-30 104.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EER26625.1 - 3.1e-20 72.4 0.1 6.8e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EER26625.1 - 1.5e-18 66.5 1.7 7.8e-18 64.3 0.0 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EER26625.1 - 9e-11 42.4 1.4 7.6e-10 39.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain GAF_2 PF13185.6 EER26625.1 - 2.8e-09 37.4 0.0 8e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EER26625.1 - 5.7e-07 30.2 0.0 1.7e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EER26625.1 - 0.00038 20.8 0.0 0.0011 19.4 0.0 1.8 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 EER26625.1 - 0.00039 19.9 0.0 0.0028 17.1 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain HATPase_c_3 PF13589.6 EER26625.1 - 0.00048 20.0 0.0 0.0016 18.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NB-ARC PF00931.22 EER26625.1 - 0.0046 16.2 0.1 2.6 7.2 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain GTP_cyclohydroI PF01227.22 EER26625.1 - 0.015 14.7 0.4 0.44 9.9 0.4 2.5 2 0 0 2 2 2 0 GTP cyclohydrolase I LepB_GAP_C PF18227.1 EER26625.1 - 0.025 15.1 0.4 0.18 12.3 0.2 2.5 2 0 0 2 2 2 0 LepB GAP domain C-terminal subdomain MeaB PF03308.16 EER26625.1 - 0.038 13.0 0.0 0.075 12.0 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 EER26625.1 - 0.071 12.4 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EER26625.1 - 0.081 12.8 0.1 7.7 6.4 0.0 3.4 3 0 0 3 3 3 0 NACHT domain DUF1217 PF06748.12 EER26625.1 - 0.15 12.1 1.6 0.43 10.6 1.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) KxDL PF10241.9 EER26626.1 - 2.3e-29 101.5 0.8 2.9e-29 101.2 0.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF4407 PF14362.6 EER26626.1 - 0.034 13.5 0.4 0.04 13.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fzo_mitofusin PF04799.13 EER26626.1 - 0.058 12.9 0.4 0.079 12.5 0.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region AAA PF00004.29 EER26627.1 - 8e-53 178.4 0.0 1.1e-38 132.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER26627.1 - 7e-11 41.8 0.0 1.6e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain CDC48_2 PF02933.17 EER26627.1 - 2.7e-10 39.9 0.1 4.1e-09 36.1 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 EER26627.1 - 3.2e-09 37.2 0.0 0.00042 20.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EER26627.1 - 4.8e-09 36.8 0.0 0.0028 18.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.13 EER26627.1 - 2.1e-08 33.8 0.0 0.0046 16.2 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain CDC48_N PF02359.18 EER26627.1 - 7.1e-08 32.5 0.0 1.6e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_5 PF07728.14 EER26627.1 - 8.1e-08 32.4 0.1 0.0023 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EER26627.1 - 1.6e-07 31.2 0.0 0.022 14.5 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EER26627.1 - 2.1e-07 30.5 0.1 0.0048 16.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EER26627.1 - 2.7e-07 30.5 0.0 0.0081 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EER26627.1 - 2.8e-07 30.8 0.0 3.6e-05 24.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EER26627.1 - 7.4e-07 29.3 0.0 0.11 12.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EER26627.1 - 2e-06 28.1 0.0 0.059 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EER26627.1 - 2.2e-06 28.2 0.0 0.015 15.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 EER26627.1 - 2.3e-06 27.9 0.0 0.034 14.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 EER26627.1 - 2.2e-05 24.3 0.0 0.093 12.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EER26627.1 - 2.6e-05 23.8 0.1 0.021 14.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 EER26627.1 - 6.1e-05 22.3 0.5 0.12 11.5 0.0 2.6 3 0 0 3 3 2 2 NB-ARC domain TsaE PF02367.17 EER26627.1 - 6.2e-05 23.0 0.0 0.076 13.0 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EER26627.1 - 6.7e-05 22.4 0.2 0.026 13.9 0.2 2.4 2 0 0 2 2 2 1 KaiC AAA_3 PF07726.11 EER26627.1 - 0.00012 21.9 0.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EER26627.1 - 0.00014 21.9 0.4 0.15 12.0 0.0 3.1 3 0 0 3 3 2 1 NACHT domain AAA_11 PF13086.6 EER26627.1 - 0.00021 21.2 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EER26627.1 - 0.00023 20.7 0.0 0.41 10.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 EER26627.1 - 0.00024 21.7 0.1 0.023 15.2 0.1 2.4 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.6 EER26627.1 - 0.00024 20.7 0.3 0.63 9.6 0.1 2.9 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EER26627.1 - 0.00049 19.8 0.0 0.53 10.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EER26627.1 - 0.00089 19.5 0.0 0.7 10.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EER26627.1 - 0.0019 18.0 0.2 0.43 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EER26627.1 - 0.002 18.4 0.2 0.73 10.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.6 EER26627.1 - 0.0026 18.2 0.1 0.97 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EER26627.1 - 0.0028 17.6 0.4 10 6.0 0.0 3.3 3 1 1 4 4 3 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EER26627.1 - 0.0039 16.5 0.1 1.4 8.1 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 EER26627.1 - 0.0068 15.8 0.1 5.4 6.4 0.0 3.6 3 1 1 4 4 4 0 Bacterial TniB protein ResIII PF04851.15 EER26627.1 - 0.011 15.7 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 EER26627.1 - 0.014 14.5 0.0 0.5 9.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KTI12 PF08433.10 EER26627.1 - 0.025 14.0 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EER26627.1 - 0.031 13.5 0.0 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 EER26627.1 - 0.031 13.9 0.1 2.6 7.6 0.0 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EER26627.1 - 0.033 14.1 0.1 11 5.9 0.1 2.9 2 0 0 2 2 2 0 NTPase DEAD PF00270.29 EER26627.1 - 0.062 13.1 0.1 29 4.4 0.0 3.7 3 1 1 4 4 4 0 DEAD/DEAH box helicase DAP3 PF10236.9 EER26627.1 - 0.073 12.2 0.1 7.2 5.7 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 EER26627.1 - 0.09 12.5 0.0 8.7 6.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain Hydin_ADK PF17213.3 EER26627.1 - 0.16 12.3 0.1 2.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Rad17 PF03215.15 EER26627.1 - 0.16 11.9 0.0 3.2 7.6 0.0 2.6 3 0 0 3 3 2 0 Rad17 P-loop domain Vps4_C PF09336.10 EER26627.1 - 0.18 11.8 0.0 0.56 10.2 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Cir_N PF10197.9 EER26628.1 - 9.6e-05 22.5 5.8 9.6e-05 22.5 5.8 4.4 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Methyltransf_25 PF13649.6 EER26629.1 - 1.1e-09 38.8 0.1 2.6e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EER26629.1 - 1.5e-08 34.4 0.1 2.6e-08 33.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EER26629.1 - 8.9e-08 32.7 0.1 1.9e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER26629.1 - 4.5e-07 29.8 0.0 9.4e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EER26629.1 - 4.6e-05 23.4 0.1 9.5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER26629.1 - 0.00011 22.0 0.0 0.00027 20.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER26629.1 - 0.00024 20.7 0.1 0.00042 19.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 EER26629.1 - 0.00038 19.5 0.0 0.00056 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 EER26629.1 - 0.026 13.9 0.1 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 EER26629.1 - 0.028 15.1 0.0 0.084 13.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 EER26629.1 - 0.089 13.8 0.0 0.22 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EER26629.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mo25 PF08569.11 EER26630.1 - 1.9e-130 435.0 0.1 2.2e-130 434.8 0.1 1.0 1 0 0 1 1 1 1 Mo25-like TPP_enzyme_N PF02776.18 EER26631.1 - 1.5e-41 141.9 0.0 4.5e-41 140.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EER26631.1 - 8e-19 67.9 0.0 2.9e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EER26631.1 - 1.3e-14 54.1 0.0 2.3e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.6 EER26631.1 - 0.065 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase RabGAP-TBC PF00566.18 EER26632.1 - 3.3e-36 125.0 0.0 4.9e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kelch_3 PF13415.6 EER26632.1 - 0.26 11.6 1.0 7.2 7.0 0.1 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain DIL PF01843.19 EER26634.1 - 1.6e-31 108.6 0.3 3.4e-31 107.6 0.3 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 EER26634.1 - 2.4e-14 53.7 0.1 1.5e-13 51.1 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER26634.1 - 6e-11 42.4 0.0 1.4e-06 28.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EER26634.1 - 9.7e-08 32.1 0.1 0.086 13.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EER26634.1 - 3.4e-07 30.7 0.1 6.2e-05 23.5 0.1 3.6 2 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER26634.1 - 7.3e-07 29.0 0.3 0.034 14.7 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat RasGEF PF00617.19 EER26635.1 - 1e-40 139.8 2.2 1.3e-40 139.5 0.6 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EER26635.1 - 7e-14 51.9 0.1 1.7e-13 50.7 0.1 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Arginosuc_synth PF00764.19 EER26636.1 - 2.8e-152 507.5 0.0 3.4e-152 507.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EER26636.1 - 0.0052 16.3 0.0 0.0083 15.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EER26636.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Glyco_hydro_114 PF03537.13 EER26636.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 MAD PF05557.13 EER26637.1 - 2.1e-56 191.7 82.3 4.5e-47 160.8 83.4 2.9 2 1 0 2 2 2 2 Mitotic checkpoint protein Phage_tail_NK PF16532.5 EER26637.1 - 0.13 11.8 0.1 0.46 10.1 0.0 1.9 2 0 0 2 2 2 0 Sf6-type phage tail needle knob or tip of some Caudovirales CC2-LZ PF16516.5 EER26637.1 - 0.48 10.8 0.1 0.48 10.8 0.1 8.0 4 2 3 7 7 7 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator WD40_alt PF14077.6 EER26637.1 - 0.69 9.8 5.4 8.4 6.4 0.1 3.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif Spc7 PF08317.11 EER26637.1 - 1.2 8.0 90.7 0.1 11.4 4.1 5.7 3 2 3 6 6 6 0 Spc7 kinetochore protein ZYG-11_interact PF05884.12 EER26637.1 - 8.4 5.7 5.1 14 5.0 4.4 1.8 1 1 0 1 1 1 0 Interactor of ZYG-11 Peptidase_M20 PF01546.28 EER26638.1 - 2.3e-29 102.6 0.4 3.3e-29 102.1 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EER26638.1 - 2.1e-18 66.2 0.1 5.5e-18 64.9 0.1 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EER26638.1 - 1.7e-05 24.6 0.0 4.5e-05 23.2 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M28 adh_short PF00106.25 EER26638.1 - 0.088 12.3 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase muHD PF10291.9 EER26639.1 - 1.4e-73 247.6 0.1 2.1e-73 247.0 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EER26639.1 - 3.2e-08 33.7 1.9 1.8e-07 31.3 0.0 3.1 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain NUFIP1 PF10453.9 EER26639.1 - 0.54 10.2 2.7 0.49 10.3 0.5 2.0 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Pkinase PF00069.25 EER26640.1 - 1.9e-42 145.4 0.0 2.6e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26640.1 - 1.8e-16 60.2 0.0 2.6e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER26640.1 - 2.4e-07 30.9 0.1 0.00017 21.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family KIX_2 PF16987.5 EER26640.1 - 0.00084 19.3 0.1 0.0015 18.5 0.1 1.4 1 0 0 1 1 1 1 KIX domain Pkinase_fungal PF17667.1 EER26640.1 - 0.0073 15.1 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EER26640.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EER26640.1 - 0.057 12.8 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EER26640.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SH3_9 PF14604.6 EER26641.1 - 8.5e-10 38.3 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EER26641.1 - 1.5e-06 27.7 0.0 2.3e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EER26641.1 - 8e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 EER26641.1 - 0.17 12.0 5.4 0.029 14.5 1.0 1.9 2 0 0 2 2 2 0 Podoplanin OPT PF03169.15 EER26642.1 - 1.5e-165 552.4 12.3 1.8e-165 552.1 12.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Rav1p_C PF12234.8 EER26643.1 - 2e-284 945.0 3.9 6.1e-282 936.8 2.8 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 EER26643.1 - 1.1 10.2 11.4 1.7 9.6 0.1 5.2 6 0 0 6 6 6 0 WD domain, G-beta repeat Sfi1 PF08457.10 EER26644.1 - 7.4e-208 691.7 97.8 1.8e-207 690.4 86.9 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein tRNA-synt_1 PF00133.22 EER26645.1 - 3.2e-224 745.7 0.0 5.8e-224 744.8 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EER26645.1 - 3e-25 89.0 0.0 8.4e-25 87.5 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EER26645.1 - 1.4e-13 50.4 0.0 3.7e-06 25.9 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EER26645.1 - 0.04 13.3 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.14 EER26646.1 - 1.3e-112 376.0 0.0 6.4e-112 373.7 0.0 2.1 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EER26646.1 - 9.8e-21 74.4 26.0 9.8e-21 74.4 26.0 4.0 2 1 2 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.21 EER26646.1 - 0.0001 22.0 41.1 0.0017 18.0 28.8 2.2 1 1 1 2 2 2 2 Intermediate filament protein Spc7 PF08317.11 EER26646.1 - 0.056 12.3 37.5 1.1 8.1 6.9 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Lectin_N PF03954.14 EER26646.1 - 0.15 11.8 6.0 1.1 9.0 2.5 3.1 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain LepA_C PF06421.12 EER26646.1 - 0.16 12.1 1.4 0.4 10.9 0.1 2.3 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus HsbA PF12296.8 EER26646.1 - 0.17 12.3 0.7 1.5 9.2 0.7 2.7 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Fez1 PF06818.15 EER26646.1 - 0.33 11.4 35.5 0.1 13.0 21.0 2.4 1 1 1 2 2 2 0 Fez1 Leu_zip PF15294.6 EER26646.1 - 0.43 10.1 29.2 0.29 10.6 18.3 2.7 1 1 1 2 2 2 0 Leucine zipper Lebercilin PF15619.6 EER26646.1 - 0.67 9.6 42.6 0.044 13.4 14.4 3.4 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease She9_MDM33 PF05546.11 EER26646.1 - 0.68 9.7 19.9 0.058 13.2 3.1 3.6 1 1 1 3 3 3 0 She9 / Mdm33 family DUF3584 PF12128.8 EER26646.1 - 0.88 7.0 35.8 1.3 6.4 35.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.12 EER26646.1 - 3.4 7.7 38.7 4 7.5 8.3 3.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4094 PF13334.6 EER26646.1 - 3.8 8.0 6.3 13 6.3 0.1 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Tropomyosin PF00261.20 EER26646.1 - 5.4 6.3 44.5 0.57 9.5 30.8 3.0 1 1 2 3 3 2 0 Tropomyosin ATG16 PF08614.11 EER26646.1 - 7.7 6.7 38.8 0.99 9.6 20.0 3.2 1 1 1 2 2 1 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 EER26646.1 - 8.1 6.5 32.6 2.4 8.2 14.5 3.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding XRN_M PF17846.1 EER26647.1 - 8.7e-156 519.3 1.9 1.2e-155 518.8 0.0 2.1 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EER26647.1 - 1.1e-100 336.1 1.0 9.2e-100 333.0 0.0 2.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 EER26647.1 - 0.031 14.4 1.4 0.058 13.5 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle EPSP_synthase PF00275.20 EER26648.1 - 2.5e-128 428.3 0.0 3.5e-128 427.9 0.0 1.1 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EER26648.1 - 7.4e-99 330.2 0.0 1.2e-98 329.5 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EER26648.1 - 1.9e-57 195.2 0.0 7.9e-57 193.1 0.0 2.1 3 0 0 3 3 3 1 Type I 3-dehydroquinase SKI PF01202.22 EER26648.1 - 4.6e-37 127.6 0.3 1.3e-36 126.1 0.0 1.9 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EER26648.1 - 3.8e-25 88.0 0.0 9e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EER26648.1 - 9.9e-08 31.6 1.8 1.7e-07 30.9 0.5 2.0 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 EER26648.1 - 5.5e-06 26.3 0.1 2.3e-05 24.2 0.1 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EER26648.1 - 0.00084 19.4 0.0 0.0028 17.7 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Exo5 PF09810.9 EER26649.1 - 1.2e-133 446.2 0.0 2e-133 445.5 0.0 1.3 2 0 0 2 2 2 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EER26649.1 - 0.0093 15.9 0.3 7.2 6.4 0.0 3.4 4 0 0 4 4 4 2 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.12 EER26650.1 - 5e-15 55.5 3.5 5.1e-15 55.4 0.4 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family Histone PF00125.24 EER26651.1 - 7e-52 175.2 2.7 7.8e-52 175.1 2.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EER26651.1 - 5.8e-06 26.6 0.0 9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EER26651.1 - 3.8e-05 23.8 0.1 7.4e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EER26651.1 - 0.00013 22.6 1.4 0.00015 22.3 1.4 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EER26651.1 - 0.0049 17.1 0.9 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EER26651.1 - 0.027 14.6 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EER26652.1 - 2.7e-09 37.1 0.1 3.2e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EER26652.1 - 3.4e-06 27.5 0.2 4e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EER26652.1 - 3.9e-05 23.7 0.1 5.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EER26652.1 - 9.7e-05 22.6 0.1 0.00016 21.8 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EER26652.1 - 0.00034 20.9 0.1 0.00051 20.4 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EER26652.1 - 0.0063 16.6 0.0 0.0076 16.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit HIGH_NTase1_ass PF16581.5 EER26652.1 - 0.04 13.9 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Bromo_TP PF07524.13 EER26652.1 - 0.047 13.7 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TF_Zn_Ribbon PF08271.12 EER26653.1 - 0.34 10.5 1.9 0.64 9.6 1.9 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2076 PF09849.9 EER26653.1 - 7 6.6 11.1 65 3.4 8.7 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-C2H2 PF00096.26 EER26654.1 - 1.5e-06 28.3 23.8 0.00018 21.8 1.4 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER26654.1 - 1.4e-05 25.5 10.9 0.034 15.0 1.1 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger DUF3445 PF11927.8 EER26655.1 - 1.1e-79 267.3 0.0 1.4e-79 266.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.17 EER26656.1 - 3.4e-61 207.7 10.9 3.9e-61 207.5 10.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PDR_assoc PF08370.11 EER26656.1 - 0.81 9.5 4.9 0.93 9.3 0.3 2.8 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Gar1 PF04410.14 EER26657.1 - 6.8e-48 162.3 1.1 1.5e-47 161.3 1.1 1.5 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Bact_lectin PF18483.1 EER26657.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial lectin AF-4 PF05110.13 EER26657.1 - 0.17 9.9 9.1 0.33 9.0 9.1 1.5 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 EER26657.1 - 0.21 11.2 4.7 0.059 13.0 0.4 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CSRNP_N PF16019.5 EER26657.1 - 1.8 8.5 4.3 1 9.2 1.5 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus IMUP PF15761.5 EER26657.1 - 2.4 8.9 8.4 7 7.4 5.2 2.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein PRP3 PF08572.10 EER26658.1 - 2.6e-74 249.7 2.4 2.6e-74 249.7 2.4 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EER26658.1 - 5.5e-46 156.3 0.1 5.5e-46 156.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) SF1-HH PF16275.5 EER26658.1 - 8 6.8 11.2 5 7.5 0.1 4.3 4 0 0 4 4 4 0 Splicing factor 1 helix-hairpin domain RNA_pol_Rpb1_5 PF04998.17 EER26659.1 - 1.5e-83 280.4 0.2 3.8e-83 279.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EER26659.1 - 2.5e-67 226.3 0.3 7.7e-67 224.7 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EER26659.1 - 1.4e-34 119.3 0.0 1.1e-33 116.4 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EER26659.1 - 9.9e-26 90.8 2.5 1.8e-23 83.3 1.8 3.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EER26659.1 - 3.1e-16 59.3 0.0 1.3e-15 57.2 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 SDA1 PF05285.12 EER26659.1 - 0.13 11.6 25.2 0.55 9.6 21.5 2.4 2 0 0 2 2 2 0 SDA1 DEAD_2 PF06733.15 EER26660.1 - 4.7e-57 192.4 0.4 7.8e-57 191.7 0.4 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EER26660.1 - 3.3e-50 170.4 2.3 5.6e-45 153.4 0.8 2.5 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EER26660.1 - 2.4e-43 148.3 0.0 6.9e-43 146.8 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EER26660.1 - 0.00045 20.3 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EER26660.1 - 0.0015 18.4 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 EER26660.1 - 0.033 12.9 0.0 0.22 10.2 0.0 2.0 1 1 0 1 1 1 0 SNF2 family N-terminal domain DUF2075 PF09848.9 EER26660.1 - 0.078 12.2 0.0 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EER26660.1 - 0.11 12.8 1.0 5.8 7.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain zf-RING_2 PF13639.6 EER26661.1 - 3.3e-08 33.7 8.1 3.3e-08 33.7 8.1 2.2 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 EER26661.1 - 3.4e-05 23.9 7.2 4.2e-05 23.6 5.5 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EER26661.1 - 3.4e-05 23.8 1.2 0.00011 22.1 1.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EER26661.1 - 0.00016 21.9 7.1 0.00043 20.5 7.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EER26661.1 - 0.00035 20.3 7.5 0.00035 20.3 7.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER26661.1 - 0.00059 19.7 9.6 0.00059 19.7 9.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EER26661.1 - 0.0064 16.4 5.4 0.016 15.1 5.4 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 EER26661.1 - 0.022 14.4 5.0 0.051 13.2 5.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EER26661.1 - 0.032 14.6 7.5 0.066 13.5 7.5 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EER26661.1 - 0.085 13.0 7.4 0.17 12.0 7.4 1.5 1 0 0 1 1 1 0 RING-variant domain DCB PF16213.5 EER26661.1 - 0.097 12.3 2.0 2.8 7.6 0.2 3.1 3 0 0 3 3 3 0 Dimerisation and cyclophilin-binding domain of Mon2 zf-RING_9 PF13901.6 EER26661.1 - 1 9.3 5.5 2.5 8.0 5.5 1.6 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 EER26661.1 - 1.1 9.3 7.0 2.2 8.2 7.0 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 EER26661.1 - 2 8.3 7.7 0.22 11.3 3.2 1.8 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 EER26661.1 - 2 8.3 5.6 37 4.2 5.6 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EER26661.1 - 4.5 7.2 5.9 12 5.8 5.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LCM PF04072.14 EER26662.1 - 2.8e-24 86.1 0.0 4.5e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.13 EER26663.1 - 1.8e-83 279.8 8.4 2.4e-83 279.4 8.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) SDA1 PF05285.12 EER26663.1 - 0.02 14.3 3.0 0.027 13.9 3.0 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 EER26663.1 - 0.18 12.2 14.1 0.31 11.4 14.1 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.10 EER26663.1 - 0.34 10.2 7.8 0.47 9.7 7.8 1.1 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EER26663.1 - 0.4 9.9 5.5 0.64 9.3 5.5 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 EER26663.1 - 2.5 6.2 6.1 3.3 5.8 6.1 1.0 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 EER26663.1 - 3 6.6 4.5 4.1 6.2 4.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ATP_transf PF09830.9 EER26664.1 - 2.7e-15 56.3 0.0 4.9e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase zf-C3HC4 PF00097.25 EER26665.1 - 8.2e-10 38.4 4.7 5.3e-09 35.8 4.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER26665.1 - 5.9e-07 29.3 5.2 6.6e-05 22.7 1.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER26665.1 - 8e-06 25.8 2.4 8e-06 25.8 2.4 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EER26665.1 - 2.1e-05 24.7 11.6 0.00038 20.7 11.6 2.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER26665.1 - 2.2e-05 24.2 6.5 3.2e-05 23.7 1.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 EER26665.1 - 0.00029 21.5 0.5 0.0096 16.6 0.1 2.4 2 0 0 2 2 2 1 Torus domain Prok-RING_4 PF14447.6 EER26665.1 - 0.00033 20.4 7.5 0.037 13.9 3.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EER26665.1 - 0.00053 20.1 6.0 0.0029 17.7 6.1 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EER26665.1 - 0.0014 18.5 5.4 0.0046 16.9 5.4 1.9 1 1 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EER26665.1 - 0.0096 15.5 1.3 0.0096 15.5 1.3 2.4 4 0 0 4 4 3 1 Zinc-ribbon, C4HC2 type COG7 PF10191.9 EER26665.1 - 0.11 10.7 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) zf-rbx1 PF12678.7 EER26665.1 - 0.39 11.0 12.7 13 6.2 12.7 2.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-CCCH_3 PF15663.5 EER26665.1 - 1.4 9.2 5.0 0.53 10.5 0.2 2.6 3 1 0 3 3 3 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EER26665.1 - 2.6 8.6 18.6 1.1 9.8 3.4 3.6 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EER26665.1 - 4.3 7.2 15.5 0.8 9.6 5.4 3.3 3 0 0 3 3 3 0 CCCH-type zinc finger Kinesin PF00225.23 EER26666.1 - 3.1e-49 167.7 0.0 1.1e-25 90.3 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EER26666.1 - 1.2e-08 35.0 0.0 2.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding DUF4846 PF16138.5 EER26666.1 - 0.05 13.1 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (4846) zf_Rg PF17915.1 EER26667.1 - 0.0094 15.3 0.2 0.0094 15.3 0.2 1.8 1 1 1 2 2 2 1 Reverse gyrase zinc finger Zn_clus PF00172.18 EER26667.1 - 0.028 14.5 5.0 0.029 14.5 1.4 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ist1 PF03398.14 EER26668.1 - 5.5e-27 94.7 1.0 4.4e-13 49.5 1.7 2.2 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway HemY_N PF07219.13 EER26669.1 - 0.011 16.0 0.1 0.011 16.0 0.1 3.7 3 1 1 4 4 4 0 HemY protein N-terminus PEX11 PF05648.14 EER26669.1 - 0.073 12.5 0.9 0.11 11.9 0.9 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Clat_adaptor_s PF01217.20 EER26670.1 - 4.1e-54 182.4 1.3 4.8e-54 182.2 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.20 EER26672.1 - 9.3e-25 87.8 0.2 1.7e-24 86.9 0.2 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.16 EER26673.1 - 9.4e-29 99.3 0.4 1e-27 96.0 0.2 2.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Cnd1_N PF12922.7 EER26673.1 - 0.075 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term Aminotran_1_2 PF00155.21 EER26674.1 - 8.8e-64 215.9 0.0 1.1e-63 215.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 EER26674.1 - 0.025 13.5 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Allinase Cys_Met_Meta_PP PF01053.20 EER26674.1 - 0.045 12.3 0.0 0.072 11.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Tam41_Mmp37 PF09139.11 EER26675.1 - 4e-131 437.2 0.0 4.9e-131 437.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial BIR PF00653.21 EER26676.1 - 7.2e-46 154.7 8.2 2.5e-23 82.5 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.8 EER26677.1 - 2.5e-08 34.0 0.4 4.1e-08 33.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER26677.1 - 5.3e-06 26.6 0.5 9.7e-06 25.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EER26677.1 - 0.00094 19.5 0.4 0.0017 18.7 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EER26677.1 - 0.15 12.4 0.3 0.48 10.8 0.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) CBF PF03914.17 EER26677.1 - 1.1 9.3 3.2 0.93 9.5 0.2 2.0 2 0 0 2 2 2 0 CBF/Mak21 family F-box-like PF12937.7 EER26678.1 - 0.00025 20.9 0.0 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EER26678.1 - 0.00077 19.3 0.1 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 F-box domain AMP-binding PF00501.28 EER26679.1 - 1.4e-46 159.0 0.0 2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER26679.1 - 0.00018 22.4 0.0 0.00053 20.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EER26679.1 - 0.0015 18.4 0.0 0.005 16.7 0.0 2.0 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PHB_acc_N PF07879.11 EER26679.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain TetR_C_24 PF17932.1 EER26679.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain adh_short PF00106.25 EER26681.1 - 5.5e-29 101.0 0.8 1.9e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EER26681.1 - 1.1e-22 80.8 0.3 2e-20 73.3 0.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER26681.1 - 1.1e-06 28.7 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EER26681.1 - 0.0043 16.5 0.0 0.0094 15.4 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EER26681.1 - 0.028 13.9 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DSBA PF01323.20 EER26682.1 - 1.4e-14 54.4 0.0 1.6e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain AMP-binding PF00501.28 EER26683.1 - 6.3e-92 308.4 0.1 8e-92 308.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER26683.1 - 7.6e-15 55.7 0.4 1.6e-14 54.6 0.4 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_Rpb5_C PF01191.19 EER26684.1 - 3.7e-33 113.2 0.1 6e-33 112.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EER26684.1 - 1e-26 93.3 0.0 1.6e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EER26684.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Restriction endonuclease EzrA PF06160.12 EER26685.1 - 1.2e-06 27.1 11.4 1.2e-06 27.1 11.4 3.4 2 2 1 3 3 3 2 Septation ring formation regulator, EzrA WEMBL PF05701.11 EER26685.1 - 0.00018 20.4 18.2 0.00018 20.4 18.2 3.1 2 1 1 3 3 3 2 Weak chloroplast movement under blue light APG6_N PF17675.1 EER26685.1 - 0.00036 21.1 5.1 0.00036 21.1 5.1 6.3 2 2 4 6 6 6 1 Apg6 coiled-coil region DUF2968 PF11180.8 EER26685.1 - 0.00038 20.1 9.5 0.00038 20.1 9.5 4.9 3 1 2 5 5 5 2 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.9 EER26685.1 - 0.0034 17.4 13.4 0.0034 17.4 13.4 4.7 2 2 2 4 4 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 EER26685.1 - 0.022 15.5 1.3 0.022 15.5 1.3 4.9 3 2 2 5 5 5 0 Occludin homology domain Golgin_A5 PF09787.9 EER26685.1 - 0.047 13.2 49.7 0.39 10.1 16.5 3.3 2 1 1 3 3 3 0 Golgin subfamily A member 5 DUF2597 PF10772.9 EER26685.1 - 0.093 12.8 0.7 0.27 11.3 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) DUF1664 PF07889.12 EER26685.1 - 0.11 12.5 26.5 0.12 12.5 2.6 4.7 2 2 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4600 PF15372.6 EER26685.1 - 0.84 10.1 38.1 0.36 11.3 5.3 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4600) Fez1 PF06818.15 EER26685.1 - 2.6 8.5 51.3 1.3 9.4 10.5 3.9 2 1 3 5 5 5 0 Fez1 Fib_alpha PF08702.10 EER26685.1 - 3.7 7.7 31.2 0.14 12.4 3.6 4.5 2 1 2 5 5 5 0 Fibrinogen alpha/beta chain family ApoO PF09769.9 EER26685.1 - 3.8 7.5 10.6 18 5.3 0.1 4.4 2 1 2 4 4 4 0 Apolipoprotein O Zw10 PF06248.13 EER26685.1 - 4 5.9 14.1 0.024 13.2 3.9 2.3 2 1 0 2 2 2 0 Centromere/kinetochore Zw10 Baculo_p24 PF05073.12 EER26685.1 - 4.4 7.0 18.1 0.42 10.4 1.0 3.4 3 1 0 3 3 3 0 Baculovirus P24 capsid protein Snapin_Pallidin PF14712.6 EER26685.1 - 4.8 7.7 36.5 2.5 8.6 2.2 6.2 3 1 4 7 7 7 0 Snapin/Pallidin DUF4407 PF14362.6 EER26685.1 - 8.2 5.7 48.5 7.9 5.7 2.6 3.7 2 1 1 3 3 2 0 Domain of unknown function (DUF4407) CYSTM PF12734.7 EER26686.1 - 5.9e-12 45.7 7.2 5.9e-12 45.7 7.2 4.8 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Methyltr_RsmB-F PF01189.17 EER26687.1 - 1.9e-33 115.8 0.0 7.2e-26 91.1 0.0 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Aldolase_II PF00596.21 EER26688.1 - 1.5e-49 168.4 0.2 1.9e-49 168.1 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DEAD PF00270.29 EER26689.1 - 4.5e-43 147.0 0.0 7.8e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26689.1 - 1.2e-20 73.9 0.2 9e-20 71.1 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER26689.1 - 2.2e-05 24.5 0.0 4.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EER26689.1 - 0.0022 17.2 0.1 0.0038 16.5 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ADP_ribosyl_GH PF03747.14 EER26690.1 - 3.2e-64 217.4 0.2 3.7e-64 217.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Ank_2 PF12796.7 EER26691.1 - 9.4e-33 112.7 15.5 2.5e-09 37.6 0.0 13.0 11 2 2 13 13 13 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EER26691.1 - 1.2e-21 74.4 12.8 0.096 13.3 0.0 16.4 18 0 0 18 18 18 5 Ankyrin repeat Ank_4 PF13637.6 EER26691.1 - 1.6e-17 63.6 19.0 0.029 14.9 0.1 13.2 11 3 2 13 13 13 5 Ankyrin repeats (many copies) Ank PF00023.30 EER26691.1 - 3.3e-14 52.6 21.3 1 9.9 0.0 14.7 16 0 0 16 16 16 4 Ankyrin repeat Ank_5 PF13857.6 EER26691.1 - 7e-07 29.4 5.2 0.24 11.8 0.0 8.5 9 1 1 10 10 10 2 Ankyrin repeats (many copies) Adenylsucc_synt PF00709.21 EER26692.1 - 4.1e-169 562.9 0.0 4.7e-169 562.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KHA PF11834.8 EER26692.1 - 0.097 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel DnaJ PF00226.31 EER26693.1 - 6.6e-21 74.2 0.6 1.5e-20 73.1 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 EER26694.1 - 1.3e-25 89.9 0.0 2.7e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26694.1 - 2.3e-08 34.0 10.9 3.9e-08 33.3 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP1_OBG PF01018.22 EER26695.1 - 4.7e-38 130.2 2.9 6.5e-28 97.3 3.4 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EER26695.1 - 3.8e-23 81.8 0.0 6.3e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EER26695.1 - 2e-07 30.7 0.0 3.9e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 EER26695.1 - 0.065 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MeaB PF03308.16 EER26695.1 - 0.14 11.1 0.1 0.78 8.7 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EER26695.1 - 0.23 11.5 0.0 22 5.1 0.1 2.2 1 1 1 2 2 2 0 Dynamin family Arf PF00025.21 EER26695.1 - 0.24 10.8 0.0 0.53 9.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family MFS_1 PF07690.16 EER26696.1 - 1.1e-32 113.4 21.7 4.6e-30 104.7 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER26696.1 - 2.5e-11 43.1 1.4 7.2e-11 41.6 1.4 1.7 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EER26696.1 - 0.0012 17.8 3.5 0.0012 17.8 3.5 2.5 1 1 1 2 2 2 1 MFS_1 like family Cupin_8 PF13621.6 EER26697.1 - 2.4e-32 112.7 0.2 4.1e-32 111.9 0.2 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EER26697.1 - 5.5e-07 29.4 0.0 0.0015 18.1 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 EER26697.1 - 0.011 16.2 0.0 0.065 13.7 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase Homeobox_KN PF05920.11 EER26698.1 - 4.5e-17 61.7 0.4 1e-16 60.5 0.4 1.7 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2 PF00096.26 EER26698.1 - 1.1e-05 25.6 13.4 0.089 13.3 1.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER26698.1 - 9.5e-05 22.9 20.4 0.00077 20.1 1.3 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger Homeodomain PF00046.29 EER26698.1 - 0.00014 21.6 0.1 0.00032 20.5 0.1 1.6 1 0 0 1 1 1 1 Homeodomain HTH_Tnp_Tc5 PF03221.16 EER26698.1 - 0.0037 17.3 0.0 0.013 15.5 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain zf-H2C2_2 PF13465.6 EER26698.1 - 0.043 14.3 6.2 1.2 9.7 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_3rep PF18868.1 EER26698.1 - 0.22 12.2 3.5 0.51 11.0 0.1 2.3 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats UQ_con PF00179.26 EER26699.1 - 1.1e-11 44.5 0.1 2.1e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EER26699.1 - 0.027 14.8 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 RWD domain KAR9 PF08580.10 EER26699.1 - 0.21 10.1 0.5 0.25 9.8 0.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Chorion_2 PF03964.15 EER26699.1 - 0.53 11.2 4.2 12 6.7 0.0 3.0 2 1 0 2 2 2 0 Chorion family 2 2OG-FeII_Oxy_2 PF13532.6 EER26701.1 - 7.8e-37 127.4 0.2 1e-36 127.0 0.2 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EER26701.1 - 5e-08 32.9 8.3 1.2e-07 31.6 8.3 1.7 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.16 EER26701.1 - 0.024 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 CUE domain Abhydrolase_6 PF12697.7 EER26702.1 - 1e-12 49.1 6.8 4.8e-12 47.0 6.8 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER26702.1 - 1.1e-05 25.2 0.1 2.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER26702.1 - 0.0044 16.3 0.1 0.37 10.0 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF3089 PF11288.8 EER26702.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) WD40 PF00400.32 EER26703.1 - 2.7e-15 56.5 18.7 0.016 16.1 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER26703.1 - 0.12 12.7 0.0 6.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ccdc124 PF06244.12 EER26704.1 - 1.2e-27 97.0 17.1 1.2e-27 97.0 17.1 2.2 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF5539 PF17693.1 EER26704.1 - 0.0022 17.7 3.9 0.0028 17.4 3.9 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5539) F-box PF00646.33 EER26705.1 - 1e-06 28.5 0.1 2.8e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EER26705.1 - 1.5e-06 27.9 0.0 4.3e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EER26705.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 F-box CENP-B_dimeris PF09026.10 EER26705.1 - 0.14 12.6 2.2 0.68 10.4 2.2 2.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_C13 PF01650.18 EER26706.1 - 1e-40 139.9 0.0 1.5e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family CDC45 PF02724.14 EER26707.1 - 1.1e-243 810.2 0.0 3.4e-243 808.6 0.0 2.3 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 EER26707.1 - 0.0051 16.6 5.9 0.0051 16.6 5.9 2.9 3 0 0 3 3 3 1 Cwf15/Cwc15 cell cycle control protein TAF4 PF05236.14 EER26707.1 - 0.81 9.4 11.0 0.85 9.3 3.1 2.4 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family CPSF100_C PF13299.6 EER26707.1 - 5.4 7.2 6.0 15 5.8 1.2 3.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DDRGK PF09756.9 EER26707.1 - 6.6 6.3 13.5 15 5.1 13.5 1.5 1 0 0 1 1 1 0 DDRGK domain BUD22 PF09073.10 EER26707.1 - 6.8 5.9 34.4 0.29 10.4 10.0 2.8 3 0 0 3 3 3 0 BUD22 Nop14 PF04147.12 EER26707.1 - 9.2 4.3 23.2 0.41 8.8 6.4 2.2 2 0 0 2 2 2 0 Nop14-like family DUF1330 PF07045.11 EER26708.1 - 0.036 14.4 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) ERAP1_C PF11838.8 EER26708.1 - 0.038 13.5 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Acetyltransf_7 PF13508.7 EER26709.1 - 1.5e-09 38.1 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER26709.1 - 2.2e-09 37.6 0.0 3.5e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER26709.1 - 3.3e-08 33.5 0.0 5.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER26709.1 - 0.00049 20.2 0.0 0.0012 18.9 0.0 1.8 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EER26709.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 EER26709.1 - 0.021 14.9 0.0 1.4 9.0 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EER26710.1 - 6.6e-19 69.0 0.0 9e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER26710.1 - 4.5e-05 23.7 0.0 6.2e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EER26710.1 - 0.00077 19.2 0.1 0.0033 17.1 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER26710.1 - 0.034 14.1 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 EER26710.1 - 0.036 14.2 0.0 0.056 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Zn_clus PF00172.18 EER26711.1 - 0.00024 21.2 8.2 0.00045 20.3 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.20 EER26712.1 - 3e-143 478.0 0.0 3.4e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Histidinol_dh PF00815.20 EER26713.1 - 2e-161 537.6 4.3 2.6e-161 537.2 4.3 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 EER26713.1 - 5.2e-24 83.9 0.1 1e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EER26713.1 - 1.2e-13 51.3 0.1 3.3e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Metallophos_2 PF12850.7 EER26713.1 - 0.062 13.5 0.2 0.5 10.5 0.2 2.1 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Utp11 PF03998.13 EER26714.1 - 6.3e-24 85.3 14.9 7.2e-24 85.1 14.9 1.0 1 0 0 1 1 1 1 Utp11 protein PRKCSH-like PF12999.7 EER26714.1 - 0.32 10.8 3.2 0.52 10.1 3.2 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like RR_TM4-6 PF06459.12 EER26714.1 - 6.1 6.6 10.9 8.6 6.1 10.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cmc1 PF08583.10 EER26715.1 - 1.7e-14 53.5 4.2 1.7e-14 53.5 4.2 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 EER26715.1 - 0.0036 17.0 1.5 0.006 16.3 1.5 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 EER26715.1 - 0.053 13.5 0.1 0.089 12.8 0.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TFIID-31kDa PF02291.15 EER26716.1 - 8.9e-45 151.7 0.0 1.2e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit DUF4106 PF13388.6 EER26716.1 - 0.14 11.3 1.0 0.19 10.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) SDA1 PF05285.12 EER26717.1 - 1.9e-96 323.6 34.5 1.9e-96 323.6 34.5 2.4 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 EER26717.1 - 9.2e-24 83.5 0.1 2.6e-23 82.1 0.1 1.9 1 0 0 1 1 1 1 NUC130/3NT domain Ribosomal_S7 PF00177.21 EER26718.1 - 5.8e-37 126.6 2.7 7.5e-37 126.3 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Metallophos PF00149.28 EER26719.1 - 2.3e-10 41.3 1.2 3.5e-10 40.7 1.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EER26719.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Pectate_lyase_3 PF12708.7 EER26719.1 - 0.11 12.4 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 Pectate lyase superfamily protein AMP-binding PF00501.28 EER26720.1 - 9.2e-65 218.9 0.1 3.1e-24 85.4 0.1 4.4 3 1 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.11 EER26720.1 - 4.7e-10 40.3 0.1 1.2e-09 38.9 0.1 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 EER26720.1 - 0.0043 17.0 1.6 0.011 15.8 1.6 1.7 1 0 0 1 1 1 1 Gas vesicle protein G HMGL-like PF00682.19 EER26721.1 - 2.9e-81 272.9 0.0 6e-81 271.9 0.0 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 EER26721.1 - 8.3e-24 84.0 0.1 2.4e-23 82.5 0.1 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain DEAD PF00270.29 EER26722.1 - 5.9e-48 162.9 0.1 1.6e-47 161.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26722.1 - 1.3e-28 99.6 0.1 1.6e-26 92.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EER26722.1 - 0.0035 16.2 0.4 0.077 11.8 0.0 2.8 3 1 1 4 4 4 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Acetyltransf_1 PF00583.25 EER26724.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family PapD_N PF00345.20 EER26724.1 - 0.016 15.1 0.0 0.063 13.2 0.0 2.1 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF4045 PF13254.6 EER26725.1 - 2.1e-117 393.3 35.6 2.1e-117 393.3 35.6 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EER26725.1 - 1.6e-08 34.3 0.3 0.06 13.2 0.1 3.7 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.14 EER26726.1 - 6.8e-91 304.7 0.0 1e-90 304.1 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EER26726.1 - 3.3e-30 104.6 0.0 5.2e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.18 EER26727.1 - 4e-09 36.4 12.1 9.1e-09 35.3 12.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 EER26728.1 - 3e-23 82.3 0.0 3.5e-19 69.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EER26728.1 - 2.4e-13 50.2 0.0 1.4e-10 41.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER26728.1 - 1.2e-09 38.4 0.1 2e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 KR domain PAPS_reduct PF01507.19 EER26728.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family PLDc_N PF13396.6 EER26728.1 - 0.23 11.4 2.1 0.5 10.4 2.1 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Zn_clus PF00172.18 EER26729.1 - 3.1e-08 33.6 11.5 3.1e-08 33.6 11.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EER26729.1 - 5.8e-05 22.2 0.1 0.0001 21.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GLYCAM-1 PF05242.11 EER26729.1 - 0.11 12.6 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DnaJ PF00226.31 EER26730.1 - 8.5e-17 61.0 1.0 2.2e-16 59.7 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EER26730.1 - 3.3e-10 39.6 0.0 5.3e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DTHCT PF08070.11 EER26730.1 - 7.9 7.3 11.3 8.8 7.1 0.5 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region Pkinase_Tyr PF07714.17 EER26731.1 - 7.8e-05 22.1 0.1 0.0012 18.2 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EER26731.1 - 0.0012 18.2 0.0 0.015 14.6 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EER26732.1 - 1.1e-24 86.7 2.4 1e-05 26.0 0.2 5.2 3 1 1 5 5 5 4 Ankyrin repeats (3 copies) Pkinase PF00069.25 EER26732.1 - 1e-23 84.1 0.0 1.6e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.6 EER26732.1 - 1.5e-21 76.2 9.9 1.1e-06 28.8 0.1 6.2 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EER26732.1 - 2.1e-21 76.0 9.7 6.8e-05 23.3 0.1 7.9 5 3 5 10 10 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EER26732.1 - 2.3e-17 62.6 11.8 3.3e-05 24.1 0.7 7.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 EER26732.1 - 6.8e-16 56.8 8.4 0.00079 19.7 0.1 8.2 8 0 0 8 8 8 3 Ankyrin repeat Pkinase_Tyr PF07714.17 EER26732.1 - 2.1e-13 50.2 0.0 3.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_10 PF13374.6 EER26732.1 - 1.3e-06 28.1 0.0 5.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EER26732.1 - 0.00069 19.9 0.0 0.01 16.1 0.0 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat Kdo PF06293.14 EER26732.1 - 0.075 12.4 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EER26732.1 - 0.19 10.7 0.0 0.31 10.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3480 PF11979.8 EER26733.1 - 0.067 12.1 0.0 0.57 9.1 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3480) Peptidase_M24 PF00557.24 EER26734.1 - 5e-57 193.0 0.0 6.9e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EER26734.1 - 1.9e-23 82.5 0.0 3.5e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SPRY PF00622.28 EER26735.1 - 1.4e-19 70.3 0.1 2.4e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain PDEase_II PF02112.15 EER26736.1 - 4.8e-53 180.4 0.0 2.5e-45 155.1 0.0 2.7 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EER26736.1 - 0.016 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EER26736.1 - 0.018 15.0 0.1 0.041 13.9 0.1 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Amidase PF01425.21 EER26737.1 - 3.1e-76 257.2 0.5 1.3e-75 255.1 0.5 1.8 1 1 0 1 1 1 1 Amidase GWT1 PF06423.12 EER26738.1 - 2.6e-40 138.0 2.0 2.6e-40 138.0 2.0 1.9 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 EER26738.1 - 0.0018 18.8 0.1 0.053 14.0 0.0 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4818) Acyl-CoA_dh_1 PF00441.24 EER26739.1 - 2.5e-38 131.6 6.9 4e-38 131.0 6.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EER26739.1 - 2.4e-30 105.5 0.8 4.6e-30 104.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EER26739.1 - 1.5e-24 86.0 0.0 3.4e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EER26739.1 - 8.4e-16 58.5 3.2 1.6e-15 57.6 3.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EER26739.1 - 0.015 15.0 0.0 0.044 13.4 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal AgrD PF05931.11 EER26739.1 - 0.028 14.4 0.0 0.09 12.8 0.0 1.8 1 0 0 1 1 1 0 Staphylococcal AgrD protein Senescence PF06911.12 EER26740.1 - 1.2e-55 188.7 5.4 1.8e-55 188.1 5.4 1.3 1 0 0 1 1 1 1 Senescence-associated protein Pkinase PF00069.25 EER26741.1 - 1.8e-63 214.4 0.0 3.4e-63 213.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER26741.1 - 6.2e-35 120.7 0.0 1.8e-29 102.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EER26741.1 - 4.4e-07 29.5 0.0 0.00055 19.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EER26741.1 - 7.6e-05 22.7 0.2 0.00067 19.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EER26741.1 - 0.013 15.1 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 EER26741.1 - 0.018 14.0 0.1 0.035 13.1 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EER26741.1 - 0.098 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MMM1 PF10296.9 EER26742.1 - 2.5e-06 26.8 0.0 6.3e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 Bap31 PF05529.12 EER26743.1 - 2.1e-49 166.9 6.2 2.6e-49 166.5 6.2 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EER26743.1 - 2.2e-14 53.2 4.5 2.2e-14 53.2 4.5 1.6 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EER26743.1 - 0.0029 17.4 2.5 0.012 15.3 0.3 2.8 3 0 0 3 3 3 1 Septum formation initiator TMF_DNA_bd PF12329.8 EER26743.1 - 0.012 15.6 0.7 0.012 15.6 0.7 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4349 PF14257.6 EER26743.1 - 0.028 13.9 0.8 0.057 12.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Phage_GP20 PF06810.11 EER26743.1 - 0.077 12.8 2.0 0.079 12.8 0.5 1.6 2 0 0 2 2 2 0 Phage minor structural protein GP20 GPS2_interact PF15784.5 EER26743.1 - 0.25 11.8 2.7 0.24 11.9 0.8 1.8 1 1 1 2 2 2 0 G-protein pathway suppressor 2-interacting domain Dus PF01207.17 EER26745.1 - 1.3e-43 149.3 0.0 7.7e-31 107.3 0.0 2.9 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 EER26745.1 - 0.00056 19.6 2.0 0.00056 19.6 2.0 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EER26745.1 - 0.0091 16.0 0.7 0.0091 16.0 0.7 2.4 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 EER26745.1 - 0.0092 15.9 0.3 0.03 14.2 0.3 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tyr-DNA_phospho PF06087.12 EER26745.1 - 0.085 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Kelch_4 PF13418.6 EER26746.1 - 5.1e-23 80.8 11.6 3.4e-07 30.2 0.0 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EER26746.1 - 1.3e-22 78.8 3.1 1.4e-05 24.9 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_5 PF13854.6 EER26746.1 - 2.2e-22 78.6 1.9 7e-05 22.7 0.0 4.7 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EER26746.1 - 3.3e-21 74.8 6.0 0.00022 21.4 0.0 4.8 3 1 2 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EER26746.1 - 2.5e-17 62.7 10.2 9.9e-07 28.9 0.3 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EER26746.1 - 2.1e-16 59.2 4.7 0.00067 19.2 0.2 4.6 4 0 0 4 4 4 3 Kelch motif BTB PF00651.31 EER26746.1 - 3.6e-11 43.3 0.0 7.2e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 EER26747.1 - 9.9e-16 57.8 4.0 5.4e-06 26.6 0.2 4.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EER26747.1 - 3.6e-15 56.1 17.9 0.00044 21.0 0.1 6.5 6 1 1 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EER26747.1 - 7.4e-06 25.1 0.0 0.00086 18.3 0.0 3.2 2 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EER26747.1 - 0.00012 22.1 0.4 0.031 14.2 0.1 2.5 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A DUF4778 PF16008.5 EER26747.1 - 0.047 13.7 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) TFIIA PF03153.13 EER26748.1 - 1.3e-83 282.4 0.6 1.5e-83 282.2 0.6 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit UPF0184 PF03670.13 EER26748.1 - 3.6 8.0 5.9 2.6 8.5 1.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) zf-C2H2 PF00096.26 EER26749.1 - 1.1e-05 25.6 9.9 0.068 13.7 0.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER26749.1 - 0.00018 22.0 11.1 0.027 15.3 0.7 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EER26749.1 - 0.0013 18.9 2.8 0.18 11.9 0.1 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger DUF4719 PF15843.5 EER26749.1 - 0.018 15.1 0.8 0.067 13.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) zf-H2C2_2 PF13465.6 EER26749.1 - 0.024 15.1 0.5 0.024 15.1 0.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EER26749.1 - 0.063 13.6 2.6 2 8.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EER26749.1 - 8.3 6.5 9.5 0.53 10.3 1.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger FlxA PF14282.6 EER26750.1 - 0.0021 18.0 1.7 0.0021 18.0 1.7 2.4 2 0 0 2 2 2 1 FlxA-like protein Mei5 PF10376.9 EER26750.1 - 0.0048 16.8 7.7 0.014 15.3 4.9 2.7 2 1 0 2 2 2 1 Double-strand recombination repair protein DUF4094 PF13334.6 EER26750.1 - 0.013 15.9 0.8 0.024 15.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) TFIIA PF03153.13 EER26750.1 - 0.026 14.5 11.1 0.032 14.2 11.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LPP PF04728.13 EER26750.1 - 0.17 12.3 1.1 0.44 11.0 1.1 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DASH_Hsk3 PF08227.11 EER26750.1 - 0.22 11.9 3.1 0.41 11.0 3.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Hsk3 like ATG16 PF08614.11 EER26750.1 - 0.32 11.2 8.0 0.24 11.6 3.8 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) AATF-Che1 PF13339.6 EER26750.1 - 0.95 10.1 5.8 1.8 9.2 5.6 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4407 PF14362.6 EER26750.1 - 9.5 5.5 10.2 18 4.5 10.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Sel1 PF08238.12 EER26751.1 - 1.4e-30 105.0 32.8 5.5e-05 23.7 0.1 11.6 11 1 0 11 11 11 7 Sel1 repeat DUF1771 PF08590.10 EER26751.1 - 0.0038 17.6 3.3 0.0078 16.6 0.8 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) DUF4419 PF14388.6 EER26751.1 - 0.017 14.5 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) VGCC_beta4Aa_N PF12052.8 EER26751.1 - 0.041 14.0 0.5 0.12 12.5 0.5 1.8 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Host_attach PF10116.9 EER26751.1 - 0.094 13.3 0.3 5.2 7.7 0.0 2.9 3 0 0 3 3 3 0 Protein required for attachment to host cells TPR_19 PF14559.6 EER26751.1 - 0.44 11.1 7.4 2.7 8.6 0.2 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Aldedh PF00171.22 EER26752.1 - 8.5e-142 472.9 0.0 1e-141 472.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EER26752.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) WD40 PF00400.32 EER26753.1 - 7.1e-17 61.5 2.1 1.2e-05 25.9 0.2 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER26753.1 - 0.0014 18.9 0.0 10 6.5 0.0 3.6 3 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 EER26754.1 - 1.5e-13 50.9 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER26754.1 - 1.7e-08 35.1 0.0 1.6e-06 28.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER26754.1 - 3.7e-06 26.8 0.0 1.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER26754.1 - 3.3e-05 24.4 0.0 0.0033 18.0 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EER26754.1 - 7.3e-05 22.3 0.0 0.00056 19.4 0.0 2.3 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_12 PF08242.12 EER26754.1 - 0.00013 22.7 0.0 0.0073 17.0 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 EER26754.1 - 0.00059 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EER26754.1 - 0.0022 18.1 0.0 0.0043 17.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EER26754.1 - 0.0058 16.0 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EER26754.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 EER26754.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 EER26754.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 EER26754.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) WD40 PF00400.32 EER26755.1 - 8.3e-15 54.9 10.1 2.3e-05 25.1 0.5 5.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER26755.1 - 5.6e-11 42.6 0.3 0.0022 18.3 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER26755.1 - 0.00066 19.6 0.1 3 7.7 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RNA_pol_Rpb1_1 PF04997.12 EER26756.1 - 6.1e-112 374.0 0.0 9.9e-112 373.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EER26756.1 - 9.4e-104 346.6 0.1 1.4e-103 345.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EER26756.1 - 1.5e-75 253.0 0.0 3.1e-75 252.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EER26756.1 - 1e-66 224.5 1.6 2e-66 223.5 1.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EER26756.1 - 3.4e-47 160.3 0.0 7.7e-47 159.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EER26756.1 - 4.7e-46 156.1 6.8 1e-45 155.1 6.8 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EER26756.1 - 3.2e-37 126.8 0.1 6.9e-37 125.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EER26756.1 - 1.7e-20 72.2 197.7 0.0037 17.5 0.8 14.0 12 1 1 13 13 13 12 RNA polymerase Rpb1 C-terminal repeat LNS2 PF08235.13 EER26757.1 - 8.5e-96 319.8 0.0 1.2e-95 319.3 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EER26757.1 - 5.2e-43 145.2 0.0 9.3e-43 144.4 0.0 1.4 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EER26757.1 - 0.0051 16.4 0.0 0.076 12.6 0.0 2.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.21 EER26758.1 - 9.3e-05 22.7 0.0 0.00032 21.0 0.0 2.0 1 0 0 1 1 1 1 Fibronectin type III domain APG6_N PF17675.1 EER26758.1 - 6.2 7.4 50.4 4.1 7.9 19.8 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region Thg1C PF14413.6 EER26759.1 - 4.3e-52 175.4 0.5 5.7e-52 175.0 0.5 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.12 EER26759.1 - 2.3e-15 56.7 0.1 4.5e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase RNR_inhib PF08591.10 EER26761.1 - 1.5e-20 74.5 0.7 4.1e-20 73.1 0.0 2.1 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor AA_permease PF00324.21 EER26762.1 - 1.7e-54 185.2 31.5 1.6e-52 178.7 26.4 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 EER26762.1 - 2.7e-17 62.7 26.3 4.4e-17 62.0 26.0 1.4 1 1 0 1 1 1 1 Amino acid permease HSP70 PF00012.20 EER26763.1 - 2.3e-59 201.2 0.7 1.4e-56 192.0 0.5 3.4 3 0 0 3 3 3 2 Hsp70 protein CCDC24 PF15669.5 EER26763.1 - 0.49 10.2 12.6 0.57 10.0 1.2 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 24 family APH PF01636.23 EER26764.1 - 0.0031 17.5 0.3 0.0061 16.5 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Tubulin_3 PF14881.6 EER26766.1 - 5.5e-84 280.3 0.0 1.1e-83 279.3 0.0 1.5 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 EER26766.1 - 2.5e-42 143.9 0.0 5e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EER26766.1 - 3.6e-06 27.3 0.0 0.0064 16.7 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain HR1 PF02185.16 EER26767.1 - 0.57 10.3 0.1 0.57 10.3 0.1 4.6 3 1 2 5 5 5 0 Hr1 repeat Laminin_II PF06009.12 EER26767.1 - 5.2 7.1 11.1 31 4.6 6.0 2.5 1 1 1 2 2 2 0 Laminin Domain II DUF2347 PF09804.9 EER26768.1 - 3.1e-104 348.5 0.0 4.1e-104 348.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EER26768.1 - 2.8e-61 207.2 0.1 4.4e-61 206.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 EER26768.1 - 5.9e-05 21.9 0.1 1 8.0 0.0 3.6 3 1 1 4 4 4 2 Transport protein Avl9 EBP PF05241.12 EER26769.1 - 1.8e-58 196.9 9.6 2.2e-58 196.7 9.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein SNF2_N PF00176.23 EER26771.1 - 2.9e-63 213.7 0.0 4.7e-63 213.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER26771.1 - 4.2e-14 52.8 0.0 9e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER26771.1 - 7.8e-10 39.0 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EER26771.1 - 0.015 15.0 0.0 0.035 13.8 0.0 1.6 2 0 0 2 2 2 0 SWI2/SNF2 ATPase HDA2-3 PF11496.8 EER26771.1 - 0.018 14.2 0.0 0.043 13.0 0.0 1.6 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 RPN13_C PF16550.5 EER26771.1 - 0.1 12.8 0.2 1 9.6 0.0 2.4 1 1 1 2 2 2 0 UCH-binding domain AAA_2 PF07724.14 EER26772.1 - 4.4e-46 157.1 0.0 6.2e-45 153.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EER26772.1 - 4.4e-33 113.3 3.2 4.4e-33 113.3 3.2 3.4 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 EER26772.1 - 2.3e-26 92.8 0.1 5.9e-14 52.6 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EER26772.1 - 3e-24 84.9 0.6 3e-24 84.9 0.6 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EER26772.1 - 8.7e-16 58.2 0.0 1.6e-09 37.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EER26772.1 - 2.3e-14 54.2 3.6 9.6e-07 29.3 0.0 5.4 3 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 EER26772.1 - 1.1e-13 51.6 0.1 4.4e-05 23.8 0.0 4.6 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EER26772.1 - 6.8e-09 35.6 0.0 1.5e-05 24.8 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 EER26772.1 - 4.9e-07 29.8 3.3 0.00012 22.2 0.0 4.1 4 0 0 4 4 3 1 Clp amino terminal domain, pathogenicity island component AAA_7 PF12775.7 EER26772.1 - 1.9e-06 27.6 0.0 0.015 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EER26772.1 - 2.1e-06 27.6 0.0 0.097 12.4 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 EER26772.1 - 5.5e-06 26.4 0.0 0.22 11.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EER26772.1 - 7.9e-06 25.4 0.1 0.17 11.3 0.1 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EER26772.1 - 1.4e-05 25.3 0.2 0.25 11.5 0.0 3.6 3 1 0 3 3 2 2 AAA domain TniB PF05621.11 EER26772.1 - 1.8e-05 24.2 0.1 0.21 11.0 0.0 4.3 3 2 0 3 3 3 1 Bacterial TniB protein ATPase_2 PF01637.18 EER26772.1 - 2.7e-05 24.2 3.4 0.11 12.4 0.3 4.2 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EER26772.1 - 6.2e-05 23.6 3.6 0.14 12.7 0.0 3.6 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.22 EER26772.1 - 8e-05 23.0 0.0 0.55 10.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_23 PF13476.6 EER26772.1 - 8.2e-05 23.2 5.8 0.38 11.2 0.0 3.9 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 EER26772.1 - 0.00011 22.0 0.0 1 9.0 0.0 3.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EER26772.1 - 0.00011 22.7 1.2 1 9.9 0.0 3.6 3 0 0 3 3 3 1 ABC transporter TsaE PF02367.17 EER26772.1 - 0.00023 21.2 0.0 0.28 11.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EER26772.1 - 0.00045 20.5 5.3 0.56 10.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_3 PF07726.11 EER26772.1 - 0.00046 20.1 0.0 1.6 8.6 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EER26772.1 - 0.0005 19.9 0.9 4.6 7.0 0.5 4.3 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EER26772.1 - 0.00051 20.0 0.0 0.69 9.8 0.0 3.0 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 EER26772.1 - 0.00052 19.1 0.1 0.004 16.2 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.6 EER26772.1 - 0.00061 19.6 0.1 0.86 9.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EER26772.1 - 0.00094 18.9 0.1 1.2 9.0 0.0 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EER26772.1 - 0.0017 18.7 1.1 0.42 10.9 0.2 3.4 3 1 1 4 4 3 1 AAA domain Roc PF08477.13 EER26772.1 - 0.0035 17.5 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 EER26772.1 - 0.0049 17.0 0.0 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 Torsin NACHT PF05729.12 EER26772.1 - 0.0051 16.7 0.0 0.4 10.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain ResIII PF04851.15 EER26772.1 - 0.0054 16.8 0.0 1.4 8.9 0.0 3.6 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EER26772.1 - 0.0081 16.1 0.0 0.17 11.8 0.0 2.7 2 0 0 2 2 2 1 NTPase Zeta_toxin PF06414.12 EER26772.1 - 0.012 14.9 0.0 1.4 8.2 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 EER26772.1 - 0.031 14.2 0.0 7.3 6.5 0.0 2.9 2 1 0 2 2 2 0 Rad17 P-loop domain SRP54 PF00448.22 EER26772.1 - 0.048 13.3 1.2 7.1 6.2 0.0 3.2 4 0 0 4 4 2 0 SRP54-type protein, GTPase domain GAS PF13851.6 EER26772.1 - 0.049 13.0 8.1 0.11 11.8 8.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Rossmann-like PF10727.9 EER26772.1 - 0.088 12.7 4.2 7 6.5 0.1 3.5 3 0 0 3 3 3 0 Rossmann-like domain CbiA PF01656.23 EER26772.1 - 0.11 12.5 0.0 17 5.5 0.0 3.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MPS2 PF17060.5 EER26772.1 - 0.16 11.2 3.1 0.29 10.4 3.1 1.4 1 0 0 1 1 1 0 Monopolar spindle protein 2 V_ATPase_I PF01496.19 EER26772.1 - 0.19 9.6 2.5 0.28 9.1 2.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_25 PF13481.6 EER26772.1 - 0.2 11.2 6.9 0.55 9.8 0.0 3.4 4 0 0 4 4 3 0 AAA domain Macoilin PF09726.9 EER26772.1 - 0.6 8.6 9.4 0.9 8.0 9.4 1.2 1 0 0 1 1 1 0 Macoilin family Sulfotransfer_3 PF13469.6 EER26773.1 - 0.02 15.3 0.0 8.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Sulfotransferase family Collagen PF01391.18 EER26773.1 - 0.64 9.8 7.2 2.4 8.0 0.4 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Prefoldin_2 PF01920.20 EER26774.1 - 1.5e-24 86.0 3.0 1.9e-24 85.7 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EER26774.1 - 0.007 16.3 3.4 0.16 11.9 0.1 2.2 1 1 1 2 2 2 1 Prefoldin subunit Mei5 PF10376.9 EER26774.1 - 0.0077 16.1 4.5 0.0095 15.8 4.5 1.1 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF1664 PF07889.12 EER26774.1 - 0.076 13.1 2.2 2 8.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EER26774.1 - 0.1 12.7 0.9 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus VPS38 PF17649.1 EER26774.1 - 0.14 11.0 2.2 0.2 10.5 2.2 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 Spc24 PF08286.11 EER26774.1 - 0.18 12.1 6.5 3 8.1 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 GPS2_interact PF15784.5 EER26774.1 - 0.24 11.8 7.7 0.33 11.4 0.1 2.3 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Seryl_tRNA_N PF02403.22 EER26774.1 - 0.38 11.0 8.9 2.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 EER26774.1 - 0.41 11.1 2.5 9.9 6.7 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 EER26774.1 - 0.42 11.0 0.2 0.42 11.0 0.2 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Spc19 PF08287.11 EER26774.1 - 0.68 9.8 10.5 2.1 8.2 0.1 2.2 2 0 0 2 2 2 0 Spc19 APG6_N PF17675.1 EER26774.1 - 0.75 10.3 17.4 5.6 7.5 0.3 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 EER26774.1 - 0.96 9.5 11.7 7.2 6.7 8.4 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EER26774.1 - 2.1 8.2 11.1 4.3 7.2 5.3 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 EER26774.1 - 3.2 8.2 7.9 4.4 7.8 0.1 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ATG27 PF09451.10 EER26775.1 - 4e-100 335.0 0.0 4.9e-100 334.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EER26775.1 - 1.8e-07 31.4 0.0 1e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat DUF3140 PF11338.8 EER26775.1 - 0.19 12.2 2.7 0.36 11.3 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) I-EGF_1 PF18372.1 EER26775.1 - 0.27 11.4 1.0 0.51 10.5 1.0 1.4 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 Fungal_trans PF04082.18 EER26776.1 - 5.1e-21 74.9 0.2 8.9e-21 74.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26776.1 - 7e-06 26.1 12.8 1.6e-05 25.0 12.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EBP50_C PF09007.11 EER26776.1 - 8.7 7.3 9.2 0.42 11.6 0.9 2.4 2 0 0 2 2 2 0 EBP50, C-terminal PAC4 PF16093.5 EER26777.1 - 1.1e-25 89.6 0.6 1.8e-25 88.9 0.6 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 N2227 PF07942.12 EER26778.1 - 2.1e-91 305.9 0.0 2.5e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EER26778.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Chlamy_scaf PF09675.10 EER26778.1 - 0.067 13.5 0.2 7.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) Methyltransf_11 PF08241.12 EER26778.1 - 0.18 12.5 0.0 0.75 10.5 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain HSP70 PF00012.20 EER26779.1 - 4.8e-10 38.3 0.2 5.6e-09 34.7 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EER26779.1 - 0.14 10.9 0.0 0.5 9.1 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Chorismate_bind PF00425.18 EER26780.1 - 6.7e-85 284.8 0.0 9.1e-85 284.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EER26780.1 - 6.7e-36 123.9 0.0 1.1e-35 123.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EER26780.1 - 1.2e-08 35.2 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EER26780.1 - 0.00028 20.7 1.1 0.0021 17.9 1.1 2.2 1 1 0 1 1 1 1 Peptidase C26 PsiA PF06952.11 EER26780.1 - 0.0045 16.3 0.1 0.0077 15.5 0.1 1.3 1 0 0 1 1 1 1 PsiA protein DUF3445 PF11927.8 EER26781.1 - 9.7e-62 208.5 0.1 1.2e-61 208.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) 4HBT_3 PF13622.6 EER26782.1 - 3.1e-78 263.4 0.2 3.8e-78 263.2 0.2 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EER26782.1 - 9.1e-23 80.5 0.0 2.6e-11 43.5 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase PAP_central PF04928.17 EER26783.1 - 6e-109 362.8 0.0 7.7e-109 362.4 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EER26783.1 - 4.4e-59 199.0 0.0 6.6e-59 198.4 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EER26783.1 - 9.2e-11 41.9 0.0 2.1e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_1 PF00561.20 EER26784.1 - 1.9e-15 57.2 0.0 1.4e-11 44.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER26784.1 - 0.00056 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EER26784.1 - 0.0037 17.9 0.1 0.005 17.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Muraidase PF11860.8 EER26784.1 - 0.006 16.8 0.0 0.023 14.9 0.0 1.9 1 1 0 1 1 1 1 N-acetylmuramidase Esterase PF00756.20 EER26784.1 - 0.064 12.9 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.18 EER26785.1 - 1.8e-17 63.3 0.0 1.8e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26785.1 - 2.4e-07 30.8 7.9 4.2e-07 30.0 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1647 PF07801.11 EER26785.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) But2 PF09792.9 EER26787.1 - 0.00028 21.3 0.0 0.00062 20.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Mito_carr PF00153.27 EER26788.1 - 1.3e-43 146.8 6.5 2.9e-16 59.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UBA_4 PF14555.6 EER26789.1 - 1.2e-11 44.2 0.0 4e-11 42.6 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 EER26789.1 - 5.4e-09 36.1 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF572 PF04502.13 EER26789.1 - 0.27 10.8 4.8 0.38 10.3 4.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DDRGK PF09756.9 EER26789.1 - 1.1 8.8 15.0 1.8 8.1 15.0 1.2 1 0 0 1 1 1 0 DDRGK domain PALP PF00291.25 EER26790.1 - 3.5e-54 184.2 0.0 4.8e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LSM PF01423.22 EER26791.1 - 8.9e-21 73.4 0.2 1.1e-20 73.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 EER26791.1 - 0.00086 19.8 13.2 0.0016 19.0 13.2 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 EER26791.1 - 0.0025 17.9 0.1 0.0043 17.1 0.1 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain SM-ATX PF14438.6 EER26791.1 - 0.16 12.2 0.1 0.3 11.2 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Zn_clus PF00172.18 EER26792.1 - 0.022 14.9 8.8 0.04 14.0 8.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TT_ORF2 PF02957.15 EER26792.1 - 2.1 9.3 6.8 14 6.6 0.2 2.5 2 0 0 2 2 2 0 TT viral ORF2 Dioxygenase_C PF00775.21 EER26793.1 - 3.8e-42 143.8 0.0 5.6e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EER26793.1 - 1.3e-31 108.2 0.0 2.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EER26793.1 - 0.002 18.4 0.1 0.0081 16.4 0.1 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain TTR-52 PF01060.23 EER26793.1 - 0.0068 17.1 0.0 0.017 15.8 0.0 1.6 1 0 0 1 1 1 1 Transthyretin-like family Big_1 PF02369.16 EER26793.1 - 0.031 14.3 0.2 0.077 13.0 0.2 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) MetallophosN PF16371.5 EER26793.1 - 0.035 14.4 0.2 1.6 9.0 0.2 2.4 1 1 1 2 2 2 0 N terminal of Calcineurin-like phosphoesterase DUF4198 PF10670.9 EER26793.1 - 0.067 13.5 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Vps39_2 PF10367.9 EER26794.1 - 1.3e-05 25.6 0.0 5.2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EER26794.1 - 0.0084 16.4 0.0 0.5 10.7 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 EER26794.1 - 0.1 12.5 0.0 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS CASP_C PF08172.12 EER26795.1 - 1.6e-91 306.1 1.9 1.6e-91 306.1 1.9 3.6 3 1 1 4 4 4 1 CASP C terminal T3SS_needle_F PF09392.10 EER26795.1 - 0.3 11.3 2.2 4.5 7.5 0.0 3.7 3 0 0 3 3 3 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF NAD_binding_1 PF00175.21 EER26795.1 - 1.7 9.3 3.6 12 6.5 0.0 3.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain APG6_N PF17675.1 EER26795.1 - 4.1 8.0 72.7 0.23 12.0 7.6 5.7 2 1 3 6 6 6 0 Apg6 coiled-coil region Ribosomal_L22 PF00237.19 EER26796.1 - 2.8e-41 139.9 0.1 4.2e-41 139.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1609 PF07753.11 EER26796.1 - 0.14 11.6 0.0 4 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1609) 2-Hacid_dh_C PF02826.19 EER26797.1 - 5.5e-55 185.5 0.0 7.1e-55 185.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER26797.1 - 4.6e-17 61.9 0.0 5.3e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EER26797.1 - 0.11 12.7 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 EER26798.1 - 3.1e-26 91.4 0.1 5.2e-26 90.7 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER26798.1 - 5.1e-11 42.7 0.0 1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EER26798.1 - 9.1e-11 41.6 0.0 6.3e-05 22.6 0.0 2.2 1 1 0 2 2 2 2 Glucose dehydrogenase C-terminus Sacchrp_dh_NADP PF03435.18 EER26798.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ADH_zinc_N_2 PF13602.6 EER26798.1 - 0.011 16.8 0.0 0.021 15.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EER26798.1 - 0.072 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EER26798.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EER26798.1 - 0.081 13.5 0.5 17 6.1 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 EER26799.1 - 1.2e-46 159.2 1.9 1.4e-46 159.0 1.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER26799.1 - 1.5e-44 151.8 0.3 2e-44 151.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER26799.1 - 1.7e-09 37.9 0.3 2.4e-09 37.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EER26799.1 - 4.9e-06 26.2 0.1 1.2e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EER26799.1 - 0.00012 21.7 0.0 0.00046 19.7 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EER26799.1 - 0.00046 20.1 0.1 0.001 19.0 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Fungal_trans PF04082.18 EER26800.1 - 4.5e-10 39.0 0.0 4.9e-09 35.6 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26800.1 - 0.0001 22.3 7.2 0.0056 16.8 1.3 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain SSP160 PF06933.11 EER26800.1 - 8.9 4.4 21.2 16 3.6 21.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 adh_short_C2 PF13561.6 EER26801.1 - 4.1e-57 193.4 1.5 5.4e-57 193.0 1.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER26801.1 - 3e-54 183.4 1.0 3e-54 183.4 1.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EER26801.1 - 5.9e-13 49.1 2.3 1.6e-12 47.7 2.1 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EER26801.1 - 3.5e-08 33.2 0.1 4.9e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EER26801.1 - 5.2e-05 23.2 0.3 0.00012 22.1 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 EER26801.1 - 5.9e-05 22.6 0.3 9e-05 22.0 0.1 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EER26801.1 - 0.0025 17.0 1.1 0.013 14.6 0.3 2.2 2 1 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EER26801.1 - 0.0057 15.8 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_trans_4_4 PF13579.6 EER26801.1 - 0.006 17.0 0.4 5.2 7.5 0.2 2.3 2 1 0 2 2 2 2 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 EER26801.1 - 0.011 15.5 0.0 0.096 12.4 0.0 2.1 2 0 0 2 2 2 0 Starch synthase catalytic domain NAD_binding_7 PF13241.6 EER26801.1 - 0.014 15.8 0.2 0.097 13.1 0.1 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.6 EER26801.1 - 0.015 15.2 0.7 0.026 14.4 0.3 1.6 2 0 0 2 2 2 0 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 EER26801.1 - 0.026 13.9 1.4 0.031 13.6 0.5 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.15 EER26801.1 - 0.029 14.6 0.1 0.063 13.4 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 EER26801.1 - 0.044 13.2 0.1 0.076 12.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EER26801.1 - 0.049 13.3 0.1 0.21 11.2 0.2 1.9 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Oxidored_nitro PF00148.19 EER26801.1 - 0.079 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Exotox-A_cataly PF09009.10 EER26801.1 - 0.17 11.6 0.7 0.76 9.5 0.1 2.0 2 0 0 2 2 2 0 Exotoxin A catalytic NmrA PF05368.13 EER26801.1 - 0.23 11.0 1.1 0.42 10.1 1.1 1.4 1 0 0 1 1 1 0 NmrA-like family Ferric_reduct PF01794.19 EER26802.1 - 8.1e-25 87.4 6.2 8.1e-25 87.4 6.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EER26802.1 - 4.6e-14 52.8 0.1 4.5e-11 43.1 0.1 3.0 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EER26802.1 - 2.1e-10 40.7 0.0 1.7e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EER26802.1 - 0.0047 17.5 0.0 0.018 15.7 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain GAT PF03127.14 EER26803.1 - 4.4e-20 71.8 0.8 1.4e-19 70.2 0.8 1.9 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 EER26803.1 - 0.00065 19.6 0.4 0.0025 17.7 0.0 1.9 2 0 0 2 2 2 1 VHS domain DprA_WH PF17782.1 EER26803.1 - 0.11 12.6 0.5 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 DprA winged helix domain MscS_porin PF12795.7 EER26803.1 - 0.87 9.1 7.9 0.66 9.5 0.2 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain F-box-like PF12937.7 EER26804.1 - 0.0023 17.8 0.9 1.1 9.3 0.0 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 EER26804.1 - 0.012 15.5 1.5 0.17 11.8 0.0 2.8 2 0 0 2 2 2 0 F-box domain Cation_efflux PF01545.21 EER26805.1 - 6.4e-15 55.4 6.0 7.9e-15 55.1 6.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EER26805.1 - 3.3e-10 39.9 0.2 7.2e-10 38.9 0.2 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter PRIMA1 PF16101.5 EER26805.1 - 7.3 6.7 0.0 7.3 6.7 0.0 3.0 2 1 0 2 2 2 0 Proline-rich membrane anchor 1 2_5_RNA_ligase2 PF13563.6 EER26806.1 - 2.6e-29 102.1 0.0 6.9e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.17 EER26806.1 - 9.4e-21 73.9 0.0 3.3e-20 72.1 0.0 1.8 2 1 0 2 2 2 1 Poly(A) polymerase central domain MJ1316 PF04457.12 EER26806.1 - 1.6e-19 70.4 0.2 6.5e-19 68.4 0.1 2.2 2 0 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain Exo_endo_phos PF03372.23 EER26806.1 - 1.8e-08 34.2 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTP_transf_2 PF01909.23 EER26806.1 - 0.003 17.8 0.1 0.02 15.2 0.0 2.3 1 1 0 2 2 2 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.15 EER26806.1 - 0.074 12.7 0.2 2.4 7.7 0.3 2.3 1 1 1 2 2 2 0 Poly(A) polymerase predicted RNA binding domain PAP_assoc PF03828.19 EER26806.1 - 0.2 11.9 1.1 0.58 10.4 1.1 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase Aminotran_1_2 PF00155.21 EER26809.1 - 6.5e-22 78.2 0.0 8.3e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EER26809.1 - 0.0027 16.6 0.0 0.011 14.5 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.7 EER26810.1 - 5.1e-103 343.5 12.4 4.5e-88 294.7 8.4 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EER26810.1 - 1.4e-07 31.0 1.0 0.0064 16.2 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ndc1_Nup PF09531.10 EER26810.1 - 5.7 5.5 6.3 9.7 4.7 6.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Fungal_trans_2 PF11951.8 EER26811.1 - 1.5e-12 47.1 0.2 4.2e-07 29.1 0.4 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26811.1 - 1.6e-09 37.7 8.6 3.7e-09 36.6 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1970 PF09301.10 EER26812.1 - 0.038 14.3 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) AMP-binding PF00501.28 EER26813.1 - 7.2e-62 209.3 0.0 9.2e-62 209.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER26813.1 - 7.1e-08 33.3 0.3 1.5e-07 32.3 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATPgrasp_N PF18130.1 EER26814.1 - 1.2e-14 54.6 0.0 3.2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EER26814.1 - 2.6e-10 40.1 0.0 6.6e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EER26814.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EER26814.1 - 0.0043 17.1 0.1 0.11 12.5 0.0 2.8 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.11 EER26814.1 - 0.033 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain TTL PF03133.15 EER26814.1 - 0.22 10.6 0.0 1.3 8.1 0.0 1.9 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family AMP-binding PF00501.28 EER26815.1 - 1.2e-72 244.8 0.0 1.7e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EER26815.1 - 2.6e-08 34.1 0.1 5.1e-07 30.0 0.1 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 EER26815.1 - 3.9e-08 32.4 0.1 1.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Condensation domain AMP-binding_C PF13193.6 EER26815.1 - 5.7e-05 24.0 0.1 0.00029 21.8 0.1 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain AHJR-like PF18743.1 EER26815.1 - 0.072 12.6 0.1 0.81 9.3 0.0 2.2 2 0 0 2 2 2 0 REase_AHJR-like Cys_Met_Meta_PP PF01053.20 EER26816.1 - 4.7e-31 107.7 0.0 6.3e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EER26816.1 - 1.3e-05 24.6 0.0 2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II FMN_dh PF01070.18 EER26817.1 - 7.1e-111 370.6 0.0 8.3e-111 370.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EER26817.1 - 1.9e-07 30.4 0.2 5.8e-07 28.8 0.1 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EER26817.1 - 1.3e-06 27.9 0.0 2.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EER26817.1 - 0.011 15.2 0.2 0.25 10.7 0.0 2.6 2 1 1 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.14 EER26817.1 - 0.12 11.7 0.9 17 4.6 0.0 2.9 2 1 0 3 3 3 0 Thiazole biosynthesis protein ThiG FMO-like PF00743.19 EER26818.1 - 7.7e-48 163.2 0.0 3.5e-43 147.8 0.0 2.7 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EER26818.1 - 9e-17 61.3 0.0 2.1e-14 53.5 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER26818.1 - 2.3e-13 50.1 0.0 8.7e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EER26818.1 - 3.5e-08 33.4 3.5 0.012 15.2 0.3 4.2 4 0 0 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 EER26818.1 - 5.3e-07 29.1 0.1 3e-06 26.6 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EER26818.1 - 1.1e-06 28.8 1.2 7.3e-06 26.1 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 EER26818.1 - 1.7e-06 28.1 0.7 0.06 13.4 0.1 3.3 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EER26818.1 - 0.00014 22.2 0.3 0.038 14.4 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 EER26818.1 - 0.00021 21.8 2.7 0.07 13.7 0.4 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER26818.1 - 0.0003 20.8 0.7 0.0003 20.8 0.7 2.7 3 1 0 3 3 2 1 FAD-NAD(P)-binding ThiF PF00899.21 EER26818.1 - 0.0011 18.3 1.9 0.018 14.4 0.6 2.4 2 0 0 2 2 2 1 ThiF family 2-Hacid_dh_C PF02826.19 EER26818.1 - 0.0016 17.8 0.2 1 8.7 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Amino_oxidase PF01593.24 EER26818.1 - 0.0019 17.6 0.6 0.68 9.2 0.0 3.2 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_2 PF03446.15 EER26818.1 - 0.0028 17.8 0.0 0.26 11.4 0.0 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Thi4 PF01946.17 EER26818.1 - 0.0037 16.5 0.0 0.037 13.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EER26818.1 - 0.0049 16.2 0.3 0.22 10.7 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain IlvN PF07991.12 EER26818.1 - 0.019 14.6 0.1 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain adh_short PF00106.25 EER26818.1 - 0.049 13.1 1.7 0.71 9.3 0.3 2.3 2 0 0 2 2 2 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 EER26818.1 - 0.088 12.1 0.6 0.2 11.0 0.4 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MFS_1 PF07690.16 EER26819.1 - 1.4e-45 155.7 58.0 1.6e-43 149.0 55.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER26819.1 - 2.3e-13 49.5 33.7 5.2e-13 48.3 33.7 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 EER26820.1 - 1.6e-30 106.3 0.0 1.9e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 EER26821.1 - 8.1e-72 241.8 0.3 1.5e-71 240.9 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EER26821.1 - 4.5e-34 117.0 0.0 9.8e-34 115.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EER26821.1 - 6.3e-20 71.9 0.0 1.2e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EER26821.1 - 1.8e-19 70.1 0.0 3.9e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.25 EER26821.1 - 3.5e-13 49.7 0.7 7.5e-13 48.6 0.7 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_3 PF07859.13 EER26821.1 - 7.1e-13 48.9 0.0 3.2e-11 43.5 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold SAT PF16073.5 EER26821.1 - 1.8e-09 37.7 1.6 2.2e-07 30.9 0.0 3.2 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis KAsynt_C_assoc PF16197.5 EER26821.1 - 2.8e-09 37.4 0.0 9.7e-09 35.7 0.0 1.9 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension Peptidase_S9 PF00326.21 EER26821.1 - 4.3e-09 36.2 0.1 1.6e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EER26821.1 - 8.2e-06 25.5 0.0 0.00011 21.8 0.0 2.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Thiolase_N PF00108.23 EER26821.1 - 0.00074 19.0 0.4 0.0015 17.9 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EER26821.1 - 0.00076 20.1 1.3 0.0032 18.1 0.6 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER26821.1 - 0.0056 16.4 1.3 0.02 14.5 0.0 2.4 3 0 0 3 3 3 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER26821.1 - 0.0089 15.3 0.0 0.027 13.7 0.0 1.8 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EER26821.1 - 0.052 13.1 0.0 3 7.4 0.0 2.4 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 EER26821.1 - 0.19 11.5 0.0 0.65 9.8 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase COesterase PF00135.28 EER26821.1 - 0.23 10.3 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Beta_elim_lyase PF01212.21 EER26822.1 - 1.7e-59 201.5 0.0 2.2e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EER26822.1 - 0.011 15.1 0.4 0.22 10.8 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family HTH_Tnp_ISL3 PF13542.6 EER26822.1 - 0.013 14.9 0.1 0.2 11.1 0.0 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Pkinase PF00069.25 EER26823.1 - 6.1e-09 35.6 0.0 7.8e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EER26823.1 - 1.2e-06 27.6 0.0 1.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EER26823.1 - 0.038 13.3 0.0 0.047 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.7 EER26824.1 - 3.1e-29 101.4 0.3 2.6e-17 63.2 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER26824.1 - 1.4e-22 79.5 2.4 9.3e-10 38.6 0.1 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EER26824.1 - 2.5e-15 56.6 1.7 4.9e-09 36.6 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER26824.1 - 3.4e-15 54.6 0.5 0.0046 17.3 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EER26824.1 - 1e-14 54.2 3.4 0.00027 21.2 0.2 3.4 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.21 EER26824.1 - 0.013 15.5 10.2 0.013 15.5 10.2 1.7 2 0 0 2 2 2 0 bZIP transcription factor KCNQC3-Ank-G_bd PF11956.8 EER26824.1 - 0.063 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 APH PF01636.23 EER26825.1 - 1.1e-09 38.5 0.1 1.8e-09 37.9 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pyr_redox_2 PF07992.14 EER26826.1 - 2.6e-36 125.4 0.0 3.7e-35 121.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER26826.1 - 6.4e-09 36.3 0.0 3.8e-08 33.8 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER26826.1 - 0.03 14.3 0.0 0.095 12.7 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EER26826.1 - 0.13 12.5 0.0 28 5.1 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Amidase PF01425.21 EER26827.1 - 2.1e-89 300.6 0.0 2.7e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 EER26828.1 - 6.8e-45 153.4 0.3 8.4e-45 153.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER26828.1 - 2.4e-39 134.8 0.2 4.1e-39 134.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER26828.1 - 4e-11 43.2 0.1 6.7e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF429 PF04250.13 EER26828.1 - 0.036 13.9 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF429) DUF3431 PF11913.8 EER26829.1 - 3.2e-67 226.5 0.0 3.7e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Aldolase_II PF00596.21 EER26830.1 - 3.7e-47 160.7 0.2 4.7e-47 160.3 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GAPT PF11770.8 EER26831.1 - 0.012 15.5 0.3 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) HTH_29 PF13551.6 EER26831.1 - 0.11 12.5 1.6 0.13 12.3 0.3 1.8 2 0 0 2 2 2 0 Winged helix-turn helix MFS_1 PF07690.16 EER26832.1 - 5.6e-26 91.3 41.7 6.1e-19 68.2 10.0 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EER26832.1 - 1.3e-08 34.2 0.2 1.3e-08 34.2 0.2 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter AA_permease_2 PF13520.6 EER26834.1 - 4.3e-60 203.7 48.4 5.5e-60 203.4 48.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER26834.1 - 5e-21 74.8 38.1 8e-21 74.2 38.1 1.2 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 EER26834.1 - 0.024 14.6 0.0 0.024 14.6 0.0 3.0 3 0 0 3 3 3 0 LPXTG cell wall anchor motif ADH_zinc_N PF00107.26 EER26835.1 - 2.7e-16 59.7 0.0 5e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER26835.1 - 7.8e-12 46.4 0.0 1.6e-11 45.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER26835.1 - 5.1e-07 29.5 1.5 0.00015 21.6 0.0 2.6 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 EER26836.1 - 7.5e-39 133.6 33.7 7.5e-39 133.6 33.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER26836.1 - 1.1e-12 47.6 7.4 1.1e-12 47.6 7.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EER26836.1 - 1.3e-06 28.0 9.5 5e-06 26.1 4.5 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EER26836.1 - 2.4e-06 26.3 2.7 2.4e-06 26.3 2.7 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PTR2 PF00854.21 EER26836.1 - 0.025 13.4 7.2 0.068 12.0 7.2 1.7 1 1 0 1 1 1 0 POT family FA_desaturase PF00487.24 EER26836.1 - 7.4 6.3 25.3 0.53 10.1 4.2 3.0 1 1 2 3 3 3 0 Fatty acid desaturase Alpha-amylase PF00128.24 EER26837.1 - 9.8e-29 101.0 0.1 4e-28 99.0 0.1 1.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EER26837.1 - 1e-06 27.3 0.3 0.13 10.4 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EER26837.1 - 0.0015 18.6 0.2 0.0047 17.1 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) DUF3242 PF11586.8 EER26837.1 - 0.37 10.5 3.2 0.88 9.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3242) Pan3_PK PF18101.1 EER26838.1 - 2.4e-63 212.2 0.5 3.7e-63 211.6 0.5 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EER26838.1 - 1.4e-07 31.1 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3455 PF11937.8 EER26839.1 - 4.4e-38 131.1 0.0 5.4e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EER26839.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) Fibrillarin PF01269.17 EER26840.1 - 1.2e-104 348.3 0.0 1.5e-104 348.1 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EER26840.1 - 1.2e-06 28.4 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EER26840.1 - 0.032 14.0 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EER26840.1 - 0.045 13.4 0.0 0.09 12.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Epimerase PF01370.21 EER26841.1 - 1.4e-17 64.0 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EER26841.1 - 2.4e-13 49.7 0.0 3.2e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EER26841.1 - 5e-13 49.2 0.1 6.8e-13 48.7 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EER26841.1 - 6.3e-06 25.5 0.0 8.6e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EER26841.1 - 9.8e-05 21.6 0.3 0.0062 15.7 0.3 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EER26841.1 - 0.00012 21.7 0.0 0.0006 19.3 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EER26841.1 - 0.0005 20.0 0.0 0.00097 19.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.23 EER26841.1 - 0.0011 19.1 0.1 0.0063 16.6 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EER26841.1 - 0.0051 17.1 0.1 0.012 15.9 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EER26841.1 - 0.0059 15.8 0.0 0.04 13.1 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EER26841.1 - 0.017 15.0 0.1 0.041 13.8 0.1 1.5 1 1 1 2 2 2 0 NAD(P)H-binding NmrA PF05368.13 EER26841.1 - 0.15 11.6 0.1 0.47 10.0 0.1 1.8 2 0 0 2 2 2 0 NmrA-like family Peptidase_M16 PF00675.20 EER26842.1 - 2.9e-56 189.6 0.1 1.3e-55 187.5 0.1 2.1 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EER26842.1 - 1.2e-38 133.0 0.0 4.1e-37 128.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain FliH PF02108.16 EER26842.1 - 0.1 12.7 0.7 0.28 11.3 0.0 2.0 2 0 0 2 2 2 0 Flagellar assembly protein FliH SecIII_SopE_N PF05364.14 EER26842.1 - 0.23 11.6 0.9 15 5.7 0.2 2.6 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus MFS_1 PF07690.16 EER26843.1 - 1.4e-28 99.9 55.7 6.3e-26 91.1 48.8 3.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Orai-1 PF07856.12 EER26843.1 - 0.13 11.9 10.3 0.38 10.4 0.1 3.0 2 1 0 2 2 2 0 Mediator of CRAC channel activity ADH_zinc_N PF00107.26 EER26844.1 - 8.3e-21 74.3 0.0 1.1e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EER26844.1 - 2e-16 59.8 0.0 4.1e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EER26844.1 - 3.2e-10 41.2 0.0 5.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CybS PF05328.12 EER26845.1 - 1.4e-51 173.7 0.0 1.7e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Maf PF02545.14 EER26846.1 - 6.7e-48 162.7 0.0 7.9e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.26 EER26847.1 - 1.2e-09 38.0 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.12 EER26847.1 - 0.018 14.4 1.0 0.031 13.7 0.7 1.5 1 1 0 1 1 1 0 Umbravirus long distance movement (LDM) family GFA PF04828.14 EER26848.1 - 0.0086 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ribonuc_L-PSP PF01042.21 EER26851.1 - 5.7e-35 120.0 0.0 6.6e-35 119.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Jak1_Phl PF17887.1 EER26852.1 - 0.066 13.2 1.3 0.24 11.4 1.7 1.7 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain DUF5345 PF17280.2 EER26852.1 - 0.1 12.6 0.6 0.17 11.9 0.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5345) Zn_clus PF00172.18 EER26853.1 - 5.3e-08 32.9 9.1 8.7e-08 32.2 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EER26853.1 - 3.7e-07 29.3 0.1 7e-07 28.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain VWA PF00092.28 EER26854.1 - 4.3e-05 23.8 0.0 0.00053 20.3 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EER26854.1 - 0.03 15.0 0.0 0.092 13.4 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain ANAPC4 PF12896.7 EER26856.1 - 5e-67 225.4 0.1 8.8e-67 224.6 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EER26856.1 - 3.7e-33 113.7 0.0 3.7e-32 110.5 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EER26856.1 - 0.084 13.8 2.9 2 9.4 0.0 3.7 3 0 0 3 3 3 0 WD domain, G-beta repeat HEAT_EZ PF13513.6 EER26857.1 - 2.6e-13 50.1 8.3 7.7e-09 35.9 0.0 7.1 9 0 0 9 9 9 2 HEAT-like repeat HEAT PF02985.22 EER26857.1 - 4.9e-13 48.1 10.0 0.00012 22.1 0.0 8.2 8 1 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EER26857.1 - 1.4e-09 38.2 4.6 0.0017 18.7 0.2 6.2 4 1 2 6 6 6 4 HEAT repeats CLASP_N PF12348.8 EER26857.1 - 6.6e-07 29.1 0.7 0.26 10.8 0.0 4.7 3 2 1 5 5 5 2 CLASP N terminal Arm PF00514.23 EER26857.1 - 6.8e-07 29.1 0.8 0.68 10.1 0.1 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 EER26857.1 - 3e-06 27.1 0.2 6.8e-05 22.7 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ecm29 PF13001.7 EER26857.1 - 6.3e-05 21.9 0.4 0.013 14.2 0.1 3.2 2 1 1 3 3 3 1 Proteasome stabiliser DRIM PF07539.12 EER26857.1 - 0.0015 16.9 1.1 6.2 5.0 0.0 4.1 4 0 0 4 4 4 2 Down-regulated in metastasis HEAT_PBS PF03130.16 EER26857.1 - 0.0091 16.6 0.0 18 6.3 0.0 4.6 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat PMC2NT PF08066.12 EER26857.1 - 0.019 15.6 0.1 16 6.2 0.1 4.0 4 0 0 4 4 4 0 PMC2NT (NUC016) domain NUC173 PF08161.12 EER26857.1 - 0.093 12.4 2.1 15 5.2 0.2 3.5 4 0 0 4 4 4 0 NUC173 domain Ribosomal_S8 PF00410.19 EER26858.1 - 5.5e-22 78.1 0.3 8.4e-22 77.5 0.3 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 ubiquitin PF00240.23 EER26860.1 - 4.4e-07 29.5 0.0 9e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 EER26860.1 - 0.0072 16.9 0.1 0.021 15.4 0.1 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 EER26860.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.15 EER26861.1 - 9.2e-76 253.9 0.0 2.8e-75 252.3 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase E1-E2_ATPase PF00122.20 EER26862.1 - 9.3e-37 126.3 19.9 9.7e-32 109.9 0.6 3.5 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EER26862.1 - 3.4e-26 92.1 10.3 3.4e-26 92.1 10.3 3.0 2 2 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EER26862.1 - 4.9e-19 69.5 0.1 2.2e-17 64.0 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EER26862.1 - 1.3e-17 63.2 0.0 2.6e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EER26862.1 - 3.5e-16 59.1 0.0 9.6e-16 57.7 0.0 1.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EER26862.1 - 1.2e-06 28.5 0.3 0.0005 19.9 0.5 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EER26862.1 - 0.014 15.3 0.8 0.03 14.2 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Wzy_C PF04932.15 EER26862.1 - 1.6 8.4 6.1 0.26 10.9 0.0 2.7 3 0 0 3 3 3 0 O-Antigen ligase ANAPC10 PF03256.16 EER26863.1 - 1.7e-42 145.2 0.0 2.4e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Pox_Ag35 PF03286.14 EER26863.1 - 0.21 11.4 3.2 7.6 6.3 0.3 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Iso_dh PF00180.20 EER26864.1 - 1.1e-129 432.6 0.0 1.2e-129 432.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_23 PF13489.6 EER26865.1 - 1.2e-19 70.8 0.0 1.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER26865.1 - 4.7e-11 43.3 0.0 1.4e-10 41.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER26865.1 - 1.3e-07 31.5 0.0 0.018 14.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EER26865.1 - 1.4e-07 32.1 0.0 9.8e-07 29.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER26865.1 - 2e-07 31.6 0.0 4.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER26865.1 - 0.0047 16.5 0.0 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EER26865.1 - 0.0097 15.3 0.0 0.025 14.0 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EER26865.1 - 0.03 14.1 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 EER26865.1 - 0.057 12.9 0.0 0.51 9.8 0.0 2.2 2 1 0 2 2 2 0 Putative methyltransferase Methyltransf_2 PF00891.18 EER26865.1 - 0.13 11.5 0.0 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase domain CDP-OH_P_transf PF01066.21 EER26866.1 - 4e-13 49.9 0.7 4e-13 49.9 0.7 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.21 EER26867.1 - 6.7e-33 114.4 0.0 4.5e-28 98.6 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EER26867.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C DUF5587 PF17825.1 EER26868.1 - 0.0042 14.5 0.1 0.0056 14.0 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5587) TRAF_BIRC3_bd PF16673.5 EER26868.1 - 0.033 14.0 0.6 0.09 12.6 0.6 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain RRM_1 PF00076.22 EER26869.1 - 7.8e-41 137.7 0.5 1.4e-19 69.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EER26869.1 - 3.1e-24 85.8 0.2 9.6e-24 84.3 0.2 1.9 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EER26869.1 - 6.1e-05 22.8 0.0 0.097 12.5 0.0 2.9 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EER26869.1 - 0.034 14.2 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif PHM7_cyt PF14703.6 EER26869.1 - 0.092 13.0 0.0 16 5.6 0.0 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_7 PF16367.5 EER26869.1 - 0.19 11.9 0.0 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif Cyt-b5 PF00173.28 EER26870.1 - 1.1e-18 67.2 0.1 1.1e-18 67.2 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EER26870.1 - 1.7e-13 51.1 16.2 1.7e-13 51.1 16.2 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily OMPdecase PF00215.24 EER26871.1 - 3.3e-06 26.9 0.0 0.00031 20.4 0.0 2.3 2 0 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF1778 PF08681.11 EER26871.1 - 0.043 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) Cu-oxidase_2 PF07731.14 EER26872.1 - 4.8e-05 23.1 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Adap_comp_sub PF00928.21 EER26873.1 - 6.9e-21 74.8 0.1 1e-20 74.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EER26873.1 - 2.6e-07 30.7 0.1 4.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 EER26873.1 - 0.00094 19.6 0.2 0.0018 18.7 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.9 EER26874.1 - 1e-22 80.2 0.0 1.8e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Amidohydro_2 PF04909.14 EER26875.1 - 3.6e-24 86.1 0.0 4.2e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 EER26876.1 - 4e-21 75.3 0.0 6.8e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26876.1 - 2.3e-10 40.4 7.3 3.9e-10 39.7 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 EER26876.1 - 0.13 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Ran-binding PF05508.11 EER26876.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 RanGTP-binding protein Spc24 PF08286.11 EER26876.1 - 0.19 12.0 0.5 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PMT_2 PF13231.6 EER26876.1 - 0.21 11.8 0.2 0.43 10.8 0.2 1.5 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Opy2 PF09463.10 EER26876.1 - 7.1 7.0 8.9 0.98 9.8 3.3 2.2 1 1 0 2 2 2 0 Opy2 protein tRNA-synt_2b PF00587.25 EER26877.1 - 2.8e-35 121.9 0.0 5e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EER26877.1 - 2.8e-05 24.2 0.0 7.9e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain DUF4224 PF13986.6 EER26877.1 - 0.027 14.3 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Borealin PF10512.9 EER26877.1 - 0.15 12.0 1.4 0.34 10.9 1.4 1.5 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 p450 PF00067.22 EER26878.1 - 7.6e-35 120.5 0.0 1.1e-34 120.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ECH_1 PF00378.20 EER26879.1 - 2.9e-41 141.5 0.0 5.8e-41 140.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER26879.1 - 5.2e-29 101.8 0.0 1.1e-28 100.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DNase-RNase PF02577.14 EER26879.1 - 0.076 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Bifunctional nuclease Pyr_redox_2 PF07992.14 EER26880.1 - 4e-57 193.7 0.2 6.9e-57 192.9 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EER26880.1 - 2e-31 108.5 0.2 4e-31 107.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EER26880.1 - 2.7e-14 53.5 2.7 3.9e-14 53.0 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER26880.1 - 3.6e-10 39.6 0.3 6.1e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EER26880.1 - 0.00025 21.0 0.1 0.00025 21.0 0.1 2.0 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EER26880.1 - 0.0018 17.4 1.8 0.36 9.9 0.4 2.7 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_oxidored PF12831.7 EER26880.1 - 0.0038 16.6 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EER26880.1 - 0.0049 16.0 0.0 0.01 15.0 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EER26880.1 - 0.0091 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_Gly3P_dh_N PF01210.23 EER26880.1 - 0.082 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.14 EER26880.1 - 0.28 9.8 2.1 3.1 6.4 0.3 2.8 3 1 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 EER26880.1 - 1.6 7.8 9.9 2.3 7.2 1.0 3.0 4 0 0 4 4 4 0 FAD binding domain Pkinase PF00069.25 EER26881.1 - 8.9e-54 182.6 0.0 3.5e-51 174.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER26881.1 - 6.9e-31 107.5 0.0 5.5e-30 104.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EER26881.1 - 0.0025 16.9 0.1 0.0041 16.2 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EER26881.1 - 0.0052 15.6 0.0 0.0081 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EER26881.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 EER26881.1 - 0.061 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Mem_trans PF03547.18 EER26882.1 - 8.7e-48 162.6 3.0 2.7e-47 161.0 3.0 1.7 1 1 0 1 1 1 1 Membrane transport protein Peptidase_C12 PF01088.21 EER26883.1 - 4.7e-70 235.6 0.0 5.7e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EER26883.1 - 5.4e-10 39.0 0.0 1.3e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Fungal_trans_2 PF11951.8 EER26884.1 - 7.5e-09 34.9 3.2 1.4e-08 34.0 3.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26884.1 - 1.5e-07 31.4 14.2 2.8e-07 30.6 14.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3865 PF12981.7 EER26884.1 - 0.25 11.2 0.4 0.4 10.5 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) Choline_kinase PF01633.20 EER26885.1 - 4.6e-63 212.6 0.0 1.1e-62 211.4 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EER26885.1 - 4e-14 52.0 0.0 8.8e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EER26885.1 - 5.1e-05 23.3 0.1 0.00026 21.0 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family HEAT_EZ PF13513.6 EER26886.1 - 1.1e-31 108.8 11.6 1.7e-16 60.3 0.0 10.0 9 2 2 11 11 10 3 HEAT-like repeat HEAT PF02985.22 EER26886.1 - 5.2e-28 94.7 13.2 3.3e-05 23.8 0.0 11.7 12 0 0 12 12 10 6 HEAT repeat HEAT_2 PF13646.6 EER26886.1 - 1.1e-19 70.6 0.1 0.00093 19.5 0.0 7.3 4 2 3 7 7 7 3 HEAT repeats Cnd1 PF12717.7 EER26886.1 - 1.6e-12 47.7 0.0 8.9e-06 25.8 0.0 4.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EER26886.1 - 2.5e-10 40.1 0.0 0.014 14.5 0.0 4.9 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EER26886.1 - 3.4e-09 37.2 0.0 0.097 13.3 0.0 5.7 5 2 3 8 8 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EER26886.1 - 5.2e-08 31.9 2.1 0.005 15.5 0.2 3.6 3 2 0 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.8 EER26886.1 - 5.9e-08 32.6 0.2 4.2 6.9 0.0 6.8 5 3 2 7 7 7 1 CLASP N terminal Arm PF00514.23 EER26886.1 - 2.8e-06 27.2 0.3 0.57 10.3 0.0 5.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EER26886.1 - 0.00024 21.5 0.2 0.35 11.7 0.0 4.0 3 0 0 3 3 2 1 PBS lyase HEAT-like repeat Xpo1 PF08389.12 EER26886.1 - 0.00025 21.1 0.0 0.033 14.2 0.0 3.9 3 2 0 3 3 3 1 Exportin 1-like protein UME PF08064.13 EER26886.1 - 0.0019 18.1 0.0 2.4 8.1 0.0 4.1 2 1 1 3 3 3 1 UME (NUC010) domain RTP1_C1 PF10363.9 EER26886.1 - 0.0028 17.8 0.3 0.46 10.7 0.0 3.6 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3437 PF11919.8 EER26886.1 - 0.0035 17.2 0.0 0.11 12.4 0.0 3.1 3 0 0 3 3 2 1 Domain of unknown function (DUF3437) RIX1 PF08167.12 EER26886.1 - 0.0056 16.4 0.0 12 5.6 0.0 4.4 3 1 0 4 4 4 0 rRNA processing/ribosome biogenesis IBN_N PF03810.19 EER26886.1 - 0.013 15.4 0.1 2.8 7.9 0.0 4.4 4 1 0 4 4 3 0 Importin-beta N-terminal domain TIP120 PF08623.10 EER26886.1 - 0.021 14.6 0.0 0.84 9.4 0.0 3.3 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) V-ATPase_H_C PF11698.8 EER26886.1 - 0.049 13.8 0.0 3.6 7.7 0.0 2.9 3 0 0 3 3 3 0 V-ATPase subunit H UPF0253 PF06786.12 EER26886.1 - 0.11 12.7 0.2 4.7 7.6 0.1 2.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) Nipped-B_C PF12830.7 EER26886.1 - 0.17 11.8 0.6 23 4.9 0.0 3.4 4 1 0 4 4 3 0 Sister chromatid cohesion C-terminus YL1 PF05764.13 EER26886.1 - 1.3 9.0 4.8 2.2 8.3 4.8 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Syja_N PF02383.18 EER26887.1 - 1.3e-91 307.3 0.0 2.1e-91 306.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EER26887.1 - 7e-41 138.5 0.0 1.2e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Mg_trans_NIPA PF05653.14 EER26888.1 - 4.2e-103 344.5 16.0 5e-103 344.3 16.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EER26888.1 - 8.3e-05 22.8 7.1 8.3e-05 22.8 7.1 3.4 3 1 0 3 3 3 2 EamA-like transporter family Acyl_transf_3 PF01757.22 EER26888.1 - 3.2 6.7 21.5 0.36 9.8 9.6 2.2 1 1 1 2 2 2 0 Acyltransferase family Glyco_transf_28 PF03033.20 EER26889.1 - 1.7e-19 70.2 0.0 5.3e-12 46.0 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EER26889.1 - 6.7e-06 25.2 0.0 1.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EER26889.1 - 0.00018 21.8 0.0 0.0035 17.6 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 EER26889.1 - 0.062 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DASH_Ask1 PF08655.10 EER26890.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 DASH complex subunit Ask1 Imm27 PF15590.6 EER26890.1 - 0.13 12.0 0.1 0.82 9.5 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 27 APH PF01636.23 EER26891.1 - 2.2e-15 57.2 0.0 7e-15 55.6 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER26891.1 - 7.3e-06 25.7 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EER26891.1 - 0.053 12.4 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Glyco_hydro_31 PF01055.26 EER26892.1 - 4.3e-106 355.7 5.7 2.7e-55 188.3 0.9 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EER26892.1 - 8.4e-22 77.6 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase MFS_1 PF07690.16 EER26893.1 - 3.9e-19 68.8 39.6 3.9e-13 49.0 22.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER26893.1 - 3.2e-13 49.4 23.4 2.6e-12 46.4 23.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter ATP-synt_G PF04718.15 EER26895.1 - 5.1e-33 113.9 0.3 9e-33 113.1 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DEAD PF00270.29 EER26896.1 - 1.7e-25 89.8 0.0 1.7e-24 86.6 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER26896.1 - 8.1e-24 84.1 0.1 2.6e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER26896.1 - 1.7e-06 28.1 0.1 4.4e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EER26896.1 - 0.00078 18.3 0.0 0.018 13.8 0.0 2.3 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 T4SS-DNA_transf PF02534.14 EER26896.1 - 0.049 12.4 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DJ-1_PfpI PF01965.24 EER26896.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Methyltransf_16 PF10294.9 EER26897.1 - 6.5e-22 78.1 0.0 1.1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EER26897.1 - 5.1e-07 29.7 0.0 8.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER26897.1 - 0.028 15.1 0.0 0.34 11.7 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EER26897.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain VPS28 PF03997.12 EER26898.1 - 4.2e-73 245.1 0.0 4.9e-73 244.9 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.13 EER26899.1 - 1.2e-127 425.3 0.1 2e-127 424.5 0.1 1.4 1 0 0 1 1 1 1 Noc2p family Piwi PF02171.17 EER26900.1 - 1.4e-77 261.0 0.1 1.9e-77 260.5 0.1 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL1 PF08699.10 EER26900.1 - 1.8e-17 62.7 0.1 4.1e-17 61.6 0.1 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EER26900.1 - 2.4e-13 50.9 0.1 5.1e-13 49.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 EER26900.1 - 4.3e-13 49.3 0.0 1e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 EER26900.1 - 9.1e-06 25.9 0.0 2.3e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain MoaC PF01967.21 EER26901.1 - 7.1e-45 152.4 0.2 1.1e-44 151.8 0.2 1.3 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EER26901.1 - 2.2e-36 124.6 0.1 6.1e-35 119.9 0.0 2.3 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EER26901.1 - 2.3e-27 96.4 0.0 4e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EER26901.1 - 0.00012 22.3 0.0 0.00027 21.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain AA_permease PF00324.21 EER26902.1 - 1.5e-145 485.5 38.1 1.8e-145 485.2 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER26902.1 - 1.1e-36 126.6 39.3 1.3e-36 126.4 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease ANAPC4_WD40 PF12894.7 EER26903.1 - 0.00082 19.6 0.0 0.048 14.0 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EER26903.1 - 0.0027 18.5 0.0 7.5 7.6 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.12 EER26903.1 - 0.069 11.1 0.0 1.7 6.6 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Ribosomal_S25 PF03297.15 EER26904.1 - 1.1e-39 134.7 5.4 1.2e-39 134.5 5.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.12 EER26904.1 - 0.0045 16.7 0.1 0.0062 16.3 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 EER26904.1 - 0.019 15.3 0.1 0.029 14.7 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator HTH_11 PF08279.12 EER26904.1 - 0.022 14.7 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 HTH domain HTH_24 PF13412.6 EER26904.1 - 0.041 13.4 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.7 EER26904.1 - 0.074 13.0 0.1 0.095 12.6 0.1 1.2 1 0 0 1 1 1 0 MarR family TrmB PF01978.19 EER26904.1 - 0.08 12.8 0.3 0.1 12.5 0.3 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Cyt-b5 PF00173.28 EER26905.1 - 9.5e-11 41.7 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.12 EER26906.1 - 1.5e-69 233.9 0.2 2.3e-69 233.3 0.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EER26906.1 - 5.4e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 EER26906.1 - 0.0016 18.2 0.1 0.003 17.4 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EER26906.1 - 0.0043 17.1 0.0 0.011 15.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EER26906.1 - 0.0053 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EER26906.1 - 0.0088 15.5 0.1 0.023 14.1 0.0 1.8 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EER26906.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EER26906.1 - 0.038 13.1 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.6 EER26906.1 - 0.097 13.0 0.0 0.22 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain His_Phos_2 PF00328.22 EER26907.1 - 7.3e-13 48.6 0.0 2.1e-10 40.5 0.0 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Beta-TrCP_D PF12125.8 EER26907.1 - 0.21 11.5 0.2 0.49 10.3 0.2 1.6 1 0 0 1 1 1 0 D domain of beta-TrCP Lactamase_B_4 PF13691.6 EER26908.1 - 8.6e-29 99.0 0.1 3.4e-27 93.9 0.1 2.6 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EER26908.1 - 3.1e-14 52.9 0.0 5.4e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EER26908.1 - 0.017 15.1 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily bZIP_1 PF00170.21 EER26909.1 - 6.2e-08 32.6 9.6 6.2e-08 32.6 9.6 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EER26909.1 - 0.0084 16.2 8.9 0.0084 16.2 8.9 3.3 3 1 0 3 3 3 1 Basic region leucine zipper PilO PF04350.13 EER26909.1 - 0.025 14.7 0.1 0.025 14.7 0.1 2.7 3 0 0 3 3 3 0 Pilus assembly protein, PilO Dus PF01207.17 EER26910.1 - 1e-59 202.2 0.0 2.3e-59 201.0 0.0 1.6 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EER26910.1 - 0.018 14.3 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Fungal_trans_2 PF11951.8 EER26911.1 - 4.3e-27 94.9 1.4 6.1e-27 94.4 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26911.1 - 7.2e-07 29.2 9.3 1.5e-06 28.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIF PF01187.18 EER26912.1 - 3.7e-11 43.3 0.0 6.1e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Macro PF01661.21 EER26913.1 - 1.5e-11 44.3 0.0 5.1e-07 29.8 0.0 2.3 2 0 0 2 2 2 2 Macro domain CENP-X PF09415.10 EER26914.1 - 2e-24 85.7 0.5 3.8e-24 84.8 0.5 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X RepB-RCR_reg PF10723.9 EER26914.1 - 2.2 8.3 5.1 7.9 6.5 1.1 2.2 2 0 0 2 2 2 0 Replication regulatory protein RepB CN_hydrolase PF00795.22 EER26915.1 - 2.3e-39 135.3 0.0 3.9e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EER26915.1 - 5.2e-23 81.4 0.0 2.9e-22 79.0 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Cu_bind_like PF02298.17 EER26916.1 - 0.0016 18.4 0.2 0.0072 16.3 0.2 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain Mis12 PF05859.12 EER26917.1 - 1.3e-45 154.8 0.1 2e-45 154.2 0.1 1.3 1 0 0 1 1 1 1 Mis12 protein HU-CCDC81_bac_2 PF18175.1 EER26917.1 - 0.044 13.7 0.0 33 4.4 0.0 3.3 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 BCNT PF07572.12 EER26918.1 - 1.1e-24 86.3 0.3 2.4e-24 85.2 0.3 1.6 1 0 0 1 1 1 1 Bucentaur or craniofacial development Mo-co_dimer PF03404.16 EER26919.1 - 0.2 11.7 0.1 0.31 11.0 0.1 1.2 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Zn_clus PF00172.18 EER26920.1 - 6.9e-06 26.1 10.6 6.9e-06 26.1 10.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EER26920.1 - 0.0014 17.5 1.3 0.007 15.2 1.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3357 PF11837.8 EER26920.1 - 0.034 14.6 0.1 16 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Epimerase PF01370.21 EER26921.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Rad51 PF08423.11 EER26922.1 - 1.4e-127 424.3 0.0 1.7e-127 424.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EER26922.1 - 1.7e-09 37.6 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EER26922.1 - 6.3e-09 35.7 0.0 8.5e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EER26922.1 - 2.9e-07 31.0 0.8 7.3e-07 29.7 0.3 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EER26922.1 - 0.00012 21.5 0.3 0.00038 19.9 0.3 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EER26922.1 - 0.0031 16.9 0.1 0.016 14.5 0.0 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain ssDNA_TraI_N PF18272.1 EER26922.1 - 0.082 12.9 1.6 0.19 11.8 0.1 2.2 3 0 0 3 3 3 0 single-stranded DNA binding TraI N-terminal subdomain HhH-GPD PF00730.25 EER26922.1 - 0.1 13.1 0.0 2.2 8.8 0.0 2.1 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein AAA_24 PF13479.6 EER26922.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EER26922.1 - 0.15 12.3 0.2 0.56 10.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain PAXNEB PF05625.11 EER26922.1 - 0.19 10.8 1.3 0.57 9.3 0.4 1.8 1 1 1 2 2 2 0 PAXNEB protein PAN_1 PF00024.26 EER26924.1 - 7.2e-12 45.1 27.9 7.3e-05 22.7 1.0 3.9 3 1 1 4 4 4 3 PAN domain PAN_4 PF14295.6 EER26924.1 - 2.7e-10 40.0 18.9 0.00023 21.0 0.3 4.6 4 0 0 4 4 4 4 PAN domain MANEC PF07502.14 EER26924.1 - 0.0063 16.8 25.6 0.31 11.3 3.2 3.8 3 1 1 4 4 4 3 MANEC domain PAN_3 PF08277.12 EER26924.1 - 0.75 9.6 22.0 0.34 10.8 0.4 3.8 3 2 0 3 3 3 0 PAN-like domain 2OG-FeII_Oxy_3 PF13640.6 EER26925.1 - 9.5e-11 42.5 0.0 1.5e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PAN_1 PF00024.26 EER26926.1 - 2.1e-11 43.6 26.3 5.3e-06 26.3 3.8 3.9 3 2 1 4 4 4 3 PAN domain PAN_3 PF08277.12 EER26926.1 - 5.4e-11 42.1 14.1 2.8e-07 30.3 0.3 4.1 3 1 1 4 4 4 3 PAN-like domain PAN_4 PF14295.6 EER26926.1 - 6e-05 22.9 23.4 0.014 15.3 0.8 4.8 4 0 0 4 4 4 3 PAN domain MANEC PF07502.14 EER26926.1 - 0.002 18.4 1.5 0.002 18.4 1.5 3.7 3 1 0 3 3 3 2 MANEC domain p450 PF00067.22 EER26927.1 - 5.5e-70 236.4 0.0 6.8e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EER26928.1 - 1.1e-46 159.4 15.7 1.4e-46 159.0 15.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER26928.1 - 6.1e-11 41.9 2.6 6.1e-11 41.9 2.6 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EER26928.1 - 1.4e-09 37.0 3.6 1.9e-09 36.5 3.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EER26928.1 - 0.0025 16.8 3.6 0.0025 16.8 3.6 2.5 3 0 0 3 3 3 1 MFS_1 like family OATP PF03137.20 EER26928.1 - 0.083 11.2 1.5 0.25 9.6 1.5 1.7 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EER26928.1 - 0.12 10.8 5.7 0.2 10.0 5.7 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector NACHT PF05729.12 EER26929.1 - 1.3e-05 25.2 0.0 4.4e-05 23.5 0.0 2.0 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 EER26929.1 - 0.045 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EER26929.1 - 0.08 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EER26929.1 - 0.23 11.2 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EER26929.1 - 0.38 11.7 9.2 66 4.6 0.2 5.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Fructosamin_kin PF03881.14 EER26930.1 - 3.6e-29 101.9 0.0 4.6e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EER26930.1 - 2.1e-05 24.6 0.2 3.5e-05 23.8 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER26930.1 - 0.014 15.0 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EER26930.1 - 0.021 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase DIOX_N PF14226.6 EER26931.1 - 8.6e-11 42.6 0.0 1.6e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EER26931.1 - 6.8e-08 32.9 0.0 3.3e-07 30.7 0.0 2.0 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.28 EER26932.1 - 7.8e-33 114.7 0.0 1.1e-31 110.9 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EER26932.1 - 0.051 13.2 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ctr PF04145.15 EER26933.1 - 1.2e-40 139.5 0.5 1.5e-40 139.2 0.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.6 EER26933.1 - 0.36 10.9 8.3 0.83 9.7 4.4 2.0 1 1 1 2 2 2 0 Putative sensor Smg4_UPF3 PF03467.15 EER26934.1 - 3.9e-40 137.7 0.0 3.9e-40 137.7 0.0 2.8 3 0 0 3 3 3 1 Smg-4/UPF3 family RRM_1 PF00076.22 EER26934.1 - 1.2e-09 37.8 0.0 1.5e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Wyosine_form PF08608.12 EER26935.1 - 3.7e-22 78.4 0.0 9e-22 77.2 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EER26935.1 - 1.6e-21 77.4 0.1 4.8e-21 75.8 0.1 1.9 1 1 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EER26935.1 - 9.7e-10 38.8 0.0 3.2e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin NAM-associated PF14303.6 EER26935.1 - 0.6 10.8 5.9 1.2 9.9 5.9 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pro_dh PF01619.18 EER26936.1 - 2.8e-62 210.9 3.5 3.2e-62 210.7 3.5 1.0 1 0 0 1 1 1 1 Proline dehydrogenase OSK PF17182.4 EER26936.1 - 0.026 13.8 0.1 0.048 12.9 0.1 1.4 1 0 0 1 1 1 0 OSK domain OCD_Mu_crystall PF02423.15 EER26937.1 - 5.8e-15 55.0 0.0 5.9e-14 51.7 0.0 2.2 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EER26937.1 - 6.8e-07 29.4 0.0 0.0012 18.9 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.18 EER26938.1 - 8.3e-06 25.8 10.3 1.3e-05 25.2 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EER26939.1 - 8e-39 133.5 51.5 1e-37 129.9 49.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER26939.1 - 1.5e-07 30.7 11.7 1.5e-07 30.7 11.7 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter Saf_2TM PF18303.1 EER26939.1 - 0.09 12.4 0.2 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain DUF2052 PF09747.9 EER26939.1 - 0.74 9.9 10.9 1.1 9.3 10.9 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Aldedh PF00171.22 EER26940.1 - 3.8e-186 619.1 0.1 4.3e-186 618.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EER26940.1 - 0.1 12.0 0.0 16 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Putative_PNPOx PF01243.20 EER26941.1 - 2.5e-06 27.6 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AtuA PF07287.11 EER26942.1 - 3.5e-128 427.2 0.1 4.1e-128 427.0 0.1 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Mre11_DNA_bind PF04152.14 EER26943.1 - 4.3e-56 189.9 0.1 4.3e-56 189.9 0.1 2.1 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EER26943.1 - 1.9e-14 54.6 0.9 3.6e-14 53.7 0.9 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SIKE PF05769.11 EER26943.1 - 0.0017 18.3 0.6 0.0034 17.3 0.6 1.5 1 0 0 1 1 1 1 SIKE family Metallophos_2 PF12850.7 EER26943.1 - 0.0021 18.3 0.0 0.02 15.1 0.0 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PPL4 PF18188.1 EER26943.1 - 0.076 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Prim-pol 4 Dicty_REP PF05086.12 EER26943.1 - 7.6 4.4 5.6 19 3.0 5.6 1.6 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box-like PF12937.7 EER26944.1 - 5.4e-09 35.8 0.1 1.2e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER26944.1 - 2e-08 33.9 0.6 4.7e-08 32.7 0.2 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EER26944.1 - 0.056 13.3 0.1 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 F-box Glyco_hydro_72 PF03198.14 EER26945.1 - 6.1e-123 410.1 0.5 7.8e-123 409.7 0.5 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EER26945.1 - 1.7e-05 24.4 0.1 0.0014 18.1 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) MAS20 PF02064.15 EER26946.1 - 4.5e-44 149.7 0.2 5.4e-44 149.4 0.2 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor PMC2NT PF08066.12 EER26946.1 - 0.058 14.1 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Exo84_C PF16528.5 EER26947.1 - 1.7e-67 227.3 0.1 1.7e-67 227.3 0.1 2.2 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EER26947.1 - 2.8e-17 62.6 3.6 3.2e-17 62.4 1.8 2.1 2 0 0 2 2 2 1 Vps51/Vps67 DUF2594 PF10769.9 EER26947.1 - 0.022 14.8 0.2 0.054 13.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) COG2 PF06148.11 EER26947.1 - 0.072 13.2 1.8 0.12 12.4 0.1 2.3 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF5035 PF16438.5 EER26947.1 - 0.13 12.1 0.4 0.44 10.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5035) Exonuc_VII_L PF02601.15 EER26947.1 - 0.41 10.2 3.8 1.4 8.4 0.6 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF2130 PF09903.9 EER26947.1 - 0.5 9.6 5.0 3.1 7.0 0.2 2.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) BST2 PF16716.5 EER26947.1 - 1.2 9.8 8.5 2.8 8.6 1.7 3.0 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Baculo_PEP_C PF04513.12 EER26947.1 - 1.4 8.9 5.6 0.59 10.2 0.9 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 EER26947.1 - 1.9 6.4 4.5 0.35 8.8 0.3 1.7 2 0 0 2 2 2 0 Prominin ABC_tran PF00005.27 EER26949.1 - 7.6e-23 81.5 0.0 1.6e-11 44.8 0.0 3.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EER26949.1 - 3e-08 33.8 5.6 0.0074 16.1 0.0 3.3 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EER26949.1 - 9.6e-05 22.5 0.0 0.11 12.8 0.0 2.6 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit CPSase_L_D2 PF02786.17 EER26950.1 - 4.8e-113 375.8 0.4 5.2e-84 281.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EER26950.1 - 3.1e-48 162.8 0.0 6.5e-48 161.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EER26950.1 - 5.8e-47 159.9 0.0 1.6e-46 158.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EER26950.1 - 2.7e-44 150.8 0.1 6e-44 149.6 0.1 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EER26950.1 - 2.5e-39 134.4 0.0 5.4e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EER26950.1 - 1.8e-25 89.9 0.0 4.9e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EER26950.1 - 2.7e-22 78.8 0.0 9.1e-22 77.1 0.0 2.0 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EER26950.1 - 9.9e-20 70.9 0.6 1.7e-09 37.5 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EER26950.1 - 3.4e-16 59.3 0.2 1.2e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EER26950.1 - 1.9e-09 37.3 0.0 0.00027 20.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EER26950.1 - 3.2e-06 27.3 0.4 0.021 14.9 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EER26950.1 - 1.3e-05 25.1 0.2 0.0012 18.6 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EER26950.1 - 0.00014 21.7 0.8 0.17 11.6 0.0 4.5 5 0 0 5 5 5 1 DJ-1/PfpI family RimK PF08443.11 EER26950.1 - 0.0023 17.6 0.0 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.19 EER26950.1 - 0.0043 16.8 0.2 1.4 8.6 0.0 2.8 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.18 EER26950.1 - 0.022 15.0 1.7 0.088 13.1 0.0 2.8 3 0 0 3 3 2 0 TrkA-N domain Ion_trans PF00520.31 EER26951.1 - 6.7e-07 28.8 33.5 1e-06 28.2 33.5 1.3 1 0 0 1 1 1 1 Ion transport protein DUF3693 PF12472.8 EER26951.1 - 0.11 12.1 0.9 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 Phage related protein Synaptobrevin PF00957.21 EER26952.1 - 1.8e-32 111.0 0.0 2.4e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EER26952.1 - 5.5e-29 100.0 0.1 1e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ribosomal_L26 PF16906.5 EER26953.1 - 1.1e-38 131.6 2.6 1.4e-38 131.2 2.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EER26953.1 - 9.4e-09 34.9 2.1 2.1e-08 33.8 2.1 1.6 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 EER26953.1 - 0.024 14.7 0.2 0.027 14.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) FOXP-CC PF16159.5 EER26954.1 - 0.053 14.2 4.7 0.45 11.2 0.4 2.8 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 EER26954.1 - 0.069 13.3 0.5 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger AT_hook PF02178.19 EER26954.1 - 0.15 12.0 15.8 0.12 12.4 3.8 3.4 2 0 0 2 2 2 0 AT hook motif DFRP_C PF16543.5 EER26955.1 - 8.3e-26 90.3 10.6 8.3e-26 90.3 10.6 4.0 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EER26955.1 - 6.9e-07 29.0 1.6 6.9e-07 29.0 1.6 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EER26955.1 - 4.4e-05 23.4 5.8 4.4e-05 23.4 5.8 3.2 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH_4 PF18044.1 EER26955.1 - 5.3e-05 22.9 8.6 0.00099 18.9 1.5 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 EER26955.1 - 0.00016 22.4 8.0 0.00016 22.4 8.0 3.6 2 2 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 EER26955.1 - 0.0059 16.8 5.9 0.036 14.3 0.8 2.7 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EER26955.1 - 0.021 15.3 14.1 0.029 14.9 4.0 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Spt20 PF12090.8 EER26955.1 - 5.4 6.6 11.3 11 5.6 11.3 1.5 1 0 0 1 1 1 0 Spt20 family Polyoma_lg_T_C PF06431.11 EER26955.1 - 5.6 5.7 10.2 0.073 11.9 1.9 1.9 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus CS PF04969.16 EER26956.1 - 0.0027 18.7 0.0 0.005 17.8 0.0 1.5 1 0 0 1 1 1 1 CS domain Snf7 PF03357.21 EER26957.1 - 9.7e-22 77.4 11.6 1.1e-21 77.2 9.3 1.8 1 1 1 2 2 2 1 Snf7 DUF5059 PF16502.5 EER26957.1 - 0.034 12.9 0.2 0.05 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5059) DUF2408 PF10303.9 EER26957.1 - 0.082 13.5 2.2 0.14 12.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Hairpins PF04877.12 EER26957.1 - 0.11 12.1 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 HrpZ MerR-DNA-bind PF09278.11 EER26957.1 - 1.6 9.4 13.8 7.1 7.2 1.3 4.3 4 1 1 5 5 5 0 MerR, DNA binding RRM_1 PF00076.22 EER26958.1 - 2.5e-15 56.0 0.0 4.1e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER26958.1 - 1.9e-06 27.7 0.1 3.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif FoP_duplication PF13865.6 EER26958.1 - 4e-05 24.1 0.5 4e-05 24.1 0.5 2.8 2 1 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_7 PF16367.5 EER26958.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif HSP33 PF01430.19 EER26958.1 - 0.1 12.0 0.1 0.26 10.7 0.0 1.6 2 0 0 2 2 2 0 Hsp33 protein Lin-8 PF03353.15 EER26959.1 - 0.11 12.0 1.0 0.13 11.8 1.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4482 PF14818.6 EER26962.1 - 0.046 14.6 0.9 0.046 14.6 0.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) CLN3 PF02487.17 EER26962.1 - 0.082 11.9 0.1 0.082 11.9 0.1 1.6 2 0 0 2 2 2 0 CLN3 protein DUF501 PF04417.12 EER26962.1 - 0.098 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) NEMP PF10225.9 EER26962.1 - 0.87 9.2 4.7 0.096 12.3 0.4 1.6 2 0 0 2 2 2 0 NEMP family TIMELESS PF04821.14 EER26962.1 - 3.1 7.0 5.0 0.34 10.1 0.3 1.7 2 0 0 2 2 2 0 Timeless protein BTB PF00651.31 EER26963.1 - 1.1e-18 67.4 0.0 2.3e-18 66.4 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain DUF1247 PF06851.11 EER26963.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1247) Dynamin_N PF00350.23 EER26964.1 - 3.8e-38 131.2 0.0 7.2e-38 130.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EER26964.1 - 8.1e-22 77.8 1.1 1.6e-16 60.4 0.2 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EER26964.1 - 1e-05 25.5 0.0 3.9e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EER26964.1 - 0.0033 17.2 0.7 0.036 13.8 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EER26964.1 - 0.14 12.0 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_75 PF07335.11 EER26965.1 - 5e-58 196.0 0.3 6.4e-58 195.6 0.3 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 adh_short PF00106.25 EER26966.1 - 1.2e-26 93.4 0.0 1.5e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER26966.1 - 5.8e-22 78.4 0.0 7.6e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER26966.1 - 1.8e-05 24.8 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EER26966.1 - 0.0039 16.6 0.0 0.0054 16.1 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF460 PF04312.13 EER26966.1 - 0.013 15.2 0.1 0.021 14.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) ABC2_membrane PF01061.24 EER26967.1 - 1.9e-80 269.3 62.7 1.2e-46 158.8 24.8 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EER26967.1 - 2.2e-37 128.6 0.0 1.8e-18 67.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EER26967.1 - 2.2e-24 85.1 0.0 2.2e-24 85.1 0.0 3.4 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EER26967.1 - 5.2e-11 43.0 0.1 1.9e-10 41.2 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EER26967.1 - 2.2e-10 40.2 41.1 3.5e-08 32.9 19.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EER26967.1 - 1.5e-06 28.2 0.1 2.1e-05 24.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EER26967.1 - 0.00012 22.4 0.3 0.13 12.6 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EER26967.1 - 0.00025 21.5 2.5 0.017 15.5 0.1 3.1 3 1 0 3 3 2 1 AAA ATPase domain AAA_29 PF13555.6 EER26967.1 - 0.00049 19.8 0.1 0.22 11.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EER26967.1 - 0.00093 18.8 0.1 0.018 14.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EER26967.1 - 0.0015 19.1 0.0 0.48 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EER26967.1 - 0.0038 17.1 0.0 1 9.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EER26967.1 - 0.0057 16.4 0.5 0.53 10.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EER26967.1 - 0.0077 16.5 0.3 0.069 13.4 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EER26967.1 - 0.014 15.5 0.3 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain Bcr-Abl_Oligo PF09036.10 EER26967.1 - 0.019 14.9 0.3 0.043 13.8 0.3 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain AAA_17 PF13207.6 EER26967.1 - 0.026 14.9 0.4 0.77 10.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EER26967.1 - 0.054 13.1 0.2 0.71 9.4 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain dNK PF01712.19 EER26967.1 - 0.055 13.3 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 EER26967.1 - 0.068 13.3 0.2 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EER26967.1 - 0.07 13.0 0.8 1 9.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EER26967.1 - 0.16 12.5 0.7 0.9 10.0 0.0 2.3 3 0 0 3 3 2 0 AAA domain Shikimate_dh_N PF08501.11 EER26967.1 - 0.17 12.2 0.0 0.7 10.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate dehydrogenase substrate binding domain Zeta_toxin PF06414.12 EER26967.1 - 0.19 11.0 0.4 5.2 6.3 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin TsaE PF02367.17 EER26967.1 - 0.46 10.5 1.9 0.55 10.2 0.1 2.0 3 0 0 3 3 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MFS_1 PF07690.16 EER26968.1 - 1e-34 120.0 21.5 3.3e-34 118.4 21.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.24 EER26969.1 - 2.4e-38 131.7 6.1 4.7e-38 130.8 6.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EER26969.1 - 3.1e-23 82.6 0.0 8.8e-23 81.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EER26969.1 - 3.7e-18 65.5 0.0 6.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EER26969.1 - 1.8e-15 57.4 3.5 1.8e-15 57.4 3.5 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Glucosaminidase PF01832.20 EER26969.1 - 0.014 15.9 0.1 0.049 14.1 0.0 1.9 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase CoA_transf_3 PF02515.17 EER26970.1 - 1.9e-66 224.7 0.0 2.4e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SAM_4 PF18017.1 EER26970.1 - 0.044 13.8 0.0 0.54 10.3 0.0 2.3 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) DUF1275 PF06912.11 EER26971.1 - 3.2e-48 164.2 8.4 4.3e-48 163.8 8.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_4 PF06779.14 EER26971.1 - 0.024 13.9 4.0 0.14 11.4 0.8 2.2 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Fungal_trans_2 PF11951.8 EER26973.1 - 8.2e-44 150.0 0.9 1.6e-43 149.0 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER26973.1 - 0.00034 20.7 5.4 0.0011 19.0 5.4 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 EER26974.1 - 1.3e-48 165.0 0.1 8.9e-27 94.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EER26974.1 - 3.9e-33 115.3 36.0 3.7e-24 85.8 14.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EER26974.1 - 1.9e-09 37.3 2.5 0.0047 16.4 0.1 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EER26974.1 - 3.1e-06 26.8 0.2 0.017 14.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EER26974.1 - 3.6e-06 27.5 0.1 0.04 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EER26974.1 - 1.6e-05 25.5 0.2 0.0053 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EER26974.1 - 3.8e-05 23.7 1.5 0.016 15.0 0.0 3.6 3 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EER26974.1 - 0.0002 21.4 0.0 0.15 12.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EER26974.1 - 0.00026 21.4 0.8 0.074 13.5 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EER26974.1 - 0.00056 19.9 0.1 0.056 13.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 EER26974.1 - 0.0014 18.3 0.1 1.2 8.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EER26974.1 - 0.0021 17.9 0.3 0.31 10.8 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EER26974.1 - 0.0021 17.3 0.5 0.25 10.5 0.1 2.5 2 1 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 EER26974.1 - 0.0023 17.0 0.1 2 7.3 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EER26974.1 - 0.0023 18.2 3.2 0.12 12.7 0.1 3.1 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 EER26974.1 - 0.0028 16.8 0.0 0.12 11.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 EER26974.1 - 0.0029 17.2 0.1 0.31 10.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_19 PF13245.6 EER26974.1 - 0.0053 17.1 0.0 0.32 11.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EER26974.1 - 0.0062 16.3 0.3 0.1 12.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EER26974.1 - 0.012 15.2 0.0 0.52 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EER26974.1 - 0.013 15.7 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EER26974.1 - 0.023 14.7 0.4 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 EER26974.1 - 0.028 14.8 0.2 7.8 6.9 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Viral_helicase1 PF01443.18 EER26974.1 - 0.029 14.1 0.2 0.66 9.7 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ABC_ATPase PF09818.9 EER26974.1 - 0.03 13.1 1.7 0.32 9.7 0.0 2.8 3 1 0 3 3 3 0 Predicted ATPase of the ABC class Rad17 PF03215.15 EER26974.1 - 0.037 13.9 4.9 0.15 12.0 0.2 3.0 4 0 0 4 4 3 0 Rad17 P-loop domain AAA_24 PF13479.6 EER26974.1 - 0.05 13.3 0.5 4.5 7.0 0.2 2.6 2 1 1 3 3 3 0 AAA domain DUF815 PF05673.13 EER26974.1 - 0.053 12.7 0.0 5.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.9 EER26974.1 - 0.054 12.4 0.2 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 EER26974.1 - 0.097 12.6 3.9 4.3 7.2 0.3 2.8 3 0 0 3 3 2 0 NTPase DUF87 PF01935.17 EER26974.1 - 0.098 12.7 1.2 0.29 11.2 0.1 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Sigma54_activat PF00158.26 EER26974.1 - 0.1 12.3 0.0 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EER26974.1 - 0.11 12.4 0.0 0.97 9.3 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EER26974.1 - 0.13 12.8 0.2 6.1 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EER26974.1 - 0.22 11.1 0.0 0.42 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EER26974.1 - 0.38 10.3 3.6 0.51 9.9 0.2 2.4 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EER26974.1 - 0.62 10.0 2.4 2.7 7.9 0.2 2.8 2 0 0 2 2 2 0 NACHT domain Condensation PF00668.20 EER26975.1 - 0 1290.3 0.0 7.4e-58 196.3 0.0 11.0 10 2 0 10 10 10 9 Condensation domain AMP-binding PF00501.28 EER26975.1 - 0 1278.8 0.0 5e-80 269.2 0.0 5.4 5 0 0 5 5 5 5 AMP-binding enzyme PP-binding PF00550.25 EER26975.1 - 2.4e-93 306.5 5.2 4e-13 49.5 0.1 8.8 8 0 0 8 8 8 8 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EER26975.1 - 2e-11 44.7 0.1 0.2 12.7 0.0 6.1 6 0 0 6 6 6 2 AMP-binding enzyme C-terminal domain Transferase PF02458.15 EER26975.1 - 6.1e-09 35.0 0.0 0.024 13.3 0.0 5.1 5 0 0 5 5 5 3 Transferase family DUF1018 PF06252.12 EER26975.1 - 0.1 13.6 0.3 0.73 10.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) DUF5122 PF17164.4 EER26975.1 - 1.2 9.5 5.3 14 6.1 0.0 4.2 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller BCIP PF13862.6 EER26977.1 - 6.2e-72 241.7 0.2 8.1e-72 241.3 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Sad1_UNC PF07738.13 EER26979.1 - 4.8e-16 59.0 0.0 3.9e-07 30.2 0.1 2.5 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal WD40 PF00400.32 EER26980.1 - 3.3e-29 100.5 11.7 4.7e-06 27.2 0.6 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 EER26980.1 - 1.5e-08 33.8 0.2 0.17 10.5 0.1 4.9 4 1 1 5 5 5 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EER26980.1 - 2e-05 24.8 0.0 0.17 12.2 0.0 4.5 3 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CENP-F_leu_zip PF10473.9 EER26980.1 - 0.0092 16.0 7.1 0.015 15.3 7.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EzrA PF06160.12 EER26980.1 - 0.024 12.8 3.0 0.036 12.3 3.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APG6_N PF17675.1 EER26980.1 - 0.047 14.2 1.3 0.094 13.2 1.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 EER26980.1 - 1.7 8.7 4.2 4.5 7.3 2.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 EER26980.1 - 4.7 7.5 5.6 12 6.2 3.9 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Peptidase_S8 PF00082.22 EER26981.1 - 8.7e-29 100.7 12.5 5.2e-28 98.2 12.5 1.9 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER26981.1 - 1e-17 64.6 0.0 1.7e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Kinesin PF00225.23 EER26982.1 - 1e-91 307.3 0.0 1e-91 307.3 0.0 3.0 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EER26982.1 - 3.1e-19 69.4 0.0 7.8e-16 58.3 0.0 3.4 2 0 0 2 2 2 2 Microtubule binding Mga PF05043.13 EER26982.1 - 5.6 7.6 7.2 0.81 10.3 0.7 3.0 3 0 0 3 3 3 0 Mga helix-turn-helix domain Glycos_transf_1 PF00534.20 EER26983.1 - 2.3e-33 115.1 0.0 1.2e-20 73.7 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EER26983.1 - 5.7e-16 59.0 1.0 8.4e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EER26983.1 - 1.9e-13 51.0 0.0 5.2e-13 49.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EER26983.1 - 6.4e-06 26.7 10.1 2.3e-05 24.9 10.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EER26983.1 - 0.0012 19.1 0.0 0.0026 18.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_5 PF16994.5 EER26983.1 - 0.01 15.5 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl-transferase family 4 YTV PF07639.11 EER26984.1 - 0.13 12.3 0.9 0.37 10.9 0.9 1.7 1 0 0 1 1 1 0 YTV ERCC4 PF02732.15 EER26985.1 - 2e-36 125.5 0.1 4.7e-35 121.1 0.0 2.3 2 0 0 2 2 2 1 ERCC4 domain Cwf_Cwc_15 PF04889.12 EER26985.1 - 0.058 13.1 12.6 0.013 15.2 9.1 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RR_TM4-6 PF06459.12 EER26985.1 - 0.22 11.3 7.9 0.34 10.7 7.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Phage_Gp23 PF10669.9 EER26985.1 - 0.83 10.0 7.7 1.7 9.0 7.7 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MFS_1 PF07690.16 EER26986.1 - 1.6e-18 66.8 16.0 1.6e-18 66.8 16.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EER26986.1 - 9.7e-08 31.8 0.7 9.7e-08 31.8 0.7 1.6 2 0 0 2 2 2 1 Nodulin-like IPK PF03770.16 EER26987.1 - 3.2e-58 196.9 0.0 5.3e-58 196.1 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 EER26987.1 - 0.078 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 NMT1 PF09084.11 EER26988.1 - 1.1e-78 264.1 0.0 1.3e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EER26988.1 - 9.9e-06 25.4 0.0 0.33 10.6 0.0 3.7 3 1 1 4 4 4 2 NMT1-like family PBP_like PF12727.7 EER26988.1 - 0.13 11.3 0.0 1 8.4 0.0 2.1 1 1 1 2 2 2 0 PBP superfamily domain LRR_4 PF12799.7 EER26989.1 - 3.8e-29 100.3 48.1 2.7e-06 27.6 0.1 8.1 6 1 2 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EER26989.1 - 2.9e-23 81.4 45.3 1.1e-07 31.4 1.1 7.2 5 2 1 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 EER26989.1 - 3.4e-10 39.7 7.2 0.00047 19.7 0.4 4.0 3 1 1 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EER26989.1 - 8.7e-07 28.5 36.7 0.6 10.3 0.1 11.3 12 0 0 12 12 12 5 Leucine Rich repeat Syntaxin-18_N PF10496.9 EER26989.1 - 0.051 13.8 0.1 7.5 6.9 0.0 3.6 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus LRR_1 PF00560.33 EER26989.1 - 1.3 9.8 43.5 10 7.2 0.3 12.2 11 2 0 11 11 11 0 Leucine Rich Repeat Pro-MCH PF05824.12 EER26990.1 - 0.076 12.9 0.1 0.3 11.1 0.1 2.0 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) Clathrin PF00637.20 EER26991.1 - 6.7e-21 74.7 1.2 6.3e-19 68.3 0.8 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 EER26991.1 - 3.2e-19 68.9 1.0 9.2e-19 67.4 1.0 1.8 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EER26991.1 - 2e-08 34.1 7.2 3.8e-08 33.2 7.2 1.5 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EER26991.1 - 2.1e-05 24.2 6.8 4.6e-05 23.2 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER26991.1 - 0.00016 21.5 6.1 0.00034 20.5 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EER26991.1 - 0.0071 16.7 6.9 0.014 15.7 6.9 1.5 1 0 0 1 1 1 1 Ring finger domain TPR_11 PF13414.6 EER26991.1 - 0.013 15.2 0.2 0.045 13.4 0.2 2.0 1 0 0 1 1 1 0 TPR repeat HPS3_N PF14761.6 EER26991.1 - 0.018 14.6 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 WD40_like PF17005.5 EER26991.1 - 0.02 14.3 0.4 0.059 12.7 0.1 1.8 3 0 0 3 3 3 0 WD40-like domain TPR_14 PF13428.6 EER26991.1 - 0.029 15.2 0.0 2.1 9.4 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 EER26991.1 - 0.038 14.3 4.6 0.076 13.3 4.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_2 PF07719.17 EER26991.1 - 0.085 13.0 0.1 0.54 10.5 0.1 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-ANAPC11 PF12861.7 EER26991.1 - 0.31 11.1 2.2 0.78 9.8 2.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EER26991.1 - 0.54 10.2 6.5 1 9.3 6.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER26991.1 - 0.82 9.7 8.0 1.9 8.6 8.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger TPR_12 PF13424.6 EER26991.1 - 1.8 8.9 7.3 0.42 10.9 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat RAD51_interact PF15696.5 EER26992.1 - 0.085 13.0 1.6 0.28 11.3 0.1 2.6 3 0 0 3 3 3 0 RAD51 interacting motif Polysacc_deac_1 PF01522.21 EER26993.1 - 2.7e-28 98.4 0.0 5.9e-28 97.2 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EER26993.1 - 6.2e-09 36.2 42.9 0.00039 20.8 19.0 2.6 2 0 0 2 2 2 2 Chitin recognition protein RTP1_C1 PF10363.9 EER26994.1 - 1.3e-31 109.1 1.4 6e-31 106.9 0.1 3.0 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EER26994.1 - 1.5e-09 37.4 0.0 2.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 DBR1 PF05011.13 EER26995.1 - 9.5e-46 155.7 0.9 1.9e-45 154.7 0.0 2.0 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EER26995.1 - 1.5e-06 28.9 1.1 3.1e-06 27.8 1.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GRP PF07172.11 EER26995.1 - 1.4 9.6 17.4 3.4 8.4 17.4 1.6 1 0 0 1 1 1 0 Glycine rich protein family zf-ZPR1 PF03367.13 EER26996.1 - 2.2e-109 362.4 0.0 7.3e-55 185.2 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain DUF4028 PF13220.6 EER26996.1 - 0.072 12.9 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4028) zinc-ribbons_6 PF07191.12 EER26996.1 - 0.36 10.9 3.1 1.6 8.7 0.4 2.4 2 1 0 2 2 2 0 zinc-ribbons Pro_isomerase PF00160.21 EER26997.1 - 7.6e-36 123.8 0.0 5.1e-35 121.1 0.0 1.9 1 1 1 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 EER26998.1 - 2.2e-13 50.8 0.0 7.9e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Fer2_3 PF13085.6 EER26999.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain tRNA_int_end_N2 PF12928.7 EER27000.1 - 2e-27 95.1 0.0 3.7e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EER27000.1 - 0.0078 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1_POZ PF03931.15 EER27001.1 - 8e-09 35.5 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain adh_short_C2 PF13561.6 EER27002.1 - 1.7e-34 119.4 1.8 2.5e-29 102.5 0.4 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER27002.1 - 5.8e-34 117.3 1.7 4.3e-24 85.1 0.4 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EER27002.1 - 3.1e-08 33.7 1.1 1.7e-07 31.3 1.1 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EER27002.1 - 1.2e-05 24.6 0.0 2.3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EER27002.1 - 1.3e-05 24.5 0.1 0.015 14.5 0.1 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Epimerase PF01370.21 EER27002.1 - 0.00022 20.8 0.2 0.003 17.0 0.2 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EER27002.1 - 0.016 15.1 3.1 1.8 8.4 0.0 2.5 3 0 0 3 3 3 0 NAD(P)H-binding ADH_zinc_N PF00107.26 EER27002.1 - 0.11 12.5 0.0 0.38 10.7 0.0 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ThiF PF00899.21 EER27003.1 - 3.5e-72 242.7 0.0 5e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EER27003.1 - 1.3e-20 73.7 0.0 3.6e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EER27003.1 - 1.1e-06 28.7 0.9 0.002 18.1 0.0 2.8 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EER27003.1 - 0.0001 22.7 0.1 0.00042 20.7 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.27 EER27003.1 - 0.0058 17.2 0.1 0.83 10.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EER27003.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3192 PF11399.8 EER27003.1 - 0.046 13.7 0.2 0.11 12.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Glt_symporter PF03616.14 EER27003.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter Q_salvage PF10343.9 EER27004.1 - 2.8e-137 456.9 0.1 3.6e-137 456.6 0.1 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF4121 PF13497.6 EER27004.1 - 0.038 13.2 0.5 0.06 12.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Interfer-bind PF09294.10 EER27004.1 - 0.089 13.1 0.1 0.19 12.1 0.1 1.4 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III ORC6 PF05460.13 EER27005.1 - 6.6e-58 196.7 0.0 8.3e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Amidase PF01425.21 EER27006.1 - 1.7e-91 307.5 0.0 2.3e-91 307.1 0.0 1.2 1 0 0 1 1 1 1 Amidase UPF0180 PF03698.13 EER27006.1 - 0.19 11.9 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) DNA_pol_delta_4 PF04081.13 EER27007.1 - 1.8e-36 125.3 0.6 2.6e-36 124.9 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 HrpE PF06188.12 EER27007.1 - 0.011 15.6 1.4 0.016 15.1 1.4 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF3664 PF12406.8 EER27007.1 - 0.017 15.8 2.6 0.034 14.8 2.6 1.5 1 0 0 1 1 1 0 Surface protein TFIIF_alpha PF05793.12 EER27007.1 - 1.4 7.4 6.1 1.8 7.1 6.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CFEM PF05730.11 EER27008.1 - 1.3e-15 57.3 5.3 1.7e-15 56.8 5.3 1.2 1 0 0 1 1 1 1 CFEM domain PT PF04886.12 EER27008.1 - 2e-07 30.5 36.5 4e-06 26.3 36.5 2.9 1 1 0 1 1 1 1 PT repeat Trypan_PARP PF05887.11 EER27008.1 - 0.15 12.1 16.5 0.3 11.1 16.5 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Caveolin PF01146.17 EER27009.1 - 0.003 17.5 1.1 0.004 17.1 1.1 1.1 1 0 0 1 1 1 1 Caveolin Ank_2 PF12796.7 EER27010.1 - 4.9e-09 36.7 0.0 2e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER27010.1 - 1.6e-08 34.9 0.1 0.029 15.0 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER27010.1 - 5.8e-06 26.3 2.5 0.64 10.8 0.1 5.1 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EER27010.1 - 2.7e-05 24.4 0.3 0.75 10.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EER27010.1 - 0.0013 19.0 0.1 0.062 13.6 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Citrate_bind PF16114.5 EER27011.1 - 1.9e-87 291.3 0.1 2.6e-87 290.9 0.1 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EER27011.1 - 9.6e-09 35.1 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 EER27011.1 - 0.011 13.9 0.1 0.016 13.3 0.1 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Citrate_synt PF00285.21 EER27012.1 - 1e-20 74.2 0.0 5.8e-18 65.1 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EER27012.1 - 1.2e-19 70.7 0.1 3.9e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EER27012.1 - 5.9e-16 58.6 0.1 1.1e-15 57.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EER27012.1 - 4.6e-08 32.9 0.1 6.7e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ank_2 PF12796.7 EER27013.1 - 2.4e-38 130.6 0.0 4.7e-10 39.9 0.0 5.3 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER27013.1 - 2.3e-36 123.7 4.7 5.2e-09 36.5 0.0 7.5 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER27013.1 - 6.6e-33 109.1 4.8 0.00015 21.9 0.0 10.5 11 0 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 EER27013.1 - 1.8e-31 107.2 6.2 0.0005 20.4 0.0 8.8 8 1 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EER27013.1 - 4.3e-29 100.2 1.7 2.4e-06 27.7 0.0 7.6 4 2 4 8 8 8 6 Ankyrin repeats (many copies) F-box-like PF12937.7 EER27013.1 - 0.00034 20.4 0.4 0.0013 18.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like GATase_7 PF13537.6 EER27013.1 - 0.043 13.7 0.0 41 4.1 0.0 3.7 4 0 0 4 4 4 0 Glutamine amidotransferase domain RNase_P_Rpp14 PF01900.19 EER27015.1 - 1.7e-38 131.0 0.0 2.2e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family CUE PF02845.16 EER27015.1 - 0.17 11.6 0.0 23 4.8 0.1 2.3 2 0 0 2 2 2 0 CUE domain ATP_bind_1 PF03029.17 EER27016.1 - 4.5e-78 262.4 0.0 5.9e-78 262.0 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 EER27016.1 - 0.00054 19.9 0.0 0.48 10.3 0.0 2.3 1 1 1 2 2 2 2 AAA domain MeaB PF03308.16 EER27016.1 - 0.0013 17.8 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EER27016.1 - 0.0013 18.8 0.0 0.01 15.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.7 EER27016.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain KTI12 PF08433.10 EER27016.1 - 0.015 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 EER27016.1 - 0.027 14.9 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EER27016.1 - 0.03 14.9 1.3 0.23 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EER27016.1 - 0.038 14.4 0.1 0.13 12.7 0.1 1.9 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 EER27016.1 - 0.044 13.2 0.1 0.099 12.1 0.0 1.6 1 1 1 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_29 PF13555.6 EER27016.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EER27016.1 - 0.051 14.0 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EER27016.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EER27016.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EER27016.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain CLP1_P PF16575.5 EER27016.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EER27016.1 - 0.14 12.3 0.1 0.34 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 EER27017.1 - 2.5e-05 24.9 0.0 0.1 13.5 0.1 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27017.1 - 0.15 12.3 0.0 1.4 9.3 0.0 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain ThiF PF00899.21 EER27018.1 - 4.8e-14 52.3 0.0 3e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 EER27018.1 - 0.0089 16.2 0.0 2.3 8.5 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin-activating enzyme E1 four-helix bundle LtrA PF06772.11 EER27019.1 - 1.1e-25 90.7 17.6 1.1e-25 90.7 17.6 2.0 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) CaATP_NAI PF12515.8 EER27019.1 - 7.2 6.3 5.2 3.8 7.2 0.1 2.8 3 0 0 3 3 3 0 Ca2+-ATPase N terminal autoinhibitory domain GMC_oxred_N PF00732.19 EER27020.1 - 7.8e-64 215.9 0.0 9.6e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EER27020.1 - 9.1e-10 39.2 0.0 1.6e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EER27020.1 - 2.9e-07 29.9 0.0 0.00023 20.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EER27020.1 - 8.9e-06 25.5 0.1 0.026 14.1 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EER27020.1 - 0.00083 18.5 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EER27020.1 - 0.0031 16.8 0.1 0.073 12.3 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER27020.1 - 0.033 12.9 0.0 0.39 9.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 EER27020.1 - 0.037 14.3 0.1 0.088 13.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EER27020.1 - 0.12 11.6 0.2 0.49 9.6 0.0 1.9 2 0 0 2 2 2 0 Thi4 family DUF1180 PF06679.12 EER27021.1 - 7.6 6.9 8.5 0.15 12.5 0.5 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) An_peroxidase PF03098.15 EER27023.1 - 1.5e-43 149.2 0.0 5.1e-30 104.5 0.0 3.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 EER27023.1 - 5.9e-07 28.6 0.0 6.4e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Asp PF00026.23 EER27024.1 - 5.9e-11 42.4 0.0 9.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.10 EER27024.1 - 0.019 14.4 4.6 0.04 13.3 4.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-C3HC4_3 PF13920.6 EER27025.1 - 3.8e-09 36.3 11.7 6.1e-09 35.6 11.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER27027.1 - 0.00027 20.9 1.2 0.00047 20.1 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EER27027.1 - 0.00073 19.3 0.4 0.0012 18.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EER27027.1 - 0.0019 18.1 0.4 0.0033 17.3 0.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-NADH-PPase PF09297.11 EER27027.1 - 0.0025 17.4 1.0 0.0042 16.7 1.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-RING_2 PF13639.6 EER27027.1 - 0.0068 16.7 0.8 0.013 15.8 0.8 1.4 1 0 0 1 1 1 1 Ring finger domain DZR PF12773.7 EER27027.1 - 0.012 15.6 0.4 0.022 14.8 0.4 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_5 PF17121.5 EER27027.1 - 0.041 13.8 0.8 11 6.0 0.1 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EER27027.1 - 0.11 12.7 0.6 0.22 11.7 0.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zinc_ribbon_9 PF14369.6 EER27027.1 - 0.13 12.6 0.3 0.22 11.8 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon zf-C3HC4_2 PF13923.6 EER27027.1 - 0.16 11.9 2.3 0.83 9.5 2.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) XAP5 PF04921.14 EER27028.1 - 3.8e-88 295.5 0.0 5.7e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 EER27028.1 - 0.0011 19.4 2.0 0.0019 18.6 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Fip1 PF05182.13 EER27029.1 - 1.7e-20 72.3 2.3 2.9e-20 71.5 2.3 1.4 1 0 0 1 1 1 1 Fip1 motif Cpn10 PF00166.21 EER27030.1 - 1e-28 99.2 0.0 1.1e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Nucleoporin_FG PF13634.6 EER27032.1 - 3.8e-06 27.6 71.1 0.00074 20.3 25.6 3.5 2 1 2 4 4 4 3 Nucleoporin FG repeat region DUF1664 PF07889.12 EER27032.1 - 0.023 14.7 0.3 0.85 9.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ISG65-75 PF11727.8 EER27032.1 - 0.17 11.1 0.1 3.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein WD40 PF00400.32 EER27033.1 - 0.00075 20.3 12.0 11 7.1 0.2 6.8 6 2 0 6 6 6 2 WD domain, G-beta repeat Lactonase PF10282.9 EER27033.1 - 0.0072 15.6 0.0 0.021 14.1 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller ANAPC4_WD40 PF12894.7 EER27033.1 - 0.036 14.3 0.0 6.1 7.2 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Lipoprotein_3 PF00938.17 EER27034.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein HAD_2 PF13419.6 EER27035.1 - 7.1e-17 62.1 0.0 1e-16 61.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EER27035.1 - 2.2e-09 37.9 0.0 3.6e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER27035.1 - 0.00024 21.1 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like TPR_1 PF00515.28 EER27036.1 - 3.9e-06 26.4 1.9 0.039 13.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EER27036.1 - 0.00015 21.6 2.3 0.83 9.9 0.0 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EER27036.1 - 0.0026 18.0 0.8 0.018 15.3 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER27036.1 - 0.014 15.0 0.7 0.043 13.5 0.1 2.1 2 0 0 2 2 2 0 TPR repeat DUF3112 PF11309.8 EER27037.1 - 1.9e-13 50.4 0.6 1.4e-09 37.7 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3112) Phage_holin_3_6 PF07332.11 EER27037.1 - 0.07 13.2 7.4 0.036 14.1 2.5 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2070 PF09843.9 EER27037.1 - 0.95 7.7 4.0 1.3 7.3 4.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Metallophos PF00149.28 EER27038.1 - 1e-30 107.8 0.1 1.2e-30 107.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EER27038.1 - 0.062 12.9 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF3908 PF13048.6 EER27039.1 - 0.12 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3908) Rib_5-P_isom_A PF06026.14 EER27040.1 - 7.1e-44 149.4 0.0 1.3e-43 148.6 0.0 1.4 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EER27040.1 - 0.03 14.3 0.0 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain PI31_Prot_N PF11566.8 EER27041.1 - 1.3e-50 171.3 0.0 1.7e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EER27041.1 - 1e-18 68.3 19.2 1e-18 68.3 19.2 3.3 4 0 0 4 4 4 1 PI31 proteasome regulator DUF2183 PF09949.9 EER27042.1 - 7.9e-32 109.5 0.0 6.3e-31 106.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EER27042.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF2064 PF09837.9 EER27043.1 - 5.4e-14 52.1 0.0 9.7e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) HTH_23 PF13384.6 EER27043.1 - 0.074 12.9 0.1 0.28 11.0 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain DUF3641 PF12345.8 EER27044.1 - 1.2e-51 174.3 0.0 2.1e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 EER27044.1 - 2.8e-09 37.6 0.2 2.3e-08 34.6 0.2 2.2 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 EER27044.1 - 2.2e-05 24.7 0.2 4.2e-05 23.8 0.2 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EER27044.1 - 0.018 15.2 0.7 0.036 14.2 0.4 1.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain SPASM PF13186.6 EER27044.1 - 0.072 13.6 0.2 0.22 12.1 0.2 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain Cytochrom_C550 PF14495.6 EER27044.1 - 0.1 12.3 1.1 0.23 11.2 0.9 1.7 1 1 0 1 1 1 0 Cytochrome c-550 domain p450 PF00067.22 EER27045.1 - 6.7e-14 51.5 0.0 3.4e-13 49.2 0.0 2.0 3 0 0 3 3 3 1 Cytochrome P450 FA_hydroxylase PF04116.13 EER27046.1 - 1e-13 51.8 9.8 1e-13 51.8 9.8 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UvdE PF03851.14 EER27047.1 - 1.7e-111 371.9 0.0 2.2e-111 371.5 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Cu_amine_oxid PF01179.20 EER27048.1 - 3.7e-151 503.7 0.0 4.6e-151 503.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EER27048.1 - 3.7e-08 33.5 0.2 4.7e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EER27048.1 - 0.0048 17.3 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Aldedh PF00171.22 EER27049.1 - 3.6e-163 543.4 0.7 4.1e-163 543.2 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PSII_Pbs31 PF18240.1 EER27050.1 - 0.033 14.6 0.1 0.056 13.9 0.1 1.3 1 0 0 1 1 1 0 Photosystem II Psb31 protein Amino_oxidase PF01593.24 EER27051.1 - 4.3e-45 154.8 0.1 5.1e-44 151.3 0.1 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EER27051.1 - 1.1e-14 54.4 0.1 2.3e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EER27051.1 - 6.2e-06 25.6 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER27051.1 - 1.5e-05 25.5 0.3 3.9e-05 24.1 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER27051.1 - 0.00022 20.1 0.5 0.00035 19.4 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EER27051.1 - 0.00054 19.2 0.4 0.00084 18.5 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EER27051.1 - 0.00095 18.3 0.1 0.0014 17.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EER27051.1 - 0.0013 18.0 0.4 0.0021 17.3 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EER27051.1 - 0.0022 17.7 3.7 0.0095 15.6 3.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EER27051.1 - 0.0056 16.0 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EER27051.1 - 0.011 15.0 0.2 0.017 14.4 0.2 1.2 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EER27051.1 - 0.011 15.1 0.1 0.028 13.8 0.1 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EER27051.1 - 0.044 13.7 0.1 0.097 12.5 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EER27051.1 - 0.098 11.7 0.2 0.2 10.7 0.2 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EER27051.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EER27051.1 - 0.18 11.8 1.3 2.4 8.1 0.4 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EER27051.1 - 0.2 10.8 1.0 0.38 10.0 1.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Homeodomain PF00046.29 EER27052.1 - 7e-14 51.4 2.1 7e-14 51.4 2.1 2.2 2 0 0 2 2 2 1 Homeodomain NAD_binding_10 PF13460.6 EER27053.1 - 4.2e-07 30.0 0.0 3.9e-05 23.6 0.0 2.5 2 1 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 EER27053.1 - 1.3e-06 28.2 0.0 5.7e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family Shikimate_DH PF01488.20 EER27053.1 - 0.039 14.0 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box PF00646.33 EER27054.1 - 0.016 15.1 0.8 0.17 11.8 0.0 2.9 3 0 0 3 3 3 0 F-box domain DUF4722 PF15849.5 EER27054.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4722) Methyltransf_11 PF08241.12 EER27056.1 - 6.3e-20 71.6 0.1 7.4e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER27056.1 - 3.4e-19 69.3 0.2 4e-19 69.1 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER27056.1 - 2e-16 60.2 0.0 2.3e-16 60.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER27056.1 - 1.3e-14 54.4 0.0 1.5e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER27056.1 - 9.3e-14 52.0 0.1 1.1e-13 51.8 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EER27056.1 - 3.5e-12 46.2 0.0 4.2e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EER27056.1 - 4.4e-09 36.1 0.0 7e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EER27056.1 - 5.2e-08 32.5 0.0 6.3e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EER27056.1 - 1.2e-06 28.2 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 EER27056.1 - 6.7e-05 22.9 0.2 7.3e-05 22.7 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EER27056.1 - 9.4e-05 22.2 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.19 EER27056.1 - 0.00022 21.0 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 EER27056.1 - 0.0003 20.3 0.0 0.00089 18.8 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PrmA PF06325.13 EER27056.1 - 0.00074 19.0 0.1 0.00093 18.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EER27056.1 - 0.00076 19.5 0.1 0.0008 19.4 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.10 EER27056.1 - 0.0012 18.4 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 EER27056.1 - 0.0013 17.8 0.0 0.0016 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.12 EER27056.1 - 0.0013 18.3 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.11 EER27056.1 - 0.003 17.2 0.0 0.0034 17.0 0.0 1.0 1 0 0 1 1 1 1 Nodulation protein S (NodS) TrmK PF04816.12 EER27056.1 - 0.027 14.0 0.4 0.031 13.8 0.4 1.1 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase TehB PF03848.14 EER27056.1 - 0.028 13.8 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltr_RsmB-F PF01189.17 EER27056.1 - 0.035 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F TPMT PF05724.11 EER27056.1 - 0.099 12.3 0.0 0.099 12.3 0.0 1.3 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Cons_hypoth95 PF03602.15 EER27056.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Ank_2 PF12796.7 EER27057.1 - 2e-23 82.8 0.1 1e-10 42.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EER27057.1 - 1.2e-19 69.8 1.6 9.6e-07 29.0 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EER27057.1 - 4.4e-18 65.4 0.3 4.6e-09 36.7 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER27057.1 - 5e-17 60.2 0.4 7.6e-06 25.9 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EER27057.1 - 2.5e-15 56.3 0.4 4.8e-08 33.1 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 EER27057.1 - 2.1e-10 40.3 0.0 4.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 EER27057.1 - 5.5e-09 36.2 0.1 1.1e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EER27057.1 - 4.6e-06 27.1 0.0 1.7e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EER27057.1 - 0.024 14.9 0.3 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EER27057.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DSPn PF14671.6 EER27058.1 - 6.4e-40 136.9 0.0 9.5e-38 129.8 0.0 2.4 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EER27058.1 - 1.8e-16 60.2 0.0 4e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EER27058.1 - 2.8e-05 23.8 0.0 4.3e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pcc1 PF09341.10 EER27059.1 - 5.1e-16 58.6 0.1 5.6e-16 58.4 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 HATPase_c PF02518.26 EER27060.1 - 2.4e-07 31.3 0.0 5.4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EER27060.1 - 9.1e-06 25.8 0.0 4.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain Translin PF01997.16 EER27061.1 - 5e-52 176.9 0.1 5.8e-52 176.7 0.1 1.0 1 0 0 1 1 1 1 Translin family CLPTM1 PF05602.12 EER27061.1 - 0.012 14.7 0.2 0.28 10.2 0.0 2.0 2 0 0 2 2 2 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) GMP_synt_C PF00958.22 EER27061.1 - 0.023 14.8 0.1 0.38 10.8 0.0 2.3 2 0 0 2 2 2 0 GMP synthase C terminal domain HR1 PF02185.16 EER27061.1 - 0.038 14.1 0.2 0.072 13.2 0.2 1.4 1 0 0 1 1 1 0 Hr1 repeat Rx_N PF18052.1 EER27061.1 - 0.088 13.1 0.7 17 5.7 0.7 3.3 3 1 0 3 3 3 0 Rx N-terminal domain GSHPx PF00255.19 EER27062.1 - 7.6e-38 128.4 0.0 9.7e-38 128.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EER27062.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EER27062.1 - 0.15 11.7 0.1 0.23 11.2 0.1 1.5 1 1 0 1 1 1 0 Redoxin Foamy_BEL PF03274.14 EER27062.1 - 0.18 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein Ribosomal_L22e PF01776.17 EER27063.1 - 4.8e-49 165.3 0.2 5.9e-49 165.0 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Peptidase_S8 PF00082.22 EER27065.1 - 2.4e-30 105.9 9.2 7.1e-30 104.3 9.2 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER27065.1 - 2e-13 50.8 0.0 3.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Hydrolase_6 PF13344.6 EER27066.1 - 4.6e-23 81.2 0.0 8.3e-23 80.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER27066.1 - 2.1e-12 46.9 0.0 2.1e-11 43.7 0.0 2.7 3 1 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 EER27066.1 - 0.014 15.7 0.0 8.1 6.7 0.0 2.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase CFEM PF05730.11 EER27067.1 - 0.0022 18.0 4.6 0.0045 17.1 4.6 1.5 1 0 0 1 1 1 1 CFEM domain Pmp3 PF01679.17 EER27068.1 - 6.5e-25 87.1 9.0 7.3e-25 86.9 9.0 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MMR_HSR1_C PF08438.10 EER27070.1 - 4.4e-36 123.8 0.0 8.9e-36 122.9 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EER27070.1 - 1.3e-12 47.8 0.0 3.9e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EER27070.1 - 0.044 13.6 0.0 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AIG1 PF04548.16 EER27070.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 EER27070.1 - 0.11 13.0 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EER27070.1 - 0.14 12.1 0.1 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EER27070.1 - 0.16 11.5 0.3 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B SET PF00856.28 EER27071.1 - 0.0021 18.5 0.0 0.0042 17.5 0.0 1.7 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.18 EER27072.1 - 4.1e-33 114.5 0.8 6.8e-33 113.8 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER27072.1 - 2.1e-08 34.2 14.9 4.3e-08 33.1 14.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.21 EER27073.1 - 5.1e-155 515.5 0.0 6.8e-155 515.1 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EER27073.1 - 1.2e-45 155.3 0.0 2e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EER27073.1 - 2.7e-12 46.7 0.0 5.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EER27073.1 - 9.6e-06 25.0 0.0 0.00062 19.1 0.0 2.1 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EER27073.1 - 0.0057 15.6 0.1 0.0089 15.0 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Beta_elim_lyase PF01212.21 EER27073.1 - 0.0071 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase zf-RING_13 PF17977.1 EER27073.1 - 0.095 12.8 0.1 0.27 11.4 0.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Spermine_synth PF01564.17 EER27074.1 - 1.4e-69 233.3 0.0 1.8e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EER27074.1 - 1.9e-23 82.1 0.0 3.5e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EER27074.1 - 5.7e-05 23.8 0.0 0.00011 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER27074.1 - 0.0013 19.4 0.1 0.0034 18.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EER27074.1 - 0.0072 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EER27074.1 - 0.065 12.5 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_30 PF05430.11 EER27074.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase bZIP_1 PF00170.21 EER27075.1 - 1e-05 25.6 17.1 0.00022 21.2 11.8 2.4 1 1 1 2 2 2 2 bZIP transcription factor DUF812 PF05667.11 EER27075.1 - 0.00067 18.7 1.1 0.00074 18.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Nup54 PF13874.6 EER27075.1 - 0.0011 19.1 5.9 0.0021 18.1 5.9 1.6 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 PspA_IM30 PF04012.12 EER27075.1 - 0.0014 18.3 1.7 0.002 17.7 1.7 1.3 1 0 0 1 1 1 1 PspA/IM30 family FAM92 PF06730.11 EER27075.1 - 0.0042 16.5 0.4 0.0061 16.0 0.4 1.2 1 0 0 1 1 1 1 FAM92 protein TSC22 PF01166.18 EER27075.1 - 0.01 16.2 2.5 0.017 15.4 0.3 2.1 1 1 1 2 2 2 0 TSC-22/dip/bun family SlyX PF04102.12 EER27075.1 - 0.017 15.7 4.6 0.017 15.7 3.2 1.7 1 1 0 1 1 1 0 SlyX Exonuc_VII_L PF02601.15 EER27075.1 - 0.021 14.4 2.8 0.023 14.3 2.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 EER27075.1 - 0.029 14.8 0.2 0.047 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 bZIP_Maf PF03131.17 EER27075.1 - 0.034 14.6 9.9 0.077 13.5 9.9 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor Vac_Fusion PF02346.16 EER27075.1 - 0.045 13.4 0.6 0.088 12.4 0.6 1.6 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 bZIP_2 PF07716.15 EER27075.1 - 0.049 13.7 18.8 0.15 12.2 13.7 2.3 1 1 1 2 2 2 0 Basic region leucine zipper GAS PF13851.6 EER27075.1 - 0.051 12.9 5.7 0.071 12.5 5.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Transcrip_act PF04949.13 EER27075.1 - 0.058 13.3 3.4 0.079 12.8 2.6 1.4 1 1 0 1 1 1 0 Transcriptional activator DUF4404 PF14357.6 EER27075.1 - 0.077 13.6 1.3 0.14 12.8 1.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) DUF3631 PF12307.8 EER27075.1 - 0.13 12.5 5.0 0.2 11.9 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3631) ABC_tran_CTD PF16326.5 EER27075.1 - 0.14 12.4 3.2 0.3 11.4 3.2 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain CLZ PF16526.5 EER27075.1 - 0.14 12.5 4.8 0.53 10.7 3.7 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF1043 PF06295.12 EER27075.1 - 0.17 11.9 1.5 0.25 11.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) FapA PF03961.13 EER27075.1 - 0.2 10.2 1.6 0.25 9.9 1.6 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Csm1_N PF18504.1 EER27075.1 - 0.35 11.2 3.4 0.5 10.7 1.6 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain GvpL_GvpF PF06386.11 EER27075.1 - 0.42 10.5 11.0 2.4 8.0 11.0 1.9 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF SHE3 PF17078.5 EER27075.1 - 0.43 10.2 7.3 0.86 9.3 7.3 1.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DivIC PF04977.15 EER27075.1 - 0.45 10.3 3.4 0.32 10.8 0.8 1.9 1 1 1 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.9 EER27075.1 - 0.53 10.5 12.1 0.72 10.1 12.1 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 APG6_N PF17675.1 EER27075.1 - 0.71 10.4 9.2 1 9.9 9.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 EER27075.1 - 1.3 9.4 6.4 0.41 11.1 2.6 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ZapB PF06005.12 EER27075.1 - 1.5 9.3 10.7 0.13 12.7 5.5 1.8 1 1 1 2 2 2 0 Cell division protein ZapB Uso1_p115_C PF04871.13 EER27075.1 - 2.3 8.6 6.8 2 8.8 4.1 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region G-alpha PF00503.20 EER27076.1 - 6.5e-109 364.3 0.1 7.9e-109 364.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EER27076.1 - 6.6e-14 51.7 0.7 2.7e-09 36.7 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EER27076.1 - 2.3e-07 30.4 0.1 0.0031 16.9 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EER27076.1 - 0.0011 19.1 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Roc PF08477.13 EER27076.1 - 0.0053 17.0 0.0 0.94 9.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EER27076.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 EER27076.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EER27076.1 - 0.11 11.8 0.0 0.67 9.3 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF1713 PF08213.11 EER27077.1 - 5e-11 42.3 19.2 5e-11 42.3 19.2 2.4 3 0 0 3 3 3 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 EER27077.1 - 0.005 17.6 0.1 0.025 15.3 0.0 2.3 2 0 0 2 2 2 1 Mitochondrial protein Pet20 ATP-synt_C PF00137.21 EER27078.1 - 7.7e-34 115.8 32.2 6.5e-21 74.4 14.8 2.4 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.26 EER27079.1 - 1.2e-17 63.4 1.3 1.2e-17 63.4 1.3 3.0 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PRP1_N PF06424.12 EER27079.1 - 2 8.8 16.0 8.3 6.8 11.4 2.4 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal UcrQ PF02939.16 EER27080.1 - 6.1e-35 119.0 0.2 7e-35 118.8 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.25 EER27081.1 - 8.1e-25 87.9 8.0 1.8e-24 86.7 8.0 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EER27081.1 - 0.0018 17.4 4.4 0.0025 16.9 4.4 1.3 1 0 0 1 1 1 1 SigmaW regulon antibacterial Methyltransf_34 PF11312.8 EER27083.1 - 1.1e-93 313.9 0.0 1.7e-93 313.2 0.0 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF202 PF02656.15 EER27085.1 - 5e-22 78.1 0.2 5e-22 78.1 0.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) FNIP_N PF14636.6 EER27085.1 - 0.39 11.7 6.1 0.79 10.7 6.1 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus PTPA PF03095.15 EER27086.1 - 3.9e-107 358.2 0.0 4.6e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ank_2 PF12796.7 EER27087.1 - 6.9e-66 218.9 7.3 5.7e-13 49.3 0.0 7.6 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EER27087.1 - 1.1e-37 127.6 16.7 4.9e-07 29.9 0.0 9.3 5 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER27087.1 - 1.9e-37 123.0 9.4 0.00094 19.5 0.0 12.6 13 0 0 13 13 13 7 Ankyrin repeat Ank_4 PF13637.6 EER27087.1 - 2.1e-36 123.8 9.7 1.5e-05 25.5 0.0 10.1 5 2 8 13 13 13 9 Ankyrin repeats (many copies) Ank PF00023.30 EER27087.1 - 1e-29 101.7 13.6 0.00015 22.1 0.0 12.6 11 2 1 12 12 12 8 Ankyrin repeat HA1 PF18239.1 EER27087.1 - 0.0025 17.6 0.0 0.0077 16.1 0.0 1.8 1 0 0 1 1 1 1 Hemagglutinin I DUF1843 PF08898.10 EER27087.1 - 0.14 12.6 0.1 3.5 8.2 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) GDPD_2 PF13653.6 EER27087.1 - 0.95 10.0 6.3 1.8 9.2 0.1 4.2 5 0 0 5 5 5 0 Glycerophosphoryl diester phosphodiesterase family Fer2_3 PF13085.6 EER27088.1 - 1.4e-32 111.9 0.0 2.2e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EER27088.1 - 9.4e-09 35.7 6.1 9.4e-09 35.7 6.1 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EER27088.1 - 1.5e-07 31.7 8.6 1.5e-07 31.7 8.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EER27088.1 - 2.9e-07 30.5 3.3 2.9e-07 30.5 3.3 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EER27088.1 - 0.0069 16.9 6.6 0.0069 16.9 6.6 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EER27088.1 - 0.0079 16.1 0.4 0.0079 16.1 0.4 2.5 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 EER27088.1 - 0.63 10.3 14.2 0.22 11.7 8.8 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EER27088.1 - 1.3 9.2 7.2 0.88 9.8 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain F_bP_aldolase PF01116.20 EER27089.1 - 4.6e-84 282.2 0.0 5.1e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Acetyltransf_1 PF00583.25 EER27090.1 - 1.4e-07 31.7 0.0 2.2e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER27090.1 - 8.4e-06 25.7 0.0 2.6e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER27090.1 - 6.8e-05 23.2 0.0 9.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EER27090.1 - 0.05 13.6 0.0 0.21 11.6 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase RTA1 PF04479.13 EER27091.1 - 1.3e-74 250.3 1.2 1.9e-74 249.8 1.2 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF202 PF02656.15 EER27091.1 - 0.89 10.0 5.0 0.32 11.5 0.3 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF308 PF03729.13 EER27091.1 - 1.5 9.2 13.0 0.098 13.0 1.9 3.3 3 1 0 3 3 3 0 Short repeat of unknown function (DUF308) Evr1_Alr PF04777.13 EER27092.1 - 8.9e-28 96.7 0.2 1.2e-27 96.2 0.2 1.2 1 0 0 1 1 1 1 Erv1 / Alr family DUF4553 PF15090.6 EER27092.1 - 0.047 12.7 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) APOBEC4 PF18775.1 EER27092.1 - 0.058 13.6 0.3 0.13 12.5 0.2 1.6 1 1 0 1 1 1 0 APOBEC4 MyTH4 PF00784.17 EER27092.1 - 0.13 12.8 0.2 0.25 11.8 0.2 1.6 1 1 0 1 1 1 0 MyTH4 domain APOBEC1 PF18769.1 EER27092.1 - 0.16 12.3 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 APOBEC1 zf-LYAR PF08790.11 EER27093.1 - 6.4e-14 51.5 3.4 6.4e-14 51.5 3.4 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Phosphoprotein PF00922.17 EER27093.1 - 0.061 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein R3H PF01424.22 EER27094.1 - 5.5e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 EER27094.1 - 9e-06 25.6 82.4 8.3e-05 22.6 14.6 14.6 13 4 1 14 14 14 7 NF-X1 type zinc finger SDA1 PF05285.12 EER27094.1 - 0.44 9.9 13.5 0.78 9.1 13.5 1.3 1 0 0 1 1 1 0 SDA1 G_glu_transpept PF01019.21 EER27095.1 - 9.4e-172 572.3 0.0 1.1e-171 572.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HhH-GPD PF00730.25 EER27096.1 - 1.3e-06 28.9 0.0 1.6e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Git3 PF11710.8 EER27098.1 - 1.5e-29 103.3 9.2 2.9e-29 102.3 9.2 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EER27098.1 - 3.8e-10 39.7 0.0 1.2e-09 38.1 0.0 1.9 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EER27098.1 - 0.00019 20.9 4.5 0.00035 20.0 4.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 EER27098.1 - 0.0021 17.3 4.3 0.0021 17.3 4.3 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor YcgR_2 PF12945.7 EER27098.1 - 0.099 12.8 0.0 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Flagellar protein YcgR OapA_N PF08525.11 EER27098.1 - 0.18 11.8 1.1 0.47 10.5 0.0 2.4 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif MFS_1 PF07690.16 EER27099.1 - 8.1e-08 31.6 47.7 3.9e-05 22.7 15.5 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.12 EER27099.1 - 0.0016 18.6 3.9 0.0016 18.5 1.1 2.5 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 TRI12 PF06609.13 EER27099.1 - 0.036 12.5 15.5 0.0077 14.7 6.5 2.8 1 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) PBP_N PF17093.5 EER27099.1 - 0.11 12.8 0.1 8.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus MFS_1 PF07690.16 EER27100.1 - 7.5e-51 173.1 32.1 7.5e-51 173.1 32.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER27100.1 - 1.2e-12 47.4 6.0 1.2e-12 47.4 6.0 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EER27100.1 - 1.4e-07 31.2 5.1 1.4e-07 31.2 5.1 2.7 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 EER27100.1 - 0.33 11.4 4.3 0.27 11.7 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) BT1 PF03092.16 EER27100.1 - 0.41 8.8 11.6 0.044 12.0 0.9 2.9 3 1 1 4 4 4 0 BT1 family Methyltransf_23 PF13489.6 EER27101.1 - 1.4e-08 34.8 0.0 7.2e-06 25.9 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EER27101.1 - 0.0025 17.6 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER27101.1 - 0.018 15.8 0.0 0.048 14.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EER27101.1 - 0.027 15.1 0.0 0.06 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EER27101.1 - 0.051 14.3 0.0 0.13 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Amidase PF01425.21 EER27102.1 - 1.7e-70 238.2 0.0 5e-66 223.5 0.1 2.0 1 1 1 2 2 2 2 Amidase fn3_2 PF16893.5 EER27103.1 - 4.1e-38 129.4 0.1 6.8e-38 128.7 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EER27103.1 - 9.2e-25 86.4 0.6 1.7e-24 85.5 0.6 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EER27103.1 - 1.3e-15 57.0 0.0 2.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EER27103.1 - 7.8e-10 39.0 0.0 1.4e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EER27103.1 - 2.4e-05 24.7 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain DUF3006 PF11213.8 EER27103.1 - 0.00014 22.0 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EER27103.1 - 0.0079 16.5 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 1 Fibronectin type III domain ERCC4 PF02732.15 EER27104.1 - 3e-17 63.3 0.0 1.6e-16 60.9 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain Rtt106 PF08512.12 EER27104.1 - 0.019 15.4 0.5 7.9 7.0 0.0 3.1 3 0 0 3 3 3 0 Histone chaperone Rttp106-like DUF4780 PF16012.5 EER27104.1 - 0.057 12.9 0.5 5.1 6.5 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4780) eIF-1a PF01176.19 EER27105.1 - 4.7e-22 77.6 0.0 6.5e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.23 EER27106.1 - 4.4e-29 100.6 0.0 6.6e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EER27106.1 - 0.00028 20.6 0.2 0.0008 19.2 0.2 1.7 1 0 0 1 1 1 1 WH2 motif CorA PF01544.18 EER27107.1 - 8.5e-09 35.1 0.1 1.2e-08 34.6 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SEN1_N PF12726.7 EER27109.1 - 2.5e-205 684.0 0.8 3.5e-205 683.5 0.8 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EER27109.1 - 6.2e-72 242.5 2.1 6.2e-72 242.5 2.1 2.9 3 0 0 3 3 2 1 AAA domain AAA_12 PF13087.6 EER27109.1 - 2.8e-61 206.6 0.0 5.6e-61 205.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EER27109.1 - 1.9e-09 37.5 0.2 1.8e-05 24.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EER27109.1 - 5.5e-09 36.1 0.0 0.0066 16.2 0.1 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EER27109.1 - 2.5e-08 34.4 0.0 1.5e-07 31.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 EER27109.1 - 3.5e-07 30.1 4.7 3.8e-07 30.0 0.3 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain zf-CCHC PF00098.23 EER27109.1 - 0.00037 20.4 2.3 0.00037 20.4 2.3 3.7 3 0 0 3 3 3 1 Zinc knuckle ResIII PF04851.15 EER27109.1 - 0.013 15.5 0.0 0.088 12.8 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EER27109.1 - 0.015 15.6 0.6 1.5 9.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 EER27109.1 - 0.015 15.0 0.2 0.056 13.2 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Med9 PF07544.13 EER27109.1 - 0.072 13.2 1.8 0.24 11.5 1.8 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF2075 PF09848.9 EER27109.1 - 0.14 11.4 1.2 5.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) HAUS6_N PF14661.6 EER27109.1 - 0.37 10.3 10.7 0.15 11.7 4.5 2.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus zf-CCHC_4 PF14392.6 EER27109.1 - 3.1 7.6 15.5 0.12 12.2 1.3 3.5 2 1 1 3 3 3 0 Zinc knuckle PhoLip_ATPase_C PF16212.5 EER27110.1 - 3.6e-79 266.1 20.5 3.6e-79 266.1 20.5 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EER27110.1 - 5.9e-21 73.9 1.1 5.9e-21 73.9 1.1 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EER27110.1 - 1.2e-12 47.7 0.0 5.4e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EER27110.1 - 4e-10 40.4 0.1 6.2e-07 29.9 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EER27110.1 - 4.7e-05 23.0 0.0 0.00016 21.3 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EER27110.1 - 0.028 14.2 0.5 0.056 13.2 0.5 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.18 EER27112.1 - 2e-55 187.3 17.7 4e-55 186.3 17.7 1.4 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4288 PF14119.6 EER27112.1 - 0.084 13.3 5.4 11 6.5 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Mg_trans_NIPA PF05653.14 EER27113.1 - 4.1e-13 49.1 4.5 4.2e-09 35.9 1.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EER27113.1 - 0.0021 18.2 1.8 0.0021 18.2 1.8 3.1 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EER27113.1 - 0.017 14.4 0.0 0.017 14.4 0.0 2.0 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport TMEM61 PF15105.6 EER27113.1 - 0.14 11.9 0.1 0.44 10.4 0.1 1.8 1 0 0 1 1 1 0 TMEM61 protein family TMEM252 PF15664.5 EER27113.1 - 2.1 8.1 5.6 33 4.2 0.0 3.0 2 1 0 2 2 2 0 Transmembrane protein 252 family SRF-TF PF00319.18 EER27114.1 - 3.7e-21 74.4 0.1 5.2e-21 73.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Abhydrolase_2 PF02230.16 EER27115.1 - 1.7e-25 90.1 0.1 1.2e-17 64.4 0.1 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EER27115.1 - 0.00022 20.7 0.0 0.00048 19.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EER27115.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER27115.1 - 0.003 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EER27115.1 - 0.073 12.7 0.0 0.23 11.1 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) BAAT_C PF08840.11 EER27115.1 - 0.094 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Sulfatase PF00884.23 EER27118.1 - 3e-62 210.8 0.6 3.8e-62 210.4 0.6 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EER27118.1 - 0.0086 15.7 1.7 0.095 12.3 1.7 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Tetraspanin PF00335.20 EER27119.1 - 0.00016 21.5 0.5 0.00028 20.7 0.5 1.4 1 0 0 1 1 1 1 Tetraspanin family DUF3325 PF11804.8 EER27119.1 - 2.4 8.4 5.1 5.1 7.3 0.0 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3325) Acetyltransf_1 PF00583.25 EER27120.1 - 0.0002 21.6 0.1 0.022 15.0 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER27120.1 - 0.0041 17.5 0.0 0.01 16.3 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER27120.1 - 0.22 11.5 0.0 18 5.3 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.11 EER27121.1 - 7.4e-08 31.8 1.5 9.7e-07 28.2 0.1 2.7 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) DUF1640 PF07798.11 EER27121.1 - 0.031 14.3 0.0 0.044 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) zf-ribbon_3 PF13248.6 EER27121.1 - 3.8 7.0 6.2 8.3 6.0 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain NAD_binding_6 PF08030.12 EER27122.1 - 8.8e-20 71.4 0.0 1.6e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EER27122.1 - 2.2e-18 66.6 8.4 2.2e-18 66.6 8.4 2.6 4 0 0 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EER27122.1 - 2.5e-12 46.8 0.0 8e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EER27122.1 - 0.014 16.0 0.0 11 6.7 0.0 2.6 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.6 EER27122.1 - 0.036 14.6 2.0 0.036 14.6 2.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) RNase_PH PF01138.21 EER27123.1 - 2.1e-20 73.5 0.1 7.3e-20 71.8 0.1 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_A22B PF04258.13 EER27124.1 - 8.7e-59 199.4 0.3 6.6e-58 196.5 0.3 2.0 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EER27124.1 - 0.00013 21.6 9.1 0.00033 20.2 4.7 2.5 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease FAST_1 PF06743.15 EER27124.1 - 0.055 13.4 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Pro_isomerase PF00160.21 EER27125.1 - 9.9e-56 188.4 0.0 1.1e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.18 EER27126.1 - 1.3e-07 30.5 0.0 1.6e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF1690 PF07956.11 EER27127.1 - 5.8e-40 136.9 13.4 1.4e-39 135.7 13.4 1.6 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) FliT PF05400.13 EER27127.1 - 0.016 16.0 3.1 0.016 16.0 3.1 2.2 2 1 0 2 2 2 0 Flagellar protein FliT Mononeg_mRNAcap PF14318.6 EER27127.1 - 0.028 13.7 0.1 0.031 13.5 0.1 1.2 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V Med9 PF07544.13 EER27127.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 PolyA_pol PF01743.20 EER27127.1 - 0.27 11.7 3.2 0.55 10.7 1.8 2.0 1 1 1 2 2 2 0 Poly A polymerase head domain Rotamase_2 PF13145.6 EER27127.1 - 9.5 7.1 8.5 15 6.4 0.7 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain POP1 PF06978.11 EER27128.1 - 3.9e-74 249.1 13.6 3.9e-74 249.1 13.6 1.9 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EER27128.1 - 2.7e-32 111.0 0.8 8.2e-32 109.4 0.8 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain Redoxin PF08534.10 EER27129.1 - 2.8e-38 130.9 0.0 3.1e-38 130.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EER27129.1 - 4.1e-10 39.6 0.0 5.1e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Hexokinase_2 PF03727.16 EER27130.1 - 2.2e-74 249.9 0.0 3.1e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EER27130.1 - 2.2e-72 243.2 0.0 3e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Yip1 PF04893.17 EER27131.1 - 0.062 13.0 5.6 0.11 12.2 5.6 1.3 1 0 0 1 1 1 0 Yip1 domain zf-C2HC5 PF06221.13 EER27132.1 - 1.1e-22 79.8 6.7 1.7e-22 79.1 6.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FAD_syn PF06574.12 EER27132.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase DUF604 PF04646.12 EER27133.1 - 2.4e-06 27.1 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EER27133.1 - 0.00013 21.4 0.0 0.00045 19.7 0.0 1.8 2 0 0 2 2 2 1 Fringe-like APH PF01636.23 EER27134.1 - 9.3e-11 42.1 0.0 9.9e-10 38.7 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER27134.1 - 1.9e-06 27.6 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DAO PF01266.24 EER27135.1 - 1.4e-23 84.0 0.0 1.7e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER27135.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fasciclin PF02469.22 EER27136.1 - 8.9e-42 142.3 0.1 6.2e-25 87.9 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Suc_Fer-like PF06999.12 EER27136.1 - 0.081 12.8 0.2 0.81 9.5 0.0 2.1 2 0 0 2 2 2 0 Sucrase/ferredoxin-like Pkinase PF00069.25 EER27137.1 - 3.4e-65 220.0 0.0 1.3e-64 218.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Fungal_KA1 PF16797.5 EER27137.1 - 6.8e-36 122.5 1.2 1.3e-35 121.6 1.2 1.5 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase_Tyr PF07714.17 EER27137.1 - 2.2e-32 112.4 0.0 2.6e-31 108.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EER27137.1 - 0.002 17.2 0.0 0.0047 15.9 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EER27137.1 - 0.0026 17.1 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Alpha-amylase PF00128.24 EER27137.1 - 0.0029 17.2 0.0 0.0056 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Kdo PF06293.14 EER27137.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER27137.1 - 0.014 15.3 0.2 0.14 12.0 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER27137.1 - 0.06 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase 14-3-3 PF00244.20 EER27137.1 - 0.14 11.6 0.5 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 14-3-3 protein Zn_clus PF00172.18 EER27138.1 - 1e-08 35.1 7.4 1.5e-08 34.6 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.10 EER27140.1 - 3e-44 151.5 1.4 2.9e-42 145.0 1.4 2.7 1 1 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF772 PF05598.11 EER27140.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Transposase domain (DUF772) TYW3 PF02676.14 EER27141.1 - 1.2e-75 253.6 0.0 1.5e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 PAM2 PF07145.15 EER27142.1 - 0.0015 18.1 0.2 0.0065 16.1 0.2 2.2 1 0 0 1 1 1 1 Ataxin-2 C-terminal region ARPC4 PF05856.12 EER27143.1 - 3.2e-79 264.4 3.4 3.5e-79 264.2 3.4 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 EER27144.1 - 3.9e-51 174.0 0.0 5e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER27144.1 - 3.6e-14 53.1 2.6 8.4e-14 51.9 2.6 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EER27144.1 - 4.6e-10 39.1 0.0 1.4e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family KAP_NTPase PF07693.14 EER27144.1 - 0.052 12.8 0.2 0.075 12.3 0.2 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF4554 PF15091.6 EER27144.1 - 0.14 11.1 2.2 0.22 10.4 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) T3SSipB PF16535.5 EER27144.1 - 0.55 10.7 8.5 0.39 11.2 3.5 2.7 2 0 0 2 2 2 0 Type III cell invasion protein SipB 4HBT PF03061.22 EER27145.1 - 3.1e-10 40.3 0.0 4.7e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EER27145.1 - 0.026 14.7 0.0 0.04 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) TRI12 PF06609.13 EER27146.1 - 2.4e-13 49.4 6.9 2.8e-13 49.2 6.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EER27146.1 - 4.9e-05 22.4 15.9 8.7e-05 21.6 11.7 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER27146.1 - 1.1 8.0 14.7 0.21 10.4 10.5 1.7 2 0 0 2 2 2 0 Sugar (and other) transporter Zn_ribbon_17 PF17120.5 EER27147.1 - 5.1e-09 35.6 16.6 1.5e-08 34.2 16.6 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EER27147.1 - 2e-07 31.5 15.8 0.0037 18.1 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat RWD PF05773.22 EER27147.1 - 0.00087 19.6 0.0 0.0024 18.2 0.0 1.7 1 0 0 1 1 1 1 RWD domain Stc1 PF12898.7 EER27147.1 - 0.0073 16.8 7.0 0.018 15.6 6.7 1.9 1 1 0 1 1 1 1 Stc1 domain zf-RING_10 PF16685.5 EER27147.1 - 0.15 12.2 6.7 0.32 11.1 6.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_2 PF13639.6 EER27147.1 - 0.3 11.5 13.6 0.75 10.2 13.6 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_UBOX PF13445.6 EER27147.1 - 1.9 8.6 10.7 4.9 7.3 10.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger UQ_con PF00179.26 EER27148.1 - 4.8e-47 159.1 0.0 5.4e-47 159.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER27148.1 - 0.00032 20.4 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EER27148.1 - 0.015 15.1 0.1 0.031 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EER27148.1 - 0.087 13.1 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.20 EER27149.1 - 8.3e-29 99.6 0.1 8.3e-29 99.6 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L24e Ribosomal_S30 PF04758.14 EER27150.1 - 4.3e-30 103.7 8.8 4.7e-30 103.6 8.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Acetyltransf_1 PF00583.25 EER27151.1 - 5.5e-11 42.7 0.2 6.9e-11 42.4 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER27151.1 - 1.9e-08 34.3 0.0 2.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER27151.1 - 4.1e-07 30.3 0.2 5.9e-07 29.8 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EER27151.1 - 0.16 12.7 0.0 0.2 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lyase_1 PF00206.20 EER27152.1 - 5.9e-112 374.1 0.0 7.8e-112 373.7 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EER27152.1 - 4.4e-21 75.0 0.0 1.3e-20 73.6 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.12 EER27152.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Abhydrolase_3 PF07859.13 EER27153.1 - 3e-61 206.9 0.1 4e-61 206.6 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EER27153.1 - 3.8e-07 29.8 0.0 1.6e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EER27153.1 - 4e-05 22.7 0.3 0.00012 21.1 0.3 1.6 1 1 0 1 1 1 1 Carboxylesterase family Esterase_phd PF10503.9 EER27153.1 - 0.0039 16.7 0.0 0.0088 15.6 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase FMO-like PF00743.19 EER27154.1 - 6.8e-98 328.4 0.0 8.2e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EER27154.1 - 3.6e-11 42.9 0.0 2.7e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER27154.1 - 1.1e-10 41.3 0.0 4.2e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER27154.1 - 2.1e-08 33.7 0.0 5.2e-07 29.1 0.0 2.6 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EER27154.1 - 8.3e-07 29.1 0.0 2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER27154.1 - 2.9e-05 23.8 0.0 0.065 12.8 0.1 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EER27154.1 - 0.00042 20.3 0.1 0.082 12.9 0.0 3.5 3 2 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EER27154.1 - 0.0057 17.2 0.0 4.3 8.0 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EER27154.1 - 0.052 12.9 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase F420_oxidored PF03807.17 EER27154.1 - 0.061 13.9 0.2 21 5.8 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Amino_oxidase PF01593.24 EER27154.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Cyclin PF08613.11 EER27155.1 - 4.8e-06 27.0 0.5 2.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EER27155.1 - 0.0092 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Pyrid_oxidase_2 PF13883.6 EER27156.1 - 6.1e-33 114.2 0.0 8.7e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ipi1_N PF12333.8 EER27157.1 - 2.5e-26 92.2 1.0 5.5e-26 91.1 0.0 2.1 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.17 EER27158.1 - 0.00017 21.3 0.2 0.028 14.2 0.0 3.0 3 0 0 3 3 3 1 Roadblock/LC7 domain YtxH PF12732.7 EER27159.1 - 0.0082 16.7 1.6 0.0097 16.4 1.6 1.1 1 0 0 1 1 1 1 YtxH-like protein DUF4230 PF14014.6 EER27159.1 - 0.025 14.8 0.1 0.028 14.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DUF883 PF05957.13 EER27159.1 - 0.083 13.5 0.7 0.099 13.3 0.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) LAS2 PF15792.5 EER27159.1 - 0.087 13.4 0.6 0.13 12.8 0.6 1.3 1 1 0 1 1 1 0 Lung adenoma susceptibility protein 2 ATP-synt_B PF00430.18 EER27159.1 - 0.12 12.5 1.2 0.13 12.3 1.2 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Tubulin PF00091.25 EER27160.1 - 1.4e-48 165.8 0.0 8.2e-25 88.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EER27160.1 - 1.4e-43 148.1 0.5 3.2e-43 146.9 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Abhydrolase_3 PF07859.13 EER27161.1 - 2.7e-24 86.2 0.0 3.7e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EER27161.1 - 4.1e-22 78.6 0.0 5.5e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EER27161.1 - 0.0033 16.9 0.0 0.011 15.2 0.0 1.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family COesterase PF00135.28 EER27161.1 - 0.035 13.0 0.3 5.1 5.8 0.1 2.1 2 0 0 2 2 2 0 Carboxylesterase family DUF2974 PF11187.8 EER27161.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.16 EER27161.1 - 0.079 12.8 0.0 0.22 11.3 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PMI_typeI PF01238.21 EER27162.1 - 9.8e-145 482.4 0.0 1.1e-144 482.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EER27162.1 - 0.015 15.0 0.0 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.19 EER27162.1 - 0.016 15.1 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF1325 PF07039.11 EER27163.1 - 2.3e-34 118.3 0.0 4.8e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 EER27163.1 - 0.11 12.3 0.1 0.23 11.3 0.1 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain NICE-1 PF15845.5 EER27163.1 - 0.34 11.7 6.8 0.089 13.6 2.4 2.1 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family AMP-binding PF00501.28 EER27164.1 - 1.2e-39 136.1 0.0 1.6e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER27164.1 - 5.4e-08 33.7 0.1 1.5e-06 29.1 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GTP_cyclohydro2 PF00925.20 EER27165.1 - 2.8e-58 196.1 0.0 4.3e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II PT PF04886.12 EER27165.1 - 0.017 14.7 2.9 0.047 13.2 2.9 1.8 1 0 0 1 1 1 0 PT repeat Methyltransf_23 PF13489.6 EER27166.1 - 8e-16 58.3 0.0 1e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER27166.1 - 1.6e-14 54.3 0.0 6.1e-14 52.5 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER27166.1 - 4.4e-14 52.5 0.0 8.4e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER27166.1 - 1.1e-13 51.6 0.0 3.1e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER27166.1 - 4.8e-13 49.7 0.0 1.7e-12 47.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER27166.1 - 3.4e-07 29.8 0.0 6e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EER27166.1 - 2e-05 24.6 0.0 4.1e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EER27166.1 - 0.0053 15.9 0.0 0.013 14.6 0.0 1.6 2 0 0 2 2 2 1 DREV methyltransferase Methyltransf_9 PF08003.11 EER27166.1 - 0.025 13.5 0.0 0.046 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) tRNA_U5-meth_tr PF05958.11 EER27166.1 - 0.12 11.4 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NNMT_PNMT_TEMT PF01234.17 EER27166.1 - 0.13 11.4 0.2 1.5 8.0 0.0 2.2 2 1 0 2 2 2 0 NNMT/PNMT/TEMT family DUF3425 PF11905.8 EER27167.1 - 2.2e-26 92.3 1.5 5e-26 91.1 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 EER27167.1 - 0.0014 18.6 10.1 0.0051 16.9 10.1 1.9 1 1 0 1 1 1 1 bZIP transcription factor NPV_P10 PF05531.12 EER27167.1 - 0.2 12.1 0.9 0.45 11.0 0.5 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein NBD_C PF17042.5 EER27167.1 - 0.4 11.2 3.6 0.72 10.3 3.6 1.3 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain PIEZO PF15917.5 EER27167.1 - 0.44 10.0 3.6 0.67 9.4 3.6 1.2 1 0 0 1 1 1 0 Piezo bZIP_2 PF07716.15 EER27167.1 - 6.9 6.8 12.3 4.1 7.6 9.5 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Actin PF00022.19 EER27168.1 - 7.6e-115 383.8 0.0 4.8e-114 381.1 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EER27168.1 - 0.029 13.2 0.0 0.18 10.6 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein EamA PF00892.20 EER27169.1 - 8.5e-09 35.7 28.0 5e-05 23.5 15.0 2.5 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 EER27169.1 - 0.0085 15.1 14.6 0.016 14.2 11.6 2.5 2 1 0 2 2 2 1 Ceramide synthase regulator Saf_2TM PF18303.1 EER27169.1 - 1.3 8.6 4.0 1.1 8.9 0.1 2.5 2 1 1 3 3 3 0 SAVED-fused 2TM effector domain Aldo_ket_red PF00248.21 EER27170.1 - 8.1e-52 176.2 0.0 9.2e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SLAC1 PF03595.17 EER27171.1 - 1.1e-82 277.9 56.3 1.3e-82 277.7 56.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel AA_permease PF00324.21 EER27172.1 - 5.6e-131 437.4 38.8 6.9e-131 437.1 38.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER27172.1 - 1e-36 126.7 40.1 1.4e-36 126.3 40.1 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM213 PF15192.6 EER27172.1 - 0.088 12.8 0.2 0.31 11.0 0.2 1.9 1 0 0 1 1 1 0 TMEM213 family DUF4231 PF14015.6 EER27172.1 - 5.6 7.5 0.0 5.6 7.5 0.0 5.3 5 1 1 6 6 6 0 Protein of unknown function (DUF4231) Wtap PF17098.5 EER27173.1 - 0.00085 19.3 0.5 0.0024 17.8 0.5 1.8 1 0 0 1 1 1 1 WTAP/Mum2p family SlyX PF04102.12 EER27173.1 - 0.004 17.7 8.4 0.12 13.0 0.3 3.8 4 1 0 4 4 4 2 SlyX DUF2200 PF09966.9 EER27173.1 - 0.042 14.0 0.1 0.12 12.5 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) HTH_31 PF13560.6 EER27173.1 - 0.14 12.5 3.6 3.6 8.0 1.9 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain FTA4 PF13093.6 EER27174.1 - 5e-58 196.3 1.4 5.8e-58 196.1 1.4 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Takusan PF04822.13 EER27174.1 - 0.092 12.6 1.8 0.2 11.6 1.8 1.6 1 0 0 1 1 1 0 Takusan HAD_2 PF13419.6 EER27175.1 - 8.5e-07 29.2 0.0 2e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER27175.1 - 0.0025 17.8 0.1 0.0041 17.1 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like EF-hand_14 PF17959.1 EER27175.1 - 0.14 12.5 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain Ribosomal_L5e PF17144.4 EER27176.1 - 3.3e-79 264.6 0.5 8.8e-79 263.2 0.3 1.8 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EER27176.1 - 1.7e-33 115.4 7.3 1.7e-33 115.4 7.3 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region DUF3135 PF11333.8 EER27177.1 - 0.0028 17.9 0.2 0.22 11.8 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3135) LRR_6 PF13516.6 EER27177.1 - 0.12 12.4 10.1 53 4.2 0.1 6.5 7 0 0 7 7 7 0 Leucine Rich repeat F-box PF00646.33 EER27178.1 - 7.1e-06 25.8 1.3 8.9e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EER27178.1 - 1.6e-05 24.7 0.1 3.7e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like Phe_ZIP PF08916.11 EER27178.1 - 0.07 13.8 0.2 0.44 11.3 0.1 2.4 2 0 0 2 2 2 0 Phenylalanine zipper ABC_membrane_2 PF06472.15 EER27179.1 - 5.7e-103 344.0 1.2 8e-103 343.5 1.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EER27179.1 - 1e-20 74.6 0.0 2e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EER27179.1 - 8.9e-05 22.4 0.0 0.00026 20.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EER27179.1 - 0.003 18.1 0.1 0.014 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EER27179.1 - 0.021 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Reticulon PF02453.17 EER27179.1 - 0.026 14.5 0.0 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 Reticulon SMC_N PF02463.19 EER27179.1 - 0.031 13.7 0.1 0.11 11.9 0.0 1.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EER27179.1 - 0.096 13.1 0.5 0.45 10.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EER27179.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Phosphorylase PF00343.20 EER27180.1 - 0 1050.5 0.0 0 1050.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.20 EER27181.1 - 7e-115 384.0 0.3 8.1e-115 383.8 0.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EER27181.1 - 3.1e-15 56.1 1.3 2.6e-10 40.0 0.3 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EER27181.1 - 4.3e-05 23.0 0.4 0.058 12.7 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EER27181.1 - 0.0027 17.9 0.2 0.71 10.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EER27181.1 - 0.042 12.9 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain WAK PF08488.11 EER27181.1 - 0.045 14.3 0.1 0.4 11.2 0.0 2.2 2 0 0 2 2 2 0 Wall-associated kinase AAA_29 PF13555.6 EER27181.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 EER27182.1 - 3.6e-67 226.5 0.0 4.5e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27182.1 - 3.2e-32 111.9 0.0 4.2e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EER27182.1 - 1.4e-05 24.3 0.1 1.8e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EER27182.1 - 0.0001 21.8 0.1 0.00031 20.1 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EER27182.1 - 0.00044 19.7 0.0 0.022 14.1 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EER27182.1 - 0.00079 19.4 0.0 0.0025 17.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EER27182.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EER27182.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 EER27183.1 - 1.6e-144 481.3 0.0 2.3e-144 480.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EER27183.1 - 1.1e-07 31.8 6.2 1.1e-05 25.2 0.3 3.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 EER27183.1 - 2.1e-07 30.9 0.0 0.0015 18.5 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.12 EER27183.1 - 0.0027 18.2 0.7 0.041 14.4 0.0 2.8 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking PIEZO PF15917.5 EER27183.1 - 0.14 11.6 0.8 0.34 10.4 0.8 1.5 1 0 0 1 1 1 0 Piezo Cullin PF00888.22 EER27184.1 - 1.2e-191 638.5 7.9 1.7e-191 638.0 7.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EER27184.1 - 1.3e-26 92.4 4.7 2e-26 91.8 2.9 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain PRD PF00874.20 EER27184.1 - 0.67 10.3 4.6 4 7.8 0.3 4.1 5 0 0 5 5 5 0 PRD domain Cupin_1 PF00190.22 EER27185.1 - 1.8e-06 27.6 0.1 2.5e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 EER27185.1 - 1.6e-05 24.6 0.1 2.6e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 EER27185.1 - 0.0032 17.7 0.0 0.0042 17.3 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 EER27185.1 - 0.14 11.8 0.0 0.8 9.4 0.0 1.9 1 1 1 2 2 2 0 Cupin MARVEL PF01284.23 EER27186.1 - 0.0017 18.4 0.5 0.003 17.6 0.5 1.4 1 0 0 1 1 1 1 Membrane-associating domain Mit_KHE1 PF10173.9 EER27187.1 - 9.7e-65 218.2 0.3 1.3e-64 217.8 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related End3 PF12761.7 EER27188.1 - 4.9e-71 239.0 0.6 7e-71 238.5 0.6 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EER27188.1 - 6.9e-51 170.6 0.2 1.3e-48 163.2 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EER27188.1 - 7.1e-08 31.5 0.3 1.8e-07 30.2 0.3 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EER27188.1 - 1.2e-06 28.8 0.4 4.7e-06 27.0 0.0 2.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EER27188.1 - 0.0001 21.9 0.2 0.00037 20.2 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EER27188.1 - 0.002 18.0 0.1 0.0047 16.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EER27188.1 - 0.0026 17.2 1.0 0.0094 15.4 0.2 2.2 2 0 0 2 2 2 1 EF hand DUF16 PF01519.16 EER27188.1 - 0.21 12.1 1.4 0.5 10.9 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.6 EER27188.1 - 0.39 10.0 4.3 0.57 9.5 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SNF2_N PF00176.23 EER27189.1 - 7.7e-64 215.6 0.2 1.8e-63 214.4 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER27189.1 - 2.7e-21 76.0 0.1 1.3e-20 73.8 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER27189.1 - 2.5e-08 34.1 0.1 7.9e-08 32.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EER27189.1 - 0.0015 17.8 0.0 0.084 12.0 0.0 3.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EER27189.1 - 0.0019 17.5 0.0 0.0044 16.3 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DSPc PF00782.20 EER27191.1 - 8.3e-13 48.3 0.1 1.7e-12 47.3 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EER27191.1 - 0.054 13.8 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain UK PF02512.14 EER27191.1 - 0.063 13.8 0.1 0.11 13.0 0.1 1.3 1 0 0 1 1 1 0 Virulence determinant zf-C2H2 PF00096.26 EER27192.1 - 4.2e-08 33.2 9.5 0.0018 18.6 0.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EER27192.1 - 0.00032 20.9 0.0 0.00052 20.2 0.0 1.5 1 0 0 1 1 1 1 Aberrant zinc-finger FAM76 PF16046.5 EER27192.1 - 0.00055 19.4 0.5 0.00055 19.4 0.5 1.6 2 0 0 2 2 2 1 FAM76 protein DUF4164 PF13747.6 EER27192.1 - 0.0033 17.7 2.6 0.0075 16.5 2.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) MPS2 PF17060.5 EER27192.1 - 0.0096 15.2 1.5 0.012 14.9 1.5 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 HAUS-augmin3 PF14932.6 EER27192.1 - 0.01 15.4 0.8 0.016 14.8 0.8 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Trimer_CC PF08954.11 EER27192.1 - 0.017 14.7 3.6 0.017 14.7 3.6 1.8 2 0 0 2 2 2 0 Trimerisation motif zf-C2H2_4 PF13894.6 EER27192.1 - 0.025 15.4 6.8 15 6.7 0.2 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger Spc29 PF17082.5 EER27192.1 - 0.038 13.8 1.4 0.057 13.3 1.4 1.2 1 0 0 1 1 1 0 Spindle Pole Component 29 zf-H2C2_2 PF13465.6 EER27192.1 - 0.081 13.4 13.9 4.8 7.8 0.8 3.9 3 1 0 3 3 3 0 Zinc-finger double domain DivIC PF04977.15 EER27192.1 - 0.082 12.7 1.7 0.16 11.7 1.7 1.4 1 0 0 1 1 1 0 Septum formation initiator Ax_dynein_light PF10211.9 EER27192.1 - 0.19 11.7 2.4 0.28 11.1 2.4 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DUF4407 PF14362.6 EER27192.1 - 0.23 10.8 0.4 0.34 10.2 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1192 PF06698.11 EER27192.1 - 0.26 11.4 2.0 0.72 9.9 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) ATG16 PF08614.11 EER27192.1 - 0.44 10.8 5.7 0.72 10.0 5.7 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) RVT_1 PF00078.27 EER27194.1 - 5.2e-05 22.9 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Urb2 PF10441.9 EER27195.1 - 1.6e-65 220.9 0.1 6.7e-65 218.9 0.0 2.2 2 0 0 2 2 2 1 Urb2/Npa2 family Metallothio_2 PF01439.18 EER27196.1 - 0.096 13.6 16.7 0.11 13.4 1.9 2.8 2 0 0 2 2 2 0 Metallothionein Myb_DNA-binding PF00249.31 EER27197.1 - 0.00029 21.0 0.0 0.0038 17.4 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER27197.1 - 0.0039 17.4 0.1 0.0072 16.6 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pkinase PF00069.25 EER27198.1 - 6.7e-27 94.5 0.0 3.8e-26 92.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27198.1 - 1.2e-12 47.6 0.0 5.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase XRCC4 PF06632.12 EER27200.1 - 0.036 12.9 2.3 0.049 12.5 2.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Spore_YhcN_YlaJ PF09580.10 EER27200.1 - 0.052 13.6 2.5 0.084 13.0 2.5 1.4 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Suf PF05843.14 EER27200.1 - 0.097 12.6 4.7 0.12 12.4 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Med3 PF11593.8 EER27200.1 - 0.18 11.0 7.8 0.22 10.7 7.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Hydin_ADK PF17213.3 EER27200.1 - 0.62 10.3 4.0 0.84 9.9 3.7 1.4 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF5321 PF17254.2 EER27200.1 - 1.1 8.6 5.1 16 4.9 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5321) FAM70 PF14967.6 EER27200.1 - 2.3 7.6 5.4 2.9 7.3 5.4 1.2 1 0 0 1 1 1 0 FAM70 protein GST_C_6 PF17171.4 EER27201.1 - 2.3e-18 65.7 0.9 5e-18 64.6 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EER27201.1 - 3.3e-06 27.4 0.3 5.3e-06 26.8 0.3 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EER27201.1 - 0.00012 22.7 0.4 0.00052 20.7 0.1 2.1 2 1 1 3 3 3 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 EER27201.1 - 0.02 14.9 0.0 0.046 13.8 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 EER27202.1 - 2.7e-12 47.2 0.0 5.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER27202.1 - 2.9e-11 43.9 0.0 1.2e-10 41.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER27202.1 - 7.9e-10 38.8 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER27202.1 - 1.6e-09 38.4 0.0 3.8e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER27202.1 - 2.5e-09 37.1 0.0 3.6e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER27202.1 - 1.4e-05 24.5 0.0 3e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EER27202.1 - 0.00034 20.0 0.0 0.00048 19.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EER27202.1 - 0.00081 19.0 0.0 0.0028 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EER27202.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.6 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_20 PF12147.8 EER27202.1 - 0.0017 17.6 0.0 0.0024 17.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 EER27202.1 - 0.0041 17.1 0.0 0.0066 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EER27202.1 - 0.0042 16.6 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_7 PF03492.15 EER27202.1 - 0.012 14.8 0.2 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase PCMT PF01135.19 EER27202.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_5 PF01795.19 EER27202.1 - 0.019 14.5 0.0 3.4 7.1 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family CheR PF01739.18 EER27202.1 - 0.023 14.2 0.0 1.4 8.4 0.0 2.5 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain ADH_zinc_N PF00107.26 EER27202.1 - 0.042 13.8 0.0 0.083 12.9 0.0 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Bin3 PF06859.12 EER27202.1 - 0.13 12.9 0.0 0.3 11.7 0.0 1.7 1 1 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_8 PF05148.15 EER27202.1 - 0.14 12.0 0.0 8.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase CDC14 PF08045.11 EER27203.1 - 4.7e-113 377.0 0.0 4e-112 374.0 0.0 1.9 1 1 0 1 1 1 1 Cell division control protein 14, SIN component Sugar_tr PF00083.24 EER27204.1 - 8.2e-91 305.1 16.8 1e-90 304.8 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER27204.1 - 1.8e-13 50.2 43.4 6.3e-09 35.2 12.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily UAA PF08449.11 EER27204.1 - 0.02 14.1 0.2 0.038 13.2 0.2 1.3 1 0 0 1 1 1 0 UAA transporter family polyprenyl_synt PF00348.17 EER27205.1 - 2.3e-61 207.1 0.0 3.4e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Translin PF01997.16 EER27205.1 - 0.15 12.0 0.3 5.5 6.9 0.0 2.2 1 1 1 2 2 2 0 Translin family DUF1771 PF08590.10 EER27206.1 - 9.7e-25 86.7 7.8 9.7e-25 86.7 7.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EER27206.1 - 1.3e-11 44.7 0.8 4.8e-11 42.9 0.2 2.3 2 0 0 2 2 2 1 Smr domain DUF4407 PF14362.6 EER27206.1 - 0.55 9.5 2.4 0.86 8.9 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.21 EER27208.1 - 2.9e-41 141.6 0.0 6.5e-39 133.9 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family ALMT PF11744.8 EER27208.1 - 0.21 10.4 0.1 0.28 10.0 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Rit1_C PF17184.4 EER27209.1 - 7.3e-97 324.1 0.0 9.2e-97 323.7 0.0 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EER27209.1 - 6.6e-18 65.0 0.0 1.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain HAD_2 PF13419.6 EER27210.1 - 1.4e-21 77.4 0.0 1.8e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EER27210.1 - 2.2e-08 34.7 0.3 3.1e-07 30.9 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 EER27210.1 - 4.6e-06 26.5 0.0 6.3e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_like PF13242.6 EER27210.1 - 0.00011 22.1 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EER27210.1 - 0.026 14.9 0.0 0.035 14.5 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Jagunal PF07086.12 EER27212.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis NUDIX PF00293.28 EER27213.1 - 1.5e-17 63.8 0.0 2.2e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 EER27214.1 - 1e-07 32.1 0.0 2.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain zf-C3HC4_3 PF13920.6 EER27215.1 - 6.5e-12 45.1 6.8 1.3e-11 44.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EER27215.1 - 2.4e-05 24.1 7.3 0.00013 21.8 7.3 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EER27215.1 - 2.5e-05 24.0 8.9 5.3e-05 23.0 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER27215.1 - 0.0012 19.2 9.6 0.0031 17.8 9.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EER27215.1 - 0.0037 17.2 7.5 0.0074 16.2 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EER27215.1 - 2.3 8.1 11.6 25 4.8 11.6 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EER27215.1 - 5.2 6.9 6.6 13 5.7 6.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EST1_DNA_bind PF10373.9 EER27216.1 - 7.1e-10 38.8 5.5 4.5e-09 36.2 2.6 2.8 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain TFIIB PF00382.19 EER27217.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Cyclin_N PF00134.23 EER27217.1 - 0.12 12.2 0.0 2.9 7.6 0.0 2.5 3 0 0 3 3 3 0 Cyclin, N-terminal domain Autophagy_N PF03986.13 EER27218.1 - 3.8e-45 153.2 0.0 6.5e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EER27218.1 - 1.4e-15 56.5 0.5 2.4e-15 55.7 0.5 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EER27218.1 - 9.6e-14 51.7 0.2 2.4e-13 50.5 0.1 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Striatin PF08232.12 EER27219.1 - 0.036 14.7 0.6 0.036 14.7 0.6 1.6 2 0 0 2 2 2 0 Striatin family Dicty_CAR PF05462.11 EER27220.1 - 0.16 11.1 1.7 0.31 10.1 1.7 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Glycos_transf_2 PF00535.26 EER27221.1 - 8.1e-21 74.6 0.0 3.2e-19 69.4 0.0 2.8 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EER27221.1 - 5.7e-07 29.6 0.0 0.0039 17.1 0.0 3.1 2 1 1 3 3 3 2 Glycosyltransferase like family 2 Peptidase_S10 PF00450.22 EER27222.1 - 9.5e-32 110.9 0.2 4.2e-16 59.4 0.0 3.0 1 1 2 3 3 3 3 Serine carboxypeptidase FliD_N PF02465.18 EER27223.1 - 0.019 15.6 1.1 0.048 14.4 1.1 1.7 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Exonuc_VII_L PF02601.15 EER27223.1 - 0.03 13.9 3.8 0.06 12.9 3.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Matrilin_ccoil PF10393.9 EER27223.1 - 0.036 13.9 6.2 0.035 14.0 2.4 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Tweety PF04906.13 EER27223.1 - 0.71 8.5 3.8 1 8.0 3.8 1.1 1 0 0 1 1 1 0 Tweety Phage_GPO PF05929.11 EER27223.1 - 0.75 9.4 7.2 1.2 8.7 7.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase PRKG1_interact PF15898.5 EER27223.1 - 3.1 8.8 12.2 22 6.0 11.9 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Ytp1 PF10355.9 EER27224.1 - 3.3e-72 243.0 15.4 3.3e-72 243.0 15.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EER27224.1 - 8.1e-30 102.7 6.2 8.1e-30 102.7 6.2 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF2427) GHMP_kinases_N PF00288.26 EER27224.1 - 0.34 11.2 1.6 1 9.7 0.2 2.3 2 0 0 2 2 2 0 GHMP kinases N terminal domain AWPM-19 PF05512.11 EER27224.1 - 0.38 10.9 6.7 0.39 10.9 1.0 3.2 2 1 1 3 3 3 0 AWPM-19-like family DUF3675 PF12428.8 EER27224.1 - 0.47 11.0 3.5 16 6.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3675) Hydantoinase_A PF01968.18 EER27225.1 - 0.0035 16.6 0.0 0.0047 16.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydantoinase_B PF02538.14 EER27225.1 - 0.006 15.0 0.0 0.0072 14.8 0.0 1.3 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase ThiF PF00899.21 EER27226.1 - 2.2e-34 118.9 0.0 3e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family MFS_1 PF07690.16 EER27228.1 - 2.4e-38 132.0 27.1 1.7e-37 129.2 27.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF63 PF01889.17 EER27228.1 - 0.013 15.7 0.4 0.013 15.7 0.4 1.7 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 Na_H_Exchanger PF00999.21 EER27229.1 - 2.9e-60 204.1 43.9 4.2e-60 203.6 43.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peroxin-3 PF04882.12 EER27230.1 - 2.7e-164 547.6 3.3 3.2e-164 547.4 3.3 1.0 1 0 0 1 1 1 1 Peroxin-3 ATG101 PF07855.12 EER27231.1 - 1.4e-57 194.1 0.0 1.6e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 TB2_DP1_HVA22 PF03134.19 EER27232.1 - 2.8e-27 94.4 9.1 2.8e-27 94.4 9.1 1.7 1 1 1 2 2 2 2 TB2/DP1, HVA22 family PgaD PF13994.6 EER27232.1 - 0.34 11.0 4.0 0.15 12.2 0.9 1.8 2 1 0 2 2 2 0 PgaD-like protein RFX_DNA_binding PF02257.15 EER27233.1 - 1.9e-27 95.7 0.1 4.2e-27 94.6 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain PIG-X PF08320.12 EER27234.1 - 3.9e-70 236.0 0.1 6.1e-70 235.4 0.1 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ_C PF01556.18 EER27235.1 - 4.1e-38 130.8 1.9 5.5e-38 130.4 1.9 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EER27235.1 - 3e-28 97.7 2.3 4.8e-28 97.1 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DHHA1 PF02272.19 EER27235.1 - 0.23 11.9 0.8 0.46 10.9 0.8 1.6 1 0 0 1 1 1 0 DHHA1 domain MMR_HSR1_Xtn PF16897.5 EER27236.1 - 1.2e-34 118.5 1.9 5.3e-34 116.4 0.7 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EER27236.1 - 2.5e-22 78.7 0.2 5.8e-22 77.5 0.1 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.23 EER27236.1 - 3.1e-20 72.4 0.0 5.8e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EER27236.1 - 2.4e-12 46.7 0.0 3.8e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EER27236.1 - 0.00024 21.2 0.3 0.16 12.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 EER27236.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family MeaB PF03308.16 EER27236.1 - 0.097 11.6 0.1 0.18 10.8 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Torus PF16131.5 EER27237.1 - 3.2e-45 153.3 2.0 6.4e-45 152.3 0.1 2.3 3 0 0 3 3 3 1 Torus domain RRM_1 PF00076.22 EER27237.1 - 4.1e-08 32.9 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EER27237.1 - 0.00023 21.1 1.1 0.00041 20.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger domain Nup35_RRM_2 PF14605.6 EER27237.1 - 0.0041 17.1 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EER27237.1 - 0.069 13.1 1.5 0.12 12.3 1.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EER27237.1 - 1.9 8.4 3.9 3 7.8 3.9 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger HGTP_anticodon2 PF12745.7 EER27238.1 - 2.5e-79 266.5 4.2 2.5e-79 266.5 4.2 2.2 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EER27238.1 - 9.7e-73 244.8 0.0 6.1e-35 120.9 0.0 4.2 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EER27238.1 - 3e-40 138.1 0.0 8.4e-18 64.6 0.0 4.0 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.22 EER27238.1 - 3.9e-17 62.6 1.8 7.8e-17 61.6 0.1 2.4 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EER27238.1 - 2e-12 47.0 0.3 5.5e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase DUF5041 PF16444.5 EER27238.1 - 9.3e-05 22.8 0.4 0.0002 21.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5041) HGTP_anticodon PF03129.20 EER27238.1 - 0.0001 22.4 0.0 0.0001 22.4 0.0 2.2 2 1 0 2 2 2 1 Anticodon binding domain APH PF01636.23 EER27238.1 - 0.0025 17.8 2.8 0.0044 17.0 0.0 2.7 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EER27238.1 - 0.0028 17.0 0.0 0.99 8.7 0.0 2.7 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 EER27238.1 - 0.0041 16.8 0.0 0.11 12.1 0.0 2.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 DUF1682 PF07946.14 EER27238.1 - 0.05 12.8 11.6 0.11 11.7 11.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Cut12 PF11500.8 EER27239.1 - 4.6e-41 140.1 12.0 4.6e-41 140.1 12.0 4.1 4 1 0 4 4 4 1 Spindle pole body formation-associated protein FOXP-CC PF16159.5 EER27239.1 - 0.024 15.3 0.9 0.024 15.3 0.9 2.5 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF2730 PF10805.8 EER27239.1 - 1.4 9.0 10.3 3.1 7.9 1.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF89 PF01937.19 EER27240.1 - 7.6e-100 334.3 0.0 8.5e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 IF-2B PF01008.17 EER27240.1 - 0.038 13.2 0.1 0.057 12.6 0.1 1.3 1 1 0 1 1 1 0 Initiation factor 2 subunit family PPP5 PF08321.12 EER27241.1 - 1.1e-34 118.6 0.5 2.3e-34 117.6 0.5 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 EER27241.1 - 1.6e-32 113.7 0.1 2.5e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EER27241.1 - 1.4e-09 37.3 4.2 4.4e-05 23.1 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EER27241.1 - 6.4e-09 35.3 5.1 0.0077 16.3 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EER27241.1 - 1.1e-06 28.2 0.6 0.022 14.4 0.1 3.4 2 1 1 3 3 3 2 TPR repeat TPR_16 PF13432.6 EER27241.1 - 4.6e-05 24.0 2.2 0.48 11.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EER27241.1 - 5.3e-05 23.3 0.1 0.038 14.1 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EER27241.1 - 0.0008 19.6 2.1 0.61 10.6 0.1 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EER27241.1 - 0.0012 19.3 0.1 0.82 10.2 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EER27241.1 - 0.0048 17.4 0.2 2.5 8.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EER27241.1 - 0.0097 16.7 1.6 4.5 8.4 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EER27241.1 - 0.016 15.4 1.2 0.069 13.4 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 EER27242.1 - 1.7e-126 422.2 0.0 1.9e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EER27242.1 - 0.0054 15.9 0.0 0.0087 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Bestrophin PF01062.21 EER27243.1 - 8.1e-35 120.6 0.0 1.9e-34 119.4 0.0 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 EER27243.1 - 0.024 13.4 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE GSH_synth_ATP PF03917.17 EER27247.1 - 1.2e-139 465.3 0.0 1.3e-139 465.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EER27247.1 - 2e-27 95.6 0.0 3.4e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase RPN13_C PF16550.5 EER27247.1 - 0.17 12.1 0.1 0.45 10.7 0.1 1.7 1 0 0 1 1 1 0 UCH-binding domain SNF2_N PF00176.23 EER27248.1 - 1.4e-42 145.7 0.0 3.1e-42 144.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER27248.1 - 6.8e-19 68.3 0.0 1.8e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER27248.1 - 7.7e-08 32.5 0.1 2.3e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EER27248.1 - 0.00091 18.5 0.1 0.002 17.4 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EER27248.1 - 0.001 18.8 0.0 0.37 10.4 0.0 2.4 2 0 0 2 2 2 2 SWI2/SNF2 ATPase SAM_2 PF07647.17 EER27248.1 - 0.0067 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EOS1 PF12326.8 EER27248.1 - 2.9 7.8 4.3 2.1 8.3 0.1 2.8 2 1 0 2 2 2 0 N-glycosylation protein Abhydrolase_3 PF07859.13 EER27249.1 - 1.1e-42 146.3 0.0 1.3e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold SNF2_N PF00176.23 EER27250.1 - 1.3e-69 234.6 0.0 1.8e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EER27250.1 - 5.3e-17 61.5 0.0 1.3e-16 60.3 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EER27250.1 - 5e-13 49.4 0.0 7.2e-12 45.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EER27250.1 - 2.2e-10 40.2 7.8 5.3e-10 39.0 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER27250.1 - 3.4e-09 36.9 7.1 3.4e-09 36.9 7.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EER27250.1 - 8.9e-08 31.9 4.2 8.9e-08 31.9 4.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER27250.1 - 9.5e-08 31.8 7.4 2.3e-07 30.6 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EER27250.1 - 1.4e-07 31.7 3.9 3.5e-07 30.4 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EER27250.1 - 2.8e-07 30.5 7.1 4.1e-07 29.9 5.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 EER27250.1 - 9.5e-07 28.5 4.1 8.7e-06 25.5 4.9 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EER27250.1 - 3.3e-06 27.1 7.6 3.3e-06 27.1 7.6 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EER27250.1 - 5.9e-06 26.2 3.7 5.9e-06 26.2 3.7 1.8 2 0 0 2 2 1 1 zinc-RING finger domain DEAD PF00270.29 EER27250.1 - 0.0002 21.2 0.0 0.0006 19.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 EER27250.1 - 0.00081 19.2 4.9 0.0032 17.3 4.9 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EER27250.1 - 0.0012 18.5 1.9 0.0012 18.5 1.9 2.2 2 0 0 2 2 2 1 RING-like zinc finger U-box PF04564.15 EER27250.1 - 0.0014 18.7 0.0 0.004 17.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-ANAPC11 PF12861.7 EER27250.1 - 0.0029 17.6 1.3 0.0067 16.5 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 EER27250.1 - 0.057 13.3 2.9 4.2 7.3 0.5 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 EER27250.1 - 1.1 9.1 4.8 2.8 7.8 4.8 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RIX1 PF08167.12 EER27251.1 - 5.7e-60 202.3 4.3 1e-59 201.5 2.8 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis TPR_2 PF07719.17 EER27252.1 - 5.8e-08 32.3 4.5 0.062 13.4 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EER27252.1 - 3e-06 27.6 18.9 0.062 14.1 0.1 8.1 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EER27252.1 - 2.3e-05 24.8 8.2 0.029 14.9 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EER27252.1 - 7.7e-05 22.8 0.1 0.047 14.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EER27252.1 - 0.00034 19.9 4.1 0.069 12.3 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EER27252.1 - 0.0038 17.3 0.3 0.49 10.8 0.0 4.0 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER27252.1 - 0.0063 16.3 0.9 3.7 7.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EER27252.1 - 0.21 11.8 3.9 0.58 10.3 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER27252.1 - 0.21 11.9 5.9 10 6.5 0.1 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EER27252.1 - 0.91 10.2 12.0 19 6.0 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EER27252.1 - 2.4 9.0 7.2 19 6.2 0.1 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EER27252.1 - 4.2 7.6 5.9 33 4.8 0.1 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat NDUFA12 PF05071.16 EER27253.1 - 3.5e-31 107.9 3.3 4.3e-31 107.6 3.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 EER27254.1 - 3.8e-11 43.0 0.0 0.0002 21.3 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EER27254.1 - 2.3e-06 27.5 1.4 0.0033 17.5 0.3 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif LTV PF04180.14 EER27255.1 - 2.7e-121 405.9 9.2 3.1e-121 405.7 9.2 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 EER27256.1 - 2.2e-16 59.9 0.4 3.3e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EER27256.1 - 1.2e-06 28.2 0.1 4.6e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EER27256.1 - 7.7e-06 25.9 0.2 0.012 15.5 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EER27256.1 - 0.00015 21.9 1.4 0.2 11.7 0.3 3.0 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 EER27256.1 - 0.0052 16.1 0.1 0.0095 15.3 0.1 1.4 1 0 0 1 1 1 1 AIG1 family zf-C2H2_4 PF13894.6 EER27257.1 - 0.19 12.6 10.4 0.23 12.4 0.8 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EER27257.1 - 0.23 11.2 2.2 0.19 11.5 0.4 1.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 EER27257.1 - 4 8.1 11.9 4.9 7.8 0.8 4.2 3 1 1 4 4 4 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 EER27258.1 - 4e-12 45.9 7.3 1.9e-05 24.8 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 EER27258.1 - 1.2e-09 37.6 0.1 1.2e-09 37.6 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 EER27258.1 - 6.1e-09 36.0 7.6 0.00067 20.3 1.6 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EER27258.1 - 8.9e-08 32.2 2.8 8.9e-08 32.2 2.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EER27258.1 - 2.6e-05 24.4 0.5 0.18 12.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EER27258.1 - 0.0046 17.4 1.7 0.0046 17.4 1.7 2.3 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 EER27258.1 - 0.021 14.7 2.6 1.1 9.3 0.2 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 EER27258.1 - 0.11 12.9 1.6 3.1 8.3 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BolA PF01722.18 EER27258.1 - 0.11 12.7 0.7 0.59 10.4 0.2 2.5 2 1 0 2 2 2 0 BolA-like protein zf-BED PF02892.15 EER27258.1 - 0.65 10.1 3.7 3.5 7.7 0.8 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 EER27258.1 - 0.78 9.8 5.9 10 6.3 1.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 EER27260.1 - 1.1e-70 238.0 0.0 2.5e-70 236.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27260.1 - 7.5e-50 169.6 0.0 2.6e-49 167.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EER27260.1 - 8.8e-29 99.8 0.0 1.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EER27260.1 - 4.2e-15 55.9 0.1 8.7e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EER27260.1 - 3.6e-13 49.4 0.1 8.5e-13 48.2 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 EER27260.1 - 2.9e-08 33.4 0.0 0.00012 21.5 0.0 2.5 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 EER27260.1 - 1.7e-07 31.8 0.0 3.5e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 EER27260.1 - 0.00067 18.5 0.8 0.0011 17.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EER27260.1 - 0.032 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SAM_4 PF18017.1 EER27260.1 - 0.05 13.6 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Seadorna_VP7 PF07387.11 EER27260.1 - 0.16 11.0 0.1 0.49 9.4 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 MSA-2c PF12238.8 EER27260.1 - 0.23 11.4 2.8 0.63 10.0 0.0 2.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c Ribosomal_L5_C PF00673.21 EER27261.1 - 2.4e-30 104.6 0.0 3.9e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EER27261.1 - 6.7e-11 42.4 0.0 1.4e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 UCH PF00443.29 EER27262.1 - 1.5e-14 54.1 0.0 3.9e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER27262.1 - 1.8e-13 50.8 0.0 1.5e-05 24.7 0.0 2.5 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EnY2 PF10163.9 EER27262.1 - 0.077 13.4 0.3 3.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Transcription factor e(y)2 DUF5434 PF17502.2 EER27262.1 - 0.28 11.2 6.1 8.8 6.3 5.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5434) Pep3_Vps18 PF05131.14 EER27263.1 - 1.3e-45 154.9 0.0 3.7e-45 153.4 0.0 1.8 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EER27263.1 - 1.2e-08 35.0 6.4 4.8e-06 26.5 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EER27263.1 - 0.00026 20.6 0.4 0.00055 19.5 0.4 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EER27263.1 - 0.00063 19.4 4.3 0.002 17.9 4.3 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EER27263.1 - 0.00088 19.2 0.5 0.0022 17.9 0.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EER27263.1 - 0.00093 19.0 1.2 0.0027 17.5 1.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER27263.1 - 0.0056 17.0 0.9 0.014 15.7 0.9 1.7 1 0 0 1 1 1 1 Ring finger domain DUF2175 PF09943.9 EER27263.1 - 0.014 15.7 0.8 0.049 13.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) RPN1_RPN2_N PF17781.1 EER27263.1 - 0.016 14.6 0.1 0.09 12.2 0.0 2.2 3 0 0 3 3 3 0 RPN1/RPN2 N-terminal domain zf-RING_UBOX PF13445.6 EER27263.1 - 0.037 14.0 0.6 0.091 12.8 0.6 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EER27263.1 - 0.088 13.1 0.5 0.29 11.4 0.5 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain Vps39_2 PF10367.9 EER27263.1 - 0.15 12.5 0.0 0.48 10.9 0.0 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.25 EER27263.1 - 0.26 11.2 2.3 0.21 11.5 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CMD PF02627.20 EER27264.1 - 0.035 14.1 0.0 0.071 13.2 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Pkinase PF00069.25 EER27266.1 - 5.2e-54 183.4 0.0 7.2e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27266.1 - 9.2e-32 110.3 0.0 1.3e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER27266.1 - 5.9e-12 45.5 0.0 2.8e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EER27266.1 - 0.0067 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.13 EER27267.1 - 5.9e-32 110.5 0.0 1.1e-31 109.6 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Col_cuticle_N PF01484.17 EER27267.1 - 0.076 13.1 0.6 0.61 10.2 0.1 2.5 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.25 EER27268.1 - 2.3e-12 46.9 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27268.1 - 0.0027 17.0 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Acyl-CoA_dh_1 PF00441.24 EER27269.1 - 5e-29 101.5 1.9 8.7e-29 100.7 1.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EER27269.1 - 5.2e-20 71.4 0.0 1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EER27269.1 - 2.8e-16 60.2 0.3 1.2e-15 58.2 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EER27269.1 - 8.4e-12 45.5 3.5 1.6e-11 44.6 3.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EST1_DNA_bind PF10373.9 EER27270.1 - 5.3e-60 203.3 0.3 9.3e-60 202.5 0.1 1.5 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EER27270.1 - 2.6e-15 57.2 0.9 9.4e-15 55.5 0.4 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 PfkB PF00294.24 EER27271.1 - 1.2e-66 225.1 0.0 1.3e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF1770 PF08589.10 EER27272.1 - 2.2e-24 86.3 1.1 2.7e-24 86.0 1.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 EER27273.1 - 4.9e-07 29.1 0.1 1.4e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 GFO_IDH_MocA PF01408.22 EER27273.1 - 0.16 12.8 0.0 0.54 11.1 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Ribosomal_L2_C PF03947.18 EER27274.1 - 1.5e-41 141.5 5.8 2.8e-41 140.6 5.8 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EER27274.1 - 8e-15 54.6 0.1 2e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3093 PF11292.8 EER27274.1 - 0.15 12.3 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Ada_Zn_binding PF02805.16 EER27275.1 - 3.4e-29 100.7 8.5 6.5e-29 99.8 8.5 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EER27275.1 - 9.5e-09 35.1 0.0 2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EER27275.1 - 5.8e-05 23.3 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.7 EER27275.1 - 0.17 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 MarR family RNase_H PF00075.24 EER27276.1 - 3.6e-13 49.9 0.0 6.5e-13 49.1 0.0 1.2 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EER27276.1 - 9.3e-07 28.7 0.1 4.8e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Reverse transcriptase-like BAR PF03114.18 EER27277.1 - 2.2e-49 168.3 3.4 2.8e-49 167.9 3.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EER27277.1 - 1.8e-08 33.9 0.5 2.2e-08 33.6 0.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking OmpH PF03938.14 EER27277.1 - 0.11 12.9 9.0 0.3 11.4 8.3 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) HNH_2 PF13391.6 EER27278.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 HNH endonuclease SNF2_N PF00176.23 EER27279.1 - 3.1e-73 246.5 0.8 8.5e-73 245.1 0.8 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EER27279.1 - 1e-24 86.4 0.3 2.8e-24 85.0 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 EER27279.1 - 1.3e-21 77.1 1.4 1.3e-19 70.6 0.0 3.9 3 1 1 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.13 EER27279.1 - 1.5e-18 66.8 14.2 1.5e-18 66.8 14.2 3.8 4 0 0 4 4 4 1 HSA SnAC PF14619.6 EER27279.1 - 8.1e-15 55.2 2.2 8.1e-15 55.2 2.2 3.7 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.11 EER27279.1 - 8.5e-14 51.0 4.5 8.5e-14 51.0 4.5 3.1 3 0 0 3 3 3 1 QLQ ResIII PF04851.15 EER27279.1 - 5.9e-10 39.4 0.0 5.9e-10 39.4 0.0 2.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit CoA_binding PF02629.19 EER27280.1 - 3.7e-26 91.6 0.7 1.5e-25 89.7 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EER27280.1 - 6e-22 78.1 0.2 9.8e-22 77.4 0.2 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EER27280.1 - 3.2e-08 33.5 0.1 5.2e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EER27280.1 - 0.00059 20.3 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Radical_SAM_C PF16199.5 EER27281.1 - 4e-32 110.1 0.0 1.3e-31 108.4 0.0 1.9 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EER27281.1 - 4.2e-21 76.0 0.1 1.7e-20 74.1 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EER27281.1 - 9.6e-10 38.7 0.1 1.9e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER27281.1 - 1.2e-05 25.3 0.0 5.9e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER27281.1 - 0.18 12.3 0.1 0.4 11.2 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MARVEL PF01284.23 EER27282.1 - 0.0024 17.9 1.6 0.0027 17.8 1.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4064 PF13273.6 EER27282.1 - 0.006 16.8 0.1 0.0072 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) Pox_EPC_I2-L1 PF12575.8 EER27282.1 - 0.026 14.8 0.6 0.12 12.6 0.4 1.9 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 TMEMspv1-c74-12 PF11044.8 EER27282.1 - 0.029 14.4 0.3 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein UL41A PF17591.2 EER27282.1 - 0.05 13.7 0.7 0.13 12.4 0.0 1.8 1 1 1 2 2 2 0 Herpesvirus UL41A DUF4231 PF14015.6 EER27282.1 - 0.1 13.1 0.3 0.13 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) His_biosynth PF00977.21 EER27283.1 - 1.5e-31 109.6 0.0 1.8e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 EER27283.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.6 EER27284.1 - 3.3e-08 33.9 13.6 7.7e-08 32.7 13.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) STE PF02200.16 EER27285.1 - 1.6e-56 189.5 0.1 2.6e-56 188.8 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EER27285.1 - 2.9e-11 43.2 10.7 8.5e-07 29.1 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER27285.1 - 2e-08 34.4 7.9 0.00021 21.9 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EER27285.1 - 3.2e-08 33.6 3.6 3.2e-08 33.6 3.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EER27285.1 - 0.00073 19.5 4.1 0.0011 18.9 0.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger NOA36 PF06524.12 EER27285.1 - 0.0029 17.0 1.2 0.0049 16.2 1.2 1.3 1 0 0 1 1 1 1 NOA36 protein zf-C2H2_jaz PF12171.8 EER27285.1 - 0.015 15.6 2.2 0.098 13.0 0.0 2.9 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding FYDLN_acid PF09538.10 EER27285.1 - 0.024 15.3 2.2 0.024 15.3 2.2 1.9 2 0 0 2 2 1 0 Protein of unknown function (FYDLN_acid) zf-C2HC_2 PF13913.6 EER27285.1 - 0.094 12.6 0.4 0.094 12.6 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-TRAF PF02176.18 EER27285.1 - 0.13 13.0 2.4 0.23 12.2 2.4 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zinc_ribbon_9 PF14369.6 EER27285.1 - 0.14 12.4 0.3 0.34 11.2 0.3 1.6 1 0 0 1 1 1 0 zinc-ribbon zf-Di19 PF05605.12 EER27285.1 - 0.37 11.1 2.7 0.58 10.5 0.2 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 EER27285.1 - 2.8 7.8 7.8 20 5.0 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MFS_2 PF13347.6 EER27286.1 - 6.4e-11 41.5 4.6 6.4e-11 41.5 4.6 2.1 2 0 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 EER27286.1 - 0.0009 18.4 1.6 0.0017 17.4 1.6 1.4 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.21 EER27287.1 - 1.3e-72 244.7 37.6 1.7e-72 244.4 37.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pox_EPC_I2-L1 PF12575.8 EER27287.1 - 0.98 9.7 0.0 0.98 9.7 0.0 4.1 4 1 0 4 4 4 0 Poxvirus entry protein complex L1 and I2 ADH_N PF08240.12 EER27288.1 - 1.8e-30 105.0 0.4 3.1e-30 104.3 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER27288.1 - 1.7e-23 83.1 0.2 2.5e-23 82.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER27288.1 - 1e-07 33.0 0.0 1.8e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EER27288.1 - 0.027 13.8 0.3 0.039 13.2 0.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EER27288.1 - 0.034 13.5 0.2 0.064 12.6 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glucokinase PF02685.16 EER27288.1 - 0.038 13.0 0.1 0.058 12.4 0.1 1.3 1 0 0 1 1 1 0 Glucokinase SNF2_N PF00176.23 EER27289.1 - 3.7e-64 216.7 2.6 3.7e-64 216.7 2.6 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 EER27289.1 - 4.4e-47 159.8 21.3 4.4e-47 159.8 21.3 4.4 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 EER27289.1 - 8.7e-20 71.1 0.0 3.2e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER27289.1 - 1.4e-06 28.4 3.5 1.8e-06 28.1 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EER27289.1 - 0.00035 20.4 0.0 0.0011 18.7 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EER27289.1 - 0.031 13.4 0.0 0.031 13.4 0.0 3.1 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 Aminotran_1_2 PF00155.21 EER27290.1 - 2.8e-82 276.8 0.0 3.6e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EER27290.1 - 7.7e-07 28.0 0.0 1.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EER27290.1 - 5.1e-05 22.4 0.0 9.7e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EER27290.1 - 0.00057 19.3 0.1 0.0011 18.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family RNA_pol_I_A49 PF06870.12 EER27291.1 - 4.5e-73 246.3 0.1 5.3e-73 246.1 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Ribosomal_L41 PF05162.13 EER27292.1 - 1.3e-11 44.3 26.2 1.4e-11 44.3 26.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 GATase PF00117.28 EER27293.1 - 8.1e-48 162.7 0.0 1.1e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EER27293.1 - 3.6e-45 152.9 0.0 6.4e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EER27293.1 - 0.00048 20.0 0.6 0.012 15.4 0.5 2.6 1 1 0 1 1 1 1 Peptidase C26 Peptidase_S10 PF00450.22 EER27294.1 - 2e-91 307.5 3.7 8.6e-90 302.1 3.7 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase PARP PF00644.20 EER27295.1 - 1.9e-60 203.8 3.6 2.9e-60 203.2 0.0 2.9 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EER27295.1 - 4.9e-40 136.8 0.1 7.8e-40 136.1 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EER27295.1 - 1.9e-22 79.1 1.1 5.4e-22 77.7 1.1 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 EER27295.1 - 8.2e-12 45.3 0.1 2.6e-11 43.7 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EER27295.1 - 2.4e-09 37.5 0.8 9e-09 35.6 0.1 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EER27295.1 - 1.8e-08 34.2 0.1 4.2e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 EER27295.1 - 0.0048 17.1 0.0 0.014 15.7 0.0 1.9 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain SWIRM-assoc_2 PF16496.5 EER27295.1 - 0.23 10.3 10.4 0.071 12.0 5.2 2.2 2 0 0 2 2 2 0 SWIRM-associated domain at the N-terminal Ndc1_Nup PF09531.10 EER27295.1 - 0.68 8.5 5.3 0.85 8.2 5.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ysc84 PF04366.12 EER27296.1 - 7.9e-46 155.0 0.0 1.4e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator ETF PF01012.21 EER27297.1 - 8.5e-44 149.6 0.2 1e-43 149.4 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Flavodoxin_1 PF00258.25 EER27298.1 - 3.3e-31 108.4 0.0 1.2e-29 103.4 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EER27298.1 - 1.7e-29 103.0 0.0 2.9e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EER27298.1 - 3.7e-14 53.3 0.0 3.9e-13 50.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EER27298.1 - 0.00096 19.4 0.3 0.64 10.3 0.0 2.8 2 1 1 3 3 3 2 Flavodoxin domain Flavodoxin_3 PF12641.7 EER27298.1 - 0.06 13.0 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.8 EER27299.1 - 2.2e-66 224.4 3.8 2.6e-66 224.1 3.8 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF4687 PF15747.5 EER27300.1 - 0.59 10.6 2.7 11 6.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4687) MitMem_reg PF13012.6 EER27301.1 - 2e-10 41.1 0.1 1.7e-09 38.0 0.1 2.3 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EER27301.1 - 2.9e-08 33.7 0.0 5.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Phage-MuB_C PF09077.11 EER27301.1 - 0.06 13.2 0.7 3.2 7.7 0.2 2.4 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Solute_trans_a PF03619.16 EER27302.1 - 1.4e-94 316.6 23.9 1.6e-94 316.4 23.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF1422 PF07226.11 EER27302.1 - 3 7.9 9.3 4.1 7.4 2.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) TssN PF17555.2 EER27302.1 - 3.5 6.9 14.8 0.31 10.4 3.0 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN SAP PF02037.27 EER27303.1 - 7.1e-09 35.2 0.2 1.7e-08 34.0 0.2 1.7 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 EER27303.1 - 1.1e-08 35.3 0.0 1.1e-08 35.3 0.0 4.1 4 0 0 4 4 4 1 RNSP1-SAP18 binding (RSB) motif Pinin_SDK_memA PF04696.13 EER27303.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.5 3 1 0 3 3 3 0 pinin/SDK/memA/ protein conserved region Abhydrolase_1 PF00561.20 EER27304.1 - 1.7e-47 162.3 0.0 3e-47 161.4 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER27304.1 - 6.9e-05 23.5 5.8 0.00048 20.8 5.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EER27304.1 - 0.052 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein MFS_1 PF07690.16 EER27305.1 - 1.8e-23 83.1 30.3 7.9e-22 77.7 25.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily FeoB_C PF07664.12 EER27305.1 - 0.82 9.4 0.0 0.82 9.4 0.0 3.1 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus APH PF01636.23 EER27306.1 - 7.5e-06 26.0 0.0 1.4e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_M36 PF02128.15 EER27307.1 - 1.2e-162 541.3 1.6 1.6e-162 540.9 1.6 1.2 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EER27307.1 - 2.4e-19 68.9 3.2 5.2e-19 67.8 3.2 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Prenyltrans PF00432.21 EER27307.1 - 0.037 13.8 0.5 0.94 9.3 0.1 2.8 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat DUF4915 PF16261.5 EER27308.1 - 0.054 12.7 0.1 0.076 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4915) THOC2_N PF16134.5 EER27309.1 - 1.3e-255 849.9 0.0 2.5e-255 849.0 0.0 1.5 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EER27309.1 - 7.9e-104 347.1 0.0 1.4e-103 346.2 0.0 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EER27309.1 - 4.7e-31 106.7 0.3 1.9e-30 104.8 0.0 2.2 2 0 0 2 2 2 1 Transcription- and export-related complex subunit GFA PF04828.14 EER27310.1 - 3e-15 56.3 0.1 4.7e-15 55.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ADK_lid PF05191.14 EER27310.1 - 0.0036 17.2 0.8 0.032 14.2 0.1 2.4 2 1 0 2 2 2 1 Adenylate kinase, active site lid Vps5 PF09325.10 EER27311.1 - 1.3e-10 41.2 5.1 1.3e-10 41.2 5.1 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EER27311.1 - 1.9e-09 37.5 0.0 4.6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.9 EER27311.1 - 0.11 11.9 0.6 0.41 10.1 0.6 1.9 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein GTP_EFTU PF00009.27 EER27312.1 - 1.1e-52 178.5 0.0 1.9e-52 177.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EER27312.1 - 2e-26 91.9 0.1 1.3e-25 89.2 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 EER27312.1 - 4.1e-18 65.2 0.0 2.8e-09 36.9 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EER27312.1 - 6e-07 29.8 0.0 1.3e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EER27312.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 EER27312.1 - 0.00035 20.4 0.0 0.083 12.7 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G, domain IV RRM_1 PF00076.22 EER27314.1 - 6.7e-31 105.9 0.1 1.5e-15 56.7 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER27314.1 - 0.00017 21.6 0.0 0.14 12.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EER27314.1 - 0.00062 19.4 0.0 0.3 10.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EER27314.1 - 0.022 15.0 0.1 4.7 7.4 0.1 2.8 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4783 PF16022.5 EER27314.1 - 0.1 12.8 0.0 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) DbpA PF03880.15 EER27314.1 - 0.12 12.4 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain PRE_C2HC PF07530.11 EER27314.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Associated with zinc fingers Hid1 PF12722.7 EER27315.1 - 0.72 7.9 3.5 0.98 7.5 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF1631 PF07793.11 EER27315.1 - 9.1 4.6 9.8 36 2.6 9.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1631) MARVEL PF01284.23 EER27316.1 - 1.5e-06 28.3 10.9 3.6e-06 27.1 11.1 1.5 1 1 1 2 2 2 2 Membrane-associating domain DUF3246 PF11596.8 EER27316.1 - 0.17 11.3 1.6 1.5 8.2 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3246) TPMT PF05724.11 EER27317.1 - 7.1e-29 101.0 0.0 8.9e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.6 EER27317.1 - 5.1e-07 29.7 0.0 6.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER27317.1 - 2.8e-06 27.9 0.0 5e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER27317.1 - 3.4e-05 24.5 0.0 0.00023 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER27317.1 - 0.00013 21.8 0.0 0.00059 19.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER27317.1 - 0.00019 22.1 0.0 0.00032 21.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N2227 PF07942.12 EER27317.1 - 0.0056 15.9 0.0 0.0073 15.5 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein TehB PF03848.14 EER27317.1 - 0.011 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Glyco_transf_4 PF13439.6 EER27317.1 - 0.025 14.6 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 AdoMet_MTase PF07757.13 EER27317.1 - 0.17 12.2 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EER27317.1 - 0.22 11.5 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PALP PF00291.25 EER27318.1 - 1.4e-38 133.0 0.1 1.6e-38 132.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Homeobox_KN PF05920.11 EER27319.1 - 2.7e-17 62.4 0.6 7.2e-17 61.0 0.6 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EER27319.1 - 8.3e-10 38.4 0.7 1.9e-09 37.2 0.7 1.6 1 0 0 1 1 1 1 Homeodomain zf-C2H2 PF00096.26 EER27319.1 - 0.068 13.7 0.1 0.19 12.2 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Methyltransf_3 PF01596.17 EER27320.1 - 7.2e-11 41.7 0.0 8.7e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EER27320.1 - 2.3e-09 38.2 0.0 3.1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EER27320.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.5 1 1 0 1 1 1 0 Cephalosporin hydroxylase RNA12 PF10443.9 EER27320.1 - 0.013 14.3 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein Cation_ATPase_C PF00689.21 EER27321.1 - 0.75 9.5 9.8 1.2 8.9 0.4 2.4 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus HPP PF04982.13 EER27322.1 - 4.4e-39 133.4 5.9 4.4e-39 133.4 5.9 1.7 2 0 0 2 2 2 1 HPP family DUF599 PF04654.12 EER27322.1 - 0.091 12.2 1.4 0.8 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF599 OSTbeta PF15048.6 EER27322.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein ABC_tran PF00005.27 EER27323.1 - 1e-46 158.9 0.0 1.2e-22 80.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EER27323.1 - 3.2e-21 75.2 2.0 3.2e-21 75.2 2.0 3.2 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EER27323.1 - 6.3e-20 72.2 0.4 6.4e-05 22.9 0.0 4.5 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EER27323.1 - 7.5e-11 41.9 0.2 0.004 16.6 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EER27323.1 - 4.1e-08 34.0 2.1 0.026 15.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 EER27323.1 - 7.4e-08 32.5 0.1 0.014 15.1 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EER27323.1 - 9.6e-08 31.7 0.3 0.003 17.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EER27323.1 - 4.1e-06 26.8 0.1 0.0027 17.6 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_18 PF13238.6 EER27323.1 - 9.3e-06 26.2 0.2 0.15 12.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EER27323.1 - 3.2e-05 24.0 0.0 0.016 15.3 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EER27323.1 - 4.4e-05 23.9 0.0 0.022 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_27 PF13514.6 EER27323.1 - 5.9e-05 22.8 0.0 0.088 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EER27323.1 - 0.00014 22.2 0.1 0.07 13.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EER27323.1 - 0.00049 20.1 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_24 PF13479.6 EER27323.1 - 0.00062 19.5 1.2 2 8.1 0.0 3.7 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.22 EER27323.1 - 0.00079 19.8 0.8 1.8 9.0 0.0 3.1 3 0 0 3 3 3 2 RNA helicase Dynamin_N PF00350.23 EER27323.1 - 0.0011 19.1 2.3 2.1 8.4 0.0 4.2 3 1 1 4 4 4 1 Dynamin family AAA PF00004.29 EER27323.1 - 0.0022 18.4 0.0 1.4 9.3 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EER27323.1 - 0.0026 17.0 0.0 1.1 8.4 0.0 3.2 2 1 0 2 2 2 1 NB-ARC domain AAA_5 PF07728.14 EER27323.1 - 0.0028 17.7 0.1 1.1 9.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EER27323.1 - 0.0038 17.5 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EER27323.1 - 0.004 17.4 0.1 1.8 8.8 0.1 3.1 2 1 1 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EER27323.1 - 0.016 15.2 0.0 2.6 8.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EER27323.1 - 0.017 15.6 0.0 4.5 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EER27323.1 - 0.028 14.6 2.8 0.79 9.9 0.1 3.1 4 0 0 4 4 2 0 AAA domain MCM PF00493.23 EER27323.1 - 0.037 13.1 0.0 5.2 6.1 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_7 PF12775.7 EER27323.1 - 0.042 13.4 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 EER27323.1 - 0.047 13.3 0.1 1.1 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain Phage_tail_2 PF06199.11 EER27323.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Phage tail tube protein DUF3584 PF12128.8 EER27323.1 - 0.081 10.4 0.0 0.23 8.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rad17 PF03215.15 EER27323.1 - 0.1 12.5 0.0 17 5.3 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 EER27323.1 - 0.11 12.2 0.8 4.6 6.9 0.1 3.1 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EER27323.1 - 0.15 12.0 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 NTPase Cyclin_C_2 PF16899.5 EER27324.1 - 2.6e-35 120.9 0.0 6.8e-32 110.0 0.0 2.3 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EER27324.1 - 7.9e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain UvsW PF11637.8 EER27324.1 - 0.1 12.7 0.8 6.1 7.0 0.1 2.7 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW AAA PF00004.29 EER27325.1 - 5.5e-41 140.1 0.0 1.1e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER27325.1 - 3.9e-11 42.6 0.6 8.4e-11 41.5 0.6 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EER27325.1 - 2.1e-09 37.2 0.1 4.2e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EER27325.1 - 3.2e-06 27.4 0.0 6.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EER27325.1 - 7.1e-06 26.3 0.3 0.081 13.2 0.2 2.7 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 EER27325.1 - 5.4e-05 22.5 0.0 9.2e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EER27325.1 - 0.00017 21.6 0.1 0.0005 20.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EER27325.1 - 0.00088 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EER27325.1 - 0.0013 19.1 0.5 0.03 14.7 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EER27325.1 - 0.0057 16.9 0.0 0.0057 16.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EER27325.1 - 0.011 16.3 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EER27325.1 - 0.013 15.3 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 EER27325.1 - 0.015 14.6 0.1 0.04 13.1 0.1 1.7 1 1 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 EER27325.1 - 0.021 14.2 0.4 0.44 9.9 0.2 2.4 1 1 0 2 2 2 0 KaiC NACHT PF05729.12 EER27325.1 - 0.028 14.3 0.2 1.4 8.8 0.2 2.5 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 EER27325.1 - 0.029 13.8 0.9 0.92 8.9 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 EER27325.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EER27325.1 - 0.063 12.6 0.0 0.18 11.0 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EER27325.1 - 0.078 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EER27325.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EER27325.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EER27325.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Prot_ATP_OB_N PF17758.1 EER27325.1 - 0.13 11.9 0.4 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain Mg_chelatase PF01078.21 EER27325.1 - 0.14 11.5 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EER27325.1 - 0.14 12.4 0.4 0.36 11.1 0.4 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EER27325.1 - 0.19 11.5 0.5 0.49 10.1 0.5 1.7 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EER27325.1 - 0.2 11.3 2.3 0.4 10.4 0.5 2.3 2 1 0 2 2 2 0 AAA domain UQ_con PF00179.26 EER27326.1 - 1.9e-43 147.5 0.0 2.5e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EER27326.1 - 4.6e-07 29.5 0.0 1e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EER27326.1 - 0.00089 19.0 0.1 0.0031 17.2 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EER27326.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EER27326.1 - 0.21 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain WD40 PF00400.32 EER27327.1 - 1.1e-15 57.8 13.1 0.0021 18.8 0.3 5.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27327.1 - 3.9e-05 23.9 0.0 0.058 13.7 0.0 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 EER27327.1 - 0.07 13.1 0.2 5 7.2 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EER27327.1 - 0.072 12.0 0.2 3.7 6.4 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cwf_Cwc_15 PF04889.12 EER27327.1 - 2.6 7.7 9.9 0.23 11.2 4.4 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mg_trans_NIPA PF05653.14 EER27328.1 - 5.6e-61 206.2 10.3 3.2e-57 193.9 7.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EER27328.1 - 0.0098 16.1 0.3 0.0098 16.1 0.3 3.6 3 1 0 3 3 3 1 EamA-like transporter family CD20 PF04103.15 EER27328.1 - 0.081 13.0 4.1 1.1 9.3 0.2 2.8 3 0 0 3 3 3 0 CD20-like family BTP PF05232.12 EER27328.1 - 2.2 8.4 4.7 3.6 7.7 0.1 2.6 1 1 0 2 2 2 0 Chlorhexidine efflux transporter Lebercilin PF15619.6 EER27329.1 - 0.034 13.8 5.2 0.38 10.4 0.4 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease FlaC_arch PF05377.11 EER27329.1 - 0.16 12.4 1.9 0.21 12.0 0.5 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) KIAA1430 PF13879.6 EER27329.1 - 0.65 10.8 5.5 15 6.5 0.5 2.7 2 0 0 2 2 2 0 KIAA1430 homologue DUF1387 PF07139.11 EER27329.1 - 1.5 8.5 15.2 0.12 12.1 9.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) UPF0242 PF06785.11 EER27329.1 - 4.7 7.3 8.3 4.4 7.4 1.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DHR10 PF18595.1 EER27329.1 - 7.9 6.6 10.2 0.74 9.9 1.7 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain EI24 PF07264.11 EER27330.1 - 9.9e-16 58.5 17.0 1.4e-15 58.0 17.0 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) TMP_2 PF06791.13 EER27330.1 - 0.058 13.1 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF1189 PF06691.11 EER27330.1 - 0.059 12.9 3.2 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) VASt PF16016.5 EER27331.1 - 6.7e-34 117.5 0.0 1.2e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EER27331.1 - 7.4e-22 77.4 0.0 1.3e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DUF1501 PF07394.12 EER27331.1 - 0.61 9.1 3.4 0.99 8.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1501) adh_short PF00106.25 EER27332.1 - 7.4e-11 41.9 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER27332.1 - 4.4e-10 39.5 0.0 5.6e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER27332.1 - 0.029 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Cu_amine_oxid PF01179.20 EER27333.1 - 1.2e-160 534.9 0.1 1.5e-160 534.7 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EER27333.1 - 3.7e-19 69.0 0.3 3.5e-18 65.8 0.0 2.4 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EER27333.1 - 6.1e-15 55.2 0.0 1.1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF1 PF04857.20 EER27334.1 - 3.1e-23 82.5 0.0 1.9e-10 40.4 0.0 2.7 3 0 0 3 3 3 2 CAF1 family ribonuclease Sporozoite_P67 PF05642.11 EER27334.1 - 0.045 11.9 1.4 0.073 11.1 1.4 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ANAPC_CDC26 PF10471.9 EER27334.1 - 0.2 12.5 10.8 8.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Med3 PF11593.8 EER27334.1 - 2.2 7.4 18.5 0.52 9.4 2.5 3.1 3 0 0 3 3 3 0 Mediator complex subunit 3 fungal NDUF_B12 PF08122.12 EER27335.1 - 8.9e-26 89.7 0.3 1.3e-25 89.2 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.32 EER27336.1 - 4.5e-17 62.1 9.2 0.03 15.2 0.0 7.8 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27336.1 - 6e-06 26.5 0.0 0.0015 18.8 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EER27336.1 - 0.12 11.4 0.0 0.89 8.4 0.1 2.3 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Acetyltransf_10 PF13673.7 EER27337.1 - 2.8e-08 33.7 0.0 1.6e-06 28.1 0.0 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER27337.1 - 1e-07 32.2 0.0 2e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER27337.1 - 3.9e-07 30.3 0.1 9.4e-07 29.1 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 EER27337.1 - 1.6e-06 28.8 0.0 2.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER27337.1 - 0.0085 16.2 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EER27337.1 - 0.027 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.28 EER27338.1 - 3.2e-81 273.1 0.0 4.1e-81 272.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER27338.1 - 4.2e-14 53.3 0.0 9.6e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.6 EER27339.1 - 7.3e-25 88.3 0.0 3.7e-24 86.0 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CNH PF00780.22 EER27340.1 - 3e-68 230.4 0.0 4.6e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EER27340.1 - 2.3e-31 109.4 2.2 3.9e-31 108.7 1.4 1.9 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 EER27340.1 - 4.4e-13 49.5 0.0 2e-12 47.4 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EER27340.1 - 0.00034 21.1 0.0 0.0033 17.9 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 EER27340.1 - 0.0091 15.8 0.1 5.6 6.8 0.0 2.4 2 0 0 2 2 2 2 PH domain TORC_N PF12884.7 EER27340.1 - 1.8 9.4 7.1 26 5.7 0.6 4.0 3 0 0 3 3 3 0 Transducer of regulated CREB activity, N terminus RabGAP-TBC PF00566.18 EER27341.1 - 2.6e-46 158.0 0.0 4.2e-46 157.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 EER27341.1 - 0.00024 20.9 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 EER27341.1 - 0.01 15.7 0.3 0.01 15.7 0.3 2.9 3 0 0 3 3 3 0 EF-hand domain COMP PF11598.8 EER27341.1 - 0.14 12.6 0.0 0.31 11.6 0.0 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein ACC_epsilon PF13822.6 EER27343.1 - 1.8 9.3 7.1 2.6 8.8 2.5 3.3 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit adh_short_C2 PF13561.6 EER27344.1 - 2.1e-37 128.9 3.2 8.3e-37 127.0 3.2 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER27344.1 - 9.7e-29 100.2 0.7 1.7e-28 99.4 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER27344.1 - 3.7e-07 30.2 0.1 1.1e-06 28.7 0.2 1.7 2 0 0 2 2 2 1 KR domain DUF1772 PF08592.11 EER27345.1 - 0.0016 18.8 0.5 0.0058 16.9 0.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) BatA PF07584.11 EER27345.1 - 1 9.8 4.3 1.4 9.4 1.2 2.5 2 1 1 3 3 3 0 Aerotolerance regulator N-terminal AMP-binding PF00501.28 EER27347.1 - 2.5e-76 257.0 0.0 3.3e-76 256.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER27347.1 - 4.5e-14 53.2 0.6 9.3e-14 52.2 0.6 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MIOX PF05153.15 EER27348.1 - 1.5e-125 417.8 2.0 1.8e-125 417.5 2.0 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase DUF1796 PF08795.10 EER27348.1 - 0.032 14.2 0.2 0.047 13.6 0.2 1.3 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) HD PF01966.22 EER27348.1 - 0.059 13.6 0.1 0.7 10.1 0.0 2.4 2 0 0 2 2 2 0 HD domain RTA1 PF04479.13 EER27349.1 - 3.4e-78 262.0 1.8 5e-78 261.5 1.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Pex24p PF06398.11 EER27349.1 - 0.67 8.9 1.7 0.88 8.5 0.9 1.6 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Exo_endo_phos PF03372.23 EER27350.1 - 1e-09 38.2 0.0 5.3e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RTC PF01137.21 EER27351.1 - 2.9e-51 173.8 0.0 5.6e-51 172.9 0.0 1.4 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase SH3_9 PF14604.6 EER27354.1 - 1e-12 47.7 0.1 1.8e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EER27354.1 - 4.2e-12 45.5 0.1 7.4e-12 44.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain BAR PF03114.18 EER27354.1 - 5.8e-12 45.8 1.3 8.8e-12 45.2 1.3 1.2 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.17 EER27354.1 - 9.5e-10 38.0 0.1 1.5e-08 34.2 0.1 2.7 3 0 0 3 3 3 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 EER27354.1 - 7.4 7.2 15.4 0.46 11.0 8.9 2.3 2 0 0 2 2 2 0 Proline rich region of Caskin proteins DUF2439 PF10382.9 EER27355.1 - 1.7e-24 85.9 0.0 2.7e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Methyltransf_23 PF13489.6 EER27356.1 - 2e-13 50.5 0.0 3.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER27356.1 - 4.6e-09 36.8 0.0 1.4e-08 35.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER27356.1 - 8.7e-07 28.9 0.0 3.9e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER27356.1 - 9e-07 29.6 0.0 2.5e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER27356.1 - 9.9e-05 23.0 0.0 0.00026 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER27357.1 - 5.4e-17 62.1 0.0 8.7e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER27357.1 - 3.3e-12 46.9 0.0 1.3e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER27357.1 - 7.8e-10 39.3 0.0 5.1e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER27357.1 - 2e-08 34.2 0.1 3.8e-07 30.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER27357.1 - 9.5e-07 29.5 0.0 5.5e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER27357.1 - 0.00026 20.4 0.0 0.0057 16.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EER27357.1 - 0.0032 17.2 0.0 0.0054 16.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 EER27357.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EER27357.1 - 0.058 12.9 0.0 0.24 10.9 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 EER27357.1 - 0.062 12.8 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.19 EER27357.1 - 0.16 11.7 0.0 1.1 9.0 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 EER27358.1 - 3.9e-58 197.3 0.0 4.8e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ku PF02735.16 EER27359.1 - 6.1e-44 150.2 0.0 1.2e-43 149.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EER27359.1 - 1.4e-33 116.5 0.0 2.3e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EER27359.1 - 5e-27 94.4 2.0 1.3e-26 93.1 2.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EER27359.1 - 7.7e-11 41.5 0.0 1.6e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 SAP domain TAF8_C PF10406.9 EER27359.1 - 0.055 14.0 0.0 0.25 11.9 0.0 2.1 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term CMAS PF02353.20 EER27360.1 - 0.007 15.7 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MIB_HERC2 PF06701.13 EER27361.1 - 0.11 12.7 0.1 9.5 6.6 0.0 2.9 3 0 0 3 3 3 0 Mib_herc2 zf-CCCH PF00642.24 EER27362.1 - 2.4e-08 33.7 2.4 4.7e-08 32.7 2.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 EER27362.1 - 4.7e-08 32.9 7.1 9.5e-08 31.9 7.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EER27362.1 - 5.8e-08 32.4 9.1 1.1e-07 31.6 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER27362.1 - 1.1e-07 31.6 6.2 2.1e-07 30.7 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER27362.1 - 2.9e-07 30.2 11.0 5.3e-07 29.4 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EER27362.1 - 6.6e-06 26.2 4.2 1.6e-05 24.9 4.2 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 EER27362.1 - 7e-06 25.9 9.7 1.2e-05 25.1 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EER27362.1 - 1.5e-05 25.2 7.5 2.7e-05 24.4 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 EER27362.1 - 4.5e-05 23.4 5.3 9.3e-05 22.4 5.3 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_4 PF15227.6 EER27362.1 - 0.00063 19.9 9.1 0.0014 18.7 9.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EER27362.1 - 0.0054 16.5 2.6 0.011 15.6 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EER27362.1 - 0.013 15.4 6.5 0.024 14.5 6.5 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 EER27362.1 - 0.013 15.2 2.0 0.013 15.2 2.0 2.0 2 0 0 2 2 1 0 CCCH-type zinc finger zf-rbx1 PF12678.7 EER27362.1 - 0.079 13.3 4.6 0.16 12.3 4.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EER27362.1 - 0.26 11.0 3.5 0.56 9.9 3.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-CCCH_2 PF14608.6 EER27362.1 - 3.3 8.3 6.8 0.43 11.1 2.5 1.8 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger Mcp5_PH PF12814.7 EER27363.1 - 7e-45 152.1 0.2 1.5e-44 151.0 0.2 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EER27363.1 - 0.00039 20.9 0.0 0.0012 19.3 0.0 1.9 1 0 0 1 1 1 1 PH domain Jnk-SapK_ap_N PF09744.9 EER27363.1 - 0.9 9.8 41.6 0.17 12.1 10.5 4.6 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 Herpes_UL25 PF01499.16 EER27363.1 - 2.3 6.6 12.9 0.067 11.7 6.2 1.9 2 0 0 2 2 2 0 Herpesvirus UL25 family DUF1664 PF07889.12 EER27363.1 - 4.1 7.4 15.2 1.8 8.6 3.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) SKG6 PF08693.10 EER27364.1 - 2.9e-08 33.0 0.2 5.8e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 EER27364.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MFS_1 PF07690.16 EER27365.1 - 1.1e-24 87.0 36.2 5.1e-24 84.9 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferrochelatase PF00762.19 EER27366.1 - 7.4e-97 324.2 0.0 8.6e-97 324.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MP PF01107.18 EER27366.1 - 0.24 11.0 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Viral movement protein (MP) PPR PF01535.20 EER27367.1 - 7.6e-07 29.0 3.6 0.036 14.3 0.1 6.0 5 0 0 5 5 5 2 PPR repeat PPR_2 PF13041.6 EER27367.1 - 7e-06 26.1 1.9 0.22 11.7 0.1 5.0 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 EER27367.1 - 2.3e-05 24.4 0.2 0.0015 18.6 0.1 2.6 2 0 0 2 2 2 1 Pentatricopeptide repeat domain DUF1028 PF06267.12 EER27367.1 - 0.26 11.0 0.9 0.56 10.0 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF1028) SE PF08491.10 EER27368.1 - 2.2e-96 322.2 0.0 2.7e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EER27368.1 - 4.8e-09 35.9 0.0 1.4e-08 34.4 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EER27368.1 - 2.7e-08 33.8 0.1 3.7e-06 26.8 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EER27368.1 - 1e-06 28.2 1.4 4.9e-05 22.6 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EER27368.1 - 3.6e-05 23.9 0.5 6.8e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EER27368.1 - 0.00034 19.8 0.6 0.00075 18.7 0.6 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EER27368.1 - 0.00038 19.6 0.4 0.00071 18.7 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EER27368.1 - 0.00041 19.7 0.1 0.00065 19.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EER27368.1 - 0.00069 19.1 0.2 0.0011 18.5 0.2 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EER27368.1 - 0.0015 17.3 0.5 0.0025 16.6 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EER27368.1 - 0.0016 17.7 0.1 0.0054 16.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 EER27368.1 - 0.058 14.0 0.5 0.13 12.8 0.1 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EER27368.1 - 0.096 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EER27368.1 - 0.22 10.7 0.5 0.35 10.1 0.5 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EER27368.1 - 0.28 10.0 0.6 0.64 8.8 0.3 1.6 1 1 0 2 2 2 0 Tryptophan halogenase PAP_assoc PF03828.19 EER27369.1 - 1.1e-16 60.7 0.0 2.7e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EER27369.1 - 7.2e-07 29.4 0.0 1.4e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EER27369.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase CALM_bind PF16025.5 EER27370.1 - 1.4 9.4 5.6 4.4 7.9 5.6 1.8 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding SLC35F PF06027.12 EER27371.1 - 2.2e-102 342.6 23.9 2.6e-102 342.4 23.9 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EER27371.1 - 2e-09 36.9 4.5 2.9e-09 36.3 4.5 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EER27371.1 - 7.5e-08 32.6 33.0 0.00032 20.9 11.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF2207 PF09972.9 EER27371.1 - 8.5 5.0 17.7 0.47 9.2 3.4 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) SMK-1 PF04802.15 EER27372.1 - 2.5e-77 259.0 0.3 2.5e-77 259.0 0.3 1.5 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 LIDHydrolase PF10230.9 EER27373.1 - 7.4e-63 212.6 0.0 1.1e-52 179.2 0.0 2.7 2 1 0 2 2 2 2 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EER27373.1 - 0.00013 21.4 0.0 0.00024 20.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EER27373.1 - 0.0012 18.6 0.0 0.0051 16.5 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EER27373.1 - 0.0019 18.8 0.0 0.003 18.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 EER27373.1 - 0.0029 17.2 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EER27373.1 - 0.025 14.2 0.0 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_9 PF10081.9 EER27373.1 - 0.054 12.6 0.1 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta-hydrolase family Thioesterase PF00975.20 EER27373.1 - 0.056 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.15 EER27373.1 - 0.081 12.1 0.0 0.64 9.1 0.0 2.0 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DCP1 PF06058.13 EER27374.1 - 5.7e-30 103.6 0.0 8.2e-30 103.1 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.23 EER27375.1 - 3.4e-06 26.7 0.0 7.7e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EXOSC1 PF10447.9 EER27375.1 - 0.0015 19.1 0.1 0.01 16.4 0.0 2.3 2 0 0 2 2 2 1 Exosome component EXOSC1/CSL4 RhoGAP PF00620.27 EER27375.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 RhoGAP domain HSBP1 PF06825.12 EER27376.1 - 0.00032 20.5 0.8 0.0079 16.0 0.0 2.4 2 0 0 2 2 2 1 Heat shock factor binding protein 1 HOOK PF05622.12 EER27376.1 - 0.0059 14.8 2.2 0.0076 14.5 2.2 1.1 1 0 0 1 1 1 1 HOOK protein Fib_alpha PF08702.10 EER27376.1 - 0.069 13.3 1.4 0.12 12.5 1.4 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 EER27376.1 - 0.08 13.2 2.6 1.8 8.9 0.0 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain Baculo_PEP_C PF04513.12 EER27376.1 - 0.24 11.4 1.1 0.53 10.3 1.1 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2730 PF10805.8 EER27376.1 - 0.73 10.0 3.5 3.3 7.9 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 EER27376.1 - 1.3 9.5 3.5 1.4 9.4 1.9 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) STE3 PF02076.15 EER27377.1 - 4e-93 311.8 15.3 4.6e-93 311.6 15.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.25 EER27378.1 - 6.6e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Single-strand binding protein family Erf4 PF10256.9 EER27379.1 - 5.8e-39 132.8 0.0 7.9e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Adap_comp_sub PF00928.21 EER27380.1 - 1.7e-84 283.3 0.0 2.1e-84 283.0 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EER27380.1 - 0.00011 22.1 0.2 0.00019 21.3 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EER27380.1 - 0.034 13.6 0.1 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain Pkinase PF00069.25 EER27381.1 - 1.7e-59 201.3 0.1 5.2e-54 183.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER27381.1 - 2.5e-27 95.8 0.0 7.4e-25 87.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 EER27381.1 - 5.1e-11 42.8 0.0 1.3e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EER27381.1 - 2.3e-05 23.4 0.1 0.00015 20.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EER27381.1 - 0.00011 22.5 0.0 0.0009 19.5 0.0 2.5 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EER27381.1 - 0.00021 20.7 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EER27381.1 - 0.00056 19.3 1.0 0.0012 18.3 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER27381.1 - 0.0013 18.7 0.1 0.0025 17.8 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EER27381.1 - 0.014 14.4 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain FHA_2 PF17913.1 EER27381.1 - 0.052 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 FHA domain YrbL-PhoP_reg PF10707.9 EER27381.1 - 0.052 13.1 0.7 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.11 EER27381.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Myb_DNA-bind_6 PF13921.6 EER27382.1 - 0.0012 19.1 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain PBP1_TM PF14812.6 EER27382.1 - 0.031 14.7 3.5 0.031 14.7 3.5 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myb_DNA-binding PF00249.31 EER27382.1 - 0.12 12.6 0.2 0.24 11.6 0.2 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain bVLRF1 PF18826.1 EER27384.1 - 1.3e-60 203.6 0.0 2.8e-60 202.5 0.0 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EER27384.1 - 0.00057 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER27384.1 - 0.0028 18.0 0.0 0.0072 16.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.30 EER27384.1 - 0.0056 17.1 0.7 0.015 15.7 0.7 1.7 1 0 0 1 1 1 1 Ankyrin repeat Gluconate_2-dh3 PF13618.6 EER27384.1 - 0.021 15.0 1.3 0.53 10.5 0.1 2.6 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 zf-C2H2_jaz PF12171.8 EER27384.1 - 0.039 14.2 0.9 0.079 13.3 0.9 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EER27384.1 - 0.07 13.5 0.2 0.17 12.2 0.2 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EER27384.1 - 0.092 13.6 0.5 0.23 12.4 0.5 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Ank_2 PF12796.7 EER27384.1 - 0.13 12.8 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-met PF12874.7 EER27384.1 - 0.16 12.4 0.7 0.33 11.4 0.7 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type ABC_membrane PF00664.23 EER27385.1 - 1.2e-80 271.1 31.2 2.3e-44 152.1 13.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EER27385.1 - 5.1e-51 172.8 0.0 6.3e-29 101.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EER27385.1 - 1.3e-11 44.4 2.6 0.00034 20.1 0.1 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EER27385.1 - 1.2e-06 28.5 0.2 0.042 13.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EER27385.1 - 2.5e-06 28.0 0.3 0.0043 17.4 0.4 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EER27385.1 - 5.3e-05 23.2 0.0 0.018 15.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EER27385.1 - 0.00018 21.2 0.0 0.44 10.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EER27385.1 - 0.00035 21.1 0.0 0.026 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EER27385.1 - 0.00053 19.7 1.0 0.3 10.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EER27385.1 - 0.00095 19.3 0.2 0.13 12.4 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 EER27385.1 - 0.0018 18.1 1.6 0.15 11.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 EER27385.1 - 0.0073 16.4 0.3 1.3 9.1 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 EER27385.1 - 0.015 15.6 1.1 4.6 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 EER27385.1 - 0.035 13.7 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EER27385.1 - 0.042 13.6 0.1 0.38 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.6 EER27385.1 - 0.051 13.2 0.2 4.4 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EER27385.1 - 0.053 13.2 1.4 5.8 6.6 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Roc PF08477.13 EER27385.1 - 0.15 12.2 0.1 24 5.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EER27385.1 - 0.17 12.3 0.0 9 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EER27385.1 - 0.2 12.1 0.8 4.6 7.7 0.1 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF999 PF06198.11 EER27385.1 - 0.31 11.0 1.7 0.79 9.7 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF999) NACHT PF05729.12 EER27385.1 - 0.52 10.2 4.5 2.4 8.1 0.1 3.1 3 0 0 3 3 3 0 NACHT domain DUF2841 PF11001.8 EER27386.1 - 8.2e-53 177.7 0.5 1.3e-52 177.1 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) FAM47 PF14642.6 EER27386.1 - 0.18 11.3 1.7 0.39 10.2 0.7 1.8 2 0 0 2 2 2 0 FAM47 family SAC3_GANP PF03399.16 EER27387.1 - 1.1e-102 343.4 2.1 1.1e-102 343.4 2.1 1.9 2 0 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EER27387.1 - 7e-06 26.1 1.0 1.5e-05 25.0 0.2 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family HC2 PF07382.11 EER27387.1 - 0.17 12.0 19.9 0.33 11.0 19.9 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 PAM2 PF07145.15 EER27387.1 - 0.17 11.7 5.8 0.097 12.4 0.6 2.8 2 0 0 2 2 2 0 Ataxin-2 C-terminal region PGAP1 PF07819.13 EER27388.1 - 4.8e-08 33.0 0.0 1.2e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.12 EER27388.1 - 2.5e-05 24.3 0.0 5.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.7 EER27388.1 - 3.9e-05 24.4 0.0 6.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EER27388.1 - 0.0025 17.4 0.0 0.0055 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_14 PF13173.6 EER27388.1 - 0.0061 16.6 0.0 0.11 12.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EER27388.1 - 0.01 16.3 0.0 0.039 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain LCAT PF02450.15 EER27388.1 - 0.018 14.2 0.0 0.072 12.2 0.0 1.9 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase AAA_22 PF13401.6 EER27388.1 - 0.08 13.2 0.0 1.6 9.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.8 EER27388.1 - 0.085 12.1 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 RNA_helicase PF00910.22 EER27388.1 - 0.18 12.2 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase CN_hydrolase PF00795.22 EER27389.1 - 3.3e-10 39.7 0.0 3.8e-09 36.3 0.0 2.4 2 1 0 3 3 3 1 Carbon-nitrogen hydrolase HLH PF00010.26 EER27390.1 - 1e-13 51.0 0.8 2e-13 50.1 0.8 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Mobilization_B PF17511.2 EER27390.1 - 0.038 14.4 1.3 0.078 13.3 1.3 1.5 1 0 0 1 1 1 0 Mobilization protein B HMGL-like PF00682.19 EER27390.1 - 0.2 11.1 2.0 7.9 5.9 0.1 2.2 2 0 0 2 2 2 0 HMGL-like PLC-beta_C PF08703.10 EER27390.1 - 0.29 11.1 4.5 0.74 9.8 4.5 1.6 1 1 0 1 1 1 0 PLC-beta C terminal Sec8_exocyst PF04048.14 EER27391.1 - 3e-40 137.4 0.5 2.5e-39 134.4 0.1 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EER27391.1 - 1.3e-08 34.5 0.0 3.7e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Zw10 PF06248.13 EER27391.1 - 0.0041 15.8 0.0 0.0076 14.9 0.0 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Creatinase_N_2 PF16189.5 EER27392.1 - 7.7e-56 188.6 0.0 1.9e-54 184.1 0.0 2.5 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EER27392.1 - 1.3e-42 145.9 0.0 2e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EER27392.1 - 1.9e-22 80.3 0.0 1.1e-17 64.9 0.0 2.8 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EER27392.1 - 2.9e-21 75.3 0.6 1.3e-20 73.2 1.0 2.1 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Importin_rep_3 PF18806.1 EER27393.1 - 0.00017 21.6 0.0 0.13 12.3 0.0 3.1 2 0 0 2 2 2 2 Importin 13 repeat Importin_rep PF18773.1 EER27393.1 - 0.00077 19.1 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 Importin 13 repeat IBN_N PF03810.19 EER27393.1 - 0.046 13.6 0.1 0.13 12.2 0.1 1.8 1 0 0 1 1 1 0 Importin-beta N-terminal domain Bcl-2 PF00452.19 EER27393.1 - 0.09 13.5 0.2 9.8 6.9 0.0 3.7 3 1 0 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family SOR_SNZ PF01680.17 EER27394.1 - 1.5e-108 361.3 4.5 2.4e-108 360.7 4.5 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EER27394.1 - 2.4e-10 40.1 5.0 7.8e-08 31.9 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EER27394.1 - 0.0002 20.6 0.1 0.14 11.2 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EER27394.1 - 0.0021 17.5 0.1 0.023 14.2 0.0 2.3 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.14 EER27394.1 - 0.0042 16.3 0.4 0.097 11.9 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 EER27394.1 - 0.0051 16.0 0.0 0.19 10.8 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase TMP-TENI PF02581.17 EER27394.1 - 0.011 15.0 0.6 0.43 9.9 0.0 3.0 3 0 0 3 3 3 0 Thiamine monophosphate synthase OMPdecase PF00215.24 EER27394.1 - 0.012 15.2 0.1 0.4 10.2 0.0 2.4 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.15 EER27394.1 - 0.017 14.6 3.6 0.48 9.7 0.0 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase TetR_C_27 PF17935.1 EER27394.1 - 0.017 15.1 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MttA_Hcf106 PF02416.16 EER27394.1 - 0.13 11.6 0.1 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 mttA/Hcf106 family Aegerolysin PF06355.13 EER27396.1 - 6.7e-42 142.7 0.2 7.5e-42 142.5 0.2 1.0 1 0 0 1 1 1 1 Aegerolysin zf-CDGSH PF09360.10 EER27396.1 - 0.0049 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Amidinotransf PF02274.17 EER27397.1 - 3.4e-12 46.1 0.0 0.00032 19.9 0.0 3.9 3 1 0 3 3 3 3 Amidinotransferase p450 PF00067.22 EER27398.1 - 1.8e-59 201.8 0.0 2.4e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SH3_16 PF18348.1 EER27398.1 - 0.042 13.6 0.1 0.08 12.7 0.1 1.4 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain p450 PF00067.22 EER27399.1 - 4.2e-33 114.8 0.0 5.6e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FUN14 PF04930.15 EER27400.1 - 2.5e-08 34.2 0.5 4.4e-08 33.4 0.5 1.4 1 0 0 1 1 1 1 FUN14 family ORC2 PF04084.14 EER27401.1 - 7.9e-118 393.2 0.0 9.4e-118 392.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ArgJ PF01960.18 EER27402.1 - 2.2e-149 497.3 0.0 2.4e-149 497.1 0.0 1.0 1 0 0 1 1 1 1 ArgJ family SecY PF00344.20 EER27403.1 - 9.6e-74 248.4 5.7 1.2e-73 248.1 5.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EER27403.1 - 2.2e-17 62.6 0.3 6e-17 61.2 0.3 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p GFA PF04828.14 EER27404.1 - 7.6e-12 45.4 2.0 7.6e-12 45.4 2.0 2.2 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ank_2 PF12796.7 EER27405.1 - 2.1e-25 89.1 10.0 2.3e-12 47.3 4.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EER27405.1 - 9.5e-24 82.8 9.8 0.00014 22.2 0.4 5.4 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EER27405.1 - 1.3e-23 83.0 8.7 1.1e-07 32.3 0.3 3.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EER27405.1 - 5.4e-22 77.6 8.3 4.6e-07 30.0 0.5 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER27405.1 - 1.6e-20 71.0 3.3 0.00049 20.3 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat DUF2520 PF10728.9 EER27405.1 - 0.028 14.2 3.3 0.047 13.5 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) CARM1 PF11531.8 EER27405.1 - 0.13 12.5 0.7 2.5 8.3 0.2 2.8 1 1 3 4 4 4 0 Coactivator-associated arginine methyltransferase 1 N terminal Imm7 PF15585.6 EER27405.1 - 0.31 11.3 2.9 1.1 9.6 0.8 2.5 1 1 2 3 3 3 0 Immunity protein 7 VWA_3_C PF18571.1 EER27405.1 - 1.3 8.9 5.6 17 5.4 0.0 4.3 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain MUG113 PF13455.6 EER27406.1 - 3e-21 75.9 0.4 3e-21 75.9 0.4 2.6 2 1 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EER27406.1 - 1.4e-20 73.8 0.1 1.4e-20 73.8 0.1 2.9 4 1 0 4 4 4 1 T5orf172 domain VIR_N PF15912.5 EER27406.1 - 0.79 9.3 8.5 1.5 8.4 8.5 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal ABC_membrane PF00664.23 EER27407.1 - 1.6e-101 339.6 36.3 7.1e-52 176.7 16.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EER27407.1 - 9.1e-67 223.8 0.0 3.5e-32 111.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EER27407.1 - 3.2e-15 56.2 0.0 6.3e-05 22.5 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EER27407.1 - 8.3e-07 29.5 2.9 0.032 14.6 0.1 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EER27407.1 - 9e-07 28.5 1.6 0.0069 16.1 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EER27407.1 - 1.1e-06 28.6 0.1 0.089 12.7 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EER27407.1 - 3.1e-06 27.5 0.3 0.091 13.0 0.1 3.5 3 1 0 3 3 2 2 AAA domain AAA_21 PF13304.6 EER27407.1 - 1e-05 25.5 0.7 0.12 12.1 0.0 3.6 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EER27407.1 - 1.7e-05 24.6 4.9 0.2 11.3 0.0 4.3 4 1 0 4 4 4 2 AAA domain AAA PF00004.29 EER27407.1 - 7.5e-05 23.2 2.1 10 6.5 0.0 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EER27407.1 - 9.8e-05 22.3 0.2 0.036 14.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EER27407.1 - 0.00012 21.7 0.0 0.076 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EER27407.1 - 0.0002 21.1 0.3 0.42 10.2 0.0 3.0 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_15 PF13175.6 EER27407.1 - 0.0002 21.2 1.1 0.4 10.3 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_7 PF12775.7 EER27407.1 - 0.00031 20.3 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region ABC_ATPase PF09818.9 EER27407.1 - 0.00041 19.3 2.8 0.067 12.0 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_18 PF13238.6 EER27407.1 - 0.00045 20.8 0.2 1.3 9.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 EER27407.1 - 0.00086 19.3 0.5 2 8.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 EER27407.1 - 0.0031 16.8 0.1 3.9 6.7 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin AAA_33 PF13671.6 EER27407.1 - 0.0056 16.9 0.6 3.8 7.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EER27407.1 - 0.0062 16.3 0.1 2.8 7.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EER27407.1 - 0.014 15.6 1.1 1.6 9.0 0.1 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EER27407.1 - 0.015 15.5 4.4 4.6 7.5 0.3 4.0 3 2 0 3 3 3 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EER27407.1 - 0.019 15.4 0.1 3.8 7.9 0.0 3.0 2 0 0 2 2 2 0 RNA helicase PRK PF00485.18 EER27407.1 - 0.032 14.0 0.0 6.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_23 PF13476.6 EER27407.1 - 0.034 14.6 3.6 2.7 8.4 0.2 3.1 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 EER27407.1 - 0.099 12.7 0.9 26 4.9 0.0 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase G-alpha PF00503.20 EER27407.1 - 0.11 11.6 0.0 16 4.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit ATP_bind_1 PF03029.17 EER27407.1 - 0.16 11.8 0.1 3.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cu_bind_CorA PF18252.1 EER27407.1 - 0.17 11.5 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Copper(I)-binding protein CorA CDC45 PF02724.14 EER27407.1 - 0.23 9.7 1.1 0.43 8.8 1.1 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF87 PF01935.17 EER27407.1 - 2 8.4 5.2 16 5.5 0.1 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain Ribosomal_L39 PF00832.20 EER27408.1 - 6.3e-22 76.9 9.4 7.3e-22 76.7 9.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.19 EER27409.1 - 2.9e-28 97.7 0.5 4.8e-28 97.0 0.5 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EER27409.1 - 2.2e-24 85.4 0.1 5.3e-24 84.2 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain SERTA PF06031.13 EER27409.1 - 0.17 11.6 0.1 1 9.1 0.0 2.2 3 0 0 3 3 3 0 SERTA motif Glyco_transf_22 PF03901.17 EER27410.1 - 1.3e-50 172.9 15.9 1.5e-28 100.2 2.7 2.1 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family UBA PF00627.31 EER27411.1 - 3.7e-25 87.4 4.5 4.4e-13 48.8 0.3 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 EER27411.1 - 2.4e-24 84.8 17.8 4.2e-24 84.1 17.8 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 EER27411.1 - 3.9e-22 77.8 0.2 6.5e-22 77.1 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EER27411.1 - 5.9e-08 32.4 0.4 1e-07 31.7 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EER27411.1 - 0.00072 19.3 0.0 1.3 8.9 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Ubiquitin_5 PF18037.1 EER27411.1 - 0.01 16.2 0.2 0.018 15.4 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Ubiquitin_2 PF14560.6 EER27411.1 - 0.018 15.5 0.1 0.043 14.3 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EER27411.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EER27411.1 - 0.081 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CCDC53 PF10152.9 EER27411.1 - 0.8 10.1 7.7 5.6 7.4 0.4 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex SOG2 PF10428.9 EER27411.1 - 1.3 8.2 4.4 1.5 8.0 4.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3391 PF11871.8 EER27411.1 - 7.3 7.1 8.9 24 5.5 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3391) F-box PF00646.33 EER27412.1 - 0.054 13.4 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain Aminotran_1_2 PF00155.21 EER27413.1 - 3.8e-44 151.3 0.0 5.2e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EER27413.1 - 5.2e-09 35.5 0.0 8.7e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EER27413.1 - 2e-06 26.6 0.0 2.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EER27413.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase eIF-6 PF01912.18 EER27415.1 - 1.6e-80 269.1 0.5 2.2e-80 268.7 0.5 1.2 1 0 0 1 1 1 1 eIF-6 family HupE_UreJ PF04955.12 EER27415.1 - 0.077 12.5 0.2 0.15 11.6 0.2 1.4 1 0 0 1 1 1 0 HupE / UreJ protein SRI PF08236.11 EER27416.1 - 4.4e-21 74.9 14.9 1.3e-20 73.3 14.9 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EER27416.1 - 5.7e-18 65.9 0.6 5.7e-18 65.9 0.6 3.7 3 2 0 3 3 3 1 SET domain AWS PF17907.1 EER27416.1 - 3e-10 39.9 10.3 3e-10 39.9 10.3 2.4 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 EER27416.1 - 9.4e-05 22.4 1.2 0.00017 21.5 0.1 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 EER27416.1 - 0.00074 19.6 1.3 0.0025 17.9 1.3 2.0 1 0 0 1 1 1 1 WW domain CENP-X PF09415.10 EER27416.1 - 0.18 12.1 1.7 0.6 10.5 1.7 1.9 1 0 0 1 1 1 0 CENP-S associating Centromere protein X BAR PF03114.18 EER27418.1 - 1.1e-59 202.0 3.8 1.4e-59 201.7 3.8 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EER27418.1 - 0.0059 17.3 0.5 0.028 15.1 0.0 2.4 3 2 0 3 3 3 1 CP12 domain SVIP PF15811.5 EER27418.1 - 3.3 8.2 7.4 0.23 11.9 1.1 2.3 2 1 0 2 2 2 0 Small VCP/p97-interacting protein BRE1 PF08647.11 EER27418.1 - 5.8 7.1 8.2 16 5.6 3.9 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Pkinase PF00069.25 EER27419.1 - 3.8e-57 193.6 0.0 1.3e-50 172.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER27419.1 - 6.6e-37 127.2 0.0 7.1e-35 120.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EER27419.1 - 8.2e-07 28.6 0.0 4.3e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EER27419.1 - 0.0023 17.9 0.0 0.0093 15.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EER27419.1 - 0.014 14.2 0.0 0.014 14.2 0.0 2.0 3 0 0 3 3 3 0 Fungal protein kinase Sybindin PF04099.12 EER27420.1 - 3.3e-26 91.9 0.0 4.3e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EER27420.1 - 0.0023 18.1 0.1 0.0031 17.6 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 EER27421.1 - 1.7e-51 175.1 0.0 2.4e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27421.1 - 2.4e-29 102.4 0.0 3.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER27421.1 - 0.0049 16.2 0.1 0.011 15.1 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EER27421.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER27421.1 - 0.13 12.2 0.6 1.7 8.5 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Methyltransf_23 PF13489.6 EER27422.1 - 5.1e-11 42.7 0.0 8.8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER27422.1 - 1.1e-07 32.4 0.0 2.8e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER27422.1 - 1e-05 25.4 0.0 2.8e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER27422.1 - 4e-05 24.3 0.0 0.00037 21.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER27422.1 - 0.012 14.9 0.0 0.036 13.4 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EER27422.1 - 0.016 14.7 0.0 0.22 11.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 EER27422.1 - 0.023 15.3 0.0 0.055 14.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EER27422.1 - 0.061 12.6 0.0 1.2 8.4 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase domain DUF4447 PF14590.6 EER27422.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) PhyH PF05721.13 EER27423.1 - 6.7e-09 36.3 0.1 2.5e-08 34.4 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Brix PF04427.18 EER27424.1 - 2.2e-24 86.6 0.0 3.7e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain Neur_chan_memb PF02932.16 EER27424.1 - 0.85 9.6 2.9 1.4 8.9 2.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HGTP_anticodon PF03129.20 EER27425.1 - 8.2e-21 74.0 0.0 8.2e-21 74.0 0.0 2.5 3 1 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EER27425.1 - 7.7e-09 35.8 0.1 7.6e-08 32.5 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) EF-hand_5 PF13202.6 EER27425.1 - 0.16 11.5 0.4 0.47 10.0 0.4 1.9 1 0 0 1 1 1 0 EF hand Pkinase PF00069.25 EER27427.1 - 5.8e-69 232.4 0.5 5.2e-68 229.3 0.5 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27427.1 - 6.8e-52 176.3 0.0 1.3e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EER27427.1 - 9.7e-24 83.5 1.7 4.4e-23 81.4 0.0 2.8 3 0 0 3 3 3 1 P21-Rho-binding domain PH_11 PF15413.6 EER27427.1 - 5.1e-16 59.0 0.5 1.2e-15 57.8 0.5 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EER27427.1 - 3.4e-06 27.5 0.2 8.3e-06 26.3 0.2 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EER27427.1 - 1.8e-05 24.2 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EER27427.1 - 2.2e-05 23.5 0.0 2.2e-05 23.5 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase Haspin_kinase PF12330.8 EER27427.1 - 7.5e-05 21.8 0.4 0.00021 20.4 0.4 1.7 1 1 0 1 1 1 1 Haspin like kinase domain KIND PF16474.5 EER27427.1 - 0.014 15.4 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 EER27427.1 - 0.028 13.5 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EER27427.1 - 0.066 13.1 0.1 0.066 13.1 0.1 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family NAD_kinase PF01513.21 EER27428.1 - 2.8e-50 171.2 0.0 5.9e-50 170.1 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EER27428.1 - 0.041 13.5 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Acyltransferase PF01553.21 EER27429.1 - 9.8e-29 99.7 0.0 1.7e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EER27429.1 - 4.6e-13 49.1 0.1 8.6e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus TPR_2 PF07719.17 EER27430.1 - 8e-28 94.3 16.8 0.0073 16.3 0.0 11.6 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_1 PF00515.28 EER27430.1 - 7.6e-21 73.0 19.9 0.01 15.7 0.1 10.5 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 EER27430.1 - 9e-17 61.4 23.8 9.9e-05 22.8 0.2 9.3 9 2 2 11 11 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 EER27430.1 - 3.5e-16 58.0 14.3 0.27 11.5 0.0 11.4 13 0 0 13 13 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 EER27430.1 - 5.3e-14 52.3 12.0 0.00016 21.9 0.0 8.7 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EER27430.1 - 3.3e-11 43.0 30.2 0.019 15.7 0.0 11.8 11 2 1 12 12 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EER27430.1 - 1e-08 35.6 24.8 0.26 12.0 0.1 9.6 10 1 0 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EER27430.1 - 1.1e-08 34.8 12.3 0.27 11.7 0.1 10.1 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_7 PF13176.6 EER27430.1 - 2e-07 30.5 17.4 0.094 12.8 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 EER27430.1 - 3.6e-07 30.4 25.7 1.5 9.6 1.4 12.7 14 0 0 14 14 13 2 Tetratricopeptide repeat TPR_11 PF13414.6 EER27430.1 - 2.9e-05 23.7 26.4 0.11 12.2 0.1 10.3 11 1 2 13 13 13 2 TPR repeat TPR_4 PF07721.14 EER27430.1 - 0.02 15.5 3.2 2.7 8.9 1.3 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat PPR PF01535.20 EER27430.1 - 0.041 14.2 0.2 38 4.8 0.0 4.2 4 0 0 4 4 3 0 PPR repeat LOH1CR12 PF10158.9 EER27430.1 - 0.042 13.9 0.3 0.042 13.9 0.3 3.1 3 1 0 3 3 3 0 Tumour suppressor protein TPR_10 PF13374.6 EER27430.1 - 0.053 13.4 17.3 0.16 11.9 0.0 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TruB_C PF09142.11 EER27430.1 - 0.06 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal TPR_3 PF07720.12 EER27430.1 - 0.064 13.3 14.8 1.5 8.9 0.2 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat EPO_TPO PF00758.18 EER27430.1 - 0.079 13.0 1.7 0.17 11.9 0.4 2.2 2 0 0 2 2 2 0 Erythropoietin/thrombopoietin SGL PF08450.12 EER27431.1 - 1.3e-29 103.5 0.2 4.5e-28 98.5 0.2 2.2 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EER27431.1 - 0.029 14.6 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Arylesterase Str_synth PF03088.16 EER27431.1 - 0.075 13.2 0.0 0.4 10.8 0.0 2.2 2 1 0 2 2 2 0 Strictosidine synthase PBD PF00786.28 EER27432.1 - 0.26 11.7 1.7 0.68 10.3 1.7 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain Pkinase PF00069.25 EER27433.1 - 9.8e-14 51.3 0.0 2e-12 47.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27433.1 - 0.00024 20.5 0.1 0.00069 19.0 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase HNH_2 PF13391.6 EER27434.1 - 8.3e-17 61.1 0.2 2e-16 59.9 0.1 1.7 2 0 0 2 2 2 1 HNH endonuclease Es2 PF09751.9 EER27435.1 - 2.1e-139 466.0 9.5 2.4e-139 465.8 9.5 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 Mid1 PF12929.7 EER27436.1 - 3.7e-155 517.3 0.8 4.3e-155 517.1 0.8 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EER27436.1 - 0.00015 22.3 6.2 0.09 13.4 1.6 2.4 2 0 0 2 2 2 2 Fz domain Kin17_mid PF10357.9 EER27437.1 - 5e-54 181.6 0.6 9.7e-54 180.6 0.6 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EER27437.1 - 0.00016 21.9 3.2 0.00032 21.0 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EER27437.1 - 0.00079 19.6 1.6 0.0017 18.6 1.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EER27437.1 - 0.059 13.7 1.1 0.059 13.7 1.1 2.2 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Presenilin PF01080.17 EER27437.1 - 0.54 9.0 4.3 0.82 8.4 4.3 1.2 1 0 0 1 1 1 0 Presenilin STAC2_u1 PF16664.5 EER27437.1 - 2.3 8.7 8.3 0.6 10.6 4.2 2.1 1 1 1 2 2 2 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Pol_alpha_B_N PF08418.10 EER27437.1 - 4.1 7.3 12.6 8.6 6.2 12.6 1.6 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal CorA PF01544.18 EER27438.1 - 8.1e-40 137.0 0.0 1.8e-39 135.8 0.0 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein TEX29 PF15839.5 EER27439.1 - 0.1 13.2 0.1 0.36 11.5 0.0 1.9 2 0 0 2 2 2 0 Testis-expressed sequence 29 protein zf-rbx1 PF12678.7 EER27440.1 - 5.3e-25 87.5 12.4 7.5e-25 87.0 12.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EER27440.1 - 4.4e-17 61.9 9.7 5.7e-17 61.6 9.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EER27440.1 - 2.3e-06 27.8 14.3 7.7e-05 22.9 14.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER27440.1 - 5.6e-05 22.9 3.3 5.6e-05 22.9 3.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER27440.1 - 0.0024 17.7 11.3 0.038 13.9 11.3 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EER27440.1 - 0.13 12.4 8.5 0.58 10.4 8.7 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EER27440.1 - 0.31 10.9 10.4 0.68 9.8 4.0 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER27440.1 - 0.41 10.7 7.5 1.6 8.8 7.5 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_11 PF17123.5 EER27440.1 - 0.65 9.8 16.1 0.48 10.2 9.1 2.4 1 1 1 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EER27440.1 - 0.98 9.1 14.5 0.16 11.6 4.5 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PNRC PF15365.6 EER27441.1 - 8.7e-09 35.0 9.1 3.3e-08 33.1 7.8 2.9 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif SMI1_KNR4 PF09346.10 EER27442.1 - 1.7e-33 115.8 0.0 3.8e-33 114.7 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Thioredoxin PF00085.20 EER27443.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Zn_clus PF00172.18 EER27444.1 - 8.2e-10 38.6 9.5 1.7e-09 37.7 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_5 PF05631.14 EER27445.1 - 6e-61 206.3 3.4 8.9e-61 205.8 3.4 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EER27445.1 - 4.6e-20 71.8 24.1 5e-20 71.7 20.3 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER27445.1 - 4e-10 39.1 6.2 9.4e-10 37.9 2.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EER27445.1 - 1.5e-05 24.1 0.7 2.6e-05 23.3 0.7 1.6 1 1 0 1 1 1 1 MFS_1 like family DUF21 PF01595.20 EER27445.1 - 0.54 9.9 3.9 0.36 10.5 0.7 2.4 1 1 1 2 2 2 0 Cyclin M transmembrane N-terminal domain Methyltransf_22 PF13383.6 EER27446.1 - 3.2e-23 82.6 0.1 4.5e-23 82.1 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 EER27446.1 - 1.1e-07 32.0 0.0 1.9e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF3316 PF11777.8 EER27446.1 - 0.047 13.8 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) DUF829 PF05705.14 EER27448.1 - 2.7e-52 178.1 0.0 3.3e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) OST-HTH PF12872.7 EER27448.1 - 0.07 13.0 0.1 12 5.8 0.0 3.0 2 1 1 3 3 3 0 OST-HTH/LOTUS domain UFD1 PF03152.14 EER27449.1 - 1.6e-74 249.1 0.0 1.9e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EER27449.1 - 0.0046 16.7 0.0 0.069 12.9 0.0 2.3 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 GYF PF02213.16 EER27450.1 - 5.7e-09 35.5 1.0 1.3e-08 34.4 1.0 1.6 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.13 EER27451.1 - 7.1e-154 512.2 1.3 9e-154 511.9 1.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EER27451.1 - 7.4e-21 74.1 0.4 2.7e-20 72.3 0.2 2.1 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EER27451.1 - 3.6e-08 33.9 0.1 4.9e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EER27451.1 - 1e-07 31.8 0.3 9.2e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EER27451.1 - 3.7e-06 26.5 0.6 6.5e-06 25.7 0.6 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EER27451.1 - 4.7e-06 27.1 0.1 1.3e-05 25.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EER27451.1 - 0.0055 16.1 0.7 0.076 12.4 0.3 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EER27451.1 - 0.0068 16.4 0.0 0.65 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EER27451.1 - 0.013 15.3 0.0 5.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.6 EER27451.1 - 0.032 14.4 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EER27451.1 - 0.041 13.5 0.1 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EER27451.1 - 0.044 14.1 1.6 0.9 9.9 1.6 2.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EER27451.1 - 0.066 13.0 0.6 0.23 11.2 0.6 1.9 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EER27451.1 - 0.12 11.9 0.2 0.47 9.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DNA_pol3_delta PF06144.13 EER27451.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Parvo_NS1 PF01057.17 EER27451.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF4041 PF13250.6 EER27452.1 - 0.13 12.1 3.7 13 5.7 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4041) Unstab_antitox PF09720.10 EER27452.1 - 0.72 9.9 5.6 1.9 8.6 0.1 3.9 4 0 0 4 4 4 0 Putative addiction module component NPV_P10 PF05531.12 EER27452.1 - 1.4 9.4 17.9 1.8 9.1 0.1 5.5 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein HU-CCDC81_bac_2 PF18175.1 EER27452.1 - 2.2 8.2 3.9 1.5 8.8 0.3 2.7 3 0 0 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Baculo_PEP_C PF04513.12 EER27452.1 - 6.5 6.8 22.8 0.91 9.6 0.6 4.2 2 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FSH1 PF03959.13 EER27453.1 - 3.3e-25 89.0 0.0 4.2e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EER27453.1 - 0.037 13.8 0.1 0.17 11.6 0.0 2.1 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1870 PF08965.10 EER27454.1 - 0.038 14.0 0.1 0.055 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) ORC6 PF05460.13 EER27455.1 - 0.0016 17.8 1.2 0.0017 17.7 1.2 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Auxin_repressed PF05564.12 EER27455.1 - 0.033 14.9 1.6 0.046 14.4 1.5 1.3 1 1 0 1 1 1 0 Dormancy/auxin associated protein HTH_Mga PF08280.11 EER27455.1 - 0.09 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Myb_DNA-binding PF00249.31 EER27456.1 - 0.0033 17.6 0.0 0.0046 17.1 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain ORC6 PF05460.13 EER27456.1 - 0.43 9.8 3.6 0.48 9.6 3.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PGA_cap PF09587.10 EER27459.1 - 0.19 11.2 1.0 0.22 10.9 1.0 1.4 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap ORC6 PF05460.13 EER27459.1 - 0.2 10.9 8.6 0.23 10.7 8.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Spore_coat_CotO PF14153.6 EER27459.1 - 2.9 7.8 8.2 3.7 7.5 7.4 1.5 1 1 0 1 1 1 0 Spore coat protein CotO Abp2 PF09441.10 EER27460.1 - 9.5e-83 276.4 0.0 1.5e-82 275.7 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TENA_THI-4 PF03070.16 EER27460.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family DUF3464 PF11947.8 EER27461.1 - 0.089 12.5 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 WW PF00397.26 EER27462.1 - 1.3e-06 28.4 1.0 3.3e-06 27.1 1.0 1.8 1 0 0 1 1 1 1 WW domain Brix PF04427.18 EER27463.1 - 2.3e-30 106.2 0.0 3.3e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Brix domain F-box-like PF12937.7 EER27464.1 - 0.0022 17.9 0.1 0.059 13.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like Ras PF00071.22 EER27465.1 - 5.1e-63 211.5 0.2 6e-63 211.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER27465.1 - 2.9e-35 121.1 0.2 4e-35 120.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER27465.1 - 6.8e-13 48.4 0.1 9.1e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EER27465.1 - 1.1e-07 31.9 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER27465.1 - 9.6e-05 22.3 0.1 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EER27465.1 - 0.00028 20.5 0.1 0.0012 18.4 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EER27465.1 - 0.00057 19.3 0.1 0.00092 18.6 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EER27465.1 - 0.0018 18.5 0.1 0.015 15.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EER27465.1 - 0.014 15.5 0.2 0.04 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EER27465.1 - 0.014 15.8 0.1 0.022 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EER27465.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EER27465.1 - 0.019 15.5 0.1 0.027 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EER27465.1 - 0.022 14.5 0.1 0.058 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EER27465.1 - 0.037 13.4 0.0 0.17 11.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 EER27465.1 - 0.047 13.5 0.7 0.07 12.9 0.7 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system SpoIIID PF12116.8 EER27465.1 - 0.079 13.1 0.1 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_7 PF12775.7 EER27465.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 EER27465.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.14 EER27465.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.24 EER27466.1 - 1.6e-09 37.5 0.3 1.6e-09 37.5 0.3 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain TarH PF02203.15 EER27466.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue AAA_2 PF07724.14 EER27467.1 - 2.6e-37 128.5 0.0 2.3e-36 125.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EER27467.1 - 1.4e-14 54.7 0.0 3e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EER27467.1 - 2.2e-09 37.2 0.0 5.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EER27467.1 - 1.2e-06 28.6 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EER27467.1 - 0.00015 21.2 0.1 0.011 15.1 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EER27467.1 - 0.00096 18.9 0.0 0.077 12.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 EER27467.1 - 0.0032 17.9 1.4 0.016 15.6 0.1 2.5 2 1 1 3 3 3 1 AAA ATPase domain MCM PF00493.23 EER27467.1 - 0.0032 16.6 0.1 0.0075 15.4 0.1 1.6 1 0 0 1 1 1 1 MCM P-loop domain IstB_IS21 PF01695.17 EER27467.1 - 0.0033 17.2 0.0 0.0067 16.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EER27467.1 - 0.005 16.6 0.2 0.11 12.3 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EER27467.1 - 0.0057 16.4 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EER27467.1 - 0.006 16.9 0.2 0.038 14.3 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EER27467.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EER27467.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EER27467.1 - 0.085 13.4 0.2 0.24 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.11 EER27467.1 - 0.089 12.7 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EER27467.1 - 0.093 12.3 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EER27467.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain FAD_binding_4 PF01565.23 EER27468.1 - 1.9e-19 69.8 0.9 3.5e-19 68.9 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EER27468.1 - 7e-11 42.0 0.1 1.4e-10 41.1 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ATP-synt_ab PF00006.25 EER27469.1 - 1.1e-61 208.2 0.0 1.9e-61 207.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EER27469.1 - 1.5e-22 79.9 2.8 2.7e-22 79.0 1.5 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 EER27469.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 EER27469.1 - 0.018 15.4 0.0 0.6 10.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EER27469.1 - 0.023 14.6 0.0 0.077 12.9 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T3SS_ATPase_C PF18269.1 EER27469.1 - 0.037 13.9 0.9 0.17 11.8 0.9 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NB-ARC PF00931.22 EER27469.1 - 0.044 13.0 0.9 0.096 11.9 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 EER27469.1 - 0.045 13.1 0.2 0.085 12.2 0.2 1.5 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EER27469.1 - 0.055 13.4 0.2 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 EER27469.1 - 0.07 13.5 1.8 0.49 10.7 0.2 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EER27469.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EER27469.1 - 0.084 13.3 0.1 0.34 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain EKR PF10371.9 EER27469.1 - 0.16 11.8 0.4 2.4 8.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function Alpha-amylase_C PF02806.18 EER27470.1 - 4.9e-28 97.5 0.1 1.4e-27 96.0 0.1 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EER27470.1 - 7e-20 71.2 0.0 1.8e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EER27470.1 - 2e-16 60.5 0.0 2.7e-12 46.9 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EER27470.1 - 0.029 13.5 0.3 0.19 10.8 0.1 2.1 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain COX4 PF02936.14 EER27471.1 - 3.6e-46 156.6 0.8 4.4e-46 156.3 0.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 EER27471.1 - 0.036 14.5 2.2 0.036 14.5 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1104 PF06518.11 EER27471.1 - 0.2 12.1 0.8 0.3 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Cofilin_ADF PF00241.20 EER27472.1 - 7e-35 119.5 0.0 7.9e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.24 EER27473.1 - 6.8e-86 288.8 11.9 1.5e-85 287.7 11.9 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Spaetzle PF16077.5 EER27474.1 - 0.096 13.2 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 Spaetzle ATP-synt_Eps PF04627.13 EER27475.1 - 3e-22 78.3 1.6 4.2e-22 77.9 1.6 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.13 EER27476.1 - 2.3e-63 212.7 0.0 4.2e-63 211.8 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase NAGLU_N PF12971.7 EER27476.1 - 0.018 14.8 0.1 0.054 13.3 0.1 1.8 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain SpecificRecomb PF10136.9 EER27476.1 - 0.03 12.6 0.3 0.04 12.2 0.3 1.1 1 0 0 1 1 1 0 Site-specific recombinase ORC5_C PF14630.6 EER27477.1 - 9.5e-77 258.3 0.0 1.4e-76 257.7 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EER27477.1 - 1.3e-21 77.7 0.0 2.9e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 EER27477.1 - 0.00078 19.4 0.0 0.0047 16.9 0.0 2.3 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EER27477.1 - 0.0056 16.9 0.0 0.023 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EER27477.1 - 0.0058 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EER27477.1 - 0.015 15.8 0.0 0.03 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 EER27477.1 - 0.019 14.2 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF815 PF05673.13 EER27477.1 - 0.035 13.3 0.0 0.25 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EER27477.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EER27477.1 - 0.044 13.0 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EER27477.1 - 0.053 13.9 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EER27477.1 - 0.084 13.3 0.0 0.25 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EER27477.1 - 0.12 12.9 0.0 0.31 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EER27477.1 - 0.15 12.6 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PUF PF00806.19 EER27478.1 - 1e-57 188.7 5.1 1.6e-07 30.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF3340 PF11818.8 EER27478.1 - 0.0055 16.9 0.2 0.016 15.4 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of tail specific protease (DUF3340) RNA_pol_Rpb2_6 PF00562.28 EER27479.1 - 6.2e-123 410.7 0.0 1e-122 410.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EER27479.1 - 2.3e-54 184.0 0.4 3.3e-54 183.5 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EER27479.1 - 1.4e-31 108.8 0.8 5.8e-31 106.7 0.3 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EER27479.1 - 1.5e-29 103.0 1.6 3.6e-29 101.7 1.3 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EER27479.1 - 1.3e-25 89.5 0.4 3.4e-25 88.1 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EER27479.1 - 1.8e-19 69.6 0.0 4e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EER27479.1 - 2.8e-11 43.8 1.2 7.8e-11 42.4 1.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Glycos_transf_1 PF00534.20 EER27481.1 - 7.6e-21 74.4 0.0 1.9e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EER27481.1 - 2.9e-13 50.4 0.0 5.6e-13 49.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EER27481.1 - 0.00018 21.9 0.0 0.00044 20.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 E1-E2_ATPase PF00122.20 EER27482.1 - 4.6e-48 163.1 6.6 4.6e-48 163.1 6.6 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EER27482.1 - 2e-17 64.2 0.0 6.2e-17 62.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EER27482.1 - 5.4e-11 42.0 0.0 1.2e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EER27482.1 - 0.0024 17.7 0.1 0.005 16.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EER27482.1 - 0.024 14.7 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) O-antigen_lig PF13425.6 EER27482.1 - 0.12 11.1 6.1 0.38 9.5 6.1 1.7 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CTD_bind PF04818.13 EER27483.1 - 5.6e-09 36.7 0.0 1.1e-08 35.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EER27483.1 - 2.4e-06 27.3 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 EER27483.1 - 0.72 9.8 22.7 1.1 9.1 22.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Citrate_synt PF00285.21 EER27484.1 - 1.8e-100 336.5 0.0 2.3e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Mito_carr PF00153.27 EER27485.1 - 5e-26 90.4 4.7 2e-12 46.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_M16 PF00675.20 EER27486.1 - 8.1e-19 68.1 0.0 1.6e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EER27486.1 - 6.3e-12 45.9 0.0 1.3e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 EER27487.1 - 1.3e-37 130.0 0.0 7.1e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EER27487.1 - 5.2e-20 71.3 3.3 2.9e-15 56.1 0.2 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EER27487.1 - 2e-09 37.3 0.0 0.00035 20.4 0.1 2.8 2 0 0 2 2 2 2 TFIIE alpha subunit MarR_2 PF12802.7 EER27487.1 - 0.015 15.2 0.0 29 4.6 0.0 3.9 3 1 1 4 4 4 0 MarR family Pga1 PF10333.9 EER27488.1 - 9.3e-07 28.9 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.25 EER27489.1 - 1.2e-66 224.7 0.0 1.6e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EER27489.1 - 1.3e-49 167.5 0.0 2.9e-49 166.4 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EER27489.1 - 0.0044 16.7 0.0 0.0094 15.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.7 EER27490.1 - 3.2e-39 133.1 0.0 4.5e-15 55.5 0.0 3.9 4 0 0 4 4 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EER27490.1 - 8.9e-10 37.4 1.6 0.00074 18.9 0.0 5.1 6 0 0 6 6 6 2 EF hand EF-hand_7 PF13499.6 EER27490.1 - 8.1e-09 35.8 0.0 8.1e-05 23.0 0.3 4.0 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_8 PF13833.6 EER27490.1 - 3e-05 23.8 0.2 0.053 13.4 0.1 4.1 3 1 1 4 4 4 1 EF-hand domain pair UBA PF00627.31 EER27490.1 - 8.8e-05 22.3 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.6 EER27490.1 - 0.00026 20.6 3.7 1.7 8.8 0.0 5.6 5 0 0 5 5 5 1 EF-hand domain DUF812 PF05667.11 EER27490.1 - 0.0021 17.0 17.0 0.0051 15.8 16.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Spc7 PF08317.11 EER27490.1 - 0.0036 16.2 32.9 0.025 13.5 18.0 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein GAS PF13851.6 EER27490.1 - 0.016 14.5 30.9 0.15 11.4 23.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EF-hand_5 PF13202.6 EER27490.1 - 0.078 12.5 0.1 0.33 10.5 0.1 2.1 1 0 0 1 1 1 0 EF hand ATG16 PF08614.11 EER27490.1 - 0.1 12.8 34.2 0.23 11.7 21.5 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 EER27490.1 - 0.27 11.5 32.7 7.5 6.8 3.6 3.4 1 1 2 3 3 3 0 Tho complex subunit 7 HOOK PF05622.12 EER27490.1 - 1.1 7.4 26.4 1.7 6.7 26.4 1.2 1 0 0 1 1 1 0 HOOK protein MAD PF05557.13 EER27490.1 - 1.8 6.8 26.1 2.8 6.2 26.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF1664 PF07889.12 EER27490.1 - 2.1 8.4 17.8 0.51 10.4 5.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) LPP PF04728.13 EER27490.1 - 2.3 8.7 15.3 0.3 11.5 1.0 3.8 3 1 0 3 3 3 0 Lipoprotein leucine-zipper PRKG1_interact PF15898.5 EER27490.1 - 3.6 8.5 27.8 1.2 10.0 6.7 3.6 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain TPR_MLP1_2 PF07926.12 EER27490.1 - 9.3 6.3 35.2 1.1 9.3 17.0 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 EER27490.1 - 9.7 6.2 29.2 4 7.4 9.4 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MARVEL PF01284.23 EER27491.1 - 1e-18 67.7 14.5 1.3e-18 67.4 14.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.20 EER27492.1 - 1.6e-152 507.5 0.0 1.8e-152 507.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EER27492.1 - 9.5e-12 44.9 0.2 1.8e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EER27492.1 - 5.4e-09 35.7 0.1 1.1e-08 34.6 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EER27492.1 - 4.9e-08 32.3 0.3 8.8e-08 31.5 0.3 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EER27492.1 - 0.0005 19.5 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EER27492.1 - 0.026 13.1 0.1 0.033 12.7 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase Asparaginase_C PF17763.1 EER27492.1 - 0.047 13.9 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 EER27492.1 - 0.066 11.9 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 EER27492.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein AMP-binding PF00501.28 EER27493.1 - 7.4e-83 278.5 0.0 8.8e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.10 EER27494.1 - 2.3e-28 98.8 0.0 3.1e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) SOP4 PF17081.5 EER27494.1 - 0.068 12.7 0.0 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 Suppressor of PMA 1-7 protein Sugarporin_N PF11471.8 EER27494.1 - 0.19 11.7 0.4 0.6 10.1 0.4 1.8 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension WW PF00397.26 EER27495.1 - 2.1e-07 30.9 4.5 3.9e-07 30.0 4.5 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 EER27495.1 - 0.0012 19.0 22.2 0.0012 19.0 22.2 2.3 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Ank_2 PF12796.7 EER27496.1 - 3.4e-112 367.2 10.8 2.6e-15 56.8 0.0 6.6 1 1 7 8 8 8 8 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EER27496.1 - 1.3e-73 234.1 0.0 6.5e-06 26.1 0.0 11.8 11 0 0 11 11 11 10 Ankyrin repeat Ank PF00023.30 EER27496.1 - 2.8e-72 236.2 0.0 5.2e-06 26.7 0.0 12.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.6 EER27496.1 - 8.6e-68 223.9 0.0 1.8e-11 44.3 0.0 8.2 2 1 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EER27496.1 - 2.4e-50 167.9 2.4 1e-08 35.3 0.1 9.3 2 2 7 9 9 9 9 Ankyrin repeats (many copies) SIR2_2 PF13289.6 EER27496.1 - 4.2e-16 59.4 0.0 1.2e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 SIR2-like domain Shigella_OspC PF06128.11 EER27496.1 - 4.3e-06 26.7 4.3 6.9 6.3 0.0 5.8 2 2 3 6 6 6 2 Shigella flexneri OspC protein INTS5_C PF14838.6 EER27496.1 - 1.7e-05 23.7 1.1 0.12 11.0 0.1 3.3 1 1 2 4 4 4 3 Integrator complex subunit 5 C-terminus Apolipoprotein PF01442.18 EER27496.1 - 2.2e-05 24.4 2.2 0.034 14.0 0.1 2.6 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain HTH_22 PF13309.6 EER27496.1 - 0.00047 20.2 4.4 40 4.4 0.0 6.7 7 1 0 7 7 6 0 HTH domain CarD_CdnL_TRCF PF02559.16 EER27496.1 - 0.0016 19.1 6.1 12 6.7 0.2 5.4 4 2 1 5 5 5 0 CarD-like/TRCF domain ScdA_N PF04405.14 EER27496.1 - 0.0021 17.7 0.0 6.3 6.6 0.0 4.5 5 0 0 5 5 5 1 Domain of Unknown function (DUF542) Gp-FAR-1 PF05823.12 EER27496.1 - 0.019 15.3 1.3 5.6 7.3 0.2 3.2 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Spore_SspJ PF09575.10 EER27496.1 - 0.028 14.8 11.9 1.4 9.3 0.2 6.8 6 2 1 7 7 7 0 Small spore protein J (Spore_SspJ) BLACT_WH PF17778.1 EER27496.1 - 0.03 14.3 3.1 0.76 9.8 0.0 4.1 4 0 0 4 4 4 0 Beta-lactamase associated winged helix domain SRI PF08236.11 EER27496.1 - 0.052 13.7 2.0 7.6 6.8 0.3 3.9 2 1 1 3 3 3 0 SRI (Set2 Rpb1 interacting) domain FATC PF02260.20 EER27496.1 - 0.063 13.1 0.2 2e+02 1.9 0.0 5.1 6 0 0 6 6 6 0 FATC domain FliT PF05400.13 EER27496.1 - 0.074 13.9 13.4 6.9 7.6 0.4 5.8 3 1 4 7 7 7 0 Flagellar protein FliT RraB PF06877.11 EER27496.1 - 0.16 12.7 1.1 1.4e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 Regulator of ribonuclease activity B Peptidase_M60 PF13402.6 EER27496.1 - 0.5 9.8 4.6 85 2.5 0.0 5.1 3 1 3 6 6 6 0 Peptidase M60, enhancin and enhancin-like V-ATPase_G PF03179.15 EER27496.1 - 2.1 8.9 8.4 53 4.4 0.3 4.8 3 2 3 6 6 5 0 Vacuolar (H+)-ATPase G subunit WD40 PF00400.32 EER27497.1 - 7.9e-07 29.7 13.1 0.058 14.3 0.1 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 EER27497.1 - 0.013 14.2 0.1 0.046 12.4 0.1 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EER27497.1 - 0.022 15.0 0.1 1.2 9.5 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Mito_carr PF00153.27 EER27498.1 - 8.3e-54 179.5 1.3 4.1e-17 61.9 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.16 EER27498.1 - 0.013 15.4 0.5 0.034 14.1 0.1 2.0 2 0 0 2 2 2 0 UcrQ family ATP-synt_I PF03899.15 EER27498.1 - 0.03 14.7 7.2 0.34 11.3 0.0 3.5 3 1 1 4 4 4 0 ATP synthase I chain Ras PF00071.22 EER27499.1 - 8.1e-66 220.6 0.5 9.4e-66 220.4 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER27499.1 - 6.9e-36 123.1 0.1 1.2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER27499.1 - 1.8e-16 60.1 0.1 2.1e-16 59.8 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EER27499.1 - 1.5e-05 25.0 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EER27499.1 - 2.6e-05 24.3 0.0 0.0001 22.3 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER27499.1 - 0.00011 21.8 0.3 0.00031 20.3 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EER27499.1 - 0.00022 20.7 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 EER27499.1 - 0.00059 20.3 0.1 0.23 11.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EER27499.1 - 0.00079 18.9 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EER27499.1 - 0.0036 16.8 0.0 0.022 14.3 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EER27499.1 - 0.0083 16.5 0.0 0.012 16.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EER27499.1 - 0.033 13.5 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_22 PF13401.6 EER27499.1 - 0.038 14.3 0.0 0.067 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EER27499.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EER27499.1 - 0.063 12.7 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 EER27499.1 - 0.064 13.8 0.1 0.15 12.6 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EER27499.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EER27499.1 - 0.075 12.6 0.1 2.2 7.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EER27499.1 - 0.086 12.6 0.1 0.67 9.7 0.1 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EER27499.1 - 0.092 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ERAP1_C PF11838.8 EER27500.1 - 6.1e-89 298.7 0.1 1e-88 297.9 0.1 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EER27500.1 - 9.7e-82 273.7 2.9 1.5e-81 273.1 2.9 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EER27500.1 - 1.9e-40 139.0 0.3 1.3e-39 136.4 0.1 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Ssl1 PF04056.14 EER27501.1 - 4.6e-75 251.7 0.0 6e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EER27501.1 - 1.3e-19 70.1 6.9 1.3e-19 70.1 6.9 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EER27501.1 - 1e-14 55.0 0.0 2.2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.7 EER27501.1 - 0.11 12.5 18.3 0.44 10.6 5.0 3.0 2 1 0 2 2 2 0 Double zinc ribbon YL1 PF05764.13 EER27501.1 - 1.5 8.9 6.8 2.1 8.4 6.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_S9 PF00326.21 EER27502.1 - 0.00025 20.6 0.2 0.00049 19.6 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EER27502.1 - 0.0013 18.4 0.2 0.0029 17.3 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EER27502.1 - 0.0025 17.5 0.2 0.0054 16.4 0.2 1.5 1 0 0 1 1 1 1 Putative esterase Alpha-amyl_C PF09071.10 EER27502.1 - 0.089 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Alpha-amylase, C terminal PUF PF00806.19 EER27503.1 - 5.9e-35 117.0 1.1 7.2e-06 25.4 0.0 9.4 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat RraB PF06877.11 EER27503.1 - 0.045 14.5 0.0 0.25 12.1 0.0 2.2 2 0 0 2 2 2 0 Regulator of ribonuclease activity B CPL PF08144.11 EER27503.1 - 0.19 12.1 0.0 10 6.5 0.0 2.8 2 0 0 2 2 2 0 CPL (NUC119) domain Inhibitor_I36 PF03995.13 EER27503.1 - 1.7 8.6 5.2 12 5.9 5.2 2.2 1 1 0 1 1 1 0 Peptidase inhibitor family I36 DUF5572 PF17733.1 EER27504.1 - 7.4e-24 83.3 0.2 7.4e-24 83.3 0.2 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5572) SPATA3 PF15662.5 EER27504.1 - 8.5 7.0 14.0 2 9.0 10.4 1.8 2 0 0 2 2 2 0 Spermatogenesis-associated protein 3 family TPT PF03151.16 EER27505.1 - 2.1e-58 198.0 11.5 2.7e-58 197.6 11.5 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EER27505.1 - 9.2e-07 29.1 30.2 0.002 18.3 11.7 3.2 2 1 0 2 2 2 2 EamA-like transporter family PSII PF00421.19 EER27505.1 - 8.5e-05 21.4 0.1 0.00016 20.5 0.1 1.4 1 0 0 1 1 1 1 Photosystem II protein UAA PF08449.11 EER27505.1 - 0.0087 15.3 11.8 0.24 10.6 6.0 2.4 2 1 0 2 2 2 2 UAA transporter family Multi_Drug_Res PF00893.19 EER27505.1 - 5.6 7.7 10.7 0.69 10.6 1.0 3.5 2 1 2 4 4 4 0 Small Multidrug Resistance protein RVT_2 PF07727.14 EER27506.1 - 6.1e-51 173.4 0.0 9.3e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EER27506.1 - 1.7e-14 54.0 0.0 8.9e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EER27506.1 - 4.2e-06 26.5 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 EER27506.1 - 0.001 19.0 1.7 0.0022 18.0 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 EER27506.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type rve_3 PF13683.6 EER27506.1 - 0.082 12.7 0.1 2.8 7.8 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain Neugrin PF06413.11 EER27506.1 - 0.22 11.5 7.2 0.49 10.4 5.9 2.3 2 0 0 2 2 2 0 Neugrin Molybdopterin PF00384.22 EER27507.1 - 1.5e-73 248.3 0.0 1.7e-36 126.1 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 EER27507.1 - 5.5e-19 68.6 0.0 1.2e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EER27507.1 - 2.4e-17 62.2 0.2 2.4e-17 62.2 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4_19 PF06902.11 EER27507.1 - 0.084 13.0 0.1 22 5.2 0.0 2.5 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Fer4 PF00037.27 EER27507.1 - 0.11 12.3 1.1 3 7.8 0.3 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.7 EER27507.1 - 0.35 11.0 2.4 0.46 10.7 1.0 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain XRCC4 PF06632.12 EER27508.1 - 6.7e-06 25.2 22.9 0.00037 19.5 22.7 2.8 2 1 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 FUSC PF04632.12 EER27508.1 - 0.18 10.3 2.1 0.12 10.9 0.3 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family ACTH_assoc PF16102.5 EER27509.1 - 0.031 15.0 0.1 0.031 15.0 0.1 3.2 3 0 0 3 3 3 0 ACTH-associated domain ADP_PFK_GK PF04587.15 EER27511.1 - 0.037 12.6 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region ER_lumen_recept PF00810.18 EER27512.1 - 2.1e-55 187.6 9.3 3.1e-55 187.0 9.3 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EER27512.1 - 0.087 12.6 14.1 1.1 9.1 0.1 3.7 4 0 0 4 4 4 0 PQ loop repeat DUF382 PF04037.13 EER27514.1 - 2.1e-60 202.4 2.0 6.3e-60 200.9 2.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 EER27514.1 - 1.8e-20 72.5 4.9 4.5e-20 71.2 4.9 1.7 1 0 0 1 1 1 1 PSP MRP-S33 PF08293.11 EER27515.1 - 1.3e-29 102.3 0.0 1.7e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF866 PF05907.13 EER27515.1 - 0.0003 20.8 0.0 0.00036 20.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ribonuclease_3 PF00636.26 EER27516.1 - 1.7e-15 57.5 0.1 2.2e-14 53.9 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EER27516.1 - 7.5e-11 42.3 0.0 1.8e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 EER27516.1 - 0.051 14.3 0.0 0.13 13.0 0.0 1.8 1 0 0 1 1 1 0 Double-stranded RNA binding motif Sulphotransf PF09037.10 EER27516.1 - 0.092 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Stf0 sulphotransferase GPI-anchored PF10342.9 EER27517.1 - 9.3e-18 64.8 0.1 1.2e-17 64.5 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CDC45 PF02724.14 EER27517.1 - 0.76 8.0 8.3 0.82 7.9 8.3 1.0 1 0 0 1 1 1 0 CDC45-like protein ECH_1 PF00378.20 EER27518.1 - 3.2e-41 141.3 0.0 4.3e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER27518.1 - 4.3e-28 98.8 0.0 5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase RTA1 PF04479.13 EER27519.1 - 1.6e-35 122.6 2.9 2.2e-35 122.2 2.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_1 PF00561.20 EER27521.1 - 1.1e-24 87.5 0.0 3.2e-19 69.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER27521.1 - 5.3e-14 53.4 0.0 9.7e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER27521.1 - 6.3e-12 45.3 0.0 9.8e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EER27521.1 - 5.6e-06 26.2 0.2 0.00079 19.2 0.2 2.2 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EER27521.1 - 1.6e-05 25.1 0.0 2.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EER27521.1 - 0.00054 19.7 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.16 EER27521.1 - 0.0014 18.2 0.0 0.0075 15.8 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Chlorophyllase2 PF12740.7 EER27521.1 - 0.0038 16.2 0.0 0.06 12.2 0.0 2.2 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EER27521.1 - 0.0038 16.3 0.0 0.0092 15.0 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase Palm_thioest PF02089.15 EER27521.1 - 0.0057 16.5 0.0 0.0081 16.0 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase UPF0227 PF05728.12 EER27521.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 EER27521.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EER27521.1 - 0.033 14.0 0.0 2.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 EER27521.1 - 0.062 13.2 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.14 EER27521.1 - 0.098 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 EER27521.1 - 0.17 11.7 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 EER27521.1 - 0.19 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Ribosomal_S3Ae PF01015.18 EER27522.1 - 1.7e-84 282.5 4.7 2e-84 282.2 4.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EER27522.1 - 0.072 13.6 0.2 0.21 12.1 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor SUI1 GTP_CH_N PF12471.8 EER27523.1 - 9.9e-92 306.0 0.0 1.6e-91 305.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EER27523.1 - 4.4e-15 55.7 0.0 7.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.21 EER27523.1 - 0.057 13.1 0.0 64 3.3 0.0 3.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family UPRTase PF14681.6 EER27524.1 - 1.7e-78 262.8 0.0 2.1e-78 262.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EER27524.1 - 0.00052 19.6 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 EER27524.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.13 EER27525.1 - 5.2e-80 269.0 5.6 7.7e-80 268.4 5.6 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.22 EER27526.1 - 2.8e-47 160.3 0.1 3.2e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER27526.1 - 1.4e-16 60.8 0.0 1.9e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER27526.1 - 1.2e-06 28.1 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EER27526.1 - 0.00011 22.3 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER27526.1 - 0.00012 21.7 0.0 0.0022 17.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EER27526.1 - 0.00092 19.2 0.0 0.29 11.0 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EER27526.1 - 0.0047 16.4 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EER27526.1 - 0.1 12.2 0.1 0.17 11.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B tRNA-synt_2b PF00587.25 EER27527.1 - 8.3e-37 126.9 0.0 1.5e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EER27527.1 - 8.2e-19 67.8 9.0 8.2e-19 67.8 9.0 2.5 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain ICL PF00463.21 EER27527.1 - 0.0056 15.2 1.9 0.0098 14.4 1.9 1.3 1 0 0 1 1 1 1 Isocitrate lyase family 2-Hacid_dh_C PF02826.19 EER27528.1 - 1.2e-52 177.9 0.0 2e-52 177.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER27528.1 - 3.6e-38 130.2 0.0 5.1e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EER27528.1 - 5e-06 26.8 1.5 8.7e-06 26.0 0.4 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 EER27528.1 - 2.3e-05 24.0 0.1 5.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.21 EER27528.1 - 0.00076 19.6 0.1 0.002 18.2 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 EER27528.1 - 0.0047 16.5 0.3 0.044 13.3 0.1 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EER27528.1 - 0.021 14.7 2.0 2.3 8.1 0.5 3.1 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 EER27528.1 - 0.041 14.4 0.1 0.11 13.1 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain DUF1780 PF08682.10 EER27528.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) RPN5_C PF18098.1 EER27528.1 - 7.2 6.8 7.8 26 5.0 0.8 3.3 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain Pkinase PF00069.25 EER27529.1 - 2.8e-56 190.8 0.0 1.2e-54 185.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27529.1 - 2.4e-19 69.6 0.0 2.6e-17 63.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase P5-ATPase PF12409.8 EER27530.1 - 1.9e-37 128.2 0.1 3.5e-37 127.3 0.1 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EER27530.1 - 4.8e-31 107.7 0.9 2.2e-30 105.5 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EER27530.1 - 2e-10 41.3 0.0 6.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EER27530.1 - 2.8e-07 30.5 4.8 2.8e-07 30.5 4.8 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EER27530.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EER27530.1 - 0.0015 18.2 0.0 0.0031 17.1 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EER27530.1 - 0.05 13.3 0.0 10 5.8 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase NAP PF00956.18 EER27531.1 - 6.2e-100 333.8 11.8 1e-99 333.1 11.8 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) BUD22 PF09073.10 EER27531.1 - 1.1 8.5 25.2 2.6 7.3 17.0 2.1 2 0 0 2 2 2 0 BUD22 Striatin PF08232.12 EER27531.1 - 6.3 7.4 12.9 0.044 14.4 2.3 2.4 2 1 0 2 2 2 0 Striatin family RNA_pol_3_Rpc31 PF11705.8 EER27531.1 - 9.5 6.4 32.8 31 4.7 22.5 3.1 2 1 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Myosin_head PF00063.21 EER27532.1 - 1.1e-262 873.3 0.6 1.5e-262 872.8 0.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EER27532.1 - 4.2e-26 91.2 2.9 4.2e-26 91.2 2.9 2.9 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 EER27532.1 - 1e-11 43.5 29.3 7e-05 22.3 1.4 6.6 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_16 PF13191.6 EER27532.1 - 0.00027 21.4 0.3 0.0011 19.4 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain Myosin_N PF02736.19 EER27532.1 - 0.001 18.8 1.8 0.0023 17.7 1.8 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain GAS PF13851.6 EER27532.1 - 0.0032 16.9 14.7 0.0032 16.9 14.7 2.6 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 EER27532.1 - 0.011 14.7 20.8 0.019 13.9 20.8 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like T2SSE PF00437.20 EER27532.1 - 0.013 14.6 0.0 0.033 13.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Baculo_PEP_C PF04513.12 EER27532.1 - 0.021 14.9 6.6 0.11 12.6 6.6 2.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_22 PF13401.6 EER27532.1 - 0.024 14.9 3.2 0.029 14.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain Sec34 PF04136.15 EER27532.1 - 0.071 13.0 4.6 0.11 12.3 3.3 2.1 1 1 0 1 1 1 0 Sec34-like family TMP_2 PF06791.13 EER27532.1 - 0.079 12.6 1.5 0.19 11.4 1.5 1.5 1 0 0 1 1 1 0 Prophage tail length tape measure protein Phage_GP20 PF06810.11 EER27532.1 - 0.084 12.7 15.8 0.16 11.8 10.0 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 RNA_helicase PF00910.22 EER27532.1 - 0.13 12.6 0.0 0.87 10.0 0.0 2.5 2 0 0 2 2 1 0 RNA helicase zf-C4H2 PF10146.9 EER27532.1 - 0.14 12.4 4.1 0.56 10.5 4.1 2.1 1 0 0 1 1 1 0 Zinc finger-containing protein DUF484 PF04340.12 EER27532.1 - 0.17 11.5 7.0 0.42 10.3 7.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF484 Noelin-1 PF12308.8 EER27532.1 - 0.31 11.1 2.0 1.4 8.9 2.0 2.2 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF812 PF05667.11 EER27532.1 - 0.37 9.6 18.9 0.63 8.8 18.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TSNAXIP1_N PF15739.5 EER27532.1 - 0.72 10.2 10.2 0.31 11.4 3.3 3.2 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus FlaC_arch PF05377.11 EER27532.1 - 0.81 10.1 7.3 2.5 8.6 0.2 4.2 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) FUSC PF04632.12 EER27532.1 - 1.2 7.6 7.9 2.1 6.8 7.9 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 EER27532.1 - 1.3 8.8 27.9 1.4 8.7 9.8 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Cortex-I_coil PF09304.10 EER27532.1 - 3.2 8.0 18.5 0.038 14.2 6.3 2.8 1 1 1 2 2 1 0 Cortexillin I, coiled coil Macoilin PF09726.9 EER27532.1 - 3.3 6.1 19.3 5.2 5.5 19.3 1.2 1 0 0 1 1 1 0 Macoilin family DUF3450 PF11932.8 EER27532.1 - 4.3 6.6 22.4 0.79 9.0 14.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 EER27532.1 - 4.7 7.4 29.3 8.2 6.6 9.2 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DegQ PF08181.11 EER27532.1 - 5.4 7.2 7.2 0.56 10.3 0.6 2.7 2 0 0 2 2 2 0 DegQ (SacQ) family Ham1p_like PF01725.16 EER27533.1 - 3.6e-58 196.6 0.0 4e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.6 EER27534.1 - 1.7e-25 90.1 0.1 3.4e-25 89.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EER27534.1 - 1.6e-08 35.1 0.0 4.4e-08 33.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EER27534.1 - 0.00011 22.6 0.0 0.00048 20.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EER27534.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain ADK PF00406.22 EER27534.1 - 0.0019 18.3 0.1 0.0094 16.1 0.1 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.6 EER27534.1 - 0.0036 17.5 0.0 0.011 15.9 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EER27534.1 - 0.0048 17.2 0.0 0.01 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EER27534.1 - 0.0081 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EER27534.1 - 0.012 15.5 0.2 0.031 14.2 0.1 1.7 2 0 0 2 2 2 0 NTPase Death PF00531.22 EER27534.1 - 0.013 15.6 0.2 6.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Death domain AAA_14 PF13173.6 EER27534.1 - 0.016 15.2 0.1 0.053 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EER27534.1 - 0.019 15.4 0.1 0.04 14.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain Hydin_ADK PF17213.3 EER27534.1 - 0.027 14.8 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Cytidylate_kin2 PF13189.6 EER27534.1 - 0.034 14.3 0.0 0.072 13.2 0.0 1.8 1 1 0 1 1 1 0 Cytidylate kinase-like family KTI12 PF08433.10 EER27534.1 - 0.035 13.6 0.0 0.076 12.4 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 dNK PF01712.19 EER27534.1 - 0.089 12.6 0.2 4.8 7.0 0.1 2.1 1 1 0 2 2 2 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 EER27534.1 - 0.12 12.1 0.1 0.22 11.2 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EER27534.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EER27534.1 - 0.15 11.8 0.7 8 6.1 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 EER27534.1 - 0.22 11.4 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_C78 PF07910.13 EER27535.1 - 1.1e-65 221.1 0.0 1.4e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 EER27535.1 - 0.0048 17.2 3.3 0.21 11.9 1.3 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 EER27535.1 - 0.0051 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger PSP PF04046.16 EER27535.1 - 0.11 12.4 1.9 0.4 10.6 0.0 2.7 3 1 0 3 3 3 0 PSP Peptidase_C39_2 PF13529.6 EER27535.1 - 0.16 12.5 0.0 0.52 10.8 0.0 1.9 2 0 0 2 2 2 0 Peptidase_C39 like family AA_kinase PF00696.28 EER27536.1 - 2e-38 132.4 0.3 3.7e-38 131.5 0.1 1.5 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.6 EER27536.1 - 5.3e-13 48.6 1.0 6.4e-11 41.9 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EER27536.1 - 1.3e-11 44.0 0.6 5e-09 35.8 0.1 2.7 2 0 0 2 2 2 2 ACT domain zf-Tim10_DDP PF02953.15 EER27537.1 - 4.3e-23 80.7 1.3 5.1e-23 80.5 1.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger G10 PF01125.17 EER27538.1 - 6e-69 230.5 5.9 6.7e-69 230.3 5.9 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 EER27539.1 - 1e-35 121.8 0.1 2.5e-35 120.6 0.1 1.7 1 0 0 1 1 1 1 Forkhead domain Ribosomal_L23eN PF03939.13 EER27540.1 - 1.5e-27 95.6 10.0 3e-27 94.6 10.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EER27540.1 - 1.9e-16 60.2 5.2 3.5e-16 59.3 1.7 2.1 2 0 0 2 2 2 1 Ribosomal protein L23 Linker_histone PF00538.19 EER27540.1 - 0.15 12.5 0.4 0.15 12.5 0.4 1.9 2 0 0 2 2 2 0 linker histone H1 and H5 family Bmt2 PF11968.8 EER27541.1 - 2.7e-90 302.0 0.0 3.3e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 eRF1_2 PF03464.15 EER27542.1 - 1.9e-46 157.6 0.0 3.3e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EER27542.1 - 1.7e-39 134.8 0.4 3.6e-39 133.7 0.4 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EER27542.1 - 4.5e-21 75.2 0.0 7.2e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EER27542.1 - 2.2e-09 37.7 0.0 3.8e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EER27542.1 - 1.3e-08 35.2 0.0 2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF3440 PF11922.8 EER27542.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Rad50_zn_hook PF04423.14 EER27542.1 - 0.18 11.7 0.2 33 4.4 0.0 2.9 2 0 0 2 2 2 0 Rad50 zinc hook motif PDT PF00800.18 EER27543.1 - 5.3e-61 205.6 0.0 6.7e-61 205.3 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EER27543.1 - 0.016 14.9 0.0 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 ACT domain MaoC_dehydratas PF01575.19 EER27544.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain BRF1 PF07741.13 EER27544.1 - 0.12 12.7 0.9 0.22 11.9 0.9 1.3 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DKCLD PF08068.12 EER27545.1 - 1.2e-33 115.0 0.2 2.6e-32 110.6 0.1 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 EER27545.1 - 2.4e-23 83.1 0.1 2e-20 73.7 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EER27545.1 - 1.2e-22 79.9 2.1 2.1e-22 79.0 2.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 EER27545.1 - 1.8e-21 75.9 1.8 3.2e-21 75.1 1.8 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EER27545.1 - 0.0037 17.5 0.0 0.0089 16.3 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain CLTH PF10607.9 EER27546.1 - 1e-35 122.8 0.0 1.7e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SKA2 PF16740.5 EER27546.1 - 0.0078 16.0 2.1 0.037 13.8 0.5 2.4 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 2 NRBF2 PF08961.10 EER27546.1 - 0.016 14.8 0.5 0.029 14.0 0.5 1.3 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator DNA_meth_N PF18284.1 EER27546.1 - 0.067 13.1 0.0 0.26 11.2 0.0 2.0 1 0 0 1 1 1 0 DNA methylase N-terminal domain EDR1 PF14381.6 EER27546.1 - 0.069 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 RseA_C PF03873.13 EER27546.1 - 0.14 12.4 0.6 0.64 10.3 0.6 2.2 1 1 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain zf-C2H2_9 PF16293.5 EER27546.1 - 0.26 11.2 2.0 0.35 10.7 0.1 2.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) TPR_4 PF07721.14 EER27546.1 - 1 10.2 3.8 1.2e+02 3.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2431 PF10354.9 EER27547.1 - 7.2e-60 202.1 0.0 1.1e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) EamA PF00892.20 EER27548.1 - 5.3e-07 29.9 7.2 5.3e-07 29.9 7.2 2.2 2 0 0 2 2 2 1 EamA-like transporter family PHO4 PF01384.20 EER27548.1 - 0.0024 17.0 3.5 0.0024 17.0 3.5 2.3 2 1 0 2 2 2 1 Phosphate transporter family UPF0370 PF13980.6 EER27548.1 - 0.16 12.1 0.8 0.47 10.5 0.1 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0370) RCDG1 PF15725.5 EER27548.1 - 4.9 7.6 6.3 13 6.3 6.3 1.6 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein Methyltr_RsmB-F PF01189.17 EER27549.1 - 1.3e-74 250.2 0.0 2e-74 249.6 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EER27549.1 - 1.1e-07 32.3 0.0 3.6e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EER27549.1 - 0.0012 19.0 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 EER27549.1 - 0.019 14.6 0.0 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Blt1 PF12754.7 EER27550.1 - 3.5e-63 212.4 0.0 6e-63 211.7 0.0 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 EER27550.1 - 3.5e-17 61.7 0.4 8.8e-17 60.4 0.4 1.7 2 0 0 2 2 2 1 Get5 carboxyl domain Ubiquitin_4 PF18036.1 EER27550.1 - 0.067 13.2 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Striatin PF08232.12 EER27551.1 - 2.4e-45 154.9 1.3 2.4e-45 154.9 1.3 1.7 2 0 0 2 2 2 1 Striatin family WD40 PF00400.32 EER27551.1 - 1.4e-25 89.0 21.2 7.5e-05 23.4 0.4 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27551.1 - 7.3e-05 23.0 0.1 0.65 10.3 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CALCOCO1 PF07888.11 EER27551.1 - 0.0039 16.1 2.4 0.0058 15.6 2.4 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Cytochrom_D1 PF02239.16 EER27551.1 - 0.073 11.6 0.0 0.16 10.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain ADH_N_2 PF16884.5 EER27551.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase eIF2A PF08662.11 EER27551.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A XPA_C PF05181.12 EER27552.1 - 1.9e-26 91.8 3.0 3.8e-26 90.8 3.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus YhfH PF14149.6 EER27552.1 - 0.00052 19.9 2.1 0.7 9.9 0.3 2.6 2 0 0 2 2 2 2 YhfH-like protein XPA_N PF01286.18 EER27552.1 - 0.0019 18.2 8.5 0.0019 18.2 8.5 2.1 2 0 0 2 2 2 1 XPA protein N-terminal PIG-P PF08510.12 EER27553.1 - 4.8e-53 178.2 1.5 8e-53 177.5 1.5 1.4 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EER27553.1 - 0.051 13.9 9.2 0.098 13.0 9.2 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MORN PF02493.20 EER27554.1 - 3.3e-14 51.8 23.4 0.0021 17.9 0.3 4.6 4 0 0 4 4 4 4 MORN repeat UCH PF00443.29 EER27554.1 - 1.4e-12 47.7 0.0 2.5e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.6 EER27554.1 - 3.4e-10 39.6 11.4 5.2e-10 39.0 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EER27554.1 - 0.0012 18.7 11.2 0.0021 17.8 11.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 USP7_ICP0_bdg PF12436.8 EER27554.1 - 0.0053 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-RING_5 PF14634.6 EER27554.1 - 0.34 10.9 12.6 0.6 10.1 12.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.17 EER27555.1 - 2e-132 440.8 0.0 2.3e-132 440.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.31 EER27556.1 - 1.1e-14 54.4 0.0 4.9e-08 33.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER27556.1 - 2.9e-05 24.2 0.2 0.3 11.4 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EER27556.1 - 0.0002 21.2 0.3 0.00096 19.0 0.0 2.3 2 0 0 2 2 2 1 Myb DNA-binding like MINDY_DUB PF04424.13 EER27557.1 - 1e-20 73.9 0.0 1.6e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 MINDY deubiquitinase CCDC24 PF15669.5 EER27557.1 - 0.26 11.1 6.3 8.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Gcd10p PF04189.13 EER27558.1 - 3.2e-122 407.4 0.0 4e-122 407.0 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Shugoshin_N PF07558.11 EER27558.1 - 0.055 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region PQ-loop PF04193.14 EER27559.1 - 0.35 10.7 0.0 0.35 10.7 0.0 2.9 4 0 0 4 4 4 0 PQ loop repeat P21-Arc PF04062.14 EER27560.1 - 2.5e-74 249.0 0.0 2.8e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Rep_fac_C PF08542.11 EER27561.1 - 8e-16 58.2 0.0 3.1e-15 56.3 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 EER27561.1 - 1.2e-15 58.1 0.5 2.4e-15 57.1 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EER27561.1 - 3.9e-13 49.5 0.0 1.8e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EER27561.1 - 4.6e-09 36.5 0.0 8.9e-09 35.5 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EER27561.1 - 1.9e-07 31.3 0.0 6.9e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 EER27561.1 - 1.4e-06 28.2 0.0 2.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EER27561.1 - 2.8e-06 27.7 0.1 2.9e-05 24.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EER27561.1 - 2.8e-06 27.2 0.1 7.6e-06 25.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EER27561.1 - 1.1e-05 25.9 0.1 0.00039 20.8 0.0 2.6 2 2 1 3 3 3 1 AAA ATPase domain AAA_11 PF13086.6 EER27561.1 - 2.4e-05 24.3 0.1 0.0001 22.2 0.0 1.8 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EER27561.1 - 3e-05 23.8 0.4 9.2e-05 22.2 0.0 2.0 3 0 0 3 3 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EER27561.1 - 0.00011 21.5 0.0 0.00019 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EER27561.1 - 0.00017 21.6 0.2 0.0014 18.7 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EER27561.1 - 0.0002 21.7 0.1 0.00052 20.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EER27561.1 - 0.00031 20.6 0.2 0.0028 17.5 0.1 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EER27561.1 - 0.00032 20.5 0.0 0.00059 19.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EER27561.1 - 0.0015 18.5 0.0 0.17 11.9 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EER27561.1 - 0.0019 17.7 0.3 0.4 10.1 0.0 2.4 1 1 1 2 2 2 1 PhoH-like protein DEAD PF00270.29 EER27561.1 - 0.0022 17.8 0.1 0.016 15.0 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_14 PF13173.6 EER27561.1 - 0.0023 18.0 0.0 0.0057 16.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EER27561.1 - 0.0078 16.8 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EER27561.1 - 0.016 15.4 0.0 0.03 14.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EER27561.1 - 0.021 14.2 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EER27561.1 - 0.027 14.0 0.0 0.088 12.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EER27561.1 - 0.037 13.7 0.0 0.088 12.5 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 EER27561.1 - 0.045 13.3 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 EER27561.1 - 0.063 12.7 0.1 0.2 11.0 0.1 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EER27561.1 - 0.065 13.0 0.0 0.46 10.2 0.0 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein ATPase_2 PF01637.18 EER27561.1 - 0.089 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 EER27561.1 - 0.095 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain MiaE PF06175.11 EER27561.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) RNA_helicase PF00910.22 EER27561.1 - 0.1 13.0 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EER27561.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) His_Phos_2 PF00328.22 EER27562.1 - 1.3e-07 31.4 0.0 5.7e-06 25.9 0.0 2.3 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) NQRA_SLBB PF11973.8 EER27562.1 - 0.078 13.6 0.0 0.2 12.3 0.0 1.7 1 0 0 1 1 1 0 NQRA C-terminal domain PlyB_C PF18684.1 EER27562.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Pleurotolysin B C-terminal domain Metallophos PF00149.28 EER27563.1 - 2.7e-07 31.3 0.2 3.6e-07 30.9 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pro_isomerase PF00160.21 EER27564.1 - 4.8e-37 127.7 0.0 9.8e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD R3H PF01424.22 EER27565.1 - 7.8e-12 45.0 1.2 1.5e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 R3H domain RRM_1 PF00076.22 EER27565.1 - 1.3e-05 24.9 0.1 2.6e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAS_C PF12026.8 EER27565.1 - 0.079 13.0 1.2 0.13 12.3 1.2 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Aldo_ket_red PF00248.21 EER27566.1 - 7.9e-21 74.5 0.0 4.5e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Aldo/keto reductase family CO_deh_flav_C PF03450.17 EER27566.1 - 0.072 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain HSF_DNA-bind PF00447.17 EER27567.1 - 4.3e-28 97.8 0.2 1.2e-27 96.3 0.2 1.8 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EER27567.1 - 0.045 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Ets-domain TMF_DNA_bd PF12329.8 EER27567.1 - 0.056 13.4 0.6 0.056 13.4 0.6 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding MRP-L28 PF09812.9 EER27567.1 - 1.1 9.4 6.7 0.58 10.3 2.4 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L28 Histone PF00125.24 EER27568.1 - 9.3e-17 61.6 0.0 1.2e-16 61.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EER27568.1 - 1e-11 44.4 0.0 2.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EER27568.1 - 3.7e-05 23.9 0.0 5.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pho88 PF10032.9 EER27569.1 - 2.9e-81 271.1 0.1 3.2e-81 270.9 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 EER27569.1 - 0.029 15.2 0.1 0.65 10.8 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) Gp_dh_C PF02800.20 EER27570.1 - 4.7e-71 237.5 0.1 6.9e-71 236.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EER27570.1 - 2.8e-40 136.7 0.0 7.8e-40 135.3 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EER27570.1 - 0.0054 16.8 0.1 0.029 14.5 0.0 2.3 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 EER27570.1 - 0.047 13.7 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EER27570.1 - 0.14 11.5 0.1 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Arb2 PF09757.9 EER27571.1 - 3e-98 328.1 0.9 4.8e-98 327.4 0.9 1.3 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EER27571.1 - 6.3e-87 291.9 0.0 1.1e-86 291.1 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Sugar_tr PF00083.24 EER27572.1 - 2.1e-125 419.1 24.4 2.4e-125 419.0 24.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER27572.1 - 2.6e-25 89.1 35.1 7.4e-18 64.6 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EER27572.1 - 2.5e-05 23.3 1.8 0.14 10.9 3.7 3.3 2 2 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 EER27573.1 - 8.1e-33 113.8 36.4 8.1e-33 113.8 36.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M16_M PF16187.5 EER27574.1 - 1e-95 320.2 0.7 1.6e-95 319.6 0.1 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EER27574.1 - 1.5e-32 113.1 0.2 1.8e-20 73.7 0.0 3.7 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EER27574.1 - 1.4e-30 106.2 9.5 1.7e-22 80.0 0.4 4.8 5 1 1 6 6 6 2 Insulinase (Peptidase family M16) DUF2315 PF10231.9 EER27574.1 - 0.02 15.0 1.7 4.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Apoptogenic protein 1 NUDIX_2 PF13869.6 EER27575.1 - 8.4e-82 273.3 0.0 1e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase SUKH-3 PF14433.6 EER27575.1 - 0.092 13.2 0.0 0.36 11.3 0.0 2.0 1 1 0 1 1 1 0 SUKH-3 immunity protein CoaE PF01121.20 EER27576.1 - 2.5e-42 144.6 0.0 4.6e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_33 PF13671.6 EER27576.1 - 0.003 17.7 0.0 0.027 14.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain TPR_10 PF13374.6 EER27576.1 - 0.021 14.7 0.3 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_18 PF13238.6 EER27576.1 - 0.03 14.9 0.2 0.26 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain MPP6 PF10175.9 EER27577.1 - 3.7e-07 30.7 4.6 3.9e-06 27.4 4.6 2.3 1 1 0 1 1 1 1 M-phase phosphoprotein 6 TarH PF02203.15 EER27577.1 - 0.0095 15.9 0.4 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 Tar ligand binding domain homologue OAD_gamma PF04277.13 EER27577.1 - 1.3 9.7 7.9 6.6 7.4 0.0 3.1 2 1 1 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF3499 PF12005.8 EER27577.1 - 6.4 7.4 6.5 13 6.4 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) zf-CHCC PF10276.9 EER27578.1 - 1.2e-16 60.4 0.7 2.1e-16 59.7 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.17 EER27579.1 - 3.8e-37 126.9 0.0 4.4e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 ECH_1 PF00378.20 EER27580.1 - 6.9e-49 166.4 0.0 8.9e-49 166.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER27580.1 - 1.4e-22 80.7 0.0 2.3e-20 73.4 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase FMO-like PF00743.19 EER27581.1 - 1.6e-14 53.2 0.1 1.6e-13 49.9 0.0 2.4 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EER27581.1 - 1.8e-05 24.9 0.1 8.1e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EER27581.1 - 0.00011 21.5 0.0 0.00034 19.9 0.0 1.9 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EER27581.1 - 0.00077 18.8 0.0 0.032 13.5 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER27581.1 - 0.062 12.6 0.0 0.55 9.4 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER27581.1 - 0.071 13.1 0.0 1.3 9.0 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding PQQ_3 PF13570.6 EER27582.1 - 1.3 9.6 9.7 4.1 8.0 0.3 3.9 5 0 0 5 5 5 0 PQQ-like domain zf-CHY PF05495.12 EER27583.1 - 1.3e-10 41.6 17.2 2.5e-10 40.7 17.2 1.5 1 0 0 1 1 1 1 CHY zinc finger Evr1_Alr PF04777.13 EER27583.1 - 0.21 12.1 9.8 1.6 9.2 9.8 2.1 1 1 0 1 1 1 0 Erv1 / Alr family HypA PF01155.19 EER27583.1 - 3.2 7.8 11.5 9 6.4 11.5 1.9 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Proteasome PF00227.26 EER27584.1 - 2e-56 190.5 0.1 2.8e-56 190.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EER27584.1 - 6e-13 48.2 0.3 2.1e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 EER27584.1 - 0.0091 15.9 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) AMP-binding PF00501.28 EER27585.1 - 3.2e-76 256.6 0.0 3.9e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER27585.1 - 2.2e-16 60.6 0.2 4.7e-16 59.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4048 PF13257.6 EER27586.1 - 7.6e-81 271.7 17.6 1.5e-80 270.7 17.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4048) Bap31_Bap29_C PF18035.1 EER27586.1 - 0.15 12.1 2.0 0.29 11.2 2.0 1.5 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Pkinase PF00069.25 EER27587.1 - 8.4e-70 235.1 0.0 1.5e-69 234.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27587.1 - 1.4e-47 162.2 0.0 2.2e-47 161.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER27587.1 - 2.2e-06 26.7 0.2 1.5e-05 24.0 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EER27587.1 - 2e-05 24.0 0.0 0.00027 20.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Glycos_transf_2 PF00535.26 EER27587.1 - 0.07 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Haspin_kinase PF12330.8 EER27587.1 - 0.082 11.8 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain FAD-oxidase_C PF02913.19 EER27588.1 - 1.1e-59 202.0 0.0 1.5e-59 201.6 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EER27588.1 - 1.4e-35 122.0 0.3 2.7e-35 121.1 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Tim17 PF02466.19 EER27589.1 - 1.6e-39 134.7 6.3 1.6e-39 134.7 6.3 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Oxidored_molyb PF00174.19 EER27590.1 - 2.8e-58 196.4 0.0 4.2e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EER27590.1 - 1.2e-22 80.4 1.5 2.3e-22 79.5 1.5 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Abhydrolase_6 PF12697.7 EER27591.1 - 1.6e-09 38.7 0.4 1.8e-09 38.5 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EER27591.1 - 0.00025 21.2 0.0 0.00032 20.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 EER27591.1 - 0.004 16.5 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EER27591.1 - 0.12 11.3 0.0 0.25 10.2 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_9_N PF15420.6 EER27592.1 - 0.057 13.4 0.6 1.9 8.4 0.3 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus PALP PF00291.25 EER27593.1 - 5.6e-68 229.5 0.3 5.6e-68 229.5 0.3 1.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.7 EER27594.1 - 3.6e-92 308.7 0.9 6.2e-91 304.6 0.0 3.0 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EER27594.1 - 4.5e-09 36.6 7.6 0.00016 22.0 0.5 4.6 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 EER27594.1 - 8.8e-07 29.3 2.3 0.31 11.6 0.1 5.7 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 EER27594.1 - 3.4e-06 26.8 5.0 0.34 11.3 0.0 6.5 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EER27594.1 - 0.00032 20.8 1.8 0.15 12.1 0.1 4.0 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 EER27594.1 - 0.13 11.9 1.2 1.8 8.1 0.0 3.3 4 1 1 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 EER27594.1 - 0.13 12.5 0.2 6 7.1 0.0 3.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RICTOR_N PF14664.6 EER27594.1 - 0.3 10.0 1.6 1.8 7.5 0.6 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term zf-RanBP PF00641.18 EER27595.1 - 2.4e-19 68.3 8.1 6.9e-10 38.1 1.5 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EER27595.1 - 3.8e-08 33.0 0.0 8.4e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EER27595.1 - 1e-05 26.2 0.0 1.5e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.7 EER27595.1 - 3.2 7.9 6.1 2.7 8.1 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon F-box-like PF12937.7 EER27596.1 - 1.7e-08 34.2 1.2 3.7e-08 33.1 1.2 1.6 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 EER27597.1 - 0.00031 20.2 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EER27597.1 - 0.00065 19.1 0.0 0.001 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 EER27597.1 - 0.05 13.2 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 EER27597.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH PF00169.29 EER27598.1 - 0.0022 18.5 0.1 0.0048 17.4 0.1 1.5 1 0 0 1 1 1 1 PH domain RmlD_sub_bind PF04321.17 EER27599.1 - 3.6e-45 154.3 0.0 4.7e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EER27599.1 - 8.2e-17 61.5 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EER27599.1 - 1.6e-07 30.8 0.0 3.9e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EER27599.1 - 2.6e-07 30.4 0.1 3.9e-07 29.8 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EER27599.1 - 2.8e-07 29.9 0.1 1.4e-06 27.5 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EER27599.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EER27599.1 - 0.02 14.0 0.2 1.2 8.2 0.1 2.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein TrkH PF02386.16 EER27601.1 - 3.5e-143 477.7 8.6 1.1e-141 472.8 6.1 2.1 2 0 0 2 2 2 2 Cation transport protein Dynamin_M PF01031.20 EER27602.1 - 2.9e-101 338.5 0.0 5.5e-101 337.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EER27602.1 - 3e-57 193.4 0.2 6.4e-57 192.3 0.2 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EER27602.1 - 2e-30 104.8 5.4 4.8e-30 103.6 5.4 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EER27602.1 - 4.2e-06 26.8 0.5 9.6e-05 22.4 0.5 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EER27602.1 - 0.0094 15.7 5.0 1.1 8.9 0.3 2.6 3 0 0 3 3 3 2 AAA ATPase domain ATP-synt_ab PF00006.25 EER27603.1 - 1.3e-108 361.5 0.0 2.1e-108 360.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EER27603.1 - 2.6e-46 156.4 0.0 5e-46 155.5 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EER27603.1 - 1.9e-15 57.1 3.1 4e-15 56.1 3.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EER27603.1 - 0.12 11.5 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain RVT_2 PF07727.14 EER27604.1 - 6.1e-51 173.4 0.0 9.3e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EER27604.1 - 2.1e-14 53.7 0.0 1.1e-13 51.4 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EER27604.1 - 3.9e-06 26.6 0.1 9.8e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 EER27604.1 - 0.001 19.0 1.7 0.0022 18.0 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 EER27604.1 - 0.0027 17.4 0.0 0.0084 15.8 0.0 1.9 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 EER27604.1 - 0.079 12.7 0.1 2.7 7.8 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain Neugrin PF06413.11 EER27604.1 - 0.14 12.2 6.2 0.32 11.0 4.9 2.3 2 0 0 2 2 2 0 Neugrin WD40 PF00400.32 EER27605.1 - 2.7e-27 94.5 15.4 2.9e-05 24.7 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27605.1 - 9.9e-16 57.8 0.2 0.014 15.7 0.0 5.3 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER27605.1 - 4.8e-06 25.5 0.6 7.5e-05 21.6 0.2 2.3 1 1 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EER27605.1 - 9.7e-06 24.8 0.3 0.0039 16.2 0.7 3.5 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EER27605.1 - 3e-05 22.7 0.0 0.013 14.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EER27605.1 - 4.5e-05 23.4 0.0 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.9 EER27605.1 - 0.00015 21.7 0.1 0.00025 21.0 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Frtz PF11768.8 EER27605.1 - 0.0022 16.4 0.0 1.4 7.2 0.0 2.3 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 EER27605.1 - 0.0042 17.0 1.7 16 5.6 0.0 4.4 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat DEAD PF00270.29 EER27606.1 - 3e-42 144.4 0.2 5.2e-42 143.6 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER27606.1 - 2.2e-33 114.9 0.1 6.5e-33 113.4 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER27606.1 - 2.8e-05 24.2 0.0 4.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EER27606.1 - 0.00023 21.0 0.1 0.00034 20.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EER27606.1 - 0.00085 19.7 0.1 0.0082 16.5 0.1 2.2 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EER27606.1 - 0.015 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Helicase UTP25 PF06862.12 EER27606.1 - 0.018 13.9 0.0 3.8 6.2 0.0 2.1 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Flavi_DEAD PF07652.14 EER27606.1 - 0.018 15.0 0.2 0.078 13.0 0.0 2.2 2 1 1 3 3 3 0 Flavivirus DEAD domain DsrH PF04077.12 EER27606.1 - 0.022 14.9 0.2 4.2 7.6 0.1 2.6 2 0 0 2 2 2 0 DsrH like protein TniB PF05621.11 EER27606.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein UvrD-helicase PF00580.21 EER27606.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EER27606.1 - 0.35 11.1 1.5 1.9 8.8 1.5 2.1 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 EER27607.1 - 7.1e-78 260.6 1.5 3.3e-77 258.5 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EER27607.1 - 3.4e-25 88.4 2.2 3.4e-25 88.4 2.2 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EER27607.1 - 1.5e-15 56.7 1.2 3.6e-15 55.5 1.2 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EER27607.1 - 7.1e-08 32.5 2.8 4.6e-07 30.0 1.8 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER27607.1 - 2.4e-07 30.9 2.8 6e-06 26.5 1.7 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EER27607.1 - 0.00021 21.6 0.2 0.0044 17.3 0.1 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) PRP9_N PF16958.5 EER27607.1 - 0.049 13.7 13.5 0.18 11.8 0.1 3.7 3 1 1 4 4 4 0 Pre-mRNA-splicing factor PRP9 N-terminus zf-LYAR PF08790.11 EER27607.1 - 0.09 12.7 0.3 0.22 11.4 0.3 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 EER27607.1 - 0.12 13.3 0.8 5.2 8.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EER27607.1 - 2.5 8.7 4.1 2.8 8.6 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type DNA_ligase_A_M PF01068.21 EER27608.1 - 9.3e-25 87.5 0.0 1.4e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EER27608.1 - 1.3e-18 67.9 0.0 2.9e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus LBP_M PF17385.2 EER27608.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase central domain ANAPC8 PF04049.13 EER27609.1 - 7.9e-54 181.5 0.1 7.9e-54 181.5 0.1 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EER27609.1 - 3e-22 77.4 12.3 0.00018 21.1 0.0 8.4 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EER27609.1 - 7.3e-21 72.6 19.8 1.8e-05 24.6 0.0 9.2 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 EER27609.1 - 1.2e-19 68.7 28.8 0.1 12.7 0.0 9.7 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 EER27609.1 - 3.6e-13 49.1 27.5 0.0072 17.1 0.0 9.3 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EER27609.1 - 5.3e-12 45.8 18.1 0.039 14.2 0.0 7.8 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EER27609.1 - 9.5e-11 41.2 2.6 1.1e-06 28.2 0.3 4.5 2 2 2 4 4 4 2 TPR repeat TPR_19 PF14559.6 EER27609.1 - 4.2e-10 40.0 16.2 0.14 12.7 0.0 7.9 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 EER27609.1 - 1.3e-09 38.6 25.8 1.7e-05 25.3 0.0 7.6 8 1 0 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EER27609.1 - 2e-08 34.4 17.0 0.14 12.4 0.2 6.2 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EER27609.1 - 9.1e-08 32.0 6.5 1.2 9.6 0.1 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER27609.1 - 1.1e-06 28.2 11.0 0.24 11.5 0.2 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EER27609.1 - 4.1e-06 26.8 20.8 0.0016 18.5 0.4 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EER27609.1 - 0.00021 21.7 30.9 2 9.2 0.4 9.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_15 PF13429.6 EER27609.1 - 0.0013 18.0 12.9 0.0038 16.5 2.9 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF3856 PF12968.7 EER27609.1 - 0.98 9.5 4.1 1.2 9.2 0.1 3.0 2 1 1 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_MalT PF17874.1 EER27609.1 - 1.6 8.1 7.3 0.45 9.8 0.6 2.9 4 0 0 4 4 4 0 MalT-like TPR region TPR_3 PF07720.12 EER27609.1 - 3.4 7.8 7.7 0.58 10.2 0.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EER27609.1 - 9.7 6.2 23.3 3.3 7.7 0.5 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 EER27610.1 - 2.9e-87 291.9 0.0 3.6e-87 291.7 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase LolA_2 PF16584.5 EER27610.1 - 0.22 11.4 0.1 0.36 10.7 0.1 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Glycogen_syn PF05693.13 EER27611.1 - 0 1136.4 0.0 0 1136.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 EER27611.1 - 2.3e-05 24.5 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EER27611.1 - 2.7e-05 23.8 0.0 0.0037 16.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EER27611.1 - 3.3e-05 24.3 0.0 0.026 15.0 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EER27611.1 - 0.00033 20.4 0.0 0.00056 19.7 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 EER27611.1 - 0.0013 19.2 0.0 0.0029 18.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Vps54 PF07928.12 EER27613.1 - 8.4e-52 175.2 1.3 3.4e-51 173.2 0.4 2.5 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 EER27613.1 - 1.5e-06 27.7 0.8 5.7e-06 25.8 0.8 1.9 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EER27613.1 - 6.3e-05 22.9 0.2 0.00022 21.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Dynamin_M PF01031.20 EER27613.1 - 0.1 11.8 0.1 0.44 9.7 0.0 2.2 2 1 0 2 2 2 0 Dynamin central region MCM PF00493.23 EER27614.1 - 3.5e-104 346.8 0.0 6.9e-104 345.8 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EER27614.1 - 1.2e-36 125.3 0.9 2.2e-36 124.5 0.9 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EER27614.1 - 3.6e-28 97.8 3.2 5.7e-28 97.2 2.0 2.0 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EER27614.1 - 5.6e-16 59.0 0.5 1.2e-15 57.9 0.5 1.5 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EER27614.1 - 7.1e-07 28.8 0.0 0.00014 21.4 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EER27614.1 - 2.1e-05 24.5 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EER27614.1 - 0.00063 19.6 0.1 0.0027 17.6 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EER27614.1 - 0.042 13.5 0.1 0.56 9.9 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain ECH_1 PF00378.20 EER27615.1 - 1.1e-33 116.6 0.0 1.4e-30 106.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER27615.1 - 2e-16 60.4 0.0 3.6e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase PfkB PF00294.24 EER27616.1 - 6e-41 140.7 0.0 9.7e-41 140.0 0.0 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase NYAP_N PF15439.6 EER27616.1 - 0.0091 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Tau95 PF09734.9 EER27618.1 - 3.3e-43 147.9 0.4 3.3e-43 147.9 0.4 1.7 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EER27618.1 - 4e-32 111.1 0.4 7.3e-32 110.2 0.0 1.7 2 0 0 2 2 2 1 Tau95 Triple barrel domain Nop14 PF04147.12 EER27618.1 - 9.6 4.3 11.0 12 4.0 11.0 1.1 1 0 0 1 1 1 0 Nop14-like family B56 PF01603.20 EER27619.1 - 2.1e-192 639.7 3.0 2.5e-192 639.4 3.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FAT PF02259.23 EER27620.1 - 1.7e-72 244.5 7.6 3.6e-72 243.5 7.6 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EER27620.1 - 2.1e-33 116.2 0.7 9.8e-33 114.0 0.2 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EER27620.1 - 0.00047 19.9 0.2 0.0012 18.6 0.2 1.7 1 0 0 1 1 1 1 FATC domain CLASP_N PF12348.8 EER27620.1 - 0.14 11.7 1.6 7 6.1 0.1 3.8 4 0 0 4 4 4 0 CLASP N terminal DUF572 PF04502.13 EER27621.1 - 2.8e-69 234.3 10.1 3.2e-69 234.1 10.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.13 EER27621.1 - 0.054 13.4 0.8 0.092 12.6 0.8 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) DUF951 PF06107.11 EER27621.1 - 0.075 13.0 0.2 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) DNA_RNApol_7kD PF03604.13 EER27621.1 - 0.11 12.2 2.4 7.8 6.3 0.4 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit zf-FCS PF06467.14 EER27621.1 - 0.21 11.6 4.0 0.85 9.6 0.2 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_2 PF13240.6 EER27621.1 - 0.87 9.4 3.6 1.2 9.0 0.7 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 EER27621.1 - 0.93 9.6 3.6 3.4 7.8 0.8 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain TF_Zn_Ribbon PF08271.12 EER27621.1 - 1.7 8.2 6.3 3.1 7.4 1.6 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 EER27621.1 - 4.8 7.4 7.0 23 5.2 0.1 3.1 2 1 1 3 3 3 0 Zinc ribbon domain TPR_1 PF00515.28 EER27622.1 - 2e-27 93.8 5.8 0.00034 20.3 0.8 10.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 EER27622.1 - 1.1e-26 90.7 12.6 0.0006 19.7 0.5 10.6 10 0 0 10 10 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EER27622.1 - 2.7e-24 85.2 19.3 9.5e-22 77.0 1.6 5.8 6 0 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EER27622.1 - 3.1e-19 69.2 11.3 0.00039 20.9 0.0 7.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 EER27622.1 - 2.8e-17 62.8 29.4 1.2e-06 28.7 0.1 10.3 8 3 1 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 EER27622.1 - 3.1e-16 58.1 6.3 0.083 13.1 0.1 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 EER27622.1 - 4.1e-11 42.7 18.2 2.4 9.2 0.3 9.9 7 3 3 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EER27622.1 - 5.3e-11 43.0 26.6 0.36 11.5 0.0 9.5 9 1 2 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 EER27622.1 - 3.4e-10 39.4 1.9 0.39 10.5 0.1 7.6 8 1 1 9 9 9 2 TPR repeat TPR_6 PF13174.6 EER27622.1 - 2.3e-08 34.2 9.8 0.45 11.3 0.4 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER27622.1 - 5.3e-07 29.2 20.5 13 6.1 0.0 9.5 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_10 PF13374.6 EER27622.1 - 6.8e-07 29.0 15.2 0.0041 16.9 0.0 7.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_21 PF09976.9 EER27622.1 - 0.0011 18.7 3.1 3.9 7.1 0.0 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 EER27622.1 - 0.0014 18.8 13.7 5.1 7.7 0.0 8.2 9 1 1 10 10 10 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EER27622.1 - 0.058 13.4 0.1 0.31 11.1 0.1 2.3 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_4 PF07721.14 EER27622.1 - 0.71 10.7 27.1 0.67 10.7 0.1 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat Fungal_trans PF04082.18 EER27623.1 - 1.2e-11 44.2 0.2 3e-11 42.9 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER27623.1 - 2e-06 27.8 12.2 4e-06 26.8 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DinB_2 PF12867.7 EER27623.1 - 0.14 12.7 0.2 1.3 9.5 0.2 2.3 1 1 0 1 1 1 0 DinB superfamily MFS_1 PF07690.16 EER27624.1 - 4.9e-42 144.1 30.6 4.9e-42 144.1 30.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER27624.1 - 5.2e-11 41.7 4.1 8.9e-11 40.9 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER27624.1 - 4.7e-10 38.9 30.6 1.3e-09 37.5 30.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EER27624.1 - 0.0039 16.5 3.4 0.0039 16.5 3.4 2.8 3 1 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB GATase_5 PF13507.6 EER27625.1 - 7.3e-100 333.3 0.0 1.2e-99 332.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EER27625.1 - 3.8e-38 131.1 0.2 2.4e-24 86.2 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EER27625.1 - 1.9e-35 121.3 0.0 3.4e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EER27625.1 - 2e-21 76.3 0.0 4.7e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Tegument_dsDNA PF12818.7 EER27625.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein GCP_N_terminal PF17681.1 EER27626.1 - 3.1e-34 119.0 0.2 6.9e-34 117.9 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EER27626.1 - 9.6e-27 94.2 4.3 1.9e-26 93.2 4.3 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Glyco_transf_15 PF01793.16 EER27627.1 - 1.9e-112 375.7 12.9 2.4e-112 375.4 12.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5A PF02284.16 EER27628.1 - 1.9e-39 133.8 0.4 2.4e-39 133.5 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF488 PF04343.13 EER27628.1 - 0.088 13.4 1.3 2 9.0 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF488 ELO PF01151.18 EER27629.1 - 2.7e-63 213.8 19.7 3.2e-63 213.6 19.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family AA_permease_2 PF13520.6 EER27631.1 - 1.5e-42 145.9 36.7 2e-42 145.5 36.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER27631.1 - 3.8e-19 68.6 31.4 5.2e-19 68.2 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.6 EER27632.1 - 3.9e-62 209.9 0.0 5.1e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER27632.1 - 2.2e-51 174.1 0.5 2.7e-51 173.8 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER27632.1 - 3.7e-05 23.7 0.7 0.0001 22.3 0.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EER27632.1 - 0.015 14.8 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EER27632.1 - 0.068 13.9 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 EER27632.1 - 0.39 10.8 2.6 0.64 10.1 2.7 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1996 PF09362.10 EER27633.1 - 3e-85 286.0 0.0 3.9e-85 285.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) 2-Hacid_dh_C PF02826.19 EER27635.1 - 8.8e-46 155.5 0.0 1.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER27635.1 - 1.1e-08 34.8 0.0 5.8e-08 32.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EER27635.1 - 5.8e-06 26.6 0.1 1.5e-05 25.2 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EER27635.1 - 0.0046 17.5 0.0 0.0092 16.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EER27635.1 - 0.033 13.7 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Asparaginase PF00710.20 EER27636.1 - 6.2e-58 195.5 0.0 9.2e-58 194.9 0.0 1.2 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EER27636.1 - 1.5e-26 92.8 0.1 2.8e-26 92.0 0.1 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EER27636.1 - 5.2e-11 43.0 0.1 1.5e-10 41.5 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EER27636.1 - 4.7e-08 32.7 1.0 0.0033 17.8 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EER27636.1 - 1.2e-07 32.1 0.3 0.00066 20.2 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EER27636.1 - 1.7e-07 31.4 2.6 0.00012 22.3 0.3 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EER27636.1 - 8.9e-07 29.1 0.3 2.6e-06 27.6 0.3 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) MTTB PF06253.11 EER27636.1 - 0.033 12.2 0.1 0.044 11.8 0.1 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) NmrA PF05368.13 EER27637.1 - 1.1e-74 250.9 0.0 1.4e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EER27637.1 - 4.5e-07 29.9 0.0 7.6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1876 PF08962.11 EER27637.1 - 0.14 12.2 0.2 0.26 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) NAP PF00956.18 EER27638.1 - 2.8e-24 85.7 10.8 2.1e-21 76.3 10.3 2.2 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.11 EER27639.1 - 1e-26 93.4 1.2 7.6e-26 90.6 0.1 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EER27639.1 - 0.0011 18.9 1.2 0.0029 17.5 1.2 1.8 1 0 0 1 1 1 1 SNARE domain APG17 PF04108.12 EER27639.1 - 0.0018 17.5 0.8 0.17 11.0 0.1 2.2 2 0 0 2 2 2 2 Autophagy protein Apg17 Use1 PF09753.9 EER27639.1 - 0.025 14.3 0.0 0.036 13.8 0.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 GCIP PF13324.6 EER27639.1 - 0.037 13.6 4.7 0.42 10.2 1.8 2.3 2 1 0 2 2 2 0 Grap2 and cyclin-D-interacting KxDL PF10241.9 EER27639.1 - 0.066 13.5 3.6 40 4.6 0.1 3.7 3 2 1 4 4 4 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.7 EER27639.1 - 0.12 12.6 8.7 0.3 11.2 1.5 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF5089 PF17002.5 EER27639.1 - 0.17 11.7 1.2 0.22 11.4 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) DUF3618 PF12277.8 EER27639.1 - 0.18 12.1 13.4 1.2 9.4 0.7 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DUF2072 PF09845.9 EER27639.1 - 0.3 11.4 1.3 1.5 9.1 0.3 2.1 1 1 1 2 2 2 0 Zn-ribbon containing protein NPV_P10 PF05531.12 EER27639.1 - 0.44 11.0 5.2 1.8 9.1 0.1 3.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2650 PF10853.8 EER27639.1 - 0.51 10.1 2.9 0.77 9.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) DUF883 PF05957.13 EER27639.1 - 0.56 10.9 4.1 7 7.3 0.0 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) HMMR_N PF15905.5 EER27639.1 - 0.88 9.0 4.7 0.56 9.6 0.4 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Methyltransf_32 PF13679.6 EER27640.1 - 5.8e-22 78.4 0.1 3e-21 76.0 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain PTR2 PF00854.21 EER27641.1 - 4e-81 272.9 8.2 5.3e-81 272.5 8.2 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EER27641.1 - 1.9e-09 36.9 19.3 5.7e-09 35.4 19.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER27641.1 - 0.059 12.2 19.6 0.11 11.3 9.5 3.3 3 1 0 3 3 3 0 Sugar (and other) transporter Ank_2 PF12796.7 EER27642.1 - 2.3e-39 133.9 1.1 2.7e-09 37.5 0.0 7.4 4 1 2 7 7 7 6 Ankyrin repeats (3 copies) Pkinase PF00069.25 EER27642.1 - 4.5e-28 98.4 0.0 7.3e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27642.1 - 1.6e-24 86.6 0.0 4e-24 85.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_3 PF13606.6 EER27642.1 - 6.3e-24 81.4 8.7 0.00031 20.9 0.0 10.7 11 0 0 11 11 11 5 Ankyrin repeat Ank_5 PF13857.6 EER27642.1 - 3e-23 81.6 8.6 7.3e-07 29.3 0.0 8.8 6 3 3 9 9 9 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EER27642.1 - 3.8e-23 81.5 8.0 0.00074 20.0 0.0 9.1 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank PF00023.30 EER27642.1 - 2.1e-17 62.7 8.5 0.00057 20.2 0.0 9.2 9 0 0 9 9 9 4 Ankyrin repeat Sel1 PF08238.12 EER27642.1 - 0.019 15.6 0.0 0.067 13.9 0.0 2.1 1 0 0 1 1 1 0 Sel1 repeat Pkinase_Tyr PF07714.17 EER27643.1 - 1.6e-07 30.9 0.0 2.5e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EER27643.1 - 8e-07 28.7 0.0 1.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LCCL PF03815.19 EER27644.1 - 2.8e-21 75.4 0.3 4.1e-21 74.9 0.3 1.2 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.21 EER27645.1 - 3.1e-12 46.3 0.0 5e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II UPF0029 PF01205.19 EER27646.1 - 6.2e-36 122.9 0.1 1.2e-35 122.0 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EER27646.1 - 1.5e-07 31.7 0.0 3.1e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 RWD domain DUF4113 PF13438.6 EER27646.1 - 0.06 13.4 0.4 0.33 11.1 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4113) Glyco_hydro_61 PF03443.14 EER27647.1 - 7.3e-05 22.8 0.0 0.00028 20.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Ribosomal_L4 PF00573.22 EER27648.1 - 3.9e-37 127.8 0.1 5.4e-37 127.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EER27648.1 - 1.9e-31 107.9 0.9 4.4e-31 106.8 0.9 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain NAAA-beta PF15508.6 EER27649.1 - 4.8e-16 58.8 0.1 9.7e-16 57.8 0.1 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3395 PF11875.8 EER27650.1 - 8.6e-43 145.9 0.3 1.4e-42 145.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EER27650.1 - 5.3e-15 55.3 0.3 1.2e-14 54.2 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain SKIP_SNW PF02731.15 EER27653.1 - 1.4e-71 239.4 6.3 1.4e-71 239.4 6.3 2.4 2 0 0 2 2 2 1 SKIP/SNW domain LMBR1 PF04791.16 EER27653.1 - 9.9 4.9 4.9 13 4.5 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.32 EER27654.1 - 4.3e-39 131.8 20.4 2.8e-08 34.3 0.2 12.6 13 0 0 13 13 13 6 WD domain, G-beta repeat Utp12 PF04003.12 EER27654.1 - 5.1e-29 100.7 0.0 7.8e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EER27654.1 - 7.9e-21 74.2 0.0 0.0018 18.5 0.0 9.0 5 2 4 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EER27654.1 - 7.8e-10 38.2 1.9 0.33 9.9 0.0 5.9 5 2 2 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EER27654.1 - 8.7e-07 29.0 1.1 0.014 15.3 0.1 5.7 4 1 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EER27654.1 - 9.1e-05 21.3 4.8 0.24 10.0 0.0 5.1 4 2 1 5 5 5 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 EER27654.1 - 0.00057 19.3 0.1 8.3 5.6 0.0 3.8 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EER27654.1 - 0.049 13.0 0.0 0.38 10.0 0.0 2.5 4 0 0 4 4 4 0 WD40-like domain ELYS-bb PF16687.5 EER27654.1 - 0.14 10.8 0.2 2 7.0 0.0 2.8 4 0 0 4 4 4 0 beta-propeller of ELYS nucleoporin PQQ_3 PF13570.6 EER27654.1 - 0.32 11.6 5.4 56 4.4 0.0 5.2 6 0 0 6 6 6 0 PQQ-like domain Septin PF00735.18 EER27655.1 - 5.7e-116 386.7 0.4 9.4e-116 386.0 0.4 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EER27655.1 - 1.8e-07 31.2 0.0 4.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER27655.1 - 4.7e-06 26.3 4.4 5.9e-05 22.7 0.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EER27655.1 - 4.9e-06 26.6 1.3 5e-05 23.3 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase Pox_A32 PF04665.12 EER27655.1 - 0.0029 17.1 0.1 0.0052 16.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 EER27655.1 - 0.0034 17.6 1.0 0.01 16.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain Roc PF08477.13 EER27655.1 - 0.0037 17.5 0.1 0.0087 16.3 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Casc1_N PF15927.5 EER27655.1 - 0.0041 16.8 10.6 0.012 15.3 10.6 1.8 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus IIGP PF05049.13 EER27655.1 - 0.0084 15.2 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 EER27655.1 - 0.012 15.0 0.0 0.026 13.8 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_24 PF13479.6 EER27655.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EER27655.1 - 0.021 14.4 0.7 0.066 12.8 0.4 2.0 2 1 0 2 2 2 0 Ras family ABC_tran PF00005.27 EER27655.1 - 0.026 15.1 0.2 0.17 12.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EER27655.1 - 0.027 14.8 1.9 0.072 13.5 0.1 2.5 2 1 0 2 2 2 0 AAA ATPase domain T2SSE PF00437.20 EER27655.1 - 0.033 13.3 0.4 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 EER27655.1 - 0.036 13.3 0.0 0.048 12.9 0.0 1.5 1 1 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.6 EER27655.1 - 0.04 13.5 0.3 0.48 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain FOXP-CC PF16159.5 EER27655.1 - 0.044 14.4 0.7 0.044 14.4 0.7 2.3 2 1 1 3 3 1 0 FOXP coiled-coil domain NACHT PF05729.12 EER27655.1 - 0.051 13.5 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Exonuc_VII_L PF02601.15 EER27655.1 - 0.06 12.9 3.4 0.13 11.9 3.4 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_27 PF13514.6 EER27655.1 - 0.077 12.6 2.6 0.26 10.9 0.7 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EER27655.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EER27655.1 - 0.14 11.9 0.4 5 6.9 0.4 2.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EER27655.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Dynamin_N PF00350.23 EER27655.1 - 0.43 10.6 6.7 4.4 7.3 0.1 3.2 2 1 1 3 3 3 0 Dynamin family AAA_11 PF13086.6 EER27655.1 - 3.8 7.2 7.6 24 4.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myc-LZ PF02344.15 EER27655.1 - 7.1 6.8 10.1 7.9 6.7 3.9 3.2 2 1 0 2 2 2 0 Myc leucine zipper domain WD40 PF00400.32 EER27656.1 - 1.8e-22 79.2 14.5 8.8e-05 23.2 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27656.1 - 1.2e-11 44.7 1.9 0.012 15.8 0.0 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 EER27656.1 - 7.6e-06 25.6 0.3 0.011 15.6 0.0 4.0 4 0 0 4 4 4 1 PQQ enzyme repeat VID27 PF08553.10 EER27656.1 - 0.00037 19.7 0.2 0.0032 16.6 0.1 2.2 2 1 0 2 2 2 1 VID27 C-terminal WD40-like domain BAT PF15915.5 EER27656.1 - 0.017 15.0 4.7 0.052 13.4 4.3 2.0 1 1 1 2 2 2 0 GAF and HTH_10 associated domain Ge1_WD40 PF16529.5 EER27656.1 - 0.09 11.7 0.5 0.6 9.0 0.0 2.5 4 1 1 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 EER27656.1 - 0.14 11.2 1.0 9.7 5.2 0.0 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1513) XRN_M PF17846.1 EER27657.1 - 2.1e-101 340.1 3.5 3.6e-101 339.3 3.5 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EER27657.1 - 4.6e-98 327.5 0.0 9e-98 326.5 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EER27657.1 - 7.2e-79 264.0 0.0 7.2e-79 264.0 0.0 2.3 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EER27657.1 - 2.8e-33 114.0 1.3 4.3e-33 113.4 0.0 2.1 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EER27657.1 - 4.2e-23 81.2 0.3 9.1e-23 80.1 0.3 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EER27657.1 - 7.5e-10 38.8 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 DUF4604 PF15377.6 EER27657.1 - 0.11 12.9 1.7 0.36 11.2 1.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Peptidase_C92 PF05708.12 EER27657.1 - 0.21 11.7 0.3 0.45 10.6 0.3 1.5 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Noggin PF05806.12 EER27657.1 - 0.3 11.0 0.6 0.64 9.9 0.6 1.5 1 0 0 1 1 1 0 Noggin DUF4603 PF15376.6 EER27657.1 - 2.4 5.4 5.3 3.8 4.8 5.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CAF1C_H4-bd PF12265.8 EER27658.1 - 1.3e-28 99.0 0.9 7e-28 96.7 1.1 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EER27658.1 - 2.3e-28 97.8 9.9 1.2e-05 25.9 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27658.1 - 1.3e-07 31.8 1.2 0.0082 16.4 0.1 4.6 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain GTP_cyclohydroI PF01227.22 EER27659.1 - 7.4e-73 243.8 0.2 1e-72 243.3 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EER27659.1 - 0.0024 18.0 0.0 0.007 16.5 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein Cadherin_3 PF16184.5 EER27660.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Cadherin-like Questin_oxidase PF14027.6 EER27661.1 - 9.7e-99 331.1 0.1 1.2e-98 330.8 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like MFA1_2 PF17317.2 EER27661.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Mating hormone A-factor 1&2 Pkinase PF00069.25 EER27662.1 - 9.8e-12 44.8 0.0 6.3e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER27662.1 - 0.0025 17.1 0.0 0.49 9.6 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EER27662.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EER27662.1 - 0.18 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EER27663.1 - 8e-70 235.2 0.0 1.3e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27663.1 - 4.6e-33 114.6 0.0 8.6e-33 113.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER27663.1 - 0.00057 19.3 0.1 0.0016 17.8 0.0 1.6 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EER27663.1 - 0.0036 16.7 0.3 0.0081 15.5 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EER27663.1 - 0.021 14.5 0.2 0.057 13.0 0.2 1.7 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EER27663.1 - 0.04 12.7 0.0 0.04 12.7 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EER27663.1 - 0.049 12.6 0.0 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain NUDIX-like PF09296.11 EER27664.1 - 1.9e-16 60.5 0.0 5.5e-16 59.1 0.0 1.8 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 EER27664.1 - 8.9e-16 58.1 0.2 1.9e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EER27664.1 - 5.9e-07 29.0 1.3 1.1e-06 28.1 1.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain TrkA_N PF02254.18 EER27664.1 - 0.14 12.4 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Dynamin_N PF00350.23 EER27666.1 - 1.3e-15 57.8 0.0 2.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EER27666.1 - 7.2e-15 54.9 0.2 2.1e-14 53.4 0.2 1.7 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EER27666.1 - 0.0018 18.4 0.0 0.0053 16.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EER27666.1 - 0.0018 18.8 0.5 0.0096 16.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EER27666.1 - 0.0062 17.1 0.0 0.03 14.8 0.0 2.1 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.9 EER27666.1 - 0.13 12.0 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3340 PF11818.8 EER27666.1 - 0.22 11.7 0.0 0.22 11.7 0.0 2.2 3 0 0 3 3 3 0 C-terminal domain of tail specific protease (DUF3340) Prp18 PF02840.15 EER27667.1 - 3e-55 186.2 0.0 3e-55 186.2 0.0 2.0 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 EER27667.1 - 2.4e-13 49.4 2.0 2.4e-13 49.4 2.0 3.4 4 1 0 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like ERCC3_RAD25_C PF16203.5 EER27668.1 - 2.8e-123 409.9 0.9 4.7e-123 409.2 0.9 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EER27668.1 - 5.2e-34 117.1 0.0 1.4e-33 115.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER27668.1 - 2.5e-16 60.2 0.0 4.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EER27668.1 - 6.8e-14 52.2 0.1 1.6e-13 50.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EER27668.1 - 1.5e-08 33.7 0.0 2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EER27668.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4677 PF15726.5 EER27668.1 - 0.0006 20.0 0.8 0.0014 18.8 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4677) AAA_34 PF13872.6 EER27668.1 - 0.00085 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF4748 PF15932.5 EER27669.1 - 3.5e-22 77.9 1.0 3.5e-22 77.9 1.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4748) DUF676 PF05057.14 EER27671.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EER27671.1 - 0.00015 21.6 0.1 0.00048 19.9 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EER27671.1 - 0.0032 18.1 0.0 0.0043 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF829 PF05705.14 EER27671.1 - 0.094 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Abhydrolase_2 PF02230.16 EER27671.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase CTD_bind PF04818.13 EER27672.1 - 4.4e-11 43.4 0.0 1e-10 42.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. BUD22 PF09073.10 EER27672.1 - 0.3 10.4 11.4 0.51 9.6 11.4 1.4 1 0 0 1 1 1 0 BUD22 EMP24_GP25L PF01105.24 EER27673.1 - 4.1e-45 154.0 0.2 4.7e-45 153.8 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IrmA PF18673.1 EER27673.1 - 0.076 13.1 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 interleukin receptor mimic protein A USP7_ICP0_bdg PF12436.8 EER27674.1 - 5.2e-84 281.3 0.1 2.4e-82 275.9 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EER27674.1 - 1.9e-72 243.3 6.2 2.8e-72 242.7 2.2 3.1 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EER27674.1 - 3.2e-49 167.7 0.4 5.1e-49 167.1 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER27674.1 - 9.2e-20 71.5 0.0 2.4e-19 70.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EER27674.1 - 1.9e-07 31.2 0.0 6.3e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 MATH domain ubiquitin PF00240.23 EER27674.1 - 0.0079 15.9 0.5 36 4.2 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin family Rad60-SLD PF11976.8 EER27674.1 - 0.11 12.4 2.3 33 4.4 0.0 4.1 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like BCDHK_Adom3 PF10436.9 EER27675.1 - 5.5e-47 159.6 1.1 1.6e-46 158.1 0.4 1.9 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EER27675.1 - 2.1e-06 28.2 0.0 9.1e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPC22 PF04573.12 EER27677.1 - 3.7e-35 120.9 0.2 2.1e-25 89.2 0.1 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Peptidase_C48 PF02902.19 EER27678.1 - 7.6e-33 114.2 0.5 9e-32 110.7 0.5 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.18 EER27679.1 - 3.7e-56 189.3 0.1 5.9e-56 188.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Aminotran_1_2 PF00155.21 EER27680.1 - 1.6e-22 80.2 0.0 1.9e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II POT1 PF02765.17 EER27681.1 - 2.3e-18 66.4 0.0 3.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.19 EER27682.1 - 7.2e-44 150.1 0.0 3.8e-24 85.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EER27682.1 - 6.3e-10 38.8 0.0 9.5e-07 28.4 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER27682.1 - 1.4e-09 37.6 0.0 3.3e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER27682.1 - 8.5e-08 32.3 0.0 2.3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EER27682.1 - 1.5e-05 24.3 0.2 0.00021 20.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EER27682.1 - 2.6e-05 24.3 0.2 0.00049 20.1 0.3 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EER27682.1 - 4.5e-05 23.2 0.2 0.091 12.3 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EER27682.1 - 9.9e-05 21.7 0.0 0.00083 18.7 0.0 2.2 3 0 0 3 3 3 1 Thi4 family Amino_oxidase PF01593.24 EER27682.1 - 0.032 13.5 0.0 0.075 12.3 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase MCRA PF06100.11 EER27682.1 - 0.071 11.9 0.1 0.33 9.7 0.0 1.8 2 0 0 2 2 2 0 MCRA family FAD_binding_2 PF00890.24 EER27682.1 - 0.09 11.8 2.8 3.7 6.5 2.0 2.2 1 1 0 2 2 2 0 FAD binding domain HDA2-3 PF11496.8 EER27683.1 - 3.4e-33 115.1 0.3 2.7e-18 66.2 0.0 2.9 2 2 1 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 Cas_DxTHG PF09455.10 EER27683.1 - 0.13 11.8 11.4 0.26 10.9 11.4 1.5 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family CENP-F_leu_zip PF10473.9 EER27683.1 - 1 9.4 46.5 43 4.1 24.3 4.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EER27683.1 - 3.1 7.1 37.4 7.5 5.9 6.7 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4407 PF14362.6 EER27683.1 - 6.4 6.0 33.4 0.044 13.1 18.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Filament PF00038.21 EER27683.1 - 6.6 6.2 40.9 1.3e+02 2.0 40.9 2.4 1 1 0 1 1 1 0 Intermediate filament protein FPP PF05911.11 EER27683.1 - 7.5 4.6 42.6 0.0063 14.8 14.9 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil MIP PF00230.20 EER27684.1 - 2e-34 119.3 18.1 2.5e-34 119.0 18.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein IF-2B PF01008.17 EER27685.1 - 4e-21 75.5 0.0 7.3e-21 74.6 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Transglut_core PF01841.19 EER27686.1 - 2.7e-09 37.5 0.2 6.8e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EER27686.1 - 3.6e-08 33.0 0.2 1.1e-07 31.4 0.2 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EER27686.1 - 1.9e-07 30.6 1.7 2.9e-06 26.8 0.1 2.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EER27686.1 - 0.003 17.4 2.9 0.0083 16.0 0.1 3.1 4 0 0 4 4 4 1 Variant SH3 domain Transglut_core2 PF13369.6 EER27686.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily DHHA2 PF02833.14 EER27687.1 - 1.1e-32 113.2 0.0 2e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EER27687.1 - 1.8e-05 24.9 0.0 5.2e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 DHH family PLU-1 PF08429.11 EER27688.1 - 6.5e-113 377.3 14.3 2.7e-110 368.7 14.0 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EER27688.1 - 2.5e-44 150.3 0.3 6.8e-44 148.9 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EER27688.1 - 7.6e-22 77.8 0.1 1.9e-21 76.5 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EER27688.1 - 3e-18 65.5 4.6 7e-18 64.3 4.6 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EER27688.1 - 3.2e-18 65.4 27.7 4e-10 39.4 6.5 3.5 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 EER27688.1 - 1.9e-11 44.2 10.0 5.5e-11 42.7 10.0 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.6 EER27688.1 - 0.0048 16.5 9.7 0.02 14.5 0.9 2.9 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 EER27688.1 - 1.8 8.7 20.8 0.27 11.4 4.3 3.1 3 0 0 3 3 3 0 PHD-finger GIY-YIG PF01541.24 EER27689.1 - 4.7e-12 46.0 0.0 9e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EER27689.1 - 0.00011 22.3 5.8 0.00022 21.3 5.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-4CXXC_R1 PF10497.9 EER27689.1 - 0.15 12.3 2.2 0.27 11.5 2.2 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD PF00628.29 EER27689.1 - 0.73 9.8 7.2 1.5 8.8 6.1 2.0 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 EER27689.1 - 1 9.3 8.8 0.44 10.5 4.8 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Thymidylate_kin PF02223.17 EER27690.1 - 1.8e-44 151.6 0.0 2.1e-44 151.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EER27690.1 - 0.018 14.5 0.2 0.04 13.4 0.0 1.7 2 1 0 2 2 2 0 Chromatin associated protein KTI12 TGT PF01702.18 EER27691.1 - 1.4e-61 208.6 0.0 1e-53 182.7 0.0 2.0 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase MFS_1 PF07690.16 EER27692.1 - 2.8e-32 112.0 23.7 2.8e-32 112.0 23.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PEP_mutase PF13714.6 EER27693.1 - 4e-53 180.3 0.0 4.8e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EER27693.1 - 1e-10 40.8 0.1 1.5e-10 40.2 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.15 EER27693.1 - 0.0011 18.4 0.0 0.019 14.4 0.0 2.0 1 1 1 2 2 2 1 Ketopantoate hydroxymethyltransferase MTHFR PF02219.17 EER27694.1 - 1.9e-99 332.6 0.0 3e-99 332.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase NDK PF00334.19 EER27695.1 - 3e-54 182.7 0.0 3.5e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 EER27696.1 - 7.9e-140 466.9 7.9 1e-139 466.5 7.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EER27696.1 - 4.5e-25 87.7 0.4 2.1e-24 85.6 0.1 2.3 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EER27696.1 - 3.7e-05 23.9 0.1 0.00014 22.1 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) PQ-loop PF04193.14 EER27697.1 - 4.8e-13 48.7 0.4 4.8e-13 48.7 0.4 2.6 3 0 0 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 EER27697.1 - 0.012 16.5 0.3 0.017 16.0 0.3 1.4 1 1 0 1 1 1 0 ER lumen protein retaining receptor NMT1 PF09084.11 EER27698.1 - 0.0039 17.2 0.0 0.036 14.0 0.0 2.2 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_3 PF16868.5 EER27698.1 - 0.0099 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family NMT1_2 PF13379.6 EER27698.1 - 0.041 13.6 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.20 EER27698.1 - 0.11 11.9 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Glyco_hydro_16 PF00722.21 EER27699.1 - 4.7e-07 29.5 0.0 4.7e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ribosomal_L1 PF00687.21 EER27701.1 - 8.2e-30 104.1 0.1 1.8e-29 103.0 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family COG2 PF06148.11 EER27702.1 - 1.9e-31 108.9 1.7 2.3e-31 108.6 0.5 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EER27702.1 - 6e-07 29.4 0.5 4.2e-06 26.7 0.2 2.5 1 1 1 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.14 EER27702.1 - 0.025 14.5 0.3 0.094 12.6 0.2 1.9 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Bul1_C PF04426.12 EER27702.1 - 0.068 12.6 0.4 0.68 9.3 0.0 2.1 1 1 1 2 2 2 0 Bul1 C terminus ParA PF10609.9 EER27704.1 - 5.5e-85 284.7 0.0 2.9e-57 193.9 0.0 2.1 1 1 1 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EER27704.1 - 2.8e-08 33.9 0.0 9.1e-08 32.2 0.0 1.8 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EER27704.1 - 1.4e-05 24.5 0.0 0.00014 21.3 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EER27704.1 - 8.4e-05 22.5 0.2 0.0034 17.3 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EER27704.1 - 0.0011 18.6 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EER27704.1 - 0.002 17.4 0.9 0.0038 16.4 0.5 1.6 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 EER27704.1 - 0.018 14.0 0.4 0.028 13.4 0.4 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 EER27704.1 - 0.054 13.4 0.1 0.083 12.8 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.6 EER27704.1 - 0.076 12.8 0.4 7.2 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EER27704.1 - 0.12 12.2 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop IstB_IS21 PF01695.17 EER27704.1 - 0.12 12.0 0.0 0.7 9.6 0.1 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein CBP_BcsQ PF06564.12 EER27704.1 - 0.13 11.7 0.6 1 8.8 0.3 2.1 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ Desulfoferrod_N PF06397.12 EER27704.1 - 0.83 9.3 5.3 0.13 11.9 0.8 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain SEP PF08059.13 EER27705.1 - 1.4e-23 83.2 0.1 3.3e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EER27705.1 - 3.6e-15 55.9 0.0 6.1e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EER27705.1 - 7e-13 48.2 0.0 1.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EER27705.1 - 0.0023 17.5 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 TAP C-terminal domain Bcl-2_BAD PF10514.9 EER27705.1 - 1.5 9.3 5.7 0.16 12.4 1.3 1.7 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD TOM13 PF08219.11 EER27706.1 - 5.8e-36 122.3 0.0 8.6e-36 121.8 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Secretin_N PF03958.17 EER27706.1 - 0.028 14.8 0.0 0.042 14.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain 60KD_IMP PF02096.20 EER27707.1 - 7e-21 74.8 0.7 7e-21 74.8 0.7 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein TAFII28 PF04719.14 EER27708.1 - 1.2e-28 99.1 0.5 1e-25 89.6 0.1 2.3 2 0 0 2 2 2 2 hTAFII28-like protein conserved region Nre_N PF04894.12 EER27708.1 - 0.077 12.8 0.1 0.14 12.0 0.1 1.5 1 1 0 1 1 1 0 Archaeal Nre, N-terminal SAM_decarbox PF01536.16 EER27709.1 - 2.8e-133 444.3 0.0 3.3e-133 444.1 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAF6_C PF07571.13 EER27710.1 - 4.7e-29 100.6 0.0 1.5e-28 99.0 0.0 1.9 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EER27710.1 - 8.1e-24 83.6 0.0 1.5e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EER27710.1 - 0.0018 18.3 0.1 0.0046 17.0 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EER27710.1 - 0.035 14.5 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EER27710.1 - 0.12 12.4 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated CRAL_TRIO PF00650.20 EER27711.1 - 4.3e-15 55.8 0.1 9.7e-15 54.6 0.1 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EER27711.1 - 3.2e-09 36.8 0.0 6e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain HemY_N PF07219.13 EER27711.1 - 4.7 7.5 4.7 23 5.3 0.3 2.3 2 0 0 2 2 2 0 HemY protein N-terminus IPP-2 PF04979.14 EER27712.1 - 2.2e-18 67.3 15.0 2.2e-18 67.3 15.0 2.4 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) CAF1A PF12253.8 EER27714.1 - 2.8e-23 81.9 6.8 2.8e-23 81.9 6.8 3.7 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 EER27714.1 - 0.024 14.3 67.8 0.06 13.1 67.8 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF936 PF06075.12 EER27714.1 - 1 8.2 29.7 1.7 7.5 29.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Hid1 PF12722.7 EER27714.1 - 1.1 7.2 18.7 1.7 6.7 18.0 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Peptidase_S64 PF08192.11 EER27714.1 - 6.3 5.2 17.9 9.3 4.6 17.9 1.2 1 0 0 1 1 1 0 Peptidase family S64 Mcm10 PF09332.11 EER27715.1 - 8.2 5.7 8.1 1.9 7.8 3.0 2.0 2 0 0 2 2 2 0 Mcm10 replication factor FAM27 PF15832.5 EER27715.1 - 8.7 7.0 12.0 1.4 9.5 0.7 3.9 3 1 1 4 4 4 0 FAM27 D and E protein family SGL PF08450.12 EER27716.1 - 0.00041 20.0 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 EER27716.1 - 0.003 16.9 0.0 0.063 12.5 0.0 2.4 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.12 EER27716.1 - 0.013 15.5 0.1 0.11 12.4 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat GSDH PF07995.11 EER27716.1 - 0.035 13.4 2.0 3.3 6.9 2.3 3.2 2 1 1 3 3 3 0 Glucose / Sorbosone dehydrogenase PQQ_3 PF13570.6 EER27716.1 - 0.037 14.5 0.3 4.8 7.8 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Lipoprotein_15 PF03640.15 EER27716.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Secreted repeat of unknown function NHL PF01436.21 EER27716.1 - 0.085 12.9 0.0 45 4.4 0.0 3.8 3 0 0 3 3 3 0 NHL repeat CoA_transf_3 PF02515.17 EER27717.1 - 1.3e-66 225.2 0.0 1.6e-66 224.9 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Peptidase_S28 PF05577.12 EER27718.1 - 8.5e-50 169.8 0.3 2.2e-49 168.5 0.3 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 PKcGMP_CC PF16808.5 EER27719.1 - 0.0013 18.5 0.9 0.0013 18.5 0.9 5.3 6 0 0 6 6 6 2 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4472 PF14739.6 EER27719.1 - 0.0095 16.7 5.6 0.0095 16.7 5.6 5.7 4 1 1 5 5 5 1 Domain of unknown function (DUF4472) Filament PF00038.21 EER27719.1 - 0.078 12.5 67.2 0.5 9.9 17.8 4.3 2 2 2 4 4 4 0 Intermediate filament protein Spc7 PF08317.11 EER27719.1 - 1.1 8.0 75.9 1.9 7.3 8.3 4.3 3 1 1 4 4 4 0 Spc7 kinetochore protein E2F_TDP PF02319.20 EER27719.1 - 2.4 8.3 6.4 0.96 9.5 0.4 3.0 3 0 0 3 3 3 0 E2F/DP family winged-helix DNA-binding domain PE PF00934.20 EER27719.1 - 4.6 7.6 9.3 11 6.4 0.4 4.9 5 0 0 5 5 5 0 PE family adh_short_C2 PF13561.6 EER27720.1 - 3e-57 193.9 0.2 3.8e-57 193.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER27720.1 - 7.5e-44 149.5 0.4 1e-43 149.1 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER27720.1 - 9.9e-13 48.4 0.5 1.4e-12 47.9 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EER27720.1 - 0.0015 18.0 0.2 0.0028 17.2 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EER27720.1 - 0.0024 17.3 0.1 0.0033 16.9 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EER27720.1 - 0.0077 15.3 0.6 0.018 14.1 0.1 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 EER27720.1 - 0.043 14.0 0.4 0.25 11.5 0.1 2.2 2 1 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_18 PF00704.28 EER27721.1 - 3.7e-16 59.7 0.0 4.6e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.10 EER27722.1 - 1.4e-38 132.9 0.0 3.3e-38 131.6 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 EER27722.1 - 0.0042 17.6 0.1 0.0089 16.6 0.1 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EER27722.1 - 0.091 13.3 0.0 0.22 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain eIF_4G1 PF12152.8 EER27722.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4G1 SRP54 PF00448.22 EER27723.1 - 1.5e-73 246.6 2.3 2.7e-73 245.8 2.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EER27723.1 - 3.1e-29 101.5 0.0 3.1e-29 101.5 0.0 4.2 3 1 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.19 EER27723.1 - 1.3e-19 70.2 0.4 3.4e-19 68.8 0.4 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EER27723.1 - 2.4e-06 27.2 0.4 8.2e-06 25.5 0.4 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 EER27723.1 - 6e-06 26.7 1.7 8.2e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EER27723.1 - 1.3e-05 25.4 0.1 3.4e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EER27723.1 - 1.7e-05 25.3 0.0 3.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 EER27723.1 - 0.00013 21.0 1.1 0.00082 18.4 0.1 2.6 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EER27723.1 - 0.0012 18.7 0.3 0.0043 16.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EER27723.1 - 0.0016 18.7 0.1 0.0089 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EER27723.1 - 0.0018 17.6 0.1 0.0043 16.4 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin SRPRB PF09439.10 EER27723.1 - 0.0019 17.6 1.2 1.1 8.7 1.3 2.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit APS_kinase PF01583.20 EER27723.1 - 0.0019 18.1 0.0 0.0048 16.8 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase ResIII PF04851.15 EER27723.1 - 0.003 17.6 0.5 0.01 15.9 0.5 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.17 EER27723.1 - 0.0035 17.2 0.7 0.014 15.2 0.1 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 EER27723.1 - 0.0047 17.0 0.0 0.015 15.3 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 EER27723.1 - 0.0061 17.1 0.0 0.017 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EER27723.1 - 0.0066 16.2 0.2 0.033 13.9 0.1 2.3 3 0 0 3 3 3 1 Thymidylate kinase MMR_HSR1 PF01926.23 EER27723.1 - 0.0072 16.4 0.2 0.035 14.2 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EER27723.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.6 EER27723.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EER27723.1 - 0.022 14.5 0.1 0.05 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EER27723.1 - 0.025 14.5 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 EER27723.1 - 0.039 14.3 0.1 0.1 13.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain DUF1631 PF07793.11 EER27723.1 - 0.057 11.8 1.6 1.9 6.8 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) HAUS2 PF15003.6 EER27723.1 - 0.087 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 AAA_7 PF12775.7 EER27723.1 - 0.11 12.0 0.4 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region Arf PF00025.21 EER27723.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family ABC_tran PF00005.27 EER27723.1 - 0.16 12.5 0.7 0.44 11.1 0.1 2.1 2 1 0 2 2 2 0 ABC transporter Rrp15p PF07890.12 EER27724.1 - 3.7e-39 134.1 13.0 3.7e-39 134.1 13.0 1.8 3 0 0 3 3 3 1 Rrp15p DUF2799 PF10973.8 EER27724.1 - 0.3 11.6 1.3 8.7 6.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2799) MEKHLA PF08670.11 EER27724.1 - 0.49 10.3 3.0 23 4.9 0.2 2.9 1 1 2 3 3 3 0 MEKHLA domain Fer2 PF00111.27 EER27725.1 - 1.4e-12 47.3 0.9 2.1e-12 46.8 0.9 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Ig_2 PF13895.6 EER27725.1 - 0.066 13.6 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Immunoglobulin domain Mito_carr PF00153.27 EER27726.1 - 2.6e-09 36.9 1.9 0.0009 19.1 0.0 4.5 4 1 0 4 4 4 3 Mitochondrial carrier protein Hap4_Hap_bind PF10297.9 EER27727.1 - 3.3e-08 33.4 6.1 3.3e-08 33.4 6.1 2.3 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EER27727.1 - 3.3e-07 30.3 12.5 6.6e-07 29.3 12.1 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EER27727.1 - 0.00016 21.7 6.8 0.00039 20.4 6.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper ADIP PF11559.8 EER27727.1 - 0.023 14.8 3.6 0.038 14.1 3.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CDC45 PF02724.14 EER27727.1 - 0.098 10.9 0.3 0.13 10.6 0.3 1.2 1 0 0 1 1 1 0 CDC45-like protein dsrm PF00035.26 EER27727.1 - 0.12 13.1 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF4407 PF14362.6 EER27727.1 - 0.85 8.9 5.1 1.2 8.5 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cauli_AT PF03233.13 EER27727.1 - 1.2 9.0 4.6 1.1 9.1 2.4 1.8 1 1 1 2 2 2 0 Aphid transmission protein Pil1 PF13805.6 EER27727.1 - 2.1 7.8 7.0 0.43 10.0 0.1 2.1 1 1 1 2 2 2 0 Eisosome component PIL1 V_ATPase_I PF01496.19 EER27727.1 - 3.5 5.4 4.0 4.2 5.2 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 EER27727.1 - 3.7 8.1 10.1 0.64 10.6 6.1 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF5320 PF17253.2 EER27727.1 - 3.9 8.6 7.6 0.81 10.8 0.8 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Methyltransf_24 PF13578.6 EER27728.1 - 4.4e-13 50.2 0.0 6.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EER27728.1 - 1.2e-05 24.6 0.0 8.6e-05 21.8 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 EER27728.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase DUF2089 PF09862.9 EER27728.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) Ribosomal_L19 PF01245.20 EER27729.1 - 6.3e-13 48.6 0.2 1.2e-12 47.8 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 AMP-binding PF00501.28 EER27731.1 - 1.8e-15 56.5 0.0 8.6e-15 54.2 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NPCC PF08058.11 EER27732.1 - 5.1e-26 91.2 0.0 6.8e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.9 EER27732.1 - 0.0065 15.5 0.0 0.0078 15.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Hid1 PF12722.7 EER27733.1 - 0 1079.5 0.0 0 1079.3 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EER27733.1 - 7e-101 338.6 0.0 8.4e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Cupin_2 PF07883.11 EER27735.1 - 7.5e-06 25.6 0.1 1.2e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 EER27735.1 - 0.053 13.4 0.0 0.071 13.0 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase HAT_KAT11 PF08214.11 EER27736.1 - 6.7e-93 311.8 0.0 9.4e-93 311.3 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Glyco_transf_21 PF13506.6 EER27737.1 - 1.8e-11 43.8 0.0 1.4e-05 24.6 0.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EER27737.1 - 8.3e-10 38.9 0.0 2.8e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EER27737.1 - 0.00058 19.7 0.0 0.0023 17.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.7 EER27738.1 - 2.5e-15 56.8 0.2 8.9e-15 55.1 0.2 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER27738.1 - 2.7e-15 56.5 0.6 2.1e-09 37.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER27738.1 - 2.9e-12 45.6 0.6 2.9e-07 30.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EER27738.1 - 1.6e-11 44.1 1.3 1.2e-07 31.9 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EER27738.1 - 2.8e-10 40.2 2.5 1.6e-08 34.7 0.5 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) WW PF00397.26 EER27739.1 - 5.3e-10 39.2 1.1 1.6e-09 37.7 1.1 1.8 1 0 0 1 1 1 1 WW domain WRW PF10206.9 EER27739.1 - 0.045 14.1 0.2 0.12 12.8 0.2 1.6 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f FAD_binding_2 PF00890.24 EER27740.1 - 1.1e-120 403.6 1.7 1.3e-120 403.3 1.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EER27740.1 - 7.8e-41 139.1 0.4 1.2e-40 138.5 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EER27740.1 - 0.00019 20.6 2.1 0.015 14.4 2.7 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EER27740.1 - 0.00021 20.7 0.5 0.00042 19.7 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EER27740.1 - 0.00027 19.7 1.8 0.002 16.9 0.9 2.7 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_2 PF07992.14 EER27740.1 - 0.0026 17.0 1.0 0.0054 16.0 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER27740.1 - 0.0065 15.7 0.2 0.15 11.3 0.1 2.4 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EER27740.1 - 0.0074 15.9 0.5 0.015 14.9 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EER27740.1 - 2.3 7.4 3.6 3.6 6.8 2.8 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hydrophobin PF01185.18 EER27741.1 - 2.2e-11 44.2 10.4 2.7e-11 43.9 10.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Alpha_GJ PF03229.13 EER27741.1 - 0.3 11.7 5.3 0.68 10.5 5.3 1.6 1 1 0 1 1 1 0 Alphavirus glycoprotein J NMO PF03060.15 EER27742.1 - 2.9e-58 197.8 0.1 3.2e-57 194.4 0.1 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EER27742.1 - 6.5e-15 55.0 0.0 1.5e-13 50.5 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EER27742.1 - 0.00033 19.8 1.0 0.00098 18.2 0.6 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.14 EER27742.1 - 0.011 15.0 0.1 0.037 13.2 0.1 2.0 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.17 EER27742.1 - 0.092 11.9 1.7 0.32 10.1 1.7 2.0 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.11 EER27742.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Sdh_cyt PF01127.22 EER27743.1 - 5.2e-24 84.6 3.0 7.2e-24 84.1 3.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribonucleas_3_3 PF14622.6 EER27744.1 - 3.1e-27 95.3 0.0 5.8e-27 94.4 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EER27744.1 - 0.00064 20.3 0.1 0.0025 18.4 0.1 2.0 1 1 0 1 1 1 1 Ribonuclease III domain DUF2559 PF10832.8 EER27744.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2559) Adap_comp_sub PF00928.21 EER27745.1 - 4.6e-92 308.1 0.0 9e-92 307.2 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EER27745.1 - 1.5e-09 37.9 0.2 2.4e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EER27745.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain ABC2_membrane PF01061.24 EER27747.1 - 2.2e-78 262.5 50.2 2.5e-41 141.4 16.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EER27747.1 - 1.1e-35 123.2 0.0 1.1e-18 68.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EER27747.1 - 2.8e-24 84.8 2.3 2.6e-20 72.1 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EER27747.1 - 1.4e-13 51.3 0.0 1.6e-12 47.8 0.0 2.7 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EER27747.1 - 1.8e-13 50.3 27.3 1.5e-10 40.7 7.0 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EER27747.1 - 8.5e-07 29.1 0.3 0.012 15.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EER27747.1 - 0.00012 22.5 2.2 0.0076 16.7 0.0 3.4 4 0 0 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 EER27747.1 - 0.0012 19.3 0.2 0.014 16.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.6 EER27747.1 - 0.0018 18.4 0.1 0.019 15.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EER27747.1 - 0.0024 17.8 0.0 0.0061 16.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EER27747.1 - 0.0026 17.5 0.2 0.011 15.5 0.1 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EER27747.1 - 0.0041 17.4 0.2 0.099 12.9 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EER27747.1 - 0.0057 16.3 1.8 0.014 15.0 0.1 2.5 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 EER27747.1 - 0.012 15.1 0.0 0.74 9.2 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 EER27747.1 - 0.032 13.8 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EER27747.1 - 0.098 12.9 0.1 0.37 11.1 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EER27747.1 - 0.1 13.0 1.2 0.21 12.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.6 EER27747.1 - 0.28 11.7 0.1 0.28 11.7 0.1 3.7 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EER27748.1 - 2.1e-48 164.3 0.1 2.2e-25 89.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EER27748.1 - 1.9e-26 93.0 44.1 4.5e-18 65.5 23.7 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 EER27748.1 - 5.5e-22 79.0 4.4 4e-05 23.6 1.0 4.7 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EER27748.1 - 3.5e-09 36.3 1.8 6.6e-05 22.6 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EER27748.1 - 1.9e-08 34.0 2.7 0.02 14.3 0.0 3.7 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EER27748.1 - 4.2e-08 33.9 1.4 0.0076 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 EER27748.1 - 8.4e-06 25.5 0.4 0.12 12.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EER27748.1 - 6.6e-05 22.9 0.3 0.4 10.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EER27748.1 - 0.0002 21.2 0.0 0.023 14.4 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 EER27748.1 - 0.00032 21.1 0.2 0.76 10.1 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF4162 PF13732.6 EER27748.1 - 0.0019 18.9 0.0 0.023 15.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_30 PF13604.6 EER27748.1 - 0.002 17.9 3.0 1.4 8.6 0.2 3.0 2 1 1 3 3 3 2 AAA domain ABC2_membrane PF01061.24 EER27748.1 - 0.0038 16.7 19.6 0.0038 16.7 19.6 3.7 3 1 0 3 3 3 1 ABC-2 type transporter AAA_28 PF13521.6 EER27748.1 - 0.028 14.7 0.4 5 7.4 0.3 2.4 2 0 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 EER27748.1 - 0.069 12.7 0.1 7.5 6.0 0.0 3.0 3 0 0 3 3 3 0 P-loop Nucleotide Kinase1 AAA_18 PF13238.6 EER27748.1 - 0.069 13.7 0.0 13 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EER27748.1 - 0.077 13.3 0.2 9.7 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EER27748.1 - 0.082 13.1 2.1 14 6.0 0.2 4.0 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 EER27748.1 - 0.084 12.5 0.7 13 5.4 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MukB PF04310.12 EER27748.1 - 0.13 12.0 0.2 23 4.7 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal Rad17 PF03215.15 EER27748.1 - 0.17 11.8 0.0 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EER27748.1 - 0.18 11.1 0.4 19 4.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EER27748.1 - 0.74 9.3 2.5 21 4.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 EER27750.1 - 1.8e-35 122.5 51.9 1.8e-35 122.5 51.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER27750.1 - 1.9e-14 53.4 9.3 1.9e-14 53.4 9.3 2.9 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EER27750.1 - 1.1e-13 50.5 21.1 1.6e-13 49.9 21.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HDPD PF02924.14 EER27750.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D UBM PF14377.6 EER27750.1 - 0.017 14.6 0.2 0.038 13.5 0.2 1.6 1 0 0 1 1 1 0 Ubiquitin binding region DUF1100 PF06500.11 EER27751.1 - 1.7e-12 46.9 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 EER27751.1 - 3.8e-08 34.2 0.2 7.8e-08 33.2 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER27751.1 - 0.0012 18.1 0.0 0.0024 17.2 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EER27751.1 - 0.0041 16.6 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family AMP-binding PF00501.28 EER27752.1 - 1.8e-75 254.2 0.0 7.3e-75 252.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EER27752.1 - 1.7e-73 247.3 0.0 4.1e-73 246.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EER27752.1 - 1.7e-62 211.6 0.8 2.5e-62 211.1 0.8 1.2 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EER27752.1 - 6.7e-49 166.7 0.0 1.1e-48 166.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EER27752.1 - 5.3e-47 160.1 0.0 4.3e-45 153.8 0.0 3.1 2 1 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.21 EER27752.1 - 1.4e-40 139.8 0.0 2.4e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EER27752.1 - 3.7e-35 121.3 0.0 4.5e-34 117.8 0.0 2.5 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EER27752.1 - 3.2e-30 104.6 0.1 6.6e-30 103.6 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EER27752.1 - 3e-18 66.4 0.0 9.4e-18 64.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EER27752.1 - 1.1e-16 60.9 5.6 1.5e-09 38.0 0.2 3.2 2 0 0 2 2 2 2 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EER27752.1 - 1e-13 51.7 0.0 2.4e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EER27752.1 - 6.6e-12 45.4 0.0 6.3e-11 42.2 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EER27752.1 - 6.8e-12 45.5 0.0 1.6e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER27752.1 - 1.2e-11 45.1 0.0 4.6e-11 43.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER27752.1 - 9.5e-11 42.2 0.0 2.7e-10 40.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER27752.1 - 8.3e-10 38.7 0.0 2.7e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 EER27752.1 - 5.3e-06 25.6 0.0 1.2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 EER27752.1 - 1.1e-05 24.9 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 EER27752.1 - 1.3e-05 24.8 0.0 0.00072 19.1 0.0 3.3 3 1 0 3 3 3 1 short chain dehydrogenase Ubie_methyltran PF01209.18 EER27752.1 - 0.00017 21.0 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EER27752.1 - 0.00056 19.7 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase adh_short_C2 PF13561.6 EER27752.1 - 0.0072 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EER27752.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding ADH_zinc_N PF00107.26 EER27754.1 - 4e-09 36.5 0.0 6.8e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER27754.1 - 0.0042 17.0 0.0 0.0099 15.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EER27754.1 - 0.027 15.5 0.0 0.043 14.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Zn_clus PF00172.18 EER27755.1 - 0.00083 19.4 8.3 0.0015 18.6 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M18 PF02127.15 EER27756.1 - 1.5e-133 445.8 0.0 1.7e-133 445.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) NOB1_Zn_bind PF08772.11 EER27757.1 - 3e-32 110.6 3.3 5.3e-32 109.8 3.3 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EER27757.1 - 1.1e-29 102.7 0.0 2.4e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 PIN domain of ribonuclease HypA PF01155.19 EER27757.1 - 0.0011 19.0 0.2 0.21 11.6 0.5 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 EER27757.1 - 0.0024 17.5 1.4 0.0081 15.8 1.4 1.9 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain SDA1 PF05285.12 EER27757.1 - 0.049 13.1 1.6 0.06 12.8 1.6 1.2 1 0 0 1 1 1 0 SDA1 WRNPLPNID PF15017.6 EER27757.1 - 0.21 12.5 7.9 0.19 12.6 3.0 2.6 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Zn-ribbon_8 PF09723.10 EER27757.1 - 0.53 10.4 3.6 0.41 10.8 1.5 1.9 2 0 0 2 2 2 0 Zinc ribbon domain Nudix_N_2 PF14803.6 EER27757.1 - 1.4 8.9 4.6 2.1 8.3 1.4 2.7 2 0 0 2 2 2 0 Nudix N-terminal Nop10p PF04135.12 EER27758.1 - 2.8e-22 78.5 0.6 3.4e-22 78.2 0.6 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family tRNA_int_endo PF01974.17 EER27759.1 - 7.8e-20 70.7 0.4 2.5e-19 69.1 0.4 1.9 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EER27759.1 - 3.9e-06 26.5 0.0 0.00093 18.8 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain DUF4694 PF15765.5 EER27759.1 - 0.089 12.8 1.9 0.15 12.1 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) S-methyl_trans PF02574.16 EER27760.1 - 3.2e-51 174.7 0.0 3.6e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Tudor_3 PF18115.1 EER27761.1 - 1.3e-19 69.8 0.0 3.8e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Rad9_Rad53_bind PF08605.10 EER27761.1 - 9.6e-14 51.7 0.0 1.6e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT_2 PF16589.5 EER27761.1 - 4.2e-08 33.5 0.0 1.7e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EER27761.1 - 1.1e-06 28.9 0.0 4.1e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EER27761.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain DUF1118 PF06549.12 EER27761.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) Ribosomal_L27 PF01016.19 EER27762.1 - 1.1e-30 105.5 0.1 1.7e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Scramblase PF03803.15 EER27764.1 - 8.4e-51 172.4 0.0 1.6e-26 93.0 0.0 2.2 1 1 1 2 2 2 2 Scramblase UQ_con PF00179.26 EER27765.1 - 1.1e-48 164.4 0.0 1.2e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TP6A_N PF04406.14 EER27766.1 - 2.5e-14 53.0 0.0 4.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SQHop_cyclase_C PF13243.6 EER27767.1 - 3.3e-47 161.2 0.6 1.8e-44 152.2 1.7 2.4 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EER27767.1 - 2.5e-43 148.2 5.5 1.4e-37 129.4 0.2 3.2 3 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EER27767.1 - 9.2e-35 118.1 4.4 2.2e-10 40.1 0.2 5.7 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EER27767.1 - 7.3e-07 28.8 0.5 0.57 9.5 0.1 4.3 2 1 3 5 5 5 3 Pectic acid lyase SGS PF05002.15 EER27768.1 - 1.1e-29 102.3 3.6 3.7e-29 100.6 3.6 2.0 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EER27768.1 - 6.8e-14 52.6 0.1 1.3e-13 51.7 0.1 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 EER27768.1 - 0.001 18.8 0.0 0.087 12.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EER27768.1 - 0.0014 18.5 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EER27768.1 - 0.044 14.3 0.0 5.4 7.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat PQ-loop PF04193.14 EER27769.1 - 2.2e-41 139.4 11.3 1.7e-21 75.7 1.6 2.9 2 0 0 2 2 2 2 PQ loop repeat adh_short PF00106.25 EER27770.1 - 2.3e-46 157.7 0.1 3.1e-46 157.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER27770.1 - 2.7e-34 118.8 0.3 3.5e-34 118.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER27770.1 - 1.3e-11 44.7 0.1 2.2e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EER27770.1 - 6.1e-08 32.4 0.0 7.8e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EER27770.1 - 0.0079 15.7 0.2 0.014 14.8 0.1 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EER27770.1 - 0.021 14.0 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DASH_Duo1 PF08651.10 EER27770.1 - 0.19 11.5 0.0 0.83 9.5 0.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 tRNA-synt_1e PF01406.19 EER27771.1 - 3.2e-117 391.2 0.0 5e-117 390.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EER27771.1 - 1.8e-06 26.9 0.3 0.027 13.2 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EER27771.1 - 0.0074 16.8 0.0 0.026 15.0 0.0 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 EER27771.1 - 0.018 14.0 0.0 2.2 7.1 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) Caleosin PF05042.13 EER27771.1 - 0.077 12.9 0.1 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Caleosin related protein GCD14 PF08704.10 EER27772.1 - 2.1e-62 211.0 0.1 9.2e-61 205.6 0.1 2.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit TPR_2 PF07719.17 EER27773.1 - 1.4e-05 24.8 0.1 0.021 14.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER27773.1 - 6.2e-05 22.6 0.0 0.034 14.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EER27773.1 - 8.1e-05 22.8 0.1 0.0054 17.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.31 EER27773.1 - 0.00019 21.2 0.0 0.0005 19.9 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_11 PF13414.6 EER27773.1 - 0.037 13.7 0.0 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 TPR repeat DnaJ PF00226.31 EER27773.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 DnaJ domain TPR_16 PF13432.6 EER27773.1 - 1.4 9.6 13.8 1.2 9.9 1.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF1688 PF07958.11 EER27774.1 - 4.3e-183 608.8 0.0 4.9e-183 608.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.12 EER27775.1 - 1.1e-92 309.5 0.7 1.4e-92 309.3 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EER27775.1 - 4.9e-09 35.9 0.0 1.5e-08 34.3 0.0 1.7 1 1 1 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 EER27775.1 - 2.8e-08 34.0 0.0 5.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EER27775.1 - 1.8e-07 30.9 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EER27775.1 - 2.5e-07 30.8 0.0 4.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EER27775.1 - 0.0036 17.3 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain G-alpha PF00503.20 EER27775.1 - 0.01 15.0 3.9 1.6 7.8 1.5 2.3 1 1 1 2 2 2 0 G-protein alpha subunit DUF815 PF05673.13 EER27775.1 - 0.011 15.0 0.1 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EER27775.1 - 0.015 15.8 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EER27775.1 - 0.016 14.9 1.0 0.066 13.0 0.5 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EER27775.1 - 0.038 13.9 1.2 0.36 10.7 0.1 2.8 3 1 0 3 3 3 0 RsgA GTPase AIG1 PF04548.16 EER27775.1 - 0.068 12.5 1.6 0.17 11.2 0.4 2.3 2 1 0 2 2 2 0 AIG1 family SRPRB PF09439.10 EER27775.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EER27775.1 - 0.15 11.6 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AA_permease PF00324.21 EER27776.1 - 7.8e-126 420.5 33.7 9.5e-126 420.2 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER27776.1 - 2.3e-35 122.3 33.1 2.9e-35 121.9 33.1 1.2 1 0 0 1 1 1 1 Amino acid permease RdRP PF05183.12 EER27777.1 - 7e-132 441.0 0.0 9.8e-132 440.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase MFS_1 PF07690.16 EER27778.1 - 1.1e-38 133.1 36.9 1.1e-38 133.1 36.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER27778.1 - 6.4e-12 45.1 7.1 6.4e-12 45.1 7.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EER27778.1 - 1e-05 25.1 1.6 1e-05 25.1 1.6 2.4 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Mem_trans PF03547.18 EER27778.1 - 0.041 12.3 0.6 1.5 7.1 0.0 2.3 1 1 1 2 2 2 0 Membrane transport protein Opi1 PF08618.10 EER27779.1 - 9.3e-45 153.6 24.0 6.1e-33 114.7 4.8 3.4 3 1 1 4 4 4 3 Transcription factor Opi1 adh_short_C2 PF13561.6 EER27780.1 - 4.6e-58 196.5 4.2 9.8e-58 195.5 4.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER27780.1 - 3.3e-34 118.1 2.8 2.7e-33 115.1 2.8 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER27780.1 - 1.6e-06 28.2 1.4 1.5e-05 24.9 0.2 2.1 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 EER27780.1 - 0.015 14.6 0.2 0.05 13.0 0.2 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EER27780.1 - 0.039 13.9 0.2 0.72 9.8 0.2 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IceA2 PF05862.11 EER27780.1 - 0.041 13.8 0.5 0.2 11.6 0.1 2.3 3 0 0 3 3 3 0 Helicobacter pylori IceA2 protein 3HCDH_N PF02737.18 EER27780.1 - 0.087 12.7 0.2 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain LIP PF03583.14 EER27781.1 - 5.3e-82 275.4 0.0 7e-82 275.0 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EER27781.1 - 0.11 11.9 0.1 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Voldacs PF03517.13 EER27782.1 - 2.7e-29 102.1 0.1 2.7e-29 102.1 0.1 1.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Metallophos PF00149.28 EER27784.1 - 7.5e-36 124.5 0.1 1.4e-35 123.7 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.11 EER27784.1 - 0.038 13.7 1.0 2.1 8.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1647) Abhydrolase_2 PF02230.16 EER27786.1 - 6.2e-15 55.6 0.0 8.3e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EER27786.1 - 0.0025 18.5 0.3 0.0029 18.2 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EER27786.1 - 0.05 13.3 0.0 0.25 11.0 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) EXS PF03124.14 EER27787.1 - 3.6e-83 279.6 20.3 5.4e-75 252.8 12.2 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.19 EER27787.1 - 1.9e-79 268.4 1.2 1.9e-79 268.4 1.2 1.7 2 0 0 2 2 2 1 SPX domain Peptidase_S8 PF00082.22 EER27788.1 - 2.4e-35 122.2 8.7 4.8e-35 121.3 8.6 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER27788.1 - 1.1e-20 74.1 0.4 2.4e-20 73.0 0.4 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 EER27789.1 - 2.9e-121 404.1 0.0 4.9e-121 403.3 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EER27789.1 - 1.8e-09 37.6 1.8 2.1e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EER27789.1 - 1.3e-08 35.1 0.0 3.1e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 EER27789.1 - 0.00046 20.9 1.0 3 8.8 0.0 3.3 2 0 0 2 2 2 2 WD domain, G-beta repeat TAL_FSA PF00923.19 EER27790.1 - 7.4e-94 314.3 0.3 8.4e-94 314.1 0.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 EER27790.1 - 0.064 12.8 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Pkinase_fungal PF17667.1 EER27791.1 - 3.1e-113 378.6 0.0 2.5e-110 369.1 0.0 2.1 1 1 1 2 2 2 2 Fungal protein kinase Pkinase PF00069.25 EER27791.1 - 4e-07 29.7 0.0 6.7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27791.1 - 0.0071 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EER27791.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EER27791.1 - 0.09 12.7 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sod_Cu PF00080.20 EER27792.1 - 9.7e-47 158.7 6.1 1.2e-46 158.4 6.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF1522 PF07482.11 EER27792.1 - 0.018 15.4 1.5 0.11 12.8 0.4 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1522) SNase PF00565.17 EER27793.1 - 7e-81 267.8 0.4 8.5e-26 90.6 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EER27793.1 - 9e-26 90.3 0.0 3e-25 88.6 0.0 1.8 2 0 0 2 2 2 1 Tudor domain SMN PF06003.12 EER27793.1 - 0.0015 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EER27793.1 - 0.011 16.2 0.2 0.14 12.7 0.1 2.8 3 0 0 3 3 3 0 Agenet domain CRAL_TRIO PF00650.20 EER27794.1 - 1.2e-24 86.9 0.0 1.9e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EER27794.1 - 4.7e-10 39.5 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AT_hook PF02178.19 EER27795.1 - 7.2e-09 34.5 59.1 0.021 14.6 2.6 6.9 6 0 0 6 6 6 6 AT hook motif EMC1_C PF07774.13 EER27796.1 - 8.4e-77 257.6 0.0 2.3e-76 256.2 0.0 1.8 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EER27796.1 - 1.4e-19 70.7 8.5 3.6e-16 59.5 3.8 3.3 2 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 EER27796.1 - 6e-06 25.9 4.0 8.5 6.5 0.1 7.3 8 0 0 8 8 8 1 PQQ enzyme repeat PQQ_3 PF13570.6 EER27796.1 - 0.011 16.2 4.2 28 5.4 0.6 5.8 6 0 0 6 6 6 0 PQQ-like domain Peptidase_M35 PF02102.15 EER27797.1 - 8.9e-98 327.5 4.4 1.1e-97 327.2 4.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EER27797.1 - 8e-45 152.9 1.2 8e-45 152.9 1.2 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Binary_toxB_3 PF17476.2 EER27797.1 - 0.083 13.1 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 DUF1479 PF07350.12 EER27798.1 - 5.9e-167 555.6 0.0 6.9e-167 555.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EER27798.1 - 0.11 12.8 0.0 2.3 8.4 0.0 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.25 EER27799.1 - 1.1e-36 126.1 0.0 1.4e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER27799.1 - 1.4e-31 109.8 0.0 1.9e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER27799.1 - 7.3e-07 29.3 0.0 4.1e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 KR domain Aa_trans PF01490.18 EER27800.1 - 2.8e-92 309.6 17.3 4.5e-92 308.9 17.3 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Bax1-I PF01027.20 EER27801.1 - 7.6e-52 176.2 31.9 8.7e-52 176.0 31.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 7TMR-DISM_7TM PF07695.11 EER27801.1 - 4.7 7.0 34.6 3.4 7.5 16.2 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling UQ_con PF00179.26 EER27803.1 - 3.9e-37 127.0 0.0 4.9e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC_tran PF00005.27 EER27804.1 - 6.3e-54 182.2 0.0 1.4e-30 106.6 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EER27804.1 - 6.6e-50 170.3 28.5 6.1e-31 108.1 9.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EER27804.1 - 6.3e-07 29.0 8.6 0.08 12.4 3.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EER27804.1 - 8.5e-06 26.4 1.7 0.0062 17.0 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EER27804.1 - 0.00022 21.1 0.9 1.6 8.5 0.5 3.3 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EER27804.1 - 0.00038 20.9 0.9 1.3 9.4 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EER27804.1 - 0.00045 20.3 0.2 0.06 13.4 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EER27804.1 - 0.0005 19.8 0.4 0.66 9.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 EER27804.1 - 0.00084 19.5 2.5 0.0041 17.2 0.3 2.6 2 1 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EER27804.1 - 0.0011 19.0 0.7 1.2 9.0 0.0 2.8 3 0 0 3 3 3 2 RsgA GTPase T2SSE PF00437.20 EER27804.1 - 0.0011 18.1 0.0 0.023 13.8 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EER27804.1 - 0.0018 17.2 1.0 0.5 9.2 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 EER27804.1 - 0.0041 17.4 1.8 6.3 7.1 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 EER27804.1 - 0.039 13.5 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EER27804.1 - 0.042 13.6 0.1 3.4 7.3 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 EER27804.1 - 0.048 13.2 0.9 0.82 9.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EER27804.1 - 0.082 12.6 0.2 6.3 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EER27804.1 - 0.083 12.2 0.1 15 4.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EER27804.1 - 0.12 11.9 0.2 12 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EER27804.1 - 0.15 12.5 0.1 31 5.0 0.0 3.2 3 0 0 3 3 2 0 RNA helicase AAA PF00004.29 EER27804.1 - 0.15 12.4 1.6 16 5.9 0.2 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EER27804.1 - 0.16 11.9 0.0 8.1 6.4 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit GCD14 PF08704.10 EER27805.1 - 0.16 11.6 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit AAA_12 PF13087.6 EER27806.1 - 1.7e-32 112.6 0.0 2.8e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EER27806.1 - 3e-23 82.9 0.0 5.1e-12 46.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EER27806.1 - 1.4e-09 38.5 0.0 5.7e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EER27806.1 - 1.5e-09 37.8 0.0 1.3e-06 28.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EER27806.1 - 0.00024 20.9 0.0 0.81 9.4 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EER27806.1 - 0.0059 16.6 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EER27806.1 - 0.009 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.16 EER27806.1 - 0.021 14.3 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.9 EER27806.1 - 0.021 14.1 0.1 1 8.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EER27806.1 - 0.12 11.8 0.0 0.64 9.5 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain WD40 PF00400.32 EER27807.1 - 5.4e-16 58.7 1.5 0.6 11.1 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27807.1 - 0.00098 19.4 0.0 15 6.0 0.0 4.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 EER27807.1 - 0.16 10.8 0.0 0.63 8.9 0.0 1.8 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PRP38 PF03371.15 EER27809.1 - 3.7e-65 219.0 0.0 4.7e-65 218.7 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Tnp_22_trimer PF17489.2 EER27809.1 - 0.074 13.0 1.0 0.16 12.0 1.0 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain DUF3445 PF11927.8 EER27810.1 - 2.1e-75 253.2 0.0 2.7e-75 252.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_90 PF05686.12 EER27811.1 - 5e-13 48.7 0.5 3.9e-12 45.8 0.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 90 Asp PF00026.23 EER27812.1 - 9.2e-05 22.0 0.1 0.00015 21.3 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease WSC PF01822.19 EER27813.1 - 2.3e-08 34.1 6.1 5.3e-08 32.9 6.1 1.6 1 0 0 1 1 1 1 WSC domain DUF4690 PF15756.5 EER27813.1 - 0.0047 17.5 2.2 0.0047 17.5 2.2 1.7 1 1 0 1 1 1 1 Small Novel Rich in Cartilage DUF5305 PF17231.2 EER27813.1 - 0.012 15.0 0.1 0.02 14.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) LapA_dom PF06305.11 EER27813.1 - 0.091 12.6 0.6 0.17 11.7 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain EphA2_TM PF14575.6 EER27813.1 - 0.16 12.9 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EER27813.1 - 0.19 11.6 6.3 1.4 8.9 6.3 2.2 1 1 0 1 1 1 0 TMEM154 protein family Phage_holin_2_4 PF16082.5 EER27813.1 - 0.83 9.4 2.0 0.62 9.8 0.1 1.7 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like MFS_1 PF07690.16 EER27814.1 - 8e-27 94.1 47.0 9.8e-27 93.8 47.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER27814.1 - 0.012 14.5 31.4 0.019 13.8 7.1 2.4 1 1 0 2 2 2 0 Sugar (and other) transporter p450 PF00067.22 EER27816.1 - 5.3e-39 134.2 0.0 1.8e-33 116.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Zn_clus PF00172.18 EER27817.1 - 2.8e-11 43.4 8.5 4.9e-11 42.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EER27817.1 - 4.5e-08 32.5 0.0 8e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1133 PF06576.11 EER27817.1 - 0.00071 19.0 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1133) NAD_binding_6 PF08030.12 EER27817.1 - 0.16 12.1 0.1 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain HNH_2 PF13391.6 EER27819.1 - 2.7e-16 59.5 0.0 5.9e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease IMS PF00817.20 EER27821.1 - 4.1e-36 124.2 0.0 2.8e-20 72.8 0.0 2.3 1 1 0 2 2 2 2 impB/mucB/samB family IMS_C PF11799.8 EER27821.1 - 1.8e-14 54.4 0.0 4.8e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EER27821.1 - 4.3e-14 51.8 0.4 1e-13 50.6 0.4 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 EER27821.1 - 0.024 14.9 0.0 0.052 13.9 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif ABC1 PF03109.16 EER27822.1 - 8.5e-22 77.5 0.3 5e-21 75.1 0.1 2.1 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EER27822.1 - 0.074 13.0 0.2 0.28 11.1 0.2 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family GST_N_3 PF13417.6 EER27823.1 - 3.7e-15 56.1 0.0 8.6e-15 54.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EER27823.1 - 3.8e-06 27.1 0.0 7.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EER27823.1 - 0.0085 16.3 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EER27823.1 - 0.029 14.7 0.0 0.054 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EER27823.1 - 0.036 14.8 0.0 0.092 13.5 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain DDOST_48kD PF03345.14 EER27826.1 - 5.2e-156 519.7 0.0 5.9e-156 519.5 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pet191_N PF10203.9 EER27827.1 - 1.4e-27 95.7 6.0 1.8e-27 95.4 6.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COBRA PF04833.15 EER27827.1 - 0.014 15.3 0.2 0.016 15.1 0.2 1.2 1 0 0 1 1 1 0 COBRA-like protein PAN_3 PF08277.12 EER27827.1 - 0.074 12.9 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 PAN-like domain CX9C PF16860.5 EER27827.1 - 0.091 12.8 8.3 1.8 8.7 1.1 2.8 1 1 2 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EER27827.1 - 0.34 11.0 3.4 12 6.1 0.3 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydrolase_1 PF00561.20 EER27828.1 - 1.8e-23 83.5 0.1 5.2e-23 82.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EER27828.1 - 6.2e-23 80.2 0.1 1.2e-22 79.2 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EER27828.1 - 0.0001 21.7 0.0 0.048 12.9 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EER27828.1 - 0.00013 21.7 0.0 0.061 13.0 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Ras PF00071.22 EER27829.1 - 2.6e-52 176.7 0.0 3.1e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER27829.1 - 1.3e-18 67.4 0.0 2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER27829.1 - 1.8e-11 43.8 0.0 2.2e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EER27829.1 - 2.4e-06 27.2 0.0 2.1e-05 24.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EER27829.1 - 7.3e-05 22.8 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER27829.1 - 0.00015 21.8 0.1 0.63 9.9 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EER27829.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EER27829.1 - 0.029 14.6 0.2 0.41 10.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EER27829.1 - 0.12 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EER27829.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 EER27829.1 - 0.17 12.3 0.8 0.83 10.0 0.8 2.2 1 1 0 1 1 1 0 AAA ATPase domain Carboxyl_trans PF01039.22 EER27830.1 - 6.1e-140 467.1 0.1 8.2e-140 466.7 0.1 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 EER27831.1 - 7e-39 133.4 0.5 1.1e-38 132.8 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EER27831.1 - 4.6e-32 111.0 0.1 8.4e-32 110.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EER27831.1 - 1e-27 96.2 0.2 2e-27 95.2 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EER27831.1 - 5.1e-14 52.7 0.1 8.1e-14 52.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EER27831.1 - 8.9e-06 25.6 0.1 2.6e-05 24.0 0.1 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CPSase_L_D2 PF02786.17 EER27833.1 - 1.6e-75 253.2 0.0 2.5e-75 252.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EER27833.1 - 8.3e-35 119.7 0.0 1.8e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EER27833.1 - 1.5e-34 118.3 0.0 3.9e-34 117.0 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EER27833.1 - 3.7e-18 65.1 0.6 9.7e-18 63.8 0.6 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EER27833.1 - 3.7e-11 43.0 0.0 7.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EER27833.1 - 2.6e-09 36.9 0.0 4.6e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EER27833.1 - 2.6e-05 23.9 0.0 0.029 14.2 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EER27833.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EER27833.1 - 0.0019 18.9 0.0 0.83 10.4 0.0 2.9 3 0 0 3 3 2 1 HlyD family secretion protein GARS_A PF01071.19 EER27833.1 - 0.0029 17.4 0.0 0.0049 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 EER27833.1 - 0.0036 16.6 0.0 0.0072 15.6 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EER27833.1 - 0.022 14.6 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein RimK PF08443.11 EER27833.1 - 0.029 14.0 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 EER27833.1 - 0.032 13.5 0.0 4.5 6.4 0.0 2.5 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion adh_short_C2 PF13561.6 EER27834.1 - 4.8e-53 180.1 0.0 7.5e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER27834.1 - 6.3e-38 130.2 0.1 9.5e-38 129.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER27834.1 - 2.6e-12 47.0 0.3 3.7e-12 46.5 0.3 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EER27834.1 - 0.0078 15.7 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_2 PF12796.7 EER27835.1 - 5.9e-30 103.7 0.0 1.6e-11 44.7 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER27835.1 - 7.1e-27 93.4 1.1 7.9e-07 29.5 0.0 5.7 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EER27835.1 - 2e-25 88.5 0.2 2e-09 37.5 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EER27835.1 - 2.5e-23 81.4 1.3 3.3e-07 30.4 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EER27835.1 - 1.1e-22 77.6 0.1 0.00045 20.5 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat F-box PF00646.33 EER27835.1 - 0.038 13.9 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 EER27835.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 EER27835.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 F-box-like HEM4 PF02602.15 EER27835.1 - 0.084 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD MARVEL PF01284.23 EER27837.1 - 2.7e-07 30.7 9.0 4.5e-07 30.0 9.0 1.4 1 1 0 1 1 1 1 Membrane-associating domain DUF2339 PF10101.9 EER27837.1 - 0.0001 21.1 0.7 0.00012 20.9 0.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) TrbC PF04956.13 EER27837.1 - 0.083 13.1 3.9 0.14 12.4 0.1 2.5 2 1 0 2 2 2 0 TrbC/VIRB2 family DUF4293 PF14126.6 EER27837.1 - 0.1 12.8 1.4 0.23 11.7 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) NB PF04159.13 EER27837.1 - 0.3 11.1 1.1 0.77 9.8 0.0 2.1 1 1 2 3 3 3 0 NB glycoprotein PHD PF00628.29 EER27839.1 - 1.1e-09 38.0 1.2 1.1e-09 38.0 1.2 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EER27839.1 - 0.001 18.6 2.2 0.0016 17.9 2.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EER27839.1 - 0.19 11.8 1.4 0.52 10.4 1.4 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger UIM PF02809.20 EER27839.1 - 0.24 11.4 3.2 0.76 9.8 3.2 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif eIF-5a PF01287.20 EER27840.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold RCR PF12273.8 EER27840.1 - 0.1 13.3 0.4 0.1 13.3 0.4 2.1 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Peptidase_M28 PF04389.17 EER27842.1 - 4.1e-30 105.0 0.0 6.7e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EER27842.1 - 6.3e-05 22.8 0.1 0.00016 21.4 0.1 1.7 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Xin PF08043.12 EER27842.1 - 0.053 13.2 0.3 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 Xin repeat SRR1 PF07985.12 EER27844.1 - 1.8e-16 59.9 0.0 4.1e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 SRR1 Isochorismatase PF00857.20 EER27845.1 - 2.8e-42 144.9 0.0 3.2e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_17 PF00332.18 EER27846.1 - 3.1e-07 30.3 3.8 2.3e-06 27.5 1.6 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DHHC PF01529.20 EER27850.1 - 2.3e-25 89.3 10.2 2.6e-25 89.1 7.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase TMEM208_SND2 PF05620.11 EER27850.1 - 0.074 12.8 0.0 0.074 12.8 0.0 2.4 2 1 1 3 3 3 0 SRP-independent targeting protein 2/TMEM208 FAD_binding_3 PF01494.19 EER27852.1 - 1.1e-19 70.9 2.3 7.5e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EER27852.1 - 2.9e-09 37.0 0.9 1e-08 35.3 0.8 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EER27852.1 - 1.5e-08 34.2 0.2 2.7e-08 33.4 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EER27852.1 - 2.9e-07 30.2 0.4 4.2e-07 29.7 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EER27852.1 - 7.1e-06 25.8 6.5 7.5e-06 25.8 4.9 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EER27852.1 - 2e-05 23.9 5.4 5.9e-05 22.3 4.3 2.0 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.22 EER27852.1 - 2.9e-05 23.3 1.1 4.7e-05 22.7 1.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EER27852.1 - 0.00013 21.1 0.5 0.00018 20.7 0.5 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 EER27852.1 - 0.00038 21.0 0.8 0.00038 21.0 0.8 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER27852.1 - 0.0028 16.4 1.8 0.0046 15.7 1.8 1.3 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 EER27852.1 - 0.014 14.3 1.9 0.1 11.4 1.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EER27852.1 - 0.015 14.6 0.5 0.031 13.6 0.5 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 EER27852.1 - 0.034 13.4 1.3 0.073 12.3 0.3 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.23 EER27852.1 - 0.067 13.2 0.4 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.17 EER27852.1 - 0.073 12.3 0.2 0.16 11.2 0.2 1.5 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 EER27852.1 - 0.11 12.1 1.9 0.24 11.0 1.9 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EER27852.1 - 0.2 11.5 1.1 0.41 10.5 1.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 EER27852.1 - 0.22 10.3 0.5 0.42 9.4 0.3 1.4 2 0 0 2 2 2 0 MCRA family MerR-DNA-bind PF09278.11 EER27852.1 - 0.23 12.0 0.1 0.48 11.0 0.1 1.5 1 0 0 1 1 1 0 MerR, DNA binding Pyr_redox_3 PF13738.6 EER27852.1 - 0.66 9.2 5.5 0.21 10.8 1.5 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 EER27853.1 - 5.8e-10 38.6 0.1 1.3e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER27853.1 - 0.00041 20.4 7.6 0.00076 19.6 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-B_dimeris PF09026.10 EER27853.1 - 1 9.8 4.3 2.3 8.7 4.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C3H1 PF10650.9 EER27854.1 - 3.2e-10 39.5 3.2 5.1e-10 38.9 3.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain HMMR_N PF15905.5 EER27854.1 - 0.0085 15.6 1.7 0.029 13.8 1.7 1.9 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Myosin_head PF00063.21 EER27855.1 - 1.7e-266 885.8 0.0 1.7e-266 885.8 0.0 2.6 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EER27855.1 - 1.5e-16 59.5 277.0 8.2e-12 43.8 123.0 7.0 2 2 2 4 4 4 3 Myosin tail Myosin_N PF02736.19 EER27855.1 - 1e-09 38.1 0.0 2.3e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EER27855.1 - 0.04 14.2 0.0 0.04 14.2 0.0 5.4 5 0 0 5 5 5 0 AAA domain TcdB_N PF12918.7 EER27855.1 - 0.25 11.7 8.9 3.3 8.1 0.4 4.8 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain Sigma54_activ_2 PF14532.6 EER27855.1 - 1.1 9.4 14.0 2.6 8.2 1.5 4.7 4 0 0 4 4 4 0 Sigma-54 interaction domain Abhydrolase_1 PF00561.20 EER27856.1 - 6.4e-46 157.1 0.0 3.3e-45 154.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EER27856.1 - 0.00022 20.9 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase ThiF PF00899.21 EER27857.1 - 8.2e-40 136.7 0.0 1.3e-39 136.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EER27857.1 - 0.0033 17.7 0.3 1.9 8.8 0.1 2.4 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EER27857.1 - 0.063 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EER27857.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Metallophos PF00149.28 EER27858.1 - 2.7e-09 37.8 0.0 4.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EER27858.1 - 4.9e-05 23.6 0.0 0.00013 22.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EER27858.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily MARVEL PF01284.23 EER27859.1 - 1.8e-20 73.4 11.1 2.3e-20 73.1 11.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 EER27859.1 - 0.049 13.2 1.6 0.088 12.4 1.7 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4336 PF14234.6 EER27860.1 - 1.1e-15 57.6 0.3 4.4e-11 42.6 0.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.10 EER27861.1 - 1.4e-33 115.0 0.0 3.7e-33 113.6 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EER27861.1 - 7.8e-15 54.7 0.2 2.2e-14 53.3 0.2 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1351 PF07083.11 EER27861.1 - 0.13 12.0 1.2 0.14 11.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) PI3Ka PF00613.20 EER27862.1 - 4.8e-61 205.4 0.8 9.8e-61 204.4 0.8 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EER27862.1 - 3.4e-46 158.1 0.0 1.1e-30 107.3 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EER27862.1 - 1.6e-31 109.1 0.0 3e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.30 EER27862.1 - 0.004 17.4 0.0 0.0094 16.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain HEAT_2 PF13646.6 EER27862.1 - 0.18 12.2 1.3 1.6 9.1 0.3 2.7 3 0 0 3 3 3 0 HEAT repeats MMR_HSR1 PF01926.23 EER27863.1 - 1.3e-12 47.8 0.0 5.6e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EER27863.1 - 0.0002 21.3 0.0 0.00064 19.7 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EER27863.1 - 0.0059 16.2 0.0 0.012 15.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EER27863.1 - 0.073 13.1 0.0 0.5 10.4 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Isy1 PF06246.12 EER27864.1 - 3.9e-87 292.0 0.0 4.7e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Isy1-like splicing family Gly_transf_sug PF04488.15 EER27866.1 - 9.2e-14 51.9 0.0 2.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EER27866.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Pkinase PF00069.25 EER27867.1 - 4.2e-65 219.7 0.0 5.1e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27867.1 - 1.8e-33 115.9 0.0 2.4e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER27867.1 - 0.0018 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EER27867.1 - 0.0093 15.9 0.0 0.23 11.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EER27867.1 - 0.01 14.8 0.1 0.013 14.4 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 EER27867.1 - 0.13 11.8 0.1 0.59 9.7 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ATP-synt_C PF00137.21 EER27868.1 - 4.5e-31 107.0 34.9 3.6e-18 65.7 14.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.22 EER27869.1 - 3e-80 269.8 0.0 2.7e-79 266.7 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EER27869.1 - 9.5e-41 139.1 0.0 1.9e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EER27869.1 - 3.3e-39 135.0 0.1 5.8e-39 134.2 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EER27869.1 - 5.7e-14 51.9 0.0 1.5e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Septin PF00735.18 EER27870.1 - 6.2e-109 363.6 0.2 1e-108 362.9 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EER27870.1 - 2.6e-05 24.3 0.0 6.8e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EER27870.1 - 0.0024 17.9 4.5 1.4 9.0 0.0 3.2 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 EER27870.1 - 0.0039 17.1 3.2 0.0067 16.3 0.3 2.6 3 1 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 EER27870.1 - 0.0043 16.6 0.2 0.35 10.4 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EER27870.1 - 0.026 13.8 0.0 0.066 12.5 0.0 1.7 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 EER27870.1 - 0.16 12.5 0.5 1.7 9.2 0.0 2.6 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 EER27870.1 - 0.17 12.4 8.1 2.4 8.6 4.4 2.2 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EER27870.1 - 0.24 11.7 2.2 0.24 11.7 0.2 2.1 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 EER27871.1 - 0.00078 20.2 3.6 2.3 9.3 0.0 3.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Nbas_N PF15492.6 EER27871.1 - 0.017 14.4 0.0 0.83 8.9 0.0 2.3 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 EER27871.1 - 0.057 13.7 0.0 2.5 8.5 0.0 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EER27871.1 - 0.17 10.8 0.0 0.42 9.5 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RRM_1 PF00076.22 EER27872.1 - 1.9e-19 69.2 0.0 4.6e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER27872.1 - 1.8e-05 24.8 0.0 6.2e-05 23.0 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif Sigma70_r1_2 PF00140.20 EER27872.1 - 0.024 14.6 0.5 0.071 13.1 0.5 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 OB_RNB PF08206.11 EER27872.1 - 0.12 12.0 0.2 0.84 9.4 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF572 PF04502.13 EER27872.1 - 1.1 8.9 17.3 1.4 8.5 17.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) SelP_N PF04592.14 EER27872.1 - 4.4 6.7 19.2 8.4 5.7 0.1 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DLIC PF05783.11 EER27873.1 - 1.6e-35 122.9 1.5 2.9e-31 108.8 0.0 4.0 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) Peptidase_S9 PF00326.21 EER27874.1 - 4.2e-49 166.9 0.0 6.7e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EER27874.1 - 3.2e-07 30.1 0.2 0.056 13.4 0.0 4.5 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EER27874.1 - 0.015 14.0 0.1 3.5 6.3 0.0 3.2 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Lipoprotein_15 PF03640.15 EER27874.1 - 0.016 14.7 0.1 0.05 13.2 0.0 1.9 2 0 0 2 2 2 0 Secreted repeat of unknown function Peptidase_S9_N PF02897.15 EER27874.1 - 0.045 12.5 0.8 0.68 8.7 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_C12 PF01088.21 EER27875.1 - 1.3e-44 152.5 0.0 1.6e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Y_phosphatase3 PF13350.6 EER27876.1 - 1.4e-63 215.0 0.0 1.6e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EER27876.1 - 6.4e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EER27876.1 - 0.0083 15.7 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EER27876.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Spermine_synth PF01564.17 EER27877.1 - 2e-08 33.9 0.0 3.3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoHcyase_NAD PF00670.21 EER27877.1 - 0.045 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Tma16 PF11176.8 EER27877.1 - 0.21 11.5 0.0 0.35 10.7 0.0 1.2 1 0 0 1 1 1 0 Translation machinery-associated protein 16 DUF2052 PF09747.9 EER27878.1 - 1.9e-23 83.7 20.8 5.5e-12 46.2 13.1 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Pkinase PF00069.25 EER27879.1 - 3.3e-52 177.4 0.0 4.6e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27879.1 - 6.6e-27 94.4 0.0 6.1e-26 91.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EER27879.1 - 0.079 12.3 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AMP-binding PF00501.28 EER27880.1 - 4.1e-70 236.5 0.3 4.9e-70 236.3 0.3 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER27880.1 - 5.5e-14 52.9 0.1 1.7e-13 51.4 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Spt5_N PF11942.8 EER27881.1 - 0.0012 19.8 3.4 0.0045 17.9 3.4 2.0 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal Aquarius_N PF16399.5 EER27881.1 - 0.079 11.0 0.8 0.097 10.7 0.0 1.5 2 0 0 2 2 2 0 Intron-binding protein aquarius N-terminus Dynactin_p22 PF07426.11 EER27882.1 - 5e-07 29.7 0.0 7.8e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 SH3_1 PF00018.28 EER27883.1 - 3.4e-09 36.1 0.7 6e-09 35.4 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EER27883.1 - 1.3e-07 31.4 0.0 1.2e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EER27883.1 - 5.2e-06 26.0 0.0 1.5e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_10 PF17902.1 EER27883.1 - 0.13 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Response_reg PF00072.24 EER27884.1 - 6.2e-21 74.7 0.0 8.2e-15 55.0 0.0 2.3 1 1 1 2 2 2 2 Response regulator receiver domain Bot1p PF12298.8 EER27885.1 - 3.1e-56 190.2 0.8 3.1e-56 190.2 0.8 2.0 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein RRM_1 PF00076.22 EER27886.1 - 3.5e-15 55.6 0.0 1.2e-11 44.3 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_7 PF13508.7 EER27887.1 - 1.6e-08 34.8 0.0 2.2e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER27887.1 - 1.4e-07 31.5 0.0 2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER27887.1 - 2.1e-07 31.2 0.0 2.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EER27887.1 - 2.1e-05 24.4 0.0 3.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EER27887.1 - 0.0003 20.9 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MpPF1 PF07668.11 EER27888.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 M penetrans paralogue family 1 Ribosomal_S16 PF00886.19 EER27889.1 - 5e-25 87.3 0.0 7.6e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 EER27890.1 - 4.5e-36 124.3 0.0 6e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.25 EER27890.1 - 0.042 13.3 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme PUL PF08324.11 EER27891.1 - 6.3e-73 245.4 9.4 9e-73 244.9 9.4 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EER27891.1 - 3.5e-45 152.9 0.5 6.4e-45 152.1 0.5 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EER27891.1 - 1.9e-30 104.4 17.3 1.8e-06 28.6 0.0 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 EER27891.1 - 0.15 12.1 0.0 6.5 6.8 0.0 2.8 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 EER27892.1 - 9.9e-20 70.5 11.7 3e-06 27.8 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27892.1 - 2.9e-06 27.5 0.0 0.32 11.3 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER27892.1 - 6e-05 21.9 0.1 0.18 10.4 0.0 2.5 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EER27892.1 - 0.015 14.3 0.0 0.67 8.8 0.0 2.6 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 EER27892.1 - 0.046 12.6 0.0 3.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) RRM_1 PF00076.22 EER27893.1 - 3.1e-18 65.3 0.0 5.2e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EER27893.1 - 1.7e-06 28.5 6.4 1.7e-06 28.5 6.4 3.8 3 1 1 4 4 4 2 C-terminal duplication domain of Friend of PRMT1 CH PF00307.31 EER27894.1 - 3.9e-46 155.7 0.1 4.9e-22 78.2 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EER27894.1 - 1.7e-26 92.1 0.1 4.5e-26 90.7 0.1 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EER27894.1 - 2.3e-09 37.0 0.3 1.1e-05 25.2 0.0 2.8 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_8 PF13833.6 EER27894.1 - 0.0011 18.8 0.3 0.0054 16.5 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EER27894.1 - 0.0015 18.3 1.7 0.0053 16.6 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 EER27894.1 - 0.0065 15.9 0.1 0.083 12.5 0.0 2.7 2 0 0 2 2 2 1 EF hand Spectrin PF00435.21 EER27894.1 - 0.025 15.1 9.8 0.51 10.8 0.0 2.8 3 0 0 3 3 3 0 Spectrin repeat FliG_N PF14842.6 EER27894.1 - 0.28 11.8 1.4 2.7 8.6 0.1 2.9 2 1 0 3 3 3 0 FliG N-terminal domain G-alpha PF00503.20 EER27895.1 - 2.1e-122 408.7 1.2 2.5e-122 408.5 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EER27895.1 - 4.7e-16 58.7 0.5 1.2e-10 41.2 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EER27895.1 - 7.6e-05 22.4 0.0 0.00033 20.4 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EER27895.1 - 0.00094 18.6 3.4 0.034 13.5 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EER27895.1 - 0.0093 16.2 0.5 1.8 8.8 0.0 2.8 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EER27895.1 - 0.013 15.2 0.1 0.036 13.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 EER27895.1 - 0.034 13.3 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain NB-ARC PF00931.22 EER27895.1 - 0.055 12.6 0.1 0.089 12.0 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain GTP_EFTU PF00009.27 EER27895.1 - 0.064 12.8 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EER27895.1 - 0.099 12.7 0.0 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EER27895.1 - 0.14 11.5 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Use1 PF09753.9 EER27896.1 - 7.4e-11 42.2 2.6 1.9e-10 40.9 2.6 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF745 PF05335.13 EER27896.1 - 0.001 18.9 5.7 0.093 12.4 0.5 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF745) Ubiquitin_5 PF18037.1 EER27896.1 - 0.018 15.4 0.1 12 6.4 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2730 PF10805.8 EER27896.1 - 0.17 12.0 1.7 0.21 11.7 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DivIC PF04977.15 EER27896.1 - 2 8.2 5.5 0.16 11.8 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator AMP-binding PF00501.28 EER27897.1 - 1.6e-97 326.8 0.0 2.1e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER27897.1 - 1.4e-14 54.8 0.1 1.4e-14 54.8 0.1 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Nup188_C PF18378.1 EER27898.1 - 1.4e-143 478.2 0.0 2.2e-143 477.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EER27898.1 - 6.9e-78 262.6 0.1 1.2e-68 231.9 0.1 2.4 2 0 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.21 EER27899.1 - 2.3e-94 315.3 0.0 3.6e-94 314.7 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EER27899.1 - 8.4e-52 175.8 0.0 1.1e-48 165.6 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EER27899.1 - 2.1e-48 164.6 0.0 3.5e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EER27899.1 - 0.00061 19.6 0.3 0.0025 17.6 0.3 1.9 1 1 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.21 EER27899.1 - 0.0055 16.2 0.2 0.036 13.5 0.1 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein QRPTase_C PF01729.19 EER27899.1 - 0.0058 16.4 0.4 0.15 11.8 0.1 2.6 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.14 EER27899.1 - 0.0062 15.7 0.3 0.023 13.9 0.1 2.0 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase YjeF_N PF03853.15 EER27899.1 - 0.064 13.1 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus Peripla_BP_2 PF01497.18 EER27899.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein PTCB-BRCT PF12738.7 EER27900.1 - 8.2e-09 35.3 0.2 1.7e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EER27900.1 - 1.2e-08 35.2 0.1 2.3e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EER27900.1 - 2.7e-05 24.5 0.0 5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 EER27900.1 - 0.0049 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 WGR domain LIG3_BRCT PF16759.5 EER27900.1 - 0.0069 16.7 0.3 0.024 14.9 0.1 1.9 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain Brix PF04427.18 EER27901.1 - 2.9e-31 109.1 0.0 3.7e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.10 EER27902.1 - 2.7e-71 238.5 3.7 2.7e-71 238.5 3.7 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EER27902.1 - 1.9e-58 197.4 0.0 3e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EER27902.1 - 1.4e-51 175.8 3.5 1.2e-29 103.9 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EER27902.1 - 8e-33 112.5 0.0 2.2e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EER27902.1 - 3.9e-13 49.5 0.1 4.4e-12 46.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EER27902.1 - 1.1e-09 38.8 0.0 9.1e-09 35.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EER27902.1 - 4.8e-06 26.7 0.0 9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EER27902.1 - 0.00056 19.7 0.2 1.7 8.4 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EER27902.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 EER27902.1 - 0.003 16.9 0.2 0.063 12.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 EER27902.1 - 0.0068 15.6 0.0 0.95 8.6 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.29 EER27902.1 - 0.017 14.9 0.1 0.036 13.8 0.1 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 EER27902.1 - 0.04 13.4 0.0 0.25 10.8 0.0 2.2 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_10 PF12846.7 EER27902.1 - 0.061 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PhoH PF02562.16 EER27902.1 - 0.096 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Ribosomal_S13_N PF08069.12 EER27902.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.9 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain ATPase PF06745.13 EER27902.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC AhpC-TSA_2 PF13911.6 EER27903.1 - 2e-15 56.9 0.0 3.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EER27903.1 - 8.7e-05 22.4 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EER27903.1 - 0.024 14.4 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Redoxin adh_short_C2 PF13561.6 EER27904.1 - 9.8e-62 208.6 3.2 1.2e-61 208.3 3.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER27904.1 - 1.5e-46 158.3 1.5 1.8e-46 158.1 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER27904.1 - 2.3e-06 27.6 0.1 3.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 KR domain SWIRM-assoc_3 PF16498.5 EER27904.1 - 0.023 14.9 0.6 0.055 13.7 0.6 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal Methyltransf_25 PF13649.6 EER27904.1 - 0.087 13.5 0.1 0.17 12.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain PI-PLC-X PF00388.19 EER27905.1 - 3.9e-60 201.7 0.0 7.3e-60 200.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EER27905.1 - 1.6e-42 144.5 0.0 3e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EER27905.1 - 3.7e-05 24.0 0.0 0.00058 20.1 0.0 2.5 1 1 0 1 1 1 1 C2 domain EF-hand_like PF09279.11 EER27905.1 - 0.00058 20.3 0.0 0.0014 19.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 EER27905.1 - 0.00099 18.5 0.9 0.0079 15.7 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EER27905.1 - 0.014 15.8 2.4 0.13 12.8 1.6 2.7 2 1 0 2 2 2 0 EF-hand domain pair GDPD PF03009.17 EER27905.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_6 PF13405.6 EER27905.1 - 0.59 10.2 1.9 2.4 8.3 0.1 2.8 2 1 0 3 3 3 0 EF-hand domain Herpes_pp85 PF04637.12 EER27905.1 - 8 4.8 6.8 0.8 8.1 0.2 2.1 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Glyco_hydro_61 PF03443.14 EER27906.1 - 0.0009 19.2 0.0 0.0036 17.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 61 LPMO_10 PF03067.15 EER27906.1 - 0.0016 19.1 0.0 0.0035 18.0 0.0 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Sec5 PF15469.6 EER27907.1 - 4e-36 124.6 0.2 1e-35 123.3 0.1 1.8 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 EER27907.1 - 3.5e-05 23.8 0.1 0.00014 21.9 0.1 2.1 1 0 0 1 1 1 1 Vps51/Vps67 GTP-bdg_M PF16360.5 EER27907.1 - 1.2 9.8 6.2 1.4 9.6 0.5 3.3 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region Iso_dh PF00180.20 EER27908.1 - 8.1e-101 337.6 0.0 1e-100 337.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 EER27908.1 - 0.061 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 EER27908.1 - 0.065 13.3 0.0 0.59 10.3 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Eaf7 PF07904.13 EER27909.1 - 2.5e-21 76.0 0.1 3.6e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Chromatin modification-related protein EAF7 GCP_C_terminal PF04130.13 EER27910.1 - 3e-69 233.9 0.3 4.1e-69 233.4 0.3 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EER27910.1 - 2.5e-32 112.7 0.1 5.2e-32 111.7 0.1 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal rRNA_processing PF08524.11 EER27911.1 - 0.088 12.8 23.1 0.5 10.4 23.1 2.1 1 1 0 1 1 1 0 rRNA processing Presenilin PF01080.17 EER27911.1 - 1.7 7.4 5.6 2 7.1 5.6 1.1 1 0 0 1 1 1 0 Presenilin DUF4210 PF13915.6 EER27912.1 - 2.8e-31 107.9 0.1 9.5e-31 106.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EER27912.1 - 6.1e-24 83.9 0.3 1.3e-23 82.9 0.3 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.19 EER27913.1 - 3.1e-113 378.5 0.4 3.1e-113 378.5 0.4 1.7 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EER27913.1 - 1.8e-56 190.1 1.5 1.8e-56 190.1 1.5 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EER27913.1 - 0.7 9.6 5.2 2.6 7.8 2.8 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C DUF2457 PF10446.9 EER27913.1 - 3.3 6.7 9.3 0.12 11.5 3.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PfkB PF00294.24 EER27914.1 - 2.7e-18 66.3 0.0 4.2e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribonucleas_3_3 PF14622.6 EER27916.1 - 1.1e-07 32.1 0.0 0.0013 18.9 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EER27916.1 - 4.3e-07 30.5 0.0 1.8e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EER27916.1 - 4e-05 24.2 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif ECH_1 PF00378.20 EER27917.1 - 1.2e-22 80.5 0.0 1.7e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER27917.1 - 0.00033 20.3 0.0 0.0005 19.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Synapsin_C PF02750.14 EER27917.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Synapsin, ATP binding domain BSP PF04450.12 EER27918.1 - 1.4e-68 230.8 0.0 1.6e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria DUF2268 PF10026.9 EER27918.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 EER27918.1 - 0.24 11.3 0.7 0.39 10.6 0.1 1.6 2 0 0 2 2 2 0 SprT-like family CLASP_N PF12348.8 EER27919.1 - 4.8e-151 500.6 0.0 2.7e-90 301.9 0.0 2.7 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 EER27919.1 - 2.4e-07 30.4 0.0 1.1 9.6 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 EER27919.1 - 0.00021 21.6 0.3 5 7.6 0.0 5.0 5 0 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 EER27919.1 - 0.0015 18.6 0.0 1.6 8.8 0.0 3.9 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Acetyltransf_8 PF13523.6 EER27920.1 - 4e-46 156.3 3.0 5.6e-46 155.8 3.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1579 PF07617.11 EER27920.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1579) Acetyltransf_3 PF13302.7 EER27920.1 - 0.1 13.3 0.3 0.19 12.4 0.3 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 EER27921.1 - 1.7e-89 300.1 22.3 5.6e-45 154.1 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EER27921.1 - 3.1e-64 215.6 0.0 1.2e-30 106.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EER27921.1 - 1.6e-16 60.4 2.5 8.2e-06 25.4 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EER27921.1 - 4.4e-10 38.9 0.1 0.0013 17.6 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EER27921.1 - 9.2e-08 32.6 2.1 0.00031 21.2 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EER27921.1 - 1.8e-07 30.8 2.4 0.0032 17.2 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EER27921.1 - 2.2e-07 31.2 0.4 0.1 12.8 0.0 4.2 4 0 0 4 4 4 2 AAA domain DUF87 PF01935.17 EER27921.1 - 3.1e-07 30.7 0.0 0.0019 18.4 0.0 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 EER27921.1 - 4.8e-07 29.7 0.4 0.24 11.1 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 EER27921.1 - 0.00031 20.6 0.0 0.91 9.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EER27921.1 - 0.00066 20.2 0.0 0.36 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EER27921.1 - 0.00082 19.3 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EER27921.1 - 0.00084 19.2 1.4 4.4 7.0 0.1 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF3987 PF13148.6 EER27921.1 - 0.00086 18.4 0.0 0.24 10.4 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) Rad17 PF03215.15 EER27921.1 - 0.0026 17.7 0.0 0.95 9.3 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 EER27921.1 - 0.0028 17.3 0.0 0.93 9.1 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 EER27921.1 - 0.0041 17.3 5.3 2.4 8.5 0.5 4.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EER27921.1 - 0.0069 16.6 0.1 6.4 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EER27921.1 - 0.0098 15.6 0.2 3.2 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EER27921.1 - 0.01 15.4 0.0 4.2 6.9 0.0 3.2 3 0 0 3 3 2 0 AAA domain G-alpha PF00503.20 EER27921.1 - 0.011 14.9 0.0 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 EER27921.1 - 0.013 15.5 0.0 13 5.8 0.0 3.3 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EER27921.1 - 0.015 14.7 0.0 0.34 10.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EER27921.1 - 0.027 14.0 0.0 6 6.3 0.0 2.9 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_18 PF13238.6 EER27921.1 - 0.03 14.9 0.0 14 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MTH865 PF07747.11 EER27921.1 - 0.039 13.7 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 0 MTH865-like family AAA_17 PF13207.6 EER27921.1 - 0.042 14.3 0.1 11 6.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 EER27921.1 - 0.066 13.0 2.0 8.9 6.0 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.7 EER27921.1 - 0.076 11.9 0.0 3.2 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.12 EER27921.1 - 0.098 11.9 0.0 13 5.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 EER27921.1 - 0.14 11.9 0.3 13 5.4 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RhoGAP PF00620.27 EER27922.1 - 1.8e-46 157.7 0.0 7.3e-46 155.8 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.22 EER27922.1 - 1.5e-13 50.8 19.1 6e-09 36.0 3.0 2.4 2 0 0 2 2 2 2 LIM domain TF_Zn_Ribbon PF08271.12 EER27922.1 - 1.8 8.1 16.4 12 5.5 0.1 4.4 3 1 0 3 3 3 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 EER27922.1 - 2.3 8.2 15.1 1.2 9.2 0.6 3.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain CENP-H PF05837.12 EER27922.1 - 4.6 7.7 13.4 0.089 13.2 1.6 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF536 PF04394.14 EER27922.1 - 5.3 7.0 7.4 1.1 9.2 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF536 Zn-ribbon_8 PF09723.10 EER27922.1 - 6.6 6.9 18.8 1.8 8.7 1.3 4.2 3 1 1 4 4 4 0 Zinc ribbon domain DASH_Ask1 PF08655.10 EER27923.1 - 6.2e-31 106.1 0.6 9.6e-31 105.5 0.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Spore_III_AB PF09548.10 EER27923.1 - 0.095 12.8 0.2 0.42 10.7 0.3 1.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) LicD PF04991.13 EER27925.1 - 7.4e-23 81.9 9.4 1.5e-16 61.3 3.7 2.3 1 1 1 2 2 2 2 LicD family WLM PF08325.10 EER27926.1 - 4.5e-50 170.4 0.0 9.1e-50 169.4 0.0 1.5 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 EER27926.1 - 8.4e-05 22.7 2.3 0.00013 22.1 0.7 2.0 2 1 1 3 3 3 1 Protein of unknown function DUF45 PB1 PF00564.24 EER27926.1 - 0.00057 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 PB1 domain ubiquitin PF00240.23 EER27926.1 - 0.0013 18.4 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family SprT-like PF10263.9 EER27926.1 - 0.019 14.8 2.4 0.032 14.1 2.4 1.5 1 1 0 1 1 1 0 SprT-like family Thiolase_N PF00108.23 EER27927.1 - 1.9e-67 227.4 0.1 2.6e-67 226.9 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EER27927.1 - 1.6e-42 144.1 0.3 3.3e-42 143.0 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EER27927.1 - 0.01 15.4 0.7 0.072 12.6 0.6 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain HSP70 PF00012.20 EER27928.1 - 2e-164 548.1 4.8 2e-164 548.1 4.8 2.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EER27928.1 - 1.8e-10 40.1 0.0 6.2e-10 38.4 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EER27928.1 - 0.0022 18.4 0.2 4.5 7.8 0.0 3.2 2 1 0 2 2 2 2 Cell division protein FtsA GRIN_C PF15235.6 EER27928.1 - 5.8 7.1 11.9 11 6.3 11.3 1.8 1 1 0 1 1 1 0 G protein-regulated inducer of neurite outgrowth C-terminus Chitin_synth_2 PF03142.15 EER27929.1 - 5.4e-23 81.4 6.9 4.5e-22 78.4 5.0 2.5 2 2 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EER27929.1 - 6e-15 55.7 8.1 6e-15 55.7 8.1 2.7 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EER27929.1 - 2.5e-10 40.6 0.0 6.6e-10 39.3 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EER27929.1 - 0.024 14.4 0.2 7.2 6.4 0.1 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 CybS PF05328.12 EER27929.1 - 0.054 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 CybS, succinate dehydrogenase cytochrome B small subunit La PF05383.17 EER27930.1 - 6.3e-21 74.2 0.0 1.1e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EER27930.1 - 7.4e-07 28.9 0.1 1.8e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5320 PF17253.2 EER27930.1 - 0.97 10.5 11.2 0.54 11.3 8.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DAO PF01266.24 EER27931.1 - 9e-51 173.5 0.2 1e-50 173.3 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EER27931.1 - 3.5e-06 26.5 0.0 4.6e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER27931.1 - 0.00066 19.0 0.1 0.0011 18.3 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EER27931.1 - 0.00073 19.6 0.1 0.42 10.6 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Mqo PF06039.15 EER27931.1 - 0.0033 16.0 0.0 0.044 12.4 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 EER27931.1 - 0.016 14.4 0.5 0.55 9.4 0.3 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER27931.1 - 0.024 13.8 0.1 0.071 12.2 0.0 1.7 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EER27931.1 - 0.035 12.8 0.6 0.63 8.7 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.6 EER27931.1 - 0.036 14.3 0.3 0.036 14.3 0.3 1.8 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain PALP PF00291.25 EER27931.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme FAD_binding_2 PF00890.24 EER27931.1 - 7.2 5.6 10.5 0.96 8.5 0.5 2.4 3 0 0 3 3 2 0 FAD binding domain MFS_1 PF07690.16 EER27932.1 - 3.5e-32 111.7 26.5 3.5e-32 111.7 26.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 EER27932.1 - 0.00067 18.6 3.7 0.0023 16.9 1.6 2.1 2 0 0 2 2 2 1 POT family TRI12 PF06609.13 EER27932.1 - 0.0026 16.3 3.3 0.0044 15.5 3.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Cu_amine_oxid PF01179.20 EER27933.1 - 2.7e-164 547.0 0.0 3.3e-164 546.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EER27933.1 - 7.5e-05 23.1 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EER27933.1 - 0.011 15.9 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Rad51 PF08423.11 EER27934.1 - 3.3e-37 128.1 0.0 3.9e-35 121.4 0.0 2.2 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EER27934.1 - 2.2e-09 37.2 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EER27934.1 - 3.1e-06 26.7 0.2 4.4e-05 23.0 0.2 2.1 1 1 0 1 1 1 1 KaiC RecA PF00154.21 EER27934.1 - 0.0029 17.1 0.1 0.015 14.7 0.1 2.0 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_16 PF13191.6 EER27934.1 - 0.046 14.1 0.0 0.14 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EER27934.1 - 0.074 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EER27934.1 - 0.077 13.3 0.4 0.46 10.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EER27934.1 - 0.14 12.7 0.1 0.45 11.0 0.1 1.8 1 0 0 1 1 1 0 ABC transporter FA_desaturase PF00487.24 EER27935.1 - 8.6e-24 84.7 17.5 2e-23 83.6 17.5 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EER27935.1 - 6.8e-06 26.3 0.0 2.6e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) TRAPPC10 PF12584.8 EER27936.1 - 7.7e-42 142.6 0.0 2e-41 141.3 0.0 1.7 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 EER27936.1 - 0.00083 19.0 0.1 0.0015 18.2 0.1 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Ank_5 PF13857.6 EER27937.1 - 3e-10 40.1 3.6 2.6e-06 27.6 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 EER27937.1 - 6.3e-10 39.0 0.2 2.9e-09 36.9 0.2 2.2 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.30 EER27937.1 - 3.1e-09 36.9 7.3 1.2e-05 25.5 1.3 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EER27937.1 - 2.9e-08 34.2 0.0 6.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER27937.1 - 6.7e-08 32.9 0.2 4.2e-07 30.4 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER27937.1 - 5.1e-06 26.4 0.5 0.013 16.0 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Trypsin PF00089.26 EER27938.1 - 8.5e-06 25.7 0.7 3.2e-05 23.8 0.7 1.8 1 1 0 1 1 1 1 Trypsin SUI1 PF01253.22 EER27939.1 - 4.8e-22 78.3 0.5 1e-21 77.2 0.5 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EER27939.1 - 1.3e-10 41.8 0.0 2.1e-09 38.0 0.0 2.7 1 1 0 1 1 1 1 Pre-PUA-like domain Velvet PF11754.8 EER27940.1 - 4.4e-52 177.5 7.7 1.8e-32 113.2 0.0 2.9 2 2 1 3 3 3 2 Velvet factor Tropomyosin_1 PF12718.7 EER27941.1 - 1.2 9.2 7.1 0.16 12.1 1.4 2.1 2 0 0 2 2 2 0 Tropomyosin like MFS_1 PF07690.16 EER27942.1 - 8.2e-34 117.1 21.3 8.2e-34 117.1 21.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TMF_TATA_bd PF12325.8 EER27942.1 - 0.046 13.9 0.3 0.076 13.2 0.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Abhydrolase_3 PF07859.13 EER27943.1 - 1e-65 221.5 0.1 1.3e-65 221.2 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EER27943.1 - 4.4e-08 32.5 0.1 2.5e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 EER27943.1 - 9.5e-07 28.5 0.1 3.3e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EER27943.1 - 3.8e-05 22.7 0.0 9e-05 21.5 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase DHDPS PF00701.22 EER27944.1 - 3.4e-36 124.4 0.0 6.7e-36 123.5 0.0 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.6 EER27944.1 - 0.00056 19.4 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MFS18 PF17352.2 EER27944.1 - 0.031 14.7 1.6 5.3 7.5 1.7 2.4 2 0 0 2 2 2 0 Male Flower Specific protein 18 AP_endonuc_2 PF01261.24 EER27944.1 - 0.085 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Ribonuc_L-PSP PF01042.21 EER27945.1 - 5.3e-29 100.7 0.0 6.4e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP D-ser_dehydrat PF14031.6 EER27946.1 - 9.3e-26 90.3 0.0 2.5e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EER27946.1 - 2e-14 53.8 0.0 3.2e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EER27947.1 - 2.3e-36 125.3 1.5 5.5e-36 124.0 1.5 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EER27947.1 - 2.8e-17 62.7 0.0 5.2e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EER27947.1 - 8.6e-12 45.5 0.1 3.2e-11 43.6 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EER27947.1 - 1.8e-05 24.6 0.0 3.4e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_N PF02771.16 EER27947.1 - 5.5e-05 23.8 0.0 0.00012 22.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain PEP_mutase PF13714.6 EER27948.1 - 4.2e-65 219.5 0.0 4.8e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Cyclase PF04199.13 EER27949.1 - 1e-11 45.2 0.0 2.5e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 Putative cyclase AA_permease_2 PF13520.6 EER27950.1 - 7.7e-65 219.4 49.0 9.3e-65 219.1 49.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER27950.1 - 4.1e-32 111.4 44.8 5.5e-32 111.0 44.8 1.0 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 EER27950.1 - 1.6 8.8 0.0 1.6 8.8 0.0 3.9 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Peptidase_M20 PF01546.28 EER27951.1 - 4e-19 69.1 0.0 6.9e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EER27951.1 - 8e-15 54.7 0.1 1.5e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain UME PF08064.13 EER27951.1 - 0.046 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 UME (NUC010) domain UQ_con PF00179.26 EER27952.1 - 2.1e-22 79.3 0.0 3.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EER27952.1 - 0.019 14.8 0.0 0.06 13.2 0.0 1.9 1 1 0 1 1 1 0 UEV domain Rpr2 PF04032.16 EER27952.1 - 0.039 14.2 3.5 0.13 12.6 3.5 2.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain HCV_NS5a PF01506.19 EER27952.1 - 0.5 10.3 2.9 1 9.3 2.9 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor JmjC PF02373.22 EER27953.1 - 5.8e-37 126.6 1.7 2.5e-36 124.6 0.8 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H PF13771.6 EER27953.1 - 1e-18 67.3 5.7 2.4e-18 66.1 5.7 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EER27953.1 - 2.9e-18 66.0 4.3 5.5e-18 65.1 4.3 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain JmjN PF02375.17 EER27953.1 - 3.1e-13 49.4 0.5 9.2e-13 47.9 0.5 1.9 1 0 0 1 1 1 1 jmjN domain CusF_Ec PF11604.8 EER27953.1 - 0.0033 17.3 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 Copper binding periplasmic protein CusF Carn_acyltransf PF00755.20 EER27954.1 - 3.2e-211 703.0 0.0 3.9e-211 702.7 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP PF00188.26 EER27955.1 - 1.1e-15 58.5 3.3 1.6e-15 58.1 3.3 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mfp-3 PF04202.13 EER27955.1 - 1.1 9.7 6.8 0.49 10.8 0.3 2.4 2 0 0 2 2 2 0 Foot protein 3 Thioredox_DsbH PF03190.15 EER27956.1 - 1.9e-69 232.8 0.0 4.1e-69 231.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EER27956.1 - 9.3e-06 25.7 0.0 2.2e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_9 PF00759.19 EER27956.1 - 0.00075 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_88 PF07470.13 EER27956.1 - 0.046 12.8 0.0 18 4.3 0.1 3.6 3 1 0 4 4 4 0 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 EER27956.1 - 0.092 12.2 0.5 1.9 7.9 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 WD40 PF00400.32 EER27957.1 - 1.3e-19 70.2 17.8 1.9e-05 25.3 0.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER27957.1 - 0.00012 22.3 0.1 6.2 7.2 0.0 3.8 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain LSM14 PF12701.7 EER27958.1 - 2.3e-27 94.9 0.0 3.9e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EER27958.1 - 2.2e-19 70.2 4.0 5.9e-19 68.9 4.0 1.8 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 EER27958.1 - 9.7e-05 22.4 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.11 EER27958.1 - 3.9 8.2 29.6 7.7 7.3 0.6 2.8 2 0 0 2 2 2 0 Glycine rich protein family ACBP PF00887.19 EER27959.1 - 4.8e-23 81.2 0.1 4.1e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Acyl CoA binding protein SPT6_acidic PF14632.6 EER27959.1 - 0.0033 18.0 14.9 0.0084 16.7 14.9 1.7 1 0 0 1 1 1 1 Acidic N-terminal SPT6 NSP2-B_epitope PF14757.6 EER27959.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein CDC45 PF02724.14 EER27959.1 - 0.63 8.3 11.8 0.89 7.8 11.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Atg14 PF10186.9 EER27959.1 - 0.76 8.8 4.4 4 6.4 2.1 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DNA_pol_phi PF04931.13 EER27959.1 - 7.8 4.5 14.9 3.2 5.7 12.5 1.5 2 0 0 2 2 2 0 DNA polymerase phi CHCH PF06747.13 EER27960.1 - 3.4e-08 33.4 2.9 3.4e-08 33.4 2.9 2.5 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 EER27960.1 - 0.017 15.2 8.8 0.021 14.8 1.6 2.3 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 EER27960.1 - 0.1 12.9 6.8 6.9 7.1 0.1 2.9 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 EER27960.1 - 0.37 10.8 11.9 1.4 9.0 1.4 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 EER27960.1 - 1.5 9.1 10.5 3.6 7.9 1.7 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb KH_1 PF00013.29 EER27961.1 - 0.068 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 KH domain DUF5526 PF17664.1 EER27961.1 - 0.078 12.5 0.9 0.14 11.7 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5526) Prefoldin PF02996.17 EER27962.1 - 4.6e-25 87.9 1.7 5.9e-25 87.5 1.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EER27962.1 - 0.0037 17.2 2.2 0.24 11.4 0.4 2.1 2 0 0 2 2 2 2 Prefoldin subunit Tcp10_C PF07202.13 EER27962.1 - 0.057 13.4 0.1 0.077 12.9 0.1 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus BRE1 PF08647.11 EER27962.1 - 0.058 13.5 1.6 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CLZ PF16526.5 EER27962.1 - 0.097 13.0 3.7 1.9 8.9 0.3 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Mating_N PF12731.7 EER27962.1 - 0.099 12.7 0.1 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Mating-type protein beta 1 tRNA-synt_2b PF00587.25 EER27963.1 - 1.9e-29 102.9 0.0 1.1e-28 100.5 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EER27963.1 - 3.7e-07 30.2 0.1 1.6e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain CBF PF03914.17 EER27964.1 - 1.2e-54 184.9 1.9 1.7e-54 184.4 0.2 2.3 2 0 0 2 2 2 1 CBF/Mak21 family DUF2533 PF10752.9 EER27964.1 - 0.067 13.6 0.1 0.2 12.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) Cnd1 PF12717.7 EER27964.1 - 0.08 13.0 0.4 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 LANC_like PF05147.13 EER27965.1 - 1.1e-24 86.7 0.2 5.3e-23 81.2 0.2 2.3 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein TPR_12 PF13424.6 EER27966.1 - 0.01 16.1 1.0 0.051 13.9 0.0 2.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EER27966.1 - 0.017 15.2 0.0 0.13 12.4 0.0 2.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC5 PF12862.7 EER27966.1 - 0.018 15.1 0.1 0.077 13.1 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_7 PF13176.6 EER27966.1 - 0.055 13.5 0.0 0.37 10.9 0.0 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_4 PF07721.14 EER27966.1 - 0.083 13.6 0.1 0.32 11.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 EER27966.1 - 0.092 12.6 0.3 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat QRPTase_N PF02749.16 EER27966.1 - 0.093 12.8 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain Aa_trans PF01490.18 EER27967.1 - 1.1e-23 83.6 33.2 4.9e-23 81.5 33.2 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1218 PF06749.12 EER27967.1 - 0.82 10.2 0.0 0.82 10.2 0.0 4.1 4 1 1 5 5 5 0 Protein of unknown function (DUF1218) DUF3671 PF12420.8 EER27967.1 - 7.1 6.7 5.8 23 5.1 1.5 3.0 2 0 0 2 2 2 0 Protein of unknown function GCV_T PF01571.21 EER27968.1 - 1.9e-79 266.7 0.0 2.5e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EER27968.1 - 1.8e-15 56.6 0.0 6.9e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain APS_kinase PF01583.20 EER27969.1 - 1.1e-69 233.4 0.0 1.4e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EER27969.1 - 6.2e-05 23.2 0.0 0.00013 22.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EER27969.1 - 0.0005 20.6 0.0 0.0012 19.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 EER27969.1 - 0.0047 16.4 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.6 EER27969.1 - 0.0093 16.4 0.0 0.013 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EER27969.1 - 0.034 13.4 0.0 0.064 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Sigma54_CBD PF04963.13 EER27969.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain V-ATPase_C PF03223.15 EER27970.1 - 1.1e-124 416.6 0.0 1.3e-124 416.4 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C 4HBT PF03061.22 EER27971.1 - 2.2e-11 43.9 0.0 3.8e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ligase_CoA PF00549.19 EER27972.1 - 7e-35 120.1 1.7 7.2e-18 64.9 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EER27972.1 - 1.4e-13 51.3 1.0 2e-12 47.6 0.4 2.8 3 0 0 3 3 3 1 CoA binding domain Succ_CoA_lig PF13607.6 EER27972.1 - 1.3e-08 34.7 0.2 2e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EER27972.1 - 0.0046 17.4 0.5 0.016 15.7 0.2 2.1 2 0 0 2 2 2 1 CoA binding domain Rad60-SLD PF11976.8 EER27974.1 - 6e-20 70.8 0.3 7.3e-20 70.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EER27974.1 - 1.3e-10 40.9 0.1 1.4e-10 40.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Nup84_Nup100 PF04121.13 EER27975.1 - 1.2e-154 516.3 1.8 2e-154 515.5 1.8 1.4 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Cation_ATPase_C PF00689.21 EER27976.1 - 6.8e-47 159.5 6.5 6.8e-47 159.5 6.5 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EER27976.1 - 1.7e-35 122.2 0.3 1.7e-35 122.2 0.3 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EER27976.1 - 5.6e-23 80.8 0.0 1.1e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EER27976.1 - 3.4e-19 70.0 0.1 1.3e-18 68.1 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EER27976.1 - 2.1e-05 24.4 0.8 0.00011 22.1 0.4 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EER27976.1 - 2.7e-05 23.8 0.2 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus RskA PF10099.9 EER27976.1 - 0.042 14.1 0.7 18 5.5 0.1 3.2 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF2236 PF09995.9 EER27977.1 - 3.2e-08 34.1 0.0 5.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) NTase_sub_bind PF08780.11 EER27977.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like Aldedh PF00171.22 EER27978.1 - 4e-109 365.2 0.1 5.1e-109 364.8 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.25 EER27979.1 - 1.2e-67 228.0 0.0 2.3e-67 227.0 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EER27979.1 - 4.7e-42 143.1 0.0 7.4e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EER27979.1 - 6.8e-05 23.2 0.0 0.00018 21.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EER27979.1 - 0.00084 18.6 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EER27979.1 - 0.0048 16.6 0.0 0.0089 15.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 EER27980.1 - 1.5e-15 56.7 0.1 3.1e-07 30.1 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EER27980.1 - 1.1 9.3 10.9 0.1 12.7 0.5 3.4 3 1 0 3 3 3 0 RNA binding motif Ammonium_transp PF00909.21 EER27981.1 - 8.5e-98 327.6 22.0 2.1e-50 171.6 2.9 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family Pkinase PF00069.25 EER27982.1 - 2.1e-65 220.7 0.0 3.6e-65 219.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER27982.1 - 9.7e-34 116.8 0.0 6.4e-32 110.9 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER27982.1 - 9e-06 25.8 0.7 0.0029 17.6 0.1 2.9 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EER27982.1 - 1.8e-05 23.7 0.1 3.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EER27982.1 - 2.1e-05 24.0 0.6 0.00058 19.3 0.6 2.3 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EER27982.1 - 0.0061 15.7 0.1 0.014 14.4 0.1 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 EER27982.1 - 0.05 13.2 0.2 0.11 12.1 0.2 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EER27982.1 - 0.14 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Vac_ImportDeg PF09783.9 EER27983.1 - 3.3e-68 228.6 2.1 4.1e-68 228.3 2.1 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 EER27984.1 - 3.2e-71 238.0 0.4 4e-71 237.7 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 EER27985.1 - 4.7e-94 315.8 8.7 8.1e-94 315.0 8.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EER27985.1 - 1.2e-57 193.8 0.4 2.7e-57 192.6 0.4 1.7 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EER27985.1 - 1.3e-55 186.8 0.0 3.8e-55 185.3 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EER27985.1 - 2.7e-13 50.3 3.9 1e-08 35.4 0.0 3.0 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EER27985.1 - 1.2e-09 38.4 7.5 0.00048 20.5 0.0 5.4 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.22 EER27985.1 - 0.00045 20.2 0.4 5 7.6 0.1 5.0 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 EER27985.1 - 0.00092 19.3 0.0 0.0081 16.3 0.0 2.6 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform AP4E_app_platf PF14807.6 EER27985.1 - 0.064 13.6 0.1 0.24 11.8 0.1 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 EER27985.1 - 0.075 13.6 1.3 19 5.9 0.1 4.4 3 1 1 4 4 4 0 HEAT-like repeat DUF5578 PF17741.1 EER27985.1 - 0.17 11.3 3.1 1.5 8.2 0.2 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5578) RhoGAP PF00620.27 EER27985.1 - 0.42 10.4 2.3 2.1 8.1 0.1 3.2 3 1 0 3 3 3 0 RhoGAP domain PAPA-1 PF04795.12 EER27985.1 - 1.4 9.7 4.0 0.8 10.6 0.5 2.4 3 0 0 3 3 1 0 PAPA-1-like conserved region DAGK_cat PF00781.24 EER27986.1 - 1.1e-26 93.0 0.0 1.6e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GIT_SHD PF08518.11 EER27986.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT Nop52 PF05997.12 EER27987.1 - 1.3e-52 178.8 0.8 2.7e-52 177.7 0.8 1.4 1 1 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.8 EER27987.1 - 0.018 15.2 0.3 0.08 13.1 0.3 2.1 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair HEAT PF02985.22 EER27987.1 - 0.15 12.4 0.0 16 6.1 0.0 2.7 2 0 0 2 2 2 0 HEAT repeat UBD PF16455.5 EER27988.1 - 6.5e-42 142.0 0.0 9.7e-42 141.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 EER27988.1 - 0.00041 20.0 0.2 0.00086 19.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 EER27988.1 - 0.0064 17.0 0.4 0.049 14.2 0.0 2.2 1 1 1 2 2 2 1 DUF2407 ubiquitin-like domain TPR_4 PF07721.14 EER27988.1 - 0.032 14.9 0.4 1 10.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Corona_nucleoca PF00937.18 EER27988.1 - 0.077 12.0 1.3 0.13 11.3 1.3 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF4050 PF13259.6 EER27988.1 - 0.92 9.8 4.3 1.7 8.9 4.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) DUF1604 PF07713.13 EER27989.1 - 2.9e-41 139.2 4.5 3.9e-41 138.8 0.8 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EER27989.1 - 1.6e-07 31.1 0.4 4.1e-07 29.8 0.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EER27989.1 - 0.0018 18.3 0.2 0.0082 16.2 0.1 2.3 2 0 0 2 2 2 1 G-patch domain Pkinase PF00069.25 EER27990.1 - 4.9e-69 232.6 0.1 2e-64 217.5 0.0 2.2 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER27990.1 - 7.3e-39 133.6 0.0 2.5e-38 131.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EER27990.1 - 6.5e-17 61.1 0.4 1.3e-16 60.1 0.4 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 EER27990.1 - 4.5e-06 25.9 0.1 7.3e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EER27990.1 - 6.1e-06 25.8 0.0 4.5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EER27990.1 - 0.00012 21.5 0.1 0.00021 20.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 EER27990.1 - 0.0055 16.4 0.1 0.0093 15.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 EER27990.1 - 0.0074 16.2 0.0 0.2 11.6 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EER27990.1 - 0.04 13.5 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EER27990.1 - 0.073 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SET PF00856.28 EER27991.1 - 1.4e-18 67.8 0.6 3.8e-18 66.5 0.0 2.0 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 EER27991.1 - 1.6e-09 38.4 8.6 1.6e-09 38.4 8.6 2.4 2 1 0 2 2 2 1 Pre-SET motif APH PF01636.23 EER27992.1 - 5.8e-11 42.8 0.1 2.2e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 EER27992.1 - 0.0027 17.1 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Prok-E2_A PF14457.6 EER27993.1 - 0.14 11.8 0.4 0.25 10.9 0.4 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family A APH PF01636.23 EER27994.1 - 2.4e-14 53.8 0.0 9.1e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER27994.1 - 4.1e-09 36.4 0.0 5.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EER27994.1 - 0.049 12.5 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ion_trans PF00520.31 EER27996.1 - 6.4e-124 412.0 83.8 1.9e-41 141.9 3.5 4.7 4 1 0 4 4 4 4 Ion transport protein GPHH PF16905.5 EER27996.1 - 0.00075 19.2 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 EER27996.1 - 0.0011 18.3 0.0 0.0038 16.7 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EER27996.1 - 0.018 14.9 0.0 0.11 12.5 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EER27996.1 - 0.066 13.7 0.2 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair Proteasom_Rpn13 PF04683.13 EER27997.1 - 8.8e-26 90.3 0.0 1.4e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EER27997.1 - 5.7e-11 42.6 4.3 9.4e-09 35.4 3.0 3.0 2 1 0 2 2 2 1 UCH-binding domain Ribosomal_L6e PF01159.19 EER27998.1 - 1.1e-39 135.4 0.1 1.6e-39 134.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e DUF2476 PF10630.9 EER27998.1 - 0.033 14.4 2.0 3 7.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2476) FA_hydroxylase PF04116.13 EER27999.1 - 4.9e-16 59.3 4.3 4.9e-16 59.3 4.3 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily TMEM237 PF15383.6 EER27999.1 - 0.11 11.6 0.1 6.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 237 adh_short PF00106.25 EER28001.1 - 2.4e-23 82.6 0.0 3.3e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER28001.1 - 1.5e-11 44.3 0.0 2.7e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER28001.1 - 1.5e-08 34.8 0.2 9.5e-08 32.2 0.2 2.0 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EER28001.1 - 0.0014 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 EER28001.1 - 0.0019 18.3 0.3 0.0073 16.4 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EER28001.1 - 0.0032 17.9 0.1 0.0069 16.8 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding F420_oxidored PF03807.17 EER28001.1 - 0.0053 17.3 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 EER28001.1 - 0.0063 15.9 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Sacchrp_dh_NADP PF03435.18 EER28001.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EER28001.1 - 0.014 15.3 0.1 0.03 14.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EER28001.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EER28001.1 - 0.024 14.8 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.15 EER28001.1 - 0.062 12.4 0.3 0.17 11.0 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Sas10 PF09368.10 EER28002.1 - 4.8e-29 100.6 5.8 4.8e-29 100.6 5.8 3.2 4 0 0 4 4 4 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EER28002.1 - 2.4e-12 47.3 0.5 2.6e-11 44.0 0.1 2.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family MutS_V PF00488.21 EER28003.1 - 5.5e-40 137.4 0.6 1.2e-37 129.8 0.2 3.1 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EER28003.1 - 4.4e-16 59.7 0.2 1.9e-15 57.6 0.0 2.0 2 0 0 2 2 2 1 MutS domain III ATP-grasp_4 PF13535.6 EER28003.1 - 0.0045 16.6 0.1 0.33 10.5 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain MutS_IV PF05190.18 EER28003.1 - 0.0065 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA PF00004.29 EER28003.1 - 0.086 13.3 0.1 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EER28004.1 - 5.8e-47 160.0 0.0 3.9e-45 154.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EER28004.1 - 1.6e-35 121.1 1.3 1.6e-35 121.1 1.3 2.5 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EER28004.1 - 5.7e-26 90.4 0.1 1.9e-25 88.7 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EER28004.1 - 1.4e-18 67.6 0.1 2.6e-09 37.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EER28004.1 - 7.6e-13 48.6 2.6 5.2e-08 33.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EER28004.1 - 5.3e-11 43.2 3.1 0.0001 22.7 0.2 4.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EER28004.1 - 1.2e-07 32.1 1.2 0.026 14.8 0.0 3.6 3 2 0 3 3 2 2 AAA domain Sigma54_activat PF00158.26 EER28004.1 - 5.1e-07 29.5 0.6 0.00044 20.0 0.0 2.6 2 1 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.17 EER28004.1 - 1.3e-05 25.0 0.0 0.077 12.7 0.1 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EER28004.1 - 1.7e-05 24.4 0.0 0.033 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 EER28004.1 - 3.4e-05 23.8 0.1 0.24 11.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_14 PF13173.6 EER28004.1 - 3.6e-05 23.8 0.0 0.41 10.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EER28004.1 - 3.8e-05 23.2 0.0 0.045 13.2 0.0 3.5 3 1 0 3 3 2 1 Bacterial TniB protein AAA_28 PF13521.6 EER28004.1 - 9.6e-05 22.7 0.7 0.052 13.8 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.6 EER28004.1 - 0.00026 21.5 0.2 0.89 10.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 EER28004.1 - 0.00028 20.9 4.7 1.5 8.7 0.0 4.0 3 2 0 3 3 2 1 ATPase domain predominantly from Archaea SRP54 PF00448.22 EER28004.1 - 0.00038 20.2 0.1 0.066 12.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EER28004.1 - 0.00063 19.5 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EER28004.1 - 0.0018 18.6 0.0 0.82 10.1 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_19 PF13245.6 EER28004.1 - 0.0021 18.4 1.1 0.1 12.9 0.2 3.1 2 2 0 2 2 2 1 AAA domain ResIII PF04851.15 EER28004.1 - 0.003 17.6 0.1 4.7 7.2 0.0 3.2 2 1 0 3 3 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EER28004.1 - 0.0038 17.2 0.1 3 7.9 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EER28004.1 - 0.0054 16.9 0.0 3.1 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EER28004.1 - 0.0077 15.6 0.2 3.3 7.0 0.0 3.1 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 EER28004.1 - 0.01 14.8 0.0 0.33 9.8 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PduV-EutP PF10662.9 EER28004.1 - 0.013 15.2 0.0 0.51 10.1 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EER28004.1 - 0.016 15.1 0.0 3.7 7.4 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 EER28004.1 - 0.016 15.4 0.0 1.3 9.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF853 PF05872.12 EER28004.1 - 0.022 13.4 0.2 0.2 10.2 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Zeta_toxin PF06414.12 EER28004.1 - 0.026 13.8 0.0 2.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 EER28004.1 - 0.034 13.9 0.1 0.52 10.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EER28004.1 - 0.036 13.8 6.1 0.13 12.0 0.5 3.8 4 1 0 4 4 2 0 AAA domain UvrD-helicase PF00580.21 EER28004.1 - 0.041 13.4 2.9 0.26 10.7 0.1 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_25 PF13481.6 EER28004.1 - 0.041 13.5 0.2 0.6 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EER28004.1 - 0.046 13.6 0.0 0.53 10.2 0.0 2.5 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 EER28004.1 - 0.05 14.1 1.8 3 8.4 0.0 3.2 3 0 0 3 3 3 0 ABC transporter DUF815 PF05673.13 EER28004.1 - 0.057 12.6 0.2 1.1 8.4 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_6 PF12774.7 EER28004.1 - 0.13 11.2 0.1 4.2 6.2 0.0 2.5 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region AAA_21 PF13304.6 EER28004.1 - 0.18 11.6 1.3 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Rootletin PF15035.6 EER28004.1 - 0.44 10.5 9.1 0.85 9.6 9.1 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4094 PF13334.6 EER28004.1 - 0.78 10.2 4.1 0.52 10.8 0.6 2.5 3 0 0 3 3 1 0 Domain of unknown function (DUF4094) UPF0242 PF06785.11 EER28004.1 - 1.9 8.6 10.1 3.9 7.5 10.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5401 PF17380.2 EER28004.1 - 3.2 5.7 9.8 4.7 5.2 9.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Atg14 PF10186.9 EER28004.1 - 4.5 6.3 5.4 8.2 5.4 5.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EF1_GNE PF00736.19 EER28005.1 - 1.4e-32 111.7 2.4 2.3e-32 111.0 2.4 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EER28005.1 - 4.5e-12 46.2 3.9 4.5e-12 46.2 3.9 2.0 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 EER28005.1 - 0.0069 16.6 1.5 0.012 15.8 0.1 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cucumopine_C PF18631.1 EER28005.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Cucumopine synthase C-terminal helical bundle domain GST_C_3 PF14497.6 EER28005.1 - 0.038 14.2 0.4 0.072 13.3 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain MMgT PF10270.9 EER28006.1 - 7.1e-26 90.5 0.0 8e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter DUF1180 PF06679.12 EER28007.1 - 0.16 12.4 2.5 0.17 12.3 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) UQ_con PF00179.26 EER28008.1 - 4e-35 120.5 0.0 7.4e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER28008.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EER28008.1 - 0.046 14.0 0.1 0.67 10.3 0.0 2.3 2 0 0 2 2 2 0 RWD domain RNB PF00773.19 EER28009.1 - 3.4e-84 283.0 0.0 6.3e-84 282.1 0.0 1.5 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 EER28009.1 - 4.9e-26 90.5 0.1 2.1e-25 88.5 0.0 2.2 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EER28009.1 - 1.4e-25 89.4 0.0 4.4e-25 87.8 0.0 1.9 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EER28009.1 - 1.4e-05 25.2 0.0 0.0081 16.3 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EER28009.1 - 5.5e-05 22.9 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain NPR3 PF03666.13 EER28009.1 - 2.1 7.1 7.0 0.34 9.6 0.2 2.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 GLE1 PF07817.13 EER28010.1 - 1.6e-50 171.7 0.0 4.7e-50 170.1 0.0 1.7 2 0 0 2 2 2 1 GLE1-like protein Glyco_hydro_17 PF00332.18 EER28012.1 - 5.7e-37 128.0 1.5 5e-36 124.9 1.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 EMP24_GP25L PF01105.24 EER28013.1 - 5.8e-47 160.0 0.2 6.7e-47 159.8 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DNase_NucA_NucB PF14040.6 EER28013.1 - 0.072 13.5 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB Big_11 PF18200.1 EER28013.1 - 0.074 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain DUF4793 PF16041.5 EER28013.1 - 0.16 12.2 0.1 0.35 11.1 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4793) DUF3237 PF11578.8 EER28014.1 - 2.5e-33 115.0 0.0 2.9e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) 14-3-3 PF00244.20 EER28016.1 - 1.6e-08 34.3 0.4 2.5e-08 33.7 0.1 1.4 2 0 0 2 2 2 1 14-3-3 protein Acyl-CoA_dh_1 PF00441.24 EER28017.1 - 1.3e-30 106.6 0.3 2e-30 106.0 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EER28017.1 - 4.8e-23 81.2 0.1 9.1e-23 80.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EER28017.1 - 5.2e-15 56.1 0.1 6.8e-14 52.5 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EER28017.1 - 0.00015 22.1 0.1 0.00024 21.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 EER28018.1 - 1.2e-15 57.3 26.8 8.7e-08 32.2 11.0 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EER28018.1 - 3.8e-15 55.6 0.0 7.9e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.14 EER28019.1 - 1.4e-36 125.8 0.0 1.8e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.21 EER28019.1 - 0.14 11.0 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain CHORD PF04968.12 EER28020.1 - 6.6e-51 170.9 19.8 1.5e-27 96.1 5.8 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 EER28020.1 - 3e-14 53.8 0.1 4.7e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 EER28020.1 - 0.62 9.9 11.7 2.7 7.9 0.3 3.0 3 0 0 3 3 3 0 BTK motif Choline_kinase PF01633.20 EER28021.1 - 3.8e-47 160.6 0.0 2.9e-46 157.7 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EER28021.1 - 1.5e-09 38.1 0.3 1.5e-09 38.1 0.3 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EER28021.1 - 0.019 14.3 0.0 0.61 9.3 0.0 2.2 2 0 0 2 2 2 0 Ecdysteroid kinase Sod_Cu PF00080.20 EER28022.1 - 4e-08 33.5 0.0 5.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3405 PF11885.8 EER28023.1 - 2.2e-228 759.0 0.1 2.6e-228 758.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF5438 PF17506.2 EER28024.1 - 0.033 14.5 2.0 0.071 13.4 2.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5438) Arf PF00025.21 EER28025.1 - 5.7e-79 263.6 0.2 6.8e-79 263.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EER28025.1 - 3.7e-15 55.8 0.0 4.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EER28025.1 - 2.5e-14 53.5 0.0 3.6e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EER28025.1 - 1.3e-13 50.8 1.3 1.5e-09 37.5 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EER28025.1 - 3.9e-13 49.3 0.0 4.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EER28025.1 - 2.1e-10 40.4 0.0 2.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EER28025.1 - 5.3e-06 26.5 0.0 7.8e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EER28025.1 - 0.0084 15.4 0.4 0.017 14.4 0.4 1.6 1 1 0 1 1 1 1 6-phosphofructo-2-kinase CorA PF01544.18 EER28026.1 - 5.6e-05 22.6 0.5 0.013 14.8 0.1 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Bee_toxin PF17454.2 EER28026.1 - 0.11 12.6 0.2 0.31 11.1 0.2 1.8 1 0 0 1 1 1 0 Honey bee toxin Acetyltransf_7 PF13508.7 EER28027.1 - 9.1e-10 38.8 0.0 1.5e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER28027.1 - 4.2e-08 33.4 0.0 5.4e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER28027.1 - 1.3e-06 28.4 0.0 4.4e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER28027.1 - 1.6e-05 24.8 0.0 5.3e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Ribosomal_L1 PF00687.21 EER28028.1 - 9.9e-48 162.6 0.2 1.1e-47 162.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF364 PF04016.12 EER28029.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative heavy-metal chelation WH2 PF02205.20 EER28030.1 - 3.7e-09 36.1 0.7 1e-08 34.7 0.7 1.8 1 0 0 1 1 1 1 WH2 motif LSM PF01423.22 EER28031.1 - 2.7e-17 62.2 0.0 3.7e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain SURF4 PF02077.15 EER28033.1 - 8.2e-97 324.0 6.7 9.3e-97 323.8 6.7 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 EER28033.1 - 0.016 15.2 12.2 0.023 14.7 12.2 1.3 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter DoxX PF07681.12 EER28033.1 - 2.8 8.6 22.0 0.37 11.4 0.8 3.4 3 2 0 3 3 3 0 DoxX IU_nuc_hydro PF01156.19 EER28035.1 - 5e-60 203.6 0.0 1e-59 202.7 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HLH PF00010.26 EER28036.1 - 2.8e-14 52.8 0.9 5.7e-14 51.8 0.9 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4200 PF13863.6 EER28036.1 - 0.17 12.3 0.2 0.27 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) FERM_M PF00373.18 EER28036.1 - 0.17 12.3 0.0 0.17 12.3 0.0 1.6 2 0 0 2 2 2 0 FERM central domain Suf PF05843.14 EER28037.1 - 0.3 11.1 9.9 0.49 10.3 9.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NOA36 PF06524.12 EER28037.1 - 0.97 8.7 9.3 1.6 8.0 9.3 1.3 1 0 0 1 1 1 0 NOA36 protein Hamartin PF04388.12 EER28037.1 - 1.3 7.6 13.6 1.5 7.4 13.6 1.1 1 0 0 1 1 1 0 Hamartin protein DUF4611 PF15387.6 EER28037.1 - 1.5 9.1 10.2 0.047 13.9 3.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DNA_pol_phi PF04931.13 EER28037.1 - 1.9 6.5 5.3 2.5 6.1 5.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 EER28038.1 - 2.3e-33 115.6 26.9 2.3e-33 115.6 26.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4017 PF13209.6 EER28038.1 - 0.016 15.1 5.3 0.31 11.0 1.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) FixQ PF05545.11 EER28038.1 - 0.61 10.1 0.0 0.61 10.1 0.0 4.0 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Aa_trans PF01490.18 EER28039.1 - 6e-23 81.2 26.3 2.3e-15 56.3 17.3 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein TctB PF07331.11 EER28039.1 - 0.1 12.8 0.1 0.1 12.8 0.1 4.6 4 1 0 4 4 4 0 Tripartite tricarboxylate transporter TctB family TMEM214 PF10151.9 EER28039.1 - 0.8 8.1 3.9 1.2 7.5 3.9 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator p450 PF00067.22 EER28040.1 - 3.9e-60 203.9 0.0 4.4e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EER28041.1 - 7.9e-20 71.0 0.1 1.5e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28041.1 - 2.6e-08 33.8 8.9 7.8e-08 32.3 8.9 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leu_zip PF15294.6 EER28042.1 - 0.012 15.2 22.9 0.027 14.0 22.9 1.6 1 0 0 1 1 1 0 Leucine zipper GMP_synt_C PF00958.22 EER28042.1 - 0.031 14.3 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 GMP synthase C terminal domain Prominin PF05478.11 EER28042.1 - 0.2 9.6 7.6 0.29 9.0 7.6 1.3 1 0 0 1 1 1 0 Prominin DUF3037 PF11236.8 EER28042.1 - 2.3 8.7 6.6 1.5 9.3 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) DUF3450 PF11932.8 EER28042.1 - 3.2 7.0 16.0 8 5.7 16.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) KELK PF15796.5 EER28042.1 - 3.9 8.0 32.3 2.8 8.5 12.3 3.9 1 1 2 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GAS PF13851.6 EER28042.1 - 4.3 6.6 33.2 2.8 7.2 30.8 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding HSP70 PF00012.20 EER28042.1 - 6.7 4.8 19.1 11 4.1 19.1 1.3 1 0 0 1 1 1 0 Hsp70 protein Peptidase_S8 PF00082.22 EER28043.1 - 9.4e-32 110.5 8.9 1.8e-31 109.5 8.9 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER28043.1 - 3.4e-14 53.3 0.0 5.5e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_M14 PF00246.24 EER28044.1 - 3e-80 270.1 0.5 3.9e-80 269.8 0.5 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 EER28044.1 - 6.6e-10 39.2 0.2 2.6e-09 37.4 0.0 2.1 3 0 0 3 3 3 1 Carboxypeptidase activation peptide IL11 PF07400.11 EER28044.1 - 0.2 11.3 0.3 0.36 10.5 0.3 1.4 1 0 0 1 1 1 0 Interleukin 11 Fungal_trans PF04082.18 EER28045.1 - 7.9e-17 61.2 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rox3 PF08633.10 EER28046.1 - 1.2e-69 234.7 0.1 1.2e-69 234.7 0.1 1.7 2 0 0 2 2 2 1 Rox3 mediator complex subunit Hydrolase PF00702.26 EER28047.1 - 7.3e-07 29.7 0.0 9.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EER28047.1 - 8.6e-07 29.2 0.0 2.1e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER28047.1 - 0.15 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4202 PF13875.6 EER28048.1 - 3.4e-81 271.6 0.1 3.9e-81 271.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) IL12 PF03039.14 EER28048.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Interleukin-12 alpha subunit VIT1 PF01988.19 EER28049.1 - 3.4e-62 210.1 2.4 4.1e-62 209.9 2.4 1.1 1 0 0 1 1 1 1 VIT family PAH PF02671.21 EER28049.1 - 0.091 12.9 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Paired amphipathic helix repeat LSM PF01423.22 EER28050.1 - 6.5e-19 67.4 0.1 7.2e-19 67.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EER28050.1 - 0.0024 18.0 0.1 0.0027 17.8 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EER28050.1 - 0.0069 16.5 0.1 0.0079 16.3 0.1 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain VPS9 PF02204.18 EER28052.1 - 2.2e-30 104.9 0.0 3.9e-30 104.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EER28052.1 - 2.1e-14 53.5 0.1 5.1e-14 52.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EER28052.1 - 2.3e-09 36.8 0.1 2.2e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 CUE domain DUF572 PF04502.13 EER28052.1 - 9.8 5.7 13.6 41 3.6 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Asn_synthase PF00733.21 EER28053.1 - 1.2e-14 54.7 0.1 0.00056 19.7 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EER28053.1 - 2.4e-05 24.2 0.0 0.00019 21.3 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain PH_6 PF15406.6 EER28054.1 - 5.4e-33 113.6 2.7 5.4e-33 113.6 2.7 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EER28054.1 - 4.3e-05 24.0 0.0 0.00018 22.0 0.0 2.1 1 0 0 1 1 1 1 PH domain Sulfate_transp PF00916.20 EER28055.1 - 1.4e-60 205.0 19.0 2.2e-60 204.4 19.0 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EER28055.1 - 8.1e-15 54.7 0.0 1.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EER28055.1 - 4.1e-10 39.3 0.1 7.4e-10 38.5 0.1 1.4 1 0 0 1 1 1 1 STAS domain DUF3180 PF11377.8 EER28055.1 - 1.5 9.0 14.2 1.9 8.6 6.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3180) Sld5 PF05916.11 EER28056.1 - 4.7e-09 36.7 0.0 6.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.19 EER28057.1 - 8.5e-10 38.9 0.6 3e-09 37.2 0.6 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box PHD PF00628.29 EER28058.1 - 3.2e-09 36.5 10.6 7.2e-09 35.4 10.6 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EER28058.1 - 0.31 10.6 10.1 0.021 14.4 4.8 1.8 2 0 0 2 2 2 0 PHD-finger zf-RING_9 PF13901.6 EER28058.1 - 1.3 9.0 12.3 2.1 8.3 12.3 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon C1_2 PF03107.16 EER28058.1 - 3.8 7.9 6.2 0.9 9.9 2.0 2.0 2 0 0 2 2 2 0 C1 domain PNTB PF02233.16 EER28059.1 - 7.1e-176 585.6 25.8 7.1e-176 585.6 25.8 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EER28059.1 - 2.9e-73 245.7 0.4 8.2e-73 244.2 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EER28059.1 - 6.5e-42 143.1 0.0 2e-41 141.5 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EER28059.1 - 7.8e-30 103.2 3.6 7.8e-30 103.2 3.6 5.0 4 2 2 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EER28059.1 - 0.0014 18.0 0.5 1.7 8.0 0.1 3.6 4 0 0 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EER28059.1 - 0.03 13.5 0.1 0.082 12.1 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EER28059.1 - 0.082 12.0 0.6 0.15 11.1 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EER28059.1 - 9.5 6.5 8.2 1.2 9.4 2.2 2.8 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain bZIP_2 PF07716.15 EER28060.1 - 6.8e-05 22.9 9.5 0.00011 22.2 9.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EER28060.1 - 0.00013 22.0 8.4 0.00024 21.1 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor Baculo_11_kDa PF06143.11 EER28060.1 - 0.16 11.6 0.1 0.34 10.5 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Rcd1 PF04078.13 EER28061.1 - 9.4e-126 418.4 3.4 1.2e-125 418.0 3.4 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TFIIA PF03153.13 EER28061.1 - 0.12 12.3 31.8 0.16 12.0 31.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EER28061.1 - 0.83 7.8 21.5 0.95 7.7 21.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Otopetrin PF03189.13 EER28061.1 - 2.1 7.1 7.9 0.12 11.2 1.3 1.8 2 0 0 2 2 2 0 Otopetrin DUF4690 PF15756.5 EER28062.1 - 0.00014 22.4 0.6 0.00035 21.1 0.6 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage CYYR1 PF10873.8 EER28062.1 - 0.0063 17.0 1.7 0.0063 17.0 1.7 2.9 3 1 0 3 3 3 1 Cysteine and tyrosine-rich protein 1 F-box-like PF12937.7 EER28063.1 - 1.6e-07 31.1 0.3 6.3e-07 29.2 0.3 2.1 1 0 0 1 1 1 1 F-box-like DIOX_N PF14226.6 EER28065.1 - 1.7e-29 102.9 0.0 3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EER28065.1 - 1.5e-14 54.3 0.0 2.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 EER28066.1 - 8e-24 84.1 1.4 1.3e-23 83.4 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28066.1 - 0.00014 21.9 11.8 0.00031 20.8 11.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.28 EER28067.1 - 1.3e-70 238.8 0.0 3.7e-69 233.9 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EER28067.1 - 2.3e-10 40.7 0.2 5.4e-10 39.5 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EER28067.1 - 0.0076 15.2 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Transp_cyt_pur PF02133.15 EER28068.1 - 7.7e-26 90.9 32.6 1.4e-24 86.7 32.6 2.2 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Abhydrolase_6 PF12697.7 EER28069.1 - 1.5e-15 58.4 0.4 1.9e-15 58.1 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER28069.1 - 7.9e-14 51.9 0.0 1e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.12 EER28069.1 - 0.00015 20.9 0.0 0.00021 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.8 EER28069.1 - 0.00029 20.2 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EER28069.1 - 0.0012 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase AXE1 PF05448.12 EER28069.1 - 0.042 12.5 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DNase_NucA_NucB PF14040.6 EER28070.1 - 2.3e-47 160.1 2.0 4.1e-47 159.3 2.0 1.4 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB FAD_binding_3 PF01494.19 EER28072.1 - 2e-11 43.8 0.1 0.00053 19.3 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EER28072.1 - 0.00027 21.1 0.1 0.00052 20.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EER28072.1 - 0.0021 18.6 0.1 0.15 12.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER28072.1 - 0.011 15.0 0.3 0.091 12.0 0.3 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EER28072.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EER28072.1 - 0.061 12.6 0.1 0.39 9.9 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BNIP3 PF06553.12 EER28073.1 - 0.17 11.6 1.9 0.27 10.9 1.9 1.3 1 0 0 1 1 1 0 BNIP3 Mito_carr PF00153.27 EER28074.1 - 3.5e-54 180.7 1.5 2.3e-19 69.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prefoldin_2 PF01920.20 EER28076.1 - 3.3e-20 72.0 3.8 4e-20 71.8 3.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Dynamitin PF04912.14 EER28076.1 - 0.0093 15.3 1.6 0.012 15.0 1.6 1.1 1 0 0 1 1 1 1 Dynamitin Rootletin PF15035.6 EER28076.1 - 0.013 15.5 1.2 0.033 14.2 0.1 1.8 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF241 PF03087.14 EER28076.1 - 0.027 14.3 1.0 0.038 13.8 1.0 1.4 1 1 0 1 1 1 0 Arabidopsis protein of unknown function SseC PF04888.12 EER28076.1 - 0.029 14.0 0.7 0.036 13.7 0.7 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family CCDC-167 PF15188.6 EER28076.1 - 0.038 14.3 0.2 0.066 13.6 0.2 1.5 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 Baculo_PEP_C PF04513.12 EER28076.1 - 0.041 13.9 1.3 0.19 11.8 0.1 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.6 EER28076.1 - 0.062 12.7 3.6 1.6 8.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF4407 PF14362.6 EER28076.1 - 0.069 12.5 0.3 0.091 12.1 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5082 PF16888.5 EER28076.1 - 0.079 13.2 5.7 0.36 11.1 5.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) CLZ PF16526.5 EER28076.1 - 0.11 12.9 1.6 0.19 12.1 0.1 1.9 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF3450 PF11932.8 EER28076.1 - 0.13 11.6 3.9 3.4 6.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CC2-LZ PF16516.5 EER28076.1 - 0.18 12.2 3.6 4 7.9 0.2 2.1 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Fib_alpha PF08702.10 EER28076.1 - 0.18 12.0 5.9 0.36 11.0 0.2 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EER28076.1 - 0.2 12.0 3.8 0.38 11.1 0.3 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EER28076.1 - 0.21 11.6 5.1 0.24 11.4 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 EER28076.1 - 0.22 11.6 3.2 1.4 9.1 0.2 2.1 2 0 0 2 2 2 0 Tropomyosin like CtIP_N PF10482.9 EER28076.1 - 0.29 11.2 5.7 3.2 7.8 0.4 2.3 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ADIP PF11559.8 EER28076.1 - 0.42 10.7 7.0 4.5 7.3 1.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 EER28076.1 - 0.94 10.1 5.7 5.5 7.7 0.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA Prefoldin PF02996.17 EER28076.1 - 1 9.3 5.6 0.93 9.4 0.2 2.1 1 1 0 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 EER28076.1 - 1.3 9.5 0.1 1.3 9.5 0.1 2.6 3 1 0 3 3 2 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 EER28076.1 - 2.9 8.6 6.0 19 5.9 0.1 2.3 2 0 0 2 2 2 0 SlyX Ceramidase PF05875.12 EER28077.1 - 2.8e-104 348.2 12.1 3.3e-104 348.0 12.1 1.0 1 0 0 1 1 1 1 Ceramidase DUF2070 PF09843.9 EER28077.1 - 1.1 7.5 5.3 1.4 7.1 5.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Abhydrolase_6 PF12697.7 EER28078.1 - 5.8e-11 43.4 0.0 8.2e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER28078.1 - 9.4e-05 21.8 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EER28078.1 - 0.032 13.7 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.20 EER28078.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 EER28078.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold RTT107_BRCT_5 PF16770.5 EER28079.1 - 1.8e-35 120.8 1.8 2.3e-32 110.9 0.1 3.9 5 0 0 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 EER28079.1 - 4.9e-31 106.5 1.1 1.8e-20 72.7 0.2 4.9 4 1 0 4 4 4 2 twin BRCT domain BRCT_2 PF16589.5 EER28079.1 - 2.1e-29 101.7 0.0 2.6e-05 24.6 0.0 6.5 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EER28079.1 - 2e-27 95.4 0.0 2.8e-09 37.2 0.0 6.5 6 1 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EER28079.1 - 7.1e-06 26.2 0.0 0.094 13.0 0.0 4.0 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain ESCRT-II PF05871.12 EER28080.1 - 3.4e-53 179.7 0.0 4.6e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit DUF2156 PF09924.9 EER28080.1 - 0.07 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) DUF2786 PF10979.8 EER28081.1 - 3.5e-14 52.4 0.2 1.4e-13 50.5 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2786) NAD_binding_8 PF13450.6 EER28082.1 - 4.6e-09 36.4 0.5 1.1e-08 35.2 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EER28082.1 - 1.5e-07 31.1 0.1 2.6e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EER28082.1 - 4.7e-05 22.6 0.6 0.00018 20.7 1.0 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EER28082.1 - 0.00036 19.9 0.2 0.00078 18.8 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER28082.1 - 0.00046 19.0 0.5 0.00075 18.3 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EER28082.1 - 0.0077 15.8 0.6 0.032 13.8 0.5 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EER28082.1 - 0.013 16.1 0.1 0.057 14.0 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EER28082.1 - 0.043 13.1 0.1 0.06 12.6 0.1 1.5 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase GIDA PF01134.22 EER28082.1 - 0.096 11.7 0.9 0.17 10.9 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF4945 PF16303.5 EER28082.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4945) Pyr_redox_3 PF13738.6 EER28082.1 - 0.16 11.1 0.3 0.27 10.4 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EER28083.1 - 3.9e-17 62.5 0.5 2.3e-16 60.0 0.5 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EER28083.1 - 3.1e-05 24.0 0.0 0.00013 22.0 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EER28083.1 - 0.0012 19.0 0.4 0.003 17.8 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER28083.1 - 0.0013 18.4 5.8 0.0082 15.8 3.6 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER28083.1 - 0.0033 16.7 0.2 0.029 13.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EER28083.1 - 0.0068 15.3 1.2 1 8.1 1.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Trimer_CC PF08954.11 EER28083.1 - 0.037 13.6 0.3 0.072 12.7 0.3 1.4 1 0 0 1 1 1 0 Trimerisation motif Lycopene_cycl PF05834.12 EER28083.1 - 0.088 11.8 1.3 3 6.8 1.3 2.3 1 1 0 1 1 1 0 Lycopene cyclase protein SE PF08491.10 EER28083.1 - 0.17 10.9 0.0 0.87 8.6 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.24 EER28083.1 - 0.18 10.9 1.5 0.27 10.3 1.5 1.2 1 0 0 1 1 1 0 FAD binding domain ketoacyl-synt PF00109.26 EER28084.1 - 1.2e-70 238.0 0.4 3.7e-70 236.4 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 EER28084.1 - 2.5e-34 117.0 0.1 9.9e-34 115.1 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 EER28084.1 - 2e-28 98.8 0.0 4.3e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EER28084.1 - 1.5e-26 93.7 0.1 3.6e-24 85.8 0.1 2.3 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.12 EER28084.1 - 5.6e-26 91.3 0.0 9.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein SAT PF16073.5 EER28084.1 - 5e-15 55.9 4.3 7.8e-12 45.4 0.1 3.4 2 1 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis PP-binding PF00550.25 EER28084.1 - 8.9e-14 51.6 0.5 2.6e-13 50.1 0.5 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 EER28084.1 - 2e-13 50.9 0.0 6.3e-13 49.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER28084.1 - 3.7e-08 34.0 0.0 1.3e-07 32.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EER28084.1 - 9.9e-08 31.7 0.3 4.1e-06 26.3 0.1 2.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 EER28084.1 - 2.6e-07 31.2 0.0 9.3e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EER28084.1 - 8.7e-07 28.6 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 EER28084.1 - 1.2e-06 28.4 0.0 4.4e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER28084.1 - 2.2e-06 27.6 0.0 6.6e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EER28084.1 - 0.00091 19.7 0.0 0.0026 18.2 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension KR PF08659.10 EER28084.1 - 0.003 17.5 0.0 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EER28084.1 - 0.033 13.3 0.0 0.073 12.2 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ACP_syn_III PF08545.10 EER28084.1 - 0.068 13.0 0.3 0.21 11.4 0.3 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FSH1 PF03959.13 EER28085.1 - 1.1e-35 123.2 0.0 1.4e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 EER28085.1 - 0.11 12.3 0.0 2.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase MFS_1 PF07690.16 EER28086.1 - 8e-22 77.6 45.4 8e-22 77.6 45.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily YCII PF03795.14 EER28087.1 - 3.3e-10 40.2 0.0 3.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DIOX_N PF14226.6 EER28088.1 - 1.9e-33 115.7 0.0 3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EER28088.1 - 4.8e-20 71.9 0.0 1.1e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 EER28089.1 - 1.3e-18 67.1 4.1 2.1e-18 66.3 1.5 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28089.1 - 1.6e-09 37.7 9.0 2.9e-09 36.9 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 EER28090.1 - 2.4e-12 46.9 0.7 4e-12 46.2 0.7 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER28090.1 - 1.5e-08 34.5 0.0 8.4e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EER28090.1 - 0.0034 18.4 0.0 0.006 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YCII PF03795.14 EER28091.1 - 3e-09 37.2 0.0 3.8e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Methyltransf_4 PF02390.17 EER28092.1 - 1.4e-45 154.9 0.1 7.3e-44 149.3 0.1 2.8 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EER28092.1 - 0.00028 20.5 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_25 PF13649.6 EER28092.1 - 0.0037 17.9 0.0 0.035 14.8 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER28092.1 - 0.0083 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF913 PF06025.12 EER28092.1 - 0.014 14.4 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CCDC24 PF15669.5 EER28092.1 - 0.032 14.1 2.4 0.054 13.4 2.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family Methyltransf_12 PF08242.12 EER28092.1 - 0.092 13.5 0.0 0.25 12.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain LIM PF00412.22 EER28093.1 - 2.9e-26 91.5 24.7 1.5e-10 41.1 3.3 3.9 3 1 0 3 3 3 3 LIM domain DZR PF12773.7 EER28093.1 - 0.015 15.3 4.1 0.015 15.3 4.1 4.4 4 2 0 4 4 4 0 Double zinc ribbon Zn_ribbon_recom PF13408.6 EER28093.1 - 0.015 15.8 0.1 0.015 15.8 0.1 3.2 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain CG-1 PF03859.16 EER28093.1 - 0.068 13.0 0.1 0.19 11.5 0.1 1.7 2 0 0 2 2 2 0 CG-1 domain MFS_1 PF07690.16 EER28094.1 - 1.5e-22 80.0 42.9 1.5e-22 80.0 42.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EER28094.1 - 1.7e-07 30.2 23.8 6e-05 21.8 9.7 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EER28094.1 - 7.3e-06 25.1 16.0 0.0024 16.8 0.2 2.5 2 1 0 2 2 2 2 MFS_1 like family RNB PF00773.19 EER28095.1 - 3.7e-96 322.3 0.3 7.1e-96 321.4 0.1 1.6 2 0 0 2 2 2 1 RNB domain Rrp44_CSD1 PF17216.3 EER28095.1 - 4e-29 101.2 0.0 1.8e-28 99.1 0.0 2.2 1 1 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EER28095.1 - 4.8e-26 90.6 1.3 1.3e-25 89.2 1.3 1.7 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EER28095.1 - 3.3e-20 71.9 0.0 1.1e-19 70.2 0.0 2.0 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EER28095.1 - 8.6e-11 42.2 0.2 2.2e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EER28095.1 - 6.1e-09 35.9 0.0 2.6e-05 24.3 0.0 2.9 2 0 0 2 2 2 2 Cold shock domain CN_hydrolase PF00795.22 EER28096.1 - 2.2e-50 171.4 0.0 2.5e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ESSS PF10183.9 EER28097.1 - 2.8e-15 56.4 0.0 3.2e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ACOX PF01756.19 EER28098.1 - 3.9e-47 160.1 0.1 7.8e-47 159.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EER28098.1 - 5.3e-30 104.5 1.0 1.1e-29 103.6 1.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EER28098.1 - 1.5e-11 44.3 0.0 6.1e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EER28098.1 - 1.5e-06 28.5 0.1 0.0035 17.6 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain HTH_31 PF13560.6 EER28098.1 - 0.12 12.7 0.7 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Beta-lactamase PF00144.24 EER28100.1 - 7.8e-37 127.2 0.1 2.6e-36 125.5 0.0 1.7 1 1 1 2 2 2 1 Beta-lactamase AIP3 PF03915.13 EER28101.1 - 3.2e-158 527.1 9.3 5.2e-158 526.4 9.3 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 EER28101.1 - 0.00032 20.4 0.2 0.0014 18.3 0.2 2.2 1 1 0 1 1 1 1 Hepatic lectin, N-terminal domain MIP-T3_C PF17749.1 EER28101.1 - 0.0052 16.8 3.4 0.012 15.5 1.1 2.7 2 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region RasGAP_C PF03836.15 EER28101.1 - 0.033 14.3 3.5 0.13 12.4 0.4 3.4 4 1 0 4 4 4 0 RasGAP C-terminus DUF1664 PF07889.12 EER28101.1 - 0.81 9.7 6.3 4 7.5 1.0 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.15 EER28101.1 - 0.91 9.3 8.4 1.2 8.9 0.1 3.7 3 0 0 3 3 3 0 Septum formation initiator GNVR PF13807.6 EER28101.1 - 1.1 9.2 5.1 6.1 6.8 0.1 3.1 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase LsmAD PF06741.13 EER28102.1 - 7.9e-28 96.8 2.6 7.9e-28 96.8 2.6 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 EER28102.1 - 8.5e-23 80.3 0.0 1.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.25 EER28103.1 - 1.6e-10 40.8 0.0 3.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EER28103.1 - 9.2e-08 31.7 0.1 0.21 11.9 0.0 4.9 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EER28103.1 - 2.8e-07 30.7 0.1 1.2e-05 25.4 0.0 2.3 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase_Tyr PF07714.17 EER28103.1 - 1.8e-05 24.2 0.0 3.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EER28103.1 - 2.5e-05 24.6 2.9 0.0061 16.9 0.1 4.0 2 1 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.6 EER28103.1 - 0.00042 20.8 0.9 0.89 10.1 0.2 3.6 3 1 1 4 4 4 2 HEAT-like repeat Adaptin_N PF01602.20 EER28103.1 - 0.0027 16.3 0.0 0.092 11.3 0.0 2.1 1 1 0 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.8 EER28103.1 - 0.037 13.6 0.2 0.41 10.2 0.2 2.1 1 1 2 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 EER28103.1 - 0.066 13.8 0.1 11 6.7 0.0 2.9 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Kinase-like PF14531.6 EER28103.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like CoA_trans PF01144.23 EER28103.1 - 0.19 11.1 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase adh_short_C2 PF13561.6 EER28104.1 - 3.7e-30 105.2 0.0 1.6e-24 86.8 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER28104.1 - 1e-27 96.9 0.0 1.7e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER28104.1 - 8.6e-05 22.5 0.0 0.00019 21.4 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EER28104.1 - 0.00017 21.1 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Dabb PF07876.12 EER28105.1 - 4.7e-20 72.0 0.2 5.3e-20 71.9 0.2 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Macoilin PF09726.9 EER28106.1 - 0.0017 17.0 11.9 0.0017 17.0 11.9 2.0 2 0 0 2 2 2 1 Macoilin family Spc7 PF08317.11 EER28106.1 - 0.0019 17.2 9.0 0.0036 16.3 9.0 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein Golgin_A5 PF09787.9 EER28106.1 - 0.0061 16.1 11.8 0.015 14.8 11.8 1.6 1 0 0 1 1 1 1 Golgin subfamily A member 5 Tup_N PF08581.10 EER28106.1 - 0.016 15.5 10.4 0.42 11.0 2.2 2.9 3 0 0 3 3 3 0 Tup N-terminal DUF4407 PF14362.6 EER28106.1 - 0.27 10.6 13.2 0.19 11.1 10.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 EER28106.1 - 0.57 10.4 6.1 1.5 9.1 5.0 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain BicD PF09730.9 EER28106.1 - 0.59 8.5 11.4 1.1 7.6 10.9 1.5 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D CENP-Q PF13094.6 EER28106.1 - 1.7 8.8 16.3 12 6.0 0.0 2.9 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FUSC PF04632.12 EER28106.1 - 2 6.9 3.4 4.4 5.7 3.4 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 EER28106.1 - 2.2 6.8 5.1 4.4 5.8 5.1 1.5 1 0 0 1 1 1 0 Flagellar Assembly Protein A MADF_DNA_bdg PF10545.9 EER28106.1 - 6.3 7.2 8.4 12 6.3 4.8 2.9 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like YabA PF06156.13 EER28106.1 - 7 7.4 8.7 16 6.2 4.6 2.8 2 0 0 2 2 2 0 Initiation control protein YabA Acetyltransf_1 PF00583.25 EER28107.1 - 5.6e-11 42.7 0.0 9.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER28107.1 - 1e-07 31.9 0.2 1.5e-07 31.4 0.2 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER28107.1 - 2.3e-07 30.7 0.1 3.7e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EER28107.1 - 3e-05 24.4 0.0 5.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER28107.1 - 0.01 15.9 0.4 0.018 15.1 0.4 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1793 PF08760.11 EER28107.1 - 0.11 12.9 0.1 0.16 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1793) DJ-1_PfpI PF01965.24 EER28109.1 - 1.4e-14 54.3 0.0 1.7e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family SUR7 PF06687.12 EER28110.1 - 1.4e-41 142.5 5.3 1.4e-41 142.5 5.3 1.4 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EER28110.1 - 0.97 9.3 11.0 0.15 11.9 6.6 1.7 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Yuri_gagarin PF15934.5 EER28111.1 - 0.002 18.0 2.5 0.0035 17.2 2.5 1.2 1 0 0 1 1 1 1 Yuri gagarin CREPT PF16566.5 EER28111.1 - 0.014 15.5 1.5 0.032 14.4 1.5 1.5 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Syntaxin PF00804.25 EER28111.1 - 0.29 10.8 2.2 0.51 10.0 2.2 1.3 1 0 0 1 1 1 0 Syntaxin WD40 PF00400.32 EER28112.1 - 2e-38 129.7 18.5 1.3e-09 38.5 0.1 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER28112.1 - 2.2e-09 37.5 1.8 0.025 14.9 0.1 4.5 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER28112.1 - 3e-08 32.8 1.4 0.0087 14.8 0.0 4.5 3 1 1 4 4 4 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EER28112.1 - 5.1e-06 25.6 0.7 1.6e-05 24.0 0.1 2.1 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 EER28112.1 - 0.00018 20.6 0.1 0.87 8.5 0.0 3.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 EER28112.1 - 0.057 12.5 0.8 7.4 5.6 0.0 2.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.11 EER28112.1 - 0.11 11.3 0.0 1.3 7.7 0.0 2.5 2 1 0 2 2 2 0 Nup133 N terminal like Hira PF07569.11 EER28112.1 - 0.13 12.0 0.6 2.6 7.7 0.4 3.0 1 1 1 2 2 2 0 TUP1-like enhancer of split Tctex-1 PF03645.13 EER28113.1 - 6.5e-35 119.5 0.0 7.8e-35 119.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF1031 PF06275.11 EER28113.1 - 0.04 14.2 0.0 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) Pkinase PF00069.25 EER28114.1 - 2.8e-11 43.3 0.0 3.5e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF202 PF02656.15 EER28115.1 - 5.7e-14 52.3 5.0 5.7e-14 52.3 5.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 EER28115.1 - 3 7.7 8.9 0.6 10.0 5.0 2.0 2 1 0 2 2 2 0 Family of unknown function (DUF5337) Metallophos_2 PF12850.7 EER28117.1 - 7.1e-13 49.1 0.0 8.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 EER28118.1 - 2.7e-15 55.9 0.0 4.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spectrin PF00435.21 EER28118.1 - 0.035 14.6 2.3 0.19 12.2 2.7 1.8 1 1 1 2 2 2 0 Spectrin repeat Nup35_RRM_2 PF14605.6 EER28118.1 - 0.063 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Spc7 PF08317.11 EER28118.1 - 0.07 12.0 2.4 0.092 11.6 2.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF724 PF05266.14 EER28118.1 - 0.072 12.9 1.0 0.097 12.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.8 EER28118.1 - 0.082 12.2 1.8 0.11 11.8 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) EMP24_GP25L PF01105.24 EER28118.1 - 0.18 11.7 0.5 0.25 11.2 0.5 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD bZIP_1 PF00170.21 EER28118.1 - 0.25 11.4 5.6 0.37 10.9 5.6 1.2 1 0 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 EER28118.1 - 0.4 10.5 5.5 0.61 9.9 5.5 1.2 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 EER28118.1 - 0.42 11.1 5.1 0.71 10.4 5.1 1.2 1 0 0 1 1 1 0 Cell division protein ZapB APG6_N PF17675.1 EER28118.1 - 1.2 9.6 6.9 1.7 9.2 6.9 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region GRP PF07172.11 EER28118.1 - 1.5 9.5 21.7 0.46 11.2 18.8 1.7 2 0 0 2 2 2 0 Glycine rich protein family HECT PF00632.25 EER28119.1 - 2.4e-98 329.4 0.0 3.3e-98 329.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EER28119.1 - 3e-31 107.2 27.5 1.7e-12 47.2 3.3 4.7 5 0 0 5 5 5 3 WW domain C2 PF00168.30 EER28119.1 - 7.3e-20 71.2 0.0 1.8e-19 69.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain HHH PF00633.23 EER28120.1 - 0.019 14.8 0.4 0.073 13.0 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif ComFB PF10719.9 EER28120.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Late competence development protein ComFB Aminotran_5 PF00266.19 EER28121.1 - 3.8e-32 111.6 0.0 4.7e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 EER28121.1 - 0.055 13.5 0.1 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 B12 binding domain OspD PF03207.13 EER28121.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) NIF PF03031.18 EER28122.1 - 1.3e-56 190.7 0.0 1.8e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Importin_rep_3 PF18806.1 EER28122.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Importin 13 repeat IF-2B PF01008.17 EER28123.1 - 5e-58 196.6 0.0 1e-38 133.2 0.1 2.3 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.25 EER28124.1 - 1e-50 170.1 0.7 1.2e-50 169.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 EER28125.1 - 1.5e-21 76.0 4.7 3.3e-21 74.9 4.7 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) Ribosomal_L17 PF01196.19 EER28126.1 - 1.7e-33 115.4 0.0 2.9e-33 114.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Mrpl_C PF18502.1 EER28126.1 - 0.032 14.5 0.1 0.16 12.3 0.0 1.9 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Molybdopterin_N PF18364.1 EER28126.1 - 0.17 11.9 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain SUZ PF12752.7 EER28127.1 - 5.5e-15 55.9 10.6 5.5e-15 55.9 10.6 4.4 4 1 0 4 4 4 1 SUZ domain R3H PF01424.22 EER28127.1 - 6.8e-08 32.4 0.0 1.6e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain GREB1 PF15782.5 EER28128.1 - 4.4 4.3 7.8 4.9 4.1 7.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer cwf18 PF08315.12 EER28129.1 - 8.2e-45 152.8 7.0 8.2e-45 152.8 7.0 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.6 EER28130.1 - 2.4e-09 37.2 1.3 4.5e-06 26.7 0.0 4.1 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.20 EER28130.1 - 1.2e-06 28.4 0.4 0.097 13.0 0.0 4.4 5 0 0 5 5 5 2 PPR repeat DUF1242 PF06842.12 EER28131.1 - 3.8e-18 65.0 0.2 5.7e-18 64.4 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 EER28132.1 - 3.4e-23 81.5 0.0 5.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 EER28132.1 - 2.3e-05 24.7 0.1 5.5e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EER28132.1 - 0.0011 19.1 0.1 0.0025 17.9 0.1 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EER28132.1 - 0.12 12.7 0.1 0.27 11.6 0.1 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EER28132.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated JAB PF01398.21 EER28133.1 - 7e-20 71.2 0.0 1.3e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EER28133.1 - 1.4e-10 41.6 0.1 2.7e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 EER28133.1 - 0.00012 22.2 0.0 0.0002 21.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) UTP25 PF06862.12 EER28134.1 - 1e-197 657.6 0.0 1.2e-197 657.4 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EER28134.1 - 0.00025 20.9 0.0 0.0099 15.7 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase EamA PF00892.20 EER28135.1 - 1e-18 67.8 20.2 8e-14 52.0 4.0 3.1 3 0 0 3 3 3 3 EamA-like transporter family IMUP PF15761.5 EER28135.1 - 0.96 10.2 4.1 2.5 8.8 4.1 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein CTP_transf_like PF01467.26 EER28136.1 - 2.5e-31 108.8 0.0 4.6e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like HIGH_NTase1 PF05636.11 EER28136.1 - 0.14 11.3 0.1 0.24 10.6 0.1 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Dscam_C PF12355.8 EER28136.1 - 4.1 8.4 11.2 1.6 9.7 7.3 2.3 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal PP2C PF00481.21 EER28137.1 - 1.3e-80 270.8 0.0 1.8e-80 270.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Acetyltransf_1 PF00583.25 EER28138.1 - 1.7e-16 60.5 0.0 2e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER28138.1 - 1.2e-12 47.9 0.1 1.5e-12 47.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER28138.1 - 1.9e-12 47.4 0.0 2.6e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER28138.1 - 5.9e-09 35.8 0.1 9.7e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EER28138.1 - 0.00029 21.0 0.0 0.00041 20.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER28138.1 - 0.00038 20.5 0.1 0.00076 19.6 0.1 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 EER28138.1 - 0.00098 18.8 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER28138.1 - 0.0011 19.0 0.0 0.0014 18.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EER28138.1 - 0.016 15.0 0.2 0.026 14.3 0.2 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ DpnI_C PF17726.1 EER28138.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Dam-replacing HTH domain Acetyltransf_3 PF13302.7 EER28138.1 - 0.042 14.5 0.0 0.053 14.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EER28138.1 - 0.048 13.8 0.1 0.097 12.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.8 EER28139.1 - 3.8e-26 90.6 1.4 4.4e-26 90.4 1.4 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated WXG100 PF06013.12 EER28139.1 - 0.01 16.1 0.0 1.8 8.9 0.0 2.0 2 0 0 2 2 2 0 Proteins of 100 residues with WXG CUE PF02845.16 EER28140.1 - 1.4e-10 40.7 0.0 2.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain TBCA PF02970.16 EER28140.1 - 0.86 10.0 5.4 1.7 9.0 0.1 2.9 3 0 0 3 3 3 0 Tubulin binding cofactor A HA2 PF04408.23 EER28141.1 - 1.7e-17 63.6 0.0 4e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EER28141.1 - 7.1e-14 51.9 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EER28141.1 - 1.6e-11 44.6 0.0 4.3e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EER28141.1 - 1.7e-05 24.7 0.1 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 EER28141.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EER28141.1 - 0.00013 22.2 0.1 0.00038 20.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EER28141.1 - 0.00034 21.0 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EER28141.1 - 0.0018 17.9 0.1 0.031 13.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EER28141.1 - 0.025 14.6 0.6 3 7.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 EER28141.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EER28141.1 - 0.12 12.9 2.1 0.19 12.2 0.1 2.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EER28141.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 EER28141.1 - 0.15 11.3 0.3 0.44 9.8 0.1 1.8 1 1 1 2 2 2 0 Zeta toxin PITH PF06201.13 EER28142.1 - 2.1e-43 148.2 0.0 2.5e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.21 EER28143.1 - 1.7e-34 118.9 5.4 2.2e-34 118.5 5.4 1.1 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.16 EER28143.1 - 0.042 14.1 0.2 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain GCIP PF13324.6 EER28143.1 - 0.88 9.1 6.4 1.9 8.0 0.9 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting AAA PF00004.29 EER28144.1 - 1.2e-89 297.5 0.0 6.8e-44 149.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER28144.1 - 1.4e-19 69.6 0.1 5.3e-09 35.7 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EER28144.1 - 4.2e-14 53.3 0.7 5.7e-05 23.6 0.1 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EER28144.1 - 9.7e-14 51.8 0.3 0.024 14.9 0.0 5.4 2 2 2 5 5 5 2 AAA domain RuvB_N PF05496.12 EER28144.1 - 1.7e-13 50.6 0.0 4.4e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EER28144.1 - 6e-11 42.8 0.0 6.7e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EER28144.1 - 6.9e-11 42.3 0.1 0.0011 19.0 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EER28144.1 - 5.1e-10 39.7 0.0 0.00026 21.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EER28144.1 - 1.4e-08 34.4 0.0 0.00022 20.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EER28144.1 - 5e-08 33.3 0.0 0.0031 17.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EER28144.1 - 2.9e-07 30.6 0.0 0.0099 15.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EER28144.1 - 7.1e-07 29.1 0.1 0.031 14.0 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EER28144.1 - 7.7e-07 29.5 0.0 0.014 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EER28144.1 - 1.5e-06 27.7 0.2 0.04 13.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EER28144.1 - 1.6e-06 28.7 0.0 0.035 14.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 EER28144.1 - 3.3e-06 26.5 0.0 0.052 12.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 EER28144.1 - 6.1e-06 26.2 0.0 0.1 12.6 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EER28144.1 - 6.7e-06 26.0 0.0 0.023 14.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EER28144.1 - 2.3e-05 23.9 0.1 0.21 10.9 0.0 3.1 2 1 0 2 2 2 2 KaiC Cytidylate_kin2 PF13189.6 EER28144.1 - 2.8e-05 24.3 0.0 0.006 16.7 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_25 PF13481.6 EER28144.1 - 2.8e-05 23.8 1.6 2.4 7.7 0.0 4.1 3 1 0 4 4 4 1 AAA domain Rad17 PF03215.15 EER28144.1 - 3.2e-05 23.9 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 EER28144.1 - 4.8e-05 23.0 0.0 0.22 11.0 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 EER28144.1 - 7.3e-05 22.5 0.0 0.27 10.9 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EER28144.1 - 7.5e-05 23.3 0.0 0.3 11.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter NACHT PF05729.12 EER28144.1 - 7.6e-05 22.7 0.1 1.1 9.2 0.0 3.4 4 0 0 4 4 3 2 NACHT domain AAA_17 PF13207.6 EER28144.1 - 0.00024 21.5 0.0 0.45 10.9 0.0 3.0 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EER28144.1 - 0.00044 19.8 0.0 0.59 9.6 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.6 EER28144.1 - 0.00082 19.2 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EER28144.1 - 0.00086 18.6 0.0 1 8.5 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Sigma54_activ_2 PF14532.6 EER28144.1 - 0.0011 19.0 0.0 2.3 8.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.22 EER28144.1 - 0.0014 18.8 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA_24 PF13479.6 EER28144.1 - 0.0018 18.0 0.0 0.96 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 EER28144.1 - 0.0022 17.1 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 TniB PF05621.11 EER28144.1 - 0.0026 17.2 0.0 0.91 8.9 0.0 3.1 3 0 0 3 3 3 1 Bacterial TniB protein AFG1_ATPase PF03969.16 EER28144.1 - 0.0027 16.7 0.0 0.45 9.3 0.0 2.5 2 0 0 2 2 2 1 AFG1-like ATPase Viral_helicase1 PF01443.18 EER28144.1 - 0.003 17.4 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EER28144.1 - 0.0034 17.3 0.0 2 8.3 0.0 3.3 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EER28144.1 - 0.0051 16.0 0.0 0.081 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EER28144.1 - 0.015 15.6 1.3 5.2 7.4 0.2 3.0 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EER28144.1 - 0.016 14.4 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CPT PF07931.12 EER28144.1 - 0.028 14.3 0.0 0.77 9.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 EER28144.1 - 0.057 13.4 0.0 18 5.3 0.0 2.7 2 1 1 3 3 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EER28144.1 - 0.092 12.6 0.0 7.1 6.5 0.0 2.7 2 1 1 3 3 2 0 NTPase SRPRB PF09439.10 EER28144.1 - 0.16 11.4 0.0 21 4.5 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_30 PF13604.6 EER28144.1 - 0.18 11.5 0.1 29 4.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 EER28144.1 - 0.23 10.8 0.1 19 4.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase BOP1NT PF08145.12 EER28145.1 - 7.8e-105 350.5 9.6 1.2e-104 349.8 9.6 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EER28145.1 - 4e-22 78.1 6.8 2.7e-09 37.5 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER28145.1 - 2.2e-07 31.0 0.0 0.0035 17.6 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3947 PF13135.6 EER28145.1 - 0.24 11.6 0.2 0.57 10.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Zn_clus PF00172.18 EER28146.1 - 9.3e-09 35.3 7.1 2e-08 34.2 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UBM PF14377.6 EER28146.1 - 0.15 11.6 0.1 0.3 10.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Leo1 PF04004.13 EER28147.1 - 1e-29 103.5 0.2 4.8e-29 101.3 0.2 2.0 1 1 0 1 1 1 1 Leo1-like protein Mob1_phocein PF03637.17 EER28148.1 - 1.1e-51 175.2 0.1 1.6e-50 171.4 0.1 2.1 1 1 0 1 1 1 1 Mob1/phocein family ZapB PF06005.12 EER28149.1 - 0.57 10.7 3.3 6.2 7.3 0.4 2.4 1 1 1 2 2 2 0 Cell division protein ZapB Rhomboid PF01694.22 EER28150.1 - 2.6e-18 66.4 3.8 5e-18 65.5 3.8 1.4 1 0 0 1 1 1 1 Rhomboid family Trypan_PARP PF05887.11 EER28151.1 - 0.2 11.6 7.6 0.34 10.9 7.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 EER28151.1 - 1.5 8.8 14.3 1.6 8.6 14.3 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EER28151.1 - 2.6 8.7 13.3 3.2 8.4 13.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PhoD PF09423.10 EER28152.1 - 1.9e-07 30.4 0.1 0.00027 20.1 0.1 3.0 3 0 0 3 3 3 2 PhoD-like phosphatase Pkinase_fungal PF17667.1 EER28153.1 - 7.8e-114 380.6 0.0 9e-114 380.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EER28153.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EER28153.1 - 0.0051 16.4 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EER28153.1 - 0.0078 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EER28154.1 - 6.4e-26 91.3 0.0 2.6e-25 89.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER28154.1 - 6.7e-06 25.6 0.0 1.9e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EER28154.1 - 0.0068 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Gryzun PF07919.12 EER28158.1 - 2.1e-237 789.6 0.0 2.6e-237 789.4 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EER28158.1 - 3.7e-100 334.8 1.1 4.5e-90 301.7 3.1 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 TRAPPC9-Trs120 PF08626.11 EER28158.1 - 0.0053 14.2 0.0 0.0074 13.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Gryzun-like PF12742.7 EER28158.1 - 0.011 15.8 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking TMEM131_like PF12371.8 EER28158.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Transmembrane protein 131-like Abhydrolase_1 PF00561.20 EER28159.1 - 3.4e-09 36.7 0.0 9.8e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER28159.1 - 3.5e-09 37.6 3.4 1e-07 32.8 3.4 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER28159.1 - 1.7e-06 27.5 0.0 4.9e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Glutaredoxin PF00462.24 EER28160.1 - 8.2e-14 51.6 0.0 1.9e-13 50.4 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.6 EER28160.1 - 0.0075 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L6 PF00347.23 EER28161.1 - 8.7e-25 87.2 6.9 1.6e-12 47.9 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DUF3336 PF11815.8 EER28162.1 - 3.4e-31 107.8 0.0 6.5e-31 106.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EER28162.1 - 9.1e-13 48.8 0.0 2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase RXT2_N PF08595.11 EER28163.1 - 1.3e-37 129.2 0.1 1.3e-37 129.2 0.1 2.5 2 1 0 2 2 2 1 RXT2-like, N-terminal PEMT PF04191.13 EER28164.1 - 5.9e-33 113.4 5.7 1.5e-32 112.1 3.4 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase PXA PF02194.15 EER28165.1 - 1.2e-49 168.7 0.5 4.8e-49 166.8 0.5 2.1 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EER28165.1 - 6e-27 94.4 0.0 2.7e-26 92.3 0.1 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EER28165.1 - 3.7e-21 75.2 0.2 8.9e-21 74.0 0.2 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EER28165.1 - 2.5e-10 40.7 0.0 6.6e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Aldo_ket_red PF00248.21 EER28167.1 - 1.2e-61 208.5 0.3 1.7e-61 208.0 0.3 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NT5C PF06941.12 EER28167.1 - 0.051 13.4 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 7TM_GPCR_Srd PF10317.9 EER28167.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd WD40 PF00400.32 EER28168.1 - 1.7e-16 60.3 11.0 0.0011 19.7 0.1 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER28168.1 - 9.1e-06 25.9 0.0 0.07 13.4 0.0 4.6 2 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EER28168.1 - 0.01 14.8 0.1 0.16 10.9 0.0 2.5 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EER28168.1 - 0.01 14.5 0.9 0.091 11.4 0.3 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EER28168.1 - 0.033 13.5 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain PilX PF13681.6 EER28168.1 - 0.07 13.5 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Type IV pilus assembly protein PilX C-term FliO PF04347.13 EER28168.1 - 0.14 12.4 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO tRNA-synt_1g PF09334.11 EER28169.1 - 2.6e-150 500.6 0.0 3.2e-150 500.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EER28169.1 - 2.3e-08 32.8 0.1 3.3e-05 22.4 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) RNA_polI_A34 PF08208.11 EER28169.1 - 0.0013 18.8 8.1 0.002 18.3 8.1 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 PepSY PF03413.19 EER28169.1 - 0.41 11.2 3.5 1 10.0 0.0 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Elongin_A PF06881.11 EER28169.1 - 3.9 8.1 6.3 2.2 8.8 3.4 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A BRF1 PF07741.13 EER28169.1 - 4.1 7.8 10.3 12 6.3 10.3 1.7 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Yae1_N PF09811.9 EER28170.1 - 8.9e-06 25.3 4.7 8.9e-06 25.3 4.7 1.9 2 0 0 2 2 2 1 Essential protein Yae1, N terminal UPF0160 PF03690.13 EER28171.1 - 1.5e-120 402.6 0.0 1.7e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 EER28172.1 - 1.3e-157 525.1 12.6 1.5e-157 524.9 12.6 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.17 EER28173.1 - 2e-28 98.4 0.1 3.6e-28 97.5 0.1 1.5 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 EER28174.1 - 3.6e-73 245.4 0.0 4.1e-73 245.2 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 EER28175.1 - 4.1e-118 395.4 0.0 5.4e-118 395.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase WD40 PF00400.32 EER28176.1 - 3.1e-28 97.4 19.8 8.8e-06 26.4 1.3 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER28176.1 - 2.3e-09 37.4 5.9 0.09 13.1 0.4 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EER28176.1 - 0.12 11.4 0.2 0.2 10.6 0.2 1.3 1 0 0 1 1 1 0 Coatomer WD associated region MHYT PF03707.16 EER28177.1 - 1.6e-18 66.6 20.4 2e-09 37.5 1.8 4.5 4 0 0 4 4 4 4 Bacterial signalling protein N terminal repeat DUF4271 PF14093.6 EER28177.1 - 0.069 13.1 10.5 0.17 11.8 5.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) Tcp11 PF05794.13 EER28178.1 - 1.3e-110 370.6 5.4 4.1e-110 368.9 0.0 2.3 2 0 0 2 2 2 1 T-complex protein 11 IQ PF00612.27 EER28178.1 - 0.0083 15.8 0.9 0.028 14.2 0.9 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Linker_histone PF00538.19 EER28178.1 - 0.41 11.0 0.0 0.41 11.0 0.0 2.7 3 0 0 3 3 3 0 linker histone H1 and H5 family DUF1204 PF06721.11 EER28178.1 - 0.55 9.6 13.4 1.4 8.3 13.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) UPF0242 PF06785.11 EER28178.1 - 1.1 9.3 5.0 3 7.9 5.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AtuA PF07287.11 EER28179.1 - 2.6e-114 381.6 0.0 3.1e-114 381.4 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA HMA PF00403.26 EER28180.1 - 2e-16 60.2 0.5 2.4e-16 59.9 0.5 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 EER28180.1 - 0.069 13.5 0.1 0.15 12.5 0.1 1.6 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain DUF2293 PF10056.9 EER28181.1 - 1.8e-31 108.2 0.1 4.1e-31 107.1 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Complex1_LYR PF05347.15 EER28182.1 - 0.00098 19.1 0.9 0.0021 18.1 0.9 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) zinc_ribbon_6 PF14599.6 EER28183.1 - 8.5e-26 89.7 1.4 8.5e-26 89.7 1.4 3.7 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 EER28183.1 - 2.6e-19 69.5 23.5 2.6e-19 69.5 23.5 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EER28183.1 - 1.6e-09 37.9 7.4 1.6e-09 37.9 7.4 5.0 2 1 4 6 6 6 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER28183.1 - 4.2e-06 26.5 7.4 4.2e-06 26.5 7.4 4.7 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER28183.1 - 5.9e-06 26.2 6.0 5.9e-06 26.2 6.0 2.7 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EER28183.1 - 0.00082 19.2 7.1 0.00082 19.2 7.1 5.2 4 2 1 5 5 5 2 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EER28183.1 - 0.0012 18.7 3.4 0.0012 18.7 3.4 5.7 3 2 1 5 5 5 1 Prokaryotic RING finger family 1 TFIIA PF03153.13 EER28183.1 - 2.3 8.1 13.2 0.019 15.0 4.1 2.0 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_11 PF17123.5 EER28183.1 - 3.3 7.6 19.6 0.042 13.6 3.8 4.7 5 0 0 5 5 5 0 RING-like zinc finger Rrn6 PF10214.9 EER28184.1 - 2.2e-207 691.5 3.6 4.2e-207 690.6 3.6 1.4 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 EER28185.1 - 2.5e-24 85.2 0.1 1.5e-23 82.8 0.1 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Peptidase_S46 PF10459.9 EER28185.1 - 0.15 10.6 7.6 0.17 10.5 7.6 1.0 1 0 0 1 1 1 0 Peptidase S46 Filament PF00038.21 EER28185.1 - 2.1 7.9 21.6 0.98 8.9 15.3 2.0 1 1 1 2 2 2 0 Intermediate filament protein Atg14 PF10186.9 EER28185.1 - 2.4 7.2 9.0 3.5 6.6 9.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LMBR1 PF04791.16 EER28185.1 - 4.7 6.0 4.1 5.3 5.8 4.1 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FUSC PF04632.12 EER28185.1 - 7.5 5.0 9.2 8.8 4.7 9.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.32 EER28186.1 - 2.9e-22 78.5 17.6 1.4e-07 32.1 0.7 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER28186.1 - 4.2e-15 55.8 0.6 0.00033 20.9 0.6 4.5 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L32p PF01783.23 EER28186.1 - 1e-11 44.9 7.9 1.9e-11 44.1 7.9 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Cytochrom_D1 PF02239.16 EER28186.1 - 0.00055 18.6 0.0 0.074 11.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EER28186.1 - 0.0034 17.3 0.0 0.23 11.3 0.0 2.6 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 EER28186.1 - 0.005 16.6 0.1 0.16 11.7 0.0 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split Nup160 PF11715.8 EER28186.1 - 0.0079 14.9 0.0 0.26 9.9 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EER28186.1 - 0.019 13.9 0.4 1.8 7.4 0.0 2.9 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Stc1 PF12898.7 EER28186.1 - 0.036 14.6 0.4 0.036 14.6 0.4 1.7 2 0 0 2 2 2 0 Stc1 domain Septin PF00735.18 EER28187.1 - 9.1e-113 376.2 0.5 1.1e-112 375.9 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EER28187.1 - 5.9e-08 32.8 0.0 1e-07 32.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EER28187.1 - 1.1e-05 24.9 0.0 1.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 EER28187.1 - 4.5e-05 23.4 0.3 0.00025 21.0 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EER28187.1 - 0.0002 21.5 0.3 0.87 9.6 0.2 2.6 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 EER28187.1 - 0.00021 20.9 0.5 0.017 14.7 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EER28187.1 - 0.0032 17.0 0.1 0.009 15.5 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EER28187.1 - 0.0042 17.5 0.1 0.011 16.1 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EER28187.1 - 0.0055 15.9 0.1 0.0096 15.1 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 EER28187.1 - 0.0091 16.5 0.3 0.022 15.3 0.2 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EER28187.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EER28187.1 - 0.027 13.6 0.4 0.32 10.1 0.1 1.9 1 1 1 2 2 2 0 G-protein alpha subunit Gtr1_RagA PF04670.12 EER28187.1 - 0.04 13.3 0.1 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Roc PF08477.13 EER28187.1 - 0.041 14.1 0.0 0.085 13.1 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EER28187.1 - 0.059 12.7 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EER28187.1 - 0.08 13.4 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EER28187.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.21 EER28188.1 - 4.5e-64 215.5 0.0 5.1e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase MMR_HSR1 PF01926.23 EER28188.1 - 7.5e-06 26.0 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EER28188.1 - 1.2e-05 25.8 0.2 4.4e-05 23.9 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EER28188.1 - 9.8e-05 22.9 0.3 0.00057 20.4 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EER28188.1 - 0.00022 21.0 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EER28188.1 - 0.00023 21.4 0.1 0.002 18.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EER28188.1 - 0.0006 20.1 0.0 0.0013 19.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EER28188.1 - 0.00078 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 EER28188.1 - 0.0019 18.8 0.0 0.0044 17.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 EER28188.1 - 0.0036 17.5 0.1 0.0093 16.2 0.0 1.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EER28188.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase RsgA_GTPase PF03193.16 EER28188.1 - 0.0058 16.6 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 EER28188.1 - 0.0077 16.2 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EER28188.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 EER28188.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EER28188.1 - 0.014 15.9 0.1 0.029 14.8 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EER28188.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EER28188.1 - 0.017 14.2 0.0 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EER28188.1 - 0.02 14.6 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EER28188.1 - 0.022 14.7 0.1 0.038 13.9 0.0 1.4 1 1 0 1 1 1 0 NTPase AAA_5 PF07728.14 EER28188.1 - 0.025 14.6 0.0 0.093 12.7 0.0 2.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EER28188.1 - 0.027 13.7 0.0 0.069 12.4 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EER28188.1 - 0.056 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Gtr1_RagA PF04670.12 EER28188.1 - 0.063 12.6 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ras PF00071.22 EER28188.1 - 0.067 12.8 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Ras family Pox_A32 PF04665.12 EER28188.1 - 0.09 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Cytidylate_kin PF02224.18 EER28188.1 - 0.11 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_19 PF13245.6 EER28188.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EER28188.1 - 0.15 12.6 2.7 0.29 11.6 2.7 1.7 1 1 0 1 1 1 0 AAA domain GRAB PF10375.9 EER28189.1 - 8.9e-08 31.7 0.3 1.9e-07 30.7 0.3 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain SIKE PF05769.11 EER28189.1 - 0.0076 16.2 16.2 0.0076 16.2 16.2 2.9 1 1 2 3 3 3 1 SIKE family Fib_alpha PF08702.10 EER28189.1 - 0.017 15.3 29.6 0.097 12.9 13.8 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family COG5 PF10392.9 EER28189.1 - 0.056 13.6 18.5 0.1 12.8 8.4 3.2 2 2 0 2 2 2 0 Golgi transport complex subunit 5 FAM184 PF15665.5 EER28189.1 - 0.18 11.6 58.1 0.071 12.9 15.3 3.7 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B FliJ PF02050.16 EER28189.1 - 1.1 9.5 46.5 5.5 7.2 11.0 3.8 2 1 1 3 3 3 0 Flagellar FliJ protein Spc7 PF08317.11 EER28189.1 - 1.2 8.0 57.1 0.17 10.7 29.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.12 EER28189.1 - 6.4 6.8 19.7 1.1 9.3 2.4 3.4 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus NFACT-R_1 PF05670.13 EER28190.1 - 3.2e-32 111.4 0.0 4.7e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 EER28190.1 - 0.023 14.9 0.2 0.054 13.7 0.0 1.7 2 0 0 2 2 2 0 NFACT protein RNA binding domain Pkinase PF00069.25 EER28192.1 - 4.9e-11 42.5 0.0 6.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DAO PF01266.24 EER28193.1 - 4.4e-51 174.5 0.1 7.1e-51 173.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EER28193.1 - 6.8e-44 148.8 0.0 1.1e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EER28193.1 - 1.2e-11 44.4 0.1 2.3e-11 43.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EER28193.1 - 7.3e-05 22.3 0.3 0.0027 17.1 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER28193.1 - 0.0011 18.3 0.1 0.0023 17.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EER28193.1 - 0.0026 17.6 0.3 0.0051 16.7 0.3 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EER28193.1 - 0.003 17.8 0.5 0.014 15.6 0.2 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EER28193.1 - 0.021 15.4 0.1 0.24 12.0 0.1 2.5 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER28193.1 - 0.026 13.8 0.0 0.094 11.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER28193.1 - 0.032 12.9 0.6 0.053 12.2 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 EER28193.1 - 0.056 12.5 0.5 0.33 10.0 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EER28193.1 - 0.084 12.1 0.2 0.77 8.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain p450 PF00067.22 EER28194.1 - 5.3e-66 223.3 0.0 6.1e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DASH_Dad2 PF08654.10 EER28196.1 - 1.5e-31 108.7 0.3 1.9e-31 108.4 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Shugoshin_N PF07558.11 EER28197.1 - 7.2e-19 67.4 4.2 2.1e-18 65.9 4.2 1.9 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EER28197.1 - 2.5e-10 39.9 5.0 1.2e-09 37.8 5.0 2.3 1 0 0 1 1 1 1 Shugoshin C terminus Mod_r PF07200.13 EER28197.1 - 0.0053 16.9 1.0 0.011 15.8 1.0 1.5 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein bZIP_1 PF00170.21 EER28197.1 - 0.017 15.2 1.8 0.017 15.2 1.8 2.6 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 EER28197.1 - 0.12 12.5 1.9 0.48 10.5 1.9 2.2 1 1 0 1 1 1 0 Basic region leucine zipper GIT_CC PF16559.5 EER28197.1 - 0.15 12.0 0.9 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ZapB PF06005.12 EER28197.1 - 0.26 11.8 1.2 0.59 10.6 1.2 1.6 1 0 0 1 1 1 0 Cell division protein ZapB PPI_Ypi1 PF07491.11 EER28198.1 - 1e-24 86.1 8.2 1e-24 86.1 8.2 2.2 2 1 0 2 2 2 1 Protein phosphatase inhibitor AF-4 PF05110.13 EER28198.1 - 0.0004 18.7 6.3 0.0004 18.7 6.3 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein TFIIF_alpha PF05793.12 EER28198.1 - 0.051 12.2 8.7 0.06 11.9 8.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EER28198.1 - 0.29 9.4 5.6 0.33 9.2 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 EER28198.1 - 2.7 6.4 6.7 2.8 6.4 6.7 1.0 1 0 0 1 1 1 0 Macoilin family CCDC106 PF15794.5 EER28198.1 - 4 7.1 6.8 5.2 6.7 6.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 PNISR PF15996.5 EER28198.1 - 6.9 6.9 8.8 9.1 6.5 8.8 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CRM1_C PF08767.11 EER28200.1 - 6.8e-136 452.6 9.9 6.8e-136 452.6 9.9 3.1 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EER28200.1 - 2.1e-41 141.5 10.2 7.8e-41 139.6 6.9 3.2 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EER28200.1 - 3.4e-34 116.3 3.2 1.8e-33 114.0 3.1 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EER28200.1 - 2.9e-29 100.9 0.7 2.9e-29 100.9 0.7 3.0 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EER28200.1 - 6.8e-20 70.3 0.8 1.5e-19 69.2 0.8 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EER28200.1 - 7.3e-13 48.2 0.3 2.8e-12 46.4 0.3 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EER28200.1 - 0.011 15.6 0.7 0.3 11.0 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) HD_assoc PF13286.6 EER28200.1 - 0.018 15.6 2.1 9.5 6.8 0.0 3.9 4 0 0 4 4 4 0 Phosphohydrolase-associated domain Pre-PUA PF17832.1 EER28200.1 - 0.019 15.7 0.3 0.29 11.8 0.0 3.1 4 0 0 4 4 4 0 Pre-PUA-like domain Hemocyanin_M PF00372.19 EER28200.1 - 0.049 12.8 0.1 0.11 11.6 0.1 1.6 1 0 0 1 1 1 0 Hemocyanin, copper containing domain FAD_binding_3 PF01494.19 EER28201.1 - 6.3e-19 68.4 0.0 6.7e-18 65.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EER28201.1 - 7.9e-09 35.1 0.1 1.9e-08 33.9 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EER28201.1 - 4.4e-08 32.9 0.0 6.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EER28201.1 - 2.5e-07 30.6 6.5 0.0048 16.5 5.6 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER28201.1 - 4.6e-07 30.0 1.7 1.1e-06 28.8 1.7 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EER28201.1 - 5.1e-06 25.8 6.3 5.7e-06 25.7 5.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EER28201.1 - 9.9e-06 24.5 0.7 0.00094 18.0 2.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EER28201.1 - 1.4e-05 24.3 0.5 0.044 12.8 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.27 EER28201.1 - 6.1e-05 23.5 3.1 0.0022 18.5 1.6 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EER28201.1 - 7.8e-05 21.9 1.7 0.00012 21.3 1.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EER28201.1 - 0.0003 19.8 2.7 0.092 11.6 1.7 2.1 1 1 1 2 2 2 2 Tryptophan halogenase SE PF08491.10 EER28201.1 - 0.0052 15.9 0.0 0.0086 15.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 EER28201.1 - 0.0064 15.8 0.3 0.011 15.0 0.3 1.3 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EER28201.1 - 0.019 14.3 2.2 0.42 9.8 0.8 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DUF3629 PF12302.8 EER28201.1 - 0.02 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) 3HCDH_N PF02737.18 EER28201.1 - 0.046 13.6 1.8 0.085 12.7 1.8 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.9 EER28201.1 - 0.1 12.5 0.2 0.28 11.1 0.2 1.8 1 0 0 1 1 1 0 Rossmann-like domain Pyr_redox_3 PF13738.6 EER28201.1 - 0.15 11.3 1.2 0.45 9.7 1.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EER28201.1 - 0.18 11.1 0.7 0.37 10.1 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Mac_assoc PF16628.5 EER28202.1 - 1.6e-73 246.9 7.8 1.6e-73 246.9 7.8 2.6 2 1 0 2 2 2 1 Unstructured region on maltose acetyltransferase Hexapep PF00132.24 EER28202.1 - 8.4e-12 44.3 5.9 1e-07 31.4 0.3 3.6 2 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.18 EER28202.1 - 1.2e-10 41.4 9.5 2.4e-10 40.4 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 EER28202.1 - 3.1e-10 40.1 0.1 8.6e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EER28202.1 - 4e-06 26.5 6.9 8.1e-06 25.5 0.4 3.2 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase ALAD PF00490.21 EER28203.1 - 3.2e-120 401.1 0.0 3.7e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CIAPIN1 PF05093.13 EER28204.1 - 6.7e-42 142.1 3.0 9.9e-42 141.5 3.0 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EER28204.1 - 3.6e-36 124.3 0.0 5.3e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Nucleoporin_C PF03177.14 EER28205.1 - 1.6e-172 575.4 0.1 1.9e-172 575.1 0.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EER28205.1 - 1.6e-55 188.6 0.0 2.1e-55 188.3 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF5449 PF17528.2 EER28205.1 - 0.18 11.6 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5449) SHNi-TPR PF10516.9 EER28206.1 - 9.2e-17 60.2 0.6 6.7e-15 54.3 0.0 3.1 2 1 0 2 2 2 1 SHNi-TPR TPR_12 PF13424.6 EER28206.1 - 6.5e-05 23.1 3.1 0.032 14.5 1.7 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat PMBR PF09373.10 EER28206.1 - 0.011 15.8 0.0 0.04 14.1 0.0 2.0 1 0 0 1 1 1 0 Pseudomurein-binding repeat TPR_10 PF13374.6 EER28206.1 - 0.018 14.9 4.1 12 5.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EER28206.1 - 0.035 13.9 5.0 0.54 10.2 0.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat sCache_2 PF17200.4 EER28206.1 - 0.068 13.0 0.2 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Single Cache domain 2 TPR_16 PF13432.6 EER28206.1 - 0.093 13.4 3.7 2.2 9.0 0.7 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EER28206.1 - 0.17 12.2 6.6 8.9 6.8 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EER28206.1 - 0.25 11.1 1.6 31 4.4 1.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_2 PF07719.17 EER28206.1 - 3.1 8.1 17.0 5.9 7.3 0.8 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TBCA PF02970.16 EER28206.1 - 9.2 6.7 7.8 17 5.8 0.3 3.8 2 1 1 4 4 4 0 Tubulin binding cofactor A ATG7_N PF16420.5 EER28207.1 - 1.1e-103 347.0 0.0 1.5e-103 346.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EER28207.1 - 2.9e-42 144.7 0.0 4.5e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EER28207.1 - 0.19 11.8 0.1 0.58 10.2 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Thioredoxin PF00085.20 EER28208.1 - 1.6e-62 207.9 2.8 8.7e-31 106.0 0.1 4.1 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 EER28208.1 - 8.8e-48 162.6 4.9 6.2e-36 124.0 1.3 3.5 3 1 1 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.17 EER28208.1 - 7.4e-12 45.0 0.8 7.4e-12 45.0 0.8 1.6 2 0 0 2 2 2 1 Calsequestrin OST3_OST6 PF04756.13 EER28208.1 - 1.8e-08 34.1 0.2 0.00044 19.7 0.0 2.9 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EER28208.1 - 5.1e-08 33.0 0.0 0.0024 18.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EER28208.1 - 8.4e-08 32.6 0.3 0.025 15.0 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EER28208.1 - 3.7e-07 30.4 0.0 0.072 13.4 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 EER28208.1 - 7e-06 26.0 0.1 0.082 12.8 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 EER28208.1 - 0.0011 18.6 0.2 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 Redoxin Thioredoxin_4 PF13462.6 EER28208.1 - 0.072 13.2 2.5 7.7 6.6 0.0 3.6 3 0 0 3 3 3 0 Thioredoxin His_biosynth PF00977.21 EER28209.1 - 2.1e-46 158.2 0.3 7.9e-46 156.4 0.3 1.9 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EER28209.1 - 3.1e-22 79.3 0.0 4.6e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EER28209.1 - 1.5e-09 38.0 0.0 1.1e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EER28209.1 - 2.3e-09 37.2 0.0 4.9e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EER28209.1 - 0.01 15.6 0.1 0.25 11.1 0.1 2.2 2 0 0 2 2 2 0 Peptidase C26 DJ-1_PfpI PF01965.24 EER28209.1 - 0.084 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family DUF2156 PF09924.9 EER28209.1 - 0.17 10.9 0.0 7.6 5.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2156) SH3_1 PF00018.28 EER28209.1 - 0.35 10.5 1.2 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 SH3 domain HNH_2 PF13391.6 EER28210.1 - 5.1e-10 39.3 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Abi_2 PF07751.11 EER28210.1 - 0.096 12.9 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Abi-like protein UCH PF00443.29 EER28211.1 - 6.2e-36 124.2 0.0 9.8e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EER28211.1 - 1.8e-24 85.3 4.1 8.1e-24 83.2 0.3 2.6 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 EER28211.1 - 4.6e-21 74.9 23.2 4.2e-19 68.6 2.6 4.2 5 0 0 5 5 5 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EER28211.1 - 2.6e-18 65.6 0.0 8.1e-10 38.4 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 EER28211.1 - 2.4e-14 53.7 0.1 2.4e-14 53.7 0.1 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase dCMP_cyt_deam_1 PF00383.23 EER28213.1 - 7e-28 96.5 3.5 1.2e-27 95.7 3.5 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EER28213.1 - 1.1e-11 44.6 0.7 2e-11 43.8 0.7 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EER28213.1 - 0.016 15.8 0.0 0.084 13.4 0.0 2.1 1 1 1 2 2 2 0 AAA domain SNAD4 PF18750.1 EER28213.1 - 0.21 11.7 2.5 0.33 11.1 1.1 2.0 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 4 SAS4 PF15460.6 EER28214.1 - 3.6e-30 104.0 2.3 7.8e-30 102.9 2.3 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 RPN7 PF10602.9 EER28215.1 - 2e-50 170.9 0.7 4.4e-50 169.8 0.3 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EER28215.1 - 6.7e-09 36.2 1.3 2e-08 34.7 0.5 2.2 2 1 0 2 2 2 1 PCI domain DUF4349 PF14257.6 EER28215.1 - 0.064 12.7 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) MscS_porin PF12795.7 EER28215.1 - 0.082 12.4 0.1 0.13 11.8 0.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TPR_21 PF09976.9 EER28215.1 - 0.11 12.2 1.4 0.79 9.4 1.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 EER28215.1 - 0.24 11.3 1.5 28 4.7 0.1 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC_membrane PF00664.23 EER28216.1 - 1.3e-80 271.0 32.7 2.3e-42 145.5 10.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EER28216.1 - 1.1e-55 187.9 0.0 1.8e-26 93.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EER28216.1 - 8e-14 51.6 3.8 4.6e-05 23.0 0.0 4.5 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EER28216.1 - 1.2e-08 34.6 0.3 0.0021 17.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EER28216.1 - 4.4e-08 33.5 0.3 0.022 15.1 0.2 3.8 3 1 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EER28216.1 - 2.4e-06 27.6 0.2 0.43 10.4 0.1 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EER28216.1 - 6.6e-06 26.1 0.1 0.16 11.9 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EER28216.1 - 6.8e-06 26.6 2.3 0.089 13.2 0.0 3.6 3 1 0 3 3 2 2 AAA ATPase domain AAA_25 PF13481.6 EER28216.1 - 2.3e-05 24.1 0.0 1.1 8.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 EER28216.1 - 4.8e-05 22.3 1.0 0.36 9.6 0.1 3.6 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 EER28216.1 - 0.00018 22.1 1.1 0.12 12.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EER28216.1 - 0.00026 21.1 0.1 0.17 12.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF3987 PF13148.6 EER28216.1 - 0.0005 19.2 0.0 0.84 8.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_30 PF13604.6 EER28216.1 - 0.0013 18.5 0.1 2.3 7.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.17 EER28216.1 - 0.0036 17.4 1.8 1.7 8.7 0.1 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_15 PF13175.6 EER28216.1 - 0.0043 16.8 0.3 1.1 8.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EER28216.1 - 0.012 14.8 0.1 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 EER28216.1 - 0.019 15.1 0.3 6.2 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EER28216.1 - 0.028 13.8 0.1 5.2 6.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family PhoH PF02562.16 EER28216.1 - 0.031 13.7 0.4 4 6.8 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein AAA_5 PF07728.14 EER28216.1 - 0.048 13.6 0.0 13 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATPase PF06745.13 EER28216.1 - 0.096 12.0 2.4 3.1 7.1 0.0 2.8 3 0 0 3 3 3 0 KaiC IstB_IS21 PF01695.17 EER28216.1 - 0.1 12.3 0.1 9.3 5.9 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein T2SSE PF00437.20 EER28216.1 - 0.1 11.6 0.1 6.2 5.8 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.6 EER28216.1 - 0.13 12.8 3.0 18 5.8 0.3 3.3 3 1 0 3 3 3 0 AAA domain APS_kinase PF01583.20 EER28216.1 - 0.16 11.8 0.0 26 4.7 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Zeta_toxin PF06414.12 EER28216.1 - 0.17 11.1 0.1 22 4.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EER28216.1 - 0.18 11.5 0.1 5.3 6.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EER28216.1 - 0.18 12.1 0.8 1.9 8.8 0.1 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AIG1 PF04548.16 EER28216.1 - 1 8.6 2.3 5.8 6.2 0.1 2.8 4 0 0 4 4 2 0 AIG1 family OTT_1508_deam PF14441.6 EER28217.1 - 1.6e-17 63.3 0.2 3e-17 62.4 0.2 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase CHAD PF05235.14 EER28217.1 - 0.0055 16.7 0.9 0.4 10.6 0.1 2.3 2 0 0 2 2 2 2 CHAD domain Kdo PF06293.14 EER28219.1 - 0.00032 20.1 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EER28219.1 - 0.0019 17.6 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain FTA2 PF13095.6 EER28219.1 - 0.0081 15.8 0.4 0.035 13.7 0.4 2.2 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 DUF5478 PF17572.2 EER28219.1 - 0.039 14.1 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5478) DUF3377 PF11857.8 EER28220.1 - 0.016 15.1 0.1 0.042 13.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RSN1_TM PF13967.6 EER28220.1 - 0.11 12.3 0.4 0.2 11.4 0.4 1.4 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Herpes_glycop PF01528.16 EER28220.1 - 0.19 10.5 0.1 0.31 9.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein M TMEM132D_C PF15706.5 EER28220.1 - 0.21 11.4 0.0 2.1 8.2 0.0 2.2 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Orf78 PF06024.12 EER28220.1 - 0.21 11.9 0.1 0.55 10.6 0.1 1.6 1 0 0 1 1 1 0 Orf78 (ac78) 7tm_2 PF00002.24 EER28220.1 - 0.29 10.4 0.9 0.44 9.8 0.9 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) RIFIN PF02009.16 EER28220.1 - 0.37 10.6 0.9 0.83 9.5 0.2 1.8 2 0 0 2 2 2 0 Rifin DUF4083 PF13314.6 EER28220.1 - 0.46 10.5 2.2 0.98 9.4 2.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) BatA PF07584.11 EER28220.1 - 3.1 8.2 5.2 0.71 10.3 0.5 2.3 2 1 1 3 3 3 0 Aerotolerance regulator N-terminal adh_short PF00106.25 EER28221.1 - 5.1e-31 107.6 0.0 8.8e-31 106.9 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER28221.1 - 5.8e-26 91.5 0.0 1.8e-25 89.9 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TPP_enzyme_C PF02775.21 EER28222.1 - 2.6e-25 89.0 0.0 5.6e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EER28222.1 - 3e-24 85.3 0.0 4.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.18 EER28222.1 - 1.7e-21 76.6 0.0 9.5e-21 74.2 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF498 PF04430.14 EER28222.1 - 0.014 15.5 0.0 0.042 13.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Cep57_MT_bd PF06657.13 EER28223.1 - 1.8e-27 95.6 0.7 1.8e-27 95.6 0.7 3.0 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EER28223.1 - 2.1e-19 69.3 3.4 2.1e-19 69.3 3.4 3.7 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 HALZ PF02183.18 EER28223.1 - 0.00058 20.0 0.9 0.00058 20.0 0.9 3.6 3 1 0 3 3 3 2 Homeobox associated leucine zipper ZapB PF06005.12 EER28223.1 - 0.014 15.8 8.1 0.014 15.8 8.1 4.2 5 0 0 5 5 5 0 Cell division protein ZapB YabA PF06156.13 EER28223.1 - 0.59 10.8 24.1 1.8 9.2 5.5 5.2 3 2 2 5 5 5 0 Initiation control protein YabA MAT1 PF06391.13 EER28224.1 - 5e-44 150.6 8.5 6.4e-44 150.2 8.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EER28224.1 - 6e-32 109.3 8.5 9e-32 108.7 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER28224.1 - 0.00023 20.9 3.1 0.00064 19.5 3.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER28224.1 - 0.00049 19.9 5.1 0.00084 19.1 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER28224.1 - 0.00056 19.7 4.1 0.0011 18.7 4.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER28224.1 - 0.0066 16.8 6.6 0.012 16.0 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 EER28224.1 - 0.042 13.5 1.9 0.084 12.5 1.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EER28224.1 - 0.075 13.0 8.2 2.5 8.1 9.2 2.3 1 1 1 2 2 2 0 zinc-RING finger domain DUF3797 PF12677.7 EER28224.1 - 0.14 12.1 1.6 0.29 11.0 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) DUF5338 PF17273.2 EER28224.1 - 0.16 12.1 4.1 23 5.1 0.3 3.6 4 0 0 4 4 3 0 Family of unknown function (DUF5338) zf-RING_4 PF14570.6 EER28224.1 - 0.17 11.7 6.2 0.66 9.8 2.4 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EER28224.1 - 0.26 11.4 6.4 0.53 10.4 6.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EER28224.1 - 3.8 7.5 8.2 1.3e+02 2.5 0.2 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Presenilin PF01080.17 EER28224.1 - 4 6.1 4.0 5.5 5.7 4.0 1.1 1 0 0 1 1 1 0 Presenilin Iron_permease PF04120.12 EER28225.1 - 0.046 13.5 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 Low affinity iron permease HRXXH PF13933.6 EER28226.1 - 2.7e-101 338.2 0.0 3.2e-101 338.0 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EER28226.1 - 0.0095 16.5 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Zip PF02535.22 EER28227.1 - 8.6e-43 146.8 21.0 1.4e-41 142.8 21.0 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.12 EER28227.1 - 0.00018 21.0 9.5 0.00089 18.8 1.5 2.6 2 0 0 2 2 2 2 HupE / UreJ protein MGC-24 PF05283.11 EER28227.1 - 0.5 10.8 6.0 3.9 7.9 2.7 2.3 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Prefoldin_3 PF13758.6 EER28228.1 - 7e-36 122.3 2.1 7e-36 122.3 2.1 2.2 3 1 0 3 3 3 1 Prefoldin subunit DUF3835 PF12927.7 EER28228.1 - 3.7e-24 85.4 0.6 3.7e-24 85.4 0.6 4.0 5 0 0 5 5 5 2 Domain of unknown function (DUF3835) MerR-DNA-bind PF09278.11 EER28228.1 - 0.0016 18.9 1.4 2.5 8.7 0.1 2.7 2 0 0 2 2 2 2 MerR, DNA binding CENP-F_leu_zip PF10473.9 EER28228.1 - 8.9 6.3 8.1 27 4.8 0.5 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.25 EER28229.1 - 4.2e-41 141.1 0.0 1.3e-40 139.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER28229.1 - 5.2e-28 98.0 0.0 8.4e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER28229.1 - 2.3e-06 27.2 0.0 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EER28229.1 - 0.0015 17.3 0.0 0.0024 16.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EER28229.1 - 0.027 13.8 0.0 0.15 11.4 0.0 2.1 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family NGP1NT PF08153.12 EER28230.1 - 1.4e-50 170.8 0.1 2.3e-50 170.1 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EER28230.1 - 3.6e-17 62.5 0.0 1.9e-13 50.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EER28230.1 - 7.9e-06 25.5 0.0 8.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EER28230.1 - 0.00063 19.7 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EER28230.1 - 0.00071 19.1 0.0 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 EER28230.1 - 0.0022 18.1 0.1 0.82 9.7 0.0 3.3 2 1 1 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 EER28230.1 - 0.0092 15.5 0.0 0.77 9.3 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EER28230.1 - 0.099 12.9 0.1 25 5.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 EER28232.1 - 1.6e-48 164.8 0.0 1.3e-47 161.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER28232.1 - 1.4e-28 99.5 0.5 1.1e-27 96.6 0.1 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER28232.1 - 0.0024 17.9 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 EER28232.1 - 0.036 13.8 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF2040 PF09745.9 EER28232.1 - 3.5 7.7 7.6 1.8 8.7 1.1 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Suf PF05843.14 EER28233.1 - 0.00025 21.1 6.8 0.013 15.5 0.0 3.7 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) c-SKI_SMAD_bind PF08782.10 EER28233.1 - 0.024 14.8 1.6 3.4 7.9 0.0 3.6 2 1 1 3 3 3 0 c-SKI Smad4 binding domain TPR_14 PF13428.6 EER28233.1 - 0.033 15.0 6.5 0.65 11.0 0.1 5.5 8 1 1 9 9 9 0 Tetratricopeptide repeat Mitoc_mL59 PF18126.1 EER28234.1 - 2.7e-50 170.0 1.8 3.7e-50 169.6 1.8 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 MOSC PF03473.17 EER28235.1 - 1.9e-36 124.9 0.1 3.4e-36 124.2 0.1 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EER28235.1 - 4.5e-26 91.1 0.0 2.2e-25 88.9 0.0 2.1 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 EER28235.1 - 3.8e-21 75.4 0.0 1.1e-20 74.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V MARVEL PF01284.23 EER28236.1 - 0.0064 16.5 14.0 0.0087 16.1 14.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF1980 PF09323.10 EER28236.1 - 0.15 12.0 3.0 2.7 7.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) HemY_N PF07219.13 EER28236.1 - 9 6.5 7.3 27 5.0 0.1 2.5 2 1 0 2 2 2 0 HemY protein N-terminus PAP2 PF01569.21 EER28237.1 - 2.4e-28 98.6 0.3 5.7e-28 97.4 0.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EER28237.1 - 0.00014 21.6 0.7 0.00052 19.8 0.6 2.1 1 1 0 1 1 1 1 PAP2 superfamily PBP1_TM PF14812.6 EER28237.1 - 0.65 10.4 4.3 19 5.7 0.4 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal But2 PF09792.9 EER28238.1 - 4.4e-52 176.2 1.2 5.4e-52 176.0 1.2 1.1 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain bZIP_2 PF07716.15 EER28239.1 - 1.3e-05 25.2 8.6 1.8e-05 24.7 8.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EER28239.1 - 0.041 14.4 5.8 0.07 13.7 5.8 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.21 EER28239.1 - 0.072 13.2 7.0 0.12 12.5 7.0 1.2 1 0 0 1 1 1 0 bZIP transcription factor FlaG PF03646.15 EER28239.1 - 0.41 10.8 1.9 0.73 10.0 1.9 1.3 1 0 0 1 1 1 0 FlaG protein FB_lectin PF07367.11 EER28240.1 - 1.9e-05 24.6 0.0 0.049 13.6 0.0 2.3 2 0 0 2 2 2 2 Fungal fruit body lectin Sterol_MT_C PF08498.10 EER28241.1 - 4.4e-30 103.8 0.2 7.4e-30 103.1 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_25 PF13649.6 EER28241.1 - 3.5e-16 59.7 0.0 6.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER28241.1 - 5.8e-16 58.9 0.0 1e-15 58.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER28241.1 - 3.7e-14 52.8 0.0 5.4e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER28241.1 - 4.6e-12 46.1 0.0 7.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EER28241.1 - 7.2e-11 41.9 0.0 9.9e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EER28241.1 - 3.3e-10 40.6 0.0 7.9e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EER28241.1 - 1.2e-07 31.3 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EER28241.1 - 0.0032 17.2 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EER28241.1 - 0.0075 15.7 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 EER28241.1 - 0.0093 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER28241.1 - 0.015 14.9 0.0 0.046 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.10 EER28241.1 - 0.022 14.4 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 EER28241.1 - 0.061 12.6 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 EER28241.1 - 0.064 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.20 EER28241.1 - 0.27 10.3 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RRM_1 PF00076.22 EER28242.1 - 5.6e-08 32.5 0.0 9.8e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EER28242.1 - 0.045 13.8 0.0 0.072 13.1 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.15 EER28243.1 - 0.003 17.6 0.2 0.0059 16.6 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RAC_head PF16717.5 EER28244.1 - 1.6e-29 102.7 6.5 1.6e-29 102.7 6.5 3.1 3 1 1 4 4 4 1 Ribosome-associated complex head domain DnaJ PF00226.31 EER28244.1 - 1.5e-17 63.5 0.8 4.4e-17 61.9 0.8 1.9 1 0 0 1 1 1 1 DnaJ domain Sulfatase PF00884.23 EER28245.1 - 1e-57 195.9 0.1 1.3e-57 195.5 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EER28245.1 - 4.9e-22 77.5 0.2 1.3e-21 76.1 0.1 1.8 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EER28245.1 - 1.1e-08 35.1 0.0 9.2e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EER28245.1 - 0.0032 18.2 0.1 0.011 16.5 0.1 1.9 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.12 EER28245.1 - 0.024 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.17 EER28245.1 - 0.056 12.0 0.0 0.081 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Amidohydro_1 PF01979.20 EER28246.1 - 1.1e-69 235.4 0.0 1.4e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EER28246.1 - 3.3e-10 40.1 0.2 2.3e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EER28246.1 - 0.0069 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase GDC-P PF02347.16 EER28247.1 - 1.3e-176 587.7 0.1 4.5e-164 546.4 0.0 3.2 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EER28247.1 - 6.3e-08 32.2 0.0 2.1e-07 30.5 0.1 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EER28247.1 - 0.0031 16.9 0.0 0.0052 16.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Retrotran_gag_2 PF14223.6 EER28248.1 - 0.0001 22.0 0.1 0.00017 21.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Pyridoxal_deC PF00282.19 EER28249.1 - 3.9e-101 338.5 0.0 4.8e-101 338.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain bZIP_2 PF07716.15 EER28250.1 - 6.4e-09 35.8 17.0 6.4e-09 35.8 17.0 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EER28250.1 - 8.9e-07 28.9 17.5 2.1e-06 27.7 17.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EER28250.1 - 0.00055 20.4 14.0 0.0014 19.1 14.0 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF3450 PF11932.8 EER28250.1 - 0.0035 16.7 5.9 0.0065 15.8 5.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) APG6_N PF17675.1 EER28250.1 - 0.03 14.8 12.9 0.059 13.9 12.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region FPP PF05911.11 EER28250.1 - 0.055 11.7 7.4 0.078 11.2 7.4 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil DUF4404 PF14357.6 EER28250.1 - 1.4 9.6 7.2 2.4 8.8 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) Caps_synth_GfcC PF06251.11 EER28250.1 - 1.6 8.3 3.9 16 5.1 2.7 2.1 2 0 0 2 2 2 0 Capsule biosynthesis GfcC DUF3347 PF11827.8 EER28251.1 - 1.3 9.1 9.2 3.3 7.8 4.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Uso1_p115_C PF04871.13 EER28251.1 - 8.1 6.8 14.9 2.5 8.5 3.3 2.3 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Amidase PF01425.21 EER28253.1 - 5.8e-119 398.0 0.2 1e-118 397.2 0.2 1.3 1 1 0 1 1 1 1 Amidase Bystin PF05291.11 EER28255.1 - 5.6e-131 436.1 0.0 8.9e-131 435.5 0.0 1.3 1 0 0 1 1 1 1 Bystin Actin PF00022.19 EER28256.1 - 1.8e-23 82.8 0.0 9.6e-20 70.6 0.0 2.5 3 0 0 3 3 3 2 Actin CBFD_NFYB_HMF PF00808.23 EER28257.1 - 9.8e-19 67.4 0.5 9.8e-19 67.4 0.5 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EER28257.1 - 1e-06 29.1 0.9 2.5e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Lipase_chap PF03280.14 EER28257.1 - 0.0068 16.4 0.8 0.0088 16.0 0.8 1.1 1 0 0 1 1 1 1 Proteobacterial lipase chaperone protein YolD PF08863.10 EER28257.1 - 0.0091 16.0 3.7 0.0091 16.0 3.7 1.6 2 0 0 2 2 2 1 YolD-like protein Bromo_TP PF07524.13 EER28257.1 - 0.039 14.0 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.15 EER28257.1 - 0.054 13.6 0.0 0.079 13.0 0.0 1.3 1 1 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit adh_short PF00106.25 EER28258.1 - 1.6e-42 145.2 0.1 1.9e-42 145.0 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER28258.1 - 8e-30 104.1 0.0 9.2e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER28258.1 - 2.8e-08 33.9 0.0 4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EER28258.1 - 0.0047 16.8 0.1 0.018 15.0 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H-binding Multi_Drug_Res PF00893.19 EER28258.1 - 0.031 15.0 0.3 0.053 14.2 0.3 1.3 1 0 0 1 1 1 0 Small Multidrug Resistance protein TrkA_N PF02254.18 EER28258.1 - 0.068 13.4 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain Clathrin_propel PF01394.20 EER28258.1 - 0.21 12.0 0.3 1.4 9.3 0.0 2.5 4 0 0 4 4 4 0 Clathrin propeller repeat DAO PF01266.24 EER28259.1 - 2.9e-42 145.5 0.0 3.4e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER28259.1 - 0.00042 20.5 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EER28259.1 - 0.00057 20.4 0.0 0.044 14.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER28259.1 - 0.0016 17.8 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER28259.1 - 0.044 13.8 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding SMC_Nse1 PF07574.13 EER28260.1 - 6.1e-73 244.9 0.8 7.2e-73 244.6 0.8 1.0 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex CtsR_C PF17727.1 EER28260.1 - 0.00032 20.8 0.4 0.5 10.5 0.0 3.1 3 0 0 3 3 3 2 CtsR C-terminal dimerization domain YabA PF06156.13 EER28260.1 - 0.021 15.5 0.1 0.045 14.4 0.1 1.5 1 0 0 1 1 1 0 Initiation control protein YabA DUF2161 PF09929.9 EER28260.1 - 0.038 14.1 0.1 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) Glyco_hydro_65N PF03636.15 EER28261.1 - 3e-33 115.4 0.0 4.5e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 EER28261.1 - 9.3e-24 84.0 0.8 4e-18 65.4 0.2 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 EER28261.1 - 0.0033 17.3 0.2 0.0079 16.1 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Beta-lactamase PF00144.24 EER28262.1 - 1.2e-33 116.8 0.0 2e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EER28262.1 - 0.0017 17.9 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 D-alanyl-D-alanine carboxypeptidase ADH_zinc_N PF00107.26 EER28263.1 - 3.5e-17 62.6 0.0 5.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER28263.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain KR PF08659.10 EER28263.1 - 0.036 14.0 0.1 0.056 13.3 0.1 1.2 1 0 0 1 1 1 0 KR domain POTRA PF07244.15 EER28263.1 - 0.17 12.5 0.3 20 5.9 0.0 2.7 2 1 0 2 2 2 0 Surface antigen variable number repeat Metallophos PF00149.28 EER28264.1 - 4.4e-10 40.4 2.5 8.4e-10 39.5 2.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EER28264.1 - 0.004 17.4 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 EER28265.1 - 3.5e-46 157.1 0.0 5.6e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EER28265.1 - 3.5e-33 114.1 0.0 8.9e-33 112.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain zf-C2H2_jaz PF12171.8 EER28266.1 - 0.00077 19.7 4.3 0.0012 19.1 4.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EER28266.1 - 0.0015 18.8 1.8 0.003 17.9 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.7 EER28266.1 - 0.004 17.5 0.7 0.0067 16.8 0.7 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 EER28266.1 - 0.039 13.9 0.3 0.064 13.2 0.3 1.3 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 EER28266.1 - 0.07 14.0 0.8 0.16 12.9 0.8 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EER28266.1 - 0.095 13.0 0.2 0.14 12.5 0.2 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GRP PF07172.11 EER28266.1 - 0.46 11.2 18.4 0.21 12.3 11.1 2.2 2 0 0 2 2 2 0 Glycine rich protein family Herpes_capsid PF06112.11 EER28266.1 - 0.54 10.3 4.3 0.99 9.5 4.3 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1691 PF07950.11 EER28267.1 - 6.7e-43 145.8 6.5 2.6e-33 114.9 5.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Ste5 PF11610.8 EER28267.1 - 0.086 12.7 4.5 0.12 12.3 0.6 2.3 2 0 0 2 2 2 0 Scaffold protein Ste5, Fus3-binding region APH PF01636.23 EER28268.1 - 0.00075 19.5 0.1 0.0054 16.7 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF5618 PF18498.1 EER28268.1 - 0.042 14.0 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5618) PI3_PI4_kinase PF00454.27 EER28268.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Membrane_bind PF14564.6 EER28269.1 - 3.2e-34 117.7 0.0 5.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.10 EER28269.1 - 1.2e-05 25.4 0.1 3.4e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Beta/Gamma crystallin Erythro_esteras PF05139.14 EER28269.1 - 0.042 13.7 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Erythromycin esterase TRM PF02005.16 EER28270.1 - 4.7e-112 374.9 0.0 5.8e-97 325.2 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EER28270.1 - 0.00023 21.0 0.0 0.00042 20.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 EER28270.1 - 0.16 12.7 0.0 0.34 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EER28270.1 - 0.18 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Iso_dh PF00180.20 EER28271.1 - 3.6e-107 358.5 0.0 4.2e-107 358.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FAS_I_H PF18314.1 EER28272.1 - 1e-79 266.9 2.3 1.1e-79 266.8 0.0 2.2 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EER28272.1 - 4.8e-75 251.3 0.0 9.3e-75 250.4 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EER28272.1 - 1.4e-19 70.7 0.0 2.7e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EER28272.1 - 7.2e-19 68.0 0.0 1.7e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EER28272.1 - 1.8e-11 44.1 0.0 5.7e-11 42.5 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EER28272.1 - 0.0017 18.3 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EER28272.1 - 0.026 15.1 0.1 0.11 13.0 0.1 2.1 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 4PPT_N PF17837.1 EER28272.1 - 0.71 10.0 3.0 4.3 7.5 3.0 2.3 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain DUF1729 PF08354.10 EER28273.1 - 1.1e-161 537.6 0.0 1.6e-161 537.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EER28273.1 - 1.6e-93 313.7 0.0 1.1e-90 304.4 0.0 3.0 3 0 0 3 3 3 2 Acyl transferase domain FAS_meander PF17951.1 EER28273.1 - 1.2e-55 187.3 0.0 3.3e-55 185.9 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EER28273.1 - 2.7e-40 137.4 0.0 1.8e-39 134.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydratas PF01575.19 EER28273.1 - 7.9e-39 132.0 0.2 2e-38 130.7 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain SAT PF16073.5 EER28273.1 - 3.2e-38 131.8 0.0 9.5e-38 130.3 0.0 1.8 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydrat_N PF13452.6 EER28273.1 - 1.1e-20 74.1 0.0 3.3e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MCRS_N PF13325.6 EER28273.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein TFIIF_alpha PF05793.12 EER28274.1 - 3.4e-11 42.4 52.8 3.4e-11 42.4 52.8 3.5 2 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.19 EER28275.1 - 5.5e-18 64.9 0.2 1.4e-17 63.6 0.2 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase PAP_central PF04928.17 EER28275.1 - 0.034 13.1 0.2 0.1 11.6 0.1 1.7 2 0 0 2 2 2 0 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 EER28275.1 - 0.054 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF642 PF04862.12 EER28275.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF642) Rep-A_N PF04057.12 EER28276.1 - 0.0024 17.9 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain REPA_OB_2 PF16900.5 EER28276.1 - 0.003 17.4 0.0 0.026 14.4 0.0 2.3 1 1 0 1 1 1 1 Replication protein A OB domain DUF383 PF04063.14 EER28277.1 - 7.5e-68 228.0 0.3 6.4e-67 224.9 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EER28277.1 - 5.9e-22 77.3 0.9 1.6e-21 75.8 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Mic1 PF07035.12 EER28277.1 - 0.022 14.5 0.3 0.045 13.5 0.3 1.4 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Methyltransf_23 PF13489.6 EER28278.1 - 6.3e-11 42.4 0.0 9.8e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER28278.1 - 1.6e-05 25.5 0.0 4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER28278.1 - 0.00073 20.1 0.0 0.0021 18.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER28278.1 - 0.0032 18.2 0.0 0.0092 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER28278.1 - 0.032 14.0 0.0 0.09 12.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Inositol_P PF00459.25 EER28279.1 - 2.4e-69 233.9 0.0 2.7e-69 233.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family IBR PF01485.21 EER28280.1 - 6.2e-12 45.6 47.6 4.3e-07 30.0 12.1 3.6 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain DUF2158 PF09926.9 EER28280.1 - 0.015 15.0 0.2 0.029 14.1 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) zf-CCHC PF00098.23 EER28280.1 - 0.05 13.7 0.6 0.05 13.7 0.6 3.6 3 0 0 3 3 3 0 Zinc knuckle DUF676 PF05057.14 EER28281.1 - 2.1e-40 138.6 0.0 7e-27 94.4 0.0 3.2 2 1 0 2 2 2 2 Putative serine esterase (DUF676) PGAP1 PF07819.13 EER28281.1 - 0.18 11.5 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 EER28281.1 - 0.21 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DAGK_cat PF00781.24 EER28283.1 - 1.8e-11 43.8 0.0 3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain His_Phos_2 PF00328.22 EER28284.1 - 5.6e-112 374.9 0.0 7.3e-112 374.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EER28284.1 - 7e-38 128.7 0.0 1.6e-37 127.5 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EER28284.1 - 9e-07 28.7 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 EER28285.1 - 5.8e-82 274.7 0.0 8.9e-82 274.1 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EER28285.1 - 1e-16 61.0 24.6 6.7e-05 23.6 0.9 9.7 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER28285.1 - 2.6e-12 46.9 0.0 0.0051 17.1 0.0 6.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER28285.1 - 0.066 11.8 0.1 9 4.8 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin Nup120/160 HPS3_N PF14761.6 EER28285.1 - 0.21 11.1 0.0 0.54 9.8 0.0 1.6 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 XPG_I_2 PF12813.7 EER28287.1 - 6.6e-84 281.3 0.0 9.3e-84 280.8 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc_N PF02739.16 EER28287.1 - 0.013 15.4 0.0 0.069 13.0 0.0 2.0 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain XPG_I PF00867.18 EER28287.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.5 1 0 0 1 1 1 0 XPG I-region adh_short_C2 PF13561.6 EER28288.1 - 6.6e-59 199.3 0.5 7.4e-59 199.1 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER28288.1 - 7.4e-47 159.3 0.8 9.7e-47 159.0 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EER28288.1 - 0.018 14.9 0.3 0.032 14.1 0.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NanE PF04131.14 EER28288.1 - 0.055 12.7 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase HET PF06985.11 EER28290.1 - 9.9e-34 116.8 0.1 5.1e-33 114.5 0.1 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fcf1 PF04900.12 EER28291.1 - 3.1e-38 130.2 1.6 4.8e-38 129.5 0.7 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EER28291.1 - 1.4e-11 44.8 0.1 2.2e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 PIN like domain Fringe PF02434.16 EER28292.1 - 1.8e-06 27.6 0.2 4.8e-05 22.9 0.2 2.4 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 EER28292.1 - 0.0014 18.1 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_1 PF00024.26 EER28292.1 - 0.004 17.1 1.6 0.0075 16.2 1.6 1.4 1 0 0 1 1 1 1 PAN domain PAN_2 PF08276.11 EER28292.1 - 0.0091 16.1 0.3 0.019 15.1 0.3 1.5 1 0 0 1 1 1 1 PAN-like domain FAE1_CUT1_RppA PF08392.12 EER28292.1 - 0.24 10.7 0.0 0.38 10.0 0.0 1.2 1 0 0 1 1 1 0 FAE1/Type III polyketide synthase-like protein Glyco_transf_34 PF05637.12 EER28292.1 - 0.31 10.7 4.5 0.27 10.9 2.5 1.7 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family GFA PF04828.14 EER28293.1 - 1.9e-11 44.1 0.6 3.6e-07 30.4 0.1 2.3 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme RVT_2 PF07727.14 EER28295.1 - 2e-50 171.7 0.0 3.1e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EER28295.1 - 1.7e-14 54.0 0.0 8.9e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EER28295.1 - 4.2e-06 26.5 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 EER28295.1 - 0.001 19.0 1.7 0.0022 18.0 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 EER28295.1 - 0.0084 15.8 0.1 0.0084 15.8 0.1 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 EER28295.1 - 0.082 12.7 0.1 2.8 7.8 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain Neugrin PF06413.11 EER28295.1 - 0.15 12.0 6.5 0.34 10.9 5.2 2.3 2 0 0 2 2 2 0 Neugrin Ras PF00071.22 EER28296.1 - 8.8e-65 217.2 0.0 1.1e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER28296.1 - 2.6e-33 114.8 0.0 4.5e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER28296.1 - 4.1e-13 49.1 0.0 5.3e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EER28296.1 - 0.00012 21.7 0.0 0.00029 20.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EER28296.1 - 0.00036 20.0 0.0 0.00063 19.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EER28296.1 - 0.00046 20.1 0.3 0.43 10.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EER28296.1 - 0.0071 16.4 0.0 0.016 15.2 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EER28296.1 - 0.095 12.2 0.0 0.33 10.5 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B NCA2 PF08637.10 EER28297.1 - 2.5e-103 345.3 0.0 3.8e-103 344.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 EER28298.1 - 1.2e-25 90.4 16.9 1.2e-25 90.4 16.9 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.19 EER28299.1 - 2.4e-28 98.1 0.1 3e-28 97.8 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase AAA PF00004.29 EER28300.1 - 3.1e-61 205.6 0.0 2e-41 141.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER28300.1 - 1.4e-19 69.6 1.1 8.8e-13 47.8 0.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EER28300.1 - 9.8e-08 32.6 8.8 0.059 13.8 0.1 4.9 3 2 1 5 5 5 2 AAA ATPase domain AAA_5 PF07728.14 EER28300.1 - 6.8e-07 29.4 0.8 0.0046 17.0 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EER28300.1 - 5.9e-06 26.6 0.0 0.023 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.18 EER28300.1 - 4.5e-05 23.4 0.0 0.00059 19.8 0.0 2.4 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.6 EER28300.1 - 5.3e-05 23.5 6.7 2.4 8.4 0.1 4.8 2 2 3 5 5 5 2 AAA domain Vps4_C PF09336.10 EER28300.1 - 0.00024 21.0 0.0 0.0043 17.0 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 EER28300.1 - 0.0005 19.4 0.3 0.0077 15.5 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 EER28300.1 - 0.00065 19.5 0.0 0.091 12.5 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EER28300.1 - 0.00068 19.2 0.5 0.72 9.3 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 EER28300.1 - 0.0016 18.4 0.0 0.53 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EER28300.1 - 0.0021 18.0 0.2 0.0065 16.4 0.1 1.8 2 1 0 2 2 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 EER28300.1 - 0.0024 18.3 0.0 1.8 9.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 EER28300.1 - 0.0025 17.4 5.3 1.7 8.2 0.0 4.0 2 2 2 4 4 4 1 AAA domain DUF815 PF05673.13 EER28300.1 - 0.0034 16.6 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 EER28300.1 - 0.0037 17.2 2.4 1.5 8.8 0.3 3.6 2 2 1 3 3 3 1 NACHT domain IstB_IS21 PF01695.17 EER28300.1 - 0.0054 16.5 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EER28300.1 - 0.0081 16.3 0.0 0.052 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EER28300.1 - 0.011 15.5 1.7 0.38 10.4 0.3 3.0 4 0 0 4 4 3 0 AAA domain Mg_chelatase PF01078.21 EER28300.1 - 0.017 14.5 0.6 0.34 10.2 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EER28300.1 - 0.021 14.8 0.4 1.6 8.6 0.1 3.0 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea CDC48_N PF02359.18 EER28300.1 - 0.026 14.7 0.0 0.072 13.3 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain AAA_11 PF13086.6 EER28300.1 - 0.031 14.1 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EER28300.1 - 0.055 14.0 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EER28300.1 - 0.069 12.9 0.4 7.3 6.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EER28300.1 - 0.086 12.2 0.0 4.1 6.8 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein MCM PF00493.23 EER28300.1 - 0.14 11.3 0.0 4.8 6.2 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain AAA_33 PF13671.6 EER28300.1 - 0.14 12.4 0.0 17 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EER28300.1 - 0.15 12.1 0.1 25 4.9 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EER28300.1 - 0.15 12.6 0.0 5.4 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EER28300.1 - 0.28 11.7 0.7 23 5.5 0.1 3.0 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 EER28300.1 - 0.29 11.5 1.5 28 5.0 0.0 2.9 3 1 0 3 3 2 0 AAA domain PI3_PI4_kinase PF00454.27 EER28301.1 - 1e-50 172.9 0.0 1.9e-50 172.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EER28301.1 - 7.4e-39 133.9 3.0 8.5e-39 133.7 1.8 1.8 2 0 0 2 2 2 1 FAT domain UME PF08064.13 EER28301.1 - 5.6e-34 116.1 3.1 1e-33 115.2 0.8 2.8 2 1 1 3 3 3 1 UME (NUC010) domain FATC PF02260.20 EER28301.1 - 1.2e-14 53.8 0.0 2.6e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.6 EER28301.1 - 0.015 16.0 3.1 0.76 10.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3385 PF11865.8 EER28301.1 - 0.017 15.0 0.7 0.2 11.6 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) TPR_7 PF13176.6 EER28301.1 - 0.053 13.6 0.1 75 3.7 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LtuB PF17455.2 EER28301.1 - 0.096 13.3 0.1 0.35 11.5 0.1 1.9 1 0 0 1 1 1 0 Late transcription unit B dCMP_cyt_deam_1 PF00383.23 EER28302.1 - 8.2e-26 89.8 0.0 1.2e-25 89.3 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EER28302.1 - 1.3e-21 76.8 0.0 1.7e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EER28302.1 - 0.0046 17.0 0.3 0.029 14.5 0.3 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase XOO_2897-deam PF14440.6 EER28302.1 - 0.028 14.5 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase SNAD4 PF18750.1 EER28302.1 - 0.056 13.6 0.0 0.092 12.9 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EER28302.1 - 0.17 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 NADH_u_ox_C PF12853.7 EER28303.1 - 8e-28 96.3 0.1 1.1e-27 95.8 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 EER28303.1 - 7.8e-26 90.6 0.1 2.2e-25 89.1 0.0 1.7 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.12 EER28304.1 - 5.5e-33 112.8 0.7 1e-32 111.9 0.7 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 SPT2 PF08243.11 EER28304.1 - 4 8.0 5.9 3.2 8.3 0.3 3.1 3 2 0 3 3 3 0 SPT2 chromatin protein RCC1 PF00415.18 EER28305.1 - 1.3e-61 205.0 4.3 9.2e-11 42.2 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EER28305.1 - 9e-41 136.9 27.2 7.9e-09 35.1 0.2 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Hira PF07569.11 EER28305.1 - 0.11 12.2 0.0 39 3.9 0.0 3.6 4 0 0 4 4 4 0 TUP1-like enhancer of split Cyclase PF04199.13 EER28306.1 - 1.3e-11 44.9 0.0 1.7e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase RibD_C PF01872.17 EER28307.1 - 4.1e-31 108.4 0.0 8.8e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 RibD C-terminal domain Nic96 PF04097.14 EER28308.1 - 1.5e-224 747.1 0.4 2e-224 746.7 0.4 1.0 1 0 0 1 1 1 1 Nup93/Nic96 RLAN PF14401.6 EER28308.1 - 0.17 11.6 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 RimK-like ATPgrasp N-terminal domain COX16 PF14138.6 EER28309.1 - 3.4e-22 78.8 0.0 4.6e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Y_phosphatase PF00102.27 EER28310.1 - 8e-61 205.6 0.0 1.2e-60 205.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EER28310.1 - 3.4e-11 43.6 0.0 2.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 EER28310.1 - 0.022 14.6 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain F-box PF00646.33 EER28311.1 - 5.1e-06 26.2 0.8 1.2e-05 25.1 0.8 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 EER28311.1 - 0.00014 21.8 0.6 0.00035 20.5 0.2 1.9 2 0 0 2 2 2 1 F-box-like domain F-box-like PF12937.7 EER28311.1 - 0.00065 19.5 1.5 0.0015 18.3 1.5 1.6 1 0 0 1 1 1 1 F-box-like Dynamin_N PF00350.23 EER28312.1 - 1.5e-36 126.0 0.1 2.7e-36 125.2 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EER28312.1 - 1.8e-25 89.7 0.0 3.5e-25 88.8 0.0 1.5 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 EER28312.1 - 6.8e-05 22.9 0.1 0.00066 19.7 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EER28312.1 - 0.00044 20.2 0.0 0.34 10.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EER28312.1 - 0.005 16.5 0.1 0.81 9.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain DUF2478 PF10649.9 EER28312.1 - 0.0078 15.8 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2478) Type2_restr_D3 PF16902.5 EER28312.1 - 0.14 12.1 0.2 2.2 8.2 0.1 2.5 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain FGGY_C PF02782.16 EER28314.1 - 4.8e-53 179.8 0.1 7.5e-53 179.2 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EER28314.1 - 2.1e-22 79.9 0.0 6.8e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain DUF5548 PF17702.1 EER28314.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5548) BcrAD_BadFG PF01869.20 EER28314.1 - 0.035 13.6 0.0 0.08 12.4 0.0 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 EER28314.1 - 1.8 8.4 4.2 4 7.3 0.3 2.7 3 0 0 3 3 3 0 Transposase Na_Ca_ex PF01699.24 EER28315.1 - 5.3e-22 78.4 36.1 1.6e-14 54.2 12.9 3.2 4 0 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EER28315.1 - 6.2e-14 52.4 12.8 6.2e-14 52.4 12.8 4.7 4 0 0 4 4 4 1 Inner membrane component domain AAA PF00004.29 EER28316.1 - 7.8e-44 149.3 0.0 1.3e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER28316.1 - 4.3e-14 52.0 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EER28316.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EER28316.1 - 1.5e-07 31.7 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EER28316.1 - 2.5e-06 28.0 0.0 0.00011 22.6 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EER28316.1 - 5.1e-06 26.4 2.7 1.4e-05 25.0 2.7 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EER28316.1 - 2.6e-05 24.5 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EER28316.1 - 5.7e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EER28316.1 - 0.00028 21.4 0.1 0.019 15.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.13 EER28316.1 - 0.00097 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EER28316.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EER28316.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EER28316.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EER28316.1 - 0.0077 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EER28316.1 - 0.0085 15.5 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 KaiC TsaE PF02367.17 EER28316.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EER28316.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EER28316.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EER28316.1 - 0.023 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EER28316.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EER28316.1 - 0.032 13.7 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 EER28316.1 - 0.034 14.5 0.0 0.064 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EER28316.1 - 0.035 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EER28316.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain HR1 PF02185.16 EER28316.1 - 0.048 13.8 0.6 0.12 12.6 0.6 1.6 1 0 0 1 1 1 0 Hr1 repeat Prot_ATP_OB_N PF17758.1 EER28316.1 - 0.053 13.2 0.2 0.17 11.6 0.2 1.9 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 EER28316.1 - 0.055 13.0 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EER28316.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EER28316.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 EER28316.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein F-box-like PF12937.7 EER28317.1 - 0.1 12.5 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 F-box-like FlhC PF05280.11 EER28317.1 - 1 9.0 5.3 2.4 7.9 5.3 1.6 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) UFD1 PF03152.14 EER28318.1 - 2.6e-29 101.9 0.0 4.2e-16 58.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EER28318.1 - 4.8e-08 33.1 2.1 2.3e-06 27.7 0.1 2.8 2 0 0 2 2 2 2 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Yip1 PF04893.17 EER28319.1 - 1.7e-05 24.6 16.3 1.7e-05 24.6 16.3 2.6 2 1 0 2 2 2 1 Yip1 domain Bac_surface_Ag PF01103.23 EER28320.1 - 4.7e-47 161.1 0.0 6e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Orthopox_A5L PF06193.11 EER28320.1 - 0.16 11.3 0.6 0.32 10.4 0.5 1.4 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like UQ_con PF00179.26 EER28321.1 - 2e-20 72.9 0.2 3.1e-20 72.3 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans_2 PF11951.8 EER28322.1 - 7.1e-10 38.2 0.0 7.6e-06 25.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.17 EER28323.1 - 1.8e-124 415.1 1.9 2e-124 414.9 1.9 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Lipase_3 PF01764.25 EER28324.1 - 0.0034 17.3 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF3089 PF11288.8 EER28324.1 - 0.0043 16.6 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_6 PF12697.7 EER28324.1 - 0.0084 16.7 0.1 0.034 14.8 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.14 EER28324.1 - 0.014 14.9 0.1 0.025 14.1 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.13 EER28324.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 EER28324.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold HA2 PF04408.23 EER28325.1 - 4.1e-09 36.7 0.0 1.6e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) MADF_DNA_bdg PF10545.9 EER28325.1 - 0.081 13.3 0.6 0.28 11.5 0.5 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like AAA_29 PF13555.6 EER28325.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain OB_NTP_bind PF07717.16 EER28325.1 - 0.17 12.3 0.1 0.77 10.2 0.0 2.1 2 0 0 2 2 2 0 Oligonucleotide/oligosaccharide-binding (OB)-fold ABC1 PF03109.16 EER28326.1 - 1.9e-21 76.4 0.0 7.3e-13 48.7 0.0 2.6 3 0 0 3 3 3 2 ABC1 family RIO1 PF01163.22 EER28326.1 - 0.048 13.3 0.0 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Raf1_HTH PF18579.1 EER28326.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Rubisco accumulation factor 1 helix turn helix domain DAO PF01266.24 EER28327.1 - 3.1e-33 115.8 0.1 3.5e-33 115.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER28327.1 - 2e-06 27.9 0.0 5.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EER28327.1 - 0.00024 20.5 0.0 0.0016 17.8 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EER28327.1 - 0.00025 20.4 0.0 0.00063 19.1 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EER28327.1 - 0.00033 21.2 0.5 0.0066 17.0 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EER28327.1 - 0.00039 19.6 0.2 0.0017 17.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.6 EER28327.1 - 0.0015 19.0 0.0 0.0029 18.0 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EER28327.1 - 0.0063 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EER28327.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A SLIDE PF09111.10 EER28327.1 - 0.19 11.7 0.0 0.47 10.5 0.0 1.6 1 0 0 1 1 1 0 SLIDE MFS_1 PF07690.16 EER28328.1 - 1.2e-43 149.4 39.5 1.2e-43 149.4 39.5 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER28328.1 - 8.5e-16 57.8 27.3 1.3e-13 50.7 4.6 3.9 4 0 0 4 4 4 2 Sugar (and other) transporter Pro_CA PF00484.19 EER28329.1 - 8.7e-14 52.1 0.3 8.3e-13 48.9 0.3 2.0 1 1 0 1 1 1 1 Carbonic anhydrase SLAC1 PF03595.17 EER28330.1 - 6.3e-77 259.0 57.1 7.3e-77 258.8 57.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel adh_short PF00106.25 EER28331.1 - 3.3e-40 137.6 0.0 4.3e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER28331.1 - 6.2e-26 91.4 0.0 7.9e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EER28331.1 - 0.00011 21.7 0.0 0.0045 16.4 0.0 2.1 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EER28331.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family ATP-grasp_2 PF08442.10 EER28332.1 - 1.3e-77 259.9 0.8 2.5e-77 259.0 0.8 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EER28332.1 - 4.4e-25 88.3 0.2 8.2e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EER28332.1 - 3.7e-10 39.6 0.5 7.7e-10 38.6 0.2 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EER28332.1 - 0.0023 17.7 0.4 0.057 13.2 0.0 2.4 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain VID27_N PF17748.1 EER28332.1 - 0.044 13.6 0.4 0.085 12.7 0.4 1.4 1 0 0 1 1 1 0 VID27 N-terminal region CPSase_L_D2 PF02786.17 EER28332.1 - 0.057 12.9 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF3245 PF11595.8 EER28333.1 - 1.8e-38 132.3 7.5 3.7e-38 131.3 7.5 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) HSF_DNA-bind PF00447.17 EER28334.1 - 6.3e-30 103.7 0.6 1e-29 103.0 0.6 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF4439 PF14530.6 EER28334.1 - 0.046 14.4 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4439) F-box-like PF12937.7 EER28335.1 - 1.2e-05 25.1 0.0 3.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER28335.1 - 0.0001 22.1 2.2 0.00012 21.9 0.0 2.4 2 0 0 2 2 2 1 F-box domain Phage_int_SAM_4 PF13495.6 EER28337.1 - 0.08 13.4 0.2 0.17 12.4 0.2 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Radical_SAM PF04055.21 EER28338.1 - 0.00024 21.5 0.0 0.00078 19.9 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Pkinase PF00069.25 EER28340.1 - 2.1e-06 27.3 0.0 2.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pribosyltran PF00156.27 EER28341.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.11 EER28342.1 - 1.3e-31 108.6 0.6 1.4e-31 108.5 0.6 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF5079 PF16882.5 EER28342.1 - 0.011 15.6 0.1 0.013 15.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5079) Abhydrolase_6 PF12697.7 EER28343.1 - 3.3e-15 57.3 0.0 1e-14 55.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER28343.1 - 1.3e-13 51.2 0.0 3.4e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER28343.1 - 1.3e-09 37.7 0.0 3.1e-09 36.5 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EER28343.1 - 0.0064 16.6 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 EER28343.1 - 0.053 13.4 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold SCP2 PF02036.17 EER28343.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 SCP-2 sterol transfer family Zn_clus PF00172.18 EER28344.1 - 2.1e-06 27.8 9.1 4e-06 26.8 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FSH1 PF03959.13 EER28345.1 - 1.2e-25 90.4 0.0 2.4e-16 60.0 0.0 2.8 2 1 0 2 2 2 2 Serine hydrolase (FSH1) Methyltransf_2 PF00891.18 EER28346.1 - 2.2e-18 66.3 0.0 3.5e-18 65.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain PaO PF08417.12 EER28346.1 - 0.13 12.4 0.1 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Pheophorbide a oxygenase AflR PF08493.10 EER28347.1 - 3.6e-10 39.8 0.6 3.6e-10 39.8 0.6 1.9 2 1 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.18 EER28347.1 - 1.2e-06 28.5 8.6 2.4e-06 27.6 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EER28348.1 - 1.8e-39 135.7 49.7 6.9e-39 133.8 49.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2909 PF11137.8 EER28348.1 - 0.71 9.9 8.7 6.5 6.8 0.1 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2909) FAS_I_H PF18314.1 EER28349.1 - 7.7e-58 195.5 0.0 1.5e-57 194.5 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EER28349.1 - 2.5e-48 164.5 0.0 6.3e-48 163.2 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EER28349.1 - 7.6e-23 81.4 0.0 1.9e-22 80.1 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EER28349.1 - 2.7e-16 59.6 0.0 1.7e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.20 EER28349.1 - 3.8e-15 56.0 0.0 9.5e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.25 EER28349.1 - 2.4e-05 23.9 0.0 8.2e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase DUF1729 PF08354.10 EER28350.1 - 1.8e-146 487.6 0.0 2.7e-146 487.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EER28350.1 - 6.3e-68 229.6 2.4 6.3e-67 226.3 0.0 2.6 3 0 0 3 3 3 1 Acyl transferase domain SAT PF16073.5 EER28350.1 - 3.9e-28 98.8 0.3 1.2e-27 97.3 0.0 1.9 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EER28350.1 - 7.6e-25 86.9 0.0 2.2e-24 85.4 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain FAS_meander PF17951.1 EER28350.1 - 6.4e-10 39.0 0.0 1.9e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydrat_N PF13452.6 EER28350.1 - 6.9e-10 39.2 0.0 4.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ketoacyl-synt PF00109.26 EER28351.1 - 7.6e-83 278.0 0.0 1.7e-82 276.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EER28351.1 - 4.1e-60 203.5 4.2 1.1e-59 202.1 1.3 2.7 2 1 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EER28351.1 - 1.2e-42 146.5 0.4 2.7e-42 145.4 0.1 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EER28351.1 - 2.7e-35 120.9 0.1 5.8e-35 119.9 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 EER28351.1 - 3.2e-33 115.8 0.0 2.8e-32 112.7 0.0 2.3 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.25 EER28351.1 - 5.7e-21 74.6 3.5 1.3e-10 41.5 0.3 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 EER28351.1 - 7.1e-13 48.4 0.0 1.1e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EER28351.1 - 7.3e-06 26.4 0.0 1.8e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EER28351.1 - 0.0011 18.4 0.1 0.0022 17.4 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_1 PF00561.20 EER28351.1 - 0.0019 17.9 0.0 0.22 11.1 0.0 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_M35 PF02102.15 EER28352.1 - 1.3e-104 350.0 0.0 1.5e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EER28352.1 - 2.3e-39 135.2 0.6 2.3e-39 135.2 0.6 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase KAP PF05804.12 EER28353.1 - 2.5e-07 29.3 0.1 3.3e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Mac PF12464.8 EER28353.1 - 0.08 13.2 0.2 1.1 9.6 0.1 2.4 2 0 0 2 2 2 0 Maltose acetyltransferase MetOD2 PF18548.1 EER28353.1 - 0.2 11.8 0.3 0.49 10.5 0.3 1.6 1 0 0 1 1 1 0 Metanogen output domain 2 Arm PF00514.23 EER28353.1 - 0.24 11.5 7.5 4.4 7.5 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Oxidored-like PF09791.9 EER28354.1 - 4.8e-24 83.8 4.1 4.8e-24 83.8 4.1 2.2 3 0 0 3 3 3 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 EER28354.1 - 0.058 13.4 3.1 0.15 12.0 3.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Ribosomal_L13e PF01294.18 EER28356.1 - 2.8e-77 258.6 2.8 4.3e-77 258.0 2.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e CENP-F_leu_zip PF10473.9 EER28357.1 - 0.032 14.2 4.9 0.057 13.4 4.9 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Borrelia_orfA PF02414.15 EER28357.1 - 0.2 11.3 0.1 0.29 10.8 0.1 1.2 1 0 0 1 1 1 0 Borrelia ORF-A LRR_4 PF12799.7 EER28358.1 - 4.3e-28 96.9 37.5 1.2e-06 28.7 1.0 9.6 6 2 5 11 11 11 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EER28358.1 - 6.4e-28 96.3 44.6 7.8e-09 35.2 3.0 8.4 6 2 1 8 8 8 7 Leucine rich repeat LRR_9 PF14580.6 EER28358.1 - 5.3e-07 29.3 12.3 0.0047 16.4 0.5 4.5 3 1 1 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 EER28358.1 - 7e-07 28.9 42.1 2.6 8.9 0.1 13.6 15 0 0 15 15 15 2 Leucine Rich Repeat RsmF_methylt_CI PF17126.5 EER28358.1 - 0.0052 16.8 0.0 4.1 7.5 0.0 3.9 4 0 0 4 4 4 1 RsmF rRNA methyltransferase first C-terminal domain LRR_6 PF13516.6 EER28358.1 - 0.053 13.6 37.6 0.86 9.8 0.3 10.8 12 0 0 12 12 12 0 Leucine Rich repeat GCIP PF13324.6 EER28359.1 - 2.5e-25 89.6 1.0 4.1e-25 88.9 1.0 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting PPIP5K2_N PF18086.1 EER28359.1 - 0.033 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain Actin PF00022.19 EER28360.1 - 7.1e-100 334.5 0.0 8.3e-99 330.9 0.0 1.9 1 1 0 1 1 1 1 Actin IBR PF01485.21 EER28361.1 - 1.1e-08 35.1 34.6 0.00014 22.0 5.3 3.5 3 0 0 3 3 3 3 IBR domain, a half RING-finger domain 3HCDH_N PF02737.18 EER28362.1 - 1.3e-53 181.5 2.3 1.8e-53 181.1 2.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EER28362.1 - 5.1e-35 120.0 0.0 1.2e-34 118.8 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.16 EER28362.1 - 3.1e-06 26.9 0.2 7.9e-05 22.3 0.2 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EER28362.1 - 1.7e-05 25.0 0.6 4.6e-05 23.6 0.6 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_2 PF07992.14 EER28362.1 - 0.00048 19.5 0.1 0.00066 19.0 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EER28362.1 - 0.00066 19.3 1.7 0.0048 16.5 1.6 2.1 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.24 EER28362.1 - 0.00067 19.3 0.4 0.0011 18.6 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 EER28362.1 - 0.0011 18.9 0.2 0.0018 18.3 0.2 1.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EER28362.1 - 0.0012 19.1 0.3 0.0022 18.3 0.3 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 EER28362.1 - 0.012 16.2 0.5 0.024 15.2 0.2 1.7 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER28362.1 - 0.053 12.2 0.7 0.09 11.5 0.7 1.3 1 0 0 1 1 1 0 HI0933-like protein DAHP_synth_1 PF00793.20 EER28362.1 - 0.06 12.2 0.2 1.2 8.0 0.1 2.2 2 0 0 2 2 2 0 DAHP synthetase I family PALP PF00291.25 EER28362.1 - 0.062 12.7 0.3 0.098 12.1 0.3 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 EER28362.1 - 0.097 12.9 0.1 0.22 11.8 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EER28362.1 - 0.12 11.7 0.4 0.3 10.4 0.2 1.8 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EER28362.1 - 0.14 11.2 0.3 0.22 10.5 0.3 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein F420_oxidored PF03807.17 EER28362.1 - 0.62 10.7 3.9 1.1 9.9 1.9 2.4 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TIMELESS PF04821.14 EER28363.1 - 2e-84 283.2 0.0 5.1e-84 281.8 0.0 1.8 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 EER28363.1 - 1.2e-44 153.4 7.5 3.5e-43 148.6 3.2 3.3 1 1 1 2 2 2 1 Timeless protein C terminal region DUF4866 PF16160.5 EER28363.1 - 0.045 13.1 0.2 3.8 6.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4866) Trm5_N PF18093.1 EER28363.1 - 0.17 11.8 0.2 0.41 10.6 0.2 1.6 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain DUF4778 PF16008.5 EER28363.1 - 3.8 7.5 16.0 7 6.6 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4778) PhzC-PhzF PF02567.16 EER28364.1 - 4.2e-44 151.1 0.0 1.3e-43 149.5 0.0 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein DUF4878 PF12870.7 EER28364.1 - 0.18 12.2 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) Tfb2 PF03849.14 EER28366.1 - 5.3e-139 463.1 0.0 9.8e-139 462.2 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EER28366.1 - 1.7e-24 86.0 0.2 3.3e-24 85.1 0.2 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EER28366.1 - 7.6e-07 29.3 0.1 9.4e-05 22.6 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain 4HBT PF03061.22 EER28367.1 - 4.7e-14 52.5 0.0 7.9e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EER28367.1 - 0.031 14.5 0.0 0.035 14.4 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.6 EER28367.1 - 0.087 13.0 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Aquarius_N PF16399.5 EER28368.1 - 0 1068.5 0.2 0 1068.2 0.2 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EER28368.1 - 8.1e-27 94.1 0.0 1.5e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EER28368.1 - 3.5e-22 79.5 0.0 8.1e-22 78.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EER28368.1 - 1.8e-06 27.8 0.0 0.00061 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EER28368.1 - 3.3e-06 27.5 0.0 7.7e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EER28368.1 - 1.5e-05 25.0 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EER28368.1 - 0.0014 19.0 0.0 0.0051 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 EER28368.1 - 0.002 17.5 0.0 0.0037 16.6 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 EER28368.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EER28368.1 - 0.0066 16.2 0.1 0.36 10.5 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EER28368.1 - 0.011 15.0 0.6 0.027 13.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EER28368.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EER28368.1 - 0.032 14.2 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 EER28368.1 - 0.05 13.4 0.1 0.12 12.2 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EER28368.1 - 0.05 13.1 0.0 0.16 11.4 0.0 1.9 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain DEAD PF00270.29 EER28368.1 - 0.075 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase PIF1 PF05970.14 EER28368.1 - 0.076 12.2 0.0 12 5.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_22 PF13401.6 EER28368.1 - 0.093 13.0 0.0 0.34 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain efThoc1 PF11957.8 EER28369.1 - 1.4e-149 498.9 2.1 1.8e-149 498.6 2.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor HCMVantigenic_N PF12154.8 EER28369.1 - 0.052 13.7 1.3 0.1 12.7 1.3 1.5 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Homeodomain PF00046.29 EER28370.1 - 7.4e-17 60.9 2.9 1.4e-16 60.0 2.9 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EER28370.1 - 0.051 13.5 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Homeobox KN domain Adaptin_N PF01602.20 EER28372.1 - 3.4e-127 425.2 5.0 4.4e-127 424.8 5.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EER28372.1 - 1.6e-42 144.2 0.0 4.9e-42 142.7 0.0 1.9 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EER28372.1 - 1.8e-18 66.9 0.0 4.6e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Proteasom_PSMB PF10508.9 EER28372.1 - 0.038 12.5 1.7 0.096 11.2 1.1 1.9 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Flavi_glycoprot PF00869.20 EER28372.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains Ala_racemase_N PF01168.20 EER28373.1 - 1.6e-23 83.5 0.0 2.4e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Fungal_trans PF04082.18 EER28375.1 - 5.1e-24 84.7 0.0 1.5e-23 83.2 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28375.1 - 2.5e-09 37.1 9.1 4.6e-09 36.3 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspA_IM30 PF04012.12 EER28375.1 - 0.0066 16.1 2.5 0.016 14.8 2.5 1.5 1 0 0 1 1 1 1 PspA/IM30 family TGT PF01702.18 EER28376.1 - 1.6e-144 481.4 0.0 1.9e-144 481.2 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.19 EER28377.1 - 1.3e-104 349.1 0.0 1.5e-104 348.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase zf-AN1 PF01428.16 EER28378.1 - 2.2e-23 82.1 32.2 3.1e-12 46.4 11.5 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.21 EER28378.1 - 0.016 15.4 5.5 0.016 15.4 5.5 2.8 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Transp_Tc5_C PF04236.15 EER28378.1 - 0.1 13.0 15.1 0.18 12.1 5.4 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain C1_4 PF07975.12 EER28378.1 - 1.2 9.4 18.5 3.8 7.8 8.2 2.9 2 2 0 2 2 2 0 TFIIH C1-like domain DUF5090 PF17009.5 EER28379.1 - 0.044 13.7 0.6 0.044 13.7 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Hist_deacetyl PF00850.19 EER28380.1 - 7.5e-51 173.4 0.0 1.2e-50 172.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Peptidase_M28 PF04389.17 EER28381.1 - 1.2e-30 106.7 0.4 1.6e-30 106.3 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EER28381.1 - 2.2e-05 24.3 0.3 7e-05 22.6 0.3 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 bPH_6 PF10756.9 EER28381.1 - 0.13 12.4 0.1 0.35 11.0 0.1 1.8 1 0 0 1 1 1 0 Bacterial PH domain DUF1774 PF08611.10 EER28382.1 - 3.9e-32 110.4 0.6 3.9e-32 110.4 0.6 2.1 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF2723 PF11028.8 EER28382.1 - 0.0002 21.3 5.0 0.00056 19.9 5.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2723) Sigma_reg_N PF13800.6 EER28382.1 - 3.4 8.0 6.9 0.8 10.0 0.6 2.7 2 1 1 3 3 3 0 Sigma factor regulator N-terminal Protoglobin PF11563.8 EER28383.1 - 1.3e-57 194.1 0.0 1.6e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Protoglobin Tsi6 PF18660.1 EER28383.1 - 0.011 15.8 0.0 0.4 10.8 0.1 2.3 2 0 0 2 2 2 0 Tsi6 dCMP_cyt_deam_1 PF00383.23 EER28384.1 - 3.7e-06 26.7 0.1 4.4e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MtmB PF05369.12 EER28384.1 - 0.012 14.5 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Chitin_synth_1 PF01644.17 EER28385.1 - 1.5e-78 262.4 0.1 2.2e-78 261.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EER28385.1 - 1.2e-27 95.7 0.1 2.8e-27 94.5 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EER28385.1 - 2e-22 79.6 3.4 3.3e-21 75.5 0.1 2.3 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EER28385.1 - 1.2e-06 28.6 0.8 1.2e-06 28.6 0.8 2.6 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Ninjurin PF04923.12 EER28385.1 - 0.065 13.2 0.6 0.17 11.8 0.6 1.6 1 0 0 1 1 1 0 Ninjurin AFG1_ATPase PF03969.16 EER28386.1 - 1.2e-92 310.6 0.0 4.1e-88 295.7 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EER28386.1 - 0.00045 20.7 0.1 0.32 11.4 0.0 2.7 3 0 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 EER28386.1 - 0.0014 18.6 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EER28386.1 - 0.0039 17.6 0.0 0.0096 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EER28386.1 - 0.014 15.4 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EER28386.1 - 0.023 14.9 0.0 0.079 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 EER28386.1 - 0.088 12.6 0.1 2.6 7.9 0.1 2.3 2 1 0 2 2 2 0 Bacterial dnaA protein RNA_helicase PF00910.22 EER28386.1 - 0.12 12.7 0.0 0.44 11.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase SH3_1 PF00018.28 EER28387.1 - 3.5e-25 87.3 0.0 3e-11 42.7 0.0 3.3 4 0 0 4 4 4 2 SH3 domain SH3_9 PF14604.6 EER28387.1 - 2.3e-14 52.9 2.0 1.6e-06 27.9 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.24 EER28387.1 - 5.4e-13 48.9 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EER28387.1 - 4.5e-10 39.0 0.0 3.3e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 EER28387.1 - 1.1e-08 34.8 0.8 2.3e-08 33.9 0.8 1.5 1 0 0 1 1 1 1 PB1 domain DUF5576 PF17739.1 EER28387.1 - 0.37 10.9 2.4 0.38 10.9 0.6 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5576) SAC3_GANP PF03399.16 EER28388.1 - 3.3e-25 89.1 2.8 3.8e-23 82.3 2.8 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EER28388.1 - 0.00032 20.7 0.1 0.00073 19.5 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family EAP30 PF04157.16 EER28389.1 - 1.6e-42 145.5 0.0 2e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EER28389.1 - 2.1e-24 85.5 0.0 3.4e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 EER28389.1 - 6.9e-23 79.8 1.8 6.9e-23 79.8 1.8 2.6 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 EER28389.1 - 0.00029 20.1 13.8 0.00064 19.0 1.1 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.15 EER28389.1 - 0.00046 20.2 4.1 0.0073 16.3 0.3 2.5 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger GRAM PF02893.20 EER28389.1 - 0.0038 17.1 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DZR PF12773.7 EER28389.1 - 0.027 14.5 4.6 0.047 13.7 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon RecR PF02132.15 EER28389.1 - 1.2 8.8 3.0 3.9 7.1 0.5 2.6 2 0 0 2 2 2 0 RecR protein FKBP_C PF00254.28 EER28392.1 - 4.5e-22 78.2 0.0 5.3e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_N_2 PF18023.1 EER28392.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.8 1 1 0 1 1 1 0 BDBT FKBP like N-terminal APH PF01636.23 EER28393.1 - 0.0051 16.8 0.2 0.0051 16.8 0.2 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Alanine_zipper PF11839.8 EER28393.1 - 0.0098 16.2 5.7 0.0098 16.2 5.7 2.0 2 0 0 2 2 2 1 Alanine-zipper, major outer membrane lipoprotein CENP-F_leu_zip PF10473.9 EER28393.1 - 0.015 15.4 4.4 0.043 13.8 4.4 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Kdo PF06293.14 EER28393.1 - 0.04 13.3 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Brr6_like_C_C PF10104.9 EER28393.1 - 0.49 10.2 1.5 1 9.1 1.5 1.4 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Med9 PF07544.13 EER28393.1 - 2.7 8.1 5.6 6.7 6.9 5.6 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_M43 PF05572.13 EER28394.1 - 1.4e-15 57.5 0.0 2.8e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EER28394.1 - 3.7e-05 24.0 0.1 5.3e-05 23.5 0.1 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EER28394.1 - 4e-05 24.1 0.0 9.6e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EER28394.1 - 0.0048 16.7 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 EER28394.1 - 0.0061 16.2 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 EER28394.1 - 0.023 14.8 0.3 0.047 13.8 0.3 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Peptidase_M66 PF10462.9 EER28394.1 - 0.028 13.4 0.4 0.043 12.7 0.4 1.2 1 0 0 1 1 1 0 Peptidase M66 AsiA PF09010.10 EER28395.1 - 0.14 12.3 0.0 6.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Anti-Sigma Factor A PHP PF02811.19 EER28396.1 - 8.5e-14 52.2 0.0 2.9e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 PHP domain ACPS PF01648.20 EER28397.1 - 6.5e-15 55.3 0.0 8.1e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EER28397.1 - 0.0044 17.1 0.4 1.3 9.2 0.1 2.3 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain AAT PF03417.16 EER28398.1 - 1.9e-25 89.9 0.0 2.4e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ATP19 PF11022.8 EER28399.1 - 4.6e-25 87.8 0.1 5.5e-25 87.5 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MTP18 PF10558.9 EER28400.1 - 5.5e-80 267.3 0.0 1.1e-79 266.4 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) MFS_1 PF07690.16 EER28402.1 - 5.8e-33 114.3 32.8 5.8e-33 114.3 32.8 2.1 3 0 0 3 3 3 1 Major Facilitator Superfamily DUF4579 PF15158.6 EER28402.1 - 2.4 7.9 4.8 1.6 8.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) Cys_Met_Meta_PP PF01053.20 EER28403.1 - 5.5e-142 472.8 0.0 6.4e-142 472.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EER28403.1 - 0.00066 19.1 0.0 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EER28403.1 - 0.00086 17.9 0.0 0.01 14.4 0.0 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EER28403.1 - 0.051 12.9 0.0 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 Beta-eliminating lyase ZFYVE21_C PF16696.5 EER28403.1 - 0.15 12.0 0.0 2.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Zinc finger FYVE domain-containing protein 21 C-terminus AAA PF00004.29 EER28404.1 - 5e-37 127.3 0.0 1.1e-36 126.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER28404.1 - 2.6e-08 33.5 0.1 6.3e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EER28404.1 - 9.4e-06 25.7 0.2 0.00019 21.4 0.2 2.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EER28404.1 - 2.2e-05 24.3 0.0 5.4e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EER28404.1 - 2.7e-05 24.6 0.9 0.00015 22.2 0.1 2.7 2 1 0 2 2 1 1 AAA ATPase domain AAA_14 PF13173.6 EER28404.1 - 4.2e-05 23.6 0.0 8.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EER28404.1 - 0.00024 21.2 0.0 0.00051 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EER28404.1 - 0.00047 20.5 0.9 0.0055 17.0 0.0 2.8 3 1 1 4 4 2 1 AAA domain AAA_33 PF13671.6 EER28404.1 - 0.00055 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EER28404.1 - 0.00056 20.5 0.1 0.003 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EER28404.1 - 0.00097 18.9 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EER28404.1 - 0.0011 18.4 0.1 0.0021 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EER28404.1 - 0.0015 18.9 0.0 0.0053 17.1 0.0 2.0 1 1 1 2 2 2 1 RNA helicase AAA_25 PF13481.6 EER28404.1 - 0.0015 18.1 0.1 0.033 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EER28404.1 - 0.0035 16.8 0.0 3 7.2 0.0 2.5 1 1 0 2 2 2 2 Bacterial TniB protein NACHT PF05729.12 EER28404.1 - 0.005 16.8 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 EER28404.1 - 0.0082 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EER28404.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EER28404.1 - 0.015 15.2 0.1 0.052 13.5 0.0 1.9 1 1 1 2 2 2 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 EER28404.1 - 0.017 15.2 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EER28404.1 - 0.018 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EER28404.1 - 0.023 14.4 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EER28404.1 - 0.029 14.9 0.0 0.08 13.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 EER28404.1 - 0.061 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 EER28404.1 - 0.072 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EER28404.1 - 0.077 12.9 0.0 0.24 11.3 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EER28404.1 - 0.085 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EER28404.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EER28404.1 - 0.12 12.2 0.2 0.87 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EER28404.1 - 0.12 11.5 0.1 0.37 9.9 0.0 1.8 2 0 0 2 2 2 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 EER28404.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EER28404.1 - 0.18 11.0 0.3 0.58 9.3 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.22 EER28404.1 - 0.23 11.6 2.0 0.61 10.2 0.0 2.4 3 0 0 3 3 2 0 Shikimate kinase Csm1 PF12539.8 EER28405.1 - 2.5e-30 105.0 0.2 6.7e-30 103.6 0.2 1.8 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Spc42p PF11544.8 EER28405.1 - 0.00044 20.2 1.2 0.003 17.5 0.1 2.5 2 0 0 2 2 2 1 Spindle pole body component Spc42p End3 PF12761.7 EER28405.1 - 0.00052 20.3 5.5 0.00052 20.3 5.5 1.9 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 KxDL PF10241.9 EER28405.1 - 0.00079 19.7 9.4 0.0092 16.2 2.3 2.5 1 1 1 2 2 2 1 Uncharacterized conserved protein AAA_13 PF13166.6 EER28405.1 - 0.0014 17.4 2.2 0.0014 17.4 2.2 1.9 2 0 0 2 2 2 1 AAA domain UPF0242 PF06785.11 EER28405.1 - 0.0045 17.1 4.1 0.0045 17.1 4.1 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus PKcGMP_CC PF16808.5 EER28405.1 - 0.014 15.3 1.6 0.025 14.4 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase EzrA PF06160.12 EER28405.1 - 0.026 12.7 4.9 0.061 11.5 4.9 1.5 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Flagellin_C PF00700.21 EER28405.1 - 0.032 14.6 4.7 2.1 8.8 0.5 2.6 1 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF4201 PF13870.6 EER28405.1 - 0.039 13.7 9.9 0.14 11.9 3.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) LPP PF04728.13 EER28405.1 - 0.06 13.8 0.9 0.06 13.8 0.9 4.0 5 0 0 5 5 2 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 EER28405.1 - 0.078 13.0 6.1 0.17 11.9 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 EER28405.1 - 0.11 13.1 6.2 0.44 11.1 5.9 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FapA PF03961.13 EER28405.1 - 0.13 10.8 4.8 0.23 10.0 4.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4988 PF16378.5 EER28405.1 - 0.17 11.5 0.7 0.52 10.0 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function SOCS_box PF07525.16 EER28405.1 - 0.21 12.0 0.5 0.42 11.0 0.5 1.4 1 0 0 1 1 1 0 SOCS box DUF16 PF01519.16 EER28405.1 - 0.67 10.5 3.5 2.1 8.9 0.8 2.5 1 1 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 EER28405.1 - 0.77 9.8 3.5 0.43 10.6 1.1 1.8 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Matrilin_ccoil PF10393.9 EER28405.1 - 0.78 9.6 7.7 0.83 9.6 0.3 3.2 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Fib_alpha PF08702.10 EER28405.1 - 0.99 9.6 5.3 2.4 8.4 5.3 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HrpB7 PF09486.10 EER28405.1 - 1.1 9.6 19.9 0.034 14.6 9.3 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) GAS PF13851.6 EER28405.1 - 1.3 8.3 18.1 0.068 12.5 10.9 2.3 2 1 0 2 2 1 0 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 EER28405.1 - 1.3 9.4 8.4 1.1 9.6 1.9 3.8 1 1 3 4 4 4 0 Csm1 N-terminal domain Spc7 PF08317.11 EER28405.1 - 1.7 7.4 18.0 0.063 12.2 11.5 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein COG5 PF10392.9 EER28405.1 - 2.8 8.1 7.5 13 5.9 0.3 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Atg14 PF10186.9 EER28405.1 - 4 6.4 16.1 0.065 12.3 8.7 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EER28405.1 - 4.3 6.8 12.5 0.17 11.5 6.3 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 EER28405.1 - 4.8 6.5 13.7 0.2 11.1 7.3 1.9 2 0 0 2 2 2 0 Golgin subfamily A member 5 V_ATPase_I PF01496.19 EER28405.1 - 6.5 4.5 11.8 0.028 12.4 1.9 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family COG2 PF06148.11 EER28405.1 - 8.6 6.5 7.1 24 5.0 1.6 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PigN PF04987.14 EER28406.1 - 6.8e-166 552.6 40.4 9.9e-166 552.1 40.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EER28406.1 - 8.2e-10 38.8 2.4 2.8e-08 33.8 2.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EER28406.1 - 1.6e-09 37.6 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EER28406.1 - 0.00068 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.18 EER28407.1 - 9.1e-35 120.0 0.0 2.1e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28407.1 - 9.9e-08 32.0 8.4 1.7e-07 31.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.20 EER28408.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 LysM domain PRK PF00485.18 EER28409.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RVT_2 PF07727.14 EER28410.1 - 6.3e-51 173.4 0.0 9.6e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EER28410.1 - 1.7e-14 54.0 0.0 8.9e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EER28410.1 - 4.2e-06 26.5 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 EER28410.1 - 0.001 19.0 1.7 0.0022 18.0 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 EER28410.1 - 0.01 15.5 0.0 0.01 15.5 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type rve_3 PF13683.6 EER28410.1 - 0.081 12.7 0.1 2.8 7.8 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain Neugrin PF06413.11 EER28410.1 - 0.15 12.0 6.5 0.34 10.9 5.2 2.3 2 0 0 2 2 2 0 Neugrin adh_short PF00106.25 EER28411.1 - 1.9e-84 282.0 6.9 1.4e-45 155.2 0.8 2.6 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EER28411.1 - 1.3e-66 224.6 4.3 1.2e-35 123.2 0.7 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EER28411.1 - 7.9e-33 112.7 0.0 1.5e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EER28411.1 - 1.3e-25 90.4 1.8 3.2e-12 46.7 0.2 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EER28411.1 - 0.00017 20.9 0.4 0.033 13.5 0.2 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PglL_A PF15864.5 EER28411.1 - 1.2 9.0 6.6 5.5 6.8 1.0 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase IBR PF01485.21 EER28412.1 - 3e-05 24.2 2.5 3e-05 24.2 2.5 5.0 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain DUF826 PF05696.11 EER28412.1 - 0.043 13.9 0.0 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Yip1 PF04893.17 EER28413.1 - 3.2e-14 53.0 16.3 6.1e-14 52.1 16.3 1.5 1 1 0 1 1 1 1 Yip1 domain 7TM_transglut PF14402.6 EER28413.1 - 0.9 8.9 9.2 1.2 8.5 9.2 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Ran_BP1 PF00638.18 EER28414.1 - 2.6e-16 60.0 0.0 5.2e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain FSA_C PF10479.9 EER28414.1 - 1.9 6.5 5.3 0.73 7.9 2.7 1.5 1 1 1 2 2 2 0 Fragile site-associated protein C-terminus DEAD PF00270.29 EER28415.1 - 1.4e-28 99.8 0.0 2.4e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EER28415.1 - 4.5e-21 75.4 0.0 1.1e-20 74.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EER28415.1 - 4.5e-12 46.3 0.1 1.7e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER28415.1 - 7.8e-06 26.0 0.0 1.6e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EER28415.1 - 6.7e-05 23.2 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like DUF244 PF03112.14 EER28415.1 - 0.015 15.1 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Fungal_trans_2 PF11951.8 EER28416.1 - 1.2e-10 40.7 1.1 2.2e-10 39.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28416.1 - 1.5e-05 25.0 9.5 3.2e-05 24.0 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 EER28417.1 - 3.4e-08 33.0 2.0 0.005 16.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EER28417.1 - 3.4e-07 29.8 1.1 0.031 14.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EER28417.1 - 0.00026 21.2 0.9 0.074 13.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EER28417.1 - 0.00032 21.2 0.2 0.031 14.8 0.0 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EER28417.1 - 0.0013 18.6 0.6 1.9 8.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER28417.1 - 0.0015 18.2 0.5 0.21 11.3 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_16 PF13432.6 EER28417.1 - 0.002 18.7 0.8 2.6 8.8 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EER28417.1 - 0.0025 18.0 0.0 0.0097 16.1 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EER28417.1 - 0.0063 16.6 0.4 0.38 10.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EER28417.1 - 0.077 13.2 0.2 1.1 9.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zinc_ribbon_6 PF14599.6 EER28417.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon TPR_10 PF13374.6 EER28417.1 - 0.15 12.0 0.2 11 6.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EER28417.1 - 0.28 12.1 2.1 1.7 9.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ceramidase PF05875.12 EER28418.1 - 5.1e-35 121.2 4.9 5.9e-35 121.0 4.9 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 EER28418.1 - 1.1 9.4 9.1 0.25 11.4 4.6 2.3 2 0 0 2 2 2 0 Trp-operon Leader Peptide zf-RING_2 PF13639.6 EER28419.1 - 9e-13 48.3 4.7 1.4e-12 47.7 4.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EER28419.1 - 6.1e-10 39.2 3.0 1.1e-09 38.4 3.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EER28419.1 - 1.4e-07 31.1 1.9 2.7e-07 30.2 1.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EER28419.1 - 4.9e-07 29.5 2.9 7.7e-07 28.8 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER28419.1 - 1.2e-06 28.2 4.2 1.9e-06 27.6 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER28419.1 - 3.2e-06 27.0 2.6 4.9e-06 26.4 2.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EER28419.1 - 1e-05 25.1 1.6 1.9e-05 24.2 1.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EER28419.1 - 2.6e-05 24.0 2.1 4.4e-05 23.2 2.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EER28419.1 - 5.7e-05 22.9 2.6 9.1e-05 22.2 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EER28419.1 - 8.7e-05 22.5 1.5 0.00025 21.0 1.5 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EER28419.1 - 0.0016 18.4 2.9 0.0032 17.4 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.7 EER28419.1 - 0.0074 16.4 5.6 0.012 15.7 5.6 1.4 1 0 0 1 1 1 1 RING-variant domain zf-C3H2C3 PF17122.5 EER28419.1 - 0.0091 16.0 1.4 0.019 15.0 1.4 1.5 1 0 0 1 1 1 1 Zinc-finger FANCL_C PF11793.8 EER28419.1 - 0.027 14.6 3.3 0.05 13.8 3.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EER28419.1 - 0.041 13.7 1.4 0.08 12.8 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 EER28419.1 - 0.069 13.0 1.4 0.12 12.3 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EER28419.1 - 0.33 10.9 3.0 0.33 10.9 1.4 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 EER28419.1 - 0.49 10.3 2.7 0.83 9.6 2.7 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 EER28419.1 - 0.54 10.6 2.0 1 9.7 2.0 1.4 1 0 0 1 1 1 0 RING-like domain ECM11 PF15463.6 EER28420.1 - 6e-43 146.6 7.5 2.4e-42 144.7 0.0 3.1 3 0 0 3 3 3 2 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.12 EER28420.1 - 1.3e-07 31.4 0.0 0.00012 21.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor TPR_6 PF13174.6 EER28420.1 - 0.19 12.5 0.9 11 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat bZIP_1 PF00170.21 EER28421.1 - 4.3e-05 23.5 11.3 4.3e-05 23.5 11.3 3.6 2 1 2 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 EER28421.1 - 7.7e-05 22.7 11.8 7.7e-05 22.7 11.8 3.4 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 EER28421.1 - 0.00017 22.0 15.3 0.00017 22.0 15.3 3.6 2 2 2 4 4 4 1 bZIP Maf transcription factor Acyltransf_C PF16076.5 EER28421.1 - 0.16 12.1 0.1 0.51 10.5 0.1 1.8 1 0 0 1 1 1 0 Acyltransferase C-terminus V_ATPase_I PF01496.19 EER28421.1 - 4.5 5.1 7.2 6.8 4.5 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-CCCH PF00642.24 EER28422.1 - 2.2e-15 56.1 23.1 2.3e-05 24.2 1.4 5.4 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EER28422.1 - 1.8e-09 37.3 32.3 0.027 14.5 2.2 6.2 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 EER28422.1 - 1.1e-06 28.3 1.9 0.00098 18.9 0.9 5.4 5 1 0 5 5 5 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EER28422.1 - 0.00023 21.3 12.8 0.0059 16.8 0.6 3.7 2 2 1 3 3 3 2 Zinc-finger containing family Torus PF16131.5 EER28422.1 - 0.0025 18.5 24.3 0.032 14.9 1.8 4.6 2 1 3 5 5 5 2 Torus domain zf-CCCH_2 PF14608.6 EER28422.1 - 0.042 14.3 1.4 0.042 14.3 1.4 5.8 6 0 0 6 6 6 0 RNA-binding, Nab2-type zinc finger CENP-B_dimeris PF09026.10 EER28422.1 - 0.11 12.9 4.5 0.2 12.0 4.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SpoU_methylas_C PF12105.8 EER28422.1 - 0.14 11.8 0.1 0.31 10.8 0.1 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Ebp2 PF05890.12 EER28422.1 - 0.23 11.0 4.6 0.38 10.3 4.6 1.2 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 zf-C3H1 PF10650.9 EER28422.1 - 0.48 10.2 0.0 0.48 10.2 0.0 4.6 5 0 0 5 5 5 0 Putative zinc-finger domain TFIIF_beta_N PF17683.1 EER28423.1 - 3.5e-32 111.9 0.5 6.4e-32 111.1 0.5 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EER28423.1 - 1e-28 99.2 0.5 1.8e-28 98.4 0.5 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EER28423.1 - 0.03 15.1 5.1 0.09 13.6 5.1 1.9 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain PCI PF01399.27 EER28424.1 - 2.1e-12 47.5 0.0 5.2e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 EER28424.1 - 9.4e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.6 EER28424.1 - 0.011 16.2 4.0 3.2 8.3 0.2 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat SLAC1 PF03595.17 EER28425.1 - 3.3e-52 177.8 34.5 4.1e-52 177.5 34.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4064 PF13273.6 EER28425.1 - 3.6 7.9 12.3 1.8 8.9 0.8 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) WD40 PF00400.32 EER28426.1 - 4.3e-13 49.5 4.7 0.065 14.1 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER28426.1 - 0.0085 16.4 0.1 3.4 8.0 0.0 3.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain FAD_binding_2 PF00890.24 EER28428.1 - 1.1e-84 284.9 0.3 1.4e-84 284.6 0.3 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EER28428.1 - 5.5e-23 80.9 0.1 2.4e-20 72.4 0.1 3.7 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EER28428.1 - 8.6e-15 55.2 0.7 1.9e-14 54.0 0.7 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EER28428.1 - 1.7e-09 37.6 0.9 6.8e-09 35.6 0.9 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER28428.1 - 1.8e-08 34.5 1.7 3.9e-07 30.2 0.4 2.9 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EER28428.1 - 2.7e-08 33.4 0.4 1.1e-07 31.4 0.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER28428.1 - 1.5e-06 27.7 0.0 0.041 13.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER28428.1 - 5.9e-06 25.2 4.1 0.00016 20.5 1.1 3.0 2 1 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EER28428.1 - 4.2e-05 23.0 0.9 0.17 11.1 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 EER28428.1 - 0.00011 21.5 1.0 0.039 13.2 0.3 2.4 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EER28428.1 - 0.00025 20.2 1.3 0.18 10.9 0.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EER28428.1 - 0.00028 20.3 0.1 0.00049 19.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EER28428.1 - 0.02 14.2 0.2 0.036 13.4 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EER28428.1 - 0.021 15.4 1.9 4.7 7.8 0.2 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER28428.1 - 0.13 11.3 0.9 7.5 5.6 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Sin3a_C PF16879.5 EER28429.1 - 1.4e-80 271.1 0.0 1.4e-80 271.1 0.0 3.1 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 EER28429.1 - 8.9e-45 150.6 4.2 1.4e-17 63.5 0.0 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EER28429.1 - 6.6e-38 128.7 0.1 3e-37 126.6 0.1 2.2 1 0 0 1 1 1 1 Sin3 family co-repressor AcetylCoA_hydro PF02550.15 EER28430.1 - 1.9e-48 165.1 0.0 2.8e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EER28430.1 - 1.3e-40 138.9 0.0 2.3e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Abhydrolase_1 PF00561.20 EER28431.1 - 6.8e-10 39.0 0.7 1.4e-08 34.7 0.3 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Glyco_hydro_17 PF00332.18 EER28432.1 - 0.015 14.9 0.2 0.13 11.8 0.2 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 17 Penaeidin PF05927.11 EER28432.1 - 0.073 13.8 0.0 0.31 11.8 0.0 2.1 1 0 0 1 1 1 0 Penaeidin GARS_N PF02844.15 EER28432.1 - 0.12 13.2 0.0 0.4 11.5 0.0 1.9 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain ThiC-associated PF13667.6 EER28432.1 - 0.88 9.4 6.7 2.8 7.8 1.4 2.6 2 0 0 2 2 2 0 ThiC-associated domain APH PF01636.23 EER28433.1 - 5.9e-13 49.3 0.0 4.3e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EER28433.1 - 0.0086 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase DUF3759 PF12585.8 EER28434.1 - 0.037 14.0 4.8 0.086 12.9 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) Roughex PF06020.11 EER28434.1 - 0.82 8.7 4.6 1.2 8.2 4.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein WD40 PF00400.32 EER28435.1 - 0.00015 22.5 2.1 0.0034 18.2 0.1 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat PRAS PF15798.5 EER28435.1 - 0.039 14.5 1.3 0.28 11.8 0.6 2.4 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 Pre-PUA PF17832.1 EER28435.1 - 0.13 12.9 0.0 0.28 11.9 0.0 1.5 1 0 0 1 1 1 0 Pre-PUA-like domain Chitin_synth_2 PF03142.15 EER28436.1 - 3.4e-292 969.7 0.4 4.4e-292 969.4 0.4 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EER28436.1 - 2e-14 54.0 1.0 5e-14 52.7 1.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EER28436.1 - 2.2e-09 37.5 0.0 2.6e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EER28436.1 - 0.00038 20.0 0.0 0.0047 16.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EER28436.1 - 0.0028 17.5 0.0 0.68 9.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Cyt-b5 PF00173.28 EER28436.1 - 0.017 15.2 0.1 1.3 9.2 0.0 2.7 2 1 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain Sel1 PF08238.12 EER28437.1 - 1.7e-35 120.6 31.2 1.8e-05 25.2 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat TPR_6 PF13174.6 EER28437.1 - 0.2 12.4 8.4 2.6 8.9 0.2 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EER28437.1 - 0.55 10.8 6.1 9.8 6.8 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MFS_1 PF07690.16 EER28438.1 - 3.4e-40 138.0 61.9 2.8e-38 131.8 64.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER28438.1 - 1e-13 50.6 31.0 1.9e-13 49.7 31.0 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER28438.1 - 7.4e-13 48.2 10.9 7.4e-13 48.2 10.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Myosin_head PF00063.21 EER28439.1 - 3.5e-240 798.9 5.8 4.2e-240 798.6 5.8 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EER28439.1 - 2.9e-51 173.8 0.0 5.1e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EER28439.1 - 3e-14 52.3 0.0 7.7e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER28439.1 - 8.6e-09 35.1 0.1 3.1e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EER28439.1 - 2.4e-08 33.5 0.0 7.6e-08 31.9 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 EER28439.1 - 0.0071 16.1 7.5 0.49 10.3 0.6 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 EER28439.1 - 0.014 15.7 0.0 0.043 14.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 EER28439.1 - 0.019 14.5 0.5 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EER28439.1 - 0.026 14.9 0.0 0.082 13.3 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EER28439.1 - 0.092 12.9 0.0 7.1 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EER28439.1 - 0.13 12.6 0.0 0.43 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 EER28439.1 - 0.15 11.9 0.0 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain OPA3 PF07047.12 EER28440.1 - 1.3e-49 167.1 2.5 2.1e-49 166.4 2.5 1.4 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.9 EER28440.1 - 0.037 14.5 1.3 0.098 13.1 1.3 1.7 1 1 0 1 1 1 0 Mediator complex protein DUF3318 PF11780.8 EER28440.1 - 0.65 9.9 0.0 0.65 9.9 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3318) DUF2681 PF10883.8 EER28440.1 - 0.73 10.3 7.8 16 5.9 5.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF4472 PF14739.6 EER28440.1 - 0.92 10.3 10.4 0.4 11.4 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) Pkinase PF00069.25 EER28441.1 - 8.8e-69 231.8 0.0 1.3e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER28441.1 - 5.2e-44 150.5 0.0 8.3e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EER28441.1 - 4e-08 33.3 0.2 0.02 15.1 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EER28441.1 - 5.6e-06 25.9 0.0 3.4e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EER28441.1 - 0.022 13.7 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DHHC PF01529.20 EER28442.1 - 2e-32 112.1 5.4 2e-32 112.1 5.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DNA_mis_repair PF01119.19 EER28443.1 - 1.6e-09 37.5 0.0 4.7e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EER28443.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EER28443.1 - 2e-06 28.3 0.0 4.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SET PF00856.28 EER28444.1 - 6.6e-07 29.9 0.0 9.6e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 SET domain cobW PF02492.19 EER28445.1 - 1.8e-41 141.7 0.0 2.5e-41 141.2 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EER28445.1 - 0.0022 17.9 0.0 0.0064 16.4 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EER28445.1 - 0.027 14.8 0.0 0.096 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.14 EER28445.1 - 0.071 13.0 0.0 0.25 11.3 0.0 1.9 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.18 EER28445.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EER28445.1 - 0.14 12.0 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain Orn_Arg_deC_N PF02784.16 EER28446.1 - 9.6e-85 283.9 0.0 1.2e-84 283.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EER28446.1 - 5.4e-19 68.2 0.0 7.5e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EER28446.1 - 0.0031 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Methyltransf_16 PF10294.9 EER28447.1 - 4.4e-51 173.0 0.1 6.1e-51 172.6 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EER28447.1 - 2.2e-06 27.6 0.0 3.1e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER28447.1 - 7.6e-06 25.9 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER28447.1 - 1.1e-05 26.0 0.1 2.5e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EER28447.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 EER28447.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.15 EER28447.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.6 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_12 PF08242.12 EER28447.1 - 0.14 12.9 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DSBA PF01323.20 EER28449.1 - 8.7e-13 48.5 0.0 1e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain MIF4G_like_2 PF09090.11 EER28451.1 - 2.4 7.6 8.3 2.5 7.5 1.4 2.4 2 0 0 2 2 2 0 MIF4G like HAND PF09110.11 EER28451.1 - 3.2 8.6 9.2 5.1 7.9 4.1 2.5 2 0 0 2 2 2 0 HAND ALMT PF11744.8 EER28451.1 - 7.1 5.3 8.3 0.54 9.0 2.3 1.8 2 0 0 2 2 2 0 Aluminium activated malate transporter Mitofilin PF09731.9 EER28454.1 - 1.2e-152 510.0 31.0 8.3e-125 418.0 24.4 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein Ribosomal_L20 PF00453.18 EER28454.1 - 0.039 14.0 3.9 0.6 10.2 3.9 2.5 1 1 0 1 1 1 0 Ribosomal protein L20 Tox-REase-2 PF15646.6 EER28454.1 - 0.065 13.4 1.3 0.17 12.1 0.7 1.9 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 2 YqhG PF11079.8 EER28454.1 - 0.2 10.6 1.5 0.35 9.8 1.5 1.4 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function LepA_C PF06421.12 EER28454.1 - 0.55 10.4 5.8 0.68 10.1 1.0 2.7 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus Ras PF00071.22 EER28455.1 - 3e-59 199.3 0.2 3.4e-59 199.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER28455.1 - 1.3e-36 125.5 0.1 2.9e-36 124.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER28455.1 - 9.9e-15 54.4 0.0 1.2e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EER28455.1 - 7e-07 28.8 0.0 8.7e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EER28455.1 - 1.1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER28455.1 - 3.1e-06 26.9 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EER28455.1 - 1.7e-05 24.8 0.8 0.16 11.9 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EER28455.1 - 0.011 16.1 0.1 0.023 15.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EER28455.1 - 0.039 14.2 0.0 3 8.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain SRPRB PF09439.10 EER28455.1 - 0.086 12.3 0.1 0.2 11.1 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Syja_N PF02383.18 EER28456.1 - 9.7e-89 297.8 0.0 1.2e-88 297.5 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain FUN14 PF04930.15 EER28456.1 - 0.086 13.3 0.0 2.7 8.5 0.0 2.5 2 0 0 2 2 2 0 FUN14 family Mur_ligase_M PF08245.12 EER28457.1 - 4e-06 26.9 0.0 0.00079 19.5 0.0 3.3 1 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EER28457.1 - 0.13 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain NMT_C PF02799.15 EER28458.1 - 1.8e-90 302.1 0.0 2.7e-90 301.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EER28458.1 - 1.1e-74 249.6 0.0 6.7e-74 247.1 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EER28458.1 - 8.3e-07 29.1 0.0 2.8e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain ATP-grasp_5 PF13549.6 EER28458.1 - 0.024 14.1 0.1 2.7 7.4 0.1 2.4 2 0 0 2 2 2 0 ATP-grasp domain PUMA PF15826.5 EER28458.1 - 0.057 13.6 0.6 0.1 12.8 0.6 1.3 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis Acetyltransf_3 PF13302.7 EER28458.1 - 0.17 12.6 0.0 0.4 11.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TLD PF07534.16 EER28459.1 - 3e-17 63.2 0.0 5.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 TLD DUF1773 PF08593.10 EER28459.1 - 1.9e-05 25.6 2.3 6.5e-05 23.9 2.3 2.0 1 0 0 1 1 1 1 Domain of unknown function Abhydrolase_6 PF12697.7 EER28461.1 - 4.2e-10 40.6 0.4 7.9e-10 39.7 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER28461.1 - 3.1e-06 26.6 0.0 4.8e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EER28461.1 - 7.2e-06 26.0 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EER28461.1 - 6.8e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold GTP_EFTU PF00009.27 EER28462.1 - 1.4e-58 197.6 0.2 2.5e-58 196.8 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EER28462.1 - 1.2e-33 115.0 0.0 2.5e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EER28462.1 - 9.3e-33 112.6 0.0 1.7e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EER28462.1 - 2.7e-24 85.0 0.0 6.6e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EER28462.1 - 3.3e-12 46.6 0.1 7.6e-12 45.5 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EER28462.1 - 9.6e-07 28.7 0.0 2.3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EER28462.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribosomal_L36 PF00444.18 EER28463.1 - 1.3e-20 73.2 9.4 1.9e-20 72.8 9.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 PALP PF00291.25 EER28464.1 - 1.3e-76 257.8 0.6 1.7e-76 257.4 0.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EER28464.1 - 8.5e-43 144.0 0.0 1.8e-20 72.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 EER28465.1 - 1e-24 86.5 0.0 1.5e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Acetyltransf_1 PF00583.25 EER28466.1 - 8.5e-12 45.3 0.0 1.3e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER28466.1 - 7.3e-07 29.2 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER28466.1 - 2.2e-06 28.0 0.1 3.5e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER28466.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EER28466.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain cpYpsA PF12694.7 EER28466.1 - 0.18 11.6 0.0 0.76 9.6 0.0 1.9 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family PIG-U PF06728.13 EER28467.1 - 3.1e-109 365.5 18.7 2.6e-107 359.2 18.7 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.11 EER28468.1 - 2.4e-123 411.0 0.0 2.4e-123 411.0 0.0 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EER28468.1 - 0.00045 20.6 0.0 0.0029 18.0 0.0 2.2 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RRN9 PF10680.9 EER28469.1 - 2.4e-21 75.8 3.2 2.4e-21 75.8 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2_aberr PF17017.5 EER28469.1 - 0.26 11.4 0.3 0.67 10.1 0.1 1.7 2 0 0 2 2 2 0 Aberrant zinc-finger Aldedh PF00171.22 EER28471.1 - 2.4e-164 547.2 0.0 2.7e-164 547.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family KfrB PF18790.1 EER28471.1 - 0.12 12.6 0.1 22 5.4 0.0 3.2 3 0 0 3 3 3 0 KfrB protein Raffinose_syn PF05691.12 EER28472.1 - 1e-55 188.9 0.8 1.6e-52 178.4 1.9 3.2 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 tRNA-synt_1b PF00579.25 EER28473.1 - 1.5e-71 241.1 0.0 2.2e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EER28473.1 - 2.8e-44 149.8 0.0 5.3e-44 148.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 EER28473.1 - 0.043 13.5 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 S4 domain MutS_V PF00488.21 EER28474.1 - 3.5e-67 226.1 0.1 7e-67 225.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EER28474.1 - 1.8e-39 135.9 0.0 3.7e-39 134.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EER28474.1 - 1.9e-33 115.0 0.2 5.3e-33 113.6 0.0 1.8 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 EER28474.1 - 9.9e-15 55.0 0.0 2.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EER28474.1 - 1.7e-12 47.5 0.4 4.3e-12 46.2 0.4 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_21 PF13304.6 EER28474.1 - 0.0012 18.7 2.7 0.14 11.9 0.2 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EER28474.1 - 0.015 14.9 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EER28474.1 - 0.019 15.4 2.3 0.23 11.9 0.4 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EER28474.1 - 0.13 12.1 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cut12 PF11500.8 EER28474.1 - 0.29 11.1 2.3 3 7.8 1.6 2.6 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Rhodanese PF00581.20 EER28475.1 - 2.7e-09 37.5 0.0 3.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Pol_alpha_B_N PF08418.10 EER28476.1 - 0.017 15.1 1.5 0.02 14.9 1.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PAR1 PF06521.11 EER28476.1 - 0.056 13.1 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 PAR1 protein Peptidase_M28 PF04389.17 EER28478.1 - 1.2e-30 106.7 0.0 2.7e-30 105.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M28 Sulf_transp PF04143.14 EER28479.1 - 2.3e-05 24.1 4.2 2.3e-05 24.1 4.2 3.3 2 1 1 3 3 3 2 Sulphur transport MFS_5 PF05631.14 EER28479.1 - 0.021 13.7 0.0 2.3 7.0 0.1 2.1 1 1 1 2 2 2 0 Sugar-tranasporters, 12 TM Tmemb_14 PF03647.13 EER28479.1 - 0.14 12.9 4.4 2.8 8.7 0.6 3.3 3 0 0 3 3 3 0 Transmembrane proteins 14C LigD_N PF13298.6 EER28480.1 - 3.4e-30 104.4 0.0 2.1e-29 101.9 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) ABC_tran PF00005.27 EER28481.1 - 1.1e-47 162.0 0.0 2.4e-28 99.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EER28481.1 - 8.5e-37 127.3 31.0 4.9e-27 95.3 12.9 3.3 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.19 EER28481.1 - 6.6e-10 38.8 0.0 0.028 13.9 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EER28481.1 - 0.00014 21.5 0.4 0.044 13.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EER28481.1 - 0.0005 20.4 0.1 2.9 8.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EER28481.1 - 0.00051 20.1 0.2 0.18 11.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EER28481.1 - 0.00051 20.6 2.5 0.011 16.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EER28481.1 - 0.00099 19.5 0.0 0.99 9.8 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EER28481.1 - 0.0016 18.4 0.0 1.7 8.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 EER28481.1 - 0.0021 18.2 1.3 0.89 9.6 0.1 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain T2SSE PF00437.20 EER28481.1 - 0.0025 16.9 0.0 0.23 10.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EER28481.1 - 0.016 15.0 0.2 1 9.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_21 PF13304.6 EER28481.1 - 0.016 15.0 0.2 11 5.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 EER28481.1 - 0.19 10.9 0.2 1.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EER28481.1 - 0.54 10.3 1.7 29 4.7 0.6 2.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EER28481.1 - 0.77 9.7 2.6 1.9 8.3 0.3 2.6 3 0 0 3 3 2 0 NACHT domain PEP_mutase PF13714.6 EER28482.1 - 1e-62 211.7 3.4 1.2e-62 211.5 3.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase tRNA-synt_2 PF00152.20 EER28483.1 - 4.3e-90 302.0 0.0 5.9e-90 301.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EER28483.1 - 0.0086 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) CS PF04969.16 EER28484.1 - 1.6e-16 61.1 0.1 3.2e-16 60.1 0.0 1.6 2 0 0 2 2 2 1 CS domain Spt5-NGN PF03439.13 EER28485.1 - 9.4e-24 83.1 0.0 1.6e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.7 EER28485.1 - 1.3e-17 64.1 17.1 1.3e-17 64.1 17.1 3.4 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.8 EER28485.1 - 5.7e-16 59.3 13.2 5.7e-16 59.3 13.2 4.3 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EER28485.1 - 1.8e-14 53.1 17.9 0.0019 18.1 0.0 5.2 5 0 0 5 5 5 4 KOW motif DUF3912 PF13051.6 EER28485.1 - 0.0001 22.4 4.6 0.0074 16.5 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3912) Lin-8 PF03353.15 EER28485.1 - 1.9 8.0 12.7 2.8 7.4 12.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Acyl-CoA_dh_1 PF00441.24 EER28486.1 - 2e-42 144.9 0.4 2.7e-42 144.5 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EER28486.1 - 4.2e-22 78.1 0.1 7.3e-22 77.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EER28486.1 - 4.1e-20 72.5 0.0 1.2e-19 71.1 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.28 EER28486.1 - 6.6e-20 71.0 0.1 1.2e-19 70.2 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.11 EER28486.1 - 6.1e-11 42.7 0.0 9.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RPN2_C PF18004.1 EER28487.1 - 6.4e-56 188.7 7.0 6.4e-56 188.7 7.0 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EER28487.1 - 4.2e-33 112.1 20.0 4.9e-09 36.2 0.0 8.6 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EER28487.1 - 4.9e-21 74.9 0.4 1.8e-14 53.9 0.0 4.8 4 1 3 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 EER28487.1 - 1.4e-06 28.6 0.2 0.00013 22.3 0.1 4.1 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EER28487.1 - 1.8e-05 24.6 1.4 1.9 9.0 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 EER28487.1 - 0.0011 19.1 0.0 0.13 12.3 0.0 2.8 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EER28487.1 - 0.1 13.3 1.4 1.9 9.4 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Seryl_tRNA_N PF02403.22 EER28488.1 - 0.0022 18.2 11.6 0.29 11.4 3.2 3.5 3 1 0 3 3 3 2 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.10 EER28488.1 - 0.015 15.5 1.4 0.015 15.5 1.4 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 EER28488.1 - 0.018 15.5 10.1 0.12 12.9 5.9 3.0 3 1 0 3 3 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EER28488.1 - 0.028 14.6 8.3 0.47 10.7 4.1 2.7 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EER28488.1 - 0.039 13.7 0.9 0.039 13.7 0.9 2.6 3 0 0 3 3 2 0 Septum formation initiator DUF1664 PF07889.12 EER28488.1 - 0.05 13.6 7.6 0.036 14.1 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 EER28488.1 - 0.059 12.7 0.9 0.095 12.0 0.2 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein GAS PF13851.6 EER28488.1 - 0.062 12.6 9.2 0.24 10.8 2.9 2.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding AAA_13 PF13166.6 EER28488.1 - 0.068 11.8 5.0 0.13 10.9 2.3 2.1 2 0 0 2 2 2 0 AAA domain Baculo_PEP_C PF04513.12 EER28488.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.5 3 1 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec5 PF15469.6 EER28488.1 - 0.13 12.0 4.8 3.8 7.3 1.1 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec5 Isy1 PF06246.12 EER28488.1 - 0.13 11.8 2.1 0.11 12.0 0.2 1.8 2 0 0 2 2 2 0 Isy1-like splicing family DUF724 PF05266.14 EER28488.1 - 0.14 12.0 5.9 0.092 12.6 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) SKA1 PF07160.12 EER28488.1 - 0.24 11.2 5.4 0.46 10.3 1.8 2.4 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Raco_middle PF17651.1 EER28488.1 - 0.3 10.8 0.9 0.43 10.2 0.1 1.5 2 0 0 2 2 1 0 RACo middle region Tropomyosin_1 PF12718.7 EER28488.1 - 0.32 11.1 7.5 0.33 11.1 3.5 2.3 2 0 0 2 2 2 0 Tropomyosin like Sec34 PF04136.15 EER28488.1 - 0.39 10.6 5.5 0.66 9.8 2.6 2.6 3 0 0 3 3 2 0 Sec34-like family DUF5082 PF16888.5 EER28488.1 - 0.47 10.7 7.5 0.63 10.3 0.9 3.0 2 1 0 3 3 2 0 Domain of unknown function (DUF5082) CENP-F_leu_zip PF10473.9 EER28488.1 - 0.49 10.4 11.6 0.14 12.2 4.4 2.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 EER28488.1 - 0.51 8.9 3.3 0.46 9.0 2.3 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Leu_zip PF15294.6 EER28488.1 - 0.62 9.5 9.1 0.26 10.8 2.8 2.2 2 0 0 2 2 2 0 Leucine zipper Tup_N PF08581.10 EER28488.1 - 0.62 10.4 7.1 0.074 13.4 1.6 2.3 2 0 0 2 2 2 0 Tup N-terminal STAT_alpha PF01017.20 EER28488.1 - 0.67 9.8 6.5 0.13 12.2 1.7 2.1 3 0 0 3 3 3 0 STAT protein, all-alpha domain Lectin_N PF03954.14 EER28488.1 - 0.82 9.4 8.3 1.7 8.4 2.5 2.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain JIP_LZII PF16471.5 EER28488.1 - 0.85 9.8 6.4 0.62 10.3 1.7 2.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Cep57_MT_bd PF06657.13 EER28488.1 - 1.3 9.6 7.1 0.36 11.3 1.3 2.9 3 0 0 3 3 2 0 Centrosome microtubule-binding domain of Cep57 Mod_r PF07200.13 EER28488.1 - 1.3 9.1 8.9 1.3 9.1 5.9 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein L31 PF09784.9 EER28488.1 - 1.5 9.2 4.4 8.2 6.9 0.1 3.3 2 2 1 3 3 3 0 Mitochondrial ribosomal protein L31 HALZ PF02183.18 EER28488.1 - 1.6 9.0 6.2 0.17 12.1 0.9 2.1 2 0 0 2 2 1 0 Homeobox associated leucine zipper Spc7 PF08317.11 EER28488.1 - 1.7 7.5 10.9 0.48 9.2 4.3 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 EER28488.1 - 3.8 7.7 13.7 0.66 10.2 5.8 2.7 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 TolA_bind_tri PF16331.5 EER28488.1 - 5.3 7.2 10.3 0.16 12.1 1.7 2.6 3 0 0 3 3 2 0 TolA binding protein trimerisation FlaC_arch PF05377.11 EER28488.1 - 6 7.3 6.5 1.3 9.5 0.5 2.9 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 EER28488.1 - 6.1 7.3 15.6 0.048 14.1 3.7 2.9 3 1 0 3 3 2 0 Centromere protein H (CENP-H) Spc24 PF08286.11 EER28488.1 - 7.7 6.8 8.3 2.1 8.6 2.2 2.8 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 DUF3336 PF11815.8 EER28490.1 - 1.8e-33 115.2 0.5 3.4e-33 114.3 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EER28490.1 - 4.6e-18 66.1 0.1 1e-17 65.0 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.16 EER28491.1 - 3.9e-26 91.8 34.9 5.3e-26 91.4 27.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER28491.1 - 6.2e-09 35.2 4.9 6.2e-09 35.2 4.9 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2721 PF11026.8 EER28491.1 - 0.54 10.1 0.0 0.54 10.1 0.0 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2721) TMEM171 PF15471.6 EER28492.1 - 0.27 10.2 0.0 0.27 10.2 0.0 1.5 2 0 0 2 2 2 0 Transmembrane protein family 171 Mid2 PF04478.12 EER28492.1 - 0.27 11.1 0.0 0.5 10.2 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor RCR PF12273.8 EER28493.1 - 0.00054 20.6 0.2 0.0011 19.6 0.2 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.6 EER28493.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family TMEM52 PF14979.6 EER28493.1 - 0.031 14.2 0.3 0.074 13.0 0.3 1.6 1 0 0 1 1 1 0 Transmembrane 52 DUF4448 PF14610.6 EER28493.1 - 0.055 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 EER28493.1 - 0.17 12.8 0.0 0.34 11.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain OTT_1508_deam PF14441.6 EER28493.1 - 5.2 7.2 6.1 2.7 8.1 2.6 2.2 2 0 0 2 2 2 0 OTT_1508-like deaminase Med8 PF10232.9 EER28494.1 - 1.6e-70 237.3 0.5 1.8e-70 237.1 0.5 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF4702 PF15774.5 EER28494.1 - 0.048 12.6 0.5 0.066 12.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) RNA_pol_3_Rpc31 PF11705.8 EER28494.1 - 0.061 13.6 5.0 0.084 13.1 5.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.10 EER28494.1 - 0.78 10.2 6.9 1.6 9.1 6.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.13 EER28494.1 - 0.82 9.5 8.7 1.7 8.5 8.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.12 EER28494.1 - 1.7 7.9 5.3 2.7 7.2 5.3 1.2 1 0 0 1 1 1 0 NOA36 protein PQ-loop PF04193.14 EER28495.1 - 1.3e-19 69.7 10.5 1.4e-11 44.0 0.9 3.0 3 0 0 3 3 3 2 PQ loop repeat UbiA PF01040.18 EER28496.1 - 8.1e-57 192.4 19.3 8.1e-57 192.4 19.3 1.7 1 1 1 2 2 2 1 UbiA prenyltransferase family Zn_clus PF00172.18 EER28497.1 - 3.6e-09 36.6 9.4 9e-09 35.3 9.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EER28497.1 - 1.3e-08 34.1 0.5 1.9e-08 33.5 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box PF00646.33 EER28498.1 - 0.081 12.8 5.7 0.12 12.3 0.3 3.1 3 0 0 3 3 3 0 F-box domain GFD1 PF17331.2 EER28498.1 - 1.7 8.9 3.5 1.6 9.0 1.3 2.1 2 0 0 2 2 2 0 GFD1 mRNA transport factor CTP_transf_like PF01467.26 EER28499.1 - 4.4e-05 23.7 0.0 0.0002 21.6 0.0 2.1 2 1 0 2 2 2 1 Cytidylyltransferase-like WD40 PF00400.32 EER28500.1 - 6.6e-13 48.9 5.2 0.00016 22.4 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat mRNA_triPase PF02940.15 EER28501.1 - 1.5e-60 204.6 0.0 2.8e-60 203.8 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Kelch_4 PF13418.6 EER28502.1 - 1.2e-16 60.4 1.7 5.7e-06 26.2 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EER28502.1 - 1.2e-13 51.0 7.5 2.1e-08 34.2 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EER28502.1 - 9.6e-13 47.8 1.0 0.00084 19.3 0.4 4.5 3 1 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 EER28502.1 - 5.7e-11 41.8 0.0 0.013 15.0 0.0 4.3 3 1 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EER28502.1 - 1.2e-10 41.3 4.5 0.081 13.2 0.0 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EER28502.1 - 7.6e-08 32.0 0.9 0.0036 17.2 0.0 4.4 3 1 0 3 3 3 2 Kelch motif MFS_1 PF07690.16 EER28503.1 - 2.3e-22 79.4 16.4 2.3e-22 79.4 16.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER28503.1 - 4.4e-06 25.8 3.3 4.4e-06 25.8 3.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 EER28503.1 - 0.0011 17.9 0.0 0.0011 17.9 0.0 3.2 1 1 0 2 2 2 1 MFS_1 like family Antimicrobial24 PF16049.5 EER28503.1 - 2.2 8.3 4.3 6.3 6.9 0.5 2.6 2 0 0 2 2 2 0 Frog antimicrobial peptide Aldo_ket_red PF00248.21 EER28504.1 - 5.5e-44 150.5 0.0 1.1e-43 149.6 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family ANAPC4_WD40 PF12894.7 EER28505.1 - 6.4e-08 32.8 0.6 2.6 8.4 0.0 5.6 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain DUF676 PF05057.14 EER28505.1 - 2.3e-05 24.0 0.3 5.1e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NACHT PF05729.12 EER28505.1 - 3.4e-05 23.8 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.13 EER28505.1 - 0.0021 17.8 0.3 0.0039 16.9 0.3 1.3 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.6 EER28505.1 - 0.0031 17.8 0.0 0.0086 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain WD40 PF00400.32 EER28505.1 - 0.0097 16.7 6.1 1.1e+02 3.9 0.0 7.2 6 1 1 7 7 6 0 WD domain, G-beta repeat AAA_16 PF13191.6 EER28505.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF829 PF05705.14 EER28505.1 - 0.081 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) APS_kinase PF01583.20 EER28505.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 EER28505.1 - 0.11 12.5 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 EER28505.1 - 0.15 11.3 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Fructosamin_kin PF03881.14 EER28506.1 - 4.2e-36 124.6 0.0 6.6e-36 124.0 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EER28506.1 - 8.3e-05 22.6 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family AhpC-TSA PF00578.21 EER28507.1 - 7.9e-26 90.4 0.0 4.4e-21 75.1 0.0 2.6 2 1 1 3 3 3 2 AhpC/TSA family 1-cysPrx_C PF10417.9 EER28507.1 - 1e-11 44.5 0.1 2.1e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EER28507.1 - 7.5e-11 41.9 0.0 3.5e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Redoxin MFS_1 PF07690.16 EER28508.1 - 1.7e-42 145.6 25.5 1.7e-42 145.6 25.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EER28508.1 - 1.5e-08 33.6 4.8 2.3e-08 33.0 4.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER28508.1 - 2.9e-08 33.0 17.7 1.3e-07 30.9 17.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EER28508.1 - 0.065 11.6 4.1 0.021 13.3 1.5 1.4 2 0 0 2 2 2 0 Transmembrane secretion effector APH PF01636.23 EER28509.1 - 0.0011 18.9 0.0 0.0029 17.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family HTH_AsnC-type PF13404.6 EER28509.1 - 0.17 11.7 0.7 0.36 10.7 0.7 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Methyltransf_PK PF05891.12 EER28510.1 - 5.4e-75 251.7 0.0 6.1e-75 251.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 EER28510.1 - 9.8e-05 22.2 0.0 0.00025 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EER28510.1 - 0.00014 21.2 0.1 0.00038 19.8 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EER28510.1 - 0.00015 22.4 0.0 0.00023 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER28510.1 - 0.0066 17.1 0.1 0.011 16.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain EVE PF01878.18 EER28511.1 - 8.8e-50 168.5 0.1 1.5e-49 167.7 0.1 1.4 1 0 0 1 1 1 1 EVE domain Aldedh PF00171.22 EER28512.1 - 5.3e-181 602.2 1.5 6e-181 602.0 1.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DDE_1 PF03184.19 EER28513.1 - 7e-22 77.9 0.0 5.4e-21 75.0 0.0 2.2 2 0 0 2 2 2 1 DDE superfamily endonuclease Asp-B-Hydro_N PF05279.11 EER28513.1 - 0.14 12.2 17.3 0.2 11.7 17.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region GREB1 PF15782.5 EER28513.1 - 9.5 3.2 11.8 11 2.9 11.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DIOX_N PF14226.6 EER28514.1 - 2.1e-32 112.4 0.0 5e-32 111.1 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EER28514.1 - 3.5e-14 53.1 0.0 6.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NmrA PF05368.13 EER28515.1 - 3.5e-58 196.9 0.1 4.4e-58 196.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EER28515.1 - 1.9e-13 50.7 0.0 2.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EER28515.1 - 0.0026 18.0 0.3 0.16 12.2 0.1 2.4 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EER28515.1 - 0.029 13.4 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EER28515.1 - 0.12 11.8 0.0 0.27 10.6 0.1 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EER28516.1 - 1.6e-44 152.3 43.0 3.3e-44 151.2 43.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EER28516.1 - 3.1e-09 35.8 24.1 1.2e-08 33.9 24.1 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CENP-T_N PF16171.5 EER28516.1 - 0.36 9.7 0.0 0.52 9.2 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T N-terminus Fungal_trans PF04082.18 EER28517.1 - 5.7e-15 55.1 0.0 8.7e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28517.1 - 8.6e-10 38.6 10.4 1.4e-09 37.9 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.23 EER28518.1 - 1.4e-09 38.1 12.2 1.9e-09 37.7 12.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Glyco_hydro_76 PF03663.14 EER28519.1 - 5.1e-160 533.0 6.6 6.2e-160 532.7 6.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EER28519.1 - 0.0002 20.5 4.8 0.42 9.6 0.2 3.4 3 0 0 3 3 3 3 Glycosyl Hydrolase Family 88 PFK PF00365.20 EER28520.1 - 1.1e-192 638.6 0.1 5.1e-105 350.9 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 EER28520.1 - 0.033 13.8 0.1 0.11 12.2 0.1 1.9 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain UVR PF02151.19 EER28520.1 - 0.07 12.9 0.8 0.2 11.4 0.8 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif IBR PF01485.21 EER28521.1 - 6.3e-15 55.1 47.3 4.7e-09 36.3 6.2 4.7 4 0 0 4 4 4 3 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EER28521.1 - 0.0029 17.6 2.6 0.0029 17.6 2.6 4.0 4 1 0 4 4 4 1 RING-type zinc-finger zf-RING_2 PF13639.6 EER28521.1 - 0.0064 16.8 5.3 0.0064 16.8 5.3 4.8 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 EER28521.1 - 0.0066 16.3 2.4 0.0066 16.3 2.4 5.1 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EER28521.1 - 0.0087 16.2 1.3 0.0087 16.2 1.3 5.1 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING Med17 PF10156.9 EER28522.1 - 3.2e-94 316.3 0.0 4.4e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Phage-MuB_C PF09077.11 EER28522.1 - 0.14 12.0 0.3 4.9 7.1 0.0 2.8 3 0 0 3 3 3 0 Mu B transposition protein, C terminal ISN1 PF06437.11 EER28523.1 - 1e-197 657.1 0.0 1.1e-197 656.9 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase HTH_Mga PF08280.11 EER28523.1 - 0.14 12.2 0.0 2 8.5 0.0 2.3 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain Ank_2 PF12796.7 EER28524.1 - 2e-55 185.3 4.5 1.2e-08 35.4 0.2 10.2 4 2 6 11 11 11 9 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EER28524.1 - 9.3e-39 127.0 12.1 0.0012 19.1 0.0 17.1 19 0 0 19 19 19 8 Ankyrin repeat Ank_4 PF13637.6 EER28524.1 - 1.7e-29 101.8 4.7 4.6e-06 27.1 0.0 12.0 8 3 5 13 13 13 8 Ankyrin repeats (many copies) Ank PF00023.30 EER28524.1 - 8.5e-29 98.7 21.4 0.0023 18.3 0.0 13.9 13 1 1 14 14 14 7 Ankyrin repeat Ank_5 PF13857.6 EER28524.1 - 3.4e-23 81.4 10.2 0.033 14.5 0.0 12.3 10 1 2 12 12 12 5 Ankyrin repeats (many copies) Clr5 PF14420.6 EER28524.1 - 2.1e-18 66.3 0.2 5.9e-17 61.6 0.1 2.7 3 0 0 3 3 3 1 Clr5 domain cNMP_binding PF00027.29 EER28525.1 - 5.2e-29 100.2 1.1 5.3e-18 64.9 0.0 6.1 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EER28525.1 - 6.2e-17 62.5 9.3 6.8e-16 59.1 7.4 2.8 2 1 0 2 2 2 1 Patatin-like phospholipase zinc_ribbon_10 PF10058.9 EER28527.1 - 1.1e-19 69.8 0.1 1.9e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein GRIP PF01465.20 EER28528.1 - 7.5e-17 61.0 0.1 1.6e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 GRIP domain TPR_MLP1_2 PF07926.12 EER28528.1 - 2.4e-08 34.1 149.0 0.0015 18.6 8.9 10.5 3 2 8 11 11 11 7 TPR/MLP1/MLP2-like protein HMMR_N PF15905.5 EER28528.1 - 6.1e-06 25.9 127.3 0.016 14.7 24.5 7.8 3 2 4 7 7 7 5 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 EER28528.1 - 1.3e-05 24.9 130.0 0.00047 19.8 49.4 7.3 3 2 4 7 7 7 5 Intermediate filament protein Myosin_tail_1 PF01576.19 EER28528.1 - 0.00013 19.9 80.0 0.00013 19.9 80.0 3.9 3 1 1 4 4 4 3 Myosin tail Macoilin PF09726.9 EER28528.1 - 0.00054 18.7 7.7 0.00054 18.7 7.7 4.6 1 1 3 5 5 4 3 Macoilin family Cast PF10174.9 EER28528.1 - 0.00076 17.9 28.5 0.00076 17.9 28.5 4.6 2 1 4 6 6 5 3 RIM-binding protein of the cytomatrix active zone Fez1 PF06818.15 EER28528.1 - 0.00076 20.0 135.9 0.013 16.0 16.3 8.3 2 1 8 10 10 10 2 Fez1 CALCOCO1 PF07888.11 EER28528.1 - 0.0013 17.7 30.1 0.0013 17.7 30.1 5.7 3 2 2 5 5 5 2 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 EER28528.1 - 0.0016 17.4 141.0 0.013 14.4 10.4 8.0 3 2 4 8 8 8 6 Spc7 kinetochore protein GAS PF13851.6 EER28528.1 - 0.003 17.0 137.1 0.41 10.0 6.5 9.4 3 3 4 8 8 8 3 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EER28528.1 - 0.0032 17.7 6.4 0.0032 17.7 6.4 9.0 3 2 5 8 8 7 2 Autophagy protein 16 (ATG16) DUF1192 PF06698.11 EER28528.1 - 0.0045 17.0 1.3 0.0045 17.0 1.3 8.7 9 0 0 9 9 8 1 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.9 EER28528.1 - 0.0045 17.0 150.8 0.028 14.5 4.6 9.8 3 2 7 10 10 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlxA PF14282.6 EER28528.1 - 0.0098 15.9 2.9 0.0098 15.9 2.9 9.8 4 3 4 9 9 5 1 FlxA-like protein Baculo_PEP_C PF04513.12 EER28528.1 - 0.045 13.8 47.0 0.13 12.3 4.1 7.8 3 2 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus DivIC PF04977.15 EER28528.1 - 0.1 12.4 0.1 0.1 12.4 0.1 14.7 6 4 10 16 16 16 0 Septum formation initiator EzrA PF06160.12 EER28528.1 - 0.16 10.1 107.2 0.42 8.7 57.3 5.5 3 2 2 5 5 5 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.10 EER28528.1 - 0.29 11.3 87.3 2.3 8.4 6.9 9.0 3 2 4 9 9 9 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 EER28528.1 - 0.35 11.4 162.7 0.074 13.6 9.5 10.9 3 2 7 10 10 8 0 Apg6 coiled-coil region DUF16 PF01519.16 EER28528.1 - 0.41 11.2 0.0 0.41 11.2 0.0 8.9 3 2 4 7 7 7 0 Protein of unknown function DUF16 MAD PF05557.13 EER28528.1 - 0.46 8.8 135.9 0.077 11.4 7.9 5.4 3 2 3 6 6 6 0 Mitotic checkpoint protein MscS_porin PF12795.7 EER28528.1 - 0.62 9.6 133.0 0.068 12.7 17.5 7.8 5 2 3 8 8 8 0 Mechanosensitive ion channel porin domain Desmo_N PF06771.11 EER28528.1 - 0.91 9.9 7.0 7 7.1 0.2 4.2 4 0 0 4 4 3 0 Viral Desmoplakin N-terminus FapA PF03961.13 EER28528.1 - 1.7 7.1 90.9 0.76 8.3 16.5 7.1 3 2 4 7 7 7 0 Flagellar Assembly Protein A VGPC1_C PF16799.5 EER28528.1 - 3.3 7.8 16.2 0.33 11.0 0.3 4.4 4 0 0 4 4 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 AAA_13 PF13166.6 EER28528.1 - 9.1 4.8 104.9 0.074 11.7 29.3 5.4 3 2 2 5 5 5 0 AAA domain Acetyltransf_1 PF00583.25 EER28529.1 - 3.5e-18 66.0 0.0 4.4e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EER28529.1 - 9.8e-09 35.1 0.0 1.5e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EER28529.1 - 2e-07 31.3 0.0 2.8e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EER28529.1 - 3.9e-07 30.8 0.0 5.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER28529.1 - 6.3e-07 29.4 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER28529.1 - 0.015 15.4 0.1 0.4 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EER28529.1 - 0.029 13.9 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_4 PF13420.7 EER28529.1 - 0.04 14.0 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER28529.1 - 0.04 14.0 0.0 0.067 13.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Anoctamin PF04547.12 EER28530.1 - 4e-112 375.3 3.4 5.1e-112 375.0 3.4 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ECF_trnsprt PF12822.7 EER28530.1 - 0.068 13.3 7.3 0.0098 16.0 2.9 2.0 2 1 0 2 2 2 0 ECF transporter, substrate-specific component bZIP_1 PF00170.21 EER28531.1 - 1.3e-07 31.6 8.0 3.9e-07 30.1 8.0 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EER28531.1 - 0.38 10.9 11.5 15 5.7 10.7 3.1 2 1 0 2 2 2 0 Basic region leucine zipper Zip PF02535.22 EER28531.1 - 8.9 5.4 5.9 14 4.8 5.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Actin PF00022.19 EER28532.1 - 6.4e-55 186.4 0.0 8.9e-29 100.3 0.0 2.5 2 1 0 2 2 2 2 Actin YL1_C PF08265.11 EER28533.1 - 2.2e-16 59.3 1.4 2.5e-16 59.1 0.3 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain LAT PF15234.6 EER28533.1 - 0.62 9.7 3.0 0.7 9.6 2.4 1.6 1 1 0 1 1 1 0 Linker for activation of T-cells Got1 PF04178.12 EER28534.1 - 2.7e-13 50.3 15.0 3.4e-13 50.0 15.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4418 PF14387.6 EER28534.1 - 0.15 12.3 2.2 0.49 10.6 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) Profilin PF00235.19 EER28535.1 - 2.2e-49 166.9 0.0 2.4e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Profilin Sec63 PF02889.16 EER28537.1 - 2.5e-128 426.6 0.0 1.5e-77 260.3 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EER28537.1 - 1.2e-52 178.3 0.2 8.1e-27 94.1 0.7 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 EER28537.1 - 1.2e-21 77.5 0.0 1.5e-10 41.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EER28537.1 - 2.2e-15 56.9 0.1 7.4e-07 29.5 0.0 4.6 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EER28537.1 - 9.4e-08 32.4 0.3 0.0029 17.9 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EER28537.1 - 1.1e-06 28.5 0.1 0.029 14.1 0.3 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EER28537.1 - 2.9e-05 24.4 0.6 0.0088 16.4 0.7 2.8 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 EER28537.1 - 0.00029 21.0 0.1 0.0008 19.6 0.1 1.7 1 0 0 1 1 1 1 N-terminal helicase PWI domain T2SSE PF00437.20 EER28537.1 - 0.01 14.9 0.0 1.5 7.8 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 EER28537.1 - 0.091 12.2 0.3 16 4.8 0.1 3.5 3 0 0 3 3 3 0 Bacterial TniB protein IstB_IS21 PF01695.17 EER28537.1 - 0.1 12.4 0.0 14 5.4 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_7 PF12775.7 EER28537.1 - 0.16 11.4 0.1 18 4.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Synaptobrevin PF00957.21 EER28538.1 - 9e-14 51.0 0.2 1.4e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EER28538.1 - 8e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain HD_2 PF12917.7 EER28540.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Ras PF00071.22 EER28541.1 - 5.9e-40 136.5 0.0 3.5e-37 127.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EER28541.1 - 1.7e-31 108.9 0.0 2.7e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER28541.1 - 3e-11 43.1 0.0 4.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EER28541.1 - 0.00011 22.2 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EER28541.1 - 0.00092 18.7 0.1 0.0017 17.8 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EER28541.1 - 0.0019 17.6 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EER28541.1 - 0.0022 18.4 0.0 0.004 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 EER28541.1 - 0.022 14.5 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EER28541.1 - 0.041 14.2 0.3 0.11 12.8 0.1 1.9 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EER28541.1 - 0.058 13.3 0.1 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 EER28541.1 - 0.061 13.4 0.0 0.12 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EER28541.1 - 0.064 13.5 0.9 0.17 12.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EER28541.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EER28541.1 - 0.078 12.5 0.3 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EER28541.1 - 0.15 12.3 0.5 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EER28541.1 - 0.16 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF3433 PF11915.8 EER28542.1 - 4.6e-38 129.6 13.1 3.3e-19 69.1 1.1 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) AAA PF00004.29 EER28543.1 - 6.4e-16 59.0 0.0 1.2e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EER28543.1 - 0.00028 21.3 0.0 0.0008 19.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EER28543.1 - 0.00074 19.7 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zot PF05707.12 EER28543.1 - 0.0075 15.9 0.1 0.39 10.3 0.0 2.2 1 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.6 EER28543.1 - 0.014 15.7 0.8 0.085 13.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.14 EER28543.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 EER28543.1 - 0.22 10.7 0.2 0.59 9.3 0.1 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Clr5 PF14420.6 EER28544.1 - 6.6e-19 67.9 4.2 2.1e-18 66.3 4.2 1.9 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.6 EER28544.1 - 9.9e-16 57.8 9.4 3.6e-06 27.2 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 EER28544.1 - 0.00028 20.6 1.9 2.7 8.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EER28544.1 - 0.00028 20.3 10.7 0.23 10.8 0.6 3.1 2 1 1 3 3 3 3 MalT-like TPR region TPR_7 PF13176.6 EER28544.1 - 0.014 15.4 6.3 13 6.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EER28544.1 - 0.026 14.6 4.9 4.5 7.6 0.5 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EER28544.1 - 1.7 9.4 7.4 1.8 9.3 1.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EER28544.1 - 1.8 9.1 9.0 0.8 10.3 2.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ADH_zinc_N PF00107.26 EER28545.1 - 5.8e-23 81.3 0.1 1.3e-22 80.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER28545.1 - 2.8e-20 72.2 0.5 5.2e-20 71.4 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EER28545.1 - 8.5e-12 45.0 0.2 1.7e-11 44.0 0.2 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EER28545.1 - 1.1e-08 36.1 0.0 2.7e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EER28545.1 - 0.0043 16.4 0.1 0.007 15.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EER28545.1 - 0.0061 15.9 0.5 0.011 15.1 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 EER28545.1 - 0.02 14.5 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ThiF PF00899.21 EER28545.1 - 0.044 13.1 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 ThiF family FMN_dh PF01070.18 EER28546.1 - 1e-120 403.0 0.0 1.2e-120 402.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EER28546.1 - 2.2e-22 78.9 0.0 4.8e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EER28546.1 - 2.1e-07 30.5 0.0 3.3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EER28546.1 - 9.8e-05 21.5 0.1 0.00027 20.1 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EER28546.1 - 0.00013 21.4 0.2 0.00023 20.7 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ENOD93 PF03386.14 EER28546.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein His_biosynth PF00977.21 EER28546.1 - 0.14 11.6 0.2 0.47 9.9 0.1 1.8 1 1 0 1 1 1 0 Histidine biosynthesis protein Bud13 PF09736.9 EER28547.1 - 1.1e-48 165.3 7.6 1.1e-48 165.3 7.6 3.1 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF2149 PF09919.9 EER28547.1 - 0.083 13.2 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Pkinase PF00069.25 EER28549.1 - 2.1e-41 142.0 0.0 1.4e-22 80.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER28549.1 - 1.1e-13 51.0 0.1 2.4e-09 36.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER28549.1 - 0.069 11.9 0.5 0.12 11.2 0.2 1.6 1 1 1 2 2 2 0 Fungal protein kinase Metallophos PF00149.28 EER28550.1 - 8.9e-13 49.2 1.7 1.7e-12 48.3 1.7 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EER28550.1 - 0.00024 21.3 1.2 0.0017 18.6 1.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DNA_binding_1 PF01035.20 EER28552.1 - 7.8e-25 86.8 0.1 9.8e-25 86.5 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain CLU PF13236.6 EER28552.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Clustered mitochondria Fungal_trans_2 PF11951.8 EER28554.1 - 7e-67 225.9 5.9 7.9e-67 225.7 5.9 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3176 PF11374.8 EER28554.1 - 0.018 15.2 2.4 3.3 8.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) NmrA PF05368.13 EER28555.1 - 5e-18 65.5 0.0 6.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EER28555.1 - 3.5e-17 62.9 0.1 1.9e-16 60.5 0.0 2.0 2 1 0 2 2 2 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EER28555.1 - 8.6e-10 39.0 0.1 8.6e-09 35.7 0.0 2.2 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EER28555.1 - 3.6e-05 23.3 0.2 0.0083 15.6 0.0 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EER28555.1 - 4.1e-05 24.1 0.0 0.00015 22.3 0.0 2.0 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EER28555.1 - 0.00022 21.3 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EER28555.1 - 0.00025 21.3 0.0 0.0006 20.1 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain PglD_N PF17836.1 EER28555.1 - 0.00026 21.6 0.2 0.018 15.7 0.0 2.4 2 0 0 2 2 2 1 PglD N-terminal domain ApbA PF02558.16 EER28555.1 - 0.00033 20.3 0.0 0.0007 19.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EER28555.1 - 0.00035 21.0 0.1 0.00094 19.6 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox PF00070.27 EER28555.1 - 0.0017 18.9 0.4 0.0036 17.8 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EER28555.1 - 0.0038 16.6 0.1 0.0084 15.5 0.1 1.5 2 0 0 2 2 2 1 ThiF family KR PF08659.10 EER28555.1 - 0.0062 16.5 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 EER28555.1 - 0.008 16.4 0.0 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.19 EER28555.1 - 0.022 13.8 0.0 0.05 12.6 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.18 EER28555.1 - 0.039 13.8 0.1 0.085 12.7 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EER28555.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DapB_N PF01113.20 EER28555.1 - 0.098 12.8 0.1 0.25 11.5 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus K_oxygenase PF13434.6 EER28555.1 - 0.1 11.7 0.1 0.16 11.1 0.1 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Glyco_trans_4_4 PF13579.6 EER28555.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain GFO_IDH_MocA PF01408.22 EER28555.1 - 0.15 12.9 0.1 0.44 11.4 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Brr6_like_C_C PF10104.9 EER28556.1 - 2e-46 157.1 1.1 2.6e-46 156.7 1.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Neur_chan_memb PF02932.16 EER28556.1 - 0.011 15.9 0.6 5.1 7.1 0.0 2.7 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region AA_permease_2 PF13520.6 EER28557.1 - 5.6e-64 216.5 50.1 6.8e-64 216.3 50.1 1.0 1 0 0 1 1 1 1 Amino acid permease S_4TM PF18159.1 EER28557.1 - 0.17 11.2 0.8 8.1 5.7 0.0 2.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain 2-oxoacid_dh PF00198.23 EER28559.1 - 5.2e-80 268.3 0.1 7.6e-80 267.7 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EER28559.1 - 8.8e-16 57.5 1.0 1.8e-15 56.5 1.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 EER28559.1 - 0.00019 22.1 0.4 0.076 13.7 0.2 2.6 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EER28559.1 - 0.017 14.9 0.1 0.36 10.7 0.1 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like DUF3614 PF12267.8 EER28559.1 - 0.15 12.5 2.4 3 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Presenilin PF01080.17 EER28559.1 - 5.4 5.7 7.6 8.1 5.1 7.6 1.2 1 0 0 1 1 1 0 Presenilin Complex1_LYR PF05347.15 EER28560.1 - 5.1e-10 39.3 0.9 7.3e-10 38.8 0.9 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Histone_H2A_C PF16211.5 EER28561.1 - 1.7e-20 72.5 0.8 3e-20 71.7 0.8 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EER28561.1 - 4.8e-17 62.5 0.0 6.5e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EER28561.1 - 1e-05 25.7 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EER28562.1 - 2.1e-21 76.7 0.7 2.5e-21 76.4 0.7 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EER28562.1 - 4.1e-05 23.8 0.0 0.00011 22.5 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EER28562.1 - 0.00027 21.4 0.0 0.00045 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 EER28562.1 - 0.027 14.1 0.1 0.062 12.9 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Peptidase_C54 PF03416.19 EER28563.1 - 7.8e-95 317.4 0.0 9.4e-95 317.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ntox5 PF15543.6 EER28563.1 - 0.035 13.9 0.1 2.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Bacterial toxin 5 YccV-like PF08755.11 EER28565.1 - 2.1e-30 105.1 0.3 5.7e-30 103.7 0.3 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EER28565.1 - 1.2e-15 57.5 0.0 1.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EER28565.1 - 0.00076 19.3 0.1 0.0046 16.8 0.2 2.3 2 0 0 2 2 2 1 F-box-like US22 PF02393.16 EER28565.1 - 0.07 13.4 0.6 1.3 9.3 0.4 2.9 2 1 0 2 2 2 0 US22 like Peptidase_C12 PF01088.21 EER28566.1 - 2.1e-61 207.4 0.3 7e-61 205.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EER28566.1 - 9.1e-06 25.5 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases HNH_2 PF13391.6 EER28567.1 - 1.2e-10 41.4 0.0 2.5e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease DUF2517 PF10725.9 EER28567.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) ERO1 PF04137.15 EER28568.1 - 3.2e-133 444.3 0.0 4.7e-133 443.8 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Methyltransf_28 PF02636.17 EER28569.1 - 2.8e-36 125.5 0.0 3.4e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2023 PF09633.10 EER28569.1 - 0.071 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2023) Tim17 PF02466.19 EER28570.1 - 8.8e-14 51.8 0.4 1.4e-13 51.2 0.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Brix PF04427.18 EER28571.1 - 2.3e-35 122.5 0.0 3e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain RNase_P_p30 PF01876.16 EER28573.1 - 5e-67 225.5 0.0 6.3e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.25 EER28574.1 - 1.4e-64 218.0 0.0 1.6e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER28574.1 - 5.4e-19 68.5 0.0 7.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER28574.1 - 6.5e-08 32.8 0.1 0.00014 21.8 0.2 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EER28574.1 - 0.0029 16.4 0.0 0.0062 15.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EER28574.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EER28574.1 - 0.035 13.5 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EER28574.1 - 0.075 12.6 0.1 0.075 12.6 0.1 1.9 3 0 0 3 3 3 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 EER28575.1 - 3.7e-217 722.3 0.9 4.4e-216 718.8 0.9 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EER28575.1 - 1.2e-33 116.2 0.8 1.2e-33 116.2 0.8 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EER28575.1 - 1.9e-14 53.2 1.0 7.8e-07 28.2 0.1 4.7 3 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EER28575.1 - 1.2e-07 31.4 5.6 0.00017 21.1 0.0 3.3 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 SIMPL PF04402.14 EER28575.1 - 0.0063 17.0 2.6 0.016 15.7 2.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF541) tRNA-synt_1e PF01406.19 EER28575.1 - 0.021 14.2 0.0 0.49 9.7 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Gpr1_Fun34_YaaH PF01184.19 EER28577.1 - 4.4e-27 95.1 17.1 5.7e-27 94.7 17.1 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-rbx1 PF12678.7 EER28578.1 - 4.2e-08 33.3 5.7 1.5e-07 31.6 5.7 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EER28578.1 - 4.5e-08 33.3 2.7 4.5e-08 33.3 2.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EER28578.1 - 1.5e-07 31.2 0.5 3.3e-07 30.1 0.5 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER28578.1 - 1.3e-05 24.9 6.0 3.4e-05 23.6 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER28578.1 - 1.7e-05 24.8 1.8 4.1e-05 23.5 1.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EER28578.1 - 9.6e-05 22.2 3.6 9.6e-05 22.2 3.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EER28578.1 - 0.00028 20.4 0.8 0.00068 19.2 0.8 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EER28578.1 - 0.0011 18.8 4.1 0.011 15.6 4.7 2.1 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EER28578.1 - 0.002 17.9 0.9 0.002 17.9 0.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EER28578.1 - 0.028 14.1 0.8 0.69 9.7 0.1 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EER28578.1 - 0.035 14.2 5.7 0.51 10.4 5.7 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EER28578.1 - 0.055 13.6 0.9 0.12 12.5 0.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EER28578.1 - 0.69 10.3 2.1 1.4 9.3 2.1 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EER28578.1 - 2.3 8.1 4.2 0.92 9.3 1.3 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ATP_transf PF09830.9 EER28580.1 - 4.2e-23 81.3 0.0 6.9e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 EER28580.1 - 0.031 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) GalP_UDP_transf PF01087.22 EER28580.1 - 0.094 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain zf-C2H2 PF00096.26 EER28581.1 - 0.0069 16.8 23.5 1.2 9.7 1.6 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.7 EER28581.1 - 0.3 11.5 1.4 22 5.6 0.5 3.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-TAZ PF02135.16 EER28581.1 - 0.53 10.8 5.5 0.59 10.6 0.9 2.4 2 0 0 2 2 2 0 TAZ zinc finger zf-C2H2_4 PF13894.6 EER28581.1 - 1.1 10.3 25.0 0.61 11.1 1.1 5.3 5 1 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EER28581.1 - 4.3 7.5 6.1 4.7 7.3 1.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER28581.1 - 5.6 7.4 6.1 42 4.6 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Peroxin-13_N PF04088.13 EER28582.1 - 3.9e-55 186.1 1.2 5.8e-55 185.6 1.2 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EER28582.1 - 3.2e-07 29.9 0.0 6.3e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EER28582.1 - 1.2e-06 28.0 0.0 2.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER28582.1 - 4.1e-06 26.6 0.1 6.7e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_S8 PF00082.22 EER28583.1 - 0.0011 18.3 0.2 0.0012 18.2 0.2 1.0 1 0 0 1 1 1 1 Subtilase family Ureidogly_lyase PF04115.12 EER28584.1 - 4e-57 193.0 0.0 5.2e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase MutS_V PF00488.21 EER28585.1 - 7.4e-75 251.1 0.1 1.3e-74 250.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EER28585.1 - 3.7e-43 148.0 10.0 3.2e-42 144.9 10.0 2.3 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EER28585.1 - 6.8e-21 74.6 0.0 2e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EER28585.1 - 3.3e-08 33.9 0.0 1.2e-07 32.0 0.0 1.9 1 1 0 1 1 1 1 MutS domain II DUF3405 PF11885.8 EER28585.1 - 0.0074 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) AAA_29 PF13555.6 EER28585.1 - 0.071 12.9 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain APG6_N PF17675.1 EER28585.1 - 0.094 13.2 7.4 0.28 11.7 7.4 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region MitMem_reg PF13012.6 EER28585.1 - 0.096 13.1 0.8 5.8 7.4 0.0 3.5 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function AAA_23 PF13476.6 EER28585.1 - 0.51 10.8 0.0 0.51 10.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EER28585.1 - 0.77 10.1 7.5 8.7 6.7 0.1 3.8 2 1 1 3 3 3 0 AAA ATPase domain Sec63 PF02889.16 EER28586.1 - 1e-164 545.9 0.0 4.6e-91 304.5 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EER28586.1 - 1e-49 168.7 0.0 4.7e-28 98.1 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EER28586.1 - 5.3e-29 100.6 0.6 1.7e-28 99.0 0.6 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EER28586.1 - 9.8e-23 81.0 0.0 2.7e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EER28586.1 - 1.6e-12 47.8 0.0 9.4e-08 32.4 0.0 3.5 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EER28586.1 - 8.4e-07 29.3 0.9 0.0034 17.6 0.0 4.3 3 1 0 3 3 3 2 AAA domain T2SSE PF00437.20 EER28586.1 - 0.00061 18.9 0.0 0.52 9.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 EER28586.1 - 0.016 14.6 0.0 1 8.7 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.6 EER28586.1 - 0.052 13.9 0.0 5.8 7.3 0.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.6 EER28586.1 - 0.13 12.6 0.1 11 6.3 0.0 3.1 2 1 0 2 2 2 0 AAA domain Peptidase_S9 PF00326.21 EER28587.1 - 3.6e-50 170.4 0.1 1.2e-49 168.7 0.2 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 EER28587.1 - 0.00047 18.9 0.0 0.077 11.7 0.0 2.1 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EER28587.1 - 0.0033 17.1 1.4 0.0093 15.6 0.1 2.3 2 1 1 3 3 3 1 alpha/beta hydrolase fold Esterase PF00756.20 EER28587.1 - 0.022 14.4 0.1 0.077 12.6 0.1 1.8 1 1 0 1 1 1 0 Putative esterase DUF3189 PF11385.8 EER28587.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) Pkinase PF00069.25 EER28588.1 - 7.4e-25 87.8 0.0 2.5e-14 53.3 0.0 2.9 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER28588.1 - 2.4e-12 46.7 0.1 2.9e-07 30.0 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.25 EER28589.1 - 2.6e-14 53.0 1.8 5.9e-14 51.8 1.8 1.6 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EER28589.1 - 1.1e-06 28.3 11.1 4.8e-05 23.1 0.9 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle DUF1664 PF07889.12 EER28589.1 - 0.0059 16.6 13.4 0.08 13.0 2.1 3.7 3 1 1 4 4 4 1 Protein of unknown function (DUF1664) Peptidase_S46 PF10459.9 EER28589.1 - 0.018 13.7 14.4 0.026 13.2 14.4 1.1 1 0 0 1 1 1 0 Peptidase S46 Fez1 PF06818.15 EER28589.1 - 0.22 11.9 30.4 0.1 13.1 14.9 3.1 2 2 1 3 3 3 0 Fez1 NPV_P10 PF05531.12 EER28589.1 - 0.32 11.5 6.4 30 5.2 0.3 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein C1_2 PF03107.16 EER28589.1 - 0.76 10.1 4.9 5.5 7.4 0.5 2.5 2 0 0 2 2 2 0 C1 domain FliS PF02561.14 EER28589.1 - 0.78 10.0 4.1 0.39 11.0 0.3 2.3 2 0 0 2 2 2 0 Flagellar protein FliS PKcGMP_CC PF16808.5 EER28589.1 - 0.87 9.5 28.7 0.94 9.4 0.6 5.2 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ATG16 PF08614.11 EER28589.1 - 1.1 9.4 40.3 0.018 15.3 5.4 3.9 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EER28589.1 - 1.5 7.4 19.5 0.87 8.2 12.8 2.3 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 EER28589.1 - 2.2 7.1 31.4 0.06 12.2 13.2 3.0 1 1 3 4 4 4 0 Spc7 kinetochore protein PP2C_C PF07830.13 EER28589.1 - 2.5 8.6 4.1 6.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF641 PF04859.12 EER28589.1 - 2.6 8.4 23.2 2.7 8.3 1.3 4.3 1 1 3 4 4 4 0 Plant protein of unknown function (DUF641) BLOC1_2 PF10046.9 EER28589.1 - 2.6 8.4 16.7 0.22 11.8 2.1 4.0 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.12 EER28589.1 - 3.6 7.6 11.6 9.9 6.2 2.4 3.1 1 1 3 4 4 4 0 Laminin Domain II DUF4407 PF14362.6 EER28589.1 - 4 6.7 22.5 3 7.1 2.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EzrA PF06160.12 EER28589.1 - 4.8 5.2 22.7 0.11 10.6 1.3 2.6 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA Spc29 PF17082.5 EER28589.1 - 5.3 6.8 21.2 14 5.5 8.5 3.8 1 1 2 3 3 3 0 Spindle Pole Component 29 FlaC_arch PF05377.11 EER28589.1 - 6.4 7.3 9.8 46 4.5 0.1 3.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) DUF745 PF05335.13 EER28589.1 - 6.6 6.4 15.0 0.092 12.5 4.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.12 EER28589.1 - 7.9 6.5 33.9 0.25 11.4 13.1 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein 3-HAO PF06052.12 EER28590.1 - 6.6e-52 175.2 0.0 9.1e-52 174.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EER28590.1 - 0.00046 19.8 0.0 0.00098 18.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EER28590.1 - 0.0054 16.6 0.4 0.016 15.2 0.1 1.8 2 0 0 2 2 2 1 AraC-like ligand binding domain Zn-ribbon_8 PF09723.10 EER28590.1 - 0.02 15.0 0.6 0.02 15.0 0.6 2.4 3 0 0 3 3 3 0 Zinc ribbon domain Cupin_1 PF00190.22 EER28590.1 - 0.077 12.6 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Cupin C1_2 PF03107.16 EER28590.1 - 0.2 12.0 1.4 10 6.5 0.1 2.4 2 0 0 2 2 2 0 C1 domain zf-RRN7 PF11781.8 EER28590.1 - 3.5 7.4 7.3 0.9 9.3 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 RTC_insert PF05189.13 EER28591.1 - 4e-31 107.6 0.0 7.6e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EER28591.1 - 8.7e-26 90.5 0.1 1.1e-25 90.2 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PWWP PF00855.17 EER28592.1 - 1.1e-16 61.0 1.3 7.8e-16 58.3 1.3 2.5 1 1 0 1 1 1 1 PWWP domain PAP2_3 PF14378.6 EER28593.1 - 3.5e-33 114.9 19.2 8e-17 61.5 0.4 3.4 3 0 0 3 3 3 3 PAP2 superfamily Nse5 PF08691.10 EER28593.1 - 0.044 12.5 0.1 0.071 11.8 0.1 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 PAP2 PF01569.21 EER28593.1 - 1.5 8.6 11.0 0.2 11.4 4.1 2.6 2 1 0 2 2 2 0 PAP2 superfamily DUF2063 PF09836.9 EER28594.1 - 0.067 13.4 0.3 0.3 11.4 0.1 2.1 2 1 1 3 3 3 0 Putative DNA-binding domain Pro-kuma_activ PF09286.11 EER28595.1 - 1.5e-37 129.1 0.0 3e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EER28595.1 - 3.1e-06 26.7 0.2 5.6e-06 25.8 0.2 1.3 1 0 0 1 1 1 1 Subtilase family ComA PF02679.15 EER28596.1 - 1.7e-64 217.6 0.0 2.2e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Pirin PF02678.16 EER28596.1 - 1.4e-30 105.4 0.1 3.1e-30 104.3 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EER28596.1 - 3.9e-23 81.8 0.0 1.2e-22 80.2 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EER28596.1 - 1.2e-05 24.9 0.7 0.0003 20.5 0.9 2.5 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EER28596.1 - 0.065 12.9 0.1 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) PRKCSH PF07915.13 EER28597.1 - 4.9e-18 65.9 1.2 9.3e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EER28597.1 - 0.0043 16.7 0.0 0.026 14.2 0.0 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein SH3_1 PF00018.28 EER28598.1 - 7.1e-37 124.8 5.7 1.2e-13 50.4 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 EER28598.1 - 5.5e-34 115.8 0.0 9e-34 115.1 0.0 1.3 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 EER28598.1 - 1.5e-31 108.0 7.1 9.4e-12 44.6 0.2 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EER28598.1 - 3e-18 65.2 0.1 7.4e-06 25.6 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_10 PF17902.1 EER28598.1 - 9.4e-06 25.6 0.1 0.046 13.8 0.0 3.6 3 0 0 3 3 3 2 SH3 domain SAM_4 PF18017.1 EER28598.1 - 0.00081 19.3 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EER28598.1 - 0.037 14.5 0.0 0.071 13.6 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 EER28598.1 - 0.045 14.0 2.3 0.91 9.8 0.2 3.1 3 0 0 3 3 3 0 Bacterial SH3 domain HSCB_C PF07743.13 EER28600.1 - 1.9e-19 69.9 0.2 2.1e-18 66.6 0.1 2.0 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EER28600.1 - 8.2e-06 25.9 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain 2-Hacid_dh_C PF02826.19 EER28601.1 - 4.2e-55 185.8 0.1 5.7e-55 185.4 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER28601.1 - 1.2e-26 93.0 0.1 1.3e-26 92.8 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EER28601.1 - 1e-06 28.9 0.1 2.4e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EER28601.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EER28601.1 - 0.0025 17.4 0.0 0.0068 16.0 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 EER28601.1 - 0.012 16.1 0.1 0.025 15.0 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding EAP30 PF04157.16 EER28601.1 - 0.034 13.4 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 EAP30/Vps36 family 3HCDH_N PF02737.18 EER28601.1 - 0.059 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EER28601.1 - 0.065 13.8 0.2 0.26 11.9 0.0 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_N PF05222.15 EER28601.1 - 0.079 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain F-box PF00646.33 EER28603.1 - 2.3e-05 24.1 3.5 5.8e-05 22.9 3.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EER28603.1 - 0.00014 21.6 3.0 0.00035 20.4 3.0 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 EER28604.1 - 7.3e-35 118.4 23.1 1.7e-07 31.8 0.2 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat PRP4 PF08799.11 EER28604.1 - 1.6e-13 49.9 2.1 2.9e-13 49.1 2.1 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EER28604.1 - 7.9e-12 45.3 0.0 0.0008 19.7 0.0 4.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nop53 PF07767.11 EER28604.1 - 0.011 15.1 8.8 0.017 14.6 8.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Ribosomal_60s PF00428.19 EER28604.1 - 0.035 14.7 7.2 0.09 13.4 7.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein WD40_like PF17005.5 EER28604.1 - 0.16 11.3 0.0 1.5 8.1 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain DUF2501 PF10696.9 EER28604.1 - 0.17 12.2 0.1 0.38 11.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2501) DUF2052 PF09747.9 EER28604.1 - 0.21 11.7 5.8 0.31 11.1 5.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SpoIIE PF07228.12 EER28605.1 - 2e-11 44.2 0.1 1.1e-10 41.8 0.1 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EER28605.1 - 4.6e-09 36.2 0.3 8.6e-09 35.3 0.3 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 EER28605.1 - 7.4e-05 22.5 0.1 0.052 13.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PMT PF02366.18 EER28606.1 - 2.5e-84 282.7 17.7 4e-84 282.0 17.7 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EER28606.1 - 3e-69 232.6 2.8 3e-69 232.6 2.8 2.7 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EER28606.1 - 1.9e-19 70.2 0.9 4.9e-19 68.9 0.3 1.8 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.6 EER28606.1 - 0.21 11.8 14.1 0.02 15.1 5.8 3.3 3 1 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase MFS_1 PF07690.16 EER28608.1 - 2.4e-27 95.8 30.8 4e-27 95.1 30.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TraL PF07178.11 EER28608.1 - 2 8.9 6.6 3.8 8.1 0.1 3.9 2 1 0 3 3 3 0 TraL protein WD40 PF00400.32 EER28609.1 - 1.8e-05 25.4 12.6 3.7 8.6 0.0 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat PRIMA1 PF16101.5 EER28609.1 - 0.53 10.3 2.4 1.2 9.1 2.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Kri1 PF05178.12 EER28609.1 - 1.1 9.9 6.1 4.4 7.9 0.7 2.5 2 1 0 2 2 2 0 KRI1-like family CSN8_PSD8_EIF3K PF10075.9 EER28610.1 - 3e-24 85.7 0.0 4.6e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family STT3 PF02516.14 EER28611.1 - 1.4e-143 479.4 37.0 2.1e-138 462.3 35.0 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.9 EER28611.1 - 1.2 7.3 9.8 8.8 4.4 9.7 2.1 1 1 0 1 1 1 0 Q-cell neuroblast polarisation DUF3453 PF11935.8 EER28612.1 - 5.1e-77 258.5 1.1 9.4e-77 257.7 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Sds3 PF08598.11 EER28613.1 - 5.4e-18 65.8 6.6 5.4e-18 65.8 6.6 3.2 2 1 1 3 3 3 1 Sds3-like RRM_1 PF00076.22 EER28614.1 - 5.4e-14 51.8 0.1 6.8e-09 35.4 0.0 3.6 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPI-anchored PF10342.9 EER28615.1 - 2.3e-20 73.2 0.3 2.3e-20 73.2 0.3 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NUFIP1 PF10453.9 EER28616.1 - 1.4e-08 34.5 14.6 5.3e-08 32.6 13.2 2.6 1 1 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 EER28616.1 - 1.1e-06 28.4 1.7 1.8e-06 27.7 1.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EER28616.1 - 1.1e-05 25.3 4.8 1.9e-05 24.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EER28616.1 - 0.00017 21.3 3.1 0.00027 20.6 3.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 EER28616.1 - 0.0043 17.7 2.3 0.0057 17.3 0.0 2.3 2 0 0 2 2 2 1 Torus domain RNA_pol_Rbc25 PF08292.12 EER28617.1 - 8e-37 126.4 0.4 2.8e-36 124.6 0.4 1.7 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.23 EER28617.1 - 0.003 17.9 0.0 0.0085 16.4 0.0 1.7 1 1 0 1 1 1 1 S1 RNA binding domain Cys_Met_Meta_PP PF01053.20 EER28618.1 - 2e-141 471.0 0.0 2.3e-141 470.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EER28618.1 - 1e-07 31.5 0.1 1.6e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EER28618.1 - 3.1e-06 26.8 0.2 5.5e-06 25.9 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EER28618.1 - 9.4e-05 21.5 0.4 0.00015 20.8 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EER28618.1 - 0.0053 16.1 0.1 0.011 15.0 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Spc7 PF08317.11 EER28621.1 - 2.2e-06 26.8 35.5 2.2e-06 26.8 35.5 6.7 3 1 3 6 6 6 4 Spc7 kinetochore protein Filament PF00038.21 EER28621.1 - 0.00087 19.0 52.1 0.00087 19.0 52.1 4.5 3 1 3 6 6 6 4 Intermediate filament protein zf-C2H2 PF00096.26 EER28622.1 - 0.00015 22.0 21.1 0.2 12.2 0.4 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER28622.1 - 9.8 7.3 21.9 0.16 12.8 0.7 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EER28623.1 - 3.6e-08 33.4 32.0 0.0063 16.9 0.2 6.7 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EER28623.1 - 0.00021 20.9 20.1 0.08 12.7 4.2 4.6 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 EER28623.1 - 0.00073 20.2 34.2 0.33 11.9 3.3 7.2 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER28623.1 - 0.013 15.8 5.9 0.4 11.0 0.2 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER28623.1 - 0.31 11.5 4.0 8.2 7.0 0.0 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EER28623.1 - 5.2 7.2 8.3 4.1 7.5 0.3 3.0 2 1 1 3 3 3 0 Aberrant zinc-finger Carb_kinase PF01256.17 EER28624.1 - 8.7e-48 162.9 0.0 1.8e-45 155.3 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate kinase PTCB-BRCT PF12738.7 EER28624.1 - 0.14 12.1 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 twin BRCT domain SPT2 PF08243.11 EER28625.1 - 7.3e-10 39.4 14.9 1.4e-09 38.4 14.9 1.4 1 0 0 1 1 1 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 EER28626.1 - 1e-26 93.3 11.1 1.3e-26 93.0 11.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 EER28626.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain Ribosomal_S19 PF00203.21 EER28627.1 - 4.3e-34 116.2 0.4 6e-34 115.8 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SET PF00856.28 EER28629.1 - 4.2e-14 53.3 0.0 7.9e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EER28629.1 - 1e-09 38.3 7.6 1e-09 38.3 7.6 2.0 2 0 0 2 2 2 1 MYND finger CPSase_L_D2 PF02786.17 EER28630.1 - 8.5e-107 355.4 0.0 4.7e-83 277.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EER28630.1 - 3.2e-41 140.5 0.0 9.9e-41 138.9 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EER28630.1 - 6.2e-19 68.2 0.0 1.2e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EER28630.1 - 3.7e-16 59.3 0.4 4.3e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EER28630.1 - 2e-12 47.0 0.0 6e-05 22.8 0.0 3.5 3 1 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EER28630.1 - 1.5e-05 24.6 0.2 0.0067 15.9 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain ATP-grasp_3 PF02655.14 EER28630.1 - 4e-05 23.7 0.0 0.073 13.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.19 EER28630.1 - 9.3e-05 22.3 0.1 0.059 13.1 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RsbRD_N PF14361.6 EER28631.1 - 0.12 13.1 2.7 1.6 9.5 0.2 3.4 3 1 1 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain APH PF01636.23 EER28632.1 - 5.3e-05 23.3 0.0 0.00016 21.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4187 PF13821.6 EER28634.1 - 3.8e-22 77.8 1.6 9.7e-22 76.5 1.6 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EER28634.1 - 1.3e-09 37.8 0.2 5.6e-09 35.7 0.2 2.1 1 1 0 1 1 1 1 G-patch domain PALP PF00291.25 EER28635.1 - 9.9e-41 140.1 0.1 1.2e-40 139.8 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme COesterase PF00135.28 EER28636.1 - 2.6e-83 280.7 0.0 3.4e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EER28636.1 - 5.6e-06 26.4 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EER28636.1 - 4.3e-05 23.1 0.0 6.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EER28636.1 - 0.0042 17.7 0.0 0.0079 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EER28636.1 - 0.097 11.6 0.0 0.27 10.1 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF2974 PF11187.8 EER28636.1 - 0.11 12.0 0.1 0.59 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) TPR_12 PF13424.6 EER28637.1 - 1.5e-58 195.0 34.1 2.3e-16 59.8 0.0 6.2 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 EER28637.1 - 1.3e-48 161.6 21.0 1.4e-07 31.2 0.2 8.8 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 EER28637.1 - 7.7e-18 63.1 18.9 0.019 15.0 0.9 9.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_MalT PF17874.1 EER28637.1 - 2.1e-17 63.5 16.1 1.2e-11 44.6 5.2 2.7 1 1 2 3 3 3 3 MalT-like TPR region TPR_1 PF00515.28 EER28637.1 - 1.8e-16 59.1 22.0 0.00098 18.9 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 EER28637.1 - 2.4e-16 58.5 16.7 0.11 12.8 0.3 8.8 8 0 0 8 8 8 4 Tetratricopeptide repeat NB-ARC PF00931.22 EER28637.1 - 1.4e-14 53.9 0.0 2.6e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.6 EER28637.1 - 3.5e-10 39.2 18.6 0.069 13.2 0.0 8.6 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EER28637.1 - 2.7e-09 37.1 22.5 0.93 10.5 0.4 8.8 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EER28637.1 - 4.8e-09 36.7 17.8 0.0093 16.6 2.3 7.0 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EER28637.1 - 1.2e-07 32.1 21.1 0.57 10.7 2.5 6.9 4 1 3 7 7 7 2 Tetratricopeptide repeat AAA_16 PF13191.6 EER28637.1 - 2e-07 31.6 0.2 7.3e-07 29.7 0.2 2.1 1 0 0 1 1 1 1 AAA ATPase domain Patatin PF01734.22 EER28637.1 - 3.4e-07 30.6 0.9 2.1e-06 28.1 0.1 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase TPR_4 PF07721.14 EER28637.1 - 1.1e-06 28.7 12.9 2.5 9.0 0.1 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 EER28637.1 - 0.00036 20.5 0.2 0.15 12.1 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat 14-3-3 PF00244.20 EER28637.1 - 0.00053 19.5 2.4 0.023 14.2 0.0 2.7 3 0 0 3 3 3 1 14-3-3 protein ATPase_2 PF01637.18 EER28637.1 - 0.0012 18.8 0.0 0.003 17.5 0.0 1.7 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TPR_17 PF13431.6 EER28637.1 - 0.0042 17.4 10.5 9.9 6.8 0.0 7.1 7 1 0 7 7 7 0 Tetratricopeptide repeat NAGLU PF05089.12 EER28637.1 - 0.012 14.6 1.2 4.8 6.0 0.1 3.4 3 1 1 4 4 4 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain IstB_IS21 PF01695.17 EER28637.1 - 0.022 14.5 0.0 0.071 12.8 0.0 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein RPN6_N PF18055.1 EER28637.1 - 0.033 14.6 9.6 1.1 9.7 0.7 3.9 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain TniB PF05621.11 EER28637.1 - 0.051 13.0 0.1 0.29 10.5 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 EER28637.1 - 0.055 13.5 0.0 0.21 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EER28637.1 - 0.093 12.7 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF1897 PF09005.10 EER28637.1 - 1.5 8.4 6.9 32 4.1 0.3 4.6 5 0 0 5 5 5 0 Domain of unknown function (DUF1897) Pkinase PF00069.25 EER28638.1 - 1.6e-10 40.8 0.0 2.6e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER28638.1 - 0.0029 16.9 0.1 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Fungal_trans PF04082.18 EER28639.1 - 4.1e-08 32.6 3.6 5.1e-08 32.3 1.1 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28639.1 - 6.4e-08 32.6 12.7 1.4e-07 31.5 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop14 PF04147.12 EER28640.1 - 3.3e-296 985.2 20.6 3.9e-296 984.9 20.6 1.1 1 0 0 1 1 1 1 Nop14-like family HEAT_2 PF13646.6 EER28641.1 - 0.0006 20.2 3.3 0.00066 20.0 1.2 2.2 2 0 0 2 2 2 1 HEAT repeats ORC_WH_C PF18137.1 EER28642.1 - 7.5e-26 90.9 0.2 8.8e-14 51.8 0.0 2.3 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 EER28643.1 - 2.3e-17 63.1 0.0 5e-12 45.6 0.0 2.1 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 3 N-terminus PPR_2 PF13041.6 EER28644.1 - 5.2e-05 23.4 2.2 1.2 9.4 0.0 5.1 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.6 EER28644.1 - 0.0008 19.4 0.2 13 5.9 0.0 3.6 3 0 0 3 3 3 1 Pentatricopeptide repeat domain Glyco_transf_64 PF09258.10 EER28644.1 - 0.0059 15.9 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain PPR PF01535.20 EER28644.1 - 0.1 12.9 0.1 7.9 7.0 0.0 3.4 3 0 0 3 3 3 0 PPR repeat Rap1_C PF11626.8 EER28644.1 - 0.12 12.4 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain TPR_14 PF13428.6 EER28644.1 - 0.19 12.6 1.8 36 5.5 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat LprI PF07007.12 EER28644.1 - 1.1 9.9 3.8 3.1 8.5 0.1 2.6 2 0 0 2 2 2 0 Lysozyme inhibitor LprI FapA PF03961.13 EER28644.1 - 1.7 7.1 3.3 2.5 6.6 3.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sec66 PF09802.9 EER28645.1 - 2.8e-83 277.9 0.2 3.4e-83 277.6 0.2 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 rRNA_processing PF08524.11 EER28645.1 - 0.012 15.7 0.1 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 rRNA processing DUF3848 PF12959.7 EER28645.1 - 0.034 14.2 0.0 0.088 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Duffy_binding PF05424.11 EER28645.1 - 0.22 11.6 3.1 0.33 11.0 3.1 1.4 1 1 0 1 1 1 0 Duffy binding domain AAA PF00004.29 EER28646.1 - 3.2e-51 173.2 0.0 2.5e-42 144.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER28646.1 - 1.3e-10 40.9 0.0 6.4e-10 38.7 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EER28646.1 - 3.4e-08 34.1 0.1 2.3e-05 24.8 0.0 3.8 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 EER28646.1 - 1.7e-07 31.2 0.0 3.3e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EER28646.1 - 5.7e-06 26.6 0.0 1.9e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Bromodomain PF00439.25 EER28646.1 - 0.0002 21.4 0.0 0.00048 20.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain AAA_5 PF07728.14 EER28646.1 - 0.0003 20.8 0.0 0.0019 18.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EER28646.1 - 0.00098 18.9 0.0 0.089 12.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EER28646.1 - 0.0019 18.6 0.0 0.0051 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EER28646.1 - 0.002 18.3 0.0 0.043 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EER28646.1 - 0.002 18.2 0.0 1.8 8.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 EER28646.1 - 0.0026 17.4 0.0 0.0096 15.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EER28646.1 - 0.0042 17.1 0.0 0.025 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EER28646.1 - 0.0049 17.1 1.3 0.076 13.3 0.3 3.1 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 EER28646.1 - 0.0075 15.5 0.0 0.024 13.8 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 EER28646.1 - 0.0083 16.0 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EER28646.1 - 0.015 15.1 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EER28646.1 - 0.015 14.7 0.0 0.084 12.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EER28646.1 - 0.03 14.0 0.0 1.9 8.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.27 EER28646.1 - 0.04 14.4 1.7 0.15 12.6 0.0 2.9 3 0 0 3 3 1 0 ABC transporter AAA_18 PF13238.6 EER28646.1 - 0.056 14.0 0.0 0.29 11.7 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EER28646.1 - 0.073 12.9 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EER28646.1 - 0.094 11.8 0.0 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EER28646.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EER28646.1 - 0.32 11.2 0.0 0.32 11.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain TFIIF_alpha PF05793.12 EER28646.1 - 8.9 4.8 60.6 1.7 7.1 26.9 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CPSF_A PF03178.15 EER28647.1 - 3.9e-112 374.7 0.0 7.2e-112 373.9 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region LMBR1 PF04791.16 EER28648.1 - 5.3e-13 48.7 23.3 2.9e-10 39.7 10.5 2.4 2 1 0 3 3 3 2 LMBR1-like membrane protein DUF3611 PF12263.8 EER28648.1 - 0.049 13.5 6.3 0.054 13.4 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Gaa1 PF04114.14 EER28648.1 - 0.65 8.9 9.6 0.12 11.4 2.0 2.2 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component HemY_N PF07219.13 EER28648.1 - 1.6 9.0 0.0 1.6 9.0 0.0 4.4 5 1 1 6 6 6 0 HemY protein N-terminus DUF3671 PF12420.8 EER28648.1 - 3.6 7.7 9.2 1.4 9.0 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function zf-FPG_IleRS PF06827.14 EER28649.1 - 0.046 13.6 1.2 6.5 6.7 0.6 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS CEBP_ZZ PF16366.5 EER28649.1 - 0.18 12.0 6.4 0.13 12.5 4.2 1.8 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain cwf21 PF08312.12 EER28649.1 - 9 6.5 7.2 12 6.2 1.8 3.2 2 1 0 2 2 2 0 cwf21 domain SLATT_1 PF18181.1 EER28650.1 - 0.044 13.7 0.2 0.073 13.0 0.2 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 SDP_N PF12278.8 EER28650.1 - 2.2 8.4 6.4 1.9 8.6 2.5 2.1 2 0 0 2 2 2 0 Sex determination protein N terminal Sox_N PF12444.8 EER28650.1 - 5.1 8.3 6.8 2.5 9.3 4.1 1.8 2 0 0 2 2 2 0 Sox developmental protein N terminal Atg14 PF10186.9 EER28651.1 - 3.2e-99 332.0 0.0 4.1e-99 331.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Dynamitin PF04912.14 EER28651.1 - 0.0085 15.5 2.3 0.012 15.0 2.3 1.1 1 0 0 1 1 1 1 Dynamitin HIP1_clath_bdg PF16515.5 EER28651.1 - 0.018 15.7 3.5 0.018 15.7 3.5 2.0 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 EER28651.1 - 0.071 12.0 7.4 0.11 11.4 7.4 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EER28651.1 - 0.077 12.5 2.9 0.1 12.1 2.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit FAM76 PF16046.5 EER28651.1 - 0.19 11.0 5.0 0.29 10.4 5.0 1.2 1 0 0 1 1 1 0 FAM76 protein DUF2401 PF10287.9 EER28652.1 - 4.1e-91 304.7 0.0 6.4e-91 304.0 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EER28652.1 - 1.7e-25 89.2 0.0 4.3e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) APH PF01636.23 EER28653.1 - 0.058 13.3 0.0 0.076 12.9 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zip PF02535.22 EER28654.1 - 2.4e-52 178.2 1.0 4.8e-52 177.3 1.0 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter Thiolase_N PF00108.23 EER28655.1 - 8.4e-92 307.2 0.0 1.3e-91 306.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EER28655.1 - 4.4e-44 149.1 1.0 1.1e-43 147.8 1.0 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EER28655.1 - 8.5e-06 25.5 0.2 1.9e-05 24.3 0.2 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EER28655.1 - 0.0082 16.0 0.5 1.3 8.9 0.0 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 EER28656.1 - 3.7e-46 157.1 0.0 5.4e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EER28656.1 - 3.9e-28 98.5 5.4 6.9e-28 97.7 5.4 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EER28656.1 - 4.2e-23 81.4 0.0 1.1e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EER28656.1 - 1e-19 70.4 0.0 2.5e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EER28656.1 - 2e-10 40.9 0.0 4.8e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EER28656.1 - 3.4e-07 30.2 0.1 9.7e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EER28656.1 - 3.5e-06 27.1 0.1 6.5e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EER28656.1 - 0.16 11.6 0.1 0.59 9.7 0.0 1.9 2 0 0 2 2 2 0 Ras family Septin PF00735.18 EER28656.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Septin FeS_assembly_P PF01883.19 EER28657.1 - 1.2e-09 38.2 0.0 2.6e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Fungal_trans PF04082.18 EER28658.1 - 8.2e-14 51.3 0.1 1.7e-13 50.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28658.1 - 0.00028 20.9 8.4 0.00028 20.9 8.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC_CDC26 PF10471.9 EER28659.1 - 6e-19 68.7 1.4 8.1e-19 68.2 1.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 RRF PF01765.19 EER28661.1 - 1.7e-43 148.4 2.9 2.2e-43 148.0 2.9 1.1 1 0 0 1 1 1 1 Ribosome recycling factor DUF1664 PF07889.12 EER28661.1 - 1.1 9.2 3.2 4.1 7.5 2.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ISET-FN3_linker PF16625.5 EER28661.1 - 1.6 9.4 5.3 1.3 9.6 3.0 2.1 2 1 0 2 2 2 0 Unstructured linking region I-set and fnIII on Brother of CDO HSP70 PF00012.20 EER28662.1 - 6.4e-228 757.8 8.3 7.2e-228 757.6 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EER28662.1 - 3.6e-16 58.9 0.1 3e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EER28662.1 - 0.00043 20.1 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Bromodomain PF00439.25 EER28663.1 - 1.5e-30 105.1 2.4 1.1e-16 60.7 0.1 2.7 3 0 0 3 3 3 2 Bromodomain CKS PF01111.19 EER28664.1 - 6.2e-32 109.7 1.1 6.2e-32 109.7 1.1 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.6 EER28665.1 - 2.7e-07 30.9 0.0 1.5e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EER28665.1 - 0.28 10.9 3.5 0.61 9.8 0.7 2.4 2 1 1 3 3 3 0 DSBA-like thioredoxin domain TPPK_C PF12555.8 EER28666.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF3844 PF12955.7 EER28667.1 - 7.2e-37 125.7 2.4 1.1e-36 125.2 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_alliinase PF04863.13 EER28667.1 - 0.82 10.1 6.0 2.1 8.8 6.0 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain DUF2374 PF09574.10 EER28667.1 - 3.9 7.4 5.7 0.52 10.2 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) zf-RING_2 PF13639.6 EER28668.1 - 3.6e-13 49.6 5.8 5.4e-13 49.1 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EER28668.1 - 7.7e-09 35.1 0.7 1.4e-08 34.3 0.7 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EER28668.1 - 1.4e-08 34.4 5.3 2.3e-08 33.7 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER28668.1 - 5.3e-08 32.6 3.0 8.4e-08 32.0 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER28668.1 - 1.8e-06 27.8 3.0 2.9e-06 27.1 3.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EER28668.1 - 6.4e-06 26.4 10.4 3.3e-05 24.1 10.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EER28668.1 - 9.2e-05 22.4 0.8 9.2e-05 22.4 0.8 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EER28668.1 - 0.0007 19.4 2.0 0.0012 18.7 2.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EER28668.1 - 0.0014 18.6 2.4 0.0033 17.4 2.4 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EER28668.1 - 0.025 14.2 3.7 0.048 13.3 3.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EER28668.1 - 0.039 13.7 6.0 0.068 13.0 6.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EER28668.1 - 0.041 14.0 3.1 0.086 13.0 3.1 1.6 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 EER28668.1 - 0.046 13.6 5.3 0.089 12.7 5.3 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 EER28668.1 - 0.064 13.1 4.6 0.14 12.0 4.6 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EER28668.1 - 0.11 12.6 3.8 0.32 11.2 3.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain OAD_gamma PF04277.13 EER28668.1 - 0.17 12.5 0.1 0.76 10.4 0.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_4 PF15227.6 EER28668.1 - 0.47 10.7 4.4 1.1 9.5 4.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 EER28668.1 - 2.7 8.0 7.9 0.12 12.4 1.0 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 p450 PF00067.22 EER28669.1 - 1.6e-47 162.3 0.0 2e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arena_RNA_pol PF06317.11 EER28669.1 - 0.14 9.3 0.0 0.19 8.9 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase MFS_1 PF07690.16 EER28670.1 - 5.8e-31 107.7 30.1 5.8e-31 107.7 30.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4234 PF14018.6 EER28670.1 - 0.28 11.4 2.0 1.3 9.1 2.0 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) DUF1461 PF07314.11 EER28670.1 - 1.6 8.6 4.7 0.55 10.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1461) Egh16-like PF11327.8 EER28671.1 - 2.3e-59 200.9 8.6 4.6e-59 199.9 8.6 1.5 1 0 0 1 1 1 1 Egh16-like virulence factor Pro_isomerase PF00160.21 EER28672.1 - 3.1e-49 167.3 0.2 3.6e-49 167.1 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD INTS5_C PF14838.6 EER28673.1 - 0.068 11.8 0.0 0.084 11.5 0.0 1.0 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus tRNA-synt_2c PF01411.19 EER28674.1 - 2.3e-218 726.2 0.0 3.2e-218 725.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EER28674.1 - 7.1e-17 61.2 0.8 1.8e-16 60.0 0.8 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EER28674.1 - 1.5e-10 41.6 2.3 4.3e-10 40.1 2.3 1.8 1 0 0 1 1 1 1 DHHA1 domain SH3BGR PF04908.15 EER28674.1 - 0.083 13.1 0.1 0.25 11.5 0.1 1.8 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF3752 PF12572.8 EER28675.1 - 6.3e-43 146.9 10.2 6.3e-43 146.9 10.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) APH PF01636.23 EER28676.1 - 3.3e-12 46.8 0.9 4.6e-11 43.1 0.0 3.1 3 1 0 3 3 3 1 Phosphotransferase enzyme family Peptidase_S10 PF00450.22 EER28677.1 - 2e-81 274.6 0.0 2.5e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase A_deaminase PF00962.22 EER28683.1 - 2.3e-123 411.7 0.0 3.1e-123 411.3 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase F-box PF00646.33 EER28684.1 - 0.0024 17.7 0.0 0.0074 16.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EER28684.1 - 0.0025 17.6 0.4 0.006 16.4 0.0 1.8 2 0 0 2 2 2 1 F-box-like NdhS PF11623.8 EER28684.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S SH3_9 PF14604.6 EER28685.1 - 3e-29 100.6 4.9 2.8e-14 52.7 0.3 2.9 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EER28685.1 - 1.8e-25 88.3 3.5 1.5e-12 46.9 0.3 2.5 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 EER28685.1 - 4.6e-15 55.5 0.0 8.9e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 EER28685.1 - 1.6e-14 53.3 0.1 6.8e-08 32.1 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain Dynamin_M PF01031.20 EER28686.1 - 8e-111 369.8 0.0 1.7e-110 368.8 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EER28686.1 - 3e-57 193.3 0.6 1.2e-56 191.4 0.1 2.2 3 0 0 3 3 3 1 Dynamin family GED PF02212.18 EER28686.1 - 7.7e-32 109.3 1.2 7.7e-32 109.3 1.2 1.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EER28686.1 - 8.6e-05 22.6 0.3 0.0016 18.5 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PBP PF01161.20 EER28687.1 - 2.1e-19 70.2 0.0 3.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF3088 PF11287.8 EER28687.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) UAA PF08449.11 EER28688.1 - 7.4e-84 281.5 14.8 1.4e-81 274.1 14.8 2.0 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EER28688.1 - 0.012 14.8 0.1 0.012 14.8 0.1 1.9 2 0 0 2 2 2 0 Nucleotide-sugar transporter Rad17 PF03215.15 EER28689.1 - 5e-23 82.0 0.0 2.2e-22 79.9 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA PF00004.29 EER28689.1 - 0.0078 16.6 0.0 0.021 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EER28689.1 - 0.012 16.0 0.0 0.047 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EER28689.1 - 0.017 15.6 0.0 0.056 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EER28689.1 - 0.027 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EER28689.1 - 0.038 14.2 0.3 0.26 11.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EER28689.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EER28689.1 - 0.16 11.7 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase ELMO_CED12 PF04727.13 EER28690.1 - 2.9e-53 180.6 0.1 1.2e-52 178.6 0.3 1.9 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 EER28690.1 - 4.1e-36 124.5 6.2 1.2e-34 119.8 4.2 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain DUF3361 PF11841.8 EER28690.1 - 6.1e-18 65.2 0.4 1.5e-17 64.0 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Macoilin PF09726.9 EER28690.1 - 0.55 8.7 6.1 0.76 8.3 6.1 1.2 1 0 0 1 1 1 0 Macoilin family DUF1752 PF08550.10 EER28691.1 - 4.5e-07 29.6 3.0 9e-07 28.6 3.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.16 EER28692.1 - 1.1e-31 110.1 28.3 4.6e-31 108.0 29.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SUI1 PF01253.22 EER28693.1 - 4.3e-25 88.0 0.6 9.4e-25 87.0 0.6 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.6 EER28693.1 - 0.021 14.8 0.4 0.041 13.9 0.4 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Cgr1 PF03879.14 EER28695.1 - 1.2e-33 115.7 33.4 1.3e-33 115.5 33.4 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2868 PF11067.8 EER28695.1 - 1.8 8.0 4.9 2.2 7.7 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) STAT_bind PF02864.15 EER28695.1 - 3.2 8.3 6.3 4.1 8.0 6.3 1.1 1 0 0 1 1 1 0 STAT protein, DNA binding domain Nucleo_P87 PF07267.11 EER28695.1 - 4.6 6.0 11.5 4.9 5.9 11.5 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VIR_N PF15912.5 EER28695.1 - 8 6.0 9.0 10 5.6 9.0 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal RR_TM4-6 PF06459.12 EER28695.1 - 8.9 6.0 14.6 9.4 6.0 14.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mito_carr PF00153.27 EER28696.1 - 1.3e-62 207.8 0.5 3e-21 75.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.23 EER28698.1 - 2e-10 40.5 0.1 4e-10 39.5 0.1 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EER28698.1 - 7.3e-09 35.9 1.4 4.9e-06 26.8 0.3 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EER28698.1 - 0.00073 19.2 0.1 1 8.9 0.0 2.1 2 0 0 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sortilin-Vps10 PF15902.5 EER28699.1 - 1.7e-296 982.9 6.4 2.7e-155 517.5 0.8 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EER28699.1 - 1.2e-98 328.3 13.4 7.3e-52 176.1 5.1 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EER28699.1 - 3.6e-06 26.2 46.2 2.5 8.5 0.0 11.7 12 0 0 12 12 12 4 BNR/Asp-box repeat PSII_BNR PF14870.6 EER28699.1 - 6.5e-05 22.3 5.9 0.11 11.7 0.0 4.9 4 2 1 5 5 5 2 Photosynthesis system II assembly factor YCF48 DUF2167 PF09935.9 EER28699.1 - 0.0033 16.6 0.2 0.026 13.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2167) DUF3344 PF11824.8 EER28699.1 - 0.035 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3344) Mo-co_dimer PF03404.16 EER28699.1 - 0.21 11.6 0.5 62 3.6 0.0 4.1 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain preSET_CXC PF18264.1 EER28699.1 - 4.4 7.9 11.3 2.9 8.4 1.2 2.6 2 0 0 2 2 2 0 CXC domain Polysacc_deac_1 PF01522.21 EER28700.1 - 2.7e-21 75.7 0.0 4.1e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GFRP PF06399.13 EER28700.1 - 0.079 12.9 0.0 2.7 7.9 0.0 3.0 4 0 0 4 4 4 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Methyltransf_24 PF13578.6 EER28700.1 - 0.09 13.8 0.0 0.18 12.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain pPIWI_RE_REase PF18154.1 EER28700.1 - 0.093 12.7 0.0 3.1 7.8 0.0 2.2 2 0 0 2 2 2 0 REase associating with pPIWI_RE Polysacc_deac_2 PF04748.13 EER28700.1 - 0.13 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase adh_short_C2 PF13561.6 EER28703.1 - 6.2e-09 35.8 0.0 2.5e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER28703.1 - 2.8e-08 33.4 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EER28703.1 - 0.0015 18.5 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TFIIS_M PF07500.14 EER28704.1 - 7.3e-31 107.0 1.3 1.8e-30 105.7 0.9 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EER28704.1 - 1.4e-18 66.5 4.7 3.1e-18 65.4 4.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EER28704.1 - 1.6e-13 50.4 0.3 4.2e-13 49.1 0.3 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LPD39 PF18858.1 EER28704.1 - 0.037 14.1 1.9 0.054 13.6 0.2 2.0 2 1 0 2 2 2 0 Large polyvalent protein associated domain 39 Baculo_LEF5_C PF11792.8 EER28704.1 - 0.095 12.4 0.1 0.095 12.4 0.1 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-LITAF-like PF10601.9 EER28704.1 - 0.2 11.9 1.9 0.4 11.0 1.9 1.4 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain Fungal_trans PF04082.18 EER28705.1 - 1.2e-21 77.0 0.1 2.2e-21 76.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28705.1 - 1.3e-07 31.6 13.2 2.4e-07 30.8 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.15 EER28706.1 - 1.4e-31 110.5 0.0 2.2e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EER28706.1 - 5.7e-20 72.0 0.0 1e-19 71.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.11 EER28706.1 - 4.1e-16 59.0 0.0 1.2e-15 57.5 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EER28706.1 - 9.9e-08 31.6 0.4 1.8e-07 30.8 0.4 1.5 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EER28706.1 - 5.7e-07 29.7 0.0 1.6e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_8 PF12780.7 EER28706.1 - 0.14 11.5 0.1 0.34 10.2 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region D4 Caps_synth PF05704.12 EER28708.1 - 0.13 11.7 0.2 0.35 10.2 0.2 1.6 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Sec10 PF07393.11 EER28709.1 - 1.1e-226 754.7 0.0 1.2e-226 754.5 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 LpxC PF03331.13 EER28709.1 - 0.049 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 UDP-3-O-acyl N-acetylglycosamine deacetylase Ank_2 PF12796.7 EER28710.1 - 1.4e-82 272.4 12.2 2.9e-15 56.6 0.0 9.6 4 3 3 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER28710.1 - 9.6e-67 220.6 18.5 7.1e-09 36.0 0.0 13.4 8 4 5 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER28710.1 - 8.1e-60 191.7 23.7 9.9e-06 25.5 0.0 19.4 21 0 0 21 21 21 12 Ankyrin repeat Ank PF00023.30 EER28710.1 - 3.4e-56 185.4 35.4 1.3e-05 25.4 0.0 16.9 17 0 0 17 17 17 12 Ankyrin repeat Ank_5 PF13857.6 EER28710.1 - 1.2e-46 156.1 26.9 8.1e-08 32.4 0.1 13.3 4 3 9 14 14 14 10 Ankyrin repeats (many copies) F-box-like PF12937.7 EER28710.1 - 8e-07 28.9 1.3 2.2e-06 27.4 1.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER28710.1 - 0.022 14.7 0.6 0.048 13.5 0.6 1.6 1 0 0 1 1 1 0 F-box domain MBOAT_2 PF13813.6 EER28711.1 - 2.9e-15 56.3 3.1 5.2e-15 55.5 0.7 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MHYT PF03707.16 EER28711.1 - 0.18 12.0 4.2 1.1 9.5 0.1 3.5 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat LRR_6 PF13516.6 EER28712.1 - 3.8e-07 29.6 7.0 0.19 11.8 0.1 6.6 8 0 0 8 8 8 2 Leucine Rich repeat LRR_4 PF12799.7 EER28712.1 - 0.00045 20.6 9.5 4.9 7.7 0.2 5.6 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) Paf1 PF03985.13 EER28712.1 - 0.13 11.2 20.6 0.19 10.7 20.6 1.1 1 0 0 1 1 1 0 Paf1 NOA36 PF06524.12 EER28712.1 - 0.44 9.8 9.6 0.66 9.2 9.6 1.2 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EER28712.1 - 1.1 8.7 22.3 1.4 8.2 22.3 1.1 1 0 0 1 1 1 0 SDA1 AAA_11 PF13086.6 EER28712.1 - 1.1 9.0 5.4 1.8 8.3 5.4 1.3 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EER28712.1 - 3.7 6.2 3.9 4.9 5.8 3.9 1.1 1 0 0 1 1 1 0 Presenilin GrpE PF01025.19 EER28712.1 - 4.5 6.9 20.0 5.5 6.6 18.5 1.7 1 1 1 2 2 2 0 GrpE DNA_pol_phi PF04931.13 EER28712.1 - 6.6 4.7 25.2 9.2 4.2 25.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi COX17 PF05051.13 EER28713.1 - 6.8e-22 77.6 5.6 8.4e-22 77.3 5.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EER28713.1 - 0.0072 16.3 2.0 0.086 12.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Alg6_Alg8 PF03155.15 EER28714.1 - 3.3e-127 425.4 22.0 8.8e-82 275.6 8.2 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.22 EER28715.1 - 8.1e-40 134.5 0.0 2e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER28715.1 - 2.8e-05 24.2 0.0 0.21 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif SET_assoc PF11767.8 EER28715.1 - 0.14 11.8 0.0 7.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Ribosomal_L37 PF08561.10 EER28717.1 - 1.8e-42 144.6 1.6 2.7e-42 144.1 1.6 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 TMEM154 PF15102.6 EER28718.1 - 0.0019 18.1 0.0 0.0046 16.9 0.0 1.6 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 EER28718.1 - 0.061 13.1 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF1970 PF09301.10 EER28718.1 - 0.67 10.2 3.8 9.8 6.5 0.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1970) Cpn60_TCP1 PF00118.24 EER28719.1 - 8.3e-140 466.7 11.4 1e-139 466.4 11.4 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 EER28720.1 - 1.3e-40 138.9 0.0 2.2e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER28720.1 - 3.2e-05 23.7 0.0 7.8e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EER28720.1 - 0.00011 22.2 0.0 0.00043 20.3 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EER28720.1 - 0.00012 22.3 0.0 0.0063 16.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EER28720.1 - 0.00032 20.8 0.0 0.00083 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EER28720.1 - 0.0005 20.5 0.1 0.012 16.0 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EER28720.1 - 0.0016 17.6 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EER28720.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EER28720.1 - 0.018 15.3 0.1 0.063 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EER28720.1 - 0.05 13.8 0.0 0.094 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EER28720.1 - 0.052 13.0 0.0 0.16 11.4 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EER28720.1 - 0.059 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EER28720.1 - 0.07 12.8 0.1 0.6 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EER28720.1 - 0.087 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EER28720.1 - 0.099 12.4 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EER28720.1 - 0.12 12.9 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EER28720.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.24 EER28721.1 - 9e-125 417.0 2.7 1.1e-124 416.7 2.7 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EER28721.1 - 4e-44 149.7 0.9 6.3e-44 149.1 0.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EER28721.1 - 2.9e-06 26.7 1.2 0.00057 19.2 0.5 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EER28721.1 - 3.3e-05 23.1 1.8 0.02 14.0 2.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EER28721.1 - 4.9e-05 22.7 0.2 0.051 12.8 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EER28721.1 - 0.0037 16.6 1.0 0.0064 15.8 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EER28721.1 - 0.054 13.1 1.7 0.14 11.7 1.7 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EER28721.1 - 0.15 11.0 0.2 1.2 8.1 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.14 EER28721.1 - 0.21 10.3 1.4 0.97 8.1 0.7 2.4 3 0 0 3 3 3 0 HI0933-like protein DPPIV_N PF00930.21 EER28722.1 - 2.3e-112 375.3 0.1 3.2e-112 374.8 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EER28722.1 - 1.6e-56 191.1 2.7 2.9e-56 190.3 2.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EER28722.1 - 1.9e-06 27.7 2.4 0.00035 20.2 1.5 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EER28722.1 - 0.033 13.8 0.3 0.14 11.7 0.2 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 EER28722.1 - 0.051 13.1 0.0 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 EER28722.1 - 0.16 10.5 0.0 9.1 4.7 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PI-PLC-X PF00388.19 EER28723.1 - 4.1e-63 211.3 0.1 6.2e-63 210.7 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EER28723.1 - 1.7e-41 141.2 0.1 4.1e-41 139.9 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain HECT_2 PF09814.9 EER28724.1 - 7.5e-35 120.5 0.0 8.3e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HECT_2 PF09814.9 EER28725.1 - 6.8e-54 183.1 0.2 8.1e-54 182.9 0.2 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Ribosomal_S27e PF01667.17 EER28725.1 - 0.00023 20.8 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 ArsA_HSP20 PF17886.1 EER28725.1 - 0.00042 19.8 0.0 0.00081 18.9 0.0 1.4 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Questin_oxidase PF14027.6 EER28726.1 - 8.3e-87 291.9 2.8 1e-86 291.6 2.8 1.1 1 0 0 1 1 1 1 Questin oxidase-like Imm51 PF15595.6 EER28726.1 - 0.013 15.4 0.1 0.77 9.7 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 51 AAA PF00004.29 EER28727.1 - 1.4e-46 158.1 0.0 3.6e-43 147.2 0.0 3.2 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EER28727.1 - 1.6e-06 27.8 3.8 0.00048 19.9 0.1 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EER28727.1 - 1.2e-05 25.8 0.5 0.022 15.1 0.0 4.0 3 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EER28727.1 - 0.00014 21.7 0.0 0.0004 20.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EER28727.1 - 0.00055 19.1 0.0 0.00091 18.4 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 EER28727.1 - 0.002 18.5 0.0 0.015 15.7 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 EER28727.1 - 0.0031 17.7 0.0 0.0073 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EER28727.1 - 0.0046 17.2 0.0 0.047 14.0 0.0 2.7 2 1 1 3 3 2 1 AAA domain TIP49 PF06068.13 EER28727.1 - 0.0059 15.9 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EER28727.1 - 0.0076 16.0 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EER28727.1 - 0.008 15.8 0.1 0.054 13.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EER28727.1 - 0.01 16.3 0.0 0.1 13.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EER28727.1 - 0.014 15.5 0.0 0.42 10.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EER28727.1 - 0.016 14.6 0.2 0.078 12.3 0.0 2.1 3 0 0 3 3 3 0 KaiC TsaE PF02367.17 EER28727.1 - 0.016 15.2 0.2 0.15 12.0 0.0 2.6 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EER28727.1 - 0.023 14.2 0.0 0.08 12.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EER28727.1 - 0.025 14.0 0.1 0.049 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EER28727.1 - 0.04 13.9 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 EER28727.1 - 0.045 13.8 0.0 0.79 9.8 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain PhoH PF02562.16 EER28727.1 - 0.069 12.6 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EER28727.1 - 0.081 13.2 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EER28727.1 - 0.2 11.4 0.2 0.91 9.2 0.1 2.1 2 0 0 2 2 2 0 AAA domain FAD_binding_4 PF01565.23 EER28728.1 - 5.5e-19 68.3 0.3 1e-18 67.4 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2H2 PF00096.26 EER28729.1 - 0.0057 17.1 5.9 0.0057 17.1 5.9 2.9 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER28729.1 - 0.014 16.1 4.7 0.014 16.1 4.7 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger FAD_binding_3 PF01494.19 EER28730.1 - 4.8e-29 101.7 0.0 6.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EER28730.1 - 1.2e-08 34.3 0.0 0.0019 17.2 0.1 2.5 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 EER28730.1 - 4e-08 32.9 0.1 5.2e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EER28730.1 - 9.1e-08 32.1 5.8 3.3e-05 23.6 2.7 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER28730.1 - 1.5e-05 25.2 2.3 2.4e-05 24.5 1.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EER28730.1 - 2.9e-05 23.3 1.0 6.5e-05 22.2 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 EER28730.1 - 0.00014 22.4 0.0 0.0013 19.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER28730.1 - 0.0013 18.0 0.2 0.011 15.0 0.5 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER28730.1 - 0.0023 16.7 0.9 0.0088 14.8 1.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EER28730.1 - 0.0024 17.0 0.6 0.03 13.4 0.6 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EER28730.1 - 0.0031 16.9 0.8 0.0052 16.2 0.8 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EER28730.1 - 0.013 14.8 0.0 0.044 13.1 0.1 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EER28730.1 - 0.03 13.6 0.4 0.071 12.4 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EER28730.1 - 0.036 13.2 2.3 0.057 12.5 2.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 EER28730.1 - 0.24 10.6 0.2 0.42 9.8 0.2 1.3 1 0 0 1 1 1 0 Thi4 family DUF3818 PF12825.7 EER28731.1 - 7.1e-129 429.7 6.9 1.4e-128 428.7 6.9 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EER28731.1 - 7.8e-40 135.9 0.7 1.5e-39 134.9 0.7 1.4 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EER28731.1 - 3.9e-11 42.9 0.1 1.3e-09 38.1 0.0 3.3 3 1 0 3 3 3 1 PX domain GFD1 PF17331.2 EER28731.1 - 0.22 11.7 2.6 0.63 10.3 2.6 1.7 1 0 0 1 1 1 0 GFD1 mRNA transport factor zf-GRF PF06839.12 EER28732.1 - 0.047 13.8 0.6 0.1 12.7 0.6 1.6 1 0 0 1 1 1 0 GRF zinc finger Met_10 PF02475.16 EER28733.1 - 2.6e-64 216.6 0.0 3.6e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RNA_pol_Rpb4 PF03874.16 EER28734.1 - 4.7e-22 78.6 5.2 7.6e-22 77.9 5.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 EER28734.1 - 0.0079 15.8 0.7 0.011 15.4 0.7 1.2 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein AMP-binding PF00501.28 EER28735.1 - 1.9e-71 240.9 0.0 3.2e-71 240.1 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER28735.1 - 3.6e-09 37.5 0.0 7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RhoGAP PF00620.27 EER28736.1 - 1.1e-34 119.5 0.0 2.3e-34 118.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EER28736.1 - 2.9e-29 101.1 35.9 1.1e-10 41.5 8.3 4.9 5 0 0 5 5 5 4 LIM domain Nbl1_Borealin_N PF10444.9 EER28737.1 - 1.5e-19 69.4 4.3 2.4e-19 68.7 4.3 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 EER28738.1 - 4.3e-20 72.4 0.0 1.4e-19 70.7 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EER28738.1 - 5.3e-05 23.5 0.3 7.9e-05 23.0 0.3 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EER28738.1 - 0.0051 16.7 0.1 0.0097 15.7 0.1 1.4 1 1 0 1 1 1 1 Ssl1-like UIM PF02809.20 EER28738.1 - 0.018 14.9 0.3 0.044 13.7 0.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif Sybindin PF04099.12 EER28739.1 - 2.1e-48 163.9 0.0 3.3e-48 163.3 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EER28739.1 - 1.5e-08 34.8 0.0 2.6e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region UQ_con PF00179.26 EER28740.1 - 1.2e-41 141.7 0.0 1.5e-30 105.7 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER28740.1 - 2.3e-09 37.0 0.0 4.7e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B UEV PF05743.13 EER28740.1 - 0.0089 15.9 0.0 0.32 10.9 0.0 2.5 2 1 0 2 2 2 1 UEV domain RWD PF05773.22 EER28740.1 - 0.011 16.1 0.0 0.18 12.1 0.0 2.6 2 1 0 2 2 2 0 RWD domain p450 PF00067.22 EER28741.1 - 1.7e-24 86.4 0.0 2.2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.19 EER28742.1 - 3e-48 164.2 0.1 2.5e-47 161.2 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EER28742.1 - 1.2e-18 67.5 0.4 4e-18 65.8 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EER28742.1 - 5.8e-11 42.0 0.0 3.5e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EER28742.1 - 1.1e-09 38.2 0.2 1.2e-06 28.2 0.2 3.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EER28742.1 - 2.3e-05 23.6 0.1 6.5e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 EER28742.1 - 0.047 13.6 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 KR domain Pkinase PF00069.25 EER28743.1 - 5.9e-14 52.1 0.1 1.2e-08 34.7 0.1 2.0 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER28743.1 - 0.0022 17.3 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2861 PF11060.8 EER28744.1 - 0.031 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) RecQ5 PF06959.11 EER28745.1 - 0.04 13.9 1.2 0.062 13.3 1.2 1.4 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) Pkinase PF00069.25 EER28746.1 - 8.8e-58 195.7 0.0 6.6e-38 130.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER28746.1 - 1.1e-29 103.5 0.0 3.4e-22 79.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EER28746.1 - 4.2e-11 43.0 0.0 8.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EER28746.1 - 1.7e-07 30.9 0.0 4.7e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EER28746.1 - 7.1e-05 22.9 0.1 0.0047 16.9 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS PF00989.25 EER28746.1 - 0.00056 19.9 0.2 0.0016 18.4 0.1 1.9 2 0 0 2 2 1 1 PAS fold PAS_9 PF13426.7 EER28746.1 - 0.0016 18.6 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 PAS domain Haspin_kinase PF12330.8 EER28746.1 - 0.0082 15.1 0.0 0.0082 15.1 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EER28746.1 - 0.0099 15.3 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EER28746.1 - 0.024 14.3 0.1 2.1 7.9 0.0 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EER28746.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EER28746.1 - 0.27 10.2 0.0 0.55 9.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-3_zeta PF05091.12 EER28747.1 - 3.4e-204 679.6 0.0 4.2e-204 679.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3909 PF13077.6 EER28747.1 - 0.087 13.0 0.1 3.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3909) bZIP_1 PF00170.21 EER28748.1 - 0.00035 20.6 8.3 0.00069 19.7 8.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor TEX13 PF15186.6 EER28748.1 - 0.65 9.7 6.8 1.2 8.9 6.8 1.3 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family bZIP_2 PF07716.15 EER28748.1 - 7.8 6.7 14.5 10 6.3 11.6 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Pkinase PF00069.25 EER28749.1 - 1.6e-29 103.1 0.0 1.8e-28 99.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER28749.1 - 1.3e-08 34.4 0.0 2.9e-07 30.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EER28749.1 - 0.017 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Amidase PF01425.21 EER28750.1 - 1.3e-99 334.3 0.0 1.5e-99 334.0 0.0 1.0 1 0 0 1 1 1 1 Amidase Acetyltransf_3 PF13302.7 EER28752.1 - 2e-12 47.9 0.0 2.8e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER28752.1 - 1.2e-06 28.7 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EER28752.1 - 0.0054 16.9 0.0 0.0088 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 3-dmu-9_3-mt PF06983.13 EER28754.1 - 2e-36 125.0 0.1 3e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase dTDP_sugar_isom PF00908.17 EER28754.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase DUF3546 PF12066.8 EER28755.1 - 1.3e-30 105.9 1.9 1.3e-30 105.9 1.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EER28755.1 - 1.8e-12 46.8 0.1 4.1e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EER28755.1 - 4.6e-12 46.7 0.2 1.4e-11 45.1 0.2 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 CBFB_NFYA PF02045.15 EER28756.1 - 3.2e-28 98.1 4.6 3.2e-28 98.1 4.6 3.1 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 EER28756.1 - 0.078 12.1 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Hus1-like protein Kinesin PF00225.23 EER28757.1 - 1.9e-112 375.5 0.4 6.8e-112 373.7 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 EER28757.1 - 2e-45 155.2 0.0 5.8e-45 153.7 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 EER28757.1 - 1.5e-36 126.3 13.4 8.2e-31 107.5 0.2 3.7 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 EER28757.1 - 1.3e-24 86.8 0.0 3.6e-24 85.4 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 EER28757.1 - 3.6e-07 30.5 0.3 1.2e-06 28.8 0.3 2.0 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.26 EER28757.1 - 1.9e-06 28.1 0.3 2.9e-05 24.3 0.1 3.1 3 0 0 3 3 3 1 FHA domain PH PF00169.29 EER28757.1 - 1.4e-05 25.5 0.0 3.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 PH domain Yop-YscD_cpl PF16697.5 EER28757.1 - 0.0007 19.9 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Hat1_N PF10394.9 EER28757.1 - 0.13 12.5 0.7 0.63 10.3 0.5 2.3 2 0 0 2 2 2 0 Histone acetyl transferase HAT1 N-terminus UPF0242 PF06785.11 EER28757.1 - 0.24 11.5 15.9 0.48 10.5 0.5 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Phosphodiest PF01663.22 EER28758.1 - 3.1e-89 300.0 0.8 4e-89 299.7 0.8 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EER28758.1 - 0.00017 21.1 0.1 0.017 14.5 0.1 2.4 1 1 0 1 1 1 1 Sulfatase LptF_LptG PF03739.14 EER28758.1 - 0.057 12.3 0.0 0.087 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Ofd1_CTDD PF10637.9 EER28760.1 - 5.7e-93 310.9 0.0 1.3e-89 300.0 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EER28760.1 - 5.1e-25 88.0 0.0 1.7e-24 86.3 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EER28760.1 - 3e-12 47.2 0.0 6.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HLH PF00010.26 EER28761.1 - 5.1e-15 55.2 1.4 1.1e-14 54.1 1.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DivIC PF04977.15 EER28761.1 - 0.026 14.3 1.3 0.047 13.5 1.3 1.3 1 0 0 1 1 1 0 Septum formation initiator Rac1 PF09632.10 EER28761.1 - 0.044 13.0 0.2 0.064 12.4 0.2 1.2 1 0 0 1 1 1 0 Rac1-binding domain AAA_23 PF13476.6 EER28761.1 - 0.07 13.6 1.0 0.11 13.0 1.0 1.3 1 0 0 1 1 1 0 AAA domain F-box_4 PF15966.5 EER28763.1 - 0.006 16.4 0.1 0.012 15.5 0.1 1.5 1 1 0 1 1 1 1 F-box F-box-like PF12937.7 EER28763.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EER28763.1 - 0.14 12.1 0.2 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 F-box domain TAFII55_N PF04658.13 EER28764.1 - 2.3e-54 183.5 0.0 4.4e-54 182.5 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region MFS_1 PF07690.16 EER28765.1 - 2.1e-19 69.7 44.8 2.1e-19 69.7 44.8 3.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER28765.1 - 6.1e-08 31.9 9.4 6.1e-08 31.9 9.4 3.6 3 1 1 4 4 4 1 Sugar (and other) transporter TMEM215 PF15746.5 EER28765.1 - 0.028 13.9 2.2 0.058 12.8 2.2 1.5 1 0 0 1 1 1 0 TMEM215 family Pyr_redox_3 PF13738.6 EER28767.1 - 8.3e-17 61.4 0.0 1.4e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EER28767.1 - 3.2e-10 39.1 0.0 0.00023 19.8 0.0 2.7 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EER28767.1 - 5.3e-08 32.4 0.0 5.2e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER28767.1 - 7.7e-08 32.5 0.1 0.0033 17.4 0.0 3.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 EER28767.1 - 6.9e-06 25.4 0.0 5.3e-05 22.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EER28767.1 - 3.6e-05 23.5 0.2 1.3 8.5 0.0 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EER28767.1 - 6.4e-05 22.3 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EER28767.1 - 0.00017 20.4 0.0 0.027 13.2 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 EER28767.1 - 0.00095 19.4 0.0 0.0028 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EER28767.1 - 0.013 14.6 0.0 0.071 12.1 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 EER28767.1 - 0.046 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EER28767.1 - 0.12 11.4 0.0 27 3.7 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A E1-E2_ATPase PF00122.20 EER28767.1 - 0.19 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase ketoacyl-synt PF00109.26 EER28768.1 - 4.8e-69 232.8 0.0 1.1e-68 231.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 EER28768.1 - 5.2e-68 229.5 0.0 7.5e-68 228.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EER28768.1 - 8.5e-55 185.4 0.0 1.7e-54 184.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.21 EER28768.1 - 1.1e-52 179.5 0.0 2e-52 178.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EER28768.1 - 1e-29 103.0 0.1 2.4e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EER28768.1 - 2.5e-21 76.2 0.0 7.5e-21 74.7 0.0 1.9 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EER28768.1 - 1.6e-08 34.3 0.0 3.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.23 EER28768.1 - 8.7e-05 22.0 0.2 0.00021 20.7 0.2 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EER28768.1 - 9.3e-05 22.7 0.1 0.00032 21.0 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 EER28768.1 - 0.0031 17.4 0.0 0.0095 15.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 EER28768.1 - 0.0049 16.7 1.5 0.023 14.5 0.2 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.26 EER28768.1 - 0.036 14.1 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2834 PF11196.8 EER28769.1 - 0.00012 22.3 1.0 0.00012 22.3 1.0 4.0 3 2 0 3 3 3 1 Protein of unknown function (DUF2834) VIT1 PF01988.19 EER28769.1 - 0.16 11.8 1.7 0.31 10.9 1.7 1.5 1 0 0 1 1 1 0 VIT family Glyco_hydro_43 PF04616.14 EER28770.1 - 6.7e-36 124.1 0.1 9.5e-36 123.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.16 EER28770.1 - 0.00061 18.8 0.1 0.002 17.1 0.0 1.9 2 1 0 2 2 2 1 Levansucrase/Invertase vWA-TerF-like PF10138.9 EER28771.1 - 2.7e-06 27.7 0.0 4.3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.6 EER28771.1 - 0.004 17.4 26.8 0.004 17.4 26.8 2.9 2 1 0 2 2 2 1 Proline-rich VWA PF00092.28 EER28771.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Homeobox_KN PF05920.11 EER28772.1 - 1.7e-21 75.8 0.4 1.7e-21 75.8 0.4 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EER28772.1 - 4.8e-07 29.5 0.1 9.7e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain WRW PF10206.9 EER28772.1 - 0.8 10.1 3.0 1.8 9.0 1.6 2.1 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f SRP_TPR_like PF17004.5 EER28774.1 - 1e-18 67.4 1.1 1e-18 67.4 1.1 2.3 3 0 0 3 3 2 1 Putative TPR-like repeat SRP72 PF08492.12 EER28774.1 - 1e-16 61.1 14.5 1e-16 61.1 14.5 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 EER28774.1 - 1.8e-10 41.2 6.6 0.0088 16.5 0.0 6.1 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EER28774.1 - 7.1e-08 32.0 12.9 0.017 15.2 0.1 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EER28774.1 - 3.8e-07 30.4 12.8 3.6 8.7 0.1 7.6 5 1 3 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EER28774.1 - 6.1e-06 26.0 1.4 0.043 14.0 0.2 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EER28774.1 - 8.4e-06 25.9 5.5 0.0008 19.6 0.2 4.1 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EER28774.1 - 0.00026 20.7 6.8 0.13 12.1 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EER28774.1 - 0.00073 20.1 9.6 1.4 9.6 1.6 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EER28774.1 - 0.0048 16.5 1.2 3.3 7.5 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_20 PF14561.6 EER28774.1 - 0.013 15.8 2.5 8.1 6.9 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER28774.1 - 0.014 15.7 0.2 0.014 15.7 0.2 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EER28774.1 - 0.021 15.4 11.0 27 5.7 0.2 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 EER28774.1 - 0.051 13.6 0.1 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EER28774.1 - 0.23 12.2 3.9 9.5 7.2 0.1 4.5 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EER28774.1 - 2 8.4 8.6 0.83 9.6 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat FAD_binding_1 PF00667.20 EER28775.1 - 4.5e-46 157.2 0.0 6.4e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EER28775.1 - 4.5e-09 36.9 0.0 1.6e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Med20 PF08612.11 EER28777.1 - 2.9e-76 255.8 0.0 3.5e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.32 EER28778.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EER28778.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EER28778.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EER28778.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EER28778.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EER28778.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EER28778.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EER28778.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EER28778.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EER28778.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EER28778.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EER28778.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EER28778.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EER28778.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 EER28778.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 EER28778.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EER28778.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 EER28778.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 EER28778.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 EER28778.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 EER28778.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 EER28778.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 EER28778.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 EER28778.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 EER28778.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) SNARE PF05739.19 EER28779.1 - 9e-14 51.2 0.3 2.3e-13 49.9 0.3 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EER28779.1 - 0.00088 19.0 6.7 0.048 13.3 0.2 2.1 2 0 0 2 2 2 2 Syntaxin LUC7 PF03194.15 EER28779.1 - 0.044 13.4 1.5 0.085 12.5 1.5 1.4 1 0 0 1 1 1 0 LUC7 N_terminus DNA_repr_REX1B PF14966.6 EER28779.1 - 0.17 12.5 0.2 0.17 12.5 0.2 2.4 3 1 0 3 3 3 0 DNA repair REX1-B MCPsignal PF00015.21 EER28779.1 - 0.35 10.7 7.0 1.4 8.7 0.4 2.7 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EER28779.1 - 2.2 8.6 3.8 77 3.7 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CTD_bind PF04818.13 EER28780.1 - 3.7e-18 66.1 0.1 1.3e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EER28780.1 - 0.077 13.0 1.1 0.1 12.6 0.1 1.6 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 MCD_N PF17408.2 EER28780.1 - 0.53 10.5 3.5 2.3 8.4 0.1 3.4 4 0 0 4 4 4 0 Malonyl-CoA decarboxylase N-terminal domain SKA2 PF16740.5 EER28780.1 - 1.2 8.9 6.7 0.68 9.7 3.6 2.1 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DnaG_DnaB_bind PF08278.11 EER28780.1 - 5.1 7.7 8.8 1.8 9.1 3.0 2.5 2 1 0 2 2 2 0 DNA primase DnaG DnaB-binding Clathrin_lg_ch PF01086.17 EER28781.1 - 2.7e-74 250.1 3.3 3e-74 250.0 3.3 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.6 EER28781.1 - 0.025 14.4 0.7 0.049 13.4 0.7 1.5 1 0 0 1 1 1 0 Integrase core domain GAPT PF11770.8 EER28781.1 - 0.43 10.4 1.4 0.66 9.8 1.4 1.3 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Acyl_transf_3 PF01757.22 EER28782.1 - 2.1e-21 76.4 30.6 4.4e-21 75.3 30.6 1.5 1 1 0 1 1 1 1 Acyltransferase family DUF4064 PF13273.6 EER28782.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) Acyl_transf_3 PF01757.22 EER28783.1 - 3.6e-27 95.3 40.7 7.8e-27 94.2 40.7 1.6 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.12 EER28783.1 - 0.14 12.0 13.0 0.036 14.0 8.6 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF418) Mannosyl_trans3 PF11051.8 EER28784.1 - 1.6e-60 204.8 0.0 3.1e-37 128.4 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative CDC37_N PF03234.14 EER28785.1 - 1.5e-49 168.2 0.7 1.5e-49 168.2 0.7 3.0 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EER28785.1 - 1.2e-42 144.5 0.6 4.2e-42 142.8 0.1 2.2 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EER28785.1 - 6.5e-36 122.5 1.9 6.5e-36 122.5 1.9 2.3 2 1 0 2 2 2 1 Cdc37 C terminal domain ABC_membrane PF00664.23 EER28786.1 - 1.2e-50 172.7 8.1 1.6e-50 172.3 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EER28786.1 - 1.1e-35 123.2 0.0 3.4e-35 121.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EER28786.1 - 1.1e-05 25.0 0.0 0.00097 18.6 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EER28786.1 - 0.0029 17.9 0.1 0.019 15.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EER28786.1 - 0.0046 17.3 0.1 0.022 15.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EER28786.1 - 0.0084 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EER28786.1 - 0.022 14.5 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 EER28786.1 - 0.026 14.6 0.0 0.58 10.2 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA PF00004.29 EER28786.1 - 0.039 14.4 0.0 0.18 12.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EER28786.1 - 0.041 13.6 0.0 0.15 11.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EER28786.1 - 0.059 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_ATPase PF09818.9 EER28786.1 - 0.12 11.1 0.9 0.51 9.1 0.2 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 EER28786.1 - 0.14 12.4 0.9 1.8 8.9 0.9 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 EER28786.1 - 0.48 10.9 4.2 0.79 10.2 0.2 2.6 3 0 0 3 3 3 0 AAA domain Nucleoside_tran PF01733.18 EER28787.1 - 1.5e-41 142.8 20.1 2.4e-29 102.7 3.6 2.6 2 1 1 3 3 3 2 Nucleoside transporter MFS_1 PF07690.16 EER28787.1 - 2.7e-13 49.6 26.3 2.1e-05 23.6 4.5 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Lactamase_B PF00753.27 EER28788.1 - 0.014 15.4 0.3 0.018 15.1 0.3 1.2 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Fungal_trans PF04082.18 EER28789.1 - 1.2e-10 40.9 0.2 3.6e-10 39.3 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EER28789.1 - 9.2e-07 29.0 2.7 9.2e-07 29.0 2.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 EER28789.1 - 2.2e-06 27.8 15.0 0.006 17.0 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER28789.1 - 0.0019 18.9 12.8 0.22 12.5 4.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EER28789.1 - 0.074 13.5 3.7 0.52 10.8 0.7 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 EER28789.1 - 0.27 11.4 2.1 11 6.3 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Actin_micro PF17003.5 EER28789.1 - 0.28 10.3 0.4 4.2 6.4 0.5 2.1 1 1 0 1 1 1 0 Putative actin-like family CMD PF02627.20 EER28790.1 - 6.6e-21 74.2 0.1 9.8e-21 73.6 0.1 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TFX_C PF14601.6 EER28790.1 - 0.04 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA_binding protein, TFX, C-term NAD_binding_11 PF14833.6 EER28791.1 - 2.5e-22 79.4 0.0 3.8e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EER28791.1 - 4.1e-21 75.8 0.0 7.1e-21 75.0 0.0 1.4 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EER28791.1 - 0.032 14.8 0.0 0.081 13.5 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Haspin_kinase PF12330.8 EER28792.1 - 1.4e-41 142.7 0.0 3.6e-41 141.3 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain DUF1518 PF07469.12 EER28793.1 - 0.25 11.8 0.1 0.25 11.8 0.1 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1518) DUF1682 PF07946.14 EER28794.1 - 1e-116 389.7 2.0 1.2e-116 389.5 2.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Glyco_tran_WecB PF03808.13 EER28794.1 - 0.0086 16.0 0.1 0.38 10.7 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family PPR PF01535.20 EER28795.1 - 0.029 14.6 0.0 8.5 6.9 0.0 2.9 2 0 0 2 2 2 0 PPR repeat Thiamine_BP PF01910.17 EER28796.1 - 1.2e-29 102.1 0.0 1.3e-29 101.9 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Ins_P5_2-kin PF06090.12 EER28797.1 - 9.3e-51 173.2 0.0 2.2e-50 172.0 0.0 1.6 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase YEATS PF03366.16 EER28798.1 - 2.1e-36 123.7 0.9 3.3e-36 123.1 0.9 1.3 1 0 0 1 1 1 1 YEATS family M16C_assoc PF08367.11 EER28798.1 - 0.33 10.0 4.7 0.46 9.6 4.7 1.2 1 0 0 1 1 1 0 Peptidase M16C associated NAD_binding_10 PF13460.6 EER28799.1 - 3.3e-06 27.1 0.0 3.2e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EER28799.1 - 7.2e-05 22.4 0.0 0.00025 20.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EER28799.1 - 0.00078 18.5 0.0 0.0036 16.3 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EER28799.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EER28799.1 - 0.024 14.0 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EER28799.1 - 0.032 13.4 0.0 0.96 8.6 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.17 EER28799.1 - 0.098 11.7 0.0 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EER28799.1 - 0.11 11.6 0.0 0.83 8.7 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SYF2 PF08231.12 EER28800.1 - 1e-54 185.3 10.9 1e-54 185.3 10.9 1.8 2 0 0 2 2 2 1 SYF2 splicing factor CHASE3 PF05227.13 EER28800.1 - 1.2 9.1 8.2 8.2 6.3 3.4 2.3 2 0 0 2 2 2 0 CHASE3 domain Velvet PF11754.8 EER28803.1 - 1.5e-44 152.9 0.0 1.7e-24 87.2 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Sel1 PF08238.12 EER28804.1 - 0.00015 22.3 2.6 0.35 11.6 0.4 3.7 3 0 0 3 3 3 1 Sel1 repeat TPR_2 PF07719.17 EER28804.1 - 0.0013 18.7 0.7 0.92 9.8 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER28804.1 - 0.0017 18.1 1.4 2.4 8.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EER28804.1 - 0.0024 17.5 0.1 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 EER28804.1 - 0.047 13.9 7.2 1.7 9.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER28804.1 - 0.096 13.0 1.3 5.8 7.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EER28804.1 - 4.4 7.9 6.3 1.4 9.4 0.2 3.3 4 1 1 5 5 5 0 Tetratricopeptide repeat PH_10 PF15411.6 EER28805.1 - 1.2e-26 93.3 0.1 2.2e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EER28805.1 - 7.6e-14 52.3 0.0 1.4e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EER28805.1 - 1.1e-08 35.1 0.1 1e-07 32.0 0.0 2.5 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EER28805.1 - 4.4e-06 27.3 0.0 1.7e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 EER28805.1 - 0.0018 18.5 8.6 0.0018 18.5 8.6 2.0 2 0 0 2 2 2 1 Ring finger domain Zn_ribbon_17 PF17120.5 EER28805.1 - 0.027 14.1 8.9 0.014 15.0 5.6 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EER28805.1 - 0.058 13.4 8.7 0.11 12.4 8.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 EER28805.1 - 0.07 13.4 4.9 0.16 12.3 4.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EER28805.1 - 0.075 12.9 9.0 0.18 11.7 9.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER28805.1 - 0.09 12.6 7.9 0.2 11.5 7.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GCV_T_C PF08669.11 EER28805.1 - 0.13 12.2 0.3 0.41 10.6 0.1 1.9 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain zf-RING_11 PF17123.5 EER28805.1 - 0.2 11.4 4.0 0.66 9.8 4.0 2.0 1 0 0 1 1 1 0 RING-like zinc finger zf-RING-like PF08746.11 EER28805.1 - 0.73 10.2 7.9 1.5 9.2 7.9 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 EER28805.1 - 8.4 6.5 8.5 28 4.9 8.5 2.0 1 1 0 1 1 1 0 Zinc-finger Ribosomal_L12 PF00542.19 EER28806.1 - 1.1e-20 73.8 8.3 1.2e-19 70.4 6.9 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EER28806.1 - 9.6e-13 47.6 8.0 9.6e-13 47.6 8.0 3.3 5 1 0 5 5 5 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 EER28806.1 - 0.025 14.3 1.6 0.081 12.7 0.6 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F DAHP_snth_FXD PF18152.1 EER28806.1 - 0.14 12.1 0.2 0.44 10.4 0.2 1.8 1 0 0 1 1 1 0 DAHP synthase ferredoxin-like domain DUF3138 PF11336.8 EER28806.1 - 1.5 7.3 5.8 0.26 9.8 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Cpn60_TCP1 PF00118.24 EER28807.1 - 3.1e-150 501.1 6.8 3.5e-150 500.9 6.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PrpR_N PF06506.11 EER28807.1 - 0.006 16.2 0.1 0.023 14.3 0.1 2.0 2 0 0 2 2 2 1 Propionate catabolism activator EAL PF00563.20 EER28807.1 - 0.049 13.2 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 EAL domain E1_dh PF00676.20 EER28808.1 - 3.4e-114 380.8 0.1 4.1e-114 380.5 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EER28808.1 - 2.7e-05 23.5 0.1 5.1e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EER28808.1 - 0.007 16.2 1.7 0.013 15.3 1.7 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain S4 PF01479.25 EER28809.1 - 2.7e-15 55.8 0.0 5.6e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EER28809.1 - 0.026 14.3 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 S4 domain HSP70 PF00012.20 EER28809.1 - 0.12 10.6 5.1 0.17 10.1 5.1 1.2 1 0 0 1 1 1 0 Hsp70 protein RNA_pol_Rpc4 PF05132.14 EER28809.1 - 2.2 8.7 7.9 0.92 9.9 0.7 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 GDPD PF03009.17 EER28810.1 - 2.9e-19 69.8 0.0 5e-19 69.1 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3636 PF12331.8 EER28811.1 - 1e-49 168.2 0.2 2.5e-49 166.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 EER28811.1 - 0.00077 18.1 2.8 0.31 9.5 1.3 2.2 2 0 0 2 2 2 2 DNA damage checkpoint protein TPR_MLP1_2 PF07926.12 EER28811.1 - 0.24 11.5 15.4 1.8 8.6 6.6 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2205 PF10224.9 EER28811.1 - 0.98 9.5 8.3 0.69 9.9 3.4 2.5 1 1 1 2 2 2 0 Short coiled-coil protein Prok-TraM PF09228.10 EER28811.1 - 1 9.7 6.8 1.6 9.1 1.4 2.6 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Herpes_UL6 PF01763.16 EER28811.1 - 1.9 6.9 7.2 31 2.9 7.1 2.1 2 0 0 2 2 2 0 Herpesvirus UL6 like APG6_N PF17675.1 EER28811.1 - 4.2 7.9 18.2 1.8 9.1 2.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 EER28811.1 - 7.1 7.3 12.9 30 5.3 6.2 2.5 1 1 1 2 2 2 0 Initiation control protein YabA CTP_transf_1 PF01148.20 EER28812.1 - 2.3e-82 276.7 23.7 3.1e-82 276.3 23.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Cyclin_N PF00134.23 EER28813.1 - 9.3e-09 35.1 0.1 1.7e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain zf-C2H2_4 PF13894.6 EER28814.1 - 6.5e-06 26.6 35.1 2.6 9.1 5.5 6.4 6 0 0 6 6 6 5 C2H2-type zinc finger zf-RRPl_C4 PF17026.5 EER28814.1 - 0.0015 18.6 14.3 0.0025 17.9 5.4 2.5 1 1 2 3 3 3 1 Putative ribonucleoprotein zinc-finger pf C4 type zf-met PF12874.7 EER28814.1 - 0.0026 18.1 6.0 0.031 14.7 1.3 5.4 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EER28814.1 - 0.0039 17.4 2.9 0.0039 17.4 2.9 6.0 6 1 1 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EER28814.1 - 0.048 14.1 40.2 2.1 9.0 0.5 6.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 EER28814.1 - 0.12 12.2 0.1 0.12 12.2 0.1 4.6 4 1 1 5 5 5 0 zinc-finger C2H2-type DUF4187 PF13821.6 EER28814.1 - 0.24 11.2 17.2 0.13 12.1 1.9 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4187) zf-C2H2_3rep PF18868.1 EER28814.1 - 0.56 10.9 18.9 3.8 8.2 1.0 3.6 1 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats GST_N_2 PF13409.6 EER28815.1 - 7.2e-12 45.4 0.5 2.1e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EER28815.1 - 2.9e-09 37.2 0.1 7e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EER28815.1 - 6.8e-07 29.2 0.2 1.5e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EER28815.1 - 2.5e-06 27.7 0.1 4.3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EER28815.1 - 0.0003 21.3 0.0 0.0005 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EER28815.1 - 0.0087 16.2 0.0 0.053 13.7 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EER28815.1 - 0.027 14.7 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fructosamin_kin PF03881.14 EER28816.1 - 2.7e-57 194.2 0.0 5.1e-48 163.7 0.0 2.6 3 0 0 3 3 3 2 Fructosamine kinase APH PF01636.23 EER28816.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Arm PF00514.23 EER28817.1 - 4.1e-18 64.7 4.8 0.0011 19.0 0.0 9.6 11 0 0 11 11 11 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EER28817.1 - 0.00062 20.2 3.4 0.33 11.5 0.0 5.6 5 0 0 5 5 5 1 HEAT-like repeat DUF3361 PF11841.8 EER28817.1 - 0.056 13.4 2.3 0.39 10.7 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) HEAT PF02985.22 EER28817.1 - 0.47 10.8 13.8 1.5 9.3 0.0 6.2 7 0 0 7 7 7 0 HEAT repeat Cyclin PF08613.11 EER28818.1 - 1.5e-31 110.0 0.3 3.2e-31 108.9 0.3 1.8 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EER28818.1 - 0.00015 21.5 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain dCMP_cyt_deam_1 PF00383.23 EER28819.1 - 0.00021 21.1 1.7 0.0057 16.5 1.7 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EER28819.1 - 0.028 14.2 0.1 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 MafB19-like deaminase Ge1_WD40 PF16529.5 EER28820.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Importin_rep_6 PF18829.1 EER28820.1 - 0.014 15.5 0.4 0.048 13.8 0.0 2.1 2 0 0 2 2 2 0 Importin repeat 6 DUF445 PF04286.12 EER28820.1 - 0.15 11.9 16.8 0.4 10.4 12.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF445) Glyoxalase PF00903.25 EER28821.1 - 0.0003 21.0 0.0 0.00058 20.1 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Chs7 PF12271.8 EER28822.1 - 2.9e-87 292.7 5.4 3.4e-87 292.4 5.4 1.1 1 0 0 1 1 1 1 Chitin synthase export chaperone DLH PF01738.18 EER28823.1 - 1.7e-21 76.8 0.0 2e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EER28823.1 - 0.0049 16.5 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 EER28823.1 - 0.024 14.2 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase BAAT_C PF08840.11 EER28823.1 - 0.041 13.8 0.0 0.29 11.0 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cadherin PF00028.17 EER28823.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 Cadherin domain UCH PF00443.29 EER28824.1 - 1.9e-45 155.4 0.0 3.3e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER28824.1 - 1.8e-13 50.8 0.0 4.4e-12 46.2 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EER28824.1 - 0.25 10.8 0.0 36 3.7 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-C3HC4 PF00097.25 EER28825.1 - 3.3e-07 30.1 7.3 6.4e-07 29.1 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER28825.1 - 2e-06 27.5 7.9 5.2e-06 26.2 2.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER28825.1 - 2.1e-06 27.6 3.4 2.1e-06 27.6 3.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EER28825.1 - 6.6e-06 26.4 9.7 2.8e-05 24.4 8.2 2.3 1 1 1 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.6 EER28825.1 - 7e-06 26.1 5.0 3.8e-05 23.8 5.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EER28825.1 - 7.9e-06 25.6 6.4 1.7e-05 24.5 6.4 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER28825.1 - 1.8e-05 24.6 3.6 3.8e-05 23.5 3.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EER28825.1 - 0.0096 15.8 7.7 0.046 13.6 7.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EER28825.1 - 0.066 13.0 4.6 0.12 12.2 4.6 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EER28825.1 - 1.7 9.0 6.6 5.6 7.3 6.6 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain ERG4_ERG24 PF01222.17 EER28826.1 - 1.8e-142 475.1 19.3 2.2e-142 474.8 19.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Hva1_TUDOR PF11160.8 EER28827.1 - 2.5e-14 53.2 2.0 3.4e-14 52.7 2.0 1.2 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain GFO_IDH_MocA PF01408.22 EER28828.1 - 1.9e-23 83.6 0.0 3.4e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Na_H_Exchanger PF00999.21 EER28829.1 - 2.8e-42 144.9 17.2 3.7e-42 144.5 17.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1206 PF06724.11 EER28829.1 - 0.022 14.8 3.6 0.022 14.8 3.6 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) RNase_H PF00075.24 EER28830.1 - 5.9e-38 130.3 0.0 1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 EER28830.1 - 7.5e-37 125.4 9.4 1.2e-18 67.1 0.8 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RVT_3 PF13456.6 EER28830.1 - 0.072 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase-like FMN_dh PF01070.18 EER28831.1 - 2.1e-104 349.3 0.0 2.4e-104 349.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EER28831.1 - 1.1e-19 70.4 0.0 2.2e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EER28831.1 - 3.3e-07 29.8 0.1 5.4e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EER28831.1 - 5.3e-05 22.4 0.1 0.00021 20.4 0.0 1.9 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EER28831.1 - 0.062 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein NMO PF03060.15 EER28831.1 - 0.074 12.4 0.4 0.2 11.0 0.2 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.19 EER28831.1 - 0.17 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Tugs PF17840.1 EER28831.1 - 0.27 11.5 0.6 11 6.3 0.0 2.4 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain DUF202 PF02656.15 EER28832.1 - 2.7e-06 27.7 3.1 4.7e-06 26.9 1.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Myelin_PLP PF01275.19 EER28832.1 - 0.0095 15.8 1.1 0.012 15.5 1.1 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) 6PF2K PF01591.18 EER28833.1 - 4.6e-68 228.9 0.0 3.8e-47 160.5 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EER28833.1 - 1.8e-29 102.8 0.0 7.2e-24 84.6 0.0 2.5 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EER28833.1 - 0.0033 17.6 0.0 0.89 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF5128 PF17170.4 EER28833.1 - 0.0073 15.5 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 6-bladed beta-propeller KTI12 PF08433.10 EER28833.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 VTC PF09359.10 EER28834.1 - 3.5e-90 302.1 0.2 6e-90 301.4 0.2 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EER28834.1 - 5.6e-13 49.1 2.9 5.6e-13 49.1 2.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EER28834.1 - 3.7e-07 30.4 2.3 7.5e-05 22.8 0.1 4.8 2 2 2 4 4 4 3 SPX domain CYTH PF01928.21 EER28834.1 - 0.0044 17.0 0.2 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 CYTH domain DUF3435 PF11917.8 EER28836.1 - 0.041 12.8 2.0 0.087 11.7 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) GIDA_assoc PF13932.6 EER28836.1 - 0.23 11.6 3.3 0.38 10.9 3.3 1.3 1 0 0 1 1 1 0 GidA associated domain Prominin PF05478.11 EER28836.1 - 1.3 6.9 3.4 1.8 6.4 3.4 1.1 1 0 0 1 1 1 0 Prominin MFS_1 PF07690.16 EER28837.1 - 8.3e-37 126.9 30.3 9.5e-36 123.4 9.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER28837.1 - 2.2e-11 43.3 0.1 4.7e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_5 PF05631.14 EER28837.1 - 0.00019 20.5 0.4 0.00033 19.7 0.1 1.5 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM LacY_symp PF01306.19 EER28837.1 - 0.0038 16.1 1.4 0.0069 15.2 1.4 1.3 1 0 0 1 1 1 1 LacY proton/sugar symporter DUF1129 PF06570.11 EER28837.1 - 0.023 14.2 0.4 5.7 6.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) MFS_1_like PF12832.7 EER28837.1 - 0.046 12.6 1.6 0.32 9.8 1.6 2.5 1 1 0 1 1 1 0 MFS_1 like family MMU163 PF17119.5 EER28838.1 - 1.3e-117 391.4 0.1 1.7e-117 391.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Mcl1_mid PF12341.8 EER28839.1 - 5.6e-104 347.6 0.0 9.5e-103 343.6 0.0 2.6 2 1 1 3 3 3 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EER28839.1 - 7.1e-19 67.8 4.8 3.8e-07 30.7 0.0 7.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER28839.1 - 7.2e-17 61.5 0.1 7.8e-05 22.9 0.1 7.0 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EER28839.1 - 2.5e-09 36.7 0.1 1e-08 34.7 0.1 1.9 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 EER28839.1 - 0.0064 16.4 1.0 0.051 13.4 0.1 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DNA_pol_alpha_N PF12254.8 EER28839.1 - 0.013 15.5 4.5 0.05 13.7 4.5 1.9 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal MMS1_N PF10433.9 EER28839.1 - 0.038 12.6 0.0 0.17 10.5 0.0 1.9 2 1 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term PD40 PF07676.12 EER28839.1 - 0.042 13.8 0.2 14 5.8 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 EER28839.1 - 0.055 11.5 0.2 0.17 9.8 0.1 1.6 1 1 0 1 1 1 0 IKI3 family p450 PF00067.22 EER28840.1 - 3.2e-11 42.7 0.0 2.2e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 RNA12 PF10443.9 EER28841.1 - 6.2e-165 549.2 0.0 1.2e-164 548.3 0.0 1.5 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EER28841.1 - 5.2e-05 23.3 0.0 9.5e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EER28841.1 - 0.02 15.3 0.0 0.063 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 EER28841.1 - 0.028 14.2 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 EER28841.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) DUF3128 PF11326.8 EER28842.1 - 6e-28 97.0 6.5 1.3e-27 96.0 6.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) GATase_2 PF00310.21 EER28843.1 - 3e-171 569.8 0.0 4.3e-171 569.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EER28843.1 - 4.4e-155 516.4 0.0 6.7e-155 515.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EER28843.1 - 8.7e-114 379.7 0.0 2.4e-111 371.7 0.0 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EER28843.1 - 2.3e-85 285.0 5.2 3.8e-85 284.3 5.2 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EER28843.1 - 8e-25 87.7 0.2 7.2e-24 84.5 0.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EER28843.1 - 4e-21 74.9 0.1 8e-21 73.9 0.1 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 EER28843.1 - 1.8e-08 34.5 0.1 6.6e-08 32.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EER28843.1 - 1.6e-06 27.7 0.2 3.4e-06 26.6 0.2 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EER28843.1 - 2.1e-06 27.4 0.2 3.9e-06 26.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EER28843.1 - 2.6e-06 26.9 1.6 0.035 13.4 0.1 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EER28843.1 - 2.7e-06 27.8 0.1 0.0029 18.1 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EER28843.1 - 4.7e-06 26.4 2.5 0.0071 16.0 1.0 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EER28843.1 - 4.7e-05 22.6 1.5 0.00019 20.6 0.9 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EER28843.1 - 6.5e-05 21.8 0.4 6.5e-05 21.8 0.4 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 EER28843.1 - 0.00059 19.2 0.1 0.0012 18.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EER28843.1 - 0.01 15.1 0.2 0.03 13.6 0.2 1.7 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EER28843.1 - 0.012 14.7 2.9 0.012 14.7 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EER28843.1 - 0.029 13.7 1.2 0.57 9.4 0.1 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 EER28843.1 - 0.029 12.8 0.1 1.4 7.3 0.0 2.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_7 PF13241.6 EER28843.1 - 0.03 14.7 1.8 3.3 8.2 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 EER28843.1 - 0.036 14.2 0.9 8.7 6.4 0.1 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.18 EER28843.1 - 0.099 11.6 2.1 0.2 10.6 1.2 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.12 EER28843.1 - 0.13 11.3 0.3 0.3 10.1 0.3 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.23 EER28843.1 - 0.14 12.2 0.2 0.38 10.7 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MADF_DNA_bdg PF10545.9 EER28843.1 - 0.31 11.4 1.2 0.8 10.1 1.2 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like 2-Hacid_dh_C PF02826.19 EER28843.1 - 0.34 10.2 1.5 0.53 9.6 0.0 2.0 3 0 0 3 3 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PP2C PF00481.21 EER28844.1 - 1.4e-19 70.8 0.0 1.9e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EER28844.1 - 0.038 13.6 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C PS_Dcarbxylase PF02666.15 EER28845.1 - 1.4e-50 171.7 0.0 1.7e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase HSP70 PF00012.20 EER28847.1 - 1.7e-260 865.4 6.5 1.9e-260 865.2 6.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EER28847.1 - 8.1e-18 64.3 0.1 9.7e-17 60.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EER28847.1 - 0.0034 17.1 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EER28847.1 - 0.0083 16.5 3.9 5.5 7.5 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA StbA PF06406.11 EER28847.1 - 0.026 13.8 0.0 0.061 12.6 0.0 1.6 1 0 0 1 1 1 0 StbA protein Hydantoinase_A PF01968.18 EER28847.1 - 0.049 12.9 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Golgin_A5 PF09787.9 EER28847.1 - 2 7.8 6.2 0.83 9.1 3.4 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 5 CHZ PF09649.10 EER28848.1 - 6.2e-16 57.6 1.4 6.2e-16 57.6 1.4 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ Glyoxalase_6 PF18029.1 EER28849.1 - 0.0013 19.5 0.1 0.0019 19.0 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EER28849.1 - 0.0037 17.5 0.0 0.0056 16.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Use1 PF09753.9 EER28850.1 - 0.0042 16.8 0.1 0.0044 16.8 0.1 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Apc15p PF05841.11 EER28851.1 - 4.8e-14 53.2 0.7 1.2e-13 52.0 0.1 1.9 2 0 0 2 2 2 1 Apc15p protein FTA2 PF13095.6 EER28852.1 - 0.00046 19.9 0.1 0.00098 18.8 0.1 1.5 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EER28852.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EER28852.1 - 0.0094 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pyr_redox PF00070.27 EER28855.1 - 0.11 13.0 0.1 0.23 12.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.6 EER28856.1 - 6.5e-18 64.5 0.4 1.5e-17 63.3 0.4 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase FAT PF02259.23 EER28856.1 - 0.096 11.9 1.0 0.22 10.7 0.0 1.9 2 0 0 2 2 2 0 FAT domain DUF3435 PF11917.8 EER28857.1 - 5.5e-88 295.7 0.0 6.2e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) p450 PF00067.22 EER28858.1 - 2e-11 43.3 0.0 2.3e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 EER28859.1 - 1.7e-11 44.5 0.1 9.3e-11 42.1 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family HNH_2 PF13391.6 EER28860.1 - 5.4e-14 52.1 0.1 9.8e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease LPD16 PF18830.1 EER28860.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 16 APH PF01636.23 EER28861.1 - 4.7e-18 66.0 0.0 2.9e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EER28861.1 - 0.021 14.1 0.1 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase DUF1679 PF07914.11 EER28861.1 - 0.021 13.7 0.0 0.24 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Haspin_kinase PF12330.8 EER28861.1 - 0.089 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain EcKinase PF02958.20 EER28861.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.25 EER28862.1 - 3.7e-09 36.3 0.0 4.7e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 EER28863.1 - 1.3e-23 83.7 0.0 1.2e-22 80.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER28863.1 - 4.1e-14 52.5 0.0 2.5e-08 33.5 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 EER28863.1 - 0.00018 21.2 0.0 0.00039 20.1 0.0 1.4 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EER28863.1 - 0.0063 15.3 0.0 0.0097 14.7 0.0 1.4 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EER28863.1 - 0.037 14.0 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EER28863.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HCO3_cotransp PF00955.21 EER28864.1 - 9e-71 239.2 11.0 1.8e-38 132.7 6.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sas10_Utp3 PF04000.15 EER28866.1 - 1.2e-17 64.3 0.6 2.3e-17 63.4 0.0 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF4746 PF15928.5 EER28866.1 - 0.091 12.2 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TMEM40 PF15817.5 EER28867.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 40 family FMO-like PF00743.19 EER28868.1 - 1.5e-17 63.2 0.0 1e-16 60.5 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EER28868.1 - 1.4e-13 50.8 0.0 2.6e-12 46.6 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER28868.1 - 2.7e-11 43.3 0.0 7.9e-11 41.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER28868.1 - 4.1e-07 29.5 0.0 2.1e-05 23.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EER28868.1 - 1e-05 25.3 0.5 0.0033 17.1 0.9 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EER28868.1 - 1.1e-05 24.8 1.6 0.0083 15.4 0.2 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EER28868.1 - 2.3e-05 24.5 2.4 4.7e-05 23.5 0.1 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EER28868.1 - 4e-05 24.1 1.8 0.1 13.2 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER28868.1 - 0.00018 21.5 0.3 0.037 14.0 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EER28868.1 - 0.0019 18.3 0.3 3.4 7.7 0.0 2.6 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EER28868.1 - 0.004 17.1 0.3 0.0063 16.4 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EER28868.1 - 0.0044 17.5 0.0 0.19 12.2 0.0 2.4 2 1 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 EER28868.1 - 0.044 13.1 0.0 5.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EER28868.1 - 0.24 10.6 0.1 0.36 10.0 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EER28868.1 - 0.56 8.8 3.2 0.85 8.2 0.6 2.1 2 0 0 2 2 2 0 HI0933-like protein Retrotran_gag_2 PF14223.6 EER28871.1 - 0.00055 19.6 1.7 0.00086 19.0 0.0 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Neugrin PF06413.11 EER28871.1 - 0.022 14.8 5.0 0.04 13.9 5.0 1.4 1 0 0 1 1 1 0 Neugrin PepSY_TM_like_2 PF16357.5 EER28871.1 - 0.61 10.0 2.3 1.2 9.1 2.3 1.6 1 0 0 1 1 1 0 Putative PepSY_TM-like FGF-BP1 PF06473.12 EER28871.1 - 1.5 8.6 7.9 2.5 7.9 7.9 1.3 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) SOSSC PF15925.5 EER28871.1 - 9 7.7 8.3 27 6.1 8.4 1.9 1 1 0 1 1 1 0 SOSS complex subunit C Peptidase_S8 PF00082.22 EER28872.1 - 1.4e-32 113.2 16.8 2.3e-32 112.4 16.8 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER28872.1 - 1.3e-17 64.2 0.0 2.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Mito_carr PF00153.27 EER28873.1 - 9.8e-58 192.1 4.6 5.8e-19 67.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIIC_delta PF12657.7 EER28874.1 - 3e-44 151.2 0.4 5.8e-44 150.2 0.4 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EER28874.1 - 2.1e-32 111.1 1.5 5.3e-32 109.8 1.5 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DUF2793 PF10983.8 EER28874.1 - 0.096 12.6 0.0 0.3 11.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Myb_DNA-bind_3 PF12776.7 EER28875.1 - 7.4e-10 39.7 5.2 1.1e-09 39.1 5.2 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EER28875.1 - 0.0027 18.0 2.6 0.0045 17.3 2.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Glyco_trans_1_4 PF13692.6 EER28876.1 - 2.8e-07 31.0 0.0 1.6e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EER28876.1 - 0.00085 19.4 0.3 0.0074 16.3 0.2 2.3 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EER28876.1 - 0.0011 19.5 0.4 0.0062 17.0 0.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EER28876.1 - 0.0035 17.7 0.0 0.0078 16.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.21 EER28877.1 - 2.5e-44 151.4 16.2 3.8e-44 150.8 15.9 1.4 2 0 0 2 2 2 1 Cation efflux family Thiolase_N PF00108.23 EER28878.1 - 3.4e-92 308.5 2.8 4.6e-92 308.1 2.8 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EER28878.1 - 9.8e-37 125.3 0.3 9.8e-37 125.3 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EER28878.1 - 0.0018 17.9 1.9 0.0068 16.0 1.7 1.9 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EER28878.1 - 0.89 9.4 4.4 8.6 6.3 0.1 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 5_nucleotid_C PF02872.18 EER28879.1 - 1.1e-38 133.0 0.0 1.8e-38 132.2 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EER28879.1 - 1.5e-05 25.6 0.1 2.5e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3246 PF11596.8 EER28879.1 - 0.02 14.3 1.4 0.031 13.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) His_Phos_1 PF00300.22 EER28880.1 - 0.00049 19.9 3.7 2.6 7.7 0.1 4.0 2 2 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Kinesin PF00225.23 EER28881.1 - 2.6e-112 375.0 0.3 2.6e-112 375.0 0.3 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EER28881.1 - 4.6e-26 91.6 0.1 2e-25 89.5 0.1 2.1 1 0 0 1 1 1 1 Microtubule binding DUF1398 PF07166.11 EER28881.1 - 0.091 12.8 0.1 0.31 11.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) TFA2_Winged_2 PF18121.1 EER28881.1 - 0.16 11.7 1.1 1.4 8.6 0.2 3.0 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 CALCOCO1 PF07888.11 EER28881.1 - 1.5 7.6 60.0 0.01 14.8 31.7 2.4 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like UQ_con PF00179.26 EER28882.1 - 3.7e-52 175.7 0.0 4.2e-52 175.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER28882.1 - 0.00041 20.0 0.0 0.00046 19.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EER28882.1 - 0.074 13.3 0.0 0.14 12.5 0.0 1.4 1 1 0 1 1 1 0 RWD domain Pkinase PF00069.25 EER28883.1 - 2.2e-07 30.5 0.0 8.2e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain EMP70 PF02990.16 EER28884.1 - 7.6e-193 641.9 1.1 9.5e-193 641.6 1.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EF-hand_1 PF00036.32 EER28885.1 - 8.2e-26 87.6 10.1 3.1e-08 32.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EER28885.1 - 1.2e-24 84.1 2.7 3.3e-06 26.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EER28885.1 - 3.3e-24 85.1 1.8 5.8e-15 55.5 0.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EER28885.1 - 5.2e-18 63.7 7.7 4.3e-05 22.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EER28885.1 - 7.9e-15 54.4 11.5 4.8e-06 26.3 1.2 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EER28885.1 - 1.3e-08 34.7 4.2 0.0021 18.0 0.2 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EER28885.1 - 0.0009 19.5 0.2 0.023 15.0 0.1 2.5 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 EER28885.1 - 0.0064 16.3 0.7 2.3 8.2 0.0 3.4 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 EER28885.1 - 0.0088 16.4 0.4 0.81 10.0 0.2 2.9 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Rer1 PF03248.13 EER28886.1 - 0.011 15.5 0.2 0.021 14.5 0.2 1.5 1 0 0 1 1 1 0 Rer1 family DUF1772 PF08592.11 EER28886.1 - 0.23 11.8 14.3 0.35 11.2 3.9 3.0 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) UQ_con PF00179.26 EER28887.1 - 2.5e-43 147.1 0.0 2.8e-43 146.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CFEM PF05730.11 EER28888.1 - 4.9e-13 49.0 6.4 8.1e-13 48.3 6.4 1.3 1 0 0 1 1 1 1 CFEM domain Aminotran_1_2 PF00155.21 EER28889.1 - 8.4e-16 58.1 0.0 1.5e-08 34.2 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EER28889.1 - 0.008 14.8 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EER28889.1 - 0.0085 15.4 0.4 0.03 13.6 0.0 1.7 1 1 1 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Med4 PF10018.9 EER28891.1 - 6e-39 133.7 2.6 9.9e-39 133.0 2.6 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Folliculin PF11704.8 EER28891.1 - 0.25 11.2 1.6 1.6 8.5 1.6 2.1 1 1 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport HsbA PF12296.8 EER28891.1 - 1.7 9.1 14.4 0.2 12.1 1.6 2.9 3 0 0 3 3 3 0 Hydrophobic surface binding protein A MFS_1 PF07690.16 EER28892.1 - 1.1e-25 90.3 13.4 1.1e-25 90.3 13.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER28892.1 - 1.5e-11 43.8 0.9 1.5e-11 43.8 0.9 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EER28892.1 - 0.0014 17.1 1.9 0.0014 17.1 1.9 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EER28893.1 - 7.8e-27 94.1 26.6 7.8e-27 94.1 26.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER28893.1 - 0.0049 15.3 1.6 0.0092 14.4 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.7 EER28894.1 - 5.3e-09 35.8 0.5 1.6e-08 34.3 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER28894.1 - 2.2e-06 27.4 0.0 5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain Oxidored-like PF09791.9 EER28894.1 - 0.023 14.4 0.5 0.09 12.5 0.5 2.0 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal HTH_Tnp_Tc5 PF03221.16 EER28895.1 - 1.2e-15 57.3 0.0 3.1e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_ISL3 PF13542.6 EER28895.1 - 0.0043 16.4 0.1 0.0073 15.7 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_psq PF05225.16 EER28895.1 - 0.075 12.8 0.2 0.24 11.2 0.1 1.8 1 1 1 2 2 2 0 helix-turn-helix, Psq domain RabGAP-TBC PF00566.18 EER28896.1 - 1.4e-49 168.6 1.2 8.4e-49 166.1 0.0 2.7 2 1 1 3 3 3 1 Rab-GTPase-TBC domain PIN_8 PF18476.1 EER28896.1 - 0.0038 17.1 6.0 0.0038 17.1 6.0 2.6 2 1 1 3 3 3 1 PIN like domain ATPase_2 PF01637.18 EER28896.1 - 0.032 14.1 0.9 1.2 9.0 0.6 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NBD94 PF16830.5 EER28896.1 - 1.7 9.1 5.3 1.2 9.5 2.7 2.1 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH CENP-K PF11802.8 EER28896.1 - 5.8 6.4 19.9 0.56 9.7 6.3 2.4 1 1 1 2 2 2 0 Centromere-associated protein K DNA_topoisoIV PF00521.20 EER28897.1 - 8.4e-135 449.9 0.2 2.4e-134 448.5 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EER28897.1 - 1.9e-52 176.9 3.2 8e-52 174.9 3.2 2.2 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EER28897.1 - 1.5e-28 99.5 1.9 3.8e-28 98.1 1.9 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EER28897.1 - 7.5e-16 58.6 0.1 5.8e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EER28897.1 - 2.8e-07 30.7 0.2 3.5e-06 27.2 0.0 3.0 3 0 0 3 3 3 1 Toprim domain DUF3386 PF11866.8 EER28897.1 - 0.067 12.7 1.3 0.15 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3386) Reticulon PF02453.17 EER28900.1 - 2.3e-26 92.7 3.5 3e-26 92.3 3.5 1.2 1 0 0 1 1 1 1 Reticulon Cytochrome-c551 PF10643.9 EER28900.1 - 0.0069 16.0 0.1 0.0097 15.5 0.1 1.3 1 0 0 1 1 1 1 Photosystem P840 reaction-centre cytochrome c-551 Phage_holin_3_6 PF07332.11 EER28900.1 - 0.031 14.3 0.3 6.4 6.9 0.1 2.2 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Acyl-CoA_dh_1 PF00441.24 EER28901.1 - 5.2e-30 104.6 1.3 5.2e-30 104.6 1.3 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EER28901.1 - 2.6e-24 86.1 0.3 5.4e-24 85.0 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EER28901.1 - 1.3e-20 73.4 0.0 2.4e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EER28901.1 - 1.1e-14 54.9 3.8 2.1e-14 54.0 0.7 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain INCENP_ARK-bind PF03941.15 EER28902.1 - 1.8e-16 59.8 0.2 8.2e-16 57.7 0.1 2.3 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PDZ_1 PF12812.7 EER28903.1 - 6e-55 183.2 0.0 5.8e-36 122.4 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EER28903.1 - 7.6e-23 82.1 0.1 9.3e-21 75.3 0.0 2.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_6 PF17820.1 EER28903.1 - 6.8e-16 57.9 1.3 1.5e-07 31.1 0.6 4.5 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 EER28903.1 - 5.2e-13 49.1 0.2 0.00013 22.2 0.0 3.9 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 EER28903.1 - 3.8e-11 43.2 0.0 7.6e-05 23.0 0.0 3.7 3 0 0 3 3 3 3 PDZ domain Trypsin PF00089.26 EER28903.1 - 0.00017 21.5 0.0 0.00062 19.6 0.0 1.9 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EER28903.1 - 0.0087 16.0 0.0 3.4 7.7 0.1 4.0 4 0 0 4 4 4 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EER28903.1 - 0.051 13.3 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 EER28903.1 - 0.09 11.4 0.4 0.15 10.7 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 DUF31 PF01732.16 EER28903.1 - 0.16 11.5 0.2 0.24 10.9 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) SSXT PF05030.12 EER28904.1 - 1e-08 34.7 0.0 0.0017 18.0 0.0 2.8 2 0 0 2 2 2 2 SSXT protein (N-terminal region) Fungal_trans PF04082.18 EER28905.1 - 2.2e-13 49.9 3.9 4.3e-13 48.9 0.1 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28905.1 - 7.1e-05 22.8 11.0 0.00015 21.8 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_2 PF07719.17 EER28906.1 - 3.8e-11 42.2 4.8 0.013 15.6 0.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EER28906.1 - 7.7e-10 38.2 5.7 0.00047 19.9 0.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER28906.1 - 0.00021 21.3 2.7 0.28 11.5 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EER28906.1 - 0.0015 18.7 0.1 0.0035 17.5 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 EER28906.1 - 0.0038 17.7 0.5 0.0038 17.7 0.5 2.0 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_12 PF13424.6 EER28906.1 - 0.01 16.1 2.4 2.8 8.3 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EER28906.1 - 0.031 13.9 1.8 0.72 9.6 0.2 2.9 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 EER28906.1 - 0.064 13.8 0.8 0.064 13.8 0.8 2.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EER28906.1 - 0.29 11.6 1.0 2.3 8.8 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EER28906.1 - 1.6 9.7 5.7 1.4 10.0 0.3 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat NuDC PF16273.5 EER28907.1 - 0.065 13.8 1.6 0.19 12.3 1.6 1.9 1 1 0 1 1 1 0 Nuclear distribution C domain Herpes_UL25 PF01499.16 EER28907.1 - 0.083 11.4 2.3 0.11 11.1 2.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Spc7 PF08317.11 EER28907.1 - 0.24 10.3 6.4 0.31 9.9 6.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein peroxidase PF00141.23 EER28908.1 - 6.4e-44 150.3 0.0 9.4e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF1769 PF08588.10 EER28908.1 - 0.027 14.6 0.0 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1769) DUF4003 PF13170.6 EER28908.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Pyridoxal_deC PF00282.19 EER28910.1 - 7.2e-82 275.1 0.0 1e-81 274.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 EER28910.1 - 0.015 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family N2227 PF07942.12 EER28911.1 - 1.7e-52 178.3 0.0 2.6e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EER28911.1 - 0.00026 20.8 0.0 0.0014 18.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER28911.1 - 0.00056 20.6 0.0 0.002 18.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER28911.1 - 0.0011 19.6 0.0 0.0033 18.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CDC73_N PF16050.5 EER28911.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal Methyltransf_25 PF13649.6 EER28911.1 - 0.019 15.7 0.0 0.059 14.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain HAD_2 PF13419.6 EER28911.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF5441 PF17513.2 EER28912.1 - 0.018 14.8 0.4 0.038 13.7 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5441) Abhydrolase_1 PF00561.20 EER28913.1 - 1.7e-14 54.1 0.0 1e-13 51.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER28913.1 - 4.5e-07 30.7 1.6 5.5e-07 30.4 1.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EER28913.1 - 0.22 11.0 0.1 1.7 8.1 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family SBDS_C PF09377.10 EER28914.1 - 2e-43 147.1 0.0 2.8e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EER28914.1 - 1.6e-32 111.5 0.1 2.4e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_60s PF00428.19 EER28914.1 - 0.65 10.6 3.0 11 6.7 0.1 2.9 2 1 1 3 3 3 0 60s Acidic ribosomal protein Peptidase_S10 PF00450.22 EER28915.1 - 2.6e-131 438.9 0.1 3.2e-131 438.6 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EER28915.1 - 3.6e-12 46.9 0.0 7.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Ribosomal_S13 PF00416.22 EER28916.1 - 2.4e-56 189.6 4.3 2.8e-56 189.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EER28916.1 - 0.033 12.9 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 EER28916.1 - 0.057 13.7 0.4 0.21 11.9 0.1 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix motif p450 PF00067.22 EER28918.1 - 1.6e-52 178.9 0.0 1.9e-52 178.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDH-cyt PF16010.5 EER28920.1 - 3e-20 72.7 0.2 4.6e-20 72.1 0.2 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EER28920.1 - 2.9e-05 24.2 13.0 3.7e-05 23.9 11.4 2.0 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EER28920.1 - 0.0062 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 DOMON domain Yip1 PF04893.17 EER28920.1 - 2.5 7.8 15.4 6.7 6.4 15.4 1.6 1 0 0 1 1 1 0 Yip1 domain Abhydrolase_6 PF12697.7 EER28921.1 - 3.4e-05 24.6 0.6 3.4e-05 24.6 0.6 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER28921.1 - 6.6e-05 22.3 0.0 0.013 14.7 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EER28921.1 - 0.0038 17.1 0.0 0.0061 16.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EER28921.1 - 0.015 14.9 0.0 2 8.0 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.14 EER28921.1 - 0.18 11.1 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase DLH PF01738.18 EER28921.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Arrestin_N PF00339.29 EER28922.1 - 8.9e-08 32.3 0.0 5.6e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_N PF04425.12 EER28922.1 - 2.4e-07 29.9 0.4 8e-07 28.2 0.3 2.0 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 EER28922.1 - 0.007 15.8 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Bul1 C terminus Gly_transf_sug PF04488.15 EER28923.1 - 1.3e-19 70.7 0.1 2.7e-19 69.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EER28923.1 - 0.19 11.0 3.1 2.6 7.3 0.5 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain ERG4_ERG24 PF01222.17 EER28925.1 - 7.2e-146 486.3 18.0 9e-146 486.0 18.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Fungal_trans_2 PF11951.8 EER28926.1 - 6e-36 124.1 0.2 8.8e-36 123.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER28926.1 - 4.1e-10 39.6 5.4 9.2e-10 38.5 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_25 PF13481.6 EER28926.1 - 7.2 6.1 6.5 0.41 10.2 0.1 2.1 3 0 0 3 3 3 0 AAA domain IGPD PF00475.18 EER28929.1 - 1.3e-52 177.9 0.1 3e-52 176.8 0.1 1.5 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase LRR_6 PF13516.6 EER28930.1 - 0.0045 16.9 5.3 27 5.2 0.0 6.6 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.33 EER28930.1 - 0.052 14.1 0.7 1.2e+02 3.9 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat Pet127 PF08634.10 EER28931.1 - 4.8e-117 390.3 0.0 6.9e-117 389.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.19 EER28932.1 - 2e-84 282.2 0.0 4.9e-84 280.9 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EER28932.1 - 7.3e-35 119.6 0.2 4.7e-34 117.0 0.0 2.6 3 0 0 3 3 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EER28932.1 - 6.4e-31 107.6 0.0 1.7e-30 106.2 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EER28932.1 - 4.8e-27 94.0 0.7 1.4e-26 92.5 0.7 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EER28932.1 - 5.3e-14 52.7 4.5 6.7e-14 52.3 3.0 2.0 2 0 0 2 2 1 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EER28932.1 - 3.2e-06 26.8 0.0 6.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EER28932.1 - 7.6e-05 22.8 0.0 0.00026 21.1 0.0 1.9 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EER28932.1 - 0.00037 20.0 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EER28932.1 - 0.0022 17.6 0.0 0.0055 16.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EER28932.1 - 0.01 15.4 0.1 0.034 13.7 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.10 EER28932.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 EER28932.1 - 0.14 11.4 0.0 0.87 8.8 0.0 2.2 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Glyco_hydro_18 PF00704.28 EER28933.1 - 3.9e-84 283.0 6.9 4.5e-84 282.8 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Gpr1_Fun34_YaaH PF01184.19 EER28934.1 - 1.1e-56 191.7 16.0 1.6e-56 191.2 16.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family SQHop_cyclase_C PF13243.6 EER28935.1 - 4.8e-48 163.9 0.7 1.7e-46 158.8 0.4 2.4 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EER28935.1 - 5.5e-40 137.3 6.8 1.8e-35 122.4 3.3 3.5 2 1 0 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EER28935.1 - 1.1e-30 105.0 0.9 1.5e-09 37.4 0.0 4.0 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EER28935.1 - 7.8e-05 22.1 0.7 0.78 9.0 0.0 4.2 4 1 1 5 5 5 2 Pectic acid lyase TED_complement PF07678.14 EER28935.1 - 0.00016 20.8 0.0 0.005 15.9 0.0 2.9 2 1 1 3 3 3 1 A-macroglobulin TED domain Actin PF00022.19 EER28936.1 - 4.6e-151 503.0 0.0 1.7e-150 501.2 0.0 1.7 1 1 0 1 1 1 1 Actin Fes1 PF08609.10 EER28937.1 - 2.7e-27 95.5 6.2 2.7e-27 95.5 6.2 2.1 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.6 EER28937.1 - 1.9e-10 41.0 1.2 5.9e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EER28937.1 - 2.8e-08 33.3 0.4 0.0049 17.0 0.0 3.1 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.6 EER28937.1 - 1.2e-07 32.1 0.0 4.1e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 HEAT-like repeat Arm PF00514.23 EER28937.1 - 3.3e-06 27.0 0.0 0.13 12.4 0.0 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EER28937.1 - 3.8e-05 23.8 0.2 0.00011 22.3 0.1 1.8 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 EER28937.1 - 0.003 17.8 0.0 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 EER28937.1 - 0.0043 15.7 0.1 0.0071 15.0 0.1 1.3 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 EER28937.1 - 0.013 15.6 0.1 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 EER28937.1 - 0.067 13.2 0.1 0.3 11.1 0.0 1.9 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain UPF0220 PF05255.11 EER28938.1 - 2.9e-69 231.8 4.3 3.3e-69 231.7 4.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) AP3D1 PF06375.11 EER28939.1 - 0.0001 22.6 21.9 0.0001 22.6 21.9 1.0 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 DUF5327 PF17261.2 EER28939.1 - 0.0011 19.7 5.1 0.0012 19.5 5.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5327) BUD22 PF09073.10 EER28939.1 - 0.0011 18.4 16.8 0.0011 18.4 16.8 1.0 1 0 0 1 1 1 1 BUD22 Coilin_N PF15862.5 EER28939.1 - 0.043 13.6 18.3 0.06 13.1 18.3 1.2 1 0 0 1 1 1 0 Coilin N-terminus SID-1_RNA_chan PF13965.6 EER28939.1 - 0.087 11.2 3.2 0.085 11.3 3.2 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 EER28939.1 - 0.094 11.5 5.6 0.1 11.3 5.6 1.0 1 0 0 1 1 1 0 Presenilin Eapp_C PF10238.9 EER28939.1 - 0.096 12.8 9.6 0.11 12.6 9.6 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein HA2 PF04408.23 EER28939.1 - 0.1 12.9 5.5 0.12 12.7 5.5 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) CRA PF06589.11 EER28939.1 - 0.12 12.5 17.6 0.13 12.4 17.6 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF4820 PF16091.5 EER28939.1 - 0.12 11.7 6.6 0.11 11.8 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) PPL5 PF18168.1 EER28939.1 - 0.16 11.2 13.2 0.18 11.0 13.2 1.0 1 0 0 1 1 1 0 Prim-pol family 5 Kei1 PF08552.11 EER28939.1 - 0.17 11.8 2.4 0.17 11.7 2.4 1.0 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 V_ATPase_I PF01496.19 EER28939.1 - 0.17 9.7 8.1 0.18 9.7 8.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Connexin PF00029.19 EER28939.1 - 0.23 11.2 10.9 0.25 11.0 10.9 1.0 1 0 0 1 1 1 0 Connexin Otopetrin PF03189.13 EER28939.1 - 0.24 10.2 4.2 0.25 10.1 4.2 1.0 1 0 0 1 1 1 0 Otopetrin OATP PF03137.20 EER28939.1 - 0.25 9.6 5.0 0.24 9.7 5.0 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF1168 PF06658.12 EER28939.1 - 0.4 10.5 29.9 0.46 10.3 29.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) DUF4746 PF15928.5 EER28939.1 - 0.41 10.0 11.4 0.43 10.0 11.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFB6 PF17110.5 EER28939.1 - 0.48 10.2 7.3 0.53 10.0 7.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Rrn6 PF10214.9 EER28939.1 - 0.6 8.5 7.3 0.64 8.4 7.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CSRNP_N PF16019.5 EER28939.1 - 0.79 9.6 9.5 0.9 9.4 9.5 1.0 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus CPSF100_C PF13299.6 EER28939.1 - 0.83 9.8 11.1 0.88 9.7 11.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 EER28939.1 - 0.93 8.5 4.1 0.93 8.5 4.1 1.0 1 0 0 1 1 1 0 CLN3 protein Slu7 PF11708.8 EER28939.1 - 0.96 9.1 20.8 1.1 9.0 20.8 1.0 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor SpoIIP PF07454.11 EER28939.1 - 0.98 8.8 13.1 0.98 8.8 13.1 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FHIPEP PF00771.20 EER28939.1 - 1 7.7 3.0 0.91 7.9 3.0 1.0 1 0 0 1 1 1 0 FHIPEP family DDHD PF02862.17 EER28939.1 - 1.1 9.4 6.0 1.2 9.3 6.0 1.0 1 0 0 1 1 1 0 DDHD domain RabGAP-TBC PF00566.18 EER28939.1 - 1.2 8.8 8.8 1.3 8.6 8.8 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain TFIIF_alpha PF05793.12 EER28939.1 - 1.3 7.5 29.8 1.5 7.3 29.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GNAT_acetyltr_2 PF13718.6 EER28939.1 - 1.3 8.4 6.6 1.3 8.4 6.6 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Pox_Ag35 PF03286.14 EER28939.1 - 1.4 8.7 24.9 1.6 8.5 24.9 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF913 PF06025.12 EER28939.1 - 1.5 7.7 6.1 1.6 7.6 6.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Afi1 PF07792.12 EER28939.1 - 1.6 9.2 14.8 2 8.9 14.8 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF3537 PF12056.8 EER28939.1 - 1.7 7.4 4.2 1.9 7.2 4.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Folate_carrier PF01770.18 EER28939.1 - 1.9 7.1 4.6 1.7 7.3 4.6 1.0 1 0 0 1 1 1 0 Reduced folate carrier SR-25 PF10500.9 EER28939.1 - 2 8.0 31.8 2 8.0 31.8 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EIIBC-GUT_N PF03612.14 EER28939.1 - 2.2 8.0 10.2 2.4 7.9 10.2 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Serinc PF03348.15 EER28939.1 - 2.2 7.1 4.6 2.2 7.1 4.6 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ureide_permease PF07168.11 EER28939.1 - 2.3 6.9 7.2 2.6 6.7 7.2 1.0 1 0 0 1 1 1 0 Ureide permease DUF4666 PF15697.5 EER28939.1 - 2.3 8.9 8.9 3.4 8.4 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4666) ORC_WH_C PF18137.1 EER28939.1 - 2.4 8.2 15.2 2.7 8.0 15.2 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal AIF_C PF14721.6 EER28939.1 - 3.2 8.1 10.0 3.5 8.0 10.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3464 PF11947.8 EER28939.1 - 3.3 7.5 18.5 3.6 7.3 18.5 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Tom22 PF04281.13 EER28939.1 - 3.3 7.5 9.8 4 7.2 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 FAM176 PF14851.6 EER28939.1 - 3.6 7.2 14.2 5.2 6.7 14.2 1.3 1 1 0 1 1 1 0 FAM176 family Vfa1 PF08432.10 EER28939.1 - 3.6 7.9 26.3 4.4 7.6 26.3 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peroxin-13_N PF04088.13 EER28939.1 - 3.6 7.9 6.8 3.7 7.8 6.8 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Zip PF02535.22 EER28939.1 - 3.9 6.6 7.2 4.2 6.5 7.2 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter SspB PF04386.13 EER28939.1 - 3.9 7.3 10.9 4.4 7.2 10.9 1.1 1 0 0 1 1 1 0 Stringent starvation protein B Conotoxin PF02950.17 EER28939.1 - 4.4 8.4 9.3 15 6.7 9.3 1.8 1 1 0 1 1 1 0 Conotoxin Paramyxo_ncap PF00973.19 EER28939.1 - 4.5 6.1 8.7 4.5 6.1 8.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein GAGA_bind PF06217.12 EER28939.1 - 4.9 7.3 16.5 5.4 7.2 16.5 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family MAP17 PF15807.5 EER28939.1 - 5 7.4 15.2 5.8 7.2 15.2 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 INSIG PF07281.12 EER28939.1 - 5 6.7 4.3 3.8 7.1 3.5 1.3 1 1 0 1 1 1 0 Insulin-induced protein (INSIG) RNA_pol_3_Rpc31 PF11705.8 EER28939.1 - 5.2 7.3 22.1 5.6 7.2 22.1 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Rtf2 PF04641.12 EER28939.1 - 5.2 6.4 21.7 6.4 6.0 21.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Sec62 PF03839.16 EER28939.1 - 5.9 6.3 16.3 8.6 5.8 16.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF3987 PF13148.6 EER28939.1 - 6.2 5.7 13.8 6.7 5.6 13.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RPN2_C PF18004.1 EER28939.1 - 9.4 6.1 24.1 11 5.9 24.1 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Pkinase PF00069.25 EER28940.1 - 6.3e-28 97.9 0.0 8.5e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER28940.1 - 4.2e-24 85.2 0.0 5.8e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EER28940.1 - 3e-06 26.7 0.0 4.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EER28940.1 - 0.0062 15.9 0.0 0.015 14.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EER28940.1 - 0.017 14.7 0.4 1.1 8.8 0.1 2.3 1 1 1 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EER28940.1 - 0.018 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EER28940.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.8 EER28940.1 - 0.053 13.1 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 WaaY PF06176.11 EER28940.1 - 0.06 13.0 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) AP3D1 PF06375.11 EER28941.1 - 1.4e-06 28.6 5.4 1.4e-06 28.6 5.4 1.1 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 SR-25 PF10500.9 EER28941.1 - 4.5e-05 23.2 8.9 4.6e-05 23.2 8.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RMI1_N PF08585.12 EER28941.1 - 0.00037 20.3 0.1 0.00041 20.2 0.1 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Otopetrin PF03189.13 EER28941.1 - 0.013 14.4 0.1 0.017 14.0 0.1 1.2 1 0 0 1 1 1 0 Otopetrin Connexin PF00029.19 EER28941.1 - 0.015 15.1 0.4 0.015 15.1 0.4 1.2 1 0 0 1 1 1 0 Connexin PPL5 PF18168.1 EER28941.1 - 0.41 9.9 6.0 0.55 9.5 6.0 1.3 1 0 0 1 1 1 0 Prim-pol family 5 FAM176 PF14851.6 EER28941.1 - 2.6 7.7 4.6 3.4 7.3 4.6 1.2 1 0 0 1 1 1 0 FAM176 family DUF3984 PF13136.6 EER28941.1 - 3.6 6.9 8.5 7 6.0 8.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3984) Peptidase_S49_N PF08496.10 EER28941.1 - 4.9 7.2 14.8 6.6 6.8 14.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtf2 PF04641.12 EER28942.1 - 1.4e-05 24.6 1.8 1.4e-05 24.6 1.8 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Histone PF00125.24 EER28942.1 - 0.00011 22.6 14.0 0.00017 21.9 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 SAPS PF04499.15 EER28942.1 - 0.0002 20.3 1.0 0.0002 20.3 1.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein BUD22 PF09073.10 EER28942.1 - 0.0029 17.0 26.9 0.0037 16.7 26.9 1.1 1 0 0 1 1 1 1 BUD22 Connexin PF00029.19 EER28942.1 - 0.024 14.4 6.9 0.04 13.7 6.9 1.3 1 0 0 1 1 1 0 Connexin U1snRNP70_N PF12220.8 EER28942.1 - 0.03 14.9 10.2 0.047 14.3 10.2 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4746 PF15928.5 EER28942.1 - 0.04 13.4 14.1 0.053 12.9 14.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Cwf_Cwc_15 PF04889.12 EER28942.1 - 0.042 13.6 28.2 0.053 13.3 28.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.13 EER28942.1 - 0.043 13.8 14.8 0.046 13.7 14.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 EER28942.1 - 0.051 12.6 1.1 0.072 12.1 1.1 1.2 1 0 0 1 1 1 0 CLN3 protein PPL5 PF18168.1 EER28942.1 - 0.053 12.8 11.9 0.078 12.3 11.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Serinc PF03348.15 EER28942.1 - 0.079 11.9 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 EER28942.1 - 0.084 11.3 2.2 0.1 11.0 2.2 1.2 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 ASC PF00858.24 EER28942.1 - 0.09 11.7 0.1 0.088 11.8 0.1 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel DUF913 PF06025.12 EER28942.1 - 0.091 11.7 5.8 0.11 11.4 5.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FYDLN_acid PF09538.10 EER28942.1 - 0.096 13.4 25.7 0.16 12.6 25.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Coilin_N PF15862.5 EER28942.1 - 0.2 11.4 18.6 0.3 10.9 18.6 1.2 1 0 0 1 1 1 0 Coilin N-terminus RNA_pol_Rpc4 PF05132.14 EER28942.1 - 0.26 11.7 11.1 0.35 11.3 11.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 CPSF100_C PF13299.6 EER28942.1 - 0.28 11.3 13.9 0.46 10.6 13.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DDHD PF02862.17 EER28942.1 - 0.3 11.2 3.9 0.37 10.9 3.9 1.1 1 0 0 1 1 1 0 DDHD domain CNDH2_C PF16858.5 EER28942.1 - 0.31 10.9 16.9 0.41 10.5 16.9 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term VIR_N PF15912.5 EER28942.1 - 0.33 10.5 11.5 0.45 10.1 11.5 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal SspB PF04386.13 EER28942.1 - 0.8 9.6 13.3 1.1 9.2 12.5 1.6 2 0 0 2 2 1 0 Stringent starvation protein B RNA_pol_3_Rpc31 PF11705.8 EER28942.1 - 0.98 9.6 33.4 1.4 9.1 33.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RPOL_N PF14700.6 EER28942.1 - 0.99 8.7 9.1 1.3 8.3 9.1 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF3987 PF13148.6 EER28942.1 - 1.2 8.0 5.4 1.6 7.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FGF-BP1 PF06473.12 EER28942.1 - 1.9 8.2 14.6 2.6 7.8 14.6 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF4820 PF16091.5 EER28942.1 - 2.2 7.6 11.4 3.1 7.1 11.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CSRNP_N PF16019.5 EER28942.1 - 2.5 8.0 15.1 3.7 7.4 15.1 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Slu7 PF11708.8 EER28942.1 - 3.5 7.3 28.1 4.5 6.9 28.1 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF1168 PF06658.12 EER28942.1 - 3.5 7.4 31.4 4.6 7.1 31.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Nop14 PF04147.12 EER28942.1 - 3.9 5.6 29.5 4.9 5.2 29.5 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 EER28942.1 - 4.2 7.1 17.6 5.5 6.7 17.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 EER28942.1 - 4.5 6.7 16.5 5.5 6.4 16.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2076 PF09849.9 EER28942.1 - 4.9 7.1 15.3 6.6 6.7 15.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Astro_capsid_p PF12226.8 EER28942.1 - 5 6.2 22.0 6.3 5.9 22.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Afi1 PF07792.12 EER28942.1 - 5.4 7.5 21.8 7.3 7.1 21.8 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EIIBC-GUT_N PF03612.14 EER28942.1 - 5.4 6.7 9.2 8.2 6.1 9.2 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Pox_Ag35 PF03286.14 EER28942.1 - 8.3 6.1 25.4 14 5.5 25.4 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Eapp_C PF10238.9 EER28942.1 - 9.2 6.3 13.9 24 5.0 13.9 1.7 1 0 0 1 1 1 0 E2F-associated phosphoprotein Sld7_C PF18596.1 EER28943.1 - 2.4e-13 50.0 0.6 8.8e-13 48.2 0.6 2.0 1 1 0 1 1 1 1 Sld7 C-terminal domain Vps55 PF04133.14 EER28944.1 - 8.8e-43 145.0 7.3 9.9e-43 144.8 7.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.26 EER28945.1 - 5.3e-52 176.1 0.1 6.7e-52 175.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EER28945.1 - 2.6e-12 46.2 0.3 5e-12 45.3 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 EER28945.1 - 0.057 13.3 0.7 30 4.6 0.1 3.2 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK Lysine_decarbox PF03641.14 EER28946.1 - 1.2e-30 106.3 0.0 2e-30 105.6 0.0 1.5 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EER28946.1 - 0.0045 16.6 1.3 0.085 12.4 0.2 2.7 1 1 2 3 3 3 1 SLOG cluster4 family LSDAT_prok PF18171.1 EER28946.1 - 0.12 11.6 0.1 0.26 10.5 0.1 1.6 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Med6 PF04934.14 EER28947.1 - 1.9e-38 131.3 0.0 2.7e-38 130.8 0.0 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component RdRP PF05183.12 EER28948.1 - 8.8e-183 609.1 0.0 1.4e-182 608.4 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase Chorismate_bind PF00425.18 EER28949.1 - 5.4e-18 65.5 0.1 3.1e-17 63.0 0.1 2.0 1 1 0 1 1 1 1 chorismate binding enzyme Herpes_LMP1 PF05297.11 EER28949.1 - 0.1 11.8 0.2 0.17 11.0 0.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) CtIP_N PF10482.9 EER28949.1 - 0.26 11.3 3.1 11 6.1 0.9 2.5 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Trypan_PARP PF05887.11 EER28949.1 - 0.89 9.5 9.1 0.81 9.7 5.4 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) HisKA PF00512.25 EER28950.1 - 0.037 14.1 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF3684 PF12449.8 EER28951.1 - 0 1397.5 0.0 0 1397.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EER28951.1 - 0.00065 19.5 0.0 0.0022 17.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAPPC9-Trs120 PF08626.11 EER28952.1 - 0 1460.4 0.0 0 1460.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Abhydrolase_1 PF00561.20 EER28953.1 - 1.7e-16 60.7 0.0 4e-16 59.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER28953.1 - 5.3e-11 42.3 0.0 2.9e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EER28953.1 - 9.8e-05 23.1 0.0 0.0002 22.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family SR-25 PF10500.9 EER28954.1 - 0.001 18.7 21.9 0.001 18.7 21.9 2.1 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein Complex1_LYR_2 PF13233.6 EER28955.1 - 1.2e-06 29.1 0.6 1.8e-06 28.6 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EER28955.1 - 1.3e-05 25.1 0.4 2.5e-05 24.2 0.4 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) RNA_pol_L_2 PF13656.6 EER28956.1 - 1.6e-33 114.3 0.0 2.3e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EER28956.1 - 1e-14 53.7 0.0 1.4e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_M22 PF00814.25 EER28957.1 - 3.7e-85 285.9 0.0 5.1e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EER28957.1 - 0.017 14.8 0.0 0.37 10.4 0.0 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus SET PF00856.28 EER28958.1 - 6.4e-16 59.2 0.0 1.6e-15 57.9 0.0 1.7 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EER28958.1 - 2.4e-14 54.2 2.4 3e-14 53.8 1.0 1.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding EPL1 PF10513.9 EER28959.1 - 3.2e-21 76.4 0.4 3.2e-21 76.4 0.4 2.3 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.32 EER28960.1 - 3.8e-25 85.5 12.9 3.2e-07 29.4 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EER28960.1 - 8.3e-21 74.2 15.9 7.6e-13 48.7 1.4 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EER28960.1 - 3e-19 67.2 5.7 8.4e-05 22.2 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EER28960.1 - 4.6e-17 60.7 11.9 8.2e-07 28.2 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EER28960.1 - 4.8e-12 45.5 11.3 0.00022 21.0 0.5 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EER28960.1 - 3.5e-06 27.3 0.2 0.0091 16.3 0.0 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EER28960.1 - 8.4e-06 25.7 10.0 0.024 14.6 0.2 3.9 1 1 3 4 4 4 4 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EER28960.1 - 0.013 15.7 0.5 0.14 12.4 0.5 2.6 1 1 0 1 1 1 0 Dockerin type I domain EF-hand_9 PF14658.6 EER28960.1 - 0.09 13.1 0.0 2 8.8 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain RP-C_C PF11800.8 EER28961.1 - 0.037 14.1 1.1 0.14 12.2 0.2 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region Ribosomal_S9 PF00380.19 EER28963.1 - 9.3e-42 142.4 0.2 1.3e-41 141.9 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 EER28964.1 - 1.2e-47 160.3 0.1 2.6e-47 159.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EER28964.1 - 3.3e-13 49.7 0.1 1.6e-12 47.5 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EER28964.1 - 1.5e-11 44.5 0.0 6.4e-11 42.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EER28964.1 - 6.8e-09 35.6 0.0 2e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EER28964.1 - 6.2e-08 33.0 0.0 1.3e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EER28964.1 - 2.3e-05 24.5 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EER28964.1 - 0.0052 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.18 EER28965.1 - 5.7e-25 87.9 0.1 8.7e-25 87.3 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Peptidase_S49_N PF08496.10 EER28965.1 - 1.2 9.1 3.7 2.2 8.3 3.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RRP36 PF06102.12 EER28966.1 - 1.9e-48 164.6 19.5 1.9e-48 164.6 19.5 1.8 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF2681 PF10883.8 EER28966.1 - 6.6 7.2 8.6 0.28 11.6 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) NAD_binding_2 PF03446.15 EER28968.1 - 1.8e-23 83.4 0.1 4.9e-23 82.0 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EER28968.1 - 2.2e-11 44.0 0.0 4.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EER28968.1 - 0.025 14.6 0.1 0.061 13.4 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EER28968.1 - 0.046 13.6 0.1 0.099 12.5 0.1 1.6 2 0 0 2 2 2 0 NAD(P)H-binding UDPG_MGDP_dh PF00984.19 EER28968.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain DUF1757 PF08560.10 EER28970.1 - 5e-07 29.9 0.0 6.4e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) HisKA_4TM PF16926.5 EER28970.1 - 0.031 13.9 0.3 0.031 13.9 0.3 1.6 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase TetR_C_14 PF17754.1 EER28970.1 - 0.086 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 MftR C-terminal domain Abhydrolase_1 PF00561.20 EER28971.1 - 3.9e-17 62.8 0.0 1.9e-11 44.1 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER28971.1 - 2.4e-13 49.9 0.0 4.1e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EER28971.1 - 2.2e-11 44.8 0.0 2.7e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EER28971.1 - 0.001 18.9 0.0 0.025 14.4 0.0 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 EER28971.1 - 0.007 15.1 0.0 0.032 13.0 0.0 1.8 1 1 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 EER28971.1 - 0.027 14.0 0.0 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family AMPK1_CBM PF16561.5 EER28972.1 - 1.5e-28 98.8 0.0 2.5e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EER28972.1 - 8.7e-26 90.0 1.2 2.5e-25 88.5 1.2 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Mannosyl_trans3 PF11051.8 EER28973.1 - 5.3e-62 209.7 0.1 1.9e-34 119.3 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative ABC1 PF03109.16 EER28974.1 - 1.9e-32 111.9 0.0 4.2e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family UreF PF01730.16 EER28975.1 - 1.5e-21 77.4 0.4 2.5e-21 76.7 0.4 1.3 1 0 0 1 1 1 1 UreF BRE1 PF08647.11 EER28976.1 - 1.3e-28 98.9 13.4 1.3e-28 98.9 13.4 6.8 5 3 1 6 6 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EER28976.1 - 8.4e-09 35.2 7.9 1.5e-08 34.4 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER28976.1 - 2.4e-08 33.7 8.4 4.3e-08 32.9 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER28976.1 - 1.2e-07 31.5 10.3 2.1e-07 30.7 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EER28976.1 - 1.3e-07 31.4 6.4 2.2e-07 30.6 6.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EER28976.1 - 3e-07 30.3 5.4 5.9e-07 29.4 5.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EER28976.1 - 1.8e-06 28.1 9.5 3.2e-06 27.4 9.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EER28976.1 - 4.9e-05 23.2 10.2 8.6e-05 22.4 10.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF745 PF05335.13 EER28976.1 - 0.00012 21.9 8.6 0.00012 21.9 8.6 5.6 3 2 3 6 6 5 1 Protein of unknown function (DUF745) PspA_IM30 PF04012.12 EER28976.1 - 0.0018 17.9 11.1 0.0018 17.9 11.1 6.1 2 1 3 5 5 3 1 PspA/IM30 family zf-rbx1 PF12678.7 EER28976.1 - 0.0038 17.5 6.2 0.026 14.8 6.2 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain DUF1272 PF06906.11 EER28976.1 - 0.015 15.3 5.6 0.034 14.2 5.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) JIP_LZII PF16471.5 EER28976.1 - 0.017 15.2 2.7 0.017 15.2 2.7 7.4 6 1 1 7 7 7 0 JNK-interacting protein leucine zipper II zf-RING_10 PF16685.5 EER28976.1 - 0.031 14.4 6.1 0.077 13.1 6.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 PRP1_N PF06424.12 EER28976.1 - 0.038 14.4 0.8 0.038 14.4 0.8 5.1 3 1 1 5 5 3 0 PRP1 splicing factor, N-terminal zf-C3HC4_4 PF15227.6 EER28976.1 - 0.04 14.1 6.4 0.079 13.1 6.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EER28976.1 - 0.061 13.1 7.0 0.26 11.1 7.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1192 PF06698.11 EER28976.1 - 0.062 13.4 0.5 0.062 13.4 0.5 7.1 7 1 2 9 9 8 0 Protein of unknown function (DUF1192) CENP-F_leu_zip PF10473.9 EER28976.1 - 0.11 12.5 82.5 0.039 14.0 16.7 6.9 3 1 4 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-UDP PF14569.6 EER28976.1 - 0.28 11.3 4.0 0.77 9.9 4.0 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger DZR PF12773.7 EER28976.1 - 1.2 9.2 6.9 2.5 8.2 6.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 EER28976.1 - 2.7 7.9 5.9 7.5 6.5 5.9 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 EER28976.1 - 6.6 7.0 11.0 1.1e+02 3.0 0.4 2.5 1 1 1 2 2 2 0 FYVE zinc finger Shugoshin_N PF07558.11 EER28976.1 - 7.3 6.5 16.7 24 4.9 0.5 5.9 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region APC_N_CC PF16689.5 EER28976.1 - 8.9 6.5 19.0 0.35 11.0 2.8 5.1 3 1 1 4 4 4 0 Coiled-coil N-terminus of APC, dimerisation domain Myb_DNA-bind_7 PF15963.5 EER28977.1 - 1.8e-27 95.0 0.1 1.8e-27 95.0 0.1 2.3 2 1 0 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EER28977.1 - 8.6e-07 29.1 0.6 1.9e-06 28.0 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain SARAF PF06682.12 EER28978.1 - 1.4e-84 284.6 9.1 6.7e-83 279.1 9.1 2.0 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis BTB_2 PF02214.22 EER28979.1 - 9.6e-06 25.9 0.0 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EER28979.1 - 3.7e-05 23.9 0.0 5.9e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain MMM1 PF10296.9 EER28980.1 - 1.8e-135 451.3 0.0 2.3e-135 450.9 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 EVI2A PF05399.11 EER28980.1 - 2.2 7.8 5.7 0.26 10.8 0.1 2.1 2 1 1 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) ARD PF03079.14 EER28981.1 - 3e-45 154.2 0.1 3.6e-45 154.0 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EER28981.1 - 2.1e-09 36.9 0.2 3.5e-09 36.3 0.2 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EER28981.1 - 0.00024 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 EER28981.1 - 0.0089 15.7 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EER28981.1 - 0.051 13.2 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Cupin GIDA PF01134.22 EER28982.1 - 2.7e-154 514.0 0.0 3.4e-154 513.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EER28982.1 - 1.5e-65 221.3 0.0 2.3e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EER28982.1 - 1.7e-06 27.7 0.5 2.7e-06 27.0 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER28982.1 - 4.3e-06 26.2 0.2 8.3e-06 25.2 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EER28982.1 - 0.00095 18.3 2.3 0.00095 18.3 2.3 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EER28982.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EER28982.1 - 0.029 13.1 0.6 0.23 10.1 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 EER28982.1 - 0.13 11.8 1.8 8.4 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EER28982.1 - 0.27 10.1 0.3 8.3 5.1 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 EER28983.1 - 7.2e-40 137.0 29.7 2.5e-39 135.2 29.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EER28983.1 - 1.1e-19 70.3 10.8 1.4e-19 69.9 10.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER28983.1 - 1.3e-16 60.6 12.3 1.3e-16 60.6 12.3 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EER28983.1 - 0.00091 17.6 1.7 0.0018 16.6 1.7 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family CDP-OH_P_transf PF01066.21 EER28984.1 - 1.5e-15 57.7 1.1 1.5e-15 57.7 1.1 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase APH PF01636.23 EER28985.1 - 1.9e-09 37.8 0.0 3.1e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EER28985.1 - 0.057 12.7 0.0 0.077 12.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.20 EER28985.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EER28985.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1679 PF07914.11 EER28985.1 - 0.23 10.2 0.0 0.36 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HNH_2 PF13391.6 EER28986.1 - 1.2e-17 63.8 0.5 2.7e-17 62.7 0.2 1.8 2 0 0 2 2 2 1 HNH endonuclease Gti1_Pac2 PF09729.9 EER28987.1 - 2e-63 213.7 0.0 2.5e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family Tyr-DNA_phospho PF06087.12 EER28988.1 - 1.5e-69 235.0 0.0 3e-54 184.6 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 EER28988.1 - 0.00045 19.9 0.2 0.00045 19.9 0.2 3.4 3 0 0 3 3 3 1 Ubiquitin interaction motif PLDc_2 PF13091.6 EER28988.1 - 0.0059 16.5 0.1 0.021 14.7 0.0 1.9 2 0 0 2 2 2 1 PLD-like domain Pkinase PF00069.25 EER28990.1 - 5.2e-27 94.9 0.0 1.6e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER28990.1 - 7.7e-12 45.0 0.0 8.2e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PD40 PF07676.12 EER28990.1 - 0.075 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Myb_DNA-binding PF00249.31 EER28991.1 - 0.00041 20.5 0.2 0.00081 19.5 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain NAD_binding_8 PF13450.6 EER28992.1 - 7.8e-13 48.5 0.1 2.1e-12 47.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER28992.1 - 8.5e-10 38.7 0.0 6.2e-07 29.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER28992.1 - 9e-08 31.7 0.1 5.1e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EER28992.1 - 1.6e-07 31.0 0.0 0.00014 21.3 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EER28992.1 - 1.3e-05 24.2 0.9 6.9e-05 21.7 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EER28992.1 - 1.3e-05 24.5 1.4 2.1e-05 23.8 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EER28992.1 - 7.7e-05 22.1 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EER28992.1 - 0.00021 21.8 0.2 0.26 11.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EER28992.1 - 0.00054 19.3 0.4 0.0016 17.8 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EER28992.1 - 0.00071 19.6 0.2 0.0032 17.5 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EER28992.1 - 0.0021 17.5 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EER28992.1 - 0.0035 16.3 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EER28992.1 - 0.061 12.4 0.1 0.091 11.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 EER28992.1 - 0.093 12.0 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EER28992.1 - 0.12 12.0 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EER28992.1 - 0.16 11.0 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EER28992.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EER28993.1 - 9e-31 106.8 0.0 1.2e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER28993.1 - 1.5e-20 73.8 0.0 1.9e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER28993.1 - 6.4e-11 42.5 0.0 9.3e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EER28993.1 - 1e-06 28.4 0.1 1.9e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EER28993.1 - 0.00035 19.8 0.0 0.00069 18.8 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EER28993.1 - 0.0014 17.9 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EER28993.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 EER28993.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding 3Beta_HSD PF01073.19 EER28993.1 - 0.067 12.2 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EER28993.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sec1 PF00995.23 EER28994.1 - 7.8e-135 451.3 0.3 9.2e-135 451.1 0.3 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.13 EER28994.1 - 0.041 13.8 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family L27 PF02828.16 EER28994.1 - 0.11 12.2 0.2 0.33 10.7 0.2 1.8 1 0 0 1 1 1 0 L27 domain MBOAT PF03062.19 EER28995.1 - 8.3e-55 186.5 4.7 1.6e-54 185.5 4.7 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family AT_hook PF02178.19 EER28996.1 - 8 6.7 6.1 2.4 8.3 0.3 2.8 2 0 0 2 2 2 0 AT hook motif FAD_binding_4 PF01565.23 EER28997.1 - 6.8e-30 103.6 0.5 1.2e-29 102.9 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EER28997.1 - 0.0028 17.7 0.1 0.0055 16.8 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_2_C PF02836.17 EER28997.1 - 0.21 10.7 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain Na_Ca_ex PF01699.24 EER28998.1 - 0.0012 18.8 1.7 0.0012 18.8 1.7 3.0 2 1 1 3 3 3 1 Sodium/calcium exchanger protein GDE_N PF12439.8 EER28998.1 - 0.16 11.4 0.4 0.25 10.8 0.4 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal CPBP PF02517.16 EER28999.1 - 1.6e-13 50.9 14.9 1.6e-13 50.9 14.9 2.7 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease Suc_Fer-like PF06999.12 EER29000.1 - 4.7e-59 199.5 0.0 5.6e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF4873 PF16170.5 EER29000.1 - 0.15 12.3 0.1 5.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4873) tRNA-synt_1 PF00133.22 EER29001.1 - 4.2e-53 180.5 0.0 1.2e-35 122.9 0.3 6.2 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EER29001.1 - 2e-38 131.8 0.0 3.4e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EER29001.1 - 6.8e-31 107.4 0.0 1.2e-22 80.3 0.0 4.2 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EER29001.1 - 9.2e-17 61.4 0.0 1.6e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EER29001.1 - 0.00068 19.1 0.0 0.036 13.4 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain 2-Hacid_dh_C PF02826.19 EER29003.1 - 1.4e-49 167.9 0.0 2.1e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EER29003.1 - 1.1e-15 57.4 0.0 1.6e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GH115_C PF17829.1 EER29004.1 - 0.056 13.3 0.0 0.088 12.6 0.0 1.2 1 0 0 1 1 1 0 Gylcosyl hydrolase family 115 C-terminal domain PIRT PF15099.6 EER29005.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family FH2 PF02181.23 EER29006.1 - 5.3e-84 282.5 4.4 5.3e-84 282.5 4.4 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EER29006.1 - 5.5e-70 234.8 0.3 2.9e-69 232.4 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EER29006.1 - 1.4e-50 171.7 6.0 3.5e-50 170.3 0.3 3.2 2 1 1 3 3 3 2 Diaphanous FH3 Domain FA_hydroxylase PF04116.13 EER29008.1 - 4.7e-22 78.8 15.8 4.7e-22 78.8 15.8 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 EER29009.1 - 5.5e-28 97.9 29.8 5.5e-28 97.9 29.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EER29009.1 - 0.19 10.0 7.8 1.1 7.5 7.8 2.1 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family cobW PF02492.19 EER29010.1 - 1.8e-48 164.5 3.5 1.2e-36 125.9 0.6 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EER29010.1 - 2.7e-20 72.1 0.2 4.1e-15 55.5 0.0 2.9 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 EER29010.1 - 0.0082 16.0 0.2 0.022 14.7 0.2 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.6 EER29010.1 - 0.017 15.5 1.9 0.035 14.5 0.4 2.4 2 1 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 EER29010.1 - 0.046 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EER29010.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EER29010.1 - 0.18 11.6 0.1 0.44 10.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4637 PF15470.6 EER29010.1 - 9.9 5.9 10.8 0.83 9.4 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) TrmE_N PF10396.9 EER29011.1 - 1.2e-36 125.5 0.0 2.8e-36 124.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EER29011.1 - 1.8e-28 100.2 0.0 5.1e-28 98.6 0.0 1.7 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EER29011.1 - 8.2e-18 64.6 0.0 1.5e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EER29011.1 - 9.6e-06 25.8 0.0 2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EER29011.1 - 4.1e-05 23.1 0.0 0.00036 20.1 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EER29011.1 - 0.00012 21.7 0.1 0.021 14.4 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EER29011.1 - 0.021 14.6 0.2 0.049 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EER29011.1 - 0.068 13.4 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EER29011.1 - 0.087 12.7 0.4 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 EER29011.1 - 0.17 11.0 0.4 1.2 8.2 0.0 2.1 2 1 0 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 EER29011.1 - 0.2 12.2 0.1 0.2 12.2 0.1 2.1 2 1 0 2 2 2 0 ABC transporter Aconitase PF00330.20 EER29012.1 - 1.6e-113 380.2 0.2 1.2e-112 377.3 0.2 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EER29012.1 - 9.3e-25 87.5 0.0 1.9e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF5068 PF16781.5 EER29012.1 - 0.041 13.6 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5068) MCM PF00493.23 EER29012.1 - 0.19 10.8 0.2 0.32 10.0 0.2 1.3 1 0 0 1 1 1 0 MCM P-loop domain Aminotran_5 PF00266.19 EER29013.1 - 5.2e-30 104.6 0.0 7.8e-20 71.1 0.0 2.1 1 1 0 2 2 2 2 Aminotransferase class-V NAD_binding_1 PF00175.21 EER29014.1 - 1.6e-06 28.7 0.0 4.6e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EER29014.1 - 3.5e-06 27.3 0.0 1.8e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EER29014.1 - 0.041 14.0 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain UCR_Fe-S_N PF10399.9 EER29014.1 - 0.1 12.0 0.0 0.34 10.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal AA_permease_2 PF13520.6 EER29015.1 - 4.8e-63 213.5 43.7 6.3e-63 213.1 43.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER29015.1 - 1.1e-23 83.6 28.7 1.1e-23 83.6 28.7 2.0 2 0 0 2 2 2 1 Amino acid permease Methyltransf_31 PF13847.6 EER29017.1 - 7.8e-07 29.0 0.0 2.3e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EER29017.1 - 9e-07 28.6 0.0 0.00029 20.4 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase small domain PrmC_N PF17827.1 EER29017.1 - 7.4e-06 26.5 4.5 4e-05 24.1 0.2 3.2 3 1 0 3 3 3 1 PrmC N-terminal domain Methyltransf_25 PF13649.6 EER29017.1 - 9.1e-05 23.1 0.0 0.00022 21.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 EER29017.1 - 0.00083 18.9 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 RRNA methyltransferase AviRa Methyltransf_10 PF05971.12 EER29017.1 - 0.002 17.5 0.0 0.036 13.4 0.0 2.1 2 0 0 2 2 2 1 RNA methyltransferase Methyltransf_23 PF13489.6 EER29017.1 - 0.016 15.1 0.2 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EER29017.1 - 0.019 15.7 0.0 0.053 14.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EER29017.1 - 0.019 14.4 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EER29017.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 EER29017.1 - 0.071 12.8 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Asp PF00026.23 EER29018.1 - 3e-68 230.6 0.0 4e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EER29018.1 - 7e-15 55.7 0.6 4.1e-11 43.4 0.4 3.3 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EER29018.1 - 6.4e-06 26.7 0.0 0.25 12.0 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EER29018.1 - 0.0048 16.7 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EER29018.1 - 0.0084 16.6 0.0 4.3 8.0 0.0 3.5 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease GPR_Gpa2_C PF11970.8 EER29019.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.0 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DNA_pol3_delta2 PF13177.6 EER29020.1 - 3.2e-12 46.5 0.0 3.5e-09 36.7 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EER29020.1 - 1.5e-10 41.6 0.0 2.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EER29020.1 - 4.6e-07 29.9 0.0 8.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EER29020.1 - 3e-06 27.7 0.0 0.00016 22.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EER29020.1 - 9.1e-06 25.5 0.0 2.2e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 EER29020.1 - 6.2e-05 22.8 0.0 9.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.13 EER29020.1 - 0.00031 20.6 0.0 0.00042 20.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EER29020.1 - 0.00047 20.4 0.1 0.53 10.6 0.1 2.3 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EER29020.1 - 0.0017 17.8 0.0 0.021 14.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EER29020.1 - 0.0019 18.0 0.0 0.0046 16.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EER29020.1 - 0.0052 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EER29020.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 EER29020.1 - 0.0063 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EER29020.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EER29020.1 - 0.013 15.0 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DEAD PF00270.29 EER29020.1 - 0.014 15.2 0.1 0.54 10.0 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase TniB PF05621.11 EER29020.1 - 0.015 14.7 0.0 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_assoc_2 PF16193.5 EER29020.1 - 0.019 15.3 0.0 0.049 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain MeaB PF03308.16 EER29020.1 - 0.025 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EER29020.1 - 0.027 14.1 0.2 0.99 8.9 0.0 2.8 1 1 2 3 3 3 0 AAA domain AAA_19 PF13245.6 EER29020.1 - 0.044 14.1 0.2 0.6 10.4 0.1 2.3 1 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EER29020.1 - 0.045 13.7 0.2 0.088 12.7 0.2 1.6 1 1 0 1 1 1 0 NTPase AAA_5 PF07728.14 EER29020.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rep_fac_C PF08542.11 EER29020.1 - 0.1 13.0 0.1 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain AAA_18 PF13238.6 EER29020.1 - 0.16 12.5 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain His_Phos_2 PF00328.22 EER29021.1 - 1.8e-05 24.3 0.0 0.04 13.3 0.0 2.2 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Polysacc_deac_1 PF01522.21 EER29022.1 - 3.9e-19 68.7 0.0 8.9e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EER29022.1 - 3.7e-07 30.0 0.3 6.9e-06 25.9 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 EER29022.1 - 0.13 10.5 0.0 0.18 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Amidase PF01425.21 EER29023.1 - 5.9e-104 348.5 0.0 7.8e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF410 PF04190.13 EER29025.1 - 8.4e-87 291.2 0.0 1e-86 290.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) RAI1 PF08652.11 EER29026.1 - 3.1e-30 104.1 0.0 6.4e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.17 EER29027.1 - 6.8e-62 209.3 0.2 1.1e-61 208.6 0.2 1.3 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 EER29027.1 - 1.3e-07 31.9 0.0 0.047 13.8 0.0 3.6 1 1 0 2 2 2 2 AAA domain zf-met PF12874.7 EER29027.1 - 0.00064 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type IPT PF01745.16 EER29027.1 - 0.0032 16.9 0.0 0.011 15.1 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase CTU2 PF10288.9 EER29027.1 - 0.0069 16.6 0.2 0.016 15.4 0.2 1.6 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 zf-C2H2_2 PF12756.7 EER29027.1 - 0.024 14.9 1.2 0.038 14.3 0.4 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EER29027.1 - 0.1 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding AAA_18 PF13238.6 EER29027.1 - 0.2 12.2 1.5 1.6 9.3 0.3 3.0 1 1 3 4 4 4 0 AAA domain DUF465 PF04325.13 EER29027.1 - 6.7 6.8 6.5 7.4 6.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF465) ABC_tran PF00005.27 EER29028.1 - 2.7e-16 60.3 0.2 3.8e-15 56.6 0.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EER29028.1 - 5.3e-09 36.3 2.3 0.00011 22.1 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EER29028.1 - 0.00021 21.0 0.2 0.00054 19.6 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EER29028.1 - 0.0014 18.1 0.1 1.5 8.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EER29028.1 - 0.0066 16.2 0.2 0.0096 15.7 0.2 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EER29028.1 - 0.011 16.2 0.2 0.017 15.6 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EER29028.1 - 0.02 14.5 0.1 0.036 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EER29028.1 - 0.026 14.4 0.1 0.041 13.8 0.1 1.2 1 0 0 1 1 1 0 RsgA GTPase DUF3584 PF12128.8 EER29028.1 - 0.034 11.7 0.2 0.046 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MMR_HSR1 PF01926.23 EER29028.1 - 0.043 13.9 0.3 0.083 13.0 0.3 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EER29028.1 - 0.054 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EER29028.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EER29028.1 - 0.12 12.8 0.5 0.19 12.1 0.5 1.6 1 1 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EER29028.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EER29028.1 - 0.19 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EER29028.1 - 0.2 11.9 0.4 0.42 10.9 0.4 1.8 1 1 0 1 1 1 0 AAA domain AAA_13 PF13166.6 EER29028.1 - 0.3 9.7 0.2 0.41 9.2 0.2 1.1 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 EER29029.1 - 7.1e-35 118.5 22.1 2.5e-05 24.9 0.0 12.1 12 0 0 12 12 12 8 WD domain, G-beta repeat Glyco_hydro_49N PF17433.2 EER29029.1 - 0.041 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 N-terminal Ig-like domain IGF2_C PF08365.11 EER29029.1 - 0.092 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Insulin-like growth factor II E-peptide Urm1 PF09138.11 EER29030.1 - 4.7e-37 126.2 0.0 5.4e-37 126.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EER29030.1 - 0.013 16.1 0.0 0.016 15.8 0.0 1.2 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.18 EER29031.1 - 9.3e-54 182.1 0.0 1.4e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EER29031.1 - 1.1e-20 74.1 1.1 6.6e-20 71.6 1.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EER29031.1 - 0.017 15.2 0.1 0.095 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 EER29031.1 - 0.043 13.3 0.0 0.07 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ComC PF03047.14 EER29031.1 - 0.17 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 COMC family Porin_3 PF01459.22 EER29032.1 - 3.3e-84 282.5 0.0 3.8e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 EER29032.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.25 EER29033.1 - 6.1e-67 225.8 0.0 8.8e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29033.1 - 1.8e-25 89.7 0.0 3.3e-25 88.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EER29033.1 - 1.6e-06 27.7 0.0 4.2e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EER29033.1 - 0.00076 19.5 0.0 0.0073 16.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EER29033.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EER29033.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase MIF4G_like PF09088.11 EER29034.1 - 1.5e-88 295.6 0.2 2.3e-88 295.0 0.2 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EER29034.1 - 5.5e-73 245.7 0.1 1.5e-72 244.3 0.0 1.7 2 0 0 2 2 2 1 MIF4G like FA_hydroxylase PF04116.13 EER29035.1 - 3.9e-23 82.2 19.0 4.2e-23 82.1 15.9 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily WD40 PF00400.32 EER29036.1 - 3.7e-64 211.1 14.4 3.2e-10 40.4 1.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER29036.1 - 5.2e-21 74.7 0.0 3.2e-05 24.1 0.0 6.4 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EER29036.1 - 1.5e-16 60.4 7.5 2.6e-16 59.7 7.5 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 EER29036.1 - 2.8e-08 33.4 0.0 0.019 14.3 0.1 4.7 3 1 2 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 EER29036.1 - 3.8e-07 29.4 0.2 1.1 8.1 0.0 5.4 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EER29036.1 - 2.4e-06 26.4 1.2 0.0003 19.4 0.8 3.1 2 1 1 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.11 EER29036.1 - 9.6e-06 25.6 0.0 0.027 14.3 0.0 3.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EER29036.1 - 0.0002 20.2 0.0 0.25 9.9 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.12 EER29036.1 - 0.034 14.1 0.1 44 4.2 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EER29036.1 - 0.065 12.6 0.0 14 4.9 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal GAS PF13851.6 EER29036.1 - 0.1 12.0 3.0 0.15 11.4 3.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HPS3_N PF14761.6 EER29036.1 - 0.16 11.5 0.0 1.3 8.5 0.0 2.2 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Nucleoporin_N PF08801.11 EER29036.1 - 0.19 10.4 0.0 28 3.3 0.1 3.6 2 1 1 3 3 3 0 Nup133 N terminal like zf-C2H2 PF00096.26 EER29039.1 - 2.2e-14 53.0 22.7 0.00024 21.4 0.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER29039.1 - 1e-10 41.5 22.9 6.2e-08 32.7 1.1 4.8 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER29039.1 - 1.5e-07 31.6 18.2 0.015 16.1 0.2 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 EER29039.1 - 3e-06 27.4 5.6 0.0089 16.4 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EER29039.1 - 0.033 14.3 2.0 0.058 13.5 0.2 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger zf-LYAR PF08790.11 EER29039.1 - 0.092 12.7 4.2 7.5 6.6 0.2 3.4 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Mito_carr PF00153.27 EER29041.1 - 2.2e-69 229.4 1.4 6.2e-22 77.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.22 EER29042.1 - 1.7e-35 120.7 0.0 2.1e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER29042.1 - 0.00055 19.5 0.0 0.1 12.2 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER29042.1 - 0.00064 19.8 0.0 0.007 16.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif Cas_Cas2CT1978 PF09707.10 EER29042.1 - 0.012 15.7 0.0 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.8 EER29042.1 - 0.03 14.4 0.1 3.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 OB_RNB PF08206.11 EER29042.1 - 0.15 11.7 0.3 18 5.1 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2015 PF09435.10 EER29043.1 - 2e-44 150.0 0.0 2.3e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EER29044.1 - 5.4e-34 117.4 0.1 7e-34 117.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.23 EER29045.1 - 7.7e-45 152.5 0.3 1.6e-44 151.5 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EER29045.1 - 4.6e-42 143.8 0.0 6.1e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EER29045.1 - 0.00017 20.7 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EER29045.1 - 0.051 13.1 0.1 0.19 11.2 0.0 1.9 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.16 EER29046.1 - 1.8e-47 160.8 0.0 2.1e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.6 EER29047.1 - 1.9e-31 109.4 0.2 3.7e-31 108.5 0.2 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EER29047.1 - 1.8e-22 78.8 6.6 3.1e-22 78.0 6.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EER29047.1 - 3.9e-06 26.6 3.0 8.9e-06 25.4 3.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 EER29047.1 - 1.9e-05 24.3 1.2 0.0001 22.0 0.1 2.3 2 0 0 2 2 2 1 SAP domain zf-Sec23_Sec24 PF04810.15 EER29047.1 - 0.0097 15.9 1.4 0.024 14.7 1.4 1.7 1 1 0 1 1 1 1 Sec23/Sec24 zinc finger Prok-RING_4 PF14447.6 EER29047.1 - 0.089 12.7 3.2 0.18 11.7 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EER29047.1 - 1.2 9.4 4.6 2.2 8.5 4.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2423 PF10338.9 EER29048.1 - 5.6e-20 71.3 4.4 5.6e-20 71.3 4.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.22 EER29049.1 - 9.5e-14 51.7 1.8 1.2e-08 34.9 0.2 2.3 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EER29049.1 - 0.0026 17.2 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.18 EER29049.1 - 0.0054 16.1 0.0 0.0093 15.3 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily NAD_binding_10 PF13460.6 EER29051.1 - 8.8e-16 58.3 0.2 7.3e-15 55.3 0.2 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EER29051.1 - 2.2e-09 37.2 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EER29051.1 - 3.8e-08 33.2 0.3 5.8e-08 32.6 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EER29051.1 - 1.4e-05 24.4 0.1 3.4e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.18 EER29051.1 - 1.6e-05 25.1 1.0 2.4e-05 24.6 0.1 1.7 3 0 0 3 3 1 1 TrkA-N domain GDP_Man_Dehyd PF16363.5 EER29051.1 - 4.1e-05 23.2 0.0 7.7e-05 22.2 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EER29051.1 - 5.8e-05 22.6 0.1 9.3e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EER29051.1 - 6.5e-05 23.2 0.1 0.00013 22.2 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EER29051.1 - 0.0017 17.6 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_2 PF03446.15 EER29051.1 - 0.0022 18.2 0.0 0.0047 17.1 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 EER29051.1 - 0.0024 17.8 0.1 0.0039 17.1 0.1 1.3 1 0 0 1 1 1 1 KR domain CbiJ PF02571.14 EER29051.1 - 0.0037 16.8 0.1 0.005 16.4 0.1 1.2 1 0 0 1 1 1 1 Precorrin-6x reductase CbiJ/CobK 3Beta_HSD PF01073.19 EER29051.1 - 0.0097 14.9 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EER29051.1 - 0.014 15.8 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.15 EER29051.1 - 0.017 15.0 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_4 PF07993.12 EER29051.1 - 0.05 12.8 0.1 0.088 12.0 0.1 1.5 1 1 0 1 1 1 0 Male sterility protein DapB_N PF01113.20 EER29051.1 - 0.064 13.4 0.1 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_transf_4 PF13439.6 EER29051.1 - 0.09 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ApbA PF02558.16 EER29051.1 - 0.11 12.1 0.1 0.23 11.1 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RRM_2 PF04059.12 EER29052.1 - 1.4e-09 38.0 0.3 3.6e-09 36.7 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 EER29052.1 - 0.00084 19.1 0.5 0.42 10.5 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.23 EER29053.1 - 5.1e-07 29.9 0.0 1.1e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sec15 PF04091.12 EER29054.1 - 1.1e-110 370.0 0.3 1.1e-110 370.0 0.3 2.1 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 EER29054.1 - 0.0044 17.2 8.0 0.01 16.0 5.0 2.8 1 1 1 2 2 2 1 Golgi transport complex subunit 5 Sec8_exocyst PF04048.14 EER29054.1 - 0.011 15.7 2.8 0.04 13.8 2.8 2.0 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EER29054.1 - 0.13 11.6 6.4 0.3 10.3 6.4 1.6 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EER29054.1 - 0.19 11.8 7.0 0.15 12.2 4.4 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec5 PF15469.6 EER29054.1 - 0.76 9.6 6.6 1.1 9.1 2.9 2.9 3 1 0 3 3 3 0 Exocyst complex component Sec5 ApoLp-III PF07464.11 EER29054.1 - 1.1 9.3 6.4 0.28 11.3 1.5 2.4 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) CBFD_NFYB_HMF PF00808.23 EER29055.1 - 2.6e-19 69.3 0.1 1.4e-18 66.9 0.6 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EER29055.1 - 1.6e-15 57.6 0.1 1.6e-15 57.6 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EER29055.1 - 0.056 13.8 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pex14_N PF04695.13 EER29055.1 - 0.3 11.7 9.1 1.1 9.9 2.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fcf2 PF08698.11 EER29056.1 - 3.4e-38 129.9 0.2 3.4e-38 129.9 0.2 1.8 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.20 EER29057.1 - 2.9e-39 134.7 0.9 3.8e-31 108.2 0.1 2.3 2 1 0 2 2 2 2 Phosphorylase superfamily Ribosomal_S10 PF00338.22 EER29058.1 - 5.1e-26 90.8 0.0 8.4e-26 90.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.25 EER29059.1 - 1.6e-71 241.0 0.0 2.2e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Oxygenase-NA PF09859.9 EER29061.1 - 0.044 13.3 0.5 0.078 12.5 0.1 1.6 2 0 0 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA SWIRM PF04433.17 EER29062.1 - 4e-13 49.5 0.1 1.7e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain DUF4360 PF14273.6 EER29063.1 - 9.1e-67 224.4 0.1 1.1e-66 224.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CDC50 PF03381.15 EER29064.1 - 1.2e-97 326.8 0.0 1.5e-97 326.5 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Chorismate_synt PF01264.21 EER29064.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Chorismate synthase SPT16 PF08644.11 EER29065.1 - 1.1e-56 191.2 0.0 3.6e-56 189.5 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EER29065.1 - 4.2e-53 179.5 0.0 1.3e-52 177.9 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EER29065.1 - 2.5e-25 89.4 0.0 3.9e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EER29065.1 - 1.3e-14 54.4 0.0 3.1e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Mito_carr PF00153.27 EER29066.1 - 1.1e-19 70.1 0.1 4.2e-12 45.8 0.0 3.0 3 0 0 3 3 3 2 Mitochondrial carrier protein Sugar_tr PF00083.24 EER29067.1 - 7.4e-102 341.5 15.0 8.8e-102 341.3 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER29067.1 - 3.8e-31 108.3 44.6 2.1e-29 102.6 20.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EER29067.1 - 1e-08 34.2 15.5 4.6e-05 22.2 5.1 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EER29067.1 - 0.00014 20.8 5.4 0.11 11.3 0.1 2.3 1 1 1 2 2 2 2 MFS_1 like family INSIG PF07281.12 EER29067.1 - 0.24 11.0 4.4 0.23 11.1 1.7 2.1 2 0 0 2 2 2 0 Insulin-induced protein (INSIG) PMT PF02366.18 EER29068.1 - 3e-91 305.4 18.3 3e-91 305.4 18.3 2.3 2 0 0 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EER29068.1 - 6.1e-65 218.6 19.0 6.1e-65 218.6 19.0 2.6 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EER29068.1 - 1.1e-35 123.1 0.2 1.8e-35 122.5 0.2 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.22 EER29069.1 - 6.4e-46 155.9 0.0 5.5e-35 120.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EER29069.1 - 2e-27 95.8 0.0 3.5e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER29069.1 - 2e-08 33.9 0.0 1.8e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EER29069.1 - 4.1e-06 26.5 0.0 2.6e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EER29069.1 - 9.7e-05 21.8 0.0 0.0005 19.5 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EER29069.1 - 0.00048 20.1 0.0 0.35 10.7 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EER29069.1 - 0.0011 19.0 0.0 0.011 15.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Peroxin-3 PF04882.12 EER29069.1 - 0.0071 15.4 0.8 0.01 14.9 0.8 1.1 1 0 0 1 1 1 1 Peroxin-3 AAA_22 PF13401.6 EER29069.1 - 0.18 12.1 0.1 1 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Choline_transpo PF04515.12 EER29070.1 - 8.2e-22 77.8 21.6 8.2e-22 77.8 21.6 2.3 2 0 0 2 2 2 2 Plasma-membrane choline transporter MFS_1 PF07690.16 EER29072.1 - 5.4e-14 51.9 0.9 6.4e-13 48.3 1.5 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 EER29073.1 - 2.6e-06 27.5 7.8 4.4e-06 26.7 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 EER29074.1 - 4.2e-45 154.2 0.2 1e-43 149.7 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.14 EER29075.1 - 1.6e-128 429.4 0.0 2.1e-128 429.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-CCHC PF00098.23 EER29077.1 - 9.1e-45 148.8 56.8 4.7e-09 35.9 2.3 6.9 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.6 EER29077.1 - 1.7e-10 40.5 34.3 0.095 12.4 1.3 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.6 EER29077.1 - 7.7e-05 22.6 45.4 0.02 14.8 1.1 6.2 1 1 5 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.6 EER29077.1 - 0.02 14.7 38.8 0.56 10.1 0.5 6.2 6 0 0 6 6 6 0 Zinc knuckle zf-CCHC_5 PF14787.6 EER29077.1 - 0.069 12.9 39.7 1.2 8.9 0.4 6.3 5 1 1 6 6 6 0 GAG-polyprotein viral zinc-finger F-box PF00646.33 EER29078.1 - 4.7e-09 35.9 1.1 8.5e-09 35.1 1.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EER29078.1 - 2.4e-08 33.7 1.0 4.7e-08 32.8 1.0 1.5 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 EER29078.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain CNH PF00780.22 EER29078.1 - 0.08 12.5 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 0 CNH domain SAE2 PF08573.10 EER29079.1 - 2.5e-30 105.9 4.1 3e-30 105.6 0.0 3.0 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus JIP_LZII PF16471.5 EER29079.1 - 0.0015 18.7 3.7 0.0047 17.1 3.7 1.8 1 0 0 1 1 1 1 JNK-interacting protein leucine zipper II TolA_bind_tri PF16331.5 EER29079.1 - 0.007 16.4 4.9 0.015 15.4 4.4 1.7 2 0 0 2 2 1 1 TolA binding protein trimerisation bZIP_1 PF00170.21 EER29079.1 - 0.021 14.9 1.2 0.068 13.3 1.2 1.8 1 0 0 1 1 1 0 bZIP transcription factor KASH_CCD PF14662.6 EER29079.1 - 0.027 14.3 6.7 0.05 13.4 6.7 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH CASP_C PF08172.12 EER29079.1 - 0.036 13.4 2.8 0.076 12.4 2.8 1.5 1 0 0 1 1 1 0 CASP C terminal Sipho_Gp157 PF05565.11 EER29079.1 - 0.047 13.7 4.2 0.041 13.9 1.6 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 Ax_dynein_light PF10211.9 EER29079.1 - 0.086 12.8 2.4 0.22 11.5 2.4 1.7 1 0 0 1 1 1 0 Axonemal dynein light chain APG6_N PF17675.1 EER29079.1 - 0.09 13.3 5.0 0.23 12.0 5.0 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 EER29079.1 - 0.14 12.8 0.5 0.35 11.5 0.5 1.7 1 0 0 1 1 1 0 Initiation control protein YabA Cnn_1N PF07989.11 EER29079.1 - 0.31 11.2 6.0 0.76 10.0 6.0 1.7 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 EER29079.1 - 0.72 10.3 7.5 1.8 9.0 7.5 1.6 1 0 0 1 1 1 0 Cell division protein ZapB bZIP_2 PF07716.15 EER29079.1 - 0.75 9.9 9.2 0.078 13.1 2.6 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Pex16 PF08610.10 EER29080.1 - 2.9e-141 470.3 0.0 3.3e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) FAS_N PF17828.1 EER29080.1 - 0.021 14.8 0.1 0.034 14.1 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta RNase_HII PF01351.18 EER29081.1 - 1.9e-46 158.4 0.0 5.3e-46 157.0 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.8 EER29082.1 - 2.1e-34 117.6 1.0 4.2e-34 116.6 1.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 EER29082.1 - 1.5e-33 116.4 5.4 1.5e-33 116.4 5.4 4.0 4 2 0 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 EER29082.1 - 2e-07 30.6 0.0 4.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CAP_GLY PF01302.25 EER29083.1 - 1.3e-25 89.2 0.0 2.3e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EER29083.1 - 1.8e-15 57.1 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EER29083.1 - 0.005 16.6 0.0 0.012 15.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.12 EER29084.1 - 2e-10 41.2 0.0 4.1e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER29084.1 - 2e-09 38.0 0.0 5.2e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER29084.1 - 6.9e-06 26.0 0.0 9.3e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER29084.1 - 1e-05 26.2 0.0 1.9e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER29084.1 - 0.00063 19.6 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Myb_DNA-binding PF00249.31 EER29085.1 - 6.4e-13 48.7 1.1 9.7e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER29085.1 - 1.2e-06 28.7 2.0 0.0041 17.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 EER29085.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase UCH PF00443.29 EER29086.1 - 2.9e-16 59.7 0.0 4.8e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EER29086.1 - 6.3e-13 49.0 0.0 1.1e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SWIM PF04434.17 EER29086.1 - 2.9 7.6 5.4 11 5.8 0.1 2.7 2 0 0 2 2 2 0 SWIM zinc finger MitMem_reg PF13012.6 EER29087.1 - 7.5e-37 126.2 0.8 1.7e-36 125.1 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EER29087.1 - 1.4e-30 105.7 0.1 3.8e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EER29087.1 - 0.11 12.2 8.8 0.16 11.6 8.8 1.3 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 EER29087.1 - 3.4 7.3 7.1 6 6.5 7.1 1.5 1 1 0 1 1 1 0 Connexin ADK PF00406.22 EER29088.1 - 4.9e-61 205.3 0.1 6.1e-61 204.9 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EER29088.1 - 5.7e-23 81.8 1.2 6.1e-23 81.8 0.2 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EER29088.1 - 3.4e-17 62.1 0.0 7e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EER29088.1 - 7.8e-05 22.9 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EER29088.1 - 0.00019 22.0 0.0 0.0003 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EER29088.1 - 0.0097 15.8 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase SRP54 PF00448.22 EER29088.1 - 0.033 13.8 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 EER29088.1 - 0.087 12.5 0.2 0.33 10.6 0.1 1.9 1 1 1 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 EER29088.1 - 0.1 12.3 0.0 0.2 11.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain HNH_2 PF13391.6 EER29090.1 - 2.1e-11 43.8 0.1 5.3e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease GFO_IDH_MocA PF01408.22 EER29091.1 - 7.7e-18 65.5 0.1 1.2e-17 64.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EER29091.1 - 0.019 15.6 0.0 0.034 14.8 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.17 EER29091.1 - 0.053 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CFIA_Pcf11 PF11526.8 EER29092.1 - 1.8e-09 37.9 0.5 1.8e-09 37.9 0.5 2.4 2 0 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 EER29092.1 - 2.4e-06 28.3 0.0 7.4e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 EER29092.1 - 0.0077 16.1 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 VHS domain zf-ISL3 PF14690.6 EER29092.1 - 0.046 14.4 0.2 0.12 13.1 0.2 1.7 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf_UBZ PF18439.1 EER29092.1 - 1.2 8.8 8.3 2 8.1 1.0 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 EER29092.1 - 1.6 8.7 5.1 18 5.4 1.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ERG4_ERG24 PF01222.17 EER29094.1 - 8.1e-159 529.0 8.3 9.6e-159 528.7 8.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EER29094.1 - 0.00067 19.2 0.2 0.00067 19.2 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Methyltransf_23 PF13489.6 EER29095.1 - 7.3e-19 68.2 0.0 1.3e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER29095.1 - 1.2e-09 38.8 0.0 2.7e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER29095.1 - 2.1e-08 34.7 0.0 4.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER29095.1 - 7.3e-06 26.6 0.0 5.2e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER29095.1 - 1e-05 25.4 0.0 9.6e-05 22.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EER29095.1 - 0.0015 17.8 0.0 0.0028 17.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 EER29095.1 - 0.0056 16.4 0.0 0.0087 15.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 EER29095.1 - 0.0081 16.3 0.0 0.025 14.7 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 EER29095.1 - 0.023 14.2 0.0 0.061 12.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EER29095.1 - 0.058 12.7 0.0 0.44 9.8 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EER29095.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HOOK PF05622.12 EER29096.1 - 9.9e-25 86.8 33.1 9.9e-25 86.8 33.1 3.2 1 1 1 3 3 3 2 HOOK protein Bacillus_HBL PF05791.11 EER29096.1 - 0.015 15.1 39.0 0.024 14.5 1.3 5.9 4 1 2 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) SlyX PF04102.12 EER29096.1 - 0.24 12.0 0.2 0.24 12.0 0.2 9.5 8 2 1 10 10 10 0 SlyX DUF3800 PF12686.7 EER29096.1 - 0.35 11.5 4.3 50 4.6 4.4 3.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) KASH_CCD PF14662.6 EER29096.1 - 0.65 9.8 88.6 0.043 13.6 17.5 5.8 3 2 2 5 5 5 0 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 EER29096.1 - 3 8.0 95.3 0.021 15.1 15.3 6.1 2 2 1 5 5 5 0 Autophagy protein 16 (ATG16) VASP_tetra PF08776.11 EER29096.1 - 4.9 6.8 10.6 3.4 7.3 0.2 4.5 4 0 0 4 4 4 0 VASP tetramerisation domain Coprogen_oxidas PF01218.18 EER29097.1 - 1.8e-136 453.7 0.0 3e-136 453.0 0.0 1.3 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.16 EER29098.1 - 6e-51 171.0 0.2 7e-51 170.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EER29098.1 - 1.4e-06 28.6 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pkinase PF00069.25 EER29099.1 - 0.048 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain PSD5 PF07637.11 EER29099.1 - 0.11 12.9 0.3 30 5.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1595) Mito_carr PF00153.27 EER29101.1 - 7.2e-29 99.6 1.8 4e-15 55.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Wzy_C_2 PF11846.8 EER29104.1 - 6.2 6.7 6.5 0.32 10.9 0.8 1.7 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal adh_short PF00106.25 EER29105.1 - 2.2e-23 82.7 0.0 2.2e-19 69.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EER29105.1 - 5.1e-15 55.7 0.1 1.7e-13 50.7 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER29105.1 - 8.2e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EER29105.1 - 0.00059 19.3 0.0 0.0026 17.2 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EER29105.1 - 0.00089 18.8 0.0 0.0036 16.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family APH PF01636.23 EER29107.1 - 5.9e-05 23.1 0.0 0.00025 21.0 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mus7 PF09462.10 EER29108.1 - 3.2e-184 614.3 0.0 4.4e-184 613.8 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.12 EER29109.1 - 1.4e-32 112.3 6.4 1.4e-32 112.3 6.4 3.9 3 1 0 3 3 3 1 PAPA-1-like conserved region Pex14_N PF04695.13 EER29110.1 - 6.5e-42 143.9 5.5 6.5e-42 143.9 5.5 2.5 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 EER29110.1 - 0.0097 16.0 1.0 0.075 13.1 0.3 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Rab5-bind PF09311.11 EER29110.1 - 0.022 14.2 0.1 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 Rabaptin-like protein PI3K_P85_iSH2 PF16454.5 EER29110.1 - 0.084 12.5 0.9 6 6.5 0.0 2.7 3 0 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Sec16_C PF12931.7 EER29111.1 - 1.3e-05 25.0 1.2 0.0002 21.1 1.2 2.2 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 EER29111.1 - 2.7e-05 24.8 3.2 0.2 12.6 0.1 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER29111.1 - 0.018 15.4 0.1 0.16 12.3 0.0 2.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 EER29112.1 - 6.2e-15 54.8 0.1 2.9e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER29112.1 - 0.029 14.5 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif COX6B PF02297.17 EER29114.1 - 6.8e-19 67.9 6.0 8.4e-19 67.6 6.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EER29114.1 - 0.0076 16.2 1.9 0.013 15.5 1.7 1.5 1 1 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 EER29114.1 - 0.026 14.4 1.4 0.034 14.1 1.0 1.5 1 1 0 1 1 1 0 APOBEC-like C-terminal domain Mito_carr PF00153.27 EER29115.1 - 1.4e-46 156.4 0.9 5.1e-18 64.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.20 EER29116.1 - 8.2e-45 153.2 0.2 1.5e-23 83.5 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EER29116.1 - 8.6e-29 99.8 0.0 2.8e-28 98.2 0.0 1.9 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 EER29116.1 - 0.056 12.5 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) GrpE PF01025.19 EER29117.1 - 2.2e-42 144.6 2.4 3e-42 144.1 2.4 1.3 1 0 0 1 1 1 1 GrpE Uds1 PF15456.6 EER29118.1 - 1.6e-30 105.9 7.7 1.6e-30 105.9 7.7 2.0 2 0 0 2 2 2 1 Up-regulated During Septation Stathmin PF00836.19 EER29118.1 - 0.0096 15.9 5.2 0.03 14.3 5.2 1.8 1 0 0 1 1 1 1 Stathmin family CENP-Q PF13094.6 EER29118.1 - 1.3 9.2 7.5 15 5.8 7.5 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Lactonase PF10282.9 EER29119.1 - 2e-90 303.5 0.0 2.3e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Calcipressin PF04847.12 EER29120.1 - 6.7e-32 110.7 0.4 9.5e-32 110.2 0.4 1.2 1 0 0 1 1 1 1 Calcipressin Phage_cap_P2 PF05125.12 EER29120.1 - 0.063 12.3 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Phage major capsid protein, P2 family Transp_cyt_pur PF02133.15 EER29121.1 - 9.6e-38 130.1 32.7 1.1e-35 123.3 32.7 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATE_C PF04377.15 EER29122.1 - 2.9e-26 92.7 8.2 2.2e-23 83.3 8.2 2.5 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EER29122.1 - 3.5e-23 81.8 5.3 5.3e-23 81.2 4.2 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus RNA_pol_A_bac PF01000.26 EER29123.1 - 1.1e-31 109.4 0.0 1.8e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EER29123.1 - 2.6e-17 62.0 0.0 3.7e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.16 EER29123.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF22 RVT_2 PF07727.14 EER29124.1 - 6.1e-51 173.4 0.0 9.3e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EER29124.1 - 1.7e-14 54.0 0.0 8.9e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EER29124.1 - 4.2e-06 26.5 0.1 1.1e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.23 EER29124.1 - 0.001 19.0 1.7 0.0022 18.0 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle Retrotran_gag_2 PF14223.6 EER29124.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type rve_3 PF13683.6 EER29124.1 - 0.082 12.7 0.1 2.8 7.8 0.0 3.0 2 0 0 2 2 2 0 Integrase core domain Neugrin PF06413.11 EER29124.1 - 0.22 11.5 7.2 0.49 10.4 5.9 2.3 2 0 0 2 2 2 0 Neugrin NUDIX PF00293.28 EER29125.1 - 1.1e-18 67.6 0.6 1.3e-18 67.3 0.6 1.0 1 0 0 1 1 1 1 NUDIX domain DUF2816 PF10992.8 EER29126.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2816) Lactonase PF10282.9 EER29126.1 - 0.048 12.9 0.1 4.8 6.3 0.0 2.4 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Baculo_PEP_C PF04513.12 EER29127.1 - 0.17 12.0 0.4 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3439 PF11921.8 EER29127.1 - 1.4 8.9 4.0 2.7 8.0 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cytochrom_C PF00034.21 EER29128.1 - 4.9e-13 50.0 0.2 7.1e-13 49.5 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EER29128.1 - 1.1e-08 35.3 3.6 8e-08 32.5 3.6 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III CCP_MauG PF03150.14 EER29128.1 - 0.017 15.8 0.0 0.019 15.6 0.0 1.1 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase Cytochrom_C550 PF14495.6 EER29128.1 - 0.024 14.3 1.1 0.039 13.6 1.1 1.7 1 1 0 1 1 1 0 Cytochrome c-550 domain RNase_PH PF01138.21 EER29130.1 - 1.3e-11 45.1 0.1 3.6e-10 40.5 0.1 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Pkinase PF00069.25 EER29131.1 - 1.5e-57 195.0 0.0 2.5e-57 194.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29131.1 - 1.5e-33 116.2 0.0 2.9e-31 108.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EER29131.1 - 0.0061 15.6 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EER29131.1 - 0.044 12.7 0.0 0.066 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stn1 PF10451.9 EER29134.1 - 5e-13 48.6 0.1 5.3e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EER29134.1 - 5.2e-05 23.1 0.0 0.52 10.3 0.0 2.6 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain CDC45 PF02724.14 EER29134.1 - 0.024 12.9 4.5 0.031 12.6 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 EER29134.1 - 0.14 10.6 3.9 0.22 9.9 3.9 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 EER29134.1 - 0.16 11.7 5.9 5.7 6.7 7.3 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 V_ATPase_I PF01496.19 EER29134.1 - 0.39 8.6 1.8 0.51 8.2 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1682 PF07946.14 EER29134.1 - 3 7.0 14.4 3.9 6.6 14.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_S49_N PF08496.10 EER29134.1 - 3.5 7.7 7.7 5.4 7.1 7.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4228 PF14009.6 EER29134.1 - 4 7.8 7.9 2.2 8.6 5.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Connexin PF00029.19 EER29134.1 - 4 7.1 5.0 5.7 6.6 5.0 1.2 1 0 0 1 1 1 0 Connexin tRNA-synt_1b PF00579.25 EER29135.1 - 8.9e-23 81.0 0.0 1.8e-22 80.0 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) MFS_1 PF07690.16 EER29136.1 - 3.3e-30 105.2 39.3 3.3e-30 105.2 39.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER29136.1 - 2.6e-06 26.2 16.3 8.3e-06 24.5 16.4 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EER29136.1 - 1.5e-05 24.1 10.1 1.5e-05 24.1 10.1 2.6 3 0 0 3 3 3 2 Sugar (and other) transporter SET PF00856.28 EER29137.1 - 3.7e-14 53.5 0.1 3.1e-13 50.4 0.1 2.3 1 1 0 1 1 1 1 SET domain Inv-AAD PF18785.1 EER29138.1 - 6e-42 142.6 0.0 9.5e-42 141.9 0.0 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EER29138.1 - 1.2e-09 38.0 0.0 6.2e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EER29138.1 - 0.00013 21.9 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 EER29138.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 DnaJ PF00226.31 EER29139.1 - 2.3e-23 82.1 2.4 2.3e-23 82.1 2.4 2.2 2 0 0 2 2 2 1 DnaJ domain RPT PF13446.6 EER29139.1 - 0.025 14.5 0.0 0.088 12.8 0.0 2.0 1 0 0 1 1 1 0 A repeated domain in UCH-protein Usp PF00582.26 EER29140.1 - 1.5e-18 67.7 1.1 3.2e-10 40.7 0.2 2.8 2 1 0 2 2 2 2 Universal stress protein family Peptidase_S10 PF00450.22 EER29141.1 - 7.7e-76 256.2 0.0 1.2e-75 255.6 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase DUF4690 PF15756.5 EER29142.1 - 0.01 16.4 5.4 0.019 15.6 0.1 2.7 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 EER29142.1 - 0.015 15.4 2.2 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Podoplanin Cu_bind_like PF02298.17 EER29142.1 - 0.073 13.1 0.2 0.34 10.9 0.2 2.2 1 1 0 1 1 1 0 Plastocyanin-like domain DUF1983 PF09327.11 EER29142.1 - 0.42 10.7 1.3 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1983) ATP-synt_ab PF00006.25 EER29143.1 - 4.5e-68 229.1 0.0 7.4e-68 228.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EER29143.1 - 5.3e-12 46.1 0.3 1e-11 45.1 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Trp_syntA PF00290.20 EER29144.1 - 6.5e-94 313.6 0.0 1.2e-93 312.7 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EER29144.1 - 2.5e-47 161.7 2.6 4e-47 161.0 2.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.6 EER29144.1 - 0.033 13.8 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 0 Periplasmic binding protein ADH_zinc_N PF00107.26 EER29146.1 - 1.6e-23 83.1 0.3 2.4e-23 82.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER29146.1 - 1.4e-07 32.6 0.0 2.8e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EER29146.1 - 0.0001 22.1 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EER29146.1 - 0.0027 17.0 0.3 0.0043 16.4 0.3 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.25 EER29146.1 - 0.047 13.2 0.8 0.079 12.4 0.2 1.8 2 0 0 2 2 2 0 short chain dehydrogenase GAD PF02938.14 EER29146.1 - 0.056 13.7 0.1 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 GAD domain GYF PF02213.16 EER29147.1 - 3.5e-15 55.4 0.4 8.6e-15 54.1 0.4 1.7 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EER29147.1 - 0.062 13.1 2.5 0.21 11.4 0.2 2.9 3 0 0 3 3 3 0 GYF domain 2 Aminotran_5 PF00266.19 EER29148.1 - 1.4e-17 63.8 0.0 2.1e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EER29148.1 - 0.0022 16.6 0.0 0.0032 16.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EER29148.1 - 0.22 10.8 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-RING_2 PF13639.6 EER29149.1 - 7e-13 48.7 8.9 1.1e-12 48.1 8.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EER29149.1 - 5.7e-11 42.0 4.3 9.6e-11 41.2 4.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EER29149.1 - 1.6e-08 34.2 7.8 2.5e-08 33.6 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER29149.1 - 3.5e-06 26.8 3.8 4.8e-06 26.3 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER29149.1 - 7.1e-06 25.8 7.8 1.1e-05 25.1 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER29149.1 - 1.8e-05 24.6 5.6 2.7e-05 24.0 5.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EER29149.1 - 5.9e-05 23.3 11.8 0.00017 21.8 11.8 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EER29149.1 - 0.00016 21.7 2.9 0.00032 20.7 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EER29149.1 - 0.0024 17.7 5.0 0.0041 16.9 5.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EER29149.1 - 0.013 15.5 2.4 0.027 14.5 2.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ashwin PF15323.6 EER29149.1 - 0.12 12.4 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Developmental protein Zn_ribbon_17 PF17120.5 EER29149.1 - 0.14 11.8 6.8 0.26 10.9 6.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 EER29149.1 - 0.21 11.5 1.8 0.41 10.5 1.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EER29149.1 - 0.33 11.1 3.9 0.8 9.9 3.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EER29149.1 - 1.5 9.0 7.4 5.9 7.1 7.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EER29149.1 - 1.9 8.4 6.8 3.6 7.6 6.8 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 EER29149.1 - 2.7 8.2 10.0 5 7.3 10.0 1.4 1 0 0 1 1 1 0 RING-variant domain Fis1_TPR_C PF14853.6 EER29150.1 - 7e-27 93.3 1.3 1.1e-26 92.6 1.3 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EER29150.1 - 9e-18 63.7 0.0 1.8e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EER29150.1 - 0.0028 17.6 1.6 0.0067 16.5 1.6 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2957 PF11170.8 EER29150.1 - 0.087 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2957) Spc24 PF08286.11 EER29151.1 - 4.4e-37 126.5 2.7 4.8e-36 123.2 0.3 2.2 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 AAA_13 PF13166.6 EER29151.1 - 0.01 14.5 2.0 0.012 14.3 2.0 1.1 1 0 0 1 1 1 0 AAA domain FPP PF05911.11 EER29151.1 - 0.017 13.3 3.9 0.021 13.0 3.9 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 EER29151.1 - 0.018 15.6 8.5 0.025 15.1 8.5 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region CLZ PF16526.5 EER29151.1 - 0.098 13.0 8.1 0.31 11.4 2.0 2.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 EER29151.1 - 0.13 11.6 5.7 0.18 11.2 5.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4472 PF14739.6 EER29151.1 - 0.15 12.8 5.1 0.093 13.5 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) WXG100 PF06013.12 EER29151.1 - 0.15 12.3 3.4 0.18 12.1 0.2 2.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Phage_GPO PF05929.11 EER29151.1 - 0.33 10.5 4.5 1.7 8.2 4.5 1.9 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase GAS PF13851.6 EER29151.1 - 0.39 10.0 6.3 0.73 9.1 2.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 EER29151.1 - 0.48 10.4 5.4 0.81 9.7 1.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Nup54 PF13874.6 EER29151.1 - 0.95 9.6 8.1 7.4 6.7 8.1 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 MobC PF05713.11 EER29151.1 - 1.1 9.8 3.4 65 4.1 0.0 3.2 3 0 0 3 3 3 0 Bacterial mobilisation protein (MobC) Spc7 PF08317.11 EER29151.1 - 2.7 6.8 9.0 5 5.9 9.0 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein SlyX PF04102.12 EER29151.1 - 5.2 7.8 7.3 2.6 8.7 1.2 2.5 2 1 0 2 2 2 0 SlyX RIBIOP_C PF04950.12 EER29152.1 - 1.3e-95 320.2 0.0 1.3e-95 320.2 0.0 1.6 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EER29152.1 - 2.1e-29 101.4 0.0 6.3e-29 99.9 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EER29152.1 - 4.4e-05 23.8 0.2 0.00016 22.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain GTP_EFTU PF00009.27 EER29152.1 - 0.00011 21.8 0.0 0.014 14.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EER29152.1 - 0.00018 21.9 0.0 0.00063 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EER29152.1 - 0.00047 20.6 0.0 0.0013 19.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EER29152.1 - 0.00061 20.3 0.4 0.029 14.9 0.1 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EER29152.1 - 0.0011 19.1 0.1 0.0034 17.4 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EER29152.1 - 0.0013 18.9 1.8 0.0016 18.6 0.0 2.1 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 EER29152.1 - 0.0031 18.0 0.7 0.0081 16.7 0.0 2.0 2 0 0 2 2 1 1 ABC transporter AAA_19 PF13245.6 EER29152.1 - 0.0031 17.9 0.0 0.0064 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EER29152.1 - 0.0036 16.5 0.0 0.0084 15.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.15 EER29152.1 - 0.0081 16.1 0.2 0.017 15.1 0.2 1.5 1 0 0 1 1 1 1 NTPase NACHT PF05729.12 EER29152.1 - 0.0084 16.0 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 EER29152.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EER29152.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EER29152.1 - 0.019 14.5 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region MobB PF03205.14 EER29152.1 - 0.02 14.8 0.0 0.061 13.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.14 EER29152.1 - 0.024 13.9 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain cobW PF02492.19 EER29152.1 - 0.025 14.2 0.1 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EER29152.1 - 0.033 14.6 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PduV-EutP PF10662.9 EER29152.1 - 0.047 13.4 0.0 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 EER29152.1 - 0.054 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EER29152.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EER29152.1 - 0.069 12.9 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EER29152.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ATPase_2 PF01637.18 EER29152.1 - 0.075 12.9 1.4 0.095 12.6 0.0 1.9 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EER29152.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EER29152.1 - 0.11 11.5 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EER29152.1 - 0.11 12.5 0.2 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Roc PF08477.13 EER29152.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EER29152.1 - 0.12 11.6 0.2 0.55 9.5 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_11 PF13086.6 EER29152.1 - 0.18 11.6 0.0 0.18 11.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain Pkinase_fungal PF17667.1 EER29153.1 - 1.6e-140 468.5 0.0 2e-140 468.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EER29153.1 - 3.4e-07 29.9 0.0 5.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29153.1 - 0.0052 16.1 0.0 0.0092 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER29153.1 - 0.05 13.5 0.1 0.35 10.8 0.1 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EER29153.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF1989 PF09347.10 EER29154.1 - 4.1e-64 215.2 0.0 5e-64 215.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) PBP_like_2 PF12849.7 EER29155.1 - 3e-12 46.8 0.1 3.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_8 PF13416.6 EER29155.1 - 0.00081 19.3 0.5 0.0039 17.1 0.3 1.9 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein YaeQ PF07152.12 EER29156.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 YaeQ protein Tom5 PF10642.9 EER29157.1 - 0.15 12.1 0.2 0.23 11.5 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF3425 PF11905.8 EER29159.1 - 1.6e-12 47.5 2.6 1.7e-11 44.1 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_2 PF07716.15 EER29159.1 - 0.78 9.9 10.1 1.6 8.9 10.1 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 EER29159.1 - 3.4 7.8 14.2 0.37 10.9 9.5 1.8 2 0 0 2 2 2 0 bZIP transcription factor Abhydrolase_1 PF00561.20 EER29160.1 - 3.4e-11 43.3 0.0 9.1e-09 35.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER29160.1 - 8.2e-07 29.8 0.0 1.3e-06 29.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EER29160.1 - 1.3e-05 24.6 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BCDHK_Adom3 PF10436.9 EER29161.1 - 1.6e-45 154.9 0.0 2.2e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EER29161.1 - 6.9e-10 39.4 0.0 2.2e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carboxyl_trans PF01039.22 EER29162.1 - 1.6e-74 251.4 0.0 2.3e-74 250.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EER29163.1 - 6.4e-56 189.2 0.1 1e-55 188.5 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EER29163.1 - 5.6e-31 106.8 0.0 1.2e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EER29163.1 - 4.4e-12 46.5 0.0 1.2e-11 45.1 0.0 1.8 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EER29163.1 - 1.6e-10 40.7 0.4 1.6e-10 40.7 0.4 2.6 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EER29163.1 - 2e-09 37.3 0.1 4.6e-09 36.1 0.1 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EER29163.1 - 1.6e-06 27.8 0.1 2.9e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EER29163.1 - 1.7e-06 28.1 0.0 3.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EER29163.1 - 0.00032 20.0 0.0 0.00058 19.2 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 EER29163.1 - 0.0015 18.4 0.2 0.074 13.0 0.0 3.2 2 1 1 3 3 3 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 EER29163.1 - 0.011 15.6 0.0 3.2 7.7 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like DUF2118 PF09891.9 EER29163.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) EF-hand_13 PF17958.1 EER29163.1 - 0.026 14.3 0.0 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain AIM24 PF01987.17 EER29163.1 - 0.069 12.9 0.0 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial biogenesis AIM24 GSH-S_ATP PF02955.16 EER29163.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Haspin_kinase PF12330.8 EER29164.1 - 0.0053 15.7 0.0 0.0079 15.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain GCN5L1 PF06320.13 EER29165.1 - 3.4e-19 69.1 0.1 3.9e-19 68.9 0.1 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF3552 PF12072.8 EER29165.1 - 0.012 15.0 4.3 0.014 14.8 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2884 PF11101.8 EER29165.1 - 0.015 14.8 0.4 0.021 14.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) BST2 PF16716.5 EER29165.1 - 0.05 14.2 5.5 0.42 11.2 1.4 2.1 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 EER29165.1 - 0.06 12.2 4.1 0.07 12.0 4.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DNA_mis_repair PF01119.19 EER29166.1 - 1.5e-20 73.0 0.0 3.2e-19 68.8 0.0 2.8 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 EER29166.1 - 1.5e-17 63.8 0.5 6.6e-16 58.4 0.5 2.7 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EER29166.1 - 1.2e-12 47.8 0.0 3.5e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EER29166.1 - 2.1e-07 31.5 0.0 2.8e-06 27.8 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serinc PF03348.15 EER29167.1 - 9.2e-164 545.4 7.5 1.1e-163 545.2 7.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.16 EER29168.1 - 1.1e-08 34.5 36.9 1.6e-05 24.0 16.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EER29168.1 - 2.3e-07 30.6 2.2 2.3e-07 30.6 2.2 2.2 2 0 0 2 2 2 1 Nodulin-like GATA PF00320.27 EER29169.1 - 2.3e-15 55.9 2.6 4.7e-15 54.9 2.6 1.6 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.12 EER29169.1 - 4.7e-05 23.0 3.9 0.0062 16.3 2.2 2.6 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat DUF745 PF05335.13 EER29169.1 - 0.0097 15.6 2.5 0.018 14.7 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF745) DivIVA PF05103.13 EER29169.1 - 0.025 14.6 7.2 1.2 9.2 7.2 2.3 1 1 0 1 1 1 0 DivIVA protein HR1 PF02185.16 EER29169.1 - 0.042 14.0 5.8 0.1 12.7 5.8 1.7 1 0 0 1 1 1 0 Hr1 repeat Spc7 PF08317.11 EER29169.1 - 0.13 11.1 7.7 0.19 10.6 7.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Zn-ribbon_8 PF09723.10 EER29169.1 - 0.15 12.2 0.2 0.87 9.8 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain UPF0242 PF06785.11 EER29169.1 - 0.35 11.0 5.1 0.55 10.3 5.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus TF_Zn_Ribbon PF08271.12 EER29169.1 - 0.41 10.2 1.8 0.66 9.5 0.3 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EER29169.1 - 0.97 8.9 6.1 39 3.8 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 EER29169.1 - 1.2 9.2 3.9 2.7 8.1 0.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon bZIP_2 PF07716.15 EER29169.1 - 1.3 9.2 11.2 3.1 7.9 0.1 2.6 2 0 0 2 2 2 0 Basic region leucine zipper WD40_alt PF14077.6 EER29169.1 - 1.7 8.6 3.9 17 5.4 1.5 2.6 2 0 0 2 2 2 0 Alternative WD40 repeat motif Atg14 PF10186.9 EER29169.1 - 1.9 7.5 9.5 3.3 6.7 9.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zinc_ribbon_2 PF13240.6 EER29169.1 - 3.4 7.5 7.7 27 4.6 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DivIC PF04977.15 EER29169.1 - 4.7 7.0 7.5 2.1 8.1 3.4 2.1 2 0 0 2 2 2 0 Septum formation initiator JIP_LZII PF16471.5 EER29169.1 - 4.9 7.4 11.1 5.9e+02 0.7 11.1 2.3 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II PI3_PI4_kinase PF00454.27 EER29170.1 - 3.3e-43 148.3 0.0 5.9e-43 147.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.23 EER29171.1 - 4.3e-61 206.6 0.0 8e-61 205.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER29171.1 - 3.2e-11 43.6 0.0 1.1e-10 41.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EER29171.1 - 1.7e-06 28.0 0.0 5.2e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EER29171.1 - 0.00024 21.2 0.0 0.0006 19.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3873 PF12989.7 EER29171.1 - 0.017 15.5 0.0 0.3 11.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) Sec5 PF15469.6 EER29171.1 - 0.042 13.7 0.9 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 HIRAN PF08797.11 EER29171.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 HIRAN domain Med21 PF11221.8 EER29172.1 - 6.7e-55 185.3 12.1 1e-53 181.5 12.1 2.1 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 EER29172.1 - 0.03 14.4 1.7 0.075 13.1 1.7 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Troponin PF00992.20 EER29172.1 - 0.06 13.7 1.8 0.099 12.9 1.8 1.4 1 0 0 1 1 1 0 Troponin DUF3431 PF11913.8 EER29173.1 - 3.7e-87 291.6 0.0 4.5e-87 291.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF2034 PF10356.9 EER29174.1 - 1.3e-35 122.5 0.0 3.7e-20 72.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EER29174.1 - 2.5e-06 27.5 0.0 6.4e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 Restriction endonuclease DUF5004 PF16395.5 EER29174.1 - 0.23 11.5 0.0 0.35 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5004) Nup35_RRM_2 PF14605.6 EER29175.1 - 1.2e-06 28.4 0.0 0.00021 21.2 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EER29175.1 - 2.7e-06 27.1 0.1 1.7e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 EER29175.1 - 5.8e-05 23.3 3.1 0.00014 22.1 1.4 2.5 2 1 0 2 2 2 1 PWI domain RRM_occluded PF16842.5 EER29175.1 - 0.011 15.6 0.0 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-CCCH PF00642.24 EER29175.1 - 0.016 15.1 1.6 0.03 14.2 1.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Antigen_Bd37 PF11641.8 EER29175.1 - 0.039 13.5 1.2 0.078 12.5 1.2 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein zf_CCCH_4 PF18345.1 EER29175.1 - 0.14 12.2 1.3 0.28 11.3 1.3 1.5 1 0 0 1 1 1 0 Zinc finger domain PHM7_cyt PF14703.6 EER29175.1 - 1.1 9.4 8.4 1.7 8.8 0.0 2.6 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF3584 PF12128.8 EER29175.1 - 3.7 4.9 16.9 5 4.5 16.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 EER29175.1 - 4.9 6.6 7.2 7.5 6.0 7.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit adh_short_C2 PF13561.6 EER29177.1 - 6.3e-59 199.4 0.0 9.3e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER29177.1 - 6.2e-50 169.4 0.0 1.1e-49 168.6 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER29177.1 - 8.7e-06 25.8 0.0 1.6e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EER29177.1 - 0.00031 20.3 0.0 0.024 14.1 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 EER29177.1 - 0.031 13.6 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 EER29177.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GTP_EFTU PF00009.27 EER29179.1 - 1.8e-66 223.4 0.1 2.4e-66 223.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EER29179.1 - 1.3e-33 115.3 0.0 5e-33 113.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EER29179.1 - 1.2e-22 79.7 0.0 4.1e-22 78.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EER29179.1 - 2.8e-12 46.9 0.0 7.8e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EER29179.1 - 5.8e-12 45.5 0.0 1.5e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EER29179.1 - 0.00026 21.0 0.1 0.00065 19.8 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.16 EER29181.1 - 1.6e-93 313.1 9.3 2e-93 312.7 9.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Pil1 PF13805.6 EER29182.1 - 0.2 11.2 0.1 0.31 10.5 0.1 1.2 1 0 0 1 1 1 0 Eisosome component PIL1 Dynactin PF12455.8 EER29183.1 - 6.9e-99 330.7 5.2 6.9e-99 330.7 5.2 4.0 3 2 2 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 EER29183.1 - 2.8e-24 84.9 0.0 5.2e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain HALZ PF02183.18 EER29183.1 - 0.0015 18.7 23.6 0.059 13.6 0.2 6.9 4 1 2 6 6 6 3 Homeobox associated leucine zipper WD40_alt PF14077.6 EER29183.1 - 0.17 11.8 6.1 0.89 9.5 1.2 3.9 3 0 0 3 3 3 0 Alternative WD40 repeat motif Filo_VP35 PF02097.15 EER29183.1 - 0.23 10.5 6.0 0.24 10.4 0.8 3.1 3 0 0 3 3 3 0 Filoviridae VP35 DUF2353 PF09789.9 EER29183.1 - 0.26 10.6 66.6 0.021 14.2 5.7 4.4 2 1 2 4 4 4 0 Uncharacterized coiled-coil protein (DUF2353) HCMV_UL139 PF12507.8 EER29183.1 - 0.89 9.9 15.0 0.41 11.0 2.4 4.0 2 2 1 3 3 3 0 Human Cytomegalovirus UL139 protein APG6_N PF17675.1 EER29183.1 - 8.6 6.9 0.0 8.6 6.9 0.0 8.3 4 2 5 9 9 9 0 Apg6 coiled-coil region Hemerythrin PF01814.23 EER29184.1 - 1.2e-08 35.6 0.2 1.6e-08 35.2 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAD_2 PF13419.6 EER29185.1 - 5.3e-06 26.6 0.0 7.6e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EER29185.1 - 0.002 18.5 0.0 0.0025 18.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EER29185.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like KH_1 PF00013.29 EER29187.1 - 2.1e-35 120.4 0.1 3.8e-07 29.8 0.2 7.7 8 0 0 8 8 8 6 KH domain Chitin_synth_2 PF03142.15 EER29188.1 - 5.9e-248 823.8 0.7 8e-248 823.3 0.7 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EER29188.1 - 4.9e-75 253.1 0.0 4.5e-74 249.9 0.0 2.1 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.28 EER29188.1 - 2.2e-19 69.4 0.1 1.9e-14 53.6 0.0 3.8 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EER29188.1 - 1.5e-16 60.1 0.2 6.8e-16 57.9 0.4 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EER29188.1 - 1.1e-12 48.3 4.6 2.9e-12 46.9 4.6 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EER29188.1 - 5.1e-10 39.6 0.2 3.6e-09 36.8 0.1 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EER29188.1 - 0.00016 21.5 0.0 0.1 12.4 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 AAA_16 PF13191.6 EER29188.1 - 0.039 14.3 0.6 0.14 12.5 0.1 2.2 3 0 0 3 3 3 0 AAA ATPase domain RsgA_GTPase PF03193.16 EER29188.1 - 0.048 13.6 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase Glyco_transf_21 PF13506.6 EER29188.1 - 0.08 12.4 0.1 0.48 9.9 0.2 2.3 2 1 0 2 2 2 0 Glycosyl transferase family 21 AAA_7 PF12775.7 EER29188.1 - 0.18 11.3 0.0 0.4 10.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Chitin_synth_2 PF03142.15 EER29189.1 - 1.4e-228 759.8 0.0 2e-228 759.3 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Cyt-b5 PF00173.28 EER29189.1 - 1.9e-17 63.1 0.3 1.7e-11 44.1 0.1 3.4 3 1 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.11 EER29189.1 - 6.6e-17 61.2 0.4 2.9e-16 59.1 0.6 1.9 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 EER29189.1 - 1.4e-13 51.3 2.6 3.1e-13 50.1 2.6 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EER29189.1 - 9.2e-12 45.3 0.0 9.8e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EER29189.1 - 1.7e-09 36.5 0.0 2e-08 32.9 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 EER29189.1 - 0.0019 17.7 0.0 0.0052 16.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EER29189.1 - 0.0022 17.8 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 PLDc_2 PF13091.6 EER29190.1 - 3.8e-21 75.4 0.0 1.4e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EER29190.1 - 1.3e-07 31.5 0.0 0.025 14.8 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EER29190.1 - 0.025 13.8 0.0 0.5 9.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB TPP_enzyme_N PF02776.18 EER29191.1 - 5.4e-42 143.3 0.0 3.5e-41 140.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EER29191.1 - 2.9e-20 72.6 0.4 7e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EER29191.1 - 1.1e-14 54.3 0.2 2e-13 50.2 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain NTP_transf_3 PF12804.7 EER29191.1 - 0.22 11.9 1.3 1.1 9.6 0.4 2.6 2 1 0 2 2 2 0 MobA-like NTP transferase domain TatD_DNase PF01026.21 EER29192.1 - 2.1e-37 128.9 0.0 2.8e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase Abhydrolase_1 PF00561.20 EER29194.1 - 2.9e-20 73.0 0.0 3.2e-19 69.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER29194.1 - 3.8e-16 59.1 0.0 2.8e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EER29194.1 - 1.1e-14 55.5 9.9 1.2e-14 55.5 4.8 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 EER29194.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 EER29194.1 - 0.0012 18.2 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 EER29194.1 - 0.011 15.6 0.0 0.099 12.5 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase2 PF12740.7 EER29194.1 - 0.015 14.2 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.20 EER29194.1 - 0.039 14.1 0.3 0.22 11.6 0.3 2.1 1 1 0 1 1 1 0 Thioesterase domain LIDHydrolase PF10230.9 EER29194.1 - 0.04 13.5 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 EER29194.1 - 0.05 13.5 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EER29194.1 - 0.096 12.5 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Chlorophyllase PF07224.11 EER29194.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.16 EER29194.1 - 0.15 11.8 0.0 9.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Spo7 PF03907.13 EER29195.1 - 3.7e-92 307.8 0.0 5.5e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein U1snRNP70_N PF12220.8 EER29195.1 - 0.2 12.3 2.8 0.24 12.1 0.1 2.2 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal MCM PF00493.23 EER29196.1 - 3.7e-97 323.8 0.2 7.1e-97 322.9 0.2 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EER29196.1 - 3.4e-31 107.7 0.0 6.4e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EER29196.1 - 2.7e-24 85.4 0.8 6.9e-24 84.1 0.8 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EER29196.1 - 1.7e-12 47.8 0.0 6.6e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EER29196.1 - 6e-07 29.0 0.0 6.9e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EER29196.1 - 0.0024 17.8 0.0 0.0057 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EER29196.1 - 0.082 12.6 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 EER29196.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPR_2 PF13041.6 EER29197.1 - 5.4e-20 71.3 1.3 4.6e-12 45.9 0.0 6.3 5 1 2 7 7 7 3 PPR repeat family PPR PF01535.20 EER29197.1 - 7.1e-16 57.3 7.8 0.00024 21.2 0.0 9.0 8 0 0 8 8 8 3 PPR repeat PPR_3 PF13812.6 EER29197.1 - 2.8e-14 52.9 0.0 1.7e-05 24.8 0.0 5.0 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 EER29197.1 - 4.5e-09 35.9 1.8 0.023 14.4 0.0 5.3 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 EER29197.1 - 2e-06 27.3 0.0 7.2e-06 25.5 0.0 2.0 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP SRP68 PF16969.5 EER29198.1 - 1.1e-193 645.3 0.2 1.2e-193 645.1 0.2 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 p450 PF00067.22 EER29199.1 - 5.7e-56 190.2 0.0 8.4e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FSA_C PF10479.9 EER29200.1 - 0.99 7.5 4.8 1.2 7.2 4.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 EER29200.1 - 5.3 7.0 11.7 7.4 6.6 11.7 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Rhodanese PF00581.20 EER29201.1 - 2.4e-10 40.9 0.0 4e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain RlmM_FDX PF18125.1 EER29201.1 - 0.14 12.6 0.2 0.26 11.8 0.2 1.3 1 0 0 1 1 1 0 RlmM ferredoxin-like domain GTP_EFTU PF00009.27 EER29202.1 - 1.6e-34 119.2 1.6 2.3e-34 118.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EER29202.1 - 1.7e-19 69.9 0.1 4.9e-19 68.4 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 EER29202.1 - 3.5e-10 39.7 0.0 1.3e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EER29202.1 - 1.9e-09 37.8 0.0 1.9e-09 37.8 0.0 3.8 4 1 0 4 4 4 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EER29202.1 - 1.7e-06 28.1 0.2 1.3e-05 25.2 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EER29202.1 - 0.00017 21.8 0.0 0.00048 20.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EER29202.1 - 0.0093 15.8 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Ras PF00071.22 EER29202.1 - 0.064 12.9 0.0 0.47 10.0 0.0 2.5 2 1 0 2 2 2 0 Ras family MMS1_N PF10433.9 EER29203.1 - 3.2e-101 339.4 0.0 1.4e-99 334.0 0.0 2.6 2 1 1 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.6 EER29203.1 - 0.042 14.3 0.2 49 4.6 0.1 4.4 3 0 0 3 3 3 0 PQQ-like domain RabGAP-TBC PF00566.18 EER29204.1 - 6.5e-23 81.5 0.0 1.1e-22 80.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain US30 PF17624.2 EER29204.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function DAO PF01266.24 EER29205.1 - 1.1e-63 215.9 0.2 1.3e-63 215.8 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER29205.1 - 9.1e-06 25.8 0.6 2.2e-05 24.6 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EER29205.1 - 0.0007 18.9 0.1 0.079 12.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER29205.1 - 0.014 14.6 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EER29205.1 - 0.044 13.1 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EER29205.1 - 0.058 12.7 0.8 0.11 11.8 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EER29205.1 - 0.086 12.1 0.2 0.16 11.1 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EER29205.1 - 0.12 11.5 3.8 0.74 8.8 1.8 2.0 2 0 0 2 2 2 0 FAD binding domain APH PF01636.23 EER29206.1 - 3.5e-05 23.8 0.0 0.00015 21.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Vps52 PF04129.12 EER29207.1 - 1.4e-121 406.8 0.2 1.8e-121 406.4 0.2 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EER29207.1 - 0.0001 20.9 0.5 0.00035 19.1 0.6 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF812 PF05667.11 EER29207.1 - 0.00019 20.5 0.6 0.0018 17.2 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF812) MitMem_reg PF13012.6 EER29207.1 - 0.0025 18.2 2.2 0.2 12.1 0.8 3.6 2 1 0 2 2 2 1 Maintenance of mitochondrial structure and function COG6 PF06419.11 EER29207.1 - 0.0079 14.5 0.3 0.41 8.8 0.0 2.6 2 1 1 3 3 3 1 Conserved oligomeric complex COG6 Phage_GPO PF05929.11 EER29207.1 - 0.053 13.1 1.5 0.24 11.0 0.2 2.1 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase COG2 PF06148.11 EER29207.1 - 0.083 13.0 0.3 0.35 11.0 0.3 2.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 EER29207.1 - 0.14 12.6 0.5 1.3 9.5 0.3 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 EER29207.1 - 0.67 10.7 4.9 2.2 9.1 0.4 3.1 2 1 1 3 3 3 0 Occludin homology domain THOC7 PF05615.13 EER29207.1 - 1.9 8.8 4.7 3.2 8.0 1.5 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 APG6_N PF17675.1 EER29207.1 - 7.9 7.0 10.1 25 5.4 6.7 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region eIF-5a PF01287.20 EER29208.1 - 8.7e-29 99.4 1.7 1.2e-28 99.0 1.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EER29208.1 - 0.0029 17.6 0.5 0.0086 16.1 0.0 2.0 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain ubiquitin PF00240.23 EER29209.1 - 1.3e-33 114.6 1.6 1.2e-32 111.5 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.17 EER29209.1 - 1.9e-31 107.7 12.1 3.1e-31 107.0 12.1 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EER29209.1 - 2.3e-14 53.0 0.3 4.2e-14 52.1 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EER29209.1 - 9e-05 22.9 0.1 0.00031 21.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EER29209.1 - 0.0081 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EER29209.1 - 0.0099 15.8 0.6 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EER29209.1 - 0.025 14.7 0.0 0.057 13.5 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EER29209.1 - 0.056 14.0 0.1 0.1 13.2 0.1 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Glyco_hydro_81 PF03639.13 EER29209.1 - 0.063 12.4 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 N-terminal domain Yip1 PF04893.17 EER29210.1 - 1.1e-14 54.5 13.7 1.1e-14 54.5 13.7 1.3 1 1 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 EER29210.1 - 0.036 13.6 2.8 0.18 11.3 0.8 2.3 2 1 0 2 2 2 0 YIF1 RRM_1 PF00076.22 EER29211.1 - 1.3e-81 268.3 7.1 4.2e-23 80.9 0.5 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EER29211.1 - 5.6e-29 100.1 0.7 3.8e-28 97.5 0.8 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EER29211.1 - 1.3e-12 47.4 0.1 0.0036 16.9 0.0 5.0 2 1 3 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EER29211.1 - 3e-06 27.3 0.4 4.2 7.5 0.0 5.5 5 1 0 5 5 5 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EER29211.1 - 9.1e-05 22.4 0.6 4.3 7.4 0.0 4.5 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EER29211.1 - 0.00019 21.2 0.0 0.34 10.8 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EER29211.1 - 0.00021 21.3 9.8 0.22 11.6 2.1 4.8 5 1 0 5 5 5 2 RNA binding motif DUF2800 PF10926.8 EER29211.1 - 0.0017 17.7 0.3 0.0027 17.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2800) CbiG_mid PF11761.8 EER29211.1 - 0.0044 17.1 0.0 34 4.7 0.0 3.6 3 0 0 3 3 3 0 Cobalamin biosynthesis central region YflT PF11181.8 EER29211.1 - 0.0047 17.4 6.6 0.062 13.8 0.9 3.3 3 0 0 3 3 3 1 Heat induced stress protein YflT Limkain-b1 PF11608.8 EER29211.1 - 0.0096 16.0 1.4 12 6.1 0.0 3.6 3 0 0 3 3 3 0 Limkain b1 PhetRS_B1 PF18262.1 EER29211.1 - 0.067 13.4 0.4 14 6.0 0.1 3.3 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain OB_RNB PF08206.11 EER29211.1 - 0.18 11.5 2.1 18 5.1 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain SAPS PF04499.15 EER29211.1 - 0.24 10.2 5.8 0.46 9.2 5.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3887 PF13026.6 EER29211.1 - 2.2 9.1 6.0 1.7 9.5 2.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) Presenilin PF01080.17 EER29211.1 - 7.8 5.1 7.6 14 4.3 7.6 1.4 1 0 0 1 1 1 0 Presenilin HECT PF00632.25 EER29212.1 - 1.3e-80 271.2 0.0 1.4e-79 267.8 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EER29212.1 - 0.0024 17.5 0.4 0.0084 15.8 0.4 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif CSRNP_N PF16019.5 EER29212.1 - 0.29 11.0 0.2 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus MRP-L27 PF09809.9 EER29213.1 - 6.4e-13 48.5 0.1 7.6e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.13 EER29214.1 - 2.2e-208 694.5 68.8 2.2e-208 694.5 68.8 2.1 1 1 1 2 2 2 1 Utp14 protein Glyco_hydro81C PF17652.1 EER29215.1 - 4.3e-162 539.2 3.9 5.4e-162 538.9 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EER29215.1 - 5.5e-122 407.0 0.2 2.6e-121 404.8 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 81 N-terminal domain Na_Ca_ex PF01699.24 EER29216.1 - 1.5e-43 148.4 39.5 3.9e-22 78.8 16.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PAGK PF15284.6 EER29216.1 - 0.098 12.6 0.4 9.4 6.2 0.0 2.8 2 0 0 2 2 2 0 Phage-encoded virulence factor Ribosomal_S7 PF00177.21 EER29217.1 - 1.2e-30 106.1 0.0 3.2e-30 104.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e bZIP_2 PF07716.15 EER29218.1 - 2.2e-07 30.8 7.9 3.8e-07 30.1 7.9 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EER29218.1 - 1.3e-05 25.2 3.9 2.6e-05 24.2 3.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor DivIC PF04977.15 EER29218.1 - 0.019 14.7 2.1 0.032 14.0 2.1 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.17 EER29218.1 - 0.025 15.1 5.5 0.048 14.2 5.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor NAM-associated PF14303.6 EER29218.1 - 0.065 14.0 4.4 0.095 13.4 4.4 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain GvpL_GvpF PF06386.11 EER29218.1 - 0.15 12.0 3.5 0.24 11.3 3.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Peptidase_S28 PF05577.12 EER29219.1 - 4e-46 157.7 0.0 7.1e-45 153.6 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EER29219.1 - 0.057 12.9 0.0 0.88 9.0 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EER29219.1 - 0.084 12.1 0.0 9.3 5.4 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Methyltransf_2 PF00891.18 EER29220.1 - 1.5e-23 83.3 0.0 2.3e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Vac_Fusion PF02346.16 EER29220.1 - 0.1 12.3 0.0 3.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Methyltransf_16 PF10294.9 EER29220.1 - 0.2 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase SPX PF03105.19 EER29221.1 - 1.9e-39 136.7 0.0 3.1e-24 86.6 0.0 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EER29221.1 - 1.1e-32 113.7 38.0 1.6e-32 113.2 38.0 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EER29221.1 - 2.2e-29 102.6 52.5 1.5e-26 93.4 30.0 2.3 2 1 1 3 3 3 2 Citrate transporter DUF357 PF04010.13 EER29221.1 - 0.084 13.0 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Ribonuclease_T2 PF00445.18 EER29222.1 - 1.3e-42 146.1 2.8 2.3e-42 145.3 2.8 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family GT-D PF08759.11 EER29222.1 - 0.0077 15.9 0.5 0.011 15.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase GT-D fold Ribosomal_S8e PF01201.22 EER29223.1 - 1e-54 184.4 0.8 1.2e-54 184.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Metallophos PF00149.28 EER29224.1 - 6.7e-09 36.5 0.5 9.2e-09 36.1 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EER29224.1 - 1.4e-05 25.4 0.4 0.00073 19.8 0.4 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_20 PF00728.22 EER29225.1 - 3.3e-100 335.9 0.7 4.1e-100 335.6 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EER29225.1 - 1.2e-25 90.8 0.0 2.4e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EER29225.1 - 0.00029 21.6 0.0 0.00064 20.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DNA_pol_lambd_f PF10391.9 EER29225.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda DOCK_N PF16172.5 EER29226.1 - 9.2e-115 383.6 0.0 1.7e-114 382.7 0.0 1.5 1 0 0 1 1 1 1 DOCK N-terminus DHR-2 PF06920.13 EER29226.1 - 1.4e-38 132.9 6.6 4.7e-38 131.1 6.6 1.7 1 1 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EER29226.1 - 2.4e-38 131.9 0.0 4.9e-38 130.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 EER29226.1 - 0.00017 21.1 0.0 0.0004 19.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER29226.1 - 0.00042 20.1 0.2 0.0067 16.3 0.0 2.7 3 0 0 3 3 3 1 Variant SH3 domain Sec3-PIP2_bind PF15277.6 EER29227.1 - 1.4e-28 98.8 0.0 2.5e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.9 EER29227.1 - 4.2e-27 94.9 1.5 6.2e-27 94.3 1.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3_C_2 PF15278.6 EER29227.1 - 0.00045 20.5 0.0 0.00083 19.7 0.0 1.4 1 0 0 1 1 1 1 Sec3 exocyst complex subunit SRP40_C PF05022.12 EER29228.1 - 1.4e-16 61.1 0.3 1.4e-16 61.1 0.3 2.2 2 0 0 2 2 2 1 SRP40, C-terminal domain F-box-like PF12937.7 EER29229.1 - 3.8e-07 29.9 0.4 1.4e-06 28.1 0.4 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EER29229.1 - 9.8e-05 22.1 0.3 0.00022 21.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EER29229.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 F-box p450 PF00067.22 EER29230.1 - 1.7e-54 185.4 0.0 2.4e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAM193_C PF15914.5 EER29231.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 FAM193 family C-terminal CHCH PF06747.13 EER29231.1 - 0.022 14.9 1.2 0.041 14.0 0.9 1.6 1 1 1 2 2 2 0 CHCH domain Cmc1 PF08583.10 EER29231.1 - 0.057 13.5 0.9 0.074 13.1 0.9 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EER29231.1 - 0.061 13.4 1.8 0.099 12.7 1.5 1.5 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF1992 PF09350.10 EER29232.1 - 1.5e-22 79.5 0.4 5.1e-22 77.8 0.4 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.10 EER29232.1 - 0.27 11.0 3.2 0.46 10.3 0.0 2.8 2 0 0 2 2 2 0 RPAP1-like, N-terminal SCP1201-deam PF14428.6 EER29232.1 - 7.2 6.5 8.3 1.4 8.8 1.1 2.6 2 1 0 2 2 2 0 SCP1.201-like deaminase adh_short_C2 PF13561.6 EER29234.1 - 1.5e-54 185.0 2.0 1.8e-54 184.8 2.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER29234.1 - 1e-44 152.3 1.4 1.3e-44 152.0 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER29234.1 - 2.8e-07 30.6 0.8 5.1e-07 29.8 0.8 1.5 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.18 EER29234.1 - 7.5e-07 29.4 0.5 1.6e-06 28.4 0.5 1.5 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EER29234.1 - 2e-05 24.9 0.6 3.6e-05 24.0 0.6 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EER29234.1 - 3.5e-05 23.0 0.4 4.7e-05 22.5 0.4 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EER29234.1 - 4.6e-05 23.0 0.7 0.00017 21.2 0.4 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EER29234.1 - 0.0002 20.6 0.2 0.00029 20.1 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EER29234.1 - 0.00024 21.0 1.5 0.00038 20.4 1.5 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EER29234.1 - 0.00082 18.9 0.7 0.0025 17.3 0.2 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase UDPG_MGDP_dh_N PF03721.14 EER29234.1 - 0.0023 17.6 0.3 0.0044 16.6 0.2 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EER29234.1 - 0.0041 17.7 0.2 0.0084 16.7 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Methyltransf_31 PF13847.6 EER29234.1 - 0.0047 16.7 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.6 EER29234.1 - 0.0056 16.6 0.4 0.0083 16.0 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Methyltransf_25 PF13649.6 EER29234.1 - 0.011 16.5 0.3 0.035 14.8 0.2 1.9 1 1 1 2 2 2 0 Methyltransferase domain Ldh_1_N PF00056.23 EER29234.1 - 0.034 14.2 0.8 0.067 13.3 0.8 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 EER29234.1 - 0.048 13.3 0.1 0.08 12.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XAF1_C PF18608.1 EER29236.1 - 0.012 15.1 0.1 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain Acetyltransf_8 PF13523.6 EER29238.1 - 1.6e-45 154.3 0.0 2.2e-45 153.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L15e PF00827.17 EER29239.1 - 8.1e-91 302.9 9.9 9.9e-91 302.6 9.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 Hepatitis_core PF00906.20 EER29239.1 - 0.048 13.2 0.3 0.048 13.2 0.3 2.0 2 0 0 2 2 2 0 Hepatitis core antigen CHD5 PF04420.14 EER29240.1 - 0.043 13.7 1.0 0.077 12.9 1.0 1.3 1 0 0 1 1 1 0 CHD5-like protein PSP1 PF04468.12 EER29241.1 - 1.1e-27 96.2 3.3 1.8e-27 95.4 3.3 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.11 EER29242.1 - 9.7e-28 96.1 0.0 3.7e-27 94.2 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EER29242.1 - 1.3e-27 95.7 0.0 2.2e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 EER29242.1 - 0.017 15.2 0.1 0.038 14.1 0.1 1.6 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus RasGEF PF00617.19 EER29243.1 - 3e-45 154.6 0.2 9.1e-45 153.0 0.2 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EER29243.1 - 7.9e-11 42.1 0.0 2e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.22 EER29243.1 - 0.0017 17.9 0.0 0.0081 15.8 0.0 2.1 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.6 EER29243.1 - 0.012 16.0 1.4 0.24 11.8 1.4 2.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EER29243.1 - 0.11 12.7 0.1 0.54 10.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EER29243.1 - 0.16 12.1 0.0 0.46 10.6 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EER29243.1 - 0.16 12.5 0.2 0.83 10.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter zf-HIT PF04438.16 EER29244.1 - 5.9e-09 35.6 8.0 1e-08 34.9 8.0 1.4 1 0 0 1 1 1 1 HIT zinc finger C1_2 PF03107.16 EER29244.1 - 0.19 12.0 6.1 0.57 10.5 6.4 1.7 2 0 0 2 2 2 0 C1 domain Complex1_LYR_2 PF13233.6 EER29245.1 - 2.1e-21 76.4 0.6 2.7e-21 76.1 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Cyclin_N PF00134.23 EER29246.1 - 1.7e-11 44.0 0.0 3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EER29246.1 - 7.6e-05 23.1 0.0 0.00018 21.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin Pkinase PF00069.25 EER29247.1 - 8.7e-11 41.7 1.0 2e-09 37.2 1.0 2.1 1 1 0 1 1 1 1 Protein kinase domain MFS_1 PF07690.16 EER29249.1 - 2.9e-25 89.0 39.3 2.9e-25 89.0 39.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3810 PF12725.7 EER29249.1 - 0.14 11.5 0.2 2.4 7.4 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) SBF PF01758.16 EER29250.1 - 9.5e-53 178.8 10.4 9.5e-53 178.8 10.4 2.3 2 1 1 3 3 3 1 Sodium Bile acid symporter family ATP_bind_3 PF01171.20 EER29251.1 - 7.9e-19 68.1 0.0 1.5e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 EER29251.1 - 8.9e-18 63.5 4.5 8.9e-18 63.5 4.5 3.7 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 EER29251.1 - 0.006 15.4 0.0 0.009 14.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.15 EER29251.1 - 0.012 15.1 1.1 0.012 15.1 1.1 2.9 3 0 0 3 3 3 0 RecR protein zf-UBR PF02207.20 EER29251.1 - 0.47 10.6 5.5 6.8 6.9 0.4 2.7 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) zf-C3HC4_5 PF17121.5 EER29251.1 - 0.96 9.4 4.0 0.29 11.0 0.8 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HECT PF00632.25 EER29252.1 - 2.9e-72 243.8 0.0 3.9e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ADH_N PF08240.12 EER29253.1 - 2.6e-35 120.6 4.1 3.7e-35 120.1 2.6 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER29253.1 - 1.3e-15 57.6 0.0 2.1e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EER29253.1 - 8.5e-11 41.7 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EER29253.1 - 9.7e-07 29.9 0.0 1.6e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 EER29253.1 - 0.031 13.5 0.6 0.046 13.0 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_3 PF03447.16 EER29253.1 - 0.082 13.6 0.0 0.49 11.1 0.0 2.1 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Staph_opine_DH PF10100.9 EER29253.1 - 0.21 10.2 0.0 0.27 9.8 0.0 1.1 1 0 0 1 1 1 0 Staphylopine dehydrogenase FRG1 PF06229.12 EER29254.1 - 3e-55 186.9 0.1 4.2e-55 186.4 0.1 1.2 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EER29254.1 - 0.0079 16.4 0.0 0.062 13.5 0.0 2.2 2 0 0 2 2 2 1 Fascin domain zf-RING_2 PF13639.6 EER29255.1 - 8.8e-13 48.4 5.3 1.7e-12 47.4 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EER29255.1 - 1.6e-08 34.1 3.8 4.4e-08 32.7 3.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EER29255.1 - 5.9e-08 32.4 5.1 1.3e-07 31.4 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EER29255.1 - 1.8e-06 27.8 3.1 3.4e-06 26.9 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EER29255.1 - 1.5e-05 24.7 4.4 2.8e-05 23.9 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EER29255.1 - 1.7e-05 24.8 2.4 1.7e-05 24.8 2.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EER29255.1 - 0.00045 20.5 7.2 0.0022 18.2 7.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EER29255.1 - 0.0012 18.7 2.7 0.0024 17.7 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EER29255.1 - 0.0026 17.8 1.7 0.0053 16.8 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EER29255.1 - 0.0097 15.7 10.4 0.35 10.8 10.1 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EER29255.1 - 0.04 13.5 1.6 0.081 12.6 1.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 EER29255.1 - 0.18 12.0 0.2 0.38 10.9 0.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-Nse PF11789.8 EER29255.1 - 0.22 11.4 3.9 0.58 10.0 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EER29255.1 - 0.27 11.4 5.8 0.7 10.1 5.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EER29255.1 - 0.37 11.1 3.6 1 9.7 3.5 1.9 1 1 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EER29255.1 - 0.57 10.0 2.6 1.2 9.0 2.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EER29255.1 - 0.64 10.0 2.7 1.3 9.0 2.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-P11 PF03854.14 EER29255.1 - 1.3 8.7 4.5 0.31 10.7 0.8 1.8 2 0 0 2 2 2 0 P-11 zinc finger Ada3 PF10198.9 EER29256.1 - 5.5e-51 172.1 0.0 1.2e-50 171.1 0.0 1.6 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 Sporozoite_P67 PF05642.11 EER29256.1 - 1.1 7.2 6.9 4.1 5.4 2.3 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NPR2 PF06218.11 EER29257.1 - 1.4e-138 462.4 0.0 1.6e-137 458.8 0.0 2.3 1 1 0 1 1 1 1 Nitrogen permease regulator 2 Fungal_trans PF04082.18 EER29258.1 - 5.9e-12 45.2 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29258.1 - 1e-05 25.5 10.7 2.4e-05 24.4 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EER29258.1 - 0.00028 21.4 18.0 0.12 13.2 6.5 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EER29258.1 - 0.0056 17.1 24.3 0.045 14.2 8.4 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER29258.1 - 0.0087 16.4 12.6 0.035 14.6 7.1 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EER29258.1 - 0.023 15.0 5.0 0.19 12.0 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding p450 PF00067.22 EER29259.1 - 6.7e-75 252.6 0.0 8.3e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B_2 PF12706.7 EER29261.1 - 6.5e-10 38.9 0.0 1.3e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 EER29261.1 - 2.6e-06 27.6 0.1 9.4e-06 25.8 0.1 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 EER29261.1 - 9.5e-06 25.7 0.0 1.8e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Amidohydro_1 PF01979.20 EER29262.1 - 5.7e-76 256.1 0.6 1e-75 255.2 0.6 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 EER29262.1 - 3.7e-55 185.4 1.5 3.7e-55 185.4 1.5 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EER29262.1 - 4e-41 139.0 0.1 3.9e-40 135.8 0.0 2.3 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 EER29262.1 - 1.1e-38 131.5 0.2 2.5e-38 130.4 0.2 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EER29262.1 - 5.2e-11 42.7 0.2 3.5e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family HMG_box PF00505.19 EER29263.1 - 3.3e-08 33.8 3.6 3.3e-08 33.8 3.6 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EER29263.1 - 1.9e-05 25.2 3.1 1.9e-05 25.2 3.1 2.1 2 0 0 2 2 2 1 HMG-box domain NAD_binding_1 PF00175.21 EER29264.1 - 3.2e-33 114.6 0.0 5.4e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EER29264.1 - 1.1e-23 83.4 0.0 2.2e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EER29264.1 - 5.7e-10 39.5 0.0 1.2e-05 25.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EER29264.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Ribosomal_L18A PF01775.17 EER29265.1 - 5.1e-45 152.5 2.5 6.3e-45 152.2 2.5 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 EER29266.1 - 4e-06 27.3 0.0 0.00063 20.2 0.0 2.7 3 0 0 3 3 3 2 PCI domain BTB PF00651.31 EER29267.1 - 8.4e-06 26.0 0.0 3.6e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain DUF434 PF04256.12 EER29267.1 - 0.089 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF434) tRNA-synt_2 PF00152.20 EER29268.1 - 5.8e-70 235.8 0.0 7.4e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EER29268.1 - 3.3e-10 39.8 0.0 5.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EER29268.1 - 1.3e-06 28.1 0.2 0.021 14.3 0.0 3.6 4 0 0 4 4 4 2 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 EER29269.1 - 1.2e-21 76.1 1.1 1.4e-21 75.9 1.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PG_binding_1 PF01471.18 EER29270.1 - 0.052 13.8 0.0 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Spc7 PF08317.11 EER29270.1 - 0.17 10.7 3.2 0.32 9.8 3.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 EER29270.1 - 0.93 10.0 7.5 2.4 8.7 7.5 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-F_N PF10481.9 EER29270.1 - 1.9 8.0 6.5 0.2 11.3 1.8 1.7 2 0 0 2 2 2 0 Cenp-F N-terminal domain CLTH PF10607.9 EER29271.1 - 3.3e-35 121.1 0.0 5.7e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EER29271.1 - 6.9e-08 32.4 0.1 1.3e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EER29271.1 - 0.0008 19.3 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Rtf2 PF04641.12 EER29271.1 - 0.00093 18.6 0.5 0.0015 18.0 0.1 1.5 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.6 EER29271.1 - 0.0025 18.1 0.3 0.0049 17.2 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EER29271.1 - 0.0076 16.1 0.8 0.015 15.1 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EER29271.1 - 0.061 13.2 0.5 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EER29271.1 - 0.072 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EER29271.1 - 0.093 12.6 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SAD_SRA PF02182.17 EER29272.1 - 1.1e-27 96.7 0.1 1.7e-27 96.0 0.1 1.3 1 0 0 1 1 1 1 SAD/SRA domain 2OG-FeII_Oxy PF03171.20 EER29273.1 - 3.7e-05 24.1 0.0 8e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EER29273.1 - 0.019 15.7 0.0 0.049 14.4 0.0 1.7 2 0 0 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal p450 PF00067.22 EER29274.1 - 3.8e-75 253.4 0.0 4.9e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Clr2 PF10383.9 EER29275.1 - 7.8e-32 111.1 0.0 3.4e-31 109.0 0.0 2.1 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 p450 PF00067.22 EER29276.1 - 1.2e-19 70.4 0.4 1.1e-18 67.3 0.0 2.5 3 1 0 3 3 3 1 Cytochrome P450 ABC_membrane_2 PF06472.15 EER29277.1 - 3e-89 299.0 0.1 5.6e-89 298.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EER29277.1 - 3e-13 50.5 0.0 7.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EER29277.1 - 0.011 15.5 0.0 0.76 9.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EER29277.1 - 0.022 15.1 0.1 0.059 13.8 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EER29277.1 - 0.026 15.0 0.1 0.086 13.3 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EER29277.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ALIX_LYPXL_bnd PF13949.6 EER29277.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Mg_chelatase PF01078.21 EER29277.1 - 0.16 11.3 0.5 0.31 10.4 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NIF PF03031.18 EER29278.1 - 6.3e-55 185.2 0.3 8.5e-55 184.8 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.7 EER29279.1 - 2.5e-30 104.0 54.3 2.2e-08 34.3 3.1 6.8 2 2 6 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EER29279.1 - 7.5e-22 76.9 39.2 6.9e-07 28.9 3.9 5.4 4 1 1 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EER29279.1 - 5.6e-12 45.5 13.7 3.6e-06 26.6 1.4 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 EER29279.1 - 0.0015 18.8 26.9 3.4 8.6 0.8 8.4 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 EER29279.1 - 0.024 14.7 34.9 0.053 13.6 0.9 8.2 8 0 0 8 8 8 0 Leucine Rich repeat Kelch_4 PF13418.6 EER29279.1 - 0.071 13.1 0.3 0.41 10.7 0.0 2.2 2 0 0 2 2 2 0 Galactose oxidase, central domain Pkip-1 PF06878.11 EER29279.1 - 0.7 10.0 7.4 0.69 10.0 0.2 2.8 3 1 0 3 3 3 0 Pkip-1 protein Aldo_ket_red PF00248.21 EER29281.1 - 3.7e-40 137.9 0.0 4.5e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family zinc_ribbon_15 PF17032.5 EER29282.1 - 0.0025 18.5 3.6 0.0038 18.0 3.6 1.3 1 0 0 1 1 1 1 zinc-ribbon family RecR PF02132.15 EER29282.1 - 0.036 13.6 1.7 0.83 9.3 0.1 2.3 2 0 0 2 2 2 0 RecR protein PriA_CRR PF18319.1 EER29282.1 - 0.12 12.4 0.3 0.12 12.4 0.3 2.3 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Dynein_light PF01221.18 EER29283.1 - 1.6e-40 137.3 2.9 1.8e-40 137.1 2.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ribosomal_L6e PF01159.19 EER29283.1 - 0.079 13.5 1.1 0.095 13.2 1.1 1.1 1 0 0 1 1 1 0 Ribosomal protein L6e Peptidase_M24 PF00557.24 EER29283.1 - 0.11 12.2 0.1 0.12 12.0 0.1 1.0 1 0 0 1 1 1 0 Metallopeptidase family M24 RRM_1 PF00076.22 EER29284.1 - 4.7e-71 234.6 1.4 4.2e-18 64.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER29284.1 - 1.7e-06 27.6 0.1 0.0082 15.7 0.0 4.5 4 1 1 5 5 5 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EER29284.1 - 2.2e-06 27.5 0.0 0.032 14.2 0.0 3.7 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EER29284.1 - 1.1e-05 25.5 0.0 0.44 10.7 0.0 3.9 3 0 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 EER29284.1 - 0.00019 21.2 0.0 11 5.9 0.0 5.5 6 0 0 6 6 6 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EER29284.1 - 0.0028 17.7 0.1 3.3 7.8 0.0 4.7 5 0 0 5 5 5 1 Limkain b1 RRM_Rrp7 PF17799.1 EER29284.1 - 0.0062 16.3 0.2 13 5.6 0.0 4.3 4 0 0 4 4 4 1 Rrp7 RRM-like N-terminal domain RRM_2 PF04059.12 EER29284.1 - 0.012 15.8 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif 2 DUF4523 PF15023.6 EER29284.1 - 0.029 14.2 1.5 1.4 8.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) WW_like PF17890.1 EER29284.1 - 0.078 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain Sec61_beta PF03911.16 EER29285.1 - 7.6e-18 64.3 1.0 1e-17 63.8 1.0 1.2 1 0 0 1 1 1 1 Sec61beta family DUF1129 PF06570.11 EER29286.1 - 2.6 7.5 12.4 0.079 12.4 4.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) MIG-14_Wnt-bd PF06664.12 EER29286.1 - 8.8 5.4 30.7 0.04 13.1 7.2 3.4 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion PCNA_N PF00705.18 EER29287.1 - 4.1e-55 184.9 4.1 4.4e-55 184.8 2.8 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EER29287.1 - 1.3e-50 170.9 0.1 4.6e-50 169.1 0.0 1.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EER29287.1 - 1.4e-07 31.3 0.1 1.7e-07 31.0 0.1 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 EER29287.1 - 0.0043 16.2 0.4 0.014 14.6 0.1 1.9 1 1 1 2 2 2 1 Hus1-like protein Vezatin PF12632.7 EER29288.1 - 1.3e-77 261.0 0.3 1.3e-77 261.0 0.3 1.5 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes Polysacc_synt_C PF14667.6 EER29288.1 - 0.11 12.5 1.1 0.22 11.6 1.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF2628 PF10947.8 EER29288.1 - 0.8 10.1 5.3 1.3 9.4 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) Metallophos PF00149.28 EER29289.1 - 2.4e-40 139.2 0.1 3.1e-40 138.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EER29289.1 - 1.2e-22 80.1 2.6 1.5e-22 79.8 1.7 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Arf PF00025.21 EER29290.1 - 1.6e-60 203.6 0.0 1.7e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EER29290.1 - 2.7e-09 36.7 0.2 3e-05 23.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EER29290.1 - 4.1e-07 30.1 0.0 5.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EER29290.1 - 8e-07 28.7 0.0 1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EER29290.1 - 1.8e-05 25.0 0.0 4.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EER29290.1 - 0.00039 20.0 0.0 0.00054 19.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EER29290.1 - 0.0047 16.3 0.0 0.0057 16.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CENP-M PF11111.8 EER29290.1 - 0.017 14.3 0.0 0.045 13.0 0.0 1.6 2 0 0 2 2 2 0 Centromere protein M (CENP-M) RsgA_GTPase PF03193.16 EER29290.1 - 0.045 13.7 0.2 0.45 10.4 0.1 2.1 2 1 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 EER29290.1 - 0.14 11.7 0.0 3.1 7.3 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF2457 PF10446.9 EER29291.1 - 2.9e-161 537.7 29.9 2.9e-161 537.7 29.9 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 EER29291.1 - 0.11 12.5 15.3 0.25 11.3 15.3 1.8 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CH PF00307.31 EER29293.1 - 3e-07 30.6 0.0 3.5e-05 23.9 0.0 2.8 2 1 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 EER29293.1 - 0.064 13.1 0.4 0.17 11.8 0.4 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif LRR_8 PF13855.6 EER29294.1 - 2.7e-11 43.0 4.4 3.6e-06 26.6 0.9 3.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 EER29294.1 - 2.8e-07 30.7 4.9 0.0033 17.8 0.1 4.0 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EER29294.1 - 0.00018 21.6 5.0 6.7 7.7 0.1 5.3 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 EER29294.1 - 0.0026 17.7 7.2 2 8.7 0.1 4.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 EER29294.1 - 0.012 15.1 0.1 0.051 13.1 0.1 2.0 1 1 1 2 2 2 0 Leucine-rich repeat DUF3336 PF11815.8 EER29295.1 - 2.5e-47 160.1 0.5 3.8e-47 159.5 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EER29295.1 - 2.2e-18 67.2 0.1 4.4e-17 62.9 0.1 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1206 PF06724.11 EER29295.1 - 0.081 13.0 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) TPR_19 PF14559.6 EER29296.1 - 1.4e-21 76.8 15.1 9.7e-09 35.6 0.0 7.3 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EER29296.1 - 3.7e-15 55.3 13.3 0.014 16.2 0.6 7.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EER29296.1 - 1.3e-11 43.9 15.3 0.00012 21.7 0.2 7.3 7 3 2 9 9 9 2 TPR repeat TPR_17 PF13431.6 EER29296.1 - 6.1e-11 41.9 7.6 1.1 9.8 0.0 8.6 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 EER29296.1 - 3.1e-10 39.4 30.7 0.094 12.9 0.1 10.4 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EER29296.1 - 8.4e-09 35.9 13.7 0.0033 18.1 0.1 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EER29296.1 - 3.3e-07 29.8 2.9 3 8.1 0.0 7.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 EER29296.1 - 8.9e-07 28.5 18.1 0.52 10.2 0.0 9.0 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER29296.1 - 0.00012 22.0 26.4 0.13 12.6 0.1 9.5 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_20 PF14561.6 EER29296.1 - 0.00033 20.9 9.4 2.9 8.3 0.1 5.3 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EER29296.1 - 0.00091 18.7 4.8 0.92 8.8 0.0 4.5 4 1 0 4 4 4 1 MalT-like TPR region ANAPC3 PF12895.7 EER29296.1 - 0.0013 18.9 23.1 0.036 14.3 0.0 6.6 7 0 0 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 EER29296.1 - 0.008 15.1 4.6 0.66 8.8 1.0 3.3 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 RPN7 PF10602.9 EER29296.1 - 0.0089 15.7 3.0 3.4 7.4 0.1 4.1 4 1 0 4 4 4 1 26S proteasome subunit RPN7 BTAD PF03704.17 EER29296.1 - 0.017 15.6 0.5 0.017 15.6 0.5 3.0 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 EER29296.1 - 0.019 15.1 15.1 0.12 12.6 1.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EER29296.1 - 0.045 14.4 12.5 2.4 9.0 0.1 6.2 6 0 0 6 6 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EER29296.1 - 0.12 11.3 0.4 0.33 9.9 0.0 1.8 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) SNAP PF14938.6 EER29296.1 - 0.43 10.0 5.9 2.2 7.6 0.0 3.2 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_15 PF13429.6 EER29296.1 - 0.68 9.1 9.8 1.7 7.8 0.2 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER29296.1 - 4 7.8 25.3 3.7 7.9 0.0 7.9 7 3 1 8 8 8 0 Tetratricopeptide repeat SAM_2 PF07647.17 EER29297.1 - 1.4e-08 34.7 0.2 2.6e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EER29297.1 - 0.00087 19.7 0.2 0.0016 18.8 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 EER29297.1 - 0.047 13.9 0.4 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) Rab5ip PF07019.12 EER29298.1 - 3.3e-22 78.9 7.2 4.3e-22 78.5 7.2 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) GPI2 PF06432.11 EER29298.1 - 0.13 11.7 0.1 0.16 11.4 0.1 1.0 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase MFS_1 PF07690.16 EER29299.1 - 8.8e-25 87.4 61.7 6.1e-23 81.3 56.0 3.5 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER29299.1 - 1.3e-12 47.0 13.3 1.3e-12 47.0 13.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sulfate_transp PF00916.20 EER29301.1 - 3.1e-108 361.9 13.2 4.6e-108 361.4 13.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EER29301.1 - 7.9e-08 32.0 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EER29301.1 - 0.0071 16.7 15.8 0.0091 16.4 1.5 3.2 2 2 1 3 3 3 2 Molybdate transporter of MFS superfamily DUF1772 PF08592.11 EER29301.1 - 0.29 11.4 5.2 0.25 11.6 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DnaJ_C PF01556.18 EER29302.1 - 8.6e-39 133.0 0.1 1.2e-38 132.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EER29302.1 - 1.1e-25 89.5 2.6 1.9e-25 88.8 2.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EER29302.1 - 1.6e-16 60.4 17.3 2.7e-16 59.7 17.3 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EER29302.1 - 0.84 9.7 8.7 1.6 8.8 2.1 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 EER29302.1 - 2.9 7.9 6.1 2.7 8.1 0.9 2.2 1 1 1 2 2 2 0 zinc-ribbons Anti-TRAP PF15777.5 EER29302.1 - 3.1 7.8 17.3 0.21 11.5 2.5 2.9 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2614 PF11023.8 EER29302.1 - 3.6 7.7 5.3 12 6.0 0.7 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain URO-D PF01208.17 EER29303.1 - 2.1e-129 431.6 0.0 2.4e-129 431.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) CPSF_A PF03178.15 EER29304.1 - 0.17 11.1 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region WD40 PF00400.32 EER29304.1 - 0.31 12.0 6.3 3.8 8.5 1.6 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Ribosomal_L10 PF00466.20 EER29305.1 - 4.7e-24 84.4 0.3 1.4e-23 82.9 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EER29305.1 - 3.4e-22 78.2 0.0 6.9e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EER29305.1 - 1.9e-16 60.4 3.5 1.9e-16 60.4 3.5 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein WRNPLPNID PF15017.6 EER29305.1 - 0.066 14.1 1.7 0.13 13.2 1.7 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Vps53_N PF04100.12 EER29306.1 - 7.7e-106 354.2 10.5 1.4e-105 353.4 10.5 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2451 PF10474.9 EER29306.1 - 5.5e-06 26.3 0.1 5.5e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 EER29306.1 - 3.8e-05 23.1 9.8 3.8e-05 23.1 9.8 2.0 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DegV PF02645.16 EER29306.1 - 0.066 12.5 3.8 0.079 12.3 0.1 2.5 2 1 1 3 3 3 0 Uncharacterised protein, DegV family COG1307 Gemini_AL1_M PF08283.11 EER29306.1 - 0.14 12.2 0.0 0.61 10.2 0.0 2.1 1 0 0 1 1 1 0 Geminivirus rep protein central domain DUF1515 PF07439.11 EER29306.1 - 0.44 10.6 8.7 0.065 13.3 2.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) COG2 PF06148.11 EER29306.1 - 0.52 10.4 7.1 0.3 11.2 3.9 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Sigma70_ner PF04546.13 EER29306.1 - 0.78 9.6 10.9 20 5.0 9.7 3.1 2 1 0 2 2 2 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.11 EER29306.1 - 1.6 6.7 6.7 2.5 6.1 6.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YabA PF06156.13 EER29306.1 - 3.5 8.3 5.6 8.4 7.1 4.1 2.6 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 EER29306.1 - 4.7 7.8 11.3 10 6.6 10.1 2.3 1 1 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 EER29306.1 - 5.9 7.2 8.5 0.78 10.0 2.6 2.8 3 0 0 3 3 3 0 Haemolysin XhlA TAP_C PF03943.13 EER29307.1 - 2e-18 65.7 1.8 3.2e-18 65.1 1.0 1.8 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 EER29307.1 - 2.8e-05 24.4 7.5 0.0018 18.6 0.9 2.9 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) RRM_9 PF18444.1 EER29307.1 - 3.2e-05 23.7 0.0 9e-05 22.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif LRR_8 PF13855.6 EER29307.1 - 9.7e-05 22.1 0.6 0.00025 20.7 0.6 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 EER29307.1 - 0.001 18.6 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat NTF2 PF02136.20 EER29307.1 - 0.0021 18.6 0.0 0.0048 17.5 0.0 1.6 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain COPIIcoated_ERV PF07970.12 EER29308.1 - 6.2e-83 278.0 0.0 8.9e-83 277.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EER29308.1 - 6.7e-30 103.3 0.0 3.8e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PH PF00169.29 EER29309.1 - 5.2e-06 26.9 0.0 6e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 EER29309.1 - 0.0014 19.0 0.0 0.0064 16.9 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain zf-C2H2 PF00096.26 EER29310.1 - 1.5e-24 85.0 62.7 4.7e-05 23.6 0.6 11.5 10 2 1 11 11 11 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER29310.1 - 1.2e-17 63.0 60.9 0.0074 17.0 0.5 11.3 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EER29310.1 - 3.4e-13 49.4 54.2 0.00024 21.4 0.5 10.9 11 0 0 11 11 11 6 Zinc-finger double domain zf-C2H2_11 PF16622.5 EER29310.1 - 6.8e-07 28.9 12.8 0.053 13.3 0.3 5.7 5 0 0 5 5 5 3 zinc-finger C2H2-type FOXP-CC PF16159.5 EER29310.1 - 9.5e-07 29.4 26.1 0.2 12.3 0.0 8.7 5 2 4 9 9 9 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EER29310.1 - 5.7e-06 26.5 15.8 3.5 8.0 0.0 8.5 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 EER29310.1 - 2.7e-05 23.9 1.4 2.7e-05 23.9 1.4 3.2 4 0 0 4 4 4 1 GAGA factor zf-C2H2_8 PF15909.5 EER29310.1 - 0.0018 18.5 20.7 0.11 12.8 0.9 4.3 4 1 2 6 6 6 3 C2H2-type zinc ribbon zf-H2C2_5 PF13909.6 EER29310.1 - 0.054 13.3 0.6 0.054 13.3 0.6 9.2 9 0 0 9 9 8 0 C2H2-type zinc-finger domain zf-met PF12874.7 EER29310.1 - 0.077 13.4 13.7 20 5.7 0.0 7.6 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 EER29310.1 - 0.13 12.4 21.5 0.18 11.9 0.4 5.4 5 1 2 7 7 6 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 EER29310.1 - 0.3 11.1 0.1 0.3 11.1 0.1 9.3 11 0 0 11 11 11 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 EER29310.1 - 0.36 10.7 5.6 22 5.0 0.2 3.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 EER29310.1 - 0.87 10.3 17.4 21 5.8 1.3 5.5 1 1 5 6 6 6 0 Zinc finger C2H2-type, 3 repeats RNA_pol_Rpb6 PF01192.22 EER29311.1 - 5.7e-17 61.4 0.1 8.4e-17 60.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 MFS_1 PF07690.16 EER29312.1 - 2.5e-22 79.3 49.1 3.9e-17 62.2 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hum_adeno_E3A PF05393.11 EER29312.1 - 0.13 12.2 1.1 0.27 11.2 0.2 1.9 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein Acetyltransf_1 PF00583.25 EER29313.1 - 6.9e-12 45.6 0.0 9.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EER29313.1 - 3.4e-09 36.7 0.0 6.3e-09 35.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EER29313.1 - 6.3e-08 32.9 0.1 1e-07 32.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER29313.1 - 1.7e-06 27.9 0.0 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EER29313.1 - 0.016 15.3 0.2 0.024 14.7 0.2 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATG16 PF08614.11 EER29314.1 - 0.00063 20.0 0.4 0.0011 19.2 0.4 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) PCI PF01399.27 EER29315.1 - 1.1e-12 48.4 0.6 5.6e-11 42.9 0.0 3.3 2 0 0 2 2 2 1 PCI domain Vps4_C PF09336.10 EER29315.1 - 0.11 12.5 1.4 1.2 9.2 0.2 3.0 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain G-gamma PF00631.22 EER29316.1 - 2.9e-23 81.7 0.0 3.5e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain Rdx PF10262.9 EER29317.1 - 1.8e-33 114.6 0.0 2.4e-33 114.1 0.0 1.2 1 0 0 1 1 1 1 Rdx family PDEase_I PF00233.19 EER29318.1 - 6.8e-68 228.9 0.0 1e-67 228.3 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DEAD PF00270.29 EER29319.1 - 3.6e-17 62.7 0.1 9.4e-17 61.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER29319.1 - 1.2e-07 32.0 0.0 4.6e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER29319.1 - 2.5e-07 30.9 0.0 4.7e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.6 EER29319.1 - 0.017 15.7 0.1 0.077 13.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain FAD_binding_4 PF01565.23 EER29320.1 - 3e-28 98.3 0.0 6.8e-28 97.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain FAD-oxidase_C PF02913.19 EER29320.1 - 4.8e-15 55.9 0.0 7.3e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Sugar_tr PF00083.24 EER29321.1 - 4.1e-81 273.2 24.7 4.9e-81 272.9 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER29321.1 - 3.6e-16 59.0 25.7 3.6e-16 59.0 25.7 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily p450 PF00067.22 EER29322.1 - 2.2e-57 194.9 0.0 1.6e-54 185.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EER29323.1 - 4.3e-16 58.8 0.0 7.2e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPE65 PF03055.15 EER29324.1 - 1.1e-100 338.0 0.0 1.3e-100 337.8 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein FMO-like PF00743.19 EER29325.1 - 5.1e-16 58.2 0.0 6.4e-11 41.4 0.1 3.0 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EER29325.1 - 1.9e-10 40.4 0.0 8.2e-05 22.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER29325.1 - 6.8e-10 39.0 0.0 6.8e-10 39.0 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EER29325.1 - 2.3e-08 33.7 0.9 0.00072 18.9 0.2 3.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EER29325.1 - 8.3e-08 32.2 1.9 0.031 13.9 0.1 3.4 2 1 1 3 3 3 3 FAD dependent oxidoreductase K_oxygenase PF13434.6 EER29325.1 - 5.5e-06 25.8 0.1 0.0008 18.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 EER29325.1 - 0.0002 20.6 3.4 0.0075 15.4 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.17 EER29325.1 - 0.00046 19.5 0.4 0.082 12.1 0.0 3.2 3 0 0 3 3 3 1 Thi4 family NAD_binding_9 PF13454.6 EER29325.1 - 0.0018 18.3 0.6 4.4 7.3 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 EER29325.1 - 0.042 14.4 0.5 3.3 8.3 0.3 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EER29325.1 - 0.044 12.3 0.1 2.9 6.3 0.1 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) NAD_binding_4 PF07993.12 EER29326.1 - 1.2e-38 132.8 0.0 2e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EER29326.1 - 4.8e-32 111.1 0.0 7.7e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EER29326.1 - 4.4e-13 49.3 0.0 9e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EER29326.1 - 4.1e-09 36.7 0.0 9.4e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EER29326.1 - 3.8e-05 22.8 0.0 0.00015 20.9 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EER29326.1 - 4.6e-05 23.0 0.1 0.00013 21.5 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EER29326.1 - 0.0073 16.2 0.2 0.059 13.3 0.2 2.3 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EER29326.1 - 0.01 15.4 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 EER29326.1 - 0.026 13.7 0.4 0.083 12.0 0.2 2.0 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EER29326.1 - 0.048 13.5 0.1 0.1 12.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 EER29326.1 - 0.19 11.8 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FAA_hydrolase PF01557.18 EER29327.1 - 1.5e-48 165.3 0.0 1.8e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family H_PPase PF03030.16 EER29327.1 - 0.17 10.5 0.1 0.24 10.0 0.1 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Glyoxalase PF00903.25 EER29328.1 - 2.4e-12 47.2 3.3 2.4e-10 40.7 0.6 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1824 PF08854.10 EER29328.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) FAD_binding_3 PF01494.19 EER29329.1 - 1.3e-18 67.4 0.0 2.8e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain zf-HC5HC2H_2 PF13832.6 EER29330.1 - 7.9e-23 80.7 2.0 7.9e-23 80.7 2.0 4.0 3 1 0 3 3 3 2 PHD-zinc-finger like domain BAH PF01426.18 EER29330.1 - 2.6e-18 66.0 0.0 5e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 EER29330.1 - 2.9e-18 65.9 3.3 2.9e-18 65.9 3.3 4.7 4 0 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 EER29330.1 - 4.1e-11 42.6 50.5 9.4e-07 28.6 6.8 5.8 6 0 0 6 6 6 2 PHD-finger PHD_2 PF13831.6 EER29330.1 - 2.5e-08 33.3 4.3 2.5e-08 33.3 4.3 4.9 6 0 0 6 6 6 1 PHD-finger C1_1 PF00130.22 EER29330.1 - 0.004 17.0 3.2 0.004 17.0 3.2 7.4 7 1 1 8 8 8 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Myb_DNA-binding PF00249.31 EER29330.1 - 0.0064 16.7 0.1 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain ELM2 PF01448.24 EER29330.1 - 1.2 10.0 4.4 9.4 7.1 1.1 3.5 3 1 0 3 3 3 0 ELM2 domain Zf_RING PF16744.5 EER29330.1 - 2.5 8.3 38.0 0.039 14.1 5.3 5.4 5 1 0 5 5 5 0 KIAA1045 RING finger Glucosamine_iso PF01182.20 EER29331.1 - 1.1e-68 231.5 0.0 1.2e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NAGLU PF05089.12 EER29331.1 - 0.0022 17.0 0.0 0.0029 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain DUF1524 PF07510.11 EER29332.1 - 1.9e-10 40.8 0.0 2.3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 EER29332.1 - 0.022 14.7 1.1 0.12 12.4 1.1 2.1 1 1 0 1 1 1 0 HNH endonuclease GH-E PF14410.6 EER29332.1 - 0.12 12.8 0.5 0.19 12.2 0.5 1.3 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Vps8 PF12816.7 EER29334.1 - 1.3e-63 214.1 0.4 3.3e-63 212.8 0.1 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EER29334.1 - 0.00016 21.5 1.2 0.84 9.5 0.0 3.8 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 EER29334.1 - 0.002 18.2 0.1 0.002 18.2 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger WD40 PF00400.32 EER29334.1 - 0.037 14.9 0.1 0.27 12.2 0.1 2.7 1 0 0 1 1 1 0 WD domain, G-beta repeat zf-RING_UBOX PF13445.6 EER29334.1 - 0.085 12.9 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Pkinase PF00069.25 EER29335.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EER29335.1 - 0.0003 20.8 0.1 0.0003 20.8 0.1 2.6 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EER29335.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EER29335.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_16 PF00722.21 EER29336.1 - 4.3e-09 36.1 0.2 4.9e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 APH PF01636.23 EER29338.1 - 3.1e-18 66.6 0.0 4e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER29338.1 - 0.0002 21.0 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3435 PF11917.8 EER29339.1 - 7.1e-103 344.7 6.6 1.7e-90 304.0 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) SRP1_TIP1 PF00660.17 EER29340.1 - 0.011 15.8 0.5 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Seripauperin and TIP1 family DUF2603 PF10788.9 EER29340.1 - 0.017 15.2 5.7 0.028 14.4 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2603) Triabin PF03973.13 EER29340.1 - 0.025 14.5 0.8 0.046 13.6 0.8 1.4 1 1 0 1 1 1 0 Triabin GlutR_dimer PF00745.20 EER29340.1 - 0.047 14.1 1.3 0.16 12.5 0.8 2.1 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF2603 PF10788.9 EER29341.1 - 0.011 15.8 6.0 0.059 13.4 0.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2603) SRP1_TIP1 PF00660.17 EER29341.1 - 0.033 14.2 0.4 8.1 6.6 0.0 2.8 2 0 0 2 2 2 0 Seripauperin and TIP1 family zf-CCHC PF00098.23 EER29341.1 - 0.052 13.6 1.7 0.093 12.9 1.7 1.4 1 0 0 1 1 1 0 Zinc knuckle GlutR_dimer PF00745.20 EER29341.1 - 0.088 13.3 0.4 0.98 9.9 0.4 2.4 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Glyco_transf_90 PF05686.12 EER29342.1 - 7.5e-13 48.1 0.8 7.8e-09 34.9 0.1 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 MASE4 PF17158.4 EER29342.1 - 0.035 13.4 0.2 0.087 12.1 0.2 1.6 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain GNAT_acetyltr_2 PF13718.6 EER29343.1 - 2.8e-97 324.6 0.0 6.1e-97 323.5 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EER29343.1 - 1.9e-92 309.2 0.0 2.9e-92 308.6 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EER29343.1 - 2.5e-65 219.6 0.0 7.3e-65 218.1 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EER29343.1 - 3.8e-34 116.5 0.0 9.9e-34 115.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EER29343.1 - 0.00057 19.7 0.1 0.036 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EER29343.1 - 0.049 13.9 0.0 0.91 9.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Acetyltransf_1 PF00583.25 EER29343.1 - 0.16 12.2 0.0 0.68 10.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Thioredoxin PF00085.20 EER29344.1 - 1.8e-27 95.3 0.0 1.1e-22 79.9 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EER29344.1 - 5.8e-06 25.9 0.0 7.8e-05 22.2 0.0 2.1 1 1 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EER29344.1 - 6.7e-05 23.3 0.3 0.011 16.2 0.3 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EER29344.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EER29344.1 - 0.058 13.7 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_7 PF13899.6 EER29344.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like ATP-synt PF00231.19 EER29345.1 - 1.7e-77 260.9 3.4 2.1e-77 260.6 3.4 1.0 1 0 0 1 1 1 1 ATP synthase PK_C PF02887.16 EER29345.1 - 0.092 13.0 0.6 0.25 11.6 0.6 1.7 1 1 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Topoisom_I_N PF02919.15 EER29346.1 - 5.7e-97 323.4 1.7 5.7e-97 323.4 1.7 3.5 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 EER29346.1 - 3e-96 321.2 5.1 3e-96 321.2 5.1 2.1 2 1 1 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 EER29346.1 - 7.9e-34 115.4 1.6 2.3e-33 113.9 1.0 2.2 2 0 0 2 2 2 1 C-terminal topoisomerase domain Csm1_N PF18504.1 EER29346.1 - 9.5 6.7 15.4 0.15 12.4 5.9 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain SQS_PSY PF00494.19 EER29347.1 - 6.1e-14 52.2 0.0 8.1e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Epimerase PF01370.21 EER29348.1 - 4.8e-18 65.5 0.0 6.2e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EER29348.1 - 5.6e-10 38.8 0.0 7.4e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EER29348.1 - 2e-09 36.9 0.0 1.1e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EER29348.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 EER29348.1 - 0.02 15.0 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EER29348.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding GPHH PF16905.5 EER29348.1 - 0.14 11.9 0.1 15 5.5 0.0 2.5 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated Vta1 PF04652.16 EER29349.1 - 1.6e-54 183.8 3.5 2.4e-54 183.3 2.6 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EER29349.1 - 5.8e-19 67.5 0.1 1.1e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 Vta1 C-terminal domain Peptidase_C2 PF00648.21 EER29350.1 - 9.4e-31 106.9 0.0 1.4e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EER29350.1 - 5.4e-09 36.4 0.0 1.7e-07 31.6 0.0 3.0 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.18 EER29350.1 - 0.00046 20.2 1.0 0.0009 19.3 1.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 EER29351.1 - 2.7e-57 190.7 0.4 6.6e-22 77.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EER29351.1 - 0.11 12.7 0.1 23 5.3 0.0 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase YtxH PF12732.7 EER29351.1 - 1.3 9.6 0.0 1.3 9.6 0.0 2.9 3 0 0 3 3 3 0 YtxH-like protein SNase PF00565.17 EER29352.1 - 1.8e-23 83.0 0.0 3.1e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.22 EER29353.1 - 9e-34 116.7 0.0 1.7e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EER29353.1 - 1.2e-15 57.2 0.0 1.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EER29353.1 - 1.3e-13 51.5 0.0 2.3e-12 47.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EER29353.1 - 0.00015 22.3 0.0 0.00034 21.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EER29353.1 - 0.0055 16.9 0.0 0.048 13.8 0.0 2.2 3 0 0 3 3 3 1 AAA domain MeaB PF03308.16 EER29353.1 - 0.096 11.6 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EER29353.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EER29353.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_primase_lrg PF04104.14 EER29354.1 - 1e-84 284.1 0.0 1.7e-84 283.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Ribosomal_L29 PF00831.23 EER29354.1 - 0.62 10.1 3.7 3.2 7.8 0.1 3.1 3 0 0 3 3 3 0 Ribosomal L29 protein Sec23_trunk PF04811.15 EER29355.1 - 2e-79 266.6 0.0 3e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EER29355.1 - 3e-30 104.8 0.0 5.8e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EER29355.1 - 1.1e-23 83.0 0.0 2.6e-23 81.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EER29355.1 - 2.6e-15 56.2 5.2 5e-15 55.2 5.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EER29355.1 - 8.1e-12 44.9 0.0 1.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EER29355.1 - 0.15 11.5 1.7 0.18 11.2 0.4 1.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 EER29356.1 - 2.4e-24 84.9 0.2 4.8e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EER29356.1 - 6.5e-15 55.4 0.1 1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.6 EER29357.1 - 8.3e-107 357.5 0.0 7.5e-56 189.5 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EER29357.1 - 2.1e-17 62.1 11.3 0.0003 20.5 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EER29357.1 - 3.3e-16 58.7 14.8 0.0019 17.8 0.1 6.6 3 2 3 6 6 6 4 TPR repeat TPR_2 PF07719.17 EER29357.1 - 1.7e-14 52.7 11.7 0.047 13.8 0.1 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 EER29357.1 - 1.1e-10 41.1 4.7 0.2 12.1 0.3 5.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EER29357.1 - 2.8e-10 40.2 3.6 0.044 14.6 0.0 5.9 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EER29357.1 - 8.3e-10 39.0 2.2 0.00075 20.0 0.8 3.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EER29357.1 - 5.3e-09 35.7 10.0 0.04 13.8 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EER29357.1 - 8.8e-09 35.9 8.5 0.0092 16.6 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EER29357.1 - 2.9e-08 33.3 1.7 0.014 15.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EER29357.1 - 6.3e-08 32.8 7.1 0.074 13.4 0.3 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER29357.1 - 3.4e-07 29.8 1.5 0.74 10.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 EER29357.1 - 0.00063 20.2 0.1 0.22 12.0 0.0 2.5 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 EER29357.1 - 0.003 17.7 3.3 0.62 10.2 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EER29357.1 - 0.0035 17.5 0.2 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EER29357.1 - 0.017 14.3 0.1 1.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EER29357.1 - 0.036 14.7 1.5 1.1e+02 3.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EER29358.1 - 3.2e-27 94.5 1.4 3.4e-15 55.9 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER29358.1 - 3.5e-19 68.8 2.6 3.2e-15 56.1 0.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.8 EER29358.1 - 0.011 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 EER29358.1 - 0.21 12.0 1.5 0.58 10.6 0.1 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain NCBP3 PF10309.9 EER29359.1 - 1.1e-22 79.7 0.0 1.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Nucleo_P87 PF07267.11 EER29359.1 - 2.6 6.8 5.1 4.2 6.1 5.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ribosomal_L29e PF01779.17 EER29360.1 - 8.6e-23 80.4 11.8 1.3e-22 79.8 11.8 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.16 EER29361.1 - 1.4e-15 57.0 0.0 1.9e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cytochrom_B561 PF03188.16 EER29362.1 - 5.6e-05 23.3 8.5 0.0001 22.4 8.5 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF3180 PF11377.8 EER29362.1 - 0.004 17.3 7.4 0.0041 17.3 2.1 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3180) PQ-loop PF04193.14 EER29363.1 - 4.1e-35 119.3 15.3 4.7e-18 64.7 0.3 2.9 3 0 0 3 3 3 2 PQ loop repeat SPATA9 PF15824.5 EER29363.1 - 0.23 10.7 0.2 2.1 7.6 0.0 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 9 zf-C2H2 PF00096.26 EER29364.1 - 3e-08 33.7 10.3 0.014 15.8 0.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER29364.1 - 1.1e-05 25.8 9.2 0.017 15.9 0.2 4.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EER29364.1 - 0.012 16.0 6.5 2 9.0 0.5 3.9 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 EER29364.1 - 0.032 14.5 4.4 0.17 12.2 0.1 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 EER29364.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain APH PF01636.23 EER29365.1 - 2.2e-42 145.7 0.0 7.9e-41 140.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EER29365.1 - 2.6e-05 23.7 0.0 7.7e-05 22.1 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EER29365.1 - 0.00025 20.7 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EER29365.1 - 0.00084 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 EER29365.1 - 0.0059 16.2 0.0 0.066 12.8 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.14 EER29365.1 - 0.025 13.8 0.0 0.72 9.0 0.0 2.3 1 1 0 1 1 1 0 Fructosamine kinase dUTPase PF00692.19 EER29366.1 - 1e-44 151.3 0.0 1.2e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 EER29366.1 - 0.022 13.6 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.12 EER29367.1 - 5.9e-12 45.5 0.0 1.7e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EER29367.1 - 1.5e-06 27.8 0.0 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase DoxD PF04173.13 EER29367.1 - 0.12 12.3 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 2 0 TQO small subunit DoxD Gluconate_2-dh3 PF13618.6 EER29367.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Formyl_trans_N PF00551.19 EER29368.1 - 1.7e-40 138.7 0.0 2e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase TFIIF_alpha PF05793.12 EER29369.1 - 7.1 5.1 5.0 9.8 4.6 5.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Afi1 PF07792.12 EER29370.1 - 1.8e-45 154.7 1.6 3.5e-45 153.7 1.6 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 EER29370.1 - 6.5e-38 129.2 0.0 1.1e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EER29370.1 - 1.6e-08 33.7 0.1 0.0037 16.0 0.0 4.0 3 1 1 4 4 4 3 Transport protein Avl9 PPP4R2 PF09184.11 EER29370.1 - 0.57 9.7 4.1 1 8.9 4.1 1.5 1 0 0 1 1 1 0 PPP4R2 EF-hand_6 PF13405.6 EER29371.1 - 2.1e-14 52.1 0.9 3.3e-06 26.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EER29371.1 - 1.2e-12 46.4 2.3 5.7e-06 25.5 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EER29371.1 - 4.5e-10 39.8 0.1 0.00011 22.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EER29371.1 - 1.5e-08 33.7 4.1 0.0012 18.2 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EER29371.1 - 6.7e-07 29.1 0.2 0.019 14.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EER29371.1 - 0.033 14.5 0.0 12 6.3 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain RabGAP-TBC PF00566.18 EER29372.1 - 1.5e-31 109.8 0.1 2.1e-26 92.9 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SET PF00856.28 EER29373.1 - 8e-08 32.8 0.0 3.6e-06 27.5 0.0 3.2 3 1 0 3 3 3 1 SET domain zf-MYND PF01753.18 EER29373.1 - 4.1 7.6 15.4 0.07 13.2 7.6 2.1 2 0 0 2 2 2 0 MYND finger WD40 PF00400.32 EER29374.1 - 3.3e-20 72.0 13.7 6.7e-06 26.7 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER29374.1 - 0.00019 21.6 0.0 0.0073 16.6 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 EER29374.1 - 8.9 4.4 36.2 15 3.6 36.2 1.2 1 0 0 1 1 1 0 Nop14-like family RRM_1 PF00076.22 EER29376.1 - 1.5e-14 53.6 0.0 2.1e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EER29376.1 - 0.021 14.9 0.3 0.037 14.1 0.3 1.5 1 1 0 1 1 1 0 Limkain b1 MA3 PF02847.17 EER29377.1 - 2.7e-28 98.2 0.1 8e-28 96.7 0.0 1.9 2 0 0 2 2 2 1 MA3 domain Abhydrolase_3 PF07859.13 EER29378.1 - 5.9e-32 111.2 0.0 9.5e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EER29378.1 - 0.0053 15.7 0.0 0.035 13.0 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.20 EER29378.1 - 0.032 14.3 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain ANAPC4_WD40 PF12894.7 EER29379.1 - 0.13 12.6 0.0 2.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HD PF01966.22 EER29380.1 - 7.7e-06 26.1 0.2 3.9e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 EER29380.1 - 0.14 11.8 0.1 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Thr_synth_N PF14821.6 EER29381.1 - 1.3e-25 89.4 0.0 2.9e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 EER29381.1 - 3.3e-23 82.6 0.0 2.4e-22 79.7 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ResIII PF04851.15 EER29383.1 - 2.5e-21 76.4 0.0 5.3e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EER29383.1 - 1.2e-18 67.4 0.1 4.5e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EER29383.1 - 8.6e-16 58.2 0.0 1.8e-15 57.1 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EER29383.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 EER29383.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase AAA_22 PF13401.6 EER29383.1 - 0.11 12.8 0.0 0.51 10.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain F_actin_cap_B PF01115.17 EER29384.1 - 1.5e-98 329.2 0.0 1.7e-97 325.8 0.0 1.9 2 0 0 2 2 2 1 F-actin capping protein, beta subunit Med11 PF10280.9 EER29385.1 - 4e-41 140.7 0.5 4.9e-41 140.4 0.5 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.32 EER29386.1 - 1.5e-48 161.7 21.3 5.6e-09 36.5 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EER29386.1 - 1.9e-38 131.7 0.0 2.8e-38 131.1 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EER29386.1 - 8.2e-13 48.5 0.0 0.015 15.6 0.0 5.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EER29386.1 - 6.2e-06 26.0 0.1 1.8e-05 24.5 0.1 1.8 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EER29386.1 - 0.0013 17.5 0.6 0.33 9.6 0.0 3.6 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EER29386.1 - 0.012 14.3 0.0 0.17 10.6 0.0 2.7 1 1 0 1 1 1 0 Nup133 N terminal like DUF4550 PF15084.6 EER29386.1 - 0.064 13.7 0.0 0.29 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) Ge1_WD40 PF16529.5 EER29386.1 - 0.093 11.7 1.0 23 3.8 0.3 3.4 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ELL PF10390.9 EER29386.1 - 0.21 11.1 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Abhydrolase_6 PF12697.7 EER29387.1 - 3e-20 73.8 0.1 4.9e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER29387.1 - 1.5e-07 31.4 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER29387.1 - 0.00016 21.0 0.3 0.00034 19.9 0.1 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 EER29387.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 EER29387.1 - 0.067 13.3 0.0 1 9.4 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Chlorophyllase2 PF12740.7 EER29387.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2417 PF10329.9 EER29388.1 - 2e-59 200.9 0.4 2.8e-59 200.4 0.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Wzy_C PF04932.15 EER29388.1 - 0.054 13.1 1.7 0.27 10.9 1.1 2.3 1 1 0 1 1 1 0 O-Antigen ligase AA_permease_2 PF13520.6 EER29389.1 - 3.6e-49 167.8 43.4 4.5e-49 167.4 43.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER29389.1 - 1.8e-27 96.1 37.4 2.5e-27 95.6 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease HrcA_DNA-bdg PF03444.15 EER29390.1 - 0.071 12.8 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Glyco_hydro_18 PF00704.28 EER29391.1 - 1.2e-69 235.5 0.9 1.8e-69 234.8 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EER29391.1 - 1e-13 51.5 14.2 1e-13 51.5 14.2 4.2 4 1 0 4 4 4 1 Chitin recognition protein LysM PF01476.20 EER29392.1 - 2.7e-26 91.3 1.7 3.9e-06 26.8 0.0 5.7 6 0 0 6 6 6 5 LysM domain CxC6 PF18721.1 EER29392.1 - 0.012 15.8 0.0 0.049 13.9 0.0 2.0 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases DUF1153 PF06627.11 EER29392.1 - 0.071 13.3 0.0 1.4 9.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) NPL4 PF05021.15 EER29393.1 - 4.8e-141 469.5 0.0 5.9e-141 469.2 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EER29393.1 - 2.6e-69 231.9 0.0 4.4e-69 231.2 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EER29393.1 - 0.059 13.9 0.0 0.36 11.3 0.0 2.2 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 CVNH PF08881.10 EER29394.1 - 1.2e-23 83.7 0.1 1.3e-23 83.5 0.1 1.0 1 0 0 1 1 1 1 CVNH domain FMN_red PF03358.15 EER29395.1 - 2e-08 34.1 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EER29395.1 - 3.4e-06 26.9 0.0 4.2e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EER29395.1 - 0.00056 20.1 0.0 0.0093 16.2 0.0 2.3 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EER29395.1 - 0.024 14.9 0.0 0.042 14.1 0.0 1.4 1 1 0 1 1 1 0 Flavodoxin domain adh_short PF00106.25 EER29396.1 - 3.3e-26 92.0 0.0 4.6e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER29396.1 - 5.2e-18 65.5 0.0 6.9e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER29396.1 - 2e-05 24.6 0.0 3.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EER29396.1 - 0.009 15.4 0.0 0.02 14.3 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) SLATT_2 PF18183.1 EER29396.1 - 0.028 14.2 0.2 4.5 7.0 0.0 2.4 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 2 PEX11 PF05648.14 EER29399.1 - 1.5e-26 93.3 0.0 2e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) zf-CCCH PF00642.24 EER29400.1 - 1.9e-16 59.5 28.3 8.2e-06 25.6 0.5 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EER29400.1 - 2.4e-14 52.8 27.8 7.8e-05 22.6 2.7 5.2 5 0 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EER29400.1 - 3.5e-09 37.3 28.1 0.00022 21.9 1.1 5.4 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 EER29400.1 - 4.8e-06 26.2 0.8 4.8e-06 26.2 0.8 5.1 5 0 0 5 5 5 2 CCCH-type zinc finger TRP_N PF14558.6 EER29400.1 - 0.3 11.5 3.5 7.2 7.0 0.3 2.5 2 1 0 2 2 2 0 ML-like domain zf-C3H1 PF10650.9 EER29400.1 - 1.3 8.9 0.1 1.3 8.9 0.1 3.6 4 0 0 4 4 4 0 Putative zinc-finger domain zf-CCCH_3 PF15663.5 EER29400.1 - 3.7 7.8 13.0 32 4.8 3.0 3.5 2 1 2 4 4 4 0 Zinc-finger containing family Glyco_hydro_18 PF00704.28 EER29401.1 - 1.1e-57 196.1 0.0 1.4e-57 195.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3712 PF12505.8 EER29402.1 - 7.9e-35 119.9 0.9 2.5e-34 118.3 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.13 EER29402.1 - 0.021 15.4 0.2 0.15 12.6 0.1 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant protein Sel1 PF08238.12 EER29403.1 - 1.1e-14 54.5 8.9 0.0016 19.0 3.0 4.4 4 0 0 4 4 4 3 Sel1 repeat Nucleo_P87 PF07267.11 EER29403.1 - 3.4 6.4 8.1 6 5.6 8.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1776 PF08643.10 EER29405.1 - 2.6e-97 325.8 0.0 3.2e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.10 EER29406.1 - 4.3e-68 229.2 1.1 5.1e-68 228.9 0.2 1.6 2 0 0 2 2 2 1 WLM domain zf-RanBP PF00641.18 EER29406.1 - 0.00025 20.3 1.9 0.00025 20.3 1.9 2.6 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF45 PF01863.17 EER29406.1 - 0.0017 18.4 2.7 0.0034 17.5 2.7 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.9 EER29406.1 - 0.022 14.6 0.2 0.041 13.7 0.2 1.4 1 0 0 1 1 1 0 SprT-like family DZR PF12773.7 EER29406.1 - 0.028 14.4 8.2 0.11 12.6 8.2 2.0 1 1 0 1 1 1 0 Double zinc ribbon SVIP PF15811.5 EER29406.1 - 0.082 13.4 5.8 3.3 8.2 0.4 3.0 2 0 0 2 2 2 0 Small VCP/p97-interacting protein WD40 PF00400.32 EER29407.1 - 5.4e-50 166.3 31.1 1.3e-06 29.0 0.4 11.9 13 1 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.12 EER29407.1 - 2.2e-21 76.2 0.0 5.5e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EER29407.1 - 3.5e-21 75.3 7.0 0.045 14.1 0.0 10.7 4 3 4 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EER29407.1 - 1.6e-07 30.6 6.7 0.15 11.0 0.2 5.8 2 2 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EER29407.1 - 6.5e-06 25.1 0.8 0.29 9.7 0.0 4.8 6 1 0 6 6 6 2 Nucleoporin Nup120/160 Frtz PF11768.8 EER29407.1 - 0.00018 20.0 0.1 0.039 12.3 0.0 3.2 3 1 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EER29407.1 - 0.0018 17.7 0.1 3.1 7.1 0.0 3.9 3 2 0 4 4 4 1 WD40-like domain RAB3GAP2_N PF14655.6 EER29407.1 - 0.0019 17.5 0.3 0.48 9.6 0.0 3.4 4 0 0 4 4 4 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Nucleoporin_N PF08801.11 EER29407.1 - 0.0085 14.9 7.4 0.82 8.3 0.2 5.0 4 2 2 6 6 6 1 Nup133 N terminal like CDtoxinA PF03498.14 EER29407.1 - 0.15 11.7 0.1 26 4.4 0.0 2.7 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain P34-Arc PF04045.14 EER29408.1 - 1.2e-104 349.3 0.2 1.4e-104 349.0 0.2 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 EER29408.1 - 0.022 14.4 0.4 0.066 12.8 0.1 2.0 2 0 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) SpoIIE PF07228.12 EER29410.1 - 1.3e-05 25.2 0.0 7.1e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EER29410.1 - 5.3e-05 23.0 0.0 0.05 13.2 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C Fcf1 PF04900.12 EER29411.1 - 2.3e-18 66.4 0.7 2.4e-16 59.9 0.7 3.2 1 1 0 1 1 1 1 Fcf1 Cmc1 PF08583.10 EER29412.1 - 2.2e-18 66.0 4.0 2.5e-18 65.8 4.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like WD40 PF00400.32 EER29413.1 - 1.1e-16 60.8 10.1 0.0039 18.0 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER29413.1 - 2.8e-06 27.5 0.6 0.049 13.9 0.1 4.4 3 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER29413.1 - 0.00015 20.6 2.1 0.005 15.5 0.2 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 RRN3 PF05327.11 EER29415.1 - 3.9e-180 600.1 0.0 3.9e-180 600.1 0.0 1.3 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 IBN_N PF03810.19 EER29415.1 - 0.028 14.3 0.0 0.072 13.0 0.0 1.7 1 0 0 1 1 1 0 Importin-beta N-terminal domain RecO_C PF02565.15 EER29415.1 - 0.12 12.2 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Recombination protein O C terminal Urb2 PF10441.9 EER29415.1 - 0.17 11.8 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Urb2/Npa2 family Abhydrolase_3 PF07859.13 EER29416.1 - 1.2e-44 152.7 0.0 1.2e-43 149.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EER29416.1 - 9.3e-12 44.6 0.1 2.9e-11 42.9 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EER29416.1 - 0.0042 16.6 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EER29416.1 - 0.043 12.7 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase Chlorophyllase2 PF12740.7 EER29416.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Hemerythrin PF01814.23 EER29417.1 - 3.9e-12 46.9 1.5 5.4e-12 46.5 1.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CDC37_N PF03234.14 EER29417.1 - 0.018 15.9 0.3 0.035 15.0 0.1 1.6 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding TCTP PF00838.17 EER29417.1 - 0.088 13.1 0.2 0.11 12.8 0.2 1.2 1 0 0 1 1 1 0 Translationally controlled tumour protein TPR_22 PF18833.1 EER29417.1 - 0.12 12.5 0.7 0.12 12.5 0.7 2.4 2 2 2 4 4 4 0 Tetratricopeptide repeat tRNA-synt_2 PF00152.20 EER29418.1 - 3e-72 243.4 0.2 4.7e-72 242.7 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EER29418.1 - 1.9e-17 63.3 0.0 2.9e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EER29418.1 - 0.00032 20.6 1.2 0.001 19.0 0.8 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EER29418.1 - 0.00052 19.6 0.8 0.69 9.4 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) LtuA PF17446.2 EER29418.1 - 0.13 12.7 0.2 1.7 9.1 0.0 2.7 3 0 0 3 3 3 0 Late transcription unit A HSP90 PF00183.18 EER29419.1 - 1.3e-222 740.3 34.0 1.6e-222 740.0 34.0 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EER29419.1 - 6.4e-15 55.6 0.1 1.2e-14 54.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EER29419.1 - 2.2e-10 40.5 0.1 2.2e-10 40.5 0.1 2.3 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase M16C_assoc PF08367.11 EER29419.1 - 0.12 11.5 9.9 4.7 6.3 0.0 2.8 2 0 0 2 2 2 0 Peptidase M16C associated LOH1CR12 PF10158.9 EER29419.1 - 0.6 10.1 3.7 0.41 10.7 0.2 2.5 3 0 0 3 3 3 0 Tumour suppressor protein Septin PF00735.18 EER29420.1 - 3.3e-10 39.7 0.0 1.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 Septin AAA_33 PF13671.6 EER29420.1 - 0.011 15.9 0.0 0.03 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EER29420.1 - 0.012 14.7 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EER29420.1 - 0.013 14.8 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EER29420.1 - 0.017 15.6 0.8 0.059 13.9 0.1 2.2 2 1 0 2 2 2 0 ABC transporter NACHT PF05729.12 EER29420.1 - 0.03 14.3 0.1 0.075 12.9 0.1 1.7 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EER29420.1 - 0.044 13.9 0.0 0.083 13.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Roc PF08477.13 EER29420.1 - 0.06 13.6 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EER29420.1 - 0.064 12.8 0.1 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 EER29420.1 - 0.094 12.3 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EER29420.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HLH PF00010.26 EER29421.1 - 2.1e-13 50.0 0.3 3.9e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NTF2 PF02136.20 EER29422.1 - 8.2e-24 84.5 0.3 1.3e-23 83.8 0.3 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EER29422.1 - 2.5e-07 30.4 0.1 4.9e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EER29422.1 - 0.38 10.8 1.8 0.45 10.6 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif Merozoite_SPAM PF07133.11 EER29422.1 - 2.4 8.1 8.3 4.3 7.3 8.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PknG_rubred PF16919.5 EER29423.1 - 0.28 11.3 2.2 2.6 8.2 0.3 2.0 1 1 1 2 2 2 0 Protein kinase G rubredoxin domain TPR_17 PF13431.6 EER29424.1 - 1.8e-05 24.8 0.0 0.45 11.0 0.1 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EER29424.1 - 0.016 16.0 0.4 40 5.4 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EER29424.1 - 0.025 14.6 0.1 0.69 10.2 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EER29424.1 - 0.035 13.8 8.6 0.17 11.6 0.0 4.3 4 0 0 4 4 4 0 TPR repeat MAD PF05557.13 EER29424.1 - 0.038 12.4 0.4 0.05 12.0 0.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TPR_1 PF00515.28 EER29424.1 - 0.051 13.4 1.3 1.3 9.0 0.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EER29424.1 - 0.32 11.3 2.8 1.6 9.1 0.6 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EER29424.1 - 8.7 6.5 6.9 2 8.6 0.3 3.2 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 EER29425.1 - 1.4e-75 254.1 0.0 1.7e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29425.1 - 4.5e-39 134.3 0.0 6.2e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EER29425.1 - 0.00027 20.0 0.0 0.018 14.0 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EER29425.1 - 0.0059 16.5 0.0 0.0059 16.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EER29425.1 - 0.014 14.8 0.3 0.04 13.3 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EER29425.1 - 0.014 14.7 1.0 0.053 12.8 0.1 2.3 2 1 1 3 3 3 0 Kinase-like SIR2 PF02146.17 EER29426.1 - 4e-32 111.6 0.0 6.6e-32 110.9 0.0 1.3 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.21 EER29427.1 - 3e-56 190.3 7.2 4e-56 189.9 7.2 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EER29427.1 - 1.2e-05 25.3 1.0 8.5e-05 22.6 0.1 2.5 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF111 PF01969.17 EER29427.1 - 0.044 12.9 0.0 0.081 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF111 FGGY_C PF02782.16 EER29428.1 - 3.7e-30 105.2 0.0 1.7e-29 103.0 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EER29428.1 - 7.6e-19 68.2 0.0 4.4e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.12 EER29429.1 - 6.2e-39 133.4 0.3 6.2e-39 133.4 0.3 3.1 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 EER29429.1 - 0.0054 16.9 0.2 1.7 9.1 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat STAG PF08514.11 EER29429.1 - 0.21 11.5 0.8 0.67 9.9 0.0 2.3 2 0 0 2 2 2 0 STAG domain DUF4844 PF16133.5 EER29429.1 - 0.23 12.0 1.0 16 6.1 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) Esterase PF00756.20 EER29430.1 - 2.5e-55 187.9 0.0 3.1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EER29430.1 - 4.1e-06 26.4 0.0 0.0001 21.9 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EER29430.1 - 0.0015 18.0 0.2 0.003 17.1 0.2 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EER29430.1 - 0.0045 16.3 0.0 0.0072 15.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EER29430.1 - 0.0064 15.4 0.0 0.016 14.1 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 EER29430.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.16 EER29430.1 - 0.049 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EER29430.1 - 0.11 12.2 0.1 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EER29430.1 - 0.11 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_C50 PF03568.17 EER29431.1 - 6e-156 519.5 0.0 9.6e-156 518.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 CHAT PF12770.7 EER29431.1 - 1.1e-05 25.0 0.3 0.0013 18.3 0.0 3.2 3 0 0 3 3 3 1 CHAT domain TPR_14 PF13428.6 EER29431.1 - 0.14 13.0 5.3 10 7.3 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EER29431.1 - 0.3 11.3 11.4 46 4.5 0.1 6.7 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 EER29431.1 - 1.2 9.8 3.9 5.6 7.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5321 PF17254.2 EER29432.1 - 9.2e-41 138.9 1.7 1.1e-40 138.6 1.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) COG4 PF08318.12 EER29432.1 - 0.014 14.5 0.3 0.017 14.2 0.3 1.0 1 0 0 1 1 1 0 COG4 transport protein DUF3775 PF12616.8 EER29432.1 - 0.11 12.6 0.6 0.17 11.9 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3775) Qua1 PF16274.5 EER29432.1 - 0.12 12.3 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Qua1 domain DUF3176 PF11374.8 EER29434.1 - 1.5e-05 25.1 4.9 0.00018 21.7 0.4 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3176) Mito_carr PF00153.27 EER29435.1 - 3.1e-73 241.8 0.4 5e-25 87.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EER29435.1 - 3.5e-15 56.2 0.8 2.1e-08 34.5 0.3 3.8 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EER29435.1 - 2.6e-14 51.8 0.3 5.5e-07 29.0 0.1 5.0 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 EER29435.1 - 2e-12 45.7 2.3 9.8e-07 27.9 0.1 5.3 6 0 0 6 6 6 2 EF hand EF-hand_5 PF13202.6 EER29435.1 - 1.7e-06 27.3 2.2 5.8e-05 22.4 0.1 3.6 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 EER29435.1 - 0.00012 21.9 3.9 3.5 7.6 0.1 5.5 5 2 1 6 6 6 3 EF-hand domain pair EF-hand_9 PF14658.6 EER29435.1 - 0.0047 17.2 0.0 8.6 6.8 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain Peptidase_M22 PF00814.25 EER29437.1 - 7.2e-51 173.5 0.0 5.9e-48 163.9 0.0 3.3 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.6 EER29437.1 - 0.0033 17.2 0.1 0.007 16.2 0.1 1.5 1 0 0 1 1 1 1 YycC-like protein Myb_DNA-bind_6 PF13921.6 EER29439.1 - 2.5e-10 40.5 0.8 5.6e-09 36.1 0.3 2.3 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EER29439.1 - 3.2e-07 30.4 0.4 2.5e-06 27.6 0.0 2.4 2 1 0 2 2 2 1 Myb-like DNA-binding domain Rap1_C PF11626.8 EER29439.1 - 0.032 14.3 0.0 0.068 13.3 0.0 1.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EPL1 PF10513.9 EER29441.1 - 1.8e-32 112.9 0.1 4.6e-32 111.6 0.0 1.8 2 0 0 2 2 2 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 EER29441.1 - 8.4e-32 109.6 3.2 8.4e-32 109.6 3.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EER29441.1 - 3.2e-27 94.6 0.7 3.2e-27 94.6 0.7 2.7 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EER29441.1 - 7.9e-14 50.9 3.4 7.9e-14 50.9 3.4 2.4 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EER29441.1 - 9e-09 35.1 10.0 9e-09 35.1 10.0 2.6 2 0 0 2 2 2 1 PHD-finger RskA PF10099.9 EER29441.1 - 0.0023 18.2 0.7 0.0023 18.2 0.7 2.4 3 0 0 3 3 3 1 Anti-sigma-K factor rskA Bromodomain PF00439.25 EER29441.1 - 0.1 12.7 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Bromodomain zf-PHD-like PF15446.6 EER29441.1 - 3.7 7.2 13.0 0.016 14.8 2.2 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 EER29441.1 - 9.2 6.7 18.4 15 6.0 3.8 2.7 2 0 0 2 2 2 0 C1 domain RRM_1 PF00076.22 EER29442.1 - 1.3e-20 72.9 0.0 2.1e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER29442.1 - 4.8e-05 23.0 0.0 6.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy-30 PF05186.13 EER29443.1 - 9.9e-13 47.6 0.8 1.6e-12 46.9 0.8 1.3 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.11 EER29444.1 - 4.5e-26 91.0 0.0 1.3e-25 89.5 0.0 1.8 1 0 0 1 1 1 1 VRR-NUC domain Pox_A_type_inc PF04508.12 EER29444.1 - 0.077 12.9 1.4 0.27 11.1 0.6 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Ribosomal_S13_N PF08069.12 EER29445.1 - 2.6e-30 104.2 0.1 4.4e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EER29445.1 - 1.4e-15 57.3 0.2 1.9e-15 56.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EER29445.1 - 0.033 14.1 0.1 0.08 12.9 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain HOIP-UBA PF16678.5 EER29445.1 - 0.084 12.9 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 HOIP UBA domain pair Chromate_transp PF02417.15 EER29446.1 - 6.1e-61 205.1 26.5 4.9e-34 117.7 12.2 2.1 2 0 0 2 2 2 2 Chromate transporter CcmH PF03918.14 EER29446.1 - 0.19 11.0 0.3 0.97 8.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Egh16-like PF11327.8 EER29447.1 - 6e-62 209.3 2.5 2.4e-61 207.3 2.5 1.8 1 1 0 1 1 1 1 Egh16-like virulence factor ketoacyl-synt PF00109.26 EER29448.1 - 1.2e-76 257.7 0.1 1.6e-75 254.0 0.1 2.8 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EER29448.1 - 9.4e-32 109.5 0.1 3.3e-31 107.7 0.0 2.0 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_51 PF18558.1 EER29448.1 - 1.7e-28 98.3 0.0 6.1e-28 96.5 0.0 2.1 2 0 0 2 2 1 1 Helix-turn-helix domain PP-binding PF00550.25 EER29448.1 - 5.1e-23 81.2 5.3 4e-12 46.3 0.3 2.9 3 0 0 3 3 2 2 Phosphopantetheine attachment site Acyl_transf_1 PF00698.21 EER29448.1 - 1.2e-21 77.5 0.0 2.5e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EER29448.1 - 3.4e-16 59.3 0.0 6.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EER29448.1 - 6.4e-15 55.7 0.0 1.5e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.13 EER29448.1 - 5.4e-14 52.6 0.0 8.6e-11 42.1 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_25 PF13649.6 EER29448.1 - 3.3e-13 50.2 0.0 9.4e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER29448.1 - 3.1e-12 46.6 0.0 7.4e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER29448.1 - 1.6e-09 37.8 0.0 8.4e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER29448.1 - 1.8e-09 38.1 0.0 4.9e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.21 EER29448.1 - 3.9e-09 36.3 0.0 5e-05 22.9 0.0 3.0 3 0 0 3 3 3 2 Prolyl oligopeptidase family KAsynt_C_assoc PF16197.5 EER29448.1 - 1.6e-07 31.7 0.0 5.3e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 EER29448.1 - 3.9e-07 30.9 0.6 6e-06 27.0 0.1 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.18 EER29448.1 - 4.3e-05 23.0 0.0 9.6e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DLH PF01738.18 EER29448.1 - 0.00075 19.1 0.0 0.095 12.2 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Thiolase_N PF00108.23 EER29448.1 - 0.00092 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 EER29448.1 - 0.0019 17.9 0.5 0.23 11.2 0.0 2.9 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Abhydrolase_2 PF02230.16 EER29448.1 - 0.0047 16.8 0.0 3.5 7.4 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase COesterase PF00135.28 EER29448.1 - 0.012 14.5 0.0 0.026 13.4 0.0 1.5 1 0 0 1 1 1 0 Carboxylesterase family Methyltransf_16 PF10294.9 EER29448.1 - 0.14 11.9 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase AXE1 PF05448.12 EER29448.1 - 0.19 10.3 0.0 0.34 9.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) AMP-binding PF00501.28 EER29449.1 - 1.7e-28 99.4 0.0 4.8e-28 97.9 0.0 1.6 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EER29449.1 - 1.5e-26 93.1 0.0 2.2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EER29449.1 - 1.3e-06 28.1 0.0 4.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EER29449.1 - 1.8e-05 25.0 0.1 8.1e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 EER29449.1 - 0.17 11.8 0.0 0.69 9.8 0.0 2.0 1 0 0 1 1 1 0 KR domain Myb_DNA-binding PF00249.31 EER29450.1 - 5e-32 109.9 8.5 7e-10 38.9 0.0 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER29450.1 - 2.4e-25 88.6 0.2 9.6e-10 38.6 0.0 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EER29450.1 - 2.6e-05 24.2 0.2 0.027 14.6 0.0 3.3 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EER29450.1 - 0.00022 21.2 0.0 0.091 12.8 0.0 3.1 1 1 2 3 3 3 1 SLIDE Myb_DNA-bind_7 PF15963.5 EER29450.1 - 0.00035 20.4 0.5 0.022 14.7 0.2 2.8 1 1 2 3 3 3 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EER29450.1 - 0.025 14.7 0.0 1.4 9.1 0.0 2.5 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 MADF_DNA_bdg PF10545.9 EER29450.1 - 0.058 13.7 1.6 0.19 12.1 0.2 2.2 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like adh_short PF00106.25 EER29451.1 - 3.8e-40 137.5 0.0 5e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER29451.1 - 3.2e-32 112.0 0.0 5.5e-32 111.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER29451.1 - 4.4e-07 30.0 0.1 6.1e-07 29.5 0.1 1.1 1 0 0 1 1 1 1 KR domain FAD_binding_4 PF01565.23 EER29452.1 - 9.8e-21 74.0 0.7 9.8e-21 74.0 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EER29452.1 - 0.029 14.5 0.0 0.081 13.0 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Methyltransf_2 PF00891.18 EER29453.1 - 2.6e-23 82.5 0.0 4.4e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Phage_rep_org_N PF09681.10 EER29453.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Aldo_ket_red PF00248.21 EER29454.1 - 1e-54 185.7 0.0 1.3e-54 185.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_2 PF00891.18 EER29455.1 - 2.1e-19 69.7 0.0 7.4e-19 67.9 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EER29455.1 - 0.0098 15.8 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain DUF1857 PF08982.11 EER29456.1 - 1.9e-43 147.8 0.2 2.9e-41 140.7 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1857) SpoU_methylas_C PF12105.8 EER29456.1 - 0.081 12.6 0.4 0.34 10.6 0.1 2.2 3 0 0 3 3 3 0 SpoU, rRNA methylase, C-terminal p450 PF00067.22 EER29457.1 - 8.7e-69 232.4 0.0 1.1e-68 232.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tim17 PF02466.19 EER29457.1 - 0.12 12.8 0.0 1.7 9.1 0.0 2.2 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family FA_hydroxylase PF04116.13 EER29459.1 - 3.8e-23 82.3 13.1 6e-23 81.7 13.1 1.3 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Pep_deformylase PF01327.21 EER29459.1 - 0.13 11.9 0.3 0.21 11.2 0.3 1.3 1 0 0 1 1 1 0 Polypeptide deformylase 7tm_2 PF00002.24 EER29460.1 - 1.7e-08 34.0 5.4 1.7e-08 34.0 5.4 2.2 1 1 0 2 2 2 2 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EER29460.1 - 0.004 16.3 5.5 0.0075 15.4 4.6 1.9 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor RRM_1 PF00076.22 EER29461.1 - 1.1e-29 102.1 0.3 9.9e-14 50.9 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER29461.1 - 2.9e-05 23.8 0.0 0.75 9.7 0.0 3.4 3 0 0 3 3 3 2 Occluded RNA-recognition motif OGG_N PF07934.12 EER29462.1 - 8.4e-39 132.4 0.1 1.5e-38 131.5 0.1 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EER29462.1 - 3.4e-14 53.2 0.0 6e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EER29462.1 - 0.0063 16.3 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF2256 PF10013.9 EER29462.1 - 0.04 14.0 0.8 0.12 12.5 0.8 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) SET PF00856.28 EER29463.1 - 5.6e-13 49.6 0.0 1.4e-12 48.3 0.0 1.7 1 1 0 1 1 1 1 SET domain DUF2688 PF10892.8 EER29463.1 - 0.11 12.0 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) Pkinase PF00069.25 EER29464.1 - 1.5e-15 57.3 0.0 4.3e-15 55.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29464.1 - 0.00024 20.5 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER29465.1 - 3.3e-10 40.3 0.0 2.2e-09 37.6 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family BTRD1 PF17660.1 EER29467.1 - 4.4e-109 356.2 22.5 4.7e-23 80.8 0.3 5.0 5 0 0 5 5 5 5 Bacterial tandem repeat domain 1 UvrA_inter PF17760.1 EER29467.1 - 1e-08 35.2 0.6 0.92 9.6 0.0 5.0 5 0 0 5 5 5 4 UvrA interaction domain IreB PF06135.12 EER29467.1 - 1.5e-05 25.1 2.3 0.97 9.7 0.1 4.1 2 2 2 4 4 4 2 IreB regulatory phosphoprotein Glyoxalase_4 PF13669.6 EER29467.1 - 0.0038 17.5 0.1 18 5.7 0.0 4.4 4 1 1 5 5 5 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily UPF0180 PF03698.13 EER29467.1 - 0.014 15.5 0.5 1.1 9.5 0.0 3.5 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0180) DUF3018 PF11455.8 EER29467.1 - 0.043 13.8 0.0 2.4 8.1 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3018) LNS2 PF08235.13 EER29467.1 - 0.057 12.9 0.2 0.24 10.9 0.0 2.0 3 0 0 3 3 3 0 LNS2 (Lipin/Ned1/Smp2) MciZ PF13072.6 EER29467.1 - 0.11 12.4 0.5 79 3.2 0.1 3.4 3 0 0 3 3 3 0 Mother cell inhibitor of FtsZ DEAD PF00270.29 EER29468.1 - 3e-16 59.7 0.0 5.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EER29468.1 - 2.2e-10 40.8 0.0 6.6e-10 39.2 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EER29468.1 - 6.3e-07 29.7 0.0 1.5e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 EER29468.1 - 0.21 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Acetyltransf_1 PF00583.25 EER29469.1 - 2.9e-15 56.5 0.0 3.5e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EER29469.1 - 2.2e-10 40.3 0.0 4.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EER29469.1 - 3.4e-10 40.2 0.1 5.2e-10 39.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER29469.1 - 2.9e-07 30.5 0.0 3.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EER29469.1 - 8.7e-06 26.4 0.0 1.1e-05 26.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER29469.1 - 0.00026 21.0 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EER29469.1 - 0.0018 18.3 0.0 0.02 15.0 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EER29469.1 - 0.0033 16.9 0.0 0.0042 16.6 0.0 1.1 1 0 0 1 1 1 1 Putative acetyl-transferase PanZ PF12568.8 EER29469.1 - 0.0046 16.7 0.1 0.0075 16.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ GNAT_acetyltran PF12746.7 EER29469.1 - 0.0074 15.9 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase TPR_15 PF13429.6 EER29469.1 - 0.02 14.1 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.20 EER29470.1 - 5.9e-38 130.2 0.0 5.9e-38 130.2 0.0 2.6 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EER29470.1 - 5.3e-16 59.5 0.0 2.4e-15 57.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EER29470.1 - 4.2e-14 52.7 5.3 4.2e-14 52.7 5.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EER29470.1 - 1e-13 50.7 1.1 2.1e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EER29470.1 - 1.6e-06 28.1 0.0 3.4e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Fungal_trans_2 PF11951.8 EER29471.1 - 6.2e-11 41.7 0.0 1.3e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAS_I_H PF18314.1 EER29471.1 - 0.0019 17.8 0.2 0.9 9.1 0.1 2.6 2 0 0 2 2 2 2 Fatty acid synthase type I helical domain Rax2 PF12768.7 EER29472.1 - 1.6e-65 220.6 0.0 8.7e-65 218.2 0.0 2.3 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DUF5122 PF17164.4 EER29472.1 - 0.0048 17.1 17.7 7.5 6.9 0.1 7.9 7 0 0 7 7 7 3 Domain of unknown function (DUF5122) beta-propeller Gp5_C PF06715.12 EER29472.1 - 1.1 9.6 4.4 13 6.2 0.1 4.4 4 0 0 4 4 4 0 Gp5 C-terminal repeat (3 copies) POB3_N PF17292.2 EER29473.1 - 3.5e-31 107.5 0.0 1.3e-29 102.5 0.0 2.6 2 0 0 2 2 2 1 POB3-like N-terminal PH domain SSrecog PF03531.14 EER29473.1 - 1.7e-29 101.5 0.1 9.1e-29 99.2 0.0 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EER29473.1 - 3.5e-24 85.0 0.0 2.9e-23 82.1 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 EER29473.1 - 0.14 12.5 0.0 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain SAP PF02037.27 EER29474.1 - 1.7e-11 43.6 0.0 3.6e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EER29474.1 - 6.9e-08 32.2 0.5 2.1e-07 30.6 0.5 1.8 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain Methyltransf_11 PF08241.12 EER29475.1 - 0.13 12.9 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF3455 PF11937.8 EER29476.1 - 5.1e-39 134.2 0.0 6.2e-39 133.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.10 EER29477.1 - 1.3e-32 112.7 18.6 7.7e-32 110.3 10.9 3.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EER29477.1 - 4.7e-13 49.3 2.7 0.012 16.1 0.0 7.6 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 EER29477.1 - 6.3e-11 42.5 8.0 0.21 12.0 0.1 7.9 4 2 4 9 9 9 3 HEAT repeats HEAT PF02985.22 EER29477.1 - 3.2e-09 36.2 8.2 0.79 10.2 0.1 8.9 9 0 0 9 9 9 1 HEAT repeat Cnd1 PF12717.7 EER29477.1 - 4.4e-06 26.8 0.7 14 5.7 0.0 6.4 5 2 2 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EER29477.1 - 3.4e-05 24.4 0.2 2 9.0 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 EER29477.1 - 0.00012 21.8 0.2 1.2 8.8 0.0 4.2 5 1 0 5 5 5 2 NUC173 domain Adaptin_N PF01602.20 EER29477.1 - 0.00041 19.0 0.1 0.21 10.1 0.0 3.0 3 1 0 3 3 3 2 Adaptin N terminal region UNC45-central PF11701.8 EER29477.1 - 0.00042 20.3 0.0 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central DUF3385 PF11865.8 EER29477.1 - 0.00098 19.1 1.2 0.079 12.9 0.0 4.3 6 1 0 6 6 6 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EER29477.1 - 0.01 15.4 0.2 0.94 9.0 0.0 3.5 4 0 0 4 4 4 0 CLASP N terminal TAF6_C PF07571.13 EER29477.1 - 0.018 15.4 0.0 1.1 9.7 0.0 3.4 3 1 0 3 3 2 0 TAF6 C-terminal HEAT repeat domain DRIM PF07539.12 EER29477.1 - 0.05 11.9 0.2 9.6 4.4 0.0 3.7 2 1 2 4 4 4 0 Down-regulated in metastasis Ecm29 PF13001.7 EER29477.1 - 0.16 10.6 0.0 1.3 7.6 0.0 2.3 2 1 1 3 3 3 0 Proteasome stabiliser CRM1_C PF08767.11 EER29477.1 - 0.22 10.7 0.1 0.82 8.8 0.1 2.0 1 0 0 1 1 1 0 CRM1 C terminal MFS_1 PF07690.16 EER29478.1 - 6.3e-37 127.3 34.1 6.3e-37 127.3 34.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Zip PF02535.22 EER29478.1 - 2.1 7.5 10.5 1.1 8.4 0.8 2.6 3 0 0 3 3 3 0 ZIP Zinc transporter Fungal_trans PF04082.18 EER29479.1 - 6.7e-25 87.6 0.9 1.1e-24 87.0 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29479.1 - 6.6e-09 35.8 11.8 1.2e-08 34.9 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DDE_Tnp_1_3 PF13612.6 EER29479.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Transposase DDE domain adh_short_C2 PF13561.6 EER29480.1 - 7e-59 199.2 0.0 8.5e-59 198.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER29480.1 - 9.1e-47 159.0 0.3 1.2e-46 158.7 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER29480.1 - 2.2e-10 40.7 0.1 3.3e-10 40.2 0.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EER29480.1 - 0.059 13.2 1.3 0.26 11.1 1.0 1.9 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EER29481.1 - 9.2e-44 150.2 0.9 3.5e-43 148.3 0.9 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EER29481.1 - 2.8e-09 37.0 2.3 2.8e-09 37.0 2.3 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EER29481.1 - 1.3e-08 34.6 5.1 1.7e-08 34.3 2.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EER29481.1 - 4.8e-06 25.5 3.4 0.024 13.3 0.2 3.3 3 0 0 3 3 3 3 HI0933-like protein Pyr_redox_2 PF07992.14 EER29481.1 - 0.00042 19.7 2.6 0.026 13.8 2.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EER29481.1 - 0.00081 18.7 0.1 0.071 12.3 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EER29481.1 - 0.0064 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EER29481.1 - 0.026 13.8 0.1 0.066 12.4 0.1 1.6 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 EER29481.1 - 0.057 12.5 0.3 0.057 12.5 0.3 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A GMC_oxred_N PF00732.19 EER29481.1 - 0.071 12.5 0.1 0.94 8.8 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 EER29481.1 - 0.091 12.0 0.1 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 EER29482.1 - 1.2e-148 495.5 0.0 1.4e-148 495.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TGS PF02824.21 EER29482.1 - 0.011 15.8 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 TGS domain Lactamase_B PF00753.27 EER29483.1 - 4.5e-07 30.1 2.2 7.7e-07 29.3 2.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EER29483.1 - 0.00049 19.7 0.0 0.001 18.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Ribosomal_L7Ae PF01248.26 EER29484.1 - 9.2e-23 79.8 0.0 1.2e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2 PF00096.26 EER29485.1 - 6.9e-10 38.8 11.4 2.4e-05 24.5 4.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER29485.1 - 7.4e-09 35.7 15.6 3.3e-05 24.1 0.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER29485.1 - 7.6e-07 29.5 10.9 0.0014 19.3 3.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EER29485.1 - 4.8e-06 26.8 1.3 2e-05 24.8 1.3 2.1 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EER29485.1 - 0.00013 21.9 2.4 0.00013 21.9 2.4 2.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER29485.1 - 0.00081 19.6 1.8 0.00081 19.6 1.8 3.1 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding Med3 PF11593.8 EER29485.1 - 0.0046 16.2 1.2 0.0077 15.5 1.2 1.4 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal SUIM_assoc PF16619.5 EER29485.1 - 0.23 11.6 6.6 0.7 10.0 6.6 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-C2HC_2 PF13913.6 EER29485.1 - 0.25 11.3 5.3 3.1 7.8 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 EER29485.1 - 0.33 10.7 6.7 5.4 6.9 0.5 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type M_domain PF12938.7 EER29485.1 - 0.92 9.2 17.0 0.18 11.6 12.6 2.0 2 0 0 2 2 2 0 M domain of GW182 Fungal_trans PF04082.18 EER29486.1 - 4.5e-11 42.3 0.3 7.1e-11 41.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain V-SNARE_C PF12352.8 EER29487.1 - 0.073 13.4 3.9 0.21 11.9 0.8 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Sec1 PF00995.23 EER29488.1 - 7.4e-122 408.5 0.0 8.3e-122 408.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family E1_4HB PF16191.5 EER29488.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 four-helix bundle Telomere_reg-2 PF10193.9 EER29489.1 - 7.8e-29 100.3 0.2 3.3e-28 98.3 0.0 2.2 3 0 0 3 3 3 1 Telomere length regulation protein DUF2729 PF10870.8 EER29489.1 - 0.22 11.4 0.0 9.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2729) ThiF PF00899.21 EER29490.1 - 3.3e-66 223.1 0.0 4.7e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EER29490.1 - 1.9e-30 104.8 0.1 3.1e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EER29490.1 - 0.0011 19.1 1.1 0.0016 18.5 0.1 1.8 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 EER29490.1 - 0.031 15.0 0.0 0.07 13.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin fold domain Ecm33 PF12454.8 EER29490.1 - 0.035 14.3 2.0 0.07 13.3 2.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.27 EER29490.1 - 0.058 14.0 0.1 0.18 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_thiolCys PF10585.9 EER29490.1 - 0.061 13.2 1.4 2.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-activating enzyme active site Sacchrp_dh_NADP PF03435.18 EER29490.1 - 0.085 13.1 0.3 1.2 9.4 0.0 2.8 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain PglD_N PF17836.1 EER29490.1 - 0.27 11.9 1.2 0.64 10.7 0.6 2.0 1 1 1 2 2 2 0 PglD N-terminal domain RNA_pol_A_bac PF01000.26 EER29491.1 - 1.5e-25 89.8 0.0 3.2e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EER29491.1 - 5.5e-18 64.2 0.0 8.3e-18 63.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 EER29492.1 - 4.7e-125 416.2 0.0 6.6e-125 415.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EER29492.1 - 0.0077 15.2 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase UQ_con PF00179.26 EER29493.1 - 3.2e-25 88.4 0.1 3.9e-25 88.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EER29493.1 - 0.00038 20.2 0.0 0.00049 19.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EER29493.1 - 0.0039 17.5 0.0 0.0047 17.2 0.0 1.2 1 0 0 1 1 1 1 RWD domain Pkinase PF00069.25 EER29494.1 - 5.6e-68 229.2 0.0 7.7e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29494.1 - 2.8e-34 118.6 0.2 4.5e-34 117.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EER29494.1 - 1.7e-06 27.6 0.0 2.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EER29494.1 - 0.001 17.9 0.7 0.0017 17.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EER29494.1 - 0.004 16.5 0.1 0.0085 15.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EER29494.1 - 0.0063 16.1 0.2 0.047 13.2 0.0 2.5 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL Pkinase PF00069.25 EER29496.1 - 4.9e-56 190.0 0.0 6.7e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29496.1 - 4.3e-41 140.9 0.0 6.3e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER29496.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EER29496.1 - 0.01 14.6 0.0 0.021 13.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EER29496.1 - 0.023 14.6 0.0 0.078 12.9 0.0 2.0 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EER29496.1 - 0.033 13.8 0.3 0.13 11.8 0.3 1.9 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 EER29496.1 - 0.037 13.4 0.1 0.072 12.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EER29496.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Aminotran_1_2 PF00155.21 EER29497.1 - 1.7e-17 63.6 0.0 2.2e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EER29497.1 - 0.0023 16.8 0.0 0.0054 15.6 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Fungal_trans PF04082.18 EER29498.1 - 1.4e-18 66.9 0.0 4e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29498.1 - 4.4e-09 36.3 11.6 7.1e-09 35.6 11.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prefoldin_2 PF01920.20 EER29499.1 - 2e-24 85.6 8.8 2.4e-24 85.3 8.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF2089 PF09862.9 EER29499.1 - 0.0097 15.9 2.6 0.039 14.0 0.3 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF2089) DUF2205 PF10224.9 EER29499.1 - 0.016 15.2 1.7 0.016 15.2 1.7 2.0 2 0 0 2 2 2 0 Short coiled-coil protein Prefoldin PF02996.17 EER29499.1 - 0.017 15.1 6.6 0.091 12.7 0.3 2.2 1 1 2 3 3 3 0 Prefoldin subunit DUF4795 PF16043.5 EER29499.1 - 0.039 13.6 8.3 0.43 10.2 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) SAS-6_N PF16531.5 EER29499.1 - 0.04 14.5 0.3 0.059 14.0 0.3 1.6 1 1 0 1 1 1 0 Centriolar protein SAS N-terminal DASH_Dad3 PF08656.10 EER29499.1 - 0.062 13.4 1.7 0.26 11.4 0.4 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF840 PF05801.11 EER29499.1 - 0.076 13.1 0.0 0.096 12.8 0.0 1.2 1 0 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) p25-alpha PF05517.12 EER29499.1 - 0.13 12.4 2.3 1.1 9.4 0.2 2.0 2 0 0 2 2 2 0 p25-alpha CBFD_NFYB_HMF PF00808.23 EER29500.1 - 1.4e-28 98.9 0.6 2e-28 98.4 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EER29500.1 - 6.8e-07 29.7 0.1 1.1e-06 29.0 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EER29500.1 - 0.0027 17.7 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EER29500.1 - 0.0049 17.0 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-18kDa PF02269.16 EER29500.1 - 0.0062 16.5 0.0 0.0091 16.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Sel_put PF04328.13 EER29500.1 - 0.012 15.7 0.6 0.028 14.5 0.6 1.6 1 0 0 1 1 1 0 Selenoprotein, putative Apolipo_F PF15148.6 EER29500.1 - 0.12 11.8 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Apolipoprotein F TFIID_20kDa PF03847.13 EER29500.1 - 0.14 12.6 0.0 0.28 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF3720 PF12517.8 EER29500.1 - 5 8.1 11.5 0.22 12.5 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) HA2 PF04408.23 EER29501.1 - 1.9e-21 76.4 0.9 6.1e-21 74.7 0.0 2.4 3 0 0 3 3 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EER29501.1 - 6.2e-17 61.7 0.0 2.4e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EER29501.1 - 2.6e-15 56.7 0.0 9e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EER29501.1 - 1.8e-06 27.8 0.0 4.6e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EER29501.1 - 0.00034 20.9 0.1 0.00084 19.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EER29501.1 - 0.0007 18.9 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EER29501.1 - 0.0012 18.6 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EER29501.1 - 0.0019 17.3 0.0 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.6 EER29501.1 - 0.0029 17.9 0.1 0.0073 16.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EER29501.1 - 0.014 15.5 0.1 0.058 13.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EER29501.1 - 0.024 14.3 0.4 0.065 12.9 0.4 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.15 EER29501.1 - 0.031 14.3 0.0 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EER29501.1 - 0.041 13.9 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain ATPase PF06745.13 EER29501.1 - 0.041 13.2 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EER29501.1 - 0.061 13.2 1.1 1.1 9.1 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 EER29501.1 - 0.11 12.9 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EER29501.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EER29501.1 - 0.18 11.9 2.8 0.23 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EER29501.1 - 0.23 11.9 0.9 1.7 9.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain DAD PF02109.16 EER29502.1 - 8.2e-47 158.0 0.3 1.1e-46 157.6 0.3 1.2 1 0 0 1 1 1 1 DAD family Tmemb_14 PF03647.13 EER29503.1 - 5.6e-23 81.5 7.3 6.9e-23 81.2 7.3 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C RTC4 PF14474.6 EER29504.1 - 1.5e-32 112.3 0.0 2.5e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain hGDE_N PF14699.6 EER29504.1 - 0.14 12.3 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme DUF726 PF05277.12 EER29505.1 - 1e-126 422.5 2.3 1.4e-126 422.1 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3145 PF11343.8 EER29505.1 - 0.049 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) FMO-like PF00743.19 EER29506.1 - 1.1e-15 57.0 0.1 4e-15 55.2 0.1 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EER29506.1 - 9.3e-12 44.8 0.0 3.1e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER29506.1 - 1.2e-11 44.6 0.0 5e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EER29506.1 - 1e-10 41.4 0.0 2.5e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER29506.1 - 3.6e-06 26.3 0.0 4.7e-05 22.7 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EER29506.1 - 0.00036 20.2 0.1 0.19 11.3 0.0 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EER29506.1 - 0.00037 19.9 0.1 0.003 17.0 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 EER29506.1 - 0.0026 17.8 0.0 0.25 11.3 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EER29506.1 - 0.003 18.1 0.2 1.5 9.4 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER29506.1 - 0.0046 16.2 0.2 0.027 13.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EER29506.1 - 0.011 14.8 0.0 7.2 5.6 0.0 3.2 4 0 0 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EER29506.1 - 0.018 14.2 0.0 0.6 9.1 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EER29506.1 - 0.019 13.7 0.7 3 6.4 0.1 2.4 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EER29506.1 - 0.028 13.5 0.1 22 4.0 0.1 3.0 3 0 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.20 EER29506.1 - 0.044 13.8 0.1 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EER29506.1 - 0.054 13.7 0.1 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EER29506.1 - 0.25 11.2 0.1 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain APH PF01636.23 EER29507.1 - 4.8e-20 72.5 0.8 6.7e-20 72.0 0.8 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EER29507.1 - 0.00073 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EER29507.1 - 0.06 12.9 0.0 0.077 12.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LicD PF04991.13 EER29508.1 - 6e-22 78.9 5.3 1e-14 55.3 1.5 2.2 1 1 1 2 2 2 2 LicD family Fungal_trans PF04082.18 EER29509.1 - 7.1e-16 58.0 0.0 1.2e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29509.1 - 6.9e-09 35.7 12.3 1.3e-08 34.8 12.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EER29510.1 - 1.3e-31 109.8 50.9 7.5e-30 104.0 19.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER29510.1 - 4.1e-12 45.7 1.3 4.1e-12 45.7 1.3 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter ExoD PF06055.12 EER29510.1 - 0.0032 16.9 1.1 0.0032 16.9 1.1 2.3 2 1 1 3 3 3 1 Exopolysaccharide synthesis, ExoD MFS_1_like PF12832.7 EER29510.1 - 0.0037 16.2 1.1 0.0037 16.2 1.1 2.9 2 1 0 2 2 2 1 MFS_1 like family TRI12 PF06609.13 EER29510.1 - 0.0051 15.3 0.3 0.0051 15.3 0.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2754 PF10953.8 EER29510.1 - 3.3 8.0 7.6 0.41 10.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) TFR_dimer PF04253.15 EER29511.1 - 6.6e-34 116.6 0.1 1.1e-33 115.9 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EER29511.1 - 3.4e-21 75.8 0.0 6.9e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EER29511.1 - 3.3e-09 36.6 0.1 8.4e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 EER29511.1 - 0.0019 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Nicastrin zf-C2H2_4 PF13894.6 EER29512.1 - 3.4e-06 27.4 5.5 0.0082 16.9 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EER29512.1 - 0.012 16.1 0.1 0.012 16.1 0.1 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EER29512.1 - 1.1 9.3 5.5 0.31 11.1 0.4 2.6 2 1 1 3 3 3 0 C2H2-type zinc finger CMD PF02627.20 EER29514.1 - 1.1e-06 28.6 0.2 0.00034 20.6 0.0 2.4 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family DUF5427 PF10310.9 EER29515.1 - 2.2e-167 557.7 0.0 2.7e-167 557.4 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 EER29515.1 - 0.17 12.1 0.4 0.47 10.7 0.4 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Zn_clus PF00172.18 EER29516.1 - 0.00016 21.7 4.6 0.0004 20.4 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC37_N PF03234.14 EER29517.1 - 0.043 14.7 0.2 0.15 13.0 0.2 1.9 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Allexi_40kDa PF05549.11 EER29517.1 - 0.099 12.1 0.3 0.22 11.0 0.3 1.5 1 0 0 1 1 1 0 Allexivirus 40kDa protein GAS PF13851.6 EER29517.1 - 0.16 11.3 7.5 0.49 9.7 7.4 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 EER29517.1 - 0.43 10.0 8.8 0.85 9.0 8.8 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Cnn_1N PF07989.11 EER29517.1 - 0.45 10.7 7.0 0.21 11.8 4.3 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Pox_A_type_inc PF04508.12 EER29517.1 - 0.53 10.2 3.3 1.6 8.7 0.8 3.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Macoilin PF09726.9 EER29517.1 - 0.59 8.6 6.5 1.1 7.8 6.5 1.4 1 0 0 1 1 1 0 Macoilin family Tropomyosin_1 PF12718.7 EER29517.1 - 2.4 8.3 12.8 5.1 7.2 12.0 1.9 1 1 1 2 2 2 0 Tropomyosin like HNH_2 PF13391.6 EER29518.1 - 2.5e-15 56.4 0.3 2.5e-15 56.4 0.3 2.4 3 0 0 3 3 3 1 HNH endonuclease GPI-anchored PF10342.9 EER29519.1 - 7.2e-22 78.0 0.5 7.2e-22 78.0 0.5 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Aldedh PF00171.22 EER29520.1 - 5.2e-133 443.9 0.2 6.3e-133 443.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IBN_N PF03810.19 EER29521.1 - 1.8e-13 50.2 0.1 2.8e-12 46.4 0.0 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EER29521.1 - 0.00034 20.7 3.5 0.017 15.2 0.1 3.1 3 0 0 3 3 3 2 Exportin 1-like protein Pex2_Pex12 PF04757.14 EER29522.1 - 8.7e-39 133.4 0.4 1.2e-38 132.9 0.4 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EER29522.1 - 0.00025 21.2 4.7 0.00048 20.2 4.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EER29522.1 - 0.0042 17.1 1.1 0.019 15.0 1.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EER29522.1 - 0.04 13.8 0.8 0.094 12.6 0.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER29522.1 - 0.081 12.8 2.9 0.15 11.9 0.6 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1772 PF08592.11 EER29523.1 - 2.7e-31 108.7 0.8 3.5e-31 108.3 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.6 EER29523.1 - 0.1 11.7 1.1 0.27 10.3 1.1 1.8 1 1 0 1 1 1 0 Transmembrane protein 237 ILVD_EDD PF00920.21 EER29524.1 - 3.4e-209 695.7 1.8 4e-209 695.5 1.8 1.0 1 0 0 1 1 1 1 Dehydratase family Abhydrolase_6 PF12697.7 EER29525.1 - 1.7e-15 58.3 0.1 4.9e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER29525.1 - 2.5e-15 56.8 0.1 1.2e-14 54.6 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EER29525.1 - 3.6e-10 39.5 0.0 1.2e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DSPc PF00782.20 EER29525.1 - 4.4e-09 36.2 0.0 9.5e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Lipase_3 PF01764.25 EER29525.1 - 0.00019 21.3 0.4 0.00072 19.4 0.1 1.9 1 1 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.13 EER29525.1 - 0.00046 20.0 0.0 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein PTPlike_phytase PF14566.6 EER29525.1 - 0.00057 20.0 0.0 0.00097 19.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Thioesterase PF00975.20 EER29525.1 - 0.0019 18.4 0.1 0.0035 17.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain LIDHydrolase PF10230.9 EER29525.1 - 0.0022 17.6 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF676 PF05057.14 EER29525.1 - 0.0026 17.3 0.0 0.012 15.1 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Ser_hydrolase PF06821.13 EER29525.1 - 0.018 14.9 0.1 0.046 13.6 0.1 1.6 2 0 0 2 2 1 0 Serine hydrolase LCAT PF02450.15 EER29525.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FSH1 PF03959.13 EER29525.1 - 0.055 13.1 0.0 0.69 9.5 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Y_phosphatase PF00102.27 EER29525.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PAF-AH_p_II PF03403.13 EER29525.1 - 0.086 11.3 0.2 1.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Ribosomal_S19e PF01090.19 EER29526.1 - 4.1e-59 198.2 0.1 4.6e-59 198.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Aldo_ket_red PF00248.21 EER29527.1 - 2.8e-42 144.9 0.0 7.3e-40 137.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 EER29527.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain eRF1_1 PF03463.15 EER29529.1 - 5.3e-48 162.3 0.1 8.3e-48 161.6 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EER29529.1 - 5.2e-18 65.6 0.0 1.1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EER29529.1 - 2.9e-16 60.0 0.0 5.5e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 LptE PF04390.12 EER29529.1 - 0.059 14.1 0.0 0.17 12.6 0.0 1.9 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Lysis_col PF02402.16 EER29529.1 - 2.3 8.0 4.2 16 5.3 0.1 2.5 2 0 0 2 2 2 0 Lysis protein Myb_DNA-bind_4 PF13837.6 EER29530.1 - 0.00028 21.2 5.4 0.043 14.2 2.4 2.4 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.31 EER29530.1 - 0.017 15.3 4.3 0.087 13.0 2.3 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 EER29530.1 - 0.023 14.8 0.7 0.023 14.8 0.7 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_3 PF12776.7 EER29530.1 - 0.025 15.5 3.9 0.58 11.2 0.1 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER29530.1 - 1.3 9.4 7.8 1.9 8.8 4.4 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER29531.1 - 0.00028 21.1 0.1 0.29 11.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EER29531.1 - 0.0013 18.9 1.0 0.0066 16.6 0.8 2.3 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EER29532.1 - 1.1e-15 57.5 3.4 1.6e-09 37.8 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EER29532.1 - 5.2e-11 42.6 1.2 1.9e-06 28.0 0.2 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EER29532.1 - 0.013 15.4 0.6 0.024 14.5 0.3 1.4 1 1 0 1 1 1 0 Myb DNA-binding like COX5B PF01215.19 EER29533.1 - 1.6e-53 179.8 0.0 2e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Myb_DNA-bind_6 PF13921.6 EER29534.1 - 8.3e-14 51.6 0.0 1.4e-07 31.6 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EER29534.1 - 4.7e-12 45.9 0.1 4e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EER29534.1 - 0.085 13.1 0.4 3.4 7.9 0.2 2.1 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 PEPCK_N PF17297.2 EER29535.1 - 0.031 13.9 0.0 0.042 13.5 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain PROCN PF08083.11 EER29536.1 - 1e-235 782.0 8.5 1e-235 782.0 8.5 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EER29536.1 - 1.9e-126 420.3 2.1 3.4e-126 419.5 2.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EER29536.1 - 2.4e-89 297.3 2.0 1e-88 295.3 2.0 2.2 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EER29536.1 - 1e-80 269.0 1.3 1e-80 269.0 1.3 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EER29536.1 - 5.7e-71 236.8 0.1 1.2e-70 235.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EER29536.1 - 4.8e-49 165.4 0.8 9.5e-49 164.4 0.1 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 EER29536.1 - 4.1e-48 161.7 0.3 1.2e-47 160.2 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Ribosomal_L34e PF01199.18 EER29537.1 - 1e-42 144.3 2.9 1.5e-42 143.8 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EER29537.1 - 0.035 13.5 1.1 0.049 13.0 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 EER29537.1 - 7.5 6.6 8.4 3.5 7.7 0.3 2.8 2 1 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Forkhead PF00250.18 EER29538.1 - 4.6e-20 71.7 0.0 9.1e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 EER29539.1 - 1.1e-66 224.3 4.0 2.2e-66 223.4 4.0 1.5 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EER29539.1 - 4.1e-57 191.5 7.7 7.4e-57 190.7 7.7 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein XLF PF09302.11 EER29540.1 - 2.1e-50 171.3 0.3 4.5e-50 170.3 0.3 1.5 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component WD40 PF00400.32 EER29541.1 - 2.2e-14 53.6 9.1 2.3e-06 28.2 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER29541.1 - 4.5e-06 26.9 0.2 0.86 10.0 0.0 3.6 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EER29541.1 - 0.0094 15.9 0.0 0.096 12.6 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A ABC_membrane PF00664.23 EER29542.1 - 1.9e-36 126.1 9.5 1.9e-36 126.1 9.5 2.6 3 0 0 3 3 3 1 ABC transporter transmembrane region ABC_tran PF00005.27 EER29542.1 - 1.2e-31 110.0 0.0 4.3e-31 108.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EER29542.1 - 7.4e-07 28.8 0.0 4.4e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.7 EER29542.1 - 0.02 13.8 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 EER29542.1 - 0.022 15.0 0.0 0.14 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EER29542.1 - 0.033 14.4 1.7 0.46 10.7 0.4 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EER29542.1 - 0.034 13.9 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3989 PF13150.6 EER29542.1 - 0.056 13.2 0.0 7.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) AAA_16 PF13191.6 EER29542.1 - 0.27 11.6 1.8 1.7 9.0 1.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain Pex24p PF06398.11 EER29542.1 - 0.53 9.2 4.2 0.14 11.1 1.1 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF498 PF04430.14 EER29543.1 - 5.5e-33 113.3 0.0 7.5e-33 112.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF2457 PF10446.9 EER29543.1 - 0.12 11.5 3.5 0.16 11.1 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Alk_phosphatase PF00245.20 EER29544.1 - 2.9e-108 362.5 0.0 3.8e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EER29544.1 - 5.4e-05 22.7 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Glyco_hydro_16 PF00722.21 EER29545.1 - 3.5e-45 153.6 1.7 5e-45 153.1 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EER29545.1 - 0.1 13.1 15.3 0.21 12.1 15.3 1.5 1 0 0 1 1 1 0 Chitin recognition protein GIT1_C PF12205.8 EER29546.1 - 0.069 13.3 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Pro_dh PF01619.18 EER29547.1 - 8.7e-66 222.4 0.0 1.1e-65 222.2 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase PMSR PF01625.21 EER29548.1 - 6.5e-63 211.5 0.2 7.8e-63 211.2 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Gln-synt_C PF00120.24 EER29548.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain Kinesin PF00225.23 EER29549.1 - 4.3e-116 387.5 0.0 6.7e-116 386.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EER29549.1 - 3.8e-26 91.8 1.2 4.7e-26 91.5 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Herpes_UL14 PF03580.14 EER29549.1 - 0.0084 16.4 1.6 0.024 14.9 1.6 1.8 1 0 0 1 1 1 1 Herpesvirus UL14-like protein AAA_33 PF13671.6 EER29549.1 - 0.018 15.2 0.1 0.29 11.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain Met_synt_B12 PF02965.17 EER29549.1 - 2.4 7.6 4.9 0.46 9.9 0.5 1.8 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain Tim17 PF02466.19 EER29551.1 - 0.0023 18.3 1.8 0.0035 17.7 1.8 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Con-6 PF10346.9 EER29553.1 - 2.5e-31 107.4 8.3 1.9e-15 56.6 1.1 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.7 EER29553.1 - 0.067 13.0 2.4 1.7 8.4 0.2 2.1 1 1 1 2 2 2 0 SpoIIIAH-like protein TetR_C_28 PF17937.1 EER29553.1 - 0.25 11.8 3.3 1.1 9.8 0.3 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ARGLU PF15346.6 EER29553.1 - 1.7 8.5 14.0 1.6e+02 2.1 14.0 2.2 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 cNMP_binding PF00027.29 EER29555.1 - 6.7e-36 122.2 0.0 1.3e-21 76.4 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMPbd_u2 PF16643.5 EER29555.1 - 7.9e-35 120.6 6.6 1.6e-34 119.7 6.6 1.5 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein F-box PF00646.33 EER29555.1 - 3e-07 30.1 7.0 4.1e-07 29.7 1.1 3.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EER29555.1 - 5.3e-05 23.0 0.8 5.3e-05 23.0 0.8 2.4 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.6 EER29555.1 - 0.00092 19.1 0.5 6.7 7.0 0.0 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 EER29555.1 - 0.0016 18.8 5.0 31 5.2 0.0 5.5 5 2 1 6 6 6 0 Leucine Rich repeats (2 copies) SAM_Ste50p PF09235.10 EER29555.1 - 0.017 15.4 0.6 6.2 7.1 0.0 3.8 3 1 1 4 4 4 0 Ste50p, sterile alpha motif Slx4 PF09494.10 EER29556.1 - 9.6e-27 92.7 0.5 1.6e-26 92.0 0.5 1.4 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.10 EER29557.1 - 1.6e-51 174.7 0.1 1.8e-51 174.5 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.20 EER29558.1 - 1.2e-31 110.1 10.0 1.9e-31 109.5 10.0 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Alpha-amylase PF00128.24 EER29559.1 - 1.8e-29 103.4 0.1 1.7e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF1966 PF09260.11 EER29559.1 - 9.3e-18 64.3 0.0 1.9e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) RRM_1 PF00076.22 EER29560.1 - 8.4e-17 60.8 0.1 1.4e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EER29560.1 - 0.00036 20.1 0.0 0.0006 19.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.14 EER29561.1 - 5.3e-23 82.1 0.0 9.5e-16 58.3 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 DUF2205 PF10224.9 EER29562.1 - 3.4e-34 116.7 1.3 5.7e-34 116.0 1.3 1.4 1 0 0 1 1 1 1 Short coiled-coil protein Macoilin PF09726.9 EER29562.1 - 0.0025 16.5 3.9 0.003 16.2 3.9 1.0 1 0 0 1 1 1 1 Macoilin family CENP-F_leu_zip PF10473.9 EER29562.1 - 0.004 17.2 1.0 0.006 16.6 1.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.17 EER29562.1 - 0.0063 16.4 1.3 0.011 15.6 1.3 1.4 1 0 0 1 1 1 1 Prefoldin subunit HALZ PF02183.18 EER29562.1 - 0.0076 16.5 3.0 0.24 11.7 0.1 2.3 1 1 1 2 2 2 1 Homeobox associated leucine zipper PI3K_P85_iSH2 PF16454.5 EER29562.1 - 0.011 15.3 1.1 0.019 14.6 1.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TPR_MLP1_2 PF07926.12 EER29562.1 - 0.012 15.6 1.6 0.012 15.6 1.6 1.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 EER29562.1 - 0.015 15.9 0.6 0.024 15.2 0.6 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 EER29562.1 - 0.021 14.6 1.0 0.037 13.8 1.0 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF5320 PF17253.2 EER29562.1 - 0.029 15.4 0.5 0.086 13.9 0.2 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) IFT20 PF14931.6 EER29562.1 - 0.04 14.1 1.4 0.08 13.1 1.4 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 LCD1 PF09798.9 EER29562.1 - 0.18 10.3 1.6 0.23 9.9 1.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein bZIP_1 PF00170.21 EER29562.1 - 0.19 11.9 3.7 0.69 10.1 4.2 1.7 1 1 1 2 2 2 0 bZIP transcription factor JIP_LZII PF16471.5 EER29562.1 - 0.21 11.7 2.7 0.54 10.5 1.7 1.9 1 1 0 1 1 1 0 JNK-interacting protein leucine zipper II CCDC106 PF15794.5 EER29562.1 - 0.26 11.0 6.9 3.2 7.4 1.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DUF3958 PF13125.6 EER29562.1 - 0.29 11.3 4.0 0.9 9.8 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Myf5 PF12232.8 EER29562.1 - 0.99 10.2 10.8 9.4 7.1 6.9 2.6 2 1 0 2 2 2 0 Myogenic determination factor 5 14-3-3 PF00244.20 EER29563.1 - 9.3e-107 355.6 6.3 1.1e-106 355.4 6.3 1.0 1 0 0 1 1 1 1 14-3-3 protein TerB PF05099.13 EER29563.1 - 0.035 14.1 0.3 0.093 12.7 0.3 1.7 1 0 0 1 1 1 0 Tellurite resistance protein TerB IATP PF04568.12 EER29564.1 - 3.8e-29 101.0 1.2 4.3e-29 100.8 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP BLOC1_2 PF10046.9 EER29564.1 - 0.019 15.3 1.9 0.025 14.9 1.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TssO PF17561.2 EER29564.1 - 0.036 14.2 1.6 0.045 13.9 1.6 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssO PKHD_C PF18331.1 EER29564.1 - 0.056 13.5 0.2 0.13 12.3 0.2 1.6 1 0 0 1 1 1 0 PKHD-type hydroxylase C-terminal domain DUF4140 PF13600.6 EER29564.1 - 0.057 13.9 0.2 0.068 13.6 0.2 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 EER29564.1 - 0.2 11.4 3.8 0.32 10.8 3.8 1.3 1 0 0 1 1 1 0 Septum formation initiator Nsp1_C PF05064.13 EER29565.1 - 4.2e-39 132.9 2.6 9.1e-39 131.9 2.6 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EER29565.1 - 5.7e-09 36.7 122.5 0.00043 21.1 9.8 5.7 1 1 4 5 5 4 3 Nucleoporin FG repeat region AAA_13 PF13166.6 EER29565.1 - 0.035 12.8 4.4 0.052 12.2 4.4 1.1 1 0 0 1 1 1 0 AAA domain IMS_C PF11799.8 EER29565.1 - 0.037 14.7 0.1 0.095 13.4 0.1 1.6 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Baculo_PEP_C PF04513.12 EER29565.1 - 0.052 13.6 3.7 0.065 13.3 2.3 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ParB PF08775.10 EER29565.1 - 0.097 13.1 0.4 0.097 13.1 0.4 1.9 2 0 0 2 2 2 0 ParB family Laminin_I PF06008.14 EER29565.1 - 0.36 10.5 9.3 0.4 10.3 0.5 1.9 1 1 1 2 2 2 0 Laminin Domain I HIP1_clath_bdg PF16515.5 EER29565.1 - 1.3 9.7 10.2 8.8 7.0 0.4 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1664 PF07889.12 EER29565.1 - 1.3 9.1 6.4 1.4 9.0 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 EER29565.1 - 1.6 7.6 9.2 0.49 9.3 3.4 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4200 PF13863.6 EER29565.1 - 1.6 9.1 10.8 1.3 9.4 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) FlaC_arch PF05377.11 EER29565.1 - 2 8.9 3.7 9.8 6.7 0.1 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF724 PF05266.14 EER29565.1 - 2.6 7.8 5.1 0.98 9.2 1.6 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF724) OmpH PF03938.14 EER29565.1 - 4.6 7.6 13.6 2.4 8.5 0.2 2.3 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF5102 PF17104.5 EER29566.1 - 4.9e-112 374.7 3.4 8.5e-112 373.9 3.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) zf-MIZ PF02891.20 EER29567.1 - 9.1e-11 41.3 0.1 2.2e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger LIN37 PF15306.6 EER29567.1 - 3.1 8.0 9.4 0.11 12.7 0.6 2.8 2 1 1 3 3 3 0 LIN37 PH PF00169.29 EER29568.1 - 8.8e-10 39.0 0.0 1.3e-08 35.3 0.0 2.4 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 EER29568.1 - 2e-08 33.7 0.0 3.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 EER29568.1 - 7.9e-08 32.3 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 EER29568.1 - 8.3e-07 28.8 0.1 1.6e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 EER29568.1 - 0.00081 19.8 0.1 0.0016 18.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 EER29568.1 - 0.0017 18.7 0.0 0.0069 16.8 0.0 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.17 EER29568.1 - 0.0032 17.1 0.1 0.0067 16.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 EER29568.1 - 0.059 13.7 0.1 0.24 11.7 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Ribosomal_L14 PF00238.19 EER29570.1 - 2.7e-34 117.9 0.0 3.2e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 EER29570.1 - 0.088 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Hist_deacetyl PF00850.19 EER29571.1 - 4.9e-82 275.8 0.0 9.3e-82 274.9 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 EER29572.1 - 7.1e-33 113.1 0.0 1.6e-32 111.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EER29572.1 - 2.9e-12 47.0 0.8 5.1e-12 46.2 0.8 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EER29572.1 - 2.3e-07 30.6 0.0 7.2e-07 29.0 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain NIF PF03031.18 EER29573.1 - 5.1e-41 140.0 0.0 7.2e-41 139.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Beta_elim_lyase PF01212.21 EER29574.1 - 9.1e-67 225.4 0.0 1.1e-66 225.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EER29574.1 - 0.00017 20.9 0.0 0.0016 17.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EER29574.1 - 0.059 12.7 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.18 EER29575.1 - 8.4e-14 51.2 0.0 2.1e-13 49.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29575.1 - 1.7e-06 28.1 6.8 4e-06 26.9 6.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EER29576.1 - 0.0058 16.5 0.3 0.016 15.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER29576.1 - 0.0074 16.2 0.2 0.016 15.0 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EER29576.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 F-box GRDP-like PF07173.12 EER29577.1 - 2.1e-17 64.1 2.1 2.3e-13 51.0 0.0 2.8 3 0 0 3 3 3 2 Glycine-rich domain-containing protein-like M20_dimer PF07687.14 EER29577.1 - 0.16 11.9 0.0 7 6.6 0.0 2.5 2 0 0 2 2 2 0 Peptidase dimerisation domain Fungal_trans PF04082.18 EER29578.1 - 1.8e-10 40.3 0.2 3e-10 39.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29578.1 - 5.4e-06 26.4 9.9 5.4e-06 26.4 9.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.17 EER29579.1 - 2.1e-30 105.9 0.0 3e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EER29579.1 - 7.3e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EER29579.1 - 0.011 15.3 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 0 Nicastrin AAA_29 PF13555.6 EER29579.1 - 0.032 14.0 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_S8 PF00082.22 EER29581.1 - 3.5e-17 62.6 0.0 4.2e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 Subtilase family Pkinase PF00069.25 EER29582.1 - 3e-68 230.1 0.0 5.7e-68 229.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29582.1 - 3.2e-33 115.1 0.0 1.1e-31 110.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER29582.1 - 0.0017 17.7 0.1 1.8 7.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 EER29582.1 - 0.019 14.6 0.5 0.032 13.8 0.5 1.4 1 0 0 1 1 1 0 RIO1 family HAMP PF00672.25 EER29583.1 - 6.9e-39 132.0 19.1 4.5e-09 36.5 0.0 8.9 8 2 2 10 10 10 5 HAMP domain HATPase_c PF02518.26 EER29583.1 - 4.3e-33 114.2 0.5 1.6e-32 112.4 0.2 2.2 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EER29583.1 - 2.6e-25 88.8 0.5 1.2e-24 86.7 0.5 2.3 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EER29583.1 - 4e-17 62.0 3.8 2.2e-16 59.7 0.1 4.0 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 EER29583.1 - 4e-06 27.0 0.2 2.9 8.1 0.0 6.0 6 1 0 6 6 6 1 Domain of unknown function (DUF4279) DUF948 PF06103.11 EER29583.1 - 0.00066 19.9 47.1 0.75 10.1 4.4 9.8 4 2 3 8 8 8 3 Bacterial protein of unknown function (DUF948) DUF1843 PF08898.10 EER29583.1 - 0.0014 19.1 4.8 17 6.0 0.1 5.9 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) HATPase_c_3 PF13589.6 EER29583.1 - 0.0044 16.9 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3829 PF12889.7 EER29583.1 - 0.0076 15.8 0.4 0.0076 15.8 0.4 5.1 4 2 2 6 6 6 1 Protein of unknown function (DUF3829) CMD PF02627.20 EER29583.1 - 0.025 14.6 1.0 12 6.0 0.0 4.1 5 0 0 5 5 4 0 Carboxymuconolactone decarboxylase family SpoIIID PF12116.8 EER29583.1 - 0.04 14.0 1.7 22 5.2 0.0 4.6 4 1 0 4 4 4 0 Stage III sporulation protein D AdHead_fibreRBD PF16812.5 EER29583.1 - 0.11 12.3 0.1 0.11 12.3 0.1 3.7 4 0 0 4 4 4 0 C-terminal head domain of the fowl adenovirus type 1 long fibre DnaB_bind PF10410.9 EER29583.1 - 0.16 12.2 0.3 24 5.2 0.0 3.4 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Atg14 PF10186.9 EER29583.1 - 1.5 7.8 8.8 5.2 6.0 6.4 2.5 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fib_alpha PF08702.10 EER29583.1 - 2.2 8.4 39.3 0.49 10.6 1.1 7.1 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family DUF5593 PF18007.1 EER29583.1 - 2.5 8.9 4.6 78 4.1 0.1 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5593) AvrB_AvrC PF05394.11 EER29583.1 - 6.5 5.8 7.2 31 3.6 3.2 2.3 2 0 0 2 2 2 0 Avirulence protein Amino_oxidase PF01593.24 EER29585.1 - 2.8e-15 56.6 0.1 2e-14 53.7 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EER29585.1 - 1.4e-10 41.2 0.1 2.8e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EER29585.1 - 8.5e-09 35.3 0.2 1e-07 31.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EER29585.1 - 3.1e-05 24.4 2.7 0.0076 16.8 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EER29585.1 - 0.00013 21.2 0.4 0.00013 21.2 0.4 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EER29585.1 - 0.00016 21.1 0.2 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EER29585.1 - 0.0004 20.1 1.6 0.0036 16.9 0.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER29585.1 - 0.001 18.4 1.1 0.0048 16.2 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EER29585.1 - 0.0015 17.8 0.2 0.0028 17.0 0.2 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EER29585.1 - 0.0017 17.1 0.3 0.0017 17.1 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.16 EER29585.1 - 0.011 15.3 0.2 0.022 14.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Collar PF07484.12 EER29585.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Phage Tail Collar Domain IlvN PF07991.12 EER29585.1 - 0.14 11.7 0.5 0.71 9.4 0.2 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 EER29585.1 - 0.14 11.2 0.2 0.21 10.6 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EER29585.1 - 0.26 10.5 2.7 0.35 10.1 0.6 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.6 EER29586.1 - 4.4e-29 101.6 29.4 5.5e-29 101.2 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER29586.1 - 4.6e-21 74.9 26.0 9.4e-21 73.9 26.0 1.4 1 1 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 EER29587.1 - 6.5e-33 114.1 63.4 4.7e-27 94.8 42.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER29587.1 - 3.9e-10 39.2 37.6 4.1e-07 29.2 12.8 2.6 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 EER29588.1 - 9e-24 84.0 24.9 3.5e-10 39.4 1.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EER29588.1 - 1.7e-12 46.9 16.4 4.7e-09 35.6 8.8 2.8 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EER29588.1 - 0.12 11.1 8.5 0.026 13.4 1.4 2.6 3 0 0 3 3 3 0 MFS_1 like family tRNA-synt_2d PF01409.20 EER29589.1 - 1.4e-87 293.3 0.0 1.8e-87 292.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EER29589.1 - 6.2e-16 58.4 0.7 1.6e-15 57.1 0.7 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EER29589.1 - 5.2e-05 22.8 0.0 0.068 12.6 0.0 2.5 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EER29589.1 - 0.00013 21.2 0.2 0.0032 16.6 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 EER29589.1 - 0.0023 17.9 1.1 0.0071 16.3 1.1 1.9 1 1 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_His PF13393.6 EER29589.1 - 0.24 10.6 0.5 3.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Ribosomal_S21e PF01249.18 EER29590.1 - 6.7e-42 141.5 0.0 7.5e-42 141.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.28 EER29591.1 - 1.2e-08 35.1 0.0 4.1e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.25 EER29592.1 - 2.9e-128 427.7 3.0 3.4e-128 427.5 3.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EER29592.1 - 2.6e-19 69.4 0.1 3.7e-10 40.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EER29592.1 - 1.1e-06 27.9 0.5 2.1e-06 27.0 0.5 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EER29592.1 - 1.1e-05 25.0 6.8 0.018 14.4 4.6 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EER29592.1 - 0.00086 18.8 2.6 8.8 5.7 0.2 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.21 EER29592.1 - 0.0066 15.4 0.0 0.018 13.9 0.0 1.6 1 1 1 2 2 2 1 Pyruvate kinase, barrel domain YpsA PF06908.11 EER29592.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 YspA SLOG family ThiG PF05690.14 EER29592.1 - 0.15 11.4 2.6 0.09 12.1 0.6 1.6 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG RasGAP PF00616.19 EER29593.1 - 4.3e-51 173.6 0.0 1e-50 172.4 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EER29593.1 - 3.9e-50 169.6 3.7 9.9e-50 168.3 3.7 1.8 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 EER29593.1 - 9.8e-18 62.2 59.3 0.092 12.6 0.6 16.2 17 0 0 17 17 17 10 IQ calmodulin-binding motif CH PF00307.31 EER29593.1 - 1.3e-12 47.8 0.0 4e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EER29593.1 - 0.0021 17.9 0.0 0.008 16.0 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain Ead_Ea22 PF13935.6 EER29593.1 - 0.31 11.7 2.5 1.5 9.5 0.1 2.8 2 0 0 2 2 2 0 Ead/Ea22-like protein ENTH PF01417.20 EER29594.1 - 6.1e-46 155.5 0.1 9.3e-46 154.9 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EER29594.1 - 8.5e-05 21.7 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_1 PF00018.28 EER29595.1 - 2.9e-11 42.8 0.0 5.3e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER29595.1 - 5.7e-09 35.7 0.0 1.2e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EER29595.1 - 4.1e-07 29.6 0.0 7.1e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HMG-CoA_red PF00368.18 EER29597.1 - 1.3e-140 468.6 7.1 1.6e-140 468.3 7.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EER29597.1 - 1.5e-49 167.8 0.0 3e-49 166.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EER29597.1 - 1.8e-12 47.4 4.5 3e-11 43.4 4.5 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EER29597.1 - 0.0013 16.9 0.7 0.0013 16.9 0.7 1.7 2 0 0 2 2 2 1 Patched family GIT_SHD PF08518.11 EER29598.1 - 7e-18 63.9 9.1 2.1e-11 43.2 0.7 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 EER29598.1 - 3.1e-05 24.1 0.5 3.1e-05 24.1 0.5 3.2 2 1 1 3 3 3 1 G protein-coupled receptor kinase-interacting protein 1 C term HMMR_N PF15905.5 EER29598.1 - 0.48 9.8 38.1 2 7.8 23.1 2.6 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF3584 PF12128.8 EER29598.1 - 0.62 7.5 35.3 1.1 6.6 35.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Chorion_S16 PF05836.12 EER29598.1 - 2.8 8.2 5.9 29 4.9 5.7 2.6 2 0 0 2 2 2 0 Chorion protein S16 K_channel_TID PF07941.11 EER29598.1 - 3.9 8.0 14.9 0.32 11.5 5.8 3.3 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Pro_isomerase PF00160.21 EER29599.1 - 2.1e-42 145.1 0.4 2.8e-42 144.7 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Flavin_Reduct PF01613.18 EER29599.1 - 0.04 14.0 0.5 0.064 13.3 0.5 1.3 1 0 0 1 1 1 0 Flavin reductase like domain RNase_PH PF01138.21 EER29600.1 - 1.7e-30 106.2 0.0 2.9e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pkinase PF00069.25 EER29601.1 - 2.2e-13 50.2 0.0 1.6e-12 47.3 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29601.1 - 0.0095 15.2 0.0 0.41 9.9 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase SNF2_N PF00176.23 EER29602.1 - 1.5e-51 175.1 0.0 2.5e-51 174.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EER29602.1 - 2e-27 95.1 0.5 6.1e-27 93.5 0.5 1.9 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EER29602.1 - 2.7e-20 72.8 0.0 3.7e-19 69.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EER29602.1 - 6.5e-08 32.1 0.1 1.3e-07 31.1 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EER29602.1 - 2e-05 24.5 0.0 7.1e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EER29602.1 - 7.3e-05 22.8 0.0 0.00026 21.0 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cas_Csy2 PF09614.10 EER29602.1 - 0.13 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) SEC-C PF02810.15 EER29602.1 - 0.97 9.4 13.2 1.9 8.5 13.2 1.5 1 0 0 1 1 1 0 SEC-C motif Rrp44_CSD1 PF17216.3 EER29602.1 - 3.8 7.2 5.5 1.2 8.8 1.8 2.0 2 0 0 2 2 2 0 Rrp44-like cold shock domain Ssu72 PF04722.13 EER29603.1 - 7.5e-82 273.5 0.0 8.7e-82 273.3 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Acyl-CoA_dh_1 PF00441.24 EER29604.1 - 1.5e-18 67.4 1.1 5.4e-18 65.6 1.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EER29604.1 - 1.5e-10 41.2 0.0 3.1e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AidB_N PF18158.1 EER29604.1 - 2.2e-10 40.7 0.0 4.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_2 PF08028.11 EER29604.1 - 0.0079 16.5 0.1 0.03 14.6 0.1 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RE_XamI PF09572.10 EER29604.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 XamI restriction endonuclease AcylCoA_dehyd_C PF12186.8 EER29604.1 - 0.18 11.9 0.1 0.49 10.5 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Isochorismatase PF00857.20 EER29605.1 - 7.6e-23 81.6 0.1 5.2e-22 78.9 0.1 1.9 1 1 0 1 1 1 1 Isochorismatase family DUF3605 PF12239.8 EER29606.1 - 6e-58 195.5 3.5 7.5e-58 195.2 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Oxysterol_BP PF01237.18 EER29607.1 - 9.1e-90 301.2 0.1 2.5e-87 293.1 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Hist_deacetyl PF00850.19 EER29608.1 - 3.4e-78 263.2 0.0 5.4e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.7 EER29609.1 - 1.4e-22 80.2 4.5 2.4e-22 79.4 4.5 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EER29609.1 - 2.7e-05 24.0 9.8 4.9e-05 23.1 9.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EER29609.1 - 0.018 15.3 1.9 0.041 14.1 1.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Prominin PF05478.11 EER29609.1 - 0.16 9.9 1.0 0.19 9.6 1.0 1.1 1 0 0 1 1 1 0 Prominin RNA_pol_Rpc34 PF05158.12 EER29610.1 - 5.2e-111 371.3 0.0 6.4e-111 371.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 EER29610.1 - 0.069 13.5 0.1 0.16 12.3 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator TPR_1 PF00515.28 EER29611.1 - 1e-39 132.7 23.9 1.5e-05 24.6 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EER29611.1 - 9.2e-37 124.8 9.5 1.8e-21 75.8 0.8 2.9 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 EER29611.1 - 1.4e-29 99.8 23.5 0.00012 21.9 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 EER29611.1 - 8.4e-18 63.8 18.8 0.012 15.3 0.4 8.3 6 1 2 8 8 8 6 TPR repeat TPR_8 PF13181.6 EER29611.1 - 2.1e-13 49.3 19.5 0.16 12.2 0.6 8.6 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 EER29611.1 - 2.2e-12 47.3 15.7 0.019 15.4 0.2 6.5 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 EER29611.1 - 1.7e-10 40.9 1.4 0.0013 18.9 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EER29611.1 - 1.8e-09 37.8 15.3 8.4e-05 22.8 0.1 6.3 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 EER29611.1 - 6.2e-09 35.9 16.1 0.27 12.2 0.2 9.0 3 3 6 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.6 EER29611.1 - 2.9e-07 31.0 19.1 0.14 12.9 0.2 6.3 3 3 2 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 EER29611.1 - 3.4e-07 30.2 6.1 0.74 10.3 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EER29611.1 - 1.1e-06 28.2 5.4 0.27 11.3 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EER29611.1 - 2.4e-05 24.0 9.3 0.082 12.8 0.1 6.4 6 1 1 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EER29611.1 - 0.00066 19.9 10.2 0.15 12.3 0.2 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EER29611.1 - 0.003 17.6 4.0 1.9 8.6 0.0 5.0 4 1 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat Inhibitor_I9 PF05922.16 EER29611.1 - 0.12 13.1 0.0 0.49 11.1 0.0 2.1 1 0 0 1 1 1 0 Peptidase inhibitor I9 DUF5486 PF17588.2 EER29611.1 - 0.19 11.6 2.2 0.63 10.0 1.4 2.3 2 0 0 2 2 1 0 Family of unknown function (DUF5486) TPR_6 PF13174.6 EER29611.1 - 0.24 12.1 18.7 8.6 7.2 0.0 7.6 9 0 0 9 9 7 0 Tetratricopeptide repeat TetR_C_15 PF17918.1 EER29611.1 - 0.48 11.2 4.3 2.3 9.0 3.8 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SHNi-TPR PF10516.9 EER29611.1 - 1.1 8.8 5.5 20 4.7 0.1 5.0 6 0 0 6 6 6 0 SHNi-TPR DUF982 PF06169.12 EER29611.1 - 1.7 8.7 5.5 45 4.2 0.1 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF982) Trypan_PARP PF05887.11 EER29611.1 - 4.9 7.1 21.1 2.1 8.3 17.0 2.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) C2 PF00168.30 EER29612.1 - 4.1e-76 251.9 0.2 1.9e-21 76.3 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EER29612.1 - 0.0001 21.8 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain adh_short PF00106.25 EER29613.1 - 4.6e-29 101.3 0.0 6.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER29613.1 - 6.9e-18 65.1 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER29613.1 - 0.0004 20.4 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.8 EER29613.1 - 0.14 11.9 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_1 PF00076.22 EER29614.1 - 4.7e-16 58.4 0.0 1.9e-12 46.8 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UDPGP PF01704.18 EER29615.1 - 4.8e-189 628.2 0.0 5.6e-189 628.0 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase zf-CCCH PF00642.24 EER29617.1 - 3e-08 33.4 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EER29617.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.4 3 0 0 3 3 3 1 Zinc finger domain RRM_1 PF00076.22 EER29617.1 - 0.0099 15.7 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EER29617.1 - 0.017 15.8 3.7 0.49 11.1 0.2 2.4 2 0 0 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 EER29617.1 - 2.2 8.5 8.3 0.41 10.9 1.3 2.4 2 2 0 2 2 2 0 Zinc-finger containing family DUF4185 PF13810.6 EER29618.1 - 0.027 13.7 0.3 0.041 13.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) Amidase PF01425.21 EER29619.1 - 2.5e-91 306.9 0.0 3.2e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 EER29620.1 - 1.2e-10 40.8 14.9 1.2e-10 40.8 14.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.21 EER29621.1 - 3.4e-07 30.0 0.0 5.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EER29621.1 - 0.00086 19.2 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EER29621.1 - 0.13 11.4 0.0 11 5.0 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein Fungal_trans PF04082.18 EER29622.1 - 1.8e-06 27.2 0.0 6.3e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29622.1 - 3.4e-05 23.9 12.6 5.9e-05 23.1 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYVE PF01363.21 EER29623.1 - 1.2e-20 73.4 2.6 1.2e-20 73.4 2.6 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EER29623.1 - 4.6e-07 30.1 5.3 4.6e-07 30.1 5.3 3.4 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EER29623.1 - 1.3e-05 24.9 4.1 1.3e-05 24.9 4.1 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EER29623.1 - 0.0041 17.4 5.7 0.0041 17.4 5.7 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EER29623.1 - 0.0061 16.3 5.7 0.0061 16.3 5.7 2.5 4 0 0 4 4 4 1 RING-like zinc finger FYVE_2 PF02318.16 EER29623.1 - 0.018 15.3 0.6 0.018 15.3 0.6 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger TRP PF06011.12 EER29624.1 - 1.9e-40 138.9 22.1 1.4e-33 116.3 20.2 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EER29624.1 - 9.2e-18 64.9 0.0 1.4e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF2678 PF10856.8 EER29624.1 - 2 8.4 5.9 66 3.5 5.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) RseC_MucC PF04246.12 EER29624.1 - 2.2 8.2 6.3 8.9 6.3 6.3 2.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Cys_Met_Meta_PP PF01053.20 EER29626.1 - 5.3e-63 212.8 0.0 1.3e-62 211.5 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EER29626.1 - 0.0003 20.1 0.0 0.00065 19.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EER29626.1 - 0.007 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GFA PF04828.14 EER29627.1 - 2e-23 82.5 1.3 2e-23 82.5 1.3 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme INPP5B_PH PF16776.5 EER29627.1 - 0.065 12.9 0.0 0.085 12.6 0.0 1.1 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Fungal_trans PF04082.18 EER29628.1 - 1.3e-11 44.0 0.0 2.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29628.1 - 1e-10 41.6 7.7 1.9e-10 40.7 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.24 EER29629.1 - 1.6e-30 106.1 30.7 2.4e-30 105.5 30.7 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EER29629.1 - 1.5e-25 90.3 0.2 2.3e-25 89.7 0.2 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EER29629.1 - 5.8e-06 26.3 0.4 0.14 11.9 0.1 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EER29629.1 - 2e-05 24.2 0.4 3.4e-05 23.4 0.4 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EER29629.1 - 4.6e-05 23.4 0.6 0.00013 22.0 0.1 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EER29629.1 - 5.8e-05 23.5 0.1 9.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 EER29629.1 - 0.00093 18.8 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_13 PF13166.6 EER29629.1 - 0.0012 17.6 0.2 0.014 14.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EER29629.1 - 0.0025 18.1 0.1 0.0076 16.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EER29629.1 - 0.003 17.1 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EER29629.1 - 0.0047 16.7 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EER29629.1 - 0.0062 16.7 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EER29629.1 - 0.009 15.7 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 EER29629.1 - 0.016 14.2 0.1 0.028 13.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC2_membrane_3 PF12698.7 EER29629.1 - 0.02 14.0 28.0 0.016 14.3 26.4 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_28 PF13521.6 EER29629.1 - 0.022 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EER29629.1 - 0.022 15.2 0.1 0.15 12.5 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EER29629.1 - 0.024 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EER29629.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EER29629.1 - 0.051 13.5 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 EER29629.1 - 0.054 13.6 0.8 1.1 9.3 0.2 2.4 1 1 1 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.12 EER29629.1 - 0.055 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EER29629.1 - 0.09 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EER29629.1 - 0.11 13.0 0.1 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EER29629.1 - 0.12 12.0 0.2 0.5 10.0 0.1 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 EER29629.1 - 0.15 12.0 0.1 0.5 10.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 EER29629.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EER29629.1 - 0.16 11.7 0.3 0.6 9.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain PIG-P PF08510.12 EER29629.1 - 1.8 8.5 13.6 0.033 14.1 1.7 2.5 2 0 0 2 2 2 0 PIG-P Mannosyl_trans3 PF11051.8 EER29630.1 - 1.3e-59 201.8 0.0 4.8e-36 124.5 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative DPPIV_N PF00930.21 EER29631.1 - 5e-114 380.7 1.4 6.7e-114 380.3 1.4 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EER29631.1 - 1.6e-40 138.9 1.5 2.7e-40 138.1 1.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.12 EER29631.1 - 0.0058 15.4 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 EER29631.1 - 0.0061 16.5 0.1 1.1 9.2 0.0 2.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Peptidase_S28 PF05577.12 EER29631.1 - 0.03 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 MAPEG PF01124.18 EER29632.1 - 4.8e-14 52.4 1.9 5.4e-14 52.2 1.9 1.1 1 0 0 1 1 1 1 MAPEG family MARVEL PF01284.23 EER29633.1 - 1.9e-06 28.0 11.2 4.4e-06 26.8 10.9 1.6 1 1 0 1 1 1 1 Membrane-associating domain CytB6-F_Fe-S PF08802.10 EER29633.1 - 0.064 13.3 0.5 0.064 13.3 0.5 2.2 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit ABC_cobalt PF09819.9 EER29633.1 - 4.9 7.3 11.4 3.1 8.0 7.9 2.4 2 1 0 2 2 2 0 ABC-type cobalt transport system, permease component Phospholip_A2_3 PF09056.11 EER29634.1 - 1.2e-43 148.2 6.9 1.4e-43 148.0 6.4 1.4 2 0 0 2 2 2 1 Prokaryotic phospholipase A2 Methyltransf_16 PF10294.9 EER29635.1 - 4e-11 43.0 0.0 3.6e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase HSP70 PF00012.20 EER29636.1 - 2.7e-264 878.0 17.5 3.1e-264 877.7 17.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EER29636.1 - 5.8e-15 54.9 6.3 3.8e-13 49.0 2.8 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EER29636.1 - 0.00059 19.6 0.1 0.0017 18.1 0.1 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain TetR_C_25 PF17933.1 EER29636.1 - 0.12 12.7 0.1 27 5.1 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain StbA PF06406.11 EER29636.1 - 0.13 11.5 6.8 0.064 12.5 0.3 2.7 2 1 1 3 3 3 0 StbA protein DUF4363 PF14276.6 EER29636.1 - 0.14 12.3 5.1 0.32 11.1 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Toxin-deaminase PF14424.6 EER29636.1 - 0.47 10.5 3.6 0.72 9.9 0.0 2.6 2 1 0 2 2 2 0 The BURPS668_1122 family of deaminases SMBP PF16785.5 EER29636.1 - 1.2 9.3 7.0 0.46 10.7 3.8 2.0 2 0 0 2 2 2 0 Small metal-binding protein FtsA PF14450.6 EER29636.1 - 1.8 9.0 13.7 0.86 10.1 0.6 4.2 3 3 0 3 3 3 0 Cell division protein FtsA DUF4570 PF15134.6 EER29636.1 - 4.7 7.3 11.2 1.4 9.0 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF2415 PF10313.9 EER29637.1 - 2e-15 56.4 0.0 4.2e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) DSHCT PF08148.12 EER29638.1 - 4e-52 176.2 0.5 1e-51 174.9 0.5 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EER29638.1 - 4.4e-37 126.9 0.0 8.9e-37 125.9 0.0 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 EER29638.1 - 8.2e-18 64.8 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 EER29638.1 - 6.5e-17 62.3 0.1 1.9e-16 60.8 0.1 1.8 1 1 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 EER29638.1 - 1.8e-06 28.3 0.0 7.6e-06 26.2 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER29638.1 - 1.8e-05 24.8 0.0 5.4e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GRP PF07172.11 EER29638.1 - 10 6.9 14.1 25 5.6 14.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family IBN_N PF03810.19 EER29639.1 - 1e-15 57.4 0.1 9e-13 47.9 0.0 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 EER29639.1 - 5.5e-07 28.7 0.0 1.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 EER29639.1 - 1.4e-06 28.4 0.6 0.00033 20.7 0.0 4.1 4 0 0 4 4 4 1 Exportin 1-like protein RTP1_C1 PF10363.9 EER29639.1 - 3.2e-05 24.1 0.9 0.43 10.8 0.1 3.4 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 EER29639.1 - 0.0082 15.9 0.5 0.71 9.6 0.1 3.6 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 EER29639.1 - 0.029 14.7 0.7 6.1 7.3 0.1 3.6 2 2 1 3 3 3 0 HEAT repeats CAS_CSE1 PF03378.15 EER29639.1 - 0.042 12.3 0.1 0.5 8.8 0.0 2.5 3 0 0 3 3 3 0 CAS/CSE protein, C-terminus HEAT_EZ PF13513.6 EER29639.1 - 0.079 13.5 7.6 12 6.5 0.4 5.5 5 1 1 6 6 6 0 HEAT-like repeat RRM_1 PF00076.22 EER29640.1 - 2.4e-08 33.7 0.1 8.2e-08 32.0 0.0 2.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EER29640.1 - 0.00027 20.9 0.0 0.00043 20.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MapZ_C2 PF18708.1 EER29640.1 - 0.001 19.3 0.1 0.0017 18.6 0.1 1.4 1 0 0 1 1 1 1 MapZ extracellular C-terminal domain 2 RRM_occluded PF16842.5 EER29640.1 - 0.042 13.7 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif AGOG PF09171.10 EER29640.1 - 0.057 12.7 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 N-glycosylase/DNA lyase DUF3391 PF11871.8 EER29640.1 - 0.19 12.3 0.0 0.19 12.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) ATG16 PF08614.11 EER29641.1 - 0.00033 20.9 1.0 0.00033 20.9 1.0 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF2046 PF09755.9 EER29641.1 - 0.014 14.6 0.5 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DivIC PF04977.15 EER29641.1 - 0.016 14.9 3.2 0.032 14.0 0.2 2.1 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 EER29641.1 - 0.024 15.3 4.3 3.5 8.3 0.4 2.4 2 0 0 2 2 2 0 SlyX FlaC_arch PF05377.11 EER29641.1 - 0.036 14.4 2.7 0.15 12.5 0.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 EER29641.1 - 0.072 13.5 2.0 0.42 11.0 0.3 2.0 2 0 0 2 2 2 0 Fez1 CENP-H PF05837.12 EER29641.1 - 1.7 9.1 5.2 0.81 10.1 0.9 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) PP2C_2 PF13672.6 EER29641.1 - 2 8.0 7.0 0.37 10.4 2.6 1.9 2 1 0 2 2 2 0 Protein phosphatase 2C Uso1_p115_C PF04871.13 EER29641.1 - 3.3 8.1 5.8 8.4 6.8 0.7 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF501 PF04417.12 EER29642.1 - 4.4 7.1 9.2 0.061 13.1 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF501) U1snRNP70_N PF12220.8 EER29642.1 - 4.6 7.9 15.2 1.3 9.7 3.4 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SURF6 PF04935.12 EER29642.1 - 5.5 6.7 26.5 0.17 11.7 11.0 2.5 2 0 0 2 2 2 0 Surfeit locus protein 6 Ferlin_C PF16165.5 EER29642.1 - 9.5 6.1 8.3 7 6.6 2.0 2.4 2 0 0 2 2 2 0 Ferlin C-terminus DbpA PF03880.15 EER29643.1 - 0.0059 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_1 PF00076.22 EER29643.1 - 0.088 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C PF12355.8 EER29644.1 - 0.079 13.9 0.3 0.11 13.5 0.3 1.2 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal MFS_1 PF07690.16 EER29645.1 - 1.8e-30 106.1 30.5 1.5e-28 99.8 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER29645.1 - 2.9e-09 36.3 7.7 2.9e-09 36.3 7.7 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter TarH PF02203.15 EER29645.1 - 0.25 11.3 0.0 9.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Tar ligand binding domain homologue MFS_1_like PF12832.7 EER29645.1 - 4.1 6.2 12.6 0.044 12.6 2.3 2.4 3 0 0 3 3 3 0 MFS_1 like family Fungal_TACC PF12709.7 EER29646.1 - 1.9e-10 41.1 24.0 7.7e-09 35.9 2.3 4.3 4 0 0 4 4 4 2 Fungal Transforming acidic coiled-coil (TACC) proteins QueH PF02677.14 EER29646.1 - 0.01 15.9 4.8 0.019 15.1 4.3 1.6 1 1 0 1 1 1 0 Epoxyqueuosine reductase QueH KIP1 PF07765.12 EER29646.1 - 7.5 6.8 10.4 3.6 7.8 2.9 3.0 2 1 0 2 2 2 0 KIP1-like protein FAD_binding_3 PF01494.19 EER29647.1 - 2.1e-10 40.4 0.0 6.2e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EER29647.1 - 0.0036 16.9 0.4 0.011 15.3 0.2 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EER29647.1 - 0.032 14.4 0.5 0.11 12.7 0.3 2.0 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EER29647.1 - 0.036 13.1 0.0 0.095 11.7 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase MIX PF18529.1 EER29647.1 - 0.039 13.7 0.0 0.6 9.8 0.0 2.4 3 0 0 3 3 3 0 Mitochondrial membrane-anchored proteins NAD_binding_9 PF13454.6 EER29647.1 - 0.11 12.5 0.0 0.74 9.8 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.18 EER29649.1 - 2.8e-29 102.0 1.7 4.3e-29 101.4 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29649.1 - 0.0018 18.4 17.0 0.0034 17.5 17.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S10 PF00450.22 EER29650.1 - 3.7e-99 333.0 0.2 4.3e-99 332.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 EER29651.1 - 2.8e-17 62.7 28.4 4.8e-17 61.9 28.4 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EER29651.1 - 1.4e-10 41.1 4.3 4.9e-10 39.3 4.3 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Amidohydro_1 PF01979.20 EER29652.1 - 1.3e-15 57.6 0.0 5.3e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EER29652.1 - 9.3e-10 38.6 1.8 2e-06 27.6 0.2 2.3 2 0 0 2 2 2 2 Amidohydrolase family GMC_oxred_N PF00732.19 EER29653.1 - 1.1e-49 169.4 0.0 1.4e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EER29653.1 - 4.1e-38 131.1 0.0 6.4e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EER29653.1 - 1e-05 24.8 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EER29653.1 - 0.001 18.3 0.1 0.18 10.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EER29653.1 - 0.0011 18.3 0.0 0.0023 17.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER29653.1 - 0.0013 18.9 0.1 0.0039 17.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EER29653.1 - 0.0085 15.7 0.1 0.022 14.3 0.1 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EER29653.1 - 0.0099 14.8 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.17 EER29653.1 - 0.087 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EER29653.1 - 0.099 12.0 0.1 1.1 8.5 0.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EER29653.1 - 0.13 12.8 0.1 2.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 EER29654.1 - 1.4e-158 528.2 0.0 1.7e-158 528.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 EER29654.1 - 0.087 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 WTAP/Mum2p family Glucosamine_iso PF01182.20 EER29655.1 - 9.2e-25 87.8 0.0 1.5e-24 87.2 0.0 1.3 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 EER29656.1 - 2.3e-71 240.8 0.0 3e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 EER29656.1 - 0.00059 20.1 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.22 EER29656.1 - 0.016 15.1 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain NDT80_PhoG PF05224.12 EER29657.1 - 3.7e-36 125.1 0.3 9.7e-36 123.7 0.0 1.9 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hexokinase_2 PF03727.16 EER29658.1 - 4e-55 186.9 0.0 6.5e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EER29658.1 - 1.6e-47 162.0 0.0 2.6e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Peptidase_S46 PF10459.9 EER29658.1 - 0.0041 15.8 0.0 0.0063 15.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase S46 p450 PF00067.22 EER29659.1 - 3e-59 201.0 0.0 3.9e-59 200.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EER29660.1 - 1.3e-14 54.3 0.0 2.6e-14 53.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER29660.1 - 4.9e-09 36.7 0.0 1e-08 35.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER29660.1 - 6.7e-08 33.1 0.0 1.8e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER29660.1 - 2.8e-06 27.2 0.0 1.3e-05 25.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER29660.1 - 7e-05 23.5 0.0 0.00024 21.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EER29660.1 - 0.00094 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 EER29660.1 - 0.0018 17.7 0.0 0.0051 16.2 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family COX14 PF14880.6 EER29661.1 - 4.1e-19 68.2 0.1 4.1e-19 68.2 0.1 2.7 3 0 0 3 3 3 1 Cytochrome oxidase c assembly GAD PF02938.14 EER29661.1 - 0.048 13.9 1.0 0.099 12.9 1.0 1.5 1 0 0 1 1 1 0 GAD domain Usp PF00582.26 EER29661.1 - 0.18 12.3 4.1 0.085 13.4 1.6 1.7 2 0 0 2 2 2 0 Universal stress protein family DUF2458 PF10454.9 EER29662.1 - 4.8e-69 231.4 0.3 7.4e-69 230.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DAHP_synth_1 PF00793.20 EER29663.1 - 1.1e-101 339.3 0.0 1.3e-101 339.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Thiolase_N PF00108.23 EER29665.1 - 7.8e-73 245.0 0.3 1.1e-72 244.5 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EER29665.1 - 1.1e-46 157.4 0.5 1.1e-46 157.4 0.5 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EER29665.1 - 0.028 14.0 3.0 0.1 12.1 1.7 2.3 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Polysacc_deac_2 PF04748.13 EER29665.1 - 0.036 13.2 0.0 0.072 12.3 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Ribosomal_L50 PF10501.9 EER29666.1 - 4.4e-20 71.9 0.0 7.7e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Rtf2 PF04641.12 EER29667.1 - 1.3e-66 224.7 2.8 1.6e-66 224.4 2.8 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EER29667.1 - 5.5e-08 32.5 0.9 0.0052 16.6 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EER29667.1 - 0.0014 18.6 0.1 0.0051 16.8 0.1 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EER29667.1 - 0.0089 16.0 0.7 0.025 14.5 0.7 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RVT PF13966.6 EER29667.1 - 0.14 12.9 0.5 0.99 10.2 0.0 2.3 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Fer4_6 PF12837.7 EER29667.1 - 0.2 11.8 0.8 0.59 10.3 0.8 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain Prok-RING_4 PF14447.6 EER29667.1 - 0.74 9.7 3.5 7.4 6.5 1.0 3.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 SRP-alpha_N PF04086.13 EER29667.1 - 6.9 6.5 8.8 13 5.6 8.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PRKCSH-like PF12999.7 EER29668.1 - 4e-48 163.5 6.5 3.3e-28 98.7 2.1 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EER29668.1 - 2.2e-31 108.6 0.3 2.2e-31 108.6 0.3 2.4 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EER29668.1 - 6.7e-08 33.4 0.2 6.7e-08 33.4 0.2 2.0 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 EER29668.1 - 0.013 15.3 2.1 0.013 15.3 2.1 1.7 2 0 0 2 2 2 0 Autophagy-related protein 27 OmpH PF03938.14 EER29668.1 - 0.3 11.4 9.9 0.55 10.6 8.6 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ax_dynein_light PF10211.9 EER29668.1 - 0.33 10.9 8.7 0.66 9.9 8.7 1.5 1 0 0 1 1 1 0 Axonemal dynein light chain Lebercilin PF15619.6 EER29668.1 - 0.46 10.1 20.2 0.77 9.4 16.0 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fzo_mitofusin PF04799.13 EER29668.1 - 0.48 10.0 7.6 0.1 12.2 2.4 2.3 3 0 0 3 3 3 0 fzo-like conserved region Mod_r PF07200.13 EER29668.1 - 0.53 10.4 11.0 0.44 10.7 0.4 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Macoilin PF09726.9 EER29668.1 - 0.98 7.9 8.7 1.6 7.2 8.7 1.3 1 0 0 1 1 1 0 Macoilin family Rab5-bind PF09311.11 EER29668.1 - 1 8.7 14.9 0.61 9.4 11.6 2.1 2 1 0 2 2 2 0 Rabaptin-like protein Fib_alpha PF08702.10 EER29668.1 - 1.2 9.3 7.5 4.8 7.4 4.7 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 EER29668.1 - 3.6 7.9 8.7 9.5 6.5 1.1 3.5 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 SlyX PF04102.12 EER29668.1 - 4.9 7.8 4.9 72 4.1 0.0 3.3 3 1 0 3 3 3 0 SlyX DUF4407 PF14362.6 EER29668.1 - 7.9 5.7 10.7 15 4.9 7.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PAP_assoc PF03828.19 EER29669.1 - 2.8e-13 49.9 0.9 6.2e-13 48.7 0.3 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EER29669.1 - 5.7e-11 42.6 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EER29669.1 - 0.16 12.0 0.0 0.5 10.5 0.0 1.8 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Mito_fiss_reg PF05308.11 EER29669.1 - 0.54 10.3 9.4 0.12 12.4 0.5 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Aldo_ket_red PF00248.21 EER29670.1 - 1.4e-63 214.8 0.0 1.8e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.14 EER29671.1 - 7.7e-05 23.0 0.1 7.7e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PG_binding_4 PF12229.8 EER29672.1 - 0.023 15.0 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative peptidoglycan binding domain PhyH PF05721.13 EER29674.1 - 2.2e-29 103.2 0.0 3.1e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Pex24p PF06398.11 EER29676.1 - 1.7e-98 330.0 0.7 2.2e-98 329.6 0.7 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Secretin_N PF03958.17 EER29676.1 - 0.011 16.1 0.3 0.027 14.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain Pam16 PF03656.13 EER29677.1 - 1.7e-35 121.8 0.8 1.8e-35 121.7 0.8 1.0 1 0 0 1 1 1 1 Pam16 MIOX PF05153.15 EER29678.1 - 1.4e-123 411.4 0.5 1.7e-123 411.0 0.5 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EER29678.1 - 0.021 15.0 0.2 0.34 11.1 0.2 2.5 1 1 0 1 1 1 0 HD domain UBD PF16455.5 EER29678.1 - 0.077 13.2 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-binding domain Aldo_ket_red PF00248.21 EER29679.1 - 1.1e-45 156.1 0.0 1.5e-43 149.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_1 PF01527.20 EER29679.1 - 0.17 12.3 0.0 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Transposase Stanniocalcin PF03298.13 EER29681.1 - 4.6e-05 22.8 0.6 6e-05 22.5 0.6 1.2 1 0 0 1 1 1 1 Stanniocalcin family Methyltransf_11 PF08241.12 EER29683.1 - 4.2e-12 46.5 0.0 1.2e-11 45.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER29683.1 - 1.2e-11 45.1 0.0 2.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EER29683.1 - 3e-11 43.4 0.0 4.2e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER29683.1 - 2.9e-10 40.1 0.0 3.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EER29683.1 - 2.6e-07 30.5 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_12 PF08242.12 EER29683.1 - 8e-07 29.7 0.0 1.3e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EER29683.1 - 7e-05 22.4 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_16 PF10294.9 EER29683.1 - 0.0019 17.9 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Ubie_methyltran PF01209.18 EER29683.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Pox_MCEL PF03291.16 EER29683.1 - 0.012 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme MTS PF05175.14 EER29683.1 - 0.045 13.3 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FAT PF02259.23 EER29685.1 - 1.8e-135 451.6 10.3 5.6e-135 450.0 10.3 1.9 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EER29685.1 - 1e-70 238.4 0.1 2e-70 237.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EER29685.1 - 1.1e-68 230.2 11.2 1.2e-61 207.3 1.2 5.4 5 1 1 6 6 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EER29685.1 - 2.1e-40 137.1 3.6 7.7e-40 135.3 0.1 3.8 4 0 0 4 4 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 EER29685.1 - 3.6e-15 54.8 25.9 6.5e-05 22.9 0.0 13.6 14 0 0 14 14 13 2 HEAT repeat FATC PF02260.20 EER29685.1 - 1.8e-14 53.3 0.3 4.5e-14 52.0 0.3 1.8 1 0 0 1 1 1 1 FATC domain HEAT_EZ PF13513.6 EER29685.1 - 1.8e-14 53.8 17.1 0.0015 19.0 0.0 11.3 10 1 1 11 11 10 4 HEAT-like repeat HEAT_2 PF13646.6 EER29685.1 - 3.9e-14 52.8 21.4 0.0012 19.2 0.0 8.6 9 2 1 10 10 7 4 HEAT repeats UME PF08064.13 EER29685.1 - 1.7e-06 27.9 6.9 1.7 8.6 0.2 7.2 6 1 0 6 6 6 2 UME (NUC010) domain Cnd1 PF12717.7 EER29685.1 - 3.3e-06 27.2 0.1 1.6 8.7 0.0 5.7 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EER29685.1 - 3e-05 22.8 7.4 0.016 13.8 0.2 4.9 3 2 1 4 4 4 2 Adaptin N terminal region Tti2 PF10521.9 EER29685.1 - 5.6e-05 22.8 3.2 1.2 8.6 0.0 5.3 3 1 1 5 5 5 2 Tti2 family CLASP_N PF12348.8 EER29685.1 - 0.00064 19.3 4.1 3.4 7.2 0.0 5.7 5 2 1 6 6 6 1 CLASP N terminal IFRD PF05004.13 EER29685.1 - 0.0015 17.7 2.9 3.4 6.7 0.0 4.7 4 2 0 4 4 4 2 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 EER29685.1 - 0.0016 19.0 7.5 40 4.9 0.0 8.1 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region Spore_III_AB PF09548.10 EER29685.1 - 0.0079 16.3 0.5 0.34 11.0 0.0 3.9 4 0 0 4 4 4 1 Stage III sporulation protein AB (spore_III_AB) TPR_14 PF13428.6 EER29685.1 - 0.0098 16.6 10.2 10 7.3 0.2 6.0 4 1 1 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EER29685.1 - 0.027 14.7 3.5 63 3.9 0.0 4.9 4 0 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Dopey_N PF04118.14 EER29685.1 - 0.08 12.0 2.9 2.1 7.4 0.9 3.4 2 1 1 3 3 3 0 Dopey, N-terminal TPR_2 PF07719.17 EER29685.1 - 0.11 12.7 3.4 63 4.0 0.2 4.6 3 0 0 3 3 3 0 Tetratricopeptide repeat U3snoRNP10 PF12397.8 EER29685.1 - 0.17 12.2 0.5 24 5.3 0.0 4.1 4 0 0 4 4 3 0 U3 small nucleolar RNA-associated protein 10 DUF4200 PF13863.6 EER29685.1 - 0.25 11.8 1.1 0.72 10.3 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TPR_7 PF13176.6 EER29685.1 - 0.76 9.9 4.9 83 3.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Sec7_N PF12783.7 EER29685.1 - 0.91 9.4 3.8 15 5.4 0.0 4.5 5 1 0 5 5 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_19 PF14559.6 EER29685.1 - 7.2 7.2 10.2 15 6.2 0.0 5.8 7 0 0 7 7 5 0 Tetratricopeptide repeat Mit_ribos_Mrp51 PF11709.8 EER29686.1 - 6.5e-120 401.1 0.3 7.4e-120 400.9 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit SHOCT PF09851.9 EER29686.1 - 5.9 6.8 5.9 1 9.2 0.2 2.6 3 0 0 3 3 3 0 Short C-terminal domain Ribosomal_S17e PF00833.18 EER29687.1 - 1.2e-60 202.8 0.8 1.5e-60 202.5 0.8 1.1 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 EER29688.1 - 1.4e-23 83.0 0.0 2.2e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_1 PF00018.28 EER29689.1 - 1.6e-09 37.2 0.2 4.1e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EER29689.1 - 6.6e-09 35.5 0.2 1.7e-08 34.2 0.2 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EER29689.1 - 4.6e-08 32.6 0.0 9.7e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Adaptin_N PF01602.20 EER29690.1 - 6.5e-118 394.5 4.9 8.1e-118 394.2 4.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EER29690.1 - 3.1e-56 189.9 8.0 1.2e-55 188.0 0.2 3.6 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EER29690.1 - 2.2e-13 50.4 6.6 8.1e-08 32.6 0.2 5.0 4 1 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EER29690.1 - 1.7e-10 40.2 5.6 0.042 14.1 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 EER29690.1 - 5.8e-05 23.5 7.9 5.5 7.6 0.1 6.1 7 0 0 7 7 6 2 HEAT-like repeat Arm PF00514.23 EER29690.1 - 0.0028 17.6 4.8 2.1 8.5 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat TIP120 PF08623.10 EER29690.1 - 0.009 15.8 2.6 1.1 9.0 0.1 3.5 3 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 EER29690.1 - 0.028 14.0 0.6 8.4 5.9 0.0 3.3 3 1 0 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.7 EER29690.1 - 0.063 13.9 1.0 2.2 8.9 0.0 3.4 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EER29690.1 - 0.08 13.1 1.0 2 8.6 0.1 3.4 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 EER29690.1 - 0.096 12.6 1.4 0.37 10.7 1.5 2.1 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1077 PF06417.12 EER29691.1 - 6.9e-43 145.4 5.9 8.8e-43 145.1 5.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) DUF4219 PF13961.6 EER29691.1 - 0.081 12.6 1.5 1.3 8.8 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) Aminotran_5 PF00266.19 EER29692.1 - 5.9e-08 32.1 0.0 2.5e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EER29692.1 - 0.17 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lactamase_B PF00753.27 EER29693.1 - 1.7e-06 28.2 0.4 5.3e-05 23.3 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EER29693.1 - 0.002 17.6 0.0 0.0042 16.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Hemerythrin PF01814.23 EER29694.1 - 8.9e-09 36.1 0.4 1.3e-08 35.5 0.4 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fe-S_biosyn PF01521.20 EER29695.1 - 5e-09 36.3 0.1 0.00051 20.2 0.0 2.6 2 1 1 3 3 3 2 Iron-sulphur cluster biosynthesis Paf67 PF10255.9 EER29696.1 - 4.6e-156 519.9 0.0 5.4e-156 519.6 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EER29696.1 - 0.0078 16.2 0.1 0.12 12.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 EER29696.1 - 0.068 12.1 0.2 0.094 11.7 0.2 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit RRM_occluded PF16842.5 EER29697.1 - 0.00019 21.3 0.1 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif CDH-cyt PF16010.5 EER29698.1 - 5.4e-27 94.7 0.0 8.2e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 EER29698.1 - 0.00095 19.4 0.1 0.0046 17.2 0.0 2.0 2 0 0 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.16 EER29698.1 - 0.0014 18.8 5.6 0.0035 17.5 5.6 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PDH PF02153.17 EER29699.1 - 1.7e-14 53.5 0.0 2.5e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 EER29699.1 - 3.4e-05 24.3 0.0 7.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EER29699.1 - 4.6e-05 23.7 0.0 8.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EER29699.1 - 0.002 17.8 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EER29699.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EER29699.1 - 0.02 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EER29699.1 - 0.041 14.1 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_S11 PF00411.19 EER29700.1 - 2.1e-46 156.8 1.1 2.6e-46 156.5 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EER29700.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) AAR2 PF05282.11 EER29701.1 - 2.5e-100 336.3 0.0 3e-100 336.1 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S9 PF00380.19 EER29702.1 - 1.9e-34 118.8 0.2 2.1e-34 118.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.18 EER29703.1 - 7.6e-42 142.5 0.0 9.4e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.18 EER29704.1 - 2.3e-79 264.1 0.4 1e-42 145.5 0.6 2.1 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.6 EER29705.1 - 1.1e-126 422.8 0.0 2.6e-126 421.6 0.0 1.7 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 EER29705.1 - 4.6e-35 120.3 0.2 6.4e-33 113.4 0.0 3.5 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 EER29705.1 - 1e-34 118.4 0.9 1.6e-32 111.4 0.3 4.2 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EER29705.1 - 1.2e-24 86.3 2.4 1.7e-23 82.7 0.2 3.9 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EER29705.1 - 4.8e-16 58.6 10.4 1.1e-15 57.4 10.4 1.7 1 0 0 1 1 1 1 Hr1 repeat Proteasom_PSMB PF10508.9 EER29705.1 - 4e-05 22.3 0.2 0.2 10.1 0.2 3.4 3 1 0 3 3 3 2 Proteasome non-ATPase 26S subunit Uds1 PF15456.6 EER29705.1 - 0.083 13.1 6.2 0.19 11.9 6.2 1.5 1 0 0 1 1 1 0 Up-regulated During Septation DLP_helical PF18709.1 EER29705.1 - 0.35 10.0 2.8 0.6 9.3 2.8 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain PsiA PF06952.11 EER29705.1 - 0.4 9.9 2.5 3.9 6.7 0.0 2.3 2 0 0 2 2 2 0 PsiA protein LON_substr_bdg PF02190.16 EER29706.1 - 1.5e-23 83.8 0.0 2.6e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EER29706.1 - 1.1e-11 44.4 24.7 2.7e-09 36.7 14.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EER29706.1 - 7.7e-09 35.3 20.9 6e-08 32.4 9.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EER29706.1 - 8.4e-09 35.4 24.2 0.00023 21.2 12.3 2.8 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EER29706.1 - 9.4e-08 31.8 23.9 3e-07 30.2 13.5 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER29706.1 - 1.1e-07 32.0 23.7 5e-07 30.0 13.4 2.6 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 EER29706.1 - 1.3e-05 25.1 25.8 2.3e-05 24.3 8.3 3.3 3 0 0 3 3 3 2 RING-type zinc-finger Prok-RING_4 PF14447.6 EER29706.1 - 6.5e-05 22.7 22.2 0.00031 20.5 11.9 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 U-box PF04564.15 EER29706.1 - 9.4e-05 22.5 0.1 0.0015 18.7 0.0 2.5 2 0 0 2 2 2 1 U-box domain zf-RING_5 PF14634.6 EER29706.1 - 9.8e-05 22.2 22.8 0.0002 21.3 11.2 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_10 PF16685.5 EER29706.1 - 0.00036 20.6 20.2 0.0043 17.2 7.5 2.5 2 0 0 2 2 2 2 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EER29706.1 - 0.0013 18.4 8.5 0.0013 18.4 8.5 2.2 3 0 0 3 3 2 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.11 EER29706.1 - 0.02 14.8 1.3 0.051 13.5 1.3 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.7 EER29706.1 - 0.6 10.4 13.6 0.34 11.2 9.8 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain Paf1 PF03985.13 EER29707.1 - 6.1e-54 183.6 0.0 8.9e-54 183.1 0.0 1.2 1 0 0 1 1 1 1 Paf1 NMT1_3 PF16868.5 EER29707.1 - 0.21 11.0 0.1 0.32 10.4 0.1 1.2 1 0 0 1 1 1 0 NMT1-like family Actin PF00022.19 EER29708.1 - 6.7e-30 104.0 0.0 9e-17 60.8 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EER29708.1 - 0.0001 21.3 0.0 0.071 11.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 EER29708.1 - 0.00043 19.6 0.1 0.041 13.1 0.1 2.2 2 0 0 2 2 2 2 Putative actin-like family FtsA PF14450.6 EER29708.1 - 0.00085 19.7 0.0 0.014 15.8 0.0 2.6 2 1 0 2 2 2 1 Cell division protein FtsA DUF2114 PF09887.9 EER29708.1 - 0.11 11.0 0.2 0.15 10.5 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Arf PF00025.21 EER29709.1 - 1.3e-72 242.9 0.0 1.5e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EER29709.1 - 7.4e-14 52.0 0.0 9.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EER29709.1 - 3.7e-11 42.8 0.0 4.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EER29709.1 - 4.5e-10 39.4 0.0 5.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EER29709.1 - 1.3e-09 37.7 0.2 1.4e-05 24.4 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EER29709.1 - 2.4e-08 33.6 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EER29709.1 - 5e-06 26.6 0.0 8.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EER29709.1 - 0.0029 17.2 0.0 0.24 10.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EER29709.1 - 0.0031 16.5 0.1 0.0071 15.4 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 EER29709.1 - 0.0087 15.6 0.4 0.039 13.5 0.4 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Catalase PF00199.19 EER29710.1 - 1.3e-196 653.3 0.2 1.6e-196 652.9 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EER29710.1 - 4e-11 42.9 0.0 1.1e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive MBOAT_2 PF13813.6 EER29711.1 - 3.2e-23 81.8 0.6 3.2e-23 81.8 0.6 2.9 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family Rer1 PF03248.13 EER29712.1 - 4e-79 264.3 2.7 4.7e-79 264.1 2.7 1.0 1 0 0 1 1 1 1 Rer1 family ECH_1 PF00378.20 EER29713.1 - 3.4e-76 255.9 0.0 3.9e-76 255.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER29713.1 - 5.3e-35 121.5 0.2 5e-34 118.3 0.2 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase A_deaminase PF00962.22 EER29715.1 - 1.2e-22 80.7 0.0 1.4e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Acetyltransf_10 PF13673.7 EER29716.1 - 1.4e-08 34.7 0.0 5.8e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EER29716.1 - 4.5e-07 30.1 0.0 1e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER29716.1 - 7.8e-07 29.4 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EER29716.1 - 0.00074 19.6 0.0 0.0043 17.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EER29716.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein DUF3419 PF11899.8 EER29717.1 - 2.7e-155 517.3 0.0 3.5e-155 516.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 EER29717.1 - 0.00021 21.9 0.0 0.00092 19.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER29717.1 - 0.00087 19.1 0.0 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER29717.1 - 0.092 13.4 0.0 0.38 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EER29717.1 - 0.12 13.2 0.0 0.57 11.0 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain FMN_red PF03358.15 EER29718.1 - 9.2e-24 83.9 0.0 1.3e-23 83.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EER29718.1 - 5e-07 29.6 0.0 6.5e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Lipase_3 PF01764.25 EER29719.1 - 8.4e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EER29719.1 - 0.17 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 VPS9 PF02204.18 EER29720.1 - 1e-24 86.7 0.0 3.7e-24 84.9 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Sel1 PF08238.12 EER29721.1 - 6.4e-14 52.1 7.6 0.00031 21.3 0.1 4.2 4 0 0 4 4 4 3 Sel1 repeat Mt_ATP-synt_B PF05405.14 EER29722.1 - 6.3e-49 165.7 11.4 7.8e-49 165.4 11.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) rve_3 PF13683.6 EER29722.1 - 0.054 13.3 1.1 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Integrase core domain V_ATPase_I PF01496.19 EER29722.1 - 0.42 8.5 5.9 0.55 8.1 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CBF PF03914.17 EER29723.1 - 2.8e-37 128.4 1.9 9.5e-37 126.6 0.3 2.5 3 0 0 3 3 3 1 CBF/Mak21 family DUF4806 PF16064.5 EER29723.1 - 0.14 12.5 0.2 1.4 9.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4806) GPI-anchored PF10342.9 EER29725.1 - 2.1e-19 70.1 0.4 2.1e-19 70.1 0.4 2.2 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SHE3 PF17078.5 EER29726.1 - 3e-08 33.6 27.5 9.9e-07 28.7 22.2 2.1 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 EER29726.1 - 0.00099 19.4 31.3 0.0012 19.1 15.2 2.4 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) T3SS_basalb_I PF17001.5 EER29726.1 - 0.85 10.3 7.3 13 6.5 2.0 3.3 2 1 1 3 3 3 0 Type III secretion basal body protein I, YscI, HrpB, PscI KASH_CCD PF14662.6 EER29726.1 - 2.2 8.1 31.3 3.7 7.3 7.3 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF1729 PF08354.10 EER29726.1 - 8.5 5.2 9.0 1.6 7.5 5.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1729) LGFP PF08310.11 EER29727.1 - 0.08 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 LGFP repeat MMS19_C PF12460.8 EER29728.1 - 1.4e-109 367.1 11.2 1.4e-106 357.1 5.5 3.5 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EER29728.1 - 1.4e-89 300.1 2.2 1.5e-88 296.8 0.2 3.0 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EER29728.1 - 1.5e-06 28.5 6.9 0.24 11.9 0.0 6.3 5 0 0 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.6 EER29728.1 - 0.015 15.7 3.4 56 4.2 0.0 6.2 7 0 0 7 7 7 0 HEAT repeats EH_Signature PF15611.6 EER29728.1 - 0.022 14.2 1.6 5.5 6.3 0.0 2.4 1 1 1 2 2 2 0 EH_Signature domain HEAT PF02985.22 EER29728.1 - 0.045 14.0 9.5 14 6.3 0.0 7.2 8 0 0 8 8 8 0 HEAT repeat Fasciclin PF02469.22 EER29729.1 - 0.0014 18.9 0.0 0.0034 17.6 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain EMC3_TMCO1 PF01956.16 EER29730.1 - 9.2e-45 152.4 0.0 1.3e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like SPC25 PF06703.11 EER29731.1 - 8.9e-49 165.4 0.0 1e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH PF00763.23 EER29732.1 - 1.5e-24 86.5 0.0 2.3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EER29732.1 - 8.2e-12 44.7 0.0 1.1e-08 34.5 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CdiI_N PF18228.1 EER29732.1 - 0.035 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 CdiI N-terminal domain LTD PF00932.19 EER29732.1 - 0.046 14.1 0.0 0.13 12.7 0.0 1.7 2 0 0 2 2 2 0 Lamin Tail Domain ATP-synt_ab PF00006.25 EER29733.1 - 9.6e-73 244.3 0.0 1.4e-72 243.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EER29733.1 - 2.6e-48 163.5 1.4 4.6e-48 162.7 1.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EER29733.1 - 9.5e-15 54.9 3.2 2.4e-14 53.6 3.2 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF962 PF06127.11 EER29734.1 - 7.9e-20 70.7 4.3 2.4e-19 69.2 4.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF962) SHS2_Rpb7-N PF03876.17 EER29735.1 - 1.1e-14 54.5 0.1 1.8e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EER29735.1 - 1.4e-11 44.5 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 EER29735.1 - 0.023 14.9 0.0 0.044 14.0 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 RRM_1 PF00076.22 EER29736.1 - 5.1e-36 122.3 0.1 2.2e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EER29736.1 - 0.19 11.6 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif TPP_enzyme_N PF02776.18 EER29737.1 - 1.7e-45 154.7 0.1 4.3e-45 153.4 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EER29737.1 - 7.9e-34 116.3 0.0 1.5e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EER29737.1 - 8.7e-18 64.6 0.1 3e-17 62.8 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 EER29737.1 - 0.13 12.3 0.2 0.41 10.7 0.2 1.8 1 0 0 1 1 1 0 B12 binding domain CO_dh PF02552.16 EER29737.1 - 0.21 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Fungal_trans PF04082.18 EER29738.1 - 4.3e-11 42.3 0.1 1.1e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29738.1 - 2e-07 31.0 10.5 3.8e-07 30.1 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.12 EER29738.1 - 0.035 14.0 0.1 0.087 12.7 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 HEAT_2 PF13646.6 EER29739.1 - 0.12 12.7 0.2 1.8 9.0 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats LSM PF01423.22 EER29740.1 - 1.2e-15 56.9 0.2 1.4e-15 56.7 0.2 1.0 1 0 0 1 1 1 1 LSM domain PALP PF00291.25 EER29741.1 - 1.7e-59 201.6 0.3 4e-59 200.4 0.3 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.9 EER29742.1 - 3.2e-18 65.2 0.2 6.3e-18 64.3 0.2 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.6 EER29742.1 - 0.099 12.9 0.1 4.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain TPR_1 PF00515.28 EER29743.1 - 9.8e-27 91.6 1.7 1.7e-08 33.9 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EER29743.1 - 1.8e-24 83.9 1.2 9.7e-07 28.4 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EER29743.1 - 9.1e-21 73.3 1.2 4.3e-08 32.7 0.0 5.0 4 2 1 5 5 5 3 TPR repeat TPR_14 PF13428.6 EER29743.1 - 8.2e-17 60.5 3.9 9e-05 23.0 0.0 5.1 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER29743.1 - 3e-16 58.2 0.9 1.7e-06 27.8 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EER29743.1 - 4.8e-16 59.1 10.8 1.6e-05 25.4 0.1 4.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EER29743.1 - 2.2e-15 55.9 0.4 0.033 14.6 0.0 4.9 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 EER29743.1 - 1.6e-14 54.1 3.6 0.00072 20.0 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EER29743.1 - 1.2e-12 47.9 2.1 1.7e-06 28.2 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EER29743.1 - 9.9e-11 40.9 1.4 0.0041 17.1 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 EER29743.1 - 6.7e-10 39.2 0.2 0.015 15.6 0.0 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EER29743.1 - 6.2e-09 35.9 4.1 0.0099 16.0 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EER29743.1 - 1.5e-06 28.4 1.6 2.3 9.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EER29743.1 - 1.7e-05 25.0 2.1 0.0056 16.9 0.4 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EER29743.1 - 6.6e-05 22.3 0.8 0.13 11.4 0.2 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.12 EER29743.1 - 7.1e-05 22.7 0.0 1.6 8.8 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EER29743.1 - 0.001 18.9 4.5 0.03 14.2 0.3 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EER29743.1 - 0.0092 16.0 3.2 9.5 6.4 0.1 4.7 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain DUF1641 PF07849.11 EER29743.1 - 0.099 12.5 0.2 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) BTAD PF03704.17 EER29743.1 - 1.2 9.6 6.1 10 6.5 0.1 3.1 4 0 0 4 4 2 0 Bacterial transcriptional activator domain CDP-OH_P_transf PF01066.21 EER29744.1 - 2.7e-14 53.7 0.1 2.7e-14 53.7 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Mo-co_dimer PF03404.16 EER29745.1 - 0.2 11.7 0.1 0.31 11.0 0.1 1.2 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Zn_clus PF00172.18 EER29746.1 - 6.9e-06 26.1 10.6 6.9e-06 26.1 10.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EER29746.1 - 0.0014 17.5 1.3 0.007 15.2 1.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3357 PF11837.8 EER29746.1 - 0.034 14.6 0.1 16 6.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) ADH_N PF08240.12 EER29747.1 - 4.2e-25 87.8 0.2 7.7e-25 86.9 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER29747.1 - 1e-20 74.0 0.9 1.5e-20 73.5 0.9 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER29747.1 - 6.6e-06 27.2 0.0 1.1e-05 26.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EER29747.1 - 0.034 13.4 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELO PF01151.18 EER29748.1 - 1.5e-83 280.2 1.9 2e-83 279.8 1.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Per1 PF04080.13 EER29749.1 - 0.02 14.6 0.5 0.023 14.5 0.5 1.0 1 0 0 1 1 1 0 Per1-like family APH PF01636.23 EER29750.1 - 3.7e-08 33.6 0.0 7.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EER29750.1 - 0.063 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.11 EER29750.1 - 0.081 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) CHAP PF05257.16 EER29752.1 - 0.021 15.4 0.7 0.069 13.7 0.6 1.9 2 0 0 2 2 2 0 CHAP domain AIM3 PF17096.5 EER29753.1 - 0.01 16.8 1.1 0.01 16.8 1.1 6.9 4 3 3 7 7 7 1 Altered inheritance of mitochondria protein 3 Hexapep PF00132.24 EER29754.1 - 4.8e-07 29.2 5.7 0.0055 16.4 0.6 2.9 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EER29754.1 - 0.0001 21.4 2.7 0.017 14.1 0.1 2.1 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 EER29754.1 - 0.0036 17.7 0.0 0.0059 17.0 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EER29754.1 - 0.0091 15.6 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 EER29754.1 - 0.013 13.7 0.3 0.025 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Spt20 PF12090.8 EER29756.1 - 1.5e-57 194.9 3.4 1.5e-57 194.9 3.4 5.3 3 1 1 4 4 4 1 Spt20 family TruD PF01142.18 EER29757.1 - 2.7e-62 210.9 0.0 6.6e-58 196.5 0.0 3.5 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) RPE65 PF03055.15 EER29758.1 - 5.1e-112 375.4 0.0 5.7e-112 375.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2293 PF10056.9 EER29759.1 - 1.7e-29 101.9 0.3 3.6e-29 100.8 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2293) ketoacyl-synt PF00109.26 EER29760.1 - 1.5e-60 205.0 0.0 2.4e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EER29760.1 - 1.5e-58 197.6 0.0 8.1e-58 195.3 0.0 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EER29760.1 - 5.5e-55 186.7 0.0 9.9e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EER29760.1 - 1.6e-43 149.5 0.1 2.6e-43 148.7 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EER29760.1 - 1.5e-35 121.8 0.0 3.2e-35 120.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EER29760.1 - 1.7e-19 70.4 0.0 5.9e-19 68.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EER29760.1 - 1.2e-17 64.1 0.2 3.7e-17 62.5 0.2 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EER29760.1 - 2.8e-17 63.2 0.0 9.1e-12 45.4 0.0 2.8 2 0 0 2 2 2 2 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EER29760.1 - 1.7e-14 54.0 0.0 4e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EER29760.1 - 7.3e-14 51.7 1.9 1.9e-12 47.1 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_31 PF13847.6 EER29760.1 - 4e-13 49.4 0.0 5.3e-12 45.8 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EER29760.1 - 3.7e-12 47.5 0.0 5.7e-11 43.6 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EER29760.1 - 3e-11 43.9 0.0 3.8e-10 40.3 0.0 3.0 4 0 0 4 4 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER29760.1 - 1.1e-09 38.8 0.0 4.3e-09 36.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EER29760.1 - 4.9e-08 32.8 0.0 1.4e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EER29760.1 - 1.1e-07 31.5 0.1 2.5e-07 30.3 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EER29760.1 - 1.7e-06 28.3 0.1 4.6e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EER29760.1 - 5.4e-06 26.2 0.1 1.7e-05 24.6 0.1 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.18 EER29760.1 - 0.00015 21.2 0.0 0.00042 19.7 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.10 EER29760.1 - 0.00086 19.1 0.1 0.0032 17.3 0.2 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PHD PF00628.29 EER29761.1 - 2.3e-08 33.8 7.6 3.8e-08 33.1 7.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EER29761.1 - 0.89 9.2 5.8 1.6 8.4 5.8 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_M35 PF02102.15 EER29762.1 - 1.8e-97 326.5 0.7 2.2e-97 326.2 0.7 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EER29762.1 - 1.3e-42 145.8 1.1 1.9e-42 145.2 1.1 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 EER29762.1 - 0.0005 19.7 2.0 0.093 12.3 0.3 2.1 2 0 0 2 2 2 2 Putative peptidase family Coagulin PF02035.15 EER29762.1 - 0.061 13.2 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Coagulin Pkinase PF00069.25 EER29763.1 - 9.6e-39 133.3 0.0 1.3e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29763.1 - 2.3e-20 73.0 0.0 3.1e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EER29763.1 - 4e-05 23.1 0.0 0.0042 16.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EER29763.1 - 0.00076 18.4 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FHA PF00498.26 EER29763.1 - 0.06 13.7 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 FHA domain Kdo PF06293.14 EER29763.1 - 0.14 11.5 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EER29763.1 - 0.21 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Mtc PF03820.17 EER29764.1 - 3.5e-118 394.2 0.0 3.9e-118 394.0 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.25 EER29765.1 - 3.7e-48 164.2 0.0 1.5e-47 162.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29765.1 - 5.4e-19 68.5 0.0 1.6e-18 67.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5498 PF17602.2 EER29765.1 - 0.046 14.2 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5498) TAF4 PF05236.14 EER29766.1 - 5.4e-31 108.4 0.4 1.2e-29 103.9 0.4 2.6 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 EER29767.1 - 9.4e-82 273.8 0.0 1.4e-81 273.2 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EER29767.1 - 2.6e-30 104.9 0.0 1e-29 103.0 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.27 EER29767.1 - 8.8e-22 78.1 0.1 1.6e-21 77.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EER29767.1 - 3.6e-16 59.2 0.1 6.3e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EER29767.1 - 3e-12 46.3 0.1 5.8e-12 45.4 0.1 1.4 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EER29767.1 - 5.1e-05 22.9 0.1 0.00014 21.4 0.1 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EER29767.1 - 0.0001 22.2 0.0 0.00031 20.7 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain IL15 PF02372.15 EER29767.1 - 0.19 11.7 0.1 0.68 9.9 0.1 1.9 1 0 0 1 1 1 0 Interleukin 15 Sugar_tr PF00083.24 EER29768.1 - 1.1e-79 268.4 20.6 1.3e-79 268.2 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EER29768.1 - 1.7e-30 106.1 53.7 2e-26 92.8 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EER29768.1 - 3.6e-06 25.8 21.7 6.3e-05 21.7 5.0 3.2 2 1 0 3 3 3 3 MFS/sugar transport protein Jas PF16135.5 EER29768.1 - 0.0063 16.7 0.3 1.5 9.0 0.0 2.5 2 0 0 2 2 2 2 TPL-binding domain in jasmonate signalling AA_permease_C PF13906.6 EER29768.1 - 0.05 13.7 0.9 0.22 11.6 0.9 2.1 1 0 0 1 1 1 0 C-terminus of AA_permease TRI12 PF06609.13 EER29768.1 - 0.063 11.7 12.9 0.0085 14.6 3.0 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Aminotran_3 PF00202.21 EER29769.1 - 5.2e-89 298.7 0.0 6.4e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FYVE PF01363.21 EER29770.1 - 4.4e-14 52.4 7.8 7e-14 51.7 7.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EER29770.1 - 0.18 12.0 13.4 0.2 11.9 9.1 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger BTB_2 PF02214.22 EER29771.1 - 4.7e-10 39.7 0.1 1.6e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 EER29771.1 - 0.0018 18.4 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain GST_N PF02798.20 EER29772.1 - 4e-09 36.7 0.0 6.5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EER29772.1 - 1.1e-08 35.2 0.0 2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EER29772.1 - 1.7e-07 31.3 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EER29772.1 - 4.4e-06 26.9 0.0 9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EER29772.1 - 5.6e-06 26.7 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EER29772.1 - 6.4e-06 26.1 0.0 1.5e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.12 EER29773.1 - 4.8e-05 23.3 0.1 5.3e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) COX7a PF02238.15 EER29773.1 - 0.068 13.6 0.7 0.1 13.0 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII Rotamase_2 PF13145.6 EER29773.1 - 0.23 12.3 0.2 0.31 11.9 0.2 1.1 1 0 0 1 1 1 0 PPIC-type PPIASE domain SAP18 PF06487.12 EER29774.1 - 5e-52 175.8 0.0 6e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Pyr_redox_3 PF13738.6 EER29775.1 - 1.4e-06 27.8 0.0 3e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER29775.1 - 0.028 13.6 0.0 0.58 9.2 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Arf PF00025.21 EER29776.1 - 1.1e-38 132.4 0.1 7.4e-26 90.7 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EER29776.1 - 7.4e-13 48.4 0.0 1.8e-06 27.3 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EER29776.1 - 1.5e-10 41.3 0.0 4.3e-10 39.9 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EER29776.1 - 1.3e-06 28.1 0.0 0.0011 18.6 0.0 2.6 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.23 EER29776.1 - 1.7e-06 28.1 0.0 6.8e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EER29776.1 - 2.9e-06 26.8 0.0 5e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EER29776.1 - 3.8e-06 26.4 0.0 2.3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EER29776.1 - 0.0022 17.6 0.0 0.06 12.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EER29776.1 - 0.063 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 EER29776.1 - 0.091 12.3 0.2 0.22 11.0 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EER29776.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PIGA PF08288.12 EER29777.1 - 2.8e-46 156.0 4.7 3.1e-46 155.9 2.3 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EER29777.1 - 5.7e-29 101.3 0.6 9.7e-29 100.5 0.6 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EER29777.1 - 2.5e-27 95.5 0.0 3.8e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EER29777.1 - 8.7e-25 87.7 0.1 1.6e-24 86.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EER29777.1 - 6e-14 52.8 0.0 1.2e-13 51.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EER29777.1 - 5.7e-06 26.4 0.1 1.2e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EER29777.1 - 0.0007 19.9 0.0 0.002 18.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.29 EER29778.1 - 4.2e-36 124.3 0.3 8.9e-17 61.4 0.1 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EER29778.1 - 9.7e-20 71.0 0.0 2.2e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER29778.1 - 3.8e-08 33.5 0.0 1.9e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EER29778.1 - 0.13 12.6 0.2 31 4.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain Kelch_5 PF13854.6 EER29780.1 - 1.4e-18 66.5 2.9 3e-15 55.8 0.9 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EER29780.1 - 1.8e-07 31.3 5.4 0.0091 16.3 0.1 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EER29780.1 - 2.5e-05 24.0 0.7 0.026 14.5 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_4 PF13418.6 EER29780.1 - 2.8e-05 24.0 0.7 0.027 14.5 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EER29780.1 - 5e-05 23.4 1.1 0.007 16.6 0.1 3.7 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.25 EER29780.1 - 9.1e-05 22.0 3.1 0.024 14.2 0.2 3.8 3 0 0 3 3 3 1 Kelch motif stn_TNFRSF12A PF12191.8 EER29780.1 - 0.023 14.9 0.2 0.048 13.9 0.2 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain PetG PF02529.15 EER29780.1 - 0.063 13.1 0.5 0.15 12.0 0.5 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF4381 PF14316.6 EER29780.1 - 0.19 11.9 1.3 0.41 10.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF5385 PF17359.2 EER29780.1 - 0.26 10.8 0.0 0.37 10.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) Thiolase_N PF00108.23 EER29781.1 - 2.7e-16 59.7 0.0 1e-11 44.7 0.0 2.8 2 1 1 3 3 3 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 EER29781.1 - 4.1e-11 42.6 0.3 4e-10 39.4 0.3 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EER29781.1 - 1.7e-06 27.9 0.5 1.4e-05 24.8 0.5 2.1 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EER29781.1 - 5.2e-05 23.0 0.3 0.0076 16.1 0.2 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GMC_oxred_N PF00732.19 EER29782.1 - 2.2e-44 152.0 0.3 3.4e-44 151.4 0.3 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EER29782.1 - 4.1e-29 101.9 0.1 8.1e-28 97.8 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EER29782.1 - 3.2e-05 23.2 0.4 6e-05 22.3 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EER29782.1 - 0.00033 20.0 0.5 0.0012 18.1 0.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EER29782.1 - 0.0014 17.9 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EER29782.1 - 0.0022 17.3 0.1 0.0049 16.1 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EER29782.1 - 0.018 15.3 0.2 0.066 13.5 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EER29782.1 - 0.2 10.9 0.0 4.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FA_hydroxylase PF04116.13 EER29784.1 - 1.5e-24 86.9 15.9 1.6e-24 86.8 12.0 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RHH_1 PF01402.21 EER29784.1 - 0.089 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family TCTP PF00838.17 EER29785.1 - 5.6e-61 205.7 0.3 6.9e-61 205.4 0.3 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein FliE PF02049.18 EER29785.1 - 0.067 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE DUF3627 PF12299.8 EER29785.1 - 0.1 12.7 0.0 0.3 11.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3627) SRP19 PF01922.17 EER29786.1 - 5.4e-34 117.0 0.0 8.1e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Fungal_trans PF04082.18 EER29787.1 - 4.4e-13 48.9 0.0 1.3e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29787.1 - 5.3e-11 42.5 8.0 9.8e-11 41.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 EER29789.1 - 2.8e-09 37.8 0.4 4.1e-09 37.2 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AbiEii PF08843.11 EER29791.1 - 4.3e-05 23.6 0.0 0.00029 20.9 0.0 2.0 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system Ribosomal_S5_C PF03719.15 EER29791.1 - 0.15 11.6 0.1 7.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Pkinase PF00069.25 EER29792.1 - 5e-14 52.3 0.0 1e-13 51.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29792.1 - 6.5e-13 48.6 0.0 9.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EER29792.1 - 0.00029 20.5 0.0 0.00056 19.6 0.0 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EER29792.1 - 0.0018 18.2 0.1 0.0046 16.9 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EER29792.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EER29792.1 - 0.071 12.5 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EER29794.1 - 5.7e-15 55.9 0.1 2e-14 54.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EER29794.1 - 0.0027 16.6 0.0 0.21 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.14 EER29794.1 - 0.018 14.4 0.3 3.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family La_HTH_kDCL PF18177.1 EER29794.1 - 0.028 14.7 0.0 0.085 13.2 0.0 1.8 1 0 0 1 1 1 0 La HTH in kinetoplastid DICER domain Pkinase PF00069.25 EER29794.1 - 0.15 11.4 0.0 0.57 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain p450 PF00067.22 EER29795.1 - 4.6e-57 193.8 0.0 6.1e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EER29796.1 - 5.1e-16 59.0 0.0 7.9e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EER29796.1 - 6.3e-09 36.4 0.0 1.7e-08 35.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EER29796.1 - 4.5e-06 26.5 0.0 5.2e-05 23.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EER29796.1 - 9.5e-05 23.0 0.0 0.0003 21.4 0.0 1.9 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EER29796.1 - 0.00018 22.2 0.0 0.0011 19.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EER29796.1 - 0.00025 20.7 0.0 0.00086 18.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EER29796.1 - 0.00072 19.3 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EER29796.1 - 0.022 14.1 0.0 0.093 12.0 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain PrmA PF06325.13 EER29796.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EER29796.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 EER29796.1 - 0.16 11.4 0.0 0.39 10.1 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Thioesterase PF00975.20 EER29797.1 - 1e-15 58.5 0.0 2.1e-15 57.5 0.0 1.5 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 EER29797.1 - 6.6e-08 33.4 0.0 7.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EER29797.1 - 0.0027 17.4 0.0 0.0041 16.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EER29797.1 - 0.0028 17.5 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EER29797.1 - 0.021 14.7 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold p450 PF00067.22 EER29799.1 - 2.2e-10 39.9 0.0 3e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EER29800.1 - 1.7e-25 89.7 40.5 3.7e-25 88.6 40.4 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EER29800.1 - 8.5e-06 24.9 8.0 8.5e-06 24.9 8.0 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter Hamartin PF04388.12 EER29800.1 - 0.2 10.3 0.1 0.31 9.7 0.1 1.2 1 0 0 1 1 1 0 Hamartin protein Phage_holin_5_2 PF16079.5 EER29800.1 - 7 7.1 6.8 3.9 7.9 2.1 2.9 2 1 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V HisKA PF00512.25 EER29801.1 - 0.057 13.5 2.2 0.48 10.5 1.7 2.4 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain OrfB_Zn_ribbon PF07282.11 EER29801.1 - 0.14 12.1 1.3 0.39 10.7 1.3 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain AA_permease PF00324.21 EER29802.1 - 1e-141 472.8 39.3 1.2e-141 472.6 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EER29802.1 - 2.5e-40 138.6 41.3 3e-40 138.3 41.3 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_4 PF01063.19 EER29803.1 - 5.7e-22 78.7 0.0 7.1e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Cytokin_check_N PF10407.9 EER29804.1 - 1.4e-06 28.1 0.0 3.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Pkinase PF00069.25 EER29805.1 - 8.4e-42 143.4 0.0 2.6e-30 105.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Ribonuc_2-5A PF06479.12 EER29805.1 - 1.9e-40 138.0 0.0 3.1e-40 137.3 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EER29805.1 - 6.1e-21 74.9 0.0 5.2e-20 71.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EER29805.1 - 0.00044 20.0 0.1 0.46 10.5 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat Kdo PF06293.14 EER29805.1 - 0.0028 17.0 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EER29805.1 - 0.0072 15.2 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Pro_isomerase PF00160.21 EER29806.1 - 3.2e-51 173.7 0.1 6.9e-51 172.6 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EER29806.1 - 1.2e-10 41.8 0.0 0.0028 18.4 0.0 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EER29806.1 - 0.073 12.0 0.5 0.71 8.8 0.5 2.0 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 EER29806.1 - 0.078 13.3 0.0 4.4 7.7 0.0 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain CRM1_C PF08767.11 EER29806.1 - 0.093 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 CRM1 C terminal Cpn60_TCP1 PF00118.24 EER29807.1 - 2e-142 475.3 12.6 2.3e-142 475.1 12.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EER29807.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF5442 PF17514.2 EER29807.1 - 0.16 12.2 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) Pkinase PF00069.25 EER29808.1 - 9.9e-11 41.5 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29808.1 - 1.3e-05 24.7 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EER29809.1 - 4.2e-26 91.9 0.0 2.2e-25 89.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29809.1 - 2.6e-11 43.3 0.0 3.3e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER29809.1 - 0.0088 14.9 0.1 0.052 12.3 0.0 1.8 1 1 1 2 2 2 1 Fungal protein kinase DUF1981 PF09324.10 EER29809.1 - 0.12 12.3 0.1 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) TFB6 PF17110.5 EER29810.1 - 0.003 17.3 1.0 0.0036 17.0 1.0 1.1 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Otopetrin PF03189.13 EER29810.1 - 0.0034 16.3 0.2 0.0048 15.8 0.2 1.2 1 0 0 1 1 1 1 Otopetrin DUF3439 PF11921.8 EER29810.1 - 0.0057 16.6 3.1 0.0057 16.6 3.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Folate_carrier PF01770.18 EER29810.1 - 0.22 10.2 0.1 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier OAD_gamma PF04277.13 EER29810.1 - 0.53 10.9 4.6 0.93 10.1 4.6 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3537 PF12056.8 EER29810.1 - 0.57 8.9 2.4 0.64 8.8 2.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3537) FAM176 PF14851.6 EER29810.1 - 0.73 9.5 5.5 1 9.0 5.5 1.2 1 0 0 1 1 1 0 FAM176 family Connexin PF00029.19 EER29810.1 - 1.1 9.0 4.2 0.34 10.6 1.5 1.5 2 0 0 2 2 2 0 Connexin Pox_Ag35 PF03286.14 EER29810.1 - 1.1 9.0 11.8 1.6 8.5 11.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF3464 PF11947.8 EER29810.1 - 2.6 7.8 10.3 4.1 7.1 10.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Peptidase_S49_N PF08496.10 EER29810.1 - 5.5 7.0 10.7 7.8 6.6 10.7 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Acetyltransf_1 PF00583.25 EER29811.1 - 4.3e-05 23.7 0.0 8.1e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EER29811.1 - 0.018 15.4 0.0 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EER29811.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EER29811.1 - 0.2 11.8 0.0 0.37 11.0 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FAM24 PF15193.6 EER29812.1 - 0.18 12.6 0.0 0.45 11.3 0.0 1.6 1 0 0 1 1 1 0 FAM24 family Pam17 PF08566.10 EER29814.1 - 3.8e-69 231.8 0.1 6.6e-69 231.0 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2505 PF10698.9 EER29814.1 - 0.0044 17.1 0.2 0.0069 16.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) bZIP_C PF12498.8 EER29814.1 - 0.017 16.1 0.8 0.017 16.1 0.8 1.6 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Vpu PF00558.19 EER29814.1 - 0.24 11.2 0.0 0.55 10.0 0.0 1.6 1 0 0 1 1 1 0 Vpu protein Far-17a_AIG1 PF04750.14 EER29815.1 - 1.8e-42 145.0 6.0 2.1e-42 144.8 6.0 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Sec34 PF04136.15 EER29815.1 - 0.063 13.2 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Sec34-like family DUF3602 PF12223.8 EER29816.1 - 1.9e-17 63.6 8.1 1e-12 48.4 0.3 3.5 1 1 3 4 4 4 3 Protein of unknown function (DUF3602) VacA2 PF03077.14 EER29816.1 - 0.04 13.8 0.5 4.2 7.3 0.0 2.4 2 0 0 2 2 2 0 Putative vacuolating cytotoxin Fungal_trans_2 PF11951.8 EER29817.1 - 3.4e-34 118.3 0.1 5.3e-34 117.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29817.1 - 0.06 13.5 1.7 0.13 12.4 1.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Velvet PF11754.8 EER29818.1 - 2e-92 309.7 0.0 2.5e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 Velvet factor NAD_binding_10 PF13460.6 EER29819.1 - 4.1e-10 39.8 0.0 1.5e-09 38.0 0.0 1.9 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EER29819.1 - 8.8e-10 38.5 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Sacchrp_dh_NADP PF03435.18 EER29819.1 - 0.048 13.9 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DLH PF01738.18 EER29820.1 - 4.4e-31 108.1 0.0 4.9e-31 108.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EER29820.1 - 0.028 14.0 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 EER29820.1 - 0.1 12.5 0.0 1.9 8.4 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal SWIB PF02201.18 EER29821.1 - 3.2e-27 94.2 0.0 5.9e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Ndc1_Nup PF09531.10 EER29821.1 - 0.56 8.8 4.2 0.56 8.8 4.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CEND1 PF15677.5 EER29821.1 - 9 6.8 22.3 8.3 7.0 14.1 2.2 1 1 1 2 2 2 0 Cell cycle exit and neuronal differentiation protein 1 eIF2A PF08662.11 EER29822.1 - 2.3e-37 128.7 2.3 1.1e-34 120.1 0.9 3.8 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EER29822.1 - 1.3e-06 28.1 0.0 3.2e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP3 PF08572.10 EER29822.1 - 0.0031 17.3 0.2 0.0065 16.2 0.2 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) WD40 PF00400.32 EER29822.1 - 0.0071 17.2 0.6 0.33 11.9 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Glyoxalase PF00903.25 EER29823.1 - 0.0012 19.1 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_S10 PF00450.22 EER29824.1 - 7.9e-119 397.8 0.0 9.2e-119 397.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EER29824.1 - 0.0012 19.4 0.0 0.003 18.1 0.0 1.6 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Fungal_trans PF04082.18 EER29825.1 - 3.2e-12 46.0 2.4 1.3e-11 44.1 0.8 2.3 2 1 1 3 3 3 1 Fungal specific transcription factor domain RSN1_7TM PF02714.15 EER29827.1 - 4.9e-88 295.0 20.7 7.4e-88 294.4 20.7 1.3 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 EER29827.1 - 1.3e-29 102.2 0.1 4e-29 100.6 0.1 1.8 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 EER29827.1 - 1.9e-29 103.1 0.0 4.2e-29 102.0 0.0 1.6 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EER29827.1 - 1.1e-13 51.2 0.5 1.1e-13 51.2 0.5 2.4 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport Curto_V3 PF07436.11 EER29827.1 - 0.1 13.0 0.4 0.28 11.6 0.4 1.7 1 0 0 1 1 1 0 Curtovirus V3 protein zf-C3HC4_3 PF13920.6 EER29828.1 - 2e-07 30.8 9.4 2e-07 30.8 9.4 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EER29828.1 - 7.8 6.4 20.9 0.098 12.5 10.9 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.21 EER29829.1 - 2.1e-63 213.8 1.2 3.7e-63 213.0 1.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EER29829.1 - 6.8e-30 104.7 2.9 6.8e-30 104.7 2.9 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EER29829.1 - 1.3e-10 41.7 0.3 4.4e-10 40.0 0.3 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EER29829.1 - 2.9e-10 40.3 2.5 3.2e-10 40.2 0.3 2.3 3 0 0 3 3 3 1 MutS family domain IV AAA_27 PF13514.6 EER29829.1 - 0.017 14.7 0.1 0.86 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 EER29830.1 - 2.2e-59 196.0 29.4 3.9e-11 43.3 0.7 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER29830.1 - 3.2e-22 78.6 4.2 0.00015 22.0 0.1 6.4 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EER29830.1 - 7.4e-08 31.5 6.8 0.29 9.7 0.1 5.8 3 3 2 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.11 EER29830.1 - 2.6e-07 30.7 0.1 0.024 14.5 0.0 3.7 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EER29830.1 - 7.3e-06 25.2 0.5 0.074 12.0 0.0 5.1 3 3 3 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NLE PF08154.12 EER29830.1 - 0.00045 20.7 0.0 0.0014 19.1 0.0 1.8 2 0 0 2 2 2 1 NLE (NUC135) domain WD40_like PF17005.5 EER29830.1 - 0.003 17.0 0.0 12 5.1 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain FAD_binding_9 PF08021.11 EER29830.1 - 0.0064 16.7 0.0 0.33 11.2 0.0 2.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DUF4550 PF15084.6 EER29830.1 - 0.0084 16.5 0.1 0.056 13.9 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4550) TFIIIC_delta PF12657.7 EER29830.1 - 3.5 7.5 6.1 9.4 6.1 0.9 3.7 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term CAP PF00188.26 EER29831.1 - 2.3e-17 64.0 7.0 7.3e-17 62.4 6.5 2.0 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Sec10 PF07393.11 EER29832.1 - 1.6e-166 555.8 4.7 2e-166 555.5 4.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 EER29832.1 - 0.00036 20.3 0.0 0.00089 19.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EER29832.1 - 0.0013 18.5 0.2 0.0053 16.6 0.0 2.0 2 0 0 2 2 2 1 F-box domain Vps53_N PF04100.12 EER29832.1 - 0.019 14.0 0.0 1.3 7.9 0.0 2.7 3 0 0 3 3 3 0 Vps53-like, N-terminal AAA PF00004.29 EER29833.1 - 8.3e-21 74.8 0.0 1.3e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytochrom_C1 PF02167.15 EER29834.1 - 1.5e-91 306.0 0.0 1.9e-91 305.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EER29834.1 - 0.013 15.8 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EER29834.1 - 0.11 13.7 0.0 0.42 11.8 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c AIG2_2 PF13772.6 EER29835.1 - 0.00026 21.3 0.1 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.20 EER29837.1 - 2.7e-105 351.2 0.0 3.4e-105 350.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RSN1_7TM PF02714.15 EER29838.1 - 5.1e-83 278.6 21.0 5.1e-83 278.6 21.0 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EER29838.1 - 6.2e-42 143.8 0.0 8.7e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EER29838.1 - 2.5e-41 141.0 1.2 2.5e-41 141.0 1.2 2.8 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport Anoctamin PF04547.12 EER29838.1 - 0.0014 17.6 1.9 0.0014 17.6 1.9 2.4 3 0 0 3 3 3 1 Calcium-activated chloride channel hDGE_amylase PF14701.6 EER29839.1 - 9.2e-176 585.2 0.0 1.2e-175 584.8 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EER29839.1 - 2.8e-125 418.2 0.2 6.3e-125 417.1 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EER29839.1 - 2.2e-83 279.8 0.0 3.7e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme Alpha-amylase PF00128.24 EER29839.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Nbl1_Borealin_N PF10444.9 EER29839.1 - 0.051 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal SLX9 PF15341.6 EER29840.1 - 5e-39 133.7 7.5 7e-39 133.2 7.5 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 CBM46 PF18448.1 EER29840.1 - 0.13 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain NAD_Gly3P_dh_C PF07479.14 EER29841.1 - 5.5e-44 149.9 0.1 9.1e-44 149.2 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 EER29841.1 - 1.8e-37 128.8 0.0 5.1e-37 127.3 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.21 EER29842.1 - 4.8e-59 199.7 0.0 7.4e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EER29842.1 - 3.3e-10 40.5 0.0 1.9e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 EER29842.1 - 0.013 15.5 0.1 0.035 14.2 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EER29842.1 - 0.03 13.6 1.1 0.081 12.2 1.1 1.7 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.6 EER29842.1 - 0.036 14.5 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EER29842.1 - 0.047 13.3 0.0 0.094 12.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DPBB_1 PF03330.18 EER29843.1 - 1.2e-07 31.9 0.0 2.2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EER29843.1 - 0.036 13.9 0.1 0.055 13.3 0.1 1.2 1 0 0 1 1 1 0 Barwin family DLH PF01738.18 EER29846.1 - 4.2e-13 49.3 0.0 5.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Zn_clus PF00172.18 EER29847.1 - 8.4e-08 32.2 6.5 1.2e-07 31.7 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 EER29848.1 - 1.2e-16 60.0 1.6 2.3e-16 59.1 1.6 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EER29848.1 - 0.16 11.8 3.2 0.29 11.0 3.2 1.5 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) zf-C2H2 PF00096.26 EER29849.1 - 6.1e-12 45.3 12.2 2.8e-06 27.5 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER29849.1 - 1.3e-08 34.9 10.3 0.00043 20.9 1.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EER29849.1 - 1.5e-06 28.4 13.6 6.4e-05 23.2 4.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EER29849.1 - 1.8e-05 24.9 3.2 0.006 16.8 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER29849.1 - 0.0049 17.2 4.1 0.91 10.0 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type BolA PF01722.18 EER29849.1 - 0.05 13.9 0.1 0.83 10.0 0.0 2.4 1 1 1 2 2 2 0 BolA-like protein zf-H2C2_5 PF13909.6 EER29849.1 - 0.061 13.1 0.5 0.061 13.1 0.5 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EER29849.1 - 0.13 12.3 9.8 0.84 9.7 0.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 EER29849.1 - 0.4 11.2 9.1 0.9 10.0 1.7 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 EER29849.1 - 0.51 10.1 3.9 5.6 6.8 0.5 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type Dynamin_N PF00350.23 EER29850.1 - 4.2e-31 108.3 0.0 9e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EER29850.1 - 3.4e-28 98.7 0.0 7.4e-21 74.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EER29850.1 - 1.9e-06 28.0 0.1 1.3e-05 25.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 EER29850.1 - 0.00024 21.2 4.4 0.0004 20.5 0.6 3.0 3 0 0 3 3 3 1 Dynamin GTPase effector domain AAA_15 PF13175.6 EER29850.1 - 0.035 13.8 0.1 0.3 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain DUF1151 PF06625.11 EER29850.1 - 0.039 13.9 0.9 0.63 10.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) AAA_29 PF13555.6 EER29850.1 - 0.041 13.6 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med26_C PF15693.5 EER29850.1 - 0.052 13.7 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Mediator complex subunit 26 C-terminal AAA_21 PF13304.6 EER29850.1 - 0.053 13.3 0.0 0.15 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 EER29850.1 - 0.11 12.8 0.1 6.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EER29850.1 - 0.11 12.9 0.1 0.54 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Transp_cyt_pur PF02133.15 EER29851.1 - 9.1e-103 344.4 31.2 1.1e-102 344.1 31.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF917 PF06032.12 EER29852.1 - 1.7e-127 425.1 0.2 1.2e-126 422.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EER29852.1 - 1.9e-30 106.1 6.5 4.3e-26 91.9 1.2 3.3 2 1 1 3 3 3 3 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EER29852.1 - 1.6e-27 96.3 3.7 7e-27 94.3 0.0 3.1 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.6 EER29852.1 - 3.7e-05 22.5 3.6 0.014 14.1 0.3 3.3 3 0 0 3 3 3 2 MutL protein FtsA PF14450.6 EER29852.1 - 0.0014 19.0 3.1 0.85 10.1 0.0 3.4 2 1 0 2 2 2 2 Cell division protein FtsA ROK PF00480.20 EER29852.1 - 0.0027 17.2 0.1 0.0073 15.8 0.1 1.8 1 0 0 1 1 1 1 ROK family BcrAD_BadFG PF01869.20 EER29852.1 - 0.0028 17.2 1.8 0.0043 16.6 0.2 2.2 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family BRE PF06113.12 EER29852.1 - 0.08 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) Pyridoxal_deC PF00282.19 EER29853.1 - 2.2e-61 207.7 0.0 3.2e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EER29853.1 - 0.0034 16.4 0.0 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Fungal_trans_2 PF11951.8 EER29854.1 - 1.4e-58 198.5 0.2 1.8e-58 198.2 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29854.1 - 1.1e-06 28.6 12.8 2e-06 27.8 12.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.8 EER29855.1 - 1.8e-14 53.5 3.7 2.8e-14 52.9 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) EutQ PF06249.12 EER29856.1 - 7.2e-13 48.6 0.0 7.9e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EER29856.1 - 1.1e-08 34.6 0.0 1.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EER29856.1 - 1.6e-05 24.5 0.0 2.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 EER29856.1 - 0.02 14.9 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Pirin Cupin_1 PF00190.22 EER29856.1 - 0.041 13.5 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Cupin DUF3857 PF12969.7 EER29856.1 - 0.096 12.7 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) Cupin_6 PF12852.7 EER29856.1 - 0.17 11.6 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Cupin Pkinase PF00069.25 EER29857.1 - 1.4e-59 201.6 0.0 1e-58 198.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29857.1 - 2.6e-29 102.3 0.6 9.5e-21 74.2 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EER29857.1 - 3.2e-05 23.4 0.6 0.00014 21.3 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EER29857.1 - 0.00015 21.8 5.5 0.089 12.7 0.1 3.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_C PF00433.24 EER29857.1 - 0.0031 18.2 0.4 0.0083 16.8 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EER29857.1 - 0.0032 16.5 0.0 0.006 15.6 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EER29857.1 - 0.014 14.8 0.0 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1687 PF07955.11 EER29858.1 - 4.5e-27 95.0 0.0 6.7e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) OppC_N PF12911.7 EER29860.1 - 0.036 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Mannosyl_trans3 PF11051.8 EER29860.1 - 0.16 11.3 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Fungal_trans PF04082.18 EER29861.1 - 2.8e-22 79.0 5.5 4e-22 78.5 4.7 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER29861.1 - 7.4e-06 26.0 8.6 7.4e-06 26.0 8.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Oxidored_q6 PF01058.22 EER29862.1 - 6e-23 81.1 0.0 7.8e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Abhydrolase_2 PF02230.16 EER29864.1 - 1.7e-57 194.8 0.0 5.2e-57 193.1 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EER29864.1 - 4.5e-07 30.0 0.0 0.0015 18.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EER29864.1 - 6e-06 25.9 0.1 0.00046 19.7 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EER29864.1 - 1.7e-05 24.4 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 EER29864.1 - 0.00027 20.7 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EER29864.1 - 0.00029 20.2 0.1 0.073 12.3 0.0 2.9 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Esterase PF00756.20 EER29864.1 - 0.016 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 EER29864.1 - 0.16 12.5 0.0 0.97 10.0 0.0 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EER29864.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Ctr PF04145.15 EER29866.1 - 3e-29 102.6 0.2 3.5e-29 102.3 0.2 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.19 EER29867.1 - 1.1e-19 70.8 11.2 3e-19 69.4 11.2 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EER29867.1 - 2.3e-18 66.3 0.0 4.4e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EER29867.1 - 1.8e-17 63.9 0.0 3.5e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain adh_short PF00106.25 EER29868.1 - 3.3e-23 82.2 0.0 7.6e-22 77.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER29868.1 - 2.8e-10 40.1 0.0 1.6e-08 34.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER29868.1 - 4.1e-09 36.6 0.0 6.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EER29868.1 - 0.006 15.7 0.0 0.07 12.3 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EER29868.1 - 0.013 15.8 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EER29868.1 - 0.097 12.1 0.0 6.5 6.1 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAC PF01849.18 EER29869.1 - 1.7e-24 85.5 0.3 3.4e-24 84.6 0.3 1.5 1 0 0 1 1 1 1 NAC domain MAGI_u1 PF16663.5 EER29869.1 - 0.012 15.6 1.0 0.031 14.4 0.0 2.0 2 0 0 2 2 2 0 Unstructured region on MAGI Med17 PF10156.9 EER29869.1 - 0.025 13.3 0.7 0.029 13.1 0.7 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Nup35_RRM PF05172.13 EER29870.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif His_Phos_2 PF00328.22 EER29871.1 - 7.8e-39 134.1 0.0 9e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FAD_binding_3 PF01494.19 EER29872.1 - 5e-72 243.1 0.1 3e-71 240.5 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EER29872.1 - 2e-31 109.3 0.0 3.7e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EER29872.1 - 0.03 13.5 0.1 0.096 11.9 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EER29872.1 - 0.063 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase SE PF08491.10 EER29872.1 - 0.08 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 EER29872.1 - 0.1 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.6 EER29872.1 - 0.13 12.5 0.1 0.31 11.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-C2H2 PF00096.26 EER29873.1 - 4.7e-08 33.1 13.9 0.0012 19.2 2.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER29873.1 - 3.7e-05 24.0 11.4 7.8e-05 22.9 1.6 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER29873.1 - 8.8e-05 23.0 12.8 0.039 14.8 3.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 EER29873.1 - 0.036 14.1 3.2 0.036 14.1 3.2 2.6 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.7 EER29873.1 - 0.1 13.0 4.0 0.21 12.1 1.9 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EER29873.1 - 0.84 9.7 5.6 0.13 12.3 1.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger BTB PF00651.31 EER29874.1 - 7.9e-30 103.3 0.4 1.3e-16 60.8 0.2 2.8 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 EER29874.1 - 4.8e-06 27.1 0.1 1.4e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER29874.1 - 9.7e-06 26.0 0.0 3.2e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EER29874.1 - 0.0001 22.6 0.1 0.012 16.0 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EER29874.1 - 0.00023 21.4 0.1 0.00077 19.7 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER29874.1 - 0.098 13.3 0.4 1.3 9.8 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat Pkinase PF00069.25 EER29875.1 - 1.8e-55 188.2 0.1 1.2e-33 116.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EER29875.1 - 5.6e-35 120.9 0.0 2.8e-23 82.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EER29875.1 - 0.013 14.9 0.1 0.054 12.8 0.0 2.0 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 EER29875.1 - 0.026 14.5 0.9 0.26 11.2 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EER29875.1 - 0.039 12.7 4.0 0.16 10.7 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase Nup_retrotrp_bd PF10599.9 EER29875.1 - 0.039 14.6 0.3 0.039 14.6 0.3 2.3 2 0 0 2 2 2 0 Retro-transposon transporting motif DUF99 PF01949.16 EER29875.1 - 0.13 11.7 0.4 0.25 10.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF99 DUF3896 PF13035.6 EER29875.1 - 9.4 6.5 9.0 0.45 10.7 0.7 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF3896) Wbp11 PF09429.10 EER29878.1 - 5.7e-22 77.9 14.8 5.7e-22 77.9 14.8 2.3 2 1 1 3 3 3 1 WW domain binding protein 11 BLOC1_2 PF10046.9 EER29879.1 - 0.01 16.1 0.5 0.38 11.1 0.4 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EER29879.1 - 0.053 13.6 0.7 0.14 12.2 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TraF_2 PF13729.6 EER29879.1 - 0.19 11.1 1.1 0.29 10.5 0.6 1.5 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein DEAD PF00270.29 EER29880.1 - 1.5e-36 125.8 0.0 2.8e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER29880.1 - 1.6e-26 92.8 0.0 2.7e-24 85.6 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER29880.1 - 8.2e-08 32.4 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EER29880.1 - 0.0056 16.1 0.1 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Lipase_3 PF01764.25 EER29881.1 - 1.5e-16 60.6 0.0 2.4e-15 56.7 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EER29881.1 - 0.0081 16.8 2.6 0.024 15.3 0.9 2.5 1 1 0 2 2 2 1 Alpha/beta hydrolase family APH PF01636.23 EER29882.1 - 1.1e-15 58.2 0.0 3.8e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 EER29882.1 - 0.0014 18.1 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.14 EER29882.1 - 0.057 12.6 0.0 0.26 10.4 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase Pkinase PF00069.25 EER29883.1 - 1.3e-15 57.5 0.0 1.5e-14 54.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29883.1 - 2.2e-07 30.4 0.0 6.4e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EER29885.1 - 1.2e-12 48.3 0.0 2.9e-12 47.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EER29885.1 - 0.00039 20.1 0.1 0.00084 19.0 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase DASH_Hsk3 PF08227.11 EER29887.1 - 1.2e-19 70.4 0.5 1.6e-19 70.0 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like ApbA PF02558.16 EER29888.1 - 1.2e-26 93.1 0.0 2.1e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EER29888.1 - 9.8e-22 77.5 0.0 1.6e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal SMC_N PF02463.19 EER29889.1 - 2.2e-22 79.6 0.0 3.5e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EER29889.1 - 3e-15 57.2 17.3 3e-15 57.2 17.3 6.0 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.6 EER29889.1 - 1.7e-10 41.1 7.5 5.5e-08 32.9 0.0 3.8 2 2 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 EER29889.1 - 7.7e-05 22.6 7.3 0.027 14.3 0.0 3.8 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system Baculo_PEP_C PF04513.12 EER29889.1 - 8.1e-05 22.7 7.0 3.5 7.7 0.1 4.6 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_29 PF13555.6 EER29889.1 - 8.8e-05 22.2 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF641 PF04859.12 EER29889.1 - 0.013 15.8 1.4 0.013 15.8 1.4 6.5 3 3 3 6 6 4 0 Plant protein of unknown function (DUF641) NACHT PF05729.12 EER29889.1 - 0.025 14.5 0.1 0.067 13.1 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_27 PF13514.6 EER29889.1 - 0.044 13.4 0.0 0.044 13.4 0.0 4.4 6 0 0 6 6 6 0 AAA domain ABC_tran PF00005.27 EER29889.1 - 0.057 13.9 0.0 0.057 13.9 0.0 4.0 3 2 0 3 3 2 0 ABC transporter AAA_25 PF13481.6 EER29889.1 - 0.14 11.7 0.0 0.14 11.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain NAAA-beta PF15508.6 EER29889.1 - 0.15 12.4 0.0 35 4.8 0.0 3.4 3 0 0 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAA PF00004.29 EER29889.1 - 0.2 12.1 1.2 0.91 9.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EER29889.1 - 0.46 10.9 0.0 0.46 10.9 0.0 4.0 4 1 0 4 4 3 0 AAA ATPase domain AAA_13 PF13166.6 EER29889.1 - 2.3 6.8 72.0 0.44 9.1 20.8 5.1 3 2 1 5 5 5 0 AAA domain AdoMet_MTase PF07757.13 EER29890.1 - 3.5e-38 130.4 0.4 2.3e-37 127.7 0.4 2.0 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase DUF3237 PF11578.8 EER29891.1 - 2.6e-32 111.7 0.0 3.7e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 EER29891.1 - 0.00047 20.1 4.6 0.21 11.6 0.5 2.5 2 0 0 2 2 2 2 BED zinc finger PyrI_C PF02748.15 EER29891.1 - 1 9.4 6.0 7.3 6.6 0.5 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Zn_Tnp_IS91 PF14319.6 EER29891.1 - 1.2 9.3 12.2 1.3 9.1 2.3 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain Gln-synt_C PF00120.24 EER29892.1 - 3.7e-80 269.5 0.0 4.5e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 EER29893.1 - 7.8e-61 205.6 0.1 8.9e-61 205.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EER29893.1 - 1.9e-41 141.7 0.0 2.4e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EER29893.1 - 2.8e-09 37.1 0.3 4.3e-09 36.5 0.3 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EER29893.1 - 0.00032 20.6 0.1 0.00063 19.7 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EER29893.1 - 0.0035 18.0 0.0 0.007 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 EER29893.1 - 0.0086 15.4 0.1 0.024 14.0 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RecC_C PF17946.1 EER29893.1 - 0.011 15.6 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 RecC C-terminal domain Epimerase PF01370.21 EER29893.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phos_pyr_kin PF08543.12 EER29893.1 - 0.048 13.0 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase MFS_1 PF07690.16 EER29894.1 - 2.3e-29 102.4 28.2 3e-29 102.1 28.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily CLN3 PF02487.17 EER29894.1 - 0.19 10.7 5.5 2.1 7.3 0.1 2.5 2 1 0 2 2 2 0 CLN3 protein Synaptobrevin PF00957.21 EER29895.1 - 8.1e-33 112.1 0.5 9.3e-33 111.9 0.5 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 EER29895.1 - 0.054 14.1 0.1 0.1 13.3 0.1 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor DUF1035 PF06281.12 EER29895.1 - 0.061 13.3 3.2 0.1 12.6 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) NAT PF04768.13 EER29896.1 - 2.4e-51 173.7 0.1 5.9e-51 172.5 0.0 1.7 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EER29896.1 - 2.2e-30 105.6 0.0 5.2e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EER29896.1 - 2.5e-27 96.1 0.3 6.6e-27 94.6 0.0 1.7 2 0 0 2 2 2 1 Amino acid kinase family Rad21_Rec8 PF04824.16 EER29897.1 - 0.04 13.2 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein Glyco_hydro_76 PF03663.14 EER29898.1 - 3.9e-160 533.3 7.1 4.5e-160 533.1 7.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EER29898.1 - 9.7e-05 21.6 9.5 0.0085 15.2 4.9 2.9 1 1 0 2 2 2 2 Glycosyl Hydrolase Family 88 CBP4 PF07960.11 EER29899.1 - 9.1e-34 116.1 1.3 1e-33 116.0 1.3 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 EER29899.1 - 0.018 14.9 0.4 0.046 13.6 0.0 1.7 1 1 1 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CemA PF03040.14 EER29899.1 - 0.021 14.8 0.2 0.024 14.6 0.2 1.0 1 0 0 1 1 1 0 CemA family FinO_N PF12602.8 EER29899.1 - 6.2 7.2 11.0 1.2 9.5 6.5 1.9 2 0 0 2 2 2 0 Fertility inhibition protein N terminal Sel1 PF08238.12 EER29900.1 - 1e-47 159.4 28.6 3.2e-09 37.1 0.2 7.6 7 0 0 7 7 7 7 Sel1 repeat TPR_20 PF14561.6 EER29900.1 - 0.033 14.5 1.9 0.053 13.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EER29900.1 - 0.039 14.3 0.1 17 6.1 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EER29900.1 - 4.4 7.9 14.8 46 4.6 0.7 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat ABC_tran PF00005.27 EER29902.1 - 4.1e-47 160.2 0.0 1.2e-25 90.6 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EER29902.1 - 1.3e-14 54.7 1.4 0.0031 17.4 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EER29902.1 - 4.3e-12 45.9 0.2 0.00096 18.6 0.0 4.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EER29902.1 - 2.5e-07 31.4 0.0 0.0051 17.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EER29902.1 - 2.6e-07 30.7 0.0 0.0076 16.3 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EER29902.1 - 2e-06 27.4 0.4 0.016 15.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EER29902.1 - 4.9e-06 26.6 0.2 0.14 12.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase Chromo PF00385.24 EER29902.1 - 8.2e-06 25.6 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF87 PF01935.17 EER29902.1 - 1.2e-05 25.5 1.3 0.0095 16.0 0.1 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_22 PF13401.6 EER29902.1 - 2.3e-05 24.7 0.0 0.3 11.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EER29902.1 - 2.4e-05 24.9 0.1 0.67 10.5 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.6 EER29902.1 - 0.00019 21.3 0.4 0.15 11.8 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain MeaB PF03308.16 EER29902.1 - 0.00023 20.3 0.2 0.11 11.4 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EER29902.1 - 0.00049 20.5 0.1 1.4 9.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EER29902.1 - 0.00079 19.7 0.0 0.04 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EER29902.1 - 0.0012 18.7 0.8 2.2 8.2 0.0 3.0 3 0 0 3 3 3 2 NACHT domain NB-ARC PF00931.22 EER29902.1 - 0.0019 17.5 0.3 1.6 7.8 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain AAA_16 PF13191.6 EER29902.1 - 0.0032 17.9 0.3 3.2 8.1 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EER29902.1 - 0.0032 17.6 0.0 5.2 7.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EER29902.1 - 0.0038 17.3 0.0 2.7 8.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF3584 PF12128.8 EER29902.1 - 0.0054 14.3 1.2 0.18 9.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_30 PF13604.6 EER29902.1 - 0.012 15.3 0.0 2.3 7.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain DRIM PF07539.12 EER29902.1 - 0.017 13.5 3.0 0.061 11.6 2.8 1.9 1 1 0 1 1 1 0 Down-regulated in metastasis AAA_24 PF13479.6 EER29902.1 - 0.018 14.7 0.5 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 EER29902.1 - 0.018 14.8 0.1 0.42 10.4 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal PduV-EutP PF10662.9 EER29902.1 - 0.02 14.7 0.0 0.65 9.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 EER29902.1 - 0.031 14.5 0.0 12 6.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 EER29902.1 - 0.038 13.9 0.0 1.9 8.4 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 DUF815 PF05673.13 EER29902.1 - 0.05 12.7 0.2 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EER29902.1 - 0.075 12.9 0.7 9.6 6.1 0.0 3.1 3 0 0 3 3 3 0 NTPase AAA PF00004.29 EER29902.1 - 0.083 13.3 0.1 27 5.2 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.25 EER29902.1 - 0.086 12.5 0.0 5 6.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ALF PF03752.13 EER29902.1 - 0.13 12.3 2.0 0.51 10.4 0.8 2.3 2 0 0 2 2 2 0 Short repeats of unknown function Dynamin_N PF00350.23 EER29902.1 - 0.13 12.3 0.0 2.2 8.3 0.0 3.1 3 0 0 3 3 3 0 Dynamin family Xpo1 PF08389.12 EER29902.1 - 0.18 11.8 0.5 0.67 10.0 0.0 2.2 2 1 0 2 2 2 0 Exportin 1-like protein AAA_13 PF13166.6 EER29902.1 - 0.25 9.9 1.7 4.6 5.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain Pox_A14 PF05767.12 EER29903.1 - 0.029 14.5 1.4 0.08 13.1 0.5 2.2 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF4389 PF14333.6 EER29903.1 - 0.52 10.3 4.5 0.6 10.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) SseC PF04888.12 EER29903.1 - 9.3 5.7 7.0 2.6 7.5 1.6 2.4 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Hom_end_hint PF05203.16 EER29904.1 - 0.0018 18.2 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint Hint PF01079.20 EER29904.1 - 0.0032 17.0 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 EER29904.1 - 0.065 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Hint domain AXH PF08517.12 EER29904.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) Vint PF14623.6 EER29904.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Hint-domain AA_permease_2 PF13520.6 EER29905.1 - 3.8e-47 161.1 51.0 4.6e-47 160.8 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EER29905.1 - 4e-20 71.9 38.9 5.5e-20 71.4 38.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4668 PF15701.5 EER29905.1 - 7.4 6.4 7.9 1.5 8.6 0.4 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4668) Glyco_hydro_3_C PF01915.22 EER29906.1 - 2.4e-44 151.7 0.0 4.4e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EER29906.1 - 2.2e-36 125.9 0.0 3.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EER29906.1 - 3.1e-21 75.3 1.2 1e-20 73.6 1.2 1.9 1 1 0 1 1 1 1 Fibronectin type III-like domain FMO-like PF00743.19 EER29907.1 - 1e-19 70.4 0.0 2e-17 62.8 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EER29907.1 - 1.9e-10 40.8 0.0 8e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EER29907.1 - 6.1e-07 29.0 0.0 0.0069 15.7 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EER29907.1 - 6.7e-06 25.5 0.1 0.00088 18.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EER29907.1 - 0.0004 19.7 0.1 0.99 8.6 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EER29907.1 - 0.00087 19.0 0.0 2.7 7.5 0.0 3.1 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EER29907.1 - 0.011 15.8 0.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 EER29907.1 - 0.011 14.5 0.1 0.02 13.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EER29907.1 - 0.011 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 EER29907.1 - 0.15 12.6 0.1 1.4 9.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FA_hydroxylase PF04116.13 EER29908.1 - 1.7e-25 89.9 24.6 1.5e-24 86.9 22.7 2.1 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Peptidase_M35 PF02102.15 EER29909.1 - 2.1e-106 355.9 1.5 2.5e-106 355.6 1.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EER29909.1 - 2e-43 148.4 3.2 2e-43 148.4 3.2 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase DUF2057 PF09829.9 EER29909.1 - 0.12 12.6 3.2 0.19 11.9 3.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Pkinase PF00069.25 EER29910.1 - 1.2e-27 96.9 0.0 1.5e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EER29910.1 - 1.4e-09 37.6 0.0 2.1e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EER29910.1 - 0.0013 17.6 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EER29910.1 - 0.13 11.6 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIP PF00230.20 EER29911.1 - 1.2e-49 169.0 7.3 1.5e-49 168.7 7.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF2644 PF10841.8 EER29911.1 - 0.039 14.2 0.7 0.37 11.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) FGGY_C PF02782.16 EER29912.1 - 5e-72 241.8 0.9 7.9e-72 241.1 0.9 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EER29912.1 - 2.8e-70 236.7 0.0 3.6e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Malate_synthase PF01274.22 EER29913.1 - 3.2e-231 768.2 0.0 3.6e-231 768.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase ADH_N PF08240.12 EER29915.1 - 3.1e-29 101.1 2.6 5.3e-29 100.3 2.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER29915.1 - 4.5e-20 71.9 0.0 7.3e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EER29915.1 - 9.7e-07 28.5 0.7 4.8e-06 26.2 0.7 1.9 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EER29915.1 - 6.5e-05 24.0 0.0 0.00012 23.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EER29915.1 - 0.0018 17.6 0.1 0.0031 16.8 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_assoc PF13823.6 EER29915.1 - 0.006 16.5 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Pyr_redox_2 PF07992.14 EER29915.1 - 0.02 14.1 0.3 0.028 13.7 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EER29915.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 ThiF family WW_like PF17890.1 EER29915.1 - 0.19 11.8 0.0 1.2 9.3 0.0 2.0 2 0 0 2 2 2 0 Peptidoglycan hydrolase LytB WW-like domain MPC PF03650.13 EER29916.1 - 5.3e-45 152.1 0.2 8.2e-45 151.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers L51_S25_CI-B8 PF05047.16 EER29917.1 - 2.4e-13 49.8 0.0 3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Glyco_hydro_36 PF17167.4 EER29917.1 - 0.093 11.4 0.0 0.11 11.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain LigB PF02900.18 EER29918.1 - 1.7e-34 119.2 0.0 2.1e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.25 EER29919.1 - 3.1e-27 95.3 0.1 1.2e-26 93.4 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER29919.1 - 4.9e-22 78.6 0.1 2e-21 76.6 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER29919.1 - 1.8e-05 24.7 0.5 0.00062 19.7 0.5 2.1 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EER29919.1 - 0.16 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Citrate_synt PF00285.21 EER29920.1 - 1.8e-98 329.9 0.0 2.2e-98 329.6 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain adh_short PF00106.25 EER29921.1 - 3.1e-23 82.3 0.0 5.1e-22 78.3 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER29921.1 - 1.8e-18 67.0 0.0 1.8e-17 63.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EER29921.1 - 0.00019 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EER29921.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Arylsulfotran_2 PF14269.6 EER29922.1 - 1e-120 402.7 0.1 1.5e-120 402.1 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EER29922.1 - 4.2e-12 45.7 0.0 2e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) CENP-C_mid PF15620.6 EER29922.1 - 0.14 12.2 0.8 0.26 11.2 0.2 1.6 2 0 0 2 2 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region B_lectin PF01453.24 EER29923.1 - 6.9e-06 26.5 0.0 0.0001 22.8 0.0 2.0 1 1 1 2 2 2 1 D-mannose binding lectin RHD_dimer PF16179.5 EER29923.1 - 0.021 14.8 0.7 0.69 10.0 0.1 2.2 1 1 1 2 2 2 0 Rel homology dimerisation domain RTA1 PF04479.13 EER29924.1 - 1.8e-73 246.6 1.7 2.5e-73 246.1 1.7 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 EER29925.1 - 2e-08 34.2 11.8 3.1e-08 33.6 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EER29925.1 - 0.00087 18.2 0.2 0.0014 17.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Beta-lactamase PF00144.24 EER29926.1 - 4.2e-10 39.4 0.0 4.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EER29926.1 - 0.013 14.9 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase PTR2 PF00854.21 EER29927.1 - 9.4e-35 120.2 4.1 1.7e-34 119.4 4.1 1.4 1 0 0 1 1 1 1 POT family DUF3254 PF11630.8 EER29927.1 - 0.093 12.9 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) ATPgrasp_N PF18130.1 EER29928.1 - 1.8e-20 73.3 0.0 3.7e-20 72.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 EER29928.1 - 3e-10 39.9 0.0 8.1e-10 38.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EER29928.1 - 1.3e-07 31.4 0.0 1.1e-06 28.3 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EER29928.1 - 0.00076 19.0 0.0 0.0025 17.3 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.14 EER29928.1 - 0.0021 18.1 0.0 0.01 15.9 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Abhydrolase_6 PF12697.7 EER29928.1 - 0.12 12.9 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LCCL PF03815.19 EER29929.1 - 9.5e-20 70.5 0.0 1.7e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain AMP-binding PF00501.28 EER29930.1 - 8.1e-60 202.6 0.0 1e-59 202.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER29930.1 - 1.5e-05 25.9 0.1 3.3e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.11 EER29930.1 - 2.6 7.8 0.0 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1661) PBP PF01161.20 EER29931.1 - 0.0033 17.7 0.0 0.0076 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MmgE_PrpD PF03972.14 EER29932.1 - 6.2e-146 486.4 0.0 7.9e-146 486.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ICL PF00463.21 EER29933.1 - 1.5e-198 660.6 0.1 1.7e-198 660.4 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EER29933.1 - 1.5e-09 37.7 0.1 5.8e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.9 EER29933.1 - 0.25 11.0 3.3 0.12 12.0 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DNA_methylase PF00145.17 EER29934.1 - 3.5e-28 98.9 0.0 5.2e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Gemini_AL3 PF01407.17 EER29934.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AL3 protein GATase_6 PF13522.6 EER29935.1 - 1.1e-12 48.4 0.0 2.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EER29935.1 - 2e-11 43.9 0.0 4.8e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EER29935.1 - 6e-09 35.6 0.0 1.2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EER29935.1 - 8.6e-05 21.6 0.0 0.00022 20.2 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DNA_ligase_OB PF03120.16 EER29935.1 - 0.13 12.2 0.0 21 5.1 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase OB-fold domain HhH-GPD PF00730.25 EER29936.1 - 3.2e-08 34.0 0.0 5.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SNAD1 PF18744.1 EER29936.1 - 0.13 12.1 0.0 0.28 11.0 0.0 1.5 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 1 Neuromodulin PF06614.11 EER29936.1 - 0.56 10.3 6.6 1.1 9.4 6.5 1.5 1 1 0 1 1 1 0 Neuromodulin Hamartin PF04388.12 EER29936.1 - 0.91 8.1 5.2 1.3 7.6 5.2 1.2 1 0 0 1 1 1 0 Hamartin protein Aldedh PF00171.22 EER29937.1 - 3.3e-115 385.2 0.0 4.1e-115 384.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adeno_E3_CR2 PF02439.15 EER29938.1 - 0.044 13.5 1.4 0.044 13.5 1.4 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Psm4 PF17063.5 EER29938.1 - 4.1 8.2 7.8 7.1 7.5 1.2 2.8 1 1 2 3 3 3 0 Phenol-soluble modulin alpha 4 peptide SseC PF04888.12 EER29938.1 - 4.2 6.9 6.3 6.3 6.3 6.1 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family SCAN PF02023.17 EER29939.1 - 0.086 12.7 1.9 0.21 11.4 0.3 2.4 2 1 0 2 2 2 0 SCAN domain Mt_ATP-synt_D PF05873.12 EER29941.1 - 6.9e-24 84.4 2.2 8.4e-24 84.2 2.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) CheZ PF04344.13 EER29941.1 - 0.028 14.4 0.4 0.037 13.9 0.4 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Calpain_inhib PF00748.19 EER29941.1 - 0.053 14.0 1.2 0.071 13.6 0.9 1.3 1 1 0 1 1 1 0 Calpain inhibitor TPR_MLP1_2 PF07926.12 EER29941.1 - 0.14 12.2 5.6 2 8.5 0.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Aida_N PF08910.10 EER29941.1 - 0.16 12.4 1.8 1.2 9.6 0.7 2.1 1 1 1 2 2 2 0 Aida N-terminus DUF2408 PF10303.9 EER29941.1 - 0.17 12.5 1.4 0.26 11.8 1.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Tropomyosin PF00261.20 EER29941.1 - 0.31 10.4 7.5 0.17 11.2 0.3 2.1 1 1 0 2 2 2 0 Tropomyosin NAC PF01849.18 EER29942.1 - 1.1e-22 79.8 0.0 7.8e-22 77.0 0.0 2.1 2 0 0 2 2 2 1 NAC domain Ribosomal_L14e PF01929.17 EER29943.1 - 2.8e-33 114.2 1.2 4.2e-33 113.7 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EER29943.1 - 2.9e-08 33.4 0.4 5.3e-08 32.6 0.4 1.4 1 0 0 1 1 1 1 KOW motif RGS PF00615.19 EER29944.1 - 5.1e-07 30.0 0.1 1.4e-05 25.4 0.1 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF5645 PF18713.1 EER29944.1 - 0.18 12.1 0.0 0.3 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) MFS_1 PF07690.16 EER29945.1 - 4.8e-39 134.3 37.4 2.7e-32 112.1 12.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EER29945.1 - 2.5e-13 49.7 8.2 3.6e-11 42.6 4.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EER29945.1 - 5.3e-07 28.8 3.7 7.2e-06 25.1 0.2 2.9 2 1 1 3 3 3 1 MFS_1 like family MFS_4 PF06779.14 EER29945.1 - 3.4e-05 23.3 2.2 3.4e-05 23.3 2.2 2.3 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Folate_carrier PF01770.18 EER29945.1 - 0.00042 19.2 0.1 0.00075 18.3 0.1 1.3 1 0 0 1 1 1 1 Reduced folate carrier LAP1C PF05609.12 EER29945.1 - 0.005 16.0 0.0 0.0074 15.4 0.0 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) MFS_2 PF13347.6 EER29945.1 - 0.023 13.3 17.0 0.013 14.1 4.8 3.1 2 2 1 3 3 3 0 MFS/sugar transport protein TRI12 PF06609.13 EER29945.1 - 0.027 12.9 1.3 0.05 12.0 1.3 1.4 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 EER29945.1 - 0.039 12.4 1.6 0.39 9.1 0.7 2.4 1 1 1 2 2 2 0 Transmembrane secretion effector SRP-alpha_N PF04086.13 EER29946.1 - 1.4e-72 245.1 0.0 2e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EER29946.1 - 1.1e-49 168.8 0.0 1.9e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EER29946.1 - 2.8e-09 37.0 0.0 7.6e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EER29946.1 - 4.4e-06 25.9 0.0 7.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EER29946.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EER29946.1 - 0.0031 17.3 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EER29946.1 - 0.0071 16.7 0.0 0.027 14.8 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_31 PF13614.6 EER29946.1 - 0.021 14.8 0.3 0.18 11.7 0.0 2.1 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 EER29946.1 - 0.024 14.7 0.0 0.14 12.2 0.0 2.3 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EER29946.1 - 0.027 13.9 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.27 EER29946.1 - 0.056 14.0 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 EER29946.1 - 0.061 13.4 0.1 0.28 11.3 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 EER29946.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 EER29946.1 - 0.079 12.9 0.1 0.34 10.8 0.1 2.1 2 1 0 2 2 2 0 NTPase ArsA_ATPase PF02374.15 EER29946.1 - 0.087 12.0 0.2 13 4.8 0.0 2.3 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_17 PF13207.6 EER29946.1 - 0.098 13.1 0.1 0.32 11.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain YIF1 PF03878.15 EER29947.1 - 1.4e-99 332.5 1.0 1.6e-99 332.2 1.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EER29947.1 - 0.13 12.0 10.8 0.076 12.7 8.7 1.6 2 0 0 2 2 2 0 Yip1 domain RNase_T PF00929.24 EER29948.1 - 2.8e-07 31.2 0.0 6.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Exonuclease Catalase PF00199.19 EER29949.1 - 2.6e-172 573.2 0.4 3.3e-172 572.9 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EER29949.1 - 5.2e-18 65.0 0.2 1e-17 64.1 0.2 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EER29949.1 - 4.7e-07 29.6 0.2 1.3e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EER29949.1 - 0.00044 20.1 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family HpcH_HpaI PF03328.14 EER29951.1 - 5.8e-22 77.9 0.0 7.8e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family p450 PF00067.22 EER29952.1 - 0.061 12.1 0.1 0.082 11.6 0.1 1.1 1 0 0 1 1 1 0 Cytochrome P450 NAD_binding_4 PF07993.12 EER29953.1 - 1.5e-32 112.7 0.0 2.4e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EER29953.1 - 8.7e-25 87.2 0.0 1.4e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 EER29953.1 - 5e-07 29.4 0.0 8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EER29953.1 - 2.8e-06 27.6 0.0 6.7e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site CGI-121 PF08617.10 EER29953.1 - 0.053 13.6 0.1 0.51 10.4 0.0 2.3 2 0 0 2 2 2 0 Kinase binding protein CGI-121 GalBD_like PF17974.1 EER29953.1 - 0.2 11.8 0.0 0.36 11.0 0.0 1.3 1 0 0 1 1 1 0 Galactose-binding domain-like KR PF08659.10 EER29953.1 - 0.31 10.9 0.0 0.31 10.9 0.0 2.6 4 0 0 4 4 4 0 KR domain MFS_1 PF07690.16 EER29954.1 - 2.5e-38 131.9 47.6 2.5e-38 131.9 47.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EER29954.1 - 1.2e-11 43.8 14.1 1.6e-11 43.3 14.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EER29954.1 - 7.2 4.8 13.1 1.1e+02 0.9 13.1 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DIT1_PvcA PF05141.12 EER29955.1 - 8.8e-98 327.2 0.0 1e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein RabGAP-TBC PF00566.18 EER29956.1 - 2e-39 135.5 1.4 3.8e-39 134.6 1.4 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EER29956.1 - 5.8e-07 29.1 0.0 2.2e-05 24.0 0.0 2.9 1 1 0 2 2 2 1 Rab-binding domain (RBD) GAS2 PF02187.17 EER29957.1 - 2e-06 27.8 0.2 4.4e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.12 EER29958.1 - 1.7e-110 368.7 0.0 2e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.7 EER29959.1 - 4.9e-109 364.6 0.2 7.2e-109 364.1 0.2 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 EER29959.1 - 4.6e-42 144.8 12.2 1.4e-41 143.3 12.2 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 EER29959.1 - 6e-34 117.2 0.0 1.7e-33 115.7 0.0 1.9 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PhoLip_ATPase_C PF16212.5 EER29960.1 - 1.8e-48 165.5 8.1 1.8e-48 165.5 8.1 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EER29960.1 - 6.1e-16 57.9 2.2 1.5e-15 56.6 2.2 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EER29960.1 - 9.7e-14 52.2 0.4 1.3e-08 35.4 0.5 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EER29960.1 - 2.3e-07 30.8 0.0 6.5e-06 26.1 0.0 2.7 2 1 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EER29960.1 - 1.2e-05 25.0 1.6 0.0024 17.4 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 EER29960.1 - 0.00074 19.3 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HIGH_NTase1_ass PF16581.5 EER29960.1 - 0.12 12.3 0.1 1.3 8.9 0.0 2.4 3 0 0 3 3 3 0 Cytidyltransferase-related C-terminal region Mso1_Sec1_bdg PF14475.6 EER29961.1 - 1.8e-12 46.6 0.1 3.2e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 EER29962.1 - 1.1e-39 135.8 0.7 1.8e-39 135.0 0.7 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 EER29962.1 - 4.2e-30 104.3 13.0 4.2e-30 104.3 13.0 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EER29962.1 - 1.9e-05 24.2 12.7 2.4e-05 23.9 12.7 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EER29962.1 - 0.06 13.1 0.4 0.091 12.5 0.4 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain LTV PF04180.14 EER29962.1 - 0.095 12.4 12.8 0.12 12.1 12.8 1.2 1 0 0 1 1 1 0 Low temperature viability protein Nop14 PF04147.12 EER29962.1 - 0.67 8.1 26.9 0.92 7.6 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EER29962.1 - 3.5 5.8 18.0 2.6 6.3 15.7 1.7 2 0 0 2 2 2 0 CDC45-like protein Amidase PF01425.21 EER29963.1 - 8.7e-96 321.6 0.0 7.4e-95 318.5 0.0 1.9 1 1 0 1 1 1 1 Amidase Ldh_2 PF02615.14 EER29964.1 - 2.5e-119 398.3 0.0 2.8e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Asp4 PF16996.5 EER29964.1 - 0.058 13.2 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 DUF3402 PF11882.8 EER29965.1 - 2.9e-189 630.0 0.0 4.5e-189 629.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EER29965.1 - 2.7e-83 279.5 0.0 4.2e-83 278.9 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein GST_N_2 PF13409.6 EER29965.1 - 0.043 14.1 0.2 0.88 9.9 0.0 2.7 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain PAP2 PF01569.21 EER29967.1 - 1.3e-14 54.1 4.0 1.3e-14 54.1 4.0 2.5 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EER29967.1 - 7.4e-05 22.9 0.0 0.02 15.0 0.0 2.4 2 1 0 2 2 2 2 Divergent PAP2 family UbiA PF01040.18 EER29967.1 - 0.0021 17.4 2.0 0.0021 17.4 2.0 1.9 2 0 0 2 2 2 1 UbiA prenyltransferase family 7TMR-DISM_7TM PF07695.11 EER29967.1 - 0.24 11.3 7.1 0.14 12.1 2.4 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling IBR PF01485.21 EER29968.1 - 6.4e-17 61.5 35.5 8.6e-13 48.3 0.5 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EER29968.1 - 7.3e-16 58.5 0.0 1.6e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-RING_11 PF17123.5 EER29968.1 - 0.0082 15.9 7.0 0.0082 15.9 7.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EER29968.1 - 0.025 14.9 10.8 0.025 14.9 10.8 4.1 3 1 1 4 4 4 0 Ring finger domain zf-RING_UBOX PF13445.6 EER29968.1 - 5 7.2 33.0 0.047 13.7 9.4 3.6 3 0 0 3 3 3 0 RING-type zinc-finger CRT10 PF08728.10 EER29969.1 - 2.3e-20 72.4 0.0 1.7e-12 46.4 0.0 2.2 2 0 0 2 2 2 2 CRT10 MMtag PF10159.9 EER29970.1 - 1.3e-33 115.0 3.0 1.3e-33 115.0 3.0 2.6 2 1 0 2 2 2 1 Multiple myeloma tumor-associated LPD15 PF18828.1 EER29970.1 - 0.21 11.5 3.4 0.32 10.9 1.1 2.2 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 Glyco_hydro_63 PF03200.16 EER29971.1 - 1.3e-176 588.2 0.2 2.1e-175 584.2 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EER29971.1 - 4.8e-89 298.3 0.0 2.7e-88 295.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EER29971.1 - 0.0006 18.8 0.5 0.041 12.7 0.0 2.3 1 1 0 2 2 2 2 Trehalase DAO PF01266.24 EER29972.1 - 8.2e-67 226.3 0.3 9.3e-67 226.1 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EER29972.1 - 9.2e-06 25.1 0.3 0.12 11.5 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EER29972.1 - 2.2e-05 24.6 0.3 4.7e-05 23.5 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EER29972.1 - 0.0073 15.4 0.6 0.087 11.9 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Sacchrp_dh_NADP PF03435.18 EER29972.1 - 0.018 15.3 0.4 0.16 12.2 0.2 2.4 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Prenylcys_lyase PF07156.14 EER29972.1 - 0.026 13.6 0.0 0.039 13.1 0.0 1.1 1 0 0 1 1 1 0 Prenylcysteine lyase Thi4 PF01946.17 EER29972.1 - 0.042 13.1 0.5 0.095 11.9 0.5 1.6 1 0 0 1 1 1 0 Thi4 family Mqo PF06039.15 EER29972.1 - 0.047 12.2 0.1 0.67 8.4 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) sCache_2 PF17200.4 EER29972.1 - 0.052 13.4 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 Single Cache domain 2 Pyr_redox PF00070.27 EER29972.1 - 0.14 12.7 1.7 0.4 11.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EER29972.1 - 0.16 10.8 1.4 0.98 8.2 0.4 2.0 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 EER29972.1 - 0.23 11.5 0.5 2.5 8.0 0.2 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Exo_endo_phos PF03372.23 EER29973.1 - 2.3e-05 24.0 0.1 4e-05 23.3 0.1 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M36 PF02128.15 EER29974.1 - 2.6e-164 546.8 3.3 3.3e-164 546.4 3.3 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 EER29974.1 - 4.8e-18 64.7 6.7 1.1e-17 63.6 6.7 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 EER29974.1 - 0.0088 15.9 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_S8 PF00082.22 EER29975.1 - 1.1e-20 74.1 11.0 2.2e-16 60.0 4.3 3.0 1 1 1 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 EER29975.1 - 5.4e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 SNRNP27 PF08648.12 EER29976.1 - 2.6e-26 91.4 3.4 4.9e-26 90.6 3.4 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Tube PF17212.3 EER29976.1 - 9.6e-05 22.5 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Tail tubular protein RSRP PF17069.5 EER29976.1 - 0.032 13.8 49.5 0.042 13.4 49.5 1.2 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Elong_Iki1 PF10483.9 EER29977.1 - 9.2e-105 350.4 0.0 1.1e-104 350.2 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.6 EER29978.1 - 5.9e-27 93.5 0.1 1e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EER29978.1 - 1.4e-14 53.6 0.0 2.6e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 EER29978.1 - 0.00095 19.2 2.1 0.019 15.0 0.1 2.3 1 1 1 2 2 2 2 Protein SLM4 ASXH PF13919.6 EER29979.1 - 6.2e-39 133.2 1.0 1.1e-38 132.3 1.0 1.5 1 0 0 1 1 1 1 Asx homology domain adh_short PF00106.25 EER29980.1 - 7.2e-24 84.3 0.1 2.7e-23 82.5 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EER29980.1 - 2.1e-17 63.5 0.0 3.9e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EER29980.1 - 0.0089 16.0 0.0 0.047 13.6 0.0 1.9 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 EER29980.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CLPTM1 PF05602.12 EER29981.1 - 5.1e-160 533.2 0.0 6.2e-160 532.9 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SBF PF01758.16 EER29981.1 - 0.057 13.1 0.2 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Sodium Bile acid symporter family 2TM PF13239.6 EER29981.1 - 5.4 7.4 7.9 1.6 9.1 0.4 3.3 2 1 0 2 2 2 0 2TM domain DUF4360 PF14273.6 EER29982.1 - 7.6e-72 240.9 1.4 8.8e-72 240.7 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CENP-I PF07778.11 EER29983.1 - 7.8e-40 137.1 1.0 5.2e-39 134.3 1.0 1.9 1 1 0 1 1 1 1 Mis6 PKHD_C PF18331.1 EER29983.1 - 0.12 12.5 0.2 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain Transcrip_reg PF01709.20 EER29984.1 - 6.1e-70 235.4 0.5 6.9e-70 235.2 0.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator Linker_histone PF00538.19 EER29984.1 - 0.054 13.9 0.3 0.58 10.6 0.2 2.4 2 0 0 2 2 2 0 linker histone H1 and H5 family HEAT PF02985.22 EER29985.1 - 1.4e-11 43.6 20.9 0.02 15.1 0.0 9.3 10 0 0 10 10 10 5 HEAT repeat Vac14_Fab1_bd PF12755.7 EER29985.1 - 3.5e-09 37.1 0.1 0.08 13.5 0.0 5.8 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EER29985.1 - 4.4e-09 36.6 4.2 0.00015 22.1 0.0 6.8 8 1 1 9 9 9 3 HEAT repeats Cnd1 PF12717.7 EER29985.1 - 1.3e-06 28.5 0.0 0.36 10.9 0.0 4.9 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EER29985.1 - 0.00038 20.1 0.7 2 7.9 0.0 4.4 4 0 0 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 EER29985.1 - 0.064 13.4 0.2 19 5.5 0.0 4.7 6 1 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EER29985.1 - 0.098 13.2 19.6 3.6 8.2 0.0 8.6 9 0 0 9 9 9 0 HEAT-like repeat DUF1640 PF07798.11 EER29986.1 - 2.5e-38 131.9 5.3 3.2e-38 131.5 5.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) HIP1_clath_bdg PF16515.5 EER29986.1 - 0.0069 17.0 6.1 0.018 15.6 6.1 1.7 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ALMT PF11744.8 EER29986.1 - 0.013 14.4 2.4 0.021 13.7 2.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Vps51 PF08700.11 EER29987.1 - 2e-12 47.0 0.0 9.1e-12 44.9 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 D123 PF07065.14 EER29988.1 - 1.1e-88 297.4 0.0 1.9e-88 296.6 0.0 1.3 1 0 0 1 1 1 1 D123 ECH_1 PF00378.20 EER29989.1 - 5.7e-26 91.3 0.0 6.6e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EER29989.1 - 7e-18 65.2 0.0 8.5e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pet100 PF09803.9 EER29990.1 - 2.8e-18 66.2 0.2 3.5e-18 65.9 0.2 1.1 1 0 0 1 1 1 1 Pet100 DUF5621 PF18532.1 EER29990.1 - 0.023 14.6 0.0 0.028 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5621) DUF3966 PF13110.6 EER29990.1 - 0.032 14.1 0.2 0.052 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) GEP5 PF17053.5 EER29990.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 SPT_ssu-like PF11779.8 EER29991.1 - 3.4e-24 84.2 4.8 4.7e-24 83.8 4.8 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like GMC_oxred_N PF00732.19 EER29992.1 - 7.3e-68 229.1 0.0 1.4e-67 228.1 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EER29992.1 - 1.4e-28 100.2 0.1 2.3e-28 99.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EER29992.1 - 1.4e-05 24.3 0.1 2.4e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EER29992.1 - 1.8e-05 24.0 0.3 0.00031 19.9 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EER29992.1 - 7.6e-05 22.9 0.1 0.00018 21.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EER29992.1 - 0.00012 21.4 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EER29992.1 - 0.00035 20.3 0.2 0.0021 17.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EER29992.1 - 0.00098 18.5 0.1 0.098 11.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EER29992.1 - 0.0011 18.3 0.1 0.0027 17.0 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EER29992.1 - 0.0088 14.8 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EER29992.1 - 0.052 14.1 0.0 0.31 11.6 0.0 2.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EER29992.1 - 0.12 12.6 0.0 0.3 11.4 0.0 1.6 2 0 0 2 2 2 0 TrkA-N domain BppU_IgG PF18667.1 EER29992.1 - 0.16 12.1 0.0 0.66 10.2 0.0 1.9 2 0 0 2 2 2 0 Baseplate upper protein immunoglobulin like domain RF-1 PF00472.20 EER29993.1 - 1.9e-23 82.6 7.3 2.2e-23 82.4 6.8 1.3 1 1 0 1 1 1 1 RF-1 domain XRN_M PF17846.1 EER29993.1 - 0.29 10.0 4.0 0.34 9.8 4.0 1.0 1 0 0 1 1 1 0 Xrn1 helical domain PBP_sp32 PF07222.12 EER29993.1 - 1 8.8 7.1 1.2 8.5 7.1 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CAS_CSE1 PF03378.15 EER29994.1 - 1.1e-192 640.5 0.0 1.9e-192 639.7 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EER29994.1 - 5e-157 522.5 0.8 7.3e-157 521.9 0.8 1.2 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EER29994.1 - 9.3e-15 54.3 0.3 3.5e-14 52.5 0.3 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EER29994.1 - 0.0097 16.0 0.2 0.24 11.4 0.0 3.5 4 1 0 4 4 4 1 Exportin 1-like protein SapB_2 PF03489.17 EER29994.1 - 0.36 11.0 2.0 2.5 8.3 0.0 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 2 DUF3384 PF11864.8 EER29995.1 - 2.8e-99 333.2 0.2 5.1e-99 332.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EER29995.1 - 2.2e-46 157.7 0.0 4.1e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EER29995.1 - 5.6e-39 134.2 0.0 5.8e-34 117.8 0.0 3.4 3 0 0 3 3 3 3 Tuberin PUF PF00806.19 EER29996.1 - 1.1e-57 188.6 13.6 2e-07 30.3 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EER29996.1 - 0.00016 22.0 3.0 2.4 8.5 0.9 4.5 2 1 3 5 5 5 1 CPL (NUC119) domain sCache_2 PF17200.4 EER29996.1 - 0.0057 16.5 2.5 2.9 7.7 0.0 4.7 4 1 1 5 5 5 1 Single Cache domain 2 LOB PF03195.14 EER29996.1 - 0.096 13.3 0.5 2.5 8.7 0.3 2.9 1 1 0 2 2 2 0 Lateral organ boundaries (LOB) domain PIN_8 PF18476.1 EER29996.1 - 0.18 11.7 0.9 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 PIN like domain Phosphodiest PF01663.22 EER29997.1 - 1e-15 58.2 0.3 1.6e-15 57.6 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EER29997.1 - 3.7e-06 26.5 0.7 6.9e-06 25.6 0.7 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EER29997.1 - 3.7e-05 23.3 0.1 5.7e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase DUF4337 PF14235.6 EER29997.1 - 0.045 13.9 0.2 12 6.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) PglZ PF08665.12 EER29997.1 - 0.11 12.6 2.7 5.9 6.9 0.2 3.0 3 0 0 3 3 3 0 PglZ domain cwf21 PF08312.12 EER29998.1 - 1.3e-13 50.8 21.3 1.3e-13 50.8 21.3 2.0 1 1 1 2 2 2 1 cwf21 domain bZIP_2 PF07716.15 EER29998.1 - 0.88 9.7 14.7 4.6 7.4 1.8 2.7 2 0 0 2 2 2 0 Basic region leucine zipper GvpL_GvpF PF06386.11 EER29998.1 - 7.7 6.4 12.7 2.5 8.0 10.0 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF HA2 PF04408.23 EER29999.1 - 3.7e-13 49.7 0.0 1.5e-12 47.8 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EER29999.1 - 8.2e-13 48.7 0.2 4.3e-12 46.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EER29999.1 - 4.3e-11 43.0 0.0 1.2e-10 41.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EER29999.1 - 4.7e-09 36.3 0.1 6.1e-08 32.6 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EER29999.1 - 9.7e-05 22.7 0.0 0.00032 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EER29999.1 - 0.0016 18.4 0.4 2.3 8.2 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EER29999.1 - 0.0066 17.0 6.6 0.071 13.6 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_19 PF13245.6 EER29999.1 - 0.0079 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EER29999.1 - 0.015 14.3 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.6 EER29999.1 - 0.04 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EER29999.1 - 0.055 12.7 0.6 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 EER29999.1 - 0.1 11.9 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MAT1 PF06391.13 EER29999.1 - 1.6 8.5 9.6 3.3 7.5 9.6 1.5 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 PAC3 PF10178.9 EER30000.1 - 1.9e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 DNA_gyraseA_C PF03989.13 EER30000.1 - 0.12 11.9 0.0 23 4.6 0.0 2.9 2 1 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Cohesin_load PF10345.9 EER30001.1 - 3.9e-164 547.4 14.1 4.9e-164 547.1 14.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 EER30001.1 - 8.1e-05 22.8 14.7 0.43 10.9 0.3 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat Lactamase_B_4 PF13691.6 EER30001.1 - 0.032 13.9 0.0 0.08 12.6 0.0 1.7 1 0 0 1 1 1 0 tRNase Z endonuclease Histone PF00125.24 EER30002.1 - 2.3e-41 141.2 0.1 6.4e-41 139.8 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EER30002.1 - 2.1e-05 24.6 0.1 3.7e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EER30002.1 - 0.00034 20.9 0.0 0.00047 20.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EER30002.1 - 0.099 12.9 0.2 0.21 11.9 0.2 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EMP70 PF02990.16 EER30003.1 - 4.3e-193 642.7 0.0 5.4e-193 642.4 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.23 EER30004.1 - 2e-20 72.3 0.0 3.1e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EER30004.1 - 2.7e-09 36.8 0.3 5.4e-09 35.8 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EER30004.1 - 4.8e-06 26.3 0.0 8.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EER30004.1 - 0.0035 17.9 0.0 0.0078 16.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EER30004.1 - 0.0063 16.6 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 EER30004.1 - 0.031 14.2 19.8 0.19 11.7 1.3 3.3 3 0 0 3 3 3 0 STI1 domain YukD PF08817.10 EER30004.1 - 0.048 14.4 0.0 0.11 13.2 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_2 PF14560.6 EER30004.1 - 0.056 13.9 0.1 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 EER30004.1 - 0.062 13.3 7.8 0.13 12.2 7.3 1.8 2 0 0 2 2 2 0 Spore germination GerD central core domain HOIP-UBA PF16678.5 EER30004.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 HOIP UBA domain pair DUF4127 PF13552.6 EER30004.1 - 0.23 10.0 0.0 0.32 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4127) XPC-binding PF09280.11 EER30004.1 - 4.3 7.1 20.5 1.1 9.0 10.6 3.7 2 1 1 3 3 3 0 XPC-binding domain MMS1_N PF10433.9 EER30005.1 - 1.3e-157 525.4 0.0 1.9e-157 524.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EER30005.1 - 4.1e-104 348.4 0.0 3.4e-103 345.3 0.0 2.4 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EER30005.1 - 0.021 15.1 0.0 0.58 10.5 0.0 3.3 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 EER30005.1 - 0.056 13.4 0.0 26 4.8 0.0 3.6 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal ALO PF04030.14 EER30008.1 - 1e-06 28.8 2.9 3.8e-06 26.9 2.9 1.8 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EER30008.1 - 4.5e-05 23.2 0.0 0.0037 17.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Chol_subst-bind PF09129.11 EER30008.1 - 0.003 16.6 5.1 1.1 8.2 0.7 3.1 2 1 0 2 2 2 2 Cholesterol oxidase, substrate-binding Pkinase_fungal PF17667.1 EER30009.1 - 7.9e-130 433.3 0.0 9.6e-130 433.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase CN_hydrolase PF00795.22 EER30010.1 - 4.8e-34 117.9 0.0 7.2e-34 117.3 0.0 1.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.12 EER30011.1 - 9.8e-42 142.5 0.4 8.6e-41 139.4 0.1 2.8 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EER30011.1 - 3.8e-24 85.3 2.1 2.1e-23 82.9 0.5 3.4 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 EER30011.1 - 1.3e-06 28.7 12.4 0.11 12.9 0.0 7.1 7 1 2 9 9 9 4 HEAT repeats HEAT_EZ PF13513.6 EER30011.1 - 0.00034 21.1 8.9 2.3 8.8 0.1 6.7 6 1 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 EER30011.1 - 0.00036 20.5 6.7 0.086 13.1 0.1 6.5 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.23 EER30011.1 - 0.077 13.1 7.5 2.3 8.4 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EER30011.1 - 0.11 12.2 3.4 45 3.7 0.0 4.8 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis Nipped-B_C PF12830.7 EER30011.1 - 2.2 8.2 5.3 35 4.3 0.1 4.8 5 1 0 5 5 5 0 Sister chromatid cohesion C-terminus NRDE-2 PF08424.10 EER30012.1 - 4.1e-94 315.3 0.1 2.4e-93 312.8 0.0 2.3 3 0 0 3 3 3 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EER30012.1 - 0.2 12.6 2.2 1.6e+02 3.5 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat UDG PF03167.19 EER30013.1 - 5.8e-18 65.4 0.0 9.1e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily 7TMR-DISM_7TM PF07695.11 EER30014.1 - 0.48 10.3 6.3 0.9 9.4 6.3 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.12 EER30015.1 - 7.2e-24 84.7 0.0 1.3e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EER30015.1 - 2.4e-23 82.3 0.0 4.8e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EER30015.1 - 9.5e-10 38.7 7.4 7.7e-09 35.7 3.3 2.5 1 1 1 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 EER30015.1 - 0.049 14.3 0.0 3.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.18 EER30016.1 - 3.9e-27 94.2 0.8 4.7e-27 93.9 0.8 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Phage_TAC_5 PF08890.11 EER30016.1 - 0.016 15.2 0.0 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC RhoGEF PF00621.20 EER30017.1 - 3.7e-06 27.3 0.0 9.4e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.29 EER30017.1 - 0.026 15.0 0.1 0.53 10.8 0.0 2.8 2 0 0 2 2 2 0 PH domain FTO_CTD PF12934.7 EER30017.1 - 0.12 12.1 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 FTO C-terminal domain Nas2_N PF18265.1 EER30018.1 - 2.3e-27 94.7 0.2 3.5e-27 94.1 0.2 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EER30018.1 - 1.3e-08 34.5 0.1 2.5e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EER30018.1 - 5e-06 26.8 0.0 1.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EER30018.1 - 1.5e-05 25.4 0.0 2.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EER30018.1 - 1.5e-05 25.2 0.3 3.3e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 PDZ domain Ras PF00071.22 EER30019.1 - 4.6e-49 166.1 0.0 5.7e-49 165.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EER30019.1 - 1.4e-29 102.8 0.0 3.4e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EER30019.1 - 7.3e-10 38.6 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EER30019.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EER30019.1 - 0.0013 19.1 0.1 0.01 16.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EER30019.1 - 0.0038 16.6 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EER30019.1 - 0.015 14.5 1.4 1.8 7.6 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 EER30019.1 - 0.023 14.2 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 EER30019.1 - 0.038 13.5 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EER30019.1 - 0.047 13.6 0.1 11 5.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EER30019.1 - 0.056 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EER30019.1 - 0.076 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 EER30019.1 - 0.081 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EER30019.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EER30019.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE STAS PF01740.21 EER30019.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 STAS domain SNF2_N PF00176.23 EER30020.1 - 1.7e-65 221.0 0.8 3.2e-65 220.2 0.8 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EER30020.1 - 6.5e-17 61.9 0.0 2.3e-16 60.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EER30020.1 - 4.2e-09 36.1 3.4 9e-09 35.1 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EER30020.1 - 1.4e-07 31.7 0.1 4.6e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 EER30020.1 - 1.8e-07 30.9 1.8 1.8e-07 30.9 1.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EER30020.1 - 2e-06 28.0 4.4 5.2e-06 26.7 4.4 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EER30020.1 - 4.2e-06 26.7 2.4 9.7e-06 25.5 2.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EER30020.1 - 2.1e-05 24.2 4.6 0.00011 21.9 4.6 2.2 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EER30020.1 - 3e-05 23.9 4.1 7.6e-05 22.6 4.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EER30020.1 - 4.4e-05 23.3 4.4 0.0001 22.1 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EER30020.1 - 0.00015 21.6 0.0 0.0006 19.6 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 EER30020.1 - 0.00019 21.2 6.8 0.0013 18.6 7.0 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EER30020.1 - 0.0047 17.1 5.7 0.01 16.0 5.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING CTNNBL PF08216.11 EER30020.1 - 0.14 12.3 1.5 0.53 10.5 1.5 2.0 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear DZR PF12773.7 EER30020.1 - 0.39 10.8 9.4 0.092 12.8 3.5 2.8 3 1 1 4 4 3 0 Double zinc ribbon zf-RING_11 PF17123.5 EER30020.1 - 2.8 7.8 6.4 7.5 6.4 6.4 1.8 1 0 0 1 1 1 0 RING-like zinc finger NAM-associated PF14303.6 EER30020.1 - 3.1 8.5 13.9 0.24 12.1 8.2 2.1 2 0 0 2 2 1 0 No apical meristem-associated C-terminal domain CDC45 PF02724.14 EER30020.1 - 4.7 5.4 10.1 8 4.6 10.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Fungal_trans PF04082.18 EER30021.1 - 3.9e-19 68.7 0.8 9.3e-19 67.5 0.8 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER30021.1 - 1.4e-10 41.1 10.7 1.4e-10 41.1 10.7 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EER30022.1 - 1.1e-26 92.5 14.9 2.5e-06 28.1 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER30022.1 - 3.6e-16 59.2 0.0 0.0084 16.4 0.0 5.3 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EER30022.1 - 3.4e-09 35.7 0.0 7.4e-06 24.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EER30022.1 - 0.00014 21.8 0.0 0.4 10.5 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EER30022.1 - 0.0026 16.7 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 EER30022.1 - 0.033 12.8 1.1 0.14 10.8 0.3 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 VID27 PF08553.10 EER30022.1 - 0.053 12.6 0.1 7.6 5.5 0.0 2.1 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 EER30022.1 - 0.15 11.0 0.0 0.43 9.6 0.0 1.7 1 1 1 2 2 2 0 Coatomer WD associated region Ge1_WD40 PF16529.5 EER30022.1 - 0.25 10.2 0.0 2.2 7.2 0.0 2.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribonuc_P_40 PF08584.11 EER30023.1 - 7.2e-59 199.4 0.0 1e-58 198.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Dna2 PF08696.11 EER30024.1 - 7.6e-68 228.3 0.0 1.3e-67 227.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 EER30024.1 - 3e-52 177.1 0.0 5e-52 176.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EER30024.1 - 2.7e-33 115.9 0.1 3.3e-17 63.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EER30024.1 - 1.1e-14 54.6 0.0 2.4e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EER30024.1 - 1.1e-10 42.1 0.3 3.2e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Cas_Cas4 PF01930.17 EER30024.1 - 9.8e-10 38.8 0.1 6.9e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 EER30024.1 - 6.3e-07 29.4 0.5 0.16 11.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EER30024.1 - 0.00026 20.6 0.0 0.00068 19.3 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 EER30024.1 - 0.00028 20.6 0.1 0.00056 19.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Csa1 PF06023.12 EER30024.1 - 0.00045 19.7 0.0 0.0013 18.2 0.0 1.7 1 1 0 1 1 1 1 CRISPR-associated exonuclease Csa1 Helicase_RecD PF05127.14 EER30024.1 - 0.00071 19.5 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 EER30024.1 - 0.006 17.0 1.2 0.011 16.2 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.6 EER30024.1 - 0.01 15.4 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 EER30024.1 - 0.016 15.2 0.5 0.099 12.7 0.1 2.5 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 EER30024.1 - 0.019 14.2 0.2 0.08 12.1 0.2 1.9 1 1 0 1 1 1 0 PIF1-like helicase TrwB_AAD_bind PF10412.9 EER30024.1 - 0.032 13.2 0.0 0.056 12.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 EER30024.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF87 PF01935.17 EER30024.1 - 0.05 13.7 1.3 0.31 11.1 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_5 PF07728.14 EER30024.1 - 0.072 13.1 0.1 0.21 11.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EER30024.1 - 0.074 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EER30024.1 - 0.079 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 EER30024.1 - 0.097 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mito_carr PF00153.27 EER30025.1 - 3.6e-53 177.5 2.0 4.8e-19 68.1 0.1 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein HLH PF00010.26 EER30026.1 - 2.7e-11 43.3 0.0 9.5e-11 41.5 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.12 EER30027.1 - 2.3e-33 115.0 18.1 3e-33 114.6 18.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family tRNA_lig_CPD PF08302.11 EER30028.1 - 1.1e-88 297.0 0.0 1.5e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 EER30028.1 - 9.2e-83 277.4 0.0 1.5e-82 276.7 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EER30028.1 - 2.9e-52 177.2 0.7 4.7e-52 176.4 0.7 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_18 PF13238.6 EER30028.1 - 0.045 14.3 0.3 0.39 11.3 0.2 2.5 3 0 0 3 3 3 0 AAA domain Ank_5 PF13857.6 EER30029.1 - 4.9e-12 45.8 0.2 2e-09 37.5 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EER30029.1 - 2.5e-08 34.3 0.0 1.5e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER30029.1 - 4.3e-06 27.2 0.0 1.1e-05 25.9 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EER30029.1 - 7.1e-06 26.0 0.0 6.1e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EER30029.1 - 0.00021 21.6 0.1 0.00089 19.6 0.1 2.1 1 0 0 1 1 1 1 Ankyrin repeat YejG PF13989.6 EER30029.1 - 0.041 14.3 0.0 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 YejG-like protein Mod_r PF07200.13 EER30030.1 - 1.7e-26 93.1 2.2 2.3e-26 92.6 2.2 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PAP2 PF01569.21 EER30031.1 - 1.6e-26 92.7 3.9 1.8e-26 92.5 1.8 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EER30031.1 - 0.52 10.0 10.4 0.65 9.7 0.1 2.6 3 0 0 3 3 3 0 PAP2 superfamily Aldo_ket_red PF00248.21 EER30032.1 - 2.6e-52 177.9 0.0 4.3e-52 177.2 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family DUF1720 PF08226.11 EER30033.1 - 0.084 13.3 0.2 0.23 11.9 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1720) NPR3 PF03666.13 EER30034.1 - 8.6e-152 506.2 0.1 1.1e-150 502.5 0.0 2.2 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 Mago-bind PF09282.10 EER30034.1 - 0.1 12.5 2.5 0.31 11.0 2.5 1.8 1 0 0 1 1 1 0 Mago binding La PF05383.17 EER30035.1 - 1.3e-18 66.7 0.3 2.6e-18 65.8 0.3 1.5 1 0 0 1 1 1 1 La domain Band_7 PF01145.25 EER30036.1 - 1.1e-31 110.2 0.6 2.1e-31 109.3 0.6 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EER30036.1 - 4.3e-24 84.3 1.3 1.3e-23 82.9 1.3 1.9 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 EER30036.1 - 0.06 12.6 0.2 0.087 12.1 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 EER30036.1 - 0.13 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Hira PF07569.11 EER30037.1 - 2e-81 273.0 0.0 1.9e-80 269.7 0.0 2.3 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EER30037.1 - 9.5e-28 95.9 25.3 6.3e-05 23.7 0.1 8.8 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EER30037.1 - 5.4e-13 49.1 0.0 0.085 13.2 0.0 6.3 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EER30037.1 - 9.7e-11 41.3 0.1 3.3e-10 39.6 0.1 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EER30037.1 - 1.5e-07 31.2 1.0 2.5 8.1 0.0 5.9 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EER30037.1 - 5.4e-05 22.3 0.2 2 7.3 0.0 5.0 3 1 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EER30037.1 - 0.014 13.4 0.0 0.029 12.4 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Mcl1_mid PF12341.8 EER30037.1 - 0.09 12.1 0.0 1.2 8.4 0.0 2.5 2 1 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region YchF-GTPase_C PF06071.13 EER30038.1 - 4.8e-34 116.4 0.2 1.3e-33 115.0 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EER30038.1 - 1.6e-16 60.4 0.0 6e-16 58.5 0.0 1.9 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EER30038.1 - 0.00083 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EER30038.1 - 0.056 13.5 0.2 0.26 11.4 0.2 2.2 2 1 0 2 2 2 0 TGS domain CBM_X2 PF03442.14 EER30038.1 - 0.092 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Pre-PUA PF17832.1 EER30039.1 - 2.5e-22 79.4 0.1 3.4e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EER30039.1 - 7.3e-14 51.5 0.0 1.3e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 PUA domain RIC1 PF07064.13 EER30040.1 - 3.7e-85 285.3 0.0 5.2e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 RIC1 SGTA_dimer PF16546.5 EER30041.1 - 8.3e-26 89.6 0.7 1.4e-25 88.8 0.7 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 EER30041.1 - 4.8e-13 48.1 6.1 0.00072 19.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EER30041.1 - 1.3e-12 46.9 3.2 0.00094 18.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER30041.1 - 1.9e-07 30.7 7.6 0.01 16.0 0.2 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EER30041.1 - 5.3e-07 29.2 6.4 0.00045 19.8 0.2 3.3 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.6 EER30041.1 - 2.3e-06 27.6 0.4 0.0051 17.1 0.1 3.2 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EER30041.1 - 3.3e-06 27.6 10.5 0.00073 20.1 5.9 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EER30041.1 - 5.6e-06 26.6 2.4 0.00079 19.7 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EER30041.1 - 1.9e-05 25.1 1.8 0.026 15.0 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EER30041.1 - 2e-05 25.0 7.1 0.11 13.4 0.7 3.9 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EER30041.1 - 7.7e-05 22.5 0.1 4.8 7.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat STI1 PF17830.1 EER30041.1 - 0.00011 22.1 11.4 0.00068 19.5 6.6 2.7 3 0 0 3 3 3 1 STI1 domain TPR_10 PF13374.6 EER30041.1 - 0.004 17.0 4.2 1.4 8.9 0.4 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat XPC-binding PF09280.11 EER30041.1 - 0.0076 16.0 3.2 0.0092 15.7 1.8 1.8 2 0 0 2 2 2 1 XPC-binding domain TPR_9 PF13371.6 EER30041.1 - 0.01 16.0 0.2 0.032 14.4 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat GerD PF17898.1 EER30041.1 - 0.4 10.6 1.9 3.9 7.5 0.5 2.7 3 0 0 3 3 3 0 Spore germination GerD central core domain TPR_6 PF13174.6 EER30041.1 - 0.64 10.8 3.7 4.6 8.1 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.15 EER30042.1 - 5.7e-36 123.8 1.0 1.1e-35 123.0 0.0 2.0 3 0 0 3 3 3 1 Tim44-like domain Med7 PF05983.11 EER30042.1 - 0.061 13.4 3.8 0.12 12.4 3.8 1.5 1 0 0 1 1 1 0 MED7 protein Molybdopterin_N PF18364.1 EER30042.1 - 0.2 11.7 0.4 0.53 10.3 0.1 1.8 2 0 0 2 2 2 0 Molybdopterin oxidoreductase N-terminal domain Ribosomal_S11 PF00411.19 EER30043.1 - 8.8e-07 29.3 0.0 1.3e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 VPS9 PF02204.18 EER30044.1 - 5.2e-18 65.2 0.0 1.2e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EER30044.1 - 2.8e-16 59.3 0.3 1.1e-14 54.3 0.0 3.6 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EER30044.1 - 7.8e-11 42.4 0.0 0.0006 20.3 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER30044.1 - 0.00026 21.5 0.1 0.23 12.1 0.0 4.3 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER30044.1 - 0.00031 21.0 0.5 0.72 10.6 0.0 5.2 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EER30044.1 - 0.00031 21.1 1.2 5 7.8 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat PX PF00787.24 EER30044.1 - 0.0017 18.3 0.3 0.0046 16.9 0.3 1.7 1 0 0 1 1 1 1 PX domain Phage_holin_2_4 PF16082.5 EER30045.1 - 0.0041 16.8 0.1 0.0074 16.0 0.1 1.4 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like FDF PF09532.10 EER30045.1 - 7.4 7.5 10.2 4.6e+02 1.8 10.0 3.2 1 1 0 1 1 1 0 FDF domain Macoilin PF09726.9 EER30045.1 - 8.5 4.8 7.3 17 3.8 7.3 1.5 1 0 0 1 1 1 0 Macoilin family Inhibitor_I78 PF11720.8 EER30046.1 - 6.9e-09 35.6 0.0 1.8e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EER30046.1 - 0.00061 20.4 0.5 0.0013 19.3 0.5 1.6 1 0 0 1 1 1 1 Potato inhibitor I family MazG_C PF18722.1 EER30046.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 MazG C-terminal domain Nefa_Nip30_N PF10187.9 EER30047.1 - 5.8e-33 113.4 11.1 5.8e-33 113.4 11.1 1.7 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 ImcF-related_N PF14331.6 EER30047.1 - 0.48 9.7 5.1 2.8 7.2 5.1 1.9 1 1 0 1 1 1 0 ImcF-related N-terminal domain APH PF01636.23 EER30048.1 - 1.3e-05 25.3 0.1 3.3e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ank_2 PF12796.7 EER30051.1 - 8.3e-36 122.4 4.3 7.4e-12 45.7 0.1 4.4 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EER30051.1 - 2e-21 76.1 2.1 4.9e-07 30.2 0.2 5.8 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EER30051.1 - 1.6e-19 69.7 2.2 0.0017 18.6 0.1 6.1 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EER30051.1 - 5.9e-19 66.2 5.3 0.011 16.2 0.0 8.4 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 EER30051.1 - 2.5e-18 65.6 15.4 0.00023 21.5 1.2 6.8 6 1 0 6 6 6 4 Ankyrin repeat F-box-like PF12937.7 EER30051.1 - 0.068 13.1 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 F-box-like Peptidase_S8 PF00082.22 EER30052.1 - 2.5e-32 112.3 9.8 6.2e-32 111.1 9.8 1.7 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EER30052.1 - 9.6e-17 61.4 0.2 2.7e-16 60.0 0.2 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.22 EER30053.1 - 7.6e-31 107.5 5.3 1.5e-30 106.5 4.0 2.0 2 1 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.16 EER30053.1 - 4.3e-15 56.2 0.1 7.8e-15 55.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 CK_II_beta PF01214.18 EER30055.1 - 5.1e-76 254.5 0.1 7.3e-76 254.0 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Uso1_p115_C PF04871.13 EER30055.1 - 0.0038 17.6 8.3 0.0071 16.7 8.3 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Utp14 PF04615.13 EER30055.1 - 1.6 7.2 7.0 2.3 6.7 7.0 1.1 1 0 0 1 1 1 0 Utp14 protein ADH_N PF08240.12 EER30056.1 - 6.5e-07 29.2 0.0 8.8e-06 25.6 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EER30056.1 - 0.00029 20.8 0.1 0.0006 19.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EER30056.1 - 0.077 14.0 0.1 0.4 11.7 0.1 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase E1-E2_ATPase PF00122.20 EER30057.1 - 7.6e-47 159.2 8.2 7.7e-47 159.2 2.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EER30057.1 - 8e-25 88.4 0.5 2.6e-24 86.7 0.4 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EER30057.1 - 3e-07 30.8 0.0 8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EER30057.1 - 0.012 15.4 0.2 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.8 EER30058.1 - 4.5e-13 48.8 0.0 5.9e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EER30058.1 - 4.1e-07 30.0 11.9 7.9e-07 29.1 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 EER30059.1 - 0.00017 21.5 0.5 0.0026 17.6 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.8 EER30059.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Thioesterase PF00975.20 EER30059.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 EER30059.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EER30059.1 - 0.024 15.3 0.1 0.03 14.9 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 EER30059.1 - 0.086 12.2 0.0 0.2 10.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 EER30059.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Rep_fac_C PF08542.11 EER30059.1 - 0.18 12.2 0.0 2.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Replication factor C C-terminal domain HTH_Tnp_Tc5 PF03221.16 EER30060.1 - 1e-11 44.7 0.0 2.3e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EER30060.1 - 1.5e-05 24.6 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 EER30060.1 - 0.032 14.4 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain JAB PF01398.21 EER30061.1 - 1.4e-07 31.5 0.2 8e-06 25.8 0.2 2.5 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HMG_box PF00505.19 EER30063.1 - 2.1e-09 37.7 0.5 2.1e-09 37.7 0.5 3.2 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EER30063.1 - 7.2e-05 23.3 0.5 7.2e-05 23.3 0.5 3.4 3 1 1 4 4 4 1 HMG-box domain Xylo_C PF12529.8 EER30063.1 - 0.15 11.6 2.4 0.62 9.6 0.3 2.4 2 0 0 2 2 2 0 Xylosyltransferase C terminal GREB1 PF15782.5 EER30063.1 - 0.58 7.2 5.8 0.67 7.0 0.0 2.0 2 0 0 2 2 2 0 Gene regulated by oestrogen in breast cancer Menin PF05053.13 EER30063.1 - 0.81 8.0 7.5 0.36 9.1 5.0 1.5 1 1 1 2 2 2 0 Menin TFIIE-A_C PF11521.8 EER30063.1 - 1.1 9.6 5.5 11 6.5 0.1 2.9 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha DEAD PF00270.29 EER30064.1 - 1.6e-50 171.3 0.0 4.2e-50 169.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EER30064.1 - 1.3e-26 93.1 0.0 4.9e-26 91.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EER30064.1 - 0.0012 18.8 0.0 0.0075 16.3 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit WLM PF08325.10 EER30065.1 - 0.0048 17.0 2.3 0.0056 16.8 0.1 1.8 1 1 1 2 2 2 1 WLM domain zf-C2H2 PF00096.26 EER30066.1 - 1.2e-16 60.1 34.9 1.2e-07 31.8 2.3 7.2 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EER30066.1 - 4.1e-14 52.3 26.1 5.9e-08 32.8 2.3 5.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EER30066.1 - 1e-09 38.4 7.6 3.1e-05 24.4 1.5 7.9 8 1 1 9 9 9 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EER30066.1 - 1.4e-09 38.0 8.9 0.0021 18.3 0.0 5.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EER30066.1 - 3.6e-09 36.7 6.3 0.0042 17.4 0.0 5.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EER30066.1 - 5.1e-08 32.7 7.6 0.0049 16.8 0.3 4.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EER30066.1 - 6.7e-06 25.8 10.8 0.037 13.8 0.1 4.3 4 0 0 4 4 4 2 zinc-finger C2H2-type zf_ZIC PF18366.1 EER30066.1 - 0.0022 18.0 1.8 1.1 9.5 0.0 3.0 2 0 0 2 2 2 2 Zic proteins zinc finger domain zf_UBZ PF18439.1 EER30066.1 - 0.046 13.3 8.4 0.35 10.5 0.2 3.8 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger AMP-binding PF00501.28 EER30068.1 - 1.4e-85 287.5 0.0 1.7e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EER30068.1 - 7.3e-11 42.9 0.1 1.9e-10 41.6 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ret2_MD PF18528.1 EER30068.1 - 0.092 13.1 0.1 0.74 10.2 0.0 2.2 2 0 0 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Kelch_6 PF13964.6 EER30070.1 - 4.1e-06 26.9 2.2 0.071 13.4 0.0 4.2 4 0 0 4 4 4 2 Kelch motif HAT PF02184.16 EER30071.1 - 6.5e-23 80.4 79.9 1.6e-14 53.5 4.7 13.6 15 0 0 15 15 15 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EER30071.1 - 2.6e-21 74.5 32.9 0.014 16.2 0.1 11.7 6 3 7 13 13 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 EER30071.1 - 3.1e-21 75.6 0.0 0.0006 20.3 0.0 7.7 6 1 0 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 EER30071.1 - 1e-15 58.5 24.4 0.00037 20.6 1.3 6.6 2 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EER30071.1 - 9.1e-07 28.8 3.4 5.6 7.6 0.0 7.0 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EER30071.1 - 2.7e-06 27.9 7.1 4.8 7.9 0.0 7.4 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 EER30071.1 - 1.4e-05 24.9 14.9 3.7 7.9 0.0 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_15 PF13429.6 EER30071.1 - 2.6e-05 23.6 15.8 0.85 8.8 0.1 5.7 2 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EER30071.1 - 0.00012 22.0 4.1 17 6.0 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 EER30071.1 - 0.00021 21.3 30.5 0.076 13.1 1.3 7.8 6 2 2 8 8 8 2 U3 small nucleolar RNA-associated protein 6 TPR_6 PF13174.6 EER30071.1 - 0.00047 20.6 15.7 13 6.7 0.0 8.1 7 1 1 8 8 8 0 Tetratricopeptide repeat NRDE-2 PF08424.10 EER30071.1 - 0.0072 15.5 27.0 0.05 12.7 0.1 6.2 4 3 3 7 7 7 3 NRDE-2, necessary for RNA interference SNase PF00565.17 EER30071.1 - 0.028 14.9 1.4 0.5 10.9 0.2 2.8 3 0 0 3 3 2 0 Staphylococcal nuclease homologue NifW PF03206.14 EER30071.1 - 2.8 8.5 6.6 34 5.0 0.1 4.5 5 0 0 5 5 4 0 Nitrogen fixation protein NifW TPR_12 PF13424.6 EER30071.1 - 6.9 7.0 21.3 19 5.6 0.0 8.0 9 2 0 9 9 9 0 Tetratricopeptide repeat Nop PF01798.18 EER30072.1 - 1.1e-72 244.2 0.0 1.6e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EER30072.1 - 1e-46 158.7 1.8 2.2e-46 157.7 1.8 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain Spore_YtrH PF14034.6 EER30072.1 - 0.024 14.8 0.1 0.13 12.5 0.1 2.3 3 0 0 3 3 3 0 Sporulation protein YtrH AdoHcyase PF05221.17 EER30073.1 - 2.6e-129 430.7 0.0 2.7e-74 250.0 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EER30073.1 - 3.2e-83 277.7 1.5 5.3e-83 276.9 1.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EER30073.1 - 8.7e-07 28.5 0.1 1.8e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EER30073.1 - 0.0029 17.2 0.1 0.0051 16.4 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EER30073.1 - 0.0076 16.5 0.1 0.019 15.2 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 EER30073.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase zf-H2C2_2 PF13465.6 EER30074.1 - 3e-07 30.6 13.4 3.5e-07 30.4 1.1 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EER30074.1 - 6e-07 29.3 2.4 0.0097 15.9 0.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EER30074.1 - 4.7e-06 26.8 0.8 4.7e-06 26.8 0.8 3.9 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EER30074.1 - 1.6e-05 25.4 5.5 0.00049 20.7 0.6 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger FOXP-CC PF16159.5 EER30074.1 - 0.0068 17.0 15.5 0.11 13.1 0.1 3.7 3 1 2 5 5 5 2 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 EER30074.1 - 0.033 14.0 1.1 0.073 12.8 0.1 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 EER30074.1 - 0.058 13.2 3.4 0.27 11.0 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Sina PF03145.16 EER30074.1 - 5.8 6.8 9.6 16 5.4 0.8 2.2 1 1 1 2 2 2 0 Seven in absentia protein family Zap1_zf2 PF18217.1 EER30074.1 - 6.2 6.9 14.1 6.1 6.9 1.2 2.7 2 1 0 2 2 2 0 Zap1 zinc finger 2 zf-C2H2_jaz PF12171.8 EER30074.1 - 8.7 6.8 8.6 1.6 9.1 0.3 3.5 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.23 EER30075.1 - 9.5e-57 192.3 0.0 1.5e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EER30075.1 - 6.5e-24 83.6 1.9 4.9e-14 52.0 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 EER30075.1 - 1e-22 80.3 0.2 5.5e-21 74.8 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EER30075.1 - 2.2e-18 66.6 0.0 7.8e-18 64.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EER30075.1 - 1.3e-07 31.2 0.0 4.2e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 EER30075.1 - 2.2e-07 31.2 18.1 3e-05 24.3 0.2 4.4 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 EER30075.1 - 6.2e-06 26.3 0.0 0.00042 20.4 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 EER30075.1 - 0.0032 17.5 0.1 0.13 12.3 0.0 3.6 3 1 1 4 4 4 1 SLIDE CHDCT2 PF08074.11 EER30075.1 - 0.013 15.7 3.2 0.064 13.4 0.0 3.2 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain ABC_tran PF00005.27 EER30076.1 - 1.5e-36 125.9 0.0 2.3e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EER30076.1 - 3.2e-11 43.6 5.7 0.013 15.4 0.0 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EER30076.1 - 6.8e-11 42.0 4.9 0.0013 18.2 0.1 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EER30076.1 - 1.4e-05 25.0 0.1 0.19 11.4 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain Rad17 PF03215.15 EER30076.1 - 4e-05 23.6 0.1 0.024 14.6 0.0 2.6 2 1 1 3 3 3 1 Rad17 P-loop domain AAA PF00004.29 EER30076.1 - 7.2e-05 23.2 0.1 0.087 13.2 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EER30076.1 - 0.00018 21.8 0.4 0.053 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EER30076.1 - 0.00037 20.9 0.0 0.11 12.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EER30076.1 - 0.00072 19.5 0.9 0.65 9.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_24 PF13479.6 EER30076.1 - 0.00082 19.1 1.4 0.097 12.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EER30076.1 - 0.0013 19.3 0.0 2.7 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.6 EER30076.1 - 0.0013 17.5 0.0 0.0013 17.5 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EER30076.1 - 0.0019 17.8 0.7 0.026 14.0 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EER30076.1 - 0.0023 18.3 0.1 1.4 9.3 0.1 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.6 EER30076.1 - 0.0034 17.5 0.2 1.1 9.4 0.2 2.8 3 0 0 3 3 2 1 AAA domain DLIC PF05783.11 EER30076.1 - 0.0036 16.2 0.0 0.0062 15.4 0.0 1.3 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) SRP54 PF00448.22 EER30076.1 - 0.0061 16.2 3.9 0.11 12.1 0.2 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EER30076.1 - 0.007 16.1 1.2 2.7 7.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EER30076.1 - 0.012 15.4 0.9 0.84 9.3 0.1 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EER30076.1 - 0.017 14.3 0.6 1.3 8.1 0.0 2.8 3 1 1 4 4 4 0 NB-ARC domain AAA_28 PF13521.6 EER30076.1 - 0.019 15.2 0.1 4 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EER30076.1 - 0.031 14.2 2.9 1.3 8.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 EER30076.1 - 0.035 13.8 1.2 9.1 5.9 0.0 3.0 3 0 0 3 3 3 0 Thymidylate kinase TsaE PF02367.17 EER30076.1 - 0.049 13.6 1.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EER30076.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 EER30076.1 - 0.098 12.7 0.2 8.8 6.3 0.1 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) VirE PF05272.11 EER30076.1 - 0.12 12.1 0.0 6.9 6.3 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E Rad51 PF08423.11 EER30076.1 - 0.14 11.4 0.2 1.1 8.5 0.1 2.0 2 0 0 2 2 2 0 Rad51 MMR_HSR1 PF01926.23 EER30076.1 - 0.16 12.1 0.6 28 4.8 0.4 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EER30076.1 - 0.2 12.1 5.9 1 9.8 0.2 2.6 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EER30076.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EER30076.1 - 1.2 9.2 3.5 13 5.8 0.1 3.2 3 2 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 EER30076.1 - 1.3 8.9 3.7 17 5.3 0.2 2.9 3 0 0 3 3 3 0 NTPase FF PF01846.19 EER30077.1 - 3.2e-43 145.7 18.0 2.3e-14 53.3 0.2 6.9 6 1 0 6 6 6 5 FF domain WW PF00397.26 EER30077.1 - 1.1e-16 60.6 11.5 5.2e-08 32.9 0.2 2.7 2 0 0 2 2 2 2 WW domain DNA_pol_P_Exo PF18049.1 EER30077.1 - 0.074 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo Glyco_hyd_101C PF17451.2 EER30077.1 - 3.2 8.0 7.2 14 6.0 0.2 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain Trs65 PF12735.7 EER30078.1 - 3.6e-78 263.2 0.0 7.8e-78 262.1 0.0 1.6 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 EER30079.1 - 5.6e-19 68.1 0.1 5.6e-19 68.1 0.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family DAD PF02109.16 EER30079.1 - 0.062 13.6 0.2 1.2 9.4 0.1 2.5 2 1 0 2 2 2 0 DAD family DSS1_SEM1 PF05160.13 EER30080.1 - 1.7e-19 69.6 13.3 2.1e-19 69.3 13.3 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Iwr1 PF08574.10 EER30080.1 - 0.13 13.2 5.6 7 7.7 1.9 2.1 2 0 0 2 2 2 0 Transcription factor Iwr1 PGK PF00162.19 EER30081.1 - 6.8e-151 502.5 0.6 7.7e-151 502.3 0.6 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.8 EER30081.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Coccidioides_posadasii_C735_delta_SOWgp-JCVI-cpa1-1.0/GCA_000151335.1_JCVI-cpa1-1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Coccidioides_posadasii_C735_delta_SOWgp-JCVI-cpa1-1.0/GCA_000151335.1_JCVI-cpa1-1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Coccidioides_posadasii_C735_delta_SOWgp-JCVI-cpa1-1.0/GCA_000151335.1_JCVI-cpa1-1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Coccidioides_posadasii_C735_delta_SOWgp-JCVI-cpa1-1.0/GCA_000151335.1_JCVI-cpa1-1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 16:50:48 2019 # [ok]