# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- SNF2_N PF00176.18 EER22853.1 - 3.1e-20 72.1 0.1 5.4e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER22853.1 - 0.0019 18.0 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dynamin_N PF00350.18 EER22855.1 - 1.4e-30 106.3 0.5 2.8e-30 105.3 0.1 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EER22855.1 - 1.4e-14 53.6 0.1 1.7e-12 46.7 0.0 2.9 3 0 0 3 3 3 1 Dynamin central region MMR_HSR1 PF01926.18 EER22855.1 - 9.1e-06 25.6 0.0 4.5e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EER22855.1 - 0.0008 18.8 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EER22855.1 - 0.0022 18.3 0.1 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EER22855.1 - 0.0037 17.2 0.3 0.44 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EER22855.1 - 0.0041 17.6 0.0 0.014 15.9 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein PRK PF00485.13 EER22855.1 - 0.011 15.2 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Trp_dioxygenase PF03301.8 EER22855.1 - 0.031 13.3 0.7 0.052 12.6 0.5 1.2 1 0 0 1 1 1 0 Tryptophan 2,3-dioxygenase DUF3435 PF11917.3 EER22856.1 - 5.4e-66 223.0 0.1 5.2e-58 196.7 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3435) DUF2462 PF09495.5 EER22856.1 - 0.034 14.8 0.0 0.06 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) OmpH PF03938.9 EER22856.1 - 0.14 12.1 0.2 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IMS PF00817.15 EER22857.1 - 3.3e-43 147.0 0.9 7.4e-43 145.8 0.6 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EER22857.1 - 2.5e-17 63.0 0.1 5.6e-17 61.8 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EER22857.1 - 1.4e-06 28.0 0.0 4.2e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif VPS28 PF03997.7 EER22857.1 - 0.095 12.2 1.7 0.15 11.6 0.2 2.0 2 0 0 2 2 2 0 VPS28 protein A_thal_3526 PF09713.5 EER22857.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) FHA PF00498.21 EER22858.1 - 7.6e-06 25.9 0.2 1.7e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 EER22858.1 - 7.4e-05 22.8 0.1 0.0033 17.5 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Sugar_tr PF00083.19 EER22859.1 - 3.6e-73 246.6 27.4 4.2e-73 246.4 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER22859.1 - 3.1e-17 62.3 59.7 5.9e-13 48.2 20.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.8 EER22860.1 - 1.4e-09 37.8 0.5 2.2e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 Putative cyclase Methyltransf_28 PF02636.12 EER22860.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Acetyltransf_1 PF00583.19 EER22861.1 - 5.6e-09 35.9 0.7 8.7e-09 35.3 0.5 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EER22861.1 - 1.6e-07 31.4 0.0 3.4e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER22861.1 - 6.3e-06 26.2 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER22861.1 - 8.4e-06 25.6 0.0 2.4e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER22861.1 - 0.0088 15.7 0.0 0.024 14.3 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein Ferritin_2 PF13668.1 EER22862.1 - 6.2e-07 29.4 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Sugar_tr PF00083.19 EER22863.1 - 9.2e-20 70.6 23.8 7.2e-18 64.3 16.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter SR-25 PF10500.4 EER22864.1 - 0.13 11.6 7.9 0.21 11.0 5.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AMP-binding PF00501.23 EER22865.1 - 7e-75 251.9 0.0 8.4e-75 251.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER22865.1 - 3.7e-12 47.0 0.5 6.6e-12 46.2 0.4 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EER22866.1 - 8.1e-39 133.3 25.9 1.4e-38 132.5 17.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily CoA_binding_2 PF13380.1 EER22867.1 - 1.9e-27 95.7 0.0 2.4e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Rad4 PF03835.10 EER22869.1 - 2.5e-29 101.5 0.4 7.9e-29 99.9 0.0 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EER22869.1 - 1.1e-28 98.7 0.2 2e-28 97.8 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.4 EER22869.1 - 5.8e-18 64.9 0.0 2.2e-17 63.1 0.0 2.1 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.4 EER22869.1 - 1.6e-16 59.5 0.0 3.7e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.14 EER22869.1 - 0.015 15.5 0.0 0.044 13.9 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily HIT PF01230.18 EER22870.1 - 4.2e-24 84.9 0.1 7.8e-24 84.0 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EER22870.1 - 3.9e-06 27.0 0.0 6.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EER22870.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 HD_3 PF13023.1 EER22871.1 - 7.4e-49 165.6 0.2 9.3e-49 165.3 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EER22871.1 - 0.012 15.6 0.2 0.034 14.1 0.1 1.8 1 1 1 2 2 2 0 HD domain HAUS6_N PF14661.1 EER22872.1 - 4.6e-23 81.8 0.0 4.6e-23 81.8 0.0 2.4 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus cobW PF02492.14 EER22873.1 - 2.3e-44 150.9 0.0 3.2e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EER22873.1 - 3.7e-05 24.0 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EER22873.1 - 0.00087 19.0 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EER22873.1 - 0.0025 17.9 0.1 0.034 14.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Septin PF00735.13 EER22873.1 - 0.003 16.6 0.1 1 8.3 0.0 2.1 2 0 0 2 2 2 2 Septin MMR_HSR1 PF01926.18 EER22873.1 - 0.011 15.6 0.2 0.037 13.9 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EER22873.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EER22873.1 - 0.012 15.0 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 EER22873.1 - 0.022 14.4 0.0 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain ArgK PF03308.11 EER22873.1 - 0.022 13.5 0.1 1.4 7.6 0.0 2.5 3 0 0 3 3 3 0 ArgK protein MobB PF03205.9 EER22873.1 - 0.023 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EER22873.1 - 0.031 14.1 0.0 0.09 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EER22873.1 - 0.036 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EER22873.1 - 0.039 14.2 0.0 0.095 13.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 EER22873.1 - 0.039 12.8 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EER22873.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain ThuA PF06283.6 EER22873.1 - 0.059 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Trehalose utilisation AAA_10 PF12846.2 EER22873.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Viral_helicase1 PF01443.13 EER22873.1 - 0.092 12.2 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 EER22873.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EER22873.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mob1_phocein PF03637.12 EER22874.1 - 7.3e-25 87.6 0.1 1.1e-24 87.0 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Pkinase PF00069.20 EER22875.1 - 1.7e-12 47.0 0.1 1.5e-10 40.6 0.1 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER22875.1 - 9e-09 34.7 0.0 9e-08 31.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER22875.1 - 0.058 12.3 0.0 0.16 10.8 0.0 1.6 1 1 0 1 1 1 0 Kinase-like Lon_C PF05362.8 EER22876.1 - 4.3e-62 209.0 0.0 9.9e-62 207.8 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EER22876.1 - 7.6e-39 133.5 0.3 7.6e-39 133.5 0.2 2.2 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EER22876.1 - 4.1e-22 78.7 0.0 9.9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EER22876.1 - 1.3e-06 28.2 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EER22876.1 - 1.7e-06 28.0 0.0 4.9e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EER22876.1 - 5.5e-06 25.8 0.0 1.5e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 EER22876.1 - 1.7e-05 24.9 0.1 0.00032 20.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EER22876.1 - 2.6e-05 23.0 0.2 6.2e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.1 EER22876.1 - 3.8e-05 23.7 0.2 0.00077 19.5 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EER22876.1 - 5.3e-05 24.0 0.1 0.00036 21.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EER22876.1 - 0.00012 21.2 0.0 0.0013 17.8 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EER22876.1 - 0.0062 16.4 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EER22876.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.17 EER22876.1 - 0.027 14.3 0.6 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase AAA_18 PF13238.1 EER22876.1 - 0.03 14.6 0.0 0.03 14.6 0.0 3.2 4 0 0 4 4 2 0 AAA domain IstB_IS21 PF01695.12 EER22876.1 - 0.039 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EER22876.1 - 0.042 13.0 0.0 0.093 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EER22876.1 - 0.061 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab PF00006.20 EER22876.1 - 0.067 12.6 0.1 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EER22876.1 - 0.07 12.5 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Phage_connect_1 PF05135.8 EER22876.1 - 0.11 12.6 1.2 6.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein AAA_33 PF13671.1 EER22876.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EER22876.1 - 0.2 10.3 4.9 0.99 8.0 0.0 2.9 3 0 0 3 3 3 0 TIP49 C-terminus ABC_tran PF00005.22 EER22876.1 - 1.5 9.1 5.3 0.69 10.2 0.0 2.8 3 0 0 3 3 3 0 ABC transporter CTDII PF01556.13 EER22877.1 - 3.7e-29 100.4 1.2 9.1e-22 76.7 0.2 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EER22877.1 - 3.1e-23 81.2 6.1 4.4e-23 80.7 2.3 2.2 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EER22877.1 - 9.2e-11 41.6 19.2 9.2e-11 41.6 13.3 2.4 2 0 0 2 2 2 1 DnaJ central domain HypA PF01155.14 EER22877.1 - 6.9 6.3 11.7 1.5 8.5 0.7 2.8 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family BRO1 PF03097.13 EER22878.1 - 7.1e-129 429.8 0.0 7.1e-129 429.8 0.0 2.4 3 1 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EER22878.1 - 5.3e-99 330.9 12.8 9.6e-99 330.0 8.9 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF148 PF02520.12 EER22878.1 - 5.6 6.7 12.6 0.097 12.4 1.5 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF148 SAP30_Sin3_bdg PF13867.1 EER22879.1 - 4.1e-15 55.3 0.1 1.4e-14 53.7 0.0 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-H2C2_2 PF13465.1 EER22880.1 - 3.3e-10 39.7 17.1 2.4e-06 27.5 2.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EER22880.1 - 8.1e-08 32.1 13.5 0.0017 18.5 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER22880.1 - 0.0058 16.8 1.5 0.0058 16.8 1.0 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EER22880.1 - 0.16 12.1 2.9 0.41 10.8 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EER22880.1 - 0.18 11.7 2.1 8.2 6.4 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger MOSC PF03473.12 EER22881.1 - 6.4e-13 48.3 0.2 2.5e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 MOSC domain MOSC_N PF03476.11 EER22881.1 - 1.2e-06 28.2 0.0 2.7e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain AAA_25 PF13481.1 EER22882.1 - 3.9e-07 29.6 0.7 6.3e-05 22.4 0.5 2.8 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 EER22882.1 - 8.8e-06 24.7 0.0 0.0014 17.5 0.0 2.8 1 1 0 1 1 1 1 Rad51 RecA PF00154.16 EER22882.1 - 1.3e-05 24.4 0.0 3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EER22882.1 - 0.0062 15.6 0.0 0.022 13.9 0.0 1.9 2 0 0 2 2 2 1 KaiC IstB_IS21 PF01695.12 EER22882.1 - 0.0066 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EER22882.1 - 0.013 15.4 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EER22882.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EER22882.1 - 0.028 14.1 0.0 0.071 12.8 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EER22882.1 - 0.03 14.3 0.1 0.047 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EER22882.1 - 0.055 13.6 0.0 0.23 11.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EER22882.1 - 0.081 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EER22882.1 - 0.092 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EER22882.1 - 0.11 12.3 0.1 0.22 11.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EER22882.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein FA_desaturase PF00487.19 EER22883.1 - 7.6e-19 68.1 10.8 7.6e-19 68.1 7.5 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EER22883.1 - 6.6e-17 61.0 0.1 1.5e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Peptidase_M3 PF01432.15 EER22884.1 - 8.2e-163 542.6 0.1 1.3e-162 542.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EER22884.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Effector protein DTHCT PF08070.6 EER22885.1 - 0.43 11.2 11.2 8.3 7.1 2.8 2.6 1 1 1 2 2 2 0 DTHCT (NUC029) region CDC45 PF02724.9 EER22885.1 - 0.52 8.2 5.9 0.54 8.2 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3408 PF11888.3 EER22885.1 - 2.9 7.8 8.8 1.2 9.0 4.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) EF-hand_7 PF13499.1 EER22886.1 - 3.2e-14 52.7 0.1 4.5e-10 39.5 0.1 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EER22886.1 - 2.2e-11 42.6 0.4 0.0022 17.7 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 EER22886.1 - 1.2e-09 37.9 0.0 0.00011 22.0 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EER22886.1 - 2.7e-09 35.6 0.2 0.018 14.3 0.0 3.9 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EER22886.1 - 4.8e-06 26.1 0.5 0.00078 19.0 0.1 3.3 2 2 1 3 3 3 1 EF-hand domain pair PAXIP1_C PF15364.1 EER22886.1 - 0.0062 16.4 1.6 0.14 12.0 1.4 2.1 2 0 0 2 2 2 1 PAXIP1-associated-protein-1 C term PTIP binding protein UPF0154 PF03672.8 EER22886.1 - 0.057 13.0 0.0 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 EER22886.1 - 0.063 12.6 2.0 2.9 7.4 0.7 3.3 3 0 0 3 3 3 0 EF hand DUF3216 PF11505.3 EER22886.1 - 0.072 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Fungal_trans PF04082.13 EER22887.1 - 5.4e-66 222.1 0.0 8.2e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EER22887.1 - 3.9e-05 23.7 13.5 0.0017 18.5 2.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER22887.1 - 0.00044 20.3 13.8 0.0022 18.1 1.8 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EER22887.1 - 0.015 15.5 10.5 0.21 11.9 2.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Xpo1 PF08389.7 EER22888.1 - 4.9e-27 94.6 1.9 2.2e-26 92.5 0.3 3.0 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EER22888.1 - 3.4e-06 26.8 0.3 3.9e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EER22888.1 - 0.00054 20.2 0.2 0.052 13.8 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 EER22888.1 - 0.0015 18.9 0.4 0.32 11.5 0.0 5.0 6 1 0 6 6 6 1 HEAT-like repeat HEAT PF02985.17 EER22888.1 - 0.0036 17.2 0.3 9.6 6.5 0.0 4.9 4 1 0 4 4 4 1 HEAT repeat LSM PF01423.17 EER22889.1 - 1.9e-15 56.1 0.2 2.3e-15 55.8 0.1 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EER22889.1 - 0.096 12.1 0.0 0.46 9.9 0.0 1.9 2 0 0 2 2 2 0 PhnA protein 5-FTHF_cyc-lig PF01812.15 EER22890.1 - 2.4e-19 69.8 0.0 2.7e-17 63.1 0.0 2.3 2 1 0 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 EER22891.1 - 4.5e-92 307.1 0.0 5.2e-92 307.0 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.5 EER22892.1 - 7.3e-22 77.7 1.1 8.4e-22 77.5 0.8 1.1 1 0 0 1 1 1 1 Yqey-like protein Cache_2 PF08269.6 EER22892.1 - 0.1 12.5 0.4 0.23 11.4 0.3 1.6 1 0 0 1 1 1 0 Cache domain FliG_C PF01706.11 EER22892.1 - 0.25 11.3 1.8 0.69 9.9 0.1 2.1 2 0 0 2 2 2 0 FliG C-terminal domain Nucleoporin_C PF03177.9 EER22893.1 - 4.1e-137 458.2 6.1 5.3e-137 457.8 4.2 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EER22893.1 - 1.1e-85 287.9 0.1 1.6e-85 287.4 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like TIP120 PF08623.5 EER22893.1 - 0.067 12.7 0.0 14 5.2 0.0 2.7 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) DUF619 PF04768.8 EER22894.1 - 3e-51 173.1 0.0 9.1e-51 171.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Arv1 PF04161.8 EER22895.1 - 1.9e-39 135.7 0.1 2.5e-33 115.7 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family ATP_synt_H PF05493.8 EER22896.1 - 1.9e-26 91.8 3.8 2.1e-26 91.7 2.6 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF1129 PF06570.6 EER22896.1 - 0.0088 15.3 0.5 0.011 15.1 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Pox_A14 PF05767.7 EER22896.1 - 0.045 13.7 0.2 0.049 13.5 0.1 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Polysacc_synt_C PF14667.1 EER22896.1 - 0.048 13.4 0.5 0.064 13.0 0.4 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Claudin_2 PF13903.1 EER22896.1 - 0.064 12.9 0.7 0.072 12.7 0.5 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 EER22896.1 - 0.18 11.2 2.3 0.19 11.1 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) YfhO PF09586.5 EER22896.1 - 0.23 9.4 0.7 0.25 9.3 0.5 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FixQ PF05545.6 EER22896.1 - 0.29 10.8 5.5 0.079 12.6 1.2 1.9 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Dabb PF07876.7 EER22897.1 - 5.5e-16 58.7 0.2 6.4e-16 58.5 0.2 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4167 PF13763.1 EER22897.1 - 0.057 13.4 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) BAR_2 PF10455.4 EER22898.1 - 1.3e-63 214.6 0.2 1.8e-63 214.1 0.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EER22898.1 - 1.6e-19 70.3 3.4 2.6e-18 66.3 2.3 2.0 1 1 0 1 1 1 1 BAR domain Mod_r PF07200.8 EER22898.1 - 0.011 15.7 2.7 0.011 15.6 0.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein zf-C4H2 PF10146.4 EER22898.1 - 0.012 15.5 1.0 0.012 15.5 0.7 2.0 2 1 0 2 2 2 0 Zinc finger-containing protein Arfaptin PF06456.8 EER22898.1 - 0.032 13.5 1.4 0.093 12.0 0.2 2.2 2 1 0 2 2 2 0 Arfaptin-like domain HSCB_C PF07743.8 EER22898.1 - 1.8 9.1 4.8 16 6.0 0.5 3.0 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain APH PF01636.18 EER22899.1 - 1.9e-05 24.5 4.2 5.4e-05 23.0 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EER22899.1 - 0.00064 18.9 0.0 0.0017 17.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EER22899.1 - 0.0013 17.8 0.0 0.0034 16.4 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EER22899.1 - 0.092 12.5 0.0 0.37 10.6 0.0 2.0 1 1 1 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Borrelia_P83 PF05262.6 EER22899.1 - 6.6 4.8 8.6 12 4.0 5.9 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein Methyltransf_8 PF05148.10 EER22902.1 - 8.6e-52 175.9 0.1 1.4e-49 168.6 0.0 2.8 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EER22902.1 - 1.8e-06 28.3 1.0 7.4e-06 26.3 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER22902.1 - 0.031 14.6 0.0 2.3 8.6 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain MAP65_ASE1 PF03999.7 EER22902.1 - 6.9 5.1 21.0 11 4.4 14.6 1.2 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Proteasome PF00227.21 EER22903.1 - 9.7e-57 191.3 0.1 1.2e-56 190.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EER22903.1 - 9.5e-14 50.4 0.2 2.2e-13 49.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 EER22904.1 - 6.7e-137 457.0 0.5 9e-137 456.6 0.3 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family CT47 PF15623.1 EER22905.1 - 0.28 10.8 10.0 0.39 10.4 6.9 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Methyltransf_23 PF13489.1 EER22906.1 - 4.4e-11 42.7 0.0 6.4e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER22906.1 - 9.8e-10 38.8 0.0 1.9e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER22906.1 - 2e-07 31.3 0.0 4.5e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER22906.1 - 1.2e-05 24.9 0.0 0.00018 21.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER22906.1 - 1.6e-05 25.4 0.1 9.1e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER22906.1 - 0.00052 20.3 0.0 0.0016 18.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER22906.1 - 0.0046 16.9 0.0 0.016 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EER22906.1 - 0.0057 15.7 0.0 0.0098 15.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EER22906.1 - 0.0095 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EER22906.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EER22906.1 - 0.13 11.3 0.0 0.62 9.1 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short PF00106.20 EER22907.1 - 1.3e-21 77.2 0.0 2.1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER22907.1 - 1.4e-13 51.2 0.1 2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER22907.1 - 1e-05 25.2 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EER22907.1 - 0.00037 19.5 0.1 0.00063 18.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EER22907.1 - 0.0079 15.6 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EER22907.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EER22907.1 - 0.092 12.5 0.2 0.22 11.3 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Erg28 PF03694.8 EER22908.1 - 1.2e-40 138.0 0.7 1.4e-40 137.7 0.5 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_tr_C PF02744.12 EER22909.1 - 3.7e-56 189.2 0.1 8.5e-56 188.0 0.1 1.5 1 1 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 EER22909.1 - 3.9e-51 173.7 1.0 4.7e-49 166.9 0.1 2.7 3 1 1 4 4 4 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 EER22909.1 - 4.2e-07 30.4 0.0 1e-06 29.1 0.0 1.6 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EER22909.1 - 0.0017 18.5 0.1 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Cwf_Cwc_15 PF04889.7 EER22909.1 - 0.21 11.2 1.5 0.43 10.2 1.0 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Fungal_trans_2 PF11951.3 EER22910.1 - 2.5e-23 82.3 0.2 7.1e-17 61.0 0.1 3.4 4 0 0 4 4 4 3 Fungal specific transcription factor domain Zn_clus PF00172.13 EER22910.1 - 3.8e-07 29.9 11.9 7.3e-07 29.0 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EER22910.1 - 0.00028 19.8 0.3 0.00093 18.1 0.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Asp_protease PF09668.5 EER22911.1 - 1.2e-58 196.0 0.1 1.8e-58 195.5 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EER22911.1 - 9e-11 42.1 0.1 3.3e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 EER22911.1 - 3.2e-08 32.8 0.0 5.6e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EER22911.1 - 5.5e-08 32.4 0.0 1.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 EER22911.1 - 2.6e-06 27.1 0.0 6.8e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EER22911.1 - 7.3e-06 25.9 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EER22911.1 - 0.00022 21.1 0.0 0.00058 19.7 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.1 EER22911.1 - 0.00052 19.4 0.0 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UN_NPL4 PF11543.3 EER22911.1 - 0.0054 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 NAD_binding_7 PF13241.1 EER22911.1 - 0.08 13.2 0.1 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Acetyltransf_1 PF00583.19 EER22912.1 - 6.7e-12 45.2 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER22912.1 - 2.1e-09 37.3 0.0 3.6e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER22912.1 - 0.00015 21.4 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EER22912.1 - 0.00019 21.2 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER22912.1 - 0.0011 18.7 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EER22912.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EER22912.1 - 0.018 14.9 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER22912.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NOGCT PF08155.6 EER22913.1 - 1.9e-28 97.8 2.8 4.1e-28 96.8 1.9 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EER22913.1 - 4.9e-27 93.5 0.6 1.1e-26 92.4 0.4 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EER22913.1 - 2e-15 56.7 0.0 4.4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EER22913.1 - 6.2e-08 32.0 0.0 1.9e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EER22913.1 - 0.00015 22.2 0.0 0.0006 20.3 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EER22913.1 - 0.0019 18.0 1.0 1.3 8.8 0.0 2.8 2 1 1 3 3 3 2 Dynamin family Gtr1_RagA PF04670.7 EER22913.1 - 0.0066 15.6 0.1 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 EER22913.1 - 0.15 12.4 2.1 9.5 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AATase PF07247.7 EER22914.1 - 1.8e-16 59.7 0.0 4.1e-16 58.6 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EER22914.1 - 1.7e-07 30.4 0.6 0.018 13.9 0.0 2.7 2 1 0 2 2 2 2 Condensation domain E1_DerP2_DerF2 PF02221.10 EER22915.1 - 1.1e-26 93.6 0.2 1.3e-26 93.3 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EER22915.1 - 0.00046 20.2 0.1 0.0012 18.8 0.1 1.7 1 1 0 1 1 1 1 ML-like domain Wzt_C PF14524.1 EER22915.1 - 0.067 12.8 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Wzt C-terminal domain CopC PF04234.7 EER22915.1 - 0.099 13.2 0.0 0.18 12.4 0.0 1.6 1 1 0 1 1 1 0 CopC domain Alph_Pro_TM PF09608.5 EER22915.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) ATP-synt_F PF01990.12 EER22916.1 - 5.3e-31 106.8 0.1 6.1e-31 106.6 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.4 EER22917.1 - 3.4e-35 120.3 0.6 5.9e-35 119.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF4131 PF13567.1 EER22917.1 - 0.21 10.9 2.2 0.64 9.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) MTHFR PF02219.12 EER22919.1 - 8.2e-116 386.0 0.0 1.2e-115 385.5 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF1804 PF08822.6 EER22919.1 - 0.19 11.4 0.1 0.42 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Pribosyltran PF00156.22 EER22920.1 - 5.5e-16 58.4 0.1 1e-15 57.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF3186 PF11382.3 EER22920.1 - 0.059 12.4 0.1 0.075 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Glyco_transf_5 PF08323.6 EER22922.1 - 1.6e-13 50.7 0.0 3.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.19 EER22922.1 - 1.4e-10 41.0 0.3 3.2e-09 36.6 0.2 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.15 EER22922.1 - 5.4e-08 32.4 0.0 1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EER22922.1 - 1.4e-07 31.7 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Aconitase PF00330.15 EER22923.1 - 2.3e-184 613.2 0.0 2.8e-184 612.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EER22923.1 - 2e-43 147.6 0.0 3.8e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glycos_transf_4 PF00953.16 EER22924.1 - 2.7e-34 118.2 12.1 2.7e-34 118.2 8.4 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.27 EER22925.1 - 2.9e-22 77.6 3.9 3.2e-07 29.9 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EER22925.1 - 0.082 12.6 1.0 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term peroxidase PF00141.18 EER22926.1 - 5.5e-51 173.2 0.0 8.8e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase PITH PF06201.8 EER22927.1 - 9.2e-42 142.3 0.0 1.6e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EER22927.1 - 2.7e-25 88.0 0.0 4.9e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EER22927.1 - 1.5e-08 34.6 0.1 5e-08 32.9 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EER22927.1 - 4.5e-06 26.8 0.1 2.1e-05 24.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EER22927.1 - 0.00017 21.5 0.1 0.00034 20.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EER22927.1 - 0.00057 19.4 0.3 0.051 13.1 0.0 2.2 1 1 1 2 2 2 1 Redoxin HyaE PF07449.6 EER22927.1 - 0.0044 16.9 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 EER22927.1 - 0.013 15.2 0.2 0.24 11.1 0.1 2.1 1 1 1 2 2 2 0 AhpC/TSA family zf-C2H2 PF00096.21 EER22928.1 - 3.8e-10 39.4 17.7 4.1e-06 26.8 0.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER22928.1 - 9.1e-10 38.1 10.6 0.00025 21.1 3.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EER22928.1 - 1.5e-07 31.3 13.0 1.1e-06 28.6 3.7 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EER22928.1 - 1.6e-05 24.8 5.3 0.0074 16.3 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EER22928.1 - 8.3e-05 22.6 5.1 0.0029 17.7 0.4 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EER22928.1 - 0.0054 16.6 9.2 0.016 15.0 0.3 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EER22928.1 - 0.5 10.5 3.9 12 6.0 0.2 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EER22928.1 - 6 6.6 6.9 13 5.6 1.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type ATP_bind_4 PF01902.12 EER22929.1 - 6e-17 61.7 0.0 4.6e-05 22.8 0.0 4.3 4 0 0 4 4 4 4 ATP-binding region Ribonuc_L-PSP PF01042.16 EER22929.1 - 6.4e-17 61.4 0.0 1.4e-09 37.7 0.0 3.8 4 0 0 4 4 4 2 Endoribonuclease L-PSP Adeno_E1B_55K_N PF04623.7 EER22929.1 - 0.063 13.7 2.1 0.18 12.3 1.5 1.7 1 0 0 1 1 1 0 Adenovirus E1B protein N-terminus CTP_transf_1 PF01148.15 EER22930.1 - 6.2e-06 26.0 13.6 6.2e-06 26.0 9.4 4.0 3 1 0 3 3 3 1 Cytidylyltransferase family DUF3543 PF12063.3 EER22931.1 - 2.3e-97 324.8 0.1 3.8e-97 324.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EER22931.1 - 2.4e-60 203.9 0.0 6.6e-60 202.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER22931.1 - 8.9e-41 139.6 0.0 1.8e-40 138.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER22931.1 - 0.037 13.0 0.0 7.7 5.3 0.0 2.5 2 0 0 2 2 2 0 Kinase-like AA_permease_2 PF13520.1 EER22932.1 - 3.8e-97 325.5 39.7 4.9e-97 325.1 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER22932.1 - 7.8e-16 57.4 34.7 7.8e-16 57.4 24.1 2.0 1 1 0 1 1 1 1 Amino acid permease Pkinase PF00069.20 EER22933.1 - 4.4e-08 32.5 0.0 2e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Peptidase_M1 PF01433.15 EER22934.1 - 1.3e-141 472.2 1.1 1.7e-141 471.8 0.8 1.1 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EER22934.1 - 1.1e-92 310.7 0.7 2e-92 309.9 0.5 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EER22934.1 - 4.2e-20 72.1 0.3 7.6e-20 71.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Pkinase PF00069.20 EER22935.1 - 1.6e-05 24.2 0.0 1.6e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain His_Phos_2 PF00328.17 EER22936.1 - 6.2e-57 193.4 0.0 7.4e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3275 PF11679.3 EER22937.1 - 0.21 11.2 1.2 0.29 10.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Ribophorin_II PF05817.9 EER22938.1 - 1.7e-19 69.5 1.6 4.8e-19 68.0 1.1 1.6 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Piwi PF02171.12 EER22939.1 - 1.6e-74 250.6 0.0 2.2e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EER22939.1 - 3e-12 45.6 0.0 6.7e-12 44.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EER22939.1 - 5.8e-12 45.0 0.0 1.3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 PAZ domain adh_short PF00106.20 EER22940.1 - 5.6e-29 101.1 0.9 7.1e-29 100.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER22940.1 - 2.1e-27 96.4 0.0 2.5e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER22940.1 - 2.7e-17 63.0 0.2 3.9e-17 62.4 0.1 1.1 1 0 0 1 1 1 1 KR domain PLA2_B PF01735.13 EER22941.1 - 5.2e-189 628.4 0.0 6e-189 628.2 0.0 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PTCB-BRCT PF12738.2 EER22942.1 - 0.019 14.7 0.2 0.066 13.0 0.2 1.9 1 1 0 1 1 1 0 twin BRCT domain DAHP_synth_2 PF01474.11 EER22943.1 - 4.8e-198 657.9 0.0 5.5e-198 657.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family CPL PF08144.6 EER22944.1 - 0.077 12.8 0.4 0.11 12.2 0.2 1.4 1 1 0 1 1 1 0 CPL (NUC119) domain PsaN PF05479.6 EER22944.1 - 3.4 7.6 7.7 5 7.1 5.3 1.3 1 1 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) MFS_1 PF07690.11 EER22945.1 - 3.7e-22 78.5 22.4 3.7e-22 78.5 15.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Cut8_N PF14482.1 EER22945.1 - 1.3 9.0 7.5 3.9 7.5 0.5 3.0 3 0 0 3 3 3 0 Cut8 proteasome-binding domain Aldose_epim PF01263.15 EER22946.1 - 5.1e-45 153.8 0.0 6.4e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.3 EER22947.1 - 6.1e-133 443.3 0.1 1.1e-132 442.4 0.0 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Ric8 PF10165.4 EER22948.1 - 2.2e-112 376.1 0.0 2.5e-112 375.9 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Polysacc_synt_4 PF04669.8 EER22949.1 - 6.9e-25 87.5 1.3 3.9e-24 85.0 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Sugar_tr PF00083.19 EER22950.1 - 1.3e-140 468.9 22.1 1.6e-140 468.7 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER22950.1 - 4.9e-29 101.1 45.6 7.2e-24 84.1 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EER22950.1 - 1.1e-06 27.3 23.7 6.9e-05 21.4 3.2 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein Mannitol_dh_C PF08125.8 EER22951.1 - 1.7e-46 158.3 0.0 2.6e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EER22951.1 - 2.3e-18 66.5 0.2 7.2e-18 64.9 0.0 1.9 2 1 1 3 3 3 1 Mannitol dehydrogenase Rossmann domain SWIRM PF04433.12 EER22953.1 - 1.1e-17 63.9 0.1 3.5e-17 62.2 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 EER22953.1 - 1.6e-10 40.3 8.3 3e-10 39.4 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EER22953.1 - 2.3e-08 33.9 0.0 6.1e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PG_binding_1 PF01471.13 EER22953.1 - 0.016 15.2 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 Putative peptidoglycan binding domain MDH PF02315.11 EER22953.1 - 0.06 13.2 2.1 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Pkinase PF00069.20 EER22954.1 - 1.6e-70 237.2 0.0 2.2e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER22954.1 - 7.9e-33 113.6 0.0 1.1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EER22954.1 - 4.3e-10 39.9 0.3 1.1e-09 38.6 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EER22954.1 - 0.00038 19.5 0.0 0.00061 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Coatomer_WDAD PF04053.9 EER22955.1 - 1.2e-167 558.2 0.0 2.7e-167 557.0 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EER22955.1 - 5e-47 156.1 7.8 6.8e-11 41.6 0.2 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EER22955.1 - 0.00072 17.8 6.7 0.032 12.3 0.2 4.4 2 2 1 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EER22955.1 - 0.0049 16.6 0.0 4.4 7.1 0.0 3.5 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.9 EER22956.1 - 2.6e-22 78.1 0.1 2.6e-22 78.1 0.1 2.3 4 0 0 4 4 4 1 ETC complex I subunit conserved region YfcL PF08891.6 EER22956.1 - 1.8 8.6 4.4 1.8 8.6 0.2 2.2 2 0 0 2 2 2 0 YfcL protein Thioredoxin PF00085.15 EER22957.1 - 5e-44 148.2 0.0 2.9e-24 84.7 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EER22957.1 - 1.9e-13 50.6 0.0 0.0001 22.1 0.0 4.2 3 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EER22957.1 - 6.3e-07 29.4 1.0 0.0042 17.1 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EER22957.1 - 1.7e-06 28.1 0.9 0.23 11.6 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin-like domain HyaE PF07449.6 EER22957.1 - 0.00068 19.5 0.0 2 8.3 0.0 2.8 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 EER22957.1 - 0.015 15.3 3.9 0.048 13.6 0.1 3.4 4 0 0 4 4 4 0 Thioredoxin-like DUF3557 PF12078.3 EER22957.1 - 0.098 12.3 0.1 0.59 9.8 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3557) Fungal_trans_2 PF11951.3 EER22958.1 - 1.8e-92 309.8 0.4 2.8e-92 309.2 0.0 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER22958.1 - 1.5e-06 27.9 11.3 2.3e-06 27.4 7.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4250 PF14056.1 EER22958.1 - 0.16 11.7 0.1 0.45 10.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) SAM_2 PF07647.12 EER22959.1 - 1.4e-09 37.6 0.1 2.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EER22959.1 - 1.2e-07 31.7 0.1 2.7e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EER22959.1 - 3e-06 27.3 0.0 5.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 EER22959.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_9 PF15410.1 EER22959.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3628 PF12300.3 EER22959.1 - 0.12 12.4 4.1 0.3 11.1 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) SAM_PNT PF02198.11 EER22959.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain WD40 PF00400.27 EER22960.1 - 7.2e-29 98.6 20.1 1.1e-08 34.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EER22960.1 - 0.0089 14.2 0.0 0.013 13.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EER22960.1 - 0.082 12.6 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A HNH_2 PF13391.1 EER22961.1 - 1.4e-12 47.2 0.0 3.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease UAF_Rrn10 PF05234.6 EER22962.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 UAF complex subunit Rrn10 Mnd1 PF03962.10 EER22963.1 - 2.7e-49 167.3 1.8 3.2e-49 167.1 1.3 1.0 1 0 0 1 1 1 1 Mnd1 family Seryl_tRNA_N PF02403.17 EER22963.1 - 0.0034 17.3 4.4 0.0064 16.5 3.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain RNA_pol_Rpc34 PF05158.7 EER22963.1 - 0.015 14.4 0.2 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 RNA polymerase Rpc34 subunit Tektin PF03148.9 EER22963.1 - 0.015 13.8 0.6 0.031 12.8 0.2 1.6 1 1 0 1 1 1 0 Tektin family DUF342 PF03961.8 EER22963.1 - 0.019 13.4 0.7 0.022 13.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_TATA_bd PF12325.3 EER22963.1 - 0.025 14.2 2.9 0.059 13.1 2.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF4102 PF13356.1 EER22963.1 - 0.027 14.3 0.2 0.046 13.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4102) DsrD PF08679.6 EER22963.1 - 0.03 14.3 0.3 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) TBPIP PF07106.8 EER22963.1 - 0.06 12.8 1.6 0.08 12.4 1.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Psu PF07455.6 EER22963.1 - 0.074 12.5 1.0 0.44 10.0 0.3 2.0 1 1 1 2 2 2 0 Phage polarity suppression protein (Psu) DUF793 PF05633.6 EER22963.1 - 0.09 11.5 1.4 0.14 10.9 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) DASH_Duo1 PF08651.5 EER22963.1 - 0.092 12.3 0.3 0.53 9.8 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Duo1 WEMBL PF05701.6 EER22963.1 - 0.13 10.6 6.0 0.28 9.5 3.6 1.7 1 1 1 2 2 2 0 Weak chloroplast movement under blue light bZIP_1 PF00170.16 EER22963.1 - 7.1 6.6 6.5 17 5.4 0.3 3.2 4 0 0 4 4 3 0 bZIP transcription factor LacAB_rpiB PF02502.13 EER22964.1 - 6.5e-43 145.7 0.3 7.6e-43 145.5 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase TIM PF00121.13 EER22965.1 - 6.5e-48 162.9 0.0 1e-47 162.2 0.0 1.3 1 1 0 1 1 1 1 Triosephosphate isomerase U-box PF04564.10 EER22966.1 - 7.3e-24 83.5 0.0 1.5e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EER22966.1 - 1.5e-14 53.4 6.7 2.6e-13 49.4 1.7 2.5 1 1 1 2 2 2 1 TPR repeat TPR_2 PF07719.12 EER22966.1 - 5.1e-06 26.0 8.5 0.0033 17.2 0.9 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER22966.1 - 6e-06 26.7 3.8 0.0027 18.3 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EER22966.1 - 7.5e-05 22.1 4.9 0.001 18.5 1.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER22966.1 - 0.00012 22.3 5.8 0.0096 16.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EER22966.1 - 0.00059 19.7 1.6 0.31 11.0 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EER22966.1 - 0.0015 18.9 2.0 1.5 9.6 0.0 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat zf-Nse PF11789.3 EER22966.1 - 0.0063 16.0 0.0 0.018 14.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TPR_4 PF07721.9 EER22966.1 - 0.014 15.7 0.2 0.14 12.6 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EER22966.1 - 0.025 14.7 0.5 0.08 13.0 0.0 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CSS-motif PF12792.2 EER22966.1 - 0.054 12.8 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 CSS motif domain associated with EAL TPR_3 PF07720.7 EER22966.1 - 0.088 12.6 0.6 0.23 11.3 0.4 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EER22966.1 - 0.095 12.9 1.8 28 5.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EER22966.1 - 2.9 8.5 9.0 17 6.1 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ACBP PF00887.14 EER22967.1 - 5.5e-24 83.6 0.3 6.3e-24 83.4 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.7 EER22968.1 - 3.3e-145 484.0 0.0 4.4e-145 483.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EER22968.1 - 0.0019 17.9 0.1 0.089 12.5 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain DNA_gyraseB PF00204.20 EER22968.1 - 0.027 13.6 0.0 0.07 12.3 0.0 1.6 2 0 0 2 2 2 0 DNA gyrase B AA_permease_2 PF13520.1 EER22969.1 - 3.5e-65 220.1 44.5 4.3e-65 219.9 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER22969.1 - 2.3e-18 65.8 35.6 3.1e-18 65.3 24.7 1.2 1 0 0 1 1 1 1 Amino acid permease Caps_synth PF05704.7 EER22970.1 - 8.9e-10 38.1 0.0 2e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EER22970.1 - 0.0016 18.7 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Arrestin_N PF00339.24 EER22971.1 - 6.6e-14 51.9 0.0 3.9e-12 46.2 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EER22971.1 - 1.5e-05 25.1 0.0 0.0066 16.5 0.0 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain DHO_dh PF01180.16 EER22972.1 - 1.6e-59 201.3 0.1 4.4e-51 173.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EER22972.1 - 0.00077 18.7 0.1 0.72 9.0 0.0 2.6 2 0 0 2 2 2 2 PcrB family SelP_N PF04592.9 EER22973.1 - 1.3 8.3 8.6 1.8 7.9 6.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region zf-H2C2_2 PF13465.1 EER22974.1 - 1.2e-07 31.6 11.8 8e-06 25.8 1.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER22974.1 - 1.4e-06 28.2 13.9 0.00015 21.8 4.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EER22974.1 - 0.0017 18.5 16.8 0.015 15.6 4.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EER22974.1 - 0.0018 18.3 4.7 0.047 13.8 0.7 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EER22974.1 - 0.0025 17.9 7.5 0.0052 16.8 5.2 1.6 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.2 EER22974.1 - 0.13 12.0 1.4 0.23 11.3 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 EER22974.1 - 0.29 10.9 8.4 0.2 11.4 0.9 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2HC_2 PF13913.1 EER22974.1 - 4 7.2 8.4 7.2 6.3 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type APG5 PF04106.7 EER22975.1 - 2.4e-69 232.8 0.0 3e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 GMC_oxred_N PF00732.14 EER22976.1 - 2.2e-54 184.6 0.0 2.8e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EER22976.1 - 3e-35 121.6 0.0 5.2e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EER22976.1 - 0.0024 17.8 0.0 0.0057 16.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EER22976.1 - 0.013 14.3 0.0 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EER22976.1 - 0.015 14.2 0.1 0.024 13.5 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EER22976.1 - 0.058 12.2 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NmrA PF05368.8 EER22977.1 - 8.5e-28 97.1 0.0 2.5e-27 95.6 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EER22977.1 - 4e-07 30.2 0.0 5.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EER22977.1 - 0.00093 19.1 0.0 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain DUF2784 PF10861.3 EER22977.1 - 0.088 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Methyltransf_23 PF13489.1 EER22978.1 - 3.8e-22 78.7 0.1 7.8e-22 77.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER22978.1 - 2e-09 38.0 0.0 2.5e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER22978.1 - 4.8e-09 35.9 0.0 4.6e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER22978.1 - 1.8e-07 31.5 0.0 3.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER22978.1 - 1.5e-06 28.5 0.0 4.9e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER22978.1 - 0.00093 19.5 0.0 0.0033 17.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER22978.1 - 0.0039 17.2 0.0 0.015 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EER22978.1 - 0.016 14.2 0.0 0.044 12.8 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase PrmA PF06325.8 EER22978.1 - 0.033 13.3 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EER22978.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EER22978.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase SHR3_chaperone PF08229.6 EER22979.1 - 2.1e-81 271.6 0.0 2.5e-81 271.3 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 BpuJI_N PF11564.3 EER22979.1 - 0.11 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BpuJI - N terminal HlyIII PF03006.15 EER22979.1 - 2.4 7.5 6.7 0.25 10.7 1.7 1.4 2 0 0 2 2 2 0 Haemolysin-III related IncA PF04156.9 EER22980.1 - 0.39 10.3 1.3 0.57 9.7 0.1 1.7 2 0 0 2 2 2 0 IncA protein DUF2222 PF09984.4 EER22981.1 - 0.072 12.5 0.1 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) ABC_membrane PF00664.18 EER22983.1 - 4.6e-48 163.9 36.1 3.1e-27 95.6 12.0 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EER22983.1 - 3.9e-47 159.9 1.1 6.3e-28 97.7 0.0 3.1 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EER22983.1 - 2.6e-08 34.1 0.2 0.032 14.2 0.0 4.5 4 1 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EER22983.1 - 5.9e-06 26.3 0.5 0.11 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EER22983.1 - 2e-05 23.9 5.5 0.029 13.6 0.9 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EER22983.1 - 3.9e-05 23.5 0.1 0.035 14.0 0.0 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase Miro PF08477.8 EER22983.1 - 6.2e-05 23.4 2.2 0.36 11.3 0.1 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EER22983.1 - 7.8e-05 23.4 0.9 0.78 10.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EER22983.1 - 0.0003 20.2 4.2 0.14 11.6 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 EER22983.1 - 0.0013 17.9 0.6 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EER22983.1 - 0.0022 17.0 0.1 1.6 7.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.1 EER22983.1 - 0.0032 17.0 1.5 1.8 8.1 0.2 2.5 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EER22983.1 - 0.0043 15.8 2.2 1 8.0 0.2 2.4 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EER22983.1 - 0.0076 15.7 1.0 0.69 9.2 0.2 2.6 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EER22983.1 - 0.011 15.1 1.0 0.9 8.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EER22983.1 - 0.013 15.5 1.7 2.9 8.0 0.1 3.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EER22983.1 - 0.018 15.3 11.5 0.49 10.6 0.1 3.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 EER22983.1 - 0.034 13.8 0.7 3.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EER22983.1 - 0.034 13.9 6.8 0.54 10.0 0.1 3.6 3 0 0 3 3 3 0 Dynamin family AAA_28 PF13521.1 EER22983.1 - 0.036 14.0 2.4 0.23 11.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain ATP_bind_1 PF03029.12 EER22983.1 - 0.057 12.9 1.5 6.2 6.2 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EER22983.1 - 0.15 12.3 5.0 7.1 6.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain Prog_receptor PF02161.10 EER22983.1 - 0.2 10.4 1.0 0.36 9.6 0.7 1.3 1 0 0 1 1 1 0 Progesterone receptor AAA_19 PF13245.1 EER22983.1 - 0.2 11.4 1.6 0.61 9.8 0.3 2.4 2 0 0 2 2 2 0 Part of AAA domain CDC45 PF02724.9 EER22983.1 - 0.3 9.0 2.8 0.58 8.1 1.9 1.3 1 0 0 1 1 1 0 CDC45-like protein cobW PF02492.14 EER22983.1 - 1.4 8.3 3.4 3.3 7.1 0.4 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Aminotran_3 PF00202.16 EER22984.1 - 2.6e-104 348.7 0.0 3.2e-104 348.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EER22984.1 - 0.0022 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Glyco_transf_22 PF03901.12 EER22985.1 - 4.4e-79 266.4 15.3 5.4e-79 266.1 10.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ArfGap PF01412.13 EER22986.1 - 1.4e-40 137.6 0.0 2.9e-40 136.7 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf FtsJ PF01728.14 EER22987.1 - 1.9e-10 41.0 0.0 3.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EER22987.1 - 0.032 14.8 0.3 0.24 11.9 0.2 2.3 1 1 0 1 1 1 0 Methyltransferase domain DUF1726 PF08351.6 EER22987.1 - 0.044 13.4 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1726) HTH_19 PF12844.2 EER22987.1 - 0.11 12.5 0.0 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain SET PF00856.23 EER22988.1 - 2.8e-05 24.4 0.1 2.8e-05 24.4 0.1 4.0 4 1 0 4 4 4 2 SET domain PHD PF00628.24 EER22988.1 - 5.7e-05 22.7 10.0 0.00011 21.7 6.9 1.5 1 0 0 1 1 1 1 PHD-finger CDC73 PF05179.9 EER22989.1 - 2.2e-39 135.4 0.1 9.5e-38 130.1 0.1 2.6 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family RGS PF00615.14 EER22990.1 - 1.3e-30 105.9 0.0 2.8e-30 104.8 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EER22990.1 - 1.1e-22 79.5 0.0 3.4e-16 58.7 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF605 PF04652.11 EER22990.1 - 1.9 7.8 9.1 3.2 7.0 6.3 1.3 1 0 0 1 1 1 0 Vta1 like ORC4_C PF14629.1 EER22991.1 - 5e-54 182.7 0.0 7.6e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EER22991.1 - 1.3e-13 51.3 0.1 5.2e-13 49.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EER22991.1 - 6.8e-07 29.4 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EER22991.1 - 2.1e-06 27.9 0.0 5.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EER22991.1 - 0.0028 17.3 0.0 0.0071 16.0 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EER22991.1 - 0.004 16.6 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EER22991.1 - 0.0042 16.7 0.0 0.013 15.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EER22991.1 - 0.0062 16.2 0.4 0.048 13.3 0.3 2.3 1 1 0 1 1 1 1 NACHT domain DUF815 PF05673.8 EER22991.1 - 0.0083 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EER22991.1 - 0.0091 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.1 EER22991.1 - 0.028 14.2 0.1 0.15 11.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EER22991.1 - 0.038 13.4 0.0 0.091 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EER22991.1 - 0.066 12.1 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EER22991.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EER22991.1 - 0.27 10.7 2.0 1.2 8.6 0.2 2.7 2 1 0 2 2 2 0 AAA domain 4HBT PF03061.17 EER22992.1 - 1e-11 44.7 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily NOT2_3_5 PF04153.13 EER22993.1 - 1.3e-32 112.4 0.0 1.3e-32 112.4 0.0 2.3 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 EER22994.1 - 2.5e-20 72.1 0.0 3.7e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GDI PF00996.13 EER22995.1 - 1e-179 597.4 0.0 1.4e-179 597.0 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EER22995.1 - 0.051 13.6 0.1 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SMC_N PF02463.14 EER22996.1 - 1.4e-67 227.1 11.8 1.2e-66 224.1 8.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EER22996.1 - 5.7e-23 81.1 0.9 6.7e-22 77.7 0.2 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EER22996.1 - 2.2e-16 60.8 3.7 2.2e-16 60.8 2.6 6.3 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EER22996.1 - 4.7e-12 46.4 10.5 9e-06 25.8 0.2 3.7 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EER22996.1 - 8.2e-05 22.0 0.0 0.00019 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 EER22996.1 - 0.0032 16.7 8.0 0.0032 16.7 5.5 7.5 2 2 5 7 7 7 2 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EER22996.1 - 0.0064 15.7 31.0 0.49 9.5 0.8 5.9 4 2 3 7 7 7 4 Reovirus sigma C capsid protein ABC_tran PF00005.22 EER22996.1 - 0.059 13.6 0.0 0.059 13.6 0.0 5.5 4 2 0 4 4 4 0 ABC transporter CUE PF02845.11 EER22997.1 - 8.4e-11 41.1 0.0 1.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain HTH_32 PF13565.1 EER22997.1 - 0.08 13.7 0.4 0.2 12.4 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Sld5 PF05916.6 EER22998.1 - 8.4e-31 106.4 0.0 1.2e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein TPR_11 PF13414.1 EER22999.1 - 1.4e-10 40.6 1.3 8.4e-07 28.5 0.0 2.9 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EER22999.1 - 7.9e-09 35.9 3.9 0.00081 19.9 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EER22999.1 - 1.5e-06 27.9 3.6 1.4e-05 24.8 0.2 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER22999.1 - 4.1e-06 26.1 0.1 0.44 10.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EER22999.1 - 7.8e-05 22.3 3.4 0.27 11.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER22999.1 - 0.0025 17.8 0.3 0.12 12.5 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EER22999.1 - 0.0077 15.9 0.1 6.3 6.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER22999.1 - 0.011 15.5 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EER22999.1 - 0.012 16.1 8.3 0.78 10.5 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.3 EER22999.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_19 PF14559.1 EER22999.1 - 0.1 12.9 3.7 0.89 9.9 0.1 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat DIE2_ALG10 PF04922.7 EER23000.1 - 4e-77 259.7 19.4 3.9e-76 256.5 13.4 2.3 1 1 0 1 1 1 1 DIE2/ALG10 family Polyketide_cyc PF03364.15 EER23001.1 - 2.6e-18 66.2 0.0 3.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Sod_Fe_C PF02777.13 EER23002.1 - 1.6e-15 56.8 0.0 2.1e-06 27.5 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain PIG-S PF10510.4 EER23004.1 - 2e-170 567.9 1.9 2.3e-170 567.6 1.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein FimP PF09766.4 EER23005.1 - 9.3e-26 90.7 8.4 1.3e-25 90.2 5.8 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EER23005.1 - 0.0069 16.3 10.9 0.28 11.1 0.3 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) K-box PF01486.12 EER23005.1 - 0.04 13.7 0.2 0.04 13.7 0.2 2.5 2 0 0 2 2 2 0 K-box region DUF972 PF06156.8 EER23005.1 - 0.89 9.9 5.3 8 6.8 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF349 PF03993.7 EER23005.1 - 2.9 8.1 9.5 0.26 11.4 3.2 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) HlyIII PF03006.15 EER23006.1 - 3.8e-57 193.2 22.1 5.1e-57 192.8 15.3 1.2 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 EER23006.1 - 0.0081 15.9 0.8 0.0081 15.9 0.6 2.0 2 0 0 2 2 2 1 Microsomal signal peptidase 12 kDa subunit (SPC12) YfhO PF09586.5 EER23006.1 - 5.3 4.9 12.8 7.4 4.4 8.9 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Methyltransf_12 PF08242.7 EER23007.1 - 9.4e-17 61.3 0.0 2.8e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23007.1 - 3.9e-13 49.7 0.0 9.5e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER23007.1 - 9.3e-12 44.9 0.2 3.6e-11 43.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER23007.1 - 2.1e-10 40.8 0.0 4.2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER23007.1 - 5.4e-10 39.8 0.0 1.2e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER23007.1 - 5.1e-09 35.8 0.0 9.4e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER23007.1 - 1.5e-07 30.8 0.0 2.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EER23007.1 - 3.3e-06 27.1 0.0 6.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER23007.1 - 0.00012 21.4 0.0 0.00025 20.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain DUF3419 PF11899.3 EER23007.1 - 0.00089 18.0 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) NNMT_PNMT_TEMT PF01234.12 EER23007.1 - 0.0012 17.8 0.0 0.083 11.8 0.0 2.2 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_24 PF13578.1 EER23007.1 - 0.0018 19.0 0.0 0.0058 17.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EER23007.1 - 0.002 17.8 0.0 0.028 14.0 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.4 EER23007.1 - 0.0065 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EER23007.1 - 0.0067 15.5 0.0 0.014 14.4 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EER23007.1 - 0.018 14.2 0.0 0.033 13.3 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 EER23007.1 - 0.041 13.0 0.0 0.063 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Diphthamide_syn PF01866.12 EER23009.1 - 1.4e-49 169.0 0.0 4.2e-49 167.4 0.0 1.8 2 1 0 2 2 2 1 Putative diphthamide synthesis protein NUDIX_4 PF14815.1 EER23009.1 - 0.021 14.2 0.0 0.047 13.1 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Fe-ADH PF00465.14 EER23010.1 - 2.3e-73 246.9 0.1 2.6e-73 246.7 0.1 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EER23010.1 - 9.4e-15 54.5 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase PQQ_2 PF13360.1 EER23011.1 - 5e-05 22.8 3.4 0.00084 18.8 0.1 2.3 1 1 0 2 2 2 1 PQQ-like domain WD40 PF00400.27 EER23011.1 - 0.0061 16.4 5.6 0.28 11.1 0.2 4.3 4 1 0 4 4 4 1 WD domain, G-beta repeat Nup160 PF11715.3 EER23011.1 - 0.15 10.1 0.1 0.26 9.3 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nop14 PF04147.7 EER23011.1 - 0.39 8.5 4.8 0.45 8.3 3.3 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EER23011.1 - 6 4.7 9.3 8.3 4.3 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Hairy_orange PF07527.8 EER23012.1 - 0.059 13.1 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 0 Hairy Orange DUF3638 PF12340.3 EER23013.1 - 6.3e-80 267.4 0.4 2.4e-69 232.8 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EER23013.1 - 3.7e-15 54.7 0.0 8.6e-15 53.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) SOR_SNZ PF01680.12 EER23013.1 - 0.99 8.9 0.0 2.3 7.7 0.0 1.5 1 0 0 1 1 1 0 SOR/SNZ family JmjC PF02373.17 EER23014.1 - 1.6e-06 28.3 0.0 3.6e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase ZZ PF00569.12 EER23014.1 - 6.3e-06 25.6 7.5 6.3e-06 25.6 5.2 2.5 2 0 0 2 2 2 1 Zinc finger, ZZ type zf-4CXXC_R1 PF10497.4 EER23014.1 - 0.00043 20.3 9.8 0.00043 20.3 6.8 2.2 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EER23014.1 - 0.0076 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cu-oxidase_3 PF07732.10 EER23015.1 - 4.5e-42 142.5 0.7 7.6e-41 138.5 0.2 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EER23015.1 - 6.2e-36 122.9 1.3 1.5e-32 111.9 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EER23015.1 - 4.8e-26 91.5 0.0 1.1e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Sulfatase PF00884.18 EER23016.1 - 1.8e-19 70.0 0.2 3.9e-19 68.9 0.1 1.5 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EER23016.1 - 8.2e-07 28.6 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EER23016.1 - 0.024 13.0 0.1 0.037 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EER23016.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily AMP-binding PF00501.23 EER23017.1 - 1.7e-68 230.9 0.0 2.3e-68 230.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER23017.1 - 4.8e-10 40.2 0.0 8.4e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aminotran_1_2 PF00155.16 EER23018.1 - 4.5e-44 150.8 0.0 5.7e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EER23018.1 - 7.6e-11 41.6 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EER23018.1 - 8.8e-09 34.1 0.0 1.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EER23018.1 - 3.4e-07 29.6 0.0 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EER23018.1 - 5.5e-07 28.6 0.0 8.4e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V ABC2_membrane PF01061.19 EER23019.1 - 1e-37 129.3 19.7 5.9e-37 126.8 13.9 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EER23019.1 - 3.1e-25 89.0 0.0 6.7e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EER23019.1 - 1.9e-09 37.9 0.1 4.1e-08 33.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EER23019.1 - 4.1e-07 29.3 24.0 4.1e-07 29.3 16.7 2.0 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EER23019.1 - 6.5e-05 22.4 0.1 0.012 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EER23019.1 - 0.0019 17.6 0.1 0.004 16.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EER23019.1 - 0.0051 15.9 0.0 0.85 8.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EER23019.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EER23019.1 - 0.019 15.0 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Retinal PF15449.1 EER23019.1 - 0.043 11.4 9.1 0.057 11.0 6.3 1.0 1 0 0 1 1 1 0 Retinal protein NACHT PF05729.7 EER23019.1 - 0.047 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain SMC_N PF02463.14 EER23019.1 - 0.05 12.8 0.0 0.53 9.4 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EER23019.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EER23019.1 - 0.082 13.7 0.0 0.2 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EER23019.1 - 0.082 13.2 0.2 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EER23019.1 - 0.093 12.6 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EER23019.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EER23019.1 - 0.1 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glycophorin_A PF01102.13 EER23019.1 - 0.11 12.2 3.2 0.23 11.2 0.0 2.8 3 0 0 3 3 3 0 Glycophorin A AAA_18 PF13238.1 EER23019.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EER23019.1 - 0.24 11.0 0.0 0.41 10.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase hEGF PF12661.2 EER23019.1 - 0.56 10.3 24.8 0.13 12.3 1.4 3.9 4 0 0 4 4 3 0 Human growth factor-like EGF EGF_2 PF07974.8 EER23019.1 - 3.3 7.9 36.9 0.039 14.1 8.3 4.0 4 0 0 4 4 4 0 EGF-like domain MFS_1 PF07690.11 EER23020.1 - 1.6e-21 76.4 50.4 5.1e-20 71.4 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EER23020.1 - 3.2e-06 25.8 15.2 0.00022 19.8 10.5 2.4 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Cornichon PF03311.9 EER23021.1 - 1.9e-53 179.9 12.6 2.2e-53 179.8 8.7 1.0 1 0 0 1 1 1 1 Cornichon protein Peptidase_M50 PF02163.17 EER23021.1 - 1.6 7.6 5.2 2.1 7.2 3.6 1.2 1 0 0 1 1 1 0 Peptidase family M50 HeLo PF14479.1 EER23022.1 - 1.6e-12 47.6 0.7 3.7e-12 46.4 0.5 1.6 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 EER23022.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.12 EER23022.1 - 0.061 12.3 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Ank_2 PF12796.2 EER23023.1 - 1.5e-42 143.8 0.3 1e-11 45.0 0.0 6.6 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EER23023.1 - 9.1e-31 104.1 0.6 5.5e-05 22.7 0.0 10.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 EER23023.1 - 1.4e-27 95.5 0.4 3.1e-06 27.5 0.0 7.1 6 1 2 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER23023.1 - 7.2e-24 83.2 2.1 0.0041 17.3 0.0 8.2 6 3 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER23023.1 - 4.2e-23 79.1 2.0 0.012 15.7 0.0 9.6 9 1 0 9 9 9 4 Ankyrin repeat Pkinase PF00069.20 EER23023.1 - 1.6e-21 76.6 0.0 2.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23023.1 - 6.4e-09 35.2 0.0 1.7e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EER23023.1 - 0.01 14.6 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EER23023.1 - 0.025 13.5 0.0 0.056 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like DUF4495 PF14906.1 EER23025.1 - 0.058 12.3 0.0 0.076 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) MecA PF05389.7 EER23025.1 - 0.066 12.7 0.2 0.11 12.0 0.1 1.3 1 1 0 1 1 1 0 Negative regulator of genetic competence (MecA) WD40 PF00400.27 EER23027.1 - 8.9e-38 126.8 15.0 3.3e-10 39.4 0.7 7.1 7 1 0 7 7 7 5 WD domain, G-beta repeat Oxidored_molyb PF00174.14 EER23028.1 - 7.1e-45 152.4 0.0 1.3e-44 151.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EER23028.1 - 2.9e-39 133.6 0.4 5.7e-39 132.7 0.2 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 EER23028.1 - 1.7e-21 76.1 0.0 5.5e-21 74.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EER23028.1 - 3.4e-21 75.8 0.0 1.8e-20 73.4 0.0 2.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EER23028.1 - 3e-19 68.5 0.1 1.1e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EER23028.1 - 0.00082 19.3 0.9 0.0024 17.7 0.0 2.3 3 0 0 3 3 3 1 Ferric reductase NAD binding domain KBP_C PF12309.3 EER23028.1 - 0.43 9.4 5.5 0.72 8.7 3.8 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal EF-hand_1 PF00036.27 EER23029.1 - 7.7e-11 40.4 10.2 3.5e-05 22.7 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 EER23029.1 - 1.3e-10 41.2 2.6 8.5e-10 38.6 1.2 2.8 2 0 0 2 2 2 1 EF-hand domain pair ZZ PF00569.12 EER23029.1 - 1.8e-10 40.2 5.0 3.1e-10 39.4 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_6 PF13405.1 EER23029.1 - 7.6e-10 37.8 5.6 0.00026 20.6 0.1 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EER23029.1 - 6.2e-05 22.5 6.7 0.016 14.8 0.2 3.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EER23029.1 - 0.058 12.7 12.2 0.12 11.8 0.1 3.6 5 0 0 5 5 5 0 EF hand C1_3 PF07649.7 EER23029.1 - 0.76 9.8 7.5 1.4 8.9 5.2 1.5 1 0 0 1 1 1 0 C1-like domain MFS_1 PF07690.11 EER23030.1 - 3.6e-49 167.3 48.1 3.6e-49 167.3 33.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER23030.1 - 1e-11 44.0 9.0 1e-11 44.0 6.3 3.1 1 1 2 3 3 3 2 Sugar (and other) transporter Cation_efflux PF01545.16 EER23030.1 - 0.051 12.6 7.9 0.13 11.3 5.4 1.8 1 0 0 1 1 1 0 Cation efflux family MtrB PF05440.7 EER23030.1 - 0.84 9.7 0.0 0.84 9.7 0.0 2.7 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Transgly_assoc PF04226.8 EER23030.1 - 7.9 6.6 21.0 0.17 11.9 2.1 4.4 4 0 0 4 4 4 0 Transglycosylase associated protein Peptidase_M24 PF00557.19 EER23031.1 - 1.2e-43 149.1 0.0 1.3e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 FAD_binding_3 PF01494.14 EER23032.1 - 5.3e-14 52.0 0.0 1.5e-12 47.2 0.0 2.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EER23032.1 - 5.3e-05 22.4 2.0 0.0035 16.5 0.2 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 EER23032.1 - 0.00044 19.2 0.0 0.0011 17.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EER23032.1 - 0.00069 19.9 0.0 0.0055 17.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EER23032.1 - 0.00075 18.4 0.0 0.0019 17.0 0.0 1.7 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EER23032.1 - 0.0014 18.6 0.7 0.0061 16.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER23032.1 - 0.0015 18.4 0.0 0.0071 16.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EER23032.1 - 0.0028 16.2 0.1 0.0045 15.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EER23032.1 - 0.0043 15.9 0.1 0.0074 15.1 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EER23032.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Baculo_ME53 PF06061.6 EER23033.1 - 0.07 12.1 0.1 0.097 11.6 0.1 1.1 1 0 0 1 1 1 0 Baculoviridae ME53 Ribosomal_S8 PF00410.14 EER23034.1 - 3.8e-24 84.9 0.0 6.8e-24 84.1 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.15 EER23037.1 - 3.5e-98 328.7 0.0 5.3e-98 328.1 0.0 1.2 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ICMT PF04140.9 EER23037.1 - 0.16 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1769 PF08588.5 EER23038.1 - 2.7e-28 97.6 0.1 5.7e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) APH PF01636.18 EER23039.1 - 5.6e-07 29.5 0.3 9.9e-05 22.1 0.2 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family NAD_binding_8 PF13450.1 EER23040.1 - 3.2e-10 39.8 0.0 7.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EER23040.1 - 3e-09 36.4 0.2 1.5e-07 30.8 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EER23040.1 - 7.8e-09 34.8 0.0 8.1e-05 21.6 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EER23040.1 - 8.6e-07 28.1 0.2 1.2e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EER23040.1 - 9e-07 29.1 0.0 0.01 15.9 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EER23040.1 - 1.8e-06 26.7 0.1 3e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EER23040.1 - 4e-05 23.5 0.1 0.00026 20.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EER23040.1 - 6.3e-05 22.1 0.1 0.00029 20.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EER23040.1 - 0.00042 20.6 0.5 0.0075 16.6 0.1 2.5 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER23040.1 - 0.00058 19.0 0.1 0.0011 18.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EER23040.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.19 EER23040.1 - 0.017 14.2 0.0 0.048 12.7 0.0 1.7 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase TrkA_N PF02254.13 EER23040.1 - 0.018 15.0 0.2 0.032 14.2 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain IlvN PF07991.7 EER23040.1 - 0.039 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EER23040.1 - 0.05 13.3 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.1 EER23040.1 - 0.052 13.8 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EER23040.1 - 0.055 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EER23040.1 - 0.058 13.1 0.1 0.8 9.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EER23040.1 - 0.073 11.9 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EER23040.1 - 0.1 11.1 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MAD PF05557.8 EER23041.1 - 0.0011 17.2 29.5 0.0011 17.2 20.5 2.9 2 1 1 3 3 3 2 Mitotic checkpoint protein Tropomyosin_1 PF12718.2 EER23041.1 - 0.0055 16.5 9.2 0.0055 16.5 6.4 5.7 4 1 3 7 7 7 2 Tropomyosin like TMF_TATA_bd PF12325.3 EER23041.1 - 0.0079 15.9 6.8 0.0079 15.9 4.7 6.2 4 1 2 6 6 6 1 TATA element modulatory factor 1 TATA binding SlyX PF04102.7 EER23041.1 - 0.014 15.7 5.1 0.014 15.7 3.5 5.5 4 1 1 5 5 4 0 SlyX ADIP PF11559.3 EER23041.1 - 0.042 13.7 49.9 0.17 11.8 0.1 6.6 2 1 4 6 6 6 0 Afadin- and alpha -actinin-Binding DUF869 PF05911.6 EER23041.1 - 0.13 10.5 37.2 0.052 11.7 20.6 2.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) DASH_Hsk3 PF08227.6 EER23041.1 - 0.26 11.5 6.6 0.58 10.4 0.3 3.4 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like DUF2730 PF10805.3 EER23041.1 - 0.27 10.9 12.1 1.1 8.9 0.4 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) Tropomyosin PF00261.15 EER23041.1 - 0.28 10.2 60.6 0.013 14.5 3.4 6.1 3 1 3 6 6 6 0 Tropomyosin Filament PF00038.16 EER23041.1 - 0.9 8.9 50.1 0.52 9.7 7.5 5.1 3 1 1 5 5 5 0 Intermediate filament protein FH2 PF02181.18 EER23041.1 - 1.3 7.8 25.2 0.052 12.4 6.2 3.3 1 1 1 3 3 3 0 Formin Homology 2 Domain Reo_sigmaC PF04582.7 EER23041.1 - 1.3 8.0 13.7 0.68 9.0 2.8 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein KxDL PF10241.4 EER23041.1 - 3.1 7.7 16.8 0.046 13.6 2.8 4.0 2 1 2 4 4 4 0 Uncharacterized conserved protein DUF2360 PF10152.4 EER23041.1 - 9.1 6.5 16.2 8.7 6.6 3.9 3.9 3 1 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) PK PF00224.16 EER23042.1 - 7.1e-170 564.2 3.2 8.7e-170 563.9 2.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EER23042.1 - 8.7e-32 109.1 0.0 5.5e-31 106.5 0.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EER23042.1 - 0.00017 20.5 0.9 0.00053 18.9 0.5 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EER23042.1 - 0.0046 15.8 0.1 0.08 11.8 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DUF1748 PF08520.5 EER23043.1 - 4.2e-36 122.4 0.0 4.7e-36 122.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) DUF3506 PF12014.3 EER23044.1 - 5.2e-43 146.1 0.0 1.9e-42 144.2 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EER23044.1 - 5.8e-09 35.5 1.4 1.3e-08 34.3 1.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER23044.1 - 2.1e-06 27.2 0.2 3.9e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EER23044.1 - 0.0073 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like domain PIP5K PF01504.13 EER23045.1 - 2.8e-61 206.8 0.2 5.6e-61 205.8 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EER23045.1 - 1.5e-26 93.1 0.0 2.2e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EER23045.1 - 1.2e-13 50.7 9.2 1.2e-13 50.7 6.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger Glyco_transf_5 PF08323.6 EER23045.1 - 0.26 10.7 0.0 0.68 9.3 0.0 1.7 1 0 0 1 1 1 0 Starch synthase catalytic domain TPP1 PF10341.4 EER23046.1 - 1.2e-16 60.6 0.0 2.5e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD SUR7 PF06687.7 EER23047.1 - 3.4e-45 154.2 0.8 4.1e-45 153.9 0.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family PMP22_Claudin PF00822.15 EER23047.1 - 0.07 12.7 9.6 0.43 10.2 4.3 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family WD40 PF00400.27 EER23048.1 - 6.7e-19 67.0 21.0 6e-08 32.2 0.2 9.1 10 1 0 10 10 10 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EER23048.1 - 0.03 13.0 1.3 3.1 6.4 0.0 3.8 2 2 1 4 4 4 0 Nup133 N terminal like XPG_N PF00752.12 EER23049.1 - 4e-35 120.0 0.0 9.6e-35 118.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EER23049.1 - 6e-25 87.1 0.0 1.5e-24 85.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EER23049.1 - 0.0013 18.9 0.0 0.005 17.0 0.0 2.1 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Transposase_20 PF02371.11 EER23049.1 - 0.014 15.4 0.0 0.053 13.6 0.0 2.0 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family UIM PF02809.15 EER23049.1 - 0.18 11.4 3.0 0.2 11.3 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif Pil1 PF13805.1 EER23050.1 - 2.2e-153 509.1 0.2 2.7e-153 508.8 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EER23050.1 - 0.021 14.1 2.1 0.03 13.6 0.6 1.7 1 1 1 2 2 2 0 FAM92 protein Spc7_N PF15402.1 EER23051.1 - 0 1143.2 52.6 0 1142.7 36.5 1.2 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EER23051.1 - 7.1e-115 383.1 8.9 1.5e-114 382.0 6.2 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Ribosomal_S17 PF00366.15 EER23052.1 - 6.7e-31 106.1 1.3 1e-30 105.5 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 MAGUK_N_PEST PF10608.4 EER23053.1 - 0.01 16.2 1.6 1.2 9.6 0.4 3.4 3 1 0 3 3 3 0 Polyubiquitination (PEST) N-terminal domain of MAGUK TolB_N PF04052.8 EER23053.1 - 0.019 15.0 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 TolB amino-terminal domain LSM PF01423.17 EER23054.1 - 5.1e-06 25.9 0.0 6.5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain Metallophos PF00149.23 EER23055.1 - 7.9e-42 142.9 0.2 1e-41 142.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EER23056.1 - 9e-32 107.7 6.2 3.2e-07 29.9 0.0 7.4 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EER23056.1 - 5.9e-05 22.8 0.4 0.026 14.2 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EER23056.1 - 0.00081 18.8 3.6 0.00081 18.8 0.1 2.8 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.7 EER23056.1 - 0.035 13.7 1.6 6.4 6.5 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cmc1 PF08583.5 EER23057.1 - 0.0011 18.6 2.7 0.0024 17.5 1.9 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2352 PF09817.4 EER23057.1 - 0.12 10.5 0.1 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2352) Sugar_tr PF00083.19 EER23059.1 - 1.2e-93 314.2 27.7 1.4e-93 313.9 19.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER23059.1 - 1.6e-16 59.9 33.2 4.3e-16 58.5 23.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Grp1_Fun34_YaaH PF01184.14 EER23060.1 - 9.5e-80 266.8 20.4 1.2e-79 266.5 14.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DIM PF08194.7 EER23060.1 - 0.36 10.7 3.7 0.25 11.3 0.2 2.4 2 0 0 2 2 2 0 DIM protein ANTH PF07651.11 EER23061.1 - 9.4e-56 188.5 0.8 9.9e-56 188.4 0.0 1.4 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 EER23061.1 - 9.7e-10 38.3 0.0 8.3e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 ENTH domain Med3 PF11593.3 EER23062.1 - 0.00042 19.6 4.8 0.0005 19.4 3.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Memo PF01875.12 EER23063.1 - 1.1e-62 211.4 0.0 2.1e-62 210.4 0.0 1.4 1 1 0 1 1 1 1 Memo-like protein TroA PF01297.12 EER23063.1 - 0.17 11.0 0.0 0.38 9.9 0.0 1.5 2 0 0 2 2 2 0 Periplasmic solute binding protein family Rad4 PF03835.10 EER23064.1 - 1.4e-16 60.1 6.1 2.5e-16 59.3 4.2 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EER23064.1 - 3.2e-11 43.4 1.4 6.9e-11 42.3 1.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.27 EER23065.1 - 2.3e-11 43.1 11.6 0.54 10.2 0.1 8.7 10 1 0 10 10 10 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EER23065.1 - 4.8e-05 22.9 0.8 0.00095 18.6 0.1 2.8 3 0 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 EER23065.1 - 0.011 15.3 0.0 0.95 9.1 0.0 3.2 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 EER23065.1 - 0.019 13.7 0.0 0.033 12.9 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region IL1 PF00340.14 EER23065.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Interleukin-1 / 18 Cyclin_N PF00134.18 EER23066.1 - 1.4e-35 121.6 0.1 2.8e-35 120.6 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EER23066.1 - 2.2e-09 37.2 0.3 6.9e-09 35.6 0.2 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Acyl_transf_3 PF01757.17 EER23067.1 - 4.8e-19 68.3 31.9 1.2e-18 67.0 22.1 1.7 1 1 0 1 1 1 1 Acyltransferase family Methyltransf_23 PF13489.1 EER23068.1 - 5.5e-19 68.4 0.0 8.4e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23068.1 - 8.6e-10 38.9 0.0 1.6e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER23068.1 - 3.2e-09 37.3 0.0 4e-08 33.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER23068.1 - 2.9e-08 33.4 0.0 3e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER23068.1 - 3.5e-07 30.6 0.0 2.9e-06 27.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER23068.1 - 1.5e-05 25.2 0.0 5.2e-05 23.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER23068.1 - 0.0021 18.0 0.0 0.0084 16.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EER23068.1 - 0.0095 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EER23068.1 - 0.02 14.0 0.0 0.2 10.7 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EER23068.1 - 0.024 13.7 0.0 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EER23068.1 - 0.027 13.5 0.0 0.06 12.4 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EER23068.1 - 0.029 13.4 0.0 0.07 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EER23068.1 - 0.044 13.1 0.0 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain DUF938 PF06080.7 EER23068.1 - 0.071 12.6 0.0 0.15 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EER23068.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Amidohydro_2 PF04909.9 EER23069.1 - 9e-11 41.8 0.3 2.8e-10 40.2 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EER23069.1 - 0.0012 18.8 0.1 0.0018 18.3 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EER23069.1 - 0.0014 18.3 0.3 0.061 12.9 0.2 2.1 1 1 0 1 1 1 1 Amidohydrolase family FKBP_C PF00254.23 EER23070.1 - 3.3e-31 107.1 0.0 4e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.23 EER23071.1 - 2.2e-14 53.0 0.0 3.1e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain T5orf172 PF10544.4 EER23072.1 - 1e-19 70.7 2.0 2.5e-19 69.5 1.4 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EER23072.1 - 7.8e-19 67.9 3.5 2e-18 66.6 2.4 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Zip PF02535.17 EER23074.1 - 5.3e-60 203.0 4.6 6e-60 202.8 3.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Innate_immun PF12782.2 EER23074.1 - 3.9 6.6 7.8 5.6 6.0 5.4 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Tom37_C PF11801.3 EER23075.1 - 5.7e-42 143.4 0.0 8.8e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EER23075.1 - 1.8e-25 88.9 0.3 1.2e-23 83.1 0.0 2.7 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein NAPRTase PF04095.11 EER23077.1 - 2.7e-49 167.6 0.0 1.7e-25 89.7 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF4303 PF14136.1 EER23077.1 - 0.037 13.6 0.1 0.069 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) p450 PF00067.17 EER23078.1 - 2.1e-48 165.0 0.0 3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SNARE PF05739.14 EER23079.1 - 6.2e-10 38.6 2.5 6.2e-10 38.6 1.7 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EER23079.1 - 2.2e-05 24.5 9.8 0.0006 19.9 4.9 2.8 1 1 1 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 EER23079.1 - 0.0006 19.7 5.6 0.0033 17.4 0.2 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Spectrin PF00435.16 EER23079.1 - 0.0021 18.3 5.6 1.2 9.4 0.0 3.4 2 1 2 4 4 4 2 Spectrin repeat Rifin_STEVOR PF02009.11 EER23079.1 - 0.011 15.4 6.7 0.022 14.3 4.6 1.5 1 1 0 1 1 1 0 Rifin/stevor family PTA_PTB PF01515.14 EER23079.1 - 0.019 14.0 3.3 0.027 13.5 2.3 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase DUF4370 PF14290.1 EER23079.1 - 0.024 14.0 1.0 0.038 13.4 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) HHH_2 PF12826.2 EER23079.1 - 0.03 14.1 1.4 0.074 12.9 0.3 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif MCPsignal PF00015.16 EER23079.1 - 0.061 12.8 13.4 0.02 14.4 5.6 2.3 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Phospholamban PF04272.9 EER23079.1 - 0.088 12.2 2.2 0.4 10.1 1.5 2.2 1 0 0 1 1 1 0 Phospholamban Baculo_PEP_C PF04513.7 EER23079.1 - 0.12 12.1 2.8 12 5.7 0.1 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EER23079.1 - 0.18 11.6 0.1 0.18 11.6 0.0 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 PBP1_TM PF14812.1 EER23079.1 - 0.2 11.9 0.1 0.2 11.9 0.0 2.4 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF805 PF05656.9 EER23079.1 - 0.23 11.3 0.8 0.45 10.3 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) BLOC1_2 PF10046.4 EER23079.1 - 0.26 11.4 6.9 2.4 8.3 0.3 3.5 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Vps51 PF08700.6 EER23079.1 - 0.34 10.7 6.2 3.5 7.5 1.3 3.3 2 1 0 2 2 2 0 Vps51/Vps67 DUF3753 PF12575.3 EER23079.1 - 0.36 10.6 2.9 0.75 9.6 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) T2SF PF00482.18 EER23079.1 - 0.5 10.2 6.1 14 5.6 0.1 3.2 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F LMBR1 PF04791.11 EER23079.1 - 0.53 8.7 3.9 0.84 8.1 2.7 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Tweety PF04906.8 EER23079.1 - 0.8 8.0 6.5 0.24 9.7 2.4 1.7 1 1 1 2 2 2 0 Tweety NPV_P10 PF05531.7 EER23079.1 - 4.3 7.6 6.6 8.1 6.7 0.8 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EER23079.1 - 6.5 6.5 8.3 7.7 6.3 1.6 3.2 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) BolA PF01722.13 EER23080.1 - 8.6e-30 102.5 0.6 8.6e-30 102.5 0.4 1.4 2 0 0 2 2 2 1 BolA-like protein AMP-binding PF00501.23 EER23081.1 - 2.8e-64 217.0 0.0 3.2e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER23081.1 - 6.2e-13 49.4 0.0 1.4e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IF4E PF01652.13 EER23082.1 - 1.1e-60 203.9 0.4 1.4e-60 203.6 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 EER23083.1 - 1e-25 89.1 1.0 1.6e-25 88.5 0.7 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 EER23084.1 - 1.1e-28 98.6 2.7 2.4e-28 97.6 1.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EER23084.1 - 1.5e-22 78.6 0.0 2.7e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PIN_4 PF13638.1 EER23086.1 - 0.029 14.4 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 PIN domain MAGE_N PF12440.3 EER23086.1 - 3.1 8.1 8.8 0.72 10.1 3.1 2.1 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Rhodanese PF00581.15 EER23087.1 - 2e-22 79.6 0.0 1.9e-11 44.2 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain zf-Apc11 PF12861.2 EER23088.1 - 1.1e-45 153.4 8.9 1.2e-45 153.2 6.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EER23088.1 - 1.8e-32 111.2 9.2 2e-32 111.0 6.4 1.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EER23088.1 - 9.6e-09 34.9 16.9 4.9e-08 32.6 11.5 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EER23088.1 - 6.5e-05 22.8 12.3 0.00045 20.1 8.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER23088.1 - 0.00015 21.3 12.5 0.00021 20.8 5.2 2.3 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER23088.1 - 0.00031 20.3 13.3 0.0012 18.4 9.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER23088.1 - 0.00094 18.8 15.0 0.01 15.5 10.6 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EER23088.1 - 0.022 14.2 4.4 0.035 13.6 3.1 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EER23088.1 - 0.034 13.7 12.0 0.037 13.6 1.0 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EER23088.1 - 0.15 12.0 15.9 1.1 9.2 11.0 2.7 1 1 0 1 1 1 0 FANCL C-terminal domain Opy2 PF09463.5 EER23088.1 - 0.37 10.9 10.5 3.7 7.7 4.9 2.2 2 0 0 2 2 2 0 Opy2 protein zf-C3HC4_4 PF15227.1 EER23088.1 - 0.46 10.4 13.4 0.43 10.5 7.2 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 EER23088.1 - 0.92 9.3 12.0 7.1 6.5 4.2 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-RING-like PF08746.6 EER23088.1 - 1 9.3 11.3 4.7 7.2 7.8 2.1 1 1 0 1 1 1 0 RING-like domain RecR PF02132.10 EER23088.1 - 1.2 8.6 6.7 4.7 6.7 0.3 3.0 3 0 0 3 3 3 0 RecR protein PHD PF00628.24 EER23088.1 - 2.7 7.7 15.8 3.9 7.2 9.7 2.2 1 1 0 1 1 1 0 PHD-finger zf-HIT PF04438.11 EER23088.1 - 4 7.1 9.5 3.1 7.5 3.7 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-HC5HC2H PF13771.1 EER23088.1 - 4.6 7.4 11.5 25 5.0 7.7 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain RINGv PF12906.2 EER23088.1 - 4.9 7.2 13.4 12 6.0 8.6 2.2 1 1 1 2 2 2 0 RING-variant domain zf-HC5HC2H_2 PF13832.1 EER23088.1 - 5.7 6.9 10.1 26 4.8 7.0 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain Kinesin PF00225.18 EER23090.1 - 4.1e-109 364.3 0.3 8.5e-109 363.2 0.2 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bind PF13931.1 EER23090.1 - 2.4e-05 24.5 0.5 2.4e-05 24.5 0.3 4.7 3 1 1 4 4 4 1 Kinesin-associated microtubule-binding UPF0183 PF03676.9 EER23091.1 - 2.4e-42 144.9 0.0 2.2e-30 105.5 0.0 4.0 4 0 0 4 4 4 4 Uncharacterised protein family (UPF0183) tRNA-synt_1 PF00133.17 EER23092.1 - 3.4e-169 563.6 0.0 4.4e-169 563.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EER23092.1 - 1.4e-21 76.6 0.1 1.8e-13 49.9 0.0 3.9 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EER23092.1 - 3e-20 72.5 0.1 6.7e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EER23092.1 - 0.00012 21.5 0.9 0.00031 20.2 0.6 1.7 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EER23092.1 - 0.012 14.7 0.0 4.6 6.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EER23092.1 - 0.028 13.7 0.0 0.051 12.8 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 Bac_rhodopsin PF01036.13 EER23093.1 - 8.4e-37 126.6 22.7 1e-36 126.3 15.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein YibE_F PF07907.6 EER23093.1 - 0.00073 18.7 8.4 0.00073 18.7 5.8 2.1 2 0 0 2 2 2 2 YibE/F-like protein RPEL PF02755.10 EER23094.1 - 3.1e-26 89.9 17.6 1.2e-09 37.1 0.9 3.6 3 1 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.1 EER23094.1 - 0.019 15.2 0.1 0.19 11.9 0.0 1.9 1 1 1 2 2 2 0 PPIC-type PPIASE domain CCT_2 PF09425.5 EER23094.1 - 0.16 11.5 0.3 0.16 11.5 0.2 2.4 2 0 0 2 2 2 0 Divergent CCT motif CP12 PF02672.10 EER23094.1 - 0.9 10.0 3.5 24 5.4 0.1 2.7 3 0 0 3 3 3 0 CP12 domain MCPVI PF02993.9 EER23094.1 - 1 9.4 3.1 0.93 9.5 0.7 1.7 1 1 0 1 1 1 0 Minor capsid protein VI Translin PF01997.11 EER23095.1 - 4.7e-71 238.5 0.0 5.5e-71 238.2 0.0 1.0 1 0 0 1 1 1 1 Translin family Fungal_trans PF04082.13 EER23096.1 - 7.6e-19 67.5 2.4 1.6e-18 66.5 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER23096.1 - 2.5e-06 27.3 12.3 4.3e-06 26.5 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans PF05007.8 EER23097.1 - 1e-75 254.7 11.3 1e-75 254.7 7.9 1.8 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EER23097.1 - 9.8e-14 51.0 1.2 9.8e-14 51.0 0.8 2.2 1 1 0 2 2 2 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EER23097.1 - 3.6e-06 26.6 17.9 3.6e-06 26.6 12.4 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF2029) F-box-like PF12937.2 EER23098.1 - 0.0017 18.0 0.0 0.0063 16.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like AMP-binding PF00501.23 EER23099.1 - 7.3e-62 209.0 0.0 8.7e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER23099.1 - 2e-11 44.6 0.1 6.3e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH PF00378.15 EER23100.1 - 1.5e-27 96.3 0.0 1.7e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Fungal_trans PF04082.13 EER23101.1 - 4.5e-16 58.5 0.0 6.6e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER23101.1 - 0.0023 17.7 13.0 0.0039 17.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain cIII PF08134.6 EER23101.1 - 0.051 13.1 0.0 5.5 6.6 0.0 2.7 2 0 0 2 2 2 0 cIII protein family SQS_PSY PF00494.14 EER23102.1 - 2.5e-41 141.7 0.0 5.8e-41 140.5 0.0 1.6 2 0 0 2 2 2 1 Squalene/phytoene synthase DnaJ-X PF14308.1 EER23103.1 - 2.5e-75 252.2 6.6 2.5e-75 252.2 4.5 2.8 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EER23103.1 - 7.5e-28 96.0 0.6 2.7e-27 94.2 0.4 2.1 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.14 EER23103.1 - 0.015 14.6 0.7 0.033 13.5 0.5 1.5 1 0 0 1 1 1 0 Probable transposase LEM PF03020.10 EER23103.1 - 0.071 12.5 0.1 0.19 11.1 0.1 1.8 1 0 0 1 1 1 0 LEM domain HNH_2 PF13391.1 EER23105.1 - 2.7e-13 49.4 0.8 1.7e-12 46.9 0.2 2.4 2 0 0 2 2 2 1 HNH endonuclease APG6 PF04111.7 EER23106.1 - 2.1e-118 394.9 0.0 2.7e-118 394.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Selenoprotein_S PF06936.6 EER23106.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Selenoprotein S (SelS) NTR2 PF15458.1 EER23107.1 - 3.4e-22 78.9 0.7 5.6e-22 78.2 0.5 1.4 1 1 0 1 1 1 1 Nineteen complex-related protein 2 DUF1918 PF08940.6 EER23108.1 - 0.00038 19.7 0.1 1.6 8.1 0.0 4.2 3 0 0 3 3 3 2 Domain of unknown function (DUF1918) I-set PF07679.11 EER23108.1 - 0.0075 16.1 0.0 13 5.7 0.0 4.5 4 0 0 4 4 4 1 Immunoglobulin I-set domain Nrap PF03813.9 EER23109.1 - 2.2e-290 965.6 0.0 2.5e-290 965.3 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Cys_Met_Meta_PP PF01053.15 EER23110.1 - 3.5e-32 111.1 0.0 4.8e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EER23110.1 - 0.009 14.9 0.0 0.017 14.0 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II MRP-L20 PF12824.2 EER23112.1 - 1.8e-57 193.8 5.5 2e-57 193.7 3.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Peptidase_M20 PF01546.23 EER23113.1 - 1.4e-30 106.2 0.0 2e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EER23113.1 - 1.6e-14 53.6 0.0 2.8e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain SMC_N PF02463.14 EER23114.1 - 4.1e-26 91.5 0.0 1.4e-25 89.8 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EER23114.1 - 2.7e-09 37.6 22.2 2.7e-09 37.6 15.4 5.1 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EER23114.1 - 1.7e-08 34.8 2.5 3.4e-05 23.9 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EER23114.1 - 0.00072 18.7 0.1 0.00072 18.7 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EER23114.1 - 0.00077 18.9 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EER23114.1 - 0.0012 18.7 0.0 0.0035 17.2 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EER23114.1 - 0.0012 17.4 2.4 0.0012 17.4 1.7 5.3 3 2 1 5 5 5 3 AAA domain ABC_tran PF00005.22 EER23114.1 - 0.15 12.3 0.1 0.15 12.3 0.1 4.9 3 2 0 3 3 3 0 ABC transporter DEAD PF00270.24 EER23115.1 - 6.9e-42 142.8 0.1 1e-41 142.2 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER23115.1 - 4.5e-24 84.1 0.1 8.9e-24 83.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EER23115.1 - 0.019 14.0 0.1 0.046 12.7 0.0 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Mito_carr PF00153.22 EER23116.1 - 2.8e-41 139.1 7.5 1.1e-16 60.3 0.1 4.9 4 1 1 5 5 5 5 Mitochondrial carrier protein RF-1 PF00472.15 EER23117.1 - 5.9e-32 109.8 1.5 1.1e-31 108.9 1.1 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EER23117.1 - 2.3e-27 94.9 0.0 9.2e-27 93.0 0.0 2.0 2 0 0 2 2 2 1 PCRF domain DUF3723 PF12520.3 EER23118.1 - 5.1e-126 421.1 2.5 8.4e-126 420.4 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Ph1570 PF09638.5 EER23118.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Ph1570 protein APH PF01636.18 EER23119.1 - 1.9e-08 34.3 0.0 5.3e-08 32.8 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER23119.1 - 0.075 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase DnaJ PF00226.26 EER23120.1 - 8.9e-25 86.2 1.8 8.9e-25 86.2 1.3 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EER23120.1 - 8.1e-19 67.0 2.6 2.4e-09 36.7 0.0 5.6 6 1 1 7 7 7 3 TPR repeat TPR_1 PF00515.23 EER23120.1 - 3.8e-17 61.0 0.0 4.7e-06 25.9 0.0 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EER23120.1 - 4.1e-14 51.2 0.6 0.0007 19.3 0.0 7.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 EER23120.1 - 5e-13 48.7 4.6 0.0004 20.1 0.0 5.0 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EER23120.1 - 6.6e-13 48.0 4.2 0.12 13.0 0.0 7.3 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EER23120.1 - 2e-12 47.4 4.3 0.0073 16.9 0.5 5.8 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EER23120.1 - 1.4e-09 37.0 0.0 0.024 14.3 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 EER23120.1 - 7.3e-09 35.5 1.2 0.64 10.6 0.0 7.6 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EER23120.1 - 7.2e-08 32.2 2.7 0.3 11.0 0.0 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EER23120.1 - 6.4e-07 29.6 0.1 0.015 15.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER23120.1 - 7.1e-06 25.8 0.1 0.011 15.8 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EER23120.1 - 0.00025 21.1 1.5 3.3 7.9 0.0 4.5 4 2 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EER23120.1 - 0.00076 19.1 0.0 3 7.8 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat RPT PF13446.1 EER23120.1 - 0.055 12.8 0.1 0.54 9.6 0.0 2.6 3 0 0 3 3 3 0 A repeated domain in UCH-protein HEPN PF05168.9 EER23120.1 - 0.061 13.2 3.3 4.9 7.0 0.6 2.9 2 0 0 2 2 2 0 HEPN domain PCMT PF01135.14 EER23121.1 - 1.3e-61 207.7 0.0 2.7e-61 206.7 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EER23121.1 - 1.8e-08 34.9 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER23121.1 - 6e-07 29.1 0.0 8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EER23121.1 - 6.3e-05 22.6 0.0 9.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER23121.1 - 0.00024 20.8 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER23121.1 - 0.00044 20.2 0.0 0.00066 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EER23121.1 - 0.0073 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 EER23121.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EER23121.1 - 0.018 15.4 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EER23121.1 - 0.02 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase RrnaAD PF00398.15 EER23121.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 EER23121.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EER23121.1 - 0.13 13.1 0.0 0.38 11.6 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Pkinase PF00069.20 EER23122.1 - 1.7e-41 142.1 0.0 8.3e-38 130.0 0.0 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER23122.1 - 2.7e-08 33.2 0.0 0.0012 18.0 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EER23122.1 - 0.0013 18.5 0.5 0.022 14.4 0.3 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EER23122.1 - 0.018 14.0 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Cnd1 PF12717.2 EER23123.1 - 1.2e-55 188.1 5.0 2.6e-51 173.9 0.7 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EER23123.1 - 9.5e-55 184.8 0.5 9.5e-55 184.8 0.3 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EER23123.1 - 1.7e-09 37.7 5.6 5.8e-05 23.2 0.0 5.2 3 2 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EER23123.1 - 2.6e-07 30.1 9.0 0.2 11.8 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat DUF2435 PF10363.4 EER23123.1 - 0.00026 20.8 0.1 1.1 9.2 0.0 4.2 3 1 1 4 4 4 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EER23123.1 - 0.0068 16.8 9.1 0.18 12.3 0.0 5.2 6 0 0 6 6 6 1 HEAT-like repeat Cnd3 PF12719.2 EER23123.1 - 0.19 10.6 6.6 0.14 11.0 1.0 3.2 2 2 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain DUF4574 PF15141.1 EER23123.1 - 0.21 11.3 1.6 0.52 10.0 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4574) Oxysterol_BP PF01237.13 EER23124.1 - 1.4e-51 175.0 0.0 3.6e-51 173.7 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein OTU PF02338.14 EER23125.1 - 1.7e-12 48.0 0.0 2.9e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease UN_NPL4 PF11543.3 EER23125.1 - 0.027 14.7 0.0 0.072 13.3 0.0 1.8 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Peptidase_C65 PF10275.4 EER23125.1 - 0.11 11.8 0.0 0.57 9.4 0.0 1.9 1 1 1 2 2 2 0 Peptidase C65 Otubain Bromodomain PF00439.20 EER23126.1 - 8.3e-39 131.3 5.0 2.8e-20 72.0 0.1 3.1 3 0 0 3 3 3 2 Bromodomain BAH PF01426.13 EER23126.1 - 2.9e-18 65.7 0.5 5.8e-18 64.7 0.3 1.5 1 0 0 1 1 1 1 BAH domain zf-CCCH PF00642.19 EER23127.1 - 1.9e-10 40.1 9.7 8.8e-06 25.2 1.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EER23127.1 - 3 7.9 16.0 7.3 6.7 2.9 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Sel1 PF08238.7 EER23128.1 - 5e-19 68.3 21.6 2.1e-07 31.3 0.0 6.7 6 0 0 6 6 6 4 Sel1 repeat TPR_11 PF13414.1 EER23128.1 - 0.0067 16.0 0.2 0.0067 16.0 0.2 2.8 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EER23128.1 - 0.043 13.4 4.3 0.098 12.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EER23128.1 - 0.58 10.2 7.2 1.5 8.9 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.1 EER23129.1 - 7.3e-57 191.9 0.0 1.5e-56 190.9 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EER23129.1 - 2.9e-46 157.0 0.1 1.6e-45 154.6 0.1 2.0 1 1 0 1 1 1 1 DEAD_2 Cas_Csa4 PF09703.5 EER23129.1 - 0.0073 15.3 0.2 0.033 13.1 0.0 2.1 3 0 0 3 3 3 1 CRISPR-associated protein (Cas_Csa4) ResIII PF04851.10 EER23129.1 - 0.0073 16.1 0.1 5.4 6.8 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EER23129.1 - 0.017 15.2 0.1 0.94 9.6 0.2 2.6 2 0 0 2 2 2 0 AAA domain Ribosomal_L18e PF00828.14 EER23130.1 - 1.8e-35 122.1 0.0 2.3e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ectatomin PF06457.6 EER23131.1 - 0.084 12.5 2.8 2.6 7.8 0.0 2.9 3 1 0 3 3 3 0 Ectatomin DUF3328 PF11807.3 EER23132.1 - 1.5e-44 152.2 2.3 1.9e-44 151.9 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Abhydrolase_6 PF12697.2 EER23133.1 - 4.1e-08 33.3 0.0 5.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER23133.1 - 2.1e-07 30.7 0.0 4e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PLDc PF00614.17 EER23135.1 - 2.1e-16 59.1 0.6 1.6e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EER23135.1 - 4.6e-13 49.0 0.0 9.2e-08 31.8 0.0 3.0 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EER23135.1 - 1.5e-09 37.5 0.2 6.4e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 PX domain DNase_NucA_NucB PF14040.1 EER23136.1 - 6.9e-13 48.7 1.7 1.1e-12 48.1 0.0 2.2 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB AA_permease PF00324.16 EER23137.1 - 1.6e-62 211.3 27.4 4.6e-62 209.9 19.0 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER23137.1 - 1e-27 96.7 25.5 1.3e-27 96.4 17.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.4 EER23137.1 - 0.0045 15.6 0.2 0.78 8.2 0.0 2.5 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) Peptidase_S41 PF03572.13 EER23139.1 - 2.5e-08 33.5 0.0 5.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Ras PF00071.17 EER23140.1 - 7.5e-39 132.7 0.0 3.6e-37 127.2 0.0 2.2 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EER23140.1 - 5.8e-12 46.1 0.0 1.5e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EER23140.1 - 0.00069 19.5 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 EER23140.1 - 0.0013 17.9 0.0 0.016 14.4 0.0 2.1 1 1 1 2 2 2 1 ADP-ribosylation factor family PRK PF00485.13 EER23140.1 - 0.1 12.1 0.1 0.3 10.6 0.1 1.8 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2413 PF10310.4 EER23140.1 - 1.5 7.5 11.1 2.2 6.9 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Hid1 PF12722.2 EER23140.1 - 3 5.4 5.2 3.7 5.1 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein QRPTase_C PF01729.14 EER23141.1 - 2.7e-49 166.9 0.0 8.5e-48 162.0 0.0 2.0 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EER23141.1 - 7.5e-24 83.3 0.0 1.5e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Aldose_epim PF01263.15 EER23142.1 - 2.5e-56 191.0 0.1 3e-56 190.7 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Zn_clus PF00172.13 EER23144.1 - 3.3e-08 33.2 16.1 5e-08 32.7 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mto2_bdg PF12808.2 EER23145.1 - 8.1e-27 93.0 32.1 6.9e-20 70.8 12.4 12.5 14 1 1 15 15 15 3 Micro-tubular organiser Mto1 C-term Mto2-binding region Microtub_assoc PF07989.6 EER23145.1 - 4.8e-24 83.9 11.9 4.8e-24 83.9 8.2 8.1 9 1 1 10 10 10 2 Microtubule associated Reo_sigmaC PF04582.7 EER23145.1 - 0.00016 20.9 5.1 0.00016 20.9 3.5 4.9 4 2 1 5 5 5 2 Reovirus sigma C capsid protein Sec7 PF01369.15 EER23146.1 - 1.9e-24 86.3 0.0 6e-22 78.2 0.0 2.7 2 1 1 3 3 3 2 Sec7 domain PH_9 PF15410.1 EER23146.1 - 3.1e-19 69.2 0.1 3e-18 66.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain UNC-50 PF05216.8 EER23147.1 - 7.8e-63 211.7 1.5 1.2e-62 211.1 1.0 1.2 1 0 0 1 1 1 1 UNC-50 family PP28 PF10252.4 EER23149.1 - 1.2e-32 111.7 16.5 1.2e-32 111.7 11.4 3.4 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 MFS_1 PF07690.11 EER23151.1 - 4e-22 78.3 62.6 5.1e-21 74.7 28.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LETM1 PF07766.8 EER23152.1 - 4.6e-05 22.6 0.3 0.029 13.3 0.0 2.3 2 0 0 2 2 2 2 LETM1-like protein PAP_assoc PF03828.14 EER23153.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EER23153.1 - 0.063 13.6 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Glyco_transf_20 PF00982.16 EER23154.1 - 1.1e-152 508.8 0.0 1.7e-152 508.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EER23154.1 - 7.7e-89 296.6 0.0 1.3e-88 295.8 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EER23154.1 - 2.1e-06 27.4 0.0 0.0073 15.9 0.0 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EER23154.1 - 0.009 16.2 0.1 0.097 12.8 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acetyltransf_1 PF00583.19 EER23155.1 - 1e-15 57.4 0.0 1.9e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EER23155.1 - 2e-07 30.6 0.0 1.2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EER23155.1 - 2.9e-07 30.6 0.0 4.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER23155.1 - 2e-06 27.8 0.0 3.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER23155.1 - 3e-05 24.0 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EER23155.1 - 0.00053 19.8 0.0 0.00077 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER23155.1 - 0.00055 19.7 0.0 0.0014 18.4 0.0 1.6 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EER23155.1 - 0.005 17.0 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ZZ PF00569.12 EER23156.1 - 5.6e-20 70.6 51.6 1.4e-06 27.6 3.0 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type Btz PF09405.5 EER23157.1 - 3e-27 95.2 1.5 3e-27 95.2 1.0 1.8 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.17 EER23158.1 - 1.9e-22 78.6 0.0 4.4e-13 48.6 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER23158.1 - 1.3e-20 73.1 0.0 5e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER23158.1 - 7.1e-05 22.5 0.0 0.4 10.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2839 PF10999.3 EER23158.1 - 0.026 14.5 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2839) Ino80_Iec3 PF14612.1 EER23159.1 - 1.4e-82 277.2 0.0 2.1e-82 276.6 0.0 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF3117 PF11314.3 EER23159.1 - 0.077 12.5 0.6 0.18 11.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3117) Transferase PF02458.10 EER23162.1 - 8.7e-24 83.7 0.0 1e-21 76.8 0.0 2.0 2 0 0 2 2 2 2 Transferase family FAD_binding_4 PF01565.18 EER23163.1 - 7.6e-18 64.3 0.7 1.7e-17 63.1 0.5 1.6 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EER23163.1 - 3.7e-10 39.5 0.8 8e-10 38.4 0.1 2.0 2 0 0 2 2 2 1 Berberine and berberine like ECR1_N PF14382.1 EER23164.1 - 2.1e-08 33.2 0.1 5.1e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EER23164.1 - 0.00084 19.2 0.1 0.012 15.5 0.1 2.4 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Oxysterol_BP PF01237.13 EER23165.1 - 4.2e-119 397.1 0.0 7.2e-119 396.4 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EER23165.1 - 5.8e-39 132.0 0.1 1.4e-38 130.8 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EER23165.1 - 0.0013 18.8 0.0 0.0033 17.6 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EER23165.1 - 0.1 12.8 5.1 0.094 12.9 0.4 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain MFS_1 PF07690.11 EER23167.1 - 3.7e-46 157.4 34.6 3.7e-46 157.4 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EER23167.1 - 0.076 11.0 6.8 0.66 7.9 0.5 3.1 2 2 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TPMT PF05724.6 EER23168.1 - 2.8e-29 102.1 0.0 6.9e-29 100.8 0.0 1.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 EER23168.1 - 0.00086 18.9 0.0 0.0025 17.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER23168.1 - 0.0018 18.2 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER23168.1 - 0.0057 16.9 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EER23168.1 - 0.024 14.7 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EER23168.1 - 0.027 14.2 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain N2227 PF07942.7 EER23168.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein OTU PF02338.14 EER23169.1 - 5e-15 56.1 0.4 3.9e-14 53.2 0.0 2.4 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EER23169.1 - 2.4e-05 23.8 0.0 0.091 12.0 0.0 2.4 1 1 1 2 2 2 2 Peptidase C65 Otubain Virul_Fac PF10139.4 EER23169.1 - 0.083 10.8 4.1 0.092 10.6 2.9 1.1 1 0 0 1 1 1 0 Putative bacterial virulence factor DUF3275 PF11679.3 EER23169.1 - 0.26 10.8 4.1 0.46 10.0 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF2890 PF11081.3 EER23169.1 - 0.82 9.6 8.5 1.4 8.9 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) adh_short PF00106.20 EER23170.1 - 2.6e-27 95.7 0.0 4.6e-27 94.9 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER23170.1 - 6.2e-26 91.6 0.0 7.5e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER23170.1 - 1.3e-09 38.0 0.0 2.3e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EER23170.1 - 0.087 11.9 0.0 0.19 10.8 0.0 1.7 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 EER23170.1 - 0.09 11.8 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EER23170.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Trehalase PF01204.13 EER23172.1 - 1.4e-190 634.3 0.0 1.6e-190 634.0 0.0 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EER23172.1 - 2.8e-18 64.8 0.1 4.4e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 EER23172.1 - 0.012 15.5 0.0 5.1 7.0 0.0 2.9 3 0 0 3 3 3 0 Ribbon-helix-helix domain Amidase PF01425.16 EER23173.1 - 1.6e-21 76.7 0.2 3.5e-17 62.3 0.0 2.2 1 1 1 2 2 2 2 Amidase Stig1 PF04885.8 EER23174.1 - 8.5e-22 77.8 116.6 3.7e-07 30.4 10.8 6.0 1 1 3 5 5 5 5 Stigma-specific protein, Stig1 ICL PF00463.16 EER23175.1 - 3.1e-288 956.2 2.4 3.5e-288 956.0 1.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EER23175.1 - 1.6e-12 47.1 1.2 6.1e-12 45.2 0.0 2.2 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Fungal_trans PF04082.13 EER23176.1 - 2.3e-21 75.8 1.0 4.5e-21 74.8 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EER23176.1 - 3.6e-06 26.9 10.2 0.015 15.5 2.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EER23176.1 - 0.0054 17.0 13.0 0.028 14.7 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ank_2 PF12796.2 EER23177.1 - 1.4e-18 67.0 1.0 1.9e-09 37.7 0.1 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER23177.1 - 2.1e-17 63.1 0.2 0.0049 17.3 0.0 5.7 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EER23177.1 - 4e-15 54.7 0.0 0.0023 17.6 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EER23177.1 - 5.1e-12 45.6 1.1 0.019 15.2 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER23177.1 - 4.4e-11 41.8 0.0 0.056 13.6 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat F-box-like PF12937.2 EER23177.1 - 0.00019 21.0 0.1 0.00034 20.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like DUF4265 PF14085.1 EER23177.1 - 0.047 13.4 0.0 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) F-box PF00646.28 EER23178.1 - 0.0048 16.5 0.2 0.018 14.7 0.1 1.9 1 0 0 1 1 1 1 F-box domain G_glu_transpept PF01019.16 EER23179.1 - 6.8e-145 483.4 0.0 7.8e-145 483.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Pkinase PF00069.20 EER23180.1 - 1.5e-70 237.3 0.0 1.9e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23180.1 - 1.3e-29 103.0 0.0 2.1e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER23180.1 - 0.017 14.8 0.2 0.073 12.7 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EER23180.1 - 0.092 11.8 0.0 0.25 10.3 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.26 EER23181.1 - 2.3e-07 30.4 0.1 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EER23181.1 - 1.8e-06 27.7 0.2 3.4e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 Pam16 DUF3918 PF13056.1 EER23181.1 - 0.043 13.1 1.7 0.043 13.1 1.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Ribosomal_L24e PF01246.15 EER23182.1 - 3e-26 91.0 2.1 7.5e-26 89.7 1.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-C2H2_4 PF13894.1 EER23184.1 - 0.0075 16.5 1.7 0.026 14.8 1.2 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EER23184.1 - 0.024 14.9 3.8 0.075 13.4 2.6 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1390 PF07150.6 EER23184.1 - 4 6.7 12.5 7 5.9 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) SnoaL PF07366.7 EER23185.1 - 0.0041 16.6 0.1 0.0082 15.7 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EER23185.1 - 0.014 15.7 0.0 0.039 14.3 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain Methyltransf_16 PF10294.4 EER23186.1 - 7.1e-06 25.5 0.0 0.00019 20.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 EER23186.1 - 0.0025 18.3 0.0 0.0051 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER23187.1 - 1.6e-18 67.2 0.1 2.6e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER23187.1 - 1.1e-11 44.5 0.0 1.3e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EER23187.1 - 1.2e-07 31.7 0.0 2.9e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER23187.1 - 2.3e-06 27.4 0.1 1.2e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER23187.1 - 5.9e-05 23.4 0.1 0.00013 22.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER23187.1 - 0.00052 20.3 0.0 0.0016 18.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23187.1 - 0.00056 20.3 0.4 0.0061 17.0 0.3 2.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EER23187.1 - 0.0015 17.9 0.0 0.0035 16.7 0.0 1.5 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.9 EER23187.1 - 0.17 11.2 0.0 0.35 10.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF4611 PF15387.1 EER23187.1 - 4.4 7.5 9.7 0.14 12.3 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DSPc PF00782.15 EER23188.1 - 1e-24 86.6 0.0 2.8e-22 78.7 0.0 2.3 1 1 1 2 2 2 2 Dual specificity phosphatase, catalytic domain Aminotran_3 PF00202.16 EER23189.1 - 2.5e-54 184.4 0.0 3.3e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DegT_DnrJ_EryC1 PF01041.12 EER23189.1 - 0.019 13.9 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EER23189.1 - 0.11 11.6 0.0 0.45 9.6 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase FMN_bind_2 PF04299.7 EER23191.1 - 1.5e-53 180.7 0.0 1.8e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Hemopexin PF00045.14 EER23193.1 - 9.3e-13 47.6 15.9 0.0012 18.5 0.2 5.1 3 3 1 4 4 4 4 Hemopexin Epimerase PF01370.16 EER23194.1 - 7.9e-19 68.0 0.0 2.2e-18 66.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EER23194.1 - 6.3e-13 48.0 0.0 9.3e-13 47.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EER23194.1 - 1.2e-12 47.2 0.0 2.6e-12 46.1 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EER23194.1 - 1.5e-11 44.6 0.6 3.5e-11 43.4 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EER23194.1 - 8.5e-11 42.0 0.0 1.7e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER23194.1 - 1.5e-06 28.0 0.0 2.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EER23194.1 - 0.00021 20.3 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EER23194.1 - 0.0006 19.1 0.1 0.0028 16.9 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EER23194.1 - 0.002 17.0 0.1 0.041 12.7 0.1 2.6 2 1 0 2 2 2 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EER23194.1 - 0.07 12.0 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DSBA PF01323.15 EER23195.1 - 3.2e-35 121.4 0.0 3.8e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EER23195.1 - 0.003 17.5 0.0 0.0047 16.9 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Zn_clus PF00172.13 EER23198.1 - 5.5e-09 35.8 7.6 1.3e-08 34.5 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EER23198.1 - 2.9e-05 23.0 0.0 7.5e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain KH_1 PF00013.24 EER23199.1 - 2.1e-38 129.7 9.7 5.3e-16 58.0 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EER23199.1 - 3.7e-27 93.4 12.2 8.5e-12 44.4 1.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EER23199.1 - 1.1e-10 40.9 7.4 0.0018 17.7 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EER23199.1 - 1.6e-08 34.0 5.1 0.07 12.7 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EER23199.1 - 0.00033 20.4 4.6 0.19 11.5 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EER23199.1 - 0.095 12.1 0.2 19 4.7 0.0 3.2 3 0 0 3 3 3 0 dUTPase ADH_N PF08240.7 EER23200.1 - 1.5e-30 105.1 0.5 3.2e-30 104.0 0.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER23200.1 - 3.6e-19 68.6 0.0 5.7e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EER23200.1 - 0.00073 19.1 0.1 0.0016 18.0 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Acetyltransf_1 PF00583.19 EER23201.1 - 2.2e-19 69.2 0.0 3.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER23201.1 - 8.2e-13 48.3 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER23201.1 - 2.1e-11 43.9 0.0 2.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER23201.1 - 6.7e-11 41.7 0.1 1.1e-10 41.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EER23201.1 - 4.9e-09 36.4 0.0 6.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER23201.1 - 2.1e-07 30.8 0.0 3.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EER23201.1 - 4.2e-07 29.9 0.0 7.7e-07 29.1 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER23201.1 - 4.3e-06 26.7 0.1 5.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER23201.1 - 0.00016 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.2 EER23201.1 - 0.00093 18.1 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase DUF3749 PF12568.3 EER23201.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4476 PF14771.1 EER23203.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) Mis14 PF08641.7 EER23204.1 - 9.9e-25 87.2 0.2 2.1e-24 86.1 0.1 1.6 1 0 0 1 1 1 1 Kinetochore protein Mis14 like CRAL_TRIO PF00650.15 EER23205.1 - 7.9e-37 126.1 0.0 1.1e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EER23205.1 - 3.3e-09 36.7 0.2 3.3e-09 36.7 0.1 2.5 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EER23205.1 - 6.6e-05 22.8 0.0 0.00017 21.5 0.0 1.6 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.14 EER23207.1 - 6.2e-54 182.6 0.6 1.6e-53 181.3 0.0 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EER23207.1 - 8.5e-32 109.7 7.1 8.5e-32 109.7 4.9 2.4 2 0 0 2 2 2 1 RasGAP C-terminus DUF1647 PF07801.6 EER23207.1 - 0.056 12.9 2.1 0.089 12.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) DUF972 PF06156.8 EER23207.1 - 1.8 8.9 12.7 2.3 8.6 2.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DNA_pol_A_exo1 PF01612.15 EER23208.1 - 3.6e-39 134.0 0.1 1.1e-38 132.4 0.1 1.8 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 EER23208.1 - 1.8e-25 89.0 0.1 4.2e-25 87.8 0.1 1.7 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EER23208.1 - 2.1e-10 40.1 0.0 4.6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Myb_DNA-binding PF00249.26 EER23210.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain Baculo_PEP_C PF04513.7 EER23211.1 - 0.00089 19.0 0.1 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EER23211.1 - 0.06 12.5 0.0 0.07 12.2 0.0 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein SrfB PF07520.6 EER23211.1 - 0.083 10.3 0.0 0.089 10.2 0.0 1.0 1 0 0 1 1 1 0 Virulence factor SrfB DUF2746 PF10874.3 EER23211.1 - 0.12 12.5 0.0 1.9 8.7 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2746) DUF3716 PF12511.3 EER23212.1 - 0.097 12.3 0.9 0.16 11.6 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) NiFeSe_Hases PF00374.14 EER23213.1 - 0.0051 15.6 0.0 0.0077 15.0 0.0 1.2 1 0 0 1 1 1 1 Nickel-dependent hydrogenase Gpi1 PF05024.10 EER23214.1 - 2.2e-63 213.3 8.3 3.4e-63 212.7 5.7 1.3 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) MutS_V PF00488.16 EER23215.1 - 5.8e-95 317.1 0.0 1e-94 316.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EER23215.1 - 2.3e-39 135.3 0.6 4.6e-39 134.3 0.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EER23215.1 - 1.8e-19 70.1 0.2 9.5e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EER23215.1 - 1.3e-17 63.7 1.1 3.5e-17 62.3 0.8 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.15 EER23215.1 - 3.1e-15 56.1 0.0 2.1e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain I HOOK PF05622.7 EER23217.1 - 0.0032 15.3 0.6 0.0037 15.1 0.4 1.0 1 0 0 1 1 1 1 HOOK protein Apolipoprotein PF01442.13 EER23217.1 - 0.0094 15.4 1.2 0.013 14.9 0.9 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Muted PF14942.1 EER23217.1 - 0.012 15.4 1.1 0.015 15.1 0.8 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein GrpE PF01025.14 EER23217.1 - 0.066 12.7 2.4 0.081 12.4 1.6 1.2 1 0 0 1 1 1 0 GrpE ApoLp-III PF07464.6 EER23217.1 - 0.073 13.0 4.2 0.12 12.4 2.9 1.3 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Phasin PF05597.6 EER23217.1 - 0.35 10.6 5.2 2.3 7.9 1.0 2.0 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Borrelia_P83 PF05262.6 EER23217.1 - 0.47 8.6 11.7 0.58 8.3 8.1 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF883 PF05957.8 EER23217.1 - 0.65 10.4 12.6 1.2 9.5 2.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) YbjQ_1 PF01906.12 EER23217.1 - 0.73 10.2 2.4 10 6.6 0.1 2.2 1 1 1 2 2 2 0 Putative heavy-metal-binding Cytochrom_B562 PF07361.6 EER23217.1 - 1.1 9.6 5.9 1.5 9.2 1.5 2.1 1 1 1 2 2 2 0 Cytochrome b562 VSG_B PF13206.1 EER23217.1 - 1.2 8.1 6.0 1.4 7.9 4.1 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain MT0933_antitox PF14013.1 EER23217.1 - 4.5 7.4 10.3 23 5.1 6.8 2.3 1 1 0 1 1 1 0 MT0933-like antitoxin protein ATP-synt_B PF00430.13 EER23217.1 - 5.3 6.8 9.9 9.6 6.0 0.4 2.0 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) ISG65-75 PF11727.3 EER23217.1 - 5.7 5.8 9.6 10 5.1 6.2 1.6 1 1 0 1 1 1 0 Invariant surface glycoprotein Frag1 PF10277.4 EER23218.1 - 1.1e-43 149.1 4.2 1.1e-43 149.1 2.9 2.5 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family DUF3464 PF11947.3 EER23218.1 - 2.5 7.5 5.8 1.1 8.7 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) U3_assoc_6 PF08640.6 EER23219.1 - 3e-30 103.7 1.0 3e-29 100.6 0.5 2.2 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EER23219.1 - 8.5e-05 22.8 0.4 0.6 10.8 0.2 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EER23219.1 - 0.0015 17.4 0.1 0.0022 16.9 0.1 1.2 1 0 0 1 1 1 1 NRDE-2, necessary for RNA interference RF-1 PF00472.15 EER23220.1 - 2.4e-17 62.7 0.6 4e-17 62.0 0.4 1.3 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 EER23220.1 - 0.0028 17.7 0.0 0.0046 17.0 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein RRM_1 PF00076.17 EER23221.1 - 1.5e-10 40.5 0.0 2.5e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER23221.1 - 3.1e-09 36.6 0.0 7.4e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER23221.1 - 0.0008 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Urb2 PF10441.4 EER23221.1 - 0.14 11.7 0.5 6.3 6.3 0.0 2.6 2 0 0 2 2 2 0 Urb2/Npa2 family COX6B PF02297.12 EER23222.1 - 6.7e-24 83.6 2.4 8.2e-24 83.4 1.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Prolamin_like PF05617.6 EER23222.1 - 0.037 14.1 0.5 0.055 13.6 0.3 1.4 1 1 0 1 1 1 0 Prolamin-like HMG_box_5 PF14887.1 EER23222.1 - 0.044 13.5 0.7 0.087 12.6 0.1 1.7 1 1 1 2 2 2 0 HMG (high mobility group) box 5 Pet191_N PF10203.4 EER23222.1 - 0.14 12.2 1.6 0.32 11.0 1.1 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EER23222.1 - 0.22 11.4 1.8 17 5.4 0.2 2.5 2 0 0 2 2 2 0 CHCH domain SYS1 PF09801.4 EER23223.1 - 5e-52 175.7 7.7 5.7e-52 175.5 5.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Acyl_transf_3 PF01757.17 EER23223.1 - 0.023 13.5 14.6 0.029 13.1 10.1 1.0 1 0 0 1 1 1 0 Acyltransferase family DUF485 PF04341.7 EER23223.1 - 0.24 11.1 7.0 0.14 11.9 3.2 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF485 COG5 PF10392.4 EER23224.1 - 1.5e-41 141.4 0.5 1.4e-40 138.3 0.0 2.7 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Med17 PF10156.4 EER23224.1 - 0.065 11.5 0.1 2.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Subunit 17 of Mediator complex zf-C2H2_4 PF13894.1 EER23225.1 - 5.6e-06 26.3 12.8 0.00097 19.3 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EER23225.1 - 6.7e-06 26.1 4.0 6.7e-06 26.1 2.8 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EER23225.1 - 2.5e-05 24.3 12.1 0.0089 16.3 1.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type TylF PF05711.6 EER23225.1 - 0.21 10.6 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) CPSF100_C PF13299.1 EER23228.1 - 4.1e-41 140.8 0.9 7.2e-41 140.0 0.0 1.9 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EER23228.1 - 4.1e-29 101.0 0.0 1.5e-28 99.2 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EER23228.1 - 0.00039 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EER23228.1 - 0.012 15.2 0.0 0.053 13.1 0.0 2.0 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily AA_permease_2 PF13520.1 EER23230.1 - 2.5e-54 184.4 45.0 3.1e-54 184.1 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER23230.1 - 1.6e-18 66.2 37.9 2.2e-18 65.8 26.3 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.6 EER23230.1 - 0.82 8.5 5.9 0.41 9.5 0.8 2.3 2 0 0 2 2 2 0 BlaR1 peptidase M56 Sec23_trunk PF04811.10 EER23231.1 - 6e-53 179.6 0.0 1.6e-52 178.2 0.0 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EER23231.1 - 2.2e-27 94.4 0.0 4e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EER23231.1 - 2.6e-17 63.1 0.0 7.1e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EER23231.1 - 4.2e-17 61.4 4.6 8.6e-17 60.4 3.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EER23231.1 - 6e-08 32.2 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Fe-ADH PF00465.14 EER23231.1 - 0.018 13.6 0.1 0.037 12.6 0.1 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase Bys1 PF04681.7 EER23232.1 - 3.2e-05 23.7 0.5 6.6e-05 22.6 0.3 1.5 1 1 0 1 1 1 1 Blastomyces yeast-phase-specific protein Thaumatin PF00314.12 EER23232.1 - 0.0001 21.8 1.6 0.00017 21.0 0.7 1.6 1 1 0 1 1 1 1 Thaumatin family ABC_tran PF00005.22 EER23233.1 - 4.9e-51 172.6 0.2 6.5e-25 88.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC2_membrane PF01061.19 EER23233.1 - 2.1e-47 161.0 34.2 2.1e-26 92.4 10.2 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EER23233.1 - 4.6e-17 62.9 1.6 7.1e-05 22.9 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_25 PF13481.1 EER23233.1 - 1.3e-10 40.9 0.2 0.001 18.5 0.1 3.8 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EER23233.1 - 4.6e-08 33.2 1.1 0.005 16.8 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EER23233.1 - 1e-07 31.2 0.5 0.0047 16.1 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EER23233.1 - 1.1e-07 32.4 0.0 0.0023 18.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EER23233.1 - 5e-07 29.1 0.0 1.1 8.2 0.0 4.1 3 1 1 4 4 4 2 AAA ATPase domain AAA_19 PF13245.1 EER23233.1 - 2.4e-06 27.1 0.9 0.059 13.1 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_17 PF13207.1 EER23233.1 - 2.9e-06 28.0 0.0 0.13 13.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EER23233.1 - 3.4e-06 26.4 1.4 0.071 12.6 0.5 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EER23233.1 - 5.2e-06 26.6 0.0 0.1 12.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EER23233.1 - 7e-06 25.4 1.2 0.1 11.8 0.1 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EER23233.1 - 2e-05 24.3 1.1 0.032 13.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 EER23233.1 - 8.1e-05 22.4 0.0 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EER23233.1 - 0.0001 22.2 0.5 0.094 12.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EER23233.1 - 0.00011 22.5 0.1 0.94 9.7 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 EER23233.1 - 0.00015 21.9 0.1 0.71 10.0 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EER23233.1 - 0.00041 19.8 0.1 0.073 12.5 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EER23233.1 - 0.00046 20.6 0.2 0.37 11.3 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EER23233.1 - 0.00084 18.3 0.0 0.36 9.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 EER23233.1 - 0.0012 18.4 0.0 0.57 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EER23233.1 - 0.0016 18.3 0.9 2.6 8.0 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EER23233.1 - 0.0018 18.1 0.1 0.46 10.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EER23233.1 - 0.0021 17.2 0.4 0.55 9.2 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 EER23233.1 - 0.0025 17.9 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 EER23233.1 - 0.0027 17.1 3.3 0.17 11.3 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EER23233.1 - 0.0036 17.0 0.0 3.7 7.2 0.0 3.6 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EER23233.1 - 0.0066 15.9 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 EER23233.1 - 0.008 15.6 5.1 0.9 8.9 0.1 2.3 2 0 0 2 2 2 2 AAA-like domain MobB PF03205.9 EER23233.1 - 0.0095 15.6 0.8 1.4 8.6 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 EER23233.1 - 0.013 14.8 0.7 2.6 7.2 0.2 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein UPF0079 PF02367.12 EER23233.1 - 0.013 15.1 0.1 7.5 6.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EER23233.1 - 0.017 14.6 0.4 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.6 EER23233.1 - 0.035 13.6 0.0 0.12 11.8 0.0 1.9 1 0 0 1 1 1 0 Plant PDR ABC transporter associated IstB_IS21 PF01695.12 EER23233.1 - 0.036 13.5 0.2 0.42 9.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 EER23233.1 - 0.1 12.5 1.6 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase KAP_NTPase PF07693.9 EER23233.1 - 0.14 11.1 0.0 4.3 6.2 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain PduV-EutP PF10662.4 EER23233.1 - 0.14 11.6 1.0 12 5.4 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 EER23233.1 - 0.3 10.0 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 EER23233.1 - 0.35 10.4 0.6 12 5.3 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.12 EER23233.1 - 6.6 6.4 5.6 21 4.8 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Fungal_trans_2 PF11951.3 EER23234.1 - 3.2e-67 226.7 0.2 4.1e-67 226.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER23234.1 - 1.1e-09 37.9 10.5 2e-09 37.2 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EER23234.1 - 0.39 10.5 6.8 1.1 9.1 4.7 1.8 1 0 0 1 1 1 0 AT hook motif DUF2434 PF10361.4 EER23236.1 - 3.5e-133 443.2 4.8 4.4e-133 442.9 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Gti1_Pac2 PF09729.4 EER23237.1 - 5.4e-51 172.8 1.2 2e-49 167.7 0.8 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family Peptidase_M6 PF05547.6 EER23238.1 - 1.3e-06 26.7 1.1 0.00069 17.7 0.9 2.2 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 FAD_binding_4 PF01565.18 EER23239.1 - 8.7e-18 64.1 0.0 1.4e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain tRNA-synt_2 PF00152.15 EER23240.1 - 2.4e-63 213.9 0.0 3.4e-63 213.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EER23240.1 - 2.4e-07 30.5 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RRM_1 PF00076.17 EER23241.1 - 3.1e-10 39.5 0.0 6.9e-10 38.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER23241.1 - 2.3e-06 27.4 0.0 5.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_PEP_C PF04513.7 EER23241.1 - 0.14 12.0 2.5 0.095 12.5 0.2 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MOZ_SAS PF01853.13 EER23242.1 - 8.8e-55 184.8 0.7 8.4e-54 181.6 0.5 2.0 1 1 0 1 1 1 1 MOZ/SAS family IF2_N PF04760.10 EER23242.1 - 0.085 12.5 0.2 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Cpn60_TCP1 PF00118.19 EER23243.1 - 3.7e-149 497.4 0.1 4.2e-149 497.2 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RSF PF14876.1 EER23243.1 - 0.055 12.2 0.1 0.082 11.6 0.1 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator Nop PF01798.13 EER23244.1 - 6.7e-60 200.7 0.0 1.7e-59 199.3 0.0 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EER23244.1 - 1.4e-25 88.7 0.4 2.7e-25 87.9 0.3 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EER23244.1 - 1.2e-22 79.7 0.0 1.2e-22 79.7 0.0 3.0 3 1 0 3 3 3 1 NOP5NT (NUC127) domain GAGA_bind PF06217.7 EER23244.1 - 0.88 9.4 18.9 1.7 8.5 13.1 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 EER23244.1 - 1.9 8.2 13.6 3.6 7.3 9.5 1.4 1 0 0 1 1 1 0 DDHD domain MIP-T3 PF10243.4 EER23244.1 - 8.5 4.7 44.1 13 4.1 30.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Phage_Mu_Gp45 PF06890.7 EER23245.1 - 0.027 13.9 0.3 0.045 13.1 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein CcmD PF04995.9 EER23245.1 - 0.15 11.8 0.7 0.38 10.5 0.5 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF3767 PF12597.3 EER23246.1 - 2.4e-37 127.2 0.1 4.7e-37 126.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.7 EER23246.1 - 0.071 12.4 0.4 0.094 12.0 0.3 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT DUF1744 PF08490.7 EER23247.1 - 3e-149 496.9 0.2 4.5e-149 496.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EER23247.1 - 9.2e-66 221.9 2.2 2.4e-65 220.5 1.5 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EER23247.1 - 2.3e-21 76.1 0.0 1e-20 74.0 0.0 2.0 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EER23247.1 - 2.9e-09 36.7 0.1 8.5e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EER23247.1 - 1.7e-05 24.7 0.4 0.00017 21.4 0.0 3.0 4 0 0 4 4 4 1 RNase_H superfamily Pkinase PF00069.20 EER23248.1 - 1e-70 237.8 0.0 2.8e-70 236.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23248.1 - 7.1e-30 103.9 0.0 1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER23248.1 - 7e-07 28.4 0.0 1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER23248.1 - 0.00026 20.7 0.1 0.00046 19.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EER23248.1 - 0.001 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EER23248.1 - 0.037 13.3 0.0 0.098 11.9 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL AMMECR1 PF01871.12 EER23249.1 - 7.5e-39 132.5 0.0 1.6e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 AMMECR1 SGT1 PF07093.6 EER23250.1 - 2e-135 452.4 37.3 4.9e-132 441.2 19.9 3.0 1 1 1 2 2 2 2 SGT1 protein Mnd1 PF03962.10 EER23250.1 - 0.057 13.0 9.7 0.18 11.4 6.7 1.9 1 0 0 1 1 1 0 Mnd1 family PACT_coil_coil PF10495.4 EER23251.1 - 5.8e-23 80.6 1.2 2.4e-22 78.6 0.8 2.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Microtub_assoc PF07989.6 EER23251.1 - 1.6e-22 79.0 4.7 1.6e-22 79.0 3.2 9.9 7 3 5 13 13 13 1 Microtubule associated TPR_MLP1_2 PF07926.7 EER23251.1 - 0.00032 20.4 13.2 0.00032 20.4 9.1 10.4 3 3 5 9 9 9 2 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EER23251.1 - 0.0012 18.6 17.3 0.0012 18.6 12.0 15.7 8 4 7 15 15 15 3 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.7 EER23251.1 - 0.0074 15.9 1.6 0.0074 15.9 1.1 13.8 15 1 1 16 16 16 3 Viral A-type inclusion protein repeat TPR_8 PF13181.1 EER23251.1 - 0.018 14.8 0.4 0.094 12.5 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DivIC PF04977.10 EER23251.1 - 0.7 9.4 0.0 0.7 9.4 0.0 15.2 11 3 2 15 15 15 0 Septum formation initiator Reo_sigmaC PF04582.7 EER23251.1 - 6.1 5.9 33.6 0.1 11.7 0.3 6.3 2 1 3 7 7 7 0 Reovirus sigma C capsid protein AAA PF00004.24 EER23252.1 - 2.7e-42 144.0 0.0 5.1e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EER23252.1 - 1.3e-28 98.6 0.0 5.3e-28 96.6 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EER23252.1 - 4.9e-22 77.5 1.7 4.9e-22 77.5 1.2 2.3 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EER23252.1 - 1.1e-06 29.4 0.0 1.1e-05 26.1 0.0 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EER23252.1 - 3.2e-06 26.3 0.0 5.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EER23252.1 - 7.7e-06 26.0 0.1 0.0011 19.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER23252.1 - 2.2e-05 24.1 0.0 8.1e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EER23252.1 - 2.3e-05 23.9 0.0 4.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EER23252.1 - 3.2e-05 23.8 0.0 6.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EER23252.1 - 4.6e-05 23.5 0.0 0.0089 16.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 EER23252.1 - 9.3e-05 22.4 0.0 0.0012 18.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EER23252.1 - 9.6e-05 22.3 0.0 0.0024 17.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EER23252.1 - 0.00014 21.2 0.1 0.18 11.1 0.1 2.8 2 1 1 3 3 3 2 AAA domain DUF815 PF05673.8 EER23252.1 - 0.00015 20.7 0.0 0.00063 18.7 0.0 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EER23252.1 - 0.00023 19.9 0.0 0.00037 19.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EER23252.1 - 0.00046 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EER23252.1 - 0.0049 17.1 0.1 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EER23252.1 - 0.012 15.1 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EER23252.1 - 0.015 14.9 0.0 0.55 9.8 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EER23252.1 - 0.016 14.3 0.0 0.063 12.4 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EER23252.1 - 0.02 14.6 0.0 0.065 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EER23252.1 - 0.022 13.8 0.1 0.16 11.0 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin ResIII PF04851.10 EER23252.1 - 0.031 14.1 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EER23252.1 - 0.039 13.6 0.3 0.35 10.5 0.0 2.3 2 1 1 3 3 3 0 Archaeal ATPase PhoH PF02562.11 EER23252.1 - 0.04 13.1 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EER23252.1 - 0.04 13.0 0.0 4.5 6.3 0.0 2.7 2 1 1 3 3 3 0 KaiC Parvo_NS1 PF01057.12 EER23252.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 USP8_dimer PF08969.6 EER23252.1 - 0.074 13.0 1.1 0.18 11.7 0.8 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain Torsin PF06309.6 EER23252.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_28 PF13521.1 EER23252.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EER23252.1 - 0.21 11.5 0.3 2.8 7.8 0.0 2.2 1 1 1 2 2 2 0 AAA domain TPR_1 PF00515.23 EER23252.1 - 0.65 9.7 4.5 0.18 11.4 0.4 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 EER23253.1 - 5.6e-23 80.7 14.8 7.6e-23 80.3 10.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EER23253.1 - 5.5e-06 26.0 4.9 7.7e-06 25.6 3.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EER23253.1 - 0.0072 15.9 16.9 0.014 14.9 6.5 2.0 1 1 1 2 2 2 1 IncA protein DUF972 PF06156.8 EER23253.1 - 0.008 16.5 10.0 0.36 11.1 0.8 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF972) NPV_P10 PF05531.7 EER23253.1 - 0.01 16.0 11.2 0.29 11.4 0.8 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc24 PF08286.6 EER23253.1 - 0.014 15.0 4.3 0.014 15.0 3.0 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 EER23253.1 - 0.018 14.9 13.7 0.34 10.7 2.6 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin PF02996.12 EER23253.1 - 0.03 13.9 2.1 0.03 13.9 1.4 2.5 2 1 0 2 2 2 0 Prefoldin subunit Ctf8 PF09696.5 EER23253.1 - 0.063 13.0 2.4 0.092 12.5 1.6 1.3 1 0 0 1 1 1 0 Ctf8 ATG16 PF08614.6 EER23253.1 - 0.079 12.7 10.5 0.064 13.0 1.8 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) COG2 PF06148.6 EER23253.1 - 0.12 12.2 6.6 1.3 8.9 0.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IFT46_B_C PF12317.3 EER23253.1 - 0.12 11.6 2.9 0.078 12.3 0.8 1.6 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal DUF4201 PF13870.1 EER23253.1 - 0.13 11.6 9.9 0.35 10.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.3 EER23253.1 - 0.16 11.6 11.4 0.21 11.3 2.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YgaB PF14182.1 EER23253.1 - 0.17 12.1 14.1 0.069 13.3 2.3 2.3 2 0 0 2 2 2 0 YgaB-like protein BLOC1_2 PF10046.4 EER23253.1 - 0.2 11.7 8.7 1.5 8.9 1.5 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Taxilin PF09728.4 EER23253.1 - 0.29 10.1 12.5 0.047 12.7 2.7 2.0 2 0 0 2 2 2 0 Myosin-like coiled-coil protein ERM PF00769.14 EER23253.1 - 0.3 10.5 14.7 0.22 11.0 1.9 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family FlxA PF14282.1 EER23253.1 - 0.38 10.7 21.7 0.19 11.7 3.8 2.2 2 0 0 2 2 2 0 FlxA-like protein Osmo_CC PF08946.5 EER23253.1 - 0.4 10.7 6.0 0.099 12.6 1.3 2.1 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Tropomyosin_1 PF12718.2 EER23253.1 - 0.5 10.2 15.7 2 8.2 1.4 2.0 2 0 0 2 2 2 0 Tropomyosin like Spc7 PF08317.6 EER23253.1 - 0.64 8.6 12.3 0.81 8.2 8.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Dad3 PF08656.5 EER23253.1 - 0.67 9.6 4.5 4 7.1 1.4 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 Lzipper-MIP1 PF14389.1 EER23253.1 - 0.68 10.0 11.7 0.22 11.6 1.5 2.9 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 GrpE PF01025.14 EER23253.1 - 0.73 9.3 12.3 1 8.8 1.7 2.1 2 0 0 2 2 2 0 GrpE DivIC PF04977.10 EER23253.1 - 0.97 8.9 21.1 0.45 10.0 2.0 3.1 2 1 1 3 3 3 0 Septum formation initiator ERp29 PF07749.7 EER23253.1 - 1.1 9.9 5.4 2.7 8.6 3.8 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF3166 PF11365.3 EER23253.1 - 1.2 9.5 8.8 1.7 9.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) TPR_MLP1_2 PF07926.7 EER23253.1 - 1.5 8.5 16.0 3.3 7.4 4.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliD_C PF07195.7 EER23253.1 - 1.6 7.9 8.3 1.5 8.1 3.7 1.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF904 PF06005.7 EER23253.1 - 1.9 8.8 11.2 1.2 9.5 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Cluap1 PF10234.4 EER23253.1 - 2.2 7.4 12.2 0.14 11.3 1.7 2.0 2 0 0 2 2 2 0 Clusterin-associated protein-1 Occludin_ELL PF07303.8 EER23253.1 - 2.5 8.8 9.2 3.6 8.3 1.8 2.1 1 1 1 2 2 2 0 Occludin homology domain TMPIT PF07851.8 EER23253.1 - 3.4 6.6 7.9 4.3 6.3 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4140 PF13600.1 EER23253.1 - 3.8 7.9 12.8 4.9 7.6 0.4 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) U1snRNP70_N PF12220.3 EER23253.1 - 4 7.8 8.1 4.2 7.7 1.2 2.1 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Rootletin PF15035.1 EER23253.1 - 4.4 7.2 12.6 5.2 7.0 4.1 2.3 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Allexi_40kDa PF05549.6 EER23253.1 - 4.4 6.5 5.9 10 5.3 0.6 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF1664 PF07889.7 EER23253.1 - 4.8 6.9 9.0 9.3 6.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 EER23253.1 - 4.9 7.1 17.1 0.48 10.3 1.6 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) APG6 PF04111.7 EER23253.1 - 5.6 5.9 16.0 2.4e+02 0.5 11.1 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 AAA_13 PF13166.1 EER23253.1 - 9.5 4.5 13.7 21 3.4 9.5 1.5 1 1 0 1 1 1 0 AAA domain DUF948 PF06103.6 EER23253.1 - 9.7 6.1 8.6 2.5 8.0 0.5 2.1 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Metalloenzyme PF01676.13 EER23254.1 - 6.1e-73 245.2 0.0 7.1e-73 245.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EER23254.1 - 1.2e-70 237.2 0.0 1.7e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EER23254.1 - 2.4e-09 37.0 0.0 3.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EER23254.1 - 5.8e-06 25.7 0.0 9.8e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.7 EER23254.1 - 0.032 13.8 0.0 0.1 12.2 0.0 1.9 2 0 0 2 2 2 0 PglZ domain Alk_phosphatase PF00245.15 EER23254.1 - 0.092 11.4 0.0 0.38 9.3 0.0 1.8 2 0 0 2 2 2 0 Alkaline phosphatase Med9 PF07544.8 EER23255.1 - 6.3e-24 83.5 0.2 9.3e-24 82.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.7 EER23255.1 - 0.0049 17.2 0.4 0.01 16.1 0.3 1.6 1 0 0 1 1 1 1 SlyX IncA PF04156.9 EER23255.1 - 0.028 14.0 0.1 0.034 13.7 0.1 1.1 1 0 0 1 1 1 0 IncA protein AKNA PF12443.3 EER23255.1 - 0.041 13.9 0.5 0.12 12.4 0.4 1.7 1 1 0 1 1 1 0 AT-hook-containing transcription factor DivIC PF04977.10 EER23255.1 - 0.093 12.2 0.7 0.14 11.6 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator Sec20 PF03908.8 EER23255.1 - 0.098 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Sec20 SNARE PF05739.14 EER23255.1 - 0.099 12.3 1.0 0.18 11.5 0.7 1.4 1 0 0 1 1 1 0 SNARE domain Fib_alpha PF08702.5 EER23255.1 - 0.15 12.1 0.3 0.21 11.7 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Med21 PF11221.3 EER23255.1 - 4.1 7.3 18.3 81 3.1 12.7 2.2 1 1 0 1 1 1 0 Subunit 21 of Mediator complex SHMT PF00464.14 EER23256.1 - 8.9e-211 699.3 0.0 1e-210 699.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EER23256.1 - 0.013 14.6 0.0 0.026 13.6 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.14 EER23256.1 - 0.051 12.3 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V RNA_polI_A34 PF08208.6 EER23257.1 - 1.5e-28 99.8 8.5 1.5e-28 99.8 5.9 3.2 2 1 1 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 Clp1 PF06807.9 EER23258.1 - 8.6e-09 35.4 0.0 0.0017 18.1 0.0 2.5 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EER23258.1 - 3.5e-05 23.5 0.0 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EER23258.1 - 0.00049 20.0 1.3 0.02 14.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER23258.1 - 0.008 17.0 0.0 0.031 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EER23258.1 - 0.0085 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EER23258.1 - 0.021 14.9 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EER23258.1 - 0.065 12.6 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EER23258.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 EER23258.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin Folliculin PF11704.3 EER23259.1 - 4.4e-46 156.5 0.0 6e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport PCI_Csn8 PF10075.4 EER23260.1 - 8.1e-47 158.5 0.0 1.3e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EER23260.1 - 9e-21 74.3 0.1 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PDCD2_C PF04194.8 EER23261.1 - 1.6e-51 174.1 0.0 7.2e-51 172.0 0.0 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Kdo PF06293.9 EER23262.1 - 8.9e-07 28.1 0.1 1.8e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER23262.1 - 5.6e-05 22.9 0.1 0.00044 20.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EER23262.1 - 0.019 14.1 0.0 0.019 14.1 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.15 EER23262.1 - 0.027 14.0 0.5 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.17 EER23262.1 - 0.034 13.5 0.5 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Acyl-CoA_ox_N PF14749.1 EER23263.1 - 5.2e-22 78.4 0.8 9e-22 77.6 0.6 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal ACOX PF01756.14 EER23263.1 - 9e-11 41.4 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EER23263.1 - 9.1e-11 41.1 0.8 2.4e-10 39.7 0.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EER23263.1 - 0.0057 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HBS1_N PF08938.5 EER23263.1 - 0.079 13.0 0.1 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 HBS1 N-terminus DUF1571 PF07608.6 EER23263.1 - 0.13 11.3 0.1 0.41 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1571) ACOX PF01756.14 EER23264.1 - 3.4e-37 127.6 0.0 8.2e-37 126.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EER23264.1 - 1.8e-25 89.6 0.0 8e-25 87.5 0.0 2.1 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EER23264.1 - 8.3e-08 31.6 0.1 2.5e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EER23264.1 - 0.039 14.5 0.0 0.11 13.1 0.0 1.8 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain AA_kinase PF00696.23 EER23265.1 - 0.033 13.7 0.2 0.043 13.3 0.2 1.3 1 0 0 1 1 1 0 Amino acid kinase family Tropomyosin PF00261.15 EER23265.1 - 0.075 12.1 3.1 0.12 11.3 2.2 1.3 1 0 0 1 1 1 0 Tropomyosin Receptor_2B4 PF11465.3 EER23265.1 - 0.083 12.8 0.5 0.14 12.0 0.4 1.3 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Herpes_UL25 PF01499.11 EER23265.1 - 0.1 10.9 0.5 0.12 10.6 0.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3337 PF11816.3 EER23265.1 - 0.18 11.1 1.4 0.34 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) Prenylcys_lyase PF07156.9 EER23267.1 - 1.1e-44 152.8 0.0 2.6e-32 112.1 0.0 2.3 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EER23267.1 - 3.8e-12 46.0 0.0 9.5e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EER23267.1 - 8.3e-09 35.0 0.1 3e-07 29.8 0.0 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EER23267.1 - 8.1e-05 22.4 0.1 0.00077 19.2 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EER23267.1 - 0.0023 16.8 0.0 0.0049 15.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EER23267.1 - 0.0073 16.3 0.1 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER23267.1 - 0.037 13.9 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EER23267.1 - 0.24 10.3 1.3 7 5.4 0.0 2.4 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EER23268.1 - 5.6e-23 82.0 0.0 1.4e-22 80.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER23268.1 - 1.5e-07 31.3 0.1 1.3e-06 28.3 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EER23268.1 - 1.9e-05 24.4 0.0 0.0013 18.4 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EER23268.1 - 0.00039 20.5 0.0 0.023 14.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 EER23268.1 - 0.0021 16.3 0.0 0.013 13.7 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.14 EER23268.1 - 0.0029 16.7 0.0 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EER23268.1 - 0.0066 16.3 0.0 1 9.2 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF2407_C PF13373.1 EER23268.1 - 0.08 12.8 0.0 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain Amidase PF01425.16 EER23269.1 - 1.5e-81 274.4 0.0 1.9e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Glyco_transf_28 PF03033.15 EER23270.1 - 6e-25 87.6 0.0 1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EER23270.1 - 0.00076 18.1 0.0 0.0012 17.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Prefoldin PF02996.12 EER23271.1 - 1.6e-27 95.5 0.1 2.3e-27 95.0 0.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit Methyltransf_25 PF13649.1 EER23272.1 - 1.2e-07 32.0 0.1 2e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER23272.1 - 1.6e-07 30.9 0.0 2.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER23272.1 - 6.9e-07 28.6 0.3 1.1e-06 27.9 0.0 1.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EER23272.1 - 1.5e-06 28.6 0.0 2.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23272.1 - 3.3e-06 27.4 0.1 5.7e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER23272.1 - 2.3e-05 24.3 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER23272.1 - 0.00028 20.3 0.1 0.00043 19.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EER23272.1 - 0.00043 20.8 0.0 0.00065 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EER23272.1 - 0.00085 18.5 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EER23272.1 - 0.0079 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER23272.1 - 0.034 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_4 PF13577.1 EER23273.1 - 0.023 14.5 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_2 PF12680.2 EER23273.1 - 0.024 15.0 0.0 0.032 14.6 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain AMP-binding PF00501.23 EER23274.1 - 1.8e-159 530.6 0.1 4e-79 265.9 0.0 2.4 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EER23274.1 - 3e-77 259.4 0.0 4e-39 134.2 0.0 3.3 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 EER23274.1 - 2.3e-22 79.0 0.0 2.1e-13 50.3 0.0 3.7 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EER23274.1 - 4.5e-13 49.9 0.3 9.5e-05 23.2 0.2 3.4 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Beta-lactamase PF00144.19 EER23275.1 - 2.7e-53 181.1 0.0 3.7e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EER23275.1 - 0.005 16.6 0.0 0.09 12.6 0.0 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3471) Vma12 PF11712.3 EER23276.1 - 2.7e-35 121.1 0.0 3.8e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Amidohydro_1 PF01979.15 EER23277.1 - 3.1e-24 86.2 0.0 9.9e-23 81.3 0.0 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EER23277.1 - 4e-19 69.7 0.0 9.8e-19 68.4 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EER23277.1 - 4.5e-10 39.1 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EER23277.1 - 1.5e-09 37.5 0.0 9.8e-06 25.0 0.0 3.0 3 0 0 3 3 3 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 EER23277.1 - 0.25 10.7 0.0 0.43 10.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 UDP-g_GGTase PF06427.6 EER23278.1 - 7.2e-69 231.2 0.0 1.3e-68 230.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EER23278.1 - 1.8e-05 24.2 0.2 0.00013 21.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 8 PhzC-PhzF PF02567.11 EER23280.1 - 4e-20 72.1 0.5 2.5e-09 36.7 0.1 2.3 2 1 0 2 2 2 2 Phenazine biosynthesis-like protein HSP70 PF00012.15 EER23281.1 - 8.2e-89 298.1 3.9 3.6e-88 296.0 0.3 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EER23281.1 - 5.1e-12 45.0 0.3 9e-12 44.2 0.2 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 EER23281.1 - 1.1e-05 24.4 0.3 7e-05 21.8 0.2 2.0 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; Actin PF00022.14 EER23281.1 - 0.00072 18.0 0.1 0.098 11.0 0.0 2.1 1 1 0 2 2 2 2 Actin FtsA PF14450.1 EER23281.1 - 0.0014 18.4 0.2 2.9 7.7 0.0 3.3 3 0 0 3 3 3 1 Cell division protein FtsA Peripla_BP_6 PF13458.1 EER23281.1 - 0.025 13.9 0.3 0.093 12.0 0.1 1.8 1 1 1 2 2 2 0 Periplasmic binding protein Rpp20 PF12328.3 EER23282.1 - 4.6e-52 175.5 5.4 6.1e-52 175.0 3.8 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EER23282.1 - 1.8e-22 78.6 2.0 3.5e-22 77.7 1.4 1.5 1 0 0 1 1 1 1 Alba DUF4168 PF13767.1 EER23282.1 - 0.82 10.3 3.4 20 5.8 2.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4168) Zip PF02535.17 EER23285.1 - 4.2e-46 157.4 3.1 5.5e-46 157.0 2.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Rogdi_lz PF10259.4 EER23287.1 - 2e-74 250.1 0.0 2.3e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.5 EER23288.1 - 1.6e-28 99.5 0.0 1.4e-27 96.4 0.0 2.4 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 EER23288.1 - 0.00031 20.4 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER23288.1 - 0.0096 16.3 0.0 0.032 14.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23288.1 - 0.16 12.4 0.0 0.73 10.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DASH_Spc19 PF08287.6 EER23289.1 - 5.8e-52 175.3 3.0 7.4e-52 175.0 2.1 1.1 1 0 0 1 1 1 1 Spc19 IFP_35_N PF07334.8 EER23289.1 - 0.042 13.8 2.7 5 7.1 2.1 3.0 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Mur_ligase_M PF08245.7 EER23289.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.4 1 1 0 1 1 1 0 Mur ligase middle domain COG5 PF10392.4 EER23289.1 - 0.42 10.5 5.9 5.9 6.8 0.3 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 ATP-synt_J PF04911.7 EER23290.1 - 1.2e-26 91.8 0.5 1.4e-26 91.7 0.3 1.0 1 0 0 1 1 1 1 ATP synthase j chain Ribosomal_S14 PF00253.16 EER23291.1 - 2.5e-19 68.3 0.2 2e-17 62.2 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein S14p/S29e QLQ PF08880.6 EER23291.1 - 0.24 10.8 0.2 0.24 10.8 0.1 1.9 2 1 0 2 2 2 0 QLQ Arb2 PF09757.4 EER23292.1 - 2.9e-33 114.7 0.0 4.3e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain LRR_8 PF13855.1 EER23293.1 - 9.3e-12 44.5 8.0 4.6e-09 35.8 2.5 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EER23293.1 - 1e-05 25.0 2.4 1e-05 25.0 1.7 3.2 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EER23293.1 - 0.00094 18.8 10.9 4.7 7.6 0.3 5.4 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EER23293.1 - 0.055 13.6 9.6 1.4 9.4 0.3 4.5 4 0 0 4 4 4 0 Leucine rich repeat Mucin PF01456.12 EER23294.1 - 0.076 12.7 25.7 0.099 12.4 17.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Glycophorin_A PF01102.13 EER23294.1 - 5.6 6.7 12.5 23 4.7 8.6 1.8 1 1 0 1 1 1 0 Glycophorin A FHA PF00498.21 EER23296.1 - 1e-16 60.8 0.0 2.3e-16 59.6 0.0 1.7 1 0 0 1 1 1 1 FHA domain Y_phosphatase3 PF13350.1 EER23297.1 - 1.7e-38 132.4 0.0 3.2e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EER23297.1 - 5.1e-05 23.3 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EER23297.1 - 0.0052 16.1 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EER23297.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 EER23297.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Amino_oxidase PF01593.19 EER23298.1 - 1.3e-24 87.0 0.1 4.8e-16 58.8 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EER23298.1 - 1.1e-05 25.3 0.2 5.3e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EER23299.1 - 5e-11 42.2 1.0 7.7e-10 38.3 0.7 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EER23299.1 - 1.8e-05 23.8 0.3 6.7e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER23299.1 - 0.00011 22.1 0.0 0.00037 20.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EER23299.1 - 0.00032 19.4 1.1 0.00057 18.6 0.0 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EER23299.1 - 0.019 14.8 0.1 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase EI24 PF07264.6 EER23300.1 - 0.00013 21.4 10.0 0.00054 19.4 6.9 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-RING_2 PF13639.1 EER23301.1 - 8.6e-14 51.0 5.5 1.4e-13 50.4 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EER23301.1 - 2e-11 43.4 0.0 5.3e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EER23301.1 - 2.4e-09 37.0 5.8 3.9e-09 36.3 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EER23301.1 - 9.3e-09 35.2 1.5 1.8e-08 34.3 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EER23301.1 - 4.3e-08 32.6 3.9 6.7e-08 32.0 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER23301.1 - 8.1e-08 31.8 3.0 1.2e-07 31.2 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER23301.1 - 4.5e-07 29.4 2.6 7.1e-07 28.8 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EER23301.1 - 0.001 18.8 0.7 0.002 17.9 0.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EER23301.1 - 0.0054 16.5 3.4 0.011 15.5 2.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING RINGv PF12906.2 EER23301.1 - 0.21 11.6 4.1 0.39 10.7 2.8 1.5 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EER23301.1 - 0.24 11.3 2.4 0.55 10.2 1.7 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EER23301.1 - 0.33 10.7 3.6 0.69 9.6 2.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING-like PF08746.6 EER23301.1 - 0.48 10.4 3.2 0.89 9.5 2.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EER23301.1 - 0.83 9.2 2.5 1.4 8.5 1.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain OTT_1508_deam PF14441.1 EER23303.1 - 6.1e-32 110.3 0.0 1e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase Raptor_N PF14538.1 EER23305.1 - 7.4e-64 214.2 0.1 2.2e-63 212.7 0.0 1.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EER23305.1 - 2e-06 27.4 6.1 0.42 10.5 0.0 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 EER23305.1 - 9.5e-05 22.1 1.7 0.23 11.6 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat Atx10homo_assoc PF09759.4 EER23305.1 - 0.0039 16.9 0.2 0.0083 15.8 0.2 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Peptidase_C14 PF00656.17 EER23305.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Caspase domain DUF1546 PF07571.8 EER23305.1 - 0.069 13.2 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Kelch_5 PF13854.1 EER23306.1 - 9.2e-37 124.4 3.7 1.4e-09 37.7 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EER23306.1 - 1.1e-32 111.5 15.5 2.5e-09 36.7 0.7 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EER23306.1 - 2.8e-32 110.1 17.0 2e-07 30.9 0.1 6.1 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EER23306.1 - 3.9e-30 103.1 1.3 5.4e-12 45.0 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EER23306.1 - 3.5e-27 93.3 6.7 1.7e-10 40.6 0.5 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EER23306.1 - 3.7e-20 70.8 5.9 1.3e-07 31.1 0.1 6.6 6 0 0 6 6 6 5 Kelch motif FlxA PF14282.1 EER23306.1 - 0.0063 16.4 13.8 0.0063 16.4 9.5 5.9 4 3 2 6 6 6 1 FlxA-like protein RAG2 PF03089.9 EER23306.1 - 0.066 11.9 0.1 1 8.0 0.0 2.6 3 0 0 3 3 3 0 Recombination activating protein 2 DUF4396 PF14342.1 EER23307.1 - 1.9e-42 144.6 4.8 2.5e-42 144.2 3.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) Pkinase PF00069.20 EER23308.1 - 2.5e-38 131.7 0.0 3.1e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23308.1 - 7.7e-14 51.3 0.0 1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER23308.1 - 2.3e-05 24.2 0.0 0.0015 18.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family bZIP_1 PF00170.16 EER23309.1 - 8.9e-07 28.7 13.5 2e-06 27.6 9.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EER23309.1 - 0.0043 16.8 15.6 0.0065 16.2 10.2 1.7 1 1 0 1 1 1 1 Basic region leucine zipper Draxin PF15550.1 EER23309.1 - 0.011 15.4 2.2 0.015 15.0 1.5 1.2 1 0 0 1 1 1 0 Draxin TMF_TATA_bd PF12325.3 EER23309.1 - 0.013 15.1 5.3 0.013 15.1 3.7 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Glutaredoxin2_C PF04399.8 EER23309.1 - 0.055 13.0 0.9 0.095 12.2 0.6 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain FlaC_arch PF05377.6 EER23309.1 - 0.059 13.2 1.4 0.16 11.8 1.0 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_Maf PF03131.12 EER23309.1 - 0.068 13.4 13.2 0.14 12.4 9.1 1.5 1 1 0 1 1 1 0 bZIP Maf transcription factor Prominin PF05478.6 EER23309.1 - 0.28 8.6 2.2 0.38 8.2 1.5 1.2 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.14 EER23309.1 - 0.48 8.2 1.5 0.62 7.8 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EER23309.1 - 1.2 9.5 9.2 0.18 12.1 1.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF3431 PF11913.3 EER23310.1 - 7.9e-80 267.5 0.0 9.8e-80 267.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Phosducin PF02114.11 EER23311.1 - 4.2e-11 42.0 0.4 5.9e-11 41.5 0.3 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EER23311.1 - 0.05 13.2 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin U3_assoc_6 PF08640.6 EER23311.1 - 0.19 11.4 4.6 0.13 12.0 1.4 1.9 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Adaptin_N PF01602.15 EER23312.1 - 7.5e-110 367.7 0.0 1.1e-109 367.1 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EER23312.1 - 4.2e-60 201.9 3.5 9.7e-60 200.7 2.5 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EER23312.1 - 3.9e-15 55.9 3.1 2.3e-05 24.5 0.0 6.2 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EER23312.1 - 0.0029 17.5 9.3 1.6 8.9 0.2 6.4 8 0 0 8 8 8 2 HEAT repeat HEAT_PBS PF03130.11 EER23312.1 - 0.26 11.8 8.0 4.2 8.1 0.1 5.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EER23312.1 - 1.9 9.0 8.8 0.45 11.0 1.6 3.4 4 0 0 4 4 4 0 HEAT-like repeat F-box-like PF12937.2 EER23313.1 - 7.7e-11 41.5 0.8 2e-10 40.2 0.6 1.8 1 0 0 1 1 1 1 F-box-like Rbsn PF11464.3 EER23313.1 - 0.22 11.1 1.4 8.1 6.1 0.1 2.5 2 0 0 2 2 2 0 Rabenosyn Rab binding domain LRR_7 PF13504.1 EER23313.1 - 1.5 9.3 7.1 11 6.7 0.0 5.6 6 1 0 6 6 6 0 Leucine rich repeat Hydrolase_6 PF13344.1 EER23314.1 - 1.1e-21 76.6 0.0 2.1e-21 75.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER23314.1 - 3.3e-17 61.9 0.0 8.7e-17 60.6 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EER23314.1 - 0.00016 21.9 0.0 0.077 13.2 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EER23314.1 - 0.0031 17.9 0.0 0.12 12.7 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Apt1 PF10351.4 EER23314.1 - 0.016 14.0 0.2 0.058 12.2 0.0 1.7 2 0 0 2 2 2 0 Golgi-body localisation protein domain Aldo_ket_red PF00248.16 EER23315.1 - 1.1e-54 185.1 0.0 1.3e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TnpV PF14198.1 EER23315.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Hydrolase_6 PF13344.1 EER23316.1 - 4.3e-24 84.3 0.0 1.1e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER23316.1 - 1.9e-16 59.5 0.0 6.1e-16 57.8 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EER23316.1 - 0.0052 17.0 0.0 4.3 7.5 0.0 3.0 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EER23316.1 - 0.023 15.1 0.0 8.9 6.6 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.15 EER23317.1 - 7.3e-68 228.7 0.5 1.2e-66 224.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EER23317.1 - 6.8e-10 38.6 0.1 1.3e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF1570 PF07607.6 EER23317.1 - 0.053 13.5 0.2 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) tRNA-synt_2d PF01409.15 EER23317.1 - 0.053 12.7 0.2 2.9 6.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.1 EER23317.1 - 0.066 13.0 0.1 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain SIP1 PF04938.7 EER23318.1 - 1.4e-06 27.8 0.0 0.00025 20.5 0.0 2.6 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) PX PF00787.19 EER23319.1 - 1e-16 60.7 0.0 1.1e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 PX domain SNARE PF05739.14 EER23319.1 - 2.5e-08 33.4 3.9 8.2e-08 31.8 2.7 2.0 1 0 0 1 1 1 1 SNARE domain Ku PF02735.11 EER23320.1 - 2.3e-24 85.9 0.0 3.9e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EER23320.1 - 4.5e-17 62.0 0.0 1.2e-16 60.6 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 EER23320.1 - 4.1e-08 32.9 0.0 5.6e-06 25.9 0.0 2.8 1 1 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 EER23320.1 - 0.00079 19.5 0.0 0.0016 18.5 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EER23320.1 - 0.0023 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4149 PF13664.1 EER23321.1 - 7.4e-26 90.1 2.3 8.1e-26 90.0 0.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) AAA_13 PF13166.1 EER23322.1 - 0.0031 16.0 4.9 0.026 12.9 3.4 1.9 1 1 0 1 1 1 1 AAA domain LemA PF04011.7 EER23322.1 - 0.0034 16.5 1.5 0.022 13.8 0.1 2.5 2 1 1 3 3 3 1 LemA family GAS PF13851.1 EER23322.1 - 0.0051 16.0 0.5 0.0051 16.0 0.4 3.0 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EER23322.1 - 0.0063 16.3 9.6 2.6 7.8 0.2 3.6 2 1 0 3 3 3 2 Protein of unknown function (DUF1664) DUF677 PF05055.7 EER23322.1 - 0.013 14.1 2.8 0.11 11.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF677) DASH_Spc34 PF08657.5 EER23322.1 - 0.018 14.6 8.8 0.46 10.1 1.4 3.4 1 1 2 3 3 3 0 DASH complex subunit Spc34 Resolvase PF00239.16 EER23322.1 - 0.038 13.8 4.5 1.1 9.0 0.3 2.5 2 0 0 2 2 2 0 Resolvase, N terminal domain A1_Propeptide PF07966.7 EER23322.1 - 0.11 12.3 0.3 0.68 9.8 0.0 2.4 2 0 0 2 2 2 0 A1 Propeptide Laminin_II PF06009.7 EER23322.1 - 0.16 11.7 9.1 0.14 11.8 0.7 3.0 2 1 0 2 2 2 0 Laminin Domain II Apolipoprotein PF01442.13 EER23322.1 - 0.29 10.6 17.3 27 4.2 11.8 2.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain IncA PF04156.9 EER23322.1 - 0.32 10.5 12.8 7.8 6.0 0.0 3.6 3 1 0 3 3 3 0 IncA protein DUF3552 PF12072.3 EER23322.1 - 0.32 10.1 9.3 2.6 7.2 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Baculo_PEP_C PF04513.7 EER23322.1 - 0.53 10.1 5.3 26 4.6 0.1 3.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_I PF06008.9 EER23322.1 - 1.1 8.5 11.9 0.068 12.4 3.1 2.3 1 1 0 2 2 2 0 Laminin Domain I Tropomyosin_1 PF12718.2 EER23322.1 - 1.2 9.0 8.3 0.17 11.7 1.9 2.2 2 0 0 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.4 EER23322.1 - 1.2 9.3 10.7 1.1 9.4 0.3 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliJ PF02050.11 EER23322.1 - 1.4 8.9 6.7 8.8 6.4 0.4 3.1 2 1 1 3 3 3 0 Flagellar FliJ protein Spc7 PF08317.6 EER23322.1 - 1.8 7.1 12.2 0.028 13.0 1.5 2.5 2 1 1 3 3 3 0 Spc7 kinetochore protein DUF2730 PF10805.3 EER23322.1 - 3 7.6 11.2 8.9 6.1 0.5 4.7 2 2 3 5 5 5 0 Protein of unknown function (DUF2730) Transposase_22 PF02994.9 EER23322.1 - 3.3 6.1 10.3 0.68 8.3 1.4 2.2 1 1 1 2 2 2 0 L1 transposable element DUF812 PF05667.6 EER23322.1 - 3.5 6.0 12.2 0.23 9.9 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) TBPIP PF07106.8 EER23322.1 - 3.9 6.9 12.1 0.37 10.3 0.8 2.9 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GP41 PF00517.12 EER23322.1 - 4.1 6.9 9.4 0.85 9.1 0.1 3.1 3 0 0 3 3 3 0 Retroviral envelope protein DUF745 PF05335.8 EER23322.1 - 4.1 6.8 10.7 5 6.6 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF745) APG6 PF04111.7 EER23322.1 - 4.5 6.2 8.2 0.36 9.8 1.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF724 PF05266.9 EER23322.1 - 9.6 5.7 10.7 2.4 7.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Sugar_tr PF00083.19 EER23323.1 - 6.3e-84 282.1 22.2 7.3e-84 281.9 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER23323.1 - 5.7e-15 54.8 30.9 5.7e-15 54.8 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Reo_sigmaC PF04582.7 EER23324.1 - 0.0034 16.6 10.6 0.12 11.5 0.8 3.2 3 0 0 3 3 3 2 Reovirus sigma C capsid protein CorA PF01544.13 EER23324.1 - 0.0055 15.7 2.7 1.2 8.1 0.0 3.2 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein DUF948 PF06103.6 EER23324.1 - 0.021 14.6 3.0 19 5.1 0.0 4.4 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) CHASE3 PF05227.8 EER23324.1 - 0.027 14.1 0.1 0.027 14.1 0.1 3.8 4 2 0 4 4 4 0 CHASE3 domain LPP PF04728.8 EER23324.1 - 0.061 13.1 7.0 1.3 8.9 0.2 4.2 4 0 0 4 4 4 0 Lipoprotein leucine-zipper NPV_P10 PF05531.7 EER23324.1 - 0.42 10.8 17.4 4.4 7.6 0.4 5.4 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Syntaxin_2 PF14523.1 EER23324.1 - 0.82 9.7 16.6 7 6.7 0.1 5.0 4 1 0 4 4 4 0 Syntaxin-like protein TMF_TATA_bd PF12325.3 EER23324.1 - 0.89 9.2 7.7 3.9 7.2 0.1 4.2 4 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 EER23324.1 - 1 9.4 10.0 4.5 7.3 0.0 4.9 3 1 1 5 5 5 0 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 EER23324.1 - 1 8.8 14.3 2.6 7.5 1.1 4.8 2 2 2 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4404 PF14357.1 EER23324.1 - 4.1 7.8 11.5 1.5 9.3 0.2 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) Topoisom_bac PF01131.15 EER23325.1 - 2.6e-83 280.1 0.0 3.4e-83 279.7 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EER23325.1 - 2.8e-19 68.9 0.0 1.2e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Toprim domain DUF1295 PF06966.7 EER23326.1 - 6.1e-37 127.1 14.0 1.4e-36 125.9 9.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2373 PF10180.4 EER23326.1 - 0.022 14.2 0.8 0.055 13.0 0.5 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) ICMT PF04140.9 EER23326.1 - 0.68 10.1 0.0 0.68 10.1 0.0 3.0 3 1 1 4 4 4 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Peptidase_M41 PF01434.13 EER23327.1 - 5.9e-75 251.3 0.0 1.2e-74 250.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EER23327.1 - 1.2e-42 145.1 0.0 3.8e-42 143.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EER23327.1 - 3.9e-09 36.6 0.7 9.2e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 EER23327.1 - 0.00031 20.4 0.0 0.0011 18.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EER23327.1 - 0.00097 19.2 0.1 0.22 11.6 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EER23327.1 - 0.0018 19.0 0.0 0.011 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EER23327.1 - 0.0058 16.3 0.5 0.02 14.6 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EER23327.1 - 0.007 15.4 0.0 0.018 14.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EER23327.1 - 0.0085 14.8 0.1 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EER23327.1 - 0.0092 15.9 0.2 0.15 12.0 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EER23327.1 - 0.018 14.4 0.0 0.057 12.8 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EER23327.1 - 0.021 14.2 1.8 0.19 11.0 0.2 2.8 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 EER23327.1 - 0.062 13.6 1.6 0.81 10.0 0.0 3.2 2 1 0 3 3 3 0 AAA domain ParD PF09386.5 EER23327.1 - 0.072 13.2 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 Antitoxin ParD AAA_14 PF13173.1 EER23327.1 - 0.086 12.7 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EER23327.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sperm_Ag_HE2 PF05324.8 EER23327.1 - 0.17 11.8 0.8 1.2 9.1 0.1 2.8 3 0 0 3 3 3 0 Sperm antigen HE2 Fungal_trans PF04082.13 EER23328.1 - 1.1e-31 109.6 0.0 2.5e-31 108.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER23328.1 - 4e-10 39.4 13.2 6.8e-10 38.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA-synt_2b PF00587.20 EER23329.1 - 1.4e-43 148.5 0.2 2.2e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EER23329.1 - 8.2e-16 57.7 0.1 1.6e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EER23329.1 - 2.1e-13 49.9 0.0 3.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EER23329.1 - 0.00027 20.6 0.0 0.00055 19.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 EER23330.1 - 6.8e-43 145.7 2.4 8.7e-43 145.4 0.0 1.9 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 EER23331.1 - 4.1e-13 49.4 2.6 8.2e-13 48.5 1.8 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4345 PF14248.1 EER23331.1 - 0.59 9.5 5.0 0.39 10.1 1.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4345) WSC PF01822.14 EER23332.1 - 2.1e-16 59.5 11.0 4.1e-16 58.6 7.6 1.5 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EER23332.1 - 2.4e-07 29.9 2.0 2.4e-07 29.9 1.4 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CD99L2 PF12301.3 EER23332.1 - 0.0062 16.2 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 CD99 antigen like protein 2 Podoplanin PF05808.6 EER23332.1 - 0.011 15.2 0.4 0.019 14.5 0.3 1.4 1 0 0 1 1 1 0 Podoplanin OppC_N PF12911.2 EER23332.1 - 0.024 13.9 0.0 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4366 PF14283.1 EER23332.1 - 0.027 13.9 2.7 0.099 12.0 1.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF1191 PF06697.7 EER23332.1 - 0.086 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF4448 PF14610.1 EER23332.1 - 0.089 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) APH PF01636.18 EER23334.1 - 0.0014 18.3 0.5 0.013 15.2 0.3 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EER23335.1 - 1.4e-06 27.6 0.0 1.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EER23335.1 - 0.0012 17.9 0.1 0.0021 17.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER23335.1 - 0.024 14.3 0.1 0.041 13.6 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Rb_C PF08934.5 EER23337.1 - 0.67 9.5 6.3 0.092 12.3 1.2 1.8 2 0 0 2 2 2 0 Rb C-terminal domain DUF2370 PF10176.4 EER23338.1 - 7.3e-87 290.5 0.0 1e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) DUF202 PF02656.10 EER23338.1 - 0.062 13.5 0.1 0.23 11.6 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Calpain_inhib PF00748.14 EER23338.1 - 0.3 11.4 3.5 1.5 9.1 0.5 2.2 2 0 0 2 2 2 0 Calpain inhibitor MCPVI PF02993.9 EER23339.1 - 0.021 14.9 0.1 0.023 14.8 0.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI CoA_trans PF01144.18 EER23340.1 - 2.4e-105 350.5 0.5 3.1e-63 212.8 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase RPT PF13446.1 EER23341.1 - 2.4e-53 177.4 6.1 2.4e-22 78.0 0.1 4.5 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.24 EER23341.1 - 6e-50 169.8 0.0 1.4e-49 168.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER23341.1 - 1.6e-10 40.9 0.3 3.3e-07 30.0 0.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 EER23341.1 - 0.011 15.4 0.0 0.049 13.3 0.0 2.0 2 0 0 2 2 2 0 PUB domain DUF465 PF04325.8 EER23341.1 - 1 9.0 6.2 0.69 9.6 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Tim17 PF02466.14 EER23342.1 - 4.4e-15 55.8 6.5 6e-15 55.4 4.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EER23342.1 - 1.5 8.9 5.9 1.1 9.4 2.8 1.8 1 1 1 2 2 2 0 Bacteriocin class II with double-glycine leader peptide PH PF00169.24 EER23343.1 - 2.2e-09 37.4 0.1 8.2e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 PH domain P4Ha_N PF08336.6 EER23343.1 - 0.091 12.5 0.2 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Prominin PF05478.6 EER23343.1 - 0.13 9.7 0.1 0.18 9.2 0.1 1.1 1 0 0 1 1 1 0 Prominin RRM_1 PF00076.17 EER23344.1 - 1.8e-48 162.0 0.0 5.4e-18 64.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER23344.1 - 2.5e-39 133.0 0.0 1.5e-14 53.7 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER23344.1 - 1.5e-24 85.5 0.0 4.3e-08 32.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EER23344.1 - 0.0015 18.3 0.1 1.4 8.7 0.0 3.6 4 0 0 4 4 4 1 RNA binding motif SPOR PF05036.8 EER23344.1 - 0.013 15.5 0.0 4.7 7.4 0.0 3.4 3 0 0 3 3 3 0 Sporulation related domain Limkain-b1 PF11608.3 EER23344.1 - 0.019 14.6 0.2 18 5.1 0.0 3.7 3 2 0 3 3 3 0 Limkain b1 ATP-grasp_2 PF08442.5 EER23344.1 - 0.03 13.6 0.0 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain HTH_Tnp_1 PF01527.15 EER23344.1 - 0.12 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Transposase YoaP PF14268.1 EER23344.1 - 1.4 8.2 3.4 1.9 7.7 0.0 2.8 4 0 0 4 4 4 0 YoaP-like FmdA_AmdA PF03069.10 EER23345.1 - 5.4e-58 196.4 0.0 2.4e-30 105.4 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family CBM_19 PF03427.8 EER23345.1 - 0.039 13.7 0.1 0.089 12.5 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) DUF1554 PF07588.6 EER23345.1 - 0.059 12.8 0.2 0.16 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1554) DUF2457 PF10446.4 EER23346.1 - 0.0029 16.3 3.6 0.0029 16.3 2.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2457) BSP_II PF05432.6 EER23346.1 - 0.012 14.8 0.3 0.021 14.1 0.1 1.4 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) Herpes_gE PF02480.11 EER23346.1 - 0.019 13.2 3.4 0.41 8.8 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E RXT2_N PF08595.6 EER23346.1 - 0.034 13.9 1.3 0.047 13.4 0.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal CDC45 PF02724.9 EER23346.1 - 0.041 11.9 0.5 0.045 11.7 0.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Tom22 PF04281.8 EER23346.1 - 0.062 12.8 2.7 0.11 12.0 1.8 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Ebola_NP PF05505.7 EER23346.1 - 0.35 8.8 4.0 0.45 8.5 2.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein GCIP PF13324.1 EER23346.1 - 0.47 9.6 3.0 24 4.0 4.0 1.9 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting Sigma70_ner PF04546.8 EER23346.1 - 0.99 8.9 4.5 1.4 8.4 3.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 EER23346.1 - 1.2 6.9 7.4 1.5 6.6 5.1 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EER23346.1 - 2.9 7.5 9.6 4.2 7.0 6.6 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SDA1 PF05285.7 EER23346.1 - 4.7 6.3 7.9 6.3 5.9 5.5 1.1 1 0 0 1 1 1 0 SDA1 TPR_11 PF13414.1 EER23347.1 - 1.1e-09 37.7 10.5 3e-07 29.9 0.1 4.9 5 1 1 6 6 6 2 TPR repeat TPR_2 PF07719.12 EER23347.1 - 6.4e-07 28.8 19.0 5.8e-05 22.6 0.0 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER23347.1 - 4.6e-06 27.1 31.3 0.0009 19.8 0.1 7.2 7 2 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EER23347.1 - 0.0004 19.8 10.6 0.0016 17.9 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EER23347.1 - 0.0012 19.2 19.2 0.64 10.8 0.1 7.2 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER23347.1 - 0.0022 17.6 0.7 1.8 8.5 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER23347.1 - 0.0036 17.5 12.6 0.65 10.3 0.2 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EER23347.1 - 0.048 13.6 14.4 1.2 9.0 1.8 4.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EER23347.1 - 0.057 13.2 0.2 6.4 6.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EER23347.1 - 0.069 13.0 3.0 1.4 8.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.1 EER23348.1 - 2.3e-10 40.8 0.1 3.7e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EER23348.1 - 0.00019 21.0 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 EER23348.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein AA_permease_2 PF13520.1 EER23349.1 - 5e-50 170.2 35.7 6.2e-50 169.9 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease APH PF01636.18 EER23352.1 - 1.2e-14 54.6 0.0 4.8e-14 52.6 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EER23352.1 - 0.00029 19.6 0.0 0.14 10.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.15 EER23352.1 - 0.037 13.1 0.0 0.077 12.1 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3435 PF11917.3 EER23353.1 - 1.9e-77 260.7 0.0 2.2e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) COQ9 PF08511.6 EER23354.1 - 1.6e-23 81.9 0.1 2.7e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 COQ9 WD40 PF00400.27 EER23356.1 - 9.5e-17 60.1 0.2 8.6e-05 22.2 0.1 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DNA_methylase PF00145.12 EER23357.1 - 3.5e-35 121.6 0.0 6.2e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EER23357.1 - 6.8e-06 25.8 0.9 0.13 12.0 0.3 3.0 2 1 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 EER23357.1 - 1.3e-05 24.9 0.0 3.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain DUF3104 PF11302.3 EER23357.1 - 0.14 11.5 0.2 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3104) RasGAP PF00616.14 EER23358.1 - 9.7e-47 159.1 0.0 1.2e-45 155.6 0.0 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EER23358.1 - 6.6e-06 25.8 0.1 1.7e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 C2 domain APG9 PF04109.11 EER23359.1 - 9.8e-170 564.3 2.2 1.3e-169 563.9 1.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Oxidored_FMN PF00724.15 EER23360.1 - 1.3e-68 231.5 0.0 1.1e-67 228.4 0.0 1.9 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_47 PF01532.15 EER23361.1 - 1.2e-180 601.0 0.0 1.4e-180 600.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2013 PF09431.5 EER23362.1 - 2.5e-52 176.3 4.5 2.7e-52 176.2 0.9 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) Glyco_hydro_17 PF00332.13 EER23363.1 - 4e-06 26.0 3.6 1.3e-05 24.4 0.3 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Peptidase_M24 PF00557.19 EER23364.1 - 3.1e-09 36.7 0.1 4.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Aminotran_1_2 PF00155.16 EER23365.1 - 2.1e-35 122.3 0.0 2.5e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EER23365.1 - 0.0059 14.9 0.0 0.009 14.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glucan_synthase PF02364.10 EER23366.1 - 0 1480.8 0.0 0 1480.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EER23366.1 - 1.8e-40 137.5 0.3 4.2e-40 136.3 0.2 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Peptidase_C70 PF12385.3 EER23366.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Papain-like cysteine protease AvrRpt2 Glyco_hydro_72 PF03198.9 EER23367.1 - 4.4e-134 446.3 7.8 5.5e-134 446.0 5.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EER23367.1 - 5.6e-27 94.0 2.4 1.5e-26 92.6 1.7 1.8 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EER23367.1 - 3.9e-05 22.9 0.3 0.00089 18.5 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_S8 PF00082.17 EER23368.1 - 4.2e-47 160.6 10.5 4.2e-47 160.6 7.2 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EER23368.1 - 2.4e-09 37.6 0.0 5e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 HSP20 PF00011.16 EER23369.1 - 1.3e-18 66.6 0.0 5.4e-18 64.7 0.0 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family SprT-like PF10263.4 EER23370.1 - 1.1e-54 184.3 3.1 1.6e-54 183.7 2.2 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EER23370.1 - 0.023 14.7 0.1 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily DUF4379 PF14311.1 EER23370.1 - 0.1 12.4 4.2 0.36 10.6 2.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Mog1 PF04603.7 EER23371.1 - 7.1e-17 61.6 0.1 6.6e-15 55.2 0.0 2.2 1 1 0 1 1 1 1 Ran-interacting Mog1 protein NYN PF01936.13 EER23372.1 - 2.3e-05 24.7 0.0 0.00084 19.6 0.0 2.5 1 1 0 1 1 1 1 NYN domain HSP9_HSP12 PF04119.7 EER23373.1 - 1.5e-28 98.6 6.0 1.5e-28 98.6 4.2 1.5 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.2 EER23373.1 - 0.0052 17.1 1.4 0.0089 16.3 1.0 1.5 1 0 0 1 1 1 1 YtxH-like protein Tombus_movement PF05318.7 EER23373.1 - 0.3 11.7 4.3 0.33 11.6 2.6 1.4 1 1 0 1 1 1 0 Tombusvirus movement protein Cauli_AT PF03233.8 EER23374.1 - 0.028 14.1 0.7 0.028 14.1 0.5 2.3 2 1 0 2 2 2 0 Aphid transmission protein IncA PF04156.9 EER23374.1 - 0.046 13.3 21.3 4.7 6.7 13.2 2.8 1 1 1 2 2 2 0 IncA protein HR1 PF02185.11 EER23374.1 - 0.081 12.6 0.6 0.081 12.6 0.4 3.0 3 0 0 3 3 3 0 Hr1 repeat Syntaxin PF00804.20 EER23374.1 - 0.19 11.9 7.9 0.27 11.3 0.2 2.8 2 1 1 3 3 3 0 Syntaxin Syntaxin-6_N PF09177.6 EER23374.1 - 0.67 10.4 7.1 4.1 7.8 0.3 3.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF342 PF03961.8 EER23374.1 - 5.1 5.3 8.0 18 3.5 4.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Asp-B-Hydro_N PF05279.6 EER23374.1 - 5.3 6.8 9.8 1.8 8.3 3.8 1.9 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region COG6 PF06419.6 EER23375.1 - 3.2e-236 785.3 0.1 3.5e-236 785.1 0.1 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 HAUS5 PF14817.1 EER23375.1 - 0.012 14.2 0.1 0.021 13.3 0.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 COG2 PF06148.6 EER23375.1 - 0.013 15.3 1.3 0.09 12.6 0.2 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 RmuC PF02646.11 EER23375.1 - 0.019 13.8 0.5 0.36 9.6 0.5 2.3 2 0 0 2 2 2 0 RmuC family Laminin_II PF06009.7 EER23375.1 - 0.026 14.2 0.2 0.097 12.4 0.1 2.1 1 0 0 1 1 1 0 Laminin Domain II Transcrip_act PF04949.8 EER23375.1 - 0.087 12.4 0.1 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 Transcriptional activator NIF3 PF01784.13 EER23376.1 - 2.6e-55 187.6 0.0 3.4e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) BolA PF01722.13 EER23377.1 - 1.9e-21 75.8 0.0 2.3e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein QLQ PF08880.6 EER23377.1 - 0.0095 15.3 0.5 0.017 14.5 0.3 1.4 1 0 0 1 1 1 1 QLQ MFS_1 PF07690.11 EER23378.1 - 4.1e-38 130.9 62.9 2.4e-37 128.4 44.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER23378.1 - 1.9e-13 49.5 24.6 2.8e-13 48.9 17.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER23378.1 - 5.6e-13 48.2 19.0 5.6e-13 48.2 13.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter Chal_sti_synt_N PF00195.14 EER23379.1 - 9.1e-20 70.8 0.0 1.4e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EER23379.1 - 3.7e-16 59.4 0.0 1.1e-15 57.8 0.0 1.8 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 EER23379.1 - 0.0001 21.4 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EER23379.1 - 0.0011 18.9 0.0 0.0055 16.6 0.0 2.1 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Aconitase PF00330.15 EER23379.1 - 0.14 10.5 0.0 0.24 9.8 0.0 1.3 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) HSF_DNA-bind PF00447.12 EER23380.1 - 2.8e-38 130.2 1.5 2.3e-37 127.3 0.1 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 EER23380.1 - 2.1e-21 76.0 0.0 4e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DUF3540 PF12059.3 EER23380.1 - 0.047 13.3 1.2 0.076 12.6 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3540) W2 PF02020.13 EER23381.1 - 2.9e-16 59.1 5.1 2.9e-16 59.1 3.5 2.8 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EER23381.1 - 2.5e-10 39.3 14.8 0.00028 20.2 2.8 4.0 1 1 4 5 5 5 5 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EER23381.1 - 8.5e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EER23381.1 - 0.002 17.6 17.3 0.16 11.5 1.7 3.5 1 1 2 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EER23381.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain IBR PF01485.16 EER23382.1 - 2.8e-20 71.9 50.3 1.4e-10 40.8 3.9 4.8 4 1 1 5 5 5 3 IBR domain zf-C3HC4_2 PF13923.1 EER23382.1 - 3.1e-05 23.9 8.2 3.1e-05 23.9 5.7 4.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER23382.1 - 0.00012 21.6 6.1 0.00012 21.6 4.2 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER23382.1 - 0.00019 21.2 47.0 0.00092 18.9 5.9 3.6 2 1 1 3 3 3 2 Ring finger domain zf-RING_5 PF14634.1 EER23382.1 - 0.0027 17.3 9.6 0.0027 17.3 6.7 3.6 3 0 0 3 3 3 2 zinc-RING finger domain UN_NPL4 PF11543.3 EER23382.1 - 0.032 14.5 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mito_carr PF00153.22 EER23383.1 - 3.8e-70 231.6 5.8 8.6e-25 86.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein AAA PF00004.24 EER23384.1 - 1.4e-37 128.8 0.1 3.5e-37 127.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EER23384.1 - 2.9e-07 30.2 0.0 0.00013 21.7 0.0 3.2 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EER23384.1 - 2.4e-06 27.7 0.2 4.2e-05 23.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EER23384.1 - 4.8e-05 22.5 0.0 9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EER23384.1 - 0.00025 20.7 0.0 0.0007 19.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EER23384.1 - 0.00091 19.2 0.9 0.0099 15.8 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EER23384.1 - 0.0011 18.3 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EER23384.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EER23384.1 - 0.0033 16.6 0.1 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EER23384.1 - 0.0037 17.1 0.0 0.011 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EER23384.1 - 0.0038 16.6 0.4 0.22 10.9 0.1 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 EER23384.1 - 0.0039 15.9 0.0 0.0065 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EER23384.1 - 0.008 15.9 0.1 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EER23384.1 - 0.01 14.7 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 EER23384.1 - 0.016 16.0 0.0 0.058 14.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EER23384.1 - 0.017 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EER23384.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EER23384.1 - 0.053 13.2 0.0 0.85 9.2 0.0 2.4 1 1 0 1 1 1 0 Archaeal ATPase AAA_28 PF13521.1 EER23384.1 - 0.069 13.1 1.5 0.12 12.3 0.0 2.1 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 EER23384.1 - 0.074 12.7 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.16 EER23384.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase PhoH PF02562.11 EER23384.1 - 0.15 11.2 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 EER23384.1 - 0.17 10.7 0.2 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain GlyL_C PF12524.3 EER23385.1 - 0.05 13.5 1.1 0.14 12.1 0.8 1.7 1 0 0 1 1 1 0 dsDNA virus glycoprotein L C terminal Glyco_transf_20 PF00982.16 EER23386.1 - 1.1e-200 667.1 0.0 1.2e-200 667.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EER23386.1 - 0.018 14.5 0.1 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 Starch synthase catalytic domain Lactamase_B PF00753.22 EER23387.1 - 6e-23 81.5 1.2 8.3e-23 81.0 0.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EER23387.1 - 0.00032 20.2 0.2 0.00068 19.2 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EER23387.1 - 0.00086 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Aconitase PF00330.15 EER23388.1 - 2e-176 587.0 0.0 4.5e-176 585.9 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EER23388.1 - 1.2e-46 158.0 0.0 2.2e-46 157.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Zn_clus PF00172.13 EER23389.1 - 0.31 11.0 12.2 0.13 12.2 1.4 2.8 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CD20 PF04103.10 EER23390.1 - 0.0057 16.5 11.2 0.22 11.4 1.4 2.3 1 1 1 2 2 2 2 CD20-like family Claudin_2 PF13903.1 EER23390.1 - 6.2 6.4 12.3 1.6 8.3 4.1 2.6 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction zf-C2H2_jaz PF12171.3 EER23391.1 - 2.3e-10 40.2 3.3 3.9e-10 39.5 2.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding Ribosomal_L2 PF00181.18 EER23391.1 - 0.002 18.0 1.9 0.025 14.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain zf-C2H2_6 PF13912.1 EER23391.1 - 0.0029 17.4 0.6 0.0047 16.7 0.4 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.2 EER23391.1 - 0.0039 17.3 1.8 0.0065 16.6 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EER23391.1 - 0.0086 16.1 1.3 0.039 14.0 0.4 1.9 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EER23391.1 - 0.023 15.0 0.7 0.052 13.9 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-U1 PF06220.7 EER23391.1 - 0.029 13.9 0.8 0.069 12.7 0.5 1.6 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.21 EER23391.1 - 0.055 13.8 0.6 0.1 12.9 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Mito_carr PF00153.22 EER23392.1 - 3.5e-50 167.6 0.7 2.6e-20 71.9 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Phage_holin_3 PF05106.7 EER23392.1 - 0.029 14.3 0.2 6.4 6.8 0.0 2.9 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) SNF2_N PF00176.18 EER23393.1 - 2.1e-66 223.7 0.0 2.9e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EER23393.1 - 5.1e-59 199.3 4.0 1.9e-58 197.5 2.2 2.1 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EER23393.1 - 1.1e-13 50.8 0.0 4e-13 49.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EER23393.1 - 3.8e-05 22.6 0.0 0.00029 19.7 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EER23393.1 - 0.029 14.2 0.0 0.084 12.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Vac14_Fig4_bd PF11916.3 EER23394.1 - 3.4e-83 277.2 8.6 3.4e-83 277.2 6.0 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EER23394.1 - 4.4e-44 148.8 0.0 1.3e-41 140.8 0.0 3.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EER23394.1 - 2.6e-06 27.6 1.9 0.025 14.8 0.0 4.8 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EER23394.1 - 1.5e-05 25.3 4.8 0.022 15.2 0.0 5.7 4 1 1 5 5 5 1 HEAT-like repeat HEAT PF02985.17 EER23394.1 - 0.00012 21.8 5.1 4 7.7 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat Arm PF00514.18 EER23394.1 - 0.024 14.4 0.1 9.6 6.2 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Gly-zipper_OmpA PF13436.1 EER23394.1 - 1.3 8.6 6.8 4.5 6.9 2.5 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ABC_membrane PF00664.18 EER23395.1 - 1.1e-37 129.9 10.3 1.5e-37 129.4 7.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EER23395.1 - 3.4e-35 121.3 0.0 6.9e-35 120.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EER23395.1 - 1.7e-07 31.5 0.2 0.0021 18.0 0.0 2.5 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EER23395.1 - 1.5e-05 24.3 0.0 0.0087 15.3 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EER23395.1 - 0.00012 22.1 0.1 0.00063 19.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EER23395.1 - 0.0009 20.0 0.1 0.0027 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EER23395.1 - 0.0013 18.8 0.0 0.0066 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EER23395.1 - 0.0022 17.5 0.0 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EER23395.1 - 0.0042 16.5 0.0 0.01 15.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 EER23395.1 - 0.0056 16.5 0.0 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EER23395.1 - 0.0058 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EER23395.1 - 0.0065 16.7 0.1 0.082 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EER23395.1 - 0.03 13.7 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EER23395.1 - 0.037 13.9 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EER23395.1 - 0.04 14.1 0.0 0.3 11.2 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EER23395.1 - 0.044 14.1 1.9 0.064 13.5 0.0 2.1 3 0 0 3 3 2 0 AAA domain ABC_ATPase PF09818.4 EER23395.1 - 0.051 12.1 0.0 0.54 8.7 0.0 2.0 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.20 EER23395.1 - 0.084 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 EER23395.1 - 0.13 10.9 0.0 0.2 10.2 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AIM24 PF01987.12 EER23396.1 - 1.9e-42 145.1 0.0 2.4e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 PriCT_1 PF08708.6 EER23396.1 - 0.0088 15.8 0.1 0.029 14.1 0.1 1.8 2 0 0 2 2 2 1 Primase C terminal 1 (PriCT-1) PCI PF01399.22 EER23397.1 - 5.9e-11 42.6 0.0 1.1e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 PCI domain NAD_binding_10 PF13460.1 EER23398.1 - 8.8e-19 68.2 0.0 1.3e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EER23398.1 - 6.5e-14 51.9 0.0 1.4e-13 50.7 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EER23398.1 - 3.5e-12 46.1 0.0 4.4e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EER23398.1 - 3.5e-11 42.3 0.0 5.7e-11 41.6 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EER23398.1 - 3.9e-08 32.5 0.0 1.2e-06 27.6 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EER23398.1 - 7.2e-06 25.0 0.2 0.00048 19.1 0.2 2.9 1 1 0 1 1 1 1 Male sterility protein HIM1 PF08732.5 EER23398.1 - 0.00098 17.6 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 HIM1 Saccharop_dh PF03435.13 EER23398.1 - 0.0025 16.8 0.0 0.0035 16.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EER23398.1 - 0.0028 17.6 0.0 0.0057 16.5 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase DDE_Tnp_1_3 PF13612.1 EER23398.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain KR PF08659.5 EER23398.1 - 0.082 12.5 0.0 0.78 9.3 0.0 2.2 1 1 0 1 1 1 0 KR domain NAD_binding_2 PF03446.10 EER23398.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HEM4 PF02602.10 EER23399.1 - 6.4e-33 113.9 0.0 1.3e-32 112.9 0.0 1.5 1 1 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Pkinase PF00069.20 EER23400.1 - 9.4e-74 247.8 0.0 1.1e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23400.1 - 5.1e-32 110.9 0.0 6.6e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER23400.1 - 0.00055 18.9 0.0 0.0015 17.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EER23400.1 - 0.0022 17.0 0.1 0.0036 16.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER23400.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EER23400.1 - 0.051 12.4 0.1 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Sec23_trunk PF04811.10 EER23401.1 - 1.4e-70 237.4 0.0 2.7e-70 236.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EER23401.1 - 1.8e-23 81.9 0.1 1.8e-22 78.7 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EER23401.1 - 9.5e-18 63.4 5.1 1.7e-17 62.6 3.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EER23401.1 - 2.6e-17 63.0 0.1 6e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EER23401.1 - 2.9e-07 30.0 0.0 6e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Kinesin PF00225.18 EER23402.1 - 9.2e-82 274.4 0.1 1.7e-81 273.5 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 EER23402.1 - 0.0097 15.5 0.1 0.061 13.0 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EER23402.1 - 0.016 15.3 1.7 0.02 15.0 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_3 PF12836.2 EER23402.1 - 0.1 12.5 1.2 12 5.9 0.1 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif RTA1 PF04479.8 EER23403.1 - 5.3e-12 45.7 3.9 1.7e-11 44.0 2.7 1.7 1 1 0 1 1 1 1 RTA1 like protein Gaa1 PF04114.9 EER23405.1 - 2.7e-97 326.5 5.2 4.5e-97 325.8 3.6 1.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Ytp1 PF10355.4 EER23406.1 - 4.5e-113 376.9 11.3 4.5e-113 376.9 7.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EER23406.1 - 3.5e-30 103.6 8.4 3.5e-30 103.6 5.8 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) UCH PF00443.24 EER23407.1 - 1.7e-60 204.4 0.7 2.2e-60 204.0 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER23407.1 - 3.1e-31 108.8 0.2 4.2e-31 108.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EER23407.1 - 2.2e-06 27.6 2.7 3.9e-06 26.8 0.2 2.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-ribbon_3 PF13248.1 EER23407.1 - 0.047 12.9 3.5 0.68 9.2 0.1 2.9 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EER23407.1 - 0.1 12.2 2.6 0.77 9.4 0.1 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DUF377 PF04041.8 EER23407.1 - 0.17 10.6 0.0 0.33 9.6 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF377) DASH_Dam1 PF08653.5 EER23408.1 - 1.9e-29 101.2 1.6 2.5e-29 100.8 1.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 CRAL_TRIO PF00650.15 EER23409.1 - 7e-42 142.6 0.0 2.5e-41 140.8 0.0 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EER23409.1 - 8.3e-15 54.6 0.1 2.1e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EER23409.1 - 7.6e-11 42.1 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HIT PF01230.18 EER23410.1 - 3.6e-17 62.6 0.0 5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EER23410.1 - 5.2e-10 39.5 0.0 6.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EER23410.1 - 0.062 12.9 0.0 0.08 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Peptidase_M20 PF01546.23 EER23411.1 - 1.2e-20 73.8 0.0 2e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EER23411.1 - 0.00013 21.6 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EER23411.1 - 0.0027 17.4 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 S10_plectin PF03501.10 EER23412.1 - 4.4e-42 141.8 0.2 5.3e-42 141.6 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 EER23413.1 - 9.8e-63 210.6 0.3 1.6e-62 209.9 0.2 1.3 1 0 0 1 1 1 1 Telomere stability and silencing MMR_HSR1 PF01926.18 EER23414.1 - 3.6e-07 30.1 0.0 8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EER23414.1 - 0.11 11.6 0.0 0.4 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 tRNA-synt_1 PF00133.17 EER23415.1 - 6.4e-38 130.1 0.0 2.1e-27 95.4 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EER23415.1 - 3.4e-20 72.0 0.0 1.2e-12 47.2 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EER23415.1 - 9.7e-13 48.1 0.2 2.5e-12 46.7 0.2 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EER23415.1 - 6.6e-08 32.0 0.0 1.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EER23415.1 - 0.021 13.5 0.0 0.072 11.7 0.0 1.9 1 0 0 1 1 1 0 tRNA synthetases class I (K) L51_S25_CI-B8 PF05047.11 EER23416.1 - 1.7e-15 56.5 0.0 3e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1751 PF08551.5 EER23417.1 - 2.4e-27 95.1 2.3 4.2e-27 94.3 1.6 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EER23417.1 - 8.4e-05 22.6 9.2 0.00017 21.6 6.4 1.4 1 0 0 1 1 1 1 Rhomboid family DUF4657 PF15552.1 EER23417.1 - 0.035 13.4 1.8 0.047 12.9 1.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) MFS_1 PF07690.11 EER23419.1 - 2.2e-25 89.1 42.4 6.1e-19 67.9 16.3 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EER23420.1 - 1.8e-13 49.8 6.6 0.0018 18.0 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EER23420.1 - 7.5e-05 22.5 0.0 0.1 12.2 0.0 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EER23420.1 - 0.038 11.8 0.0 0.055 11.2 0.0 1.3 1 0 0 1 1 1 0 IKI3 family Chorismate_bind PF00425.13 EER23421.1 - 1e-89 300.2 0.0 1.5e-89 299.7 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EER23421.1 - 3.9e-29 101.4 0.3 6.8e-26 90.9 0.0 3.2 2 1 0 2 2 2 2 Anthranilate synthase component I, N terminal region ENTH PF01417.15 EER23422.1 - 2e-49 166.6 0.0 2.8e-49 166.1 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EER23422.1 - 0.00015 20.5 0.0 0.00025 19.8 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF1510 PF07423.6 EER23422.1 - 0.013 14.8 5.1 0.8 9.0 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF1720 PF08226.6 EER23422.1 - 0.051 13.6 92.1 0.15 12.1 23.1 4.9 1 1 3 4 4 4 0 Domain of unknown function (DUF1720) DUF4264 PF14084.1 EER23422.1 - 0.13 11.6 0.1 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) UIM PF02809.15 EER23422.1 - 2.3 8.0 8.6 0.2 11.3 1.6 2.5 2 1 0 2 2 2 0 Ubiquitin interaction motif HAND PF09110.6 EER23422.1 - 7.9 6.9 15.8 1 9.7 7.8 1.9 2 0 0 2 2 2 0 HAND WD40 PF00400.27 EER23423.1 - 2e-76 249.3 13.5 9.3e-13 47.5 0.0 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EER23423.1 - 4.6e-09 34.9 1.2 0.0022 16.2 0.0 3.8 2 2 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EER23423.1 - 0.00033 19.5 0.2 1.7 7.3 0.0 3.2 2 1 0 2 2 2 2 Nup133 N terminal like bZIP_2 PF07716.10 EER23423.1 - 0.062 13.1 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Adaptin_N PF01602.15 EER23424.1 - 2.9e-05 22.5 0.1 0.12 10.7 0.0 2.3 2 0 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.17 EER23424.1 - 0.00018 21.2 2.8 2.6 8.3 0.0 6.1 7 0 0 7 7 7 1 HEAT repeat CLASP_N PF12348.3 EER23424.1 - 0.00048 19.5 0.5 0.019 14.3 0.1 3.0 2 1 0 2 2 2 1 CLASP N terminal Asp_Glu_race PF01177.17 EER23424.1 - 0.0019 18.1 0.7 0.034 14.0 0.0 2.7 2 0 0 2 2 2 1 Asp/Glu/Hydantoin racemase Exonuc_VII_L PF02601.10 EER23424.1 - 0.0026 17.0 4.3 0.0067 15.6 3.0 1.6 1 0 0 1 1 1 1 Exonuclease VII, large subunit MMS19_N PF14500.1 EER23424.1 - 0.0028 16.9 0.2 0.011 15.0 0.0 2.3 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 EER23424.1 - 0.0084 16.5 1.4 6.1 7.4 0.1 4.3 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 EER23424.1 - 0.016 15.0 0.1 0.13 12.1 0.0 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 V_ATPase_I PF01496.14 EER23424.1 - 0.11 10.2 3.0 0.18 9.6 2.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EER23424.1 - 0.24 10.9 15.9 0.011 15.3 6.6 2.0 2 0 0 2 2 2 0 IncA protein APG6 PF04111.7 EER23424.1 - 0.99 8.3 20.9 0.22 10.5 11.3 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Plasmid_stabil PF05016.9 EER23424.1 - 1.1 9.7 4.8 3.2 8.2 0.3 3.4 3 0 0 3 3 2 0 Plasmid stabilisation system protein DUF342 PF03961.8 EER23424.1 - 4.1 5.7 7.2 7.2 4.9 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TT_ORF2 PF02957.10 EER23424.1 - 5.1 7.8 7.8 4.2 8.0 3.4 2.4 2 0 0 2 2 1 0 TT viral ORF2 Macoilin PF09726.4 EER23424.1 - 5.9 5.0 10.5 11 4.1 7.3 1.3 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 EER23424.1 - 7.4 5.4 13.2 16 4.3 9.2 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Erp_C PF06780.6 EER23424.1 - 7.9 6.3 9.8 13 5.6 5.5 2.2 2 0 0 2 2 2 0 Erp protein C-terminus G-gamma PF00631.17 EER23424.1 - 8 6.2 11.7 1.5 8.5 1.3 3.6 3 0 0 3 3 3 0 GGL domain Spc7 PF08317.6 EER23424.1 - 9.6 4.7 14.4 4.6 5.8 8.1 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein Ribosomal_L7Ae PF01248.21 EER23425.1 - 8.4e-22 76.5 0.4 1.3e-21 75.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Clat_adaptor_s PF01217.15 EER23426.1 - 3.3e-43 146.7 0.0 7.5e-43 145.6 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MMR_HSR1 PF01926.18 EER23427.1 - 1.5e-21 76.5 0.0 3.5e-21 75.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EER23427.1 - 7.1e-08 32.4 0.1 0.00032 20.5 0.2 2.3 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.11 EER23427.1 - 2.7e-06 26.6 0.0 4.2e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 EER23427.1 - 0.00017 20.8 0.0 0.00025 20.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EER23427.1 - 0.00093 18.5 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EER23427.1 - 0.001 18.5 0.0 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 EER23427.1 - 0.002 17.0 0.0 0.0041 15.9 0.0 1.4 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EER23427.1 - 0.0055 15.9 0.7 0.018 14.2 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EER23427.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 EER23427.1 - 0.042 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain WD40 PF00400.27 EER23428.1 - 8.6e-56 183.9 16.7 4e-09 36.0 0.3 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.28 EER23428.1 - 1.8e-08 33.7 0.4 4.8e-08 32.4 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER23428.1 - 2e-07 30.6 0.2 5e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EER23428.1 - 9.3e-06 24.0 6.3 0.59 8.1 0.1 5.0 2 2 2 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EER23428.1 - 0.0066 15.9 0.2 6.5 6.1 0.0 2.9 2 1 1 3 3 3 2 PQQ-like domain SGL PF08450.7 EER23428.1 - 0.044 13.1 0.2 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region CPSF_A PF03178.10 EER23428.1 - 0.068 12.2 0.0 0.82 8.6 0.0 2.5 3 0 0 3 3 3 0 CPSF A subunit region HORMA PF02301.13 EER23429.1 - 5.2e-44 150.2 0.0 8.6e-44 149.5 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 EER23429.1 - 5.9e-05 22.6 9.0 0.00012 21.6 6.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EER23429.1 - 0.0012 18.1 2.8 0.0025 17.0 1.9 1.6 1 0 0 1 1 1 1 PHD-finger Cu_amine_oxid PF01179.15 EER23430.1 - 8.2e-108 360.7 0.2 1e-107 360.4 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EER23430.1 - 5.7e-26 90.2 0.0 1.3e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EER23430.1 - 5.1e-06 26.4 0.0 1.2e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Nuc_sug_transp PF04142.10 EER23432.1 - 4.3e-66 222.4 2.6 6.3e-66 221.9 1.8 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EER23432.1 - 6.5e-10 39.2 20.3 6.1e-06 26.4 2.6 2.5 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EER23432.1 - 0.00018 21.1 21.3 0.002 17.7 2.2 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EER23432.1 - 0.002 18.1 6.7 0.002 18.1 4.7 2.7 2 2 0 2 2 2 1 EamA-like transporter family UAA PF08449.6 EER23432.1 - 0.0074 15.2 13.8 0.082 11.8 9.4 2.1 1 1 0 1 1 1 1 UAA transporter family UPF0546 PF10639.4 EER23432.1 - 0.016 15.0 0.4 0.082 12.7 0.5 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Sec63 PF02889.11 EER23433.1 - 2.9e-52 177.8 0.0 5.3e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EER23433.1 - 2.9e-26 91.9 0.0 7.5e-26 90.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EER23433.1 - 3.3e-09 36.8 0.0 8.1e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EER23433.1 - 9.5e-08 31.8 0.0 3.1e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EER23433.1 - 0.0019 18.3 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EER23433.1 - 0.066 12.9 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain UvrD-helicase PF00580.16 EER23433.1 - 0.072 12.3 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HHH_5 PF14520.1 EER23433.1 - 0.093 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain Acid_PPase PF12689.2 EER23435.1 - 1.2e-68 230.0 0.0 1.4e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EER23435.1 - 0.01 16.0 0.6 0.51 10.5 0.0 2.8 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Hexapep PF00132.19 EER23436.1 - 2.6e-10 39.3 8.0 0.0057 16.1 0.0 4.7 3 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EER23436.1 - 0.0013 18.2 6.4 0.017 14.7 2.1 3.5 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Acetyltransf_1 PF00583.19 EER23437.1 - 5.7e-19 67.9 0.0 8.8e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER23437.1 - 1.1e-08 35.1 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER23437.1 - 5e-08 33.0 0.0 6.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EER23437.1 - 1e-06 28.9 0.0 1.4e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER23437.1 - 1.9e-05 24.4 0.4 5.8e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER23437.1 - 2.5e-05 24.3 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EER23437.1 - 0.00045 20.1 0.0 0.00066 19.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER23437.1 - 0.0017 18.0 0.0 0.0042 16.8 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_CG PF14542.1 EER23437.1 - 0.0039 17.0 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase TPR_MLP1_2 PF07926.7 EER23438.1 - 9.2e-33 112.7 27.1 9.2e-33 112.7 18.8 15.7 4 4 9 14 14 14 5 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EER23438.1 - 0.0008 19.1 11.0 0.0008 19.1 7.6 22.4 14 8 11 26 26 26 4 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EER23438.1 - 0.0016 18.2 7.9 0.0016 18.2 5.5 15.8 6 2 8 16 16 16 8 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.2 EER23438.1 - 0.0028 17.4 15.6 0.0028 17.4 10.8 15.5 4 4 10 16 16 16 4 Tropomyosin like TFIIE_beta PF02186.10 EER23439.1 - 1.1e-08 34.9 0.0 3.1e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF3446 PF11928.3 EER23439.1 - 0.35 11.0 4.5 0.59 10.3 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DHBP_synthase PF00926.14 EER23440.1 - 5.7e-74 247.5 0.0 3.7e-73 244.9 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase F-box-like PF12937.2 EER23441.1 - 3e-09 36.4 0.1 6e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER23441.1 - 2.8e-05 23.6 0.6 4.4e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.20 EER23442.1 - 4.1e-60 203.1 0.0 5.8e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23442.1 - 5.9e-27 94.3 0.0 8.5e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER23442.1 - 6e-09 35.2 0.0 7.7e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EER23442.1 - 0.055 12.5 0.0 0.092 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER23442.1 - 0.095 12.4 0.0 0.6 9.7 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family UQ_con PF00179.21 EER23443.1 - 6.5e-50 168.2 0.0 8.2e-50 167.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER23443.1 - 0.00076 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EER23443.1 - 0.0028 17.5 0.3 0.005 16.7 0.2 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EER23443.1 - 0.0066 16.1 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Nucleos_tra2_C PF07662.8 EER23444.1 - 1.1e-68 230.8 2.1 1.1e-68 230.8 1.4 2.9 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EER23444.1 - 2.8e-22 78.8 3.7 2.8e-22 78.8 2.6 2.9 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 EER23444.1 - 1.6 8.6 23.3 0.61 10.0 7.7 3.5 3 2 0 3 3 3 0 Nucleoside recognition AMP-binding PF00501.23 EER23445.1 - 2.3e-76 256.8 0.0 2.7e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER23445.1 - 8.7e-17 61.8 0.6 1.6e-16 60.9 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain A_deaminase PF00962.17 EER23446.1 - 4.5e-41 140.8 0.0 1.4e-40 139.2 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF2243 PF10002.4 EER23446.1 - 0.074 12.8 0.3 0.24 11.1 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2243) ATG2_CAD PF13329.1 EER23447.1 - 4.6e-49 166.0 0.0 1.3e-48 164.5 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EER23447.1 - 2.1e-30 104.7 0.1 4.8e-29 100.3 0.0 2.5 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 EER23447.1 - 0.005 16.3 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Lipase_GDSL_2 PF13472.1 EER23448.1 - 3.1e-18 66.5 0.0 9.7e-18 64.9 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EER23448.1 - 0.0012 18.6 0.0 0.0032 17.3 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CN_hydrolase PF00795.17 EER23452.1 - 1.6e-31 109.0 0.0 2.4e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ribosomal_L31e PF01198.14 EER23453.1 - 3.2e-38 129.2 1.5 4e-38 128.9 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Ran_BP1 PF00638.13 EER23454.1 - 1.1e-11 44.8 0.0 1.9e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EER23454.1 - 0.00018 21.7 25.5 0.00018 21.7 17.7 8.9 2 2 6 8 8 8 3 Nucleoporin FG repeat region SCP2 PF02036.12 EER23455.1 - 2.4e-25 88.7 0.2 2.9e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EER23455.1 - 5.8e-06 26.3 0.1 7.2e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.1 EER23455.1 - 0.11 11.8 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Ribosomal_L2_C PF03947.13 EER23457.1 - 1e-47 161.1 0.7 5.9e-34 116.6 0.5 2.4 2 0 0 2 2 2 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EER23457.1 - 7.3e-27 93.1 0.8 1.4e-26 92.2 0.6 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain HNH_2 PF13391.1 EER23459.1 - 7.3e-16 57.7 0.0 1.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Cyclin_N PF00134.18 EER23460.1 - 1.8e-43 147.1 0.1 8e-43 145.0 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EER23460.1 - 4.9e-31 107.1 0.1 1e-30 106.0 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.18 EER23462.1 - 4.7e-11 43.0 0.1 1.8e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EER23462.1 - 0.0032 17.6 0.0 0.0054 16.9 0.0 1.4 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EER23462.1 - 0.0098 15.5 0.0 0.046 13.3 0.0 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 UPF0020 PF01170.13 EER23463.1 - 3.4e-10 39.7 0.0 7.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EER23463.1 - 5.2e-10 39.3 0.0 9.1e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EER23463.1 - 3e-05 23.2 0.0 4.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase MethyltransfD12 PF02086.10 EER23463.1 - 0.14 11.6 0.5 0.35 10.2 0.1 1.8 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase DUF2985 PF11204.3 EER23464.1 - 1.8e-28 98.1 5.3 3.4e-28 97.2 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SIR2 PF02146.12 EER23465.1 - 6.9e-58 195.2 0.0 1.1e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EER23465.1 - 9.8e-06 25.1 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EER23465.1 - 0.0029 17.3 0.1 0.85 9.3 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain TPR_2 PF07719.12 EER23466.1 - 6.8e-14 50.6 0.1 6.3e-05 22.5 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EER23466.1 - 3.4e-13 49.0 0.0 1.5e-07 30.9 0.0 3.8 2 1 2 4 4 4 3 TPR repeat TPR_12 PF13424.1 EER23466.1 - 3.5e-13 49.2 0.0 1.8e-07 31.0 0.0 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER23466.1 - 1.3e-10 41.6 0.6 4.8e-05 23.8 0.1 4.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EER23466.1 - 1.4e-09 37.7 6.7 0.019 15.5 0.1 5.3 4 3 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EER23466.1 - 1.6e-09 37.9 3.8 0.058 13.7 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EER23466.1 - 1.9e-09 36.7 0.0 0.00094 18.6 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER23466.1 - 2.8e-08 32.9 0.0 0.00014 21.3 0.0 3.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER23466.1 - 1.3e-06 27.7 1.1 0.0051 16.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EER23466.1 - 9.1e-06 25.6 3.1 0.022 15.1 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EER23466.1 - 2.5e-05 24.3 0.0 0.0017 18.4 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EER23466.1 - 2.6e-05 24.3 0.5 2.1 8.9 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EER23466.1 - 0.00018 21.2 10.1 0.18 11.6 0.2 4.6 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER23466.1 - 0.00032 20.6 0.0 11 6.5 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EER23466.1 - 0.0016 18.2 8.6 1.3 9.0 0.1 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EER23466.1 - 0.0055 15.8 0.2 0.089 11.8 0.0 2.9 2 2 1 3 3 3 1 Tetratricopeptide repeat Peptidase_C50 PF03568.12 EER23466.1 - 0.037 12.7 0.1 0.07 11.7 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C50 DUF642 PF04862.7 EER23466.1 - 0.14 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF642) RWD PF05773.17 EER23467.1 - 3.6e-24 84.8 0.2 7.4e-24 83.8 0.1 1.5 1 0 0 1 1 1 1 RWD domain DUF1485 PF07364.7 EER23467.1 - 0.0041 16.3 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) RNase_H2-Ydr279 PF09468.5 EER23467.1 - 0.034 13.3 4.5 0.045 12.9 3.1 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) DHHA2 PF02833.9 EER23467.1 - 0.14 12.3 2.4 0.12 12.5 0.4 1.7 1 1 1 2 2 2 0 DHHA2 domain U79_P34 PF03064.11 EER23467.1 - 0.33 10.4 6.6 0.45 10.0 4.6 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Complex1_LYR_1 PF13232.1 EER23468.1 - 7.4e-18 64.5 0.4 1.7e-17 63.3 0.2 1.7 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EER23468.1 - 6.3e-12 45.1 0.4 1.8e-11 43.6 0.3 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) UQ_con PF00179.21 EER23469.1 - 8.9e-17 60.8 0.0 9.9e-17 60.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EER23469.1 - 0.031 14.1 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 EER23470.1 - 6e-40 136.4 3.1 6e-40 136.4 2.1 3.6 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EER23470.1 - 0.00032 20.1 4.0 0.00071 19.0 0.0 3.7 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.3 EER23470.1 - 0.0027 17.6 12.6 0.0075 16.2 0.5 4.9 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 EER23470.1 - 0.0097 15.9 3.7 0.34 11.1 0.0 4.9 6 0 0 6 6 6 1 HEAT repeat MFS_1 PF07690.11 EER23471.1 - 1.6e-28 99.4 29.8 1.6e-28 99.4 20.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Vps26 PF03643.10 EER23472.1 - 2.7e-123 410.1 0.7 6.4e-122 405.6 0.5 2.0 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EER23472.1 - 0.0015 18.3 0.3 0.65 9.7 0.0 2.8 2 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 EER23472.1 - 0.053 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) AAA_33 PF13671.1 EER23473.1 - 6.3e-15 55.2 0.0 9.2e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EER23473.1 - 1.1e-12 48.3 0.0 1.6e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EER23473.1 - 1.7e-12 47.5 0.0 2.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EER23473.1 - 2.7e-12 47.5 0.0 3.4e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EER23473.1 - 3.4e-05 23.8 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EER23473.1 - 0.00016 21.8 0.1 0.00027 21.1 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EER23473.1 - 0.00042 19.9 0.0 0.0006 19.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EER23473.1 - 0.00046 19.3 0.0 0.0012 17.9 0.0 1.7 1 1 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EER23473.1 - 0.00053 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EER23473.1 - 0.00055 20.0 0.1 0.00099 19.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EER23473.1 - 0.00075 19.3 0.0 0.0045 16.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EER23473.1 - 0.00092 18.0 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 EER23473.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Cytidylate_kin2 PF13189.1 EER23473.1 - 0.0019 18.1 0.3 0.035 14.0 0.0 2.1 1 1 0 2 2 2 1 Cytidylate kinase-like family NACHT PF05729.7 EER23473.1 - 0.0045 16.6 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EER23473.1 - 0.013 15.4 0.1 0.027 14.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain CoaE PF01121.15 EER23473.1 - 0.016 14.6 0.1 0.035 13.4 0.0 1.6 2 0 0 2 2 1 0 Dephospho-CoA kinase RNA_helicase PF00910.17 EER23473.1 - 0.018 15.1 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase tRNA_lig_kinase PF08303.6 EER23473.1 - 0.018 14.8 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_25 PF13481.1 EER23473.1 - 0.023 14.1 0.1 0.033 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EER23473.1 - 0.031 13.4 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EER23473.1 - 0.037 13.6 0.1 0.067 12.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EER23473.1 - 0.039 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.9 EER23473.1 - 0.045 13.4 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ADK PF00406.17 EER23473.1 - 0.049 13.5 0.2 0.73 9.7 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase IPT PF01745.11 EER23473.1 - 0.061 12.4 0.1 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Isopentenyl transferase T2SE PF00437.15 EER23473.1 - 0.062 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EER23473.1 - 0.065 13.5 0.2 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 ABC transporter KTI12 PF08433.5 EER23473.1 - 0.066 12.4 0.2 0.13 11.4 0.2 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 EER23473.1 - 0.066 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 EER23473.1 - 0.072 12.0 0.0 0.14 11.0 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 EER23473.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus CbiA PF01656.18 EER23473.1 - 0.11 11.8 0.1 2.2 7.6 0.0 2.1 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain VirE PF05272.6 EER23473.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E cobW PF02492.14 EER23473.1 - 0.14 11.5 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 EER23473.1 - 0.14 11.5 0.4 6.7 6.0 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.10 EER23473.1 - 0.17 11.5 0.2 0.48 10.1 0.1 1.7 2 0 0 2 2 2 0 NTPase 2-oxoacid_dh PF00198.18 EER23474.1 - 7.1e-79 264.3 0.5 1e-78 263.8 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EER23474.1 - 1.7e-15 56.3 0.0 1.7e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl PF00364.17 EER23474.1 - 4e-13 48.8 0.5 1e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme PI-PLC-X PF00388.14 EER23475.1 - 6.6e-12 45.0 0.0 1.2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 EER23476.1 - 0.0038 17.1 0.0 0.16 11.8 0.0 2.6 2 0 0 2 2 2 1 Ribosomal protein L10 Glycos_transf_3 PF00591.16 EER23477.1 - 5.3e-58 196.3 0.0 4.5e-47 160.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EER23477.1 - 1.9e-06 27.3 0.2 3.3e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Nucleoplasmin PF03066.10 EER23477.1 - 0.12 11.9 0.7 0.18 11.3 0.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EER23477.1 - 0.18 11.4 0.8 0.36 10.5 0.6 1.4 1 0 0 1 1 1 0 FAM176 family DNA_RNApol_7kD PF03604.8 EER23478.1 - 1.2e-16 59.8 6.7 1.6e-16 59.4 4.6 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit A2L_zn_ribbon PF08792.5 EER23478.1 - 0.00093 18.5 1.5 0.25 10.8 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain TFIIS_C PF01096.13 EER23478.1 - 0.0031 17.1 0.6 2 8.0 0.0 2.4 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) DZR PF12773.2 EER23478.1 - 0.0042 16.8 0.3 0.0061 16.3 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2318 PF10080.4 EER23478.1 - 0.0045 16.7 0.2 0.0048 16.6 0.1 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) GFA PF04828.9 EER23478.1 - 0.011 15.6 0.4 3.3 7.7 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme HypA PF01155.14 EER23478.1 - 0.017 14.7 0.2 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DUF2197 PF09963.4 EER23478.1 - 0.031 14.2 2.7 1.3 9.0 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Zn-ribbon_8 PF09723.5 EER23478.1 - 0.04 13.8 1.4 0.066 13.1 1.0 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Baculo_LEF5_C PF11792.3 EER23478.1 - 0.072 12.4 1.6 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Ribosomal_L40e PF01020.12 EER23478.1 - 0.08 12.5 3.4 0.12 12.0 2.4 1.2 1 0 0 1 1 1 0 Ribosomal L40e family DUF2082 PF09855.4 EER23478.1 - 0.081 12.7 1.4 0.084 12.7 0.1 1.7 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-DNL PF05180.7 EER23478.1 - 0.13 11.9 1.3 11 5.8 0.2 2.8 2 1 0 2 2 2 0 DNL zinc finger Zn_ribbon_recom PF13408.1 EER23478.1 - 0.27 11.5 5.3 3.1 8.1 1.0 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.4 EER23478.1 - 0.28 10.9 2.0 0.54 10.0 1.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 RRN7 PF11781.3 EER23478.1 - 0.39 10.2 4.1 0.42 10.1 0.2 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 EER23478.1 - 0.78 9.2 3.2 1.6 8.3 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) Fe_hyd_lg_C PF02906.9 EER23480.1 - 2.8e-61 207.2 0.0 4.7e-61 206.5 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.4 EER23481.1 - 8.6e-29 100.4 0.0 1.7e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fapy_DNA_glyco PF01149.19 EER23482.1 - 2.1e-25 89.3 0.0 4.8e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EER23482.1 - 5.6e-19 67.6 0.0 9.3e-19 66.9 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EER23482.1 - 0.0058 15.2 0.0 0.0074 14.8 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Cid2 PF09774.4 EER23483.1 - 6.1e-53 178.9 0.0 7.2e-53 178.7 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.3 EER23484.1 - 5.8e-211 701.7 12.5 1.6e-209 697.0 5.7 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.1 EER23484.1 - 2e-23 80.7 12.8 0.0008 19.8 1.0 9.8 8 1 2 10 10 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EER23484.1 - 8.4e-23 80.4 22.1 6e-05 23.2 1.3 7.3 5 1 1 6 6 6 6 Tetratricopeptide repeat TPR_11 PF13414.1 EER23484.1 - 8.4e-22 76.6 25.6 9.5e-05 21.9 1.1 7.3 7 1 0 7 7 6 5 TPR repeat TPR_2 PF07719.12 EER23484.1 - 8.4e-22 75.2 24.5 1.7e-06 27.4 0.7 10.1 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EER23484.1 - 4.5e-18 65.4 15.3 0.00052 20.5 1.3 7.8 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 EER23484.1 - 1.5e-12 46.5 26.8 2e-05 24.0 0.9 8.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 EER23484.1 - 3e-11 43.0 12.0 0.005 16.6 0.3 7.4 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EER23484.1 - 8e-11 41.2 12.7 0.74 10.1 0.0 8.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER23484.1 - 1.3e-09 37.1 11.3 0.00089 18.8 0.3 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EER23484.1 - 3.9e-08 33.1 24.7 0.0039 17.0 0.2 7.4 7 1 1 8 8 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EER23484.1 - 2.8e-07 30.5 17.0 0.08 13.0 2.5 6.1 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EER23484.1 - 1e-06 28.0 13.1 0.004 16.2 0.7 4.4 1 1 2 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EER23484.1 - 4.4e-06 26.7 17.8 0.074 13.5 0.0 7.6 8 0 0 8 8 5 2 Tetratricopeptide repeat TPR_3 PF07720.7 EER23484.1 - 9.5e-06 25.3 1.1 0.039 13.7 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER23484.1 - 2.6e-05 23.6 10.7 0.087 12.6 0.1 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat BTAD PF03704.12 EER23484.1 - 9.3e-05 22.7 6.0 0.00042 20.6 0.2 3.5 4 0 0 4 4 2 1 Bacterial transcriptional activator domain TPR_21 PF09976.4 EER23484.1 - 0.0014 18.5 0.0 0.0014 18.5 0.0 4.3 5 1 0 5 5 4 1 Tetratricopeptide repeat MIT PF04212.13 EER23484.1 - 0.0047 16.7 6.1 0.1 12.5 0.1 4.7 3 2 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_4 PF07721.9 EER23484.1 - 0.01 16.1 1.8 8.2 7.1 0.3 3.6 3 0 0 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EER23484.1 - 0.029 14.2 10.3 5.6 6.9 0.1 5.8 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_5 PF12688.2 EER23484.1 - 0.051 13.6 0.2 4.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_18 PF13512.1 EER23484.1 - 0.14 12.1 6.3 2.3 8.2 0.1 3.9 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EER23484.1 - 0.18 11.7 8.7 5.4 7.0 0.6 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_2 PF13639.1 EER23486.1 - 2.4e-15 56.0 5.5 3.9e-15 55.4 3.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EER23486.1 - 7.6e-10 38.7 2.7 2e-09 37.4 1.8 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EER23486.1 - 1.8e-08 33.8 4.3 3e-08 33.1 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER23486.1 - 2.7e-08 33.6 4.7 4.3e-08 33.0 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER23486.1 - 7e-08 32.0 3.4 1.1e-07 31.4 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EER23486.1 - 2.7e-06 26.9 3.7 4.2e-06 26.3 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EER23486.1 - 0.0004 20.1 3.9 0.0015 18.3 2.7 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EER23486.1 - 0.00068 19.2 3.9 0.0012 18.5 2.7 1.4 1 0 0 1 1 1 1 PHD-finger RINGv PF12906.2 EER23486.1 - 0.0007 19.5 4.9 0.0012 18.8 3.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 EER23486.1 - 0.0022 17.6 2.0 0.0032 17.1 0.3 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.3 EER23486.1 - 0.0023 17.4 1.4 0.0039 16.6 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EER23486.1 - 0.0035 17.1 1.7 0.0057 16.4 1.2 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EER23486.1 - 0.0075 16.1 3.4 0.016 15.0 2.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING-like PF08746.6 EER23486.1 - 0.019 14.9 4.3 0.036 14.0 3.0 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EER23486.1 - 0.026 14.0 3.5 0.043 13.3 2.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EER23486.1 - 0.033 14.0 0.1 0.05 13.4 0.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Di19 PF05605.7 EER23486.1 - 0.058 13.5 1.5 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FANCL_C PF11793.3 EER23486.1 - 0.19 11.7 6.2 1.4 8.9 4.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 EER23486.1 - 1.1 9.0 5.9 9.6 6.0 4.1 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Inhibitor_I53 PF11714.3 EER23487.1 - 0.0048 16.8 0.2 0.0092 15.9 0.1 1.4 1 0 0 1 1 1 1 Thrombin inhibitor Madanin LRR_4 PF12799.2 EER23488.1 - 2.2e-05 23.9 10.8 0.31 10.7 0.0 5.6 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EER23488.1 - 2.5e-05 23.8 5.4 2.1 8.6 0.0 5.9 6 0 0 6 6 6 1 Leucine Rich repeat LRR_1 PF00560.28 EER23488.1 - 4.4e-05 22.9 5.8 15 6.1 0.0 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_8 PF13855.1 EER23488.1 - 0.00098 18.8 7.4 0.31 10.8 0.2 4.5 4 0 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 EER23488.1 - 0.0029 17.5 4.5 72 4.2 0.0 6.1 7 0 0 7 7 7 0 Leucine rich repeat SOG2 PF10428.4 EER23489.1 - 2.3 6.7 14.7 2.4 6.7 10.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein SUZ-C PF12901.2 EER23490.1 - 0.0068 16.0 8.9 0.0068 16.0 6.1 2.7 2 0 0 2 2 2 1 SUZ-C motif SUZ PF12752.2 EER23490.1 - 0.007 16.8 7.3 0.007 16.8 5.0 5.0 3 2 1 4 4 4 1 SUZ domain GST_N_3 PF13417.1 EER23491.1 - 3.1e-24 84.9 0.0 7.2e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EER23491.1 - 1.6e-14 53.6 0.0 3.9e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER23491.1 - 2.6e-05 24.0 0.8 4.9e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EER23491.1 - 0.033 14.1 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin PAT1 PF09770.4 EER23491.1 - 0.79 7.8 18.9 1.2 7.3 13.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ATP_bind_1 PF03029.12 EER23493.1 - 4.4e-76 255.5 0.0 5.8e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EER23493.1 - 2e-05 23.5 0.0 0.0094 14.7 0.0 2.4 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 EER23493.1 - 2.9e-05 23.6 0.0 0.00042 19.8 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EER23493.1 - 5.6e-05 23.0 0.0 0.00019 21.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EER23493.1 - 0.00022 21.3 0.0 0.00081 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EER23493.1 - 0.00028 20.4 0.2 0.00056 19.4 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain Arf PF00025.16 EER23493.1 - 0.00038 19.7 0.0 0.51 9.5 0.0 3.2 3 0 0 3 3 3 1 ADP-ribosylation factor family NACHT PF05729.7 EER23493.1 - 0.00084 19.0 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 EER23493.1 - 0.0011 19.4 0.0 1.9 9.0 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 EER23493.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EER23493.1 - 0.0027 16.9 0.0 0.075 12.3 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_17 PF13207.1 EER23493.1 - 0.0032 18.2 0.1 0.017 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EER23493.1 - 0.0044 16.4 0.0 0.051 13.0 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain MobB PF03205.9 EER23493.1 - 0.0066 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EER23493.1 - 0.0074 16.6 0.1 1.9 8.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EER23493.1 - 0.0079 15.6 0.0 0.82 9.0 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EER23493.1 - 0.0083 15.0 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EER23493.1 - 0.0085 16.0 0.0 0.044 13.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EER23493.1 - 0.018 14.5 0.0 0.6 9.5 0.0 2.9 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 EER23493.1 - 0.019 14.4 0.0 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Ras PF00071.17 EER23493.1 - 0.022 14.1 0.0 3.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Ras family CbiA PF01656.18 EER23493.1 - 0.022 14.1 0.1 0.083 12.2 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 EER23493.1 - 0.032 13.7 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EER23493.1 - 0.052 12.7 0.0 4.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF87 PF01935.12 EER23493.1 - 0.078 12.7 0.4 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Pox_A32 PF04665.7 EER23493.1 - 0.11 11.7 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_18 PF13238.1 EER23493.1 - 0.24 11.7 3.4 0.43 10.9 0.0 2.9 3 1 1 4 4 4 0 AAA domain DUF2201_N PF13203.1 EER23493.1 - 1 8.4 4.0 1.6 7.8 2.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain G-alpha PF00503.15 EER23493.1 - 1 7.9 6.3 1.9 7.0 0.0 3.0 3 0 0 3 3 3 0 G-protein alpha subunit CwfJ_C_1 PF04677.10 EER23494.1 - 1.9e-31 108.2 0.0 1.4e-30 105.4 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EER23494.1 - 2.6e-26 91.9 0.0 1.2e-25 89.8 0.0 2.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 2-Hacid_dh_C PF02826.14 EER23495.1 - 2.9e-58 195.9 0.0 4e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER23495.1 - 1e-13 50.9 0.0 1.1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EER23495.1 - 0.00062 19.6 0.1 0.001 18.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EER23495.1 - 0.09 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Zn_clus PF00172.13 EER23496.1 - 1.8e-08 34.1 10.3 3.5e-08 33.2 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.7 EER23497.1 - 1.1e-08 34.4 0.5 1.9e-08 33.7 0.4 1.4 1 0 0 1 1 1 1 U1 zinc finger CAP_GLY PF01302.20 EER23498.1 - 2.8e-19 68.5 0.1 5e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EER23498.1 - 3.4e-13 48.8 16.5 2.7e-05 23.6 0.9 6.1 3 2 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EER23498.1 - 8.3e-06 25.1 7.0 14 6.4 0.0 7.4 7 0 0 7 7 7 1 Leucine rich repeat LRR_1 PF00560.28 EER23498.1 - 9.8e-05 21.8 16.8 10 6.6 0.0 7.3 6 1 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.1 EER23498.1 - 0.00016 21.3 13.9 10 6.5 0.1 7.0 7 0 0 7 7 7 2 Leucine Rich repeat LRR_8 PF13855.1 EER23498.1 - 0.0032 17.1 18.7 0.24 11.1 0.9 5.3 3 1 2 6 6 6 2 Leucine rich repeat LRR_9 PF14580.1 EER23498.1 - 0.019 14.5 3.4 0.11 12.1 0.1 3.0 3 1 0 3 3 3 0 Leucine-rich repeat zf-met PF12874.2 EER23499.1 - 2e-05 24.6 0.6 3.7e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EER23499.1 - 0.048 12.9 0.9 0.094 11.9 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.20 EER23500.1 - 2.3e-54 184.2 0.2 7.9e-38 130.0 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER23500.1 - 2.9e-24 85.5 0.5 7.5e-19 67.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EER23500.1 - 0.00013 21.0 0.0 0.00026 20.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER23500.1 - 0.00043 20.0 0.2 0.018 14.7 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EER23500.1 - 0.0013 17.8 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.19 EER23500.1 - 0.004 17.6 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 EER23500.1 - 0.03 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3441 PF11923.3 EER23500.1 - 0.096 12.2 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3441) RIO1 PF01163.17 EER23500.1 - 0.2 11.0 1.6 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 EER23501.1 - 1.1e-16 61.2 0.0 8.2e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EER23501.1 - 0.00079 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF1679 PF07914.6 EER23501.1 - 0.046 12.3 0.0 0.24 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Tim54 PF11711.3 EER23502.1 - 1.2e-138 461.9 0.1 1.4e-138 461.7 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 EER23503.1 - 8.8e-25 87.3 0.0 3.9e-24 85.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23503.1 - 1.2e-09 37.6 0.8 0.00037 19.6 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EER23503.1 - 0.0036 16.3 0.0 2.2 7.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EER23503.1 - 0.15 11.7 1.6 0.22 11.2 0.4 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family BSD PF03909.12 EER23504.1 - 3.3e-24 84.4 8.9 4.5e-14 51.9 0.3 2.9 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EER23504.1 - 2.4e-21 75.1 0.0 6.2e-21 73.8 0.0 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain B12-binding_2 PF02607.12 EER23504.1 - 0.096 12.7 0.0 0.4 10.7 0.0 2.1 1 1 0 1 1 1 0 B12 binding domain Crystallin PF00525.13 EER23504.1 - 0.15 12.2 0.3 0.56 10.4 0.2 1.9 1 1 0 1 1 1 0 Alpha crystallin A chain, N terminal ING PF12998.2 EER23506.1 - 1.5e-09 38.0 0.0 3.6e-09 36.8 0.0 1.6 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EER23506.1 - 1.6e-09 37.2 8.0 2.5e-09 36.6 5.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EER23506.1 - 0.08 13.1 1.2 0.18 11.9 0.9 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 EER23506.1 - 0.49 9.7 2.7 0.85 8.9 1.9 1.4 1 0 0 1 1 1 0 PHD-finger Transket_pyr PF02779.19 EER23507.1 - 2e-64 216.3 0.0 3.4e-64 215.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EER23507.1 - 2.6e-55 187.2 0.0 3.5e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Sld5 PF05916.6 EER23510.1 - 1.7e-13 50.7 0.0 2.1e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Microtub_assoc PF07989.6 EER23511.1 - 4.5e-05 23.1 7.3 9.1e-05 22.2 5.0 1.5 1 0 0 1 1 1 1 Microtubule associated DUF904 PF06005.7 EER23511.1 - 0.0019 18.4 8.2 0.0035 17.5 5.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF904) Phage_GP20 PF06810.6 EER23511.1 - 0.013 14.9 2.5 0.026 13.9 1.7 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3825 PF12873.2 EER23511.1 - 0.018 14.2 0.1 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) IncA PF04156.9 EER23511.1 - 0.041 13.4 4.0 0.081 12.5 2.8 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EER23511.1 - 0.14 11.6 7.0 0.17 11.4 3.8 1.9 1 1 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.16 EER23511.1 - 0.14 12.1 6.5 0.4 10.6 4.5 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF342 PF03961.8 EER23511.1 - 0.19 10.1 3.4 0.27 9.5 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Prominin PF05478.6 EER23511.1 - 0.27 8.7 0.6 0.4 8.1 0.4 1.1 1 0 0 1 1 1 0 Prominin Bacillus_HBL PF05791.6 EER23511.1 - 0.35 10.2 3.5 0.44 9.8 0.9 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Tropomyosin_1 PF12718.2 EER23511.1 - 0.49 10.2 7.4 0.83 9.5 5.2 1.3 1 0 0 1 1 1 0 Tropomyosin like DUF972 PF06156.8 EER23511.1 - 3.1 8.2 7.0 8.6 6.7 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Sod_Fe_C PF02777.13 EER23512.1 - 2.5e-39 133.3 0.2 4.2e-39 132.6 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EER23512.1 - 8.4e-30 102.8 1.2 1.4e-29 102.1 0.9 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GCFC PF07842.7 EER23513.1 - 4.9e-79 265.5 5.4 8.3e-79 264.8 3.8 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EER23513.1 - 4.3e-15 55.2 0.9 8.5e-15 54.2 0.6 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EER23513.1 - 1.4e-07 31.2 0.5 4.7e-07 29.5 0.4 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site FUSC PF04632.7 EER23513.1 - 0.2 10.0 0.2 0.43 8.9 0.2 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C4H2 PF10146.4 EER23513.1 - 0.86 9.5 7.3 0.14 12.1 1.9 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein DUF1162 PF06650.7 EER23514.1 - 8.8e-86 287.5 0.0 2.3e-83 279.6 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EER23514.1 - 3.5e-43 145.8 0.1 1.2e-42 144.1 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EER23514.1 - 7.8e-06 25.9 0.0 3.8e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 ATG C terminal domain ATG22 PF11700.3 EER23515.1 - 9.9e-108 360.6 23.6 1.1e-107 360.4 16.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Cytochrom_B558a PF05038.8 EER23515.1 - 0.094 12.3 0.2 0.094 12.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Phage_holin_3 PF05106.7 EER23515.1 - 1.5 8.8 6.2 0.2 11.6 0.2 2.5 3 0 0 3 3 3 0 Phage holin family (Lysis protein S) MFS_1 PF07690.11 EER23515.1 - 2.9 6.5 34.6 0.84 8.2 13.1 2.6 2 2 0 2 2 2 0 Major Facilitator Superfamily DUF3429 PF11911.3 EER23516.1 - 4.3e-42 143.4 10.0 6.4e-42 142.8 6.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.11 EER23517.1 - 4.6e-71 238.5 0.3 8.4e-71 237.6 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EER23517.1 - 9.1e-65 218.3 0.0 1.2e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EER23517.1 - 0.00061 19.1 0.1 0.079 12.2 0.0 2.2 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.13 EER23518.1 - 9.8e-66 221.2 0.2 1.9e-65 220.2 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EER23518.1 - 9e-43 145.6 0.0 2.5e-42 144.1 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER23518.1 - 3.2e-06 27.2 0.5 1.3e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EER23518.1 - 3.6e-06 27.7 0.2 4e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EER23518.1 - 1.2e-05 25.0 0.0 4.1e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EER23518.1 - 9.6e-05 21.2 0.0 9.6e-05 21.2 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 EER23518.1 - 0.00028 21.0 2.7 0.0056 16.8 0.2 3.1 3 1 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EER23518.1 - 0.00061 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EER23518.1 - 0.0012 18.3 1.3 0.057 12.8 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EER23518.1 - 0.0015 18.2 0.3 0.0048 16.6 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EER23518.1 - 0.002 17.5 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EER23518.1 - 0.0021 17.9 0.0 0.0056 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EER23518.1 - 0.0068 15.5 0.8 0.025 13.7 0.2 2.0 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EER23518.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EER23518.1 - 0.016 15.1 0.0 0.05 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EER23518.1 - 0.021 14.0 0.2 0.04 13.0 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EER23518.1 - 0.026 14.5 1.4 0.044 13.7 0.0 2.2 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.8 EER23518.1 - 0.026 13.4 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.7 EER23518.1 - 0.034 13.7 2.2 1.2 8.8 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.1 EER23518.1 - 0.042 14.1 0.1 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTP_transferase PF00483.18 EER23520.1 - 4.1e-48 163.8 0.0 8.2e-48 162.8 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EER23520.1 - 7.7e-17 59.9 18.1 1.8e-09 36.6 1.2 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EER23520.1 - 1.5e-09 38.1 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EER23520.1 - 9.4e-07 28.2 1.1 9.4e-07 28.2 0.8 3.1 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase dTMP_synthase PF02593.9 EER23520.1 - 0.086 12.1 0.1 2.3 7.5 0.0 2.1 1 1 1 2 2 2 0 Thymidylate synthase IspD PF01128.14 EER23520.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.20 EER23521.1 - 2.3e-05 24.3 0.1 0.00017 21.5 0.2 2.3 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EER23521.1 - 0.00085 19.0 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 KR domain zf-H2C2_2 PF13465.1 EER23522.1 - 3.9e-15 55.2 32.3 1.5e-07 31.3 0.2 5.2 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EER23522.1 - 7.7e-13 47.9 34.4 5.2e-05 23.3 1.5 4.7 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER23522.1 - 3.4e-05 23.8 28.3 0.0071 16.5 1.9 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger Suc_Fer-like PF06999.7 EER23523.1 - 2e-35 122.8 0.0 4.8e-35 121.6 0.0 1.6 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Ribosomal_S13_N PF08069.7 EER23523.1 - 0.078 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain 2-Hacid_dh_C PF02826.14 EER23524.1 - 6.3e-43 145.9 0.0 1e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER23524.1 - 1.4e-07 31.0 0.0 2.3e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain DUF4129 PF13559.1 EER23525.1 - 0.009 15.9 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) DUF3857 PF12969.2 EER23525.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) PH_10 PF15411.1 EER23526.1 - 4.4e-41 139.6 0.0 8.4e-41 138.7 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EER23526.1 - 3.1e-34 116.8 0.0 6.5e-34 115.8 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EER23526.1 - 2.1e-30 105.9 1.7 3.8e-30 105.1 1.2 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EER23526.1 - 1e-07 31.5 0.1 3.7e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 PB1 domain 4_1_CTD PF05902.8 EER23526.1 - 0.13 12.3 0.1 0.39 10.7 0.1 1.8 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) Pox_Rif PF03340.8 EER23526.1 - 0.13 10.2 0.0 0.2 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus rifampicin resistance protein WD40 PF00400.27 EER23527.1 - 1.4e-42 142.0 10.7 5.9e-07 29.1 0.0 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EER23527.1 - 8e-14 51.1 0.6 1.9e-13 49.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER23527.1 - 2.3e-08 33.4 0.0 5e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EER23527.1 - 0.03 12.4 11.8 0.45 8.5 0.0 3.9 4 1 0 5 5 5 0 Nucleoporin Nup120/160 MgtE_N PF03448.12 EER23527.1 - 0.037 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain DUF605 PF04652.11 EER23527.1 - 0.15 11.4 17.3 0.23 10.8 12.0 1.2 1 0 0 1 1 1 0 Vta1 like Uds1 PF15456.1 EER23529.1 - 2.3e-41 140.6 7.4 2.3e-41 140.6 5.1 6.5 3 2 2 5 5 5 1 Up-regulated During Septation MFS_1 PF07690.11 EER23530.1 - 5.8e-22 77.8 27.5 9.6e-22 77.1 19.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UCR_hinge PF02320.11 EER23531.1 - 6.3e-24 83.7 5.6 1.3e-23 82.7 3.9 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein WWbp PF10349.4 EER23531.1 - 7.3e-21 75.2 3.1 7.3e-21 75.2 2.2 2.6 2 0 0 2 2 2 1 WW-domain ligand protein DUF4211 PF13926.1 EER23531.1 - 0.0089 15.4 0.8 0.02 14.2 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) Ribosomal_60s PF00428.14 EER23531.1 - 0.04 14.3 15.4 0.077 13.3 10.7 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein PRCC PF10253.4 EER23531.1 - 1 10.0 11.5 6 7.5 3.5 2.8 3 0 0 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting Sigma70_ner PF04546.8 EER23531.1 - 2.1 7.8 9.5 0.48 10.0 4.3 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region RR_TM4-6 PF06459.7 EER23531.1 - 9.6 6.0 11.4 17 5.1 7.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3461 PF11944.3 EER23532.1 - 0.081 12.7 3.9 0.16 11.8 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3461) Phage_GP20 PF06810.6 EER23532.1 - 0.16 11.4 8.0 0.66 9.4 5.5 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 TnpV PF14198.1 EER23532.1 - 0.34 10.8 5.0 0.56 10.1 3.2 1.6 1 1 0 1 1 1 0 Transposon-encoded protein TnpV Tmemb_cc2 PF10267.4 EER23532.1 - 1.5 7.3 10.8 2 6.9 6.9 1.8 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Acyltransferase PF01553.16 EER23533.1 - 2e-10 40.2 0.0 0.00054 19.4 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Prenyltransf PF01255.14 EER23534.1 - 3.8e-83 277.9 0.0 5.6e-83 277.4 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 EER23535.1 - 3.7e-128 427.7 0.0 5.3e-128 427.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EER23535.1 - 3.8e-06 27.0 0.1 5.7e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EER23535.1 - 5.1e-05 23.3 0.2 0.00013 22.0 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding DUF2325 PF10087.4 EER23535.1 - 0.0019 17.9 0.1 0.0034 17.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2325) NAD_binding_7 PF13241.1 EER23535.1 - 0.043 14.0 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 EER23535.1 - 0.059 12.7 0.2 0.66 9.3 0.0 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain ADH_zinc_N_2 PF13602.1 EER23536.1 - 8e-19 68.7 0.0 2.7e-18 67.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EER23536.1 - 3.5e-11 42.7 0.0 5.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_15 PF00723.16 EER23537.1 - 4.8e-100 335.2 0.0 5.7e-100 334.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EER23537.1 - 1.2e-31 108.1 0.0 2.8e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Aha1_N PF09229.6 EER23538.1 - 7e-39 132.7 1.0 8.8e-39 132.4 0.2 1.5 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EER23538.1 - 7.4e-16 58.3 0.4 7.4e-16 58.3 0.3 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 EER23538.1 - 0.035 14.2 0.4 0.058 13.5 0.3 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Mucin PF01456.12 EER23538.1 - 1 9.1 9.0 1.8 8.3 6.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein BAR PF03114.13 EER23539.1 - 0.72 9.3 13.6 0.01 15.3 3.6 2.1 3 0 0 3 3 3 0 BAR domain OmpH PF03938.9 EER23539.1 - 5.4 6.9 12.0 11 5.9 8.3 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FBPase PF00316.15 EER23540.1 - 2.1e-117 391.5 0.0 2.4e-117 391.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase adh_short PF00106.20 EER23541.1 - 7.5e-31 107.2 0.0 9.1e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER23541.1 - 2.2e-22 79.9 0.0 2.8e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER23541.1 - 1.1e-10 41.4 0.1 1.6e-10 40.9 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EER23541.1 - 1e-05 25.1 0.0 1.4e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EER23541.1 - 0.00054 19.0 0.2 0.0057 15.7 0.0 2.4 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EER23541.1 - 0.0015 18.2 1.3 0.0035 17.0 0.9 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1815 PF08844.5 EER23541.1 - 0.0064 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1815) Glyco_transf_5 PF08323.6 EER23541.1 - 0.039 13.4 0.0 0.19 11.1 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain RmlD_sub_bind PF04321.12 EER23541.1 - 0.097 11.5 0.2 0.36 9.6 0.0 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain V_ATPase_I PF01496.14 EER23542.1 - 4.4e-296 983.7 0.2 5e-296 983.6 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Filament PF00038.16 EER23542.1 - 0.19 11.1 3.7 4.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Intermediate filament protein MOSC PF03473.12 EER23543.1 - 1.8e-05 24.2 0.3 5.8e-05 22.5 0.2 1.8 1 1 0 1 1 1 1 MOSC domain DUF3437 PF11919.3 EER23544.1 - 2.1e-31 107.4 0.0 6.9e-31 105.8 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EER23544.1 - 0.00019 21.2 0.4 1.3 9.2 0.0 5.3 4 0 0 4 4 4 1 HEAT repeat CLASP_N PF12348.3 EER23544.1 - 0.067 12.5 0.2 7.7 5.8 0.0 3.0 2 0 0 2 2 2 0 CLASP N terminal Mannosyl_trans2 PF04188.8 EER23545.1 - 3.2e-62 210.8 12.2 3.9e-62 210.6 8.5 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) Pro_CA PF00484.14 EER23547.1 - 2e-43 148.0 0.0 3e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase GFO_IDH_MocA PF01408.17 EER23548.1 - 8.3e-17 61.8 0.0 1.4e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF1814 PF08843.6 EER23549.1 - 0.026 14.3 0.1 0.08 12.7 0.0 1.8 1 1 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) UPF0104 PF03706.8 EER23550.1 - 0.018 14.2 0.1 0.022 14.0 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF443 PF04276.7 EER23550.1 - 0.026 13.9 0.9 0.036 13.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Thiolase_N PF00108.18 EER23551.1 - 3.4e-79 265.5 4.1 6e-79 264.7 2.8 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EER23551.1 - 6.5e-45 151.5 0.3 1.4e-44 150.4 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EER23551.1 - 0.00054 19.9 0.0 0.0021 18.0 0.0 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Methyltransf_6 PF03737.10 EER23552.1 - 4.7e-21 75.2 0.2 9.2e-21 74.3 0.2 1.5 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase CAF-1_p150 PF11600.3 EER23553.1 - 4.2e-07 29.5 60.4 4.2e-07 29.5 41.9 3.5 4 0 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDRGK PF09756.4 EER23553.1 - 0.53 9.6 45.3 1.1 8.5 31.4 1.5 1 0 0 1 1 1 0 DDRGK domain Borrelia_P83 PF05262.6 EER23553.1 - 5.2 5.2 35.8 12 4.0 24.8 1.5 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.10 EER23553.1 - 5.4 5.5 20.7 4.8 5.7 10.9 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Velvet PF11754.3 EER23554.1 - 4.5e-61 206.0 0.8 3.1e-60 203.2 0.6 1.9 1 1 0 1 1 1 1 Velvet factor MOZ_SAS PF01853.13 EER23555.1 - 5.6e-78 260.5 0.0 8.1e-78 259.9 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EER23555.1 - 0.32 10.7 20.0 0.1 12.3 11.0 2.2 2 0 0 2 2 2 0 PHD-finger zf-MIZ PF02891.15 EER23555.1 - 2.2 7.8 8.2 5.6 6.5 5.7 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PetG PF02529.10 EER23556.1 - 0.16 11.5 0.3 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 Acetyltransf_2 PF00797.12 EER23557.1 - 4.1e-39 134.6 0.0 5.1e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase PsbN PF02468.10 EER23557.1 - 0.063 12.8 0.1 13 5.4 0.0 2.4 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) YTH PF04146.10 EER23559.1 - 2.8e-34 117.7 0.0 4.4e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain Drf_GBD PF06371.8 EER23560.1 - 2.6e-18 66.0 2.7 3.5e-16 59.1 1.9 2.5 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EER23560.1 - 0.003 16.9 0.0 0.0067 15.8 0.0 1.5 1 0 0 1 1 1 1 Diaphanous FH3 Domain CRM1_C PF08767.6 EER23560.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 CRM1 C terminal Nramp PF01566.13 EER23561.1 - 1.1e-89 300.6 20.3 1.1e-89 300.6 14.1 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Snf7 PF03357.16 EER23562.1 - 2.7e-40 137.5 14.0 3.2e-40 137.2 9.7 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EER23562.1 - 7.4e-05 22.2 5.1 7.4e-05 22.2 3.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) DUF848 PF05852.6 EER23562.1 - 0.0013 18.6 5.1 0.004 17.0 3.0 2.0 2 1 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) NPV_P10 PF05531.7 EER23562.1 - 0.0024 18.1 9.0 0.11 12.7 1.5 3.0 3 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EER23562.1 - 0.0058 15.8 3.0 0.23 10.5 0.3 2.1 1 1 0 2 2 2 1 Reovirus sigma C capsid protein Zwint PF15556.1 EER23562.1 - 0.014 14.6 5.3 0.021 14.1 3.7 1.3 1 0 0 1 1 1 0 ZW10 interactor Tropomyosin_1 PF12718.2 EER23562.1 - 0.022 14.6 7.6 0.13 12.0 0.3 2.3 1 1 1 2 2 2 0 Tropomyosin like Atg14 PF10186.4 EER23562.1 - 0.07 12.0 8.6 0.095 11.6 5.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 EER23562.1 - 0.079 12.8 7.8 3.5 7.6 0.0 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Y_phosphatase3C PF13348.1 EER23562.1 - 0.092 12.8 0.0 0.57 10.3 0.0 2.4 2 1 0 2 2 2 0 Tyrosine phosphatase family C-terminal region Exonuc_VII_L PF02601.10 EER23562.1 - 0.1 11.7 2.5 0.13 11.4 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 EER23562.1 - 0.11 10.8 6.8 1.6 7.0 4.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Laminin_II PF06009.7 EER23562.1 - 0.14 11.9 7.0 1.2 8.9 0.4 2.3 1 1 1 2 2 2 0 Laminin Domain II CDC37_N PF03234.9 EER23562.1 - 0.14 12.4 7.4 0.19 12.0 5.1 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Sec34 PF04136.10 EER23562.1 - 0.24 11.1 3.8 0.3 10.7 1.2 1.9 1 1 1 2 2 2 0 Sec34-like family RILP PF11461.3 EER23562.1 - 0.25 11.5 2.2 0.44 10.7 0.1 2.4 2 1 0 2 2 2 0 Rab interacting lysosomal protein TBPIP PF07106.8 EER23562.1 - 0.36 10.3 12.9 0.9 9.0 1.0 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 EER23562.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.7 3 1 1 4 4 4 0 Prefoldin subunit Baculo_PEP_C PF04513.7 EER23562.1 - 0.49 10.2 5.3 8.8 6.1 1.2 2.4 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EER23562.1 - 0.51 9.9 8.7 1.6 8.3 1.8 2.3 1 1 1 2 2 2 0 IncA protein APG6 PF04111.7 EER23562.1 - 0.76 8.7 8.5 0.42 9.6 4.5 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF4140 PF13600.1 EER23562.1 - 0.92 9.9 8.3 1.1 9.6 0.0 3.4 2 1 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.1 EER23562.1 - 1 9.1 4.8 0.48 10.2 1.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) OmpH PF03938.9 EER23562.1 - 1.4 8.8 12.5 1.2 9.0 5.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) BLOC1_2 PF10046.4 EER23562.1 - 1.5 9.0 8.8 10 6.3 0.4 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.13 EER23562.1 - 3.5 8.0 9.1 16 5.9 3.2 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus COG2 PF06148.6 EER23562.1 - 9.8 6.0 7.5 12 5.7 0.7 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SAPS PF04499.10 EER23563.1 - 2.5e-150 501.2 0.0 1.8e-114 382.9 0.0 2.9 3 1 1 4 4 4 2 SIT4 phosphatase-associated protein Complex1_51K PF01512.12 EER23565.1 - 2.2e-47 160.5 0.0 3.8e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EER23565.1 - 2.2e-18 65.1 1.0 2.2e-18 65.1 0.7 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EER23565.1 - 4.2e-09 36.1 0.0 1e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 SLBB domain TSA PF03249.8 EER23565.1 - 0.78 8.2 3.8 1.3 7.4 2.7 1.2 1 0 0 1 1 1 0 Type specific antigen DUF4106 PF13388.1 EER23565.1 - 3.9 6.3 7.5 5.7 5.7 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Nup96 PF12110.3 EER23566.1 - 2.2e-82 276.4 0.0 3.3e-82 275.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EER23566.1 - 2.9e-49 166.5 0.0 4.8e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EER23566.1 - 0.0011 19.1 47.3 0.0011 19.1 32.8 8.7 5 2 5 10 10 10 4 Nucleoporin FG repeat region AMP-binding PF00501.23 EER23567.1 - 7.3e-92 307.9 0.1 9e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER23567.1 - 5.3e-23 81.7 0.1 8.4e-21 74.7 0.2 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GET2 PF08690.5 EER23568.1 - 9e-06 25.1 0.4 1.3e-05 24.6 0.3 1.3 1 1 0 1 1 1 1 GET complex subunit GET2 C2 PF00168.25 EER23569.1 - 2.1e-18 65.9 0.0 4.5e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 C2 domain DUF3144 PF11342.3 EER23569.1 - 0.048 13.7 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) CDC45 PF02724.9 EER23570.1 - 0.21 9.6 3.4 0.29 9.1 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein IMS_C PF11799.3 EER23571.1 - 5.7e-09 35.9 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS PF00817.15 EER23571.1 - 6.4e-06 26.0 0.0 1.4e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family Reprolysin_5 PF13688.1 EER23572.1 - 3e-63 213.3 0.1 7.7e-63 211.9 0.1 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EER23572.1 - 2.1e-48 164.5 0.0 3.9e-48 163.7 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EER23572.1 - 2.8e-48 164.2 1.1 9.9e-48 162.4 0.0 2.3 3 0 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EER23572.1 - 7.8e-19 67.6 32.3 7.8e-19 67.6 22.4 4.4 2 1 2 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 EER23572.1 - 8.2e-19 68.3 0.0 2.2e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like EF-hand_7 PF13499.1 EER23573.1 - 3.3e-15 55.9 0.2 7.9e-09 35.5 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EER23573.1 - 1.1e-14 52.4 1.4 3.8e-05 22.6 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EER23573.1 - 2.1e-14 52.0 4.0 5.3e-06 25.8 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EER23573.1 - 8.8e-12 44.4 1.6 2.3e-09 36.7 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EER23573.1 - 0.039 13.3 6.1 0.7 9.3 0.1 2.9 3 0 0 3 3 3 0 EF hand EF-hand_4 PF12763.2 EER23573.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EER23573.1 - 0.17 11.8 0.1 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand KH_1 PF00013.24 EER23574.1 - 1.8e-42 142.7 12.7 1.1e-13 50.6 2.7 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EER23574.1 - 2.6e-32 109.8 10.7 5.5e-11 41.8 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EER23574.1 - 1.7e-13 49.8 1.4 0.0018 17.7 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EER23574.1 - 1.3e-09 37.5 4.0 0.025 14.2 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EER23574.1 - 0.0001 22.0 2.1 0.74 9.6 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EER23574.1 - 0.11 11.9 0.0 4.2 6.8 0.0 2.9 3 0 0 3 3 3 0 dUTPase Aminotran_1_2 PF00155.16 EER23575.1 - 1.1e-55 189.0 0.0 4e-55 187.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II MgsA_C PF12002.3 EER23576.1 - 4.7e-58 195.5 0.0 8.1e-58 194.8 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EER23576.1 - 1.2e-13 51.4 0.1 2.8e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EER23576.1 - 2.8e-11 42.9 0.0 6.4e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EER23576.1 - 3.8e-05 22.9 0.1 0.11 11.6 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EER23576.1 - 5.8e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EER23576.1 - 6.7e-05 22.6 0.1 0.00091 18.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EER23576.1 - 7.5e-05 22.2 0.1 0.0052 16.2 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EER23576.1 - 0.00033 20.2 0.0 0.00091 18.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EER23576.1 - 0.0024 16.8 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EER23576.1 - 0.0031 17.6 0.2 0.015 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EER23576.1 - 0.0041 17.1 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EER23576.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER23576.1 - 0.015 15.3 0.1 0.56 10.1 0.0 2.6 1 1 1 2 2 2 0 AAA ATPase domain ResIII PF04851.10 EER23576.1 - 0.02 14.7 0.4 3.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EER23576.1 - 0.022 15.5 0.0 0.054 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EER23576.1 - 0.022 14.3 0.2 0.11 12.0 0.2 1.8 1 1 1 2 2 2 0 AAA domain TIP49 PF06068.8 EER23576.1 - 0.024 13.3 0.2 0.046 12.4 0.1 1.4 1 1 0 1 1 1 0 TIP49 C-terminus SKI PF01202.17 EER23576.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_29 PF13555.1 EER23576.1 - 0.091 12.3 0.1 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-C2H2 PF00096.21 EER23576.1 - 0.098 13.0 0.1 0.27 11.6 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sgf11 PF08209.6 EER23576.1 - 0.12 11.6 0.2 0.25 10.6 0.1 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) AAA_18 PF13238.1 EER23576.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 EER23576.1 - 0.18 10.6 0.1 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Zn_clus PF00172.13 EER23577.1 - 0.031 14.1 11.3 0.072 13.0 7.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EFG_II PF14492.1 EER23577.1 - 0.17 11.7 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Elongation Factor G, domain II Ald_Xan_dh_C2 PF02738.13 EER23580.1 - 7.7e-200 664.8 0.4 1e-199 664.4 0.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EER23580.1 - 2.4e-45 154.0 0.0 4.2e-45 153.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EER23580.1 - 2.9e-34 117.1 0.0 3.4e-33 113.6 0.0 2.8 3 0 0 3 3 3 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EER23580.1 - 2.8e-29 100.8 0.0 6.1e-29 99.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Ald_Xan_dh_C PF01315.17 EER23580.1 - 1.2e-28 99.3 0.0 3.2e-28 98.0 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2 PF00111.22 EER23580.1 - 1.4e-08 34.3 0.1 1.4e-08 34.3 0.1 2.6 2 1 1 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Sigma70_r4 PF04545.11 EER23580.1 - 0.13 11.5 0.0 0.35 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 AMP-binding PF00501.23 EER23582.1 - 6.8e-72 242.1 0.0 1.1e-71 241.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EER23582.1 - 1.3e-68 230.6 0.0 1.9e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EER23582.1 - 6.5e-11 42.1 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EER23582.1 - 1.7e-10 40.9 0.0 3.4e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EER23582.1 - 5e-09 36.9 0.0 2.4e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EER23582.1 - 6.2e-05 21.8 0.0 0.00014 20.6 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EER23582.1 - 0.00018 21.5 0.0 0.0043 17.0 0.0 2.6 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EER23582.1 - 0.065 12.1 0.0 0.7 8.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain ABC_tran PF00005.22 EER23583.1 - 0.00064 20.0 0.0 0.0015 18.8 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EER23583.1 - 0.0026 18.5 0.0 0.0058 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EER23583.1 - 0.004 17.4 0.1 0.11 12.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EER23583.1 - 0.023 14.2 0.1 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CPT PF07931.7 EER23583.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PRK PF00485.13 EER23583.1 - 0.098 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EER23583.1 - 0.1 12.5 1.2 0.31 10.9 0.1 2.2 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EER23583.1 - 0.11 12.5 5.1 3.4 7.6 3.6 2.7 1 1 0 1 1 1 0 AAA ATPase domain SNF2_N PF00176.18 EER23584.1 - 5.3e-36 123.9 0.1 6.2e-31 107.3 0.0 2.7 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EER23584.1 - 0.0034 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MFS_1 PF07690.11 EER23585.1 - 1.9e-43 148.5 34.4 1e-40 139.5 14.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Mid2 PF04478.7 EER23586.1 - 5.3e-05 22.6 0.2 8.5e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EER23586.1 - 0.00093 18.4 0.2 0.0027 16.9 0.1 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain HMG_box PF00505.14 EER23587.1 - 1.5e-23 82.7 0.4 3e-23 81.8 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EER23587.1 - 4.7e-09 36.4 0.1 1e-08 35.4 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain DUF1908 PF08926.6 EER23587.1 - 0.83 8.3 4.4 1.9 7.1 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Lipase_GDSL PF00657.17 EER23588.1 - 0.00027 20.8 0.0 0.0031 17.3 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ribosomal_S6e PF01092.14 EER23589.1 - 7.4e-59 196.9 0.1 1.6e-58 195.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 EER23590.1 - 4.8e-46 155.2 0.5 9.6e-45 151.0 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EER23590.1 - 2.9e-43 147.7 2.0 1.3e-36 126.0 0.6 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EER23590.1 - 5.2e-13 48.8 0.4 2.9e-11 43.1 0.2 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EER23590.1 - 0.005 16.0 0.2 0.0088 15.2 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase IF-2B PF01008.12 EER23590.1 - 0.034 13.1 0.1 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF913 PF06025.7 EER23591.1 - 1.1e-126 422.6 2.8 4.9e-126 420.5 0.0 3.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EER23591.1 - 3.3e-96 322.1 0.1 5.3e-96 321.4 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EER23591.1 - 4.9e-88 295.5 0.2 4.9e-88 295.5 0.2 3.2 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EER23591.1 - 8e-33 112.5 8.2 8e-33 112.5 5.7 3.9 4 1 0 4 4 4 1 Domain of unknown function (DUF4414) UBA PF00627.26 EER23591.1 - 0.00055 19.6 0.0 0.0022 17.8 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain An_peroxidase PF03098.10 EER23592.1 - 3.7e-100 335.8 0.0 8.4e-81 271.9 0.0 2.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EER23592.1 - 6.2e-08 31.5 0.0 1.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Steroid_dh PF02544.11 EER23593.1 - 4.1e-32 111.0 0.6 5.6e-32 110.5 0.4 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EER23593.1 - 1.6e-06 27.6 0.2 2.4e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EER23593.1 - 2e-06 27.8 0.3 3.6e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase Glyco_transf_34 PF05637.7 EER23594.1 - 1.1e-61 208.4 0.0 1.4e-61 208.0 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L28 PF00830.14 EER23595.1 - 1.9e-19 69.2 0.2 3.2e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.8 EER23596.1 - 5.8e-187 621.2 0.3 6.7e-187 621.0 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EER23596.1 - 1.9e-11 43.5 1.8 5.3e-07 28.9 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EER23596.1 - 2.7e-11 43.8 0.3 3.1e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER23596.1 - 5.3e-06 26.5 0.0 0.009 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EER23596.1 - 1.2e-05 25.4 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EER23596.1 - 6.7e-05 22.5 0.0 0.0002 21.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EER23596.1 - 0.00018 21.5 0.1 0.00047 20.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER23596.1 - 0.00048 19.8 0.2 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EER23596.1 - 0.00077 18.6 0.3 0.002 17.2 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EER23596.1 - 0.00078 18.9 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EER23596.1 - 0.00078 18.9 0.1 0.61 9.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 EER23596.1 - 0.0076 15.6 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EER23596.1 - 0.011 14.9 0.1 0.53 9.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EER23596.1 - 0.015 14.2 0.1 0.035 13.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EER23596.1 - 0.02 15.2 0.2 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EER23596.1 - 0.02 13.9 0.3 0.098 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.10 EER23596.1 - 0.022 13.6 0.0 0.047 12.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EER23596.1 - 0.063 14.1 0.1 0.15 12.8 0.0 1.9 2 1 0 2 2 1 0 AAA domain NACHT PF05729.7 EER23596.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NAD_binding_8 PF13450.1 EER23597.1 - 3.1e-09 36.7 0.0 7.3e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EER23597.1 - 0.00065 18.7 0.0 0.00098 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FMO-like PF00743.14 EER23597.1 - 0.044 11.9 0.0 0.063 11.4 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 EER23597.1 - 0.052 13.9 0.1 0.33 11.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER23597.1 - 0.059 13.1 0.3 0.59 9.9 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EER23597.1 - 0.26 10.1 0.2 0.42 9.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EER23597.1 - 0.28 9.6 0.0 0.41 9.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein V-SNARE PF05008.10 EER23598.1 - 4.9e-22 77.8 5.4 4.9e-22 77.8 3.7 1.9 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EER23598.1 - 9.3e-17 60.8 3.1 9.3e-17 60.8 2.1 3.4 3 1 1 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus Fusion_gly PF00523.13 EER23598.1 - 0.0067 14.5 2.0 0.15 10.0 0.1 2.2 2 0 0 2 2 2 2 Fusion glycoprotein F0 Sec20 PF03908.8 EER23598.1 - 0.0073 15.9 1.5 0.014 15.0 0.1 2.2 2 2 0 2 2 2 1 Sec20 COG7 PF10191.4 EER23598.1 - 0.0088 14.0 1.0 0.013 13.4 0.7 1.1 1 0 0 1 1 1 1 Golgi complex component 7 (COG7) DUF1474 PF07342.6 EER23598.1 - 0.014 15.6 0.1 0.051 13.8 0.0 2.0 3 0 0 3 3 2 0 Protein of unknown function (DUF1474) Prominin PF05478.6 EER23598.1 - 0.018 12.5 1.4 0.48 7.9 0.3 2.1 2 0 0 2 2 2 0 Prominin Apolipoprotein PF01442.13 EER23598.1 - 0.023 14.1 7.5 0.034 13.6 5.2 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain BAR PF03114.13 EER23598.1 - 0.053 13.0 3.0 0.072 12.5 2.1 1.2 1 0 0 1 1 1 0 BAR domain TBCA PF02970.11 EER23598.1 - 0.66 10.0 7.5 0.92 9.6 0.8 3.0 2 1 2 4 4 4 0 Tubulin binding cofactor A DUF1664 PF07889.7 EER23598.1 - 0.71 9.6 5.1 0.81 9.4 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Histone_HNS PF00816.16 EER23598.1 - 2.1 8.9 6.6 0.21 12.1 1.3 1.8 2 0 0 2 2 2 0 H-NS histone family ZapA PF05164.8 EER23598.1 - 3.6 7.6 9.2 4.7 7.2 0.0 3.4 2 1 0 2 2 2 0 Cell division protein ZapA DUF501 PF04417.7 EER23598.1 - 3.6 7.4 5.3 0.87 9.4 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF501) Synaptobrevin PF00957.16 EER23598.1 - 4.7 6.8 7.2 0.78 9.3 1.2 2.6 3 1 1 4 4 4 0 Synaptobrevin Mnd1 PF03962.10 EER23598.1 - 6.8 6.3 9.6 0.84 9.2 0.7 2.1 1 1 1 2 2 2 0 Mnd1 family Cep57_CLD_2 PF14197.1 EER23598.1 - 7.7 6.5 11.8 7 6.6 5.7 2.6 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF2407_C PF13373.1 EER23599.1 - 1.1e-43 148.5 0.1 1.4e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EER23599.1 - 1.5e-30 105.2 0.0 2.5e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EER23599.1 - 0.002 17.5 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Fe-S_biosyn PF01521.15 EER23600.1 - 4.5e-22 78.0 0.0 7.7e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PROL5-SMR PF15621.1 EER23600.1 - 5.7 7.4 10.8 1.1 9.7 0.1 2.3 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF1741 PF08427.5 EER23601.1 - 2.2e-88 295.7 0.6 5.7e-88 294.3 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) DUF2636 PF11120.3 EER23601.1 - 0.042 13.3 0.2 18 4.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) MRG PF05712.8 EER23602.1 - 3.7e-54 182.5 0.1 6.7e-54 181.7 0.1 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EER23602.1 - 1.4e-07 31.0 3.3 1.4e-07 31.0 2.3 1.9 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EER23602.1 - 0.017 14.7 3.4 0.093 12.4 2.3 2.3 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.5 EER23603.1 - 2.4e-28 97.6 2.4 5.7e-28 96.3 1.0 2.0 2 0 0 2 2 2 1 Cnl2/NKP2 family protein DUF4446 PF14584.1 EER23603.1 - 0.011 15.5 0.2 0.92 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF972 PF06156.8 EER23603.1 - 0.026 14.8 2.1 1.9 8.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) KfrA_N PF11740.3 EER23603.1 - 0.039 14.3 1.0 0.2 12.1 0.1 2.0 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Prefoldin_2 PF01920.15 EER23603.1 - 0.041 13.6 6.8 0.48 10.2 0.1 2.7 2 1 0 2 2 2 0 Prefoldin subunit Mod_r PF07200.8 EER23603.1 - 0.65 9.8 4.9 5.8 6.8 3.1 2.4 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.6 EER23603.1 - 0.69 9.8 3.6 52 3.8 0.2 3.4 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Ctf8 PF09696.5 EER23605.1 - 5.2e-36 123.1 0.0 6.5e-36 122.7 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Glyoxalase PF00903.20 EER23606.1 - 2.2e-21 76.1 0.0 1.5e-16 60.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EER23606.1 - 6e-14 51.9 0.0 3.3e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EER23606.1 - 3.4e-10 40.4 0.0 1.8e-06 28.4 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EER23606.1 - 3.9e-06 26.8 0.0 0.002 18.0 0.0 3.1 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EER23606.1 - 2.1e-05 24.5 0.0 0.36 10.7 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain Imm21 PF15569.1 EER23606.1 - 0.098 12.4 0.1 5.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 21 RabGAP-TBC PF00566.13 EER23607.1 - 1.7e-51 174.7 0.4 2.7e-50 170.8 0.1 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF4200 PF13863.1 EER23607.1 - 0.0046 16.8 9.1 0.0046 16.8 6.3 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4200) SPAM PF02090.10 EER23607.1 - 0.038 13.9 7.5 0.084 12.8 5.2 1.6 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein DUF4252 PF14060.1 EER23607.1 - 0.16 11.4 3.3 0.095 12.2 0.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4252) ATG16 PF08614.6 EER23607.1 - 3.4 7.4 34.1 0.76 9.5 4.9 3.7 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 EER23607.1 - 7.9 6.3 23.0 0.066 13.1 2.6 3.2 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding PPTA PF01239.17 EER23608.1 - 1.5e-35 119.0 12.1 7e-08 31.4 0.1 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Trns_repr_metal PF02583.12 EER23608.1 - 0.054 13.6 0.2 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor WD40 PF00400.27 EER23609.1 - 1.1e-12 47.2 2.6 1.3e-06 28.0 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Utp12 PF04003.7 EER23610.1 - 4.2e-23 81.3 0.3 7.7e-23 80.5 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Daxx PF03344.10 EER23610.1 - 1.3 7.4 42.6 0.7 8.3 16.8 2.2 2 0 0 2 2 2 0 Daxx Family Bromodomain PF00439.20 EER23611.1 - 1.4e-43 146.6 1.1 8e-22 76.9 0.2 2.6 2 0 0 2 2 2 2 Bromodomain HAUS4 PF14735.1 EER23612.1 - 1.8e-08 34.0 3.4 3.3e-08 33.1 2.3 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 IncA PF04156.9 EER23612.1 - 0.16 11.5 2.8 2.9 7.4 1.3 2.6 2 1 0 2 2 2 0 IncA protein Ribosomal_S30 PF04758.9 EER23612.1 - 0.72 9.6 4.9 0.16 11.7 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein S30 zf-CSL PF05207.8 EER23613.1 - 6.3e-24 83.2 0.3 7.6e-24 82.9 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EER23613.1 - 0.1 12.5 0.2 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Frataxin_Cyay PF01491.11 EER23614.1 - 5.8e-32 109.7 0.0 7.9e-32 109.3 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Axin_b-cat_bind PF08833.5 EER23614.1 - 9.7 5.9 9.5 0.25 11.1 0.8 2.2 2 0 0 2 2 2 0 Axin beta-catenin binding domain AKAP7_NLS PF10469.4 EER23615.1 - 1.3e-17 64.2 0.0 2.2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain DUF1797 PF08796.5 EER23615.1 - 0.16 11.8 0.1 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1797) Sec6 PF06046.8 EER23616.1 - 1.2e-171 571.6 4.4 1.2e-171 571.6 3.0 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EER23616.1 - 0.22 10.2 8.4 0.14 10.8 0.8 2.6 3 0 0 3 3 3 0 Vps53-like, N-terminal DUF572 PF04502.8 EER23616.1 - 3.8 6.6 6.2 8.3 5.5 4.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L30 PF00327.15 EER23617.1 - 5.9e-15 54.5 0.3 7.4e-15 54.2 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.14 EER23618.1 - 5.4e-21 74.4 0.0 8.8e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EER23618.1 - 1.3e-05 24.0 0.0 0.00018 20.4 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EER23618.1 - 0.00069 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EER23618.1 - 0.049 12.5 0.0 0.078 11.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_1_2 PF00155.16 EER23619.1 - 1.3e-93 313.8 0.0 1.5e-93 313.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FAD_binding_3 PF01494.14 EER23620.1 - 1.9e-21 76.4 0.0 3.4e-21 75.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EER23620.1 - 4.5e-07 29.1 1.4 0.00065 18.7 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER23620.1 - 2.4e-05 24.2 0.1 6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EER23620.1 - 0.00022 20.2 0.8 0.00088 18.2 0.2 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EER23620.1 - 0.00087 18.3 0.7 0.0036 16.2 0.5 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EER23620.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EER23620.1 - 0.017 15.0 0.2 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER23620.1 - 0.024 14.7 0.3 0.039 14.0 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EER23620.1 - 0.031 13.8 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EER23620.1 - 0.085 11.3 0.1 0.15 10.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EER23620.1 - 0.14 10.9 2.5 0.7 8.6 1.8 1.9 1 1 0 1 1 1 0 Glucose inhibited division protein A Bromo_TP PF07524.8 EER23621.1 - 2.2e-08 33.7 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated BRO1 PF03097.13 EER23622.1 - 7.1e-05 21.7 0.0 0.00013 20.9 0.0 1.4 1 0 0 1 1 1 1 BRO1-like domain NDUFB10 PF10249.4 EER23623.1 - 0.0024 18.0 0.1 0.0043 17.2 0.1 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 Glyco_transf_34 PF05637.7 EER23624.1 - 8.1e-63 212.1 0.1 1.2e-62 211.5 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family PTR2 PF00854.16 EER23625.1 - 9.3e-53 179.3 12.2 2e-27 95.9 4.3 2.3 1 1 1 2 2 2 2 POT family MFS_1 PF07690.11 EER23625.1 - 3.5e-14 52.2 31.6 1.4e-10 40.4 14.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 EER23625.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF202) TFR_dimer PF04253.10 EER23626.1 - 4.1e-22 78.0 0.0 6.3e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EER23626.1 - 1.2e-16 60.9 0.0 2.2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EER23626.1 - 0.00095 18.8 0.1 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EER23626.1 - 0.044 13.2 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Pkinase PF00069.20 EER23627.1 - 2.1e-70 236.8 0.0 3.1e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23627.1 - 5.3e-35 120.7 0.0 8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EER23627.1 - 1.8e-10 40.7 0.2 8.7e-10 38.5 0.1 2.2 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EER23627.1 - 0.0051 15.8 0.0 0.011 14.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EER23627.1 - 0.0094 15.0 0.1 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER23627.1 - 0.026 14.2 0.0 5 6.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Lact-deh-memb PF09330.6 EER23627.1 - 0.036 13.4 0.1 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Beta_elim_lyase PF01212.16 EER23628.1 - 3.3e-61 206.9 0.0 4.3e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EER23628.1 - 0.0036 15.6 0.0 0.0059 14.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme RNase_T PF00929.19 EER23629.1 - 5.3e-25 88.6 0.0 7.9e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease MFS_1 PF07690.11 EER23630.1 - 1.6e-12 46.8 60.3 1.5e-10 40.3 41.1 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EER23630.1 - 2.7e-06 25.8 23.0 4.3e-06 25.2 15.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ARL6IP6 PF15062.1 EER23630.1 - 0.046 13.6 0.3 0.41 10.5 0.0 2.7 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix Acetyltransf_8 PF13523.1 EER23631.1 - 1.2e-43 148.5 1.4 1.9e-43 147.9 0.9 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EER23631.1 - 0.029 14.5 0.1 0.054 13.6 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 EER23632.1 - 6.4e-88 294.9 0.0 8.3e-88 294.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER23632.1 - 2.3e-14 54.0 0.0 4.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.1 EER23633.1 - 1.3e-119 399.1 0.0 1.5e-119 398.9 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EER23633.1 - 2.4e-14 53.8 0.0 1.3e-12 48.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER23633.1 - 1.6e-09 37.7 0.2 1.8e-06 27.8 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EER23633.1 - 9.9e-07 28.8 0.0 0.00021 21.2 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER23633.1 - 0.0024 18.2 0.0 0.21 12.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EER23633.1 - 0.011 14.6 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EER23633.1 - 0.021 14.9 0.0 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EER23633.1 - 0.043 12.6 0.1 7.3 5.3 0.1 2.2 1 1 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EER23633.1 - 0.07 13.1 0.5 0.22 11.5 0.1 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER23634.1 - 8.8e-08 32.2 0.0 3.3e-07 30.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER23634.1 - 2.9e-07 30.7 0.0 0.012 15.6 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER23634.1 - 3.2e-07 30.6 1.0 5.1e-06 26.7 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EER23634.1 - 0.00053 19.0 0.5 0.0024 16.8 0.0 2.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EER23634.1 - 0.0006 19.6 0.7 1.6 8.5 0.0 3.6 2 1 1 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 EER23634.1 - 0.0082 15.0 0.0 1.1 8.0 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EER23634.1 - 0.057 12.3 0.4 3.5 6.4 0.2 2.3 1 1 1 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EER23634.1 - 0.75 8.5 2.3 28 3.3 0.2 3.1 3 1 1 4 4 4 0 Glucose inhibited division protein A ABC_membrane PF00664.18 EER23635.1 - 1.2e-77 261.0 36.8 4.8e-41 140.9 8.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EER23635.1 - 1.3e-66 223.0 0.0 1.7e-32 112.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EER23635.1 - 9.2e-15 54.4 2.6 1.9e-05 23.9 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER23635.1 - 3.7e-11 43.5 0.1 0.011 15.6 0.1 4.4 4 0 0 4 4 4 3 AAA domain AAA_29 PF13555.1 EER23635.1 - 1.2e-08 34.2 0.4 0.0055 16.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EER23635.1 - 2.3e-08 34.8 0.0 0.0081 16.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EER23635.1 - 3.1e-07 29.7 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 EER23635.1 - 3.8e-07 30.2 2.9 0.019 14.9 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EER23635.1 - 4.7e-06 25.4 0.6 0.0026 16.4 0.0 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EER23635.1 - 5.4e-06 25.6 0.0 0.014 14.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EER23635.1 - 1.2e-05 25.3 0.0 0.63 10.1 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 EER23635.1 - 2.1e-05 24.0 0.1 0.23 10.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA PF00004.24 EER23635.1 - 6.4e-05 23.1 0.2 0.49 10.5 0.1 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 EER23635.1 - 9.4e-05 22.2 0.5 0.79 9.6 0.1 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.1 EER23635.1 - 0.00013 22.3 0.0 0.67 10.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EER23635.1 - 0.00013 21.8 0.0 0.49 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EER23635.1 - 0.00022 20.8 0.1 0.3 10.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EER23635.1 - 0.00052 20.3 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EER23635.1 - 0.00093 18.7 0.6 0.71 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 EER23635.1 - 0.0013 18.5 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 DUF3987 PF13148.1 EER23635.1 - 0.0016 17.0 0.0 0.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_14 PF13173.1 EER23635.1 - 0.0035 17.2 0.0 4 7.3 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EER23635.1 - 0.0089 15.7 0.0 1.8 8.2 0.0 3.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 EER23635.1 - 0.011 15.4 0.0 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 EER23635.1 - 0.011 15.3 0.1 1.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EER23635.1 - 0.025 14.5 0.1 7.1 6.6 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EER23635.1 - 0.037 14.2 0.0 35 4.6 0.0 3.5 3 0 0 3 3 3 0 RNA helicase Gtr1_RagA PF04670.7 EER23635.1 - 0.06 12.4 0.0 9.9 5.2 0.0 2.7 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EER23635.1 - 0.063 12.3 0.0 0.21 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ATP-synt_ab PF00006.20 EER23635.1 - 0.1 12.0 1.3 4.7 6.6 0.1 3.0 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EER23635.1 - 0.14 11.0 0.1 14 4.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AMP-binding PF00501.23 EER23636.1 - 1.4e-84 283.9 0.0 4.8e-82 275.5 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EER23636.1 - 1.2e-56 191.7 0.0 2.1e-35 122.0 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EER23636.1 - 2.3e-28 98.2 0.0 2.7e-13 49.9 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site OPT PF03169.10 EER23637.1 - 3.3e-181 603.9 48.0 3.8e-181 603.7 33.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glutaredoxin PF00462.19 EER23638.1 - 1e-18 67.0 0.0 4.3e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EER23638.1 - 1.9e-13 50.0 0.0 6.3e-13 48.3 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EER23638.1 - 0.00045 20.2 0.0 0.28 11.3 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like ArsC PF03960.10 EER23638.1 - 0.021 14.8 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 ArsC family TrbC_Ftype PF09673.5 EER23638.1 - 0.043 13.4 0.0 0.26 10.8 0.0 2.2 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein TauD PF02668.11 EER23639.1 - 2.7e-59 200.9 0.0 3.4e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family LigD_N PF13298.1 EER23639.1 - 0.009 16.1 0.1 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) CsiD PF08943.5 EER23639.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 CsiD Metal_hydrol PF10118.4 EER23639.1 - 0.14 11.5 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Predicted metal-dependent hydrolase Ank_2 PF12796.2 EER23640.1 - 9.6e-65 214.9 1.9 1.2e-09 38.3 0.0 7.6 3 2 5 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER23640.1 - 5.3e-51 170.1 7.5 7.7e-09 35.8 0.0 10.3 6 3 4 10 10 10 10 Ankyrin repeats (many copies) Ank PF00023.25 EER23640.1 - 1e-50 167.0 0.6 5.2e-06 26.0 0.0 13.0 12 1 0 12 12 12 9 Ankyrin repeat Ank_3 PF13606.1 EER23640.1 - 2.3e-43 141.8 0.6 0.0031 17.5 0.0 14.1 13 1 1 14 14 14 12 Ankyrin repeat Ank_5 PF13857.1 EER23640.1 - 1.6e-37 126.6 15.0 8.1e-07 29.0 0.0 12.4 9 2 5 14 14 14 11 Ankyrin repeats (many copies) F-box PF00646.28 EER23640.1 - 0.045 13.4 0.8 0.11 12.1 0.6 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EER23640.1 - 0.074 12.7 0.4 0.15 11.7 0.3 1.6 1 0 0 1 1 1 0 F-box-like Mito_carr PF00153.22 EER23641.1 - 8.8e-69 227.2 2.8 4.4e-24 84.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tubulin PF00091.20 EER23642.1 - 1.1e-65 221.4 0.0 1.6e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EER23642.1 - 3.1e-43 146.8 0.0 4.7e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EER23642.1 - 0.00049 19.6 0.0 0.0009 18.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain MS_channel PF00924.13 EER23643.1 - 5.6e-24 84.6 3.1 9.2e-24 83.9 2.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EER23643.1 - 0.0001 21.3 0.7 0.00023 20.2 0.5 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EER23643.1 - 0.00019 20.6 0.1 0.00049 19.3 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EER23643.1 - 0.00043 19.9 0.1 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EER23643.1 - 0.00059 19.9 0.4 0.0016 18.5 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EER23643.1 - 0.079 12.5 1.5 0.19 11.3 1.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair ABC2_membrane PF01061.19 EER23644.1 - 6.4e-94 312.9 59.7 4.7e-48 163.1 13.2 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EER23644.1 - 1.9e-37 127.0 0.1 5.9e-33 112.6 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EER23644.1 - 2.8e-37 128.0 0.0 2.2e-17 63.6 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EER23644.1 - 1.7e-21 76.0 0.1 1.7e-21 76.0 0.0 2.1 3 0 0 3 3 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EER23644.1 - 5.3e-08 32.5 0.0 0.00019 20.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EER23644.1 - 6e-05 22.9 0.0 0.017 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EER23644.1 - 7.1e-05 22.0 0.1 0.0051 16.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 EER23644.1 - 0.00024 20.2 53.9 0.0048 15.9 16.9 3.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_17 PF13207.1 EER23644.1 - 0.00043 21.0 0.0 0.15 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EER23644.1 - 0.00053 20.2 0.0 0.068 13.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EER23644.1 - 0.0014 18.1 1.5 0.048 13.1 0.2 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EER23644.1 - 0.0017 17.8 0.9 0.014 14.8 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EER23644.1 - 0.0052 16.9 0.1 1.8 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EER23644.1 - 0.011 15.7 0.4 0.18 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 EER23644.1 - 0.012 15.2 0.6 1.8 8.1 0.1 2.8 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.1 EER23644.1 - 0.017 14.8 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain SMC_N PF02463.14 EER23644.1 - 0.018 14.2 0.0 0.61 9.2 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER23644.1 - 0.052 13.5 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EER23644.1 - 0.076 12.4 0.1 0.73 9.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EER23644.1 - 0.12 11.8 0.0 5 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EER23644.1 - 0.13 11.8 0.4 5.3 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EER23644.1 - 0.13 12.7 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EER23644.1 - 0.15 12.0 0.0 0.89 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EER23644.1 - 0.17 11.3 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CRISPR_Cse1 PF09481.5 EER23644.1 - 0.19 10.4 1.6 0.38 9.4 0.2 1.9 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) UPF0079 PF02367.12 EER23644.1 - 0.29 10.7 1.4 5 6.7 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 zf-C2H2_4 PF13894.1 EER23645.1 - 0.014 15.7 15.7 0.89 10.0 0.2 4.3 3 1 0 3 3 3 0 C2H2-type zinc finger CYSTM PF12734.2 EER23646.1 - 2.2e-07 30.8 29.6 2.2e-07 30.8 20.5 5.2 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance XYPPX PF02162.12 EER23646.1 - 0.071 12.7 25.8 0.071 12.7 17.9 3.5 2 2 1 3 3 3 0 XYPPX repeat (two copies) Ribul_P_3_epim PF00834.14 EER23647.1 - 1.7e-65 219.9 0.0 3.3e-64 215.7 0.0 2.0 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 EER23647.1 - 0.021 14.2 0.1 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family ThiG PF05690.9 EER23647.1 - 0.026 13.5 0.5 0.038 13.0 0.4 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG PcrB PF01884.12 EER23647.1 - 0.12 11.5 0.7 0.26 10.4 0.5 1.5 1 1 0 1 1 1 0 PcrB family SH3BGR PF04908.10 EER23648.1 - 0.0033 17.3 0.0 0.011 15.7 0.0 1.9 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein zf-BED PF02892.10 EER23649.1 - 0.0028 17.3 2.9 0.71 9.6 0.1 2.6 2 0 0 2 2 2 2 BED zinc finger Methyltransf_11 PF08241.7 EER23650.1 - 1.4e-06 28.6 0.0 5.1e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER23650.1 - 0.051 13.2 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 EER23651.1 - 2.2e-15 55.9 1.4 3.1e-15 55.4 1.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EER23651.1 - 0.026 14.4 0.0 0.031 14.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DRMBL PF07522.9 EER23652.1 - 6.5e-35 119.4 0.0 1.3e-34 118.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EER23652.1 - 2.2e-12 46.9 0.0 3.9e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GST_N_3 PF13417.1 EER23653.1 - 1.3e-11 44.5 0.0 2.8e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EER23653.1 - 4.9e-07 29.6 0.0 8.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EER23653.1 - 4.6e-05 23.5 0.0 0.0011 19.0 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 EER23654.1 - 1.7e-28 99.3 51.9 9.2e-28 96.9 20.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CECR6_TMEM121 PF14997.1 EER23655.1 - 0.38 10.3 5.1 0.33 10.5 1.0 2.1 2 0 0 2 2 2 0 CECR6/TMEM121 family DUF4233 PF14017.1 EER23655.1 - 0.58 10.1 4.4 0.24 11.3 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) FAD_binding_4 PF01565.18 EER23656.1 - 1.5e-36 124.9 3.6 1.3e-35 121.8 2.3 2.4 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EER23656.1 - 6.6e-07 29.1 0.0 1.8e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EER23657.1 - 4.9e-64 216.5 0.0 6.3e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 EER23659.1 - 5.2e-100 335.6 0.0 1.2e-62 212.3 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EER23659.1 - 3.6e-06 26.7 0.1 0.00039 20.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold F-actin_cap_A PF01267.12 EER23660.1 - 3.7e-93 311.4 0.0 4.1e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Peptidase_M14 PF00246.19 EER23661.1 - 2.5e-75 253.6 0.1 3.2e-75 253.3 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EER23661.1 - 1.4e-10 40.6 0.1 6e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Peptidase_S8 PF00082.17 EER23662.1 - 3.3e-40 137.9 8.4 6e-40 137.1 5.9 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER23662.1 - 2.7e-19 69.4 0.0 5.9e-19 68.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase inhibitor I9 FSH1 PF03959.8 EER23664.1 - 2.3e-05 23.9 0.0 6.6e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) PP-binding PF00550.20 EER23665.1 - 0.013 15.7 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site PAP2 PF01569.16 EER23666.1 - 6.5e-21 74.3 1.1 6.5e-21 74.3 0.7 1.8 2 0 0 2 2 2 1 PAP2 superfamily Med7 PF05983.6 EER23667.1 - 4.2e-63 211.9 2.5 5.6e-63 211.5 1.7 1.2 1 0 0 1 1 1 1 MED7 protein Pox_F12L PF03337.8 EER23667.1 - 0.029 12.2 0.1 0.038 11.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein DUF607 PF04678.8 EER23667.1 - 0.15 12.0 1.4 0.23 11.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF607 V_ATPase_I PF01496.14 EER23667.1 - 0.24 9.2 1.4 0.3 8.8 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 EER23667.1 - 0.24 11.4 7.0 0.042 13.8 1.9 2.0 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin_2 PF01920.15 EER23667.1 - 0.34 10.7 8.3 0.075 12.8 2.8 2.0 2 0 0 2 2 2 0 Prefoldin subunit HEAT PF02985.17 EER23668.1 - 3.9e-20 70.0 3.0 9.1e-05 22.2 0.0 9.3 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 EER23668.1 - 4.7e-19 68.4 8.3 4.9e-06 26.7 0.0 8.9 5 3 3 9 9 9 5 HEAT repeats HEAT_EZ PF13513.1 EER23668.1 - 7.9e-17 61.2 10.4 7.1e-05 23.1 0.0 10.7 8 4 4 12 12 12 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EER23668.1 - 1.4e-10 41.3 0.1 0.18 12.2 0.0 6.7 6 2 1 7 7 7 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EER23668.1 - 2e-10 40.8 0.3 0.0042 16.9 0.3 5.4 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.14 EER23668.1 - 6.9e-09 35.5 3.1 2.8e-08 33.5 0.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain ParcG PF10274.4 EER23668.1 - 3.8e-07 30.1 0.9 0.0049 16.8 0.1 3.5 3 0 0 3 3 3 2 Parkin co-regulated protein CLASP_N PF12348.3 EER23668.1 - 2.2e-06 27.1 0.0 0.0067 15.8 0.0 3.4 2 1 2 4 4 4 2 CLASP N terminal MMS19_C PF12460.3 EER23668.1 - 5.7e-06 25.3 2.8 0.00043 19.1 0.0 3.5 3 1 0 3 3 3 1 RNAPII transcription regulator C-terminal UME PF08064.8 EER23668.1 - 0.00013 21.8 0.0 0.99 9.3 0.0 4.8 3 2 2 5 5 5 2 UME (NUC010) domain Patched PF02460.13 EER23669.1 - 8.3e-78 262.1 12.9 2.1e-52 178.1 0.1 2.1 2 0 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EER23669.1 - 1.8e-51 173.6 7.1 1.8e-51 173.6 4.9 3.0 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EER23669.1 - 1.1e-07 30.8 7.7 1.1e-07 30.8 5.4 3.3 3 0 0 3 3 3 1 MMPL family Folate_rec PF03024.9 EER23669.1 - 0.014 15.0 2.9 0.026 14.1 2.0 1.4 1 0 0 1 1 1 0 Folate receptor family DUF2433 PF10360.4 EER23670.1 - 9.4e-54 181.2 0.0 1.4e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EER23670.1 - 0.0016 18.2 0.0 0.0052 16.6 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EER23670.1 - 0.0092 15.3 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAP1 PF08601.5 EER23671.1 - 1.1e-73 248.9 12.6 1.1e-73 248.9 8.7 2.5 2 1 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 EER23671.1 - 1.4e-08 34.5 10.7 3.3e-08 33.3 7.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor Adeno_PIX PF03955.9 EER23671.1 - 0.024 15.1 1.1 0.024 15.1 0.7 2.7 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) XhlA PF10779.4 EER23671.1 - 0.033 14.0 0.4 0.1 12.5 0.3 1.8 1 0 0 1 1 1 0 Haemolysin XhlA IncA PF04156.9 EER23671.1 - 0.57 9.7 6.8 1.1 8.7 4.7 1.5 1 0 0 1 1 1 0 IncA protein Macoilin PF09726.4 EER23671.1 - 3 6.0 13.5 0.16 10.2 0.6 2.3 2 0 0 2 2 2 0 Transmembrane protein Herpes_LMP2 PF07415.6 EER23671.1 - 4 5.9 6.6 6.3 5.2 4.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein bZIP_2 PF07716.10 EER23671.1 - 5.3 6.9 24.2 0.087 12.6 10.2 2.8 2 1 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 EER23671.1 - 7.4 6.9 17.3 0.15 12.3 7.0 1.9 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF4537 PF15057.1 EER23672.1 - 0.0032 17.2 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 EER23672.1 - 0.0081 15.7 1.2 0.025 14.1 0.1 2.0 2 0 0 2 2 2 1 SGF29 tudor-like domain Med9 PF07544.8 EER23672.1 - 0.11 12.2 0.6 0.2 11.3 0.4 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Rad9_Rad53_bind PF08605.5 EER23672.1 - 0.12 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding Fis1_TPR_C PF14853.1 EER23672.1 - 0.17 11.7 0.2 0.29 11.0 0.1 1.3 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat AATF-Che1 PF13339.1 EER23673.1 - 4.9e-35 120.5 0.5 4.9e-35 120.5 0.4 2.7 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EER23673.1 - 4.2e-33 113.2 0.1 1.1e-32 111.9 0.0 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Daxx PF03344.10 EER23673.1 - 5.7 5.3 26.1 0.0024 16.4 8.7 1.9 1 1 1 2 2 2 0 Daxx Family ParA PF10609.4 EER23674.1 - 3.4e-32 110.1 0.0 8.4e-32 108.8 0.0 1.7 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EER23674.1 - 4.9e-12 45.6 0.3 6.9e-08 32.1 0.0 2.3 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EER23674.1 - 6.9e-05 22.8 0.8 0.38 10.6 0.2 3.0 3 0 0 3 3 3 2 AAA domain Abhydrolase_3 PF07859.8 EER23675.1 - 1.1e-27 97.0 0.0 4.2e-18 65.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EER23675.1 - 1.4e-10 40.3 0.0 4.2e-10 38.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) WGG PF10273.4 EER23676.1 - 5.9e-31 106.3 0.2 9.4e-31 105.7 0.1 1.3 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF1626 PF07788.6 EER23676.1 - 0.0068 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1626) RRP7 PF12923.2 EER23676.1 - 0.27 11.2 0.1 0.27 11.2 0.1 1.8 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Packaging_FI PF14000.1 EER23676.1 - 3.7 7.7 9.4 15 5.7 6.5 1.8 1 1 0 1 1 1 0 DNA packaging protein FI GTP_EFTU PF00009.22 EER23677.1 - 3e-43 147.4 0.0 5.3e-43 146.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EER23677.1 - 9.2e-20 70.6 0.0 2e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EER23677.1 - 4e-09 36.4 0.2 1e-08 35.1 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EER23677.1 - 0.002 18.0 0.0 0.0047 16.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase CDC27 PF09507.5 EER23677.1 - 0.22 10.7 22.7 0.32 10.1 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ran-binding PF05508.6 EER23678.1 - 7.7e-109 363.2 0.6 9.9e-109 362.8 0.4 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BSD PF03909.12 EER23679.1 - 7e-17 60.9 1.1 1.3e-16 60.0 0.7 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 EER23679.1 - 0.028 14.1 2.3 0.047 13.4 1.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EER23679.1 - 1.3 9.1 3.7 2.2 8.4 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Lyase_1 PF00206.15 EER23681.1 - 1.4e-88 297.1 0.0 1.9e-88 296.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EER23681.1 - 3.6e-26 91.0 0.0 8.8e-26 89.7 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1216 PF06746.6 EER23681.1 - 0.027 14.2 0.0 4.3 7.1 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1216) DUF3052 PF11253.3 EER23681.1 - 0.069 12.7 0.1 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3052) DUF1451 PF07295.6 EER23681.1 - 0.11 12.3 0.3 0.45 10.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1451) Rad4 PF03835.10 EER23682.1 - 3.1e-35 120.6 0.0 7.3e-35 119.4 0.0 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EER23682.1 - 1.3e-25 88.8 0.0 3e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EER23682.1 - 1.1e-21 76.0 0.0 2.4e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EER23682.1 - 1e-15 57.7 0.0 2.6e-15 56.4 0.0 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EER23682.1 - 5.2e-05 23.4 0.0 0.00029 21.0 0.0 2.3 1 1 0 1 1 1 1 Transglutaminase-like superfamily Tropomyosin_1 PF12718.2 EER23683.1 - 0.0078 16.0 24.5 0.0078 16.0 17.0 10.2 2 2 7 9 9 9 5 Tropomyosin like Filament PF00038.16 EER23683.1 - 0.013 15.0 152.2 0.0087 15.5 7.7 7.6 1 1 6 7 7 7 0 Intermediate filament protein PTPA PF03095.10 EER23685.1 - 1.6e-113 378.8 0.0 1.9e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ribosomal_S7 PF00177.16 EER23685.1 - 0.04 13.4 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e DUF572 PF04502.8 EER23686.1 - 4.2e-46 157.6 2.0 5.1e-46 157.3 1.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) Glyco_hydro_3 PF00933.16 EER23687.1 - 1.5e-93 313.1 0.0 2e-93 312.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EER23687.1 - 1.6e-60 204.5 0.1 2.5e-59 200.5 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EER23687.1 - 7.3e-18 64.2 0.1 1.3e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PNP_UDP_1 PF01048.15 EER23689.1 - 1.2e-36 125.8 0.1 1.5e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily BUD22 PF09073.5 EER23690.1 - 6.9e-91 305.4 13.7 9.1e-91 305.0 9.5 1.2 1 0 0 1 1 1 1 BUD22 COPI_C PF06957.6 EER23690.1 - 0.39 9.1 4.6 0.3 9.5 0.4 2.1 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus Complex1_30kDa PF00329.14 EER23692.1 - 1.3e-35 121.7 0.1 1.9e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 EER23693.1 - 6.7e-19 67.2 13.4 1.1e-18 66.4 9.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EER23693.1 - 8.3e-06 25.3 0.0 1.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EER23693.1 - 0.00014 21.4 7.6 0.00025 20.6 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EER23693.1 - 0.0013 18.0 2.1 0.0013 18.0 1.5 3.4 4 1 0 4 4 4 1 Rtf2 RING-finger Baculo_IE-1 PF05290.6 EER23693.1 - 0.0027 17.4 4.4 0.0053 16.4 3.0 1.4 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 EER23693.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EER23693.1 - 0.19 11.4 12.7 0.38 10.4 8.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER23693.1 - 1.2 9.2 11.9 2.4 8.2 8.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) E1_dh PF00676.15 EER23694.1 - 1e-88 296.9 0.3 1.2e-88 296.6 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EER23694.1 - 2.8e-05 23.7 0.1 0.0003 20.4 0.1 2.3 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.5 EER23694.1 - 0.0032 16.0 0.0 0.0056 15.2 0.0 1.4 1 0 0 1 1 1 1 XFP N-terminal domain DXP_synthase_N PF13292.1 EER23694.1 - 0.023 13.6 0.0 0.13 11.1 0.0 1.9 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase GAT PF03127.9 EER23694.1 - 0.1 12.6 0.3 0.2 11.6 0.2 1.4 1 0 0 1 1 1 0 GAT domain Ubie_methyltran PF01209.13 EER23695.1 - 1.5e-79 266.3 0.0 1.9e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EER23695.1 - 5.3e-14 52.0 0.0 8e-14 51.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23695.1 - 2.6e-13 50.2 0.0 9.2e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER23695.1 - 8.1e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER23695.1 - 2.9e-09 37.1 0.0 1.3e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER23695.1 - 4.5e-09 36.6 0.0 7.3e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER23695.1 - 1.2e-07 32.3 0.0 2.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER23695.1 - 0.00019 21.4 0.0 0.00049 20.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EER23695.1 - 0.023 14.3 0.0 0.14 11.8 0.0 2.1 2 1 0 3 3 3 0 Hypothetical methyltransferase Cytomega_TRL10 PF06084.6 EER23696.1 - 0.088 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein SIS PF01380.17 EER23697.1 - 2.5e-09 36.8 0.0 5.6e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EER23697.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 SIS domain BTB PF00651.26 EER23698.1 - 0.00012 22.0 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RVT_1 PF00078.22 EER23699.1 - 7.2e-06 25.5 0.0 1.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HAD PF12710.2 EER23700.1 - 7.1e-11 42.6 0.0 1.1e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EER23700.1 - 0.00046 20.4 0.0 0.0013 18.9 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EER23700.1 - 0.0016 17.6 0.0 0.72 8.9 0.0 2.2 2 0 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.7 EER23700.1 - 0.0046 16.3 0.0 0.016 14.5 0.0 1.9 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) CTP_transf_2 PF01467.21 EER23701.1 - 3.9e-25 88.7 0.0 5e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase HECT PF00632.20 EER23702.1 - 2.2e-81 273.4 0.0 5.4e-81 272.1 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 EER23702.1 - 0.011 15.7 0.8 0.67 10.1 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat OAD_beta PF03977.8 EER23702.1 - 0.27 9.9 0.0 0.45 9.2 0.0 1.2 1 0 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Arm PF00514.18 EER23702.1 - 1 9.2 8.3 11 5.9 0.1 5.7 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat eIF3_subunit PF08597.5 EER23703.1 - 0.00077 19.1 0.5 0.00077 19.1 0.3 2.0 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit Gpi16 PF04113.9 EER23704.1 - 1.3e-237 789.4 0.0 1.6e-237 789.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 EER23705.1 - 1.3e-72 244.4 0.2 1.6e-72 244.1 0.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus AAA_13 PF13166.1 EER23705.1 - 0.031 12.7 1.0 0.045 12.2 0.7 1.3 1 0 0 1 1 1 0 AAA domain TelA PF05816.6 EER23705.1 - 0.14 10.7 1.7 0.13 10.9 0.3 1.5 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) GRP PF07172.6 EER23705.1 - 0.41 11.1 23.0 0.38 11.2 14.8 1.8 2 0 0 2 2 2 0 Glycine rich protein family TFIIS_M PF07500.9 EER23706.1 - 3.7e-23 81.7 0.0 6.8e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EER23706.1 - 9.6e-18 64.7 0.0 2e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EER23706.1 - 2.1e-10 40.1 12.5 3.7e-10 39.3 8.7 1.4 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 EER23706.1 - 0.017 15.3 0.7 0.07 13.3 0.5 2.1 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 EER23706.1 - 0.057 12.7 5.8 0.093 12.0 4.0 1.4 1 0 0 1 1 1 0 PHD-finger Terminase_GpA PF05876.7 EER23706.1 - 0.15 10.4 7.3 0.23 9.7 5.1 1.2 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Fzo_mitofusin PF04799.8 EER23707.1 - 1 8.7 4.9 0.33 10.3 1.1 1.7 2 0 0 2 2 2 0 fzo-like conserved region Adeno_PIX PF03955.9 EER23707.1 - 3.1 8.3 5.6 0.45 11.0 0.4 2.1 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) HAUS6_N PF14661.1 EER23707.1 - 4.2 6.6 8.9 0.52 9.6 1.6 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF4375 PF14300.1 EER23707.1 - 5.3 7.0 7.1 1.5 8.8 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) FF PF01846.14 EER23708.1 - 1.1e-14 54.0 10.0 2.5e-10 40.1 0.1 3.6 3 0 0 3 3 3 3 FF domain WW PF00397.21 EER23708.1 - 2.5e-08 33.6 1.0 2.5e-08 33.6 0.7 2.6 3 0 0 3 3 3 1 WW domain Proteasome PF00227.21 EER23709.1 - 3.7e-61 205.7 0.2 4.5e-61 205.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EER23709.1 - 3.6e-14 51.7 0.2 6.9e-14 50.8 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 EER23709.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit TMF_TATA_bd PF12325.3 EER23710.1 - 0.0065 16.1 1.9 0.5 10.1 0.4 2.1 1 1 1 2 2 2 2 TATA element modulatory factor 1 TATA binding Aida_N PF08910.5 EER23710.1 - 0.053 13.7 0.5 0.13 12.5 0.3 1.7 1 1 0 1 1 1 0 Aida N-terminus Rpr2 PF04032.11 EER23710.1 - 0.11 12.3 0.7 0.24 11.3 0.5 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain STAG PF08514.6 EER23710.1 - 0.12 12.0 0.5 4 7.1 0.1 2.0 2 0 0 2 2 2 0 STAG domain DUF641 PF04859.7 EER23710.1 - 0.14 11.9 1.3 0.2 11.3 0.9 1.3 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EER23710.1 - 0.9 9.0 3.4 5.8 6.4 0.8 2.1 1 1 1 2 2 2 0 Septum formation initiator NAD_binding_10 PF13460.1 EER23712.1 - 1.1e-08 35.3 0.0 8.1e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EER23712.1 - 3.6e-05 23.1 0.0 0.00011 21.5 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EER23712.1 - 5.3e-05 23.5 0.1 0.00089 19.5 0.1 2.3 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.5 EER23712.1 - 0.035 12.5 0.0 0.057 11.8 0.0 1.3 1 0 0 1 1 1 0 HIM1 adh_short PF00106.20 EER23712.1 - 0.042 13.7 0.0 1.2 9.0 0.0 2.4 3 0 0 3 3 3 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EER23712.1 - 0.048 12.5 0.0 0.79 8.5 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein Epimerase PF01370.16 EER23712.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1471 PF07338.8 EER23712.1 - 0.074 12.6 0.3 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) 3Beta_HSD PF01073.14 EER23712.1 - 0.17 10.5 0.0 0.24 10.0 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family FAD_binding_1 PF00667.15 EER23713.1 - 1.3e-64 217.6 0.0 2e-64 217.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EER23713.1 - 9.3e-12 45.4 0.0 2.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EER23713.1 - 9.5e-11 41.8 0.0 2.3e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase FAD_binding_6 PF00970.19 EER23713.1 - 0.034 14.2 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain POR_N PF01855.14 EER23713.1 - 0.089 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Transketolase_C PF02780.15 EER23713.1 - 0.11 12.4 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Transketolase, C-terminal domain FtsJ PF01728.14 EER23714.1 - 7.7e-63 211.7 0.0 1e-62 211.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 EER23715.1 - 5e-41 139.9 0.0 1.1e-40 138.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER23715.1 - 2.1e-20 72.3 0.0 5.4e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EER23715.1 - 3.4e-05 22.4 0.0 0.0044 15.4 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF1253) SNF2_N PF00176.18 EER23715.1 - 0.00027 19.8 0.0 0.00041 19.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EER23715.1 - 0.042 13.6 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EER23715.1 - 0.059 13.5 2.0 0.13 12.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain Pyr_redox_3 PF13738.1 EER23716.1 - 8.6e-25 87.9 0.1 3.6e-23 82.6 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER23716.1 - 4.4e-14 51.5 0.2 5.3e-10 38.1 0.0 2.9 2 1 0 3 3 3 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EER23716.1 - 2.1e-07 30.1 0.0 0.0001 21.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EER23716.1 - 1.4e-06 28.2 0.0 5.1e-06 26.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER23716.1 - 1.2e-05 25.2 0.0 0.00057 19.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER23716.1 - 0.00099 18.9 0.1 1.1 8.9 0.0 3.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EER23716.1 - 0.0038 16.1 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EER23716.1 - 0.011 15.8 0.0 1.4 8.9 0.0 2.9 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EER23716.1 - 0.035 12.9 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EER23716.1 - 0.035 13.1 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EER23716.1 - 0.039 12.4 0.0 0.6 8.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.13 EER23717.1 - 2.7e-23 82.1 0.0 4.7e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain VHS PF00790.14 EER23718.1 - 2.9e-26 91.7 0.0 7.6e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EER23718.1 - 5.4e-11 42.3 0.8 1.3e-10 41.1 0.5 1.6 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 EER23718.1 - 0.00011 22.0 0.0 0.00071 19.4 0.0 2.1 2 0 0 2 2 2 1 ENTH domain Inositol_P PF00459.20 EER23719.1 - 5e-55 186.7 0.3 8.6e-55 185.9 0.2 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L6 PF00347.18 EER23720.1 - 1.7e-22 79.6 0.0 1.1e-12 48.3 0.0 2.6 3 0 0 3 3 3 2 Ribosomal protein L6 Tht1 PF04163.7 EER23721.1 - 2.5e-07 29.5 3.0 2.2e-06 26.3 2.1 2.1 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein DUF479 PF04336.7 EER23721.1 - 0.026 14.6 1.8 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF479 Pept_tRNA_hydro PF01195.14 EER23722.1 - 4.9e-26 91.3 0.0 1.1e-09 38.0 0.0 3.0 3 0 0 3 3 3 3 Peptidyl-tRNA hydrolase Aminotran_1_2 PF00155.16 EER23723.1 - 2.8e-37 128.5 0.0 3.2e-37 128.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.14 EER23723.1 - 0.0002 19.8 0.0 0.00029 19.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EER23723.1 - 0.0019 17.0 0.0 0.096 11.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_3 PF00202.16 EER23723.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 EER23723.1 - 0.037 12.2 0.0 0.052 11.8 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 EER23724.1 - 3.2e-39 134.7 0.0 1.4e-21 76.7 0.0 2.8 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EER23724.1 - 2.3e-35 122.0 0.0 5e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain BATS PF06968.8 EER23725.1 - 1.6e-26 91.9 0.0 6e-26 90.1 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EER23725.1 - 1.3e-16 61.2 0.0 2.7e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily DUF4630 PF15443.1 EER23725.1 - 0.07 12.9 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) Oxidored_FMN PF00724.15 EER23726.1 - 1e-66 225.2 0.0 1.3e-66 224.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EER23726.1 - 0.0051 15.6 0.1 0.01 14.6 0.0 1.5 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) XH PF03469.9 EER23726.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 XH domain GST_N_3 PF13417.1 EER23727.1 - 2.8e-10 40.2 0.0 4.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EER23727.1 - 4.9e-10 39.2 0.1 2e-09 37.2 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EER23727.1 - 7.6e-07 29.0 0.0 1.5e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EER23727.1 - 7.1e-05 22.9 0.0 0.00018 21.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER23727.1 - 0.00018 21.3 0.1 0.0003 20.6 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EER23727.1 - 0.0014 19.1 0.1 0.0049 17.3 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.13 EER23728.1 - 6.7e-47 159.7 0.0 9.4e-47 159.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EER23728.1 - 1.6e-25 89.1 0.0 3.1e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal HgmA PF04209.8 EER23729.1 - 4e-189 628.3 0.0 4.6e-189 628.1 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase TPR_11 PF13414.1 EER23730.1 - 0.00012 21.6 0.8 0.0047 16.5 0.3 2.3 2 0 0 2 2 2 2 TPR repeat Glyoxalase PF00903.20 EER23731.1 - 3.3e-21 75.6 0.6 3.2e-16 59.4 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EER23731.1 - 8.5e-13 48.2 0.5 2e-05 24.5 0.3 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EER23731.1 - 8e-10 39.2 0.1 0.00041 20.9 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EER23731.1 - 6.7e-06 26.0 0.3 0.00018 21.4 0.1 2.7 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EER23731.1 - 2.1e-05 24.5 0.1 0.034 14.0 0.2 2.8 2 1 0 2 2 2 2 Glyoxalase-like domain COX15-CtaA PF02628.10 EER23732.1 - 1.4e-97 326.1 6.6 1.7e-97 325.9 4.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PQ-loop PF04193.9 EER23732.1 - 0.13 11.7 3.1 4.2 7.0 0.0 3.0 3 0 0 3 3 3 0 PQ loop repeat Prok-RING_2 PF14445.1 EER23733.1 - 0.034 14.0 7.6 0.085 12.8 5.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-RanBP PF00641.13 EER23733.1 - 0.035 13.2 3.1 0.068 12.2 2.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-UDP PF14569.1 EER23733.1 - 0.053 13.2 0.6 0.18 11.5 0.4 1.9 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-B_box PF00643.19 EER23733.1 - 0.064 13.1 3.4 0.13 12.2 2.3 1.5 1 0 0 1 1 1 0 B-box zinc finger zf-RING_4 PF14570.1 EER23733.1 - 0.24 11.0 4.7 0.49 10.0 3.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain tRNA-synt_2 PF00152.15 EER23734.1 - 7.9e-92 307.5 0.3 1.3e-91 306.8 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EER23734.1 - 9.8e-12 44.5 0.0 5.4e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EER23734.1 - 5.1e-06 25.8 0.0 0.0048 16.1 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EER23734.1 - 0.0068 16.0 0.1 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) UCR_Fe-S_N PF10399.4 EER23734.1 - 0.074 12.2 2.4 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Dynamin_N PF00350.18 EER23735.1 - 1.7e-27 96.3 0.1 1.3e-26 93.4 0.0 2.6 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EER23735.1 - 9e-18 64.0 0.0 1.1e-15 57.2 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EER23735.1 - 0.00085 19.2 0.1 0.014 15.3 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER23735.1 - 0.0013 19.2 0.0 0.0071 16.8 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein GED PF02212.13 EER23735.1 - 0.0015 18.4 0.2 0.0047 16.7 0.1 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain IIGP PF05049.8 EER23735.1 - 0.076 11.8 0.1 3.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MobB PF03205.9 EER23735.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Surfac_D-trimer PF09006.6 EER23735.1 - 0.15 11.8 0.1 0.45 10.2 0.0 1.8 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation NTP_transferase PF00483.18 EER23736.1 - 1.5e-28 99.7 0.0 2.1e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EER23736.1 - 4.9e-08 32.1 7.2 1.5e-05 24.2 0.0 3.8 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EER23736.1 - 1.1e-07 32.0 0.0 1.7e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EER23736.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Bys1 PF04681.7 EER23737.1 - 7.6e-18 64.7 0.1 9.1e-18 64.4 0.1 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Amidohydro_2 PF04909.9 EER23739.1 - 5.5e-42 144.1 0.0 8.9e-42 143.5 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Dioxygenase_C PF00775.16 EER23740.1 - 2.1e-51 173.8 0.0 2.7e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EER23740.1 - 2e-13 50.0 0.0 3.2e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EER23740.1 - 1.1e-06 28.6 0.0 2.8e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EER23740.1 - 0.0056 16.7 0.1 0.022 14.7 0.0 2.0 2 1 0 2 2 2 1 Domain of unknown function (DUF4480) MFS_1 PF07690.11 EER23741.1 - 6.3e-33 113.9 36.3 8.9e-33 113.4 25.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EER23742.1 - 4e-35 121.7 0.0 4.6e-35 121.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER23742.1 - 7.2e-23 80.9 0.2 3.5e-22 78.7 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER23742.1 - 1.6e-18 67.1 0.0 5.3e-12 45.8 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Thioesterase PF00975.15 EER23742.1 - 2.4e-06 27.9 0.0 9.6e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 EER23742.1 - 2.7e-06 27.1 0.5 5.9e-06 26.0 0.3 1.7 1 1 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 EER23742.1 - 7.3e-05 22.1 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 EER23742.1 - 0.00014 20.8 0.4 0.00035 19.5 0.3 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EER23742.1 - 0.00021 21.0 0.0 0.00046 19.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ser_hydrolase PF06821.8 EER23742.1 - 0.00027 20.5 0.0 0.001 18.6 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.11 EER23742.1 - 0.00054 19.4 0.2 5.5 6.3 0.1 3.1 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_8 PF06259.7 EER23742.1 - 0.0035 16.8 0.3 0.0069 15.9 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_3 PF07859.8 EER23742.1 - 0.0041 16.7 0.1 0.0058 16.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EER23742.1 - 0.0048 16.6 0.0 0.02 14.6 0.0 1.8 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF1057 PF06342.7 EER23742.1 - 0.0054 15.5 0.0 0.0068 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase PF07224.6 EER23742.1 - 0.011 14.5 0.3 0.018 13.8 0.2 1.3 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.20 EER23742.1 - 0.012 15.1 0.1 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_4 PF08386.5 EER23742.1 - 0.026 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Peptidase_S9 PF00326.16 EER23742.1 - 0.027 13.6 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 EER23742.1 - 0.046 13.1 0.0 0.9 8.9 0.0 2.6 2 1 0 2 2 2 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.8 EER23742.1 - 0.073 11.3 3.1 1.4 7.1 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 EER23742.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.7 EER23742.1 - 0.14 10.6 0.1 2.8 6.3 0.3 2.5 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 EER23743.1 - 1.8e-25 89.3 0.1 2.9e-25 88.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER23743.1 - 5.7e-08 32.5 6.5 9.6e-08 31.8 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.12 EER23744.1 - 4.5e-33 114.1 0.0 1.8e-32 112.1 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III Pyridox_oxidase PF01243.15 EER23745.1 - 3.3e-08 33.4 0.0 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EER23745.1 - 8e-07 29.1 0.0 3.4e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EER23745.1 - 0.00059 20.3 0.0 0.0018 18.8 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-RING_2 PF13639.1 EER23746.1 - 5.8e-06 26.0 1.9 8.9e-06 25.4 0.2 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EER23746.1 - 0.0014 18.6 0.3 0.0026 17.8 0.0 1.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EER23746.1 - 0.16 11.8 0.3 0.32 10.8 0.0 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Atx10homo_assoc PF09759.4 EER23747.1 - 2.9e-30 103.9 1.2 4.7e-30 103.3 0.1 1.9 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain DUF3028 PF11229.3 EER23747.1 - 0.12 10.6 0.0 0.19 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) zf-DHHC PF01529.15 EER23748.1 - 0.029 13.7 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Rap1_C PF11626.3 EER23749.1 - 2.6e-24 84.8 0.1 6.6e-23 80.4 0.0 2.6 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EER23749.1 - 6.1e-21 73.9 0.5 6.9e-20 70.6 0.1 2.4 2 0 0 2 2 2 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EER23749.1 - 1.5e-11 44.7 4.9 7.2e-07 29.7 0.1 3.0 2 1 0 3 3 3 2 Rap1, DNA-binding Inhibitor_I68 PF10468.4 EER23749.1 - 0.07 13.3 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase inhibitor I68 LUC7 PF03194.10 EER23749.1 - 0.098 12.1 0.6 0.19 11.2 0.4 1.4 1 0 0 1 1 1 0 LUC7 N_terminus YtzH PF14165.1 EER23749.1 - 1.4 9.1 5.1 0.54 10.5 1.2 2.0 2 0 0 2 2 2 0 YtzH-like protein DUF4404 PF14357.1 EER23749.1 - 2.1 8.7 8.1 0.89 10.0 1.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Chromo PF00385.19 EER23750.1 - 1.5e-13 50.1 0.1 7.6e-13 47.9 0.0 2.2 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EER23750.1 - 1.2e-11 44.2 0.2 4.6e-09 35.9 0.1 2.4 2 0 0 2 2 2 2 Chromo shadow domain Cpn60_TCP1 PF00118.19 EER23751.1 - 1.1e-146 489.2 1.3 1.3e-146 489.1 0.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Resolvase PF00239.16 EER23751.1 - 0.049 13.5 0.3 0.54 10.1 0.1 2.3 2 0 0 2 2 2 0 Resolvase, N terminal domain Ank_2 PF12796.2 EER23752.1 - 2.5e-50 168.7 4.7 3.3e-15 56.1 0.0 8.5 6 3 0 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EER23752.1 - 1.4e-32 109.8 4.1 6.2e-06 25.7 0.0 10.9 10 1 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.1 EER23752.1 - 8.8e-31 105.2 2.9 0.0033 17.6 0.0 10.8 9 1 2 11 11 11 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 EER23752.1 - 5.9e-29 99.9 3.9 2.9e-05 24.4 0.0 12.1 11 2 2 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER23752.1 - 1.2e-27 93.1 2.7 0.0017 18.4 0.0 11.0 11 0 0 11 11 11 7 Ankyrin repeat YfkD PF14167.1 EER23752.1 - 0.031 13.3 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 YfkD-like protein Phage_T7_Capsid PF05396.6 EER23752.1 - 0.041 14.0 3.9 0.39 10.8 0.1 3.8 4 1 2 6 6 6 0 Phage T7 capsid assembly protein DUF3295 PF11702.3 EER23753.1 - 3.8e-152 507.8 38.2 4.3e-152 507.6 26.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EER23753.1 - 3.2e-12 45.7 3.0 6.3e-12 44.8 2.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Pyr_redox_3 PF13738.1 EER23754.1 - 0.00026 21.1 0.0 0.00063 19.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EER23754.1 - 0.006 16.6 0.3 0.16 12.0 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 EER23754.1 - 0.077 11.1 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like zf-C3HC PF07967.8 EER23755.1 - 2e-39 134.4 0.3 2.4e-36 124.4 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EER23755.1 - 5.1e-31 106.3 0.8 1.6e-28 98.3 0.0 2.7 3 0 0 3 3 3 2 Rsm1-like Pox_MCEL PF03291.11 EER23756.1 - 1.3e-50 172.2 0.0 3.1e-39 134.7 0.0 3.7 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EER23756.1 - 8.6e-09 35.7 0.0 4e-08 33.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23756.1 - 7.7e-08 32.7 0.0 0.0089 16.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EER23756.1 - 2.5e-07 31.2 0.0 5.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER23756.1 - 1.1e-05 25.0 0.0 0.00067 19.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER23756.1 - 1.5e-05 25.2 0.0 3.7e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER23756.1 - 3.3e-05 23.6 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EER23756.1 - 0.0018 17.3 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Sulfate_transp PF00916.15 EER23757.1 - 1.1e-77 260.7 7.9 1.1e-77 260.7 5.5 1.7 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EER23757.1 - 9.9e-29 98.8 4.1 9.9e-29 98.8 2.8 3.5 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EER23757.1 - 3.5e-08 32.8 0.0 6.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain zf-Nse PF11789.3 EER23758.1 - 5.1e-22 77.1 1.1 9.3e-22 76.3 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 EER23758.1 - 0.00019 21.1 0.5 0.00033 20.4 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EER23758.1 - 0.00049 19.7 0.7 0.0014 18.3 0.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.15 EER23758.1 - 0.011 15.2 1.5 0.15 11.5 0.1 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4 PF00097.20 EER23758.1 - 0.13 11.8 0.9 0.55 9.9 0.7 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.13 EER23759.1 - 3.1e-10 39.7 10.2 4.5e-10 39.2 7.1 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 EER23760.1 - 1e-21 75.8 2.9 1e-21 75.8 2.0 2.7 2 1 1 3 3 3 1 Copper fist DNA binding domain PEX11 PF05648.9 EER23761.1 - 7.2e-69 231.4 1.0 8.7e-69 231.1 0.7 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Sugar_tr PF00083.19 EER23762.1 - 4.6e-32 111.1 28.7 4.3e-21 75.0 5.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EER23762.1 - 4.4e-15 55.2 37.9 4.4e-15 55.2 26.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Dermcidin PF15291.1 EER23762.1 - 0.059 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Dermcidin, antibiotic peptide RPN7 PF10602.4 EER23763.1 - 8.5e-56 188.1 0.2 1.3e-55 187.4 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EER23763.1 - 2.3e-12 47.1 0.0 4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 EER23763.1 - 0.03 14.1 1.4 0.092 12.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3901 PF13040.1 EER23763.1 - 0.24 10.7 1.3 1.2 8.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3901) Aminotran_1_2 PF00155.16 EER23764.1 - 1.1e-38 133.2 0.0 1.5e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PEPCK_ATP PF01293.15 EER23765.1 - 7.4e-217 720.4 0.0 9e-217 720.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EER23765.1 - 0.036 14.3 0.0 8.9 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EER23765.1 - 0.05 13.1 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EER23765.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EER23765.1 - 0.074 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.22 EER23766.1 - 6.7e-58 192.4 2.0 1.2e-20 73.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Alpha_GJ PF03229.8 EER23766.1 - 8.7 6.7 10.9 0.92 9.8 1.8 2.4 2 1 0 2 2 2 0 Alphavirus glycoprotein J Meiotic_rec114 PF03525.9 EER23767.1 - 4.2e-05 22.2 2.3 0.0033 15.9 0.0 2.6 2 1 0 2 2 2 2 Meiotic recombination protein rec114 DUF2922 PF11148.3 EER23767.1 - 0.11 12.1 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) GPI-anchored PF10342.4 EER23769.1 - 6.4e-17 61.8 1.0 6.4e-17 61.8 0.7 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CARDB PF07705.6 EER23769.1 - 0.0099 15.9 1.7 0.25 11.4 0.8 2.3 1 1 1 2 2 2 1 CARDB DUF1771 PF08590.5 EER23770.1 - 8e-09 35.3 5.6 8e-09 35.3 3.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EER23770.1 - 3.4e-08 33.5 0.2 1.1e-07 31.9 0.1 2.0 2 0 0 2 2 2 1 Smr domain CUE PF02845.11 EER23770.1 - 1.1e-05 24.8 0.0 2.3e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 CUE domain SelR PF01641.13 EER23771.1 - 3.5e-51 172.1 0.2 4e-51 171.8 0.1 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 EER23771.1 - 0.0018 18.0 2.2 0.37 10.6 0.1 2.4 2 1 0 2 2 2 2 Double zinc ribbon GFA PF04828.9 EER23771.1 - 0.02 14.8 1.0 1.6 8.6 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.9 EER23771.1 - 0.028 14.4 1.1 0.27 11.2 0.8 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2296 PF10058.4 EER23771.1 - 0.03 14.0 1.5 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_ribbon_recom PF13408.1 EER23771.1 - 0.14 12.4 3.2 7 6.9 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.1 EER23771.1 - 1.2 8.9 5.9 5 7.0 0.4 3.1 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 NOB1_Zn_bind PF08772.6 EER23771.1 - 2.6 7.9 5.1 2.4 8.0 0.4 2.2 1 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like TF_Zn_Ribbon PF08271.7 EER23771.1 - 8.8 5.7 6.5 0.5 9.7 0.2 2.1 3 0 0 3 3 3 0 TFIIB zinc-binding LOH1CR12 PF10158.4 EER23772.1 - 0.07 12.9 1.0 0.36 10.6 0.2 2.2 2 0 0 2 2 2 0 Tumour suppressor protein MtrG PF04210.8 EER23772.1 - 0.28 10.8 7.3 6.5 6.4 0.3 3.4 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF2317 PF10079.4 EER23772.1 - 1 7.8 10.4 0.017 13.7 1.8 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) Phage_GPO PF05929.6 EER23772.1 - 1.2 8.3 8.9 0.052 12.8 1.8 1.9 2 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4164 PF13747.1 EER23772.1 - 3.6 7.7 11.3 0.63 10.2 0.3 4.0 3 2 2 5 5 5 0 Domain of unknown function (DUF4164) ArfGap PF01412.13 EER23773.1 - 3.3e-40 136.5 1.2 5.2e-40 135.8 0.8 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Synaptobrevin PF00957.16 EER23774.1 - 0.11 12.0 0.8 6.6 6.4 0.0 2.1 1 1 1 2 2 2 0 Synaptobrevin Dispanin PF04505.7 EER23774.1 - 0.12 11.9 0.3 0.2 11.2 0.2 1.3 1 0 0 1 1 1 0 Interferon-induced transmembrane protein DUF2422 PF10337.4 EER23775.1 - 6.3e-55 186.7 14.7 7.7e-55 186.4 1.0 3.3 2 2 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EER23775.1 - 1.4e-14 54.0 17.3 1.4e-14 54.0 12.0 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EER23775.1 - 5e-11 42.6 0.0 5.2e-09 36.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) ALMT PF11744.3 EER23775.1 - 5.9e-05 21.9 13.8 9.1e-05 21.2 7.6 2.3 2 1 0 2 2 2 1 Aluminium activated malate transporter Zds_C PF08632.5 EER23776.1 - 4.3e-29 99.6 2.4 9.8e-29 98.5 1.7 1.7 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF500 PF04366.7 EER23777.1 - 7.3e-44 148.2 0.2 1.4e-43 147.3 0.1 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EER23777.1 - 2e-13 49.4 0.3 5.8e-13 47.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EER23777.1 - 3.1e-12 45.8 0.1 6.2e-12 44.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EER23777.1 - 1e-11 44.1 0.3 4.4e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain Miro PF08477.8 EER23778.1 - 1.6e-36 125.3 0.0 1.3e-18 67.6 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EER23778.1 - 6.9e-34 115.4 0.0 1.2e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EER23778.1 - 1.3e-31 107.6 0.2 2.2e-31 106.9 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EER23778.1 - 8.2e-24 83.8 0.0 1.3e-13 50.7 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EER23778.1 - 4.2e-08 33.1 0.0 0.00072 19.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EER23778.1 - 5.6e-07 29.6 1.0 0.0038 17.3 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.1 EER23778.1 - 8.1e-06 25.9 1.9 0.047 13.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_1 PF00036.27 EER23778.1 - 2e-05 23.5 2.3 0.058 12.7 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EER23778.1 - 2.1e-05 24.0 2.4 0.051 13.4 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_29 PF13555.1 EER23778.1 - 2.2e-05 23.9 0.6 0.013 14.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Dynamin_N PF00350.18 EER23778.1 - 4.4e-05 23.3 0.4 0.42 10.4 0.1 3.1 2 1 0 3 3 3 2 Dynamin family AAA_22 PF13401.1 EER23778.1 - 0.00034 20.7 0.1 0.68 10.0 0.0 2.8 2 1 1 3 3 3 1 AAA domain EF-hand_10 PF14788.1 EER23778.1 - 0.0015 18.1 1.4 0.24 11.0 0.1 2.6 3 0 0 3 3 2 1 EF hand MobB PF03205.9 EER23778.1 - 0.0017 18.0 0.0 0.22 11.2 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_8 PF13833.1 EER23778.1 - 0.0021 17.6 0.3 0.67 9.6 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair NACHT PF05729.7 EER23778.1 - 0.0025 17.5 0.1 2 8.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Viral_helicase1 PF01443.13 EER23778.1 - 0.0073 15.8 0.2 0.14 11.6 0.0 2.7 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EER23778.1 - 0.01 16.1 0.1 7.6 6.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 EER23778.1 - 0.017 14.5 0.1 2.7 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EER23778.1 - 0.019 13.8 0.4 0.92 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 EER23778.1 - 0.019 14.3 0.1 11 5.4 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 EER23778.1 - 0.02 14.8 0.0 9.8 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EER23778.1 - 0.022 14.9 0.0 0.97 9.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 EER23778.1 - 0.023 14.3 0.1 0.11 12.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EER23778.1 - 0.024 14.1 0.1 12 5.3 0.1 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF258 PF03193.11 EER23778.1 - 0.033 13.3 0.1 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 EF-hand_5 PF13202.1 EER23778.1 - 0.057 12.7 3.2 1.7 8.1 0.3 2.6 2 0 0 2 2 2 0 EF hand Septin PF00735.13 EER23778.1 - 0.066 12.2 0.0 0.75 8.7 0.0 2.2 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 EER23778.1 - 0.08 12.6 0.0 6.2 6.4 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EER23778.1 - 0.082 12.3 0.0 13 5.1 0.0 2.5 2 1 0 2 2 2 0 AAA-like domain SMC_N PF02463.14 EER23778.1 - 0.11 11.6 0.6 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EER23778.1 - 0.14 12.4 0.2 23 5.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EER23778.1 - 0.21 11.4 0.4 17 5.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain IIGP PF05049.8 EER23778.1 - 0.23 10.2 0.9 0.78 8.4 0.2 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) TrwB_AAD_bind PF10412.4 EER23778.1 - 0.28 9.7 0.4 5.8 5.4 0.1 2.3 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.12 EER23778.1 - 0.32 10.5 2.4 25 4.3 0.0 3.2 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein WD40 PF00400.27 EER23779.1 - 4.9e-21 73.7 13.2 1.3e-07 31.2 0.5 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat IKI3 PF04762.7 EER23779.1 - 0.00013 20.0 0.0 0.00038 18.4 0.0 1.6 1 1 1 2 2 2 1 IKI3 family eIF2A PF08662.6 EER23779.1 - 0.0048 16.6 0.0 0.023 14.4 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EER23779.1 - 0.034 12.4 0.0 0.089 11.0 0.0 1.7 1 0 0 1 1 1 0 Cytochrome D1 heme domain PD40 PF07676.7 EER23779.1 - 0.039 13.6 0.0 3.3 7.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat DUF1273 PF06908.6 EER23779.1 - 0.05 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) Arrestin_C PF02752.17 EER23780.1 - 1.2e-10 41.6 0.0 1.5e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EER23780.1 - 1.8e-10 40.7 0.0 4.4e-10 39.5 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EER23780.1 - 0.0063 16.0 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Retinal PF15449.1 EER23781.1 - 0.015 12.9 5.6 0.024 12.3 3.9 1.2 1 0 0 1 1 1 0 Retinal protein ApoO PF09769.4 EER23781.1 - 0.15 11.8 2.9 4.2 7.0 0.1 2.8 2 1 1 3 3 3 0 Apolipoprotein O Glyoxalase PF00903.20 EER23782.1 - 2.2e-38 131.1 0.0 3.1e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EER23782.1 - 8.8e-32 109.9 0.1 1.4e-14 54.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EER23782.1 - 6.6e-18 64.7 0.0 3.9e-06 26.8 0.0 4.2 2 2 2 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EER23782.1 - 5.2e-05 23.2 0.0 0.26 11.1 0.0 3.3 2 1 0 2 2 2 2 Glyoxalase-like domain DUF4105 PF13387.1 EER23782.1 - 0.019 14.1 0.0 26 3.9 0.0 3.8 3 1 2 5 5 5 0 Domain of unknown function (DUF4105) Yqai PF09466.5 EER23783.1 - 0.18 11.8 0.2 0.37 10.8 0.1 1.4 1 0 0 1 1 1 0 Hypothetical protein Yqai Fe-ADH PF00465.14 EER23784.1 - 1.4e-100 336.4 0.0 1.9e-100 336.0 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EER23784.1 - 2e-17 63.3 0.1 1e-13 51.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EER23784.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein 2-Hacid_dh_C PF02826.14 EER23785.1 - 2.3e-56 189.7 0.0 4e-56 188.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER23785.1 - 4e-36 123.4 0.2 7.5e-36 122.5 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EER23785.1 - 0.022 14.5 2.3 0.025 14.4 0.1 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EER23785.1 - 0.44 10.1 4.8 0.65 9.5 0.7 2.6 2 1 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain UCH_1 PF13423.1 EER23786.1 - 1.1e-69 235.1 4.1 1.1e-69 235.1 2.8 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EER23786.1 - 1.4e-18 67.6 0.0 5.9e-17 62.4 0.0 2.4 2 0 0 2 2 2 1 Exonuclease UCH PF00443.24 EER23786.1 - 7.6e-09 35.0 0.5 1.2e-08 34.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase KH_1 PF00013.24 EER23787.1 - 1.7e-93 306.2 17.4 9.5e-13 47.5 0.1 13.1 14 0 0 14 14 14 10 KH domain KH_3 PF13014.1 EER23787.1 - 1.5e-67 222.3 16.2 2.5e-10 39.7 0.3 13.3 14 0 0 14 14 14 9 KH domain KH_2 PF07650.12 EER23787.1 - 1.1e-11 44.0 15.2 0.0029 17.1 0.2 8.1 8 0 0 8 8 8 3 KH domain SLS PF14611.1 EER23787.1 - 1.6e-09 37.5 4.1 0.073 12.4 0.0 6.8 6 1 0 6 6 6 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 EER23787.1 - 0.0024 17.4 2.6 3.5 7.3 0.0 5.8 6 0 0 6 6 6 1 KH domain BMC PF00936.14 EER23787.1 - 0.22 11.2 1.3 4.9 6.9 0.0 3.6 5 0 0 5 5 5 0 BMC domain Pkinase PF00069.20 EER23788.1 - 5.4e-71 238.7 0.0 8.5e-71 238.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23788.1 - 1.3e-45 155.4 0.0 2.1e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EER23788.1 - 2e-20 72.9 0.1 1.1e-19 70.5 0.1 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EER23788.1 - 1.7e-07 30.5 0.0 2.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DSHCT PF08148.7 EER23788.1 - 0.0019 17.4 0.0 0.0048 16.1 0.0 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ino80_Iec3 PF14612.1 EER23788.1 - 0.099 12.6 3.4 0.19 11.7 2.3 1.4 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling APH PF01636.18 EER23788.1 - 0.12 12.0 3.0 0.2 11.3 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family Paramyxo_C PF01692.13 EER23788.1 - 2 8.0 5.5 4.5 6.8 3.8 1.5 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c VHS PF00790.14 EER23789.1 - 1.9e-34 118.3 0.5 3.3e-34 117.5 0.4 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EER23789.1 - 5.7e-17 60.8 0.1 1.6e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EER23789.1 - 9.1e-16 57.1 0.1 1.8e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EER23789.1 - 3.1e-14 52.1 0.0 7.5e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EER23789.1 - 0.011 15.2 1.9 0.031 13.8 1.3 1.9 1 0 0 1 1 1 0 Ubiquitin interaction motif K_trans PF02705.11 EER23790.1 - 4.7e-132 441.0 20.4 1e-67 228.7 5.8 3.0 1 1 1 2 2 2 2 K+ potassium transporter Peptidase_M50 PF02163.17 EER23790.1 - 4.9 6.0 13.5 86 1.9 9.3 2.4 1 1 0 1 1 1 0 Peptidase family M50 Cyt-b5 PF00173.23 EER23791.1 - 1.5e-23 82.3 0.0 1.8e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ATPase_gene1 PF09527.5 EER23791.1 - 0.055 13.2 1.2 0.089 12.6 0.8 1.3 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) GTP_EFTU PF00009.22 EER23792.1 - 2e-51 174.1 0.0 3.5e-51 173.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EER23792.1 - 1.2e-21 76.6 2.2 2.3e-21 75.6 1.5 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.12 EER23792.1 - 2.2e-08 34.1 0.0 1.7e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.18 EER23792.1 - 9e-08 32.0 0.0 3.3e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EER23792.1 - 1.8e-07 31.1 0.0 3.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 EER23792.1 - 7.5e-05 23.2 0.0 0.001 19.5 0.0 2.7 2 1 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EER23792.1 - 0.00058 19.0 0.0 0.0013 17.9 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EER23792.1 - 0.0083 15.4 0.0 0.21 10.8 0.0 2.8 2 1 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU_D4 PF14578.1 EER23792.1 - 0.036 13.6 0.0 0.071 12.7 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu domain 4 G-alpha PF00503.15 EER23792.1 - 0.038 12.6 1.6 0.06 12.0 0.5 1.7 2 0 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 EER23792.1 - 0.058 12.5 1.8 1.7 7.8 0.0 2.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Di19_C PF14571.1 EER23792.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.1 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal HSP70 PF00012.15 EER23793.1 - 1.5e-264 878.4 13.9 1.7e-264 878.3 9.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EER23793.1 - 7.6e-19 67.4 2.1 1.1e-17 63.6 0.2 2.1 1 1 1 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EER23793.1 - 0.00025 20.2 4.9 0.19 10.7 0.3 3.4 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase DDR PF08841.5 EER23793.1 - 0.001 17.9 1.7 0.013 14.3 1.0 2.3 1 1 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EER23793.1 - 0.092 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.6 EER23793.1 - 0.27 10.1 8.0 0.016 14.2 1.8 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 FtsA PF14450.1 EER23793.1 - 2.2 8.1 8.8 4.4 7.1 0.1 3.9 4 1 0 4 4 4 0 Cell division protein FtsA UCH PF00443.24 EER23795.1 - 4.3e-57 193.2 0.0 6.1e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER23795.1 - 1e-30 107.2 0.0 1.7e-30 106.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EER23795.1 - 1.7e-05 25.1 0.0 3.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.14 EER23796.1 - 6e-28 97.2 0.2 1.2e-20 73.6 0.0 2.4 1 1 1 2 2 2 2 VHS domain UIM PF02809.15 EER23796.1 - 0.00057 19.2 9.6 0.011 15.2 0.8 2.9 2 0 0 2 2 2 2 Ubiquitin interaction motif Ribosomal_S30AE PF02482.14 EER23796.1 - 0.0066 16.8 0.3 0.021 15.2 0.2 1.8 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein TCO89 PF10452.4 EER23797.1 - 1.6e-07 30.6 13.8 0.00055 18.9 0.0 3.4 3 0 0 3 3 3 2 TORC1 subunit TCO89 RCC1 PF00415.13 EER23798.1 - 3.1e-22 78.5 0.1 3.6e-08 33.4 0.0 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EER23798.1 - 5.4e-16 58.5 0.0 9.7e-08 31.9 0.0 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EER23798.1 - 3.1e-09 37.0 0.1 2.1e-07 31.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EER23798.1 - 3.7e-08 32.7 1.7 9.1e-06 25.1 0.0 3.2 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EER23798.1 - 2.6e-07 30.2 0.5 0.026 14.7 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EER23798.1 - 1.3e-06 28.6 0.4 6.5e-05 23.1 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EER23798.1 - 4.6e-06 26.7 1.0 0.0026 17.9 0.2 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EER23798.1 - 0.00018 21.1 3.2 0.093 12.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat ATG13 PF10033.4 EER23799.1 - 1.8e-72 243.5 0.0 2.8e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 Cupin_1 PF00190.17 EER23800.1 - 2.7e-05 23.6 0.0 3.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EER23800.1 - 0.00015 21.1 1.3 0.00045 19.6 0.9 1.7 1 1 0 1 1 1 1 Cupin domain ARD PF03079.9 EER23800.1 - 0.0081 16.1 0.1 0.012 15.5 0.1 1.2 1 0 0 1 1 1 1 ARD/ARD' family GPI PF06560.6 EER23800.1 - 0.019 13.9 0.2 0.026 13.5 0.1 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) AraC_binding PF02311.14 EER23800.1 - 0.026 14.2 0.4 0.043 13.5 0.3 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.7 EER23800.1 - 0.043 13.2 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EER23800.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin NUC153 PF08159.7 EER23801.1 - 1.3e-14 53.4 1.1 3.2e-14 52.2 0.8 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EER23801.1 - 2.7e-07 30.1 0.1 0.04 13.8 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat Med13_C PF06333.7 EER23802.1 - 1e-100 337.2 0.0 1.8e-100 336.4 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EER23802.1 - 4.6e-23 81.5 0.0 1e-22 80.3 0.0 1.6 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Herpes_US9 PF06072.6 EER23802.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Ribosomal_L33 PF00471.15 EER23804.1 - 0.00072 19.7 0.0 0.00087 19.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Calici_coat PF00915.15 EER23805.1 - 0.0064 15.4 0.4 0.02 13.8 0.2 1.8 1 0 0 1 1 1 1 Calicivirus coat protein Reo_sigmaC PF04582.7 EER23805.1 - 0.48 9.5 39.6 0.025 13.7 6.1 4.8 2 2 3 5 5 5 0 Reovirus sigma C capsid protein MFS_1 PF07690.11 EER23807.1 - 6.4e-37 127.0 53.6 6.4e-37 127.0 37.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER23807.1 - 2.1e-14 52.6 22.3 4.5e-14 51.5 15.5 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EER23807.1 - 0.021 12.9 1.6 0.046 11.7 0.1 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF1514 PF07438.6 EER23807.1 - 0.19 11.6 0.5 6.7 6.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) Ceramidase PF05875.7 EER23808.1 - 4.6e-72 242.3 8.2 5.3e-72 242.1 5.7 1.0 1 0 0 1 1 1 1 Ceramidase FA_hydroxylase PF04116.8 EER23809.1 - 4.2e-16 59.3 9.4 4.2e-16 59.3 6.5 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 EER23810.1 - 7.5e-23 81.2 0.2 9.2e-22 77.7 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EER23810.1 - 1.6e-10 40.9 0.3 6.9e-10 38.8 0.2 2.0 2 1 0 2 2 2 1 KR domain F420_oxidored PF03807.12 EER23810.1 - 0.0001 22.6 0.2 0.00026 21.3 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EER23810.1 - 0.0012 18.8 0.2 0.003 17.5 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EER23810.1 - 0.0012 18.3 0.0 0.0019 17.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ApbA PF02558.11 EER23810.1 - 0.0038 16.6 0.1 0.0077 15.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA adh_short_C2 PF13561.1 EER23810.1 - 0.0046 16.7 0.0 0.0059 16.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2088 PF09861.4 EER23810.1 - 0.0099 14.9 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2088) DUF1776 PF08643.5 EER23810.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_transf_4 PF13439.1 EER23810.1 - 0.029 14.1 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 3HCDH_N PF02737.13 EER23810.1 - 0.036 13.7 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EER23810.1 - 0.045 12.6 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EER23810.1 - 0.055 13.4 0.2 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EER23810.1 - 0.084 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_2 PF03446.10 EER23810.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Aminotran_1_2 PF00155.16 EER23811.1 - 3.7e-23 82.0 0.0 4.9e-19 68.5 0.0 3.1 3 0 0 3 3 3 3 Aminotransferase class I and II FKBP_C PF00254.23 EER23812.1 - 1.7e-29 101.6 0.0 2e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cellulase PF00150.13 EER23813.1 - 1.7e-09 37.3 0.2 5.8e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 EER23813.1 - 0.025 14.9 0.4 0.22 11.9 0.0 2.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 EER23814.1 - 1.8e-59 201.0 0.0 2.5e-59 200.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23814.1 - 5.8e-32 110.7 0.0 7.8e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER23814.1 - 6.7e-05 21.9 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER23814.1 - 0.0024 17.6 1.0 0.0043 16.8 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EER23814.1 - 0.015 14.3 0.1 0.028 13.4 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 EER23814.1 - 2 7.7 9.4 2.6 7.3 6.5 1.1 1 0 0 1 1 1 0 Vta1 like SNF2_N PF00176.18 EER23815.1 - 2.8e-70 236.4 0.0 5.2e-70 235.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER23815.1 - 4e-11 42.6 0.0 1.6e-10 40.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SIR2 PF02146.12 EER23816.1 - 5.9e-38 130.3 0.0 3.5e-37 127.8 0.0 1.9 1 1 0 1 1 1 1 Sir2 family Pyridox_ox_2 PF12900.2 EER23817.1 - 7.1e-39 132.8 0.0 9e-39 132.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FR47 PF08445.5 EER23818.1 - 2.9e-06 26.9 0.1 0.00049 19.7 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_1 PF00583.19 EER23818.1 - 0.0003 20.7 0.7 0.00097 19.1 0.5 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EER23818.1 - 0.00062 19.9 0.1 0.00098 19.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER23818.1 - 0.0031 17.5 0.0 0.0093 16.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER23818.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase p450 PF00067.17 EER23819.1 - 3.8e-53 180.6 0.0 5e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EER23820.1 - 1e-14 54.5 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER23820.1 - 2.4e-08 34.5 0.0 1.8e-07 31.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23820.1 - 2.5e-08 34.2 0.0 4.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER23820.1 - 6.8e-08 32.2 0.0 4.3e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER23820.1 - 2.5e-06 27.8 0.0 7.6e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER23820.1 - 1.1e-05 25.7 0.0 2.7e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER23820.1 - 6e-05 23.0 0.0 0.00018 21.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER23820.1 - 0.00039 19.6 0.0 0.16 11.0 0.0 3.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EER23820.1 - 0.0017 17.7 0.0 0.005 16.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EER23820.1 - 0.0029 17.0 0.0 0.0054 16.1 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.7 EER23820.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EER23820.1 - 0.04 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EER23820.1 - 0.098 11.6 0.0 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Peptidase_M24 PF00557.19 EER23821.1 - 6.4e-50 169.6 0.0 9.3e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EER23821.1 - 2.5e-27 94.8 0.0 5.7e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF2920 PF11144.3 EER23821.1 - 0.24 10.3 1.5 2.7 6.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2920) Dfp1_Him1_M PF08630.5 EER23822.1 - 8.1e-42 141.9 0.1 2.8e-41 140.2 0.0 1.9 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 EER23822.1 - 1.5e-22 78.9 0.1 3e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EER23822.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain F-box-like PF12937.2 EER23823.1 - 0.0016 18.0 0.1 0.0032 17.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER23823.1 - 0.0025 17.4 0.1 0.02 14.5 0.0 2.4 2 0 0 2 2 2 1 F-box domain Pantoate_transf PF02548.10 EER23824.1 - 6.2e-105 350.0 1.2 7.4e-105 349.7 0.8 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EER23824.1 - 8.1e-10 38.3 0.9 1.8e-09 37.2 0.6 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PA PF02225.17 EER23824.1 - 0.02 14.5 1.4 0.44 10.2 0.1 2.3 2 0 0 2 2 2 0 PA domain APG12 PF04110.8 EER23825.1 - 9.3e-30 102.6 0.0 1.4e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EER23825.1 - 0.047 13.6 0.0 0.065 13.2 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like NmrA PF05368.8 EER23826.1 - 2.6e-29 102.1 0.3 3.2e-29 101.8 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EER23826.1 - 4.2e-13 49.7 0.4 7.4e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EER23826.1 - 0.00012 22.3 0.9 0.00056 20.2 0.1 2.3 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EER23826.1 - 0.0038 15.9 0.0 0.0073 15.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EER23826.1 - 0.0054 16.6 0.6 0.013 15.3 0.1 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EER23826.1 - 0.033 13.8 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 EER23826.1 - 0.079 12.3 0.1 0.71 9.2 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EER23826.1 - 0.1 12.6 0.4 1.2 9.1 0.1 2.3 2 1 0 2 2 2 0 TrkA-N domain DUF1471 PF07338.8 EER23826.1 - 0.14 11.7 2.8 0.16 11.6 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1471) adh_short PF00106.20 EER23826.1 - 0.16 11.8 1.2 0.49 10.2 0.2 2.3 2 1 1 3 3 3 0 short chain dehydrogenase UQ_con PF00179.21 EER23827.1 - 1.3e-36 125.0 0.0 1.6e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.1 EER23828.1 - 7.4e-23 80.6 0.1 1.5e-22 79.6 0.0 1.5 1 1 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2011 PF09428.5 EER23829.1 - 2.2e-40 137.5 5.2 3.4e-40 136.9 3.6 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) D123 PF07065.9 EER23831.1 - 1.2e-06 27.8 0.0 3.9e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 D123 DUF4343 PF14243.1 EER23831.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Homoserine_dh PF00742.14 EER23831.1 - 0.039 13.6 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Homoserine dehydrogenase ETC_C1_NDUFA5 PF04716.9 EER23831.1 - 0.11 11.9 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 ETC complex I subunit conserved region Sulfotransfer_3 PF13469.1 EER23832.1 - 0.0025 18.7 1.5 0.0089 16.9 1.0 1.9 1 1 0 1 1 1 1 Sulfotransferase family Cerato-platanin PF07249.7 EER23833.1 - 1.1e-48 164.1 0.2 1.3e-48 163.8 0.2 1.0 1 0 0 1 1 1 1 Cerato-platanin Barwin PF00967.12 EER23833.1 - 0.0011 18.5 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Barwin family p450 PF00067.17 EER23834.1 - 1.7e-16 59.8 0.1 5.2e-14 51.6 0.0 3.1 2 1 0 2 2 2 2 Cytochrome P450 MFS_1 PF07690.11 EER23835.1 - 2.7e-43 148.0 53.5 2.7e-43 148.0 37.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER23835.1 - 3.9e-16 58.6 37.0 2e-15 56.3 8.1 3.2 1 1 0 2 2 2 2 Sugar (and other) transporter Flavoprotein PF02441.14 EER23836.1 - 3.7e-12 46.0 0.0 7.4e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 EER23836.1 - 0.015 15.7 0.0 0.97 10.0 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeats (many copies) 3HCDH_N PF02737.13 EER23837.1 - 4.9e-30 104.5 0.0 6.9e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EER23837.1 - 3.3e-24 85.1 0.0 5.9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EER23837.1 - 4.5e-06 26.4 0.0 6.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EER23837.1 - 0.0019 17.6 0.0 0.0074 15.7 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EER23837.1 - 0.0081 16.5 0.0 0.018 15.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EER23837.1 - 0.039 12.9 0.0 0.077 11.9 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EER23837.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EER23837.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Asparaginase_2 PF01112.13 EER23838.1 - 1.2e-34 119.5 0.2 1.6e-28 99.3 0.0 4.2 3 1 0 3 3 3 3 Asparaginase TraQ PF09679.5 EER23839.1 - 0.0047 16.8 0.4 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 Type-F conjugative transfer system pilin chaperone (TraQ) Peptidase_M20 PF01546.23 EER23840.1 - 9.9e-26 90.4 0.0 4.8e-24 84.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase family M20/M25/M40 WD40 PF00400.27 EER23840.1 - 4.5e-17 61.2 7.2 7.8e-05 22.4 0.0 6.2 5 1 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.9 EER23840.1 - 8.3e-07 28.7 0.0 1.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF747 PF05346.6 EER23841.1 - 7.7e-128 426.2 5.2 1e-127 425.7 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DctQ PF04290.7 EER23842.1 - 0.081 12.6 7.4 1.2 8.8 0.9 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF202 PF02656.10 EER23842.1 - 0.27 11.4 8.0 0.85 9.8 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF21 PF01595.15 EER23843.1 - 5.9e-32 110.4 0.3 9.4e-32 109.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EER23843.1 - 1.6e-05 24.5 0.2 0.06 13.1 0.0 2.7 2 0 0 2 2 2 2 CBS domain T4_Gp59_C PF08994.5 EER23843.1 - 0.22 11.7 0.0 0.47 10.6 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term IncA PF04156.9 EER23844.1 - 0.00059 19.4 1.3 0.00059 19.4 0.9 5.3 2 1 3 5 5 5 3 IncA protein PspA_IM30 PF04012.7 EER23844.1 - 0.0019 17.5 17.8 0.0019 17.5 12.3 5.1 3 3 2 5 5 5 2 PspA/IM30 family Filament PF00038.16 EER23844.1 - 0.003 17.0 57.4 0.27 10.6 11.6 3.6 2 1 1 3 3 3 3 Intermediate filament protein Reo_sigmaC PF04582.7 EER23844.1 - 0.0033 16.6 19.1 0.22 10.6 1.5 3.9 2 1 1 4 4 4 4 Reovirus sigma C capsid protein GAS PF13851.1 EER23844.1 - 0.024 13.8 54.2 0.041 13.0 3.3 5.3 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EER23844.1 - 0.69 9.7 25.9 3.9 7.2 0.1 6.1 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) ATG_C PF09333.6 EER23844.1 - 4.5 7.4 9.4 4.4 7.5 0.0 4.1 3 2 2 5 5 5 0 ATG C terminal domain DUF948 PF06103.6 EER23844.1 - 6.2 6.7 18.5 3.3 7.6 0.9 5.9 6 1 2 8 8 8 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 EER23844.1 - 8.5 5.9 0.0 3.4 7.2 0.0 9.0 5 2 4 9 9 9 0 Septum formation initiator Transket_pyr PF02779.19 EER23845.1 - 2.7e-40 137.7 0.0 4e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EER23845.1 - 4.9e-30 104.0 0.0 1.4e-29 102.5 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain His_Phos_1 PF00300.17 EER23846.1 - 5.1e-13 49.4 0.0 1.1e-12 48.3 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) HECT PF00632.20 EER23847.1 - 3.6e-72 243.2 0.0 5.5e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 EER23848.1 - 4.6e-40 135.8 10.2 3e-32 110.7 3.4 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EER23848.1 - 1.1e-06 28.2 3.8 0.021 14.7 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EER23848.1 - 3.3e-06 27.1 2.0 3.3e-06 27.1 1.4 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EER23848.1 - 3.5e-06 26.9 5.8 0.00012 22.1 1.4 4.7 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding DUF2024 PF09630.5 EER23848.1 - 4.2e-05 23.1 2.0 0.021 14.5 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF2024) SnoaL_2 PF12680.2 EER23848.1 - 0.0034 17.7 0.0 0.012 15.9 0.0 1.9 2 0 0 2 2 2 1 SnoaL-like domain Rotamase_2 PF13145.1 EER23848.1 - 0.05 14.2 1.0 0.18 12.4 0.7 2.0 1 1 0 1 1 1 0 PPIC-type PPIASE domain Urm1 PF09138.6 EER23848.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Urm1 (Ubiquitin related modifier) zf-C2H2 PF00096.21 EER23848.1 - 0.08 13.3 0.5 0.08 13.3 0.4 5.3 5 0 0 5 5 5 0 Zinc finger, C2H2 type DUF4551 PF15087.1 EER23849.1 - 2.9 6.1 7.3 4.1 5.6 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Abhydrolase_3 PF07859.8 EER23850.1 - 1.4e-06 28.0 0.0 3.1e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EER23850.1 - 0.00083 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EER23850.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EER23850.1 - 0.015 15.1 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER23850.1 - 0.017 14.8 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EER23850.1 - 0.024 13.3 0.1 0.037 12.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Esterase PF00756.15 EER23850.1 - 0.037 13.4 0.0 0.092 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative esterase LZ_Tnp_IS66 PF13007.2 EER23850.1 - 3.4 8.3 10.3 6.5 7.4 0.1 3.3 3 0 0 3 3 3 0 Transposase C of IS166 homeodomain Dishevelled PF02377.10 EER23850.1 - 4.9 7.4 8.3 9.4 6.5 1.3 3.0 2 1 1 3 3 3 0 Dishevelled specific domain Pkinase PF00069.20 EER23851.1 - 2.5e-72 243.1 0.0 3.1e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23851.1 - 1.2e-31 109.6 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER23851.1 - 0.00016 20.7 0.0 0.00032 19.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER23851.1 - 0.0037 17.0 0.1 0.0082 15.9 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EER23851.1 - 0.016 14.1 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EER23851.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL 2OG-FeII_Oxy_2 PF13532.1 EER23852.1 - 4.7e-32 111.4 0.0 4.2e-31 108.3 0.0 2.0 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EER23852.1 - 0.038 14.5 0.1 0.18 12.3 0.0 2.2 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Put_Phosphatase PF06888.7 EER23852.1 - 0.14 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative Phosphatase Amidase PF01425.16 EER23853.1 - 3e-92 309.7 0.0 4.1e-92 309.3 0.0 1.2 1 0 0 1 1 1 1 Amidase CMAS PF02353.15 EER23854.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DivIC PF04977.10 EER23854.1 - 0.32 10.5 6.0 0.43 10.0 1.2 2.8 3 0 0 3 3 3 0 Septum formation initiator adh_short PF00106.20 EER23855.1 - 9.7e-12 45.1 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER23855.1 - 6.9e-05 22.7 0.0 7.7e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER23855.1 - 0.00048 19.8 0.0 0.0006 19.5 0.0 1.1 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 EER23856.1 - 2.9e-12 46.0 0.1 4.3e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER23856.1 - 2.3e-06 27.4 10.1 5.6e-06 26.1 7.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPT PF03151.11 EER23857.1 - 6.7e-30 103.7 10.1 6.7e-30 103.7 7.0 2.4 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EER23857.1 - 0.59 8.9 27.4 0.05 12.5 15.4 1.7 2 0 0 2 2 2 0 UAA transporter family AD PF09793.4 EER23858.1 - 2.1e-25 88.4 0.0 2.9e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain 6PGD PF00393.14 EER23859.1 - 1.4e-134 447.8 0.0 1.9e-134 447.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EER23859.1 - 1.3e-51 174.7 0.0 1.8e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EER23859.1 - 0.016 15.2 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase RRM_1 PF00076.17 EER23860.1 - 9.8e-18 63.5 0.0 1.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER23860.1 - 1e-10 41.4 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER23860.1 - 0.00062 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hexokinase_2 PF03727.11 EER23861.1 - 3.2e-28 98.5 0.0 6.9e-23 81.1 0.0 2.1 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EER23861.1 - 1.9e-23 82.9 0.0 4.4e-22 78.4 0.0 2.4 1 1 0 1 1 1 1 Hexokinase AP_endonuc_2 PF01261.19 EER23862.1 - 2.2e-25 89.2 0.0 5.9e-25 87.8 0.0 1.7 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel HNH_2 PF13391.1 EER23863.1 - 6.7e-16 57.8 0.0 1.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Mad3_BUB1_I PF08311.7 EER23864.1 - 3.4e-42 143.2 0.0 6.7e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EER23864.1 - 2.6e-14 52.9 0.0 6.8e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER23864.1 - 0.0022 17.0 0.0 0.0089 15.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EER23864.1 - 0.014 15.2 0.0 0.048 13.5 0.0 2.0 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Peptidase_C15 PF01470.12 EER23867.1 - 2.1e-14 53.8 0.0 2.2e-07 30.9 0.0 2.6 2 1 0 2 2 2 2 Pyroglutamyl peptidase Tymo_45kd_70kd PF03251.8 EER23867.1 - 0.001 17.8 0.3 0.002 16.8 0.2 1.4 1 0 0 1 1 1 1 Tymovirus 45/70Kd protein DUF2036 PF09724.4 EER23867.1 - 0.16 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2036) AA_permease PF00324.16 EER23868.1 - 3.8e-109 365.1 41.3 4.7e-109 364.8 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER23868.1 - 1.8e-32 112.4 44.5 2.2e-32 112.1 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease DNA_pol_phi PF04931.8 EER23869.1 - 2.8e-73 247.0 20.7 1.7e-72 244.4 14.4 1.9 1 1 0 1 1 1 1 DNA polymerase phi CM_2 PF01817.16 EER23869.1 - 0.055 13.5 3.9 1.5 8.9 1.2 3.7 3 0 0 3 3 3 0 Chorismate mutase type II BUD22 PF09073.5 EER23869.1 - 0.058 12.4 23.2 0.12 11.4 16.1 1.4 1 0 0 1 1 1 0 BUD22 DDE_1 PF03184.14 EER23870.1 - 1.9e-32 112.1 0.0 3.3e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EER23870.1 - 0.0008 19.1 0.0 0.0023 17.6 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF455 PF04305.9 EER23870.1 - 0.051 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF455) Rhodanese PF00581.15 EER23871.1 - 1.7e-12 47.7 0.0 3.5e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Sld5 PF05916.6 EER23872.1 - 1.5e-09 38.0 0.3 2.4e-09 37.4 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein Cullin PF00888.17 EER23873.1 - 5.1e-129 431.4 8.4 8.1e-129 430.8 5.8 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EER23873.1 - 6.6e-28 96.3 0.6 2.5e-27 94.4 0.4 2.1 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-DNL PF05180.7 EER23874.1 - 9.2e-29 98.9 0.7 1.4e-28 98.4 0.5 1.3 1 0 0 1 1 1 1 DNL zinc finger TFIIS_C PF01096.13 EER23874.1 - 0.016 14.8 1.2 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) E7 PF00527.13 EER23874.1 - 0.16 12.1 0.8 1.8 8.7 0.0 2.6 3 0 0 3 3 3 0 E7 protein, Early protein DRIM PF07539.7 EER23875.1 - 2.4e-48 163.1 0.0 1.2e-47 160.8 0.0 2.3 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 EER23875.1 - 0.061 13.4 2.3 2.2 8.6 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat CwfJ_C_1 PF04677.10 EER23876.1 - 8.2e-25 86.8 0.0 1.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EER23876.1 - 3.1e-22 78.9 0.3 8.6e-22 77.4 0.1 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Metallophos PF00149.23 EER23876.1 - 0.0044 16.4 0.0 0.0081 15.5 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1730 PF08331.5 EER23876.1 - 0.063 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) DUF1413 PF07205.6 EER23876.1 - 0.22 11.0 0.9 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) MFS_1 PF07690.11 EER23877.1 - 1.8e-17 63.0 56.5 1.5e-11 43.6 13.4 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily Corona_S2 PF01601.11 EER23878.1 - 0.06 11.4 13.1 0.081 11.0 9.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein RCR PF12273.3 EER23879.1 - 2.4e-27 96.0 8.6 2.8e-27 95.8 5.9 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EER23879.1 - 0.0063 16.1 0.2 0.0072 15.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Arf PF00025.16 EER23880.1 - 1.1e-42 145.2 0.0 1.3e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EER23880.1 - 3.8e-19 68.6 0.0 4.2e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER23880.1 - 1.2e-09 38.6 0.0 2.5e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EER23880.1 - 5.5e-07 28.9 0.0 7.2e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EER23880.1 - 6.3e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EER23880.1 - 1.2e-05 24.6 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EER23880.1 - 8.6e-05 21.3 0.0 0.00019 20.2 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.18 EER23880.1 - 0.0013 18.5 0.0 0.013 15.3 0.1 2.0 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EER23880.1 - 0.041 13.1 0.2 0.16 11.2 0.0 1.9 2 1 0 2 2 2 0 Ferrous iron transport protein B RNA_pol_Rpb2_6 PF00562.23 EER23881.1 - 2.9e-116 388.4 0.0 3.8e-116 388.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EER23881.1 - 2.6e-30 104.8 0.0 3.8e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EER23881.1 - 5.1e-26 91.2 0.0 9.5e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EER23881.1 - 1.4e-25 89.0 0.0 3.1e-25 87.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_3 PF04565.11 EER23881.1 - 7.8e-24 83.2 0.0 1.7e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EER23881.1 - 3.9e-15 55.8 0.0 1.7e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EER23881.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Proteasome PF00227.21 EER23882.1 - 4.1e-48 163.1 0.1 5e-48 162.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pil1 PF13805.1 EER23883.1 - 9.5e-92 306.9 2.6 1.2e-91 306.7 1.8 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 SWI-SNF_Ssr4 PF08549.5 EER23884.1 - 5.5e-230 765.2 9.9 6.3e-230 765.0 6.9 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Ppx-GppA PF02541.11 EER23885.1 - 5.4e-44 150.5 0.0 7e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.12 EER23885.1 - 0.019 13.4 0.1 0.03 12.7 0.0 1.2 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family MreB_Mbl PF06723.8 EER23885.1 - 0.15 10.5 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein Ofd1_CTDD PF10637.4 EER23886.1 - 0.086 11.9 1.2 0.13 11.3 0.8 1.4 1 1 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DMP1 PF07263.6 EER23886.1 - 7.1 5.2 18.7 2.1 6.9 5.2 2.1 1 1 1 2 2 2 0 Dentin matrix protein 1 (DMP1) Thi4 PF01946.12 EER23887.1 - 4.9e-101 336.6 0.0 5.8e-101 336.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EER23887.1 - 2.1e-08 33.4 0.0 2.5e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER23887.1 - 1.7e-05 24.7 1.1 5.3e-05 23.1 0.2 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EER23887.1 - 3e-05 23.1 0.4 5.3e-05 22.2 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EER23887.1 - 0.00028 20.6 0.3 0.00074 19.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EER23887.1 - 0.0019 18.0 0.2 0.0037 17.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER23887.1 - 0.0021 18.1 0.1 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EER23887.1 - 0.0041 16.0 0.8 0.017 13.9 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EER23887.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EER23887.1 - 0.07 12.1 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EER23887.1 - 0.093 11.3 0.3 0.13 10.8 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 EER23887.1 - 0.14 10.5 0.6 0.2 10.0 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Exo_endo_phos PF03372.18 EER23888.1 - 7.2e-17 62.1 0.0 1.1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lactamase_B PF00753.22 EER23888.1 - 0.1 12.2 0.1 3.5 7.2 0.0 2.5 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily WD40 PF00400.27 EER23889.1 - 4.7e-58 191.1 16.8 9.3e-14 50.6 0.5 8.9 8 1 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EER23889.1 - 3.2e-08 32.1 0.1 0.42 8.6 0.0 4.5 1 1 1 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EER23889.1 - 4.5e-06 26.5 0.0 0.011 15.5 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EER23889.1 - 0.0099 13.7 0.0 0.017 12.9 0.0 1.4 1 0 0 1 1 1 1 IKI3 family PD40 PF07676.7 EER23889.1 - 0.01 15.4 0.6 75 3.1 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 EER23889.1 - 0.084 11.7 0.0 0.8 8.5 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1513) DUF3312 PF11768.3 EER23889.1 - 0.22 9.7 0.0 0.34 9.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) TLP-20 PF06088.6 EER23889.1 - 0.6 9.7 4.7 1.7 8.2 3.3 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Lamp PF01299.12 EER23889.1 - 1.3 8.1 3.8 1.8 7.6 2.6 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) VID27 PF08553.5 EER23889.1 - 6.9 4.7 7.4 17 3.4 0.0 2.7 2 1 1 3 3 3 0 VID27 cytoplasmic protein Glyco_hydro_cc PF11790.3 EER23890.1 - 7.2e-57 192.5 0.0 8.6e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core RED_N PF07808.8 EER23891.1 - 1.9e-06 27.2 3.4 1.9e-06 27.2 2.3 1.9 2 0 0 2 2 2 1 RED-like protein N-terminal region zf-UBR PF02207.15 EER23892.1 - 8.7e-16 57.4 15.4 8.7e-16 57.4 10.7 2.1 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EER23892.1 - 2.6e-05 23.8 0.0 6.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS SDA1 PF05285.7 EER23892.1 - 4 6.6 6.7 7.1 5.8 4.7 1.3 1 0 0 1 1 1 0 SDA1 UCR_UQCRX_QCR9 PF05365.7 EER23893.1 - 2.3e-30 103.9 2.3 2.5e-30 103.8 1.6 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EER23894.1 - 1.2e-12 47.1 3.9 1.2e-12 47.1 2.7 2.0 2 0 0 2 2 2 1 Mago binding Nop53 PF07767.6 EER23894.1 - 0.043 12.8 11.6 0.054 12.4 8.0 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) NAD_binding_8 PF13450.1 EER23895.1 - 2.7e-14 52.9 0.0 7.8e-14 51.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EER23895.1 - 5.2e-14 52.1 0.1 3.4e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EER23895.1 - 3.2e-10 39.4 0.1 7e-09 35.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EER23895.1 - 1.4e-06 28.5 0.0 0.00011 22.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER23895.1 - 2.8e-05 24.2 0.0 0.0012 18.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER23895.1 - 0.00011 21.3 0.0 0.00042 19.4 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 EER23895.1 - 0.00055 19.7 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 EER23895.1 - 0.0025 17.5 0.0 0.038 13.7 0.0 2.5 3 0 0 3 3 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EER23895.1 - 0.0026 17.8 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EER23895.1 - 0.012 14.5 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EER23895.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EER23895.1 - 0.014 14.8 0.1 0.034 13.5 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EER23895.1 - 0.014 14.4 0.0 2.3 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 EER23895.1 - 0.018 14.1 0.1 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EER23895.1 - 0.018 15.3 0.0 4.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Strep_67kDa_ant PF06100.6 EER23895.1 - 0.024 12.9 0.1 0.058 11.7 0.0 1.6 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family HI0933_like PF03486.9 EER23895.1 - 0.031 12.7 0.0 0.11 10.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.1 EER23895.1 - 0.038 12.9 0.0 0.11 11.3 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EER23895.1 - 0.24 9.5 0.0 0.34 9.0 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like zf-CCCH_2 PF14608.1 EER23896.1 - 1.6e-07 30.9 54.9 0.00016 21.5 8.3 5.4 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EER23896.1 - 0.0045 17.0 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_hydro_20 PF00728.17 EER23897.1 - 2.1e-81 273.8 0.0 2.6e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EER23897.1 - 1.8e-21 77.1 0.0 4.8e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EER23897.1 - 8e-06 26.4 0.0 0.0004 20.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 EER23898.1 - 1.6e-60 204.9 0.0 1.8e-59 201.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 EER23899.1 - 1.1e-42 145.3 1.7 1.8e-42 144.7 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 tRNA-synt_1b PF00579.20 EER23901.1 - 2.8e-61 207.2 0.0 3.4e-61 206.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PP2C PF00481.16 EER23902.1 - 1.9e-52 178.2 0.1 3.1e-52 177.4 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EER23902.1 - 2.6e-50 167.3 52.2 1.3e-07 31.0 0.9 12.7 9 2 3 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER23902.1 - 6e-39 131.6 58.5 9.2e-09 34.9 2.5 9.3 4 2 7 11 11 11 11 Leucine rich repeat Guanylate_cyc PF00211.15 EER23902.1 - 5e-28 97.7 0.0 1.1e-27 96.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EER23902.1 - 3.6e-18 62.8 58.9 0.046 13.7 0.1 18.7 17 2 2 19 19 19 7 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 EER23902.1 - 3.1e-11 42.4 0.0 1.3e-10 40.4 0.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 EER23902.1 - 8.1e-08 31.2 56.8 0.45 10.9 0.1 16.4 18 1 1 19 19 19 2 Leucine rich repeat RA PF00788.18 EER23902.1 - 2.7e-07 30.9 0.0 7.9e-07 29.4 0.0 1.8 2 0 0 2 2 1 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.1 EER23902.1 - 0.0021 17.7 7.2 0.11 12.2 0.2 3.7 4 0 0 4 4 4 1 Leucine rich repeats (6 copies) Dynamin_M PF01031.15 EER23902.1 - 0.026 13.3 0.0 0.052 12.3 0.0 1.4 1 0 0 1 1 1 0 Dynamin central region LRR_6 PF13516.1 EER23902.1 - 0.087 12.9 55.5 1.7 8.9 0.4 15.3 17 1 0 17 17 17 0 Leucine Rich repeat LRR_9 PF14580.1 EER23902.1 - 0.33 10.4 10.7 1.3 8.5 0.3 4.2 2 1 1 4 4 4 0 Leucine-rich repeat LRR_2 PF07723.8 EER23902.1 - 3.5 8.2 5.6 72 4.1 0.0 4.4 4 0 0 4 4 3 0 Leucine Rich Repeat MSC PF09402.5 EER23903.1 - 1.7e-96 322.8 0.0 2.4e-96 322.3 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EER23903.1 - 4.9e-16 57.9 0.1 1.2e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.22 EER23903.1 - 0.052 13.0 0.2 3.3 7.3 0.0 3.5 3 0 0 3 3 3 0 SAP domain DUF2630 PF10944.3 EER23903.1 - 0.36 10.9 0.0 0.36 10.9 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2630) DUF3350 PF11830.3 EER23903.1 - 3 7.9 9.9 0.8 9.7 0.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3350) Aminotran_1_2 PF00155.16 EER23904.1 - 1.6e-76 257.6 0.0 1.9e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4066 PF13278.1 EER23905.1 - 2.3e-28 98.5 0.0 3e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EER23905.1 - 1.2e-11 44.2 0.0 2e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF1805 PF08827.6 EER23906.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) IMS PF00817.15 EER23907.1 - 1.2e-42 145.2 0.0 1.9e-41 141.3 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EER23907.1 - 2.9e-19 69.2 0.0 7.3e-19 67.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EER23907.1 - 2.1e-13 50.1 2.9 3.5e-06 26.8 0.3 3.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) BRCT PF00533.21 EER23907.1 - 5.1e-08 32.9 0.0 1.7e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EER23907.1 - 5e-05 23.0 0.0 0.00018 21.3 0.0 2.0 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 EER23907.1 - 0.00045 20.1 0.1 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.1 EER23907.1 - 0.0043 17.1 0.0 0.017 15.3 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain FKBP_C PF00254.23 EER23908.1 - 8.2e-32 109.1 0.0 3.2e-31 107.1 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase 2CSK_N PF08521.5 EER23908.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal Pkinase PF00069.20 EER23909.1 - 2.4e-49 167.8 0.2 1.7e-25 89.7 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EER23909.1 - 1.5e-21 76.6 0.0 8.6e-13 47.9 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EER23909.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3591 PF12157.3 EER23910.1 - 1.3e-195 650.1 0.1 1.9e-195 649.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EER23910.1 - 0.0034 17.0 1.1 0.0079 15.8 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EER23910.1 - 0.014 15.2 0.9 0.025 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle Afaf PF15339.1 EER23910.1 - 0.14 11.6 0.0 0.14 11.6 0.0 2.1 3 0 0 3 3 3 0 Acrosome formation-associated factor FlxA PF14282.1 EER23910.1 - 0.24 11.3 12.7 1.5 8.7 3.5 2.9 2 0 0 2 2 2 0 FlxA-like protein Methyltransf_15 PF09445.5 EER23911.1 - 4.9e-51 172.5 0.0 6.2e-51 172.2 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EER23911.1 - 1.4e-12 47.6 0.0 1.7e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EER23911.1 - 1.7e-10 40.9 0.0 2.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EER23911.1 - 5.1e-10 39.2 0.0 6.9e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EER23911.1 - 1.7e-08 34.9 0.0 2.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EER23911.1 - 1.1e-07 31.3 0.0 1.6e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EER23911.1 - 2.7e-06 27.0 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER23911.1 - 0.00027 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 EER23911.1 - 0.0024 16.9 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_5 PF01795.14 EER23911.1 - 0.0028 17.0 0.0 0.0037 16.5 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family PrmA PF06325.8 EER23911.1 - 0.0087 15.2 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DNA_methylase PF00145.12 EER23911.1 - 0.017 14.2 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase GRASP55_65 PF04495.9 EER23912.1 - 1.1e-42 145.3 0.0 2.2e-41 141.0 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain ApoO PF09769.4 EER23913.1 - 4.4e-49 166.2 0.1 1e-48 165.0 0.1 1.6 2 0 0 2 2 2 1 Apolipoprotein O RP1-2 PF12042.3 EER23913.1 - 0.029 14.0 0.7 0.068 12.8 0.5 1.6 1 0 0 1 1 1 0 Tubuliform egg casing silk strands structural domain Peptidase_M3 PF01432.15 EER23914.1 - 6.1e-123 411.2 0.0 7.9e-123 410.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EER23914.1 - 0.035 13.4 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like PA28_beta PF02252.13 EER23914.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Proteasome activator pa28 beta subunit APH PF01636.18 EER23915.1 - 5.1e-12 46.0 0.0 2.7e-11 43.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 EER23916.1 - 6.3e-13 49.0 0.8 1.9e-12 47.4 0.6 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER23916.1 - 9.7e-05 22.0 0.0 0.00013 21.6 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Proteasome PF00227.21 EER23919.1 - 4.8e-44 149.9 0.1 5.9e-44 149.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EER23919.1 - 1.8e-13 49.5 0.6 3.6e-13 48.5 0.4 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Pyr_redox_3 PF13738.1 EER23921.1 - 8.3e-25 88.0 0.0 1.2e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER23921.1 - 6e-14 51.1 0.0 1.1e-12 46.9 0.0 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EER23921.1 - 8.7e-09 35.2 0.0 3e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EER23921.1 - 2.3e-06 26.7 0.1 4.9e-05 22.4 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EER23921.1 - 0.00012 21.1 0.0 0.0069 15.3 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EER23921.1 - 0.00029 20.0 0.0 0.0016 17.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EER23921.1 - 0.00074 19.8 0.0 0.38 11.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER23921.1 - 0.0035 17.1 0.1 8.5 6.1 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EER23921.1 - 0.015 15.4 0.0 0.25 11.4 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EER23921.1 - 0.03 13.2 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EER23921.1 - 0.047 13.9 0.0 0.23 11.7 0.0 2.1 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 EER23921.1 - 0.17 11.7 0.0 12 5.7 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EER23922.1 - 5e-16 58.3 0.7 8.7e-16 57.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER23922.1 - 1.3e-07 31.3 9.6 2.6e-07 30.4 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ImpA-rel_N PF06812.7 EER23922.1 - 0.027 14.2 0.1 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 ImpA-related N-terminal Acetyltransf_7 PF13508.1 EER23924.1 - 5.8e-11 42.3 0.3 2.9e-10 40.1 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER23924.1 - 2.2e-09 37.2 0.0 6.9e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EER23924.1 - 1.1e-05 25.5 0.1 2.7e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER23924.1 - 0.00011 22.0 0.0 0.00059 19.6 0.0 2.2 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EER23924.1 - 0.00017 20.8 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family FR47 PF08445.5 EER23924.1 - 0.00075 19.2 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein ABM PF03992.11 EER23926.1 - 0.0014 18.5 0.1 0.15 12.1 0.0 2.2 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase KH_1 PF00013.24 EER23927.1 - 8.7e-39 130.9 2.5 9.3e-16 57.2 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EER23927.1 - 2.2e-28 97.3 11.0 2.2e-11 43.1 1.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EER23927.1 - 6.3e-10 38.4 2.0 0.014 14.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EER23927.1 - 0.00053 19.7 5.8 1.3 8.8 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_4 PF13083.1 EER23927.1 - 0.015 14.9 1.2 4.6 6.9 0.0 3.2 3 0 0 3 3 3 0 KH domain CENP-K PF11802.3 EER23928.1 - 0.00021 20.6 4.3 0.39 9.8 0.0 2.3 2 1 0 2 2 2 2 Centromere-associated protein K zf-C4H2 PF10146.4 EER23928.1 - 0.023 14.7 3.5 0.044 13.7 2.4 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein ATG11 PF10377.4 EER23928.1 - 0.058 13.2 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 Autophagy-related protein 11 OmpH PF03938.9 EER23928.1 - 0.39 10.6 17.4 0.096 12.6 4.8 2.5 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EER23928.1 - 0.9 8.5 8.9 1.8 7.5 2.3 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 EER23928.1 - 2.7 7.5 13.8 3.3 7.3 0.2 2.4 2 0 0 2 2 2 0 Mnd1 family Abhydrolase_6 PF12697.2 EER23929.1 - 3.9e-11 43.2 0.0 4e-10 39.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER23929.1 - 7.6e-10 38.7 0.0 1.3e-08 34.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER23929.1 - 1.8e-08 34.2 0.0 2.7e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EER23929.1 - 0.019 14.7 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 EER23929.1 - 0.045 13.1 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Pyridoxal_deC PF00282.14 EER23930.1 - 1.8e-29 102.3 0.0 3e-29 101.6 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EER23930.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EER23930.1 - 0.0021 17.0 0.0 0.0034 16.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II MR_MLE_C PF13378.1 EER23930.1 - 0.029 14.3 1.0 1.5 8.7 0.1 2.8 3 0 0 3 3 3 0 Enolase C-terminal domain-like RWP-RK PF02042.10 EER23930.1 - 0.07 12.9 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 RWP-RK domain Aminotran_5 PF00266.14 EER23930.1 - 0.14 10.9 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF4110 PF13422.1 EER23931.1 - 2.9e-32 110.3 1.3 2.9e-32 110.3 0.9 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EER23931.1 - 4.8e-30 103.0 9.5 2.2e-09 37.1 0.0 7.4 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EER23931.1 - 3.2e-25 87.6 10.9 1.8e-08 34.0 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EER23931.1 - 6.4e-21 73.8 2.1 2e-05 24.4 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EER23931.1 - 1.4e-19 69.0 3.6 8.9e-06 25.2 0.0 6.1 5 1 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 EER23931.1 - 1.5e-18 66.0 4.1 0.00072 19.6 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EER23931.1 - 1.6e-14 53.1 0.9 6.3e-06 25.6 0.1 5.5 5 1 0 5 5 5 2 Kelch motif DEAD PF00270.24 EER23932.1 - 8.6e-22 77.4 0.2 1e-20 73.9 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER23932.1 - 6e-21 74.1 0.2 3.2e-18 65.3 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RQC PF09382.5 EER23932.1 - 3.9e-20 71.5 0.0 1.2e-19 69.9 0.0 1.9 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EER23932.1 - 6.1e-07 29.0 0.0 1.5e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 EER23932.1 - 0.001 18.9 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EER23932.1 - 0.051 12.8 0.0 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 SecA DEAD-like domain Mon1 PF03164.9 EER23933.1 - 5e-121 404.1 0.0 6.1e-121 403.9 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.9 EER23934.1 - 1.1e-120 402.0 0.1 1.6e-119 398.2 0.0 2.7 3 0 0 3 3 3 1 Dopey, N-terminal DUF2096 PF09869.4 EER23934.1 - 0.095 12.5 0.1 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) zf-HIT PF04438.11 EER23936.1 - 1.1e-09 37.7 5.5 1.7e-09 37.1 3.8 1.3 1 0 0 1 1 1 1 HIT zinc finger MBOAT PF03062.14 EER23937.1 - 1.6e-43 149.0 18.0 1.6e-43 149.0 12.5 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family PufQ PF05398.6 EER23937.1 - 0.0018 18.2 0.2 3.1 7.8 0.0 2.5 2 0 0 2 2 2 2 PufQ cytochrome subunit adh_short PF00106.20 EER23938.1 - 4.9e-25 88.3 0.1 6.4e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER23938.1 - 6.4e-25 88.3 0.0 8.1e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER23938.1 - 1.3e-08 34.7 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EER23938.1 - 0.0016 18.1 0.0 0.0056 16.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EER23938.1 - 0.0033 16.8 0.0 0.0044 16.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EER23938.1 - 0.0047 16.0 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) OTCace PF00185.19 EER23938.1 - 0.029 14.2 0.1 0.073 12.9 0.0 1.5 1 1 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF2974 PF11187.3 EER23938.1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) THF_DHG_CYH_C PF02882.14 EER23938.1 - 0.034 13.2 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EER23938.1 - 0.12 12.3 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_7 PF13241.1 EER23938.1 - 0.19 11.9 0.9 0.42 10.8 0.6 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding polyprenyl_synt PF00348.12 EER23939.1 - 9.4e-40 136.0 0.0 1.5e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase AOX PF01786.12 EER23940.1 - 1.2e-90 302.4 0.1 1.5e-90 302.1 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase NADH-u_ox-rdase PF10785.4 EER23940.1 - 0.29 11.3 1.8 9.3 6.5 0.1 2.8 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Acylphosphatase PF00708.13 EER23941.1 - 2.4e-27 94.8 0.4 2.6e-27 94.7 0.3 1.0 1 0 0 1 1 1 1 Acylphosphatase BLUF PF04940.7 EER23941.1 - 0.00021 20.9 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Sensors of blue-light using FAD Med25_SD1 PF11235.3 EER23942.1 - 8.4 6.6 12.3 0.097 12.9 2.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 KAR9 PF08580.5 EER23943.1 - 6.5e-138 460.9 0.0 6.5e-138 460.9 0.0 2.1 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Tropomyosin PF00261.15 EER23943.1 - 0.013 14.6 0.2 0.027 13.5 0.2 1.4 1 0 0 1 1 1 0 Tropomyosin Spectrin PF00435.16 EER23943.1 - 0.61 10.4 5.9 4.9 7.5 0.6 3.4 3 1 0 3 3 3 0 Spectrin repeat zf-B_box PF00643.19 EER23944.1 - 6.3 6.7 12.6 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 B-box zinc finger Mito_carr PF00153.22 EER23945.1 - 7.8e-59 195.4 0.0 3.9e-18 64.9 0.0 4.1 3 2 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 EER23946.1 - 1.4e-09 37.5 0.4 2.5e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER23946.1 - 2.8e-05 23.6 0.0 7.7e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 F-box domain MIT PF04212.13 EER23946.1 - 0.11 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Cullin PF00888.17 EER23947.1 - 7.9e-48 163.3 0.5 2.5e-47 161.7 0.1 1.9 3 0 0 3 3 3 1 Cullin family APC2 PF08672.6 EER23947.1 - 2.4e-23 82.1 0.1 1.5e-22 79.5 0.0 2.4 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 EER23947.1 - 0.052 13.2 0.1 13 5.5 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator HTH_5 PF01022.15 EER23947.1 - 0.15 11.7 0.6 0.68 9.6 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Pkr1 PF08636.5 EER23948.1 - 2e-34 117.4 7.5 2.8e-34 116.9 5.2 1.2 1 0 0 1 1 1 1 ER protein Pkr1 zf-C2H2_4 PF13894.1 EER23949.1 - 5.9e-05 23.1 3.0 0.013 15.7 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EER23949.1 - 0.00087 19.4 4.6 0.39 11.1 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EER23949.1 - 0.19 11.7 1.2 21 5.1 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger GTP_EFTU PF00009.22 EER23950.1 - 8.5e-07 28.5 0.0 1.5e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EER23950.1 - 0.0037 17.5 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ATP_bind_1 PF03029.12 EER23950.1 - 0.033 13.7 0.1 8.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EER23950.1 - 0.048 12.8 0.1 0.09 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 LSM PF01423.17 EER23951.1 - 1.7e-16 59.4 0.0 2.3e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EER23951.1 - 0.00016 21.4 0.0 0.00025 20.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 EER23951.1 - 0.11 12.8 3.1 0.17 12.3 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) API5 PF05918.6 EER23951.1 - 1.4 7.3 8.4 1.7 7.0 5.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF3628 PF12300.3 EER23951.1 - 5.6 6.9 14.7 8 6.4 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) Methyltransf_26 PF13659.1 EER23952.1 - 2.3e-16 59.8 0.0 3.2e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EER23952.1 - 0.16 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EER23952.1 - 0.24 10.7 5.1 20 4.5 3.5 2.2 1 1 0 1 1 1 0 Methyltransferase small domain Complex1_LYR PF05347.10 EER23953.1 - 1.2e-09 37.7 0.4 2.4e-09 36.8 0.2 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EER23953.1 - 3.8e-08 33.4 0.1 5.7e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EER23953.1 - 3.1e-06 27.6 0.3 4e-06 27.2 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like TauD PF02668.11 EER23954.1 - 5.6e-24 85.2 0.0 6.8e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF1157 PF06636.6 EER23954.1 - 0.14 10.7 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1157) HA2 PF04408.18 EER23955.1 - 3.5e-17 62.2 0.1 6.9e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EER23955.1 - 1.6e-16 60.1 0.0 3.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EER23955.1 - 6.8e-13 48.2 0.0 3.6e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EER23955.1 - 3.3e-05 23.4 0.0 0.00013 21.5 0.0 1.9 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EER23955.1 - 0.0018 17.7 0.0 0.0049 16.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EER23955.1 - 0.0075 16.4 0.0 0.038 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER23955.1 - 0.027 14.2 2.2 4.4 7.1 0.1 3.1 2 1 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 EER23955.1 - 0.05 12.5 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EER23955.1 - 0.061 12.4 0.0 0.24 10.5 0.0 1.9 3 0 0 3 3 3 0 KaiC Ribosomal_L16 PF00252.13 EER23957.1 - 3.4e-31 107.7 0.1 5.7e-31 107.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e IncA PF04156.9 EER23958.1 - 0.00021 20.9 6.6 0.00021 20.9 4.6 2.5 3 0 0 3 3 3 1 IncA protein DUF948 PF06103.6 EER23958.1 - 0.0045 16.8 1.2 0.0045 16.8 0.8 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) DUF2536 PF10750.4 EER23958.1 - 0.0059 16.1 0.1 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2536) YwqJ-deaminase PF14431.1 EER23958.1 - 0.099 12.4 0.8 0.24 11.2 0.5 1.7 1 0 0 1 1 1 0 YwqJ-like deaminase DUF1515 PF07439.6 EER23958.1 - 2.9 7.7 8.7 1.6 8.5 2.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TPR_MLP1_2 PF07926.7 EER23958.1 - 3.6 7.3 25.1 0.033 13.9 9.4 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 EER23958.1 - 6.5 6.7 20.7 0.13 12.2 7.4 3.2 1 1 2 3 3 3 0 FlxA-like protein Clat_adaptor_s PF01217.15 EER23959.1 - 1.2e-12 47.7 0.0 2e-11 43.7 0.1 2.0 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Homeobox_KN PF05920.6 EER23959.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Homeobox KN domain FbpA PF05833.6 EER23960.1 - 9e-37 126.6 13.2 9e-37 126.6 9.1 2.2 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 EER23960.1 - 1.8e-31 108.0 0.0 1.8e-31 108.0 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EER23960.1 - 1.3e-16 60.2 0.0 2.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Sua5_yciO_yrdC PF01300.13 EER23961.1 - 9.4e-57 191.1 0.0 1.6e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EER23961.1 - 6e-25 87.7 0.0 2.3e-24 85.8 0.0 1.9 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding APH PF01636.18 EER23962.1 - 0.0099 15.6 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EER23963.1 - 4.1e-06 26.1 0.0 9.2e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EER23963.1 - 0.0053 16.5 0.1 0.0053 16.5 0.1 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Spore_coat_CotO PF14153.1 EER23963.1 - 0.032 13.6 6.0 0.049 13.0 4.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO OmpH PF03938.9 EER23963.1 - 0.056 13.3 10.1 0.31 10.9 7.4 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SPX PF03105.14 EER23963.1 - 0.1 12.3 3.7 0.16 11.7 2.5 1.4 1 0 0 1 1 1 0 SPX domain ARGLU PF15346.1 EER23963.1 - 0.49 10.1 41.8 1 9.1 29.0 1.5 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 Mnd1 PF03962.10 EER23963.1 - 0.8 9.3 15.0 1.7 8.2 10.4 1.5 1 0 0 1 1 1 0 Mnd1 family CAF-1_p150 PF11600.3 EER23963.1 - 6.6 6.0 44.2 12 5.2 30.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal 2Fe-2S_thioredx PF01257.14 EER23965.1 - 2.4e-59 199.1 0.1 3.1e-59 198.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SNF2_N PF00176.18 EER23966.1 - 2.2e-22 79.2 0.0 8.1e-15 54.3 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EER23966.1 - 7.6e-18 64.7 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.26 EER23966.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CSTF2_hinge PF14327.1 EER23967.1 - 1.4e-29 102.0 1.9 1.4e-29 102.0 1.3 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EER23967.1 - 3.6e-19 68.1 0.0 5.6e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EER23967.1 - 1.9e-17 62.2 10.3 1.9e-17 62.2 7.1 2.0 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 EER23967.1 - 1.5e-16 60.1 0.0 2.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER23967.1 - 5.3e-08 32.5 0.0 7.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EER23967.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 Band_7 PF01145.20 EER23968.1 - 9.6e-24 84.2 2.3 1.6e-23 83.5 1.6 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 EER23968.1 - 0.0091 15.2 0.4 0.012 14.8 0.3 1.3 1 0 0 1 1 1 1 MraW methylase family Ferritin_2 PF13668.1 EER23969.1 - 3.3e-39 133.9 0.0 4.3e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF455 PF04305.9 EER23969.1 - 0.006 15.8 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Ank_2 PF12796.2 EER23970.1 - 3.1e-06 27.4 0.0 0.061 13.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) MCM PF00493.18 EER23971.1 - 3.2e-140 466.6 0.0 4.5e-140 466.1 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EER23971.1 - 3.6e-24 85.5 0.0 2e-23 83.1 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EER23971.1 - 6.2e-06 25.5 0.0 0.00019 20.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EER23971.1 - 4e-05 23.3 0.0 0.00015 21.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EER23971.1 - 0.0018 17.9 0.0 0.0051 16.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EER23971.1 - 0.07 12.6 0.1 6 6.3 0.0 3.3 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA_32 PF13654.1 EER23971.1 - 0.1 11.2 6.6 0.023 13.3 0.3 2.4 3 0 0 3 3 3 0 AAA domain VTC PF09359.5 EER23972.1 - 2.7e-102 341.6 0.4 3.8e-102 341.1 0.3 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EER23972.1 - 9.8e-26 91.1 12.3 5.4e-24 85.4 5.7 3.0 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EER23972.1 - 1.5e-09 37.9 4.9 1.5e-09 37.9 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Ribophorin_I PF04597.9 EER23973.1 - 5.4e-146 486.4 0.0 6.2e-146 486.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I Indigoidine_A PF04227.7 EER23974.1 - 5.7e-111 370.4 1.3 3.7e-104 348.0 0.1 2.3 1 1 1 2 2 2 2 Indigoidine synthase A like protein PfkB PF00294.19 EER23974.1 - 7.4e-13 48.2 0.3 1.4e-06 27.6 0.0 3.0 3 0 0 3 3 3 2 pfkB family carbohydrate kinase SnoaL_2 PF12680.2 EER23975.1 - 1.5e-05 25.3 0.1 3.8e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain SnoaL PF07366.7 EER23975.1 - 0.001 18.6 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DUF3880 PF12996.2 EER23975.1 - 0.028 14.3 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 DUF based on E. rectale Gene description (DUF3880) DUF221 PF02714.10 EER23976.1 - 1.5e-105 352.6 30.4 1.5e-105 352.6 21.1 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EER23976.1 - 2.1e-45 154.0 0.4 2.1e-45 154.0 0.3 3.9 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EER23976.1 - 2.1e-12 46.7 1.3 3.9e-12 45.8 0.0 2.1 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EER23976.1 - 7.7e-09 35.9 9.5 0.00032 21.1 0.4 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4463) Flavokinase PF01687.12 EER23977.1 - 1.1e-33 115.8 0.0 3.7e-20 72.0 0.0 2.0 2 0 0 2 2 2 2 Riboflavin kinase PAS PF00989.19 EER23979.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold MFS_1 PF07690.11 EER23980.1 - 9.8e-39 133.0 42.3 9.8e-39 133.0 29.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER23980.1 - 2.2e-05 22.8 3.5 2.2e-05 22.8 2.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pex24p PF06398.6 EER23980.1 - 0.66 8.7 5.2 3.6 6.2 3.6 2.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin Rad21_Rec8_N PF04825.8 EER23981.1 - 5.4e-39 132.5 0.0 1.1e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EER23981.1 - 1.7e-07 30.3 0.1 3.7e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EER23981.1 - 0.023 14.2 0.0 0.087 12.3 0.0 1.8 2 0 0 2 2 2 0 ScpA/B protein E1-E2_ATPase PF00122.15 EER23982.1 - 4.3e-79 264.7 0.1 7.7e-79 263.9 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EER23982.1 - 3.1e-45 153.9 3.5 5.2e-45 153.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EER23982.1 - 4.4e-31 108.9 0.0 3.1e-29 102.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EER23982.1 - 4.6e-23 80.4 0.0 1.4e-22 78.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EER23982.1 - 1.4e-15 58.0 0.0 3.2e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER23982.1 - 1.5e-13 50.4 0.0 3.1e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EER23982.1 - 2.4e-05 24.0 1.3 0.00019 21.1 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ammonium_transp PF00909.16 EER23983.1 - 8.9e-116 386.6 30.9 1e-115 386.4 21.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family COG4 PF08318.7 EER23984.1 - 2e-100 335.8 0.0 2.5e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein SIR2 PF02146.12 EER23985.1 - 3e-56 189.9 0.0 5.1e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 Sir2 family T2SF PF00482.18 EER23985.1 - 0.15 11.9 0.2 11 5.9 0.0 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Hexokinase_2 PF03727.11 EER23986.1 - 4.9e-87 291.1 0.0 6.6e-87 290.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EER23986.1 - 1.9e-76 255.9 0.0 2.5e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase DUF2587 PF10759.4 EER23986.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) WD40 PF00400.27 EER23987.1 - 0.00019 21.2 5.3 0.16 11.8 0.0 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EER23987.1 - 0.072 11.8 0.0 0.3 9.7 0.0 2.0 3 0 0 3 3 3 0 Nup133 N terminal like Corona_nucleoca PF00937.13 EER23987.1 - 0.47 9.3 4.7 0.75 8.6 3.2 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF3661 PF12400.3 EER23988.1 - 3.7e-40 136.9 3.7 5.2e-40 136.5 2.6 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein RRM_1 PF00076.17 EER23989.1 - 3.2e-17 61.9 1.0 1.6e-07 30.8 0.0 2.7 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER23989.1 - 1.8e-12 47.0 0.2 3.1e-11 43.1 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER23989.1 - 1.3e-07 31.3 0.4 6.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) JmjC PF02373.17 EER23990.1 - 1.4e-09 38.1 0.1 5.6e-09 36.2 0.1 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EER23990.1 - 7.9e-09 35.0 4.6 7.9e-09 35.0 3.2 2.7 3 0 0 3 3 3 1 PHD-finger Cupin_8 PF13621.1 EER23990.1 - 2.9e-08 33.5 0.0 6.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.1 EER23990.1 - 0.022 14.0 5.1 0.03 13.6 2.1 2.4 2 0 0 2 2 2 0 PHD-finger Dickkopf_N PF04706.7 EER23990.1 - 0.075 13.2 10.7 1.8 8.7 2.0 3.1 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 EER23990.1 - 8.9 6.3 30.4 0.14 12.0 3.7 3.0 3 1 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EER23991.1 - 9.4e-38 127.6 0.3 6e-18 64.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER23991.1 - 2.9e-29 100.8 0.1 1.9e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER23991.1 - 3.6e-15 55.5 0.1 1.9e-06 27.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EER23991.1 - 0.0085 15.9 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif PAT1 PF09770.4 EER23992.1 - 8.6 4.4 9.9 9.3 4.3 6.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RabGAP-TBC PF00566.13 EER23993.1 - 9.9e-50 168.9 0.0 2.5e-49 167.6 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RrnaAD PF00398.15 EER23994.1 - 9.5e-58 195.2 0.0 1.2e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EER23994.1 - 3.8e-10 39.8 0.0 6.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER23994.1 - 8.2e-07 29.5 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER23994.1 - 9.2e-05 22.8 0.0 0.00017 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER23994.1 - 0.00019 20.8 0.0 0.0003 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EER23994.1 - 0.00022 20.8 0.0 0.00033 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EER23994.1 - 0.00028 20.4 0.0 0.00041 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EER23994.1 - 0.00064 18.8 0.0 0.00095 18.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EER23994.1 - 0.00065 20.1 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER23994.1 - 0.0022 17.7 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EER23994.1 - 0.0079 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 EER23994.1 - 0.014 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.12 EER23994.1 - 0.017 14.1 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EER23994.1 - 0.047 12.7 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EER23994.1 - 0.09 13.1 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EER23994.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRP1_N PF06424.7 EER23995.1 - 1.1e-54 184.3 6.2 3e-54 182.9 4.3 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EER23995.1 - 2e-27 93.1 32.4 8.9e-05 22.7 0.4 13.6 4 3 10 14 14 14 10 Tetratricopeptide repeat TPR_19 PF14559.1 EER23995.1 - 1.5e-23 82.9 12.8 1.1e-06 28.8 1.3 9.5 6 2 2 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EER23995.1 - 3.1e-22 78.6 22.2 3.5e-05 24.3 2.6 8.8 7 1 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EER23995.1 - 4.1e-12 45.0 6.3 0.19 11.7 0.0 8.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EER23995.1 - 1e-11 44.3 10.6 0.0073 15.9 0.0 8.2 5 4 4 9 9 9 5 TPR repeat TPR_15 PF13429.1 EER23995.1 - 5.4e-06 25.6 22.0 9.4e-05 21.6 5.8 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EER23995.1 - 1.3e-05 24.6 0.5 4.7 7.2 0.0 7.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER23995.1 - 3e-05 23.4 2.0 0.68 9.6 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EER23995.1 - 5e-05 23.1 7.6 47 4.5 0.0 8.7 10 1 1 11 11 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 EER23995.1 - 0.013 15.4 7.5 6 6.8 0.0 6.9 5 1 2 8 8 8 0 Tetratricopeptide repeat Cutinase PF01083.17 EER23995.1 - 0.05 13.3 0.0 0.36 10.5 0.0 2.3 1 1 1 2 2 2 0 Cutinase DUF3808 PF10300.4 EER23995.1 - 0.11 10.9 4.4 5.5 5.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) SAGA-Tad1 PF12767.2 EER23996.1 - 3.5e-59 200.5 0.0 5e-59 200.0 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit FUSC_2 PF13515.1 EER23997.1 - 1.4e-30 105.8 8.8 1.4e-30 105.8 6.1 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EER23997.1 - 2.4e-07 29.7 7.6 0.0092 14.6 0.0 3.5 3 1 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 EER23997.1 - 4.3e-06 25.4 8.3 4.3e-06 25.4 5.8 2.8 3 1 0 3 3 3 1 Fusaric acid resistance protein family DUF2421 PF10334.4 EER23997.1 - 0.00029 20.5 0.6 0.0011 18.6 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) IFT20 PF14931.1 EER23997.1 - 0.064 13.1 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 MFS_1 PF07690.11 EER23998.1 - 3.7e-28 98.2 30.9 3.9e-27 94.8 21.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EER23998.1 - 8e-21 73.8 7.0 9.2e-21 73.6 4.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3784 PF12650.2 EER23998.1 - 0.35 10.8 4.8 0.6 10.0 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) PRA1 PF03208.14 EER23998.1 - 0.62 9.3 4.2 0.67 9.2 0.4 2.7 3 0 0 3 3 3 0 PRA1 family protein AzlD PF05437.7 EER23998.1 - 1.3 8.9 10.9 0.058 13.3 1.4 3.0 4 0 0 4 4 4 0 Branched-chain amino acid transport protein (AzlD) Polysacc_synt_C PF14667.1 EER23998.1 - 9.4 6.0 20.6 0.35 10.6 4.1 3.6 3 1 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain WD40 PF00400.27 EER23999.1 - 2.5e-54 179.3 20.6 1.5e-09 37.3 0.2 10.5 10 0 0 10 10 10 9 WD domain, G-beta repeat eIF2A PF08662.6 EER23999.1 - 9.3e-05 22.2 1.5 0.9 9.2 0.1 4.9 4 2 2 6 6 6 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EER23999.1 - 0.00034 20.2 0.7 11 5.7 0.0 5.1 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EER23999.1 - 0.012 13.8 0.0 0.022 12.8 0.0 1.6 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Nbas_N PF15492.1 EER23999.1 - 0.018 14.1 1.3 28 3.6 0.1 4.0 4 1 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 EER23999.1 - 0.029 14.6 8.2 5.5 7.3 0.3 6.4 6 0 0 6 6 6 0 PQQ-like domain IKI3 PF04762.7 EER23999.1 - 0.2 9.4 0.0 3.6 5.2 0.0 2.3 2 1 0 2 2 2 0 IKI3 family IRF PF00605.12 EER23999.1 - 0.35 10.6 2.1 0.56 10.0 0.1 2.2 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor Ribosomal_S18 PF01084.15 EER24000.1 - 5.9e-16 58.0 0.5 1.2e-15 57.0 0.0 1.8 2 1 1 3 3 3 1 Ribosomal protein S18 PPR_2 PF13041.1 EER24001.1 - 1.8e-13 50.2 0.4 0.18 11.7 0.0 7.1 5 3 2 7 7 7 5 PPR repeat family PPR_3 PF13812.1 EER24001.1 - 5.3e-12 45.0 2.1 0.0014 18.7 0.0 7.9 8 0 0 8 8 8 2 Pentatricopeptide repeat domain PPR PF01535.15 EER24001.1 - 4.8e-11 41.8 6.3 0.037 13.9 0.1 7.6 8 0 0 8 8 8 4 PPR repeat TPR_14 PF13428.1 EER24001.1 - 0.0083 16.6 4.7 10 7.0 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Glyco_hydro_67C PF07477.7 EER24001.1 - 0.0086 15.5 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus ELFV_dehydrog PF00208.16 EER24002.1 - 2.2e-56 191.1 0.0 4.2e-56 190.2 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EER24002.1 - 5.7e-18 63.8 0.1 7.9e-15 53.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EER24002.1 - 0.023 14.2 0.0 0.066 12.8 0.0 1.7 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain TFIIIC_sub6 PF10419.4 EER24003.1 - 4.8e-14 51.5 0.0 9.5e-14 50.5 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit DUF946 PF06101.6 EER24004.1 - 7.4e-13 47.3 0.3 1.2e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) TRP PF06011.7 EER24005.1 - 4.7e-137 457.1 6.6 5.7e-137 456.8 4.6 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EER24005.1 - 5.6e-36 123.6 0.1 9e-36 123.0 0.1 1.3 1 0 0 1 1 1 1 ML-like domain ODV-E18 PF10717.4 EER24005.1 - 0.23 10.9 1.1 4 6.9 0.2 2.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF2681 PF10883.3 EER24005.1 - 0.64 10.2 0.0 0.64 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) IncA PF04156.9 EER24005.1 - 2.1 7.9 12.7 2.3 7.7 0.0 3.4 3 0 0 3 3 3 0 IncA protein ATG22 PF11700.3 EER24006.1 - 6.6e-210 697.5 20.2 7.5e-210 697.3 14.0 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EER24006.1 - 2.4e-08 33.0 47.9 2e-05 23.4 3.1 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EER24006.1 - 2.6e-05 22.7 31.3 0.0098 14.3 5.9 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EER24006.1 - 0.0026 17.4 3.6 0.27 11.0 0.1 3.3 3 0 0 3 3 3 2 MFS_1 like family Actin PF00022.14 EER24007.1 - 3.7e-137 456.9 0.0 4.2e-137 456.7 0.0 1.0 1 0 0 1 1 1 1 Actin Hep_59 PF07052.6 EER24008.1 - 1.1e-22 80.2 2.6 1.5e-22 79.9 0.1 2.3 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF2300 PF10062.4 EER24008.1 - 0.03 14.0 0.1 0.055 13.2 0.1 1.4 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) Methyltransf_16 PF10294.4 EER24009.1 - 2.4e-45 154.0 0.0 3.3e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EER24009.1 - 0.014 15.9 0.0 0.03 14.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EER24009.1 - 0.055 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EER24009.1 - 0.083 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mpp10 PF04006.7 EER24010.1 - 1.3e-100 337.5 39.4 2e-100 336.9 27.3 1.3 1 0 0 1 1 1 1 Mpp10 protein AhpC-TSA PF00578.16 EER24012.1 - 4.2e-24 84.5 0.0 6.6e-24 83.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EER24012.1 - 5e-15 55.3 0.0 6.6e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EER24012.1 - 4.8e-05 23.2 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme CH PF00307.26 EER24013.1 - 1.8e-66 221.0 0.0 1.2e-19 70.3 0.4 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EER24013.1 - 1.2e-06 28.5 0.4 2.8e-05 24.1 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EER24013.1 - 2.2e-05 24.0 0.0 1.5 8.5 0.0 4.0 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_1 PF00036.27 EER24013.1 - 0.0043 16.2 0.4 0.99 8.8 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EER24013.1 - 0.021 14.6 2.3 0.19 11.7 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain HD PF01966.17 EER24014.1 - 8.1e-06 25.8 0.0 1.2e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 HD domain DSPc PF00782.15 EER24015.1 - 1.3e-25 89.4 0.0 1.9e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EER24015.1 - 0.00093 18.6 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PC4 PF02229.11 EER24016.1 - 3.3e-22 77.4 0.1 5.4e-22 76.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.9 EER24017.1 - 1.1e-203 677.3 0.0 1.5e-203 676.8 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EER24017.1 - 7.6e-96 320.6 0.2 1.7e-95 319.4 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EER24017.1 - 2e-58 196.7 0.8 1.3e-56 190.8 0.0 2.8 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region NAD_Gly3P_dh_N PF01210.18 EER24017.1 - 0.15 11.7 0.0 9.7 5.9 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MIT PF04212.13 EER24018.1 - 1.5e-11 44.0 0.8 4.8e-11 42.3 0.2 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Totivirus_coat PF05518.6 EER24018.1 - 3.3 5.4 11.9 5.7 4.6 8.3 1.3 1 0 0 1 1 1 0 Totivirus coat protein PRESAN PF09687.5 EER24019.1 - 0.021 14.8 1.0 0.083 12.9 0.1 2.3 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Na_Ca_ex PF01699.19 EER24020.1 - 1.4e-20 73.3 20.5 1.6e-13 50.4 1.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4131 PF13567.1 EER24020.1 - 0.27 10.6 8.4 17 4.7 3.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) PALP PF00291.20 EER24021.1 - 5.3e-59 199.9 0.1 8.5e-59 199.2 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EER24021.1 - 1.5e-07 31.1 0.0 3.2e-06 26.8 0.0 2.6 3 0 0 3 3 3 1 CBS domain SRPRB PF09439.5 EER24022.1 - 6.6e-23 80.8 0.3 6.4e-18 64.6 0.1 2.5 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.16 EER24022.1 - 0.00011 21.4 0.2 0.0011 18.2 0.1 2.4 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.1 EER24022.1 - 0.0016 18.4 0.4 0.0073 16.3 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EER24022.1 - 0.0039 16.3 0.0 0.0081 15.3 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 EER24022.1 - 0.0083 16.3 0.5 0.029 14.5 0.3 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER24022.1 - 0.016 15.3 0.1 0.042 13.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EER24022.1 - 0.017 14.6 0.1 3.1 7.2 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EER24022.1 - 0.057 14.2 0.1 0.2 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EER24022.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EER24022.1 - 0.078 12.4 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.9 EER24022.1 - 0.12 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EER24022.1 - 0.13 12.5 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EER24022.1 - 0.15 11.5 0.0 0.35 10.3 0.0 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GPI-anchored PF10342.4 EER24023.1 - 4.6e-13 49.4 0.0 8.6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 EER24023.1 - 2.8e-08 34.0 0.9 5.3e-08 33.1 0.6 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.23 EER24024.1 - 8.1e-42 143.4 1.5 1.3e-41 142.7 1.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EER24024.1 - 3e-17 62.1 0.5 2.1e-16 59.4 0.0 2.3 2 0 0 2 2 2 1 PUA domain Nucleotid_trans PF03407.11 EER24024.1 - 0.2 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Peptidase_M76 PF09768.4 EER24025.1 - 6.2e-72 240.6 5.9 8.3e-72 240.2 4.1 1.2 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.1 EER24025.1 - 0.025 14.0 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Peptidase_M13 PF01431.16 EER24025.1 - 0.045 12.9 0.1 0.066 12.3 0.1 1.3 1 0 0 1 1 1 0 Peptidase family M13 SprT-like PF10263.4 EER24025.1 - 0.079 12.6 10.2 0.015 14.9 3.6 2.3 1 1 1 2 2 2 0 SprT-like family Peptidase_M91 PF14891.1 EER24025.1 - 0.084 12.9 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Effector protein Pkinase PF00069.20 EER24026.1 - 4.6e-69 232.4 0.0 5.6e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24026.1 - 7.3e-41 139.9 0.0 9.5e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER24026.1 - 1.2e-05 24.4 0.0 2.8e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EER24026.1 - 0.00014 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EER24026.1 - 0.019 14.2 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EER24026.1 - 0.063 12.9 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 EER24027.1 - 1.7e-80 268.5 0.0 2.1e-80 268.2 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Ubiq_cyt_C_chap PF03981.7 EER24028.1 - 4.2e-36 123.8 0.0 5.2e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Peptidase_M24 PF00557.19 EER24030.1 - 1.2e-53 181.7 0.0 3.8e-53 180.1 0.0 1.8 2 0 0 2 2 2 1 Metallopeptidase family M24 AMP_N PF05195.11 EER24030.1 - 1.3e-25 89.3 0.0 4.9e-25 87.4 0.0 1.9 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF2183 PF09949.4 EER24032.1 - 1e-19 70.2 0.1 2.2e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Cyclin PF08613.6 EER24033.1 - 2.2e-32 112.5 0.0 2.9e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EER24033.1 - 0.0065 16.0 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.2 EER24034.1 - 7.3e-43 144.8 0.0 3e-17 62.7 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EER24034.1 - 7e-35 117.1 0.5 4.3e-09 35.7 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EER24034.1 - 3.9e-29 100.0 2.0 3e-09 36.8 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER24034.1 - 5.4e-25 84.9 1.2 7e-08 31.9 0.0 6.0 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EER24034.1 - 5.1e-24 84.2 4.8 2.1e-10 40.8 0.1 5.0 3 1 3 6 6 6 5 Ankyrin repeats (many copies) zf-DHHC PF01529.15 EER24034.1 - 6.3e-17 61.5 11.5 3.5e-15 55.8 3.1 2.9 3 0 0 3 3 3 2 DHHC palmitoyltransferase K_oxygenase PF13434.1 EER24035.1 - 2.3e-108 362.1 0.0 2.7e-108 361.9 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EER24035.1 - 1.2e-09 38.5 0.0 4.2e-08 33.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER24035.1 - 5.4e-09 36.0 0.0 5e-07 29.6 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EER24035.1 - 4.2e-07 30.0 0.0 0.00012 22.0 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DUF4147 PF13660.1 EER24035.1 - 0.063 12.3 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Lycopene_cycl PF05834.7 EER24035.1 - 0.15 10.9 0.0 4.9 5.9 0.0 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein AMP-binding PF00501.23 EER24036.1 - 8.9e-249 824.8 0.0 9e-86 287.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EER24036.1 - 5.1e-163 541.0 0.0 1.1e-37 129.4 0.0 7.0 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EER24036.1 - 1.5e-58 194.9 15.6 6.3e-10 39.1 0.2 6.9 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EER24036.1 - 6.9e-18 65.3 0.0 1.4e-07 32.3 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EER24036.1 - 0.00074 19.7 2.8 1.1 9.6 0.0 4.5 4 0 0 4 4 4 2 HxxPF-repeated domain Aldolase PF01081.14 EER24036.1 - 0.11 11.6 0.2 16 4.6 0.0 2.5 2 0 0 2 2 2 0 KDPG and KHG aldolase Pkinase PF00069.20 EER24037.1 - 8.5e-40 136.5 0.0 1.7e-39 135.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24037.1 - 6e-23 81.2 0.0 9e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER24037.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family OB_NTP_bind PF07717.11 EER24038.1 - 5.1e-30 103.6 0.0 1.4e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EER24038.1 - 5e-25 87.4 0.0 5e-25 87.4 0.0 2.9 4 0 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EER24038.1 - 2.6e-12 46.4 0.0 6.3e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EER24038.1 - 1.1e-05 25.0 0.2 3.1e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EER24038.1 - 3.6e-05 23.9 0.1 0.00016 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EER24038.1 - 5.2e-05 22.2 0.0 0.00011 21.2 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EER24038.1 - 0.0081 15.6 0.3 0.019 14.3 0.2 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Sigma54_activ_2 PF14532.1 EER24038.1 - 0.024 14.6 0.0 0.077 13.0 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 EER24038.1 - 0.058 13.7 0.1 0.058 13.7 0.1 3.7 1 1 2 3 3 1 0 AAA domain ResIII PF04851.10 EER24038.1 - 0.071 12.9 2.1 0.67 9.7 0.0 3.1 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EER24038.1 - 1.5 9.1 5.7 0.27 11.5 0.1 2.6 1 1 1 2 2 2 0 ABC transporter AAA_33 PF13671.1 EER24038.1 - 5.9 6.7 9.2 2.4 8.0 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EER24039.1 - 7.6e-12 45.5 0.0 1.2e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EER24039.1 - 0.006 15.6 0.0 0.0086 15.1 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EER24039.1 - 0.055 14.2 0.0 0.08 13.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 EER24040.1 - 2.5e-21 75.9 0.0 7e-21 74.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24040.1 - 1.6e-09 37.2 0.0 0.0014 17.7 0.0 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase Kinase-like PF14531.1 EER24040.1 - 0.0077 15.2 0.0 2.2 7.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Cyt-b5 PF00173.23 EER24041.1 - 2.8e-19 68.7 0.1 3.1e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 EER24041.1 - 0.0097 15.8 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H DUF4291 PF14124.1 EER24042.1 - 3.3e-73 245.1 0.1 3.7e-73 245.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Mcp5_PH PF12814.2 EER24043.1 - 2e-46 156.8 0.1 5.5e-46 155.4 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology CENP-F_leu_zip PF10473.4 EER24043.1 - 0.0018 18.1 19.1 0.0035 17.2 13.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EER24043.1 - 0.015 15.0 22.1 0.032 13.9 5.4 2.6 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.10 EER24043.1 - 0.19 11.7 16.6 0.4 10.6 11.5 1.4 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.1 EER24043.1 - 1.1 7.5 10.1 1.9 6.8 7.0 1.2 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EER24043.1 - 3.7 7.1 24.6 0.36 10.3 5.5 2.3 1 1 1 2 2 2 0 IncA protein LMBR1 PF04791.11 EER24043.1 - 7.9 4.9 4.0 12 4.3 2.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4200 PF13863.1 EER24043.1 - 9.8 6.1 17.5 22 5.0 12.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) GST_C_2 PF13410.1 EER24044.1 - 7.5e-17 60.9 0.1 1.2e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EER24044.1 - 4.6e-11 42.5 0.0 8.7e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EER24044.1 - 9.7e-08 32.4 0.0 1.8e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EER24044.1 - 1.2e-07 31.5 0.0 2.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ras PF00071.17 EER24045.1 - 3.2e-50 169.6 0.1 2.5e-49 166.8 0.1 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EER24045.1 - 2.3e-16 60.3 0.0 7.2e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EER24045.1 - 0.00072 18.8 0.0 0.0027 16.9 0.1 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EER24045.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EER24045.1 - 0.038 13.1 0.1 0.068 12.2 0.1 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EER24045.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.23 EER24046.1 - 1e-81 274.4 0.0 1.2e-81 274.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER24046.1 - 7.1e-15 55.7 0.0 1.7e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EER24047.1 - 2.3e-35 121.9 29.0 3e-35 121.5 20.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Flocculin_t3 PF13928.1 EER24048.1 - 0.018 15.1 10.3 0.018 15.1 7.1 3.2 2 1 1 3 3 3 0 Flocculin type 3 repeat SHMT PF00464.14 EER24049.1 - 1.2e-198 659.4 0.0 1.4e-198 659.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MOSC PF03473.12 EER24050.1 - 7.8e-17 60.9 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EER24050.1 - 1.8e-16 59.9 0.0 3.2e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Patatin PF01734.17 EER24051.1 - 2.9e-23 82.8 0.0 7.4e-23 81.5 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Mg_trans_NIPA PF05653.9 EER24053.1 - 1.5e-87 293.3 25.5 2.1e-87 292.8 17.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EER24053.1 - 1.3e-05 25.3 6.2 1.3e-05 25.3 4.3 3.2 1 1 2 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EER24053.1 - 3.8e-05 23.7 6.3 3.8e-05 23.7 4.3 2.8 2 1 0 2 2 2 1 EamA-like transporter family Zn_clus PF00172.13 EER24054.1 - 8.4e-10 38.4 11.6 1.5e-09 37.5 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EER24054.1 - 0.69 9.4 6.0 1.7 8.2 4.2 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF3554 PF12074.3 EER24056.1 - 4.6e-77 259.7 4.8 8.9e-77 258.7 1.4 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 EER24056.1 - 2.1e-59 199.5 7.9 2.1e-59 199.5 5.5 2.1 2 0 0 2 2 2 1 Ribosomal protein L19e HEAT_2 PF13646.1 EER24056.1 - 4.7e-35 119.7 51.0 3.5e-10 40.0 0.0 15.2 11 2 5 17 17 16 7 HEAT repeats HEAT PF02985.17 EER24056.1 - 5.5e-33 110.0 31.1 0.1 12.7 0.0 20.8 24 0 0 24 24 22 7 HEAT repeat HEAT_EZ PF13513.1 EER24056.1 - 9.3e-25 86.4 58.4 3.7e-05 24.0 0.0 23.9 17 4 11 28 28 25 7 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EER24056.1 - 1.1e-13 51.3 0.0 0.42 11.0 0.0 8.8 7 2 2 9 9 8 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EER24056.1 - 1.3e-08 34.8 0.1 1.1 9.0 0.0 7.0 6 2 1 7 7 7 3 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EER24056.1 - 4e-07 30.0 3.5 1.3 8.9 0.0 6.9 6 1 0 6 6 6 2 Parkin co-regulated protein Ipi1_N PF12333.3 EER24056.1 - 3.4e-05 23.7 0.8 5.8 6.9 0.0 6.6 6 1 0 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Cohesin_HEAT PF12765.2 EER24056.1 - 0.012 15.5 5.4 1.7 8.7 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion GSHPx PF00255.14 EER24056.1 - 0.3 10.4 0.0 0.64 9.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione peroxidase HA2 PF04408.18 EER24057.1 - 1.9e-20 72.7 0.1 6e-20 71.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EER24057.1 - 9.4e-10 38.2 0.7 0.00038 20.2 0.2 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EER24057.1 - 1e-09 38.1 0.0 3.1e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EER24057.1 - 1.3e-06 28.5 0.5 4.1e-06 26.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain ACPS PF01648.15 EER24057.1 - 0.015 15.1 0.0 0.051 13.3 0.0 1.9 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DrrA_P4M PF14860.1 EER24057.1 - 0.034 13.9 0.2 0.081 12.6 0.2 1.6 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain FtsK_SpoIIIE PF01580.13 EER24057.1 - 0.047 13.1 0.1 0.45 9.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RuvA_C PF07499.8 EER24057.1 - 0.11 12.6 0.9 0.82 9.8 0.0 2.7 3 0 0 3 3 3 0 RuvA, C-terminal domain KilA-N PF04383.8 EER24058.1 - 0.00017 21.1 0.0 0.0028 17.2 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain BRCT PF00533.21 EER24059.1 - 5.5e-07 29.6 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EER24059.1 - 0.0005 19.8 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain adh_short PF00106.20 EER24060.1 - 9.3e-28 97.2 0.5 2.3e-27 95.9 0.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER24060.1 - 5.2e-12 46.0 0.0 7.3e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER24060.1 - 4.7e-11 42.6 1.1 1e-09 38.3 0.7 2.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EER24060.1 - 1.9e-05 24.7 0.0 0.00022 21.2 0.0 2.5 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EER24060.1 - 0.025 14.0 0.0 0.065 12.6 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EER24060.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family V_ATPase_I PF01496.14 EER24061.1 - 0.22 9.3 9.7 0.39 8.5 6.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XhlA PF10779.4 EER24061.1 - 3 7.8 5.6 25 4.8 3.9 2.7 1 0 0 1 1 1 0 Haemolysin XhlA CorA PF01544.13 EER24062.1 - 2.8e-40 138.1 0.1 4.7e-40 137.4 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Vac7 PF12751.2 EER24063.1 - 6.6e-165 548.6 9.1 6.6e-165 548.6 6.3 2.7 2 1 0 2 2 2 1 Vacuolar segregation subunit 7 DUF3824 PF12868.2 EER24064.1 - 3.9e-34 118.5 75.1 4.1e-27 95.7 18.8 8.0 4 3 4 8 8 8 5 Domain of unknwon function (DUF3824) DUF2613 PF11021.3 EER24064.1 - 0.063 12.9 0.1 0.063 12.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) Ribosomal_60s PF00428.14 EER24064.1 - 6.7 7.1 19.2 1.8 9.0 2.4 3.3 3 0 0 3 3 3 0 60s Acidic ribosomal protein Ribosomal_L44 PF00935.14 EER24065.1 - 1.3e-34 118.0 11.4 1.9e-34 117.4 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.18 EER24066.1 - 6.6e-25 86.3 0.0 7.3e-25 86.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EER24066.1 - 8.1e-17 60.6 0.1 8.9e-17 60.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EER24066.1 - 0.00025 21.2 0.0 0.00094 19.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Elongin_A PF06881.6 EER24067.1 - 2.4e-23 82.6 0.1 4.2e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Sugar_tr PF00083.19 EER24069.1 - 8.3e-70 235.5 23.0 8.6e-68 228.9 16.0 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER24069.1 - 9.8e-06 24.5 35.1 1.9e-05 23.5 21.0 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EER24069.1 - 0.0011 17.4 8.1 0.0011 17.4 5.6 3.9 2 2 1 4 4 4 2 MFS/sugar transport protein EBP PF05241.7 EER24069.1 - 0.69 8.8 8.6 0.061 12.3 1.6 2.1 2 0 0 2 2 2 0 Emopamil binding protein Hemerythrin PF01814.18 EER24070.1 - 1.4e-11 44.6 5.3 1.7e-11 44.4 3.7 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Band_7 PF01145.20 EER24071.1 - 1.3e-16 61.0 0.1 1.3e-16 61.0 0.1 2.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family TBCA PF02970.11 EER24073.1 - 3.2e-11 43.1 13.3 9.7e-10 38.3 7.1 2.6 1 1 1 2 2 2 2 Tubulin binding cofactor A Ada3 PF10198.4 EER24073.1 - 0.0064 16.2 4.3 0.0077 15.9 3.0 1.1 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 DUF1409 PF07197.7 EER24073.1 - 0.11 12.5 0.3 0.11 12.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) OmpH PF03938.9 EER24073.1 - 0.26 11.2 9.4 0.33 10.8 6.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.4 EER24073.1 - 7.2 6.8 6.5 3.1 8.0 1.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) THOC7 PF05615.8 EER24074.1 - 1e-41 142.4 10.5 1e-41 142.4 7.2 2.2 1 1 1 2 2 2 1 Tho complex subunit 7 Atg14 PF10186.4 EER24074.1 - 0.052 12.4 7.5 0.073 12.0 5.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FUSC PF04632.7 EER24074.1 - 0.077 11.4 5.7 0.1 11.0 3.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA_13 PF13166.1 EER24074.1 - 0.1 11.0 6.9 0.14 10.6 4.8 1.2 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EER24074.1 - 0.12 11.5 0.8 0.18 10.9 0.5 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SSFA2_C PF14723.1 EER24074.1 - 0.35 10.6 3.5 0.7 9.6 2.5 1.5 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF1843 PF08898.5 EER24074.1 - 0.59 10.2 8.3 0.2 11.7 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) zf-C4H2 PF10146.4 EER24074.1 - 0.81 9.6 14.9 0.37 10.7 6.7 2.3 1 1 0 2 2 2 0 Zinc finger-containing protein FlxA PF14282.1 EER24074.1 - 0.86 9.5 8.1 0.99 9.3 2.9 2.6 2 0 0 2 2 2 0 FlxA-like protein DUF342 PF03961.8 EER24074.1 - 1.4 7.2 12.0 4.7 5.5 7.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CDC37_N PF03234.9 EER24074.1 - 2.6 8.3 10.0 0.95 9.7 4.6 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding TMPIT PF07851.8 EER24074.1 - 3.1 6.7 4.5 4.4 6.2 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein SseC PF04888.7 EER24074.1 - 6.8 5.9 8.7 10 5.3 2.9 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family PTR2 PF00854.16 EER24075.1 - 9.9e-47 159.4 9.8 3.6e-26 91.8 1.7 2.5 2 1 1 3 3 3 2 POT family DUF3529 PF12046.3 EER24075.1 - 0.025 13.5 0.1 0.053 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) AA_permease PF00324.16 EER24076.1 - 4.7e-122 407.7 41.1 5.8e-122 407.4 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER24076.1 - 5.7e-41 140.4 43.8 8.7e-41 139.8 30.2 1.3 1 1 0 1 1 1 1 Amino acid permease Malic_M PF03949.10 EER24077.1 - 3e-84 282.5 0.0 3.9e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EER24077.1 - 4.7e-62 208.8 0.0 7.6e-62 208.1 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.1 EER24078.1 - 8.2e-06 25.8 0.1 8.2e-06 25.8 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) GrpE PF01025.14 EER24078.1 - 0.023 14.2 1.6 3.4 7.2 0.5 2.6 2 1 0 2 2 2 0 GrpE TipAS PF07739.8 EER24078.1 - 0.026 14.8 6.0 4.6 7.5 2.3 3.9 3 1 0 3 3 3 0 TipAS antibiotic-recognition domain YtxH PF12732.2 EER24078.1 - 0.54 10.6 8.2 2.4 8.5 1.3 3.2 3 0 0 3 3 3 0 YtxH-like protein DnaJ PF00226.26 EER24079.1 - 3.4e-25 87.5 2.0 6.1e-25 86.7 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EER24079.1 - 4.3e-15 55.5 15.7 7.6e-15 54.7 10.9 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EER24079.1 - 2.4e-10 40.1 0.0 7.1e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EER24079.1 - 0.014 15.0 6.4 0.17 11.6 0.3 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 EER24079.1 - 1.4 9.2 9.0 10 6.4 1.9 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-C3HC4_3 PF13920.1 EER24079.1 - 2.3 7.9 7.5 0.19 11.4 0.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EER24079.1 - 3.7 7.4 13.2 2e+02 1.9 9.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon S4 PF01479.20 EER24080.1 - 8.1e-12 44.3 0.0 1.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EER24080.1 - 0.0011 19.3 2.0 0.0016 18.7 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain MFS_1 PF07690.11 EER24082.1 - 2.6e-33 115.2 28.9 2.6e-33 115.2 20.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OMPdecase PF00215.19 EER24083.1 - 7.1e-76 254.5 0.0 8.1e-76 254.3 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 EER24084.1 - 1.6e-22 79.4 2.7 2e-22 79.1 1.8 1.1 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.14 EER24085.1 - 7e-23 81.2 18.1 1.4e-22 80.2 12.5 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EER24085.1 - 0.0012 18.8 2.4 0.0034 17.4 1.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.27 EER24086.1 - 2.5e-47 157.0 27.0 1.8e-08 33.9 0.8 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EER24086.1 - 0.00044 20.0 0.3 0.21 11.3 0.1 2.6 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Bacteroid_pep PF14406.1 EER24086.1 - 0.17 12.0 0.0 0.43 10.7 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Tmemb_170 PF10190.4 EER24087.1 - 0.00015 21.7 8.4 0.00019 21.4 5.8 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 ICMT PF04140.9 EER24089.1 - 3.3e-25 88.1 0.8 3.3e-25 88.1 0.5 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EER24089.1 - 4e-11 42.9 2.4 4e-11 42.9 1.7 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EER24089.1 - 0.00019 20.7 0.3 0.00036 19.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Hexapep PF00132.19 EER24090.1 - 5.4e-15 54.1 13.0 9.9e-12 43.8 4.6 3.0 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EER24090.1 - 1.9e-14 53.4 0.0 3.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EER24090.1 - 2.9e-12 45.9 12.4 2.2e-11 43.1 3.2 3.0 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF3517 PF12030.3 EER24091.1 - 2.2e-115 384.8 0.1 3.7e-115 384.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 EER24091.1 - 4.2e-47 160.5 0.1 8.1e-47 159.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER24091.1 - 5.9e-20 71.8 0.2 1.4e-19 70.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TGS PF02824.16 EER24091.1 - 0.24 11.2 0.0 0.62 9.9 0.0 1.6 1 0 0 1 1 1 0 TGS domain TrkH PF02386.11 EER24092.1 - 4e-102 341.4 13.4 3e-99 331.9 5.2 2.1 2 0 0 2 2 2 2 Cation transport protein TFIIE_alpha PF02002.12 EER24093.1 - 2.5e-18 65.5 0.0 4.8e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit Malate_DH PF12434.3 EER24093.1 - 0.98 9.1 8.8 0.23 11.1 2.7 2.5 3 0 0 3 3 3 0 Malate dehydrogenase enzyme PseudoU_synth_1 PF01416.15 EER24094.1 - 3.6e-23 81.9 0.0 2.5e-10 40.7 0.0 2.7 2 1 0 2 2 2 2 tRNA pseudouridine synthase Anillin PF08174.6 EER24095.1 - 5e-33 114.0 0.0 1.9e-32 112.2 0.0 2.1 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EER24095.1 - 1e-07 32.0 0.0 3.5e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EER24095.1 - 0.00055 20.1 0.0 0.0018 18.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain NYN_YacP PF05991.6 EER24095.1 - 0.034 13.8 1.4 0.072 12.8 0.1 2.2 2 0 0 2 2 2 0 YacP-like NYN domain DEAD PF00270.24 EER24096.1 - 1.1e-34 119.4 0.1 2.7e-34 118.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER24096.1 - 5.1e-17 61.4 0.0 1.3e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER24096.1 - 0.0028 17.5 0.0 0.01 15.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EER24096.1 - 0.0043 15.8 0.0 0.0081 14.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SET PF00856.23 EER24097.1 - 5.1e-10 39.8 1.2 1.2e-09 38.7 0.0 2.5 2 2 0 2 2 2 1 SET domain Ribosomal_L14 PF00238.14 EER24098.1 - 6.4e-43 145.3 0.9 7.6e-43 145.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TFIIS_C PF01096.13 EER24099.1 - 4.5e-15 54.9 2.9 4.5e-15 54.9 2.0 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EER24099.1 - 1.6e-10 40.4 0.7 1.6e-10 40.4 0.5 2.5 3 0 0 3 3 2 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EER24099.1 - 0.016 15.4 1.6 0.016 15.4 1.1 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar Ogr_Delta PF04606.7 EER24099.1 - 0.052 13.2 1.9 0.052 13.2 1.3 2.3 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger GFA PF04828.9 EER24099.1 - 0.24 11.3 10.5 0.67 9.9 0.0 2.5 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme eIF3g PF12353.3 EER24099.1 - 0.37 10.7 3.4 0.13 12.1 0.4 1.8 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G zf-ribbon_3 PF13248.1 EER24099.1 - 0.46 9.7 8.7 1.1 8.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EER24099.1 - 0.76 9.6 14.4 2.3e+03 -1.5 10.0 2.8 1 1 0 1 1 1 0 Double zinc ribbon C1_4 PF07975.7 EER24099.1 - 0.77 9.8 11.1 0.34 10.9 0.5 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain A2L_zn_ribbon PF08792.5 EER24099.1 - 0.87 9.1 10.2 0.35 10.3 1.0 3.3 3 0 0 3 3 3 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 EER24099.1 - 1.7 8.6 10.6 16 5.5 1.0 3.8 4 0 0 4 4 4 0 Zinc ribbon domain zf-AD PF07776.10 EER24099.1 - 8 6.5 7.9 0.4 10.7 0.1 2.5 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Rotamase PF00639.16 EER24100.1 - 7.1e-23 81.1 0.0 9.7e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EER24100.1 - 7.7e-18 64.8 0.0 9.9e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EER24100.1 - 2.3e-10 40.1 2.5 4.7e-10 39.1 1.8 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EER24100.1 - 6.1e-05 23.6 0.0 7.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain PSP PF04046.11 EER24100.1 - 0.43 10.0 2.6 12 5.4 0.1 3.3 4 0 0 4 4 4 0 PSP WD40 PF00400.27 EER24102.1 - 0.0069 16.2 0.6 0.047 13.5 0.2 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Cas_GSU0053 PF09617.5 EER24102.1 - 0.035 13.9 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) RRM_1 PF00076.17 EER24103.1 - 4.6e-15 54.9 0.0 6.5e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER24103.1 - 7.9e-12 44.9 0.0 1.3e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER24103.1 - 1.7e-08 34.1 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.14 EER24104.1 - 9.6e-56 188.3 0.0 5.2e-44 150.1 0.0 2.2 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EER24104.1 - 5.1e-10 39.1 0.0 3.7e-08 33.1 0.0 2.2 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EER24104.1 - 6.9e-07 28.8 0.0 5.4e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EER24104.1 - 0.0002 20.8 0.0 0.00032 20.1 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EER24104.1 - 0.0014 17.9 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 Putative amidotransferase Peptidase_S51 PF03575.12 EER24104.1 - 0.08 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 ACPS PF01648.15 EER24105.1 - 1.9e-10 40.5 0.0 3.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.16 EER24106.1 - 3.9e-33 113.7 0.0 5.8e-33 113.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase TPR_1 PF00515.23 EER24107.1 - 1.2e-39 132.2 9.2 4.5e-08 32.3 0.0 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 EER24107.1 - 3.6e-37 125.8 17.7 1.8e-12 46.7 1.4 7.8 5 1 4 9 9 9 7 TPR repeat TPR_2 PF07719.12 EER24107.1 - 6.4e-34 113.1 16.3 2.2e-05 24.0 0.0 9.3 10 0 0 10 10 9 6 Tetratricopeptide repeat Apc3 PF12895.2 EER24107.1 - 2.4e-32 110.8 10.7 6.5e-22 77.4 0.1 4.6 4 0 0 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EER24107.1 - 1.2e-26 90.4 0.1 0.014 15.1 0.0 7.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EER24107.1 - 1e-24 86.6 8.9 2.5e-07 31.2 0.0 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EER24107.1 - 8.2e-21 72.6 2.2 0.15 12.7 0.0 9.5 5 1 3 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EER24107.1 - 1.9e-20 72.6 16.0 1.4e-05 24.9 0.0 7.5 5 2 3 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EER24107.1 - 6.8e-20 71.1 4.4 0.0029 17.9 0.0 7.3 7 1 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EER24107.1 - 2.2e-17 61.7 4.7 0.16 12.2 0.0 9.5 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER24107.1 - 9.8e-14 49.9 2.3 0.0051 16.5 0.0 7.2 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EER24107.1 - 2.2e-08 34.0 6.6 0.26 11.8 0.1 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EER24107.1 - 0.00081 18.5 0.7 0.14 11.2 0.1 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EER24107.1 - 0.0014 18.4 0.3 0.023 14.6 0.2 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 EER24107.1 - 0.01 15.8 0.5 3 7.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 EER24107.1 - 0.012 15.4 0.2 46 3.9 0.0 4.8 3 2 2 5 5 5 0 Tetratricopeptide repeat FAT PF02259.18 EER24107.1 - 0.018 14.0 1.9 0.1 11.5 0.3 2.8 3 1 0 3 3 3 0 FAT domain ChAPs PF09295.5 EER24107.1 - 0.023 13.4 0.0 2.2 6.9 0.0 2.2 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) PAZ_siRNAbind PF12212.3 EER24107.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Piwi/Argonaute/Zwille siRNA-binding domain APP_E2 PF12925.2 EER24107.1 - 0.22 11.0 1.3 1.9 8.0 0.2 2.5 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein TPR_4 PF07721.9 EER24107.1 - 0.24 11.9 1.4 1.9e+02 2.9 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat F-box PF00646.28 EER24108.1 - 1.9e-08 33.7 0.5 7.1e-08 31.9 0.3 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER24108.1 - 3.1e-07 30.0 2.1 6.2e-07 29.0 0.1 2.6 2 0 0 2 2 2 1 F-box-like PRANC PF09372.5 EER24108.1 - 0.00083 19.2 0.0 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 PRANC domain AAA-ATPase_like PF09820.4 EER24109.1 - 0.33 10.0 1.1 0.64 9.1 0.1 1.9 3 0 0 3 3 3 0 Predicted AAA-ATPase RINGv PF12906.2 EER24110.1 - 4.3e-16 58.6 9.0 7.3e-16 57.9 6.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EER24110.1 - 0.019 14.8 7.1 0.034 13.9 4.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EER24110.1 - 1.4 8.5 6.7 2.4 7.8 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EER24110.1 - 3.5 7.6 5.9 7.7 6.5 4.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain HeLo PF14479.1 EER24111.1 - 0.033 13.9 0.7 0.48 10.1 0.5 2.2 1 1 0 1 1 1 0 Prion-inhibition and propagation Pkinase PF00069.20 EER24111.1 - 0.068 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain ACC_central PF08326.7 EER24112.1 - 1.2e-262 873.1 0.0 1.7e-262 872.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EER24112.1 - 9.7e-181 601.4 0.0 1.8e-180 600.5 0.0 1.4 2 0 0 2 2 2 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EER24112.1 - 5.1e-52 176.2 0.0 9.6e-52 175.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EER24112.1 - 7.7e-24 83.9 0.0 1.4e-23 83.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EER24112.1 - 2.5e-22 78.8 0.0 5.9e-20 71.2 0.0 3.3 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EER24112.1 - 9.3e-14 50.8 0.1 2.6e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EER24112.1 - 5.5e-09 36.0 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EER24112.1 - 6.2e-08 31.7 0.0 0.00093 18.0 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EER24112.1 - 0.00043 19.7 0.0 0.00097 18.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EER24112.1 - 0.002 18.0 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EER24112.1 - 0.051 12.9 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain NUDE_C PF04880.8 EER24113.1 - 7.6e-24 84.9 6.3 7.6e-24 84.9 4.4 3.7 3 1 0 3 3 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EER24113.1 - 1.7e-05 25.0 7.4 1.7e-05 25.0 5.1 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF904) ERM PF00769.14 EER24113.1 - 0.0012 18.4 3.3 0.0012 18.4 2.3 2.3 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Myosin_tail_1 PF01576.14 EER24113.1 - 0.017 12.8 25.7 0.026 12.2 17.8 1.1 1 0 0 1 1 1 0 Myosin tail ATG16 PF08614.6 EER24113.1 - 0.052 13.3 26.1 1.4 8.7 12.5 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EER24113.1 - 0.13 11.8 32.8 0.019 14.5 11.4 2.3 1 1 1 2 2 2 0 IncA protein DivIC PF04977.10 EER24113.1 - 0.8 9.2 27.5 0.26 10.8 1.9 4.1 3 1 1 4 4 4 0 Septum formation initiator AAA_13 PF13166.1 EER24113.1 - 0.85 7.9 17.5 1.3 7.4 12.1 1.1 1 0 0 1 1 1 0 AAA domain ADIP PF11559.3 EER24113.1 - 1.7 8.5 29.8 0.72 9.7 2.4 3.6 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding EAP30 PF04157.11 EER24113.1 - 1.8 7.6 9.4 0.11 11.5 0.3 2.6 2 1 1 3 3 3 0 EAP30/Vps36 family CENP-F_leu_zip PF10473.4 EER24113.1 - 4 7.2 31.5 63 3.4 5.9 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EER24113.1 - 6.5 5.8 28.9 1.4 8.0 2.8 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Isochorismatase PF00857.15 EER24114.1 - 5.8e-39 133.7 0.0 9.2e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Sedlin_N PF04628.8 EER24115.1 - 3.4e-41 140.2 0.0 3.9e-41 140.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EER24115.1 - 2.9e-05 23.7 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 2 Sybindin-like family DUF2040 PF09745.4 EER24116.1 - 6.3e-40 135.9 11.4 6.3e-40 135.9 7.9 4.3 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) AAA_23 PF13476.1 EER24116.1 - 0.68 10.2 24.0 0.12 12.7 5.9 2.3 2 0 0 2 2 2 0 AAA domain Zip PF02535.17 EER24117.1 - 5.2e-23 81.5 6.9 5.6e-22 78.1 4.8 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.18 EER24118.1 - 9.5e-61 205.0 0.0 1.2e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-C3HC4_2 PF13923.1 EER24119.1 - 1.7e-08 34.3 13.8 1.9e-05 24.6 1.8 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER24119.1 - 6.2e-05 22.7 11.5 0.0015 18.2 3.4 2.6 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EER24119.1 - 7.6e-05 22.3 13.1 0.00018 21.1 4.4 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EER24119.1 - 0.00024 20.7 2.7 0.00024 20.7 1.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EER24119.1 - 0.00051 19.6 2.3 0.00051 19.6 1.6 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EER24119.1 - 0.001 18.9 12.9 0.029 14.2 3.4 3.6 2 2 1 3 3 3 3 FYVE zinc finger Atg14 PF10186.4 EER24119.1 - 0.95 8.3 8.1 1.8 7.4 5.6 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RIG-I_C-RD PF11648.3 EER24119.1 - 1.1 9.1 7.9 0.26 11.1 2.1 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I IBR PF01485.16 EER24119.1 - 2 8.3 11.5 12 5.8 0.2 3.3 2 1 0 2 2 2 0 IBR domain CDC45 PF02724.9 EER24119.1 - 4.1 5.3 9.5 5.9 4.8 6.6 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-C3HC4_4 PF15227.1 EER24119.1 - 4.9 7.0 12.9 0.22 11.3 1.5 3.2 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING FRG2 PF15315.1 EER24119.1 - 6.6 6.6 14.5 0.71 9.8 6.9 1.6 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 SET PF00856.23 EER24120.1 - 3.4e-08 33.9 0.5 4.4e-07 30.3 0.0 2.9 3 1 0 3 3 3 1 SET domain PGC7_Stella PF15549.1 EER24120.1 - 0.029 14.3 0.1 0.071 13.0 0.1 1.7 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Vma12 PF11712.3 EER24120.1 - 0.11 12.2 0.2 0.21 11.3 0.2 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Sec7 PF01369.15 EER24121.1 - 8.3e-39 133.2 0.0 1.4e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EER24121.1 - 2.4e-07 30.9 0.1 5.1e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EER24121.1 - 4.4e-05 23.6 0.0 0.00012 22.2 0.0 1.8 1 0 0 1 1 1 1 PH domain Peptidase_M14 PF00246.19 EER24122.1 - 7.7e-68 229.1 0.0 1e-67 228.6 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase NicO PF03824.11 EER24123.1 - 1.4e-45 155.8 10.2 3.3e-41 141.4 2.9 2.0 2 0 0 2 2 2 2 High-affinity nickel-transport protein Dynamin_N PF00350.18 EER24124.1 - 5.4e-06 26.3 0.0 1.7e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Dynamin family DNA_pol_lambd_f PF10391.4 EER24125.1 - 1.4e-20 72.5 0.2 3e-20 71.4 0.2 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EER24125.1 - 1.2e-18 66.5 0.0 4.6e-18 64.6 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EER24125.1 - 1.9e-14 53.6 0.5 1e-13 51.3 0.3 2.1 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EER24125.1 - 1.7e-08 34.4 0.0 4.6e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HAD PF12710.2 EER24126.1 - 1.3e-19 71.1 0.1 3.6e-19 69.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EER24126.1 - 4.6e-17 61.8 0.0 8.3e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EER24126.1 - 4.7e-13 50.0 0.0 2.3e-12 47.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER24126.1 - 2.8e-12 46.4 0.0 6.7e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EER24126.1 - 0.0017 18.0 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EER24126.1 - 0.016 15.4 0.2 0.051 13.8 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 EER24127.1 - 3.1e-20 72.8 0.0 6.4e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EER24127.1 - 0.0018 18.2 0.1 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 EER24128.1 - 4.6e-75 252.4 14.7 5.4e-75 252.2 10.2 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 EER24128.1 - 0.001 18.6 3.7 0.0013 18.2 2.6 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF2890 PF11081.3 EER24128.1 - 0.001 19.1 12.8 0.0018 18.3 8.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) DUF3752 PF12572.3 EER24128.1 - 0.11 12.6 11.5 0.15 12.1 8.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) APG6 PF04111.7 EER24128.1 - 1.2 8.0 10.9 1.8 7.5 7.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 YqfQ PF14181.1 EER24128.1 - 2.8 7.9 8.8 5.5 6.9 6.1 1.4 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 EER24128.1 - 6.1 6.1 8.1 8.4 5.7 5.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 DHFR_1 PF00186.14 EER24130.1 - 1.5e-16 60.3 0.3 5.3e-09 35.8 0.0 4.1 3 2 0 3 3 3 3 Dihydrofolate reductase Voltage_CLC PF00654.15 EER24131.1 - 9.2e-92 307.7 26.8 1.6e-91 306.9 16.7 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel Lipase_GDSL_2 PF13472.1 EER24132.1 - 4.4e-25 88.8 0.0 5.3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EER24132.1 - 1.4e-23 83.9 0.0 1.6e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EER24132.1 - 0.0005 19.8 0.0 0.013 15.2 0.0 2.3 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Isochorismatase PF00857.15 EER24134.1 - 3.7e-26 92.1 0.0 4.7e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.10 EER24135.1 - 1.5e-72 243.7 1.3 2.6e-72 242.9 0.1 1.8 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EER24135.1 - 9.3e-58 194.3 1.9 1.4e-57 193.7 1.3 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI eIF-5_eIF-2B PF01873.12 EER24136.1 - 2.7e-38 130.4 0.0 4.6e-38 129.6 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EER24136.1 - 5.7e-25 87.0 0.2 1.5e-24 85.6 0.1 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Daxx PF03344.10 EER24136.1 - 0.89 7.9 13.4 1.2 7.5 9.3 1.1 1 0 0 1 1 1 0 Daxx Family CFEM PF05730.6 EER24138.1 - 1.8e-13 50.0 4.7 3e-13 49.3 3.2 1.3 1 0 0 1 1 1 1 CFEM domain DNA_ligase_A_M PF01068.16 EER24140.1 - 1.7e-56 190.8 0.2 2.9e-44 150.8 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EER24140.1 - 6.5e-56 188.9 0.0 1.2e-55 188.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EER24140.1 - 7.4e-28 96.8 0.0 3.4e-27 94.6 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 EER24141.1 - 2.1e-50 171.1 0.5 3.1e-50 170.5 0.4 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EER24141.1 - 1.1e-23 83.5 0.0 2.3e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EER24141.1 - 1.1e-08 34.7 0.4 6.3e-07 28.9 0.3 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain SCA7 PF08313.7 EER24142.1 - 5.9e-34 115.5 0.7 5.9e-34 115.5 0.5 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf-H2C2 PF09337.5 EER24142.1 - 0.12 11.8 0.4 2.4 7.6 0.0 2.5 2 1 0 2 2 2 0 His(2)-Cys(2) zinc finger CDC45 PF02724.9 EER24142.1 - 0.14 10.1 7.8 0.18 9.8 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3505 PF12013.3 EER24142.1 - 0.2 11.9 3.8 0.5 10.6 2.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3505) Borrelia_P83 PF05262.6 EER24142.1 - 5.5 5.1 15.7 7 4.8 10.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2201_N PF13203.1 EER24142.1 - 5.9 5.9 10.4 13 4.8 7.2 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain U79_P34 PF03064.11 EER24142.1 - 7.6 5.9 19.1 13 5.2 13.2 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AIRC PF00731.15 EER24143.1 - 9.6e-60 200.2 1.1 1.7e-59 199.3 0.8 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EER24143.1 - 3e-54 182.9 0.2 8.4e-54 181.4 0.0 1.8 3 0 0 3 3 3 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EER24143.1 - 1.8e-11 44.1 0.0 8.8e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EER24143.1 - 1.5e-06 27.6 0.2 4.1e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EER24143.1 - 3.2e-05 23.4 0.0 0.00067 19.0 0.0 2.3 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EER24143.1 - 0.00067 18.5 0.0 0.028 13.1 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon PrpR_N PF06506.6 EER24143.1 - 0.0026 17.2 0.7 0.028 13.8 0.1 2.7 3 0 0 3 3 3 1 Propionate catabolism activator 2-Hacid_dh_C PF02826.14 EER24143.1 - 0.0042 16.2 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EER24143.1 - 0.12 12.5 1.5 14 5.9 0.1 3.0 2 1 1 3 3 3 0 CoA binding domain ketoacyl-synt PF00109.21 EER24144.1 - 4.8e-46 157.3 3.2 3.3e-45 154.5 0.7 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EER24144.1 - 1.4e-33 115.2 0.4 1.4e-32 112.0 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EER24144.1 - 2e-05 23.7 0.2 4.9e-05 22.4 0.1 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EER24144.1 - 0.0036 16.7 1.0 0.35 10.2 0.1 3.2 3 0 0 3 3 3 1 Thiolase, C-terminal domain Arginase PF00491.16 EER24145.1 - 2.7e-91 305.7 0.0 3.1e-91 305.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EER24145.1 - 0.024 14.8 0.1 0.038 14.1 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Ras PF00071.17 EER24146.1 - 1.7e-52 177.1 0.0 2e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER24146.1 - 1.6e-16 60.8 0.0 2.4e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER24146.1 - 4.9e-06 25.8 0.0 6.9e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family p450 PF00067.17 EER24148.1 - 8.9e-33 113.4 0.0 1.1e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EER24149.1 - 5.8e-24 84.4 40.3 2.6e-22 79.0 28.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.7 EER24149.1 - 0.0065 16.4 0.1 0.0065 16.4 0.1 2.4 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 DUF1349 PF07081.6 EER24150.1 - 1.8e-28 99.1 0.0 2.1e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) ABC_membrane PF00664.18 EER24151.1 - 2.5e-94 315.7 24.2 1.4e-50 172.2 3.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EER24151.1 - 1.9e-67 225.7 0.1 2.8e-33 115.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EER24151.1 - 1.5e-11 44.8 0.6 0.025 14.5 0.0 4.3 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EER24151.1 - 1.6e-11 43.8 3.5 0.00059 19.1 0.1 3.9 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EER24151.1 - 2.3e-08 34.2 1.7 0.00098 19.1 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EER24151.1 - 2.9e-08 32.7 0.8 0.00073 18.2 0.1 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EER24151.1 - 3.5e-08 32.8 0.3 0.00047 19.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EER24151.1 - 6.4e-08 33.4 0.1 0.0045 17.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EER24151.1 - 2.9e-07 29.8 0.1 0.024 13.8 0.0 3.0 2 1 1 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EER24151.1 - 6.7e-06 26.2 0.6 0.12 12.5 0.0 3.5 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EER24151.1 - 3.6e-05 23.4 0.2 0.53 9.8 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EER24151.1 - 4.3e-05 23.2 0.2 0.071 12.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EER24151.1 - 0.0001 22.5 0.1 0.31 11.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EER24151.1 - 0.00027 20.7 5.7 0.2 11.5 0.4 4.1 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EER24151.1 - 0.00028 20.0 0.2 0.092 11.8 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin AAA_14 PF13173.1 EER24151.1 - 0.00044 20.1 0.0 3.3 7.6 0.0 4.0 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.15 EER24151.1 - 0.00059 18.6 0.0 0.035 12.7 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_25 PF13481.1 EER24151.1 - 0.0013 18.2 0.3 3.6 6.9 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 EER24151.1 - 0.0025 17.8 0.4 0.82 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EER24151.1 - 0.0031 17.7 0.9 3 8.0 0.2 3.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EER24151.1 - 0.0069 15.8 0.2 4.3 6.7 0.0 2.7 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EER24151.1 - 0.01 15.6 0.0 4.4 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EER24151.1 - 0.015 15.6 0.2 5.6 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EER24151.1 - 0.02 14.3 0.1 0.1 12.1 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.1 EER24151.1 - 0.036 13.1 0.0 0.56 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EER24151.1 - 0.039 13.3 1.6 8.7 5.6 0.0 3.5 4 0 0 4 4 4 0 AAA-like domain DUF87 PF01935.12 EER24151.1 - 0.044 13.6 0.5 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 APS_kinase PF01583.15 EER24151.1 - 0.044 13.4 0.2 2.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 EER24151.1 - 0.072 12.5 0.0 0.84 9.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family PRK PF00485.13 EER24151.1 - 0.075 12.5 0.3 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EER24151.1 - 0.11 11.3 0.4 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain CAP59_mtransfer PF11735.3 EER24152.1 - 3.5e-74 249.0 0.0 5e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 AstA PF04958.7 EER24153.1 - 0.036 12.4 0.0 0.058 11.8 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit DUF3763 PF12592.3 EER24154.1 - 0.077 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) GST_C PF00043.20 EER24155.1 - 5.1e-14 52.0 0.3 7.9e-14 51.4 0.2 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EER24155.1 - 2.9e-12 46.5 0.0 2e-11 43.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EER24155.1 - 2.1e-11 43.8 0.0 4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EER24155.1 - 1.3e-10 41.1 0.0 2.8e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EER24155.1 - 2.1e-07 31.3 0.4 3.1e-07 30.7 0.3 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EER24155.1 - 4.4e-05 23.2 0.2 0.00013 21.7 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1762 PF08574.5 EER24156.1 - 8.4e-17 61.3 14.4 3.5e-16 59.3 10.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1762) RRM_1 PF00076.17 EER24157.1 - 3.2e-38 129.1 0.0 1.9e-11 43.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER24157.1 - 2.7e-36 123.3 0.0 8.6e-09 35.2 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER24157.1 - 1.4e-18 66.4 0.0 4.3e-05 23.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EER24157.1 - 1.1e-08 34.5 4.3 1.1e-08 34.5 3.0 3.0 2 0 0 2 2 2 1 Putative RRM domain RRM_3 PF08777.6 EER24157.1 - 0.00012 21.9 0.4 0.34 10.7 0.0 2.8 3 0 0 3 3 3 2 RNA binding motif RNA_bind PF08675.6 EER24157.1 - 0.086 12.8 0.0 0.66 10.0 0.0 2.5 2 0 0 2 2 2 0 RNA binding domain YL1 PF05764.8 EER24158.1 - 5.8e-62 209.4 30.7 5.8e-62 209.4 21.2 2.0 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 EER24158.1 - 4e-13 48.6 0.2 6.7e-13 47.9 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain tRNA-synt_2 PF00152.15 EER24159.1 - 2.8e-72 243.3 0.0 4.6e-72 242.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EER24159.1 - 3.7e-08 33.0 0.0 6.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PUF PF00806.14 EER24160.1 - 2.7e-27 92.6 0.0 1.7e-05 24.0 0.0 6.0 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EER24160.1 - 1.1e-10 40.9 0.0 2.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER24160.1 - 2.4e-08 33.7 0.0 6.6e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER24160.1 - 4.4e-05 23.3 0.0 0.00012 21.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AMPKBI PF04739.10 EER24160.1 - 2.1 8.2 7.9 0.27 11.0 0.1 3.1 4 0 0 4 4 4 0 5'-AMP-activated protein kinase beta subunit, interation domain BAF1_ABF1 PF04684.8 EER24160.1 - 2.3 6.9 5.8 3.7 6.2 4.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MT-A70 PF05063.9 EER24161.1 - 7.4e-22 77.7 0.0 1.1e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EER24161.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_C12 PF01088.16 EER24162.1 - 1.2e-63 214.1 0.0 1.4e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DcpS_C PF11969.3 EER24163.1 - 9.4e-29 99.9 0.1 1.4e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EER24163.1 - 1.1e-28 99.8 0.0 1.8e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Alk_phosphatase PF00245.15 EER24164.1 - 2.5e-71 240.6 0.2 3.3e-71 240.2 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EER24164.1 - 3.9e-07 29.5 4.0 3.1e-06 26.6 2.7 2.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EER24164.1 - 9.3e-05 21.9 3.0 0.00014 21.3 2.0 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EER24164.1 - 0.0019 16.7 0.2 0.0028 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) FTA4 PF13093.1 EER24164.1 - 0.059 12.7 0.1 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Metalloenzyme PF01676.13 EER24164.1 - 0.06 12.7 0.6 0.17 11.2 0.4 1.7 1 0 0 1 1 1 0 Metalloenzyme superfamily HHH_3 PF12836.2 EER24164.1 - 0.14 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif RNase_H2_suC PF08615.6 EER24165.1 - 9e-30 103.3 0.0 1.1e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CENP-B_dimeris PF09026.5 EER24165.1 - 0.26 11.5 2.8 0.4 10.9 2.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RNase_T PF00929.19 EER24166.1 - 9.9e-30 103.9 0.0 1.5e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Nop53 PF07767.6 EER24167.1 - 8.3e-115 383.8 31.8 1e-114 383.5 22.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Asp-B-Hydro_N PF05279.6 EER24167.1 - 0.12 12.2 22.4 0.23 11.2 15.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Myb_Cef PF11831.3 EER24168.1 - 5.4e-59 199.2 5.3 5.4e-59 199.2 3.7 3.4 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EER24168.1 - 3.3e-20 71.8 3.9 2.1e-09 37.2 0.3 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER24168.1 - 2.5e-19 69.1 5.6 1.1e-12 47.9 1.0 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain MOZ_SAS PF01853.13 EER24169.1 - 5.6e-85 283.3 0.0 7.9e-85 282.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EER24169.1 - 6.2e-22 77.0 0.0 1.3e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EER24169.1 - 0.12 12.3 0.1 0.34 10.9 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family F1F0-ATPsyn_F PF10791.4 EER24171.1 - 5.3e-35 119.5 0.5 6.7e-35 119.2 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EER24171.1 - 6.3e-05 22.9 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EER24172.1 - 4.2e-36 122.8 1.1 7e-36 122.1 0.7 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region HEAT_2 PF13646.1 EER24173.1 - 1.7e-33 114.7 6.0 1.5e-14 54.0 0.0 4.1 2 2 3 5 5 5 4 HEAT repeats HEAT_PBS PF03130.11 EER24173.1 - 1.8e-19 68.1 0.9 0.018 15.4 0.4 7.3 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT PF02985.17 EER24173.1 - 2.4e-07 30.2 4.5 1.5 9.1 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EER24173.1 - 6.8e-07 29.5 7.8 0.0026 18.1 0.0 5.1 4 2 1 5 5 5 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EER24173.1 - 0.014 15.3 0.7 0.092 12.7 0.0 2.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Arm PF00514.18 EER24173.1 - 0.026 14.3 0.1 14 5.6 0.0 3.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat TFIIS_C PF01096.13 EER24174.1 - 8.3e-15 54.1 1.8 8.3e-15 54.1 1.3 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EER24174.1 - 6e-07 29.0 8.3 2.8e-06 26.9 0.8 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 EER24174.1 - 0.013 15.3 6.6 0.67 9.8 2.7 2.6 1 1 1 2 2 2 0 Double zinc ribbon RecR PF02132.10 EER24174.1 - 0.013 14.9 1.1 0.013 14.9 0.8 2.4 2 0 0 2 2 2 0 RecR protein XPA_N PF01286.13 EER24174.1 - 0.077 12.6 3.2 8 6.2 0.0 3.3 3 0 0 3 3 3 0 XPA protein N-terminal Ribosomal_S27e PF01667.12 EER24174.1 - 0.15 11.5 3.4 1.7 8.2 0.0 3.1 2 1 1 3 3 3 0 Ribosomal protein S27 Lar_restr_allev PF14354.1 EER24174.1 - 0.16 12.2 7.6 1.1 9.5 0.8 3.1 1 1 1 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.1 EER24174.1 - 0.26 10.8 9.1 12 5.4 0.0 3.9 3 1 1 4 4 4 0 zinc-ribbon domain RNHCP PF12647.2 EER24174.1 - 0.3 10.9 3.9 1.4 8.7 1.7 2.5 1 1 0 1 1 1 0 RNHCP domain Auto_anti-p27 PF06677.7 EER24174.1 - 0.49 10.2 3.1 7.4 6.4 0.0 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) PHD PF00628.24 EER24174.1 - 0.54 9.9 5.2 7.3 6.3 1.6 2.9 2 1 1 3 3 3 0 PHD-finger zf-dskA_traR PF01258.12 EER24174.1 - 0.9 9.3 4.3 25 4.7 0.1 3.2 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger ADK_lid PF05191.9 EER24174.1 - 0.94 9.2 6.4 9.4 5.9 1.5 2.7 2 1 0 2 2 2 0 Adenylate kinase, active site lid C1_1 PF00130.17 EER24174.1 - 1.1 9.0 5.1 0.96 9.2 0.1 2.3 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.1 EER24174.1 - 1.2 9.5 4.9 40 4.7 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Zn_ribbon_recom PF13408.1 EER24174.1 - 1.2 9.4 5.8 34 4.8 1.1 3.2 2 2 1 3 3 3 0 Recombinase zinc beta ribbon domain Nudix_N_2 PF14803.1 EER24174.1 - 1.5 8.5 11.0 0.17 11.6 0.5 2.7 3 1 0 3 3 2 0 Nudix N-terminal OrfB_Zn_ribbon PF07282.6 EER24174.1 - 2.2 7.9 6.7 0.94 9.1 0.1 2.5 2 1 1 3 3 3 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EER24174.1 - 5.4 6.3 10.9 6.8 6.0 1.6 3.4 3 1 0 3 3 3 0 zinc-ribbon domain zf-CSL PF05207.8 EER24174.1 - 7.1 6.2 11.7 0.6 9.6 0.5 3.1 2 1 1 3 3 3 0 CSL zinc finger Nipped-B_C PF12830.2 EER24175.1 - 2.8e-56 190.1 5.9 1.7e-53 181.0 0.9 3.7 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EER24175.1 - 6e-13 48.4 4.4 1.9e-12 46.8 1.3 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EER24175.1 - 3.7e-05 23.4 2.8 0.14 12.3 0.1 5.0 4 0 0 4 4 4 1 HEAT repeat Pyr_redox_2 PF07992.9 EER24176.1 - 7.9e-18 65.0 0.0 1.2e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER24176.1 - 4.7e-11 42.9 0.0 1.7e-09 37.9 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EER24176.1 - 7.2e-07 28.0 0.1 3e-06 26.1 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EER24176.1 - 3.9e-06 26.2 0.5 1.4e-05 24.5 0.3 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EER24176.1 - 2.5e-05 23.4 0.4 7.2e-05 21.9 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EER24176.1 - 5.9e-05 23.1 0.1 0.00015 21.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EER24176.1 - 0.082 12.5 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair CLTH PF10607.4 EER24177.1 - 2.2e-34 118.2 0.9 3.5e-34 117.5 0.6 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EER24177.1 - 7.7e-09 35.0 0.0 1.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 LisH PRK PF00485.13 EER24178.1 - 1.7e-55 187.5 0.0 2e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EER24178.1 - 4.3e-08 33.9 0.1 9.6e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EER24178.1 - 1.5e-07 31.8 0.0 2.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.12 EER24178.1 - 0.0002 21.2 0.3 0.00025 20.9 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EER24178.1 - 0.00024 20.2 0.0 0.00038 19.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.7 EER24178.1 - 0.0019 17.8 0.2 0.0061 16.1 0.0 1.9 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 EER24178.1 - 0.0075 15.7 0.2 0.011 15.2 0.1 1.6 1 1 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EER24178.1 - 0.013 14.9 0.0 0.037 13.5 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EER24178.1 - 0.021 14.6 0.0 0.046 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EER24178.1 - 0.025 14.8 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EER24178.1 - 0.032 14.2 0.1 0.085 12.8 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 EER24178.1 - 0.044 13.4 0.1 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase NB-ARC PF00931.17 EER24178.1 - 0.047 12.5 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CoaE PF01121.15 EER24178.1 - 0.047 13.0 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase Cytidylate_kin2 PF13189.1 EER24178.1 - 0.067 13.0 0.1 4.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase-like family CbiA PF01656.18 EER24178.1 - 0.077 12.3 0.2 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP-synt_ab PF00006.20 EER24178.1 - 0.085 12.3 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EER24178.1 - 0.094 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EER24178.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 EER24178.1 - 0.12 11.3 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain UPF0079 PF02367.12 EER24178.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NUC153 PF08159.7 EER24179.1 - 8.1e-14 50.9 11.5 2.2e-11 43.1 0.1 3.9 3 0 0 3 3 3 3 NUC153 domain Npa1 PF11707.3 EER24180.1 - 7.3e-97 324.3 0.0 1.4e-96 323.4 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal HEAT_EZ PF13513.1 EER24180.1 - 0.002 18.5 0.2 1 9.9 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat HA2 PF04408.18 EER24182.1 - 4e-29 100.6 0.1 1.1e-28 99.2 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EER24182.1 - 3.4e-26 91.2 0.0 1.3e-25 89.4 0.1 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EER24182.1 - 2.5e-12 46.4 0.6 8.5e-12 44.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.18 EER24182.1 - 2.3e-09 37.2 0.3 4.5e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EER24182.1 - 1.1e-05 25.0 0.1 2.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EER24182.1 - 0.00041 19.3 0.0 0.00098 18.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EER24182.1 - 0.001 19.2 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER24182.1 - 0.0017 18.0 0.3 0.0056 16.4 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain DUF1509 PF07420.6 EER24182.1 - 0.0074 15.6 9.3 0.016 14.5 6.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) SUV3_C PF12513.3 EER24183.1 - 3.3e-16 58.4 0.2 1.2e-15 56.6 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EER24183.1 - 1.1e-09 38.0 0.0 2.6e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sec1 PF00995.18 EER24184.1 - 2.7e-133 445.5 0.0 3.3e-133 445.3 0.0 1.1 1 0 0 1 1 1 1 Sec1 family G-patch PF01585.18 EER24185.1 - 2.6e-07 30.3 0.1 6.5e-07 29.0 0.0 1.7 1 1 1 2 2 2 2 G-patch domain DUF1178 PF06676.6 EER24185.1 - 0.045 13.9 1.2 0.26 11.4 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) adh_short PF00106.20 EER24186.1 - 3.1e-12 46.7 0.1 3.1e-11 43.4 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EER24186.1 - 8.2e-08 32.1 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EER24186.1 - 0.016 14.6 0.2 0.067 12.6 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EER24186.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF3792 PF12670.2 EER24186.1 - 0.43 10.4 4.4 0.087 12.6 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) Epimerase PF01370.16 EER24187.1 - 2.1e-44 151.7 0.0 3.4e-44 151.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EER24187.1 - 1.7e-26 91.8 0.1 3.1e-26 91.0 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EER24187.1 - 1.1e-15 57.0 0.0 1.7e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EER24187.1 - 1.4e-10 40.5 0.0 2.1e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EER24187.1 - 1.4e-10 40.5 0.0 1.3e-08 34.0 0.0 2.1 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein adh_short PF00106.20 EER24187.1 - 4.2e-10 39.7 0.0 6.8e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EER24187.1 - 7.1e-07 28.3 0.0 2.3e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EER24187.1 - 1.4e-06 28.1 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EER24187.1 - 5.3e-05 23.3 0.0 9.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Phage_lysozyme PF00959.14 EER24187.1 - 0.017 15.3 0.2 0.92 9.8 0.1 2.3 2 0 0 2 2 2 0 Phage lysozyme NAD_binding_10 PF13460.1 EER24188.1 - 8.5e-25 87.8 0.0 1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EER24188.1 - 1.8e-09 37.2 0.0 2.5e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EER24188.1 - 2.6e-08 33.6 0.0 7.4e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EER24188.1 - 7.1e-05 21.9 0.0 0.0001 21.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EER24188.1 - 0.0024 17.8 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EER24188.1 - 0.013 14.2 0.0 0.019 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Med28 PF11594.3 EER24188.1 - 0.072 13.3 0.1 9.5 6.5 0.0 2.7 3 0 0 3 3 3 0 Mediator complex subunit 28 NAD_binding_7 PF13241.1 EER24188.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding DFP PF04127.10 EER24188.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein PAT1 PF09770.4 EER24189.1 - 1.5e-266 886.7 15.4 1.8e-266 886.4 10.7 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 EER24190.1 - 8.8e-141 468.6 6.9 1e-140 468.3 4.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ribosom_S12_S23 PF00164.20 EER24191.1 - 5.7e-43 145.2 1.8 7.4e-43 144.8 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UMP1 PF05348.6 EER24192.1 - 4.3e-22 78.4 0.1 5.3e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Rad60-SLD_2 PF13881.1 EER24193.1 - 4.6e-10 39.3 0.0 9.3e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EER24193.1 - 0.0035 16.6 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EER24193.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain GHMP_kinases_N PF00288.21 EER24194.1 - 4.1e-14 52.3 0.4 1.1e-13 51.0 0.3 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EER24194.1 - 4.2e-07 30.0 0.0 8.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal THOC7 PF05615.8 EER24194.1 - 0.076 13.2 0.9 0.13 12.5 0.6 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Viral_P18 PF04521.8 EER24194.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein MCM PF00493.18 EER24195.1 - 4.8e-133 443.0 0.4 8.1e-133 442.3 0.0 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EER24195.1 - 2e-19 70.2 0.1 2e-19 70.2 0.0 2.4 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EER24195.1 - 4.1e-05 22.8 0.0 0.00017 20.8 0.0 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EER24195.1 - 0.00026 20.7 0.1 0.0064 16.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EER24195.1 - 0.0085 15.5 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EER24195.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Helicase_C PF00271.26 EER24196.1 - 7.8e-06 25.6 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EER24196.1 - 0.0062 16.1 10.3 0.019 14.6 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1186 PF06685.6 EER24196.1 - 0.0082 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1186) zf-RING_5 PF14634.1 EER24196.1 - 0.13 11.9 10.3 0.31 10.8 7.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EER24196.1 - 0.24 11.2 6.2 0.099 12.5 2.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EER24196.1 - 0.25 11.0 9.2 0.5 10.0 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER24196.1 - 0.92 9.5 10.7 2.4 8.2 7.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DLIC PF05783.6 EER24197.1 - 0.32 9.6 6.6 0.52 8.9 4.6 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) FNIP_N PF14636.1 EER24198.1 - 6.1e-26 91.4 0.1 6.1e-26 91.4 0.1 3.7 4 0 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EER24198.1 - 0.035 13.6 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Ribosomal_L7Ae PF01248.21 EER24199.1 - 1.7e-25 88.3 0.0 2.3e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EER24199.1 - 0.00029 20.6 0.0 0.00041 20.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 Fungal_trans PF04082.13 EER24200.1 - 6.6e-25 87.4 0.0 1.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER24200.1 - 4.8e-05 23.1 7.8 8.5e-05 22.3 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_Ca_ex PF01699.19 EER24202.1 - 1e-42 145.0 32.2 2.3e-23 82.3 7.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3608 PF12257.3 EER24203.1 - 6.5e-75 251.6 0.0 1.3e-74 250.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EER24203.1 - 2.9e-30 103.8 1.6 5.8e-30 102.8 1.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PPR_2 PF13041.1 EER24204.1 - 2.2e-41 139.5 16.5 6.5e-10 38.8 0.0 12.8 8 5 6 14 14 14 8 PPR repeat family PPR_3 PF13812.1 EER24204.1 - 9e-34 112.9 11.4 0.00029 20.8 0.0 13.9 13 0 0 13 13 13 8 Pentatricopeptide repeat domain PPR PF01535.15 EER24204.1 - 3.6e-25 86.1 21.0 0.00041 20.1 0.0 14.1 16 0 0 16 16 16 6 PPR repeat PPR_1 PF12854.2 EER24204.1 - 1.6e-20 72.2 6.6 1.5e-07 30.7 0.0 9.9 11 0 0 11 11 11 4 PPR repeat RPM2 PF08579.6 EER24204.1 - 0.00022 21.3 0.1 0.01 15.9 0.0 3.4 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.1 EER24204.1 - 0.00023 21.4 0.2 2.2 8.6 0.0 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat RPN7 PF10602.4 EER24204.1 - 0.00028 20.2 0.1 0.38 10.1 0.0 3.6 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EER24204.1 - 0.0013 19.2 8.4 33 5.4 0.1 7.8 8 1 1 9 9 9 0 Tetratricopeptide repeat ECSIT PF06239.6 EER24204.1 - 0.1 11.4 0.1 20 3.9 0.0 3.4 3 0 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway PNPOx_C PF10590.4 EER24205.1 - 3.8e-20 71.0 6.4 1.9e-19 68.8 3.2 2.5 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EER24205.1 - 8.6e-10 38.5 0.2 0.00095 19.1 0.0 3.2 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase EamA PF00892.15 EER24206.1 - 0.00056 19.9 9.4 0.00071 19.6 6.3 1.5 1 1 0 1 1 1 1 EamA-like transporter family UPF0546 PF10639.4 EER24206.1 - 0.0006 19.6 4.5 0.00082 19.1 3.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EmrE PF13536.1 EER24206.1 - 0.00085 19.5 5.7 0.0017 18.5 4.0 1.5 1 0 0 1 1 1 1 Multidrug resistance efflux transporter DUF543 PF04418.7 EER24206.1 - 0.011 15.6 0.4 0.026 14.4 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF543) Ca_hom_mod PF14798.1 EER24206.1 - 0.064 12.2 1.9 0.1 11.5 1.3 1.2 1 0 0 1 1 1 0 Calcium homeostasis modulator Voltage_CLC PF00654.15 EER24207.1 - 2.4e-88 296.5 31.0 2.4e-88 296.5 21.5 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EER24207.1 - 4.9e-13 48.6 0.0 4.5e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 EER24208.1 - 7e-15 54.8 0.3 7e-15 54.8 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EER24208.1 - 0.00093 19.2 0.4 0.0015 18.6 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 UCR_TM PF02921.9 EER24209.1 - 7e-18 64.6 2.7 1.3e-17 63.7 1.8 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EER24209.1 - 5.3e-17 61.1 0.0 8.3e-17 60.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain She9_MDM33 PF05546.6 EER24210.1 - 5.5e-93 310.2 8.9 7.9e-93 309.7 6.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EER24210.1 - 0.02 14.4 0.5 0.02 14.4 0.4 1.9 2 0 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein PAS_9 PF13426.1 EER24210.1 - 0.14 12.5 0.1 0.35 11.2 0.0 1.7 1 0 0 1 1 1 0 PAS domain Pmp3 PF01679.12 EER24211.1 - 9.5e-19 66.8 7.2 1.3e-18 66.4 5.0 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CAP_N PF01213.14 EER24211.1 - 2.6 7.2 5.8 3.2 6.9 4.0 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SH3_9 PF14604.1 EER24212.1 - 5.1e-08 32.3 0.3 1.1e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EER24212.1 - 0.00024 20.4 0.1 0.00051 19.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain Tr-sialidase_C PF11052.3 EER24212.1 - 0.069 13.0 1.5 0.14 12.0 0.2 2.2 2 0 0 2 2 2 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal MFS_1 PF07690.11 EER24213.1 - 8.3e-18 64.2 62.6 6.2e-17 61.3 40.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER24213.1 - 4.3e-07 28.5 27.5 7.2e-07 27.7 19.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EER24213.1 - 0.16 11.9 4.2 0.5 10.3 1.4 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 CFEM PF05730.6 EER24214.1 - 1.7e-10 40.5 4.7 2.6e-10 39.9 3.2 1.3 1 0 0 1 1 1 1 CFEM domain Period_C PF12114.3 EER24214.1 - 9.6 5.7 8.1 15 5.1 5.6 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF221 PF02714.10 EER24217.1 - 2.7e-113 378.0 20.2 1.3e-112 375.9 13.8 2.7 4 0 0 4 4 4 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EER24217.1 - 4.1e-44 149.9 0.7 4.1e-44 149.9 0.5 3.0 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EER24217.1 - 1.6e-32 111.2 0.1 3.6e-32 110.0 0.1 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EER24217.1 - 8.8e-18 64.6 0.0 1.6e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUP PF00674.13 EER24219.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 DUP family zf-AD PF07776.10 EER24219.1 - 0.64 10.0 4.0 31 4.6 2.2 2.8 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) XPA_N PF01286.13 EER24219.1 - 5.2 6.8 7.9 2.6 7.8 1.9 2.5 2 0 0 2 2 2 0 XPA protein N-terminal Pyridox_oxase_2 PF12766.2 EER24220.1 - 1.9e-23 82.6 0.0 5.7e-23 81.1 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF818 PF05677.7 EER24220.1 - 0.19 10.4 0.0 0.3 9.7 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) LRR_9 PF14580.1 EER24221.1 - 5.2e-54 182.4 1.3 8.2e-54 181.8 0.0 1.7 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EER24221.1 - 8.9e-11 41.1 8.5 7.7e-06 25.4 0.8 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER24221.1 - 2.9e-09 36.5 6.0 9.2e-09 34.9 0.8 2.8 3 0 0 3 3 3 1 Leucine rich repeat HTH_38 PF13936.1 EER24221.1 - 0.0013 18.2 1.0 0.0032 16.9 0.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_1 PF00560.28 EER24221.1 - 0.014 15.2 7.0 5.3 7.4 0.0 4.8 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 EER24221.1 - 0.086 12.9 3.0 3 8.2 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 EER24221.1 - 0.29 11.4 5.9 36 5.1 0.1 4.5 4 1 0 4 4 4 0 Leucine rich repeat GDA1_CD39 PF01150.12 EER24222.1 - 5.8e-106 354.5 0.0 7.9e-106 354.1 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Velvet PF11754.3 EER24223.1 - 7.3e-08 32.2 0.0 4.7e-07 29.6 0.0 1.9 1 1 0 2 2 2 1 Velvet factor Acyltransferase PF01553.16 EER24224.1 - 1.1e-17 63.7 0.0 2.3e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase HTH_Crp_2 PF13545.1 EER24224.1 - 0.007 16.1 0.2 1.7 8.5 0.0 3.3 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain KNOX1 PF03790.8 EER24224.1 - 0.059 12.7 0.5 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 KNOX1 domain Pantoate_ligase PF02569.10 EER24225.1 - 5.5e-84 281.2 0.0 3.1e-82 275.4 0.0 2.1 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 EER24226.1 - 9.6e-40 135.8 0.0 1.6e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EER24226.1 - 4e-19 67.8 0.0 7.8e-19 66.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EER24226.1 - 9.9e-19 66.9 0.0 2.8e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER24226.1 - 0.0077 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WD40 PF00400.27 EER24227.1 - 7.1e-19 66.9 6.9 0.00052 19.8 0.0 7.3 6 2 0 6 6 6 5 WD domain, G-beta repeat Zn_clus PF00172.13 EER24228.1 - 3.2e-05 23.7 11.1 3.2e-05 23.7 7.7 2.3 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EER24229.1 - 5.6e-43 147.0 45.7 9e-41 139.7 31.7 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER24229.1 - 3.2e-08 32.6 20.6 3.2e-08 32.6 14.3 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EER24229.1 - 1.1e-05 23.8 18.6 1.5e-05 23.4 12.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.23 EER24230.1 - 3.2e-13 49.5 0.0 4.2e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EER24230.1 - 0.02 14.3 0.1 0.12 11.7 0.0 2.1 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.9 EER24230.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF775 PF05603.7 EER24231.1 - 5e-61 205.7 0.0 5.6e-61 205.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EER24232.1 - 2e-09 37.1 0.0 3.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF867 PF05908.6 EER24232.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF867) FlgM PF04316.8 EER24232.1 - 0.098 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM RNA_pol_Rpb8 PF03870.10 EER24233.1 - 1e-35 122.9 0.0 1.2e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EER24234.1 - 1.2e-117 392.8 0.0 1.4e-117 392.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EER24235.1 - 6.5e-15 54.7 0.0 1.6e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain UPF0086 PF01868.11 EER24236.1 - 8.7e-29 99.0 0.0 1.3e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Pkinase_Tyr PF07714.12 EER24236.1 - 0.038 13.0 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase 2OG-FeII_Oxy PF03171.15 EER24237.1 - 5.2e-14 52.3 0.0 1.1e-13 51.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EER24237.1 - 1e-13 51.8 0.0 1.7e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Copper-bind PF00127.15 EER24239.1 - 0.0053 16.9 0.0 0.0091 16.2 0.0 1.3 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EER24239.1 - 0.048 13.5 0.0 0.1 12.4 0.0 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain FYVE_2 PF02318.11 EER24240.1 - 0.0054 16.6 32.3 0.15 11.9 4.8 3.9 3 1 1 4 4 4 3 FYVE-type zinc finger zf-ribbon_3 PF13248.1 EER24240.1 - 0.0094 15.1 1.8 0.0094 15.1 1.2 3.7 5 0 0 5 5 5 2 zinc-ribbon domain Phage_Mu_F PF04233.9 EER24240.1 - 0.039 14.4 1.1 0.066 13.7 0.3 1.7 2 0 0 2 2 2 0 Phage Mu protein F like protein DUF3725 PF12523.3 EER24240.1 - 0.3 11.2 2.5 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3725) Cofilin_ADF PF00241.15 EER24241.1 - 1.5e-08 34.5 0.0 1.6e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 EER24242.1 - 3.2e-36 123.8 0.0 5.3e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EER24243.1 - 2.3e-59 199.3 0.2 2.8e-59 199.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER24243.1 - 1.5e-18 67.4 0.0 2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER24243.1 - 2e-08 33.7 0.0 2.2e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EER24243.1 - 8.8e-08 31.8 0.1 1.1e-06 28.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EER24243.1 - 0.0039 16.4 0.1 0.0077 15.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EER24243.1 - 0.0058 16.5 0.0 0.01 15.8 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EER24243.1 - 0.027 13.6 0.2 0.039 13.0 0.2 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EER24243.1 - 0.033 13.3 0.2 0.065 12.4 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EER24243.1 - 0.039 13.3 0.6 0.61 9.4 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 EER24243.1 - 0.31 10.5 2.1 2.2 7.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein adh_short PF00106.20 EER24244.1 - 2.8e-34 118.4 0.0 5.3e-34 117.5 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER24244.1 - 7e-16 58.7 0.0 9.3e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER24244.1 - 5.6e-13 48.9 0.0 8.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EER24244.1 - 0.00051 19.7 0.2 0.0012 18.6 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EER24244.1 - 0.0071 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EER24244.1 - 0.033 13.0 0.0 0.083 11.7 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AAA_22 PF13401.1 EER24244.1 - 0.035 14.2 0.0 0.095 12.8 0.0 1.7 2 1 0 2 2 2 0 AAA domain Lin0512_fam PF09585.5 EER24244.1 - 0.066 12.7 0.1 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) GATA PF00320.22 EER24246.1 - 6.3e-30 102.2 18.4 7.9e-16 57.1 3.5 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EER24246.1 - 4.2e-06 25.9 2.2 0.0014 17.9 0.0 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.2 EER24246.1 - 0.19 11.5 13.2 3.7e+02 1.0 9.2 3.2 1 1 0 1 1 1 0 Double zinc ribbon Auto_anti-p27 PF06677.7 EER24246.1 - 0.44 10.3 5.0 6.5 6.6 0.2 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.5 EER24246.1 - 0.76 9.7 6.9 1.2 9.1 0.2 2.8 3 0 0 3 3 3 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EER24246.1 - 1.1 8.5 10.8 0.38 10.0 0.5 2.9 2 1 0 2 2 2 0 zinc-ribbon domain COPI_assoc PF08507.5 EER24247.1 - 9.8e-38 128.9 2.9 1.1e-37 128.8 2.0 1.0 1 0 0 1 1 1 1 COPI associated protein DUF3096 PF11295.3 EER24247.1 - 0.04 13.4 0.4 0.04 13.4 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3096) HAP PF03866.8 EER24247.1 - 4.5 7.0 6.1 1.7 8.3 1.4 1.9 1 1 1 2 2 2 0 Hydrophobic abundant protein (HAP) YtpI PF14007.1 EER24247.1 - 6.1 6.8 7.7 5.4 7.0 0.3 2.2 2 0 0 2 2 2 0 YtpI-like protein Sugar_tr PF00083.19 EER24249.1 - 3.3e-98 329.1 21.5 3.9e-98 328.9 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER24249.1 - 8.5e-12 44.4 39.2 1.1e-11 44.0 4.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.3 EER24249.1 - 2.3 7.6 3.9 4.7 6.6 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) zf-CCHC PF00098.18 EER24250.1 - 7.5e-13 47.7 16.2 2.1e-07 30.5 0.7 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.1 EER24250.1 - 0.012 15.2 7.4 0.43 10.3 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.1 EER24250.1 - 0.055 12.9 3.7 0.081 12.4 0.1 2.6 2 1 1 3 3 3 0 Zinc knuckle PHD PF00628.24 EER24250.1 - 0.07 12.8 7.9 1 9.0 1.1 2.4 1 1 1 2 2 2 0 PHD-finger zf-CCHC_3 PF13917.1 EER24250.1 - 0.072 12.8 0.8 0.072 12.8 0.5 3.2 1 1 2 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 EER24250.1 - 0.22 11.2 12.8 0.39 10.4 0.7 3.2 3 0 0 3 3 3 0 Zinc knuckle HRM PF02793.17 EER24250.1 - 2.8 8.0 9.5 40 4.3 6.6 2.7 1 1 0 1 1 1 0 Hormone receptor domain zinc_ribbon_4 PF13717.1 EER24250.1 - 3.2 7.5 8.7 40 4.0 6.0 2.4 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EER24250.1 - 3.5 7.2 8.6 40 3.8 5.9 2.4 1 1 0 1 1 1 0 zinc-ribbon domain FAD_binding_3 PF01494.14 EER24251.1 - 7.3e-13 48.3 0.0 2.9e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EER24251.1 - 0.0025 17.5 0.0 0.42 10.3 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EER24251.1 - 0.0043 17.0 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EER24251.1 - 0.014 14.3 0.1 0.036 13.0 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EER24251.1 - 0.023 13.7 0.0 0.051 12.6 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF2937 PF11157.3 EER24251.1 - 0.031 13.5 0.0 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Pyr_redox_3 PF13738.1 EER24251.1 - 0.087 12.8 0.0 0.39 10.7 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EER24251.1 - 0.14 10.9 0.0 0.49 9.1 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase ECH PF00378.15 EER24252.1 - 1.5e-40 138.8 0.0 1.8e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EER24252.1 - 0.03 14.1 0.0 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Acyl-CoA_dh_1 PF00441.19 EER24253.1 - 9.7e-30 103.6 0.1 1.3e-29 103.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EER24253.1 - 5.3e-20 70.6 0.5 8.7e-20 69.9 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EER24253.1 - 2.1e-18 66.9 0.2 2.3e-17 63.5 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EER24253.1 - 0.023 14.9 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain HpcH_HpaI PF03328.9 EER24254.1 - 5.1e-45 153.0 0.0 1.3e-44 151.6 0.0 1.6 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EER24254.1 - 3e-14 52.5 0.1 2.5e-11 43.0 0.1 2.1 1 1 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold DUF1771 PF08590.5 EER24255.1 - 4.4e-14 52.2 7.0 1e-13 51.0 4.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EER24255.1 - 1.1e-10 41.5 0.0 5e-10 39.4 0.0 2.2 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EER24255.1 - 1.5e-08 34.0 0.6 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 EER24255.1 - 0.056 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 HBS1 N-terminus CUE PF02845.11 EER24255.1 - 0.076 12.5 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 CUE domain SNARE_assoc PF09335.6 EER24256.1 - 7.6e-12 45.5 5.6 7.6e-12 45.5 3.9 2.7 2 1 1 3 3 3 1 SNARE associated Golgi protein 7tm_1 PF00001.16 EER24256.1 - 0.0005 19.2 1.5 0.003 16.7 1.0 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF872 PF05915.7 EER24256.1 - 0.017 15.0 0.7 0.26 11.1 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF1049 PF06305.6 EER24256.1 - 0.033 13.6 4.0 0.55 9.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PgaD PF13994.1 EER24256.1 - 0.042 13.3 0.0 0.042 13.3 0.0 2.5 2 1 0 2 2 2 0 PgaD-like protein DUF3552 PF12072.3 EER24256.1 - 0.11 11.6 0.2 0.17 11.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HAMP PF00672.20 EER24256.1 - 0.16 12.1 0.0 0.16 12.1 0.0 3.3 5 0 0 5 5 5 0 HAMP domain Yip1 PF04893.12 EER24256.1 - 0.44 10.0 20.2 1.7 8.0 0.5 2.2 2 0 0 2 2 2 0 Yip1 domain Romo1 PF10247.4 EER24256.1 - 0.48 10.6 3.7 28 5.0 1.4 2.7 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 DUF3693 PF12472.3 EER24256.1 - 0.6 9.7 3.9 0.83 9.2 0.6 2.6 2 0 0 2 2 2 0 Phage related protein Amino_oxidase PF01593.19 EER24257.1 - 2.3e-90 303.8 0.0 9.6e-90 301.8 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EER24257.1 - 1.9e-12 47.1 0.0 4.2e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EER24257.1 - 3.6e-07 30.1 0.0 9.3e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EER24257.1 - 0.0011 18.0 0.2 0.005 15.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EER24257.1 - 0.0012 18.6 0.6 0.38 10.5 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EER24257.1 - 0.0044 17.0 0.3 0.21 11.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HMG_box PF00505.14 EER24257.1 - 0.0048 17.1 1.5 0.015 15.5 1.0 1.9 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EER24257.1 - 0.015 15.6 0.5 0.039 14.3 0.4 1.7 1 0 0 1 1 1 0 HMG-box domain Pyr_redox_2 PF07992.9 EER24257.1 - 0.031 14.1 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EER24257.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain DUF1220 PF06758.8 EER24257.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) HI0933_like PF03486.9 EER24257.1 - 0.31 9.4 0.4 0.77 8.1 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein DUF3106 PF11304.3 EER24257.1 - 0.35 11.3 5.3 0.76 10.2 3.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Vps5 PF09325.5 EER24257.1 - 0.56 9.4 4.0 1 8.5 2.7 1.3 1 0 0 1 1 1 0 Vps5 C terminal like GIDA PF01134.17 EER24257.1 - 1 8.1 1.6 9.1 5.0 0.3 2.6 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EER24258.1 - 1.3e-26 93.7 0.0 2.2e-26 93.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER24258.1 - 1e-15 57.9 0.0 3.6e-13 49.7 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER24258.1 - 4.7e-08 33.3 0.1 4.2e-05 23.7 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER24258.1 - 2.4e-05 24.2 0.1 0.011 15.7 0.0 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EER24258.1 - 0.00015 20.9 0.1 0.00043 19.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 EER24258.1 - 0.00032 20.9 0.1 0.027 14.6 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EER24258.1 - 0.0015 18.6 0.2 1.6 8.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase K_oxygenase PF13434.1 EER24258.1 - 0.0057 15.6 0.0 0.36 9.6 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EER24258.1 - 0.0086 15.0 0.9 2.9 6.6 0.0 3.1 2 2 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EER24258.1 - 0.01 14.9 0.1 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 EER24258.1 - 0.014 14.2 3.8 0.18 10.5 0.1 2.7 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.17 EER24258.1 - 0.093 11.5 7.5 1.1 8.0 0.1 3.6 2 1 1 3 3 3 0 Glucose inhibited division protein A LEA_1 PF03760.10 EER24259.1 - 0.034 14.3 1.0 0.067 13.3 0.7 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 Peptidase_S8 PF00082.17 EER24260.1 - 9.7e-55 185.6 0.8 9.7e-55 185.6 0.6 1.6 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EER24260.1 - 4.2e-29 100.1 0.8 9.3e-29 99.0 0.6 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain Mito_fiss_reg PF05308.6 EER24260.1 - 0.51 9.6 8.6 0.027 13.8 1.4 1.9 2 0 0 2 2 2 0 Mitochondrial fission regulator PX PF00787.19 EER24261.1 - 2.1e-18 66.1 0.1 4.5e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EER24261.1 - 8.5e-12 44.8 7.9 1.1e-05 24.7 0.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF3140 PF11338.3 EER24261.1 - 0.033 14.2 0.3 0.13 12.3 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Occludin_ELL PF07303.8 EER24261.1 - 0.071 13.8 0.7 3.3 8.5 0.0 2.8 2 0 0 2 2 2 0 Occludin homology domain DUF1664 PF07889.7 EER24261.1 - 0.1 12.3 0.9 5 6.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DASH_Dad3 PF08656.5 EER24261.1 - 0.28 10.9 1.4 0.79 9.4 0.0 2.4 2 1 1 3 3 3 0 DASH complex subunit Dad3 BAR PF03114.13 EER24261.1 - 0.33 10.4 8.1 2.3 7.6 5.6 2.1 1 1 0 1 1 1 0 BAR domain DUF724 PF05266.9 EER24261.1 - 0.59 9.7 4.3 10 5.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) FAD_binding_3 PF01494.14 EER24262.1 - 1.4e-17 63.8 0.9 9.5e-16 57.7 0.6 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EER24262.1 - 0.0098 14.8 0.0 0.063 12.1 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 EER24262.1 - 0.01 14.6 0.0 0.017 13.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase K_oxygenase PF13434.1 EER24262.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EER24262.1 - 0.019 13.9 0.3 0.037 12.9 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EER24262.1 - 0.036 14.0 0.1 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER24262.1 - 0.049 13.4 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER24262.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EER24262.1 - 0.083 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EER24262.1 - 0.097 11.2 0.0 0.23 10.0 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase tRNA-synt_His PF13393.1 EER24263.1 - 3.2e-37 128.2 0.0 4.8e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EER24263.1 - 1.9e-18 66.6 0.0 3.5e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EER24263.1 - 1.3e-09 37.8 0.0 1.4e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EER24263.1 - 0.00031 19.6 0.0 0.026 13.3 0.0 2.6 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) APH PF01636.18 EER24264.1 - 3e-15 56.6 0.2 6.1e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER24264.1 - 7.2e-05 22.4 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EER24265.1 - 0.0002 21.1 0.2 0.00037 20.2 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_42M PF08532.5 EER24265.1 - 0.078 12.1 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain DNA_pol_E_B PF04042.11 EER24266.1 - 0.13 11.4 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B UCH PF00443.24 EER24268.1 - 5.9e-64 215.7 0.0 5.9e-64 215.7 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER24268.1 - 4.3e-28 98.5 0.3 2.4e-21 76.4 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase OmpH PF03938.9 EER24268.1 - 0.0031 17.4 6.6 0.0064 16.4 4.5 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) Peptidase_C98 PF15499.1 EER24268.1 - 0.0095 15.2 3.8 0.066 12.4 1.7 2.5 2 1 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ycf1 PF05758.7 EER24268.1 - 4.9 4.7 9.8 7.8 4.0 6.8 1.2 1 0 0 1 1 1 0 Ycf1 DUF2058 PF09831.4 EER24268.1 - 8.1 6.2 18.5 19 5.1 12.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Glyco_transf_22 PF03901.12 EER24269.1 - 2.7e-43 148.5 16.1 3.7e-43 148.0 11.2 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dynamitin PF04912.9 EER24270.1 - 5.4e-30 104.4 12.2 1.4e-15 56.9 4.5 2.2 2 0 0 2 2 2 2 Dynamitin Cob_adeno_trans PF01923.13 EER24270.1 - 0.012 15.3 9.6 4.4 7.0 0.9 3.3 3 0 0 3 3 3 0 Cobalamin adenosyltransferase TBPIP PF07106.8 EER24270.1 - 0.059 12.9 7.8 1.7 8.1 0.3 2.7 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EER24270.1 - 0.081 11.3 5.9 0.51 8.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DivIC PF04977.10 EER24270.1 - 0.083 12.3 16.8 0.11 11.9 1.8 3.6 3 0 0 3 3 3 0 Septum formation initiator ADIP PF11559.3 EER24270.1 - 0.14 12.0 15.3 5.2 6.9 0.1 3.4 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Cytochrom_B562 PF07361.6 EER24270.1 - 0.16 12.4 5.5 8.3 6.8 0.7 3.1 2 0 0 2 2 2 0 Cytochrome b562 Prefoldin_2 PF01920.15 EER24270.1 - 0.18 11.5 10.6 0.54 10.0 0.3 3.2 3 0 0 3 3 3 0 Prefoldin subunit SseC PF04888.7 EER24270.1 - 0.24 10.7 5.8 0.62 9.3 4.0 1.6 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family Spc24 PF08286.6 EER24270.1 - 0.28 10.8 12.7 0.81 9.3 2.9 2.9 3 0 0 3 3 2 0 Spc24 subunit of Ndc80 Fmp27_WPPW PF10359.4 EER24270.1 - 0.36 9.1 8.5 0.47 8.8 1.5 2.4 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.1 EER24270.1 - 0.39 9.8 12.3 1.1 8.4 3.5 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EER24270.1 - 0.4 11.0 8.4 4.2 7.7 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 EER24270.1 - 0.43 9.5 13.5 2 7.4 3.9 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4446 PF14584.1 EER24270.1 - 0.48 10.2 5.2 3.6 7.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4559 PF15112.1 EER24270.1 - 0.49 9.4 5.3 1.2 8.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) Viral_P18 PF04521.8 EER24270.1 - 5.3 6.4 12.9 5.8 6.3 0.8 3.3 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein COG2 PF06148.6 EER24270.1 - 5.8 6.7 11.2 1.2 9.0 0.7 2.9 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TPR_MLP1_2 PF07926.7 EER24270.1 - 7 6.4 17.4 0.54 10.0 1.3 3.3 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein GrpE PF01025.14 EER24270.1 - 8.3 5.9 13.6 2.9 7.3 2.2 2.8 3 0 0 3 3 3 0 GrpE Aldedh PF00171.17 EER24272.1 - 7.5e-135 449.8 0.7 9e-135 449.5 0.5 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Calreticulin PF00262.13 EER24273.1 - 4e-165 548.8 20.7 4e-165 548.8 14.4 2.0 2 0 0 2 2 2 2 Calreticulin family Aldolase_II PF00596.16 EER24274.1 - 1.3e-40 138.9 0.0 1.5e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Vps5 PF09325.5 EER24275.1 - 2.2e-89 298.7 6.6 3.5e-89 298.1 4.5 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EER24275.1 - 2.6e-25 88.4 0.0 7.7e-25 86.8 0.0 1.9 1 0 0 1 1 1 1 PX domain BAR PF03114.13 EER24275.1 - 0.43 10.0 8.6 1.2 8.5 6.0 1.6 1 1 0 1 1 1 0 BAR domain Ribosomal_L31 PF01197.13 EER24276.1 - 0.037 14.0 0.2 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L31 Flavin_Reduct PF01613.13 EER24277.1 - 1.9e-25 89.5 0.3 4.6e-25 88.2 0.2 1.7 1 1 0 1 1 1 1 Flavin reductase like domain TilS PF09179.6 EER24277.1 - 0.12 12.4 0.2 0.59 10.1 0.1 2.1 2 0 0 2 2 2 0 TilS substrate binding domain DUF1612 PF07756.7 EER24278.1 - 8.3 6.5 11.4 2.7 8.0 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1612) V_ATPase_I PF01496.14 EER24278.1 - 10 3.8 16.9 15 3.2 11.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 4HBT_2 PF13279.1 EER24279.1 - 8.9e-10 39.0 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Methyltransf_11 PF08241.7 EER24280.1 - 3.8e-07 30.4 0.0 7.2e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER24280.1 - 2.7e-06 27.6 0.0 4.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER24280.1 - 1.1e-05 25.2 0.0 3.7e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER24280.1 - 0.00025 20.2 0.0 0.00039 19.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EER24280.1 - 0.0011 18.9 0.0 0.0027 17.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER24280.1 - 0.0013 19.2 0.0 0.0031 18.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Exo_endo_phos PF03372.18 EER24281.1 - 3.2e-19 69.8 0.0 5.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EER24281.1 - 5.7e-15 54.5 12.0 1.8e-08 33.7 2.9 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER24281.1 - 2.7e-11 43.0 19.8 5.8e-08 32.3 5.7 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EER24281.1 - 1.4e-06 27.4 7.8 0.017 15.0 0.0 4.2 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EER24281.1 - 6.6e-06 25.5 8.0 0.15 12.3 0.0 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EER24281.1 - 0.17 12.0 0.1 0.17 12.0 0.1 4.2 6 0 0 6 6 6 0 Leucine Rich repeat MFS_1 PF07690.11 EER24282.1 - 4.9e-36 124.1 51.3 1.3e-35 122.7 35.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EER24282.1 - 3.1e-17 62.0 17.3 3.1e-17 62.0 12.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER24282.1 - 2.8e-10 39.3 15.5 2.8e-10 39.3 10.8 2.9 1 1 1 3 3 3 1 Sugar (and other) transporter Abhydrolase_6 PF12697.2 EER24283.1 - 7.8e-23 81.5 1.7 9.8e-23 81.2 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EER24283.1 - 2.8e-19 68.7 0.0 6.9e-19 67.4 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EER24283.1 - 6e-18 64.9 0.0 9.6e-18 64.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EER24283.1 - 4.2e-07 29.6 0.0 0.32 10.3 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EER24283.1 - 0.0013 17.7 0.0 0.0021 17.0 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 EER24283.1 - 0.0043 16.3 0.8 0.0078 15.5 0.1 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF1749 PF08538.5 EER24283.1 - 0.016 14.1 0.1 0.19 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_3 PF07859.8 EER24283.1 - 0.021 14.3 0.1 0.061 12.8 0.1 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EER24283.1 - 0.022 14.1 0.0 0.093 12.1 0.0 2.0 2 1 1 3 3 3 0 Putative esterase Chlorophyllase PF07224.6 EER24283.1 - 0.023 13.4 0.1 0.043 12.6 0.1 1.3 1 1 0 1 1 1 0 Chlorophyllase DUF915 PF06028.6 EER24283.1 - 0.054 12.5 0.1 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 EER24283.1 - 0.057 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 EER24283.1 - 0.49 9.9 3.8 0.72 9.3 1.8 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold GCD14 PF08704.5 EER24284.1 - 3.8e-05 23.3 0.0 0.019 14.4 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Metallophos PF00149.23 EER24285.1 - 1.6e-10 40.7 1.0 4.8e-10 39.1 0.7 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER24285.1 - 1.9e-05 24.5 0.1 4.2e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NAD_binding_1 PF00175.16 EER24286.1 - 9.1e-06 26.2 0.0 0.0057 17.2 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EER24286.1 - 0.0001 22.2 0.3 0.0034 17.2 0.2 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain MFS_2 PF13347.1 EER24289.1 - 0.00071 18.0 0.3 0.0023 16.4 0.0 1.9 2 1 0 2 2 2 1 MFS/sugar transport protein Baculo_11_kDa PF06143.6 EER24289.1 - 0.13 11.6 3.8 2.4 7.5 0.1 2.4 2 0 0 2 2 2 0 Baculovirus 11 kDa family E1-E2_ATPase PF00122.15 EER24290.1 - 2.9e-51 173.7 0.7 7.1e-51 172.4 0.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EER24290.1 - 3.6e-43 148.4 0.7 7e-43 147.5 0.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EER24290.1 - 2.3e-41 139.7 0.1 1.5e-09 37.8 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EER24290.1 - 3.8e-13 50.0 0.5 1.6e-12 48.0 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER24290.1 - 0.0004 20.0 0.8 0.0025 17.4 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2997 PF11211.3 EER24290.1 - 0.67 9.3 5.4 12 5.4 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2997) PCI PF01399.22 EER24291.1 - 1.3e-05 25.4 0.0 2.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 EER24292.1 - 6.8e-12 45.5 0.0 3.3e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.20 EER24293.1 - 1.2e-25 89.2 0.7 2.2e-25 88.3 0.5 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 EER24293.1 - 2.9e-09 36.8 0.1 5.2e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER24293.1 - 7.9e-09 35.5 0.2 1.6e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Rad1 PF02144.11 EER24294.1 - 1.9e-91 305.6 0.0 2.2e-91 305.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 SbcCD_C PF13558.1 EER24295.1 - 6.6e-12 45.1 0.0 2.1e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EER24295.1 - 0.00037 19.0 112.4 0.0018 16.8 12.5 5.7 1 1 4 5 5 5 4 AAA domain AAA_21 PF13304.1 EER24295.1 - 0.00085 19.3 0.0 0.00085 19.3 0.0 3.5 3 2 2 5 5 5 1 AAA domain PPP4R2 PF09184.6 EER24296.1 - 1.7e-10 40.9 0.0 1.7e-10 40.9 0.0 2.8 2 2 0 2 2 2 1 PPP4R2 DUF155 PF02582.9 EER24298.1 - 2.4e-59 200.1 0.0 3.6e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 zf-H2C2_2 PF13465.1 EER24299.1 - 1e-20 72.9 24.5 2.9e-07 30.4 0.9 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EER24299.1 - 1e-19 69.5 27.3 4e-05 23.6 1.2 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER24299.1 - 2.3e-12 46.3 26.7 0.00046 20.3 3.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EER24299.1 - 1.2e-05 25.2 8.5 0.14 12.3 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EER24299.1 - 0.035 14.3 14.6 0.42 10.8 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EER24299.1 - 0.051 13.4 17.5 1.1 9.2 0.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 EER24299.1 - 0.12 12.1 0.4 0.12 12.1 0.3 2.9 4 0 0 4 4 4 0 XPA protein N-terminal C1_1 PF00130.17 EER24299.1 - 1 9.1 6.3 0.5 10.1 0.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 EER24299.1 - 6.3 6.8 12.0 32 4.5 0.1 3.8 2 1 2 4 4 4 0 Zinc ribbon domain Methyltransf_23 PF13489.1 EER24300.1 - 1.1e-17 64.1 0.0 1.9e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER24300.1 - 5.9e-12 45.9 0.0 1.2e-11 44.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER24300.1 - 9.1e-12 45.3 0.0 3.1e-10 40.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER24300.1 - 2.7e-10 40.8 0.0 4.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER24300.1 - 3.6e-07 29.8 0.0 0.00053 19.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EER24300.1 - 8.8e-07 29.2 0.0 1.9e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER24300.1 - 1.9e-05 24.6 0.0 8.6e-05 22.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EER24300.1 - 0.015 14.4 0.0 4.5 6.2 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase NodS PF05401.6 EER24300.1 - 0.11 11.9 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.12 EER24300.1 - 0.16 10.8 0.0 0.33 9.8 0.0 1.5 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family p450 PF00067.17 EER24301.1 - 6.2e-75 252.4 0.0 7.1e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 EER24302.1 - 6.9e-67 224.8 2.0 1.3e-66 223.8 1.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EER24302.1 - 2.4e-34 118.4 3.8 2.4e-34 118.4 2.6 2.3 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EER24302.1 - 1.1e-27 97.8 0.0 2.3e-26 93.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER24302.1 - 1.8e-23 82.2 0.0 3.9e-23 81.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EER24302.1 - 1.1e-11 43.9 0.1 3.3e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EER24302.1 - 1.4e-11 44.8 0.0 7.1e-11 42.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER24302.1 - 6.3e-06 25.9 0.6 0.0005 19.7 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PPP4R2 PF09184.6 EER24302.1 - 0.016 14.7 1.1 0.027 14.0 0.8 1.3 1 0 0 1 1 1 0 PPP4R2 BRAP2 PF07576.7 EER24303.1 - 5.2e-25 87.1 0.0 9.7e-25 86.2 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EER24303.1 - 7e-21 74.1 3.5 2e-20 72.6 2.5 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EER24303.1 - 3.3e-09 36.4 9.8 3.3e-09 36.4 6.8 3.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EER24303.1 - 0.00014 21.4 7.6 0.00014 21.4 5.3 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EER24303.1 - 0.00092 18.8 8.6 0.00092 18.8 5.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER24303.1 - 0.001 18.6 5.7 0.001 18.6 3.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER24303.1 - 0.0012 18.7 9.7 0.0012 18.7 6.7 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EER24303.1 - 0.0018 18.3 4.9 0.0018 18.3 3.4 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EER24303.1 - 0.0039 16.9 1.8 0.0039 16.9 1.3 2.4 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EER24303.1 - 0.0068 16.1 2.8 0.0068 16.1 1.9 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-Apc11 PF12861.2 EER24303.1 - 0.0093 15.7 5.5 0.023 14.5 3.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger ApoO PF09769.4 EER24303.1 - 0.031 14.0 0.3 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein O DUF2205 PF10224.4 EER24303.1 - 0.13 11.8 4.2 5.9 6.5 0.2 2.5 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) CCDC155 PF14662.1 EER24303.1 - 0.19 11.2 12.9 0.33 10.5 8.9 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Prok-RING_4 PF14447.1 EER24303.1 - 0.2 11.2 5.8 6.1 6.4 2.0 3.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FUSC PF04632.7 EER24303.1 - 0.26 9.6 3.8 0.35 9.2 2.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Baculo_RING PF05883.6 EER24303.1 - 0.31 10.8 2.0 0.79 9.5 1.4 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EER24303.1 - 1.4 8.5 6.5 4.8 6.8 4.5 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_MLP1_2 PF07926.7 EER24303.1 - 3.8 7.2 16.6 6.5 6.4 11.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EER24303.1 - 8 5.3 14.3 13 4.6 9.9 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 ubiquitin PF00240.18 EER24304.1 - 7.2e-136 441.7 24.5 1.1e-33 114.4 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EER24304.1 - 1.3e-77 255.4 22.7 5.6e-19 67.6 0.6 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EER24304.1 - 5.3e-24 84.2 11.9 0.00016 21.8 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EER24304.1 - 3.2e-21 75.7 1.5 0.0012 18.5 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing DUF2407 PF10302.4 EER24304.1 - 5.6e-14 52.0 2.5 0.11 12.7 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EER24304.1 - 8.9e-14 51.3 3.5 0.13 12.1 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EER24304.1 - 1.3e-10 41.1 0.0 1.5 8.8 0.0 4.7 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 EER24304.1 - 2.1e-06 27.0 0.7 1.4 8.0 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 EER24304.1 - 4.6e-06 26.2 5.5 6.8 6.5 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain IGR PF09597.5 EER24304.1 - 1.4e-05 24.8 0.3 24 4.8 0.0 4.3 4 0 0 4 4 4 0 IGR protein motif Big_3_3 PF13750.1 EER24304.1 - 2.4e-05 23.7 0.1 19 4.6 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) TUG-UBL1 PF11470.3 EER24304.1 - 3e-05 23.8 6.9 7.8 6.4 0.1 4.2 4 0 0 4 4 4 0 GLUT4 regulating protein TUG ACT_4 PF13291.1 EER24304.1 - 0.0024 18.1 0.7 1.1e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 ACT domain USP7_C2 PF14533.1 EER24304.1 - 0.0032 16.9 5.1 5.6 6.3 0.3 3.8 1 1 0 2 2 2 2 Ubiquitin-specific protease C-terminal Plexin_cytopl PF08337.7 EER24304.1 - 0.0039 15.5 14.0 3.6 5.7 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 EER24304.1 - 0.0096 16.0 5.7 56 3.9 0.0 4.4 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Sortase PF04203.8 EER24304.1 - 0.021 14.4 2.5 37 3.9 0.0 3.9 2 1 2 4 4 4 0 Sortase family Tash_PEST PF07708.6 EER24304.1 - 0.026 14.4 29.1 3.5 7.7 1.2 4.4 4 0 0 4 4 4 0 Tash protein PEST motif CTDII PF01556.13 EER24304.1 - 0.038 13.8 16.6 6.6 6.7 0.3 4.5 1 1 3 4 4 4 0 DnaJ C terminal domain GABP-alpha PF11620.3 EER24304.1 - 0.051 13.5 7.8 47 4.0 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 EER24304.1 - 0.97 9.4 7.8 1.2e+02 2.7 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 EER24304.1 - 1.1 9.4 14.8 57 3.8 0.2 5.9 4 4 0 4 4 4 0 FERM N-terminal domain Zn_clus PF00172.13 EER24305.1 - 0.003 17.4 8.4 0.0074 16.1 5.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.16 EER24306.1 - 9.2e-38 127.4 30.9 2.7e-10 39.6 0.7 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EER24306.1 - 1e-25 90.3 0.0 1.8e-16 60.5 0.0 4.0 1 1 2 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EER24306.1 - 0.0075 16.2 0.0 0.15 12.0 0.0 3.0 3 1 0 3 3 3 1 Prenyltransferase-like dsrm PF00035.20 EER24307.1 - 5.8e-05 23.5 0.0 0.0001 22.8 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EER24307.1 - 0.0038 17.4 0.1 0.0075 16.5 0.1 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DEAD PF00270.24 EER24309.1 - 3.1e-42 143.9 0.0 6.5e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EER24309.1 - 1.6e-21 75.6 0.0 3e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EER24309.1 - 8.5e-21 73.6 0.0 1.8e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TRP PF06011.7 EER24310.1 - 1.1e-156 521.8 26.6 1.3e-156 521.5 18.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EER24310.1 - 1.3e-41 141.9 0.1 2e-41 141.3 0.1 1.3 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 EER24310.1 - 0.0031 16.8 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycoprotein UL132 zf-U1 PF06220.7 EER24311.1 - 3.1e-06 26.6 1.0 4.2e-06 26.2 0.7 1.2 1 0 0 1 1 1 1 U1 zinc finger Actin PF00022.14 EER24313.1 - 4.7e-131 436.8 0.0 5.3e-131 436.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EER24313.1 - 0.15 10.5 0.0 1.9 6.9 0.0 2.5 1 1 0 1 1 1 0 MreB/Mbl protein Glyco_tran_28_C PF04101.11 EER24314.1 - 1.9e-18 66.6 0.0 4.4e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EER24314.1 - 0.0056 15.9 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 EER24314.1 - 0.012 14.2 0.1 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase MRP-S28 PF10213.4 EER24315.1 - 6e-43 145.9 0.0 1.1e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein p47_phox_C PF08944.6 EER24316.1 - 0.16 12.2 1.5 0.92 9.7 0.1 2.5 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain zf-PHD-like PF15446.1 EER24317.1 - 3.7e-69 231.4 8.6 6.9e-69 230.5 6.0 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EER24317.1 - 9.2e-59 198.6 0.1 1.4e-58 198.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER24317.1 - 1.1e-13 50.8 0.0 2.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EER24317.1 - 1.7e-08 33.6 0.6 3.2e-08 32.7 0.4 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EER24317.1 - 2e-07 31.0 0.0 1.7e-06 27.9 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Chromo PF00385.19 EER24317.1 - 2e-05 24.1 8.4 0.015 14.9 1.3 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EER24317.1 - 5.6e-05 22.7 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 EER24317.1 - 0.0001 21.9 13.9 0.00026 20.6 1.8 4.2 3 1 0 3 3 3 1 PHD-finger DEAD_2 PF06733.10 EER24317.1 - 0.0051 16.2 0.0 0.013 14.8 0.0 1.7 1 0 0 1 1 1 1 DEAD_2 SnAC PF14619.1 EER24317.1 - 0.0075 16.4 3.3 0.11 12.7 0.1 2.9 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Prok-RING_1 PF14446.1 EER24317.1 - 0.0086 15.7 2.4 0.0086 15.7 1.7 2.8 3 1 1 4 4 3 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EER24317.1 - 0.014 14.7 0.5 0.014 14.7 0.4 3.3 4 0 0 4 4 4 0 PHD-finger DUF1087 PF06465.8 EER24317.1 - 0.048 13.5 1.8 0.14 12.1 0.3 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) AAA_22 PF13401.1 EER24317.1 - 0.055 13.6 0.0 0.31 11.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain SpoU_methylase PF00588.14 EER24318.1 - 3.1e-27 95.1 0.0 6.3e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EER24318.1 - 2.2e-12 46.9 0.0 4.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding SNF2_N PF00176.18 EER24319.1 - 1.9e-82 276.4 0.5 3.1e-82 275.7 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EER24319.1 - 6.3e-45 151.7 2.2 6.3e-45 151.7 1.5 2.6 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 EER24319.1 - 6.4e-35 119.9 1.8 6.4e-35 119.9 1.3 4.0 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 EER24319.1 - 2.8e-14 52.7 0.0 1.1e-13 50.8 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER24319.1 - 5.1e-08 32.9 0.0 3.9e-07 30.0 0.0 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EER24319.1 - 1.6e-05 24.4 0.0 4.6e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4588 PF15251.1 EER24320.1 - 0.00029 20.9 9.6 0.00065 19.7 6.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) gerPA PF10676.4 EER24320.1 - 0.0048 16.7 0.8 0.32 10.8 0.2 2.6 2 0 0 2 2 2 2 Spore germination protein gerPA/gerPF Adap_comp_sub PF00928.16 EER24321.1 - 1.1e-50 172.2 0.0 1.7e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EER24321.1 - 0.00039 20.1 0.0 0.00061 19.5 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Aldedh PF00171.17 EER24322.1 - 1.4e-77 261.0 0.0 1.7e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Acetyltransf_3 PF13302.1 EER24323.1 - 2.4e-29 102.3 0.0 3.7e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER24323.1 - 0.084 12.9 0.2 6.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EER24323.1 - 0.1 12.5 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EER24324.1 - 2.7e-61 206.9 0.0 3.5e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24324.1 - 1.1e-35 122.9 0.0 1.5e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER24324.1 - 6.4e-05 22.0 0.0 0.0001 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER24324.1 - 0.0035 17.1 0.0 0.24 11.0 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EER24324.1 - 0.045 13.1 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EER24324.1 - 0.076 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 SH2_2 PF14633.1 EER24325.1 - 6.3e-85 283.7 0.0 6.3e-85 283.7 0.0 2.3 3 0 0 3 3 3 1 SH2 domain DLD PF14878.1 EER24325.1 - 1.7e-36 124.8 5.1 1.7e-36 124.8 3.5 3.4 3 0 0 3 3 2 1 Death-like domain of SPT6 HHH_7 PF14635.1 EER24325.1 - 1.6e-30 105.2 0.1 3.2e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EER24325.1 - 2.9e-29 101.5 0.0 1.2e-28 99.5 0.0 2.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EER24325.1 - 5.6e-23 80.9 24.1 5.6e-23 80.9 16.7 5.9 6 0 0 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EER24325.1 - 4e-19 68.7 5.0 1.3e-17 63.9 3.5 3.0 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EER24325.1 - 4.3e-05 23.2 0.0 0.00014 21.6 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EER24325.1 - 4.3e-05 23.3 0.0 0.0013 18.6 0.0 2.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif S1 PF00575.18 EER24325.1 - 0.0022 18.0 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 S1 RNA binding domain B12-binding PF02310.14 EER24325.1 - 0.072 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain Antiterm PF03589.8 EER24325.1 - 0.11 12.5 0.4 9 6.4 0.0 2.7 2 0 0 2 2 2 0 Antitermination protein IFRD PF05004.8 EER24326.1 - 4.8e-31 107.9 0.4 7.3e-31 107.3 0.3 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DUF3782 PF12644.2 EER24327.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) FdhD-NarQ PF02634.10 EER24327.1 - 0.1 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 FdhD/NarQ family DUF605 PF04652.11 EER24328.1 - 5.5 6.2 19.4 7.8 5.7 13.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF1083 PF06452.6 EER24329.1 - 0.0061 16.4 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1083) MFS_1 PF07690.11 EER24330.1 - 9.9e-47 159.3 24.2 9.9e-47 159.3 16.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER24330.1 - 5.9e-17 61.3 0.9 5.9e-17 61.3 0.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.11 EER24330.1 - 0.00027 19.7 0.1 0.0004 19.2 0.1 1.2 1 0 0 1 1 1 1 BT1 family TRI12 PF06609.8 EER24330.1 - 0.00057 18.2 2.0 0.00082 17.6 1.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gly_kinase PF02595.10 EER24331.1 - 3.3e-114 381.5 5.2 3.7e-114 381.3 3.6 1.0 1 0 0 1 1 1 1 Glycerate kinase family ABC2_membrane PF01061.19 EER24332.1 - 1.6e-74 249.5 70.6 5.8e-41 139.9 20.1 4.6 4 1 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 EER24332.1 - 1.6e-38 132.0 0.0 2.3e-18 66.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EER24332.1 - 5e-31 106.4 11.7 1.6e-26 91.9 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EER24332.1 - 1.2e-21 76.6 0.0 3e-21 75.2 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EER24332.1 - 1.1e-08 34.7 0.2 1e-05 25.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain ABC2_membrane_3 PF12698.2 EER24332.1 - 8.5e-07 28.3 19.4 8.5e-07 28.3 13.4 3.3 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_33 PF13671.1 EER24332.1 - 2.8e-06 27.2 0.1 0.0013 18.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EER24332.1 - 2.2e-05 23.6 0.1 0.00087 18.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EER24332.1 - 3.4e-05 23.2 1.3 0.0015 18.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EER24332.1 - 0.00049 20.9 0.0 0.036 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EER24332.1 - 0.00049 20.1 0.0 0.31 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EER24332.1 - 0.00074 19.5 0.1 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EER24332.1 - 0.00084 19.6 0.1 0.038 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EER24332.1 - 0.0011 18.4 2.8 0.0014 18.1 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EER24332.1 - 0.0024 18.0 0.5 0.17 12.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EER24332.1 - 0.0079 15.4 0.2 0.083 12.1 0.0 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EER24332.1 - 0.02 14.8 0.0 7.4 6.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 EER24332.1 - 0.025 14.2 3.8 0.94 9.1 0.2 2.8 3 0 0 3 3 2 0 NACHT domain AAA_28 PF13521.1 EER24332.1 - 0.042 13.7 0.1 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EER24332.1 - 0.062 12.9 2.4 1.1 8.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EER24332.1 - 0.1 12.0 0.1 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EER24332.1 - 0.14 11.9 1.6 7.7 6.3 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 EER24332.1 - 0.17 10.7 0.1 3.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EER24332.1 - 0.17 11.4 0.7 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EER24332.1 - 0.2 11.9 0.1 0.2 11.9 0.1 1.9 2 0 0 2 2 1 0 AAA domain Miro PF08477.8 EER24332.1 - 0.25 11.8 0.1 3.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AAA_15 PF13175.1 EER24332.1 - 0.44 9.5 0.0 2.1 7.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AMP-binding PF00501.23 EER24333.1 - 1.5e-72 244.3 0.0 1.9e-72 243.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER24333.1 - 5e-13 49.7 0.0 1.3e-12 48.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cutinase PF01083.17 EER24336.1 - 3e-36 124.8 0.0 3.4e-36 124.6 0.0 1.0 1 0 0 1 1 1 1 Cutinase uDENN PF03456.13 EER24337.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 uDENN domain DUF4066 PF13278.1 EER24338.1 - 0.00016 20.9 0.1 0.00022 20.5 0.1 1.2 1 0 0 1 1 1 1 Putative amidotransferase DIT1_PvcA PF05141.7 EER24339.1 - 3.6e-87 292.2 0.0 4.5e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 EER24340.1 - 4.9e-57 193.4 0.0 5.7e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2623 PF11115.3 EER24340.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) MFS_1 PF07690.11 EER24341.1 - 8.7e-36 123.3 40.0 8.7e-36 123.3 27.8 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EER24341.1 - 5.4e-10 38.4 26.8 1.7e-09 36.8 18.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter CoA_transf_3 PF02515.12 EER24342.1 - 2.5e-36 124.7 0.0 1.7e-33 115.4 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III RPAP1_C PF08620.5 EER24343.1 - 9.2e-27 92.7 0.0 1.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EER24343.1 - 3e-18 65.1 3.5 5e-18 64.4 2.4 1.4 1 0 0 1 1 1 1 RPAP1-like, N-terminal HUN PF08729.5 EER24344.1 - 6.9e-14 51.4 0.0 2.1e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Phosphoesterase PF04185.9 EER24345.1 - 7.3e-76 255.7 0.7 1.1e-75 255.1 0.5 1.2 1 0 0 1 1 1 1 Phosphoesterase family Cu-oxidase_3 PF07732.10 EER24346.1 - 5e-45 152.0 0.4 1.6e-42 143.9 0.0 3.8 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EER24346.1 - 1.6e-32 111.9 3.9 2.1e-30 105.0 0.4 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EER24346.1 - 1.9e-15 57.0 0.0 1.9e-14 53.8 0.0 2.4 2 1 0 2 2 2 1 Multicopper oxidase CDC45 PF02724.9 EER24346.1 - 0.044 11.8 1.9 0.055 11.5 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EER24346.1 - 0.054 11.4 0.4 0.071 11.0 0.3 1.1 1 0 0 1 1 1 0 Nop14-like family Apc1 PF12859.2 EER24347.1 - 1.2e-27 96.1 0.3 3.4e-27 94.7 0.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EER24347.1 - 0.00017 21.6 7.1 0.44 10.8 0.0 5.1 5 0 0 5 5 5 3 Proteasome/cyclosome repeat PIP5K PF01504.13 EER24349.1 - 2e-84 282.6 0.3 2e-84 282.6 0.2 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Zip PF02535.17 EER24349.1 - 9.6 5.1 15.4 1.8 7.4 8.1 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Linker_histone PF00538.14 EER24350.1 - 1e-22 79.9 0.2 2.9e-22 78.5 0.1 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family Peptidase_M35 PF02102.10 EER24352.1 - 1.7e-82 277.0 2.1 2e-82 276.7 1.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EER24352.1 - 9.2e-10 39.2 0.2 2.1e-09 38.0 0.1 1.6 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase Peptidase_M91 PF14891.1 EER24352.1 - 0.031 14.3 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 Effector protein Kdo PF06293.9 EER24353.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EER24353.1 - 0.025 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Dicty_CAR PF05462.6 EER24354.1 - 7.3e-11 41.5 10.7 7.3e-11 41.5 7.4 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EER24354.1 - 1.3e-07 31.0 0.3 1.7e-07 30.6 0.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 EER24354.1 - 3e-07 30.1 9.6 4.9e-07 29.5 6.7 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.19 EER24354.1 - 0.0032 16.5 8.0 0.0049 15.9 5.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) XPG_I PF00867.13 EER24355.1 - 3.6e-31 107.0 0.3 8.7e-31 105.8 0.0 1.8 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EER24355.1 - 1.3e-19 70.3 0.4 4.9e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EER24355.1 - 2e-05 24.7 2.0 4.6e-05 23.5 0.0 2.5 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold TniB PF05621.6 EER24355.1 - 0.02 13.6 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein HXXSHH PF07586.6 EER24355.1 - 0.19 10.6 3.5 0.36 9.6 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Glyoxalase_4 PF13669.1 EER24356.1 - 7.4e-05 22.7 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EER24356.1 - 0.0056 16.6 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain Acyl-CoA_dh_N PF02771.11 EER24357.1 - 3.7e-25 88.7 0.1 7.6e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EER24357.1 - 9.6e-24 84.1 0.7 1.4e-23 83.6 0.1 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EER24357.1 - 1.3e-16 59.8 0.0 3.2e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EER24357.1 - 4.1e-08 33.5 0.4 7.9e-08 32.6 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UQ_con PF00179.21 EER24358.1 - 2.4e-51 172.8 0.0 2.7e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER24358.1 - 6.8e-05 22.6 0.0 7.9e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EER24358.1 - 0.0053 16.6 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EER24358.1 - 0.021 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Glyoxalase_2 PF12681.2 EER24359.1 - 2.5e-09 37.6 0.0 4.8e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EER24359.1 - 0.024 14.5 0.0 0.26 11.2 0.0 2.5 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4106 PF13388.1 EER24359.1 - 0.072 12.0 5.3 0.15 11.0 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Gly-zipper_Omp PF13488.1 EER24359.1 - 0.086 12.4 5.0 0.18 11.4 3.5 1.5 1 0 0 1 1 1 0 Glycine zipper EMG1 PF03587.9 EER24360.1 - 1.1e-77 259.9 0.0 1.3e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Acetyltransf_13 PF13880.1 EER24361.1 - 7.5e-28 96.0 0.0 1.9e-27 94.7 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EER24361.1 - 1.4e-16 59.7 0.1 2.6e-16 58.9 0.1 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO eIF2A PF08662.6 EER24364.1 - 1.4e-83 279.3 0.1 1.2e-82 276.3 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EER24364.1 - 1.7e-05 24.5 0.5 1.5 8.7 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CDV3 PF15359.1 EER24364.1 - 0.03 14.3 0.2 0.03 14.3 0.2 4.5 4 1 1 5 5 5 0 Carnitine deficiency-associated protein 3 DPPIV_N PF00930.16 EER24364.1 - 0.03 12.8 0.0 2.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region NAD_binding_6 PF08030.7 EER24365.1 - 1.5e-32 112.6 0.0 7.2e-32 110.4 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EER24365.1 - 2.2e-22 78.8 0.0 5e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EER24365.1 - 1.2e-16 60.8 11.0 1.2e-16 60.8 7.6 2.4 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EER24365.1 - 1.8e-05 24.7 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EER24365.1 - 0.051 14.1 0.0 0.69 10.5 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain DUF4131 PF13567.1 EER24365.1 - 4.8 6.5 13.4 0.11 11.9 4.2 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) CorA PF01544.13 EER24366.1 - 2e-16 59.8 0.6 3.9e-16 58.9 0.4 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TFIID_20kDa PF03847.8 EER24367.1 - 3.2e-21 75.3 0.0 7.2e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Hid1 PF12722.2 EER24367.1 - 3.1 5.3 19.5 4.9 4.7 13.5 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Baculo_PP31 PF05311.6 EER24367.1 - 5.2 6.2 17.3 11 5.1 12.0 1.5 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) DASH_Spc34 PF08657.5 EER24368.1 - 4.7e-49 167.4 8.1 2.5e-47 161.7 5.6 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 ISG65-75 PF11727.3 EER24368.1 - 0.0023 17.0 0.4 0.003 16.6 0.3 1.2 1 0 0 1 1 1 1 Invariant surface glycoprotein DUF465 PF04325.8 EER24368.1 - 0.008 15.8 1.1 0.018 14.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF465) MAD PF05557.8 EER24368.1 - 0.026 12.6 6.5 0.048 11.7 4.5 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF1978 PF09321.5 EER24368.1 - 0.048 13.0 4.6 0.073 12.4 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) CENP-F_leu_zip PF10473.4 EER24368.1 - 0.099 12.5 3.9 1.5 8.6 0.6 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 EER24368.1 - 0.1 12.4 5.5 0.15 11.8 0.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DASH_Spc19 PF08287.6 EER24368.1 - 0.26 10.9 3.7 0.51 9.9 2.6 1.5 1 0 0 1 1 1 0 Spc19 Seryl_tRNA_N PF02403.17 EER24368.1 - 0.37 10.8 2.6 1.6 8.7 0.1 2.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 EER24368.1 - 0.48 9.3 3.9 0.55 9.1 2.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EER24368.1 - 1.2 9.5 5.8 3.1 8.2 0.3 2.9 2 1 1 3 3 3 0 SlyX DivIC PF04977.10 EER24368.1 - 1.3 8.5 4.4 8.3 5.9 0.3 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.1 EER24368.1 - 4.7 7.7 9.4 11 6.5 0.9 2.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Rpn3_C PF08375.6 EER24369.1 - 1.3e-25 89.5 1.0 4.5e-25 87.8 0.7 2.0 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EER24369.1 - 1.7e-20 73.2 0.4 1.7e-19 70.0 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.12 EER24369.1 - 0.02 14.7 0.0 0.062 13.2 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EER24369.1 - 0.023 14.4 0.2 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 polyprenyl_synt PF00348.12 EER24370.1 - 5.8e-49 166.2 0.1 4.2e-46 156.9 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase Ank PF00023.25 EER24371.1 - 1.3e-29 100.4 3.8 9.7e-07 28.2 0.1 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EER24371.1 - 1.5e-28 98.9 5.4 1.6e-12 47.5 0.2 3.3 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER24371.1 - 8.2e-24 83.5 0.6 1.9e-08 34.5 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER24371.1 - 2.8e-22 78.2 7.1 1.2e-07 31.7 0.1 3.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER24371.1 - 5e-18 63.4 4.4 0.0018 18.2 0.1 5.6 5 0 0 5 5 5 4 Ankyrin repeat DUF349 PF03993.7 EER24371.1 - 0.15 12.2 2.5 0.24 11.5 1.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) BPL_LplA_LipB PF03099.14 EER24372.1 - 3.1e-09 36.9 0.0 6.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.17 EER24373.1 - 3.3e-53 179.4 0.0 3.8e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER24373.1 - 3.8e-16 59.6 0.0 5.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER24373.1 - 1.9e-08 33.7 0.0 2.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER24373.1 - 8.3e-05 21.8 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EER24373.1 - 0.0045 16.2 0.0 0.0061 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EER24373.1 - 0.027 13.1 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EER24373.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EER24373.1 - 0.092 12.2 0.0 1.4 8.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EER24373.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase IpgD PF05925.7 EER24373.1 - 0.15 10.2 0.0 0.18 10.0 0.0 1.1 1 0 0 1 1 1 0 Enterobacterial virulence protein IpgD CWC25 PF12542.3 EER24374.1 - 1.1e-27 96.3 0.8 1.1e-27 96.3 0.6 3.6 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EER24374.1 - 2.3e-12 46.7 8.4 2.3e-12 46.7 5.8 2.9 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF3674 PF12426.3 EER24374.1 - 0.12 11.8 0.6 0.42 10.0 0.1 2.1 2 0 0 2 2 2 0 RNA dependent RNA polymerase PCI PF01399.22 EER24375.1 - 2.2e-18 66.4 0.1 6.5e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EER24375.1 - 1.2e-06 28.3 0.4 2.6e-06 27.2 0.3 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_10 PF13374.1 EER24375.1 - 0.0003 20.6 0.2 0.12 12.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EER24375.1 - 0.0026 17.4 2.3 0.095 12.5 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER24375.1 - 0.0044 16.5 2.8 0.03 13.9 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EER24375.1 - 0.012 15.4 5.9 0.024 14.5 0.1 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Ipi1_N PF12333.3 EER24375.1 - 0.017 15.1 0.1 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_12 PF13424.1 EER24375.1 - 0.021 14.7 3.4 0.19 11.6 0.2 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EER24375.1 - 0.1 12.4 0.1 0.1 12.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EER24375.1 - 0.12 13.0 0.2 0.55 10.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EER24375.1 - 0.21 11.2 4.3 0.3 10.7 0.2 3.2 3 2 0 3 3 3 0 TPR repeat Peptidase_C65 PF10275.4 EER24376.1 - 3.7e-64 216.4 0.0 4.4e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain Pyridox_oxidase PF01243.15 EER24377.1 - 3.8e-13 49.2 0.0 1.3e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase NIPSNAP PF07978.8 EER24378.1 - 8.3e-38 128.4 0.3 9.8e-28 96.1 0.0 2.3 2 0 0 2 2 2 2 NIPSNAP SR-25 PF10500.4 EER24378.1 - 0.16 11.4 15.3 0.31 10.5 10.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 EER24378.1 - 1.4 8.9 12.3 2.3 8.2 8.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF2217 PF10265.4 EER24378.1 - 3.4 6.3 6.7 4.7 5.8 4.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF755 PF05501.6 EER24378.1 - 6.2 6.9 19.3 2.3 8.2 11.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF755) CDP-OH_P_transf PF01066.16 EER24379.1 - 3e-15 56.3 5.8 3e-15 56.3 4.0 3.3 4 1 0 4 4 4 1 CDP-alcohol phosphatidyltransferase DUF308 PF03729.8 EER24379.1 - 0.072 13.0 0.7 0.072 13.0 0.5 3.6 4 1 0 4 4 4 0 Short repeat of unknown function (DUF308) Ribosomal_S27e PF01667.12 EER24380.1 - 5.8e-29 99.4 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EER24380.1 - 0.0081 16.0 1.3 0.009 15.8 0.9 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EER24380.1 - 0.12 11.9 0.7 0.22 11.0 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger FSH1 PF03959.8 EER24381.1 - 6.2e-66 221.8 0.0 1.9e-65 220.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EER24381.1 - 3e-08 33.8 2.8 5.5e-08 32.9 1.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER24381.1 - 4e-05 23.4 0.0 6.1e-05 22.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PCI PF01399.22 EER24382.1 - 1.9e-20 73.0 0.0 7.5e-20 71.2 0.0 2.0 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EER24382.1 - 0.02 14.6 0.1 0.079 12.7 0.0 2.0 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 TP_methylase PF00590.15 EER24383.1 - 6.9e-46 156.5 0.2 1.1e-45 155.9 0.2 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EER24383.1 - 1.5e-13 50.8 0.0 2.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EER24383.1 - 5e-10 38.5 0.0 3.6e-08 32.5 0.0 2.3 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EER24383.1 - 0.0022 16.9 0.0 0.0044 15.9 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central GRP PF07172.6 EER24384.1 - 0.042 14.3 8.4 0.04 14.3 5.8 1.1 1 0 0 1 1 1 0 Glycine rich protein family DUF3357 PF11837.3 EER24385.1 - 0.006 16.4 0.1 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) DUF2973 PF11189.3 EER24385.1 - 0.048 13.4 0.8 0.58 9.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) OSTbeta PF15048.1 EER24385.1 - 0.049 13.6 0.0 0.091 12.8 0.0 1.4 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein 60KD_IMP PF02096.15 EER24385.1 - 0.05 13.2 0.2 0.068 12.8 0.2 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Melittin PF01372.12 EER24386.1 - 1.5 8.2 3.9 49 3.3 0.1 3.1 3 0 0 3 3 3 0 Melittin ABC_tran PF00005.22 EER24387.1 - 4.8e-46 156.4 0.0 2.3e-22 79.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EER24387.1 - 2.1e-28 99.5 8.2 2.1e-28 99.5 5.7 3.2 3 1 0 3 3 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EER24387.1 - 4.9e-13 49.7 0.2 0.0053 16.7 0.0 4.4 3 1 1 4 4 4 3 AAA domain AAA_22 PF13401.1 EER24387.1 - 5.8e-11 42.6 0.3 0.00084 19.4 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EER24387.1 - 2.8e-10 40.4 0.8 1.9e-05 24.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EER24387.1 - 2.1e-09 36.9 5.7 0.034 13.3 0.1 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EER24387.1 - 5.6e-07 29.5 0.1 7.1e-05 22.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EER24387.1 - 1.7e-06 27.1 0.1 0.0033 16.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EER24387.1 - 2.5e-06 26.9 0.9 0.045 13.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EER24387.1 - 7e-06 26.2 0.0 0.0062 16.7 0.0 3.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EER24387.1 - 1.2e-05 25.2 0.0 0.11 12.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EER24387.1 - 1.2e-05 24.9 0.6 0.0055 16.4 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EER24387.1 - 2.5e-05 23.8 4.2 0.085 12.2 0.1 3.9 4 0 0 4 4 4 2 AAA-like domain DUF258 PF03193.11 EER24387.1 - 3.2e-05 23.1 0.2 0.072 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EER24387.1 - 3.5e-05 24.2 0.4 0.41 11.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EER24387.1 - 7.6e-05 23.5 2.2 0.11 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EER24387.1 - 0.00022 20.7 0.6 0.073 12.5 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EER24387.1 - 0.0003 21.1 0.3 0.084 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EER24387.1 - 0.00031 21.0 0.1 0.6 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 EER24387.1 - 0.00032 20.3 0.3 0.042 13.4 0.0 2.9 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EER24387.1 - 0.00035 20.0 1.5 0.34 10.2 0.0 3.1 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.7 EER24387.1 - 0.00036 19.7 0.1 0.1 11.6 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.14 EER24387.1 - 0.00036 20.0 2.0 0.023 14.1 0.1 2.7 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EER24387.1 - 0.00043 20.0 0.6 0.042 13.5 0.0 3.1 3 1 0 3 3 2 1 Archaeal ATPase AAA_19 PF13245.1 EER24387.1 - 0.00089 18.9 0.2 0.0057 16.3 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain GTP_EFTU PF00009.22 EER24387.1 - 0.0018 17.7 0.0 0.72 9.2 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EER24387.1 - 0.0023 17.7 2.4 0.062 13.1 0.0 2.9 3 0 0 3 3 3 1 Dynamin family DUF87 PF01935.12 EER24387.1 - 0.0033 17.2 2.3 0.024 14.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 EER24387.1 - 0.0053 16.6 0.2 2.3 8.1 0.1 3.0 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit TrwB_AAD_bind PF10412.4 EER24387.1 - 0.0058 15.3 0.1 1 7.9 0.0 2.6 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 EER24387.1 - 0.012 15.2 1.3 0.26 10.9 0.0 2.8 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 EER24387.1 - 0.015 15.0 1.4 0.83 9.3 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EER24387.1 - 0.018 14.9 0.1 1.6 8.6 0.0 3.6 4 0 0 4 4 3 0 AAA domain PduV-EutP PF10662.4 EER24387.1 - 0.02 14.3 0.8 0.11 11.9 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EER24387.1 - 0.023 14.3 0.5 3.3 7.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EER24387.1 - 0.031 13.2 0.1 7.8 5.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.13 EER24387.1 - 0.042 12.8 0.1 0.75 8.7 0.0 2.1 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.12 EER24387.1 - 0.045 13.2 0.6 0.87 9.0 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 EER24387.1 - 0.067 12.7 0.2 4 6.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EER24387.1 - 0.084 13.0 0.1 9.3 6.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.17 EER24387.1 - 0.15 10.8 5.8 0.087 11.6 0.1 2.9 3 1 0 3 3 3 0 NB-ARC domain Mg_chelatase PF01078.16 EER24387.1 - 0.17 11.0 0.1 1.8 7.6 0.0 2.4 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EER24387.1 - 0.18 11.3 0.1 5.9 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain DeoC PF01791.4 EER24388.1 - 2.1e-48 164.6 2.7 2.4e-48 164.4 1.9 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EER24388.1 - 0.02 13.8 0.3 0.03 13.3 0.2 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EER24388.1 - 0.043 13.0 0.1 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Methyltrn_RNA_3 PF02598.12 EER24389.1 - 2.5e-79 266.6 0.0 2.9e-79 266.4 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.14 EER24389.1 - 0.084 12.7 0.0 5 6.9 0.0 2.2 2 0 0 2 2 2 0 SpoU rRNA Methylase family WD40 PF00400.27 EER24390.1 - 1.5e-14 53.2 6.3 2.1e-07 30.5 0.0 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EER24390.1 - 0.017 13.9 4.7 0.053 12.2 1.1 2.4 2 1 0 2 2 2 0 Nup133 N terminal like IncA PF04156.9 EER24390.1 - 4.9 6.7 9.7 8.4 5.9 6.7 1.3 1 0 0 1 1 1 0 IncA protein Radical_SAM PF04055.16 EER24391.1 - 1.8e-15 57.5 0.0 2.8e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Phyto-Amp PF15438.1 EER24391.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma HAD PF12710.2 EER24392.1 - 6.3e-15 55.8 0.0 9.7e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EER24392.1 - 2.6e-10 41.0 0.1 1.6e-09 38.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER24392.1 - 4.2e-08 33.0 0.1 3.4e-07 30.1 0.1 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EER24392.1 - 4.4e-07 30.2 0.1 2.7e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EER24392.1 - 0.00016 20.8 0.0 0.00083 18.5 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 EER24392.1 - 0.025 13.5 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) PAPS_reduct PF01507.14 EER24393.1 - 3.3e-43 147.5 0.0 5.9e-43 146.6 0.0 1.4 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family ATP-sulfurylase PF01747.12 EER24394.1 - 3.2e-85 284.8 0.0 4.7e-85 284.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EER24394.1 - 1.2e-58 197.1 0.1 1.9e-58 196.5 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EER24394.1 - 1.8e-53 180.2 0.0 3.1e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.7 EER24394.1 - 0.056 13.0 0.0 0.25 10.9 0.0 2.0 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 EER24394.1 - 0.098 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 TPR_12 PF13424.1 EER24395.1 - 0.14 12.1 0.4 16 5.5 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AA_permease_2 PF13520.1 EER24396.1 - 2.7e-50 171.1 46.5 3.7e-50 170.7 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER24396.1 - 1.3e-25 89.7 42.5 1.7e-25 89.3 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease YlaH PF14036.1 EER24396.1 - 0.023 14.7 1.3 0.023 14.7 0.9 2.9 3 0 0 3 3 3 0 YlaH-like protein DUF4592 PF15262.1 EER24399.1 - 0.027 15.0 0.3 0.04 14.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Complex1_LYR_1 PF13232.1 EER24400.1 - 8.5e-18 64.3 6.6 1.1e-17 63.9 4.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EER24400.1 - 1.7e-16 59.7 6.1 2.4e-16 59.2 4.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) ALS2CR8 PF15299.1 EER24400.1 - 0.088 12.3 0.2 0.09 12.3 0.2 1.1 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 SET PF00856.23 EER24402.1 - 1.8e-18 67.3 0.5 1.8e-18 67.3 0.3 3.4 3 2 0 3 3 3 1 SET domain zf-DHHC PF01529.15 EER24403.1 - 6.9e-34 116.7 7.0 6.9e-34 116.7 4.9 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase PSI PF01437.20 EER24403.1 - 0.12 12.5 8.4 0.24 11.5 5.9 1.5 1 0 0 1 1 1 0 Plexin repeat PMT PF02366.13 EER24405.1 - 3.6e-78 262.3 18.2 3.6e-78 262.3 12.6 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EER24405.1 - 1.7e-56 190.8 0.1 4.3e-56 189.4 0.0 1.7 2 0 0 2 2 2 1 MIR domain Ubiquitin_2 PF14560.1 EER24405.1 - 0.032 14.4 0.1 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-like domain PRP21_like_P PF12230.3 EER24406.1 - 8.5e-65 218.4 13.7 8.6e-64 215.1 9.5 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EER24406.1 - 1.3e-39 133.6 2.8 3.4e-20 71.4 0.1 2.4 2 0 0 2 2 2 2 Surp module DUF1517 PF07466.6 EER24406.1 - 0.033 13.1 1.0 0.057 12.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Sec2p PF06428.6 EER24407.1 - 3.3e-26 91.0 14.0 3.3e-26 91.0 9.7 2.3 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p Myosin_tail_1 PF01576.14 EER24407.1 - 0.015 13.0 31.0 0.055 11.2 21.6 1.6 1 1 0 1 1 1 0 Myosin tail DUF3584 PF12128.3 EER24407.1 - 0.25 8.6 22.8 0.36 8.0 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) dsDNA_bind PF01984.15 EER24408.1 - 3.1e-35 120.3 10.6 3.8e-35 120.1 7.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EER24408.1 - 0.035 14.3 0.8 0.045 13.9 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4615) RelB_N PF12910.2 EER24408.1 - 0.093 12.1 0.1 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin stability system N-terminal Phostensin_N PF13916.1 EER24408.1 - 2.4 8.1 6.7 0.95 9.4 2.1 2.1 2 1 1 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal Coq4 PF05019.8 EER24409.1 - 2.3e-101 337.3 0.0 2.7e-101 337.1 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 EER24410.1 - 1e-20 74.6 0.0 2.2e-20 73.6 0.0 1.5 1 1 0 1 1 1 1 SET domain ApbA_C PF08546.6 EER24411.1 - 1.6e-33 115.3 0.5 2.4e-33 114.8 0.3 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EER24411.1 - 7.9e-27 93.5 0.1 5.3e-26 90.8 0.1 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.10 EER24412.1 - 3.8e-16 59.0 1.0 7.1e-16 58.1 0.7 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF2076 PF09849.4 EER24413.1 - 2.6e-07 30.9 9.0 3.1e-07 30.7 6.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EER24413.1 - 1.7e-06 27.7 2.2 3e-06 27.0 1.5 1.4 1 0 0 1 1 1 1 CHCH domain PAT1 PF09770.4 EER24413.1 - 5.6 5.0 9.2 6.6 4.8 6.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UBX PF00789.15 EER24414.1 - 1.2e-11 44.5 0.0 2.3e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 UBX domain Tox-GHH PF15636.1 EER24414.1 - 0.026 14.1 6.6 0.076 12.6 3.5 2.3 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin LAG1-DNAbind PF09271.6 EER24414.1 - 0.054 13.9 0.2 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 LAG1, DNA binding Amidase PF01425.16 EER24415.1 - 4.4e-74 249.9 0.0 6e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Amidase SURF1 PF02104.10 EER24416.1 - 1.6e-65 220.9 0.0 2.2e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 EER24417.1 - 4.8e-99 332.4 22.1 5.1e-98 329.0 15.3 2.0 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EER24417.1 - 1.1e-05 25.4 0.1 2.2e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EER24417.1 - 3e-05 24.0 0.0 7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EER24417.1 - 0.0028 17.7 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CMS1 PF14617.1 EER24418.1 - 1e-81 273.7 3.6 1.2e-81 273.4 2.5 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EER24418.1 - 0.00018 21.0 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AvrPtoB-E3_ubiq PF09046.5 EER24418.1 - 0.0066 16.4 0.2 2.1 8.3 0.1 2.3 2 0 0 2 2 2 2 AvrPtoB E3 ubiquitin ligase TT_ORF2 PF02957.10 EER24418.1 - 0.31 11.7 2.5 0.53 10.9 1.8 1.3 1 0 0 1 1 1 0 TT viral ORF2 RRM_1 PF00076.17 EER24419.1 - 2.5e-12 46.2 1.2 1e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER24419.1 - 1e-10 41.3 0.0 2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER24419.1 - 0.038 13.8 0.1 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2OG-FeII_Oxy_5 PF13759.1 EER24419.1 - 2.5 8.4 0.0 2.5 8.4 0.0 3.2 2 1 1 3 3 3 0 Putative 2OG-Fe(II) oxygenase Ras PF00071.17 EER24420.1 - 7.6e-55 184.7 0.0 8.7e-55 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER24420.1 - 1.6e-17 64.0 0.0 2.3e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER24420.1 - 4.2e-08 32.6 0.0 5.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MAM1 PF10434.4 EER24420.1 - 0.047 12.8 0.1 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex protein MAM1 ABM PF03992.11 EER24421.1 - 1e-09 38.3 0.0 3e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase RhoGAP PF00620.22 EER24422.1 - 2.7e-48 163.4 0.3 9.7e-48 161.6 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EER24422.1 - 7.9e-15 54.8 2.1 1.3e-14 54.1 0.2 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DMPK_coil PF08826.5 EER24422.1 - 4.6 7.2 7.7 3.7 7.5 0.6 3.1 2 1 1 3 3 3 0 DMPK coiled coil domain like SSF PF00474.12 EER24423.1 - 0.018 13.6 21.4 0.19 10.2 14.8 2.3 1 1 0 1 1 1 0 Sodium:solute symporter family MBA1 PF07961.6 EER24424.1 - 1.6e-05 23.8 0.0 2.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EER24424.1 - 8e-05 22.6 0.0 0.00019 21.4 0.0 1.6 1 1 0 1 1 1 1 Tim44-like domain EOS1 PF12326.3 EER24425.1 - 1.6e-29 102.4 14.4 4.7e-24 84.7 6.4 2.1 1 1 1 2 2 2 2 N-glycosylation protein ABC2_membrane_5 PF13346.1 EER24425.1 - 0.36 10.1 5.5 0.17 11.1 0.3 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein AmiS_UreI PF02293.10 EER24425.1 - 0.84 9.2 6.1 1 8.9 1.3 2.1 1 1 1 2 2 2 0 AmiS/UreI family transporter YesK PF14150.1 EER24425.1 - 2.4 8.3 5.9 1.4 9.0 1.0 2.6 2 1 0 2 2 2 0 YesK-like protein SUI1 PF01253.17 EER24426.1 - 9.7e-30 102.2 5.7 1.3e-29 101.8 3.9 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF520 PF04461.8 EER24426.1 - 0.12 12.2 3.4 0.14 11.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF520) Cas_Csa5 PF09702.5 EER24426.1 - 0.16 12.1 0.5 0.43 10.6 0.1 1.8 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) Img2 PF05046.9 EER24426.1 - 0.55 10.5 2.6 1.1 9.5 1.8 1.6 1 1 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) Apc5 PF12862.2 EER24427.1 - 3.3e-34 116.5 2.3 3.3e-34 116.5 1.6 3.4 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EER24427.1 - 0.0007 19.4 11.1 1.7 8.6 0.0 5.6 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EER24427.1 - 0.0014 18.8 0.4 0.51 10.7 0.1 3.8 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EER24427.1 - 0.0088 15.7 0.2 3.3 7.7 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 EER24427.1 - 0.029 14.3 5.6 0.59 10.0 0.4 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EER24427.1 - 0.28 11.7 5.5 4 8.1 0.1 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat SAICAR_synt PF01259.13 EER24428.1 - 6.6e-89 297.2 0.0 8.3e-89 296.9 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase CIA30 PF08547.7 EER24429.1 - 4.3e-37 127.3 0.0 6.1e-23 81.4 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) Med12 PF09497.5 EER24430.1 - 2.8e-27 94.4 0.2 7.7e-27 93.0 0.2 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DUF2404 PF10296.4 EER24431.1 - 6.2e-28 96.7 0.0 2.5e-27 94.8 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) ANTH PF07651.11 EER24432.1 - 1.1e-76 257.2 0.0 1.1e-76 257.2 0.0 2.8 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EER24432.1 - 3.8e-64 215.2 8.4 3.8e-64 215.2 5.8 6.1 3 2 5 8 8 8 1 I/LWEQ domain HMG_box PF00505.14 EER24434.1 - 1.7e-20 73.0 0.9 3e-20 72.2 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EER24434.1 - 1.7e-05 25.0 0.1 3e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain Exo_endo_phos PF03372.18 EER24435.1 - 6.6e-10 39.3 0.0 1.3e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EER24435.1 - 3.5e-09 36.3 0.0 1.6e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EER24435.1 - 6.1e-05 22.8 1.3 0.00016 21.5 0.9 1.8 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 EER24436.1 - 1.2e-47 160.6 1.1 1.2e-47 160.5 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Mannosyl_trans3 PF11051.3 EER24437.1 - 1e-48 166.0 0.0 1.3e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative MT0933_antitox PF14013.1 EER24438.1 - 0.1 12.7 3.4 0.21 11.7 2.4 1.6 1 0 0 1 1 1 0 MT0933-like antitoxin protein DUF1213 PF06740.7 EER24438.1 - 1.2 9.3 0.0 1.2 9.3 0.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1213) Methyltransf_23 PF13489.1 EER24440.1 - 3.9e-14 52.7 0.0 7.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER24440.1 - 9.9e-11 41.9 0.0 1.9e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER24440.1 - 1.5e-07 31.1 0.0 4.6e-07 29.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER24440.1 - 1.7e-07 31.6 0.0 1.1e-06 28.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER24440.1 - 2.2e-07 31.4 0.0 2.1e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER24440.1 - 0.0002 21.6 0.0 0.00044 20.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EER24440.1 - 0.0026 16.8 0.0 0.0043 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EER24440.1 - 0.0052 16.1 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EER24440.1 - 0.026 14.5 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EER24440.1 - 0.034 13.2 0.0 0.2 10.7 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 EER24440.1 - 0.064 11.5 0.1 0.36 9.0 0.1 1.9 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DNA_pol_B PF00136.16 EER24441.1 - 3.8e-92 309.5 0.0 5.6e-92 308.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EER24441.1 - 3.8e-24 85.1 0.1 5.3e-12 45.2 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EER24441.1 - 2.8e-20 72.0 7.2 2.8e-20 72.0 5.0 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DUF4612 PF15389.1 EER24441.1 - 0.68 10.5 3.7 0.37 11.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) Slu7 PF11708.3 EER24442.1 - 2.8e-78 262.9 20.9 2.8e-78 262.9 14.5 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EER24442.1 - 0.019 14.6 0.7 0.042 13.5 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L37e PF01907.14 EER24443.1 - 2e-28 97.9 11.5 3.1e-28 97.3 8.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EER24443.1 - 0.0019 17.9 1.5 0.003 17.3 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF35_N PF12172.3 EER24443.1 - 0.2 11.6 3.2 0.36 10.8 2.2 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_6 PF14599.1 EER24443.1 - 0.22 11.3 2.3 0.33 10.7 1.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon GFA PF04828.9 EER24443.1 - 0.33 10.9 4.1 4.9 7.1 0.6 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L40e PF01020.12 EER24443.1 - 4.6 6.9 9.0 16 5.1 0.1 2.5 1 1 1 2 2 2 0 Ribosomal L40e family Ribosomal_S14 PF00253.16 EER24443.1 - 4.8 6.6 11.1 2.7 7.4 0.4 2.6 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e DUF2348 PF09807.4 EER24444.1 - 2.6e-10 39.8 0.0 3.6e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 EER24444.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 KaiC RdRP PF05183.7 EER24445.1 - 2.1e-189 631.0 0.0 3.1e-189 630.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EER24445.1 - 0.0011 18.5 0.0 0.0035 16.9 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.14 EER24446.1 - 3.8e-62 209.8 0.0 6.7e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EER24446.1 - 6.4e-35 119.6 0.0 1.5e-34 118.4 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Semialdhyde_dhC PF02774.13 EER24447.1 - 3.7e-33 114.9 0.0 4.8e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EER24447.1 - 5e-28 97.8 0.0 1e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ribosomal_S4e PF00900.15 EER24448.1 - 4.4e-32 109.5 0.3 8.1e-32 108.7 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EER24448.1 - 5.3e-19 67.7 4.9 1.2e-18 66.6 3.4 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EER24448.1 - 3.4e-05 23.1 0.0 6.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EER24448.1 - 0.0077 15.9 0.7 0.0077 15.9 0.5 3.2 4 0 0 4 4 4 1 KOW motif RasGEF PF00617.14 EER24449.1 - 0.00048 19.8 0.0 0.00095 18.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain Myb_DNA-bind_6 PF13921.1 EER24450.1 - 1e-14 54.3 0.0 3.7e-07 30.1 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER24450.1 - 4.7e-10 39.3 0.7 0.00038 20.4 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PX PF00787.19 EER24451.1 - 1.9e-26 92.0 0.1 2.3e-26 91.8 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EER24451.1 - 0.062 12.3 0.0 0.077 12.0 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus WD40 PF00400.27 EER24452.1 - 1.1e-24 85.3 16.7 6e-08 32.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EER24452.1 - 1.5e-05 23.5 0.4 1.4 7.0 0.0 4.1 3 1 1 4 4 4 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EER24452.1 - 0.0048 17.1 0.3 10 6.5 0.0 3.7 4 0 0 4 4 4 2 PQQ-like domain Nucleoporin_N PF08801.6 EER24452.1 - 0.066 11.9 0.1 2.2 6.9 0.0 2.9 2 1 0 2 2 2 0 Nup133 N terminal like DUF2457 PF10446.4 EER24452.1 - 0.53 8.9 12.9 0.8 8.3 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EER24452.1 - 6.1 6.0 11.3 9.3 5.4 7.8 1.2 1 0 0 1 1 1 0 SDA1 SecE PF00584.15 EER24453.1 - 4.3e-12 45.4 0.0 5.2e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex RRM_6 PF14259.1 EER24454.1 - 3.8e-09 36.3 0.0 6.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER24454.1 - 7e-06 25.5 0.0 1.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER24454.1 - 0.0024 17.6 0.1 0.0045 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pyr_redox_3 PF13738.1 EER24455.1 - 1.1e-25 90.8 0.1 2.1e-25 89.9 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER24455.1 - 1.2e-11 43.5 0.1 1.7e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EER24455.1 - 3.8e-11 43.2 0.0 2.2e-10 40.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EER24455.1 - 2.3e-08 33.3 0.1 4.5e-07 29.0 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EER24455.1 - 1.7e-05 24.0 0.1 0.0007 18.7 0.3 2.4 1 1 1 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EER24455.1 - 1.8e-05 24.6 0.0 5.4e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EER24455.1 - 8.3e-05 22.9 0.4 0.78 10.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EER24455.1 - 0.00016 20.3 0.1 0.0011 17.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EER24455.1 - 0.00019 20.3 0.6 0.0038 16.1 0.1 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EER24455.1 - 0.00034 19.5 3.2 0.0041 16.0 0.9 2.3 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EER24455.1 - 0.0004 19.5 0.2 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EER24455.1 - 0.00062 18.9 0.3 0.003 16.7 0.0 2.1 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.7 EER24455.1 - 0.0017 17.3 0.3 0.0041 16.0 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EER24455.1 - 0.0048 16.4 0.3 0.047 13.2 0.1 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EER24455.1 - 0.0088 14.9 0.1 0.03 13.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EER24455.1 - 0.029 13.4 0.4 0.029 13.4 0.3 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EER24455.1 - 0.06 13.1 0.0 5 6.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EER24455.1 - 0.084 12.9 0.4 11 6.1 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DBD_Tnp_Mut PF03108.10 EER24456.1 - 3.4e-13 48.9 0.0 6.3e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 MuDR family transposase E7 PF00527.13 EER24456.1 - 0.061 13.4 0.1 0.099 12.8 0.1 1.3 1 0 0 1 1 1 0 E7 protein, Early protein Mito_carr PF00153.22 EER24457.1 - 1.2e-76 252.5 1.4 8.1e-25 86.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1049 PF06305.6 EER24457.1 - 0.033 13.6 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Ribosomal_L21e PF01157.13 EER24458.1 - 9.2e-40 134.4 6.6 9.2e-40 134.4 4.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e Ribosomal_S4 PF00163.14 EER24459.1 - 8.6e-30 102.9 3.0 9e-30 102.9 1.3 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EER24459.1 - 5.8e-14 51.2 1.8 5.8e-14 51.2 1.3 2.3 3 0 0 3 3 3 1 S4 domain BLOC1_2 PF10046.4 EER24460.1 - 0.0013 18.8 2.4 0.013 15.5 0.9 3.0 3 0 0 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 EzrA PF06160.7 EER24460.1 - 0.0067 14.6 4.4 0.015 13.5 2.6 1.8 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA FemAB PF02388.11 EER24460.1 - 0.011 14.4 1.7 0.011 14.4 1.2 1.5 2 0 0 2 2 2 0 FemAB family APP_amyloid PF10515.4 EER24460.1 - 0.018 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 beta-amyloid precursor protein C-terminus AAA_13 PF13166.1 EER24460.1 - 0.019 13.4 2.4 0.027 12.9 1.7 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 EER24460.1 - 0.079 11.6 6.3 0.042 12.4 0.7 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.5 EER24460.1 - 0.1 12.7 0.7 0.34 11.0 0.5 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FTO_CTD PF12934.2 EER24460.1 - 0.11 12.1 0.2 0.2 11.2 0.1 1.4 1 0 0 1 1 1 0 FTO C-terminal domain Cob_adeno_trans PF01923.13 EER24460.1 - 0.11 12.2 5.2 0.39 10.4 0.9 2.3 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Prefoldin PF02996.12 EER24460.1 - 0.15 11.7 8.9 0.21 11.2 1.2 3.5 2 1 2 4 4 4 0 Prefoldin subunit Fmp27_WPPW PF10359.4 EER24460.1 - 0.19 10.1 7.0 0.063 11.6 1.4 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ATG16 PF08614.6 EER24460.1 - 0.32 10.8 13.2 2.1 8.1 3.6 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 EER24460.1 - 0.36 10.6 3.9 0.9 9.3 1.0 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EER24460.1 - 0.41 10.5 4.3 0.34 10.8 0.8 2.4 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 EER24460.1 - 0.49 10.2 12.1 1 9.1 8.4 1.6 1 0 0 1 1 1 0 Tropomyosin like Reo_sigmaC PF04582.7 EER24460.1 - 0.62 9.1 5.7 0.35 9.9 2.1 1.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EER24460.1 - 0.64 8.9 12.5 0.092 11.6 2.8 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4407 PF14362.1 EER24460.1 - 1 8.2 8.8 2.9 6.7 6.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF972 PF06156.8 EER24460.1 - 1 9.7 7.3 5.9 7.2 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EER24460.1 - 1.1 8.7 6.1 9.4 5.6 0.1 3.2 2 1 1 3 3 3 0 Phage minor structural protein GP20 HlyD PF00529.15 EER24460.1 - 1.3 8.2 15.9 0.24 10.6 0.8 2.2 1 1 1 2 2 2 0 HlyD family secretion protein MscS_porin PF12795.2 EER24460.1 - 1.7 7.9 19.8 4.2 6.6 9.6 2.8 2 1 1 3 3 2 0 Mechanosensitive ion channel porin domain ISG65-75 PF11727.3 EER24460.1 - 1.9 7.4 5.0 1.8 7.5 0.2 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein FUSC PF04632.7 EER24460.1 - 3.1 6.1 6.2 4.5 5.5 4.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family CDC37_N PF03234.9 EER24460.1 - 3.5 7.8 5.9 4 7.7 2.9 1.9 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding IncA PF04156.9 EER24460.1 - 4.7 6.7 17.5 1.3 8.6 7.3 2.6 2 1 1 3 3 2 0 IncA protein DUF1409 PF07197.7 EER24460.1 - 5.5 7.1 10.7 15 5.7 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1409) Uds1 PF15456.1 EER24460.1 - 5.5 7.0 14.4 7.1 6.6 2.1 2.6 1 1 1 2 2 2 0 Up-regulated During Septation MIP-T3 PF10243.4 EER24461.1 - 7.3e-05 21.4 41.0 9.1e-05 21.1 28.4 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Amidoligase_2 PF12224.3 EER24462.1 - 7.6e-19 68.3 0.0 3.6e-11 43.1 0.0 3.0 2 1 0 2 2 2 2 Putative amidoligase enzyme DOPA_dioxygen PF08883.6 EER24463.1 - 3.6e-33 113.7 0.0 4.3e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF946 PF06101.6 EER24464.1 - 2.4e-13 48.9 1.1 5.9e-13 47.6 0.4 1.7 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EER24464.1 - 0.12 12.1 0.8 0.19 11.4 0.6 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Septin PF00735.13 EER24465.1 - 1.8e-28 99.4 0.0 1.5e-10 40.5 0.0 3.2 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 EER24465.1 - 0.005 16.3 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EER24465.1 - 0.021 14.6 0.0 0.11 12.2 0.0 2.2 3 0 0 3 3 3 0 Dynamin family MMR_HSR1 PF01926.18 EER24465.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EER24465.1 - 0.059 13.3 0.0 0.34 10.8 0.0 2.2 3 0 0 3 3 3 0 AAA ATPase domain Miro PF08477.8 EER24465.1 - 0.14 12.6 0.0 0.41 11.1 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein Annexin PF00191.15 EER24466.1 - 2e-13 50.0 2.4 0.079 12.8 0.0 5.2 4 1 0 4 4 4 4 Annexin TRF PF08558.5 EER24467.1 - 0.098 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) UPF0016 PF01169.14 EER24468.1 - 5.1e-42 141.8 24.4 7.3e-21 74.1 5.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 DUF2208 PF09973.4 EER24468.1 - 0.001 18.3 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2208) TerC PF03741.11 EER24468.1 - 0.0043 16.5 1.1 0.0051 16.2 0.0 1.7 2 0 0 2 2 2 1 Integral membrane protein TerC family DUF3357 PF11837.3 EER24468.1 - 1.1 9.1 6.7 1.3 8.8 0.2 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) Selenoprotein_S PF06936.6 EER24469.1 - 0.19 11.2 1.8 0.42 10.1 1.2 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) MFS_1 PF07690.11 EER24471.1 - 3.3e-37 128.0 30.4 4.3e-37 127.6 18.2 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER24471.1 - 2.2e-15 56.1 4.1 2.2e-15 56.1 2.9 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EER24471.1 - 1.2e-05 23.7 3.8 2.3e-05 22.8 2.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Gln-synt_C PF00120.19 EER24472.1 - 7.8e-43 146.4 0.0 1.7e-42 145.3 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EER24472.1 - 8.1e-25 87.8 0.0 1.7e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Acetyltransf_7 PF13508.1 EER24473.1 - 2.1e-09 37.4 0.0 6.5e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER24473.1 - 4.9e-06 26.4 0.0 1.2e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EER24473.1 - 0.00017 21.4 0.0 0.00085 19.1 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER24473.1 - 0.0006 19.9 0.0 0.0047 17.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain US2 PF02476.10 EER24473.1 - 0.038 14.4 0.3 0.084 13.3 0.2 1.6 1 1 0 1 1 1 0 US2 family FR47 PF08445.5 EER24473.1 - 0.093 12.5 0.0 0.34 10.7 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein Porin_1 PF00267.16 EER24473.1 - 0.099 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Gram-negative porin Acetyltransf_1 PF00583.19 EER24474.1 - 0.0013 18.6 1.0 0.0028 17.6 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EER24474.1 - 0.0026 17.5 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER24474.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER24474.1 - 0.036 14.1 0.1 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER24474.1 - 0.14 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein DUF2235 PF09994.4 EER24475.1 - 5e-91 304.9 0.2 6.2e-91 304.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Aldedh PF00171.17 EER24476.1 - 2e-155 517.6 0.1 2.2e-155 517.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pectinesterase PF01095.14 EER24476.1 - 0.068 11.7 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase DMRL_synthase PF00885.14 EER24476.1 - 0.07 12.7 0.0 0.21 11.2 0.0 1.8 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase AA_permease_2 PF13520.1 EER24477.1 - 8.3e-40 136.6 53.2 1e-39 136.2 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER24477.1 - 3.2e-21 75.2 49.2 4.4e-21 74.7 34.1 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_18 PF00704.23 EER24478.1 - 1e-20 74.5 0.1 1.7e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GPI2 PF06432.6 EER24480.1 - 6.7e-116 386.5 2.6 8.1e-116 386.2 1.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF346 PF03984.8 EER24481.1 - 2.5e-24 84.4 53.4 6.6e-06 25.4 0.6 7.3 7 0 0 7 7 7 7 Repeat of unknown function (DUF346) Toxin_42 PF15522.1 EER24481.1 - 2.8e-05 23.4 0.0 24 4.0 0.0 6.3 7 0 0 7 7 7 0 Putative toxin 42 Stap_Strp_toxin PF01123.15 EER24481.1 - 0.0018 18.6 0.0 2.1 8.9 0.0 4.7 5 1 2 7 7 7 1 Staphylococcal/Streptococcal toxin, OB-fold domain DUF1724 PF08350.5 EER24481.1 - 0.0022 17.5 2.6 24 4.5 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1724) Toxin_47 PF15527.1 EER24481.1 - 0.033 13.9 4.6 44 3.8 0.0 5.0 5 1 0 6 6 6 0 Putative toxin 47 DUF2510 PF10708.4 EER24481.1 - 0.053 12.9 62.9 0.058 12.8 0.2 6.8 7 0 0 7 7 7 0 Protein of unknown function (DUF2510) DUF3912 PF13051.1 EER24481.1 - 0.91 9.3 4.6 95 2.8 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function (DUF3912) Fumble PF03630.9 EER24482.1 - 3.8e-135 450.1 0.1 4.3e-134 446.6 0.1 1.9 1 1 0 1 1 1 1 Fumble Glyoxal_oxid_N PF07250.6 EER24483.1 - 2.2e-41 141.5 0.0 1.7e-40 138.6 0.0 2.2 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EER24483.1 - 5.7e-20 71.2 0.0 1.1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Chitin_bind_1 PF00187.14 EER24483.1 - 5.1e-05 23.1 20.3 9.4e-05 22.3 14.1 1.4 1 0 0 1 1 1 1 Chitin recognition protein RCC1_2 PF13540.1 EER24483.1 - 0.0085 15.6 2.1 0.087 12.4 0.0 3.3 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat DEAD PF00270.24 EER24484.1 - 1.7e-42 144.8 0.0 9.4e-42 142.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER24484.1 - 1.1e-20 73.2 0.2 1.1e-20 73.2 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EER24484.1 - 7.5e-05 21.6 0.0 0.00011 21.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EER24484.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EER24484.1 - 0.075 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Acetyltransf_1 PF00583.19 EER24485.1 - 9.7e-06 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EER24485.1 - 0.00036 20.7 0.0 0.00055 20.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER24485.1 - 0.00076 19.5 0.0 0.0014 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER24485.1 - 0.0016 18.5 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 EER24486.1 - 1.8e-45 155.3 17.0 3.5e-45 154.4 11.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER24486.1 - 6.1e-19 67.9 23.9 6.3e-19 67.8 15.7 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Polysacc_deac_1 PF01522.16 EER24487.1 - 1.8e-21 76.0 0.0 4e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EER24487.1 - 0.037 12.9 0.0 0.077 11.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Med11 PF10280.4 EER24487.1 - 0.08 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Mediator complex protein DFP PF04127.10 EER24488.1 - 2.5e-13 50.0 0.0 2.8e-05 23.8 0.0 3.4 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Ribosomal_60s PF00428.14 EER24488.1 - 1.1 9.6 6.7 2.5 8.5 4.7 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein S1-like PF14444.1 EER24489.1 - 0.21 11.3 0.2 0.38 10.5 0.2 1.4 1 0 0 1 1 1 0 S1-like Cor1 PF04803.7 EER24490.1 - 0.3 10.8 8.4 0.26 11.0 1.8 2.4 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region CytochromB561_N PF09786.4 EER24490.1 - 3.8 5.8 8.4 0.09 11.2 0.6 1.8 2 0 0 2 2 2 0 Cytochrome B561, N terminal CENP-O PF09496.5 EER24491.1 - 1.7e-30 105.0 0.1 3.3e-30 104.1 0.1 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acatn PF13000.2 EER24492.1 - 1.3e-153 512.5 24.8 9.6e-78 262.0 6.6 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.17 EER24493.1 - 6.7e-54 183.1 0.0 8.2e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EER24494.1 - 3.4e-21 75.6 0.0 5.2e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER24494.1 - 3.9e-12 46.0 0.0 2.2e-11 43.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER24494.1 - 1.8e-11 44.6 0.0 2.4e-10 40.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER24494.1 - 1.6e-08 34.9 0.0 3.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER24494.1 - 1.1e-07 32.1 0.0 2.6e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER24494.1 - 8.8e-07 29.2 0.0 3.7e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER24494.1 - 6.6e-05 22.9 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER24494.1 - 0.00045 19.3 0.0 0.0067 15.5 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EER24494.1 - 0.0028 16.7 0.0 0.011 14.7 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EER24494.1 - 0.022 13.8 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EER24494.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EER24494.1 - 0.025 13.9 0.0 0.26 10.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain TRM PF02005.11 EER24494.1 - 0.042 12.7 0.0 0.064 12.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF938 PF06080.7 EER24494.1 - 0.044 13.3 0.0 0.094 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) GidB PF02527.10 EER24494.1 - 0.15 11.1 0.0 8.6 5.4 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G STAG PF08514.6 EER24495.1 - 3.3e-37 126.7 0.3 1.1e-36 125.1 0.2 1.9 1 0 0 1 1 1 1 STAG domain DUF422 PF04240.7 EER24495.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF422) UreD PF01774.12 EER24496.1 - 2.5e-52 177.4 0.0 3.3e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 UreD urease accessory protein S1 PF00575.18 EER24499.1 - 1.6e-80 265.1 24.0 4.8e-16 58.6 0.1 12.3 12 0 0 12 12 12 10 S1 RNA binding domain Suf PF05843.9 EER24499.1 - 2.5e-07 30.7 9.3 0.00073 19.3 0.0 4.9 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EER24499.1 - 7.9e-07 29.5 0.0 0.033 14.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EER24499.1 - 4.2e-06 26.9 0.0 0.31 11.7 0.1 4.7 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER24499.1 - 9e-06 25.9 0.0 0.24 11.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat EXOSC1 PF10447.4 EER24499.1 - 0.013 15.4 1.9 1.9 8.4 0.1 4.8 4 1 0 4 4 4 0 Exosome component EXOSC1/CSL4 PPR PF01535.15 EER24499.1 - 0.046 13.6 0.0 6.5 6.9 0.0 3.3 2 1 0 2 2 2 0 PPR repeat TPR_12 PF13424.1 EER24499.1 - 0.051 13.5 0.0 4.7 7.2 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EER24499.1 - 0.23 11.4 0.3 42 4.4 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 EER24500.1 - 2.5e-23 81.0 9.7 4.3e-07 29.5 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EER24500.1 - 0.093 13.0 0.0 16 5.9 0.0 3.2 2 0 0 2 2 2 0 PQQ-like domain Cpn60_TCP1 PF00118.19 EER24501.1 - 7.2e-143 476.7 13.9 8.2e-143 476.5 9.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 EER24502.1 - 2.1e-21 76.2 0.1 3.4e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EER24502.1 - 1.4e-20 72.9 3.7 3.6e-20 71.6 1.8 2.1 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EER24502.1 - 1.3e-13 50.6 0.0 5.4e-13 48.6 0.0 2.1 3 0 0 3 3 3 1 Anticodon binding domain NARP1 PF12569.3 EER24502.1 - 2.4 6.8 5.9 4 6.0 4.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNase_PH PF01138.16 EER24504.1 - 1.5e-24 86.7 0.0 4.7e-24 85.1 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 PEMT PF04191.8 EER24505.1 - 5.1e-56 187.3 16.5 2.9e-36 123.7 0.5 3.0 3 0 0 3 3 3 2 Phospholipid methyltransferase ParA PF10609.4 EER24506.1 - 1.1e-35 121.2 0.0 2.2e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EER24506.1 - 2.1e-15 56.6 0.0 3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EER24506.1 - 1.9e-05 24.6 0.0 0.00012 22.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EER24506.1 - 2.1e-05 23.7 0.1 0.00086 18.4 0.0 2.6 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EER24506.1 - 0.00062 18.9 0.0 0.0011 18.1 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ DUF258 PF03193.11 EER24506.1 - 0.0044 16.2 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EER24506.1 - 0.021 14.2 0.1 0.033 13.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_26 PF13500.1 EER24506.1 - 0.033 13.7 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EER24506.1 - 0.074 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Ras PF00071.17 EER24506.1 - 0.091 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Ras family AAA_17 PF13207.1 EER24506.1 - 0.099 13.4 0.0 0.14 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EER24506.1 - 0.11 11.4 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EER24506.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EER24506.1 - 0.13 12.3 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.13 EER24506.1 - 0.16 11.1 0.0 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EER24506.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain SKG6 PF08693.5 EER24507.1 - 0.028 13.7 0.7 0.059 12.7 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EER24507.1 - 0.073 11.3 0.0 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2963 PF11178.3 EER24508.1 - 0.12 11.8 0.3 0.29 10.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2963) Asp PF00026.18 EER24509.1 - 8.5e-60 202.6 0.4 1e-59 202.3 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EER24509.1 - 9.9e-08 32.3 1.7 0.00019 21.8 0.5 2.9 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EER24509.1 - 0.00036 20.5 0.0 0.0016 18.4 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EER24509.1 - 0.051 13.1 0.1 0.25 10.8 0.1 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal tRNA_bind PF01588.15 EER24510.1 - 4.1e-20 71.4 5.1 1.9e-19 69.2 0.1 3.5 3 1 0 3 3 3 1 Putative tRNA binding domain GST_C_3 PF14497.1 EER24510.1 - 9.1e-08 32.5 0.0 2.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EER24510.1 - 9.5e-05 22.2 0.0 0.00033 20.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EER24510.1 - 0.01 15.7 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Anp1 PF03452.9 EER24511.1 - 1e-119 398.7 2.0 1.2e-119 398.4 0.0 1.8 2 0 0 2 2 2 1 Anp1 RR_TM4-6 PF06459.7 EER24511.1 - 0.14 12.0 11.1 0.22 11.3 7.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2036 PF09724.4 EER24512.1 - 3.2e-20 72.5 0.0 2.7e-14 53.0 0.0 2.0 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2036) Acetyltransf_7 PF13508.1 EER24513.1 - 1e-06 28.7 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER24513.1 - 2e-05 24.4 0.0 7.4e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER24513.1 - 0.00015 21.7 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EER24513.1 - 0.013 15.2 0.0 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_3 PF13302.1 EER24513.1 - 0.039 14.1 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER24513.1 - 0.056 13.5 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IBR PF01485.16 EER24514.1 - 1e-07 31.6 20.7 4.4e-07 29.6 5.7 3.8 3 1 0 3 3 3 2 IBR domain HORMA PF02301.13 EER24515.1 - 4.9e-22 78.4 0.0 7.5e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 HORMA domain IBN_N PF03810.14 EER24516.1 - 2.4e-07 30.5 4.3 6.3e-07 29.2 0.0 3.6 5 0 0 5 5 5 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EER24516.1 - 0.00013 21.9 2.6 0.0014 18.5 0.0 3.8 4 1 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 EER24516.1 - 0.025 14.6 1.9 22 5.4 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat Proteasom_PSMB PF10508.4 EER24516.1 - 0.041 12.1 0.0 0.15 10.3 0.0 1.8 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit Het-C PF07217.6 EER24517.1 - 4.8e-287 953.1 0.0 6.1e-287 952.7 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C zf-TRAF PF02176.13 EER24519.1 - 2e-07 31.2 34.8 0.00017 21.8 5.5 4.4 1 1 3 5 5 5 3 TRAF-type zinc finger zf-RING_5 PF14634.1 EER24519.1 - 7.1e-07 28.8 8.0 7.1e-07 28.8 5.5 3.3 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EER24519.1 - 1.5e-06 27.9 10.2 1.5e-06 27.9 7.1 3.5 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_4 PF15227.1 EER24519.1 - 8.5e-06 25.5 9.5 8.5e-06 25.5 6.6 2.8 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EER24519.1 - 2.8e-05 24.0 10.0 2.8e-05 24.0 6.9 3.2 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER24519.1 - 4.5e-05 23.0 7.6 4.5e-05 23.0 5.3 3.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER24519.1 - 7.7e-05 22.2 8.3 7.7e-05 22.2 5.8 3.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EER24519.1 - 0.00021 20.9 7.1 0.00072 19.2 4.9 2.1 1 0 0 1 1 1 1 RING-type zinc-finger Sina PF03145.11 EER24519.1 - 0.0035 17.0 15.7 0.042 13.5 1.0 2.9 1 1 1 3 3 3 2 Seven in absentia protein family DUF3138 PF11336.3 EER24519.1 - 0.12 10.5 0.9 0.19 9.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) zf-RING_3 PF14369.1 EER24519.1 - 0.15 12.0 9.6 0.59 10.1 0.1 4.5 4 0 0 4 4 4 0 zinc-finger Rubredoxin PF00301.15 EER24519.1 - 8.6 6.3 10.3 0.16 11.9 0.5 2.9 3 0 0 3 3 2 0 Rubredoxin SNARE PF05739.14 EER24520.1 - 4.1e-14 52.0 1.0 4.1e-14 52.0 0.7 2.2 3 0 0 3 3 3 1 SNARE domain FlxA PF14282.1 EER24520.1 - 0.0036 17.2 1.0 0.0036 17.2 0.7 2.2 2 0 0 2 2 2 1 FlxA-like protein LMBR1 PF04791.11 EER24520.1 - 0.15 10.5 0.1 0.18 10.3 0.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Fzo_mitofusin PF04799.8 EER24520.1 - 0.16 11.3 1.3 0.31 10.4 0.1 1.9 2 0 0 2 2 2 0 fzo-like conserved region DUF3275 PF11679.3 EER24520.1 - 0.23 11.0 2.5 0.37 10.3 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF4452 PF14618.1 EER24521.1 - 1.3e-72 243.0 8.9 1.3e-72 243.0 6.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4452) Peptidase_S21 PF00716.12 EER24521.1 - 0.035 13.4 0.1 0.063 12.5 0.1 1.4 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) Cyclin_N PF00134.18 EER24522.1 - 9.5e-13 47.8 0.1 9.2e-12 44.6 0.0 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Malectin PF11721.3 EER24522.1 - 0.082 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Di-glucose binding within endoplasmic reticulum Mito_carr PF00153.22 EER24523.1 - 1.5e-65 216.9 4.3 4.3e-24 84.0 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EER24523.1 - 9e-23 80.1 9.4 3.1e-14 52.8 0.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EER24523.1 - 2.8e-22 76.2 13.2 8e-07 27.9 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EER24523.1 - 4.6e-18 64.5 7.6 8.7e-10 38.0 0.6 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EER24523.1 - 9.9e-18 62.3 10.6 0.00012 21.6 0.2 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EER24523.1 - 1.3e-15 55.9 12.1 1.1e-06 27.7 0.5 3.8 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EER24523.1 - 4.2e-08 33.1 1.5 1.9e-05 24.6 0.2 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EER24523.1 - 0.014 15.1 4.8 0.37 10.5 0.3 2.6 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EER24523.1 - 0.045 13.4 2.0 18 5.1 0.0 3.2 3 0 0 3 3 3 0 EF hand GST_N_2 PF13409.1 EER24524.1 - 7.4e-21 73.9 0.0 1.8e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER24524.1 - 5.1e-14 51.9 0.0 1.2e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EER24524.1 - 8.6e-06 25.8 0.0 0.00025 21.2 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EER24524.1 - 0.0024 17.8 0.0 0.0044 16.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EER24524.1 - 0.0066 16.9 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ThiF PF00899.16 EER24525.1 - 3.5e-51 172.5 0.7 2.6e-31 108.2 0.0 2.7 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 EER24525.1 - 3.2e-40 135.5 2.3 2.9e-26 90.8 0.3 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EER24525.1 - 3.6e-38 130.5 0.0 1.1e-37 128.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EER24525.1 - 1.2e-23 82.2 2.7 7.6e-21 73.2 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EER24525.1 - 0.11 12.7 0.0 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Spc97_Spc98 PF04130.8 EER24526.1 - 2.8e-74 250.3 0.0 6.5e-74 249.1 0.0 1.6 2 1 0 2 2 2 1 Spc97 / Spc98 family MFS_1 PF07690.11 EER24527.1 - 2.9e-35 121.6 18.4 2.9e-35 121.6 12.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily 4HB_MCP_1 PF12729.2 EER24527.1 - 0.15 11.3 0.1 0.38 10.0 0.1 1.6 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction COX6A PF02046.10 EER24527.1 - 0.18 11.7 0.1 0.48 10.3 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa GILT PF03227.11 EER24529.1 - 8.6e-11 41.6 0.4 2.1e-10 40.4 0.2 1.8 1 1 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Hexokinase_1 PF00349.16 EER24530.1 - 9.5e-28 96.9 0.0 4.7e-26 91.3 0.0 2.8 1 1 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EER24530.1 - 3.8e-27 95.0 0.0 6.2e-22 77.9 0.0 2.2 2 0 0 2 2 2 2 Hexokinase TFIIA_gamma_C PF02751.9 EER24531.1 - 1.9e-27 94.7 2.1 2.6e-27 94.3 1.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EER24531.1 - 2.1e-26 91.2 0.2 3e-26 90.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Aldedh PF00171.17 EER24533.1 - 1.6e-134 448.7 0.0 1.8e-134 448.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EER24533.1 - 1.1e-06 27.7 0.2 5e-06 25.4 0.1 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EER24533.1 - 0.0064 15.7 0.1 0.13 11.4 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) BTV_NS2 PF04514.7 EER24534.1 - 0.017 14.0 4.4 0.027 13.3 3.0 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Methyltransf_33 PF10017.4 EER24536.1 - 3.1e-32 111.1 0.3 6.2e-32 110.1 0.2 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EER24536.1 - 2e-20 73.2 3.0 7e-10 38.6 0.3 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EER24536.1 - 1.1e-07 32.2 1.0 3.2e-07 30.7 0.7 1.8 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 EER24536.1 - 0.0074 16.6 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPR_12 PF13424.1 EER24537.1 - 0.00012 21.9 2.1 0.0034 17.2 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4164 PF13747.1 EER24537.1 - 0.015 15.4 3.1 0.015 15.4 2.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TPR_16 PF13432.1 EER24537.1 - 0.027 15.1 0.5 0.027 15.1 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EER24537.1 - 0.034 14.0 0.7 0.034 14.0 0.5 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat LRS4 PF10422.4 EER24537.1 - 0.052 12.9 0.4 0.076 12.3 0.3 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF92 PF01940.11 EER24538.1 - 4.7e-55 186.1 7.8 1.8e-46 158.1 0.9 2.1 2 0 0 2 2 2 2 Integral membrane protein DUF92 Radical_SAM PF04055.16 EER24539.1 - 2.5e-10 40.7 0.0 3.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EER24539.1 - 2.4e-06 27.7 0.0 4.4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EER24539.1 - 0.00043 20.2 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain RNA_pol PF00940.14 EER24540.1 - 5.7e-168 558.5 0.0 9.4e-168 557.8 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EER24540.1 - 6.8e-77 258.8 0.0 1.2e-76 258.0 0.0 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Viral_DNA_bp PF00747.12 EER24540.1 - 0.21 8.7 0.0 0.32 8.1 0.0 1.1 1 0 0 1 1 1 0 ssDNA binding protein Sin_N PF04801.8 EER24541.1 - 2.4e-29 102.4 1.3 3.1e-28 98.7 0.9 1.9 1 1 0 1 1 1 1 Sin-like protein conserved region NIR_SIR PF01077.17 EER24542.1 - 2.1e-50 170.1 0.0 1.5e-43 147.8 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EER24542.1 - 1.3e-31 108.0 0.0 2.4e-14 52.6 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EER24542.1 - 2.7e-29 102.0 0.0 5.2e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EER24542.1 - 1.2e-07 31.4 0.1 2.9e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 EER24543.1 - 1.1e-57 194.8 0.1 1.3e-57 194.5 0.1 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Ras PF00071.17 EER24544.1 - 3.3e-49 166.3 0.2 4e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER24544.1 - 1.1e-11 45.3 0.0 1.6e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER24544.1 - 4.5e-11 42.2 0.2 5.5e-11 42.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EER24544.1 - 1.5e-06 27.7 0.0 2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EER24544.1 - 0.023 13.8 0.1 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ATP-synt_C PF00137.16 EER24545.1 - 2.5e-28 97.7 28.5 2.6e-18 65.6 4.9 2.4 3 0 0 3 3 3 2 ATP synthase subunit C Lysis_S PF04971.7 EER24545.1 - 0.17 11.5 0.1 0.17 11.5 0.0 2.4 3 0 0 3 3 3 0 Lysis protein S Oxidored_q2 PF00420.19 EER24545.1 - 0.38 10.3 3.8 1.3 8.7 1.9 2.3 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.19 EER24546.1 - 3.6e-47 159.4 0.1 5e-25 87.5 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EER24546.1 - 2.6e-33 114.6 0.5 4.1e-33 114.0 0.3 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EER24546.1 - 1.2e-15 57.2 0.0 2.6e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) DDHD PF02862.12 EER24547.1 - 6.2e-33 114.4 0.9 9.4e-32 110.6 0.0 2.9 2 2 0 2 2 2 1 DDHD domain DUF2305 PF10230.4 EER24547.1 - 0.0067 15.8 0.1 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_5 PF12695.2 EER24547.1 - 0.028 14.1 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 EER24549.1 - 7.6e-74 248.8 0.0 9.4e-74 248.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EER24549.1 - 2.6e-36 124.7 0.0 3.8e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EER24549.1 - 0.001 18.0 0.0 0.026 13.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EER24549.1 - 0.0083 16.5 0.0 0.046 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EER24549.1 - 0.012 14.5 0.0 0.095 11.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EER24549.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 EER24549.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EER24549.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER24549.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DUF1313 PF07011.6 EER24549.1 - 0.19 11.3 0.0 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) DUF866 PF05907.8 EER24550.1 - 1.5e-25 89.5 0.0 1.6e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 EER24552.1 - 2.8e-18 65.2 0.1 3.5e-18 64.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain DASH_Dad1 PF08649.5 EER24553.1 - 1.2e-24 85.6 3.5 1.6e-24 85.3 2.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 WVELL PF14043.1 EER24553.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 WVELL protein DASH_Dad4 PF08650.5 EER24553.1 - 0.091 12.6 0.3 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad4 ATP-synt_E_2 PF08112.6 EER24553.1 - 0.14 12.2 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 ATP synthase epsilon subunit Ras PF00071.17 EER24554.1 - 6.7e-48 162.1 0.0 8.5e-48 161.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER24554.1 - 3.5e-12 46.8 0.0 5.1e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER24554.1 - 7.2e-05 22.0 0.0 0.00015 21.0 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EER24554.1 - 0.037 13.2 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EER24554.1 - 0.095 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PAP2 PF01569.16 EER24555.1 - 2.7e-16 59.4 3.6 7.8e-16 57.9 2.5 1.7 1 0 0 1 1 1 1 PAP2 superfamily Peptidase_C48 PF02902.14 EER24556.1 - 2.8e-24 85.9 0.0 5.7e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_S30 PF01577.11 EER24556.1 - 0.31 10.4 1.6 0.58 9.4 1.1 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease Pro-rich PF15240.1 EER24557.1 - 0.56 10.2 7.3 1.2 9.1 0.5 2.6 3 1 0 3 3 3 0 Proline-rich Reo_sigmaC PF04582.7 EER24558.1 - 2.7e-05 23.5 8.3 0.00018 20.7 4.9 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein DUF1664 PF07889.7 EER24558.1 - 5.8e-05 22.8 6.2 0.29 10.9 0.2 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF1664) ADIP PF11559.3 EER24558.1 - 0.00078 19.3 3.6 0.0046 16.8 0.8 2.4 1 1 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF677 PF05055.7 EER24558.1 - 0.0041 15.8 1.2 0.0078 14.9 0.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF677) Atg14 PF10186.4 EER24558.1 - 0.061 12.2 3.6 0.14 11.0 2.5 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 EER24558.1 - 0.064 13.1 0.7 3.9 7.4 0.0 2.8 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 EER24558.1 - 0.075 13.3 2.4 4.6 7.6 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) COG5 PF10392.4 EER24558.1 - 0.098 12.6 6.6 1.5 8.8 2.1 2.6 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Lge1 PF11488.3 EER24558.1 - 0.12 12.6 3.9 1.4 9.1 0.3 2.7 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 EER24558.1 - 0.14 11.6 3.4 0.23 11.0 2.3 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EER24558.1 - 0.15 11.0 0.8 0.23 10.4 0.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 NPV_P10 PF05531.7 EER24558.1 - 0.5 10.6 5.7 37 4.6 2.3 3.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Cpl-7 PF08230.6 EER24558.1 - 0.57 9.9 3.0 11 5.8 0.0 3.2 4 0 0 4 4 4 0 Cpl-7 lysozyme C-terminal domain Fib_alpha PF08702.5 EER24558.1 - 0.73 9.9 6.4 0.44 10.6 0.8 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family LPP PF04728.8 EER24558.1 - 2.6 7.9 5.6 5.2 6.9 0.7 3.3 2 1 2 4 4 4 0 Lipoprotein leucine-zipper DENN PF02141.16 EER24559.1 - 3.4e-38 131.2 0.0 6.1e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EER24559.1 - 0.00034 20.5 0.0 0.00098 19.0 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EER24559.1 - 0.015 15.6 6.0 0.015 15.6 4.2 2.6 2 1 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A GDE_N PF12439.3 EER24559.1 - 0.49 9.5 4.5 2.7 7.1 0.7 2.9 2 1 1 3 3 3 0 Glycogen debranching enzyme N terminal DUF3450 PF11932.3 EER24559.1 - 1.5 8.0 19.3 3 7.0 3.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) zf-HIT PF04438.11 EER24560.1 - 6.9e-10 38.3 10.5 1.2e-09 37.6 7.3 1.4 1 0 0 1 1 1 1 HIT zinc finger adh_short PF00106.20 EER24561.1 - 1.3e-28 100.0 0.3 1.9e-28 99.4 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER24561.1 - 3.1e-25 89.3 0.1 3.7e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER24561.1 - 5.3e-12 45.7 0.4 1.2e-11 44.6 0.2 1.5 1 1 0 1 1 1 1 KR domain PA PF02225.17 EER24561.1 - 0.058 13.0 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 PA domain RabGAP-TBC PF00566.13 EER24562.1 - 4.7e-44 150.4 0.0 1.8e-42 145.2 0.0 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Choline_kin_N PF04428.9 EER24563.1 - 0.046 13.1 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Choline kinase N terminus Pkinase PF00069.20 EER24564.1 - 2.9e-26 92.1 0.0 5.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EER24564.1 - 1.1e-16 59.9 3.0 2.4e-09 36.7 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.17 EER24564.1 - 7.6e-12 44.2 7.7 0.014 15.4 0.2 6.9 6 0 0 6 6 6 3 HEAT repeat Pkinase_Tyr PF07714.12 EER24564.1 - 4e-08 32.6 0.0 6.5e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EER24564.1 - 1.3e-06 28.5 3.9 0.016 15.4 0.0 4.1 2 1 2 4 4 4 3 HEAT repeats DUF2454 PF10521.4 EER24564.1 - 0.01 14.8 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) Kinase-like PF14531.1 EER24564.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HEAT_EZ PF13513.1 EER24564.1 - 2.4 8.7 8.0 1.1 9.8 0.3 3.9 5 0 0 5 5 5 0 HEAT-like repeat zf-C2H2_4 PF13894.1 EER24565.1 - 5.1e-11 42.0 18.3 0.00077 19.6 0.8 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EER24565.1 - 2.7e-10 39.9 24.9 0.00052 20.2 2.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER24565.1 - 0.0018 18.4 25.0 0.21 11.9 0.3 4.0 4 0 0 4 4 3 3 Zinc-finger double domain zf-C2H2_3 PF13878.1 EER24565.1 - 0.02 14.4 3.1 0.1 12.2 1.0 2.6 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO CpXC PF14353.1 EER24565.1 - 0.028 14.3 3.6 0.27 11.2 0.3 2.4 1 1 1 2 2 2 0 CpXC protein zinc_ribbon_2 PF13240.1 EER24565.1 - 0.15 11.6 4.2 5 6.7 0.5 2.9 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EER24565.1 - 0.2 11.3 6.3 2.1 8.1 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain UPF0547 PF10571.4 EER24565.1 - 0.25 11.0 4.4 1.6 8.5 0.4 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_5 PF13719.1 EER24565.1 - 0.34 10.5 6.3 2.2 7.9 0.3 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.2 EER24565.1 - 0.36 10.9 11.2 4.1 7.5 1.7 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SIR2 PF02146.12 EER24565.1 - 8.5 6.0 7.4 15 5.2 4.4 1.8 1 1 1 2 2 2 0 Sir2 family OrfB_Zn_ribbon PF07282.6 EER24565.1 - 8.7 6.0 13.5 1.3 8.6 1.3 2.6 1 1 0 2 2 2 0 Putative transposase DNA-binding domain NUDIX PF00293.23 EER24566.1 - 7.5e-29 100.0 0.0 1.3e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain MatE PF01554.13 EER24567.1 - 1.2e-52 177.8 27.2 2.3e-30 105.3 7.2 2.2 2 0 0 2 2 2 2 MatE DnaJ PF00226.26 EER24568.1 - 7.9e-14 51.1 1.0 4.5e-13 48.7 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain IBB PF01749.15 EER24568.1 - 5 7.3 19.5 5.6 7.2 12.0 2.2 1 1 1 2 2 2 0 Importin beta binding domain DEAD PF00270.24 EER24569.1 - 7.9e-45 152.3 0.1 1.5e-44 151.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EER24569.1 - 1.3e-25 88.6 0.1 3.4e-25 87.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EER24569.1 - 1.1e-21 76.4 0.2 3.4e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER24569.1 - 0.0034 17.2 0.0 0.0034 17.2 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EER24569.1 - 0.005 15.6 0.0 0.01 14.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EER24569.1 - 0.016 15.1 0.0 0.069 13.0 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain AA_permease PF00324.16 EER24570.1 - 2.9e-122 408.4 38.2 3.3e-122 408.2 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER24570.1 - 1.3e-39 135.9 44.3 1.6e-39 135.6 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.13 EER24571.1 - 0.00018 21.3 10.6 0.00036 20.3 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EER24572.1 - 5.2e-44 149.7 0.0 1.5e-43 148.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER24572.1 - 7.7e-21 73.7 0.1 4e-20 71.4 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EER24572.1 - 1.2e-20 73.0 2.4 1.2e-20 73.0 1.7 2.7 2 0 0 2 2 2 1 DBP10CT (NUC160) domain RPA_C PF08784.6 EER24573.1 - 6.1e-15 55.4 0.2 2e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EER24573.1 - 3e-06 26.9 0.1 8.8e-06 25.5 0.1 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain PAPS_reduct PF01507.14 EER24574.1 - 4.2e-28 98.3 0.0 3.7e-26 91.9 0.0 2.4 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 EER24575.1 - 2.5e-20 71.8 0.3 1.2e-10 40.8 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER24575.1 - 3e-14 52.7 0.1 1e-05 25.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER24575.1 - 0.0035 17.1 3.1 0.11 12.3 0.2 3.0 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EER24576.1 - 1.9e-61 207.2 0.0 2.8e-61 206.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EER24576.1 - 6.4e-33 113.7 2.3 1.8e-32 112.3 1.6 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EER24576.1 - 2e-23 83.0 0.0 1e-22 80.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain MOR2-PAG1_N PF14222.1 EER24577.1 - 4.2e-230 765.1 0.0 7.5e-230 764.3 0.0 1.4 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EER24577.1 - 5.7e-97 324.5 0.3 2.2e-96 322.6 0.2 2.1 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EER24577.1 - 1.8e-37 128.5 11.8 3.5e-17 61.3 0.0 4.0 2 1 1 3 3 3 3 Cell morphogenesis central region Cu_amine_oxid PF01179.15 EER24578.1 - 1.4e-170 567.4 0.2 1.7e-170 567.2 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EER24578.1 - 7.8e-07 29.0 0.1 1.5e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EER24578.1 - 0.00063 19.7 0.1 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain PhoD PF09423.5 EER24579.1 - 5.2e-151 503.2 0.0 6e-151 503.0 0.0 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase HhH-GPD PF00730.20 EER24581.1 - 2.8e-15 56.5 0.0 1e-14 54.7 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EER24581.1 - 7e-08 31.7 0.0 3e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif UQ_con PF00179.21 EER24582.1 - 6.7e-40 135.7 0.0 7.8e-40 135.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER24582.1 - 0.00017 21.3 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EER24582.1 - 0.044 13.6 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.6 EER24582.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 PAS_9 PF13426.1 EER24584.1 - 5.7e-26 90.9 0.0 3e-18 66.0 0.0 2.6 2 0 0 2 2 2 2 PAS domain HATPase_c PF02518.21 EER24584.1 - 2.1e-25 88.5 0.0 4.1e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EER24584.1 - 8.9e-23 80.4 0.3 2.2e-22 79.1 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EER24584.1 - 4.9e-19 68.0 0.2 1.1e-18 66.9 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EER24584.1 - 2e-17 63.2 0.0 1.3e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.19 EER24584.1 - 1.4e-15 57.0 0.0 1.3e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EER24584.1 - 3.2e-05 23.5 0.0 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 PAS domain PAS_10 PF13596.1 EER24584.1 - 4.2e-05 23.7 0.0 0.0011 19.1 0.0 2.5 2 0 0 2 2 2 1 PAS domain Gemin7 PF11095.3 EER24584.1 - 0.00042 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) PAS_3 PF08447.6 EER24584.1 - 0.0069 16.4 0.1 0.015 15.4 0.1 1.6 1 0 0 1 1 1 1 PAS fold AAA_11 PF13086.1 EER24585.1 - 3.9e-63 213.1 0.3 7.4e-63 212.2 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EER24585.1 - 1.3e-56 191.1 0.0 2.3e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER24585.1 - 1.6e-13 50.1 2.8 1.6e-12 46.9 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain AAA_30 PF13604.1 EER24585.1 - 4.8e-11 42.6 0.3 3.7e-07 29.9 0.0 3.3 2 1 2 4 4 4 2 AAA domain Viral_helicase1 PF01443.13 EER24585.1 - 1.2e-07 31.4 0.0 0.19 11.2 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EER24585.1 - 1.6e-07 31.3 0.0 3.1e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EER24585.1 - 3.3e-06 26.6 0.1 0.00079 18.8 0.0 2.1 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EER24585.1 - 5.3e-06 25.6 0.7 3.1e-05 23.1 0.5 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EER24585.1 - 2.3e-05 24.5 0.1 0.00062 19.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EER24585.1 - 0.0004 19.9 0.5 0.11 11.9 0.0 3.0 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EER24585.1 - 0.00064 19.0 0.0 0.072 12.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.1 EER24585.1 - 0.001 19.0 1.8 0.0017 18.3 0.5 2.0 2 1 0 2 2 2 1 AAA ATPase domain Zot PF05707.7 EER24585.1 - 0.0011 18.5 0.0 0.0034 16.8 0.0 1.8 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) T2SE PF00437.15 EER24585.1 - 0.0016 17.4 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 EER24585.1 - 0.0048 16.3 0.1 0.086 12.2 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EER24585.1 - 0.0056 16.4 0.1 0.075 12.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Flavi_DEAD PF07652.9 EER24585.1 - 0.0057 16.4 0.0 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Flavivirus DEAD domain AAA PF00004.24 EER24585.1 - 0.008 16.3 0.2 0.039 14.1 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 4HB_MCP_1 PF12729.2 EER24585.1 - 0.018 14.3 0.2 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction AAA_10 PF12846.2 EER24585.1 - 0.019 14.4 0.0 0.095 12.1 0.0 2.0 1 1 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EER24585.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EER24585.1 - 0.028 13.8 0.0 0.069 12.6 0.0 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EER24585.1 - 0.066 13.5 0.0 2.4 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EER24585.1 - 0.11 11.1 0.0 0.22 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 EER24585.1 - 0.17 12.7 1.0 0.62 10.8 0.6 2.1 1 1 0 1 1 1 0 AAA domain PIG-F PF06699.6 EER24588.1 - 6e-55 186.1 1.9 7.9e-55 185.7 1.3 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F ABC2_membrane PF01061.19 EER24588.1 - 0.052 12.7 2.8 0.86 8.7 1.3 2.3 2 1 0 2 2 2 0 ABC-2 type transporter Gly-zipper_Omp PF13488.1 EER24588.1 - 0.98 9.1 12.7 0.36 10.4 1.0 2.7 3 0 0 3 3 3 0 Glycine zipper Rick_17kDa_Anti PF05433.10 EER24588.1 - 1.6 8.4 12.0 1.6 8.4 1.0 3.2 3 0 0 3 3 3 0 Glycine zipper 2TM domain ADH_N PF08240.7 EER24590.1 - 4.9e-28 97.0 2.2 1.4e-27 95.5 1.5 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER24590.1 - 6.4e-17 61.3 0.2 1.3e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EER24590.1 - 0.069 12.5 0.2 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EER24590.1 - 0.086 12.6 1.2 1.6 8.5 0.7 2.3 1 1 1 2 2 2 0 ThiF family Pyr_redox_3 PF13738.1 EER24590.1 - 0.095 12.7 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-Tim10_DDP PF02953.10 EER24591.1 - 2.6e-18 65.0 5.4 3.4e-18 64.6 3.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EER24591.1 - 0.017 14.5 3.6 0.042 13.2 2.3 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) QueF PF14489.1 EER24591.1 - 0.11 12.5 0.4 3.2 7.7 0.0 2.2 1 1 1 2 2 2 0 QueF-like protein UPF0203 PF05254.7 EER24591.1 - 0.15 11.9 2.7 3.2 7.6 0.4 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0203) Vicilin_N PF04702.7 EER24591.1 - 0.21 11.1 3.7 0.27 10.8 2.6 1.1 1 0 0 1 1 1 0 Vicilin N terminal region RhoGAP PF00620.22 EER24592.1 - 6.5e-38 129.7 0.0 1.3e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain DUF2284 PF10050.4 EER24593.1 - 0.0029 17.2 85.3 1.8 8.1 1.1 9.8 9 1 1 10 10 10 9 Predicted metal-binding protein (DUF2284) PS_Dcarbxylase PF02666.10 EER24594.1 - 3.9e-29 101.4 0.0 4.7e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EER24594.1 - 3.4e-10 39.6 0.0 5.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Peptidase_S10 PF00450.17 EER24595.1 - 5.7e-82 276.0 7.8 9.6e-82 275.3 5.4 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase GDPD PF03009.12 EER24596.1 - 5.3e-29 101.4 0.0 7.4e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EER24596.1 - 0.0023 18.0 0.3 0.006 16.7 0.2 1.8 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family LIM PF00412.17 EER24597.1 - 1.5e-16 60.1 19.9 3.1e-11 43.1 2.2 3.2 3 0 0 3 3 3 2 LIM domain zinc_ribbon_4 PF13717.1 EER24597.1 - 5.4 6.7 9.3 4.1 7.1 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EER24597.1 - 6.1 6.5 9.4 3.1 7.4 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain NAD_binding_5 PF07994.7 EER24598.1 - 1.2e-113 379.5 0.1 1.7e-113 379.0 0.0 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EER24598.1 - 1e-44 150.9 0.3 2e-44 149.9 0.2 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase APH PF01636.18 EER24599.1 - 1.3e-08 34.8 0.0 8e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Amidase PF01425.16 EER24600.1 - 3.5e-78 263.4 2.5 6.9e-75 252.5 1.5 2.1 2 0 0 2 2 2 2 Amidase Glyco_hydro_72 PF03198.9 EER24601.1 - 5.8e-132 439.4 1.1 6.9e-132 439.1 0.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EER24601.1 - 3.3e-07 29.8 0.6 2.4e-06 26.9 0.4 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_17 PF00332.13 EER24601.1 - 0.0046 16.0 0.0 0.0069 15.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 FCH PF00611.18 EER24602.1 - 3.8e-23 81.4 0.9 3.8e-22 78.2 0.0 2.9 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 EER24602.1 - 6.2e-15 54.6 4.5 1.1e-14 53.8 3.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Zot PF05707.7 EER24602.1 - 0.015 14.7 0.2 3.4 7.0 0.1 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SH3_1 PF00018.23 EER24602.1 - 0.022 14.1 0.0 0.05 13.0 0.0 1.6 1 0 0 1 1 1 0 SH3 domain C1_2 PF03107.11 EER24602.1 - 0.43 10.7 7.8 0.78 9.9 5.4 1.4 1 0 0 1 1 1 0 C1 domain DEAD PF00270.24 EER24603.1 - 1.5e-34 118.9 0.5 8.1e-34 116.5 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER24603.1 - 1.3e-21 76.2 0.4 2.5e-21 75.2 0.3 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EER24603.1 - 0.01 14.8 0.0 0.028 13.4 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 EER24603.1 - 0.039 13.5 0.1 0.14 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EER24603.1 - 0.079 13.1 0.1 0.35 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain DUF3217 PF11506.3 EER24603.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) Arginase PF00491.16 EER24604.1 - 4e-81 272.3 0.5 4.9e-81 272.0 0.4 1.0 1 0 0 1 1 1 1 Arginase family GAF_2 PF13185.1 EER24605.1 - 6.1e-08 33.2 0.0 1.8e-07 31.7 0.0 1.7 2 0 0 2 2 2 1 GAF domain GAF PF01590.21 EER24605.1 - 6.7e-06 26.3 0.0 9.3e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EER24605.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.4 1 1 0 1 1 1 1 GAF domain Pkinase PF00069.20 EER24606.1 - 1.4e-09 37.4 0.0 2.6e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24606.1 - 9.1e-09 34.7 0.0 6.4e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EER24606.1 - 3.3e-08 33.5 0.4 4.2e-05 23.4 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER24606.1 - 0.0042 16.6 0.1 2.1 7.8 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase Kdo PF06293.9 EER24606.1 - 0.03 13.3 0.0 0.05 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NAD_kinase PF01513.16 EER24608.1 - 5.8e-68 228.7 0.0 7.6e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Pro-kuma_activ PF09286.6 EER24609.1 - 7.5e-28 97.3 0.1 4.2e-27 94.9 0.0 2.2 2 1 1 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EER24609.1 - 8.4e-11 41.5 0.3 1.8e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 Subtilase family ERM PF00769.14 EER24610.1 - 0.00033 20.2 37.2 0.00033 20.2 25.8 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Choline_kinase PF01633.15 EER24610.1 - 0.0093 15.5 0.0 0.0093 15.5 0.0 2.4 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EER24610.1 - 0.03 14.0 0.2 0.13 12.0 0.1 2.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Otopetrin PF03189.8 EER24610.1 - 0.29 10.1 0.2 0.47 9.3 0.1 1.3 1 0 0 1 1 1 0 Otopetrin RRN3 PF05327.6 EER24610.1 - 0.63 8.0 9.1 1.2 7.1 6.3 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DDRGK PF09756.4 EER24610.1 - 1.5 8.2 38.8 4.4 6.6 26.9 1.8 1 0 0 1 1 1 0 DDRGK domain LMBR1 PF04791.11 EER24610.1 - 2.1 6.8 4.7 3.1 6.2 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pilt PF15453.1 EER24610.1 - 2.3 7.8 23.6 0.31 10.6 13.1 1.9 2 0 0 2 2 2 0 Protein incorporated later into Tight Junctions SAPS PF04499.10 EER24610.1 - 4.9 5.6 19.4 0.11 11.0 8.9 1.5 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein E1-E2_ATPase PF00122.15 EER24612.1 - 4.4e-64 215.6 5.7 4.4e-64 215.6 3.9 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EER24612.1 - 6.6e-29 100.7 5.0 6.6e-29 100.7 3.5 2.6 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EER24612.1 - 4.1e-26 92.7 0.1 1e-24 88.1 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EER24612.1 - 5.4e-17 61.0 1.1 1.2e-16 59.8 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EER24612.1 - 2e-14 53.2 0.0 3.8e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EER24612.1 - 1.7e-12 47.8 0.0 5.6e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER24612.1 - 2.6e-06 27.2 2.1 2.1e-05 24.2 1.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2014 PF09427.5 EER24613.1 - 2.5e-104 348.0 0.7 3.5e-104 347.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EER24613.1 - 1.4e-17 63.1 0.6 6.6e-17 60.9 0.5 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Leu_zip PF15294.1 EER24613.1 - 0.049 12.7 4.4 0.084 11.9 3.1 1.2 1 0 0 1 1 1 0 Leucine zipper bZIP_2 PF07716.10 EER24613.1 - 0.065 13.0 8.5 0.033 14.0 2.8 2.3 2 0 0 2 2 2 0 Basic region leucine zipper HAP1_N PF04849.8 EER24613.1 - 0.17 10.8 4.8 0.3 9.9 3.3 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_1 PF00170.16 EER24613.1 - 0.49 10.3 7.8 0.12 12.3 2.9 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 EER24613.1 - 3 8.1 9.0 0.31 11.3 2.6 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DIT1_PvcA PF05141.7 EER24614.1 - 3.7e-86 288.9 0.0 4.6e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 EER24614.1 - 1.1e-25 90.7 0.1 4.2e-25 88.9 0.0 2.0 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family FAD_binding_3 PF01494.14 EER24615.1 - 1.8e-53 181.8 0.0 2.6e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EER24615.1 - 0.00021 20.5 1.5 0.00024 20.2 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EER24615.1 - 0.00029 19.8 0.2 0.0014 17.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EER24615.1 - 0.0052 15.3 1.4 0.0075 14.7 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EER24615.1 - 0.0091 16.0 0.6 0.029 14.3 0.4 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EER24615.1 - 0.01 16.1 0.2 0.078 13.3 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EER24615.1 - 0.021 13.7 0.3 0.2 10.5 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EER24615.1 - 0.081 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EER24615.1 - 0.096 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER24615.1 - 0.1 11.6 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EER24615.1 - 0.12 11.2 1.2 0.2 10.4 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 EER24616.1 - 2.1e-14 53.7 0.0 2.4e-13 50.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER24616.1 - 3.8e-11 43.2 0.0 9.4e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER24616.1 - 1.3e-07 31.4 0.0 2.7e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EER24616.1 - 0.0058 16.6 0.0 0.0079 16.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EER24616.1 - 0.035 14.2 0.0 0.069 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 EER24616.1 - 0.065 11.9 0.0 0.097 11.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CoA_transf_3 PF02515.12 EER24617.1 - 1.8e-26 92.5 0.0 2.2e-25 89.0 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III p450 PF00067.17 EER24619.1 - 1.7e-67 227.9 0.0 2.1e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 P-II PF00543.17 EER24619.1 - 0.15 12.5 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II MFS_1 PF07690.11 EER24620.1 - 4.6e-23 81.4 51.4 6.9e-22 77.6 27.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.17 EER24621.1 - 2.7e-43 147.6 0.0 3.4e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family B12-binding PF02310.14 EER24621.1 - 0.11 12.4 0.0 4.5 7.1 0.0 2.3 2 0 0 2 2 2 0 B12 binding domain Peptidase_U4 PF03419.8 EER24622.1 - 0.031 13.3 0.8 0.049 12.7 0.6 1.3 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Rrn6 PF10214.4 EER24623.1 - 3 5.8 6.8 4 5.4 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor F-box PF00646.28 EER24624.1 - 0.025 14.2 0.7 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EER24624.1 - 0.84 9.4 0.0 0.84 9.4 0.0 2.9 4 0 0 4 4 4 0 F-box-like Transferase PF02458.10 EER24625.1 - 0.15 10.4 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Transferase family Mito_carr PF00153.22 EER24626.1 - 3.6e-54 180.4 0.1 1.9e-18 65.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Anp1 PF03452.9 EER24627.1 - 2.6e-109 364.5 0.0 5.2e-109 363.5 0.0 1.4 1 1 1 2 2 2 1 Anp1 Glycos_transf_2 PF00535.21 EER24627.1 - 0.024 14.3 0.0 0.055 13.1 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Zip PF02535.17 EER24628.1 - 1.8e-60 204.6 2.2 6e-60 202.8 1.5 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.8 EER24628.1 - 6 6.8 16.6 0.58 10.1 1.0 3.5 3 2 1 4 4 4 0 Protein of unknown function (DUF456) Nop16 PF09420.5 EER24629.1 - 1.4e-61 207.3 5.2 1.6e-61 207.1 3.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF2207 PF09972.4 EER24630.1 - 0.1 11.1 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Pex24p PF06398.6 EER24631.1 - 2.7e-92 309.3 0.0 3.2e-92 309.0 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EER24631.1 - 0.047 11.8 0.9 0.095 10.8 0.6 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) DUF3292 PF11696.3 EER24631.1 - 0.12 10.2 3.7 0.11 10.4 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3292) PRT_C PF08372.5 EER24631.1 - 0.14 11.6 1.0 0.29 10.6 0.2 1.9 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal Pkinase PF00069.20 EER24632.1 - 5.3e-59 199.4 0.0 8.7e-59 198.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24632.1 - 7.3e-21 74.3 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER24632.1 - 0.014 15.0 0.0 0.12 12.0 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family COPIIcoated_ERV PF07970.7 EER24633.1 - 4.6e-34 117.9 0.1 1.2e-32 113.3 0.1 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EER24633.1 - 2.8e-21 75.2 0.0 5.2e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ADH_N PF08240.7 EER24634.1 - 1.7e-21 75.9 2.4 3.2e-21 75.1 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER24634.1 - 1.6e-12 47.0 0.0 3.7e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EER24634.1 - 0.0087 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EER24634.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA CoA_binding PF02629.14 EER24634.1 - 0.13 12.7 0.1 0.92 10.0 0.0 2.1 2 0 0 2 2 2 0 CoA binding domain CENP-Q PF13094.1 EER24635.1 - 5.3 7.0 59.6 0.31 11.0 18.4 4.8 2 1 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Maf1 PF09174.5 EER24636.1 - 1.7e-64 216.9 0.0 2.3e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Type_III_YscX PF09474.5 EER24636.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system YscX (type_III_YscX) Clat_adaptor_s PF01217.15 EER24637.1 - 1.1e-51 174.2 1.8 1.3e-51 174.0 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.3 EER24637.1 - 0.087 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 EER24638.1 - 4.6e-12 45.3 0.0 6.5e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.9 EER24639.1 - 8.9e-10 37.9 0.0 7.5e-07 28.4 0.0 2.9 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EER24639.1 - 5.5e-07 28.9 0.0 7.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EER24639.1 - 5e-06 26.4 0.3 0.014 15.1 0.0 2.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EER24639.1 - 0.0012 18.2 0.0 0.29 10.4 0.0 2.8 3 0 0 3 3 3 2 RIO1 family Choline_kinase PF01633.15 EER24639.1 - 0.003 17.1 0.0 0.0039 16.7 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EER24639.1 - 0.038 13.0 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase STE2 PF02116.10 EER24640.1 - 1.1e-87 293.7 16.8 1.2e-87 293.5 11.7 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR UEV PF05743.8 EER24641.1 - 2.4e-37 127.3 0.1 3.8e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EER24641.1 - 9.8e-21 73.1 0.2 3.6e-20 71.3 0.0 2.1 3 0 0 3 3 3 1 Vps23 core domain UQ_con PF00179.21 EER24641.1 - 0.0064 15.9 0.1 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Reo_sigmaC PF04582.7 EER24641.1 - 0.038 13.1 4.7 0.057 12.6 3.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 EER24641.1 - 0.06 13.2 2.4 0.096 12.5 1.7 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cep57_MT_bd PF06657.8 EER24641.1 - 0.11 12.4 0.1 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Bacillus_HBL PF05791.6 EER24641.1 - 0.23 10.8 1.2 0.35 10.2 0.8 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Tht1 PF04163.7 EER24641.1 - 0.31 9.3 0.4 0.44 8.8 0.3 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein IDO PF01231.13 EER24642.1 - 4e-160 532.8 0.0 4.6e-160 532.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Aminotran_5 PF00266.14 EER24643.1 - 6.4e-96 321.3 0.0 8e-96 320.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EER24643.1 - 2.6e-08 33.3 0.0 3.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EER24643.1 - 1.1e-05 24.7 0.0 2.5e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EER24643.1 - 0.0032 15.9 0.0 0.0046 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain GST_N_3 PF13417.1 EER24644.1 - 4.1e-17 62.1 0.0 7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EER24644.1 - 6.9e-16 58.1 0.0 1.1e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EER24644.1 - 3.3e-12 46.2 0.0 4.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EER24644.1 - 5.3e-12 45.5 0.0 8.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER24644.1 - 3.7e-05 23.5 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EER24644.1 - 0.003 17.9 0.0 0.0037 17.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain APH PF01636.18 EER24645.1 - 0.0023 17.7 0.2 0.0059 16.3 0.1 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Sugar_tr PF00083.19 EER24646.1 - 1.5e-79 267.6 21.7 1.8e-79 267.4 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER24646.1 - 1.2e-12 47.2 31.6 1.8e-10 40.0 7.1 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily BAR PF03114.13 EER24647.1 - 8.1e-63 211.9 5.1 1e-62 211.6 3.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EER24647.1 - 2.4e-13 49.2 0.1 4.7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EER24647.1 - 1.1e-08 34.4 0.0 2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EER24647.1 - 1.3e-07 31.0 0.0 3.8e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EER24647.1 - 0.0045 16.2 6.3 0.8 8.9 2.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like APG6 PF04111.7 EER24647.1 - 1.8 7.5 7.4 11 4.9 0.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 TMPIT PF07851.8 EER24647.1 - 3.1 6.7 6.2 0.83 8.6 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein OmpH PF03938.9 EER24647.1 - 8.3 6.3 9.3 27 4.6 6.4 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) COesterase PF00135.23 EER24648.1 - 5.1e-90 302.7 0.0 7e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EER24648.1 - 0.0008 19.0 0.0 0.0023 17.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Det1 PF09737.4 EER24648.1 - 0.01 14.6 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Peptidase_S9 PF00326.16 EER24648.1 - 0.03 13.5 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Kdo PF06293.9 EER24649.1 - 0.00012 21.1 0.3 0.00026 20.1 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER24649.1 - 0.00039 20.2 1.9 0.012 15.3 0.3 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EER24649.1 - 0.056 12.7 0.0 0.46 9.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pex16 PF08610.5 EER24649.1 - 0.94 8.4 3.6 1.6 7.6 2.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) AlaDh_PNT_N PF05222.10 EER24650.1 - 1.4e-24 86.5 0.0 2.2e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EER24650.1 - 7.8e-05 22.2 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F-box PF00646.28 EER24651.1 - 4.7e-06 26.1 0.0 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER24651.1 - 0.00079 19.0 0.0 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like tRNA-synt_1c PF00749.16 EER24652.1 - 6.7e-97 323.9 0.0 8.5e-97 323.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EER24652.1 - 1.8e-32 112.4 0.0 5.3e-31 107.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain Hydrolase PF00702.21 EER24653.1 - 1.6e-21 77.7 0.0 8.7e-21 75.3 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EER24653.1 - 1.2e-19 70.3 0.0 9.3e-19 67.3 0.0 2.2 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EER24653.1 - 1.7e-19 70.7 0.0 5.4e-19 69.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER24653.1 - 0.0014 18.5 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EER24653.1 - 0.0015 18.1 0.1 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EER24653.1 - 0.038 13.3 0.4 1.1 8.4 0.0 2.8 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase FYVE PF01363.16 EER24654.1 - 1.3e-22 79.4 26.8 3.9e-17 61.8 3.4 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 EER24654.1 - 0.00021 21.3 11.5 0.018 15.1 0.0 3.3 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding DUF866 PF05907.8 EER24654.1 - 0.2 11.1 3.0 3.8 6.9 1.2 2.7 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) zf-AN1 PF01428.11 EER24654.1 - 0.41 10.5 26.3 0.048 13.5 5.1 3.4 3 0 0 3 3 3 0 AN1-like Zinc finger PKD_channel PF08016.7 EER24655.1 - 3.9e-07 28.8 15.8 4.1e-06 25.4 10.9 2.1 1 1 0 1 1 1 1 Polycystin cation channel CAML PF14963.1 EER24655.1 - 0.12 11.7 3.6 0.23 10.7 2.5 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand EIF_2_alpha PF07541.7 EER24656.1 - 6.2e-40 135.4 0.0 1.1e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EER24656.1 - 2.9e-13 49.7 0.6 6e-13 48.6 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Sulfate_transp PF00916.15 EER24657.1 - 3.6e-34 118.0 2.2 7.9e-34 116.9 0.3 2.2 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EER24657.1 - 1.6e-26 91.8 2.4 1.6e-26 91.8 1.7 2.2 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EER24657.1 - 7e-17 60.9 0.0 1.3e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EER24657.1 - 0.0024 17.8 0.0 0.0061 16.5 0.0 1.7 1 1 0 1 1 1 1 STAS domain DUF3068 PF11271.3 EER24657.1 - 0.46 9.4 0.7 0.67 8.9 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) CENP-L PF13092.1 EER24658.1 - 2.3e-55 186.8 0.0 3.4e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Acetyltransf_1 PF00583.19 EER24659.1 - 7.3e-08 32.3 0.0 1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER24659.1 - 8.1e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER24659.1 - 0.0024 17.9 0.0 0.0033 17.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER24659.1 - 0.0088 15.8 0.0 0.021 14.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Peptidase_M35 PF02102.10 EER24661.1 - 0.006 15.2 0.0 0.009 14.7 0.0 1.1 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Palm_thioest PF02089.10 EER24662.1 - 3.6e-66 222.9 0.0 4.5e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 EER24662.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 EER24662.1 - 0.017 14.4 0.0 0.026 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_1 PF00561.15 EER24662.1 - 0.061 12.8 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3328 PF11807.3 EER24665.1 - 5.1e-34 117.8 0.4 6.3e-23 81.5 2.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) BAR PF03114.13 EER24666.1 - 0.022 14.2 1.1 0.037 13.5 0.8 1.3 1 0 0 1 1 1 0 BAR domain KTI12 PF08433.5 EER24667.1 - 1e-64 218.3 0.0 3.6e-64 216.5 0.0 1.9 1 1 0 1 1 1 1 Chromatin associated protein KTI12 F-box-like PF12937.2 EER24668.1 - 1.9e-05 24.3 0.9 3.8e-05 23.3 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER24668.1 - 0.0074 15.9 0.9 0.036 13.7 0.1 2.5 2 0 0 2 2 2 1 F-box domain Methyltransf_16 PF10294.4 EER24669.1 - 9.5e-13 47.9 0.0 1.5e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EER24669.1 - 0.0036 17.0 0.0 0.0057 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EER24669.1 - 0.021 13.7 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF3403 PF11883.3 EER24669.1 - 0.13 12.4 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) Antimicrobial_1 PF08018.6 EER24669.1 - 0.17 11.7 1.1 2.1 8.3 0.2 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide Aminotran_1_2 PF00155.16 EER24672.1 - 3e-39 134.9 0.0 4e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EER24672.1 - 0.095 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase GLTP PF08718.6 EER24673.1 - 2.5e-44 150.9 0.0 3.3e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH_4 PF15404.1 EER24674.1 - 1.1e-58 197.8 2.0 5.2e-58 195.6 0.0 3.0 3 1 0 3 3 3 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EER24674.1 - 4.4e-25 86.9 0.8 4.4e-25 86.9 0.5 2.1 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.24 EER24674.1 - 3.9e-08 33.4 0.3 0.017 15.3 0.0 4.0 3 0 0 3 3 3 2 PH domain mRNA_stabil PF13929.1 EER24674.1 - 0.0042 16.0 0.1 0.009 15.0 0.0 1.5 1 0 0 1 1 1 1 mRNA stabilisation PH_9 PF15410.1 EER24674.1 - 0.029 14.5 0.0 2.1 8.5 0.0 3.1 2 0 0 2 2 2 0 Pleckstrin homology domain PH_6 PF15406.1 EER24674.1 - 0.051 13.6 0.1 0.49 10.4 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_S24 PF00717.18 EER24675.1 - 1.1e-05 25.0 0.0 4.3e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EER24675.1 - 0.0013 18.2 0.0 0.0058 16.1 0.0 2.0 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Macro PF01661.16 EER24676.1 - 1.3e-38 131.5 0.0 2e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Macro domain VWA_3 PF13768.1 EER24677.1 - 4.7e-32 110.8 0.0 1e-31 109.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EER24677.1 - 5.2e-25 87.4 0.1 1.4e-24 86.0 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EER24677.1 - 9.1e-14 51.9 0.0 1.7e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EER24677.1 - 8.4e-12 44.3 0.0 2.6e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EER24677.1 - 9.3e-08 31.9 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EER24677.1 - 0.0028 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 EER24677.1 - 0.094 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein GATA PF00320.22 EER24678.1 - 3.9e-15 54.9 4.3 6.6e-15 54.1 3.0 1.4 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EER24678.1 - 0.077 13.0 1.9 0.15 12.0 1.3 1.4 1 0 0 1 1 1 0 zinc-finger DUF1155 PF06633.6 EER24678.1 - 0.21 10.8 1.7 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1155) GCS PF03074.11 EER24679.1 - 1.2e-154 514.8 0.0 1.7e-154 514.3 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase p450 PF00067.17 EER24680.1 - 2.4e-58 197.7 0.0 5.5e-58 196.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EER24681.1 - 1.4e-17 63.9 0.0 2.1e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER24681.1 - 1.3e-10 41.7 0.0 6.8e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER24681.1 - 3.1e-08 33.3 0.0 1.9e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER24681.1 - 6.4e-07 29.7 0.0 3.1e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER24681.1 - 2e-06 28.1 0.0 3.9e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EER24681.1 - 0.00049 20.1 0.0 0.0018 18.3 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.9 EER24681.1 - 0.00097 18.5 0.0 0.042 13.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EER24681.1 - 0.0016 18.4 0.0 0.044 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER24681.1 - 0.0028 18.0 0.0 0.0067 16.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EER24681.1 - 0.045 12.7 0.0 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase NDUF_B7 PF05676.8 EER24683.1 - 1.8e-28 97.7 3.7 2.1e-28 97.5 2.6 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EER24683.1 - 0.0049 16.6 2.1 0.0065 16.2 1.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ank_5 PF13857.1 EER24684.1 - 1.3e-11 44.3 1.0 8.1e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EER24684.1 - 1.6e-11 44.3 0.1 1.1e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EER24684.1 - 3.2e-11 42.4 0.9 1e-08 34.5 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EER24684.1 - 1.1e-10 40.7 0.3 7.5e-05 22.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EER24684.1 - 2.6e-09 37.3 0.2 4.8e-05 23.7 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) KilA-N PF04383.8 EER24684.1 - 1.4e-05 24.6 0.2 0.00019 20.9 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain BORG_CEP PF14957.1 EER24684.1 - 5.9 7.8 7.4 0.88 10.4 0.4 2.8 2 1 0 2 2 2 0 Cdc42 effector DUF1212 PF06738.7 EER24686.1 - 2.8e-54 183.5 9.6 2.6e-49 167.3 0.0 3.1 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EER24686.1 - 3e-33 114.5 6.6 3e-33 114.5 4.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) Metallophos PF00149.23 EER24687.1 - 1.9e-06 27.4 0.2 0.00039 19.8 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER24687.1 - 3.3e-05 23.7 0.0 0.00014 21.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PS_Dcarbxylase PF02666.10 EER24689.1 - 6.4e-51 172.5 0.0 9.5e-51 171.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EER24689.1 - 4.2e-34 116.2 0.1 1.6e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EER24689.1 - 0.00091 19.3 0.1 0.0035 17.4 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EER24689.1 - 0.0067 15.6 0.0 0.025 13.8 0.0 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EER24689.1 - 0.01 15.6 0.0 0.053 13.4 0.0 2.3 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 EER24689.1 - 0.082 12.2 0.0 0.31 10.4 0.0 2.0 1 0 0 1 1 1 0 EF hand APH PF01636.18 EER24690.1 - 5.2e-07 29.6 0.2 1.4e-06 28.1 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER24690.1 - 0.0025 17.4 0.0 0.0068 15.9 0.0 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EER24691.1 - 2e-13 50.1 0.1 3.3e-13 49.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24691.1 - 6.8e-10 38.4 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EER24691.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EER24691.1 - 0.0039 16.2 0.1 0.0075 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EER24691.1 - 0.0045 16.0 0.0 0.0088 15.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like MIS13 PF08202.6 EER24692.1 - 1.8e-50 171.7 1.7 4.6e-50 170.3 1.1 1.6 1 1 0 1 1 1 1 Mis12-Mtw1 protein family DivIC PF04977.10 EER24692.1 - 0.019 14.4 0.4 0.039 13.4 0.2 1.5 1 0 0 1 1 1 0 Septum formation initiator MerR-DNA-bind PF09278.6 EER24692.1 - 4.4 7.7 6.9 0.8 10.1 1.8 2.1 2 0 0 2 2 2 0 MerR, DNA binding Sugar_tr PF00083.19 EER24693.1 - 4.8e-86 289.1 10.5 6.9e-86 288.5 7.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER24693.1 - 5.5e-32 110.8 38.5 1.2e-23 83.4 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EER24694.1 - 6.1e-64 215.6 0.0 8e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24694.1 - 1.7e-30 105.9 0.0 2.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER24694.1 - 0.0039 16.1 0.0 0.0082 15.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like MCM PF00493.18 EER24695.1 - 1.7e-138 461.0 0.1 2.3e-138 460.5 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EER24695.1 - 7.9e-31 107.1 32.6 7.9e-31 107.1 22.6 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EER24695.1 - 2.6e-16 60.2 0.0 8.6e-16 58.5 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EER24695.1 - 4.7e-08 32.4 0.1 8e-06 25.1 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EER24695.1 - 1.1e-06 28.3 0.0 5.1e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EER24695.1 - 0.00037 20.1 0.0 0.0036 16.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EER24695.1 - 0.0079 15.6 0.2 0.13 11.7 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain zf-TFIIB PF13453.1 EER24695.1 - 0.011 14.9 1.1 0.023 13.8 0.8 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF164 PF02591.10 EER24695.1 - 0.016 14.9 0.3 0.043 13.6 0.2 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-UBR PF02207.15 EER24696.1 - 6.1e-17 61.0 2.7 6.1e-17 61.0 1.9 3.3 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) F-box PF00646.28 EER24697.1 - 0.073 12.7 1.3 0.2 11.3 0.9 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EER24697.1 - 0.31 10.8 1.8 1.1 8.9 1.2 2.0 1 1 0 1 1 1 0 F-box-like Meth_synt_2 PF01717.13 EER24698.1 - 0.068 12.1 0.0 0.089 11.7 0.0 1.1 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain Meth_synt_2 PF01717.13 EER24699.1 - 3.1e-10 39.5 0.0 5.5e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EER24699.1 - 0.0079 15.5 0.0 0.039 13.2 0.0 2.0 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain Arf PF00025.16 EER24700.1 - 7.8e-74 246.6 0.2 9.1e-74 246.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EER24700.1 - 2.7e-12 46.3 0.0 2.9e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EER24700.1 - 1.7e-11 43.7 0.0 2.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EER24700.1 - 2.1e-11 43.1 1.5 7.6e-08 31.4 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EER24700.1 - 4.8e-11 42.2 0.0 6.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EER24700.1 - 7.8e-07 29.6 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EER24700.1 - 0.00021 21.2 0.0 0.00029 20.7 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EER24700.1 - 0.021 13.9 0.2 0.041 12.9 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Hexapep_2 PF14602.1 EER24701.1 - 4.4e-06 26.1 3.6 0.00021 20.8 0.9 3.0 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EER24701.1 - 4.5e-06 25.9 10.2 0.00036 19.9 2.4 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EER24701.1 - 0.071 11.6 0.1 0.093 11.2 0.1 1.1 1 0 0 1 1 1 0 L-fucokinase An_peroxidase PF03098.10 EER24702.1 - 1.5e-105 353.6 0.0 1.5e-103 347.0 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EER24702.1 - 5.5e-12 44.9 0.0 1.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 EER24703.1 - 1.4e-105 352.6 0.9 1.9e-105 352.2 0.6 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) MARVEL PF01284.18 EER24704.1 - 1.6e-05 24.7 16.6 0.00016 21.5 11.9 2.0 1 1 1 2 2 2 1 Membrane-associating domain DUF4231 PF14015.1 EER24704.1 - 5.7 6.9 7.6 3.5 7.6 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) PGA2 PF07543.7 EER24705.1 - 1.3e-38 131.9 0.8 1.5e-38 131.7 0.5 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF3245 PF11595.3 EER24705.1 - 0.016 15.4 5.6 0.016 15.4 3.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) CENP-S PF15630.1 EER24706.1 - 6.8e-24 83.8 0.0 1.1e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Nop14 PF04147.7 EER24706.1 - 0.73 7.6 10.5 0.86 7.4 7.3 1.0 1 0 0 1 1 1 0 Nop14-like family Tom22 PF04281.8 EER24706.1 - 4.2 6.9 10.5 13 5.3 3.7 2.1 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 MMS1_N PF10433.4 EER24707.1 - 3.6e-78 262.9 0.0 1.8e-77 260.5 0.0 2.2 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EER24707.1 - 7.7e-72 242.0 0.0 5.8e-70 235.9 0.0 3.1 3 1 0 3 3 3 1 CPSF A subunit region PQQ_2 PF13360.1 EER24707.1 - 0.095 12.1 0.1 4.3 6.7 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain NAD_binding_2 PF03446.10 EER24708.1 - 4.5e-36 124.1 0.0 7.5e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EER24708.1 - 6.3e-31 106.9 0.0 1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EER24708.1 - 7e-06 26.3 0.0 2.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EER24708.1 - 0.0014 17.4 0.0 0.0028 16.4 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TPP_enzyme_M PF00205.17 EER24708.1 - 0.0044 16.7 0.0 0.2 11.3 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain GFO_IDH_MocA PF01408.17 EER24708.1 - 0.0048 17.4 0.0 0.0099 16.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EER24708.1 - 0.005 16.0 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ABC_membrane PF00664.18 EER24709.1 - 1.1e-85 287.4 31.4 2.1e-43 148.7 8.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EER24709.1 - 6.8e-62 207.7 0.0 3.6e-31 108.2 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EER24709.1 - 3e-16 59.3 0.8 3e-06 26.6 0.2 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER24709.1 - 3.8e-13 50.0 0.0 0.005 16.8 0.0 4.2 2 2 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EER24709.1 - 2.4e-09 37.4 0.2 0.00088 19.3 0.0 3.6 4 0 0 4 4 4 2 AAA ATPase domain ABC_ATPase PF09818.4 EER24709.1 - 2.1e-08 33.1 0.1 0.0037 15.8 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EER24709.1 - 3.9e-08 32.6 0.0 0.01 14.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EER24709.1 - 1.6e-07 31.5 0.2 0.085 13.0 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EER24709.1 - 2.6e-07 31.4 0.0 0.02 15.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EER24709.1 - 9.3e-07 28.4 0.2 0.091 12.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 EER24709.1 - 1.5e-06 28.4 1.2 0.087 13.0 0.1 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EER24709.1 - 5.8e-06 25.7 0.2 0.0065 15.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.10 EER24709.1 - 3.7e-05 22.6 0.0 0.088 11.4 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EER24709.1 - 0.00011 22.0 0.0 0.93 9.3 0.0 3.7 4 0 0 4 4 4 2 AAA domain ATP-synt_ab PF00006.20 EER24709.1 - 0.00012 21.7 0.1 0.1 12.0 0.1 3.1 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.1 EER24709.1 - 0.00015 21.6 1.3 0.14 12.1 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EER24709.1 - 0.0003 19.9 0.0 0.25 10.3 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EER24709.1 - 0.00041 20.0 0.0 2.7 7.7 0.0 3.6 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 EER24709.1 - 0.00071 19.9 0.0 2.1 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EER24709.1 - 0.0019 18.2 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EER24709.1 - 0.0025 18.1 0.1 3.6 7.9 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_30 PF13604.1 EER24709.1 - 0.0034 16.9 0.1 4.8 6.7 0.0 3.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EER24709.1 - 0.0041 17.2 0.0 8.2 6.6 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.1 EER24709.1 - 0.014 15.2 0.0 5 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 EER24709.1 - 0.016 14.8 0.0 6.9 6.3 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EER24709.1 - 0.044 12.6 0.0 1.2 7.8 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.7 EER24709.1 - 0.063 12.3 0.0 1.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.13 EER24709.1 - 0.068 12.7 0.0 8.5 5.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 EER24709.1 - 0.069 12.5 0.0 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VirE PF05272.6 EER24709.1 - 0.17 11.3 0.0 21 4.5 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E DUF724 PF05266.9 EER24710.1 - 0.0011 18.6 6.8 0.0011 18.6 4.7 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF724) DUF3138 PF11336.3 EER24710.1 - 0.36 8.9 1.5 0.42 8.7 0.3 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) Reo_sigmaC PF04582.7 EER24710.1 - 0.45 9.6 4.2 0.38 9.8 1.4 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4600 PF15372.1 EER24710.1 - 1.8 8.7 17.9 0.85 9.8 3.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) V_ATPase_I PF01496.14 EER24710.1 - 2.4 5.9 15.0 1 7.1 6.1 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 EER24710.1 - 2.9 7.7 23.4 0.69 9.7 4.4 3.8 2 1 2 4 4 4 0 Tropomyosin like DUF904 PF06005.7 EER24710.1 - 4 7.8 19.4 0.2 11.9 1.6 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF904) FtsJ PF01728.14 EER24711.1 - 4.3e-61 206.0 0.0 5.2e-61 205.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EER24711.1 - 3.7e-05 23.5 0.0 7.3e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER24711.1 - 6.6e-05 23.4 0.0 0.00016 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER24711.1 - 0.015 14.8 0.0 3.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EER24711.1 - 0.086 13.3 0.0 12 6.4 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain OST3_OST6 PF04756.8 EER24712.1 - 7.6e-21 74.3 3.2 1.2e-20 73.6 2.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EER24712.1 - 0.00093 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin NADH-u_ox-rdase PF10785.4 EER24712.1 - 0.015 15.4 2.3 0.16 12.2 0.0 2.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF2929 PF11151.3 EER24712.1 - 0.025 14.6 1.9 5.2 7.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) DUF768 PF05589.6 EER24712.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF768) VIT1 PF01988.14 EER24712.1 - 7.6 5.9 12.6 0.86 9.0 2.2 2.1 1 1 1 2 2 2 0 VIT family Acetyltransf_1 PF00583.19 EER24713.1 - 8.1e-10 38.6 0.0 3e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER24713.1 - 3.3e-09 36.7 0.0 8.6e-09 35.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER24713.1 - 6.9e-06 25.9 0.0 1.8e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER24713.1 - 0.00066 19.7 0.0 0.0072 16.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Pneumo_M2 PF07380.6 EER24713.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 Pneumovirus M2 protein FR47 PF08445.5 EER24713.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.1 EER24713.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GNAT_acetyltr_2 PF13718.1 EER24713.1 - 0.061 12.6 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 SPX PF03105.14 EER24716.1 - 1.4e-33 116.9 0.0 2.3e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EER24716.1 - 3.3e-07 30.0 9.6 3.3e-07 30.0 6.6 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EER24716.1 - 6.6e-06 25.8 10.2 2e-05 24.3 7.0 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EER24716.1 - 1.6e-05 24.4 9.2 4e-05 23.2 6.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER24716.1 - 2.6e-05 23.7 10.2 2.6e-05 23.7 7.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER24716.1 - 0.00017 21.5 11.1 0.00017 21.5 7.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER24716.1 - 0.00062 19.4 9.1 0.0018 17.9 6.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EER24716.1 - 0.013 15.1 6.7 0.013 15.1 4.6 2.5 3 0 0 3 3 3 0 RING-type zinc-finger TerY-C PF15616.1 EER24716.1 - 0.058 13.3 1.2 0.12 12.2 0.9 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain zf-P11 PF03854.9 EER24716.1 - 0.84 9.1 10.0 0.69 9.4 3.2 2.5 1 1 1 2 2 2 0 P-11 zinc finger DnaJ PF00226.26 EER24717.1 - 4.9e-24 83.8 0.2 1.1e-23 82.6 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain zf-met PF12874.2 EER24717.1 - 1.1e-09 38.1 8.0 4.1e-09 36.3 1.4 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EER24717.1 - 2.1e-09 37.2 4.5 2.1e-09 37.2 3.1 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EER24717.1 - 7.1e-06 26.0 9.6 0.00043 20.3 1.6 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EER24717.1 - 0.0014 18.4 10.2 0.15 11.9 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EER24717.1 - 0.0014 18.8 13.3 0.026 14.8 1.1 3.2 3 0 0 3 3 2 2 Zinc finger, C2H2 type CpXC PF14353.1 EER24717.1 - 0.044 13.7 5.6 4 7.4 2.5 2.6 2 1 0 2 2 2 0 CpXC protein Trm112p PF03966.11 EER24717.1 - 0.074 13.4 0.0 0.51 10.7 0.0 2.4 1 1 1 2 2 2 0 Trm112p-like protein zf-H2C2_2 PF13465.1 EER24717.1 - 0.14 12.5 1.6 0.94 9.8 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER24717.1 - 0.16 12.3 9.0 0.25 11.7 0.6 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger LIM PF00412.17 EER24717.1 - 2 8.5 5.0 1 9.5 0.4 2.4 2 0 0 2 2 2 0 LIM domain DUF2387 PF09526.5 EER24717.1 - 3.2 7.7 6.5 1.5 8.8 1.6 2.5 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) R3H PF01424.17 EER24718.1 - 3.1e-11 42.7 0.0 7.2e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EER24718.1 - 2.1e-07 30.5 0.6 4.2e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 G-patch domain CENP-B_dimeris PF09026.5 EER24718.1 - 0.0087 16.2 6.8 0.024 14.8 4.7 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EER24718.1 - 0.014 15.6 3.3 0.014 15.6 2.3 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EER24718.1 - 0.078 12.4 5.0 0.16 11.4 3.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 EER24718.1 - 0.24 11.2 7.5 0.41 10.4 5.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rad60-SLD PF11976.3 EER24719.1 - 9.5e-20 70.0 0.1 3.6e-19 68.2 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EER24719.1 - 0.029 13.7 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family Trm112p PF03966.11 EER24720.1 - 8e-16 58.1 0.1 9.7e-16 57.8 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EER24720.1 - 0.051 13.8 0.2 0.093 13.0 0.2 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain DUF1451 PF07295.6 EER24720.1 - 0.29 10.9 1.4 0.51 10.1 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) N-SET PF11764.3 EER24721.1 - 3.4e-50 170.2 1.5 8.9e-50 168.8 1.0 1.8 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EER24721.1 - 5.7e-28 96.0 0.5 1e-27 95.1 0.4 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EER24721.1 - 2.2e-24 86.6 1.0 1.3e-23 84.1 0.1 2.8 2 1 0 2 2 2 1 SET domain RRM_1 PF00076.17 EER24721.1 - 0.00026 20.5 0.0 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SIS PF01380.17 EER24723.1 - 1.3e-53 180.1 0.0 2.6e-30 104.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EER24723.1 - 1.3e-27 96.4 0.0 3.4e-18 65.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EER24723.1 - 1.6e-19 70.1 0.0 3.3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EER24723.1 - 7.2e-12 45.1 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EER24723.1 - 3.5e-07 29.2 0.2 7.6e-07 28.0 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EER24723.1 - 0.1 12.2 0.0 0.49 10.1 0.0 2.1 2 0 0 2 2 2 0 SIS domain DMRL_synthase PF00885.14 EER24724.1 - 2.2e-42 144.1 0.5 2.4e-24 85.6 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 EER24725.1 - 1.4e-45 154.9 0.3 1.9e-31 108.8 0.0 2.5 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EER24725.1 - 8.6e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Lar_restr_allev PF14354.1 EER24726.1 - 0.015 15.6 0.5 0.051 13.8 0.1 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EER24726.1 - 0.45 9.7 3.6 5.6 6.3 2.5 2.4 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EER24726.1 - 0.59 9.7 3.0 3.2 7.3 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Iso_dh PF00180.15 EER24727.1 - 6.6e-84 281.8 0.1 8.4e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Erv26 PF04148.8 EER24728.1 - 1.6e-88 295.6 0.1 1.8e-88 295.4 0.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 WBS_methylT PF12589.3 EER24729.1 - 3.3e-18 65.9 1.8 5.5e-18 65.2 1.2 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EER24729.1 - 4.5e-10 39.8 0.0 7.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER24729.1 - 7.9e-08 32.5 0.0 1.9e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER24729.1 - 9.7e-06 25.2 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER24729.1 - 1.7e-05 25.3 0.0 5.1e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER24729.1 - 0.00013 22.3 0.0 0.00032 21.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER24729.1 - 0.00021 21.0 0.0 0.00031 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EER24729.1 - 0.00034 20.2 0.0 0.00058 19.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EER24729.1 - 0.0011 18.9 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER24729.1 - 0.011 14.8 0.0 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EER24729.1 - 0.087 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RhoGAP PF00620.22 EER24730.1 - 2.5e-40 137.5 0.1 5.7e-40 136.3 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EER24730.1 - 5.9e-09 36.0 0.0 1.4e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EER24730.1 - 3.6e-06 27.1 0.0 8.9e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.19 EER24730.1 - 0.0082 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 PX domain PH_8 PF15409.1 EER24730.1 - 0.042 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain IncA PF04156.9 EER24730.1 - 2.5 7.6 6.6 0.16 11.5 0.3 1.9 2 0 0 2 2 2 0 IncA protein MDM31_MDM32 PF08118.6 EER24731.1 - 3.6e-200 665.7 0.2 4.3e-200 665.4 0.2 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins KH_1 PF00013.24 EER24732.1 - 0.00063 19.3 1.9 0.0013 18.2 1.3 1.5 1 0 0 1 1 1 1 KH domain Proteasome PF00227.21 EER24733.1 - 2.1e-31 108.7 0.1 1.2e-30 106.2 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 EER24734.1 - 5.8e-26 90.3 0.1 1.1e-25 89.4 0.1 1.4 1 0 0 1 1 1 1 HCNGP-like protein DUF605 PF04652.11 EER24734.1 - 0.38 10.1 9.1 0.4 10.0 6.3 1.2 1 0 0 1 1 1 0 Vta1 like Proteasome PF00227.21 EER24735.1 - 1.3e-28 99.5 0.0 1.5e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.13 EER24736.1 - 1.4e-61 207.7 0.0 1.8e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 EER24737.1 - 4.2e-19 68.0 3.4 5.6e-19 67.6 2.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EER24737.1 - 3.8e-16 59.0 2.9 4.7e-16 58.7 2.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EER24737.1 - 0.00088 19.7 0.4 0.0011 19.3 0.3 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Ferritin_2 PF13668.1 EER24738.1 - 9.1e-17 61.2 0.4 1.4e-16 60.7 0.3 1.2 1 0 0 1 1 1 1 Ferritin-like domain RRM_5 PF13893.1 EER24739.1 - 4e-09 36.2 0.1 5.5e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER24739.1 - 3.1e-08 33.1 0.1 6.7e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER24739.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EER24740.1 - 1.8e-20 71.9 4.7 9e-07 28.5 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EER24740.1 - 0.0016 17.7 0.0 0.0041 16.3 0.0 1.6 2 0 0 2 2 2 1 Cortical protein marker for cell polarity TA0956 PF11513.3 EER24740.1 - 0.097 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 Lipase_3 PF01764.20 EER24741.1 - 5.7e-33 113.4 0.0 9.4e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EER24741.1 - 0.038 13.7 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EER24741.1 - 0.04 14.1 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Cutinase PF01083.17 EER24741.1 - 0.045 13.4 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 EER24741.1 - 0.063 12.6 0.0 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 EER24741.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold WW PF00397.21 EER24742.1 - 6e-09 35.6 0.6 1.4e-08 34.4 0.4 1.7 1 0 0 1 1 1 1 WW domain Chlorosome_CsmC PF11098.3 EER24742.1 - 0.38 10.4 2.1 0.92 9.2 1.4 1.6 1 0 0 1 1 1 0 Chlorosome envelope protein C Ecm29 PF13001.2 EER24743.1 - 6.4e-154 513.1 0.2 6.4e-154 513.1 0.1 2.1 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 EER24743.1 - 5.4e-05 22.9 10.7 2.4 8.4 0.0 9.4 11 0 0 11 11 11 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EER24743.1 - 0.002 18.4 6.9 14 6.1 0.1 6.1 6 1 0 6 6 6 2 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 EER24743.1 - 0.0075 16.2 0.7 0.078 12.9 0.1 3.1 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation SIR2_2 PF13289.1 EER24743.1 - 0.054 13.3 0.0 9 6.1 0.0 2.7 2 0 0 2 2 2 0 SIR2-like domain HEAT_EZ PF13513.1 EER24743.1 - 0.23 12.0 15.3 13 6.4 0.0 8.1 9 1 1 10 10 10 0 HEAT-like repeat Frag1 PF10277.4 EER24744.1 - 2e-44 151.6 11.1 2.3e-44 151.4 7.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family YHYH PF14240.1 EER24744.1 - 0.098 12.3 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 YHYH protein DnaJ PF00226.26 EER24746.1 - 1.3e-12 47.2 1.3 2.9e-12 46.1 0.2 2.1 2 1 0 2 2 2 1 DnaJ domain DnaJ PF00226.26 EER24748.1 - 4.2e-07 29.6 0.8 7.9e-07 28.7 0.2 1.7 2 0 0 2 2 2 1 DnaJ domain DUF456 PF04306.8 EER24748.1 - 0.00052 20.0 0.5 0.00068 19.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 EER24748.1 - 0.01 15.4 0.9 0.014 15.0 0.6 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain WHG PF13305.1 EER24748.1 - 0.037 14.6 0.0 0.078 13.5 0.0 1.6 1 0 0 1 1 1 0 WHG domain Rick_17kDa_Anti PF05433.10 EER24748.1 - 0.079 12.6 1.0 0.079 12.6 0.7 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain MFS_1 PF07690.11 EER24749.1 - 1.8e-36 125.6 60.2 1.8e-36 125.6 41.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily PMM PF03332.8 EER24750.1 - 1.7e-102 341.6 0.2 2e-102 341.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EER24750.1 - 0.0003 20.4 0.0 0.0012 18.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EER24750.1 - 0.091 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein F-box-like PF12937.2 EER24751.1 - 1.8e-08 33.9 1.2 8.6e-08 31.7 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EER24751.1 - 0.00015 21.3 0.1 0.00056 19.4 0.1 2.0 1 0 0 1 1 1 1 F-box domain DUF1640 PF07798.6 EER24752.1 - 3.3e-63 212.9 3.8 4.1e-63 212.6 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) SNF2_N PF00176.18 EER24754.1 - 1.6e-53 181.4 0.0 4e-53 180.1 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER24754.1 - 0.00043 20.0 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER24754.1 - 0.027 14.3 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3812 PF12757.2 EER24755.1 - 2.4e-31 108.3 3.9 2.4e-31 108.3 2.7 4.3 3 1 1 4 4 4 2 Protein of unknown function (DUF3812) DUF3527 PF12043.3 EER24755.1 - 1.7 8.0 7.1 0.16 11.4 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) Pkinase PF00069.20 EER24756.1 - 1.5e-68 230.7 0.0 1.5e-68 230.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24756.1 - 5e-42 143.7 0.0 7.4e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER24756.1 - 2.3e-10 39.9 0.0 5e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EER24756.1 - 0.0041 16.2 0.7 0.063 12.3 0.0 2.3 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER24756.1 - 0.018 14.7 7.2 1.9 8.1 0.1 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EER24756.1 - 1.6 8.0 4.9 0.7 9.2 0.0 2.4 2 0 0 2 2 2 0 RIO1 family AMP-binding PF00501.23 EER24757.1 - 3.3e-73 246.4 0.3 4.9e-73 245.8 0.2 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EER24757.1 - 3.4e-66 223.1 0.0 5.1e-35 120.7 0.0 2.4 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EER24757.1 - 1.2e-19 70.3 1.5 1.5e-09 37.9 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EER24757.1 - 0.038 14.2 0.0 0.18 12.1 0.0 2.2 1 0 0 1 1 1 0 HxxPF-repeated domain FAD_binding_3 PF01494.14 EER24758.1 - 5.9e-09 35.4 0.1 1.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EER24758.1 - 4.4e-05 22.5 0.0 6.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF4434 PF14488.1 EER24758.1 - 0.0043 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) SE PF08491.5 EER24758.1 - 0.058 12.2 0.0 0.14 10.9 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Trp_DMAT PF11991.3 EER24759.1 - 4.7e-93 312.2 0.0 6e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF3246 PF11596.3 EER24760.1 - 0.0025 17.1 16.8 0.0037 16.5 11.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Nucleoplasmin PF03066.10 EER24760.1 - 0.12 11.8 10.0 1.4 8.4 2.2 2.2 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 EER24760.1 - 0.37 11.1 15.7 2 8.7 1.5 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 EER24760.1 - 1.9 8.6 14.6 3.5 7.8 1.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) ANAPC15 PF15243.1 EER24760.1 - 4.4 7.4 8.3 6.8 6.8 1.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Ebola_NP PF05505.7 EER24760.1 - 9.1 4.1 7.2 12 3.8 5.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Prenyltrans PF00432.16 EER24761.1 - 2.1e-26 91.1 14.3 4.6e-08 32.4 0.2 6.3 6 1 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EER24761.1 - 3.5e-22 78.9 0.1 6.2e-18 65.2 0.0 3.0 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EER24761.1 - 1.2e-06 28.4 0.5 0.041 13.8 0.0 3.9 2 2 3 5 5 5 2 Prenyltransferase-like Ilm1 PF10311.4 EER24762.1 - 6.3e-27 94.1 0.2 8.8e-27 93.6 0.2 1.2 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 CFEM PF05730.6 EER24763.1 - 1.4e-14 53.6 12.8 3e-14 52.5 8.9 1.6 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.11 EER24764.1 - 2.4e-31 108.7 21.7 2.4e-31 108.7 15.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER24764.1 - 5.3e-06 25.2 14.5 5.3e-06 25.2 10.0 4.1 3 2 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 EER24765.1 - 1.8e-06 26.9 14.6 1.8e-06 26.9 10.1 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Tyrosinase PF00264.15 EER24767.1 - 1.7e-28 100.3 0.0 1.2e-27 97.5 0.0 2.1 1 1 1 2 2 2 1 Common central domain of tyrosinase E1-E2_ATPase PF00122.15 EER24769.1 - 6.1e-65 218.4 6.6 6.1e-65 218.4 4.6 3.3 4 1 1 5 5 5 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EER24769.1 - 2.1e-45 154.4 9.8 2.1e-45 154.4 6.8 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EER24769.1 - 6.3e-30 105.2 0.0 3e-29 102.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER24769.1 - 3.9e-22 78.0 0.0 1.4e-21 76.1 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EER24769.1 - 1.4e-20 72.5 0.0 4e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EER24769.1 - 1.1e-15 58.3 0.0 8.7e-15 55.3 0.0 2.5 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER24769.1 - 4.4e-08 33.0 1.4 7.2e-06 25.7 0.6 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EER24769.1 - 0.043 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase 14-3-3 PF00244.15 EER24770.1 - 1e-114 381.5 2.8 1.2e-114 381.2 1.9 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EER24770.1 - 0.005 16.3 0.4 8.6 5.8 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF837) TPR_12 PF13424.1 EER24770.1 - 0.0063 16.4 0.3 1.9 8.4 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat HisKA PF00512.20 EER24770.1 - 0.085 12.8 0.1 17 5.4 0.0 2.8 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain CAP18_C PF12153.3 EER24770.1 - 0.16 11.6 0.1 0.27 10.9 0.1 1.3 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) MCM_N PF14551.1 EER24770.1 - 0.36 11.3 2.6 9.8 6.6 1.8 2.3 1 1 0 1 1 1 0 MCM N-terminal domain eIF3_subunit PF08597.5 EER24771.1 - 6.4e-71 238.7 28.5 7.1e-71 238.6 19.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ARGLU PF15346.1 EER24771.1 - 3.6 7.3 25.3 2.2 8.0 13.6 2.2 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Enolase_C PF00113.17 EER24772.1 - 2.2e-151 502.8 0.0 3.1e-151 502.4 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EER24772.1 - 9.8e-57 190.5 0.4 1.6e-56 189.8 0.3 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EER24772.1 - 0.00062 18.7 1.1 0.012 14.6 0.1 2.7 3 0 0 3 3 3 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EER24772.1 - 0.03 14.8 0.0 0.065 13.7 0.0 1.6 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 EER24772.1 - 0.074 13.0 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like Thioredoxin_8 PF13905.1 EER24772.1 - 0.096 12.8 0.7 0.18 11.9 0.5 1.5 1 0 0 1 1 1 0 Thioredoxin-like AAA PF00004.24 EER24773.1 - 4.6e-43 146.5 0.0 8.9e-43 145.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER24773.1 - 9.7e-08 32.1 0.0 4.5e-06 26.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EER24773.1 - 1.5e-06 27.9 0.1 3.8e-05 23.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EER24773.1 - 2.1e-06 27.7 0.0 7.8e-06 25.9 0.0 2.0 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EER24773.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EER24773.1 - 7.1e-06 25.2 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EER24773.1 - 0.00012 21.0 0.0 0.00052 19.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EER24773.1 - 0.00035 20.2 0.0 0.0008 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EER24773.1 - 0.00073 20.3 0.6 0.0019 18.9 0.1 2.2 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EER24773.1 - 0.0013 18.6 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER24773.1 - 0.0017 18.2 0.0 0.0063 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EER24773.1 - 0.0017 17.1 0.0 0.0031 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EER24773.1 - 0.0021 18.3 0.2 0.0082 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EER24773.1 - 0.0026 17.1 0.0 0.0052 16.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EER24773.1 - 0.0038 16.4 0.0 0.0071 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF4200 PF13863.1 EER24773.1 - 0.004 17.0 1.7 0.004 17.0 1.2 1.8 2 0 0 2 2 1 1 Domain of unknown function (DUF4200) Zeta_toxin PF06414.7 EER24773.1 - 0.0048 16.0 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EER24773.1 - 0.005 16.9 0.0 0.0097 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Sigma54_activat PF00158.21 EER24773.1 - 0.0073 15.7 0.0 0.026 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_11 PF13086.1 EER24773.1 - 0.008 15.7 0.3 0.26 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EER24773.1 - 0.0093 15.5 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EER24773.1 - 0.0099 15.2 0.1 0.061 12.7 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 EER24773.1 - 0.018 14.6 0.1 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EER24773.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EER24773.1 - 0.022 14.8 0.0 0.065 13.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain ResIII PF04851.10 EER24773.1 - 0.022 14.5 0.0 0.062 13.1 0.0 1.8 2 0 0 2 2 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EER24773.1 - 0.024 14.3 0.2 0.14 11.8 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase Thymidylate_kin PF02223.12 EER24773.1 - 0.025 13.9 0.1 1.4 8.2 0.0 2.6 3 0 0 3 3 2 0 Thymidylate kinase KaiC PF06745.8 EER24773.1 - 0.029 13.4 0.4 0.11 11.5 0.0 2.2 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 EER24773.1 - 0.029 13.5 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EER24773.1 - 0.04 13.5 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EER24773.1 - 0.051 13.2 0.0 0.098 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EER24773.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EER24773.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MscS_porin PF12795.2 EER24773.1 - 0.1 11.8 2.9 0.51 9.6 2.5 1.8 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain AAA_23 PF13476.1 EER24773.1 - 0.48 10.7 8.4 2.9 8.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Glyco_hydro_47 PF01532.15 EER24774.1 - 7.1e-165 549.0 0.0 8.4e-165 548.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EER24774.1 - 0.001 18.4 0.0 0.0024 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) M20_dimer PF07687.9 EER24775.1 - 1.4e-20 73.0 0.2 1.3e-18 66.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EER24775.1 - 1.1e-17 64.1 0.1 1.6e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 TRAP_alpha PF03896.11 EER24776.1 - 5.5e-14 51.8 0.5 1.3e-13 50.5 0.3 1.6 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit zf-CCCH_2 PF14608.1 EER24777.1 - 9.8 6.3 12.8 0.059 13.4 1.2 3.0 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type POT1 PF02765.12 EER24778.1 - 1.6e-15 57.3 0.0 1.3e-13 51.0 0.0 2.3 2 0 0 2 2 2 2 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EER24778.1 - 0.0082 15.9 0.0 25 4.8 0.0 3.4 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Arm PF00514.18 EER24779.1 - 7.5e-92 298.4 9.8 3.6e-14 51.9 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EER24779.1 - 3.6e-25 88.0 0.0 1.1e-09 38.4 0.0 5.6 1 1 5 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 EER24779.1 - 1.6e-23 82.5 3.7 4.3e-10 39.7 0.1 5.5 4 1 2 6 6 6 4 HEAT-like repeat HEAT PF02985.17 EER24779.1 - 1.1e-21 74.8 0.0 1.2e-06 28.0 0.0 6.6 6 0 0 6 6 6 4 HEAT repeat IBB PF01749.15 EER24779.1 - 8.4e-21 73.9 2.0 1.4e-20 73.2 1.4 1.4 1 0 0 1 1 1 1 Importin beta binding domain Arm_2 PF04826.8 EER24779.1 - 2.5e-11 43.2 0.0 0.0006 18.9 0.0 4.1 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EER24779.1 - 5.5e-05 21.6 0.0 0.029 12.6 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EER24779.1 - 9e-05 22.3 0.0 0.65 9.9 0.0 4.4 4 1 0 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EER24779.1 - 0.0016 16.7 0.0 0.1 10.8 0.0 2.7 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 EER24779.1 - 0.0028 17.9 4.1 0.81 10.3 0.0 4.8 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Glycos_trans_3N PF02885.12 EER24779.1 - 0.1 12.1 0.0 66 3.1 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain SURF6 PF04935.7 EER24779.1 - 3.8 6.7 7.5 5.6 6.1 5.2 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 Amidase PF01425.16 EER24780.1 - 2.1e-106 356.4 0.0 2.5e-106 356.2 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EER24781.1 - 6.3e-32 110.6 28.4 6.3e-32 110.6 19.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily SLAC1 PF03595.12 EER24782.1 - 3.7e-95 318.3 60.7 4.1e-95 318.1 42.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel PetM PF08041.6 EER24782.1 - 2.5 7.6 8.1 4.5 6.8 2.3 3.2 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 MoaE PF02391.12 EER24783.1 - 7.9e-27 93.3 0.0 9.6e-27 93.1 0.0 1.1 1 0 0 1 1 1 1 MoaE protein SCO1-SenC PF02630.9 EER24784.1 - 2e-57 193.5 0.0 2.7e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EER24784.1 - 0.0046 16.6 0.0 0.0084 15.7 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EER24784.1 - 0.01 15.9 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like UPF0184 PF03670.8 EER24785.1 - 0.00025 21.1 0.2 0.3 11.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0184) Yae1_N PF09811.4 EER24787.1 - 1.1e-13 50.4 0.1 1.5e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF605 PF04652.11 EER24787.1 - 0.39 10.0 3.9 0.4 10.0 2.7 1.1 1 0 0 1 1 1 0 Vta1 like CBM_21 PF03370.8 EER24788.1 - 6.2e-27 93.8 1.3 1.1e-26 92.9 0.9 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Acetyltransf_3 PF13302.1 EER24789.1 - 9.7e-32 110.0 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER24789.1 - 3.5e-05 23.7 0.2 8.5e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EER24789.1 - 0.001 18.9 0.0 0.0014 18.5 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER24789.1 - 0.02 14.8 0.0 0.054 13.4 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER24789.1 - 0.055 13.6 0.1 0.098 12.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-RanBP PF00641.13 EER24791.1 - 1.1e-10 40.3 1.3 2.6e-10 39.2 0.9 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch PF01585.18 EER24791.1 - 7.6e-10 38.4 3.1 2.6e-09 36.7 2.2 2.0 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EER24791.1 - 2.5e-09 36.9 0.0 0.00052 19.9 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER24791.1 - 3.6e-09 36.1 0.0 0.00035 20.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EER24791.1 - 5.8e-07 29.2 1.0 2.7e-06 27.1 0.7 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site Rad50_zn_hook PF04423.9 EER24791.1 - 0.016 14.6 0.4 0.062 12.7 0.3 2.0 1 0 0 1 1 1 0 Rad50 zinc hook motif RRM_5 PF13893.1 EER24791.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3433 PF11915.3 EER24792.1 - 1.2e-31 108.6 13.0 1.1e-26 92.8 2.3 3.7 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF1180 PF06679.7 EER24793.1 - 0.95 9.3 0.0 0.95 9.3 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1180) Glyco_hydro_18 PF00704.23 EER24794.1 - 1.1e-13 51.3 0.7 2.1e-12 47.1 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Peptidase_M35 PF02102.10 EER24795.1 - 4.8e-108 361.0 2.6 5.5e-108 360.8 1.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EER24795.1 - 0.0018 18.7 0.4 0.003 18.0 0.3 1.3 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Imm42 PF15601.1 EER24795.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 42 PsaN PF05479.6 EER24795.1 - 1.1 9.2 4.5 1.3 9.0 1.9 1.9 2 0 0 2 2 2 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) ECH PF00378.15 EER24798.1 - 1.8e-34 118.9 0.0 4.5e-34 117.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Tbf5 PF06331.7 EER24799.1 - 8.2e-26 89.5 1.0 9.1e-26 89.4 0.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 EER24799.1 - 0.092 12.3 0.2 0.098 12.2 0.2 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain Aa_trans PF01490.13 EER24800.1 - 4.3e-36 124.2 29.3 5.8e-36 123.8 20.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EER24800.1 - 0.0014 17.5 17.9 0.0014 17.5 12.4 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family CAAD PF14159.1 EER24800.1 - 0.028 14.0 1.3 0.028 14.0 0.9 3.6 3 1 1 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase PHO4 PF01384.15 EER24801.1 - 2.2e-108 361.8 9.7 2.6e-108 361.5 6.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.13 EER24801.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A Tim17 PF02466.14 EER24801.1 - 0.13 12.3 10.3 0.34 10.9 0.1 4.1 4 0 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family COesterase PF00135.23 EER24802.1 - 1.8e-89 300.8 4.3 6.2e-81 272.7 0.2 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EER24802.1 - 2.1e-08 33.9 0.0 3.3e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold HlyIII PF03006.15 EER24803.1 - 0.065 12.6 0.3 0.099 12.0 0.2 1.3 1 0 0 1 1 1 0 Haemolysin-III related Beta-lactamase PF00144.19 EER24805.1 - 2.7e-13 49.6 0.0 4.8e-13 48.8 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase Kelch_2 PF07646.10 EER24805.1 - 0.055 13.2 0.1 0.099 12.4 0.1 1.5 1 0 0 1 1 1 0 Kelch motif Pyr_redox_3 PF13738.1 EER24806.1 - 4.7e-10 39.8 0.0 1.2e-08 35.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER24806.1 - 4e-05 22.0 0.0 0.00014 20.2 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EER24806.1 - 0.0019 18.1 0.0 0.0093 15.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EER24806.1 - 0.074 13.1 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1601 PF07671.6 EER24807.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) HET PF06985.6 EER24808.1 - 1.8e-08 34.6 0.1 7e-07 29.4 0.1 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 EER24809.1 - 3.2e-15 56.5 0.1 6.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER24809.1 - 0.035 13.6 0.0 0.16 11.5 0.0 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase AIG2 PF06094.7 EER24810.1 - 4.2e-12 46.4 0.0 5.9e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family APH PF01636.18 EER24811.1 - 6.4e-17 62.0 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER24811.1 - 0.0077 15.8 0.0 0.012 15.2 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase HSP70 PF00012.15 EER24812.1 - 6.6e-12 44.1 0.2 5.6e-07 27.8 0.1 2.9 1 1 1 2 2 2 2 Hsp70 protein MpPF1 PF07668.6 EER24812.1 - 0.1 11.7 0.4 0.24 10.5 0.1 1.7 1 1 1 2 2 2 0 M penetrans paralogue family 1 DUF4316 PF14195.1 EER24812.1 - 0.11 12.6 0.6 15 5.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4316) UPF0542 PF15086.1 EER24813.1 - 4.5 7.0 8.4 20 4.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 ESSS PF10183.4 EER24815.1 - 0.058 13.7 2.4 0.28 11.6 1.1 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GspL_C PF12693.2 EER24815.1 - 0.17 11.6 1.4 0.26 11.0 1.0 1.3 1 0 0 1 1 1 0 GspL periplasmic domain Zn_clus PF00172.13 EER24816.1 - 0.057 13.3 9.9 0.12 12.3 6.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup160 PF11715.3 EER24818.1 - 1.2e-108 363.6 0.7 1.6e-108 363.2 0.5 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 SIR2 PF02146.12 EER24819.1 - 2.5e-27 95.7 0.0 9.4e-27 93.8 0.0 1.8 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.5 EER24819.1 - 0.91 9.5 5.2 1.8 8.5 3.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain CBFD_NFYB_HMF PF00808.18 EER24820.1 - 2.3e-07 30.7 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIA PF03153.8 EER24820.1 - 0.0012 18.8 31.2 0.0012 18.8 21.6 1.8 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit Histone PF00125.19 EER24820.1 - 0.0028 17.7 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nop14 PF04147.7 EER24820.1 - 0.11 10.4 40.0 0.15 9.9 27.7 1.2 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.5 EER24820.1 - 0.27 10.4 26.6 0.4 9.8 18.5 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 YqzE PF14038.1 EER24820.1 - 0.3 10.8 1.7 1.1 9.0 0.4 2.5 3 1 0 3 3 3 0 YqzE-like protein CENP-T PF15511.1 EER24820.1 - 0.41 9.8 29.1 1.8 7.7 19.2 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T GN3L_Grn1 PF08701.6 EER24821.1 - 1.7e-24 85.5 12.2 3.6e-24 84.4 8.4 1.6 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EER24821.1 - 3.1e-19 69.0 0.0 1.3e-13 50.9 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EER24821.1 - 3.3e-08 33.5 1.8 0.16 11.7 0.0 3.8 3 2 0 4 4 4 3 Dynamin family GTP_EFTU PF00009.22 EER24821.1 - 1.9e-06 27.4 0.0 0.028 13.8 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EER24821.1 - 0.00015 20.9 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EER24821.1 - 0.00022 20.5 0.0 0.0016 17.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EER24821.1 - 0.00084 19.8 0.0 1.7 9.1 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EER24821.1 - 0.005 16.8 0.5 0.034 14.1 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 EER24821.1 - 0.018 14.4 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EER24821.1 - 0.026 14.8 0.0 0.094 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EER24821.1 - 0.097 12.5 0.1 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Torsin TIR_2 PF13676.1 EER24821.1 - 0.14 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 TIR domain CPL PF08144.6 EER24822.1 - 3.1e-14 53.0 0.0 1.6e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 CPL (NUC119) domain Med16 PF11635.3 EER24823.1 - 6.5e-165 550.1 0.0 8.2e-165 549.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 ATP-synt_10 PF05176.9 EER24824.1 - 1.4e-83 280.0 0.0 1.7e-83 279.7 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 EER24825.1 - 9.4e-14 51.2 0.4 9.4e-14 51.2 0.3 2.5 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.1 EER24825.1 - 0.0016 17.0 4.8 0.0022 16.5 3.3 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Sec20 PF03908.8 EER24825.1 - 0.027 14.1 2.7 3.2 7.5 0.0 3.2 2 1 0 3 3 3 0 Sec20 MtrG PF04210.8 EER24825.1 - 0.04 13.5 0.4 0.11 12.2 0.3 1.8 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G ATP-synt_D PF01813.12 EER24825.1 - 0.047 13.2 2.2 0.11 12.0 1.6 1.7 1 1 0 1 1 1 0 ATP synthase subunit D HTH_20 PF12840.2 EER24825.1 - 0.053 13.3 0.6 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Surfac_D-trimer PF09006.6 EER24825.1 - 0.11 12.2 2.1 1.7 8.4 0.3 2.6 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation PEP-utilisers_N PF05524.8 EER24825.1 - 0.26 11.0 6.5 0.046 13.5 0.7 2.2 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal IncA PF04156.9 EER24825.1 - 0.7 9.4 10.5 1.4 8.4 7.3 1.5 1 0 0 1 1 1 0 IncA protein Ribosomal_L29 PF00831.18 EER24826.1 - 2.2e-18 65.7 0.4 2.2e-18 65.7 0.3 1.8 2 0 0 2 2 2 1 Ribosomal L29 protein Cortex-I_coil PF09304.5 EER24826.1 - 0.0039 17.2 3.0 0.0041 17.1 0.5 1.8 2 0 0 2 2 2 1 Cortexillin I, coiled coil Ribosomal_S9 PF00380.14 EER24826.1 - 0.086 13.0 2.2 0.13 12.5 1.5 1.5 1 1 0 1 1 1 0 Ribosomal protein S9/S16 HAD_2 PF13419.1 EER24827.1 - 2.8e-17 63.4 0.0 3.9e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EER24827.1 - 2.4e-12 47.7 0.0 8.1e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER24827.1 - 3.9e-08 32.8 0.0 1.3e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.2 EER24827.1 - 0.00019 21.6 0.0 0.00046 20.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EER24827.1 - 0.0033 17.2 0.0 0.73 9.7 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 EER24828.1 - 1.7e-16 59.5 4.2 4e-16 58.3 2.9 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EER24828.1 - 2e-05 24.2 0.6 2e-05 24.2 0.4 2.2 2 0 0 2 2 2 1 Homeobox KN domain CRC_subunit PF08624.5 EER24829.1 - 4.6e-56 188.5 0.3 6.5e-56 188.1 0.2 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SLD3 PF08639.5 EER24831.1 - 2.2e-120 402.6 2.2 3.2e-120 402.1 1.5 1.2 1 0 0 1 1 1 1 DNA replication regulator SLD3 S-AdoMet_synt_C PF02773.11 EER24832.1 - 1.3e-76 254.9 1.1 2e-76 254.2 0.3 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EER24832.1 - 2.6e-48 162.9 0.0 4.5e-48 162.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EER24832.1 - 7.3e-43 144.8 0.4 1.4e-42 143.9 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain ATP_bind_1 PF03029.12 EER24833.1 - 9.6e-75 251.1 0.0 1.1e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EER24833.1 - 2.5e-06 28.3 0.0 7.1e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EER24833.1 - 0.00023 21.0 0.0 0.00046 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EER24833.1 - 0.00025 21.1 0.0 0.00044 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EER24833.1 - 0.00056 19.8 0.0 0.0029 17.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER24833.1 - 0.00087 18.9 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 EER24833.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EER24833.1 - 0.0014 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EER24833.1 - 0.0015 18.4 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER24833.1 - 0.0023 17.9 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EER24833.1 - 0.0047 15.8 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EER24833.1 - 0.0053 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase SRP54 PF00448.17 EER24833.1 - 0.0061 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EER24833.1 - 0.0094 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EER24833.1 - 0.011 15.2 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein GTP_EFTU PF00009.22 EER24833.1 - 0.014 14.8 0.0 4 6.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EER24833.1 - 0.019 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EER24833.1 - 0.025 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EER24833.1 - 0.025 14.8 0.0 0.075 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 EER24833.1 - 0.035 14.4 0.0 0.069 13.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EER24833.1 - 0.038 13.5 0.0 0.098 12.2 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain cobW PF02492.14 EER24833.1 - 0.05 13.0 0.1 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KaiC PF06745.8 EER24833.1 - 0.05 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC CbiA PF01656.18 EER24833.1 - 0.053 12.9 0.0 0.079 12.3 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 EER24833.1 - 0.062 12.8 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EER24833.1 - 0.079 12.3 0.0 0.24 10.7 0.0 1.7 1 1 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 EER24833.1 - 0.088 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EER24833.1 - 0.096 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EER24833.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PduV-EutP PF10662.4 EER24833.1 - 0.11 12.0 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EER24833.1 - 0.12 11.3 0.0 0.12 11.3 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.10 EER24833.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 NTPase AAA_5 PF07728.9 EER24833.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ArsA_ATPase PF02374.10 EER24833.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase Septin PF00735.13 EER24833.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin Zeta_toxin PF06414.7 EER24833.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Ferric_reduct PF01794.14 EER24834.1 - 1.4e-15 57.5 16.3 1.4e-15 57.5 11.3 2.3 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EER24834.1 - 6.3e-14 52.1 0.0 8.7e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EER24834.1 - 1.3e-07 31.4 0.0 5.7e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EER24834.1 - 0.15 12.6 0.0 9.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF3296 PF11726.3 EER24835.1 - 1.4 8.4 8.2 0.29 10.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3296) V-ATPase_H_N PF03224.9 EER24836.1 - 1.8e-77 260.5 0.0 3.2e-77 259.7 0.0 1.4 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EER24836.1 - 8.3e-41 138.6 0.0 2.6e-40 137.0 0.0 1.9 1 0 0 1 1 1 1 V-ATPase subunit H TMF_TATA_bd PF12325.3 EER24837.1 - 1.1e-41 141.3 10.3 1.1e-41 141.3 7.1 6.5 2 1 6 8 8 8 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EER24837.1 - 8.6e-22 76.7 12.2 8.6e-22 76.7 8.5 8.9 5 3 4 9 9 9 1 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EER24837.1 - 0.0044 16.8 13.4 0.011 15.5 0.6 4.4 5 0 0 5 5 5 2 Baculovirus polyhedron envelope protein, PEP, C terminus Toxin-deaminase PF14424.1 EER24837.1 - 3.3 7.6 15.6 0.54 10.2 2.7 3.6 1 1 2 3 3 3 0 The BURPS668_1122 family of deaminases Ank_2 PF12796.2 EER24838.1 - 1.8e-36 124.3 1.0 4e-18 65.5 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER24838.1 - 3.8e-33 113.2 10.0 2.2e-08 34.3 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER24838.1 - 1.6e-32 110.7 9.8 1.9e-09 37.4 0.2 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EER24838.1 - 5.3e-30 101.7 1.7 3.6e-07 29.6 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_3 PF13606.1 EER24838.1 - 1.4e-24 83.7 0.7 6.5e-05 22.7 0.0 5.9 6 0 0 6 6 6 5 Ankyrin repeat Shal-type PF11601.3 EER24838.1 - 0.82 9.2 0.1 0.82 9.2 0.0 2.5 3 0 0 3 3 3 0 Shal-type voltage-gated potassium channels WD40 PF00400.27 EER24839.1 - 1.4e-55 183.3 11.8 8.3e-10 38.1 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EER24839.1 - 0.00069 17.8 4.0 8 4.4 0.0 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EER24839.1 - 0.011 15.2 0.3 2.3 7.5 0.0 2.6 2 1 0 2 2 2 0 PQQ-like domain AAA PF00004.24 EER24840.1 - 1.8e-14 54.0 0.0 3.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER24840.1 - 1.5e-09 38.1 0.0 6.6e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EER24840.1 - 5.1e-07 29.9 0.0 1.1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER24840.1 - 1e-05 25.1 0.2 3.7e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EER24840.1 - 0.0011 19.8 0.0 0.0082 16.9 0.0 2.5 3 0 0 3 3 2 1 AAA domain BAH PF01426.13 EER24840.1 - 0.0026 17.4 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_11 PF13086.1 EER24840.1 - 0.0049 16.4 0.0 0.0081 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EER24840.1 - 0.0083 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER24840.1 - 0.013 15.3 0.0 0.095 12.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EER24840.1 - 0.017 14.7 0.0 0.34 10.5 0.0 2.3 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 EER24840.1 - 0.018 15.2 0.1 0.13 12.4 0.0 2.5 4 0 0 4 4 2 0 RNA helicase NACHT PF05729.7 EER24840.1 - 0.024 14.3 0.0 0.064 12.9 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_32 PF13654.1 EER24840.1 - 0.042 12.5 0.0 0.062 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EER24840.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.10 EER24840.1 - 0.12 12.1 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 EER24840.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Nup54 PF13874.1 EER24841.1 - 2.7e-44 150.2 0.7 2.7e-44 150.2 0.5 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EER24841.1 - 9.7e-07 29.0 90.7 8.9e-06 25.9 33.7 3.1 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF342 PF03961.8 EER24841.1 - 2.4 6.4 6.0 1.3 7.3 2.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Med26 PF08711.6 EER24842.1 - 5e-13 48.3 0.0 9.2e-13 47.4 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Abhydrolase_1 PF00561.15 EER24842.1 - 0.079 12.4 0.0 0.2 11.1 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 EER24843.1 - 2.3e-33 115.4 29.6 2.8e-33 115.0 20.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 EER24843.1 - 0.39 10.7 9.5 0.17 11.9 0.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EER24844.1 - 5.9e-38 130.4 78.8 3.4e-32 111.5 33.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER24844.1 - 2e-07 29.9 15.1 2e-07 29.9 10.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EER24844.1 - 6.2e-05 21.5 10.0 6.2e-05 21.5 6.9 3.1 1 1 2 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 EER24844.1 - 0.063 13.0 9.3 1 9.2 0.1 3.8 4 0 0 4 4 4 0 MFS_1 like family DIM1 PF02966.11 EER24845.1 - 8.4e-71 235.6 0.2 9.5e-71 235.5 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EER24845.1 - 0.0062 16.2 0.1 0.0076 15.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EER24845.1 - 0.0096 16.0 0.9 0.016 15.2 0.6 1.4 1 1 0 1 1 1 1 Thioredoxin-like DUF791 PF05631.9 EER24846.1 - 0.17 10.5 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF791) Peptidase_M19 PF01244.16 EER24847.1 - 8e-111 370.0 0.0 9.9e-111 369.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) 4HBT_2 PF13279.1 EER24848.1 - 3e-11 43.8 0.0 4.9e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily HIG_1_N PF04588.8 EER24849.1 - 2.5e-08 33.5 0.5 4.7e-08 32.6 0.3 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1847 PF08901.6 EER24849.1 - 0.082 12.4 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) RHD3 PF05879.7 EER24850.1 - 0 1036.0 0.1 0 1035.8 0.1 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EER24850.1 - 1.8e-07 30.4 0.1 3.4e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EER24850.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EER24850.1 - 0.00044 20.1 0.0 0.00095 19.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER24850.1 - 0.0016 18.9 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EER24850.1 - 0.0018 18.2 0.0 0.0063 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zn_clus PF00172.13 EER24851.1 - 4.6e-05 23.2 10.3 0.0001 22.0 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EER24851.1 - 0.021 13.6 0.1 0.04 12.7 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.11 EER24852.1 - 9.6e-45 152.8 46.4 9.6e-45 152.8 32.1 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER24852.1 - 3.2e-13 48.7 23.9 4.9e-13 48.1 16.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ABM PF03992.11 EER24853.1 - 6.3e-05 22.9 3.6 0.016 15.2 0.9 3.1 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase MBOAT_2 PF13813.1 EER24855.1 - 4.2e-21 74.7 6.6 1.4e-20 73.1 4.6 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Peptidase_S24 PF00717.18 EER24856.1 - 6.8e-07 28.8 0.0 1.2e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like Rab5ip PF07019.7 EER24857.1 - 0.076 13.1 1.3 0.16 12.0 0.9 1.6 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF3487 PF11990.3 EER24857.1 - 0.16 11.3 0.2 0.24 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) IncA PF04156.9 EER24857.1 - 0.21 11.1 5.3 0.31 10.6 3.7 1.3 1 0 0 1 1 1 0 IncA protein TraT PF05818.7 EER24857.1 - 4.3 6.7 7.2 5.7 6.3 5.0 1.1 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein GTP_EFTU PF00009.22 EER24858.1 - 6e-61 205.1 0.1 8.1e-61 204.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EER24858.1 - 7.5e-24 83.7 0.0 2.1e-23 82.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EER24858.1 - 1.4e-17 63.5 1.3 3.4e-17 62.3 0.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EER24858.1 - 8.2e-06 25.7 0.0 1.5e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EER24858.1 - 0.0005 19.6 0.3 0.0014 18.2 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EER24858.1 - 0.0027 18.1 0.0 0.0048 17.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EER24858.1 - 0.014 14.8 0.3 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.7 EER24858.1 - 0.058 12.5 0.2 0.21 10.6 0.1 1.8 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region cobW PF02492.14 EER24858.1 - 0.058 12.8 0.6 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.13 EER24858.1 - 0.26 10.5 1.6 7.5 5.8 0.2 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B IF3_C PF00707.17 EER24859.1 - 3e-14 52.5 1.0 4.6e-14 51.9 0.7 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EER24859.1 - 4e-06 26.3 1.0 5.5e-06 25.8 0.4 1.4 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.11 EER24859.1 - 0.0013 18.6 0.0 0.0044 16.9 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain FACT-Spt16_Nlob PF14826.1 EER24859.1 - 0.019 14.4 0.8 0.029 13.9 0.5 1.3 1 0 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain GDA1_CD39 PF01150.12 EER24860.1 - 3.4e-99 332.3 0.0 4.1e-99 332.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4598 PF15370.1 EER24861.1 - 3e-13 50.0 0.8 3e-13 50.0 0.6 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Macoilin PF09726.4 EER24861.1 - 0.098 10.9 7.8 0.11 10.7 5.4 1.1 1 0 0 1 1 1 0 Transmembrane protein IF4E PF01652.13 EER24862.1 - 2e-34 118.5 0.2 2.7e-34 118.1 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E COMPASS-Shg1 PF05205.7 EER24863.1 - 8e-30 103.2 0.1 2.3e-29 101.8 0.1 1.8 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Cation_efflux PF01545.16 EER24866.1 - 2.5e-32 112.0 8.2 3.5e-32 111.6 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family zf-RING_2 PF13639.1 EER24867.1 - 1.4e-10 40.7 5.9 3.2e-09 36.4 1.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EER24867.1 - 8.8e-09 35.3 0.5 1.7e-08 34.4 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EER24867.1 - 2.1e-07 30.5 2.7 7.1e-07 28.8 1.9 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EER24867.1 - 2.7e-07 30.1 2.5 6.9e-07 28.8 0.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER24867.1 - 2.7e-06 26.9 1.1 5.2e-06 26.0 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER24867.1 - 4e-06 26.7 6.7 7.3e-06 25.9 1.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EER24867.1 - 0.0053 16.5 1.2 0.013 15.3 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 EER24867.1 - 0.022 12.4 0.5 0.034 11.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) RINGv PF12906.2 EER24867.1 - 3 7.9 6.2 0.48 10.5 1.3 1.9 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 EER24867.1 - 4.5 7.2 6.6 21 5.1 4.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4229 PF14012.1 EER24868.1 - 0.033 14.0 0.4 0.053 13.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Herpes_gE PF02480.11 EER24868.1 - 0.084 11.1 0.1 0.1 10.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 EER24868.1 - 0.13 10.8 0.1 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Pex14_N PF04695.8 EER24869.1 - 0.096 12.7 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.4 EER24869.1 - 4.7 6.9 5.7 46 3.6 0.1 3.2 3 1 1 4 4 4 0 Anti-sigma-K factor rskA GCV_H PF01597.14 EER24870.1 - 4e-42 142.7 2.8 4.9e-42 142.4 1.9 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EER24870.1 - 0.0064 16.1 0.2 0.0087 15.7 0.2 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EER24870.1 - 0.017 14.7 0.7 0.036 13.7 0.3 1.6 2 0 0 2 2 2 0 Biotin-requiring enzyme Ribosomal_S6 PF01250.12 EER24871.1 - 6.7e-10 38.6 0.0 9.3e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Dynamin_N PF00350.18 EER24872.1 - 2e-42 144.8 0.0 3.5e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EER24872.1 - 5e-09 35.3 0.0 4.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EER24872.1 - 0.0026 17.7 0.0 0.0091 15.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER24872.1 - 0.0041 17.6 0.0 0.0093 16.4 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein SRI PF08236.6 EER24872.1 - 0.0084 16.0 0.6 0.026 14.4 0.4 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AAA_16 PF13191.1 EER24872.1 - 0.046 13.7 0.0 0.35 10.8 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 EER24872.1 - 0.11 12.4 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain PARP_reg PF02877.9 EER24872.1 - 0.14 11.7 0.2 10 5.7 0.0 3.3 3 0 0 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain GATase_4 PF13230.1 EER24873.1 - 5.1e-16 58.1 0.1 5e-14 51.6 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EER24873.1 - 1.5e-09 37.9 0.0 2.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EER24873.1 - 2.6e-06 26.4 0.0 0.00033 19.4 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II PAT1 PF09770.4 EER24874.1 - 1.3 7.1 8.6 1.7 6.8 6.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIG-Y PF15159.1 EER24874.1 - 1.4 9.2 10.0 8.5 6.6 6.9 2.1 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF4470 PF14737.1 EER24875.1 - 9.5e-26 89.4 0.0 1.6e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EER24875.1 - 1.3e-09 37.8 11.2 2.3e-09 36.9 7.8 1.4 1 0 0 1 1 1 1 MYND finger tRNA-synt_His PF13393.1 EER24875.1 - 0.24 10.4 0.0 0.39 9.7 0.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase RRM_1 PF00076.17 EER24876.1 - 5.1e-61 202.2 0.0 3.5e-21 74.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER24876.1 - 4.6e-45 151.4 0.0 5.8e-15 55.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER24876.1 - 1.4e-30 104.8 0.0 1.9e-10 40.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER24876.1 - 5.4e-06 26.0 0.0 0.042 13.6 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EER24876.1 - 0.0029 17.5 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 EER24876.1 - 0.048 13.5 0.0 4.2 7.2 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif Limkain-b1 PF11608.3 EER24876.1 - 0.15 11.8 0.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 Arrestin_C PF02752.17 EER24878.1 - 2.2e-12 47.2 0.0 4.8e-10 39.6 0.0 3.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EER24878.1 - 8.5e-10 38.6 0.0 1.6e-05 24.7 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain CFEM PF05730.6 EER24879.1 - 0.00013 21.6 7.1 0.00023 20.9 4.9 1.4 1 0 0 1 1 1 1 CFEM domain NTR2 PF15458.1 EER24879.1 - 0.00027 20.2 0.1 0.00048 19.4 0.1 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF4448 PF14610.1 EER24879.1 - 0.0053 16.2 0.0 0.0088 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1469 PF07332.6 EER24879.1 - 0.024 14.3 1.0 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) SKG6 PF08693.5 EER24879.1 - 0.2 10.9 1.8 0.61 9.4 0.0 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Acetyltransf_1 PF00583.19 EER24882.1 - 1.7e-08 34.3 0.0 2.8e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER24882.1 - 1.8e-06 28.0 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER24882.1 - 0.00043 20.1 0.0 0.48 10.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER24882.1 - 0.0009 19.3 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER24882.1 - 0.00091 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EER24882.1 - 0.036 13.8 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Herpes_gE PF02480.11 EER24883.1 - 0.038 12.2 0.1 0.059 11.6 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PRRSV_2b PF07069.6 EER24883.1 - 0.2 11.9 0.5 0.36 11.1 0.4 1.3 1 0 0 1 1 1 0 Porcine reproductive and respiratory syndrome virus 2b CAP59_mtransfer PF11735.3 EER24884.1 - 3.4e-74 249.1 0.0 4.6e-74 248.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Chs3p PF12271.3 EER24885.1 - 3.9e-144 479.0 20.8 4.5e-144 478.8 14.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit FWWh PF14922.1 EER24885.1 - 0.17 11.3 1.3 0.29 10.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF308 PF03729.8 EER24885.1 - 8.3 6.4 15.9 8.6 6.4 7.9 3.1 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) Abhydrolase_5 PF12695.2 EER24886.1 - 1.1e-07 31.7 0.4 5.4e-07 29.4 0.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER24886.1 - 2.3e-07 30.9 5.1 4.9e-07 29.8 3.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EER24886.1 - 4.2e-07 29.4 0.0 8.1e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EER24886.1 - 0.00016 21.3 0.0 0.00028 20.5 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EER24886.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EER24886.1 - 0.19 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Cyclin PF08613.6 EER24887.1 - 2e-15 57.5 0.0 3.4e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin 4HBT_3 PF13622.1 EER24888.1 - 3.1e-52 177.8 0.7 3.1e-52 177.8 0.5 1.5 1 1 1 2 2 2 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EER24888.1 - 1.5e-06 27.8 0.3 0.012 15.2 0.0 3.4 2 1 1 3 3 3 3 Acyl-CoA thioesterase WD40 PF00400.27 EER24888.1 - 0.1 12.5 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat Ribosomal_L18e PF00828.14 EER24889.1 - 1.9e-16 60.6 0.5 3.3e-16 59.8 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 HNH_2 PF13391.1 EER24890.1 - 1.1e-14 53.9 0.1 2e-14 53.0 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease ERAP1_C PF11838.3 EER24891.1 - 0.00071 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain zf-CCHC PF00098.18 EER24892.1 - 0.00028 20.6 4.6 0.00053 19.7 3.2 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF2603 PF10788.4 EER24892.1 - 0.0042 16.8 3.1 0.0042 16.8 2.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2603) DUF2996 PF11210.3 EER24892.1 - 0.012 15.8 0.1 0.027 14.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2996) Peptidase_M10 PF00413.19 EER24892.1 - 0.047 13.4 0.7 0.62 9.7 0.1 2.3 2 0 0 2 2 2 0 Matrixin CVNH PF08881.5 EER24893.1 - 2.5e-12 46.9 0.0 3e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Pyr_redox_2 PF07992.9 EER24894.1 - 7.6e-27 94.4 0.0 7.7e-16 58.5 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER24894.1 - 9.3e-13 48.3 0.0 6e-11 42.5 0.0 3.0 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER24894.1 - 0.00086 19.4 2.5 1.5 8.8 0.1 3.7 4 1 1 5 5 5 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EER24894.1 - 2.4 8.4 4.4 14 6.0 0.0 3.5 3 2 0 3 3 3 0 Putative NAD(P)-binding Pkinase PF00069.20 EER24895.1 - 2e-49 168.1 0.0 2.6e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24895.1 - 2.1e-27 95.8 0.0 1.5e-21 76.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase SH3_1 PF00018.23 EER24896.1 - 2e-06 27.0 0.0 5.7e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EER24896.1 - 0.0022 17.5 0.0 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PQ-loop PF04193.9 EER24897.1 - 2.2e-37 126.4 11.5 1.8e-19 69.0 0.6 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EER24897.1 - 0.036 13.9 0.2 0.036 13.9 0.1 2.6 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange Sporozoite_P67 PF05642.6 EER24897.1 - 1.2 6.8 3.9 1.6 6.4 2.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Kdo PF06293.9 EER24898.1 - 0.00026 20.0 0.1 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EER24898.1 - 0.00038 20.1 0.4 0.0012 18.4 0.0 2.0 3 0 0 3 3 3 1 Choline/ethanolamine kinase Pkinase PF00069.20 EER24898.1 - 0.00049 19.3 0.0 0.001 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Radial_spoke_3 PF06098.6 EER24898.1 - 0.011 14.7 2.3 0.019 14.0 1.6 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 APH PF01636.18 EER24898.1 - 0.032 13.9 0.0 0.032 13.9 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EER24898.1 - 0.059 12.4 0.1 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase HSDR_N_2 PF13588.1 EER24898.1 - 0.11 12.3 0.0 3.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) Aminotran_1_2 PF00155.16 EER24899.1 - 1.4e-62 211.7 0.0 2e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EER24899.1 - 0.00083 18.5 0.0 0.0021 17.2 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Tmemb_18A PF09771.4 EER24899.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 AMP-binding PF00501.23 EER24900.1 - 2.8e-38 131.4 0.0 3.9e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER24900.1 - 0.00059 20.7 0.0 0.0022 18.9 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.16 EER24901.1 - 3.9e-45 153.7 0.0 8.4e-45 152.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EER24901.1 - 3.2e-40 137.2 0.0 3.5e-39 133.9 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Abhydrolase_2 PF02230.11 EER24902.1 - 2.3e-28 99.0 0.0 1.9e-21 76.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EER24902.1 - 4.3e-09 36.5 0.9 1.5e-08 34.8 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER24902.1 - 6.9e-05 22.6 0.0 0.0002 21.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EER24902.1 - 0.0032 16.9 0.0 0.0065 15.9 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EER24902.1 - 0.011 14.9 0.2 0.047 12.9 0.0 2.0 3 0 0 3 3 3 0 Prolyl oligopeptidase family Tom22 PF04281.8 EER24903.1 - 7.9e-55 184.1 1.0 9.1e-55 183.9 0.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.1 EER24904.1 - 1e-46 158.1 0.0 3.6e-46 156.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF4449 PF14613.1 EER24905.1 - 2.5e-69 232.4 2.6 2.5e-69 232.4 1.8 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) PTPLA PF04387.9 EER24906.1 - 6.4e-53 178.5 2.0 6.4e-53 178.5 1.4 1.7 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Adaptin_binding PF10199.4 EER24907.1 - 3.1e-14 53.4 1.9 1.3e-13 51.4 1.3 2.1 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 LSM PF01423.17 EER24908.1 - 4.1e-14 51.8 0.4 5.6e-14 51.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EER24908.1 - 0.033 14.1 0.1 0.059 13.2 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Tail_tube PF10618.4 EER24908.1 - 0.065 12.9 0.0 0.089 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage tail tube protein PGP_phosphatase PF09419.5 EER24909.1 - 3.3e-45 153.4 0.0 4e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EER24909.1 - 7.2e-08 32.0 0.0 1.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Homeobox PF00046.24 EER24910.1 - 3.6e-20 71.3 3.0 9.3e-20 70.0 2.1 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EER24910.1 - 0.00012 21.7 0.5 0.00032 20.3 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Hydrolase PF00702.21 EER24911.1 - 3e-18 67.0 0.0 3.4e-14 53.7 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EER24911.1 - 9.1e-18 64.1 0.0 3.4e-17 62.2 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EER24911.1 - 1.9e-14 54.2 0.0 1.8e-13 51.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER24911.1 - 3.1e-12 46.2 0.0 3.5e-11 42.9 0.0 2.6 2 1 1 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EER24911.1 - 0.00029 20.5 0.3 0.00097 18.7 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EER24911.1 - 0.071 13.3 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SART-1 PF03343.8 EER24912.1 - 6.2e-176 586.3 64.2 7e-176 586.1 44.5 1.0 1 0 0 1 1 1 1 SART-1 family SIMPL PF04402.9 EER24912.1 - 2.8e-05 24.0 4.8 0.0001 22.2 3.3 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) PTH2 PF01981.11 EER24913.1 - 2.3e-42 143.3 0.0 3.4e-42 142.7 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF2448 PF10476.4 EER24914.1 - 0.082 12.4 0.2 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2448) Cation_efflux PF01545.16 EER24915.1 - 5.2e-39 134.0 4.0 6.1e-39 133.7 2.8 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EER24916.1 - 1.8e-45 155.3 0.3 2.5e-45 154.8 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter HMGL-like PF00682.14 EER24917.1 - 3.4e-71 239.6 0.4 4.9e-71 239.1 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Hpt PF01627.18 EER24918.1 - 1.5e-12 47.3 0.0 2.5e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Zn_clus PF00172.13 EER24919.1 - 4.9e-08 32.7 10.7 4.9e-08 32.7 7.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EER24920.1 - 2.6e-53 181.2 0.0 3.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 EER24921.1 - 4.3e-40 137.1 0.5 8.9e-40 136.1 0.0 1.8 2 1 0 2 2 2 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EER24921.1 - 5e-14 52.1 0.9 2.3e-11 43.4 0.2 2.4 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain DUF3425 PF11905.3 EER24922.1 - 3.7e-35 120.7 0.3 6.6e-35 119.9 0.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EER24922.1 - 0.78 9.7 8.8 1.6 8.7 6.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor ABC2_membrane PF01061.19 EER24923.1 - 9e-93 309.2 51.2 2.3e-48 164.1 16.3 3.2 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EER24923.1 - 2.1e-39 133.3 1.6 3.3e-36 123.0 0.0 3.3 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.22 EER24923.1 - 1.1e-36 126.1 0.0 9.2e-17 61.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EER24923.1 - 8.1e-22 77.1 0.1 1.9e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EER24923.1 - 5.7e-07 29.1 0.1 0.0015 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EER24923.1 - 1.7e-05 24.0 53.6 8e-05 21.8 12.7 3.3 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_33 PF13671.1 EER24923.1 - 1.8e-05 24.6 0.6 0.0094 15.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EER24923.1 - 7.1e-05 22.0 0.1 0.004 16.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EER24923.1 - 0.00028 20.3 1.6 0.024 14.1 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 EER24923.1 - 0.00036 19.8 0.0 0.19 10.9 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EER24923.1 - 0.00041 20.3 3.5 0.0025 17.8 0.1 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_21 PF13304.1 EER24923.1 - 0.00058 19.9 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EER24923.1 - 0.00069 19.1 0.4 0.011 15.2 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EER24923.1 - 0.0014 18.8 0.2 0.1 12.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER24923.1 - 0.0017 19.1 0.0 0.32 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EER24923.1 - 0.0056 16.8 0.8 1.1 9.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EER24923.1 - 0.02 14.6 1.4 5 6.9 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EER24923.1 - 0.025 14.7 0.9 4.1 7.6 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EER24923.1 - 0.036 14.5 0.0 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EER24923.1 - 0.16 11.6 3.1 5 6.7 0.4 2.9 3 0 0 3 3 2 0 NACHT domain AAA_10 PF12846.2 EER24923.1 - 0.24 10.7 1.1 6.3 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EER24923.1 - 0.33 11.2 0.2 2.4 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 EER24924.1 - 2.6e-06 27.4 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER24924.1 - 0.00067 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF4448 PF14610.1 EER24925.1 - 1.4e-42 145.3 0.0 2e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) HAD_2 PF13419.1 EER24927.1 - 4.3e-13 49.8 0.0 4e-12 46.6 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EER24927.1 - 2.3e-11 44.5 0.0 1.5e-08 35.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER24927.1 - 3.5e-08 33.0 0.1 8.4e-08 31.8 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EER24927.1 - 3.2e-05 24.1 0.0 5.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EER24927.1 - 0.0016 17.8 0.0 0.15 11.3 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial PGP phosphatase DUF1177 PF06675.6 EER24927.1 - 0.11 11.0 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) zf-C4_ClpX PF06689.8 EER24928.1 - 1.3 8.6 6.4 13 5.3 1.1 2.6 2 0 0 2 2 2 0 ClpX C4-type zinc finger zf-CCHC_6 PF15288.1 EER24928.1 - 2 8.1 14.8 3.2 7.5 0.3 3.4 1 1 2 3 3 3 0 Zinc knuckle ORMDL PF04061.9 EER24929.1 - 2.2e-61 205.3 4.8 2.6e-61 205.1 3.3 1.0 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EER24929.1 - 0.3 10.7 5.1 0.21 11.2 0.9 1.9 1 1 1 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) CH PF00307.26 EER24931.1 - 2.9e-11 43.3 0.0 4.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Peptidase_S8 PF00082.17 EER24932.1 - 8.9e-45 153.0 10.5 1.4e-44 152.3 7.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER24932.1 - 1e-17 64.4 0.0 1.8e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF3553 PF12073.3 EER24932.1 - 0.048 12.9 0.1 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) Med1 PF10744.4 EER24933.1 - 8.9e-89 297.9 0.0 1.5e-88 297.2 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 p450 PF00067.17 EER24934.1 - 2.2e-101 339.6 0.0 2.6e-101 339.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF159 PF02586.9 EER24935.1 - 3.3e-60 203.1 0.0 4.5e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 DUF1764 PF08576.5 EER24935.1 - 0.025 15.3 2.4 0.059 14.1 1.6 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TPR_12 PF13424.1 EER24936.1 - 4.7e-11 42.4 7.0 3.9e-05 23.5 0.1 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER24936.1 - 5e-06 25.9 6.4 0.016 14.9 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EER24936.1 - 7.5e-05 22.3 10.3 0.00013 21.6 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EER24936.1 - 0.00016 21.2 5.4 0.19 11.3 0.0 3.5 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EER24936.1 - 0.00031 20.2 5.4 0.0039 16.7 0.2 4.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.1 EER24936.1 - 0.0051 16.6 3.4 2.8 8.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER24936.1 - 0.015 15.9 5.3 1.5 9.5 0.0 4.0 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EER24936.1 - 0.047 14.3 3.6 44 5.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EER24936.1 - 0.066 13.6 2.4 0.49 10.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat AnfO_nitrog PF09582.5 EER24936.1 - 0.1 11.6 0.1 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) TPR_7 PF13176.1 EER24936.1 - 0.25 11.2 7.5 36 4.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 EER24937.1 - 2e-59 195.4 26.3 2.8e-12 45.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EER24937.1 - 4.4e-05 21.8 7.2 0.32 9.0 0.1 4.0 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EER24937.1 - 0.0097 14.2 0.0 0.6 8.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Sdh5 PF03937.11 EER24938.1 - 7.2e-24 83.2 0.1 1.6e-23 82.1 0.0 1.6 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase EMP24_GP25L PF01105.19 EER24939.1 - 1.2e-41 142.3 0.0 1.4e-41 142.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RE_SacI PF09566.5 EER24939.1 - 0.11 11.3 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 SacI restriction endonuclease BTB PF00651.26 EER24940.1 - 0.0025 17.7 0.0 0.0046 16.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BSP_II PF05432.6 EER24941.1 - 0.033 13.4 4.1 0.076 12.2 2.9 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 EER24941.1 - 7.6 7.0 10.3 0.16 12.3 1.4 2.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein NDUFA12 PF05071.11 EER24944.1 - 4.8e-14 52.6 1.1 4.8e-14 52.6 0.8 2.0 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Gln-synt_C PF00120.19 EER24946.1 - 1.5e-59 201.2 0.0 1.8e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EER24946.1 - 1.8e-21 75.5 0.0 2.7e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.11 EER24947.1 - 2.3e-37 128.5 45.6 8.7e-32 110.1 18.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EER24947.1 - 0.0022 17.5 2.2 0.0044 16.5 1.6 1.5 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 DAO PF01266.19 EER24948.1 - 2.4e-25 89.2 0.1 3.1e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EER24948.1 - 0.00065 20.0 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER24948.1 - 0.002 18.1 0.1 0.0049 16.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER24948.1 - 0.033 14.0 0.1 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EER24948.1 - 0.036 13.4 0.3 0.068 12.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 EER24948.1 - 0.038 13.1 0.2 0.038 13.1 0.1 1.8 3 0 0 3 3 3 0 Thi4 family NAD_binding_7 PF13241.1 EER24948.1 - 0.085 13.1 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EER24948.1 - 0.2 10.2 0.3 0.47 9.0 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase OTU PF02338.14 EER24949.1 - 1.8e-18 67.2 0.1 6.8e-18 65.4 0.1 1.9 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 EER24949.1 - 0.00019 20.8 0.0 0.00037 19.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain PBP1_TM PF14812.1 EER24949.1 - 8.8 6.7 11.4 1.2 9.5 1.9 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Thioredoxin PF00085.15 EER24950.1 - 1.1e-28 98.9 0.3 1.2e-28 98.8 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EER24950.1 - 9.3e-10 38.7 0.6 6.5e-09 35.9 0.4 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EER24950.1 - 5.9e-08 32.7 0.1 4.6e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EER24950.1 - 4.1e-07 29.6 0.1 4.6e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EER24950.1 - 1.3e-05 24.7 0.8 8.9e-05 22.0 0.6 1.9 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EER24950.1 - 0.00044 20.2 0.3 0.00086 19.2 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EER24950.1 - 0.00054 19.6 0.2 0.00087 18.9 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 EER24950.1 - 0.0046 16.4 0.0 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.6 EER24950.1 - 0.035 13.9 0.0 0.071 13.0 0.0 1.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Thioredoxin_5 PF13743.1 EER24950.1 - 0.043 13.3 0.0 0.084 12.4 0.0 1.6 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.19 EER24950.1 - 0.043 13.8 0.3 0.078 12.9 0.2 1.5 1 1 0 1 1 1 0 Glutaredoxin Fer4_15 PF13459.1 EER24950.1 - 0.068 13.7 0.3 0.39 11.3 0.2 2.1 1 1 0 1 1 1 0 4Fe-4S single cluster domain Peptidase_M19 PF01244.16 EER24951.1 - 2.8e-106 355.0 0.0 3.4e-106 354.7 0.0 1.1 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Toxin_16 PF07945.6 EER24952.1 - 0.072 12.7 4.8 0.18 11.4 3.4 1.6 1 0 0 1 1 1 0 Janus-atracotoxin AA_permease PF00324.16 EER24954.1 - 6.8e-128 427.0 52.1 8.2e-128 426.7 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER24954.1 - 1.5e-26 92.8 58.2 1.9e-26 92.5 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M50 PF02163.17 EER24954.1 - 1.1 8.1 6.1 1.9 7.4 0.6 3.1 1 1 1 2 2 2 0 Peptidase family M50 DUF1681 PF07933.9 EER24955.1 - 1.6e-53 180.5 0.0 3e-53 179.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) IF-2B PF01008.12 EER24956.1 - 1.4e-45 155.4 0.0 3.5e-45 154.1 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family Nuf2 PF03800.9 EER24957.1 - 1.4e-43 148.3 0.0 1.4e-43 148.3 0.0 2.4 3 0 0 3 3 3 1 Nuf2 family Reo_sigmaC PF04582.7 EER24957.1 - 0.027 13.6 7.1 0.5 9.5 1.3 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Clr5 PF14420.1 EER24957.1 - 0.3 10.9 4.6 7.2 6.5 0.3 2.9 3 0 0 3 3 3 0 Clr5 domain DUF3782 PF12644.2 EER24957.1 - 0.36 10.6 0.0 0.36 10.6 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) Adaptin_N PF01602.15 EER24958.1 - 8.6e-106 354.3 0.2 1e-105 354.0 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EER24958.1 - 5.1e-12 45.9 2.2 0.00015 21.9 0.0 4.7 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EER24958.1 - 1.9e-07 30.6 0.1 0.14 12.2 0.0 5.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EER24958.1 - 0.0044 17.4 2.0 22 5.7 0.0 5.1 5 0 0 5 5 5 0 HEAT-like repeat Cohesin_HEAT PF12765.2 EER24958.1 - 0.005 16.7 0.1 1 9.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EER24958.1 - 0.0061 16.4 1.1 5.9 6.6 0.0 3.5 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 VHS PF00790.14 EER24958.1 - 0.007 15.9 0.3 27 4.3 0.0 4.5 4 0 0 4 4 4 0 VHS domain MOR2-PAG1_N PF14222.1 EER24958.1 - 0.018 13.7 0.1 0.039 12.6 0.0 1.5 1 0 0 1 1 1 0 Cell morphogenesis N-terminal SDA1 PF05285.7 EER24958.1 - 0.13 11.5 29.4 0.046 13.0 17.4 2.1 2 0 0 2 2 2 0 SDA1 Metallophos PF00149.23 EER24961.1 - 1e-42 145.8 0.6 1.4e-42 145.4 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 EER24962.1 - 1.5e-60 204.0 0.2 1.6e-60 203.9 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor KilA-N PF04383.8 EER24963.1 - 0.00068 19.2 0.0 0.0079 15.8 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Clp1 PF06807.9 EER24964.1 - 4.2e-13 49.4 0.0 2.2e-08 34.1 0.0 3.1 2 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EER24964.1 - 2.3e-06 27.3 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EER24964.1 - 6.3e-05 22.6 0.0 0.00022 20.8 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EER24964.1 - 0.00088 19.2 0.0 0.0043 16.9 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EER24964.1 - 0.054 13.4 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EER24964.1 - 0.065 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EER24964.1 - 0.092 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.1 EER24964.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain ADH_zinc_N PF00107.21 EER24966.1 - 1.3e-29 102.3 0.0 2.2e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER24966.1 - 6.7e-20 72.2 0.0 1.3e-19 71.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER24966.1 - 2.1e-10 40.2 0.0 9.9e-10 38.1 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Arb1 PF09692.5 EER24967.1 - 5.3e-143 476.6 0.0 6.7e-143 476.2 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 EER24968.1 - 3.5e-57 193.2 0.0 5.2e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Ribosomal_S19 PF00203.16 EER24969.1 - 6.5e-22 76.9 0.0 7.6e-22 76.7 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein S19 TFIID_30kDa PF03540.8 EER24970.1 - 1.3e-23 82.5 0.1 2.1e-23 81.8 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Mitofilin PF09731.4 EER24970.1 - 3.8 6.0 10.3 4.5 5.7 7.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TRF PF08558.5 EER24971.1 - 3.4e-80 268.8 0.0 6e-80 268.0 0.0 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EER24971.1 - 1.6e-05 24.8 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4037 PF13228.1 EER24971.1 - 0.079 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) His_Phos_2 PF00328.17 EER24972.1 - 1.2e-11 44.6 0.0 5.1e-11 42.4 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Shisa PF13908.1 EER24972.1 - 0.027 14.6 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.11 EER24974.1 - 1.8e-33 115.6 51.4 2.8e-31 108.5 37.7 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4006 PF13179.1 EER24974.1 - 0.11 11.9 0.0 0.5 9.9 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Pkinase PF00069.20 EER24975.1 - 6.2e-71 238.5 0.0 1.3e-70 237.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER24975.1 - 4.1e-30 104.7 0.0 7.6e-29 100.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER24975.1 - 9.2e-06 24.8 0.0 0.41 9.5 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Kdo PF06293.9 EER24975.1 - 0.041 12.9 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER24975.1 - 0.13 12.0 0.0 5.4 6.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S5_C PF03719.10 EER24976.1 - 3.3e-21 74.3 0.0 3.2e-20 71.1 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EER24976.1 - 1.3e-06 28.0 1.7 3.4e-06 26.6 0.1 2.2 1 1 1 2 2 2 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.6 EER24977.1 - 6.9e-16 57.8 0.0 5.2e-14 51.6 0.0 2.5 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EER24977.1 - 1.1e-07 31.5 0.0 2.8e-07 30.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EER24977.1 - 0.0001 21.5 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRAM PF01938.15 EER24977.1 - 0.00018 21.1 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 TRAM domain Methyltransf_26 PF13659.1 EER24977.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER24977.1 - 0.0015 19.1 0.0 0.0031 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EER24977.1 - 0.0027 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.12 EER24977.1 - 0.01 14.8 0.0 0.065 12.2 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 EER24977.1 - 0.011 15.1 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EER24977.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltrans_SAM PF10672.4 EER24977.1 - 0.025 13.4 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Actin PF00022.14 EER24978.1 - 8.3e-90 301.0 0.0 1.6e-89 300.1 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EER24978.1 - 0.012 14.2 0.0 0.45 9.0 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 EER24979.1 - 4.1e-35 121.0 5.9 3.2e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 EER24980.1 - 5e-117 390.0 0.0 5.9e-117 389.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 UNC45-central PF11701.3 EER24981.1 - 1.7e-34 118.7 1.5 4.2e-33 114.2 0.1 3.6 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.18 EER24981.1 - 0.0016 18.1 11.5 2.3 8.1 0.0 6.5 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat TPR_11 PF13414.1 EER24981.1 - 0.018 14.6 2.8 0.059 13.0 2.0 1.9 1 0 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 EER24981.1 - 0.64 10.8 4.3 1.4 9.7 0.9 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HSCB_C PF07743.8 EER24981.1 - 0.82 10.1 4.3 4.4 7.8 0.1 2.9 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain GDPD PF03009.12 EER24982.1 - 9.8e-68 228.4 0.0 2.3e-67 227.2 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EER24982.1 - 5.7e-33 113.1 0.5 6.2e-12 45.6 0.4 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER24982.1 - 1e-32 111.8 1.0 7.4e-11 42.2 0.0 5.0 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 EER24982.1 - 4.4e-28 98.8 5.2 2.9e-15 56.8 2.7 3.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 EER24982.1 - 2.9e-25 86.7 4.3 3.3e-05 23.4 0.0 6.9 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EER24982.1 - 5.1e-17 61.5 0.9 9e-06 25.7 0.0 5.6 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER24982.1 - 9.5e-17 59.4 3.7 0.00057 19.8 0.0 7.4 7 0 0 7 7 7 3 Ankyrin repeat PRMT5 PF05185.11 EER24983.1 - 6.7e-170 565.8 0.0 8.5e-170 565.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EER24984.1 - 5.8e-25 87.3 0.0 1.3e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EER24984.1 - 1e-23 83.2 0.1 3.9e-23 81.4 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EER24984.1 - 3.6e-10 39.5 0.0 8.8e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EER24984.1 - 1.2e-06 28.1 0.2 2.6e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EER24984.1 - 5.4e-06 26.5 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.9 EER24984.1 - 0.001 18.8 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain SRP54 PF00448.17 EER24984.1 - 0.0019 17.6 0.1 0.0052 16.2 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EER24984.1 - 0.013 15.2 0.0 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EER24984.1 - 0.015 14.2 0.0 0.031 13.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EER24984.1 - 0.05 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EER24984.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EER24984.1 - 0.17 12.1 0.1 0.63 10.3 0.1 2.1 1 1 0 1 1 1 0 ABC transporter MADF_DNA_bdg PF10545.4 EER24985.1 - 0.062 13.4 2.7 0.85 9.8 1.9 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like EF-hand_6 PF13405.1 EER24986.1 - 2.6e-08 33.0 0.0 0.011 15.5 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EER24986.1 - 0.00037 20.5 0.6 0.0012 18.8 0.1 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EER24986.1 - 0.00083 18.4 0.0 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EER24986.1 - 0.013 14.7 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 EER24986.1 - 0.029 13.9 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Met_10 PF02475.11 EER24987.1 - 5.4e-05 22.8 0.0 9.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Vinculin PF01044.14 EER24987.1 - 0.092 10.7 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Vinculin family Imm46 PF15585.1 EER24987.1 - 0.13 12.2 0.1 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 46 Cons_hypoth95 PF03602.10 EER24987.1 - 0.14 11.5 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 MFS_1 PF07690.11 EER24988.1 - 7.6e-22 77.4 74.1 4.5e-19 68.3 28.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 EER24989.1 - 1.4e-05 24.7 0.6 0.033 14.0 0.0 4.5 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EER24989.1 - 0.00021 20.2 0.0 0.00046 19.1 0.0 1.6 1 0 0 1 1 1 1 Coatomer WD associated region CNH PF00780.17 EER24989.1 - 0.00022 20.7 0.2 0.3 10.4 0.1 3.1 2 1 0 2 2 2 2 CNH domain Hira PF07569.6 EER24989.1 - 0.0022 17.2 0.1 0.17 11.0 0.0 3.0 3 0 0 3 3 3 1 TUP1-like enhancer of split Apc4_WD40 PF12894.2 EER24989.1 - 0.029 13.8 0.0 8.8 5.9 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DNA_gyraseA_C PF03989.8 EER24989.1 - 0.051 12.8 0.1 0.7 9.2 0.0 2.4 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Cupin_8 PF13621.1 EER24990.1 - 3.7e-45 154.4 0.0 5.6e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 EER24990.1 - 8.6e-19 67.8 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 EER24990.1 - 6e-16 57.9 10.8 1.4e-05 24.7 0.1 6.3 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EER24990.1 - 4.2e-09 36.3 6.2 0.0033 17.5 0.0 5.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EER24990.1 - 3e-08 33.4 1.2 0.013 15.4 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Cupin_4 PF08007.7 EER24990.1 - 4.7e-06 26.0 0.0 8.8e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_1 PF01344.20 EER24990.1 - 0.0096 15.4 0.1 1.4 8.5 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 EER24990.1 - 0.056 13.6 10.7 0.18 12.0 0.1 5.1 4 1 2 6 6 6 0 Kelch motif Kelch_2 PF07646.10 EER24990.1 - 0.84 9.5 5.9 23 4.9 0.0 3.9 4 0 0 4 4 4 0 Kelch motif DSPc PF00782.15 EER24991.1 - 1.9e-28 98.6 0.0 5.1e-20 71.4 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EER24991.1 - 0.00012 21.5 0.0 0.0021 17.4 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EER24991.1 - 0.0083 16.1 0.0 0.038 14.0 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DNA_mis_repair PF01119.14 EER24992.1 - 2.1e-35 120.7 0.1 2.9e-34 117.0 0.0 2.5 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EER24992.1 - 1.2e-14 54.1 0.0 7e-14 51.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EER24992.1 - 1e-10 41.2 0.0 2.5e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YabP PF07873.6 EER24993.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 YabP family PC_rep PF01851.17 EER24994.1 - 9.1e-19 66.5 20.2 7.9e-05 22.6 0.1 9.2 10 0 0 10 10 10 5 Proteasome/cyclosome repeat TPR_5 PF12688.2 EER24994.1 - 0.078 13.0 0.8 6.3 6.8 0.0 3.5 3 1 1 4 4 4 0 Tetratrico peptide repeat RIO1 PF01163.17 EER24995.1 - 1.6e-42 145.0 0.7 6.5e-30 103.8 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EER24995.1 - 3.5e-32 110.3 0.0 6.6e-32 109.4 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EER24995.1 - 7.1e-10 39.0 0.0 2.6e-05 24.0 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EER24995.1 - 1.1e-08 34.4 0.1 5.7e-07 28.8 0.0 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.7 EER24995.1 - 6.2 5.9 5.4 9.3 5.4 3.7 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L23 PF00276.15 EER24996.1 - 2.2e-16 59.5 0.0 3.3e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 Lon_C PF05362.8 EER24997.1 - 4e-70 235.3 0.6 1.2e-69 233.7 0.3 1.9 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EER24997.1 - 3.4e-25 88.9 0.2 1.3e-24 87.0 0.0 2.0 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EER24997.1 - 1.1e-23 83.8 0.0 5.4e-23 81.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EER24997.1 - 9.3e-08 31.6 0.1 3.7e-07 29.6 0.0 2.1 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EER24997.1 - 1.9e-07 30.9 0.0 5.8e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EER24997.1 - 1.5e-06 28.2 0.2 5.6e-06 26.4 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.7 EER24997.1 - 1.7e-05 23.9 0.1 0.00026 20.1 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EER24997.1 - 2.4e-05 25.1 0.0 9.3e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EER24997.1 - 0.00013 21.5 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EER24997.1 - 0.00014 21.5 0.1 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EER24997.1 - 0.0004 19.8 0.0 0.00096 18.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EER24997.1 - 0.00051 18.8 0.1 0.0043 15.8 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 EER24997.1 - 0.00054 20.1 0.0 0.0041 17.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain Birna_VP4 PF01768.11 EER24997.1 - 0.00079 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_33 PF13671.1 EER24997.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EER24997.1 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 EER24997.1 - 0.0016 18.3 0.0 0.0043 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EER24997.1 - 0.0034 17.3 0.0 0.01 15.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EER24997.1 - 0.017 15.3 0.0 0.05 13.7 0.0 1.8 2 0 0 2 2 1 0 RNA helicase Mg_chelatase PF01078.16 EER24997.1 - 0.018 14.2 0.2 0.046 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EER24997.1 - 0.019 15.2 0.1 0.06 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EER24997.1 - 0.021 14.2 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EER24997.1 - 0.026 14.0 0.2 0.059 12.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EER24997.1 - 0.028 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EER24997.1 - 0.03 13.9 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_PrkA PF08298.6 EER24997.1 - 0.034 12.8 0.1 0.18 10.4 0.0 1.9 2 0 0 2 2 2 0 PrkA AAA domain ABC_tran PF00005.22 EER24997.1 - 0.041 14.1 1.0 0.24 11.6 0.0 2.6 3 0 0 3 3 2 0 ABC transporter AAA_10 PF12846.2 EER24997.1 - 0.045 13.1 0.1 0.66 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_23 PF13476.1 EER24997.1 - 0.048 13.9 0.0 0.048 13.9 0.0 3.0 2 1 1 3 3 1 0 AAA domain NB-ARC PF00931.17 EER24997.1 - 0.05 12.4 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 EER24997.1 - 0.051 12.8 0.0 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 EER24997.1 - 0.058 13.0 0.0 0.26 10.9 0.0 2.1 1 1 1 2 2 1 0 Archaeal ATPase MobB PF03205.9 EER24997.1 - 0.067 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EER24997.1 - 0.068 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 EER24997.1 - 0.13 11.7 1.5 0.33 10.5 0.0 2.0 1 1 1 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 EER24997.1 - 0.23 10.2 0.0 0.41 9.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CCDC-167 PF15188.1 EER24997.1 - 1 9.3 5.3 2.9 7.9 0.9 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 Porphobil_deam PF01379.15 EER24998.1 - 6e-74 247.5 0.0 7.9e-74 247.1 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EER24998.1 - 1.4e-16 60.3 0.1 2.3e-16 59.6 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain SRP_SPB PF02978.14 EER24998.1 - 0.12 12.6 0.0 1.3 9.3 0.0 2.3 2 1 0 2 2 2 0 Signal peptide binding domain Lipase_GDSL_2 PF13472.1 EER24999.1 - 1.2e-17 64.6 0.0 3.2e-17 63.2 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EER24999.1 - 2.1e-14 53.8 0.0 2.6e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TAP42 PF04177.7 EER25000.1 - 2.4e-108 362.0 2.3 2.7e-108 361.9 1.6 1.0 1 0 0 1 1 1 1 TAP42-like family DUF4404 PF14357.1 EER25000.1 - 4 7.9 7.4 8.8 6.8 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) Ribonuclease_3 PF00636.21 EER25001.1 - 1.1e-44 151.4 0.0 1.1e-21 77.4 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EER25001.1 - 5.1e-28 97.5 0.0 6.9e-15 55.1 0.0 3.6 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EER25001.1 - 1.3e-23 82.6 1.2 3e-22 78.1 0.0 3.2 4 0 0 4 4 4 1 Dicer dimerisation domain Helicase_C PF00271.26 EER25001.1 - 3.8e-14 52.3 0.1 1.1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25001.1 - 1.3e-10 41.4 0.1 3.9e-10 39.8 0.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EER25001.1 - 1.5e-10 40.8 0.1 7e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase dsrm PF00035.20 EER25001.1 - 1.1e-05 25.8 0.2 0.1 13.1 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif SNF2_N PF00176.18 EER25001.1 - 0.00028 19.7 0.1 0.00051 18.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 EER25001.1 - 0.019 13.9 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SDA1 PF05285.7 EER25001.1 - 0.039 13.2 2.4 0.063 12.5 1.7 1.3 1 0 0 1 1 1 0 SDA1 T2SE PF00437.15 EER25001.1 - 0.09 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DHC_N1 PF08385.7 EER25002.1 - 4.2e-186 619.7 5.6 4.2e-186 619.7 3.9 4.6 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EER25002.1 - 2.8e-130 434.5 5.5 2.8e-130 434.5 3.8 4.3 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EER25002.1 - 2.6e-107 359.6 0.0 8.3e-107 357.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EER25002.1 - 7.5e-78 261.2 0.0 2e-77 259.8 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EER25002.1 - 3.3e-44 150.4 0.2 1.6e-43 148.1 0.1 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EER25002.1 - 7.9e-42 143.0 0.2 8.7e-41 139.6 0.1 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EER25002.1 - 4.2e-39 134.2 7.3 8.4e-39 133.2 5.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EER25002.1 - 1e-32 112.7 0.8 1e-10 41.4 0.0 6.6 6 1 0 6 6 6 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EER25002.1 - 2.9e-19 69.1 0.0 1.6e-18 66.7 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 EER25002.1 - 1.7e-14 54.1 0.0 0.00042 20.5 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER25002.1 - 2e-14 53.8 5.7 0.0067 16.5 0.0 6.6 7 0 0 7 7 5 4 AAA domain AAA_17 PF13207.1 EER25002.1 - 3.2e-11 44.1 0.1 0.033 15.0 0.0 6.8 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.1 EER25002.1 - 2.9e-10 40.1 2.9 0.13 12.0 0.0 6.2 6 0 0 6 6 5 3 AAA domain AAA_18 PF13238.1 EER25002.1 - 3.4e-10 40.3 0.2 0.026 14.8 0.0 5.7 5 0 0 5 5 5 2 AAA domain T2SE PF00437.15 EER25002.1 - 1.4e-07 30.6 0.0 0.078 11.8 0.0 4.0 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_14 PF13173.1 EER25002.1 - 1.8e-06 27.8 0.0 0.19 11.6 0.0 5.7 6 0 0 6 6 4 1 AAA domain ABC_tran PF00005.22 EER25002.1 - 2.8e-06 27.6 1.5 0.33 11.2 0.0 5.6 5 0 0 5 5 4 2 ABC transporter AAA_29 PF13555.1 EER25002.1 - 2e-05 23.9 0.1 2 7.9 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EER25002.1 - 6e-05 22.2 0.7 0.5 9.4 0.0 4.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EER25002.1 - 6.6e-05 22.9 19.4 0.11 12.4 0.1 8.6 8 2 1 9 9 9 1 AAA ATPase domain AAA_19 PF13245.1 EER25002.1 - 8e-05 22.3 0.3 0.89 9.3 0.0 4.3 4 0 0 4 4 4 1 Part of AAA domain Zeta_toxin PF06414.7 EER25002.1 - 0.0025 16.9 4.1 0.94 8.5 0.0 4.5 4 0 0 4 4 3 1 Zeta toxin RNA_helicase PF00910.17 EER25002.1 - 0.0026 17.9 0.2 14 5.9 0.0 5.1 5 0 0 5 5 5 0 RNA helicase AAA_25 PF13481.1 EER25002.1 - 0.0041 16.5 0.6 0.41 10.0 0.0 4.0 4 0 0 4 4 4 1 AAA domain MobB PF03205.9 EER25002.1 - 0.0079 15.8 0.6 12 5.5 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EER25002.1 - 0.011 15.2 2.1 7.1 6.1 0.1 4.5 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation ERM PF00769.14 EER25002.1 - 0.19 11.2 28.5 2.5 7.5 13.2 3.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Acetyltransf_7 PF13508.1 EER25003.1 - 5.9e-05 23.1 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER25003.1 - 0.00018 21.5 0.3 0.01 15.9 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER25003.1 - 0.00022 21.1 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pho86 PF11124.3 EER25003.1 - 0.0017 17.4 0.0 0.0023 17.0 0.0 1.1 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Acetyltransf_9 PF13527.1 EER25003.1 - 0.12 12.2 0.1 13 5.6 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Svf1 PF08622.5 EER25005.1 - 2.2e-128 427.8 0.0 2.9e-128 427.4 0.0 1.1 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EER25005.1 - 0.0027 17.0 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Ribosomal_L11_N PF03946.9 EER25006.1 - 5.8e-27 92.9 0.1 1.6e-26 91.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EER25006.1 - 5.4e-23 80.9 0.0 1.2e-22 79.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Pkinase PF00069.20 EER25007.1 - 3.5e-50 170.5 0.0 4.8e-50 170.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25007.1 - 1.6e-20 73.3 0.0 2.4e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER25007.1 - 0.00066 18.7 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER25007.1 - 0.0052 16.5 0.4 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF3337 PF11816.3 EER25008.1 - 1.1e-82 278.1 0.0 5e-78 262.7 0.2 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EER25008.1 - 5e-27 92.7 22.8 8.5e-08 31.7 0.2 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat MFS_1 PF07690.11 EER25009.1 - 6.2e-38 130.4 28.7 6.2e-38 130.4 19.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Syndecan PF01034.15 EER25009.1 - 0.079 12.6 0.1 2 8.1 0.0 3.0 3 0 0 3 3 3 0 Syndecan domain MFS_1_like PF12832.2 EER25009.1 - 0.11 12.3 6.0 0.075 12.8 2.0 2.4 2 0 0 2 2 2 0 MFS_1 like family Mito_carr PF00153.22 EER25010.1 - 8.9e-46 153.5 0.8 5.1e-19 67.7 0.1 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein ATP_bind_3 PF01171.15 EER25011.1 - 5.6e-39 133.5 0.0 7.4e-30 103.7 0.0 2.9 3 0 0 3 3 3 2 PP-loop family NAD_synthase PF02540.12 EER25011.1 - 0.074 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Asn_synthase PF00733.16 EER25011.1 - 0.17 11.3 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase RhoGEF PF00621.15 EER25012.1 - 4.5e-22 78.7 0.0 1e-21 77.6 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 EER25012.1 - 3.6e-05 23.3 0.0 6.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Glyco_trans_1_3 PF13528.1 EER25012.1 - 0.2 10.8 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 CorA PF01544.13 EER25012.1 - 1.3 8.0 4.8 7.8 5.4 0.1 2.8 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Seryl_tRNA_N PF02403.17 EER25012.1 - 5.8 6.9 8.6 16 5.5 1.6 3.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sec7 PF01369.15 EER25014.1 - 2.9e-59 199.9 0.0 4.9e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EER25014.1 - 6.9e-22 77.6 0.0 2.4e-15 56.3 0.1 2.9 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal TAN PF11640.3 EER25014.1 - 0.02 14.6 0.3 5.7 6.6 0.0 3.1 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair TPR_12 PF13424.1 EER25015.1 - 1e-12 47.7 0.1 0.47 10.4 0.0 7.7 6 1 0 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 EER25015.1 - 8.5e-11 42.1 16.4 0.028 14.1 0.1 6.3 5 2 1 6 6 6 5 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EER25015.1 - 6.6e-10 38.7 10.7 2.4 9.0 0.0 11.3 11 3 2 13 13 12 1 Tetratricopeptide repeat TPR_11 PF13414.1 EER25015.1 - 6.3e-07 28.9 3.3 16 5.1 0.1 7.4 7 2 1 8 8 8 0 TPR repeat Mad3_BUB1_I PF08311.7 EER25015.1 - 1.7e-06 27.8 12.3 0.12 12.1 0.1 6.9 5 2 1 6 6 6 1 Mad3/BUB1 homology region 1 TPR_2 PF07719.12 EER25015.1 - 3.3e-06 26.5 10.9 1.6 8.8 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER25015.1 - 0.00027 20.4 3.5 6.1 6.9 0.0 6.6 8 0 0 8 8 8 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EER25015.1 - 0.00053 18.9 6.0 0.05 12.4 1.8 5.1 2 2 2 4 4 4 1 NRDE-2, necessary for RNA interference TPR_8 PF13181.1 EER25015.1 - 0.00082 18.9 3.4 60 3.7 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EER25015.1 - 0.0052 16.8 6.4 5.1 7.5 0.0 7.0 9 0 0 9 9 9 1 Tetratricopeptide repeat HAT PF02184.11 EER25015.1 - 0.066 12.9 7.7 2.4 7.9 0.0 5.8 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat TPR_6 PF13174.1 EER25015.1 - 10 6.8 8.3 1.3e+02 3.3 0.0 6.4 8 0 0 8 8 7 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 EER25016.1 - 1.2e-65 220.7 1.6 1.5e-65 220.4 1.1 1.1 1 0 0 1 1 1 1 ATP synthase subunit D RICH PF05062.7 EER25016.1 - 0.054 13.6 1.3 0.13 12.3 0.3 2.0 2 0 0 2 2 2 0 RICH domain SYCE1 PF15233.1 EER25016.1 - 0.073 12.9 0.6 0.073 12.9 0.4 1.9 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Nup54 PF13874.1 EER25016.1 - 0.28 10.8 2.7 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Viral_P18 PF04521.8 EER25016.1 - 2.1 7.8 4.5 20 4.6 0.6 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein RRM_1 PF00076.17 EER25017.1 - 5.7e-23 80.3 5.6 7e-12 44.8 0.5 2.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER25017.1 - 3.5e-16 58.9 1.3 7.2e-07 29.0 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25017.1 - 4.1e-16 58.5 0.0 2.9e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.1 EER25017.1 - 0.12 11.8 0.0 0.78 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) TFCD_C PF12612.3 EER25018.1 - 3.2e-40 137.6 0.3 1.3e-39 135.6 0.0 2.3 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.1 EER25018.1 - 5.1e-05 23.4 10.4 0.31 11.3 0.2 5.4 6 1 1 7 7 7 2 HEAT repeats HEAT PF02985.17 EER25018.1 - 0.00044 20.0 14.9 1.8 8.8 0.1 7.3 8 0 0 8 8 8 2 HEAT repeat HEAT_PBS PF03130.11 EER25018.1 - 0.051 14.0 2.0 4.4 8.0 0.0 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Arm PF00514.18 EER25018.1 - 2.9 7.8 5.3 4.3 7.3 0.0 4.0 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EER25018.1 - 3.1 8.4 20.1 1 9.9 0.3 7.3 9 1 1 10 10 10 0 HEAT-like repeat Pkinase PF00069.20 EER25020.1 - 3.4e-62 209.9 0.0 5.6e-62 209.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25020.1 - 8.3e-36 123.3 0.0 1.5e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EER25020.1 - 2.4e-33 113.6 16.0 3.6e-19 68.2 2.9 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EER25020.1 - 6.7e-21 73.7 29.5 5.9e-12 45.1 6.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EER25020.1 - 3.6e-13 49.7 3.9 8e-13 48.6 2.7 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EER25020.1 - 0.0057 15.6 0.0 0.0099 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 EER25020.1 - 0.089 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 C2 domain FYVE_2 PF02318.11 EER25020.1 - 3.3 7.6 19.7 2.2 8.2 4.3 2.6 1 1 1 2 2 2 0 FYVE-type zinc finger Uds1 PF15456.1 EER25020.1 - 8.7 6.3 7.5 0.82 9.6 0.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation MFS_1 PF07690.11 EER25021.1 - 4.4e-26 91.4 45.4 1.5e-19 69.9 10.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.1 EER25021.1 - 0.046 13.2 0.1 1.8 8.0 0.0 2.6 2 0 0 2 2 2 0 PgaD-like protein eIF-1a PF01176.14 EER25023.1 - 2.4e-17 62.0 0.0 3.3e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 EER25024.1 - 1.2e-127 426.1 20.6 1.4e-127 425.9 14.3 1.0 1 0 0 1 1 1 1 ALG3 protein Metallophos PF00149.23 EER25026.1 - 1.9e-36 125.3 0.6 1.2e-29 103.1 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Fungal_trans PF04082.13 EER25027.1 - 2.5e-42 144.5 1.5 2.6e-42 144.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER25027.1 - 6.2e-08 32.4 9.0 1.3e-07 31.4 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 EER25027.1 - 0.067 12.8 5.7 0.07 12.8 2.8 1.9 2 0 0 2 2 2 0 PHD-finger bZIP_1 PF00170.16 EER25028.1 - 0.0031 17.4 9.4 0.0031 17.4 6.5 2.2 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EER25028.1 - 0.0082 15.9 12.5 0.0082 15.9 8.7 2.1 3 0 0 3 3 3 1 Basic region leucine zipper UCH PF00443.24 EER25029.1 - 1.6e-35 122.5 0.2 2.6e-35 121.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER25029.1 - 4.2e-08 32.9 0.1 1e-07 31.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AsnC_trans_reg PF01037.16 EER25029.1 - 0.071 12.8 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 AsnC family DNA_ligase_A_M PF01068.16 EER25030.1 - 1.8e-45 154.7 0.0 4.1e-45 153.6 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EER25030.1 - 4.7e-39 134.0 0.0 8.2e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EER25030.1 - 1e-14 54.6 0.0 2.9e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EER25030.1 - 5.7e-11 42.4 0.0 7.1e-07 29.2 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EER25030.1 - 0.0013 18.4 0.0 0.55 10.1 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain EF-hand_4 PF12763.2 EER25031.1 - 2.4e-06 27.2 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Zn_clus PF00172.13 EER25032.1 - 0.00018 21.3 8.6 0.00081 19.2 5.9 2.1 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EER25032.1 - 0.00019 20.3 0.0 0.00035 19.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spb1_C PF07780.7 EER25034.1 - 2.6e-72 242.8 35.7 2.6e-72 242.8 24.7 3.9 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 EER25034.1 - 8.8e-59 197.5 9.3 8.8e-59 197.5 6.4 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EER25034.1 - 5.8e-54 182.8 0.0 1.2e-53 181.7 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase EamA PF00892.15 EER25035.1 - 1.8e-07 31.2 2.1 1.8e-07 31.2 1.4 3.3 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 EER25035.1 - 3.7e-07 29.2 14.5 5.8e-07 28.6 7.2 2.0 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EER25035.1 - 7.3e-07 29.3 1.3 7.3e-07 29.3 0.9 3.7 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 EER25035.1 - 2.8e-05 23.2 8.3 2.8e-05 23.2 5.8 1.5 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 EER25035.1 - 0.0087 15.7 25.8 0.19 11.3 4.8 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family Ras PF00071.17 EER25036.1 - 2.7e-55 186.1 0.1 3.2e-55 185.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER25036.1 - 8.4e-19 68.2 0.0 1.5e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER25036.1 - 1.1e-11 44.2 0.0 1.3e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER25036.1 - 6e-08 32.1 0.0 7.3e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EER25036.1 - 1.9e-07 31.0 0.0 2.5e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER25036.1 - 1.4e-06 27.8 0.0 4.8e-05 22.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EER25036.1 - 0.00025 21.2 0.0 0.00044 20.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EER25036.1 - 0.00088 18.5 0.1 0.0017 17.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EER25036.1 - 0.0029 17.1 0.1 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EER25036.1 - 0.0038 16.4 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EER25036.1 - 0.0052 16.3 0.1 0.01 15.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EER25036.1 - 0.0054 16.4 0.6 0.0086 15.8 0.1 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 EER25036.1 - 0.0056 16.4 0.0 0.016 14.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EER25036.1 - 0.011 15.1 0.1 0.027 13.9 0.1 1.5 1 1 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 EER25036.1 - 0.013 15.0 0.4 0.4 10.1 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 EER25036.1 - 0.014 14.3 0.1 0.038 13.0 0.0 1.7 2 0 0 2 2 2 0 Septin cobW PF02492.14 EER25036.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EER25036.1 - 0.022 14.4 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EER25036.1 - 0.027 14.4 0.0 0.053 13.5 0.0 1.5 2 0 0 2 2 1 0 AAA ATPase domain RNA_helicase PF00910.17 EER25036.1 - 0.076 13.1 0.0 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.1 EER25036.1 - 0.079 12.8 0.1 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EER25036.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EER25036.1 - 0.13 12.5 0.2 0.19 12.0 0.2 1.7 1 1 0 1 1 1 0 ABC transporter ATG16 PF08614.6 EER25037.1 - 4.8e-49 166.8 7.2 5.7e-49 166.5 5.0 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EER25037.1 - 0.032 13.8 10.7 5.7 6.4 7.7 2.4 1 1 0 1 1 1 0 IncA protein ADK PF00406.17 EER25037.1 - 0.054 13.3 5.3 3 7.6 1.0 2.8 2 1 1 3 3 3 0 Adenylate kinase GAS PF13851.1 EER25037.1 - 0.073 12.2 15.8 0.54 9.4 4.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IF2_N PF04760.10 EER25037.1 - 0.089 12.4 0.4 0.22 11.2 0.3 1.6 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region CCDC144C PF14915.1 EER25037.1 - 0.1 11.5 18.6 0.073 11.9 10.4 2.2 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region APG6 PF04111.7 EER25037.1 - 0.13 11.2 7.6 0.079 12.0 4.1 1.4 2 0 0 2 2 2 0 Autophagy protein Apg6 Tropomyosin PF00261.15 EER25037.1 - 0.14 11.2 19.4 0.048 12.7 10.6 1.9 2 0 0 2 2 2 0 Tropomyosin Nup54 PF13874.1 EER25037.1 - 0.16 11.6 11.4 0.08 12.6 2.2 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Sec20 PF03908.8 EER25037.1 - 0.19 11.4 3.3 1.6 8.4 0.5 2.3 1 1 1 2 2 2 0 Sec20 V_ATPase_I PF01496.14 EER25037.1 - 3.5 5.3 7.8 4.5 4.9 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EER25037.1 - 4.4 7.0 11.2 1.1 8.9 1.5 2.6 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 KIAA1430 PF13879.1 EER25037.1 - 5 7.6 8.8 0.79 10.1 0.4 2.3 2 1 1 3 3 3 0 KIAA1430 homologue NYD-SP28_assoc PF14775.1 EER25037.1 - 7.1 6.4 7.5 36 4.1 1.7 3.2 2 1 0 2 2 2 0 Sperm tail C-terminal domain DOT1 PF08123.8 EER25038.1 - 2.3e-77 258.9 0.0 3.2e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EER25038.1 - 0.00025 21.0 0.0 0.00053 19.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER25038.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER25038.1 - 0.012 16.1 0.1 0.048 14.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PH PF00169.24 EER25039.1 - 1.2e-11 44.7 0.2 1.7e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EER25039.1 - 4.4e-05 23.6 2.4 0.00034 20.8 1.7 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EER25039.1 - 0.0022 18.1 0.2 0.026 14.6 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain Glyco_transf_15 PF01793.11 EER25040.1 - 1.9e-131 437.9 1.3 2.5e-131 437.5 0.9 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Ran_BP1 PF00638.13 EER25042.1 - 1.7e-50 170.1 1.8 2.6e-50 169.5 1.2 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EER25042.1 - 3.8e-06 26.6 0.6 2.3e-05 24.0 0.4 1.9 1 1 0 1 1 1 1 WH1 domain FHIPEP PF00771.15 EER25042.1 - 0.088 11.1 0.6 0.12 10.7 0.4 1.2 1 0 0 1 1 1 0 FHIPEP family RNA_pol_Rpc82 PF05645.8 EER25042.1 - 8.5 5.8 10.3 6.7 6.1 4.9 2.1 1 1 1 2 2 2 0 RNA polymerase III subunit RPC82 YEATS PF03366.11 EER25043.1 - 1.2e-20 72.9 0.1 2.2e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 YEATS family IstB_IS21 PF01695.12 EER25044.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Nol1_Nop2_Fmu PF01189.12 EER25045.1 - 3.2e-14 52.9 0.0 1.3e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 NOL1/NOP2/sun family PB1 PF00564.19 EER25045.1 - 0.16 11.6 0.0 6.2 6.5 0.0 2.5 2 0 0 2 2 2 0 PB1 domain Phosducin PF02114.11 EER25046.1 - 9.7e-14 50.7 1.3 8.4e-13 47.6 0.0 2.5 2 1 0 2 2 2 1 Phosducin POPLD PF08170.7 EER25046.1 - 0.3 10.9 2.1 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 POPLD (NUC188) domain CAP59_mtransfer PF11735.3 EER25047.1 - 7e-71 238.2 0.0 9.5e-71 237.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 2-Hacid_dh_C PF02826.14 EER25048.1 - 5.4e-53 178.7 0.0 7e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER25048.1 - 8.9e-16 57.5 0.0 1.1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EER25048.1 - 5e-05 23.2 0.0 9.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EER25048.1 - 0.0033 17.8 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent WD40 PF00400.27 EER25049.1 - 6.8e-49 162.0 22.4 1.3e-08 34.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EER25049.1 - 4.5e-05 23.2 0.0 0.091 12.4 0.0 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-MYND PF01753.13 EER25050.1 - 1.8e-07 30.9 20.5 1.8e-07 30.9 14.2 1.9 2 0 0 2 2 2 1 MYND finger DIOX_N PF14226.1 EER25051.1 - 2.1e-19 70.1 0.1 3.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EER25051.1 - 1.6e-14 53.9 0.0 4.1e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 EER25052.1 - 8.7e-74 247.5 0.0 1.2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EER25052.1 - 5e-31 106.8 0.0 1.4e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EER25052.1 - 4.7e-12 45.7 0.0 9.4e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EER25052.1 - 0.025 14.8 0.0 0.067 13.4 0.0 1.8 1 0 0 1 1 1 0 XPG N-terminal domain Thioredoxin PF00085.15 EER25053.1 - 2.6e-58 194.1 0.0 2.1e-28 98.0 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EER25053.1 - 1.5e-24 86.4 0.6 1.4e-23 83.3 0.2 2.4 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EER25053.1 - 7e-17 61.6 0.0 3.6e-08 33.5 0.0 3.4 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EER25053.1 - 2.3e-11 43.5 0.0 7.1e-06 25.9 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EER25053.1 - 1.1e-10 41.4 0.0 0.0002 21.4 0.0 3.2 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EER25053.1 - 1.9e-08 34.0 0.0 0.0059 16.2 0.0 2.3 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_4 PF13462.1 EER25053.1 - 3.6e-05 23.8 0.4 1.8 8.5 0.0 4.2 3 2 1 5 5 5 2 Thioredoxin Thioredoxin_9 PF14595.1 EER25053.1 - 0.00035 20.1 0.0 0.46 10.0 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Redoxin PF08534.5 EER25053.1 - 0.00047 19.7 0.1 0.93 9.0 0.0 2.4 2 0 0 2 2 2 2 Redoxin Ebp2 PF05890.7 EER25054.1 - 9.6e-97 323.5 13.8 9.6e-97 323.5 9.6 2.1 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Daxx PF03344.10 EER25054.1 - 2.2 6.6 32.5 3 6.2 22.5 1.2 1 0 0 1 1 1 0 Daxx Family TruB_N PF01509.13 EER25056.1 - 4.1e-45 153.5 0.0 1.4e-44 151.9 0.0 1.8 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Mating_C PF12737.2 EER25056.1 - 3.7 6.3 16.6 0.031 13.1 5.5 1.7 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 FHA PF00498.21 EER25058.1 - 2.8e-14 52.9 0.0 7e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EER25058.1 - 2.9e-06 26.9 10.1 6e-06 25.9 7.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EER25058.1 - 0.0001 22.3 5.5 0.00026 21.0 3.4 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EER25058.1 - 0.0046 16.6 7.4 0.0086 15.7 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EER25058.1 - 0.017 14.7 9.4 0.036 13.7 6.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EER25058.1 - 0.018 14.8 3.8 0.045 13.5 2.1 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EER25058.1 - 0.072 13.1 10.5 0.14 12.2 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EER25058.1 - 0.099 12.6 6.5 0.23 11.5 4.5 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EER25058.1 - 3.2 7.7 8.9 4.4 7.2 5.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Bestrophin PF01062.16 EER25059.1 - 6.9e-43 146.6 0.0 1.5e-42 145.5 0.0 1.5 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Vps16_N PF04841.8 EER25061.1 - 1.1e-99 333.7 0.0 1.5e-99 333.3 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EER25061.1 - 6.3e-83 278.3 0.0 9.2e-83 277.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Alb1 PF09135.6 EER25062.1 - 1e-32 113.0 10.3 1.8e-32 112.2 7.1 1.4 1 0 0 1 1 1 1 Alb1 Pkinase PF00069.20 EER25063.1 - 3.4e-75 252.5 0.0 3.9e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25063.1 - 1.7e-34 119.0 0.0 2.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EER25063.1 - 0.0051 16.1 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EER25063.1 - 0.0069 16.1 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EER25063.1 - 0.012 14.6 0.0 0.031 13.2 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 EER25063.1 - 0.015 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EER25063.1 - 0.022 13.5 0.1 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Seadornavirus VP7 RhoGAP PF00620.22 EER25064.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.7 1 1 0 1 1 1 0 RhoGAP domain CBS PF00571.23 EER25065.1 - 3.4e-27 93.9 4.3 3.6e-11 42.6 0.1 4.2 4 0 0 4 4 4 4 CBS domain CRAL_TRIO PF00650.15 EER25066.1 - 2.8e-37 127.6 0.0 3.8e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EER25066.1 - 2.6e-14 53.0 2.0 3e-14 52.8 0.0 2.2 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EER25066.1 - 0.0002 21.2 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EER25067.1 - 2.1e-60 204.4 0.3 3.9e-60 203.5 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EER25067.1 - 4.5e-40 137.1 0.0 6.2e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B IF-2B PF01008.12 EER25068.1 - 6.6e-78 261.5 0.3 8.7e-78 261.1 0.2 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family rve_2 PF13333.1 EER25068.1 - 0.19 11.7 0.1 0.92 9.6 0.1 2.0 2 0 0 2 2 2 0 Integrase core domain Kinesin PF00225.18 EER25069.1 - 6.4e-114 380.1 0.0 1.1e-113 379.3 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain V_ATPase_I PF01496.14 EER25069.1 - 0.23 9.2 7.0 0.35 8.6 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ACCA PF03255.9 EER25069.1 - 0.37 10.3 4.3 0.95 9.0 2.5 2.1 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Mnd1 PF03962.10 EER25069.1 - 0.59 9.7 10.9 1.4 8.5 7.6 1.6 1 0 0 1 1 1 0 Mnd1 family DUF87 PF01935.12 EER25069.1 - 0.98 9.1 7.0 0.74 9.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 GAGA_bind PF06217.7 EER25069.1 - 2 8.3 8.5 4.1 7.2 5.9 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family PUL PF08324.6 EER25070.1 - 1.1e-37 129.3 0.1 1.4e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EER25070.1 - 7e-36 123.2 0.0 1.3e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EER25070.1 - 2.6e-16 59.1 0.0 4.9e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EER25070.1 - 0.00029 21.0 1.2 0.00091 19.4 0.3 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EER25070.1 - 0.00094 18.9 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin domain DUF2847 PF11009.3 EER25070.1 - 0.0022 17.5 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) AhpC-TSA PF00578.16 EER25070.1 - 0.0073 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family TraF PF13728.1 EER25070.1 - 0.008 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein T4_deiodinase PF00837.12 EER25070.1 - 0.027 13.5 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Iodothyronine deiodinase Thioredoxin_8 PF13905.1 EER25070.1 - 0.062 13.4 0.0 0.39 10.8 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Redoxin PF08534.5 EER25070.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Redoxin EF-hand_9 PF14658.1 EER25071.1 - 0.0043 16.9 0.0 1.3 8.9 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain DUF4343 PF14243.1 EER25071.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) EF-hand_8 PF13833.1 EER25071.1 - 0.042 13.4 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain pair ORC6 PF05460.8 EER25071.1 - 0.072 12.1 2.3 0.12 11.4 1.6 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Peptidase_S24 PF00717.18 EER25072.1 - 1.6e-09 37.2 0.2 2.9e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EER25072.1 - 0.0001 21.8 0.0 0.0069 15.9 0.0 2.5 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Sipho_Gp37 PF14594.1 EER25072.1 - 0.023 13.9 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein PBP PF01161.15 EER25073.1 - 1.4e-12 47.7 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ribosomal_L4 PF00573.17 EER25074.1 - 1.2e-48 165.0 0.0 1.6e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family ECH_C PF13766.1 EER25075.1 - 6.6e-43 145.6 0.1 1.5e-42 144.4 0.0 1.6 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EER25075.1 - 9.8e-26 90.3 0.0 2.8e-25 88.8 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF1264 PF06884.6 EER25076.1 - 1.6e-73 245.7 0.1 2.1e-73 245.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Lactamase_B PF00753.22 EER25077.1 - 7.6e-30 104.0 1.8 9.4e-30 103.7 1.2 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EER25077.1 - 8.7e-06 25.4 0.3 1.4e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EER25077.1 - 0.0018 17.6 0.1 0.006 15.9 0.0 1.8 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Lactamase_B_3 PF13483.1 EER25077.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Las1 PF04031.8 EER25078.1 - 1.1e-43 148.5 0.0 2.2e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 Las1-like Ubiq-assoc PF09145.5 EER25078.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-associated NAD_kinase PF01513.16 EER25080.1 - 7.6e-69 231.6 0.0 1e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.11 EER25081.1 - 3.4e-34 117.5 0.0 4.6e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Prp19_bind PF06991.6 EER25082.1 - 1.1e-41 142.9 21.9 1.1e-41 142.9 15.2 2.4 1 1 0 2 2 2 1 Splicing factor, Prp19-binding domain Glyco_hydro_16 PF00722.16 EER25083.1 - 6.7e-43 146.1 2.5 1.1e-42 145.4 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1191 PF06697.7 EER25083.1 - 0.02 13.7 0.3 0.1 11.3 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1191) Rep_fac-A_3 PF08661.6 EER25084.1 - 3e-26 91.4 0.0 3.5e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.2 EER25084.1 - 0.028 14.1 0.1 0.61 9.8 0.0 2.0 1 1 0 1 1 1 0 Telomere capping, CST complex subunit GATA PF00320.22 EER25085.1 - 3.8e-05 22.9 5.1 0.0014 17.9 0.8 2.6 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.17 EER25086.1 - 1.8e-07 30.5 0.0 2e-07 30.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain Dak1 PF02733.12 EER25087.1 - 9.9e-115 382.5 1.4 1.4e-114 382.0 0.9 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EER25087.1 - 6.8e-44 149.6 0.0 1.3e-43 148.6 0.0 1.5 1 0 0 1 1 1 1 DAK2 domain Cullin PF00888.17 EER25088.1 - 3.3e-125 418.9 4.2 4.3e-125 418.5 2.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EER25088.1 - 5e-25 87.1 1.6 1.4e-24 85.6 1.1 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain HbrB PF08539.6 EER25088.1 - 0.00017 21.5 0.1 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 HbrB-like DUF3414 PF11894.3 EER25089.1 - 0 1406.2 19.3 0 1405.7 13.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) PI3_PI4_kinase PF00454.22 EER25090.1 - 1e-47 162.6 0.1 2e-47 161.6 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EER25090.1 - 4.2e-32 111.0 0.0 6.5e-31 107.1 0.0 3.2 2 1 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EER25090.1 - 1.3e-11 43.6 0.1 1.3e-11 43.6 0.1 2.5 3 0 0 3 3 3 1 FATC domain TPR_11 PF13414.1 EER25090.1 - 0.011 15.3 0.0 0.033 13.8 0.0 1.8 1 0 0 1 1 1 0 TPR repeat 2OG-FeII_Oxy_3 PF13640.1 EER25093.1 - 0.092 13.2 0.3 0.54 10.7 0.0 2.3 3 0 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily UPF0052 PF01933.13 EER25095.1 - 2.3e-51 174.8 0.0 3.1e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_3 PF13920.1 EER25096.1 - 4.9e-10 38.9 5.6 7e-10 38.4 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER25096.1 - 1.6e-09 37.6 6.2 3e-09 36.7 4.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER25096.1 - 2.5e-09 36.8 6.9 3.8e-09 36.2 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EER25096.1 - 2.6e-09 36.6 3.9 5.6e-09 35.5 2.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER25096.1 - 9.5e-08 31.6 6.9 1.6e-07 30.9 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EER25096.1 - 4.8e-05 23.1 7.3 5.6e-05 22.9 2.1 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EER25096.1 - 0.00044 19.9 5.9 0.0031 17.2 1.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EER25096.1 - 0.0071 16.4 2.0 0.012 15.7 1.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-4CXXC_R1 PF10497.4 EER25096.1 - 0.011 15.8 4.1 0.043 13.9 2.9 1.8 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Rad50_zn_hook PF04423.9 EER25096.1 - 0.019 14.4 0.7 0.95 8.9 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-nanos PF05741.8 EER25096.1 - 0.078 12.9 0.3 0.078 12.9 0.2 2.3 2 1 1 3 3 3 0 Nanos RNA binding domain zf-Apc11 PF12861.2 EER25096.1 - 0.3 10.9 4.0 0.86 9.4 2.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EER25096.1 - 1 8.9 7.9 5 6.7 5.6 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-FPG_IleRS PF06827.9 EER25096.1 - 1.3 8.7 4.8 14 5.4 0.4 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF1644 PF07800.7 EER25096.1 - 1.4 8.7 6.9 0.79 9.5 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Prok-RING_4 PF14447.1 EER25096.1 - 1.6 8.3 6.7 4.9 6.7 2.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EER25096.1 - 9.6 6.0 8.4 8.1 6.3 3.3 2.4 2 1 0 2 2 2 0 zf-RING of BARD1-type protein DNA_pol_A PF00476.15 EER25097.1 - 6.1e-101 337.8 0.0 8.2e-101 337.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A CorA PF01544.13 EER25098.1 - 7.5e-26 90.8 5.2 1.4e-19 70.2 1.4 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein SQS_PSY PF00494.14 EER25099.1 - 2.1e-47 161.6 0.0 2.8e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase LSM PF01423.17 EER25100.1 - 9.5e-18 63.5 0.4 1.3e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain GTP_EFTU PF00009.22 EER25101.1 - 7.7e-22 77.6 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EER25101.1 - 1.1e-15 57.6 0.0 2.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EER25101.1 - 1.4e-09 37.9 1.9 1.4e-08 34.7 1.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EER25101.1 - 0.00077 18.9 0.4 0.44 10.0 0.1 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EER25101.1 - 0.0089 15.9 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER25101.1 - 0.01 16.3 0.1 0.1 13.0 0.1 2.6 2 1 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EER25101.1 - 0.04 13.7 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 EER25101.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EER25101.1 - 0.95 9.0 3.2 4.4 6.9 0.0 2.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain SNF2_N PF00176.18 EER25103.1 - 2.4e-66 223.5 0.0 3.5e-66 223.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EER25103.1 - 4.4e-22 78.0 0.0 8.6e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EER25103.1 - 3.5e-15 55.6 0.0 2.7e-14 52.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EER25103.1 - 2.4e-07 30.6 9.0 4.7e-07 29.7 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER25103.1 - 3.8e-05 23.2 5.9 7.2e-05 22.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER25103.1 - 0.00019 21.0 9.5 0.00038 20.0 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER25103.1 - 0.00044 20.0 7.8 0.00091 19.0 5.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EER25103.1 - 0.00049 19.7 7.7 0.001 18.7 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain UBA_4 PF14555.1 EER25103.1 - 0.0018 17.7 0.7 0.73 9.4 0.0 2.7 2 0 0 2 2 2 2 UBA-like domain zf-C3HC4_4 PF15227.1 EER25103.1 - 0.05 13.4 7.9 0.1 12.5 5.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EER25103.1 - 0.082 12.6 6.2 0.24 11.1 4.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger ATP13 PF12921.2 EER25104.1 - 1e-27 95.9 0.0 2.2e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_2 PF13041.1 EER25104.1 - 9.9e-09 35.0 0.0 0.00012 22.0 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 EER25104.1 - 0.00033 20.6 0.2 0.22 11.8 0.0 4.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EER25104.1 - 0.0099 15.7 0.9 0.18 11.8 0.1 3.1 3 0 0 3 3 3 1 PPR repeat PIG-L PF02585.12 EER25105.1 - 1.2e-27 96.8 0.0 1.9e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase PrgI PF12666.2 EER25106.1 - 0.41 10.8 5.5 0.11 12.7 1.0 1.9 2 0 0 2 2 2 0 PrgI family protein MASE2 PF05230.6 EER25107.1 - 0.039 13.9 1.5 0.066 13.1 1.1 1.4 1 0 0 1 1 1 0 MASE2 domain DUF3153 PF11353.3 EER25107.1 - 0.078 12.4 0.5 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Mei4 PF13971.1 EER25108.1 - 0.0011 18.0 0.3 0.0012 17.9 0.2 1.1 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 DnaJ PF00226.26 EER25109.1 - 4e-19 68.0 0.8 4e-19 68.0 0.6 1.8 2 0 0 2 2 2 1 DnaJ domain RRM_1 PF00076.17 EER25109.1 - 0.083 12.5 0.1 0.43 10.2 0.1 2.1 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DCP2 PF05026.8 EER25110.1 - 1.4e-35 121.0 1.9 2.7e-35 120.0 1.3 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EER25110.1 - 1e-14 54.3 0.0 2.4e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain GCV_T PF01571.16 EER25110.1 - 1.3e-14 54.0 0.0 3.6e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EER25110.1 - 0.0043 17.0 0.0 0.016 15.2 0.0 2.0 2 0 0 2 2 2 1 Glycine cleavage T-protein C-terminal barrel domain DUF4112 PF13430.1 EER25111.1 - 7.4e-35 119.0 0.2 9.5e-35 118.7 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) HSP70 PF00012.15 EER25112.1 - 0.029 12.3 1.3 2.1 6.1 0.0 2.9 3 0 0 3 3 3 0 Hsp70 protein SDA1 PF05285.7 EER25112.1 - 1.6 7.9 5.3 2.4 7.3 3.7 1.2 1 0 0 1 1 1 0 SDA1 Pol_alpha_B_N PF08418.5 EER25113.1 - 0.021 14.3 4.0 0.032 13.7 2.8 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Jnk-SapK_ap_N PF09744.4 EER25113.1 - 0.074 13.0 7.2 0.031 14.2 3.1 1.8 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 IncA PF04156.9 EER25113.1 - 9.8 5.7 9.7 4.3 6.8 4.1 2.1 2 0 0 2 2 2 0 IncA protein Glyco_hydro_47 PF01532.15 EER25115.1 - 3.7e-173 576.3 0.0 4.3e-173 576.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EER25115.1 - 0.0065 14.7 0.0 0.25 9.5 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) C5-epim_C PF06662.8 EER25115.1 - 0.077 12.2 0.2 5.2 6.3 0.0 3.2 4 0 0 4 4 4 0 D-glucuronyl C5-epimerase C-terminus DUF2392 PF10288.4 EER25116.1 - 1.2e-27 96.3 0.0 2e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Lung_7-TM_R PF06814.8 EER25117.1 - 1.2e-71 241.0 18.8 1.5e-71 240.7 13.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 EER25117.1 - 1.1 9.4 21.8 0.56 10.3 1.0 3.5 2 2 1 3 3 3 0 PrgI family protein DUF2929 PF11151.3 EER25117.1 - 4.7 7.3 13.2 10 6.2 0.4 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2929) CHAT PF12770.2 EER25119.1 - 3.3e-20 72.3 0.0 5.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 CHAT domain Raptor_N PF14538.1 EER25119.1 - 0.061 13.1 0.0 0.7 9.7 0.0 2.2 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain ABC_tran PF00005.22 EER25120.1 - 3e-13 50.2 0.1 2.7e-12 47.1 0.0 2.2 2 0 0 2 2 2 1 ABC transporter DivIC PF04977.10 EER25120.1 - 0.011 15.1 1.9 0.011 15.1 1.3 2.1 2 0 0 2 2 2 0 Septum formation initiator XhlA PF10779.4 EER25120.1 - 0.038 13.9 2.8 0.13 12.2 1.9 1.9 1 0 0 1 1 1 0 Haemolysin XhlA DUF258 PF03193.11 EER25120.1 - 0.12 11.5 0.0 0.26 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TMF_DNA_bd PF12329.3 EER25120.1 - 0.31 10.8 5.0 0.11 12.3 1.5 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 EER25120.1 - 1.7 8.6 5.0 2.6 8.0 1.4 2.5 2 0 0 2 2 2 0 bZIP transcription factor DUF1308 PF07000.6 EER25121.1 - 1.8e-83 280.1 0.2 2.5e-83 279.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) WD40 PF00400.27 EER25122.1 - 1.5e-13 50.0 4.5 2.3e-07 30.4 0.1 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EER25122.1 - 0.00043 18.6 0.0 2.7 6.1 0.1 3.5 2 1 2 4 4 4 2 Cytochrome D1 heme domain MRG PF05712.8 EER25122.1 - 0.055 12.3 0.0 0.079 11.8 0.0 1.2 1 0 0 1 1 1 0 MRG DUF4263 PF14082.1 EER25122.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4263) Mito_carr PF00153.22 EER25123.1 - 5.4e-57 189.5 2.9 5.6e-20 70.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_red_sm PF00268.16 EER25124.1 - 9.3e-121 402.1 0.3 1.1e-120 401.8 0.2 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF1220 PF06758.8 EER25124.1 - 0.076 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) SRP9-21 PF05486.7 EER25126.1 - 3e-29 100.5 2.9 4.9e-29 99.8 2.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) OHCU_decarbox PF09349.5 EER25127.1 - 5.8e-36 124.1 0.0 6.9e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase RPAP1_C PF08620.5 EER25127.1 - 0.14 12.0 0.3 2 8.3 0.2 2.3 1 1 1 2 2 2 0 RPAP1-like, C-terminal WD40 PF00400.27 EER25128.1 - 1.3e-28 97.7 9.9 1.3e-08 34.4 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Arm PF00514.18 EER25129.1 - 1.1e-71 234.3 28.9 1.1e-12 47.2 0.1 11.5 12 0 0 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EER25129.1 - 2.4e-23 82.1 13.3 7.7e-08 32.5 0.5 7.5 3 2 1 6 6 6 4 HEAT repeats HEAT PF02985.17 EER25129.1 - 1.1e-19 68.6 13.3 0.016 15.2 0.0 9.9 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EER25129.1 - 7.3e-16 58.1 15.5 0.009 16.4 0.1 8.5 8 2 2 10 10 10 5 HEAT-like repeat Adaptin_N PF01602.15 EER25129.1 - 4.8e-13 48.2 8.9 1.3e-07 30.3 0.4 2.6 1 1 2 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 EER25129.1 - 1.5e-10 40.5 6.4 1.5e-06 27.5 2.0 3.0 1 1 0 2 2 2 2 Armadillo-like KAP PF05804.7 EER25129.1 - 8e-10 37.2 0.1 1.4e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EER25129.1 - 1.5e-08 34.1 1.4 0.00013 21.2 0.3 2.7 1 1 1 2 2 2 2 V-ATPase subunit H HEAT_PBS PF03130.11 EER25129.1 - 0.00021 21.4 7.7 1.1 9.9 0.4 6.8 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat DUF908 PF06012.7 EER25129.1 - 0.00079 18.8 6.4 0.44 9.8 0.1 4.3 3 1 2 5 5 5 1 Domain of Unknown Function (DUF908) V-ATPase_H_C PF11698.3 EER25129.1 - 0.0031 17.3 2.1 2.5 8.0 0.0 4.4 1 1 5 6 6 6 1 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EER25129.1 - 0.036 14.4 0.0 1.2 9.5 0.0 3.3 2 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region EXOSC1 PF10447.4 EER25130.1 - 7.1e-24 83.5 0.2 1.1e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EER25130.1 - 1.7e-14 52.7 0.1 1.7e-14 52.7 0.1 2.0 3 0 0 3 3 3 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EER25130.1 - 0.031 14.3 0.2 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 S1 RNA binding domain GTP_EFTU PF00009.22 EER25131.1 - 1.4e-52 177.8 0.0 2.7e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EER25131.1 - 1.5e-15 56.7 0.0 4.3e-15 55.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EER25131.1 - 2.8e-08 33.7 0.0 6.9e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EER25131.1 - 5e-08 32.6 0.0 1.1e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EER25131.1 - 2.5e-06 27.0 0.0 0.0011 18.5 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G, domain IV DUF4604 PF15377.1 EER25132.1 - 9.5e-26 90.9 20.2 1.2e-25 90.5 14.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) FLO_LFY PF01698.11 EER25132.1 - 0.94 8.2 7.4 1.1 7.9 5.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DRY_EERY PF09750.4 EER25132.1 - 4.2 7.4 7.7 0.43 10.6 1.2 2.0 2 0 0 2 2 2 0 Alternative splicing regulator Prp19 PF08606.6 EER25133.1 - 8.1e-32 108.7 1.2 1.5e-31 107.9 0.8 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EER25133.1 - 8.2e-16 57.2 6.2 7.8e-06 25.5 0.0 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat DUF3312 PF11768.3 EER25133.1 - 0.0072 14.6 0.1 0.018 13.2 0.1 1.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3312) zf-Nse PF11789.3 EER25133.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Cytochrom_D1 PF02239.11 EER25133.1 - 0.027 12.7 0.7 1.3 7.2 0.1 2.7 1 1 2 3 3 3 0 Cytochrome D1 heme domain zf-RING_5 PF14634.1 EER25134.1 - 0.0018 17.9 2.0 0.0041 16.8 1.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.16 EER25134.1 - 0.054 13.3 3.2 0.11 12.4 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger BIR PF00653.16 EER25134.1 - 0.058 13.8 0.5 0.12 12.8 0.0 1.7 1 1 1 2 2 2 0 Inhibitor of Apoptosis domain zf-C3HC4_2 PF13923.1 EER25134.1 - 0.12 12.4 6.2 0.83 9.7 4.4 2.3 1 1 2 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER25134.1 - 0.19 11.4 2.1 0.67 9.6 1.6 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER25134.1 - 0.66 9.8 4.2 1.1 9.1 2.0 2.1 1 1 1 2 2 2 0 Ring finger domain zf-UBP PF02148.14 EER25134.1 - 0.99 9.5 4.6 0.48 10.5 1.1 1.9 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein L51_S25_CI-B8 PF05047.11 EER25135.1 - 1.7e-15 56.5 0.2 1.7e-15 56.5 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EER25136.1 - 2.5e-34 117.4 1.6 4.3e-34 116.6 1.1 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EER25136.1 - 4.8e-17 61.3 0.0 1.1e-16 60.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER25136.1 - 3.6e-11 42.8 0.0 6.4e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25136.1 - 1.5e-06 27.9 0.0 3.2e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 EER25137.1 - 4.5e-18 65.0 0.0 1e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 DUF3722 PF12519.3 EER25138.1 - 3.9e-90 301.5 5.9 4.9e-90 301.2 4.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) TIM PF00121.13 EER25139.1 - 3.8e-88 294.6 0.0 4.3e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 EER25139.1 - 0.024 13.9 0.1 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 CutC family DUF3552 PF12072.3 EER25140.1 - 0.24 10.5 8.2 0.52 9.5 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Sugar_tr PF00083.19 EER25141.1 - 9.8e-85 284.7 26.9 1.1e-84 284.5 18.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER25141.1 - 2.5e-29 102.1 40.9 5.3e-24 84.5 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EER25142.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Pro_isomerase PF00160.16 EER25143.1 - 1.6e-39 135.5 0.0 4.2e-39 134.2 0.0 1.7 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EER25143.1 - 9.5e-06 25.4 0.0 3.6e-05 23.6 0.0 2.0 1 1 1 2 2 2 1 U-box domain Rtf2 PF04641.7 EER25143.1 - 2e-05 23.9 1.4 6.3e-05 22.3 0.0 2.2 2 1 0 2 2 2 1 Rtf2 RING-finger DUF3602 PF12223.3 EER25143.1 - 0.047 14.0 0.0 0.047 14.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3602) hNIFK_binding PF12196.3 EER25143.1 - 1.7 8.0 3.8 28 4.2 0.5 2.6 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Epimerase PF01370.16 EER25144.1 - 8.5e-15 54.8 0.0 1.1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EER25144.1 - 2.4e-12 46.1 0.0 2.1e-11 43.0 0.0 1.9 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EER25144.1 - 6.8e-09 35.9 0.1 2.9e-08 33.9 0.0 2.0 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EER25144.1 - 1.1e-06 28.0 0.0 1.8e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EER25144.1 - 3e-05 23.0 0.0 0.0003 19.7 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EER25144.1 - 0.00026 19.9 0.0 0.088 11.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EER25144.1 - 0.0015 18.5 0.1 0.0099 15.8 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EER25144.1 - 0.0033 16.3 0.1 1.1 8.0 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.5 EER25144.1 - 0.16 11.6 0.6 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 KR domain YjeF_N PF03853.10 EER25145.1 - 1.1e-33 116.2 0.1 1.7e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EER25145.1 - 1.9e-10 41.2 1.1 1.9e-10 41.2 0.7 2.0 2 0 0 2 2 2 1 FDF domain NTP_transferase PF00483.18 EER25145.1 - 0.025 13.8 0.0 0.048 12.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase PIF1 PF05970.9 EER25146.1 - 3.9e-63 213.6 0.1 5.1e-48 163.8 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EER25146.1 - 1.4e-17 63.9 0.0 2.5e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EER25146.1 - 5.5e-07 29.7 0.0 1.2e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER25146.1 - 4.7e-06 26.2 0.1 9.4e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EER25146.1 - 2.8e-05 22.1 0.0 0.0003 18.7 0.0 2.3 3 0 0 3 3 3 1 Helicase UvrD_C_2 PF13538.1 EER25146.1 - 7.2e-05 22.8 0.1 0.00078 19.5 0.1 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EER25146.1 - 0.0034 17.3 0.7 0.039 13.9 0.0 2.6 2 1 0 3 3 2 1 AAA ATPase domain PhoH PF02562.11 EER25146.1 - 0.0035 16.5 0.1 0.01 15.0 0.0 1.8 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.24 EER25146.1 - 0.006 16.7 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EER25146.1 - 0.024 14.2 0.1 0.69 9.4 0.0 2.7 1 1 0 2 2 2 0 AAA domain AAA_7 PF12775.2 EER25146.1 - 0.029 13.4 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 Mg_chelatase PF01078.16 EER25146.1 - 0.031 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EER25146.1 - 0.05 12.4 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EER25146.1 - 0.062 13.4 0.1 0.29 11.3 0.0 2.3 2 1 0 2 2 2 0 RNA helicase DUF2075 PF09848.4 EER25146.1 - 0.092 11.6 0.1 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EER25146.1 - 0.11 12.7 0.1 0.53 10.5 0.1 2.0 1 1 0 2 2 2 0 ABC transporter TrwB_AAD_bind PF10412.4 EER25146.1 - 0.12 10.9 0.1 0.21 10.1 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Arch_ATPase PF01637.13 EER25146.1 - 0.14 11.8 0.3 0.45 10.1 0.2 1.8 1 1 0 1 1 1 0 Archaeal ATPase PTCB-BRCT PF12738.2 EER25147.1 - 1.2e-46 156.3 0.5 1.7e-19 69.4 0.0 3.6 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EER25147.1 - 4.6e-31 106.8 0.1 5.3e-11 42.5 0.0 4.4 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain Dynamin_N PF00350.18 EER25148.1 - 2.7e-18 66.3 0.7 7e-18 64.9 0.1 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EER25148.1 - 2.2e-09 37.2 0.1 1e-08 35.1 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER25148.1 - 1.1e-06 28.2 0.5 9.2e-06 25.2 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EER25148.1 - 0.0051 17.3 0.2 0.49 10.8 0.1 3.1 1 1 0 1 1 1 1 Miro-like protein IIGP PF05049.8 EER25148.1 - 0.025 13.3 0.0 0.047 12.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EER25148.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Snf7 PF03357.16 EER25149.1 - 1.9e-35 121.7 16.7 5.5e-35 120.2 11.4 1.7 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EER25149.1 - 0.0061 14.4 3.7 0.0074 14.2 2.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EER25149.1 - 0.24 10.8 5.5 0.36 10.2 3.8 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Remorin_C PF03763.8 EER25149.1 - 3.4 7.2 8.8 7.9 6.0 6.1 1.8 1 1 0 1 1 1 0 Remorin, C-terminal region TPR_MLP1_2 PF07926.7 EER25149.1 - 4 7.1 11.5 9.8 5.9 7.9 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PP2C PF00481.16 EER25150.1 - 1.9e-61 207.7 0.0 2.4e-50 171.3 0.0 3.2 3 0 0 3 3 3 3 Protein phosphatase 2C Mhr1 PF12829.2 EER25151.1 - 2.1e-30 104.3 0.6 6e-30 102.9 0.0 2.0 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination DUF4355 PF14265.1 EER25151.1 - 0.015 15.2 11.7 0.041 13.8 8.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1974 PF09317.6 EER25151.1 - 0.06 12.7 5.0 0.11 11.9 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Ribosomal_S9 PF00380.14 EER25151.1 - 0.49 10.6 5.3 0.37 11.0 2.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S9/S16 PRP1_N PF06424.7 EER25151.1 - 5.6 7.2 9.1 20 5.4 6.4 1.9 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal Atg14 PF10186.4 EER25152.1 - 4.4e-25 88.2 1.5 6.6e-25 87.6 1.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 IL6 PF00489.12 EER25152.1 - 0.0061 16.1 1.1 0.011 15.3 0.8 1.4 1 0 0 1 1 1 1 Interleukin-6/G-CSF/MGF family APG6 PF04111.7 EER25152.1 - 0.041 12.9 11.5 0.33 9.9 8.0 2.0 1 1 0 1 1 1 0 Autophagy protein Apg6 Thioredoxin_5 PF13743.1 EER25152.1 - 0.66 9.5 4.9 1.1 8.7 3.4 1.2 1 0 0 1 1 1 0 Thioredoxin Zn_clus PF00172.13 EER25153.1 - 7.3e-07 28.9 14.8 7.3e-07 28.9 10.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_2 PF00891.13 EER25154.1 - 2.8e-30 105.2 0.0 3.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EER25154.1 - 0.0005 19.8 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain F-box-like PF12937.2 EER25155.1 - 1.2e-05 24.9 0.2 1.2e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like PalH PF08733.5 EER25156.1 - 1.1e-102 343.4 2.8 7.1e-102 340.7 2.0 1.9 1 1 0 1 1 1 1 PalH/RIM21 PLAC8 PF04749.12 EER25157.1 - 2.4e-21 76.2 17.5 3.3e-21 75.8 12.1 1.2 1 0 0 1 1 1 1 PLAC8 family TIP120 PF08623.5 EER25158.1 - 1.4e-61 206.9 2.7 3.6e-61 205.6 0.1 3.1 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EER25158.1 - 2.2e-13 50.2 21.3 0.012 15.8 0.0 7.9 7 2 2 9 9 9 4 HEAT repeats HEAT PF02985.17 EER25158.1 - 2.2e-10 39.7 14.7 0.58 10.3 0.0 11.2 11 0 0 11 11 11 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EER25158.1 - 2.6e-05 24.5 0.0 0.3 11.4 0.0 4.9 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EER25158.1 - 0.00016 20.1 6.8 2.4 6.4 0.2 6.6 4 4 2 7 7 7 2 Adaptin N terminal region Cnd1 PF12717.2 EER25158.1 - 0.0027 17.5 0.3 0.052 13.4 0.0 3.4 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 EER25158.1 - 0.015 15.2 0.0 1.6 8.7 0.0 3.7 2 0 0 2 2 2 0 UME (NUC010) domain DUF2435 PF10363.4 EER25158.1 - 0.088 12.7 2.2 1.8 8.5 0.1 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) Arm PF00514.18 EER25158.1 - 0.23 11.3 5.3 1.1e+02 2.8 0.0 6.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.3 EER25158.1 - 2 7.0 11.6 10 4.7 0.8 5.2 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 EER25158.1 - 2.8 8.5 31.1 27 5.4 0.0 11.2 10 3 4 14 14 13 0 HEAT-like repeat TRAM_LAG1_CLN8 PF03798.11 EER25160.1 - 1.7e-34 119.0 21.2 3e-34 118.3 14.7 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EER25160.1 - 1.1e-23 82.4 0.1 2.9e-23 81.1 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein BSP_II PF05432.6 EER25160.1 - 0.041 13.1 10.0 0.056 12.7 7.0 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF1680 PF07944.7 EER25161.1 - 1.3e-18 66.6 0.1 1.4e-17 63.1 0.1 2.0 1 1 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Sugar_tr PF00083.19 EER25162.1 - 1.6e-110 369.7 19.6 2e-110 369.4 13.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER25162.1 - 7e-28 97.3 34.1 1.1e-26 93.4 18.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EER25162.1 - 4.2e-07 28.7 8.0 4.5e-06 25.3 0.4 3.7 4 0 0 4 4 4 2 MFS/sugar transport protein DUF791 PF05631.9 EER25162.1 - 0.00046 18.9 0.7 0.00098 17.9 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 EER25162.1 - 0.001 17.3 0.5 0.0023 16.2 0.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transglut_core PF01841.14 EER25163.1 - 6.5e-12 45.6 0.0 1.2e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EER25163.1 - 0.058 12.6 0.0 0.28 10.4 0.0 1.9 1 1 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.17 EER25164.1 - 3.1e-31 107.9 0.1 4e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER25164.1 - 4.2e-20 72.4 0.1 1.4e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EER25164.1 - 1.2e-06 27.9 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER25164.1 - 0.00013 21.1 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EER25164.1 - 0.071 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EER25164.1 - 0.087 11.4 0.5 0.2 10.3 0.0 1.8 1 1 0 1 1 1 0 G-protein alpha subunit WD40 PF00400.27 EER25165.1 - 1.3e-26 91.4 6.2 1.4e-10 40.6 0.1 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EER25165.1 - 1.3e-19 69.8 0.0 2.6e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EER25165.1 - 0.00082 17.6 3.6 0.0028 15.8 0.9 2.1 2 0 0 2 2 2 1 Nucleoporin Nup120/160 AAA PF00004.24 EER25167.1 - 1.9e-11 44.2 0.1 7.8e-10 39.0 0.1 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EER25167.1 - 9.3e-06 24.5 0.1 0.00027 19.7 0.0 2.3 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EER25167.1 - 2.7e-05 23.8 0.0 7e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EER25167.1 - 0.00017 22.3 0.0 0.00069 20.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EER25167.1 - 0.0005 20.2 0.0 0.0017 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER25167.1 - 0.0014 18.6 0.0 0.0039 17.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EER25167.1 - 0.0029 16.7 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EER25167.1 - 0.0049 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EER25167.1 - 0.03 14.2 0.0 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EER25167.1 - 0.069 12.2 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 EER25167.1 - 0.09 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 EER25167.1 - 0.098 12.5 0.0 0.4 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EER25167.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Fungal_trans PF04082.13 EER25169.1 - 2.1e-23 82.5 0.1 4.6e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EER25169.1 - 3.1e-10 39.7 12.9 4.5e-05 23.5 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER25169.1 - 5.5e-06 26.4 6.9 5.5e-06 26.4 4.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER25169.1 - 0.00017 21.7 16.7 0.014 15.7 2.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger ADH_zinc_N PF00107.21 EER25170.1 - 1.4e-07 31.0 0.0 2.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER25170.1 - 3.5e-05 24.6 0.0 0.00011 23.1 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase PX PF00787.19 EER25171.1 - 2.5e-17 62.7 0.1 4.9e-17 61.7 0.1 1.5 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.4 EER25171.1 - 0.028 13.0 1.5 0.067 11.7 1.0 1.7 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF3720 PF12517.3 EER25171.1 - 0.67 10.6 7.1 2.1 9.0 4.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3720) Nha1_C PF08619.5 EER25172.1 - 2.9e-86 290.4 23.9 4.2e-86 289.9 16.6 1.2 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EER25172.1 - 1.3e-65 221.3 20.8 1.6e-65 221.1 14.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EER25172.1 - 0.064 13.2 1.6 0.39 10.6 0.2 2.6 2 0 0 2 2 2 0 YrhC-like protein DUF21 PF01595.15 EER25172.1 - 1.5 8.0 10.1 0.03 13.6 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF21 Mpv17_PMP22 PF04117.7 EER25173.1 - 2.1e-12 46.4 0.7 1.8e-10 40.2 0.4 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family UPF0154 PF03672.8 EER25173.1 - 0.069 12.7 0.1 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) PEX11 PF05648.9 EER25174.1 - 3.3e-13 49.4 1.0 6.1e-13 48.5 0.5 1.5 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) SAP30_Sin3_bdg PF13867.1 EER25176.1 - 0.058 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 AAA PF00004.24 EER25178.1 - 4.7e-96 318.0 0.0 7e-47 158.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EER25178.1 - 8.2e-19 67.3 1.0 2e-18 66.0 0.5 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EER25178.1 - 6.5e-14 52.2 0.0 1.2e-07 31.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EER25178.1 - 5.3e-13 49.0 0.0 3.1e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EER25178.1 - 8.3e-13 47.9 0.0 3.2e-05 23.0 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EER25178.1 - 1.1e-11 44.5 0.4 9.2e-06 25.4 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EER25178.1 - 1.7e-11 44.9 0.0 0.00029 21.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EER25178.1 - 3.7e-11 43.2 0.2 0.0035 17.4 0.0 4.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EER25178.1 - 5.7e-10 39.4 0.0 0.0018 18.3 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain TIP49 PF06068.8 EER25178.1 - 6.9e-09 34.9 0.1 0.0012 17.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EER25178.1 - 3.8e-08 32.9 0.0 0.0049 16.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EER25178.1 - 9.2e-08 32.0 0.0 0.0063 16.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EER25178.1 - 1.6e-07 30.9 1.6 0.0047 16.6 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 EER25178.1 - 1.7e-07 30.7 0.0 4.3e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 EER25178.1 - 2.6e-07 29.9 0.0 0.0052 15.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EER25178.1 - 2.9e-07 30.0 6.1 0.026 13.9 0.0 4.8 3 2 2 5 5 4 2 AAA domain Mg_chelatase PF01078.16 EER25178.1 - 3.5e-07 29.5 0.4 0.028 13.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EER25178.1 - 1.7e-06 28.1 0.0 0.026 14.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EER25178.1 - 3.2e-06 27.4 0.0 0.067 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EER25178.1 - 4.4e-06 25.9 1.2 0.54 9.3 0.0 3.4 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 EER25178.1 - 5.2e-06 26.4 0.0 0.0055 16.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EER25178.1 - 8.1e-06 25.8 0.1 0.18 11.7 0.0 2.9 3 1 0 3 3 2 2 AAA domain DUF815 PF05673.8 EER25178.1 - 2.1e-05 23.5 0.0 0.0091 14.9 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EER25178.1 - 4.4e-05 22.8 0.4 0.22 10.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activat PF00158.21 EER25178.1 - 4.8e-05 22.9 0.1 0.46 9.9 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EER25178.1 - 5.5e-05 23.4 0.0 0.22 11.8 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.1 EER25178.1 - 6.8e-05 22.9 0.0 0.36 10.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 EER25178.1 - 6.9e-05 22.5 0.7 0.14 11.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.12 EER25178.1 - 7.9e-05 21.6 0.1 0.084 11.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Vps4_C PF09336.5 EER25178.1 - 8.5e-05 22.3 0.1 0.00041 20.1 0.0 2.2 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain Arch_ATPase PF01637.13 EER25178.1 - 0.0003 20.5 0.1 3.6 7.2 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase Bac_DnaA PF00308.13 EER25178.1 - 0.00039 20.1 0.0 1.9 8.0 0.0 3.3 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_11 PF13086.1 EER25178.1 - 0.00047 19.8 0.0 0.74 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EER25178.1 - 0.00054 19.5 0.0 1.3 8.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EER25178.1 - 0.00088 18.9 0.2 0.82 9.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EER25178.1 - 0.0013 17.7 0.0 0.59 9.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EER25178.1 - 0.0013 18.3 0.0 1.3 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EER25178.1 - 0.0027 17.4 0.4 1 9.0 0.0 3.8 4 0 0 4 4 3 1 NTPase NB-ARC PF00931.17 EER25178.1 - 0.0051 15.7 0.6 0.6 8.9 0.0 2.9 4 0 0 4 4 3 1 NB-ARC domain Viral_helicase1 PF01443.13 EER25178.1 - 0.0057 16.2 0.0 0.55 9.7 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 EER25178.1 - 0.017 14.0 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 EER25178.1 - 0.018 14.0 0.0 1.1 8.2 0.0 2.8 2 1 0 3 3 3 0 KAP family P-loop domain IPT PF01745.11 EER25178.1 - 0.024 13.7 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 EER25178.1 - 0.049 13.0 0.1 38 3.6 0.1 4.1 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EER25178.1 - 0.052 12.9 0.9 10 5.4 0.0 3.7 3 1 1 4 4 4 0 AAA-like domain SKI PF01202.17 EER25178.1 - 0.086 12.7 0.1 8.9 6.1 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 EER25178.1 - 0.13 11.9 0.1 10 5.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 EER25178.1 - 0.19 10.8 0.6 19 4.3 0.0 2.7 3 0 0 3 3 2 0 Chromatin associated protein KTI12 Adeno_PV PF03910.8 EER25179.1 - 0.0041 16.2 0.3 0.0071 15.4 0.2 1.4 1 0 0 1 1 1 1 Adenovirus minor core protein PV EnY2 PF10163.4 EER25179.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 Peptidase_S49_N PF08496.5 EER25179.1 - 0.028 14.2 4.8 0.053 13.3 3.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4611 PF15387.1 EER25179.1 - 0.093 12.8 0.3 0.093 12.8 0.2 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF4611) SOG2 PF10428.4 EER25179.1 - 0.47 9.0 11.9 0.72 8.4 8.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CDC27 PF09507.5 EER25179.1 - 0.59 9.3 34.0 0.013 14.7 17.8 1.9 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 FLO_LFY PF01698.11 EER25179.1 - 2.6 6.7 10.3 4.6 5.9 7.1 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Dicty_REP PF05086.7 EER25179.1 - 3.1 5.4 12.8 4.6 4.8 8.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box PF00646.28 EER25180.1 - 0.0077 15.8 0.5 0.062 12.9 0.0 2.6 3 0 0 3 3 3 1 F-box domain Peptidase_C98 PF15499.1 EER25180.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase F-box-like PF12937.2 EER25180.1 - 0.19 11.5 0.5 1.1 9.0 0.0 2.4 3 0 0 3 3 3 0 F-box-like RA PF00788.18 EER25181.1 - 2.8e-15 56.5 0.0 5.4e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EER25181.1 - 2.8e-13 49.5 0.0 4.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EER25181.1 - 2.3e-12 46.9 0.0 3.4e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Chorion_2 PF03964.10 EER25181.1 - 1.1 9.8 6.9 0.58 10.7 2.5 2.1 1 1 1 2 2 2 0 Chorion family 2 Cullin_binding PF03556.10 EER25182.1 - 4.1e-27 94.6 0.5 5.6e-27 94.2 0.4 1.2 1 0 0 1 1 1 1 Cullin binding AAA_10 PF12846.2 EER25183.1 - 0.037 13.4 0.4 0.053 12.9 0.3 1.2 1 0 0 1 1 1 0 AAA-like domain Zip PF02535.17 EER25183.1 - 0.11 11.4 3.7 0.14 11.0 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Cytomega_UL84 PF06284.6 EER25183.1 - 0.11 10.8 3.5 0.14 10.5 2.4 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Tim54 PF11711.3 EER25183.1 - 0.22 10.0 6.2 0.035 12.7 1.6 1.5 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3121 PF11319.3 EER25183.1 - 1.2 8.6 5.7 2.2 7.7 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) UPF0113 PF03657.8 EER25184.1 - 2.6e-07 30.4 0.0 4.4e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EER25184.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.6 EER25185.1 - 3.2e-31 107.4 0.5 3.2e-31 107.4 0.3 2.5 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 EER25185.1 - 9.4e-31 106.4 0.0 3.3e-30 104.7 0.0 1.9 1 0 0 1 1 1 1 CBF/Mak21 family DUF1349 PF07081.6 EER25188.1 - 3.1e-18 65.7 0.0 1.3e-07 31.1 0.0 2.9 2 1 0 2 2 2 2 Protein of unknown function (DUF1349) Pap_E4 PF02711.9 EER25188.1 - 0.14 12.9 4.4 0.29 11.9 3.1 1.6 1 0 0 1 1 1 0 E4 protein DUF2464 PF10240.4 EER25188.1 - 0.18 11.0 1.4 0.26 10.6 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) DUF2360 PF10152.4 EER25188.1 - 0.89 9.8 4.2 1.2 9.4 2.9 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Pex14_N PF04695.8 EER25188.1 - 0.91 9.5 7.3 1.5 8.9 5.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3446 PF11928.3 EER25188.1 - 3.1 8.0 10.6 0.13 12.5 2.8 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) PAT1 PF09770.4 EER25188.1 - 8.5 4.4 12.5 11 4.1 8.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PARG_cat PF05028.9 EER25189.1 - 6.4e-11 42.0 0.0 8.8e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Cript PF10235.4 EER25190.1 - 8.6e-37 125.3 4.6 8.6e-37 125.3 3.2 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zf-ribbon_3 PF13248.1 EER25190.1 - 0.0013 17.9 6.7 0.064 12.4 0.9 3.2 3 0 0 3 3 3 1 zinc-ribbon domain DZR PF12773.2 EER25190.1 - 0.0024 17.6 13.8 0.019 14.7 5.8 2.8 1 1 1 2 2 2 2 Double zinc ribbon eIF-4B PF06273.6 EER25190.1 - 0.0038 16.0 3.4 0.0056 15.4 2.1 1.4 1 1 0 1 1 1 1 Plant specific eukaryotic initiation factor 4B zinc_ribbon_2 PF13240.1 EER25190.1 - 0.014 14.8 8.6 0.29 10.6 0.8 3.3 2 1 1 3 3 3 0 zinc-ribbon domain zf-FCS PF06467.9 EER25190.1 - 0.075 12.6 7.2 0.87 9.2 0.1 3.1 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf-HYPF PF07503.7 EER25190.1 - 0.36 10.2 9.1 0.53 9.7 2.8 2.2 2 0 0 2 2 2 0 HypF finger DUF581 PF04570.9 EER25190.1 - 0.38 10.0 11.8 3 7.1 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF581) LIM PF00412.17 EER25190.1 - 0.66 10.0 12.2 4.3 7.4 0.1 3.3 2 1 1 3 3 3 0 LIM domain C1_1 PF00130.17 EER25190.1 - 0.84 9.4 12.5 5.6 6.7 2.4 3.1 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4pol PF14260.1 EER25190.1 - 1.9 8.5 11.3 19 5.3 4.6 2.4 2 1 1 3 3 3 0 C4-type zinc-finger of DNA polymerase delta DUF2039 PF10217.4 EER25190.1 - 3.6 7.6 18.0 5.4 7.1 8.6 2.8 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2039) zf-AD PF07776.10 EER25190.1 - 5.3 7.1 8.3 9.5 6.3 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF1272 PF06906.6 EER25190.1 - 5.4 6.9 9.9 5.4 6.9 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-FPG_IleRS PF06827.9 EER25190.1 - 6 6.6 10.7 7.4 6.3 0.2 2.9 3 1 0 3 3 3 0 Zinc finger found in FPG and IleRS MRP-L46 PF11788.3 EER25191.1 - 1.6e-32 112.4 0.2 2.8e-32 111.6 0.1 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EER25191.1 - 0.023 14.3 0.0 0.054 13.1 0.0 1.5 1 1 0 1 1 1 0 NUDIX domain CAF1 PF04857.15 EER25192.1 - 1.3e-42 145.9 0.0 1.6e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EER25192.1 - 0.02 14.3 0.0 0.4 10.1 0.0 2.5 2 0 0 2 2 2 0 3'-5' exonuclease DUF572 PF04502.8 EER25193.1 - 0.00062 19.0 15.8 0.00062 19.0 11.0 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF572) AAA_23 PF13476.1 EER25193.1 - 0.02 15.2 4.3 0.035 14.4 3.0 1.6 1 0 0 1 1 1 0 AAA domain Sipho_Gp157 PF05565.6 EER25193.1 - 0.06 12.9 9.8 0.1 12.1 6.8 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF607 PF04678.8 EER25193.1 - 0.19 11.6 3.1 0.42 10.5 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF607 FUSC PF04632.7 EER25193.1 - 0.46 8.8 3.0 0.83 8.0 2.1 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family TAF4 PF05236.9 EER25193.1 - 0.57 9.4 19.5 0.036 13.3 8.8 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Borrelia_P83 PF05262.6 EER25193.1 - 0.65 8.1 10.0 0.88 7.7 6.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein APG6 PF04111.7 EER25193.1 - 2.2 7.2 11.9 3.8 6.4 8.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 LCD1 PF09798.4 EER25193.1 - 4 5.3 11.9 5.9 4.7 8.3 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein V_ATPase_I PF01496.14 EER25193.1 - 5.8 4.6 5.8 9.7 3.8 4.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family VIT1 PF01988.14 EER25193.1 - 7.7 5.9 6.9 15 5.0 4.8 1.5 1 0 0 1 1 1 0 VIT family DUF4137 PF13593.1 EER25194.1 - 2.1e-87 293.1 14.9 2.5e-87 292.8 10.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EER25194.1 - 9.3e-12 44.7 0.7 9.3e-12 44.7 0.5 2.4 1 1 1 3 3 3 1 Sodium Bile acid symporter family Mem_trans PF03547.13 EER25194.1 - 9.5e-05 20.8 12.1 0.00091 17.6 0.4 2.4 3 0 0 3 3 3 2 Membrane transport protein Mito_carr PF00153.22 EER25195.1 - 4.8e-69 228.1 2.1 3.8e-22 77.7 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 EER25196.1 - 5.2e-17 61.9 0.0 2.4e-09 37.1 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PHF5 PF03660.9 EER25197.1 - 2.3e-51 172.3 10.3 2.6e-51 172.1 7.1 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EER25197.1 - 0.63 9.9 15.0 0.15 11.9 4.8 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EER25197.1 - 0.72 9.6 15.8 3.2 7.5 0.4 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EER25197.1 - 7.3 4.1 6.9 7.6 4.0 4.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Pinin_SDK_memA PF04696.8 EER25198.1 - 1.3e-27 95.9 13.2 1.3e-27 95.9 9.1 1.7 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Abhydrolase_6 PF12697.2 EER25199.1 - 7.4e-31 107.7 0.0 9.4e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER25199.1 - 2.6e-14 53.3 0.0 2.2e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER25199.1 - 8.3e-12 45.0 0.0 3e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EER25199.1 - 0.00073 19.3 0.0 0.003 17.3 0.0 2.0 2 1 1 3 3 3 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EER25199.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Saccharop_dh PF03435.13 EER25200.1 - 1.5e-22 80.1 0.0 2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EER25200.1 - 0.018 15.3 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EER25200.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ribosomal_L37ae PF01780.14 EER25201.1 - 1.5e-40 136.9 9.9 1.6e-40 136.8 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EER25201.1 - 0.0068 16.1 2.9 0.01 15.6 2.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EER25201.1 - 0.021 14.5 3.8 0.32 10.7 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger GCC2_GCC3 PF07699.8 EER25201.1 - 0.03 13.9 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 OrfB_Zn_ribbon PF07282.6 EER25201.1 - 0.12 12.0 0.9 0.16 11.6 0.6 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain C1_1 PF00130.17 EER25201.1 - 0.19 11.4 1.9 0.27 10.9 1.3 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 EER25201.1 - 0.25 10.8 3.2 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Tnp_zf-ribbon_2 PF13842.1 EER25201.1 - 0.3 11.5 2.6 0.75 10.2 1.8 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon NOB1_Zn_bind PF08772.6 EER25201.1 - 0.31 10.9 3.8 2.4 8.0 2.6 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Elf1 PF05129.8 EER25201.1 - 0.35 10.5 3.2 0.6 9.8 2.2 1.4 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.10 EER25201.1 - 3 7.4 5.2 2.3 7.8 0.1 2.1 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger PHD PF00628.24 EER25202.1 - 1.4e-08 34.2 9.3 1.4e-08 34.2 6.4 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EER25202.1 - 1.5e-08 34.2 2.2 1.5e-08 34.2 1.5 3.7 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EER25202.1 - 1.9e-06 27.4 1.0 1.9e-06 27.4 0.7 3.2 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER25202.1 - 4.4e-06 26.3 5.6 6e-06 25.8 0.5 2.9 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EER25202.1 - 5.8e-06 25.8 0.6 5.8e-06 25.8 0.4 2.9 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER25202.1 - 6.4e-06 26.1 1.6 6.4e-06 26.1 1.1 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EER25202.1 - 3.2e-05 23.9 4.0 3.2e-05 23.9 2.8 2.5 2 1 0 2 2 2 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EER25202.1 - 0.0003 20.5 0.3 0.0003 20.5 0.2 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD_2 PF13831.1 EER25202.1 - 0.00045 19.4 4.6 0.00094 18.4 3.2 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_4 PF14447.1 EER25202.1 - 0.012 15.0 3.5 0.038 13.5 0.6 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-PHD-like PF15446.1 EER25202.1 - 0.043 13.0 3.1 0.046 13.0 0.2 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-Di19 PF05605.7 EER25202.1 - 0.14 12.3 6.1 0.28 11.3 0.0 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_4 PF14570.1 EER25202.1 - 0.19 11.3 5.2 0.061 12.9 0.7 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C2HC_2 PF13913.1 EER25202.1 - 0.4 10.3 0.1 0.4 10.3 0.0 3.3 3 0 0 3 3 2 0 zinc-finger of a C2HC-type DZR PF12773.2 EER25202.1 - 9.2 6.1 10.4 3.8e+02 0.9 7.2 2.8 1 1 0 1 1 1 0 Double zinc ribbon MFS_1 PF07690.11 EER25203.1 - 7.3e-36 123.6 52.5 2e-34 118.8 34.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER25203.1 - 2.9e-10 39.3 34.5 1.6e-08 33.5 23.9 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter DUF1673 PF07895.6 EER25203.1 - 0.0057 16.2 0.6 0.0057 16.2 0.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1673) HEAT_2 PF13646.1 EER25204.1 - 8.3e-07 29.2 3.3 1.4e-05 25.2 0.4 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EER25204.1 - 6.7e-06 25.7 2.5 0.12 12.5 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EER25204.1 - 5e-05 23.6 5.0 0.0021 18.4 0.1 4.6 3 0 0 3 3 3 1 HEAT-like repeat CLASP_N PF12348.3 EER25204.1 - 0.0033 16.8 0.1 0.53 9.5 0.0 3.2 3 0 0 3 3 3 1 CLASP N terminal PHD PF00628.24 EER25206.1 - 6.9e-14 51.2 21.1 4.3e-11 42.3 4.3 3.0 2 1 1 3 3 3 3 PHD-finger C1_1 PF00130.17 EER25206.1 - 0.0046 16.6 2.6 0.0046 16.6 1.8 2.9 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 EER25206.1 - 0.25 10.5 10.5 1.2 8.4 1.2 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-RING-like PF08746.6 EER25206.1 - 3 7.9 15.1 0.08 12.9 2.5 2.6 2 0 0 2 2 2 0 RING-like domain Peptidase_M24 PF00557.19 EER25207.1 - 2.8e-12 46.6 0.0 3.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.18 EER25208.1 - 2e-12 47.6 0.1 2.4e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNF5 PF04855.7 EER25209.1 - 8.8e-75 251.3 0.0 1.4e-74 250.6 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 PI3K_1B_p101 PF10486.4 EER25209.1 - 0.1 10.1 0.1 0.15 9.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Lectin_leg-like PF03388.8 EER25210.1 - 3.8e-28 98.1 0.0 6.3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family NPV_P10 PF05531.7 EER25210.1 - 0.031 14.5 3.8 4.4 7.6 0.2 2.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EER25210.1 - 0.041 13.4 9.0 0.081 12.5 6.2 1.4 1 0 0 1 1 1 0 IncA protein DUF3573 PF12097.3 EER25210.1 - 0.27 9.7 1.7 0.49 8.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Alg6_Alg8 PF03155.10 EER25211.1 - 1e-136 456.5 28.4 1.3e-136 456.2 19.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 EER25212.1 - 2.3e-24 85.4 1.9 6.8e-23 80.7 0.0 3.5 2 1 1 3 3 3 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EER25212.1 - 2.9e-18 65.3 1.6 5.5e-18 64.5 1.1 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EER25212.1 - 1.4e-12 47.0 0.5 3.2e-12 45.8 0.4 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EER25212.1 - 7.8e-06 25.5 0.4 7.8e-06 25.5 0.3 1.9 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EER25212.1 - 0.00038 20.2 0.1 0.0014 18.4 0.1 2.1 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Mito_carr PF00153.22 EER25213.1 - 5.7e-60 199.0 3.7 6.5e-21 73.8 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2360 PF10152.4 EER25213.1 - 5.2 7.3 5.0 0.98 9.6 0.7 1.8 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pex2_Pex12 PF04757.9 EER25214.1 - 1e-56 191.9 3.1 1.3e-56 191.6 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EER25214.1 - 6.2e-07 29.1 2.8 1.1e-06 28.3 1.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EER25214.1 - 1.1e-06 28.5 4.2 1.9e-06 27.7 2.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER25214.1 - 8.1e-05 22.3 3.1 0.00011 21.9 1.5 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EER25214.1 - 0.0019 17.8 1.9 0.0033 17.0 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER25214.1 - 0.042 13.5 1.7 0.081 12.6 1.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Oligomerisation PF02410.10 EER25215.1 - 3.5e-06 26.9 0.0 4.1e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Oligomerisation domain PPR_3 PF13812.1 EER25215.1 - 0.029 14.6 0.4 27 5.3 0.0 3.8 3 0 0 3 3 3 0 Pentatricopeptide repeat domain NMD3 PF04981.8 EER25216.1 - 3.3e-76 255.5 3.4 4.4e-76 255.0 2.3 1.2 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.16 EER25216.1 - 0.39 10.6 6.3 1.5 8.8 2.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger HypA PF01155.14 EER25216.1 - 0.71 9.5 6.2 5.5 6.7 0.8 2.7 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EER25216.1 - 0.86 9.4 9.0 11 5.9 4.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_6 PF14599.1 EER25216.1 - 7.6 6.4 12.9 14 5.5 0.2 4.1 3 1 2 5 5 5 0 Zinc-ribbon RRM_1 PF00076.17 EER25217.1 - 0.086 12.4 0.0 0.41 10.3 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25217.1 - 0.1 12.4 0.0 0.31 10.9 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Menin PF05053.8 EER25217.1 - 5.8 4.9 12.9 0.023 12.8 2.8 1.4 2 0 0 2 2 2 0 Menin DUF1237 PF06824.6 EER25218.1 - 2.2e-182 606.3 0.0 2.6e-182 606.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Rhodopsin_N PF10413.4 EER25218.1 - 0.066 12.9 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin CDC27 PF09507.5 EER25219.1 - 3.6e-97 326.3 26.8 4.1e-97 326.1 18.6 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-C3HC4_2 PF13923.1 EER25220.1 - 1.4e-07 31.4 24.8 3e-07 30.3 12.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EER25220.1 - 3.2e-07 30.0 7.5 6.6e-07 29.0 5.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EER25220.1 - 4e-06 26.5 20.5 1.2e-05 25.0 11.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EER25220.1 - 7.6e-06 25.5 13.9 7.6e-06 25.5 9.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER25220.1 - 8.7e-06 25.2 17.5 8.7e-06 25.2 12.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER25220.1 - 2.5e-05 23.9 16.9 2.5e-05 23.9 11.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EER25220.1 - 0.00032 20.5 16.2 0.00032 20.5 11.2 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING SAP PF02037.22 EER25220.1 - 0.0013 18.1 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain Sgf11 PF08209.6 EER25220.1 - 0.0069 15.6 0.2 0.0069 15.6 0.1 2.2 2 1 0 2 2 2 1 Sgf11 (transcriptional regulation protein) U-box PF04564.10 EER25220.1 - 0.02 14.8 0.0 0.064 13.2 0.0 1.8 1 0 0 1 1 1 0 U-box domain Mob_synth_C PF06463.8 EER25220.1 - 0.044 13.4 3.7 0.12 12.0 2.6 1.7 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C zf-RING_UBOX PF13445.1 EER25220.1 - 0.064 12.9 20.3 0.056 13.1 8.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger DUF1178 PF06676.6 EER25220.1 - 0.074 13.2 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) zf-rbx1 PF12678.2 EER25220.1 - 0.14 12.2 10.9 0.4 10.8 5.8 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger zf-Nse PF11789.3 EER25220.1 - 8.4 6.0 12.5 3 7.4 6.2 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Snf7 PF03357.16 EER25221.1 - 3.2e-16 59.1 14.9 3.2e-16 59.1 10.3 1.7 1 1 0 1 1 1 1 Snf7 AAA_24 PF13479.1 EER25221.1 - 0.067 12.7 0.3 0.18 11.3 0.3 1.6 1 1 0 1 1 1 0 AAA domain YhhN PF07947.9 EER25222.1 - 9.4e-43 145.7 5.7 1.4e-42 145.1 4.0 1.3 1 0 0 1 1 1 1 YhhN-like protein NfeD PF01957.13 EER25222.1 - 0.23 11.5 9.6 7.2 6.7 0.7 3.3 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding Pox_A14 PF05767.7 EER25222.1 - 1.7 8.6 6.5 9.3 6.2 0.1 2.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 TRAPPC-Trs85 PF12739.2 EER25223.1 - 3.6e-126 421.1 0.2 5.5e-124 413.9 0.1 2.1 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit PolyA_pol PF01743.15 EER25224.1 - 4.4e-21 75.3 0.1 2e-20 73.2 0.1 2.2 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EER25224.1 - 6.7e-07 28.7 0.0 2.4e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EER25224.1 - 0.0013 18.5 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF2454 PF10521.4 EER25225.1 - 1.1e-87 293.6 2.5 1.4e-87 293.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Xpo1 PF08389.7 EER25225.1 - 0.23 11.3 2.5 1.6 8.6 0.1 3.0 3 1 0 3 3 3 0 Exportin 1-like protein Syja_N PF02383.13 EER25226.1 - 6.3e-95 317.5 0.2 1e-94 316.8 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Glyco_hydro_47 PF01532.15 EER25227.1 - 1.1e-175 584.6 0.0 1.3e-175 584.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ADH_zinc_N PF00107.21 EER25228.1 - 2.7e-19 68.9 1.8 4.5e-19 68.2 0.8 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER25228.1 - 6.2e-10 38.8 1.5 3.9e-09 36.2 0.0 2.9 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EER25228.1 - 8.9e-10 39.5 0.1 1.6e-09 38.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TPR_7 PF13176.1 EER25229.1 - 2.4e-06 26.8 1.2 5.2 7.1 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EER25229.1 - 2.5e-06 27.3 4.5 0.012 15.5 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EER25229.1 - 8.6e-06 25.9 5.9 1.6 9.6 0.3 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER25229.1 - 2.7e-05 24.4 3.6 4.7 7.6 0.2 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EER25229.1 - 7.3e-05 22.3 0.0 1.8 8.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EER25229.1 - 0.00025 20.6 1.3 2.4 7.8 0.0 3.9 2 1 3 5 5 5 3 TPR repeat TPR_16 PF13432.1 EER25229.1 - 0.0021 18.7 2.3 4.3 8.1 0.0 4.3 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EER25229.1 - 0.0025 18.0 0.1 17 6.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EER25229.1 - 0.015 15.1 2.8 3.1 7.8 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EER25229.1 - 0.077 12.6 0.0 4.7 6.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Mur_ligase_M PF08245.7 EER25230.1 - 0.00011 22.3 0.1 0.002 18.2 0.0 2.3 1 1 0 1 1 1 1 Mur ligase middle domain EAF PF09816.4 EER25230.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription elongation factor TPR_12 PF13424.1 EER25231.1 - 1.2e-11 44.3 0.1 7.3e-05 22.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EER25231.1 - 5.8e-09 36.1 0.3 0.084 13.2 0.0 6.0 4 1 3 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EER25231.1 - 3.8e-08 33.2 3.0 0.78 10.5 0.0 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat DUF676 PF05057.9 EER25231.1 - 3e-07 29.9 0.0 7.6e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_2 PF07719.12 EER25231.1 - 9.3e-07 28.3 0.0 0.025 14.4 0.0 5.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EER25231.1 - 6.8e-06 25.6 0.0 0.29 10.7 0.0 3.3 2 1 2 4 4 4 3 TPR repeat TPR_7 PF13176.1 EER25231.1 - 8.2e-06 25.2 0.3 0.085 12.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat NB-ARC PF00931.17 EER25231.1 - 1.7e-05 23.8 0.0 3.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 EER25231.1 - 4.2e-05 24.1 0.0 5.7 7.7 0.0 4.5 3 1 1 4 4 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 EER25231.1 - 0.00022 21.3 0.0 0.00078 19.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain TPR_10 PF13374.1 EER25231.1 - 0.00025 20.8 0.2 1.5 8.8 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EER25231.1 - 0.0011 19.2 1.3 13 6.6 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat PGAP1 PF07819.8 EER25231.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein PPR PF01535.15 EER25231.1 - 0.0014 18.5 0.0 5.8 7.1 0.0 3.8 3 0 0 3 3 3 1 PPR repeat TPR_8 PF13181.1 EER25231.1 - 0.0055 16.4 0.3 0.17 11.7 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER25231.1 - 0.006 16.1 0.1 1.6 8.4 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EER25231.1 - 0.0093 15.8 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_6 PF13174.1 EER25231.1 - 0.022 15.1 1.0 1.6 9.3 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Zot PF05707.7 EER25231.1 - 0.047 13.1 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) TPR_17 PF13431.1 EER25231.1 - 0.12 12.6 0.0 43 4.6 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat FYVE PF01363.16 EER25232.1 - 0.00055 19.7 0.3 0.0011 18.7 0.2 1.6 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_1 PF14446.1 EER25232.1 - 0.12 12.1 2.8 0.24 11.1 2.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 DZR PF12773.2 EER25232.1 - 0.13 12.1 5.8 0.11 12.3 2.8 1.8 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 EER25232.1 - 0.2 11.2 3.5 1.7 8.2 2.3 2.4 1 1 1 2 2 2 0 zinc-ribbon domain IBR PF01485.16 EER25232.1 - 0.27 11.1 3.5 0.73 9.7 2.5 1.7 1 0 0 1 1 1 0 IBR domain HypA PF01155.14 EER25232.1 - 0.4 10.3 4.9 0.6 9.8 2.4 1.9 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_4 PF13717.1 EER25232.1 - 0.46 10.2 3.9 5.4 6.7 0.2 2.5 1 1 1 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 EER25233.1 - 2e-33 115.6 0.0 1.3e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER25233.1 - 1.1e-14 54.1 0.0 4.7e-06 25.8 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Zn_clus PF00172.13 EER25234.1 - 4.3e-10 39.3 8.5 7.8e-10 38.5 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EER25234.1 - 5.4e-10 38.4 2.4 5.4e-10 38.4 1.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Tyrosinase PF00264.15 EER25235.1 - 3.1e-39 135.4 6.5 4.3e-39 134.9 4.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase YtxH PF12732.2 EER25235.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 YtxH-like protein DNA_pol_B PF00136.16 EER25236.1 - 2.1e-147 491.7 4.6 2.9e-147 491.2 3.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EER25236.1 - 1.9e-81 273.4 0.1 3.8e-81 272.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EER25236.1 - 1.3e-23 82.7 6.4 1.3e-23 82.7 4.4 2.0 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EER25236.1 - 4.8e-05 23.2 0.2 0.00027 20.7 0.1 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EER25236.1 - 0.00021 20.8 0.1 0.00042 19.9 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB PAS_4 PF08448.5 EER25238.1 - 0.03 14.3 0.4 0.051 13.6 0.2 1.3 1 0 0 1 1 1 0 PAS fold zf-C2H2_4 PF13894.1 EER25239.1 - 9.4e-10 38.1 6.7 0.083 13.2 0.0 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EER25239.1 - 1.6e-08 34.4 17.5 0.062 13.6 1.0 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EER25239.1 - 0.0016 18.2 9.9 2.2 8.3 0.1 4.9 5 0 0 5 5 5 2 C2H2-type zinc finger zf-met PF12874.2 EER25239.1 - 0.0053 16.9 2.9 33 4.8 0.2 4.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Rad50_zn_hook PF04423.9 EER25239.1 - 0.0053 16.1 1.2 0.027 13.9 0.1 2.7 2 1 0 2 2 2 1 Rad50 zinc hook motif zf-C2H2_2 PF12756.2 EER25239.1 - 0.015 15.3 8.9 4.2 7.5 1.0 3.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Cytochrom_CIII PF02085.11 EER25239.1 - 0.023 14.7 9.7 0.045 13.8 6.8 1.5 1 0 0 1 1 1 0 Class III cytochrome C family zf-C2H2_jaz PF12171.3 EER25239.1 - 0.1 12.8 12.5 4.8 7.4 0.0 5.2 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding DZR PF12773.2 EER25239.1 - 0.15 11.9 6.9 1.9 8.3 3.5 2.4 1 1 1 2 2 2 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 EER25239.1 - 0.16 12.0 5.1 3.2 7.9 0.1 3.4 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-H2C2_2 PF13465.1 EER25239.1 - 0.32 11.3 14.2 9.7 6.6 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger double domain zinc-ribbons_6 PF07191.7 EER25239.1 - 0.34 10.7 2.6 5.5 6.8 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbons zf-RING_3 PF14369.1 EER25239.1 - 0.44 10.5 5.3 6.4 6.8 0.2 3.3 3 0 0 3 3 3 0 zinc-finger Zn-ribbon_8 PF09723.5 EER25239.1 - 1.3 9.0 6.5 5 7.1 1.7 2.8 2 1 0 2 2 2 0 Zinc ribbon domain Cyanate_lyase PF02560.9 EER25240.1 - 5e-28 96.4 0.0 6.9e-28 95.9 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain AP_endonuc_2 PF01261.19 EER25241.1 - 1.5e-33 115.8 0.0 2.6e-33 115.1 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Pentapeptide_4 PF13599.1 EER25242.1 - 1.1e-10 41.1 0.9 0.00057 19.6 0.0 3.2 2 1 1 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EER25242.1 - 0.00071 19.4 0.7 3.9 7.4 0.0 4.3 2 2 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 EER25242.1 - 0.0019 17.3 0.0 0.32 10.2 0.0 2.7 3 0 0 3 3 3 2 Pentapeptide repeats (8 copies) PLDc_2 PF13091.1 EER25243.1 - 4.1e-13 49.1 0.1 5.7e-06 26.0 0.0 3.2 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EER25243.1 - 8.9e-12 44.4 2.0 3.5e-06 26.6 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif DUF3317 PF11779.3 EER25244.1 - 3.6e-19 67.9 4.1 7e-19 67.0 2.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) PAP2 PF01569.16 EER25244.1 - 0.087 12.5 0.2 0.16 11.6 0.1 1.4 1 1 0 1 1 1 0 PAP2 superfamily Kinetochor_Ybp2 PF08568.5 EER25245.1 - 1.1e-120 403.8 0.0 1.2e-120 403.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Rhomboid PF01694.17 EER25247.1 - 1.2e-35 122.7 11.4 1.2e-35 122.7 7.9 2.4 3 0 0 3 3 3 1 Rhomboid family DUF4203 PF13886.1 EER25247.1 - 0.038 13.4 12.4 0.29 10.5 4.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) GST_N_3 PF13417.1 EER25248.1 - 6.1e-06 26.3 0.1 1.7e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EER25248.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EER25248.1 - 0.0017 18.3 0.2 0.0054 16.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER25248.1 - 0.0029 17.4 0.0 0.0067 16.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EER25248.1 - 0.0038 17.6 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-DHHC PF01529.15 EER25249.1 - 5.7e-42 143.0 5.6 5.7e-42 143.0 3.9 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EER25249.1 - 0.053 13.3 3.5 3.6 7.3 0.9 2.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily Sensor PF13796.1 EER25249.1 - 0.23 11.0 6.5 0.71 9.4 3.4 2.2 2 0 0 2 2 2 0 Putative sensor UQ_con PF00179.21 EER25250.1 - 2.1e-21 75.8 0.0 3e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Adeno_E3 PF06040.6 EER25250.1 - 0.0084 16.0 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Adenovirus E3 protein RWD PF05773.17 EER25250.1 - 0.036 13.9 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 RWD domain DUF1180 PF06679.7 EER25250.1 - 0.068 13.0 1.5 0.12 12.3 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RNase_PH PF01138.16 EER25250.1 - 0.076 13.3 0.3 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 RRM_1 PF00076.17 EER25251.1 - 1.3e-14 53.5 0.3 3.5e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER25251.1 - 2.8e-13 49.6 0.0 4.4e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25251.1 - 2.2e-06 27.4 0.3 3.6e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SR-25 PF10500.4 EER25251.1 - 0.023 14.1 12.1 0.042 13.3 8.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF2514 PF10721.4 EER25251.1 - 0.22 11.2 15.1 0.36 10.5 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Metaviral_G PF09595.5 EER25251.1 - 0.5 9.9 9.0 0.26 10.9 1.7 2.1 2 0 0 2 2 2 0 Metaviral_G glycoprotein Ycf1 PF05758.7 EER25251.1 - 0.7 7.5 5.2 0.86 7.2 3.6 1.0 1 0 0 1 1 1 0 Ycf1 VIT1 PF01988.14 EER25251.1 - 1.6 8.1 7.1 2.3 7.6 4.9 1.1 1 0 0 1 1 1 0 VIT family MCLC PF05934.6 EER25251.1 - 2.8 6.1 5.8 4.4 5.4 4.0 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Fmp27 PF10344.4 EER25254.1 - 3.3e-196 653.7 0.0 1.1e-195 651.9 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EER25254.1 - 3.5e-169 563.4 0.3 3.5e-169 563.4 0.2 1.9 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EER25254.1 - 1.9e-152 508.0 0.4 1.9e-152 508.0 0.3 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EER25254.1 - 1.1e-55 187.6 0.7 2.5e-55 186.5 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 EER25254.1 - 2.1e-52 177.1 0.0 4.5e-52 176.0 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 EER25254.1 - 4.2e-29 101.0 0.0 1.4e-28 99.3 0.0 2.0 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain B-block_TFIIIC PF04182.7 EER25256.1 - 5.3e-20 71.0 0.1 1.3e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.17 EER25256.1 - 0.0097 15.5 0.4 0.17 11.6 0.0 2.7 2 0 0 2 2 2 1 MarR family MarR_2 PF12802.2 EER25256.1 - 0.011 15.3 0.4 0.087 12.5 0.0 2.7 2 0 0 2 2 2 0 MarR family tRNA-synt_1c PF00749.16 EER25257.1 - 1.1e-94 316.6 0.0 1.6e-94 316.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain CTDII PF01556.13 EER25258.1 - 4.5e-24 84.1 0.0 8.1e-20 70.5 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EER25258.1 - 5.9e-21 73.9 1.8 1.2e-20 72.9 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EER25258.1 - 2.8e-13 49.7 16.8 4.7e-13 48.9 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain YcfA PF07927.7 EER25258.1 - 0.0029 17.4 0.0 0.0085 15.9 0.0 1.8 1 0 0 1 1 1 1 YcfA-like protein HypA PF01155.14 EER25258.1 - 0.055 13.1 6.8 0.19 11.4 0.9 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family GCC2_GCC3 PF07699.8 EER25258.1 - 3.6 7.2 10.2 6.7 6.3 1.0 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 4HBT PF03061.17 EER25259.1 - 4.2e-10 39.5 0.0 7.5e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EER25259.1 - 3.2e-05 23.0 0.1 4.5e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase 4HBT_2 PF13279.1 EER25259.1 - 0.00013 22.4 0.0 0.00017 22.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily PseudoU_synth_2 PF00849.17 EER25260.1 - 2.1e-26 92.7 0.0 3.4e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.20 EER25260.1 - 0.0013 18.1 0.1 0.0028 17.0 0.1 1.5 1 0 0 1 1 1 1 S4 domain Auto_anti-p27 PF06677.7 EER25260.1 - 0.097 12.4 0.2 0.19 11.5 0.1 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ribosomal_L32e PF01655.13 EER25261.1 - 6.9e-48 161.2 1.0 6.9e-48 161.2 0.7 1.3 2 0 0 2 2 2 1 Ribosomal protein L32 Gp_UL130 PF11668.3 EER25261.1 - 0.077 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 Sec2p PF06428.6 EER25262.1 - 3.5e-10 39.6 9.7 3.5e-10 39.6 6.7 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p PspA_IM30 PF04012.7 EER25262.1 - 0.00011 21.6 15.5 0.00015 21.2 0.1 2.1 2 0 0 2 2 2 1 PspA/IM30 family ATG16 PF08614.6 EER25262.1 - 0.00016 21.5 13.8 0.0033 17.2 4.5 2.2 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) IncA PF04156.9 EER25262.1 - 0.00018 21.1 12.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 2 IncA protein CDC37_N PF03234.9 EER25262.1 - 0.017 15.4 1.9 0.51 10.6 1.0 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding HSBP1 PF06825.7 EER25262.1 - 0.02 14.4 0.9 0.23 11.0 0.3 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Med4 PF10018.4 EER25262.1 - 0.02 14.2 0.0 0.02 14.2 0.0 2.6 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 GOLGA2L5 PF15070.1 EER25262.1 - 0.026 13.0 6.4 0.039 12.4 0.0 2.2 2 0 0 2 2 2 0 Putative golgin subfamily A member 2-like protein 5 Laminin_II PF06009.7 EER25262.1 - 0.074 12.8 7.7 0.44 10.3 1.7 2.2 2 0 0 2 2 2 0 Laminin Domain II Atg14 PF10186.4 EER25262.1 - 0.08 11.8 13.3 3.8 6.3 0.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EER25262.1 - 0.085 13.2 13.1 0.28 11.5 0.5 3.6 2 2 1 3 3 3 0 SlyX Jnk-SapK_ap_N PF09744.4 EER25262.1 - 0.089 12.7 12.6 2.7 7.9 5.4 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 AAA_13 PF13166.1 EER25262.1 - 0.15 10.4 6.4 0.81 8.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain FliD_C PF07195.7 EER25262.1 - 0.46 9.7 5.0 3.4 6.9 0.2 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Fib_alpha PF08702.5 EER25262.1 - 0.47 10.5 4.4 9.4 6.3 0.1 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family LXG PF04740.7 EER25262.1 - 0.49 10.1 5.2 0.11 12.2 0.5 1.9 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF4407 PF14362.1 EER25262.1 - 0.57 9.0 10.7 3 6.6 4.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nsp1_C PF05064.8 EER25262.1 - 0.57 9.8 7.8 1.3 8.7 0.4 2.7 2 1 0 2 2 2 0 Nsp1-like C-terminal region DUF3584 PF12128.3 EER25262.1 - 0.95 6.7 16.7 1.2 6.3 5.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Lzipper-MIP1 PF14389.1 EER25262.1 - 1.3 9.2 12.3 4.7 7.3 5.5 3.2 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 AAA_27 PF13514.1 EER25262.1 - 1.3 6.6 18.7 0.52 7.9 0.5 2.0 2 0 0 2 2 2 0 AAA domain Myosin_tail_1 PF01576.14 EER25262.1 - 1.3 6.6 22.1 0.7 7.5 10.0 2.0 2 0 0 2 2 2 0 Myosin tail Miff PF05644.6 EER25262.1 - 1.6 8.3 9.0 1.7 8.2 5.6 1.4 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff CAF-1_p150 PF11600.3 EER25262.1 - 3.8 6.8 13.7 0.28 10.5 5.9 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 EER25262.1 - 4 6.3 10.4 13 4.6 3.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 HAUS6_N PF14661.1 EER25262.1 - 5.5 6.2 12.5 0.24 10.7 3.4 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus HR1 PF02185.11 EER25262.1 - 5.8 6.7 14.2 14 5.4 4.9 3.2 2 2 1 3 3 3 0 Hr1 repeat GAS PF13851.1 EER25262.1 - 8.9 5.4 14.2 3.8 6.6 0.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MAP65_ASE1 PF03999.7 EER25263.1 - 1.3e-76 258.5 1.9 1.6e-74 251.6 0.1 2.2 1 1 1 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF948 PF06103.6 EER25263.1 - 0.026 14.3 1.7 0.69 9.8 0.1 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.16 EER25263.1 - 2.1 8.6 8.8 4.2 7.6 0.1 4.2 4 0 0 4 4 4 0 Spectrin repeat JAB PF01398.16 EER25264.1 - 1.8e-27 95.3 0.6 2.5e-27 94.8 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EER25264.1 - 4.5e-07 29.4 0.0 1.1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CRCB PF02537.10 EER25266.1 - 5.2e-33 113.3 19.1 4.6e-19 68.4 7.1 3.5 3 0 0 3 3 3 3 CrcB-like protein Caldesmon PF02029.10 EER25266.1 - 0.0078 14.6 4.8 0.012 14.0 3.3 1.2 1 0 0 1 1 1 1 Caldesmon UPRTase PF14681.1 EER25267.1 - 7.3e-74 247.4 0.0 8.3e-74 247.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EER25267.1 - 6e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain P5CR_dimer PF14748.1 EER25267.1 - 0.056 13.4 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation TMP-TENI PF02581.12 EER25267.1 - 0.06 12.4 0.1 0.22 10.5 0.0 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Fungal_trans PF04082.13 EER25268.1 - 1.7e-17 63.1 2.2 2.8e-17 62.4 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EER25268.1 - 3.6e-07 30.1 13.4 0.00011 22.3 4.0 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER25268.1 - 6.1e-05 23.0 13.3 0.0042 17.3 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EER25268.1 - 0.00022 21.3 14.4 0.036 14.4 4.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type TPPII_N PF12583.3 EER25268.1 - 0.29 11.2 3.9 0.62 10.2 2.7 1.5 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal RasGEF PF00617.14 EER25269.1 - 1.7e-63 213.7 0.1 2.7e-63 213.0 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EER25269.1 - 3.5e-27 94.5 0.3 1e-26 93.0 0.2 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EER25269.1 - 3.9e-15 54.9 0.2 9.6e-15 53.7 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EER25269.1 - 1.4e-12 46.9 0.2 3e-12 45.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EER25269.1 - 1.1e-10 40.8 0.1 2.3e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EER25269.1 - 0.00089 19.0 0.0 0.0025 17.6 0.0 1.8 1 0 0 1 1 1 1 WW domain Peptidase_S28 PF05577.7 EER25270.1 - 2.9e-52 177.7 3.5 1.1e-50 172.4 3.3 2.5 2 1 0 2 2 2 1 Serine carboxypeptidase S28 FAD_binding_4 PF01565.18 EER25271.1 - 2e-18 66.2 0.0 3.2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain RNA_pol_Rpc4 PF05132.9 EER25273.1 - 1.1e-28 99.7 0.0 1.1e-28 99.7 0.0 3.4 4 1 0 4 4 4 1 RNA polymerase III RPC4 Zn_clus PF00172.13 EER25274.1 - 0.0011 18.7 12.7 0.0022 17.8 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.18 EER25275.1 - 1.2e-43 147.6 0.3 2.2e-43 146.8 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EER25275.1 - 1.7e-32 111.8 0.1 3.8e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DcpS_C PF11969.3 EER25276.1 - 4.1e-19 68.9 1.4 1.9e-18 66.7 1.0 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EER25276.1 - 2.4e-14 53.6 3.0 1.1e-13 51.5 2.1 1.9 1 1 0 1 1 1 1 HIT domain OB_NTP_bind PF07717.11 EER25277.1 - 2.8e-17 62.5 0.0 6.1e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EER25277.1 - 1e-16 60.7 0.4 2.8e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EER25277.1 - 2.3e-13 49.8 0.0 6.4e-13 48.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EER25277.1 - 8.7e-11 41.7 0.8 1.8e-10 40.7 0.6 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EER25277.1 - 1.1e-07 31.4 0.2 2.1e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EER25277.1 - 0.00083 18.3 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein UBA PF00627.26 EER25277.1 - 0.0078 16.0 1.1 0.25 11.2 0.1 2.6 2 0 0 2 2 2 1 UBA/TS-N domain CoA_trans PF01144.18 EER25277.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Coenzyme A transferase DND1_DSRM PF14709.1 EER25277.1 - 0.014 15.7 0.3 0.041 14.1 0.2 1.9 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_29 PF13555.1 EER25277.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EER25277.1 - 0.019 15.1 0.1 0.062 13.4 0.1 1.9 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EER25277.1 - 0.019 14.0 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EER25277.1 - 0.035 13.3 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EER25277.1 - 0.36 11.1 2.0 0.46 10.7 0.4 1.9 2 0 0 2 2 2 0 AAA domain HATPase_c PF02518.21 EER25278.1 - 7.6e-18 64.2 0.0 1.4e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EER25278.1 - 4.9e-13 49.0 0.1 0.00033 20.6 0.0 3.5 3 0 0 3 3 3 3 Response regulator receiver domain HisKA PF00512.20 EER25278.1 - 8.1e-06 25.7 0.1 2.3e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Ribosomal_L36e PF01158.13 EER25279.1 - 3.3e-40 136.0 6.9 3.7e-40 135.8 4.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF1932 PF09130.6 EER25279.1 - 0.049 13.3 0.2 0.079 12.7 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1932) PBS_linker_poly PF00427.16 EER25279.1 - 0.13 11.8 0.3 0.15 11.7 0.2 1.1 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide MRP-L28 PF09812.4 EER25279.1 - 0.44 10.3 2.6 0.44 10.3 1.4 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L28 TUG-UBL1 PF11470.3 EER25280.1 - 3e-24 84.6 0.0 8.5e-24 83.2 0.0 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EER25280.1 - 2.3e-06 27.5 0.0 2.8e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 UBX domain RBD PF02196.10 EER25280.1 - 0.049 13.3 0.1 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Raf-like Ras-binding domain Proteasome PF00227.21 EER25281.1 - 3.8e-39 133.9 0.0 4.4e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NatB_MDM20 PF09797.4 EER25282.1 - 1.7e-90 303.3 0.8 3.2e-90 302.4 0.6 1.5 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EER25282.1 - 9.1e-07 29.1 8.7 0.011 16.0 0.2 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER25282.1 - 0.0032 18.0 4.6 1.7 9.3 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EER25282.1 - 0.0068 16.9 6.4 42 5.1 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TraK PF06586.6 EER25282.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 TraK protein 2OG-Fe_Oxy_2 PF10014.4 EER25283.1 - 0.041 13.2 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 2OG-Fe dioxygenase Methyltransf_2 PF00891.13 EER25285.1 - 3.5e-33 114.8 0.2 2.3e-32 112.0 0.1 2.0 1 1 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 EER25285.1 - 0.00012 21.7 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 MarR family Dimerisation PF08100.6 EER25285.1 - 0.00016 21.4 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain HTH_27 PF13463.1 EER25285.1 - 0.00021 21.5 0.0 0.00086 19.5 0.0 2.0 2 0 0 2 2 2 1 Winged helix DNA-binding domain HTH_5 PF01022.15 EER25285.1 - 0.0014 18.2 0.0 0.0032 17.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family Rrf2 PF02082.15 EER25285.1 - 0.018 15.1 0.0 0.13 12.3 0.0 2.3 3 0 0 3 3 3 0 Transcriptional regulator HTH_24 PF13412.1 EER25285.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR PF01047.17 EER25285.1 - 0.028 14.1 0.0 0.074 12.7 0.0 1.7 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.5 EER25285.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain AT_hook PF02178.14 EER25285.1 - 0.29 10.9 2.8 0.97 9.3 2.0 1.9 1 0 0 1 1 1 0 AT hook motif zf-RING_2 PF13639.1 EER25286.1 - 1e-06 28.4 8.3 1e-06 28.4 5.8 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EER25286.1 - 5.2e-05 22.8 6.0 5.2e-05 22.8 4.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER25286.1 - 0.00012 22.0 7.4 0.00012 22.0 5.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EER25286.1 - 0.00016 21.4 7.6 0.00016 21.4 5.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EER25286.1 - 0.00022 20.8 6.8 0.00022 20.8 4.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EER25286.1 - 0.00076 19.1 3.6 0.00076 19.1 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EER25286.1 - 0.034 13.8 2.7 0.077 12.7 1.9 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EER25286.1 - 0.06 13.1 6.6 0.045 13.5 1.5 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DZR PF12773.2 EER25286.1 - 0.55 10.0 10.1 3.4 7.5 0.2 2.9 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EER25286.1 - 0.69 9.4 3.5 1.8 8.1 0.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-Apc11 PF12861.2 EER25286.1 - 2.5 7.9 7.0 0.21 11.4 0.9 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EER25286.1 - 7.8 6.1 10.0 1.1 8.8 1.9 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain WD40 PF00400.27 EER25287.1 - 1.3e-31 107.2 15.2 1.5e-08 34.1 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Proteasome PF00227.21 EER25288.1 - 1.5e-38 131.9 0.0 1.8e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.24 EER25289.1 - 3e-22 79.0 0.0 1.6e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EER25289.1 - 4.6e-12 45.8 0.1 8e-12 45.0 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EER25289.1 - 0.0048 16.3 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ring_hydroxyl_B PF00866.13 EER25290.1 - 0.052 13.2 1.0 0.12 12.1 0.7 1.5 1 0 0 1 1 1 0 Ring hydroxylating beta subunit WD40 PF00400.27 EER25291.1 - 1.9e-73 239.9 33.3 2.1e-09 36.8 0.1 12.2 11 2 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 EER25291.1 - 1.5e-45 154.2 0.0 2.3e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EER25291.1 - 5.3e-10 38.0 7.3 0.00059 18.1 0.6 4.5 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EER25291.1 - 0.00016 20.5 5.3 0.1 11.3 0.0 5.3 4 2 2 6 6 6 2 Nup133 N terminal like G-patch_2 PF12656.2 EER25292.1 - 2.2e-26 91.4 0.0 2.2e-26 91.4 0.0 3.3 3 1 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 EER25292.1 - 0.00099 18.8 0.4 0.00099 18.8 0.3 1.9 2 0 0 2 2 2 1 G-patch domain Phage_XkdX PF09693.5 EER25292.1 - 0.087 12.3 0.5 0.15 11.5 0.4 1.4 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) HSA PF07529.8 EER25293.1 - 5.1e-22 77.4 1.0 5.1e-22 77.4 0.7 3.3 3 1 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 EER25293.1 - 1.1e-16 60.6 1.1 5.8e-16 58.3 0.0 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER25293.1 - 0.00042 20.3 0.1 0.0011 19.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 EER25294.1 - 1.4e-10 40.5 0.1 0.081 12.8 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_M48 PF01435.13 EER25295.1 - 1.5e-51 175.1 0.0 2.5e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EER25295.1 - 0.0011 18.0 0.9 0.0016 17.5 0.1 1.5 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF4538 PF15061.1 EER25295.1 - 0.0093 15.2 1.0 0.026 13.8 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) DUF2201_N PF13203.1 EER25295.1 - 0.18 10.9 0.1 0.35 10.0 0.1 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_polI_A14 PF08203.6 EER25296.1 - 0.017 15.3 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 GTP_EFTU PF00009.22 EER25297.1 - 3.2e-39 134.3 0.0 5.1e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EER25297.1 - 2.4e-36 123.6 0.1 4.5e-36 122.7 0.1 1.5 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EER25297.1 - 7.6e-11 41.9 0.1 1.7e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EER25297.1 - 0.0039 17.1 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EER25297.1 - 0.067 13.0 0.0 0.44 10.3 0.0 2.3 3 0 0 3 3 3 0 Dynamin family Peptidase_M16_C PF05193.16 EER25298.1 - 3.5e-22 78.9 0.0 5.6e-15 55.4 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EER25298.1 - 0.0019 17.9 0.0 0.0064 16.2 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 EER25298.1 - 0.39 9.5 1.2 3.7 6.3 0.3 2.4 2 0 0 2 2 2 0 Peptidase M16C associated Zw10 PF06248.8 EER25299.1 - 1.3e-13 49.9 2.3 2.9e-06 25.7 0.6 3.3 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EER25299.1 - 5.7e-08 32.2 0.1 2.2e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 EER25299.1 - 0.0016 18.8 3.4 0.064 13.6 0.0 3.8 2 1 1 3 3 3 1 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.17 EER25299.1 - 0.01 15.8 3.9 3.2 7.7 0.7 3.2 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3701 PF12482.3 EER25299.1 - 0.036 13.8 0.9 0.3 10.8 0.1 2.4 2 0 0 2 2 2 0 Phage integrase protein Snapin_Pallidin PF14712.1 EER25299.1 - 0.15 12.4 1.4 9.8 6.5 0.6 3.2 2 0 0 2 2 2 0 Snapin/Pallidin WD40 PF00400.27 EER25300.1 - 1.7e-31 106.9 24.7 3e-08 33.2 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 EER25300.1 - 4.3e-20 71.5 0.1 7.3e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain DUF2855 PF11017.3 EER25300.1 - 0.036 13.2 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Ribosomal_S13 PF00416.17 EER25301.1 - 1.1e-23 83.7 0.0 1.8e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 EER25302.1 - 1.4e-47 161.7 0.3 1.7e-47 161.5 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CFEM PF05730.6 EER25303.1 - 1.4e-15 56.8 6.1 1.4e-15 56.8 4.2 1.5 2 0 0 2 2 2 1 CFEM domain Phage_holin_2 PF04550.7 EER25303.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage holin family 2 Fungal_trans_2 PF11951.3 EER25304.1 - 4.9e-10 38.5 0.1 0.00018 20.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain DEAD PF00270.24 EER25305.1 - 1.3e-46 158.2 0.0 5.2e-45 152.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER25305.1 - 2.6e-28 97.7 0.1 4.9e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25305.1 - 0.036 13.8 0.0 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EER25305.1 - 0.098 11.0 0.0 0.18 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EER25305.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AMP-binding PF00501.23 EER25306.1 - 0.13 10.5 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme TauD PF02668.11 EER25307.1 - 1.8e-20 73.6 0.1 2.2e-20 73.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EER25307.1 - 1.3e-05 24.2 0.0 1.8e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 CsiD Orn_Arg_deC_N PF02784.11 EER25308.1 - 1.2e-55 188.4 0.0 1.6e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EER25308.1 - 1.8e-22 79.2 0.0 3.8e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain CP_ATPgrasp_2 PF14403.1 EER25309.1 - 1.5e-06 27.1 0.0 0.0036 16.0 0.0 2.2 2 0 0 2 2 2 2 Circularly permuted ATP-grasp type 2 ATPgrasp_ST PF14397.1 EER25309.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp RWP-RK PF02042.10 EER25311.1 - 0.12 12.1 0.3 0.31 10.9 0.1 1.7 2 0 0 2 2 2 0 RWP-RK domain INSIG PF07281.7 EER25312.1 - 4.6e-58 195.7 0.6 5.7e-58 195.4 0.5 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) DEC-1_N PF04625.8 EER25312.1 - 0.057 12.0 1.0 0.086 11.4 0.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AICARFT_IMPCHas PF01808.13 EER25313.1 - 1.2e-110 369.5 0.0 1.9e-110 368.8 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EER25313.1 - 1.9e-26 91.8 0.0 3.6e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Clathrin PF00637.15 EER25314.1 - 2.3e-202 662.6 35.5 2.3e-36 124.5 0.8 7.5 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 EER25314.1 - 5.9e-29 99.7 0.2 2.4e-28 97.8 0.2 2.2 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 EER25314.1 - 6.4e-27 91.9 3.2 0.0034 17.5 0.1 7.7 7 0 0 7 7 7 7 Clathrin propeller repeat TPR_7 PF13176.1 EER25314.1 - 3.6e-05 23.2 1.7 30 4.7 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EER25314.1 - 0.0018 18.7 9.4 3.3 8.6 0.2 8.1 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER25314.1 - 0.011 15.9 0.1 44 4.5 0.0 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin-link PF09268.5 EER25314.1 - 0.014 14.3 0.6 0.035 13.1 0.4 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker CPSase_L_D2 PF02786.12 EER25315.1 - 1.4e-79 266.3 0.0 2.1e-79 265.7 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EER25315.1 - 3.2e-65 219.2 0.0 5.3e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EER25315.1 - 6.8e-36 122.7 0.0 1.4e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EER25315.1 - 9.2e-31 106.0 0.0 2.1e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EER25315.1 - 1.1e-25 90.6 0.0 2.7e-25 89.4 0.0 1.7 1 1 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 EER25315.1 - 2.2e-18 65.6 2.1 5.5e-18 64.3 1.3 1.9 2 0 0 2 2 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EER25315.1 - 7.4e-18 64.9 0.1 1.6e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EER25315.1 - 6.2e-14 51.4 0.0 2.7e-13 49.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EER25315.1 - 4.5e-10 39.0 1.6 7e-07 28.8 0.1 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EER25315.1 - 7.8e-09 35.2 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 EER25315.1 - 2.5e-06 27.1 0.0 6.6e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EER25315.1 - 7.9e-06 25.3 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EER25315.1 - 0.00025 20.9 0.0 0.00065 19.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_2 PF12700.2 EER25315.1 - 0.00036 19.8 0.0 0.18 10.8 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 EER25315.1 - 0.0038 16.5 0.1 0.023 13.9 0.0 2.2 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 EER25315.1 - 0.006 16.8 0.1 0.23 11.8 0.0 3.0 2 1 1 3 3 3 1 HlyD family secretion protein PYNP_C PF07831.8 EER25315.1 - 0.026 13.9 0.2 9.3 5.7 0.0 2.7 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain GARS_A PF01071.14 EER25315.1 - 0.044 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF1241 PF06840.6 EER25316.1 - 1.8e-05 24.0 39.5 0.52 9.5 0.4 11.3 1 1 11 12 12 12 4 Protein of unknown function (DUF1241) AAA_22 PF13401.1 EER25316.1 - 0.0021 18.2 5.0 0.0059 16.7 0.0 3.9 3 2 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EER25316.1 - 0.0058 16.6 0.0 0.032 14.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EER25316.1 - 0.14 11.8 0.0 0.8 9.5 0.0 2.3 1 0 0 1 1 1 0 Part of AAA domain Fibrinogen_BP PF08017.6 EER25316.1 - 0.23 9.6 6.1 0.097 10.8 2.6 1.6 2 0 0 2 2 2 0 Fibrinogen binding protein AAA_10 PF12846.2 EER25316.1 - 0.39 10.0 6.0 1.4 8.3 0.0 4.0 2 2 0 2 2 2 0 AAA-like domain HTH_Tnp_Tc5 PF03221.11 EER25316.1 - 0.82 9.5 38.7 33 4.3 0.1 13.1 1 1 13 15 15 15 0 Tc5 transposase DNA-binding domain Tetraspannin PF00335.15 EER25317.1 - 0.025 13.8 2.1 0.04 13.1 1.5 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF3671 PF12420.3 EER25317.1 - 0.13 12.2 0.8 0.2 11.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function SdpI PF13630.1 EER25317.1 - 1.6 8.4 5.3 5.1 6.8 3.7 1.8 1 1 0 1 1 1 0 SdpI/YhfL protein family AAA_16 PF13191.1 EER25318.1 - 0.00047 20.1 0.1 0.00095 19.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EER25318.1 - 0.0027 16.6 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain GMP_synt_C PF00958.17 EER25320.1 - 4.3e-35 119.3 0.0 8.7e-35 118.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EER25320.1 - 3.1e-31 108.3 0.0 5.4e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 EER25320.1 - 6.3e-09 35.0 0.0 1.9e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EER25320.1 - 7e-08 32.1 0.0 1.6e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 EER25320.1 - 0.00023 19.8 0.0 0.0011 17.5 0.0 1.9 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 EER25320.1 - 0.008 15.4 0.0 0.18 11.0 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.9 EER25320.1 - 0.013 14.9 0.0 0.033 13.6 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Arginosuc_synth PF00764.14 EER25320.1 - 0.014 14.4 0.1 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase PAPS_reduct PF01507.14 EER25320.1 - 0.043 13.6 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Asn_synthase PF00733.16 EER25320.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 EER25320.1 - 0.13 11.6 0.1 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 PP-loop family Ribosomal_L5_C PF00673.16 EER25321.1 - 4.2e-23 80.8 0.0 6e-23 80.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EER25321.1 - 2.2e-21 75.3 0.1 7.2e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 LSM PF01423.17 EER25322.1 - 9.7e-19 66.6 0.1 1.2e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain MPC PF03650.8 EER25323.1 - 3.8e-34 117.1 0.2 4.4e-34 116.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Med6 PF04934.9 EER25323.1 - 0.066 12.7 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 MED6 mediator sub complex component Aa_trans PF01490.13 EER25324.1 - 3.8e-83 279.2 30.6 4.7e-83 278.9 21.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease PF00324.16 EER25325.1 - 1.5e-59 201.6 33.2 1.8e-59 201.3 23.0 1.1 1 0 0 1 1 1 1 Amino acid permease HTH_23 PF13384.1 EER25326.1 - 3.6e-07 29.6 0.0 6.2e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EER25326.1 - 7.3e-06 26.1 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EER25326.1 - 0.00027 20.8 0.0 0.00057 19.8 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EER25326.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_7 PF02796.10 EER25326.1 - 0.024 14.5 0.1 0.068 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase HTH_17 PF12728.2 EER25326.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain CDC45 PF02724.9 EER25327.1 - 0.00012 20.3 3.9 0.00014 20.0 2.7 1.0 1 0 0 1 1 1 1 CDC45-like protein Nucleoplasmin PF03066.10 EER25327.1 - 0.041 13.3 3.9 0.053 13.0 2.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin zf-C2H2 PF00096.21 EER25327.1 - 0.064 13.6 0.9 0.064 13.6 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nop14 PF04147.7 EER25327.1 - 0.081 10.8 4.6 0.082 10.8 3.2 1.1 1 0 0 1 1 1 0 Nop14-like family Transpos_assoc PF13963.1 EER25327.1 - 0.22 11.5 4.9 0.28 11.2 0.7 2.4 3 0 0 3 3 2 0 Transposase-associated domain Daxx PF03344.10 EER25327.1 - 0.25 9.7 3.7 0.28 9.6 2.6 1.1 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EER25327.1 - 0.5 9.5 7.4 0.6 9.3 5.2 1.1 1 0 0 1 1 1 0 SDA1 RXT2_N PF08595.6 EER25327.1 - 0.69 9.7 4.4 1 9.1 3.0 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PPP4R2 PF09184.6 EER25327.1 - 0.78 9.2 6.1 1 8.8 4.3 1.1 1 0 0 1 1 1 0 PPP4R2 DUF2457 PF10446.4 EER25327.1 - 1.1 7.9 15.0 1.4 7.5 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 EER25327.1 - 1.5 8.5 6.0 2 8.0 4.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.8 EER25327.1 - 1.6 8.3 6.5 2.3 7.7 4.5 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region zf-H2C2_2 PF13465.1 EER25327.1 - 2 8.8 4.6 9.7 6.6 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain NOA36 PF06524.7 EER25327.1 - 2.2 7.4 14.2 0.057 12.6 5.0 1.7 2 0 0 2 2 2 0 NOA36 protein TFIIA PF03153.8 EER25327.1 - 2.9 7.7 9.5 3.5 7.4 6.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_4 PF13894.1 EER25327.1 - 5.1 7.6 7.6 0.75 10.2 0.4 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_M35 PF02102.10 EER25329.1 - 6e-99 331.0 0.8 7.1e-99 330.8 0.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EER25329.1 - 1.2e-09 38.8 0.1 2.2e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EER25329.1 - 0.0039 16.6 3.0 0.53 9.6 0.4 2.1 2 0 0 2 2 2 2 Putative peptidase family NB-ARC PF00931.17 EER25330.1 - 2e-05 23.6 0.0 2.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EER25330.1 - 0.0063 16.5 0.5 0.044 13.7 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EER25330.1 - 0.012 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EER25330.1 - 0.024 14.8 0.0 0.043 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EER25330.1 - 0.086 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Peptidase_M1 PF01433.15 EER25332.1 - 7e-74 249.2 0.0 9.5e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EER25332.1 - 2.4e-41 140.6 0.0 5.4e-41 139.5 0.0 1.6 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EER25332.1 - 2.5e-16 59.9 0.0 4.1e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EER25332.1 - 0.31 11.0 2.7 1.9 8.4 1.9 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Ribosomal_L38e PF01781.13 EER25333.1 - 5.5e-32 109.3 2.8 6.3e-32 109.1 2.0 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family NTF2 PF02136.15 EER25334.1 - 1.3e-07 31.9 0.9 4.8e-07 30.1 0.6 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EER25334.1 - 0.00096 18.9 0.0 0.0017 18.1 0.0 1.5 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.6 EER25335.1 - 2.6e-115 385.2 0.1 3.8e-115 384.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EER25335.1 - 5e-21 74.3 2.7 1.2e-10 40.0 0.0 3.8 3 2 2 5 5 5 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EER25335.1 - 1.1e-10 41.1 0.0 1.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain PALP PF00291.20 EER25336.1 - 4.8e-48 163.9 0.3 8.5e-48 163.1 0.2 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.17 EER25337.1 - 4.4e-35 117.5 17.5 5.5e-08 31.8 0.3 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat GHMP_kinases_N PF00288.21 EER25338.1 - 6e-19 67.8 0.1 1.2e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EER25338.1 - 2.2e-07 30.9 0.0 6.1e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EER25338.1 - 0.0089 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature zf-CCHC PF00098.18 EER25339.1 - 9.5e-06 25.3 3.4 1.4e-05 24.7 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EER25339.1 - 0.0065 15.9 0.3 0.016 14.6 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle Herpes_UL14 PF03580.9 EER25339.1 - 0.023 14.4 1.5 0.031 14.0 0.2 1.8 2 0 0 2 2 2 0 Herpesvirus UL14-like protein APH PF01636.18 EER25340.1 - 2.1e-09 37.4 0.0 9.5e-09 35.3 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family CHAT PF12770.2 EER25341.1 - 2.9e-34 118.5 0.0 4.4e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EER25341.1 - 4.1e-21 74.6 12.7 2.5e-05 24.1 0.0 7.5 5 2 2 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EER25341.1 - 1.8e-17 62.7 11.3 3.2e-07 29.9 0.1 6.1 3 2 3 7 7 7 4 TPR repeat TPR_17 PF13431.1 EER25341.1 - 8.3e-09 34.9 0.7 1.6 9.0 0.0 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EER25341.1 - 5.2e-05 22.8 15.3 7.2 6.8 0.0 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_10 PF13374.1 EER25341.1 - 0.13 12.2 29.7 1 9.3 0.2 9.2 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_8 PF13181.1 EER25341.1 - 0.2 11.4 3.1 26 4.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EER25341.1 - 0.53 11.0 6.8 31 5.3 0.0 5.9 4 2 2 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EER25341.1 - 0.64 9.7 8.4 6.6 6.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Histone PF00125.19 EER25343.1 - 8.5e-16 57.8 0.1 1.2e-15 57.3 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Nucleoplasmin PF03066.10 EER25343.1 - 0.0097 15.4 0.2 0.016 14.6 0.2 1.4 1 0 0 1 1 1 1 Nucleoplasmin CENP-S PF15630.1 EER25343.1 - 0.077 13.1 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S HNH_2 PF13391.1 EER25344.1 - 9.7e-16 57.3 0.8 2.6e-14 52.7 0.1 3.0 3 0 0 3 3 3 1 HNH endonuclease TraY PF05509.6 EER25344.1 - 0.099 12.4 0.3 0.22 11.3 0.2 1.5 1 0 0 1 1 1 0 TraY domain DDE_1 PF03184.14 EER25345.1 - 1e-56 191.5 1.8 1.2e-56 191.2 0.7 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EER25345.1 - 1.3e-16 60.1 2.8 3.6e-15 55.5 1.1 2.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain PhyH PF05721.8 EER25346.1 - 7.3e-28 98.0 0.0 1.1e-27 97.4 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 EER25347.1 - 3.6e-28 98.2 55.2 2.9e-27 95.3 37.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER25347.1 - 1.2e-16 60.1 24.7 1.6e-16 59.6 17.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER25347.1 - 1.9e-14 53.0 9.7 1.9e-14 53.0 6.7 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter adh_short PF00106.20 EER25348.1 - 5.2e-07 29.7 0.1 8.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase SLIDE PF09111.5 EER25348.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 SLIDE DUF3435 PF11917.3 EER25349.1 - 2.1e-94 316.5 8.1 2.6e-79 266.9 2.3 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) Pkinase PF00069.20 EER25350.1 - 1.2e-31 109.8 0.0 3.3e-31 108.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25350.1 - 8.1e-07 28.3 0.9 0.055 12.5 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase Vg_Tdu PF07545.9 EER25350.1 - 0.86 9.1 0.0 0.86 9.1 0.0 2.5 3 0 0 3 3 3 0 Vestigial/Tondu family PmrD PF11183.3 EER25351.1 - 0.13 12.1 0.0 0.81 9.5 0.0 2.1 2 1 1 3 3 3 0 Polymyxin resistance protein PmrD DUF4050 PF13259.1 EER25353.1 - 3.1e-38 130.4 0.2 5.9e-38 129.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) AAA PF00004.24 EER25354.1 - 7.9e-39 132.8 0.0 1.3e-37 128.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER25354.1 - 3.7e-05 23.7 0.1 0.005 16.8 0.0 3.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EER25354.1 - 8.3e-05 22.7 0.0 0.0027 17.8 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EER25354.1 - 0.00012 21.2 0.0 0.00025 20.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EER25354.1 - 0.00029 19.6 0.0 0.00061 18.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EER25354.1 - 0.0004 20.2 1.0 0.0055 16.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EER25354.1 - 0.00082 20.1 0.4 0.0038 18.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER25354.1 - 0.0009 18.9 0.0 0.0027 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EER25354.1 - 0.001 18.8 0.4 0.0038 16.9 0.2 2.0 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EER25354.1 - 0.0012 18.2 0.1 0.0094 15.3 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 EER25354.1 - 0.0037 17.2 0.1 0.014 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EER25354.1 - 0.014 14.5 0.0 0.037 13.2 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EER25354.1 - 0.016 15.1 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EER25354.1 - 0.022 14.9 0.0 0.074 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase SHQ1 PF04925.10 EER25354.1 - 0.033 13.6 0.0 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 SHQ1 protein AAA_24 PF13479.1 EER25354.1 - 0.041 13.4 0.2 0.15 11.6 0.2 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EER25354.1 - 0.043 14.1 0.4 0.17 12.1 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EER25354.1 - 0.077 12.5 3.5 0.72 9.3 0.0 3.3 3 1 0 3 3 3 0 AAA domain LIM_bind PF01803.11 EER25355.1 - 1.6e-72 243.4 0.0 1.6e-72 243.4 0.0 4.8 2 1 0 3 3 3 1 LIM-domain binding protein cobW PF02492.14 EER25356.1 - 1.1e-34 119.4 0.0 1.4e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EER25356.1 - 2.4e-07 29.7 0.1 0.00019 20.2 0.0 2.0 2 0 0 2 2 2 2 ArgK protein AAA_25 PF13481.1 EER25356.1 - 0.0092 15.4 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EER25356.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 EER25356.1 - 0.045 14.5 0.0 0.082 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DASH_Dad2 PF08654.5 EER25356.1 - 0.065 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 NACHT PF05729.7 EER25356.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EER25356.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase BING4CT PF08149.6 EER25357.1 - 8.7e-40 134.1 0.0 1.6e-36 123.6 0.0 2.9 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 EER25357.1 - 2.5e-05 23.9 0.0 0.0079 16.0 0.0 3.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EER25357.1 - 0.0037 16.1 0.0 0.58 8.8 0.0 2.5 3 0 0 3 3 3 2 Coatomer WD associated region DUF663 PF04950.7 EER25358.1 - 5.3e-95 317.8 0.0 9e-95 317.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EER25358.1 - 3.5e-23 80.9 0.0 8.2e-23 79.7 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain HlyIII PF03006.15 EER25359.1 - 9e-47 159.3 20.0 1.1e-46 159.0 13.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related ESSS PF10183.4 EER25359.1 - 0.17 12.2 3.2 4.4 7.7 0.2 2.6 2 1 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF726 PF05277.7 EER25360.1 - 7e-113 377.0 0.2 8.9e-113 376.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EER25360.1 - 6.1e-06 26.2 0.5 4.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EER25360.1 - 7.1e-05 23.1 0.1 0.00022 21.5 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 EER25360.1 - 0.0062 16.2 0.3 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EER25360.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_1 PF00561.15 EER25360.1 - 0.047 13.2 0.0 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.17 EER25360.1 - 0.14 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF2580 PF10824.3 EER25360.1 - 1 9.7 6.2 3 8.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) Methyltransf_23 PF13489.1 EER25361.1 - 5.7e-23 81.4 0.1 9.6e-23 80.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER25361.1 - 3.2e-11 43.7 0.1 4e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER25361.1 - 5.5e-11 42.8 0.0 4.4e-10 39.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER25361.1 - 3.8e-09 36.9 0.0 7.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER25361.1 - 8.2e-09 35.2 0.0 9.4e-08 31.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER25361.1 - 7.2e-07 29.5 0.0 3.6e-06 27.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER25361.1 - 0.00011 21.4 0.0 0.011 14.9 0.0 2.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EER25361.1 - 0.00041 19.4 0.0 0.0013 17.8 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EER25361.1 - 0.00052 19.4 0.0 0.002 17.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EER25361.1 - 0.0028 17.1 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EER25361.1 - 0.0057 15.8 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EER25361.1 - 0.013 15.4 0.1 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 EER25361.1 - 0.064 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) SNAP PF14938.1 EER25362.1 - 7.8e-115 382.8 18.8 8.9e-115 382.6 13.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EER25362.1 - 7.2e-07 29.0 12.1 0.00043 20.1 2.2 3.0 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER25362.1 - 2.9e-05 24.5 12.5 0.17 12.5 0.4 3.7 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EER25362.1 - 0.00035 20.8 12.1 8.7 7.0 0.1 6.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EER25362.1 - 0.0012 18.5 13.8 0.68 10.0 0.1 6.7 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EER25362.1 - 0.0052 16.4 15.3 0.37 10.4 1.8 3.9 1 1 3 4 4 4 4 TPR repeat TPR_14 PF13428.1 EER25362.1 - 0.0055 17.2 9.1 2.9 8.7 0.4 5.0 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER25362.1 - 0.0078 15.9 11.5 0.54 10.1 0.4 5.5 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER25362.1 - 0.024 14.4 13.5 1.3 9.0 0.1 6.2 4 1 2 6 6 6 0 Tetratricopeptide repeat DFF40 PF09230.5 EER25362.1 - 0.064 12.6 0.2 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa MIT PF04212.13 EER25362.1 - 0.12 12.2 8.1 4 7.3 0.6 4.5 2 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EER25362.1 - 0.33 10.8 12.2 8.5 6.2 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EER25362.1 - 0.73 9.5 16.3 1.3 8.7 0.5 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat Ank PF00023.25 EER25363.1 - 2.3e-09 36.6 0.3 1.9e-05 24.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EER25363.1 - 9.9e-09 35.4 0.1 3.2e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER25363.1 - 3.1e-06 27.5 0.1 3.1e-05 24.3 0.0 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER25363.1 - 3.9e-05 23.4 0.4 0.0083 16.2 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EER25363.1 - 4.7e-05 23.4 0.0 0.00036 20.6 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Torsin PF06309.6 EER25363.1 - 0.11 12.3 0.1 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Torsin Pyr_redox_2 PF07992.9 EER25365.1 - 1.2e-05 25.2 0.0 8e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER25365.1 - 2.2e-05 24.6 0.0 0.0086 16.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER25365.1 - 0.029 14.3 0.0 0.1 12.6 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EER25365.1 - 0.052 12.0 0.0 0.079 11.4 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EER25365.1 - 0.15 10.8 0.6 1.6 7.4 0.1 2.4 2 1 0 2 2 2 0 FAD binding domain Lectin_C PF00059.16 EER25366.1 - 0.031 14.9 1.0 0.11 13.2 0.1 2.3 3 0 0 3 3 3 0 Lectin C-type domain Sec62 PF03839.11 EER25367.1 - 2.1e-52 177.7 0.6 2.1e-52 177.7 0.4 2.1 2 0 0 2 2 2 1 Translocation protein Sec62 Zip PF02535.17 EER25367.1 - 0.0032 16.5 15.0 1.1 8.1 11.5 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter HTH_18 PF12833.2 EER25367.1 - 0.034 14.2 0.5 0.098 12.7 0.3 1.8 1 1 1 2 2 2 0 Helix-turn-helix domain Mcm10 PF09332.6 EER25368.1 - 1.7 7.9 7.3 4.4 6.5 5.1 1.7 1 0 0 1 1 1 0 Mcm10 replication factor Abhydrolase_6 PF12697.2 EER25369.1 - 3.6e-24 85.8 0.5 6.7e-24 85.0 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER25369.1 - 2.8e-09 36.8 0.0 4.7e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER25369.1 - 3.3e-07 30.1 0.0 8.9e-07 28.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EER25369.1 - 0.052 13.1 0.4 0.78 9.3 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase Hydrolase_4 PF12146.3 EER25369.1 - 0.11 12.3 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Ndr PF03096.9 EER25369.1 - 0.16 10.4 0.0 13 4.1 0.0 2.5 3 0 0 3 3 3 0 Ndr family priB_priC PF07445.7 EER25370.1 - 0.0013 18.2 2.0 0.0028 17.1 1.4 1.5 1 0 0 1 1 1 1 Primosomal replication protein priB and priC DivIC PF04977.10 EER25370.1 - 0.11 12.0 0.0 0.11 12.0 0.0 2.5 2 1 0 2 2 2 0 Septum formation initiator DUF2968 PF11180.3 EER25370.1 - 0.34 10.2 12.0 0.78 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) HemX PF04375.9 EER25370.1 - 0.43 9.1 7.7 1.2 7.6 4.8 1.9 2 0 0 2 2 2 0 HemX DUF2046 PF09755.4 EER25370.1 - 1.4 7.7 9.9 0.32 9.8 4.3 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DASH_Spc34 PF08657.5 EER25370.1 - 2.4 7.7 9.1 40 3.7 5.4 2.6 2 1 0 2 2 2 0 DASH complex subunit Spc34 FlaC_arch PF05377.6 EER25370.1 - 4.6 7.1 5.9 10 6.0 1.2 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Spc24 PF08286.6 EER25370.1 - 6.6 6.4 7.1 48 3.6 0.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Carn_acyltransf PF00755.15 EER25371.1 - 1.4e-180 601.3 0.0 1.6e-180 601.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Glyco_transf_90 PF05686.7 EER25372.1 - 5.6e-31 107.6 0.1 7.7e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EER25372.1 - 0.0049 17.1 0.1 0.011 15.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Rxt3 PF08642.5 EER25373.1 - 3.1e-26 91.8 0.0 6.8e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EER25373.1 - 0.00067 19.5 0.0 0.0024 17.8 0.0 1.9 2 0 0 2 2 2 1 LCCL domain CLN3 PF02487.12 EER25374.1 - 1.4e-100 336.9 18.9 2.9e-53 181.1 0.3 3.0 1 1 1 2 2 2 2 CLN3 protein Abhydrolase_3 PF07859.8 EER25375.1 - 3e-36 125.0 0.0 8.5e-26 90.8 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EER25375.1 - 0.0022 16.6 0.0 0.0036 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Aminotran_3 PF00202.16 EER25376.1 - 1.1e-95 320.3 0.0 1.4e-95 320.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EER25376.1 - 0.00013 21.0 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II UBN2 PF14223.1 EER25377.1 - 0.0001 22.1 1.3 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Ribosomal_60s PF00428.14 EER25377.1 - 0.052 13.9 0.6 0.12 12.8 0.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4106 PF13388.1 EER25377.1 - 0.89 8.4 9.2 1.3 7.9 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) IncA PF04156.9 EER25377.1 - 2.1 7.9 8.0 3.8 7.0 5.5 1.4 1 0 0 1 1 1 0 IncA protein HMGL-like PF00682.14 EER25378.1 - 1.2e-39 136.3 0.6 1.9e-38 132.4 0.4 2.0 1 1 0 1 1 1 1 HMGL-like Diphthamide_syn PF01866.12 EER25379.1 - 3.7e-112 374.5 0.0 4.3e-112 374.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Bromodomain PF00439.20 EER25380.1 - 1.9e-16 59.7 0.0 4.3e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Bromodomain TelA PF05816.6 EER25381.1 - 0.0081 14.8 1.0 0.0098 14.6 0.7 1.1 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) ADIP PF11559.3 EER25381.1 - 0.028 14.3 3.8 0.04 13.8 2.6 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FliD_C PF07195.7 EER25381.1 - 0.034 13.4 0.6 0.059 12.6 0.4 1.4 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Atg14 PF10186.4 EER25381.1 - 0.073 12.0 2.4 0.088 11.7 1.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Allexi_40kDa PF05549.6 EER25381.1 - 0.085 12.1 4.8 0.12 11.6 2.2 1.7 1 1 1 2 2 2 0 Allexivirus 40kDa protein OSCP PF00213.13 EER25382.1 - 9.7e-42 142.7 4.3 1.3e-41 142.3 3.0 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF1539 PF07560.6 EER25382.1 - 0.0057 16.5 0.6 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1539) DUF148 PF02520.12 EER25382.1 - 0.14 11.9 1.8 0.22 11.2 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF148 Mob1_phocein PF03637.12 EER25383.1 - 1.2e-71 239.9 0.0 1.5e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family Rgp1 PF08737.5 EER25384.1 - 1.5e-109 366.8 0.0 2e-109 366.4 0.0 1.2 1 0 0 1 1 1 1 Rgp1 Spo0M PF07070.6 EER25384.1 - 0.0059 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 SpoOM protein Arrestin_N PF00339.24 EER25384.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Neugrin PF06413.6 EER25385.1 - 6e-13 49.1 2.3 7.7e-13 48.7 0.3 1.8 1 1 1 2 2 2 1 Neugrin MRP-L20 PF12824.2 EER25385.1 - 3.1e-06 27.2 13.3 1.2e-05 25.3 9.2 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 FeoC PF09012.5 EER25385.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_29 PF13551.1 EER25385.1 - 0.033 14.3 0.1 0.033 14.3 0.1 2.9 2 1 1 3 3 3 0 Winged helix-turn helix Sigma70_r3 PF04539.11 EER25385.1 - 0.038 13.8 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Sigma-70 region 3 WD40 PF00400.27 EER25386.1 - 5.8e-23 79.8 16.6 9e-06 25.3 0.0 9.1 9 0 0 9 9 9 6 WD domain, G-beta repeat SPO22 PF08631.5 EER25387.1 - 6.6e-43 146.7 2.3 1.1e-24 86.9 0.5 3.1 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EER25387.1 - 8e-06 25.6 1.7 0.054 13.4 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EER25387.1 - 0.16 11.9 3.4 2.5 8.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.13 EER25388.1 - 6.8e-06 25.8 9.9 1.2e-05 25.0 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-Q PF13094.1 EER25389.1 - 6.5e-50 169.2 5.2 9.9e-50 168.6 3.6 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit CCDC144C PF14915.1 EER25389.1 - 0.02 13.8 6.4 0.038 12.9 4.5 1.4 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region IncA PF04156.9 EER25389.1 - 0.066 12.8 2.4 0.12 12.0 1.7 1.5 1 0 0 1 1 1 0 IncA protein DUF2203 PF09969.4 EER25389.1 - 0.07 13.3 1.3 0.51 10.5 0.0 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Ran-binding PF05508.6 EER25389.1 - 0.19 10.5 2.5 0.5 9.2 0.5 2.1 2 0 0 2 2 2 0 RanGTP-binding protein DUF904 PF06005.7 EER25389.1 - 0.24 11.7 13.9 0.076 13.3 7.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4337 PF14235.1 EER25389.1 - 0.4 10.5 5.5 0.77 9.5 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) COG2 PF06148.6 EER25389.1 - 0.78 9.6 6.2 2.8 7.8 2.5 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 EER25389.1 - 3.5 7.9 6.9 6.3 7.1 2.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EER25389.1 - 7.2 6.3 7.2 4.2 7.0 2.9 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 HLH PF00010.21 EER25390.1 - 1.5e-08 34.1 0.0 3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Oxidored-like PF09791.4 EER25391.1 - 0.052 12.9 0.8 0.1 12.0 0.5 1.4 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal HD PF01966.17 EER25392.1 - 0.002 18.1 0.2 0.0035 17.3 0.1 1.4 1 0 0 1 1 1 1 HD domain CtaG_Cox11 PF04442.9 EER25393.1 - 3.6e-60 202.1 0.1 5.4e-60 201.5 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Rep_fac_C PF08542.6 EER25394.1 - 3.7e-23 81.3 0.1 9.2e-23 80.0 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EER25394.1 - 4.3e-11 42.7 0.1 8.4e-11 41.7 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EER25394.1 - 2.2e-06 27.9 0.1 4.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER25394.1 - 2.2e-05 24.5 0.4 0.00018 21.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EER25394.1 - 0.00028 20.9 0.9 0.015 15.2 0.6 2.5 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EER25394.1 - 0.0024 17.9 0.3 0.11 12.5 0.2 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.1 EER25394.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain T4SS-DNA_transf PF02534.9 EER25394.1 - 0.049 12.2 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 EER25394.1 - 0.05 12.3 0.1 0.07 11.9 0.1 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EER25394.1 - 0.059 12.7 0.1 2.1 7.6 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain ABC_tran PF00005.22 EER25394.1 - 0.073 13.3 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EER25394.1 - 0.14 11.6 0.0 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Ribosomal_L16 PF00252.13 EER25395.1 - 2e-33 114.9 0.3 2.8e-33 114.4 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 EER25396.1 - 3.5e-58 195.7 0.1 7.8e-58 194.6 0.0 1.6 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EER25396.1 - 7.4e-12 45.2 0.0 2e-11 43.8 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EER25396.1 - 8e-10 39.0 0.2 3.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER25396.1 - 1.9e-06 28.0 0.0 5.9e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EER25396.1 - 2.8e-05 24.9 0.2 9.3e-05 23.2 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EER25396.1 - 0.00084 19.3 0.0 0.014 15.3 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EER25396.1 - 0.0018 18.0 0.1 0.0049 16.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 EER25396.1 - 0.002 16.8 0.0 0.0044 15.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 EER25396.1 - 0.0031 17.3 0.0 0.0082 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EER25396.1 - 0.0039 16.2 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EER25396.1 - 0.0086 16.3 0.0 0.032 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EER25396.1 - 0.0091 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER25396.1 - 0.047 13.4 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EER25396.1 - 0.05 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EER25396.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EER25396.1 - 0.11 12.1 0.0 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain NAD_binding_8 PF13450.1 EER25397.1 - 2.4e-15 56.2 0.0 7.8e-15 54.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EER25397.1 - 1.7e-06 27.4 0.0 0.0061 15.6 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.19 EER25397.1 - 0.00081 18.3 0.0 0.015 14.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EER25397.1 - 0.031 14.3 0.0 2.6 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER25397.1 - 0.037 14.4 0.0 4.9 7.6 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EER25397.1 - 0.085 11.8 0.0 0.26 10.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EER25397.1 - 0.21 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Septin PF00735.13 EER25398.1 - 1.5e-123 411.2 0.2 1.5e-123 411.2 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EER25398.1 - 2.1e-07 30.8 0.0 4.8e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER25398.1 - 2.2e-05 23.9 1.3 0.0018 17.7 0.0 3.1 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EER25398.1 - 4.6e-05 22.6 0.5 0.00042 19.5 0.3 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EER25398.1 - 7.8e-05 22.9 3.0 0.013 15.7 0.0 2.7 2 1 1 3 3 3 1 ABC transporter AAA_10 PF12846.2 EER25398.1 - 0.00022 20.7 1.6 0.00092 18.7 1.0 2.2 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EER25398.1 - 0.001 19.1 0.1 0.011 15.6 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain Miro PF08477.8 EER25398.1 - 0.0017 18.8 0.4 0.0086 16.5 0.0 2.4 3 0 0 3 3 2 1 Miro-like protein AIG1 PF04548.11 EER25398.1 - 0.0019 17.3 3.1 0.0023 17.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family AAA_22 PF13401.1 EER25398.1 - 0.0036 17.4 0.1 0.015 15.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain Ras PF00071.17 EER25398.1 - 0.0047 16.3 0.1 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.1 EER25398.1 - 0.0061 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EER25398.1 - 0.011 15.1 1.7 0.02 14.4 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EER25398.1 - 0.013 15.0 0.1 2.6 7.4 0.0 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.10 EER25398.1 - 0.017 14.3 5.8 0.027 13.6 4.0 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.18 EER25398.1 - 0.02 14.7 6.8 0.46 10.2 0.0 3.4 3 1 0 3 3 3 0 Dynamin family AAA_32 PF13654.1 EER25398.1 - 0.048 12.3 10.5 0.36 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EER25398.1 - 0.054 13.0 1.2 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EER25398.1 - 0.062 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EER25398.1 - 0.077 13.1 0.6 0.43 10.7 0.0 2.4 2 0 0 2 2 2 0 RNA helicase MAP7 PF05672.6 EER25398.1 - 0.098 12.0 15.5 0.14 11.4 10.7 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family MobB PF03205.9 EER25398.1 - 0.11 12.1 1.2 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Strep_SA_rep PF06696.6 EER25398.1 - 0.13 12.0 1.5 0.25 11.1 0.8 1.7 1 1 0 1 1 1 0 Streptococcal surface antigen repeat DUF87 PF01935.12 EER25398.1 - 0.74 9.5 4.6 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 Phage_GPO PF05929.6 EER25398.1 - 1.1 8.4 6.7 1.7 7.7 4.6 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 EER25398.1 - 3 7.4 9.6 4.6 6.8 6.7 1.3 1 0 0 1 1 1 0 IncA protein UPF0121 PF03661.8 EER25399.1 - 2.3e-14 53.1 1.8 3.6e-14 52.5 1.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) UPF0060 PF02694.10 EER25399.1 - 0.029 14.3 0.8 0.029 14.3 0.6 2.3 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Mito_carr PF00153.22 EER25400.1 - 2.6e-64 212.9 0.4 4.2e-21 74.4 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein ORC6 PF05460.8 EER25401.1 - 1.4 7.9 6.6 1.9 7.4 4.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CHCH PF06747.8 EER25402.1 - 4.1e-08 32.9 2.7 7.2e-08 32.1 1.8 1.4 1 0 0 1 1 1 1 CHCH domain UreF PF01730.11 EER25402.1 - 0.89 9.6 3.6 0.31 11.1 0.2 1.9 2 0 0 2 2 2 0 UreF TPK_catalytic PF04263.11 EER25404.1 - 4.9e-20 71.3 0.0 3.1e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EER25404.1 - 9.8e-19 66.8 0.0 1.6e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain MIF4G PF02854.14 EER25405.1 - 2e-59 200.4 0.0 3.9e-29 101.5 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EER25405.1 - 3.7e-59 199.3 21.3 3.7e-59 199.3 14.8 3.0 3 0 0 3 3 3 1 Up-frameshift suppressor 2 Pyr_redox_3 PF13738.1 EER25406.1 - 1.6e-26 93.6 0.0 2.6e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER25406.1 - 1.2e-22 79.8 0.1 8.1e-21 73.8 0.1 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EER25406.1 - 1.6e-10 40.8 0.0 5.5e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EER25406.1 - 3.9e-10 39.1 0.2 1.1e-07 31.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EER25406.1 - 1.1e-06 28.6 0.0 3e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EER25406.1 - 1.2e-06 27.6 0.0 2.2e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EER25406.1 - 5.8e-05 22.2 0.1 0.00014 21.0 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EER25406.1 - 8.5e-05 22.3 0.0 0.00046 19.9 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EER25406.1 - 0.00014 21.9 0.1 0.13 12.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EER25406.1 - 0.0024 16.7 0.3 0.0037 16.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EER25406.1 - 0.006 16.9 0.2 4.1 7.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase APP_N PF02177.11 EER25406.1 - 0.045 13.6 2.3 0.1 12.5 1.6 1.5 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding FAD_binding_3 PF01494.14 EER25406.1 - 0.058 12.4 0.3 0.34 9.8 0.3 1.9 2 0 0 2 2 2 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EER25406.1 - 0.17 11.0 0.1 0.54 9.3 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EER25406.1 - 0.23 9.8 0.8 0.41 9.0 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_18 PF00704.23 EER25407.1 - 2.9e-97 326.1 2.4 3.6e-97 325.8 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EER25407.1 - 2.2e-14 53.0 0.0 4.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 LysM domain Glyco_transf_8 PF01501.15 EER25409.1 - 8.1e-10 38.4 0.0 9.4e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 SUN PF03856.8 EER25410.1 - 3.4e-99 331.1 10.3 4.2e-99 330.8 7.2 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF1768 PF08719.6 EER25411.1 - 9.9e-50 168.3 0.0 1.2e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Ribosomal_L1 PF00687.16 EER25412.1 - 8.8e-55 185.4 4.2 2.1e-54 184.1 2.9 1.7 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family ETF PF01012.16 EER25413.1 - 1.1e-42 145.5 3.8 1.9e-42 144.7 2.6 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EER25413.1 - 6.2e-35 118.6 0.1 1.3e-34 117.6 0.1 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain AAA PF00004.24 EER25414.1 - 2.7e-11 43.7 0.0 5.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER25414.1 - 7.7e-06 26.0 0.0 2.5e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER25414.1 - 2.5e-05 24.0 0.0 5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EER25414.1 - 7.9e-05 21.8 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EER25414.1 - 0.00021 20.9 0.0 0.0006 19.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EER25414.1 - 0.00065 20.5 0.2 0.0033 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.10 EER25414.1 - 0.0011 17.7 0.0 0.0019 16.9 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EER25414.1 - 0.0014 18.4 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER25414.1 - 0.0019 18.0 0.0 0.0057 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER25414.1 - 0.0034 17.3 0.1 0.025 14.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EER25414.1 - 0.011 14.8 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF258 PF03193.11 EER25414.1 - 0.016 14.3 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EER25414.1 - 0.042 13.5 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 NTPase IstB_IS21 PF01695.12 EER25414.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 EER25414.1 - 0.073 11.9 0.1 0.28 10.0 0.1 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 EER25414.1 - 0.076 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EER25414.1 - 0.076 12.9 0.2 0.26 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 EER25414.1 - 0.14 11.7 0.5 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain SWIRM PF04433.12 EER25415.1 - 3.6e-34 116.7 0.1 8.6e-34 115.5 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EER25415.1 - 1.9e-06 27.8 0.2 3.6e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER25415.1 - 3.5e-05 23.8 0.3 0.0001 22.3 0.2 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EER25415.1 - 0.0047 16.4 4.8 0.074 12.5 3.3 2.2 1 1 0 1 1 1 1 Zinc finger, ZZ type DUF389 PF04087.9 EER25415.1 - 0.19 11.6 0.4 0.35 10.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF389) ResIII PF04851.10 EER25417.1 - 9.3e-24 84.2 0.0 2e-23 83.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EER25417.1 - 1.1e-13 50.7 0.0 2.6e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EER25417.1 - 3.5e-11 42.9 0.0 6.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EER25417.1 - 0.00053 19.0 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 EER25417.1 - 0.063 12.0 0.1 0.13 11.0 0.1 1.5 1 1 0 1 1 1 0 SNF2 family N-terminal domain PGAP1 PF07819.8 EER25418.1 - 2.7e-82 275.7 0.0 6.1e-82 274.5 0.0 1.6 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EER25418.1 - 7.9e-06 25.6 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER25418.1 - 0.00027 20.8 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER25418.1 - 0.0028 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EER25418.1 - 0.0066 15.7 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 EER25418.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EER25418.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EER25418.1 - 0.14 11.5 0.1 0.38 10.1 0.0 1.6 2 0 0 2 2 2 0 Putative esterase COesterase PF00135.23 EER25418.1 - 0.23 10.1 0.0 0.33 9.6 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family NAD_binding_10 PF13460.1 EER25419.1 - 4e-06 26.9 0.0 1.3e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EER25419.1 - 0.008 15.4 0.1 0.023 13.9 0.0 1.7 3 0 0 3 3 3 1 NmrA-like family MFS_1 PF07690.11 EER25420.1 - 1.1e-19 70.3 14.0 1.7e-10 40.1 3.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PQ-loop PF04193.9 EER25420.1 - 0.071 12.6 1.6 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 PQ loop repeat adh_short PF00106.20 EER25421.1 - 3.8e-21 75.7 1.6 1.2e-10 41.5 0.2 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EER25421.1 - 1.2e-08 35.0 0.7 1.3e-07 31.6 0.5 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER25421.1 - 1.6e-05 24.6 1.0 0.00068 19.3 0.7 2.2 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EER25421.1 - 0.0043 16.8 0.4 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EER25421.1 - 0.014 15.0 0.2 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EER25421.1 - 0.017 15.1 2.8 4.3 7.3 2.0 2.8 1 1 0 1 1 1 0 NADH(P)-binding ADH_zinc_N PF00107.21 EER25421.1 - 0.035 13.6 0.4 1.4 8.4 0.2 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Epimerase PF01370.16 EER25421.1 - 0.11 11.8 0.1 0.44 9.9 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family APG17 PF04108.7 EER25422.1 - 4.3e-118 394.6 0.4 5e-118 394.4 0.3 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 DUF2365 PF10157.4 EER25422.1 - 0.03 14.1 0.3 0.11 12.4 0.1 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) FliE PF02049.13 EER25422.1 - 0.05 13.6 0.4 0.6 10.1 0.1 2.6 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE LMP PF04778.7 EER25422.1 - 0.059 13.1 2.6 9.8 5.9 0.0 3.0 3 0 0 3 3 3 0 LMP repeated region Fib_alpha PF08702.5 EER25422.1 - 0.84 9.7 5.1 1.4 9.0 0.1 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.1 EER25422.1 - 2.9 8.2 7.2 29 5.0 0.0 3.7 5 0 0 5 5 5 0 Snapin/Pallidin WD40 PF00400.27 EER25423.1 - 5.7e-58 190.8 24.7 3.5e-10 39.3 0.0 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EER25423.1 - 5.9e-14 51.5 1.3 1.3e-13 50.4 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER25423.1 - 8.9e-11 41.1 1.7 1.7e-10 40.2 0.7 1.9 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.3 EER25423.1 - 2.3e-09 35.9 8.0 0.009 14.1 0.1 4.8 2 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EER25423.1 - 0.033 12.9 1.3 2.3 6.8 0.1 2.6 1 1 1 2 2 2 0 Nup133 N terminal like PRANC PF09372.5 EER25423.1 - 0.085 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 PRANC domain RIO1 PF01163.17 EER25426.1 - 3.4e-74 248.3 0.1 3.4e-74 248.3 0.1 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EER25426.1 - 0.00025 20.8 0.1 0.036 13.8 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EER25426.1 - 0.0016 17.5 0.1 1 8.4 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.14 EER25427.1 - 3.1e-66 222.7 21.5 9.3e-66 221.1 14.9 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EER25427.1 - 1.9e-33 114.9 0.2 4.3e-32 110.6 0.0 3.1 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EER25427.1 - 3.5e-16 60.0 11.8 5.3e-10 39.7 0.0 4.0 4 1 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EER25427.1 - 3.4e-12 47.1 31.6 3.4e-12 47.1 21.9 6.9 2 2 2 4 4 2 1 AAA domain AAA_15 PF13175.1 EER25427.1 - 1.9e-08 33.7 13.9 1.9e-08 33.7 9.6 3.0 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EER25427.1 - 0.00031 20.2 0.0 0.00073 19.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EER25427.1 - 0.00079 18.0 94.6 0.0018 16.8 19.4 6.4 3 2 2 6 6 6 4 AAA domain COG5 PF10392.4 EER25427.1 - 0.0046 16.9 5.1 0.0046 16.9 3.5 6.2 5 2 2 7 7 7 1 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 EER25427.1 - 0.005 16.0 25.0 0.56 9.3 2.3 5.1 2 2 3 5 5 5 3 Reovirus sigma C capsid protein ABC_tran PF00005.22 EER25427.1 - 0.38 11.0 0.0 0.38 11.0 0.0 5.9 3 2 0 3 3 1 0 ABC transporter IncA PF04156.9 EER25427.1 - 1.8 8.1 115.4 0.22 11.0 5.9 7.2 3 2 4 7 7 6 0 IncA protein DUF3605 PF12239.3 EER25428.1 - 1.6e-56 190.5 0.0 1.9e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.19 EER25429.1 - 3.9e-29 100.7 0.0 7.1e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EER25429.1 - 6.1e-27 94.3 0.0 1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EER25429.1 - 1.1e-06 28.6 0.0 0.00049 20.0 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EER25429.1 - 0.00077 19.4 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF1138 PF06592.8 EER25429.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) DUF4176 PF13780.1 EER25429.1 - 0.096 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) tRNA-synt_1d PF00750.14 EER25430.1 - 2.9e-81 273.0 7.9 6.7e-45 153.4 4.1 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 EER25430.1 - 4.2e-28 97.7 0.0 1e-27 96.4 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EER25430.1 - 3.5e-05 24.2 0.0 9.5e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.6 EER25430.1 - 0.049 12.2 0.3 1.3 7.5 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (M) Pkinase PF00069.20 EER25435.1 - 2.2e-25 89.3 0.0 3.4e-25 88.6 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25435.1 - 8e-09 34.9 0.0 1.3e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DEAD PF00270.24 EER25436.1 - 1.2e-40 138.7 1.7 1.6e-40 138.3 0.7 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER25436.1 - 1.9e-22 78.8 0.3 1.3e-11 44.2 0.0 2.9 3 1 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EER25436.1 - 2.2e-05 24.3 0.0 7.6e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AA_permease PF00324.16 EER25438.1 - 2e-115 385.8 40.4 3.1e-115 385.2 28.0 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER25438.1 - 1.4e-28 99.6 45.4 2.3e-28 98.9 30.7 1.7 1 1 0 1 1 1 1 Amino acid permease SVM_signal PF12113.3 EER25438.1 - 0.33 10.8 4.4 1 9.2 3.1 1.8 1 0 0 1 1 1 0 SVM protein signal sequence Acyltransferase PF01553.16 EER25439.1 - 1.2e-13 50.6 0.0 2.1e-13 49.8 0.0 1.4 1 1 0 1 1 1 1 Acyltransferase L31 PF09784.4 EER25440.1 - 8.6e-48 160.6 2.6 9.6e-48 160.5 1.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF2161 PF09929.4 EER25440.1 - 0.063 13.2 0.1 0.081 12.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Spb1_C PF07780.7 EER25440.1 - 0.11 11.9 3.0 0.13 11.7 2.1 1.1 1 0 0 1 1 1 0 Spb1 C-terminal domain DUF605 PF04652.11 EER25442.1 - 0.24 10.7 11.2 0.25 10.6 7.8 1.1 1 0 0 1 1 1 0 Vta1 like Annexin PF00191.15 EER25443.1 - 1.7e-63 210.4 7.5 3.4e-18 65.2 0.3 4.1 4 0 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 EER25443.1 - 0.011 15.9 0.3 5.8 7.2 0.0 3.3 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EBP PF05241.7 EER25444.1 - 4e-63 211.9 9.6 4.6e-63 211.7 6.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2910 PF11139.3 EER25444.1 - 7.3 5.6 11.1 0.088 11.9 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2910) zf-C3HC4 PF00097.20 EER25445.1 - 9.5e-08 31.5 4.3 9.5e-08 31.5 3.0 5.0 5 1 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) SH3_9 PF14604.1 EER25445.1 - 7e-06 25.5 0.2 7e-06 25.5 0.2 2.8 3 0 0 3 3 3 1 Variant SH3 domain zf-RING_6 PF14835.1 EER25445.1 - 1e-05 25.2 0.3 1e-05 25.2 0.2 2.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.1 EER25445.1 - 1.5e-05 24.9 5.7 1.5e-05 24.9 4.0 4.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EER25445.1 - 0.0013 18.3 1.0 0.0013 18.3 0.7 2.5 2 0 0 2 2 2 1 RING-type zinc-finger SH3_1 PF00018.23 EER25445.1 - 0.0068 15.7 0.2 0.0068 15.7 0.1 2.1 2 0 0 2 2 2 1 SH3 domain DUF905 PF06006.7 EER25446.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) CBM_21 PF03370.8 EER25447.1 - 2.2e-35 121.0 1.0 4.2e-35 120.1 0.7 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Apt1 PF10351.4 EER25447.1 - 6.7 5.4 6.9 13 4.5 4.8 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Histone PF00125.19 EER25448.1 - 1.2e-15 57.3 0.5 1.5e-15 57.0 0.4 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EER25448.1 - 4.2e-05 23.3 0.2 6e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EER25448.1 - 4.3e-05 23.5 0.1 6.4e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EER25448.1 - 5.9e-05 23.0 0.2 9.6e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EER25448.1 - 0.0037 16.5 0.0 0.0039 16.5 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EER25448.1 - 0.004 16.8 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EER25448.1 - 0.041 14.1 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 EER25448.1 - 0.1 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Mito_carr PF00153.22 EER25449.1 - 1.4e-23 82.3 0.2 1.7e-08 34.0 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein SIN1 PF05422.7 EER25450.1 - 1.1e-31 109.9 1.7 1.6e-20 73.1 0.8 2.5 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EER25450.1 - 0.0012 18.7 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Pkinase PF00069.20 EER25451.1 - 3.3e-69 232.9 0.0 4.2e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25451.1 - 5.1e-37 127.3 0.0 6.9e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER25451.1 - 1.5e-06 27.4 0.0 2.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rad21_Rec8 PF04824.11 EER25451.1 - 0.09 11.9 0.5 0.21 10.8 0.3 1.5 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein zf-Tim10_DDP PF02953.10 EER25452.1 - 6e-19 67.0 0.9 7.8e-19 66.7 0.7 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger NatB_MDM20 PF09797.4 EER25452.1 - 0.074 11.7 1.0 0.086 11.5 0.7 1.0 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit zf-CCHC_3 PF13917.1 EER25452.1 - 0.13 11.9 0.4 0.34 10.6 0.3 1.7 1 1 0 1 1 1 0 Zinc knuckle Lectin_leg-like PF03388.8 EER25453.1 - 6.2e-62 208.7 0.0 8.5e-62 208.2 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EER25453.1 - 0.084 12.2 0.0 0.92 8.8 0.0 2.1 2 0 0 2 2 2 0 Legume lectin domain BRF1 PF07741.8 EER25454.1 - 4.9 7.4 24.5 0.2 11.9 4.1 3.5 2 1 1 3 3 3 0 Brf1-like TBP-binding domain PRCC PF10253.4 EER25455.1 - 7.2e-45 153.9 2.1 7.2e-45 153.9 1.4 2.4 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DUF3723 PF12520.3 EER25455.1 - 0.032 12.7 0.5 0.045 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3723) Sigma70_r4 PF04545.11 EER25455.1 - 0.058 12.7 0.0 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 AAA_5 PF07728.9 EER25456.1 - 6.3e-128 421.2 0.0 1.3e-21 76.8 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EER25456.1 - 1.1e-27 96.2 0.0 7.3e-11 41.8 0.0 6.8 7 0 0 7 7 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EER25456.1 - 1.8e-26 92.9 1.5 0.00024 21.3 0.0 7.4 7 0 0 7 7 7 6 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER25456.1 - 2.3e-22 79.5 0.9 0.029 14.4 0.0 8.6 7 0 0 7 7 7 5 AAA domain AAA_16 PF13191.1 EER25456.1 - 5.2e-21 75.4 24.4 6.9e-05 22.8 0.1 9.0 9 1 0 9 9 7 5 AAA ATPase domain AAA_17 PF13207.1 EER25456.1 - 7.1e-19 68.8 0.0 0.0082 16.9 0.0 7.4 6 0 0 6 6 6 3 AAA domain Sigma54_activat PF00158.21 EER25456.1 - 1.5e-17 63.6 0.0 0.05 13.0 0.0 6.2 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_33 PF13671.1 EER25456.1 - 2.1e-17 63.3 0.0 0.02 14.7 0.0 7.3 6 2 0 6 6 6 4 AAA domain AAA_14 PF13173.1 EER25456.1 - 2.6e-17 62.9 0.0 0.00074 19.4 0.0 7.4 7 0 0 7 7 7 3 AAA domain Sigma54_activ_2 PF14532.1 EER25456.1 - 1e-15 57.9 1.0 0.039 14.0 0.1 7.1 7 0 0 7 7 6 2 Sigma-54 interaction domain UPF0079 PF02367.12 EER25456.1 - 2.9e-13 49.5 2.2 0.09 12.4 0.0 6.3 6 0 0 6 6 5 3 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EER25456.1 - 3.2e-13 49.2 0.2 0.35 9.9 0.0 7.0 6 0 0 6 6 6 3 Zeta toxin NACHT PF05729.7 EER25456.1 - 1.3e-12 47.7 10.6 0.081 12.5 0.0 6.7 7 0 0 7 7 6 4 NACHT domain AAA_18 PF13238.1 EER25456.1 - 2.3e-12 47.3 11.7 0.026 14.8 0.0 7.5 7 0 0 7 7 6 3 AAA domain RNA_helicase PF00910.17 EER25456.1 - 3.2e-12 46.5 1.5 2.9 8.1 0.0 6.9 6 0 0 6 6 6 1 RNA helicase Miro PF08477.8 EER25456.1 - 3.5e-12 46.8 0.7 0.99 9.9 0.0 6.9 6 0 0 6 6 6 1 Miro-like protein DUF258 PF03193.11 EER25456.1 - 4.7e-12 45.4 5.4 0.032 13.4 0.0 5.8 6 0 0 6 6 6 3 Protein of unknown function, DUF258 AAA_19 PF13245.1 EER25456.1 - 6e-12 45.1 6.4 0.057 13.1 0.1 6.8 6 0 0 6 6 6 3 Part of AAA domain ABC_tran PF00005.22 EER25456.1 - 9.7e-12 45.3 12.7 0.11 12.8 0.0 7.4 7 1 0 7 7 6 3 ABC transporter Mg_chelatase PF01078.16 EER25456.1 - 1.3e-10 40.8 3.9 0.85 8.7 0.0 8.6 8 2 0 9 9 9 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EER25456.1 - 2.2e-10 40.6 0.3 4.2 6.9 0.0 6.7 6 0 0 6 6 6 0 Archaeal ATPase AAA_29 PF13555.1 EER25456.1 - 9.3e-10 37.8 1.0 2.2 7.8 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain MobB PF03205.9 EER25456.1 - 9.2e-09 35.1 1.3 2.9 7.5 0.0 6.5 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EER25456.1 - 3.3e-08 32.7 4.5 0.069 12.0 0.0 5.4 6 0 0 6 6 5 2 Type II/IV secretion system protein RuvB_N PF05496.7 EER25456.1 - 3.4e-08 32.8 1.3 0.65 9.0 0.0 5.3 5 0 0 5 5 5 2 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EER25456.1 - 4.3e-08 32.7 0.1 1.4 8.2 0.0 5.9 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_25 PF13481.1 EER25456.1 - 1.1e-07 31.4 4.6 1.2 8.4 0.0 6.3 5 0 0 5 5 5 1 AAA domain SRP54 PF00448.17 EER25456.1 - 1.2e-07 31.3 5.7 1.2 8.5 0.0 5.9 6 0 0 6 6 6 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EER25456.1 - 1.4e-07 31.1 2.2 0.08 12.4 0.0 6.0 6 0 0 6 6 6 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.2 EER25456.1 - 6.1e-07 28.7 1.0 1.1 8.3 0.0 5.2 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 AAA_28 PF13521.1 EER25456.1 - 6.9e-07 29.3 9.0 0.39 10.6 0.1 6.4 6 0 0 6 6 6 2 AAA domain Bac_DnaA PF00308.13 EER25456.1 - 4.6e-06 26.4 0.1 1.3 8.6 0.0 4.5 4 0 0 4 4 4 1 Bacterial dnaA protein MMR_HSR1 PF01926.18 EER25456.1 - 6.6e-05 22.8 2.8 18 5.2 0.0 6.0 6 0 0 6 6 6 0 50S ribosome-binding GTPase Rad17 PF03215.10 EER25456.1 - 7.9e-05 21.5 0.4 0.26 9.9 0.0 4.4 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein ResIII PF04851.10 EER25456.1 - 0.00014 21.7 0.0 3.2 7.5 0.0 5.1 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EER25456.1 - 0.00062 19.4 2.6 7.5 6.0 0.0 5.7 6 0 0 6 6 6 0 AAA domain MCM PF00493.18 EER25456.1 - 0.00077 18.3 0.2 5.1 5.8 0.0 4.2 4 0 0 4 4 4 0 MCM2/3/5 family TIP49 PF06068.8 EER25456.1 - 0.0021 16.8 2.7 1.2 7.8 0.0 4.4 5 0 0 5 5 5 1 TIP49 C-terminus CPT PF07931.7 EER25456.1 - 0.0031 17.1 0.3 0.7 9.5 0.0 3.9 4 1 0 4 4 2 1 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EER25456.1 - 0.0034 17.1 7.1 2.2 7.9 0.0 5.0 5 0 0 5 5 4 1 NTPase KaiC PF06745.8 EER25456.1 - 0.0041 16.2 0.1 6.4 5.8 0.0 3.7 4 0 0 4 4 4 0 KaiC PhoH PF02562.11 EER25456.1 - 0.0075 15.5 0.7 2.9 7.0 0.0 4.1 4 0 0 4 4 4 1 PhoH-like protein AAA_6 PF12774.2 EER25456.1 - 0.0082 15.6 0.0 57 3.1 0.0 6.3 7 2 0 7 7 7 0 Hydrolytic ATP binding site of dynein motor region D1 cobW PF02492.14 EER25456.1 - 0.079 12.4 7.8 13 5.1 0.1 5.5 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EER25456.1 - 0.12 11.9 7.6 34 3.8 0.0 5.5 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EER25456.1 - 0.18 11.0 0.9 35 3.6 0.0 4.1 4 0 0 4 4 4 0 Ferrous iron transport protein B Ras PF00071.17 EER25456.1 - 0.31 10.4 3.8 28 4.0 0.0 4.5 5 0 0 5 5 5 0 Ras family Voltage_CLC PF00654.15 EER25457.1 - 1.3e-89 300.7 23.3 1.3e-89 300.7 16.2 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EER25457.1 - 2.1e-05 24.2 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain P5CR_dimer PF14748.1 EER25458.1 - 4.1e-32 110.3 2.8 6.8e-32 109.6 1.9 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EER25458.1 - 7.9e-11 42.2 0.2 3.9e-08 33.5 0.0 2.7 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent GHMP_kinases_C PF08544.8 EER25458.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 GHMP kinases C terminal CTK3 PF12243.3 EER25459.1 - 1.1e-54 183.8 0.2 1.5e-54 183.4 0.1 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EER25459.1 - 1.1e-20 73.3 7.8 3e-20 71.9 5.4 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CARD PF00619.16 EER25459.1 - 0.044 13.6 0.3 0.19 11.5 0.0 2.2 2 1 0 2 2 2 0 Caspase recruitment domain U3_snoRNA_assoc PF08297.6 EER25460.1 - 3.9e-14 52.6 0.2 3.9e-14 52.6 0.1 3.4 2 1 0 2 2 2 1 U3 snoRNA associated EBV-NA3 PF05009.7 EER25460.1 - 0.025 13.8 4.0 0.049 12.8 2.7 1.4 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Borrelia_P83 PF05262.6 EER25460.1 - 0.18 10.0 13.8 0.25 9.5 9.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Pox_RNA_Pol_19 PF05320.7 EER25460.1 - 8.4 6.1 11.4 19 4.9 7.9 1.5 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Tombus_P33 PF08500.5 EER25460.1 - 9.1 6.0 7.3 7.5 6.2 3.6 1.9 2 0 0 2 2 2 0 Tombusvirus p33 Abhydrolase_6 PF12697.2 EER25461.1 - 2.4e-23 83.1 0.1 2.9e-23 82.9 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER25461.1 - 6.3e-07 29.2 0.0 1.2e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF155 PF02582.9 EER25462.1 - 1.5e-51 174.7 0.5 2.6e-51 174.0 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.14 EER25463.1 - 0.096 12.9 0.0 0.24 11.6 0.0 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box Menin PF05053.8 EER25463.1 - 1.5 6.8 7.7 2.1 6.4 3.4 1.9 1 1 0 2 2 2 0 Menin WD40 PF00400.27 EER25464.1 - 4.3e-52 172.2 22.8 7.2e-09 35.2 0.2 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EER25464.1 - 1.6e-11 43.7 0.5 3.3e-11 42.7 0.4 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EER25464.1 - 1.4e-08 33.3 5.8 0.016 13.3 0.6 3.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 F-box PF00646.28 EER25464.1 - 8.4e-05 22.1 0.8 0.00025 20.6 0.5 1.9 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 EER25464.1 - 0.00015 20.6 0.3 0.0029 16.4 0.0 2.8 1 1 0 2 2 2 1 Nup133 N terminal like PQQ_2 PF13360.1 EER25464.1 - 0.015 14.7 4.2 0.5 9.7 0.1 3.3 1 1 1 3 3 3 0 PQQ-like domain PQQ_3 PF13570.1 EER25464.1 - 0.14 12.4 6.0 48 4.4 0.0 5.5 4 2 2 6 6 6 0 PQQ-like domain Zip PF02535.17 EER25465.1 - 2.1e-36 125.5 24.5 2.6e-33 115.3 17.0 3.3 1 1 0 1 1 1 1 ZIP Zinc transporter Transp_cyt_pur PF02133.10 EER25466.1 - 3.8e-100 335.5 37.4 4.3e-100 335.3 25.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CcmD PF04995.9 EER25466.1 - 0.32 10.7 0.0 0.32 10.7 0.0 2.5 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF917 PF06032.7 EER25467.1 - 9.3e-121 402.6 0.1 8.5e-118 392.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EER25467.1 - 4.2e-49 167.1 11.4 3e-48 164.3 4.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EER25467.1 - 1.7e-32 112.3 2.7 2.2e-28 98.9 0.0 3.7 3 0 0 3 3 3 3 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EER25467.1 - 1.3e-05 23.7 1.0 0.032 12.5 0.4 2.5 2 0 0 2 2 2 2 MutL protein BcrAD_BadFG PF01869.15 EER25467.1 - 0.017 14.4 0.6 0.017 14.4 0.4 2.8 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family Hat1_N PF10394.4 EER25468.1 - 1.1e-42 145.7 0.1 2.3e-42 144.7 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Adaptin_binding PF10199.4 EER25469.1 - 0.027 14.7 0.9 0.045 14.0 0.6 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF4391 PF14335.1 EER25469.1 - 0.11 11.8 0.4 0.17 11.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) LSM PF01423.17 EER25470.1 - 1.2e-16 60.0 0.0 1.8e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EER25470.1 - 0.078 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain API5 PF05918.6 EER25470.1 - 9.1 4.6 14.2 10 4.4 9.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DSPc PF00782.15 EER25471.1 - 2e-10 40.3 0.0 3.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EER25471.1 - 0.0059 15.9 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EER25471.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EER25471.1 - 0.033 14.2 0.1 0.068 13.2 0.1 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate HTH_32 PF13565.1 EER25472.1 - 1.3e-05 25.8 0.0 3.7e-05 24.4 0.0 1.8 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.1 EER25472.1 - 0.00032 20.7 0.0 0.00038 20.5 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_26 PF13443.1 EER25472.1 - 0.00092 19.3 0.3 0.55 10.4 0.1 2.2 2 0 0 2 2 2 2 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.1 EER25472.1 - 0.0049 16.4 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_31 PF13560.1 EER25472.1 - 0.0067 16.6 0.1 0.035 14.2 0.0 2.1 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_Mga PF08280.6 EER25472.1 - 0.018 14.8 0.0 0.6 9.9 0.0 2.3 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain GerE PF00196.14 EER25472.1 - 0.084 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family DUF1233 PF06806.7 EER25472.1 - 0.087 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative excisionase (DUF1233) PAX PF00292.13 EER25472.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 'Paired box' domain HTH_Crp_2 PF13545.1 EER25472.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PPR_2 PF13041.1 EER25473.1 - 3.7e-16 58.8 0.0 0.00018 21.4 0.0 7.7 6 3 3 9 9 9 2 PPR repeat family PPR_3 PF13812.1 EER25473.1 - 1.2e-14 53.3 5.3 0.052 13.8 0.0 9.0 10 0 0 10 10 10 5 Pentatricopeptide repeat domain PPR PF01535.15 EER25473.1 - 5.2e-13 48.0 4.3 0.48 10.5 0.1 8.1 8 0 0 8 8 8 4 PPR repeat Umbravirus_LDM PF04817.7 EER25473.1 - 0.0098 15.0 1.1 0.02 14.0 0.8 1.4 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family PLA2_B PF01735.13 EER25474.1 - 2.8e-23 81.8 0.0 4.7e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Exo70 PF03081.10 EER25475.1 - 6.7e-74 248.8 0.0 9.8e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Exo70 exocyst complex subunit APH PF01636.18 EER25477.1 - 1.7e-15 57.4 0.0 4.4e-15 56.0 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER25477.1 - 2.8e-05 23.7 0.9 4.3e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase BCDHK_Adom3 PF10436.4 EER25478.1 - 9.3e-71 236.6 0.0 1.3e-70 236.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EER25478.1 - 2.8e-19 68.8 0.0 1.1e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EER25478.1 - 0.0012 18.5 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VSP PF03302.8 EER25479.1 - 0.0002 20.1 0.2 0.0002 20.1 0.1 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein Mid2 PF04478.7 EER25479.1 - 0.0038 16.6 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Podoplanin PF05808.6 EER25479.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Podoplanin SKN1 PF03935.10 EER25480.1 - 9.7e-229 759.6 0.1 1.1e-228 759.4 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Na_H_Exchanger PF00999.16 EER25481.1 - 7.5e-36 123.4 12.0 9.6e-36 123.1 8.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EER25481.1 - 0.013 15.4 0.9 0.048 13.6 0.1 2.4 2 0 0 2 2 2 0 YrhC-like protein DUF3267 PF11667.3 EER25481.1 - 2.4 8.3 8.3 0.11 12.7 1.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3267) DUF3040 PF11239.3 EER25481.1 - 4.9 7.2 5.5 6.3 6.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Ribosomal_L3 PF00297.17 EER25483.1 - 1.5e-118 394.9 5.6 1.8e-118 394.6 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 TPR_1 PF00515.23 EER25484.1 - 2.1e-53 175.8 34.8 4.1e-08 32.5 0.0 10.9 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EER25484.1 - 6.7e-47 157.0 22.7 3.7e-11 42.5 0.9 6.6 2 2 2 6 6 6 6 TPR repeat TPR_2 PF07719.12 EER25484.1 - 1e-46 153.0 26.4 1.1e-05 24.9 0.0 10.6 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 EER25484.1 - 7.4e-37 122.3 24.3 6.3e-06 25.5 0.0 10.3 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EER25484.1 - 3.9e-33 113.4 17.3 1.4e-07 31.9 0.1 8.1 5 2 4 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 EER25484.1 - 1e-30 105.4 21.8 1.1e-06 28.4 0.4 7.4 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 EER25484.1 - 5.9e-27 91.5 19.7 0.00098 19.1 0.1 11.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_14 PF13428.1 EER25484.1 - 1.4e-25 87.4 15.6 0.00038 20.8 0.0 9.7 5 3 5 10 10 9 7 Tetratricopeptide repeat TPR_19 PF14559.1 EER25484.1 - 6.8e-23 80.7 15.3 0.00072 19.8 0.2 7.2 5 2 1 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EER25484.1 - 5.6e-22 75.7 13.4 0.0051 16.5 0.0 9.6 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 EER25484.1 - 2.1e-20 71.7 17.2 0.0053 17.1 0.0 10.2 10 0 0 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 EER25484.1 - 6.1e-13 48.7 12.9 4.8e-08 33.0 2.5 4.3 4 2 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EER25484.1 - 9.9e-13 47.7 12.4 0.0032 17.2 0.1 7.3 1 1 8 9 9 9 5 Tetratricopeptide repeat TPR_15 PF13429.1 EER25484.1 - 1.5e-07 30.7 8.7 0.027 13.5 1.9 5.1 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 EER25484.1 - 0.00018 21.5 0.7 0.13 12.4 0.1 4.2 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_21 PF09976.4 EER25484.1 - 0.00023 21.1 10.6 0.38 10.6 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF2225 PF09986.4 EER25484.1 - 0.0036 16.8 3.0 0.14 11.5 0.0 3.2 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 EER25484.1 - 0.044 13.6 16.5 5.5 6.9 1.5 6.0 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EER25484.1 - 0.33 10.9 8.3 18 5.4 0.1 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat ChAPs PF09295.5 EER25484.1 - 0.76 8.4 2.1 7.1 5.2 0.2 2.7 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_3 PF07720.7 EER25484.1 - 8.4 6.3 17.2 46 3.9 0.0 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat NUC173 PF08161.7 EER25485.1 - 7.9e-77 257.1 0.0 9.2e-76 253.6 0.0 2.6 3 0 0 3 3 3 1 NUC173 domain Vps35 PF03635.12 EER25485.1 - 0.021 12.9 0.2 0.035 12.2 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 HEAT PF02985.17 EER25485.1 - 0.098 12.7 4.5 12 6.3 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.1 EER25485.1 - 0.83 9.9 11.2 0.88 9.8 0.3 5.0 5 1 0 5 5 5 0 HEAT repeats LSM PF01423.17 EER25486.1 - 3.5e-14 52.0 0.1 5e-14 51.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF605 PF04652.11 EER25486.1 - 7.3 5.8 6.3 9.9 5.4 4.4 1.2 1 0 0 1 1 1 0 Vta1 like Ribonuclease_3 PF00636.21 EER25487.1 - 4.5e-41 139.8 0.0 8.4e-20 71.3 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EER25487.1 - 3.5e-24 85.2 0.0 8.6e-13 48.3 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EER25487.1 - 1.3e-19 70.3 0.1 4.2e-19 68.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 EER25487.1 - 1e-17 63.6 0.0 3.1e-17 62.1 0.0 1.9 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EER25487.1 - 9.8e-15 54.1 0.1 3.5e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25487.1 - 1.2e-10 41.4 0.0 3.5e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Proteasome PF00227.21 EER25488.1 - 8.5e-58 194.7 0.0 2.1e-33 115.2 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EER25488.1 - 1.8e-11 43.1 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.13 EER25488.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RINGv PF12906.2 EER25489.1 - 2e-09 37.3 0.7 2e-09 37.3 0.5 2.2 2 0 0 2 2 2 1 RING-variant domain DUF2752 PF10825.3 EER25489.1 - 0.009 16.0 1.8 0.019 14.9 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) zf-RING_2 PF13639.1 EER25489.1 - 0.024 14.4 1.3 0.024 14.4 0.9 2.1 2 0 0 2 2 2 0 Ring finger domain DUF1206 PF06724.6 EER25489.1 - 0.19 11.4 2.3 0.47 10.2 1.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) DUF3951 PF13131.1 EER25489.1 - 6.7 6.5 8.6 0.4 10.4 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) Rubredoxin PF00301.15 EER25489.1 - 8.7 6.3 7.1 5.5 6.9 0.1 3.5 4 0 0 4 4 4 0 Rubredoxin Aldo_ket_red PF00248.16 EER25490.1 - 1.2e-40 139.1 0.0 1.3e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3422 PF11902.3 EER25491.1 - 0.025 13.4 0.7 0.031 13.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) FlgN PF05130.7 EER25491.1 - 0.083 13.1 0.4 0.083 13.1 0.3 1.8 2 0 0 2 2 2 0 FlgN protein Fungal_trans PF04082.13 EER25492.1 - 7.4e-14 51.2 0.2 1.9e-13 49.8 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER25492.1 - 0.0029 17.4 11.3 0.0029 17.4 7.8 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EER25494.1 - 1.3e-82 277.7 27.2 1.7e-82 277.4 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER25494.1 - 9.6e-14 50.8 30.0 9.6e-14 50.8 20.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_1 PF00300.17 EER25495.1 - 9.1e-25 87.5 0.0 1.6e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 EER25496.1 - 9e-78 260.3 0.0 1.3e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EER25496.1 - 3.6e-32 111.6 0.1 1.1e-31 110.1 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EER25496.1 - 1.4e-06 28.2 0.0 3.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EER25496.1 - 0.00085 18.6 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Vps39_2 PF10367.4 EER25497.1 - 1.4e-32 112.0 0.0 3.8e-32 110.7 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EER25497.1 - 3.1e-30 104.3 0.0 3.6e-29 100.9 0.0 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EER25497.1 - 5.2e-18 65.4 0.0 1.5e-17 63.8 0.0 1.7 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 EER25497.1 - 1.5e-07 31.1 1.0 6e-05 22.6 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS TPR_11 PF13414.1 EER25497.1 - 0.0004 19.9 2.7 0.68 9.6 0.0 4.6 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 EER25497.1 - 0.0033 18.0 0.1 37 5.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Gon7 PF08738.5 EER25498.1 - 3e-14 52.8 0.3 4.8e-14 52.1 0.2 1.3 1 0 0 1 1 1 1 Gon7 family APH PF01636.18 EER25499.1 - 1.3e-16 61.0 0.0 1.8e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER25499.1 - 0.00018 21.1 0.0 0.0003 20.4 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EER25499.1 - 0.018 14.1 0.0 0.25 10.3 0.0 2.1 1 1 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 EER25499.1 - 0.026 13.8 0.0 0.07 12.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EER25499.1 - 0.037 13.1 0.0 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Metallophos PF00149.23 EER25500.1 - 2.9e-11 43.1 8.1 6.7e-11 41.9 5.6 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER25500.1 - 1e-09 38.3 0.3 1.7e-09 37.7 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EER25500.1 - 0.026 13.6 0.0 0.081 12.0 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily DUF2204 PF09970.4 EER25501.1 - 1.9e-05 24.2 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) HbrB PF08539.6 EER25502.1 - 3.7e-50 169.8 0.0 5.5e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 HbrB-like K1377 PF15352.1 EER25503.1 - 0.088 10.7 0.0 0.12 10.3 0.0 1.0 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy Myb_DNA-bind_6 PF13921.1 EER25504.1 - 8.2e-06 25.8 1.1 0.072 13.2 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EER25504.1 - 0.011 16.3 2.7 0.077 13.6 0.2 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EER25504.1 - 0.29 11.0 5.4 2.4 8.0 0.4 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain AAA PF00004.24 EER25505.1 - 2.7e-16 59.9 0.0 6.9e-16 58.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EER25505.1 - 2.4e-05 23.9 0.1 7.7e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EER25505.1 - 0.0002 21.1 0.0 0.00061 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EER25505.1 - 0.0012 18.9 3.1 0.007 16.5 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EER25505.1 - 0.0026 17.7 0.2 0.016 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EER25505.1 - 0.067 13.0 0.1 0.067 13.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain Sec7 PF01369.15 EER25506.1 - 1e-59 201.4 0.0 3.4e-59 199.7 0.0 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EER25506.1 - 9.7e-55 184.5 5.5 9.7e-55 184.5 3.8 3.1 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EER25506.1 - 9.1e-32 108.4 7.0 4e-31 106.3 0.1 4.5 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 EER25507.1 - 2.6e-76 255.9 0.1 3.3e-76 255.6 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EER25507.1 - 6.8e-18 64.0 0.9 6.8e-18 64.0 0.6 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EER25507.1 - 6.7e-14 51.2 0.5 1.7e-13 49.9 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain V-SNARE_C PF12352.3 EER25509.1 - 7.2e-14 51.6 0.3 1.6e-13 50.5 0.2 1.6 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EER25509.1 - 0.004 16.8 0.0 0.0086 15.7 0.0 1.5 1 0 0 1 1 1 1 Sec20 Sigma70_r4 PF04545.11 EER25509.1 - 0.0049 16.1 0.3 0.012 14.8 0.2 1.7 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_DeoR PF08220.7 EER25509.1 - 0.018 14.5 0.1 0.66 9.5 0.0 2.3 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain TPR_MLP1_2 PF07926.7 EER25509.1 - 0.032 13.9 0.5 0.085 12.6 0.1 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Vps5 PF09325.5 EER25509.1 - 0.047 12.9 1.6 0.059 12.6 0.4 1.5 2 0 0 2 2 2 0 Vps5 C terminal like PDR_assoc PF08370.6 EER25509.1 - 0.1 12.1 0.2 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Ldh_1_C PF02866.13 EER25511.1 - 3.8e-44 150.4 0.0 6.8e-44 149.6 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EER25511.1 - 1.1e-42 145.1 0.0 1.9e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EER25511.1 - 0.0029 16.3 0.0 0.0041 15.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 EER25511.1 - 0.037 13.0 0.2 0.27 10.2 0.0 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 EER25511.1 - 0.046 13.0 0.1 2.8 7.2 0.1 2.5 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase NAD_binding_7 PF13241.1 EER25512.1 - 9.3e-33 112.5 0.1 1.6e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EER25512.1 - 1.4e-29 101.1 0.0 2.1e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EER25512.1 - 2.3e-15 55.2 0.0 4.3e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 EER25512.1 - 0.097 12.7 0.3 0.18 11.9 0.2 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EER25512.1 - 0.16 11.8 1.2 0.36 10.6 0.1 2.0 1 1 1 2 2 2 0 ThiF family Pribosyltran_N PF13793.1 EER25513.1 - 2.9e-44 149.4 0.1 1.2e-41 141.1 0.0 2.5 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EER25513.1 - 8.4e-36 123.4 0.2 1.2e-30 106.6 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EER25513.1 - 1.3e-08 34.6 0.1 4.2e-06 26.5 0.0 2.6 3 0 0 3 3 3 2 Phosphoribosyl transferase domain CbiJ PF02571.9 EER25513.1 - 0.036 13.4 0.0 0.08 12.2 0.0 1.5 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK Methyltransf_10 PF05971.7 EER25514.1 - 1.3e-63 214.9 0.0 4e-63 213.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EER25514.1 - 9.2e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER25514.1 - 3.3e-05 23.3 0.0 6.1e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EER25514.1 - 3.6e-05 24.2 0.0 8.7e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EER25514.1 - 0.00037 20.1 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF633 PF04816.7 EER25514.1 - 0.0005 19.4 0.0 0.00097 18.5 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF633) PrmA PF06325.8 EER25514.1 - 0.0023 17.0 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EER25514.1 - 0.0068 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER25514.1 - 0.016 14.8 0.0 0.05 13.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EER25514.1 - 0.017 13.8 0.0 0.029 13.0 0.0 1.3 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase UPF0020 PF01170.13 EER25514.1 - 0.038 13.5 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Complex1_LYR PF05347.10 EER25515.1 - 1.1e-09 37.8 0.6 2.4e-09 36.8 0.4 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EER25515.1 - 1.5e-08 34.6 0.8 3e-08 33.7 0.6 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Ank_4 PF13637.1 EER25516.1 - 3.7e-12 46.4 3.4 1.4e-10 41.3 0.3 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EER25516.1 - 9.2e-06 25.9 0.5 0.0014 18.9 0.3 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EER25516.1 - 0.00036 20.6 5.0 0.0015 18.6 0.2 3.3 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER25516.1 - 0.0017 18.4 2.9 0.28 11.5 0.2 3.9 4 0 0 4 4 4 1 Ankyrin repeat KilA-N PF04383.8 EER25516.1 - 0.0073 15.9 0.2 0.0073 15.9 0.1 2.7 3 1 0 3 3 3 1 KilA-N domain DUF2935 PF11155.3 EER25516.1 - 0.92 9.6 4.2 2.2 8.3 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Ank PF00023.25 EER25516.1 - 1.4 8.8 8.2 1.7 8.5 0.5 4.3 4 0 0 4 4 4 0 Ankyrin repeat TBPIP PF07106.8 EER25516.1 - 7.6 6.0 13.0 0.69 9.4 0.3 3.0 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rick_17kDa_Anti PF05433.10 EER25517.1 - 0.00029 20.4 23.8 0.0005 19.6 16.5 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain SR-25 PF10500.4 EER25517.1 - 0.0048 16.3 18.0 0.0065 15.9 12.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3824 PF12868.2 EER25517.1 - 0.01 16.7 2.6 0.01 16.7 1.8 3.6 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) Gly-zipper_OmpA PF13436.1 EER25517.1 - 0.017 14.8 9.6 0.044 13.4 6.7 1.7 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF755 PF05501.6 EER25517.1 - 0.049 13.6 24.3 0.084 12.9 16.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Gly-zipper_Omp PF13488.1 EER25517.1 - 0.14 11.7 18.3 0.35 10.5 12.7 1.7 1 0 0 1 1 1 0 Glycine zipper BLVR PF06375.6 EER25517.1 - 1.7 8.4 12.9 2.5 7.9 9.0 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) SelP_N PF04592.9 EER25517.1 - 6.1 6.1 8.3 9.4 5.5 5.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1275 PF06912.6 EER25518.1 - 8.5e-38 129.6 14.9 1.1e-37 129.3 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) adh_short PF00106.20 EER25519.1 - 3.8e-31 108.2 0.8 3.8e-31 108.2 0.6 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER25519.1 - 5e-31 108.3 0.0 5.8e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER25519.1 - 1.4e-12 47.6 0.9 1.8e-12 47.2 0.2 1.4 2 0 0 2 2 1 1 KR domain NAD_binding_10 PF13460.1 EER25519.1 - 9.2e-05 22.5 1.5 0.00064 19.7 1.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EER25519.1 - 0.0002 20.5 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EER25519.1 - 0.0035 16.8 1.6 0.041 13.4 0.4 2.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_26 PF13659.1 EER25519.1 - 0.0064 16.5 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EER25519.1 - 0.007 15.8 0.3 0.28 10.6 0.0 2.7 2 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 EER25519.1 - 0.012 14.8 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EER25519.1 - 0.026 13.5 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EER25519.1 - 0.035 13.7 0.3 0.056 13.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EER25519.1 - 0.052 13.3 0.2 0.097 12.4 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EER25519.1 - 0.073 13.1 0.2 0.13 12.3 0.2 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EER25519.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC_tran PF00005.22 EER25520.1 - 1.7e-47 161.1 0.1 3.3e-24 85.7 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EER25520.1 - 3.9e-17 63.1 0.9 1.1e-05 25.5 0.5 4.3 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 EER25520.1 - 1.9e-15 56.7 0.0 3.7e-06 26.3 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EER25520.1 - 1e-09 37.7 0.1 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EER25520.1 - 1.4e-09 38.6 4.0 4.4e-05 23.9 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EER25520.1 - 3.1e-07 31.2 0.0 0.0043 17.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EER25520.1 - 5.5e-07 28.9 0.0 0.0017 17.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EER25520.1 - 2.9e-06 26.9 0.1 0.21 11.0 0.0 3.8 4 1 1 5 5 5 2 AAA-like domain MMR_HSR1 PF01926.18 EER25520.1 - 3.3e-06 27.0 0.0 0.04 13.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EER25520.1 - 3.7e-06 26.9 0.0 0.044 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EER25520.1 - 3.8e-06 27.0 0.0 0.033 14.3 0.0 3.6 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EER25520.1 - 4.3e-06 26.8 0.3 0.7 9.8 0.0 4.3 4 0 0 4 4 4 2 AAA ATPase domain SbcCD_C PF13558.1 EER25520.1 - 5.7e-06 26.1 0.0 0.031 14.1 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EER25520.1 - 9.3e-06 25.9 0.3 0.095 13.0 0.0 3.2 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EER25520.1 - 1.3e-05 24.1 0.1 0.059 12.1 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 EER25520.1 - 1.6e-05 25.1 0.0 0.59 10.3 0.0 4.5 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) HEAT_2 PF13646.1 EER25520.1 - 2.2e-05 24.6 3.7 0.41 10.9 1.7 3.5 1 1 2 3 3 3 3 HEAT repeats Dynamin_N PF00350.18 EER25520.1 - 2.4e-05 24.2 0.0 0.0025 17.6 0.0 2.8 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.7 EER25520.1 - 3.8e-05 23.3 0.0 0.03 13.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 EER25520.1 - 7.5e-05 23.2 0.3 0.14 12.7 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein MobB PF03205.9 EER25520.1 - 8.1e-05 22.3 0.0 0.42 10.3 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EER25520.1 - 8.2e-05 22.5 0.0 0.63 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_13 PF13166.1 EER25520.1 - 8.6e-05 21.1 0.5 0.87 7.9 0.0 3.7 4 0 0 4 4 4 2 AAA domain PduV-EutP PF10662.4 EER25520.1 - 9.1e-05 21.9 0.0 0.22 11.0 0.0 2.9 3 0 0 3 3 2 2 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EER25520.1 - 0.00013 21.8 0.0 0.64 9.7 0.0 3.2 2 0 0 2 2 2 2 Domain of unknown function DUF87 RNA_helicase PF00910.17 EER25520.1 - 0.00014 21.9 0.0 0.58 10.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.1 EER25520.1 - 0.00056 19.0 9.4 0.48 9.4 0.0 4.5 3 2 2 5 5 5 1 AAA ATPase domain AAA_14 PF13173.1 EER25520.1 - 0.00074 19.4 0.0 2.8 7.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EER25520.1 - 0.0014 18.2 0.0 1.6 8.1 0.0 2.8 3 0 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 EER25520.1 - 0.0026 17.4 0.0 0.48 10.0 0.0 2.9 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 EER25520.1 - 0.0034 16.8 0.1 1.8 7.9 0.0 3.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain HEAT_EZ PF13513.1 EER25520.1 - 0.0037 17.7 9.1 9.7 6.8 0.7 5.8 5 1 2 7 7 4 0 HEAT-like repeat AAA_30 PF13604.1 EER25520.1 - 0.0044 16.6 0.0 3.6 7.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EER25520.1 - 0.0058 16.0 0.0 4 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain ParcG PF10274.4 EER25520.1 - 0.013 15.3 3.6 2.7 7.8 0.1 3.4 2 1 1 3 3 3 0 Parkin co-regulated protein Mg_chelatase PF01078.16 EER25520.1 - 0.019 14.1 0.8 5.6 6.0 0.0 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.12 EER25520.1 - 0.019 14.5 0.0 6.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EER25520.1 - 0.026 14.2 0.2 5.8 6.7 0.0 3.1 3 0 0 3 3 2 0 Part of AAA domain MutS_V PF00488.16 EER25520.1 - 0.028 13.8 0.1 1.3 8.3 0.0 2.5 2 0 0 2 2 2 0 MutS domain V T2SE PF00437.15 EER25520.1 - 0.029 13.2 0.6 2.8 6.7 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein NB-ARC PF00931.17 EER25520.1 - 0.036 12.9 0.0 0.53 9.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Cnd1 PF12717.2 EER25520.1 - 0.046 13.5 0.1 0.2 11.4 0.1 2.1 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EER25520.1 - 0.059 13.4 0.6 62 4.0 0.0 4.6 4 0 0 4 4 3 0 HEAT repeat AAA_5 PF07728.9 EER25520.1 - 0.095 12.4 0.0 15 5.2 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Mu-like_Pro PF10123.4 EER25520.1 - 8.7 5.7 10.4 0.77 9.1 3.7 1.8 2 0 0 2 2 1 0 Mu-like prophage I protein Pkinase PF00069.20 EER25521.1 - 3.6e-15 55.8 0.0 9.9e-15 54.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25521.1 - 0.0045 16.0 0.0 0.022 13.8 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase TPR_11 PF13414.1 EER25522.1 - 1e-10 41.1 4.7 1.7e-06 27.5 0.0 4.3 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 EER25522.1 - 3.9e-05 23.0 7.1 0.03 13.9 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER25522.1 - 0.0028 17.7 1.8 4.2 7.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EER25522.1 - 0.0035 17.0 1.9 3.7 7.5 0.5 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EER25522.1 - 0.0044 16.7 6.6 1.6 8.7 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EER25522.1 - 0.043 13.7 14.9 1.4 8.9 0.3 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EER25522.1 - 0.15 12.0 0.0 0.15 12.0 0.0 6.4 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF3889 PF13028.1 EER25522.1 - 0.26 10.9 0.6 0.56 9.9 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) TPR_16 PF13432.1 EER25522.1 - 0.26 11.9 0.0 0.1 13.3 0.4 5.2 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EER25522.1 - 1.1 9.1 8.5 1.3 8.9 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Shisa PF13908.1 EER25523.1 - 0.0044 17.2 2.8 0.0044 17.2 2.0 1.8 2 0 0 2 2 2 1 Wnt and FGF inhibitory regulator Tmemb_9 PF05434.6 EER25523.1 - 0.05 13.3 0.1 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 TMEM9 Ly49 PF08391.5 EER25523.1 - 0.059 13.5 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region VanY PF02557.12 EER25524.1 - 0.088 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase UCH PF00443.24 EER25525.1 - 3.1e-78 262.5 0.0 8.1e-78 261.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER25525.1 - 6.2e-17 61.9 0.0 2.1e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EER25525.1 - 8.7e-14 51.7 0.0 3.1e-13 49.9 0.0 2.1 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 EER25525.1 - 0.0021 17.5 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal PX PF00787.19 EER25526.1 - 6e-18 64.6 0.0 3.6e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EER25526.1 - 1.2e-11 44.3 10.9 1.5e-07 30.9 1.0 2.1 2 0 0 2 2 2 2 Vps5 C terminal like DUF2428 PF10350.4 EER25527.1 - 2.1e-68 230.1 0.0 3.8e-68 229.2 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EER25527.1 - 0.0021 18.0 2.5 12 6.2 0.1 4.8 5 0 0 5 5 5 2 HEAT repeat Tim17 PF02466.14 EER25528.1 - 7.8e-29 100.3 2.0 9.4e-29 100.0 1.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HTH_31 PF13560.1 EER25529.1 - 0.047 13.9 1.8 2.2 8.5 0.5 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain GLYCAM-1 PF05242.6 EER25529.1 - 0.068 13.1 0.1 3.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) Pkinase PF00069.20 EER25530.1 - 8.5e-49 166.0 0.0 1.1e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25530.1 - 3.8e-27 94.9 0.0 5.2e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER25530.1 - 0.0038 16.2 0.1 0.018 13.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like LVIVD PF08309.6 EER25531.1 - 1.5e-07 30.3 0.5 0.57 9.2 0.0 4.4 4 0 0 4 4 4 4 LVIVD repeat PQQ_3 PF13570.1 EER25531.1 - 0.0054 16.9 0.0 0.62 10.4 0.0 3.3 3 0 0 3 3 3 1 PQQ-like domain ILVD_EDD PF00920.16 EER25532.1 - 6.8e-204 678.1 0.7 7.9e-204 677.8 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family Lipase_3 PF01764.20 EER25533.1 - 4.2e-19 68.5 0.0 7.1e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EER25533.1 - 0.0085 15.9 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER25533.1 - 0.071 12.8 0.0 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EER25533.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EER25533.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein RAI16-like PF10257.4 EER25534.1 - 1e-86 291.0 0.0 1.9e-86 290.2 0.0 1.5 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein CBFD_NFYB_HMF PF00808.18 EER25535.1 - 3.1e-14 52.7 3.1 5.7e-14 51.9 2.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EER25535.1 - 3.1e-06 27.1 1.0 5.3e-06 26.4 0.7 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAT1 PF09770.4 EER25535.1 - 0.81 7.8 25.4 0.97 7.5 17.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C3HC4_3 PF13920.1 EER25536.1 - 0.0025 17.4 10.3 0.0044 16.6 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EER25536.1 - 1.2 8.9 5.6 2.2 8.1 3.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EER25536.1 - 8.4 6.2 11.7 14 5.5 8.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CTP_synth_N PF06418.9 EER25537.1 - 8.7e-97 323.4 0.2 1.2e-96 323.0 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EER25537.1 - 1.2e-53 181.3 0.0 2.1e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EER25537.1 - 5.3e-05 22.7 0.0 0.00055 19.4 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 DUF1900 PF08954.6 EER25538.1 - 4.8e-49 165.3 0.0 4.6e-48 162.2 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EER25538.1 - 1.7e-34 117.2 0.1 3.7e-34 116.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EER25538.1 - 1.1e-22 79.0 4.5 2.9e-06 26.9 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 EER25538.1 - 0.019 13.0 0.1 0.049 11.7 0.0 1.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TMF_DNA_bd PF12329.3 EER25538.1 - 0.054 13.3 0.7 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EER25538.1 - 0.35 11.2 3.2 0.34 11.3 0.6 2.0 2 0 0 2 2 2 0 SlyX p450 PF00067.17 EER25539.1 - 5.2e-55 186.7 0.0 1.1e-49 169.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Kinesin PF00225.18 EER25540.1 - 2.1e-103 345.5 0.2 2.1e-103 345.5 0.1 2.5 3 0 0 3 3 3 2 Kinesin motor domain Laminin_I PF06008.9 EER25540.1 - 0.0013 18.1 0.4 0.0013 18.1 0.3 3.6 2 1 0 3 3 3 1 Laminin Domain I T2SF PF00482.18 EER25540.1 - 0.42 10.5 1.6 13 5.7 0.1 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Filament PF00038.16 EER25540.1 - 8.8 5.6 45.5 1.2 8.5 9.6 4.0 2 1 2 4 4 4 0 Intermediate filament protein WEMBL PF05701.6 EER25540.1 - 9 4.6 40.9 0.7 8.2 23.5 2.2 2 1 0 2 2 2 0 Weak chloroplast movement under blue light Abhydrolase_6 PF12697.2 EER25541.1 - 1.9e-22 80.2 0.0 2.7e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER25541.1 - 8.2e-17 61.5 0.0 3.9e-15 56.0 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER25541.1 - 1.5e-06 28.0 0.0 5.5e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EER25541.1 - 0.046 13.9 0.0 0.078 13.1 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Sugar_tr PF00083.19 EER25542.1 - 3.9e-78 263.0 19.8 4.6e-78 262.8 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter RTA1 PF04479.8 EER25544.1 - 4.7e-55 186.5 13.0 7.2e-55 185.9 9.0 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 EER25545.1 - 7.2e-06 25.8 19.2 1.2e-05 25.1 13.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EER25545.1 - 0.0017 17.0 0.2 0.0028 16.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.2 EER25546.1 - 8.1e-37 125.4 2.4 4e-19 68.7 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EER25546.1 - 1.2e-31 106.9 8.5 2.3e-07 30.3 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EER25546.1 - 1.8e-29 101.5 7.1 8.7e-10 38.8 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER25546.1 - 4.6e-26 90.2 5.7 3.2e-10 39.9 0.1 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER25546.1 - 2.8e-24 82.7 1.1 1.1e-05 25.2 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Shigella_OspC PF06128.6 EER25546.1 - 0.0031 17.0 0.4 5.3 6.4 0.0 3.3 3 1 0 3 3 3 1 Shigella flexneri OspC protein CorA PF01544.13 EER25547.1 - 1.6e-06 27.4 3.4 2.2e-06 26.9 0.6 2.3 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein Fig1 PF12351.3 EER25548.1 - 6.1e-47 159.8 1.8 8.2e-47 159.4 1.3 1.1 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 GLTT PF01744.15 EER25548.1 - 0.027 13.8 0.3 0.06 12.7 0.2 1.6 1 0 0 1 1 1 0 GLTT repeat (6 copies) PGM_PMM_I PF02878.11 EER25549.1 - 1.2e-37 128.4 0.0 2.4e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EER25549.1 - 3.3e-24 85.1 0.1 6.8e-24 84.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EER25549.1 - 1.5e-13 50.7 0.0 3e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EER25549.1 - 1e-07 31.8 0.0 2.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain FA_desaturase PF00487.19 EER25550.1 - 1.8e-36 125.8 30.7 2.9e-36 125.2 21.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EER25550.1 - 1.7e-12 46.9 0.0 3.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CUE PF02845.11 EER25551.1 - 5.1e-08 32.2 0.0 1.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.17 EER25552.1 - 7e-29 99.5 0.5 8.4e-29 99.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ELYS PF13934.1 EER25554.1 - 2.4e-70 236.7 0.0 2.8e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 EER25555.1 - 4e-80 268.1 0.0 3.8e-78 261.7 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EER25555.1 - 1.6e-26 92.6 0.0 5.8e-26 90.8 0.0 2.1 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EER25555.1 - 3.8e-12 46.7 8.7 2.4e-05 24.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain Tropomyosin_1 PF12718.2 EER25555.1 - 0.00012 21.9 8.9 0.00012 21.9 6.2 7.3 3 2 4 7 7 7 2 Tropomyosin like Bacillus_HBL PF05791.6 EER25555.1 - 0.00028 20.3 3.3 0.00028 20.3 2.3 6.3 5 1 0 6 6 6 1 Bacillus haemolytic enterotoxin (HBL) AAA_29 PF13555.1 EER25555.1 - 0.0003 20.2 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CENP-F_leu_zip PF10473.4 EER25555.1 - 0.0016 18.3 8.4 0.0016 18.3 5.8 8.5 2 2 6 9 9 9 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CRCB PF02537.10 EER25555.1 - 0.29 11.0 0.0 0.53 10.1 0.0 1.3 1 0 0 1 1 1 0 CrcB-like protein Fungal_trans PF04082.13 EER25556.1 - 1.2e-15 57.1 0.3 2.8e-15 55.8 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER25556.1 - 4.8e-08 32.7 7.6 9.7e-08 31.7 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Suc_Fer-like PF06999.7 EER25557.1 - 3e-45 155.0 0.0 3.8e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Drc1-Sld2 PF11719.3 EER25558.1 - 4.9e-106 355.3 18.8 5.6e-106 355.1 13.1 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein zf-RING_2 PF13639.1 EER25559.1 - 4.6e-08 32.7 5.8 9.9e-08 31.6 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EER25559.1 - 1e-07 31.4 2.6 1.8e-07 30.6 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER25559.1 - 5.4e-07 29.5 5.1 1e-06 28.6 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER25559.1 - 1.1e-06 28.1 2.7 1.9e-06 27.3 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EER25559.1 - 0.00044 20.3 6.8 0.0013 18.7 4.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EER25559.1 - 2.9 7.6 8.4 0.25 11.1 2.1 2.0 2 0 0 2 2 2 0 zinc-RING finger domain DUF2410 PF10307.4 EER25560.1 - 1.5e-83 279.0 0.0 2e-83 278.6 0.0 1.1 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Fig1 PF12351.3 EER25561.1 - 9.9e-58 195.0 2.0 9.9e-58 195.0 1.4 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EER25561.1 - 5.6e-06 26.0 7.1 5.4e-05 22.8 4.9 2.2 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EER25561.1 - 0.0021 17.0 5.6 0.0021 17.0 3.9 1.4 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF2976 PF11190.3 EER25561.1 - 1.3 8.5 0.0 1.3 8.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) XPG_I PF00867.13 EER25562.1 - 2.1e-26 91.7 0.1 4.3e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EER25562.1 - 8.7e-21 74.0 0.0 2.5e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 EER25562.1 - 0.004 16.6 0.0 0.0066 15.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EER25562.1 - 0.095 12.9 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold OPT PF03169.10 EER25563.1 - 9.5e-162 539.6 52.7 1.1e-161 539.3 36.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF885 PF05960.6 EER25564.1 - 1.4e-53 182.9 0.0 1.9e-53 182.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) HHH_4 PF14490.1 EER25564.1 - 0.086 12.6 0.1 4.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain zf-rbx1 PF12678.2 EER25565.1 - 0.00038 20.5 10.7 0.0012 18.8 7.1 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger PSCyt3 PF07627.6 EER25565.1 - 0.02 14.7 0.4 0.12 12.2 0.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) zf-RING_2 PF13639.1 EER25565.1 - 0.041 13.7 17.1 0.023 14.5 10.0 2.1 2 1 0 2 2 2 0 Ring finger domain zf-Apc11 PF12861.2 EER25565.1 - 0.085 12.7 9.4 0.8 9.5 6.5 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EER25565.1 - 0.47 10.5 10.2 36 4.4 7.1 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER25565.1 - 0.52 10.0 11.5 4.5 7.0 8.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Tim17 PF02466.14 EER25568.1 - 7.9e-34 116.4 7.3 9.5e-34 116.1 5.1 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EER25568.1 - 0.11 12.3 0.0 0.25 11.1 0.0 1.6 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal MAM33 PF02330.11 EER25569.1 - 9.8e-33 113.6 0.3 3.3e-30 105.3 0.2 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein DNA_primase_S PF01896.14 EER25570.1 - 7.1e-54 181.5 0.1 1.3e-53 180.6 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MFS_1 PF07690.11 EER25571.1 - 1.5e-36 125.9 50.9 1.5e-36 125.9 35.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily DIOX_N PF14226.1 EER25572.1 - 4e-34 117.6 0.0 9.8e-32 109.9 0.0 2.3 2 0 0 2 2 2 2 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EER25572.1 - 4.5e-14 52.5 0.0 8.1e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3435 PF11917.3 EER25574.1 - 0.00074 18.3 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) RTC4 PF14474.1 EER25575.1 - 1.5e-22 79.8 0.0 1.7e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain DUF3050 PF11251.3 EER25575.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Pkinase PF00069.20 EER25576.1 - 0.019 14.1 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Sugar_tr PF00083.19 EER25578.1 - 1.5e-99 333.6 23.5 1.7e-99 333.4 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER25578.1 - 2.1e-21 76.0 33.8 8.6e-14 51.0 8.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fer4_13 PF13370.1 EER25579.1 - 0.77 10.1 2.7 15 6.0 0.0 3.5 2 2 1 3 3 3 0 4Fe-4S single cluster domain RNA_pol_N PF01194.12 EER25580.1 - 6.3e-13 48.5 0.1 6.6e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 EER25581.1 - 1.3e-05 24.9 5.5 0.011 15.5 0.1 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EER25581.1 - 0.00015 20.7 0.0 0.00051 18.9 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region Ribonuc_L-PSP PF01042.16 EER25582.1 - 1e-08 34.9 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Lactamase_B PF00753.22 EER25583.1 - 6.5e-16 58.5 2.9 9.7e-16 57.9 2.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EER25583.1 - 0.013 15.0 1.8 0.037 13.5 1.3 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain PGM_PMM_I PF02878.11 EER25583.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Pyr_redox_dim PF02852.17 EER25584.1 - 8.8e-40 135.1 0.1 3e-39 133.4 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EER25584.1 - 8.8e-39 133.4 15.5 2.1e-37 128.9 10.7 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER25584.1 - 6.1e-21 74.6 12.4 9.8e-20 70.7 1.1 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER25584.1 - 4.9e-12 46.3 0.1 1.1e-07 32.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EER25584.1 - 2.3e-10 40.1 7.8 4.1e-10 39.3 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EER25584.1 - 6.1e-10 38.5 10.7 6.1e-08 31.9 3.0 2.6 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EER25584.1 - 1.1e-08 35.0 6.5 0.00012 21.9 0.6 2.8 3 0 0 3 3 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EER25584.1 - 3.4e-07 29.5 0.2 0.0047 15.8 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EER25584.1 - 4.6e-07 29.0 3.9 4.6e-07 29.0 2.7 3.0 3 1 0 3 3 3 1 FAD binding domain DAO PF01266.19 EER25584.1 - 5.3e-07 28.8 18.6 0.0019 17.1 1.5 3.9 2 2 1 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.9 EER25584.1 - 5.9e-06 24.9 14.9 0.00072 18.1 1.5 4.1 4 0 0 4 4 4 3 HI0933-like protein Thi4 PF01946.12 EER25584.1 - 1.8e-05 23.9 1.4 1.8e-05 23.9 0.9 2.5 1 1 1 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EER25584.1 - 5.7e-05 22.7 2.9 0.015 14.9 0.0 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EER25584.1 - 0.00024 20.1 0.6 0.011 14.7 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EER25584.1 - 0.023 14.9 0.8 1 9.6 0.1 2.9 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EER25584.1 - 0.051 13.2 4.0 0.12 12.0 0.7 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EER25584.1 - 0.072 12.1 11.1 0.47 9.4 0.7 3.4 3 0 0 3 3 3 0 FAD binding domain FMO-like PF00743.14 EER25584.1 - 0.1 10.7 1.7 0.6 8.2 0.1 2.5 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like F420_oxidored PF03807.12 EER25584.1 - 0.54 10.7 3.6 18 5.8 0.1 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.9 EER25584.1 - 1.3 7.5 7.0 1 7.9 0.5 2.2 2 0 0 2 2 2 0 Tryptophan halogenase EI24 PF07264.6 EER25585.1 - 9e-08 31.8 9.0 2.6e-06 27.0 6.1 2.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF4112 PF13430.1 EER25585.1 - 0.018 14.9 0.0 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) Peptidase_S8 PF00082.17 EER25588.1 - 9.8e-50 169.2 10.9 1.3e-49 168.8 7.6 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER25588.1 - 1.2e-11 45.0 0.0 2.9e-11 43.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 Utp14 PF04615.8 EER25589.1 - 3.6 5.6 34.9 0.057 11.5 19.3 1.4 2 0 0 2 2 2 0 Utp14 protein GCIP PF13324.1 EER25590.1 - 0.071 12.3 1.6 0.19 10.9 0.6 1.8 1 1 0 2 2 2 0 Grap2 and cyclin-D-interacting GTPase_Cys_C PF12631.2 EER25590.1 - 0.09 13.2 0.6 6.6 7.2 0.0 2.8 2 1 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE Pex19 PF04614.7 EER25590.1 - 0.11 12.1 6.3 0.45 10.0 2.8 2.0 1 1 1 2 2 2 0 Pex19 protein family DUF3484 PF11983.3 EER25590.1 - 5.9 7.7 7.5 13 6.7 2.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) DGF-1_C PF11040.3 EER25591.1 - 5 7.0 6.0 2 8.3 2.3 1.7 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Dicty_REP PF05086.7 EER25591.1 - 5.1 4.7 9.4 5.4 4.6 6.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF2828 PF11443.3 EER25592.1 - 1.7e-152 508.3 4.5 3.3e-149 497.5 1.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) FA_desaturase PF00487.19 EER25593.1 - 2.3e-35 122.2 29.5 3.4e-35 121.7 20.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EER25593.1 - 1.6e-12 47.0 0.0 5.1e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain ATP_bind_3 PF01171.15 EER25593.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 PP-loop family FSH1 PF03959.8 EER25594.1 - 3.6e-31 108.2 0.0 4.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EER25594.1 - 2.2e-05 23.9 0.0 0.00034 20.1 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EER25594.1 - 0.049 13.5 0.5 7.9 6.2 0.1 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 EER25595.1 - 1.9e-69 233.9 0.0 5e-69 232.6 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EER25595.1 - 4.9e-60 202.2 1.9 1.6e-59 200.5 1.3 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EER25595.1 - 3.7e-53 180.6 0.8 7.2e-53 179.6 0.6 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EER25595.1 - 6.3e-53 180.1 0.2 3.8e-52 177.6 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain adh_short PF00106.20 EER25595.1 - 2.9e-44 150.9 1.9 2.3e-43 148.0 1.3 2.7 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EER25595.1 - 2.4e-39 133.8 0.7 1.1e-38 131.7 0.1 2.6 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EER25595.1 - 1.5e-19 69.7 0.3 4.8e-18 64.9 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER25595.1 - 6.2e-14 52.9 0.0 1.1e-12 48.8 0.0 3.1 3 0 0 3 3 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EER25595.1 - 3.5e-06 27.1 0.9 9.4e-06 25.8 0.6 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EER25595.1 - 0.00023 21.5 0.0 0.0023 18.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER25595.1 - 0.00066 19.4 0.0 0.0033 17.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain YjeF_N PF03853.10 EER25595.1 - 0.00078 19.0 0.1 0.68 9.5 0.0 2.7 2 0 0 2 2 2 2 YjeF-related protein N-terminus ADH_N PF08240.7 EER25595.1 - 0.0029 17.3 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Shikimate_DH PF01488.15 EER25595.1 - 0.053 13.6 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EER25596.1 - 1.3e-21 77.0 0.3 6.3e-21 74.8 0.2 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EER25596.1 - 0.013 15.8 0.7 0.013 15.8 0.5 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EER25596.1 - 0.049 12.4 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.19 EER25596.1 - 0.058 12.2 3.1 0.08 11.8 1.5 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase ketoacyl-synt PF00109.21 EER25597.1 - 7.9e-67 225.3 0.4 2e-66 224.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EER25597.1 - 3.2e-33 114.0 0.0 8e-33 112.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EER25597.1 - 3.6e-31 108.6 0.2 1.8e-30 106.3 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 EER25597.1 - 5.5e-28 97.5 0.0 1.6e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EER25597.1 - 7.1e-11 42.2 0.7 2.5e-10 40.4 0.3 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 EER25597.1 - 7.9e-08 32.0 0.0 2.7e-07 30.2 0.0 2.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EER25597.1 - 0.00017 20.6 0.0 0.00039 19.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.20 EER25597.1 - 0.00033 20.6 0.0 0.0013 18.6 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 EER25597.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Nif11 PF07862.6 EER25597.1 - 0.097 12.6 0.6 1.2 9.1 0.0 2.9 2 0 0 2 2 2 0 Nitrogen fixation protein of unknown function 3Beta_HSD PF01073.14 EER25597.1 - 0.11 11.1 0.0 7.9 5.0 0.0 2.7 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EER25597.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EER25597.1 - 0.21 10.4 0.0 0.42 9.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Amino_oxidase PF01593.19 EER25598.1 - 3.4e-47 161.5 1.4 1.1e-45 156.6 0.9 2.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EER25598.1 - 7e-15 54.8 0.5 1.4e-14 53.8 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EER25598.1 - 5.6e-12 45.4 0.0 1.6e-09 37.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 EER25598.1 - 1.6e-11 43.7 0.0 1.4e-08 34.0 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EER25598.1 - 1.6e-09 38.1 0.5 1.6e-05 25.0 0.2 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER25598.1 - 3.8e-08 32.7 0.0 6.2e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EER25598.1 - 5e-08 32.2 0.2 8.2e-08 31.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EER25598.1 - 1.1e-06 27.8 0.0 1.6e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EER25598.1 - 1.7e-06 26.7 0.0 2.4e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EER25598.1 - 1.4e-05 25.3 0.0 0.0018 18.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER25598.1 - 3.2e-05 23.8 0.1 7.1e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EER25598.1 - 8.7e-05 21.5 0.3 0.00019 20.4 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EER25598.1 - 0.0035 16.4 0.0 0.011 14.8 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EER25598.1 - 0.043 13.5 0.1 0.36 10.5 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans_2 PF11951.3 EER25599.1 - 3.1e-07 29.3 0.1 4.5e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT PF02985.17 EER25599.1 - 0.13 12.3 0.8 14 6.0 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat SnoaL PF07366.7 EER25600.1 - 0.00037 20.0 0.0 0.0007 19.1 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EER25600.1 - 0.0015 18.9 0.1 0.003 17.9 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like domain F-box-like PF12937.2 EER25601.1 - 0.026 14.2 2.0 0.026 14.2 1.4 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EER25601.1 - 0.14 11.8 1.5 0.42 10.3 0.7 2.2 2 0 0 2 2 2 0 F-box domain FmdA_AmdA PF03069.10 EER25602.1 - 7.2e-156 518.5 0.0 8.2e-156 518.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Pro_isomerase PF00160.16 EER25603.1 - 7.8e-47 159.3 0.7 1.2e-46 158.7 0.5 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EER25603.1 - 2.8e-10 39.7 6.5 2.7e-05 23.7 1.3 2.7 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EER25603.1 - 3.6e-07 29.6 5.3 2.4e-06 27.0 0.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER25603.1 - 1e-06 28.0 4.0 1.9e-06 27.1 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EER25603.1 - 0.0018 17.9 10.0 0.31 10.9 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EER25603.1 - 0.0077 16.7 5.0 0.081 13.5 0.9 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EER25603.1 - 0.011 15.9 0.2 0.55 10.5 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EER25603.1 - 0.039 13.8 6.0 0.11 12.5 2.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EER25603.1 - 0.047 13.5 1.1 0.23 11.3 0.3 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat UPF0150 PF03681.10 EER25603.1 - 1.4 8.6 3.6 5.7 6.6 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) TPR_16 PF13432.1 EER25603.1 - 5.6 7.7 10.9 3.5 8.4 1.0 3.4 3 1 1 4 4 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 EER25604.1 - 1.3e-44 151.7 0.0 1.4e-44 151.5 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 EER25605.1 - 2.7e-96 321.3 16.9 2.7e-96 321.3 11.7 1.5 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EER25605.1 - 5e-42 142.9 12.2 5e-42 142.9 8.4 2.2 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EER25605.1 - 0.0086 15.6 3.4 0.019 14.4 2.4 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Poty_PP PF08440.5 EER25605.1 - 0.018 14.1 0.8 0.037 13.0 0.5 1.5 1 0 0 1 1 1 0 Potyviridae polyprotein Cep57_MT_bd PF06657.8 EER25605.1 - 0.12 12.3 5.5 0.43 10.5 0.2 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 EER25605.1 - 0.6 10.4 7.5 2.5 8.4 0.4 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Ank_2 PF12796.2 EER25606.1 - 2.5e-56 187.9 15.7 1.1e-17 64.1 0.7 5.5 3 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EER25606.1 - 6e-52 170.9 22.5 1.6e-07 30.7 0.0 10.9 10 1 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 EER25606.1 - 1e-45 153.3 16.6 1.1e-09 38.4 0.1 10.0 3 1 7 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER25606.1 - 2e-41 135.8 11.0 7e-05 22.6 0.0 10.1 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 EER25606.1 - 8.5e-35 117.9 18.6 8.5e-10 38.5 0.2 6.7 4 1 4 8 8 8 7 Ankyrin repeats (many copies) F-box-like PF12937.2 EER25606.1 - 0.00052 19.6 0.0 0.00096 18.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like Carb_anhydrase PF00194.16 EER25607.1 - 1e-19 70.5 0.0 3.8e-19 68.6 0.0 1.9 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF1510 PF07423.6 EER25607.1 - 0.42 9.9 14.0 0.6 9.4 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EER25607.1 - 0.46 8.4 25.7 0.62 8.0 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EER25607.1 - 1.3 6.8 25.4 1.7 6.4 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 EER25607.1 - 3.2 5.3 8.4 4.1 4.9 5.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.8 EER25607.1 - 7.3 6.3 22.2 10 5.8 15.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_binding_1 PF01035.15 EER25608.1 - 4.7e-23 80.7 0.0 8.1e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Rubella_Capsid PF05750.6 EER25608.1 - 0.021 14.2 0.3 0.039 13.3 0.0 1.6 2 0 0 2 2 2 0 Rubella capsid protein Sugar_tr PF00083.19 EER25609.1 - 7.6e-87 291.7 21.8 8.6e-87 291.5 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER25609.1 - 1.1e-21 76.9 45.7 3.4e-17 62.1 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EER25609.1 - 0.056 13.4 7.9 2.8 8.0 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Rick_17kDa_Anti PF05433.10 EER25609.1 - 6.5 6.5 9.1 1.1 8.9 3.0 2.2 2 1 0 2 2 2 0 Glycine zipper 2TM domain Inp1 PF12634.2 EER25610.1 - 1.7e-33 115.3 0.0 2.6e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 DUF4551 PF15087.1 EER25610.1 - 0.22 9.8 0.3 0.33 9.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SRP14 PF02290.10 EER25611.1 - 3e-23 81.5 0.2 5.5e-23 80.6 0.2 1.4 1 1 0 1 1 1 1 Signal recognition particle 14kD protein Mucin PF01456.12 EER25611.1 - 0.35 10.6 13.8 0.51 10.1 9.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MIF4G PF02854.14 EER25612.1 - 3e-23 82.3 3.2 3.2e-23 82.2 0.2 2.4 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 EER25612.1 - 2.5e-18 65.8 0.0 2.5e-18 65.8 0.0 2.2 2 0 0 2 2 2 1 MA3 domain Hydrolase_like PF13242.1 EER25613.1 - 5.3e-08 32.4 0.0 1.2e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EER25613.1 - 0.00056 20.1 0.0 0.017 15.3 0.0 2.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase MRC1 PF09444.5 EER25615.1 - 3.6e-36 124.6 17.9 3.6e-36 124.6 12.4 5.3 4 1 1 5 5 5 1 MRC1-like domain SSP160 PF06933.6 EER25615.1 - 7.6 4.3 8.4 14 3.5 5.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Plus-3 PF03126.13 EER25616.1 - 6.7e-33 112.9 0.0 6.4e-32 109.8 0.0 2.2 2 0 0 2 2 2 1 Plus-3 domain COQ7 PF03232.8 EER25617.1 - 4.7e-62 208.4 0.0 5.8e-62 208.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EER25617.1 - 3.3e-05 24.2 0.1 0.0008 19.7 0.0 2.3 1 1 1 2 2 2 1 Rubrerythrin UPF0184 PF03670.8 EER25617.1 - 0.022 14.9 0.1 0.036 14.2 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) LMWPc PF01451.16 EER25618.1 - 1e-31 110.0 0.0 2.8e-31 108.6 0.0 1.6 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase FAD_binding_4 PF01565.18 EER25620.1 - 2.2e-18 66.0 2.5 3.3e-18 65.5 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EER25620.1 - 2.2e-05 24.2 0.3 7.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Chitin_synth_1 PF01644.12 EER25621.1 - 1.2e-80 269.0 0.1 1.8e-80 268.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EER25621.1 - 5.2e-31 106.1 0.0 9.7e-31 105.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EER25621.1 - 4.3e-23 81.5 4.0 7.6e-20 70.7 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EER25621.1 - 1.5e-08 34.6 0.0 1.1e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EER25621.1 - 3e-07 30.3 11.8 3e-07 30.3 8.2 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 CAP59_mtransfer PF11735.3 EER25623.1 - 1.9e-83 279.3 0.0 2.6e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 UPF0546 PF10639.4 EER25624.1 - 8.9e-37 125.3 2.2 9.5e-36 122.0 1.5 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EER25624.1 - 0.011 15.7 5.3 0.011 15.7 3.7 2.0 2 0 0 2 2 2 0 EamA-like transporter family EmrE PF13536.1 EER25624.1 - 0.019 15.1 4.0 0.019 15.1 2.7 1.7 2 1 0 2 2 2 0 Multidrug resistance efflux transporter TPT PF03151.11 EER25624.1 - 0.044 13.4 5.3 0.11 12.0 3.5 1.9 1 1 1 2 2 2 0 Triose-phosphate Transporter family DUF1211 PF06736.6 EER25624.1 - 0.11 12.6 0.3 0.29 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1211) HNH_2 PF13391.1 EER25625.1 - 8.1e-12 44.7 0.0 1.8e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Helicase_C_3 PF13625.1 EER25625.1 - 0.055 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Sulfate_transp PF00916.15 EER25626.1 - 5.1e-08 32.2 2.5 5.1e-08 32.2 1.7 2.6 3 0 0 3 3 3 1 Sulfate transporter family Pox_A14 PF05767.7 EER25626.1 - 3.7 7.5 7.6 12 5.9 0.2 3.7 2 2 1 3 3 3 0 Poxvirus virion envelope protein A14 PhyH PF05721.8 EER25627.1 - 1.8e-40 139.2 0.0 2.7e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) UTP15_C PF09384.5 EER25628.1 - 2.7e-52 176.4 2.0 4.3e-52 175.7 0.3 1.9 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.27 EER25628.1 - 6e-26 89.3 3.9 2.3e-07 30.4 0.3 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EER25628.1 - 0.00022 20.7 0.9 0.0011 18.5 0.1 2.2 2 1 1 3 3 3 1 PQQ-like domain CPSF_A PF03178.10 EER25628.1 - 0.0045 16.1 0.0 0.099 11.7 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region Nucleoporin_N PF08801.6 EER25628.1 - 0.037 12.7 0.1 0.15 10.7 0.0 1.8 1 1 1 2 2 2 0 Nup133 N terminal like C2 PF00168.25 EER25629.1 - 5.2e-12 45.4 0.1 1.1e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 C2 domain AAA_12 PF13087.1 EER25630.1 - 1.7e-30 105.9 0.0 2.6e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EER25630.1 - 1.6e-20 73.6 0.5 2.7e-19 69.6 0.2 2.9 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EER25630.1 - 8.8e-08 31.8 0.0 3.5e-07 29.8 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain UvrD-helicase PF00580.16 EER25630.1 - 0.00023 20.5 0.0 0.0021 17.4 0.0 2.0 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 EER25630.1 - 0.00061 19.4 0.0 0.0093 15.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain Viral_helicase1 PF01443.13 EER25630.1 - 0.01 15.3 0.1 0.18 11.2 0.0 2.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase UvrD_C PF13361.1 EER25630.1 - 0.018 14.4 0.0 1.3 8.4 0.0 2.4 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 EER25630.1 - 0.028 14.2 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_L22 PF00237.14 EER25632.1 - 2.6e-14 53.0 3.6 1.8e-07 31.0 0.3 2.7 2 1 1 3 3 3 2 Ribosomal protein L22p/L17e RRM_1 PF00076.17 EER25633.1 - 1.6e-53 178.2 0.0 1.9e-17 62.6 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER25633.1 - 1.1e-44 150.1 0.0 2.1e-13 50.0 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25633.1 - 2.7e-22 78.3 0.0 5.7e-05 22.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER25633.1 - 1.7e-07 30.9 0.0 0.095 12.4 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EER25633.1 - 0.0002 20.6 0.5 0.00069 18.9 0.4 2.0 1 0 0 1 1 1 1 Lsm interaction motif RNA_bind PF08675.6 EER25633.1 - 0.003 17.4 0.1 0.59 10.1 0.0 3.5 4 0 0 4 4 4 1 RNA binding domain Nup35_RRM PF05172.8 EER25633.1 - 0.063 13.0 0.0 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.1 EER25633.1 - 0.85 10.4 7.4 37 5.3 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF4271 PF14093.1 EER25634.1 - 0.0047 16.6 3.4 0.0066 16.1 2.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) MFS_1 PF07690.11 EER25634.1 - 0.055 12.1 5.1 0.069 11.8 3.5 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily DctQ PF04290.7 EER25634.1 - 0.1 12.3 4.8 0.19 11.5 3.4 1.5 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component ABC2_membrane_4 PF12730.2 EER25634.1 - 1.2 8.2 9.1 9.4 5.3 6.5 1.9 1 1 1 2 2 2 0 ABC-2 family transporter protein ABC2_membrane_3 PF12698.2 EER25634.1 - 1.5 7.8 6.3 1.9 7.4 4.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2232 PF09991.4 EER25634.1 - 1.9 7.4 8.2 1.1 8.2 3.7 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Oxidored_q2 PF00420.19 EER25634.1 - 2.2 7.9 7.7 20 4.8 3.1 2.1 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF805 PF05656.9 EER25634.1 - 6.8 6.5 7.6 16 5.3 5.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF805) BTB PF00651.26 EER25635.1 - 4.6e-12 45.9 0.0 7.9e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.11 EER25636.1 - 3.9e-39 134.3 48.1 6.3e-39 133.6 29.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_1 PF00300.17 EER25637.1 - 3.4e-18 66.2 0.0 4.6e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FAD_binding_4 PF01565.18 EER25638.1 - 8.3e-20 70.6 0.1 1.5e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EER25638.1 - 0.11 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like MARVEL PF01284.18 EER25641.1 - 2.9e-28 98.4 5.8 3.7e-28 98.1 4.0 1.0 1 0 0 1 1 1 1 Membrane-associating domain Acyl_transf_3 PF01757.17 EER25641.1 - 0.038 12.8 8.5 0.068 11.9 2.0 2.1 2 0 0 2 2 2 0 Acyltransferase family Pkinase PF00069.20 EER25642.1 - 1.8e-72 243.6 0.0 2.8e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25642.1 - 1.2e-36 126.1 0.0 1.9e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EER25642.1 - 8.7e-10 38.6 0.0 1.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EER25642.1 - 2.8e-07 29.7 0.0 5e-06 25.6 0.0 2.2 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EER25642.1 - 0.00012 21.4 0.2 0.00025 20.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EER25642.1 - 0.011 14.3 0.1 0.017 13.7 0.1 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EER25642.1 - 0.039 13.6 0.1 0.12 12.0 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EER25642.1 - 0.07 12.1 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRELI PF04707.9 EER25643.1 - 3.8e-25 88.2 0.0 2.1e-21 76.1 0.0 2.5 2 1 0 2 2 2 2 PRELI-like family TPR_11 PF13414.1 EER25644.1 - 1.4e-52 175.2 53.6 4.6e-13 48.6 0.5 7.3 2 2 6 9 9 9 9 TPR repeat TPR_1 PF00515.23 EER25644.1 - 9e-39 129.5 40.8 1.3e-06 27.7 0.1 11.6 10 1 1 11 11 11 11 Tetratricopeptide repeat TPR_2 PF07719.12 EER25644.1 - 3.8e-37 123.1 37.4 1.5e-05 24.5 0.1 11.5 10 1 1 11 11 11 9 Tetratricopeptide repeat TPR_16 PF13432.1 EER25644.1 - 1.8e-23 82.5 36.0 2.7e-07 31.0 1.7 7.2 7 1 1 8 8 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EER25644.1 - 3.3e-23 81.4 35.6 4.4e-08 32.9 0.1 7.7 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EER25644.1 - 6.1e-16 57.2 22.3 0.067 13.4 0.1 9.6 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EER25644.1 - 1.6e-15 55.6 27.8 0.0053 16.4 0.2 10.2 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EER25644.1 - 1.1e-14 53.5 26.7 0.014 15.9 0.4 10.4 4 3 6 11 11 9 6 Tetratricopeptide repeat TPR_7 PF13176.1 EER25644.1 - 1.6e-12 46.2 25.0 0.014 15.1 0.3 9.9 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 EER25644.1 - 2.6e-12 46.8 31.1 8e-06 26.1 0.9 7.1 4 1 2 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EER25644.1 - 1.2e-11 44.5 24.4 0.0012 18.9 0.7 5.6 3 1 3 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EER25644.1 - 2.3e-11 43.3 19.2 6.6e-06 25.8 0.2 7.1 4 2 4 8 8 8 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EER25644.1 - 1.3e-05 24.3 9.8 0.032 13.4 0.1 6.4 6 0 0 6 6 6 1 SHNi-TPR TPR_6 PF13174.1 EER25644.1 - 0.00061 20.0 26.4 1 9.9 0.0 8.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 EER25644.1 - 0.0072 16.2 19.0 0.42 10.6 0.7 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat MAS20 PF02064.10 EER25644.1 - 0.029 14.2 4.6 7.1 6.5 0.9 4.1 3 2 1 4 4 4 0 MAS20 protein import receptor GPCR_chapero_1 PF11904.3 EER25644.1 - 0.041 13.0 1.2 0.078 12.1 0.8 1.4 1 0 0 1 1 1 0 GPCR-chaperone NARP1 PF12569.3 EER25644.1 - 0.042 12.6 30.4 0.051 12.3 3.7 4.5 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 PPR_3 PF13812.1 EER25644.1 - 0.13 12.5 0.3 40 4.8 0.0 4.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Sel1 PF08238.7 EER25644.1 - 0.14 12.8 12.9 1.1 10.0 0.2 4.8 4 0 0 4 4 4 0 Sel1 repeat SPOUT_MTase PF02590.12 EER25644.1 - 0.63 9.7 5.2 0.81 9.3 0.0 3.0 3 0 0 3 3 2 0 Predicted SPOUT methyltransferase TPR_3 PF07720.7 EER25644.1 - 1.1 9.1 13.7 16 5.4 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EER25644.1 - 1.1 9.8 9.8 38 5.1 0.1 5.6 6 0 0 6 6 4 0 Tetratricopeptide repeat Aminotran_4 PF01063.14 EER25645.1 - 7.5e-32 110.6 0.0 9e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV FHA PF00498.21 EER25647.1 - 5.5e-14 52.0 0.0 1e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Sec1 PF00995.18 EER25648.1 - 3.4e-153 511.2 0.0 3.9e-153 511.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Chordopox_L2 PF05803.7 EER25649.1 - 0.058 13.0 0.1 0.094 12.3 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus L2 protein T2SE_Nter PF05157.10 EER25649.1 - 0.92 9.5 4.0 6.1 6.9 2.8 2.1 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein E, N-terminal domain zf-CCCH PF00642.19 EER25650.1 - 0.0022 17.6 0.6 0.0036 16.9 0.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) GTP_EFTU PF00009.22 EER25651.1 - 1.6e-48 164.6 0.0 2.5e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EER25651.1 - 1.8e-38 130.7 4.5 3e-38 130.0 3.1 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EER25651.1 - 1.8e-18 66.1 0.0 3.4e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EER25651.1 - 2.2e-07 30.8 0.2 5.9e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 EER25651.1 - 7.3e-06 25.4 0.0 5.9e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EER25651.1 - 7.2e-05 22.7 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EER25651.1 - 0.00011 21.9 0.0 0.00032 20.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II SRPRB PF09439.5 EER25651.1 - 0.0087 15.2 0.0 0.026 13.7 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Snurportin1 PF11538.3 EER25651.1 - 0.052 13.3 0.6 0.13 12.0 0.4 1.6 1 0 0 1 1 1 0 Snurportin1 HORMA PF02301.13 EER25652.1 - 1.6e-48 164.9 0.1 1.9e-48 164.7 0.1 1.0 1 0 0 1 1 1 1 HORMA domain FlaG PF03646.10 EER25652.1 - 0.45 10.6 5.0 5.8 7.0 1.2 2.4 2 0 0 2 2 2 0 FlaG protein RNA_pol_Rpb1_5 PF04998.12 EER25653.1 - 5.3e-89 298.1 1.5 9.2e-89 297.3 1.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EER25653.1 - 9.6e-85 284.7 0.0 1.5e-84 284.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EER25653.1 - 2.1e-66 222.9 0.0 4.8e-66 221.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EER25653.1 - 2.5e-35 121.5 0.0 8e-35 119.9 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EER25653.1 - 9.5e-29 99.3 0.1 3.1e-28 97.6 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Glyoxalase_2 PF12681.2 EER25654.1 - 6.4e-06 26.7 0.0 7.3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Opy2 PF09463.5 EER25655.1 - 9.7e-06 25.5 19.5 1.6e-05 24.8 13.5 1.4 1 0 0 1 1 1 1 Opy2 protein 2OG-FeII_Oxy_2 PF13532.1 EER25656.1 - 5.2e-24 85.1 0.0 9.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EER25656.1 - 5e-23 81.9 0.0 1.5e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 Isochorismatase family GST_C_2 PF13410.1 EER25656.1 - 0.018 14.9 0.1 0.043 13.7 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain IlvN PF07991.7 EER25657.1 - 1.2e-46 158.0 0.0 1.8e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EER25657.1 - 2.8e-44 150.5 0.0 4.1e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EER25657.1 - 0.02 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EER25657.1 - 0.094 13.1 0.2 0.39 11.1 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PALP PF00291.20 EER25658.1 - 2.5e-71 240.4 0.4 3.4e-71 239.9 0.3 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rad51 PF08423.6 EER25659.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Rad51 TAF8_C PF10406.4 EER25660.1 - 2.5e-23 81.8 2.0 7.4e-23 80.3 1.4 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EER25660.1 - 4.8e-08 32.6 0.8 2.6e-07 30.2 0.0 2.3 3 0 0 3 3 3 1 Bromodomain associated Competence PF03772.11 EER25661.1 - 0.14 11.1 0.2 0.14 11.1 0.1 1.0 1 0 0 1 1 1 0 Competence protein UQ_con PF00179.21 EER25662.1 - 9.8e-37 125.5 0.0 1.2e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER25662.1 - 0.028 14.1 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Chitin_synth_1 PF01644.12 EER25663.1 - 4.3e-68 228.2 0.0 6.3e-68 227.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EER25663.1 - 3.1e-28 97.2 0.0 5.7e-28 96.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EER25663.1 - 1.3e-24 86.5 0.0 8.9e-20 70.5 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EER25663.1 - 1.1e-11 44.7 0.4 1.1e-11 44.7 0.2 2.8 4 1 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EER25663.1 - 5.4e-07 29.6 0.0 2e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Kringle PF00051.13 EER25664.1 - 0.057 13.5 1.9 0.084 12.9 0.3 2.1 2 0 0 2 2 2 0 Kringle domain zf-CCHC PF00098.18 EER25664.1 - 0.12 12.3 2.0 0.18 11.7 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L18ae PF01775.12 EER25664.1 - 0.67 9.8 8.1 0.45 10.4 2.1 2.4 2 0 0 2 2 2 0 Ribosomal L18ae/LX protein domain PALP PF00291.20 EER25665.1 - 2.7e-59 200.9 0.1 3.1e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GHMP_kinases_C PF08544.8 EER25665.1 - 0.031 14.4 0.0 3.4 7.9 0.0 2.6 2 0 0 2 2 2 0 GHMP kinases C terminal Cpn60_TCP1 PF00118.19 EER25665.1 - 0.074 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family AAA_10 PF12846.2 EER25666.1 - 3.4e-10 39.8 0.1 4.3e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EER25666.1 - 0.0001 21.8 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) DUF87 PF01935.12 EER25666.1 - 0.00067 19.5 0.2 0.53 10.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 EER25666.1 - 0.014 15.5 0.2 5.6 7.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EER25666.1 - 0.016 14.6 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EER25666.1 - 0.03 13.4 0.0 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Gpi16 PF04113.9 EER25666.1 - 0.06 11.3 0.0 0.095 10.7 0.0 1.2 1 0 0 1 1 1 0 Gpi16 subunit, GPI transamidase component SUR7 PF06687.7 EER25667.1 - 5e-31 107.9 7.8 6.4e-31 107.5 5.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family SNARE PF05739.14 EER25668.1 - 3.5e-17 61.8 0.2 3.5e-17 61.8 0.1 2.7 4 0 0 4 4 4 1 SNARE domain Syntaxin PF00804.20 EER25668.1 - 8.6e-16 57.9 0.6 8.6e-16 57.9 0.4 2.9 3 1 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 EER25668.1 - 0.0049 16.4 0.2 0.0049 16.4 0.2 2.4 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin-18_N PF10496.4 EER25668.1 - 0.012 15.4 4.0 0.027 14.2 0.4 2.7 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus NPV_P10 PF05531.7 EER25668.1 - 0.029 14.6 3.8 8.4 6.7 0.1 3.6 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Mu-like_Pro PF10123.4 EER25668.1 - 0.27 10.6 7.7 0.4 10.0 5.3 1.2 1 0 0 1 1 1 0 Mu-like prophage I protein zf-C4H2 PF10146.4 EER25668.1 - 0.28 11.1 3.9 2.8 7.9 0.1 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein AAA_13 PF13166.1 EER25668.1 - 0.32 9.3 9.6 0.17 10.3 4.3 1.8 2 0 0 2 2 2 0 AAA domain MerR-DNA-bind PF09278.6 EER25668.1 - 0.75 10.2 8.9 5.3 7.5 0.1 4.2 3 1 1 4 4 4 0 MerR, DNA binding HNH_2 PF13391.1 EER25669.1 - 8.9e-17 60.6 0.0 2.7e-16 59.0 0.0 1.9 2 0 0 2 2 2 1 HNH endonuclease TLC PF03219.9 EER25671.1 - 0.076 11.4 2.0 0.075 11.5 1.4 1.0 1 0 0 1 1 1 0 TLC ATP/ADP transporter CAAD PF14159.1 EER25671.1 - 0.084 12.5 0.0 0.092 12.4 0.0 1.1 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3551 PF12071.3 EER25671.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) DcuC PF03606.10 EER25671.1 - 0.15 10.2 0.9 0.15 10.2 0.6 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Protocadherin PF08374.6 EER25671.1 - 0.21 11.1 4.6 0.21 11.2 3.2 1.1 1 0 0 1 1 1 0 Protocadherin Lentivirus_VIF PF05851.6 EER25671.1 - 0.32 9.6 2.4 0.31 9.6 1.7 1.0 1 0 0 1 1 1 0 Lentivirus virion infectivity factor (VIF) BLVR PF06375.6 EER25671.1 - 0.37 10.6 10.5 0.33 10.7 7.3 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 EER25671.1 - 1.4 8.7 5.6 1.3 8.8 3.9 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TSGP1 PF07771.6 EER25671.1 - 3.9 7.3 8.4 3.9 7.3 5.8 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 Pkinase PF00069.20 EER25672.1 - 6.7e-27 94.2 0.0 9.6e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25672.1 - 5.3e-10 38.8 0.0 9.5e-09 34.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase RNase_H PF00075.19 EER25674.1 - 1.1e-17 64.5 0.1 1.5e-17 64.1 0.1 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EER25674.1 - 7.2e-05 22.4 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 Reverse transcriptase-like End3 PF12761.2 EER25678.1 - 0.094 12.3 1.0 0.1 12.2 0.7 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Caudo_TAP PF02413.12 EER25678.1 - 0.54 10.4 3.6 0.82 9.8 2.5 1.4 1 1 0 1 1 1 0 Caudovirales tail fibre assembly protein DUF4414 PF14377.1 EER25679.1 - 0.066 13.1 0.1 0.16 11.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4414) Rep_4 PF05797.6 EER25679.1 - 0.088 11.4 0.0 0.15 10.7 0.0 1.3 1 1 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) RCC1 PF00415.13 EER25681.1 - 2.2e-27 94.9 20.2 3.9e-08 33.3 0.1 7.6 6 2 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EER25681.1 - 4e-15 54.9 32.9 1.4e-06 27.7 2.5 6.3 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat Rad9 PF04139.8 EER25682.1 - 6.1e-61 205.7 1.8 9e-61 205.1 1.2 1.3 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EER25682.1 - 3.6e-05 22.6 1.2 0.0081 14.9 0.3 3.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 APC_CDC26 PF10471.4 EER25683.1 - 5 7.9 14.9 0.39 11.4 2.7 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF972 PF06156.8 EER25683.1 - 9.4 6.6 8.5 5.7 7.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) PPR_2 PF13041.1 EER25684.1 - 1.3e-18 66.6 0.0 3.2e-11 42.9 0.0 3.2 2 1 1 3 3 3 2 PPR repeat family PPR_3 PF13812.1 EER25684.1 - 0.00025 21.0 0.0 0.54 10.6 0.0 4.6 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR PF01535.15 EER25684.1 - 0.00045 20.0 0.7 0.026 14.4 0.0 3.3 4 0 0 4 4 4 1 PPR repeat DEAD PF00270.24 EER25685.1 - 1.9e-45 154.4 0.0 6.1e-44 149.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER25685.1 - 5.4e-28 96.6 0.0 1.2e-27 95.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25685.1 - 0.0002 21.2 0.0 0.00057 19.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EER25685.1 - 0.003 17.5 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 EER25685.1 - 0.023 13.1 0.0 0.61 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) DUF2443 PF10398.4 EER25685.1 - 0.042 13.6 0.4 0.094 12.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) AAA_19 PF13245.1 EER25685.1 - 0.088 12.5 0.4 5 6.9 0.2 2.9 3 1 0 3 3 3 0 Part of AAA domain Phos_pyr_kin PF08543.7 EER25687.1 - 6.1e-81 271.2 0.6 8.2e-81 270.8 0.4 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EER25687.1 - 7.7e-47 159.7 0.4 3.5e-23 82.4 0.1 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.19 EER25687.1 - 0.00017 20.8 0.1 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 EER25687.1 - 0.0013 17.9 1.1 0.058 12.5 0.1 2.3 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family MRF_C1 PF13887.1 EER25687.1 - 0.11 11.5 0.3 0.22 10.5 0.2 1.4 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 DNA_pol_B PF00136.16 EER25688.1 - 6.3e-115 384.6 4.8 1.1e-114 383.8 3.3 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EER25688.1 - 1.5e-66 223.3 0.6 3.1e-66 222.3 0.4 1.6 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EER25688.1 - 3.9e-41 140.9 0.0 5.9e-40 137.0 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EER25688.1 - 2.2e-26 91.4 10.5 8.4e-26 89.5 7.3 2.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Ribosomal_L30_N PF08079.7 EER25689.1 - 3.7e-26 90.9 13.3 7.6e-26 89.9 9.2 1.5 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EER25689.1 - 3.2e-18 65.0 1.8 8.4e-18 63.7 1.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e EAP30 PF04157.11 EER25690.1 - 3.2e-59 199.7 0.0 6e-59 198.9 0.0 1.4 1 1 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 EER25690.1 - 0.0012 18.4 0.0 0.0049 16.5 0.0 2.0 1 0 0 1 1 1 1 MarR family eIF-3c_N PF05470.7 EER25691.1 - 3e-173 577.1 25.8 5.1e-137 457.4 1.7 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EER25691.1 - 5.6e-13 49.1 3.6 1.1e-11 45.0 0.2 3.6 2 1 0 2 2 2 1 PCI domain DUF4629 PF15442.1 EER25691.1 - 6 6.9 11.0 0.28 11.2 3.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) Pkinase PF00069.20 EER25692.1 - 1.8e-52 178.0 0.0 6.8e-52 176.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25692.1 - 1.4e-23 83.3 0.0 2.8e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER25692.1 - 0.00035 20.3 1.1 0.00056 19.7 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EER25692.1 - 0.0023 17.2 0.2 0.0072 15.6 0.2 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EER25692.1 - 0.097 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) SNF2_N PF00176.18 EER25693.1 - 1.5e-70 237.3 0.0 3.4e-70 236.2 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER25693.1 - 1.2e-13 50.7 0.0 3e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25693.1 - 1.3e-05 25.1 0.1 0.012 15.4 0.0 3.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Mucin PF01456.12 EER25694.1 - 2.2 8.0 16.2 0.068 12.9 6.7 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Med27 PF11571.3 EER25695.1 - 2.4e-16 59.6 0.0 4.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 Bclt PF15318.1 EER25695.1 - 0.11 12.5 1.0 0.19 11.7 0.7 1.4 1 0 0 1 1 1 0 Putative Bcl-2 like protein of testis ArsB PF02040.10 EER25696.1 - 7.3e-16 58.1 18.5 8e-10 38.2 5.2 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein DUF3708 PF12501.3 EER25696.1 - 0.014 15.2 0.1 0.83 9.4 0.0 2.8 3 0 0 3 3 3 0 Phosphate ATP-binding cassette transporter Usp PF00582.21 EER25697.1 - 1.2e-18 67.6 0.0 2.3e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Universal stress protein family BSP_II PF05432.6 EER25698.1 - 0.019 14.2 9.1 0.03 13.6 6.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIF_alpha PF05793.7 EER25698.1 - 4.5 5.5 10.4 5.8 5.1 7.2 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.20 EER25699.1 - 9.9e-62 208.4 0.0 1.7e-61 207.6 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25699.1 - 6.8e-27 94.1 0.0 1.1e-26 93.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER25699.1 - 0.009 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EER25699.1 - 0.0094 15.0 0.1 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER25699.1 - 0.039 13.6 0.1 0.039 13.6 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sod_Cu PF00080.15 EER25700.1 - 4.9e-13 49.4 0.0 6.9e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EER25700.1 - 1.8e-12 47.2 0.0 3.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Heavy-metal-associated domain Chordopox_RPO7 PF05864.7 EER25700.1 - 0.046 13.8 0.2 10 6.3 0.0 2.4 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) TPR_1 PF00515.23 EER25701.1 - 1.9e-14 52.5 5.1 1.2e-06 27.9 0.1 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EER25701.1 - 3.6e-14 51.4 4.4 6e-05 22.6 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EER25701.1 - 2e-12 46.5 1.5 4.8e-09 35.7 0.1 3.3 2 1 1 3 3 3 2 TPR repeat TPR_12 PF13424.1 EER25701.1 - 4.3e-09 36.1 0.4 5.7e-06 26.1 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.19 EER25701.1 - 6e-07 29.0 0.0 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.1 EER25701.1 - 4e-06 26.2 2.9 0.0079 15.9 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EER25701.1 - 4.4e-06 26.0 0.3 5.6e-05 22.6 0.0 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EER25701.1 - 9.9e-05 22.5 0.1 2.6 8.6 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EER25701.1 - 0.00023 21.7 0.7 0.0094 16.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EER25701.1 - 0.00067 19.6 2.6 0.04 14.1 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EER25701.1 - 0.0038 17.7 0.0 0.13 12.9 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EER25701.1 - 0.17 12.0 1.2 1.1 9.4 0.1 2.4 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Syntaxin-18_N PF10496.4 EER25702.1 - 9.2e-17 60.6 0.0 9.2e-17 60.6 0.0 3.0 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EER25702.1 - 2.6e-05 23.8 2.4 7.7e-05 22.3 0.7 2.6 3 0 0 3 3 3 1 SNARE domain Rab5-bind PF09311.6 EER25702.1 - 0.0015 18.4 1.0 0.0015 18.4 0.7 2.6 3 0 0 3 3 3 1 Rabaptin-like protein BLOC1_2 PF10046.4 EER25702.1 - 0.029 14.4 5.1 0.59 10.2 2.0 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nexin_C PF08628.7 EER25702.1 - 7.6 6.6 7.2 1.1 9.3 0.0 3.0 3 1 1 4 4 4 0 Sorting nexin C terminal Acyl_transf_3 PF01757.17 EER25703.1 - 1.3e-10 40.6 29.3 1.5e-10 40.4 19.9 1.3 1 1 0 1 1 1 1 Acyltransferase family Aminotran_1_2 PF00155.16 EER25704.1 - 1.6e-84 283.9 0.0 1.9e-84 283.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-RING_2 PF13639.1 EER25705.1 - 2.8e-15 55.8 4.4 4.9e-15 55.0 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EER25705.1 - 5.5e-08 32.3 3.0 8.8e-08 31.6 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER25705.1 - 4e-07 29.9 4.5 6.8e-07 29.2 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EER25705.1 - 5.3e-07 29.6 0.8 9.6e-07 28.8 0.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EER25705.1 - 2e-06 27.4 1.9 4.2e-06 26.3 1.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EER25705.1 - 5.4e-05 22.7 1.6 9.3e-05 22.0 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EER25705.1 - 0.0022 17.8 3.0 0.0041 16.9 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EER25705.1 - 0.0037 16.8 3.6 0.0066 16.0 2.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EER25705.1 - 0.068 13.0 5.5 0.13 12.2 3.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Metal_resist PF13801.1 EER25705.1 - 0.17 11.9 5.1 1.4 8.9 0.9 2.4 2 0 0 2 2 2 0 Heavy-metal resistance PHD PF00628.24 EER25705.1 - 0.54 10.0 2.8 1.2 8.8 1.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EER25705.1 - 1.4 8.9 3.3 2.4 8.2 2.3 1.4 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.3 EER25705.1 - 8.6 6.4 7.3 25 4.9 3.2 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain MS_channel PF00924.13 EER25706.1 - 2.2e-17 63.0 2.5 4.8e-17 61.9 1.8 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EER25706.1 - 0.00076 18.6 0.2 0.0017 17.5 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EER25706.1 - 0.0058 16.7 0.2 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EER25706.1 - 0.028 14.3 0.0 0.073 12.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain FA_desaturase PF00487.19 EER25706.1 - 0.44 9.9 4.5 2.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Fatty acid desaturase NRDE PF05742.7 EER25707.1 - 8.1e-46 156.5 0.0 1.6e-45 155.5 0.0 1.5 1 1 0 1 1 1 1 NRDE protein BPL_N PF09825.4 EER25708.1 - 6.9e-141 469.2 0.0 8.7e-141 468.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EER25708.1 - 2.4e-20 72.8 0.0 4.9e-20 71.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family CHCH PF06747.8 EER25709.1 - 2.6e-05 24.0 5.6 3.4e-05 23.6 3.9 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EER25709.1 - 0.0088 15.7 1.8 0.011 15.4 1.2 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EER25709.1 - 0.022 14.7 0.5 0.027 14.5 0.4 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Toxin_25 PF08095.6 EER25709.1 - 0.067 12.9 0.4 0.067 12.9 0.2 2.2 2 1 0 2 2 2 0 Hefutoxin family Mgm101p PF06420.7 EER25710.1 - 1.9e-91 304.0 0.0 2.4e-91 303.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MFS_1 PF07690.11 EER25711.1 - 3.8e-13 48.8 49.9 8.5e-09 34.5 9.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER25711.1 - 0.00022 19.9 10.4 0.00022 19.9 7.2 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter TB2_DP1_HVA22 PF03134.14 EER25712.1 - 1.5e-14 53.4 5.9 2.5e-14 52.7 4.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MIF4G PF02854.14 EER25713.1 - 1e-48 165.5 0.0 1.7e-48 164.8 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EER25713.1 - 2.8e-22 78.4 2.8 8.8e-22 76.7 1.9 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 RRM_1 PF00076.17 EER25715.1 - 0.00065 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2263 PF10021.4 EER25716.1 - 2.9e-18 66.2 0.0 5.9e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 EER25716.1 - 0.095 12.6 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Macro domain Methyltransf_28 PF02636.12 EER25717.1 - 2.3e-81 272.9 0.0 2.9e-81 272.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.15 EER25718.1 - 1.7e-14 54.0 0.0 2.1e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.15 EER25719.1 - 7.4e-06 25.3 4.9 1.6e-05 24.2 3.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 Mucin PF01456.12 EER25719.1 - 0.069 12.9 5.2 0.12 12.1 3.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PGI PF00342.14 EER25721.1 - 1.7e-221 735.8 0.6 1.9e-221 735.6 0.4 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase WSC PF01822.14 EER25723.1 - 1.1e-39 134.2 32.1 1.8e-20 72.6 8.8 2.5 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 EER25723.1 - 9.4e-24 84.1 0.1 2e-23 83.1 0.1 1.5 1 0 0 1 1 1 1 Peroxidase PSI_PSAK PF01241.13 EER25723.1 - 0.0092 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Photosystem I psaG / psaK Glyco_trans_2_3 PF13632.1 EER25724.1 - 6.8e-50 169.4 1.3 6.8e-50 169.4 0.9 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EER25724.1 - 0.00011 22.0 0.0 0.00051 19.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EER25724.1 - 0.053 13.2 0.0 0.5 10.0 0.0 2.4 3 0 0 3 3 3 0 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.16 EER25726.1 - 5.1e-22 78.0 0.3 4e-21 75.1 0.1 2.0 1 1 0 2 2 2 1 Glycosyl hydrolases family 16 Bac_Ubq_Cox PF01654.12 EER25726.1 - 0.19 10.1 0.0 0.28 9.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial Cytochrome Ubiquinol Oxidase WSC PF01822.14 EER25727.1 - 5.9e-51 170.3 41.7 3.4e-20 71.7 7.3 3.4 3 0 0 3 3 3 3 WSC domain Glyoxal_oxid_N PF07250.6 EER25727.1 - 2.5e-29 102.0 0.0 8.7e-28 97.0 0.0 2.8 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EER25727.1 - 8.1e-23 80.3 0.0 1.8e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PWI PF01480.12 EER25729.1 - 6.3e-12 45.4 0.3 2e-11 43.8 0.2 1.9 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.17 EER25729.1 - 0.00073 19.1 0.0 0.002 17.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAD_binding_1 PF00667.15 EER25729.1 - 0.04 13.3 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_4 PF01565.18 EER25730.1 - 9.1e-23 80.2 3.2 1.5e-22 79.5 2.2 1.4 1 0 0 1 1 1 1 FAD binding domain Fungal_trans_2 PF11951.3 EER25731.1 - 0.0061 15.1 0.4 0.0087 14.7 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2713 PF10897.3 EER25731.1 - 0.095 11.9 0.3 0.3 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2713) DUF2310 PF10071.4 EER25731.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) TIM21 PF08294.6 EER25732.1 - 3e-40 137.2 0.0 3.8e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EER25732.1 - 1.9e-08 33.8 0.0 3.6e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.13 EER25733.1 - 4e-35 120.1 0.2 6.4e-35 119.4 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Pterin_bind PF00809.17 EER25734.1 - 2.1e-62 210.2 0.0 4.9e-62 209.0 0.0 1.6 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.15 EER25734.1 - 8.7e-41 138.6 0.0 1.7e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 EER25735.1 - 3e-71 240.2 0.9 3.6e-71 240.0 0.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EER25735.1 - 2.8e-09 36.3 0.4 4.8e-09 35.5 0.2 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EER25735.1 - 5.1e-07 28.8 2.0 8.4e-07 28.1 1.4 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 EER25735.1 - 8.8e-05 21.5 0.3 0.00014 20.9 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 EER25735.1 - 0.0009 18.2 0.7 0.0017 17.3 0.5 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NanE PF04131.9 EER25735.1 - 0.077 11.9 0.3 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase eIF3g PF12353.3 EER25736.1 - 2.4e-47 160.0 1.2 3.5e-47 159.4 0.9 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EER25736.1 - 3e-15 55.6 0.0 4.8e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER25736.1 - 1.1e-12 47.7 0.1 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25736.1 - 1.2e-06 28.2 0.1 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDT80_PhoG PF05224.7 EER25737.1 - 2.9e-40 138.2 0.0 4.2e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family APH PF01636.18 EER25740.1 - 3.8e-09 36.6 1.2 4.3e-08 33.1 0.0 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family AMP-binding PF00501.23 EER25741.1 - 1.2e-80 270.9 0.0 1.8e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER25741.1 - 0.06 14.2 0.0 0.14 13.1 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain RNB PF00773.14 EER25742.1 - 2.7e-50 171.4 0.0 4.2e-49 167.5 0.0 2.2 1 1 0 1 1 1 1 RNB domain adh_short PF00106.20 EER25743.1 - 7.4e-17 61.7 0.0 1.1e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER25743.1 - 6.3e-07 29.4 0.0 8.8e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF294 PF03445.8 EER25743.1 - 0.0069 16.0 0.2 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Putative nucleotidyltransferase DUF294 KR PF08659.5 EER25743.1 - 0.0076 15.9 0.0 0.014 15.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EER25743.1 - 0.028 14.2 1.5 0.85 9.4 0.1 2.7 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EER25743.1 - 0.066 12.3 0.0 0.53 9.4 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EER25743.1 - 0.16 10.8 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TcdB_toxin_midC PF12255.3 EER25744.1 - 0.099 12.2 0.0 0.13 11.8 0.0 1.3 1 1 0 1 1 1 0 Insecticide toxin TcdB middle/C-terminal region CTNNBL PF08216.6 EER25745.1 - 2.8e-36 123.3 0.5 1.8e-35 120.7 0.0 2.6 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EER25745.1 - 0.0061 16.3 0.1 2.6 8.0 0.0 3.7 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Mo25 PF08569.6 EER25745.1 - 0.023 13.7 0.5 0.075 12.0 0.3 1.9 1 1 1 2 2 2 0 Mo25-like DUF4020 PF13212.1 EER25745.1 - 0.044 13.3 0.2 0.23 11.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) HEAT_2 PF13646.1 EER25745.1 - 0.1 12.8 4.5 1.2 9.4 0.2 3.5 2 1 2 4 4 4 0 HEAT repeats RNA_pol_Rpb2_6 PF00562.23 EER25746.1 - 8.7e-124 413.1 0.1 1.6e-123 412.2 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EER25746.1 - 4.7e-61 205.2 0.0 7.2e-61 204.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EER25746.1 - 1.6e-47 161.3 0.0 2.8e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EER25746.1 - 6.5e-31 106.4 0.0 1.3e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EER25746.1 - 1.7e-24 85.3 0.3 3.8e-24 84.2 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 EER25746.1 - 1.1e-23 82.8 0.3 2.7e-23 81.6 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EER25746.1 - 1.9e-23 81.9 0.1 4.9e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 zf-CGNR PF11706.3 EER25747.1 - 0.41 10.2 4.5 0.82 9.2 1.2 2.3 2 0 0 2 2 2 0 CGNR zinc finger ADH_N PF08240.7 EER25748.1 - 7.7e-23 80.3 0.9 1.2e-22 79.7 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER25748.1 - 6.9e-18 64.4 0.0 1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EER25748.1 - 0.0033 16.5 0.1 0.0053 15.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4241 PF14025.1 EER25748.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Nucleopor_Nup85 PF07575.8 EER25750.1 - 3.8e-17 61.7 0.0 2e-15 56.0 0.0 2.9 1 1 0 1 1 1 1 Nup85 Nucleoporin ADIP PF11559.3 EER25751.1 - 4.2e-38 130.6 9.5 4.2e-38 130.6 6.6 1.7 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding Use1 PF09753.4 EER25751.1 - 6.3e-05 22.5 4.2 9.5e-05 21.9 2.9 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 BicD PF09730.4 EER25751.1 - 0.00047 18.6 5.6 0.0053 15.1 3.9 1.9 2 0 0 2 2 2 1 Microtubule-associated protein Bicaudal-D FUSC PF04632.7 EER25751.1 - 0.045 12.2 2.1 0.057 11.8 1.1 1.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family Spc7 PF08317.6 EER25751.1 - 0.047 12.3 9.5 0.09 11.4 6.6 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC74_C PF14917.1 EER25751.1 - 0.15 12.1 4.7 0.28 11.2 1.2 2.2 1 1 1 2 2 2 0 Coiled coil protein 74, C terminal AKNA PF12443.3 EER25751.1 - 0.28 11.2 4.6 2 8.4 0.9 3.0 2 1 1 3 3 3 0 AT-hook-containing transcription factor DUF3349 PF11829.3 EER25751.1 - 0.37 11.2 2.5 1.9 8.9 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) Sec2p PF06428.6 EER25751.1 - 0.43 10.4 8.3 0.46 10.3 2.2 2.8 2 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p DUF641 PF04859.7 EER25751.1 - 0.78 9.4 12.1 0.41 10.4 3.1 3.0 2 2 1 3 3 3 0 Plant protein of unknown function (DUF641) APG6 PF04111.7 EER25751.1 - 0.98 8.3 11.1 0.07 12.1 4.3 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Bacillus_HBL PF05791.6 EER25751.1 - 3.4 6.9 9.4 0.62 9.3 3.4 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF3552 PF12072.3 EER25751.1 - 4 6.6 16.6 1.1 8.4 3.9 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) Atg14 PF10186.4 EER25751.1 - 4.7 6.0 12.0 8.5 5.2 8.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 F-box PF00646.28 EER25752.1 - 0.00055 19.5 0.2 0.0032 17.0 0.1 2.4 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.1 EER25752.1 - 0.00099 18.9 7.2 1 9.6 0.0 6.8 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.2 EER25752.1 - 0.0053 16.3 18.2 0.022 14.3 0.6 6.8 5 3 2 7 7 7 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EER25752.1 - 0.0061 16.5 5.1 20 5.9 0.0 6.8 8 0 0 8 8 8 1 Leucine rich repeat LRR_8 PF13855.1 EER25752.1 - 0.14 11.9 12.5 0.16 11.7 0.1 5.4 6 2 1 7 7 7 0 Leucine rich repeat LRR_2 PF07723.8 EER25752.1 - 2.4 8.7 5.3 13 6.4 0.2 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat IDO PF01231.13 EER25753.1 - 8.3e-41 139.8 0.0 1.3e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CLTH PF10607.4 EER25754.1 - 5.6e-37 126.6 0.0 9.9e-37 125.8 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EER25754.1 - 4.8e-22 78.3 0.6 8.5e-22 77.5 0.4 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EER25754.1 - 0.00052 19.6 0.5 0.0013 18.3 0.0 2.0 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.6 EER25755.1 - 3.8e-59 200.3 29.2 4.5e-59 200.0 20.3 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 GDPD PF03009.12 EER25756.1 - 1.6e-46 158.8 0.0 2.4e-46 158.3 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EER25756.1 - 8.8e-27 93.2 1.4 2.4e-09 37.4 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EER25756.1 - 1.6e-19 68.6 12.3 3.6e-07 29.6 0.0 6.7 6 1 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EER25756.1 - 3.9e-16 59.0 4.4 6.1e-07 29.7 0.1 4.2 3 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER25756.1 - 4.7e-16 58.4 1.5 1.7e-05 24.8 0.0 5.0 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER25756.1 - 5e-14 51.0 5.8 0.0032 17.5 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat SPX PF03105.14 EER25756.1 - 4.9e-08 33.0 0.0 0.00035 20.4 0.0 2.2 2 0 0 2 2 2 2 SPX domain Ank PF00023.25 EER25757.1 - 6.5e-32 107.7 0.5 3.4e-07 29.7 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 EER25757.1 - 1.5e-31 108.5 0.0 4.4e-12 46.1 0.0 4.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER25757.1 - 3.5e-21 75.1 0.3 3e-05 24.3 0.0 5.6 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER25757.1 - 3.9e-20 71.4 0.6 2.8e-06 27.3 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER25757.1 - 9.9e-17 59.3 0.1 0.0015 18.5 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Methyltransf_31 PF13847.1 EER25758.1 - 2e-30 105.4 0.0 2.9e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER25758.1 - 6.1e-18 65.1 0.1 1.3e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER25758.1 - 6.9e-16 58.0 0.1 1.2e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EER25758.1 - 3.3e-14 53.4 0.1 5.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER25758.1 - 5.1e-14 52.4 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER25758.1 - 1.4e-13 50.8 0.0 2.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EER25758.1 - 1.8e-10 40.6 0.0 2.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EER25758.1 - 2.8e-10 40.2 0.0 5.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER25758.1 - 5.1e-10 39.7 0.0 9.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EER25758.1 - 9.5e-10 38.0 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EER25758.1 - 2e-07 30.5 0.0 2.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EER25758.1 - 5.5e-07 28.9 0.0 9.3e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EER25758.1 - 8e-06 25.5 0.1 2.9e-05 23.7 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 EER25758.1 - 0.00011 21.8 0.1 0.00024 20.7 0.1 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.8 EER25758.1 - 0.0009 18.6 1.3 0.003 16.9 0.2 2.1 2 1 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_3 PF01596.12 EER25758.1 - 0.0034 16.4 0.2 0.013 14.5 0.1 1.9 2 1 0 2 2 2 1 O-methyltransferase GidB PF02527.10 EER25758.1 - 0.0068 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_24 PF13578.1 EER25758.1 - 0.027 15.2 0.0 0.073 13.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EER25758.1 - 0.043 13.8 0.0 0.078 12.9 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.5 EER25758.1 - 0.049 13.1 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CheR PF01739.13 EER25758.1 - 0.079 12.2 0.0 2.2 7.5 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain ADH_zinc_N PF00107.21 EER25758.1 - 0.094 12.2 0.1 0.45 10.0 0.1 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Chromo_shadow PF01393.14 EER25758.1 - 0.1 12.4 0.3 9.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Chromo shadow domain DnaJ PF00226.26 EER25759.1 - 3.1e-14 52.4 0.0 8.7e-14 51.0 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain SHS2_Rpb7-N PF03876.12 EER25760.1 - 0.0073 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Pyr_redox_2 PF07992.9 EER25761.1 - 7.1e-31 107.6 0.1 1.2e-30 106.9 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER25761.1 - 4.5e-17 62.2 0.2 1.4e-14 54.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EER25761.1 - 9.5e-14 50.7 0.0 2.1e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EER25761.1 - 4.3e-11 43.2 0.0 0.0013 18.8 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EER25761.1 - 0.00014 21.4 0.0 0.00043 19.9 0.0 1.9 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.1 EER25761.1 - 0.0005 19.8 0.1 2.3 8.0 0.0 3.2 2 1 1 3 3 3 1 FAD-NAD(P)-binding Reductase_C PF14759.1 EER25761.1 - 0.00056 20.1 0.0 0.0025 18.0 0.0 2.1 2 0 0 2 2 2 1 Reductase C-terminal K_oxygenase PF13434.1 EER25761.1 - 0.0012 17.8 0.0 0.97 8.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EER25761.1 - 0.0019 17.1 0.2 0.54 9.1 0.0 3.3 3 1 1 4 4 4 1 FAD dependent oxidoreductase DUF1188 PF06690.6 EER25761.1 - 0.0047 16.1 0.1 0.0071 15.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) TrkA_N PF02254.13 EER25761.1 - 0.0079 16.1 0.4 2.2 8.3 0.1 2.5 2 0 0 2 2 2 1 TrkA-N domain HI0933_like PF03486.9 EER25761.1 - 0.035 12.5 0.0 5.2 5.4 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 EER25761.1 - 0.056 12.0 0.0 6.9 5.1 0.0 2.5 2 1 1 3 3 3 0 Tryptophan halogenase Arrestin_N PF00339.24 EER25763.1 - 1.7e-12 47.3 0.1 5.9e-07 29.4 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.5 EER25763.1 - 0.0065 15.6 0.2 0.015 14.3 0.0 1.6 2 0 0 2 2 2 1 Rgp1 Bul1_C PF04426.7 EER25763.1 - 0.11 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Bul1 C terminus V-ATPase_G PF03179.10 EER25764.1 - 1.2e-34 118.7 16.4 1.4e-34 118.5 11.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF2251 PF10008.4 EER25764.1 - 0.028 14.5 0.1 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2251) DUF3552 PF12072.3 EER25764.1 - 0.11 11.6 19.7 0.52 9.4 13.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 EER25764.1 - 0.16 11.7 18.9 0.034 13.9 7.8 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF3154 PF11351.3 EER25764.1 - 0.33 10.6 4.7 0.4 10.4 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3154) DUF2215 PF10225.4 EER25764.1 - 0.52 9.7 1.7 0.57 9.5 1.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) CAF-1_p150 PF11600.3 EER25764.1 - 1.3 8.3 19.7 1.6 8.0 13.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4604 PF15377.1 EER25764.1 - 1.5 9.0 14.6 1.9 8.6 10.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) OmpH PF03938.9 EER25764.1 - 1.6 8.6 12.8 2 8.3 8.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HrpE PF06188.7 EER25764.1 - 2 8.1 9.6 55 3.4 6.4 2.0 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Colicin-DNase PF12639.2 EER25764.1 - 2.7 8.2 5.8 4.1 7.6 4.0 1.4 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin AIF-MLS PF14962.1 EER25764.1 - 2.8 7.5 7.8 3.2 7.3 5.4 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DivIVA PF05103.8 EER25764.1 - 4.4 7.3 15.2 36 4.4 10.5 2.0 1 1 0 1 1 1 0 DivIVA protein KfrA_N PF11740.3 EER25764.1 - 5.6 7.4 11.8 0.53 10.7 4.1 2.1 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term CCDC66 PF15236.1 EER25764.1 - 9.1 5.8 20.5 17 4.9 14.3 1.4 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 66 DUF948 PF06103.6 EER25766.1 - 0.37 10.6 10.1 0.51 10.2 1.3 3.7 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF869 PF05911.6 EER25766.1 - 1.5 6.9 25.2 0.18 10.0 13.0 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF972 PF06156.8 EER25766.1 - 8.5 6.7 19.0 3.2 8.1 1.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Striatin PF08232.7 EER25766.1 - 8.9 6.6 21.2 3.3 8.0 1.1 3.0 1 1 1 2 2 2 0 Striatin family DivIVA PF05103.8 EER25766.1 - 9.1 6.3 28.9 4.8 7.2 0.2 4.3 3 1 1 4 4 4 0 DivIVA protein Methyltransf_16 PF10294.4 EER25767.1 - 7.6e-14 51.5 0.0 1.2e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EER25767.1 - 1.3e-06 28.9 0.0 2.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER25767.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EER25767.1 - 0.0012 19.2 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER25767.1 - 0.012 15.3 0.0 0.049 13.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EER25767.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EER25767.1 - 0.016 15.6 0.0 0.053 14.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EER25767.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EER25767.1 - 0.074 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EER25767.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 EER25768.1 - 2.5e-34 116.9 0.0 3.7e-34 116.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e Pro_isomerase PF00160.16 EER25769.1 - 5.7e-38 130.5 0.0 8.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EER25769.1 - 5.6e-16 57.9 0.0 1.1e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER25769.1 - 4.4e-12 45.8 0.0 9.1e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25769.1 - 1.5e-09 37.5 0.1 3.7e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER25769.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif UDPGP PF01704.13 EER25770.1 - 2.1e-57 194.5 0.0 2.9e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EER25770.1 - 0.0071 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fer4_20 PF14691.1 EER25770.1 - 0.068 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster zf-CCHC PF00098.18 EER25771.1 - 2.9e-39 131.1 58.7 2.3e-07 30.3 0.6 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EER25771.1 - 3.3e-08 33.0 43.2 0.067 12.8 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EER25771.1 - 3.7e-05 23.3 43.7 0.023 14.4 0.5 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 EER25771.1 - 0.066 12.7 0.3 0.066 12.7 0.2 7.1 4 2 3 7 7 7 0 Zinc knuckle Rad51 PF08423.6 EER25772.1 - 8.3e-111 368.9 0.0 1.2e-110 368.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EER25772.1 - 5.8e-08 32.3 0.0 8.2e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EER25772.1 - 1.1e-05 24.6 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EER25772.1 - 0.045 13.9 0.2 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain RRP7 PF12923.2 EER25773.1 - 8.2e-31 106.7 9.7 8.2e-31 106.7 6.7 1.7 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EER25775.1 - 5.8e-46 154.0 0.0 7.9e-17 60.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER25775.1 - 7.1e-28 96.3 0.0 1.9e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25775.1 - 2.9e-21 75.0 0.0 2.6e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EER25775.1 - 1.3e-05 24.9 0.0 9.8e-05 22.1 0.0 2.2 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EER25775.1 - 0.00018 21.1 0.1 0.0085 15.8 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif MCR_alpha_N PF02745.10 EER25778.1 - 0.22 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain LisH PF08513.6 EER25779.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 LisH TRAPP PF04051.11 EER25780.1 - 1.3e-33 115.6 0.0 3.4e-33 114.3 0.0 1.6 1 1 1 2 2 2 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EER25781.1 - 1e-54 180.5 14.5 1.3e-08 34.4 0.5 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EER25781.1 - 0.0012 17.6 3.9 0.25 10.0 0.5 3.0 2 1 0 3 3 3 2 Nup133 N terminal like Glyco_hydro_47 PF01532.15 EER25783.1 - 1.6e-130 435.8 0.0 2.1e-130 435.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PAN_1 PF00024.21 EER25784.1 - 6.3e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.11 EER25784.1 - 0.0041 16.3 1.3 0.0093 15.2 0.1 2.1 2 1 0 2 2 2 1 Fringe-like Pribosyltran PF00156.22 EER25785.1 - 2.8e-17 62.5 0.0 3.7e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EER25785.1 - 0.014 14.6 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Cu-oxidase_3 PF07732.10 EER25787.1 - 1.8e-09 37.3 0.1 1.4e-07 31.2 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EER25787.1 - 2.6e-08 33.4 0.0 0.0094 15.4 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EER25787.1 - 0.0032 17.3 0.0 0.5 10.2 0.0 2.4 2 0 0 2 2 2 2 Cupredoxin-like domain Ribonuc_L-PSP PF01042.16 EER25789.1 - 2e-41 140.5 0.1 2.2e-41 140.3 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP BID PF06393.6 EER25789.1 - 0.0091 15.3 0.0 0.0091 15.3 0.0 1.1 1 0 0 1 1 1 1 BH3 interacting domain (BID) Membr_traf_MHD PF10540.4 EER25790.1 - 3.1e-26 91.7 0.1 2.9e-25 88.6 0.0 2.6 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EER25790.1 - 2e-14 53.1 0.0 4.2e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain NDUF_B8 PF05821.6 EER25791.1 - 9.2e-08 31.9 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) SNF2_N PF00176.18 EER25792.1 - 1.9e-73 246.8 1.6 3.9e-73 245.8 1.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER25792.1 - 8.4e-15 54.4 0.0 2.6e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25792.1 - 5.8e-07 29.5 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EER25792.1 - 2.4e-06 27.1 0.0 1e-05 25.1 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSA PF07529.8 EER25792.1 - 0.0005 19.8 11.8 0.00064 19.4 6.7 2.4 2 0 0 2 2 2 1 HSA Exonuc_VII_L PF02601.10 EER25792.1 - 0.37 9.9 5.4 0.78 8.8 3.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Clr5 PF14420.1 EER25793.1 - 1.1e-13 50.8 0.7 1.1e-13 50.8 0.5 1.7 2 0 0 2 2 2 1 Clr5 domain GlutR_dimer PF00745.15 EER25793.1 - 0.15 12.0 0.2 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain ADH_zinc_N PF00107.21 EER25794.1 - 1.8e-30 105.1 0.5 3.1e-30 104.3 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER25794.1 - 1.3e-07 31.3 0.0 7.2e-07 28.9 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EER25794.1 - 1.7e-07 32.1 0.0 3.8e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pep_deformylase PF01327.16 EER25794.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase GRP PF07172.6 EER25795.1 - 0.01 16.2 28.1 0.01 16.2 19.5 2.4 1 1 1 2 2 2 0 Glycine rich protein family zf-Mss51 PF13824.1 EER25796.1 - 2.5e-28 97.6 10.0 1e-27 95.7 5.6 2.4 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 Elf1 PF05129.8 EER25796.1 - 0.043 13.5 2.5 3.3 7.4 0.3 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-MYND PF01753.13 EER25796.1 - 0.12 12.2 5.8 0.057 13.3 1.5 2.1 2 0 0 2 2 2 0 MYND finger Oxysterol_BP PF01237.13 EER25797.1 - 2.3e-132 440.8 0.2 8.4e-132 438.9 0.0 2.0 3 0 0 3 3 3 1 Oxysterol-binding protein Ank_5 PF13857.1 EER25797.1 - 4e-20 71.3 1.1 4.4e-14 52.1 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EER25797.1 - 7.9e-18 64.5 0.0 8.6e-13 48.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EER25797.1 - 4.2e-17 61.0 0.6 7e-07 28.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EER25797.1 - 1.4e-15 55.8 0.0 4.7e-06 26.3 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EER25797.1 - 5.6e-12 45.8 0.0 7.4e-09 35.8 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 EER25797.1 - 6.9e-11 42.2 0.1 1.6e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EER25797.1 - 1.2e-06 28.4 1.2 2.9e-06 27.2 0.3 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain LLC1 PF14945.1 EER25797.1 - 0.0035 17.6 1.1 0.0035 17.6 0.7 2.6 3 0 0 3 3 3 1 Normal lung function maintenance, Low in Lung Cancer 1 protein DUF2384 PF09722.5 EER25797.1 - 0.096 12.5 0.1 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2384) ATP12 PF07542.6 EER25798.1 - 7.7e-34 116.2 0.1 1.2e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_tranf_2_3 PF13641.1 EER25799.1 - 5.8e-25 88.4 0.1 8.1e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EER25799.1 - 1.7e-08 34.2 0.0 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EER25799.1 - 8e-07 28.5 0.1 1.3e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 21 Pyr_redox_3 PF13738.1 EER25801.1 - 1.1e-19 71.3 0.0 1.1e-18 68.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER25801.1 - 1.2e-18 66.6 0.0 2.7e-17 62.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EER25801.1 - 6e-12 45.1 0.1 4.8e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EER25801.1 - 8.3e-11 42.1 0.0 1.3e-10 41.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER25801.1 - 2.7e-06 26.6 2.0 0.00011 21.4 0.1 2.6 3 0 0 3 3 3 1 Thi4 family NAD_binding_8 PF13450.1 EER25801.1 - 2.9e-06 27.1 1.8 1.8e-05 24.6 0.1 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EER25801.1 - 0.00022 21.0 1.7 0.041 13.6 0.9 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EER25801.1 - 0.0017 17.3 6.9 0.0061 15.4 0.6 3.0 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EER25801.1 - 0.0064 15.6 3.9 0.82 8.6 0.2 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EER25801.1 - 0.025 14.9 0.5 3.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EER25801.1 - 0.097 11.5 0.1 0.23 10.3 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein HI0933_like PF03486.9 EER25801.1 - 0.13 10.7 2.5 2.7 6.3 0.3 3.1 3 0 0 3 3 3 0 HI0933-like protein GIDA PF01134.17 EER25801.1 - 0.61 8.8 4.5 0.9 8.3 0.3 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EER25801.1 - 1.1 8.0 6.2 0.3 9.9 0.4 2.5 3 0 0 3 3 3 0 FAD binding domain DDE_1 PF03184.14 EER25802.1 - 2.6e-15 56.1 2.6 3.9e-15 55.6 1.8 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease AraC_binding PF02311.14 EER25802.1 - 0.084 12.5 0.6 0.17 11.5 0.1 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain Ras PF00071.17 EER25803.1 - 1.5e-39 134.9 0.0 2.4e-39 134.2 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EER25803.1 - 1e-13 51.8 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER25803.1 - 1.5e-11 43.8 0.0 1.5e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER25803.1 - 7.2e-05 22.0 0.0 9.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EER25803.1 - 0.00031 20.2 0.0 0.0015 18.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EER25803.1 - 0.00067 19.6 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EER25803.1 - 0.0011 18.4 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EER25803.1 - 0.0014 18.7 0.0 0.0041 17.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EER25803.1 - 0.0032 16.6 0.0 0.0065 15.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EER25803.1 - 0.0039 17.0 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EER25803.1 - 0.0091 15.1 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EER25803.1 - 0.01 16.1 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EER25803.1 - 0.069 12.8 0.0 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 EER25803.1 - 0.085 12.3 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EER25803.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ADH_N PF08240.7 EER25804.1 - 6.2e-34 116.0 1.8 1e-33 115.3 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER25804.1 - 4.8e-21 74.6 0.2 8.9e-21 73.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER25804.1 - 0.00058 20.7 0.0 0.0011 19.8 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EER25804.1 - 0.0052 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EER25804.1 - 0.031 13.8 1.0 0.068 12.7 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EER25804.1 - 0.031 13.6 0.1 0.05 12.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FtsJ PF01728.14 EER25804.1 - 0.037 13.9 0.1 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EER25804.1 - 0.1 11.7 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) 2-Hacid_dh_C PF02826.14 EER25804.1 - 0.14 11.3 0.1 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glyco_hydro_2 PF00703.16 EER25805.1 - 1e-09 38.8 0.0 3.9e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EER25805.1 - 5.7e-09 35.7 0.3 1.4e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EER25805.1 - 2.6e-05 23.2 0.1 4.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain FAD-oxidase_C PF02913.14 EER25806.1 - 1.2e-56 191.7 0.0 2e-56 191.0 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EER25806.1 - 9.6e-38 128.7 0.0 1.6e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain bZIP_1 PF00170.16 EER25807.1 - 4.4e-06 26.5 1.2 8.9e-06 25.5 0.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Nrf1_DNA-bind PF10491.4 EER25807.1 - 0.15 11.2 1.5 5.4 6.0 0.2 2.3 2 0 0 2 2 2 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 TipAS PF07739.8 EER25808.1 - 0.63 10.3 4.8 8.6 6.7 1.9 2.4 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Na_Ca_ex PF01699.19 EER25809.1 - 1.4e-36 125.1 34.1 8e-23 80.5 9.4 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DRY_EERY PF09750.4 EER25809.1 - 1 9.4 4.2 1.1 9.3 1.4 2.2 1 1 0 1 1 1 0 Alternative splicing regulator Het-C PF07217.6 EER25810.1 - 2.1e-264 878.3 0.0 3.8e-264 877.4 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C MIP-T3 PF10243.4 EER25810.1 - 0.17 10.2 34.5 0.26 9.7 23.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 F-box PF00646.28 EER25811.1 - 0.0002 20.9 0.3 0.00074 19.1 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER25811.1 - 0.015 15.0 0.3 0.044 13.5 0.2 1.8 1 0 0 1 1 1 0 F-box-like Clr5 PF14420.1 EER25812.1 - 4.4e-22 77.7 3.0 4.4e-22 77.7 2.1 2.0 2 0 0 2 2 2 1 Clr5 domain Sensor PF13796.1 EER25812.1 - 1.5 8.4 3.4 1.9 8.0 0.7 2.1 2 0 0 2 2 2 0 Putative sensor Phytase-like PF13449.1 EER25814.1 - 8.1e-27 94.3 0.0 1.2e-26 93.8 0.0 1.4 1 0 0 1 1 1 1 Esterase-like activity of phytase AA_permease_N PF08403.5 EER25816.1 - 0.011 15.0 1.2 0.011 15.0 0.8 1.9 2 0 0 2 2 2 0 Amino acid permease N-terminal WBS_methylT PF12589.3 EER25816.1 - 0.64 10.5 8.8 1.4 9.4 0.0 3.5 3 1 0 3 3 3 0 Methyltransferase involved in Williams-Beuren syndrome Coatomer_WDAD PF04053.9 EER25817.1 - 8.8e-147 489.4 0.0 1.9e-146 488.3 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EER25817.1 - 2.8e-51 169.6 16.5 4.9e-09 35.7 0.3 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat eIF2A PF08662.6 EER25817.1 - 0.00085 19.0 0.1 0.74 9.4 0.0 3.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.15 EER25817.1 - 0.0037 16.8 0.0 0.017 14.7 0.0 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS Nup160 PF11715.3 EER25817.1 - 0.022 12.9 9.5 0.54 8.3 0.0 3.9 2 1 1 5 5 5 0 Nucleoporin Nup120/160 Evr1_Alr PF04777.8 EER25818.1 - 1.1e-29 102.1 2.0 1.1e-29 102.1 1.4 1.6 2 0 0 2 2 2 1 Erv1 / Alr family DEK_C PF08766.6 EER25819.1 - 0.0027 17.4 0.2 0.035 13.8 0.0 2.5 2 0 0 2 2 2 1 DEK C terminal domain Adaptin_N PF01602.15 EER25820.1 - 2.9e-148 494.4 3.2 3.8e-148 494.0 2.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EER25820.1 - 2.7e-30 105.5 0.1 1.4e-26 93.4 0.1 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EER25820.1 - 2.1e-17 63.1 2.5 3.1e-05 24.1 0.0 5.7 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.17 EER25820.1 - 2.4e-11 42.6 1.5 0.018 15.0 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EER25820.1 - 1.6e-06 28.4 0.0 2.4 8.7 0.0 6.4 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EER25820.1 - 0.0017 17.7 0.8 1.9 7.7 0.0 3.9 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.18 EER25820.1 - 0.0078 16.0 0.9 26 4.8 0.0 5.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Cohesin_HEAT PF12765.2 EER25820.1 - 0.022 14.7 0.1 6.4 6.8 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion AF0941-like PF14591.1 EER25820.1 - 0.036 14.1 1.5 0.11 12.5 1.0 1.8 1 0 0 1 1 1 0 AF0941-like PDCD2_C PF04194.8 EER25820.1 - 0.12 12.0 0.1 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain CAAP1 PF15335.1 EER25820.1 - 0.14 12.4 0.4 0.94 9.7 0.1 2.5 2 0 0 2 2 2 0 Caspase activity and apoptosis inhibitor 1 TLD PF07534.11 EER25821.1 - 1.4e-05 25.0 0.0 2.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 TLD VID27 PF08553.5 EER25822.1 - 0 1118.4 0.1 0 1118.1 0.1 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein tRNA_m1G_MT PF01746.16 EER25823.1 - 1.4e-32 112.7 0.3 1.6e-23 83.2 0.0 2.3 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase CAF-1_p150 PF11600.3 EER25823.1 - 0.32 10.3 20.0 0.011 15.0 8.1 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal GRIM-19 PF06212.7 EER25824.1 - 4.6e-24 84.5 0.1 8.7e-24 83.6 0.1 1.4 1 1 0 1 1 1 1 GRIM-19 protein Xpo1 PF08389.7 EER25825.1 - 3.9e-08 33.3 6.9 6.6e-05 22.8 0.0 4.4 4 0 0 4 4 4 3 Exportin 1-like protein IBN_N PF03810.14 EER25825.1 - 0.031 14.1 0.8 2.4 8.1 0.0 3.6 3 0 0 3 3 3 0 Importin-beta N-terminal domain HEAT_2 PF13646.1 EER25825.1 - 0.067 13.4 3.4 0.2 11.9 0.1 3.5 4 1 0 4 4 4 0 HEAT repeats Cellulase PF00150.13 EER25826.1 - 3.2e-07 29.8 4.7 9.6e-05 21.7 1.8 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EER25826.1 - 0.0096 15.0 0.1 2.8 6.9 0.0 2.2 2 0 0 2 2 2 2 Beta-galactosidase TPR_11 PF13414.1 EER25827.1 - 6.2e-46 153.9 39.0 9.1e-09 34.8 0.0 13.7 12 2 2 14 14 14 9 TPR repeat TPR_14 PF13428.1 EER25827.1 - 1.4e-30 102.9 36.5 9.7e-06 25.7 0.1 17.6 15 5 5 20 20 18 6 Tetratricopeptide repeat TPR_17 PF13431.1 EER25827.1 - 4.4e-30 101.3 15.0 0.043 14.0 0.0 16.1 18 0 0 18 18 16 6 Tetratricopeptide repeat TPR_2 PF07719.12 EER25827.1 - 7.8e-30 100.3 48.0 0.00036 20.2 0.0 18.1 21 0 0 21 21 19 7 Tetratricopeptide repeat TPR_16 PF13432.1 EER25827.1 - 2.5e-27 94.8 36.0 4e-05 24.1 0.5 12.8 13 2 2 15 15 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 EER25827.1 - 1e-26 92.6 38.3 1.4e-09 37.7 0.0 12.4 6 3 8 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.1 EER25827.1 - 8e-26 90.1 21.5 6.7e-07 29.5 0.2 11.8 11 1 1 12 12 12 6 Tetratricopeptide repeat TPR_1 PF00515.23 EER25827.1 - 1.7e-25 87.4 34.5 7e-05 22.2 0.1 15.4 17 0 0 17 17 16 5 Tetratricopeptide repeat TPR_8 PF13181.1 EER25827.1 - 8.4e-25 84.6 26.5 0.063 13.0 0.0 13.9 15 1 1 16 16 14 7 Tetratricopeptide repeat TPR_6 PF13174.1 EER25827.1 - 2.7e-13 49.4 32.6 0.0028 17.9 0.0 15.0 18 0 0 18 18 17 3 Tetratricopeptide repeat TPR_7 PF13176.1 EER25827.1 - 3e-10 39.1 27.0 0.00022 20.8 0.1 12.2 14 1 0 14 14 13 2 Tetratricopeptide repeat Apc3 PF12895.2 EER25827.1 - 1.9e-08 34.3 20.8 0.062 13.4 0.0 8.0 8 1 1 9 9 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EER25827.1 - 3.9e-05 23.3 8.3 0.77 9.6 0.2 7.3 6 1 0 7 7 7 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EER25827.1 - 0.00079 18.7 1.8 0.0014 17.9 0.1 2.3 2 0 0 2 2 2 1 Coatomer epsilon subunit PPTA PF01239.17 EER25827.1 - 0.022 14.1 0.6 39 3.8 0.0 4.3 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat TPR_10 PF13374.1 EER25827.1 - 0.052 13.4 19.4 2.2 8.3 0.1 8.5 9 0 0 9 9 8 0 Tetratricopeptide repeat BTAD PF03704.12 EER25827.1 - 0.7 10.1 21.2 0.32 11.2 0.5 5.1 5 1 1 6 6 5 0 Bacterial transcriptional activator domain DUF1767 PF08585.7 EER25828.1 - 2.5e-17 62.9 0.1 3.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Vps51 PF08700.6 EER25829.1 - 3.2e-25 87.7 0.0 1e-24 86.1 0.0 1.8 2 0 0 2 2 2 1 Vps51/Vps67 COG5 PF10392.4 EER25829.1 - 0.0013 18.7 0.1 0.0032 17.4 0.0 1.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Dor1 PF04124.7 EER25829.1 - 0.013 13.9 0.2 0.017 13.6 0.1 1.2 1 0 0 1 1 1 0 Dor1-like family FlgN PF05130.7 EER25829.1 - 0.59 10.3 3.7 1.4 9.2 0.1 2.4 1 1 1 2 2 2 0 FlgN protein WD40 PF00400.27 EER25830.1 - 0.00084 19.1 3.6 0.21 11.5 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat SAC3_GANP PF03399.11 EER25831.1 - 1.4e-25 90.0 0.0 2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EER25831.1 - 1.6e-21 76.5 0.0 3.2e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Med5 PF08689.5 EER25831.1 - 0.079 10.6 0.0 0.089 10.4 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit Med5 AIG2_2 PF13772.1 EER25833.1 - 0.00042 20.3 0.0 0.0085 16.1 0.0 2.3 1 1 0 1 1 1 1 AIG2-like family eIF-5_eIF-2B PF01873.12 EER25836.1 - 9.9e-45 151.2 0.2 1.6e-44 150.5 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Strep_67kDa_ant PF06100.6 EER25836.1 - 0.034 12.5 1.0 0.048 12.0 0.7 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Lar_restr_allev PF14354.1 EER25836.1 - 0.099 12.9 0.7 0.32 11.3 0.5 1.9 1 1 0 1 1 1 0 Restriction alleviation protein Lar DUF2201_N PF13203.1 EER25836.1 - 0.39 9.8 5.7 0.57 9.3 4.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2413 PF10310.4 EER25836.1 - 1.3 7.8 9.5 1.8 7.2 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Arc_trans_TRASH PF08394.5 EER25836.1 - 1.4 9.0 7.1 1.2 9.4 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain AIM24 PF01987.12 EER25837.1 - 1e-58 198.3 0.4 1.2e-58 198.1 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Abhydrolase_6 PF12697.2 EER25838.1 - 5.1e-13 49.4 0.3 5.9e-13 49.2 0.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EER25838.1 - 5.8e-05 22.8 0.0 7.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EER25838.1 - 0.00026 20.7 0.0 0.0003 20.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family SH3_1 PF00018.23 EER25839.1 - 7.9e-15 53.9 0.0 1.2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EER25839.1 - 6.3e-14 51.2 0.0 1.1e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EER25839.1 - 7e-09 35.0 0.0 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.4 EER25839.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MBF1 PF08523.5 EER25840.1 - 1.9e-26 91.8 0.4 4.2e-26 90.7 0.2 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EER25840.1 - 1.2e-12 47.4 0.1 1.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EER25840.1 - 2.8e-06 27.4 0.0 6.5e-06 26.2 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.2 EER25840.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain Iso_dh PF00180.15 EER25841.1 - 5e-69 232.8 0.0 5.9e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FTHFS PF01268.14 EER25842.1 - 2.6e-256 850.9 0.3 3.9e-256 850.4 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EER25842.1 - 2.8e-68 228.0 1.1 2.8e-68 228.0 0.7 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EER25842.1 - 9.7e-38 128.8 0.1 3e-37 127.2 0.1 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 EER25842.1 - 0.024 14.4 0.2 3.7 7.3 0.1 3.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GTP_EFTU PF00009.22 EER25842.1 - 0.026 13.9 0.1 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 EER25843.1 - 1e-29 101.2 1.2 3.8e-08 32.9 0.0 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat Gmad1 PF10647.4 EER25843.1 - 0.00023 20.6 0.3 0.00048 19.6 0.3 1.4 1 1 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Pyr_redox_2 PF07992.9 EER25843.1 - 0.031 14.1 0.0 5.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1708 PF08101.6 EER25844.1 - 2.5e-157 524.0 0.0 3.2e-157 523.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DUF3602 PF12223.3 EER25845.1 - 3.1e-15 56.2 3.8 7.5e-12 45.4 0.8 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) Mito_carr PF00153.22 EER25846.1 - 1.4e-49 165.7 5.7 1.9e-19 69.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 EER25847.1 - 1.1e-06 28.3 0.0 0.25 11.1 0.0 3.2 2 1 1 3 3 3 3 CBS domain Zeta_toxin PF06414.7 EER25847.1 - 0.061 12.4 0.0 0.087 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MFS_2 PF13347.1 EER25848.1 - 1.6e-11 43.2 12.2 1.6e-11 43.2 8.4 2.5 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 EER25848.1 - 0.24 11.2 0.0 0.24 11.2 0.0 3.7 4 0 0 4 4 4 0 MFS_1 like family G6PD_C PF02781.11 EER25849.1 - 1.1e-135 451.2 0.0 1.4e-135 450.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EER25849.1 - 3.8e-65 219.5 0.0 6.9e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain IDO PF01231.13 EER25849.1 - 0.096 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase MFS_1 PF07690.11 EER25850.1 - 1.1e-48 165.7 54.8 8.7e-48 162.8 38.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EER25850.1 - 1.8e-20 72.6 16.9 3.1e-20 71.9 11.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER25850.1 - 3e-11 42.5 14.8 3e-11 42.5 10.3 3.7 2 2 2 4 4 4 3 Sugar (and other) transporter OATP PF03137.15 EER25850.1 - 0.75 7.7 10.6 0.14 10.1 0.8 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Glyoxalase_2 PF12681.2 EER25851.1 - 9.3e-07 29.4 0.0 1.3e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EER25851.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.7 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily EF-hand_1 PF00036.27 EER25852.1 - 1.4e-20 70.9 4.2 3.9e-06 25.7 0.1 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EER25852.1 - 2.1e-18 64.4 2.2 0.0001 21.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EER25852.1 - 2.7e-17 62.1 3.2 4.5e-07 29.3 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EER25852.1 - 9.9e-17 60.8 1.6 2.1e-08 34.1 0.5 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EER25852.1 - 1.2e-10 40.2 2.5 0.00032 19.8 0.1 4.3 4 1 0 4 4 4 3 EF hand ChaC PF04752.7 EER25853.1 - 1.8e-28 99.7 0.0 2.8e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.17 EER25854.1 - 7.1e-25 86.4 0.1 8.8e-25 86.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER25854.1 - 3.6e-18 65.3 0.0 4.5e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER25854.1 - 1.3e-10 40.9 0.0 1.7e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EER25854.1 - 0.028 14.2 0.1 0.046 13.5 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif DUF2306 PF10067.4 EER25856.1 - 3.2e-12 46.4 9.7 9e-12 45.0 6.7 1.8 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 EER25856.1 - 0.027 14.4 0.6 0.027 14.4 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF420) LGT PF01790.13 EER25856.1 - 0.05 12.5 9.3 0.021 13.7 0.9 2.3 2 0 0 2 2 2 0 Prolipoprotein diacylglyceryl transferase DUF997 PF06196.7 EER25856.1 - 1.1 8.8 5.4 1.6 8.3 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF997) PrgI PF12666.2 EER25856.1 - 8.5 6.6 9.3 0.52 10.4 1.4 2.6 1 1 1 2 2 2 0 PrgI family protein FokI_C PF02980.11 EER25857.1 - 0.036 13.7 0.0 2.4 7.7 0.0 3.1 3 0 0 3 3 3 0 Restriction endonuclease FokI, catalytic domain TBCC PF07986.7 EER25858.1 - 4e-29 100.4 0.7 6.4e-29 99.7 0.5 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C LdpA_C PF12617.3 EER25859.1 - 0.15 11.3 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 Iron-Sulfur binding protein C terminal RrnaAD PF00398.15 EER25859.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase JAB PF01398.16 EER25860.1 - 1.7e-14 53.4 0.0 3.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EER25860.1 - 3.4e-07 30.2 0.2 5.8e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EER25860.1 - 1e-05 25.0 0.0 2.6e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MIT PF04212.13 EER25860.1 - 0.014 15.3 0.1 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF605 PF04652.11 EER25860.1 - 2.2 7.6 13.3 3.2 7.0 9.2 1.3 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EER25862.1 - 9.5e-14 51.1 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25862.1 - 7.6e-08 31.7 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER25862.1 - 0.0029 17.3 0.5 0.0055 16.4 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fungal_trans PF04082.13 EER25863.1 - 5.9e-15 54.8 0.2 2.4e-14 52.8 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER25863.1 - 8.4e-08 31.9 10.2 8.4e-08 31.9 7.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EER25864.1 - 1.3e-33 116.3 3.6 1.7e-33 115.8 2.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER25864.1 - 8.3e-20 70.7 9.6 1e-19 70.4 6.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily APH PF01636.18 EER25865.1 - 2.3e-17 63.5 0.0 2e-16 60.4 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family SRF-TF PF00319.13 EER25866.1 - 1.7e-23 81.5 0.2 2.4e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribosomal_L35Ae PF01247.13 EER25867.1 - 1.3e-42 143.5 0.5 1.5e-42 143.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EER25867.1 - 0.0007 19.4 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.4 EER25868.1 - 2.1e-21 76.1 0.1 2.1e-21 76.1 0.0 3.2 3 0 0 3 3 3 1 Uncharacterised protein (DUF2406) GET2 PF08690.5 EER25868.1 - 9.2 5.4 7.9 1.3 8.1 0.9 2.2 2 0 0 2 2 2 0 GET complex subunit GET2 VMA21 PF09446.5 EER25869.1 - 2.5e-12 46.5 6.8 3.2e-12 46.1 4.7 1.1 1 0 0 1 1 1 1 VMA21-like domain EmrE PF13536.1 EER25869.1 - 0.044 13.9 0.1 0.057 13.6 0.1 1.1 1 0 0 1 1 1 0 Multidrug resistance efflux transporter SNF2_N PF00176.18 EER25870.1 - 4.9e-58 196.2 0.0 7.3e-58 195.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER25870.1 - 2.1e-14 53.1 0.0 5.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25870.1 - 9e-07 28.8 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EER25870.1 - 1.9e-06 27.4 0.0 5e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Peptidase_M28 PF04389.12 EER25871.1 - 2.6e-36 125.0 0.1 4.7e-36 124.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EER25871.1 - 4.3e-20 71.2 0.3 5.6e-19 67.7 0.1 2.6 3 0 0 3 3 3 1 PA domain Dus PF01207.12 EER25872.1 - 1.3e-41 142.4 0.0 2.6e-41 141.4 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.14 EER25873.1 - 3.2e-51 172.8 0.3 4.4e-51 172.4 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec20 PF03908.8 EER25874.1 - 8.1e-17 60.7 1.8 8.1e-17 60.7 1.3 2.1 2 0 0 2 2 2 1 Sec20 AAA PF00004.24 EER25875.1 - 2.6e-15 56.7 0.0 1.1e-14 54.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EER25875.1 - 4.3e-13 49.2 0.0 2.1e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EER25875.1 - 1.2e-11 44.0 0.0 6.8e-09 34.9 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EER25875.1 - 3.8e-10 39.6 0.0 7.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EER25875.1 - 8.7e-07 29.1 0.0 0.00016 21.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EER25875.1 - 5.5e-06 25.5 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EER25875.1 - 1.9e-05 24.2 0.0 6.1e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EER25875.1 - 6.7e-05 22.5 0.0 0.00013 21.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER25875.1 - 7.4e-05 22.8 0.1 0.0023 17.9 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EER25875.1 - 0.00029 20.0 0.1 0.016 14.3 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EER25875.1 - 0.00051 19.9 0.0 0.00092 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EER25875.1 - 0.00077 18.5 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EER25875.1 - 0.0028 17.2 2.1 0.0034 16.9 0.3 2.1 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EER25875.1 - 0.0041 16.6 0.0 0.013 14.9 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 EER25875.1 - 0.0049 17.2 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EER25875.1 - 0.0062 15.9 0.0 0.046 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EER25875.1 - 0.009 15.7 0.2 0.11 12.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EER25875.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DNA_pol3_delta PF06144.8 EER25875.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_10 PF12846.2 EER25875.1 - 0.017 14.5 0.1 0.43 9.9 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EER25875.1 - 0.02 15.7 0.0 0.06 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EER25875.1 - 0.03 14.2 0.0 0.099 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EER25875.1 - 0.031 14.5 0.0 0.1 12.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EER25875.1 - 0.036 13.6 0.0 0.45 10.1 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 EER25875.1 - 0.056 12.2 0.0 0.95 8.1 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain DEAD PF00270.24 EER25875.1 - 0.075 12.5 0.0 0.79 9.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.12 EER25875.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF1746 PF08508.5 EER25877.1 - 6.4e-40 135.7 2.2 9.2e-40 135.2 1.5 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) SR-25 PF10500.4 EER25877.1 - 0.4 10.1 7.4 7.5 5.9 0.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CLP_protease PF00574.18 EER25878.1 - 5.4e-75 251.0 0.0 6.8e-75 250.7 0.0 1.0 1 0 0 1 1 1 1 Clp protease Clr5 PF14420.1 EER25878.1 - 0.0073 16.1 0.6 0.014 15.2 0.4 1.4 1 0 0 1 1 1 1 Clr5 domain Hydrolase_6 PF13344.1 EER25880.1 - 1.7e-29 101.6 0.0 2.7e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER25880.1 - 6.6e-13 48.1 0.0 1.9e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EER25880.1 - 2e-10 41.4 0.0 3.1e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EER25880.1 - 1.2e-05 25.5 0.1 0.015 15.5 0.0 2.9 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EER25880.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Sugar_tr PF00083.19 EER25881.1 - 3.6e-44 151.0 9.3 4.8e-44 150.6 6.4 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER25881.1 - 6.6e-38 130.3 26.0 4.4e-25 88.1 7.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EER25881.1 - 2.3e-05 23.0 4.9 2.3e-05 23.0 3.4 2.2 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EER25881.1 - 0.006 16.3 0.1 0.28 10.9 0.0 2.9 2 0 0 2 2 2 1 MFS_1 like family HTH_38 PF13936.1 EER25881.1 - 0.095 12.2 0.3 0.44 10.1 0.5 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain UPF0239 PF06783.6 EER25881.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) OppC_N PF12911.2 EER25881.1 - 0.99 8.8 5.1 1.6 8.1 0.0 3.5 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C LacY_symp PF01306.14 EER25881.1 - 7.9 4.9 16.1 0.47 8.9 0.6 2.8 2 2 1 3 3 3 0 LacY proton/sugar symporter Peptidase_M18 PF02127.10 EER25882.1 - 9.8e-160 531.7 0.0 1.1e-159 531.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.27 EER25883.1 - 3.1e-37 125.1 5.7 9.7e-08 31.6 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EER25883.1 - 1.2e-08 34.8 0.3 0.00031 20.5 0.0 3.1 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A E3_binding PF02817.12 EER25884.1 - 1.3e-07 31.1 0.0 8.6e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 e3 binding domain DUF2360 PF10152.4 EER25884.1 - 3.8 7.7 7.6 1.2 9.4 2.3 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) APH PF01636.18 EER25887.1 - 6.3e-11 42.4 0.0 6.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER25887.1 - 3.5e-05 23.4 0.0 5.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EER25887.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EER25887.1 - 0.036 13.2 0.0 0.045 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain DUF2838 PF10998.3 EER25888.1 - 3.1e-46 155.8 11.3 3.1e-46 155.8 7.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) L27_2 PF09045.5 EER25888.1 - 0.039 13.4 0.1 0.99 8.9 0.0 3.0 3 0 0 3 3 3 0 L27_2 Bot1p PF12298.3 EER25888.1 - 0.081 12.8 1.7 0.14 12.1 1.2 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein MtrB PF05440.7 EER25888.1 - 0.081 12.9 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B IncA PF04156.9 EER25888.1 - 0.48 9.9 3.4 1.1 8.8 2.4 1.5 1 0 0 1 1 1 0 IncA protein DUF349 PF03993.7 EER25888.1 - 0.55 10.4 6.5 2.5 8.3 4.8 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF883 PF05957.8 EER25888.1 - 3.7 8.0 6.1 98 3.4 0.0 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) SMC_N PF02463.14 EER25889.1 - 2.8e-59 200.0 0.0 1.9e-58 197.2 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EER25889.1 - 7.1e-32 109.8 0.4 5.6e-31 107.0 0.0 2.7 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EER25889.1 - 3.3e-11 43.8 14.6 3.3e-11 43.8 10.1 6.6 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 EER25889.1 - 1.2e-10 41.8 0.2 3.3e-06 27.2 0.0 4.2 3 2 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EER25889.1 - 2.9e-08 33.0 0.0 5.8e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EER25889.1 - 0.0013 18.5 0.0 0.0051 16.6 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Laminin_II PF06009.7 EER25889.1 - 0.015 15.0 0.4 0.015 15.0 0.3 8.7 4 3 6 10 10 10 0 Laminin Domain II TPR_MLP1_2 PF07926.7 EER25889.1 - 0.033 13.9 0.4 0.033 13.9 0.2 8.2 4 2 2 7 7 7 0 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 EER25889.1 - 0.097 12.5 22.2 0.035 13.9 1.2 6.2 5 3 1 6 6 6 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EER25889.1 - 4 6.5 29.3 0.31 10.1 0.7 4.6 3 2 1 5 5 5 0 Reovirus sigma C capsid protein NUDIX PF00293.23 EER25891.1 - 3.5e-12 46.1 0.0 6e-12 45.3 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain GHL12 PF14882.1 EER25891.1 - 0.15 12.1 1.4 0.36 10.9 0.9 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 12 LETM1 PF07766.8 EER25892.1 - 1.2e-104 349.1 0.0 1.9e-104 348.4 0.0 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EER25892.1 - 2.8e-06 26.6 0.1 0.032 13.7 0.0 3.5 3 0 0 3 3 3 3 SAP domain Glyco_hydro_38 PF01074.17 EER25893.1 - 2e-93 312.6 0.3 3.3e-93 311.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EER25893.1 - 3.7e-76 256.7 0.0 7.7e-76 255.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EER25893.1 - 1.3e-26 92.6 0.0 2.9e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain NuA4 PF09340.5 EER25894.1 - 8.3e-27 92.6 0.4 2e-26 91.4 0.0 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Senescence_reg PF04520.8 EER25894.1 - 0.012 16.0 2.1 0.023 15.2 1.5 1.4 1 0 0 1 1 1 0 Senescence regulator Ctr PF04145.10 EER25895.1 - 5.3e-35 120.5 0.1 6.1e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Sensor PF13796.1 EER25895.1 - 0.25 10.9 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Putative sensor Cupin_8 PF13621.1 EER25896.1 - 3.1e-16 59.6 0.1 3.7e-15 56.1 0.1 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EER25896.1 - 3.4e-10 40.1 0.8 8.9e-09 35.5 0.5 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EER25896.1 - 7.8e-06 25.5 0.0 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER25896.1 - 0.0068 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Cupin_4 PF08007.7 EER25896.1 - 0.0085 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein DEAD PF00270.24 EER25897.1 - 9.4e-44 148.8 1.5 1.9e-43 147.9 1.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER25897.1 - 4.7e-28 96.8 0.4 1.4e-27 95.3 0.2 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25897.1 - 0.0005 19.9 0.1 0.0013 18.6 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EER25897.1 - 0.00091 18.8 0.2 0.0022 17.6 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EER25897.1 - 0.0024 17.9 0.0 0.007 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 EER25897.1 - 0.0034 16.4 0.0 0.0076 15.3 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EER25897.1 - 0.013 15.2 0.1 0.038 13.7 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain Helicase_RecD PF05127.9 EER25897.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Helicase CobA_CobO_BtuR PF02572.10 EER25897.1 - 0.074 12.6 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Flavi_DEAD PF07652.9 EER25897.1 - 0.08 12.6 0.1 0.58 9.9 0.1 2.4 1 1 0 1 1 1 0 Flavivirus DEAD domain SNF2_N PF00176.18 EER25897.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain Retrotrans_gag PF03732.12 EER25898.1 - 0.033 14.2 0.1 0.14 12.2 0.0 2.1 2 0 0 2 2 2 0 Retrotransposon gag protein HALZ PF02183.13 EER25898.1 - 0.054 13.2 6.1 0.37 10.5 0.3 3.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper Hemerythrin PF01814.18 EER25898.1 - 0.13 12.4 3.5 0.3 11.2 2.4 1.6 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Reo_sigmaC PF04582.7 EER25898.1 - 0.15 11.1 0.1 0.31 10.1 0.0 1.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 EER25898.1 - 8 6.0 8.8 4.8 6.7 0.1 2.9 2 1 1 3 3 3 0 IncA protein FAA_hydrolase PF01557.13 EER25899.1 - 6.9e-57 192.4 0.0 8.6e-57 192.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PWI PF01480.12 EER25901.1 - 1.1e-29 102.3 0.4 6.7e-29 99.8 0.0 2.0 2 0 0 2 2 2 1 PWI domain Atrophin-1 PF03154.10 EER25901.1 - 0.78 7.8 9.3 0.94 7.5 6.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family EIF4E-T PF10477.4 EER25902.1 - 0.019 13.7 3.4 0.019 13.8 2.4 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E DUF2158 PF09926.4 EER25902.1 - 0.03 13.7 0.2 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized small protein (DUF2158) Pkinase PF00069.20 EER25903.1 - 1.5e-47 161.9 0.0 2.2e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25903.1 - 5.8e-17 61.6 0.0 9.2e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER25903.1 - 0.00081 18.4 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EER25903.1 - 0.011 15.0 0.2 0.023 14.0 0.1 1.5 1 1 0 1 1 1 0 RIO1 family APH PF01636.18 EER25903.1 - 0.035 13.8 2.5 2.1 8.0 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIB43A PF05914.7 EER25904.1 - 0.026 13.1 0.5 0.035 12.7 0.4 1.1 1 0 0 1 1 1 0 RIB43A DUF822 PF05687.8 EER25904.1 - 5.7 7.2 6.7 2 8.7 1.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF822) Ribosomal_S8e PF01201.17 EER25905.1 - 1.5e-28 99.5 3.3 3.9e-28 98.2 2.3 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e Fungal_trans PF04082.13 EER25906.1 - 2.6e-23 82.2 1.4 4e-23 81.6 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER25906.1 - 0.0012 18.7 6.0 0.0022 17.8 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tyrosinase PF00264.15 EER25907.1 - 3.6e-54 184.2 0.3 6.5e-54 183.4 0.2 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Metallophos PF00149.23 EER25908.1 - 1.8e-09 37.2 0.4 1.1e-07 31.5 0.2 2.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Cation_efflux PF01545.16 EER25909.1 - 1e-77 261.0 6.1 4.6e-77 258.8 4.2 1.8 1 1 0 1 1 1 1 Cation efflux family DUF202 PF02656.10 EER25910.1 - 2.4e-15 56.5 1.0 2.4e-15 56.5 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1426 PF07234.6 EER25910.1 - 0.2 11.4 2.6 6.3 6.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) DUF2970 PF11174.3 EER25910.1 - 3.4 7.3 7.6 3.7 7.2 2.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) HemY_N PF07219.8 EER25910.1 - 6.8 6.2 9.4 3.6 7.1 3.1 2.8 3 1 0 3 3 3 0 HemY protein N-terminus AAA PF00004.24 EER25911.1 - 3.9e-38 130.6 0.0 2.5e-13 50.3 0.0 3.7 3 0 0 3 3 3 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER25911.1 - 2.8e-16 59.8 3.5 0.0022 18.1 0.0 6.3 3 3 0 3 3 3 3 AAA domain RuvB_N PF05496.7 EER25911.1 - 1.6e-12 47.0 0.0 9.8e-05 21.5 0.0 3.7 3 0 0 3 3 3 3 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EER25911.1 - 3.1e-12 46.4 0.2 0.0046 16.6 0.0 4.2 4 1 0 4 4 3 3 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EER25911.1 - 4e-12 47.0 0.0 0.0042 17.9 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EER25911.1 - 6.2e-10 38.6 1.0 0.047 13.4 0.0 4.4 5 0 0 5 5 3 3 Part of AAA domain Viral_helicase1 PF01443.13 EER25911.1 - 7.5e-09 35.4 2.1 0.031 13.7 0.0 3.8 4 0 0 4 4 3 3 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 EER25911.1 - 1.8e-08 34.4 1.8 0.081 12.7 0.0 4.0 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 EER25911.1 - 5.5e-08 33.0 0.1 0.32 10.9 0.0 4.5 3 1 0 3 3 3 2 AAA ATPase domain Mg_chelatase PF01078.16 EER25911.1 - 6.1e-08 32.0 0.9 0.5 9.4 0.0 4.7 3 2 2 5 5 5 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EER25911.1 - 2.1e-07 31.0 3.3 0.5 10.3 0.1 5.4 4 1 0 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EER25911.1 - 3.2e-07 29.9 0.3 0.52 9.7 0.0 4.7 3 2 0 3 3 3 2 Sigma-54 interaction domain AAA_2 PF07724.9 EER25911.1 - 6e-07 29.5 0.0 0.061 13.2 0.0 3.9 4 0 0 4 4 3 2 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EER25911.1 - 7e-07 29.3 0.0 1.7 8.8 0.0 4.0 4 0 0 4 4 3 2 RNA helicase Sigma54_activ_2 PF14532.1 EER25911.1 - 1.4e-06 28.3 0.0 0.54 10.3 0.0 3.8 3 0 0 3 3 3 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EER25911.1 - 1.8e-06 27.4 0.1 0.36 10.2 0.0 3.9 4 0 0 4 4 3 2 IstB-like ATP binding protein AAA_25 PF13481.1 EER25911.1 - 2e-06 27.3 0.1 0.31 10.4 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EER25911.1 - 2.3e-06 27.9 5.4 0.14 12.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EER25911.1 - 1e-05 25.2 7.9 0.11 12.1 0.0 4.9 3 3 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EER25911.1 - 3.9e-05 23.2 4.2 2.8 7.3 0.0 5.0 4 1 0 5 5 5 1 AAA-like domain AAA_24 PF13479.1 EER25911.1 - 0.0001 21.9 0.2 3.4 7.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EER25911.1 - 0.0012 18.2 0.0 5.3 6.6 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain MCM PF00493.18 EER25911.1 - 0.0014 17.4 0.1 0.18 10.5 0.0 2.3 2 0 0 2 2 2 1 MCM2/3/5 family NACHT PF05729.7 EER25911.1 - 0.002 17.8 1.5 3.7 7.1 0.0 4.7 5 1 0 5 5 4 1 NACHT domain PhoH PF02562.11 EER25911.1 - 0.0042 16.3 0.2 13 4.9 0.0 3.4 3 0 0 3 3 3 0 PhoH-like protein T2SE PF00437.15 EER25911.1 - 0.0044 15.9 0.0 2 7.2 0.0 3.3 3 0 0 3 3 3 1 Type II/IV secretion system protein Torsin PF06309.6 EER25911.1 - 0.0068 16.3 0.1 15 5.4 0.0 3.5 3 0 0 3 3 3 0 Torsin MobB PF03205.9 EER25911.1 - 0.01 15.5 0.2 18 4.9 0.0 3.5 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EER25911.1 - 0.031 14.0 0.1 8.8 6.0 0.0 3.3 3 0 0 3 3 3 0 NTPase Transpep_BrtH PF14399.1 EER25911.1 - 0.045 13.0 0.0 0.99 8.6 0.0 2.6 2 0 0 2 2 2 0 NlpC/p60-like transpeptidase MADF_DNA_bdg PF10545.4 EER25911.1 - 0.045 13.9 0.0 0.17 12.0 0.0 2.1 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like KaiC PF06745.8 EER25911.1 - 0.046 12.8 0.7 3.9 6.5 0.0 3.1 3 0 0 3 3 3 0 KaiC SRP54 PF00448.17 EER25911.1 - 0.05 13.0 0.6 17 4.7 0.1 3.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ResIII PF04851.10 EER25911.1 - 0.056 13.2 7.8 11 5.7 0.0 5.2 4 2 2 6 6 5 0 Type III restriction enzyme, res subunit APS_kinase PF01583.15 EER25911.1 - 0.077 12.6 0.0 79 2.8 0.0 3.3 3 0 0 3 3 3 0 Adenylylsulphate kinase Guanylate_cyc_2 PF09778.4 EER25911.1 - 0.078 12.1 0.0 2.1 7.5 0.0 2.6 3 0 0 3 3 3 0 Guanylylate cyclase ATP_bind_1 PF03029.12 EER25911.1 - 0.39 10.2 2.5 41 3.6 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EER25911.1 - 0.62 10.3 5.1 40 4.5 0.0 4.1 4 0 0 4 4 3 0 ABC transporter KTI12 PF08433.5 EER25911.1 - 2.1 7.4 7.2 10 5.2 0.0 3.7 4 0 0 4 4 3 0 Chromatin associated protein KTI12 Methyltransf_11 PF08241.7 EER25913.1 - 4.8e-16 59.0 0.3 1.1e-15 57.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER25913.1 - 4.2e-15 55.8 0.0 6.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER25913.1 - 4.5e-14 52.3 0.0 6.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER25913.1 - 1.2e-13 51.3 0.0 1.9e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER25913.1 - 4.8e-13 49.6 0.0 7.7e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER25913.1 - 1.5e-08 34.8 0.0 3.2e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER25913.1 - 3.5e-08 33.4 0.0 6.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER25913.1 - 5.4e-06 25.8 0.0 8.3e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EER25913.1 - 0.00018 20.7 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EER25913.1 - 0.00031 19.9 0.0 0.00043 19.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EER25913.1 - 0.00048 19.7 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 EER25913.1 - 0.00083 18.3 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EER25913.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EER25913.1 - 0.0034 16.5 0.0 0.0065 15.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 EER25913.1 - 0.0081 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase FtsJ PF01728.14 EER25913.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EER25913.1 - 0.012 14.3 0.0 0.022 13.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 EER25913.1 - 0.028 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pox_MCEL PF03291.11 EER25913.1 - 0.033 13.0 0.1 0.11 11.3 0.0 1.8 1 1 0 1 1 1 0 mRNA capping enzyme NodS PF05401.6 EER25913.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.7 EER25913.1 - 0.051 12.9 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FmrO PF07091.6 EER25913.1 - 0.099 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_4 PF02390.12 EER25913.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase DUF647 PF04884.9 EER25913.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis M16C_assoc PF08367.6 EER25914.1 - 1.9e-51 174.2 0.0 3.4e-51 173.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EER25914.1 - 2.6e-25 89.1 0.0 2.5e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EER25914.1 - 1.9e-10 40.6 0.0 2.2e-09 37.2 0.0 2.6 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 EER25915.1 - 8.1e-104 347.0 51.5 8.1e-104 347.0 35.7 1.3 2 0 0 2 2 2 1 Myosin-like coiled-coil protein DHC_N1 PF08385.7 EER25915.1 - 0.00089 17.7 2.8 0.00089 17.7 2.0 3.3 2 2 1 3 3 3 2 Dynein heavy chain, N-terminal region 1 DUF4201 PF13870.1 EER25915.1 - 0.0016 17.9 15.7 0.0016 17.9 10.9 4.6 1 1 4 5 5 5 1 Domain of unknown function (DUF4201) AAA_13 PF13166.1 EER25915.1 - 0.85 8.0 42.0 0.78 8.1 11.9 2.2 1 1 0 2 2 2 0 AAA domain DUF3675 PF12428.3 EER25915.1 - 1.2 9.3 4.3 12 6.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DUF725 PF05267.7 EER25915.1 - 2.5 8.0 8.0 0.23 11.3 1.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF725) HlyD PF00529.15 EER25915.1 - 2.8 7.1 21.9 3 7.0 5.2 2.6 2 1 0 2 2 2 0 HlyD family secretion protein DUF3584 PF12128.3 EER25915.1 - 2.8 5.1 47.2 6.3 3.9 31.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) FliD_N PF02465.13 EER25915.1 - 3.2 8.1 22.6 1.3 9.4 0.8 4.4 2 2 2 4 4 4 0 Flagellar hook-associated protein 2 N-terminus TMF_TATA_bd PF12325.3 EER25915.1 - 9.9 5.9 54.3 0.14 11.8 9.1 4.4 1 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding NMO PF03060.10 EER25916.1 - 7.4e-74 248.8 0.2 8.5e-74 248.6 0.1 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EER25916.1 - 6.5e-06 25.2 0.0 0.00054 18.9 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EER25916.1 - 0.00026 19.9 2.7 0.0004 19.3 1.8 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EER25916.1 - 0.27 10.0 1.8 0.57 9.0 1.3 1.5 1 1 0 1 1 1 0 Conserved region in glutamate synthase Fungal_trans_2 PF11951.3 EER25917.1 - 4.9e-19 68.1 0.4 6.8e-19 67.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER25917.1 - 5.6e-08 32.5 10.3 1.4e-07 31.3 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EER25918.1 - 1.3e-87 294.5 0.0 1.5e-87 294.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Peptidase_M20 PF01546.23 EER25919.1 - 5.2e-06 26.0 0.4 8.9e-06 25.3 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EER25919.1 - 0.00019 21.1 0.1 0.00044 19.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain MFS_1 PF07690.11 EER25920.1 - 4.5e-38 130.8 32.5 4.5e-38 130.8 22.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.1 EER25920.1 - 6.8 6.0 22.1 0.054 12.8 1.2 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) DNA_pol_E_B PF04042.11 EER25921.1 - 4.6e-48 163.2 0.0 6.1e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Proteasome PF00227.21 EER25922.1 - 2.2e-48 164.0 0.2 2.5e-48 163.8 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_5 PF12695.2 EER25923.1 - 1.3e-20 73.6 0.0 1.8e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER25923.1 - 2.5e-18 66.8 0.0 3.6e-17 63.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER25923.1 - 2e-05 24.2 0.0 0.00079 19.0 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EER25923.1 - 2.6e-05 24.0 0.0 0.033 13.9 0.0 2.3 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EER25923.1 - 3.2e-05 23.4 0.0 0.01 15.2 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EER25923.1 - 3.8e-05 23.0 0.0 8.2e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.7 EER25923.1 - 0.00016 20.5 0.0 0.00025 19.9 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) FSH1 PF03959.8 EER25923.1 - 0.00043 19.7 0.0 0.00062 19.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.13 EER25923.1 - 0.001 18.3 0.0 0.72 9.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.7 EER25923.1 - 0.0052 15.3 0.0 0.48 8.8 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EER25923.1 - 0.0079 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EER25923.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase ATP11 PF06644.6 EER25924.1 - 2.2e-86 289.6 0.0 2.6e-86 289.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein PAT1 PF09770.4 EER25924.1 - 3.7 5.6 9.3 4.7 5.3 6.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tropomyosin_1 PF12718.2 EER25925.1 - 1.2e-27 96.4 28.7 1.2e-27 96.4 19.9 1.4 1 1 0 1 1 1 1 Tropomyosin like Myosin_tail_1 PF01576.14 EER25925.1 - 1.2e-06 26.6 30.6 0.0014 16.4 8.4 2.3 1 1 1 2 2 2 2 Myosin tail TMF_DNA_bd PF12329.3 EER25925.1 - 3.2e-06 26.8 7.5 3.2e-06 26.8 5.2 3.3 1 1 0 2 2 1 1 TATA element modulatory factor 1 DNA binding GAS PF13851.1 EER25925.1 - 2.1e-05 23.8 22.5 0.0006 19.0 7.2 2.5 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding HAUS-augmin3 PF14932.1 EER25925.1 - 0.00031 20.0 11.8 0.00031 20.0 8.2 2.0 1 1 1 2 2 2 1 HAUS augmin-like complex subunit 3 DUF1192 PF06698.6 EER25925.1 - 0.00069 19.3 15.1 0.96 9.3 0.9 4.3 3 1 1 4 4 4 1 Protein of unknown function (DUF1192) AAA_13 PF13166.1 EER25925.1 - 0.0014 17.1 16.6 0.0019 16.7 11.5 1.1 1 0 0 1 1 1 1 AAA domain Tropomyosin PF00261.15 EER25925.1 - 0.0032 16.5 28.9 0.0088 15.1 20.0 1.7 1 1 0 1 1 1 1 Tropomyosin HALZ PF02183.13 EER25925.1 - 0.0039 16.8 1.9 0.0039 16.8 1.3 3.8 4 1 0 4 4 3 1 Homeobox associated leucine zipper Rootletin PF15035.1 EER25925.1 - 0.0081 16.1 4.5 0.0081 16.1 3.1 2.2 1 1 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 EER25925.1 - 0.01 15.0 2.1 0.25 10.4 0.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Lectin_N PF03954.9 EER25925.1 - 0.01 15.2 5.5 0.047 13.0 0.3 2.7 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF342 PF03961.8 EER25925.1 - 0.013 13.9 21.6 0.072 11.5 3.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF869 PF05911.6 EER25925.1 - 0.024 12.9 18.8 0.05 11.8 13.0 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) TPD52 PF04201.10 EER25925.1 - 0.026 14.2 3.5 0.026 14.2 2.4 2.7 1 1 1 3 3 3 0 Tumour protein D52 family Seryl_tRNA_N PF02403.17 EER25925.1 - 0.03 14.3 26.0 0.18 11.8 7.5 3.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 EER25925.1 - 0.041 13.6 10.9 0.41 10.4 1.0 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) EzrA PF06160.7 EER25925.1 - 0.05 11.7 21.0 0.036 12.2 2.3 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA bZIP_1 PF00170.16 EER25925.1 - 0.052 13.5 1.4 0.052 13.5 1.0 4.1 2 2 3 5 5 4 0 bZIP transcription factor WD40_alt PF14077.1 EER25925.1 - 0.055 13.1 1.3 0.055 13.1 0.9 2.7 4 0 0 4 4 2 0 Alternative WD40 repeat motif Hemerythrin PF01814.18 EER25925.1 - 0.057 13.5 10.4 3.4 7.8 3.1 3.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain DUF3450 PF11932.3 EER25925.1 - 0.06 12.6 24.0 0.063 12.5 2.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Laminin_II PF06009.7 EER25925.1 - 0.061 13.0 16.1 0.11 12.2 5.4 2.5 1 1 1 2 2 2 0 Laminin Domain II MutS_III PF05192.13 EER25925.1 - 0.064 13.0 8.9 0.077 12.7 6.2 1.1 1 0 0 1 1 1 0 MutS domain III Prefoldin_2 PF01920.15 EER25925.1 - 0.092 12.5 27.4 0.72 9.6 8.6 3.5 1 1 2 3 3 3 0 Prefoldin subunit ADIP PF11559.3 EER25925.1 - 0.098 12.5 27.1 0.046 13.6 3.5 2.8 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EER25925.1 - 0.1 12.1 27.3 3.7 7.0 18.9 2.1 1 1 0 1 1 1 0 IncA protein DUF4200 PF13863.1 EER25925.1 - 0.14 12.1 29.9 0.28 11.1 4.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 EER25925.1 - 0.14 12.4 10.0 1.6e+03 -0.6 6.9 3.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DASH_Dad3 PF08656.5 EER25925.1 - 0.14 11.8 7.6 2.5 7.8 0.2 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad3 BLOC1_2 PF10046.4 EER25925.1 - 0.16 12.1 15.1 1.1 9.4 2.9 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EER25925.1 - 0.23 10.9 27.9 0.062 12.7 4.9 3.8 1 1 2 3 3 3 0 Septum formation initiator Syntaxin-6_N PF09177.6 EER25925.1 - 0.24 11.8 15.8 0.62 10.5 3.2 3.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF972 PF06156.8 EER25925.1 - 0.26 11.6 21.4 0.27 11.5 2.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Filament PF00038.16 EER25925.1 - 0.27 10.6 24.5 0.18 11.2 4.0 2.1 1 1 0 1 1 1 0 Intermediate filament protein Lebercilin PF15619.1 EER25925.1 - 0.28 10.5 28.2 6.4 6.1 19.6 2.6 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF4407 PF14362.1 EER25925.1 - 0.38 9.6 23.4 1.2 8.0 16.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.8 EER25925.1 - 0.4 11.4 16.8 3 8.6 1.4 3.1 1 1 0 2 2 2 0 Occludin homology domain Striatin PF08232.7 EER25925.1 - 0.43 10.8 22.1 12 6.1 15.3 2.2 1 1 0 1 1 1 0 Striatin family Allexi_40kDa PF05549.6 EER25925.1 - 0.45 9.7 7.4 0.89 8.7 1.2 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein CCDC155 PF14662.1 EER25925.1 - 0.46 10.0 29.1 0.12 11.9 6.1 2.9 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Fib_alpha PF08702.5 EER25925.1 - 0.47 10.5 14.2 0.96 9.5 3.6 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 EER25925.1 - 0.5 9.9 27.3 0.34 10.5 3.6 2.3 1 1 1 2 2 2 0 Mnd1 family TPR_MLP1_2 PF07926.7 EER25925.1 - 0.57 9.9 30.1 1.4e+02 2.1 20.9 2.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ERM PF00769.14 EER25925.1 - 0.57 9.6 31.1 1.9 7.9 5.3 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4600 PF15372.1 EER25925.1 - 0.59 10.3 20.5 0.085 13.0 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4600) Snapin_Pallidin PF14712.1 EER25925.1 - 0.62 10.4 16.3 3.1 8.1 0.5 3.2 1 1 1 3 3 3 0 Snapin/Pallidin THOC7 PF05615.8 EER25925.1 - 0.69 10.1 24.8 1.2 9.3 7.1 2.9 1 1 2 3 3 3 0 Tho complex subunit 7 DUF3166 PF11365.3 EER25925.1 - 0.73 10.3 12.1 0.26 11.7 5.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) FlaC_arch PF05377.6 EER25925.1 - 0.97 9.3 10.8 1.9 8.4 0.3 3.7 2 2 1 4 4 4 0 Flagella accessory protein C (FlaC) IFT57 PF10498.4 EER25925.1 - 1.4 7.6 18.4 3.3 6.3 6.4 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 CENP-F_leu_zip PF10473.4 EER25925.1 - 1.4 8.7 29.6 2 8.2 5.7 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TBPIP PF07106.8 EER25925.1 - 1.4 8.4 20.2 0.62 9.5 2.7 2.5 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sipho_Gp157 PF05565.6 EER25925.1 - 1.5 8.3 17.1 1.3 8.5 5.7 2.5 1 1 2 3 3 3 0 Siphovirus Gp157 DUF2730 PF10805.3 EER25925.1 - 1.8 8.3 8.6 3.1 7.5 0.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) WXG100 PF06013.7 EER25925.1 - 1.9 8.5 13.9 3.2 7.8 1.3 3.5 1 1 2 3 3 3 0 Proteins of 100 residues with WXG APG6 PF04111.7 EER25925.1 - 2 7.4 28.7 2.6 7.0 7.6 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4140 PF13600.1 EER25925.1 - 2 8.8 24.2 7 7.1 2.7 3.5 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) BRE1 PF08647.6 EER25925.1 - 2.2 8.2 24.9 0.63 10.0 2.2 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.7 EER25925.1 - 2.4 7.9 7.7 70 3.2 5.3 2.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TarH PF02203.10 EER25925.1 - 2.7 7.7 18.6 2.4 7.9 2.0 2.1 1 1 1 2 2 2 0 Tar ligand binding domain homologue YlqD PF11068.3 EER25925.1 - 3.2 7.8 24.7 0.17 11.8 3.5 2.4 1 1 1 2 2 2 0 YlqD protein DivIVA PF05103.8 EER25925.1 - 3.2 7.8 26.2 0.73 9.8 2.3 2.7 1 1 1 2 2 2 0 DivIVA protein LURAP PF14854.1 EER25925.1 - 3.4 7.3 10.0 12 5.6 0.3 3.1 2 1 1 3 3 3 0 Leucine rich adaptor protein Spectrin PF00435.16 EER25925.1 - 4.6 7.5 25.7 2.6 8.3 3.2 2.6 1 1 1 2 2 2 0 Spectrin repeat DUF4337 PF14235.1 EER25925.1 - 4.8 6.9 25.5 1.8 8.4 10.8 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4337) Complex1_LYR_2 PF13233.1 EER25925.1 - 5 7.6 10.1 19 5.8 7.0 1.9 1 1 0 1 1 1 0 Complex1_LYR-like CDC37_N PF03234.9 EER25925.1 - 5.2 7.3 17.6 7.7 6.8 12.2 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding PspA_IM30 PF04012.7 EER25925.1 - 6.7 6.0 33.2 1.7 7.9 3.7 2.2 1 1 1 2 2 2 0 PspA/IM30 family TMPIT PF07851.8 EER25925.1 - 9 5.2 11.8 0.41 9.6 1.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein Nop25 PF09805.4 EER25926.1 - 7e-37 126.5 10.7 7e-37 126.5 7.4 2.6 2 1 1 3 3 3 1 Nucleolar protein 12 (25kDa) ATP-synt_S1 PF05827.7 EER25927.1 - 5.6e-43 147.2 0.0 2.5e-42 145.1 0.0 1.8 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Ank_2 PF12796.2 EER25928.1 - 1.6e-70 233.4 15.0 1e-15 57.8 0.4 7.1 1 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EER25928.1 - 6.1e-58 189.8 11.2 3.1e-06 26.7 0.0 12.9 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 EER25928.1 - 2e-41 139.6 11.5 5.4e-07 29.9 0.0 9.9 4 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER25928.1 - 2.4e-38 126.3 9.5 0.00056 19.8 0.0 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank_5 PF13857.1 EER25928.1 - 4.9e-30 102.8 19.1 2.1e-06 27.7 0.2 8.0 3 2 7 10 10 10 9 Ankyrin repeats (many copies) HNH_2 PF13391.1 EER25929.1 - 1.1e-16 60.4 0.4 1.4e-15 56.7 0.1 2.3 2 0 0 2 2 2 1 HNH endonuclease Glyco_hydro_3 PF00933.16 EER25930.1 - 2.3e-56 190.9 0.0 3.4e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EER25930.1 - 3.5e-22 78.2 0.2 2.2e-10 40.4 0.0 3.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER25930.1 - 4.3e-18 65.2 0.0 3.1e-10 40.0 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER25930.1 - 1.1e-14 54.5 0.0 3.2e-08 33.6 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER25930.1 - 7.7e-09 35.1 0.1 0.00095 18.8 0.0 2.7 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_9 PF13527.1 EER25930.1 - 1.9e-06 27.7 0.0 0.073 12.9 0.0 2.8 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EER25930.1 - 0.00033 20.2 0.0 0.00065 19.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_6 PF13480.1 EER25930.1 - 0.00068 19.6 0.1 0.012 15.5 0.1 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EER25930.1 - 0.0014 18.2 0.0 0.024 14.2 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER25930.1 - 0.0031 17.3 0.1 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Pyr_redox_2 PF07992.9 EER25931.1 - 1e-20 74.4 3.7 2.8e-18 66.5 2.1 4.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER25931.1 - 6.4e-12 45.7 0.9 1e-10 41.8 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER25931.1 - 3e-09 37.2 0.6 3.2e-05 24.0 0.1 3.3 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EER25931.1 - 9.3e-09 34.6 1.9 0.00092 18.2 0.1 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EER25931.1 - 4.2e-07 29.2 0.7 1.1e-05 24.5 0.1 2.7 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EER25931.1 - 6.7e-06 25.9 3.5 0.31 10.8 0.0 4.7 5 0 0 5 5 5 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EER25931.1 - 9.1e-06 24.8 1.7 0.016 14.1 0.1 3.4 3 1 0 4 4 4 2 Lycopene cyclase protein Trp_halogenase PF04820.9 EER25931.1 - 1.8e-05 23.5 0.8 0.73 8.3 0.0 3.3 2 1 1 3 3 3 3 Tryptophan halogenase DUF4147 PF13660.1 EER25931.1 - 0.0021 17.2 0.1 0.14 11.2 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4147) FAD_binding_2 PF00890.19 EER25931.1 - 0.0023 16.8 2.4 1.1 8.0 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain Amino_oxidase PF01593.19 EER25931.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EER25931.1 - 0.032 14.2 0.1 18 5.4 0.2 3.0 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EER25931.1 - 0.071 12.2 0.2 2.6 7.0 0.0 2.6 3 0 0 3 3 3 0 Thi4 family UPF0227 PF05728.7 EER25931.1 - 0.091 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GIDA PF01134.17 EER25931.1 - 0.11 11.3 9.3 0.73 8.6 0.3 4.2 4 1 1 5 5 5 0 Glucose inhibited division protein A HI0933_like PF03486.9 EER25931.1 - 0.29 9.5 5.6 0.75 8.1 0.8 3.2 3 1 1 4 4 4 0 HI0933-like protein Acetyltransf_1 PF00583.19 EER25932.1 - 3.3e-08 33.4 0.0 5.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER25932.1 - 2.1e-06 27.7 0.0 4.1e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER25932.1 - 0.0051 16.6 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER25932.1 - 0.0068 16.5 0.0 0.035 14.2 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF2935 PF11155.3 EER25933.1 - 0.0063 16.5 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) CMAS PF02353.15 EER25934.1 - 1.2e-59 201.6 0.0 1.5e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EER25934.1 - 2.5e-11 43.5 0.0 6.7e-11 42.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER25934.1 - 7.3e-07 29.5 0.0 1.3e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER25934.1 - 0.0028 18.2 0.0 0.011 16.2 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER25934.1 - 0.003 17.5 0.0 0.0078 16.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EER25934.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 EER25934.1 - 0.02 14.4 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EER25934.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EER25934.1 - 0.023 15.1 0.1 0.055 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EER25934.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EER25934.1 - 0.14 12.5 0.1 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EER25935.1 - 1.4e-93 313.5 0.0 1.7e-93 313.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER25935.1 - 2.6e-14 53.9 0.1 5.9e-14 52.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box PF00646.28 EER25936.1 - 0.0004 19.9 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain MCM PF00493.18 EER25937.1 - 1.3e-134 448.2 0.0 2.3e-134 447.3 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EER25937.1 - 7.3e-28 97.4 1.1 2.8e-27 95.5 0.7 2.1 1 1 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EER25937.1 - 6.2e-07 28.7 0.0 5.2e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EER25937.1 - 5.5e-06 26.1 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EER25937.1 - 0.038 13.5 0.0 0.15 11.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EER25937.1 - 0.056 13.8 0.0 0.33 11.3 0.0 2.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EER25937.1 - 0.066 13.1 2.6 11 5.9 0.3 3.2 2 1 0 3 3 3 0 AAA ATPase domain AAA PF00004.24 EER25937.1 - 0.067 13.4 1.9 5.8 7.1 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EER25938.1 - 2.4e-54 183.0 0.0 2.5e-43 147.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EER25938.1 - 1.7e-28 98.5 0.1 3.7e-28 97.4 0.1 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EER25938.1 - 3.9e-10 40.0 1.0 6e-05 23.1 0.0 3.5 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.9 EER25938.1 - 1.4e-06 28.3 0.0 0.082 12.8 0.0 2.8 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EER25938.1 - 2e-06 27.5 0.4 0.0013 18.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.1 EER25938.1 - 7.3e-06 25.9 0.0 0.089 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EER25938.1 - 9.7e-06 25.7 0.9 0.63 10.1 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EER25938.1 - 1.9e-05 25.4 0.0 0.18 12.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EER25938.1 - 6.7e-05 22.3 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EER25938.1 - 0.00011 21.8 0.0 0.23 11.2 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 EER25938.1 - 0.00024 21.4 0.6 0.19 12.0 0.1 3.1 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EER25938.1 - 0.00025 20.1 0.0 0.013 14.5 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EER25938.1 - 0.00039 20.3 0.0 0.38 10.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EER25938.1 - 0.0044 16.4 2.3 12 5.2 0.1 4.2 2 2 1 4 4 4 0 AAA domain TIP49 PF06068.8 EER25938.1 - 0.0058 15.4 0.0 1.5 7.4 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus RNA_helicase PF00910.17 EER25938.1 - 0.007 16.5 0.0 5.5 7.2 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EER25938.1 - 0.0089 15.1 0.0 1.7 7.6 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin T2SE PF00437.15 EER25938.1 - 0.011 14.6 0.0 0.044 12.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 EER25938.1 - 0.013 14.6 0.1 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.1 EER25938.1 - 0.024 14.6 0.0 8.8 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EER25938.1 - 0.025 14.2 0.0 0.44 10.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EER25938.1 - 0.038 13.4 0.0 0.49 9.8 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EER25938.1 - 0.052 13.8 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 EER25938.1 - 0.069 12.8 0.4 30 4.1 0.0 3.6 2 2 2 4 4 4 0 Archaeal ATPase KAP_NTPase PF07693.9 EER25938.1 - 0.13 11.2 0.1 0.71 8.8 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain Mg_chelatase PF01078.16 EER25938.1 - 0.13 11.4 0.2 0.85 8.7 0.0 2.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EER25938.1 - 0.32 9.9 0.0 12 4.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EER25938.1 - 0.45 9.9 1.2 10 5.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DAP3 PF10236.4 EER25939.1 - 6.6e-92 307.7 0.0 8.3e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RRS1 PF04939.7 EER25940.1 - 1.1e-57 194.1 1.9 1.3e-57 193.8 1.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 EER25941.1 - 1.1e-28 99.7 0.0 1.8e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 EER25942.1 - 8.9e-57 188.3 5.6 9.1e-13 47.5 0.1 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EER25942.1 - 2.5e-39 134.2 0.0 4.8e-12 46.2 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EER25942.1 - 2.7e-11 43.4 0.0 0.0001 22.2 0.0 3.3 2 1 1 3 3 3 3 Prenyltransferase-like MutS_V PF00488.16 EER25944.1 - 3.2e-87 291.8 0.0 5.1e-87 291.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EER25944.1 - 5.6e-35 120.9 0.5 1.2e-34 119.9 0.3 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EER25944.1 - 3.4e-29 101.1 0.0 8.3e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EER25944.1 - 4.6e-08 33.2 0.0 2.3e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EER25944.1 - 1.9e-05 24.7 0.0 0.00017 21.6 0.1 2.6 3 0 0 3 3 3 1 MutS family domain IV Ribosomal_S28e PF01200.13 EER25945.1 - 1.3e-32 111.3 1.1 1.4e-32 111.2 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e HisG PF01634.13 EER25946.1 - 1.2e-49 167.9 0.1 2.1e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EER25946.1 - 2.1e-28 98.0 1.1 3.2e-28 97.4 0.2 1.8 2 0 0 2 2 2 1 HisG, C-terminal domain DUF1697 PF08002.6 EER25946.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) DUF1949 PF09186.6 EER25947.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) PrpF PF04303.8 EER25948.1 - 4e-98 328.5 0.6 4.4e-98 328.4 0.4 1.0 1 0 0 1 1 1 1 PrpF protein Peptidase_C48 PF02902.14 EER25949.1 - 7.6e-15 55.1 0.0 3.6e-14 52.8 0.0 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RhoGEF PF00621.15 EER25950.1 - 1.8e-37 128.9 0.1 1.1e-36 126.3 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 EER25950.1 - 1.1e-13 51.2 1.0 1.1e-13 51.2 0.7 2.1 3 0 0 3 3 3 1 BAR domain Telomerase_RBD PF12009.3 EER25951.1 - 9.9e-42 142.0 0.0 2.4e-41 140.8 0.0 1.7 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EER25951.1 - 1.3e-12 47.5 0.0 5.9e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RabGAP-TBC PF00566.13 EER25952.1 - 2.4e-25 89.2 0.0 3.9e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cyclin PF08613.6 EER25953.1 - 8.7e-35 120.3 7.6 2.7e-22 79.8 0.1 3.1 3 1 0 3 3 3 2 Cyclin Mucin PF01456.12 EER25954.1 - 0.0067 16.2 10.4 0.0067 16.2 7.2 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein EXS PF03124.9 EER25955.1 - 6.2e-84 281.9 2.6 7.9e-84 281.6 1.8 1.1 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 EER25956.1 - 1.3e-43 149.0 4.3 1.6e-43 148.7 3.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EER25956.1 - 6.3e-11 41.9 9.9 1.1e-10 41.1 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EER25956.1 - 1.1e-10 40.9 7.5 1.9e-10 40.2 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER25956.1 - 1.7e-10 40.7 9.7 2.9e-10 40.0 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER25956.1 - 7.6e-10 38.3 5.6 1.2e-09 37.6 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER25956.1 - 4.1e-08 32.8 6.8 6.6e-08 32.1 4.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EER25956.1 - 4.2e-06 26.3 2.5 1.3e-05 24.7 1.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EER25956.1 - 1.4e-05 24.8 9.1 2.5e-05 24.0 6.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EER25956.1 - 2.6e-05 24.2 7.8 7.6e-05 22.7 5.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EER25956.1 - 0.0019 17.9 3.1 0.0036 17.0 2.1 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EER25956.1 - 0.0045 16.4 4.4 0.0087 15.5 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EER25956.1 - 0.0045 16.7 1.5 0.0093 15.7 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EER25956.1 - 0.11 12.0 8.5 0.23 11.0 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 EER25956.1 - 0.85 9.5 6.2 2.7 7.9 4.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 EER25956.1 - 1.2 9.0 7.7 5.2 7.0 5.4 2.0 1 1 0 1 1 1 0 IBR domain AA_permease PF00324.16 EER25957.1 - 7.7e-135 449.9 41.3 1.1e-134 449.3 28.6 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER25957.1 - 7.8e-33 113.6 42.8 1.1e-32 113.1 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EER25957.1 - 0.067 11.6 0.2 0.1 11.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) RhoGAP PF00620.22 EER25958.1 - 4.9e-15 55.4 0.0 1.3e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EER25958.1 - 3.4e-13 49.5 0.7 1e-12 48.0 0.0 2.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EER25958.1 - 2.4e-11 43.2 0.0 5.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) AAA_22 PF13401.1 EER25959.1 - 1.8e-15 57.2 0.0 3.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER25959.1 - 6.2e-15 55.6 0.6 4.8e-14 52.7 0.1 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA PF00004.24 EER25959.1 - 3.1e-13 50.0 0.0 5.7e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.6 EER25959.1 - 9.6e-07 28.4 0.0 2.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal AAA_5 PF07728.9 EER25959.1 - 0.00012 21.8 0.0 0.00037 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) PIF1 PF05970.9 EER25959.1 - 0.00082 18.4 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 EER25959.1 - 0.0025 17.5 0.0 0.0092 15.7 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_17 PF13207.1 EER25959.1 - 0.0028 18.4 0.0 0.0051 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EER25959.1 - 0.003 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 EER25959.1 - 0.0033 17.0 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EER25959.1 - 0.0081 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 EER25959.1 - 0.0082 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain T2SE PF00437.15 EER25959.1 - 0.0083 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_11 PF13086.1 EER25959.1 - 0.0092 15.5 0.0 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EER25959.1 - 0.0098 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EER25959.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EER25959.1 - 0.017 15.4 0.0 0.048 13.9 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 EER25959.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EER25959.1 - 0.018 14.9 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EER25959.1 - 0.028 14.7 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EER25959.1 - 0.029 13.4 0.0 0.082 11.9 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 EER25959.1 - 0.045 12.7 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EER25959.1 - 0.05 13.3 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase RNA12 PF10443.4 EER25959.1 - 0.081 11.4 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein Miro PF08477.8 EER25959.1 - 0.16 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Thioredoxin_7 PF13899.1 EER25960.1 - 1.1e-13 51.0 0.0 2.2e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 EER25960.1 - 2.4e-13 49.3 0.1 5.5e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EER25960.1 - 2.6e-07 30.6 0.0 3.2e-06 27.1 0.0 2.7 2 1 1 3 3 3 1 UBX domain Thioredoxin_2 PF13098.1 EER25960.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like domain Pkinase PF00069.20 EER25961.1 - 2.8e-69 233.1 0.0 4.5e-69 232.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25961.1 - 1.1e-50 172.2 0.0 1.6e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER25961.1 - 0.0076 15.2 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.20 EER25962.1 - 4.4e-54 183.3 0.0 6.5e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25962.1 - 1.2e-23 83.4 0.0 1.9e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EER25962.1 - 2.3e-17 62.8 0.0 4.4e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EER25962.1 - 1.5e-07 30.6 0.0 2.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EER25962.1 - 0.0027 16.5 0.2 0.0047 15.7 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase SPAM PF02090.10 EER25963.1 - 0.0018 18.2 0.5 1.2 9.1 0.4 3.1 3 0 0 3 3 3 2 Salmonella surface presentation of antigen gene type M protein ADH_N PF08240.7 EER25964.1 - 2.1e-25 88.5 1.9 4e-25 87.6 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER25964.1 - 4.9e-22 77.8 0.2 7.7e-22 77.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER25964.1 - 0.00063 20.6 0.2 0.0014 19.5 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.4 EER25964.1 - 0.31 10.2 5.8 0.96 8.6 4.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SWIM PF04434.12 EER25965.1 - 0.0033 16.8 0.2 0.0055 16.1 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger SET PF00856.23 EER25966.1 - 1.3e-07 32.0 0.0 0.00013 22.3 0.0 2.6 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 EER25966.1 - 1e-05 25.0 0.1 2.4e-05 23.9 0.1 1.6 1 0 0 1 1 1 1 TPR repeat SAP PF02037.22 EER25966.1 - 0.00065 19.1 1.5 0.0011 18.3 0.2 2.1 2 0 0 2 2 2 1 SAP domain TPR_9 PF13371.1 EER25966.1 - 0.017 14.9 0.0 0.053 13.3 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.1 EER25968.1 - 4.2e-14 52.0 16.8 1e-07 31.8 1.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EER25968.1 - 2.2e-09 37.1 29.7 0.0039 17.4 5.3 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER25968.1 - 4.2e-08 32.9 22.5 0.0076 16.5 4.6 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EER25968.1 - 0.005 16.7 13.6 0.079 12.8 0.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-CHCC PF10276.4 EER25968.1 - 0.014 15.2 5.0 1.4 8.8 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger domain zf-C2HC_2 PF13913.1 EER25968.1 - 0.031 13.9 1.0 0.031 13.9 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EER25968.1 - 0.041 13.9 11.0 0.086 12.9 4.7 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 EER25968.1 - 0.18 11.8 4.1 17 5.5 0.1 3.6 3 0 0 3 3 3 0 zinc-finger zf-C2H2_jaz PF12171.3 EER25968.1 - 0.22 11.6 15.6 0.69 10.1 1.9 3.6 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding DZR PF12773.2 EER25968.1 - 0.25 11.1 6.5 2.9 7.7 4.5 2.2 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EER25968.1 - 0.29 11.1 9.1 2.8 7.9 2.2 3.1 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EER25968.1 - 0.7 9.7 9.3 3.8 7.3 3.2 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CHY PF05495.7 EER25968.1 - 0.78 9.9 7.3 1.7 8.8 5.1 1.5 1 0 0 1 1 1 0 CHY zinc finger FYDLN_acid PF09538.5 EER25968.1 - 0.84 10.2 10.6 1.4 9.5 0.4 3.8 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) GAGA PF09237.6 EER25968.1 - 4 7.0 10.5 3 7.4 1.1 3.0 1 1 2 3 3 3 0 GAGA factor zf-C2H2_2 PF12756.2 EER25968.1 - 4.6 7.4 11.3 1.9 8.6 1.1 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zinc_ribbon_4 PF13717.1 EER25968.1 - 8.6 6.1 7.2 8 6.2 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EER25968.1 - 8.9 5.9 7.3 7.5 6.2 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain DUF3074 PF11274.3 EER25969.1 - 2.2e-30 105.6 0.0 3.1e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Stk19 PF10494.4 EER25970.1 - 1.6e-76 257.0 0.0 2e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Glyco_transf_20 PF00982.16 EER25971.1 - 3.6e-148 493.9 0.0 5.8e-105 351.4 0.0 2.1 1 1 1 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EER25971.1 - 3.2e-39 134.2 0.0 5.3e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EER25971.1 - 0.032 13.7 0.1 0.059 12.8 0.1 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain Peptidase_MA_2 PF13485.1 EER25971.1 - 0.081 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily 4HBT_3 PF13622.1 EER25972.1 - 9.7e-47 159.8 0.7 1.1e-46 159.6 0.5 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EER25973.1 - 0.00012 22.1 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily TIL PF01826.12 EER25975.1 - 1.8 8.7 10.8 0.37 10.9 4.7 1.9 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain PCI PF01399.22 EER25976.1 - 4e-13 49.6 0.1 1.2e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 PCI domain BSMAP PF12280.3 EER25976.1 - 0.053 13.4 0.1 9.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Brain specific membrane anchored protein Ribosomal_S14 PF00253.16 EER25977.1 - 3e-18 64.9 5.3 3.2e-18 64.8 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EER25977.1 - 0.043 13.5 0.5 0.059 13.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2318 PF10080.4 EER25977.1 - 0.047 13.4 0.2 0.05 13.3 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) A2L_zn_ribbon PF08792.5 EER25977.1 - 0.087 12.3 0.3 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain Prim_Zn_Ribbon PF08273.7 EER25977.1 - 1 9.4 3.8 6.1 7.0 0.3 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Toxin_17 PF08086.6 EER25977.1 - 1.1 9.3 4.8 0.75 9.8 0.5 2.0 1 1 1 2 2 2 0 Ergtoxin family ADK PF00406.17 EER25978.1 - 1.4e-40 138.6 0.0 3.8e-40 137.2 0.0 1.6 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EER25978.1 - 3.8e-10 40.1 0.0 5.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EER25978.1 - 3.7e-08 34.2 0.0 5.8e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER25978.1 - 8.4e-06 25.7 0.0 0.0028 17.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.12 EER25978.1 - 8.2e-05 22.0 0.0 0.0011 18.3 0.0 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_19 PF13245.1 EER25978.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain MARVEL PF01284.18 EER25979.1 - 0.0016 18.2 7.8 0.0016 18.2 5.4 1.8 1 1 0 2 2 2 1 Membrane-associating domain Claudin_2 PF13903.1 EER25979.1 - 0.024 14.3 2.6 0.044 13.4 1.4 1.5 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Tetraspannin PF00335.15 EER25979.1 - 0.033 13.4 8.7 0.056 12.7 6.0 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF202 PF02656.10 EER25979.1 - 2.8 8.2 6.4 16 5.7 2.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Cnd2 PF05786.9 EER25980.1 - 5.1e-241 802.1 0.0 6.2e-241 801.9 0.0 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 DUF4611 PF15387.1 EER25980.1 - 0.018 15.1 1.1 0.018 15.1 0.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Na_Ca_ex PF01699.19 EER25981.1 - 7e-46 155.3 41.5 1.5e-25 89.3 10.2 3.5 4 0 0 4 4 4 2 Sodium/calcium exchanger protein PDR_CDR PF06422.7 EER25981.1 - 0.02 14.5 0.4 21 4.8 0.0 3.6 4 0 0 4 4 4 0 CDR ABC transporter EF-hand_4 PF12763.2 EER25982.1 - 5.9e-24 83.7 0.0 6.4e-13 48.3 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EER25982.1 - 2.2e-09 36.6 0.6 6.1e-09 35.1 0.4 1.8 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.6 EER25982.1 - 0.00023 21.1 31.7 0.00023 21.1 21.9 7.4 5 2 1 6 6 6 3 Domain of unknown function (DUF1720) EF-hand_7 PF13499.1 EER25982.1 - 0.013 15.5 0.8 0.54 10.4 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.27 EER25982.1 - 0.1 11.9 0.0 20 4.7 0.0 2.5 2 0 0 2 2 2 0 EF hand RNA_pol_L_2 PF13656.1 EER25983.1 - 4.3e-25 86.9 0.0 5.7e-25 86.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EER25983.1 - 9.1e-14 50.3 0.0 1.2e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Rio2_N PF09202.6 EER25983.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Rio2, N-terminal NMO PF03060.10 EER25984.1 - 2e-43 148.8 1.0 1.5e-42 145.9 0.7 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.13 EER25984.1 - 3e-09 36.2 4.0 4.3e-09 35.6 2.8 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EER25984.1 - 1e-07 31.2 0.0 0.0014 17.5 1.1 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EER25984.1 - 5.4e-05 22.2 1.7 9.3e-05 21.5 1.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase PBP1_TM PF14812.1 EER25985.1 - 0.52 10.6 14.2 10 6.4 0.1 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GOLD_2 PF13897.1 EER25985.1 - 5.6 7.2 5.0 14 5.8 3.5 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking LRR_8 PF13855.1 EER25986.1 - 3.1e-07 30.0 6.3 0.088 12.5 0.2 4.3 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.2 EER25986.1 - 1e-06 28.2 1.7 0.26 10.9 0.4 5.6 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) TFIIF_alpha PF05793.7 EER25986.1 - 0.0068 14.8 8.8 0.0098 14.3 6.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TATR PF03430.8 EER25986.1 - 0.11 11.0 6.8 0.16 10.6 4.7 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator FYVE PF01363.16 EER25986.1 - 0.78 9.6 5.4 0.31 10.9 1.1 2.3 2 1 0 2 2 2 0 FYVE zinc finger DUF4407 PF14362.1 EER25986.1 - 1.1 8.1 5.5 1.7 7.5 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1675 PF07897.6 EER25986.1 - 1.5 8.5 8.2 2.4 7.9 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SNF2_N PF00176.18 EER25987.1 - 1.3e-63 214.5 0.1 2.4e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER25987.1 - 2.9e-12 46.2 0.0 9.8e-12 44.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER25987.1 - 1.7e-07 31.2 0.6 5.7e-07 29.5 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 EER25987.1 - 2.1e-07 30.4 7.8 2.1e-07 30.4 5.4 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER25987.1 - 3.3e-05 23.8 7.2 3.3e-05 23.8 5.0 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER25987.1 - 0.00013 21.7 7.5 0.00013 21.7 5.2 2.5 2 0 0 2 2 1 1 Ring finger domain DEAD PF00270.24 EER25987.1 - 0.0018 17.8 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 EER25987.1 - 0.0042 16.7 2.3 0.017 14.8 1.6 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EER25987.1 - 0.097 12.4 2.5 0.29 10.9 1.7 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PRP1_N PF06424.7 EER25987.1 - 0.26 11.5 6.1 0.87 9.9 0.3 2.6 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Zn_Tnp_IS91 PF14319.1 EER25987.1 - 0.75 9.3 15.7 0.024 14.1 1.9 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Pkinase PF00069.20 EER25989.1 - 1.8e-31 109.2 0.0 1.2e-30 106.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25989.1 - 7.5e-08 31.7 0.0 0.00082 18.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EER25990.1 - 7.2e-12 45.5 0.1 8.1e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER25990.1 - 3.3e-05 23.5 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EER25990.1 - 0.0027 17.0 0.0 0.0038 16.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family SBP_bac_3 PF00497.15 EER25990.1 - 0.0095 15.2 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 C2 PF00168.25 EER25991.1 - 2.1e-12 46.7 0.0 4.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain SR-25 PF10500.4 EER25991.1 - 8 5.8 12.1 0.053 12.9 1.9 2.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein ArfGap PF01412.13 EER25992.1 - 5.7e-35 119.6 0.1 5.7e-35 119.6 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EER25992.1 - 1.8e-12 47.4 0.1 6.7e-12 45.5 0.1 2.1 1 0 0 1 1 1 1 PH domain EMP24_GP25L PF01105.19 EER25992.1 - 0.015 14.9 3.2 0.19 11.4 1.6 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD CK2S PF15011.1 EER25992.1 - 0.029 14.1 0.6 5.7 6.7 0.1 2.4 2 0 0 2 2 2 0 Casein Kinase 2 substrate DASH_Dam1 PF08653.5 EER25992.1 - 0.48 10.2 0.0 0.48 10.2 0.0 2.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 PI3_PI4_kinase PF00454.22 EER25995.1 - 1.4e-35 122.8 0.1 1.1e-33 116.7 0.0 3.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EER25995.1 - 1.1e-21 76.8 0.1 2.7e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Mtr2 PF10429.4 EER25995.1 - 0.097 12.4 0.0 18 5.0 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 Pkinase PF00069.20 EER25996.1 - 5.2e-77 258.5 0.0 7e-77 258.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25996.1 - 1.1e-36 126.2 0.0 1.5e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EER25996.1 - 5.6e-17 61.6 0.2 1.3e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EER25996.1 - 1.2e-08 34.3 0.0 2.9e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EER25996.1 - 0.00016 21.5 0.2 0.00043 20.0 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EER25996.1 - 0.0012 17.9 0.2 0.0022 17.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EER25996.1 - 0.032 13.0 0.1 0.047 12.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase p450 PF00067.17 EER25997.1 - 2.3e-66 224.2 0.0 2.9e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3684 PF12449.3 EER25997.1 - 0.071 10.6 0.1 0.1 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) IGR PF09597.5 EER25998.1 - 1e-21 76.5 0.2 2.1e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 IGR protein motif Pkinase PF00069.20 EER25999.1 - 2.6e-61 207.0 0.0 3.1e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER25999.1 - 6.4e-32 110.6 0.0 1e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER25999.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EER25999.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Syja_N PF02383.13 EER26000.1 - 3.2e-81 272.5 0.0 4.3e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EER26000.1 - 9e-26 91.3 0.0 1.8e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EER26000.1 - 0.0012 18.4 0.0 0.0037 16.8 0.0 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase DUF2972 PF11186.3 EER26001.1 - 0.014 15.3 0.4 0.017 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Mlp PF03304.8 EER26001.1 - 0.048 13.6 0.4 0.065 13.2 0.2 1.2 1 0 0 1 1 1 0 Mlp lipoprotein family MRP-S26 PF14943.1 EER26001.1 - 0.13 11.7 3.4 0.15 11.5 2.4 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 CDC37_N PF03234.9 EER26001.1 - 0.14 12.4 2.9 0.12 12.7 0.6 1.7 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding Alb1 PF09135.6 EER26001.1 - 2.1 8.9 10.1 8.6 7.0 7.0 1.9 1 1 0 1 1 1 0 Alb1 SR-25 PF10500.4 EER26002.1 - 0.028 13.9 20.3 0.041 13.3 14.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hid1 PF12722.2 EER26002.1 - 2.6 5.6 6.7 2.9 5.4 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.7 EER26002.1 - 4.1 7.2 8.5 5.4 6.8 5.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DAGAT PF03982.8 EER26004.1 - 4.6e-91 304.5 0.0 5.9e-91 304.2 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EER26004.1 - 0.04 13.5 3.9 0.069 12.7 2.7 1.3 1 0 0 1 1 1 0 Rer1 family Glyco_transf_11 PF01531.11 EER26005.1 - 0.13 11.1 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 11 Kinesin PF00225.18 EER26006.1 - 2.6e-97 325.5 0.1 5.6e-97 324.4 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Adaptin_N PF01602.15 EER26007.1 - 1.8e-73 247.7 0.0 5.8e-73 245.9 0.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EER26007.1 - 1e-05 25.6 2.7 0.11 12.8 0.5 3.7 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EER26007.1 - 0.00035 20.4 1.4 4.5 7.6 0.1 4.2 4 0 0 4 4 4 2 HEAT repeat BLVR PF06375.6 EER26007.1 - 0.02 14.7 0.2 0.02 14.7 0.1 2.8 2 1 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) HEAT_EZ PF13513.1 EER26007.1 - 0.025 15.0 1.9 2.1 8.9 0.0 4.0 3 0 0 3 3 3 0 HEAT-like repeat BAGE PF08180.6 EER26007.1 - 0.026 14.2 0.2 0.056 13.2 0.2 1.6 1 0 0 1 1 1 0 B melanoma antigen family Cnd1 PF12717.2 EER26007.1 - 0.037 13.8 6.4 0.14 12.0 1.0 2.9 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TPR_16 PF13432.1 EER26008.1 - 1.6e-06 28.5 0.9 0.032 14.9 0.0 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EER26008.1 - 2.8e-06 26.8 4.1 3.8e-05 23.2 0.2 3.4 2 1 2 4 4 4 2 TPR repeat TPR_14 PF13428.1 EER26008.1 - 1.1e-05 25.6 4.6 0.031 14.8 0.1 4.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER26008.1 - 0.001 19.0 1.0 0.067 13.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EER26008.1 - 0.0022 17.8 1.4 0.22 11.5 0.1 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EER26008.1 - 0.0025 17.5 0.1 0.0025 17.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER26008.1 - 0.07 12.7 0.1 0.07 12.7 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Tcf25 PF04910.9 EER26008.1 - 0.13 11.1 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Transcriptional repressor TCF25 TPR_7 PF13176.1 EER26008.1 - 0.18 11.6 2.3 2 8.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat IF-2B PF01008.12 EER26009.1 - 1.9e-73 246.9 2.1 2.4e-73 246.5 1.4 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Flavi_NS1 PF00948.16 EER26009.1 - 0.023 13.1 0.0 0.03 12.7 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 SNN_transmemb PF09049.5 EER26010.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Stannin transmembrane APH PF01636.18 EER26011.1 - 3.8e-18 66.0 0.0 6.4e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER26011.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EER26011.1 - 0.0034 16.7 0.0 0.074 12.3 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EER26011.1 - 0.0062 15.6 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EER26011.1 - 0.096 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain EcKinase PF02958.15 EER26011.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase APH_6_hur PF04655.9 EER26011.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase_Tyr PF07714.12 EER26011.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase GAGA_bind PF06217.7 EER26013.1 - 9e-05 22.5 7.4 9e-05 22.5 5.1 1.1 1 0 0 1 1 1 1 GAGA binding protein-like family FLO_LFY PF01698.11 EER26013.1 - 0.0017 17.3 6.8 0.0019 17.1 4.7 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 EER26013.1 - 0.0037 17.0 6.8 0.0048 16.6 4.7 1.4 1 0 0 1 1 1 1 Peptidase family S49 N-terminal BLVR PF06375.6 EER26013.1 - 0.005 16.6 18.6 0.0069 16.2 12.9 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) U79_P34 PF03064.11 EER26013.1 - 0.013 15.0 10.6 0.017 14.6 7.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pox_Ag35 PF03286.9 EER26013.1 - 0.02 14.4 16.2 0.026 14.0 11.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Folate_carrier PF01770.13 EER26013.1 - 0.022 13.2 0.6 0.025 13.1 0.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier TAF1D PF15333.1 EER26013.1 - 0.027 14.2 11.8 0.034 13.9 8.2 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF1675 PF07897.6 EER26013.1 - 0.038 13.8 5.3 0.042 13.7 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) DUF1510 PF07423.6 EER26013.1 - 0.042 13.2 13.6 0.047 13.0 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Rtf2 PF04641.7 EER26013.1 - 0.089 11.9 16.0 0.11 11.6 11.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4337 PF14235.1 EER26013.1 - 0.13 12.0 2.7 0.15 11.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DDHD PF02862.12 EER26013.1 - 0.14 11.9 5.5 0.15 11.8 3.8 1.2 1 0 0 1 1 1 0 DDHD domain Serinc PF03348.10 EER26013.1 - 0.16 10.6 1.7 0.16 10.6 1.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) SspB PF04386.8 EER26013.1 - 0.2 11.2 6.1 0.27 10.8 4.2 1.2 1 0 0 1 1 1 0 Stringent starvation protein B Peroxin-13_N PF04088.8 EER26013.1 - 0.24 11.3 6.4 0.47 10.4 4.5 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Raftlin PF15250.1 EER26013.1 - 0.37 9.2 8.2 0.46 8.9 5.7 1.1 1 0 0 1 1 1 0 Raftlin RNA_polI_A34 PF08208.6 EER26013.1 - 0.41 10.2 23.5 0.54 9.9 16.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DUF2457 PF10446.4 EER26013.1 - 0.55 8.8 16.4 0.72 8.5 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1517 PF07466.6 EER26013.1 - 0.64 8.9 3.3 0.8 8.6 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Vfa1 PF08432.5 EER26013.1 - 0.64 10.0 19.6 0.93 9.4 13.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NARP1 PF12569.3 EER26013.1 - 0.72 8.5 20.1 0.92 8.1 13.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AIF_C PF14721.1 EER26013.1 - 2.4 8.4 7.2 3 8.0 5.0 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term MFMR PF07777.6 EER26013.1 - 2.6 7.9 5.7 3.4 7.5 4.0 1.3 1 0 0 1 1 1 0 G-box binding protein MFMR APC_CDC26 PF10471.4 EER26013.1 - 2.9 8.6 12.3 5.6 7.7 8.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 OAD_gamma PF04277.8 EER26013.1 - 3 8.2 8.3 7.4 7.0 5.8 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Paramyxo_ncap PF00973.14 EER26013.1 - 3.2 6.3 6.5 3.7 6.1 4.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NPR3 PF03666.8 EER26013.1 - 3.5 6.0 16.4 4.9 5.5 11.3 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1980 PF09323.5 EER26013.1 - 3.9 7.1 8.2 3.9 7.1 5.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Cellulose_synt PF03552.9 EER26013.1 - 4.3 5.5 8.4 4.9 5.3 5.8 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF1168 PF06658.7 EER26013.1 - 5.2 6.5 28.9 7.4 6.0 20.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Gti1_Pac2 PF09729.4 EER26013.1 - 8.3 6.2 11.9 12 5.6 8.3 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DEAD PF00270.24 EER26014.1 - 3e-44 150.5 0.0 4.9e-43 146.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER26014.1 - 4.7e-25 87.2 0.0 1.2e-24 85.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER26014.1 - 0.0002 21.2 0.0 0.0005 19.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF677 PF05055.7 EER26014.1 - 0.034 12.8 0.0 0.051 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF1253 PF06862.7 EER26014.1 - 0.036 12.4 0.1 3.1 6.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) Rft-1 PF04506.8 EER26015.1 - 2.6e-74 250.5 6.3 3.5e-74 250.1 4.4 1.1 1 0 0 1 1 1 1 Rft protein Peptidase_U4 PF03419.8 EER26015.1 - 4.7 6.2 7.3 2.4 7.1 0.0 3.4 3 1 1 4 4 4 0 Sporulation factor SpoIIGA Rep_fac-A_C PF08646.5 EER26016.1 - 9.7e-47 158.3 2.1 3e-44 150.2 0.7 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EER26016.1 - 9.1e-23 79.9 0.0 4.2e-22 77.8 0.0 2.1 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EER26016.1 - 1.4e-12 47.2 0.0 1.7e-09 37.3 0.0 3.7 3 1 1 4 4 4 1 OB-fold nucleic acid binding domain zf-C5HC2 PF02928.11 EER26016.1 - 0.22 11.5 2.2 0.5 10.4 1.5 1.5 1 0 0 1 1 1 0 C5HC2 zinc finger UDG PF03167.14 EER26017.1 - 6.4e-26 90.6 0.1 9e-26 90.1 0.1 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily DUF2673 PF10880.3 EER26017.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2673) DNA_pol_E_B PF04042.11 EER26018.1 - 1.2e-46 158.6 0.0 1.7e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Med14 PF08638.6 EER26019.1 - 1.3e-69 233.3 0.4 7.4e-69 230.9 0.0 2.3 2 0 0 2 2 2 1 Mediator complex subunit MED14 DWNN PF08783.6 EER26020.1 - 5.1e-33 112.8 0.1 9.2e-33 112.0 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EER26020.1 - 5e-06 25.8 7.1 1.4e-05 24.4 4.9 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EER26020.1 - 0.0051 16.6 1.3 0.012 15.5 0.9 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-Nse PF11789.3 EER26020.1 - 0.17 11.4 3.6 0.39 10.2 2.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EER26020.1 - 5.6 6.7 13.1 0.35 10.6 4.8 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Oxidored_q6 PF01058.17 EER26021.1 - 3.7e-22 78.3 0.0 6e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF3158 PF11358.3 EER26022.1 - 0.092 12.2 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3158) NifU_N PF01592.11 EER26023.1 - 1.5e-49 167.1 0.0 2.2e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Aldedh PF00171.17 EER26024.1 - 3e-11 42.3 1.6 2.2e-08 32.8 0.4 2.9 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L18e PF00828.14 EER26025.1 - 1.9e-27 96.2 0.1 3.4e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Sedlin_N PF04628.8 EER26026.1 - 7.2e-23 80.8 0.0 8.3e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EER26026.1 - 0.09 12.4 0.0 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Sybindin-like family RRM_1 PF00076.17 EER26027.1 - 8.5e-12 44.5 0.0 1.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER26027.1 - 1.7e-07 30.9 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER26027.1 - 2.7e-07 30.4 0.0 4.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER26027.1 - 0.0039 16.9 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EER26027.1 - 7 4.9 14.6 9 4.6 10.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mito_carr PF00153.22 EER26028.1 - 1.7e-77 255.2 0.7 1.3e-25 88.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PXA PF02194.10 EER26029.1 - 1.5e-33 115.9 0.2 2.3e-32 112.0 0.0 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EER26029.1 - 1.3e-17 63.9 0.0 5.9e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EER26029.1 - 7.7e-12 45.0 0.0 3.1e-11 43.0 0.0 2.1 2 0 0 2 2 2 1 PX domain PRELI PF04707.9 EER26031.1 - 1.2e-44 151.6 0.1 1.4e-44 151.3 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family GATase_3 PF07685.9 EER26031.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CTP_transf_2 PF01467.21 EER26032.1 - 3e-18 66.3 0.0 1.3e-14 54.5 0.0 2.9 3 1 0 3 3 3 2 Cytidylyltransferase AvrRpt-cleavage PF05627.6 EER26032.1 - 0.13 11.3 0.4 0.25 10.3 0.3 1.4 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr Glutaredoxin PF00462.19 EER26033.1 - 2.6e-16 59.3 0.0 5.2e-16 58.3 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin Flavoprotein PF02441.14 EER26034.1 - 4.5e-39 133.0 0.1 5.6e-39 132.7 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein UbiA PF01040.13 EER26035.1 - 1.8e-30 106.0 22.9 2.5e-30 105.5 15.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family JmjC PF02373.17 EER26036.1 - 3.6e-08 33.6 2.6 2.2e-07 31.1 0.5 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EER26036.1 - 6.5e-08 32.6 7.1 6.5e-08 32.6 4.9 2.3 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EER26036.1 - 0.0064 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Med10 PF09748.4 EER26036.1 - 0.052 13.3 0.3 0.32 10.8 0.1 2.2 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF805 PF05656.9 EER26037.1 - 0.47 10.3 2.8 23 4.8 0.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF805) Coa1 PF08695.5 EER26038.1 - 1.6e-35 121.1 0.0 3e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2207 PF09972.4 EER26038.1 - 1.2 7.6 7.5 0.83 8.1 4.7 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_L3 PF00297.17 EER26039.1 - 8e-38 130.3 2.0 1.2e-37 129.7 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L3 DUF1279 PF06916.8 EER26040.1 - 7.4e-26 90.2 0.0 1.2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ank_2 PF12796.2 EER26041.1 - 9.3e-37 125.2 0.7 2.4e-12 47.0 0.0 4.2 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER26041.1 - 6.5e-33 112.5 3.8 3.2e-14 52.9 0.0 6.3 6 1 1 7 7 7 4 Ankyrin repeats (many copies) SPX PF03105.14 EER26041.1 - 3.3e-31 109.1 4.3 4.1e-28 98.9 3.0 2.2 1 1 0 1 1 1 1 SPX domain Ank PF00023.25 EER26041.1 - 6.6e-27 91.9 6.4 0.00014 21.4 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_3 PF13606.1 EER26041.1 - 2.8e-21 73.4 8.6 8.1e-05 22.5 0.0 8.3 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 EER26041.1 - 1.3e-15 56.9 7.8 1.7e-05 24.8 0.0 6.4 2 1 5 7 7 7 5 Ankyrin repeats (many copies) GDPD PF03009.12 EER26041.1 - 1.7e-13 50.7 0.0 7.1e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF4631 PF15450.1 EER26041.1 - 0.065 11.5 1.2 0.097 10.9 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4631) SKG6 PF08693.5 EER26042.1 - 2.1e-08 33.3 6.7 3.8e-08 32.4 4.7 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EER26042.1 - 7.9e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4126 PF13548.1 EER26042.1 - 0.021 14.2 0.7 0.032 13.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) EphA2_TM PF14575.1 EER26042.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M56 PF05569.6 EER26042.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 EzrA PF06160.7 EER26042.1 - 0.26 9.4 0.0 0.34 9.0 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA MFS_1 PF07690.11 EER26044.1 - 1.2e-38 132.7 41.0 1.2e-38 132.7 28.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER26045.1 - 2.7e-104 349.2 14.4 2e-79 267.3 3.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EER26045.1 - 2.3e-24 85.7 36.3 3.1e-13 49.1 5.7 3.2 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EER26045.1 - 0.00021 19.6 1.3 0.00021 19.6 0.9 2.1 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 EER26045.1 - 0.061 11.8 7.5 0.16 10.4 0.0 2.7 3 0 0 3 3 3 0 LacY proton/sugar symporter ABC_tran PF00005.22 EER26046.1 - 2e-47 160.9 0.3 1.3e-22 80.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EER26046.1 - 1.5e-20 72.7 5.5 1.5e-20 72.7 3.8 3.0 4 0 0 4 4 2 1 ABC transporter AAA_21 PF13304.1 EER26046.1 - 3.9e-16 59.8 5.0 0.00033 20.7 0.0 4.7 4 1 0 4 4 3 3 AAA domain SMC_N PF02463.14 EER26046.1 - 7.4e-11 41.7 0.2 0.013 14.7 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EER26046.1 - 6.7e-10 39.8 1.8 0.001 19.8 0.0 3.4 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EER26046.1 - 5.7e-07 29.4 0.0 0.027 14.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EER26046.1 - 1.1e-06 28.7 1.5 0.0012 18.8 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EER26046.1 - 2.3e-06 26.9 0.1 0.03 13.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EER26046.1 - 5.7e-06 25.7 0.2 0.068 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EER26046.1 - 5.9e-06 26.7 13.6 0.019 15.2 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA_15 PF13175.1 EER26046.1 - 6.2e-06 25.5 7.5 0.5 9.3 0.1 4.8 4 2 1 5 5 5 3 AAA ATPase domain AAA_18 PF13238.1 EER26046.1 - 8.9e-06 26.0 3.2 0.2 11.9 0.0 3.9 5 0 0 5 5 4 2 AAA domain AAA_22 PF13401.1 EER26046.1 - 1.1e-05 25.5 0.0 0.16 12.1 0.0 3.0 3 1 0 3 3 2 2 AAA domain Miro PF08477.8 EER26046.1 - 1.9e-05 25.1 0.0 0.083 13.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 EER26046.1 - 6.1e-05 22.9 1.6 0.14 12.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 EER26046.1 - 0.0002 21.0 0.1 0.61 9.7 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EER26046.1 - 0.0002 21.3 2.1 0.23 11.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.7 EER26046.1 - 0.00044 19.9 0.0 0.58 9.7 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EER26046.1 - 0.00094 19.3 0.0 0.86 9.8 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EER26046.1 - 0.0011 18.8 4.8 0.87 9.3 0.0 3.9 4 0 0 4 4 3 1 Dynamin family ArgK PF03308.11 EER26046.1 - 0.0016 17.2 1.5 0.89 8.2 0.0 2.7 3 0 0 3 3 3 2 ArgK protein Zeta_toxin PF06414.7 EER26046.1 - 0.0025 16.9 0.9 0.75 8.8 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_14 PF13173.1 EER26046.1 - 0.0054 16.6 0.0 6.7 6.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 EER26046.1 - 0.0076 16.4 0.0 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_10 PF12846.2 EER26046.1 - 0.01 15.3 1.7 3.2 7.1 0.0 3.1 3 1 0 3 3 3 0 AAA-like domain SbcCD_C PF13558.1 EER26046.1 - 0.011 15.6 0.1 5.4 6.9 0.1 3.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EER26046.1 - 0.012 15.1 0.0 0.69 9.3 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EER26046.1 - 0.014 15.1 0.1 2.5 7.7 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EER26046.1 - 0.015 14.8 0.0 4.5 6.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EER26046.1 - 0.02 14.3 0.6 5.4 6.3 0.1 2.8 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EER26046.1 - 0.026 13.3 0.0 4 6.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 EER26046.1 - 0.028 13.8 0.4 2.7 7.4 0.3 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EER26046.1 - 0.033 13.9 0.5 7.4 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EER26046.1 - 0.038 13.4 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EER26046.1 - 0.069 12.5 0.1 9.9 5.5 0.0 2.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF3824 PF12868.2 EER26046.1 - 0.78 10.6 5.2 0.22 12.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) WD40 PF00400.27 EER26048.1 - 4.4e-49 162.6 28.5 9.3e-13 47.5 1.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EER26048.1 - 3.9e-05 23.4 17.0 0.01 15.5 1.5 4.4 2 2 3 5 5 5 2 Transcription factor IIIC subunit delta N-term YmzC PF14157.1 EER26048.1 - 0.043 13.6 0.0 7.1 6.5 0.0 3.4 5 0 0 5 5 5 0 YmzC-like protein SNF5 PF04855.7 EER26051.1 - 1.2e-69 234.5 0.0 1.7e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EER26051.1 - 0.046 13.0 3.5 0.035 13.4 0.9 2.1 2 0 0 2 2 2 0 GATA zinc finger Glug PF07581.7 EER26051.1 - 0.048 13.8 11.9 0.12 12.6 0.9 2.4 2 0 0 2 2 2 0 The GLUG motif Androgen_recep PF02166.11 EER26052.1 - 0.058 12.2 0.5 0.093 11.5 0.3 1.3 1 0 0 1 1 1 0 Androgen receptor AA_permease PF00324.16 EER26053.1 - 1.7e-96 323.4 29.7 2e-96 323.2 20.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER26053.1 - 9.3e-22 77.1 29.2 1.2e-21 76.7 20.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EER26053.1 - 0.018 14.8 4.5 0.018 14.8 3.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) DUF4131 PF13567.1 EER26053.1 - 8.5 5.7 12.0 0.72 9.2 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) Fungal_trans PF04082.13 EER26054.1 - 1.3e-19 70.1 0.0 2.4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26054.1 - 1.4e-07 31.3 10.5 2.3e-07 30.5 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF948 PF06103.6 EER26054.1 - 0.14 11.9 1.2 2.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Cupin_8 PF13621.1 EER26055.1 - 7.1e-23 81.3 0.0 1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EER26055.1 - 0.0029 17.8 0.0 0.0073 16.5 0.0 1.7 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EER26055.1 - 0.093 12.2 0.0 0.28 10.7 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.7 EER26055.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.4 2 0 0 2 2 2 0 Cupin superfamily protein CK_II_beta PF01214.13 EER26056.1 - 1.4e-77 259.4 0.0 2.6e-77 258.5 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EER26056.1 - 0.35 11.4 12.4 0.2 12.3 5.9 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal ATP-synt_E PF05680.7 EER26056.1 - 0.44 10.5 1.8 2.3 8.1 0.1 2.6 2 1 1 3 3 3 0 ATP synthase E chain Nucleoplasmin PF03066.10 EER26056.1 - 2.5 7.6 6.1 3.9 6.9 4.3 1.3 1 0 0 1 1 1 0 Nucleoplasmin bZIP_1 PF00170.16 EER26057.1 - 7.4e-05 22.6 8.0 0.00013 21.8 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EER26057.1 - 0.00091 19.0 8.2 0.0018 18.0 5.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EER26057.1 - 0.0015 18.7 2.3 0.0029 17.8 1.6 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Aminotran_4 PF01063.14 EER26058.1 - 2.1e-32 112.4 0.0 7.4e-32 110.6 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class IV Pkinase PF00069.20 EER26059.1 - 8.1e-16 57.9 0.0 1.8e-15 56.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26059.1 - 1.5e-08 34.0 0.0 5e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.4 EER26059.1 - 0.048 13.5 0.3 0.46 10.3 0.1 2.2 2 0 0 2 2 2 0 Parkin co-regulated protein Peptidase_M49 PF03571.10 EER26060.1 - 1.8e-233 775.6 0.0 2.2e-233 775.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 DUF3810 PF12725.2 EER26060.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Cyt-b5 PF00173.23 EER26061.1 - 3.4e-10 39.5 0.0 4.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 EER26062.1 - 9.8e-61 201.3 0.0 3.5e-19 68.1 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER26062.1 - 3.4e-43 145.4 0.0 1.5e-13 50.4 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER26062.1 - 1.8e-22 78.9 0.0 2.2e-08 33.8 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad10 PF03834.9 EER26063.1 - 1.7e-29 101.3 0.0 2.7e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EER26063.1 - 0.00049 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EER26063.1 - 0.0063 16.1 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EER26063.1 - 0.06 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fungal_trans_2 PF11951.3 EER26064.1 - 7.8e-12 44.4 0.0 4.9e-11 41.8 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Lyase_1 PF00206.15 EER26065.1 - 2.5e-20 72.9 0.0 4.8e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EER26065.1 - 5.4e-17 61.5 0.4 2.2e-16 59.6 0.0 2.3 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Fungal_trans PF04082.13 EER26066.1 - 3.4e-19 68.7 1.1 7.1e-19 67.6 0.8 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EER26066.1 - 0.0027 16.3 0.2 0.028 13.0 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain CHD5 PF04420.9 EER26067.1 - 2.8e-59 199.3 1.2 3.5e-59 199.0 0.8 1.1 1 0 0 1 1 1 1 CHD5-like protein Chloroplast_duf PF14476.1 EER26067.1 - 0.08 11.7 0.3 0.12 11.1 0.2 1.3 1 0 0 1 1 1 0 Petal formation-expressed DUF904 PF06005.7 EER26067.1 - 0.13 12.5 2.5 0.22 11.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF3752 PF12572.3 EER26067.1 - 0.64 10.1 7.1 1.1 9.4 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) PPTA PF01239.17 EER26068.1 - 0.014 14.6 7.4 0.17 11.2 0.4 3.7 5 0 0 5 5 5 0 Protein prenyltransferase alpha subunit repeat 4F5 PF04419.9 EER26069.1 - 1.8e-10 41.4 13.2 1.8e-10 41.4 9.2 2.4 2 1 0 2 2 2 1 4F5 protein family Seryl_tRNA_N PF02403.17 EER26069.1 - 4.9 7.2 9.4 6 6.9 6.5 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1423 PF07227.6 EER26069.1 - 5.8 5.4 8.5 6.2 5.3 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Neurensin PF14927.1 EER26070.1 - 0.0002 20.7 0.3 0.0002 20.7 0.2 2.5 1 1 1 2 2 2 1 Neurensin PIRT PF15099.1 EER26070.1 - 0.065 12.4 2.2 0.15 11.2 1.5 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family DUF3093 PF11292.3 EER26070.1 - 7.2 6.4 7.5 0.94 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) AA_permease_2 PF13520.1 EER26072.1 - 2.7e-49 167.8 45.5 3.7e-49 167.4 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER26072.1 - 2.3e-29 102.0 39.2 4.4e-29 101.1 27.2 1.3 1 1 0 1 1 1 1 Amino acid permease TRAM_LAG1_CLN8 PF03798.11 EER26074.1 - 2.5e-43 147.9 24.2 4.1e-43 147.2 16.8 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EER26074.1 - 1.1e-16 60.0 0.1 3.3e-16 58.5 0.1 1.9 1 0 0 1 1 1 1 TRAM1-like protein RRM_1 PF00076.17 EER26075.1 - 2.4e-14 52.6 0.0 6.5e-14 51.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER26075.1 - 2.1e-10 40.4 0.0 4.6e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER26075.1 - 7.2e-08 32.1 0.1 1.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER26075.1 - 0.043 13.5 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SMN PF06003.7 EER26076.1 - 2.8e-06 26.6 4.7 6.3e-05 22.2 0.7 2.3 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Thiolase_C PF02803.13 EER26078.1 - 1.1e-10 40.9 0.2 8.2e-10 38.1 0.2 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EER26078.1 - 1.2e-07 31.2 0.2 1e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EER26078.1 - 3.7e-05 22.8 0.3 0.0001 21.3 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EER26078.1 - 0.0062 16.0 0.5 0.011 15.2 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EER26078.1 - 0.018 13.5 0.1 0.038 12.4 0.0 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) DUF3208 PF11482.3 EER26078.1 - 0.043 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3208) Mito_carr PF00153.22 EER26079.1 - 6.5e-41 137.9 6.9 4.4e-16 58.3 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein BRO1 PF03097.13 EER26080.1 - 5.1e-111 371.0 0.4 1.2e-110 369.8 0.0 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EER26080.1 - 3.9e-85 285.4 16.6 8.1e-85 284.3 11.5 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV zf-C4H2 PF10146.4 EER26080.1 - 0.0054 16.7 6.6 0.0054 16.7 4.5 3.1 2 1 1 3 3 3 1 Zinc finger-containing protein bZIP_2 PF07716.10 EER26081.1 - 6.7e-13 48.2 13.5 1.6e-12 47.0 9.3 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EER26081.1 - 8.9e-07 28.7 11.9 1.6e-06 27.9 8.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EER26081.1 - 0.077 12.9 0.4 0.16 11.9 0.3 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family Phlebovirus_NSM PF07246.6 EER26081.1 - 0.12 11.5 2.7 0.2 10.8 1.8 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M CENP-N PF05238.8 EER26082.1 - 6.6e-113 377.7 0.0 8.7e-113 377.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF974 PF06159.8 EER26083.1 - 1.7e-70 237.3 0.0 2e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) DENN PF02141.16 EER26084.1 - 2e-58 197.1 0.2 3.7e-58 196.3 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EER26084.1 - 6.5e-20 70.9 0.3 1.3e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EER26084.1 - 4e-18 65.1 0.0 9e-18 64.0 0.0 1.7 1 0 0 1 1 1 1 uDENN domain C1_2 PF03107.11 EER26084.1 - 0.00027 20.9 4.3 0.00055 19.9 3.0 1.5 1 0 0 1 1 1 1 C1 domain C1_3 PF07649.7 EER26084.1 - 0.0046 16.9 3.8 0.0046 16.9 2.6 1.9 2 0 0 2 2 2 1 C1-like domain C1_1 PF00130.17 EER26084.1 - 0.0056 16.3 10.2 0.011 15.5 7.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EER26084.1 - 0.13 11.9 7.8 0.095 12.4 3.9 1.9 1 1 1 2 2 2 0 PHD-finger PHD_2 PF13831.1 EER26084.1 - 0.83 9.0 4.2 0.36 10.1 0.4 2.1 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.1 EER26084.1 - 1.4 8.7 7.0 2.5 7.8 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HIT PF04438.11 EER26084.1 - 5 6.8 6.5 11 5.7 4.5 1.6 1 1 0 1 1 1 0 HIT zinc finger TctB PF07331.6 EER26085.1 - 0.019 14.6 1.4 0.019 14.6 0.3 1.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family RasGEF PF00617.14 EER26086.1 - 6.6e-57 192.2 0.3 1.2e-56 191.4 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EER26086.1 - 1.1e-17 64.0 0.0 5.2e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 EER26086.1 - 1.4e-05 24.5 0.0 3.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EER26086.1 - 0.00015 21.1 0.0 0.00053 19.3 0.0 2.0 2 0 0 2 2 2 1 SH3 domain Pyr_redox_3 PF13738.1 EER26087.1 - 5.6e-19 69.0 0.0 2e-18 67.1 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER26087.1 - 8.1e-11 40.8 0.4 1.5e-09 36.5 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EER26087.1 - 1.9e-07 31.0 0.0 5.2e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EER26087.1 - 4.3e-06 25.8 0.0 0.0024 16.8 0.0 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EER26087.1 - 0.0012 17.8 0.0 0.17 10.7 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EER26087.1 - 0.014 15.2 0.0 0.29 10.9 0.0 2.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER26087.1 - 0.03 13.4 0.0 0.39 9.7 0.0 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 EER26087.1 - 0.033 13.9 0.8 0.14 11.9 0.0 2.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EER26087.1 - 0.043 13.9 0.0 43 4.1 0.0 3.2 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Malic_M PF03949.10 EER26087.1 - 0.089 12.3 0.0 4.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 EER26087.1 - 0.12 12.7 0.1 1.1 9.7 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Cut8_C PF08559.5 EER26089.1 - 9.4e-52 174.6 0.0 1.2e-51 174.2 0.0 1.1 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EER26089.1 - 6.6e-13 48.2 0.1 1.6e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EER26089.1 - 1.2e-10 41.2 4.5 2.4e-10 40.2 3.1 1.5 1 0 0 1 1 1 1 Cut8 proteasome-binding domain rRNA_proc-arch PF13234.1 EER26090.1 - 5.8e-96 320.7 0.1 9.8e-96 320.0 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EER26090.1 - 4.5e-64 214.9 1.8 4.5e-64 214.9 1.3 1.8 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EER26090.1 - 1.7e-21 76.4 0.0 3.9e-21 75.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER26090.1 - 8e-07 28.8 0.0 1.9e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER26090.1 - 0.01 15.7 0.0 0.089 12.6 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EER26090.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain COX7C PF02935.11 EER26091.1 - 4.3e-14 52.0 2.5 5e-14 51.8 1.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc IKI3 PF04762.7 EER26092.1 - 0 1092.9 0.0 0 1092.5 0.0 1.1 1 0 0 1 1 1 1 IKI3 family GHMP_kinases_N PF00288.21 EER26093.1 - 4.5e-11 42.6 0.6 1e-10 41.5 0.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Cyto_heme_lyase PF01265.12 EER26094.1 - 2.2e-81 273.2 0.0 2.4e-81 273.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Tmemb_cc2 PF10267.4 EER26094.1 - 0.52 8.8 4.3 0.69 8.4 3.0 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Syntaxin_2 PF14523.1 EER26095.1 - 1.8e-25 88.9 2.2 1.8e-25 88.9 1.5 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EER26095.1 - 7.9e-18 63.9 3.6 8.6e-18 63.7 1.3 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EER26095.1 - 0.00038 20.5 0.3 0.00038 20.5 0.2 2.9 1 1 1 2 2 2 1 Syntaxin DUF883 PF05957.8 EER26095.1 - 0.0047 17.3 13.5 0.26 11.6 0.0 3.2 3 0 0 3 3 3 2 Bacterial protein of unknown function (DUF883) T2SF PF00482.18 EER26095.1 - 0.015 15.2 1.1 0.086 12.7 0.7 2.3 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Synaptobrevin PF00957.16 EER26095.1 - 0.023 14.2 0.1 0.023 14.2 0.1 2.1 2 0 0 2 2 2 0 Synaptobrevin Phasin_2 PF09361.5 EER26095.1 - 0.025 14.5 4.2 0.053 13.5 2.9 1.5 1 0 0 1 1 1 0 Phasin protein MCPsignal PF00015.16 EER26095.1 - 0.085 12.3 6.2 0.65 9.5 2.5 2.2 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain EspB PF05802.6 EER26095.1 - 0.18 10.6 5.2 3.1 6.6 0.3 2.2 2 0 0 2 2 2 0 Enterobacterial EspB protein Ndc1_Nup PF09531.5 EER26096.1 - 6.6e-152 507.0 0.1 7.5e-152 506.8 0.1 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF543 PF04418.7 EER26096.1 - 0.067 13.1 0.1 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) NUDIX PF00293.23 EER26097.1 - 3.8e-12 46.0 0.1 1.4e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 NUDIX domain DSPc PF00782.15 EER26098.1 - 2.1e-25 88.8 0.0 3e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EER26098.1 - 0.0036 16.6 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EER26098.1 - 0.034 14.4 0.1 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 EER26098.1 - 0.037 12.9 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase IBR PF01485.16 EER26098.1 - 2.4 8.0 4.9 3.1 7.7 0.2 2.5 2 1 0 2 2 2 0 IBR domain zf-C2H2_4 PF13894.1 EER26099.1 - 6.3e-06 26.1 14.1 0.0017 18.5 1.8 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EER26099.1 - 0.00011 22.1 11.7 0.0003 20.8 3.0 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EER26099.1 - 0.0006 19.9 7.4 0.0008 19.5 0.3 3.2 2 1 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 EER26099.1 - 0.0027 17.9 2.3 0.0027 17.9 1.6 4.1 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-met PF12874.2 EER26099.1 - 0.02 15.1 1.3 0.02 15.1 0.9 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DZR PF12773.2 EER26099.1 - 0.64 9.8 7.9 0.3 10.9 0.1 2.7 2 0 0 2 2 2 0 Double zinc ribbon zf-C2H2_6 PF13912.1 EER26099.1 - 0.79 9.7 7.0 6.6 6.7 1.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-FCS PF06467.9 EER26099.1 - 0.86 9.3 9.7 1.1 8.9 0.3 3.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif Vfa1 PF08432.5 EER26100.1 - 5.7e-64 215.4 15.5 6.4e-64 215.3 10.7 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF2252 PF10009.4 EER26100.1 - 0.01 14.7 3.1 0.01 14.7 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) DUF2347 PF09804.4 EER26100.1 - 0.019 14.2 1.3 0.026 13.8 0.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) MIP-T3 PF10243.4 EER26100.1 - 0.029 12.8 24.5 0.033 12.6 17.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 EER26100.1 - 0.037 13.9 15.6 0.051 13.4 10.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ycf1 PF05758.7 EER26100.1 - 0.042 11.5 13.3 0.049 11.3 9.2 1.0 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 EER26100.1 - 0.081 12.8 10.7 0.11 12.4 7.4 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2201_N PF13203.1 EER26100.1 - 0.096 11.8 5.0 0.12 11.5 3.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain RNA_polI_A34 PF08208.6 EER26100.1 - 0.1 12.2 28.6 0.14 11.7 19.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Raftlin PF15250.1 EER26100.1 - 0.12 10.8 6.3 0.15 10.5 4.3 1.1 1 0 0 1 1 1 0 Raftlin Caldesmon PF02029.10 EER26100.1 - 0.13 10.6 27.4 0.2 10.0 19.0 1.2 1 0 0 1 1 1 0 Caldesmon Spore_coat_CotO PF14153.1 EER26100.1 - 0.19 11.1 19.1 0.26 10.7 13.2 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Sec62 PF03839.11 EER26100.1 - 0.34 10.2 17.0 0.52 9.6 11.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.8 EER26100.1 - 0.48 8.8 11.9 0.65 8.4 8.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1510 PF07423.6 EER26100.1 - 0.5 9.6 22.6 0.67 9.2 15.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EER26100.1 - 0.59 8.1 16.6 0.69 7.8 11.5 1.0 1 0 0 1 1 1 0 CDC45-like protein APG6 PF04111.7 EER26100.1 - 0.8 8.6 12.0 0.93 8.4 8.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_11 PF13086.1 EER26100.1 - 1.4 8.4 6.1 1.9 7.9 4.2 1.2 1 0 0 1 1 1 0 AAA domain Pox_Ag35 PF03286.9 EER26100.1 - 1.6 8.2 18.6 2.3 7.7 12.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Spc24 PF08286.6 EER26100.1 - 1.7 8.3 12.1 13 5.5 9.2 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 GCD14 PF08704.5 EER26100.1 - 2.8 7.3 5.7 4.8 6.5 4.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Borrelia_P83 PF05262.6 EER26100.1 - 3.1 5.9 17.1 3.4 5.8 11.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein UPF0560 PF10577.4 EER26100.1 - 3.2 5.8 8.6 3.5 5.7 6.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4220 PF13968.1 EER26100.1 - 3.9 6.4 4.7 4.5 6.2 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) HSP70 PF00012.15 EER26100.1 - 4.2 5.1 14.1 4.6 5.0 9.8 1.0 1 0 0 1 1 1 0 Hsp70 protein Neur_chan_memb PF02932.11 EER26100.1 - 4.4 7.1 6.9 5.4 6.8 4.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region U79_P34 PF03064.11 EER26100.1 - 4.4 6.7 16.4 6.1 6.2 11.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF4407 PF14362.1 EER26100.1 - 4.9 6.0 7.6 5.6 5.8 5.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TP53IP5 PF15331.1 EER26100.1 - 6.5 6.5 12.1 8.3 6.2 8.4 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 NARP1 PF12569.3 EER26100.1 - 7.1 5.2 22.8 9 4.9 15.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Uso1_p115_C PF04871.8 EER26101.1 - 0.091 12.6 0.4 0.11 12.4 0.3 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Asp PF00026.18 EER26102.1 - 2.4e-65 220.8 0.1 2.8e-65 220.6 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EER26102.1 - 6.7e-05 22.9 0.0 0.00043 20.2 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EER26102.1 - 0.0011 19.4 0.0 2.3 8.7 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EER26102.1 - 0.0056 16.2 0.0 0.04 13.4 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal SAP PF02037.22 EER26103.1 - 2.7e-11 42.7 0.0 4.2e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 SAP domain APH PF01636.18 EER26104.1 - 7.3e-10 38.9 0.0 2.1e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EER26104.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase FMN_dh PF01070.13 EER26106.1 - 1.7e-109 365.9 0.0 2.1e-109 365.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EER26106.1 - 2.3e-16 59.3 0.0 5.2e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EER26106.1 - 0.00031 19.7 0.0 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EER26106.1 - 0.0051 15.9 0.0 0.41 9.6 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EER26106.1 - 0.03 13.2 0.1 0.07 11.9 0.0 1.6 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain TatD_DNase PF01026.16 EER26107.1 - 3.8e-48 163.9 0.0 4.4e-48 163.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Y_phosphatase2 PF03162.8 EER26108.1 - 3.9e-45 153.1 0.1 5.3e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EER26108.1 - 3.8e-09 37.0 0.0 7.3e-08 32.8 0.0 2.1 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EER26108.1 - 3.5e-06 26.6 0.1 4.7e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EER26108.1 - 1.3e-05 24.7 0.2 0.00012 21.4 0.1 2.0 1 1 1 2 2 2 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 EER26108.1 - 0.053 12.2 0.0 0.71 8.5 0.0 2.0 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Hjc PF01870.13 EER26108.1 - 0.14 11.8 0.0 0.49 10.0 0.0 1.8 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) DUF362 PF04015.7 EER26108.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF362) Aa_trans PF01490.13 EER26110.1 - 1.9e-75 253.8 31.9 2.4e-75 253.5 22.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Rad52_Rad22 PF04098.10 EER26112.1 - 1e-59 200.6 0.0 1.5e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein UBX PF00789.15 EER26113.1 - 1.2e-05 25.3 0.0 3.3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 EER26113.1 - 0.00028 20.6 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Utp11 PF03998.8 EER26113.1 - 0.015 15.1 21.9 0.021 14.6 15.2 1.2 1 0 0 1 1 1 0 Utp11 protein GATA PF00320.22 EER26113.1 - 0.037 13.3 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 GATA zinc finger zf-C2H2_2 PF12756.2 EER26113.1 - 0.084 12.9 1.3 0.13 12.3 0.3 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Crystallin PF00525.13 EER26113.1 - 0.15 12.2 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal SOBP PF15279.1 EER26113.1 - 0.48 10.7 6.0 0.57 10.5 4.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Erp_C PF06780.6 EER26113.1 - 1.1 9.1 14.2 2.1 8.1 9.8 1.5 1 0 0 1 1 1 0 Erp protein C-terminus DUF572 PF04502.8 EER26113.1 - 1.4 8.0 23.0 2 7.5 15.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) PLRV_ORF5 PF01690.12 EER26113.1 - 2.6 7.0 14.3 3.4 6.7 9.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Parvo_coat PF00740.13 EER26113.1 - 4.8 6.0 5.8 6.1 5.6 4.1 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Motile_Sperm PF00635.21 EER26114.1 - 3.2e-21 75.0 0.1 2.9e-15 55.8 0.1 2.5 2 0 0 2 2 2 2 MSP (Major sperm protein) domain DUF2077 PF09850.4 EER26114.1 - 0.00097 18.5 0.1 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2077) AAA_27 PF13514.1 EER26114.1 - 0.0066 14.2 1.2 0.0087 13.8 0.8 1.1 1 0 0 1 1 1 1 AAA domain THOC7 PF05615.8 EER26114.1 - 0.0071 16.6 1.6 0.011 16.0 0.4 1.7 2 0 0 2 2 2 1 Tho complex subunit 7 IncA PF04156.9 EER26114.1 - 0.033 13.7 1.9 0.29 10.6 0.8 2.2 2 0 0 2 2 2 0 IncA protein Med9 PF07544.8 EER26114.1 - 0.037 13.7 0.2 0.098 12.4 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Prefoldin_2 PF01920.15 EER26114.1 - 0.043 13.5 1.7 0.09 12.5 1.1 1.5 1 0 0 1 1 1 0 Prefoldin subunit FlxA PF14282.1 EER26114.1 - 0.093 12.6 4.1 0.21 11.5 2.9 1.5 1 0 0 1 1 1 0 FlxA-like protein Sec8_exocyst PF04048.9 EER26114.1 - 0.093 12.3 1.5 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Herpes_UL3 PF03369.8 EER26114.1 - 0.097 12.6 0.1 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus UL3 protein FA_desaturase PF00487.19 EER26115.1 - 7.2e-24 84.6 13.4 1.7e-23 83.3 9.3 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EER26115.1 - 4.2e-19 67.5 0.1 6.7e-19 66.8 0.1 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Peptidase_M24 PF00557.19 EER26116.1 - 1.7e-45 155.1 0.0 2.3e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Pectinesterase PF01095.14 EER26116.1 - 0.024 13.2 0.0 0.036 12.6 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase YL1 PF05764.8 EER26116.1 - 0.13 11.8 9.0 0.21 11.1 6.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TRAP_alpha PF03896.11 EER26116.1 - 0.21 10.5 3.5 0.34 9.8 2.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PGA2 PF07543.7 EER26116.1 - 0.79 9.5 7.3 1.7 8.4 5.1 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.9 EER26116.1 - 7.1 4.5 6.3 9.4 4.1 4.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DnaJ PF00226.26 EER26117.1 - 1.6e-20 72.5 1.8 3.9e-20 71.3 1.2 1.7 1 0 0 1 1 1 1 DnaJ domain zf-B_box PF00643.19 EER26117.1 - 2 8.3 7.2 10 6.1 5.2 2.0 1 1 1 2 2 2 0 B-box zinc finger DNA_pol_viral_N PF00242.12 EER26117.1 - 2.5 7.0 18.9 0.28 10.1 10.2 1.5 2 0 0 2 2 2 0 DNA polymerase (viral) N-terminal domain Sporozoite_P67 PF05642.6 EER26117.1 - 2.6 5.8 6.2 3.5 5.3 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DnaJ PF00226.26 EER26118.1 - 3.7e-23 81.0 0.5 3.7e-23 81.0 0.4 2.0 2 0 0 2 2 2 1 DnaJ domain PAT1 PF09770.4 EER26118.1 - 0.44 8.7 4.9 0.48 8.5 3.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Porin_3 PF01459.17 EER26119.1 - 1e-69 234.9 2.3 1.1e-69 234.7 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin YL1_C PF08265.6 EER26119.1 - 0.051 13.1 0.8 0.29 10.7 0.0 2.4 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Asn_synthase PF00733.16 EER26120.1 - 2.5e-67 227.0 0.0 3.3e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EER26120.1 - 2.1e-35 121.1 0.0 7e-35 119.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EER26120.1 - 3.9e-27 94.8 0.0 1.7e-26 92.7 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EER26120.1 - 1.5e-07 30.8 0.0 2.6e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EER26120.1 - 0.00054 18.7 0.0 0.0013 17.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EER26120.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 NAD synthase UQ_con PF00179.21 EER26121.1 - 3.5e-48 162.6 0.0 3.9e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER26121.1 - 4.6e-06 26.4 0.0 8.1e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EER26121.1 - 0.045 13.6 0.5 0.068 13.0 0.4 1.7 1 1 0 1 1 1 0 RWD domain G-patch PF01585.18 EER26122.1 - 4.7e-11 42.2 1.6 9.1e-11 41.3 1.1 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EER26122.1 - 8.3e-06 25.5 0.1 1.6e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER26122.1 - 0.00013 21.5 0.4 0.00049 19.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER26122.1 - 0.007 16.3 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EER26122.1 - 0.013 15.3 0.4 0.047 13.5 0.3 2.0 1 0 0 1 1 1 0 DExH-box splicing factor binding site AMP-binding PF00501.23 EER26123.1 - 1.2e-83 280.8 0.0 1.5e-83 280.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER26123.1 - 8.7e-12 45.8 0.1 2.8e-11 44.2 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EER26123.1 - 8e-05 21.3 0.0 0.0011 17.6 0.0 2.0 2 0 0 2 2 2 1 GH3 auxin-responsive promoter YCII PF03795.9 EER26124.1 - 8.4e-07 29.1 0.0 1.4e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Anp1 PF03452.9 EER26125.1 - 8.6e-105 349.7 0.1 1.2e-104 349.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 Ecm33 PF12454.3 EER26126.1 - 1.5e-13 50.3 0.0 4.4e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 GPI-anchored cell wall organization protein Recep_L_domain PF01030.19 EER26126.1 - 3.6e-08 33.3 6.4 0.021 14.8 0.0 4.6 1 1 5 6 6 6 4 Receptor L domain LRR_5 PF13306.1 EER26126.1 - 0.0017 18.0 3.1 0.77 9.4 0.5 2.6 1 1 0 2 2 2 2 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EER26126.1 - 0.013 15.2 1.5 0.043 13.5 0.3 2.5 2 0 0 2 2 2 0 Leucine rich repeat AA_permease_2 PF13520.1 EER26127.1 - 2.1e-50 171.5 42.6 2.9e-50 171.0 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER26127.1 - 7.1e-23 80.6 41.3 9.4e-23 80.2 28.6 1.1 1 0 0 1 1 1 1 Amino acid permease YibE_F PF07907.6 EER26127.1 - 0.0063 15.7 2.1 0.0063 15.7 1.5 3.1 3 1 0 3 3 3 1 YibE/F-like protein HhH-GPD PF00730.20 EER26128.1 - 1.2e-15 57.7 0.1 9.4e-15 54.8 0.1 2.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein IER PF05760.7 EER26128.1 - 0.42 10.5 8.1 0.72 9.7 5.6 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) PAT1 PF09770.4 EER26128.1 - 4.3 5.4 6.1 6.2 4.9 4.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cupin_1 PF00190.17 EER26129.1 - 1.2e-26 92.8 0.0 3.6e-13 49.1 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EER26129.1 - 3.4e-22 77.7 0.7 1e-10 40.9 0.1 2.7 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EER26129.1 - 1.3e-05 24.5 0.1 0.0036 16.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EER26129.1 - 0.0083 15.8 0.6 2.6 7.7 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EER26129.1 - 0.013 15.1 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 Cupin UCR_14kD PF02271.11 EER26130.1 - 1.2e-44 150.3 1.1 1.6e-44 149.9 0.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF1845 PF08900.6 EER26130.1 - 0.0088 15.3 0.1 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1845) UIM PF02809.15 EER26130.1 - 1.3 8.7 3.3 1.8 8.3 0.7 2.4 2 0 0 2 2 2 0 Ubiquitin interaction motif Mito_carr PF00153.22 EER26131.1 - 1.9e-67 223.0 0.0 2.1e-23 81.8 0.0 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein ABC1 PF03109.11 EER26132.1 - 2.7e-34 117.6 0.0 4.3e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EER26132.1 - 0.015 14.6 0.1 0.032 13.5 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EER26133.1 - 4.4e-69 232.5 0.0 1.3e-68 230.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26133.1 - 5.3e-51 173.1 0.0 1.3e-50 171.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26133.1 - 0.0047 15.9 0.0 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like HEAT PF02985.17 EER26133.1 - 0.3 11.2 1.2 2.1e+02 2.4 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat FBP PF07299.6 EER26133.1 - 0.33 10.2 1.0 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) Mur_ligase_M PF08245.7 EER26134.1 - 9.7e-09 35.5 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EER26134.1 - 0.0064 16.5 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain SRC-1 PF08832.5 EER26135.1 - 0.0086 16.8 0.1 0.0086 16.8 0.1 2.8 2 0 0 2 2 2 1 Steroid receptor coactivator Zeta_toxin PF06414.7 EER26136.1 - 2.3e-05 23.5 0.6 0.0065 15.5 0.0 2.1 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EER26136.1 - 4e-05 23.9 0.0 0.004 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER26136.1 - 4.8e-05 24.1 0.4 0.00048 20.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EER26136.1 - 0.0014 18.8 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER26136.1 - 0.0014 18.5 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EER26136.1 - 0.0026 17.3 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EER26136.1 - 0.0055 15.6 0.0 0.0099 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 EER26136.1 - 0.015 15.6 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EER26136.1 - 0.028 13.8 0.1 0.052 12.9 0.0 1.6 1 1 1 2 2 2 0 AAA-like domain KAP_NTPase PF07693.9 EER26136.1 - 0.03 13.3 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Thymidylate_kin PF02223.12 EER26136.1 - 0.03 13.6 0.0 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_16 PF13191.1 EER26136.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EER26136.1 - 0.05 13.8 0.0 0.097 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EER26136.1 - 0.055 12.5 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EER26136.1 - 0.059 12.2 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein YhfZ_C PF14503.1 EER26136.1 - 0.08 12.2 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 YhfZ C-terminal domain SKI PF01202.17 EER26136.1 - 0.12 12.2 0.1 2 8.2 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase CPT PF07931.7 EER26136.1 - 0.26 10.8 1.3 2.6 7.6 0.1 2.7 2 1 1 3 3 3 0 Chloramphenicol phosphotransferase-like protein DUF1677 PF07911.8 EER26137.1 - 0.12 12.5 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Ribonuc_red_lgC PF02867.10 EER26138.1 - 7.8e-215 714.5 0.0 1.2e-214 713.8 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EER26138.1 - 6.8e-25 86.6 0.0 1.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EER26138.1 - 3.3e-16 59.5 0.1 7.6e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 ATP cone domain DPBB_1 PF03330.13 EER26139.1 - 3.9e-05 23.5 0.1 0.00011 22.1 0.1 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel ELFV_dehydrog PF00208.16 EER26140.1 - 1.8e-80 270.0 0.5 2.2e-80 269.7 0.4 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EER26140.1 - 4.7e-47 158.8 0.0 9.7e-47 157.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EER26140.1 - 0.1 12.8 0.0 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding HATPase_c_3 PF13589.1 EER26141.1 - 2.6e-21 75.6 0.0 4.6e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EER26141.1 - 7.6e-12 45.0 0.0 7.6e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EER26141.1 - 0.0029 17.2 0.0 0.0059 16.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Xan_ur_permease PF00860.15 EER26142.1 - 0.12 10.8 0.5 0.17 10.3 0.3 1.1 1 0 0 1 1 1 0 Permease family adh_short PF00106.20 EER26143.1 - 5.6e-21 75.1 0.0 1.4e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER26143.1 - 6.2e-08 32.5 0.1 2.2e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EER26143.1 - 6.8e-07 29.2 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EER26143.1 - 0.017 14.8 0.1 0.96 9.2 0.0 2.8 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GHMP_kinases_N PF00288.21 EER26144.1 - 5.2e-14 52.0 0.0 1.1e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EER26144.1 - 0.00072 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Med5 PF08689.5 EER26145.1 - 0 1110.1 0.0 0 1109.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF3782 PF12644.2 EER26145.1 - 0.11 12.3 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) DUF3984 PF13136.1 EER26147.1 - 1e-101 340.4 21.7 1e-101 340.4 15.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3984) OTCace_N PF02729.16 EER26148.1 - 1.3e-43 148.0 0.0 2.5e-43 147.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EER26148.1 - 9.3e-42 142.5 0.0 1.4e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3712 PF12505.3 EER26149.1 - 8.7e-09 35.4 1.2 9.9e-08 32.0 0.3 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EER26149.1 - 0.0015 18.8 1.4 0.6 10.5 0.0 3.5 3 1 0 3 3 3 2 Late embryogenesis abundant protein ALS_ss_C PF10369.4 EER26150.1 - 4.5e-18 64.7 0.0 8.1e-17 60.7 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EER26150.1 - 5.7e-11 41.6 0.1 9.7e-11 40.9 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EER26150.1 - 5e-09 35.8 0.2 1.1e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.1 EER26150.1 - 0.024 14.3 0.1 9 6.0 0.0 2.6 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.24 EER26151.1 - 1.5e-11 43.7 0.0 6.7e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EER26151.1 - 6.4e-07 28.8 1.4 3.8e-05 23.2 0.2 2.7 2 0 0 2 2 2 2 KH domain Peptidase_S64 PF08192.6 EER26151.1 - 0.43 8.8 1.2 0.58 8.4 0.8 1.1 1 0 0 1 1 1 0 Peptidase family S64 Helicase_C PF00271.26 EER26152.1 - 2.4e-18 65.7 0.0 3.5e-14 52.4 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EER26152.1 - 7.7e-18 64.5 0.0 1e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EER26152.1 - 0.057 12.2 0.1 0.095 11.4 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain COG6 PF06419.6 EER26152.1 - 0.13 10.3 0.0 0.18 9.8 0.0 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 PPR_3 PF13812.1 EER26153.1 - 4.4e-08 32.7 0.5 1.6 9.1 0.0 6.2 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EER26153.1 - 1.3e-06 28.2 0.4 0.34 10.9 0.0 4.5 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 EER26153.1 - 2.2e-06 27.2 5.5 0.19 11.7 0.0 6.1 6 0 0 6 6 6 2 PPR repeat dDENN PF03455.14 EER26153.1 - 0.094 12.8 0.7 4 7.5 0.0 3.2 3 0 0 3 3 3 0 dDENN domain MRP-S25 PF13741.1 EER26154.1 - 4.8e-91 304.3 5.5 5.5e-91 304.1 3.8 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EER26154.1 - 0.022 14.6 0.0 8.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 SOG2 PF10428.4 EER26155.1 - 3.6e-99 332.4 0.8 3.6e-99 332.4 0.6 2.8 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 EER26155.1 - 1.7e-15 56.2 7.1 3e-06 26.7 0.3 3.8 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER26155.1 - 1.6e-12 46.9 5.3 2.9e-07 30.1 1.6 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EER26155.1 - 1.6e-10 39.4 6.4 0.054 13.5 0.0 6.2 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EER26155.1 - 3.1e-07 29.4 4.0 20 5.9 0.0 6.2 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EER26155.1 - 0.012 15.6 6.4 4.6 7.6 0.0 5.8 5 1 1 6 6 6 0 Leucine Rich repeat Peptidase_S10 PF00450.17 EER26156.1 - 5.9e-87 292.5 0.2 2.7e-86 290.3 0.1 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EER26156.1 - 0.00054 19.9 0.0 0.0046 16.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Tcp11 PF05794.8 EER26157.1 - 1.7e-89 300.5 0.0 2.1e-89 300.3 0.0 1.0 1 0 0 1 1 1 1 T-complex protein 11 Ydc2-catalyt PF09159.5 EER26158.1 - 3.2e-93 312.2 0.2 4.1e-93 311.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SAP PF02037.22 EER26158.1 - 0.0011 18.4 2.3 0.0022 17.4 0.1 2.5 2 0 0 2 2 2 1 SAP domain Pox_A22 PF04848.8 EER26158.1 - 0.0079 16.0 0.0 4.3 7.2 0.0 3.3 3 0 0 3 3 3 1 Poxvirus A22 protein PT PF04886.7 EER26159.1 - 4.3 6.7 27.6 1.5e+04 -8.6 19.1 4.1 1 1 0 1 1 1 0 PT repeat CTP_transf_2 PF01467.21 EER26160.1 - 0.0099 15.9 0.0 0.023 14.7 0.0 1.7 2 0 0 2 2 2 1 Cytidylyltransferase Oxidored_FMN PF00724.15 EER26160.1 - 0.11 11.5 0.2 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family DUF2416 PF10315.4 EER26161.1 - 9.3e-06 25.8 0.0 2.3e-05 24.5 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2416) DUF1977 PF09320.6 EER26162.1 - 2.8e-29 101.5 0.1 5.1e-29 100.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EER26162.1 - 4.9e-24 83.8 0.7 8.1e-24 83.1 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain ADP_ribosyl_GH PF03747.9 EER26162.1 - 0.069 12.9 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Ufd2P_core PF10408.4 EER26163.1 - 1.4e-201 671.0 10.7 1.7e-201 670.7 7.4 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EER26163.1 - 3.7e-24 84.4 1.6 6.6e-24 83.6 0.2 2.2 2 0 0 2 2 2 1 U-box domain Steroid_dh PF02544.11 EER26164.1 - 5.5e-09 35.9 11.6 5.1e-06 26.3 1.7 3.9 3 1 0 3 3 3 2 3-oxo-5-alpha-steroid 4-dehydrogenase Meth_synt_2 PF01717.13 EER26165.1 - 6.9e-144 478.7 0.0 2.1e-140 467.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EER26165.1 - 4.6e-122 407.1 0.0 5.5e-110 367.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Bac_small_YrzI PF09501.5 EER26165.1 - 2.6 8.0 5.0 3.3 7.7 1.7 2.4 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) Myb_DNA-bind_6 PF13921.1 EER26167.1 - 0.0053 16.8 0.0 0.018 15.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER26167.1 - 0.054 13.5 0.0 0.55 10.3 0.0 2.5 1 1 0 1 1 1 0 Myb-like DNA-binding domain ASFV_J13L PF05568.6 EER26167.1 - 0.19 11.2 5.9 0.4 10.2 4.1 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein ATP-synt_E PF05680.7 EER26167.1 - 1.5 8.8 10.6 6.6 6.7 3.0 3.4 3 0 0 3 3 3 0 ATP synthase E chain EMP24_GP25L PF01105.19 EER26168.1 - 2e-51 174.3 0.0 2.5e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD adh_short PF00106.20 EER26169.1 - 6e-33 114.1 1.0 8e-33 113.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER26169.1 - 4.3e-23 82.3 0.0 5.2e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER26169.1 - 2.6e-14 53.2 0.6 3.7e-14 52.7 0.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EER26169.1 - 1.1e-06 28.3 0.5 7.5e-06 25.5 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EER26169.1 - 0.0067 16.1 0.2 0.018 14.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EER26169.1 - 0.043 12.7 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Prenyltransf PF01255.14 EER26169.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase DUF1712 PF08217.6 EER26170.1 - 1.4e-17 63.2 0.0 5e-15 54.7 0.0 2.4 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) DUF3432 PF11914.3 EER26171.1 - 1.9 8.5 15.5 13 5.8 7.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) PNK3P PF08645.6 EER26172.1 - 3.2e-51 172.9 0.0 5.8e-51 172.0 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EER26172.1 - 5.9e-33 113.7 0.0 1.7e-31 109.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EER26172.1 - 9.6e-07 28.2 0.1 0.0022 17.2 0.0 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EER26172.1 - 0.0027 16.8 0.0 0.024 13.7 0.0 2.4 1 1 2 3 3 3 1 Zeta toxin AAA_22 PF13401.1 EER26172.1 - 0.038 14.1 0.0 0.067 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain GvpD PF07088.6 EER26172.1 - 0.15 10.3 0.0 0.28 9.4 0.0 1.4 1 0 0 1 1 1 0 GvpD gas vesicle protein Med18 PF09637.5 EER26173.1 - 1.4e-67 227.8 0.0 1.6e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Med18 protein DUF2638 PF10937.3 EER26174.1 - 8.8e-40 136.2 0.2 1e-39 136.0 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EER26175.1 - 5.9e-90 300.8 6.3 8.6e-90 300.2 4.4 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis HTH_39 PF14090.1 EER26175.1 - 0.0087 15.5 0.0 0.047 13.1 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain RGS PF00615.14 EER26176.1 - 3.1e-13 49.8 0.0 4.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Pkinase PF00069.20 EER26177.1 - 4.8e-36 124.2 0.0 6e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26177.1 - 1.6e-14 53.6 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER26177.1 - 0.013 15.2 0.0 0.46 10.1 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Rtt106 PF08512.7 EER26178.1 - 5e-25 87.3 0.0 1.5e-24 85.7 0.0 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like KOW PF00467.24 EER26179.1 - 6.5e-07 28.8 0.3 6.5e-07 28.8 0.2 2.0 2 0 0 2 2 2 1 KOW motif Ras PF00071.17 EER26180.1 - 1.5e-54 183.7 0.0 1.7e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER26180.1 - 4.8e-15 56.0 0.0 7.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER26180.1 - 1.8e-07 30.5 0.0 3.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EER26180.1 - 0.00082 18.6 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EER26180.1 - 0.023 13.8 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Alg14 PF08660.6 EER26181.1 - 7.2e-50 169.2 0.0 1.6e-47 161.6 0.0 2.2 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like IncA PF04156.9 EER26181.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 IncA protein Ima1_N PF09779.4 EER26182.1 - 2.9e-43 147.5 10.8 4.6e-43 146.8 7.5 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Zn_Tnp_IS1595 PF12760.2 EER26182.1 - 0.0067 16.2 4.0 0.0067 16.2 2.8 2.4 2 0 0 2 2 2 1 Transposase zinc-ribbon domain DUF2938 PF11158.3 EER26182.1 - 0.051 12.9 1.0 0.09 12.1 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2938) OrfB_Zn_ribbon PF07282.6 EER26182.1 - 0.08 12.6 1.4 0.24 11.0 0.9 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DZR PF12773.2 EER26182.1 - 1.9 8.3 7.0 7.8 6.4 1.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Rax2 PF12768.2 EER26183.1 - 0.016 14.3 0.4 0.016 14.3 0.3 1.6 1 1 1 2 2 2 0 Cortical protein marker for cell polarity Chorismate_synt PF01264.16 EER26184.1 - 4.8e-131 436.3 0.0 5.7e-131 436.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase BPL_LplA_LipB PF03099.14 EER26185.1 - 6.4e-11 42.3 0.0 1.6e-10 41.0 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Kelch_4 PF13418.1 EER26186.1 - 0.0011 18.7 11.8 1.4 8.7 0.0 5.5 5 1 0 5 5 5 3 Galactose oxidase, central domain Pkinase PF00069.20 EER26187.1 - 2.7e-54 184.0 0.1 2.8e-37 128.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER26187.1 - 6.6e-27 94.2 0.0 5.7e-26 91.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26187.1 - 5.6e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER26187.1 - 0.0014 18.4 0.0 0.0073 16.0 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family PhoQ_Sensor PF08918.5 EER26187.1 - 0.24 10.8 0.1 0.47 9.9 0.0 1.4 1 0 0 1 1 1 0 PhoQ Sensor zf-H2C2_2 PF13465.1 EER26188.1 - 1.5e-13 50.3 8.1 5.6e-08 32.6 0.2 3.7 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER26188.1 - 5.4e-11 42.0 12.2 2.7e-05 24.1 1.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EER26188.1 - 1.3e-10 40.9 17.4 5.7e-06 26.3 1.5 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EER26188.1 - 8.2e-07 28.9 2.1 0.08 13.1 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EER26188.1 - 5.4e-05 23.2 1.4 0.018 15.2 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EER26188.1 - 0.14 12.2 1.6 0.27 11.3 1.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Zn_ribbon_recom PF13408.1 EER26188.1 - 0.18 12.0 0.6 0.4 10.9 0.4 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-BED PF02892.10 EER26188.1 - 0.51 10.1 4.4 1.7 8.4 0.7 2.6 1 1 1 2 2 2 0 BED zinc finger LIM PF00412.17 EER26188.1 - 0.64 10.1 2.9 3.8 7.6 2.0 2.2 1 1 1 2 2 2 0 LIM domain zf-C2H2_6 PF13912.1 EER26188.1 - 0.75 9.7 7.7 18 5.4 0.3 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.16 EER26188.1 - 5.2 7.0 6.3 11 5.9 4.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger Glycos_transf_1 PF00534.15 EER26189.1 - 2.5e-15 56.2 0.0 4.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EER26189.1 - 1.9e-05 24.8 0.0 0.0001 22.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EER26189.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 60KD_IMP PF02096.15 EER26190.1 - 7.3e-20 71.4 0.7 9e-20 71.1 0.5 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein GIIM PF08388.6 EER26190.1 - 0.0015 18.2 2.1 0.0026 17.4 0.3 2.3 2 1 0 2 2 2 1 Group II intron, maturase-specific domain ExoD PF06055.7 EER26190.1 - 0.039 13.0 0.5 0.1 11.7 0.4 1.7 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD PP2C PF00481.16 EER26191.1 - 5.5e-45 153.7 0.0 1.3e-44 152.5 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EER26191.1 - 1.6e-06 27.6 0.1 5.9e-06 25.8 0.0 1.9 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EER26191.1 - 0.00043 20.0 0.0 0.073 12.7 0.0 2.8 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.9 EER26192.1 - 2.3e-86 289.9 0.1 3.6e-86 289.3 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PQ-loop PF04193.9 EER26193.1 - 7.8e-40 134.2 12.1 1.3e-21 75.9 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat Ribosomal_60s PF00428.14 EER26194.1 - 7.7e-25 87.1 11.8 9.5e-25 86.8 8.2 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 EER26195.1 - 4.1e-55 185.5 3.5 9.7e-32 109.8 0.1 5.1 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) DUF3336 PF11815.3 EER26195.1 - 0.033 13.7 0.4 0.33 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3336) PTRF_SDPR PF15237.1 EER26195.1 - 0.054 12.8 1.0 0.15 11.4 0.1 2.0 2 0 0 2 2 2 0 PTRF/SDPR family Cob_adeno_trans PF01923.13 EER26195.1 - 0.065 13.0 0.5 1.9 8.2 0.1 2.6 1 1 2 3 3 3 0 Cobalamin adenosyltransferase Spore_III_AB PF09548.5 EER26195.1 - 0.22 11.2 2.9 1.7 8.3 0.1 2.8 4 0 0 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) NBP1 PF08537.5 EER26195.1 - 0.52 9.4 2.6 0.38 9.9 0.1 2.0 3 0 0 3 3 3 0 Fungal Nap binding protein NBP1 Aconitase PF00330.15 EER26196.1 - 6.5e-159 529.3 0.0 1.8e-158 527.8 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EER26196.1 - 7.6e-40 136.0 0.0 1.2e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain NmrA PF05368.8 EER26197.1 - 7.5e-25 87.5 0.0 9.3e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EER26197.1 - 4.1e-08 33.4 0.0 9.3e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EER26197.1 - 3.3e-06 26.0 0.0 4.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EER26197.1 - 0.00047 20.4 0.0 0.0015 18.8 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EER26197.1 - 0.0021 17.5 0.0 0.035 13.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EER26197.1 - 0.037 12.9 0.1 0.054 12.4 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase HEAT_EZ PF13513.1 EER26198.1 - 2.3e-19 69.2 5.7 8.7e-05 22.8 0.1 10.0 6 2 3 10 10 10 4 HEAT-like repeat HEAT_2 PF13646.1 EER26198.1 - 2e-17 63.2 7.7 0.0022 18.2 0.0 8.8 5 2 3 9 9 9 4 HEAT repeats HEAT PF02985.17 EER26198.1 - 6.7e-17 60.0 7.8 0.13 12.4 0.0 11.0 11 0 0 11 11 11 3 HEAT repeat Vac14_Fab1_bd PF12755.2 EER26198.1 - 5.2e-08 33.1 0.1 0.051 13.9 0.0 6.6 3 2 5 8 8 8 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EER26198.1 - 3.8e-07 29.1 0.3 0.021 13.5 0.0 5.2 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EER26198.1 - 1.8e-06 27.6 0.0 0.0046 16.6 0.0 4.6 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.3 EER26198.1 - 1.2e-05 24.8 0.7 0.0012 18.2 0.1 4.0 4 1 0 4 4 4 1 CLASP N terminal Arm PF00514.18 EER26198.1 - 4.4e-05 23.1 3.1 1.9 8.4 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 EER26198.1 - 0.00028 20.8 0.2 2.9 7.8 0.1 4.8 3 2 1 5 5 5 1 Domain of unknown function (DUF3385) TFCD_C PF12612.3 EER26198.1 - 0.0004 19.8 0.1 4.4 6.6 0.0 4.1 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal IBN_N PF03810.14 EER26198.1 - 0.0014 18.5 0.3 0.027 14.3 0.0 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain V-ATPase_H_N PF03224.9 EER26198.1 - 0.081 12.0 2.3 1.8 7.6 0.0 3.5 3 1 0 3 3 3 0 V-ATPase subunit H CBS PF00571.23 EER26199.1 - 3.6e-41 138.6 7.9 5.9e-11 41.9 0.0 4.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EER26199.1 - 4.6e-10 39.0 0.0 2e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 PB1 domain Ribosomal_S26e PF01283.14 EER26200.1 - 1.7e-51 173.2 8.1 2e-51 173.0 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 EER26200.1 - 0.014 15.7 0.3 3.6 7.9 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain Fer4_7 PF12838.2 EER26200.1 - 0.038 14.3 0.7 1.6 9.1 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Njmu-R1 PF15053.1 EER26200.1 - 0.13 10.9 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family F-box-like PF12937.2 EER26201.1 - 2.3e-05 24.0 1.9 2.8e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EER26201.1 - 0.063 12.9 0.1 0.063 12.9 0.1 2.6 3 0 0 3 3 3 0 F-box domain LRR_6 PF13516.1 EER26201.1 - 0.12 12.4 7.4 17 5.8 0.1 5.4 7 0 0 7 7 7 0 Leucine Rich repeat Peptidase_C14 PF00656.17 EER26202.1 - 2.1e-72 243.8 0.0 2.5e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EER26202.1 - 0.083 12.7 0.9 0.3 10.9 0.0 2.3 3 1 1 4 4 4 0 Raptor N-terminal CASPase like domain Cpn60_TCP1 PF00118.19 EER26203.1 - 7.9e-142 473.2 4.2 9.2e-142 473.0 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HSDR_N_2 PF13588.1 EER26203.1 - 0.072 12.8 0.0 0.38 10.5 0.0 2.2 3 0 0 3 3 3 0 Type I restriction enzyme R protein N terminus (HSDR_N) zf-H2C2 PF09337.5 EER26204.1 - 5.2e-21 73.7 5.5 8.6e-21 73.0 3.8 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EER26204.1 - 0.00099 19.1 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EER26204.1 - 0.0045 16.9 0.0 0.013 15.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EER26204.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF367 PF04034.8 EER26205.1 - 1.6e-48 163.4 0.0 2.5e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EER26205.1 - 7.1e-11 41.4 0.5 1.6e-10 40.3 0.4 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI CDC45 PF02724.9 EER26205.1 - 1.4 6.9 5.9 1.7 6.5 4.1 1.2 1 0 0 1 1 1 0 CDC45-like protein VHS PF00790.14 EER26206.1 - 3.7e-46 156.2 0.0 1.2e-45 154.5 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EER26206.1 - 3.7e-24 84.6 2.1 7.7e-24 83.5 0.7 2.1 2 0 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.15 EER26206.1 - 9.9e-21 74.1 0.7 9.9e-21 74.1 0.5 2.1 2 0 0 2 2 2 1 Adaptin C-terminal domain Transpep_BrtH PF14399.1 EER26206.1 - 0.17 11.1 2.2 0.3 10.3 1.5 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase GLTSCR1 PF15249.1 EER26206.1 - 1.1 9.3 5.6 36 4.5 3.9 2.4 1 1 0 1 1 1 0 Glioma tumor suppressor candidate region CBS PF00571.23 EER26208.1 - 1.2e-19 69.8 0.1 5.9e-05 22.7 0.0 5.3 5 0 0 5 5 5 5 CBS domain DUF3482 PF11981.3 EER26210.1 - 0.081 12.1 7.4 0.13 11.4 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) TMF_DNA_bd PF12329.3 EER26210.1 - 0.12 12.1 9.2 0.75 9.6 2.6 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EER26210.1 - 0.14 12.0 2.9 0.26 11.1 2.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2183 PF09949.4 EER26211.1 - 8.4e-32 109.0 0.0 1.8e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EER26211.1 - 0.00098 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) ADH_zinc_N_2 PF13602.1 EER26212.1 - 4.4e-16 59.9 0.0 6.9e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER26212.1 - 0.0016 18.1 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GPP34 PF05719.6 EER26213.1 - 2.1e-63 214.1 0.1 2.6e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) PP-binding PF00550.20 EER26214.1 - 9.9e-12 44.9 0.3 1.7e-11 44.2 0.2 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EER26214.1 - 1.9e-06 27.7 0.2 3.3e-06 27.0 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier Fer4 PF00037.22 EER26215.1 - 1.6e-13 49.6 16.5 5.6e-08 32.0 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EER26215.1 - 3.7e-12 46.4 10.5 5.9e-12 45.7 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EER26215.1 - 2e-09 37.0 22.1 5.8e-08 32.4 8.5 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EER26215.1 - 2.8e-09 37.0 11.0 5.4e-09 36.1 7.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EER26215.1 - 6e-09 36.5 8.9 0.00024 21.7 0.4 2.5 3 0 0 3 3 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EER26215.1 - 1.1e-08 34.7 31.9 1.4e-05 24.8 8.6 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.1 EER26215.1 - 5.8e-08 32.6 19.7 1.5e-05 24.9 7.8 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EER26215.1 - 1.4e-07 31.0 14.7 0.00045 19.9 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EER26215.1 - 2.7e-07 30.1 17.1 0.0013 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EER26215.1 - 5.6e-06 26.2 12.7 0.0006 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EER26215.1 - 1e-05 25.8 10.3 0.00082 19.6 7.8 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EER26215.1 - 4.9e-05 23.6 9.7 0.015 15.7 0.6 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EER26215.1 - 0.0083 16.4 15.1 0.31 11.4 3.2 2.7 2 1 1 3 3 3 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EER26215.1 - 0.016 15.7 13.3 0.3 11.6 1.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EER26215.1 - 0.077 13.6 16.9 0.16 12.5 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EER26215.1 - 0.13 12.4 4.8 0.14 12.2 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain SURF6 PF04935.7 EER26216.1 - 7.1e-54 182.3 36.7 7.1e-54 182.3 25.4 3.8 3 1 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EER26216.1 - 2.5e-23 81.9 1.0 2.5e-23 81.9 0.7 8.4 6 2 2 8 8 8 2 60S ribosome biogenesis protein Rrp14 Peptidase_S8 PF00082.17 EER26218.1 - 9.2e-44 149.6 6.4 1.6e-43 148.8 4.5 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER26218.1 - 6.3e-17 61.9 0.0 1.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Rick_17kDa_Anti PF05433.10 EER26219.1 - 8.7e-06 25.3 10.1 8.7e-06 25.3 7.0 2.5 3 0 0 3 3 3 1 Glycine zipper 2TM domain Med15 PF09606.5 EER26219.1 - 1.7 6.7 30.6 1.7 6.7 21.2 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TraT PF05818.7 EER26219.1 - 2.9 7.2 7.0 2.8 7.2 4.0 1.6 1 1 0 1 1 1 0 Enterobacterial TraT complement resistance protein Ribosomal_S2 PF00318.15 EER26220.1 - 7.5e-52 175.6 0.0 1.1e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S2 COPI_assoc PF08507.5 EER26220.1 - 0.15 11.7 0.1 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 COPI associated protein Mito_carr PF00153.22 EER26221.1 - 4.4e-63 209.0 1.6 5.3e-20 70.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.22 EER26222.1 - 9.3e-38 129.5 4.0 4.6e-37 127.2 2.8 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EER26222.1 - 2e-26 92.0 2.0 5.2e-26 90.6 1.4 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EER26222.1 - 8.8e-13 48.1 2.3 8.7e-07 28.9 0.1 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EER26222.1 - 1.5e-08 34.5 0.0 3.9e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 EER26222.1 - 2.7e-08 33.3 0.0 1.3e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 EER26222.1 - 8e-05 23.1 0.1 0.00019 21.8 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER26222.1 - 9.6e-05 21.6 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EER26222.1 - 0.0015 17.7 0.0 0.0036 16.5 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EER26222.1 - 0.0048 16.1 0.5 0.015 14.5 0.4 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EER26222.1 - 0.012 15.1 0.1 0.029 13.8 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EER26222.1 - 0.015 14.6 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Ras family GTP_EFTU_D4 PF14578.1 EER26222.1 - 0.016 14.8 2.9 0.064 12.8 0.5 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 EER26222.1 - 0.025 14.4 5.0 3.1 7.5 0.1 3.8 3 1 1 4 4 4 0 Dynamin family Rtf2 PF04641.7 EER26222.1 - 1.9 7.6 8.5 0.57 9.3 0.2 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger Ceramidase_alk PF04734.8 EER26224.1 - 3.3e-270 897.7 0.0 3.8e-270 897.5 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase BCAS2 PF05700.6 EER26225.1 - 1.1e-57 195.0 0.5 1.2e-57 194.8 0.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Sugarporin_N PF11471.3 EER26225.1 - 6.7 6.4 10.1 1.3 8.7 1.4 2.4 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Kelch_5 PF13854.1 EER26226.1 - 8.8e-20 70.2 5.5 1.2e-09 37.9 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EER26226.1 - 3.1e-14 52.4 8.4 0.029 14.1 0.1 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EER26226.1 - 7.4e-12 45.0 8.5 0.00042 20.3 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EER26226.1 - 3.3e-11 42.8 10.6 0.0015 18.5 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EER26226.1 - 9e-08 31.5 4.8 0.0053 16.4 0.1 4.2 4 0 0 4 4 4 2 Kelch motif SKG6 PF08693.5 EER26226.1 - 4.8e-05 22.5 0.2 0.00014 21.0 0.2 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_1 PF01344.20 EER26226.1 - 0.0078 15.7 11.7 1.1 8.7 0.1 4.7 5 0 0 5 5 5 2 Kelch motif Snf7 PF03357.16 EER26227.1 - 3.9e-36 124.0 13.5 3.9e-36 124.0 9.4 2.0 1 1 1 2 2 2 1 Snf7 DUF3138 PF11336.3 EER26227.1 - 0.2 9.8 1.5 0.25 9.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Fork_head PF00250.13 EER26228.1 - 2.5e-17 62.6 0.1 5.1e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EER26228.1 - 9.1e-05 22.4 0.0 0.00021 21.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain DUF4259 PF14078.1 EER26228.1 - 0.57 10.6 3.6 4.3 7.8 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4259) Sugar_tr PF00083.19 EER26229.1 - 4.4e-52 177.1 19.4 2.9e-30 105.2 7.9 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EER26229.1 - 1.7e-11 43.4 29.0 3.1e-07 29.4 10.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy_3 PF13640.1 EER26231.1 - 4.2e-10 40.0 0.0 7.1e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EER26231.1 - 6.2e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EER26231.1 - 2.2e-05 24.6 0.0 3.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily cNMP_binding PF00027.24 EER26232.1 - 1.7e-45 152.7 0.0 1.1e-22 79.5 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Sugar_tr PF00083.19 EER26233.1 - 7.4e-32 110.4 29.6 5.2e-31 107.6 20.5 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER26233.1 - 9.7e-28 96.8 41.4 2.4e-25 89.0 13.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily WW PF00397.21 EER26234.1 - 1.4e-09 37.6 19.1 1.1e-08 34.8 4.6 3.2 3 0 0 3 3 3 2 WW domain IncA PF04156.9 EER26234.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 IncA protein Gly-zipper_OmpA PF13436.1 EER26234.1 - 0.048 13.3 1.2 0.088 12.4 0.8 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 EER26234.1 - 0.71 9.5 14.1 16 5.2 9.8 2.3 1 1 0 1 1 1 0 Glycine zipper PAP2 PF01569.16 EER26235.1 - 4e-14 52.3 7.1 4e-14 52.3 4.9 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EER26235.1 - 1.8e-07 30.9 6.4 1.8e-07 30.9 4.5 2.2 2 2 1 3 3 3 1 PAP2 superfamily LCAT PF02450.10 EER26236.1 - 1.3e-97 327.2 0.0 1.6e-97 326.9 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EER26236.1 - 0.043 13.6 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 EER26236.1 - 0.056 12.7 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_5 PF12695.2 EER26236.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Yippee-Mis18 PF03226.9 EER26237.1 - 3.4e-25 87.9 0.9 3.8e-25 87.7 0.7 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EER26237.1 - 0.00034 20.5 0.5 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 EER26237.1 - 0.001 19.0 1.1 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.3 EER26237.1 - 0.01 15.6 1.9 0.026 14.3 1.3 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I DUF4451 PF14616.1 EER26237.1 - 0.03 14.0 0.7 0.039 13.7 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Evr1_Alr PF04777.8 EER26237.1 - 0.038 13.8 1.2 0.81 9.6 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family CpXC PF14353.1 EER26237.1 - 0.076 12.9 0.2 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 CpXC protein Endonuclease_7 PF02945.10 EER26237.1 - 0.078 12.6 1.2 0.21 11.3 0.9 1.8 1 1 0 1 1 1 0 Recombination endonuclease VII Pap_E4 PF02711.9 EER26238.1 - 0.0043 17.8 2.0 0.0049 17.6 0.1 2.1 2 0 0 2 2 2 1 E4 protein RabGAP-TBC PF00566.13 EER26239.1 - 4e-34 117.9 1.8 9.3e-34 116.7 1.2 1.7 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EER26240.1 - 2.9e-56 190.5 0.0 5.3e-56 189.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26240.1 - 1.5e-19 70.1 0.0 2.3e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26240.1 - 8.3e-06 24.9 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PAS_9 PF13426.1 EER26240.1 - 0.0031 17.8 0.0 2.9 8.3 0.0 3.6 3 1 0 3 3 3 1 PAS domain RIO1 PF01163.17 EER26240.1 - 0.0047 16.2 0.1 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EER26240.1 - 0.007 16.1 0.1 0.025 14.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family NUDE_C PF04880.8 EER26240.1 - 0.012 15.9 2.3 0.012 15.9 1.6 2.8 4 0 0 4 4 4 0 NUDE protein, C-terminal conserved region LRR_6 PF13516.1 EER26241.1 - 3.8e-15 54.2 20.3 0.044 13.8 0.4 9.3 9 0 0 9 9 9 5 Leucine Rich repeat F-box-like PF12937.2 EER26241.1 - 5.6e-12 45.1 0.6 1.4e-11 43.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER26241.1 - 3e-08 33.1 0.1 1e-07 31.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EER26241.1 - 6.4e-08 32.0 17.5 0.00013 21.4 0.2 6.2 4 2 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EER26241.1 - 2.7e-05 23.6 21.8 1.4 9.2 0.1 8.4 7 2 1 8 8 8 1 Leucine Rich Repeat PRANC PF09372.5 EER26241.1 - 0.00052 19.9 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 PRANC domain LRR_8 PF13855.1 EER26241.1 - 0.00093 18.9 16.3 0.012 15.3 0.9 5.5 4 2 1 6 6 6 2 Leucine rich repeat Recep_L_domain PF01030.19 EER26241.1 - 0.017 15.0 0.7 1 9.3 0.0 3.0 3 0 0 3 3 3 0 Receptor L domain LRR_7 PF13504.1 EER26241.1 - 0.1 12.8 23.0 23 5.7 0.1 8.2 9 0 0 9 9 9 0 Leucine rich repeat DUF2361 PF10153.4 EER26242.1 - 1e-31 109.4 19.7 2e-31 108.5 9.1 3.0 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) DUF1664 PF07889.7 EER26242.1 - 0.21 11.4 1.4 0.39 10.5 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2934 PF11154.3 EER26243.1 - 0.019 14.2 0.2 0.056 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) PTS_2-RNA PF01885.11 EER26244.1 - 2.6e-70 235.5 0.0 3.3e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Stb3 PF10330.4 EER26246.1 - 4.4e-36 122.4 0.0 1.1e-35 121.1 0.0 1.7 1 0 0 1 1 1 1 Putative Sin3 binding protein Mito_carr PF00153.22 EER26248.1 - 1.4e-66 220.1 5.8 5.2e-24 83.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Kri1_C PF12936.2 EER26249.1 - 3.3e-30 103.8 0.1 3.3e-30 103.8 0.0 4.5 3 2 2 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 EER26249.1 - 1.2e-27 96.1 24.5 1.2e-27 96.1 17.0 5.2 6 1 0 6 6 6 1 KRI1-like family PH PF00169.24 EER26250.1 - 1.4e-07 31.6 0.0 3.9e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 PH domain GRAM PF02893.15 EER26250.1 - 0.0011 18.4 0.1 0.0033 16.9 0.0 1.8 1 0 0 1 1 1 1 GRAM domain Sen15 PF09631.5 EER26251.1 - 2.6e-17 62.8 0.0 9.4e-17 61.0 0.0 1.8 1 1 0 1 1 1 1 Sen15 protein UAA PF08449.6 EER26252.1 - 5.8e-76 255.3 6.1 1.5e-75 253.9 4.2 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EER26252.1 - 5.1e-09 36.2 27.0 2.4e-05 24.3 5.4 3.5 3 1 0 3 3 3 3 EamA-like transporter family Nuc_sug_transp PF04142.10 EER26252.1 - 1.4e-07 30.8 0.9 0.0033 16.5 0.2 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EER26252.1 - 4.5e-07 30.0 14.7 2.8e-05 24.3 1.3 2.7 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EER26252.1 - 0.33 10.5 19.7 0.037 13.6 6.0 3.0 2 2 0 2 2 2 0 Triose-phosphate Transporter family DUF4231 PF14015.1 EER26252.1 - 1.4 8.8 6.3 9.1 6.3 0.4 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Rotamase_3 PF13616.1 EER26253.1 - 8.5e-17 61.4 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EER26253.1 - 3.8e-16 59.6 0.1 6e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EER26253.1 - 1.5e-05 25.5 0.1 1.9e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain 2OG-FeII_Oxy_2 PF13532.1 EER26254.1 - 7.6e-14 51.9 0.0 2e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EER26254.1 - 0.00014 22.0 0.0 0.00027 21.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Steroid_dh PF02544.11 EER26255.1 - 2.2e-08 34.0 0.1 5.2e-08 32.7 0.1 1.7 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF3492 PF11997.3 EER26255.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Ank_2 PF12796.2 EER26256.1 - 6e-26 90.6 0.5 3.9e-19 68.7 0.3 2.9 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EER26256.1 - 2.3e-23 81.6 2.2 2.1e-09 37.3 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EER26256.1 - 4.1e-22 76.8 0.8 2.4e-08 33.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EER26256.1 - 4e-16 59.0 0.4 1e-09 38.6 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER26256.1 - 4e-16 57.4 0.0 1.5e-06 27.8 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ribosomal_L7Ae PF01248.21 EER26257.1 - 3.2e-27 93.8 0.8 4.2e-27 93.5 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EER26257.1 - 0.06 12.9 0.1 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Vac_ImportDeg PF09783.4 EER26258.1 - 1.2e-43 148.6 0.2 9.4e-43 145.7 0.0 2.0 2 0 0 2 2 2 1 Vacuolar import and degradation protein IU_nuc_hydro PF01156.14 EER26259.1 - 3.2e-85 286.0 0.0 3.7e-85 285.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase PXA PF02194.10 EER26260.1 - 5e-44 150.0 0.1 7.5e-44 149.5 0.1 1.3 1 0 0 1 1 1 1 PXA domain HTH_Tnp_Tc5 PF03221.11 EER26262.1 - 1.9e-13 50.0 0.0 3.7e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EER26262.1 - 9.8e-07 28.1 0.0 2.4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 EER26262.1 - 0.022 14.4 0.0 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 MarR family HTH_Crp_2 PF13545.1 EER26262.1 - 0.029 14.1 0.0 0.068 12.9 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Sigma70_r4 PF04545.11 EER26262.1 - 0.03 13.6 0.1 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.1 EER26262.1 - 0.061 13.0 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain HTH_24 PF13412.1 EER26262.1 - 0.07 12.5 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EER26262.1 - 0.075 12.7 0.0 0.32 10.7 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_38 PF13936.1 EER26262.1 - 0.1 12.1 0.1 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_Tnp_4 PF13613.1 EER26262.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MTBP_C PF14920.1 EER26262.1 - 0.74 9.2 5.6 1.4 8.3 3.9 1.5 1 0 0 1 1 1 0 MDM2-binding TGS PF02824.16 EER26263.1 - 2.2e-23 81.8 0.1 7.8e-23 80.0 0.1 1.9 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 EER26263.1 - 1.8e-18 66.5 0.1 4.6e-18 65.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EER26263.1 - 7.8e-10 38.2 0.1 5e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EER26263.1 - 2.5e-05 23.7 0.1 0.38 10.1 0.0 4.0 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EER26263.1 - 0.00012 21.9 0.1 0.024 14.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin family Miro PF08477.8 EER26263.1 - 0.0055 17.2 0.0 0.019 15.4 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EER26263.1 - 0.0055 15.5 0.1 0.013 14.3 0.1 1.6 1 0 0 1 1 1 1 ArgK protein AAA_28 PF13521.1 EER26263.1 - 0.16 11.8 0.0 0.71 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain CDO_I PF05995.7 EER26264.1 - 2.4e-41 140.8 0.0 2.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EER26264.1 - 1.2e-08 34.5 0.0 1.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Glyco_transf_90 PF05686.7 EER26265.1 - 4.3e-15 55.3 9.6 9.4e-13 47.6 5.6 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.2 EER26266.1 - 9.6e-23 81.2 1.0 2.4e-22 79.9 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER26266.1 - 6.3e-09 35.7 0.1 1.6e-08 34.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER26266.1 - 3e-08 33.4 0.0 2.9e-07 30.2 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Glyco_transf_8 PF01501.15 EER26267.1 - 1.3e-32 113.1 0.0 1.8e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 HEAT PF02985.17 EER26268.1 - 3.9e-46 151.0 15.3 0.0028 17.5 0.1 13.3 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EER26268.1 - 1e-35 121.8 1.2 1.9e-08 34.4 0.0 7.7 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 EER26268.1 - 7.8e-16 58.0 4.5 0.039 14.4 0.0 9.1 8 3 1 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EER26268.1 - 2e-12 47.3 3.0 0.0007 19.9 0.1 7.4 5 2 5 10 10 10 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EER26268.1 - 1.2e-08 33.8 5.5 5.3e-07 28.3 0.9 3.6 3 1 1 4 4 4 2 Adaptin N terminal region Arm PF00514.18 EER26268.1 - 0.00014 21.5 3.6 1.4 8.8 0.0 5.7 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EER26268.1 - 0.0057 16.5 4.6 0.84 9.5 0.1 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 EER26268.1 - 0.0071 15.3 0.4 0.081 11.9 0.1 2.7 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.3 EER26268.1 - 0.0095 15.3 2.5 7.8 5.7 0.0 4.5 3 1 2 5 5 5 2 CLASP N terminal RIX1 PF08167.7 EER26268.1 - 0.05 13.2 0.1 4 7.0 0.0 3.6 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 EER26268.1 - 0.091 11.0 5.2 0.73 8.0 0.1 3.0 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 EER26268.1 - 0.16 11.8 6.6 5 6.9 0.3 5.1 2 1 4 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Imm25 PF15571.1 EER26268.1 - 0.7 10.0 4.0 7.1 6.7 0.1 3.6 3 2 1 4 4 4 0 Immunity protein 25 B3_4 PF03483.12 EER26269.1 - 2e-24 85.9 0.0 4.5e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EER26269.1 - 1.4e-17 63.2 0.0 1.9e-15 56.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain Ribosomal_S3_C PF00189.15 EER26270.1 - 1.3e-16 60.5 0.1 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EER26270.1 - 2.6e-12 46.1 0.1 4.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EER26270.1 - 0.058 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Myotub-related PF06602.9 EER26271.1 - 2.4e-123 411.4 0.0 3.4e-123 410.9 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EER26271.1 - 0.0003 21.0 0.2 0.11 12.7 0.0 2.4 2 0 0 2 2 2 2 Tyrosine phosphatase family HD_assoc PF13286.1 EER26271.1 - 0.017 15.3 0.1 0.04 14.1 0.1 1.6 1 1 0 1 1 1 0 Phosphohydrolase-associated domain Y_phosphatase PF00102.22 EER26271.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase SLS PF14611.1 EER26272.1 - 3.3e-52 176.9 0.0 4.7e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator NT-C2 PF10358.4 EER26273.1 - 7.8e-31 106.4 0.0 1e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Snapin_Pallidin PF14712.1 EER26274.1 - 0.035 14.3 5.2 0.052 13.8 3.6 1.3 1 0 0 1 1 1 0 Snapin/Pallidin DUF4140 PF13600.1 EER26274.1 - 0.076 13.4 0.9 0.12 12.8 0.6 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EER26274.1 - 0.18 10.7 5.7 0.24 10.4 4.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EER26274.1 - 0.2 11.7 7.9 0.28 11.2 5.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain PRKCSH-like PF12999.2 EER26274.1 - 0.27 10.8 2.1 0.35 10.4 1.4 1.1 1 0 0 1 1 1 0 Glucosidase II beta subunit-like DUF2992 PF11208.3 EER26274.1 - 0.49 10.2 10.5 0.61 9.9 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Cortex-I_coil PF09304.5 EER26274.1 - 0.68 9.9 10.7 0.98 9.4 7.4 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil TMPIT PF07851.8 EER26274.1 - 0.77 8.7 5.5 0.92 8.5 3.8 1.0 1 0 0 1 1 1 0 TMPIT-like protein PaaA_PaaC PF05138.7 EER26275.1 - 0.12 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Phenylacetic acid catabolic protein DUF3074 PF11274.3 EER26276.1 - 1.3e-53 181.3 0.3 2.7e-53 180.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) FlaC_arch PF05377.6 EER26276.1 - 1.1 9.2 7.4 1.6 8.6 0.6 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EER26276.1 - 4.3 7.1 21.9 0.41 10.5 11.6 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NAM-associated PF14303.1 EER26276.1 - 6.1 7.1 20.9 0.91 9.8 8.9 2.4 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Mnd1 PF03962.10 EER26276.1 - 7.8 6.1 15.8 7.2 6.2 9.7 1.9 1 1 0 1 1 1 0 Mnd1 family SF3b10 PF07189.6 EER26277.1 - 4.2e-36 122.6 0.0 4.6e-36 122.4 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) A_deamin PF02137.13 EER26278.1 - 1.7e-44 152.5 0.0 8.4e-44 150.2 0.0 2.1 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain ERG4_ERG24 PF01222.12 EER26279.1 - 1.1e-146 488.7 3.2 1.3e-146 488.5 2.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EER26279.1 - 0.0014 18.0 0.1 0.0033 16.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Kdo PF06293.9 EER26280.1 - 6.8e-05 22.0 0.0 0.00017 20.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EER26280.1 - 0.014 15.1 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) APH PF01636.18 EER26280.1 - 0.019 14.6 0.0 0.019 14.6 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family ApoO PF09769.4 EER26280.1 - 0.081 12.6 0.6 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 Apolipoprotein O WD40 PF00400.27 EER26281.1 - 2.7e-06 27.0 6.5 6.5e-06 25.8 0.2 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF3954 PF13128.1 EER26281.1 - 0.035 13.5 0.0 0.097 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) APH PF01636.18 EER26282.1 - 1.8e-11 44.2 0.0 5.9e-11 42.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family CIMR PF00878.13 EER26283.1 - 1.3e-06 28.2 0.0 0.002 17.9 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Fungal_trans PF04082.13 EER26284.1 - 4.6e-22 78.1 0.0 9.1e-22 77.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26284.1 - 6.7e-09 35.5 10.4 1.1e-08 34.8 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 EER26285.1 - 1.4e-93 313.1 0.0 2e-93 312.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EER26285.1 - 1.2e-58 198.3 0.9 7.8e-58 195.6 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EER26285.1 - 4.6e-14 52.1 0.0 9.4e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Pro-kuma_activ PF09286.6 EER26286.1 - 3.8e-35 121.0 0.1 8.5e-35 119.8 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EER26286.1 - 4e-10 39.3 0.0 6.3e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Subtilase family EBP PF05241.7 EER26287.1 - 2.2e-05 23.5 5.8 0.00013 21.0 3.7 2.3 1 1 0 1 1 1 1 Emopamil binding protein Zn_clus PF00172.13 EER26288.1 - 0.001 18.9 12.1 0.0019 18.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Scs3p PF10261.4 EER26289.1 - 4.4e-63 212.5 2.0 5.2e-63 212.2 1.4 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Erythro_esteras PF05139.9 EER26291.1 - 2.8e-144 480.6 1.9 3.2e-144 480.3 1.3 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF399 PF04187.8 EER26291.1 - 0.0023 17.4 0.3 0.2 11.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function, DUF399 DUF3535 PF12054.3 EER26293.1 - 1.4e-147 491.9 0.1 1.1e-146 488.9 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EER26293.1 - 1.3e-71 240.9 0.0 9.8e-71 237.9 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER26293.1 - 6.2e-15 54.8 0.0 1.6e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EER26293.1 - 1.4e-14 52.7 7.9 0.22 11.7 0.0 9.9 9 0 0 9 9 9 4 HEAT repeat Vac14_Fab1_bd PF12755.2 EER26293.1 - 9.5e-07 29.1 0.1 0.27 11.6 0.0 4.3 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EER26293.1 - 1e-06 28.8 13.7 0.015 15.5 0.0 7.4 7 2 1 8 8 8 1 HEAT repeats HEAT_EZ PF13513.1 EER26293.1 - 4.1e-06 27.0 12.3 0.67 10.5 0.0 8.0 7 0 0 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 EER26293.1 - 0.00015 21.1 0.0 0.0094 15.3 0.0 3.3 2 1 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.2 EER26293.1 - 0.12 12.1 3.0 14 5.4 0.1 4.9 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Ndufs5 PF10200.4 EER26294.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa CHCH PF06747.8 EER26294.1 - 0.017 14.9 0.2 0.2 11.6 0.1 2.1 1 1 1 2 2 2 0 CHCH domain Sec39 PF08314.6 EER26295.1 - 7.1e-198 658.9 0.0 8.1e-198 658.7 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 MbeD_MobD PF04899.7 EER26295.1 - 0.03 14.2 1.8 0.036 13.9 0.1 2.0 2 0 0 2 2 2 0 MbeD/MobD like Pkinase PF00069.20 EER26296.1 - 8.8e-61 205.3 0.0 1.1e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26296.1 - 1.4e-35 122.6 0.0 2e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26296.1 - 2.8e-08 33.1 0.0 4.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Protoglobin PF11563.3 EER26297.1 - 1.1e-49 168.1 0.0 1.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Protoglobin CDC24 PF06395.6 EER26300.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 1 0 1 1 1 0 CDC24 Calponin Methyltransf_23 PF13489.1 EER26301.1 - 2.2e-21 76.2 0.0 3.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER26301.1 - 1.1e-09 38.6 0.0 2.3e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER26301.1 - 1.7e-08 34.2 0.0 9.7e-08 31.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER26301.1 - 8e-08 32.8 0.0 1.1e-06 29.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER26301.1 - 2.2e-07 31.2 0.0 1.5e-06 28.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER26301.1 - 4.9e-05 23.6 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER26301.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EER26301.1 - 0.0041 16.2 0.0 0.0066 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EER26301.1 - 0.0048 15.9 0.0 0.041 12.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EER26301.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EER26301.1 - 0.0083 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EER26301.1 - 0.015 14.3 0.0 0.16 11.0 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 EER26301.1 - 0.024 14.1 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EER26301.1 - 0.025 14.5 0.1 0.071 13.0 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EER26301.1 - 0.089 12.3 0.0 2.1 7.8 0.0 2.5 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF4451 PF14616.1 EER26302.1 - 2.8e-34 117.5 0.7 4.7e-34 116.8 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Zn_ribbon_recom PF13408.1 EER26302.1 - 0.031 14.5 1.7 0.068 13.4 1.2 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain TPR_11 PF13414.1 EER26303.1 - 1.4e-55 184.8 32.2 3.1e-18 65.1 1.3 6.0 3 3 3 6 6 6 6 TPR repeat TPR_1 PF00515.23 EER26303.1 - 1e-40 135.6 14.9 3.5e-09 35.8 0.1 8.4 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 EER26303.1 - 1.9e-40 133.5 14.3 4e-08 32.5 0.0 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat DnaJ PF00226.26 EER26303.1 - 5.9e-29 99.5 3.3 5.9e-29 99.5 2.3 3.4 4 0 0 4 4 2 1 DnaJ domain TPR_19 PF14559.1 EER26303.1 - 4.4e-28 97.4 14.1 8.6e-06 26.0 0.1 6.1 3 3 3 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EER26303.1 - 3.3e-25 88.1 11.0 3.5e-06 27.5 0.4 5.7 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EER26303.1 - 2.5e-24 83.5 10.4 3.4e-05 24.1 0.0 8.5 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_17 PF13431.1 EER26303.1 - 3.3e-21 73.6 11.2 0.0033 17.5 0.2 7.4 8 0 0 8 8 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 EER26303.1 - 3.5e-21 73.2 7.6 0.00072 19.1 0.1 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EER26303.1 - 1.7e-19 68.0 11.9 0.00043 19.8 0.0 8.0 6 1 2 8 8 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EER26303.1 - 2e-19 69.5 5.2 1.8e-07 31.1 0.1 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EER26303.1 - 6.8e-19 67.5 15.2 3e-06 27.0 0.2 5.6 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.1 EER26303.1 - 3.3e-12 46.0 10.1 0.003 17.3 0.1 5.6 3 2 4 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EER26303.1 - 5.3e-10 39.0 19.3 2.7e-05 24.3 0.0 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_15 PF13429.1 EER26303.1 - 3.9e-09 35.9 6.5 0.012 14.7 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat ChAPs PF09295.5 EER26303.1 - 1.5e-06 27.2 0.3 0.0028 16.4 0.0 2.7 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.12 EER26303.1 - 7.5e-06 26.3 6.4 0.088 13.1 0.2 4.1 3 2 0 3 3 3 2 Bacterial transcriptional activator domain TPR_4 PF07721.9 EER26303.1 - 1.3e-05 25.1 0.5 3.8 8.2 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 EER26303.1 - 1.8e-05 24.7 5.7 3.3 7.8 0.1 4.6 2 2 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EER26303.1 - 3.1e-05 23.7 16.6 0.19 11.7 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EER26303.1 - 0.00018 21.3 9.5 0.44 10.4 0.1 4.9 4 1 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat SHNi-TPR PF10516.4 EER26303.1 - 0.00037 19.6 4.6 0.48 9.7 0.1 4.7 4 0 0 4 4 4 1 SHNi-TPR Alkyl_sulf_dimr PF14863.1 EER26303.1 - 0.0014 18.8 2.1 1.6 8.9 0.2 3.8 2 1 1 3 3 3 1 Alkyl sulfatase dimerisation Coatomer_E PF04733.9 EER26303.1 - 0.03 13.5 1.2 5.7 6.0 0.0 2.9 2 1 0 3 3 3 0 Coatomer epsilon subunit DUF3808 PF10300.4 EER26303.1 - 0.035 12.6 0.1 0.37 9.2 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) RPT PF13446.1 EER26303.1 - 0.042 13.2 0.5 2.7 7.4 0.0 3.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein MIT PF04212.13 EER26303.1 - 0.092 12.6 10.0 21 5.0 0.1 5.1 3 1 2 5 5 4 0 MIT (microtubule interacting and transport) domain DUF3235 PF11574.3 EER26303.1 - 0.27 11.4 3.0 1.1 9.4 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) HHH_8 PF14716.1 EER26303.1 - 0.87 9.8 5.7 32 4.7 0.1 4.2 4 0 0 4 4 3 0 Helix-hairpin-helix domain DUF4098 PF13345.1 EER26304.1 - 0.00043 20.1 3.2 0.021 14.7 0.0 3.8 3 1 0 3 3 3 1 Domain of unknown function (DUF4098) DUF2763 PF10961.3 EER26304.1 - 0.082 13.3 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) HC2 PF07382.6 EER26305.1 - 0.0019 18.1 53.6 0.0035 17.2 37.2 1.4 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 MFS_1 PF07690.11 EER26306.1 - 4.3e-27 94.7 58.5 1.5e-23 83.1 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Spore_III_AE PF09546.5 EER26306.1 - 0.0041 16.1 3.1 0.009 15.0 2.1 1.5 1 0 0 1 1 1 1 Stage III sporulation protein AE (spore_III_AE) Pkinase PF00069.20 EER26307.1 - 5.3e-38 130.6 0.0 8e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26307.1 - 2.1e-29 102.3 0.0 2.8e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26307.1 - 0.0014 17.6 0.0 0.0035 16.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Med10 PF09748.4 EER26308.1 - 5.3e-45 152.3 0.1 6.2e-45 152.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EER26308.1 - 0.007 15.9 0.1 0.017 14.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function, E. rectale Gene description (DUF3877) NPV_P10 PF05531.7 EER26308.1 - 0.028 14.6 0.0 0.077 13.2 0.0 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Peptidase_M28 PF04389.12 EER26310.1 - 3.9e-30 104.9 0.0 6.2e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PTP_N PF12453.3 EER26310.1 - 6.7 6.4 6.2 2.2 7.9 0.2 3.1 3 0 0 3 3 3 0 Protein tyrosine phosphatase N terminal F-box-like PF12937.2 EER26311.1 - 3e-12 46.0 1.4 5.8e-12 45.1 0.4 2.0 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EER26311.1 - 1.3e-09 37.6 15.3 0.12 12.1 0.0 6.6 3 1 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.2 EER26311.1 - 1.5e-09 37.2 7.6 0.11 12.0 0.0 7.4 5 2 2 9 9 9 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EER26311.1 - 4.3e-09 35.5 15.5 2.2 8.5 0.0 10.8 14 0 0 14 14 14 3 Leucine Rich repeat F-box PF00646.28 EER26311.1 - 2.2e-05 23.9 4.7 5.8e-05 22.6 0.3 3.6 3 0 0 3 3 3 1 F-box domain DUF1699 PF08004.6 EER26311.1 - 0.0044 16.5 1.0 0.13 11.7 0.1 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF1699) Adeno_E4_34 PF04528.8 EER26311.1 - 0.015 14.8 7.3 0.2 11.2 1.9 2.9 2 0 0 2 2 2 0 Adenovirus early E4 34 kDa protein conserved region AMP-binding PF00501.23 EER26312.1 - 1.7e-70 237.5 0.0 2e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER26312.1 - 1.5e-13 51.4 0.1 3.4e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_L13 PF00572.13 EER26313.1 - 7.3e-28 97.1 0.1 1.4e-27 96.2 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 Metallophos PF00149.23 EER26314.1 - 2.4e-11 43.3 0.5 6.4e-11 42.0 0.4 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER26314.1 - 6.2e-09 35.8 0.0 1.1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EER26314.1 - 0.087 11.9 0.0 0.3 10.1 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily DnaJ PF00226.26 EER26315.1 - 8.8e-24 83.0 2.0 1.7e-23 82.0 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4470 PF14737.1 EER26316.1 - 9.1e-24 83.1 0.0 1.6e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EER26316.1 - 3.2e-08 33.2 12.1 7.9e-08 32.0 8.4 1.7 1 0 0 1 1 1 1 MYND finger APH PF01636.18 EER26317.1 - 4e-13 49.6 0.2 1.5e-12 47.7 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER26317.1 - 0.0011 18.5 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EER26317.1 - 0.0015 17.8 0.0 0.0061 15.9 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EER26317.1 - 0.044 12.9 0.0 0.97 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein kinase domain DUF1679 PF07914.6 EER26317.1 - 0.14 10.7 0.0 2.4 6.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pkinase PF00069.20 EER26318.1 - 1.2e-06 27.8 0.0 1.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Nuc_sug_transp PF04142.10 EER26319.1 - 8.8e-08 31.5 0.3 1.4e-07 30.9 0.2 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EER26319.1 - 4.2e-07 29.1 5.5 8.4e-07 28.1 3.8 1.4 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EER26319.1 - 1.4e-06 28.3 21.7 0.0012 18.8 3.1 3.3 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EER26319.1 - 0.0014 18.3 13.5 0.024 14.2 0.3 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EER26319.1 - 0.009 16.2 6.4 0.009 16.2 4.4 3.5 2 1 1 3 3 3 1 Multidrug resistance efflux transporter MerC PF03203.9 EER26319.1 - 1.1 9.6 13.3 0.12 12.7 1.9 3.7 4 1 0 4 4 4 0 MerC mercury resistance protein TrbC PF04956.8 EER26319.1 - 2.3 8.3 12.4 0.49 10.4 1.5 3.2 3 0 0 3 3 3 0 TrbC/VIRB2 family Beta-lactamase PF00144.19 EER26320.1 - 3.4e-50 170.9 0.0 8.5e-49 166.3 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase DUF3671 PF12420.3 EER26321.1 - 0.065 13.2 0.5 1.4 8.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function Fumarate_red_D PF02313.12 EER26321.1 - 2.5 8.0 12.1 0.075 12.9 3.2 2.2 2 1 1 3 3 3 0 Fumarate reductase subunit D Adaptin_N PF01602.15 EER26322.1 - 2e-140 468.5 0.5 2.4e-140 468.3 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EER26322.1 - 6.6e-20 71.5 0.0 1.6e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EER26322.1 - 1.1e-05 25.5 1.9 0.034 14.4 0.0 4.0 3 2 1 4 4 4 2 HEAT repeats TIP120 PF08623.5 EER26322.1 - 0.0051 16.4 0.5 0.019 14.5 0.1 2.1 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EER26322.1 - 0.019 15.0 1.4 75 3.8 0.0 4.8 4 1 0 4 4 4 0 HEAT repeat Cnd1 PF12717.2 EER26322.1 - 0.35 10.7 7.5 0.065 13.0 0.2 3.4 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Spc97_Spc98 PF04130.8 EER26323.1 - 9.8e-117 390.5 0.0 1.3e-116 390.0 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family FSA_C PF10479.4 EER26323.1 - 0.26 9.2 0.0 0.39 8.7 0.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF2373 PF10180.4 EER26324.1 - 2e-19 68.8 0.0 3.7e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Proteasome PF00227.21 EER26325.1 - 2.9e-49 166.9 0.0 3.9e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EER26325.1 - 4.8e-13 48.1 0.3 9e-13 47.2 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature PTR2 PF00854.16 EER26327.1 - 1.3e-54 185.4 14.0 2.4e-53 181.2 9.7 2.2 1 1 0 1 1 1 1 POT family Glyco_hydro_18 PF00704.23 EER26328.1 - 9.6e-88 294.8 0.8 1.1e-87 294.6 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ubiquitin PF00240.18 EER26329.1 - 1.5e-34 117.1 1.1 2.8e-34 116.3 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EER26329.1 - 1.8e-27 94.8 2.2 3.7e-27 93.8 1.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EER26329.1 - 7e-20 70.4 0.8 1.4e-19 69.5 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EER26329.1 - 9.1e-06 25.8 0.2 4.3e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EER26329.1 - 0.00018 21.2 0.1 0.0003 20.5 0.0 1.4 1 1 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EER26329.1 - 0.0008 19.2 0.9 0.0017 18.2 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EER26329.1 - 0.004 17.3 0.6 0.0054 16.8 0.4 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF971 PF06155.7 EER26329.1 - 0.0041 17.5 0.1 0.007 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF2870 PF11069.3 EER26329.1 - 0.035 14.1 0.3 0.088 12.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) IBR PF01485.16 EER26329.1 - 0.059 13.2 0.5 0.094 12.5 0.4 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 EER26329.1 - 0.097 10.9 3.0 0.97 7.6 0.1 2.0 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain zf-H2C2_2 PF13465.1 EER26330.1 - 1.6e-09 37.6 12.9 3e-05 24.0 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EER26330.1 - 2.3e-07 30.7 21.3 0.031 14.6 5.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER26330.1 - 0.0001 22.3 17.4 0.028 14.7 0.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EER26330.1 - 7.7 6.5 12.9 0.11 12.4 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger DUF155 PF02582.9 EER26331.1 - 6.1e-42 143.4 0.0 8.7e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Clathrin PF00637.15 EER26332.1 - 2.1e-19 69.5 1.6 5.3e-17 61.7 0.0 3.7 4 0 0 4 4 4 1 Region in Clathrin and VPS WD40 PF00400.27 EER26332.1 - 0.001 18.8 5.8 0.63 10.0 1.9 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat PQQ_3 PF13570.1 EER26332.1 - 0.0079 16.4 1.1 0.025 14.8 0.2 2.4 2 0 0 2 2 2 1 PQQ-like domain zf-RING_5 PF14634.1 EER26332.1 - 0.032 13.9 0.5 0.088 12.5 0.4 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 EER26332.1 - 0.11 12.3 1.5 0.31 10.9 1.0 1.8 1 0 0 1 1 1 0 Ring finger domain TRAP_alpha PF03896.11 EER26332.1 - 0.29 10.1 5.8 0.56 9.1 4.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 EER26332.1 - 0.53 8.7 17.8 0.95 7.8 12.3 1.3 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EER26332.1 - 1.3 9.3 16.8 4 7.7 11.6 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain VID27 PF08553.5 EER26332.1 - 2.3 6.3 9.7 3.5 5.7 6.7 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein FAM176 PF14851.1 EER26332.1 - 3.4 7.3 8.5 8.6 6.0 5.9 1.6 1 0 0 1 1 1 0 FAM176 family Myc_N PF01056.13 EER26332.1 - 4.4 6.3 12.3 9.8 5.2 8.5 1.5 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.6 EER26332.1 - 4.7 6.9 9.4 10 5.9 6.5 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FYDLN_acid PF09538.5 EER26332.1 - 9.3 6.8 24.3 4.3 7.9 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (FYDLN_acid) CP2 PF04516.10 EER26334.1 - 1.9e-84 282.4 0.0 2.9e-84 281.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor TraQ PF09679.5 EER26335.1 - 0.42 10.5 1.8 0.49 10.3 0.1 1.8 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) Metallopep PF12044.3 EER26336.1 - 2.9e-145 483.9 0.0 3.8e-145 483.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family GST_C_2 PF13410.1 EER26338.1 - 1.3e-06 28.1 2.8 1.3e-06 28.1 0.6 2.0 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EER26338.1 - 0.00033 20.5 0.0 0.00077 19.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EER26338.1 - 0.0012 19.0 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DJ-1_PfpI PF01965.19 EER26339.1 - 8.9e-23 80.3 0.2 1.9e-22 79.2 0.1 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EER26339.1 - 0.0036 16.7 0.0 0.0077 15.7 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DNA_ligase_A_M PF01068.16 EER26340.1 - 4.2e-51 173.1 0.0 1.6e-48 164.7 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EER26340.1 - 2.3e-41 141.5 0.0 4.5e-41 140.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EER26340.1 - 9.8e-22 77.1 0.0 3.4e-21 75.4 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region HTH_15 PF12324.3 EER26340.1 - 0.15 11.6 0.1 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase RINT1_TIP1 PF04437.8 EER26341.1 - 1.5e-167 558.1 0.0 1.5e-167 558.1 0.0 2.3 2 1 0 2 2 2 1 RINT-1 / TIP-1 family TPR_11 PF13414.1 EER26341.1 - 0.076 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 TPR repeat APG6 PF04111.7 EER26341.1 - 0.98 8.4 10.0 2 7.3 6.9 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Pyridoxal_deC PF00282.14 EER26342.1 - 8.4e-81 271.2 0.0 1e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EER26342.1 - 2.9e-08 33.1 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EER26342.1 - 1.5e-06 27.2 0.0 2.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V PUF PF00806.14 EER26343.1 - 1.1e-16 59.2 0.0 0.32 10.5 0.0 7.4 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat ABA_GPCR PF12430.3 EER26343.1 - 0.067 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor PurA PF04845.8 EER26343.1 - 0.073 12.1 0.1 0.53 9.3 0.0 2.1 2 0 0 2 2 2 0 PurA ssDNA and RNA-binding protein Y_phosphatase PF00102.22 EER26344.1 - 4e-51 173.6 0.0 9.5e-51 172.3 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EER26344.1 - 0.0022 18.0 0.0 0.0069 16.4 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EER26344.1 - 0.0027 17.2 0.1 0.0089 15.6 0.0 1.8 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EER26344.1 - 0.0032 17.7 0.1 0.012 15.9 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family VanZ PF04892.7 EER26345.1 - 8.2e-12 45.2 0.1 1.1e-11 44.7 0.1 1.2 1 0 0 1 1 1 1 VanZ like family DUF4131 PF13567.1 EER26345.1 - 5.9 6.2 6.5 64 2.8 2.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Bromodomain PF00439.20 EER26346.1 - 1.7e-20 72.6 2.1 7.9e-20 70.5 0.1 2.7 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 EER26346.1 - 6.3e-09 35.4 0.0 2.1e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Bromodomain associated Piwi PF02171.12 EER26347.1 - 6.5e-70 235.4 0.0 8.9e-70 235.0 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EER26347.1 - 1.1e-17 63.0 0.0 2.7e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EER26347.1 - 2e-14 53.0 0.8 3.5e-14 52.2 0.6 1.4 1 0 0 1 1 1 1 PAZ domain Suf PF05843.9 EER26348.1 - 1e-90 304.2 0.0 1e-90 304.2 0.0 4.0 5 2 1 6 6 6 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EER26348.1 - 1.9e-07 31.0 0.1 0.06 14.0 0.0 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EER26348.1 - 0.00074 19.8 0.2 4.5 7.6 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER26348.1 - 0.0022 18.6 0.3 2 9.1 0.0 3.9 3 1 0 4 4 4 1 Tetratricopeptide repeat HAT PF02184.11 EER26348.1 - 0.01 15.5 0.3 0.01 15.5 0.2 2.5 3 0 0 3 3 3 0 HAT (Half-A-TPR) repeat ASF1_hist_chap PF04729.8 EER26349.1 - 3.4e-68 228.1 0.0 4.5e-68 227.7 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 EER26349.1 - 9.9 3.9 19.0 13 3.5 13.1 1.1 1 0 0 1 1 1 0 Nop14-like family Lgl_C PF08596.5 EER26350.1 - 5.2e-122 407.1 0.0 8.5e-122 406.4 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EER26350.1 - 0.0022 17.7 5.8 0.13 12.2 0.2 5.3 6 0 0 6 6 6 1 WD domain, G-beta repeat GMC_oxred_C PF05199.8 EER26350.1 - 0.087 13.1 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 GMC oxidoreductase APH PF01636.18 EER26351.1 - 2.1e-06 27.6 0.0 2.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.12 EER26352.1 - 3.1e-12 46.5 0.0 5.8e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 THUMP domain TPP_enzyme_N PF02776.13 EER26353.1 - 1.8e-34 118.7 0.0 2.9e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EER26353.1 - 5.6e-25 87.6 0.0 1.2e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EER26353.1 - 1.4e-16 60.3 0.0 3.3e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EER26353.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Pkinase PF00069.20 EER26354.1 - 2.7e-63 213.5 0.0 4.1e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26354.1 - 4.9e-45 153.6 0.0 7.8e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26354.1 - 7.5e-14 51.3 0.0 2.4e-10 39.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EER26354.1 - 0.0089 15.1 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sec34 PF04136.10 EER26355.1 - 2.7e-29 101.8 0.4 6.9e-29 100.5 0.2 1.7 1 0 0 1 1 1 1 Sec34-like family SYCE1 PF15233.1 EER26355.1 - 0.067 13.1 0.2 3.6 7.5 0.1 2.6 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 ApoLp-III PF07464.6 EER26355.1 - 0.27 11.2 1.2 0.98 9.4 0.0 2.5 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Mid2 PF04478.7 EER26356.1 - 1.4e-07 31.0 0.0 1.4e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Syndecan PF01034.15 EER26356.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 EER26356.1 - 0.031 13.0 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Rod_cone_degen PF15201.1 EER26356.1 - 0.054 13.3 3.0 0.06 13.2 0.0 2.6 2 0 0 2 2 2 0 Progressive rod-cone degeneration SpoIIIAH PF12685.2 EER26356.1 - 0.092 12.2 1.1 0.35 10.3 0.5 1.9 2 0 0 2 2 2 0 SpoIIIAH-like protein SKG6 PF08693.5 EER26356.1 - 0.11 11.7 0.4 0.11 11.7 0.3 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CRA PF06589.6 EER26356.1 - 0.12 11.6 1.4 2.9 7.1 0.0 2.6 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Tad PF13400.1 EER26356.1 - 1 9.4 5.8 0.67 10.0 0.6 2.2 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Plasmodium_Vir PF05795.6 EER26356.1 - 1.2 8.2 3.1 2.9 7.0 2.1 1.6 1 1 0 1 1 1 0 Plasmodium vivax Vir protein VPEP PF07589.6 EER26356.1 - 5.3 7.0 11.8 7.5 6.6 1.1 2.7 2 0 0 2 2 2 0 PEP-CTERM motif DUF2946 PF11162.3 EER26356.1 - 5.8 7.1 9.7 0.94 9.6 3.0 2.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2946) TMEM154 PF15102.1 EER26356.1 - 6.8 6.3 10.6 11 5.6 3.8 3.0 1 1 1 2 2 2 0 TMEM154 protein family Pex14_N PF04695.8 EER26356.1 - 7.3 6.6 15.0 30 4.6 9.0 2.7 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 EER26357.1 - 3.2e-11 42.8 0.0 4.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EER26357.1 - 3.8e-07 30.0 0.5 2e-05 24.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EER26357.1 - 9.4e-07 28.1 0.0 1.7e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26357.1 - 0.00097 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EER26357.1 - 0.0035 16.4 0.0 0.0053 15.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EER26357.1 - 0.0083 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EER26357.1 - 0.011 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF3508 PF12018.3 EER26358.1 - 0.083 11.8 0.3 0.11 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Imm43 PF15602.1 EER26358.1 - 0.1 12.5 1.7 0.4 10.6 0.2 2.2 1 1 1 2 2 2 0 Immunity protein 43 FUSC PF04632.7 EER26358.1 - 0.51 8.7 4.5 0.59 8.5 3.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pex19 PF04614.7 EER26359.1 - 7.6e-45 153.4 12.0 7.6e-45 153.4 8.3 1.8 1 1 1 2 2 2 1 Pex19 protein family Flu_M1_C PF08289.6 EER26359.1 - 0.35 10.9 2.2 1.1 9.2 1.6 1.8 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF937 PF06078.6 EER26359.1 - 0.8 9.9 9.5 32 4.7 7.4 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF937) Cu_amine_oxid PF01179.15 EER26360.1 - 8.4e-167 555.0 0.0 1e-166 554.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EER26360.1 - 1.4e-09 37.9 0.2 2.6e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EER26360.1 - 8.6e-09 35.3 0.0 2.1e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain bZIP_1 PF00170.16 EER26361.1 - 2.2e-05 24.3 9.1 3.6e-05 23.6 6.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor rRNA_processing PF08524.6 EER26361.1 - 0.031 14.0 2.9 0.047 13.4 2.0 1.2 1 0 0 1 1 1 0 rRNA processing DUF4407 PF14362.1 EER26361.1 - 0.071 12.0 1.0 0.097 11.6 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GvpL_GvpF PF06386.6 EER26361.1 - 0.19 11.3 2.8 0.31 10.5 1.9 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.10 EER26361.1 - 1.9 8.3 13.0 0.23 11.2 6.1 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Stm1_N PF09598.5 EER26362.1 - 2.8e-17 63.1 1.3 2.8e-17 63.1 0.9 4.0 3 1 0 3 3 3 1 Stm1 DUF1793 PF08760.6 EER26363.1 - 8.4e-71 237.3 0.2 1.4e-70 236.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) tRNA-synt_1c PF00749.16 EER26364.1 - 1.8e-102 342.2 0.0 2.5e-102 341.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EER26364.1 - 1.1e-40 139.1 0.3 2.2e-40 138.1 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EER26364.1 - 1.2e-07 32.0 0.0 3.9e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EER26364.1 - 0.0012 18.8 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EER26364.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EER26364.1 - 0.011 14.9 0.6 0.029 13.5 0.5 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DEAD PF00270.24 EER26367.1 - 2.4e-39 134.5 0.0 3.7e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER26367.1 - 7.4e-27 93.0 0.1 2.2e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EER26367.1 - 9.6e-05 21.3 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EER26367.1 - 0.00052 19.9 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HCO3_cotransp PF00955.16 EER26368.1 - 2.5e-70 237.6 14.1 1e-41 143.2 3.1 2.0 1 1 1 2 2 2 2 HCO3- transporter family zf-CCHC PF00098.18 EER26369.1 - 3.3e-11 42.5 10.0 3.8e-05 23.4 2.1 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EER26369.1 - 5.1e-09 35.6 0.2 9.5e-09 34.7 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EER26369.1 - 2.1e-06 27.3 6.3 0.00069 19.2 1.9 2.6 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EER26369.1 - 6.3e-06 25.7 0.2 1.5e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EER26369.1 - 0.00037 20.0 6.2 0.15 11.7 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EER26369.1 - 0.02 14.5 10.7 0.42 10.3 0.4 2.9 3 0 0 3 3 3 0 Zinc knuckle eIF3g PF12353.3 EER26369.1 - 4.3 7.2 8.4 37 4.2 3.3 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G GST_N_3 PF13417.1 EER26370.1 - 1.7e-14 53.7 0.0 3.1e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EER26370.1 - 1.6e-12 47.2 0.0 2.8e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EER26370.1 - 2.9e-11 43.3 0.0 6.1e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER26370.1 - 3.6e-11 42.7 0.0 8e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EER26370.1 - 2.4e-10 40.2 0.0 4.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EER26370.1 - 4.1e-09 36.8 0.3 2.3e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain NAD_binding_6 PF08030.7 EER26371.1 - 1.3e-21 77.1 0.0 2e-19 70.0 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EER26371.1 - 7e-16 58.4 10.6 7e-16 58.4 7.4 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EER26371.1 - 9.6e-16 57.5 0.0 7.8e-15 54.6 0.0 2.4 2 1 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EER26371.1 - 0.085 13.4 0.0 0.16 12.5 0.0 1.5 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EER26371.1 - 5.7 7.1 16.7 0.11 12.5 0.9 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) CLU PF13236.1 EER26373.1 - 9.7e-79 263.8 0.0 1.5e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EER26373.1 - 4.5e-55 186.1 0.3 1.3e-54 184.6 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EER26373.1 - 2e-25 88.7 0.5 4.9e-25 87.4 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EER26373.1 - 9.3e-24 83.1 4.3 9.4e-10 38.3 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EER26373.1 - 4.1e-16 58.3 0.0 0.0014 18.5 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EER26373.1 - 2.2e-05 24.0 1.2 0.51 10.0 0.0 3.7 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EER26373.1 - 0.00051 19.7 1.9 0.13 12.2 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EER26373.1 - 0.0027 18.3 0.0 3.9 8.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EER26373.1 - 0.0028 17.3 1.4 0.53 10.1 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat EnY2 PF10163.4 EER26373.1 - 0.041 13.8 0.2 0.24 11.3 0.1 2.3 1 0 0 1 1 1 0 Transcription factor e(y)2 DUF727 PF05303.7 EER26373.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF727) TPR_17 PF13431.1 EER26373.1 - 0.32 11.2 2.3 40 4.7 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 EER26374.1 - 8.4e-06 25.6 0.1 1.5e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EER26374.1 - 2e-05 24.6 1.8 0.00039 20.4 0.8 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EER26374.1 - 0.0053 15.7 0.0 0.0098 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 EER26374.1 - 0.0054 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EER26374.1 - 0.019 15.1 0.5 0.22 11.6 0.2 2.5 1 1 1 2 2 2 0 AAA domain Miro PF08477.8 EER26374.1 - 0.023 15.2 0.4 1.3 9.4 0.0 2.6 1 1 1 2 2 2 0 Miro-like protein AAA_25 PF13481.1 EER26374.1 - 0.027 13.8 0.7 0.064 12.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EER26374.1 - 0.058 13.1 0.0 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Ras PF00071.17 EER26376.1 - 1.8e-56 189.9 0.0 2.2e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER26376.1 - 1.3e-20 74.0 0.0 1.9e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER26376.1 - 7.7e-14 51.3 0.0 1.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER26376.1 - 9.5e-06 24.9 0.0 1.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EER26376.1 - 3.2e-05 23.4 0.0 8.2e-05 22.1 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EER26376.1 - 0.00019 21.3 0.0 0.00031 20.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EER26376.1 - 0.015 15.3 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EER26376.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EER26376.1 - 0.13 11.4 0.1 0.41 9.8 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 XFP_N PF09364.5 EER26377.1 - 1.1e-153 511.2 0.0 1.5e-153 510.9 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 EER26377.1 - 3.6e-66 222.4 0.0 5.7e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 EER26377.1 - 6.8e-65 217.9 0.0 1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 EER26377.1 - 0.0014 18.2 0.2 0.003 17.1 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Acetate_kinase PF00871.12 EER26378.1 - 4e-90 302.1 0.0 4.7e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Ribosomal_S7e PF01251.13 EER26379.1 - 9.4e-81 269.8 0.1 1e-80 269.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 EER26380.1 - 2.8e-120 402.3 0.0 3.4e-120 402.0 0.0 1.0 1 0 0 1 1 1 1 Dynactin p62 family Methyltransf_23 PF13489.1 EER26381.1 - 2.4e-08 33.8 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER26381.1 - 7.6e-08 32.7 0.0 1.8e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER26381.1 - 3.9e-05 24.0 0.0 9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER26381.1 - 0.0016 18.0 0.0 0.0044 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain P16-Arc PF04699.9 EER26382.1 - 4.1e-58 195.7 0.0 4.8e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Secretin_N PF03958.12 EER26382.1 - 0.18 12.0 1.2 1.7 8.8 0.1 2.2 1 1 1 2 2 2 0 Bacterial type II/III secretion system short domain E1-E2_ATPase PF00122.15 EER26383.1 - 1.2e-58 197.8 0.2 2.4e-58 196.9 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EER26383.1 - 3.6e-46 157.0 8.2 3.6e-46 157.0 5.7 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EER26383.1 - 1.1e-26 94.6 0.0 2.6e-26 93.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER26383.1 - 2.4e-18 65.8 0.0 5.2e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EER26383.1 - 1.7e-13 51.1 0.0 5.7e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EER26383.1 - 3.5e-07 29.5 0.4 1.3e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EER26383.1 - 0.00012 21.8 0.0 0.003 17.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EER26383.1 - 0.035 14.0 0.0 0.035 14.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) WD40 PF00400.27 EER26384.1 - 4.5e-42 140.4 7.7 1.3e-09 37.5 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EER26384.1 - 4.4e-10 39.1 0.2 8.5e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER26384.1 - 0.0001 21.8 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ PF01011.16 EER26384.1 - 0.00019 20.7 0.1 0.88 9.2 0.0 3.4 3 0 0 3 3 3 2 PQQ enzyme repeat PQQ_2 PF13360.1 EER26384.1 - 0.00041 19.8 0.3 0.014 14.8 0.1 2.5 2 1 1 3 3 3 1 PQQ-like domain Peptidase_S8 PF00082.17 EER26385.1 - 9.4e-40 136.5 7.9 1.3e-39 136.0 5.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER26385.1 - 1.6e-12 47.8 0.0 3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF4126 PF13548.1 EER26385.1 - 0.0033 16.8 1.0 0.0074 15.7 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4126) EB1 PF03271.12 EER26386.1 - 6.5e-17 61.2 1.4 9.3e-17 60.8 0.5 1.7 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.26 EER26386.1 - 9e-07 28.9 0.2 1.6e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.11 EER26386.1 - 0.0025 16.0 0.0 0.0039 15.4 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus UL6 like Adeno_E3_CR2 PF02439.10 EER26387.1 - 0.045 13.3 0.1 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF2370 PF10176.4 EER26388.1 - 0.0024 17.2 5.3 0.0044 16.3 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) PHD PF00628.24 EER26389.1 - 2.9e-09 36.4 10.6 5.7e-09 35.5 7.3 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EER26389.1 - 2.3e-08 34.2 0.0 5.2e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Fork_head PF00250.13 EER26391.1 - 2.1e-36 123.8 2.2 3.7e-36 123.0 1.5 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EER26391.1 - 8.7e-09 35.3 0.0 1.6e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-C2H2 PF00096.21 EER26392.1 - 1.2e-05 25.3 17.1 3.5e-05 23.8 1.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER26392.1 - 2.2e-05 24.4 3.3 2.2e-05 24.4 2.3 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EER26392.1 - 0.0018 18.3 0.7 0.004 17.2 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EER26392.1 - 0.0018 18.4 0.7 0.0018 18.4 0.5 3.2 3 0 0 3 3 3 1 C2H2-type zinc finger Fungal_trans PF04082.13 EER26393.1 - 3e-29 101.7 0.0 7.3e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26393.1 - 7e-11 41.8 12.4 1.2e-10 41.0 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EER26393.1 - 0.054 13.4 0.2 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Gal4-like dimerisation domain Sugar_tr PF00083.19 EER26394.1 - 4.7e-107 358.3 19.2 5.3e-107 358.1 13.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER26394.1 - 2.2e-20 72.6 30.0 2.2e-20 72.6 20.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EER26395.1 - 5.9e-06 25.1 0.0 1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sigma70_r2 PF04542.9 EER26395.1 - 0.14 11.7 0.2 0.29 10.7 0.2 1.5 1 0 0 1 1 1 0 Sigma-70 region 2 Ric8 PF10165.4 EER26396.1 - 0.01 14.6 1.5 0.014 14.2 1.0 1.1 1 0 0 1 1 1 0 Guanine nucleotide exchange factor synembryn PHD PF00628.24 EER26397.1 - 1.8e-11 43.5 8.9 3.7e-11 42.5 6.2 1.5 1 0 0 1 1 1 1 PHD-finger APH PF01636.18 EER26397.1 - 0.0021 17.8 0.3 0.011 15.4 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER26397.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Med31 PF05669.7 EER26399.1 - 4.8e-30 103.3 0.1 5.8e-30 103.0 0.1 1.1 1 0 0 1 1 1 1 SOH1 Tcf25 PF04910.9 EER26399.1 - 0.008 15.1 0.0 0.0085 15.0 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 HSP20 PF00011.16 EER26400.1 - 3.1e-17 62.3 2.4 4.2e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Xan_ur_permease PF00860.15 EER26401.1 - 9.5e-25 86.8 28.5 1.7e-22 79.4 19.1 3.0 2 1 0 2 2 2 2 Permease family Pal1 PF08316.6 EER26402.1 - 1.6e-47 161.4 1.7 1.8e-45 154.8 1.2 2.7 1 1 0 1 1 1 1 Pal1 cell morphology protein DASH_Dad3 PF08656.5 EER26403.1 - 2.7e-27 94.2 1.6 3.1e-27 94.0 1.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Peptidase_M75 PF09375.5 EER26403.1 - 0.02 14.2 0.1 0.027 13.8 0.1 1.2 1 0 0 1 1 1 0 Imelysin FlgN PF05130.7 EER26403.1 - 0.037 14.2 0.0 0.046 13.9 0.0 1.2 1 0 0 1 1 1 0 FlgN protein Baculo_gp41 PF04700.7 EER26403.1 - 0.12 11.8 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region MAGE PF01454.14 EER26404.1 - 4.9e-40 136.9 0.0 6.5e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 MAGE family DUF4196 PF13846.1 EER26404.1 - 5.4 7.3 8.5 5.2 7.3 3.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4196) Ank_2 PF12796.2 EER26405.1 - 3.5e-11 43.2 0.0 4e-10 39.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EER26405.1 - 5.1e-10 38.6 0.0 1.5e-05 24.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EER26405.1 - 8.3e-10 38.6 0.1 0.00091 19.4 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER26405.1 - 2.6e-09 36.4 0.0 0.0014 18.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EER26405.1 - 1.4e-08 35.0 0.1 0.00014 22.2 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Lipoprotein_19 PF13617.1 EER26405.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.5 1 0 0 1 1 1 0 YnbE-like lipoprotein TFIIS_C PF01096.13 EER26406.1 - 4.8e-19 67.6 2.1 4.8e-19 67.6 1.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EER26406.1 - 1.7e-05 24.3 7.0 7.8e-05 22.2 2.3 3.1 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_ribbon_recom PF13408.1 EER26406.1 - 0.014 15.6 1.4 1.4 9.2 0.2 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain IBR PF01485.16 EER26406.1 - 0.049 13.5 7.9 1.4 8.8 0.2 2.9 2 1 0 2 2 2 0 IBR domain Zn_Tnp_IS1595 PF12760.2 EER26406.1 - 0.17 11.6 6.3 0.33 10.8 0.4 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EER26406.1 - 0.19 11.1 1.1 5.3 6.5 0.0 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 EER26406.1 - 0.28 11.0 6.2 1 9.2 0.2 2.6 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 EER26406.1 - 0.38 10.3 10.0 2 8.0 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EER26406.1 - 0.45 10.2 10.7 2.3 7.9 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EER26406.1 - 0.7 9.7 2.9 0.8 9.5 0.1 2.3 2 1 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF951 PF06107.6 EER26406.1 - 0.78 9.2 2.5 4 7.0 0.0 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) C1_4 PF07975.7 EER26406.1 - 1.5 8.8 4.7 3.9 7.5 0.2 2.8 2 2 0 2 2 2 0 TFIIH C1-like domain Rubredoxin PF00301.15 EER26406.1 - 1.7 8.5 6.4 6.2 6.7 0.2 3.3 3 0 0 3 3 3 0 Rubredoxin TF_Zn_Ribbon PF08271.7 EER26406.1 - 3 7.2 5.7 15 5.0 0.1 2.8 3 0 0 3 3 3 0 TFIIB zinc-binding GTP_EFTU PF00009.22 EER26407.1 - 6.2e-58 195.3 0.0 9.4e-58 194.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EER26407.1 - 1e-36 125.0 0.0 3e-36 123.5 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EER26407.1 - 4.5e-16 58.7 2.4 8e-16 57.9 1.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EER26407.1 - 0.0001 21.8 1.9 0.00013 21.5 0.2 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EER26407.1 - 0.0024 17.7 0.2 0.0075 16.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Chalcone PF02431.10 EER26408.1 - 7.4e-61 205.0 0.0 9.3e-61 204.6 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Glutaredoxin PF00462.19 EER26409.1 - 3.6e-20 71.6 0.0 4.8e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EER26409.1 - 0.0084 16.2 0.2 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 EER26409.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.15 EER26409.1 - 0.034 13.8 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 EER26409.1 - 0.037 13.5 0.2 0.22 11.0 0.2 2.0 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EER26409.1 - 0.058 13.2 0.1 0.11 12.3 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.1 EER26409.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 EER26409.1 - 0.22 11.4 1.6 3.6 7.5 0.3 2.1 1 1 1 2 2 2 0 Thioredoxin Macoilin PF09726.4 EER26410.1 - 0.058 11.6 4.6 0.083 11.1 3.2 1.2 1 0 0 1 1 1 0 Transmembrane protein BAG PF02179.11 EER26411.1 - 3.3e-16 59.1 1.4 7.7e-16 57.9 1.0 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EER26411.1 - 0.00031 20.0 0.2 0.00073 18.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.4 EER26411.1 - 0.1 12.8 0.1 0.27 11.4 0.1 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Anophelin PF10731.4 EER26411.1 - 0.18 11.8 1.8 0.51 10.4 1.2 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito LMBR1 PF04791.11 EER26412.1 - 5.9e-34 117.4 7.7 1.5e-33 116.0 5.4 1.6 1 1 0 1 1 1 1 LMBR1-like membrane protein Med15_fungi PF05397.7 EER26414.1 - 1.1e-28 99.4 0.3 1.1e-28 99.4 0.2 2.9 2 1 1 3 3 3 1 Mediator complex subunit 15 Aft1_HRA PF11786.3 EER26415.1 - 4.3e-26 90.9 11.3 4.3e-26 90.9 7.8 2.8 4 0 0 4 4 4 1 Aft1 HRA domain Aft1_HRR PF11787.3 EER26415.1 - 7.9e-21 74.8 2.3 7.9e-21 74.8 1.6 3.7 2 1 2 4 4 4 1 Aft1 HRR domain Aft1_OSA PF11785.3 EER26415.1 - 6.2e-11 42.6 6.0 6.2e-11 42.6 4.1 3.3 4 0 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 EER26415.1 - 1.5e-05 24.8 2.0 2.3e-05 24.2 1.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor Nnf1 PF03980.9 EER26415.1 - 0.086 12.8 1.2 0.13 12.2 0.8 1.3 1 0 0 1 1 1 0 Nnf1 DivIC PF04977.10 EER26415.1 - 0.2 11.1 0.7 0.33 10.4 0.5 1.3 1 0 0 1 1 1 0 Septum formation initiator CAP_N PF01213.14 EER26416.1 - 0.29 10.3 7.9 0.36 10.0 5.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EER26416.1 - 0.34 10.2 5.1 0.48 9.7 3.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator ArsA_ATPase PF02374.10 EER26417.1 - 3.2e-112 374.5 0.0 3.6e-112 374.3 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EER26417.1 - 1.1e-17 64.0 0.1 1.6e-17 63.5 0.1 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EER26417.1 - 1.9e-09 37.6 0.0 2e-08 34.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EER26417.1 - 1.1e-06 28.0 0.1 3.5e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EER26417.1 - 2e-05 24.1 0.1 0.00061 19.2 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EER26417.1 - 0.0074 15.7 0.2 0.022 14.1 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER26417.1 - 0.01 15.5 0.1 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain MipZ PF09140.6 EER26417.1 - 0.012 14.6 0.1 0.039 13.0 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ IstB_IS21 PF01695.12 EER26417.1 - 0.025 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 EER26417.1 - 0.026 13.7 0.0 0.074 12.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein YhjQ PF06564.7 EER26417.1 - 0.027 13.8 0.0 0.063 12.6 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein NB-ARC PF00931.17 EER26417.1 - 0.053 12.3 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain A1_Propeptide PF07966.7 EER26417.1 - 0.53 10.1 0.1 0.53 10.1 0.1 2.3 3 0 0 3 3 2 0 A1 Propeptide eIF3_N PF09440.5 EER26419.1 - 1.2e-51 174.3 1.9 1.2e-51 174.3 1.4 1.8 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EER26419.1 - 1.4e-14 54.2 0.0 9e-14 51.6 0.0 2.4 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EER26419.1 - 0.0046 16.7 0.1 0.021 14.6 0.0 2.1 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 Img2 PF05046.9 EER26420.1 - 7e-27 93.4 0.0 1.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.16 EER26421.1 - 8e-18 64.0 0.0 1.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.24 EER26422.1 - 1.8e-45 154.3 0.1 6.6e-45 152.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EER26422.1 - 3.6e-09 36.4 0.5 1.2e-08 34.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EER26422.1 - 4.2e-08 33.3 0.0 9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EER26422.1 - 4.5e-07 30.0 0.0 1.5e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EER26422.1 - 8.1e-07 29.2 0.6 0.001 19.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EER26422.1 - 2.7e-06 26.5 0.0 5.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EER26422.1 - 6.5e-05 22.8 0.0 0.00058 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER26422.1 - 0.00013 22.7 0.0 0.0019 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EER26422.1 - 0.00035 19.7 0.0 0.00081 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EER26422.1 - 0.00042 20.2 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EER26422.1 - 0.00049 19.7 0.3 0.056 13.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Zeta_toxin PF06414.7 EER26422.1 - 0.0012 17.9 0.1 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EER26422.1 - 0.0013 18.4 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EER26422.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EER26422.1 - 0.0026 16.5 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 EER26422.1 - 0.0031 17.2 0.0 0.0093 15.6 0.0 1.8 2 0 0 2 2 1 1 NTPase AAA_3 PF07726.6 EER26422.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EER26422.1 - 0.0046 16.5 0.0 0.039 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 EER26422.1 - 0.0046 16.5 0.3 0.016 14.8 0.0 2.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EER26422.1 - 0.0052 16.6 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EER26422.1 - 0.0067 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 EER26422.1 - 0.0068 15.9 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EER26422.1 - 0.0086 15.5 0.4 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein Arch_ATPase PF01637.13 EER26422.1 - 0.0097 15.6 1.0 0.06 13.0 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase AAA_23 PF13476.1 EER26422.1 - 0.013 15.8 0.6 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EER26422.1 - 0.014 15.0 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EER26422.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 EER26422.1 - 0.024 14.0 3.3 0.078 12.3 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 EER26422.1 - 0.025 14.9 0.0 0.096 12.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain KaiC PF06745.8 EER26422.1 - 0.028 13.5 0.8 0.46 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 EER26422.1 - 0.047 13.1 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EER26422.1 - 0.064 13.2 0.1 0.31 11.0 0.0 2.3 2 1 0 2 2 1 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 EER26422.1 - 0.1 10.8 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.17 EER26422.1 - 0.11 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EER26422.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Asp PF00026.18 EER26423.1 - 2.9e-106 355.3 0.0 3.6e-106 355.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EER26423.1 - 4.9e-11 42.8 0.0 1.3e-10 41.4 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EER26423.1 - 2.4e-06 27.9 0.0 0.023 15.1 0.0 3.3 2 2 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EER26423.1 - 0.0002 20.9 0.0 0.0015 18.0 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EER26423.1 - 0.13 12.1 0.0 6.5 6.6 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease KaiA PF07688.7 EER26423.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 KaiA domain NIF PF03031.13 EER26424.1 - 5e-27 94.5 0.0 9.8e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EER26424.1 - 2.3e-11 43.3 0.1 4.6e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EER26424.1 - 3e-08 33.7 0.0 7.4e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl_2 PF13533.1 EER26424.1 - 0.00067 19.2 0.0 1.4 8.6 0.0 2.9 2 0 0 2 2 2 2 Biotin-lipoyl like MARVEL PF01284.18 EER26425.1 - 0.0016 18.2 18.8 0.0039 17.0 13.0 1.7 1 1 0 1 1 1 1 Membrane-associating domain Peptidase_S68 PF10461.4 EER26425.1 - 0.15 11.8 0.5 0.38 10.4 0.4 1.7 1 0 0 1 1 1 0 Peptidase S68 Arginase PF00491.16 EER26426.1 - 5e-73 245.7 0.6 5.8e-73 245.5 0.4 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.10 EER26427.1 - 6.1e-80 268.1 0.0 8.2e-80 267.7 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EER26427.1 - 9.2e-22 77.3 0.0 1.6e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 GatB domain NfeD PF01957.13 EER26428.1 - 4.3 7.4 4.8 6.2 6.9 3.3 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding Bromodomain PF00439.20 EER26429.1 - 0.08 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Bromodomain ECH PF00378.15 EER26431.1 - 5e-50 169.9 0.1 6.2e-50 169.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pox_P21 PF05313.7 EER26431.1 - 0.047 12.9 0.0 0.07 12.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus P21 membrane protein DUF676 PF05057.9 EER26432.1 - 0.00025 20.3 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EER26432.1 - 0.00059 19.4 0.0 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EER26432.1 - 0.0011 18.8 0.1 0.0037 17.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EER26432.1 - 0.0023 18.0 0.0 0.009 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER26432.1 - 0.0092 15.9 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Mst1_SARAH PF11629.3 EER26432.1 - 0.52 10.1 3.7 16 5.3 0.1 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF883 PF05957.8 EER26433.1 - 0.041 14.2 5.2 0.041 14.2 3.6 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Ycf1 PF05758.7 EER26433.1 - 0.22 9.1 1.1 0.25 9.0 0.7 1.0 1 0 0 1 1 1 0 Ycf1 YtxH PF12732.2 EER26433.1 - 0.36 11.2 8.7 3.2 8.1 0.5 2.1 1 1 1 2 2 2 0 YtxH-like protein ISG65-75 PF11727.3 EER26433.1 - 0.77 8.7 7.4 0.96 8.4 5.2 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Neuromodulin_N PF10580.4 EER26433.1 - 6.8 6.4 6.9 13 5.5 0.1 2.3 2 0 0 2 2 2 0 Gap junction protein N-terminal region FHA PF00498.21 EER26434.1 - 1.9e-12 47.1 0.0 3.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain DnaJ PF00226.26 EER26435.1 - 1.7e-08 34.0 0.3 3.5e-08 33.0 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.8 EER26436.1 - 1.7e-38 132.3 0.0 2.3e-37 128.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER26436.1 - 0.0016 18.1 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EER26436.1 - 0.0054 15.4 0.0 0.014 14.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) HMG_box PF00505.14 EER26440.1 - 2.3e-25 88.6 1.2 2.3e-25 88.6 0.9 1.5 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EER26440.1 - 7e-21 74.3 1.6 1.2e-20 73.5 1.1 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EER26440.1 - 0.0013 18.5 0.8 0.0013 18.5 0.6 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EER26440.1 - 0.039 14.1 3.0 0.049 13.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) DEADboxA PF12343.3 EER26440.1 - 0.048 13.9 2.7 0.26 11.5 1.9 2.0 1 1 0 1 1 1 0 Cold shock protein DEAD box A Prp31_C PF09785.4 EER26440.1 - 0.18 12.2 5.4 0.21 12.0 3.7 1.1 1 0 0 1 1 1 0 Prp31 C terminal domain APH PF01636.18 EER26442.1 - 7.1e-11 42.2 0.9 3.7e-10 39.9 0.2 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER26442.1 - 0.0047 16.5 0.0 0.0073 15.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EER26442.1 - 0.093 12.0 0.0 0.2 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family CENP-H PF05837.7 EER26443.1 - 1.4e-19 70.2 5.0 1.4e-19 70.2 3.5 1.6 2 0 0 2 2 2 1 Centromere protein H (CENP-H) ATG11 PF10377.4 EER26444.1 - 9.1e-41 138.7 0.2 9.1e-41 138.7 0.1 3.7 3 1 1 4 4 4 1 Autophagy-related protein 11 APG17 PF04108.7 EER26444.1 - 5.7e-05 22.0 0.1 5.7e-05 22.0 0.1 4.6 2 2 0 3 3 3 1 Autophagy protein Apg17 Shugoshin_N PF07558.6 EER26444.1 - 0.6 9.8 8.9 1.6 8.5 0.3 3.9 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF4078 PF13300.1 EER26445.1 - 1.5e-31 108.3 9.3 1.5e-31 108.3 6.5 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4078) Homoserine_dh PF00742.14 EER26446.1 - 1.7e-51 174.3 0.0 2.4e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EER26446.1 - 1.9e-12 47.5 0.0 6.4e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF3445 PF11927.3 EER26447.1 - 2.6e-83 279.2 0.0 3.2e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) HAD_2 PF13419.1 EER26448.1 - 0.0054 16.9 0.0 0.056 13.6 0.0 2.0 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Phage_head_chap PF11113.3 EER26448.1 - 0.015 15.1 0.0 0.091 12.6 0.0 2.2 3 0 0 3 3 3 0 Head assembly gene product DUF3294 PF07957.6 EER26448.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DUF221 PF02714.10 EER26450.1 - 4.3e-92 308.4 19.1 6.6e-92 307.8 13.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EER26450.1 - 1.3e-42 145.0 0.1 1.3e-42 145.0 0.1 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EER26450.1 - 6.5e-18 65.0 0.1 1.5e-17 63.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DHO_dh PF01180.16 EER26450.1 - 0.28 10.0 0.0 0.5 9.2 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase HNH_2 PF13391.1 EER26451.1 - 1.9e-14 53.1 0.0 3.3e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease F_bP_aldolase PF01116.15 EER26452.1 - 2.5e-97 325.4 0.0 2.8e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.24 EER26453.1 - 2.3e-41 141.6 0.0 2.6e-34 118.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER26453.1 - 2.7e-12 46.7 0.0 2.2e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Kinesin-relat_1 PF12711.2 EER26453.1 - 0.15 12.5 0.3 0.54 10.6 0.1 2.0 2 0 0 2 2 2 0 Kinesin motor Rubredoxin PF00301.15 EER26453.1 - 0.19 11.5 1.1 1.9 8.3 0.1 2.5 2 0 0 2 2 2 0 Rubredoxin GPCR_chapero_1 PF11904.3 EER26454.1 - 8 5.4 9.8 9.8 5.2 6.8 1.1 1 0 0 1 1 1 0 GPCR-chaperone PPP4R2 PF09184.6 EER26454.1 - 9.6 5.6 11.8 12 5.3 8.2 1.2 1 0 0 1 1 1 0 PPP4R2 CUE PF02845.11 EER26456.1 - 1.1e-11 44.0 0.0 1.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain RTA1 PF04479.8 EER26457.1 - 9.4e-34 116.8 3.0 1.2e-33 116.5 2.1 1.1 1 0 0 1 1 1 1 RTA1 like protein Oxysterol_BP PF01237.13 EER26458.1 - 5.5e-89 298.1 0.0 6.5e-89 297.8 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Kinesin-relat_1 PF12711.2 EER26458.1 - 0.00014 22.2 0.1 0.033 14.5 0.0 2.6 2 1 0 2 2 2 2 Kinesin motor Sugar_tr PF00083.19 EER26459.1 - 1.7e-77 260.9 13.3 2.2e-77 260.5 9.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER26459.1 - 9e-15 54.2 22.6 1.7e-14 53.3 15.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PUD PF03714.9 EER26461.1 - 0.33 11.1 3.8 7.3 6.7 0.1 2.3 2 0 0 2 2 2 0 Bacterial pullanase-associated domain RNase_T PF00929.19 EER26462.1 - 4e-24 85.7 0.0 4.6e-24 85.5 0.0 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.11 EER26463.1 - 3.6e-34 117.1 0.2 5.5e-34 116.6 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EER26463.1 - 1.1e-26 93.0 0.0 2.1e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EER26463.1 - 9.3e-17 61.2 0.0 3.1e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EER26463.1 - 1.1e-10 41.3 0.0 2.5e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.17 EER26464.1 - 1.5e-12 48.0 0.0 4.4e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EER26464.1 - 0.00028 20.6 0.0 0.00067 19.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Acetyltransf_7 PF13508.1 EER26466.1 - 3.6e-10 39.8 0.0 7.2e-10 38.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER26466.1 - 2.8e-09 36.8 0.1 4.6e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EER26466.1 - 2.4e-08 34.1 0.0 5e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER26466.1 - 5.3e-07 29.5 0.0 1.1e-06 28.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER26466.1 - 0.00094 19.0 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EER26466.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.6 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 EER26466.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HMG_CoA_synt_C PF08540.5 EER26467.1 - 2.4e-103 345.4 0.1 3e-103 345.1 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EER26467.1 - 3.3e-95 316.5 0.1 5.5e-95 315.8 0.1 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Pkinase PF00069.20 EER26468.1 - 7.4e-26 90.8 0.0 3.9e-21 75.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER26468.1 - 4.3e-07 29.2 0.0 0.00046 19.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Nnf1 PF03980.9 EER26469.1 - 2.1e-29 101.7 0.1 3.9e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Nnf1 CR6_interact PF10147.4 EER26469.1 - 0.01 15.1 0.7 0.21 10.8 0.1 2.1 2 0 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DMPK_coil PF08826.5 EER26469.1 - 0.018 14.8 0.3 0.018 14.8 0.2 1.9 2 0 0 2 2 2 0 DMPK coiled coil domain like APH PF01636.18 EER26471.1 - 6.7e-13 48.9 0.3 1.2e-12 48.1 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EER26471.1 - 0.051 12.9 0.0 9.5 5.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 EER26472.1 - 1e-18 67.9 0.0 1.6e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EER26472.1 - 1.9e-05 23.8 0.0 0.07 12.1 0.0 2.6 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EER26472.1 - 0.00063 19.3 0.0 0.00099 18.7 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EER26472.1 - 0.017 14.4 0.1 1.3 8.3 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 EER26472.1 - 0.063 12.4 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain TFR_dimer PF04253.10 EER26473.1 - 8.6e-29 99.6 0.1 1.4e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EER26473.1 - 1.5e-17 63.9 0.0 5.2e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EER26473.1 - 6.6e-08 32.1 0.1 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 PA domain TFIIB PF00382.14 EER26474.1 - 5.2e-38 128.6 0.1 1.7e-19 69.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EER26474.1 - 2.6e-11 42.6 0.6 2.6e-11 42.6 0.4 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding HTH_23 PF13384.1 EER26474.1 - 0.049 13.2 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain DZR PF12773.2 EER26474.1 - 0.092 12.5 1.2 0.41 10.4 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon ATP_sub_h PF10775.4 EER26475.1 - 9.9e-27 92.4 2.8 1.6e-26 91.7 2.0 1.4 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EER26475.1 - 0.0002 21.2 0.2 0.00033 20.5 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial ATP synthase coupling factor 6 DUF1765 PF08578.5 EER26476.1 - 1.6e-44 151.0 0.5 3.2e-44 150.0 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) Serglycin PF04360.7 EER26476.1 - 0.023 14.4 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Serglycin DUF3210 PF11489.3 EER26477.1 - 2.9e-188 627.8 81.4 2.9e-188 627.8 56.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 EER26478.1 - 1e-34 118.9 10.5 1.2e-34 118.6 7.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Imm10 PF15562.1 EER26478.1 - 0.17 11.6 5.9 0.29 10.9 0.0 3.4 4 0 0 4 4 4 0 Immunity protein 10 zf-DHHC PF01529.15 EER26478.1 - 0.17 11.2 3.5 0.22 10.8 2.4 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase PRA1 PF03208.14 EER26478.1 - 0.43 9.9 9.6 1 8.6 6.7 1.6 1 1 0 1 1 1 0 PRA1 family protein DUF624 PF04854.9 EER26478.1 - 0.66 9.8 5.7 1.9 8.4 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function, DUF624 DUF3040 PF11239.3 EER26478.1 - 2.3 8.3 6.3 14 5.8 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) PfkB PF00294.19 EER26479.1 - 9.6e-22 77.4 0.0 9e-15 54.5 0.0 2.0 2 0 0 2 2 2 2 pfkB family carbohydrate kinase NTF2 PF02136.15 EER26480.1 - 2.5e-33 114.9 0.0 2.8e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Surp PF01805.15 EER26481.1 - 1.1e-15 56.9 0.0 2.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Surp module Rick_17kDa_Anti PF05433.10 EER26483.1 - 0.003 17.1 0.3 0.005 16.4 0.2 1.3 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EER26483.1 - 0.034 13.7 1.1 0.057 13.0 0.7 1.3 1 0 0 1 1 1 0 Glycine zipper DUF3169 PF11368.3 EER26483.1 - 0.35 10.0 0.1 0.49 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Ish1 PF10281.4 EER26484.1 - 8.8e-67 220.7 25.6 3.8e-13 49.2 0.0 8.5 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EER26484.1 - 1.9e-07 30.4 0.0 0.14 11.7 0.0 5.4 6 0 0 6 6 6 1 SAP domain HeH PF12949.2 EER26484.1 - 5.1e-07 29.1 0.3 5.4 6.6 0.0 5.4 5 0 0 5 5 5 3 HeH/LEM domain Slx4 PF09494.5 EER26484.1 - 2.4e-05 23.9 0.2 9.5 6.0 0.0 5.0 4 0 0 4 4 4 1 Slx4 endonuclease APC2 PF08672.6 EER26484.1 - 0.0014 18.8 1.6 57 4.0 0.0 5.7 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 Tir_receptor_M PF03549.9 EER26484.1 - 0.0021 18.1 0.0 9.3 6.4 0.0 3.7 2 1 1 3 3 3 1 Translocated intimin receptor (Tir) intimin-binding domain PQ-loop PF04193.9 EER26485.1 - 5.8e-19 67.3 20.7 4.4e-11 42.1 2.2 3.5 3 1 1 4 4 4 2 PQ loop repeat DUF1345 PF07077.6 EER26485.1 - 0.06 12.8 3.8 0.079 12.4 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF1634 PF07843.6 EER26485.1 - 0.062 12.9 4.3 0.086 12.4 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) DUF3796 PF12676.2 EER26485.1 - 0.15 12.2 6.0 0.038 14.2 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) DUF1143 PF06608.6 EER26486.1 - 0.091 12.7 0.7 0.12 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1143) Umbravirus_LDM PF04817.7 EER26486.1 - 0.15 11.2 2.8 0.21 10.6 1.9 1.5 1 1 0 1 1 1 0 Umbravirus long distance movement (LDM) family Glyco_transf_90 PF05686.7 EER26487.1 - 3.2e-14 52.4 1.1 8.8e-12 44.3 0.5 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Cyt-b5 PF00173.23 EER26488.1 - 2e-15 56.3 0.0 2.8e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF3610 PF12272.3 EER26488.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3610) DUF908 PF06012.7 EER26489.1 - 0.095 11.9 0.3 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TMA7 PF09072.5 EER26490.1 - 2.9e-25 88.5 17.4 3.4e-25 88.2 12.1 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.20 EER26491.1 - 3.3e-53 180.4 0.0 5e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26491.1 - 7.1e-24 84.2 0.0 2.9e-23 82.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EER26491.1 - 0.0007 19.4 0.1 1.2 8.8 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EER26491.1 - 0.027 13.2 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EER26492.1 - 8.6e-60 202.0 0.0 1.2e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26492.1 - 1.6e-33 115.9 0.0 2e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26492.1 - 0.017 14.1 0.0 0.028 13.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 EER26492.1 - 0.021 14.5 0.0 0.061 13.0 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EER26492.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 EER26493.1 - 8.9e-35 120.0 2.2 8.9e-35 120.0 1.5 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER26493.1 - 8.5e-27 94.4 0.4 2.8e-26 92.7 0.3 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER26493.1 - 2.1e-16 60.1 0.7 2.9e-16 59.6 0.5 1.2 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 EER26493.1 - 0.0031 17.4 0.2 0.0063 16.5 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain 3HCDH_N PF02737.13 EER26493.1 - 0.0032 17.1 0.9 0.006 16.2 0.6 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EER26493.1 - 0.0035 16.3 0.2 0.0051 15.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Methyltransf_25 PF13649.1 EER26493.1 - 0.0046 17.2 0.0 0.0085 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER26493.1 - 0.0092 16.0 0.1 0.021 14.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 EER26493.1 - 0.044 12.6 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.9 EER26493.1 - 0.061 12.6 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4410 PF14366.1 EER26493.1 - 0.066 12.9 0.2 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) 2-Hacid_dh_C PF02826.14 EER26493.1 - 0.072 12.2 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HlyIII PF03006.15 EER26494.1 - 7.5e-63 211.9 21.0 8.8e-63 211.6 14.6 1.0 1 0 0 1 1 1 1 Haemolysin-III related 60KD_IMP PF02096.15 EER26494.1 - 0.037 13.7 1.3 0.063 12.9 0.9 1.5 1 1 0 1 1 1 0 60Kd inner membrane protein SAC3_GANP PF03399.11 EER26495.1 - 6e-05 22.6 0.0 8.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_19 PF14559.1 EER26496.1 - 4.6e-06 26.8 0.0 0.25 11.6 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EER26496.1 - 0.097 12.3 0.2 0.74 9.5 0.0 2.4 3 0 0 3 3 3 0 TPR repeat TPR_4 PF07721.9 EER26496.1 - 0.12 12.9 0.7 58 4.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.21 EER26497.1 - 4.2e-31 107.8 0.0 5.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EER26497.1 - 8.4e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EER26497.1 - 3.4e-07 29.6 0.0 7e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EER26497.1 - 0.00091 18.5 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EER26497.1 - 0.038 13.7 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 EER26497.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF1749 PF08538.5 EER26498.1 - 2.3e-98 328.8 0.0 2.5e-98 328.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 EER26498.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3992 PF13157.1 EER26500.1 - 0.75 10.0 6.0 1.3 9.2 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) Phosphoprotein PF00922.12 EER26500.1 - 4.6 6.3 11.0 7.2 5.7 7.6 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Vps35 PF03635.12 EER26501.1 - 0 1023.0 3.3 0 1022.8 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RIH_assoc PF08454.6 EER26501.1 - 0.23 11.1 4.3 2.1 8.0 0.1 3.5 3 0 0 3 3 3 0 RyR and IP3R Homology associated Xpo1 PF08389.7 EER26501.1 - 0.24 11.2 5.1 3.7 7.4 0.0 4.0 6 0 0 6 6 6 0 Exportin 1-like protein NST1 PF13945.1 EER26502.1 - 2.6e-82 275.5 8.2 2.6e-82 275.5 5.7 5.9 4 1 2 6 6 6 1 Salt tolerance down-regulator Ras PF00071.17 EER26503.1 - 7.3e-50 168.5 0.0 8.5e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER26503.1 - 2.7e-17 63.3 0.0 6e-17 62.2 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EER26503.1 - 1e-06 28.1 0.0 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER26503.1 - 0.0021 17.2 0.0 0.0023 17.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EER26503.1 - 0.011 14.9 0.0 0.015 14.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EER26503.1 - 0.015 14.8 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EER26503.1 - 0.038 13.9 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EER26503.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 EER26504.1 - 3.9e-08 33.2 0.0 5.7e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RINGv PF12906.2 EER26505.1 - 1.7e-06 27.9 5.8 3.4e-06 26.9 4.0 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EER26505.1 - 4.7e-05 23.2 3.0 9e-05 22.3 2.1 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EER26505.1 - 0.0011 18.7 4.6 0.0021 17.8 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain TPP_enzyme_N PF02776.13 EER26506.1 - 1.2e-56 190.9 0.1 5.3e-56 188.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EER26506.1 - 1.6e-50 170.6 0.5 7.4e-48 162.0 0.0 3.3 3 1 0 3 3 3 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EER26506.1 - 7.6e-37 126.1 0.4 2.8e-36 124.3 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EER26506.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg GalKase_gal_bdg PF10509.4 EER26507.1 - 2e-18 65.3 0.0 3.9e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EER26507.1 - 1.2e-14 54.1 2.4 2e-14 53.4 0.7 2.2 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EER26507.1 - 2.2e-13 50.2 0.0 4.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r4_2 PF08281.7 EER26507.1 - 0.05 13.0 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 DED PF01335.16 EER26507.1 - 0.07 13.2 0.2 0.23 11.6 0.1 1.8 1 0 0 1 1 1 0 Death effector domain RNase_H2-Ydr279 PF09468.5 EER26508.1 - 2.2e-79 266.8 1.4 2.9e-79 266.4 1.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) zf-primase PF09329.6 EER26509.1 - 1.8e-18 65.8 0.7 3e-18 65.1 0.5 1.4 1 0 0 1 1 1 1 Primase zinc finger DASH_Duo1 PF08651.5 EER26511.1 - 2.1e-30 104.1 0.8 3.7e-30 103.3 0.5 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 Macoilin PF09726.4 EER26511.1 - 0.0022 16.3 6.0 0.0025 16.1 4.2 1.2 1 0 0 1 1 1 1 Transmembrane protein DUF2514 PF10721.4 EER26511.1 - 0.098 12.3 15.6 0.16 11.6 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF1822 PF08852.6 EER26511.1 - 0.15 10.8 4.7 0.2 10.4 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Tic20 PF09685.5 EER26512.1 - 1.8e-07 31.0 3.0 2.5e-07 30.6 2.1 1.2 1 0 0 1 1 1 1 Tic20-like protein Reticulon PF02453.12 EER26512.1 - 0.043 13.4 0.6 0.063 12.8 0.4 1.2 1 0 0 1 1 1 0 Reticulon FCH PF00611.18 EER26513.1 - 1e-20 73.6 0.0 5e-20 71.4 0.0 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EER26513.1 - 1.3e-12 46.8 0.0 2.6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EER26513.1 - 3.3e-10 39.2 0.0 1.8e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EER26513.1 - 4.1e-09 35.8 0.0 7.7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Paramyxo_NS_C PF02725.9 EER26513.1 - 5.2 6.6 0.0 5.2 6.6 0.0 3.0 2 0 0 2 2 2 0 Non-structural protein C Not1 PF04054.10 EER26514.1 - 1.3e-137 458.7 0.0 7.4e-137 456.2 0.0 2.3 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EER26514.1 - 2.2e-50 170.1 3.6 3.5e-50 169.5 1.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3819) Peptidase_M17_N PF02789.12 EER26514.1 - 0.18 11.5 0.5 14 5.4 0.0 2.7 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Seipin PF06775.9 EER26515.1 - 4.1e-62 209.2 1.0 5.3e-62 208.8 0.7 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) TTL PF03133.10 EER26516.1 - 1.1e-56 191.9 0.0 1.5e-56 191.4 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EER26516.1 - 1.9e-40 138.2 0.0 2.9e-40 137.7 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EER26516.1 - 0.00045 19.1 0.0 0.0049 15.7 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EER26516.1 - 0.0017 18.1 0.2 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Glyco_transf_4 PF13439.1 EER26516.1 - 0.042 13.5 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Dala_Dala_lig_C PF07478.8 EER26516.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus DUF2457 PF10446.4 EER26516.1 - 2.7 6.6 8.3 4.2 5.9 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ADH_N PF08240.7 EER26517.1 - 2.4e-25 88.4 2.8 4.6e-25 87.5 2.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER26517.1 - 2e-16 59.6 0.0 3.1e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EER26517.1 - 0.00014 21.0 0.0 0.00021 20.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EER26517.1 - 0.003 17.1 0.0 0.01 15.4 0.0 1.7 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_2 PF03446.10 EER26517.1 - 0.041 13.7 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 EER26517.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EER26517.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ABC_tran PF00005.22 EER26518.1 - 9.5e-33 113.4 0.0 3.8e-32 111.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EER26518.1 - 2.3e-19 69.9 3.7 3.1e-19 69.4 2.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EER26518.1 - 1.6e-05 24.2 0.2 0.0048 16.1 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER26518.1 - 0.00054 20.0 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EER26518.1 - 0.0011 19.2 0.1 0.0028 17.9 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EER26518.1 - 0.0042 16.5 0.2 0.013 14.9 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EER26518.1 - 0.0065 17.2 0.1 0.044 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EER26518.1 - 0.03 14.1 0.2 0.055 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 SbcCD_C PF13558.1 EER26518.1 - 0.055 13.3 0.0 0.33 10.8 0.0 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EER26518.1 - 0.058 13.5 0.1 0.15 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EER26518.1 - 0.063 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pex14_N PF04695.8 EER26520.1 - 1.4e-41 141.6 0.0 1.4e-41 141.6 0.0 3.3 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.3 EER26520.1 - 0.00077 16.9 2.3 0.00098 16.6 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) IncA PF04156.9 EER26520.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 IncA protein zf-C4H2 PF10146.4 EER26520.1 - 0.023 14.7 2.3 0.055 13.4 1.6 1.6 1 1 0 1 1 1 0 Zinc finger-containing protein Baculo_PEP_C PF04513.7 EER26520.1 - 0.089 12.6 0.6 2.5 7.9 0.2 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lebercilin PF15619.1 EER26520.1 - 0.17 11.2 4.3 0.27 10.6 3.0 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease ERM PF00769.14 EER26520.1 - 0.51 9.8 6.7 0.96 8.9 4.6 1.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF3275 PF11679.3 EER26520.1 - 3 7.4 13.2 0.27 10.8 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Ndc80_HEC PF03801.8 EER26521.1 - 1.9e-62 209.4 1.0 4e-62 208.3 0.2 2.0 2 0 0 2 2 2 1 HEC/Ndc80p family Pkinase PF00069.20 EER26523.1 - 3.4e-62 209.9 0.0 4.3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26523.1 - 9.6e-28 96.9 0.0 1.5e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER26523.1 - 0.095 11.6 0.0 0.18 10.7 0.0 1.5 1 1 0 1 1 1 0 Kinase-like FolB PF02152.13 EER26524.1 - 3.1e-23 82.0 0.0 6.2e-20 71.4 0.1 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase RRM_1 PF00076.17 EER26525.1 - 4.8e-22 77.3 0.0 2.9e-11 42.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER26525.1 - 2.7e-16 59.3 0.0 3.8e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER26525.1 - 2e-13 49.9 0.0 1.7e-05 24.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EER26525.1 - 0.12 12.2 0.0 8.3 6.3 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif ETF_QO PF05187.8 EER26526.1 - 7.2e-46 154.7 0.0 1.2e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EER26526.1 - 1.1e-09 37.6 0.0 0.00025 20.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EER26526.1 - 1.6e-06 27.2 0.1 0.0023 16.8 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EER26526.1 - 1.8e-06 27.8 0.0 4.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EER26526.1 - 9.7e-05 21.5 0.0 0.0027 16.8 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EER26526.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER26526.1 - 0.00018 21.6 0.0 0.0003 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EER26526.1 - 0.00022 20.4 0.0 0.00038 19.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EER26526.1 - 0.00022 19.8 0.5 0.00037 19.1 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EER26526.1 - 0.0026 18.1 0.0 2.8 8.4 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EER26526.1 - 0.0028 16.3 0.0 0.084 11.4 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_3 PF01494.14 EER26526.1 - 0.0039 16.2 1.1 0.0044 16.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EER26526.1 - 0.0055 16.4 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.2 EER26526.1 - 0.0087 16.4 0.8 0.03 14.7 0.5 1.9 1 0 0 1 1 1 1 4Fe-4S dicluster domain Amino_oxidase PF01593.19 EER26526.1 - 0.024 13.7 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EER26526.1 - 0.071 12.0 0.3 0.1 11.4 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EER26526.1 - 0.1 11.4 0.5 0.16 10.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.16 EER26527.1 - 3.6e-70 231.3 0.1 3.6e-35 119.1 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EER26527.1 - 9.6e-05 22.3 0.0 0.4 10.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DAO PF01266.19 EER26528.1 - 2.3e-54 184.6 0.2 2.8e-54 184.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EER26528.1 - 3.1e-06 27.2 0.1 0.0014 18.5 0.0 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER26528.1 - 5.3e-05 23.1 0.0 0.00067 19.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EER26528.1 - 8.5e-05 22.3 0.8 0.08 12.7 0.1 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EER26528.1 - 0.00039 20.7 0.0 0.0014 19.0 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EER26528.1 - 0.00059 18.8 0.0 0.013 14.3 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EER26528.1 - 0.00085 18.0 0.1 0.0082 14.8 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EER26528.1 - 0.0019 17.1 0.0 0.3 9.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EER26528.1 - 0.0067 15.3 0.1 0.02 13.8 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EER26528.1 - 0.011 14.8 0.0 0.17 10.8 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain GMC_oxred_N PF00732.14 EER26528.1 - 0.052 12.6 0.0 0.47 9.5 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase TrkA_N PF02254.13 EER26528.1 - 0.099 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_23 PF13489.1 EER26529.1 - 1.3e-20 73.7 0.0 1.8e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER26529.1 - 8e-06 26.1 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER26529.1 - 1.2e-05 25.7 0.0 2.2e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER26529.1 - 9.1e-05 22.0 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER26529.1 - 0.00084 19.8 0.0 0.0024 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER26529.1 - 0.00089 19.7 0.0 0.0072 16.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Cyclin_N PF00134.18 EER26531.1 - 9.5e-16 57.5 0.1 3.4e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EER26531.1 - 1.2e-08 34.8 0.1 6.7e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Cyclin, C-terminal domain TFIIB PF00382.14 EER26531.1 - 0.0028 17.4 1.9 0.64 9.8 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat EAF PF09816.4 EER26532.1 - 7.6e-21 74.1 0.0 1.3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor NPFF PF15085.1 EER26532.1 - 2.1 8.6 7.0 4.3 7.6 4.8 1.6 1 0 0 1 1 1 0 Neuropeptide FF Dor1 PF04124.7 EER26533.1 - 2.7e-52 177.3 8.2 2.6e-46 157.6 3.9 2.9 1 1 1 2 2 2 2 Dor1-like family Vps51 PF08700.6 EER26533.1 - 7.5e-05 22.5 1.5 7.5e-05 22.5 1.0 2.1 2 0 0 2 2 2 1 Vps51/Vps67 SLX9 PF15341.1 EER26533.1 - 0.033 14.6 3.3 4.9 7.6 0.0 3.4 2 1 1 3 3 3 0 Ribosome biogenesis protein SLX9 IncA PF04156.9 EER26533.1 - 2.5 7.6 9.3 0.13 11.8 1.5 2.1 2 0 0 2 2 2 0 IncA protein His_Phos_1 PF00300.17 EER26534.1 - 1e-19 71.1 0.0 2.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PAXIP1_C PF15364.1 EER26534.1 - 0.046 13.6 1.9 0.14 12.0 1.3 1.8 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein Cyclin PF08613.6 EER26535.1 - 2.4e-13 50.7 0.0 3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin CRC_subunit PF08624.5 EER26536.1 - 3.8e-57 192.0 0.1 6e-57 191.4 0.1 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit SCIMP PF15050.1 EER26536.1 - 3.1 7.7 5.9 1.4 8.8 2.2 1.9 1 1 0 1 1 1 0 SCIMP protein DUF4246 PF14033.1 EER26537.1 - 4.2e-191 635.9 0.2 5.2e-191 635.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EER26537.1 - 0.00028 21.1 0.0 0.00086 19.5 0.0 1.8 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Acyltransferase PF01553.16 EER26538.1 - 1.3e-08 34.3 0.0 2.7e-07 30.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 EER26539.1 - 2.2e-71 240.0 0.0 3.2e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26539.1 - 3.6e-31 108.1 0.0 5.1e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EER26539.1 - 8.3e-12 45.4 0.3 4.9e-11 42.9 0.2 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EER26539.1 - 3.7e-09 35.9 0.1 7.3e-09 34.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 EER26539.1 - 0.00094 18.9 0.0 0.0045 16.7 0.0 2.2 1 1 0 1 1 1 1 C2 domain APH PF01636.18 EER26539.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EER26539.1 - 0.056 12.7 0.1 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RCR PF12273.3 EER26539.1 - 0.2 12.2 3.1 0.28 11.7 0.1 2.4 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red F-box-like PF12937.2 EER26540.1 - 0.0021 17.7 0.4 0.0064 16.1 0.3 1.9 1 0 0 1 1 1 1 F-box-like AAA PF00004.24 EER26541.1 - 8.1e-40 136.0 0.0 1.8e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EER26541.1 - 0.00017 21.3 1.4 0.00078 19.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EER26541.1 - 0.00024 21.1 0.1 0.017 15.0 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EER26541.1 - 0.00025 20.1 0.0 0.00066 18.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EER26541.1 - 0.00039 20.5 0.1 0.019 15.1 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EER26541.1 - 0.00073 19.4 0.0 0.0089 15.9 0.0 2.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EER26541.1 - 0.00074 18.5 1.5 0.03 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) PhoH PF02562.11 EER26541.1 - 0.0043 16.2 0.3 0.048 12.8 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EER26541.1 - 0.0067 15.6 0.1 0.02 14.0 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EER26541.1 - 0.0078 16.0 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER26541.1 - 0.017 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EER26541.1 - 0.022 14.1 0.1 0.047 13.0 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EER26541.1 - 0.039 13.3 1.6 0.36 10.2 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EER26541.1 - 0.087 13.6 0.1 0.087 13.6 0.1 3.2 2 2 0 2 2 1 0 AAA domain AAA_11 PF13086.1 EER26541.1 - 0.81 9.2 0.0 0.81 9.2 0.0 2.7 2 1 0 2 2 1 0 AAA domain TauD PF02668.11 EER26542.1 - 3.5e-45 154.6 0.1 4.9e-45 154.2 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EER26542.1 - 2.5e-07 31.0 0.0 6.7e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 EER26542.1 - 0.075 13.5 0.1 5 7.6 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily MaoC_dehydratas PF01575.14 EER26543.1 - 1.6e-25 88.8 0.0 2.9e-25 88.0 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EER26543.1 - 1.4e-11 44.2 0.0 8.5e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase SIC PF03482.8 EER26543.1 - 0.043 13.4 1.2 0.063 12.8 0.8 1.2 1 0 0 1 1 1 0 sic protein Methyltransf_31 PF13847.1 EER26544.1 - 6.1e-12 45.3 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EER26544.1 - 5.7e-11 42.0 0.0 8.8e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EER26544.1 - 7.7e-10 38.8 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER26544.1 - 2.9e-09 37.5 0.0 9.3e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 EER26544.1 - 3.2e-08 32.9 0.0 4.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EER26544.1 - 1.5e-07 31.8 0.0 4.9e-07 30.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EER26544.1 - 6.5e-07 28.3 0.1 1e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 EER26544.1 - 5.6e-06 26.1 0.0 2e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EER26544.1 - 1.7e-05 24.2 0.0 2.8e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EER26544.1 - 2.2e-05 24.7 0.1 0.0001 22.6 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain CMAS PF02353.15 EER26544.1 - 0.00014 21.0 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EER26544.1 - 0.00021 21.3 0.0 0.00075 19.5 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EER26544.1 - 0.00032 21.1 0.0 0.00069 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EER26544.1 - 0.0025 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.14 EER26544.1 - 0.0094 15.5 0.2 0.017 14.6 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EER26544.1 - 0.014 14.5 0.1 0.03 13.4 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EER26544.1 - 0.025 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EER26544.1 - 0.078 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 EER26544.1 - 0.086 11.9 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 EER26544.1 - 0.1 13.4 0.0 0.31 11.9 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EER26544.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Per1 PF04080.8 EER26545.1 - 1.4e-108 362.3 8.6 1.8e-108 362.0 6.0 1.0 1 0 0 1 1 1 1 Per1-like PGM_PMM_I PF02878.11 EER26546.1 - 5.8e-16 58.2 0.3 1e-06 28.3 0.0 3.3 3 1 1 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EER26546.1 - 4.4e-15 55.8 0.3 5.8e-14 52.2 0.0 2.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EER26546.1 - 2e-11 43.7 0.4 5.8e-11 42.2 0.3 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EER26546.1 - 0.00085 19.3 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DEAD PF00270.24 EER26547.1 - 1.1e-46 158.4 0.0 1.7e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER26547.1 - 3.1e-25 87.8 0.0 6.9e-25 86.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER26547.1 - 0.00041 20.2 0.0 0.0022 17.8 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Brix PF04427.13 EER26548.1 - 1.9e-56 190.7 1.3 2.7e-56 190.2 0.9 1.2 1 0 0 1 1 1 1 Brix domain DUF2681 PF10883.3 EER26548.1 - 0.053 13.7 3.2 0.15 12.3 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Lum_binding PF00677.12 EER26550.1 - 2.9e-38 129.6 0.4 9.3e-21 73.5 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain PHB_acc PF05233.8 EER26550.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PHB accumulation regulatory domain CoA_transf_3 PF02515.12 EER26551.1 - 2.9e-60 202.7 0.0 4.3e-60 202.2 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III PHD PF00628.24 EER26552.1 - 2.6e-08 33.4 7.5 4.5e-08 32.6 5.2 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 EER26552.1 - 0.028 14.1 2.4 0.057 13.1 1.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EER26552.1 - 0.14 11.4 9.1 0.035 13.4 3.0 2.3 2 1 0 2 2 2 0 PHD-finger FYVE_2 PF02318.11 EER26552.1 - 0.21 11.4 1.1 0.35 10.7 0.8 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger DUF164 PF02591.10 EER26552.1 - 0.29 10.9 2.9 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Putative zinc ribbon domain MSP1_C PF07462.6 EER26552.1 - 0.44 8.8 6.8 0.037 12.4 0.5 2.0 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus Band_7 PF01145.20 EER26553.1 - 2.4e-23 82.9 4.0 4.9e-23 81.9 2.8 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EER26553.1 - 0.035 13.6 0.1 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Perilipin PF03036.11 EER26554.1 - 0.00059 18.7 0.0 0.00073 18.4 0.0 1.2 1 0 0 1 1 1 1 Perilipin family Ribosomal_L27e PF01777.13 EER26555.1 - 8.9e-39 131.5 4.0 1.1e-38 131.1 2.8 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EER26555.1 - 0.00067 19.2 1.2 0.0015 18.1 0.1 2.2 2 0 0 2 2 2 1 KOW motif SMAP PF15477.1 EER26555.1 - 0.15 12.3 2.2 0.34 11.2 1.5 1.6 1 1 0 1 1 1 0 Small acidic protein family TRAM_LAG1_CLN8 PF03798.11 EER26557.1 - 2.1e-49 167.8 17.4 2.1e-49 167.8 12.1 1.4 2 0 0 2 2 2 1 TLC domain SWIB PF02201.13 EER26558.1 - 5.6e-16 57.9 0.0 2.1e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 SWIB/MDM2 domain DUF883 PF05957.8 EER26558.1 - 0.051 13.9 0.3 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) PCI PF01399.22 EER26559.1 - 1.3e-20 73.6 1.0 2.6e-20 72.6 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_12 PF13424.1 EER26559.1 - 9e-07 28.7 12.7 0.0091 15.9 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER26559.1 - 1e-05 24.9 1.8 14 5.7 0.0 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EER26559.1 - 0.00026 20.5 3.2 5.7 6.9 0.0 5.4 4 1 0 5 5 5 1 Tetratricopeptide repeat DDRGK PF09756.4 EER26559.1 - 0.00032 20.1 0.2 0.00064 19.1 0.1 1.5 1 0 0 1 1 1 1 DDRGK domain HTH_Crp_2 PF13545.1 EER26559.1 - 0.0016 18.1 0.2 0.55 10.0 0.1 3.1 2 1 1 3 3 3 1 Crp-like helix-turn-helix domain PCI_Csn8 PF10075.4 EER26559.1 - 0.0017 18.1 0.6 0.0045 16.7 0.2 1.9 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EER26559.1 - 0.002 17.9 1.5 60 3.9 0.0 5.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EER26559.1 - 0.0024 17.4 0.7 29 4.4 0.0 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EER26559.1 - 0.0052 17.4 8.8 0.69 10.6 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EER26559.1 - 0.022 15.3 5.0 9.2 7.2 0.0 5.2 5 1 0 5 5 5 0 Tetratricopeptide repeat ABC_membrane_2 PF06472.10 EER26559.1 - 0.025 13.6 0.2 0.045 12.8 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region 2 Prefoldin_2 PF01920.15 EER26559.1 - 0.071 12.8 0.7 0.24 11.2 0.5 1.9 1 0 0 1 1 1 0 Prefoldin subunit TPR_6 PF13174.1 EER26559.1 - 0.15 12.5 8.3 1.3 9.5 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EER26559.1 - 2.4 8.0 10.3 0.075 12.9 0.3 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 EER26560.1 - 5.6e-36 121.1 6.7 2.9e-08 33.2 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Sof1 PF04158.9 EER26560.1 - 8.2e-30 102.6 14.1 1.4e-29 101.9 9.8 1.4 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 EER26560.1 - 0.00088 19.0 0.0 8.6 6.1 0.0 3.8 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EER26560.1 - 0.0067 16.1 0.3 0.052 13.2 0.0 2.2 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF3022 PF11226.3 EER26560.1 - 0.12 12.2 0.9 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) adh_short PF00106.20 EER26561.1 - 7.1e-23 81.3 0.3 1.1e-22 80.7 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER26561.1 - 1.1e-13 51.5 0.0 1.4e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER26561.1 - 3.1e-08 33.4 0.3 5.8e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EER26561.1 - 0.00033 19.8 0.2 0.00071 18.7 0.2 1.5 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Bacteriocin_IId PF09221.5 EER26561.1 - 1.4 8.9 8.4 0.46 10.4 0.3 3.2 3 0 0 3 3 3 0 Bacteriocin class IId cyclical uberolysin-like COG7 PF10191.4 EER26562.1 - 0.013 13.4 0.0 0.048 11.5 0.0 1.8 3 0 0 3 3 3 0 Golgi complex component 7 (COG7) CHDCT2 PF08074.6 EER26562.1 - 0.021 14.5 0.5 0.09 12.4 0.0 2.2 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain FUSC PF04632.7 EER26562.1 - 9.3 4.5 7.2 9.6 4.4 0.9 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family RNA_pol_Rpb4 PF03874.11 EER26563.1 - 1.6e-07 31.3 2.8 0.0029 17.5 0.0 2.4 2 1 0 2 2 2 2 RNA polymerase Rpb4 Pox_Ag35 PF03286.9 EER26563.1 - 0.13 11.7 2.2 0.21 11.0 0.1 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Nop PF01798.13 EER26564.1 - 1.5e-54 183.3 0.9 3.9e-54 182.0 0.6 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EER26564.1 - 7.1e-27 92.9 0.1 1.3e-26 92.0 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EER26564.1 - 3.3e-23 81.6 2.3 3.3e-23 81.6 1.6 2.6 3 0 0 3 3 3 1 NOP5NT (NUC127) domain vATP-synt_AC39 PF01992.11 EER26565.1 - 3.2e-112 375.0 0.0 3.6e-112 374.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Pribosyl_synth PF14572.1 EER26566.1 - 2.4e-38 131.7 1.8 6.2e-34 117.3 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EER26566.1 - 1.4e-32 111.8 0.0 5.4e-32 109.9 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EER26566.1 - 5.3e-11 42.3 0.1 1.8e-10 40.6 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EER26566.1 - 0.0033 16.6 0.2 0.0054 15.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ubiquitin PF00240.18 EER26567.1 - 0.00063 19.0 0.0 0.00096 18.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EER26567.1 - 0.057 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PIG-H PF10181.4 EER26568.1 - 4.5e-28 96.6 0.4 8.8e-28 95.7 0.3 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 EER26569.1 - 2.3e-30 105.0 0.0 1.1e-22 80.4 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase Amidoligase_2 PF12224.3 EER26570.1 - 1.2e-10 41.4 0.0 3.7e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Putative amidoligase enzyme Ribosomal_S2 PF00318.15 EER26571.1 - 3.6e-44 150.4 0.0 4e-23 81.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EER26572.1 - 2.6e-17 62.3 0.2 6.1e-17 61.1 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 CorA PF01544.13 EER26573.1 - 1.6e-08 33.9 9.8 3.8e-07 29.4 3.6 2.3 1 1 1 2 2 2 2 CorA-like Mg2+ transporter protein 7TM_GPCR_Srw PF10324.4 EER26573.1 - 0.007 15.5 2.9 0.012 14.7 2.0 1.4 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srw DEAD PF00270.24 EER26575.1 - 9.8e-37 126.0 0.0 9.3e-36 122.8 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER26575.1 - 3.9e-20 71.4 0.0 9.7e-20 70.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EER26575.1 - 1.2e-19 69.6 0.0 2.1e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EER26575.1 - 0.0013 18.5 2.5 0.0072 16.1 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EER26575.1 - 0.054 13.2 0.2 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain BBS1 PF14779.1 EER26575.1 - 0.18 10.7 4.1 0.33 9.8 2.8 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 AAA_22 PF13401.1 EER26575.1 - 0.35 11.0 2.4 1.3 9.1 0.2 2.6 2 1 0 2 2 2 0 AAA domain SR-25 PF10500.4 EER26575.1 - 1.9 7.8 23.5 3.4 7.0 16.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CTP_transf_1 PF01148.15 EER26576.1 - 7.6e-15 55.2 6.7 1.2e-14 54.6 4.6 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family XPG_I PF00867.13 EER26577.1 - 1.7e-18 66.4 0.0 4.5e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EER26577.1 - 1.4e-08 34.9 0.0 3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Actin PF00022.14 EER26578.1 - 4.3e-21 74.8 0.0 9.5e-20 70.3 0.0 2.8 2 1 0 2 2 2 1 Actin Aldose_epim PF01263.15 EER26580.1 - 1.6e-48 165.3 1.3 2.2e-48 164.9 0.9 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase CobU PF02283.11 EER26581.1 - 0.2 11.0 1.2 0.49 9.7 0.8 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Pkinase PF00069.20 EER26582.1 - 2.4e-10 40.0 0.0 4.3e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER26582.1 - 1.6e-07 30.6 0.0 2.7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_72 PF03198.9 EER26583.1 - 2.4e-84 283.0 0.0 4.5e-84 282.1 0.0 1.3 1 1 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EER26583.1 - 0.00094 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sds3 PF08598.6 EER26585.1 - 9.7e-48 162.4 5.6 3.7e-47 160.5 3.9 1.9 1 1 0 1 1 1 1 Sds3-like Pkinase PF00069.20 EER26586.1 - 0.053 12.6 0.0 0.078 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.12 EER26586.1 - 0.14 11.2 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase CFEM PF05730.6 EER26589.1 - 6.8e-05 22.6 3.3 6.8e-05 22.6 2.3 2.4 2 0 0 2 2 2 1 CFEM domain HTH_23 PF13384.1 EER26590.1 - 0.00068 19.1 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.1 EER26590.1 - 0.0088 15.5 0.1 0.09 12.3 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EER26590.1 - 0.03 13.7 0.0 0.089 12.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 Sigma70_r4 PF04545.11 EER26590.1 - 0.037 13.3 0.0 0.74 9.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.13 EER26590.1 - 0.043 13.8 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposase HTH_28 PF13518.1 EER26590.1 - 0.047 13.6 0.1 0.25 11.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain DUF605 PF04652.11 EER26590.1 - 4.3 6.6 12.9 5 6.4 8.9 1.1 1 0 0 1 1 1 0 Vta1 like DUF2752 PF10825.3 EER26592.1 - 0.0083 16.1 1.2 0.013 15.5 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) Otopetrin PF03189.8 EER26592.1 - 0.1 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Otopetrin BTB PF00651.26 EER26593.1 - 3.3e-07 30.2 0.0 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EER26593.1 - 0.037 14.1 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain DUF3756 PF12581.3 EER26594.1 - 0.12 12.0 0.2 0.53 10.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3756) Peptidase_S24 PF00717.18 EER26595.1 - 2.1e-08 33.6 0.1 4.1e-08 32.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.21 EER26596.1 - 5.1e-42 142.6 0.0 5.8e-42 142.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER26596.1 - 2.3e-10 40.3 0.0 3.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EER26596.1 - 0.0067 16.3 0.0 0.0084 15.9 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EER26596.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.13 EER26597.1 - 1.2e-36 126.2 0.0 1.1e-35 123.0 0.0 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain BCS1_N PF08740.6 EER26599.1 - 5.9e-52 175.9 0.1 7.9e-52 175.5 0.1 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EER26599.1 - 9.8e-18 64.6 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EER26599.1 - 1.6e-05 25.2 0.0 0.0042 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER26599.1 - 5.3e-05 24.0 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER26599.1 - 8.1e-05 22.6 0.0 0.00064 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EER26599.1 - 0.00098 19.2 0.0 0.0055 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EER26599.1 - 0.0011 17.8 0.0 0.0026 16.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EER26599.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EER26599.1 - 0.0025 17.4 0.0 0.083 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EER26599.1 - 0.0078 15.6 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER26599.1 - 0.0088 15.7 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EER26599.1 - 0.015 15.0 0.6 0.086 12.5 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain ABC_tran PF00005.22 EER26599.1 - 0.016 15.4 0.0 0.037 14.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EER26599.1 - 0.022 14.2 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EER26599.1 - 0.03 14.4 0.0 0.084 13.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 EER26599.1 - 0.081 12.1 0.0 0.33 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EER26599.1 - 0.13 11.3 0.0 0.33 10.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 EER26599.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 KaiC Lactamase_B_2 PF12706.2 EER26600.1 - 7.2e-39 133.3 0.2 9.3e-39 132.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EER26600.1 - 3.9e-11 42.9 0.0 1.3e-10 41.2 0.0 1.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EER26600.1 - 1.1e-05 25.1 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Cpn60_TCP1 PF00118.19 EER26601.1 - 5.7e-163 543.0 0.3 6.5e-163 542.8 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EER26602.1 - 1.1e-44 151.3 10.1 1.5e-44 150.9 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) eIF-3_zeta PF05091.7 EER26602.1 - 0.035 12.7 2.0 0.038 12.6 1.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RNA_polI_A34 PF08208.6 EER26602.1 - 0.056 13.1 13.2 0.076 12.6 9.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 U79_P34 PF03064.11 EER26602.1 - 0.065 12.7 8.2 0.1 12.1 5.7 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 EER26602.1 - 0.18 11.6 5.6 0.25 11.1 3.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNase_H2-Ydr279 PF09468.5 EER26602.1 - 0.25 10.4 6.2 0.27 10.3 4.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Gly-zipper_OmpA PF13436.1 EER26602.1 - 0.57 9.8 4.6 2.8 7.6 0.7 2.1 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain PhoD PF09423.5 EER26603.1 - 6.7e-146 486.4 0.1 8.2e-146 486.1 0.1 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase zf-PARP PF00645.13 EER26604.1 - 2.3e-18 66.1 0.6 3.8e-18 65.5 0.4 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF4608 PF15381.1 EER26604.1 - 0.093 12.8 0.4 0.25 11.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) Kinesin PF00225.18 EER26605.1 - 2.3e-56 190.9 0.0 3.4e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain bZIP_2 PF07716.10 EER26605.1 - 0.0001 22.0 0.7 0.00042 20.0 0.5 2.1 1 0 0 1 1 1 1 Basic region leucine zipper AAA_33 PF13671.1 EER26605.1 - 0.0028 17.5 0.1 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 EER26605.1 - 0.055 11.9 2.6 0.09 11.2 1.8 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EER26605.1 - 3.8 7.0 19.2 6.4 6.3 0.4 2.3 1 1 1 2 2 2 0 IncA protein TPR_11 PF13414.1 EER26606.1 - 0.00035 20.1 2.3 3.1 7.5 0.4 3.9 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 EER26606.1 - 0.0043 17.5 1.6 7.3 7.5 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER26606.1 - 0.027 14.0 10.6 1.7 8.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EER26606.1 - 0.52 10.3 12.0 2 8.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EER26607.1 - 2.1e-150 500.8 0.0 2.8e-150 500.4 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EER26607.1 - 1.3e-08 34.3 0.8 0.0032 17.0 0.0 3.1 4 0 0 4 4 4 2 TPR repeat TPR_2 PF07719.12 EER26607.1 - 1.3e-07 30.9 2.5 0.0088 15.8 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EER26607.1 - 3.3e-07 29.6 0.3 0.14 11.8 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER26607.1 - 1e-06 28.0 0.1 0.27 11.0 0.0 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EER26607.1 - 9.3e-06 25.4 1.7 1.2 9.1 0.1 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EER26607.1 - 1.1e-05 25.5 0.3 0.039 14.0 0.0 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EER26607.1 - 1.5e-05 25.1 2.7 6.3 7.7 0.0 5.3 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EER26607.1 - 2.7e-05 24.4 0.1 0.12 12.7 0.0 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EER26607.1 - 0.0001 22.0 0.2 0.1 12.4 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER26607.1 - 0.00015 22.3 0.1 0.28 11.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EER26607.1 - 0.00066 19.2 1.8 4.1 7.4 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat ERCC4 PF02732.10 EER26609.1 - 6.5e-30 103.7 0.0 1e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain E1-E2_ATPase PF00122.15 EER26610.1 - 3.7e-51 173.3 0.0 1.4e-50 171.4 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HMA PF00403.21 EER26610.1 - 4.6e-39 132.3 0.8 2.3e-11 43.6 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EER26610.1 - 1.9e-34 119.9 0.3 3.4e-34 119.1 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EER26610.1 - 2e-20 73.8 0.0 3.5e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER26610.1 - 2.1e-05 24.2 2.0 0.0083 15.7 0.3 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase TFIIB PF00382.14 EER26611.1 - 2.9e-33 113.4 6.4 4.5e-18 64.8 0.1 3.3 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EER26611.1 - 3.8e-26 91.1 0.0 3.8e-26 91.1 0.0 3.1 4 0 0 4 4 4 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EER26611.1 - 0.00023 20.3 2.5 0.00054 19.2 1.7 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EER26611.1 - 0.00062 19.3 0.1 0.49 9.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 EER26611.1 - 0.018 14.4 0.2 0.037 13.5 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Nucleoplasmin PF03066.10 EER26611.1 - 0.04 13.4 2.4 0.092 12.2 1.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin IBR PF01485.16 EER26611.1 - 0.048 13.5 1.1 0.1 12.4 0.8 1.5 1 0 0 1 1 1 0 IBR domain Metallophos PF00149.23 EER26612.1 - 5.1e-14 52.1 2.6 1.2e-13 50.9 1.8 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER26612.1 - 2.8e-05 23.9 0.0 6.7e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TPT PF03151.11 EER26614.1 - 1.7e-26 92.6 11.9 1.7e-26 92.6 8.2 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EER26614.1 - 1.6e-09 37.1 19.2 1.9e-08 33.5 13.3 2.0 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EER26614.1 - 0.05 13.6 27.7 0.19 11.7 5.7 2.6 3 0 0 3 3 3 0 EamA-like transporter family DUF914 PF06027.7 EER26614.1 - 0.075 11.8 13.7 0.17 10.7 9.5 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) APH PF01636.18 EER26615.1 - 9.1e-15 55.0 0.1 1.1e-14 54.7 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EER26615.1 - 0.13 11.2 0.1 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Y1_Tnp PF01797.11 EER26617.1 - 0.033 14.0 0.0 0.038 13.8 0.0 1.1 1 0 0 1 1 1 0 Transposase IS200 like NAD_binding_8 PF13450.1 EER26618.1 - 1.4e-09 37.7 0.0 3.8e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EER26618.1 - 2.8e-06 26.6 0.0 2.8e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EER26618.1 - 2e-05 24.7 0.5 0.00013 22.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER26618.1 - 0.022 14.6 0.0 0.068 13.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER26618.1 - 0.023 14.4 0.4 0.48 10.1 0.0 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EER26618.1 - 0.029 13.4 0.1 0.049 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 EER26618.1 - 0.037 12.9 0.0 0.06 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EER26618.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EER26618.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EER26618.1 - 0.19 10.1 0.1 0.28 9.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pkinase PF00069.20 EER26619.1 - 1.1e-64 218.1 0.0 1.5e-64 217.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26619.1 - 7e-33 113.7 0.0 1.2e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER26619.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EER26619.1 - 0.0047 16.0 0.0 0.0077 15.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EER26619.1 - 0.022 13.7 0.0 0.32 9.9 0.0 2.1 2 0 0 2 2 2 0 Kinase-like YukC PF10140.4 EER26619.1 - 0.14 10.6 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC tRNA-synt_2b PF00587.20 EER26621.1 - 4.3e-22 78.5 0.0 6.3e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EER26621.1 - 2.6e-07 30.6 4.2 6.3e-07 29.3 2.9 1.6 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain HCaRG PF07258.9 EER26621.1 - 0.028 13.9 2.6 0.054 13.0 1.8 1.4 1 0 0 1 1 1 0 HCaRG protein AAA_13 PF13166.1 EER26621.1 - 0.036 12.5 2.4 0.053 11.9 1.7 1.1 1 0 0 1 1 1 0 AAA domain Mnd1 PF03962.10 EER26621.1 - 0.064 12.9 3.3 0.12 11.9 2.3 1.4 1 0 0 1 1 1 0 Mnd1 family Prominin PF05478.6 EER26621.1 - 0.1 10.1 0.1 0.3 8.5 0.0 1.6 1 1 1 2 2 2 0 Prominin DUF4200 PF13863.1 EER26621.1 - 0.54 10.2 3.7 0.87 9.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF342 PF03961.8 EER26621.1 - 1.4 7.2 3.6 2 6.7 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Cytochrom_B561 PF03188.11 EER26622.1 - 5.7e-15 55.3 3.7 5.7e-15 55.3 2.6 2.0 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4153 PF13687.1 EER26622.1 - 0.0039 16.7 8.4 0.009 15.5 5.9 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4153) Frag1 PF10277.4 EER26622.1 - 0.0047 16.4 3.2 0.0075 15.7 2.2 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3999 PF13163.1 EER26622.1 - 0.025 13.5 0.2 0.03 13.2 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3999) DUF1282 PF06930.7 EER26622.1 - 0.042 13.4 9.7 0.64 9.6 6.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) PepSY_TM_2 PF13703.1 EER26622.1 - 0.054 13.6 6.8 2.8 8.1 0.4 3.4 1 1 2 3 3 3 0 PepSY-associated TM helix Bax1-I PF01027.15 EER26622.1 - 0.11 12.1 7.6 0.17 11.4 5.3 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Ni_hydr_CYTB PF01292.15 EER26622.1 - 0.31 10.4 8.3 2.2 7.6 5.8 2.4 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Tetraspannin PF00335.15 EER26622.1 - 0.63 9.2 3.3 2.1 7.5 0.4 2.1 1 1 1 2 2 2 0 Tetraspanin family Cytochrom_B_N PF00033.14 EER26622.1 - 0.65 9.3 9.7 1.3 8.3 3.8 2.7 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF4064 PF13273.1 EER26622.1 - 0.93 9.6 7.8 0.12 12.4 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) COX15-CtaA PF02628.10 EER26622.1 - 0.98 8.2 13.5 13 4.5 9.4 2.2 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein DUF2306 PF10067.4 EER26622.1 - 1.2 9.3 9.0 0.84 9.7 0.5 2.8 2 1 0 3 3 3 0 Predicted membrane protein (DUF2306) AzlD PF05437.7 EER26622.1 - 1.6 8.7 7.4 0.25 11.2 1.3 2.1 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF308 PF03729.8 EER26622.1 - 1.8 8.5 7.4 7.5 6.6 2.5 2.5 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Allantoicase PF03561.10 EER26623.1 - 1.1e-87 291.2 0.0 1.1e-48 164.5 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat HATPase_c PF02518.21 EER26624.1 - 8.6e-22 76.9 0.1 2.9e-21 75.2 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EER26624.1 - 2.5e-21 75.7 0.1 8.2e-21 74.1 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EER26624.1 - 1.1e-17 63.8 0.0 3.5e-17 62.1 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EER26624.1 - 2.9e-10 40.0 0.4 0.0087 16.1 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 EER26624.1 - 1.8e-09 37.9 0.0 1.4e-06 28.5 0.0 3.0 2 0 0 2 2 2 2 PAS domain PAS_4 PF08448.5 EER26624.1 - 9.2e-06 25.6 0.0 3.6e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EER26624.1 - 0.0037 17.0 0.0 2.7 7.8 0.0 3.2 3 0 0 3 3 3 2 PAS fold HATPase_c PF02518.21 EER26625.1 - 3.2e-28 97.6 0.1 7.4e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EER26625.1 - 1.2e-20 73.5 0.1 2.8e-20 72.4 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EER26625.1 - 3.8e-19 68.4 0.2 1.6e-18 66.4 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EER26625.1 - 6.4e-10 39.3 0.5 1.6e-08 34.7 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain GAF PF01590.21 EER26625.1 - 1.4e-09 38.2 0.0 5.3e-09 36.3 0.0 2.1 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EER26625.1 - 2e-09 38.0 0.0 4.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EER26625.1 - 6.2e-07 28.8 0.0 2.9e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 EER26625.1 - 1.3e-06 28.5 0.0 3.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 EER26625.1 - 0.0019 17.8 0.0 0.0051 16.4 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NB-ARC PF00931.17 EER26625.1 - 0.0023 16.8 0.0 0.83 8.4 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain ArgK PF03308.11 EER26625.1 - 0.023 13.4 0.0 0.046 12.4 0.0 1.4 1 0 0 1 1 1 0 ArgK protein GTP_cyclohydroI PF01227.17 EER26625.1 - 0.037 13.2 0.6 0.34 10.1 0.3 2.3 2 0 0 2 2 2 0 GTP cyclohydrolase I KxDL PF10241.4 EER26626.1 - 4.3e-34 116.2 0.8 5.4e-34 115.9 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein AAA PF00004.24 EER26627.1 - 6.5e-53 178.4 0.0 1e-38 132.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EER26627.1 - 1.1e-13 50.8 0.0 2.5e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EER26627.1 - 4.2e-11 42.3 0.1 4.3e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EER26627.1 - 1.5e-09 38.0 0.3 0.0005 20.2 0.1 3.6 2 2 0 2 2 2 2 AAA domain TIP49 PF06068.8 EER26627.1 - 1.9e-08 33.4 0.0 0.0038 16.0 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 EER26627.1 - 2.1e-08 34.9 0.0 0.0017 19.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EER26627.1 - 2.8e-08 33.7 0.0 0.015 15.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EER26627.1 - 2.9e-08 33.9 0.0 0.003 17.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EER26627.1 - 6.4e-08 32.4 0.1 0.0018 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EER26627.1 - 9.5e-08 31.6 1.6 0.015 15.0 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_18 PF13238.1 EER26627.1 - 1.7e-07 31.5 0.2 0.0028 17.9 0.0 3.0 4 0 0 4 4 2 2 AAA domain Mg_chelatase PF01078.16 EER26627.1 - 1.9e-07 30.4 0.1 0.0042 16.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EER26627.1 - 2.2e-07 30.9 0.0 2.7e-05 24.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EER26627.1 - 3.6e-07 29.4 0.0 0.024 13.6 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EER26627.1 - 4.8e-07 29.7 0.0 0.027 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EER26627.1 - 1.9e-06 27.9 0.0 0.028 14.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EER26627.1 - 2.6e-06 26.9 0.1 0.036 13.4 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_24 PF13479.1 EER26627.1 - 6.4e-06 25.9 0.2 0.12 11.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EER26627.1 - 8.8e-06 24.9 0.0 0.05 12.6 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EER26627.1 - 4e-05 23.1 2.0 0.38 10.1 0.0 3.6 2 2 2 4 4 4 2 AAA domain KaiC PF06745.8 EER26627.1 - 5.6e-05 22.3 0.2 0.022 13.8 0.1 2.4 2 0 0 2 2 2 1 KaiC NACHT PF05729.7 EER26627.1 - 6.1e-05 22.7 0.3 0.063 12.9 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.6 EER26627.1 - 7.8e-05 22.2 0.0 0.23 11.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EER26627.1 - 9.4e-05 21.7 0.0 0.19 10.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.17 EER26627.1 - 0.00014 20.8 0.1 0.28 10.0 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.22 EER26627.1 - 0.0002 21.7 0.1 0.019 15.2 0.1 2.4 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.1 EER26627.1 - 0.00048 20.1 0.0 0.62 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EER26627.1 - 0.0005 19.5 0.0 0.48 9.8 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EER26627.1 - 0.00059 19.6 0.2 4.8 6.8 0.0 3.3 2 1 1 3 3 3 0 Archaeal ATPase AAA_11 PF13086.1 EER26627.1 - 0.0015 18.1 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 EER26627.1 - 0.002 17.1 0.0 0.41 9.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.5 EER26627.1 - 0.0024 17.1 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 UPF0079 PF02367.12 EER26627.1 - 0.0026 17.3 0.0 0.56 9.8 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EER26627.1 - 0.0062 16.5 0.1 7 6.7 0.0 3.2 3 1 0 3 3 2 0 Sigma-54 interaction domain DEAD PF00270.24 EER26627.1 - 0.0063 16.0 0.1 16 4.9 0.0 4.1 3 1 1 4 4 4 0 DEAD/DEAH box helicase Parvo_NS1 PF01057.12 EER26627.1 - 0.012 14.5 0.0 0.42 9.4 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EER26627.1 - 0.015 14.8 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EER26627.1 - 0.024 14.1 0.1 2.3 7.6 0.0 2.8 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain ResIII PF04851.10 EER26627.1 - 0.034 13.9 0.0 9.8 5.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EER26627.1 - 0.059 13.0 0.1 14 5.3 0.0 2.9 2 0 0 2 2 2 0 NTPase Zot PF05707.7 EER26627.1 - 0.068 12.6 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) cobW PF02492.14 EER26627.1 - 0.082 12.3 0.1 4.8 6.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EER26627.1 - 0.095 11.5 0.0 6.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 EER26627.1 - 0.12 11.9 0.0 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Methyltransf_31 PF13847.1 EER26629.1 - 7.8e-10 38.5 0.1 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EER26629.1 - 8.6e-09 34.9 0.1 1.5e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EER26629.1 - 1.7e-07 31.7 0.1 5.2e-07 30.2 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER26629.1 - 2.3e-07 31.2 0.0 5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER26629.1 - 3.6e-06 26.9 0.0 6.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER26629.1 - 1.5e-05 24.4 0.2 3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EER26629.1 - 0.00013 21.7 0.1 0.00035 20.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EER26629.1 - 0.00032 19.5 0.0 0.00047 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EER26629.1 - 0.0021 18.4 0.1 0.0049 17.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Toxin_64 PF15542.1 EER26629.1 - 0.019 15.5 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 Putative toxin 64 Methyltransf_12 PF08242.7 EER26629.1 - 0.026 14.9 0.0 0.085 13.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EER26629.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Rootletin PF15035.1 EER26629.1 - 0.048 13.6 0.1 0.088 12.7 0.0 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Methyltransf_24 PF13578.1 EER26629.1 - 0.097 13.5 0.0 0.3 11.9 0.0 1.9 2 0 0 2 2 1 0 Methyltransferase domain PCMT PF01135.14 EER26629.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pox_A_type_inc PF04508.7 EER26629.1 - 0.49 10.3 3.6 1.4 8.9 2.5 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Mo25 PF08569.6 EER26630.1 - 6.9e-125 416.5 0.1 7.7e-125 416.3 0.1 1.0 1 0 0 1 1 1 1 Mo25-like TPP_enzyme_N PF02776.13 EER26631.1 - 4.4e-43 146.7 0.0 1.2e-42 145.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EER26631.1 - 7.2e-19 67.8 0.0 2.6e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EER26631.1 - 2.1e-17 63.1 0.0 4.3e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DXP_synthase_N PF13292.1 EER26631.1 - 0.024 13.5 0.0 0.044 12.7 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase RabGAP-TBC PF00566.13 EER26632.1 - 1.8e-35 122.3 0.0 2.8e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 EER26634.1 - 9.8e-20 70.6 0.1 4.5e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DIL PF01843.14 EER26634.1 - 1.6e-19 69.6 0.6 3.4e-12 46.1 0.1 2.6 2 0 0 2 2 2 2 DIL domain Ank PF00023.25 EER26634.1 - 1.7e-14 52.7 0.0 3.7e-06 26.4 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EER26634.1 - 3.1e-12 46.3 0.0 1.7e-07 31.2 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER26634.1 - 1.8e-08 33.8 0.2 0.019 15.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EER26634.1 - 4.1e-08 33.5 0.1 0.00028 21.3 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) RasGEF PF00617.14 EER26635.1 - 2.7e-41 141.3 0.3 5.3e-41 140.4 0.2 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EER26635.1 - 2.3e-14 53.3 0.1 5.1e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Arginosuc_synth PF00764.14 EER26636.1 - 8.2e-151 502.4 0.0 9.7e-151 502.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EER26636.1 - 0.00017 21.1 0.0 0.00023 20.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EER26636.1 - 0.0045 16.3 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EER26636.1 - 0.028 12.9 0.0 0.04 12.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase MAD PF05557.8 EER26637.1 - 6.6e-55 186.5 68.7 1.8e-45 155.2 47.2 2.1 2 0 0 2 2 2 2 Mitotic checkpoint protein TBPIP PF07106.8 EER26637.1 - 0.012 15.1 2.4 0.012 15.1 1.6 7.6 2 2 5 7 7 7 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Peptidase_M20 PF01546.23 EER26638.1 - 4.5e-30 104.5 0.3 6e-30 104.1 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EER26638.1 - 1.2e-18 66.8 0.1 3e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain TFIIA_gamma_C PF02751.9 EER26638.1 - 0.014 15.1 0.1 0.04 13.7 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit muHD PF10291.4 EER26639.1 - 6.9e-71 238.4 0.1 1.1e-70 237.7 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EER26639.1 - 4.8e-10 39.4 0.5 3.1e-09 36.8 0.0 2.6 4 0 0 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain NUFIP1 PF10453.4 EER26639.1 - 0.2 11.2 1.7 0.29 10.6 0.2 2.0 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Pkinase PF00069.20 EER26640.1 - 1.5e-43 148.8 0.0 2e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26640.1 - 2e-16 59.8 0.0 3e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER26640.1 - 8.8e-08 32.1 0.1 0.00013 21.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EER26640.1 - 0.0013 17.7 0.0 0.002 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like SH3_9 PF14604.1 EER26641.1 - 3e-09 36.3 0.0 5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EER26641.1 - 1.9e-06 27.1 0.0 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EER26641.1 - 4.4e-05 22.8 0.0 9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SCF PF02404.10 EER26641.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Stem cell factor DUF4366 PF14283.1 EER26641.1 - 9.1 5.6 6.1 0.83 9.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) OPT PF03169.10 EER26642.1 - 2.4e-166 554.8 11.8 3e-166 554.4 8.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Rav1p_C PF12234.3 EER26643.1 - 2.6e-271 901.3 1.1 1.7e-270 898.6 1.1 1.8 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.27 EER26643.1 - 0.00023 20.8 5.0 0.37 10.7 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Sfi1 PF08457.5 EER26644.1 - 8.5e-149 496.5 91.1 7.7e-148 493.4 57.5 2.0 1 1 1 2 2 2 2 Sfi1 spindle body protein tRNA-synt_1 PF00133.17 EER26645.1 - 4e-221 735.1 0.0 8e-221 734.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EER26645.1 - 7.7e-26 90.6 0.0 2e-25 89.3 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EER26645.1 - 6.7e-17 61.2 0.0 6.1e-08 31.7 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EER26645.1 - 0.054 12.6 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.9 EER26646.1 - 4.4e-112 373.8 0.0 2.9e-111 371.1 0.0 2.1 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EER26646.1 - 3.5e-08 33.4 21.9 3.5e-08 33.4 15.2 3.2 1 1 2 3 3 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Filament PF00038.16 EER26646.1 - 8.1e-05 22.2 40.4 8.9e-05 22.0 25.0 2.2 1 1 0 1 1 1 1 Intermediate filament protein DUF2435 PF10363.4 EER26646.1 - 0.0024 17.7 0.1 11 6.0 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF2435) Myosin_tail_1 PF01576.14 EER26646.1 - 0.11 10.1 47.3 0.23 9.1 32.8 1.5 1 1 0 1 1 1 0 Myosin tail Tropomyosin PF00261.15 EER26646.1 - 0.19 10.8 44.3 0.074 12.1 21.9 2.8 1 1 1 2 2 2 0 Tropomyosin LepA_C PF06421.7 EER26646.1 - 0.2 11.5 1.8 0.42 10.5 0.2 2.3 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus Lectin_N PF03954.9 EER26646.1 - 0.58 9.5 8.2 0.17 11.3 0.8 3.0 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DUF3584 PF12128.3 EER26646.1 - 0.69 7.1 35.5 1.1 6.4 24.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EER26646.1 - 0.9 8.1 32.5 0.056 12.0 3.9 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EER26646.1 - 1.1 9.0 35.7 0.95 9.2 9.7 3.3 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EER26646.1 - 3.7 6.6 5.8 2.2 7.3 0.3 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein XRN_N PF03159.13 EER26647.1 - 6.8e-108 359.5 2.8 1e-107 358.9 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EER26647.1 - 0.046 13.6 1.7 0.089 12.7 1.2 1.5 1 0 0 1 1 1 0 Zinc knuckle EPSP_synthase PF00275.15 EER26648.1 - 3.1e-127 424.5 0.0 4.4e-127 423.9 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EER26648.1 - 1.9e-97 325.2 0.0 3.3e-97 324.4 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EER26648.1 - 6.8e-62 209.0 0.0 1.3e-61 208.1 0.0 1.5 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EER26648.1 - 6.3e-39 133.3 0.1 3.2e-38 131.0 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EER26648.1 - 1.1e-24 86.2 0.0 2.6e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EER26648.1 - 1.6e-10 41.2 0.0 8.7e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EER26648.1 - 4.4e-06 26.1 0.1 2e-05 24.0 0.1 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EER26648.1 - 0.024 15.4 0.0 0.09 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Exo5 PF09810.4 EER26649.1 - 1e-112 376.5 0.0 1.3e-112 376.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EER26649.1 - 0.013 14.9 0.8 5.6 6.2 0.0 2.8 3 0 0 3 3 3 0 PD-(D/E)XK nuclease superfamily Mpv17_PMP22 PF04117.7 EER26650.1 - 1.8e-17 62.7 2.9 2.3e-17 62.3 0.7 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Histone PF00125.19 EER26651.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EER26651.1 - 2.8e-06 27.4 0.0 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EER26651.1 - 0.004 17.1 0.5 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EER26651.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 EER26652.1 - 2.9e-16 59.3 0.3 3.5e-16 59.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EER26652.1 - 6.1e-05 22.8 0.1 8.6e-05 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EER26652.1 - 8.3e-05 22.5 0.1 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EER26652.1 - 0.0001 22.4 0.1 0.00016 21.8 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EER26652.1 - 0.006 15.8 0.0 0.0063 15.8 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EER26652.1 - 0.027 14.1 0.0 0.035 13.8 0.0 1.3 1 1 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 EER26652.1 - 0.13 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit 4HBT_3 PF13622.1 EER26653.1 - 0.19 11.4 3.2 0.22 11.2 2.2 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily TF_Zn_Ribbon PF08271.7 EER26653.1 - 0.23 10.8 1.8 0.42 9.9 1.2 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding PAT1 PF09770.4 EER26653.1 - 2 6.5 11.2 2 6.5 7.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2 PF00096.21 EER26654.1 - 1.2e-09 37.9 13.0 0.0004 20.5 0.9 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER26654.1 - 0.0016 18.5 25.3 0.0032 17.6 0.9 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-BED PF02892.10 EER26654.1 - 0.2 11.4 1.7 0.47 10.2 1.2 1.6 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.1 EER26654.1 - 6.8 7.1 10.9 42 4.6 0.9 4.6 4 0 0 4 4 4 0 Zinc-finger double domain DUF3445 PF11927.3 EER26655.1 - 3.5e-80 268.9 0.0 4.6e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.12 EER26656.1 - 1.2e-61 209.0 10.9 1.4e-61 208.8 7.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PDR_assoc PF08370.6 EER26656.1 - 0.25 10.9 4.4 0.46 10.0 0.2 2.7 2 0 0 2 2 2 0 Plant PDR ABC transporter associated Gar1 PF04410.9 EER26657.1 - 5e-47 159.2 0.8 5e-47 159.2 0.5 2.0 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region PRP3 PF08572.5 EER26658.1 - 1.5e-72 243.5 2.5 3.2e-72 242.5 1.7 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EER26658.1 - 9.4e-38 128.7 0.1 2e-37 127.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EER26659.1 - 1.6e-86 290.0 0.0 9.1e-86 287.5 0.0 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EER26659.1 - 1.4e-62 210.5 0.3 3.8e-62 209.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EER26659.1 - 1.3e-34 119.1 0.0 1.1e-33 116.2 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EER26659.1 - 9.9e-24 84.2 12.9 1.9e-18 66.8 0.0 4.0 2 2 2 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EER26659.1 - 2.7e-16 59.2 0.0 1.2e-15 57.1 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.7 EER26659.1 - 0.32 8.8 21.8 0.01 13.8 10.8 1.5 2 0 0 2 2 2 0 Nop14-like family DUF1227 PF06777.6 EER26660.1 - 1.3e-61 206.6 0.5 2.7e-61 205.5 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EER26660.1 - 7e-52 175.3 0.6 1.1e-51 174.6 0.4 1.3 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EER26660.1 - 3.5e-44 150.6 0.0 7.6e-44 149.6 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EER26660.1 - 0.00052 19.5 0.0 0.065 12.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EER26660.1 - 0.0012 17.6 0.0 0.0044 15.8 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EER26660.1 - 0.0085 15.9 0.0 0.042 13.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EER26660.1 - 0.013 15.0 0.3 0.044 13.3 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EER26660.1 - 0.041 14.0 0.1 3.4 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain zf-RING_2 PF13639.1 EER26661.1 - 1e-08 34.8 7.1 2.9e-08 33.4 4.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EER26661.1 - 1.9e-06 27.8 4.8 2e-06 27.7 1.2 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger FANCL_C PF11793.3 EER26661.1 - 2.8e-05 23.9 7.2 3.5e-05 23.6 3.8 2.0 2 0 0 2 2 2 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EER26661.1 - 2.8e-05 23.8 1.2 9.4e-05 22.1 0.9 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EER26661.1 - 0.00049 19.7 9.6 0.00049 19.7 6.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EER26661.1 - 0.0014 18.3 3.1 0.0014 18.3 2.1 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EER26661.1 - 0.012 15.6 8.9 0.031 14.3 6.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EER26661.1 - 0.023 14.7 7.6 0.045 13.8 5.3 1.5 1 0 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.6 EER26661.1 - 0.13 12.1 1.3 0.42 10.4 0.7 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-RING-like PF08746.6 EER26661.1 - 0.34 10.9 6.7 0.84 9.6 4.6 1.7 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EER26661.1 - 0.8 9.3 5.2 8.2 6.1 3.6 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EER26661.1 - 2.4 7.9 6.7 4.9 6.9 4.7 1.6 1 0 0 1 1 1 0 PHD-finger LCM PF04072.9 EER26662.1 - 8e-24 84.1 0.0 1.3e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SUN PF03856.8 EER26663.1 - 8.1e-83 277.5 11.1 1.1e-82 277.1 7.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Nop14 PF04147.7 EER26663.1 - 0.074 10.9 6.9 0.095 10.6 4.8 1.0 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EER26663.1 - 0.62 8.7 10.7 1 8.0 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.5 EER26663.1 - 1.3 9.3 13.1 2.5 8.3 9.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SDA1 PF05285.7 EER26663.1 - 4.1 6.6 7.8 5.7 6.1 5.4 1.1 1 0 0 1 1 1 0 SDA1 ATP_transf PF09830.4 EER26664.1 - 7e-13 48.1 0.0 1.6e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase zf-C3HC4 PF00097.20 EER26665.1 - 6.8e-10 38.4 4.7 4.4e-09 35.8 3.2 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER26665.1 - 4e-09 36.1 5.2 9.7e-09 34.9 3.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EER26665.1 - 6.7e-08 32.0 4.2 1.5e-07 30.9 2.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER26665.1 - 1.3e-07 31.4 3.4 5.4e-07 29.5 2.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER26665.1 - 5.2e-05 22.8 4.0 0.00013 21.5 2.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EER26665.1 - 7.5e-05 22.5 2.1 7.5e-05 22.5 1.5 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EER26665.1 - 0.0097 15.6 0.7 0.0097 15.6 0.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-SNAP50_C PF12251.3 EER26665.1 - 0.034 13.5 1.0 0.074 12.4 0.7 1.6 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Baculo_RING PF05883.6 EER26665.1 - 0.075 12.8 1.5 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain COG7 PF10191.4 EER26665.1 - 0.076 10.9 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) zf-rbx1 PF12678.2 EER26665.1 - 0.59 10.2 10.8 14 5.8 7.5 2.8 1 1 0 1 1 1 0 RING-H2 zinc finger Kinesin PF00225.18 EER26666.1 - 9.3e-50 169.2 0.0 1.2e-25 89.9 0.0 2.1 2 0 0 2 2 2 2 Kinesin motor domain Zn_clus PF00172.13 EER26667.1 - 0.023 14.5 5.0 0.024 14.5 1.0 2.1 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ist1 PF03398.9 EER26668.1 - 8.3e-30 103.3 0.5 3.3e-14 52.6 0.0 2.2 2 0 0 2 2 2 2 Regulator of Vps4 activity in the MVB pathway PEX11 PF05648.9 EER26669.1 - 0.027 13.7 1.0 0.042 13.1 0.7 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Clat_adaptor_s PF01217.15 EER26670.1 - 3.4e-54 182.4 1.3 4e-54 182.2 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 EER26672.1 - 1.4e-21 77.1 0.2 2.3e-21 76.4 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 EER26673.1 - 7.8e-29 99.3 0.4 8.4e-28 96.0 0.2 2.4 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit Aminotran_1_2 PF00155.16 EER26674.1 - 7.3e-64 215.9 0.0 8.8e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EER26674.1 - 0.0063 14.8 0.0 0.01 14.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Alliinase_C PF04864.8 EER26674.1 - 0.021 13.5 0.0 0.027 13.1 0.0 1.1 1 0 0 1 1 1 0 Allinase Mmp37 PF09139.6 EER26675.1 - 7.6e-138 459.0 0.0 9.2e-138 458.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 BIR PF00653.16 EER26676.1 - 3.7e-42 142.5 7.3 3.3e-22 78.7 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 EER26677.1 - 2.1e-07 30.8 0.3 3.7e-07 30.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EER26677.1 - 4.2e-06 26.7 0.5 7.8e-06 25.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EER26677.1 - 0.0026 17.9 0.4 0.0048 17.1 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EER26677.1 - 0.12 12.5 0.3 0.37 10.9 0.0 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Phage_rep_org_N PF09681.5 EER26677.1 - 0.23 11.0 1.5 0.38 10.3 1.0 1.4 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) F-box-like PF12937.2 EER26678.1 - 0.00021 20.9 0.1 0.00053 19.6 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EER26678.1 - 0.00083 18.9 0.0 0.0033 17.0 0.0 1.9 2 0 0 2 2 2 1 F-box domain AMP-binding PF00501.23 EER26679.1 - 4.7e-51 173.4 0.0 6.2e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER26679.1 - 0.0015 19.4 0.0 0.0037 18.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PHB_acc_N PF07879.6 EER26679.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PHB/PHA accumulation regulator DNA-binding domain DUF605 PF04652.11 EER26680.1 - 1.2 8.4 10.6 1.6 8.0 7.4 1.2 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 EER26681.1 - 9.1e-22 77.7 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER26681.1 - 3.6e-09 36.5 0.0 5.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EER26681.1 - 0.00015 21.6 0.0 0.0002 21.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EER26681.1 - 0.0094 15.1 0.0 0.022 13.8 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EER26681.1 - 0.014 15.3 0.1 0.027 14.4 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EER26681.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DHquinase_II PF01220.14 EER26681.1 - 0.087 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Dehydroquinase class II Eno-Rase_NADH_b PF12242.3 EER26681.1 - 0.14 11.9 0.4 0.28 10.9 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DSBA PF01323.15 EER26682.1 - 1.1e-14 54.4 0.0 1.3e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain AMP-binding PF00501.23 EER26683.1 - 2.4e-91 306.2 0.1 2.9e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER26683.1 - 3.9e-13 50.1 0.2 3.9e-13 50.1 0.2 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain RNA_pol_Rpb5_C PF01191.14 EER26684.1 - 1.1e-34 117.8 0.2 1.9e-34 117.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EER26684.1 - 2.3e-31 108.0 0.0 3.7e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EER26684.1 - 0.0026 17.5 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease FAD-oxidase_C PF02913.14 EER26684.1 - 0.047 13.0 0.1 0.1 11.9 0.1 1.6 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain WEMBL PF05701.6 EER26685.1 - 7.7e-06 24.6 35.8 7.7e-06 24.6 24.8 2.9 2 1 0 2 2 2 1 Weak chloroplast movement under blue light EzrA PF06160.7 EER26685.1 - 0.0015 16.8 8.7 0.0015 16.8 6.0 4.1 2 1 2 4 4 4 1 Septation ring formation regulator, EzrA APG6 PF04111.7 EER26685.1 - 0.0025 16.8 16.7 0.0025 16.8 11.6 3.6 2 1 1 3 3 3 2 Autophagy protein Apg6 DUF2968 PF11180.3 EER26685.1 - 0.0038 16.6 10.2 0.0038 16.6 7.1 5.1 2 1 3 5 5 5 2 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.4 EER26685.1 - 0.0052 16.6 14.1 0.0052 16.6 9.8 4.7 2 2 2 4 4 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 EER26685.1 - 0.011 15.4 6.2 0.011 15.4 4.3 5.4 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EER26685.1 - 1.2 8.3 9.8 4.1 6.5 0.1 3.1 2 1 2 4 4 4 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 EER26685.1 - 1.5 7.1 48.4 0.0042 15.6 12.9 3.1 2 1 1 3 3 3 0 AAA domain DUF1664 PF07889.7 EER26685.1 - 1.7 8.4 24.8 0.19 11.5 1.3 4.5 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) DUF1514 PF07438.6 EER26685.1 - 1.9 8.4 4.0 87 3.1 0.2 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1514) Filament PF00038.16 EER26685.1 - 2.4 7.5 51.2 0.24 10.8 11.7 4.0 2 1 0 3 3 3 0 Intermediate filament protein Baculo_p24 PF05073.7 EER26685.1 - 3.6 7.0 18.1 0.35 10.4 0.7 3.4 3 1 0 3 3 3 0 Baculovirus P24 capsid protein Bacillus_HBL PF05791.6 EER26685.1 - 4.3 6.6 26.3 0.057 12.7 3.4 3.6 2 1 2 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Imm42 PF15601.1 EER26685.1 - 5.3 6.4 8.2 17 4.8 0.0 3.6 4 1 0 4 4 4 0 Immunity protein 42 DUF3584 PF12128.3 EER26685.1 - 7 3.8 51.4 0.0075 13.6 20.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3584) TACC PF05010.9 EER26685.1 - 9.2 5.9 52.0 0.21 11.3 15.7 3.3 2 1 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC) Occludin_ELL PF07303.8 EER26685.1 - 9.3 7.0 35.7 0.12 13.0 1.0 5.3 3 2 3 6 6 6 0 Occludin homology domain CYSTM PF12734.2 EER26686.1 - 8.2e-09 35.3 11.9 8.2e-09 35.3 8.3 5.3 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance Nol1_Nop2_Fmu PF01189.12 EER26687.1 - 1.4e-46 159.1 0.0 1.1e-23 84.0 0.0 3.8 2 1 1 3 3 3 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EER26687.1 - 0.00041 20.3 0.0 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Aldolase_II PF00596.16 EER26688.1 - 3.2e-48 163.7 0.2 4.1e-48 163.4 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DEAD PF00270.24 EER26689.1 - 2.7e-40 137.6 0.0 4.3e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER26689.1 - 5.2e-21 74.3 0.3 1.2e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER26689.1 - 0.00031 20.6 0.2 0.00063 19.6 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2859 PF11072.3 EER26689.1 - 0.02 14.3 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) DUF1253 PF06862.7 EER26689.1 - 0.021 13.2 0.2 0.23 9.8 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EER26689.1 - 0.094 12.4 0.3 0.28 10.9 0.2 1.8 1 0 0 1 1 1 0 Part of AAA domain ADP_ribosyl_GH PF03747.9 EER26690.1 - 1.6e-64 218.4 0.1 1.9e-64 218.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Ank_2 PF12796.2 EER26691.1 - 5.5e-55 183.6 24.0 3e-09 37.0 0.0 13.9 4 4 6 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 EER26691.1 - 3.5e-39 130.6 30.5 0.00017 21.1 0.0 19.4 21 1 0 21 21 21 10 Ankyrin repeat Ank_3 PF13606.1 EER26691.1 - 1.1e-25 87.1 21.6 0.011 15.8 0.0 18.8 24 0 0 24 24 24 6 Ankyrin repeat Ank_4 PF13637.1 EER26691.1 - 6.6e-19 67.9 20.7 0.046 14.2 0.0 13.5 12 3 2 14 14 14 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER26691.1 - 6.9e-14 51.5 13.7 0.00062 19.9 0.0 11.3 12 2 3 15 15 15 5 Ankyrin repeats (many copies) Adenylsucc_synt PF00709.16 EER26692.1 - 3.7e-155 516.7 0.0 4.1e-155 516.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DnaJ PF00226.26 EER26693.1 - 6.3e-20 70.6 0.7 1.5e-19 69.4 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EER26694.1 - 1.8e-28 99.1 0.0 3.2e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26694.1 - 1.9e-08 34.0 10.9 3.2e-08 33.3 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP1_OBG PF01018.17 EER26695.1 - 3.8e-35 120.8 4.3 3e-26 91.9 2.3 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EER26695.1 - 2.6e-21 75.7 0.0 4.3e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EER26695.1 - 2.3e-07 30.2 0.0 4.4e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EER26695.1 - 0.048 13.4 0.0 8.3 6.1 0.0 2.3 1 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 EER26695.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 EER26695.1 - 0.082 11.6 0.1 0.33 9.6 0.0 1.9 2 0 0 2 2 2 0 ArgK protein Arf PF00025.16 EER26695.1 - 0.2 10.8 0.0 0.45 9.7 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family MFS_1 PF07690.11 EER26696.1 - 3.6e-33 114.7 21.6 1.8e-30 105.9 14.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER26696.1 - 5.1e-11 41.8 2.4 5.1e-11 41.8 1.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EER26696.1 - 4e-06 25.4 11.1 0.0003 19.3 0.9 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Cupin_8 PF13621.1 EER26697.1 - 8.1e-34 117.2 0.1 1.4e-33 116.4 0.1 1.4 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EER26697.1 - 4.6e-07 29.4 0.0 0.0012 18.1 0.0 2.4 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EER26697.1 - 0.0086 16.3 0.0 0.051 13.8 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Homeobox_KN PF05920.6 EER26698.1 - 9e-16 57.3 0.5 1.9e-15 56.2 0.4 1.6 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.1 EER26698.1 - 0.00011 22.2 24.4 0.0033 17.6 1.1 4.9 4 1 0 4 4 4 2 C2H2-type zinc finger Homeobox PF00046.24 EER26698.1 - 0.00029 20.3 0.1 0.00062 19.3 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 EER26698.1 - 0.00035 20.7 20.0 0.015 15.5 1.0 4.2 3 1 1 4 4 4 3 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.11 EER26698.1 - 0.0016 18.1 0.0 0.0057 16.4 0.0 2.0 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HA PF03457.9 EER26698.1 - 0.015 15.4 2.5 0.054 13.5 0.1 2.8 3 0 0 3 3 3 0 Helicase associated domain zf-H2C2_2 PF13465.1 EER26698.1 - 0.059 13.6 5.7 5 7.5 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain UQ_con PF00179.21 EER26699.1 - 1.2e-11 44.1 0.1 2.1e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EER26699.1 - 0.0048 16.7 0.1 0.0078 16.0 0.1 1.4 1 0 0 1 1 1 1 RWD domain 2OG-FeII_Oxy_2 PF13532.1 EER26701.1 - 3.9e-34 118.2 0.2 5.1e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EER26701.1 - 1.3e-07 31.4 8.4 2.9e-07 30.3 5.8 1.6 1 0 0 1 1 1 1 GRF zinc finger CUE PF02845.11 EER26701.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 CUE domain 2OG-FeII_Oxy PF03171.15 EER26701.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DinI PF06183.8 EER26701.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 DinI-like family Abhydrolase_6 PF12697.2 EER26702.1 - 1.9e-31 109.7 0.2 2.6e-31 109.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER26702.1 - 1.4e-10 41.0 0.1 2.7e-10 40.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER26702.1 - 0.0053 16.3 0.0 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF3089 PF11288.3 EER26702.1 - 0.03 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) WD40 PF00400.27 EER26703.1 - 1.2e-25 88.3 23.5 2.8e-08 33.3 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat DUF1014 PF06244.7 EER26704.1 - 4.8e-24 84.9 5.8 4.8e-24 84.9 4.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) F-box PF00646.28 EER26705.1 - 7.6e-07 28.6 0.1 2.1e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER26705.1 - 1.5e-06 27.7 0.0 4e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Peptidase_C13 PF01650.13 EER26706.1 - 7.9e-41 140.0 0.0 1.2e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family CDC45 PF02724.9 EER26707.1 - 7.2e-235 780.7 0.0 1.3e-234 779.9 0.0 1.7 1 1 0 1 1 1 1 CDC45-like protein DDRGK PF09756.4 EER26707.1 - 2.5 7.4 13.4 6.2 6.1 9.3 1.6 1 0 0 1 1 1 0 DDRGK domain DUF1330 PF07045.6 EER26708.1 - 0.053 13.3 0.0 0.11 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1330) Acetyltransf_1 PF00583.19 EER26709.1 - 2e-09 37.3 0.0 3.1e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER26709.1 - 1.6e-08 34.5 0.0 2.9e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER26709.1 - 9.3e-06 25.7 0.0 1.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER26709.1 - 0.00016 21.4 0.0 0.00046 20.0 0.0 1.8 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EER26709.1 - 0.0085 15.8 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EER26709.1 - 0.011 15.6 0.0 0.66 9.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EER26710.1 - 3.2e-18 66.2 0.1 5.7e-18 65.4 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER26710.1 - 2.4e-07 30.7 0.0 4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EER26710.1 - 0.00072 19.4 0.1 0.0092 15.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER26710.1 - 0.016 15.1 0.1 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER26710.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Zn_clus PF00172.13 EER26711.1 - 0.0002 21.2 8.2 0.00037 20.3 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_47 PF01532.15 EER26712.1 - 9.9e-139 462.8 0.0 1.1e-138 462.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TipAS PF07739.8 EER26712.1 - 0.031 14.5 0.4 0.084 13.1 0.0 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Histidinol_dh PF00815.15 EER26713.1 - 4.7e-179 595.3 4.8 6.6e-179 594.8 3.4 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 EER26713.1 - 1.9e-25 88.2 0.1 3.9e-25 87.2 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EER26713.1 - 4.6e-10 39.6 0.1 1.6e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Utp11 PF03998.8 EER26714.1 - 4e-20 72.6 15.6 4.6e-20 72.4 10.8 1.0 1 0 0 1 1 1 1 Utp11 protein Snf7 PF03357.16 EER26714.1 - 0.19 11.0 14.7 6.3 6.1 8.0 2.2 2 0 0 2 2 2 0 Snf7 PRKCSH-like PF12999.2 EER26714.1 - 0.27 10.8 3.2 0.43 10.1 2.3 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like CDC45 PF02724.9 EER26714.1 - 1.7 6.5 9.6 2.1 6.3 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Cmc1 PF08583.5 EER26715.1 - 7.3e-15 54.5 9.5 2.3e-14 52.9 6.6 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EER26715.1 - 0.0092 15.3 1.5 0.017 14.5 1.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) U79_P34 PF03064.11 EER26715.1 - 0.059 12.8 1.8 0.068 12.6 1.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CHCH PF06747.8 EER26715.1 - 0.15 12.0 0.5 0.41 10.6 0.4 1.7 1 1 0 1 1 1 0 CHCH domain TFIID-31kDa PF02291.10 EER26716.1 - 8.8e-29 99.9 0.0 8.2e-23 80.6 0.0 2.8 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit SDA1 PF05285.7 EER26717.1 - 2e-95 319.8 33.1 2e-95 319.8 22.9 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EER26717.1 - 2.2e-24 85.4 0.1 6e-24 84.0 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Ribosomal_S7 PF00177.16 EER26718.1 - 1.8e-40 137.9 1.4 2.1e-40 137.7 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Metallophos PF00149.23 EER26719.1 - 1.1e-07 31.4 1.1 1.9e-07 30.6 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AMP-binding PF00501.23 EER26720.1 - 2.6e-56 190.8 0.5 2.6e-21 75.4 0.0 4.7 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 EER26720.1 - 3.9e-10 40.3 0.1 9.9e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EER26720.1 - 0.0011 18.7 3.0 0.0028 17.4 1.5 2.0 2 0 0 2 2 2 1 Gas vesicle protein G HMGL-like PF00682.14 EER26721.1 - 5.3e-67 225.9 0.0 8.9e-67 225.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EER26721.1 - 8.3e-24 83.8 0.1 2.4e-23 82.3 0.0 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain PaREP1 PF05942.6 EER26721.1 - 0.16 11.8 0.0 29 4.5 0.0 2.5 2 0 0 2 2 2 0 Archaeal PaREP1/PaREP8 family DEAD PF00270.24 EER26722.1 - 5.1e-45 152.9 0.0 1.3e-44 151.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER26722.1 - 3.6e-25 87.6 0.0 1.6e-24 85.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EER26722.1 - 9.8e-05 20.9 0.2 0.0026 16.2 0.0 3.0 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) APH PF01636.18 EER26723.1 - 0.015 15.0 0.0 0.034 13.8 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family PapD_N PF00345.15 EER26724.1 - 0.013 15.3 0.0 0.064 13.0 0.0 2.2 2 0 0 2 2 2 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain Acetyltransf_1 PF00583.19 EER26724.1 - 0.14 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF4045 PF13254.1 EER26725.1 - 4.5e-136 454.4 30.6 4.5e-136 454.4 21.2 4.3 3 1 0 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EER26725.1 - 6e-09 35.4 0.6 0.062 12.9 0.1 3.7 3 0 0 3 3 3 3 Gelsolin repeat ALO PF04030.9 EER26726.1 - 4.1e-89 298.6 0.0 6e-89 298.0 0.0 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EER26726.1 - 2.9e-31 107.7 0.0 4.6e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Zn_clus PF00172.13 EER26727.1 - 3.3e-09 36.4 12.1 7.6e-09 35.3 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DNL PF05180.7 EER26727.1 - 0.92 9.2 0.0 0.92 9.2 0.0 2.8 3 0 0 3 3 3 0 DNL zinc finger adh_short PF00106.20 EER26728.1 - 3.5e-19 69.3 0.1 2.2e-18 66.7 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EER26728.1 - 1.3e-10 41.2 0.1 2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EER26728.1 - 0.079 12.7 0.1 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PLDc_N PF13396.1 EER26728.1 - 0.11 12.1 0.5 0.27 10.9 0.4 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal PAPS_reduct PF01507.14 EER26728.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Zn_clus PF00172.13 EER26729.1 - 2.5e-08 33.6 11.5 2.5e-08 33.6 8.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EER26729.1 - 7.2e-06 25.0 0.1 1.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sec63 PF02889.11 EER26730.1 - 1.2e-51 175.8 0.0 3.3e-50 171.0 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EER26730.1 - 6.1e-18 64.3 1.1 1.4e-17 63.1 0.8 1.7 1 0 0 1 1 1 1 DnaJ domain Pkinase_Tyr PF07714.12 EER26731.1 - 4.7e-05 22.6 0.1 0.00058 19.0 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EER26731.1 - 5.8e-05 22.3 0.0 0.00013 21.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EER26732.1 - 1.7e-32 111.5 2.3 7.8e-08 32.5 0.0 5.7 3 1 2 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EER26732.1 - 3.1e-27 93.0 11.8 4e-09 35.8 0.3 8.0 7 0 0 7 7 7 6 Ankyrin repeat Pkinase PF00069.20 EER26732.1 - 5e-27 94.6 0.0 7.5e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.1 EER26732.1 - 2.4e-24 84.7 11.4 5.4e-08 32.8 0.1 7.0 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EER26732.1 - 3.9e-22 78.2 11.0 6.9e-05 23.2 0.1 7.9 4 3 5 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER26732.1 - 6.4e-14 50.6 10.4 4.3e-05 23.3 0.1 8.0 8 0 0 8 8 8 2 Ankyrin repeat Pkinase_Tyr PF07714.12 EER26732.1 - 1.7e-13 50.2 0.0 3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 EER26732.1 - 6e-07 29.3 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Pox_ser-thr_kin PF05445.6 EER26732.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_M24 PF00557.19 EER26734.1 - 7e-57 192.3 0.0 9.6e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EER26734.1 - 5e-23 80.9 0.0 9.1e-23 80.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SPRY PF00622.23 EER26735.1 - 1e-18 67.6 0.1 1.6e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 SPRY domain DUF4117 PF13491.1 EER26735.1 - 0.04 13.3 0.5 0.064 12.7 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) PDEase_II PF02112.10 EER26736.1 - 1.4e-52 178.7 0.0 4.4e-45 154.0 0.0 2.6 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EER26736.1 - 1.1e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EER26736.1 - 0.029 14.0 1.1 0.06 12.9 0.2 1.8 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Amidase PF01425.16 EER26737.1 - 5e-81 272.8 0.4 7.3e-81 272.2 0.3 1.2 1 0 0 1 1 1 1 Amidase GWT1 PF06423.7 EER26738.1 - 6.8e-43 146.0 2.3 1.9e-42 144.6 1.6 1.8 1 0 0 1 1 1 1 GWT1 Acyl-CoA_dh_1 PF00441.19 EER26739.1 - 6.5e-40 136.6 7.2 1e-39 136.0 5.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EER26739.1 - 1.2e-29 103.1 1.6 2.9e-29 101.9 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EER26739.1 - 2.3e-17 62.2 0.0 4.4e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EER26739.1 - 1.3e-14 54.6 3.7 2.4e-14 53.7 2.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EER26739.1 - 0.078 12.3 0.0 0.37 10.1 0.0 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Senescence PF06911.7 EER26740.1 - 4.5e-47 160.0 3.8 6.1e-47 159.6 2.6 1.2 1 0 0 1 1 1 1 Senescence-associated protein Pkinase PF00069.20 EER26741.1 - 2.8e-63 213.4 0.0 5.5e-63 212.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26741.1 - 6.4e-35 120.4 0.0 6.9e-30 103.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EER26741.1 - 8.1e-06 25.0 0.0 0.0052 15.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EER26741.1 - 0.00049 19.9 0.3 0.0045 16.7 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EER26741.1 - 0.0044 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 RIO1 family DUF2404 PF10296.4 EER26742.1 - 0.00038 20.5 0.0 0.0039 17.2 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Bap31 PF05529.7 EER26743.1 - 8.4e-66 221.0 0.3 9.8e-66 220.8 0.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 EER26743.1 - 0.00059 19.5 0.6 0.00059 19.5 0.4 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EER26743.1 - 0.0027 17.1 2.6 0.0088 15.5 0.2 2.8 3 0 0 3 3 3 1 Septum formation initiator Phage_GP20 PF06810.6 EER26743.1 - 0.0086 15.5 1.6 0.012 15.0 1.1 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF4349 PF14257.1 EER26743.1 - 0.084 12.0 0.3 0.15 11.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Fmp27_WPPW PF10359.4 EER26743.1 - 0.099 11.0 0.3 0.12 10.7 0.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF4472 PF14739.1 EER26743.1 - 0.18 12.3 1.1 0.4 11.1 0.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) Dus PF01207.12 EER26745.1 - 7.6e-43 146.4 0.0 6.4e-30 104.0 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EER26745.1 - 0.039 13.6 0.3 0.039 13.6 0.2 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tyr-DNA_phospho PF06087.7 EER26745.1 - 0.15 10.6 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Kelch_4 PF13418.1 EER26746.1 - 1.9e-24 85.1 11.4 2.7e-07 30.2 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EER26746.1 - 1.2e-23 82.6 0.8 9.5e-06 25.4 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EER26746.1 - 1.1e-22 78.8 3.1 1.1e-05 24.9 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EER26746.1 - 4.4e-22 77.2 4.5 0.00012 22.1 0.0 4.8 2 1 2 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EER26746.1 - 1.1e-19 69.9 10.7 4e-08 33.2 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EER26746.1 - 9.5e-17 60.2 4.0 0.00058 19.3 0.1 4.5 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 EER26746.1 - 3.8e-11 42.9 0.0 7.3e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 EER26747.1 - 6.7e-23 79.6 17.7 2e-06 27.4 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EER26747.1 - 5.2e-05 23.0 0.5 0.0098 15.6 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A TFIIA PF03153.8 EER26748.1 - 1.6e-83 281.6 0.2 1.9e-83 281.4 0.1 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit UPF0184 PF03670.8 EER26748.1 - 3 8.0 5.9 2.1 8.5 0.9 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) PAT1 PF09770.4 EER26748.1 - 3.1 5.9 23.0 4.6 5.3 15.1 1.7 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 zf-C2H2_4 PF13894.1 EER26749.1 - 7.4e-06 25.9 8.2 0.024 14.9 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EER26749.1 - 0.00012 22.1 12.2 0.047 14.0 0.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EER26749.1 - 0.0011 19.0 2.0 0.08 13.1 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EER26749.1 - 0.01 16.1 0.4 0.01 16.1 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger double domain FlxA PF14282.1 EER26750.1 - 0.005 16.7 1.6 0.005 16.7 1.1 2.4 2 0 0 2 2 2 1 FlxA-like protein TPR_MLP1_2 PF07926.7 EER26750.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EER26750.1 - 0.013 15.0 0.3 0.013 15.0 0.2 1.6 2 0 0 2 2 2 0 IncA protein Mei5 PF10376.4 EER26750.1 - 1.5 8.2 14.4 3.6 7.0 10.0 1.8 1 1 0 1 1 1 0 Double-strand recombination repair protein CDC45 PF02724.9 EER26750.1 - 3.3 5.6 9.9 5.4 4.9 6.9 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.1 EER26750.1 - 8.8 5.1 8.0 0.53 9.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Sel1 PF08238.7 EER26751.1 - 2.6e-36 123.2 42.1 7.1e-05 23.3 0.5 12.7 12 0 0 12 12 12 9 Sel1 repeat DUF1771 PF08590.5 EER26751.1 - 0.00081 19.3 0.9 0.00081 19.3 0.7 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) VGCC_beta4Aa_N PF12052.3 EER26751.1 - 0.0054 16.5 0.9 0.021 14.6 0.6 2.0 1 0 0 1 1 1 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal TPR_16 PF13432.1 EER26751.1 - 0.02 15.5 0.3 0.02 15.5 0.2 6.6 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF4419 PF14388.1 EER26751.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) TPR_19 PF14559.1 EER26751.1 - 1.9 8.8 8.2 8.4 6.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Aldedh PF00171.17 EER26752.1 - 3.1e-142 474.1 0.0 3.6e-142 473.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EER26752.1 - 0.015 14.0 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) WD40 PF00400.27 EER26753.1 - 5.3e-19 67.3 2.7 9.1e-08 31.7 0.2 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat Methyltransf_23 PF13489.1 EER26754.1 - 2.7e-14 53.1 0.0 4.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER26754.1 - 9.1e-08 32.6 0.0 8.2e-07 29.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER26754.1 - 3.6e-06 26.6 0.0 1.6e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EER26754.1 - 3.9e-05 22.7 0.0 0.00067 18.7 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.7 EER26754.1 - 4.4e-05 23.8 0.0 0.0019 18.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER26754.1 - 8e-05 22.9 0.2 0.0011 19.2 0.0 2.7 4 0 0 4 4 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER26754.1 - 0.00011 22.6 0.0 0.0043 17.5 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EER26754.1 - 0.00056 19.3 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EER26754.1 - 0.00065 19.7 0.0 0.00089 19.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EER26754.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EER26754.1 - 0.0049 16.0 0.0 0.092 11.8 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EER26754.1 - 0.023 13.9 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase CMAS PF02353.15 EER26754.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EER26754.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EER26754.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) WD40 PF00400.27 EER26755.1 - 8.8e-14 50.7 8.1 1.1e-06 28.2 0.4 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 EER26755.1 - 0.0002 21.1 0.1 0.72 9.5 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Peptidase_C3 PF00548.15 EER26755.1 - 0.096 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) RNA_pol_Rpb1_1 PF04997.7 EER26756.1 - 5e-117 390.9 0.0 7.8e-117 390.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EER26756.1 - 5e-105 350.7 0.1 1e-104 349.7 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EER26756.1 - 3.2e-69 232.1 0.0 7.2e-69 230.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EER26756.1 - 1.1e-64 217.6 1.3 2.5e-64 216.5 0.9 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EER26756.1 - 2.3e-47 160.6 0.0 5.2e-47 159.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EER26756.1 - 1.5e-43 147.7 7.1 3.7e-43 146.4 4.9 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EER26756.1 - 2.4e-37 126.9 0.1 5.3e-37 125.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EER26756.1 - 2.4e-12 45.8 191.4 0.031 14.4 7.1 14.2 11 2 4 15 15 15 11 RNA polymerase Rpb1 C-terminal repeat LNS2 PF08235.8 EER26757.1 - 4.9e-71 237.3 0.0 7.8e-71 236.7 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EER26757.1 - 6.7e-41 138.4 0.0 1.5e-40 137.2 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EER26757.1 - 0.0042 16.4 0.0 0.063 12.6 0.0 2.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) AF1Q PF15017.1 EER26757.1 - 0.29 11.0 5.8 0.91 9.4 4.1 1.8 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator fn3 PF00041.16 EER26758.1 - 0.0001 22.3 0.0 0.00031 20.7 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Reo_sigmaC PF04582.7 EER26758.1 - 0.13 11.3 2.3 0.28 10.3 1.6 1.5 1 0 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 EER26758.1 - 0.28 10.3 38.6 4.6 6.3 10.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.6 EER26758.1 - 3.5 7.4 37.8 0.11 12.3 15.3 3.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Thg1C PF14413.1 EER26759.1 - 5.4e-55 184.2 0.7 7e-55 183.9 0.5 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EER26759.1 - 1.5e-13 50.5 0.0 2.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase RNR_inhib PF08591.5 EER26761.1 - 1.2e-14 55.0 1.9 2.1e-14 54.2 0.0 2.4 3 0 0 3 3 3 1 Ribonucleotide reductase inhibitor AA_permease PF00324.16 EER26762.1 - 1.8e-56 191.4 31.9 1.4e-54 185.2 18.6 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EER26762.1 - 1.2e-17 63.5 29.4 1.2e-17 63.5 20.4 1.4 2 0 0 2 2 2 1 Amino acid permease HSP70 PF00012.15 EER26763.1 - 6.5e-60 202.6 13.8 3.1e-57 193.8 0.1 3.4 3 1 1 4 4 4 2 Hsp70 protein FGGY_C PF02782.11 EER26763.1 - 0.024 14.2 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EER26763.1 - 0.034 13.9 0.6 9.7 6.0 0.1 3.2 2 0 0 2 2 2 0 Cell division protein FtsA APH PF01636.18 EER26764.1 - 0.00079 19.2 0.6 0.0016 18.2 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Tubulin_3 PF14881.1 EER26766.1 - 3e-84 280.9 0.0 6.2e-84 279.9 0.0 1.5 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 EER26766.1 - 2.3e-42 143.6 0.0 4.5e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EER26766.1 - 8.2e-09 35.5 0.0 0.00013 21.8 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain HR1 PF02185.11 EER26767.1 - 0.00042 20.0 16.6 0.15 11.8 0.0 4.1 3 1 1 4 4 4 3 Hr1 repeat DUF4533 PF15047.1 EER26767.1 - 0.1 12.0 0.7 0.19 11.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) DUF2347 PF09804.4 EER26768.1 - 1.4e-103 346.0 0.0 1.9e-103 345.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EER26768.1 - 2.4e-51 174.3 0.1 3.8e-51 173.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 EER26768.1 - 3.3e-05 22.5 0.1 0.91 7.9 0.0 3.7 3 1 1 4 4 4 2 Transport protein Avl9 SPA PF08616.5 EER26768.1 - 0.0014 18.3 0.0 0.0042 16.7 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis EBP PF05241.7 EER26769.1 - 1.5e-66 223.1 8.8 1.8e-66 222.8 6.1 1.0 1 0 0 1 1 1 1 Emopamil binding protein SNF2_N PF00176.18 EER26771.1 - 2.9e-69 233.1 0.0 4.3e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER26771.1 - 1.3e-11 44.1 0.0 3.1e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER26771.1 - 3.3e-05 23.7 0.0 0.00012 21.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EER26771.1 - 0.0017 17.2 0.4 0.0036 16.1 0.3 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_2 PF07724.9 EER26772.1 - 4.8e-46 156.7 0.0 7e-45 152.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EER26772.1 - 9.3e-27 93.8 0.1 2.7e-14 53.5 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EER26772.1 - 8.2e-24 83.3 0.6 8.2e-24 83.3 0.4 2.4 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 EER26772.1 - 1e-16 61.4 12.1 5.4e-06 26.5 0.0 6.3 3 2 3 7 7 7 2 AAA ATPase domain AAA_5 PF07728.9 EER26772.1 - 3.4e-16 59.2 0.0 6.4e-10 38.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EER26772.1 - 1.3e-14 54.4 0.3 2.1e-05 24.6 0.0 4.2 3 2 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 EER26772.1 - 8.6e-09 35.0 0.0 1.5e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.15 EER26772.1 - 3.5e-08 33.2 2.0 3.7e-05 23.5 0.0 3.8 3 0 0 3 3 3 1 Clp amino terminal domain IstB_IS21 PF01695.12 EER26772.1 - 1.5e-07 31.0 0.0 0.024 14.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EER26772.1 - 2e-07 30.6 0.1 0.019 14.7 0.1 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA_17 PF13207.1 EER26772.1 - 2.5e-07 31.5 11.3 0.0046 17.7 0.0 4.5 4 2 0 4 4 2 2 AAA domain AAA_18 PF13238.1 EER26772.1 - 4.8e-07 30.1 4.3 0.0094 16.2 0.0 4.3 5 0 0 5 5 4 2 AAA domain Arch_ATPase PF01637.13 EER26772.1 - 2.1e-06 27.6 4.3 0.011 15.4 0.1 4.6 4 1 0 4 4 3 1 Archaeal ATPase Mg_chelatase PF01078.16 EER26772.1 - 8.3e-06 25.1 0.1 0.12 11.5 0.0 3.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EER26772.1 - 2e-05 23.6 0.0 0.00081 18.3 0.0 2.5 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 EER26772.1 - 5.5e-05 23.0 0.0 0.18 11.7 0.0 3.3 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EER26772.1 - 6.6e-05 22.6 0.0 0.39 10.4 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EER26772.1 - 6.6e-05 23.0 0.0 0.46 10.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 EER26772.1 - 9.1e-05 22.7 1.2 0.83 9.9 0.0 3.6 3 0 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 EER26772.1 - 0.00012 22.0 3.5 0.27 11.1 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_10 PF12846.2 EER26772.1 - 0.00024 20.6 3.7 1.3 8.3 0.0 5.1 4 2 0 6 6 5 1 AAA-like domain AAA_3 PF07726.6 EER26772.1 - 0.00028 20.5 0.0 1.1 8.8 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EER26772.1 - 0.00032 20.1 0.0 0.3 10.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.10 EER26772.1 - 0.00039 20.3 0.9 0.2 11.4 0.0 3.9 3 2 2 5 5 3 1 Type III restriction enzyme, res subunit DUF258 PF03193.11 EER26772.1 - 0.00077 18.6 0.0 0.38 9.9 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EER26772.1 - 0.0021 17.4 4.6 1.9 7.8 0.0 4.3 4 1 0 5 5 4 2 AAA domain NACHT PF05729.7 EER26772.1 - 0.0036 16.9 0.0 0.36 10.4 0.0 2.7 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 EER26772.1 - 0.0037 16.9 0.0 0.15 11.7 0.0 2.9 3 0 0 3 3 2 1 NTPase AAA_24 PF13479.1 EER26772.1 - 0.0039 16.7 0.0 2.6 7.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Torsin PF06309.6 EER26772.1 - 0.004 17.0 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 Torsin AAA_21 PF13304.1 EER26772.1 - 0.013 15.4 0.1 2.3 8.1 0.0 2.9 4 0 0 4 4 2 0 AAA domain SRP54 PF00448.17 EER26772.1 - 0.017 14.5 0.1 5.9 6.2 0.0 3.2 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain IncA PF04156.9 EER26772.1 - 0.045 13.3 6.3 0.14 11.6 4.3 1.8 1 0 0 1 1 1 0 IncA protein UPF0079 PF02367.12 EER26772.1 - 0.048 13.3 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 EER26772.1 - 0.11 12.4 0.0 2.1 8.3 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase PEPCK_ATP PF01293.15 EER26772.1 - 0.21 10.0 0.0 2.4 6.5 0.0 2.4 3 0 0 3 3 3 0 Phosphoenolpyruvate carboxykinase AAA_23 PF13476.1 EER26772.1 - 0.86 9.8 14.2 2.1 8.5 0.0 3.8 3 1 0 3 3 2 0 AAA domain Occludin_ELL PF07303.8 EER26772.1 - 1 10.1 7.9 1.5 9.5 3.7 2.6 2 0 0 2 2 1 0 Occludin homology domain Macoilin PF09726.4 EER26772.1 - 1.4 7.1 12.2 2.1 6.5 8.5 1.1 1 0 0 1 1 1 0 Transmembrane protein APG6 PF04111.7 EER26772.1 - 1.7 7.5 7.5 3.2 6.7 5.2 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EER26772.1 - 4.8 4.9 4.2 7.1 4.3 2.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sulfotransfer_3 PF13469.1 EER26773.1 - 0.11 13.3 0.0 0.23 12.3 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family Collagen PF01391.13 EER26773.1 - 0.53 9.8 7.2 2 8.0 0.3 2.4 2 0 0 2 2 2 0 Collagen triple helix repeat (20 copies) Prefoldin_2 PF01920.15 EER26774.1 - 1.8e-24 85.5 3.1 2.3e-24 85.2 2.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EER26774.1 - 0.0036 16.9 3.3 0.072 12.7 0.1 2.2 1 1 1 2 2 2 1 Prefoldin subunit FTA4 PF13093.1 EER26774.1 - 0.013 14.9 3.2 0.019 14.3 2.2 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 AAA_23 PF13476.1 EER26774.1 - 0.058 13.7 5.1 0.079 13.2 3.5 1.2 1 0 0 1 1 1 0 AAA domain Baculo_PEP_C PF04513.7 EER26774.1 - 0.083 12.7 0.9 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AATF-Che1 PF13339.1 EER26774.1 - 0.11 12.6 4.7 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor eIF-4B PF06273.6 EER26774.1 - 0.19 10.4 5.1 0.22 10.2 3.5 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Seryl_tRNA_N PF02403.17 EER26774.1 - 0.31 11.0 9.0 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 EER26774.1 - 0.34 11.1 2.5 8.2 6.7 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein PilJ PF13675.1 EER26774.1 - 0.36 11.1 5.5 6.7 7.0 3.8 2.1 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 EER26774.1 - 0.43 10.1 18.2 0.56 9.7 0.9 2.0 1 1 1 2 2 2 0 IncA protein DUF1664 PF07889.7 EER26774.1 - 0.46 10.2 2.7 2.8 7.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EER26774.1 - 0.74 9.6 14.6 0.45 10.3 0.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 EER26774.1 - 1 9.0 7.1 5.9 6.6 2.4 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TBPIP PF07106.8 EER26774.1 - 1.1 8.8 7.4 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EER26774.1 - 2.1 7.9 9.6 20 4.7 5.4 2.0 2 0 0 2 2 2 0 Mnd1 family ADIP PF11559.3 EER26774.1 - 4.1 7.2 12.4 21 4.9 6.1 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EER26774.1 - 4.5 6.2 12.8 19 4.1 6.7 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 EER26774.1 - 5.6 6.5 11.7 4.9 6.7 3.7 2.2 2 0 0 2 2 2 0 Septum formation initiator ATG27 PF09451.5 EER26775.1 - 2.5e-73 246.5 0.0 3.5e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EER26775.1 - 4.8e-07 29.6 0.0 3.5e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat DUF3140 PF11338.3 EER26775.1 - 0.45 10.6 2.6 1.1 9.4 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) Fungal_trans PF04082.13 EER26776.1 - 2.6e-25 88.8 0.3 4.3e-25 88.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26776.1 - 5.8e-06 26.1 12.8 1.3e-05 25.0 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.7 EER26778.1 - 2.7e-91 305.3 0.0 3.2e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EER26778.1 - 4.6e-07 29.7 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER26778.1 - 0.13 12.8 0.0 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain HSP70 PF00012.15 EER26779.1 - 2.7e-10 38.8 0.2 3.9e-09 34.9 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EER26779.1 - 0.006 16.2 0.2 0.013 15.1 0.2 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EER26779.1 - 0.12 10.9 0.0 0.41 9.1 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Chorismate_bind PF00425.13 EER26780.1 - 8.1e-84 280.9 0.0 1.1e-83 280.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EER26780.1 - 9.7e-38 129.5 0.0 1.5e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EER26780.1 - 2.6e-10 40.4 0.0 7e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EER26780.1 - 0.00013 21.4 0.8 0.00092 18.7 0.5 2.1 1 1 0 1 1 1 1 Peptidase C26 PsiA PF06952.6 EER26780.1 - 0.012 14.7 0.1 0.022 13.8 0.1 1.3 1 0 0 1 1 1 0 PsiA protein DUF3445 PF11927.3 EER26781.1 - 8.2e-59 198.9 0.1 1e-58 198.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) 4HBT_3 PF13622.1 EER26782.1 - 4e-48 164.3 0.5 5.9e-48 163.8 0.4 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EER26782.1 - 7.6e-23 80.5 0.0 2.2e-11 43.5 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase PAP_central PF04928.12 EER26783.1 - 8.9e-104 345.7 0.0 1.2e-103 345.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EER26783.1 - 3.9e-49 166.1 0.0 6.8e-49 165.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EER26783.1 - 3e-09 37.0 0.1 7.6e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_1 PF00561.15 EER26784.1 - 2.1e-15 56.9 0.0 4.5e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EER26784.1 - 2.3e-12 47.3 0.0 4.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER26784.1 - 0.0074 16.0 0.1 0.23 11.2 0.1 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EER26784.1 - 0.053 12.9 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Fungal_trans PF04082.13 EER26785.1 - 3.6e-19 68.6 0.0 3.2e-18 65.5 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26785.1 - 2e-07 30.8 7.9 3.5e-07 30.0 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1647 PF07801.6 EER26785.1 - 0.025 14.0 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) But2 PF09792.4 EER26787.1 - 0.0038 16.9 0.0 0.0094 15.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Mito_carr PF00153.22 EER26788.1 - 3.5e-46 154.8 6.4 1.3e-17 63.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 EER26788.1 - 0.056 13.0 1.8 0.074 12.6 0.4 1.9 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif UBA_4 PF14555.1 EER26789.1 - 1.8e-11 43.3 0.0 4.8e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EER26789.1 - 3.1e-09 36.7 0.0 7.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 UBX domain DDRGK PF09756.4 EER26789.1 - 2.7 7.3 15.1 4.5 6.6 10.5 1.2 1 0 0 1 1 1 0 DDRGK domain PALP PF00291.20 EER26790.1 - 1.5e-48 165.6 0.0 1.9e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LSM PF01423.17 EER26791.1 - 6.2e-19 67.3 0.2 8.4e-19 66.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF533 PF04391.7 EER26791.1 - 0.13 11.5 1.6 0.19 11.1 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Zn_clus PF00172.13 EER26792.1 - 0.018 14.9 8.8 0.033 14.0 6.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 EER26793.1 - 3e-53 179.8 0.0 4.3e-53 179.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EER26793.1 - 1.2e-17 63.6 0.0 2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EER26793.1 - 0.0013 18.7 0.0 0.0042 17.1 0.0 1.9 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Big_1 PF02369.11 EER26793.1 - 0.0046 16.8 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) DUF290 PF01060.18 EER26793.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Transthyretin-like family Vps39_2 PF10367.4 EER26794.1 - 9.9e-06 25.6 0.0 3.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EER26794.1 - 0.039 13.9 0.2 3.9 7.5 0.0 3.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 EER26794.1 - 0.11 12.1 0.0 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS STIL_N PF15253.1 EER26794.1 - 0.21 10.2 3.9 0.37 9.4 2.7 1.3 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus CASP_C PF08172.7 EER26795.1 - 1.7e-87 292.5 2.3 1.7e-87 292.5 1.6 3.3 2 1 0 2 2 2 1 CASP C terminal DUF904 PF06005.7 EER26795.1 - 0.11 12.7 0.3 0.11 12.7 0.2 6.5 4 3 0 4 4 4 0 Protein of unknown function (DUF904) Ribosomal_L22 PF00237.14 EER26796.1 - 3.9e-35 119.9 0.1 5.7e-35 119.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1609 PF07753.6 EER26796.1 - 0.067 12.5 0.1 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1609) DUF4506 PF14958.1 EER26796.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) 2-Hacid_dh_C PF02826.14 EER26797.1 - 5.5e-55 185.2 0.0 7e-55 184.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER26797.1 - 4.9e-17 61.6 0.0 5.5e-17 61.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EER26797.1 - 0.097 12.5 0.0 0.22 11.3 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.7 EER26798.1 - 6.1e-26 90.3 0.1 9.8e-26 89.6 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER26798.1 - 8.1e-12 44.8 0.0 2.3e-11 43.3 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EER26798.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase ADH_zinc_N_2 PF13602.1 EER26798.1 - 0.034 15.0 0.0 0.072 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pyr_redox PF00070.22 EER26798.1 - 0.041 14.2 0.9 11 6.4 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EER26798.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EER26798.1 - 0.074 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF281 PF03436.8 EER26798.1 - 0.087 12.8 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF281) adh_short PF00106.20 EER26799.1 - 1.6e-30 106.2 0.6 2e-30 105.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER26799.1 - 4.6e-18 65.8 0.1 5.7e-18 65.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER26799.1 - 7.3e-11 42.0 0.2 1.1e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EER26799.1 - 6.3e-08 32.3 0.1 8.7e-08 31.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EER26799.1 - 0.0018 18.2 2.2 0.058 13.3 1.6 2.8 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EER26799.1 - 0.025 14.3 1.9 0.025 14.3 1.3 1.9 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ACT_7 PF13840.1 EER26799.1 - 0.13 11.7 0.5 0.41 10.2 0.1 2.0 2 0 0 2 2 2 0 ACT domain Fungal_trans PF04082.13 EER26800.1 - 5.1e-11 41.9 0.0 1.5e-10 40.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26800.1 - 8.5e-05 22.3 7.2 0.0046 16.8 0.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain SSP160 PF06933.6 EER26800.1 - 7.4 4.4 21.2 13 3.6 14.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 adh_short PF00106.20 EER26801.1 - 1.5e-34 119.3 2.2 2.3e-34 118.7 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER26801.1 - 2.4e-23 83.1 0.1 3.2e-23 82.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER26801.1 - 9.8e-15 54.6 2.4 2.3e-14 53.4 1.5 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EER26801.1 - 6.1e-08 32.3 0.1 8.2e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EER26801.1 - 0.00077 19.2 0.2 0.0016 18.2 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PfkB PF00294.19 EER26801.1 - 0.0018 17.4 0.3 0.4 9.7 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase NAD_binding_10 PF13460.1 EER26801.1 - 0.0027 17.7 2.5 0.0091 16.0 0.9 2.3 2 2 0 2 2 2 1 NADH(P)-binding Glyco_trans_4_4 PF13579.1 EER26801.1 - 0.0033 17.5 0.2 3.3 7.8 0.0 2.3 2 1 0 2 2 2 2 Glycosyl transferase 4-like domain Polysacc_synt_2 PF02719.10 EER26801.1 - 0.0079 15.1 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Glyco_transf_5 PF08323.6 EER26801.1 - 0.0094 15.4 0.0 0.051 13.0 0.0 2.0 2 0 0 2 2 2 1 Starch synthase catalytic domain ADH_zinc_N PF00107.21 EER26801.1 - 0.015 14.8 0.3 0.033 13.7 0.2 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 EER26801.1 - 0.016 14.0 1.2 0.042 12.7 0.4 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 EER26801.1 - 0.016 15.0 0.1 0.034 13.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EER26801.1 - 0.023 14.9 0.2 0.2 11.9 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 EER26801.1 - 0.024 13.6 1.5 0.028 13.5 0.4 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 EER26801.1 - 0.026 13.7 0.9 0.043 13.0 0.6 1.3 1 0 0 1 1 1 0 NmrA-like family ApbA PF02558.11 EER26801.1 - 0.032 13.6 0.2 0.09 12.2 0.1 1.7 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EER26801.1 - 0.035 14.1 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EER26801.1 - 0.038 13.1 0.1 0.068 12.3 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 EER26801.1 - 0.042 12.4 0.0 0.061 11.9 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase F420_oxidored PF03807.12 EER26801.1 - 0.052 13.9 0.2 0.12 12.8 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent CW_binding_2 PF04122.7 EER26801.1 - 0.065 13.4 0.4 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Putative cell wall binding repeat 2 3HCDH_N PF02737.13 EER26801.1 - 0.12 11.9 0.7 0.42 10.2 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ETF PF01012.16 EER26801.1 - 0.23 11.1 3.4 1 9.0 0.5 2.7 2 1 0 2 2 2 0 Electron transfer flavoprotein domain Ferric_reduct PF01794.14 EER26802.1 - 4.1e-21 75.3 6.4 9.3e-21 74.2 4.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EER26802.1 - 3.8e-14 52.8 0.1 3.7e-11 43.1 0.1 3.0 2 1 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EER26802.1 - 3e-12 46.3 0.0 7.4e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EER26802.1 - 0.0047 17.4 0.0 0.018 15.5 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Herpes_UL20 PF04544.7 EER26802.1 - 0.049 13.4 0.1 0.096 12.4 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 GAT PF03127.9 EER26803.1 - 3.2e-14 52.7 0.3 7.9e-14 51.4 0.2 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EER26803.1 - 0.00054 19.6 0.4 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 VHS domain F-box-like PF12937.2 EER26804.1 - 0.003 17.2 2.2 0.76 9.5 0.0 3.0 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 EER26804.1 - 0.0061 16.1 1.5 0.094 12.3 0.0 2.8 2 0 0 2 2 2 1 F-box domain KcnmB2_inactiv PF09303.5 EER26804.1 - 0.1 12.4 1.1 0.25 11.1 0.7 1.6 1 0 0 1 1 1 0 KCNMB2, ball and chain domain RRN7 PF11781.3 EER26804.1 - 0.23 10.9 2.9 0.57 9.7 2.0 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Cation_efflux PF01545.16 EER26805.1 - 8.7e-27 93.9 3.6 1e-26 93.6 2.5 1.1 1 0 0 1 1 1 1 Cation efflux family Oxidored_q2 PF00420.19 EER26805.1 - 3.4 7.3 6.7 0.26 10.9 0.6 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 2_5_RNA_ligase2 PF13563.1 EER26806.1 - 2.1e-27 95.6 0.0 5.3e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EER26806.1 - 2.6e-23 82.1 0.0 5.4e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 EER26806.1 - 7.9e-14 52.1 0.0 1.4e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 EER26806.1 - 2.1e-13 50.1 0.7 7.9e-13 48.3 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF504) PAP_RNA-bind PF04926.10 EER26806.1 - 6.8e-08 32.1 0.1 1.4e-07 31.2 0.1 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EER26806.1 - 0.0043 17.3 0.1 0.077 13.3 0.1 2.6 1 1 1 2 2 2 1 Nucleotidyltransferase domain DUF4115 PF13464.1 EER26807.1 - 0.11 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4115) SOG2 PF10428.4 EER26808.1 - 2.1 6.9 8.5 3.6 6.1 5.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Aminotran_1_2 PF00155.16 EER26809.1 - 6e-22 78.0 0.0 7.6e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EER26809.1 - 0.0014 17.2 0.0 0.034 12.7 0.0 2.0 2 0 0 2 2 2 2 Alanine-glyoxylate amino-transferase Pectate_lyase_3 PF12708.2 EER26810.1 - 6.3e-90 301.2 19.4 2e-72 243.9 7.9 2.9 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EER26810.1 - 2.9e-07 29.8 1.0 0.005 16.2 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DUF605 PF04652.11 EER26810.1 - 0.78 9.0 16.5 0.71 9.2 10.2 1.7 2 0 0 2 2 2 0 Vta1 like SOG2 PF10428.4 EER26810.1 - 3.7 6.1 5.9 5.4 5.5 4.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans_2 PF11951.3 EER26811.1 - 5.8e-14 51.4 0.1 2.6e-08 32.8 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26811.1 - 1.3e-09 37.7 8.6 3e-09 36.6 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EER26813.1 - 1.2e-61 208.3 0.0 1.6e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER26813.1 - 3.1e-07 31.2 0.2 8e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ATP-grasp_4 PF13535.1 EER26814.1 - 1.3e-25 90.2 0.3 1.9e-23 83.1 0.1 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EER26814.1 - 1.1e-05 24.3 0.0 0.038 12.7 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EER26814.1 - 0.00015 21.2 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EER26814.1 - 0.0032 17.3 0.1 0.071 12.9 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain RimK PF08443.6 EER26814.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 RimK-like ATP-grasp domain GSH-S_ATP PF02955.11 EER26814.1 - 0.037 13.1 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain TTL PF03133.10 EER26814.1 - 0.25 10.2 0.0 1.6 7.6 0.0 1.9 2 0 0 2 2 2 0 Tubulin-tyrosine ligase family AMP-binding PF00501.23 EER26815.1 - 1.9e-80 270.3 0.0 2.9e-80 269.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EER26815.1 - 1.1e-09 37.5 0.0 2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 EER26815.1 - 6.8e-08 33.3 0.1 1.7e-07 32.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EER26815.1 - 1e-07 32.0 0.1 2.8e-06 27.4 0.0 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Cys_Met_Meta_PP PF01053.15 EER26816.1 - 2.9e-32 111.3 0.0 3.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EER26816.1 - 1.1e-05 24.6 0.0 1.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II FMN_dh PF01070.13 EER26817.1 - 8.4e-110 366.9 0.0 1.1e-109 366.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EER26817.1 - 1.3e-06 27.6 0.0 2.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EER26817.1 - 1.8e-06 27.1 0.2 3.8e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EER26817.1 - 0.01 15.1 0.1 0.21 10.8 0.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.9 EER26817.1 - 0.078 12.0 0.9 11 5.0 0.0 2.9 2 1 1 3 3 3 0 Thiazole biosynthesis protein ThiG FMO-like PF00743.14 EER26818.1 - 6.3e-48 163.2 0.0 2.9e-43 147.8 0.0 2.7 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EER26818.1 - 5.7e-26 91.8 0.0 8.2e-25 88.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER26818.1 - 4.6e-09 36.4 0.0 1.6e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER26818.1 - 4e-08 33.1 1.1 4.1e-07 29.9 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EER26818.1 - 5.1e-08 32.2 1.2 0.0019 17.1 0.1 4.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EER26818.1 - 1e-07 31.1 0.6 2.6e-07 29.8 0.0 1.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EER26818.1 - 2.7e-07 30.4 3.7 8.8e-07 28.8 0.5 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EER26818.1 - 7.4e-07 29.3 0.8 0.013 15.5 0.1 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EER26818.1 - 7.4e-05 22.5 2.5 0.024 14.4 0.4 2.6 2 0 0 2 2 2 2 ThiF family NAD_binding_10 PF13460.1 EER26818.1 - 0.00013 22.0 1.3 0.011 15.7 0.0 3.1 3 0 0 3 3 3 1 NADH(P)-binding NAD_binding_7 PF13241.1 EER26818.1 - 0.00014 22.0 0.2 0.025 14.8 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_2 PF03446.10 EER26818.1 - 0.00061 19.6 0.1 0.092 12.5 0.0 2.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 EER26818.1 - 0.00082 19.7 3.7 0.17 12.3 0.3 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER26818.1 - 0.0011 18.1 0.0 0.0059 15.7 0.0 2.0 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 EER26818.1 - 0.0014 17.7 0.2 1.1 8.3 0.0 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EER26818.1 - 0.0072 15.4 0.2 0.31 10.0 0.1 2.3 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.20 EER26818.1 - 0.0083 16.0 0.7 0.8 9.6 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase IlvN PF07991.7 EER26818.1 - 0.023 14.0 0.1 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EER26818.1 - 0.071 12.7 0.7 1.7 8.2 0.2 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EER26818.1 - 0.083 11.9 1.1 0.71 8.8 0.0 2.4 2 1 1 3 3 3 0 Flavin containing amine oxidoreductase ApbA PF02558.11 EER26818.1 - 0.12 11.8 0.6 1.5 8.2 0.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EER26818.1 - 0.17 11.2 0.5 0.59 9.4 0.1 2.1 3 0 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MFS_1 PF07690.11 EER26819.1 - 1.3e-45 155.7 57.9 2.6e-43 148.0 38.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER26819.1 - 1.9e-13 49.5 33.7 4.3e-13 48.3 23.4 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EER26819.1 - 5.8e-08 31.5 1.1 5.8e-08 31.5 0.8 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein DUF1180 PF06679.7 EER26819.1 - 0.028 14.2 0.1 0.087 12.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) p450 PF00067.17 EER26820.1 - 1.2e-30 106.4 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EER26821.1 - 5.4e-71 239.0 0.8 9.6e-71 238.2 0.6 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EER26821.1 - 7.2e-34 116.1 0.0 1.6e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EER26821.1 - 1.3e-25 90.4 0.0 2.3e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EER26821.1 - 1.7e-19 70.0 0.0 6.2e-19 68.2 0.0 2.0 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_3 PF07859.8 EER26821.1 - 3.5e-14 52.8 0.0 2.2e-12 47.0 0.0 2.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold PP-binding PF00550.20 EER26821.1 - 1.4e-11 44.4 0.8 2.9e-11 43.4 0.5 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EER26821.1 - 1.5e-11 44.2 0.0 4.7e-09 36.1 0.0 2.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER26821.1 - 1.6e-09 37.2 0.2 6.2e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EER26821.1 - 4.9e-09 36.4 0.7 9.2e-07 28.9 0.1 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EER26821.1 - 6.2e-05 22.3 0.1 0.00043 19.6 0.0 2.4 3 0 0 3 3 3 1 Dienelactone hydrolase family Thiolase_N PF00108.18 EER26821.1 - 0.00076 18.5 0.2 0.0015 17.6 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_2 PF02230.11 EER26821.1 - 0.018 14.4 0.0 0.072 12.5 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EER26821.1 - 0.061 12.7 0.0 4.6 6.5 0.0 2.5 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.23 EER26821.1 - 0.36 9.4 0.0 0.6 8.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Beta_elim_lyase PF01212.16 EER26822.1 - 5.2e-66 222.7 0.0 6.7e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EER26822.1 - 0.025 13.6 0.2 0.57 9.1 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family HTH_Tnp_ISL3 PF13542.1 EER26822.1 - 0.057 12.6 0.0 0.58 9.3 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Pkinase PF00069.20 EER26823.1 - 4e-16 58.9 0.0 4.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EER26824.1 - 5.7e-32 109.9 0.6 2.5e-19 69.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EER26824.1 - 2.7e-23 81.4 3.1 5.3e-09 36.0 0.1 3.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EER26824.1 - 2.4e-20 71.2 3.4 2e-06 27.3 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EER26824.1 - 2.1e-19 69.4 4.4 3.8e-09 36.8 0.1 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER26824.1 - 1.1e-15 56.2 0.8 0.002 18.2 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat bZIP_1 PF00170.16 EER26824.1 - 0.0039 17.1 10.0 0.0092 15.9 6.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor KCNQC3-Ank-G_bd PF11956.3 EER26824.1 - 0.053 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin-G binding motif of KCNQ2-3 bZIP_Maf PF03131.12 EER26824.1 - 7.4 6.9 17.3 0.19 12.0 6.4 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor APH PF01636.18 EER26825.1 - 5.2e-11 42.7 0.0 8.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pyr_redox_2 PF07992.9 EER26826.1 - 1.5e-24 86.9 0.0 2.3e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER26826.1 - 3.1e-10 40.3 0.0 1.9e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER26826.1 - 0.015 15.3 0.0 0.93 9.5 0.0 2.9 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER26826.1 - 0.029 14.1 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Amidase PF01425.16 EER26827.1 - 3.5e-86 289.7 0.0 4.2e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 Amidase TMEM117 PF15113.1 EER26827.1 - 0.22 10.0 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 TMEM117 protein family adh_short PF00106.20 EER26828.1 - 1.6e-27 96.4 0.8 2.5e-27 95.8 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER26828.1 - 1.9e-23 83.5 0.2 2.4e-23 83.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER26828.1 - 4.2e-12 46.0 0.3 6.9e-12 45.3 0.2 1.3 1 0 0 1 1 1 1 KR domain DUF3391 PF11871.3 EER26828.1 - 0.087 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3431 PF11913.3 EER26829.1 - 1.3e-69 234.0 0.0 1.5e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Aldolase_II PF00596.16 EER26830.1 - 1.5e-46 158.3 0.2 1.9e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HTH_29 PF13551.1 EER26831.1 - 0.017 15.2 0.1 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn helix MFS_1 PF07690.11 EER26832.1 - 3e-26 91.9 40.2 2.1e-19 69.4 5.9 2.8 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EER26832.1 - 3.4e-08 32.5 0.6 3.4e-08 32.5 0.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter AA_permease_2 PF13520.1 EER26834.1 - 3.5e-57 193.8 48.0 4.5e-57 193.4 33.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER26834.1 - 8e-23 80.5 39.1 1.2e-22 79.8 27.1 1.2 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 EER26834.1 - 0.082 12.7 0.0 0.082 12.7 0.0 3.6 4 0 0 4 4 4 0 Gram positive anchor ADH_zinc_N PF00107.21 EER26835.1 - 3.1e-17 62.3 0.0 5.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER26835.1 - 3e-10 41.0 0.0 6.8e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER26835.1 - 2.3e-09 36.9 0.1 2.2e-06 27.3 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 EER26836.1 - 9.2e-39 133.1 33.9 9.2e-39 133.1 23.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER26836.1 - 1.3e-11 43.8 25.0 1.4e-10 40.4 17.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EER26836.1 - 2e-06 26.3 2.7 2e-06 26.3 1.9 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Vps55 PF04133.9 EER26836.1 - 0.0086 15.8 1.6 0.0086 15.8 1.1 2.9 2 1 0 2 2 2 1 Vacuolar protein sorting 55 DUF4231 PF14015.1 EER26836.1 - 0.13 12.2 5.7 19 5.3 1.1 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF4231) p53-inducible11 PF14936.1 EER26836.1 - 0.24 11.3 1.6 1.4 8.8 0.2 2.3 2 0 0 2 2 2 0 Tumour protein p53-inducible protein 11 Alpha-amylase PF00128.19 EER26837.1 - 9.9e-33 113.8 0.2 3.1e-32 112.2 0.1 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EER26837.1 - 9.8e-09 33.5 0.1 0.021 12.6 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF3242 PF11586.3 EER26837.1 - 0.016 14.7 1.9 0.035 13.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3242) Pkinase PF00069.20 EER26838.1 - 3.2e-08 33.0 0.0 5.3e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER26838.1 - 0.15 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3455 PF11937.3 EER26839.1 - 3.9e-38 131.1 0.0 4.6e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Fibrillarin PF01269.12 EER26840.1 - 1.6e-107 357.6 0.0 1.9e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EER26840.1 - 1.6e-06 27.8 0.0 2.6e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EER26840.1 - 0.027 14.0 0.1 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Epimerase PF01370.16 EER26841.1 - 4.1e-20 72.2 0.0 5.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EER26841.1 - 6.2e-13 48.0 0.0 8e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EER26841.1 - 5.5e-07 29.6 0.4 9.7e-07 28.8 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EER26841.1 - 7.3e-07 28.3 0.4 1.9e-05 23.6 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EER26841.1 - 2.2e-05 23.5 0.0 3.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.18 EER26841.1 - 0.00066 19.5 0.1 0.0034 17.1 0.0 2.0 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EER26841.1 - 0.00088 19.3 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EER26841.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EER26841.1 - 0.0048 15.8 0.0 0.037 12.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EER26841.1 - 0.02 13.8 0.1 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NmrA PF05368.8 EER26841.1 - 0.089 12.0 0.1 0.4 9.9 0.1 1.9 2 0 0 2 2 2 0 NmrA-like family Peptidase_M16 PF00675.15 EER26842.1 - 5.7e-57 191.6 0.3 1.9e-56 189.9 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EER26842.1 - 9.3e-40 136.2 0.0 1.4e-38 132.3 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain MFS_1 PF07690.11 EER26843.1 - 6e-29 100.8 55.1 3e-26 91.9 33.5 3.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Dispanin PF04505.7 EER26843.1 - 8.2 6.0 10.7 0.28 10.7 1.5 2.9 3 0 0 3 3 3 0 Interferon-induced transmembrane protein ADH_zinc_N PF00107.21 EER26844.1 - 1.2e-20 73.3 0.0 1.8e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER26844.1 - 3.9e-10 40.7 0.0 7.7e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CybS PF05328.7 EER26845.1 - 7.3e-51 171.2 0.0 9.5e-51 170.9 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EER26845.1 - 0.058 13.2 0.5 0.65 9.8 0.0 2.0 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Maf PF02545.9 EER26846.1 - 1.3e-44 151.6 0.0 1.7e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.21 EER26847.1 - 4.8e-09 35.7 0.0 1.1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.7 EER26847.1 - 0.015 14.4 1.0 0.025 13.7 0.5 1.5 1 1 0 1 1 1 0 Umbravirus long distance movement (LDM) family GFA PF04828.9 EER26848.1 - 0.00048 20.0 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ribonuc_L-PSP PF01042.16 EER26851.1 - 1.2e-34 118.6 0.0 1.4e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Zn_clus PF00172.13 EER26853.1 - 4.4e-08 32.9 9.1 7.2e-08 32.2 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA PF00092.23 EER26854.1 - 7e-07 29.1 0.0 9e-06 25.5 0.0 2.4 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 EER26854.1 - 3.3e-06 27.3 0.0 8.2e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain Apc4 PF12896.2 EER26856.1 - 9.8e-65 217.7 0.4 1.4e-64 217.2 0.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EER26856.1 - 1.9e-17 62.4 0.0 2.4e-16 58.9 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EER26856.1 - 0.0066 16.2 0.0 0.28 11.1 0.0 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat HEAT_2 PF13646.1 EER26857.1 - 1.5e-15 57.2 4.3 7.5e-05 22.9 0.0 6.3 3 1 4 7 7 7 5 HEAT repeats HEAT PF02985.17 EER26857.1 - 9e-14 50.2 10.3 0.00012 21.8 0.0 8.7 10 1 1 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 EER26857.1 - 8.7e-13 48.3 8.0 4.7e-07 30.1 0.0 7.7 7 2 3 10 10 10 2 HEAT-like repeat IBN_N PF03810.14 EER26857.1 - 8.9e-08 31.9 0.2 1.6e-06 27.9 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EER26857.1 - 1.8e-07 30.7 1.1 0.084 12.2 0.0 4.7 3 2 1 5 5 5 2 CLASP N terminal Arm PF00514.18 EER26857.1 - 4.8e-07 29.3 1.0 0.7 9.8 0.1 5.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat MMS19_N PF14500.1 EER26857.1 - 0.0022 17.2 0.5 0.69 9.1 0.2 2.6 2 0 0 2 2 2 2 Dos2-interacting transcription regulator of RNA-Pol-II Xpo1 PF08389.7 EER26857.1 - 0.0031 17.4 0.8 2.6 7.9 0.0 4.6 4 1 1 5 5 5 1 Exportin 1-like protein HEAT_PBS PF03130.11 EER26857.1 - 0.0075 16.6 0.0 15 6.3 0.0 4.6 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Ribosomal_S8 PF00410.14 EER26858.1 - 5.8e-25 87.6 0.1 8.1e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 DUF1995 PF09353.5 EER26858.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1995) Fra10Ac1 PF09725.4 EER26859.1 - 0.012 15.6 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Folate-sensitive fragile site protein Fra10Ac1 ubiquitin PF00240.18 EER26860.1 - 2.7e-07 29.8 0.0 5.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EER26860.1 - 0.0023 18.0 0.0 0.0057 16.8 0.0 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EER26860.1 - 0.0039 16.8 0.0 0.0087 15.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PS_Dcarbxylase PF02666.10 EER26861.1 - 6.6e-82 273.7 0.0 1.5e-81 272.5 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase E1-E2_ATPase PF00122.15 EER26862.1 - 1.8e-66 223.4 2.3 3.5e-66 222.5 1.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EER26862.1 - 7.1e-35 120.1 8.7 7.1e-35 120.1 6.0 2.9 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EER26862.1 - 2.5e-29 103.2 0.0 4.3e-28 99.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EER26862.1 - 6.9e-18 63.8 0.0 1.6e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EER26862.1 - 1.9e-16 59.7 0.0 4.2e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EER26862.1 - 3.2e-13 50.2 0.0 8.2e-13 48.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER26862.1 - 6.6e-07 29.1 0.3 0.0005 19.7 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2463 PF09591.5 EER26862.1 - 0.027 14.0 0.9 0.058 12.9 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) APC10 PF03256.11 EER26863.1 - 5.5e-41 140.2 0.1 1.4e-40 138.9 0.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) FYDLN_acid PF09538.5 EER26863.1 - 3.6 8.2 18.6 3.4 8.3 5.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Iso_dh PF00180.15 EER26864.1 - 9.7e-132 439.1 0.0 1.1e-131 438.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Methyltransf_23 PF13489.1 EER26865.1 - 6.2e-20 71.5 0.0 8.9e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER26865.1 - 8.6e-09 35.1 0.0 1.7e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER26865.1 - 2.5e-08 34.4 0.0 4.4e-07 30.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER26865.1 - 2e-07 31.3 0.0 1.4e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER26865.1 - 3.1e-07 30.7 0.0 6.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER26865.1 - 0.00013 22.2 0.0 0.00048 20.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER26865.1 - 0.0055 16.0 0.0 0.046 13.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EER26865.1 - 0.0071 15.4 0.0 0.019 14.1 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EER26865.1 - 0.0096 15.9 0.0 0.15 12.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EER26865.1 - 0.028 13.8 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 EER26865.1 - 0.034 13.1 0.0 0.19 10.7 0.0 2.0 2 1 0 2 2 2 0 Putative methyltransferase FtsJ PF01728.14 EER26865.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase CDP-OH_P_transf PF01066.16 EER26866.1 - 4.8e-17 62.1 6.2 4.8e-17 62.1 4.3 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PP2C PF00481.16 EER26867.1 - 2.3e-33 115.6 0.0 1.9e-28 99.5 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EER26867.1 - 0.0022 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C AAA_13 PF13166.1 EER26868.1 - 0.85 7.9 3.3 2.1 6.6 0.8 2.0 2 0 0 2 2 2 0 AAA domain RRM_1 PF00076.17 EER26869.1 - 8e-41 137.5 0.5 1.3e-19 69.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER26869.1 - 3.3e-33 113.4 0.1 1.6e-18 66.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EER26869.1 - 1e-29 102.5 0.2 2.8e-29 101.2 0.2 1.8 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EER26869.1 - 4.6e-21 74.4 0.0 4.2e-09 36.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EER26869.1 - 0.018 14.8 0.0 0.072 12.9 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif Cyt-b5 PF00173.23 EER26870.1 - 3e-21 75.0 0.4 4.4e-20 71.2 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EER26870.1 - 3e-08 34.0 22.2 3.2e-08 33.9 12.7 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily OMPdecase PF00215.19 EER26871.1 - 2.3e-06 27.2 0.0 8.8e-05 22.0 0.0 2.3 2 0 0 2 2 2 2 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF1778 PF08681.6 EER26871.1 - 0.093 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) Cu-oxidase_2 PF07731.9 EER26872.1 - 2.5e-05 23.7 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Multicopper oxidase Adap_comp_sub PF00928.16 EER26873.1 - 1.9e-19 69.8 0.1 2.8e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EER26873.1 - 2.1e-07 30.7 0.1 3.5e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 EER26873.1 - 0.0047 17.0 0.3 0.0099 16.0 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF2420 PF10336.4 EER26874.1 - 1.2e-12 47.4 0.0 2.4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Amidohydro_2 PF04909.9 EER26875.1 - 4e-18 65.9 0.0 5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 EER26876.1 - 1.7e-23 82.8 0.2 2.7e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26876.1 - 1.9e-10 40.4 7.3 3.2e-10 39.7 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Packaging_FI PF14000.1 EER26876.1 - 0.072 13.2 0.3 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 DNA packaging protein FI Ran-binding PF05508.6 EER26876.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 RanGTP-binding protein Sugarporin_N PF11471.3 EER26876.1 - 0.24 11.0 0.1 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Opy2 PF09463.5 EER26876.1 - 8.3 6.5 9.1 1.1 9.4 2.5 2.2 1 1 1 2 2 2 0 Opy2 protein tRNA-synt_2b PF00587.20 EER26877.1 - 7.3e-50 168.9 0.0 1e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EER26877.1 - 1.7e-05 24.6 0.0 5.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain p450 PF00067.17 EER26878.1 - 5.8e-35 120.6 0.0 8.3e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ECH PF00378.15 EER26879.1 - 2.3e-35 121.8 0.0 4.3e-35 120.9 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pyr_redox_2 PF07992.9 EER26880.1 - 1.1e-37 129.8 0.2 1.6e-37 129.3 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EER26880.1 - 4.4e-32 110.3 0.1 8.2e-32 109.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EER26880.1 - 1.2e-13 51.2 0.1 1.2e-13 51.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER26880.1 - 3e-08 33.9 0.0 1.3e-06 28.6 0.0 2.7 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EER26880.1 - 0.00027 20.6 0.1 0.00027 20.6 0.0 2.1 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EER26880.1 - 0.0015 17.4 1.8 0.3 9.9 0.3 2.7 4 0 0 4 4 4 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EER26880.1 - 0.0059 15.6 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EER26880.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 EER26880.1 - 0.025 13.4 3.5 0.15 10.9 0.2 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase K_oxygenase PF13434.1 EER26880.1 - 0.028 13.3 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_Gly3P_dh_N PF01210.18 EER26880.1 - 0.037 13.7 0.0 0.037 13.7 0.0 1.8 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EER26880.1 - 0.038 13.3 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EER26880.1 - 0.2 10.0 2.1 2.6 6.4 0.2 2.8 3 1 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.19 EER26880.1 - 1.2 7.8 10.2 2.6 6.8 0.9 2.9 4 0 0 4 4 4 0 FAD binding domain Pkinase PF00069.20 EER26881.1 - 2.3e-49 167.9 0.0 1.2e-46 158.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER26881.1 - 7.1e-31 107.2 0.0 6.3e-30 104.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EER26881.1 - 0.0021 16.9 0.1 0.0034 16.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 EER26881.1 - 0.003 16.5 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 EER26881.1 - 0.031 13.0 0.0 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mem_trans PF03547.13 EER26882.1 - 1e-49 168.8 0.0 1.6e-49 168.2 0.0 1.3 1 1 0 1 1 1 1 Membrane transport protein Peptidase_C12 PF01088.16 EER26883.1 - 3.1e-70 235.7 0.0 3.8e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Fungal_trans_2 PF11951.3 EER26884.1 - 2.1e-09 36.4 2.9 4e-09 35.5 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26884.1 - 1.3e-07 31.4 14.2 2.3e-07 30.6 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_15 PF13429.1 EER26884.1 - 0.0067 15.5 1.3 0.24 10.4 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3865 PF12981.2 EER26884.1 - 0.17 11.6 0.8 0.5 10.1 0.6 1.6 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3865) Choline_kinase PF01633.15 EER26885.1 - 4.2e-63 212.7 0.0 8.5e-63 211.7 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EER26885.1 - 5.6e-13 48.1 0.0 1.3e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EER26885.1 - 1.3e-06 28.3 1.1 3.2e-06 27.0 0.2 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family MoeA_C PF03454.10 EER26885.1 - 0.12 12.4 0.3 17 5.4 0.1 2.5 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) HEAT_EZ PF13513.1 EER26886.1 - 2.7e-31 107.2 7.2 1.9e-13 50.4 0.0 10.9 10 1 1 11 11 11 3 HEAT-like repeat HEAT PF02985.17 EER26886.1 - 2.1e-28 95.8 16.6 1.6e-05 24.5 0.0 11.4 12 0 0 12 12 11 6 HEAT repeat HEAT_2 PF13646.1 EER26886.1 - 2.2e-24 85.5 0.3 6.6e-09 35.9 0.0 8.1 3 3 5 9 9 9 8 HEAT repeats Cnd1 PF12717.2 EER26886.1 - 3.3e-12 46.5 0.0 4e-06 26.8 0.0 5.6 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 EER26886.1 - 4.4e-10 38.8 1.7 0.042 12.5 0.0 5.6 7 0 0 7 7 7 3 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.2 EER26886.1 - 7.4e-10 39.0 0.0 0.021 15.1 0.0 5.7 5 2 3 8 8 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EER26886.1 - 3.1e-08 33.2 0.3 4.6 6.5 0.0 6.9 5 3 2 7 7 7 2 CLASP N terminal Adaptin_N PF01602.15 EER26886.1 - 1.5e-07 30.1 3.1 0.0081 14.5 0.2 3.7 3 2 0 4 4 4 2 Adaptin N terminal region Arm PF00514.18 EER26886.1 - 2.1e-06 27.3 1.0 0.31 10.9 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EER26886.1 - 2.7e-05 23.9 0.2 1.1 8.9 0.0 4.5 4 1 0 5 5 5 2 rRNA processing/ribosome biogenesis Xpo1 PF08389.7 EER26886.1 - 3.7e-05 23.6 0.0 0.017 15.0 0.0 4.2 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_PBS PF03130.11 EER26886.1 - 0.00019 21.5 0.2 0.29 11.7 0.0 4.0 3 0 0 3 3 2 1 PBS lyase HEAT-like repeat DUF3437 PF11919.3 EER26886.1 - 0.04 13.6 0.0 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DUF3385 PF11865.3 EER26886.1 - 0.055 13.3 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Syja_N PF02383.13 EER26887.1 - 2.4e-93 312.4 0.0 3.7e-93 311.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EER26887.1 - 1.8e-39 133.7 0.0 2.9e-39 132.9 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Mg_trans_NIPA PF05653.9 EER26888.1 - 2e-107 358.6 13.8 2.5e-107 358.2 9.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EER26888.1 - 3e-06 27.4 3.6 3e-06 27.4 2.5 3.6 2 1 1 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 EER26888.1 - 7.2e-05 22.8 6.8 7.2e-05 22.8 4.7 3.6 3 1 1 4 4 4 2 EamA-like transporter family LAB_N PF07578.6 EER26888.1 - 0.037 13.9 0.8 0.31 10.9 0.3 2.4 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain Acyl_transf_3 PF01757.17 EER26888.1 - 4.3 6.0 21.3 0.024 13.5 3.7 2.2 1 1 1 2 2 2 0 Acyltransferase family Glyco_transf_28 PF03033.15 EER26889.1 - 3.7e-20 72.1 0.0 2.6e-19 69.3 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EER26889.1 - 2.9e-06 26.1 0.0 5.1e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 EER26889.1 - 0.011 15.8 0.0 0.09 12.9 0.0 2.2 2 0 0 2 2 2 0 ATG C terminal domain Glyco_tran_28_C PF04101.11 EER26889.1 - 0.024 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain APH PF01636.18 EER26891.1 - 4.4e-16 59.3 0.0 1.4e-15 57.6 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER26891.1 - 1.3e-05 24.9 0.1 2.8e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EER26891.1 - 0.044 12.4 0.0 1.1 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Glyco_hydro_31 PF01055.21 EER26892.1 - 9.8e-120 400.3 0.2 3e-59 200.9 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 MFS_1 PF07690.11 EER26893.1 - 2.7e-19 69.0 39.5 3e-13 49.1 15.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER26893.1 - 1.2e-14 53.8 25.5 4.3e-14 51.9 17.7 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter ATP-synt_G PF04718.10 EER26895.1 - 1.4e-26 93.1 0.2 4.1e-26 91.6 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit DEAD PF00270.24 EER26896.1 - 1.3e-26 93.1 0.0 9e-25 87.1 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER26896.1 - 2.8e-22 78.3 0.4 1.6e-21 75.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER26896.1 - 1.3e-06 28.4 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EER26896.1 - 0.00023 19.7 0.0 0.028 12.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) T4SS-DNA_transf PF02534.9 EER26896.1 - 0.04 12.4 0.0 0.08 11.5 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Methyltransf_16 PF10294.4 EER26897.1 - 2.7e-22 79.0 0.0 4.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EER26897.1 - 0.00011 21.9 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER26897.1 - 0.002 18.7 0.0 0.0041 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER26897.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EER26897.1 - 0.04 14.3 0.0 0.42 11.1 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EER26897.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain VPS28 PF03997.7 EER26898.1 - 1.5e-60 204.0 0.0 1.8e-60 203.8 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Noc2 PF03715.8 EER26899.1 - 7e-121 402.6 0.1 1.4e-120 401.6 0.0 1.5 1 0 0 1 1 1 1 Noc2p family Piwi PF02171.12 EER26900.1 - 1.8e-77 260.2 0.1 2.5e-77 259.8 0.1 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EER26900.1 - 1.1e-16 59.9 0.0 2.1e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EER26900.1 - 1.4e-16 59.9 0.0 3.2e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 PAZ domain MoaC PF01967.16 EER26901.1 - 5.2e-42 142.7 0.1 8.9e-42 141.9 0.0 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EER26901.1 - 2.1e-34 117.9 0.0 2.1e-33 114.7 0.0 2.2 1 1 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EER26901.1 - 2.7e-21 76.4 0.0 4.6e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EER26901.1 - 0.00063 19.8 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EER26901.1 - 0.0021 18.0 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain AA_permease PF00324.16 EER26902.1 - 5.2e-142 473.5 39.3 6.4e-142 473.2 27.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER26902.1 - 2.3e-36 125.2 39.7 2.7e-36 125.0 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 EER26902.1 - 0.086 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) IKI3 PF04762.7 EER26903.1 - 0.0054 14.6 0.0 0.33 8.7 0.0 2.0 2 0 0 2 2 2 2 IKI3 family WD40 PF00400.27 EER26903.1 - 0.027 14.3 0.0 26 4.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribosomal_S25 PF03297.10 EER26904.1 - 4.4e-40 135.9 5.4 4.9e-40 135.8 3.8 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EER26904.1 - 0.0038 16.7 0.1 0.0052 16.2 0.1 1.2 1 0 0 1 1 1 1 DeoR-like helix-turn-helix domain Rrf2 PF02082.15 EER26904.1 - 0.021 14.9 0.1 0.032 14.3 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 EER26904.1 - 0.022 14.3 0.1 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_11 PF08279.7 EER26904.1 - 0.027 14.1 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 HTH domain TrmB PF01978.14 EER26904.1 - 0.031 13.9 0.3 0.039 13.6 0.2 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB FeoC PF09012.5 EER26904.1 - 0.037 13.7 0.4 0.093 12.4 0.0 1.7 1 1 1 2 2 2 0 FeoC like transcriptional regulator HTH_24 PF13412.1 EER26904.1 - 0.097 12.0 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.23 EER26905.1 - 1.8e-09 37.2 0.0 2.7e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.7 EER26906.1 - 4.1e-71 238.8 0.3 7.5e-71 237.9 0.1 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EER26906.1 - 4.6e-05 22.7 0.0 9.9e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.12 EER26906.1 - 0.0011 18.5 0.2 0.002 17.7 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EER26906.1 - 0.0073 15.5 0.1 0.019 14.1 0.0 1.8 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EER26906.1 - 0.0075 16.7 0.0 0.017 15.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EER26906.1 - 0.037 12.7 1.1 0.076 11.6 0.4 1.4 1 1 0 1 1 1 0 G-protein alpha subunit His_Phos_2 PF00328.17 EER26907.1 - 4.3e-21 75.6 0.0 4.2e-20 72.3 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_2 PF12706.2 EER26908.1 - 1.5e-31 109.4 0.1 2.9e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EER26908.1 - 2.2e-27 94.2 0.2 3.2e-26 90.5 0.0 2.5 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EER26908.1 - 1.6e-07 31.1 0.1 3.7e-07 29.9 0.1 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_1 PF00170.16 EER26909.1 - 3.3e-09 36.5 9.9 3.3e-09 36.5 6.8 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EER26909.1 - 0.0004 20.1 9.8 0.0004 20.1 6.8 3.1 3 0 0 3 3 3 1 Basic region leucine zipper PilO PF04350.8 EER26909.1 - 0.015 15.1 0.2 0.015 15.1 0.2 2.6 3 0 0 3 3 3 0 Pilus assembly protein, PilO Dus PF01207.12 EER26910.1 - 1.7e-58 197.8 0.0 3.9e-58 196.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.16 EER26910.1 - 0.018 14.0 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Fungal_trans_2 PF11951.3 EER26911.1 - 9.3e-28 96.8 1.6 1.2e-27 96.4 1.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26911.1 - 5.9e-07 29.2 9.3 1.3e-06 28.2 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIF PF01187.13 EER26912.1 - 3.1e-11 43.3 0.0 5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Macro PF01661.16 EER26913.1 - 3e-11 43.2 0.0 3.7e-07 30.0 0.0 2.3 2 1 0 2 2 2 2 Macro domain CENP-X PF09415.5 EER26914.1 - 8.6e-23 79.9 0.3 1.5e-22 79.2 0.2 1.4 1 0 0 1 1 1 1 CENP-S associating Centromere protein X HD_5 PF13487.1 EER26914.1 - 0.053 13.4 0.1 18 5.4 0.0 3.1 3 1 0 3 3 3 0 HD domain MCPVI PF02993.9 EER26914.1 - 7.6 6.6 8.3 8.5 6.4 4.4 2.0 1 1 2 3 3 3 0 Minor capsid protein VI CN_hydrolase PF00795.17 EER26915.1 - 1.5e-25 89.5 0.0 2.3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EER26915.1 - 2.6e-23 82.1 0.0 1.5e-22 79.6 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Cu_bind_like PF02298.12 EER26916.1 - 0.0063 16.2 0.5 0.079 12.7 0.4 2.1 1 1 0 1 1 1 1 Plastocyanin-like domain Mis12 PF05859.7 EER26917.1 - 8.3e-42 142.4 0.0 1.2e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein BCNT PF07572.7 EER26918.1 - 3.5e-27 94.1 0.1 3.5e-27 94.1 0.1 1.7 2 0 0 2 2 2 1 Bucentaur or craniofacial development BNR PF02012.15 EER26919.1 - 1.3 9.1 3.3 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 BNR/Asp-box repeat Zn_clus PF00172.13 EER26920.1 - 5.7e-06 26.1 10.6 5.7e-06 26.1 7.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EER26920.1 - 0.00026 19.7 1.2 0.0017 17.0 0.9 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3357 PF11837.3 EER26920.1 - 0.044 13.6 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) S-methyl_trans PF02574.11 EER26921.1 - 0.0043 16.3 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Rad51 PF08423.6 EER26922.1 - 8.8e-138 457.3 0.0 1.1e-137 457.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EER26922.1 - 2.2e-13 50.0 0.0 3.1e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EER26922.1 - 1.8e-09 37.6 0.2 4.6e-09 36.3 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 EER26922.1 - 5.6e-08 32.2 0.0 7.4e-08 31.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EER26922.1 - 2.2e-05 23.6 0.0 4.5e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.10 EER26922.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EER26922.1 - 0.085 11.6 0.1 0.21 10.3 0.0 1.6 2 0 0 2 2 2 0 PAXNEB protein PAN_4 PF14295.1 EER26924.1 - 5.3e-12 45.2 19.5 8.6e-05 22.1 0.3 4.5 4 0 0 4 4 4 4 PAN domain PAN_1 PF00024.21 EER26924.1 - 7.7e-12 44.7 29.3 4.7e-05 23.0 0.7 4.0 3 1 1 4 4 4 3 PAN domain PAN_3 PF08277.7 EER26924.1 - 0.0006 19.3 15.0 0.058 13.0 0.2 3.8 3 1 0 3 3 3 3 PAN-like domain MANEC PF07502.9 EER26924.1 - 0.00065 19.6 25.4 0.037 14.0 1.1 3.9 2 1 1 4 4 4 3 MANEC domain 2OG-FeII_Oxy_3 PF13640.1 EER26925.1 - 1.8e-05 25.1 0.0 3.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EER26925.1 - 0.015 15.5 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PAN_3 PF08277.7 EER26926.1 - 9.3e-13 47.6 12.1 2.7e-07 30.0 0.1 4.0 3 1 1 4 4 4 3 PAN-like domain PAN_1 PF00024.21 EER26926.1 - 1.1e-11 44.3 26.5 1.4e-05 24.7 4.1 3.9 3 2 1 4 4 4 3 PAN domain PAN_4 PF14295.1 EER26926.1 - 1.2e-05 24.9 24.6 0.002 17.8 0.6 4.7 4 0 0 4 4 4 3 PAN domain MANEC PF07502.9 EER26926.1 - 0.0011 18.9 1.3 0.0011 18.9 0.9 3.7 3 1 0 3 3 3 2 MANEC domain p450 PF00067.17 EER26927.1 - 4.7e-70 236.3 0.0 5.7e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EER26928.1 - 3e-46 157.7 15.6 3.9e-46 157.3 10.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER26928.1 - 3e-11 42.5 4.1 3e-11 42.5 2.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EER26928.1 - 1.1e-09 37.0 3.6 1.6e-09 36.5 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EER26928.1 - 0.011 13.9 5.8 0.019 13.0 4.0 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector WD40 PF00400.27 EER26929.1 - 1.5e-06 27.8 1.8 1 9.3 0.0 5.1 4 0 0 4 4 4 2 WD domain, G-beta repeat NACHT PF05729.7 EER26929.1 - 1e-05 25.2 0.0 3.3e-05 23.5 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EER26929.1 - 0.0015 18.5 0.0 0.0045 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EER26929.1 - 0.017 14.2 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EER26929.1 - 0.042 13.6 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain APS_kinase PF01583.15 EER26929.1 - 0.33 10.5 0.0 0.86 9.2 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_30 PF13604.1 EER26929.1 - 0.62 9.6 0.0 1.1 8.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fructosamin_kin PF03881.9 EER26930.1 - 9.2e-30 103.6 0.0 1.1e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EER26930.1 - 2.4e-06 27.4 0.3 3.6e-06 26.8 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EER26930.1 - 0.032 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EER26930.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DIOX_N PF14226.1 EER26931.1 - 2.4e-10 40.9 0.0 4.2e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EER26931.1 - 4.5e-09 36.4 0.0 8.8e-08 32.3 0.0 2.2 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Metallophos PF00149.23 EER26932.1 - 3.2e-37 127.8 0.0 3.6e-32 111.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ctr PF04145.10 EER26933.1 - 2.7e-43 147.4 0.7 3.4e-43 147.1 0.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF1673 PF07895.6 EER26933.1 - 0.013 15.0 0.0 0.063 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF4131 PF13567.1 EER26933.1 - 3.8 6.8 5.8 34 3.7 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Smg4_UPF3 PF03467.10 EER26934.1 - 8.2e-23 81.2 0.2 5.3e-22 78.6 0.0 2.4 2 1 0 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.17 EER26934.1 - 1.4e-09 37.4 0.0 1.8e-08 33.9 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER26934.1 - 2.1e-07 30.6 0.1 5.3e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER26934.1 - 3.3e-07 30.1 0.0 1.1e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Radical_SAM PF04055.16 EER26935.1 - 8.7e-24 84.5 0.1 1.9e-23 83.4 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EER26935.1 - 7.6e-23 80.3 0.1 2.4e-22 78.7 0.0 2.0 2 0 0 2 2 2 1 Wyosine base formation Flavodoxin_1 PF00258.20 EER26935.1 - 1.7e-09 37.8 0.1 1.9e-07 31.1 0.0 2.4 1 1 0 1 1 1 1 Flavodoxin Pro_dh PF01619.13 EER26936.1 - 2.6e-39 135.0 3.5 3.2e-39 134.7 2.4 1.0 1 0 0 1 1 1 1 Proline dehydrogenase OCD_Mu_crystall PF02423.10 EER26937.1 - 9.8e-16 57.4 0.0 2.6e-14 52.7 0.0 2.5 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EER26937.1 - 2.9e-06 27.3 0.0 1.4e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Zn_clus PF00172.13 EER26938.1 - 6.8e-06 25.8 10.3 1.1e-05 25.2 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EER26938.1 - 0.015 14.2 1.1 3.6 6.3 0.1 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain Mito_fiss_reg PF05308.6 EER26938.1 - 0.72 9.1 3.6 1.5 8.1 2.5 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator MFS_1 PF07690.11 EER26939.1 - 3.4e-38 131.2 52.4 1.6e-37 129.0 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CDC45 PF02724.9 EER26939.1 - 7.2 4.5 8.2 9.9 4.0 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Aldedh PF00171.17 EER26940.1 - 5.2e-188 625.0 0.1 5.9e-188 624.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EER26940.1 - 0.085 12.0 0.0 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Pyridox_oxidase PF01243.15 EER26941.1 - 3.6e-05 23.6 0.0 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Flavin_Reduct PF01613.13 EER26941.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 1 0 1 1 1 0 Flavin reductase like domain DUF1446 PF07287.6 EER26942.1 - 7.1e-127 422.8 0.1 8.4e-127 422.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Mre11_DNA_bind PF04152.9 EER26943.1 - 7.6e-59 198.4 0.1 7.6e-59 198.4 0.0 2.2 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EER26943.1 - 1.5e-24 86.4 1.4 2.3e-24 85.9 1.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER26943.1 - 5.6e-05 23.0 0.0 0.00016 21.5 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF837 PF05769.6 EER26943.1 - 0.023 14.2 0.4 0.023 14.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF837) Metallophos_3 PF14582.1 EER26943.1 - 0.063 12.4 0.0 0.15 11.1 0.0 1.5 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily Dicty_REP PF05086.7 EER26943.1 - 6.3 4.4 5.6 16 3.0 3.9 1.6 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein F-box-like PF12937.2 EER26944.1 - 5.6e-09 35.5 0.1 1.2e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER26944.1 - 1.6e-08 33.9 0.6 3.5e-08 32.8 0.1 1.8 2 0 0 2 2 2 1 F-box domain Glyco_hydro_72 PF03198.9 EER26945.1 - 1.1e-120 402.4 0.4 1.4e-120 402.0 0.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EER26945.1 - 1.5e-05 24.3 0.1 0.0013 18.0 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EER26945.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain MAS20 PF02064.10 EER26946.1 - 1.2e-18 67.2 0.3 2.6e-18 66.0 0.2 1.5 1 1 0 1 1 1 1 MAS20 protein import receptor Vps51 PF08700.6 EER26947.1 - 3.4e-17 62.0 1.7 3.4e-17 62.0 1.2 2.2 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 EER26947.1 - 0.0094 15.8 2.9 0.0099 15.7 0.1 2.4 2 1 1 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Rootletin PF15035.1 EER26947.1 - 0.092 12.7 9.4 0.035 14.1 0.8 2.3 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Baculo_PEP_C PF04513.7 EER26947.1 - 1.2 8.9 5.6 0.49 10.2 0.6 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ABC_tran PF00005.22 EER26949.1 - 6.3e-23 81.5 0.0 1.4e-11 44.8 0.0 3.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EER26949.1 - 3.6e-12 46.8 0.2 0.0012 18.8 0.0 3.3 3 0 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 EER26949.1 - 1.4e-05 24.9 0.0 0.042 13.7 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EER26949.1 - 0.0015 17.6 0.0 2.3 7.1 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_13 PF13166.1 EER26949.1 - 0.46 8.8 0.1 0.67 8.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain CPSase_L_D2 PF02786.12 EER26950.1 - 6.1e-113 375.2 0.4 5.8e-84 280.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EER26950.1 - 1.5e-46 157.1 0.0 3.3e-46 156.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EER26950.1 - 2.2e-45 154.4 0.0 6.3e-45 152.9 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EER26950.1 - 5.2e-42 142.8 0.1 1e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 EER26950.1 - 1.6e-41 140.8 0.1 8.8e-20 70.8 0.0 3.3 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 EER26950.1 - 7.4e-41 138.7 0.0 1.7e-40 137.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EER26950.1 - 8.2e-37 126.7 0.2 2.7e-22 79.4 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain OTCace PF00185.19 EER26950.1 - 5.1e-29 101.1 0.0 1.5e-28 99.6 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 EER26950.1 - 1e-22 79.8 0.0 3.9e-22 77.9 0.0 2.1 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 EER26950.1 - 1.6e-21 76.3 0.1 1.5e-09 37.0 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EER26950.1 - 1.2e-17 64.0 0.6 1.3e-08 34.4 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EER26950.1 - 8e-16 57.8 0.2 6.3e-07 28.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EER26950.1 - 1.1e-06 28.6 0.4 0.017 15.0 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EER26950.1 - 4.7e-06 26.2 0.2 0.00014 21.3 0.1 2.4 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 EER26950.1 - 2.6e-05 23.7 0.1 0.0012 18.3 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EER26950.1 - 0.012 15.1 0.5 3.2 7.2 0.0 2.8 3 0 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain TrkA_N PF02254.13 EER26950.1 - 0.03 14.3 2.3 0.18 11.8 0.0 3.1 3 0 0 3 3 3 0 TrkA-N domain DJ-1_PfpI PF01965.19 EER26950.1 - 0.046 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family Ion_trans PF00520.26 EER26951.1 - 0.00012 21.4 27.4 0.00052 19.3 19.0 2.0 1 1 0 1 1 1 1 Ion transport protein DUF3693 PF12472.3 EER26951.1 - 0.065 12.8 0.4 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Phage related protein Synaptobrevin PF00957.16 EER26952.1 - 1.1e-32 111.4 0.0 1.5e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EER26952.1 - 7.6e-25 86.2 0.0 1.3e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 EER26952.1 - 0.063 13.5 0.3 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 SpoIIAA-like KOW PF00467.24 EER26953.1 - 2.1e-08 33.5 2.1 2.1e-08 33.5 1.5 1.7 2 0 0 2 2 2 1 KOW motif AT_hook PF02178.14 EER26954.1 - 0.11 12.2 15.8 0.11 12.2 2.6 3.4 2 0 0 2 2 2 0 AT hook motif zf-CCCH PF00642.19 EER26955.1 - 8.7e-07 28.4 1.5 8.7e-07 28.4 1.1 2.7 3 1 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Polyoma_lg_T_C PF06431.6 EER26955.1 - 4.7 5.7 10.2 0.06 11.9 1.3 1.9 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus CS PF04969.11 EER26956.1 - 1.7e-05 25.2 0.0 3.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 CS domain Snf7 PF03357.16 EER26957.1 - 4.7e-22 78.1 11.2 5e-22 78.0 6.0 1.9 1 1 1 2 2 2 1 Snf7 Hairpins PF04877.7 EER26957.1 - 0.09 12.1 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 HrpZ DUF826 PF05696.6 EER26957.1 - 0.47 10.6 4.1 1.1 9.3 2.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF826) MerR-DNA-bind PF09278.6 EER26957.1 - 1.3 9.5 15.8 6.8 7.1 1.0 4.3 5 0 0 5 5 5 0 MerR, DNA binding DUF4404 PF14357.1 EER26957.1 - 5.1 7.5 12.4 6.8 7.1 0.5 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) RRM_1 PF00076.17 EER26958.1 - 9.6e-16 57.1 0.0 1.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER26958.1 - 3e-13 49.5 0.0 4.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EER26958.1 - 1.3e-05 25.5 0.5 1.3e-05 25.5 0.3 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EER26958.1 - 2.7e-05 23.9 0.0 4.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP33 PF01430.14 EER26958.1 - 0.0089 15.1 0.5 0.012 14.7 0.0 1.4 2 0 0 2 2 2 1 Hsp33 protein CAP_N PF01213.14 EER26959.1 - 5.1 6.2 7.5 11 5.2 5.2 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF3007 PF11460.3 EER26962.1 - 0.03 14.3 0.9 0.56 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) PAT1 PF09770.4 EER26962.1 - 3.1 5.9 25.0 4.1 5.5 17.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BTB PF00651.26 EER26963.1 - 2.5e-18 66.0 0.0 5.2e-18 65.0 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Dynamin_N PF00350.18 EER26964.1 - 6.8e-35 120.3 0.0 1.2e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EER26964.1 - 6.8e-13 48.0 0.2 7.2e-12 44.6 0.0 2.3 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EER26964.1 - 1.1e-05 25.3 0.0 3.7e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER26964.1 - 0.0024 18.3 0.0 0.0089 16.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EER26964.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EER26964.1 - 0.059 13.6 0.1 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Glyco_hydro_75 PF07335.6 EER26965.1 - 8.3e-39 132.9 0.2 1.1e-38 132.5 0.1 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 adh_short PF00106.20 EER26966.1 - 5.4e-18 65.4 0.0 7.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER26966.1 - 2.8e-06 27.2 0.0 3.9e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER26966.1 - 3.8e-06 26.6 0.0 5.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF460 PF04312.8 EER26966.1 - 0.0015 18.0 0.1 0.0023 17.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF460) DUF1776 PF08643.5 EER26966.1 - 0.0036 16.5 0.0 0.0048 16.0 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Tubulin_2 PF13809.1 EER26966.1 - 0.016 14.1 0.0 0.031 13.2 0.0 1.4 2 0 0 2 2 2 0 Tubulin like ABC2_membrane PF01061.19 EER26967.1 - 2.1e-85 285.1 63.5 4.9e-48 163.0 17.2 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EER26967.1 - 1.8e-37 128.6 0.0 1.5e-18 67.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EER26967.1 - 1.1e-25 89.2 0.0 1.1e-25 89.2 0.0 3.0 3 0 0 3 3 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 EER26967.1 - 1.8e-11 43.7 44.4 9.5e-08 31.4 14.9 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EER26967.1 - 6.1e-07 29.0 0.1 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 EER26967.1 - 3e-06 27.2 0.0 8.7e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EER26967.1 - 5.9e-06 25.5 0.0 7.6e-05 21.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EER26967.1 - 3.4e-05 23.9 0.1 0.099 12.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EER26967.1 - 9.1e-05 23.2 0.0 0.034 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EER26967.1 - 0.00029 20.3 0.1 0.072 12.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EER26967.1 - 0.00036 20.5 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EER26967.1 - 0.0018 17.7 0.1 0.04 13.3 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 EER26967.1 - 0.0026 17.2 0.1 2.9 7.2 0.0 2.7 3 0 0 3 3 2 2 AAA-like domain AAA_33 PF13671.1 EER26967.1 - 0.0039 17.0 0.2 0.83 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EER26967.1 - 0.0042 17.0 2.9 0.048 13.6 0.1 3.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EER26967.1 - 0.0056 16.3 0.4 0.29 10.8 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EER26967.1 - 0.0062 16.0 0.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 EER26967.1 - 0.0085 16.0 1.0 0.04 13.8 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EER26967.1 - 0.0092 16.2 0.1 0.5 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EER26967.1 - 0.036 13.7 0.7 0.8 9.3 0.1 2.5 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EER26967.1 - 0.039 13.5 2.9 0.16 11.6 0.1 2.5 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EER26967.1 - 0.1 12.1 0.4 1 8.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain Shikimate_dh_N PF08501.6 EER26967.1 - 0.15 12.1 0.0 0.62 10.1 0.0 2.0 2 0 0 2 2 1 0 Shikimate dehydrogenase substrate binding domain MMR_HSR1 PF01926.18 EER26967.1 - 0.15 12.0 0.0 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase MFS_1 PF07690.11 EER26968.1 - 8.9e-35 120.0 21.3 3.2e-34 118.1 15.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NfeD PF01957.13 EER26968.1 - 2.7 8.1 0.0 2.7 8.1 0.0 3.9 3 2 1 4 4 4 0 NfeD-like C-terminal, partner-binding Acyl-CoA_dh_1 PF00441.19 EER26969.1 - 9e-39 132.9 6.5 1.6e-38 132.1 4.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EER26969.1 - 1.6e-21 76.9 0.0 5.2e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EER26969.1 - 9.2e-16 58.3 4.0 9.2e-16 58.3 2.8 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EER26969.1 - 6e-14 51.2 0.0 1.4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Glucosaminidase PF01832.15 EER26969.1 - 0.0013 18.8 0.2 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase CoA_transf_3 PF02515.12 EER26970.1 - 6.8e-34 116.7 0.3 1.1e-33 116.1 0.2 1.3 1 0 0 1 1 1 1 CoA-transferase family III DUF1275 PF06912.6 EER26971.1 - 1.9e-41 141.5 7.0 2.8e-41 141.0 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) VIT1 PF01988.14 EER26971.1 - 0.19 11.1 2.4 0.41 10.1 0.2 2.3 2 1 0 2 2 2 0 VIT family Fungal_trans_2 PF11951.3 EER26973.1 - 2.6e-43 148.1 0.1 5.1e-43 147.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER26973.1 - 0.00028 20.7 5.4 0.00092 19.0 3.7 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 EER26974.1 - 1.1e-48 165.0 0.1 7.3e-27 94.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EER26974.1 - 2.6e-36 125.4 40.6 2.1e-24 86.4 10.1 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EER26974.1 - 9.4e-10 38.0 1.7 0.0045 16.2 0.0 3.7 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER26974.1 - 9.8e-07 29.0 2.7 0.037 13.9 0.0 3.8 3 1 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EER26974.1 - 2.5e-06 26.9 0.1 0.0093 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EER26974.1 - 3.2e-06 27.2 0.3 0.035 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EER26974.1 - 1.2e-05 24.7 0.0 0.046 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EER26974.1 - 1.4e-05 25.5 0.1 0.0044 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EER26974.1 - 0.00018 21.0 4.6 0.023 14.1 0.0 2.7 3 0 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 EER26974.1 - 0.00032 20.6 0.0 0.083 12.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EER26974.1 - 0.00055 19.1 0.1 0.039 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EER26974.1 - 0.00056 20.1 1.8 0.058 13.5 0.0 3.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EER26974.1 - 0.00066 18.6 0.0 0.05 12.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 EER26974.1 - 0.00075 19.9 0.2 1.5 9.3 0.1 2.5 2 0 0 2 2 2 2 Miro-like protein ArgK PF03308.11 EER26974.1 - 0.00084 18.1 0.2 0.69 8.6 0.0 2.3 2 0 0 2 2 2 2 ArgK protein ATP_bind_1 PF03029.12 EER26974.1 - 0.0016 18.0 0.3 0.26 10.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EER26974.1 - 0.0021 17.7 0.0 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EER26974.1 - 0.0024 18.0 2.0 0.29 11.2 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER26974.1 - 0.0027 18.5 2.2 0.47 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EER26974.1 - 0.01 15.4 0.2 6.2 6.3 0.0 3.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EER26974.1 - 0.012 15.4 0.6 0.13 12.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EER26974.1 - 0.02 13.9 0.2 1.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 EER26974.1 - 0.023 14.5 0.3 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 EER26974.1 - 0.023 14.8 0.2 6.5 6.9 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Viral_helicase1 PF01443.13 EER26974.1 - 0.024 14.1 0.2 0.55 9.7 0.0 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase ABC_ATPase PF09818.4 EER26974.1 - 0.024 13.2 1.5 0.23 9.9 0.0 2.8 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF815 PF05673.8 EER26974.1 - 0.029 13.3 0.0 4 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EER26974.1 - 0.031 13.7 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EER26974.1 - 0.038 12.8 1.7 0.43 9.3 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 EER26974.1 - 0.055 13.3 0.2 0.4 10.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 EER26974.1 - 0.055 13.7 1.0 3.3 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EER26974.1 - 0.061 13.0 2.0 7.6 6.2 0.2 2.7 2 0 0 2 2 2 0 NTPase Rad17 PF03215.10 EER26974.1 - 0.068 11.8 0.3 0.35 9.5 0.1 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF87 PF01935.12 EER26974.1 - 0.068 12.9 0.9 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 MobB PF03205.9 EER26974.1 - 0.087 12.5 3.0 1.6 8.4 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 EER26974.1 - 0.11 11.9 0.0 5 6.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Adeno_IVa2 PF02456.10 EER26974.1 - 0.15 10.6 0.1 2.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein TrwB_AAD_bind PF10412.4 EER26974.1 - 0.15 10.6 0.2 6.6 5.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 EER26974.1 - 0.22 10.9 3.1 0.62 9.4 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EER26974.1 - 0.27 10.8 2.7 0.8 9.3 0.0 2.9 3 0 0 3 3 2 0 NACHT domain PduV-EutP PF10662.4 EER26974.1 - 0.38 10.2 1.9 0.94 8.9 0.0 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AMP-binding PF00501.23 EER26975.1 - 0 1423.6 0.0 7.2e-89 298.0 0.0 5.5 6 0 0 6 6 6 5 AMP-binding enzyme Condensation PF00668.15 EER26975.1 - 0 1349.2 0.0 2.8e-56 190.5 0.0 10.7 10 1 0 10 10 10 10 Condensation domain PP-binding PF00550.20 EER26975.1 - 4.5e-93 305.5 2.7 3.1e-12 46.5 0.1 9.0 8 0 0 8 8 8 8 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EER26975.1 - 3.7e-22 79.0 0.1 5.6e-05 23.9 0.0 5.9 5 0 0 5 5 5 5 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EER26975.1 - 2.2e-07 29.7 0.0 0.069 11.5 0.0 4.5 5 0 0 5 5 5 3 Transferase family HxxPF_rpt PF13745.1 EER26975.1 - 0.00025 21.2 0.1 0.06 13.6 0.0 4.0 4 0 0 4 4 4 1 HxxPF-repeated domain DUF808 PF05661.7 EER26975.1 - 6.8 5.4 0.1 24 3.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF808) BCIP PF13862.1 EER26977.1 - 1.9e-70 236.3 0.3 2.3e-70 236.0 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.16 EER26978.1 - 1.8e-09 37.5 0.4 1.2e-06 28.4 0.0 3.1 2 1 0 2 2 2 2 Chorismate mutase type II DUF1857 PF08982.6 EER26978.1 - 0.042 13.4 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) Plasmod_dom_1 PF09715.5 EER26978.1 - 0.096 12.6 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Sad1_UNC PF07738.8 EER26979.1 - 2e-15 56.8 0.0 4.2e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal WD40 PF00400.27 EER26980.1 - 7.4e-36 120.7 11.4 1e-09 37.8 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EER26980.1 - 1.2e-07 30.3 5.2 0.067 11.3 0.0 4.6 3 2 2 5 5 5 4 Nucleoporin Nup120/160 APG6 PF04111.7 EER26980.1 - 0.0033 16.5 1.2 0.0051 15.9 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EER26980.1 - 0.029 14.2 6.8 0.047 13.5 4.7 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EER26980.1 - 0.21 11.1 2.2 0.49 9.9 1.5 1.5 1 0 0 1 1 1 0 IncA protein Peptidase_S8 PF00082.17 EER26981.1 - 1.4e-44 152.3 9.1 1.8e-44 151.9 6.3 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER26981.1 - 1.7e-17 63.7 0.0 3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Kinesin PF00225.18 EER26982.1 - 1.3e-91 306.8 0.0 1.3e-91 306.8 0.0 2.9 3 0 0 3 3 3 1 Kinesin motor domain Reo_sigmaC PF04582.7 EER26982.1 - 0.017 14.3 76.5 0.0085 15.3 4.6 8.4 4 1 4 8 8 8 0 Reovirus sigma C capsid protein Glycos_transf_1 PF00534.15 EER26983.1 - 8.1e-32 110.0 0.0 3.7e-30 104.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EER26983.1 - 1.3e-10 41.3 0.0 1.9e-05 24.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EER26983.1 - 1.9e-08 34.5 0.0 6.9e-07 29.4 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EER26983.1 - 2e-07 31.3 10.0 1.4e-06 28.5 6.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EER26983.1 - 4.6e-05 23.6 0.0 8.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4095 PF13338.1 EER26983.1 - 0.1 12.7 0.1 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) ERCC4 PF02732.10 EER26985.1 - 7.2e-28 97.1 0.1 1.3e-26 93.0 0.0 2.4 2 0 0 2 2 2 1 ERCC4 domain Cwf_Cwc_15 PF04889.7 EER26985.1 - 0.011 15.4 10.3 0.02 14.5 7.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MFS_1 PF07690.11 EER26986.1 - 1.7e-18 66.4 15.9 1.7e-18 66.4 11.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EER26986.1 - 4.9e-07 29.2 0.4 4.9e-07 29.2 0.3 1.7 2 0 0 2 2 2 1 Nodulin-like IPK PF03770.11 EER26987.1 - 2.1e-58 197.2 0.0 3.4e-58 196.5 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 EER26987.1 - 0.041 13.5 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 NMT1 PF09084.6 EER26988.1 - 1.1e-76 257.1 0.0 1.4e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EER26988.1 - 1.2e-08 34.6 0.3 0.017 14.5 0.0 3.5 2 1 2 4 4 4 3 NMT1-like family Phosphonate-bd PF12974.2 EER26988.1 - 0.053 12.8 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein HIG_1_N PF04588.8 EER26988.1 - 0.074 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region PBP_like PF12727.2 EER26988.1 - 0.14 11.1 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 PBP superfamily domain LRR_4 PF12799.2 EER26989.1 - 7.4e-29 98.8 47.3 2.3e-07 30.2 0.1 8.0 6 2 0 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER26989.1 - 8.3e-23 79.9 43.0 1.8e-06 27.5 5.6 6.8 4 1 3 7 7 7 7 Leucine rich repeat LRR_6 PF13516.1 EER26989.1 - 4.2e-09 35.5 45.9 0.13 12.3 0.3 11.8 10 3 2 12 12 12 6 Leucine Rich repeat LRR_1 PF00560.28 EER26989.1 - 4.2e-09 35.1 50.2 0.86 9.8 0.1 14.1 11 3 2 13 13 13 5 Leucine Rich Repeat LRR_9 PF14580.1 EER26989.1 - 2.8e-08 33.5 5.5 0.04 13.4 0.3 4.2 2 1 2 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 EER26989.1 - 0.0034 17.3 52.9 1.8 9.1 0.3 13.0 13 1 0 13 13 13 3 Leucine rich repeat Clathrin PF00637.15 EER26991.1 - 2.5e-20 72.5 1.5 1.9e-18 66.4 0.7 2.6 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 EER26991.1 - 1.2e-19 69.8 0.1 2.9e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 EER26991.1 - 0.00025 20.6 6.4 0.00052 19.6 4.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EER26991.1 - 0.017 14.9 6.8 0.034 13.9 4.7 1.5 1 0 0 1 1 1 0 Ring finger domain TPR_11 PF13414.1 EER26991.1 - 0.019 14.5 0.0 0.083 12.5 0.0 2.1 1 0 0 1 1 1 0 TPR repeat zf-C3HC4_2 PF13923.1 EER26991.1 - 0.02 14.9 5.9 0.038 14.0 4.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Leuk-A4-hydro_C PF09127.6 EER26991.1 - 0.033 13.8 0.7 0.41 10.2 0.1 2.3 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal zf-rbx1 PF12678.2 EER26991.1 - 0.053 13.6 3.8 0.11 12.6 2.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger TPR_2 PF07719.12 EER26991.1 - 0.059 13.3 0.0 0.4 10.7 0.0 2.5 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 EER26991.1 - 0.18 11.6 0.8 0.37 10.6 0.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EER26991.1 - 0.25 11.1 2.2 0.65 9.8 1.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EER26991.1 - 0.45 10.2 6.5 0.86 9.3 4.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 EER26991.1 - 0.53 10.2 8.5 1.8 8.5 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.16 EER26993.1 - 6.9e-29 100.0 0.0 1.5e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EER26993.1 - 2.3e-08 33.8 38.2 1.8e-05 24.6 8.8 2.7 2 1 0 2 2 2 2 Chitin recognition protein RNA_pol_3_Rpc31 PF11705.3 EER26993.1 - 3.5 7.4 29.3 7.4 6.4 20.3 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2435 PF10363.4 EER26994.1 - 9.7e-26 89.5 0.7 3.9e-25 87.5 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EER26994.1 - 3.4e-08 32.8 0.0 6.8e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DBR1 PF05011.8 EER26995.1 - 1.3e-46 158.1 0.0 3.7e-46 156.6 0.0 1.8 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EER26995.1 - 7.7e-08 31.9 1.4 1.8e-07 30.7 0.9 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GRP PF07172.6 EER26995.1 - 1.2 9.6 17.4 2.8 8.4 12.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family zf-ZPR1 PF03367.8 EER26996.1 - 2.4e-101 335.6 0.0 1.1e-49 167.6 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Dynactin_p62 PF05502.8 EER26996.1 - 0.06 12.1 0.5 0.099 11.3 0.0 1.5 2 0 0 2 2 2 0 Dynactin p62 family zinc-ribbons_6 PF07191.7 EER26996.1 - 0.54 10.0 3.5 0.81 9.5 0.2 2.6 3 0 0 3 3 3 0 zinc-ribbons UPF0547 PF10571.4 EER26996.1 - 4.1 7.1 12.0 3.5 7.4 0.1 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Pro_isomerase PF00160.16 EER26997.1 - 3.5e-36 124.7 0.0 1.5e-35 122.6 0.0 1.7 1 1 1 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 EER26998.1 - 1.2e-14 54.5 0.1 3.7e-14 52.9 0.0 1.8 2 1 1 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Fer2_3 PF13085.1 EER26999.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain SicP-binding PF09119.5 EER26999.1 - 0.095 12.4 0.2 3.6 7.3 0.0 2.2 1 1 1 2 2 2 0 SicP binding tRNA_int_end_N2 PF12928.2 EER27000.1 - 2e-32 110.4 0.0 3.4e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EER27000.1 - 0.005 16.3 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Skp1_POZ PF03931.10 EER27001.1 - 5.3e-11 42.4 0.0 1.2e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain adh_short PF00106.20 EER27002.1 - 6.7e-25 87.9 0.8 1.2e-21 77.3 0.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER27002.1 - 6.1e-15 55.6 0.5 9.2e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER27002.1 - 2.4e-09 37.1 1.3 1.3e-08 34.7 0.9 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EER27002.1 - 4e-06 25.9 0.1 8.1e-06 24.9 0.1 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EER27002.1 - 1.7e-05 23.9 0.1 0.013 14.3 0.0 2.2 1 1 1 2 2 2 2 Polysaccharide biosynthesis protein Epimerase PF01370.16 EER27002.1 - 4.6e-05 22.9 0.1 0.00097 18.6 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EER27002.1 - 0.00029 20.9 3.4 0.057 13.4 0.0 3.0 3 0 0 3 3 3 2 NADH(P)-binding DNA_pol3_tau_4 PF12168.3 EER27002.1 - 0.028 14.8 0.3 0.062 13.7 0.2 1.6 1 0 0 1 1 1 0 DNA polymerase III subunits tau domain IV DnaB-binding HLH PF00010.21 EER27002.1 - 0.03 13.9 0.0 0.078 12.6 0.0 1.6 1 1 0 1 1 1 0 Helix-loop-helix DNA-binding domain Shikimate_DH PF01488.15 EER27002.1 - 0.065 13.3 0.1 0.77 9.8 0.0 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EER27003.1 - 1.2e-41 141.7 0.1 5.2e-41 139.6 0.0 2.0 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EER27003.1 - 1.2e-27 95.2 1.1 2.7e-27 94.1 0.8 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EER27003.1 - 7.4e-21 74.0 0.0 1.7e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EER27003.1 - 5.3e-19 67.3 0.9 5.3e-19 67.3 0.6 2.8 3 0 0 3 3 3 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EER27003.1 - 0.00014 22.0 0.1 0.00052 20.2 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EER27003.1 - 0.0053 17.1 0.1 0.32 11.4 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EER27003.1 - 0.0059 16.7 0.0 0.017 15.2 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glt_symporter PF03616.9 EER27003.1 - 0.084 11.3 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF3192 PF11399.3 EER27003.1 - 0.13 12.2 0.2 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) DUF2419 PF10343.4 EER27004.1 - 4.3e-142 472.4 0.1 5.3e-142 472.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Interfer-bind PF09294.5 EER27004.1 - 0.14 12.1 0.1 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III ORC6 PF05460.8 EER27005.1 - 3.1e-60 204.1 0.0 3.8e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Amidase PF01425.16 EER27006.1 - 1.5e-89 300.8 0.0 1.8e-89 300.6 0.0 1.0 1 0 0 1 1 1 1 Amidase DNA_pol_delta_4 PF04081.8 EER27007.1 - 1.2e-25 90.1 0.2 1.8e-25 89.5 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 HrpE PF06188.7 EER27007.1 - 0.1 12.3 1.9 0.15 11.7 1.3 1.2 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E TFIIF_alpha PF05793.7 EER27007.1 - 1.2 7.4 6.1 1.5 7.1 4.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CFEM PF05730.6 EER27008.1 - 2.8e-16 59.1 5.4 3.7e-16 58.6 3.7 1.2 1 0 0 1 1 1 1 CFEM domain PT PF04886.7 EER27008.1 - 2.8e-07 29.7 37.1 4.5e-06 25.8 25.3 3.0 1 1 0 1 1 1 1 PT repeat Trypan_PARP PF05887.6 EER27008.1 - 0.094 12.5 16.0 0.17 11.6 11.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MGC-24 PF05283.6 EER27008.1 - 8.2 6.1 17.9 19 5.0 12.4 1.6 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Caveolin PF01146.12 EER27009.1 - 0.016 14.7 0.9 0.021 14.4 0.6 1.1 1 0 0 1 1 1 0 Caveolin Ank_2 PF12796.2 EER27010.1 - 1.6e-14 54.0 0.0 1.5e-06 28.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EER27010.1 - 4e-13 48.4 0.1 0.0054 16.4 0.0 4.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EER27010.1 - 3.1e-07 29.9 0.5 0.09 13.0 0.0 4.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EER27010.1 - 6.3e-07 29.7 0.2 0.2 12.2 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER27010.1 - 3.2e-06 27.2 0.2 0.0005 20.2 0.0 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) ATP-grasp_2 PF08442.5 EER27011.1 - 1e-08 34.8 0.0 1.5e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain CoA_binding PF02629.14 EER27012.1 - 9.8e-19 67.6 0.1 2.9e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Citrate_synt PF00285.16 EER27012.1 - 2.3e-18 66.0 0.0 8.9e-16 57.5 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EER27012.1 - 4.9e-16 58.6 0.1 9.3e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EER27012.1 - 3.4e-08 33.1 0.0 4.2e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ank_2 PF12796.2 EER27013.1 - 3.5e-53 177.9 1.0 1.4e-10 41.3 0.1 5.6 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EER27013.1 - 1e-40 135.5 7.7 5.2e-05 22.8 0.0 9.4 9 1 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 EER27013.1 - 7.7e-40 134.5 4.3 1.7e-08 34.7 0.0 7.4 5 2 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER27013.1 - 3.1e-36 122.5 4.5 1.2e-08 34.9 0.0 7.4 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER27013.1 - 2.1e-33 111.0 4.4 0.0073 16.4 0.0 9.9 9 1 0 9 9 9 7 Ankyrin repeat F-box-like PF12937.2 EER27013.1 - 0.0036 16.9 0.1 0.0036 16.9 0.1 2.4 3 1 0 3 3 3 1 F-box-like RNase_P_Rpp14 PF01900.14 EER27015.1 - 1.9e-36 124.1 0.0 2.6e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family CUE PF02845.11 EER27015.1 - 0.15 11.5 0.1 18 4.9 0.1 2.3 2 0 0 2 2 2 0 CUE domain ATP_bind_1 PF03029.12 EER27016.1 - 5.6e-76 255.2 0.0 7e-76 254.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EER27016.1 - 0.00038 21.2 1.6 0.0018 19.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EER27016.1 - 0.00057 19.4 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EER27016.1 - 0.00067 18.5 0.0 0.0014 17.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EER27016.1 - 0.0013 18.1 0.0 0.003 16.9 0.0 1.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 EER27016.1 - 0.0039 17.1 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EER27016.1 - 0.0079 15.7 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 EER27016.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EER27016.1 - 0.022 14.9 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EER27016.1 - 0.034 14.0 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EER27016.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 EER27016.1 - 0.05 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.1 EER27016.1 - 0.056 13.4 0.0 11 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.7 EER27016.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Fer4_NifH PF00142.13 EER27016.1 - 0.12 11.5 0.3 0.35 10.0 0.2 1.8 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_18 PF13238.1 EER27016.1 - 0.18 12.0 0.6 0.71 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EER27017.1 - 7.2e-07 28.8 0.1 0.00061 19.5 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ThiF PF00899.16 EER27018.1 - 5e-08 32.8 0.0 1.4e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 ThiF family MotCF PF09158.5 EER27018.1 - 0.05 13.2 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal MoeZ_MoeB PF05237.8 EER27018.1 - 0.13 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 MoeZ/MoeB domain LtrA PF06772.6 EER27019.1 - 1.3e-23 83.4 23.4 3e-23 82.3 11.2 2.1 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) DUF998 PF06197.8 EER27019.1 - 0.2 10.9 16.9 0.12 11.6 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF998) GMC_oxred_N PF00732.14 EER27020.1 - 6.5e-64 215.9 0.0 8e-64 215.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EER27020.1 - 2.5e-11 44.0 0.0 4.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EER27020.1 - 3.7e-07 29.3 0.0 0.00024 20.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EER27020.1 - 8.9e-07 28.1 1.9 8.8e-06 24.8 1.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EER27020.1 - 0.0031 16.4 0.1 0.0046 15.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EER27020.1 - 0.033 12.6 0.0 0.34 9.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_8 PF13450.1 EER27020.1 - 0.043 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER27020.1 - 0.058 13.2 0.1 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3089 PF11288.3 EER27022.1 - 0.018 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 EER27022.1 - 0.023 14.2 0.0 0.049 13.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein An_peroxidase PF03098.10 EER27023.1 - 3.7e-97 325.9 0.0 1.3e-76 258.1 0.0 2.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EER27023.1 - 4.3e-07 28.8 0.0 4.8e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Asp PF00026.18 EER27024.1 - 2.1e-11 43.6 0.0 3.8e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EER27024.1 - 0.022 14.0 3.8 0.047 13.0 2.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.1 EER27024.1 - 0.12 12.0 0.4 0.44 10.2 0.3 1.9 1 1 0 1 1 1 0 TMEM154 protein family zf-C3HC4_3 PF13920.1 EER27025.1 - 3.6e-08 32.9 12.1 5.9e-08 32.2 8.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER27027.1 - 0.0002 21.0 1.1 0.00034 20.2 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EER27027.1 - 0.00028 20.4 0.5 0.00044 19.8 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER27027.1 - 0.0048 16.6 0.7 0.0098 15.7 0.5 1.5 1 0 0 1 1 1 1 Ring finger domain DZR PF12773.2 EER27027.1 - 0.0065 16.2 0.3 0.011 15.5 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-NADH-PPase PF09297.6 EER27027.1 - 0.0069 15.8 1.0 0.011 15.1 0.7 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_2 PF13923.1 EER27027.1 - 0.0077 16.2 0.5 0.014 15.4 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EER27027.1 - 0.028 14.2 0.6 0.057 13.2 0.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CHY PF05495.7 EER27027.1 - 0.12 12.5 0.2 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 CHY zinc finger zf-C3HC4 PF00097.20 EER27027.1 - 0.4 10.3 2.0 0.35 10.5 0.4 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) XAP5 PF04921.9 EER27028.1 - 5.7e-79 265.0 0.0 9e-79 264.4 0.0 1.3 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.1 EER27028.1 - 0.018 15.2 2.7 0.03 14.5 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Fip1 PF05182.8 EER27029.1 - 2e-21 74.9 2.0 3.5e-21 74.1 1.4 1.4 1 0 0 1 1 1 1 Fip1 motif Cpn10 PF00166.16 EER27030.1 - 2.8e-27 94.4 0.0 3.2e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Nucleoporin_FG PF13634.1 EER27032.1 - 4.4e-06 26.9 87.0 0.067 13.4 28.6 3.5 2 1 1 3 3 3 2 Nucleoporin FG repeat region DUF1664 PF07889.7 EER27032.1 - 0.16 11.7 0.7 2.6 7.8 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) WD40 PF00400.27 EER27033.1 - 1.4e-10 40.5 10.2 0.0076 16.1 0.0 7.3 6 2 0 6 6 6 4 WD domain, G-beta repeat Lactonase PF10282.4 EER27033.1 - 0.0098 15.0 0.0 0.082 11.9 0.0 1.5 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HAD_2 PF13419.1 EER27035.1 - 1.3e-13 51.5 0.0 1.7e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EER27035.1 - 2.2e-06 28.2 0.0 3.5e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER27035.1 - 3.3e-06 26.7 0.0 7.7e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.7 EER27035.1 - 0.0028 17.1 0.0 0.0088 15.5 0.0 1.8 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) TPR_11 PF13414.1 EER27036.1 - 5.2e-13 48.4 3.2 3.3e-11 42.6 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EER27036.1 - 3e-06 26.5 1.9 0.032 13.8 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EER27036.1 - 0.00014 21.5 2.4 0.74 9.8 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EER27036.1 - 0.00034 20.5 2.0 0.0026 17.6 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EER27036.1 - 0.032 14.3 0.3 0.074 13.2 0.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EER27036.1 - 0.051 14.2 1.8 22 6.0 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EER27036.1 - 0.11 12.3 0.2 3.5 7.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3112 PF11309.3 EER27037.1 - 4.6e-45 153.2 0.4 4.6e-45 153.2 0.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) DUF1469 PF07332.6 EER27037.1 - 0.02 14.6 0.7 0.02 14.6 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Metallophos PF00149.23 EER27038.1 - 5.4e-36 123.8 0.2 6.3e-36 123.6 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rib_5-P_isom_A PF06026.9 EER27040.1 - 2.4e-38 131.1 0.0 4e-36 123.9 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EER27040.1 - 0.023 14.3 0.0 4.3 6.9 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain PI31_Prot_N PF11566.3 EER27041.1 - 2.8e-33 114.7 0.0 3.6e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EER27041.1 - 9.8e-18 64.5 19.6 9.8e-18 64.5 13.6 3.0 3 0 0 3 3 3 1 PI31 proteasome regulator DUF2183 PF09949.4 EER27042.1 - 1.4e-32 111.5 0.0 7.8e-32 109.1 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EER27042.1 - 0.092 12.3 0.0 0.22 11.1 0.0 1.5 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF2064 PF09837.4 EER27043.1 - 7.8e-14 51.3 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) Glyco_tranf_2_3 PF13641.1 EER27043.1 - 7.3e-05 22.6 0.1 0.0002 21.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 HTH_23 PF13384.1 EER27043.1 - 0.018 14.6 0.1 0.065 12.9 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Phage_base_V PF04717.7 EER27043.1 - 0.08 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Phage-related baseplate assembly protein DUF3641 PF12345.3 EER27044.1 - 7.6e-50 168.2 0.0 1.3e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.16 EER27044.1 - 3.9e-09 36.8 0.1 2.3e-08 34.3 0.1 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Fer4_12 PF13353.1 EER27044.1 - 2.6e-05 24.3 0.3 5.6e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EER27044.1 - 0.00011 22.2 0.3 0.00025 21.0 0.2 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain SPASM PF13186.1 EER27044.1 - 0.0041 17.4 0.2 0.016 15.5 0.1 2.0 1 0 0 1 1 1 1 Iron-sulfur cluster-binding domain Cytochrom_C550 PF14495.1 EER27044.1 - 0.087 12.2 1.2 0.19 11.1 0.6 1.7 1 1 1 2 2 2 0 Cytochrome c-550 domain p450 PF00067.17 EER27045.1 - 5.5e-14 51.5 0.0 2.8e-13 49.2 0.0 2.0 3 0 0 3 3 3 1 Cytochrome P450 RESP18 PF14948.1 EER27045.1 - 0.072 13.1 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 RESP18 domain FA_hydroxylase PF04116.8 EER27046.1 - 1.9e-10 41.1 11.7 1.9e-10 41.1 8.1 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UvdE PF03851.9 EER27047.1 - 1.4e-111 371.9 0.0 1.8e-111 371.5 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE Cu_amine_oxid PF01179.15 EER27048.1 - 6.2e-145 483.0 0.0 7.5e-145 482.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EER27048.1 - 1.1e-11 44.5 0.4 2.7e-10 40.1 0.0 2.6 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EER27048.1 - 0.00086 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Aldedh PF00171.17 EER27049.1 - 2.9e-164 546.7 0.6 3.3e-164 546.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EER27049.1 - 0.02 13.6 0.0 0.034 12.8 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Amino_oxidase PF01593.19 EER27051.1 - 3.2e-47 161.6 0.0 7.2e-30 104.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EER27051.1 - 2.2e-14 53.2 0.1 4.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EER27051.1 - 4.4e-06 26.9 0.3 1e-05 25.8 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER27051.1 - 1.9e-05 24.8 0.2 4.4e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EER27051.1 - 0.00017 20.5 2.4 0.0014 17.5 0.9 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EER27051.1 - 0.00019 20.0 0.5 0.0003 19.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EER27051.1 - 0.00037 19.4 0.3 0.00057 18.8 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EER27051.1 - 0.00079 18.3 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EER27051.1 - 0.0014 17.7 0.4 0.0023 17.0 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EER27051.1 - 0.0019 18.1 0.4 0.0065 16.3 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER27051.1 - 0.0025 16.9 0.2 0.0039 16.3 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EER27051.1 - 0.025 13.5 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EER27051.1 - 0.028 14.0 0.3 0.067 12.8 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EER27051.1 - 0.055 12.5 0.3 0.22 10.5 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EER27051.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EER27051.1 - 0.2 11.4 1.2 4.2 7.1 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_10 PF13460.1 EER27051.1 - 0.23 11.4 0.6 0.51 10.3 0.4 1.6 1 0 0 1 1 1 0 NADH(P)-binding Homeobox PF00046.24 EER27052.1 - 7.6e-14 51.0 2.0 7.6e-14 51.0 1.4 2.2 2 0 0 2 2 2 1 Homeobox domain NmrA PF05368.8 EER27053.1 - 3.3e-08 33.0 0.0 3.8e-07 29.5 0.0 2.2 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EER27053.1 - 3.5e-06 27.1 0.0 1.9e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding F-box-like PF12937.2 EER27054.1 - 0.0002 21.0 0.0 0.0008 19.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EER27054.1 - 0.016 14.8 0.4 0.21 11.2 0.0 2.9 3 0 0 3 3 3 0 F-box domain Methyltransf_11 PF08241.7 EER27056.1 - 2.9e-21 75.7 0.1 3.3e-21 75.5 0.1 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER27056.1 - 6.5e-16 58.4 0.0 7.7e-16 58.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER27056.1 - 7.4e-16 58.0 0.0 8.6e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27056.1 - 1.8e-13 50.7 0.1 2.2e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER27056.1 - 2.1e-13 50.3 1.2 2.9e-13 49.8 0.8 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER27056.1 - 5.7e-13 49.1 0.3 6.7e-13 48.8 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EER27056.1 - 3e-12 46.1 0.0 3.6e-12 45.9 0.0 1.0 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EER27056.1 - 1.9e-11 44.5 0.1 2.2e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER27056.1 - 8.3e-10 38.3 0.1 1.2e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EER27056.1 - 4.3e-08 32.5 0.0 5.2e-08 32.2 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EER27056.1 - 1e-06 28.2 0.0 1.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.13 EER27056.1 - 3.9e-05 23.2 0.0 4.7e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 EER27056.1 - 0.00018 21.0 0.0 0.00018 21.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EER27056.1 - 0.00024 20.1 0.0 0.001 18.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_15 PF09445.5 EER27056.1 - 0.00044 19.8 0.1 0.00053 19.5 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EER27056.1 - 0.00071 18.7 0.1 0.00089 18.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EER27056.1 - 0.00095 18.8 0.1 0.001 18.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EER27056.1 - 0.001 17.8 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.7 EER27056.1 - 0.0011 18.3 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase NodS PF05401.6 EER27056.1 - 0.0013 18.2 0.0 0.0015 18.0 0.0 1.0 1 0 0 1 1 1 1 Nodulation protein S (NodS) TehB PF03848.9 EER27056.1 - 0.0022 17.1 0.0 0.0023 17.1 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 EER27056.1 - 0.0093 16.7 0.4 0.013 16.3 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EER27056.1 - 0.047 13.0 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF633 PF04816.7 EER27056.1 - 0.072 12.4 0.4 0.087 12.1 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF633) TPMT PF05724.6 EER27056.1 - 0.082 12.3 0.0 0.082 12.3 0.0 1.3 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Ank_2 PF12796.2 EER27057.1 - 2.3e-31 107.9 0.8 2.1e-18 66.4 0.0 3.6 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 EER27057.1 - 2.3e-29 99.7 0.2 3.9e-11 42.1 0.0 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 EER27057.1 - 3.6e-22 76.2 0.3 4.4e-07 29.5 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EER27057.1 - 8.4e-19 67.1 0.4 1.1e-08 34.9 0.0 4.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EER27057.1 - 2.4e-18 66.1 0.8 4.8e-10 39.6 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EER27057.1 - 1.7e-11 43.5 0.1 3.2e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EER27057.1 - 1.2e-09 38.0 0.1 2.3e-09 37.1 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EER27057.1 - 0.0021 18.2 0.3 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EER27057.1 - 0.11 11.4 0.0 0.61 8.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EER27057.1 - 0.11 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DSPn PF14671.1 EER27058.1 - 2.4e-41 141.0 0.0 4e-38 130.5 0.0 3.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EER27058.1 - 1.5e-16 60.1 0.0 4.5e-16 58.6 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EER27058.1 - 7.7e-06 25.4 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EER27058.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EER27058.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Pcc1 PF09341.5 EER27059.1 - 3.2e-13 49.5 0.0 3.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 HATPase_c PF02518.21 EER27060.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EER27060.1 - 3e-06 27.2 0.0 1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain Translin PF01997.11 EER27061.1 - 7.3e-53 179.1 0.1 8.5e-53 178.9 0.1 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 EER27061.1 - 0.011 15.4 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 GMP synthase C terminal domain HR1 PF02185.11 EER27061.1 - 0.037 13.7 0.3 0.073 12.8 0.2 1.5 1 0 0 1 1 1 0 Hr1 repeat Atg14 PF10186.4 EER27061.1 - 0.042 12.7 0.9 0.078 11.9 0.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin-6_N PF09177.6 EER27061.1 - 0.058 13.8 0.4 0.16 12.4 0.2 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Herpes_UL25 PF01499.11 EER27061.1 - 0.06 11.6 0.1 0.088 11.0 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family GSHPx PF00255.14 EER27062.1 - 1.8e-37 126.9 0.0 2.3e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EER27062.1 - 0.00076 19.1 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EER27062.1 - 0.0093 15.5 0.1 0.015 14.8 0.1 1.6 1 1 0 1 1 1 1 Redoxin SCO1-SenC PF02630.9 EER27062.1 - 0.096 12.2 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 SCO1/SenC Ribosomal_L22e PF01776.12 EER27063.1 - 3.1e-51 172.0 0.2 3.5e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family RNase_T PF00929.19 EER27064.1 - 5.5e-08 33.2 0.0 5.3e-07 30.0 0.0 2.1 1 1 0 1 1 1 1 Exonuclease Peptidase_S8 PF00082.17 EER27065.1 - 6.1e-41 140.4 6.6 6.1e-41 140.4 4.6 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EER27065.1 - 4.4e-13 49.6 0.0 8e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Hydrolase_6 PF13344.1 EER27066.1 - 5.3e-23 80.8 0.0 9.5e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER27066.1 - 2.5e-10 39.8 0.0 4.6e-09 35.8 0.0 2.9 2 2 1 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EER27066.1 - 0.0025 18.2 0.0 0.03 14.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EER27066.1 - 0.014 15.6 0.0 2.6 8.2 0.0 2.5 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CFEM PF05730.6 EER27067.1 - 0.00085 19.0 4.5 0.0018 18.0 3.1 1.5 1 0 0 1 1 1 1 CFEM domain Pmp3 PF01679.12 EER27068.1 - 1.5e-26 91.8 6.2 1.6e-26 91.7 4.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EER27068.1 - 5.4 6.7 6.2 0.72 9.5 1.1 1.8 2 0 0 2 2 2 0 Conserved TM helix MMR_HSR1_C PF08438.5 EER27070.1 - 1.2e-31 109.1 0.0 2.3e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EER27070.1 - 3.5e-11 43.0 0.0 1.1e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EER27070.1 - 0.016 15.1 0.0 0.047 13.6 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 EER27070.1 - 0.037 13.5 0.0 6.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein VirB8 PF04335.8 EER27070.1 - 0.063 12.8 0.0 0.53 9.8 0.0 2.1 2 0 0 2 2 2 0 VirB8 protein AIG1 PF04548.11 EER27070.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.22 EER27070.1 - 0.093 13.0 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 ABC transporter SET PF00856.23 EER27071.1 - 0.018 15.3 0.0 0.029 14.6 0.0 1.6 1 1 0 1 1 1 0 SET domain Fungal_trans PF04082.13 EER27072.1 - 6.2e-32 110.4 1.5 1e-31 109.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER27072.1 - 1.7e-08 34.2 14.9 3.6e-08 33.1 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Transketolase_N PF00456.16 EER27073.1 - 3.2e-150 499.5 0.0 4.5e-150 499.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EER27073.1 - 1.5e-45 154.8 0.0 2.4e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EER27073.1 - 1.2e-13 51.1 0.0 2.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EER27073.1 - 1.6e-07 30.5 0.0 0.00032 19.7 0.0 2.3 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EER27073.1 - 0.0021 16.8 0.1 0.0032 16.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Beta_elim_lyase PF01212.16 EER27073.1 - 0.032 13.3 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Spermine_synth PF01564.12 EER27074.1 - 4.9e-94 313.8 0.0 6.2e-94 313.5 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EER27074.1 - 0.00038 20.0 0.0 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER27074.1 - 0.0017 18.8 0.0 0.0032 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27074.1 - 0.0032 17.9 0.1 0.0084 16.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EER27074.1 - 0.0061 15.7 0.1 0.015 14.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EER27074.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_30 PF05430.6 EER27074.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase bZIP_1 PF00170.16 EER27075.1 - 4e-06 26.6 18.1 8.7e-05 22.4 8.2 2.4 1 1 1 2 2 2 2 bZIP transcription factor PspA_IM30 PF04012.7 EER27075.1 - 0.0012 18.2 1.8 0.0017 17.7 1.2 1.3 1 0 0 1 1 1 1 PspA/IM30 family TSC22 PF01166.13 EER27075.1 - 0.0048 16.8 2.3 0.0061 16.5 0.3 2.0 1 1 1 2 2 2 1 TSC-22/dip/bun family Nup54 PF13874.1 EER27075.1 - 0.0067 16.0 7.8 0.019 14.6 4.9 2.3 1 1 1 2 2 2 1 Nucleoporin complex subunit 54 Transcrip_act PF04949.8 EER27075.1 - 0.0077 15.8 1.2 0.011 15.3 0.8 1.3 1 0 0 1 1 1 1 Transcriptional activator Transposase_22 PF02994.9 EER27075.1 - 0.013 14.0 1.0 0.017 13.6 0.7 1.1 1 0 0 1 1 1 0 L1 transposable element IncA PF04156.9 EER27075.1 - 0.013 15.0 5.2 0.017 14.6 3.6 1.2 1 0 0 1 1 1 0 IncA protein FAM92 PF06730.6 EER27075.1 - 0.017 14.4 0.6 0.024 13.9 0.4 1.2 1 0 0 1 1 1 0 FAM92 protein TMF_TATA_bd PF12325.3 EER27075.1 - 0.017 14.8 2.7 0.027 14.1 1.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_Maf PF03131.12 EER27075.1 - 0.029 14.6 9.9 0.064 13.5 6.9 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6 PF04111.7 EER27075.1 - 0.041 12.9 5.6 0.055 12.5 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Vac_Fusion PF02346.11 EER27075.1 - 0.05 13.0 1.0 0.1 12.0 0.7 1.6 1 0 0 1 1 1 0 Chordopoxvirus fusion protein DUF848 PF05852.6 EER27075.1 - 0.069 12.9 2.3 0.099 12.4 1.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2400 PF09674.5 EER27075.1 - 0.076 12.7 1.5 0.11 12.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) bZIP_2 PF07716.10 EER27075.1 - 0.11 12.3 18.9 0.3 10.9 9.6 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DUF4404 PF14357.1 EER27075.1 - 0.12 12.7 1.7 0.18 12.2 0.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) DUF4254 PF14063.1 EER27075.1 - 0.15 11.6 4.7 0.26 10.8 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4254) DUF342 PF03961.8 EER27075.1 - 0.24 9.7 1.7 0.3 9.4 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EAP30 PF04157.11 EER27075.1 - 0.25 10.4 2.8 0.34 10.0 1.9 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family FimP PF09766.4 EER27075.1 - 0.34 9.9 5.5 0.61 9.0 2.9 1.7 1 1 1 2 2 2 0 Fms-interacting protein Fmp27_WPPW PF10359.4 EER27075.1 - 0.34 9.2 5.8 0.51 8.6 4.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DivIC PF04977.10 EER27075.1 - 0.54 9.7 3.2 0.54 9.7 0.6 1.9 1 1 1 2 2 2 0 Septum formation initiator Jnk-SapK_ap_N PF09744.4 EER27075.1 - 0.84 9.6 8.1 1.2 9.1 5.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF972 PF06156.8 EER27075.1 - 1 9.7 4.7 1 9.7 2.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EER27075.1 - 1.1 9.7 5.3 3.3 8.2 3.6 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) V_ATPase_I PF01496.14 EER27075.1 - 1.3 6.7 3.5 1.7 6.4 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2937 PF11157.3 EER27075.1 - 2.6 7.3 4.7 5.8 6.2 2.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) GvpL_GvpF PF06386.6 EER27075.1 - 6.3 6.2 8.1 12 5.3 5.6 1.5 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Spt5_N PF11942.3 EER27075.1 - 6.5 7.4 8.4 11 6.7 5.8 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal G-alpha PF00503.15 EER27076.1 - 5.3e-115 384.2 0.0 6.3e-115 383.9 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EER27076.1 - 5.3e-14 51.8 0.7 2.3e-09 36.7 0.0 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER27076.1 - 1.7e-06 27.3 0.0 0.014 14.4 0.0 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EER27076.1 - 0.0033 17.9 0.1 0.36 11.3 0.1 3.0 2 2 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EER27076.1 - 0.0085 16.0 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EER27076.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EER27076.1 - 0.076 12.4 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF1713 PF08213.6 EER27077.1 - 8.9e-13 47.6 18.5 8.9e-13 47.6 12.8 2.2 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EER27077.1 - 0.02 14.8 0.1 0.082 12.8 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial protein Pet20 PilP PF04351.8 EER27077.1 - 6.5 6.6 7.3 0.52 10.1 0.2 2.3 2 1 0 2 2 2 0 Pilus assembly protein, PilP ATP-synt_C PF00137.16 EER27078.1 - 1.2e-30 105.1 25.3 1.3e-17 63.4 8.5 2.3 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L7Ae PF01248.21 EER27079.1 - 1.1e-17 63.3 7.3 1.1e-17 63.2 0.7 3.0 2 1 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family UcrQ PF02939.11 EER27080.1 - 2.6e-28 97.6 0.2 3.1e-28 97.4 0.1 1.0 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 EER27081.1 - 7e-25 87.9 6.3 7e-25 87.9 4.4 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EER27081.1 - 0.015 14.6 0.8 0.028 13.8 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF3115 PF11312.3 EER27083.1 - 1.3e-93 313.3 0.0 2e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Lipase_GDSL_2 PF13472.1 EER27083.1 - 0.097 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF202 PF02656.10 EER27085.1 - 1.2e-25 89.5 0.2 1.2e-25 89.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.10 EER27086.1 - 2.8e-110 368.1 0.0 3.3e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ank_2 PF12796.2 EER27087.1 - 4.6e-75 248.0 12.8 1.4e-14 54.1 0.2 7.4 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EER27087.1 - 2.9e-54 178.2 18.5 2.6e-06 26.9 0.0 13.4 12 1 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.1 EER27087.1 - 5e-45 146.9 8.9 5.8e-05 22.9 0.0 13.9 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.1 EER27087.1 - 1.7e-41 139.3 22.6 3.8e-08 33.3 0.1 10.6 7 2 4 11 11 11 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EER27087.1 - 1.8e-41 139.7 11.8 1.9e-05 25.0 0.0 10.2 8 2 3 11 11 11 8 Ankyrin repeats (many copies) Fer2_3 PF13085.1 EER27088.1 - 3.1e-32 110.6 0.0 5e-32 109.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EER27088.1 - 1e-09 38.5 6.3 1e-09 38.5 4.4 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EER27088.1 - 2e-09 37.3 5.0 2e-09 37.3 3.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EER27088.1 - 4.9e-05 23.5 4.0 0.034 14.4 0.3 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EER27088.1 - 9.8e-05 22.0 4.7 9.8e-05 22.0 3.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EER27088.1 - 0.00043 20.6 2.8 0.00043 20.6 1.9 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 EER27088.1 - 0.006 16.2 0.3 0.006 16.2 0.2 2.5 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EER27088.1 - 0.015 15.7 7.2 0.015 15.7 5.0 2.5 2 2 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 EER27088.1 - 0.26 11.8 5.0 0.86 10.2 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain F_bP_aldolase PF01116.15 EER27089.1 - 5.9e-84 281.5 0.0 6.6e-84 281.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Acetyltransf_1 PF00583.19 EER27090.1 - 7e-09 35.6 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EER27090.1 - 1.7e-05 24.8 0.1 9.5e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER27090.1 - 0.0031 17.6 0.0 0.0054 16.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain RTA1 PF04479.8 EER27091.1 - 3.9e-54 183.5 1.0 5.3e-54 183.0 0.7 1.1 1 0 0 1 1 1 1 RTA1 like protein OAD_gamma PF04277.8 EER27091.1 - 0.09 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF4131 PF13567.1 EER27091.1 - 8.9 5.6 8.0 0.95 8.8 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Evr1_Alr PF04777.8 EER27092.1 - 9.9e-29 99.1 0.6 1.4e-28 98.6 0.4 1.2 1 0 0 1 1 1 1 Erv1 / Alr family DUF4553 PF15090.1 EER27092.1 - 0.11 11.4 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4553) zf-LYAR PF08790.6 EER27093.1 - 1.1e-13 50.6 3.7 1.1e-13 50.6 2.5 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger CAP_N PF01213.14 EER27093.1 - 4.8 6.3 8.2 0.43 9.8 2.3 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal R3H PF01424.17 EER27094.1 - 2.7e-10 39.8 0.0 6.1e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EER27094.1 - 7.1e-06 25.8 191.1 0.0061 16.4 11.7 14.3 11 5 1 12 12 12 8 NF-X1 type zinc finger SIMPL PF04402.9 EER27094.1 - 0.98 9.2 1.9 1.7 8.4 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) G_glu_transpept PF01019.16 EER27095.1 - 2.3e-165 550.9 0.0 2.6e-165 550.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HhH-GPD PF00730.20 EER27096.1 - 2.7e-07 30.8 0.0 4.8e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Git3 PF11710.3 EER27098.1 - 2.1e-29 102.5 8.4 3.8e-29 101.6 5.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EER27098.1 - 2.3e-09 36.8 0.0 6e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EER27098.1 - 9e-06 25.0 8.2 1.3e-05 24.4 5.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EER27098.1 - 0.0002 20.3 4.7 0.0002 20.3 2.4 1.4 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor OapA_N PF08525.6 EER27098.1 - 0.026 14.2 0.0 0.11 12.2 0.0 2.2 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif MFS_1 PF07690.11 EER27099.1 - 5.6e-08 31.8 47.6 4.1e-05 22.4 11.0 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EER27099.1 - 0.004 17.0 0.9 0.004 17.0 0.6 2.4 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 TRI12 PF06609.8 EER27099.1 - 0.03 12.5 15.5 0.0064 14.7 4.5 2.8 1 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EER27100.1 - 1.6e-50 171.7 32.2 1.6e-50 171.7 22.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER27100.1 - 2.1e-11 43.1 9.6 2.1e-11 43.1 6.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter CAAD PF14159.1 EER27100.1 - 2.5 7.8 6.8 6.6 6.4 1.9 3.4 2 1 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Methyltransf_23 PF13489.1 EER27101.1 - 7.8e-09 35.4 0.0 1.7e-07 31.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER27101.1 - 0.0007 19.2 0.0 0.0091 15.5 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27101.1 - 0.06 13.8 0.0 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EER27101.1 - 0.097 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Amidase PF01425.16 EER27102.1 - 1.2e-68 232.0 0.1 3.2e-64 217.4 0.0 2.0 2 0 0 2 2 2 2 Amidase PTCB-BRCT PF12738.2 EER27103.1 - 7.7e-15 54.5 0.0 1.8e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EER27103.1 - 1.9e-09 37.5 0.0 4.3e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EER27103.1 - 0.0041 17.2 0.0 0.0099 15.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EER27103.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) ERCC4 PF02732.10 EER27104.1 - 9.4e-23 80.5 0.0 4.4e-22 78.3 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain eIF-1a PF01176.14 EER27105.1 - 1.2e-28 98.2 0.1 1.7e-28 97.7 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 WH1 PF00568.18 EER27106.1 - 3.7e-29 100.6 0.0 5.4e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EER27106.1 - 0.0059 16.1 0.3 0.0059 16.1 0.2 2.0 2 0 0 2 2 2 1 WH2 motif CorA PF01544.13 EER27107.1 - 3.8e-08 32.7 0.1 5.7e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein RHH_3 PF12651.2 EER27107.1 - 0.33 10.7 2.3 0.45 10.2 0.2 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix domain SEN1_N PF12726.2 EER27109.1 - 2e-214 713.8 0.5 3.1e-214 713.1 0.3 1.3 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EER27109.1 - 1.1e-69 234.5 1.4 1.1e-69 234.5 1.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EER27109.1 - 6.9e-62 208.3 0.0 1.3e-61 207.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER27109.1 - 1.2e-10 41.0 1.8 1.2e-10 40.9 0.2 1.8 2 0 0 2 2 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EER27109.1 - 4.5e-09 36.1 0.0 0.0054 16.2 0.0 3.7 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EER27109.1 - 1.3e-08 34.6 0.3 2.3e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EER27109.1 - 2.9e-07 30.1 4.7 3.1e-07 30.0 0.2 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain zf-CCHC PF00098.18 EER27109.1 - 0.00024 20.8 2.3 0.00024 20.8 1.6 3.3 3 0 0 3 3 3 1 Zinc knuckle DEAD PF00270.24 EER27109.1 - 0.00043 19.8 0.4 0.004 16.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EER27109.1 - 0.0011 18.8 1.5 0.0019 18.0 0.1 2.1 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EER27109.1 - 0.04 13.3 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EER27109.1 - 0.043 13.9 0.1 2.4 8.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 EER27109.1 - 0.07 13.4 4.1 0.089 13.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EER27109.1 - 0.17 11.4 0.1 0.4 10.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CCHC_4 PF14392.1 EER27109.1 - 4.6 6.9 15.3 11 5.7 0.3 3.8 3 0 0 3 3 3 0 Zinc knuckle E1-E2_ATPase PF00122.15 EER27110.1 - 3.2e-14 52.5 0.0 7.9e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EER27110.1 - 6.6e-12 45.9 0.0 1.4e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER27110.1 - 9.2e-12 44.7 0.0 2.2e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EER27110.1 - 2.6e-10 41.0 0.3 1.3e-08 35.5 0.2 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER27110.1 - 0.025 14.1 0.5 0.052 13.1 0.3 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.13 EER27112.1 - 1.8e-51 174.2 17.8 3.9e-51 173.1 12.4 1.5 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Mg_trans_NIPA PF05653.9 EER27113.1 - 3.5e-13 49.1 4.3 8.6e-10 38.0 0.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EER27113.1 - 0.0015 18.5 1.9 0.0015 18.5 1.3 2.7 3 0 0 3 3 3 2 EamA-like transporter family TMEM61 PF15105.1 EER27113.1 - 0.14 11.6 1.5 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 TMEM61 protein family IncA PF04156.9 EER27113.1 - 0.41 10.2 4.4 0.88 9.1 0.0 2.5 2 0 0 2 2 2 0 IncA protein EmrE PF13536.1 EER27113.1 - 0.85 9.8 14.7 2 8.6 0.3 3.3 2 1 1 3 3 3 0 Multidrug resistance efflux transporter SRF-TF PF00319.13 EER27114.1 - 1.5e-23 81.7 0.2 2.1e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Abhydrolase_2 PF02230.11 EER27115.1 - 1.3e-27 96.6 0.0 2e-18 66.6 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EER27115.1 - 5.4e-06 26.4 0.0 3.8e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27115.1 - 1.4e-05 24.8 0.0 2.6e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER27115.1 - 0.00018 20.8 0.1 0.00047 19.4 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EER27115.1 - 0.048 13.0 0.0 0.16 11.3 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 EER27115.1 - 0.068 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Secretory lipase BAAT_C PF08840.6 EER27115.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Sulfatase PF00884.18 EER27118.1 - 7.6e-62 209.2 0.6 9.8e-62 208.8 0.4 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EER27118.1 - 0.00061 19.2 2.6 0.005 16.2 1.8 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Tetraspannin PF00335.15 EER27119.1 - 5.7e-07 29.0 1.3 1e-06 28.2 0.9 1.3 1 0 0 1 1 1 1 Tetraspanin family SUR7 PF06687.7 EER27119.1 - 0.18 11.3 5.1 0.14 11.7 2.4 1.7 1 1 1 2 2 2 0 SUR7/PalI family SdpI PF13630.1 EER27119.1 - 5.8 6.7 12.0 1.6 8.4 3.5 3.0 3 2 1 4 4 4 0 SdpI/YhfL protein family Acetyltransf_1 PF00583.19 EER27120.1 - 8.6e-06 25.7 0.7 0.039 13.9 0.0 2.7 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER27120.1 - 0.03 14.4 0.0 0.2 11.8 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.6 EER27121.1 - 2.2e-07 30.0 1.7 2.1e-06 26.9 0.1 2.6 3 0 0 3 3 3 1 Sgf11 (transcriptional regulation protein) NAD_binding_6 PF08030.7 EER27122.1 - 7.3e-20 71.4 0.0 1.3e-19 70.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EER27122.1 - 1.2e-17 64.1 9.5 2.2e-17 63.3 5.7 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EER27122.1 - 3.2e-14 52.6 0.0 8.4e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EER27122.1 - 0.003 18.0 0.0 4.7 7.8 0.0 2.9 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EER27122.1 - 0.12 12.4 10.0 0.16 12.1 1.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) RNase_PH PF01138.16 EER27123.1 - 9.7e-21 74.4 0.1 3.6e-20 72.6 0.1 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_A22B PF04258.8 EER27124.1 - 2.7e-53 181.3 0.0 1.1e-52 179.3 0.0 1.8 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EER27124.1 - 0.00039 19.6 9.5 0.00052 19.2 3.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) Pro_isomerase PF00160.16 EER27125.1 - 2.4e-53 180.5 0.0 2.8e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GDI PF00996.13 EER27126.1 - 1.2e-18 66.6 0.0 1.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF1690 PF07956.6 EER27127.1 - 1.6e-30 105.9 10.5 3.9e-15 56.0 0.4 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) FliT PF05400.8 EER27127.1 - 0.043 14.2 2.2 0.043 14.2 1.5 2.3 2 1 0 2 2 2 0 Flagellar protein FliT Terminase_2 PF03592.11 EER27127.1 - 0.084 13.1 2.8 2.1 8.6 0.3 2.1 2 0 0 2 2 2 0 Terminase small subunit HrpA_pilin PF09589.5 EER27127.1 - 0.15 12.5 8.1 1.9 8.9 0.9 2.2 1 1 1 2 2 2 0 HrpA pilus formation protein Phasin PF05597.6 EER27127.1 - 0.42 10.3 6.1 0.1 12.3 0.5 2.2 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) PolyA_pol PF01743.15 EER27127.1 - 0.92 9.7 4.4 1.5 9.0 1.7 2.1 1 1 1 2 2 2 0 Poly A polymerase head domain POP1 PF06978.6 EER27128.1 - 1.1e-65 220.8 11.9 1.1e-65 220.8 8.3 2.1 3 0 0 3 3 3 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EER27128.1 - 6.9e-31 105.9 1.0 1.8e-30 104.5 0.7 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain Redoxin PF08534.5 EER27129.1 - 3.5e-38 130.4 0.0 4e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EER27129.1 - 8.9e-12 44.7 0.0 1.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Hexokinase_2 PF03727.11 EER27130.1 - 1.1e-65 221.2 0.0 1.5e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EER27130.1 - 5.5e-64 215.2 0.0 9e-64 214.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Yip1 PF04893.12 EER27131.1 - 0.052 13.0 5.9 0.091 12.2 4.1 1.3 1 0 0 1 1 1 0 Yip1 domain DUF2975 PF11188.3 EER27131.1 - 1.8 8.3 9.2 0.82 9.3 4.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) zf-C2HC5 PF06221.8 EER27132.1 - 5.2e-23 80.5 5.0 8.4e-23 79.8 3.5 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FAD_syn PF06574.7 EER27132.1 - 0.069 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Imm45 PF15603.1 EER27132.1 - 0.13 12.4 0.7 1.2 9.2 0.0 2.8 3 1 0 3 3 3 0 Immunity protein 45 DUF604 PF04646.7 EER27133.1 - 2e-05 23.9 0.0 3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EER27133.1 - 0.00011 21.4 0.0 0.00038 19.7 0.0 1.8 2 0 0 2 2 2 1 Fringe-like APH PF01636.18 EER27134.1 - 2e-12 47.3 0.0 1.3e-11 44.6 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER27134.1 - 3.1e-06 26.9 0.0 5.6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DAO PF01266.19 EER27135.1 - 3.4e-15 55.8 0.0 8.1e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Fasciclin PF02469.17 EER27136.1 - 7.7e-42 142.3 0.1 4.9e-25 88.0 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Pkinase PF00069.20 EER27137.1 - 2.6e-69 233.2 0.0 4.3e-69 232.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27137.1 - 9.8e-32 110.0 0.0 1.1e-30 106.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER27137.1 - 0.0025 17.5 0.0 0.051 13.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Alpha-amylase PF00128.19 EER27137.1 - 0.0043 16.5 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Kdo PF06293.9 EER27137.1 - 0.0057 15.7 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EER27137.1 - 0.0064 15.4 0.0 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EER27137.1 - 0.03 13.9 0.0 0.073 12.6 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Zn_clus PF00172.13 EER27138.1 - 8.6e-09 35.1 7.4 1.3e-08 34.6 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2461 PF09365.5 EER27140.1 - 7.9e-41 139.7 4.7 6e-40 136.9 0.8 2.9 2 1 0 2 2 2 1 Conserved hypothetical protein (DUF2461) TYW3 PF02676.9 EER27141.1 - 1.2e-68 230.3 0.0 1.4e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 PAM2 PF07145.10 EER27142.1 - 0.0037 16.6 0.2 0.016 14.6 0.1 2.2 1 0 0 1 1 1 1 Ataxin-2 C-terminal region RRM_6 PF14259.1 EER27142.1 - 0.045 13.7 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 EER27143.1 - 7.8e-76 253.1 3.5 8.6e-76 253.0 2.5 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 EER27144.1 - 8.3e-55 185.7 0.0 1e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER27144.1 - 5.8e-19 68.6 1.1 1.9e-18 66.9 0.8 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EER27144.1 - 3e-10 39.3 0.0 7.2e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EER27144.1 - 0.1 12.8 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 Ubiquitin-like domain 4HBT PF03061.17 EER27145.1 - 2.3e-10 40.4 0.0 3.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EER27145.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) TRI12 PF06609.8 EER27146.1 - 1.9e-13 49.4 6.9 2.3e-13 49.2 4.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EER27146.1 - 2.9e-05 22.9 15.2 8.1e-05 21.4 8.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER27146.1 - 0.78 8.2 17.6 0.025 13.1 7.5 1.7 2 0 0 2 2 2 0 Sugar (and other) transporter DUF2207 PF09972.4 EER27146.1 - 6.5 5.2 11.6 0.085 11.4 2.3 2.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) WD40 PF00400.27 EER27147.1 - 1.8e-11 43.4 17.7 4.9e-05 23.0 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat RWD PF05773.17 EER27147.1 - 0.00039 20.2 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 RWD domain Stc1 PF12898.2 EER27147.1 - 0.0041 17.1 1.6 0.0041 17.1 1.1 2.3 1 1 1 2 2 2 1 Stc1 domain UQ_con PF00179.21 EER27148.1 - 9.9e-47 157.8 0.0 1.1e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER27148.1 - 3.8e-05 23.4 0.0 4.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EER27148.1 - 0.012 15.3 0.1 0.023 14.3 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EER27148.1 - 0.032 14.1 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain Ribosomal_L24e PF01246.15 EER27149.1 - 2.6e-31 107.2 0.4 2.6e-31 107.2 0.2 1.9 2 1 0 2 2 2 1 Ribosomal protein L24e Ribosomal_S30 PF04758.9 EER27150.1 - 9.7e-30 102.1 7.5 1e-29 102.0 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Acetyltransf_7 PF13508.1 EER27151.1 - 1.2e-10 41.3 0.2 1.6e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER27151.1 - 5.6e-10 39.1 0.1 8.3e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EER27151.1 - 9.3e-05 22.6 0.0 0.00012 22.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER27151.1 - 0.016 15.0 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER27151.1 - 0.023 14.6 0.1 0.035 14.0 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER27151.1 - 0.085 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lyase_1 PF00206.15 EER27152.1 - 2.9e-111 371.6 0.0 3.9e-111 371.2 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EER27152.1 - 9.1e-23 80.0 0.0 2.7e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus AKNA PF12443.3 EER27152.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AT-hook-containing transcription factor ADH_N PF08240.7 EER27152.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Abhydrolase_3 PF07859.8 EER27153.1 - 9e-61 205.1 0.1 1.2e-60 204.7 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EER27153.1 - 1.8e-08 33.9 0.0 8.4e-07 28.4 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EER27153.1 - 1.2e-06 28.5 0.5 1.9e-06 27.9 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EER27153.1 - 0.0002 20.2 1.3 0.00057 18.7 0.9 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EER27153.1 - 0.0014 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EER27153.1 - 0.0036 16.5 0.0 0.0081 15.4 0.0 1.6 1 0 0 1 1 1 1 Esterase PHB depolymerase FMO-like PF00743.14 EER27154.1 - 5.6e-98 328.4 0.0 6.8e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EER27154.1 - 2.7e-21 76.5 0.0 7.3e-21 75.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EER27154.1 - 2.7e-08 33.1 0.0 1.4e-06 27.4 0.0 2.8 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EER27154.1 - 1.6e-07 31.2 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER27154.1 - 5.4e-06 26.4 0.0 8.5e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER27154.1 - 1.1e-05 25.2 0.0 0.0045 16.7 0.0 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EER27154.1 - 1.2e-05 24.3 0.0 0.0047 15.8 0.0 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EER27154.1 - 0.005 17.2 0.1 2.6 8.5 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EER27154.1 - 0.11 12.8 0.6 21 5.6 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Amino_oxidase PF01593.19 EER27154.1 - 0.13 11.3 0.0 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EER27154.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EER27154.1 - 0.17 10.9 0.1 0.35 9.9 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Cyclin PF08613.6 EER27155.1 - 1.9e-13 51.0 0.0 4e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EER27155.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Pyrid_oxidase_2 PF13883.1 EER27156.1 - 9.3e-34 116.6 0.0 1.3e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Ipi1_N PF12333.3 EER27157.1 - 8.1e-28 96.3 0.0 3.2e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Robl_LC7 PF03259.12 EER27158.1 - 6.3e-05 22.4 0.2 0.008 15.7 0.0 3.0 3 0 0 3 3 3 1 Roadblock/LC7 domain Hydantoinase_A PF01968.13 EER27159.1 - 0.039 13.0 0.1 0.045 12.8 0.0 1.0 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF4230 PF14014.1 EER27159.1 - 0.061 13.1 0.1 0.061 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DUF1824 PF08854.5 EER27159.1 - 0.063 12.9 0.1 0.073 12.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) DUF883 PF05957.8 EER27159.1 - 0.065 13.6 0.7 0.077 13.3 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EER27159.1 - 0.098 13.0 1.8 0.12 12.7 1.2 1.1 1 0 0 1 1 1 0 YtxH-like protein ATP-synt_B PF00430.13 EER27159.1 - 0.23 11.2 1.8 0.26 11.0 1.3 1.0 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Tubulin PF00091.20 EER27160.1 - 2e-52 178.1 0.0 2.4e-28 99.4 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EER27160.1 - 3e-44 150.0 0.6 4.9e-44 149.3 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain HisG PF01634.13 EER27160.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 ATP phosphoribosyltransferase Abhydrolase_3 PF07859.8 EER27161.1 - 6.6e-25 87.9 0.0 9.3e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EER27161.1 - 3.4e-22 78.6 0.0 4.5e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EER27161.1 - 2.6e-05 24.0 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER27161.1 - 0.00079 18.7 0.0 0.0028 16.9 0.0 1.9 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EER27161.1 - 0.0066 16.3 0.0 0.0096 15.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EER27161.1 - 0.076 11.7 0.5 7.5 5.1 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family DUF2974 PF11187.3 EER27161.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PMI_typeI PF01238.16 EER27162.1 - 8.1e-145 482.4 0.0 9.4e-145 482.2 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EER27162.1 - 0.013 15.0 0.0 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 Cupin domain AraC_binding PF02311.14 EER27162.1 - 0.013 15.1 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain DUF1325 PF07039.6 EER27163.1 - 1.5e-30 105.4 0.0 2.5e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain AMP-binding PF00501.23 EER27164.1 - 7.6e-43 146.4 0.0 1e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER27164.1 - 6.5e-08 33.4 0.3 6.4e-07 30.2 0.1 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GTP_cyclohydro2 PF00925.15 EER27165.1 - 3.3e-57 192.4 0.0 1.1e-51 174.4 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II PT PF04886.7 EER27165.1 - 0.017 14.4 3.1 0.048 12.9 2.1 1.8 1 0 0 1 1 1 0 PT repeat Methyltransf_31 PF13847.1 EER27166.1 - 1.3e-15 57.2 0.0 2.5e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER27166.1 - 2.9e-15 56.3 0.1 3.7e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER27166.1 - 3.3e-13 49.9 0.0 9.7e-13 48.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27166.1 - 3.7e-13 49.7 0.0 1.6e-12 47.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER27166.1 - 6.8e-12 45.9 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER27166.1 - 1.4e-09 38.2 0.0 3.4e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER27166.1 - 2.9e-07 29.8 0.0 5e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EER27166.1 - 3.5e-05 23.7 0.0 0.00014 21.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EER27166.1 - 4e-05 23.3 0.0 5.2e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EER27166.1 - 0.0044 15.9 0.0 0.011 14.6 0.0 1.6 2 0 0 2 2 2 1 DREV methyltransferase MTS PF05175.9 EER27166.1 - 0.0093 15.3 0.0 0.019 14.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 EER27166.1 - 0.02 13.6 0.0 0.036 12.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) tRNA_U5-meth_tr PF05958.6 EER27166.1 - 0.087 11.4 0.0 0.12 11.0 0.0 1.4 1 1 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NNMT_PNMT_TEMT PF01234.12 EER27166.1 - 0.11 11.4 0.2 1.2 8.0 0.0 2.2 2 1 0 2 2 2 0 NNMT/PNMT/TEMT family RrnaAD PF00398.15 EER27166.1 - 0.15 11.0 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF3425 PF11905.3 EER27167.1 - 9e-36 122.7 5.0 2e-35 121.6 3.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EER27167.1 - 0.00048 20.0 10.6 0.0012 18.8 7.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EER27167.1 - 7.1 6.5 13.3 4.8 7.0 7.2 2.1 1 1 1 2 2 2 0 Basic region leucine zipper Actin PF00022.14 EER27168.1 - 1.7e-119 398.7 0.0 1.9e-119 398.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EER27168.1 - 0.024 13.2 0.0 0.15 10.6 0.0 2.2 1 1 0 1 1 1 0 MreB/Mbl protein EamA PF00892.15 EER27169.1 - 1.3e-09 38.1 27.2 7.7e-06 25.9 9.4 2.5 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EER27169.1 - 0.0002 21.5 0.4 0.0002 21.5 0.3 2.8 3 0 0 3 3 3 2 Multidrug resistance efflux transporter PgaD PF13994.1 EER27169.1 - 0.00079 18.9 1.4 0.00079 18.9 1.0 2.9 2 1 1 3 3 3 1 PgaD-like protein TPT PF03151.11 EER27169.1 - 0.028 14.0 14.7 0.036 13.7 4.0 2.9 3 1 0 3 3 3 0 Triose-phosphate Transporter family DUF1469 PF07332.6 EER27169.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) Aldo_ket_red PF00248.16 EER27170.1 - 5.6e-53 179.5 0.0 6.4e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SLAC1 PF03595.12 EER27171.1 - 6.2e-90 301.1 54.4 7.1e-90 300.9 37.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel AA_permease PF00324.16 EER27172.1 - 6.7e-127 423.7 39.5 8e-127 423.4 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER27172.1 - 2.8e-37 128.2 41.3 3.8e-37 127.8 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM213 PF15192.1 EER27172.1 - 0.1 12.6 0.3 0.4 10.7 0.2 2.0 1 0 0 1 1 1 0 TMEM213 family SlyX PF04102.7 EER27173.1 - 0.031 14.6 9.7 0.19 12.1 0.3 3.3 4 1 0 4 4 4 0 SlyX DUF2200 PF09966.4 EER27173.1 - 0.041 13.7 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF1423 PF07227.6 EER27173.1 - 0.071 11.7 2.7 0.39 9.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1423) FTA4 PF13093.1 EER27174.1 - 1.4e-69 233.7 1.5 1.7e-69 233.5 1.1 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF148 PF02520.12 EER27174.1 - 0.03 14.1 0.3 0.065 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF148 HAD_2 PF13419.1 EER27175.1 - 4e-18 66.2 0.0 8.4e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER27175.1 - 0.00018 21.1 0.1 0.00031 20.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Ribosomal_L18p PF00861.17 EER27176.1 - 4.7e-42 142.9 0.1 4.7e-42 142.9 0.1 1.9 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EER27176.1 - 3e-32 111.0 6.6 3e-32 111.0 4.6 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region LRR_4 PF12799.2 EER27177.1 - 0.0032 17.0 3.2 3.9 7.2 0.1 5.1 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EER27177.1 - 0.004 17.0 2.4 61 4.1 0.0 6.1 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.28 EER27177.1 - 0.06 13.4 6.1 26 5.3 0.1 6.2 7 1 0 7 7 7 0 Leucine Rich Repeat F-box PF00646.28 EER27178.1 - 1.9e-06 27.3 0.1 5.2e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER27178.1 - 3.8e-05 23.3 0.1 9.7e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like ABC_membrane_2 PF06472.10 EER27179.1 - 1.2e-108 362.5 1.6 1.2e-108 362.5 1.1 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EER27179.1 - 8.5e-21 74.6 0.0 1.6e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EER27179.1 - 0.00015 21.8 0.0 0.00056 19.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EER27179.1 - 0.0082 16.4 0.3 0.034 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EER27179.1 - 0.015 14.8 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EER27179.1 - 0.028 13.6 0.2 0.095 11.9 0.0 1.9 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EER27179.1 - 0.041 13.8 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EER27179.1 - 0.057 12.6 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Phosphorylase PF00343.15 EER27180.1 - 0 1062.1 0.2 0 1061.9 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 EER27180.1 - 0.039 13.6 0.1 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Rsa3 PF14615.1 EER27180.1 - 0.042 13.1 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribosome-assembly protein 3 G-alpha PF00503.15 EER27181.1 - 2.5e-124 414.8 0.0 2.8e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EER27181.1 - 2.5e-15 56.1 1.3 2.2e-10 40.0 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER27181.1 - 6.7e-05 22.1 0.3 0.15 11.1 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EER27181.1 - 0.0019 18.6 0.9 0.73 10.3 0.2 2.9 3 1 0 3 3 3 2 Miro-like protein WAK PF08488.6 EER27181.1 - 0.037 14.3 0.1 0.33 11.2 0.0 2.2 2 0 0 2 2 2 0 Wall-associated kinase AAA_29 PF13555.1 EER27181.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 EER27182.1 - 2e-72 243.4 0.0 2.5e-72 243.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27182.1 - 6.6e-32 110.5 0.0 8.7e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EER27182.1 - 1.9e-05 23.8 0.1 6.8e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EER27182.1 - 0.0002 20.4 0.0 0.018 14.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EER27182.1 - 0.00043 20.0 0.1 0.0018 18.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EER27182.1 - 0.042 13.1 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 EER27183.1 - 5e-147 489.3 0.0 7.1e-147 488.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.4 EER27183.1 - 5.1e-09 35.8 4.2 1.2e-07 31.3 0.1 3.5 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 EER27183.1 - 6.8e-08 32.2 0.0 0.001 18.7 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis Afi1 PF07792.7 EER27183.1 - 0.0058 16.6 0.0 0.0058 16.6 0.0 3.0 3 2 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Cullin PF00888.17 EER27184.1 - 3.5e-203 676.3 9.4 5.3e-203 675.8 6.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EER27184.1 - 3.6e-28 97.1 6.9 6.1e-28 96.4 2.8 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF3887 PF13026.1 EER27184.1 - 0.0048 17.1 3.5 0.021 15.1 0.1 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3887) Abi_C PF14355.1 EER27184.1 - 0.11 12.4 0.0 0.41 10.6 0.0 2.0 1 0 0 1 1 1 0 Abortive infection C-terminus PRD PF00874.15 EER27184.1 - 1.5 8.9 5.6 2.2 8.4 0.2 3.9 5 0 0 5 5 5 0 PRD domain Cupin_1 PF00190.17 EER27185.1 - 4.2e-06 26.2 0.0 5.9e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EER27185.1 - 1.3e-05 24.6 0.1 2.1e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Cupin domain ARD PF03079.9 EER27185.1 - 0.0024 17.8 0.0 0.0033 17.3 0.0 1.2 1 0 0 1 1 1 1 ARD/ARD' family Swi3 PF07962.7 EER27185.1 - 0.059 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 Cupin_6 PF12852.2 EER27185.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 1 1 1 2 2 2 0 Cupin MARVEL PF01284.18 EER27186.1 - 0.00095 19.0 0.5 0.0017 18.1 0.3 1.4 1 0 0 1 1 1 1 Membrane-associating domain Mit_KHE1 PF10173.4 EER27187.1 - 2.1e-67 226.6 0.4 2.9e-67 226.1 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related End3 PF12761.2 EER27188.1 - 1.5e-75 253.1 0.4 2.2e-75 252.5 0.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EER27188.1 - 5.3e-51 170.7 0.2 1e-48 163.3 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EER27188.1 - 1.1e-07 30.6 0.3 2.9e-07 29.3 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EER27188.1 - 9.9e-06 25.6 0.1 7e-05 22.8 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EER27188.1 - 2.5e-05 23.7 0.5 0.00021 20.9 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EER27188.1 - 2.6e-05 23.7 0.1 7.2e-05 22.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EER27188.1 - 0.00075 18.7 1.0 0.0026 17.0 0.2 2.2 2 0 0 2 2 2 1 EF hand Rabaptin PF03528.10 EER27188.1 - 0.053 13.4 8.3 0.38 10.6 5.2 2.7 1 1 0 1 1 1 0 Rabaptin DUF4407 PF14362.1 EER27188.1 - 0.064 12.1 3.8 0.1 11.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 EER27188.1 - 0.18 11.5 0.2 0.18 11.5 0.1 2.5 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein SNF2_N PF00176.18 EER27189.1 - 1.1e-68 231.3 0.2 2.4e-68 230.1 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER27189.1 - 2.9e-16 59.0 1.1 9.3e-16 57.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER27189.1 - 1.9e-06 27.8 0.1 2.4e-05 24.2 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DSPc PF00782.15 EER27191.1 - 9.1e-13 47.9 0.2 1.9e-12 46.8 0.1 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EER27191.1 - 0.0055 15.6 0.0 0.0065 15.3 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase UK PF02512.9 EER27191.1 - 0.046 14.1 0.0 0.082 13.2 0.0 1.3 1 0 0 1 1 1 0 Virulence determinant zf-C2H2_4 PF13894.1 EER27192.1 - 4e-07 29.9 9.9 0.072 13.4 0.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EER27192.1 - 9e-07 28.8 9.7 0.0038 17.4 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type DUF4164 PF13747.1 EER27192.1 - 0.0046 17.0 2.9 0.0098 16.0 2.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) zf-H2C2_2 PF13465.1 EER27192.1 - 0.0058 16.8 13.1 0.64 10.4 1.3 3.9 3 1 0 3 3 3 2 Zinc-finger double domain IncA PF04156.9 EER27192.1 - 0.02 14.5 0.9 0.027 14.0 0.6 1.3 1 0 0 1 1 1 0 IncA protein CENP-U PF13097.1 EER27192.1 - 0.033 14.1 0.5 0.052 13.4 0.4 1.2 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit Atg14 PF10186.4 EER27192.1 - 0.036 13.0 0.5 0.044 12.7 0.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 EER27192.1 - 0.054 13.3 3.9 0.074 12.8 2.6 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 EER27192.1 - 0.061 12.8 1.7 0.11 11.9 1.2 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF1192 PF06698.6 EER27192.1 - 0.19 11.5 2.9 0.29 10.9 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) DP PF08781.5 EER27192.1 - 0.38 10.4 2.1 0.61 9.7 1.5 1.3 1 0 0 1 1 1 0 Transcription factor DP COG5 PF10392.4 EER27192.1 - 0.48 10.3 2.6 0.39 10.6 0.7 1.6 2 0 0 2 2 2 0 Golgi transport complex subunit 5 RVT_1 PF00078.22 EER27194.1 - 5.3e-09 35.7 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Urb2 PF10441.4 EER27195.1 - 4.7e-65 219.3 0.0 1.1e-64 218.0 0.0 1.7 1 0 0 1 1 1 1 Urb2/Npa2 family Myb_DNA-bind_6 PF13921.1 EER27197.1 - 7.1e-06 26.0 0.1 1.4e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER27197.1 - 0.0028 17.6 0.0 0.018 15.1 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Pkinase PF00069.20 EER27198.1 - 1.8e-29 102.7 0.0 2.3e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27198.1 - 1.8e-12 46.8 0.0 5.7e-06 25.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Suf PF05843.9 EER27200.1 - 0.016 14.9 4.6 0.019 14.7 3.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Gastrin PF00918.12 EER27200.1 - 0.054 14.2 2.9 0.11 13.2 2.0 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family XRCC4 PF06632.7 EER27200.1 - 0.12 11.2 2.6 0.15 10.8 1.8 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 BAF1_ABF1 PF04684.8 EER27200.1 - 0.38 9.5 7.4 0.56 8.9 5.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Caldesmon PF02029.10 EER27200.1 - 0.89 7.8 4.5 1 7.6 1.9 1.8 2 0 0 2 2 2 0 Caldesmon PAT1 PF09770.4 EER27200.1 - 2.3 6.3 12.9 2.7 6.1 8.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tom37_C PF11801.3 EER27201.1 - 0.00042 20.2 0.9 0.0076 16.1 0.3 2.0 1 1 1 2 2 2 1 Tom37 C-terminal domain GST_C_3 PF14497.1 EER27201.1 - 0.0079 16.6 0.1 0.0086 16.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EER27201.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_31 PF13847.1 EER27202.1 - 7.1e-14 51.6 0.0 1.3e-13 50.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER27202.1 - 6.4e-13 49.2 0.0 1e-12 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER27202.1 - 1.4e-11 44.3 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER27202.1 - 1.8e-10 41.1 0.0 7.3e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27202.1 - 1.1e-09 38.6 0.0 2.6e-09 37.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER27202.1 - 8.1e-08 32.5 0.0 2.5e-07 30.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER27202.1 - 3.3e-06 27.1 0.0 1.5e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER27202.1 - 1.2e-05 24.5 0.0 2.5e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EER27202.1 - 3e-05 23.4 0.0 4.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EER27202.1 - 0.00032 19.8 0.0 0.00045 19.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 EER27202.1 - 0.0017 17.5 0.0 0.0028 16.8 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EER27202.1 - 0.0051 16.4 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_7 PF03492.10 EER27202.1 - 0.006 15.3 0.1 0.019 13.7 0.0 1.7 2 0 0 2 2 2 1 SAM dependent carboxyl methyltransferase Methyltransf_4 PF02390.12 EER27202.1 - 0.0083 15.1 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.13 EER27202.1 - 0.013 14.7 0.0 0.62 9.3 0.0 2.4 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain PCMT PF01135.14 EER27202.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_20 PF12147.3 EER27202.1 - 0.013 14.3 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.10 EER27202.1 - 0.12 12.0 0.0 7 6.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_5 PF01795.14 EER27202.1 - 0.13 11.5 0.0 6.2 6.0 0.0 2.1 2 0 0 2 2 2 0 MraW methylase family CDC14 PF08045.6 EER27203.1 - 1.6e-91 305.9 0.0 8.2e-90 300.4 0.0 2.0 1 1 0 1 1 1 1 Cell division control protein 14, SIN component Sugar_tr PF00083.19 EER27204.1 - 2e-88 296.9 18.7 2.4e-88 296.6 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER27204.1 - 1.6e-13 50.1 43.8 1.7e-08 33.6 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UAA PF08449.6 EER27204.1 - 0.0049 15.8 0.3 0.011 14.6 0.2 1.5 1 0 0 1 1 1 1 UAA transporter family polyprenyl_synt PF00348.12 EER27205.1 - 1.1e-53 181.7 0.0 1.4e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1771 PF08590.5 EER27206.1 - 1e-23 83.1 7.8 1e-23 83.1 5.4 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 EER27206.1 - 3.9e-16 59.0 1.7 1.3e-15 57.2 0.1 2.5 2 1 1 3 3 3 1 Smr domain PAT1 PF09770.4 EER27206.1 - 2.5 6.2 11.9 3 5.9 8.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aldo_ket_red PF00248.16 EER27208.1 - 9.1e-46 155.9 0.0 1.1e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ALMT PF11744.3 EER27208.1 - 0.1 11.2 0.1 0.15 10.7 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter SicP-binding PF09119.5 EER27208.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 SicP binding Init_tRNA_PT PF04179.7 EER27209.1 - 1.5e-141 472.3 0.0 1.9e-141 472.0 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase HAD_2 PF13419.1 EER27210.1 - 8.5e-16 58.6 0.0 1.1e-15 58.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER27210.1 - 5.5e-08 32.4 0.0 9.9e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EER27210.1 - 5.1e-06 26.2 0.0 8.9e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.21 EER27210.1 - 0.00011 22.7 0.0 0.001 19.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NUDIX PF00293.23 EER27213.1 - 7.2e-18 64.5 0.0 1.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EER27214.1 - 1.7e-05 24.4 0.0 8.4e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 NUDIX domain zf-C3HC4_3 PF13920.1 EER27215.1 - 7.6e-13 47.9 6.1 1.4e-12 47.0 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER27215.1 - 2.8e-06 27.2 9.1 6e-06 26.1 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER27215.1 - 2.1e-05 24.0 8.9 4.4e-05 23.0 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER27215.1 - 0.00052 19.7 9.5 0.0012 18.6 6.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EER27215.1 - 0.0015 18.2 7.2 0.0029 17.2 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EER27215.1 - 3.4 7.3 6.4 8 6.1 4.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EST1_DNA_bind PF10373.4 EER27216.1 - 1.9e-08 33.8 5.8 3.5e-08 33.0 1.4 2.8 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain Cyclin_N PF00134.18 EER27217.1 - 0.025 14.1 0.0 1.4 8.4 0.0 2.8 3 0 0 3 3 3 0 Cyclin, N-terminal domain TFIIB PF00382.14 EER27217.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat HMGL-like PF00682.14 EER27217.1 - 0.11 12.1 0.1 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 HMGL-like Autophagy_N PF03986.8 EER27218.1 - 1e-44 151.8 0.0 2.2e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EER27218.1 - 2e-22 79.1 0.2 4.5e-22 77.9 0.1 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EER27218.1 - 2.2e-14 52.2 0.5 3.6e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal CENP-B_dimeris PF09026.5 EER27218.1 - 0.6 10.3 5.7 1.1 9.5 2.0 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EER27218.1 - 2.4 7.6 10.4 2.2 7.7 4.6 2.1 2 0 0 2 2 2 0 Nucleoplasmin SDA1 PF05285.7 EER27218.1 - 6.7 5.8 11.3 1.7 7.8 3.5 2.0 2 0 0 2 2 2 0 SDA1 Striatin PF08232.7 EER27219.1 - 0.015 15.5 0.4 0.015 15.5 0.2 1.7 2 0 0 2 2 2 0 Striatin family Glycos_transf_2 PF00535.21 EER27221.1 - 1.4e-19 70.3 0.0 5.1e-10 39.3 0.0 2.8 1 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EER27221.1 - 1e-06 28.7 0.2 0.026 14.3 0.1 3.4 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Peptidase_S10 PF00450.17 EER27222.1 - 8.5e-31 107.5 0.2 1.6e-15 57.2 0.0 3.0 1 1 2 3 3 3 3 Serine carboxypeptidase Matrilin_ccoil PF10393.4 EER27223.1 - 0.053 12.8 2.6 0.45 9.9 0.3 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2746 PF10874.3 EER27223.1 - 0.26 11.5 3.0 0.57 10.4 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Tweety PF04906.8 EER27223.1 - 1 7.6 3.9 1.5 7.1 2.7 1.1 1 0 0 1 1 1 0 Tweety FliD_N PF02465.13 EER27223.1 - 1.2 9.5 4.2 3.3 8.1 2.9 1.8 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus V_ATPase_I PF01496.14 EER27223.1 - 2.1 6.1 5.2 2.9 5.6 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ytp1 PF10355.4 EER27224.1 - 6.6e-88 294.4 12.6 6.6e-88 294.4 8.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EER27224.1 - 7.1e-30 102.6 6.2 7.1e-30 102.6 4.3 3.5 5 0 0 5 5 5 1 Domain of unknown function (DUF2427) DUF3675 PF12428.3 EER27224.1 - 0.15 12.3 1.9 3.1 8.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3675) DUF1212 PF06738.7 EER27224.1 - 2.1 7.7 14.9 0.82 9.1 2.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1212) Hydantoinase_A PF01968.13 EER27225.1 - 0.00098 18.3 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase ThiF PF00899.16 EER27226.1 - 9.2e-20 70.8 0.1 1.8e-19 69.9 0.0 1.5 2 0 0 2 2 2 1 ThiF family DUF429 PF04250.8 EER27227.1 - 0.0033 16.7 0.1 0.0059 15.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF429) MFS_1 PF07690.11 EER27228.1 - 3.9e-38 131.0 27.9 1.5e-37 129.1 19.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Acyl_transf_3 PF01757.17 EER27228.1 - 7 5.3 35.2 0.44 9.3 10.6 2.8 2 1 0 2 2 2 0 Acyltransferase family Na_H_Exchanger PF00999.16 EER27229.1 - 6.1e-71 238.9 44.4 9e-71 238.3 30.8 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Peroxin-3 PF04882.7 EER27230.1 - 5.3e-143 476.8 0.6 6.1e-143 476.6 0.4 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 EER27231.1 - 6e-68 227.6 0.0 6.8e-68 227.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) TB2_DP1_HVA22 PF03134.14 EER27232.1 - 2.1e-30 104.2 8.1 3.1e-30 103.7 5.6 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family RFX_DNA_binding PF02257.10 EER27233.1 - 3.5e-29 100.7 0.1 8e-29 99.6 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain PIG-X PF08320.7 EER27234.1 - 6.9e-70 234.5 0.0 1.1e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ PF00226.26 EER27235.1 - 1.8e-27 94.8 2.4 2.9e-27 94.1 1.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EER27235.1 - 6.2e-25 86.9 1.6 2.9e-22 78.3 0.0 2.5 2 1 0 2 2 2 2 DnaJ C terminal domain TGS PF02824.16 EER27236.1 - 4.9e-22 77.5 0.2 1e-21 76.4 0.0 1.7 2 0 0 2 2 2 1 TGS domain MMR_HSR1 PF01926.18 EER27236.1 - 5.4e-19 68.2 0.1 1.2e-18 67.1 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EER27236.1 - 1.6e-12 46.9 0.0 2.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EER27236.1 - 0.0001 22.1 0.3 0.1 12.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EER27236.1 - 0.0019 18.6 0.0 0.0044 17.5 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EER27236.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 AIG1 family ArgK PF03308.11 EER27236.1 - 0.058 12.1 0.1 0.12 11.1 0.1 1.5 1 0 0 1 1 1 0 ArgK protein RRM_1 PF00076.17 EER27237.1 - 5.7e-08 32.2 0.0 9.8e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER27237.1 - 3.4e-07 30.0 0.0 8.4e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER27237.1 - 8.9e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER27237.1 - 0.00079 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EER27237.1 - 0.13 12.0 1.6 0.22 11.2 1.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HGTP_anticodon2 PF12745.2 EER27238.1 - 1.5e-72 243.9 4.3 1.5e-72 243.9 3.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EER27238.1 - 2.2e-71 240.0 0.0 1e-35 123.1 0.0 4.5 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EER27238.1 - 3.5e-41 141.0 0.0 2.5e-18 66.1 0.0 4.0 4 0 0 4 4 4 3 Protein tyrosine kinase RWD PF05773.17 EER27238.1 - 2.9e-14 52.9 0.1 9.1e-14 51.3 0.0 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EER27238.1 - 2.7e-13 49.6 1.1 6e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 EER27238.1 - 8.4e-05 22.4 1.3 0.00022 21.1 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain APH PF01636.18 EER27238.1 - 0.0035 17.1 0.0 0.0035 17.1 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family DUF1682 PF07946.9 EER27238.1 - 0.5 9.1 13.8 1.1 8.0 9.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Cut12 PF11500.3 EER27239.1 - 6.5e-35 120.0 13.1 6.5e-35 120.0 9.1 3.8 3 1 1 4 4 4 1 Spindle pole body formation-associated protein Reo_sigmaC PF04582.7 EER27239.1 - 7.7 5.5 8.5 2.5 7.2 0.3 2.6 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF89 PF01937.14 EER27240.1 - 2.1e-98 329.4 0.0 2.3e-98 329.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 IF-2B PF01008.12 EER27240.1 - 0.031 13.2 0.1 0.048 12.6 0.0 1.3 1 1 0 1 1 1 0 Initiation factor 2 subunit family Metallophos PF00149.23 EER27241.1 - 1.9e-39 135.1 0.1 2.9e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EER27241.1 - 5.4e-31 106.4 0.8 1.1e-30 105.4 0.5 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EER27241.1 - 4.5e-20 71.0 5.0 2.4e-15 55.9 0.6 2.8 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EER27241.1 - 1.3e-09 37.2 4.2 3.6e-05 23.1 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EER27241.1 - 2.9e-09 36.1 5.1 0.0043 16.8 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EER27241.1 - 6.4e-05 22.7 0.1 0.024 14.4 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER27241.1 - 0.00011 22.1 1.5 0.16 12.2 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER27241.1 - 0.00018 22.1 4.6 0.11 13.1 0.0 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EER27241.1 - 0.0011 19.4 1.3 3.3 8.5 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EER27241.1 - 0.0049 17.2 0.2 2.2 8.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER27241.1 - 0.018 15.4 0.4 1.7 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Aminotran_3 PF00202.16 EER27242.1 - 2.7e-103 345.3 0.0 3.3e-103 345.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EER27242.1 - 0.0044 16.0 0.0 0.007 15.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Bestrophin PF01062.16 EER27243.1 - 2.7e-47 161.1 0.7 4.5e-46 157.1 0.5 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Requiem_N PF14051.1 EER27243.1 - 0.037 13.9 0.0 0.074 12.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. Sgf11 PF08209.6 EER27245.1 - 0.061 12.6 0.4 0.14 11.4 0.3 1.6 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Luteo_coat PF00894.13 EER27246.1 - 0.0051 16.5 0.1 0.068 12.9 0.0 2.2 2 0 0 2 2 2 1 Luteovirus coat protein GSH_synth_ATP PF03917.12 EER27247.1 - 1.3e-105 353.0 0.0 1.6e-105 352.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EER27247.1 - 6e-27 93.7 0.0 1.1e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EER27248.1 - 2.1e-46 158.1 0.0 4.1e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER27248.1 - 5.3e-14 51.8 0.0 1.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER27248.1 - 4.5e-08 33.1 0.0 1.4e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SAM_2 PF07647.12 EER27248.1 - 0.0071 16.1 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydrolase_3 PF07859.8 EER27249.1 - 2.9e-43 147.9 0.0 3.6e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER27249.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER27249.1 - 0.024 13.8 0.0 0.12 11.5 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF3485 PF11984.3 EER27249.1 - 0.039 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) COesterase PF00135.23 EER27249.1 - 0.041 12.5 0.1 0.1 11.2 0.0 1.5 2 0 0 2 2 2 0 Carboxylesterase family SNF2_N PF00176.18 EER27250.1 - 2.5e-72 243.1 0.0 3.5e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EER27250.1 - 2.8e-14 52.9 0.0 6.8e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.1 EER27250.1 - 4.2e-11 42.4 7.1 1.3e-10 40.9 4.9 1.9 1 0 0 1 1 1 1 Ring finger domain Helicase_C PF00271.26 EER27250.1 - 2.8e-09 36.6 0.0 1.2e-08 34.7 0.0 2.1 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EER27250.1 - 9.9e-09 35.0 7.0 9.9e-09 35.0 4.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER27250.1 - 7.9e-08 31.8 7.4 1.9e-07 30.6 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER27250.1 - 1.9e-07 30.6 3.8 1.9e-07 30.6 2.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EER27250.1 - 1e-06 28.4 7.7 1e-06 28.4 5.3 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EER27250.1 - 1.1e-06 28.6 1.7 3.2e-06 27.1 1.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 EER27250.1 - 3.4e-06 26.4 4.7 1.9e-05 24.0 3.6 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DEAD PF00270.24 EER27250.1 - 5e-06 26.1 0.0 1.1e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EER27250.1 - 2.8e-05 23.7 5.3 2.8e-05 23.7 3.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.10 EER27250.1 - 0.0012 18.7 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 EER27250.1 - 0.0013 18.4 5.3 0.0015 18.2 2.5 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EER27250.1 - 0.0024 17.6 1.3 0.0055 16.5 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EER27250.1 - 0.0076 15.6 2.7 1.4 8.4 0.3 2.7 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-RING_4 PF14570.1 EER27250.1 - 0.75 9.4 4.4 1.8 8.1 3.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RIX1 PF08167.7 EER27251.1 - 4.9e-58 195.4 3.8 2.6e-57 193.1 0.8 2.5 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis TPR_2 PF07719.12 EER27252.1 - 5.5e-08 32.1 4.6 0.057 13.3 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EER27252.1 - 1.9e-05 24.9 18.0 0.092 13.4 0.1 7.3 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER27252.1 - 2.5e-05 23.7 0.2 0.0089 15.7 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EER27252.1 - 0.00017 21.4 0.3 0.055 13.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EER27252.1 - 0.00019 21.3 7.3 8.7 6.3 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER27252.1 - 0.00032 20.9 6.2 0.026 14.8 0.1 4.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EER27252.1 - 0.00047 19.7 5.6 0.11 12.1 0.0 4.3 5 0 0 5 5 5 2 TPR repeat TPR_1 PF00515.23 EER27252.1 - 0.0054 16.2 0.9 3 7.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EER27252.1 - 0.28 11.0 9.0 9.7 6.2 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EER27252.1 - 0.54 10.8 5.8 32 5.2 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EER27252.1 - 0.57 10.9 21.5 1.2 9.8 1.3 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat NDUFA12 PF05071.11 EER27253.1 - 2.3e-26 92.2 2.3 3.1e-26 91.8 1.6 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 EER27254.1 - 9.7e-10 38.2 0.0 0.00032 20.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EER27254.1 - 3.5e-06 26.6 1.0 0.016 15.0 0.3 3.4 2 1 0 2 2 2 2 Phospholipase D Active site motif LTV PF04180.9 EER27255.1 - 1.6e-76 258.5 7.6 2e-76 258.1 5.3 1.1 1 0 0 1 1 1 1 Low temperature viability protein YL1 PF05764.8 EER27255.1 - 0.039 13.5 5.0 0.088 12.4 3.5 1.5 1 0 0 1 1 1 0 YL1 nuclear protein MMR_HSR1 PF01926.18 EER27256.1 - 2.8e-17 62.7 0.3 1.1e-14 54.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EER27256.1 - 2.6e-06 26.7 0.1 0.00011 21.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EER27256.1 - 6.4e-05 22.8 2.0 0.11 12.3 0.2 3.0 3 1 1 4 4 4 2 Dynamin family DUF258 PF03193.11 EER27256.1 - 0.00034 19.8 0.0 0.00069 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EER27256.1 - 0.0043 16.1 0.1 0.0079 15.3 0.1 1.4 1 0 0 1 1 1 1 AIG1 family RNA_pol_3_Rpc31 PF11705.3 EER27256.1 - 0.018 15.0 1.0 0.033 14.1 0.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 E3_binding PF02817.12 EER27256.1 - 0.06 12.9 0.1 0.36 10.5 0.0 2.2 2 0 0 2 2 2 0 e3 binding domain Miro PF08477.8 EER27256.1 - 0.089 13.2 0.1 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein zf-C2H2_4 PF13894.1 EER27257.1 - 0.089 13.1 12.8 0.57 10.6 0.9 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EER27258.1 - 1.7e-12 46.8 7.5 1.9e-05 24.7 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER27258.1 - 1.9e-08 34.1 2.8 1.9e-08 34.1 2.0 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER27258.1 - 2.2e-08 33.8 11.2 0.00031 20.8 2.0 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EER27258.1 - 0.00015 21.7 0.8 0.72 10.0 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EER27258.1 - 0.022 14.3 2.4 0.86 9.3 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.7 EER27258.1 - 0.046 13.8 2.3 0.1 12.7 1.6 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EER27258.1 - 0.12 12.6 2.1 3.2 8.1 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PyrI_C PF02748.10 EER27258.1 - 0.42 10.0 1.7 0.7 9.3 0.2 2.0 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_6 PF13912.1 EER27258.1 - 0.57 10.1 3.3 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EER27258.1 - 0.73 9.6 4.4 2 8.2 0.9 2.4 1 1 1 2 2 2 0 BED zinc finger Pkinase PF00069.20 EER27260.1 - 3.1e-68 229.7 0.0 7.9e-68 228.4 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27260.1 - 4.6e-50 170.1 0.0 1.8e-49 168.1 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EER27260.1 - 2.2e-32 111.0 0.0 4e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EER27260.1 - 7.7e-15 54.8 0.1 1.6e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EER27260.1 - 1.4e-13 50.4 0.1 3.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EER27260.1 - 4.6e-08 32.3 0.0 0.00018 20.5 0.0 2.7 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EER27260.1 - 3.2e-07 30.7 0.0 6.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 EER27260.1 - 0.0066 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EER27260.1 - 0.13 11.0 0.1 0.41 9.4 0.0 1.8 2 0 0 2 2 2 0 Seadornavirus VP7 Ribosomal_L5_C PF00673.16 EER27261.1 - 6e-25 86.8 0.0 1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EER27261.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.1 EER27262.1 - 2.9e-75 253.4 0.2 7.2e-74 248.8 0.0 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EER27262.1 - 1.4e-14 53.8 0.0 3.7e-14 52.4 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EnY2 PF10163.4 EER27262.1 - 0.034 14.0 0.6 1.9 8.4 0.0 3.0 3 0 0 3 3 3 0 Transcription factor e(y)2 Pep3_Vps18 PF05131.9 EER27263.1 - 2.4e-46 156.8 0.0 6.1e-46 155.5 0.0 1.8 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EER27263.1 - 2.7e-09 36.7 6.9 3.7e-06 26.5 0.1 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EER27263.1 - 0.00036 20.3 0.5 0.00088 19.0 0.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EER27263.1 - 0.0015 18.1 0.5 0.0037 16.9 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Blt1 PF12754.2 EER27263.1 - 0.058 12.9 0.1 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Cell-cycle control medial ring component DUF3849 PF12960.2 EER27263.1 - 0.074 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) DUF1664 PF07889.7 EER27263.1 - 0.11 12.2 1.3 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2175 PF09943.4 EER27263.1 - 0.12 12.4 1.0 0.29 11.2 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4 PF00097.20 EER27263.1 - 0.22 11.2 2.3 0.18 11.5 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER27263.1 - 0.36 10.8 1.3 0.82 9.7 0.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CMD PF02627.15 EER27264.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Pkinase PF00069.20 EER27266.1 - 8.4e-57 192.2 0.0 1.3e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27266.1 - 7.9e-32 110.3 0.0 1.1e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER27266.1 - 6.1e-13 48.3 0.0 5.8e-10 38.5 0.0 2.4 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 EER27266.1 - 0.017 14.1 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sad1_UNC PF07738.8 EER27267.1 - 7.4e-35 119.6 0.0 1.3e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Col_cuticle_N PF01484.12 EER27267.1 - 0.032 13.9 0.5 0.5 10.1 0.0 2.5 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.20 EER27268.1 - 9.9e-12 44.5 0.0 1.4e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27268.1 - 0.0023 17.0 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Acyl-CoA_dh_1 PF00441.19 EER27269.1 - 4e-29 101.6 2.0 6.8e-29 100.9 1.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EER27269.1 - 2.2e-16 59.0 0.0 5e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EER27269.1 - 4.6e-15 56.1 0.5 2.1e-14 54.0 0.1 2.2 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EER27269.1 - 5.7e-13 49.2 3.3 1.1e-12 48.3 2.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain EST1_DNA_bind PF10373.4 EER27270.1 - 2.4e-60 204.1 0.2 3.8e-60 203.4 0.1 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EER27270.1 - 2.8e-12 46.7 2.7 1.2e-11 44.7 1.9 2.0 1 1 0 1 1 1 1 Telomerase activating protein Est1 PfkB PF00294.19 EER27271.1 - 8.9e-66 222.0 0.0 1e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF1770 PF08589.5 EER27272.1 - 1.4e-20 73.7 3.1 1.7e-20 73.4 2.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.1 EER27273.1 - 0.0089 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.13 EER27274.1 - 2.4e-37 127.6 4.2 2.4e-37 127.6 2.9 1.4 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EER27274.1 - 1.3e-14 53.9 0.1 2.7e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3093 PF11292.3 EER27274.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Ada_Zn_binding PF02805.11 EER27275.1 - 1.9e-28 97.8 8.2 3.2e-28 97.0 5.7 1.4 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EER27275.1 - 1.2e-08 34.5 0.0 2.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EER27275.1 - 0.0002 21.3 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain MarR_2 PF12802.2 EER27275.1 - 0.068 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 MarR family RNase_H PF00075.19 EER27276.1 - 5.7e-14 52.5 0.0 8e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EER27276.1 - 0.00044 19.9 0.1 0.0051 16.5 0.1 2.2 1 1 0 1 1 1 1 Reverse transcriptase-like RtcB PF01139.12 EER27276.1 - 0.019 13.9 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB BAR PF03114.13 EER27277.1 - 8.4e-49 166.1 3.5 1.1e-48 165.7 2.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EER27277.1 - 1.5e-08 33.9 0.5 1.8e-08 33.6 0.4 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6 PF04111.7 EER27277.1 - 5.2 6.0 10.1 8 5.4 7.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EER27277.1 - 9.9 5.7 8.4 16 5.0 5.8 1.3 1 0 0 1 1 1 0 IncA protein SNF2_N PF00176.18 EER27279.1 - 1.9e-84 282.9 1.1 1.9e-84 282.9 0.8 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EER27279.1 - 3.9e-24 84.3 0.2 1.1e-23 82.9 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EER27279.1 - 1.5e-18 66.4 0.1 2.4e-17 62.5 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EER27279.1 - 1.2e-17 63.8 2.2 1.2e-17 63.8 1.5 3.9 3 1 1 4 4 4 2 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EER27279.1 - 1.4e-14 53.5 12.9 1.4e-14 53.5 8.9 2.8 3 0 0 3 3 3 1 HSA QLQ PF08880.6 EER27279.1 - 7.6e-14 50.8 2.9 7.6e-14 50.8 2.0 2.8 2 0 0 2 2 2 1 QLQ CoA_binding PF02629.14 EER27280.1 - 4.7e-26 91.1 0.6 9.2e-25 86.9 0.1 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EER27280.1 - 4.9e-22 78.1 0.2 8.1e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EER27280.1 - 8.8e-08 31.8 0.1 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EER27280.1 - 0.0021 18.2 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain Radical_SAM PF04055.16 EER27281.1 - 2.4e-19 70.1 0.1 7e-19 68.6 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EER27281.1 - 3.9e-12 46.0 0.0 1e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MARVEL PF01284.18 EER27282.1 - 0.0022 17.8 1.4 0.0025 17.6 1.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain Voltage_CLC PF00654.15 EER27282.1 - 0.007 15.4 0.8 0.0074 15.3 0.6 1.0 1 0 0 1 1 1 1 Voltage gated chloride channel DUF4064 PF13273.1 EER27282.1 - 0.022 14.8 2.6 0.061 13.4 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) TMEMspv1-c74-12 PF11044.3 EER27282.1 - 0.039 13.5 3.3 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Yip1 PF04893.12 EER27282.1 - 0.068 12.6 1.1 0.074 12.5 0.7 1.1 1 0 0 1 1 1 0 Yip1 domain Aa_trans PF01490.13 EER27282.1 - 0.069 11.6 2.3 0.18 10.2 0.0 1.9 1 1 1 2 2 2 0 Transmembrane amino acid transporter protein DUF3810 PF12725.2 EER27282.1 - 0.081 11.8 0.2 0.089 11.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) 5TM-5TMR_LYT PF07694.7 EER27282.1 - 0.095 12.0 1.8 0.19 11.0 1.3 1.5 1 1 0 1 1 1 0 5TMR of 5TMR-LYT NVEALA PF14055.1 EER27282.1 - 0.17 11.5 1.4 13 5.6 0.1 2.1 2 0 0 2 2 2 0 NVEALA protein DUF3753 PF12575.3 EER27282.1 - 0.19 11.5 0.8 1.1 9.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) His_biosynth PF00977.16 EER27283.1 - 7.2e-31 107.2 0.0 8.7e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EER27283.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF4602 PF15375.1 EER27284.1 - 4.8 7.2 15.2 2.1 8.4 8.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4602) STE PF02200.11 EER27285.1 - 3.6e-62 207.3 0.3 7e-62 206.4 0.1 1.5 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EER27285.1 - 7.6e-12 44.8 10.4 1.1e-06 28.5 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER27285.1 - 3.5e-10 39.4 9.9 3.1e-05 24.0 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EER27285.1 - 2.2e-09 37.1 11.3 2.7e-09 36.8 2.6 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EER27285.1 - 0.0012 18.7 0.2 0.0046 16.8 0.0 2.1 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EER27285.1 - 0.02 14.9 3.4 0.13 12.3 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EER27285.1 - 0.026 14.8 2.2 0.047 14.0 1.5 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger NOA36 PF06524.7 EER27285.1 - 0.074 12.3 0.6 0.13 11.5 0.4 1.3 1 0 0 1 1 1 0 NOA36 protein zf-C2HC_2 PF13913.1 EER27285.1 - 0.079 12.6 5.2 0.1 12.3 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 EER27285.1 - 0.083 12.9 0.3 0.21 11.6 0.2 1.7 1 0 0 1 1 1 0 zinc-finger FYDLN_acid PF09538.5 EER27285.1 - 0.12 13.0 4.7 0.047 14.2 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) MFS_2 PF13347.1 EER27286.1 - 1.4e-08 33.5 7.5 9.6e-07 27.5 3.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.10 EER27286.1 - 0.00067 18.4 1.3 0.0014 17.4 0.9 1.5 1 0 0 1 1 1 1 PUCC protein Na_H_Exchanger PF00999.16 EER27287.1 - 1.2e-68 231.4 37.8 1.4e-68 231.1 26.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family ADH_N PF08240.7 EER27288.1 - 9.8e-31 105.7 0.4 1.7e-30 104.9 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER27288.1 - 6.3e-25 87.2 0.2 1e-24 86.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER27288.1 - 1.9e-07 31.9 0.1 5e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glucokinase PF02685.11 EER27288.1 - 0.03 13.1 0.1 0.044 12.5 0.1 1.3 1 0 0 1 1 1 0 Glucokinase 2-Hacid_dh_C PF02826.14 EER27288.1 - 0.049 12.7 0.2 0.094 11.8 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNF2_N PF00176.18 EER27289.1 - 1.6e-70 237.2 3.1 1.6e-70 237.2 2.2 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EER27289.1 - 1.2e-50 171.1 23.0 1.2e-50 171.1 16.0 4.3 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EER27289.1 - 5.6e-17 61.3 0.0 2.8e-16 59.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Aminotran_1_2 PF00155.16 EER27290.1 - 2.3e-82 276.8 0.0 3e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EER27290.1 - 3.3e-07 28.9 0.0 5.2e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EER27290.1 - 1.8e-06 26.9 0.0 3.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EER27290.1 - 0.0033 16.5 0.1 0.0076 15.3 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EER27290.1 - 0.0035 16.5 0.2 0.013 14.6 0.1 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase RNA_pol_I_A49 PF06870.7 EER27291.1 - 2.5e-50 171.1 0.0 3.2e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Ribosomal_L41 PF05162.8 EER27292.1 - 9.5e-09 34.7 25.2 1e-08 34.7 17.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 EER27292.1 - 0.18 11.4 1.3 0.2 11.3 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) GATase PF00117.23 EER27293.1 - 2.6e-47 160.7 0.0 3.6e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EER27293.1 - 3e-45 152.9 0.0 5.2e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EER27293.1 - 0.00014 21.3 0.3 0.0068 15.8 0.1 2.5 1 1 1 2 2 2 2 Peptidase C26 Peptidase_S10 PF00450.17 EER27294.1 - 9.9e-92 308.2 4.2 7.6e-90 302.0 2.9 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase PARP PF00644.15 EER27295.1 - 1e-63 214.4 2.0 4.2e-63 212.4 0.0 2.8 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EER27295.1 - 1.5e-39 134.7 0.1 2.3e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EER27295.1 - 4e-22 77.9 0.7 1.3e-21 76.3 0.5 1.9 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 EER27295.1 - 4.8e-14 52.2 0.4 1.6e-13 50.5 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EER27295.1 - 1.5e-09 37.5 0.1 3.3e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain SOBP PF15279.1 EER27295.1 - 0.23 11.7 9.8 0.37 11.1 6.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein DUF500 PF04366.7 EER27296.1 - 7e-44 148.2 0.0 1.3e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) ETF PF01012.16 EER27297.1 - 7.4e-36 123.3 0.2 9.6e-36 122.9 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Flavodoxin_1 PF00258.20 EER27298.1 - 1.1e-31 109.7 0.0 1.3e-29 103.0 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.15 EER27298.1 - 3.1e-31 108.5 0.0 6.1e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EER27298.1 - 1.9e-14 54.1 0.0 1.8e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EER27298.1 - 3.8e-05 23.7 0.2 0.13 12.2 0.0 2.7 2 1 1 3 3 3 2 Flavodoxin domain Flavodoxin_3 PF12641.2 EER27298.1 - 0.028 13.8 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain RNA_pol_3_Rpc31 PF11705.3 EER27299.1 - 3.3e-54 184.3 2.2 3.9e-54 184.0 1.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Proteasom_PSMB PF10508.4 EER27300.1 - 0.1 10.8 0.1 5.4 5.1 0.0 2.3 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit JAB PF01398.16 EER27301.1 - 2.1e-07 30.6 0.0 4.4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Solute_trans_a PF03619.11 EER27302.1 - 1.2e-87 293.7 21.2 1.4e-87 293.4 14.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha PrgI PF12666.2 EER27302.1 - 0.025 14.7 1.2 0.025 14.7 0.9 2.8 2 1 0 2 2 2 0 PrgI family protein SAP PF02037.22 EER27303.1 - 1.5e-08 33.9 0.2 4e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 EER27303.1 - 0.035 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Abhydrolase_1 PF00561.15 EER27304.1 - 1e-43 149.5 0.2 1.2e-42 146.1 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EER27304.1 - 1.8e-15 57.4 2.7 3.3e-14 53.3 1.8 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27304.1 - 0.0001 22.0 0.1 0.0025 17.5 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EER27304.1 - 0.0033 17.2 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein MFS_1 PF07690.11 EER27305.1 - 1.2e-23 83.3 30.1 6.5e-17 61.2 17.2 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily APH PF01636.18 EER27306.1 - 1.7e-06 27.9 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_M36 PF02128.10 EER27307.1 - 1.7e-162 540.5 2.8 2.1e-162 540.2 2.0 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EER27307.1 - 8.1e-15 54.0 3.7 1.3e-14 53.3 1.8 2.0 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Prenyltrans PF00432.16 EER27307.1 - 0.029 13.9 0.4 0.7 9.5 0.1 2.9 3 0 0 3 3 3 0 Prenyltransferase and squalene oxidase repeat Peptidase_MA_2 PF13485.1 EER27307.1 - 0.059 13.4 0.1 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Tho2 PF11262.3 EER27309.1 - 2e-92 309.4 0.0 2.9e-92 308.9 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EER27309.1 - 1.1e-30 105.2 0.5 4e-30 103.4 0.0 2.3 2 0 0 2 2 2 1 Transcription- and export-related complex subunit GFA PF04828.9 EER27310.1 - 9.2e-16 57.5 0.2 1.4e-15 57.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EER27310.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.7 3 0 0 3 3 3 0 Nudix N-terminal Vps5 PF09325.5 EER27311.1 - 2.7e-13 49.7 5.4 5.6e-13 48.6 3.7 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EER27311.1 - 2.5e-09 36.9 0.0 6e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 PX domain TPR_12 PF13424.1 EER27311.1 - 0.069 13.0 1.8 0.38 10.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat GTP_EFTU PF00009.22 EER27312.1 - 5e-51 172.8 0.0 9e-51 171.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EER27312.1 - 7.9e-26 89.7 0.1 5.4e-25 87.0 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 EER27312.1 - 7.6e-19 67.3 0.0 3.5e-09 36.4 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EER27312.1 - 5e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EER27312.1 - 0.0015 18.1 0.1 0.029 13.9 0.0 2.8 3 0 0 3 3 3 1 Elongation factor G, domain IV RRM_1 PF00076.17 EER27314.1 - 1.3e-30 104.7 0.1 3.2e-15 55.5 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER27314.1 - 7.6e-25 86.6 0.0 4.1e-12 45.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER27314.1 - 2.3e-10 40.1 0.0 0.00025 20.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRE_C2HC PF07530.6 EER27314.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Associated with zinc fingers API5 PF05918.6 EER27314.1 - 0.14 10.6 4.7 0.19 10.1 3.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MARVEL PF01284.18 EER27316.1 - 6.4e-07 29.2 10.5 1.4e-06 28.1 7.4 1.5 1 1 1 2 2 2 2 Membrane-associating domain TPMT PF05724.6 EER27317.1 - 5.9e-29 101.0 0.0 7.3e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_23 PF13489.1 EER27317.1 - 5.3e-06 26.2 0.0 7.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER27317.1 - 8.1e-06 26.3 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER27317.1 - 1.1e-05 25.1 0.0 0.00011 21.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER27317.1 - 0.00018 21.5 0.0 0.00033 20.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27317.1 - 0.00019 21.8 0.0 0.00031 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER27317.1 - 0.0014 19.0 0.0 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EER27317.1 - 0.0024 17.0 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.7 EER27317.1 - 0.0046 15.9 0.0 0.0061 15.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein AdoMet_MTase PF07757.8 EER27317.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase PALP PF00291.20 EER27318.1 - 6.8e-37 127.3 0.1 7.6e-37 127.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 EER27318.1 - 0.11 12.0 0.3 0.38 10.3 0.2 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Homeobox_KN PF05920.6 EER27319.1 - 3.1e-16 58.8 0.3 9.1e-16 57.2 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EER27319.1 - 5.7e-10 38.6 0.7 1.3e-09 37.4 0.5 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EER27319.1 - 0.013 14.5 0.1 0.028 13.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez zf-C2H2 PF00096.21 EER27319.1 - 0.09 13.1 0.7 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type Methyltransf_3 PF01596.12 EER27320.1 - 1.1e-13 50.6 0.1 1.4e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EER27320.1 - 6.8e-09 36.5 0.0 9.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EER27320.1 - 0.00049 19.4 0.0 0.00092 18.5 0.0 1.6 1 1 0 1 1 1 1 Cephalosporin hydroxylase RNA12 PF10443.4 EER27320.1 - 0.077 11.4 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein DUF2119 PF09892.4 EER27320.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) HPP PF04982.8 EER27322.1 - 4.7e-37 126.4 5.6 4.7e-37 126.4 3.9 1.9 2 0 0 2 2 2 1 HPP family DUF599 PF04654.7 EER27322.1 - 0.053 12.6 2.5 0.45 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF599 Bax1-I PF01027.15 EER27322.1 - 7.6 6.0 10.9 19 4.7 7.5 1.6 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 ABC_tran PF00005.22 EER27323.1 - 8.4e-47 158.9 0.0 1e-22 80.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EER27323.1 - 4.6e-21 76.0 0.4 0.00026 21.0 0.0 4.4 3 1 1 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EER27323.1 - 3.3e-20 71.7 1.9 3.3e-20 71.7 1.3 3.1 4 1 0 4 4 2 1 ABC transporter SMC_N PF02463.14 EER27323.1 - 1e-10 41.2 0.3 0.0057 15.9 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EER27323.1 - 8.2e-09 34.8 0.3 0.00059 19.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EER27323.1 - 1.8e-08 35.0 2.4 0.026 14.8 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EER27323.1 - 2e-06 28.6 0.1 0.026 15.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EER27323.1 - 2.2e-06 28.0 0.3 0.033 14.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EER27323.1 - 3.6e-06 26.2 0.0 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EER27323.1 - 3.6e-05 24.2 0.0 0.13 12.7 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EER27323.1 - 5.1e-05 23.4 0.1 0.22 11.6 0.1 2.9 2 2 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EER27323.1 - 9.5e-05 22.2 0.3 1.5 8.6 0.0 4.1 3 1 1 4 4 4 2 Dynamin family NACHT PF05729.7 EER27323.1 - 0.00011 21.9 0.2 0.4 10.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EER27323.1 - 0.00012 22.0 0.0 0.069 13.1 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EER27323.1 - 0.00014 21.8 1.0 0.17 11.8 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 EER27323.1 - 0.00066 19.8 0.8 1.5 9.0 0.0 3.1 3 0 0 3 3 3 2 RNA helicase AAA_15 PF13175.1 EER27323.1 - 0.00076 18.6 0.1 0.32 9.9 0.0 3.1 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 EER27323.1 - 0.00094 19.0 0.0 0.36 10.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EER27323.1 - 0.0017 18.5 0.0 1.3 9.2 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EER27323.1 - 0.0025 17.5 0.1 0.87 9.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EER27323.1 - 0.0035 17.0 0.1 3.3 7.3 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase AAA_28 PF13521.1 EER27323.1 - 0.0047 16.9 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EER27323.1 - 0.0047 16.3 0.0 0.82 9.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain NB-ARC PF00931.17 EER27323.1 - 0.0052 15.6 0.0 3 6.6 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain AAA_10 PF12846.2 EER27323.1 - 0.0075 15.7 1.5 1 8.7 0.2 2.9 3 0 0 3 3 2 1 AAA-like domain AAA_14 PF13173.1 EER27323.1 - 0.0094 15.8 0.0 1.8 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EER27323.1 - 0.0097 15.8 1.1 0.85 9.5 0.1 3.6 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EER27323.1 - 0.02 14.5 0.3 0.19 11.4 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 EER27323.1 - 0.031 13.7 0.2 3.9 6.9 0.0 3.0 3 0 0 3 3 3 0 Virulence-associated protein E DAP3 PF10236.4 EER27323.1 - 0.08 11.8 0.9 14 4.5 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.18 EER27323.1 - 0.11 11.2 2.0 5.5 5.6 0.0 2.6 3 0 0 3 3 3 0 MCM2/3/5 family AAA_24 PF13479.1 EER27323.1 - 0.65 9.5 4.1 9.6 5.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_13 PF13166.1 EER27323.1 - 1.7 6.9 9.9 15 3.8 0.2 4.5 4 1 1 5 5 5 0 AAA domain Cyclin_N PF00134.18 EER27324.1 - 6.6e-05 22.4 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA PF00004.24 EER27325.1 - 4.3e-41 140.2 0.0 8.8e-41 139.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER27325.1 - 2.8e-07 30.7 0.2 0.00013 22.1 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EER27325.1 - 2.7e-06 27.4 0.0 5.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EER27325.1 - 5.4e-05 22.2 0.0 9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EER27325.1 - 7.9e-05 22.4 0.1 0.00023 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EER27325.1 - 0.00094 19.2 0.1 0.0061 16.5 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EER27325.1 - 0.00096 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EER27325.1 - 0.0013 18.3 0.4 0.0031 17.2 0.3 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EER27325.1 - 0.0026 17.7 0.1 0.0026 17.7 0.1 2.3 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 EER27325.1 - 0.0037 16.6 0.0 0.0088 15.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EER27325.1 - 0.0079 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EER27325.1 - 0.0096 15.5 0.3 0.72 9.4 0.1 2.7 2 1 1 3 3 2 1 NACHT domain TIP49 PF06068.8 EER27325.1 - 0.013 14.2 0.1 0.033 12.9 0.0 1.6 1 1 0 1 1 1 0 TIP49 C-terminus AAA_17 PF13207.1 EER27325.1 - 0.016 15.9 0.4 0.057 14.2 0.3 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EER27325.1 - 0.017 15.0 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EER27325.1 - 0.02 14.0 0.4 0.29 10.2 0.1 2.4 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 EER27325.1 - 0.02 14.0 0.6 0.46 9.6 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.6 EER27325.1 - 0.033 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EER27325.1 - 0.037 14.3 0.2 0.085 13.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EER27325.1 - 0.062 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EER27325.1 - 0.075 11.8 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 EER27325.1 - 0.08 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EER27325.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SKI PF01202.17 EER27325.1 - 0.1 12.4 0.1 2.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase Mg_chelatase PF01078.16 EER27325.1 - 0.12 11.5 0.1 0.25 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EER27325.1 - 0.14 11.7 0.2 0.36 10.3 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EER27325.1 - 0.5 9.7 6.0 0.57 9.5 0.3 2.9 2 1 1 3 3 3 0 AAA domain UQ_con PF00179.21 EER27326.1 - 2e-42 143.9 0.0 2.7e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EER27326.1 - 3.8e-07 29.5 0.0 8.6e-07 28.4 0.0 1.6 1 1 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EER27326.1 - 0.0004 20.1 0.1 0.00094 18.9 0.0 1.5 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EER27326.1 - 0.081 12.8 1.4 0.087 12.7 0.0 1.8 2 1 0 2 2 2 0 RWD domain WD40 PF00400.27 EER27327.1 - 1e-21 75.9 18.7 9.5e-07 28.4 0.5 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Mg_trans_NIPA PF05653.9 EER27328.1 - 3.9e-63 213.2 5.8 3.9e-59 200.0 2.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EER27328.1 - 0.00049 20.2 0.4 0.00049 20.2 0.3 3.1 3 1 0 3 3 3 1 Multidrug resistance efflux transporter CD20 PF04103.10 EER27328.1 - 3.5 7.5 11.2 2.5 8.0 0.1 3.2 4 0 0 4 4 4 0 CD20-like family Lebercilin PF15619.1 EER27329.1 - 0.03 13.7 5.0 0.57 9.5 0.5 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Med30 PF11315.3 EER27329.1 - 0.067 13.3 4.9 2.6 8.1 0.1 2.4 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF4047 PF13256.1 EER27329.1 - 0.07 13.0 1.6 0.11 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) HALZ PF02183.13 EER27329.1 - 0.59 9.8 4.9 2.4 7.9 0.7 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 EER27329.1 - 1.8 8.9 4.1 17 5.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) EI24 PF07264.6 EER27330.1 - 5e-07 29.3 19.0 1e-06 28.3 13.2 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF1600 PF07667.6 EER27330.1 - 0.32 11.1 4.6 0.13 12.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) GRAM PF02893.15 EER27331.1 - 5.9e-17 60.9 0.0 2.8e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 GRAM domain adh_short PF00106.20 EER27332.1 - 2.9e-07 30.5 0.0 5.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER27332.1 - 0.0064 16.1 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Tn916-Xis PF09035.5 EER27332.1 - 0.15 12.2 0.0 9.7 6.3 0.0 2.8 2 1 1 3 3 3 0 Excisionase from transposon Tn916 Cu_amine_oxid PF01179.15 EER27333.1 - 3.5e-171 569.4 0.1 4.2e-171 569.2 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EER27333.1 - 1.3e-18 66.9 0.3 1.6e-17 63.3 0.0 2.4 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EER27333.1 - 3.3e-16 59.1 0.0 5.6e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF1 PF04857.15 EER27334.1 - 6.2e-65 219.1 0.0 9.5e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease Sporozoite_P67 PF05642.6 EER27334.1 - 0.037 11.9 1.4 0.06 11.1 0.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NDUF_B12 PF08122.7 EER27335.1 - 2.1e-19 68.9 0.4 3e-19 68.5 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family WD40 PF00400.27 EER27336.1 - 3.4e-32 109.1 5.8 2.9e-06 26.9 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EER27336.1 - 3e-06 26.6 0.0 0.18 11.3 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Acetyltransf_1 PF00583.19 EER27337.1 - 1e-08 35.0 0.1 2.7e-08 33.7 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER27337.1 - 1.3e-07 31.7 0.0 2e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EER27337.1 - 3.7e-07 30.6 0.0 5.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER27337.1 - 0.0021 17.9 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EER27337.1 - 0.0097 16.0 0.0 0.034 14.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER27337.1 - 0.035 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AMP-binding PF00501.23 EER27338.1 - 8.3e-78 261.6 0.0 1.1e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER27338.1 - 5.9e-13 49.5 0.0 1.4e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 EER27339.1 - 3.9e-22 79.0 0.0 1.3e-21 77.3 0.0 1.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CNH PF00780.17 EER27340.1 - 3.8e-72 242.9 0.0 5.9e-72 242.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EER27340.1 - 1.7e-30 106.2 1.9 3.6e-30 105.1 1.1 1.8 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.1 EER27340.1 - 9.2e-14 51.5 0.0 4.7e-13 49.2 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EER27340.1 - 1.5e-05 25.1 0.0 3.9e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 PH domain RabGAP-TBC PF00566.13 EER27341.1 - 1.5e-45 155.3 0.0 2.6e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EER27341.1 - 0.011 15.5 0.1 0.011 15.5 0.1 2.9 4 0 0 4 4 4 0 EF-hand domain GRAM PF02893.15 EER27341.1 - 0.027 13.9 0.0 0.07 12.6 0.0 1.8 1 1 0 1 1 1 0 GRAM domain COMP PF11598.3 EER27341.1 - 0.058 13.4 0.1 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein NDUF_B5 PF09781.4 EER27342.1 - 0.1 11.8 0.2 0.2 10.8 0.2 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit adh_short_C2 PF13561.1 EER27344.1 - 7.8e-20 71.6 0.3 1.4e-19 70.8 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER27344.1 - 5.3e-17 62.2 1.0 8.5e-17 61.5 0.7 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER27344.1 - 1.3e-05 24.9 0.1 2.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1772 PF08592.6 EER27345.1 - 0.044 13.5 0.3 0.08 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) BatA PF07584.6 EER27345.1 - 1 9.5 3.7 2.3 8.4 0.7 2.5 2 1 1 3 3 3 0 Aerotolerance regulator N-terminal AMP-binding PF00501.23 EER27347.1 - 1.2e-76 257.8 0.0 1.5e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER27347.1 - 1.1e-12 48.7 0.5 2.4e-12 47.6 0.3 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF706 PF05153.10 EER27348.1 - 1.3e-128 427.6 2.4 1.6e-128 427.3 1.7 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EER27348.1 - 0.083 12.9 0.0 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 HD domain RTA1 PF04479.8 EER27349.1 - 1.6e-49 168.4 0.4 2.3e-49 167.9 0.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Exo_endo_phos PF03372.18 EER27350.1 - 1.2e-19 71.2 0.4 1.4e-19 70.9 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RTC PF01137.16 EER27351.1 - 3.6e-37 127.3 0.0 6.6e-24 83.9 0.0 3.0 2 1 0 2 2 2 2 RNA 3'-terminal phosphate cyclase SH3_9 PF14604.1 EER27354.1 - 6e-14 51.3 0.1 1e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EER27354.1 - 3e-12 45.7 0.1 5.2e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EER27354.1 - 5.3e-12 45.7 1.6 7.9e-12 45.1 1.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_2 PF07653.12 EER27354.1 - 4.1e-11 42.2 0.0 7.2e-10 38.2 0.1 2.7 3 0 0 3 3 3 1 Variant SH3 domain DUF2439 PF10382.4 EER27355.1 - 1.1e-23 83.1 0.0 1.9e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Methyltransf_23 PF13489.1 EER27356.1 - 3e-15 56.2 0.0 4.8e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER27356.1 - 1.2e-07 32.0 0.0 3.6e-07 30.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27356.1 - 1.1e-06 29.0 0.0 2.8e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER27356.1 - 1.2e-06 28.2 0.0 1.1e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER27356.1 - 2.3e-06 28.1 0.0 3.7e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER27357.1 - 9.9e-17 61.1 0.0 1.8e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER27357.1 - 1.3e-11 44.7 0.0 4.7e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER27357.1 - 4.2e-09 36.9 0.0 3.7e-08 33.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER27357.1 - 6.1e-09 35.6 0.0 9.7e-08 31.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27357.1 - 2e-06 28.1 0.0 1.2e-05 25.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER27357.1 - 0.00021 20.4 0.0 0.0047 16.0 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EER27357.1 - 0.003 17.8 0.0 0.0087 16.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EER27357.1 - 0.0036 16.7 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EER27357.1 - 0.0074 16.3 0.0 0.048 13.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EER27357.1 - 0.0093 15.1 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EER27357.1 - 0.049 12.6 0.0 0.31 10.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 EER27357.1 - 0.077 12.3 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain PCMT PF01135.14 EER27357.1 - 0.13 11.7 0.0 0.88 9.0 0.0 2.0 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.17 EER27358.1 - 3.3e-58 197.3 0.0 4e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ku PF02735.11 EER27359.1 - 3.9e-36 124.3 0.0 6.6e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EER27359.1 - 4.2e-32 111.3 0.0 7e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EER27359.1 - 1.3e-13 51.2 0.3 3.3e-13 49.9 0.2 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EER27359.1 - 1e-10 40.8 0.0 2.1e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 SAP domain TAF8_C PF10406.4 EER27359.1 - 0.093 12.8 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 Transcription factor TFIID complex subunit 8 C-term CMAS PF02353.15 EER27360.1 - 0.0061 15.6 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase zf-C3HC4_2 PF13923.1 EER27362.1 - 3.1e-08 33.4 10.5 5.7e-08 32.6 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EER27362.1 - 4.5e-08 32.5 2.5 8.3e-08 31.7 1.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EER27362.1 - 6.6e-08 32.1 4.9 1.1e-07 31.4 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER27362.1 - 2.2e-07 30.6 7.3 3.6e-07 29.9 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EER27362.1 - 2.4e-07 30.2 11.0 4.3e-07 29.4 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER27362.1 - 3.2e-06 26.7 9.6 5.4e-06 26.0 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EER27362.1 - 0.00027 20.7 9.1 0.0006 19.6 6.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EER27362.1 - 0.002 17.5 3.0 0.004 16.6 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EER27362.1 - 0.0021 17.7 5.9 0.0052 16.4 4.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Cript PF10235.4 EER27362.1 - 0.026 14.8 3.4 0.058 13.7 1.7 2.2 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT zf-rbx1 PF12678.2 EER27362.1 - 1.9 8.6 6.0 4.5 7.4 4.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Mcp5_PH PF12814.2 EER27363.1 - 5.9e-43 145.6 0.1 1.2e-42 144.7 0.1 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology DUF1664 PF07889.7 EER27363.1 - 2 8.1 7.0 12 5.7 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 EER27363.1 - 6.2 6.3 40.8 0.018 14.6 16.5 3.3 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 SKG6 PF08693.5 EER27364.1 - 6.4e-08 31.7 0.1 1.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EER27364.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Toxin_24 PF08094.6 EER27364.1 - 1.8 8.2 8.0 9.1 5.9 1.7 2.7 2 0 0 2 2 2 0 Conotoxin TVIIA/GS family MFS_1 PF07690.11 EER27365.1 - 7.3e-25 87.4 35.9 3.7e-24 85.0 13.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ferrochelatase PF00762.14 EER27366.1 - 3.7e-90 302.1 0.0 4.2e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase PPR PF01535.15 EER27367.1 - 6.6e-07 28.8 5.3 0.027 14.4 0.0 6.0 6 0 0 6 6 6 2 PPR repeat PPR_2 PF13041.1 EER27367.1 - 3.3e-06 26.9 0.7 0.19 11.7 0.0 4.8 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 EER27367.1 - 2.3e-05 24.3 0.1 0.079 13.2 0.0 5.4 6 0 0 6 6 6 1 Pentatricopeptide repeat domain TPR_12 PF13424.1 EER27367.1 - 0.055 13.4 0.6 1.5 8.7 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SE PF08491.5 EER27368.1 - 2.4e-96 321.8 0.0 3e-96 321.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EER27368.1 - 1.9e-09 36.8 0.1 6.7e-07 28.5 0.3 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EER27368.1 - 1.3e-08 34.3 0.0 3.1e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EER27368.1 - 4.3e-07 29.1 1.4 2.7e-05 23.2 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EER27368.1 - 4.9e-05 23.2 0.5 9.6e-05 22.3 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EER27368.1 - 0.00029 19.8 0.6 0.00062 18.7 0.4 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EER27368.1 - 0.00051 19.9 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER27368.1 - 0.00096 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EER27368.1 - 0.0013 17.7 0.3 0.0029 16.5 0.2 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EER27368.1 - 0.0014 17.1 0.5 0.0022 16.5 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EER27368.1 - 0.002 17.2 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EER27368.1 - 0.0092 16.3 0.2 0.024 15.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EER27368.1 - 0.083 12.3 0.2 0.16 11.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 EER27368.1 - 0.1 10.8 0.1 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor Trp_halogenase PF04820.9 EER27368.1 - 0.23 10.0 0.6 0.53 8.8 0.2 1.6 1 1 0 2 2 2 0 Tryptophan halogenase PAP_assoc PF03828.14 EER27369.1 - 2.6e-17 62.5 0.0 6.1e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EER27369.1 - 1.1e-06 28.8 0.0 2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Zwint PF15556.1 EER27370.1 - 0.17 11.1 2.1 0.25 10.5 1.5 1.1 1 0 0 1 1 1 0 ZW10 interactor DUF914 PF06027.7 EER27371.1 - 1.7e-107 359.1 19.6 2.2e-107 358.8 13.6 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EER27371.1 - 0.00018 21.5 29.6 0.00024 21.1 7.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EER27371.1 - 1 9.0 23.7 0.26 10.9 2.6 2.9 3 0 0 3 3 3 0 Triose-phosphate Transporter family SMK-1 PF04802.10 EER27372.1 - 1.4e-74 249.8 0.5 2.6e-74 248.9 0.4 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF2305 PF10230.4 EER27373.1 - 8.2e-64 215.5 0.0 9.9e-54 182.5 0.0 2.1 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EER27373.1 - 7.3e-06 25.7 0.2 1.6e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EER27373.1 - 7.2e-05 22.7 0.1 0.00025 20.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27373.1 - 0.00016 21.4 0.0 0.00036 20.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 EER27373.1 - 0.0016 17.2 0.1 0.0029 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta-hydrolase family DUF900 PF05990.7 EER27373.1 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 EER27373.1 - 0.036 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EER27373.1 - 0.036 14.2 0.0 0.066 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 EER27373.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.3 EER27373.1 - 0.099 11.7 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DLH PF01738.13 EER27373.1 - 0.15 11.2 0.0 0.61 9.3 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family DCP1 PF06058.8 EER27374.1 - 1e-17 64.3 0.0 1.9e-17 63.4 0.0 1.4 1 1 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 EER27375.1 - 1.8e-18 67.3 0.2 2.8e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EER27375.1 - 0.031 13.8 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain PhoU PF01895.14 EER27376.1 - 0.065 13.6 1.8 11 6.5 0.0 2.4 1 1 1 2 2 2 0 PhoU domain LMP PF04778.7 EER27376.1 - 0.066 12.9 2.1 0.13 12.0 1.4 1.5 1 0 0 1 1 1 0 LMP repeated region HSBP1 PF06825.7 EER27376.1 - 0.097 12.2 5.8 0.17 11.4 0.7 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Spore_GerAC PF05504.6 EER27376.1 - 0.11 12.2 0.2 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Baculo_PEP_C PF04513.7 EER27376.1 - 0.2 11.4 1.1 0.44 10.3 0.7 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.9 EER27376.1 - 0.21 11.1 4.0 0.34 10.4 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) OmpH PF03938.9 EER27376.1 - 0.32 10.9 4.1 0.53 10.2 2.9 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EER27376.1 - 0.96 9.0 8.8 2.3 7.7 6.1 1.6 1 1 0 1 1 1 0 IncA protein STE3 PF02076.10 EER27377.1 - 4.5e-95 317.9 12.2 5.2e-95 317.7 8.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor SSB PF00436.20 EER27378.1 - 1.4e-10 40.9 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family Erf4 PF10256.4 EER27379.1 - 3.8e-33 113.8 0.0 5.8e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Adap_comp_sub PF00928.16 EER27380.1 - 8.5e-86 287.2 0.0 1.1e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EER27380.1 - 9.4e-05 22.1 0.2 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 EER27381.1 - 6.5e-61 205.7 0.1 1.3e-55 188.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER27381.1 - 3.2e-27 95.2 0.0 1.1e-24 86.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 EER27381.1 - 3.1e-11 43.2 0.0 8.6e-11 41.8 0.0 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EER27381.1 - 2.2e-05 23.5 0.0 3.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER27381.1 - 0.0002 21.1 0.1 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EER27381.1 - 0.0008 18.5 0.4 0.0024 16.9 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EER27381.1 - 0.0016 17.8 0.1 0.0053 16.1 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EER27381.1 - 0.029 13.1 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Myb_DNA-bind_6 PF13921.1 EER27382.1 - 1.2e-05 25.2 0.0 2.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER27382.1 - 0.013 15.5 0.3 0.032 14.2 0.1 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain PBP1_TM PF14812.1 EER27382.1 - 0.49 10.7 5.5 0.43 10.9 2.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ank PF00023.25 EER27384.1 - 0.00025 20.7 0.2 0.00058 19.5 0.2 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EER27384.1 - 0.00038 20.5 0.0 0.00082 19.5 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER27384.1 - 0.002 18.1 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat zf-C2H2_2 PF12756.2 EER27384.1 - 0.05 13.7 0.2 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ank_2 PF12796.2 EER27384.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-met PF12874.2 EER27384.1 - 0.12 12.6 0.7 0.25 11.6 0.5 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Gluconate_2-dh3 PF13618.1 EER27384.1 - 0.19 11.8 4.8 0.82 9.8 0.0 2.7 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 ABC_membrane PF00664.18 EER27385.1 - 6e-74 248.9 31.5 4.3e-40 137.8 7.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EER27385.1 - 4.3e-51 172.8 0.0 5.2e-29 101.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EER27385.1 - 6.3e-12 45.1 1.9 0.00024 20.4 0.1 4.1 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EER27385.1 - 9.3e-07 29.0 1.6 0.035 14.1 0.5 2.7 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EER27385.1 - 4.2e-06 26.7 0.0 0.088 12.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EER27385.1 - 2.8e-05 24.2 3.2 0.25 11.2 0.0 4.6 5 0 0 5 5 4 1 AAA domain AAA_25 PF13481.1 EER27385.1 - 5.9e-05 22.5 0.0 0.073 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EER27385.1 - 6.3e-05 22.4 0.0 0.18 11.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EER27385.1 - 0.00014 21.0 0.0 0.027 13.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EER27385.1 - 0.00043 20.6 0.0 0.031 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EER27385.1 - 0.00083 19.2 0.2 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EER27385.1 - 0.00096 19.6 1.1 1.3 9.5 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein AAA_30 PF13604.1 EER27385.1 - 0.0013 18.3 0.6 2.7 7.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EER27385.1 - 0.0058 16.4 0.3 0.95 9.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EER27385.1 - 0.012 15.1 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EER27385.1 - 0.021 15.6 0.0 7.8 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EER27385.1 - 0.025 13.4 0.0 0.58 8.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EER27385.1 - 0.031 13.7 1.3 6.1 6.1 0.1 2.8 2 1 1 3 3 3 0 AAA-like domain AAA_22 PF13401.1 EER27385.1 - 0.037 14.1 1.2 4 7.5 0.0 3.3 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EER27385.1 - 0.066 12.6 0.0 6.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 EER27385.1 - 0.093 11.8 0.1 7.2 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 EER27385.1 - 0.14 12.3 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EER27385.1 - 0.15 11.7 0.0 8.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EER27385.1 - 0.21 11.9 0.3 32 4.8 0.0 2.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EER27385.1 - 0.96 9.0 4.4 1.5 8.4 0.1 3.0 3 0 0 3 3 3 0 NACHT domain DUF2841 PF11001.3 EER27386.1 - 1.8e-49 166.7 0.4 2.8e-49 166.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SAC3_GANP PF03399.11 EER27387.1 - 3.6e-54 183.4 1.7 5.4e-54 182.8 1.2 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EER27387.1 - 0.00019 21.2 0.2 0.00053 19.7 0.2 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 HC2 PF07382.6 EER27387.1 - 0.14 12.0 19.9 0.28 11.0 13.8 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 PGAP1 PF07819.8 EER27388.1 - 7.6e-07 28.9 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 EER27388.1 - 1.2e-05 24.9 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 EER27388.1 - 2.1e-05 24.5 0.0 4.1e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27388.1 - 0.00061 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_14 PF13173.1 EER27388.1 - 0.0013 18.6 0.1 0.08 12.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain DUF676 PF05057.9 EER27388.1 - 0.002 17.4 0.0 0.0046 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_22 PF13401.1 EER27388.1 - 0.029 14.4 0.0 0.62 10.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EER27388.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain LCAT PF02450.10 EER27388.1 - 0.047 12.6 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NB-ARC PF00931.17 EER27388.1 - 0.058 12.2 0.2 0.96 8.2 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain DUF2075 PF09848.4 EER27388.1 - 0.074 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0565 PF10561.4 EER27388.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 RNA_helicase PF00910.17 EER27388.1 - 0.15 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF3089 PF11288.3 EER27388.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) CN_hydrolase PF00795.17 EER27389.1 - 1.1e-11 44.4 0.0 3.7e-10 39.4 0.0 2.4 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase HLH PF00010.21 EER27390.1 - 1.2e-13 50.5 0.6 2.3e-13 49.5 0.4 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PLC-beta_C PF08703.5 EER27390.1 - 0.085 12.5 3.2 0.16 11.6 2.2 1.4 1 0 0 1 1 1 0 PLC-beta C terminal Sec8_exocyst PF04048.9 EER27391.1 - 2.3e-42 143.9 0.4 1.6e-41 141.3 0.1 2.4 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EER27391.1 - 9.2e-10 37.8 0.0 2.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Zw10 PF06248.8 EER27391.1 - 0.0069 14.6 0.0 0.012 13.7 0.0 1.3 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.1 EER27391.1 - 0.022 14.5 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 DHquinase_I PF01487.10 EER27391.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Type I 3-dehydroquinase COG2 PF06148.6 EER27391.1 - 0.068 13.0 0.2 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Peptidase_M24 PF00557.19 EER27392.1 - 3.5e-40 137.7 0.1 5.2e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EER27392.1 - 7.6e-27 94.4 0.1 2.2e-21 76.7 0.0 2.8 3 0 0 3 3 3 2 Creatinase/Prolidase N-terminal domain Tap-RNA_bind PF09162.5 EER27392.1 - 0.17 11.4 0.2 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 Tap, RNA-binding IBN_N PF03810.14 EER27393.1 - 0.0025 17.7 0.1 0.0084 16.0 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain RIX1 PF08167.7 EER27393.1 - 0.039 13.6 1.2 1.8 8.2 0.1 3.0 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Bcl-2 PF00452.14 EER27393.1 - 0.093 12.8 0.0 4.2 7.5 0.0 3.5 4 0 0 4 4 4 0 Apoptosis regulator proteins, Bcl-2 family SOR_SNZ PF01680.12 EER27394.1 - 1.4e-110 367.8 4.1 1.4e-110 367.8 2.9 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EER27394.1 - 7.9e-11 41.4 3.1 8.4e-08 31.5 0.0 2.5 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EER27394.1 - 0.00034 19.5 0.1 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EER27394.1 - 0.00077 18.7 0.1 0.025 13.8 0.0 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EER27394.1 - 0.0032 16.5 0.0 0.033 13.2 0.0 2.3 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EER27394.1 - 0.0034 16.3 0.4 0.08 11.9 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.19 EER27394.1 - 0.0052 16.2 0.2 0.36 10.1 0.0 2.5 1 1 1 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TMP-TENI PF02581.12 EER27394.1 - 0.024 13.7 0.5 0.64 9.1 0.0 2.9 3 0 0 3 3 3 0 Thiamine monophosphate synthase/TENI NMO PF03060.10 EER27394.1 - 0.045 12.9 4.5 0.12 11.5 0.0 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase MttA_Hcf106 PF02416.11 EER27394.1 - 0.11 11.6 0.1 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 mttA/Hcf106 family TPR_14 PF13428.1 EER27395.1 - 0.021 15.4 0.1 0.46 11.2 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Aegerolysin PF06355.8 EER27396.1 - 5.5e-42 142.7 0.2 6.2e-42 142.5 0.1 1.0 1 0 0 1 1 1 1 Aegerolysin zf-CDGSH PF09360.5 EER27396.1 - 0.0033 17.2 0.0 0.007 16.1 0.0 1.7 2 0 0 2 2 2 1 Iron-binding zinc finger CDGSH type Amidinotransf PF02274.12 EER27397.1 - 2.5e-13 49.7 0.0 4.4e-11 42.3 0.0 3.0 1 1 0 1 1 1 1 Amidinotransferase p450 PF00067.17 EER27398.1 - 1.5e-59 201.7 0.0 2e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EER27399.1 - 3.4e-33 114.8 0.0 4.6e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FUN14 PF04930.10 EER27400.1 - 5e-10 39.5 0.6 1.4e-09 38.1 0.4 1.7 1 1 0 1 1 1 1 FUN14 family ORC2 PF04084.9 EER27401.1 - 7.1e-98 327.4 0.0 8.4e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Uteroglobin PF01099.12 EER27401.1 - 0.29 10.9 1.6 16 5.3 0.1 2.5 2 0 0 2 2 2 0 Uteroglobin family Ndc1_Nup PF09531.5 EER27401.1 - 1.9 6.7 6.2 3 6.1 4.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ArgJ PF01960.13 EER27402.1 - 2.4e-147 490.3 0.0 2.8e-147 490.1 0.0 1.0 1 0 0 1 1 1 1 ArgJ family ATP_sub_h PF10775.4 EER27402.1 - 0.21 11.3 0.8 0.44 10.3 0.1 1.8 2 0 0 2 2 2 0 ATP synthase complex subunit h SecY PF00344.15 EER27403.1 - 5.4e-98 328.1 6.8 6.7e-98 327.7 4.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EER27403.1 - 2.7e-18 65.1 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p GFA PF04828.9 EER27404.1 - 2.2e-13 49.9 1.3 2.2e-13 49.9 0.9 2.0 2 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EER27404.1 - 0.39 10.6 8.1 0.11 12.4 1.8 2.5 3 0 0 3 3 3 0 Cysteine-rich CWC Ank_2 PF12796.2 EER27405.1 - 1.5e-28 98.9 9.6 2.5e-09 37.3 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER27405.1 - 1.8e-26 91.9 8.2 1.7e-08 34.7 0.2 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EER27405.1 - 2.8e-26 89.9 8.7 4.7e-06 26.1 0.1 5.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EER27405.1 - 3.4e-22 77.9 10.0 1.2e-06 28.5 0.4 3.5 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER27405.1 - 2.5e-21 73.6 6.2 5.2e-05 23.0 0.0 5.2 5 0 0 5 5 5 5 Ankyrin repeat DUF2520 PF10728.4 EER27405.1 - 0.044 13.2 2.5 0.11 11.9 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF2520) CARM1 PF11531.3 EER27405.1 - 0.072 12.8 0.5 2.8 7.6 0.1 2.5 1 1 0 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal FdtA PF05523.6 EER27405.1 - 0.21 11.1 1.1 1.2 8.5 0.1 2.3 2 1 0 2 2 2 0 WxcM-like, C-terminal MUG113 PF13455.1 EER27406.1 - 2.7e-26 91.8 0.4 2.7e-26 91.8 0.3 3.0 2 1 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EER27406.1 - 4e-18 65.6 0.2 4e-18 65.6 0.2 2.8 4 1 0 4 4 4 1 T5orf172 domain zf-primase PF09329.6 EER27406.1 - 0.11 12.1 0.2 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 Primase zinc finger ABC_membrane PF00664.18 EER27407.1 - 3.1e-92 308.8 38.1 6.6e-49 166.7 12.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EER27407.1 - 7.6e-67 223.8 0.0 2.9e-32 111.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EER27407.1 - 6.2e-15 55.0 0.0 7.5e-05 22.0 0.0 4.0 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER27407.1 - 2.4e-12 47.4 0.3 0.024 14.6 0.0 4.4 2 2 0 4 4 4 4 AAA domain AAA_16 PF13191.1 EER27407.1 - 7.9e-09 35.7 1.1 0.00028 20.9 0.0 3.2 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EER27407.1 - 1.3e-08 34.2 1.3 0.00054 19.4 0.3 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EER27407.1 - 5.6e-08 33.6 0.0 0.02 15.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EER27407.1 - 4.7e-07 29.1 0.6 0.046 12.9 0.1 3.2 3 0 0 3 3 3 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 EER27407.1 - 2.7e-06 26.2 2.0 0.015 13.9 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 EER27407.1 - 4e-06 26.3 0.2 0.064 12.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EER27407.1 - 2.5e-05 24.4 2.3 0.38 10.9 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EER27407.1 - 8.5e-05 22.8 0.0 0.47 10.7 0.0 3.1 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.17 EER27407.1 - 0.00012 21.6 0.3 0.32 10.4 0.0 2.9 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA PF00004.24 EER27407.1 - 0.00014 22.0 3.2 8 6.6 0.0 4.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EER27407.1 - 0.0002 21.2 0.1 0.68 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EER27407.1 - 0.00034 20.1 0.8 2 7.7 0.0 3.9 4 0 0 4 4 4 2 AAA-like domain AAA_5 PF07728.9 EER27407.1 - 0.00062 19.5 0.6 1.6 8.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EER27407.1 - 0.00072 19.1 6.6 1.7 8.1 0.0 4.7 4 1 0 4 4 4 2 AAA domain SbcCD_C PF13558.1 EER27407.1 - 0.0023 17.8 4.2 1 9.3 0.2 3.7 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.10 EER27407.1 - 0.0023 16.6 0.3 0.09 11.4 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 EER27407.1 - 0.0024 17.6 0.4 2.6 7.7 0.1 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EER27407.1 - 0.0056 16.3 2.8 1.6 8.5 0.2 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_28 PF13521.1 EER27407.1 - 0.0058 16.6 0.4 1.5 8.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EER27407.1 - 0.013 15.3 0.1 3.6 7.5 0.0 3.7 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 EER27407.1 - 0.015 15.4 0.1 3.2 7.9 0.0 3.0 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EER27407.1 - 0.02 13.9 1.5 4.9 6.1 0.0 3.4 4 0 0 4 4 4 0 Zeta toxin MMR_HSR1 PF01926.18 EER27407.1 - 0.037 13.9 2.0 13 5.7 0.0 3.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EER27407.1 - 0.058 13.7 4.0 4.7 7.4 0.3 3.3 3 0 0 3 3 3 0 AAA domain PRK PF00485.13 EER27407.1 - 0.076 12.5 0.0 12 5.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.12 EER27407.1 - 1.3 8.7 4.9 13 5.5 0.1 2.8 3 0 0 3 3 2 0 Domain of unknown function DUF87 Ribosomal_L39 PF00832.15 EER27408.1 - 1.3e-22 79.0 9.0 1.4e-22 78.8 6.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 EER27408.1 - 0.12 11.8 0.9 0.14 11.6 0.6 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Skp1 PF01466.14 EER27409.1 - 1.1e-39 134.3 2.0 1.9e-39 133.5 1.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EER27409.1 - 3.8e-23 81.3 0.1 8.5e-23 80.2 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain CM_2 PF01817.16 EER27409.1 - 0.028 14.5 0.0 0.076 13.1 0.0 1.7 1 0 0 1 1 1 0 Chorismate mutase type II SERTA PF06031.8 EER27409.1 - 0.29 10.4 1.8 0.56 9.5 0.1 2.3 2 1 0 2 2 2 0 SERTA motif Glyco_transf_22 PF03901.12 EER27410.1 - 6.1e-50 170.4 16.3 3.9e-28 98.5 1.9 2.2 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family XPC-binding PF09280.6 EER27411.1 - 2.7e-23 81.2 15.7 5.9e-23 80.0 10.9 1.6 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EER27411.1 - 4.2e-21 74.1 0.5 6.2e-21 73.5 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EER27411.1 - 6.8e-20 70.3 2.2 3e-09 36.4 0.1 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EER27411.1 - 3.7e-09 36.1 0.4 6.5e-09 35.3 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EER27411.1 - 0.00059 19.3 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rap1_C PF11626.3 EER27411.1 - 0.0061 16.4 0.0 0.71 9.7 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Ubiquitin_2 PF14560.1 EER27411.1 - 0.0062 16.7 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EER27411.1 - 0.0065 16.6 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EER27411.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EER27411.1 - 0.022 15.2 0.1 0.046 14.2 0.1 1.5 1 0 0 1 1 1 0 MCM N-terminal domain UBA_2 PF08587.6 EER27411.1 - 0.1 12.7 0.0 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) F-box PF00646.28 EER27412.1 - 0.035 13.7 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain Aminotran_1_2 PF00155.16 EER27413.1 - 3.2e-44 151.3 0.0 4.5e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EER27413.1 - 1.4e-08 33.8 0.0 2.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EER27413.1 - 2.2e-06 26.2 0.0 3.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EER27413.1 - 6.2e-05 22.2 0.0 0.0001 21.5 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EER27413.1 - 0.0088 15.1 0.0 0.02 13.9 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Methyltransf_22 PF13383.1 EER27414.1 - 0.023 14.2 0.3 0.038 13.5 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase domain eIF-6 PF01912.13 EER27415.1 - 9e-83 276.2 0.7 1.2e-82 275.8 0.5 1.1 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 EER27415.1 - 0.098 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Phage holin family 6 SET PF00856.23 EER27416.1 - 2.1e-22 80.1 0.6 2.1e-22 80.1 0.4 4.1 3 2 0 3 3 3 1 SET domain SRI PF08236.6 EER27416.1 - 3.4e-21 74.9 13.7 3.4e-21 74.9 9.5 2.2 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 EER27416.1 - 5.4e-05 22.9 1.3 0.00013 21.7 0.9 1.7 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 EER27416.1 - 0.0045 16.4 0.1 0.013 14.9 0.0 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3287 PF11690.3 EER27416.1 - 0.0087 16.1 1.1 0.0087 16.1 0.8 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3287) CENP-X PF09415.5 EER27416.1 - 0.18 11.6 1.0 0.56 10.0 0.7 1.8 1 0 0 1 1 1 0 CENP-S associating Centromere protein X AT_hook PF02178.14 EER27417.1 - 0.069 12.8 3.2 0.25 11.1 2.2 2.0 1 0 0 1 1 1 0 AT hook motif BAR PF03114.13 EER27418.1 - 1.3e-56 191.7 3.4 1.7e-56 191.3 2.3 1.1 1 0 0 1 1 1 1 BAR domain HrpB2 PF09487.5 EER27418.1 - 0.075 13.2 0.4 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) Arfaptin PF06456.8 EER27418.1 - 0.5 9.6 4.2 1.7 7.9 2.9 2.0 1 1 0 1 1 1 0 Arfaptin-like domain DUF1204 PF06721.6 EER27418.1 - 0.55 9.4 6.4 0.042 13.0 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1204) Pkinase PF00069.20 EER27419.1 - 7.9e-60 202.1 0.0 1.5e-59 201.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27419.1 - 1e-36 126.3 0.0 2e-34 118.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EER27419.1 - 1.1e-07 31.1 0.0 4.9e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EER27419.1 - 0.0021 17.8 0.2 0.025 14.3 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Rota_NS53 PF00981.12 EER27419.1 - 0.26 9.8 0.0 0.4 9.2 0.0 1.2 1 0 0 1 1 1 0 Rotavirus RNA-binding Protein 53 (NS53) Sybindin PF04099.7 EER27420.1 - 2.5e-26 92.0 0.0 3.3e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EER27420.1 - 0.00095 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EER27421.1 - 7.1e-65 218.7 0.0 9.8e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27421.1 - 1e-28 100.1 0.0 1.5e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER27421.1 - 0.0048 15.8 0.0 0.014 14.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EER27421.1 - 0.0096 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER27421.1 - 0.11 12.2 0.6 1.8 8.2 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Methyltransf_23 PF13489.1 EER27422.1 - 6.4e-13 48.7 0.0 1.3e-12 47.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER27422.1 - 1.3e-07 32.2 0.0 3.5e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER27422.1 - 1.4e-06 27.9 0.0 6.6e-06 25.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER27422.1 - 3e-05 24.4 0.0 0.00027 21.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER27422.1 - 0.00023 21.4 0.0 0.00069 19.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER27422.1 - 0.008 16.6 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER27422.1 - 0.01 15.2 0.0 0.34 10.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EER27422.1 - 0.01 14.9 0.0 0.023 13.8 0.0 1.7 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4447 PF14590.1 EER27422.1 - 0.06 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) PhyH PF05721.8 EER27423.1 - 5.5e-09 36.3 0.1 2.1e-08 34.4 0.1 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NQRA PF05896.6 EER27423.1 - 0.18 10.9 0.3 6 5.9 0.1 2.1 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Brix PF04427.13 EER27424.1 - 4.4e-37 127.6 0.1 6.7e-37 127.0 0.1 1.3 1 0 0 1 1 1 1 Brix domain CDC45 PF02724.9 EER27424.1 - 0.049 11.6 2.5 0.071 11.1 1.7 1.2 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_2b PF00587.20 EER27425.1 - 1.8e-66 222.9 0.1 2.6e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EER27425.1 - 9.9e-21 73.4 0.0 9.9e-21 73.4 0.0 2.5 3 1 0 3 3 3 1 Anticodon binding domain Pkinase PF00069.20 EER27427.1 - 4.4e-72 242.3 0.0 8.4e-72 241.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27427.1 - 2.1e-52 177.8 0.0 3.9e-52 176.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH_11 PF15413.1 EER27427.1 - 2.8e-23 82.2 0.7 7.1e-23 81.0 0.5 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PBD PF00786.23 EER27427.1 - 1e-22 80.2 0.3 1.2e-21 76.8 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain PH PF00169.24 EER27427.1 - 2.3e-10 40.6 0.2 4.9e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EER27427.1 - 3.4e-06 26.2 0.0 6.8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER27427.1 - 0.015 15.0 4.1 0.023 14.4 0.1 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EER27427.1 - 0.023 13.5 0.0 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NAD_kinase PF01513.16 EER27428.1 - 8.5e-50 169.1 0.0 1.4e-49 168.4 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase Acyltransferase PF01553.16 EER27429.1 - 9.5e-28 96.2 0.0 1.8e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase TPR_11 PF13414.1 EER27430.1 - 2.3e-28 97.6 27.2 4.3e-07 29.4 0.0 9.5 8 1 0 9 9 9 5 TPR repeat TPR_2 PF07719.12 EER27430.1 - 5.8e-28 94.5 16.8 0.0046 16.7 0.0 11.6 12 0 0 12 12 11 8 Tetratricopeptide repeat TPR_1 PF00515.23 EER27430.1 - 3.9e-21 73.6 19.1 0.0087 15.6 0.0 10.6 11 0 0 11 11 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 EER27430.1 - 7.8e-21 72.2 17.4 0.011 15.4 0.1 11.2 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EER27430.1 - 5.7e-20 71.4 14.4 4e-06 27.0 0.2 8.7 7 3 2 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 EER27430.1 - 2.2e-18 65.9 24.8 9.8e-07 28.6 0.1 9.8 8 2 3 11 11 10 4 Tetratricopeptide repeat TPR_14 PF13428.1 EER27430.1 - 2.1e-13 49.6 36.9 0.0025 18.3 0.0 12.6 14 3 3 17 17 11 4 Tetratricopeptide repeat TPR_16 PF13432.1 EER27430.1 - 2.6e-12 47.0 42.7 0.00043 20.8 0.0 11.6 11 1 1 13 13 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 EER27430.1 - 7.3e-10 38.2 14.3 0.29 11.4 0.1 10.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_7 PF13176.1 EER27430.1 - 1.1e-07 31.1 25.1 0.02 14.6 0.0 10.0 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.1 EER27430.1 - 0.00016 21.9 34.7 0.66 10.5 0.0 12.4 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_10 PF13374.1 EER27430.1 - 0.00079 19.2 9.6 0.12 12.3 0.0 6.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 EER27430.1 - 0.016 15.5 3.2 2.3 8.8 0.9 4.2 3 0 0 3 3 2 0 Tetratricopeptide repeat LOH1CR12 PF10158.4 EER27430.1 - 0.032 14.0 0.2 0.032 14.0 0.2 2.9 3 1 0 3 3 3 0 Tumour suppressor protein PPR PF01535.15 EER27430.1 - 0.037 14.0 0.2 34 4.7 0.0 4.1 4 0 0 4 4 3 0 PPR repeat TPR_3 PF07720.7 EER27430.1 - 0.07 12.9 15.8 0.93 9.3 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat SGL PF08450.7 EER27431.1 - 6.7e-29 100.9 0.1 2.2e-27 96.0 0.1 2.1 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EER27431.1 - 0.024 14.6 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 Arylesterase Str_synth PF03088.11 EER27431.1 - 0.046 13.7 0.0 0.23 11.5 0.0 2.2 2 1 0 2 2 2 0 Strictosidine synthase PBD PF00786.23 EER27432.1 - 0.052 13.9 1.9 0.21 12.0 1.3 2.1 1 0 0 1 1 1 0 P21-Rho-binding domain Pkinase PF00069.20 EER27433.1 - 6.6e-14 51.6 0.1 9.8e-13 47.8 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27433.1 - 0.00038 19.6 0.1 0.001 18.1 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase HNH_2 PF13391.1 EER27434.1 - 1.8e-14 53.2 0.1 1.6e-13 50.2 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease Es2 PF09751.4 EER27435.1 - 6.2e-113 378.3 2.9 7.1e-113 378.1 2.0 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 Mid1 PF12929.2 EER27436.1 - 1.7e-148 494.8 1.9 2.1e-148 494.6 1.3 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EER27436.1 - 0.05 13.9 2.7 3.3 8.0 0.2 2.5 2 0 0 2 2 2 0 Fz domain Kin17_mid PF10357.4 EER27437.1 - 2.3e-52 175.9 0.4 4.9e-52 174.8 0.3 1.6 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EER27437.1 - 0.00022 21.3 3.1 0.00044 20.3 2.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EER27437.1 - 0.00027 20.9 2.1 0.00057 19.9 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EER27437.1 - 0.045 13.8 1.0 0.045 13.8 0.7 2.2 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) CorA PF01544.13 EER27438.1 - 5e-40 137.3 0.0 8.4e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Trefoil PF00088.13 EER27439.1 - 9.1 6.0 8.4 2.5 7.7 1.1 2.7 3 0 0 3 3 3 0 Trefoil (P-type) domain zf-rbx1 PF12678.2 EER27440.1 - 1.2e-35 121.4 12.7 1.5e-35 121.1 8.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EER27440.1 - 3.6e-17 61.9 9.7 4.7e-17 61.6 6.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EER27440.1 - 1.9e-07 30.8 12.1 1.1e-06 28.3 8.4 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EER27440.1 - 0.002 17.7 11.3 0.031 13.9 7.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER27440.1 - 0.0031 17.1 9.2 0.24 11.0 6.5 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER27440.1 - 0.027 14.4 12.2 0.65 10.0 8.5 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EER27440.1 - 0.13 12.2 8.8 0.55 10.2 6.2 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.1 EER27440.1 - 0.91 9.5 9.6 2.1 8.3 6.7 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EER27440.1 - 1.2 9.3 10.5 65 3.7 7.3 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EER27440.1 - 2 8.1 6.4 49 3.7 4.4 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EER27440.1 - 2.2 8.0 11.3 17 5.2 7.8 2.3 1 1 0 1 1 1 0 zinc-RING finger domain PNRC PF15365.1 EER27441.1 - 2.8e-08 33.6 4.3 5.9e-07 29.3 2.0 3.4 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator SMI1_KNR4 PF09346.5 EER27442.1 - 7.2e-35 119.8 0.0 1.2e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Thioredoxin PF00085.15 EER27443.1 - 0.063 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin DIM1 PF02966.11 EER27443.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF2997 PF11211.3 EER27443.1 - 0.25 10.7 0.8 0.72 9.2 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2997) Zn_clus PF00172.13 EER27444.1 - 6.8e-10 38.6 9.5 1.4e-09 37.7 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF791 PF05631.9 EER27445.1 - 1.2e-63 214.9 1.8 1.7e-63 214.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EER27445.1 - 1e-20 73.7 18.1 1e-20 73.7 12.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER27445.1 - 6.3e-11 41.5 1.7 6.3e-11 41.5 1.2 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EER27445.1 - 0.013 15.2 0.6 0.066 13.0 0.2 2.5 2 0 0 2 2 2 0 MFS_1 like family ATG22 PF11700.3 EER27445.1 - 0.018 13.5 8.7 0.13 10.6 6.1 2.3 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like DUF3318 PF11780.3 EER27445.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) DUF4516 PF14990.1 EER27445.1 - 0.056 12.9 0.0 0.23 11.0 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) DUF21 PF01595.15 EER27445.1 - 0.25 10.6 4.9 0.14 11.4 0.2 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF21 Methyltransf_22 PF13383.1 EER27446.1 - 2e-31 109.4 0.0 2.5e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EER27446.1 - 5.8e-06 26.3 0.0 9.2e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF829 PF05705.9 EER27448.1 - 1.7e-53 181.7 0.0 2.1e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) WRW PF10206.4 EER27448.1 - 0.084 12.9 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f UFD1 PF03152.9 EER27449.1 - 8.8e-76 252.9 0.0 1.1e-75 252.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EER27449.1 - 0.0015 18.1 0.0 0.029 14.0 0.0 2.3 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 GYF PF02213.11 EER27450.1 - 2.1e-09 36.8 0.2 4.8e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 GYF domain TIP49 PF06068.8 EER27451.1 - 3.4e-174 579.2 2.4 4e-174 578.9 1.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EER27451.1 - 2.8e-08 34.0 0.1 3.3e-05 24.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EER27451.1 - 1.2e-07 31.0 1.0 6e-05 22.2 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EER27451.1 - 6.1e-06 25.3 0.3 1e-05 24.6 0.2 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EER27451.1 - 8.6e-05 22.5 0.0 0.00046 20.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EER27451.1 - 0.00033 20.7 0.0 0.24 11.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EER27451.1 - 0.0049 16.0 0.7 0.068 12.3 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EER27451.1 - 0.006 16.4 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EER27451.1 - 0.0062 16.2 0.1 0.53 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EER27451.1 - 0.0099 15.2 0.1 0.02 14.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EER27451.1 - 0.014 14.8 0.0 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 EER27451.1 - 0.024 14.4 0.4 0.087 12.5 0.2 2.0 1 1 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 EER27451.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EER27451.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DNA_pol3_delta PF06144.8 EER27451.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 EER27451.1 - 0.14 11.6 0.9 0.46 9.9 0.0 2.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family DUF4041 PF13250.1 EER27452.1 - 0.14 11.7 1.8 30 4.2 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) FlaC_arch PF05377.6 EER27452.1 - 0.25 11.2 23.7 1 9.3 0.6 6.3 6 2 0 6 6 6 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 EER27452.1 - 1.2 9.4 17.9 1.5 9.1 0.0 5.5 4 2 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Borrelia_REV PF03978.8 EER27452.1 - 1.8 8.2 15.5 0.054 13.2 1.4 3.4 2 2 1 3 3 3 0 Borrelia burgdorferi REV protein RPW8 PF05659.6 EER27452.1 - 4.8 6.7 13.0 2.3 7.7 1.5 3.5 2 2 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Baculo_PEP_C PF04513.7 EER27452.1 - 5.4 6.8 22.8 0.75 9.6 0.4 4.2 2 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FSH1 PF03959.8 EER27453.1 - 8.6e-26 90.7 0.0 1.1e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EER27453.1 - 0.00095 18.6 0.2 0.073 12.5 0.0 2.7 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EER27453.1 - 0.0015 18.4 0.0 0.028 14.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27453.1 - 0.0028 17.3 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family ORC6 PF05460.8 EER27455.1 - 0.0012 18.0 1.7 0.0013 17.9 1.2 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) HTH_Mga PF08280.6 EER27455.1 - 0.013 15.1 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Myb_DNA-binding PF00249.26 EER27456.1 - 0.0022 18.0 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EER27456.1 - 0.038 14.1 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain ORC6 PF05460.8 EER27456.1 - 0.097 11.7 3.5 0.11 11.6 2.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ORC6 PF05460.8 EER27459.1 - 0.27 10.2 8.8 0.32 10.0 6.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Med3 PF11593.3 EER27459.1 - 0.98 8.5 7.1 1 8.5 4.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Herpes_DNAp_acc PF04929.7 EER27459.1 - 1.3 7.8 5.2 1.7 7.5 3.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Abp2 PF09441.5 EER27460.1 - 3.5e-80 268.0 0.0 5.8e-80 267.3 0.0 1.3 1 0 0 1 1 1 1 ARS binding protein 2 TENA_THI-4 PF03070.11 EER27460.1 - 0.067 12.9 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 TENA/THI-4/PQQC family WW PF00397.21 EER27462.1 - 4.8e-05 23.1 0.9 0.00011 21.9 0.7 1.7 1 0 0 1 1 1 1 WW domain Brix PF04427.13 EER27463.1 - 2e-29 102.6 0.0 2.6e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain CDC45 PF02724.9 EER27463.1 - 0.22 9.4 3.9 0.2 9.6 1.6 1.7 2 0 0 2 2 2 0 CDC45-like protein BTV_NS2 PF04514.7 EER27463.1 - 0.9 8.3 4.2 1.7 7.4 2.9 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 F-box-like PF12937.2 EER27464.1 - 0.0026 17.4 0.3 0.061 13.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like Ribosomal_L14e PF01929.12 EER27464.1 - 0.014 15.7 0.1 0.073 13.4 0.1 2.0 2 0 0 2 2 2 0 Ribosomal protein L14 DUF1838 PF08894.6 EER27464.1 - 0.017 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1838) DUF2573 PF10835.3 EER27464.1 - 0.13 12.3 0.0 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) Ras PF00071.17 EER27465.1 - 4.3e-63 211.5 0.2 5.1e-63 211.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER27465.1 - 1.4e-21 77.2 0.1 2e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER27465.1 - 5.6e-13 48.4 0.1 7.6e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EER27465.1 - 3.2e-08 33.5 0.1 5.3e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER27465.1 - 4.7e-05 22.9 0.1 0.00017 21.1 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EER27465.1 - 5.8e-05 23.2 0.2 0.00017 21.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain Gtr1_RagA PF04670.7 EER27465.1 - 7.6e-05 21.9 0.2 0.00013 21.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EER27465.1 - 0.0011 18.8 0.1 0.003 17.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EER27465.1 - 0.0015 17.6 0.0 0.0019 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EER27465.1 - 0.0027 16.9 0.1 0.0061 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EER27465.1 - 0.0062 16.4 0.1 0.085 12.7 0.0 2.2 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EER27465.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EER27465.1 - 0.015 15.2 0.4 0.047 13.6 0.2 1.9 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EER27465.1 - 0.016 15.5 0.1 0.022 15.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EER27465.1 - 0.025 14.1 0.6 0.047 13.2 0.1 1.8 2 1 1 3 3 3 0 AAA domain AAA_29 PF13555.1 EER27465.1 - 0.11 12.0 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EER27465.1 - 0.11 11.8 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 EER27465.1 - 0.11 12.4 1.0 0.17 11.8 0.7 1.5 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EER27465.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Chromo PF00385.19 EER27466.1 - 1e-10 41.0 0.4 3e-10 39.6 0.2 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SPT6_acidic PF14632.1 EER27466.1 - 5.4 7.2 7.2 39 4.4 0.4 3.6 3 0 0 3 3 3 0 Acidic N-terminal SPT6 AAA_2 PF07724.9 EER27467.1 - 1.2e-37 129.4 0.0 1e-36 126.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EER27467.1 - 1.2e-14 54.6 0.0 2.6e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EER27467.1 - 1.1e-09 37.9 0.0 2.6e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EER27467.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EER27467.1 - 0.00013 21.1 0.2 0.0087 15.2 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EER27467.1 - 0.00058 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 EER27467.1 - 0.00094 18.6 0.0 0.073 12.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 EER27467.1 - 0.001 19.8 0.0 0.0027 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EER27467.1 - 0.0011 19.1 0.2 0.012 15.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EER27467.1 - 0.0014 18.0 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER27467.1 - 0.0019 18.2 1.1 0.0051 16.8 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EER27467.1 - 0.0028 17.2 0.0 0.0067 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EER27467.1 - 0.0063 15.5 0.2 0.14 11.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EER27467.1 - 0.027 14.3 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EER27467.1 - 0.039 12.7 0.1 0.088 11.6 0.1 1.5 1 1 0 1 1 1 0 MCM2/3/5 family RNA_helicase PF00910.17 EER27467.1 - 0.044 13.9 0.0 0.093 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EER27467.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EER27467.1 - 0.064 13.5 0.0 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EER27467.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FAD_binding_4 PF01565.18 EER27468.1 - 2e-17 62.9 0.7 3.8e-17 62.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EER27468.1 - 8.4e-11 41.6 0.1 1.7e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ATP-synt_ab PF00006.20 EER27469.1 - 1.4e-61 207.7 0.0 2.3e-61 207.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EER27469.1 - 2.4e-25 89.1 0.8 4.1e-25 88.4 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EER27469.1 - 2.3e-23 82.1 2.7 4.7e-23 81.1 1.1 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 EER27469.1 - 0.0022 17.4 0.3 0.031 13.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EER27469.1 - 0.0059 16.3 0.0 0.019 14.6 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EER27469.1 - 0.0068 16.4 0.3 0.3 11.0 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EER27469.1 - 0.013 15.6 0.1 0.47 10.6 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EER27469.1 - 0.018 14.2 0.1 0.033 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 EER27469.1 - 0.023 13.8 0.1 0.044 12.8 0.1 1.5 1 0 0 1 1 1 0 KaiC MobB PF03205.9 EER27469.1 - 0.024 14.3 0.2 1.3 8.7 0.0 3.0 3 1 1 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EER27469.1 - 0.026 14.1 0.1 0.072 12.7 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EER27469.1 - 0.062 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EER27469.1 - 0.069 13.2 0.0 0.34 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EER27469.1 - 0.095 13.2 0.0 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 EER27469.1 - 0.14 10.9 0.8 0.62 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 EER27470.1 - 3.3e-27 94.4 0.2 2.6e-26 91.5 0.1 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EER27470.1 - 8.8e-19 68.0 0.1 6.5e-15 55.3 0.1 2.8 2 1 1 3 3 3 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EER27470.1 - 9.2e-18 64.0 0.0 2.6e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 EER27470.1 - 0.051 12.4 0.3 0.33 9.8 0.0 2.1 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme COX4 PF02936.9 EER27471.1 - 3.7e-49 166.1 0.7 4.6e-49 165.8 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.8 EER27471.1 - 4.6 6.7 5.6 4.4 6.8 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Cofilin_ADF PF00241.15 EER27472.1 - 5.1e-24 84.5 0.0 5.7e-24 84.4 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cpn60_TCP1 PF00118.19 EER27473.1 - 1.6e-117 393.1 9.0 1.8e-117 392.9 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EER27473.1 - 0.25 11.0 1.4 0.75 9.5 0.2 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) B5 PF03484.10 EER27474.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetase B5 domain ATP-synt_Eps PF04627.8 EER27475.1 - 2.2e-21 75.1 1.4 3.4e-21 74.5 1.0 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Mak10 PF04112.8 EER27476.1 - 5.2e-51 172.2 0.0 9.6e-51 171.3 0.0 1.5 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Fascin PF06268.8 EER27476.1 - 0.021 14.9 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Fascin domain NAGLU_N PF12971.2 EER27476.1 - 0.041 13.5 0.1 0.14 11.8 0.1 1.9 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain ORC5_C PF14630.1 EER27477.1 - 1e-87 294.0 0.0 1.6e-87 293.3 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EER27477.1 - 2.6e-16 60.1 0.0 8.1e-16 58.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EER27477.1 - 0.00051 19.9 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EER27477.1 - 0.00094 18.8 0.0 0.0099 15.5 0.0 2.4 1 1 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EER27477.1 - 0.0023 17.0 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EER27477.1 - 0.0056 16.8 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EER27477.1 - 0.0097 15.6 0.0 0.048 13.3 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 EER27477.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.9 EER27477.1 - 0.014 14.3 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF815 PF05673.8 EER27477.1 - 0.025 13.5 0.0 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 EER27477.1 - 0.026 15.3 0.0 0.063 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EER27477.1 - 0.044 13.9 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 EER27477.1 - 0.077 13.1 0.0 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EER27477.1 - 0.11 12.5 0.0 0.49 10.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 EER27477.1 - 0.16 11.9 0.0 0.69 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PUF PF00806.14 EER27478.1 - 8.5e-58 188.7 5.1 1.3e-07 30.6 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DnaB_bind PF10410.4 EER27478.1 - 0.017 15.1 0.1 8.6 6.4 0.0 2.9 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase TylF PF05711.6 EER27478.1 - 0.23 10.5 0.0 0.44 9.5 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) RNA_pol_Rpb2_6 PF00562.23 EER27479.1 - 2.6e-117 391.8 0.0 3.8e-117 391.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EER27479.1 - 7.6e-54 181.7 0.7 1.6e-53 180.6 0.2 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EER27479.1 - 1.2e-29 103.0 1.6 3e-29 101.7 0.9 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EER27479.1 - 2.5e-28 98.1 0.3 2.6e-27 94.9 0.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EER27479.1 - 1.8e-23 82.0 0.3 5.4e-23 80.5 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EER27479.1 - 3.3e-20 71.6 0.0 7.5e-20 70.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EER27479.1 - 2.2e-13 49.9 0.7 4.9e-13 48.8 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 EER27479.1 - 0.042 12.1 1.4 0.044 12.1 0.1 1.6 2 0 0 2 2 2 0 Baculovirus Y142 protein Glycos_transf_1 PF00534.15 EER27481.1 - 2.8e-20 72.4 0.0 6.5e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EER27481.1 - 2.9e-09 37.1 0.0 1.4e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EER27481.1 - 0.0001 22.5 0.0 0.00024 21.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 E1-E2_ATPase PF00122.15 EER27482.1 - 3.2e-62 209.5 7.9 8e-62 208.2 5.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EER27482.1 - 8.5e-23 81.8 0.0 2.9e-22 80.1 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EER27482.1 - 1.2e-12 48.3 0.0 2.9e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EER27482.1 - 2.8e-11 42.7 0.0 6.5e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EER27482.1 - 0.0014 18.2 0.1 0.003 17.1 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER27482.1 - 0.022 14.7 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit RRM_1 PF00076.17 EER27483.1 - 1.2e-06 28.0 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER27483.1 - 1.8e-05 24.5 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER27483.1 - 0.00017 21.5 0.0 0.00037 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EER27483.1 - 0.00027 21.1 0.0 0.0009 19.4 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. PAT1 PF09770.4 EER27483.1 - 0.91 7.6 34.3 1.3 7.1 23.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Citrate_synt PF00285.16 EER27484.1 - 3.2e-100 335.3 0.0 3.8e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Mito_carr PF00153.22 EER27485.1 - 6.8e-26 89.8 6.0 1.3e-11 44.0 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein PT-TG PF14449.1 EER27485.1 - 0.39 10.5 0.0 0.39 10.5 0.0 2.7 4 0 0 4 4 4 0 Pre-toxin TG Peptidase_M16 PF00675.15 EER27486.1 - 4.1e-20 72.0 0.0 1.1e-19 70.7 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EER27486.1 - 2.2e-14 53.5 0.1 7.6e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 EER27487.1 - 1e-37 130.0 0.0 5.9e-33 114.4 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EER27487.1 - 3e-20 71.8 3.2 1.6e-15 56.7 0.1 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EER27487.1 - 1.2e-09 37.6 0.3 6.1e-05 22.4 0.0 2.8 3 0 0 3 3 3 2 TFIIE alpha subunit MarR_2 PF12802.2 EER27487.1 - 0.041 13.5 0.2 14 5.4 0.0 3.6 4 0 0 4 4 4 0 MarR family Pga1 PF10333.4 EER27488.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator PAP2 PF01569.16 EER27488.1 - 0.084 12.5 0.2 0.084 12.5 0.1 1.8 2 0 0 2 2 2 0 PAP2 superfamily Tubulin PF00091.20 EER27489.1 - 6.8e-70 235.2 0.0 9.1e-70 234.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EER27489.1 - 1.5e-48 163.9 0.0 3.1e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EER27489.1 - 0.0034 16.8 0.0 0.0065 15.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.2 EER27490.1 - 2.8e-39 133.0 0.0 3.7e-15 55.5 0.0 3.9 4 0 0 4 4 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EER27490.1 - 1.1e-11 44.7 0.2 2.6e-06 27.4 0.3 3.9 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EER27490.1 - 7e-09 34.3 0.3 0.00096 18.2 0.0 4.9 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 EER27490.1 - 3.5e-06 26.5 0.1 0.0012 18.3 0.1 3.8 3 1 1 4 4 4 1 EF-hand domain pair UBA PF00627.26 EER27490.1 - 0.00019 21.1 0.0 0.0004 20.1 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_6 PF13405.1 EER27490.1 - 0.003 17.3 4.2 3.8 7.6 0.0 5.2 5 0 0 5 5 5 1 EF-hand domain DUF812 PF05667.6 EER27490.1 - 0.0032 16.0 20.5 0.0084 14.6 14.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF812) GAS PF13851.1 EER27490.1 - 0.039 13.1 27.8 0.1 11.7 16.2 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 EER27490.1 - 0.042 11.1 24.4 0.06 10.6 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF960 PF06124.6 EER27490.1 - 0.12 12.5 0.0 29 5.0 0.0 3.1 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) Myosin_tail_1 PF01576.14 EER27490.1 - 0.19 9.3 33.7 0.83 7.2 23.5 1.7 1 1 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.4 EER27490.1 - 0.31 10.8 30.1 0.48 10.2 6.9 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 EER27490.1 - 1.4 7.4 26.5 0.29 9.7 6.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 EER27490.1 - 2 8.3 33.9 1.7 8.5 5.8 4.3 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EER27490.1 - 2.7 7.5 30.5 1.8 8.0 12.8 2.3 1 1 1 2 2 2 0 IncA protein WEMBL PF05701.6 EER27490.1 - 3.2 6.1 30.5 33 2.7 20.9 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 EER27490.1 - 3.8 7.2 31.4 17 5.1 4.9 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EER27490.1 - 4.6 7.0 30.2 7.7 6.2 11.2 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MARVEL PF01284.18 EER27491.1 - 2e-20 73.0 14.5 2.7e-20 72.6 10.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1360 PF07098.6 EER27491.1 - 2.3 8.0 5.3 0.86 9.3 1.4 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1360) Cys_Met_Meta_PP PF01053.15 EER27492.1 - 1.2e-151 504.4 0.0 1.3e-151 504.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EER27492.1 - 2.7e-14 53.0 0.2 4.7e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EER27492.1 - 4.3e-09 35.7 0.1 9.1e-09 34.7 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EER27492.1 - 1.3e-07 30.7 0.2 2.5e-07 29.7 0.2 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EER27492.1 - 2.9e-05 23.3 0.0 5.8e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 EER27492.1 - 0.017 13.8 0.0 0.026 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EER27492.1 - 0.024 12.9 0.1 0.032 12.5 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase SelA PF03841.8 EER27492.1 - 0.025 13.3 0.1 0.082 11.6 0.1 1.7 1 1 0 1 1 1 0 L-seryl-tRNA selenium transferase SLA_LP_auto_ag PF05889.8 EER27492.1 - 0.054 11.9 0.0 0.081 11.3 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) AMP-binding PF00501.23 EER27493.1 - 9e-78 261.5 0.0 1.1e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF2012 PF09430.5 EER27494.1 - 1.2e-29 102.6 0.0 1.7e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) WW PF00397.21 EER27495.1 - 5e-07 29.4 4.4 8.8e-07 28.6 3.1 1.4 1 0 0 1 1 1 1 WW domain CCDC50_N PF15295.1 EER27495.1 - 0.017 15.0 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus LAP1C PF05609.7 EER27495.1 - 0.47 9.0 3.5 0.59 8.7 2.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Ank PF00023.25 EER27496.1 - 1e-102 331.2 0.0 1.5e-10 40.3 0.0 11.9 11 0 0 11 11 11 10 Ankyrin repeat Ank_2 PF12796.2 EER27496.1 - 1.2e-92 304.3 4.7 3.1e-19 69.0 0.0 6.5 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EER27496.1 - 2e-77 247.2 0.0 2.5e-06 27.1 0.0 12.0 12 0 0 12 12 11 10 Ankyrin repeat Ank_4 PF13637.1 EER27496.1 - 3.3e-70 231.3 0.0 2.9e-13 49.9 0.0 7.6 3 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER27496.1 - 6e-59 194.7 7.3 2.1e-09 37.3 0.1 10.0 1 1 10 11 11 11 10 Ankyrin repeats (many copies) SIR2_2 PF13289.1 EER27496.1 - 5.4e-20 71.7 0.1 1.5e-19 70.3 0.1 1.8 1 0 0 1 1 1 1 SIR2-like domain Shigella_OspC PF06128.6 EER27496.1 - 2.6e-10 40.2 6.8 0.39 10.1 0.1 6.6 2 2 5 7 7 7 4 Shigella flexneri OspC protein HTH_22 PF13309.1 EER27496.1 - 2.9e-05 23.7 3.4 24 4.7 0.0 6.6 6 1 0 6 6 6 0 HTH domain Sod_Fe_C PF02777.13 EER27496.1 - 0.00043 20.0 5.4 2.1 8.2 0.0 5.3 2 1 3 5 5 5 1 Iron/manganese superoxide dismutases, C-terminal domain RraB PF06877.6 EER27496.1 - 0.0044 17.6 3.8 46 4.7 0.0 4.8 2 2 2 4 4 4 0 Regulator of ribonuclease activity B ScdA_N PF04405.9 EER27496.1 - 0.016 14.6 0.0 9 5.7 0.0 4.0 5 0 0 5 5 4 0 Domain of Unknown function (DUF542) FATC PF02260.15 EER27496.1 - 0.017 14.5 0.1 64 3.1 0.0 5.2 6 0 0 6 6 6 0 FATC domain CholecysA-Rec_N PF09193.5 EER27496.1 - 0.044 13.6 1.2 85 3.1 0.0 5.2 5 0 0 5 5 5 0 Cholecystokinin A receptor, N-terminal Erp_C PF06780.6 EER27496.1 - 0.062 13.1 5.1 11 5.8 0.1 4.1 3 1 1 4 4 4 0 Erp protein C-terminus Gp-FAR-1 PF05823.7 EER27496.1 - 0.089 12.7 3.7 3.2 7.6 0.1 2.9 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fer4_14 PF13394.1 EER27496.1 - 0.17 11.9 1.4 1.3e+02 2.5 0.0 4.5 2 1 3 5 5 5 0 4Fe-4S single cluster domain DUF1771 PF08590.5 EER27496.1 - 0.38 10.8 1.8 31 4.6 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1771) SRI PF08236.6 EER27496.1 - 0.8 9.6 4.6 20 5.1 0.4 3.9 3 1 0 4 4 3 0 SRI (Set2 Rpb1 interacting) domain FliT PF05400.8 EER27496.1 - 2.4 8.6 18.1 3.2 8.2 0.6 5.6 1 1 4 6 6 6 0 Flagellar protein FliT Spore_SspJ PF09575.5 EER27496.1 - 2.9 8.1 21.2 1.1 9.4 0.1 7.5 8 4 3 11 11 10 0 Small spore protein J (Spore_SspJ) WD40 PF00400.27 EER27497.1 - 1e-12 47.4 13.2 2.5e-05 23.9 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat Mito_carr PF00153.22 EER27498.1 - 3.1e-54 180.6 0.3 1.3e-17 63.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EER27498.1 - 0.00078 19.2 0.2 0.0019 18.0 0.2 1.7 1 0 0 1 1 1 1 UcrQ family ATP_synt_I PF03899.10 EER27498.1 - 0.0038 17.3 5.5 0.42 10.8 0.0 3.6 2 1 1 3 3 3 1 ATP synthase I chain Ras PF00071.17 EER27499.1 - 6.2e-66 220.7 0.5 7.2e-66 220.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER27499.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER27499.1 - 1.4e-16 60.1 0.1 1.7e-16 59.9 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER27499.1 - 1.5e-05 24.3 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EER27499.1 - 3.7e-05 23.2 0.1 7.6e-05 22.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EER27499.1 - 6.4e-05 22.8 0.0 9.1e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EER27499.1 - 0.00035 20.7 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EER27499.1 - 0.00066 18.9 0.0 0.00094 18.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EER27499.1 - 0.0013 18.8 0.0 0.0025 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EER27499.1 - 0.0026 17.0 0.0 0.018 14.3 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EER27499.1 - 0.01 15.0 0.0 0.027 13.6 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EER27499.1 - 0.02 14.8 0.1 0.064 13.2 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain Septin PF00735.13 EER27499.1 - 0.028 13.4 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EER27499.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EER27499.1 - 0.044 13.6 0.2 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EER27499.1 - 0.053 13.8 0.1 0.12 12.6 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EER27499.1 - 0.055 13.1 0.0 0.11 12.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EER27499.1 - 0.082 12.3 0.1 0.93 8.9 0.0 2.3 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Peptidase_M1 PF01433.15 EER27500.1 - 9.6e-128 426.5 0.1 1.6e-127 425.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EER27500.1 - 1e-77 261.5 0.0 1.6e-77 260.9 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EER27500.1 - 6.1e-22 78.0 1.9 1.1e-21 77.1 1.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Ssl1 PF04056.9 EER27501.1 - 3.8e-75 251.7 0.0 5e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EER27501.1 - 3e-18 65.5 7.1 3e-18 65.5 5.0 2.3 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EER27501.1 - 1.2e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DZR PF12773.2 EER27501.1 - 0.84 9.5 20.2 0.57 10.0 3.4 3.3 2 1 0 2 2 2 0 Double zinc ribbon Abhydrolase_5 PF12695.2 EER27502.1 - 9.1e-07 28.7 0.5 1.9e-06 27.6 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER27502.1 - 3.8e-05 23.6 4.1 0.00031 20.7 2.2 2.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER27502.1 - 6e-05 22.3 0.3 0.00011 21.4 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EER27502.1 - 0.0021 17.5 0.2 0.0044 16.4 0.1 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EER27502.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PUF PF00806.14 EER27503.1 - 4.9e-35 117.0 1.1 5.9e-06 25.4 0.0 9.4 10 0 0 10 10 10 7 Pumilio-family RNA binding repeat TPT PF03151.11 EER27505.1 - 1.5e-35 122.0 3.0 1.5e-35 122.0 2.1 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EER27505.1 - 2.6e-06 26.5 12.7 0.0065 15.4 0.2 2.3 2 0 0 2 2 2 2 UAA transporter family PSII PF00421.14 EER27505.1 - 0.0029 16.2 1.3 0.0049 15.5 0.9 1.2 1 0 0 1 1 1 1 Photosystem II protein EamA PF00892.15 EER27505.1 - 0.013 15.5 32.1 0.098 12.7 7.9 3.4 3 2 0 3 3 3 0 EamA-like transporter family CRT-like PF08627.5 EER27505.1 - 0.12 12.3 0.1 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 CRT-like Multi_Drug_Res PF00893.14 EER27505.1 - 7.6 7.0 11.6 0.61 10.5 0.7 3.6 2 1 2 4 4 4 0 Small Multidrug Resistance protein RVT_2 PF07727.9 EER27506.1 - 6.1e-69 231.7 0.0 1.9e-68 230.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EER27506.1 - 3.5e-19 69.0 0.0 1.9e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EER27506.1 - 3.1e-06 26.7 0.1 7.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EER27506.1 - 1.2e-05 25.0 2.3 2.3e-05 24.0 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Phage_Gp23 PF10669.4 EER27506.1 - 1.4 9.0 11.1 0.1 12.7 2.6 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Molybdopterin PF00384.17 EER27507.1 - 1.2e-73 248.3 0.0 1.8e-36 125.8 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 EER27507.1 - 4.3e-19 67.4 0.1 1.1e-18 66.1 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EER27507.1 - 6.2e-15 55.0 0.0 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer4 PF00037.22 EER27507.1 - 0.098 12.2 1.1 2.7 7.7 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EER27507.1 - 0.17 11.6 2.3 3.3 7.6 1.6 2.5 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_6 PF12837.2 EER27507.1 - 0.4 10.6 3.3 0.4 10.6 0.9 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain XRCC4 PF06632.7 EER27508.1 - 3.7e-05 22.7 15.9 3.7e-05 22.7 11.0 2.5 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Matrilin_ccoil PF10393.4 EER27508.1 - 0.018 14.3 2.1 2.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1009 PF06230.6 EER27508.1 - 0.069 12.4 1.0 0.42 9.9 0.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1009) DUF1848 PF08902.6 EER27508.1 - 0.19 11.2 0.4 0.26 10.7 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) FUSC PF04632.7 EER27508.1 - 0.34 9.3 2.0 0.25 9.7 0.4 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family ER_lumen_recept PF00810.13 EER27512.1 - 1.7e-56 190.7 9.5 2.5e-56 190.2 6.6 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF1761 PF08570.5 EER27512.1 - 0.024 14.6 1.6 0.34 10.9 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) PQ-loop PF04193.9 EER27512.1 - 0.25 10.9 14.7 1.5 8.4 0.1 3.7 4 0 0 4 4 4 0 PQ loop repeat UPF0561 PF10573.4 EER27513.1 - 4 7.3 5.8 6.5 6.6 2.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0561 DUF382 PF04037.8 EER27514.1 - 1.8e-62 208.8 2.1 4.2e-62 207.6 1.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EER27514.1 - 2e-21 75.0 7.6 5.5e-21 73.6 5.3 1.8 1 0 0 1 1 1 1 PSP MRP-S33 PF08293.6 EER27515.1 - 9.2e-33 112.0 0.1 1.2e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 DUF866 PF05907.8 EER27515.1 - 0.07 12.6 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Ribonuclease_3 PF00636.21 EER27516.1 - 1.7e-16 60.6 0.4 5.1e-15 55.9 0.0 2.9 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EER27516.1 - 1.5e-10 41.1 0.0 3.5e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EER27516.1 - 0.0084 16.6 0.0 0.023 15.2 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif GPI-anchored PF10342.4 EER27517.1 - 3.4e-17 62.6 0.1 4.3e-17 62.3 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CDC45 PF02724.9 EER27517.1 - 0.07 11.1 5.8 0.076 11.0 4.0 1.0 1 0 0 1 1 1 0 CDC45-like protein ECH PF00378.15 EER27518.1 - 2.4e-44 151.3 0.0 3.2e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family RTA1 PF04479.8 EER27519.1 - 5.1e-23 81.7 1.2 7e-23 81.2 0.8 1.2 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.7 EER27519.1 - 1.3 8.7 11.3 4.6 7.0 1.4 3.0 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Sigma70_ner PF04546.8 EER27520.1 - 0.055 13.0 0.3 0.068 12.7 0.2 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF4611 PF15387.1 EER27520.1 - 0.55 10.4 4.2 0.85 9.8 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Abhydrolase_6 PF12697.2 EER27521.1 - 6.8e-33 114.4 0.0 8.8e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27521.1 - 3.9e-16 59.1 0.0 2.1e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER27521.1 - 4.8e-16 59.0 0.1 1.8e-15 57.1 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EER27521.1 - 7.2e-09 35.5 0.0 9.7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EER27521.1 - 0.0001 22.0 0.0 0.00018 21.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EER27521.1 - 0.00045 19.7 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydro_lipase PF04083.11 EER27521.1 - 0.0011 18.2 0.2 0.0075 15.5 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Thioesterase PF00975.15 EER27521.1 - 0.0013 18.9 0.0 0.0018 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.6 EER27521.1 - 0.0032 16.3 0.0 0.0076 15.0 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase UPF0227 PF05728.7 EER27521.1 - 0.0095 15.6 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 EER27521.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EER27521.1 - 0.016 14.6 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 EER27521.1 - 0.019 13.8 0.0 0.19 10.6 0.0 2.0 2 0 0 2 2 2 0 Chlorophyllase enzyme LCAT PF02450.10 EER27521.1 - 0.02 13.8 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EER27521.1 - 0.081 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Ser_hydrolase PF06821.8 EER27521.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Lipase_3 PF01764.20 EER27521.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Ribosomal_S3Ae PF01015.13 EER27522.1 - 1.4e-77 259.4 7.3 1.7e-77 259.1 5.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family mRNA_cap_C PF03919.10 EER27522.1 - 0.11 12.8 0.2 0.25 11.6 0.0 1.8 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain GTP_CH_N PF12471.3 EER27523.1 - 3.1e-92 307.5 0.0 4.9e-92 306.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EER27523.1 - 6.5e-15 54.7 0.0 1.3e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 GTP cyclohydrolase II GntR PF00392.16 EER27523.1 - 0.047 13.1 0.0 53 3.3 0.0 3.5 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family UPRTase PF14681.1 EER27524.1 - 7e-79 263.8 0.0 8.7e-79 263.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EER27524.1 - 0.0004 20.1 0.0 0.00065 19.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EER27524.1 - 0.049 13.3 0.1 0.089 12.5 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) WAPL PF07814.8 EER27525.1 - 7.7e-29 100.5 1.5 1.2e-28 99.8 1.0 1.2 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Ras PF00071.17 EER27526.1 - 3.7e-47 159.7 0.1 4.2e-47 159.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER27526.1 - 4.8e-17 62.5 0.0 6.6e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER27526.1 - 1.1e-06 28.0 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EER27526.1 - 3.2e-06 27.0 0.0 5.7e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER27526.1 - 1.8e-05 24.2 0.0 0.0004 19.8 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EER27526.1 - 0.0038 16.4 0.0 0.0059 15.8 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EER27526.1 - 0.073 12.3 0.1 0.16 11.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 EER27526.1 - 0.11 12.2 0.1 0.29 10.8 0.0 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B tRNA-synt_2b PF00587.20 EER27527.1 - 4.6e-32 110.9 0.0 7.2e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EER27527.1 - 2e-18 66.3 9.0 2e-18 66.3 6.3 2.4 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain ICL PF00463.16 EER27527.1 - 0.0057 14.9 2.0 0.011 14.0 1.4 1.3 1 0 0 1 1 1 1 Isocitrate lyase family 2-Hacid_dh_C PF02826.14 EER27528.1 - 2.8e-52 176.4 0.0 4.6e-52 175.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER27528.1 - 3.1e-37 127.0 0.0 4.3e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EER27528.1 - 2.7e-06 27.3 2.2 3.2e-06 27.0 0.3 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EER27528.1 - 3.7e-05 23.1 0.1 9.3e-05 21.8 0.0 1.7 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.16 EER27528.1 - 0.00055 19.8 0.1 0.0014 18.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EER27528.1 - 0.007 15.7 0.3 0.05 12.9 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EER27528.1 - 0.017 14.8 2.2 1.3 8.6 0.5 3.0 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EER27528.1 - 0.091 13.0 0.1 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain Pkinase PF00069.20 EER27529.1 - 4.8e-55 186.5 0.0 2.2e-53 181.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27529.1 - 5.3e-20 71.5 0.0 3.9e-18 65.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase P5-ATPase PF12409.3 EER27530.1 - 1.9e-36 124.4 0.0 3.9e-36 123.4 0.0 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 EER27530.1 - 1.1e-28 99.8 0.0 3.2e-28 98.3 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EER27530.1 - 1.9e-24 86.8 0.0 5.5e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EER27530.1 - 2.4e-12 47.7 0.0 4.8e-11 43.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EER27530.1 - 3.3e-07 29.9 4.8 3.3e-07 29.9 3.3 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EER27530.1 - 0.00025 20.9 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EER27530.1 - 0.00088 18.6 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EER27530.1 - 0.0073 15.9 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NAP PF00956.13 EER27531.1 - 2.1e-86 288.9 11.2 2.1e-86 288.9 7.8 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Myosin_head PF00063.16 EER27532.1 - 2.7e-245 815.6 0.7 4.9e-245 814.8 0.5 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EER27532.1 - 1.1e-34 118.3 3.6 3e-34 117.0 2.5 1.8 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EER27532.1 - 3.5e-13 47.8 29.2 9.2e-05 21.7 0.9 6.7 6 0 0 6 6 6 4 IQ calmodulin-binding motif DUF869 PF05911.6 EER27532.1 - 0.00036 18.9 9.6 0.00066 18.0 6.7 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) AAA_16 PF13191.1 EER27532.1 - 0.003 17.5 2.3 0.047 13.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EER27532.1 - 0.0038 17.3 3.3 0.0068 16.5 0.1 3.1 2 1 1 3 3 3 1 AAA domain AAA_10 PF12846.2 EER27532.1 - 0.0044 16.4 1.3 0.028 13.8 0.0 2.8 3 1 0 3 3 3 1 AAA-like domain Baculo_PEP_C PF04513.7 EER27532.1 - 0.017 14.9 6.6 0.09 12.6 4.6 2.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_N PF02736.14 EER27532.1 - 0.023 14.3 2.1 0.051 13.2 1.4 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain TMP_2 PF06791.8 EER27532.1 - 0.024 14.2 2.9 0.057 13.0 2.0 1.6 1 0 0 1 1 1 0 Prophage tail length tape measure protein AAA_19 PF13245.1 EER27532.1 - 0.025 14.3 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain GAS PF13851.1 EER27532.1 - 0.062 12.4 24.5 0.029 13.5 9.6 2.7 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EER27532.1 - 0.11 11.6 1.3 0.2 10.7 0.9 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Cortex-I_coil PF09304.5 EER27532.1 - 0.73 9.9 24.6 0.2 11.6 5.2 3.3 2 1 1 3 3 3 0 Cortexillin I, coiled coil FUSC PF04632.7 EER27532.1 - 0.9 7.8 5.9 1.6 7.0 4.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.5 EER27532.1 - 4.1 7.5 15.6 5.4 7.1 3.6 3.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Tropomyosin_1 PF12718.2 EER27532.1 - 5.8 6.7 25.8 1.6 8.5 12.4 2.6 1 1 1 2 2 2 0 Tropomyosin like FlaC_arch PF05377.6 EER27532.1 - 7.6 6.5 9.6 1.6 8.7 0.1 3.9 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 EER27532.1 - 8.5 5.3 25.6 6.7 5.6 5.1 2.6 1 1 1 2 2 2 0 Autophagy protein Apg6 Ham1p_like PF01725.11 EER27533.1 - 4.4e-53 179.4 0.0 4.9e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EER27534.1 - 2.7e-27 95.6 0.1 5.9e-27 94.5 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EER27534.1 - 1.1e-13 51.9 0.8 3.1e-13 50.5 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EER27534.1 - 8.6e-05 22.7 0.0 0.00035 20.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EER27534.1 - 0.0007 19.5 0.4 0.00081 19.3 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER27534.1 - 0.0011 18.8 0.0 0.004 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 EER27534.1 - 0.0025 17.7 0.1 0.011 15.6 0.1 2.1 1 1 0 1 1 1 1 Adenylate kinase Cytidylate_kin2 PF13189.1 EER27534.1 - 0.0056 16.6 0.0 0.0094 15.8 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_22 PF13401.1 EER27534.1 - 0.0061 16.7 0.0 0.012 15.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EER27534.1 - 0.0065 16.3 0.0 0.022 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EER27534.1 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase KTI12 PF08433.5 EER27534.1 - 0.0093 15.1 0.0 0.024 13.8 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NTPase_1 PF03266.10 EER27534.1 - 0.014 15.1 0.3 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.1 EER27534.1 - 0.031 14.2 0.0 0.068 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.2 EER27534.1 - 0.034 13.5 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EER27534.1 - 0.05 13.0 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.13 EER27534.1 - 0.099 12.1 0.1 0.18 11.2 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EER27534.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Stn1_C PF12659.2 EER27534.1 - 0.14 11.9 0.0 12 5.7 0.0 2.1 1 1 1 2 2 2 0 Telomere capping C-terminal wHTH AAA_3 PF07726.6 EER27534.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Peptidase_C78 PF07910.8 EER27535.1 - 1.6e-65 220.3 0.0 2.1e-65 219.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EER27535.1 - 0.0039 17.2 3.8 0.19 11.9 1.0 2.4 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding PSP PF04046.11 EER27535.1 - 0.057 12.8 0.4 0.27 10.6 0.0 2.3 3 0 0 3 3 3 0 PSP AA_kinase PF00696.23 EER27536.1 - 5.5e-41 140.6 0.2 1.5e-40 139.3 0.1 1.7 2 0 0 2 2 2 1 Amino acid kinase family ACT_7 PF13840.1 EER27536.1 - 3.7e-13 48.8 1.1 3.9e-11 42.3 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EER27536.1 - 1.7e-12 46.5 0.5 1.5e-10 40.3 0.1 2.6 2 0 0 2 2 2 2 ACT domain zf-Tim10_DDP PF02953.10 EER27537.1 - 2.4e-22 78.0 1.4 2.8e-22 77.7 1.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger G10 PF01125.12 EER27538.1 - 4.6e-67 224.0 5.5 5.1e-67 223.9 3.8 1.0 1 0 0 1 1 1 1 G10 protein DNA_RNApol_7kD PF03604.8 EER27538.1 - 1.1 8.7 8.5 3.3 7.2 5.9 1.9 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Fork_head PF00250.13 EER27539.1 - 4.4e-35 119.6 0.1 1e-34 118.3 0.1 1.6 1 0 0 1 1 1 1 Fork head domain Ribosomal_L23eN PF03939.8 EER27540.1 - 4.8e-22 77.7 10.6 4.8e-22 77.7 7.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EER27540.1 - 8e-17 60.9 2.2 8e-17 60.9 1.5 2.0 2 0 0 2 2 2 1 Ribosomal protein L23 PHA-1 PF06542.6 EER27540.1 - 0.033 12.9 1.0 0.045 12.4 0.7 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 P2 PF07194.6 EER27540.1 - 0.078 12.8 0.3 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 P2 response regulator binding domain DUF3321 PF11968.3 EER27541.1 - 1e-90 303.2 0.0 1.2e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EER27541.1 - 0.00097 18.8 0.0 0.0019 17.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain eRF1_2 PF03464.10 EER27542.1 - 1.3e-45 155.0 0.1 2.2e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EER27542.1 - 1.4e-39 134.8 0.4 3e-39 133.7 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EER27542.1 - 3.1e-28 97.9 0.0 5.2e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EER27542.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PDT PF00800.13 EER27543.1 - 3e-65 219.1 0.0 3.7e-65 218.8 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EER27543.1 - 0.021 14.2 0.0 0.083 12.3 0.0 2.0 2 0 0 2 2 2 0 ACT domain MaoC_dehydratas PF01575.14 EER27544.1 - 9.6e-05 21.7 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain DKCLD PF08068.7 EER27545.1 - 6.2e-30 102.9 0.8 3.7e-29 100.4 0.0 2.6 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.13 EER27545.1 - 3e-24 85.8 0.2 2e-21 76.7 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EER27545.1 - 2.8e-21 75.0 1.7 5e-21 74.2 1.1 1.4 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 EER27545.1 - 6.7 6.3 30.0 10 5.7 20.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EER27545.1 - 8.3 5.5 15.0 12 4.9 10.4 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CLTH PF10607.4 EER27546.1 - 4.3e-34 117.2 0.1 7.6e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain DUF1875 PF08961.5 EER27546.1 - 0.01 15.1 0.2 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) TPR_4 PF07721.9 EER27546.1 - 0.58 10.7 3.1 1e+02 3.7 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2431 PF10354.4 EER27547.1 - 1.4e-42 145.4 0.0 5.6e-29 101.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) TPT PF03151.11 EER27548.1 - 1.8e-12 47.1 7.2 1.8e-12 47.1 5.0 2.7 2 2 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EER27548.1 - 9.1e-12 44.4 21.4 1.1e-11 44.1 14.8 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EER27548.1 - 0.00098 19.1 6.1 0.00098 19.1 4.2 2.4 2 0 0 2 2 2 1 EamA-like transporter family PHO4 PF01384.15 EER27548.1 - 0.0031 16.2 5.8 0.0031 16.2 4.0 2.5 1 1 1 2 2 2 1 Phosphate transporter family Nol1_Nop2_Fmu PF01189.12 EER27549.1 - 1.1e-95 320.2 0.0 1.5e-95 319.7 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 EER27549.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.11 EER27549.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Blt1 PF12754.2 EER27550.1 - 1.7e-61 208.5 0.1 5.6e-61 206.8 0.1 1.7 1 1 0 1 1 1 1 Cell-cycle control medial ring component Striatin PF08232.7 EER27551.1 - 6.8e-43 146.2 0.8 1.4e-42 145.1 0.6 1.6 1 0 0 1 1 1 1 Striatin family WD40 PF00400.27 EER27551.1 - 1.6e-34 116.5 15.8 1.9e-07 30.7 0.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EER27551.1 - 0.075 11.3 0.0 0.15 10.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain eIF2A PF08662.6 EER27551.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A XPA_C PF05181.7 EER27552.1 - 8.7e-29 98.8 3.1 8.7e-29 98.8 2.1 1.8 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 EER27552.1 - 0.00021 20.9 7.8 0.00021 20.9 5.4 1.9 2 0 0 2 2 2 1 XPA protein N-terminal YhfH PF14149.1 EER27552.1 - 0.052 13.3 10.2 0.32 10.8 0.3 2.6 2 0 0 2 2 2 0 YhfH-like protein ArfGap PF01412.13 EER27552.1 - 0.24 11.2 5.5 0.94 9.2 2.1 2.6 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf PIG-P PF08510.7 EER27553.1 - 2.9e-43 146.5 2.2 3e-43 146.4 0.3 1.9 2 0 0 2 2 2 1 PIG-P CDC45 PF02724.9 EER27553.1 - 0.12 10.4 0.0 0.18 9.8 0.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.10 EER27553.1 - 0.13 11.5 1.8 0.096 11.9 0.2 1.4 1 1 0 1 1 1 0 Ras-mediated vulval-induction antagonist Nop14 PF04147.7 EER27553.1 - 0.23 9.3 4.3 0.26 9.1 2.9 1.1 1 0 0 1 1 1 0 Nop14-like family MORN PF02493.15 EER27554.1 - 3.2e-14 51.7 23.4 0.0015 18.1 0.2 4.6 4 0 0 4 4 4 4 MORN repeat UCH PF00443.24 EER27554.1 - 3.5e-12 45.9 0.0 5.2e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.1 EER27554.1 - 7.5e-11 41.5 11.3 1.2e-10 40.9 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) MATH PF00917.21 EER27554.1 - 7.2e-07 29.4 0.0 0.0034 17.6 0.1 2.5 2 0 0 2 2 2 2 MATH domain USP7_ICP0_bdg PF12436.3 EER27554.1 - 0.00062 19.0 0.0 0.0015 17.8 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 zf-C3HC4_2 PF13923.1 EER27554.1 - 0.0026 17.7 13.6 0.0043 17.0 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TRAP_beta PF05753.9 EER27554.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein beta (TRAPB) zf-RING_5 PF14634.1 EER27554.1 - 0.18 11.5 12.6 0.31 10.7 8.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.12 EER27555.1 - 1.8e-145 483.7 0.0 2e-145 483.4 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Myb_DNA-binding PF00249.26 EER27556.1 - 5.8e-14 51.8 0.0 1e-08 35.0 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER27556.1 - 0.00013 21.9 0.2 0.18 11.9 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain DUF544 PF04424.8 EER27557.1 - 1.2e-11 44.4 0.0 2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Gcd10p PF04189.8 EER27558.1 - 4.5e-92 308.3 0.0 5.8e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Shugoshin_N PF07558.6 EER27558.1 - 0.029 14.0 0.1 0.074 12.7 0.1 1.6 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF872 PF05915.7 EER27559.1 - 0.2 11.5 2.0 5.7 6.8 0.0 3.6 3 1 1 4 4 4 0 Eukaryotic protein of unknown function (DUF872) P21-Arc PF04062.9 EER27560.1 - 1.6e-80 268.9 0.0 1.8e-80 268.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit AAA PF00004.24 EER27561.1 - 1.5e-15 57.5 0.5 3e-15 56.5 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EER27561.1 - 2.7e-14 52.8 0.0 6.9e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EER27561.1 - 1.5e-13 50.7 0.0 4.9e-13 49.0 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EER27561.1 - 1.4e-10 40.5 0.0 3.6e-08 32.5 0.0 2.6 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EER27561.1 - 1.5e-07 31.6 0.2 2.4e-06 27.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 EER27561.1 - 9.3e-07 28.5 0.0 1.8e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 EER27561.1 - 9.8e-07 28.0 0.2 1.3e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EER27561.1 - 2.3e-06 27.6 0.6 0.00074 19.5 0.0 3.2 2 2 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EER27561.1 - 6.4e-06 25.1 0.1 0.046 12.4 0.1 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_30 PF13604.1 EER27561.1 - 7.7e-06 25.6 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER27561.1 - 8.4e-06 25.4 0.0 2.2e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EER27561.1 - 3.9e-05 23.3 0.1 0.00011 21.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EER27561.1 - 0.00013 20.9 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EER27561.1 - 0.00017 21.3 0.2 0.0012 18.5 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EER27561.1 - 0.00026 20.8 0.0 0.00064 19.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EER27561.1 - 0.00029 20.4 0.2 0.0026 17.3 0.1 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EER27561.1 - 0.0012 18.1 0.3 0.35 10.0 0.0 2.4 1 1 1 2 2 2 1 PhoH-like protein AAA_24 PF13479.1 EER27561.1 - 0.002 17.7 0.2 0.0041 16.7 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EER27561.1 - 0.0062 15.9 0.5 0.024 14.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EER27561.1 - 0.009 15.9 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EER27561.1 - 0.0094 15.4 0.0 0.35 10.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EER27561.1 - 0.01 15.2 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EER27561.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase DEAD PF00270.24 EER27561.1 - 0.013 14.9 0.0 0.27 10.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.10 EER27561.1 - 0.016 15.0 0.0 0.42 10.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EER27561.1 - 0.021 13.8 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EER27561.1 - 0.022 14.2 0.2 1.2 8.4 0.2 2.4 1 1 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EER27561.1 - 0.031 15.0 0.0 0.07 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EER27561.1 - 0.033 14.4 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EER27561.1 - 0.054 12.6 0.1 0.17 11.0 0.0 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI MiaE PF06175.6 EER27561.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) RNA_helicase PF00910.17 EER27561.1 - 0.084 13.0 0.0 0.22 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase His_Phos_2 PF00328.17 EER27562.1 - 7.7e-15 55.0 0.0 5.1e-13 49.0 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Metallophos PF00149.23 EER27563.1 - 0.00023 20.6 1.5 0.0009 18.6 1.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER27563.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pro_isomerase PF00160.16 EER27564.1 - 1.1e-36 126.3 0.0 2.6e-36 125.1 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD R3H PF01424.17 EER27565.1 - 4.2e-12 45.5 0.1 4.2e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 R3H domain RRM_6 PF14259.1 EER27565.1 - 3.5e-06 26.9 0.1 6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER27565.1 - 1.6e-05 24.4 0.1 3e-05 23.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER27565.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.2 EER27565.1 - 0.1 12.2 7.2 0.074 12.6 2.2 2.8 2 0 0 2 2 2 0 SUZ-C motif Aldo_ket_red PF00248.16 EER27566.1 - 1.5e-24 86.3 0.0 3.4e-24 85.1 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family CO_deh_flav_C PF03450.12 EER27566.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase flavoprotein C-terminal domain HSF_DNA-bind PF00447.12 EER27567.1 - 3.9e-28 97.6 0.1 9.2e-28 96.4 0.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding TMF_DNA_bd PF12329.3 EER27567.1 - 0.021 14.6 2.7 0.027 14.2 0.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Orbi_VP1 PF05788.7 EER27567.1 - 0.036 11.2 0.0 0.05 10.8 0.0 1.1 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) Histone PF00125.19 EER27568.1 - 6.9e-22 77.3 0.0 9.1e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EER27568.1 - 5.2e-05 23.2 0.0 7.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pho88 PF10032.4 EER27569.1 - 5.6e-83 276.8 0.1 6.2e-83 276.7 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2576 PF10845.3 EER27569.1 - 0.0046 16.0 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2576) CitMHS PF03600.11 EER27569.1 - 0.037 12.6 0.1 0.046 12.3 0.1 1.0 1 0 0 1 1 1 0 Citrate transporter Gp_dh_C PF02800.15 EER27570.1 - 1.6e-73 245.3 0.1 2.4e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EER27570.1 - 1.3e-61 206.9 0.1 3e-61 205.8 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EER27570.1 - 0.0023 17.8 0.2 0.012 15.5 0.0 2.3 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EER27570.1 - 0.0089 15.5 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hist_deacetyl PF00850.14 EER27571.1 - 4.9e-96 321.6 0.1 1.1e-95 320.4 0.0 1.6 2 0 0 2 2 2 1 Histone deacetylase domain Arb2 PF09757.4 EER27571.1 - 1.1e-47 161.7 0.3 2e-47 160.9 0.2 1.4 1 0 0 1 1 1 1 Arb2 domain Sugar_tr PF00083.19 EER27572.1 - 4.3e-124 414.5 26.7 4.9e-124 414.3 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER27572.1 - 9.1e-26 90.3 34.6 1.4e-19 70.0 5.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EER27572.1 - 2.3e-05 23.0 29.2 0.00032 19.2 6.5 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein DUF3154 PF11351.3 EER27572.1 - 2.1 8.1 8.2 0.71 9.6 1.9 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3154) MFS_1 PF07690.11 EER27573.1 - 7.2e-33 113.7 36.4 7.2e-33 113.7 25.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M16 PF00675.15 EER27574.1 - 4.5e-30 104.3 9.9 5e-22 78.2 0.2 4.9 5 1 1 6 6 6 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EER27574.1 - 6.6e-30 104.1 0.0 5.6e-20 71.7 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain EF-hand_10 PF14788.1 EER27574.1 - 0.079 12.6 0.2 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 EF hand NUDIX_2 PF13869.1 EER27575.1 - 2.9e-82 274.5 0.0 3.4e-82 274.3 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF4316 PF14195.1 EER27575.1 - 0.096 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4316) CoaE PF01121.15 EER27576.1 - 3.6e-43 147.0 0.0 6.4e-43 146.2 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EER27576.1 - 0.00015 22.5 0.1 0.00028 21.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER27576.1 - 0.0059 16.4 0.0 0.038 13.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain ATP-synt_DE PF00401.15 EER27576.1 - 0.07 13.0 0.7 0.17 11.8 0.5 1.7 1 1 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain AAA_18 PF13238.1 EER27576.1 - 0.09 13.0 0.1 0.33 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain OAD_gamma PF04277.8 EER27577.1 - 0.003 17.8 3.2 2.1 8.8 0.0 2.7 2 1 0 2 2 2 2 Oxaloacetate decarboxylase, gamma chain YebO PF13974.1 EER27577.1 - 4.5 7.1 6.5 18 5.1 4.5 2.0 1 1 0 1 1 1 0 YebO-like protein zf-CHCC PF10276.4 EER27578.1 - 3.1e-17 62.1 0.5 5.1e-17 61.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger domain UPF0047 PF01894.12 EER27579.1 - 5.4e-41 139.1 0.0 6.1e-41 138.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 ECH PF00378.15 EER27580.1 - 4.9e-47 160.1 0.0 6.3e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EER27580.1 - 0.078 12.7 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S49 Pyr_redox_3 PF13738.1 EER27581.1 - 2.5e-18 66.8 0.0 4.8e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER27581.1 - 1.3e-14 53.2 0.1 1.4e-13 49.9 0.0 2.4 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EER27581.1 - 2.2e-05 23.5 0.0 8.2e-05 21.6 0.0 1.8 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EER27581.1 - 0.0001 22.2 0.4 0.00032 20.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EER27581.1 - 0.012 15.4 0.0 0.21 11.3 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EER27581.1 - 0.043 13.6 0.0 0.67 9.8 0.0 2.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2411 PF10304.4 EER27581.1 - 0.16 11.5 0.1 0.4 10.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Exo_endo_phos PF03372.18 EER27582.1 - 6.7e-25 88.4 0.0 1.2e-24 87.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CHY PF05495.7 EER27583.1 - 1.4e-12 47.5 17.4 1.9e-12 47.1 12.1 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 EER27583.1 - 0.019 14.9 1.3 0.019 14.9 0.9 2.5 1 1 1 2 2 2 0 zinc-finger Evr1_Alr PF04777.8 EER27583.1 - 0.09 12.6 11.9 0.5 10.2 8.2 2.1 1 1 0 1 1 1 0 Erv1 / Alr family Zn-ribbon_8 PF09723.5 EER27583.1 - 1.8 8.6 14.4 1.5 8.8 6.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Cytochrome_C7 PF14522.1 EER27583.1 - 1.8 8.2 14.0 2.9 7.5 9.7 1.3 1 0 0 1 1 1 0 Cytochrome c7 Proteasome PF00227.21 EER27584.1 - 1.2e-55 187.8 0.1 1.5e-55 187.4 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EER27584.1 - 2.6e-13 49.0 0.1 2.6e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 EER27584.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) AMP-binding PF00501.23 EER27585.1 - 2.1e-74 250.3 0.0 2.6e-74 250.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER27585.1 - 2.1e-16 60.6 0.2 6.5e-16 59.0 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF2464 PF10240.4 EER27585.1 - 0.051 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) DUF4048 PF13257.1 EER27586.1 - 1.5e-85 286.8 17.0 1.5e-85 286.8 11.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4048) Pkinase PF00069.20 EER27587.1 - 5.8e-71 238.6 0.0 9.1e-71 238.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27587.1 - 8.4e-48 162.6 0.0 1.3e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER27587.1 - 1.8e-06 27.1 0.0 1.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FAD-oxidase_C PF02913.14 EER27588.1 - 3.4e-57 193.6 0.0 4.7e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EER27588.1 - 8.8e-36 122.4 0.3 1.6e-35 121.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Tim17 PF02466.14 EER27589.1 - 2.3e-51 173.1 6.9 2.3e-51 173.1 4.8 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Oxidored_molyb PF00174.14 EER27590.1 - 2.2e-52 176.8 0.0 3.6e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EER27590.1 - 1.5e-26 92.5 1.4 3.1e-26 91.5 1.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Abhydrolase_6 PF12697.2 EER27591.1 - 1e-11 45.1 0.1 1.2e-11 44.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27591.1 - 1.4e-07 31.3 0.0 1.5e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EER27591.1 - 0.0014 18.8 0.0 0.0019 18.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain PALP PF00291.20 EER27593.1 - 7e-62 209.3 0.2 7e-62 209.3 0.1 1.3 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Cnd3 PF12719.2 EER27594.1 - 3.3e-101 338.2 0.1 3.7e-100 334.7 0.0 2.5 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EER27594.1 - 4e-11 43.0 3.5 4.1e-06 26.9 0.1 4.6 2 2 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 EER27594.1 - 8.2e-06 26.1 5.6 0.076 13.5 0.6 5.0 3 1 2 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EER27594.1 - 4.2e-05 23.2 5.1 0.17 12.0 0.0 6.2 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.15 EER27594.1 - 0.063 11.5 0.4 2.2 6.4 0.0 3.1 4 0 0 4 4 4 0 Adaptin N terminal region MMS19_N PF14500.1 EER27594.1 - 0.094 11.9 0.0 0.55 9.4 0.0 2.4 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II DUF1546 PF07571.8 EER27594.1 - 0.13 12.4 0.1 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Cnd1 PF12717.2 EER27594.1 - 0.2 11.4 1.3 67 3.2 0.0 4.1 5 2 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 zf-RanBP PF00641.13 EER27595.1 - 2e-19 68.3 8.1 5.7e-10 38.1 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EER27595.1 - 1.1e-08 34.5 0.0 2.6e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER27595.1 - 4e-07 29.9 0.0 3.5e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EER27595.1 - 3.5e-06 27.4 0.0 5.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 EER27595.1 - 0.79 9.5 8.0 0.51 10.1 0.6 2.4 2 0 0 2 2 2 0 Double zinc ribbon F-box-like PF12937.2 EER27596.1 - 1.4e-08 34.3 1.3 3.1e-08 33.2 0.9 1.7 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EER27597.1 - 0.0052 15.9 0.0 0.0056 15.8 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EER27597.1 - 0.0054 15.8 0.0 0.0081 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EER27597.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 EER27597.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family RmlD_sub_bind PF04321.12 EER27599.1 - 2.2e-46 158.0 0.0 3e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EER27599.1 - 1.9e-17 63.4 0.0 2.5e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EER27599.1 - 9.8e-10 37.7 0.0 3.3e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EER27599.1 - 6.5e-08 31.6 0.1 2.4e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EER27599.1 - 9.6e-05 22.4 0.1 0.00014 21.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EER27599.1 - 0.017 14.0 0.1 1.2 7.9 0.0 2.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EER27599.1 - 0.026 14.4 0.9 1.8 8.4 0.6 2.8 1 1 0 1 1 1 0 short chain dehydrogenase F-box-like PF12937.2 EER27600.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.1 2 0 0 2 2 2 0 F-box-like TrkH PF02386.11 EER27601.1 - 6.7e-113 376.8 13.1 1.3e-111 372.6 6.2 2.1 2 0 0 2 2 2 2 Cation transport protein DUF1938 PF09153.5 EER27601.1 - 0.058 13.2 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) Dynamin_M PF01031.15 EER27602.1 - 1.3e-105 352.3 0.5 2.3e-105 351.6 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EER27602.1 - 7.5e-57 191.7 0.2 1.7e-56 190.6 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EER27602.1 - 5.5e-29 99.9 5.0 1.4e-28 98.6 3.4 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EER27602.1 - 1.4e-05 25.0 0.7 0.00023 21.0 0.5 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER27602.1 - 0.00086 19.7 0.0 0.025 15.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein ATP-synt_ab PF00006.20 EER27603.1 - 1.1e-113 377.9 0.0 1.7e-113 377.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EER27603.1 - 3.4e-17 62.9 1.3 6e-17 62.1 0.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EER27603.1 - 6.4e-15 55.1 2.9 1.4e-14 54.0 2.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RVT_2 PF07727.9 EER27604.1 - 6.2e-69 231.6 0.0 1.9e-68 230.1 0.0 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EER27604.1 - 4.9e-19 68.6 0.0 2.6e-18 66.2 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EER27604.1 - 2.9e-06 26.8 0.1 7.2e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EER27604.1 - 1.2e-05 25.0 2.3 2.3e-05 24.0 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Phage_Gp23 PF10669.4 EER27604.1 - 0.77 9.8 9.8 0.062 13.4 1.8 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) WD40 PF00400.27 EER27605.1 - 3.9e-38 127.9 15.2 7e-07 28.8 0.5 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat CLTH PF10607.4 EER27605.1 - 1.3e-05 24.9 0.1 2e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain eIF2A PF08662.6 EER27605.1 - 3.2e-05 23.7 0.0 0.017 14.8 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EER27605.1 - 0.00018 19.9 0.0 0.025 12.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EER27605.1 - 0.0044 16.6 2.0 7.7 6.3 0.0 4.2 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EER27605.1 - 0.0088 14.3 0.0 0.94 7.6 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) Gmad1 PF10647.4 EER27605.1 - 0.052 12.9 0.0 2.3 7.5 0.1 3.1 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain DEAD PF00270.24 EER27606.1 - 9.4e-41 139.1 0.4 2.1e-40 138.0 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER27606.1 - 2.9e-29 100.7 0.2 5.6e-29 99.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EER27606.1 - 0.00022 20.8 0.2 0.00047 19.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EER27606.1 - 0.0007 19.4 0.0 0.0021 17.9 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EER27606.1 - 0.01 15.4 0.4 0.022 14.3 0.3 1.5 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EER27606.1 - 0.015 15.0 0.2 0.064 13.0 0.0 2.2 2 1 1 3 3 3 0 Flavivirus DEAD domain DsrH PF04077.7 EER27606.1 - 0.016 14.8 0.2 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 DsrH like protein Helicase_RecD PF05127.9 EER27606.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Helicase DUF1253 PF06862.7 EER27606.1 - 0.037 12.4 0.0 0.74 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_11 PF13086.1 EER27606.1 - 0.039 13.5 0.3 0.055 13.0 0.2 1.5 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EER27606.1 - 0.041 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain tRNA-synt_1b PF00579.20 EER27606.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) UvrD-helicase PF00580.16 EER27606.1 - 0.13 11.5 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EER27606.1 - 0.17 12.0 0.9 0.81 9.8 0.6 2.1 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 EER27607.1 - 4e-73 245.1 1.2 5e-72 241.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EER27607.1 - 2.1e-14 52.7 0.6 4.8e-14 51.5 0.4 1.7 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EER27607.1 - 8.3e-08 32.1 2.5 2.7e-06 27.3 1.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EER27607.1 - 4e-06 26.8 1.2 4e-06 26.8 0.8 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EER27607.1 - 0.00015 21.7 0.2 0.0036 17.3 0.1 2.7 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EER27607.1 - 0.071 12.6 0.0 0.24 10.9 0.0 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-LYAR PF08790.6 EER27607.1 - 0.13 11.9 0.1 0.35 10.6 0.1 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.21 EER27607.1 - 0.26 11.6 4.0 0.71 10.3 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER27607.1 - 0.82 10.1 2.9 8.9 6.9 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2570 PF10828.3 EER27607.1 - 2.7 7.6 5.3 0.92 9.1 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DNA_ligase_A_M PF01068.16 EER27608.1 - 1.3e-22 80.1 0.0 2.1e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EER27608.1 - 2e-11 44.0 0.0 4.1e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus APC8 PF04049.8 EER27609.1 - 2.8e-53 179.4 0.5 8.3e-53 177.9 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EER27609.1 - 2.2e-22 77.6 12.2 0.00015 21.1 0.0 8.4 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EER27609.1 - 2.4e-20 71.9 21.8 3.6e-07 29.7 0.1 6.8 6 1 1 7 7 7 5 TPR repeat TPR_2 PF07719.12 EER27609.1 - 7.1e-20 69.2 28.8 0.089 12.7 0.0 9.7 9 1 0 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EER27609.1 - 9.9e-19 67.5 28.8 5.3e-05 23.7 0.0 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EER27609.1 - 3.5e-17 60.8 12.6 0.00031 20.2 0.0 7.5 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EER27609.1 - 1.7e-15 56.1 23.0 0.0057 17.1 0.0 9.5 7 3 3 10 10 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EER27609.1 - 5.5e-11 42.6 14.3 0.073 13.4 0.2 7.8 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EER27609.1 - 4.2e-10 39.4 34.0 0.02 14.8 0.1 8.1 6 2 3 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EER27609.1 - 8.3e-09 35.4 14.9 0.28 11.3 0.1 5.9 6 0 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EER27609.1 - 2e-08 33.9 18.0 0.00053 19.7 0.3 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER27609.1 - 2.1e-08 33.7 8.3 0.69 10.2 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER27609.1 - 1.4e-07 30.7 10.4 0.95 9.4 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.1 EER27609.1 - 1.4e-06 28.3 29.7 0.87 10.1 0.2 10.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_15 PF13429.1 EER27609.1 - 0.00093 18.3 13.5 0.0023 17.0 5.6 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat SGT1 PF07093.6 EER27609.1 - 0.048 12.0 2.7 0.075 11.4 1.9 1.2 1 0 0 1 1 1 0 SGT1 protein TPR_10 PF13374.1 EER27609.1 - 0.18 11.7 24.2 17 5.5 0.0 8.6 10 0 0 10 10 9 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 EER27610.1 - 6.2e-66 221.9 0.0 7.4e-66 221.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Glycogen_syn PF05693.8 EER27611.1 - 0 1110.5 0.0 0 1110.3 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EER27611.1 - 1.6e-06 27.6 0.0 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EER27611.1 - 8.2e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EER27611.1 - 0.00011 22.3 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Vps54 PF07928.7 EER27613.1 - 2.6e-47 160.3 1.2 6.7e-47 159.0 0.2 2.2 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EER27613.1 - 4e-07 29.2 1.7 2.7e-06 26.4 1.0 2.5 3 1 0 3 3 3 1 Protein of unknown function N-terminal domain (DUF2450) LUC7 PF03194.10 EER27613.1 - 0.0023 17.4 1.6 0.0044 16.5 1.1 1.3 1 0 0 1 1 1 1 LUC7 N_terminus Cytochrom_B562 PF07361.6 EER27613.1 - 0.036 14.4 0.1 4.9 7.6 0.1 3.3 2 1 0 2 2 2 0 Cytochrome b562 MCM PF00493.18 EER27614.1 - 1.4e-141 471.1 0.2 1.9e-141 470.6 0.2 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EER27614.1 - 9.2e-19 68.1 0.3 2.3e-18 66.8 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EER27614.1 - 7e-07 28.6 0.0 0.00016 20.8 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EER27614.1 - 2.1e-05 24.2 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EER27614.1 - 0.00091 18.8 0.1 0.0039 16.8 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EER27614.1 - 0.03 13.7 0.1 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_2 PF13335.1 EER27614.1 - 0.064 13.6 1.5 0.11 12.8 0.4 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ECH PF00378.15 EER27615.1 - 1.6e-36 125.6 0.0 1.2e-24 86.8 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family PfkB PF00294.19 EER27616.1 - 1.2e-39 136.3 0.0 1.7e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase NYAP_N PF15439.1 EER27616.1 - 0.021 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter DUF3080 PF11279.3 EER27616.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3080) Tau95 PF09734.4 EER27618.1 - 1.5e-73 247.8 0.0 1.9e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Nop14 PF04147.7 EER27618.1 - 3.3 5.4 13.1 4.6 5.0 9.1 1.1 1 0 0 1 1 1 0 Nop14-like family B56 PF01603.15 EER27619.1 - 1.3e-174 580.5 4.2 1.7e-174 580.2 2.9 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FAT PF02259.18 EER27620.1 - 3.4e-74 249.9 6.9 8.1e-74 248.6 4.8 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EER27620.1 - 4.4e-29 101.6 0.4 2.4e-28 99.2 0.3 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EER27620.1 - 2.4e-06 26.8 0.3 5.9e-06 25.6 0.2 1.7 1 0 0 1 1 1 1 FATC domain DUF572 PF04502.8 EER27621.1 - 6.8e-74 249.0 10.3 7.9e-74 248.7 7.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 EER27621.1 - 0.011 15.2 0.3 0.021 14.3 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Benyvirus_14KDa PF07255.6 EER27621.1 - 0.027 14.3 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Benyvirus 14KDa protein zinc_ribbon_5 PF13719.1 EER27621.1 - 0.034 13.7 0.1 9.8 5.8 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-FCS PF06467.9 EER27621.1 - 0.041 13.5 2.9 0.22 11.2 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zinc_ribbon_4 PF13717.1 EER27621.1 - 0.051 13.2 0.2 9.5 6.0 0.0 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EER27621.1 - 0.11 11.7 0.3 0.52 9.5 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 EER27621.1 - 0.18 11.2 2.0 12 5.4 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit SprT-like PF10263.4 EER27621.1 - 1 9.0 3.1 1.4 8.5 1.5 1.7 1 1 1 2 2 2 0 SprT-like family TF_Zn_Ribbon PF08271.7 EER27621.1 - 1.1 8.5 6.2 2.7 7.3 1.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding TPR_11 PF13414.1 EER27622.1 - 8.9e-28 95.7 20.2 5.5e-08 32.3 0.0 8.8 7 2 0 8 8 8 5 TPR repeat TPR_1 PF00515.23 EER27622.1 - 1.5e-27 94.0 5.9 0.00029 20.3 0.6 10.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_2 PF07719.12 EER27622.1 - 6e-27 91.3 12.8 0.00027 20.6 0.3 10.6 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 EER27622.1 - 1.3e-25 89.3 14.2 1.9e-20 72.7 1.2 6.0 6 0 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EER27622.1 - 1e-16 60.6 26.7 2e-07 30.8 0.0 9.3 6 3 4 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EER27622.1 - 1.6e-14 54.0 11.7 0.018 15.3 0.0 7.6 8 1 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EER27622.1 - 2.8e-14 53.3 22.2 6.5e-05 23.4 0.2 9.1 7 4 1 9 9 9 4 Tetratricopeptide repeat TPR_8 PF13181.1 EER27622.1 - 5.9e-14 50.7 1.8 0.063 13.0 0.0 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EER27622.1 - 6.8e-13 48.0 21.4 0.44 11.3 0.2 10.4 8 3 3 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EER27622.1 - 1.1e-08 34.1 18.2 1.3 8.9 0.1 9.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EER27622.1 - 4.4e-07 29.9 12.9 0.46 11.0 0.2 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER27622.1 - 5.8e-07 29.2 8.9 0.3 11.3 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 EER27622.1 - 8.6e-06 25.5 15.2 0.032 14.1 0.0 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_21 PF09976.4 EER27622.1 - 0.0074 16.2 6.5 4.1 7.3 0.0 5.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EER27622.1 - 0.46 10.3 22.7 5.5 6.9 0.4 7.1 7 3 2 9 9 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 EER27622.1 - 1.1 9.9 27.1 0.61 10.6 0.1 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat Fungal_trans PF04082.13 EER27623.1 - 3.4e-16 58.9 0.2 1.1e-15 57.1 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER27623.1 - 1.6e-06 27.8 12.2 3.3e-06 26.8 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DinB_2 PF12867.2 EER27623.1 - 0.082 13.2 0.3 0.69 10.2 0.2 2.3 1 1 0 1 1 1 0 DinB superfamily Peptidase_C16 PF01831.12 EER27623.1 - 0.18 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase C16 family MFS_1 PF07690.11 EER27624.1 - 9.4e-42 142.9 31.4 9.4e-42 142.9 21.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER27624.1 - 3.2e-11 42.5 31.7 8.2e-11 41.1 21.9 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EER27624.1 - 4.3e-11 41.7 4.1 7.4e-11 40.9 2.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase_5 PF13507.1 EER27625.1 - 1.5e-96 322.2 0.0 2.7e-96 321.4 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EER27625.1 - 2.8e-44 150.8 0.2 5.6e-21 75.1 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EER27625.1 - 4e-26 91.1 0.3 2.7e-25 88.4 0.0 2.5 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Pox_P4B PF03292.9 EER27625.1 - 0.57 8.0 0.0 0.85 7.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus P4B major core protein Spc97_Spc98 PF04130.8 EER27626.1 - 4.2e-70 236.5 3.9 5.4e-70 236.2 2.7 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family MutS_III PF05192.13 EER27626.1 - 4.9e-05 23.2 0.5 0.015 15.0 0.0 2.3 2 0 0 2 2 2 2 MutS domain III Glyco_transf_15 PF01793.11 EER27627.1 - 2.5e-135 450.7 10.0 2.9e-135 450.4 7.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase COX5A PF02284.11 EER27628.1 - 4.1e-39 132.8 0.7 5.5e-39 132.4 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DUF488 PF04343.8 EER27628.1 - 0.079 13.3 1.3 1.5 9.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function, DUF488 DHC_N1 PF08385.7 EER27628.1 - 0.12 10.7 0.2 0.94 7.7 0.0 1.9 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 ELO PF01151.13 EER27629.1 - 8.5e-64 215.2 19.9 1e-63 215.0 13.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family AA_permease_2 PF13520.1 EER27631.1 - 1.1e-42 146.0 37.1 1.6e-42 145.5 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER27631.1 - 2.6e-20 72.2 33.5 3.4e-20 71.8 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease adh_short_C2 PF13561.1 EER27632.1 - 6.3e-34 117.8 0.0 8.4e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER27632.1 - 9.8e-30 103.6 0.1 1.2e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER27632.1 - 3.4e-06 26.8 0.5 1e-05 25.2 0.3 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EER27632.1 - 0.0087 15.5 0.1 0.016 14.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EER27632.1 - 0.066 13.2 0.2 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding AdoHcyase_NAD PF00670.16 EER27632.1 - 0.25 11.1 2.5 0.41 10.4 1.7 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EER27632.1 - 0.37 10.6 3.0 0.83 9.4 2.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1996 PF09362.5 EER27633.1 - 7.2e-82 274.5 0.0 9.5e-82 274.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) ActA PF05058.7 EER27633.1 - 0.1 10.5 1.8 0.13 10.2 1.2 1.2 1 0 0 1 1 1 0 ActA Protein 2-Hacid_dh_C PF02826.14 EER27635.1 - 1.9e-45 154.2 0.0 2.7e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER27635.1 - 5.4e-09 35.6 0.0 2.6e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EER27635.1 - 8.4e-06 25.7 0.1 1.8e-05 24.6 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EER27635.1 - 0.0058 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EER27635.1 - 0.024 14.0 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 EER27635.1 - 0.08 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_10 PF13460.1 EER27635.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Asparaginase PF00710.15 EER27636.1 - 4.8e-103 344.3 0.0 5.9e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EER27636.1 - 5.1e-14 52.3 0.1 8.9e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EER27636.1 - 9.4e-10 38.4 0.3 2.4e-08 33.9 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EER27636.1 - 1.1e-09 37.6 3.7 1.1e-05 25.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EER27636.1 - 1.7e-08 34.7 0.4 7e-06 26.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER27636.1 - 1.5e-06 27.8 1.0 0.21 11.9 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat MTTB PF06253.6 EER27636.1 - 0.023 12.4 0.2 0.032 11.9 0.1 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Viral_protease PF08715.5 EER27636.1 - 0.11 11.5 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 Papain like viral protease NmrA PF05368.8 EER27637.1 - 1.6e-69 233.7 0.0 2e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EER27637.1 - 3.4e-05 23.9 0.0 5.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1876 PF08962.6 EER27637.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) NAP PF00956.13 EER27638.1 - 1.6e-38 132.2 6.5 3.4e-38 131.1 4.5 1.5 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Syntaxin-6_N PF09177.6 EER27639.1 - 1.1e-24 86.6 1.1 1.7e-23 82.8 0.0 2.3 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EER27639.1 - 8.9e-13 47.7 2.7 8.9e-13 47.7 1.9 3.0 3 0 0 3 3 3 1 SNARE domain Snapin_Pallidin PF14712.1 EER27639.1 - 0.12 12.6 2.9 4.4 7.6 0.1 2.5 2 1 0 2 2 2 0 Snapin/Pallidin DUF2650 PF10853.3 EER27639.1 - 0.17 11.3 1.7 0.27 10.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) DUF3355 PF11835.3 EER27639.1 - 0.18 11.5 0.1 0.51 10.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3355) DUF1664 PF07889.7 EER27639.1 - 0.34 10.7 2.2 4.8 6.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EER27639.1 - 0.36 11.0 5.2 1.5 9.1 0.1 3.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF883 PF05957.8 EER27639.1 - 0.42 11.0 3.7 10 6.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TBPIP PF07106.8 EER27639.1 - 0.5 9.9 3.2 1.9 7.9 0.1 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EER27639.1 - 0.5 10.7 3.7 2.8 8.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Rifin_STEVOR PF02009.11 EER27639.1 - 0.65 9.5 2.3 1.1 8.7 1.6 1.4 1 1 0 1 1 1 0 Rifin/stevor family Tropomyosin_1 PF12718.2 EER27639.1 - 1.2 8.9 9.2 4.5 7.1 0.6 2.1 2 0 0 2 2 2 0 Tropomyosin like Methyltransf_32 PF13679.1 EER27640.1 - 7.7e-21 74.2 0.2 1.5e-20 73.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain DUF2624 PF11116.3 EER27640.1 - 0.76 10.3 2.4 0.99 9.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) PTR2 PF00854.16 EER27641.1 - 3.8e-44 151.0 11.1 1.3e-43 149.2 7.7 1.8 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EER27641.1 - 1.3e-09 37.3 19.5 3.8e-09 35.7 13.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER27641.1 - 0.76 8.2 24.7 0.037 12.6 9.0 3.4 3 1 0 3 3 3 0 Sugar (and other) transporter Ank_2 PF12796.2 EER27642.1 - 8.4e-36 122.1 0.8 4.1e-10 39.8 0.0 6.7 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EER27642.1 - 2.3e-28 96.5 10.6 2.4e-06 27.0 0.0 10.1 10 0 0 10 10 10 6 Ankyrin repeat Pkinase PF00069.20 EER27642.1 - 5.3e-28 97.8 0.0 8.9e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_4 PF13637.1 EER27642.1 - 5.7e-25 87.2 7.1 2.4e-05 24.6 0.0 8.8 6 3 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER27642.1 - 1.2e-24 85.7 12.6 2.7e-06 27.4 0.0 9.6 7 3 3 10 10 10 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 EER27642.1 - 2.3e-24 85.8 0.0 5.4e-24 84.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_3 PF13606.1 EER27642.1 - 3.6e-24 82.4 6.1 0.0001 22.1 0.0 10.6 11 0 0 11 11 11 5 Ankyrin repeat Pkinase_Tyr PF07714.12 EER27643.1 - 6.1e-08 32.0 0.0 9.3e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EER27643.1 - 1e-05 24.8 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LCCL PF03815.14 EER27644.1 - 3.3e-21 75.0 0.3 5e-21 74.4 0.2 1.2 1 0 0 1 1 1 1 LCCL domain OppC_N PF12911.2 EER27644.1 - 0.06 12.7 0.2 0.06 12.7 0.2 2.8 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C Aminotran_1_2 PF00155.16 EER27645.1 - 2.7e-12 46.3 0.0 4.3e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II UPF0029 PF01205.14 EER27646.1 - 1.4e-33 114.8 0.1 2.8e-33 113.9 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EER27646.1 - 3.4e-09 36.5 0.0 6.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 RWD domain DUF4113 PF13438.1 EER27646.1 - 0.038 13.5 0.3 0.4 10.3 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4113) Chitin_bind_3 PF03067.10 EER27647.1 - 0.0015 18.8 0.0 0.0025 18.1 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 EER27647.1 - 0.004 16.9 0.0 0.0074 16.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF605 PF04652.11 EER27647.1 - 5 6.4 18.2 7.3 5.8 12.6 1.1 1 0 0 1 1 1 0 Vta1 like Ribosomal_L4 PF00573.17 EER27648.1 - 4.4e-41 140.3 0.2 6.1e-41 139.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EER27648.1 - 6.3e-31 106.0 0.9 1.4e-30 104.9 0.7 1.6 1 0 0 1 1 1 1 60S ribosomal protein L4 C-terminal domain NAAA-beta PF15508.1 EER27649.1 - 2.8e-23 82.0 0.0 5.6e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF3395 PF11875.3 EER27650.1 - 4.3e-42 143.3 0.1 6.7e-42 142.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EER27650.1 - 2.2e-14 52.8 0.4 4.5e-14 51.9 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain SKIP_SNW PF02731.10 EER27653.1 - 4.3e-68 227.7 6.3 4.3e-68 227.7 4.4 2.4 2 0 0 2 2 2 1 SKIP/SNW domain WD40 PF00400.27 EER27654.1 - 1.2e-51 170.8 23.9 9.1e-12 44.3 0.1 12.4 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 EER27654.1 - 1.4e-31 108.6 0.0 2.1e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EER27654.1 - 8.6e-07 28.8 1.0 0.017 14.8 0.1 5.8 4 1 3 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EER27654.1 - 5.5e-05 21.4 3.3 0.11 10.5 1.0 4.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EER27654.1 - 0.22 10.2 0.0 1.8 7.2 0.0 2.5 3 0 0 3 3 3 0 Coatomer WD associated region Septin PF00735.13 EER27655.1 - 2e-117 391.2 0.4 2e-117 391.2 0.3 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EER27655.1 - 3.4e-07 30.2 0.0 7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER27655.1 - 1.3e-06 27.9 0.1 4.9e-05 22.8 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EER27655.1 - 1.4e-05 24.3 0.0 4e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EER27655.1 - 0.0024 18.3 0.1 0.0089 16.5 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EER27655.1 - 0.0032 17.0 0.1 0.0068 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EER27655.1 - 0.0058 16.7 0.6 0.024 14.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain IIGP PF05049.8 EER27655.1 - 0.0064 15.3 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EER27655.1 - 0.0095 15.4 0.8 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family AIG1 PF04548.11 EER27655.1 - 0.0098 15.0 0.0 0.022 13.8 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Pox_A32 PF04665.7 EER27655.1 - 0.013 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EER27655.1 - 0.02 14.2 0.9 0.058 12.7 0.3 2.0 2 1 0 2 2 2 0 Ras family T2SE PF00437.15 EER27655.1 - 0.021 13.7 0.4 0.095 11.5 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 EER27655.1 - 0.021 15.1 0.2 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 EER27655.1 - 0.04 13.5 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EER27655.1 - 0.07 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.18 EER27655.1 - 0.074 12.8 7.4 0.62 9.8 0.0 3.2 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.1 EER27655.1 - 0.079 12.9 1.1 0.62 10.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain PduV-EutP PF10662.4 EER27655.1 - 0.097 12.1 1.0 2.7 7.4 0.3 2.7 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EER27655.1 - 0.11 12.1 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EER27655.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.12 EER27655.1 - 0.18 11.3 0.7 9.3 5.7 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EER27655.1 - 0.2 10.4 3.0 1 8.1 0.0 2.7 3 0 0 3 3 3 0 ArgK protein KAP_NTPase PF07693.9 EER27655.1 - 0.29 10.0 3.4 0.53 9.2 2.4 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Atg14 PF10186.4 EER27655.1 - 0.66 8.8 6.0 1.6 7.6 4.1 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 EER27656.1 - 1.6e-34 116.5 17.6 1.4e-06 27.9 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ PF01011.16 EER27656.1 - 0.002 17.5 0.1 0.2 11.2 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat VID27 PF08553.5 EER27656.1 - 0.031 12.5 1.2 0.049 11.8 0.2 1.7 2 1 0 2 2 2 0 VID27 cytoplasmic protein DUF1513 PF07433.6 EER27656.1 - 0.086 11.7 0.8 9.4 5.0 0.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1513) DUF3312 PF11768.3 EER27656.1 - 0.14 10.3 0.0 0.23 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) XRN_N PF03159.13 EER27657.1 - 1.4e-104 348.6 0.0 2.7e-104 347.7 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus WD40 PF00400.27 EER27658.1 - 8.1e-44 145.9 5.7 1.5e-08 34.1 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EER27658.1 - 6.7e-30 102.8 0.8 1.5e-29 101.6 0.6 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex GTP_cyclohydroI PF01227.17 EER27659.1 - 6.3e-73 243.8 0.2 8.6e-73 243.4 0.1 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EER27659.1 - 0.0014 18.4 0.0 0.004 17.0 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein DUF4243 PF14027.1 EER27661.1 - 1.6e-105 353.1 0.2 2e-105 352.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pkinase PF00069.20 EER27662.1 - 6.5e-14 51.7 0.0 2.5e-13 49.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27662.1 - 0.0023 17.0 0.0 0.38 9.7 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EER27662.1 - 0.087 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER27662.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EER27663.1 - 2.2e-70 236.8 0.0 3.8e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27663.1 - 2.5e-33 115.2 0.0 4.7e-33 114.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER27663.1 - 0.00031 19.8 0.1 0.0011 17.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EER27663.1 - 0.001 18.1 0.1 0.0024 16.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family NUDIX PF00293.23 EER27664.1 - 8.8e-17 61.0 0.1 1.5e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EER27664.1 - 8.8e-17 61.2 0.0 1.9e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EER27664.1 - 3.9e-07 29.4 1.4 7.2e-07 28.6 1.0 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF1675 PF07897.6 EER27665.1 - 0.15 11.8 7.2 0.26 11.1 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Dynamin_N PF00350.18 EER27666.1 - 5.6e-14 52.3 0.0 1.1e-13 51.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EER27666.1 - 1.6e-08 33.7 0.2 1.7e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin central region AAA_23 PF13476.1 EER27666.1 - 0.0021 18.4 0.7 0.017 15.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EER27666.1 - 0.0051 17.1 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 EER27666.1 - 0.0092 15.9 0.0 0.031 14.2 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF3340 PF11818.3 EER27666.1 - 0.024 14.6 0.0 0.068 13.1 0.0 1.8 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Miro PF08477.8 EER27666.1 - 0.024 15.1 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein PduV-EutP PF10662.4 EER27666.1 - 0.03 13.8 0.0 0.97 8.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Prp18 PF02840.10 EER27667.1 - 2.6e-53 179.7 1.5 2.7e-53 179.7 0.0 1.8 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EER27667.1 - 2.5e-13 49.0 1.6 2.5e-13 49.0 1.1 3.4 3 1 1 4 4 4 1 pre-mRNA processing factor 4 (PRP4) like Ycf1 PF05758.7 EER27667.1 - 6.2 4.3 8.6 6.1 4.4 6.0 1.1 1 0 0 1 1 1 0 Ycf1 Helicase_C_3 PF13625.1 EER27668.1 - 8.3e-27 93.4 0.0 4.1e-26 91.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER27668.1 - 8.6e-15 55.0 0.0 1.6e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EER27668.1 - 1.3e-12 47.4 0.0 2.9e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EER27668.1 - 2.7e-11 42.8 0.2 4.6e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EER27668.1 - 1.2e-06 28.1 0.0 3.1e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EER27668.1 - 0.0026 16.5 0.1 0.0044 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF676 PF05057.9 EER27671.1 - 1.1e-06 28.1 0.0 2.2e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EER27671.1 - 0.0005 19.7 0.0 0.005 16.4 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EER27671.1 - 0.00088 19.2 0.1 0.0023 17.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27671.1 - 0.019 14.7 0.0 0.071 12.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EER27671.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF829 PF05705.9 EER27671.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) CTD_bind PF04818.8 EER27672.1 - 0.0015 18.7 0.0 0.0035 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. EMP24_GP25L PF01105.19 EER27673.1 - 2.3e-44 151.3 0.2 2.6e-44 151.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD USP7_ICP0_bdg PF12436.3 EER27674.1 - 1.3e-84 283.3 0.1 4.2e-83 278.4 0.0 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EER27674.1 - 2.5e-70 236.2 5.3 4.9e-70 235.2 2.3 2.5 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EER27674.1 - 2.1e-55 187.7 0.5 3.2e-55 187.1 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER27674.1 - 4.7e-30 105.0 0.0 7.6e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EER27674.1 - 1.8e-09 37.8 0.0 8.4e-09 35.7 0.0 2.3 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.3 EER27674.1 - 0.07 12.8 2.2 28 4.4 0.0 4.2 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like BCDHK_Adom3 PF10436.4 EER27675.1 - 3.2e-47 160.1 0.5 8.7e-47 158.6 0.2 1.7 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EER27675.1 - 2e-10 40.3 0.0 1.2e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EER27675.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EER27675.1 - 0.037 13.8 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain SPC22 PF04573.7 EER27677.1 - 3.2e-32 111.1 0.0 1.2e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 Signal peptidase subunit Peptidase_C48 PF02902.14 EER27678.1 - 6.3e-33 114.2 0.5 7.4e-32 110.7 0.3 2.3 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain IF4E PF01652.13 EER27679.1 - 7.8e-53 178.3 0.1 1.1e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Aminotran_1_2 PF00155.16 EER27680.1 - 1.2e-22 80.4 0.0 1.4e-22 80.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EER27680.1 - 0.097 11.7 0.0 0.17 11.0 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase POT1 PF02765.12 EER27681.1 - 8.8e-19 67.8 0.0 1.4e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.14 EER27682.1 - 6e-44 150.1 0.0 3.1e-24 85.0 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EER27682.1 - 2.8e-15 56.9 0.0 2.3e-14 53.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER27682.1 - 3.3e-08 33.6 0.0 0.0024 17.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER27682.1 - 5.6e-08 32.6 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EER27682.1 - 1.3e-07 31.5 0.6 1.8e-06 27.8 0.1 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EER27682.1 - 2.6e-07 29.8 0.1 6.1e-06 25.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EER27682.1 - 8.9e-05 21.6 0.1 0.00062 18.9 0.0 2.2 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EER27682.1 - 0.012 14.5 0.2 0.83 8.4 0.1 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EER27682.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Strep_67kDa_ant PF06100.6 EER27682.1 - 0.11 10.8 0.1 1.5 7.0 0.0 2.0 2 0 0 2 2 2 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family FAD_binding_2 PF00890.19 EER27682.1 - 0.22 10.3 3.6 5.6 5.7 2.0 2.2 1 1 1 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EER27682.1 - 0.23 9.8 0.1 0.5 8.7 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein HDA2-3 PF11496.3 EER27683.1 - 2.6e-33 115.0 0.0 9.5e-32 109.9 0.0 2.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CP12 PF02672.10 EER27683.1 - 1.4 9.4 8.2 1.6 9.2 0.4 3.2 1 1 1 2 2 2 0 CP12 domain GAS PF13851.1 EER27683.1 - 4.2 6.5 36.0 4.4 6.4 4.1 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 EER27683.1 - 6 6.2 41.5 54 3.1 28.9 2.2 1 1 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 EER27683.1 - 6.7 5.7 6.2 7.8 5.5 0.5 2.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 EER27683.1 - 7.7 6.2 23.6 5.8 6.6 6.2 3.4 2 1 1 3 3 3 0 Laminin Domain II MIP PF00230.15 EER27684.1 - 2.5e-35 121.9 18.3 3.1e-35 121.7 12.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein IF-2B PF01008.12 EER27685.1 - 3.3e-21 75.5 0.0 6e-21 74.6 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Transglut_core PF01841.14 EER27686.1 - 2e-09 37.6 0.2 5.3e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EER27686.1 - 2.2e-08 33.4 0.2 6.6e-08 31.9 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EER27686.1 - 6e-08 31.9 1.6 8.7e-07 28.2 0.0 2.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EER27686.1 - 4e-05 23.0 3.6 6.8e-05 22.3 0.1 3.1 4 0 0 4 4 4 1 Variant SH3 domain Transglut_core2 PF13369.1 EER27686.1 - 0.075 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily DHHA2 PF02833.9 EER27687.1 - 1.9e-17 63.6 0.0 3.2e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EER27687.1 - 0.00033 20.3 0.0 0.0062 16.1 0.0 2.3 1 1 0 1 1 1 1 DHH family PLU-1 PF08429.6 EER27688.1 - 4.3e-106 354.5 14.4 8.1e-104 347.1 10.0 2.3 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EER27688.1 - 6.4e-44 148.8 0.3 1.7e-43 147.4 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EER27688.1 - 6e-27 93.3 0.0 1.8e-26 91.7 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EER27688.1 - 9.5e-19 66.6 3.1 2.3e-18 65.3 2.2 1.7 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 EER27688.1 - 1.5e-18 66.1 28.0 5.6e-10 38.7 4.6 3.5 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.11 EER27688.1 - 3.2e-14 52.7 9.5 9e-14 51.2 6.6 1.9 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.1 EER27688.1 - 0.002 17.4 8.9 0.016 14.5 0.6 2.8 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain GIY-YIG PF01541.19 EER27689.1 - 2e-07 31.2 0.0 4.4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EER27689.1 - 9.2e-05 22.3 5.8 0.00018 21.3 4.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-4CXXC_R1 PF10497.4 EER27689.1 - 0.048 13.8 3.0 0.083 13.0 2.1 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Thymidylate_kin PF02223.12 EER27690.1 - 3.8e-44 150.2 0.0 4.4e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EER27690.1 - 0.012 14.8 0.4 0.025 13.7 0.0 1.7 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 EER27690.1 - 0.084 12.7 0.1 0.15 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain TGT PF01702.13 EER27691.1 - 2.2e-41 141.7 0.0 3.1e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.11 EER27692.1 - 3.6e-32 111.4 23.7 3.6e-32 111.4 16.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Ilm1 PF10311.4 EER27692.1 - 0.064 12.7 0.1 0.19 11.2 0.0 1.8 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 DUF1049 PF06305.6 EER27692.1 - 0.17 11.3 1.3 12 5.4 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Wzy_C PF04932.10 EER27692.1 - 3.3 7.4 8.4 1.4 8.6 0.1 2.7 1 1 0 2 2 2 0 O-Antigen ligase PEP_mutase PF13714.1 EER27693.1 - 9.6e-56 188.6 0.0 1.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EER27693.1 - 2.2e-12 46.0 0.1 3.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EER27693.1 - 0.0013 17.9 0.0 0.0099 15.0 0.0 2.0 1 1 0 2 2 2 1 Ketopantoate hydroxymethyltransferase MTHFR PF02219.12 EER27694.1 - 1.3e-99 332.9 0.0 2e-99 332.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase NDK PF00334.14 EER27695.1 - 2.2e-55 186.1 0.0 2.5e-55 185.9 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 EER27696.1 - 2.9e-149 497.6 6.6 3.6e-149 497.3 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EER27696.1 - 1.8e-23 82.1 0.1 4.8e-23 80.7 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like PQ-loop PF04193.9 EER27697.1 - 1.3e-13 50.2 0.4 1.3e-13 50.2 0.3 2.7 3 0 0 3 3 3 2 PQ loop repeat NMT1 PF09084.6 EER27698.1 - 0.0099 15.4 0.0 0.12 11.9 0.0 2.2 1 1 1 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.1 EER27698.1 - 0.045 13.1 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family Glyco_hydro_16 PF00722.16 EER27699.1 - 2.8e-09 36.5 0.0 2.8e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Pkinase PF00069.20 EER27700.1 - 0.039 13.0 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Ribosomal_L1 PF00687.16 EER27701.1 - 1.7e-33 115.8 0.0 2.7e-33 115.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 EER27702.1 - 3.8e-31 107.7 0.9 3.8e-31 107.7 0.6 1.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EER27702.1 - 7.2e-07 28.9 1.9 2.6e-06 27.1 0.2 2.7 2 1 1 3 3 3 1 Vps51/Vps67 Sigma70_ner PF04546.8 EER27702.1 - 0.00047 19.8 1.0 0.00083 19.0 0.7 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region Sec8_exocyst PF04048.9 EER27702.1 - 0.022 14.4 0.6 0.13 11.8 0.2 2.2 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Bul1_C PF04426.7 EER27702.1 - 0.056 12.6 0.4 0.56 9.3 0.0 2.1 1 1 1 2 2 2 0 Bul1 C terminus Baculo_PEP_C PF04513.7 EER27702.1 - 0.058 13.2 0.5 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EER27702.1 - 0.19 11.6 1.3 19 5.2 0.0 3.2 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) RNA_pol_3_Rpc31 PF11705.3 EER27702.1 - 0.21 11.5 8.2 0.42 10.4 5.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Atg14 PF10186.4 EER27702.1 - 0.55 9.1 3.9 0.76 8.6 2.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ParA PF10609.4 EER27704.1 - 2.9e-34 116.8 0.0 6.1e-34 115.7 0.0 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EER27704.1 - 4.1e-12 45.9 0.0 6.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EER27704.1 - 7.7e-06 25.1 0.0 0.00015 20.9 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EER27704.1 - 0.0001 22.2 0.0 0.0005 20.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EER27704.1 - 0.0011 18.0 1.4 0.0027 16.7 0.7 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EER27704.1 - 0.0024 17.3 0.1 0.0042 16.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EER27704.1 - 0.012 14.4 0.2 0.018 13.8 0.2 1.2 1 0 0 1 1 1 0 ArgK protein AAA_26 PF13500.1 EER27704.1 - 0.039 13.5 0.4 10 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 EER27704.1 - 0.053 13.1 0.1 0.082 12.5 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase IstB_IS21 PF01695.12 EER27704.1 - 0.086 12.2 0.0 0.5 9.7 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein OrfB_Zn_ribbon PF07282.6 EER27704.1 - 0.12 12.0 0.2 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain YhjQ PF06564.7 EER27704.1 - 0.13 11.6 0.6 0.41 9.9 0.2 1.8 2 0 0 2 2 2 0 YhjQ protein Desulfoferrod_N PF06397.7 EER27704.1 - 0.71 9.3 5.4 0.11 11.9 0.6 1.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain SEP PF08059.8 EER27705.1 - 3.3e-27 94.5 0.1 6.2e-27 93.7 0.1 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EER27705.1 - 9.3e-16 57.6 0.0 1.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EER27705.1 - 5e-13 48.3 0.0 8.3e-13 47.6 0.0 1.3 1 0 0 1 1 1 1 UBA-like domain Dehydrin PF00257.14 EER27705.1 - 0.021 15.1 1.3 0.034 14.4 0.2 1.8 2 0 0 2 2 2 0 Dehydrin TOM13 PF08219.6 EER27706.1 - 2.3e-31 107.4 0.0 3.5e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Outer membrane protein TOM13 Secretin_N PF03958.12 EER27706.1 - 0.024 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain 60KD_IMP PF02096.15 EER27707.1 - 1.2e-36 126.2 0.6 1.2e-36 126.2 0.4 1.9 2 0 0 2 2 2 1 60Kd inner membrane protein Cytochrom_C PF00034.16 EER27707.1 - 0.16 12.8 0.1 0.35 11.7 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c TAFII28 PF04719.9 EER27708.1 - 5.1e-22 77.4 0.1 1.9e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 hTAFII28-like protein conserved region SAM_decarbox PF01536.11 EER27709.1 - 1.6e-87 293.2 0.0 2.9e-86 289.1 0.0 2.4 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1546 PF07571.8 EER27710.1 - 1.3e-31 108.5 0.0 4.3e-31 106.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 EER27710.1 - 8.6e-24 83.2 0.0 1.7e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EER27710.1 - 0.00027 20.9 0.1 0.0037 17.3 0.0 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 EER27710.1 - 0.15 11.8 0.1 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CRAL_TRIO PF00650.15 EER27711.1 - 5.6e-16 58.4 0.1 1.2e-15 57.3 0.1 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EER27711.1 - 1.8e-05 24.7 0.0 4.8e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain P35 PF02331.10 EER27711.1 - 0.061 12.4 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Apoptosis preventing protein IPP-2 PF04979.9 EER27712.1 - 5.7e-11 42.7 13.8 2.7e-06 27.6 0.8 2.7 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) CAF1A PF12253.3 EER27714.1 - 1e-27 96.0 8.0 1e-27 96.0 5.6 3.7 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EER27714.1 - 2.5e-10 40.1 76.5 7.3e-10 38.5 52.9 1.8 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mem_trans PF03547.13 EER27714.1 - 4.2 5.5 4.8 6.3 4.9 3.3 1.3 1 0 0 1 1 1 0 Membrane transport protein IncA PF04156.9 EER27714.1 - 8 6.0 18.8 18 4.8 13.0 1.6 1 0 0 1 1 1 0 IncA protein GSDH PF07995.6 EER27716.1 - 1.1e-07 31.3 0.0 6.7e-06 25.4 0.0 2.8 1 1 2 3 3 3 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EER27716.1 - 0.00025 20.5 0.0 0.006 15.9 0.0 2.2 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EER27716.1 - 0.0019 17.3 0.0 0.031 13.3 0.0 2.3 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller PD40 PF07676.7 EER27716.1 - 0.0059 16.2 0.1 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat NHL PF01436.16 EER27716.1 - 0.015 15.2 0.0 21 5.2 0.0 3.9 3 1 1 4 4 4 0 NHL repeat PQQ_3 PF13570.1 EER27716.1 - 0.085 13.1 2.5 2.4 8.5 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain RHS_repeat PF05593.9 EER27716.1 - 0.09 12.9 0.3 8.7 6.6 0.1 3.0 4 0 0 4 4 4 0 RHS Repeat B9-C2 PF07162.6 EER27716.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein CoA_transf_3 PF02515.12 EER27717.1 - 1.2e-49 168.1 0.0 1.7e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Peptidase_S28 PF05577.7 EER27718.1 - 6.4e-50 169.9 0.4 1.6e-49 168.7 0.2 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Filament PF00038.16 EER27719.1 - 0.35 10.2 67.8 2 7.8 10.0 4.1 2 2 1 3 3 3 0 Intermediate filament protein adh_short_C2 PF13561.1 EER27720.1 - 2.9e-30 105.7 0.0 3.4e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER27720.1 - 4.6e-25 88.4 1.2 6.1e-25 88.0 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER27720.1 - 4.5e-13 49.2 0.5 6.3e-13 48.7 0.4 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EER27720.1 - 0.0098 14.6 1.1 0.021 13.5 0.6 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3277 PF11681.3 EER27720.1 - 0.027 13.9 0.1 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Glyco_hydro_18 PF00704.23 EER27721.1 - 1.1e-09 38.2 0.0 1.5e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.5 EER27722.1 - 2.3e-59 201.1 0.0 3.3e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase SRP54 PF00448.17 EER27723.1 - 6.2e-74 247.6 2.5 1.1e-73 246.8 1.7 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EER27723.1 - 3.1e-24 85.2 0.1 3.1e-24 85.2 0.1 4.4 3 1 1 4 4 4 1 Signal peptide binding domain SRP54_N PF02881.14 EER27723.1 - 5.5e-16 58.4 0.3 1.2e-15 57.3 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EER27723.1 - 2.5e-08 33.5 0.2 6.5e-08 32.2 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EER27723.1 - 7.1e-07 29.1 0.1 1.7e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EER27723.1 - 2.6e-05 25.0 0.0 6.3e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EER27723.1 - 4.9e-05 23.0 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EER27723.1 - 0.00029 19.6 1.1 0.0014 17.4 0.1 2.5 2 1 0 2 2 2 1 ArgK protein AAA_31 PF13614.1 EER27723.1 - 0.00075 19.4 0.0 1.1 9.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain CbiA PF01656.18 EER27723.1 - 0.001 18.5 0.4 0.0037 16.7 0.3 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EER27723.1 - 0.0011 18.9 0.1 0.0027 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EER27723.1 - 0.0012 18.5 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase SRPRB PF09439.5 EER27723.1 - 0.0015 17.7 1.1 0.99 8.5 0.1 2.9 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.7 EER27723.1 - 0.0024 17.0 0.0 0.0049 15.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ATP_bind_1 PF03029.12 EER27723.1 - 0.0031 17.0 0.7 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EER27723.1 - 0.0035 17.4 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EER27723.1 - 0.0035 17.6 0.0 0.01 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EER27723.1 - 0.006 15.9 0.1 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase 6PF2K PF01591.13 EER27723.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 EER27723.1 - 0.017 15.1 0.1 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EER27723.1 - 0.047 13.4 0.1 0.25 11.1 0.0 2.3 2 0 0 2 2 1 0 Part of AAA domain TrwB_AAD_bind PF10412.4 EER27723.1 - 0.055 12.0 0.0 0.14 10.7 0.0 1.6 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain VirE PF05272.6 EER27723.1 - 0.058 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E AAA_25 PF13481.1 EER27723.1 - 0.1 11.9 0.3 0.51 9.7 0.1 2.2 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 EER27723.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 ADP-ribosylation factor family Rrp15p PF07890.7 EER27724.1 - 9.6e-37 125.9 11.9 9.6e-37 125.9 8.3 1.7 2 0 0 2 2 2 1 Rrp15p Fer2 PF00111.22 EER27725.1 - 1.6e-12 46.9 0.9 2.4e-12 46.4 0.6 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EER27726.1 - 9.7e-10 38.0 2.2 0.83 9.4 0.0 5.3 5 1 0 5 5 5 5 Mitochondrial carrier protein Hap4_Hap_bind PF10297.4 EER27727.1 - 1.3e-08 34.3 6.1 1.3e-08 34.3 4.2 2.6 3 0 0 3 3 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EER27727.1 - 2.3e-07 30.6 14.6 8.8e-07 28.7 9.1 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EER27727.1 - 0.00024 20.8 7.2 0.00062 19.5 5.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper ADIP PF11559.3 EER27727.1 - 0.012 15.5 3.7 0.021 14.7 2.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ACCA PF03255.9 EER27727.1 - 0.063 12.8 1.0 0.14 11.7 0.7 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Prp19_bind PF06991.6 EER27727.1 - 0.22 10.7 8.5 0.35 10.0 5.9 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain IncA PF04156.9 EER27727.1 - 0.94 9.0 5.6 1.4 8.4 3.9 1.3 1 0 0 1 1 1 0 IncA protein Cauli_AT PF03233.8 EER27727.1 - 1 9.0 4.6 0.94 9.1 1.6 1.8 1 1 1 2 2 2 0 Aphid transmission protein Bap31 PF05529.7 EER27727.1 - 1.3 8.4 3.2 2.3 7.6 2.3 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Pox_A_type_inc PF04508.7 EER27727.1 - 1.4 8.9 5.3 0.39 10.6 0.1 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4407 PF14362.1 EER27727.1 - 2.2 7.1 6.5 3.5 6.5 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_Maf PF03131.12 EER27727.1 - 3 8.1 10.1 0.53 10.6 4.2 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor Methyltransf_24 PF13578.1 EER27728.1 - 3.8e-15 56.6 0.0 5.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EER27728.1 - 3.4e-07 29.5 0.0 3.2e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EER27728.1 - 0.00017 22.1 0.0 0.00052 20.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER27728.1 - 0.077 13.4 0.0 0.24 11.8 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain DUF2089 PF09862.4 EER27728.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) CmcI PF04989.7 EER27728.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Ribosomal_L19 PF01245.15 EER27729.1 - 2.3e-17 62.8 0.1 4.3e-17 61.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 AMP-binding PF00501.23 EER27731.1 - 6.6e-15 54.4 0.1 3.8e-14 51.9 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NPCC PF08058.6 EER27732.1 - 7.7e-35 119.8 0.1 7.5e-34 116.6 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore complex component CytochromB561_N PF09786.4 EER27732.1 - 0.0067 14.9 0.0 0.0078 14.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome B561, N terminal Hid1 PF12722.2 EER27733.1 - 1.6e-272 906.3 0.0 2.4e-272 905.7 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EER27733.1 - 1.9e-77 260.9 0.0 2.8e-77 260.4 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Cupin_2 PF07883.6 EER27735.1 - 6.2e-06 25.6 0.1 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain KAT11 PF08214.6 EER27736.1 - 1.7e-90 303.5 0.0 2.6e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Glyco_tranf_2_3 PF13641.1 EER27737.1 - 5e-13 49.3 0.0 1.2e-12 48.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EER27737.1 - 9.8e-11 41.2 0.0 1.8e-05 24.0 0.0 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EER27737.1 - 0.00044 19.9 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 2 Ank_2 PF12796.2 EER27738.1 - 1.6e-17 63.5 0.8 2.3e-16 59.8 0.3 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EER27738.1 - 9.3e-16 56.7 1.0 1.3e-11 43.7 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EER27738.1 - 3e-15 56.2 2.5 4.4e-09 36.6 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER27738.1 - 2.7e-14 51.8 0.6 2e-08 33.6 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EER27738.1 - 3e-12 46.3 3.3 8.5e-09 35.3 0.6 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) WW PF00397.21 EER27739.1 - 1.6e-08 34.2 1.1 4.5e-08 32.8 0.7 1.8 1 0 0 1 1 1 1 WW domain FAD_binding_2 PF00890.19 EER27740.1 - 2.8e-121 405.2 1.7 3.6e-121 404.9 1.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EER27740.1 - 9.7e-44 148.3 0.4 1.4e-43 147.7 0.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term DAO PF01266.19 EER27740.1 - 3.3e-05 22.9 0.2 8.5e-05 21.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EER27740.1 - 0.00016 20.6 2.1 0.013 14.4 1.9 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EER27740.1 - 0.00025 19.6 2.4 0.0015 17.0 0.8 2.7 4 0 0 4 4 4 1 HI0933-like protein FAD_binding_3 PF01494.14 EER27740.1 - 0.00034 19.7 0.5 0.00062 18.9 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EER27740.1 - 0.00078 18.5 0.1 0.072 12.1 0.0 3.0 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.9 EER27740.1 - 0.00082 19.3 4.4 0.001 18.9 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Hydrophobin PF01185.13 EER27741.1 - 1.4e-11 44.6 11.8 1.8e-11 44.2 8.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Alpha_GJ PF03229.8 EER27741.1 - 0.24 11.7 5.3 0.56 10.5 3.7 1.6 1 1 0 1 1 1 0 Alphavirus glycoprotein J NMO PF03060.10 EER27742.1 - 1.8e-64 218.0 0.1 2.6e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EER27742.1 - 6.6e-12 44.9 0.0 8.3e-05 21.6 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EER27742.1 - 0.002 17.0 1.0 0.0035 16.2 0.2 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NanE PF04131.9 EER27742.1 - 0.0089 15.0 0.1 0.031 13.2 0.0 2.0 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase DUF1902 PF08972.6 EER27742.1 - 0.036 13.6 0.0 0.089 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Glu_synthase PF01645.12 EER27742.1 - 0.094 11.6 1.6 0.15 10.9 0.2 1.9 1 1 1 2 2 2 0 Conserved region in glutamate synthase Sdh_cyt PF01127.17 EER27743.1 - 5.6e-24 84.2 2.9 7.9e-24 83.8 2.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Ribonucleas_3_3 PF14622.1 EER27744.1 - 3.9e-26 91.5 0.0 7.9e-26 90.5 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EER27744.1 - 0.0083 16.5 0.0 0.022 15.2 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain Adap_comp_sub PF00928.16 EER27745.1 - 1.3e-90 303.0 0.0 1.8e-90 302.6 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EER27745.1 - 1.2e-09 37.9 0.2 2e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EER27745.1 - 0.095 11.8 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain ABC2_membrane PF01061.19 EER27747.1 - 9.6e-84 279.7 50.7 4.3e-45 153.4 11.8 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EER27747.1 - 8.7e-36 123.2 0.0 9.1e-19 68.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EER27747.1 - 2e-25 88.4 0.1 1.3e-21 76.2 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EER27747.1 - 3.8e-11 42.6 38.4 7.6e-07 28.4 13.9 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EER27747.1 - 6.8e-07 29.2 0.0 3e-06 27.2 0.0 2.2 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EER27747.1 - 9.4e-06 25.7 0.0 0.02 14.8 0.0 2.8 2 1 1 3 3 2 2 AAA domain AAA_25 PF13481.1 EER27747.1 - 0.00025 20.5 0.3 0.0065 15.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EER27747.1 - 0.00084 18.8 0.3 0.0032 16.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EER27747.1 - 0.00089 18.7 0.1 0.0019 17.6 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EER27747.1 - 0.00097 19.0 0.1 0.018 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER27747.1 - 0.0012 19.5 0.0 0.0094 16.7 0.0 2.4 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EER27747.1 - 0.0014 18.2 0.9 0.52 9.9 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EER27747.1 - 0.002 18.1 0.5 0.01 15.8 0.1 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_28 PF13521.1 EER27747.1 - 0.0023 17.9 1.2 0.031 14.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 EER27747.1 - 0.0039 16.3 0.0 0.0083 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EER27747.1 - 0.011 14.9 0.0 0.76 8.9 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EER27747.1 - 0.019 15.1 0.3 0.11 12.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EER27747.1 - 0.034 13.8 0.3 1.7 8.4 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EER27747.1 - 0.062 13.6 0.2 0.3 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EER27747.1 - 0.11 11.9 0.4 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EER27747.1 - 0.32 11.3 0.0 0.32 11.3 0.0 3.2 4 0 0 4 4 3 0 AAA domain ABC_tran PF00005.22 EER27748.1 - 1.8e-48 164.3 0.1 1.8e-25 89.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EER27748.1 - 6.5e-29 101.0 49.5 1.9e-20 73.1 17.1 2.5 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EER27748.1 - 4e-21 76.2 2.6 0.0003 20.8 0.4 5.1 4 1 0 5 5 5 4 AAA domain AAA_29 PF13555.1 EER27748.1 - 5.4e-11 41.8 1.5 1.3e-05 24.6 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EER27748.1 - 3.9e-09 37.1 1.1 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EER27748.1 - 3.5e-08 32.9 3.5 0.027 13.7 0.0 3.6 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EER27748.1 - 4.5e-05 23.5 0.2 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EER27748.1 - 0.00013 21.2 1.0 0.25 10.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EER27748.1 - 0.0075 16.2 0.1 2.3 8.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EER27748.1 - 0.011 15.8 0.2 1.7 8.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EER27748.1 - 0.012 15.5 1.8 10 6.0 0.1 4.0 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EER27748.1 - 0.013 14.5 0.0 1.2 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.1 EER27748.1 - 0.02 14.3 1.6 5.1 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EER27748.1 - 0.04 13.0 0.4 3.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MutS_V PF00488.16 EER27748.1 - 0.044 13.1 0.0 3.6 6.9 0.0 2.7 3 0 0 3 3 3 0 MutS domain V FtsK_SpoIIIE PF01580.13 EER27748.1 - 0.045 13.2 0.2 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 EER27748.1 - 0.07 12.5 0.6 11 5.4 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EER27748.1 - 0.083 12.3 0.6 6.5 6.0 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EER27748.1 - 0.096 12.6 0.0 19 5.2 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EER27748.1 - 0.13 11.7 4.7 3.9 7.0 0.1 3.1 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EER27748.1 - 0.18 11.7 0.2 21 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EER27748.1 - 0.23 11.2 4.3 8.7 6.1 0.1 3.1 3 0 0 3 3 3 0 Part of AAA domain AAA_13 PF13166.1 EER27748.1 - 0.41 9.0 0.1 6.5 5.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EER27748.1 - 0.89 8.2 4.5 4.5 5.9 0.3 2.8 3 0 0 3 3 3 0 ArgK protein MFS_1 PF07690.11 EER27750.1 - 2.9e-35 121.6 52.4 2.9e-35 121.6 36.3 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER27750.1 - 9.4e-14 50.5 21.1 1.4e-13 49.9 14.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER27750.1 - 1.2e-13 50.5 12.8 1.2e-13 50.5 8.9 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter HDPD PF02924.9 EER27750.1 - 0.013 15.3 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage lambda head decoration protein D EXS PF03124.9 EER27750.1 - 0.063 12.2 2.1 0.12 11.4 1.5 1.4 1 0 0 1 1 1 0 EXS family DUF4414 PF14377.1 EER27750.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) DUF1100 PF06500.6 EER27751.1 - 1.4e-12 46.9 0.0 2e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 EER27751.1 - 1.3e-10 41.1 0.0 3.3e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER27751.1 - 3.7e-09 36.8 0.7 7e-09 35.8 0.2 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER27751.1 - 0.0024 17.1 0.0 0.0085 15.3 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family AMP-binding PF00501.23 EER27752.1 - 7.9e-80 268.2 0.0 1.3e-79 267.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EER27752.1 - 1.8e-74 250.4 0.0 3.4e-74 249.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EER27752.1 - 9.4e-48 163.1 0.0 1.7e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EER27752.1 - 1.3e-46 159.1 0.0 2.2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Condensation PF00668.15 EER27752.1 - 1.2e-45 155.6 0.5 1.7e-45 155.1 0.3 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 EER27752.1 - 3.5e-45 153.8 0.0 3e-43 147.5 0.0 3.4 2 1 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EER27752.1 - 1.2e-38 132.5 0.0 8.6e-38 129.6 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EER27752.1 - 2.4e-37 128.4 0.0 4.2e-33 114.6 0.0 3.5 2 1 0 2 2 2 2 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EER27752.1 - 3.7e-30 104.2 0.1 7.6e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EER27752.1 - 3.1e-17 62.8 0.0 9.8e-17 61.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EER27752.1 - 1.3e-13 51.0 10.1 9.9e-09 35.3 0.2 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 EER27752.1 - 1.9e-12 47.1 0.0 2.9e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 EER27752.1 - 4.4e-11 42.7 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER27752.1 - 4.6e-11 43.0 0.0 1.3e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER27752.1 - 2e-10 40.4 0.0 6.6e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EER27752.1 - 1.4e-09 38.1 0.0 4.1e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 EER27752.1 - 1e-07 32.4 0.0 1.6e-05 25.4 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 EER27752.1 - 8.7e-06 24.6 0.0 2.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 EER27752.1 - 1.3e-05 24.3 0.1 3.4e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 EER27752.1 - 9.1e-05 22.5 0.0 0.00034 20.6 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Ubie_methyltran PF01209.13 EER27752.1 - 0.00014 21.0 0.0 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EER27752.1 - 0.00057 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EER27752.1 - 0.048 12.6 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.6 EER27752.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_8 PF05148.10 EER27752.1 - 0.41 10.2 0.0 0.91 9.0 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Rota_NS35 PF02509.9 EER27752.1 - 1.5 7.4 0.0 2.9 6.5 0.0 1.3 1 0 0 1 1 1 0 Rotavirus non-structural protein 35 ADH_zinc_N PF00107.21 EER27754.1 - 4.2e-08 32.8 0.0 6.7e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER27754.1 - 0.00046 19.9 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Zn_clus PF00172.13 EER27755.1 - 0.00068 19.4 8.3 0.0013 18.6 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4061 PF13270.1 EER27755.1 - 0.062 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Peptidase_M18 PF02127.10 EER27756.1 - 5.7e-130 433.6 0.0 6.5e-130 433.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) NOB1_Zn_bind PF08772.6 EER27757.1 - 4e-32 109.8 3.6 7.7e-32 108.9 2.5 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 EER27757.1 - 0.00029 20.6 2.0 0.00029 20.6 1.4 2.2 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 EER27757.1 - 0.0022 17.4 1.5 0.0067 15.9 1.0 1.9 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Nop10p PF04135.7 EER27758.1 - 2.2e-21 75.3 0.2 2.7e-21 75.0 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family tRNA_int_endo PF01974.12 EER27759.1 - 7.7e-22 76.8 0.1 2.7e-21 75.1 0.1 1.9 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EER27759.1 - 1.2e-06 27.9 0.0 0.00028 20.3 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain S-methyl_trans PF02574.11 EER27760.1 - 9.1e-26 90.8 0.0 2.9e-25 89.2 0.0 1.9 1 1 0 1 1 1 1 Homocysteine S-methyltransferase Rad9_Rad53_bind PF08605.5 EER27761.1 - 7.8e-15 54.8 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EER27761.1 - 1.2e-06 28.5 0.0 4.1e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribosomal_L27 PF01016.14 EER27762.1 - 1e-29 102.1 0.1 1.6e-29 101.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein Scramblase PF03803.10 EER27764.1 - 6.9e-51 172.4 0.0 1.3e-26 93.0 0.0 2.2 1 1 1 2 2 2 2 Scramblase UQ_con PF00179.21 EER27765.1 - 2.5e-49 166.2 0.0 2.9e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TP6A_N PF04406.9 EER27766.1 - 4.7e-13 48.5 0.0 8.1e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Prenyltrans PF00432.16 EER27767.1 - 1.5e-33 113.9 4.7 3.6e-10 39.2 0.1 5.9 6 0 0 6 6 6 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EER27767.1 - 7.1e-29 100.0 0.0 1.2e-13 50.9 0.3 5.8 4 1 2 6 6 6 4 Prenyltransferase-like Prenyltrans_2 PF13249.1 EER27767.1 - 3.2e-26 91.9 2.3 1.7e-15 57.4 0.4 5.2 4 1 1 5 5 5 3 Prenyltransferase-like Pec_lyase PF09492.5 EER27767.1 - 1.5e-10 40.7 3.3 0.25 10.4 0.0 5.6 4 1 1 6 6 6 4 Pectic acid lyase SGS PF05002.10 EER27768.1 - 2.8e-27 94.3 2.9 9e-27 92.6 2.0 1.9 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EER27768.1 - 8e-17 61.5 0.0 1.6e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EER27768.1 - 6.5e-07 28.9 0.0 3.2e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EER27768.1 - 0.00087 18.7 0.0 0.07 12.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EER27768.1 - 0.0013 18.5 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER27768.1 - 0.087 13.5 2.2 0.91 10.2 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Bul1_N PF04425.7 EER27768.1 - 0.18 10.3 4.3 2.2 6.7 0.0 2.1 2 0 0 2 2 2 0 Bul1 N terminus Lin-8 PF03353.10 EER27768.1 - 0.77 8.9 6.0 1.4 8.0 4.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PQ-loop PF04193.9 EER27769.1 - 1.3e-41 139.9 11.2 2.4e-21 75.0 1.1 2.9 2 0 0 2 2 2 2 PQ loop repeat PgaD PF13994.1 EER27769.1 - 0.028 13.8 0.2 0.21 11.0 0.0 2.5 3 0 0 3 3 3 0 PgaD-like protein adh_short PF00106.20 EER27770.1 - 5.3e-29 101.2 0.7 7.9e-29 100.7 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER27770.1 - 4.8e-18 65.7 0.0 6.5e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER27770.1 - 6.5e-13 48.7 0.1 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EER27770.1 - 2.3e-07 30.2 0.0 2.9e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EER27770.1 - 5.9e-05 23.1 0.1 0.00037 20.5 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EER27770.1 - 0.0042 16.8 0.1 0.019 14.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EER27770.1 - 0.024 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EER27770.1 - 0.13 11.6 0.2 0.22 10.9 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family tRNA-synt_1e PF01406.14 EER27771.1 - 6.7e-117 389.9 0.0 1.1e-116 389.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EER27771.1 - 2.2e-06 26.6 0.3 0.038 12.6 0.1 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.13 EER27771.1 - 0.014 14.0 0.0 1.8 7.1 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetases class I (K) DALR_2 PF09190.6 EER27771.1 - 0.031 14.5 0.0 0.13 12.5 0.0 2.1 1 0 0 1 1 1 0 DALR domain GCD14 PF08704.5 EER27772.1 - 4.1e-62 209.8 0.1 1.2e-60 205.0 0.1 2.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EER27772.1 - 0.00052 20.0 0.0 0.00091 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER27772.1 - 0.073 13.6 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SNAPc19 PF15497.1 EER27772.1 - 4.9 7.4 6.5 0.39 10.9 0.5 2.1 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 TPR_11 PF13414.1 EER27773.1 - 9.9e-11 41.1 0.1 8.1e-10 38.2 0.0 2.3 2 0 0 2 2 2 1 TPR repeat UBA PF00627.26 EER27773.1 - 5.5e-06 26.0 0.0 2.1e-05 24.1 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 EER27773.1 - 1e-05 25.0 0.1 0.016 15.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER27773.1 - 4.9e-05 22.7 0.0 0.027 14.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EER27773.1 - 5.9e-05 23.6 1.2 0.017 15.7 0.0 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EER27773.1 - 0.0013 18.6 0.7 0.026 14.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 EER27773.1 - 0.033 13.9 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 DnaJ domain DUF1688 PF07958.6 EER27774.1 - 2.7e-181 602.6 0.0 3.1e-181 602.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Gtr1_RagA PF04670.7 EER27775.1 - 1.5e-91 305.6 0.6 1.9e-91 305.3 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EER27775.1 - 4.1e-09 35.9 0.0 1.1e-08 34.4 0.0 1.7 1 1 1 2 2 2 1 ADP-ribosylation factor family Ras PF00071.17 EER27775.1 - 1.4e-07 31.0 0.0 2.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER27775.1 - 2.3e-06 28.0 0.0 5.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EER27775.1 - 7.8e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER27775.1 - 6.4e-05 22.4 0.1 0.00013 21.4 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EER27775.1 - 0.0031 16.9 0.9 0.0095 15.4 0.3 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 EER27775.1 - 0.0099 14.8 0.1 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EER27775.1 - 0.012 15.8 0.1 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.11 EER27775.1 - 0.056 12.5 1.6 0.14 11.2 0.3 2.3 2 1 0 2 2 2 0 AIG1 family SRPRB PF09439.5 EER27775.1 - 0.076 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EER27775.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NikR_C PF08753.6 EER27775.1 - 0.11 12.4 0.0 6.4 6.7 0.0 2.6 2 0 0 2 2 2 0 NikR C terminal nickel binding domain AAA_10 PF12846.2 EER27775.1 - 0.11 11.8 0.2 0.22 10.9 0.2 1.7 1 1 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 EER27775.1 - 0.67 8.5 4.1 1.7 7.2 1.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit AA_permease PF00324.16 EER27776.1 - 5.8e-122 407.4 33.8 7.1e-122 407.1 23.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER27776.1 - 1.2e-35 122.9 35.1 1.5e-35 122.6 24.3 1.2 1 0 0 1 1 1 1 Amino acid permease RdRP PF05183.7 EER27777.1 - 4.5e-134 448.2 0.0 6e-134 447.8 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase MFS_1 PF07690.11 EER27778.1 - 1.1e-38 132.9 36.9 1.1e-38 132.9 25.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER27778.1 - 7.7e-13 47.8 13.5 1.4e-12 46.9 9.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Mem_trans PF03547.13 EER27778.1 - 0.012 13.8 0.0 0.69 8.1 0.0 2.3 1 1 1 2 2 2 0 Membrane transport protein Opi1 PF08618.5 EER27779.1 - 5e-94 315.6 2.1 9.5e-56 189.5 3.1 3.1 1 1 2 3 3 3 3 Transcription factor Opi1 DUF2359 PF10151.4 EER27779.1 - 0.0075 14.8 0.2 0.013 14.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2359) KfrA_N PF11740.3 EER27779.1 - 0.0083 16.5 0.3 0.021 15.2 0.2 1.7 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term Perilipin PF03036.11 EER27779.1 - 0.023 13.5 6.6 0.24 10.2 1.8 2.2 2 0 0 2 2 2 0 Perilipin family DUF3168 PF11367.3 EER27779.1 - 0.097 12.8 0.7 0.24 11.5 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3168) adh_short_C2 PF13561.1 EER27780.1 - 2e-28 99.7 0.5 2.9e-28 99.2 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER27780.1 - 1.8e-21 76.7 2.9 3e-21 76.0 2.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER27780.1 - 6.7e-07 29.1 3.3 3.8e-06 26.6 2.3 1.9 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EER27780.1 - 0.019 14.1 0.2 0.056 12.5 0.1 1.8 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IceA2 PF05862.6 EER27780.1 - 0.034 13.8 0.5 0.16 11.6 0.1 2.3 3 0 0 3 3 3 0 Helicobacter pylori IceA2 protein 3HCDH_N PF02737.13 EER27780.1 - 0.051 13.2 0.2 0.078 12.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EER27780.1 - 0.18 11.6 1.3 0.42 10.4 0.9 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LIP PF03583.9 EER27781.1 - 5.3e-82 275.2 0.0 6.8e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 EER27781.1 - 0.00018 21.4 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER27781.1 - 0.12 11.5 0.2 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Voldacs PF03517.8 EER27782.1 - 2.2e-31 108.4 0.1 2.2e-31 108.4 0.1 1.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling Metallophos PF00149.23 EER27784.1 - 8.7e-42 142.7 0.6 1.3e-41 142.2 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1647 PF07801.6 EER27784.1 - 0.12 11.8 1.4 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) iPGM_N PF06415.8 EER27785.1 - 0.06 12.6 0.1 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) Abhydrolase_2 PF02230.11 EER27786.1 - 1.8e-15 57.0 0.0 2.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EER27786.1 - 2.6e-05 24.2 0.1 4.6e-05 23.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27786.1 - 3.4e-05 23.6 0.0 6.7e-05 22.6 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EER27786.1 - 0.037 13.4 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) EXS PF03124.9 EER27787.1 - 3.8e-80 269.5 19.8 3.8e-73 246.4 7.7 2.1 1 1 1 2 2 2 2 EXS family SPX PF03105.14 EER27787.1 - 3.4e-59 200.8 0.0 6.8e-59 199.8 0.0 1.5 1 0 0 1 1 1 1 SPX domain Peptidase_S8 PF00082.17 EER27788.1 - 9.4e-53 179.1 10.1 1.4e-52 178.6 7.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER27788.1 - 2e-20 73.1 0.3 4.1e-20 72.1 0.2 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.13 EER27789.1 - 2e-109 365.2 0.0 3.6e-109 364.3 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EER27789.1 - 1.7e-10 40.6 1.8 1.8e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EER27789.1 - 2.8e-08 34.1 0.0 6.6e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 EER27789.1 - 6.5e-06 25.8 2.5 0.16 11.9 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Transaldolase PF00923.14 EER27790.1 - 3.2e-94 315.2 0.3 3.7e-94 315.0 0.2 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 EER27790.1 - 0.077 12.2 0.1 0.13 11.4 0.1 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Pkinase PF00069.20 EER27791.1 - 6.9e-09 35.2 0.0 1.9e-08 33.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27791.1 - 0.0086 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EER27791.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EER27791.1 - 0.024 14.3 0.0 0.091 12.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sod_Cu PF00080.15 EER27792.1 - 4.3e-45 153.3 5.3 4.9e-45 153.1 3.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF1522 PF07482.6 EER27792.1 - 0.022 14.8 1.7 0.14 12.2 0.4 2.2 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1522) COXG PF06240.8 EER27792.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) SNase PF00565.12 EER27793.1 - 5.8e-81 267.8 0.4 7e-26 90.6 0.0 5.8 6 0 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EER27793.1 - 1.9e-26 92.3 0.0 1.2e-25 89.7 0.0 2.1 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EER27793.1 - 0.00081 18.5 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) CRAL_TRIO PF00650.15 EER27794.1 - 1e-24 86.8 0.0 1.5e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EER27794.1 - 2.6e-09 37.0 0.1 5.4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AT_hook PF02178.14 EER27795.1 - 3.5e-09 35.2 59.6 0.018 14.6 1.8 6.9 6 0 0 6 6 6 6 AT hook motif DUF1620 PF07774.8 EER27796.1 - 6e-74 247.9 0.0 1.1e-73 247.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EER27796.1 - 3.2e-24 85.6 12.4 1.3e-20 73.9 3.4 3.4 3 1 0 4 4 4 2 PQQ-like domain PQQ PF01011.16 EER27796.1 - 2.5e-07 29.8 1.4 10 5.8 0.0 7.5 8 0 0 8 8 8 2 PQQ enzyme repeat PQQ_3 PF13570.1 EER27796.1 - 0.0096 16.1 4.1 9.6 6.6 0.5 5.2 5 0 0 5 5 5 1 PQQ-like domain Peptidase_M35 PF02102.10 EER27797.1 - 7.4e-98 327.5 4.4 8.7e-98 327.2 3.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EER27797.1 - 1.3e-10 41.9 0.5 2.6e-10 40.9 0.1 1.7 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase DUF1479 PF07350.7 EER27798.1 - 4.4e-166 552.4 0.0 5.1e-166 552.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) SAB PF04382.8 EER27798.1 - 0.024 14.3 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 SAB domain PhyH PF05721.8 EER27798.1 - 0.087 12.8 0.0 1.9 8.4 0.0 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) adh_short PF00106.20 EER27799.1 - 1.6e-18 67.1 0.0 2.3e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER27799.1 - 1.7e-10 41.0 0.0 2.3e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER27799.1 - 2.3e-08 33.9 0.0 7.5e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EER27799.1 - 0.0045 16.4 0.0 0.041 13.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Aa_trans PF01490.13 EER27800.1 - 4.3e-92 308.7 17.4 7e-92 308.0 12.0 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SK_channel PF03530.9 EER27800.1 - 0.11 12.3 0.3 0.11 12.3 0.2 2.5 3 1 0 3 3 3 0 Calcium-activated SK potassium channel YfhO PF09586.5 EER27800.1 - 0.2 9.6 4.7 0.34 8.8 3.3 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO GWT1 PF06423.7 EER27800.1 - 0.8 9.7 6.6 5.5 7.0 2.4 3.2 3 1 1 4 4 4 0 GWT1 Bax1-I PF01027.15 EER27801.1 - 5.6e-49 166.5 32.5 6.6e-49 166.3 22.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 CDC50 PF03381.10 EER27801.1 - 0.081 12.0 0.1 0.17 11.0 0.0 1.7 2 0 0 2 2 2 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Orbi_NS3 PF01616.11 EER27801.1 - 0.18 10.7 3.8 0.85 8.5 0.2 2.4 2 0 0 2 2 2 0 Orbivirus NS3 DUF1118 PF06549.7 EER27801.1 - 0.27 11.3 2.4 1.1 9.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1118) Spore_YhaL PF14147.1 EER27801.1 - 0.34 10.3 0.1 0.34 10.3 0.1 2.1 2 0 0 2 2 2 0 Sporulation protein YhaL 7TMR-DISM_7TM PF07695.6 EER27801.1 - 2.5 7.7 34.7 1.7 8.2 11.2 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling UQ_con PF00179.21 EER27803.1 - 6.4e-39 132.5 0.0 8.2e-39 132.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC_tran PF00005.22 EER27804.1 - 5.2e-54 182.2 0.0 1.2e-30 106.6 0.0 3.0 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EER27804.1 - 1.2e-44 152.7 28.3 6.2e-23 81.5 5.2 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EER27804.1 - 1e-08 35.5 0.6 7.3e-05 22.8 0.1 3.6 3 1 0 3 3 2 2 AAA domain SMC_N PF02463.14 EER27804.1 - 8e-07 28.5 9.2 0.068 12.3 2.4 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EER27804.1 - 2.1e-06 28.1 1.8 0.0014 19.0 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EER27804.1 - 2.2e-05 24.0 1.2 0.006 16.0 0.0 2.9 2 1 1 3 3 3 1 AAA-like domain AAA_25 PF13481.1 EER27804.1 - 4.7e-05 22.8 0.1 0.11 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EER27804.1 - 5.1e-05 23.3 1.4 0.04 13.8 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EER27804.1 - 0.00012 21.5 0.4 0.32 10.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EER27804.1 - 0.00016 20.6 0.0 0.014 14.2 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF87 PF01935.12 EER27804.1 - 0.00025 20.9 1.7 0.0021 17.9 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EER27804.1 - 0.00079 18.5 0.2 0.85 8.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 EER27804.1 - 0.0015 19.3 0.5 2.6 8.8 0.0 3.2 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EER27804.1 - 0.002 18.0 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EER27804.1 - 0.0021 17.2 0.2 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 TrwB_AAD_bind PF10412.4 EER27804.1 - 0.0029 16.3 0.4 0.86 8.1 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 EER27804.1 - 0.0031 17.6 1.6 3.9 7.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain Miro PF08477.8 EER27804.1 - 0.0036 17.8 0.3 4 7.9 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EER27804.1 - 0.017 15.3 1.4 7.5 6.8 0.1 3.0 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EER27804.1 - 0.018 14.4 0.1 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EER27804.1 - 0.026 14.1 0.3 6.1 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EER27804.1 - 0.032 13.9 0.1 3.8 7.2 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EER27804.1 - 0.064 12.6 0.9 4.7 6.6 0.0 2.9 4 0 0 4 4 2 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EER27804.1 - 0.12 12.5 0.1 26 5.0 0.0 3.2 3 0 0 3 3 2 0 RNA helicase cobW PF02492.14 EER27804.1 - 0.13 11.6 1.1 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EER27804.1 - 0.14 11.7 0.7 18 4.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EER27804.1 - 0.17 12.1 1.7 13 6.0 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EER27804.1 - 0.17 11.6 0.0 6.1 6.6 0.0 2.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Dynamin_N PF00350.18 EER27804.1 - 4.2 7.1 5.4 14 5.4 0.0 2.9 3 0 0 3 3 2 0 Dynamin family GCD14 PF08704.5 EER27805.1 - 0.13 11.7 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit AAA_12 PF13087.1 EER27806.1 - 1.5e-32 112.5 0.0 2.5e-32 111.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EER27806.1 - 8e-24 84.5 0.0 8.5e-23 81.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EER27806.1 - 2.8e-11 43.0 0.2 7.9e-11 41.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EER27806.1 - 6.3e-09 35.6 0.0 1.3e-06 28.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EER27806.1 - 0.0002 20.9 0.0 0.67 9.4 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EER27806.1 - 0.015 14.2 0.1 0.57 9.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EER27806.1 - 0.019 14.1 0.0 0.045 12.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.24 EER27806.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.10 EER27806.1 - 0.096 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EER27806.1 - 0.1 11.8 0.0 0.53 9.5 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain WD40 PF00400.27 EER27807.1 - 2.8e-19 68.1 3.7 0.0048 16.7 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat PRP38 PF03371.10 EER27809.1 - 6.1e-68 227.8 0.0 7.3e-68 227.5 0.0 1.0 1 0 0 1 1 1 1 PRP38 family DUF3445 PF11927.3 EER27810.1 - 7.4e-75 251.5 0.0 9.4e-75 251.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_90 PF05686.7 EER27811.1 - 4.2e-13 48.7 0.5 3.2e-12 45.8 0.4 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 90 DUF3333 PF11812.3 EER27811.1 - 1.2 9.1 3.7 17 5.3 1.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) Asp PF00026.18 EER27812.1 - 0.0085 15.3 0.4 0.015 14.5 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease WSC PF01822.14 EER27813.1 - 1.1e-10 41.2 5.5 2.7e-10 40.0 3.8 1.7 1 0 0 1 1 1 1 WSC domain Protocadherin PF08374.6 EER27813.1 - 0.012 15.3 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 Protocadherin Herpes_gE PF02480.11 EER27813.1 - 0.013 13.7 0.0 0.02 13.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1179 PF06678.6 EER27813.1 - 0.037 14.3 0.1 13 6.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) TMEM154 PF15102.1 EER27813.1 - 0.071 12.8 4.1 0.25 11.0 2.8 1.9 1 1 0 1 1 1 0 TMEM154 protein family MFS_1 PF07690.11 EER27814.1 - 5.8e-27 94.3 47.0 7.1e-27 94.0 32.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER27814.1 - 0.027 13.0 32.8 0.0096 14.5 5.4 2.4 1 1 0 2 2 2 0 Sugar (and other) transporter p450 PF00067.17 EER27816.1 - 4.3e-39 134.3 0.0 1.4e-33 116.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Zn_clus PF00172.13 EER27817.1 - 2.3e-11 43.4 8.5 4e-11 42.6 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EER27817.1 - 3e-08 32.8 0.0 5.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1133 PF06576.6 EER27817.1 - 0.00058 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1133) NAD_binding_6 PF08030.7 EER27817.1 - 0.13 12.1 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain HNH_2 PF13391.1 EER27819.1 - 3.7e-12 45.8 0.0 8.4e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease IMS PF00817.15 EER27821.1 - 2.1e-36 124.9 0.0 1.6e-21 76.6 0.0 2.4 2 0 0 2 2 2 2 impB/mucB/samB family IMS_C PF11799.3 EER27821.1 - 6e-16 58.5 0.0 1.4e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EER27821.1 - 0.03 14.3 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif ABC1 PF03109.11 EER27822.1 - 1e-21 77.1 0.3 6.5e-21 74.5 0.1 2.2 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EER27822.1 - 0.016 14.9 1.0 0.1 12.3 0.7 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family GST_N_3 PF13417.1 EER27823.1 - 1.1e-16 60.7 0.0 2.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EER27823.1 - 9.8e-06 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER27823.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EER27823.1 - 0.057 13.4 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DDOST_48kD PF03345.9 EER27826.1 - 1.4e-162 541.0 0.0 1.6e-162 540.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pet191_N PF10203.4 EER27827.1 - 1.9e-27 95.0 4.9 2.4e-27 94.7 3.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 EER27827.1 - 0.034 13.7 0.1 0.091 12.3 0.0 1.7 1 0 0 1 1 1 0 PAN-like domain COBRA PF04833.10 EER27827.1 - 0.17 11.6 1.1 0.2 11.3 0.7 1.3 1 1 0 1 1 1 0 COBRA-like protein Cmc1 PF08583.5 EER27827.1 - 0.34 10.7 3.4 8.6 6.2 0.2 2.4 1 1 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Abhydro_lipase PF04083.11 EER27828.1 - 1.5e-22 78.6 0.2 3.8e-22 77.3 0.0 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EER27828.1 - 4.3e-17 62.4 0.4 6.6e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EER27828.1 - 5.1e-06 26.5 0.0 9.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER27828.1 - 3.6e-05 23.5 0.0 0.0001 22.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EER27828.1 - 0.00013 21.4 0.0 0.043 13.2 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Ras PF00071.17 EER27829.1 - 4.5e-52 175.7 0.0 5.4e-52 175.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER27829.1 - 1.6e-19 70.5 0.0 2.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER27829.1 - 1.5e-11 43.8 0.0 1.8e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EER27829.1 - 1.7e-07 30.8 0.0 1.4e-06 27.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EER27829.1 - 4.3e-06 26.6 0.0 7.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EER27829.1 - 0.00012 22.1 0.1 0.19 11.6 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EER27829.1 - 0.0016 18.5 0.4 0.016 15.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain SRPRB PF09439.5 EER27829.1 - 0.014 14.6 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EER27829.1 - 0.042 12.9 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.1 EER27829.1 - 0.068 12.5 0.1 0.23 10.8 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EER27829.1 - 0.09 12.2 0.0 0.22 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.12 EER27829.1 - 0.091 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein UPF0561 PF10573.4 EER27829.1 - 1 9.2 5.2 1.7 8.4 3.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Carboxyl_trans PF01039.17 EER27830.1 - 2.9e-145 484.3 0.1 3.9e-145 483.9 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EER27830.1 - 0.026 13.7 0.1 3.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) Acyl-CoA_dh_1 PF00441.19 EER27831.1 - 4.9e-39 133.8 0.5 7.8e-39 133.1 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EER27831.1 - 8.2e-32 110.1 0.1 1.5e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EER27831.1 - 6.5e-21 73.6 0.3 1.4e-20 72.4 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EER27831.1 - 8.4e-15 55.2 0.1 1.4e-14 54.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EER27831.1 - 8.8e-05 22.0 0.3 0.00049 19.5 0.2 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal CPSase_L_D2 PF02786.12 EER27833.1 - 1.5e-75 253.1 0.0 2.4e-75 252.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EER27833.1 - 4e-34 116.7 0.0 9e-34 115.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EER27833.1 - 4.9e-33 113.5 0.0 1.3e-32 112.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EER27833.1 - 1.6e-19 70.3 0.0 3.7e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EER27833.1 - 1.6e-18 66.0 0.6 3.9e-18 64.8 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EER27833.1 - 1.2e-11 44.4 0.0 2.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EER27833.1 - 5.6e-11 41.7 0.0 2.6e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EER27833.1 - 3.1e-08 33.1 0.0 5.4e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EER27833.1 - 1.3e-05 24.7 0.0 0.0097 15.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EER27833.1 - 2.5e-05 24.1 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EER27833.1 - 0.00013 21.5 0.0 0.00078 18.9 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 EER27833.1 - 0.00032 20.9 0.0 0.04 14.2 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EER27833.1 - 0.0025 17.3 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD PF00529.15 EER27833.1 - 0.012 14.9 0.1 3.9 6.7 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 EER27833.1 - 0.02 14.5 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein ATPgrasp_ST PF14397.1 EER27833.1 - 0.031 13.3 0.2 0.068 12.2 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp adh_short_C2 PF13561.1 EER27834.1 - 3.8e-27 95.5 0.0 6.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER27834.1 - 2.5e-21 76.2 1.1 3.6e-21 75.7 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER27834.1 - 1.7e-12 47.4 0.5 2.5e-12 46.8 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EER27834.1 - 0.0013 18.1 0.1 0.0027 17.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_2 PF12796.2 EER27835.1 - 1.1e-50 169.8 3.0 2.9e-16 59.5 0.1 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EER27835.1 - 2.1e-34 115.6 0.9 7.3e-09 35.0 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EER27835.1 - 2e-29 100.9 0.5 2.3e-10 40.3 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EER27835.1 - 3.1e-28 97.6 0.7 5.2e-08 33.1 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER27835.1 - 3.7e-27 91.6 0.1 3.4e-05 23.6 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat F-box PF00646.28 EER27835.1 - 0.043 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 F-box domain gag-asp_proteas PF13975.1 EER27835.1 - 0.045 13.5 0.3 19 5.1 0.0 3.7 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease HEM4 PF02602.10 EER27835.1 - 0.054 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD MARVEL PF01284.18 EER27837.1 - 8e-08 32.2 8.0 1.3e-07 31.5 5.6 1.4 1 1 0 1 1 1 1 Membrane-associating domain Tetraspannin PF00335.15 EER27837.1 - 0.0021 17.3 1.8 0.003 16.8 1.3 1.1 1 0 0 1 1 1 1 Tetraspanin family TrbC PF04956.8 EER27837.1 - 0.032 14.2 3.4 0.064 13.2 0.1 2.4 2 1 0 2 2 2 0 TrbC/VIRB2 family DUF2456 PF10445.4 EER27837.1 - 0.8 9.6 4.8 1.8 8.5 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2456) PHD PF00628.24 EER27839.1 - 9.3e-10 38.0 1.3 9.3e-10 38.0 0.9 1.8 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EER27839.1 - 0.0025 17.1 2.4 0.004 16.4 1.6 1.4 1 0 0 1 1 1 1 PHD-finger eIF-5a PF01287.15 EER27840.1 - 0.0011 18.9 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF3248 PF11609.3 EER27841.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3248) Peptidase_M28 PF04389.12 EER27842.1 - 9.8e-27 93.8 0.1 2.5e-26 92.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EER27842.1 - 2.3e-05 23.9 0.0 4.6e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 SRR1 PF07985.7 EER27844.1 - 8e-13 48.1 0.0 1.4e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 SRR1 Isochorismatase PF00857.15 EER27845.1 - 1.1e-42 145.9 0.0 1.2e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Glyco_hydro_17 PF00332.13 EER27846.1 - 8.5e-07 28.3 2.0 2e-06 27.0 0.6 2.0 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Ndc80_HEC PF03801.8 EER27847.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family Rubredoxin PF00301.15 EER27849.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Rubredoxin zf-DHHC PF01529.15 EER27850.1 - 1.9e-24 86.0 10.2 1.3e-23 83.2 7.2 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase FAD_binding_3 PF01494.14 EER27852.1 - 1.2e-19 70.5 2.3 1.3e-14 54.0 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EER27852.1 - 1.6e-09 37.6 0.6 4.3e-09 36.2 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EER27852.1 - 6.5e-09 35.1 6.5 7.5e-08 31.6 2.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EER27852.1 - 2.3e-07 30.2 0.3 3.5e-07 29.6 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EER27852.1 - 1.3e-06 28.4 1.7 2.5e-06 27.5 1.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EER27852.1 - 1.3e-05 24.2 5.4 4e-05 22.6 2.9 2.0 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.17 EER27852.1 - 2.4e-05 23.3 1.1 3.9e-05 22.7 0.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EER27852.1 - 4.8e-05 23.6 0.5 4.8e-05 23.6 0.3 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EER27852.1 - 6.6e-05 21.9 0.2 9.3e-05 21.5 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EER27852.1 - 0.0028 16.1 2.2 0.0049 15.3 1.5 1.3 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EER27852.1 - 0.0051 16.3 0.1 0.011 15.3 0.1 1.8 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EER27852.1 - 0.0082 15.8 0.5 0.015 15.0 0.4 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 EER27852.1 - 0.011 14.3 1.9 0.086 11.4 0.8 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EER27852.1 - 0.012 14.7 0.2 0.024 13.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EER27852.1 - 0.017 15.1 0.2 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EER27852.1 - 0.021 13.8 1.2 0.14 11.1 0.2 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.11 EER27852.1 - 0.065 12.6 1.5 0.15 11.5 1.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EER27852.1 - 0.14 11.7 1.4 0.3 10.7 0.9 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EER27853.1 - 4e-14 52.1 0.0 8.7e-14 51.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER27853.1 - 0.00034 20.4 7.6 0.00063 19.6 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nucleoplasmin PF03066.10 EER27853.1 - 0.33 10.4 4.1 0.58 9.6 2.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EER27853.1 - 2.1 8.6 6.2 4.8 7.4 4.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_60s PF00428.14 EER27853.1 - 2.2 8.7 16.9 0.029 14.7 5.5 2.6 3 0 0 3 3 3 0 60s Acidic ribosomal protein zf-C3H1 PF10650.4 EER27854.1 - 5.6e-09 35.3 2.2 8.8e-09 34.6 1.5 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Myosin_head PF00063.16 EER27855.1 - 5.1e-248 824.6 0.0 5.1e-248 824.6 0.0 2.8 5 0 0 5 5 5 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EER27855.1 - 3.4e-31 107.8 280.0 5.5e-22 77.3 57.1 6.1 3 2 3 6 6 6 5 Myosin tail Reo_sigmaC PF04582.7 EER27855.1 - 0.00016 20.9 3.7 0.00016 20.9 2.6 10.1 2 2 6 11 11 11 6 Reovirus sigma C capsid protein Myosin_N PF02736.14 EER27855.1 - 0.0061 16.1 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EER27855.1 - 0.061 13.0 0.0 0.19 11.4 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain BPL_C PF02237.12 EER27855.1 - 0.092 12.4 0.2 0.8 9.4 0.1 2.6 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Abhydrolase_1 PF00561.15 EER27856.1 - 1.1e-18 67.6 0.1 3.5e-18 65.9 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EER27856.1 - 2.2e-10 40.8 1.7 6e-09 36.1 1.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EER27856.1 - 0.00018 20.9 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase ThiF PF00899.16 EER27857.1 - 1.1e-34 119.1 0.0 1.7e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Glyco_hydro_17 PF00332.13 EER27857.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 TrkA_N PF02254.13 EER27857.1 - 0.14 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EER27857.1 - 0.15 11.0 0.1 6.3 5.6 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase Metallophos PF00149.23 EER27858.1 - 7.8e-10 38.4 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER27858.1 - 3.8e-07 30.0 0.0 6.6e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EER27858.1 - 0.027 13.6 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily MARVEL PF01284.18 EER27859.1 - 1.9e-20 73.1 11.1 2.4e-20 72.8 7.7 1.1 1 0 0 1 1 1 1 Membrane-associating domain PepSY_TM_2 PF13703.1 EER27859.1 - 0.15 12.2 0.3 0.15 12.2 0.2 2.9 2 1 1 3 3 3 0 PepSY-associated TM helix SCAMP PF04144.8 EER27859.1 - 1.5 8.6 8.5 21 4.9 5.9 2.2 1 1 0 1 1 1 0 SCAMP family DUF4336 PF14234.1 EER27860.1 - 5.5e-16 58.5 0.1 4.8e-12 45.6 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Nse4_C PF08743.5 EER27861.1 - 2.1e-34 117.4 0.0 6.3e-34 115.8 0.0 1.9 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EER27861.1 - 3e-17 62.1 0.1 9.9e-17 60.5 0.1 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Metal_resist PF13801.1 EER27861.1 - 0.028 14.4 8.2 0.33 10.9 1.0 3.4 3 1 0 3 3 3 0 Heavy-metal resistance PI3Ka PF00613.15 EER27862.1 - 2.2e-61 206.2 0.8 4.8e-61 205.1 0.6 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EER27862.1 - 4.1e-44 150.8 0.0 1.6e-42 145.5 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EER27862.1 - 5.5e-29 100.7 0.0 9.9e-29 99.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 EER27862.1 - 0.0012 18.6 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain HEAT_2 PF13646.1 EER27862.1 - 0.042 14.1 0.4 1 9.7 0.1 2.8 2 0 0 2 2 2 0 HEAT repeats MMR_HSR1 PF01926.18 EER27863.1 - 3.1e-12 46.4 0.0 7.6e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EER27863.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EER27863.1 - 0.0062 15.8 0.0 0.013 14.7 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EER27863.1 - 0.034 14.6 0.0 0.095 13.2 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EER27863.1 - 0.043 13.6 0.0 0.28 10.9 0.0 2.2 1 1 1 2 2 2 0 Dynamin family DBP10CT PF08147.7 EER27863.1 - 0.087 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 DBP10CT (NUC160) domain Isy1 PF06246.7 EER27864.1 - 4.9e-85 284.9 0.1 9.3e-85 284.0 0.0 1.4 1 1 0 1 1 1 1 Isy1-like splicing family Gly_transf_sug PF04488.10 EER27866.1 - 1.1e-12 48.1 0.0 2.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EER27866.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Pkinase PF00069.20 EER27867.1 - 3.4e-64 216.5 0.0 4.2e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27867.1 - 2.3e-33 115.3 0.0 2.9e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER27867.1 - 0.00052 19.0 0.0 0.00083 18.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER27867.1 - 0.006 16.3 0.0 0.21 11.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER27867.1 - 0.077 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP-synt_C PF00137.16 EER27868.1 - 1.2e-27 95.6 32.3 7.5e-16 57.8 7.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CNH PF00780.17 EER27869.1 - 2.2e-81 273.2 0.0 1.6e-80 270.5 0.0 2.0 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EER27869.1 - 2.5e-40 137.5 0.0 5.2e-40 136.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EER27869.1 - 4.3e-39 134.2 0.1 7.2e-39 133.5 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EER27869.1 - 7.6e-14 51.2 0.0 2.1e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Septin PF00735.13 EER27870.1 - 1.5e-107 358.8 0.2 2.8e-107 357.9 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EER27870.1 - 6e-05 22.9 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EER27870.1 - 0.0021 17.9 5.1 0.69 9.7 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EER27870.1 - 0.0024 17.0 0.2 0.0061 15.7 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EER27870.1 - 0.0047 16.3 0.0 0.15 11.5 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EER27870.1 - 0.022 13.8 0.0 0.054 12.5 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 EER27870.1 - 0.028 14.8 0.0 0.081 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EER27870.1 - 0.052 13.7 0.2 0.16 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EER27870.1 - 0.13 12.5 0.5 1.4 9.2 0.0 2.6 2 1 0 2 2 2 0 ABC transporter FMN_bind PF04205.9 EER27870.1 - 0.18 11.9 0.4 0.54 10.4 0.0 1.9 2 0 0 2 2 2 0 FMN-binding domain DUF3653 PF12375.3 EER27870.1 - 0.28 11.4 1.7 5.5 7.2 0.2 2.7 2 1 0 2 2 2 0 Phage protein AAA_17 PF13207.1 EER27870.1 - 0.96 10.2 7.6 0.42 11.4 0.2 2.9 2 2 0 2 2 2 0 AAA domain APG6 PF04111.7 EER27870.1 - 1.6 7.6 7.9 2.5 7.0 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EER27870.1 - 5.9 4.6 5.9 10 3.8 4.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WD40 PF00400.27 EER27871.1 - 1.6e-05 24.6 2.9 0.066 13.1 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Nbas_N PF15492.1 EER27871.1 - 0.026 13.6 0.0 1.3 8.0 0.0 2.3 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.17 EER27872.1 - 9.9e-20 69.9 0.0 2.4e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER27872.1 - 1.4e-12 47.4 0.0 2.5e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER27872.1 - 4.7e-06 26.3 0.0 8.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sigma70_r1_2 PF00140.15 EER27872.1 - 0.053 13.2 2.1 0.15 11.7 0.9 2.2 1 1 1 2 2 2 0 Sigma-70 factor, region 1.2 OB_RNB PF08206.6 EER27872.1 - 0.081 12.4 0.2 0.56 9.7 0.0 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain SelP_N PF04592.9 EER27872.1 - 1.7 7.9 14.4 10 5.4 7.5 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region MRI PF15325.1 EER27872.1 - 5.5 8.0 6.7 1.6 9.7 1.7 2.2 1 1 1 2 2 2 0 Modulator of retrovirus infection DLIC PF05783.6 EER27873.1 - 4e-36 124.7 3.7 2e-32 112.5 0.0 3.8 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) Myb_CC_LHEQLE PF14379.1 EER27873.1 - 0.0053 16.3 3.1 0.012 15.2 2.1 1.5 1 0 0 1 1 1 1 MYB-CC type transfactor, LHEQLE motif Peptidase_S9 PF00326.16 EER27874.1 - 9.1e-49 165.5 0.0 1.5e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EER27874.1 - 1.5e-08 34.5 0.0 3.8e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EER27874.1 - 4e-06 26.3 0.1 0.29 10.8 0.0 4.0 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EER27874.1 - 0.0077 14.8 0.1 0.78 8.2 0.0 3.1 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_C12 PF01088.16 EER27875.1 - 5.7e-50 169.4 0.0 6.9e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Y_phosphatase3 PF13350.1 EER27876.1 - 5e-50 169.9 0.0 6.8e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EER27876.1 - 2.7e-17 62.6 0.0 8.8e-16 57.7 0.0 2.5 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EER27876.1 - 5.3e-05 22.6 0.0 8.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EER27876.1 - 0.0063 15.8 0.0 0.0084 15.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EER27876.1 - 0.037 14.0 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Spermine_synth PF01564.12 EER27877.1 - 8.4e-08 31.4 0.0 1.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EER27877.1 - 0.024 15.2 0.0 0.042 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.16 EER27877.1 - 0.042 13.7 0.0 0.089 12.6 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF2962 PF11176.3 EER27877.1 - 0.056 13.0 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) DUF2052 PF09747.4 EER27878.1 - 7e-32 110.8 14.3 2.2e-31 109.1 9.9 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Pkinase PF00069.20 EER27879.1 - 1.8e-56 191.1 0.0 2.4e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27879.1 - 5.7e-27 94.4 0.0 2.1e-26 92.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER27879.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AMP-binding PF00501.23 EER27880.1 - 4.4e-66 222.9 0.2 5.4e-66 222.6 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER27880.1 - 6.1e-11 43.1 0.1 4.8e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF2408 PF10303.4 EER27881.1 - 0.026 14.6 2.6 1.6 8.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) SH3_1 PF00018.23 EER27883.1 - 2.1e-09 36.6 0.7 3.4e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EER27883.1 - 5.5e-08 32.2 0.0 5.4e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EER27883.1 - 5.6e-07 28.9 0.0 1.7e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain Response_reg PF00072.19 EER27884.1 - 6e-21 74.5 0.0 4.1e-14 52.5 0.0 2.4 1 1 1 2 2 2 2 Response regulator receiver domain Terminase_1 PF03354.10 EER27884.1 - 0.37 9.1 0.0 7.8 4.7 0.0 2.0 2 0 0 2 2 2 0 Phage Terminase Bot1p PF12298.3 EER27885.1 - 4.3e-55 186.3 0.6 4.3e-55 186.3 0.4 2.0 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein DUF2533 PF10752.4 EER27885.1 - 0.015 15.6 0.2 0.06 13.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) RRM_1 PF00076.17 EER27886.1 - 6.9e-15 54.4 0.0 1e-11 44.3 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER27886.1 - 3.7e-08 33.2 0.0 8.6e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_7 PF13508.1 EER27887.1 - 1.5e-09 37.8 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER27887.1 - 1.1e-06 28.5 0.1 1.7e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EER27887.1 - 2.9e-06 27.3 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER27887.1 - 1.8e-05 24.4 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EER27887.1 - 6.4e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S16 PF00886.14 EER27889.1 - 2.1e-25 88.1 0.0 2.8e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 EER27890.1 - 7.4e-37 126.5 0.0 9.7e-37 126.1 0.0 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.20 EER27890.1 - 0.046 12.9 0.0 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme PUL PF08324.6 EER27891.1 - 1.2e-54 184.8 4.7 1.6e-54 184.4 3.2 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EER27891.1 - 4.8e-44 149.0 0.5 7.9e-44 148.3 0.3 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EER27891.1 - 4e-41 137.4 19.6 4e-07 29.6 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat WD40 PF00400.27 EER27892.1 - 4.6e-31 105.5 11.3 1.6e-09 37.2 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EER27892.1 - 0.0012 17.0 1.4 0.64 8.0 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Me-amine-dh_H PF06433.6 EER27892.1 - 0.12 10.9 0.0 6.4 5.3 0.0 2.1 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) RRM_1 PF00076.17 EER27893.1 - 3.8e-18 64.8 0.0 6.2e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER27893.1 - 1.2e-11 44.3 0.0 2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EER27893.1 - 3.9e-07 30.4 5.8 3.9e-07 30.4 4.0 3.4 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EER27893.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CH PF00307.26 EER27894.1 - 3.3e-35 120.3 0.1 3.1e-18 65.7 0.0 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EER27894.1 - 1.2e-27 95.6 0.1 3.1e-27 94.3 0.1 1.8 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EER27894.1 - 7.1e-10 38.4 0.3 3e-06 26.7 0.0 2.9 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_8 PF13833.1 EER27894.1 - 0.00055 19.4 0.3 0.0031 17.0 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EER27894.1 - 0.0021 17.7 1.1 0.011 15.5 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EER27894.1 - 0.0064 15.7 0.1 0.061 12.6 0.0 2.7 2 0 0 2 2 2 1 EF hand Spectrin PF00435.16 EER27894.1 - 0.029 14.6 9.7 0.59 10.4 0.0 2.8 3 0 0 3 3 3 0 Spectrin repeat DUF1943 PF09172.6 EER27894.1 - 0.053 12.3 1.0 0.079 11.8 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) G-alpha PF00503.15 EER27895.1 - 1.6e-132 441.9 1.5 2e-132 441.5 1.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EER27895.1 - 3.9e-16 58.7 0.5 9.6e-11 41.2 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EER27895.1 - 8.6e-05 22.0 0.0 0.00037 19.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EER27895.1 - 0.0011 19.4 0.1 2.5 8.6 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EER27895.1 - 0.0041 16.3 3.6 0.11 11.6 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EER27895.1 - 0.0091 15.5 0.1 0.024 14.1 0.1 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EER27895.1 - 0.016 14.6 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 EER27895.1 - 0.059 12.1 0.0 0.094 11.4 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 EER27895.1 - 0.078 12.9 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mog1 PF04603.7 EER27895.1 - 0.11 12.5 0.3 1.2 9.0 0.1 2.5 3 0 0 3 3 3 0 Ran-interacting Mog1 protein FtsK_SpoIIIE PF01580.13 EER27895.1 - 0.11 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Use1 PF09753.4 EER27896.1 - 1.2e-09 37.9 0.3 2e-09 37.2 0.2 1.4 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF745 PF05335.8 EER27896.1 - 0.0017 17.9 5.6 0.16 11.4 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF745) DUF2730 PF10805.3 EER27896.1 - 0.035 13.8 0.2 0.035 13.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) YliH PF10799.3 EER27896.1 - 0.058 13.0 0.1 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) DivIC PF04977.10 EER27896.1 - 1.3 8.5 4.2 0.25 10.8 0.3 1.7 2 0 0 2 2 2 0 Septum formation initiator AMP-binding PF00501.23 EER27897.1 - 2e-92 309.7 0.0 2.6e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER27897.1 - 4.9e-12 46.6 0.5 1.5e-11 45.0 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Nup188 PF10487.4 EER27898.1 - 5e-59 200.1 1.2 1.7e-58 198.4 0.8 1.8 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 EER27899.1 - 2.3e-95 318.4 0.0 4.2e-95 317.6 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EER27899.1 - 2.4e-54 183.8 0.0 9.1e-52 175.4 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EER27899.1 - 3.5e-51 173.4 0.0 6.1e-51 172.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EER27899.1 - 0.00022 20.7 0.0 0.00054 19.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase C26 His_biosynth PF00977.16 EER27899.1 - 0.0027 17.0 0.2 0.013 14.8 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein NanE PF04131.9 EER27899.1 - 0.0051 15.7 0.3 0.019 13.9 0.0 2.0 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase QRPTase_C PF01729.14 EER27899.1 - 0.0075 15.8 0.6 0.15 11.5 0.1 2.6 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.13 EER27899.1 - 3.2 6.4 5.2 0.53 9.0 0.5 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PTCB-BRCT PF12738.2 EER27900.1 - 9e-11 41.4 0.2 1.9e-10 40.4 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EER27900.1 - 1.6e-10 40.9 0.1 2.9e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 EER27900.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.6 1 0 0 1 1 1 0 WGR domain Brix PF04427.13 EER27901.1 - 2e-46 158.0 0.0 2.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain UPF1_Zn_bind PF09416.5 EER27902.1 - 9.5e-72 239.5 4.1 9.5e-72 239.5 2.9 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EER27902.1 - 7.8e-59 198.4 0.0 1.2e-58 197.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EER27902.1 - 3.5e-56 190.4 1.0 5.4e-56 189.8 0.7 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER27902.1 - 2e-13 49.8 0.3 5.3e-13 48.5 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EER27902.1 - 9.9e-12 44.8 0.1 1.8e-10 40.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EER27902.1 - 5.8e-09 36.0 0.0 1.1e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EER27902.1 - 0.001 18.7 0.0 0.0021 17.7 0.0 1.6 1 0 0 1 1 1 1 Helicase PIF1 PF05970.9 EER27902.1 - 0.0056 15.6 0.0 0.79 8.6 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.4 EER27902.1 - 0.0069 15.3 1.5 0.025 13.5 0.1 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Ribosomal_S13_N PF08069.7 EER27902.1 - 0.0098 15.7 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain DEAD PF00270.24 EER27902.1 - 0.014 14.8 0.2 0.032 13.7 0.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase UvrD-helicase PF00580.16 EER27902.1 - 0.033 13.4 0.0 0.21 10.8 0.0 2.2 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EER27902.1 - 0.095 11.9 0.0 0.2 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EER27902.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AhpC-TSA_2 PF13911.1 EER27903.1 - 3.1e-15 56.0 0.0 5.6e-15 55.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EER27903.1 - 4.7e-05 23.0 0.0 6.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EER27903.1 - 0.0021 17.6 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin adh_short_C2 PF13561.1 EER27904.1 - 3.4e-31 108.8 0.2 4.5e-31 108.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER27904.1 - 1.4e-25 90.1 0.9 2.1e-25 89.5 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER27904.1 - 3.6e-08 33.2 0.2 5.6e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EER27904.1 - 0.019 14.4 0.4 0.038 13.4 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family PI-PLC-X PF00388.14 EER27905.1 - 2.2e-59 199.0 0.0 3.9e-59 198.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EER27905.1 - 6.7e-39 132.5 0.0 1.3e-38 131.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EER27905.1 - 1.8e-06 27.8 0.0 4.7e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.25 EER27905.1 - 4.7e-06 26.3 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_1 PF00036.27 EER27905.1 - 0.0018 17.4 1.0 0.0081 15.3 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 EER27905.1 - 0.012 15.7 0.5 0.39 10.9 0.2 2.9 2 1 1 3 3 3 0 EF-hand domain pair GDPD PF03009.12 EER27905.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family EF-hand_6 PF13405.1 EER27905.1 - 0.31 11.0 3.2 0.38 10.7 0.0 2.7 3 0 0 3 3 3 0 EF-hand domain Glyco_hydro_61 PF03443.9 EER27906.1 - 0.1 12.3 0.0 0.88 9.3 0.0 2.3 2 1 1 3 3 3 0 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 EER27906.1 - 0.14 12.4 0.0 0.65 10.2 0.0 1.9 1 1 0 1 1 1 0 Chitin binding domain Sec5 PF15469.1 EER27907.1 - 2e-35 122.1 0.1 3.3e-34 118.2 0.1 2.3 2 0 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EER27907.1 - 1.1e-05 25.2 0.1 4e-05 23.3 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 ISG65-75 PF11727.3 EER27907.1 - 0.5 9.3 3.7 1.4 7.9 0.1 2.5 2 1 0 2 2 2 0 Invariant surface glycoprotein UPF0449 PF15136.1 EER27907.1 - 8.9 6.5 8.4 26 5.1 0.2 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 Iso_dh PF00180.15 EER27908.1 - 7e-100 334.3 0.0 9e-100 333.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Eaf7 PF07904.8 EER27909.1 - 2e-21 75.7 0.0 8.4e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 Chromatin modification-related protein EAF7 Spc97_Spc98 PF04130.8 EER27910.1 - 2.5e-59 201.0 1.4 3.7e-59 200.4 1.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family IL5 PF02025.10 EER27910.1 - 0.0025 17.8 0.2 10 6.1 0.0 3.3 3 0 0 3 3 3 2 Interleukin 5 rRNA_processing PF08524.6 EER27911.1 - 0.16 11.7 27.8 2.9 7.6 19.2 2.0 1 1 0 1 1 1 0 rRNA processing DUF4210 PF13915.1 EER27912.1 - 3.2e-25 88.2 0.1 8e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EER27912.1 - 5.2e-23 80.6 0.4 1.2e-22 79.5 0.2 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis CAP_N PF01213.14 EER27913.1 - 2.5e-83 279.9 1.0 4.2e-83 279.1 0.7 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EER27913.1 - 7.8e-56 187.8 1.1 1.3e-55 187.0 0.8 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EER27913.1 - 0.35 10.2 4.9 0.73 9.2 1.8 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor C PfkB PF00294.19 EER27914.1 - 1.8e-18 66.7 0.0 3.3e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ribonuclease_3 PF00636.21 EER27916.1 - 2.1e-08 34.6 0.0 4.4e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EER27916.1 - 2.9e-07 30.4 0.0 0.0026 17.7 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EER27916.1 - 6.8e-05 23.3 0.0 0.00022 21.7 0.0 1.8 2 0 0 2 2 2 1 Double-stranded RNA binding motif ECH PF00378.15 EER27917.1 - 1.4e-24 86.6 0.0 1.7e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Synapsin_C PF02750.9 EER27917.1 - 0.0056 15.7 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 Synapsin, ATP binding domain BSP PF04450.7 EER27918.1 - 3.2e-67 225.9 0.0 3.7e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EER27918.1 - 7.4e-05 22.8 0.1 0.00011 22.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EER27918.1 - 0.0038 16.9 0.2 0.0069 16.0 0.1 1.5 2 0 0 2 2 2 1 SprT-like family DUF2268 PF10026.4 EER27918.1 - 0.087 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) CLASP_N PF12348.3 EER27919.1 - 6.4e-151 500.0 0.0 1.2e-88 296.2 0.0 2.6 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EER27919.1 - 7.1e-09 35.0 0.2 0.88 9.8 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EER27919.1 - 1.4e-05 25.2 3.3 0.013 15.7 0.2 5.8 6 1 1 7 7 7 2 HEAT repeats HEAT_EZ PF13513.1 EER27919.1 - 0.043 14.3 1.0 29 5.3 0.0 4.8 6 0 0 6 6 6 0 HEAT-like repeat Cnd1 PF12717.2 EER27919.1 - 0.062 13.1 0.0 4.9 6.9 0.0 3.2 2 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Acetyltransf_8 PF13523.1 EER27920.1 - 3.3e-45 153.6 2.7 4.9e-45 153.1 1.8 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EER27920.1 - 0.0041 17.2 0.3 0.0069 16.5 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 EER27921.1 - 6.4e-76 255.3 24.7 2.4e-40 138.6 7.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EER27921.1 - 2.6e-64 215.6 0.0 1e-30 106.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EER27921.1 - 1.4e-16 60.4 2.4 8.1e-06 25.2 0.0 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EER27921.1 - 5.6e-11 41.6 0.1 0.00036 19.2 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EER27921.1 - 7.4e-10 38.2 0.2 0.00033 20.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EER27921.1 - 2.6e-09 37.4 0.1 0.28 11.1 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EER27921.1 - 5.6e-09 36.2 3.8 6.4e-05 23.0 0.2 3.6 3 0 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.12 EER27921.1 - 2.2e-07 30.9 0.0 0.0015 18.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_17 PF13207.1 EER27921.1 - 2.3e-07 31.6 0.0 0.0079 17.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EER27921.1 - 3.2e-07 30.5 0.1 0.17 12.0 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EER27921.1 - 5.3e-06 26.1 0.6 0.71 9.4 0.0 4.0 4 1 1 5 5 5 2 AAA domain AAA_10 PF12846.2 EER27921.1 - 5.7e-06 25.9 0.3 0.013 14.9 0.0 3.3 3 1 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 EER27921.1 - 1.3e-05 24.7 0.0 0.12 11.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EER27921.1 - 8.8e-05 22.3 3.6 0.18 11.7 0.2 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EER27921.1 - 0.00013 21.2 0.0 0.34 10.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EER27921.1 - 0.00016 22.0 0.0 0.23 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EER27921.1 - 0.00035 20.4 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF3987 PF13148.1 EER27921.1 - 0.00068 18.3 0.0 0.49 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) AAA_19 PF13245.1 EER27921.1 - 0.00084 19.0 0.9 0.46 10.2 0.0 3.4 3 0 0 3 3 3 1 Part of AAA domain SRP54 PF00448.17 EER27921.1 - 0.0013 18.2 0.1 0.48 9.8 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 EER27921.1 - 0.002 18.4 0.1 2.8 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EER27921.1 - 0.0023 17.4 0.1 0.066 12.6 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EER27921.1 - 0.0067 16.1 0.3 2.3 7.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EER27921.1 - 0.011 15.4 0.0 10 5.8 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) MTH865 PF07747.6 EER27921.1 - 0.021 14.4 0.0 2.8 7.6 0.0 2.7 2 0 0 2 2 2 0 MTH865-like family Rad17 PF03215.10 EER27921.1 - 0.06 12.0 0.0 2.4 6.7 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ResIII PF04851.10 EER27921.1 - 0.073 12.8 0.0 13 5.6 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATP_bind_1 PF03029.12 EER27921.1 - 0.083 12.4 1.9 9 5.7 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EER27921.1 - 0.13 12.2 0.1 16 5.4 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RhoGAP PF00620.22 EER27922.1 - 1.8e-46 157.5 0.0 6.9e-46 155.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EER27922.1 - 6.2e-14 51.8 19.1 4.1e-09 36.3 2.2 2.4 2 0 0 2 2 2 2 LIM domain CPSase_L_D3 PF02787.14 EER27922.1 - 1.5 8.5 5.3 1.6 8.5 0.3 2.3 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OrfB_Zn_ribbon PF07282.6 EER27922.1 - 2.9 7.6 15.2 0.62 9.7 0.3 3.7 2 1 1 3 3 3 0 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 EER27922.1 - 7.3 6.0 17.3 7.7 5.9 0.1 4.4 3 1 0 3 3 3 0 TFIIB zinc-binding DASH_Ask1 PF08655.5 EER27923.1 - 2.4e-33 113.7 0.2 3.9e-33 113.0 0.2 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 Exo_endo_phos_2 PF14529.1 EER27924.1 - 0.057 13.0 2.0 0.057 13.0 0.1 2.0 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase LicD PF04991.8 EER27925.1 - 2.9e-35 122.2 11.1 1.1e-33 117.0 7.7 2.2 1 1 0 1 1 1 1 LicD family WLM PF08325.5 EER27926.1 - 4.9e-44 150.4 0.0 9.5e-44 149.4 0.0 1.4 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EER27926.1 - 2.1e-05 24.4 1.7 6.1e-05 22.8 0.5 2.0 2 1 0 2 2 2 1 Protein of unknown function DUF45 PB1 PF00564.19 EER27926.1 - 0.00038 20.0 0.0 0.0011 18.6 0.0 1.7 1 0 0 1 1 1 1 PB1 domain SprT-like PF10263.4 EER27926.1 - 0.00074 19.2 0.2 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 SprT-like family ubiquitin PF00240.18 EER27926.1 - 0.0081 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_MA_2 PF13485.1 EER27926.1 - 0.079 13.0 0.1 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Thiolase_N PF00108.18 EER27927.1 - 9.4e-72 241.1 0.1 1.6e-71 240.3 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EER27927.1 - 1.2e-42 144.1 0.3 2.7e-42 143.0 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EER27927.1 - 0.059 12.8 0.8 0.62 9.4 0.7 2.3 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain TH1 PF04858.8 EER27927.1 - 0.17 9.9 0.0 0.27 9.3 0.0 1.2 1 0 0 1 1 1 0 TH1 protein HSP70 PF00012.15 EER27928.1 - 9.1e-163 542.3 5.2 9.1e-163 542.3 3.6 2.7 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EER27928.1 - 1.5e-10 40.1 0.0 5.1e-10 38.4 0.0 1.7 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EER27928.1 - 0.00011 22.0 0.1 1.1 9.0 0.0 3.3 2 1 0 2 2 2 2 Cell division protein FtsA Chitin_synth_2 PF03142.10 EER27929.1 - 1.3e-23 83.2 3.7 1.8e-22 79.4 2.2 2.5 2 1 0 2 2 2 1 Chitin synthase Glyco_tranf_2_3 PF13641.1 EER27929.1 - 1.5e-16 60.8 0.0 2.9e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EER27929.1 - 1.1e-15 57.9 9.4 1.1e-15 57.9 6.5 3.0 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EER27929.1 - 0.041 13.5 0.1 7.6 6.1 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferase family 2 La PF05383.12 EER27930.1 - 1.2e-17 63.4 0.1 2e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EER27930.1 - 5.3e-07 29.5 0.1 3e-06 27.1 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER27930.1 - 6e-07 29.0 0.1 1.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER27930.1 - 0.00099 18.9 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DAO PF01266.19 EER27931.1 - 2.9e-52 177.7 0.1 3.4e-52 177.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EER27931.1 - 5e-07 29.9 0.0 0.0084 16.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER27931.1 - 0.00087 19.0 0.1 0.3 10.8 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EER27931.1 - 0.0076 15.2 0.1 0.026 13.4 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EER27931.1 - 0.0083 16.1 0.2 0.0083 16.1 0.2 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EER27931.1 - 0.023 13.6 0.2 0.05 12.5 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EER27931.1 - 0.028 12.8 0.6 0.43 8.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein PALP PF00291.20 EER27931.1 - 0.04 13.1 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Thi4 PF01946.12 EER27931.1 - 0.043 12.8 0.1 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EER27931.1 - 0.065 13.1 0.8 0.92 9.3 0.2 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EER27931.1 - 3.4 6.4 11.2 0.32 9.7 0.4 2.4 3 0 0 3 3 2 0 FAD binding domain MFS_1 PF07690.11 EER27932.1 - 1.9e-32 112.3 26.2 1.9e-32 112.3 18.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PTR2 PF00854.16 EER27932.1 - 0.0013 17.5 2.8 0.0013 17.5 1.9 1.9 3 0 0 3 3 3 1 POT family Cu_amine_oxid PF01179.15 EER27933.1 - 2.3e-162 540.4 0.0 2.8e-162 540.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EER27933.1 - 1.8e-07 31.1 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EER27933.1 - 3.6e-05 23.7 0.0 6.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Rad51 PF08423.6 EER27934.1 - 4.2e-22 78.2 0.0 6.8e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EER27934.1 - 2.5e-13 49.8 0.0 4.2e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EER27934.1 - 1.6e-06 27.3 0.1 8.5e-06 25.0 0.0 1.9 1 1 0 1 1 1 1 KaiC RecA PF00154.16 EER27934.1 - 0.0039 16.3 0.3 0.016 14.3 0.2 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.1 EER27934.1 - 0.023 14.8 0.2 0.11 12.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain FA_desaturase PF00487.19 EER27935.1 - 1.1e-26 93.8 13.9 1.9e-26 93.0 9.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EER27935.1 - 3.7e-06 27.0 0.0 8.9e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3474) TRAPPC10 PF12584.3 EER27936.1 - 2.9e-37 127.3 0.0 1.4e-36 125.2 0.0 2.0 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EER27936.1 - 0.001 18.6 0.1 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 Apc3 PF12895.2 EER27936.1 - 0.063 13.4 0.7 0.17 12.0 0.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Ank_2 PF12796.2 EER27937.1 - 1.4e-12 47.8 0.1 2.8e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EER27937.1 - 1.4e-12 46.7 4.9 3e-07 29.8 0.7 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EER27937.1 - 9.1e-12 44.8 0.2 5.2e-11 42.3 0.2 2.4 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.1 EER27937.1 - 6.5e-09 35.1 0.7 0.00029 20.7 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EER27937.1 - 1.8e-08 34.6 0.2 5.5e-08 33.1 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER27937.1 - 2.1e-07 30.9 1.8 1.5e-05 25.0 0.5 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Trypsin PF00089.21 EER27938.1 - 1.9e-06 27.6 0.4 6.2e-06 25.9 0.3 1.7 1 1 0 1 1 1 1 Trypsin SUI1 PF01253.17 EER27939.1 - 8.3e-18 63.9 0.3 1.8e-17 62.9 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Velvet PF11754.3 EER27940.1 - 2e-63 213.6 0.0 2.8e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Velvet factor Tropomyosin_1 PF12718.2 EER27941.1 - 0.031 14.1 0.5 0.031 14.1 0.4 2.1 2 0 0 2 2 2 0 Tropomyosin like Striatin PF08232.7 EER27941.1 - 1.8 8.8 8.4 0.49 10.7 2.6 2.3 1 1 1 2 2 2 0 Striatin family MFS_1 PF07690.11 EER27942.1 - 1.1e-34 119.7 20.9 1.1e-34 119.7 14.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TMF_TATA_bd PF12325.3 EER27942.1 - 0.089 12.5 0.2 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Abhydrolase_3 PF07859.8 EER27943.1 - 7.7e-65 218.3 0.1 1e-64 218.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EER27943.1 - 2e-07 30.4 0.1 6.6e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EER27943.1 - 2.7e-06 26.3 0.2 1.9e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DUF2424 PF10340.4 EER27943.1 - 3.1e-05 22.7 0.0 7.5e-05 21.5 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EER27943.1 - 0.00017 21.3 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EER27943.1 - 0.03 13.7 0.0 0.059 12.7 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.4 EER27943.1 - 0.1 11.8 0.1 0.39 9.9 0.1 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase DHDPS PF00701.17 EER27944.1 - 2.1e-39 134.8 0.0 3.9e-39 133.9 0.0 1.4 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 EER27944.1 - 8.6e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase AP_endonuc_2 PF01261.19 EER27944.1 - 0.0062 15.8 0.0 0.015 14.6 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel DUF2070 PF09843.4 EER27944.1 - 0.036 13.5 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribonuc_L-PSP PF01042.16 EER27945.1 - 5.8e-29 100.3 0.0 6.8e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sec7_N PF12783.2 EER27945.1 - 0.092 12.1 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal D-ser_dehydrat PF14031.1 EER27946.1 - 8.5e-26 89.9 0.0 1.5e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EER27946.1 - 2.4e-13 50.1 0.0 5.2e-13 49.0 0.0 1.6 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EER27947.1 - 1.1e-35 122.9 2.1 4.1e-35 121.0 1.5 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EER27947.1 - 1.6e-15 56.3 0.0 3.7e-15 55.1 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EER27947.1 - 5.4e-14 52.5 0.1 2.3e-13 50.5 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EER27947.1 - 2.7e-06 27.9 0.0 5.9e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 EER27947.1 - 0.00014 21.3 0.0 0.0004 19.8 0.0 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1540 PF07561.6 EER27947.1 - 0.051 13.6 0.5 0.11 12.5 0.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1540) PEP_mutase PF13714.1 EER27948.1 - 3.4e-64 216.3 0.0 3.9e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Cyclase PF04199.8 EER27949.1 - 4.6e-12 45.9 1.1 9.3e-12 44.9 0.8 1.6 1 1 0 1 1 1 1 Putative cyclase AA_permease_2 PF13520.1 EER27950.1 - 1.8e-60 204.6 49.5 2.2e-60 204.4 34.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER27950.1 - 8.6e-33 113.3 44.6 1.1e-32 112.9 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M20 PF01546.23 EER27951.1 - 1.4e-15 57.2 0.0 2e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EER27951.1 - 1.7e-14 53.5 0.1 3.3e-14 52.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain UME PF08064.8 EER27951.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 UME (NUC010) domain UQ_con PF00179.21 EER27952.1 - 9.2e-22 76.9 0.0 1.5e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EER27952.1 - 0.0081 15.8 0.0 0.027 14.1 0.0 1.9 1 0 0 1 1 1 1 UEV domain BNIP3 PF06553.7 EER27952.1 - 0.068 12.5 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 BNIP3 HCV_NS5a PF01506.14 EER27952.1 - 0.41 10.3 2.9 0.85 9.3 2.0 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a protein membrane anchor JmjC PF02373.17 EER27953.1 - 1.5e-36 125.1 1.7 7.6e-36 122.8 0.5 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EER27953.1 - 9e-19 67.5 4.0 1.7e-18 66.5 2.7 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EER27953.1 - 1.5e-18 66.7 5.5 3.3e-18 65.6 3.8 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EER27953.1 - 1.4e-14 53.3 0.5 3.7e-14 51.9 0.4 1.8 1 0 0 1 1 1 1 jmjN domain CusF_Ec PF11604.3 EER27953.1 - 0.031 14.1 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 Copper binding periplasmic protein CusF Carn_acyltransf PF00755.15 EER27954.1 - 1.5e-167 558.2 0.0 4.2e-150 500.6 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase CAP PF00188.21 EER27955.1 - 1.3e-17 64.4 4.3 1.8e-17 63.9 3.0 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mfp-3 PF04202.8 EER27955.1 - 0.94 9.7 6.8 0.41 10.8 0.2 2.4 2 0 0 2 2 2 0 Foot protein 3 PAT1 PF09770.4 EER27955.1 - 8.7 4.4 13.0 9.8 4.2 9.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Thioredox_DsbH PF03190.10 EER27956.1 - 1e-68 230.1 0.0 2.1e-68 229.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EER27956.1 - 5e-07 29.6 0.0 1.6e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Glyco_hydro_88 PF07470.8 EER27956.1 - 0.023 13.7 0.0 24 3.8 0.1 3.6 4 0 0 4 4 4 0 Glycosyl Hydrolase Family 88 Glyco_hydro_9 PF00759.14 EER27956.1 - 0.04 12.8 0.2 0.068 12.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Glyco_hydro_76 PF03663.9 EER27956.1 - 0.046 13.1 0.0 1.3 8.2 0.0 2.6 3 0 0 3 3 3 0 Glycosyl hydrolase family 76 Thioredoxin_2 PF13098.1 EER27956.1 - 0.14 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain WD40 PF00400.27 EER27957.1 - 6.3e-26 89.2 17.3 3.3e-08 33.0 0.5 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EER27957.1 - 0.018 13.2 0.9 1 7.4 0.1 2.9 2 1 0 3 3 3 0 Nucleoporin Nup120/160 LSM14 PF12701.2 EER27958.1 - 2.9e-33 113.5 0.0 6.4e-33 112.4 0.0 1.6 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EER27958.1 - 3e-19 69.4 4.1 3e-19 69.4 2.8 1.8 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 EER27958.1 - 0.0033 17.3 0.0 0.007 16.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain GRP PF07172.6 EER27958.1 - 3.2 8.2 29.6 6.3 7.3 0.4 2.8 2 0 0 2 2 2 0 Glycine rich protein family ACBP PF00887.14 EER27959.1 - 2.8e-29 100.6 0.1 3.2e-28 97.2 0.0 2.2 2 0 0 2 2 2 1 Acyl CoA binding protein SPT6_acidic PF14632.1 EER27959.1 - 0.0077 16.3 16.3 0.016 15.3 11.3 1.6 1 0 0 1 1 1 1 Acidic N-terminal SPT6 NSP2-B_epitope PF14757.1 EER27959.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Atg14 PF10186.4 EER27959.1 - 0.11 11.4 2.6 2 7.2 0.0 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CDC45 PF02724.9 EER27959.1 - 1.6 6.6 13.2 2.2 6.1 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.3 EER27959.1 - 6.8 7.3 22.0 1.7 9.3 12.4 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CHCH PF06747.8 EER27960.1 - 2.7e-08 33.5 2.8 2.7e-08 33.5 1.9 2.6 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 EER27960.1 - 0.016 15.2 6.7 0.44 10.6 1.0 2.7 2 1 1 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EER27960.1 - 0.3 10.8 12.0 1.5 8.6 1.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EER27960.1 - 1.3 9.1 10.6 2.7 8.0 1.2 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb POP1 PF06978.6 EER27961.1 - 0.06 12.9 0.6 0.12 12.0 0.4 1.5 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Prefoldin PF02996.12 EER27962.1 - 6.8e-25 87.0 1.7 8.8e-25 86.6 1.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EER27962.1 - 0.0038 16.9 2.4 0.28 10.9 0.3 2.2 2 0 0 2 2 2 2 Prefoldin subunit Prefoldin_3 PF13758.1 EER27962.1 - 0.016 14.9 0.5 0.034 13.9 0.4 1.6 1 1 0 1 1 1 0 Prefoldin subunit Mating_N PF12731.2 EER27962.1 - 0.082 12.7 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Mating-type protein beta 1 Sec2p PF06428.6 EER27962.1 - 0.11 12.3 3.0 3.1 7.6 0.3 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p BRE1 PF08647.6 EER27962.1 - 0.18 11.7 1.9 5.7 6.9 0.1 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase tRNA-synt_2b PF00587.20 EER27963.1 - 4.8e-30 104.3 0.0 7.6e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EER27963.1 - 1.7e-08 34.2 0.1 6.6e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EER27963.1 - 0.013 14.2 0.4 0.043 12.5 0.3 1.8 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) CBF PF03914.12 EER27964.1 - 2.6e-47 160.3 0.1 8.8e-47 158.5 0.1 2.0 1 0 0 1 1 1 1 CBF/Mak21 family DUF2533 PF10752.4 EER27964.1 - 0.013 15.7 0.0 0.04 14.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) LANC_like PF05147.8 EER27965.1 - 1.8e-28 99.1 0.2 5.5e-28 97.5 0.1 1.7 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein TPR_12 PF13424.1 EER27966.1 - 0.0026 17.6 2.1 0.013 15.3 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EER27966.1 - 0.013 15.3 0.0 0.1 12.5 0.0 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EER27966.1 - 0.014 15.1 0.0 0.42 10.5 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc5 PF12862.2 EER27966.1 - 0.015 15.1 0.1 0.06 13.1 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 TPR_11 PF13414.1 EER27966.1 - 0.035 13.7 1.6 0.23 11.1 0.0 2.9 3 0 0 3 3 3 0 TPR repeat TPR_4 PF07721.9 EER27966.1 - 0.064 13.7 0.1 0.22 12.0 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EER27966.1 - 0.079 12.5 0.3 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Aa_trans PF01490.13 EER27967.1 - 1.4e-23 83.0 33.0 5.9e-23 81.0 22.9 1.9 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein GCV_T PF01571.16 EER27968.1 - 2.9e-56 190.1 0.0 3.9e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EER27968.1 - 3.4e-17 62.2 0.0 6.5e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain APS_kinase PF01583.15 EER27969.1 - 2.5e-69 231.8 0.0 3.3e-69 231.5 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EER27969.1 - 2.4e-06 27.4 0.0 3.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EER27969.1 - 0.00031 21.5 0.0 0.00048 20.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EER27969.1 - 0.00043 20.5 0.0 0.001 19.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EER27969.1 - 0.0014 17.8 0.0 0.0026 16.9 0.0 1.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EER27969.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain V-ATPase_C PF03223.10 EER27970.1 - 4.8e-114 381.1 0.0 5.4e-114 380.9 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C 4HBT PF03061.17 EER27971.1 - 2.9e-11 43.3 0.0 5.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Ligase_CoA PF00549.14 EER27972.1 - 5.8e-35 120.1 1.7 6e-18 64.9 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EER27972.1 - 4.6e-13 49.4 1.8 3.9e-12 46.5 0.3 3.1 4 0 0 4 4 4 1 CoA binding domain Succ_CoA_lig PF13607.1 EER27972.1 - 2.7e-09 36.7 0.1 1.2e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EER27972.1 - 0.002 18.2 0.5 0.0071 16.5 0.2 2.0 2 0 0 2 2 2 1 CoA binding domain Hid1 PF12722.2 EER27973.1 - 9.7 3.7 10.9 11 3.4 7.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rad60-SLD PF11976.3 EER27974.1 - 9.2e-21 73.3 0.3 1.1e-20 73.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EER27974.1 - 2.1e-07 30.2 0.1 2.5e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Nup84_Nup100 PF04121.8 EER27975.1 - 1.1e-60 205.1 3.9 6e-48 163.0 0.5 3.2 2 1 0 2 2 2 2 Nuclear pore protein 84 / 107 Daxx PF03344.10 EER27975.1 - 2.1 6.7 27.4 3.4 6.0 19.0 1.2 1 0 0 1 1 1 0 Daxx Family E1-E2_ATPase PF00122.15 EER27976.1 - 1.4e-59 200.9 1.0 2.9e-59 199.9 0.7 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EER27976.1 - 3.9e-46 156.8 6.7 3.9e-46 156.8 4.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EER27976.1 - 3.1e-28 99.6 0.0 1.3e-27 97.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER27976.1 - 4.5e-20 71.3 0.0 1e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EER27976.1 - 1.9e-15 57.5 0.0 7.2e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EER27976.1 - 8.4e-06 25.5 0.9 7e-05 22.5 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EER27976.1 - 2.4e-05 23.7 0.1 9.3e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2236 PF09995.4 EER27977.1 - 1.1e-10 41.2 0.1 3.3e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) NTase_sub_bind PF08780.6 EER27977.1 - 0.035 13.8 0.0 0.074 12.8 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase substrate binding protein like Aldedh PF00171.17 EER27978.1 - 1.2e-107 360.1 0.1 1.5e-107 359.7 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tubulin PF00091.20 EER27979.1 - 1.2e-69 234.4 0.0 1.9e-69 233.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EER27979.1 - 2.4e-48 163.3 0.1 3.9e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EER27979.1 - 2.8e-05 24.1 0.0 7.1e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EER27979.1 - 0.0065 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 EER27980.1 - 9.1e-16 57.2 0.1 2.5e-07 30.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER27980.1 - 6.5e-15 54.8 0.2 3.7e-06 26.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER27980.1 - 4.4e-11 42.4 0.1 4.3e-08 32.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EER27980.1 - 0.053 13.3 0.0 0.053 13.3 0.0 3.0 3 1 1 4 4 4 0 RNA binding motif S-antigen PF05756.6 EER27980.1 - 1.1 9.3 4.9 0.3 11.0 0.7 2.1 2 0 0 2 2 2 0 S-antigen protein Ammonium_transp PF00909.16 EER27981.1 - 7e-98 327.6 22.0 1.7e-50 171.6 2.0 2.0 1 1 1 2 2 2 2 Ammonium Transporter Family Corona_NS2 PF04753.7 EER27981.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 DUF1691 PF07950.6 EER27981.1 - 0.54 10.2 3.9 1.4 8.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Pkinase PF00069.20 EER27982.1 - 1.8e-64 217.3 0.0 2.8e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27982.1 - 1e-33 116.4 0.0 3.3e-33 114.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER27982.1 - 3e-07 29.7 0.0 1.8e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EER27982.1 - 4.9e-05 23.1 0.0 0.0029 17.3 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EER27982.1 - 0.005 15.7 0.1 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EER27982.1 - 0.023 14.0 0.2 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Vac_ImportDeg PF09783.4 EER27983.1 - 4.8e-69 231.3 2.3 6e-69 231.0 1.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein TOH_N PF12549.3 EER27983.1 - 2.7 7.6 5.5 3 7.5 0.6 3.0 3 0 0 3 3 3 0 Tyrosine hydroxylase N terminal Mago_nashi PF02792.9 EER27984.1 - 6.1e-73 243.2 0.3 7.4e-73 242.9 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 EER27985.1 - 1.4e-93 314.0 8.7 2.6e-93 313.1 6.0 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EER27985.1 - 7.2e-61 203.6 0.0 2.2e-60 202.0 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EER27985.1 - 1e-60 203.4 0.5 2.4e-60 202.2 0.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EER27985.1 - 2.9e-13 49.9 5.3 1.8e-06 28.1 0.0 4.9 1 1 3 4 4 4 4 HEAT repeats HEAT PF02985.17 EER27985.1 - 0.0004 20.2 0.3 1.7 8.9 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EER27985.1 - 0.0011 19.3 2.9 0.18 12.3 0.0 4.9 3 1 1 4 4 4 2 HEAT-like repeat Cnd1 PF12717.2 EER27985.1 - 0.0023 17.7 9.2 0.23 11.2 0.0 4.1 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DAGK_cat PF00781.19 EER27986.1 - 5e-25 87.4 0.0 8.6e-25 86.6 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 EER27987.1 - 4.7e-45 153.6 1.1 3e-35 121.6 0.9 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 TAN PF11640.3 EER27987.1 - 0.023 14.4 1.1 0.062 13.0 0.1 2.1 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair ubiquitin PF00240.18 EER27988.1 - 0.00061 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family TPR_4 PF07721.9 EER27988.1 - 0.034 14.5 0.4 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2407 PF10302.4 EER27988.1 - 0.055 13.6 0.3 0.23 11.6 0.0 2.0 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EER27988.1 - 0.1 12.2 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF4050 PF13259.1 EER27988.1 - 0.47 10.3 3.3 0.3 11.0 1.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4050) DUF1604 PF07713.8 EER27989.1 - 5.5e-39 131.8 3.8 2e-38 130.0 0.6 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EER27989.1 - 2.4e-07 30.4 1.4 3.7e-07 29.8 0.3 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EER27989.1 - 0.00068 19.4 0.1 0.0029 17.4 0.1 2.2 1 0 0 1 1 1 1 DExH-box splicing factor binding site Pkinase PF00069.20 EER27990.1 - 4e-74 249.0 0.2 5.9e-73 245.2 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER27990.1 - 4.3e-39 134.1 0.1 1.5e-38 132.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EER27990.1 - 1.3e-17 62.9 0.3 2.3e-17 62.1 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EER27990.1 - 7.5e-06 25.1 0.0 6.2e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EER27990.1 - 4.4e-05 22.6 0.1 8.1e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 EER27990.1 - 0.0021 17.3 0.1 0.0037 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 EER27990.1 - 0.005 16.6 0.0 0.06 13.0 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EER27990.1 - 0.016 14.5 0.0 0.041 13.2 0.0 1.7 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 EER27990.1 - 0.018 14.4 0.1 0.042 13.2 0.1 1.6 1 0 0 1 1 1 0 RIO1 family SET PF00856.23 EER27991.1 - 6.6e-23 81.7 0.0 1.7e-22 80.4 0.0 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EER27991.1 - 2.5e-12 46.9 7.2 2.5e-12 46.9 5.0 2.2 3 0 0 3 3 3 1 Pre-SET motif APH PF01636.18 EER27992.1 - 1e-10 41.7 0.0 1.9e-09 37.6 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EER27992.1 - 0.0016 17.6 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EER27994.1 - 2.6e-15 56.8 0.0 2.5e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER27994.1 - 9.6e-10 38.3 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EER27994.1 - 0.041 12.5 0.0 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Ion_trans PF00520.26 EER27996.1 - 1.9e-107 356.9 78.6 7.1e-36 123.3 2.2 5.0 5 1 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 EER27996.1 - 0.0018 17.4 0.0 0.0059 15.8 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EER27996.1 - 0.027 14.5 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_6 PF13405.1 EER27996.1 - 0.037 13.9 0.0 0.24 11.3 0.0 2.4 1 0 0 1 1 1 0 EF-hand domain Proteasom_Rpn13 PF04683.8 EER27997.1 - 3.6e-28 97.4 0.0 5.6e-28 96.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ribosomal_L6e PF01159.14 EER27998.1 - 2.9e-38 130.4 0.1 4.3e-38 129.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e FA_hydroxylase PF04116.8 EER27999.1 - 4.4e-11 43.1 7.8 4.4e-11 43.1 5.4 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 EER28001.1 - 8.3e-21 74.6 0.0 1.1e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER28001.1 - 3.7e-09 36.5 0.2 1e-08 35.0 0.1 1.7 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EER28001.1 - 0.00062 19.8 0.2 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EER28001.1 - 0.00079 19.4 0.1 0.0023 17.9 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EER28001.1 - 0.0023 17.4 0.0 0.0036 16.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EER28001.1 - 0.0042 16.1 0.1 0.0083 15.1 0.0 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EER28001.1 - 0.0049 17.2 0.1 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EER28001.1 - 0.0053 16.4 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EER28001.1 - 0.0061 15.6 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 EER28001.1 - 0.0082 16.3 0.1 0.016 15.4 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding adh_short_C2 PF13561.1 EER28001.1 - 0.014 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.10 EER28001.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 EER28001.1 - 0.084 11.7 0.2 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Minor_capsid_3 PF12691.2 EER28001.1 - 0.095 12.3 0.1 0.85 9.3 0.0 2.1 2 0 0 2 2 2 0 Minor capsid protein from bacteriophage Eno-Rase_NADH_b PF12242.3 EER28001.1 - 0.14 12.0 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sas10 PF09368.5 EER28002.1 - 4.7e-29 100.3 5.1 4.7e-29 100.3 3.5 3.0 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EER28002.1 - 3.3e-15 56.0 0.7 3.2e-14 52.8 0.1 2.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family MutS_V PF00488.16 EER28003.1 - 7.2e-47 159.7 0.2 1.8e-44 151.9 0.0 3.2 2 1 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EER28003.1 - 1.6e-20 73.8 0.1 3.6e-20 72.6 0.0 1.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EER28003.1 - 0.0043 17.1 0.0 0.013 15.6 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA PF00004.24 EER28003.1 - 0.064 13.4 0.2 0.92 9.7 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EER28004.1 - 5.4e-47 159.8 0.0 4.7e-45 153.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EER28004.1 - 3.5e-25 87.7 0.1 1.2e-24 86.0 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EER28004.1 - 5.1e-19 68.7 0.1 1.5e-09 38.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER28004.1 - 2e-13 50.7 3.2 9.9e-05 22.4 0.0 5.1 3 2 2 5 5 5 3 AAA ATPase domain AAA_5 PF07728.9 EER28004.1 - 6e-13 48.7 2.5 3.8e-08 33.1 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EER28004.1 - 1.6e-10 41.2 0.2 0.00067 19.7 0.0 3.4 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EER28004.1 - 8.1e-07 28.6 0.6 0.00039 19.9 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EER28004.1 - 6.3e-06 26.1 0.2 0.076 12.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain Arch_ATPase PF01637.13 EER28004.1 - 7.8e-06 25.7 2.7 0.15 11.7 0.0 4.3 3 2 0 3 3 3 1 Archaeal ATPase NACHT PF05729.7 EER28004.1 - 1.4e-05 24.8 0.0 0.19 11.3 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EER28004.1 - 1.5e-05 25.7 3.1 0.11 13.3 0.0 3.9 4 1 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 EER28004.1 - 4.1e-05 23.0 0.0 0.12 11.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein MobB PF03205.9 EER28004.1 - 6.6e-05 22.6 0.0 0.046 13.4 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EER28004.1 - 6.7e-05 22.9 0.1 0.079 12.9 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EER28004.1 - 7.6e-05 23.0 2.4 0.4 10.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EER28004.1 - 0.00012 21.7 0.0 0.007 16.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain SRP54 PF00448.17 EER28004.1 - 0.0003 20.2 0.1 0.05 13.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EER28004.1 - 0.00045 20.1 0.1 2.2 8.0 0.0 3.2 2 1 1 3 3 2 2 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 EER28004.1 - 0.00059 18.5 0.1 0.076 11.6 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 EER28004.1 - 0.0015 18.6 0.0 0.68 10.1 0.0 2.8 2 1 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 EER28004.1 - 0.0017 17.9 0.6 0.17 11.4 0.0 3.5 3 1 0 4 4 3 1 AAA domain AAA_25 PF13481.1 EER28004.1 - 0.0018 17.6 0.4 0.23 10.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EER28004.1 - 0.0051 16.6 0.0 4.4 7.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EER28004.1 - 0.0081 15.3 0.2 2.2 7.3 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 EER28004.1 - 0.013 15.0 0.0 0.68 9.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EER28004.1 - 0.014 14.5 0.0 0.44 9.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 EER28004.1 - 0.014 15.0 0.0 0.58 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EER28004.1 - 0.016 14.6 0.1 0.25 10.7 0.0 2.9 2 2 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 EER28004.1 - 0.021 14.3 0.1 0.37 10.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UvrD-helicase PF00580.16 EER28004.1 - 0.034 13.4 2.9 0.22 10.7 0.0 2.6 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain UPF0079 PF02367.12 EER28004.1 - 0.035 13.7 0.0 9.1 5.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC_tran PF00005.22 EER28004.1 - 0.041 14.1 1.8 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 ABC transporter DUF258 PF03193.11 EER28004.1 - 0.045 12.9 0.0 6.1 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EER28004.1 - 0.054 13.9 0.0 3 8.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF4446 PF14584.1 EER28004.1 - 0.14 11.9 0.8 0.33 10.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Nucleo_LEF-12 PF06256.6 EER28004.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein Rootletin PF15035.1 EER28004.1 - 0.52 10.2 11.6 1.2 9.1 8.0 1.5 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion V_ATPase_I PF01496.14 EER28004.1 - 1.3 6.8 3.7 1.8 6.3 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EF1_GNE PF00736.14 EER28005.1 - 1.2e-31 108.2 3.2 1.9e-31 107.5 2.2 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EER28005.1 - 2.6e-13 49.8 4.0 8e-13 48.2 2.8 1.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EER28005.1 - 8e-05 23.0 0.0 0.00018 21.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EER28005.1 - 0.0014 18.6 0.4 0.0042 17.0 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain YL1 PF05764.8 EER28005.1 - 0.019 14.5 0.5 0.019 14.5 0.4 1.8 2 0 0 2 2 2 0 YL1 nuclear protein GST_C_2 PF13410.1 EER28005.1 - 0.13 12.2 0.4 1 9.3 0.3 2.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MMgT PF10270.4 EER28006.1 - 1.1e-23 83.7 0.0 1.2e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter UQ_con PF00179.21 EER28008.1 - 7e-34 116.2 0.0 1.3e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER28008.1 - 0.00084 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B Syntaxin PF00804.20 EER28008.1 - 0.11 12.7 0.5 0.23 11.6 0.3 1.5 1 0 0 1 1 1 0 Syntaxin RNB PF00773.14 EER28009.1 - 3.3e-80 269.7 0.1 9e-80 268.3 0.0 1.8 2 0 0 2 2 2 1 RNB domain GLE1 PF07817.8 EER28010.1 - 3.8e-18 65.3 0.0 3.8e-18 65.3 0.0 3.3 3 1 0 3 3 3 1 GLE1-like protein MIP-T3 PF10243.4 EER28010.1 - 2.1 6.7 53.5 2.8 6.2 37.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rossmann-like PF10727.4 EER28011.1 - 0.2 11.3 2.4 0.43 10.3 0.4 2.3 2 0 0 2 2 2 0 Rossmann-like domain Glyco_hydro_17 PF00332.13 EER28012.1 - 2.9e-27 95.5 0.7 2.3e-26 92.5 0.5 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 EMP24_GP25L PF01105.19 EER28013.1 - 1.9e-45 154.7 0.2 2.3e-45 154.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3237 PF11578.3 EER28014.1 - 1.4e-33 115.2 0.0 1.7e-33 115.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Metallophos PF00149.23 EER28015.1 - 1.2e-05 24.8 0.5 2.4e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 14-3-3 PF00244.15 EER28016.1 - 1.3e-10 40.7 0.5 2.9e-10 39.6 0.0 1.6 2 0 0 2 2 2 1 14-3-3 protein Acyl-CoA_dh_1 PF00441.19 EER28017.1 - 1.2e-30 106.6 0.3 1.9e-30 105.9 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EER28017.1 - 6.4e-21 73.6 1.8 1.2e-20 72.7 1.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EER28017.1 - 1.8e-12 47.8 0.1 1.3e-11 45.1 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EER28017.1 - 9.2e-06 25.9 0.1 1.5e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Fungal_trans PF04082.13 EER28018.1 - 3.1e-17 62.3 0.0 5.8e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28018.1 - 1e-15 57.3 26.8 7.2e-08 32.2 7.7 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain HpcH_HpaI PF03328.9 EER28019.1 - 1.8e-39 134.8 0.0 2.1e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EER28019.1 - 0.081 12.1 0.4 14 4.8 0.0 2.8 2 1 0 3 3 3 0 Phosphoenolpyruvate phosphomutase CHORD PF04968.7 EER28020.1 - 4.9e-52 174.0 17.9 2e-27 95.1 3.1 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EER28020.1 - 2.1e-14 53.7 0.1 3.4e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 CS domain Choline_kinase PF01633.15 EER28021.1 - 5.8e-47 159.9 0.0 4.1e-46 157.2 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EER28021.1 - 1.9e-11 44.1 0.1 1.9e-11 44.1 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EER28021.1 - 0.0059 15.7 0.0 0.31 10.1 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase Sod_Cu PF00080.15 EER28022.1 - 9.3e-15 55.0 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3405 PF11885.3 EER28023.1 - 6.5e-218 723.9 0.1 7.7e-218 723.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Arf PF00025.16 EER28025.1 - 4.6e-79 263.7 0.2 5.5e-79 263.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EER28025.1 - 2.9e-15 55.9 0.0 3.6e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EER28025.1 - 2.7e-13 49.6 0.0 3.1e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EER28025.1 - 7.4e-13 47.9 1.5 1.1e-09 37.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EER28025.1 - 6e-11 41.9 0.0 6.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EER28025.1 - 2.2e-08 34.5 0.0 3.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EER28025.1 - 3.7e-06 26.8 0.0 5.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER28025.1 - 0.0045 16.4 0.1 0.037 13.4 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EER28025.1 - 0.0079 15.2 0.3 0.012 14.6 0.2 1.5 1 1 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EER28025.1 - 0.043 13.7 0.2 0.12 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain CorA PF01544.13 EER28026.1 - 8.2e-07 28.3 0.8 0.0081 15.2 0.1 2.5 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Acetyltransf_1 PF00583.19 EER28027.1 - 2.6e-09 36.9 0.0 5.5e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EER28027.1 - 1.3e-05 24.8 0.0 4.4e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EER28027.1 - 5.5e-05 23.2 0.0 8.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER28027.1 - 0.00018 21.6 0.0 0.0039 17.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ribosomal_L1 PF00687.16 EER28028.1 - 2.3e-53 180.7 0.5 2.7e-53 180.5 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family UBA_4 PF14555.1 EER28029.1 - 0.079 12.4 0.0 4.7 6.8 0.0 2.6 2 1 0 2 2 2 0 UBA-like domain DUF364 PF04016.7 EER28029.1 - 0.1 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF364) WH2 PF02205.15 EER28030.1 - 1.9e-09 36.7 0.7 5.4e-09 35.3 0.5 1.8 1 0 0 1 1 1 1 WH2 motif LSM PF01423.17 EER28031.1 - 4.1e-17 61.4 0.0 5.8e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 LSM domain SURF4 PF02077.10 EER28033.1 - 6.8e-97 324.0 6.7 7.7e-97 323.8 4.7 1.0 1 0 0 1 1 1 1 SURF4 family Colicin_V PF02674.11 EER28033.1 - 0.19 11.6 18.1 0.21 11.4 5.0 2.3 2 0 0 2 2 2 0 Colicin V production protein O-antigen_lig PF13425.1 EER28033.1 - 1.8 8.5 16.1 0.27 11.1 5.7 2.6 3 0 0 3 3 3 0 O-antigen ligase like membrane protein DoxX PF07681.7 EER28033.1 - 1.9 8.9 20.1 0.58 10.6 0.5 3.3 3 2 0 3 3 3 0 DoxX HR_lesion PF05514.6 EER28033.1 - 2.6 7.8 14.6 0.13 12.1 0.8 3.8 3 1 1 4 4 4 0 HR-like lesion-inducing IU_nuc_hydro PF01156.14 EER28035.1 - 1.1e-57 195.6 0.0 5.8e-56 189.9 0.0 2.1 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase HLH PF00010.21 EER28036.1 - 2.5e-15 55.8 1.0 5.8e-15 54.7 0.7 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4611 PF15387.1 EER28037.1 - 0.0057 16.7 3.8 0.012 15.7 2.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4611) CDC45 PF02724.9 EER28037.1 - 0.073 11.1 2.1 0.092 10.7 1.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EER28037.1 - 0.81 9.1 4.2 1.2 8.6 2.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EER28037.1 - 1.3 8.1 5.4 2 7.5 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 EER28037.1 - 3.7 7.0 7.3 6.5 6.3 5.1 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Med3 PF11593.3 EER28037.1 - 7.2 5.7 13.6 1.3 8.2 6.4 1.9 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 EER28038.1 - 1.5e-33 115.9 26.9 1.5e-33 115.9 18.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.4 EER28038.1 - 0.011 15.6 2.0 0.011 15.6 1.4 3.6 3 2 1 4 4 4 0 Protein of unknown function (DUF2530) DUF4017 PF13209.1 EER28038.1 - 0.054 13.2 0.5 0.054 13.2 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4017) DUF1616 PF07760.6 EER28038.1 - 0.085 11.9 4.7 0.32 10.0 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1616) Aa_trans PF01490.13 EER28039.1 - 1.1e-22 80.1 27.2 2e-15 56.1 11.9 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein US22 PF02393.11 EER28039.1 - 0.094 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 US22 like p450 PF00067.17 EER28040.1 - 3.3e-60 203.9 0.0 3.7e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EER28041.1 - 7.1e-23 80.7 1.3 1.1e-22 80.1 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28041.1 - 2.1e-08 33.8 8.9 6.5e-08 32.3 6.2 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IncA PF04156.9 EER28042.1 - 0.00069 19.2 18.9 0.0016 18.0 13.1 1.7 1 0 0 1 1 1 1 IncA protein GMP_synt_C PF00958.17 EER28042.1 - 0.057 13.1 0.0 0.087 12.5 0.0 1.7 1 1 0 1 1 1 0 GMP synthase C terminal domain Exonuc_VII_L PF02601.10 EER28042.1 - 0.062 12.4 10.9 0.11 11.6 7.5 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.7 EER28042.1 - 0.58 9.9 30.2 3.6 7.3 20.1 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EER28042.1 - 0.65 9.1 31.8 1.7 7.7 22.1 1.7 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EER28042.1 - 4.9 4.8 14.8 10 3.8 10.3 1.6 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S8 PF00082.17 EER28043.1 - 1.8e-45 155.2 8.5 3.4e-45 154.3 5.9 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER28043.1 - 5.2e-15 55.7 0.0 8.3e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_M14 PF00246.19 EER28044.1 - 4.6e-76 256.0 0.6 6.1e-76 255.6 0.4 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EER28044.1 - 3e-09 36.3 0.1 1e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase activation peptide Fungal_trans PF04082.13 EER28045.1 - 7.7e-20 70.8 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2730 PF10805.3 EER28045.1 - 0.39 10.4 1.5 16 5.2 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Rox3 PF08633.5 EER28046.1 - 1.3e-52 178.9 0.0 1.3e-52 178.9 0.0 1.8 2 1 1 3 3 3 1 Rox3 mediator complex subunit HAD_2 PF13419.1 EER28047.1 - 6.9e-33 114.3 0.0 1e-32 113.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EER28047.1 - 0.024 15.0 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER28047.1 - 0.028 14.1 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4202 PF13875.1 EER28048.1 - 6.9e-83 276.8 0.1 7.7e-83 276.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) VIT1 PF01988.14 EER28049.1 - 3.3e-57 193.3 3.9 4e-57 193.1 2.7 1.1 1 0 0 1 1 1 1 VIT family LSM PF01423.17 EER28050.1 - 3.6e-17 61.6 0.1 4e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EER28050.1 - 0.0021 17.9 0.2 0.0024 17.7 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain VPS9 PF02204.13 EER28052.1 - 3.7e-31 107.2 0.0 6.7e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EER28052.1 - 2.2e-09 36.5 0.1 2.4e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.16 EER28053.1 - 4.4e-52 177.1 0.0 5.8e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EER28053.1 - 1.6e-05 24.6 0.0 0.00011 21.9 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EER28053.1 - 0.0093 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain PH_6 PF15406.1 EER28054.1 - 1.6e-33 115.0 2.8 1.6e-33 115.0 1.9 3.1 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EER28054.1 - 0.0047 17.1 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 PH domain Sulfate_transp PF00916.15 EER28055.1 - 8.2e-39 133.2 3.9 8.2e-39 133.2 2.7 1.9 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EER28055.1 - 2.4e-14 52.9 0.0 4.7e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EER28055.1 - 3.4e-10 39.3 0.1 6.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 EER28056.1 - 2.1e-08 34.4 0.0 3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 EER28056.1 - 0.038 13.5 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) HMG_box PF00505.14 EER28057.1 - 2.4e-10 40.5 0.6 7.5e-10 38.9 0.4 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box PHD PF00628.24 EER28058.1 - 9e-09 34.8 10.4 2e-08 33.7 7.2 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EER28058.1 - 0.15 11.3 9.3 0.028 13.7 3.6 1.9 2 0 0 2 2 2 0 PHD-finger V_ATPase_I PF01496.14 EER28058.1 - 6.1 4.5 11.7 8.8 4.0 8.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PNTB PF02233.11 EER28059.1 - 1e-171 571.8 25.2 1e-171 571.8 17.4 1.7 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EER28059.1 - 1.8e-54 183.8 0.5 3.1e-54 183.0 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EER28059.1 - 8.4e-43 145.6 0.0 2.6e-42 144.0 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EER28059.1 - 1e-30 105.6 4.0 1e-30 105.6 2.8 5.0 4 2 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EER28059.1 - 0.00099 18.3 0.2 2.4 7.2 0.0 3.5 4 0 0 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EER28059.1 - 0.06 12.9 0.0 0.28 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.9 EER28059.1 - 0.067 13.0 1.2 0.15 11.9 0.3 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EER28059.1 - 0.067 12.0 0.6 0.12 11.1 0.5 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_18 PF12847.2 EER28059.1 - 0.1 13.1 0.0 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_8 PF13450.1 EER28059.1 - 4.3 7.4 8.2 1.4 9.0 1.7 3.3 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain bZIP_1 PF00170.16 EER28060.1 - 7.3e-09 35.4 7.5 1.2e-08 34.7 5.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EER28060.1 - 3.4e-05 23.5 9.4 5.7e-05 22.8 6.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Baculo_11_kDa PF06143.6 EER28060.1 - 0.13 11.6 0.1 0.28 10.5 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Rcd1 PF04078.8 EER28061.1 - 8.9e-131 434.4 2.9 1.3e-130 433.9 2.0 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like AP-5_subunit_s1 PF15001.1 EER28061.1 - 0.034 14.0 11.7 0.59 10.0 5.6 2.3 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Spore_coat_CotO PF14153.1 EER28061.1 - 2.5 7.5 12.8 3.4 7.0 8.8 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Androgen_recep PF02166.11 EER28061.1 - 3.5 6.3 16.4 5.4 5.7 11.4 1.2 1 0 0 1 1 1 0 Androgen receptor PAT1 PF09770.4 EER28061.1 - 7.1 4.7 35.9 8.8 4.4 24.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2668 PF10873.3 EER28062.1 - 0.0087 16.2 2.8 0.055 13.6 1.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) DUF4131 PF13567.1 EER28062.1 - 0.027 13.9 0.4 0.05 13.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) F-box-like PF12937.2 EER28063.1 - 1.6e-06 27.7 0.6 7.7e-06 25.5 0.2 2.4 2 0 0 2 2 2 1 F-box-like DIOX_N PF14226.1 EER28065.1 - 9.9e-28 97.0 0.1 1.8e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EER28065.1 - 5.2e-19 68.3 0.0 9e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EER28066.1 - 4.3e-28 97.9 0.9 6.8e-28 97.2 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28066.1 - 0.00011 21.9 11.8 0.00025 20.8 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COesterase PF00135.23 EER28067.1 - 1.7e-76 258.0 0.0 6e-74 249.6 0.0 2.0 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EER28067.1 - 8.8e-11 41.7 0.1 1.8e-10 40.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER28067.1 - 0.00051 19.8 0.0 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Transp_cyt_pur PF02133.10 EER28068.1 - 6.3e-26 90.9 32.6 1.1e-24 86.7 22.6 2.2 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Avian_gp85 PF03708.9 EER28068.1 - 0.09 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Avian retrovirus envelope protein, gp85 Abhydrolase_6 PF12697.2 EER28069.1 - 2.2e-19 70.2 0.6 4.3e-19 69.3 0.4 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER28069.1 - 1.4e-09 37.9 0.0 1.7e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER28069.1 - 7.2e-09 35.5 0.0 7.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.7 EER28069.1 - 0.00012 20.9 0.0 0.00017 20.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) DUF2305 PF10230.4 EER28069.1 - 0.008 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) AXE1 PF05448.7 EER28069.1 - 0.016 13.7 0.0 0.024 13.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 EER28069.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DNase_NucA_NucB PF14040.1 EER28070.1 - 2e-29 102.0 0.5 3.2e-29 101.3 0.3 1.3 1 0 0 1 1 1 1 Deoxyribonuclease NucA/NucB FAD_binding_3 PF01494.14 EER28072.1 - 1.4e-11 44.0 0.1 0.00023 20.3 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 EER28072.1 - 9.1e-05 22.7 0.2 0.049 14.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER28072.1 - 0.00018 21.4 0.1 0.00036 20.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EER28072.1 - 0.0074 16.3 0.0 0.034 14.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EER28072.1 - 0.025 13.5 0.7 0.16 10.8 0.1 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase DUF3188 PF11384.3 EER28072.1 - 0.091 12.3 1.1 4.6 6.8 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Mito_carr PF00153.22 EER28074.1 - 1.6e-57 191.1 1.1 3.2e-20 71.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prefoldin_2 PF01920.15 EER28076.1 - 6.7e-20 70.8 3.9 8.2e-20 70.5 2.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit XhlA PF10779.4 EER28076.1 - 0.0097 15.8 3.4 0.018 14.9 0.6 2.3 1 1 1 2 2 2 1 Haemolysin XhlA Baculo_PEP_C PF04513.7 EER28076.1 - 0.034 13.9 1.3 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 EER28076.1 - 0.042 13.9 4.7 0.044 13.9 0.3 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EER28076.1 - 0.061 13.4 6.8 0.16 12.0 0.3 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pox_A_type_inc PF04508.7 EER28076.1 - 0.078 12.7 0.8 0.9 9.4 0.1 2.6 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat Tropomyosin_1 PF12718.2 EER28076.1 - 0.092 12.5 2.7 0.56 10.0 0.2 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF885 PF05960.6 EER28076.1 - 0.094 11.8 0.1 0.1 11.7 0.1 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF4618 PF15397.1 EER28076.1 - 0.12 11.6 3.2 1.9 7.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2570 PF10828.3 EER28076.1 - 0.2 11.2 3.2 3.7 7.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Vac_Fusion PF02346.11 EER28076.1 - 0.28 10.6 0.1 0.28 10.6 0.1 2.0 3 0 0 3 3 3 0 Chordopoxvirus fusion protein DUF1664 PF07889.7 EER28076.1 - 0.33 10.7 4.4 0.33 10.7 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) FlxA PF14282.1 EER28076.1 - 0.35 10.8 8.9 1.7 8.6 2.3 2.4 2 0 0 2 2 2 0 FlxA-like protein CtIP_N PF10482.4 EER28076.1 - 0.4 10.4 3.3 4.7 7.0 0.1 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ADIP PF11559.3 EER28076.1 - 0.48 10.3 7.7 2.2 8.1 0.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 EER28076.1 - 0.52 9.6 5.2 5.1 6.4 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Prefoldin PF02996.12 EER28076.1 - 0.63 9.7 5.6 11 5.6 3.9 2.1 1 1 0 1 1 1 0 Prefoldin subunit SlyX PF04102.7 EER28076.1 - 1 9.7 4.0 21 5.6 0.0 2.4 2 0 0 2 2 2 0 SlyX Syntaxin PF00804.20 EER28076.1 - 1 9.5 5.8 6.9 6.8 4.0 1.9 1 1 0 1 1 1 0 Syntaxin IncA PF04156.9 EER28076.1 - 1.5 8.3 8.4 27 4.2 5.8 2.0 1 1 0 1 1 1 0 IncA protein DUF3450 PF11932.3 EER28076.1 - 1.9 7.7 5.3 8.6 5.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4600 PF15372.1 EER28076.1 - 1.9 8.7 4.8 5.8 7.1 3.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) DUF2681 PF10883.3 EER28076.1 - 2.2 8.5 5.1 9.4 6.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ATG16 PF08614.6 EER28076.1 - 3.3 7.4 6.6 2.8 7.7 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIC PF04977.10 EER28076.1 - 6.7 6.2 7.8 3.3 7.2 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator Ceramidase PF05875.7 EER28077.1 - 1.4e-105 352.2 12.7 1.7e-105 351.9 8.8 1.1 1 0 0 1 1 1 1 Ceramidase DUF4401 PF14351.1 EER28077.1 - 0.063 12.2 12.7 0.18 10.7 8.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) Abhydrolase_6 PF12697.2 EER28078.1 - 6.4e-25 88.3 0.0 1.2e-24 87.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER28078.1 - 9.5e-05 22.1 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER28078.1 - 0.046 13.2 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EER28078.1 - 0.089 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EER28078.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PTCB-BRCT PF12738.2 EER28079.1 - 9.3e-32 108.6 0.1 4.1e-20 71.4 0.2 4.7 5 0 0 5 5 5 2 twin BRCT domain BRCT PF00533.21 EER28079.1 - 1.3e-29 102.1 0.0 2e-09 37.4 0.0 6.4 6 1 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.7 EER28080.1 - 1.2e-52 177.5 0.0 1.9e-52 176.8 0.0 1.3 2 0 0 2 2 2 1 ESCRT-II complex subunit DUF2786 PF10979.3 EER28081.1 - 2.8e-10 39.7 0.2 6.7e-10 38.5 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) NAD_binding_8 PF13450.1 EER28082.1 - 1.2e-08 34.8 0.5 2.9e-08 33.6 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EER28082.1 - 1.8e-06 27.3 0.1 3.1e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EER28082.1 - 3.4e-05 23.7 0.1 8e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EER28082.1 - 4.4e-05 22.5 0.8 0.00014 20.8 0.7 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EER28082.1 - 0.00037 19.0 0.5 0.0006 18.3 0.4 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EER28082.1 - 0.00045 20.3 0.1 0.0012 18.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EER28082.1 - 0.00093 18.2 1.1 0.0083 15.0 0.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EER28082.1 - 0.005 15.9 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EER28082.1 - 0.0079 16.5 0.2 0.048 14.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EER28082.1 - 0.079 11.7 0.9 0.14 10.9 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A GST_C_2 PF13410.1 EER28082.1 - 0.084 12.7 0.3 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain FAD_binding_3 PF01494.14 EER28083.1 - 3.9e-17 62.3 0.9 2e-16 60.0 0.6 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EER28083.1 - 3.4e-07 30.1 0.1 4.7e-06 26.4 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EER28083.1 - 1.8e-05 23.8 1.7 5.1e-05 22.3 0.8 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER28083.1 - 0.0015 18.4 0.4 0.0037 17.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EER28083.1 - 0.0056 15.3 1.2 0.85 8.1 0.7 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EER28083.1 - 0.033 14.5 0.5 0.07 13.5 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER28083.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EER28083.1 - 0.035 13.0 1.6 3 6.6 0.5 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EER28083.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER28083.1 - 0.055 12.5 0.6 0.093 11.8 0.4 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EER28083.1 - 0.1 12.2 0.9 0.16 11.6 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EER28083.1 - 0.16 10.7 0.0 0.8 8.4 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.19 EER28083.1 - 0.18 10.5 1.5 0.28 9.9 1.1 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EER28083.1 - 0.37 10.1 1.4 0.71 9.2 1.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ketoacyl-synt PF00109.21 EER28084.1 - 1.4e-69 234.4 0.2 2.7e-69 233.4 0.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EER28084.1 - 1.8e-30 106.3 0.2 2.9e-29 102.4 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EER28084.1 - 3.1e-29 101.2 0.1 6.3e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EER28084.1 - 3.9e-27 94.7 0.0 7.2e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EER28084.1 - 2.2e-13 50.5 0.0 6.9e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EER28084.1 - 1e-12 48.0 0.7 3e-12 46.6 0.5 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EER28084.1 - 1e-07 31.6 0.0 3.6e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EER28084.1 - 2e-06 26.9 0.4 8.1e-06 24.9 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.1 EER28084.1 - 3.6e-06 26.7 0.0 1.3e-05 24.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER28084.1 - 6e-06 26.6 0.0 2.2e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EER28084.1 - 2.2e-05 24.4 0.0 9.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EER28084.1 - 5.7e-05 22.6 0.0 0.0001 21.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EER28084.1 - 0.0023 17.6 0.0 0.0064 16.1 0.0 1.8 1 0 0 1 1 1 1 KR domain Methyltransf_18 PF12847.2 EER28084.1 - 0.0032 18.0 0.0 0.021 15.3 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER28084.1 - 0.02 15.2 0.0 0.12 12.7 0.0 2.5 2 0 0 2 2 1 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 EER28084.1 - 0.025 13.4 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RrnaAD PF00398.15 EER28084.1 - 0.03 13.3 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RmlD_sub_bind PF04321.12 EER28084.1 - 0.067 12.0 0.0 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EER28084.1 - 0.3 9.7 0.0 0.75 8.4 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PRD PF00874.15 EER28084.1 - 0.35 11.0 0.3 1.7 8.8 0.1 2.3 2 0 0 2 2 1 0 PRD domain FSH1 PF03959.8 EER28085.1 - 8.3e-36 123.4 0.0 1e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EER28085.1 - 0.00025 20.8 0.1 0.00042 20.0 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER28085.1 - 0.00044 20.2 2.2 0.0028 17.5 1.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EER28085.1 - 0.0014 18.1 0.1 0.17 11.2 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EER28086.1 - 2.9e-22 78.8 44.4 2.9e-22 78.8 30.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily YCII PF03795.9 EER28087.1 - 2.7e-10 40.2 0.0 3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain DIOX_N PF14226.1 EER28088.1 - 9.3e-32 109.9 0.0 1.6e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EER28088.1 - 5.3e-20 71.5 0.0 7.7e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EER28089.1 - 6.5e-20 71.1 4.5 1e-19 70.4 1.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28089.1 - 1.4e-09 37.7 9.0 2.4e-09 36.9 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 EER28090.1 - 5e-14 51.9 0.7 8.4e-14 51.2 0.5 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER28090.1 - 1.3e-10 40.9 0.0 1.3e-09 37.7 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EER28090.1 - 0.0014 18.6 0.1 0.0023 17.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N_2 PF13602.1 EER28090.1 - 0.041 14.7 0.1 0.083 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase YCII PF03795.9 EER28091.1 - 2.5e-09 37.2 0.0 3.2e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain Methyltransf_4 PF02390.12 EER28092.1 - 1.6e-46 157.8 0.0 1.4e-45 154.7 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EER28092.1 - 3.3e-05 24.4 0.0 6.3e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER28092.1 - 0.0012 18.2 0.0 0.053 12.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EER28092.1 - 0.002 18.1 0.0 0.0043 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER28092.1 - 0.025 14.1 0.0 0.072 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 EER28092.1 - 0.026 13.5 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_25 PF13649.1 EER28092.1 - 0.048 14.0 0.0 0.23 11.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EER28092.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain LIM PF00412.17 EER28093.1 - 3.4e-26 91.0 25.9 1.2e-10 41.2 2.4 3.9 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.1 EER28093.1 - 0.065 13.4 0.1 0.065 13.4 0.1 3.1 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain MFS_1 PF07690.11 EER28094.1 - 3.1e-27 95.2 72.3 1.1e-22 80.3 29.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily RNB PF00773.14 EER28095.1 - 1.3e-91 307.3 0.1 1.3e-91 307.3 0.1 1.8 2 1 1 3 3 3 1 RNB domain PIN_4 PF13638.1 EER28095.1 - 4.4e-10 39.7 0.2 1.2e-09 38.4 0.2 1.7 1 0 0 1 1 1 1 PIN domain CN_hydrolase PF00795.17 EER28096.1 - 5.4e-24 84.5 0.0 1e-23 83.6 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ESSS PF10183.4 EER28097.1 - 3.9e-28 97.9 0.1 4.5e-28 97.7 0.1 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ACOX PF01756.14 EER28098.1 - 1.6e-38 131.9 0.0 3.4e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EER28098.1 - 1.2e-29 103.1 1.0 2.3e-29 102.2 0.7 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EER28098.1 - 2.4e-12 46.1 0.8 2.1e-11 43.1 0.2 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EER28098.1 - 1.8e-07 31.3 0.1 0.0018 18.3 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain HTH_31 PF13560.1 EER28098.1 - 0.081 13.1 0.7 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain Beta-lactamase PF00144.19 EER28100.1 - 6.4e-37 127.2 0.1 2.2e-36 125.5 0.0 1.7 1 1 1 2 2 2 1 Beta-lactamase AIP3 PF03915.8 EER28101.1 - 4.4e-161 536.5 9.3 6.7e-161 535.9 6.5 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EER28101.1 - 0.00011 21.5 1.3 0.00038 19.8 0.1 2.6 3 0 0 3 3 3 1 Hepatic lectin, N-terminal domain DivIC PF04977.10 EER28101.1 - 0.014 14.8 1.8 1.2 8.7 0.1 3.7 3 0 0 3 3 3 0 Septum formation initiator GNVR PF13807.1 EER28101.1 - 0.27 11.0 4.7 1.2 8.9 0.0 3.1 3 0 0 3 3 3 0 G-rich domain on putative tyrosine kinase DUF1664 PF07889.7 EER28101.1 - 0.3 10.8 7.1 0.24 11.2 0.5 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LsmAD PF06741.8 EER28102.1 - 1.3e-26 92.4 2.7 1.3e-26 92.4 1.9 2.1 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EER28102.1 - 2.2e-17 62.7 0.0 4.8e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain HEAT PF02985.17 EER28103.1 - 1.4e-09 37.1 1.5 0.13 12.3 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat Pkinase PF00069.20 EER28103.1 - 1.6e-09 37.3 0.0 2.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 EER28103.1 - 5.7e-06 26.6 0.1 0.19 12.2 0.1 3.3 3 0 0 3 3 3 2 HEAT-like repeat Pkinase_Tyr PF07714.12 EER28103.1 - 1e-05 24.7 0.0 1.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EER28103.1 - 4.8e-05 23.5 0.2 0.01 16.1 0.1 3.5 1 1 2 3 3 3 2 HEAT repeats Adaptin_N PF01602.15 EER28103.1 - 0.00084 17.7 0.0 0.093 11.0 0.0 2.2 1 1 0 2 2 2 2 Adaptin N terminal region Kinase-like PF14531.1 EER28103.1 - 0.0086 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.2 EER28103.1 - 0.018 14.9 0.0 0.12 12.2 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EER28103.1 - 0.044 13.1 0.2 0.28 10.4 0.1 2.0 1 1 1 2 2 2 0 CLASP N terminal Vac14_Fab1_bd PF12755.2 EER28103.1 - 0.06 13.7 0.1 8.4 6.8 0.0 2.9 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region CoA_trans PF01144.18 EER28103.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase adh_short PF00106.20 EER28104.1 - 1.1e-15 57.9 0.0 2.3e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER28104.1 - 6e-14 52.3 0.0 9.1e-13 48.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EER28104.1 - 0.00023 20.4 0.0 0.00034 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EER28104.1 - 0.00036 20.2 0.0 0.00066 19.3 0.0 1.5 1 1 0 1 1 1 1 KR domain Dabb PF07876.7 EER28105.1 - 1.1e-20 73.8 0.2 1.2e-20 73.7 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Mtc PF03820.12 EER28105.1 - 0.15 10.7 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier DUF4646 PF15496.1 EER28106.1 - 0.006 16.6 0.3 0.021 14.9 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Spc7 PF08317.6 EER28106.1 - 0.89 8.1 7.9 1.5 7.4 5.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein RmuC PF02646.11 EER28106.1 - 0.9 8.3 9.2 0.39 9.5 3.1 2.3 2 0 0 2 2 2 0 RmuC family DUF3435 PF11917.3 EER28106.1 - 1 8.0 8.4 3 6.4 5.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF342 PF03961.8 EER28106.1 - 2.2 6.6 6.1 4.1 5.6 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Macoilin PF09726.4 EER28106.1 - 2.6 6.2 23.2 0.018 13.3 8.8 2.0 2 0 0 2 2 2 0 Transmembrane protein IncA PF04156.9 EER28106.1 - 3.1 7.3 12.6 0.29 10.6 5.2 1.9 2 0 0 2 2 2 0 IncA protein Acetyltransf_1 PF00583.19 EER28107.1 - 3.8e-14 52.4 0.1 6.2e-14 51.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EER28107.1 - 1.9e-07 30.7 0.1 3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EER28107.1 - 0.0035 17.4 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1793 PF08760.6 EER28107.1 - 0.0075 16.1 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Acetyltransf_9 PF13527.1 EER28107.1 - 0.011 15.5 0.4 0.019 14.8 0.3 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER28107.1 - 0.062 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4066 PF13278.1 EER28109.1 - 9.4e-16 57.5 0.0 1.2e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EER28109.1 - 1.5e-09 37.4 0.0 1.9e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family SUR7 PF06687.7 EER28110.1 - 2.2e-43 148.3 10.0 3.1e-43 147.8 6.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family MFS_1 PF07690.11 EER28110.1 - 0.0088 14.8 11.2 0.0087 14.8 6.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily CCER1 PF15482.1 EER28110.1 - 0.72 9.4 5.5 1.2 8.7 3.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 IncA PF04156.9 EER28110.1 - 1.1 8.8 0.0 1.1 8.8 0.0 2.2 3 0 0 3 3 3 0 IncA protein Prominin PF05478.6 EER28110.1 - 2.5 5.5 6.2 4 4.8 4.3 1.2 1 0 0 1 1 1 0 Prominin SURF6 PF04935.7 EER28111.1 - 0.028 13.6 0.4 0.051 12.8 0.2 1.3 1 0 0 1 1 1 0 Surfeit locus protein 6 DpnD-PcfM PF14207.1 EER28111.1 - 0.044 13.5 0.5 0.12 12.1 0.3 1.6 1 0 0 1 1 1 0 DpnD/PcfM-like protein WD40 PF00400.27 EER28112.1 - 2.5e-47 157.1 17.5 3.1e-11 42.7 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EER28112.1 - 7e-07 27.7 6.8 0.055 11.5 0.1 4.8 2 1 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EER28112.1 - 0.0037 16.0 0.2 0.16 10.6 0.0 2.9 1 1 1 2 2 2 1 Nup133 N terminal like DUF1513 PF07433.6 EER28112.1 - 0.054 12.3 0.2 9.9 4.9 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1513) Tctex-1 PF03645.8 EER28113.1 - 1.5e-32 111.4 0.0 1.9e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF1031 PF06275.6 EER28113.1 - 0.033 14.2 0.0 0.099 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1031) Pkinase PF00069.20 EER28114.1 - 5.2e-11 42.1 0.1 0.00011 21.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF202 PF02656.10 EER28115.1 - 4.5e-12 46.0 5.3 4.5e-12 46.0 3.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4401 PF14351.1 EER28115.1 - 0.039 12.9 3.7 0.022 13.7 1.3 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) DUF2615 PF11027.3 EER28115.1 - 0.18 11.7 0.9 0.31 10.9 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) Metallophos_2 PF12850.2 EER28117.1 - 7.7e-16 58.3 0.0 9.4e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 EER28118.1 - 1.3e-15 56.7 0.0 2.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER28118.1 - 1.9e-13 50.2 0.2 3.7e-13 49.2 0.0 1.6 2 0 0 2 2 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER28118.1 - 8.1e-06 25.5 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IncA PF04156.9 EER28118.1 - 0.02 14.5 1.0 0.025 14.1 0.7 1.1 1 0 0 1 1 1 0 IncA protein CASP_C PF08172.7 EER28118.1 - 0.022 13.7 0.1 0.027 13.4 0.1 1.1 1 0 0 1 1 1 0 CASP C terminal V_ATPase_I PF01496.14 EER28118.1 - 0.036 11.9 0.1 0.043 11.6 0.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spectrin PF00435.16 EER28118.1 - 0.041 14.1 2.5 0.24 11.6 1.9 1.8 1 1 1 2 2 2 0 Spectrin repeat DUF904 PF06005.7 EER28118.1 - 0.11 12.7 4.3 0.18 12.1 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) APG6 PF04111.7 EER28118.1 - 0.13 11.2 0.3 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 EMP24_GP25L PF01105.19 EER28118.1 - 0.17 11.6 0.5 0.23 11.1 0.3 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Pox_A_type_inc PF04508.7 EER28118.1 - 0.17 11.7 1.2 0.48 10.3 0.6 1.9 1 1 1 2 2 2 0 Viral A-type inclusion protein repeat DivIC PF04977.10 EER28118.1 - 0.2 11.1 5.5 0.3 10.5 3.8 1.2 1 0 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.6 EER28118.1 - 0.28 11.1 1.3 0.45 10.4 0.9 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) GRP PF07172.6 EER28118.1 - 1.3 9.5 21.7 0.38 11.2 13.0 1.7 2 0 0 2 2 2 0 Glycine rich protein family HECT PF00632.20 EER28119.1 - 5.8e-95 318.0 0.0 7.9e-95 317.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EER28119.1 - 6.1e-31 105.9 24.4 4e-11 42.5 2.6 4.6 4 0 0 4 4 4 3 WW domain C2 PF00168.25 EER28119.1 - 1e-16 60.5 0.0 2.4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 C2 domain HHH PF00633.18 EER28120.1 - 0.027 14.1 0.2 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Aminotran_5 PF00266.14 EER28121.1 - 8.3e-32 110.3 0.0 1e-31 110.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EER28121.1 - 0.00064 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain OspD PF03207.8 EER28121.1 - 0.026 13.7 0.0 0.042 12.9 0.0 1.3 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) adh_short PF00106.20 EER28121.1 - 0.045 13.6 0.2 0.15 11.9 0.1 1.9 2 0 0 2 2 2 0 short chain dehydrogenase NIF PF03031.13 EER28122.1 - 2.1e-52 176.9 0.0 3.2e-52 176.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BDV_P24 PF06595.6 EER28122.1 - 0.016 14.9 1.8 0.033 13.9 1.3 1.5 1 0 0 1 1 1 0 Borna disease virus P24 protein IF-2B PF01008.12 EER28123.1 - 4.1e-58 196.6 0.0 8.5e-39 133.2 0.1 2.3 2 1 0 2 2 2 2 Initiation factor 2 subunit family DUF2493 PF10686.4 EER28123.1 - 0.018 14.5 0.1 4.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) Ribosom_S12_S23 PF00164.20 EER28124.1 - 7.8e-41 138.3 0.4 9e-41 138.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_L17 PF01196.14 EER28126.1 - 5.1e-33 113.5 0.0 9e-33 112.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 SUZ PF12752.2 EER28127.1 - 1.1e-19 70.6 2.9 1.1e-19 70.6 2.0 3.0 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EER28127.1 - 2.5e-09 36.7 0.0 5.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain cwf18 PF08315.7 EER28129.1 - 7.9e-42 142.7 5.6 7.9e-42 142.7 3.9 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor PPR_2 PF13041.1 EER28130.1 - 3e-09 36.7 1.3 3.4e-05 23.7 0.0 4.1 3 1 1 4 4 4 3 PPR repeat family PPR PF01535.15 EER28130.1 - 9.9e-07 28.3 0.5 0.059 13.3 0.0 4.4 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 EER28130.1 - 3.2e-05 23.8 0.1 3.9 8.0 0.1 5.0 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EER28130.1 - 0.079 12.4 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 PPR repeat DUF1242 PF06842.7 EER28131.1 - 2.4e-19 68.5 0.3 3.5e-19 68.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) PAGK PF15284.1 EER28131.1 - 0.058 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Phage-encoded virulence factor DUF3317 PF11779.3 EER28131.1 - 0.18 11.2 1.0 1.3 8.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3317) TFIID-18kDa PF02269.11 EER28132.1 - 2.8e-23 81.5 0.0 4.6e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EER28132.1 - 7.6e-06 26.0 0.1 1.8e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EER28132.1 - 0.0052 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EER28132.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated JAB PF01398.16 EER28133.1 - 3.7e-17 62.0 0.0 7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EER28133.1 - 2.1e-10 40.6 0.0 4.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.8 EER28133.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) DUF1253 PF06862.7 EER28134.1 - 1e-166 554.7 0.0 1.3e-166 554.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 EER28134.1 - 0.0011 18.4 0.0 0.066 12.7 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase EamA PF00892.15 EER28135.1 - 7.3e-17 61.5 18.7 3.8e-13 49.5 2.2 3.4 3 1 0 3 3 3 3 EamA-like transporter family EmrE PF13536.1 EER28135.1 - 0.0013 18.9 3.3 0.0013 18.9 2.3 3.5 3 1 0 3 3 3 2 Multidrug resistance efflux transporter DUF606 PF04657.8 EER28135.1 - 0.0099 15.9 2.7 0.0099 15.9 1.9 3.1 3 0 0 3 3 3 1 Protein of unknown function, DUF606 TPT PF03151.11 EER28135.1 - 2.8 7.5 11.0 2.3 7.8 2.6 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family CTP_transf_2 PF01467.21 EER28136.1 - 3e-23 82.6 0.2 6e-23 81.6 0.0 1.6 2 0 0 2 2 2 1 Cytidylyltransferase PP2C PF00481.16 EER28137.1 - 2.1e-80 269.8 0.0 2.9e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EER28137.1 - 0.00022 20.6 0.0 0.0005 19.5 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C Acetyltransf_1 PF00583.19 EER28138.1 - 5.4e-17 61.6 0.3 8.2e-17 61.0 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER28138.1 - 1.9e-11 43.9 0.1 2.9e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER28138.1 - 6e-10 39.2 0.1 8.6e-10 38.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER28138.1 - 4.8e-09 35.8 0.1 8e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EER28138.1 - 1.8e-05 24.6 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER28138.1 - 3.2e-05 23.7 0.0 3.9e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER28138.1 - 0.00022 21.0 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 EER28138.1 - 0.0054 16.8 0.1 0.008 16.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EER28138.1 - 0.007 15.9 0.2 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER28138.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZART1 PF12554.3 EER28139.1 - 9.1e-27 92.2 1.4 1.1e-26 92.0 0.9 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated WXG100 PF06013.7 EER28139.1 - 0.0043 17.0 0.0 0.76 9.8 0.0 2.0 2 0 0 2 2 2 2 Proteins of 100 residues with WXG SRP54_N PF02881.14 EER28139.1 - 0.018 15.1 0.1 0.063 13.3 0.0 1.8 1 1 0 2 2 2 0 SRP54-type protein, helical bundle domain CUE PF02845.11 EER28140.1 - 6.8e-11 41.4 0.0 1.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain Pox_Ag35 PF03286.9 EER28140.1 - 1.7 8.1 11.3 4 6.9 0.0 2.4 2 1 0 2 2 2 0 Pox virus Ag35 surface protein OB_NTP_bind PF07717.11 EER28141.1 - 2.4e-23 82.1 0.0 4.5e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EER28141.1 - 1.6e-20 73.0 0.0 3.3e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EER28141.1 - 3.3e-12 46.1 0.0 7e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EER28141.1 - 3e-05 24.1 0.0 8.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EER28141.1 - 5e-05 22.8 0.1 0.00013 21.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase cobW PF02492.14 EER28141.1 - 0.0045 16.4 0.1 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EER28141.1 - 0.0046 16.5 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EER28141.1 - 0.013 15.4 0.1 1.3 8.9 0.0 2.8 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EER28141.1 - 0.023 13.6 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EER28141.1 - 0.039 13.0 0.6 0.2 10.7 0.0 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EER28141.1 - 0.043 13.5 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EER28141.1 - 0.05 13.9 0.3 0.3 11.3 0.0 2.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 EER28141.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PITH PF06201.8 EER28142.1 - 1e-45 155.1 0.0 1.3e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.16 EER28143.1 - 3.6e-35 120.8 5.4 4.7e-35 120.4 3.8 1.1 1 0 0 1 1 1 1 Snf7 MR_MLE_N PF02746.11 EER28143.1 - 0.035 14.1 0.2 0.13 12.2 0.1 2.0 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF2203 PF09969.4 EER28143.1 - 2.2 8.5 4.8 3.5 7.8 0.1 2.4 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) HSCB_C PF07743.8 EER28143.1 - 5.6 7.5 12.8 1 9.8 0.9 2.8 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain Herpes_UL25 PF01499.11 EER28143.1 - 6.3 4.9 8.5 8.6 4.5 3.9 1.9 1 1 1 2 2 2 0 Herpesvirus UL25 family AAA PF00004.24 EER28144.1 - 8.5e-90 297.7 0.0 5.1e-44 149.6 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER28144.1 - 1.4e-14 54.5 0.6 2.1e-06 27.8 0.0 4.0 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 EER28144.1 - 3.4e-13 49.1 0.0 3.9e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EER28144.1 - 4.5e-13 49.4 0.2 0.0034 17.5 0.0 5.4 2 2 2 4 4 4 2 AAA domain AAA_5 PF07728.9 EER28144.1 - 3.5e-11 42.9 0.1 0.00059 19.5 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EER28144.1 - 5.5e-11 42.6 0.0 5.8e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EER28144.1 - 1.9e-10 41.5 0.0 1.9e-05 25.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EER28144.1 - 4e-10 39.7 0.0 0.0002 21.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EER28144.1 - 2.3e-09 37.2 0.0 0.00098 19.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EER28144.1 - 6.5e-09 35.1 0.0 0.0014 17.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EER28144.1 - 1.3e-08 34.0 0.0 0.00015 20.6 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EER28144.1 - 1.9e-08 33.8 0.8 0.0038 16.9 0.1 3.5 2 1 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EER28144.1 - 4.1e-08 33.3 0.0 0.0026 17.9 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EER28144.1 - 2e-07 30.6 0.2 0.018 14.4 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.1 EER28144.1 - 3.3e-07 30.3 0.0 0.0086 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EER28144.1 - 1.1e-06 28.9 0.0 0.012 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EER28144.1 - 1.4e-06 27.6 0.2 0.033 13.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EER28144.1 - 4.8e-06 26.2 0.0 0.016 14.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EER28144.1 - 1.4e-05 24.8 0.5 0.58 9.7 0.0 3.9 3 1 1 4 4 4 2 NACHT domain KaiC PF06745.8 EER28144.1 - 1.9e-05 23.9 0.1 0.32 10.0 0.0 3.1 2 1 1 3 3 3 2 KaiC AAA_25 PF13481.1 EER28144.1 - 2e-05 24.0 6.1 1.8 7.9 0.0 4.9 3 2 2 5 5 5 2 AAA domain Sigma54_activ_2 PF14532.1 EER28144.1 - 2.8e-05 24.1 0.0 0.39 10.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EER28144.1 - 5.4e-05 22.7 0.0 0.23 10.9 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EER28144.1 - 6.2e-05 23.3 0.0 0.25 11.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PhoH PF02562.11 EER28144.1 - 8e-05 21.9 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Cytidylate_kin2 PF13189.1 EER28144.1 - 0.00011 22.1 0.0 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family SKI PF01202.17 EER28144.1 - 0.00016 21.5 0.0 0.49 10.2 0.0 2.6 2 0 0 2 2 2 2 Shikimate kinase Arch_ATPase PF01637.13 EER28144.1 - 0.00047 19.9 0.0 1.6 8.3 0.0 3.6 2 2 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 EER28144.1 - 0.00066 18.6 0.0 0.28 10.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.10 EER28144.1 - 0.0011 17.7 0.0 0.47 9.0 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein ResIII PF04851.10 EER28144.1 - 0.0013 18.6 0.0 2.4 7.9 0.0 2.6 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EER28144.1 - 0.0018 17.1 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.13 EER28144.1 - 0.0025 17.4 0.0 1.6 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AFG1_ATPase PF03969.11 EER28144.1 - 0.0032 16.3 0.0 0.7 8.6 0.0 2.7 3 0 0 3 3 3 1 AFG1-like ATPase AAA_11 PF13086.1 EER28144.1 - 0.0038 16.8 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EER28144.1 - 0.0053 15.7 0.0 0.078 11.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 EER28144.1 - 0.0057 16.2 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EER28144.1 - 0.015 14.9 0.0 2.2 7.9 0.0 3.0 2 1 1 3 3 3 0 NTPase DUF2075 PF09848.4 EER28144.1 - 0.016 14.2 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATP-synt_ab PF00006.20 EER28144.1 - 0.017 14.6 0.0 2 7.8 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.1 EER28144.1 - 0.023 14.3 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EER28144.1 - 0.023 14.3 0.0 0.64 9.6 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein SRPRB PF09439.5 EER28144.1 - 0.13 11.5 0.0 17 4.5 0.0 2.9 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DEAD PF00270.24 EER28144.1 - 0.14 11.6 0.2 46 3.4 0.0 3.3 2 2 0 3 3 3 0 DEAD/DEAH box helicase IPT PF01745.11 EER28144.1 - 0.19 10.8 0.1 15 4.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase DAP3 PF10236.4 EER28144.1 - 0.24 10.2 0.0 20 3.9 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 BOP1NT PF08145.7 EER28145.1 - 6.2e-106 353.8 10.3 8.8e-106 353.3 7.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EER28145.1 - 5.6e-26 89.4 9.9 1.2e-10 40.8 0.1 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat Zn_clus PF00172.13 EER28146.1 - 7.7e-09 35.3 7.1 1.6e-08 34.2 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Leo1 PF04004.8 EER28147.1 - 1.8e-34 118.9 0.0 3.3e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Leo1-like protein Mob1_phocein PF03637.12 EER28148.1 - 3.5e-29 101.6 3.6 4.4e-14 52.5 0.6 2.3 2 0 0 2 2 2 2 Mob1/phocein family ATG16 PF08614.6 EER28149.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Rhomboid PF01694.17 EER28150.1 - 2.3e-16 60.1 3.3 4.6e-16 59.1 2.3 1.4 1 0 0 1 1 1 1 Rhomboid family Trypan_PARP PF05887.6 EER28151.1 - 0.088 12.6 8.0 0.1 12.4 5.1 1.4 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PRCC PF10253.4 EER28151.1 - 0.41 11.3 7.6 0.46 11.1 5.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pex16 PF08610.5 EER28151.1 - 1.8 7.4 5.4 1.9 7.4 3.8 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF605 PF04652.11 EER28151.1 - 4 6.7 12.7 4.6 6.5 8.8 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EER28151.1 - 4.2 5.4 18.9 4.5 5.3 13.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neisseria_TspB PF05616.8 EER28151.1 - 9.6 4.4 6.8 11 4.2 4.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein PhoD PF09423.5 EER28152.1 - 8.5e-10 37.7 0.0 2.1e-07 29.8 0.0 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase Pkinase PF00069.20 EER28153.1 - 7.5e-10 38.3 0.0 1.6e-09 37.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain RIO1 PF01163.17 EER28153.1 - 0.0045 16.3 0.0 0.0092 15.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EER28153.1 - 0.0092 15.0 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER28153.1 - 0.092 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EER28154.1 - 5.7e-24 84.6 0.0 8.8e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER28154.1 - 1.2e-05 24.4 0.0 3.7e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EER28154.1 - 0.025 14.3 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Gryzun PF07919.7 EER28158.1 - 1.4e-132 442.8 0.2 1.8e-132 442.5 0.1 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EER28158.1 - 7.9e-89 297.3 0.6 7.8e-79 264.6 1.5 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EER28158.1 - 0.0032 17.2 0.0 0.0087 15.8 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 EER28159.1 - 6.9e-20 71.9 1.3 3.3e-19 69.6 0.9 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER28159.1 - 2.2e-08 33.9 0.0 1.9e-06 27.6 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER28159.1 - 1.1e-07 31.6 0.0 3.4e-07 30.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glutaredoxin PF00462.19 EER28160.1 - 3.7e-14 52.4 0.0 9.7e-14 51.1 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin GST_N_3 PF13417.1 EER28160.1 - 0.0026 17.9 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L6 PF00347.18 EER28161.1 - 4.6e-23 81.4 6.6 3.3e-12 46.7 0.7 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DUF3336 PF11815.3 EER28162.1 - 8.4e-30 103.1 0.0 1.4e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EER28162.1 - 1.4e-14 54.5 0.2 2.7e-14 53.5 0.0 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase RXT2_N PF08595.6 EER28163.1 - 2.7e-35 121.3 0.0 2.7e-35 121.3 0.0 2.1 2 1 0 2 2 2 1 RXT2-like, N-terminal Disaggr_repeat PF06848.6 EER28163.1 - 0.037 13.4 0.1 0.072 12.5 0.1 1.4 1 0 0 1 1 1 0 Disaggregatase related repeat PEMT PF04191.8 EER28164.1 - 2.4e-31 107.9 3.8 2.4e-31 107.9 2.6 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase KdgT PF03812.8 EER28164.1 - 0.03 13.4 0.3 0.039 13.1 0.2 1.3 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease PXA PF02194.10 EER28165.1 - 8.3e-50 168.9 0.2 8.3e-50 168.9 0.1 2.3 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EER28165.1 - 4.8e-28 97.5 1.9 2e-27 95.5 0.0 2.6 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EER28165.1 - 3e-21 75.3 0.2 7e-21 74.1 0.2 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EER28165.1 - 4.1e-10 39.7 0.0 1.1e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain Aldo_ket_red PF00248.16 EER28167.1 - 1.8e-60 204.1 0.2 2.4e-60 203.7 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family 7TM_GPCR_Srd PF10317.4 EER28167.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd WD40 PF00400.27 EER28168.1 - 1.9e-25 87.7 10.2 3.1e-07 30.0 0.1 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat tRNA-synt_1g PF09334.6 EER28169.1 - 6.4e-142 472.8 0.0 8.5e-142 472.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EER28169.1 - 2e-08 32.7 0.4 2.2e-05 22.7 0.0 3.3 2 2 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) RNase_H2-Ydr279 PF09468.5 EER28169.1 - 0.046 12.9 2.6 0.071 12.2 1.8 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) BRF1 PF07741.8 EER28169.1 - 0.35 11.1 8.9 0.83 9.9 6.2 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Elongin_A PF06881.6 EER28169.1 - 0.68 10.3 7.2 0.32 11.3 3.0 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A NARP1 PF12569.3 EER28169.1 - 8.7 4.9 11.9 14 4.2 8.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Yae1_N PF09811.4 EER28170.1 - 1.5e-05 24.4 3.9 1.5e-05 24.4 2.7 1.7 2 0 0 2 2 2 1 Essential protein Yae1, N terminal UPF0160 PF03690.8 EER28171.1 - 1.3e-111 373.1 0.0 1.5e-111 372.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.5 EER28172.1 - 9.9e-144 478.9 13.4 1.1e-143 478.7 9.3 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.12 EER28173.1 - 5.4e-21 74.3 0.0 8.9e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 EER28174.1 - 1.3e-40 138.9 0.0 1.5e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF550 PF04447.7 EER28174.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF550) tRNA_m1G_MT PF01746.16 EER28174.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase Peptidase_S10 PF00450.17 EER28175.1 - 9.4e-117 390.6 0.0 1.3e-116 390.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Act-Frag_cataly PF09192.5 EER28175.1 - 0.031 13.2 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic WD40 PF00400.27 EER28176.1 - 1.6e-50 167.2 20.4 1.9e-10 40.2 0.0 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EER28176.1 - 0.0031 16.9 0.0 1.8 8.1 0.0 3.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EER28176.1 - 0.09 11.5 0.2 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Coatomer WD associated region IKI3 PF04762.7 EER28176.1 - 0.79 7.4 3.7 3.8 5.2 0.4 2.4 2 1 0 2 2 2 0 IKI3 family MHYT PF03707.11 EER28177.1 - 1.9e-07 31.0 24.8 7.3e-05 22.8 2.4 4.7 4 1 0 4 4 4 2 Bacterial signalling protein N terminal repeat Bestrophin PF01062.16 EER28177.1 - 0.33 9.8 4.2 0.49 9.2 0.7 2.2 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel Tcp11 PF05794.8 EER28178.1 - 7.6e-50 169.8 0.0 8.6e-49 166.4 0.0 2.2 1 1 0 1 1 1 1 T-complex protein 11 IQ PF00612.22 EER28178.1 - 0.0061 16.0 0.9 0.021 14.4 0.6 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DUF1446 PF07287.6 EER28179.1 - 5.4e-117 390.3 0.0 6.4e-117 390.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) HMA PF00403.21 EER28180.1 - 3.5e-16 59.0 0.6 4.3e-16 58.7 0.4 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF2293 PF10056.4 EER28181.1 - 6.9e-29 99.6 0.1 1.6e-28 98.4 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Complex1_LYR PF05347.10 EER28182.1 - 2.8e-07 30.2 1.7 4.9e-07 29.4 0.9 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EER28182.1 - 0.0017 18.4 1.1 0.003 17.7 0.7 1.5 1 0 0 1 1 1 1 Complex1_LYR-like zinc_ribbon_6 PF14599.1 EER28183.1 - 1.8e-26 91.7 1.2 1.8e-26 91.7 0.9 3.8 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EER28183.1 - 3.2e-15 56.0 22.5 3.2e-15 56.0 15.6 4.3 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EER28183.1 - 5.9e-09 35.6 8.4 5.9e-09 35.6 5.8 4.2 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EER28183.1 - 1.1e-07 31.8 7.3 1.1e-07 31.8 5.1 5.0 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER28183.1 - 4.1e-07 29.5 7.2 4.1e-07 29.5 5.0 5.2 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER28183.1 - 7.4e-06 25.5 8.3 7.4e-06 25.5 5.7 6.8 5 3 1 6 6 6 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EER28183.1 - 0.0056 16.3 2.1 0.0056 16.3 1.5 6.2 3 3 2 5 5 5 2 Prokaryotic RING finger family 1 Rrn6 PF10214.4 EER28184.1 - 1.8e-118 396.7 0.0 2.8e-118 396.1 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EER28185.1 - 4.2e-22 77.9 0.3 1.1e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Peptidase_S46 PF10459.4 EER28185.1 - 0.036 12.4 8.6 0.04 12.3 6.0 1.0 1 0 0 1 1 1 0 Peptidase S46 THOC7 PF05615.8 EER28185.1 - 0.52 10.5 14.7 0.24 11.6 8.3 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 UPF0560 PF10577.4 EER28185.1 - 0.74 7.9 4.8 0.97 7.6 3.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Peripla_BP_2 PF01497.13 EER28185.1 - 0.98 8.4 5.8 1.7 7.7 4.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Filament PF00038.16 EER28185.1 - 2.8 7.3 21.0 16 4.8 14.5 1.9 1 1 0 1 1 1 0 Intermediate filament protein V_ATPase_I PF01496.14 EER28185.1 - 5.3 4.7 6.4 6.4 4.4 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 EER28185.1 - 7.9 4.7 7.4 7.7 4.8 5.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mnd1 PF03962.10 EER28185.1 - 8.1 6.0 16.4 0.99 9.0 2.4 2.1 1 1 1 2 2 2 0 Mnd1 family WD40 PF00400.27 EER28186.1 - 7.2e-32 108.1 18.2 3.2e-12 45.8 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Ribosomal_L32p PF01783.18 EER28186.1 - 7.8e-11 41.9 7.1 1.4e-10 41.1 4.9 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family Cytochrom_D1 PF02239.11 EER28186.1 - 0.00059 18.2 0.0 0.053 11.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EER28186.1 - 0.0016 18.1 0.0 0.16 11.7 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EER28186.1 - 0.012 13.8 0.2 0.42 8.6 0.0 2.5 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Hira PF07569.6 EER28186.1 - 0.015 14.5 0.3 0.2 10.8 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split Stc1 PF12898.2 EER28186.1 - 0.021 14.8 0.2 0.05 13.6 0.1 1.7 1 1 0 1 1 1 0 Stc1 domain Septin PF00735.13 EER28187.1 - 1.8e-112 374.9 0.5 2.1e-112 374.7 0.4 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EER28187.1 - 5.3e-07 29.6 0.0 9.8e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EER28187.1 - 8.7e-06 24.9 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EER28187.1 - 4.4e-05 22.7 0.0 7.5e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EER28187.1 - 0.00014 21.7 0.3 0.5 10.1 0.1 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EER28187.1 - 0.00076 18.9 0.4 0.015 14.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 EER28187.1 - 0.0022 17.4 0.2 0.0022 17.4 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EER28187.1 - 0.003 17.8 0.0 0.0054 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EER28187.1 - 0.0076 16.5 0.3 0.018 15.3 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EER28187.1 - 0.017 15.2 0.0 0.035 14.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EER28187.1 - 0.021 13.6 0.0 0.038 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Gtr1_RagA PF04670.7 EER28187.1 - 0.028 13.5 0.1 0.097 11.8 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EER28187.1 - 0.028 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EER28187.1 - 0.061 12.2 0.1 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 EER28187.1 - 0.062 13.7 0.1 0.24 11.9 0.0 1.9 1 1 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 EER28187.1 - 0.067 13.1 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EER28187.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 EER28188.1 - 6.1e-65 218.0 0.0 6.9e-65 217.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EER28188.1 - 6.2e-06 26.3 0.1 2.8e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EER28188.1 - 6.3e-06 26.5 0.4 6.4e-05 23.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER28188.1 - 2.4e-05 24.2 0.0 0.00019 21.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EER28188.1 - 3.2e-05 23.8 0.0 5.9e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EER28188.1 - 8.3e-05 22.7 0.0 0.00029 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER28188.1 - 8.8e-05 23.3 0.3 0.00022 22.0 0.2 2.0 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 EER28188.1 - 0.00076 19.9 0.0 0.0016 18.9 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EER28188.1 - 0.0015 18.8 0.0 0.0036 17.6 0.0 1.6 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EER28188.1 - 0.002 17.3 0.0 0.0032 16.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EER28188.1 - 0.0029 17.5 0.0 0.0068 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EER28188.1 - 0.0041 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EER28188.1 - 0.0045 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EER28188.1 - 0.0047 16.8 0.1 0.013 15.4 0.0 1.8 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.1 EER28188.1 - 0.0065 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EER28188.1 - 0.008 15.1 0.0 0.017 14.0 0.0 1.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.24 EER28188.1 - 0.013 15.7 0.1 0.025 14.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EER28188.1 - 0.02 14.5 0.0 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_5 PF07728.9 EER28188.1 - 0.022 14.4 0.0 0.082 12.6 0.0 2.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EER28188.1 - 0.026 13.2 0.0 0.03 13.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF2075 PF09848.4 EER28188.1 - 0.027 13.4 0.0 0.16 10.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EER28188.1 - 0.027 14.1 0.1 0.051 13.2 0.1 1.6 1 1 0 1 1 1 0 NTPase NACHT PF05729.7 EER28188.1 - 0.033 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.1 EER28188.1 - 0.037 13.5 0.0 0.089 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EER28188.1 - 0.039 13.5 0.0 0.07 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EER28188.1 - 0.051 12.7 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 EER28188.1 - 0.054 13.8 2.9 0.11 12.7 2.0 1.8 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EER28188.1 - 0.059 12.7 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras family Pox_A32 PF04665.7 EER28188.1 - 0.069 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_10 PF12846.2 EER28188.1 - 0.073 12.4 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain GRAB PF10375.4 EER28189.1 - 3e-07 29.8 0.3 6e-07 28.8 0.2 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EER28189.1 - 0.00019 20.7 13.5 0.023 13.9 4.2 2.1 1 1 0 2 2 2 2 Reovirus sigma C capsid protein COG5 PF10392.4 EER28189.1 - 0.046 13.6 18.5 0.082 12.8 5.8 3.2 2 2 0 2 2 2 0 Golgi transport complex subunit 5 Baculo_PEP_C PF04513.7 EER28189.1 - 5.3 6.8 19.7 0.92 9.3 1.7 3.4 2 2 2 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF814 PF05670.8 EER28190.1 - 2.5e-13 49.7 0.0 4.9e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF814) CENP-X PF09415.5 EER28191.1 - 0.14 11.9 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pkinase PF00069.20 EER28192.1 - 5.2e-12 45.4 0.0 7e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DAO PF01266.19 EER28193.1 - 2e-48 165.1 0.0 2.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EER28193.1 - 2.2e-11 43.2 0.3 4.4e-11 42.2 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EER28193.1 - 1.7e-07 30.7 0.2 8.1e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EER28193.1 - 0.00035 20.5 0.1 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EER28193.1 - 0.00084 19.0 0.3 0.0016 18.1 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EER28193.1 - 0.0022 17.9 0.1 0.0098 15.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EER28193.1 - 0.0037 16.4 0.2 0.13 11.3 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EER28193.1 - 0.014 15.8 0.1 0.095 13.1 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EER28193.1 - 0.024 13.1 0.6 0.04 12.4 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EER28193.1 - 0.034 14.1 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EER28193.1 - 0.047 12.5 0.5 0.28 10.0 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EER28193.1 - 0.048 12.5 0.2 0.099 11.5 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EER28193.1 - 0.073 12.1 0.2 0.75 8.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain p450 PF00067.17 EER28194.1 - 4.8e-66 223.1 0.0 5.5e-66 222.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DASH_Dad2 PF08654.5 EER28196.1 - 1.3e-33 115.0 0.5 1.5e-33 114.8 0.3 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad2 Shugoshin_N PF07558.6 EER28197.1 - 4.8e-17 61.3 3.1 1.2e-16 60.0 2.1 1.8 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EER28197.1 - 3.1e-08 32.9 6.2 3.1e-08 32.9 4.3 2.8 3 0 0 3 3 3 1 Shugoshin C terminus bZIP_1 PF00170.16 EER28197.1 - 0.021 14.7 1.0 0.021 14.7 0.7 2.3 2 0 0 2 2 2 0 bZIP transcription factor Mod_r PF07200.8 EER28197.1 - 0.13 12.1 3.9 0.058 13.3 0.8 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF904 PF06005.7 EER28197.1 - 0.14 12.4 0.7 0.39 11.0 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) PPI_Ypi1 PF07491.6 EER28198.1 - 2.6e-24 84.5 6.1 2.6e-24 84.5 4.3 2.1 2 1 0 2 2 2 1 Protein phosphatase inhibitor TFIIF_alpha PF05793.7 EER28198.1 - 0.042 12.2 8.7 0.05 11.9 6.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Menin PF05053.8 EER28198.1 - 0.5 8.4 3.4 0.59 8.2 2.4 1.0 1 0 0 1 1 1 0 Menin Macoilin PF09726.4 EER28198.1 - 3.6 5.7 6.7 4 5.6 4.6 1.0 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 EER28198.1 - 3.7 5.4 7.6 4 5.3 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CRM1_C PF08767.6 EER28200.1 - 1.5e-134 447.8 9.7 1.5e-134 447.8 6.8 3.3 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EER28200.1 - 7.9e-42 142.6 10.4 2.7e-41 140.9 4.9 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EER28200.1 - 7.3e-12 45.0 0.3 3.3e-11 42.9 0.2 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 EER28200.1 - 0.0055 16.9 0.4 9.4 6.5 0.1 4.0 3 0 0 3 3 3 2 Phosphohydrolase-associated domain FAD_binding_3 PF01494.14 EER28201.1 - 6.9e-19 68.0 0.0 5.1e-18 65.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EER28201.1 - 4.1e-10 39.1 0.1 8e-06 24.9 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EER28201.1 - 2e-08 33.7 0.0 2.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER28201.1 - 2.7e-07 30.5 0.8 6.1e-07 29.3 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EER28201.1 - 1.9e-06 27.0 5.2 4.4e-06 25.8 3.6 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EER28201.1 - 9.1e-06 24.3 0.7 0.00073 18.1 1.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EER28201.1 - 3.8e-05 22.7 0.5 0.11 11.4 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EER28201.1 - 4.2e-05 23.5 3.3 0.00031 20.6 2.3 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER28201.1 - 5.9e-05 23.3 4.2 0.0021 18.4 1.5 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EER28201.1 - 6.4e-05 21.9 1.7 9.7e-05 21.3 1.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EER28201.1 - 0.00024 19.8 2.7 0.076 11.6 1.2 2.1 1 1 1 2 2 2 2 Tryptophan halogenase Thi4 PF01946.12 EER28201.1 - 0.00093 18.3 0.3 0.0016 17.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 EER28201.1 - 0.004 16.0 0.0 0.0067 15.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase 3HCDH_N PF02737.13 EER28201.1 - 0.014 15.0 1.7 0.026 14.1 1.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EER28201.1 - 0.017 15.2 0.0 0.031 14.3 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EER28201.1 - 0.058 12.4 0.8 0.44 9.5 0.5 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 EER28201.1 - 0.12 12.0 0.5 0.22 11.2 0.4 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EER28201.1 - 0.18 11.2 0.3 0.36 10.1 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EER28201.1 - 0.3 10.6 0.9 0.7 9.4 0.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Hexapep PF00132.19 EER28202.1 - 1.3e-13 49.7 7.2 4.1e-08 32.3 0.5 3.7 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EER28202.1 - 3.3e-12 46.2 0.0 7.7e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Maltose acetyltransferase Zn_clus PF00172.13 EER28202.1 - 9.6e-11 41.4 9.5 2e-10 40.4 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 EER28202.1 - 3.8e-08 32.7 6.5 2e-06 27.2 0.4 3.4 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase ALAD PF00490.16 EER28203.1 - 1.5e-117 392.1 0.0 1.7e-117 391.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CIAPIN1 PF05093.8 EER28204.1 - 6.3e-35 119.2 2.7 9e-35 118.7 1.9 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Nucleoporin_C PF03177.9 EER28205.1 - 1.7e-95 320.7 0.9 2e-95 320.5 0.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EER28205.1 - 3.7e-54 184.1 0.0 4.7e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like SHNi-TPR PF10516.4 EER28206.1 - 3.6e-15 54.9 5.1 1.1e-14 53.3 0.0 3.4 3 1 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 EER28206.1 - 8.7e-09 35.2 3.1 0.00037 20.3 1.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EER28206.1 - 2e-06 27.3 4.4 0.03 13.9 0.0 3.1 3 1 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 EER28206.1 - 0.0043 17.7 2.5 0.16 12.6 0.4 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat PMBR PF09373.5 EER28206.1 - 0.0095 15.8 0.0 0.033 14.1 0.0 2.0 1 0 0 1 1 1 1 Pseudomurein-binding repeat Serine_rich PF08824.5 EER28206.1 - 0.031 13.9 0.0 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain TPR_1 PF00515.23 EER28206.1 - 0.031 13.8 5.0 0.49 10.0 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Adaptin_binding PF10199.4 EER28206.1 - 0.22 11.8 8.5 0.043 14.0 2.8 2.1 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TPR_10 PF13374.1 EER28206.1 - 0.4 10.6 2.4 5.8 6.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF848 PF05852.6 EER28206.1 - 1.3 8.8 6.5 1.1 9.1 0.2 3.3 4 0 0 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) TPR_2 PF07719.12 EER28206.1 - 2.2 8.3 16.9 4.6 7.3 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EER28206.1 - 3.9 8.3 5.5 8.9 7.2 0.3 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ThiF PF00899.16 EER28207.1 - 5.2e-28 97.5 0.0 8.5e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EER28207.1 - 0.024 14.7 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thioredoxin PF00085.15 EER28208.1 - 4.4e-63 209.4 3.3 2.2e-31 107.6 0.1 4.0 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EER28208.1 - 1.5e-52 178.0 5.5 1.4e-38 132.5 1.0 3.6 3 1 1 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.12 EER28208.1 - 8.5e-12 44.5 0.8 1.9e-11 43.3 0.6 1.5 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_2 PF13098.1 EER28208.1 - 1.8e-10 40.9 1.3 0.00084 19.5 0.1 3.7 3 2 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EER28208.1 - 5.9e-10 39.0 0.0 0.00019 21.3 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EER28208.1 - 1.7e-09 37.6 0.0 0.003 17.6 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 EER28208.1 - 4.2e-06 26.4 0.2 0.046 13.4 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EER28208.1 - 4.7e-05 22.9 0.2 0.034 13.6 0.0 2.7 2 0 0 2 2 2 2 Redoxin Thioredoxin_4 PF13462.1 EER28208.1 - 0.0029 17.6 2.4 6.6 6.7 0.0 3.7 3 0 0 3 3 3 1 Thioredoxin His_biosynth PF00977.16 EER28209.1 - 1.6e-46 158.4 0.3 6.8e-46 156.3 0.2 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EER28209.1 - 1.9e-28 99.2 0.0 3e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EER28209.1 - 1.3e-10 41.0 0.0 2.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EER28209.1 - 1.2e-09 38.0 0.0 9.2e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 EER28209.1 - 0.0041 16.5 0.0 0.017 14.5 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 DUF2156 PF09924.4 EER28209.1 - 0.11 11.3 0.1 4.3 6.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2156) HNH_2 PF13391.1 EER28210.1 - 3e-08 33.3 0.0 6.4e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Tri3 PF07428.6 EER28210.1 - 0.05 12.3 0.1 0.073 11.7 0.0 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 UCH PF00443.24 EER28211.1 - 4.5e-42 144.0 0.0 7.9e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EER28211.1 - 1.1e-22 79.9 21.5 3.8e-19 68.5 1.9 4.4 4 1 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EER28211.1 - 5.2e-19 68.7 0.0 3.8e-18 65.9 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EER28211.1 - 5.5e-19 67.4 0.1 4e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain dCMP_cyt_deam_1 PF00383.17 EER28213.1 - 3.8e-27 93.9 3.5 7.2e-27 93.0 2.4 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 EER28213.1 - 0.011 16.0 0.0 0.097 12.9 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EER28213.1 - 0.15 12.9 0.0 0.29 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain SAS4 PF15460.1 EER28214.1 - 7.9e-32 109.1 2.8 7.9e-32 109.1 1.9 1.7 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 RPN7 PF10602.4 EER28215.1 - 6.4e-54 181.9 0.8 1.3e-53 180.9 0.2 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EER28215.1 - 2.8e-09 37.2 1.6 6.9e-09 35.9 0.3 2.3 2 1 0 2 2 2 1 PCI domain TPR_1 PF00515.23 EER28215.1 - 0.2 11.3 1.5 24 4.7 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC_membrane PF00664.18 EER28216.1 - 2.1e-70 237.2 33.6 1e-35 123.5 10.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EER28216.1 - 9.4e-56 187.9 0.0 1.5e-26 93.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EER28216.1 - 4.6e-14 52.1 4.1 3.3e-05 23.2 0.0 4.6 4 1 1 5 5 5 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER28216.1 - 2.1e-10 41.0 0.4 0.0066 16.4 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EER28216.1 - 1e-09 37.7 0.3 0.00067 19.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EER28216.1 - 2.1e-08 34.3 0.4 0.0062 16.6 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EER28216.1 - 2.5e-07 31.5 0.0 0.035 14.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EER28216.1 - 6.6e-07 28.6 0.1 0.056 12.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EER28216.1 - 6.8e-07 28.8 0.0 0.064 12.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EER28216.1 - 1.3e-06 28.4 1.3 0.083 12.8 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EER28216.1 - 2.6e-06 26.2 0.8 0.036 12.6 0.1 3.7 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_10 PF12846.2 EER28216.1 - 6.7e-06 25.7 3.9 0.023 14.1 0.1 3.9 4 0 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 EER28216.1 - 3.8e-05 23.9 0.1 0.42 10.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EER28216.1 - 0.00024 21.4 1.0 0.087 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.1 EER28216.1 - 0.0005 18.7 0.0 0.22 10.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) FtsK_SpoIIIE PF01580.13 EER28216.1 - 0.00088 18.8 0.1 1 8.8 0.0 2.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EER28216.1 - 0.002 18.0 0.8 0.95 9.4 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 EER28216.1 - 0.0029 17.4 1.9 1.3 8.7 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_19 PF13245.1 EER28216.1 - 0.0035 17.0 0.4 0.65 9.7 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 EER28216.1 - 0.0043 16.7 0.2 2.8 7.6 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EER28216.1 - 0.0067 16.3 0.2 2.8 7.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EER28216.1 - 0.013 14.3 0.1 0.83 8.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 EER28216.1 - 0.017 13.9 0.1 4.1 6.2 0.0 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein SbcCD_C PF13558.1 EER28216.1 - 0.035 14.0 0.9 0.59 10.0 0.1 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 EER28216.1 - 0.037 13.6 0.2 8 5.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EER28216.1 - 0.037 13.7 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 EER28216.1 - 0.039 13.1 0.3 4.9 6.3 0.0 3.1 3 0 0 3 3 3 0 PhoH-like protein KaiC PF06745.8 EER28216.1 - 0.068 12.2 2.3 2.7 7.0 0.0 2.9 3 0 0 3 3 3 0 KaiC CbiA PF01656.18 EER28216.1 - 0.095 12.0 1.5 1.8 7.8 0.2 2.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain APS_kinase PF01583.15 EER28216.1 - 0.13 11.9 0.0 22 4.6 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EER28216.1 - 0.19 11.9 0.1 25 5.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 EER28216.1 - 0.3 10.1 0.1 20 4.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AIG1 PF04548.11 EER28216.1 - 0.87 8.6 2.3 4.8 6.2 0.1 2.8 4 0 0 4 4 2 0 AIG1 family AAA_13 PF13166.1 EER28216.1 - 0.87 7.9 0.6 9 4.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain OTT_1508_deam PF14441.1 EER28217.1 - 1.4e-11 44.3 0.0 2.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase CHAD PF05235.9 EER28217.1 - 1.4 8.4 8.0 1.8 8.0 0.4 2.8 2 1 1 3 3 3 0 CHAD domain Kdo PF06293.9 EER28219.1 - 0.00055 19.0 0.0 0.00073 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EER28219.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Rifin_STEVOR PF02009.11 EER28220.1 - 0.033 13.8 0.4 0.065 12.8 0.3 1.4 1 0 0 1 1 1 0 Rifin/stevor family DUF1180 PF06679.7 EER28220.1 - 0.043 13.7 0.1 0.043 13.7 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) DUF912 PF06024.7 EER28220.1 - 0.082 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2254 PF10011.4 EER28220.1 - 0.1 11.0 0.1 0.19 10.1 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF3377 PF11857.3 EER28220.1 - 0.15 11.7 1.2 0.24 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) 7tm_2 PF00002.19 EER28220.1 - 0.24 10.4 0.9 0.37 9.8 0.6 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) OAD_gamma PF04277.8 EER28220.1 - 0.73 10.2 2.3 3.6 8.0 1.6 2.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain RSN1_TM PF13967.1 EER28220.1 - 3.4 7.2 5.1 0.29 10.6 0.3 1.6 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport adh_short PF00106.20 EER28221.1 - 5.2e-15 55.7 0.0 1.6e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER28221.1 - 8e-08 32.3 0.0 1.1e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER28221.1 - 0.088 12.4 0.2 12 5.5 0.3 2.6 2 1 0 2 2 2 0 KR domain TPP_enzyme_C PF02775.16 EER28222.1 - 2.2e-25 88.9 0.0 4.9e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EER28222.1 - 2.8e-23 82.1 0.0 4.7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 EER28222.1 - 2.7e-22 79.0 0.0 1.5e-21 76.6 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain DUF498 PF04430.9 EER28222.1 - 0.02 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Cep57_MT_bd PF06657.8 EER28223.1 - 1.3e-28 98.7 0.8 1.3e-28 98.7 0.5 2.6 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EER28223.1 - 3.5e-18 65.2 5.1 3.5e-18 65.2 3.6 3.9 3 0 0 3 3 3 1 Centrosome localisation domain of PPC89 HALZ PF02183.13 EER28223.1 - 0.0003 20.4 1.4 0.0003 20.4 1.0 3.6 4 0 0 4 4 4 2 Homeobox associated leucine zipper IncA PF04156.9 EER28223.1 - 3.2 7.3 15.1 0.46 10.0 0.8 3.6 3 0 0 3 3 3 0 IncA protein MAT1 PF06391.8 EER28224.1 - 7.6e-40 136.6 10.0 9.6e-40 136.3 7.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EER28224.1 - 0.00019 20.9 3.1 0.00053 19.5 2.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER28224.1 - 0.0019 17.7 5.5 0.0036 16.9 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER28224.1 - 0.0073 16.3 5.5 0.017 15.1 3.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER28224.1 - 0.048 13.3 9.1 0.77 9.5 6.8 2.2 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.1 EER28224.1 - 0.1 12.4 5.8 0.25 11.1 4.0 1.6 1 1 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 EER28224.1 - 0.27 10.8 6.4 0.78 9.3 1.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Iron_permease PF04120.7 EER28225.1 - 0.086 12.4 0.1 0.2 11.2 0.1 1.5 1 0 0 1 1 1 0 Low affinity iron permease HRXXH PF13933.1 EER28226.1 - 3.3e-103 344.3 0.0 4e-103 344.1 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Zip PF02535.17 EER28227.1 - 5.8e-37 127.3 15.1 5.8e-37 127.3 10.5 1.6 2 0 0 2 2 2 1 ZIP Zinc transporter HupE_UreJ PF04955.7 EER28227.1 - 7.7e-05 22.0 11.2 0.00012 21.4 1.4 2.7 2 0 0 2 2 2 2 HupE / UreJ protein Prefoldin_3 PF13758.1 EER28228.1 - 1.6e-35 120.7 2.3 1.6e-35 120.7 1.6 2.7 3 0 0 3 3 3 1 Prefoldin subunit DUF3835 PF12927.2 EER28228.1 - 2e-20 73.5 1.6 2e-20 73.5 1.1 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3835) MerR-DNA-bind PF09278.6 EER28228.1 - 0.0022 18.3 1.8 1.8 9.0 0.1 2.8 2 0 0 2 2 2 2 MerR, DNA binding Prefoldin_2 PF01920.15 EER28228.1 - 3.8 7.3 8.5 7.1 6.4 0.1 3.1 4 0 0 4 4 4 0 Prefoldin subunit Tropomyosin_1 PF12718.2 EER28228.1 - 5.1 6.9 8.5 5.6 6.8 2.2 2.9 2 1 0 2 2 2 0 Tropomyosin like Pkinase PF00069.20 EER28229.1 - 2.9e-42 144.6 0.0 1.1e-41 142.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER28229.1 - 1.2e-28 99.9 0.0 1.9e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER28229.1 - 2.9e-06 26.4 0.0 0.00026 20.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EER28229.1 - 0.025 13.6 0.0 0.12 11.4 0.0 2.0 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EER28229.1 - 0.18 10.5 0.0 0.46 9.2 0.0 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase NGP1NT PF08153.7 EER28230.1 - 1.7e-49 167.0 0.1 2.8e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EER28230.1 - 2.5e-19 69.3 0.1 1.2e-14 54.2 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EER28230.1 - 1.2e-05 24.6 0.0 0.00018 20.8 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EER28230.1 - 0.00038 20.3 0.1 0.16 11.7 0.1 3.5 2 1 0 2 2 2 1 Dynamin family Arf PF00025.16 EER28230.1 - 0.00059 19.1 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EER28230.1 - 0.0033 16.8 0.0 0.68 9.3 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EER28230.1 - 0.0034 16.5 0.0 0.0073 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SusD-like_3 PF14322.1 EER28230.1 - 0.045 13.8 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Starch-binding associating with outer membrane DEAD PF00270.24 EER28232.1 - 5.6e-43 146.3 0.0 7.6e-42 142.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER28232.1 - 6e-25 86.9 0.3 6e-25 86.9 0.2 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 EER28232.1 - 0.025 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) SNF2_N PF00176.18 EER28232.1 - 0.029 13.1 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EER28232.1 - 0.033 14.0 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2040 PF09745.4 EER28232.1 - 0.083 12.7 7.3 0.11 12.3 0.9 2.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) DUF2984 PF11203.3 EER28232.1 - 0.56 10.3 5.1 0.18 11.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2984) Suf PF05843.9 EER28233.1 - 0.0041 16.8 6.4 0.049 13.3 0.0 3.6 3 1 0 3 3 3 1 Suppressor of forked protein (Suf) FAT PF02259.18 EER28233.1 - 0.026 13.5 1.9 0.11 11.4 0.1 2.7 2 1 1 4 4 4 0 FAT domain TPR_14 PF13428.1 EER28233.1 - 0.069 13.8 3.3 9.9 7.1 0.0 5.4 7 2 2 9 9 9 0 Tetratricopeptide repeat MOSC_N PF03476.11 EER28235.1 - 1.1e-25 89.6 0.0 4.8e-25 87.6 0.0 2.0 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.14 EER28235.1 - 3.1e-22 78.8 0.0 9.6e-22 77.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 EER28235.1 - 1.7e-21 76.0 0.0 2.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MARVEL PF01284.18 EER28236.1 - 0.0052 16.6 13.9 0.007 16.1 9.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain Kei1 PF08552.6 EER28236.1 - 0.0072 16.0 0.1 0.011 15.4 0.1 1.5 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NMN_transporter PF04973.7 EER28236.1 - 0.011 15.2 2.3 0.94 8.9 0.0 2.1 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter DUF3413 PF11893.3 EER28236.1 - 0.013 14.3 4.6 0.11 11.3 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) HemY_N PF07219.8 EER28236.1 - 0.53 9.8 4.3 5.5 6.6 0.7 2.4 2 0 0 2 2 2 0 HemY protein N-terminus DUF3366 PF11846.3 EER28236.1 - 1.5 8.6 3.9 9.3 6.0 1.1 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3366) DUF4018 PF13210.1 EER28236.1 - 4.1 6.7 11.0 0.27 10.6 4.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) PAP2 PF01569.16 EER28237.1 - 4.9e-26 90.9 0.5 1.2e-25 89.6 0.3 1.6 1 0 0 1 1 1 1 PAP2 superfamily But2 PF09792.4 EER28238.1 - 7.4e-52 174.9 1.4 8.8e-52 174.6 1.0 1.0 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain bZIP_2 PF07716.10 EER28239.1 - 5.9e-05 22.8 8.6 8.5e-05 22.3 5.9 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EER28239.1 - 0.034 14.4 5.8 0.058 13.7 4.0 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_1 PF00170.16 EER28239.1 - 0.034 14.1 7.5 0.053 13.4 5.2 1.2 1 0 0 1 1 1 0 bZIP transcription factor Phage_Gp23 PF10669.4 EER28239.1 - 0.18 11.9 1.4 0.28 11.2 1.0 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) FB_lectin PF07367.6 EER28240.1 - 3.1e-09 36.5 0.0 3.1e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 Fungal fruit body lectin Sterol_MT_C PF08498.5 EER28241.1 - 3e-28 97.5 0.1 4.7e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EER28241.1 - 7.3e-16 58.4 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER28241.1 - 8.5e-15 54.6 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER28241.1 - 1.6e-13 50.6 0.0 2.6e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EER28241.1 - 6.9e-11 41.7 0.0 9.2e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EER28241.1 - 1.2e-10 41.6 0.0 2.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER28241.1 - 3.7e-10 40.3 0.0 8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER28241.1 - 1.1e-09 38.5 0.0 1.9e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EER28241.1 - 1e-07 31.3 0.0 1.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EER28241.1 - 2.3e-07 30.8 0.0 6.8e-07 29.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EER28241.1 - 0.00089 18.8 0.1 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EER28241.1 - 0.00096 18.5 0.0 0.0037 16.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.14 EER28241.1 - 0.0026 17.2 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EER28241.1 - 0.0046 16.1 0.0 0.0079 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EER28241.1 - 0.02 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EER28241.1 - 0.061 12.3 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 EER28241.1 - 0.092 13.5 0.0 0.34 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.13 EER28241.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 EER28241.1 - 0.15 11.0 0.0 0.38 9.7 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase RRM_5 PF13893.1 EER28242.1 - 4.5e-11 42.4 0.0 1.2e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER28242.1 - 4.6e-08 32.5 0.0 7.9e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER28242.1 - 3.1e-06 27.0 0.0 5.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER28242.1 - 0.079 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Complex1_LYR_1 PF13232.1 EER28243.1 - 0.00027 21.0 0.3 0.00053 20.1 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EER28243.1 - 0.00036 20.2 0.2 0.00061 19.5 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DnaJ PF00226.26 EER28244.1 - 3.9e-19 68.1 0.8 1.5e-18 66.3 0.5 2.1 1 0 0 1 1 1 1 DnaJ domain Sulfatase PF00884.18 EER28245.1 - 8.7e-58 195.9 0.1 1.1e-57 195.5 0.1 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EER28245.1 - 3.9e-21 74.6 0.5 8.6e-21 73.5 0.1 1.8 2 0 0 2 2 2 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EER28245.1 - 5.6e-09 35.7 0.2 3.6e-07 29.8 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EER28245.1 - 0.0045 17.2 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 EER28245.1 - 0.02 13.7 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.12 EER28245.1 - 0.048 12.0 0.0 0.069 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Amidohydro_1 PF01979.15 EER28246.1 - 5.3e-37 128.2 0.0 6.6e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EER28246.1 - 7.8e-09 35.2 0.9 1e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EER28246.1 - 0.00013 22.1 0.0 0.0042 17.1 0.0 2.6 1 1 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EER28246.1 - 0.002 17.0 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_5 PF13594.1 EER28246.1 - 0.013 15.3 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Amidohydrolase GDC-P PF02347.11 EER28247.1 - 5.3e-177 588.8 0.1 1.4e-162 541.2 0.0 3.3 3 1 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EER28247.1 - 3.6e-09 36.1 0.1 7.4e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EER28247.1 - 0.0026 16.8 0.0 0.0054 15.8 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family UBN2_3 PF14244.1 EER28248.1 - 0.0037 16.8 0.9 0.013 15.1 0.6 1.8 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EER28248.1 - 0.016 15.0 0.1 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pyridoxal_deC PF00282.14 EER28249.1 - 1.1e-110 369.5 0.0 1.3e-110 369.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain bZIP_2 PF07716.10 EER28250.1 - 8.2e-09 35.1 17.5 8.2e-09 35.1 12.2 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EER28250.1 - 1.9e-05 24.4 18.3 6e-05 22.9 12.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EER28250.1 - 0.00045 20.4 14.0 0.0012 19.0 9.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor CENP-Q PF13094.1 EER28250.1 - 0.06 13.3 10.1 0.11 12.5 7.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Caps_synth_GfcC PF06251.6 EER28250.1 - 0.081 12.0 4.5 0.69 9.0 2.2 2.1 2 0 0 2 2 2 0 Capsule biosynthesis GfcC APG6 PF04111.7 EER28250.1 - 0.12 11.3 9.9 0.19 10.7 6.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EER28250.1 - 0.25 10.5 7.3 0.41 9.7 5.1 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 NAM-associated PF14303.1 EER28250.1 - 0.26 11.6 11.0 0.44 10.8 7.7 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Striatin PF08232.7 EER28250.1 - 0.33 11.2 11.4 0.19 12.0 6.3 1.7 1 1 1 2 2 2 0 Striatin family DivIC PF04977.10 EER28250.1 - 7.1 6.1 9.9 1.4 8.4 0.9 2.5 1 1 1 2 2 2 0 Septum formation initiator Snf7 PF03357.16 EER28251.1 - 0.0012 18.3 9.6 0.0015 17.9 6.7 1.2 1 0 0 1 1 1 1 Snf7 Amidase PF01425.16 EER28253.1 - 1.6e-114 383.2 0.2 2.1e-114 382.8 0.1 1.1 1 0 0 1 1 1 1 Amidase SPRY PF00622.23 EER28254.1 - 0.0013 18.8 0.0 0.046 13.8 0.0 2.9 2 1 1 3 3 3 1 SPRY domain Bystin PF05291.6 EER28255.1 - 1.1e-125 418.5 0.0 1.8e-125 417.9 0.0 1.2 1 0 0 1 1 1 1 Bystin Actin PF00022.14 EER28256.1 - 2.2e-23 82.3 0.0 7.7e-23 80.5 0.0 1.8 2 1 0 2 2 2 1 Actin CBFD_NFYB_HMF PF00808.18 EER28257.1 - 1.2e-18 66.8 0.5 1.2e-18 66.8 0.3 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EER28257.1 - 0.00068 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EER28257.1 - 0.048 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.5 EER28257.1 - 0.2 11.5 3.9 0.11 12.3 1.3 1.6 2 0 0 2 2 2 0 YolD-like protein adh_short PF00106.20 EER28258.1 - 1.6e-26 93.2 0.2 2.2e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER28258.1 - 6.4e-15 55.5 0.0 1.1e-14 54.7 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER28258.1 - 2e-09 37.3 0.0 3e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EER28258.1 - 0.0017 18.4 0.0 0.0025 17.8 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EER28258.1 - 0.028 14.3 0.0 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Multi_Drug_Res PF00893.14 EER28258.1 - 0.053 13.9 0.3 0.083 13.3 0.2 1.3 1 0 0 1 1 1 0 Small Multidrug Resistance protein Glyco_tran_WecB PF03808.8 EER28258.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DAO PF01266.19 EER28259.1 - 2e-36 125.6 0.0 3e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EER28259.1 - 0.00033 21.0 0.0 0.016 15.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER28259.1 - 0.00051 20.0 0.0 0.0016 18.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER28259.1 - 0.00098 19.0 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER28259.1 - 0.039 13.7 0.2 0.097 12.4 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EER28259.1 - 0.11 12.5 0.0 1.2 9.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SMC_Nse1 PF07574.8 EER28260.1 - 3.8e-45 153.9 0.1 4.5e-45 153.7 0.1 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex DUF972 PF06156.8 EER28260.1 - 0.037 14.3 0.1 0.079 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Mrr_N PF14338.1 EER28260.1 - 0.074 13.1 0.1 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Mrr N-terminal domain DUF2161 PF09929.4 EER28260.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Glyco_hydro_65m PF03632.10 EER28261.1 - 3.3e-83 279.4 0.7 1.9e-82 276.9 0.1 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EER28261.1 - 5.4e-46 156.9 0.0 8.4e-46 156.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EER28261.1 - 4.9e-05 23.3 0.2 0.00011 22.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Beta-lactamase PF00144.19 EER28262.1 - 1e-33 116.8 0.0 1.6e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EER28262.1 - 0.0017 17.6 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 2 D-alanyl-D-alanine carboxypeptidase ADH_zinc_N PF00107.21 EER28263.1 - 2e-14 53.2 0.0 4.1e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase KR PF08659.5 EER28263.1 - 0.00034 20.3 0.3 0.00055 19.6 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EER28263.1 - 0.0014 18.5 0.2 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase ADH_N PF08240.7 EER28263.1 - 0.0022 17.7 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 EER28263.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF4265 PF14085.1 EER28263.1 - 0.025 14.3 0.0 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) AAA_30 PF13604.1 EER28263.1 - 0.11 12.0 0.2 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain Metallophos PF00149.23 EER28264.1 - 7.3e-08 32.0 2.1 1.3e-07 31.2 1.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.13 EER28264.1 - 0.013 15.5 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.19 EER28265.1 - 2.5e-46 157.3 0.0 3.9e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EER28265.1 - 2e-33 114.9 0.1 6.3e-33 113.3 0.0 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain zf-C2H2 PF00096.21 EER28266.1 - 0.0021 18.2 1.8 0.0044 17.2 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EER28266.1 - 0.0032 17.5 4.3 0.0049 16.9 3.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EER28266.1 - 0.0049 17.0 0.7 0.0081 16.3 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EER28266.1 - 0.011 15.9 0.6 0.025 14.8 0.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EER28266.1 - 0.033 14.1 0.5 0.033 14.1 0.3 1.5 1 1 0 1 1 1 0 C2H2-type zinc finger UPF0240 PF06784.6 EER28266.1 - 0.068 12.8 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) zf-C2H2_2 PF12756.2 EER28266.1 - 0.074 13.1 0.3 0.11 12.6 0.2 1.1 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) GRP PF07172.6 EER28266.1 - 0.38 11.2 18.4 0.17 12.3 7.7 2.2 2 0 0 2 2 2 0 Glycine rich protein family DUF1691 PF07950.6 EER28267.1 - 3.1e-47 159.0 4.9 1.3e-30 105.5 2.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) APH PF01636.18 EER28268.1 - 0.00016 21.4 0.0 0.00074 19.3 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Membrane_bind PF14564.1 EER28269.1 - 2.7e-33 114.4 0.0 4.4e-33 113.7 0.0 1.3 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.5 EER28269.1 - 0.00012 21.6 0.1 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 Beta/Gamma crystallin TRM PF02005.11 EER28270.1 - 2.7e-110 368.8 0.0 4.7e-95 318.6 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EER28270.1 - 0.00021 20.9 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EER28270.1 - 0.0044 17.5 0.0 0.0095 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF2067 PF09840.4 EER28270.1 - 0.033 13.6 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Methyltransf_26 PF13659.1 EER28270.1 - 0.036 14.1 0.0 0.084 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EER28270.1 - 0.067 12.5 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Iso_dh PF00180.15 EER28271.1 - 3.6e-109 364.9 0.0 4.2e-109 364.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ketoacyl-synt PF00109.21 EER28272.1 - 1.8e-18 66.9 0.0 3.7e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EER28272.1 - 2.8e-18 65.7 0.0 5.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EER28272.1 - 6.5e-11 42.1 0.0 2.3e-10 40.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EER28272.1 - 8.2e-07 29.0 0.0 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER28272.1 - 0.00097 18.8 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EER28272.1 - 0.071 13.5 1.0 0.2 12.1 0.1 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Acyl_transf_1 PF00698.16 EER28273.1 - 3.4e-86 289.4 0.0 4.6e-83 279.1 0.0 3.0 2 0 0 2 2 2 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EER28273.1 - 9.2e-40 134.8 0.2 2.8e-39 133.2 0.0 1.9 2 0 0 2 2 2 1 MaoC like domain DUF1729 PF08354.5 EER28273.1 - 8.4e-33 111.9 1.4 5.2e-32 109.4 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EER28273.1 - 1.7e-19 69.9 0.0 6.2e-19 68.0 0.0 2.0 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase MCRS_N PF13325.1 EER28273.1 - 0.076 12.5 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of micro-spherule protein DeoC PF01791.4 EER28273.1 - 0.1 11.8 0.4 10 5.2 0.0 2.7 3 0 0 3 3 3 0 DeoC/LacD family aldolase Phi-29_GP3 PF05435.6 EER28273.1 - 0.17 11.0 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 TFIIF_alpha PF05793.7 EER28274.1 - 2.8e-11 42.4 52.8 2.8e-11 42.4 36.6 3.5 2 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PAP_assoc PF03828.14 EER28275.1 - 3.3e-17 62.1 0.3 9.2e-17 60.7 0.2 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase PAP_central PF04928.12 EER28275.1 - 0.0019 17.0 0.3 0.0082 14.9 0.1 2.0 2 0 0 2 2 2 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.18 EER28275.1 - 0.078 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain Rep-A_N PF04057.7 EER28276.1 - 0.002 17.8 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF383 PF04063.9 EER28277.1 - 4.9e-72 241.5 0.3 2.6e-71 239.1 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EER28277.1 - 2.5e-23 81.3 0.1 7.7e-23 79.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) RICTOR_M PF14666.1 EER28277.1 - 0.07 12.1 0.0 2 7.3 0.0 2.4 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain Methyltransf_23 PF13489.1 EER28278.1 - 2.4e-09 37.1 0.0 4.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER28278.1 - 0.0016 18.8 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER28278.1 - 0.0029 18.0 0.0 0.0091 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER28278.1 - 0.003 17.1 0.0 0.0084 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER28278.1 - 0.017 15.4 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Inositol_P PF00459.20 EER28279.1 - 8e-69 231.9 0.0 8.9e-69 231.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family IBR PF01485.16 EER28280.1 - 3.3e-12 46.0 48.6 2.4e-07 30.5 8.2 3.7 3 1 0 3 3 3 2 IBR domain DUF605 PF04652.11 EER28280.1 - 0.036 13.4 21.5 0.066 12.5 9.6 2.1 2 0 0 2 2 2 0 Vta1 like DUF936 PF06075.7 EER28280.1 - 1.5 7.6 21.2 2.4 6.9 14.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF676 PF05057.9 EER28281.1 - 1.7e-40 138.6 0.0 5.8e-27 94.4 0.0 3.2 2 1 0 2 2 2 2 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EER28281.1 - 0.024 14.2 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 EER28281.1 - 0.074 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EER28281.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DAGK_cat PF00781.19 EER28283.1 - 3.1e-09 36.3 0.0 7.8e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain His_Phos_2 PF00328.17 EER28284.1 - 2e-119 398.9 0.0 2.6e-119 398.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EER28284.1 - 1.5e-07 31.1 0.0 3.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EER28285.1 - 1.4e-85 286.1 0.1 2.1e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EER28285.1 - 1.7e-22 78.4 24.1 4.8e-05 23.0 0.5 9.6 10 0 0 10 10 10 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EER28285.1 - 0.13 10.4 0.0 0.31 9.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain eIF2A PF08662.6 EER28285.1 - 0.19 11.3 0.3 0.85 9.2 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PsbN PF02468.10 EER28286.1 - 0.41 10.2 3.3 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Photosystem II reaction centre N protein (psbN) RCR PF12273.3 EER28286.1 - 1.1 9.7 5.8 4.6 7.8 4.0 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red XPG_I_2 PF12813.2 EER28287.1 - 2e-83 279.6 0.0 3e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EER28287.1 - 0.0011 19.0 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc_N PF02739.11 EER28287.1 - 0.019 14.3 0.0 0.071 12.4 0.0 1.8 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain adh_short_C2 PF13561.1 EER28288.1 - 1.1e-27 97.4 0.0 1.3e-27 97.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER28288.1 - 7.5e-19 68.2 2.5 1e-18 67.8 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.13 EER28288.1 - 0.013 15.1 0.4 0.025 14.2 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NanE PF04131.9 EER28288.1 - 0.045 12.7 0.1 0.084 11.8 0.1 1.3 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Methyltransf_18 PF12847.2 EER28288.1 - 0.097 13.2 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain HET PF06985.6 EER28290.1 - 1.6e-33 115.8 0.1 6.6e-33 113.8 0.1 2.1 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Fcf1 PF04900.7 EER28291.1 - 3.8e-41 139.2 1.3 6.5e-41 138.5 0.5 1.7 2 0 0 2 2 2 1 Fcf1 Exostosin PF03016.10 EER28291.1 - 0.039 12.9 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Exostosin family Fringe PF02434.11 EER28292.1 - 1.5e-06 27.6 0.2 4e-05 22.9 0.1 2.4 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 EER28292.1 - 0.0032 17.1 2.0 0.006 16.3 1.4 1.4 1 0 0 1 1 1 1 PAN domain DUF604 PF04646.7 EER28292.1 - 0.0079 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_2 PF08276.6 EER28292.1 - 0.012 15.4 0.3 0.022 14.5 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.1 EER28292.1 - 0.11 12.1 1.5 0.25 11.0 1.0 1.5 1 0 0 1 1 1 0 PAN domain Glyco_transf_34 PF05637.7 EER28292.1 - 0.25 10.7 4.5 0.22 10.9 1.7 1.7 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family GFA PF04828.9 EER28293.1 - 1.7e-12 47.0 0.9 3.1e-08 33.4 0.1 2.2 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 EER28293.1 - 0.062 13.1 0.2 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 EER28293.1 - 1.3 8.7 5.2 0.62 9.7 0.1 2.7 3 0 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.6 EER28293.1 - 6.7 6.3 8.1 0.83 9.2 0.6 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain RVT_2 PF07727.9 EER28295.1 - 1.1e-68 230.8 0.0 3.5e-68 229.2 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EER28295.1 - 3.6e-19 69.0 0.0 1.9e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EER28295.1 - 3.1e-06 26.7 0.1 7.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EER28295.1 - 1.2e-05 25.0 2.3 2.3e-05 24.0 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Phage_Gp23 PF10669.4 EER28295.1 - 0.79 9.8 10.1 0.062 13.4 2.0 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Ras PF00071.17 EER28296.1 - 5.3e-65 217.7 0.0 6.7e-65 217.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER28296.1 - 5.7e-18 65.5 0.0 1.7e-17 63.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EER28296.1 - 3.7e-13 49.0 0.0 4.7e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER28296.1 - 5.5e-06 25.6 0.0 6.8e-06 25.3 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EER28296.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EER28296.1 - 0.0091 15.9 0.0 0.015 15.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF2589 PF11655.3 EER28296.1 - 0.036 14.2 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2589) DUF258 PF03193.11 EER28296.1 - 0.066 12.3 0.1 0.22 10.7 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EER28296.1 - 0.067 12.4 0.0 0.23 10.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EER28296.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NCA2 PF08637.5 EER28297.1 - 1e-83 280.6 0.0 1.6e-83 279.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 EER28298.1 - 2.2e-15 57.0 18.3 2.2e-15 57.0 12.7 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Pterin_4a PF01329.14 EER28299.1 - 2.2e-29 101.0 0.0 2.9e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase AAA PF00004.24 EER28300.1 - 1.9e-61 206.0 0.0 1.1e-41 142.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER28300.1 - 2.4e-10 40.7 2.7 0.00067 19.6 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EER28300.1 - 1.4e-07 31.6 6.0 0.81 9.8 0.4 5.0 2 2 3 5 5 5 3 AAA domain AAA_5 PF07728.9 EER28300.1 - 6.4e-07 29.1 0.8 0.0039 16.9 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EER28300.1 - 9.3e-06 25.6 0.0 0.031 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 EER28300.1 - 2.4e-05 24.0 0.0 0.00016 21.3 0.0 2.1 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_17 PF13207.1 EER28300.1 - 5.9e-05 23.8 0.0 0.64 10.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EER28300.1 - 6e-05 22.7 0.8 0.34 10.6 0.0 3.6 4 0 0 4 4 3 2 Part of AAA domain AAA_25 PF13481.1 EER28300.1 - 0.00011 21.6 6.8 0.31 10.4 0.0 4.0 2 2 2 4 4 4 1 AAA domain AAA_14 PF13173.1 EER28300.1 - 0.00016 21.5 0.0 0.1 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EER28300.1 - 0.00031 20.5 0.1 0.15 11.7 0.1 3.0 2 2 1 3 3 3 1 Archaeal ATPase TIP49 PF06068.8 EER28300.1 - 0.00042 19.1 0.3 0.0054 15.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus NACHT PF05729.7 EER28300.1 - 0.0016 18.1 1.9 1.2 8.7 0.2 3.8 2 2 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EER28300.1 - 0.002 18.3 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 EER28300.1 - 0.0024 16.9 0.0 0.1 11.6 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EER28300.1 - 0.0025 16.7 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EER28300.1 - 0.0051 16.2 0.0 3.1 7.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_2 PF07724.9 EER28300.1 - 0.0065 16.4 0.0 0.044 13.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.10 EER28300.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EER28300.1 - 0.013 15.0 4.4 0.1 12.1 0.4 2.5 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EER28300.1 - 0.014 14.6 0.4 0.3 10.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EER28300.1 - 0.022 15.1 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EER28300.1 - 0.029 13.9 0.0 8.5 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain CDC48_N PF02359.13 EER28300.1 - 0.029 14.2 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activ_2 PF14532.1 EER28300.1 - 0.032 14.2 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain MobB PF03205.9 EER28300.1 - 0.05 13.3 0.0 0.58 9.8 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Vps4_C PF09336.5 EER28300.1 - 0.1 12.4 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Miro PF08477.8 EER28300.1 - 0.1 13.0 0.2 0.36 11.3 0.1 2.0 2 0 0 2 2 1 0 Miro-like protein PI3_PI4_kinase PF00454.22 EER28301.1 - 3e-47 161.0 0.0 6.3e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EER28301.1 - 2.3e-45 155.0 3.8 2.5e-45 154.9 1.6 1.9 2 0 0 2 2 2 1 FAT domain UME PF08064.8 EER28301.1 - 2.5e-34 117.4 1.0 2.5e-34 117.4 0.7 2.6 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EER28301.1 - 5.5e-16 57.6 0.0 1.2e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 FATC domain TPR_14 PF13428.1 EER28301.1 - 0.0038 17.7 5.0 1.6 9.6 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EER28301.1 - 0.017 14.7 4.0 7.9 6.2 0.0 4.0 4 0 0 4 4 4 0 TPR repeat DUF3385 PF11865.3 EER28301.1 - 0.025 14.4 0.0 0.61 9.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) TPR_16 PF13432.1 EER28301.1 - 0.1 13.3 0.2 1.6 9.4 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat dCMP_cyt_deam_1 PF00383.17 EER28302.1 - 4.1e-25 87.3 0.0 5.4e-25 87.0 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EER28302.1 - 0.0038 17.0 0.3 0.024 14.5 0.2 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase NADH-u_ox-rdase PF10785.4 EER28303.1 - 1.6e-35 121.1 0.1 2.7e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EER28303.1 - 2.7e-35 119.9 0.2 3.8e-35 119.4 0.2 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Swi3 PF07962.7 EER28304.1 - 9.6e-32 108.4 0.4 2.3e-31 107.2 0.3 1.7 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RCC1 PF00415.13 EER28305.1 - 5.4e-61 202.6 5.4 3.9e-13 49.3 0.0 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EER28305.1 - 6.4e-40 133.9 28.4 7.9e-09 34.9 0.1 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Cyclase PF04199.8 EER28306.1 - 4.9e-11 42.6 0.0 6.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase DUF4132 PF13569.1 EER28306.1 - 0.068 12.6 0.2 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4132) RibD_C PF01872.12 EER28307.1 - 3.4e-31 108.4 0.0 7.3e-31 107.3 0.0 1.6 1 0 0 1 1 1 1 RibD C-terminal domain FAR1 PF03101.10 EER28307.1 - 0.34 11.4 2.3 0.76 10.3 1.6 1.6 1 0 0 1 1 1 0 FAR1 DNA-binding domain Nic96 PF04097.9 EER28308.1 - 1.3e-210 700.7 0.2 1.5e-210 700.4 0.2 1.1 1 0 0 1 1 1 1 Nup93/Nic96 COX16 PF14138.1 EER28309.1 - 1.3e-21 76.5 0.0 1.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Y_phosphatase PF00102.22 EER28310.1 - 2.2e-61 207.1 0.0 3.3e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EER28310.1 - 3.3e-11 43.5 0.0 4e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 EER28310.1 - 0.02 14.5 0.1 0.041 13.4 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EER28310.1 - 0.21 11.7 0.0 0.43 10.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box-like_2 PF13013.1 EER28311.1 - 5.6e-07 29.2 0.2 1.3e-06 28.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 EER28311.1 - 4.8e-06 26.0 0.8 1.2e-05 24.8 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER28311.1 - 0.0007 19.2 1.1 0.0016 18.1 0.7 1.6 1 0 0 1 1 1 1 F-box-like Dynamin_N PF00350.18 EER28312.1 - 1.3e-33 116.2 0.1 2.4e-33 115.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EER28312.1 - 2.2e-17 62.7 0.0 1.9e-16 59.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 EER28312.1 - 8.1e-05 22.5 0.0 0.00026 20.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER28312.1 - 0.0047 17.4 0.3 0.027 14.9 0.2 2.3 1 1 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 EER28312.1 - 0.0086 16.0 0.0 0.028 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2478 PF10649.4 EER28312.1 - 0.0088 15.3 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2478) FGGY_C PF02782.11 EER28314.1 - 4.6e-53 179.7 0.1 7.4e-53 179.1 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EER28314.1 - 5.2e-24 84.9 0.0 3.5e-21 75.6 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EER28314.1 - 0.056 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Na_Ca_ex PF01699.19 EER28315.1 - 4.1e-30 104.2 30.3 6.2e-18 64.7 6.4 3.3 4 1 1 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EER28315.1 - 5.4e-13 49.1 13.7 5.4e-13 49.1 9.5 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF307) eIF-3c_N PF05470.7 EER28315.1 - 0.32 9.0 0.0 0.44 8.5 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AAA PF00004.24 EER28316.1 - 5.2e-44 149.6 0.0 8.5e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EER28316.1 - 3.2e-08 33.4 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EER28316.1 - 1.2e-07 31.7 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EER28316.1 - 3.1e-06 27.3 0.0 6.8e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EER28316.1 - 4.8e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EER28316.1 - 6.6e-05 23.7 0.0 0.00015 22.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EER28316.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EER28316.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EER28316.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EER28316.1 - 0.00086 18.1 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EER28316.1 - 0.0014 18.4 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EER28316.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EER28316.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EER28316.1 - 0.0025 17.4 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EER28316.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EER28316.1 - 0.0058 16.9 0.0 0.028 14.7 0.0 2.3 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EER28316.1 - 0.0066 15.6 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EER28316.1 - 0.0073 15.4 0.0 0.017 14.2 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EER28316.1 - 0.018 14.4 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.8 EER28316.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EER28316.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.11 EER28316.1 - 0.02 14.1 0.0 0.07 12.3 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 EER28316.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EER28316.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EER28316.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EER28316.1 - 0.052 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.4 EER28316.1 - 0.055 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NB-ARC PF00931.17 EER28316.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EER28316.1 - 0.099 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EER28316.1 - 0.1 12.2 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain FlhC PF05280.6 EER28317.1 - 1.1 8.6 4.3 2.7 7.4 3.0 1.6 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) UFD1 PF03152.9 EER28318.1 - 5.6e-28 97.2 0.0 1.7e-23 82.6 0.0 3.0 1 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 Cytochrome_C554 PF13435.1 EER28318.1 - 8.1 6.5 23.3 6.8 6.7 10.6 2.4 1 1 1 2 2 2 0 Cytochrome c554 and c-prime Yip1 PF04893.12 EER28319.1 - 8.9e-06 25.3 15.4 8.9e-06 25.3 10.7 2.6 2 1 0 2 2 2 1 Yip1 domain Bac_surface_Ag PF01103.18 EER28320.1 - 1.3e-43 149.7 0.0 1.6e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Surface antigen YopJ PF03421.11 EER28320.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 YopJ Serine/Threonine acetyltransferase UQ_con PF00179.21 EER28321.1 - 2.1e-26 92.0 0.1 3e-26 91.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Fungal_trans_2 PF11951.3 EER28322.1 - 6.9e-11 41.3 0.0 3.3e-06 25.9 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain Cyto_heme_lyase PF01265.12 EER28323.1 - 1.1e-80 270.9 0.1 1.3e-80 270.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Abhydrolase_6 PF12697.2 EER28324.1 - 0.00046 20.1 0.0 0.00081 19.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EER28324.1 - 0.00077 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Lipase_3 PF01764.20 EER28324.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.9 EER28324.1 - 0.012 14.9 0.1 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EER28324.1 - 0.022 14.5 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EER28324.1 - 0.065 12.8 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein HA2 PF04408.18 EER28325.1 - 3.2e-11 43.1 0.0 2.7e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EER28325.1 - 0.009 15.8 0.0 0.026 14.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 EER28325.1 - 0.096 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC1 PF03109.11 EER28326.1 - 3.1e-23 82.0 0.0 2.3e-14 53.3 0.0 2.5 1 1 0 2 2 2 2 ABC1 family RIO1 PF01163.17 EER28326.1 - 0.078 12.3 0.0 0.75 9.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family DAO PF01266.19 EER28327.1 - 2.4e-27 95.8 0.1 2.9e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER28327.1 - 1.2e-06 28.4 0.0 3.2e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EER28327.1 - 3.1e-05 24.3 0.7 0.00053 20.3 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EER28327.1 - 0.00012 21.2 0.0 0.00031 19.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EER28327.1 - 0.00038 19.4 0.1 0.0017 17.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EER28327.1 - 0.00041 20.3 0.0 0.024 14.5 0.0 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EER28327.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EER28327.1 - 0.0093 16.0 0.2 0.71 9.8 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EER28327.1 - 0.027 14.4 0.4 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 NADH(P)-binding GIDA PF01134.17 EER28327.1 - 0.054 12.3 0.0 0.099 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EER28327.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EER28327.1 - 0.11 12.5 0.1 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SLIDE PF09111.5 EER28327.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 SLIDE MFS_1 PF07690.11 EER28328.1 - 2.8e-43 147.9 39.6 2.8e-43 147.9 27.4 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER28328.1 - 2.8e-14 52.5 29.8 9.6e-14 50.7 3.2 3.3 3 1 0 4 4 4 2 Sugar (and other) transporter Pox_A14 PF05767.7 EER28328.1 - 0.034 14.1 0.4 1.1 9.3 0.0 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Pro_CA PF00484.14 EER28329.1 - 2.3e-27 95.8 0.0 2.9e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase SLAC1 PF03595.12 EER28330.1 - 9.4e-74 247.9 55.0 1.1e-73 247.7 38.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel adh_short PF00106.20 EER28331.1 - 2e-21 76.6 0.1 3.1e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER28331.1 - 1.2e-12 48.1 0.0 1.6e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EER28331.1 - 8e-05 21.9 0.0 0.0067 15.5 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) KR PF08659.5 EER28331.1 - 0.0019 17.9 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EER28331.1 - 0.0092 16.0 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EER28331.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family PAE PF03283.8 EER28331.1 - 0.09 11.3 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase ATP-grasp_2 PF08442.5 EER28332.1 - 7.6e-79 263.7 0.6 1.4e-78 262.9 0.4 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EER28332.1 - 3.6e-25 88.3 0.2 6.8e-25 87.4 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EER28332.1 - 8.8e-11 41.4 1.1 1.3e-10 40.9 0.1 1.7 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EER28332.1 - 0.0027 17.3 0.3 0.059 12.9 0.0 2.4 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EER28332.1 - 0.04 13.3 0.0 0.4 10.1 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.12 EER28332.1 - 0.048 12.9 0.1 0.12 11.6 0.1 1.7 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 EER28332.1 - 0.075 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EER28332.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain DUF3245 PF11595.3 EER28333.1 - 6.6e-38 130.3 6.8 1.3e-37 129.4 4.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) HSF_DNA-bind PF00447.12 EER28334.1 - 2.9e-36 123.7 0.4 4.4e-36 123.1 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding F-box-like PF12937.2 EER28335.1 - 9e-06 25.3 0.1 2.4e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER28335.1 - 0.00011 21.7 2.3 0.00014 21.4 0.0 2.4 2 0 0 2 2 2 1 F-box domain DUF872 PF05915.7 EER28336.1 - 0.23 11.3 1.5 0.41 10.5 1.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF3902 PF13042.1 EER28337.1 - 0.058 12.6 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Radical_SAM PF04055.16 EER28338.1 - 4.2e-05 23.7 0.0 0.00017 21.7 0.0 2.0 2 1 0 2 2 2 1 Radical SAM superfamily Pkinase PF00069.20 EER28340.1 - 1.3e-08 34.2 0.0 1.6e-08 34.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pribosyltran PF00156.22 EER28341.1 - 1.8e-06 27.6 0.2 7.3e-06 25.7 0.2 1.9 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.6 EER28342.1 - 1.1e-28 98.8 0.5 1.2e-28 98.7 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Abhydrolase_6 PF12697.2 EER28343.1 - 3.9e-28 98.8 0.0 1.1e-27 97.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER28343.1 - 2.3e-14 53.5 0.0 8.5e-10 38.5 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER28343.1 - 3.6e-12 46.2 0.0 6.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EER28343.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.8 1 1 1 2 2 2 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EER28343.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EER28343.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EER28343.1 - 0.11 12.7 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 Thioesterase domain Zn_clus PF00172.13 EER28344.1 - 1.7e-06 27.8 9.1 3.3e-06 26.8 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FSH1 PF03959.8 EER28345.1 - 3e-26 92.2 0.0 5e-17 62.0 0.0 2.7 2 1 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EER28345.1 - 3.7e-06 27.0 0.0 4.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Methyltransf_2 PF00891.13 EER28346.1 - 3.4e-26 91.9 0.0 4.4e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase AflR PF08493.5 EER28347.1 - 2.9e-09 36.3 0.0 2.9e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EER28347.1 - 1e-06 28.5 8.6 1.9e-06 27.6 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EER28348.1 - 1.3e-39 135.9 50.1 5.2e-39 133.9 34.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2909 PF11137.3 EER28348.1 - 0.15 11.7 8.6 3.3 7.5 0.5 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2909) ketoacyl-synt PF00109.21 EER28349.1 - 5e-21 75.3 0.0 1.7e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EER28349.1 - 2.3e-18 66.8 0.0 4.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EER28349.1 - 1.2e-15 57.3 0.0 5.2e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 EER28349.1 - 4.5e-15 55.4 0.0 1e-14 54.3 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 EER28349.1 - 0.0024 17.7 0.0 0.0082 16.0 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Thiolase_N PF00108.18 EER28349.1 - 0.05 12.5 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain DUF4463 PF14703.1 EER28349.1 - 0.28 11.7 0.0 0.75 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Acyl_transf_1 PF00698.16 EER28350.1 - 3.7e-63 213.7 2.5 3.3e-60 204.0 0.0 3.5 3 1 0 3 3 3 2 Acyl transferase domain DUF1729 PF08354.5 EER28350.1 - 1.3e-28 98.5 0.0 2.8e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EER28350.1 - 9.9e-26 89.5 0.0 2.4e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EER28350.1 - 4e-11 42.8 0.0 2.1e-10 40.4 0.0 2.3 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EER28350.1 - 0.0027 16.9 0.1 0.077 12.1 0.1 2.4 1 1 0 1 1 1 1 Nitronate monooxygenase ketoacyl-synt PF00109.21 EER28351.1 - 1.1e-79 267.5 0.0 2.5e-79 266.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EER28351.1 - 1.1e-49 169.5 0.1 3.3e-49 167.9 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EER28351.1 - 1.2e-33 115.4 0.1 2.6e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EER28351.1 - 5.2e-32 111.9 0.0 1.7e-31 110.2 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EER28351.1 - 5.3e-23 81.0 6.6 1.2e-11 44.6 0.3 3.5 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 EER28351.1 - 3.7e-09 36.1 0.0 6.3e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 EER28351.1 - 3.2e-07 30.1 0.1 0.069 12.9 0.0 3.3 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER28351.1 - 1.3e-05 25.2 3.1 0.0062 16.4 0.0 3.9 4 0 0 4 4 4 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EER28351.1 - 0.00056 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ZapA PF05164.8 EER28351.1 - 0.39 10.7 0.0 0.91 9.5 0.0 1.6 1 0 0 1 1 1 0 Cell division protein ZapA Stathmin PF00836.14 EER28351.1 - 0.46 10.1 0.0 0.98 9.0 0.0 1.4 1 0 0 1 1 1 0 Stathmin family Peptidase_M35 PF02102.10 EER28352.1 - 1e-104 350.0 0.0 1.2e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EER28352.1 - 0.0001 22.8 0.1 0.00018 22.0 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Myb_DNA-binding PF00249.26 EER28352.1 - 0.042 13.9 0.0 0.17 11.9 0.0 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain KAP PF05804.7 EER28353.1 - 2.1e-07 29.3 0.1 2.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Arm PF00514.18 EER28353.1 - 0.00098 18.8 3.5 1.9 8.4 0.1 4.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Mac PF12464.3 EER28353.1 - 0.49 10.4 1.8 1.1 9.3 0.1 2.4 3 0 0 3 3 3 0 Maltose acetyltransferase Oxidored-like PF09791.4 EER28354.1 - 4.2e-26 90.1 4.3 4.2e-26 90.1 3.0 2.1 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DUF1488 PF07369.6 EER28354.1 - 0.11 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) Ribosomal_L13e PF01294.13 EER28356.1 - 7.2e-66 221.0 4.2 1.1e-65 220.5 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e GvpK PF05121.7 EER28357.1 - 0.01 15.6 0.6 0.03 14.1 0.4 1.7 1 0 0 1 1 1 0 Gas vesicle protein K CENP-F_leu_zip PF10473.4 EER28357.1 - 0.049 13.4 5.7 0.088 12.6 4.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EER28357.1 - 0.24 10.9 5.5 0.53 9.8 3.8 1.6 1 0 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 EER28357.1 - 0.35 10.5 7.2 0.67 9.6 5.0 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding LRR_4 PF12799.2 EER28358.1 - 3.9e-31 106.1 44.7 1.3e-08 34.2 0.5 10.7 4 2 8 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER28358.1 - 4.6e-31 106.3 38.5 1.1e-08 34.7 0.9 8.4 5 2 3 8 8 8 8 Leucine rich repeat LRR_7 PF13504.1 EER28358.1 - 3e-17 59.6 35.3 0.86 10.0 0.0 14.9 16 0 0 16 16 16 6 Leucine rich repeat LRR_1 PF00560.28 EER28358.1 - 3.1e-15 53.8 48.1 0.081 13.0 0.1 15.3 15 2 0 15 15 15 6 Leucine Rich Repeat LRR_6 PF13516.1 EER28358.1 - 1.7e-08 33.6 29.9 2.6 8.3 0.0 12.5 12 2 2 14 14 14 4 Leucine Rich repeat LRR_9 PF14580.1 EER28358.1 - 0.0046 16.5 8.9 0.43 10.1 0.1 3.7 3 1 0 3 3 3 2 Leucine-rich repeat GCIP PF13324.1 EER28359.1 - 1.1e-07 31.4 0.3 7.8e-06 25.3 0.1 2.2 1 1 1 2 2 2 2 Grap2 and cyclin-D-interacting DUF722 PF05263.6 EER28359.1 - 0.091 12.8 0.7 0.17 11.9 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Actin PF00022.14 EER28360.1 - 1.5e-100 336.3 0.0 1.8e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Actin IBR PF01485.16 EER28361.1 - 1.9e-09 37.2 34.4 6.7e-05 22.6 9.9 3.5 3 0 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EER28361.1 - 0.00054 19.7 7.7 0.00054 19.7 5.3 4.4 2 1 2 4 4 4 1 Ring finger domain UPF0547 PF10571.4 EER28361.1 - 2.9 7.6 15.7 0.051 13.2 2.3 3.4 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 3HCDH_N PF02737.13 EER28362.1 - 8.4e-54 181.9 2.4 1.1e-53 181.5 1.6 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EER28362.1 - 2.3e-35 120.8 0.0 5.3e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ApbA PF02558.11 EER28362.1 - 3e-06 26.7 0.2 0.00014 21.2 0.1 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EER28362.1 - 4.7e-06 26.4 0.4 6.7e-06 25.9 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EER28362.1 - 4.9e-06 26.4 0.4 1.3e-05 25.1 0.3 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 EER28362.1 - 0.00021 20.3 0.5 0.0004 19.3 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EER28362.1 - 0.00034 20.0 0.5 0.0012 18.2 0.3 1.9 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 EER28362.1 - 0.0012 18.7 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER28362.1 - 0.0014 18.9 0.3 0.0031 17.8 0.1 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 EER28362.1 - 0.0056 15.7 0.1 0.0064 15.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EER28362.1 - 0.016 15.2 0.1 0.038 13.9 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EER28362.1 - 0.036 14.4 2.5 0.075 13.4 0.6 2.2 1 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent HI0933_like PF03486.9 EER28362.1 - 0.041 12.3 0.7 0.069 11.5 0.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EER28362.1 - 0.045 13.7 1.5 0.19 11.7 0.8 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EER28362.1 - 0.058 12.9 0.2 0.092 12.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EER28362.1 - 0.071 13.3 0.3 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 EER28362.1 - 0.097 11.8 0.5 0.27 10.3 0.1 1.8 1 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TIMELESS PF04821.9 EER28363.1 - 1.2e-92 309.9 0.0 2.2e-92 309.0 0.0 1.5 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 EER28363.1 - 1e-44 153.4 7.5 2.9e-43 148.6 2.2 3.3 1 1 1 2 2 2 1 Timeless protein C terminal region PhzC-PhzF PF02567.11 EER28364.1 - 7e-48 163.2 0.1 2.9e-47 161.2 0.0 1.8 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Tfb2 PF03849.9 EER28366.1 - 1.1e-142 475.1 0.0 2.1e-142 474.1 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EER28366.1 - 1.1e-06 28.3 0.0 5.8e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SinI PF08671.5 EER28366.1 - 0.089 12.2 0.0 0.24 10.8 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI 4HBT PF03061.17 EER28367.1 - 1.5e-13 50.6 0.1 2.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EER28367.1 - 0.0056 16.4 0.0 0.0063 16.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily PI-PLC-X PF00388.14 EER28367.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.3 1 1 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain AAA_12 PF13087.1 EER28368.1 - 4.7e-27 94.6 0.0 9.3e-27 93.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EER28368.1 - 2e-23 83.1 0.0 3.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER28368.1 - 1.2e-09 37.8 0.2 7.1e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EER28368.1 - 1.2e-05 25.0 0.0 0.0028 17.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EER28368.1 - 0.00037 20.3 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EER28368.1 - 0.0004 19.8 0.0 0.0009 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EER28368.1 - 0.0049 17.0 0.0 0.012 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EER28368.1 - 0.0055 16.2 0.1 0.3 10.5 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EER28368.1 - 0.0056 16.6 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EER28368.1 - 0.0077 15.2 0.2 0.019 13.9 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EER28368.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EER28368.1 - 0.021 14.3 0.1 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_17 PF13207.1 EER28368.1 - 0.023 15.5 0.0 0.47 11.2 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EER28368.1 - 0.024 14.3 0.0 0.058 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.16 EER28368.1 - 0.041 13.1 0.0 0.14 11.4 0.0 1.9 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Zeta_toxin PF06414.7 EER28368.1 - 0.053 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.9 EER28368.1 - 0.063 12.2 0.0 9.7 5.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase DnaB_C PF03796.10 EER28368.1 - 0.089 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NB-ARC PF00931.17 EER28368.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EER28368.1 - 0.21 11.7 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 1 0 RNA helicase Parvo_NS1 PF01057.12 EER28368.1 - 0.28 10.0 0.0 0.5 9.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 efThoc1 PF11957.3 EER28369.1 - 9.1e-171 568.6 1.6 1.2e-170 568.2 1.1 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor HCMVantigenic_N PF12154.3 EER28369.1 - 0.043 13.7 1.3 0.086 12.7 0.9 1.5 1 0 0 1 1 1 0 Glycoprotein B N-terminal antigenic domain of HCMV Homeobox PF00046.24 EER28370.1 - 6.9e-17 60.8 2.7 1.3e-16 59.9 1.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EER28370.1 - 0.034 13.8 0.2 0.076 12.7 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain Adaptin_N PF01602.15 EER28372.1 - 2.4e-126 422.1 5.1 3.1e-126 421.7 3.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EER28372.1 - 6.1e-42 142.1 0.0 2e-41 140.4 0.0 2.0 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EER28372.1 - 5e-20 71.9 0.0 1.3e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Ala_racemase_N PF01168.15 EER28373.1 - 7.1e-44 149.9 0.0 1.2e-43 149.2 0.0 1.3 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Fungal_trans PF04082.13 EER28375.1 - 5.8e-27 94.1 0.1 1.3e-26 93.0 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28375.1 - 2e-09 37.1 9.1 3.8e-09 36.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PspA_IM30 PF04012.7 EER28375.1 - 0.0056 16.0 2.5 0.014 14.8 1.7 1.5 1 0 0 1 1 1 1 PspA/IM30 family TGT PF01702.13 EER28376.1 - 3.5e-91 304.7 0.0 4.4e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thymidylat_synt PF00303.14 EER28377.1 - 9.4e-111 369.1 0.0 1.1e-110 368.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase zf-AN1 PF01428.11 EER28378.1 - 2.5e-24 84.8 27.8 4.9e-13 48.7 6.2 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EER28378.1 - 0.0044 16.8 3.9 0.0044 16.8 2.7 2.7 2 1 0 2 2 2 1 IBR domain Transp_Tc5_C PF04236.10 EER28378.1 - 0.054 13.7 17.6 0.82 9.9 5.0 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Hist_deacetyl PF00850.14 EER28380.1 - 7.1e-59 199.6 0.1 1.1e-58 199.0 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Peptidase_M28 PF04389.12 EER28381.1 - 2.5e-27 95.7 0.3 3.5e-27 95.2 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EER28381.1 - 0.0084 15.6 0.2 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 bPH_6 PF10756.4 EER28381.1 - 0.043 13.6 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Bacterial PH domain FG-GAP_2 PF14312.1 EER28381.1 - 0.094 12.7 0.9 1.3 9.0 0.6 2.3 1 1 0 1 1 1 0 FG-GAP repeat DUF1774 PF08611.5 EER28382.1 - 5.4e-39 132.2 0.5 5.4e-39 132.2 0.4 1.9 3 0 0 3 3 3 1 Fungal protein of unknown function (DUF1774) DUF2723 PF11028.3 EER28382.1 - 0.00015 21.3 3.8 0.00015 21.3 2.6 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2723) DUF3488 PF11992.3 EER28382.1 - 0.0074 14.9 2.0 0.0074 14.9 1.4 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF3488) DUF4282 PF14110.1 EER28382.1 - 6.1 7.1 15.0 3.4 7.9 0.6 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4282) Protoglobin PF11563.3 EER28383.1 - 1e-55 187.7 0.0 1.2e-55 187.4 0.0 1.1 1 0 0 1 1 1 1 Protoglobin dCMP_cyt_deam_1 PF00383.17 EER28384.1 - 1.3e-07 31.1 0.1 1.6e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MtmB PF05369.7 EER28384.1 - 0.0018 16.5 0.1 0.0021 16.3 0.0 1.1 1 0 0 1 1 1 1 Monomethylamine methyltransferase MtmB Chitin_synth_1 PF01644.12 EER28385.1 - 2.8e-86 287.3 0.1 4.3e-86 286.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EER28385.1 - 1e-33 114.8 0.3 2.6e-33 113.5 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EER28385.1 - 2.1e-22 79.2 1.8 3.2e-21 75.3 0.0 2.3 1 1 1 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EER28385.1 - 7.7e-08 32.2 1.1 7.7e-08 32.2 0.8 2.4 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EER28385.1 - 4.7e-05 23.3 0.0 0.00011 22.0 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 AFG1_ATPase PF03969.11 EER28386.1 - 1.9e-91 306.5 0.0 1.9e-86 290.1 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EER28386.1 - 0.0001 22.3 0.0 0.14 12.0 0.0 2.8 1 1 1 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EER28386.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EER28386.1 - 0.004 17.3 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER28386.1 - 0.073 13.2 0.0 0.22 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EER28386.1 - 0.1 12.7 0.0 0.36 11.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase Bac_DnaA PF00308.13 EER28386.1 - 0.14 11.8 0.2 2.2 7.8 0.1 2.3 2 1 0 2 2 2 0 Bacterial dnaA protein SH3_1 PF00018.23 EER28387.1 - 9.1e-25 85.7 0.0 4.1e-11 42.0 0.0 3.3 4 0 0 4 4 4 2 SH3 domain SH3_9 PF14604.1 EER28387.1 - 1.9e-15 56.1 2.1 1.8e-07 30.5 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 EER28387.1 - 2.9e-13 49.5 0.0 6.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EER28387.1 - 1.9e-10 40.0 0.0 1.8e-06 27.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EER28387.1 - 2.9e-09 36.4 0.9 5.9e-09 35.4 0.6 1.5 1 0 0 1 1 1 1 PB1 domain Pex14_N PF04695.8 EER28387.1 - 3.1 7.8 12.1 0.45 10.5 0.2 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SAC3_GANP PF03399.11 EER28388.1 - 3.3e-69 232.5 0.7 5.2e-69 231.9 0.5 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EER28388.1 - 6.3e-05 22.7 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 EER28389.1 - 1.7e-49 167.9 0.0 2.3e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EER28389.1 - 1.8e-28 98.2 0.0 2.9e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EER28389.1 - 0.00022 20.6 0.0 0.0004 19.8 0.0 1.4 1 0 0 1 1 1 1 GRAM domain zf-RanBP PF00641.13 EER28389.1 - 0.00024 20.1 13.8 0.00053 19.0 0.8 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 EER28389.1 - 0.00087 18.7 4.9 0.0026 17.2 0.3 2.4 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger DZR PF12773.2 EER28389.1 - 0.023 14.5 0.4 0.023 14.5 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon FKBP_C PF00254.23 EER28392.1 - 1.1e-21 76.6 0.0 1.3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase APH PF01636.18 EER28393.1 - 0.00072 19.3 0.0 0.00072 19.3 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EER28393.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) CENP-F_leu_zip PF10473.4 EER28393.1 - 0.23 11.2 8.3 0.093 12.5 3.7 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Peptidase_M43 PF05572.8 EER28394.1 - 3e-17 62.6 0.0 4.2e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EER28394.1 - 2.8e-05 24.1 0.1 3.9e-05 23.6 0.1 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EER28394.1 - 0.00017 22.1 0.0 0.00037 21.0 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EER28394.1 - 0.0013 18.8 0.1 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EER28394.1 - 0.0072 16.0 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Matrixin Peptidase_M7 PF02031.11 EER28394.1 - 0.016 14.9 0.3 0.037 13.7 0.1 1.6 1 1 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_4 PF13583.1 EER28394.1 - 0.08 12.4 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EER28394.1 - 0.15 10.9 0.7 0.22 10.3 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 PHP PF02811.14 EER28396.1 - 1e-11 44.9 0.0 2.8e-11 43.5 0.0 1.7 1 1 0 1 1 1 1 PHP domain ACPS PF01648.15 EER28397.1 - 4e-18 65.3 0.0 6.2e-18 64.6 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Pepsin-I3 PF06394.8 EER28397.1 - 0.12 12.0 0.2 0.18 11.4 0.2 1.2 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain AAT PF03417.11 EER28398.1 - 3.5e-27 95.3 0.0 4.6e-27 94.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EER28398.1 - 4.1e-07 30.2 0.0 7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF2611 PF11022.3 EER28399.1 - 8.2e-27 93.0 0.2 9.2e-27 92.9 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 EER28400.1 - 9.2e-66 220.3 0.1 1.5e-65 219.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) MFS_1 PF07690.11 EER28402.1 - 3.1e-33 114.9 32.8 3.1e-33 114.9 22.8 2.1 3 0 0 3 3 3 1 Major Facilitator Superfamily DUF2530 PF10745.4 EER28402.1 - 0.077 12.9 0.2 0.077 12.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF4131 PF13567.1 EER28402.1 - 4 6.8 10.0 0.82 9.0 0.3 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4131) Cys_Met_Meta_PP PF01053.15 EER28403.1 - 8e-141 468.7 0.0 9.5e-141 468.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EER28403.1 - 0.00015 20.9 0.0 0.00037 19.6 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EER28403.1 - 0.0007 17.9 0.0 0.0083 14.4 0.0 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EER28403.1 - 0.0069 15.5 0.0 0.029 13.5 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase AAA PF00004.24 EER28404.1 - 1.6e-37 128.6 0.0 3.8e-37 127.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EER28404.1 - 8.8e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER28404.1 - 9.6e-06 25.3 0.1 0.00015 21.4 0.1 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EER28404.1 - 1.9e-05 25.4 0.0 8e-05 23.4 0.0 2.2 3 0 0 3 3 1 1 AAA domain AAA_22 PF13401.1 EER28404.1 - 2.3e-05 24.5 0.1 0.00062 19.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER28404.1 - 2.3e-05 24.4 0.1 0.00039 20.4 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EER28404.1 - 3.3e-05 23.0 0.0 6.7e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EER28404.1 - 0.00016 21.6 0.0 0.00033 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EER28404.1 - 0.00024 20.5 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EER28404.1 - 0.00026 20.8 0.0 0.00068 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EER28404.1 - 0.00026 20.4 0.1 0.033 13.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EER28404.1 - 0.0009 18.4 0.1 0.0017 17.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EER28404.1 - 0.00091 19.2 0.0 0.0039 17.2 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EER28404.1 - 0.0012 18.9 0.0 0.0044 17.1 0.0 2.0 1 1 1 2 2 2 1 RNA helicase NACHT PF05729.7 EER28404.1 - 0.0034 17.0 0.0 0.01 15.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EER28404.1 - 0.0038 16.3 0.0 0.0066 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EER28404.1 - 0.0039 17.1 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER28404.1 - 0.0042 16.8 0.1 0.026 14.2 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 EER28404.1 - 0.0058 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EER28404.1 - 0.0062 16.8 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 EER28404.1 - 0.015 14.1 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EER28404.1 - 0.019 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EER28404.1 - 0.024 14.9 0.0 0.066 13.5 0.0 1.9 1 1 0 1 1 1 0 ABC transporter SKI PF01202.17 EER28404.1 - 0.038 13.8 1.8 0.25 11.2 0.0 2.7 3 0 0 3 3 3 0 Shikimate kinase CPT PF07931.7 EER28404.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.8 EER28404.1 - 0.07 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EER28404.1 - 0.079 12.6 0.0 0.26 10.9 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 EER28404.1 - 0.081 11.5 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 EER28404.1 - 0.095 12.2 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EER28404.1 - 0.1 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 EER28404.1 - 0.11 11.1 0.1 0.3 9.7 0.0 1.7 2 0 0 2 2 2 0 TIP49 C-terminus AAA_10 PF12846.2 EER28404.1 - 0.12 11.7 0.2 1.8 7.9 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Viral_helicase1 PF01443.13 EER28404.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 EER28404.1 - 0.14 11.2 0.0 0.65 9.0 0.0 1.9 1 1 1 2 2 2 0 KaiC Csm1 PF12539.3 EER28405.1 - 2e-27 95.5 0.3 5.9e-27 93.9 0.1 1.9 2 0 0 2 2 1 1 Chromosome segregation protein Csm1/Pcs1 Spc42p PF11544.3 EER28405.1 - 4.3e-05 23.3 0.8 0.00023 20.9 0.1 2.4 2 0 0 2 2 2 1 Spindle pole body component Spc42p AAA_13 PF13166.1 EER28405.1 - 7.7e-05 21.3 1.0 7.7e-05 21.3 0.7 2.0 2 0 0 2 2 2 1 AAA domain Reo_sigmaC PF04582.7 EER28405.1 - 0.00092 18.4 2.5 0.0019 17.4 1.7 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein GAS PF13851.1 EER28405.1 - 0.033 13.3 9.8 0.096 11.8 6.8 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EER28405.1 - 0.035 13.8 4.4 0.043 13.6 2.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.4 EER28405.1 - 0.044 13.1 6.3 0.079 12.3 0.1 3.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Spc7 PF08317.6 EER28405.1 - 0.058 12.0 9.9 0.11 11.1 6.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EER28405.1 - 0.064 11.1 1.3 0.086 10.6 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EER28405.1 - 0.078 13.1 3.4 0.17 11.9 2.4 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.1 EER28405.1 - 0.084 12.3 8.1 0.23 10.9 2.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Flagellin_C PF00700.16 EER28405.1 - 0.11 12.7 5.5 5.7 7.1 0.3 2.7 1 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region SOCS_box PF07525.11 EER28405.1 - 0.12 12.2 0.4 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 SOCS box Bacillus_HBL PF05791.6 EER28405.1 - 0.19 11.1 3.0 0.47 9.7 2.1 1.7 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TMF_TATA_bd PF12325.3 EER28405.1 - 0.26 10.9 10.2 0.4 10.4 5.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding TBPIP PF07106.8 EER28405.1 - 0.76 9.3 8.5 1.1 8.8 1.1 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Nup54 PF13874.1 EER28405.1 - 1.1 8.8 9.3 0.99 9.0 3.8 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Prominin PF05478.6 EER28405.1 - 1.2 6.6 3.6 1.6 6.1 2.5 1.1 1 0 0 1 1 1 0 Prominin KxDL PF10241.4 EER28405.1 - 1.9 8.4 6.9 1.2 9.1 2.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein COG5 PF10392.4 EER28405.1 - 2.3 8.1 7.5 11 5.9 0.2 2.5 1 1 1 2 2 2 0 Golgi transport complex subunit 5 COG2 PF06148.6 EER28405.1 - 3.2 7.6 6.6 1.1e+02 2.6 4.6 2.4 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cluap1 PF10234.4 EER28405.1 - 4.5 6.4 11.6 1.5 7.9 3.6 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 PigN PF04987.9 EER28406.1 - 2.9e-171 569.9 37.1 3.8e-171 569.6 25.7 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EER28406.1 - 3.1e-11 43.1 0.8 3.5e-10 39.7 0.1 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EER28406.1 - 1.7e-09 37.3 0.1 2.8e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EER28406.1 - 0.0076 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Fungal_trans PF04082.13 EER28407.1 - 6.5e-33 113.7 0.1 3.4e-32 111.3 0.0 2.1 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28407.1 - 8.2e-08 32.0 8.4 1.4e-07 31.2 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_2 PF07727.9 EER28410.1 - 7.3e-69 231.4 0.0 2.2e-68 229.8 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EER28410.1 - 3.5e-19 69.0 0.0 1.9e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EER28410.1 - 3.1e-06 26.7 0.1 7.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EER28410.1 - 1.2e-05 25.0 2.3 2.3e-05 24.0 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Phage_Gp23 PF10669.4 EER28410.1 - 0.8 9.8 10.1 0.062 13.4 2.0 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) adh_short PF00106.20 EER28411.1 - 2e-58 197.0 6.2 1.1e-28 100.2 0.1 2.6 3 0 0 3 3 3 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EER28411.1 - 2.7e-30 104.2 0.0 5.7e-30 103.2 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EER28411.1 - 3e-26 92.2 1.4 4.1e-12 46.1 0.0 2.5 3 0 0 3 3 3 2 KR domain THF_DHG_CYH_C PF02882.14 EER28411.1 - 0.00022 20.3 0.4 0.055 12.5 0.2 2.6 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 EER28411.1 - 0.17 12.2 0.7 6.8 7.0 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) IBR PF01485.16 EER28412.1 - 2e-06 27.5 2.0 2e-06 27.5 1.4 4.9 5 0 0 5 5 5 3 IBR domain Yip1 PF04893.12 EER28413.1 - 6.5e-14 51.7 17.6 1.2e-13 50.9 12.2 1.5 1 1 0 1 1 1 1 Yip1 domain 7TM_transglut PF14402.1 EER28413.1 - 3.8 6.3 10.4 5.1 5.9 7.2 1.1 1 0 0 1 1 1 0 7 transmembrane helices usually fused to an inactive transglutaminase Ran_BP1 PF00638.13 EER28414.1 - 2.1e-16 60.0 0.0 4.3e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain DEAD PF00270.24 EER28415.1 - 3e-25 88.6 0.0 5.2e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EER28415.1 - 7.5e-11 42.4 0.0 7.8e-10 39.1 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EER28415.1 - 7.5e-11 41.7 0.0 2.3e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EER28415.1 - 0.0023 17.8 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like Fungal_trans_2 PF11951.3 EER28416.1 - 3.3e-11 42.4 0.4 5.7e-11 41.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28416.1 - 1.2e-05 25.0 9.5 2.6e-05 24.0 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 EER28417.1 - 1.4e-12 47.0 0.6 4.6e-08 32.5 0.3 2.3 1 1 0 2 2 2 2 TPR repeat TPR_9 PF13371.1 EER28417.1 - 2.3e-08 33.7 0.1 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EER28417.1 - 4e-08 32.5 2.2 0.0047 16.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EER28417.1 - 2.6e-07 29.9 1.1 0.023 14.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EER28417.1 - 3.1e-05 24.0 0.0 7.2e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EER28417.1 - 3.4e-05 23.7 0.8 0.14 12.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER28417.1 - 0.00063 20.3 1.6 0.71 10.6 1.2 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER28417.1 - 0.001 18.6 0.6 1.6 8.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EER28417.1 - 0.0014 19.0 2.3 0.062 13.9 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EER28417.1 - 0.0054 16.4 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER28417.1 - 0.0084 16.4 0.6 0.13 12.5 0.0 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EER28417.1 - 0.014 15.8 1.5 0.13 12.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ceramidase PF05875.7 EER28418.1 - 2.1e-33 115.6 2.6 2.3e-33 115.4 1.8 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 EER28418.1 - 0.049 13.2 4.8 0.21 11.3 3.3 2.1 1 0 0 1 1 1 0 Trp-operon Leader Peptide PrgI PF12666.2 EER28418.1 - 1.1 9.3 7.2 1.6 8.9 0.8 3.0 1 1 2 3 3 3 0 PrgI family protein zf-RING_2 PF13639.1 EER28419.1 - 2.6e-14 52.7 4.7 5e-14 51.8 3.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EER28419.1 - 1e-09 38.3 1.8 1.7e-09 37.6 1.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EER28419.1 - 2.7e-07 30.4 4.4 4.7e-07 29.7 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER28419.1 - 1e-06 28.2 4.2 1.6e-06 27.6 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER28419.1 - 1.2e-06 28.1 2.6 1.8e-06 27.5 1.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EER28419.1 - 5.3e-06 25.9 1.9 8.3e-06 25.3 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EER28419.1 - 7.2e-05 22.5 1.5 0.00021 21.0 1.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EER28419.1 - 0.0012 18.7 5.9 0.002 18.1 4.1 1.3 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EER28419.1 - 0.022 14.7 3.3 0.041 13.8 2.3 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EER28419.1 - 0.03 13.8 1.4 0.054 13.0 1.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EER28419.1 - 0.056 13.1 0.9 0.12 12.0 0.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF4019 PF13211.1 EER28419.1 - 0.067 13.4 0.5 0.26 11.5 0.0 2.2 3 0 0 3 3 2 0 Protein of unknown function (DUF4019) Prok-RING_1 PF14446.1 EER28419.1 - 0.24 11.1 4.1 0.52 10.0 2.8 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EER28419.1 - 0.32 11.0 1.6 0.58 10.2 1.1 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 EER28419.1 - 1.5 8.4 3.1 2.7 7.6 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ECM11 PF15463.1 EER28420.1 - 5.2e-40 136.9 0.0 5.2e-40 136.9 0.0 3.0 3 0 0 3 3 3 1 Extracellular mutant protein 11 RNA_pol_I_TF PF04090.7 EER28420.1 - 1e-07 31.4 0.0 0.0001 21.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor bZIP_2 PF07716.10 EER28421.1 - 6e-05 22.7 12.0 6e-05 22.7 8.3 3.4 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EER28421.1 - 0.00018 21.7 15.4 0.00018 21.7 10.7 3.6 2 2 2 4 4 4 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EER28421.1 - 0.00019 21.3 10.2 0.00019 21.3 7.1 3.5 1 1 2 3 3 3 1 bZIP transcription factor DUF2205 PF10224.4 EER28421.1 - 2.5 7.7 15.0 0.62 9.6 6.5 2.5 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) zf-CCCH PF00642.19 EER28422.1 - 4.9e-16 57.9 22.1 2.5e-05 23.8 0.9 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1936 PF09151.5 EER28422.1 - 0.43 10.1 4.6 0.17 11.4 0.3 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1936) LRV_FeS PF05484.6 EER28422.1 - 3.1 7.4 6.7 11 5.6 0.2 3.5 2 1 1 3 3 3 0 LRV protein FeS4 cluster TFIIF_beta PF02270.10 EER28423.1 - 1e-88 297.7 6.0 1.2e-88 297.5 4.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit PCI PF01399.22 EER28424.1 - 3.1e-12 46.7 0.0 7.9e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 EER28424.1 - 2.8e-06 26.8 0.0 5.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 EER28424.1 - 0.13 12.6 5.1 12 6.3 0.2 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat SLAC1 PF03595.12 EER28425.1 - 3.6e-54 183.6 35.7 5e-54 183.1 24.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ATP_synth_reg PF14960.1 EER28425.1 - 0.092 11.9 0.2 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 ATP synthase regulation WD40 PF00400.27 EER28426.1 - 2.7e-13 49.2 3.0 0.071 13.0 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat FAD_binding_2 PF00890.19 EER28428.1 - 8.7e-85 285.0 0.3 1.1e-84 284.7 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EER28428.1 - 3.5e-22 78.0 1.0 2.3e-19 68.9 0.1 3.5 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EER28428.1 - 4.6e-14 52.0 1.3 4e-13 49.0 0.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EER28428.1 - 5e-10 39.0 0.3 1.8e-09 37.2 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER28428.1 - 5.2e-09 35.9 2.5 7.5e-08 32.2 0.4 3.1 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER28428.1 - 3e-07 30.5 0.0 0.011 15.5 0.2 2.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EER28428.1 - 2.9e-06 26.0 4.3 8.6e-05 21.1 0.8 3.0 2 1 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EER28428.1 - 9.5e-06 24.9 0.3 0.023 13.7 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Thi4 PF01946.12 EER28428.1 - 1.8e-05 23.9 0.8 0.0097 15.0 0.2 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EER28428.1 - 0.00021 20.2 1.3 0.15 10.9 0.3 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EER28428.1 - 0.0038 16.3 1.3 0.0087 15.1 0.9 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EER28428.1 - 0.0045 16.7 0.8 0.068 12.9 0.5 2.6 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EER28428.1 - 0.0087 16.1 1.0 0.049 13.6 0.7 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER28428.1 - 0.016 15.5 0.8 1.4 9.3 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EER28428.1 - 0.12 11.2 0.4 6.7 5.5 0.0 2.7 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) GDI PF00996.13 EER28428.1 - 0.22 9.8 0.0 0.33 9.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor PAH PF02671.16 EER28429.1 - 1.3e-45 152.7 2.8 6.7e-17 60.8 0.3 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EER28429.1 - 6.6e-38 128.5 0.1 6.6e-38 128.5 0.0 2.3 3 0 0 3 3 3 1 Sin3 family co-repressor AcetylCoA_hydro PF02550.10 EER28430.1 - 1.5e-48 165.1 0.0 2.3e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EER28430.1 - 1.8e-38 131.6 0.0 3.1e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Abhydrolase_6 PF12697.2 EER28431.1 - 4.9e-20 72.3 6.8 4.9e-20 72.3 4.7 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER28431.1 - 9.2e-09 35.1 0.1 1.6e-08 34.3 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER28431.1 - 5.5e-08 32.6 0.0 9.7e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_17 PF00332.13 EER28432.1 - 0.0032 16.5 0.2 0.54 9.2 0.1 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 17 Penaeidin PF05927.6 EER28432.1 - 0.06 13.8 0.0 0.26 11.8 0.0 2.1 1 0 0 1 1 1 0 Penaeidin APH PF01636.18 EER28433.1 - 2.3e-12 47.1 0.0 6.9e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EER28433.1 - 0.0061 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase DUF3759 PF12585.3 EER28434.1 - 0.028 14.3 4.0 0.052 13.4 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3759) WD40 PF00400.27 EER28435.1 - 6.1e-09 35.4 0.9 3.2e-08 33.1 0.1 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF1582 PF07621.6 EER28435.1 - 0.049 13.6 0.0 0.27 11.2 0.0 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1582) Chitin_synth_2 PF03142.10 EER28436.1 - 1.2e-295 980.9 0.3 1.6e-295 980.5 0.2 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EER28436.1 - 7.3e-19 68.2 0.1 2e-18 66.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EER28436.1 - 4.7e-15 56.0 0.0 1.9e-13 50.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EER28436.1 - 2.6e-11 43.1 0.1 8.3e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EER28436.1 - 3.4e-05 23.1 0.0 0.00058 19.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EER28436.1 - 0.0051 16.5 0.0 0.32 10.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Flavi_NS4B PF01349.12 EER28436.1 - 0.13 11.1 0.0 0.24 10.2 0.0 1.4 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4B Sel1 PF08238.7 EER28437.1 - 4e-31 106.7 32.7 7.7e-05 23.1 0.1 7.7 7 0 0 7 7 7 7 Sel1 repeat MFS_1 PF07690.11 EER28438.1 - 1.7e-40 138.8 61.5 8.6e-39 133.2 44.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER28438.1 - 5.1e-14 51.7 12.0 5.1e-14 51.7 8.3 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EER28438.1 - 8.5e-14 50.6 31.0 1.6e-13 49.7 21.5 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Myosin_head PF00063.16 EER28439.1 - 3.2e-231 769.1 4.9 4.9e-231 768.5 3.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EER28439.1 - 3e-46 157.2 0.0 5.5e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EER28439.1 - 3e-14 52.1 0.0 7.1e-14 50.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EER28439.1 - 1.6e-10 40.3 0.1 6.9e-10 38.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EER28439.1 - 1.1e-09 37.6 0.0 4.3e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain AAA_22 PF13401.1 EER28439.1 - 0.0019 18.3 0.0 0.0081 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain IQ PF00612.22 EER28439.1 - 0.0035 16.8 6.3 0.66 9.7 0.4 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.7 EER28439.1 - 0.012 14.9 0.5 1.4 8.1 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 EER28439.1 - 0.019 15.7 0.0 0.068 14.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 EER28439.1 - 0.022 13.8 0.0 0.057 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EER28439.1 - 0.055 13.7 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EER28439.1 - 0.087 12.4 0.0 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 EER28439.1 - 0.089 11.4 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.17 EER28439.1 - 0.11 12.6 0.0 0.36 11.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase OPA3 PF07047.7 EER28440.1 - 2.4e-33 114.7 0.5 5.3e-33 113.6 0.3 1.6 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF1070 PF06376.7 EER28440.1 - 0.045 13.6 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1070) Med11 PF10280.4 EER28440.1 - 0.19 11.8 2.8 0.12 12.4 0.3 1.8 2 1 0 2 2 2 0 Mediator complex protein DUF3987 PF13148.1 EER28440.1 - 2.4 6.6 15.1 0.16 10.4 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF3318 PF11780.3 EER28440.1 - 2.5 7.6 0.0 2.5 7.6 0.0 3.8 3 2 2 5 5 5 0 Protein of unknown function (DUF3318) DUF3306 PF11748.3 EER28440.1 - 7.5 7.2 12.4 5.6 7.6 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Pkinase PF00069.20 EER28441.1 - 1.6e-69 233.9 0.0 2.9e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER28441.1 - 7.7e-44 149.7 0.0 1.2e-43 149.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EER28441.1 - 3.9e-07 29.9 0.2 0.03 14.2 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EER28441.1 - 4.4e-06 25.8 0.0 1.3e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like MerB PF03243.10 EER28441.1 - 0.053 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Alkylmercury lyase zf-DHHC PF01529.15 EER28442.1 - 2.3e-37 128.0 1.1 3.9e-37 127.3 0.8 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DNA_mis_repair PF01119.14 EER28443.1 - 4.7e-10 38.9 0.0 1.3e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EER28443.1 - 5.9e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EER28443.1 - 8.2e-09 35.2 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SET PF00856.23 EER28444.1 - 2.5e-06 27.9 0.0 4.4e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 SET domain cobW PF02492.14 EER28445.1 - 2.7e-38 131.2 0.0 3.7e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EER28445.1 - 0.0049 16.5 0.0 0.014 15.1 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EER28445.1 - 0.0089 15.7 0.1 0.024 14.4 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EER28445.1 - 0.031 14.4 0.0 0.098 12.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain CobW_C PF07683.9 EER28445.1 - 0.052 13.2 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain Viral_helicase1 PF01443.13 EER28445.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EER28445.1 - 0.071 13.0 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EER28445.1 - 0.094 12.2 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EER28445.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EER28445.1 - 0.14 11.4 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Poxvirus A32 protein Orn_Arg_deC_N PF02784.11 EER28446.1 - 1.1e-78 263.9 0.0 1.4e-78 263.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EER28446.1 - 7.7e-30 102.9 0.1 1.3e-29 102.2 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EER28446.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Methyltransf_16 PF10294.4 EER28447.1 - 6.2e-50 169.0 0.0 8e-50 168.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EER28447.1 - 2e-05 24.1 0.0 2.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER28447.1 - 0.00011 22.7 0.0 0.00032 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER28447.1 - 0.00031 20.1 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EER28447.1 - 0.00047 19.9 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER28447.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EER28447.1 - 0.0032 16.8 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EER28447.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FTCD_C PF04961.7 EER28447.1 - 0.031 13.7 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase PCMT PF01135.14 EER28447.1 - 0.041 13.4 0.0 0.093 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EER28447.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2416 PF10315.4 EER28447.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) GidB PF02527.10 EER28447.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G DSBA PF01323.15 EER28449.1 - 7.2e-13 48.5 0.0 8.5e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Mitofilin PF09731.4 EER28454.1 - 2.5e-151 505.2 19.8 3.4e-151 504.8 13.7 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein Pex14_N PF04695.8 EER28454.1 - 0.11 12.5 0.1 0.11 12.5 0.0 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1640 PF07798.6 EER28454.1 - 0.96 9.4 10.8 0.67 9.9 5.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Ras PF00071.17 EER28455.1 - 2.7e-59 199.1 0.2 3.1e-59 198.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER28455.1 - 1.6e-19 70.5 0.0 2.7e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER28455.1 - 8e-15 54.5 0.0 9.9e-15 54.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER28455.1 - 9.8e-08 31.4 0.0 1.2e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EER28455.1 - 1.2e-07 31.4 0.0 2.1e-07 30.5 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EER28455.1 - 4.1e-06 26.7 0.0 7.2e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EER28455.1 - 0.0081 16.3 0.1 1.1 9.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EER28455.1 - 0.021 14.8 0.2 0.082 12.8 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EER28455.1 - 0.027 13.6 0.2 0.094 11.8 0.0 1.9 2 1 0 3 3 3 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EER28455.1 - 0.073 12.2 0.1 0.17 11.0 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EER28455.1 - 0.095 12.6 0.1 0.17 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain Syja_N PF02383.13 EER28456.1 - 1e-91 307.0 0.0 1.2e-91 306.7 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Mur_ligase_M PF08245.7 EER28457.1 - 1e-05 25.6 0.0 0.00045 20.3 0.0 2.9 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EER28457.1 - 0.11 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain NMT PF01233.14 EER28458.1 - 4.6e-81 270.1 0.0 1.1e-80 268.9 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EER28458.1 - 5e-78 260.8 0.0 7.9e-78 260.2 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EER28458.1 - 1.9e-07 30.9 0.0 5.8e-06 26.1 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EER28458.1 - 0.00051 20.2 0.0 0.0018 18.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain ATP-grasp_5 PF13549.1 EER28458.1 - 0.048 12.8 0.1 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 ATP-grasp domain TLD PF07534.11 EER28459.1 - 1.5e-16 60.6 0.0 2.8e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 TLD MUG2_C PF08593.5 EER28459.1 - 0.0013 18.9 1.0 0.0029 17.8 0.7 1.6 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal VanY PF02557.12 EER28459.1 - 0.15 11.9 0.2 4 7.2 0.0 2.3 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Abhydrolase_5 PF12695.2 EER28461.1 - 4.4e-12 45.9 0.0 1.5e-11 44.2 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER28461.1 - 7.3e-11 42.3 0.2 1.1e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EER28461.1 - 2.1e-07 30.7 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EER28461.1 - 0.0046 16.5 0.0 0.0062 16.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EER28461.1 - 0.086 12.7 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase GTP_EFTU PF00009.22 EER28462.1 - 8.1e-56 188.4 0.2 1.5e-55 187.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EER28462.1 - 2.5e-33 113.7 0.0 5.1e-33 112.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EER28462.1 - 6.5e-30 103.1 0.0 1.2e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EER28462.1 - 1.1e-23 82.8 0.0 2.9e-23 81.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EER28462.1 - 4.8e-12 45.8 0.1 1.2e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.12 EER28462.1 - 0.029 13.9 0.1 0.083 12.4 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Ribosomal_L36 PF00444.13 EER28463.1 - 7e-20 70.7 9.7 1e-19 70.2 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 EER28463.1 - 0.03 13.6 0.3 0.16 11.2 0.4 1.8 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family PALP PF00291.20 EER28464.1 - 2e-71 240.7 0.8 2.7e-71 240.3 0.6 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EER28464.1 - 2.6e-44 148.7 0.0 6.1e-22 77.0 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 EER28465.1 - 1.3e-24 85.7 0.0 2.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2681 PF10883.3 EER28465.1 - 0.0059 16.7 0.8 0.02 15.0 0.4 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2681) Acetyltransf_1 PF00583.19 EER28466.1 - 7.2e-14 51.5 0.0 1.2e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EER28466.1 - 0.00067 19.6 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER28466.1 - 0.0014 18.3 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EER28466.1 - 0.0023 18.0 0.1 0.0038 17.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER28466.1 - 0.028 14.5 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-U PF06728.8 EER28467.1 - 3.8e-109 365.0 20.3 7.4e-108 360.8 14.1 2.0 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 EER28468.1 - 1.1e-113 379.2 0.0 1.1e-113 379.2 0.0 2.2 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 EER28468.1 - 4.3e-06 26.7 0.0 3.7e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RRN9 PF10680.4 EER28469.1 - 4.5e-19 67.9 0.7 1.6e-18 66.2 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 EER28469.1 - 0.31 11.4 1.8 1 9.8 1.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1673 PF07895.6 EER28470.1 - 0.059 12.9 2.9 0.11 11.9 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Aldedh PF00171.17 EER28471.1 - 3.9e-162 539.7 0.0 4.4e-162 539.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EER28471.1 - 0.04 12.6 0.0 0.057 12.1 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Raffinose_syn PF05691.7 EER28472.1 - 1.3e-56 191.6 0.5 9.2e-53 178.8 1.5 3.3 1 1 1 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 EER28472.1 - 0.00086 18.1 0.5 0.0014 17.4 0.3 1.2 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.20 EER28473.1 - 1.7e-70 237.4 0.0 2.4e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 EER28473.1 - 0.061 12.7 0.1 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 S4 domain MutS_V PF00488.16 EER28474.1 - 4.3e-80 268.4 0.0 7.2e-80 267.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EER28474.1 - 2.7e-50 171.0 0.0 5.5e-50 169.9 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EER28474.1 - 9.5e-34 115.8 0.2 2.8e-33 114.3 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EER28474.1 - 8.2e-15 55.0 0.0 2e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EER28474.1 - 4.7e-13 49.1 0.4 1.2e-12 47.8 0.3 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 EER28474.1 - 0.025 14.8 2.3 0.19 12.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EER28474.1 - 0.043 13.7 0.6 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EER28474.1 - 0.046 13.2 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1858 PF08984.6 EER28474.1 - 0.08 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) Rhodanese PF00581.15 EER28475.1 - 5.2e-10 39.6 0.0 8.1e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Pro-rich_19 PF15455.1 EER28475.1 - 0.11 11.4 0.2 0.15 11.0 0.1 1.1 1 0 0 1 1 1 0 Proline-rich 19 Peptidase_M28 PF04389.12 EER28478.1 - 1.5e-34 119.3 0.0 2.5e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Sulf_transp PF04143.9 EER28479.1 - 2.1e-11 43.6 26.3 1.9e-07 31.0 5.2 4.8 5 1 0 5 5 5 2 Sulphur transport DUF4341 PF14241.1 EER28479.1 - 6.5e-09 35.3 1.0 6.5e-09 35.3 0.7 3.3 4 1 1 5 5 5 1 Domain of unknown function (DUF4341) PAP2 PF01569.16 EER28479.1 - 0.036 13.7 0.4 0.1 12.2 0.3 2.1 1 1 0 1 1 1 0 PAP2 superfamily LigD_N PF13298.1 EER28480.1 - 3.3e-17 62.5 0.0 1e-09 38.4 0.0 3.1 2 1 0 2 2 2 2 DNA polymerase Ligase (LigD) ABC_tran PF00005.22 EER28481.1 - 8.9e-48 162.0 0.0 2e-28 99.3 0.0 3.1 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EER28481.1 - 1.6e-32 113.0 38.0 1.8e-21 76.8 9.5 3.2 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EER28481.1 - 3.4e-10 39.5 0.0 0.016 14.4 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EER28481.1 - 1.4e-05 25.5 0.1 0.001 19.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EER28481.1 - 2.4e-05 23.7 0.4 0.032 13.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EER28481.1 - 0.00016 20.7 0.0 0.047 12.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EER28481.1 - 0.00018 20.9 0.1 0.2 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EER28481.1 - 0.0011 18.1 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EER28481.1 - 0.0014 18.5 0.0 0.5 10.3 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EER28481.1 - 0.0018 18.2 0.0 1.5 8.7 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EER28481.1 - 0.002 18.1 0.0 5.4 6.8 0.0 3.8 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EER28481.1 - 0.0024 17.7 1.7 0.68 9.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 EER28481.1 - 0.0028 18.1 0.0 5.3 7.5 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EER28481.1 - 0.003 17.6 0.0 3.3 7.8 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EER28481.1 - 0.0032 16.9 0.0 2.9 7.2 0.0 3.2 3 0 0 3 3 3 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EER28481.1 - 0.02 14.3 0.0 5 6.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EER28481.1 - 0.039 14.7 0.5 15 6.4 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EER28481.1 - 0.056 13.1 0.2 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Zeta_toxin PF06414.7 EER28481.1 - 0.094 11.8 0.1 11 5.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PEP_mutase PF13714.1 EER28482.1 - 3.2e-63 213.1 3.2 3.6e-63 212.9 2.2 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase tRNA-synt_2 PF00152.15 EER28483.1 - 2.7e-106 355.1 0.0 3.6e-106 354.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EER28483.1 - 5e-05 22.9 0.1 9.2e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-codon PF01336.20 EER28483.1 - 0.033 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CS PF04969.11 EER28484.1 - 6.6e-17 61.8 0.0 1.3e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 CS domain Spt5-NGN PF03439.8 EER28485.1 - 3.1e-24 84.5 0.0 5.5e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EER28485.1 - 2.4e-22 79.6 46.6 1.6e-20 73.7 23.8 3.1 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5_N PF11942.3 EER28485.1 - 1.4e-16 60.8 13.8 1.4e-16 60.8 9.6 4.1 2 1 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EER28485.1 - 3.2e-14 51.9 15.7 0.00032 20.3 0.0 5.0 4 0 0 4 4 4 4 KOW motif Acyl-CoA_dh_1 PF00441.19 EER28486.1 - 2.6e-41 141.2 0.4 3.6e-41 140.7 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EER28486.1 - 5.7e-21 73.7 0.1 9.9e-21 73.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EER28486.1 - 2.5e-18 66.7 0.0 6.6e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Cyt-b5 PF00173.23 EER28486.1 - 1.3e-17 63.3 0.2 2.3e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 EER28486.1 - 1.1e-08 35.3 0.0 1.7e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_60s PF00428.14 EER28486.1 - 0.32 11.4 3.0 0.62 10.5 2.1 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein TALPID3 PF15324.1 EER28486.1 - 5.3 4.2 8.9 7.6 3.7 6.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target PC_rep PF01851.17 EER28487.1 - 3.6e-37 124.5 15.2 5.4e-09 35.7 0.0 9.8 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EER28487.1 - 9.9e-18 64.2 0.2 1.9e-12 47.2 0.0 4.2 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EER28487.1 - 1.5e-07 31.6 0.8 9.1e-06 26.0 0.0 4.1 3 1 1 4 4 4 1 HEAT-like repeat HEAT PF02985.17 EER28487.1 - 1.8e-07 30.6 0.9 1.4 9.2 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_PBS PF03130.11 EER28487.1 - 0.084 13.3 1.4 1.6 9.4 0.0 3.8 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat TMF_TATA_bd PF12325.3 EER28488.1 - 0.00036 20.2 6.5 0.043 13.5 2.5 2.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.17 EER28488.1 - 0.00092 19.2 12.6 0.067 13.2 1.8 3.7 4 2 0 4 4 3 2 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 EER28488.1 - 0.0012 18.4 5.6 0.0012 18.4 3.9 2.5 2 0 0 2 2 2 1 IncA protein Mod_r PF07200.8 EER28488.1 - 0.0021 17.9 3.1 0.0021 17.9 2.1 2.4 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Myosin_tail_1 PF01576.14 EER28488.1 - 0.003 15.3 2.2 0.003 15.3 1.6 1.8 2 0 0 2 2 2 1 Myosin tail CENP-H PF05837.7 EER28488.1 - 0.0042 17.2 2.9 0.0042 17.2 2.0 2.9 2 1 1 3 3 3 1 Centromere protein H (CENP-H) GAS PF13851.1 EER28488.1 - 0.0046 16.1 7.5 0.11 11.6 2.8 2.3 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.5 EER28488.1 - 0.0088 16.1 0.9 0.0088 16.1 0.6 2.4 2 0 0 2 2 2 1 Fibrinogen alpha/beta chain family DUF465 PF04325.8 EER28488.1 - 0.023 14.3 3.5 2.1 8.0 0.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF465) DivIC PF04977.10 EER28488.1 - 0.023 14.1 0.9 0.023 14.1 0.6 2.5 3 0 0 3 3 2 0 Septum formation initiator Baculo_PEP_C PF04513.7 EER28488.1 - 0.1 12.4 0.2 0.1 12.4 0.1 2.5 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sec5 PF15469.1 EER28488.1 - 0.11 12.2 4.4 4.3 7.0 0.1 2.3 2 0 0 2 2 2 0 Exocyst complex component Sec5 Tropomyosin_1 PF12718.2 EER28488.1 - 0.13 12.0 8.3 0.16 11.8 2.9 2.3 2 0 0 2 2 2 0 Tropomyosin like DUF1664 PF07889.7 EER28488.1 - 0.36 10.6 6.5 0.11 12.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EER28488.1 - 0.39 10.2 7.9 0.16 11.5 1.5 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 EER28488.1 - 0.5 8.7 3.0 0.45 8.8 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Filament PF00038.16 EER28488.1 - 0.87 8.9 9.2 0.19 11.1 2.6 2.2 2 0 0 2 2 2 0 Intermediate filament protein STAT_alpha PF01017.15 EER28488.1 - 1.3 8.7 9.1 0.81 9.3 3.7 2.4 2 1 0 2 2 2 0 STAT protein, all-alpha domain APG6 PF04111.7 EER28488.1 - 1.5 7.7 8.8 0.55 9.2 2.8 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 EER28488.1 - 1.5 7.3 8.9 0.26 9.9 2.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein HALZ PF02183.13 EER28488.1 - 2 8.1 5.1 1.8 8.3 0.8 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper Spc24 PF08286.6 EER28488.1 - 2.1 8.0 5.6 1.7 8.3 1.7 2.5 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 CENP-F_leu_zip PF10473.4 EER28488.1 - 5.8 6.7 13.6 0.33 10.7 3.8 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EER28488.1 - 7.7 5.5 9.2 0.42 9.7 0.4 2.5 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Abhydrolase_5 PF12695.2 EER28489.1 - 0.00074 19.2 0.0 0.0013 18.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3336 PF11815.3 EER28490.1 - 5.4e-35 120.0 1.3 9.3e-35 119.2 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EER28490.1 - 1.5e-20 74.0 0.1 3.4e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase MFS_1 PF07690.11 EER28491.1 - 1.6e-26 92.8 34.5 3.7e-26 91.6 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER28491.1 - 2.9e-10 39.3 4.5 2.9e-10 39.3 3.1 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter Ctr PF04145.10 EER28491.1 - 0.01 15.9 0.4 3.9 7.5 0.1 2.7 2 0 0 2 2 2 0 Ctr copper transporter family ERGIC_N PF13850.1 EER28491.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TMEM154 PF15102.1 EER28493.1 - 0.0037 16.9 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family RCR PF12273.3 EER28493.1 - 0.019 15.5 4.0 0.044 14.3 2.7 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Herpes_gE PF02480.11 EER28493.1 - 0.02 13.1 0.0 0.031 12.5 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4448 PF14610.1 EER28493.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Med8 PF10232.4 EER28494.1 - 6.9e-48 163.1 0.2 8.4e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YPEB PF14620.1 EER28494.1 - 0.023 13.7 0.1 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 YpeB sporulation BSP_II PF05432.6 EER28494.1 - 0.029 13.6 10.1 0.044 13.0 7.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) EB_dh PF09459.5 EER28494.1 - 0.088 12.2 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase Nucleoplasmin PF03066.10 EER28494.1 - 0.25 10.8 8.1 0.38 10.2 5.6 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EER28494.1 - 0.98 9.7 8.0 2.1 8.6 5.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Daxx PF03344.10 EER28494.1 - 1.4 7.3 6.4 1.8 6.9 4.5 1.1 1 0 0 1 1 1 0 Daxx Family Syntaxin PF00804.20 EER28494.1 - 1.7 8.8 6.5 4.7 7.4 0.0 3.0 3 0 0 3 3 3 0 Syntaxin RNA_pol_3_Rpc31 PF11705.3 EER28494.1 - 2.6 7.9 9.8 4.6 7.1 6.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PQ-loop PF04193.9 EER28495.1 - 1.1e-19 69.7 10.6 7.7e-12 44.5 0.6 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF4383 PF14325.1 EER28495.1 - 1.3 9.0 11.9 4.8 7.2 8.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) UbiA PF01040.13 EER28496.1 - 1.5e-31 109.5 20.2 1.5e-31 109.5 14.0 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family Zn_clus PF00172.13 EER28497.1 - 3e-09 36.6 9.4 7.5e-09 35.3 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EER28497.1 - 1.3e-07 30.6 0.4 1.8e-07 30.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain OmdA PF13376.1 EER28497.1 - 0.2 11.3 0.4 0.42 10.3 0.3 1.5 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated F-box PF00646.28 EER28498.1 - 0.1 12.3 0.3 0.1 12.3 0.2 3.1 3 0 0 3 3 3 0 F-box domain CTP_transf_2 PF01467.21 EER28499.1 - 0.0048 16.9 3.1 0.068 13.2 2.1 2.5 1 1 0 1 1 1 1 Cytidylyltransferase WD40 PF00400.27 EER28500.1 - 1.2e-21 75.6 15.2 3.2e-08 33.1 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat mRNA_triPase PF02940.10 EER28501.1 - 1.3e-55 188.5 0.0 2e-55 187.8 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Kelch_4 PF13418.1 EER28502.1 - 6.4e-19 67.4 2.4 9.1e-09 34.9 0.0 5.2 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EER28502.1 - 5.4e-17 61.4 8.5 2.9e-09 36.8 0.0 5.3 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EER28502.1 - 4.1e-10 39.3 5.5 0.0026 17.6 0.3 4.7 4 1 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EER28502.1 - 9e-09 34.7 0.0 0.091 12.3 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EER28502.1 - 6.1e-08 32.5 3.3 0.5 10.6 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EER28502.1 - 6.3e-08 32.0 0.9 0.003 17.2 0.0 4.4 3 1 0 3 3 3 2 Kelch motif BTB PF00651.26 EER28502.1 - 0.24 11.3 0.0 1.1 9.2 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain MFS_1 PF07690.11 EER28503.1 - 2e-21 76.1 25.2 8.1e-20 70.8 0.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER28503.1 - 3.9e-06 25.7 4.3 3.9e-06 25.7 3.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EER28503.1 - 5.7e-06 26.0 2.2 0.0037 17.0 0.1 3.3 3 0 0 3 3 3 2 MFS_1 like family Aldo_ket_red PF00248.16 EER28504.1 - 6.1e-49 166.3 0.0 8e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 EER28505.1 - 1.5e-06 27.8 4.2 8.8 6.3 0.0 7.0 8 0 0 8 8 8 2 WD domain, G-beta repeat NACHT PF05729.7 EER28505.1 - 6.3e-06 25.9 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 EER28505.1 - 1.9e-05 24.0 0.3 4.2e-05 22.9 0.2 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EER28505.1 - 0.00025 20.7 0.3 0.00058 19.5 0.2 1.5 1 0 0 1 1 1 1 PGAP1-like protein AAA_22 PF13401.1 EER28505.1 - 0.0011 19.1 0.0 0.0062 16.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain DUF829 PF05705.9 EER28505.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) AAA_14 PF13173.1 EER28505.1 - 0.057 13.3 0.1 6.2 6.7 0.1 3.3 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EER28505.1 - 0.084 12.5 0.0 0.96 9.1 0.0 2.3 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.15 EER28505.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 EER28505.1 - 0.089 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 EER28505.1 - 0.17 10.5 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Fructosamin_kin PF03881.9 EER28506.1 - 2.7e-37 128.3 0.0 4.3e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EER28506.1 - 1.1e-05 25.3 0.1 1.8e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family BLVR PF06375.6 EER28506.1 - 2.3 8.0 17.5 4.7 7.0 12.1 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) RNase_H2-Ydr279 PF09468.5 EER28506.1 - 2.8 7.0 11.4 5.4 6.1 7.9 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AhpC-TSA PF00578.16 EER28507.1 - 6.7e-28 96.8 0.0 3.3e-22 78.4 0.0 2.5 2 1 1 3 3 3 2 AhpC/TSA family 1-cysPrx_C PF10417.4 EER28507.1 - 1.6e-11 43.6 0.1 3.2e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EER28507.1 - 2.1e-10 40.3 0.0 1.4e-09 37.6 0.0 2.0 2 0 0 2 2 2 1 Redoxin MFS_1 PF07690.11 EER28508.1 - 1.7e-42 145.4 25.3 1.7e-42 145.4 17.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER28508.1 - 1.2e-08 33.6 4.8 1.9e-08 33.0 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER28508.1 - 2.7e-07 29.5 22.9 5.8e-07 28.4 15.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EER28508.1 - 0.0014 16.7 2.3 0.088 10.8 0.5 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EER28508.1 - 0.0017 16.5 1.5 0.0017 16.5 1.0 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector APH PF01636.18 EER28509.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family HTH_AsnC-type PF13404.1 EER28509.1 - 0.15 11.6 0.8 0.32 10.5 0.6 1.6 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Methyltransf_PK PF05891.7 EER28510.1 - 4.2e-75 251.7 0.0 4.8e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EER28510.1 - 3e-05 23.7 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER28510.1 - 7.7e-05 23.2 0.1 0.00013 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EER28510.1 - 0.00046 19.4 0.0 0.00059 19.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EER28510.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EER28510.1 - 0.023 15.1 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sec23_helical PF04815.10 EER28510.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Sec23/Sec24 helical domain EVE PF01878.13 EER28511.1 - 6.9e-52 175.2 0.1 1.2e-51 174.4 0.1 1.4 1 0 0 1 1 1 1 EVE domain Aldedh PF00171.17 EER28512.1 - 1.7e-182 606.9 1.4 1.9e-182 606.7 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DDE_1 PF03184.14 EER28513.1 - 4.9e-35 120.6 0.0 1.7e-34 118.8 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease Asp-B-Hydro_N PF05279.6 EER28513.1 - 0.11 12.2 17.3 0.16 11.7 12.0 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region HHA PF05321.6 EER28513.1 - 4.4 7.5 6.9 20 5.4 3.4 2.8 2 1 0 2 2 2 0 Haemolysin expression modulating protein DIOX_N PF14226.1 EER28514.1 - 9.6e-32 109.9 0.0 2.5e-31 108.5 0.0 1.8 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EER28514.1 - 4.9e-16 58.8 0.0 1.1e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YvbH_ext PF11724.3 EER28514.1 - 0.23 11.1 0.8 0.53 9.9 0.6 1.6 1 0 0 1 1 1 0 YvbH-like oligomerisation region NmrA PF05368.8 EER28515.1 - 7.6e-57 192.2 0.1 9.5e-57 191.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EER28515.1 - 1.1e-12 48.3 0.0 1.8e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EER28515.1 - 0.0036 16.0 0.0 0.0051 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2119 PF09892.4 EER28515.1 - 0.082 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) MFS_1 PF07690.11 EER28516.1 - 1.6e-44 152.0 43.0 3.1e-44 151.1 29.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily WTF PF03303.8 EER28516.1 - 0.039 13.3 5.0 0.067 12.6 3.5 1.3 1 0 0 1 1 1 0 WTF protein Fungal_trans PF04082.13 EER28517.1 - 6e-17 61.3 0.0 9.2e-17 60.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28517.1 - 7.1e-10 38.6 10.4 1.2e-09 37.9 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MARVEL PF01284.18 EER28518.1 - 7.1e-10 38.8 12.2 9.5e-10 38.4 8.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Glyco_hydro_76 PF03663.9 EER28519.1 - 2.3e-156 520.8 6.8 3e-156 520.4 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EER28519.1 - 0.0013 17.8 4.4 0.4 9.6 0.1 3.3 3 0 0 3 3 3 3 Glycosyl Hydrolase Family 88 PFK PF00365.15 EER28520.1 - 1.5e-169 562.2 0.2 5.6e-121 402.8 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 EER28520.1 - 0.039 13.4 0.5 0.11 12.0 0.4 1.7 1 0 0 1 1 1 0 UvrB/uvrC motif IBR PF01485.16 EER28521.1 - 1.4e-14 53.6 52.0 4.7e-09 35.9 4.3 4.8 4 1 0 4 4 4 3 IBR domain zf-RING_2 PF13639.1 EER28521.1 - 0.00096 18.9 5.4 0.00096 18.9 3.7 4.7 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EER28521.1 - 0.0018 18.2 5.8 0.0018 18.2 4.0 5.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EER28521.1 - 0.0026 17.4 1.7 0.0026 17.4 1.1 3.4 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EER28521.1 - 0.0055 16.3 2.4 0.0055 16.3 1.7 5.1 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EER28521.1 - 0.011 15.6 1.3 0.011 15.6 0.9 5.0 4 1 0 4 4 4 0 zinc finger of C3HC4-type, RING Med17 PF10156.4 EER28522.1 - 3e-121 404.9 0.0 3.8e-121 404.6 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex ISN1 PF06437.6 EER28523.1 - 1.6e-191 636.4 0.0 1.7e-191 636.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Ank_2 PF12796.2 EER28524.1 - 1.2e-83 275.4 19.9 4.4e-17 62.1 0.3 9.2 5 4 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 EER28524.1 - 4.4e-58 190.3 30.9 2.3e-06 27.1 0.0 16.6 18 1 1 19 19 19 12 Ankyrin repeat Ank_3 PF13606.1 EER28524.1 - 1.9e-55 179.2 11.8 3e-05 23.8 0.0 17.8 18 0 0 18 18 18 12 Ankyrin repeat Ank_4 PF13637.1 EER28524.1 - 1e-31 108.7 15.6 2.3e-07 31.1 0.0 12.7 9 4 6 15 15 15 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER28524.1 - 1.4e-31 107.7 17.3 0.0036 17.4 0.0 14.0 12 3 3 16 16 16 7 Ankyrin repeats (many copies) Clr5 PF14420.1 EER28524.1 - 3.6e-21 74.7 0.8 1.9e-20 72.4 0.1 2.4 3 0 0 3 3 3 1 Clr5 domain Shigella_OspC PF06128.6 EER28524.1 - 0.0074 15.8 0.0 9.2 5.6 0.0 4.0 4 1 1 5 5 5 1 Shigella flexneri OspC protein Prok-E2_E PF14462.1 EER28524.1 - 0.15 11.6 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family E cNMP_binding PF00027.24 EER28525.1 - 1.2e-39 133.9 0.5 1.5e-20 72.7 0.0 4.7 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EER28525.1 - 4.4e-18 65.9 7.0 7.6e-17 61.9 4.8 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase DUF2296 PF10058.4 EER28527.1 - 1.9e-19 69.1 0.1 3.2e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) GRIP PF01465.15 EER28528.1 - 2.4e-18 65.3 0.1 4.9e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 GRIP domain Reo_sigmaC PF04582.7 EER28528.1 - 1.3e-08 34.3 55.2 0.0071 15.5 6.4 6.5 4 2 3 7 7 7 5 Reovirus sigma C capsid protein IncA PF04156.9 EER28528.1 - 3.1e-08 33.4 144.5 1.5e-05 24.6 4.5 8.3 3 3 5 8 8 8 6 IncA protein Filament PF00038.16 EER28528.1 - 9.3e-08 31.8 129.6 0.0035 16.8 30.6 7.5 3 2 4 7 7 7 5 Intermediate filament protein AAA_13 PF13166.1 EER28528.1 - 1.2e-05 24.0 103.1 0.0065 14.9 11.1 5.1 3 1 2 5 5 5 4 AAA domain Myosin_tail_1 PF01576.14 EER28528.1 - 8.2e-05 20.5 150.8 0.018 12.7 14.1 5.4 3 1 2 5 5 5 3 Myosin tail Macoilin PF09726.4 EER28528.1 - 0.00041 18.7 4.3 0.00041 18.7 3.0 4.5 1 1 2 4 4 3 2 Transmembrane protein Spc7 PF08317.6 EER28528.1 - 0.00043 19.0 126.9 0.0074 14.9 5.8 8.0 3 2 4 8 8 8 7 Spc7 kinetochore protein Lzipper-MIP1 PF14389.1 EER28528.1 - 0.00047 20.1 2.6 0.00047 20.1 1.8 9.2 6 3 2 8 8 7 1 Leucine-zipper of ternary complex factor MIP1 CENP-F_leu_zip PF10473.4 EER28528.1 - 0.0013 18.5 151.1 0.0086 15.9 15.3 9.7 3 2 8 11 11 10 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EER28528.1 - 0.0016 17.0 145.2 0.072 11.5 33.7 6.5 3 2 3 6 6 6 5 Weak chloroplast movement under blue light TBPIP PF07106.8 EER28528.1 - 0.0019 17.7 116.0 0.032 13.7 0.8 10.8 3 2 8 11 11 11 3 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CASP_C PF08172.7 EER28528.1 - 0.0029 16.6 1.7 0.0029 16.6 1.2 10.5 4 2 5 10 10 7 1 CASP C terminal FliJ PF02050.11 EER28528.1 - 0.0087 16.1 16.8 0.0087 16.1 11.6 8.6 5 3 4 9 9 9 3 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 EER28528.1 - 0.011 15.5 139.4 0.025 14.3 6.3 10.0 4 2 5 9 9 8 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EER28528.1 - 0.018 14.2 134.5 0.26 10.4 3.6 9.4 4 2 4 9 9 8 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.2 EER28528.1 - 0.019 14.2 123.2 0.2 10.9 0.1 7.8 4 2 2 6 6 6 0 Mechanosensitive ion channel porin domain DivIC PF04977.10 EER28528.1 - 0.028 13.9 0.1 0.028 13.9 0.1 14.4 6 4 10 16 16 16 0 Septum formation initiator Baculo_PEP_C PF04513.7 EER28528.1 - 0.038 13.8 47.0 0.11 12.3 2.8 7.8 3 2 3 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 EER28528.1 - 0.06 12.3 133.8 0.015 14.3 5.7 7.2 3 2 5 8 8 8 0 Autophagy protein Apg6 ATG16 PF08614.6 EER28528.1 - 0.065 13.0 133.5 0.036 13.8 12.2 9.4 3 2 6 9 9 9 0 Autophagy protein 16 (ATG16) Bap31 PF05529.7 EER28528.1 - 0.21 11.0 0.0 0.21 11.0 0.0 9.8 4 4 2 6 6 4 0 B-cell receptor-associated protein 31-like DUF869 PF05911.6 EER28528.1 - 0.3 9.2 121.2 0.78 7.8 19.7 4.7 2 2 3 5 5 5 0 Plant protein of unknown function (DUF869) EzrA PF06160.7 EER28528.1 - 0.31 9.1 105.7 0.97 7.5 5.6 5.6 3 2 2 5 5 5 0 Septation ring formation regulator, EzrA DUF342 PF03961.8 EER28528.1 - 2.4 6.4 91.1 1.6 7.0 8.8 7.1 3 2 3 7 7 7 0 Protein of unknown function (DUF342) Tropomyosin_1 PF12718.2 EER28528.1 - 6.3 6.6 160.5 0.8 9.5 5.9 9.0 3 3 6 9 9 8 0 Tropomyosin like Fib_alpha PF08702.5 EER28528.1 - 7.2 6.7 84.7 5.2 7.1 11.3 9.3 3 2 8 11 11 11 0 Fibrinogen alpha/beta chain family ERM PF00769.14 EER28528.1 - 7.3 6.0 151.5 0.0096 15.4 9.7 7.5 1 1 5 7 7 7 0 Ezrin/radixin/moesin family Acetyltransf_1 PF00583.19 EER28529.1 - 1.1e-16 60.6 0.0 1.7e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EER28529.1 - 8.1e-09 35.1 0.0 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EER28529.1 - 1.5e-08 34.9 0.0 2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER28529.1 - 3e-08 33.7 0.0 4.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER28529.1 - 6.1e-06 26.3 0.0 1.1e-05 25.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER28529.1 - 0.00043 20.2 0.0 0.0044 16.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER28529.1 - 0.0049 16.7 0.0 0.17 11.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER28529.1 - 0.023 14.5 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EER28529.1 - 0.03 14.1 0.0 0.059 13.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Anoctamin PF04547.7 EER28530.1 - 3.6e-120 401.6 1.8 4.4e-120 401.3 1.2 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel UbiA PF01040.13 EER28530.1 - 8.2 5.5 16.3 6 5.9 0.4 2.8 2 1 0 2 2 2 0 UbiA prenyltransferase family bZIP_1 PF00170.16 EER28531.1 - 4.1e-07 29.8 8.7 1.3e-06 28.2 6.0 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EER28531.1 - 0.18 11.6 11.3 17 5.3 7.7 3.3 2 1 0 2 2 2 0 Basic region leucine zipper Actin PF00022.14 EER28532.1 - 4.2e-55 186.7 0.0 6e-53 179.6 0.0 2.5 1 1 0 1 1 1 1 Actin Phage_connect_1 PF05135.8 EER28532.1 - 0.057 13.5 2.1 0.14 12.3 1.4 1.6 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein YL1_C PF08265.6 EER28533.1 - 3.3e-17 61.7 0.5 7.2e-17 60.6 0.1 1.8 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain LAT PF15234.1 EER28533.1 - 0.15 11.5 2.2 0.2 11.0 1.4 1.4 1 1 0 1 1 1 0 Linker for activation of T-cells Got1 PF04178.7 EER28534.1 - 1.3e-19 70.4 14.2 1.6e-19 70.1 9.8 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF4418 PF14387.1 EER28534.1 - 0.36 10.5 2.5 1.1 8.9 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) SdpI PF13630.1 EER28534.1 - 8 6.2 13.6 8.8 6.1 2.1 2.4 2 0 0 2 2 2 0 SdpI/YhfL protein family Profilin PF00235.14 EER28535.1 - 1.9e-41 140.9 0.0 2.1e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Profilin CHASE4 PF05228.8 EER28535.1 - 0.041 13.4 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 CHASE4 domain Plant_vir_prot PF01307.12 EER28535.1 - 0.087 12.5 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Plant viral movement protein Sec63 PF02889.11 EER28537.1 - 2.5e-146 486.8 0.0 2.1e-91 306.4 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EER28537.1 - 2.6e-54 183.2 0.2 3.7e-28 98.1 0.5 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EER28537.1 - 2.6e-16 59.9 0.0 1.5e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EER28537.1 - 4.1e-16 58.6 0.0 3.1e-07 30.1 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EER28537.1 - 4e-07 30.2 0.1 0.024 14.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EER28537.1 - 4.2e-06 26.4 0.7 0.015 15.0 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 EER28537.1 - 0.00032 19.6 0.1 0.51 9.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 EER28537.1 - 0.018 14.2 0.0 2.1 7.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 EER28537.1 - 0.022 14.1 0.2 19 4.6 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EER28537.1 - 0.049 13.0 0.1 9.1 5.6 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family PHZA_PHZB PF03284.8 EER28537.1 - 0.074 12.1 0.2 0.15 11.1 0.1 1.4 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B Longin PF13774.1 EER28538.1 - 4.1e-14 51.8 0.0 8.1e-14 50.9 0.0 1.5 1 1 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EER28538.1 - 7.3e-14 51.1 0.2 1.1e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EER28538.1 - 0.037 13.8 0.3 0.079 12.7 0.2 1.5 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Ras PF00071.17 EER28541.1 - 5.8e-40 136.3 0.0 3.2e-37 127.4 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EER28541.1 - 5.8e-19 68.7 0.0 8.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EER28541.1 - 2.5e-11 43.1 0.0 4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EER28541.1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EER28541.1 - 0.00066 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EER28541.1 - 0.00078 18.7 0.1 0.0014 17.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EER28541.1 - 0.0057 16.8 0.0 0.013 15.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EER28541.1 - 0.01 15.8 0.2 0.037 14.0 0.1 2.0 2 1 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EER28541.1 - 0.013 14.9 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EER28541.1 - 0.026 13.7 0.1 0.047 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EER28541.1 - 0.032 14.1 0.0 0.072 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EER28541.1 - 0.044 13.4 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_24 PF13479.1 EER28541.1 - 0.048 13.2 0.1 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EER28541.1 - 0.052 13.5 1.1 0.087 12.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EER28541.1 - 0.052 13.4 0.4 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EER28541.1 - 0.079 12.7 0.0 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EER28541.1 - 0.11 12.1 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF3433 PF11915.3 EER28542.1 - 3.5e-46 155.2 11.2 2e-23 82.3 1.0 3.6 3 0 0 3 3 3 3 Protein of unknown function (DUF3433) AAA PF00004.24 EER28543.1 - 8.3e-16 58.3 0.0 1.6e-15 57.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EER28543.1 - 0.00055 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Zot PF05707.7 EER28543.1 - 0.0014 18.1 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 EER28543.1 - 0.0021 18.0 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EER28543.1 - 0.0037 17.3 0.5 0.022 14.8 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER28543.1 - 0.0081 15.8 1.0 0.047 13.4 0.7 2.1 1 1 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EER28543.1 - 0.013 15.2 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 EER28543.1 - 0.085 12.6 0.0 0.4 10.4 0.0 2.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_17 PF13207.1 EER28543.1 - 0.094 13.5 0.1 0.36 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EER28543.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EER28543.1 - 0.19 10.7 0.2 0.44 9.4 0.0 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Clr5 PF14420.1 EER28544.1 - 8.5e-19 67.2 5.0 8.5e-19 67.2 3.5 2.1 3 0 0 3 3 3 1 Clr5 domain TPR_12 PF13424.1 EER28544.1 - 2.2e-14 53.1 8.0 5.1e-06 26.3 0.3 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EER28544.1 - 0.00049 19.7 0.7 0.014 15.0 0.5 3.0 3 0 0 3 3 3 1 TPR repeat TPR_7 PF13176.1 EER28544.1 - 0.0071 16.0 6.0 3.9 7.5 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EER28544.1 - 0.0098 16.2 4.3 0.27 11.6 1.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EER28544.1 - 0.021 14.6 4.6 3 7.9 0.2 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EER28544.1 - 0.032 14.1 6.2 1.1 9.2 1.0 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EER28544.1 - 2.1 9.2 11.8 11 6.9 0.0 4.3 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EER28544.1 - 4.9 7.9 10.1 2.5 8.8 2.6 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat ADH_zinc_N PF00107.21 EER28545.1 - 4.5e-25 87.6 0.2 8.5e-25 86.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER28545.1 - 2.5e-21 75.5 1.0 4.5e-21 74.6 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EER28545.1 - 1e-07 32.9 0.0 3.1e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EER28545.1 - 0.0045 16.1 0.1 0.0074 15.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EER28545.1 - 0.0089 15.8 0.7 0.018 14.8 0.5 1.5 1 0 0 1 1 1 1 ThiF family IlvN PF07991.7 EER28545.1 - 0.019 14.3 0.1 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FMN_dh PF01070.13 EER28546.1 - 6.5e-120 400.2 0.0 8e-120 399.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EER28546.1 - 9.7e-23 79.7 0.0 1.7e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EER28546.1 - 2.5e-07 29.9 0.0 4.1e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EER28546.1 - 6.6e-05 22.2 0.1 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EER28546.1 - 0.00036 19.5 0.2 0.0008 18.3 0.0 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EER28546.1 - 0.095 11.9 0.2 0.4 9.8 0.1 2.0 1 1 1 2 2 2 0 Histidine biosynthesis protein Salt_tol_Pase PF09506.5 EER28546.1 - 0.18 10.3 0.0 0.31 9.5 0.0 1.3 1 0 0 1 1 1 0 Glucosylglycerol-phosphate phosphatase (Salt_tol_Pase) Bud13 PF09736.4 EER28547.1 - 1.2e-45 155.2 5.8 1.2e-45 155.2 4.0 2.9 2 1 1 3 3 3 1 Pre-mRNA-splicing factor of RES complex DUF2149 PF09919.4 EER28547.1 - 0.16 12.0 0.2 0.46 10.6 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Pkinase PF00069.20 EER28549.1 - 8.1e-41 139.8 0.0 1.9e-24 86.2 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER28549.1 - 5.6e-14 51.8 0.1 9.3e-10 37.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Metallophos PF00149.23 EER28550.1 - 2.8e-10 39.9 4.5 9e-10 38.2 2.1 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER28550.1 - 1.1e-05 25.3 0.0 2.5e-05 24.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PEP-utilisers_N PF05524.8 EER28551.1 - 0.064 13.0 0.8 0.1 12.4 0.6 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal DNA_binding_1 PF01035.15 EER28552.1 - 1.2e-20 72.9 0.3 2.4e-20 72.0 0.2 1.4 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Fungal_trans_2 PF11951.3 EER28554.1 - 1.8e-67 227.5 6.4 2.2e-67 227.3 4.5 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3176 PF11374.3 EER28554.1 - 0.17 11.7 1.6 2.6 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) NmrA PF05368.8 EER28555.1 - 2.1e-19 69.7 0.0 2.7e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EER28555.1 - 1.4e-15 57.7 0.0 3.4e-15 56.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EER28555.1 - 5.2e-09 35.5 0.0 8.9e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EER28555.1 - 1.3e-05 25.5 0.0 4.1e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EER28555.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EER28555.1 - 0.00017 21.8 0.7 0.00033 20.8 0.1 1.7 2 0 0 2 2 1 1 Putative NAD(P)-binding ThiF PF00899.16 EER28555.1 - 0.00018 21.3 0.4 0.0017 18.2 0.1 2.3 1 1 1 2 2 2 1 ThiF family ApbA PF02558.11 EER28555.1 - 0.0006 19.2 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EER28555.1 - 0.0013 18.8 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EER28555.1 - 0.0016 18.7 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EER28555.1 - 0.0035 17.2 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 EER28555.1 - 0.0057 16.1 0.1 0.1 11.9 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EER28555.1 - 0.0058 15.3 0.1 0.019 13.7 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EER28555.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 EER28555.1 - 0.053 13.4 0.4 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 3HCDH_N PF02737.13 EER28555.1 - 0.055 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EER28555.1 - 0.055 13.3 0.1 0.13 12.1 0.0 1.7 2 0 0 2 2 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EER28555.1 - 0.065 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain K_oxygenase PF13434.1 EER28555.1 - 0.081 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) XdhC_C PF13478.1 EER28555.1 - 0.083 13.1 0.0 0.82 9.9 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain Glyco_trans_4_4 PF13579.1 EER28555.1 - 0.085 12.9 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain NAD_Gly3P_dh_N PF01210.18 EER28555.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.17 EER28555.1 - 0.11 13.0 0.1 0.4 11.2 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EER28555.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Brr6_like_C_C PF10104.4 EER28556.1 - 2.9e-44 149.8 0.7 3.7e-44 149.5 0.5 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain AA_permease_2 PF13520.1 EER28557.1 - 1.1e-58 198.7 50.6 1.4e-58 198.4 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER28557.1 - 2e-08 33.0 40.3 2.9e-08 32.5 27.9 1.2 1 0 0 1 1 1 1 Amino acid permease 2-oxoacid_dh PF00198.18 EER28559.1 - 9.7e-80 267.1 0.1 1.4e-79 266.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EER28559.1 - 1.1e-16 60.2 1.1 2.2e-16 59.2 0.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EER28559.1 - 3.6e-05 23.0 5.1 0.00034 19.8 2.5 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 EER28559.1 - 0.0056 17.0 0.8 0.33 11.2 0.3 2.5 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EER28559.1 - 0.0071 15.9 0.6 0.1 12.3 0.2 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like DUF3614 PF12267.3 EER28559.1 - 0.12 12.5 2.4 2.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Complex1_LYR PF05347.10 EER28560.1 - 1.5e-08 34.2 0.9 2.4e-08 33.6 0.6 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EER28560.1 - 1.5e-06 28.3 0.5 2.5e-06 27.5 0.4 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EER28560.1 - 0.1 13.0 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Complex1_LYR-like Histone PF00125.19 EER28561.1 - 8.2e-26 89.9 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EER28561.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EER28562.1 - 9.5e-22 76.9 0.2 1.4e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EER28562.1 - 7.2e-05 22.7 1.0 0.0001 22.2 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EER28562.1 - 0.00022 21.4 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EER28562.1 - 0.009 15.4 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF1018 PF06252.7 EER28562.1 - 0.016 15.7 0.3 0.023 15.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Peptidase_C54 PF03416.14 EER28563.1 - 2e-93 312.5 0.0 2.4e-93 312.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 YccV-like PF08755.6 EER28565.1 - 1.6e-27 95.3 0.2 3.8e-27 94.1 0.1 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EER28565.1 - 2.4e-13 49.8 0.0 4.2e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EER28565.1 - 0.00042 19.9 0.1 0.0034 17.0 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EER28565.1 - 0.0095 15.5 0.2 0.059 13.0 0.1 2.2 2 0 0 2 2 2 1 F-box domain Peptidase_C12 PF01088.16 EER28566.1 - 8.2e-61 204.8 0.4 1.6e-60 203.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Unstab_antitox PF09720.5 EER28566.1 - 0.22 11.2 1.8 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Putative addiction module component HNH_2 PF13391.1 EER28567.1 - 1.2e-09 37.7 0.0 3e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease ERO1 PF04137.10 EER28568.1 - 2.4e-134 447.8 0.0 3.6e-134 447.3 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Methyltransf_28 PF02636.12 EER28569.1 - 1e-34 120.0 0.0 1.3e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Tim17 PF02466.14 EER28570.1 - 7.9e-25 87.3 0.4 1.1e-24 86.8 0.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Brix PF04427.13 EER28571.1 - 5.9e-28 97.8 0.0 8.2e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain RNase_P_p30 PF01876.11 EER28573.1 - 2.5e-51 172.8 0.0 3.5e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.20 EER28574.1 - 2.5e-58 197.3 0.0 2.9e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER28574.1 - 1.3e-19 70.3 0.0 1.9e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER28574.1 - 4.8e-08 33.0 0.1 0.00017 21.4 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER28574.1 - 0.013 15.1 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EER28574.1 - 0.016 14.1 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EER28574.1 - 0.056 12.5 0.1 0.099 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_1 PF00133.17 EER28575.1 - 2.6e-212 706.0 0.7 1.4e-211 703.6 0.5 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EER28575.1 - 7.4e-35 119.9 0.9 7.4e-35 119.9 0.6 2.3 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EER28575.1 - 2.7e-17 62.5 1.3 7.2e-08 31.4 0.1 5.1 3 2 1 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EER28575.1 - 2.1e-08 33.7 5.0 8.5e-05 21.9 0.0 3.4 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EER28575.1 - 0.032 13.3 0.0 0.49 9.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF4659 PF15558.1 EER28576.1 - 0.099 11.2 0.6 0.15 10.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) Grp1_Fun34_YaaH PF01184.14 EER28577.1 - 1.7e-23 83.0 17.1 2.1e-23 82.7 11.9 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family zf-rbx1 PF12678.2 EER28578.1 - 6e-11 42.2 2.3 1.3e-10 41.2 1.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EER28578.1 - 2.5e-09 36.8 9.2 2.5e-08 33.6 6.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EER28578.1 - 1.2e-07 31.2 0.5 2.7e-07 30.1 0.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER28578.1 - 1.9e-07 30.6 4.1 1.7e-06 27.6 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER28578.1 - 6.8e-06 26.0 2.1 6.8e-06 26.0 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER28578.1 - 0.00016 21.3 3.5 0.00091 18.9 2.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EER28578.1 - 0.00057 19.5 2.5 0.0019 17.8 1.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EER28578.1 - 0.029 14.2 5.7 0.42 10.4 3.9 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EER28578.1 - 0.05 13.4 1.1 0.11 12.3 0.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Transposase_28 PF04195.7 EER28578.1 - 0.057 12.7 0.1 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative gypsy type transposon zf-RING_4 PF14570.1 EER28578.1 - 1.1 8.9 4.0 0.38 10.3 0.8 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain ATP_transf PF09830.4 EER28580.1 - 1.1e-19 70.0 0.0 1.9e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase GalP_UDP_transf PF01087.17 EER28580.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain zf-C2H2_4 PF13894.1 EER28581.1 - 0.00021 21.3 17.3 0.095 13.0 0.0 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EER28581.1 - 0.0007 19.7 20.3 0.79 10.1 0.0 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EER28581.1 - 0.012 15.4 1.3 0.6 10.0 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Peroxin-13_N PF04088.8 EER28582.1 - 1.3e-61 207.1 0.4 2.1e-61 206.4 0.3 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EER28582.1 - 2.4e-07 30.1 0.0 4.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EER28582.1 - 7.2e-07 28.4 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EER28582.1 - 1.8e-06 27.4 0.1 2.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_S8 PF00082.17 EER28583.1 - 0.00089 18.4 0.2 0.00096 18.3 0.1 1.0 1 0 0 1 1 1 1 Subtilase family Ureidogly_hydro PF04115.7 EER28584.1 - 3.1e-49 166.4 0.0 4e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate hydrolase MutS_V PF00488.16 EER28585.1 - 2.1e-85 285.8 0.0 3.4e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EER28585.1 - 1e-37 129.8 9.4 1.3e-37 129.5 5.9 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EER28585.1 - 3.7e-21 75.2 0.0 1.1e-20 73.7 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EER28585.1 - 2.7e-08 33.9 0.0 1e-07 32.0 0.0 1.9 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EER28585.1 - 0.00049 20.2 0.0 0.0015 18.6 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV DUF3405 PF11885.3 EER28585.1 - 0.0063 14.8 0.1 0.0097 14.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) AAA_29 PF13555.1 EER28585.1 - 0.035 13.6 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EER28585.1 - 0.19 12.0 2.4 0.67 10.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain HALZ PF02183.13 EER28585.1 - 1.3 8.8 6.2 7 6.4 0.3 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper Sec63 PF02889.11 EER28586.1 - 9.9e-194 642.5 0.0 6.9e-106 354.0 0.0 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EER28586.1 - 1.2e-53 181.0 0.7 2.6e-31 108.3 0.0 4.0 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EER28586.1 - 3.5e-16 59.5 0.0 6.3e-08 32.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EER28586.1 - 4.7e-12 45.5 0.0 8.6e-10 38.3 0.0 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EER28586.1 - 3.3e-07 30.4 0.2 0.0011 19.0 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EER28586.1 - 0.00014 21.4 0.2 0.46 9.8 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain T2SE PF00437.15 EER28586.1 - 0.00047 19.1 0.0 0.44 9.3 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.11 EER28586.1 - 0.0026 17.0 0.0 0.51 9.5 0.0 2.8 3 0 0 3 3 3 1 PhoH-like protein AAA_19 PF13245.1 EER28586.1 - 0.021 14.5 0.0 2.1 8.1 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain Peptidase_S9 PF00326.16 EER28587.1 - 3.9e-50 170.0 0.3 8.9e-50 168.8 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EER28587.1 - 1.7e-08 34.2 0.0 3.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER28587.1 - 1.2e-06 28.5 1.2 1.2e-06 28.5 0.8 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family AXE1 PF05448.7 EER28587.1 - 0.00096 17.7 0.0 0.03 12.8 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EER28587.1 - 0.018 14.4 0.1 0.064 12.6 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Pkinase PF00069.20 EER28588.1 - 2.9e-27 95.4 0.0 6.7e-17 61.4 0.0 2.4 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER28588.1 - 2.7e-12 46.3 0.1 2.2e-07 30.2 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase CAP_GLY PF01302.20 EER28589.1 - 5.7e-15 54.7 2.0 1.3e-14 53.6 1.4 1.6 1 0 0 1 1 1 1 CAP-Gly domain Peptidase_S46 PF10459.4 EER28589.1 - 0.022 13.1 15.5 0.032 12.6 10.8 1.1 1 0 0 1 1 1 0 Peptidase S46 Reo_sigmaC PF04582.7 EER28589.1 - 0.059 12.5 3.5 0.29 10.2 0.1 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Spc7 PF08317.6 EER28589.1 - 0.083 11.5 23.9 0.022 13.4 4.0 3.0 1 1 1 3 3 3 0 Spc7 kinetochore protein DUF1664 PF07889.7 EER28589.1 - 0.26 11.0 14.2 0.74 9.6 1.2 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EER28589.1 - 0.27 11.5 6.4 25 5.2 0.2 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 EER28589.1 - 0.41 9.9 3.5 1.1 8.5 1.9 2.0 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) AAA_13 PF13166.1 EER28589.1 - 0.63 8.4 18.1 6.9 4.9 12.4 2.1 1 1 0 1 1 1 0 AAA domain ATG16 PF08614.6 EER28589.1 - 0.73 9.6 28.9 0.93 9.2 4.0 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF745 PF05335.8 EER28589.1 - 3.9 6.9 11.7 0.12 11.8 3.1 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF745) Cortex-I_coil PF09304.5 EER28589.1 - 4.1 7.5 29.1 2.6 8.1 7.0 3.4 2 1 1 3 3 3 0 Cortexillin I, coiled coil WEMBL PF05701.6 EER28589.1 - 7.2 4.9 31.0 7.5 4.8 17.0 2.5 2 1 0 2 2 2 0 Weak chloroplast movement under blue light DUF3584 PF12128.3 EER28589.1 - 7.4 3.7 28.9 12 3.0 5.2 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) 3-HAO PF06052.7 EER28590.1 - 2.5e-52 176.2 0.0 3.5e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EER28590.1 - 0.00038 19.8 0.0 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EER28590.1 - 0.0045 16.6 0.4 0.013 15.2 0.1 1.8 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EER28590.1 - 0.013 14.9 0.2 0.03 13.7 0.0 1.6 2 0 0 2 2 2 0 Cupin DZR PF12773.2 EER28590.1 - 0.075 12.8 1.4 0.19 11.5 0.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EER28590.1 - 0.34 10.8 3.3 0.51 10.3 0.4 2.3 2 0 0 2 2 2 0 Zinc ribbon domain RTC_insert PF05189.8 EER28591.1 - 3.1e-31 107.4 0.0 5.9e-31 106.5 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 EER28591.1 - 9.6e-30 103.0 0.0 1.4e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PWWP PF00855.12 EER28592.1 - 6.4e-15 55.1 3.6 5.1e-14 52.2 2.5 2.5 1 1 0 1 1 1 1 PWWP domain PAP2_3 PF14378.1 EER28593.1 - 2.5e-19 69.5 18.1 1.6e-10 40.8 0.3 3.9 4 1 0 4 4 4 3 PAP2 superfamily Nse5 PF08691.5 EER28593.1 - 0.046 12.2 0.1 0.071 11.6 0.1 1.2 1 0 0 1 1 1 0 DNA repair proteins Nse5 and Nse6 Pro-kuma_activ PF09286.6 EER28595.1 - 3.3e-37 127.6 0.0 6.9e-37 126.6 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EER28595.1 - 3.3e-09 36.2 0.2 6.2e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Subtilase family ComA PF02679.10 EER28596.1 - 6.8e-58 195.5 0.0 8.9e-58 195.1 0.0 1.1 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) Pirin PF02678.11 EER28596.1 - 1.8e-32 111.3 0.1 3.6e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EER28596.1 - 1.4e-22 79.7 0.0 4.7e-22 78.0 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EER28596.1 - 9.8e-06 24.9 0.7 0.00025 20.5 0.6 2.5 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EER28596.1 - 0.11 11.9 0.1 2.7 7.4 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF861) PRKCSH PF07915.8 EER28597.1 - 1.8e-18 67.1 0.6 4.8e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EER28597.1 - 0.0036 16.7 0.0 0.022 14.2 0.0 2.1 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein RNase_H2-Ydr279 PF09468.5 EER28597.1 - 1.7 7.7 6.2 2.7 7.1 4.3 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) SH3_1 PF00018.23 EER28598.1 - 2e-37 126.3 5.9 1.1e-13 50.3 0.1 4.2 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 EER28598.1 - 7.9e-36 121.5 0.0 1.4e-35 120.7 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 EER28598.1 - 3.6e-32 109.6 6.9 3.6e-12 45.6 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EER28598.1 - 7.5e-21 73.3 0.1 1.3e-06 27.7 0.0 4.4 4 0 0 4 4 4 3 Variant SH3 domain DUF1720 PF08226.6 EER28598.1 - 0.0027 17.7 22.7 0.0027 17.7 15.8 6.0 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) SH3_3 PF08239.6 EER28598.1 - 0.0048 17.0 2.8 0.51 10.5 0.1 3.3 3 0 0 3 3 3 1 Bacterial SH3 domain SAM_1 PF00536.25 EER28598.1 - 0.018 15.2 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) HSCB_C PF07743.8 EER28600.1 - 3.3e-18 65.8 0.0 1.6e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EER28600.1 - 7.8e-10 38.3 0.0 1.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain 2-Hacid_dh_C PF02826.14 EER28601.1 - 6e-55 185.1 0.1 8e-55 184.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER28601.1 - 1.7e-26 92.2 0.1 1.9e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EER28601.1 - 1.1e-06 28.6 0.2 2.4e-06 27.4 0.1 1.6 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EER28601.1 - 0.00033 20.5 0.0 0.0006 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EER28601.1 - 0.0023 17.2 0.0 0.0063 15.9 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EER28601.1 - 0.017 15.3 0.1 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_N PF05222.10 EER28601.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, N-terminal domain F420_oxidored PF03807.12 EER28601.1 - 0.052 13.9 0.1 0.2 12.0 0.1 2.1 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EER28601.1 - 0.067 12.8 0.2 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F-box PF00646.28 EER28603.1 - 1.8e-05 24.2 3.4 5e-05 22.8 2.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER28603.1 - 0.00014 21.5 2.9 0.00033 20.3 2.0 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EER28604.1 - 4.1e-50 165.9 17.2 1.4e-10 40.6 0.2 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EER28604.1 - 8.2e-14 50.5 1.9 1.4e-13 49.7 1.3 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ribosomal_60s PF00428.14 EER28604.1 - 0.11 12.9 7.6 0.27 11.6 5.3 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Nop53 PF07767.6 EER28604.1 - 0.54 9.1 9.3 0.78 8.6 6.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SpoIIE PF07228.7 EER28605.1 - 5.6e-12 45.7 0.2 3.2e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EER28605.1 - 7.7e-11 41.8 0.1 1.7e-10 40.6 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EER28605.1 - 2.5e-05 23.7 0.1 0.026 13.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PMT PF02366.13 EER28606.1 - 6.3e-81 271.3 18.5 1.1e-80 270.5 12.8 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EER28606.1 - 8.2e-19 67.8 2.8 3.9e-16 59.1 0.2 2.2 1 1 0 2 2 2 2 MIR domain PMT_2 PF13231.1 EER28606.1 - 0.006 16.5 9.8 0.006 16.5 6.8 3.0 4 1 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MFS_1 PF07690.11 EER28608.1 - 2.8e-27 95.3 30.9 4.6e-27 94.6 21.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EER28609.1 - 1.9e-17 62.4 10.1 6.1e-05 22.7 0.1 6.9 6 2 0 6 6 6 4 WD domain, G-beta repeat PCI_Csn8 PF10075.4 EER28610.1 - 1.9e-24 86.0 0.0 2.9e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EER28610.1 - 9e-06 25.3 0.1 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family STT3 PF02516.9 EER28611.1 - 5.6e-131 437.8 41.7 3.2e-126 422.1 26.9 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.4 EER28611.1 - 0.015 13.5 0.1 0.015 13.5 0.0 2.1 2 0 0 2 2 2 0 Q-cell neuroblast polarisation DUF3453 PF11935.3 EER28612.1 - 9.3e-83 277.2 0.4 1.7e-82 276.4 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Sds3 PF08598.6 EER28613.1 - 6e-26 91.2 5.5 6e-26 91.2 3.8 3.6 3 1 0 3 3 3 1 Sds3-like RRM_1 PF00076.17 EER28614.1 - 1.9e-14 53.0 0.2 2.3e-09 36.7 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER28614.1 - 2.9e-09 36.7 0.0 7e-06 25.9 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER28614.1 - 3.1e-07 30.1 0.0 0.02 14.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ycf1 PF05758.7 EER28614.1 - 0.74 7.4 13.0 0.99 7.0 9.0 1.2 1 0 0 1 1 1 0 Ycf1 PLRV_ORF5 PF01690.12 EER28614.1 - 1 8.4 20.2 2 7.4 14.0 1.5 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MIP-T3 PF10243.4 EER28614.1 - 1.4 7.2 44.0 0.0086 14.5 22.8 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 GPI-anchored PF10342.4 EER28615.1 - 3.9e-20 72.1 1.0 3.9e-20 72.1 0.7 2.9 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family NUFIP1 PF10453.4 EER28616.1 - 1.4e-12 46.8 6.7 1.4e-12 46.8 4.6 2.7 1 1 1 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EER28616.1 - 3.1e-06 26.7 1.7 5.2e-06 26.0 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Macoilin PF09726.4 EER28616.1 - 1.6 6.9 19.1 0.019 13.3 3.9 2.1 2 0 0 2 2 2 0 Transmembrane protein RNA_pol_Rbc25 PF08292.7 EER28617.1 - 5.7e-37 126.6 0.0 6.8e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.18 EER28617.1 - 0.028 14.4 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 S1 RNA binding domain Cys_Met_Meta_PP PF01053.15 EER28618.1 - 5.6e-141 469.2 0.0 6.4e-141 469.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EER28618.1 - 8.6e-08 31.5 0.1 1.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EER28618.1 - 1.3e-06 27.7 0.2 2.3e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EER28618.1 - 2e-05 23.5 0.5 3.1e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EER28618.1 - 0.00019 20.6 0.1 0.00039 19.6 0.1 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Filament PF00038.16 EER28621.1 - 0.0017 17.9 59.1 0.0017 17.9 40.9 4.2 3 1 2 5 5 5 2 Intermediate filament protein Reo_sigmaC PF04582.7 EER28621.1 - 0.006 15.8 30.4 0.12 11.5 2.9 4.6 2 2 3 5 5 5 3 Reovirus sigma C capsid protein VirB3 PF05101.8 EER28621.1 - 0.23 11.4 0.3 0.4 10.6 0.2 1.3 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein DASH_Dam1 PF08653.5 EER28621.1 - 8.2 6.2 18.1 5.9 6.7 0.1 5.9 3 1 3 6 6 6 0 DASH complex subunit Dam1 zf-C2H2 PF00096.21 EER28622.1 - 0.0012 19.0 21.1 0.35 11.3 0.2 4.9 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER28623.1 - 7.2e-08 32.2 32.2 0.2 12.0 0.1 7.3 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 EER28623.1 - 9e-08 32.0 31.7 0.017 15.3 0.1 6.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EER28623.1 - 0.11 12.7 17.2 3.5 8.0 0.0 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EER28623.1 - 0.13 12.3 6.0 0.43 10.7 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EER28623.1 - 0.78 10.0 5.5 4.6 7.5 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Carb_kinase PF01256.12 EER28624.1 - 6.1e-47 159.9 0.0 1.3e-44 152.2 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate kinase SPT2 PF08243.6 EER28625.1 - 4.1e-09 36.7 14.5 9.1e-09 35.6 10.0 1.6 1 0 0 1 1 1 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 EER28626.1 - 5.4e-28 97.2 11.7 6.8e-28 96.9 8.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rnk_N PF14760.1 EER28626.1 - 0.17 11.9 2.0 0.42 10.7 1.4 1.7 1 0 0 1 1 1 0 Rnk N-terminus Ribosomal_S19 PF00203.16 EER28627.1 - 1e-34 117.9 0.4 1.5e-34 117.4 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SET PF00856.23 EER28629.1 - 7.9e-13 49.0 0.0 3.7e-12 46.8 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EER28629.1 - 7.7e-10 38.4 7.7 7.7e-10 38.4 5.4 2.0 2 0 0 2 2 2 1 MYND finger CPSase_L_D2 PF02786.12 EER28630.1 - 1.1e-106 354.8 0.0 4.4e-83 277.7 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EER28630.1 - 8.4e-42 141.8 0.0 2.5e-41 140.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EER28630.1 - 1.3e-37 129.3 0.2 2.8e-21 76.0 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 EER28630.1 - 1.2e-36 125.1 0.0 5.9e-18 64.9 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EER28630.1 - 6.9e-26 90.7 0.0 1.5e-10 40.3 0.0 4.2 4 1 0 4 4 4 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EER28630.1 - 4.1e-19 68.5 0.0 3.9e-08 32.8 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EER28630.1 - 6.7e-15 55.0 0.2 3.9e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EER28630.1 - 1.6e-07 30.9 0.0 0.00054 19.4 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EER28630.1 - 1.1e-05 25.3 0.0 0.058 13.2 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 EER28630.1 - 0.00011 21.8 0.1 0.12 11.9 0.0 2.5 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EER28630.1 - 0.00011 21.4 0.2 0.02 14.1 0.0 3.0 3 0 0 3 3 3 1 ATP-grasp domain Uds1 PF15456.1 EER28631.1 - 9.8 6.1 10.3 0.87 9.5 0.3 3.1 3 0 0 3 3 3 0 Up-regulated During Septation APH PF01636.18 EER28632.1 - 4e-05 23.4 0.0 0.00011 22.0 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER28632.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF4187 PF13821.1 EER28634.1 - 1e-19 69.8 1.3 3.3e-19 68.2 0.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EER28634.1 - 4.4e-10 39.1 0.3 2.3e-09 36.8 0.2 2.1 1 1 0 1 1 1 1 G-patch domain PALP PF00291.20 EER28635.1 - 8.4e-30 104.0 0.1 1.1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EER28635.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 LytB protein COesterase PF00135.23 EER28636.1 - 1.1e-93 314.8 0.0 1.4e-93 314.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EER28636.1 - 1.1e-06 28.4 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EER28636.1 - 4.8e-05 22.6 0.0 7.6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EER28636.1 - 0.0057 16.4 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EER28636.1 - 0.0093 14.8 0.0 0.076 11.8 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EER28636.1 - 0.022 14.6 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EER28636.1 - 0.073 12.4 0.1 0.46 9.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) TPR_12 PF13424.1 EER28637.1 - 6e-69 227.9 47.6 4.7e-15 55.2 0.0 6.1 2 1 6 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.1 EER28637.1 - 2.7e-40 135.1 21.8 2.7e-06 27.1 0.1 8.8 8 0 0 8 8 8 7 Tetratricopeptide repeat NB-ARC PF00931.17 EER28637.1 - 6.9e-18 64.5 0.0 1.2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 EER28637.1 - 8.8e-18 62.7 19.7 0.015 15.1 0.6 9.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 EER28637.1 - 1.4e-16 59.3 22.0 0.00073 19.0 0.0 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EER28637.1 - 9.9e-15 53.9 11.8 0.00081 18.9 0.0 5.7 4 1 0 5 5 5 3 TPR repeat TPR_16 PF13432.1 EER28637.1 - 7.7e-14 51.9 15.7 5.8e-05 23.6 0.8 6.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EER28637.1 - 2.3e-12 46.3 21.3 0.15 12.7 0.3 9.0 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.1 EER28637.1 - 1.4e-10 40.1 17.0 0.045 13.5 0.0 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat Patatin PF01734.17 EER28637.1 - 5.5e-08 32.9 1.3 2.6e-07 30.7 0.1 2.4 2 0 0 2 2 2 1 Patatin-like phospholipase TPR_19 PF14559.1 EER28637.1 - 1e-07 32.1 21.8 0.28 11.5 2.8 6.8 4 2 1 6 6 6 3 Tetratricopeptide repeat TPR_4 PF07721.9 EER28637.1 - 3.9e-07 29.8 11.7 2.2 8.9 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EER28637.1 - 1.6e-06 27.8 11.8 2 8.8 0.0 8.0 8 0 0 8 8 7 1 Tetratricopeptide repeat 14-3-3 PF00244.15 EER28637.1 - 7.5e-05 21.9 0.4 0.013 14.5 0.0 2.5 2 0 0 2 2 2 1 14-3-3 protein TPR_8 PF13181.1 EER28637.1 - 7.8e-05 22.1 21.1 2.4 8.1 0.0 8.5 9 0 0 9 9 9 1 Tetratricopeptide repeat AAA_16 PF13191.1 EER28637.1 - 0.00011 22.2 3.3 0.00013 21.9 0.6 2.6 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EER28637.1 - 0.00012 21.8 0.1 0.00035 20.3 0.1 1.8 1 0 0 1 1 1 1 Archaeal ATPase TPR_3 PF07720.7 EER28637.1 - 0.00017 21.2 1.1 0.12 12.1 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat NAGLU PF05089.7 EER28637.1 - 0.0015 17.3 0.2 1.4 7.6 0.1 3.1 2 1 1 3 3 3 2 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain AAA_14 PF13173.1 EER28637.1 - 0.0083 16.0 0.0 0.029 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_6 PF13174.1 EER28637.1 - 0.12 12.9 24.7 15 6.3 0.0 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat Pkinase PF00069.20 EER28638.1 - 2.5e-11 43.2 0.0 1e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER28638.1 - 0.002 17.2 0.1 0.008 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Fungal_trans PF04082.13 EER28639.1 - 2.4e-11 43.0 0.6 2.4e-11 43.0 0.4 2.5 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28639.1 - 5.3e-08 32.6 12.7 1.1e-07 31.5 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop14 PF04147.7 EER28640.1 - 3.3e-276 918.5 19.3 3.9e-276 918.2 13.4 1.0 1 0 0 1 1 1 1 Nop14-like family HEAT_2 PF13646.1 EER28641.1 - 0.0035 17.5 1.7 0.0035 17.5 1.2 2.0 2 0 0 2 2 2 1 HEAT repeats ORC3_N PF07034.6 EER28643.1 - 2.6e-15 56.2 0.0 8.7e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus PPR_3 PF13812.1 EER28644.1 - 4.2e-09 35.9 0.2 0.018 15.2 0.0 6.3 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EER28644.1 - 4.6e-07 29.7 0.9 0.032 14.1 0.0 4.8 5 1 1 6 6 6 2 PPR repeat family Glyco_transf_64 PF09258.5 EER28644.1 - 0.013 14.6 0.0 0.029 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain PPR PF01535.15 EER28644.1 - 0.036 14.0 0.1 4.7 7.4 0.0 3.5 3 0 0 3 3 3 0 PPR repeat DUF342 PF03961.8 EER28644.1 - 1.4 7.1 2.9 2.2 6.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sec66 PF09802.4 EER28645.1 - 1.1e-81 272.8 0.1 1.3e-81 272.5 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF1049 PF06305.6 EER28645.1 - 1.2 8.6 5.0 0.18 11.2 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) AAA PF00004.24 EER28646.1 - 3.1e-51 173.0 0.0 2.1e-42 144.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EER28646.1 - 1.3e-07 31.2 0.0 5.3e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EER28646.1 - 1.7e-06 28.1 4.8 2.2e-05 24.5 0.0 4.2 5 0 0 5 5 3 1 AAA ATPase domain AAA_2 PF07724.9 EER28646.1 - 5e-06 26.5 0.0 1.7e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EER28646.1 - 9.1e-06 25.3 0.6 0.021 14.5 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain Bromodomain PF00439.20 EER28646.1 - 0.00012 21.8 0.0 0.00033 20.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.1 EER28646.1 - 0.00016 21.8 0.1 0.0033 17.5 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER28646.1 - 0.00016 21.3 0.1 0.001 18.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EER28646.1 - 0.00043 20.3 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EER28646.1 - 0.00053 19.4 0.0 0.0019 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER28646.1 - 0.00083 19.2 0.0 0.021 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EER28646.1 - 0.0011 18.8 0.0 0.0056 16.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 EER28646.1 - 0.0015 18.6 0.0 0.0042 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.7 EER28646.1 - 0.002 17.1 0.0 0.06 12.3 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EER28646.1 - 0.0048 17.7 2.8 0.026 15.3 0.0 3.5 4 0 0 4 4 3 1 AAA domain TIP49 PF06068.8 EER28646.1 - 0.0056 15.4 0.0 0.015 14.0 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 EER28646.1 - 0.013 14.7 0.0 0.071 12.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EER28646.1 - 0.013 15.1 0.0 0.16 11.5 0.0 2.6 2 1 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 EER28646.1 - 0.027 13.9 0.0 1.7 8.0 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain ABC_tran PF00005.22 EER28646.1 - 0.033 14.4 1.7 0.12 12.6 0.0 2.9 3 0 0 3 3 1 0 ABC transporter PhoH PF02562.11 EER28646.1 - 0.04 13.1 0.0 0.089 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_3 PF07726.6 EER28646.1 - 0.046 13.3 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 EER28646.1 - 0.078 11.8 0.0 0.2 10.4 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EER28646.1 - 0.2 11.5 0.0 1.3 8.9 0.0 2.1 2 0 0 2 2 2 0 Torsin TFIIF_alpha PF05793.7 EER28646.1 - 7.4 4.8 60.6 1.4 7.1 18.7 2.4 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CPSF_A PF03178.10 EER28647.1 - 5.5e-105 351.0 0.0 1.4e-104 349.7 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EER28647.1 - 0.00015 20.0 0.0 0.13 10.3 0.0 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.11 EER28648.1 - 2.1e-09 36.5 21.8 1.4e-08 33.8 6.3 2.2 1 1 0 2 2 2 2 LMBR1-like membrane protein DUF1056 PF06341.6 EER28648.1 - 0.14 12.2 0.1 0.14 12.2 0.1 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF1056) zf-FPG_IleRS PF06827.9 EER28649.1 - 0.02 14.5 1.5 4.2 7.1 0.6 2.7 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS zf-B_box PF00643.19 EER28649.1 - 3.2 7.7 9.4 0.88 9.5 3.6 2.0 2 0 0 2 2 2 0 B-box zinc finger DUF1509 PF07420.6 EER28650.1 - 0.043 13.0 4.6 0.052 12.8 3.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1509) DUF1183 PF06682.7 EER28650.1 - 0.057 13.0 1.7 0.087 12.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) RhoGEF PF00621.15 EER28650.1 - 0.069 13.0 0.5 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 RhoGEF domain Troponin PF00992.15 EER28650.1 - 0.13 12.3 2.5 0.15 12.0 0.1 1.9 1 1 0 2 2 2 0 Troponin Atg14 PF10186.4 EER28651.1 - 3.1e-101 338.3 0.0 3.7e-101 338.0 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EER28651.1 - 0.0048 15.6 4.6 0.007 15.0 3.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ATP-cone PF03477.11 EER28651.1 - 0.01 16.2 0.8 0.024 15.0 0.6 1.6 1 0 0 1 1 1 0 ATP cone domain Alb1 PF09135.6 EER28651.1 - 0.22 12.1 10.7 0.54 10.8 7.4 1.7 1 0 0 1 1 1 0 Alb1 Mnd1 PF03962.10 EER28651.1 - 2 8.0 7.7 3.4 7.2 5.3 1.3 1 0 0 1 1 1 0 Mnd1 family DUF2401 PF10287.4 EER28652.1 - 7.3e-88 294.0 0.0 1.1e-87 293.3 0.0 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EER28652.1 - 1.5e-23 82.6 0.0 4.2e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Zip PF02535.17 EER28654.1 - 1.9e-49 168.4 2.5 2.5e-49 168.0 1.7 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Thiolase_N PF00108.18 EER28655.1 - 7.4e-97 323.4 0.0 9.9e-97 323.0 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EER28655.1 - 3.5e-44 149.1 1.1 8.3e-44 147.9 0.7 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EER28655.1 - 1e-05 25.1 0.3 2.5e-05 23.9 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EER28655.1 - 0.013 15.1 0.5 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 EER28656.1 - 2e-42 144.7 0.0 2.9e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EER28656.1 - 5.4e-26 90.5 0.0 1.5e-25 89.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EER28656.1 - 1.7e-18 66.2 0.0 5e-18 64.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EER28656.1 - 1.8e-09 37.6 0.0 5.1e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EER28656.1 - 3.6e-07 29.9 0.1 9.6e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EER28656.1 - 5.5e-06 26.3 0.1 1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER28656.1 - 0.00035 21.0 0.1 0.00081 19.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EER28656.1 - 0.11 11.9 0.0 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 Ras family DUF59 PF01883.14 EER28657.1 - 2.6e-07 30.5 0.0 4.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Fungal_trans PF04082.13 EER28658.1 - 2.5e-16 59.3 0.1 5.9e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28658.1 - 0.00023 20.9 8.4 0.00023 20.9 5.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APC_CDC26 PF10471.4 EER28659.1 - 9e-22 77.6 2.2 1e-21 77.4 1.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 BNR_3 PF13859.1 EER28659.1 - 0.11 11.5 0.1 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 BNR repeat-like domain RRF PF01765.14 EER28661.1 - 4e-38 130.4 2.8 5.1e-38 130.1 2.0 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Sterol_MT_C PF08498.5 EER28661.1 - 0.13 12.1 0.8 6.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal Metal_resist PF13801.1 EER28661.1 - 0.17 11.8 2.8 0.45 10.5 1.9 1.7 1 0 0 1 1 1 0 Heavy-metal resistance DUF4175 PF13779.1 EER28661.1 - 0.37 8.4 8.1 0.13 9.9 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4175) Herpes_UL25 PF01499.11 EER28661.1 - 1.1 7.4 4.1 1.5 7.0 2.8 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF1664 PF07889.7 EER28661.1 - 1.5 8.6 4.5 4.5 7.0 2.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3391 PF11871.3 EER28661.1 - 2.3 8.4 8.1 3 8.0 1.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3391) HSP70 PF00012.15 EER28662.1 - 7.1e-234 777.2 8.4 8e-234 777.0 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EER28662.1 - 3e-16 58.9 0.1 2.5e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EER28662.1 - 0.00049 19.7 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Bromodomain PF00439.20 EER28663.1 - 4.5e-32 109.8 1.6 1e-16 60.5 0.0 2.9 3 0 0 3 3 3 2 Bromodomain CKS PF01111.14 EER28664.1 - 4.9e-33 112.7 0.8 4.9e-33 112.7 0.6 1.5 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.1 EER28665.1 - 2.7e-07 30.7 0.0 7.1e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EER28665.1 - 0.23 10.9 3.5 0.5 9.8 0.5 2.4 2 1 1 3 3 3 0 DSBA-like thioredoxin domain TPPK_C PF12555.3 EER28666.1 - 0.12 12.0 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal DUF3844 PF12955.2 EER28667.1 - 1.2e-38 131.3 2.0 1.7e-38 130.8 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.8 EER28667.1 - 2 8.6 8.6 5.3 7.2 6.0 1.7 1 0 0 1 1 1 0 EGF-like domain zf-RING_2 PF13639.1 EER28668.1 - 1.3e-14 53.6 6.0 2e-14 53.1 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EER28668.1 - 4.4e-08 32.6 3.0 6.9e-08 32.0 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EER28668.1 - 5.4e-08 32.8 2.0 1.1e-07 31.8 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EER28668.1 - 1.9e-06 27.4 3.3 3e-06 26.8 2.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EER28668.1 - 4.3e-06 26.6 4.8 6.9e-06 25.9 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER28668.1 - 1.1e-05 25.0 1.9 1.7e-05 24.4 1.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EER28668.1 - 0.0012 18.6 2.4 0.0028 17.4 1.7 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EER28668.1 - 0.015 14.9 5.9 0.024 14.2 4.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EER28668.1 - 0.039 13.6 5.2 0.071 12.8 3.6 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EER28668.1 - 0.042 13.9 5.1 0.075 13.0 3.5 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EER28668.1 - 0.089 12.7 3.7 0.25 11.3 2.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EER28668.1 - 0.09 12.5 2.3 0.18 11.5 1.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EER28668.1 - 0.29 11.0 4.6 0.64 9.9 3.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.1 EER28668.1 - 4.3 7.1 7.7 4.5 7.0 3.3 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 p450 PF00067.17 EER28669.1 - 1.3e-47 162.4 0.0 1.6e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arena_RNA_pol PF06317.6 EER28669.1 - 0.1 9.1 0.0 0.14 8.7 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase MFS_1 PF07690.11 EER28670.1 - 6.3e-31 107.3 30.1 6.3e-31 107.3 20.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER28670.1 - 0.00086 17.9 24.8 0.0036 15.9 5.1 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EER28670.1 - 0.027 14.2 3.7 0.15 11.9 0.2 3.2 3 1 0 3 3 3 0 MFS_1 like family DUF3129 PF11327.3 EER28671.1 - 8e-62 208.3 8.9 1.4e-61 207.4 6.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Pro_isomerase PF00160.16 EER28672.1 - 1.3e-47 161.8 0.3 1.5e-47 161.6 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.14 EER28674.1 - 2.4e-216 719.3 0.0 3.2e-216 718.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EER28674.1 - 6.8e-17 61.0 0.7 1.9e-16 59.6 0.5 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EER28674.1 - 0.0018 17.9 1.0 0.0055 16.3 0.7 2.0 1 0 0 1 1 1 1 DHHA1 domain SH3BGR PF04908.10 EER28674.1 - 0.069 13.1 0.1 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF3752 PF12572.3 EER28675.1 - 2.2e-40 138.2 9.2 2.2e-40 138.2 6.4 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) APH PF01636.18 EER28676.1 - 2.2e-14 53.7 0.6 5.2e-13 49.2 0.0 2.9 3 1 0 3 3 3 1 Phosphotransferase enzyme family Peptidase_S10 PF00450.17 EER28677.1 - 2.4e-88 297.0 0.0 3.2e-88 296.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EER28677.1 - 0.021 14.6 0.0 0.051 13.4 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family A_deaminase PF00962.17 EER28683.1 - 2.2e-112 375.2 0.0 3.1e-112 374.7 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase F-box-like PF12937.2 EER28684.1 - 0.00059 19.5 0.3 0.0014 18.3 0.0 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EER28684.1 - 0.0025 17.4 0.0 0.0078 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF3252 PF11623.3 EER28684.1 - 0.066 12.6 0.1 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) SH3_9 PF14604.1 EER28685.1 - 4.7e-31 106.1 3.8 6.8e-16 57.5 0.2 2.8 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EER28685.1 - 1.3e-25 88.5 3.4 1e-12 47.2 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EER28685.1 - 6.5e-15 54.3 0.2 6.6e-08 31.9 0.1 2.7 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EER28685.1 - 1.1e-09 38.1 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Dynamin_M PF01031.15 EER28686.1 - 5.3e-114 379.9 0.0 1e-113 379.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EER28686.1 - 4.4e-56 189.2 0.5 1.5e-55 187.5 0.0 2.1 3 0 0 3 3 3 1 Dynamin family GED PF02212.13 EER28686.1 - 5.7e-32 109.4 1.4 1.5e-31 108.1 1.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EER28686.1 - 0.0003 20.7 0.2 0.002 18.0 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER28686.1 - 0.008 16.6 0.0 0.024 15.1 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein zf-CCHC_4 PF14392.1 EER28686.1 - 0.11 12.1 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle PBP PF01161.15 EER28687.1 - 3.4e-29 101.5 0.4 5e-29 101.0 0.3 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein UAA PF08449.6 EER28688.1 - 6.4e-75 251.8 14.4 4.2e-73 245.9 10.0 2.0 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 EER28688.1 - 5.2e-05 22.9 9.3 5.2e-05 22.9 6.4 2.8 2 2 0 2 2 2 1 Triose-phosphate Transporter family Rad17 PF03215.10 EER28689.1 - 7.9e-53 179.9 0.0 1.3e-52 179.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_18 PF13238.1 EER28689.1 - 0.00094 19.4 0.2 0.007 16.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EER28689.1 - 0.0013 19.5 0.0 0.0043 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EER28689.1 - 0.0058 16.8 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EER28689.1 - 0.018 14.8 0.1 0.19 11.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_6 PF12774.2 EER28689.1 - 0.038 13.5 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_28 PF13521.1 EER28689.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain ELMO_CED12 PF04727.8 EER28690.1 - 1.1e-51 174.7 0.1 3.8e-51 173.0 0.2 1.8 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 EER28690.1 - 2.1e-08 34.0 0.8 1.6e-07 31.1 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Macoilin PF09726.4 EER28690.1 - 0.23 9.6 6.5 0.32 9.2 4.5 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF1752 PF08550.5 EER28691.1 - 2.9e-05 23.5 2.3 6.3e-05 22.4 1.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.11 EER28692.1 - 1.2e-31 109.7 28.3 5.3e-31 107.6 20.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily SUI1 PF01253.17 EER28693.1 - 7.5e-23 80.1 0.7 1.4e-22 79.2 0.5 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EER28693.1 - 0.0069 16.2 0.2 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 Transposon-encoded protein TnpV DUF755 PF05501.6 EER28693.1 - 0.75 9.8 4.4 1.3 9.0 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Rabaptin PF03528.10 EER28694.1 - 0.0096 15.8 1.8 0.032 14.1 1.2 1.9 1 1 0 1 1 1 1 Rabaptin DUF607 PF04678.8 EER28694.1 - 0.016 15.1 1.3 0.032 14.1 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF607 HD_4 PF13328.1 EER28694.1 - 0.49 10.1 5.9 0.33 10.6 1.0 2.3 1 1 1 2 2 2 0 HD domain Cgr1 PF03879.9 EER28695.1 - 1.2e-39 134.7 33.0 1.5e-39 134.5 22.9 1.0 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 EER28695.1 - 0.0092 15.3 22.4 0.011 15.1 15.5 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PRP1_N PF06424.7 EER28695.1 - 0.23 11.7 13.6 0.3 11.4 9.4 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Birna_RdRp PF04197.7 EER28695.1 - 0.63 8.0 5.7 0.65 7.9 3.9 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DDHD PF02862.12 EER28695.1 - 1.5 8.5 6.3 1.6 8.5 4.4 1.1 1 0 0 1 1 1 0 DDHD domain OmpH PF03938.9 EER28695.1 - 1.9 8.3 10.0 2.1 8.2 6.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) GAGA_bind PF06217.7 EER28695.1 - 3.5 7.5 12.0 4.2 7.2 8.3 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 EER28695.1 - 5.9 6.6 11.1 6.5 6.5 7.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Adeno_VII PF03228.9 EER28695.1 - 6.2 7.4 14.2 8.8 6.9 9.8 1.2 1 0 0 1 1 1 0 Adenoviral core protein VII Mito_carr PF00153.22 EER28696.1 - 2.4e-64 213.0 0.5 9.6e-23 79.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BP28CT PF08146.7 EER28697.1 - 0.032 13.9 0.1 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 BP28CT (NUC211) domain dCMP_cyt_deam_1 PF00383.17 EER28698.1 - 6e-11 41.9 0.0 1e-10 41.1 0.0 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EER28698.1 - 6.1e-09 35.9 0.5 8e-07 29.1 0.1 2.2 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EER28698.1 - 0.00067 19.1 0.1 0.95 8.8 0.0 2.1 2 0 0 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases BNR PF02012.15 EER28699.1 - 1.3e-07 30.3 39.5 1.9 8.6 0.0 11.4 10 0 0 10 10 10 6 BNR/Asp-box repeat PSII_BNR PF14870.1 EER28699.1 - 1.9e-05 23.8 4.4 0.044 12.7 0.0 4.7 5 1 1 6 6 6 3 Photosynthesis system II assembly factor YCF48 DUF2167 PF09935.4 EER28699.1 - 0.0058 15.4 0.2 0.061 12.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2167) Polysacc_deac_1 PF01522.16 EER28700.1 - 8.7e-22 77.0 0.0 1.4e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GFRP PF06399.8 EER28700.1 - 0.079 12.5 0.3 8 6.1 0.0 2.8 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) Methyltransf_24 PF13578.1 EER28700.1 - 0.11 13.3 0.0 0.25 12.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain RCR PF12273.3 EER28702.1 - 0.11 13.0 1.8 0.23 12.0 1.3 1.5 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red adh_short PF00106.20 EER28703.1 - 2.1e-06 27.7 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EER28703.1 - 0.00035 20.6 0.0 0.00063 19.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EER28703.1 - 0.068 12.5 0.0 0.076 12.4 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family TFIIS_M PF07500.9 EER28704.1 - 3.1e-29 101.3 1.7 8.8e-29 99.9 0.9 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EER28704.1 - 9.1e-19 66.8 4.5 1.9e-18 65.7 3.2 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EER28704.1 - 1.8e-15 56.1 0.2 4.6e-15 54.8 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 EER28704.1 - 0.026 13.8 1.3 0.065 12.6 0.9 1.7 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Chordopox_A33R PF05966.7 EER28704.1 - 0.05 12.3 0.8 0.078 11.7 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A33R protein Fungal_trans PF04082.13 EER28705.1 - 1e-23 83.5 0.1 1.7e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28705.1 - 1.1e-07 31.6 13.2 2e-07 30.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 EER28706.1 - 1.5e-40 139.2 0.0 2.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EER28706.1 - 5.2e-20 71.9 0.0 1e-19 70.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_dh_N PF08501.6 EER28706.1 - 9e-16 57.7 0.0 2.7e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EER28706.1 - 1.7e-11 44.3 0.0 3.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Prenyltransf PF01255.14 EER28708.1 - 0.00079 18.6 0.0 0.042 12.9 0.0 2.8 2 1 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Caps_synth PF05704.7 EER28708.1 - 0.1 11.7 0.2 0.29 10.2 0.2 1.6 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Sec10 PF07393.6 EER28709.1 - 7.4e-227 754.9 0.0 8.6e-227 754.7 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Ank_2 PF12796.2 EER28710.1 - 7.9e-100 327.4 17.5 1.2e-18 67.1 0.0 9.9 4 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 EER28710.1 - 1.1e-89 290.0 37.4 5.5e-08 32.2 0.0 19.1 19 0 0 19 19 19 17 Ankyrin repeat Ank_4 PF13637.1 EER28710.1 - 9.6e-73 239.3 23.6 7.6e-09 35.8 0.0 14.0 7 6 7 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER28710.1 - 4.5e-71 227.6 24.1 2.7e-06 27.0 0.0 19.4 20 0 0 20 20 20 13 Ankyrin repeat Ank_5 PF13857.1 EER28710.1 - 4.7e-58 191.9 29.5 4.3e-09 36.3 0.1 15.3 4 3 12 17 17 17 13 Ankyrin repeats (many copies) F-box-like PF12937.2 EER28710.1 - 1e-05 25.1 2.3 1.4e-05 24.7 0.8 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EER28710.1 - 0.025 14.2 0.5 0.059 13.0 0.3 1.6 1 0 0 1 1 1 0 F-box domain gag-asp_proteas PF13975.1 EER28710.1 - 0.075 12.8 1.3 3.5 7.5 0.1 2.9 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease MBOAT_2 PF13813.1 EER28711.1 - 2e-15 56.6 3.5 3.3e-15 55.9 0.5 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family VanZ PF04892.7 EER28711.1 - 0.0067 16.3 7.1 0.025 14.5 0.1 3.2 3 0 0 3 3 3 1 VanZ like family LRR_6 PF13516.1 EER28712.1 - 1.9e-07 30.4 4.2 3 8.1 0.0 7.2 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.2 EER28712.1 - 2.2e-06 27.1 5.3 0.3 10.7 0.1 5.1 5 3 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EER28712.1 - 0.00029 20.4 4.1 1e+02 3.5 0.1 6.9 8 0 0 8 8 8 0 Leucine Rich Repeat STAS_2 PF13466.1 EER28712.1 - 0.16 12.0 1.2 18 5.4 0.0 3.0 3 0 0 3 3 3 0 STAS domain PTRF_SDPR PF15237.1 EER28712.1 - 0.88 8.9 11.6 1.2 8.4 8.0 1.1 1 0 0 1 1 1 0 PTRF/SDPR family LRR_7 PF13504.1 EER28712.1 - 1.3 9.5 7.2 1.3e+02 3.4 0.0 5.9 7 0 0 7 7 6 0 Leucine rich repeat DUF1014 PF06244.7 EER28712.1 - 2.1 8.5 11.8 4.4 7.5 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) PA26 PF04636.8 EER28712.1 - 2.1 6.9 5.0 3 6.4 3.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1510 PF07423.6 EER28712.1 - 2.4 7.5 17.8 3.4 6.9 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RNB PF00773.14 EER28712.1 - 2.7 7.1 4.8 4.3 6.5 3.3 1.2 1 0 0 1 1 1 0 RNB domain Moricin PF06451.6 EER28712.1 - 3.4 7.2 5.2 11 5.5 0.1 2.7 3 0 0 3 3 3 0 Moricin GrpE PF01025.14 EER28712.1 - 5.2 6.5 20.6 7.1 6.1 13.7 1.6 1 1 1 2 2 2 0 GrpE AAA_23 PF13476.1 EER28712.1 - 6.5 7.0 12.4 9.6 6.4 8.6 1.3 1 0 0 1 1 1 0 AAA domain COX17 PF05051.8 EER28713.1 - 2.4e-21 75.4 5.0 3.2e-21 75.0 3.5 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EER28713.1 - 0.0045 16.7 1.9 0.058 13.1 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EER28713.1 - 0.049 13.5 0.9 0.087 12.7 0.6 1.5 1 1 0 1 1 1 0 CHCH domain Alg6_Alg8 PF03155.10 EER28714.1 - 9.9e-129 430.1 22.0 4.7e-84 282.8 6.3 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family RRM_1 PF00076.17 EER28715.1 - 4.7e-41 138.2 0.0 1.6e-20 72.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER28715.1 - 7.1e-36 122.0 0.0 1.4e-18 66.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER28715.1 - 6.3e-18 64.3 0.0 4.3e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_pp38 PF04846.8 EER28716.1 - 0.15 11.4 0.2 0.28 10.5 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Ribosomal_L37 PF08561.5 EER28717.1 - 2.9e-25 87.6 5.5 2.2e-24 84.8 3.8 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 TMEM154 PF15102.1 EER28718.1 - 0.0017 18.0 0.0 0.004 16.8 0.0 1.5 2 0 0 2 2 2 1 TMEM154 protein family Glycophorin_A PF01102.13 EER28718.1 - 0.0042 16.8 0.1 0.0085 15.8 0.1 1.5 1 0 0 1 1 1 1 Glycophorin A Sarcoglycan_2 PF05510.8 EER28718.1 - 0.025 12.8 0.0 0.031 12.5 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Herpes_gE PF02480.11 EER28718.1 - 0.071 11.3 0.0 0.071 11.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAG1 PF05454.6 EER28718.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4448 PF14610.1 EER28718.1 - 0.12 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF2207 PF09972.4 EER28718.1 - 0.15 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Cpn60_TCP1 PF00118.19 EER28719.1 - 1.3e-129 432.9 9.1 1.9e-129 432.4 6.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 EER28719.1 - 0.012 14.9 1.3 0.13 11.5 0.1 2.9 3 0 0 3 3 3 0 DeoC/LacD family aldolase AAA PF00004.24 EER28720.1 - 1e-40 139.0 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER28720.1 - 4.9e-06 26.7 0.0 0.00059 19.9 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EER28720.1 - 4.2e-05 23.2 0.1 0.00024 20.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EER28720.1 - 0.00023 21.2 0.1 0.0009 19.2 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_2 PF07724.9 EER28720.1 - 0.00027 20.8 0.0 0.00071 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EER28720.1 - 0.0018 17.2 0.0 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EER28720.1 - 0.0032 18.2 0.1 0.013 16.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EER28720.1 - 0.0091 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EER28720.1 - 0.0095 15.6 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EER28720.1 - 0.017 15.0 0.1 0.045 13.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EER28720.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EER28720.1 - 0.035 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EER28720.1 - 0.049 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.1 EER28720.1 - 0.051 13.1 0.1 0.65 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EER28720.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EER28720.1 - 0.08 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EER28720.1 - 0.081 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EER28720.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EER28720.1 - 0.12 12.0 0.0 11 5.6 0.0 2.5 1 1 1 2 2 2 0 Archaeal ATPase FAD_binding_2 PF00890.19 EER28721.1 - 1.7e-125 419.1 2.8 2.1e-125 418.8 1.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EER28721.1 - 1e-47 161.1 1.0 1.5e-47 160.6 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EER28721.1 - 2.6e-07 30.7 0.0 0.0014 18.5 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER28721.1 - 8.4e-06 25.0 0.3 0.014 14.4 0.0 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 EER28721.1 - 2.7e-05 23.1 1.8 0.017 14.0 1.7 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EER28721.1 - 0.00026 20.0 0.2 0.002 17.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EER28721.1 - 0.0031 16.6 0.2 0.0081 15.2 0.1 1.7 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EER28721.1 - 0.17 10.3 1.8 0.77 8.1 0.6 2.5 3 0 0 3 3 3 0 HI0933-like protein DPPIV_N PF00930.16 EER28722.1 - 2.9e-109 364.9 0.1 4e-109 364.4 0.1 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EER28722.1 - 1.5e-56 190.9 2.8 2.6e-56 190.2 1.9 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EER28722.1 - 4.7e-09 36.1 0.1 9.6e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EER28722.1 - 1.9e-06 27.5 2.3 7.6e-05 22.2 0.9 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EER28722.1 - 1.7e-05 24.8 0.1 0.00021 21.2 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EER28722.1 - 0.067 12.4 0.1 0.28 10.4 0.1 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.8 EER28722.1 - 0.13 10.5 0.0 7.6 4.7 0.0 2.2 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PI-PLC-X PF00388.14 EER28723.1 - 9.3e-62 206.7 0.1 1.6e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EER28723.1 - 1.7e-37 127.9 0.1 3.7e-37 126.9 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain HECT_2 PF09814.4 EER28724.1 - 4.5e-22 78.2 0.0 4.9e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding HECT_2 PF09814.4 EER28725.1 - 1.3e-33 116.2 0.0 1.6e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Ribosomal_S27e PF01667.12 EER28725.1 - 0.00013 21.4 0.0 0.00025 20.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 Rubredoxin PF00301.15 EER28725.1 - 0.047 13.5 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Rubredoxin DUF4243 PF14027.1 EER28726.1 - 4.8e-83 279.3 2.9 6.1e-83 278.9 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) YTV PF07639.6 EER28726.1 - 0.036 13.7 0.4 0.058 13.1 0.3 1.3 1 0 0 1 1 1 0 YTV Imm31 PF15595.1 EER28726.1 - 0.049 13.3 0.1 0.22 11.3 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 31 AAA PF00004.24 EER28727.1 - 9.9e-47 158.4 0.0 2.5e-43 147.4 0.0 3.1 2 1 1 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EER28727.1 - 2e-07 31.8 0.0 0.0013 19.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EER28727.1 - 7.7e-05 22.1 0.2 0.00077 18.9 0.0 2.5 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EER28727.1 - 0.00017 20.6 0.0 0.00041 19.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EER28727.1 - 0.00036 20.6 0.0 0.0062 16.6 0.0 3.0 2 1 0 2 2 1 1 AAA domain Parvo_NS1 PF01057.12 EER28727.1 - 0.00045 19.1 0.0 0.00076 18.4 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 EER28727.1 - 0.0011 19.0 4.7 0.018 15.0 0.1 4.2 3 2 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EER28727.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EER28727.1 - 0.0016 18.5 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.9 EER28727.1 - 0.0025 17.7 0.0 0.0059 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EER28727.1 - 0.0043 16.7 0.0 0.026 14.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EER28727.1 - 0.0048 15.6 0.0 0.0087 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EER28727.1 - 0.011 15.6 0.0 0.26 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EER28727.1 - 0.011 16.0 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EER28727.1 - 0.014 14.5 0.1 0.065 12.3 0.0 2.0 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 EER28727.1 - 0.02 14.0 0.1 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EER28727.1 - 0.021 14.5 0.0 0.064 12.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 EER28727.1 - 0.03 13.5 0.0 0.081 12.1 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EER28727.1 - 0.04 13.8 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EER28727.1 - 0.046 13.6 0.0 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EER28727.1 - 0.054 13.1 0.1 1.2 8.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EER28727.1 - 0.1 12.1 0.1 0.22 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EER28727.1 - 0.15 11.1 0.3 0.55 9.2 0.0 2.1 3 0 0 3 3 2 0 Zeta toxin PPV_E1_C PF00519.12 EER28727.1 - 0.24 9.9 0.0 0.37 9.3 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase FAD_binding_4 PF01565.18 EER28728.1 - 2.4e-19 69.2 0.3 4.4e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain zf-C2H2 PF00096.21 EER28729.1 - 0.014 15.7 5.9 0.014 15.7 4.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER28729.1 - 0.73 10.3 19.3 0.027 14.7 2.8 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger FAD_binding_3 PF01494.14 EER28730.1 - 1.2e-28 100.2 0.0 1.6e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EER28730.1 - 3.7e-11 42.5 1.1 2.2e-06 26.8 0.5 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EER28730.1 - 9.7e-09 34.3 0.0 0.0015 17.2 0.0 2.5 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EER28730.1 - 1.3e-06 28.3 0.2 4e-06 26.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EER28730.1 - 2e-05 23.6 1.0 5e-05 22.3 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EER28730.1 - 5.3e-05 23.5 0.1 0.00054 20.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER28730.1 - 0.0003 20.7 2.1 0.00078 19.3 1.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EER28730.1 - 0.0015 17.7 0.1 0.068 12.2 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EER28730.1 - 0.0017 16.9 0.9 0.0073 14.8 0.8 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EER28730.1 - 0.0033 16.5 0.6 0.0057 15.7 0.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EER28730.1 - 0.0092 14.9 1.6 0.6 8.9 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EER28730.1 - 0.025 14.6 0.0 0.12 12.3 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EER28730.1 - 0.03 13.2 2.3 0.047 12.5 1.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EER28730.1 - 0.049 13.2 0.2 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EER28730.1 - 0.12 11.4 0.2 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EER28730.1 - 0.16 11.6 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3818 PF12825.2 EER28731.1 - 4.6e-136 452.9 5.5 6.6e-136 452.4 3.8 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EER28731.1 - 3.4e-44 149.7 0.6 7e-44 148.7 0.4 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EER28731.1 - 1e-11 44.6 0.0 3.1e-10 39.8 0.0 3.2 3 1 0 3 3 3 1 PX domain zf-GRF PF06839.7 EER28732.1 - 0.018 14.9 0.6 0.042 13.7 0.4 1.6 1 0 0 1 1 1 0 GRF zinc finger Met_10 PF02475.11 EER28733.1 - 3.3e-64 216.1 0.0 4.8e-64 215.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RNA_pol_Rpb4 PF03874.11 EER28734.1 - 1.7e-23 82.8 4.8 2.4e-23 82.3 3.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 AMP-binding PF00501.23 EER28735.1 - 2.3e-72 243.6 0.0 3.6e-72 243.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER28735.1 - 3.1e-10 40.8 0.0 6.9e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CBS PF00571.23 EER28735.1 - 0.039 13.7 0.1 18 5.2 0.0 3.6 3 0 0 3 3 3 0 CBS domain RhoGAP PF00620.22 EER28736.1 - 1.8e-34 118.5 0.0 3.8e-34 117.4 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EER28736.1 - 6.4e-29 99.8 36.6 4.8e-11 42.5 6.2 5.0 5 0 0 5 5 5 4 LIM domain Nbl1_Borealin_N PF10444.4 EER28737.1 - 2.1e-21 75.0 4.7 2.1e-21 75.0 3.3 1.6 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EER28738.1 - 2.3e-09 37.5 0.0 3.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EER28738.1 - 0.0015 17.9 0.3 0.0037 16.6 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif VWA PF00092.23 EER28738.1 - 0.0034 17.1 0.4 0.006 16.3 0.3 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EER28738.1 - 0.0042 16.7 0.1 0.0081 15.7 0.0 1.4 1 1 0 1 1 1 1 Ssl1-like RSS_P20 PF11757.3 EER28738.1 - 0.0061 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Suppressor of RNA silencing P21-like Sybindin PF04099.7 EER28739.1 - 1.7e-48 163.9 0.0 2.6e-48 163.3 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EER28739.1 - 2.3e-09 37.2 0.0 6.7e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region UQ_con PF00179.21 EER28740.1 - 2e-41 140.7 0.0 7.8e-30 103.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER28740.1 - 6.3e-08 32.4 0.0 4.2e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Prokaryotic E2 family B RWD PF05773.17 EER28740.1 - 0.0016 18.2 0.0 0.03 14.2 0.0 2.4 2 1 0 2 2 2 1 RWD domain UEV PF05743.8 EER28740.1 - 0.0085 15.7 0.0 0.19 11.4 0.0 2.5 2 1 0 2 2 2 1 UEV domain p450 PF00067.17 EER28741.1 - 1.4e-24 86.4 0.0 1.8e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 EER28742.1 - 2e-48 164.5 0.1 2.8e-47 160.7 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EER28742.1 - 1.4e-18 67.2 0.6 1.2e-17 64.1 0.1 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EER28742.1 - 6.3e-13 48.2 0.1 2.5e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EER28742.1 - 1.6e-06 27.2 0.0 7.7e-06 24.9 0.0 2.0 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EER28742.1 - 0.0024 17.8 0.0 0.041 13.8 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EER28742.1 - 0.01 15.7 0.0 0.61 9.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EER28742.1 - 0.067 12.8 0.0 0.56 9.8 0.0 2.2 1 1 0 1 1 1 0 KR domain Pkinase PF00069.20 EER28743.1 - 2.7e-12 46.4 0.1 3.7e-08 32.8 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER28743.1 - 0.002 17.2 0.0 0.0039 16.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH_6_hur PF04655.9 EER28743.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Pkinase PF00069.20 EER28746.1 - 2.1e-59 200.7 0.0 4.2e-38 130.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EER28746.1 - 1.7e-29 102.6 0.0 3.4e-22 78.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EER28746.1 - 3.3e-10 39.9 0.0 7.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EER28746.1 - 4.2e-08 32.5 0.0 3.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EER28746.1 - 4.2e-06 26.6 0.0 0.0051 16.5 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family PAS PF00989.19 EER28746.1 - 0.00043 20.0 0.1 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EER28746.1 - 0.022 15.1 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain Kdo PF06293.9 EER28746.1 - 0.027 13.5 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EER28746.1 - 0.078 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EER28746.1 - 0.22 10.2 0.0 0.45 9.2 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 eIF-3_zeta PF05091.7 EER28747.1 - 1.7e-197 657.1 0.0 1.9e-197 656.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) bZIP_1 PF00170.16 EER28748.1 - 0.0052 16.7 10.1 0.011 15.6 6.9 1.6 1 1 0 1 1 1 1 bZIP transcription factor Pkinase PF00069.20 EER28749.1 - 1.4e-32 112.8 0.0 2.6e-32 111.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER28749.1 - 1.4e-08 34.1 0.0 3.4e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EER28749.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Amidase PF01425.16 EER28750.1 - 1e-95 321.1 0.0 1.2e-95 320.9 0.0 1.0 1 0 0 1 1 1 1 Amidase Acetyltransf_3 PF13302.1 EER28752.1 - 8.9e-14 51.8 0.0 1.2e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EER28752.1 - 4.1e-07 30.0 0.0 5.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER28752.1 - 4.1e-05 23.5 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family 3-dmu-9_3-mt PF06983.8 EER28754.1 - 7.3e-37 126.2 0.0 1.1e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase DUF4187 PF13821.1 EER28755.1 - 1e-24 85.8 0.1 2.6e-24 84.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EER28755.1 - 1.3e-23 83.1 1.0 1.3e-23 83.1 0.7 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EER28755.1 - 9.3e-10 39.0 0.6 2.5e-09 37.6 0.4 1.7 1 0 0 1 1 1 1 Arsenite-resistance protein 2 CBFB_NFYA PF02045.10 EER28756.1 - 2.4e-30 104.8 4.1 2.4e-30 104.8 2.9 2.9 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 EER28756.1 - 0.097 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Hus1-like protein Kinesin PF00225.18 EER28757.1 - 9.3e-113 376.3 0.5 5.1e-112 373.8 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EER28757.1 - 6.2e-41 139.3 0.0 1.2e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EER28757.1 - 5.8e-07 29.4 0.7 1.5e-06 28.1 0.5 1.8 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EER28757.1 - 1.5e-06 28.2 0.2 2.4e-05 24.3 0.0 3.0 3 0 0 3 3 3 1 FHA domain PH PF00169.24 EER28757.1 - 1.2e-05 25.3 0.0 4.7e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 PH domain Phosphodiest PF01663.17 EER28758.1 - 3.1e-86 289.9 0.6 4e-86 289.6 0.4 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EER28758.1 - 0.00018 20.8 0.1 0.013 14.7 0.1 2.3 1 1 0 1 1 1 1 Sulfatase YjgP_YjgQ PF03739.9 EER28758.1 - 0.021 13.5 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family PglZ PF08665.7 EER28758.1 - 0.029 14.0 0.1 2.1 8.0 0.0 2.7 3 0 0 3 3 3 0 PglZ domain Ofd1_CTDD PF10637.4 EER28760.1 - 1.8e-95 319.1 0.0 2.2e-90 302.4 0.1 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EER28760.1 - 6e-15 55.5 0.0 1.5e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EER28760.1 - 0.0075 15.8 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HLH PF00010.21 EER28761.1 - 7.8e-15 54.3 2.3 9.7e-15 54.0 0.7 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF3166 PF11365.3 EER28761.1 - 0.02 15.3 0.3 0.12 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) DivIC PF04977.10 EER28761.1 - 0.021 14.3 1.2 0.037 13.5 0.8 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF4404 PF14357.1 EER28761.1 - 0.025 14.9 1.8 0.058 13.8 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) RmuC PF02646.11 EER28761.1 - 0.06 12.1 0.8 0.088 11.6 0.5 1.2 1 0 0 1 1 1 0 RmuC family F-box PF00646.28 EER28763.1 - 0.16 11.6 0.2 0.46 10.2 0.0 1.8 2 0 0 2 2 2 0 F-box domain TAFII55_N PF04658.8 EER28764.1 - 2.5e-53 179.8 0.0 4.4e-53 179.1 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region MFS_1 PF07690.11 EER28765.1 - 7.4e-19 67.6 51.8 2.1e-16 59.5 8.7 3.4 3 1 1 4 4 4 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER28765.1 - 2.7e-07 29.5 11.2 2.7e-07 29.5 7.7 3.9 3 1 0 4 4 4 1 Sugar (and other) transporter DUF2975 PF11188.3 EER28766.1 - 0.31 10.7 2.6 9 6.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Pyr_redox_3 PF13738.1 EER28767.1 - 3.2e-25 89.3 0.0 2.1e-24 86.7 0.0 2.3 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER28767.1 - 2.6e-10 39.1 0.0 0.00019 19.8 0.0 2.7 3 0 0 3 3 3 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EER28767.1 - 1.5e-08 34.6 0.2 0.00024 20.9 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EER28767.1 - 5e-08 32.2 0.0 9.3e-07 28.0 0.0 2.6 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EER28767.1 - 8e-08 31.5 0.0 0.0087 15.0 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EER28767.1 - 2.9e-06 27.3 0.0 3e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EER28767.1 - 0.00012 20.7 0.0 0.019 13.4 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EER28767.1 - 0.00053 19.9 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EER28767.1 - 0.0006 18.9 0.0 0.00098 18.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EER28767.1 - 0.00068 18.6 0.0 0.25 10.1 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 EER28767.1 - 0.1 11.4 0.0 23 3.7 0.0 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EER28767.1 - 0.14 12.5 0.1 20 5.6 0.0 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase E1-E2_ATPase PF00122.15 EER28767.1 - 0.24 10.3 0.0 0.38 9.7 0.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase ketoacyl-synt PF00109.21 EER28768.1 - 9.1e-69 231.7 0.0 2e-68 230.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EER28768.1 - 6.1e-66 222.5 0.0 8.9e-66 222.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EER28768.1 - 9.7e-58 195.9 0.0 1.7e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EER28768.1 - 1.1e-53 181.6 0.0 2.3e-53 180.5 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EER28768.1 - 2.5e-42 144.6 0.0 9.1e-42 142.8 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EER28768.1 - 6.8e-30 103.3 0.1 1.7e-29 102.0 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EER28768.1 - 1.9e-05 23.8 0.4 3.7e-05 22.8 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EER28768.1 - 0.00042 20.5 0.1 0.0015 18.7 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 EER28768.1 - 0.002 17.8 0.0 0.0062 16.2 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.5 EER28768.1 - 0.027 14.1 2.8 0.059 13.0 0.3 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_5 PF12695.2 EER28768.1 - 0.029 14.1 0.6 3.1 7.5 0.0 3.3 4 0 0 4 4 4 0 Alpha/beta hydrolase family Bul1_N PF04425.7 EER28768.1 - 0.7 8.3 0.3 1.2 7.5 0.2 1.2 1 0 0 1 1 1 0 Bul1 N terminus DUF2834 PF11196.3 EER28769.1 - 0.0018 18.4 0.6 0.0018 18.4 0.4 4.6 5 1 0 5 5 5 1 Protein of unknown function (DUF2834) Ferric_reduct PF01794.14 EER28769.1 - 0.014 15.4 1.7 0.014 15.4 1.2 2.5 3 0 0 3 3 3 0 Ferric reductase like transmembrane component Glyco_hydro_43 PF04616.9 EER28770.1 - 3.5e-34 118.2 0.1 4.8e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 EER28770.1 - 0.00082 18.1 0.0 0.0026 16.5 0.0 1.7 1 1 1 2 2 2 1 Levansucrase/Invertase vWA-TerF-like PF10138.4 EER28771.1 - 1.1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EER28771.1 - 0.02 14.9 0.0 0.055 13.5 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Homeobox_KN PF05920.6 EER28772.1 - 6.4e-20 70.5 0.5 6.4e-20 70.5 0.3 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EER28772.1 - 5.3e-07 29.1 0.1 1e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain SRP72 PF08492.7 EER28774.1 - 7e-16 58.3 14.4 7e-16 58.3 10.0 2.3 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EER28774.1 - 9.9e-10 38.6 12.0 0.002 18.4 0.6 6.6 5 3 1 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EER28774.1 - 6.9e-08 31.8 13.0 0.014 15.2 0.1 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EER28774.1 - 2.2e-07 30.8 9.6 0.67 10.7 0.0 7.5 6 1 2 8 8 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EER28774.1 - 4.9e-05 23.8 14.4 0.18 12.5 0.6 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EER28774.1 - 0.0002 21.3 7.3 0.56 10.3 0.5 4.5 4 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EER28774.1 - 0.00041 19.8 7.4 0.12 12.0 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EER28774.1 - 0.00046 20.0 11.9 0.0027 17.6 0.0 4.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 EER28774.1 - 0.011 15.7 3.2 8.4 6.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.7 EER28774.1 - 0.024 14.4 0.1 1.4 8.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EER28774.1 - 0.028 14.8 10.2 44 4.8 0.7 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EER28774.1 - 0.057 13.2 0.9 2.2 8.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EER28774.1 - 0.12 12.0 7.6 10 5.8 0.0 4.6 4 1 0 4 4 4 0 TPR repeat TPR_4 PF07721.9 EER28774.1 - 0.58 10.7 5.2 8.3 7.1 0.1 4.5 4 1 2 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EER28774.1 - 1.1 9.2 8.9 29 4.7 0.1 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EER28774.1 - 1.4 8.9 12.6 0.38 10.7 0.1 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat FAD_binding_1 PF00667.15 EER28775.1 - 9.7e-44 149.4 0.0 1.5e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EER28775.1 - 1.8e-09 38.1 0.0 6.6e-09 36.3 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Med20 PF08612.6 EER28777.1 - 2.4e-76 255.8 0.0 2.9e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex EF-hand_1 PF00036.27 EER28778.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EER28778.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EER28778.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EER28778.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EER28778.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EER28778.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EER28778.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EER28778.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EER28778.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EER28778.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EER28778.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EER28778.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 EER28778.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EER28778.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EER28778.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 EER28778.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EER28778.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EER28778.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 EER28778.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EER28779.1 - 7.8e-18 63.9 1.6 7.8e-18 63.9 1.1 2.3 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EER28779.1 - 7.8e-12 45.2 0.7 7.8e-12 45.2 0.5 2.3 2 1 0 2 2 2 1 Syntaxin DUF948 PF06103.6 EER28779.1 - 0.41 10.5 2.9 8.9 6.2 0.1 3.3 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) DNA_repr_REX1B PF14966.1 EER28779.1 - 0.48 10.8 3.6 0.53 10.6 0.1 2.7 3 1 0 3 3 3 0 DNA repair REX1-B MCPsignal PF00015.16 EER28779.1 - 0.72 9.3 8.0 1.1 8.7 0.4 2.6 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CTD_bind PF04818.8 EER28780.1 - 1.8e-20 72.9 0.2 3.7e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF1266 PF06889.6 EER28780.1 - 0.061 13.1 0.3 0.061 13.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) MSP1_C PF07462.6 EER28780.1 - 0.067 11.5 0.1 0.1 10.9 0.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus CTK3 PF12243.3 EER28780.1 - 0.12 12.0 0.1 0.26 10.9 0.1 1.6 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 DUF3277 PF11681.3 EER28780.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) Clathrin_lg_ch PF01086.12 EER28781.1 - 1.8e-67 227.6 3.0 2e-67 227.4 2.1 1.0 1 0 0 1 1 1 1 Clathrin light chain rve_3 PF13683.1 EER28781.1 - 0.018 14.5 0.5 0.036 13.6 0.3 1.4 1 0 0 1 1 1 0 Integrase core domain ATP-synt_B PF00430.13 EER28781.1 - 1.2 8.9 5.9 1.9 8.3 4.1 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Acyl_transf_3 PF01757.17 EER28782.1 - 1.5e-23 83.2 30.8 2.6e-23 82.4 21.4 1.4 1 1 0 1 1 1 1 Acyltransferase family Acyl_transf_3 PF01757.17 EER28783.1 - 2.2e-28 99.1 39.4 4.1e-28 98.1 27.3 1.5 1 1 0 1 1 1 1 Acyltransferase family Mannosyl_trans3 PF11051.3 EER28784.1 - 3.6e-76 256.0 0.0 1.3e-75 254.2 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EER28784.1 - 0.17 11.2 0.0 0.32 10.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 8 CDC37_N PF03234.9 EER28785.1 - 3.2e-60 203.4 1.5 3.2e-60 203.4 1.0 2.8 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EER28785.1 - 1.2e-47 161.5 0.1 3.3e-47 160.1 0.1 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EER28785.1 - 1.1e-27 95.8 1.7 1.1e-27 95.8 1.2 2.5 2 0 0 2 2 2 1 Cdc37 C terminal domain HTH_22 PF13309.1 EER28785.1 - 0.031 14.0 0.2 0.39 10.5 0.0 2.5 2 0 0 2 2 2 0 HTH domain DUF3287 PF11690.3 EER28785.1 - 3.5 7.7 5.9 18 5.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) ABC_membrane PF00664.18 EER28786.1 - 4.2e-46 157.5 9.4 5.5e-46 157.1 6.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EER28786.1 - 8.8e-36 123.2 0.0 2.8e-35 121.5 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EER28786.1 - 9.9e-06 24.9 0.0 0.00081 18.6 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER28786.1 - 0.00098 19.1 0.4 1.4 8.8 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EER28786.1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EER28786.1 - 0.0014 18.7 0.1 0.0086 16.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EER28786.1 - 0.0019 18.2 0.6 0.0067 16.4 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EER28786.1 - 0.0028 18.4 0.1 0.0075 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EER28786.1 - 0.0081 15.5 0.0 0.051 12.9 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EER28786.1 - 0.017 14.4 0.4 0.065 12.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.4 EER28786.1 - 0.018 13.6 1.1 0.091 11.3 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF258 PF03193.11 EER28786.1 - 0.022 13.9 0.0 0.047 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF87 PF01935.12 EER28786.1 - 0.026 14.3 0.2 0.44 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA PF00004.24 EER28786.1 - 0.035 14.2 0.0 0.17 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EER28786.1 - 0.037 14.3 1.2 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EER28786.1 - 0.038 13.4 1.8 0.075 12.4 0.1 2.2 2 1 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 EER28786.1 - 0.043 13.7 0.7 0.28 11.1 0.5 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EER28786.1 - 0.078 13.2 0.1 0.26 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain MORN_2 PF07661.8 EER28786.1 - 0.21 11.7 0.6 4.5 7.6 0.6 2.7 2 0 0 2 2 2 0 MORN repeat variant Nucleoside_tran PF01733.13 EER28787.1 - 1.2e-41 142.8 20.1 2e-29 102.7 2.5 2.6 2 1 1 3 3 3 2 Nucleoside transporter MFS_1 PF07690.11 EER28787.1 - 3.8e-13 48.8 26.4 2.1e-05 23.4 3.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Lactamase_B PF00753.22 EER28788.1 - 0.0036 16.9 0.3 0.0051 16.4 0.2 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Fungal_trans PF04082.13 EER28789.1 - 1.9e-09 36.8 0.4 1.9e-09 36.8 0.3 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EER28789.1 - 5.7e-07 29.4 14.8 0.0045 17.2 4.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER28789.1 - 1.9e-06 27.8 2.9 1.9e-06 27.8 2.0 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER28789.1 - 1.2e-05 25.3 13.9 0.0098 16.1 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EER28789.1 - 0.17 12.1 4.4 0.47 10.7 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EER28789.1 - 0.46 10.4 7.2 4.2 7.4 1.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3353 PF11833.3 EER28789.1 - 2.2 7.7 6.7 12 5.2 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3353) CMD PF02627.15 EER28790.1 - 2e-21 75.5 0.1 3e-21 75.0 0.1 1.2 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family NAD_binding_11 PF14833.1 EER28791.1 - 5.4e-24 84.5 0.0 7.7e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EER28791.1 - 9.7e-22 77.5 0.0 1.6e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.10 EER28791.1 - 0.0058 15.4 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EER28791.1 - 0.021 15.2 0.0 0.05 14.0 0.0 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EER28791.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3635 PF12330.3 EER28792.1 - 1.4e-05 25.0 0.1 4.6e-05 23.4 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3635) DUF2404 PF10296.4 EER28793.1 - 0.00044 20.3 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DUF1518 PF07469.7 EER28793.1 - 0.12 12.5 0.1 0.12 12.5 0.1 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1518) DUF1682 PF07946.9 EER28794.1 - 4.6e-110 367.4 0.6 5.4e-110 367.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) PPR_3 PF13812.1 EER28795.1 - 0.0095 16.1 0.5 0.071 13.4 0.0 2.7 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.15 EER28795.1 - 0.03 14.2 0.0 7.1 6.8 0.0 2.9 2 0 0 2 2 2 0 PPR repeat DUF77 PF01910.12 EER28796.1 - 2e-30 104.3 0.0 2.3e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 EER28796.1 - 0.075 13.1 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 YKOF-related Family Retro_M PF02813.9 EER28796.1 - 0.091 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Retroviral M domain Ins_P5_2-kin PF06090.7 EER28797.1 - 2.5e-67 227.1 0.0 3e-67 226.8 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase YEATS PF03366.11 EER28798.1 - 1.1e-35 121.2 0.7 1.7e-35 120.5 0.5 1.3 1 0 0 1 1 1 1 YEATS family NAD_binding_10 PF13460.1 EER28799.1 - 8.6e-11 42.1 0.0 1e-09 38.7 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EER28799.1 - 5.3e-06 26.0 0.0 3.3e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EER28799.1 - 0.00011 21.0 0.0 0.00054 18.7 0.0 2.0 3 0 0 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EER28799.1 - 0.0036 17.2 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EER28799.1 - 0.0064 15.4 0.1 0.51 9.2 0.1 2.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EER28799.1 - 0.11 11.3 0.0 0.76 8.6 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SYF2 PF08231.7 EER28800.1 - 1.6e-52 177.6 9.7 1.6e-52 177.6 6.7 1.7 2 0 0 2 2 2 1 SYF2 splicing factor YcaO PF02624.11 EER28800.1 - 0.69 9.3 4.3 1.5 8.2 2.9 1.7 1 1 0 1 1 1 0 YcaO-like family Velvet PF11754.3 EER28803.1 - 3.5e-45 154.1 0.0 4.3e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Sel1 PF08238.7 EER28804.1 - 8.2e-06 26.2 2.5 0.071 13.7 0.2 3.8 3 0 0 3 3 3 2 Sel1 repeat TPR_8 PF13181.1 EER28804.1 - 0.00068 19.2 2.5 0.19 11.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EER28804.1 - 0.0013 18.5 0.7 0.85 9.6 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EER28804.1 - 0.0013 18.2 1.4 2 8.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EER28804.1 - 0.14 12.1 3.9 0.62 10.0 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EER28804.1 - 0.76 10.1 5.1 0.57 10.5 0.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat PH_10 PF15411.1 EER28805.1 - 2.3e-26 92.2 0.0 4e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EER28805.1 - 1.9e-09 37.3 0.0 1e-08 35.0 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EER28805.1 - 7.2e-09 35.6 0.0 1.7e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EER28805.1 - 1.3e-06 28.1 9.0 1.3e-06 28.1 6.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EER28805.1 - 0.024 14.7 3.8 0.052 13.6 2.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 EER28805.1 - 0.031 14.0 8.4 0.061 13.0 5.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EER28805.1 - 0.041 13.8 8.2 0.1 12.6 5.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER28805.1 - 0.062 12.9 9.0 0.15 11.7 6.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EER28805.1 - 2.1 8.4 8.1 4.5 7.3 5.6 1.6 1 0 0 1 1 1 0 RING-like domain Ribosomal_L12 PF00542.14 EER28806.1 - 4.4e-19 68.2 8.1 4e-18 65.1 4.5 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain HisG_C PF08029.6 EER28806.1 - 0.039 13.8 0.2 0.14 12.1 0.1 2.0 1 1 0 1 1 1 0 HisG, C-terminal domain Cpn60_TCP1 PF00118.19 EER28807.1 - 8.4e-134 446.8 2.7 9.6e-134 446.6 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family E1_dh PF00676.15 EER28808.1 - 1.6e-113 378.4 0.1 1.9e-113 378.1 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EER28808.1 - 1e-05 24.6 0.0 1.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EER28808.1 - 0.0056 16.2 1.7 0.01 15.4 1.2 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain KRTAP7 PF15034.1 EER28808.1 - 1.3 9.6 6.0 1.1 9.9 0.2 2.8 2 1 0 2 2 2 0 KRTAP type 7 family S4 PF01479.20 EER28809.1 - 7.5e-16 57.2 0.0 1.5e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EER28809.1 - 0.0099 15.4 0.0 0.023 14.2 0.0 1.6 1 0 0 1 1 1 1 S4 domain HSP70 PF00012.15 EER28809.1 - 0.13 10.1 5.0 0.18 9.6 3.5 1.2 1 0 0 1 1 1 0 Hsp70 protein SOBP PF15279.1 EER28809.1 - 0.45 10.8 8.5 0.75 10.1 5.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GDPD PF03009.12 EER28810.1 - 7.7e-20 71.4 0.0 1.4e-19 70.6 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF3636 PF12331.3 EER28811.1 - 8.9e-57 190.8 0.3 2.1e-56 189.6 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3636) TPR_MLP1_2 PF07926.7 EER28811.1 - 0.064 13.0 12.6 0.018 14.8 3.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EER28811.1 - 0.079 11.9 10.8 0.15 11.0 7.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0242 PF06785.6 EER28811.1 - 0.29 9.7 11.0 0.42 9.2 7.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Prok-TraM PF09228.5 EER28811.1 - 0.86 9.7 6.8 1.3 9.1 1.0 2.6 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Cluap1 PF10234.4 EER28811.1 - 1 8.5 10.4 1.6 7.8 7.2 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 RAP1 PF07218.6 EER28811.1 - 1.5 6.8 4.1 2.2 6.2 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) TMF_TATA_bd PF12325.3 EER28811.1 - 1.7 8.3 15.2 0.38 10.5 3.6 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CTP_transf_1 PF01148.15 EER28812.1 - 3.8e-83 279.0 28.3 4.8e-83 278.7 19.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Cyclin_N PF00134.18 EER28813.1 - 4.1e-10 39.2 0.1 8.6e-09 35.0 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-C2H2_4 PF13894.1 EER28814.1 - 0.00044 20.3 37.8 0.063 13.6 0.7 6.4 5 1 1 6 6 6 5 C2H2-type zinc finger zf-met PF12874.2 EER28814.1 - 0.0015 18.6 24.7 0.039 14.1 0.2 5.2 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EER28814.1 - 0.0016 18.4 3.2 0.0016 18.4 2.2 6.2 6 1 1 7 7 7 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EER28814.1 - 0.0099 16.1 40.9 0.7 10.3 0.3 6.4 6 0 0 6 6 6 5 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EER28814.1 - 10 6.3 37.6 15 5.7 2.1 4.3 1 1 4 5 5 5 0 C2H2 type zinc-finger (2 copies) GST_N_3 PF13417.1 EER28815.1 - 3.2e-15 56.1 0.2 1.7e-14 53.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EER28815.1 - 7.1e-11 41.9 0.4 3.4e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER28815.1 - 9.8e-06 25.3 0.2 1.8e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EER28815.1 - 0.00079 19.5 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EER28815.1 - 0.0035 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EER28815.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fructosamin_kin PF03881.9 EER28816.1 - 1.2e-59 201.6 0.0 2.3e-49 167.9 0.0 3.0 3 0 0 3 3 3 2 Fructosamine kinase APH PF01636.18 EER28816.1 - 0.00034 20.4 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Arm PF00514.18 EER28817.1 - 1.2e-20 72.4 5.2 0.00033 20.3 0.0 10.0 11 0 0 11 11 11 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EER28817.1 - 0.00024 21.4 2.7 12 6.4 0.0 6.6 6 0 0 6 6 6 1 HEAT-like repeat V-ATPase_H_N PF03224.9 EER28817.1 - 0.0028 16.8 0.7 0.46 9.5 0.0 3.8 4 1 0 4 4 4 1 V-ATPase subunit H HEAT PF02985.17 EER28817.1 - 0.004 17.1 10.0 1.2 9.3 0.0 6.0 7 0 0 7 7 7 2 HEAT repeat Ric8 PF10165.4 EER28817.1 - 0.047 12.4 0.8 2.7 6.7 0.0 3.4 4 0 0 4 4 4 0 Guanine nucleotide exchange factor synembryn Cyclin PF08613.6 EER28818.1 - 5.4e-29 101.5 0.0 7.9e-29 100.9 0.0 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EER28818.1 - 5.9e-05 22.6 0.0 9.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain dCMP_cyt_deam_1 PF00383.17 EER28819.1 - 0.00039 20.0 1.9 0.0094 15.5 1.3 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF445 PF04286.7 EER28820.1 - 0.12 11.8 17.8 0.045 13.2 4.9 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF445) Glyoxalase_2 PF12681.2 EER28821.1 - 4.6e-08 33.6 0.0 6.4e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EER28821.1 - 0.00025 21.0 0.0 0.00048 20.1 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Chs3p PF12271.3 EER28822.1 - 5.7e-87 291.4 5.9 7.2e-87 291.0 4.1 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DLH PF01738.13 EER28823.1 - 6e-24 84.5 0.0 6.8e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EER28823.1 - 1.8e-05 24.5 0.0 2.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EER28823.1 - 0.0055 16.1 0.0 0.0059 16.0 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF2305 PF10230.4 EER28823.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) BAAT_C PF08840.6 EER28823.1 - 0.036 13.7 0.0 0.25 10.9 0.0 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cadherin PF00028.12 EER28823.1 - 0.057 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Cadherin domain UCH PF00443.24 EER28824.1 - 1.1e-49 168.9 0.0 2.6e-49 167.7 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER28824.1 - 1.6e-24 86.9 0.0 2.4e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase GST_C_4 PF14834.1 EER28824.1 - 0.027 14.3 0.1 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-C3HC4_2 PF13923.1 EER28825.1 - 4.4e-08 33.0 8.9 7.5e-08 32.2 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER28825.1 - 2.7e-07 30.3 7.5 4.8e-07 29.4 5.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EER28825.1 - 2.7e-07 30.1 7.3 5.3e-07 29.1 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER28825.1 - 3.8e-07 29.6 5.3 6.7e-07 28.8 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EER28825.1 - 2.2e-06 27.4 6.0 1.4e-05 24.8 4.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EER28825.1 - 3.3e-05 23.5 4.8 6.8e-05 22.5 3.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EER28825.1 - 0.035 13.6 4.9 0.065 12.7 3.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EER28825.1 - 0.053 13.2 5.6 0.036 13.7 2.6 1.7 1 1 0 1 1 1 0 RING-type zinc-finger PgaD PF13994.1 EER28825.1 - 0.1 12.0 0.4 0.21 11.0 0.3 1.4 1 0 0 1 1 1 0 PgaD-like protein ERG4_ERG24 PF01222.12 EER28826.1 - 1.5e-142 475.1 19.3 1.8e-142 474.8 13.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF2945 PF11160.3 EER28827.1 - 0.13 12.0 1.7 0.29 10.9 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) GFO_IDH_MocA PF01408.17 EER28828.1 - 5.3e-26 91.5 0.0 9.9e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EER28828.1 - 0.027 14.7 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Na_H_Exchanger PF00999.16 EER28829.1 - 2.3e-38 131.7 17.1 3e-38 131.3 11.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EER28829.1 - 0.99 9.3 3.7 2 8.4 0.4 2.9 2 1 0 2 2 2 0 YrhC-like protein NDUF_B12 PF08122.7 EER28829.1 - 2.2 8.0 4.2 4.6 7.0 0.8 2.9 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Cauli_VI PF01693.11 EER28830.1 - 1.5e-32 111.3 6.7 9.2e-16 57.6 0.7 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EER28830.1 - 2.3e-29 102.3 0.0 4e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 RNase H FMN_dh PF01070.13 EER28831.1 - 2e-101 339.3 0.0 2.5e-101 339.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EER28831.1 - 5.6e-21 74.1 0.0 1.3e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EER28831.1 - 2.9e-07 29.7 0.1 4.6e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EER28831.1 - 1.1e-05 24.4 0.0 0.00043 19.2 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EER28831.1 - 0.0079 15.3 1.0 0.19 10.8 0.2 2.4 1 1 1 2 2 2 1 Nitronate monooxygenase ATP11 PF06644.6 EER28831.1 - 0.018 14.5 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 ATP11 protein His_biosynth PF00977.16 EER28831.1 - 0.051 12.8 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF202 PF02656.10 EER28832.1 - 0.002 18.2 3.1 0.002 18.2 2.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF3169 PF11368.3 EER28832.1 - 0.03 13.5 0.1 0.035 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF998 PF06197.8 EER28832.1 - 0.058 12.7 3.9 0.28 10.4 2.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF998) 6PF2K PF01591.13 EER28833.1 - 2.5e-68 229.4 0.0 2.2e-47 161.0 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EER28833.1 - 1.3e-24 87.0 0.0 4.6e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EER28833.1 - 0.0003 20.6 0.0 0.38 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EER28833.1 - 0.0063 17.3 0.0 0.017 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EER28833.1 - 0.008 15.2 0.0 1.7 7.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin KTI12 PF08433.5 EER28833.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 VTC PF09359.5 EER28834.1 - 6.9e-91 304.1 0.1 1.3e-90 303.2 0.1 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EER28834.1 - 1.4e-16 61.1 24.0 1.2e-11 44.9 3.7 4.3 2 2 1 3 3 3 2 SPX domain DUF202 PF02656.10 EER28834.1 - 3.1e-10 40.1 2.8 3.1e-10 40.1 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CYTH PF01928.16 EER28834.1 - 0.0045 16.6 0.2 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 CYTH domain DUF3435 PF11917.3 EER28836.1 - 0.042 12.5 1.9 0.088 11.5 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF885 PF05960.6 EER28836.1 - 0.045 12.9 6.5 0.057 12.5 4.5 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) IncA PF04156.9 EER28836.1 - 0.23 11.0 6.5 0.37 10.3 4.5 1.3 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 EER28837.1 - 2.2e-37 128.6 29.3 6.9e-36 123.6 6.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER28837.1 - 4.1e-12 45.4 0.7 6.6e-12 44.7 0.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter DUF791 PF05631.9 EER28837.1 - 0.0026 16.5 1.2 0.0029 16.3 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 EER28837.1 - 0.003 16.0 3.5 0.003 16.0 2.4 2.1 2 1 0 2 2 2 1 MFS/sugar transport protein LacY_symp PF01306.14 EER28837.1 - 0.0031 16.1 1.4 0.0057 15.2 1.0 1.3 1 0 0 1 1 1 1 LacY proton/sugar symporter DUF1129 PF06570.6 EER28837.1 - 0.0057 15.9 0.8 2.3 7.4 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1129) Orbi_VP6 PF01516.11 EER28838.1 - 3.8 6.4 7.5 5.7 5.9 5.2 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 WD40 PF00400.27 EER28839.1 - 2.9e-24 84.0 3.4 1.9e-09 37.0 0.0 7.1 6 1 1 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 EER28839.1 - 7.1e-11 41.9 1.8 2.9e-10 39.9 1.2 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 EER28839.1 - 1.2e-08 34.1 0.4 3.3e-08 32.7 0.1 1.8 3 0 0 3 3 3 1 Coatomer WD associated region eIF2A PF08662.6 EER28839.1 - 0.0017 18.0 0.9 0.018 14.7 0.1 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EER28839.1 - 0.01 13.6 0.2 0.026 12.3 0.1 1.6 1 1 0 1 1 1 0 IKI3 family DNA_pol_alpha_N PF12254.3 EER28839.1 - 0.038 13.8 5.6 0.14 11.9 3.8 1.9 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal MMS1_N PF10433.4 EER28839.1 - 0.12 10.5 0.0 0.81 7.7 0.0 2.2 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term p450 PF00067.17 EER28840.1 - 2.7e-11 42.6 0.0 1.9e-08 33.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 RNA12 PF10443.4 EER28841.1 - 4.9e-162 539.3 0.0 6.8e-162 538.8 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EER28841.1 - 5.4e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EER28841.1 - 0.00054 20.0 0.1 0.003 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RRM_1 PF00076.17 EER28841.1 - 0.089 12.4 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3128 PF11326.3 EER28842.1 - 1.4e-30 105.2 5.4 2.8e-30 104.2 3.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Glu_synthase PF01645.12 EER28843.1 - 1.5e-158 527.5 0.0 2.2e-158 526.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EER28843.1 - 1.3e-130 435.2 0.0 2.1e-130 434.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EER28843.1 - 5.2e-118 393.4 0.0 1e-117 392.5 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EER28843.1 - 1.4e-66 223.3 4.9 2.6e-66 222.4 3.4 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EER28843.1 - 1.8e-22 79.0 0.1 4.1e-22 77.8 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EER28843.1 - 3.9e-17 62.8 0.0 1.7e-16 60.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER28843.1 - 1e-10 42.0 0.9 5.9e-05 23.2 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER28843.1 - 9.8e-09 35.1 0.1 3.9e-08 33.2 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EER28843.1 - 1.7e-06 27.4 0.3 3.3e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EER28843.1 - 4.2e-06 27.0 0.1 0.003 17.9 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EER28843.1 - 1.5e-05 24.3 0.2 2.7e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EER28843.1 - 2.8e-05 23.1 1.3 0.00013 20.9 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EER28843.1 - 4.7e-05 22.0 0.3 4.7e-05 22.0 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EER28843.1 - 0.00016 20.7 4.9 0.00017 20.6 0.5 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EER28843.1 - 0.00093 18.3 0.1 0.0018 17.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EER28843.1 - 0.0033 16.5 0.3 0.0094 15.0 0.1 1.7 2 0 0 2 2 1 1 Thi4 family AlaDh_PNT_C PF01262.16 EER28843.1 - 0.0069 15.9 0.9 0.015 14.8 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EER28843.1 - 0.0084 16.3 1.7 1.2 9.3 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.17 EER28843.1 - 0.0099 14.7 2.9 0.01 14.7 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EER28843.1 - 0.02 14.6 0.1 0.052 13.2 0.0 1.8 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMO-like PF00743.14 EER28843.1 - 0.024 12.8 0.1 1.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.16 EER28843.1 - 0.031 14.1 0.9 7.3 6.4 0.0 2.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.15 EER28843.1 - 0.13 12.3 0.3 30 4.7 0.1 2.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MADF_DNA_bdg PF10545.4 EER28843.1 - 0.14 12.3 1.2 0.37 11.0 0.8 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like FMN_dh PF01070.13 EER28843.1 - 0.15 10.8 1.2 0.55 9.0 0.6 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase 2-Hacid_dh_C PF02826.14 EER28843.1 - 0.39 9.8 1.4 0.71 8.9 0.0 2.1 3 0 0 3 3 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA_15 PF13175.1 EER28843.1 - 0.52 9.3 2.2 0.79 8.7 1.5 1.1 1 0 0 1 1 1 0 AAA ATPase domain 3HCDH_N PF02737.13 EER28843.1 - 1.8 8.2 3.7 0.41 10.2 0.1 1.8 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PP2C PF00481.16 EER28844.1 - 4.1e-21 75.5 0.0 4.6e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EER28844.1 - 0.042 13.2 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C PS_Dcarbxylase PF02666.10 EER28845.1 - 4.1e-46 156.8 0.0 5.1e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Trypan_PARP PF05887.6 EER28846.1 - 0.42 10.4 17.2 0.61 9.8 11.9 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HSP70 PF00012.15 EER28847.1 - 6.4e-271 899.5 6.6 7.3e-271 899.3 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EER28847.1 - 6.7e-18 64.3 0.1 8e-17 60.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EER28847.1 - 0.0031 17.1 0.0 0.0074 15.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EER28847.1 - 0.0037 16.3 0.1 0.053 12.6 0.0 2.3 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase StbA PF06406.6 EER28847.1 - 0.033 13.1 0.0 0.074 11.9 0.0 1.6 1 0 0 1 1 1 0 StbA protein FtsA PF14450.1 EER28847.1 - 0.059 13.2 5.3 1.6 8.5 0.4 3.6 2 2 0 2 2 2 0 Cell division protein FtsA DUF1843 PF08898.5 EER28847.1 - 2.2 8.3 5.2 1.2 9.2 0.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) CHZ PF09649.5 EER28848.1 - 1.3e-16 59.4 2.7 1.3e-16 59.4 1.9 2.3 2 0 0 2 2 2 1 Histone chaperone domain CHZ Glyoxalase_2 PF12681.2 EER28849.1 - 1.4e-10 41.7 0.0 1.7e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EER28849.1 - 0.0031 17.5 0.0 0.0046 16.9 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SNARE PF05739.14 EER28850.1 - 2.4e-10 39.9 0.9 2.9e-10 39.6 0.6 1.1 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EER28850.1 - 0.024 14.0 0.1 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 YqzM PF14141.1 EER28850.1 - 2.4 8.0 5.3 0.31 10.8 0.8 1.7 2 0 0 2 2 2 0 YqzM-like protein Apc15p PF05841.6 EER28851.1 - 9e-26 91.0 3.3 5e-25 88.6 0.2 2.4 2 0 0 2 2 2 1 Apc15p protein Kdo PF06293.9 EER28852.1 - 0.0012 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EER28852.1 - 0.043 12.9 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain DYW_deaminase PF14432.1 EER28855.1 - 0.00012 22.0 0.0 0.00013 21.9 0.0 1.3 1 1 0 1 1 1 1 DYW family of nucleic acid deaminases Sipho_Gp157 PF05565.6 EER28855.1 - 0.026 14.0 1.0 0.026 14.0 0.7 1.4 2 0 0 2 2 2 0 Siphovirus Gp157 Pyr_redox PF00070.22 EER28855.1 - 0.06 13.7 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.1 EER28856.1 - 7.3e-08 32.3 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 EER28856.1 - 0.062 13.3 0.1 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases DUF3435 PF11917.3 EER28857.1 - 1.5e-89 300.6 0.0 1.7e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) p450 PF00067.17 EER28858.1 - 1.5e-11 43.5 0.0 1.7e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PAM2 PF07145.10 EER28858.1 - 0.34 10.5 1.3 1.1 8.9 0.9 1.8 1 0 0 1 1 1 0 Ataxin-2 C-terminal region APH PF01636.18 EER28859.1 - 5.4e-12 45.9 0.4 4.2e-11 43.0 0.3 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family CBM_5_12_2 PF14600.1 EER28859.1 - 0.076 12.6 0.1 0.21 11.2 0.1 1.8 1 0 0 1 1 1 0 Cellulose-binding domain HNH_2 PF13391.1 EER28860.1 - 5.4e-17 61.3 0.0 1.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease APH PF01636.18 EER28861.1 - 4.9e-18 65.7 0.0 3.6e-17 62.8 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EER28861.1 - 0.0017 17.3 0.0 0.051 12.5 0.0 2.1 2 0 0 2 2 2 1 Fructosamine kinase DUF1679 PF07914.6 EER28861.1 - 0.017 13.7 0.0 0.2 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EER28861.1 - 0.078 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EER28861.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EER28862.1 - 1.7e-10 40.5 0.0 2.1e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF2153 PF09921.4 EER28862.1 - 0.12 12.0 0.0 0.37 10.4 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) Pkinase PF00069.20 EER28863.1 - 7.2e-24 84.3 0.0 1.6e-23 83.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER28863.1 - 2.4e-14 53.0 0.0 1.6e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EER28863.1 - 0.082 12.6 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HCO3_cotransp PF00955.16 EER28864.1 - 1.2e-54 185.8 12.7 1.8e-32 112.7 4.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family Sas10_Utp3 PF04000.10 EER28866.1 - 6e-17 61.6 0.0 1.2e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pyr_redox_3 PF13738.1 EER28868.1 - 9.9e-22 77.9 0.0 7.3e-21 75.1 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER28868.1 - 1.2e-17 63.2 0.0 8.4e-17 60.5 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EER28868.1 - 5.9e-09 36.0 0.0 2e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EER28868.1 - 1.8e-07 30.3 0.0 1.1e-05 24.4 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EER28868.1 - 3.6e-06 27.2 2.0 0.059 13.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER28868.1 - 6.1e-06 26.1 3.4 7.7e-06 25.8 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EER28868.1 - 4.9e-05 23.1 0.3 0.017 14.8 0.1 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EER28868.1 - 0.00023 21.2 0.4 0.099 12.7 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EER28868.1 - 0.00025 20.0 0.1 0.00025 20.0 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EER28868.1 - 0.0013 18.3 0.3 0.0023 17.6 0.2 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EER28868.1 - 0.0018 18.5 0.0 0.084 13.1 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EER28868.1 - 0.011 15.3 1.0 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EER28868.1 - 0.31 9.4 3.2 0.58 8.5 0.4 2.2 2 0 0 2 2 2 0 HI0933-like protein Phage_Gp23 PF10669.4 EER28871.1 - 0.0091 16.1 2.6 0.0091 16.1 1.8 2.4 2 0 0 2 2 2 1 Protein gp23 (Bacteriophage A118) Neugrin PF06413.6 EER28871.1 - 0.017 14.9 5.1 0.033 14.0 3.5 1.4 1 0 0 1 1 1 0 Neugrin BTV_NS2 PF04514.7 EER28871.1 - 0.39 9.5 9.4 0.62 8.8 6.5 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2146 PF10220.4 EER28871.1 - 0.48 8.3 7.7 0.71 7.7 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF2937 PF11157.3 EER28871.1 - 1.2 8.4 7.9 2.1 7.6 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Neur_chan_memb PF02932.11 EER28871.1 - 1.5 8.6 4.1 2.1 8.1 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S8 PF00082.17 EER28872.1 - 1e-45 156.0 16.6 1.5e-45 155.5 11.5 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER28872.1 - 2.8e-17 63.0 0.0 5.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Mito_carr PF00153.22 EER28873.1 - 1e-60 201.4 6.2 4.3e-21 74.4 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIIIC_delta PF12657.2 EER28874.1 - 4.8e-46 156.6 3.2 5.2e-46 156.5 0.2 2.5 3 0 0 3 3 3 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EER28874.1 - 1.3e-26 92.3 1.6 3.6e-26 90.9 1.1 1.8 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DUF2793 PF10983.3 EER28874.1 - 0.018 14.7 0.0 0.081 12.7 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2793) Myb_DNA-bind_3 PF12776.2 EER28875.1 - 8.6e-10 39.1 3.7 1.4e-09 38.4 2.6 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EER28875.1 - 0.0029 17.7 2.9 0.005 16.9 2.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Glyco_trans_1_4 PF13692.1 EER28876.1 - 1.1e-25 90.3 0.0 8.8e-25 87.4 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EER28876.1 - 3.6e-05 23.9 1.1 0.00013 22.1 0.4 2.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EER28876.1 - 0.0018 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EER28876.1 - 0.039 13.3 0.0 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferases group 1 Cation_efflux PF01545.16 EER28877.1 - 1.1e-52 178.9 14.0 1.1e-52 178.9 9.7 1.7 2 0 0 2 2 2 1 Cation efflux family Zip PF02535.17 EER28877.1 - 0.00015 20.9 19.5 0.14 11.1 0.1 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter Thiolase_N PF00108.18 EER28878.1 - 3.5e-96 321.2 2.9 4.6e-96 320.8 2.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EER28878.1 - 7.9e-37 125.4 0.4 7.9e-37 125.4 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EER28878.1 - 0.0036 16.8 2.1 0.017 14.6 1.1 2.1 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain 5_nucleotid_C PF02872.13 EER28879.1 - 4.9e-35 120.8 0.0 2e-34 118.8 0.0 1.9 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EER28879.1 - 8.2e-09 35.1 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_1 PF00300.17 EER28880.1 - 1.6e-09 38.0 0.0 2e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Kinesin PF00225.18 EER28881.1 - 2.8e-112 374.7 0.2 2.8e-112 374.7 0.2 1.7 2 0 0 2 2 2 1 Kinesin motor domain DUF1895 PF08988.5 EER28881.1 - 1 9.4 9.3 0.69 9.9 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1895) UQ_con PF00179.21 EER28882.1 - 3.7e-52 175.4 0.0 4.2e-52 175.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER28882.1 - 1.9e-06 27.6 0.0 2.2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EER28882.1 - 0.037 13.9 0.1 0.067 13.0 0.0 1.6 1 1 0 1 1 1 0 RWD domain Pkinase PF00069.20 EER28883.1 - 1e-10 41.2 0.0 2.4e-10 40.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain EMP70 PF02990.11 EER28884.1 - 6.9e-180 598.9 0.5 8.6e-180 598.6 0.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 EER28884.1 - 0.029 14.4 0.0 0.029 14.4 0.0 4.3 3 2 2 5 5 5 0 NfeD-like C-terminal, partner-binding EF-hand_7 PF13499.1 EER28885.1 - 2.7e-32 110.6 15.1 2e-12 47.0 0.5 2.9 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EER28885.1 - 1e-25 86.9 10.1 3.5e-08 32.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EER28885.1 - 3.2e-24 82.5 0.9 5.3e-06 25.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EER28885.1 - 1.8e-18 64.9 8.6 2.4e-05 23.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EER28885.1 - 5.8e-15 54.6 12.2 5.1e-06 26.0 1.2 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EER28885.1 - 1.1e-08 34.7 4.2 0.0018 18.0 0.1 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EER28885.1 - 0.0017 17.9 0.6 1.8 8.3 0.0 3.3 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 EER28885.1 - 0.0036 17.1 0.1 0.042 13.7 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EER28885.1 - 0.023 14.7 0.2 0.57 10.2 0.0 2.7 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.6 EER28885.1 - 0.094 12.7 0.1 5.4 7.1 0.0 2.5 2 1 0 2 2 2 0 EF hand Mad3_BUB1_II PF08171.6 EER28885.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.5 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 Rer1 PF03248.8 EER28886.1 - 0.015 14.8 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 Rer1 family UQ_con PF00179.21 EER28887.1 - 1.5e-43 147.5 0.0 1.7e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER28887.1 - 0.048 13.4 0.2 0.081 12.6 0.2 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B CFEM PF05730.6 EER28888.1 - 1.3e-12 47.3 6.3 2.1e-12 46.6 4.4 1.4 1 0 0 1 1 1 1 CFEM domain Aminotran_1_2 PF00155.16 EER28889.1 - 7.1e-16 58.1 0.0 1.2e-08 34.3 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EER28889.1 - 0.014 13.6 0.0 0.026 12.7 0.0 1.3 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EER28889.1 - 0.015 14.3 0.4 0.04 12.9 0.0 1.6 1 1 1 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Med4 PF10018.4 EER28891.1 - 4.1e-35 120.8 5.3 8.3e-35 119.8 3.7 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 MFS_1 PF07690.11 EER28892.1 - 5.8e-26 91.0 13.6 5.8e-26 91.0 9.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER28892.1 - 2e-11 43.1 0.8 2e-11 43.1 0.5 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EER28892.1 - 0.0012 17.1 1.9 0.0012 17.1 1.3 2.0 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EER28893.1 - 2.6e-27 95.4 26.6 2.6e-27 95.4 18.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER28893.1 - 0.0041 15.3 1.6 0.0076 14.4 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.2 EER28894.1 - 1.2e-08 34.5 0.5 3.1e-08 33.1 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER28894.1 - 2.2e-06 27.1 0.0 4.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Oxidored-like PF09791.4 EER28894.1 - 0.066 12.6 0.5 0.3 10.5 0.3 2.1 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal HTH_Tnp_Tc5 PF03221.11 EER28895.1 - 9.3e-16 57.4 0.0 2.6e-15 55.9 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_Tnp_ISL3 PF13542.1 EER28895.1 - 0.0036 16.4 0.1 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 V-SNARE PF05008.10 EER28895.1 - 0.1 12.7 0.9 0.28 11.3 0.2 1.9 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus RabGAP-TBC PF00566.13 EER28896.1 - 9.5e-49 165.7 1.7 2.2e-48 164.5 0.0 2.4 2 1 1 3 3 3 1 Rab-GTPase-TBC domain Histone_HNS PF00816.16 EER28896.1 - 2.1 8.9 0.0 2.1 8.9 0.0 3.4 3 0 0 3 3 3 0 H-NS histone family DNA_topoisoIV PF00521.15 EER28897.1 - 1.5e-133 445.7 0.2 3.5e-133 444.5 0.0 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EER28897.1 - 1.4e-36 125.2 2.5 3.6e-36 123.9 1.8 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EER28897.1 - 1.1e-14 54.1 0.6 7.1e-13 48.3 0.0 3.5 3 0 0 3 3 3 1 Toprim domain HATPase_c PF02518.21 EER28897.1 - 3.2e-11 42.9 0.0 1.6e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 EER28900.1 - 6.6e-36 123.4 2.0 8.5e-36 123.1 1.4 1.1 1 0 0 1 1 1 1 Reticulon Cytochrome-c551 PF10643.4 EER28900.1 - 0.033 13.4 0.8 0.051 12.8 0.5 1.4 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Acyl-CoA_dh_1 PF00441.19 EER28901.1 - 1.9e-30 105.9 1.4 1.9e-30 105.9 1.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EER28901.1 - 1.1e-23 83.9 0.5 2.3e-23 82.9 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EER28901.1 - 4.5e-17 61.3 0.1 9.9e-17 60.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EER28901.1 - 1.6e-15 57.5 4.0 2.5e-15 56.8 0.6 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF134 PF02001.11 EER28901.1 - 0.055 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF134 INCENP_ARK-bind PF03941.10 EER28902.1 - 1.6e-17 63.1 0.4 5.6e-17 61.3 0.1 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region PDZ_1 PF12812.2 EER28903.1 - 2.6e-55 184.2 0.0 2.4e-35 120.2 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EER28903.1 - 4.5e-14 52.1 0.0 7.9e-05 22.4 0.0 3.9 3 0 0 3 3 3 3 PDZ domain Trypsin_2 PF13365.1 EER28903.1 - 6.7e-14 51.9 0.0 2e-13 50.3 0.0 1.9 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ PF00595.19 EER28903.1 - 1.4e-11 44.3 0.1 4.2e-05 23.6 0.0 3.9 4 0 0 4 4 4 3 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EER28903.1 - 4.7e-05 23.0 0.0 0.00017 21.2 0.0 1.9 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EER28903.1 - 0.0038 16.9 0.1 0.88 9.4 0.0 3.6 3 0 0 3 3 3 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EER28903.1 - 0.073 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EER28903.1 - 0.12 11.6 0.2 0.18 11.1 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 EER28903.1 - 0.2 10.0 0.4 0.36 9.1 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 SSXT PF05030.7 EER28904.1 - 4.2e-05 23.0 0.0 0.25 10.9 0.0 2.7 2 0 0 2 2 2 2 SSXT protein (N-terminal region) Fungal_trans PF04082.13 EER28905.1 - 1.2e-15 57.1 5.2 1e-13 50.7 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28905.1 - 5.9e-05 22.8 11.0 0.00012 21.8 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_11 PF13414.1 EER28906.1 - 9.2e-12 44.4 5.5 1.2e-08 34.4 0.1 3.0 2 2 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EER28906.1 - 5.6e-11 41.4 5.1 0.011 15.5 0.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EER28906.1 - 6.8e-10 38.1 5.6 0.00038 19.9 0.2 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EER28906.1 - 0.0011 19.0 1.5 0.0033 17.5 1.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EER28906.1 - 0.003 18.1 0.2 0.003 18.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 EER28906.1 - 0.0044 17.3 0.8 0.0044 17.3 0.6 1.8 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_17 PF13431.1 EER28906.1 - 0.016 15.3 0.7 0.2 11.9 0.1 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EER28906.1 - 0.056 13.2 2.1 17 5.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EER28906.1 - 0.32 11.7 4.6 0.74 10.6 0.3 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Lipoprotein_20 PF13942.1 EER28907.1 - 0.11 11.9 4.8 0.23 10.9 3.3 1.6 1 1 0 1 1 1 0 YfhG lipoprotein XLF PF09302.6 EER28907.1 - 1.7 8.3 6.0 3.1 7.5 4.1 1.5 1 1 0 1 1 1 0 XLF (XRCC4-like factor) peroxidase PF00141.18 EER28908.1 - 5.7e-46 156.8 0.0 8.3e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Pyridoxal_deC PF00282.14 EER28910.1 - 2.5e-79 266.4 0.0 3.9e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain N2227 PF07942.7 EER28911.1 - 1.4e-52 178.3 0.0 2.2e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EER28911.1 - 0.00046 19.9 0.0 0.001 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER28911.1 - 0.00047 20.5 0.0 0.0016 18.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER28911.1 - 0.001 19.5 0.0 0.0028 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER28911.1 - 0.0057 16.6 0.0 0.024 14.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER28911.1 - 0.0079 16.7 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EER28913.1 - 3.4e-20 72.9 1.0 5.4e-20 72.2 0.7 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER28913.1 - 9.9e-14 51.4 0.0 1.4e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER28913.1 - 2.1e-05 24.3 0.0 4.3e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER28913.1 - 0.063 12.4 0.0 0.95 8.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family SBDS_C PF09377.5 EER28914.1 - 6.2e-46 155.1 0.0 9.6e-46 154.5 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EER28914.1 - 7.4e-27 92.9 0.2 1.2e-26 92.3 0.1 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.17 EER28915.1 - 5.4e-132 440.8 0.1 6.7e-132 440.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EER28915.1 - 7.5e-08 32.5 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EER28915.1 - 0.11 12.2 0.0 2.4 7.9 0.0 2.7 3 1 0 3 3 3 0 Alpha/beta hydrolase family Ribosomal_S13 PF00416.17 EER28916.1 - 9.3e-42 141.8 2.8 1.1e-41 141.5 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EER28916.1 - 0.016 13.7 0.0 0.016 13.7 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EER28916.1 - 0.1 12.6 0.4 0.33 11.0 0.0 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif p450 PF00067.17 EER28918.1 - 1.4e-52 178.8 0.0 1.7e-52 178.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2237 PF09996.4 EER28919.1 - 0.1 12.0 0.1 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) Cytochrom_B561 PF03188.11 EER28920.1 - 4.2e-06 26.6 12.9 1.4e-05 24.9 9.0 1.9 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EER28920.1 - 0.0034 17.2 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 DOMON domain Yip1 PF04893.12 EER28920.1 - 2.6 7.5 15.4 6.8 6.1 10.7 1.6 1 0 0 1 1 1 0 Yip1 domain Abhydrolase_6 PF12697.2 EER28921.1 - 1.2e-10 41.7 0.8 2.1e-10 40.8 0.5 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER28921.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EER28921.1 - 0.0004 20.0 0.0 0.00062 19.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EER28921.1 - 0.016 14.4 0.0 0.089 12.0 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family LIP PF03583.9 EER28921.1 - 0.044 12.9 0.1 1.9 7.5 0.0 2.3 2 1 0 2 2 2 0 Secretory lipase Bul1_N PF04425.7 EER28922.1 - 1.2e-08 33.9 1.2 9.7e-08 30.9 0.8 2.3 1 1 0 1 1 1 1 Bul1 N terminus Arrestin_N PF00339.24 EER28922.1 - 1.7e-05 24.6 0.0 0.00018 21.3 0.0 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EER28922.1 - 0.0058 15.8 0.1 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Bul1 C terminus Gly_transf_sug PF04488.10 EER28923.1 - 4.4e-19 68.7 0.1 9.4e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EER28923.1 - 0.01 14.3 3.8 0.85 8.0 1.2 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain ERG4_ERG24 PF01222.12 EER28925.1 - 5.9e-146 486.3 18.0 7.4e-146 486.0 12.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EER28925.1 - 0.013 15.5 0.0 0.013 15.5 0.0 3.1 3 0 0 3 3 3 0 Phospholipid methyltransferase MamL-1 PF09596.5 EER28925.1 - 0.23 11.2 2.1 0.44 10.3 1.5 1.4 1 0 0 1 1 1 0 MamL-1 domain Fungal_trans_2 PF11951.3 EER28926.1 - 7.2e-36 123.5 0.2 1.1e-35 122.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER28926.1 - 3.4e-10 39.6 5.4 7.6e-10 38.5 3.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VIT_2 PF13757.1 EER28926.1 - 0.028 13.8 0.1 0.078 12.4 0.0 1.8 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain Abhydrolase_6 PF12697.2 EER28927.1 - 0.0018 18.2 0.1 0.0022 17.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family IGPD PF00475.13 EER28929.1 - 1.7e-53 180.3 0.1 3e-53 179.5 0.1 1.4 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF1856 PF08983.5 EER28929.1 - 2.9 8.0 5.8 0.19 11.8 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1856) LRR_6 PF13516.1 EER28930.1 - 0.00063 19.5 1.4 40 4.7 0.0 6.7 6 0 0 6 6 6 1 Leucine Rich repeat LRR_7 PF13504.1 EER28930.1 - 0.07 13.3 3.1 32 5.3 0.0 5.3 5 0 0 5 5 5 0 Leucine rich repeat Pet127 PF08634.5 EER28931.1 - 3.2e-115 384.0 0.0 4.4e-115 383.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 GARS_A PF01071.14 EER28932.1 - 9.2e-84 279.8 0.0 2.1e-83 278.7 0.0 1.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EER28932.1 - 5.8e-37 126.1 0.3 8.2e-36 122.4 0.0 3.1 4 0 0 4 4 4 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EER28932.1 - 2.6e-29 102.2 0.0 7.7e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EER28932.1 - 4.5e-27 94.0 0.3 1.2e-26 92.7 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EER28932.1 - 3.5e-17 62.4 1.6 3.5e-17 62.4 1.1 2.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EER28932.1 - 1.6e-09 37.7 0.0 1.4e-08 34.6 0.0 2.4 2 1 1 3 3 3 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EER28932.1 - 7.2e-09 34.8 0.0 1.5e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EER28932.1 - 6.2e-07 28.9 0.0 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EER28932.1 - 5.4e-05 23.1 0.0 0.00027 20.8 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EER28932.1 - 0.00016 21.0 0.0 0.00043 19.6 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EER28932.1 - 0.0087 15.5 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 EER28932.1 - 0.044 13.1 0.0 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Glyco_hydro_18 PF00704.23 EER28933.1 - 1.9e-93 313.6 9.5 2.2e-93 313.4 6.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Grp1_Fun34_YaaH PF01184.14 EER28934.1 - 6.8e-55 185.6 13.1 9.4e-55 185.1 9.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2254 PF10011.4 EER28934.1 - 0.56 8.6 4.9 0.87 7.9 3.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF3796 PF12676.2 EER28934.1 - 0.61 10.3 10.2 1.4 9.1 7.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF998 PF06197.8 EER28934.1 - 5.1 6.3 25.2 21 4.3 14.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF998) Prenyltrans PF00432.16 EER28935.1 - 1.2e-30 104.6 0.9 2.5e-10 39.7 0.0 4.0 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EER28935.1 - 5.3e-28 97.1 0.1 1e-10 41.5 0.0 5.7 3 1 3 6 6 6 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 EER28935.1 - 1.3e-24 86.7 0.0 3e-15 56.6 0.0 5.2 3 1 2 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 EER28935.1 - 4e-09 36.0 0.2 0.053 12.6 0.0 4.5 4 1 1 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 EER28935.1 - 0.00017 20.9 0.0 0.013 14.6 0.0 3.0 2 1 1 3 3 3 1 A-macroglobulin complement component Actin PF00022.14 EER28936.1 - 8.6e-160 531.4 0.0 9.8e-160 531.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EER28936.1 - 0.036 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 EER28937.1 - 6.4e-33 113.1 10.9 1.1e-32 112.3 5.2 2.2 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EER28937.1 - 5.9e-11 42.5 2.8 1.8e-10 40.9 0.1 2.3 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EER28937.1 - 5.5e-09 36.2 0.1 1.5e-06 28.5 0.0 3.0 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 EER28937.1 - 1.1e-07 31.2 0.1 0.019 15.0 0.0 2.8 2 0 0 2 2 2 2 HEAT repeat Arm PF00514.18 EER28937.1 - 2.6e-06 27.0 0.0 0.073 12.9 0.0 2.6 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 EER28937.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.15 EER28937.1 - 0.0025 16.2 0.1 0.0043 15.4 0.0 1.3 1 1 0 1 1 1 1 Adaptin N terminal region Atx10homo_assoc PF09759.4 EER28937.1 - 0.057 13.1 0.1 0.18 11.5 0.1 1.8 1 1 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain UPF0220 PF05255.6 EER28938.1 - 5.3e-66 220.9 3.3 5.9e-66 220.7 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1049 PF06305.6 EER28938.1 - 9.9 5.7 6.5 6.2 6.3 2.4 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) BLVR PF06375.6 EER28939.1 - 0.00015 21.6 23.7 0.00015 21.6 16.4 1.0 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) BUD22 PF09073.5 EER28939.1 - 0.0011 18.1 18.6 0.0011 18.0 12.9 1.0 1 0 0 1 1 1 1 BUD22 FAM176 PF14851.1 EER28939.1 - 0.0054 16.4 4.8 0.0056 16.3 3.3 1.1 1 0 0 1 1 1 1 FAM176 family DUF1510 PF07423.6 EER28939.1 - 0.021 14.2 16.3 0.022 14.1 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) FLO_LFY PF01698.11 EER28939.1 - 0.12 11.2 14.7 0.12 11.1 10.2 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Otopetrin PF03189.8 EER28939.1 - 0.25 10.2 3.8 0.27 10.2 2.6 1.0 1 0 0 1 1 1 0 Otopetrin STAG PF08514.6 EER28939.1 - 0.32 10.6 7.5 0.42 10.3 5.2 1.3 1 0 0 1 1 1 0 STAG domain SID-1_RNA_chan PF13965.1 EER28939.1 - 0.39 8.8 1.6 0.38 8.8 1.1 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 eIF3_subunit PF08597.5 EER28939.1 - 0.46 10.0 26.0 0.53 9.8 18.0 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Peroxin-13_N PF04088.8 EER28939.1 - 0.49 10.3 6.4 0.5 10.2 4.4 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Bap31 PF05529.7 EER28939.1 - 0.65 9.4 10.1 0.65 9.4 7.0 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF755 PF05501.6 EER28939.1 - 0.8 9.7 17.5 0.83 9.7 12.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF3537 PF12056.3 EER28939.1 - 0.85 8.2 2.4 0.89 8.1 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Folate_carrier PF01770.13 EER28939.1 - 0.87 8.0 4.2 0.8 8.1 2.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier FHIPEP PF00771.15 EER28939.1 - 0.88 7.8 2.7 0.84 7.8 1.9 1.1 1 0 0 1 1 1 0 FHIPEP family DUF1168 PF06658.7 EER28939.1 - 0.99 8.9 30.3 1.1 8.7 21.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) GAGA_bind PF06217.7 EER28939.1 - 1 9.2 16.4 1 9.2 11.4 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIF_alpha PF05793.7 EER28939.1 - 1.1 7.5 29.8 1.3 7.3 20.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) BTV_NS2 PF04514.7 EER28939.1 - 1.4 7.6 15.2 1.5 7.6 10.5 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF3987 PF13148.1 EER28939.1 - 1.5 7.2 16.8 1.7 7.1 11.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) CDC45 PF02724.9 EER28939.1 - 1.5 6.7 12.2 1.7 6.5 8.4 1.0 1 0 0 1 1 1 0 CDC45-like protein AIF_C PF14721.1 EER28939.1 - 1.9 8.7 8.4 2.1 8.5 5.8 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rtf2 PF04641.7 EER28939.1 - 2 7.5 21.7 2.4 7.2 15.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF2457 PF10446.4 EER28939.1 - 2 7.0 18.8 2.2 6.8 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Oleosin PF01277.12 EER28939.1 - 2.1 7.9 5.7 2.6 7.6 3.9 1.1 1 0 0 1 1 1 0 Oleosin RNA_pol_3_Rpc31 PF11705.3 EER28939.1 - 2.7 7.8 18.7 3.2 7.6 13.0 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 RabGAP-TBC PF00566.13 EER28939.1 - 2.7 7.3 9.4 3.1 7.2 6.5 1.2 1 0 0 1 1 1 0 Rab-GTPase-TBC domain RP-C_C PF11800.3 EER28939.1 - 3.2 7.3 6.0 3.2 7.3 4.2 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region LicD PF04991.8 EER28939.1 - 3.5 7.6 11.1 3.6 7.6 7.7 1.0 1 0 0 1 1 1 0 LicD family DUF1675 PF07897.6 EER28939.1 - 3.6 7.3 10.3 4.2 7.1 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Paramyxo_ncap PF00973.14 EER28939.1 - 3.7 6.1 8.7 3.7 6.1 6.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SHR3_chaperone PF08229.6 EER28939.1 - 3.8 6.4 12.1 4.3 6.2 8.4 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 Serinc PF03348.10 EER28939.1 - 4.2 5.9 5.7 4.4 5.9 3.9 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pex24p PF06398.6 EER28939.1 - 4.5 5.9 6.8 4.4 5.9 4.7 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Agouti PF05039.7 EER28939.1 - 4.9 7.5 8.1 6.4 7.2 5.6 1.3 1 0 0 1 1 1 0 Agouti protein Gti1_Pac2 PF09729.4 EER28939.1 - 5 6.9 11.0 6 6.7 7.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Conotoxin PF02950.12 EER28939.1 - 5.3 7.9 9.7 20 6.0 6.7 1.8 1 1 0 1 1 1 0 Conotoxin PBP_sp32 PF07222.7 EER28939.1 - 5.4 6.1 15.3 6.2 5.9 10.6 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Pox_Ag35 PF03286.9 EER28939.1 - 6.2 6.2 25.8 7.3 6.0 17.9 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SpoVR PF04293.8 EER28939.1 - 6.2 5.0 9.6 6.6 4.9 6.6 1.0 1 0 0 1 1 1 0 SpoVR like protein TLC PF03219.9 EER28939.1 - 6.3 5.1 5.4 6.5 5.0 3.7 1.1 1 0 0 1 1 1 0 TLC ATP/ADP transporter Peptidase_U57 PF05582.7 EER28939.1 - 6.3 5.6 9.8 6.8 5.5 6.8 1.0 1 0 0 1 1 1 0 YabG peptidase U57 Bud13 PF09736.4 EER28939.1 - 6.5 7.0 22.7 7.2 6.8 15.7 1.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex SR-25 PF10500.4 EER28939.1 - 6.6 6.1 31.2 7.4 5.9 21.6 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein EIIBC-GUT_N PF03612.9 EER28939.1 - 6.8 6.2 8.1 7.2 6.1 5.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Tom22 PF04281.8 EER28939.1 - 7.1 6.1 13.0 9 5.8 9.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 AAA_11 PF13086.1 EER28939.1 - 7.1 6.1 9.5 7.2 6.1 6.6 1.0 1 0 0 1 1 1 0 AAA domain UPF0560 PF10577.4 EER28939.1 - 7.6 4.6 11.3 8.2 4.5 7.8 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ribosomal_S25 PF03297.10 EER28939.1 - 7.6 6.6 21.0 8.4 6.4 14.6 1.1 1 0 0 1 1 1 0 S25 ribosomal protein Ycf1 PF05758.7 EER28939.1 - 7.9 4.0 13.3 8.1 4.0 9.2 1.0 1 0 0 1 1 1 0 Ycf1 Cellulose_synt PF03552.9 EER28939.1 - 8.5 4.5 10.1 8.2 4.5 7.0 1.0 1 0 0 1 1 1 0 Cellulose synthase OATP PF03137.15 EER28939.1 - 8.6 4.2 6.2 8.8 4.2 4.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family RNA_pol_Rpb1_5 PF04998.12 EER28939.1 - 9.3 5.4 8.5 9.4 5.3 5.9 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DDHD PF02862.12 EER28939.1 - 9.4 5.9 11.2 10 5.8 7.8 1.0 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 EER28939.1 - 9.4 6.2 19.7 11 5.9 13.6 1.1 1 0 0 1 1 1 0 YqfQ-like protein Pkinase PF00069.20 EER28940.1 - 1.3e-28 99.8 0.0 1.8e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER28940.1 - 3.8e-25 88.4 0.0 5.3e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EER28940.1 - 1.7e-05 23.9 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EER28940.1 - 0.00035 19.6 0.0 0.00076 18.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EER28940.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family PIP49_C PF12260.3 EER28940.1 - 0.021 14.2 0.0 0.053 12.9 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Choline_kinase PF01633.15 EER28940.1 - 0.021 14.3 0.4 0.37 10.3 0.1 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase WaaY PF06176.6 EER28940.1 - 0.029 13.5 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 EER28940.1 - 0.035 13.8 0.0 0.049 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BLVR PF06375.6 EER28941.1 - 0.0011 18.7 16.3 0.0014 18.5 11.3 1.1 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) FLO_LFY PF01698.11 EER28941.1 - 0.0023 16.8 1.7 0.0023 16.8 1.2 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein Rtf2 PF04641.7 EER28941.1 - 0.018 14.2 8.3 0.021 14.0 5.7 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Protocadherin PF08374.6 EER28941.1 - 0.043 13.4 1.9 0.045 13.3 1.3 1.4 1 0 0 1 1 1 0 Protocadherin DUF2961 PF11175.3 EER28941.1 - 0.075 12.3 0.1 0.089 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) Fimbrial_PilY2 PF14481.1 EER28941.1 - 0.12 11.7 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 HA2 PF04408.18 EER28941.1 - 0.13 12.3 0.3 0.14 12.1 0.2 1.2 1 0 0 1 1 1 0 Helicase associated domain (HA2) Pox_Ag35 PF03286.9 EER28941.1 - 0.23 10.9 13.7 0.28 10.6 9.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peroxin-13_N PF04088.8 EER28941.1 - 0.74 9.7 3.2 1.2 9.1 2.2 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Eapp_C PF10238.4 EER28941.1 - 1 9.2 7.7 1.2 9.0 5.3 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein GAGA_bind PF06217.7 EER28941.1 - 1 9.2 9.7 1.1 9.1 6.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FAM176 PF14851.1 EER28941.1 - 2.1 7.9 5.2 2.6 7.7 3.6 1.2 1 0 0 1 1 1 0 FAM176 family U79_P34 PF03064.11 EER28941.1 - 2.2 7.7 11.5 2.5 7.5 8.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 EER28941.1 - 4.1 7.1 14.1 5.3 6.8 9.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.8 EER28941.1 - 6.6 7.1 7.3 12 6.3 5.1 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Rtf2 PF04641.7 EER28942.1 - 1.7e-06 27.4 1.6 1.7e-06 27.4 1.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Histone PF00125.19 EER28942.1 - 4.2e-05 23.5 0.2 6.2e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CT47 PF15623.1 EER28942.1 - 7.7e-05 22.5 5.5 8.3e-05 22.4 3.8 1.2 1 0 0 1 1 1 1 Cancer/testis gene family 47 FYDLN_acid PF09538.5 EER28942.1 - 0.068 13.7 27.0 0.11 13.1 18.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1510 PF07423.6 EER28942.1 - 0.24 10.7 27.2 0.31 10.3 18.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Cwf_Cwc_15 PF04889.7 EER28942.1 - 0.38 10.4 31.7 0.47 10.1 21.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Raftlin PF15250.1 EER28942.1 - 0.42 9.0 6.3 0.54 8.7 4.4 1.1 1 0 0 1 1 1 0 Raftlin Peroxin-13_N PF04088.8 EER28942.1 - 0.71 9.8 2.8 1.1 9.1 1.9 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FLO_LFY PF01698.11 EER28942.1 - 0.72 8.6 15.9 0.95 8.2 11.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 EER28942.1 - 0.72 9.6 7.1 0.88 9.3 4.9 1.2 1 0 0 1 1 1 0 DDHD domain BUD22 PF09073.5 EER28942.1 - 0.9 8.5 31.3 1.2 8.1 21.7 1.0 1 0 0 1 1 1 0 BUD22 Pox_Ag35 PF03286.9 EER28942.1 - 1.1 8.7 25.9 1.7 8.1 18.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GAGA_bind PF06217.7 EER28942.1 - 1.9 8.4 12.6 2.3 8.0 8.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Ycf1 PF05758.7 EER28942.1 - 2.6 5.6 19.4 3.3 5.3 13.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF2514 PF10721.4 EER28942.1 - 2.6 7.7 10.3 3.8 7.1 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Nop53 PF07767.6 EER28942.1 - 2.9 6.8 29.1 3.5 6.5 20.2 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RNA_pol_3_Rpc31 PF11705.3 EER28942.1 - 3.2 7.6 33.5 4.9 7.0 23.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF1168 PF06658.7 EER28942.1 - 4 6.9 29.6 5.5 6.5 20.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) U79_P34 PF03064.11 EER28942.1 - 4.5 6.7 20.0 5.8 6.3 13.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3987 PF13148.1 EER28942.1 - 6 5.3 12.3 8.6 4.7 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2457 PF10446.4 EER28942.1 - 8.5 4.9 42.0 12 4.5 29.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Zip PF02535.17 EER28942.1 - 9.2 5.1 8.0 14 4.5 5.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ASL_C PF08328.6 EER28943.1 - 0.066 13.0 0.3 0.5 10.2 0.2 2.1 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminal Vps55 PF04133.9 EER28944.1 - 4.9e-44 148.9 5.5 5.4e-44 148.7 3.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.21 EER28945.1 - 3.5e-52 176.4 0.1 4.4e-52 176.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EER28945.1 - 7e-12 44.4 0.3 1.4e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 EER28945.1 - 0.019 14.6 0.4 22 4.8 0.0 3.2 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK PTSIIA_gutA PF03829.8 EER28945.1 - 0.091 12.4 0.0 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component Lysine_decarbox PF03641.9 EER28946.1 - 2e-31 108.5 0.0 4.3e-31 107.4 0.0 1.6 1 1 0 1 1 1 1 Possible lysine decarboxylase Med6 PF04934.9 EER28947.1 - 4.2e-43 146.2 0.0 5.8e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component RdRP PF05183.7 EER28948.1 - 1.2e-163 545.9 0.0 1.6e-163 545.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_6 PF14259.1 EER28948.1 - 0.053 13.4 0.0 0.19 11.7 0.0 2.1 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Chorismate_bind PF00425.13 EER28949.1 - 2.7e-16 59.6 0.1 1.5e-15 57.2 0.1 2.0 1 1 0 1 1 1 1 chorismate binding enzyme CtIP_N PF10482.4 EER28949.1 - 0.018 14.8 3.9 1.9 8.2 0.8 2.8 3 0 0 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain Herpes_LMP1 PF05297.6 EER28949.1 - 0.065 12.1 0.1 0.1 11.4 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) HisKA PF00512.20 EER28950.1 - 0.031 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF3684 PF12449.3 EER28951.1 - 0 1453.9 0.0 0 1453.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EER28951.1 - 0.00011 21.8 0.0 0.00026 20.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EER28951.1 - 0.009 15.7 0.0 0.024 14.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 60KD_IMP PF02096.15 EER28951.1 - 0.1 12.2 0.5 0.2 11.2 0.3 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein TRAPPC9-Trs120 PF08626.6 EER28952.1 - 1e-142 476.9 0.0 1.7e-142 476.1 0.0 1.4 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Abhydrolase_6 PF12697.2 EER28953.1 - 4.6e-14 52.8 0.0 6.6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER28953.1 - 3.3e-11 43.1 0.0 7.7e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER28953.1 - 4.1e-06 26.6 0.0 9e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EER28953.1 - 0.017 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase phage_tail_N PF08400.5 EER28954.1 - 0.069 12.8 0.3 0.2 11.3 0.2 1.8 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Complex1_LYR_2 PF13233.1 EER28955.1 - 3.5e-06 27.4 0.7 4.7e-06 27.0 0.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EER28955.1 - 1.5e-05 24.7 0.5 3.1e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EER28955.1 - 0.00012 22.1 0.4 0.00022 21.3 0.3 1.5 1 0 0 1 1 1 1 Complex1_LYR-like RNA_pol_L_2 PF13656.1 EER28956.1 - 4.7e-31 106.0 0.0 6.6e-31 105.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EER28956.1 - 2e-12 46.0 0.0 2.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Peptidase_M22 PF00814.20 EER28957.1 - 5.1e-85 285.2 0.0 6.1e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Rubis-subs-bind PF09273.6 EER28958.1 - 8.7e-13 48.2 0.5 2.4e-12 46.8 0.3 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EER28958.1 - 3.9e-10 40.2 0.0 1.2e-09 38.6 0.0 1.8 1 1 0 1 1 1 1 SET domain EPL1 PF10513.4 EER28959.1 - 8.3e-33 113.8 1.1 8.3e-33 113.8 0.7 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 EER28960.1 - 9e-25 84.0 12.9 5.5e-07 28.4 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EER28960.1 - 5.2e-20 71.3 5.9 1.9e-11 43.8 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EER28960.1 - 1e-18 65.4 5.6 0.00013 21.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EER28960.1 - 1.2e-17 62.3 14.2 1.2e-06 27.5 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EER28960.1 - 1.2e-13 50.3 14.4 1.1e-05 24.9 0.6 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EER28960.1 - 1.9e-06 27.8 0.1 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EER28960.1 - 7.8e-06 25.5 10.2 0.02 14.6 0.1 3.9 1 1 3 4 4 4 4 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EER28960.1 - 0.09 12.7 0.0 1.8 8.5 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.14 EER28963.1 - 2e-37 128.1 0.1 2.8e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EER28964.1 - 9.5e-47 157.1 0.0 1.7e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EER28964.1 - 5.7e-13 48.6 0.0 1.4e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EER28964.1 - 9.2e-10 38.6 0.0 2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER28964.1 - 2.6e-09 36.8 0.0 7.9e-09 35.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EER28964.1 - 2.6e-07 30.7 0.0 8.3e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EER28964.1 - 3.9e-05 24.0 0.1 0.00012 22.5 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EER28964.1 - 0.0012 18.7 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Spy1 PF11357.3 EER28964.1 - 0.091 12.8 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Cell cycle regulatory protein NIF PF03031.13 EER28965.1 - 2.3e-24 85.8 0.1 3.6e-24 85.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Condensation PF00668.15 EER28965.1 - 0.2 10.4 1.5 0.29 9.9 1.0 1.2 1 0 0 1 1 1 0 Condensation domain Peptidase_S49_N PF08496.5 EER28965.1 - 0.95 9.2 3.3 1.6 8.4 2.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF947 PF06102.7 EER28966.1 - 1.1e-43 148.9 15.5 1.1e-43 148.9 10.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF947) DnaG_DnaB_bind PF08278.6 EER28966.1 - 5.7 7.1 8.2 2.2 8.5 1.3 2.7 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding NAD_binding_2 PF03446.10 EER28968.1 - 1.2e-23 83.6 0.0 2.9e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EER28968.1 - 1.1e-10 41.6 0.1 2.5e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF1757 PF08560.5 EER28970.1 - 4.3e-09 36.2 0.0 5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) DUF3021 PF11457.3 EER28970.1 - 0.085 12.7 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Abhydrolase_6 PF12697.2 EER28971.1 - 4.6e-25 88.8 0.0 5.5e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER28971.1 - 7.8e-17 61.5 0.0 4.8e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER28971.1 - 2e-12 47.0 0.0 6.4e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EER28971.1 - 0.0004 19.8 0.0 0.0095 15.3 0.0 2.6 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.9 EER28971.1 - 0.0058 15.1 0.0 0.026 13.0 0.0 1.8 1 1 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.16 EER28971.1 - 0.0064 15.7 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family PhoPQ_related PF10142.4 EER28971.1 - 0.0075 14.7 0.0 0.014 13.9 0.0 1.3 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_4 PF08386.5 EER28971.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein AMPKBI PF04739.10 EER28972.1 - 1.6e-28 98.5 0.1 4e-28 97.2 0.1 1.7 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 EER28972.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Mannosyl_trans3 PF11051.3 EER28973.1 - 3.8e-77 259.2 0.0 1e-76 257.8 0.0 1.7 1 1 0 1 1 1 1 Mannosyltransferase putative ABC1 PF03109.11 EER28974.1 - 3.7e-33 114.0 0.0 8.6e-33 112.8 0.0 1.7 1 0 0 1 1 1 1 ABC1 family UreF PF01730.11 EER28975.1 - 1.5e-13 51.0 0.8 1.1e-12 48.3 0.5 2.0 1 1 0 1 1 1 1 UreF BRE1 PF08647.6 EER28976.1 - 6.7e-28 96.5 12.4 6.7e-28 96.5 8.6 6.8 3 2 3 6 6 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EER28976.1 - 1e-08 35.0 10.3 1.7e-08 34.3 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER28976.1 - 9.7e-08 31.5 10.3 1.7e-07 30.7 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER28976.1 - 1.6e-07 30.8 7.9 2.7e-07 30.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER28976.1 - 3.1e-06 26.8 8.5 6.3e-06 25.9 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EER28976.1 - 5.9e-05 22.7 10.3 0.0001 21.9 7.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EER28976.1 - 0.00032 20.3 5.5 0.00093 18.8 3.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger DUF745 PF05335.8 EER28976.1 - 0.00035 20.1 7.8 0.00035 20.1 5.4 5.9 3 2 3 6 6 6 1 Protein of unknown function (DUF745) Reo_sigmaC PF04582.7 EER28976.1 - 0.00086 18.5 3.9 0.00086 18.5 2.7 5.3 2 2 3 5 5 5 2 Reovirus sigma C capsid protein PspA_IM30 PF04012.7 EER28976.1 - 0.0014 18.0 11.0 0.0014 18.0 7.6 6.1 2 1 3 5 5 3 1 PspA/IM30 family zf-rbx1 PF12678.2 EER28976.1 - 0.0071 16.4 3.3 0.024 14.7 2.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger CENP-F_leu_zip PF10473.4 EER28976.1 - 0.02 14.7 80.7 0.056 13.3 7.3 6.9 3 1 4 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-C3HC4_4 PF15227.1 EER28976.1 - 0.024 14.5 6.4 0.045 13.6 4.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EER28976.1 - 0.029 13.9 7.0 0.076 12.6 4.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EER28976.1 - 0.051 13.4 6.0 0.11 12.3 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 EER28976.1 - 0.075 12.5 3.3 0.17 11.4 2.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Syntaxin PF00804.20 EER28976.1 - 0.084 13.0 0.3 0.084 13.0 0.2 6.6 3 1 2 5 5 4 0 Syntaxin zf-RING_6 PF14835.1 EER28976.1 - 0.17 11.7 3.0 0.33 10.7 2.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 EER28976.1 - 5.5 6.9 11.1 1.3e+02 2.6 0.3 2.5 1 1 1 2 2 2 0 FYVE zinc finger Myb_DNA-binding PF00249.26 EER28977.1 - 1.2e-06 28.4 0.0 3.1e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF1183 PF06682.7 EER28978.1 - 1.6e-78 264.5 15.5 1.6e-77 261.2 10.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) BTB_2 PF02214.17 EER28979.1 - 2.2e-06 27.7 0.0 3.9e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EER28979.1 - 3.3e-05 23.8 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain DUF2404 PF10296.4 EER28980.1 - 2.2e-05 24.4 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 EER28981.1 - 3.8e-46 156.8 0.1 4.6e-46 156.6 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EER28981.1 - 1.8e-09 36.9 0.2 2.9e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EER28981.1 - 0.0002 21.0 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EER28981.1 - 0.0042 16.5 0.0 0.0057 16.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EER28981.1 - 0.02 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GIDA PF01134.17 EER28982.1 - 2.2e-154 514.0 0.0 2.8e-154 513.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EER28982.1 - 5.4e-20 71.2 0.0 3.6e-19 68.6 0.0 2.4 2 0 0 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EER28982.1 - 2.5e-07 30.7 0.4 6.4e-07 29.4 0.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EER28982.1 - 1e-06 28.1 0.5 1.9e-06 27.2 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EER28982.1 - 1.7e-05 23.8 1.7 0.055 12.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EER28982.1 - 0.00081 18.3 2.2 0.00081 18.3 1.5 1.7 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EER28982.1 - 0.001 18.6 0.1 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EER28982.1 - 0.026 13.0 0.7 0.21 10.0 0.3 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.1 EER28982.1 - 0.075 13.0 0.0 0.28 11.1 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EER28982.1 - 0.22 10.1 0.3 6.9 5.1 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.11 EER28983.1 - 6.3e-40 136.9 29.8 2.3e-39 135.1 20.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EER28983.1 - 9.3e-20 70.3 10.8 1.2e-19 69.9 7.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER28983.1 - 1.5e-17 63.3 11.6 1.5e-17 63.3 8.0 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EER28983.1 - 0.0072 14.4 1.5 0.016 13.2 0.2 1.9 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CDP-OH_P_transf PF01066.16 EER28984.1 - 4.1e-18 65.5 4.8 7.9e-18 64.6 3.4 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase APH PF01636.18 EER28985.1 - 2.4e-09 37.3 0.0 1.5e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER28985.1 - 0.037 13.5 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EER28985.1 - 0.084 11.9 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase DUF1679 PF07914.6 EER28985.1 - 0.19 10.2 0.0 0.29 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) HNH_2 PF13391.1 EER28986.1 - 2.8e-13 49.4 0.1 6.2e-13 48.3 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease Gti1_Pac2 PF09729.4 EER28987.1 - 1.1e-62 210.7 0.0 1.4e-62 210.4 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family Tyr-DNA_phospho PF06087.7 EER28988.1 - 5.8e-57 193.2 0.0 3.1e-44 151.3 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 EER28988.1 - 0.00057 19.2 0.1 0.00057 19.2 0.1 3.4 3 0 0 3 3 3 1 Ubiquitin interaction motif PLDc_2 PF13091.1 EER28988.1 - 0.0018 18.0 0.0 0.014 15.1 0.0 2.3 2 0 0 2 2 2 1 PLD-like domain Pkinase PF00069.20 EER28990.1 - 1.3e-26 93.3 0.0 6.6e-25 87.7 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER28990.1 - 1.6e-11 43.8 0.0 2.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Myb_DNA-binding PF00249.26 EER28991.1 - 0.00013 21.9 0.2 0.00025 21.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain NAD_binding_8 PF13450.1 EER28992.1 - 8e-12 45.0 0.1 2.3e-11 43.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EER28992.1 - 7.8e-10 38.1 0.0 7.8e-07 28.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EER28992.1 - 2.6e-07 30.7 0.0 0.0012 18.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EER28992.1 - 8.9e-06 24.7 1.2 1.5e-05 24.0 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EER28992.1 - 1.1e-05 24.1 0.9 6.5e-05 21.5 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EER28992.1 - 7e-05 23.1 0.2 0.11 12.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER28992.1 - 0.00021 21.4 0.1 0.00039 20.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EER28992.1 - 0.00032 19.9 0.1 0.014 14.4 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 EER28992.1 - 0.00034 19.7 0.0 0.0006 18.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EER28992.1 - 0.00074 19.3 0.1 0.0036 17.0 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EER28992.1 - 0.0022 17.1 0.0 0.027 13.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EER28992.1 - 0.0029 16.3 0.0 0.0051 15.5 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EER28992.1 - 0.0091 14.9 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 EER28992.1 - 0.044 13.2 0.0 0.76 9.2 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Malic_M PF03949.10 EER28992.1 - 0.052 13.1 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain ThiF PF00899.16 EER28992.1 - 0.082 12.7 0.6 0.35 10.6 0.2 2.0 2 0 0 2 2 2 0 ThiF family FAD_binding_3 PF01494.14 EER28992.1 - 0.095 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EER28992.1 - 0.13 11.0 0.1 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A adh_short PF00106.20 EER28993.1 - 3.8e-21 75.7 0.0 5.1e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER28993.1 - 3.8e-12 46.2 0.0 5.7e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EER28993.1 - 3.1e-06 26.7 0.0 5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EER28993.1 - 0.00021 20.2 0.0 0.00042 19.3 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EER28993.1 - 0.0014 17.5 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EER28993.1 - 0.0027 16.4 0.0 0.0039 15.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EER28993.1 - 0.0031 17.5 0.1 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EER28993.1 - 0.0053 16.0 0.0 0.0091 15.2 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 EER28993.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sec1 PF00995.18 EER28994.1 - 2.3e-151 505.2 0.1 2.7e-151 505.0 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_tran_WecB PF03808.8 EER28994.1 - 0.15 11.4 0.0 10 5.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family MBOAT PF03062.14 EER28995.1 - 1.3e-47 162.4 2.9 2.4e-47 161.6 2.0 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family FAD_binding_4 PF01565.18 EER28997.1 - 1.5e-29 102.2 0.5 2.6e-29 101.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EER28997.1 - 0.00097 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Na_Ca_ex PF01699.19 EER28998.1 - 0.014 15.0 1.1 0.014 15.0 0.8 2.9 2 1 1 3 3 3 0 Sodium/calcium exchanger protein Abi PF02517.11 EER28999.1 - 2.8e-12 46.5 14.1 2.8e-12 46.5 9.7 2.7 2 1 1 3 3 3 1 CAAX protease self-immunity Suc_Fer-like PF06999.7 EER29000.1 - 1.5e-48 165.8 0.0 1.8e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like tRNA-synt_1 PF00133.17 EER29001.1 - 1.6e-56 191.5 0.0 4.9e-37 127.2 0.2 6.3 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EER29001.1 - 3.7e-38 130.6 0.0 6.2e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EER29001.1 - 1.2e-31 109.7 0.0 3.5e-24 85.2 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EER29001.1 - 8.3e-17 61.3 0.0 1.5e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EER29001.1 - 0.0014 17.8 0.0 0.055 12.5 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EER29001.1 - 0.0033 16.2 0.1 0.008 15.0 0.0 1.5 1 1 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 EER29001.1 - 0.053 12.1 0.1 6.7 5.2 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain 2-Hacid_dh_C PF02826.14 EER29003.1 - 6.7e-50 168.6 0.0 1e-49 168.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EER29003.1 - 1.1e-15 57.2 0.0 1.6e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EER29003.1 - 0.012 15.4 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sensor PF13796.1 EER29005.1 - 0.011 15.3 0.2 0.017 14.7 0.2 1.2 1 0 0 1 1 1 0 Putative sensor FH2 PF02181.18 EER29006.1 - 2.2e-80 270.3 4.7 2.2e-80 270.3 3.3 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EER29006.1 - 2.2e-70 235.8 0.5 1.4e-69 233.2 0.0 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EER29006.1 - 1.1e-51 175.0 6.5 2.2e-51 174.0 0.2 3.2 2 1 1 3 3 3 2 Diaphanous FH3 Domain PalH PF08733.5 EER29007.1 - 0.091 11.5 5.6 0.067 12.0 0.5 2.1 1 1 1 2 2 2 0 PalH/RIM21 FA_hydroxylase PF04116.8 EER29008.1 - 7.2e-16 58.6 17.8 7.2e-16 58.6 12.4 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.11 EER29009.1 - 6.3e-28 97.5 29.9 6.3e-28 97.5 20.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3267 PF11667.3 EER29009.1 - 0.046 13.9 0.1 0.046 13.9 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3267) PDGLE PF13190.1 EER29009.1 - 0.075 12.7 1.8 0.33 10.6 0.0 2.8 2 0 0 2 2 2 0 PDGLE domain DUF3302 PF11742.3 EER29009.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3302) cobW PF02492.14 EER29010.1 - 1.1e-48 165.0 3.4 4.5e-46 156.5 2.4 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EER29010.1 - 2.9e-20 71.7 0.2 4.1e-15 55.2 0.0 2.9 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EER29010.1 - 0.016 14.9 0.0 0.052 13.2 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EER29010.1 - 0.025 14.7 0.1 0.089 12.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EER29010.1 - 0.033 14.0 0.0 0.074 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EER29010.1 - 0.056 13.0 0.1 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EER29010.1 - 0.068 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EER29010.1 - 0.086 12.8 0.3 0.25 11.3 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 EER29010.1 - 0.095 11.4 0.2 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EER29010.1 - 0.096 13.0 0.0 0.096 13.0 0.0 3.1 3 1 1 4 4 4 0 AAA domain CDC45 PF02724.9 EER29010.1 - 2.6 5.9 12.5 0.0096 14.0 0.8 2.1 2 0 0 2 2 2 0 CDC45-like protein AAA_23 PF13476.1 EER29010.1 - 2.8 8.2 0.0 2.8 8.2 0.0 3.4 2 1 0 3 3 2 0 AAA domain TrmE_N PF10396.4 EER29011.1 - 4e-36 123.4 0.0 8.7e-36 122.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EER29011.1 - 1e-18 67.4 0.7 6.1e-18 64.9 0.3 2.5 2 1 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EER29011.1 - 9.2e-16 57.8 0.0 1.7e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EER29011.1 - 6.5e-06 26.0 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.22 EER29011.1 - 1.5e-05 24.5 0.1 0.0063 15.9 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EER29011.1 - 5.9e-05 22.3 0.0 0.00047 19.4 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EER29011.1 - 0.0015 19.0 0.0 0.004 17.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EER29011.1 - 0.16 12.2 0.1 0.16 12.2 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Aconitase PF00330.15 EER29012.1 - 2.5e-70 237.2 0.3 5.6e-45 153.6 0.0 2.6 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EER29012.1 - 5.6e-24 84.7 0.0 1.1e-23 83.7 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aminotran_5 PF00266.14 EER29013.1 - 1.6e-28 99.5 0.0 6.6e-19 67.8 0.0 2.1 1 1 0 2 2 2 2 Aminotransferase class-V FAD_binding_6 PF00970.19 EER29014.1 - 2e-08 34.2 0.0 1.7e-07 31.2 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EER29014.1 - 1.8e-06 28.4 0.0 7e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EER29014.1 - 0.034 14.0 0.0 0.063 13.1 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain UCR_Fe-S_N PF10399.4 EER29014.1 - 0.085 12.0 0.1 0.27 10.4 0.0 1.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal AA_permease_2 PF13520.1 EER29015.1 - 2e-64 217.7 44.4 2.7e-64 217.2 30.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER29015.1 - 1.8e-26 92.5 29.7 1.8e-26 92.5 20.6 2.0 2 0 0 2 2 2 1 Amino acid permease Methyltransf_26 PF13659.1 EER29017.1 - 1.3e-10 41.3 0.0 9.7e-10 38.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER29017.1 - 1.9e-09 37.2 0.0 5.9e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER29017.1 - 2.5e-09 37.6 0.0 7e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EER29017.1 - 5.1e-06 25.9 0.0 0.00039 19.8 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EER29017.1 - 0.0006 20.1 0.0 0.002 18.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_10 PF05971.7 EER29017.1 - 0.0028 16.8 0.0 0.03 13.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF890) UPF0020 PF01170.13 EER29017.1 - 0.0028 17.2 0.0 1.2 8.7 0.0 2.6 3 0 0 3 3 3 2 Putative RNA methylase family UPF0020 PrmA PF06325.8 EER29017.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EER29017.1 - 0.019 15.4 0.0 0.054 13.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EER29017.1 - 0.022 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AviRa PF11599.3 EER29017.1 - 0.035 13.1 0.1 0.069 12.1 0.1 1.5 1 1 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_11 PF08241.7 EER29017.1 - 0.15 12.6 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPR_14 PF13428.1 EER29017.1 - 1.7 9.4 4.9 93 4.0 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Asp PF00026.18 EER29018.1 - 1.1e-70 238.4 0.0 1.3e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EER29018.1 - 3.6e-12 46.5 0.0 9.7e-10 38.6 0.0 2.9 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EER29018.1 - 2.5e-06 27.8 0.2 0.0092 16.4 0.0 3.5 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EER29018.1 - 4.1e-05 23.1 0.0 8.1e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Git3_C PF11970.3 EER29019.1 - 0.071 12.8 0.1 0.071 12.8 0.1 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DNA_pol3_delta2 PF13177.1 EER29020.1 - 1.8e-11 43.9 0.0 1.7e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EER29020.1 - 2e-10 40.9 0.0 3.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EER29020.1 - 4.4e-07 29.8 0.0 7.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EER29020.1 - 1.8e-06 27.2 0.0 6.6e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EER29020.1 - 5.5e-06 26.4 0.1 0.00038 20.4 0.0 2.7 1 1 2 3 3 3 1 AAA ATPase domain Rad17 PF03215.10 EER29020.1 - 1.7e-05 23.7 0.0 0.038 12.6 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EER29020.1 - 5.1e-05 22.8 0.0 7.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EER29020.1 - 6.9e-05 22.9 0.1 0.0077 16.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EER29020.1 - 0.00072 19.0 0.1 0.1 12.0 0.0 2.2 1 1 0 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 EER29020.1 - 0.0011 18.5 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.1 EER29020.1 - 0.0012 18.3 0.2 0.25 10.6 0.0 3.5 2 2 1 4 4 4 1 AAA domain AAA_3 PF07726.6 EER29020.1 - 0.0016 18.0 0.0 0.0037 16.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 EER29020.1 - 0.0018 17.4 0.0 0.021 13.9 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DEAD PF00270.24 EER29020.1 - 0.0025 17.3 0.1 0.13 11.7 0.0 2.4 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.1 EER29020.1 - 0.0034 17.0 0.0 0.0096 15.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EER29020.1 - 0.0046 17.2 0.0 0.0085 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EER29020.1 - 0.0052 16.3 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EER29020.1 - 0.0098 15.1 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 SAGA-Tad1 PF12767.2 EER29020.1 - 0.011 15.3 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit NTPase_1 PF03266.10 EER29020.1 - 0.015 15.0 0.2 0.055 13.1 0.1 1.8 1 1 1 2 2 2 0 NTPase ArgK PF03308.11 EER29020.1 - 0.029 13.1 0.0 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Rep_fac_C PF08542.6 EER29020.1 - 0.04 13.9 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Replication factor C C-terminal domain AAA_5 PF07728.9 EER29020.1 - 0.042 13.5 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 EER29020.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EER29020.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EER29020.1 - 0.13 11.7 0.1 1.1 8.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain His_Phos_2 PF00328.17 EER29021.1 - 8.7e-09 35.1 0.0 2.4e-08 33.7 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Polysacc_deac_1 PF01522.16 EER29022.1 - 4.3e-23 81.2 0.0 8.8e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Parvo_coat PF00740.13 EER29022.1 - 0.017 14.1 0.7 0.023 13.6 0.5 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 DUF2334 PF10096.4 EER29022.1 - 0.024 14.0 0.0 0.1 11.9 0.0 2.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2334) Amidase PF01425.16 EER29023.1 - 3.5e-100 335.9 0.0 4.6e-100 335.5 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF410 PF04190.8 EER29025.1 - 7.7e-46 156.7 0.0 9.2e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) HTH_16 PF12645.2 EER29025.1 - 0.026 14.4 0.0 0.069 13.0 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1028 PF06267.7 EER29025.1 - 0.05 13.0 0.6 0.088 12.2 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF1028) RAI1 PF08652.6 EER29026.1 - 3.9e-30 103.4 0.1 7e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease IPPT PF01715.12 EER29027.1 - 3.3e-53 180.2 0.2 5.2e-52 176.3 0.1 2.1 1 1 0 1 1 1 1 IPP transferase AAA_33 PF13671.1 EER29027.1 - 7.7e-06 25.8 0.0 0.14 12.0 0.0 3.7 2 1 0 2 2 2 2 AAA domain zf-met PF12874.2 EER29027.1 - 9.5e-05 22.4 0.0 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_17 PF13207.1 EER29027.1 - 0.0011 19.8 1.8 0.0098 16.7 0.2 3.1 2 1 0 2 2 2 1 AAA domain IPT PF01745.11 EER29027.1 - 0.0027 16.9 0.0 0.0091 15.1 0.0 1.8 2 0 0 2 2 2 1 Isopentenyl transferase zf-C2H2_jaz PF12171.3 EER29027.1 - 0.0057 16.7 0.1 0.012 15.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_25 PF13481.1 EER29027.1 - 0.016 14.6 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain zf-C2H2_2 PF12756.2 EER29027.1 - 0.018 15.1 1.2 0.029 14.4 0.3 1.7 2 0 0 2 2 1 0 C2H2 type zinc-finger (2 copies) DUF465 PF04325.8 EER29027.1 - 0.053 13.2 0.8 3.6 7.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF465) AAA_18 PF13238.1 EER29027.1 - 0.056 13.7 2.9 1.9 8.7 1.9 3.2 1 1 0 1 1 1 0 AAA domain Lipase_GDSL_3 PF14606.1 EER29027.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family ABC_tran PF00005.22 EER29028.1 - 2.2e-16 60.3 0.2 3.2e-15 56.6 0.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EER29028.1 - 2.6e-09 37.4 2.0 0.00027 21.0 0.4 2.1 1 1 1 2 2 2 2 AAA domain AAA_29 PF13555.1 EER29028.1 - 6.3e-05 22.4 0.1 0.00015 21.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EER29028.1 - 0.00094 18.4 0.1 0.95 8.6 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EER29028.1 - 0.0067 15.5 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EER29028.1 - 0.01 15.2 0.1 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EER29028.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EER29028.1 - 0.021 15.1 0.4 0.031 14.6 0.3 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EER29028.1 - 0.024 12.0 0.3 0.031 11.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_17 PF13207.1 EER29028.1 - 0.026 15.3 0.4 0.085 13.6 0.2 2.0 1 1 1 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EER29028.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 EER29028.1 - 0.031 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EER29028.1 - 0.037 13.4 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EER29028.1 - 0.04 13.8 0.7 0.08 12.9 0.5 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EER29028.1 - 0.087 12.7 0.2 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EER29028.1 - 0.094 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.18 EER29028.1 - 0.097 12.6 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Adeno_IVa2 PF02456.10 EER29028.1 - 0.2 10.3 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_13 PF13166.1 EER29028.1 - 0.2 10.0 0.1 0.28 9.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EER29029.1 - 5e-64 210.0 32.3 3.3e-09 36.2 0.0 13.6 14 0 0 14 14 14 9 WD domain, G-beta repeat Urm1 PF09138.6 EER29030.1 - 2.5e-36 123.6 0.0 2.9e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EER29030.1 - 0.011 16.1 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 0 ThiS family 6PF2K PF01591.13 EER29031.1 - 1.1e-53 181.5 0.0 1.7e-53 180.9 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EER29031.1 - 5.8e-22 78.4 1.4 5.8e-22 78.4 0.9 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EER29031.1 - 0.00025 20.9 0.1 0.00091 19.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EER29031.1 - 0.00045 21.0 3.1 0.012 16.4 2.1 2.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EER29031.1 - 0.0033 16.6 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Porin_3 PF01459.17 EER29032.1 - 1.5e-80 270.4 0.0 1.8e-80 270.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EER29032.1 - 0.0095 15.3 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 EER29033.1 - 2.7e-64 216.8 0.0 3.5e-64 216.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29033.1 - 1.7e-25 89.6 0.0 2.8e-25 88.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER29033.1 - 5.6e-07 28.8 0.0 1.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER29033.1 - 0.00053 19.8 0.1 0.0071 16.1 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER29033.1 - 0.043 13.3 0.0 0.075 12.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase rpo132 PF12415.3 EER29033.1 - 0.073 12.0 0.2 0.75 8.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase MIF4G_like PF09088.6 EER29034.1 - 1.3e-81 272.6 0.1 2.1e-81 271.9 0.1 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EER29034.1 - 4.1e-59 199.8 0.1 1.3e-58 198.2 0.0 1.8 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.14 EER29034.1 - 0.023 14.1 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 MIF4G domain DUF3349 PF11829.3 EER29034.1 - 0.12 12.8 1.1 16 5.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) FA_hydroxylase PF04116.8 EER29035.1 - 4.4e-13 49.6 20.9 2.4e-12 47.2 12.2 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.27 EER29036.1 - 3.7e-75 245.3 12.6 8.7e-12 44.4 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EER29036.1 - 6.2e-25 87.1 8.5 9.1e-25 86.6 5.9 1.2 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EER29036.1 - 1.3e-06 26.9 0.9 0.00017 20.0 0.4 3.0 2 1 0 2 2 2 1 Cytochrome D1 heme domain eIF2A PF08662.6 EER29036.1 - 3e-06 27.0 0.0 0.021 14.5 0.0 3.3 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EER29036.1 - 0.00061 18.0 0.2 0.15 10.1 0.0 3.3 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EER29036.1 - 0.03 13.0 0.0 6.8 5.3 0.1 3.7 2 1 1 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.1 EER29036.1 - 0.049 12.7 0.0 10 5.0 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal GAS PF13851.1 EER29036.1 - 0.066 12.3 1.4 0.089 11.9 1.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding HPS3_N PF14761.1 EER29036.1 - 0.14 11.5 0.0 1.6 8.1 0.0 2.3 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 zf-C2H2 PF00096.21 EER29039.1 - 3.5e-15 55.3 22.4 9.3e-05 22.5 0.4 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER29039.1 - 1.9e-14 53.0 23.6 3.5e-08 33.3 0.8 4.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER29039.1 - 4.6e-11 42.2 20.1 0.0024 18.0 0.2 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 EER29039.1 - 4e-06 26.8 5.8 0.017 15.2 0.1 3.8 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EER29039.1 - 1.3 9.0 6.6 4.6 7.2 0.1 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EER29039.1 - 2.5 8.3 7.7 0.99 9.6 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Mito_carr PF00153.22 EER29041.1 - 3.3e-70 231.8 0.6 3.2e-23 81.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EER29042.1 - 3.1e-35 119.6 0.0 4e-17 61.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29042.1 - 1.2e-18 66.7 0.0 3.1e-08 33.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29042.1 - 6.8e-15 54.6 0.0 2.1e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EER29042.1 - 0.006 16.3 0.2 0.84 9.4 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 Cas_Cas2CT1978 PF09707.5 EER29042.1 - 0.029 14.2 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) OB_RNB PF08206.6 EER29042.1 - 0.16 11.5 0.3 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF2015 PF09435.5 EER29043.1 - 1.9e-46 156.9 0.0 2.2e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Vps55 PF04133.9 EER29043.1 - 0.14 11.9 0.1 0.16 11.7 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 Ribosomal_L28e PF01778.12 EER29044.1 - 7.6e-38 129.5 0.1 9.5e-38 129.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.18 EER29045.1 - 1.2e-44 151.5 0.3 2.5e-44 150.4 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EER29045.1 - 1.5e-37 129.0 0.0 1.9e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EER29045.1 - 7.4e-05 21.5 0.0 0.00011 21.0 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EER29045.1 - 0.022 14.0 0.1 0.086 12.1 0.0 1.9 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase TRAPP PF04051.11 EER29046.1 - 6.2e-46 155.6 0.0 7.3e-46 155.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.1 EER29047.1 - 7.3e-32 110.4 0.1 1.3e-31 109.5 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EER29047.1 - 1.4e-21 75.7 7.2 2.4e-21 74.9 5.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EER29047.1 - 1.9e-05 24.0 3.0 4.1e-05 23.0 2.1 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EER29047.1 - 2.7e-05 23.5 1.3 0.00015 21.1 0.0 2.3 2 0 0 2 2 2 1 SAP domain zf-Sec23_Sec24 PF04810.10 EER29047.1 - 0.12 11.9 3.4 0.29 10.7 1.9 2.0 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 EER29047.1 - 1.4 8.8 4.2 2.6 8.0 2.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2423 PF10338.4 EER29048.1 - 1.4e-18 66.5 4.1 1.4e-18 66.5 2.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.17 EER29049.1 - 3e-19 69.5 0.5 1.9e-17 63.6 0.3 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EER29049.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EER29049.1 - 0.0028 16.8 0.0 0.011 14.9 0.0 1.9 2 0 0 2 2 2 1 Sulfatase DUF229 PF02995.12 EER29049.1 - 0.23 9.8 0.0 0.34 9.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) SPAM PF02090.10 EER29050.1 - 0.65 9.9 3.5 0.73 9.8 0.4 2.0 2 0 0 2 2 2 0 Salmonella surface presentation of antigen gene type M protein NAD_binding_10 PF13460.1 EER29051.1 - 2.5e-15 56.9 0.1 5.4e-15 55.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EER29051.1 - 5.4e-09 35.6 0.2 8e-09 35.0 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EER29051.1 - 3.1e-08 33.3 0.0 5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EER29051.1 - 8.1e-07 29.0 0.0 2.9e-06 27.2 0.1 1.8 2 0 0 2 2 2 1 TrkA-N domain RmlD_sub_bind PF04321.12 EER29051.1 - 2.9e-06 26.4 0.1 1.2e-05 24.4 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.20 EER29051.1 - 5.6e-05 23.1 0.8 0.00014 21.8 0.5 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 EER29051.1 - 6.6e-05 22.0 0.1 9.2e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EER29051.1 - 0.00096 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EER29051.1 - 0.0016 18.2 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 EER29051.1 - 0.0018 17.2 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EER29051.1 - 0.0034 17.0 0.2 0.0056 16.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EER29051.1 - 0.0088 16.3 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.10 EER29051.1 - 0.01 15.4 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein CbiJ PF02571.9 EER29051.1 - 0.012 14.9 0.1 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK NAD_binding_4 PF07993.7 EER29051.1 - 0.027 13.3 0.1 0.05 12.5 0.1 1.5 1 1 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 EER29051.1 - 0.037 13.9 0.1 0.08 12.8 0.0 1.6 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DEDD_Tnp_IS110 PF01548.12 EER29051.1 - 0.057 13.0 0.4 0.14 11.8 0.2 1.6 1 1 0 1 1 1 0 Transposase ApbA PF02558.11 EER29051.1 - 0.14 11.5 0.1 0.31 10.4 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RRM_2 PF04059.7 EER29052.1 - 1.2e-09 38.0 0.3 2.9e-09 36.7 0.1 1.7 2 0 0 2 2 2 1 RNA recognition motif 2 RRM_5 PF13893.1 EER29052.1 - 0.00019 21.1 0.3 0.00059 19.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER29052.1 - 0.00081 18.9 1.0 0.38 10.4 0.1 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.18 EER29053.1 - 1.5e-06 28.1 0.0 3.6e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sec15 PF04091.7 EER29054.1 - 6.8e-117 390.2 0.5 6.8e-117 390.2 0.4 2.3 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Nic96 PF04097.9 EER29054.1 - 0.00046 18.4 3.5 0.00073 17.7 2.4 1.2 1 0 0 1 1 1 1 Nup93/Nic96 COG5 PF10392.4 EER29054.1 - 0.0036 17.2 8.0 0.0084 16.0 3.5 2.8 1 1 1 2 2 2 1 Golgi transport complex subunit 5 DUF2450 PF10475.4 EER29054.1 - 0.013 14.3 5.8 0.029 13.2 4.1 1.6 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EER29054.1 - 0.025 14.2 4.0 0.066 12.9 1.3 2.6 2 0 0 2 2 2 0 Exocyst complex component Sec5 COG2 PF06148.6 EER29054.1 - 0.82 9.5 8.5 0.28 11.0 3.4 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CBFD_NFYB_HMF PF00808.18 EER29055.1 - 1.5e-19 69.7 0.1 7.7e-19 67.5 0.4 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EER29055.1 - 2.4e-12 46.8 0.1 4.2e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EER29055.1 - 0.022 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Pex14_N PF04695.8 EER29055.1 - 0.025 14.6 4.7 0.56 10.2 0.5 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Fcf2 PF08698.6 EER29056.1 - 1.4e-32 111.5 0.1 3.6e-32 110.3 0.1 1.7 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.15 EER29057.1 - 3e-37 127.8 0.7 3.2e-36 124.4 0.5 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.17 EER29058.1 - 3.7e-23 81.1 0.0 7.3e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e TALPID3 PF15324.1 EER29058.1 - 0.11 9.8 0.2 0.14 9.4 0.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target tRNA-synt_1b PF00579.20 EER29059.1 - 1.9e-71 240.5 0.0 2.8e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Oxygenase-NA PF09859.4 EER29061.1 - 0.079 12.2 0.6 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Oxygenase, catalysing oxidative methylation of damaged DNA SWIRM PF04433.12 EER29062.1 - 3e-14 52.8 0.1 6.5e-14 51.8 0.0 1.6 2 0 0 2 2 2 1 SWIRM domain DUF4360 PF14273.1 EER29063.1 - 2.7e-58 196.6 0.0 3.2e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CDC50 PF03381.10 EER29064.1 - 1.7e-102 342.3 0.0 2.1e-102 342.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 EER29064.1 - 0.14 12.3 1.0 13 6.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) SPT16 PF08644.6 EER29065.1 - 5.1e-59 198.4 0.0 1.7e-58 196.7 0.0 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EER29065.1 - 6e-53 178.7 0.0 1.6e-52 177.3 0.0 1.8 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EER29065.1 - 1.6e-22 80.1 0.0 2.8e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EER29065.1 - 8.4e-20 70.5 0.0 1.9e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Mito_carr PF00153.22 EER29066.1 - 4.9e-19 67.8 2.0 9.7e-13 47.6 0.0 3.7 3 1 0 3 3 3 2 Mitochondrial carrier protein Sugar_tr PF00083.19 EER29067.1 - 4.4e-100 335.3 16.1 5.1e-100 335.1 11.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER29067.1 - 2.1e-31 108.9 49.3 7.4e-29 100.5 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EER29067.1 - 0.0013 18.4 1.0 0.0074 16.0 0.1 2.4 2 0 0 2 2 2 1 MFS_1 like family PMT PF02366.13 EER29068.1 - 3.6e-87 291.7 19.7 3.6e-87 291.7 13.6 2.6 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EER29068.1 - 4.2e-39 134.0 0.5 5.7e-39 133.6 0.3 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 EER29069.1 - 4.8e-46 156.0 0.0 4.2e-35 120.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EER29069.1 - 1.3e-15 57.9 0.0 2.7e-10 40.7 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EER29069.1 - 1.7e-08 33.9 0.0 1.6e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EER29069.1 - 3.6e-07 29.7 0.0 1.2e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EER29069.1 - 1.2e-05 24.5 0.0 8e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EER29069.1 - 0.0048 16.8 0.0 0.041 13.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EER29069.1 - 0.057 13.5 0.0 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EER29069.1 - 0.078 12.1 0.0 0.19 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EER29069.1 - 0.086 12.2 0.0 10 5.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF605 PF04652.11 EER29069.1 - 0.66 9.3 12.6 0.82 8.9 8.8 1.1 1 0 0 1 1 1 0 Vta1 like Choline_transpo PF04515.7 EER29070.1 - 9.3e-09 34.4 14.4 9.3e-09 34.4 10.0 3.0 3 0 0 3 3 3 1 Plasma-membrane choline transporter MFS_1 PF07690.11 EER29072.1 - 4.1e-14 52.0 1.0 4.7e-13 48.5 1.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER29072.1 - 0.0048 15.5 0.8 0.0088 14.6 0.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2193 PF09959.4 EER29072.1 - 0.011 14.0 0.0 0.014 13.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) Zn_clus PF00172.13 EER29073.1 - 2.1e-06 27.5 7.8 3.7e-06 26.7 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EER29074.1 - 2.2e-50 171.0 0.0 2.7e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EER29075.1 - 2.1e-119 399.0 0.0 2.6e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-CCHC PF00098.18 EER29077.1 - 1e-43 145.2 52.4 7e-09 35.1 1.0 6.8 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_4 PF14392.1 EER29077.1 - 9.7e-12 44.3 36.1 0.015 14.9 0.4 6.2 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_3 PF13917.1 EER29077.1 - 0.00049 19.7 45.4 0.026 14.2 1.0 6.2 1 1 5 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.1 EER29077.1 - 0.0033 17.0 36.9 0.69 9.6 0.3 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 EER29077.1 - 0.028 13.9 0.1 0.028 13.9 0.1 6.4 5 1 1 6 6 6 0 Zinc knuckle F-box PF00646.28 EER29078.1 - 1.8e-09 37.0 1.1 3.2e-09 36.2 0.8 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EER29078.1 - 2e-08 33.8 1.0 3.9e-08 32.9 0.7 1.5 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EER29078.1 - 0.002 17.9 0.9 3.1 7.8 0.2 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat CPSF_A PF03178.10 EER29078.1 - 0.006 15.7 0.0 0.015 14.4 0.0 1.6 2 0 0 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.1 EER29078.1 - 0.032 13.7 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 PQQ-like domain CNH PF00780.17 EER29078.1 - 0.068 12.5 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 CNH domain SAE2 PF08573.5 EER29079.1 - 1.1e-23 83.7 1.9 2e-23 82.8 0.0 2.4 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus CASP_C PF08172.7 EER29079.1 - 0.0021 17.1 3.4 0.0042 16.1 2.4 1.5 1 0 0 1 1 1 1 CASP C terminal CCDC155 PF14662.1 EER29079.1 - 0.016 14.8 5.4 0.03 13.9 3.8 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 EER29079.1 - 0.048 14.0 1.5 0.13 12.6 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 EER29079.1 - 0.063 11.1 0.9 0.087 10.6 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 EER29079.1 - 0.098 12.3 5.7 0.036 13.7 1.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Sipho_Gp157 PF05565.6 EER29079.1 - 0.15 11.6 4.1 0.044 13.3 0.7 1.6 2 0 0 2 2 2 0 Siphovirus Gp157 APG6 PF04111.7 EER29079.1 - 0.33 9.9 3.5 0.52 9.3 2.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 EER29079.1 - 0.37 10.6 8.9 0.05 13.4 1.6 2.5 1 1 1 2 2 2 0 Basic region leucine zipper Shugoshin_N PF07558.6 EER29079.1 - 0.6 9.8 4.0 0.4 10.4 0.8 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region IncA PF04156.9 EER29079.1 - 5 6.6 9.6 13 5.3 6.7 1.7 1 1 0 1 1 1 0 IncA protein Pex16 PF08610.5 EER29080.1 - 9.1e-113 376.6 0.0 1.1e-112 376.4 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 EER29081.1 - 1.5e-45 155.2 0.0 3.1e-45 154.2 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII Mif2_N PF15624.1 EER29082.1 - 2e-38 132.0 1.9 2e-38 132.0 1.3 4.0 4 1 0 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.3 EER29082.1 - 6.3e-34 115.8 0.9 1.2e-33 114.9 0.7 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 EER29082.1 - 1.6e-07 30.6 0.0 4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Cupin domain CAP_GLY PF01302.20 EER29083.1 - 2.3e-28 97.6 0.0 3.5e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EER29083.1 - 1.4e-15 57.3 0.0 2.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EER29083.1 - 0.0032 16.8 0.0 0.0072 15.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin family Methyltransf_11 PF08241.7 EER29084.1 - 5.3e-11 42.8 0.0 1.1e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER29084.1 - 1.6e-06 27.9 0.0 2.6e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER29084.1 - 1.3e-05 25.6 0.0 2.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER29084.1 - 1.6e-05 25.1 0.0 3.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER29084.1 - 0.00019 22.0 0.0 0.00035 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER29084.1 - 0.00043 19.9 0.0 0.00079 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Myb_DNA-binding PF00249.26 EER29085.1 - 3e-10 39.9 3.1 6.6e-08 32.4 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER29085.1 - 2.7e-07 30.5 3.6 0.00033 20.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain UCH PF00443.24 EER29086.1 - 2.6e-19 69.3 0.1 4e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EER29086.1 - 5.2e-13 49.0 0.0 8.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SWIM PF04434.12 EER29086.1 - 1.8 8.1 4.8 8.4 5.9 0.1 2.7 2 0 0 2 2 2 0 SWIM zinc finger MitMem_reg PF13012.1 EER29087.1 - 2.8e-40 136.9 0.8 2.8e-40 136.9 0.5 1.9 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EER29087.1 - 6.5e-28 96.7 0.1 1.9e-27 95.2 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ADK PF00406.17 EER29088.1 - 3e-61 205.7 0.1 3.7e-61 205.4 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EER29088.1 - 1.1e-14 53.8 0.0 3e-14 52.4 0.0 1.8 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EER29088.1 - 2.1e-05 24.4 0.0 3.6e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EER29088.1 - 0.00047 20.9 0.0 0.00089 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EER29088.1 - 0.0022 17.1 0.0 0.004 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EER29088.1 - 0.0038 17.5 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EER29088.1 - 0.023 13.8 0.1 0.034 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 EER29088.1 - 0.036 13.4 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF826 PF05696.6 EER29088.1 - 0.075 13.1 0.5 0.53 10.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Thymidylate_kin PF02223.12 EER29088.1 - 0.086 12.2 0.2 0.33 10.2 0.0 1.8 1 1 1 2 2 2 0 Thymidylate kinase HNH_2 PF13391.1 EER29090.1 - 1.9e-06 27.5 0.0 2.6e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 HNH endonuclease GFO_IDH_MocA PF01408.17 EER29091.1 - 1.3e-19 70.9 0.1 2.3e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EER29091.1 - 0.0085 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CFIA_Pcf11 PF11526.3 EER29092.1 - 0.00026 21.0 0.8 0.00098 19.2 0.6 2.0 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.8 EER29092.1 - 0.0007 19.7 0.0 0.0024 18.0 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.14 EER29092.1 - 0.0064 16.1 0.0 0.021 14.4 0.0 1.8 2 0 0 2 2 2 1 VHS domain RRN7 PF11781.3 EER29092.1 - 0.25 10.8 2.8 0.71 9.4 0.3 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-ISL3 PF14690.1 EER29092.1 - 0.28 11.2 2.7 0.29 11.2 0.2 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC_2 PF13913.1 EER29092.1 - 0.37 10.5 5.5 4.7 6.9 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 EER29092.1 - 3 8.3 4.3 30 5.2 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Inhibitor_I9 PF05922.11 EER29093.1 - 0.0072 16.8 0.1 0.011 16.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 ERG4_ERG24 PF01222.12 EER29094.1 - 6.7e-159 529.0 8.3 7.9e-159 528.7 5.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EER29094.1 - 0.00055 19.3 0.2 0.00055 19.3 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Methyltransf_23 PF13489.1 EER29095.1 - 4e-19 68.9 0.0 8.1e-19 67.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER29095.1 - 8.5e-09 35.9 0.0 8.2e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER29095.1 - 2e-08 34.5 0.0 3.9e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER29095.1 - 1.8e-06 27.5 0.0 1.1e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER29095.1 - 4.6e-06 27.0 0.0 3.2e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER29095.1 - 0.0021 18.0 0.0 0.0084 16.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EER29095.1 - 0.0036 16.5 0.0 0.0051 16.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_16 PF10294.4 EER29095.1 - 0.0053 16.2 0.0 0.0083 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EER29095.1 - 0.014 15.7 0.0 0.034 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EER29095.1 - 0.03 14.2 0.1 0.078 12.9 0.0 1.7 1 1 1 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EER29095.1 - 0.049 12.7 0.0 0.33 10.0 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EER29095.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EER29095.1 - 0.15 11.4 0.0 0.42 9.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain HOOK PF05622.7 EER29096.1 - 7.1e-19 67.1 71.4 6.1e-16 57.4 49.5 3.7 1 1 0 1 1 1 1 HOOK protein MAD PF05557.8 EER29096.1 - 2.6 6.0 81.3 0.002 16.3 30.6 3.0 2 1 0 2 2 2 0 Mitotic checkpoint protein Occludin_ELL PF07303.8 EER29096.1 - 9.1 7.0 52.5 0.9 10.3 0.5 7.2 4 4 3 8 8 8 0 Occludin homology domain Coprogen_oxidas PF01218.13 EER29097.1 - 1.4e-122 407.9 0.0 3.7e-122 406.5 0.0 1.6 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 EER29098.1 - 5.5e-51 170.8 0.2 6.5e-51 170.6 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EER29098.1 - 1.2e-06 28.6 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pkinase PF00069.20 EER29099.1 - 0.066 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Mito_carr PF00153.22 EER29101.1 - 2.6e-27 94.3 1.5 2.8e-15 55.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Chs3p PF12271.3 EER29104.1 - 0.07 12.0 8.1 0.094 11.6 5.6 1.1 1 0 0 1 1 1 0 Chitin synthase III catalytic subunit Tad PF13400.1 EER29104.1 - 2.8 8.0 5.8 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like adh_short PF00106.20 EER29105.1 - 1.8e-15 57.2 0.3 1.3e-14 54.4 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER29105.1 - 2.6e-07 30.6 0.0 9.3e-07 28.8 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER29105.1 - 2.1e-05 24.2 0.1 3.6e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EER29105.1 - 0.00068 19.1 0.0 0.0048 16.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EER29105.1 - 0.0044 17.0 0.1 0.018 15.0 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding APH PF01636.18 EER29107.1 - 1.1e-05 25.2 0.0 2.5e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Mus7 PF09462.5 EER29108.1 - 3.3e-184 614.1 0.1 5.5e-184 613.4 0.0 1.4 1 0 0 1 1 1 1 Mus7/MMS22 family PAPA-1 PF04795.7 EER29109.1 - 3.5e-29 101.3 5.3 3.5e-29 101.3 3.7 3.5 3 1 0 3 3 3 1 PAPA-1-like conserved region Pex14_N PF04695.8 EER29110.1 - 2.3e-29 102.1 4.1 2.3e-29 102.1 2.8 2.2 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 EER29110.1 - 0.008 16.0 1.0 0.062 13.1 0.2 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus WD40 PF00400.27 EER29111.1 - 4.1e-16 58.1 10.3 5.1e-05 22.9 0.1 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Sec16_C PF12931.2 EER29111.1 - 0.022 14.5 0.5 0.079 12.6 0.4 1.8 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 Tuberin PF03542.11 EER29111.1 - 0.033 13.2 0.0 0.05 12.6 0.0 1.2 1 0 0 1 1 1 0 Tuberin TPR_19 PF14559.1 EER29111.1 - 0.071 13.4 1.5 0.38 11.1 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RRM_1 PF00076.17 EER29112.1 - 3.8e-15 55.2 0.0 1.5e-14 53.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29112.1 - 5e-10 39.2 0.0 9e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29112.1 - 3e-09 36.6 0.0 2e-08 33.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 EER29114.1 - 1.5e-19 69.7 6.0 1.9e-19 69.4 4.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EER29114.1 - 0.003 16.9 0.5 0.0051 16.1 0.3 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain CHCH PF06747.8 EER29114.1 - 0.053 13.4 0.6 0.13 12.1 0.4 1.7 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 EER29114.1 - 1.1 9.1 4.5 4 7.3 0.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Mito_carr PF00153.22 EER29115.1 - 1.6e-48 162.3 0.7 2e-19 69.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein tRNA-synt_2d PF01409.15 EER29116.1 - 2.1e-45 154.8 0.1 1.7e-23 83.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EER29116.1 - 9.8e-28 96.1 0.0 3.3e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EER29116.1 - 0.057 12.1 0.3 0.37 9.5 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) GrpE PF01025.14 EER29117.1 - 2.3e-44 150.8 2.8 3.2e-44 150.3 1.9 1.3 1 0 0 1 1 1 1 GrpE Phage_lysis PF03245.8 EER29117.1 - 0.065 13.2 1.6 0.099 12.6 1.1 1.4 1 0 0 1 1 1 0 Bacteriophage Rz lysis protein POX PF07526.6 EER29117.1 - 0.093 12.9 1.7 0.14 12.3 1.1 1.3 1 0 0 1 1 1 0 Associated with HOX Uds1 PF15456.1 EER29118.1 - 2.2e-34 118.1 9.6 2.2e-34 118.1 6.6 1.9 2 0 0 2 2 2 1 Up-regulated During Septation Stathmin PF00836.14 EER29118.1 - 0.25 10.9 3.7 0.65 9.6 2.6 1.7 1 0 0 1 1 1 0 Stathmin family HALZ PF02183.13 EER29118.1 - 0.49 10.1 3.2 0.6 9.8 0.2 2.6 2 1 0 2 2 2 0 Homeobox associated leucine zipper Wbp11 PF09429.5 EER29118.1 - 3.1 7.8 7.0 0.48 10.4 0.4 2.7 3 0 0 3 3 3 0 WW domain binding protein 11 Lactonase PF10282.4 EER29119.1 - 3.5e-91 305.8 0.0 4.1e-91 305.6 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller GSDH PF07995.6 EER29119.1 - 0.0059 15.7 0.0 0.12 11.3 0.0 2.5 3 1 0 3 3 3 1 Glucose / Sorbosone dehydrogenase WD40 PF00400.27 EER29119.1 - 0.082 12.8 0.0 4.4 7.3 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1513 PF07433.6 EER29119.1 - 0.14 11.0 0.6 1.8 7.3 0.0 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1513) Calcipressin PF04847.7 EER29120.1 - 2.6e-31 108.6 1.0 3.9e-31 108.0 0.7 1.3 1 0 0 1 1 1 1 Calcipressin Transp_cyt_pur PF02133.10 EER29121.1 - 7.9e-38 130.1 32.7 9.2e-36 123.3 22.7 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ATE_C PF04377.10 EER29122.1 - 6.9e-26 90.7 5.7 4e-25 88.3 4.0 2.1 1 1 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EER29122.1 - 2e-21 75.5 5.5 2e-21 75.5 3.8 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Vma12 PF11712.3 EER29122.1 - 0.054 13.1 0.6 0.089 12.5 0.4 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RNA_pol_A_bac PF01000.21 EER29123.1 - 9.5e-32 109.4 0.0 1.5e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EER29123.1 - 1.8e-13 49.4 0.0 3.1e-13 48.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EER29123.1 - 0.02 14.3 0.1 0.046 13.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF22 RVT_2 PF07727.9 EER29124.1 - 6.1e-69 231.7 0.0 1.9e-68 230.1 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EER29124.1 - 3.5e-19 69.0 0.0 1.9e-18 66.7 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 EER29124.1 - 3.1e-06 26.7 0.1 7.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 EER29124.1 - 1.2e-05 25.0 2.3 2.3e-05 24.0 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle Phage_Gp23 PF10669.4 EER29124.1 - 1.4 9.0 11.1 0.1 12.7 2.6 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) NUDIX PF00293.23 EER29125.1 - 6.7e-20 71.1 0.4 8e-20 70.8 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain DUF2816 PF10992.3 EER29126.1 - 0.031 13.8 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2816) Lactonase PF10282.4 EER29126.1 - 0.1 11.6 0.0 7 5.6 0.0 2.4 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Baculo_PEP_C PF04513.7 EER29127.1 - 0.14 12.0 0.4 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3439 PF11921.3 EER29127.1 - 1.2 8.9 4.0 2.2 8.0 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Cytochrom_C PF00034.16 EER29128.1 - 1.6e-11 44.8 0.1 2.4e-11 44.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EER29128.1 - 5.2e-09 36.1 3.9 5.4e-08 32.8 2.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EER29128.1 - 0.012 15.0 1.4 0.022 14.2 0.9 1.7 1 1 0 1 1 1 0 Cytochrome c-550 domain CCP_MauG PF03150.9 EER29128.1 - 0.021 15.1 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase RNase_PH PF01138.16 EER29130.1 - 4.5e-13 49.6 0.1 1.3e-11 44.9 0.1 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Pkinase PF00069.20 EER29131.1 - 2.9e-61 206.8 0.0 4.2e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29131.1 - 9.4e-34 116.6 0.0 1.4e-31 109.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EER29131.1 - 0.024 13.4 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Stn1 PF10451.4 EER29134.1 - 8.5e-12 44.4 0.1 4.9e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EER29134.1 - 6.4e-05 22.7 0.0 0.34 10.7 0.0 2.6 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain U79_P34 PF03064.11 EER29134.1 - 1.2 8.6 10.7 1.8 8.0 7.4 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 EER29134.1 - 1.6 8.5 6.4 2.4 7.9 4.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3513 PF12026.3 EER29134.1 - 2.7 7.4 7.3 4.2 6.8 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) tRNA-synt_1b PF00579.20 EER29135.1 - 1.4e-23 83.4 0.0 3e-23 82.3 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) MFS_1 PF07690.11 EER29136.1 - 7.9e-31 107.0 38.1 7.9e-31 107.0 26.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER29136.1 - 2.2e-06 26.2 16.3 6.9e-06 24.5 11.3 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER29136.1 - 7.7e-06 24.7 10.3 7.7e-06 24.7 7.1 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter SET PF00856.23 EER29137.1 - 5e-12 46.4 0.2 1.1e-10 42.0 0.1 2.4 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.17 EER29138.1 - 2e-09 37.0 0.0 6.1e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EER29138.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 1 0 1 1 1 0 APOBEC-like N-terminal domain DnaJ PF00226.26 EER29139.1 - 2.7e-23 81.4 2.6 2.7e-23 81.4 1.8 2.3 3 0 0 3 3 3 1 DnaJ domain Usp PF00582.21 EER29140.1 - 1.6e-17 63.9 0.7 8.6e-10 38.9 0.2 2.6 2 0 0 2 2 2 2 Universal stress protein family Peptidase_S10 PF00450.17 EER29141.1 - 3.9e-77 260.1 0.0 7.8e-77 259.1 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Cu_bind_like PF02298.12 EER29142.1 - 0.12 12.1 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 Plastocyanin-like domain ATP-synt_ab PF00006.20 EER29143.1 - 8.6e-62 208.4 0.0 1.2e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EER29143.1 - 3.2e-16 59.7 0.0 5.7e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EER29143.1 - 1.8e-10 40.8 0.4 3.7e-10 39.8 0.3 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EER29143.1 - 0.0011 18.7 0.3 0.0024 17.7 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Trp_syntA PF00290.15 EER29144.1 - 8.3e-91 303.0 0.3 1.4e-90 302.3 0.0 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 EER29144.1 - 8.6e-43 146.7 2.0 1.6e-42 145.8 1.4 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 EER29146.1 - 3.5e-26 91.2 0.2 5.4e-26 90.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER29146.1 - 2.5e-08 34.8 0.1 8.2e-08 33.1 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER29146.1 - 2.8e-05 23.8 0.0 5.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EER29146.1 - 0.021 14.8 0.6 0.05 13.6 0.2 1.9 2 1 0 2 2 2 0 NADH(P)-binding AlaDh_PNT_C PF01262.16 EER29146.1 - 0.028 13.9 0.4 0.054 13.0 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GAD PF02938.9 EER29146.1 - 0.056 13.6 0.1 0.28 11.3 0.0 2.1 2 0 0 2 2 2 0 GAD domain GYF PF02213.11 EER29147.1 - 2.2e-15 55.9 0.1 5.4e-15 54.7 0.1 1.7 1 0 0 1 1 1 1 GYF domain Aminotran_5 PF00266.14 EER29148.1 - 5e-19 68.2 0.0 7.5e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EER29148.1 - 0.0069 14.7 0.0 0.01 14.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme zf-RING_2 PF13639.1 EER29149.1 - 1.3e-14 53.6 8.3 2.1e-14 53.0 5.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EER29149.1 - 8.5e-08 31.7 3.9 1.2e-07 31.2 2.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EER29149.1 - 1.3e-06 28.4 5.3 2.4e-06 27.5 3.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EER29149.1 - 2.2e-06 27.5 7.7 3.5e-06 26.9 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER29149.1 - 5.8e-06 25.8 7.8 9.5e-06 25.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER29149.1 - 1.4e-05 24.7 5.7 2e-05 24.1 3.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EER29149.1 - 0.011 15.5 2.4 0.023 14.5 1.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EER29149.1 - 0.064 13.0 0.5 0.12 12.2 0.4 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_6 PF14835.1 EER29149.1 - 0.36 10.6 2.0 0.66 9.8 1.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PHD PF00628.24 EER29149.1 - 0.46 10.2 7.0 0.8 9.4 4.9 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EER29149.1 - 1 9.0 4.2 1.7 8.3 2.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EER29149.1 - 1.3 9.0 7.5 5.1 7.1 5.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EER29149.1 - 1.8 8.4 6.0 4.1 7.3 4.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EER29149.1 - 3.8 7.6 9.7 7.3 6.7 6.7 1.4 1 0 0 1 1 1 0 RING-variant domain Fis1_TPR_C PF14853.1 EER29150.1 - 1.4e-26 92.1 1.4 2.2e-26 91.4 1.0 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EER29150.1 - 1.1e-17 63.0 0.0 1.9e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EER29150.1 - 0.0024 17.6 1.7 0.0058 16.4 1.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EER29150.1 - 0.0034 18.0 0.2 0.0075 16.9 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Spc24 PF08286.6 EER29151.1 - 8.6e-40 135.1 2.1 7.7e-39 132.0 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 APG6 PF04111.7 EER29151.1 - 0.024 13.7 2.9 0.029 13.4 2.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 WXG100 PF06013.7 EER29151.1 - 0.1 12.5 0.2 0.1 12.5 0.1 2.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG TBPIP PF07106.8 EER29151.1 - 0.19 11.2 3.9 0.57 9.7 0.7 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 EER29151.1 - 0.22 11.3 4.5 0.37 10.5 0.5 2.2 2 0 0 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 EER29151.1 - 0.45 9.9 6.0 0.7 9.3 0.2 2.3 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Syntaxin PF00804.20 EER29151.1 - 0.7 10.0 8.0 2.3 8.4 2.4 2.3 1 1 1 2 2 2 0 Syntaxin FUSC PF04632.7 EER29151.1 - 2.9 6.2 5.2 3.4 5.9 3.6 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF663 PF04950.7 EER29152.1 - 6e-91 304.5 0.0 1.3e-90 303.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EER29152.1 - 1.7e-26 91.5 0.0 3.5e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EER29152.1 - 4.6e-07 29.4 0.0 4.3e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EER29152.1 - 4.6e-05 23.5 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EER29152.1 - 6.9e-05 22.5 0.2 0.00016 21.3 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EER29152.1 - 7.8e-05 22.7 0.1 0.00031 20.8 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain AAA_17 PF13207.1 EER29152.1 - 0.00028 21.7 0.0 0.00028 21.7 0.0 4.0 2 1 0 2 2 1 1 AAA domain AAA PF00004.24 EER29152.1 - 0.00034 20.8 0.0 0.00095 19.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EER29152.1 - 0.00068 19.5 0.1 0.0021 18.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EER29152.1 - 0.0011 18.8 1.0 0.0022 17.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EER29152.1 - 0.0015 18.0 0.1 0.006 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EER29152.1 - 0.0022 18.4 0.0 0.0064 16.9 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 EER29152.1 - 0.0025 18.1 0.4 0.017 15.4 0.0 2.8 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.22 EER29152.1 - 0.0025 18.0 0.7 0.0067 16.7 0.0 2.0 2 0 0 2 2 1 1 ABC transporter NACHT PF05729.7 EER29152.1 - 0.0029 17.3 0.0 0.0059 16.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 EER29152.1 - 0.0034 17.0 0.2 0.0073 16.0 0.1 1.5 1 0 0 1 1 1 1 NTPase Zeta_toxin PF06414.7 EER29152.1 - 0.0038 16.3 0.0 0.015 14.3 0.0 2.0 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 EER29152.1 - 0.0052 15.6 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_10 PF12846.2 EER29152.1 - 0.0075 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain AAA_24 PF13479.1 EER29152.1 - 0.0092 15.5 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EER29152.1 - 0.012 15.0 0.1 0.025 14.0 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EER29152.1 - 0.012 14.3 0.0 0.027 13.2 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_14 PF13173.1 EER29152.1 - 0.017 15.0 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EER29152.1 - 0.02 14.3 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 EER29152.1 - 0.026 13.5 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_19 PF13245.1 EER29152.1 - 0.028 14.1 0.1 0.028 14.1 0.1 2.1 2 0 0 2 2 1 0 Part of AAA domain RNA_helicase PF00910.17 EER29152.1 - 0.028 14.6 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 EER29152.1 - 0.036 13.2 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SRP54 PF00448.17 EER29152.1 - 0.047 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 EER29152.1 - 0.048 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ATP_bind_1 PF03029.12 EER29152.1 - 0.069 12.6 0.1 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 EER29152.1 - 0.094 12.4 0.2 0.33 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.13 EER29152.1 - 0.11 11.5 0.1 0.51 9.3 0.0 2.0 2 0 0 2 2 2 0 Septin FeoB_N PF02421.13 EER29152.1 - 0.25 10.6 0.0 0.46 9.7 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_11 PF13086.1 EER29152.1 - 0.28 10.7 2.8 0.63 9.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.20 EER29153.1 - 4e-09 35.9 0.0 7.2e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29153.1 - 0.0079 15.3 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER29153.1 - 0.061 13.0 0.2 0.4 10.3 0.1 2.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EER29153.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF1989 PF09347.5 EER29154.1 - 3e-56 189.4 0.0 3.8e-56 189.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) DUF346 PF03984.8 EER29154.1 - 0.064 12.7 0.2 0.17 11.3 0.2 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) PBP_like_2 PF12849.2 EER29155.1 - 2.6e-09 36.9 0.2 3.6e-09 36.5 0.2 1.2 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_8 PF13416.1 EER29155.1 - 0.00067 19.4 0.7 0.0014 18.4 0.5 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.1 EER29155.1 - 0.088 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein YaeQ PF07152.7 EER29156.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 YaeQ protein Inhibitor_I9 PF05922.11 EER29157.1 - 0.0051 17.3 0.1 0.0062 17.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 Tom5 PF10642.4 EER29157.1 - 0.051 13.2 0.1 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase DUF3425 PF11905.3 EER29159.1 - 1.1e-23 83.6 0.1 1.8e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EER29159.1 - 0.015 15.2 10.0 0.015 15.2 6.9 1.6 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EER29159.1 - 0.37 10.6 9.8 0.71 9.7 6.8 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Abhydrolase_6 PF12697.2 EER29160.1 - 1.8e-23 83.6 0.0 2.2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER29160.1 - 1.6e-07 31.1 0.0 2.8e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER29160.1 - 4.1e-06 26.5 0.0 2.5e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EER29160.1 - 0.0018 18.0 0.0 0.0048 16.7 0.0 1.8 1 1 0 1 1 1 1 Putative lysophospholipase CRIC_ras_sig PF10534.4 EER29160.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras BCDHK_Adom3 PF10436.4 EER29161.1 - 5.6e-43 146.2 0.0 7.9e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EER29161.1 - 7.6e-15 54.6 0.0 2.6e-14 52.8 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Carboxyl_trans PF01039.17 EER29162.1 - 3.1e-74 250.1 0.0 4.3e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EER29163.1 - 6.9e-56 188.8 0.1 1.1e-55 188.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EER29163.1 - 2.3e-30 104.6 0.0 4.8e-30 103.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EER29163.1 - 2.6e-18 66.4 0.1 5e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EER29163.1 - 6.3e-11 41.5 0.0 2.2e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EER29163.1 - 7.7e-11 41.4 3.6 1.7e-10 40.3 0.2 2.9 3 0 0 3 3 3 1 Biotin-requiring enzyme CPSase_L_chain PF00289.17 EER29163.1 - 2.4e-10 40.5 0.1 1e-09 38.4 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Dala_Dala_lig_C PF07478.8 EER29163.1 - 2.5e-10 40.1 0.1 5.3e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EER29163.1 - 2.6e-07 30.1 0.1 4.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EER29163.1 - 3.8e-06 26.8 0.0 7.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EER29163.1 - 0.00047 19.7 0.2 0.024 14.2 0.0 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.1 EER29163.1 - 0.00067 19.3 0.3 0.038 13.7 0.0 3.2 2 1 1 3 3 3 1 RnfC Barrel sandwich hybrid domain RimK PF08443.6 EER29163.1 - 0.0057 16.1 0.0 0.022 14.2 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain DUF2118 PF09891.4 EER29163.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) HlyD_2 PF12700.2 EER29163.1 - 0.065 12.3 0.0 0.46 9.5 0.0 1.9 1 1 1 2 2 2 0 HlyD family secretion protein ATPgrasp_ST PF14397.1 EER29163.1 - 0.12 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GCN5L1 PF06320.8 EER29165.1 - 9.3e-12 44.8 0.2 1.1e-11 44.5 0.1 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF3552 PF12072.3 EER29165.1 - 0.0099 15.1 4.0 0.011 14.9 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) DUF2884 PF11101.3 EER29165.1 - 0.039 13.3 0.4 0.056 12.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Sec34 PF04136.10 EER29165.1 - 0.054 13.2 0.3 0.065 12.9 0.2 1.1 1 0 0 1 1 1 0 Sec34-like family TMF_DNA_bd PF12329.3 EER29165.1 - 0.08 12.7 7.6 0.11 12.3 5.3 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3585 PF12130.3 EER29165.1 - 0.14 12.0 5.3 0.41 10.4 3.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3585) DNA_mis_repair PF01119.14 EER29166.1 - 9.7e-21 73.4 0.0 2.9e-19 68.6 0.0 2.8 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 EER29166.1 - 2.8e-17 62.6 0.4 4.4e-16 58.7 0.3 2.5 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EER29166.1 - 2.3e-14 53.2 0.0 6.4e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EER29166.1 - 7.1e-12 45.0 0.0 2e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serinc PF03348.10 EER29167.1 - 4.1e-177 589.2 5.6 4.7e-177 589.0 3.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.11 EER29168.1 - 1e-08 34.2 36.8 1.5e-05 23.8 11.3 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EER29168.1 - 2.1e-07 30.4 1.5 2.1e-07 30.4 1.1 2.1 2 0 0 2 2 2 1 Nodulin-like GATA PF00320.22 EER29169.1 - 1.6e-15 56.1 2.4 3.3e-15 55.1 1.7 1.6 1 0 0 1 1 1 1 GATA zinc finger Pox_A_type_inc PF04508.7 EER29169.1 - 0.0024 17.4 3.8 0.023 14.4 1.4 2.9 2 0 0 2 2 2 1 Viral A-type inclusion protein repeat Spc7 PF08317.6 EER29169.1 - 0.043 12.4 6.0 0.063 11.9 4.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF745 PF05335.8 EER29169.1 - 0.048 13.1 2.1 0.082 12.4 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) HR1 PF02185.11 EER29169.1 - 0.12 12.1 6.6 0.25 11.1 4.6 1.5 1 0 0 1 1 1 0 Hr1 repeat Phage_GP20 PF06810.6 EER29169.1 - 0.13 11.6 3.8 0.21 10.9 2.6 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIVA PF05103.8 EER29169.1 - 0.14 12.1 8.7 0.45 10.5 6.0 1.7 1 1 0 1 1 1 0 DivIVA protein GAS PF13851.1 EER29169.1 - 0.15 11.2 7.0 0.21 10.7 4.8 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TF_Zn_Ribbon PF08271.7 EER29169.1 - 0.34 10.2 1.2 0.76 9.1 0.1 2.1 2 0 0 2 2 2 0 TFIIB zinc-binding Fmp27_WPPW PF10359.4 EER29169.1 - 0.35 9.2 5.1 0.53 8.6 3.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DZR PF12773.2 EER29169.1 - 0.37 10.6 3.8 1 9.2 0.9 2.7 2 1 1 3 3 3 0 Double zinc ribbon APG6 PF04111.7 EER29169.1 - 0.45 9.4 6.8 0.65 8.9 4.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 WD40_alt PF14077.1 EER29169.1 - 1.2 8.8 6.0 12 5.6 1.1 2.8 2 1 0 2 2 2 0 Alternative WD40 repeat motif ADIP PF11559.3 EER29169.1 - 3.5 7.5 12.3 2.5 7.9 0.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DivIC PF04977.10 EER29169.1 - 3.8 7.0 6.8 2 7.9 2.0 2.1 2 0 0 2 2 2 0 Septum formation initiator zf-ribbon_3 PF13248.1 EER29169.1 - 4.6 6.5 9.2 35 3.7 0.1 3.1 2 1 0 2 2 2 0 zinc-ribbon domain IncA PF04156.9 EER29169.1 - 8.3 5.9 13.8 0.64 9.5 6.1 1.7 2 0 0 2 2 2 0 IncA protein zinc_ribbon_2 PF13240.1 EER29169.1 - 8.9 5.9 8.5 13 5.4 0.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain PI3_PI4_kinase PF00454.22 EER29170.1 - 1.8e-38 132.3 0.0 3.4e-38 131.4 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 EER29171.1 - 2.2e-61 207.2 0.1 3.8e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER29171.1 - 3.7e-08 33.1 0.0 9.3e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EER29171.1 - 3.1e-06 26.7 0.0 1e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HIRAN PF08797.6 EER29171.1 - 0.0019 18.1 0.0 0.005 16.7 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain DUF3873 PF12989.2 EER29171.1 - 0.016 15.3 0.0 1.5 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3873) 7TMR-HDED PF07697.6 EER29171.1 - 0.039 13.7 1.7 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 7TM-HD extracellular Osmo_CC PF08946.5 EER29171.1 - 0.057 13.4 0.9 0.13 12.2 0.6 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DEAD_2 PF06733.10 EER29171.1 - 0.08 12.3 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 Med21 PF11221.3 EER29172.1 - 1e-56 190.9 9.8 3.8e-56 189.0 6.8 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EER29172.1 - 0.022 14.4 4.0 0.068 12.9 2.8 1.9 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 IncA PF04156.9 EER29172.1 - 0.15 11.6 3.3 0.2 11.2 1.3 1.8 2 0 0 2 2 2 0 IncA protein DUF3431 PF11913.3 EER29173.1 - 8e-89 296.9 0.0 9.6e-89 296.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF2034 PF10356.4 EER29174.1 - 3.1e-36 124.2 0.0 1.5e-20 73.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EER29174.1 - 1.9e-07 30.8 0.0 5.5e-07 29.3 0.0 1.7 1 1 1 2 2 2 1 Restriction endonuclease RRM_6 PF14259.1 EER29175.1 - 1.2e-10 41.2 0.8 1e-09 38.2 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29175.1 - 1.6e-07 31.0 0.0 3.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER29175.1 - 4.2e-07 29.4 0.1 5.7e-06 25.8 0.1 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER29175.1 - 9.6e-05 22.0 0.0 0.0037 16.9 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif PWI PF01480.12 EER29175.1 - 0.0019 18.2 2.1 0.0029 17.6 0.0 2.2 2 0 0 2 2 2 1 PWI domain zf-CCCH PF00642.19 EER29175.1 - 0.0029 17.2 1.6 0.0054 16.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Antigen_Bd37 PF11641.3 EER29175.1 - 0.032 13.5 1.2 0.065 12.5 0.8 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein AAA_13 PF13166.1 EER29175.1 - 0.44 8.9 9.1 0.62 8.4 6.3 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EER29175.1 - 8.6 3.5 17.1 12 3.1 11.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) adh_short PF00106.20 EER29177.1 - 5.2e-29 101.3 0.0 6.6e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER29177.1 - 7.8e-20 71.6 0.0 1.1e-19 71.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER29177.1 - 1.7e-07 31.1 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EER29177.1 - 0.00091 18.9 0.9 0.0035 17.1 0.7 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EER29177.1 - 0.00095 18.6 0.0 0.02 14.3 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EER29177.1 - 0.025 13.6 0.0 0.061 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GTP_EFTU PF00009.22 EER29179.1 - 7.1e-62 208.1 0.1 9.8e-62 207.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EER29179.1 - 6.3e-38 129.0 0.0 1.8e-37 127.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EER29179.1 - 8.1e-23 80.1 0.0 2.3e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EER29179.1 - 3.5e-12 45.9 0.0 8.5e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EER29179.1 - 4.8e-12 45.8 0.1 2e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EER29179.1 - 5.4e-05 23.1 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 EER29181.1 - 1.4e-99 332.8 6.4 1.8e-99 332.4 4.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Dynactin PF12455.3 EER29183.1 - 7.1e-92 307.1 4.5 7.1e-92 307.1 3.1 3.8 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EER29183.1 - 8.1e-24 83.1 0.0 1.4e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain HCMV_UL139 PF12507.3 EER29183.1 - 0.73 9.9 15.0 0.34 11.0 1.6 4.0 2 2 1 3 3 3 0 Human Cytomegalovirus UL139 protein HALZ PF02183.13 EER29183.1 - 2.5 7.8 34.0 0.1 12.3 0.4 7.7 5 2 2 8 8 8 0 Homeobox associated leucine zipper Hemerythrin PF01814.18 EER29184.1 - 3e-09 37.1 0.3 3.9e-09 36.7 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAD_2 PF13419.1 EER29185.1 - 9.2e-27 94.3 0.2 1.2e-26 94.0 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EER29185.1 - 0.00012 21.6 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EER29185.1 - 0.015 15.6 0.0 0.019 15.4 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase KH_1 PF00013.24 EER29187.1 - 9.8e-31 105.2 0.1 8.4e-08 31.7 0.2 7.9 8 0 0 8 8 8 6 KH domain KH_3 PF13014.1 EER29187.1 - 6.8e-25 86.2 1.4 0.00025 20.6 0.2 7.3 7 0 0 7 7 7 5 KH domain SUV3_C PF12513.3 EER29187.1 - 0.36 10.3 0.9 0.82 9.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal Chitin_synth_2 PF03142.10 EER29188.1 - 3.9e-256 850.5 0.4 5.3e-256 850.1 0.3 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EER29188.1 - 1.2e-183 611.9 0.0 1.6e-183 611.4 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EER29188.1 - 3.4e-21 74.8 0.0 1.5e-14 53.5 0.0 2.9 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EER29188.1 - 1.4e-18 66.3 1.2 2.4e-17 62.4 0.7 2.7 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EER29188.1 - 3e-15 56.4 5.3 9e-15 54.8 3.7 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EER29188.1 - 7e-14 52.1 0.2 1.3e-10 41.5 0.1 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EER29188.1 - 4.5e-05 23.1 0.0 0.0041 16.8 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EER29188.1 - 0.0027 17.0 0.1 0.023 13.9 0.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 21 AAA_16 PF13191.1 EER29188.1 - 0.0033 17.4 0.1 0.0089 16.0 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EER29188.1 - 0.02 14.0 0.0 0.23 10.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EER29188.1 - 0.038 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Chitin_synth_2 PF03142.10 EER29189.1 - 1.8e-228 759.2 0.0 2.3e-228 758.9 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EER29189.1 - 5.1e-65 219.8 0.0 2.2e-64 217.7 0.0 1.9 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EER29189.1 - 1.5e-22 79.1 0.5 2.1e-13 49.8 0.1 2.6 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EER29189.1 - 8.8e-17 61.4 1.7 8.8e-17 61.4 1.2 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EER29189.1 - 2.3e-16 59.3 1.1 1.4e-15 56.8 0.6 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EER29189.1 - 3.2e-14 53.2 0.0 6.7e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EER29189.1 - 1.1e-05 24.7 0.0 2.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EER29189.1 - 0.0017 18.0 0.0 0.061 12.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 PLDc_2 PF13091.1 EER29190.1 - 4.3e-20 71.7 0.0 2.8e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EER29190.1 - 1.6e-06 27.6 0.0 0.078 12.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Regulator_TrmB PF11495.3 EER29190.1 - 0.0056 15.6 0.0 0.34 9.8 0.0 2.3 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB TPP_enzyme_N PF02776.13 EER29191.1 - 2e-41 141.3 0.0 7.4e-41 139.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EER29191.1 - 2.1e-23 82.6 0.0 9.9e-23 80.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EER29191.1 - 2.4e-20 72.6 0.4 5.8e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF4248 PF14053.1 EER29191.1 - 0.037 13.6 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) NTP_transf_3 PF12804.2 EER29191.1 - 0.11 12.6 0.6 0.54 10.3 0.1 2.4 2 1 1 3 3 3 0 MobA-like NTP transferase domain TatD_DNase PF01026.16 EER29192.1 - 1.9e-37 128.8 0.0 2.6e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Abhydrolase_6 PF12697.2 EER29194.1 - 7e-28 98.0 3.0 7e-28 98.0 2.1 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER29194.1 - 1.3e-15 57.5 0.1 1.5e-12 47.6 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EER29194.1 - 1.5e-13 50.7 0.0 3.5e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EER29194.1 - 0.00014 21.3 0.0 0.00031 20.2 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EER29194.1 - 0.0012 19.1 0.3 0.013 15.7 0.2 2.5 1 1 0 1 1 1 1 Thioesterase domain DUF915 PF06028.6 EER29194.1 - 0.0012 17.9 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EER29194.1 - 0.0038 16.8 0.0 0.037 13.6 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) Chlorophyllase2 PF12740.2 EER29194.1 - 0.004 16.0 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EER29194.1 - 0.006 16.4 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EER29194.1 - 0.0066 16.0 0.0 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EER29194.1 - 0.011 15.4 0.0 0.089 12.3 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase PF07224.6 EER29194.1 - 0.093 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_2 PF02230.11 EER29194.1 - 0.096 12.1 0.0 8.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EER29194.1 - 0.18 11.2 0.0 0.57 9.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Spo7 PF03907.8 EER29195.1 - 1.2e-67 227.6 0.0 1.6e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Zip PF02535.17 EER29195.1 - 2.1 7.2 3.4 0.79 8.6 0.1 1.8 1 1 1 2 2 2 0 ZIP Zinc transporter MCM PF00493.18 EER29196.1 - 3e-129 430.5 0.3 4.2e-129 430.0 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EER29196.1 - 4.3e-17 62.7 0.0 1.1e-16 61.3 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EER29196.1 - 4.7e-07 29.1 0.0 5.7e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EER29196.1 - 0.0031 17.1 0.0 0.0069 15.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3827 PF12877.2 EER29196.1 - 0.054 11.6 11.2 0.081 11.0 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Sigma54_activat PF00158.21 EER29196.1 - 0.061 12.7 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PPR_2 PF13041.1 EER29197.1 - 3.6e-21 74.8 1.3 6.6e-12 45.2 0.0 6.7 4 2 4 8 8 8 4 PPR repeat family PPR_3 PF13812.1 EER29197.1 - 8.6e-19 66.1 0.2 0.00023 21.1 0.0 9.0 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.15 EER29197.1 - 9.5e-16 56.6 8.3 0.00015 21.5 0.0 9.1 10 0 0 10 10 10 4 PPR repeat PPR_1 PF12854.2 EER29197.1 - 7.6e-11 41.2 3.4 0.01 15.2 0.0 5.4 6 0 0 6 6 6 3 PPR repeat VitD-bind_III PF09164.5 EER29198.1 - 0.1 12.1 0.2 0.45 10.1 0.1 2.1 1 0 0 1 1 1 0 Vitamin D binding protein, domain III p450 PF00067.17 EER29199.1 - 5.1e-56 190.1 0.0 7.5e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Mucin PF01456.12 EER29200.1 - 4.4 7.0 11.7 6.2 6.6 8.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Rhodanese PF00581.15 EER29201.1 - 2.1e-10 40.9 0.0 3.8e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain GTP_EFTU PF00009.22 EER29202.1 - 6.2e-33 113.8 0.0 2.9e-32 111.6 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EER29202.1 - 6.1e-19 67.9 0.1 1.5e-18 66.6 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EER29202.1 - 1.1e-11 44.6 1.7 1.7e-09 37.6 0.0 3.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EER29202.1 - 3.9e-06 26.7 0.1 1.4e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EER29202.1 - 0.0014 19.1 1.6 0.0037 17.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EER29202.1 - 0.0022 17.6 0.0 0.0085 15.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu domain 4 ATP_bind_1 PF03029.12 EER29202.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMS1_N PF10433.4 EER29203.1 - 4.6e-129 430.8 0.0 2.3e-127 425.1 0.0 2.1 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EER29203.1 - 1.6e-09 37.2 0.0 2.3e-08 33.5 0.0 2.8 2 2 0 3 3 3 1 CPSF A subunit region EBV-NA1 PF02905.9 EER29203.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain PQQ_3 PF13570.1 EER29203.1 - 0.073 13.3 0.3 24 5.3 0.1 4.3 3 0 0 3 3 3 0 PQQ-like domain RabGAP-TBC PF00566.13 EER29204.1 - 1.6e-25 89.8 0.0 2.4e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DAO PF01266.19 EER29205.1 - 9.7e-58 195.7 0.1 1.1e-57 195.6 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER29205.1 - 4.6e-06 26.5 0.5 1.2e-05 25.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EER29205.1 - 0.0039 17.2 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER29205.1 - 0.019 14.8 0.2 0.031 14.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EER29205.1 - 0.02 13.8 0.4 1.9 7.2 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EER29205.1 - 0.036 13.1 2.2 0.044 12.8 1.5 1.3 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EER29205.1 - 0.037 13.1 0.1 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EER29205.1 - 0.043 12.8 0.3 0.09 11.8 0.2 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EER29205.1 - 0.54 9.0 5.9 3.6 6.3 4.1 1.9 1 1 0 1 1 1 0 FAD binding domain adh_short PF00106.20 EER29205.1 - 3.1 7.6 5.1 0.42 10.5 0.4 1.8 2 0 0 2 2 2 0 short chain dehydrogenase APH PF01636.18 EER29206.1 - 0.00015 21.5 0.0 0.00037 20.3 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Vps52 PF04129.7 EER29207.1 - 9.7e-122 407.0 0.2 1.3e-121 406.5 0.1 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EER29207.1 - 2.7e-05 22.5 1.1 9.8e-05 20.6 0.8 1.9 1 1 0 1 1 1 1 Exocyst complex component Sec3 THOC7 PF05615.8 EER29207.1 - 0.17 12.1 3.2 0.55 10.5 1.1 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 IncA PF04156.9 EER29207.1 - 2.4 7.7 8.9 0.35 10.4 2.5 2.1 2 0 0 2 2 2 0 IncA protein eIF-5a PF01287.15 EER29208.1 - 3.8e-27 94.0 1.5 5.5e-27 93.5 1.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EER29208.1 - 0.00081 19.0 0.3 0.0018 17.9 0.2 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EER29208.1 - 0.0023 17.7 0.2 0.0086 15.9 0.0 2.0 3 0 0 3 3 3 1 Elongation factor P (EF-P) KOW-like domain ubiquitin PF00240.18 EER29209.1 - 5e-34 115.5 3.5 6e-34 115.2 0.6 2.0 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.12 EER29209.1 - 2.5e-30 103.8 11.3 3.9e-30 103.2 7.9 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 EER29209.1 - 6.6e-18 64.1 0.3 1.3e-17 63.2 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EER29209.1 - 3.2e-05 24.1 0.1 0.00011 22.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EER29209.1 - 0.0035 17.0 0.1 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EER29209.1 - 0.026 14.3 0.0 0.057 13.3 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EER29209.1 - 0.029 14.5 0.1 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Yip1 PF04893.12 EER29210.1 - 1.1e-14 54.2 14.2 1.5e-14 53.8 9.7 1.3 1 1 0 1 1 1 1 Yip1 domain RRM_1 PF00076.17 EER29211.1 - 1.1e-81 268.4 7.8 1.8e-23 81.9 0.4 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29211.1 - 1.2e-56 188.5 0.8 4.2e-16 58.6 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29211.1 - 1.7e-40 136.6 0.5 2.5e-09 36.8 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EER29211.1 - 3.1e-31 106.8 2.3 1e-30 105.1 0.8 2.6 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 EER29211.1 - 3.1e-05 23.6 3.3 0.92 9.3 0.1 3.7 3 0 0 3 3 3 3 Limkain b1 RRM_3 PF08777.6 EER29211.1 - 4.4e-05 23.2 8.7 0.12 12.1 0.8 4.9 5 0 0 5 5 5 2 RNA binding motif Nup35_RRM_2 PF14605.1 EER29211.1 - 7.2e-05 22.4 0.4 22 4.8 0.0 4.9 4 1 0 4 4 4 0 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EER29211.1 - 0.00024 21.2 2.5 0.56 10.4 0.0 4.0 3 1 1 4 4 4 2 Cobalamin biosynthesis central region OB_RNB PF08206.6 EER29211.1 - 0.13 11.8 2.9 7.4 6.1 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.20 EER29212.1 - 1.9e-82 276.9 0.0 2.6e-81 273.2 0.0 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EER29212.1 - 0.0015 18.0 0.4 0.0049 16.3 0.2 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif MRP-L27 PF09809.4 EER29213.1 - 2.4e-12 46.4 0.4 2.9e-12 46.1 0.3 1.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.8 EER29214.1 - 2.8e-206 687.0 62.6 2.8e-206 687.0 43.4 2.0 1 1 1 2 2 2 1 Utp14 protein Glyco_hydro_81 PF03639.8 EER29215.1 - 9.3e-203 675.0 0.9 1.1e-202 674.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Na_Ca_ex PF01699.19 EER29216.1 - 7e-45 152.0 38.3 2.2e-23 82.3 8.4 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF1352 PF07086.7 EER29216.1 - 4.3 6.9 8.1 0.15 11.6 1.0 2.0 2 2 0 2 2 2 0 Protein of unknown function (DUF1352) Ribosomal_S7 PF00177.16 EER29217.1 - 2.2e-31 108.4 0.0 5.7e-31 107.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e bZIP_1 PF00170.16 EER29218.1 - 7.9e-10 38.5 2.6 1.5e-09 37.6 1.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EER29218.1 - 1.4e-07 31.1 7.8 2.4e-07 30.4 5.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper DivIC PF04977.10 EER29218.1 - 0.01 15.3 1.8 0.018 14.5 1.3 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_Maf PF03131.12 EER29218.1 - 0.023 14.9 5.5 0.045 14.0 3.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Macoilin PF09726.4 EER29218.1 - 0.04 12.2 2.9 0.042 12.1 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S28 PF05577.7 EER29219.1 - 3.4e-46 157.7 0.0 6.2e-45 153.5 0.0 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EER29219.1 - 0.00079 19.3 0.1 0.0097 15.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER29219.1 - 0.019 14.1 0.0 0.36 10.0 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family GldM_N PF12081.3 EER29219.1 - 0.03 13.8 0.0 0.052 13.0 0.0 1.2 1 0 0 1 1 1 0 GldM N-terminal domain DUF305 PF03713.8 EER29219.1 - 0.21 11.3 0.1 0.37 10.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Methyltransf_2 PF00891.13 EER29220.1 - 1.2e-31 109.7 0.0 1.8e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EER29220.1 - 0.078 13.5 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Vac_Fusion PF02346.11 EER29220.1 - 0.1 12.0 0.0 5.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Chordopoxvirus fusion protein CheR PF01739.13 EER29220.1 - 0.16 11.1 0.0 0.59 9.3 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain SPX PF03105.14 EER29221.1 - 4.5e-46 157.8 0.0 8.6e-46 156.9 0.0 1.5 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EER29221.1 - 2.6e-30 105.7 38.3 3.8e-30 105.1 26.5 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EER29221.1 - 3.7e-13 48.7 42.0 1.5e-12 46.7 15.7 2.4 1 1 1 2 2 2 2 Citrate transporter DUF357 PF04010.8 EER29221.1 - 0.024 14.3 0.1 0.048 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF357) Ribonuclease_T2 PF00445.13 EER29222.1 - 5.1e-47 159.9 2.0 9.5e-47 159.0 1.4 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1792 PF08759.6 EER29222.1 - 0.021 14.4 0.2 0.032 13.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) Ribosomal_S8e PF01201.17 EER29223.1 - 1.9e-47 160.6 1.1 2.2e-47 160.5 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Metallophos PF00149.23 EER29224.1 - 3.2e-09 36.4 3.2 6.8e-09 35.4 2.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER29224.1 - 2.5e-08 33.9 0.0 3.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_20 PF00728.17 EER29225.1 - 3.8e-97 325.6 0.8 4.7e-97 325.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EER29225.1 - 6.1e-20 72.1 0.0 1.3e-19 71.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EER29225.1 - 2.4e-05 24.8 0.0 4.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DOCK-C2 PF14429.1 EER29226.1 - 1.1e-34 119.6 0.0 2.2e-34 118.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EER29226.1 - 2e-13 50.0 0.1 5.1e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EER29226.1 - 9.5e-05 21.7 0.0 0.00022 20.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EER29226.1 - 0.0015 18.0 0.4 0.02 14.4 0.0 2.7 3 0 0 3 3 3 1 Variant SH3 domain Sec3-PIP2_bind PF15277.1 EER29227.1 - 8.5e-30 102.4 0.0 1.5e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C PF09763.4 EER29227.1 - 4.2e-27 94.6 1.0 6.3e-27 94.0 0.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3_C_2 PF15278.1 EER29227.1 - 0.00037 20.5 0.0 0.00069 19.7 0.0 1.4 1 0 0 1 1 1 1 Sec3 exocyst complex subunit SRP40_C PF05022.7 EER29228.1 - 7.7e-21 74.3 0.5 2.5e-20 72.7 0.4 1.9 1 0 0 1 1 1 1 SRP40, C-terminal domain F-box-like PF12937.2 EER29229.1 - 2e-06 27.3 0.4 6.4e-06 25.7 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EER29229.1 - 5.2e-05 22.7 0.3 0.00012 21.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain Antimicrobial10 PF08105.6 EER29229.1 - 0.13 11.8 0.1 0.31 10.6 0.1 1.6 1 0 0 1 1 1 0 Metchnikowin family p450 PF00067.17 EER29230.1 - 1.3e-54 185.4 0.0 1.9e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CHCH PF06747.8 EER29231.1 - 0.016 15.1 1.4 0.033 14.1 0.7 1.7 1 1 1 2 2 2 0 CHCH domain DUF1903 PF08991.5 EER29231.1 - 0.026 14.6 1.6 0.038 14.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) DB PF01682.14 EER29231.1 - 0.054 13.5 0.6 0.065 13.2 0.4 1.1 1 0 0 1 1 1 0 DB module Cmc1 PF08583.5 EER29231.1 - 0.093 12.5 1.1 0.12 12.1 0.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1992 PF09350.5 EER29232.1 - 1.4e-22 79.2 0.2 4.2e-22 77.7 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) adh_short_C2 PF13561.1 EER29234.1 - 1.9e-31 109.6 0.3 2.3e-31 109.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER29234.1 - 1.2e-28 100.0 2.3 1.9e-28 99.5 1.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER29234.1 - 6.4e-08 32.4 0.9 9.4e-08 31.9 0.7 1.4 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 EER29234.1 - 1.6e-06 28.1 0.5 3.1e-06 27.1 0.4 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EER29234.1 - 1e-05 24.3 0.5 1.4e-05 23.9 0.4 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EER29234.1 - 2e-05 24.1 0.3 0.00011 21.7 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EER29234.1 - 2.4e-05 23.5 0.9 3.8e-05 22.8 0.7 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EER29234.1 - 6.7e-05 22.6 1.3 0.00011 21.9 0.9 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EER29234.1 - 0.0002 20.3 0.2 0.00028 19.8 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 EER29234.1 - 0.0012 19.2 0.0 0.0025 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain F420_oxidored PF03807.12 EER29234.1 - 0.0014 19.0 0.2 0.0029 17.9 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EER29234.1 - 0.0044 17.0 0.4 0.0089 16.0 0.3 1.5 1 0 0 1 1 1 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 EER29234.1 - 0.0052 16.1 0.3 0.0098 15.2 0.1 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.1 EER29234.1 - 0.0058 16.2 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ldh_1_N PF00056.18 EER29234.1 - 0.024 14.4 0.9 0.045 13.5 0.6 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EER29234.1 - 0.025 14.3 0.1 0.05 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EER29234.1 - 0.053 12.9 0.1 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA MTS PF05175.9 EER29234.1 - 0.12 11.7 0.5 0.22 10.8 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EER29234.1 - 0.51 10.3 2.3 2 8.4 1.6 2.1 1 1 0 1 1 1 0 Methyltransferase domain DUF3481 PF11980.3 EER29235.1 - 0.15 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Acetyltransf_8 PF13523.1 EER29238.1 - 1.5e-43 148.2 0.0 2.2e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EER29238.1 - 0.047 13.8 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L15e PF00827.12 EER29239.1 - 1.1e-91 305.6 11.4 1.2e-91 305.4 7.9 1.0 1 0 0 1 1 1 1 Ribosomal L15 DUF2458 PF10454.4 EER29240.1 - 0.18 11.6 3.9 0.38 10.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) Cut12 PF11500.3 EER29240.1 - 1.7 8.3 9.6 0.19 11.4 2.0 2.2 2 1 0 2 2 2 0 Spindle pole body formation-associated protein PSP1 PF04468.7 EER29241.1 - 1.9e-30 104.6 1.7 3.2e-30 103.9 1.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Nfu_N PF08712.6 EER29242.1 - 8.8e-27 92.5 0.0 2.9e-26 90.9 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EER29242.1 - 1.2e-22 79.4 0.1 1.9e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 EER29242.1 - 0.028 14.2 0.2 0.059 13.2 0.1 1.6 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus RasGEF PF00617.14 EER29243.1 - 4.5e-46 156.9 1.8 5.5e-46 156.6 0.2 2.0 3 0 0 3 3 3 1 RasGEF domain Miro PF08477.8 EER29243.1 - 2.5e-12 47.3 0.0 5.8e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein RasGEF_N PF00618.15 EER29243.1 - 3.7e-10 39.8 0.0 1.3e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif Ras PF00071.17 EER29243.1 - 0.0012 18.2 0.0 0.0057 16.0 0.0 2.1 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.1 EER29243.1 - 0.0063 16.5 0.1 0.17 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EER29243.1 - 0.019 15.1 0.1 0.5 10.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EER29243.1 - 0.051 13.0 0.3 0.41 10.0 0.0 2.5 3 1 0 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.18 EER29243.1 - 0.077 12.9 0.0 0.29 11.0 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EER29243.1 - 0.099 12.1 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EER29243.1 - 0.14 11.5 0.0 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-HIT PF04438.11 EER29244.1 - 5e-09 35.6 7.9 8.5e-09 34.9 5.5 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-B_box PF00643.19 EER29244.1 - 4.3 7.3 10.0 7.2 6.5 6.9 1.4 1 0 0 1 1 1 0 B-box zinc finger Complex1_LYR_2 PF13233.1 EER29245.1 - 4.5e-22 78.5 0.3 5.2e-22 78.3 0.2 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Cyclin_N PF00134.18 EER29246.1 - 2e-11 43.5 0.0 3.7e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EER29246.1 - 1.6e-08 35.0 0.0 2.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin Pkinase PF00069.20 EER29247.1 - 2.4e-09 36.7 1.8 1.1e-07 31.3 1.2 2.1 1 1 0 1 1 1 1 Protein kinase domain MFS_1 PF07690.11 EER29249.1 - 7.8e-32 110.3 66.5 1.2e-25 89.9 27.5 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily SBF PF01758.11 EER29250.1 - 1.3e-50 171.3 10.9 1.3e-50 171.3 7.6 2.6 2 2 1 3 3 3 1 Sodium Bile acid symporter family ATP_bind_3 PF01171.15 EER29251.1 - 3.4e-19 69.0 0.0 6.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 PP-loop family tRNA_Me_trans PF03054.11 EER29251.1 - 0.0029 16.2 0.0 0.0044 15.6 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase RecR PF02132.10 EER29251.1 - 0.0057 16.0 1.2 0.0057 16.0 0.8 2.9 3 0 0 3 3 3 1 RecR protein DUF2392 PF10288.4 EER29251.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) zf-UBR PF02207.15 EER29251.1 - 0.19 11.4 6.7 3.6 7.3 0.4 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) HECT PF00632.20 EER29252.1 - 8.8e-73 245.2 0.0 1.2e-72 244.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HXXSHH PF07586.6 EER29252.1 - 0.036 12.9 0.1 0.061 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) ADH_N PF08240.7 EER29253.1 - 5.8e-36 122.5 3.7 1.2e-35 121.5 1.8 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER29253.1 - 5.5e-16 58.3 0.0 8.8e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EER29253.1 - 0.0041 17.6 0.0 0.0096 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Gp_dh_N PF00044.19 EER29253.1 - 0.021 14.7 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EER29253.1 - 0.045 12.7 0.5 0.074 12.0 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_3 PF03447.11 EER29253.1 - 0.086 13.2 0.0 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain FRG1 PF06229.7 EER29254.1 - 9.1e-60 201.3 0.1 1.3e-59 200.8 0.1 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EER29254.1 - 0.0061 16.6 0.0 0.04 14.0 0.0 2.2 2 0 0 2 2 2 1 Fascin domain zf-RING_2 PF13639.1 EER29255.1 - 1.1e-13 50.7 5.1 2.1e-13 49.8 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EER29255.1 - 1.2e-06 28.3 5.5 1.2e-06 28.3 3.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER29255.1 - 1.3e-06 28.0 3.4 2.3e-06 27.1 2.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EER29255.1 - 1.3e-05 24.7 4.4 2.3e-05 23.9 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EER29255.1 - 1.6e-05 24.9 1.5 3.7e-05 23.7 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EER29255.1 - 5.8e-05 22.6 2.6 0.00011 21.7 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EER29255.1 - 0.0021 17.8 1.7 0.0044 16.8 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EER29255.1 - 0.035 13.8 2.4 0.067 12.9 0.3 2.3 1 1 1 2 2 2 0 RING-type zinc-finger Prok-RING_1 PF14446.1 EER29255.1 - 0.13 12.0 1.0 2.5 7.9 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 EER29255.1 - 0.2 11.3 2.6 0.38 10.4 1.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.1 EER29255.1 - 0.26 11.2 5.9 0.71 9.8 4.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EER29255.1 - 0.36 10.3 3.8 0.93 9.0 2.6 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.2 EER29255.1 - 0.39 10.7 1.6 0.67 10.0 1.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.6 EER29255.1 - 1.5 8.8 3.8 0.75 9.8 0.8 1.8 2 0 0 2 2 2 0 RING-like domain zf-P11 PF03854.9 EER29255.1 - 1.6 8.2 5.0 0.28 10.6 0.6 1.8 2 0 0 2 2 2 0 P-11 zinc finger Ada3 PF10198.4 EER29256.1 - 4.3e-43 146.1 0.0 8.6e-43 145.2 0.0 1.5 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 NPR2 PF06218.6 EER29257.1 - 1.1e-132 442.7 0.0 3.2e-132 441.2 0.0 1.6 2 0 0 2 2 2 1 Nitrogen permease regulator 2 Fungal_trans PF04082.13 EER29258.1 - 1.3e-10 40.6 0.2 2e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29258.1 - 8.5e-06 25.5 10.7 2e-05 24.4 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EER29258.1 - 0.0012 19.0 26.5 0.021 15.1 5.6 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER29258.1 - 0.0017 18.5 12.5 0.027 14.7 4.5 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER29258.1 - 0.004 17.3 26.0 0.06 13.7 2.7 3.9 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EER29258.1 - 0.2 11.8 0.1 0.2 11.8 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding p450 PF00067.17 EER29259.1 - 5.7e-75 252.6 0.0 7.1e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lactamase_B_2 PF12706.2 EER29261.1 - 1.8e-11 43.9 0.0 3.7e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EER29261.1 - 2.1e-07 30.9 0.2 7e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 EER29261.1 - 6.9e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Amidohydro_1 PF01979.15 EER29262.1 - 9.4e-63 212.8 1.2 1.5e-62 212.2 0.9 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EER29262.1 - 2.3e-54 182.6 1.4 2.3e-54 182.6 1.0 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EER29262.1 - 7.4e-41 138.0 0.2 1.2e-39 134.1 0.0 2.3 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EER29262.1 - 3.3e-37 126.4 0.2 6.8e-37 125.4 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EER29262.1 - 1.5e-07 31.1 1.5 3.9e-07 29.7 1.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EER29262.1 - 2.3e-06 27.0 1.2 3.4e-05 23.2 0.0 2.3 1 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EER29262.1 - 0.00078 19.5 0.1 0.4 10.6 0.1 2.6 2 0 0 2 2 2 2 Amidohydrolase HMG_box PF00505.14 EER29263.1 - 1.8e-08 34.5 3.6 1.8e-08 34.5 2.5 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EER29263.1 - 5.7e-06 26.6 3.0 5.7e-06 26.6 2.1 2.1 2 0 0 2 2 2 1 HMG-box domain NAD_binding_1 PF00175.16 EER29264.1 - 3.2e-31 108.1 0.0 5e-31 107.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EER29264.1 - 6.8e-22 77.4 0.0 1.5e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EER29264.1 - 4.7e-10 39.5 0.0 9.8e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EER29264.1 - 0.00045 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF533 PF04391.7 EER29264.1 - 0.18 11.1 0.4 0.29 10.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Ribosomal_L18ae PF01775.12 EER29265.1 - 4.8e-48 162.1 3.0 5.9e-48 161.8 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 EER29266.1 - 5.2e-06 26.7 0.0 0.00069 19.8 0.0 2.8 3 0 0 3 3 3 1 PCI domain Peptidase_M76 PF09768.4 EER29266.1 - 0.12 11.8 0.0 0.28 10.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase M76 family BTB PF00651.26 EER29267.1 - 5.3e-06 26.3 0.0 2.1e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain tRNA-synt_2 PF00152.15 EER29268.1 - 4.1e-79 265.7 0.0 5.2e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EER29268.1 - 9.1e-10 38.2 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EER29268.1 - 8.6e-07 28.3 0.2 0.012 14.8 0.0 3.6 4 0 0 4 4 4 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EER29268.1 - 0.08 12.5 0.0 9.6 5.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 EER29269.1 - 1.3e-24 85.2 1.6 1.5e-24 85.0 1.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PG_binding_1 PF01471.13 EER29270.1 - 0.033 14.1 0.0 1.4 8.9 0.0 2.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain TMPIT PF07851.8 EER29270.1 - 0.29 10.1 0.2 0.5 9.3 0.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein CLTH PF10607.4 EER29271.1 - 7.2e-33 113.3 0.0 1.3e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EER29271.1 - 4e-18 64.8 0.4 8.8e-18 63.7 0.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EER29271.1 - 5.4e-05 22.5 0.2 0.00018 20.8 0.0 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EER29271.1 - 0.00023 20.9 0.2 0.00044 20.0 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EER29271.1 - 0.00092 19.1 0.4 0.0017 18.3 0.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER29271.1 - 0.0011 18.6 0.1 0.0019 17.8 0.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EER29271.1 - 0.017 14.8 0.3 0.029 14.0 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EER29271.1 - 0.077 12.6 0.3 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SAD_SRA PF02182.12 EER29272.1 - 5.2e-20 71.3 0.1 8.5e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain 2OG-FeII_Oxy PF03171.15 EER29273.1 - 0.00061 20.0 0.0 0.0011 19.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EER29274.1 - 3.3e-75 253.3 0.0 4.1e-75 253.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_antitermQ PF06530.7 EER29274.1 - 0.15 11.5 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Phage antitermination protein Q Clr2 PF10383.4 EER29275.1 - 1.9e-30 105.6 0.0 9.4e-30 103.4 0.0 2.2 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 p450 PF00067.17 EER29276.1 - 9.9e-20 70.4 0.4 8.9e-19 67.3 0.0 2.5 3 1 0 3 3 3 1 Cytochrome P450 ABC_membrane_2 PF06472.10 EER29277.1 - 1.1e-93 313.4 0.1 2.2e-93 312.4 0.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EER29277.1 - 2.4e-13 50.5 0.0 6.1e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EER29277.1 - 0.00084 18.8 0.1 0.28 10.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 EER29277.1 - 0.02 15.1 0.1 0.064 13.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER29277.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EER29277.1 - 0.027 15.3 0.3 0.1 13.4 0.2 2.1 1 1 0 1 1 1 0 AAA domain ALIX_LYPXL_bnd PF13949.1 EER29277.1 - 0.14 11.1 0.1 0.23 10.3 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Mg_chelatase PF01078.16 EER29277.1 - 0.15 11.2 0.5 0.26 10.4 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NIF PF03031.13 EER29278.1 - 4.8e-52 175.8 0.4 6.7e-52 175.3 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.2 EER29279.1 - 2e-39 132.5 34.0 6.8e-11 41.5 1.3 6.2 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER29279.1 - 1.3e-19 69.6 39.3 4.9e-07 29.3 5.3 5.3 3 1 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EER29279.1 - 9.3e-14 49.3 32.5 0.08 13.0 0.9 10.2 9 1 1 10 10 10 5 Leucine Rich Repeat LRR_6 PF13516.1 EER29279.1 - 2.2e-11 42.5 29.1 0.063 13.3 1.0 9.7 5 1 5 10 10 10 5 Leucine Rich repeat LRR_7 PF13504.1 EER29279.1 - 8.6e-11 40.2 28.9 0.9 10.0 0.3 9.8 10 0 0 10 10 10 4 Leucine rich repeat LRR_9 PF14580.1 EER29279.1 - 5.4e-10 39.1 10.0 0.00051 19.6 0.6 3.1 1 1 2 3 3 3 3 Leucine-rich repeat Pkip-1 PF06878.6 EER29279.1 - 0.58 10.0 7.4 0.57 10.0 0.1 2.8 3 1 0 3 3 3 0 Pkip-1 protein Aldo_ket_red PF00248.16 EER29281.1 - 1.9e-49 168.0 0.0 2.2e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RecR PF02132.10 EER29282.1 - 0.088 12.2 3.0 0.7 9.3 0.2 2.3 2 0 0 2 2 2 0 RecR protein Zn_clus PF00172.13 EER29282.1 - 1.2 9.0 4.7 0.29 11.0 0.5 1.9 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynein_light PF01221.13 EER29283.1 - 1.6e-41 140.1 2.8 1.9e-41 139.9 1.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF3139 PF11337.3 EER29283.1 - 0.049 13.9 0.3 0.081 13.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Viral_DNA_bp PF00747.12 EER29283.1 - 0.094 9.9 0.1 0.11 9.7 0.1 1.0 1 0 0 1 1 1 0 ssDNA binding protein Peptidase_C3 PF00548.15 EER29283.1 - 0.11 12.3 0.1 0.13 12.1 0.0 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) RRM_1 PF00076.17 EER29284.1 - 7e-71 233.8 1.2 4.9e-18 64.5 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29284.1 - 2.2e-62 206.9 0.8 3.3e-13 49.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29284.1 - 2.7e-32 110.4 0.0 1.4e-07 31.2 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER29284.1 - 1.7e-05 24.5 0.0 0.3 10.8 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EER29284.1 - 4.6e-05 23.0 0.3 2.4 7.9 0.0 5.2 5 0 0 5 5 5 2 Limkain b1 RRM_2 PF04059.7 EER29284.1 - 0.01 15.8 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif 2 RRM_3 PF08777.6 EER29284.1 - 0.47 10.3 3.2 5.5 6.8 0.0 3.9 5 0 0 5 5 5 0 RNA binding motif Sec61_beta PF03911.11 EER29285.1 - 1.1e-19 69.9 0.9 1.4e-19 69.5 0.6 1.2 1 0 0 1 1 1 1 Sec61beta family Mit_proteolip PF08039.6 EER29286.1 - 0.0077 16.1 0.6 0.06 13.3 0.4 2.3 1 1 0 1 1 1 1 Mitochondrial proteolipid DUF1129 PF06570.6 EER29286.1 - 0.53 9.5 10.7 0.041 13.1 3.3 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) RCR PF12273.3 EER29286.1 - 3.3 8.2 5.8 0.86 10.1 0.3 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red PCNA_N PF00705.13 EER29287.1 - 5.7e-54 181.0 4.0 6.8e-54 180.7 1.9 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EER29287.1 - 8.6e-51 171.1 0.0 1.9e-50 170.0 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EER29287.1 - 4.4e-09 35.8 0.0 5.3e-09 35.5 0.0 1.0 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 EER29287.1 - 0.0035 16.3 0.3 0.02 13.8 0.1 2.0 1 1 1 2 2 2 1 Hus1-like protein FliW PF02623.10 EER29287.1 - 0.048 13.2 0.1 0.23 11.0 0.1 2.1 2 0 0 2 2 2 0 FliW protein Vezatin PF12632.2 EER29288.1 - 2e-50 171.2 0.2 3.3e-50 170.5 0.2 1.4 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF1084 PF06454.6 EER29288.1 - 0.0078 15.2 0.4 0.011 14.7 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Metallophos PF00149.23 EER29289.1 - 6.7e-45 152.9 0.2 8.2e-45 152.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 EER29290.1 - 1.3e-60 203.5 0.0 1.5e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EER29290.1 - 2.7e-09 36.2 0.1 2.2e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EER29290.1 - 8.4e-08 32.1 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EER29290.1 - 1.3e-07 32.0 0.0 1.8e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EER29290.1 - 5e-07 29.0 0.0 6.5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EER29290.1 - 0.00027 20.3 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EER29290.1 - 0.0032 16.6 0.0 0.0037 16.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region CENP-M PF11111.3 EER29290.1 - 0.036 13.3 0.0 0.078 12.2 0.0 1.5 2 0 0 2 2 2 0 Centromere protein M (CENP-M) GTP_EFTU PF00009.22 EER29290.1 - 0.051 13.0 0.0 1.2 8.5 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EER29290.1 - 0.076 12.5 0.1 0.22 11.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF2457 PF10446.4 EER29291.1 - 1.3e-156 521.8 28.7 2.5e-156 521.0 19.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CH PF00307.26 EER29293.1 - 5.3e-05 23.2 0.0 0.073 13.1 0.0 3.2 2 1 0 2 2 2 2 Calponin homology (CH) domain IQ PF00612.22 EER29293.1 - 0.064 12.9 0.4 0.19 11.4 0.3 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif CAMSAP_CH PF11971.3 EER29293.1 - 0.1 12.2 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 CAMSAP CH domain LRR_4 PF12799.2 EER29294.1 - 5.8e-15 54.5 3.5 7.9e-07 28.5 0.7 4.8 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER29294.1 - 2e-12 46.6 1.6 2.4e-06 27.1 0.5 3.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EER29294.1 - 2.3e-08 32.9 6.6 0.16 12.1 0.1 6.2 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.1 EER29294.1 - 0.00075 19.3 5.2 3 8.1 0.1 4.8 3 1 1 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 EER29294.1 - 0.001 18.9 6.4 16 6.2 0.2 6.1 6 1 1 7 7 7 2 Leucine rich repeat DUF3336 PF11815.3 EER29295.1 - 5.1e-48 162.2 1.2 7.9e-48 161.6 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EER29295.1 - 3.7e-20 72.7 0.0 1.9e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1206 PF06724.6 EER29295.1 - 0.079 12.7 0.0 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) TPR_11 PF13414.1 EER29296.1 - 3.4e-21 74.6 20.7 5.3e-05 22.7 0.0 7.7 7 1 0 8 8 8 4 TPR repeat TPR_19 PF14559.1 EER29296.1 - 4.6e-19 68.5 16.8 2.8e-07 30.7 0.0 7.3 6 2 2 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.1 EER29296.1 - 4.6e-16 58.9 13.1 5.1e-05 23.8 0.0 6.7 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EER29296.1 - 1e-15 56.7 17.5 0.0014 19.0 0.3 8.0 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EER29296.1 - 2.8e-13 48.9 9.6 0.092 12.9 0.0 8.7 10 0 0 10 10 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EER29296.1 - 3.5e-10 39.0 30.6 0.08 12.8 0.1 10.3 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 EER29296.1 - 4.2e-09 35.5 17.5 0.15 11.8 0.0 9.3 9 2 0 9 9 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EER29296.1 - 4.5e-09 36.3 21.4 0.0076 16.3 0.0 6.6 6 1 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EER29296.1 - 1.4e-08 34.5 23.6 0.02 14.8 0.9 7.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EER29296.1 - 4.6e-07 29.1 18.1 0.44 10.2 0.0 9.0 10 1 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EER29296.1 - 9.2e-07 28.2 3.9 2.6 8.0 0.0 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 EER29296.1 - 0.00063 19.8 10.5 3.1 7.9 0.0 5.6 3 1 1 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.3 EER29296.1 - 0.0034 16.1 5.9 0.35 9.5 0.6 3.3 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 RPN7 PF10602.4 EER29296.1 - 0.011 15.1 4.1 2.2 7.6 0.0 4.0 4 1 0 4 4 4 0 26S proteasome subunit RPN7 BTAD PF03704.12 EER29296.1 - 0.019 15.2 2.4 0.04 14.2 0.4 2.6 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Alkyl_sulf_dimr PF14863.1 EER29296.1 - 0.046 13.9 4.2 1.7 8.8 0.1 3.5 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation NatB_MDM20 PF09797.4 EER29296.1 - 0.051 12.2 0.2 5 5.7 0.0 2.4 2 0 0 2 2 2 0 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_6 PF13174.1 EER29296.1 - 4.7 7.8 18.5 5.2 7.7 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EER29296.1 - 6.4 6.6 14.6 1.2 8.9 0.4 5.2 5 1 2 7 7 7 0 Tetratricopeptide repeat SAM_2 PF07647.12 EER29297.1 - 1.9e-09 37.2 0.2 3.7e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EER29297.1 - 2.6e-05 24.2 0.2 5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DHC_N1 PF08385.7 EER29297.1 - 0.25 9.6 4.5 1.9 6.7 3.3 2.0 1 1 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Rab5ip PF07019.7 EER29298.1 - 6.3e-08 32.6 10.2 4.9e-07 29.7 7.0 2.0 1 1 0 1 1 1 1 Rab5-interacting protein (Rab5ip) MFS_1 PF07690.11 EER29299.1 - 5.3e-25 87.8 61.6 2.7e-23 82.2 38.5 3.6 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER29299.1 - 1.1e-12 47.0 13.3 1.1e-12 47.0 9.3 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EER29299.1 - 1e-06 27.6 9.6 1e-06 27.6 6.7 3.3 2 1 1 3 3 3 1 Sugar (and other) transporter Sulfate_transp PF00916.15 EER29301.1 - 3.2e-75 252.7 3.6 6.7e-75 251.6 2.5 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EER29301.1 - 1.5e-31 107.9 1.8 1.5e-31 107.9 1.2 3.6 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EER29301.1 - 6.5e-08 32.0 0.0 1.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain DnaJ PF00226.26 EER29302.1 - 1.8e-25 88.4 3.1 3.2e-25 87.6 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EER29302.1 - 4.9e-22 77.6 0.3 1.9e-19 69.3 0.0 2.6 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EER29302.1 - 4.3e-14 52.3 17.2 7.8e-14 51.4 12.0 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EER29302.1 - 0.041 13.5 8.5 0.18 11.5 1.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 EER29302.1 - 0.93 9.3 4.2 7.9 6.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) zinc-ribbons_6 PF07191.7 EER29302.1 - 1.1 9.1 4.7 13 5.6 0.7 2.3 2 0 0 2 2 2 0 zinc-ribbons URO-D PF01208.12 EER29303.1 - 8.2e-124 412.9 0.0 9.3e-124 412.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.6 EER29303.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Phloem filament protein PP1 WD40 PF00400.27 EER29304.1 - 5.3e-05 22.9 6.5 0.0012 18.6 1.2 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat CPSF_A PF03178.10 EER29304.1 - 0.034 13.2 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 CPSF A subunit region Ribosomal_L10 PF00466.15 EER29305.1 - 5.2e-26 90.4 0.2 1.3e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EER29305.1 - 8.5e-16 58.1 7.2 1.6e-15 57.2 2.5 2.4 2 0 0 2 2 2 1 60s Acidic ribosomal protein Vps53_N PF04100.7 EER29306.1 - 3.5e-105 351.9 10.4 7.1e-105 350.9 7.2 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EER29306.1 - 1.5e-05 24.1 9.6 1.5e-05 24.1 6.7 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EER29306.1 - 0.0033 17.2 0.8 0.014 15.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) DegV PF02645.11 EER29306.1 - 0.055 12.5 3.9 0.059 12.4 0.1 2.6 2 1 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 COG2 PF06148.6 EER29306.1 - 0.23 11.3 6.9 0.18 11.6 3.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1515 PF07439.6 EER29306.1 - 0.37 10.6 8.7 0.054 13.3 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Sporozoite_P67 PF05642.6 EER29306.1 - 1.3 6.7 6.7 2.1 6.1 4.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spc7 PF08317.6 EER29306.1 - 2.8 6.5 15.4 0.46 9.0 7.4 1.9 2 1 1 3 3 3 0 Spc7 kinetochore protein TAP_C PF03943.8 EER29307.1 - 4.1e-13 48.5 0.5 7.8e-13 47.6 0.3 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EER29307.1 - 1.1e-07 31.3 3.1 1.7e-05 24.3 0.4 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EER29307.1 - 7.2e-05 22.4 0.3 0.0002 21.0 0.2 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EER29307.1 - 0.0077 16.1 0.1 4 7.8 0.2 3.7 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_7 PF13504.1 EER29307.1 - 0.022 14.8 1.4 1.2 9.6 0.2 3.4 3 0 0 3 3 3 0 Leucine rich repeat NTF2 PF02136.15 EER29307.1 - 0.027 14.8 0.0 0.069 13.5 0.0 1.8 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain LRR_6 PF13516.1 EER29307.1 - 0.18 11.9 0.8 5.4 7.3 0.2 3.4 4 0 0 4 4 4 0 Leucine Rich repeat COPIIcoated_ERV PF07970.7 EER29308.1 - 3.2e-68 229.6 0.1 2.1e-44 151.7 0.0 2.2 1 1 1 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EER29308.1 - 8.4e-35 118.6 0.0 7e-34 115.6 0.0 2.2 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PH PF00169.24 EER29309.1 - 0.00021 21.4 0.0 0.0022 18.1 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EER29309.1 - 0.00085 19.4 0.0 0.0043 17.1 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain zf-C2H2_4 PF13894.1 EER29310.1 - 5e-25 85.9 52.8 0.0037 17.4 0.0 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-C2H2 PF00096.21 EER29310.1 - 2.6e-24 84.0 60.4 0.00014 21.9 0.4 11.4 10 2 0 10 10 10 9 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER29310.1 - 1.4e-19 69.3 53.3 3.6e-05 23.8 0.4 11.0 11 0 0 11 11 11 7 Zinc-finger double domain GAGA PF09237.6 EER29310.1 - 2.2e-05 23.9 1.4 2.2e-05 23.9 1.0 3.2 4 0 0 4 4 4 1 GAGA factor zf-C2H2_jaz PF12171.3 EER29310.1 - 3.4e-05 23.8 14.7 12 6.2 0.0 8.5 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EER29310.1 - 0.0008 19.5 13.8 20 5.5 0.4 8.1 8 0 0 8 8 8 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 EER29310.1 - 0.002 18.2 0.5 0.002 18.2 0.3 9.0 10 1 1 11 11 11 1 C2H2-type zinc-finger domain CHORD PF04968.7 EER29310.1 - 5.3 7.3 19.1 3.3 8.0 0.6 4.8 3 3 2 5 5 5 0 CHORD RNA_pol_Rpb6 PF01192.17 EER29311.1 - 5.2e-24 83.7 0.2 8.7e-24 83.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 MFS_1 PF07690.11 EER29312.1 - 1.5e-22 79.8 49.2 1.8e-17 63.0 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Hum_adeno_E3A PF05393.6 EER29312.1 - 0.023 14.3 0.2 0.074 12.7 0.2 1.8 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Acetyltransf_1 PF00583.19 EER29313.1 - 6.4e-14 51.7 0.1 8.6e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EER29313.1 - 1.4e-06 27.9 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EER29313.1 - 2.7e-06 27.4 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EER29313.1 - 0.00023 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER29313.1 - 0.00033 20.7 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER29313.1 - 0.021 14.6 0.1 0.039 13.7 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PCI PF01399.22 EER29315.1 - 2.6e-12 46.9 0.5 1e-10 41.8 0.0 3.2 2 0 0 2 2 2 1 PCI domain G-gamma PF00631.17 EER29316.1 - 4.6e-24 83.9 0.1 5.6e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 EER29316.1 - 0.006 16.7 0.0 0.0074 16.4 0.0 1.1 1 0 0 1 1 1 1 Suppressor of RNA silencing P21-like Rdx PF10262.4 EER29317.1 - 3.2e-30 103.9 0.0 4.2e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Rdx family PDEase_I PF00233.14 EER29318.1 - 5.2e-46 157.3 0.0 2.5e-41 141.9 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase DEAD PF00270.24 EER29319.1 - 5.5e-17 61.7 0.2 1.8e-16 60.1 0.1 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER29319.1 - 2.5e-08 33.6 0.1 8.2e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EER29319.1 - 7.3e-06 26.0 0.1 6e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain ResIII PF04851.10 EER29319.1 - 1.7e-05 24.7 0.0 4.4e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Adeno_IVa2 PF02456.10 EER29319.1 - 0.056 12.0 0.0 0.36 9.4 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein FAD_binding_4 PF01565.18 EER29320.1 - 2e-29 101.8 0.0 3.4e-29 101.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EER29320.1 - 5.4e-19 68.4 0.0 8.2e-19 67.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Sugar_tr PF00083.19 EER29321.1 - 2.4e-76 257.1 26.0 3e-76 256.8 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER29321.1 - 6.5e-16 57.9 26.1 6.5e-16 57.9 18.1 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EER29321.1 - 0.95 9.5 7.7 3 7.9 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) p450 PF00067.17 EER29322.1 - 1.9e-57 194.8 0.0 1.4e-54 185.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EER29323.1 - 2.4e-18 65.9 0.0 4.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RPE65 PF03055.10 EER29324.1 - 1.7e-129 432.5 0.0 1.9e-129 432.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Pyr_redox_3 PF13738.1 EER29325.1 - 1.2e-21 77.7 0.0 6.4e-20 72.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER29325.1 - 4.2e-16 58.2 0.0 5.3e-11 41.4 0.1 3.0 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EER29325.1 - 8.2e-10 38.5 0.0 8.2e-10 38.5 0.0 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EER29325.1 - 1.5e-07 30.7 0.1 8.4e-05 21.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EER29325.1 - 1.2e-06 28.5 0.0 0.0027 17.6 0.0 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EER29325.1 - 1.3e-06 27.6 5.9 0.032 13.1 0.2 4.2 1 1 2 3 3 3 3 FAD dependent oxidoreductase GIDA PF01134.17 EER29325.1 - 0.00016 20.6 3.4 0.0062 15.4 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 EER29325.1 - 0.00042 19.4 0.7 0.071 12.1 0.0 3.4 4 0 0 4 4 4 1 Thi4 family NAD_binding_9 PF13454.1 EER29325.1 - 0.0024 17.6 2.9 1.7 8.3 0.0 3.5 4 0 0 4 4 4 2 FAD-NAD(P)-binding Mqo PF06039.10 EER29325.1 - 0.014 13.5 0.1 0.44 8.6 0.1 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Malic_M PF03949.10 EER29325.1 - 0.06 12.8 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 EER29325.1 - 0.081 13.3 1.5 2.6 8.5 0.2 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CoA_binding PF02629.14 EER29325.1 - 0.094 13.2 0.9 8.5 6.9 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain Lycopene_cycl PF05834.7 EER29325.1 - 0.19 10.6 0.0 26 3.5 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_4 PF07993.7 EER29326.1 - 2.3e-40 138.0 0.0 4.1e-40 137.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EER29326.1 - 1.4e-34 119.2 0.0 9e-34 116.5 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EER29326.1 - 8.4e-14 51.5 0.0 1.8e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EER29326.1 - 2.5e-08 34.0 0.0 6.5e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EER29326.1 - 1.9e-06 26.7 0.0 1.3e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EER29326.1 - 0.0015 18.4 0.2 0.03 14.2 0.0 2.6 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EER29326.1 - 0.0027 17.7 0.0 0.033 14.1 0.0 2.4 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EER29326.1 - 0.0051 16.4 0.1 0.068 12.8 0.1 2.4 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EER29326.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EER29326.1 - 0.027 13.3 0.4 0.082 11.7 0.1 1.9 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EER29326.1 - 0.094 12.6 0.0 0.87 9.5 0.0 2.3 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FAA_hydrolase PF01557.13 EER29327.1 - 7.3e-49 166.1 0.0 8.6e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family H_PPase PF03030.11 EER29327.1 - 0.084 11.1 0.1 0.11 10.6 0.0 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Glyoxalase PF00903.20 EER29328.1 - 2e-12 47.2 3.3 2e-10 40.7 0.4 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EER29328.1 - 1.4e-07 32.0 0.9 0.00019 21.9 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EER29328.1 - 0.033 14.2 0.6 0.16 11.9 0.1 2.3 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 EER29329.1 - 1.5e-18 67.0 0.0 2.4e-11 43.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain zf-HC5HC2H_2 PF13832.1 EER29330.1 - 3.7e-23 81.6 2.2 3.7e-23 81.6 1.5 3.9 3 1 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EER29330.1 - 6.9e-21 74.2 3.8 6.9e-21 74.2 2.6 4.7 4 0 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 EER29330.1 - 5.4e-17 61.6 0.0 1e-16 60.7 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EER29330.1 - 1.2e-11 44.1 50.5 6.3e-07 28.9 4.5 5.8 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EER29330.1 - 1.7e-08 33.6 4.1 1.7e-08 33.6 2.8 5.0 6 0 0 6 6 6 2 PHD-finger C1_1 PF00130.17 EER29330.1 - 0.0033 17.0 3.3 0.0033 17.0 2.3 7.1 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Glucosamine_iso PF01182.15 EER29331.1 - 2.7e-58 196.9 0.0 3.2e-58 196.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase NAGLU PF05089.7 EER29331.1 - 0.0042 15.9 0.0 0.0055 15.5 0.0 1.1 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain DUF1524 PF07510.6 EER29332.1 - 4.2e-15 55.8 0.1 5.2e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EER29332.1 - 0.0039 16.7 0.5 0.011 15.3 0.3 1.8 1 1 0 1 1 1 1 HNH endonuclease Vps8 PF12816.2 EER29334.1 - 1e-69 233.7 0.4 2.6e-69 232.3 0.1 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EER29334.1 - 0.00024 20.7 1.1 0.9 9.1 0.0 3.8 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-C3HC4_2 PF13923.1 EER29334.1 - 0.042 13.8 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER29334.1 - 0.1 12.4 2.6 0.24 11.2 0.2 2.6 2 0 0 2 2 2 0 Ring finger domain Pox_D3 PF04580.8 EER29334.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein WD40 PF00400.27 EER29334.1 - 0.12 12.3 0.2 0.4 10.6 0.2 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat Pkinase PF00069.20 EER29335.1 - 5e-05 22.5 0.0 9.3e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EER29335.1 - 0.00013 21.7 0.1 0.00013 21.7 0.1 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EER29335.1 - 0.011 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSDR_N_2 PF13588.1 EER29335.1 - 0.035 13.9 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) RIO1 PF01163.17 EER29335.1 - 0.054 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_16 PF00722.16 EER29336.1 - 5.7e-11 42.0 0.3 8.7e-10 38.1 0.2 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3929 PF13066.1 EER29337.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) APH PF01636.18 EER29338.1 - 2.5e-18 66.6 0.0 3.3e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER29338.1 - 0.00014 21.4 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3435 PF11917.3 EER29339.1 - 9.1e-103 344.1 6.4 2.7e-99 332.7 4.5 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3435) Triabin PF03973.8 EER29340.1 - 0.021 14.5 0.8 0.038 13.6 0.5 1.4 1 1 0 1 1 1 0 Triabin DUF2603 PF10788.4 EER29340.1 - 0.047 13.4 7.2 0.084 12.6 2.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2603) GATase_2 PF00310.16 EER29340.1 - 0.08 11.6 1.3 0.14 10.8 0.9 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II DUF2603 PF10788.4 EER29341.1 - 0.0062 16.2 5.2 0.067 12.9 0.4 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF2603) zf-CCHC PF00098.18 EER29341.1 - 0.017 15.0 2.2 0.029 14.2 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle IMD PF08397.6 EER29341.1 - 0.65 9.2 9.3 4.3 6.5 0.1 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain Glyco_transf_90 PF05686.7 EER29342.1 - 6.2e-13 48.1 0.8 6.4e-09 34.9 0.1 3.7 2 1 0 2 2 2 2 Glycosyl transferase family 90 GNAT_acetyltr_2 PF13718.1 EER29343.1 - 6.7e-79 263.7 0.0 1.2e-78 262.9 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EER29343.1 - 5.2e-66 221.6 0.0 1.4e-65 220.2 0.0 1.7 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EER29343.1 - 3e-40 135.8 0.0 7.5e-40 134.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EER29343.1 - 1.5e-36 124.5 0.5 4.1e-36 123.1 0.3 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EER29343.1 - 0.049 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Thioredoxin PF00085.15 EER29344.1 - 2.4e-28 97.8 0.0 1.3e-22 79.4 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EER29344.1 - 1.2e-06 28.7 0.3 3.3e-05 24.0 0.2 2.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EER29344.1 - 7e-05 22.8 0.0 0.0033 17.5 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_6 PF13848.1 EER29344.1 - 8.3e-05 22.4 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EER29344.1 - 0.0057 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EER29344.1 - 0.028 14.4 0.0 0.072 13.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like EutB PF06751.6 EER29344.1 - 0.15 10.3 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) ATP-synt PF00231.14 EER29345.1 - 1.8e-70 237.5 4.3 2.1e-70 237.3 3.0 1.0 1 0 0 1 1 1 1 ATP synthase Ecm33 PF12454.3 EER29345.1 - 1.6 8.6 4.9 1.7 8.5 0.8 2.8 2 1 0 2 2 2 0 GPI-anchored cell wall organization protein Topoisom_I_N PF02919.10 EER29346.1 - 7.4e-97 322.8 1.4 7.4e-97 322.8 1.0 3.0 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EER29346.1 - 1.9e-83 279.1 4.7 1.9e-83 279.1 3.3 2.0 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EER29346.1 - 4.9e-33 112.6 0.6 1.6e-32 110.9 0.4 2.0 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EER29346.1 - 0.03 13.4 0.0 0.073 12.2 0.0 1.6 1 0 0 1 1 1 0 RolB/RolC glucosidase family SQS_PSY PF00494.14 EER29347.1 - 5.8e-15 55.3 0.0 7.7e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Epimerase PF01370.16 EER29348.1 - 5.4e-17 62.0 0.0 7.5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EER29348.1 - 3.5e-10 39.2 0.0 5.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EER29348.1 - 1e-08 34.2 0.0 3.5e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EER29348.1 - 4.9e-05 23.4 0.0 0.00029 20.8 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EER29348.1 - 0.00061 19.7 0.0 0.004 17.0 0.0 2.2 3 0 0 3 3 3 1 short chain dehydrogenase Ldh_1_N PF00056.18 EER29348.1 - 0.013 15.3 0.0 0.065 13.0 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF605 PF04652.11 EER29349.1 - 4.8e-102 342.2 9.6 5.4e-102 342.0 6.7 1.0 1 0 0 1 1 1 1 Vta1 like Mcm10 PF09332.6 EER29349.1 - 0.021 14.2 1.1 0.033 13.5 0.7 1.3 1 0 0 1 1 1 0 Mcm10 replication factor Peptidase_C2 PF00648.16 EER29350.1 - 4e-24 85.1 0.0 6.5e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EER29350.1 - 1.9e-15 56.7 0.0 5.2e-14 52.1 0.0 2.8 2 1 0 2 2 2 1 Calpain large subunit, domain III MIT PF04212.13 EER29350.1 - 3.1e-09 36.5 3.0 5.6e-09 35.7 2.1 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EER29351.1 - 6.5e-56 186.0 0.4 1.1e-21 76.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 EER29351.1 - 1.2 9.5 0.0 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 YtxH-like protein SNase PF00565.12 EER29352.1 - 1.5e-23 83.0 0.0 2.5e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.17 EER29353.1 - 6.9e-34 116.9 0.0 3.5e-31 108.1 0.0 2.1 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EER29353.1 - 1e-14 53.8 0.0 1.9e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EER29353.1 - 0.00053 20.8 0.0 0.0012 19.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EER29353.1 - 0.00059 20.1 0.0 0.0015 18.8 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EER29353.1 - 0.0018 18.1 0.0 0.02 14.7 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EER29353.1 - 0.08 12.8 0.0 0.15 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EER29353.1 - 0.094 11.4 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 EER29353.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_primase_lrg PF04104.9 EER29354.1 - 1.3e-81 273.7 0.0 2.1e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.10 EER29355.1 - 3.3e-79 265.7 0.0 4.8e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EER29355.1 - 2.3e-32 110.4 0.1 4.5e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EER29355.1 - 3.9e-30 104.2 0.0 7.6e-30 103.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EER29355.1 - 5.6e-16 57.8 5.2 1.1e-15 56.8 3.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EER29355.1 - 1.9e-11 43.4 0.0 4.2e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 EER29356.1 - 2e-17 62.3 0.1 3.1e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EER29356.1 - 8.6e-10 38.6 0.1 1.4e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.1 EER29357.1 - 1.1e-102 343.4 0.0 1.8e-54 184.4 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EER29357.1 - 3.1e-25 87.5 10.8 1.3e-09 37.5 0.0 5.3 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.23 EER29357.1 - 1.7e-17 62.2 11.3 0.00024 20.5 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EER29357.1 - 1.2e-14 52.9 12.0 0.045 13.6 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EER29357.1 - 8.2e-14 50.8 4.8 0.0038 17.7 0.1 6.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EER29357.1 - 2.7e-13 50.1 9.2 4.6e-06 27.1 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EER29357.1 - 1.1e-12 47.1 4.6 0.079 13.1 0.0 5.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EER29357.1 - 1.1e-12 47.6 3.6 2.6e-05 24.0 0.2 4.4 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EER29357.1 - 3e-09 37.0 2.5 0.0024 18.1 0.0 3.2 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER29357.1 - 2.5e-08 33.1 2.1 1.3 9.0 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EER29357.1 - 7.9e-08 31.5 1.5 0.0056 16.3 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 EER29357.1 - 8.6e-05 22.7 2.0 1.5 9.4 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EER29357.1 - 0.00015 21.5 15.2 0.15 12.0 0.0 5.7 7 0 0 7 7 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EER29357.1 - 0.0007 19.6 0.1 0.14 12.2 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.12 EER29357.1 - 0.0038 17.5 0.0 4.5 7.5 0.0 2.5 2 0 0 2 2 2 2 Bacterial transcriptional activator domain TPR_9 PF13371.1 EER29357.1 - 0.0069 16.2 3.7 2 8.3 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 EER29357.1 - 0.023 13.7 0.0 2 7.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_5 PF12688.2 EER29357.1 - 0.078 13.0 0.1 0.82 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratrico peptide repeat Myb_DNA-binding PF00249.26 EER29358.1 - 2.5e-24 85.0 1.6 1.6e-12 47.2 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER29358.1 - 2e-20 72.6 2.7 5.8e-15 55.1 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain HTH_38 PF13936.1 EER29358.1 - 0.0039 16.7 0.0 0.0077 15.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DUF2774 PF11242.3 EER29358.1 - 0.0089 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2774) Spc7_N PF15402.1 EER29358.1 - 0.073 11.0 0.7 0.13 10.2 0.5 1.4 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 HTH_23 PF13384.1 EER29358.1 - 0.086 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Myb_DNA-bind_4 PF13837.1 EER29358.1 - 0.095 12.8 1.4 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF2414 PF10309.4 EER29359.1 - 4.8e-24 83.8 0.0 7.5e-24 83.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) Ribosomal_L29e PF01779.12 EER29360.1 - 1.1e-23 82.7 11.5 1.7e-23 82.1 8.0 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.11 EER29361.1 - 2e-18 65.9 0.0 2.7e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cytochrom_B561 PF03188.11 EER29362.1 - 0.00093 19.0 9.6 0.0019 18.0 6.7 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF3180 PF11377.3 EER29362.1 - 0.00095 19.0 0.5 0.00095 19.0 0.3 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3180) DUF2427 PF10348.4 EER29362.1 - 0.77 9.3 5.3 2 8.0 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) PQ-loop PF04193.9 EER29363.1 - 1.2e-34 117.6 15.4 4.4e-18 64.5 0.2 2.8 3 0 0 3 3 3 2 PQ loop repeat zf-C2H2 PF00096.21 EER29364.1 - 6.3e-08 32.5 10.3 0.0035 17.5 0.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER29364.1 - 1.2e-06 28.4 14.0 0.0062 16.7 0.6 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EER29364.1 - 0.015 15.5 11.7 0.073 13.4 0.3 4.1 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.7 EER29364.1 - 0.043 13.9 4.2 0.14 12.3 0.0 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding APH PF01636.18 EER29365.1 - 1.7e-40 139.2 0.0 5.4e-39 134.3 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EER29365.1 - 7.9e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.9 EER29365.1 - 9.7e-05 21.5 0.0 0.00023 20.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EER29365.1 - 0.00044 19.8 0.0 0.00068 19.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EER29365.1 - 0.007 15.7 0.0 0.091 12.1 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Fructosamin_kin PF03881.9 EER29365.1 - 0.029 13.3 0.0 0.38 9.6 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase dUTPase PF00692.14 EER29366.1 - 7.3e-44 148.3 0.0 9.1e-44 148.0 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 EER29366.1 - 0.018 13.4 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.7 EER29367.1 - 3.2e-12 46.1 0.0 1.1e-11 44.4 0.0 1.8 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EER29367.1 - 2.1e-07 30.3 0.9 9.8e-07 28.1 0.2 2.3 2 1 0 2 2 2 1 pfkB family carbohydrate kinase Gluconate_2-dh3 PF13618.1 EER29367.1 - 0.054 13.6 0.2 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DoxD PF04173.8 EER29367.1 - 0.087 12.5 0.0 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 TQO small subunit DoxD Formyl_trans_N PF00551.14 EER29368.1 - 1.2e-38 132.4 0.0 1.4e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase SOG2 PF10428.4 EER29369.1 - 0.015 13.9 2.0 0.02 13.5 1.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIF_alpha PF05793.7 EER29369.1 - 5.9 5.1 5.0 8.1 4.6 3.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Afi1 PF07792.7 EER29370.1 - 6.2e-63 211.1 0.1 1.1e-62 210.3 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EER29370.1 - 5.4e-38 129.1 0.0 8.8e-38 128.4 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EER29370.1 - 1e-08 34.1 0.1 0.0037 15.8 0.0 3.9 3 1 1 4 4 4 3 Transport protein Avl9 DUF72 PF01904.13 EER29370.1 - 0.069 12.8 0.3 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF72 DUF2347 PF09804.4 EER29370.1 - 0.092 12.0 0.0 0.24 10.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Nop14 PF04147.7 EER29370.1 - 4.7 5.0 10.4 7 4.4 7.2 1.2 1 0 0 1 1 1 0 Nop14-like family EF-hand_6 PF13405.1 EER29371.1 - 1.7e-14 52.3 1.3 4.1e-06 26.2 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EER29371.1 - 3.4e-13 47.8 2.2 4.4e-06 25.5 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EER29371.1 - 1.7e-12 47.2 4.2 1.2e-09 38.2 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EER29371.1 - 1.8e-09 36.5 4.8 0.00051 19.2 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EER29371.1 - 3.7e-07 29.6 0.6 0.015 14.9 0.0 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.1 EER29371.1 - 0.14 12.1 0.0 14 5.6 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain ORC6 PF05460.8 EER29371.1 - 4.3 6.3 6.1 6.5 5.7 4.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF605 PF04652.11 EER29371.1 - 8.1 5.7 13.7 11 5.3 9.5 1.1 1 0 0 1 1 1 0 Vta1 like RabGAP-TBC PF00566.13 EER29372.1 - 2.8e-32 111.9 0.1 1.1e-26 93.6 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SET PF00856.23 EER29373.1 - 4e-06 27.2 0.1 0.0043 17.3 0.0 3.4 3 0 0 3 3 3 2 SET domain zf-MYND PF01753.13 EER29373.1 - 0.99 9.3 13.7 0.077 12.8 5.4 2.2 2 0 0 2 2 2 0 MYND finger KCl_Cotrans_1 PF03522.10 EER29373.1 - 2.1 7.9 5.2 14 5.3 3.7 2.4 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) WD40 PF00400.27 EER29374.1 - 4.8e-25 86.4 12.5 2.2e-07 30.5 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat SAPS PF04499.10 EER29374.1 - 0.18 10.3 5.8 0.31 9.6 4.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RRM_1 PF00076.17 EER29376.1 - 4.6e-15 55.0 0.0 6.5e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29376.1 - 1.7e-09 37.4 0.0 2.7e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29376.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EER29376.1 - 0.00097 18.8 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Limkain b1 MIF4G PF02854.14 EER29377.1 - 6.9e-26 90.9 1.0 1.1e-25 90.3 0.2 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EER29377.1 - 1.4e-25 89.1 0.0 5.5e-25 87.2 0.0 2.0 2 0 0 2 2 2 1 MA3 domain Abhydrolase_3 PF07859.8 EER29378.1 - 2.3e-32 112.3 0.0 3.8e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EER29378.1 - 0.00022 20.0 0.0 0.00089 18.0 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Thioesterase PF00975.15 EER29378.1 - 0.016 15.4 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 EER29378.1 - 0.049 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2974 PF11187.3 EER29378.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) WD40 PF00400.27 EER29379.1 - 0.056 13.3 0.1 20 5.2 0.0 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat HD PF01966.17 EER29380.1 - 1.1e-05 25.4 0.2 5e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 HD domain Thr_synth_N PF14821.1 EER29381.1 - 7.6e-26 89.9 0.0 1.7e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EER29381.1 - 6.3e-24 84.7 0.0 6.6e-23 81.3 0.0 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DEAD PF00270.24 EER29383.1 - 1.4e-19 70.1 0.0 4.1e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EER29383.1 - 1.6e-18 67.2 0.0 3.7e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EER29383.1 - 1.2e-17 63.5 0.1 3e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_10 PF12846.2 EER29383.1 - 0.12 11.7 1.3 0.83 9.0 0.0 2.7 2 1 1 3 3 3 0 AAA-like domain F_actin_cap_B PF01115.12 EER29384.1 - 6.9e-100 333.2 0.0 1e-98 329.3 0.0 2.0 2 0 0 2 2 2 2 F-actin capping protein, beta subunit Med11 PF10280.4 EER29385.1 - 1.1e-31 109.2 0.1 1.4e-31 108.9 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein WD40 PF00400.27 EER29386.1 - 6.6e-57 187.4 18.8 2.4e-10 39.8 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EER29386.1 - 1.1e-44 151.9 0.0 1.7e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EER29386.1 - 1.6e-05 24.4 0.1 4.7e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 EER29386.1 - 0.00049 18.3 1.0 0.43 8.6 0.0 3.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EER29386.1 - 0.00085 18.1 0.0 1.9 7.1 0.0 3.8 2 1 2 4 4 4 1 Nup133 N terminal like eIF2A PF08662.6 EER29386.1 - 0.074 12.7 0.1 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Abhydrolase_6 PF12697.2 EER29387.1 - 5.2e-20 72.3 0.1 8e-20 71.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER29387.1 - 2.7e-08 33.6 0.0 4.7e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER29387.1 - 0.00018 21.1 0.0 0.0074 15.8 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EER29387.1 - 0.037 14.2 0.0 1.3 9.2 0.0 2.2 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.20 EER29387.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2417 PF10329.4 EER29388.1 - 2.8e-61 206.8 0.5 4.1e-61 206.3 0.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EER29388.1 - 2.9e-09 37.1 0.1 5.1e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family NfeD PF01957.13 EER29388.1 - 1.6 8.8 8.8 0.15 12.2 1.2 2.2 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding AA_permease_2 PF13520.1 EER29389.1 - 3.7e-46 157.5 43.3 4.8e-46 157.1 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER29389.1 - 8.4e-28 96.9 39.0 1.1e-27 96.5 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease HrcA_DNA-bdg PF03444.10 EER29390.1 - 0.069 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Glyco_hydro_18 PF00704.23 EER29391.1 - 1.2e-74 251.8 2.2 1.8e-74 251.2 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EER29391.1 - 2.1e-09 37.2 12.8 2.1e-09 37.2 8.8 4.1 4 0 0 4 4 4 1 Chitin recognition protein LysM PF01476.15 EER29392.1 - 6.4e-28 96.3 2.1 4.3e-06 26.5 0.0 5.5 5 0 0 5 5 5 5 LysM domain NPL4 PF05021.10 EER29393.1 - 3.6e-130 433.6 0.0 4.4e-130 433.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EER29393.1 - 1.1e-71 239.2 0.0 1.7e-71 238.6 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EER29393.1 - 0.049 13.9 0.0 0.3 11.4 0.0 2.2 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 CVNH PF08881.5 EER29394.1 - 3.7e-23 81.7 0.1 4.1e-23 81.5 0.1 1.0 1 0 0 1 1 1 1 CVNH domain Flavodoxin_1 PF00258.20 EER29395.1 - 6.3e-08 32.7 0.0 1.3e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EER29395.1 - 8.2e-08 31.8 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EER29395.1 - 3.3e-06 26.7 0.0 4.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EER29395.1 - 0.012 15.6 0.0 0.038 13.9 0.0 1.7 1 1 1 2 2 2 0 Flavodoxin domain Flavodoxin_4 PF12682.2 EER29395.1 - 0.08 12.3 0.5 0.65 9.3 0.4 2.1 1 1 0 1 1 1 0 Flavodoxin adh_short PF00106.20 EER29396.1 - 3.8e-18 65.9 0.0 5.4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER29396.1 - 5.5e-06 26.3 0.0 7.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER29396.1 - 5.6e-06 26.1 0.0 8.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EER29396.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EER29396.1 - 0.14 12.1 0.1 0.95 9.4 0.0 2.3 1 1 0 1 1 1 0 NADH(P)-binding 2OG-FeII_Oxy_3 PF13640.1 EER29398.1 - 0.00045 20.6 0.4 0.0011 19.5 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EER29398.1 - 0.0011 19.2 0.0 0.0034 17.6 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PEX11 PF05648.9 EER29399.1 - 4e-26 91.6 0.0 5.3e-26 91.2 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) zf-CCCH PF00642.19 EER29400.1 - 5.5e-16 57.8 28.0 4.4e-06 26.2 0.4 5.3 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EER29400.1 - 0.1 12.0 3.5 2.7 7.5 0.1 3.2 2 0 0 2 2 2 0 Putative zinc-finger domain Glyco_hydro_18 PF00704.23 EER29401.1 - 1.9e-65 221.5 0.0 2.3e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EER29401.1 - 0.00021 21.0 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) DUF3712 PF12505.3 EER29402.1 - 5.5e-34 116.8 1.3 1.5e-33 115.4 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EER29402.1 - 0.02 15.2 0.4 0.082 13.2 0.1 2.0 2 0 0 2 2 2 0 Late embryogenesis abundant protein Sel1 PF08238.7 EER29403.1 - 2.1e-16 59.9 12.9 7.1e-05 23.3 2.6 4.5 4 0 0 4 4 4 4 Sel1 repeat Nucleo_P87 PF07267.6 EER29403.1 - 3.3 6.2 5.4 5.1 5.6 3.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF1776 PF08643.5 EER29405.1 - 5.9e-97 324.3 0.0 7.3e-97 324.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) WLM PF08325.5 EER29406.1 - 2.7e-60 203.4 0.2 6e-60 202.3 0.1 1.6 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EER29406.1 - 0.00021 20.3 1.9 0.00021 20.3 1.3 2.6 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 EER29406.1 - 0.00043 20.1 2.5 0.00086 19.1 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 EER29406.1 - 0.006 16.2 0.1 0.006 16.2 0.0 2.6 2 1 0 2 2 2 1 SprT-like family PIG-H PF10181.4 EER29406.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component DUF955 PF06114.8 EER29406.1 - 0.14 11.8 0.6 0.32 10.7 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF955) DZR PF12773.2 EER29406.1 - 0.28 11.0 12.5 2.6 7.9 8.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon WD40 PF00400.27 EER29407.1 - 3.9e-72 235.7 24.1 9.1e-09 34.8 0.1 11.0 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EER29407.1 - 1.1e-21 76.7 0.0 2.2e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EER29407.1 - 4.7e-06 25.0 2.4 0.022 12.9 0.0 5.1 4 2 0 5 5 5 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EER29407.1 - 0.00031 19.0 0.0 0.061 11.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 EER29407.1 - 0.0044 16.5 0.7 1.4 8.3 0.1 2.8 2 0 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 EER29407.1 - 0.046 12.4 8.5 4.5 5.9 0.2 4.7 2 2 2 6 6 6 0 Nup133 N terminal like P34-Arc PF04045.9 EER29408.1 - 3.1e-101 337.7 0.2 3.8e-101 337.4 0.1 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EER29408.1 - 0.02 14.2 1.0 0.029 13.7 0.1 1.7 2 1 0 2 2 2 0 ARP2/3 complex 20 kDa subunit (ARPC4) Hemerythrin PF01814.18 EER29408.1 - 0.39 10.8 2.3 5.1 7.2 0.3 2.3 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain SpoIIE PF07228.7 EER29410.1 - 1e-05 25.3 0.0 6.3e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EER29410.1 - 1.9e-05 24.1 0.0 0.026 13.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EER29410.1 - 4.7e-05 22.8 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Fcf1 PF04900.7 EER29411.1 - 2.7e-13 49.8 0.7 5.8e-05 23.1 0.1 3.5 2 1 0 2 2 2 2 Fcf1 Cmc1 PF08583.5 EER29412.1 - 9.6e-18 63.7 3.8 1.1e-17 63.5 2.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Bcr-Abl_Oligo PF09036.5 EER29412.1 - 0.16 11.9 1.2 0.19 11.7 0.8 1.1 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain WD40 PF00400.27 EER29413.1 - 1.4e-25 88.1 8.4 1.5e-07 31.0 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 EER29413.1 - 0.00049 18.3 1.3 0.029 12.5 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 RRN3 PF05327.6 EER29415.1 - 5.8e-179 595.8 0.0 8.7e-179 595.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 RecO_C PF02565.10 EER29415.1 - 0.014 15.2 0.0 0.81 9.5 0.0 2.6 2 0 0 2 2 2 0 Recombination protein O C terminal IBN_N PF03810.14 EER29415.1 - 0.035 14.0 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain Abhydrolase_3 PF07859.8 EER29416.1 - 1.8e-44 151.8 0.1 3e-43 147.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EER29416.1 - 1.2e-11 44.1 0.2 2.8e-11 42.8 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EER29416.1 - 0.00065 18.9 0.0 0.2 10.8 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EER29416.1 - 0.0011 18.7 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EER29416.1 - 0.036 12.7 0.0 0.086 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Chlorophyllase2 PF12740.2 EER29416.1 - 0.057 12.2 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Hemerythrin PF01814.18 EER29417.1 - 8.1e-15 55.1 1.6 1.1e-14 54.7 1.1 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Potyvirid-P3 PF13608.1 EER29417.1 - 0.45 9.5 3.3 0.46 9.5 1.3 1.6 2 0 0 2 2 2 0 Protein P3 of Potyviral polyprotein tRNA-synt_2 PF00152.15 EER29418.1 - 2.7e-79 266.3 0.4 3.9e-79 265.8 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EER29418.1 - 2.9e-17 62.4 0.0 4.2e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 EER29418.1 - 0.00022 20.4 0.9 0.44 9.7 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EER29418.1 - 0.00092 19.0 1.5 0.0022 17.7 0.7 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain HSP90 PF00183.13 EER29419.1 - 3.3e-256 850.8 36.9 3.9e-256 850.5 25.6 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EER29419.1 - 3.3e-12 46.2 0.2 3.3e-12 46.2 0.1 2.8 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EER29419.1 - 2.3e-11 43.3 0.0 4.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EER29419.1 - 0.46 10.2 4.4 0.21 11.3 0.1 2.6 3 0 0 3 3 3 0 Tumour suppressor protein Septin PF00735.13 EER29420.1 - 2.4e-10 39.9 0.0 6.3e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 Septin FtsK_SpoIIIE PF01580.13 EER29420.1 - 0.0012 18.3 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EER29420.1 - 0.0019 17.3 0.0 0.0038 16.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Miro PF08477.8 EER29420.1 - 0.002 18.6 0.0 0.005 17.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein T2SE PF00437.15 EER29420.1 - 0.004 16.0 0.2 0.0098 14.8 0.1 1.6 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.1 EER29420.1 - 0.0091 15.4 0.0 0.03 13.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER29420.1 - 0.01 15.7 0.1 0.033 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EER29420.1 - 0.014 15.6 0.8 0.049 13.9 0.0 2.2 2 1 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EER29420.1 - 0.015 14.7 0.3 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain NACHT PF05729.7 EER29420.1 - 0.019 14.6 0.1 0.046 13.3 0.1 1.6 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 EER29420.1 - 0.027 14.4 0.0 0.056 13.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.14 EER29420.1 - 0.044 13.2 0.0 0.097 12.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EER29420.1 - 0.14 11.7 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 HLH PF00010.21 EER29421.1 - 6.5e-14 51.3 0.3 1.3e-13 50.4 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF913 PF06025.7 EER29421.1 - 0.71 8.5 2.9 1.5 7.5 2.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NTF2 PF02136.15 EER29422.1 - 6.3e-23 81.3 0.3 1.1e-22 80.6 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EER29422.1 - 2.2e-07 30.3 0.0 4.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29422.1 - 5.1e-05 23.0 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29422.1 - 7.6e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3534 PF12053.3 EER29422.1 - 0.046 13.5 0.9 0.13 12.1 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) RRM_3 PF08777.6 EER29422.1 - 0.21 11.4 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif ArsC PF03960.10 EER29423.1 - 0.21 11.6 1.2 0.53 10.3 0.9 1.7 1 1 0 1 1 1 0 ArsC family TPR_11 PF13414.1 EER29424.1 - 1e-07 31.4 3.4 0.00077 19.0 0.1 4.4 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 EER29424.1 - 0.00078 19.4 0.6 2.2 8.6 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EER29424.1 - 0.0017 18.8 3.7 35 5.3 0.0 5.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 EER29424.1 - 0.013 15.3 0.6 0.58 10.2 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TipAS PF07739.8 EER29424.1 - 0.038 14.2 0.5 0.16 12.2 0.1 2.2 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain TPR_1 PF00515.23 EER29424.1 - 0.043 13.4 1.3 1 9.1 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EER29424.1 - 0.05 14.2 10.0 1.7 9.4 0.2 4.6 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 EER29424.1 - 0.28 11.5 3.1 98 3.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EER29424.1 - 0.55 10.1 6.0 1.2 9.1 1.2 3.7 4 1 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 EER29425.1 - 2.1e-77 259.8 0.0 2.5e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29425.1 - 2.4e-39 134.9 0.0 3.4e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER29425.1 - 0.00038 19.5 0.2 0.0026 16.7 0.1 2.4 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EER29425.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EER29425.1 - 0.025 13.6 0.2 0.059 12.4 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.12 EER29426.1 - 4.4e-31 107.9 0.0 8.6e-31 107.0 0.0 1.5 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 EER29427.1 - 3.1e-59 200.3 0.9 4.1e-59 199.9 0.6 1.2 1 0 0 1 1 1 1 Cation efflux family DUF111 PF01969.12 EER29427.1 - 0.0035 16.2 0.0 0.0059 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF111 FGGY_C PF02782.11 EER29428.1 - 9.9e-31 106.8 0.0 1.1e-29 103.4 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EER29428.1 - 7.7e-20 71.2 0.0 1.2e-11 44.4 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 EER29429.1 - 3.9e-39 133.9 3.8 6.8e-39 133.1 0.2 3.0 2 1 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 EER29429.1 - 0.002 18.0 0.0 0.79 9.9 0.0 4.5 3 0 0 3 3 3 1 HEAT repeat RIX1 PF08167.7 EER29429.1 - 0.011 15.3 0.4 2.6 7.6 0.0 4.0 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Esterase PF00756.15 EER29430.1 - 2.1e-55 187.9 0.0 2.6e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EER29430.1 - 1e-06 28.5 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EER29430.1 - 2.9e-06 26.7 0.0 7.2e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 EER29430.1 - 9.8e-05 22.3 0.0 0.00015 21.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EER29430.1 - 0.00092 18.1 0.0 0.0019 17.1 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EER29430.1 - 0.0013 17.9 0.1 0.0025 17.0 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 EER29430.1 - 0.0042 16.6 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EER29430.1 - 0.02 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EER29430.1 - 0.048 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.15 EER29430.1 - 0.058 12.9 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_C50 PF03568.12 EER29431.1 - 4.8e-120 400.7 0.0 1.1e-119 399.5 0.0 1.6 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.2 EER29431.1 - 3.3e-05 23.1 0.9 0.0053 15.9 0.0 3.1 2 1 1 3 3 3 2 CHAT domain TPR_2 PF07719.12 EER29431.1 - 0.39 10.7 11.9 34 4.7 0.1 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EER29431.1 - 0.92 9.4 13.0 13 5.7 0.7 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EER29431.1 - 0.95 10.2 7.6 19 6.2 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Muted PF14942.1 EER29432.1 - 0.037 13.9 0.5 0.047 13.5 0.4 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein COG4 PF08318.7 EER29432.1 - 0.038 12.7 0.4 0.046 12.4 0.3 1.0 1 0 0 1 1 1 0 COG4 transport protein DUF1654 PF07867.6 EER29432.1 - 0.36 10.2 3.2 0.51 9.7 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1654) DUF3176 PF11374.3 EER29434.1 - 1.7e-06 27.8 5.2 0.0016 18.3 0.0 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3176) Mito_carr PF00153.22 EER29435.1 - 1.5e-74 245.7 0.6 2.4e-25 88.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_6 PF13405.1 EER29435.1 - 2.6e-15 54.8 0.7 2e-07 30.2 0.1 5.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 EER29435.1 - 1.4e-14 53.9 1.7 1.4e-08 34.7 0.3 4.4 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EER29435.1 - 1.8e-13 48.7 0.2 4.6e-07 28.6 0.0 5.1 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.1 EER29435.1 - 9.5e-09 34.2 1.9 3.4e-05 22.9 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EER29435.1 - 9.3e-08 31.5 5.9 0.15 11.7 0.1 5.4 4 2 2 6 6 6 4 EF-hand domain pair EF-hand_9 PF14658.1 EER29435.1 - 0.01 15.6 0.0 4 7.4 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain Peptidase_M22 PF00814.20 EER29437.1 - 2.9e-50 171.2 0.0 2.5e-47 161.6 0.0 3.3 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.1 EER29437.1 - 0.0036 16.9 0.0 0.0077 15.8 0.0 1.5 1 0 0 1 1 1 1 YycC-like protein DUF726 PF05277.7 EER29438.1 - 0.22 10.3 0.1 0.22 10.3 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF726) Myb_DNA-bind_6 PF13921.1 EER29439.1 - 5.3e-11 42.4 1.2 6.4e-10 38.9 0.3 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER29439.1 - 4.8e-05 23.3 0.2 0.00074 19.5 0.0 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain Rap1_C PF11626.3 EER29439.1 - 0.04 13.7 0.0 0.07 13.0 0.0 1.4 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Phi-29_GP3 PF05435.6 EER29439.1 - 0.088 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 zf-HC5HC2H_2 PF13832.1 EER29441.1 - 1e-32 112.4 3.2 1e-32 112.4 2.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EER29441.1 - 1.3e-27 95.7 0.9 1.3e-27 95.7 0.6 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EER29441.1 - 7.2e-25 88.0 0.0 1.5e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like PHD_2 PF13831.1 EER29441.1 - 7.1e-14 50.8 3.6 7.1e-14 50.8 2.5 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EER29441.1 - 2.2e-08 33.6 24.4 6.2e-08 32.2 7.0 2.6 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 EER29441.1 - 7.1 6.7 20.9 0.11 12.4 4.2 2.6 2 1 0 2 2 2 0 RING-like domain CAP_N PF01213.14 EER29441.1 - 8.5 5.5 8.3 28 3.8 5.7 1.9 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RRM_1 PF00076.17 EER29442.1 - 1.4e-20 72.6 0.0 2.2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29442.1 - 1.2e-15 57.1 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29442.1 - 9.1e-11 41.4 0.0 1.4e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy-30 PF05186.8 EER29443.1 - 8.2e-13 47.6 0.8 1.4e-12 46.9 0.5 1.3 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.6 EER29444.1 - 2.5e-18 65.9 0.1 1.4e-17 63.4 0.0 2.2 2 0 0 2 2 2 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 EER29445.1 - 3.6e-30 103.5 0.1 7e-30 102.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EER29445.1 - 1.1e-22 79.5 0.1 1.9e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EER29445.1 - 0.022 14.4 0.1 0.049 13.3 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain Chromate_transp PF02417.10 EER29446.1 - 2.1e-51 173.8 23.3 6.2e-27 94.2 7.2 2.1 2 0 0 2 2 2 2 Chromate transporter CcmH PF03918.9 EER29446.1 - 0.19 10.7 0.8 0.53 9.2 0.0 2.1 3 0 0 3 3 3 0 Cytochrome C biogenesis protein DUF3129 PF11327.3 EER29447.1 - 7.3e-61 205.1 12.7 9.4e-60 201.5 8.8 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) ketoacyl-synt PF00109.21 EER29448.1 - 7.7e-75 251.6 0.2 1.8e-74 250.4 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EER29448.1 - 6.6e-32 109.8 0.0 1.8e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EER29448.1 - 1.2e-25 90.5 0.0 2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 EER29448.1 - 1.4e-21 76.5 3.8 4.9e-11 42.7 0.2 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Abhydrolase_3 PF07859.8 EER29448.1 - 2.2e-15 56.7 0.0 7.8e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Methyltransf_12 PF08242.7 EER29448.1 - 4.3e-15 56.0 0.0 1e-14 54.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER29448.1 - 1.7e-11 44.1 0.0 5.5e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER29448.1 - 8e-10 38.9 0.0 2.1e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 EER29448.1 - 9.6e-10 38.0 0.0 1.7e-05 24.1 0.0 3.1 3 0 0 3 3 3 2 Prolyl oligopeptidase family Methyltransf_31 PF13847.1 EER29448.1 - 1.6e-09 37.4 0.0 5.7e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Abhydrolase_5 PF12695.2 EER29448.1 - 3.2e-09 36.6 0.0 1e-07 31.7 0.0 2.9 3 0 0 3 3 3 1 Alpha/beta hydrolase family Methyltransf_11 PF08241.7 EER29448.1 - 1.1e-07 32.1 0.0 3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER29448.1 - 2.6e-06 27.9 0.0 1.9e-05 25.1 0.0 2.6 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER29448.1 - 1.3e-05 25.1 0.0 3.7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EER29448.1 - 1.6e-05 24.9 0.7 5.5e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ubie_methyltran PF01209.13 EER29448.1 - 3.6e-05 23.0 0.0 8e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DLH PF01738.13 EER29448.1 - 0.00061 19.1 0.0 0.074 12.3 0.0 2.5 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EER29448.1 - 0.0021 17.5 0.0 1.3 8.3 0.0 2.5 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Thiolase_N PF00108.18 EER29448.1 - 0.0031 16.5 0.0 0.0061 15.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 EER29448.1 - 0.02 13.9 0.0 0.057 12.4 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase COesterase PF00135.23 EER29448.1 - 0.024 13.3 0.0 0.085 11.5 0.0 1.8 2 1 0 2 2 2 0 Carboxylesterase family Abhydrolase_1 PF00561.15 EER29448.1 - 0.083 12.4 0.2 4.6 6.7 0.0 2.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Methyltransf_16 PF10294.4 EER29448.1 - 0.15 11.5 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase AXE1 PF05448.7 EER29448.1 - 0.16 10.4 0.0 0.3 9.5 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1033 PF06279.6 EER29448.1 - 0.8 9.5 2.8 0.86 9.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) AMP-binding PF00501.23 EER29449.1 - 1.4e-29 102.7 0.0 4.9e-29 100.9 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EER29449.1 - 7.7e-28 97.0 0.0 1.1e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EER29449.1 - 6.3e-06 25.7 0.0 3.6e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EER29449.1 - 9.6e-05 22.5 0.1 0.00039 20.6 0.1 2.2 1 1 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EER29449.1 - 0.0031 17.4 0.0 0.048 13.5 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EER29449.1 - 0.046 13.3 0.0 0.2 11.3 0.0 2.1 1 0 0 1 1 1 0 KR domain Myb_DNA-binding PF00249.26 EER29450.1 - 7.3e-27 93.1 7.5 9.2e-08 32.0 0.0 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER29450.1 - 3.2e-26 91.2 0.6 3.9e-11 42.8 0.0 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EER29450.1 - 0.00011 22.0 5.7 0.31 10.9 2.2 3.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.4 EER29450.1 - 0.012 15.7 1.3 0.076 13.2 0.1 2.3 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SLIDE PF09111.5 EER29450.1 - 0.1 12.3 0.0 1.7 8.3 0.0 2.7 2 1 1 3 3 3 0 SLIDE adh_short PF00106.20 EER29451.1 - 6.7e-26 91.1 0.3 9.1e-26 90.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER29451.1 - 6.2e-08 32.5 0.1 9.3e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EER29451.1 - 0.00064 19.4 2.1 0.0009 18.9 0.9 1.7 1 1 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_4 PF01565.18 EER29452.1 - 1.6e-21 76.2 0.7 1.6e-21 76.2 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EER29452.1 - 0.014 15.2 0.1 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Methyltransf_2 PF00891.13 EER29453.1 - 2.4e-25 89.1 0.0 3.5e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Phage_rep_org_N PF09681.5 EER29453.1 - 0.028 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Aldo_ket_red PF00248.16 EER29454.1 - 7.6e-50 169.3 0.0 8.6e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATP-synt_F PF01990.12 EER29454.1 - 0.12 12.7 0.0 22 5.5 0.0 3.2 3 0 0 3 3 3 0 ATP synthase (F/14-kDa) subunit Methyltransf_2 PF00891.13 EER29455.1 - 1.9e-25 89.4 0.0 5.8e-25 87.8 0.0 1.8 2 1 0 2 2 2 1 O-methyltransferase DUF1857 PF08982.6 EER29456.1 - 1.1e-29 102.9 0.1 7.9e-29 100.1 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1857) p450 PF00067.17 EER29457.1 - 7e-69 232.5 0.0 9.1e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 INCENP_ARK-bind PF03941.10 EER29458.1 - 0.12 12.2 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region FA_hydroxylase PF04116.8 EER29459.1 - 2e-15 57.1 16.0 4.7e-15 55.9 11.1 1.6 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily 7tm_2 PF00002.19 EER29460.1 - 6.6e-07 28.6 10.7 1.3e-06 27.7 3.9 2.2 1 1 0 2 2 2 2 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EER29460.1 - 8.6e-05 21.5 1.2 8.6e-05 21.5 0.8 1.9 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor MRAP PF15183.1 EER29460.1 - 3.5 7.3 5.4 4.5 6.9 0.4 3.1 3 1 0 3 3 3 0 Melanocortin-2 receptor accessory protein family RRM_1 PF00076.17 EER29461.1 - 2e-29 100.9 0.3 1.3e-13 50.3 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29461.1 - 1.8e-18 66.3 0.0 1.1e-05 25.3 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29461.1 - 3.8e-16 58.6 0.0 1.9e-06 27.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OGG_N PF07934.7 EER29462.1 - 4.2e-38 129.9 0.2 8.2e-38 128.9 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EER29462.1 - 1.6e-13 50.8 0.0 2.7e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2256 PF10013.4 EER29462.1 - 0.014 15.1 0.7 0.044 13.5 0.5 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) HHH PF00633.18 EER29462.1 - 0.019 14.6 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2491 PF10679.4 EER29462.1 - 0.058 12.3 0.0 0.17 10.8 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2491) SET PF00856.23 EER29463.1 - 3.4e-10 40.4 0.0 4.1e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 SET domain DUF2688 PF10892.3 EER29463.1 - 0.0021 17.6 0.2 0.0042 16.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2688) Phe_tRNA-synt_N PF02912.13 EER29463.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Pkinase PF00069.20 EER29464.1 - 1.8e-14 53.5 0.0 4.4e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29464.1 - 0.0002 20.5 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER29465.1 - 1.2e-11 44.8 0.0 3.6e-11 43.2 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF965 PF06135.7 EER29467.1 - 2.1e-05 24.4 3.9 0.54 10.3 0.0 4.2 2 2 2 4 4 4 2 Bacterial protein of unknown function (DUF965) LNS2 PF08235.8 EER29467.1 - 0.0027 17.2 0.7 0.035 13.6 0.0 2.8 3 2 0 3 3 3 1 LNS2 (Lipin/Ned1/Smp2) Glyoxalase_4 PF13669.1 EER29467.1 - 0.0066 16.4 0.1 6.1 6.9 0.0 4.1 4 1 1 5 5 5 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1018 PF06252.7 EER29467.1 - 0.027 14.9 0.0 1.6 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) DUF3936 PF13072.1 EER29467.1 - 0.037 13.4 0.2 37 3.8 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3936) Hydrolase_4 PF12146.3 EER29467.1 - 0.044 13.6 0.7 8.4 6.3 0.0 3.5 5 0 0 5 5 5 0 Putative lysophospholipase DUF4113 PF13438.1 EER29467.1 - 0.13 11.9 5.2 4.3 7.0 0.0 4.1 5 0 0 5 5 5 0 Domain of unknown function (DUF4113) Barwin PF00967.12 EER29467.1 - 2.7 7.7 7.0 1.6 8.4 0.2 3.1 2 1 1 4 4 4 0 Barwin family DEAD PF00270.24 EER29468.1 - 2.2e-18 66.3 0.0 4.5e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EER29468.1 - 1.6e-07 31.3 0.0 1.1e-06 28.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EER29468.1 - 8.4e-07 28.7 0.1 2e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IL4Ra_N PF09238.5 EER29468.1 - 0.035 14.2 0.1 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 Interleukin-4 receptor alpha chain, N-terminal PhoH PF02562.11 EER29468.1 - 0.083 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Acetyltransf_1 PF00583.19 EER29469.1 - 4.6e-16 58.6 0.1 6.8e-16 58.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EER29469.1 - 1.8e-10 40.3 0.0 3.6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EER29469.1 - 2.3e-09 37.3 0.0 3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER29469.1 - 2e-08 34.2 0.1 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EER29469.1 - 5.2e-07 29.9 0.0 6.6e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER29469.1 - 0.00016 21.5 0.0 0.00052 19.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EER29469.1 - 0.0002 21.1 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EER29469.1 - 0.0014 18.1 0.0 0.0024 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPR_15 PF13429.1 EER29469.1 - 0.0037 16.3 0.1 0.0043 16.1 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat E1-E2_ATPase PF00122.15 EER29470.1 - 1e-48 165.3 0.1 1e-48 165.3 0.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EER29470.1 - 2.4e-16 60.7 0.0 4.4e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EER29470.1 - 1.7e-15 57.7 0.0 3.5e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EER29470.1 - 5.5e-15 55.3 5.0 5.5e-15 55.3 3.5 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EER29470.1 - 5e-14 51.5 1.2 9.4e-14 50.6 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EER29470.1 - 1.4e-06 28.1 0.0 3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Fungal_trans_2 PF11951.3 EER29471.1 - 1.2e-08 33.9 0.3 4.9e-08 31.9 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rax2 PF12768.2 EER29472.1 - 1.9e-98 329.1 0.0 1.7e-90 303.0 0.0 4.4 4 0 0 4 4 4 3 Cortical protein marker for cell polarity Kelch_4 PF13418.1 EER29472.1 - 0.45 10.3 4.7 2 8.2 0.1 4.6 5 0 0 5 5 5 0 Galactose oxidase, central domain Gp5_C PF06715.7 EER29472.1 - 1.3 9.1 4.5 13 5.9 0.1 4.4 4 0 0 4 4 4 0 Gp5 C-terminal repeat (3 copies) SSrecog PF03531.9 EER29473.1 - 3.2e-71 239.1 1.3 4.8e-70 235.3 0.9 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EER29473.1 - 5.3e-26 90.4 0.1 4.6e-25 87.4 0.0 2.3 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SAP PF02037.22 EER29474.1 - 2.6e-11 42.7 0.0 5.5e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 SAP domain DUF3455 PF11937.3 EER29476.1 - 8e-35 120.3 0.0 9.6e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SF3b1 PF08920.5 EER29477.1 - 7.8e-45 152.4 12.9 2e-43 147.9 1.3 2.4 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EER29477.1 - 5.3e-15 55.4 3.8 0.011 16.0 0.0 7.3 6 2 2 8 8 8 5 HEAT repeats HEAT PF02985.17 EER29477.1 - 2.6e-11 42.6 8.7 1 9.6 0.0 9.2 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 EER29477.1 - 4.4e-10 39.7 4.4 0.54 10.8 0.0 7.8 6 2 2 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EER29477.1 - 1.2e-05 25.6 0.3 0.95 9.8 0.0 5.6 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EER29477.1 - 0.0011 17.4 0.1 0.39 8.9 0.0 3.1 3 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 EER29477.1 - 0.0062 15.9 0.6 4.6 6.5 0.0 3.9 4 0 0 4 4 4 1 NUC173 domain Cnd1 PF12717.2 EER29477.1 - 0.0067 16.2 0.1 13 5.5 0.0 4.4 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EER29477.1 - 0.021 14.2 0.4 1 8.6 0.0 3.4 4 0 0 4 4 4 0 CLASP N terminal CRM1_C PF08767.6 EER29477.1 - 0.091 11.6 0.5 0.48 9.2 0.1 2.4 3 0 0 3 3 3 0 CRM1 C terminal DUF2890 PF11081.3 EER29477.1 - 8.3 6.4 17.6 1.8e+02 2.0 11.8 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) MFS_1 PF07690.11 EER29478.1 - 4.4e-37 127.6 34.2 4.4e-37 127.6 23.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EER29479.1 - 1.6e-27 96.0 1.0 2.5e-27 95.3 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29479.1 - 5.4e-09 35.8 11.8 1e-08 34.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 EER29480.1 - 2e-32 112.8 0.0 2.5e-32 112.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EER29480.1 - 4.4e-29 101.5 0.8 5.6e-29 101.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER29480.1 - 3.9e-12 46.2 0.1 5.7e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EER29480.1 - 0.0077 15.9 1.0 0.015 15.0 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3127 PF11325.3 EER29480.1 - 0.063 13.2 0.1 2.6 8.1 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3127) 3HCDH_N PF02737.13 EER29480.1 - 0.076 12.6 1.7 0.19 11.3 0.9 1.7 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EER29480.1 - 0.076 12.4 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_2 PF00890.19 EER29481.1 - 3.3e-44 151.4 0.6 1.3e-43 149.3 0.4 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EER29481.1 - 6.1e-12 45.1 0.7 1.3e-11 44.0 0.5 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EER29481.1 - 1.2e-09 37.8 4.4 5.3e-09 35.6 1.7 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EER29481.1 - 4.1e-06 25.5 3.9 0.019 13.4 0.1 3.3 3 0 0 3 3 3 3 HI0933-like protein Pyr_redox_3 PF13738.1 EER29481.1 - 4.2e-05 23.7 0.4 0.086 12.8 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EER29481.1 - 8.5e-05 22.5 2.2 0.015 15.1 0.9 3.0 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EER29481.1 - 0.00025 20.2 0.1 0.075 12.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EER29481.1 - 0.023 13.8 0.2 0.05 12.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EER29481.1 - 0.038 13.5 0.1 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EER29481.1 - 0.047 12.5 0.3 0.047 12.5 0.2 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A GMC_oxred_N PF00732.14 EER29481.1 - 0.059 12.5 0.1 0.78 8.8 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Lycopene_cycl PF05834.7 EER29481.1 - 0.13 11.1 0.1 0.24 10.2 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein Aldedh PF00171.17 EER29482.1 - 1.3e-146 488.5 0.0 1.5e-146 488.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TGS PF02824.16 EER29482.1 - 0.01 15.6 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 0 TGS domain LuxC PF05893.9 EER29482.1 - 0.014 14.1 0.2 0.075 11.7 0.1 1.9 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Lactamase_B PF00753.22 EER29483.1 - 9e-07 28.7 2.1 4.7e-06 26.3 1.4 2.0 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EER29483.1 - 1.5e-06 27.9 0.1 2.4e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EER29483.1 - 0.082 12.6 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_L7Ae PF01248.21 EER29484.1 - 1.8e-24 85.0 0.0 2.4e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2 PF00096.21 EER29485.1 - 2.1e-10 40.3 11.4 2e-05 24.6 3.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER29485.1 - 2.5e-10 40.0 15.0 9.2e-06 25.7 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER29485.1 - 1.5e-07 31.1 8.7 0.00021 21.4 1.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EER29485.1 - 2e-05 24.6 1.5 2e-05 24.6 1.0 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EER29485.1 - 0.00012 22.0 2.1 0.00012 22.0 1.4 3.3 4 0 0 4 4 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EER29485.1 - 0.00026 20.7 6.9 0.0041 16.9 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EER29485.1 - 0.59 9.8 3.8 6.1 6.6 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Med3 PF11593.3 EER29485.1 - 1.4 8.0 8.5 0.14 11.3 1.0 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal BAF1_ABF1 PF04684.8 EER29485.1 - 1.7 7.4 9.9 2.5 6.8 6.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-BED PF02892.10 EER29485.1 - 1.7 8.4 6.4 12 5.7 4.5 2.2 1 1 0 1 1 1 0 BED zinc finger PAT1 PF09770.4 EER29485.1 - 5.3 5.1 16.8 8.2 4.5 11.6 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 EER29486.1 - 1.1e-12 47.3 0.5 1.8e-12 46.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNARE PF05739.14 EER29487.1 - 0.0016 18.1 2.8 0.0016 18.1 2.0 2.9 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 EER29487.1 - 0.061 13.4 3.9 0.17 11.9 0.5 2.7 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Sec1 PF00995.18 EER29488.1 - 9.4e-127 424.0 0.0 1.1e-126 423.8 0.0 1.0 1 0 0 1 1 1 1 Sec1 family HTH_27 PF13463.1 EER29488.1 - 0.083 13.2 0.0 5.6 7.3 0.0 3.3 3 0 0 3 3 3 0 Winged helix DNA-binding domain Telomere_reg-2 PF10193.4 EER29489.1 - 2.4e-32 111.5 0.0 5.8e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.16 EER29490.1 - 2.4e-39 134.2 0.1 5.7e-39 133.0 0.0 1.6 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EER29490.1 - 3.2e-29 100.5 0.0 5.6e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EER29490.1 - 5.1e-25 86.8 0.3 9.9e-25 85.9 0.2 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EER29490.1 - 1.1e-14 53.4 2.9 1.1e-14 53.4 2.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EER29490.1 - 0.00018 21.6 0.0 0.00036 20.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EER29490.1 - 0.00029 20.3 0.0 0.00054 19.5 0.0 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EER29490.1 - 0.024 14.7 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 EER29490.1 - 0.046 13.6 2.3 0.094 12.6 1.6 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein UAE_UbL PF14732.1 EER29490.1 - 0.06 13.4 0.1 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Pyr_redox PF00070.22 EER29490.1 - 0.093 13.1 0.1 0.32 11.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_A_bac PF01000.21 EER29491.1 - 1.2e-25 89.8 0.0 2.7e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EER29491.1 - 4.5e-12 44.9 0.0 6.7e-12 44.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 EER29492.1 - 4.9e-135 448.8 0.0 6.3e-135 448.4 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit UQ_con PF00179.21 EER29493.1 - 1e-24 86.5 0.1 1.3e-24 86.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EER29493.1 - 1.3e-05 24.9 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EER29493.1 - 9.6e-05 22.2 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 RWD domain Pkinase PF00069.20 EER29494.1 - 1e-70 237.8 0.0 1.5e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29494.1 - 3.3e-34 118.1 0.1 5.6e-34 117.3 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EER29494.1 - 1.3e-05 24.2 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EER29494.1 - 0.00096 18.5 0.0 0.0028 17.0 0.0 1.8 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EER29494.1 - 0.016 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EER29494.1 - 0.042 13.5 0.1 0.27 10.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EER29496.1 - 1.1e-55 188.6 0.0 1.5e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29496.1 - 1e-40 139.4 0.0 1.5e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER29496.1 - 2.1e-05 23.6 0.0 3.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EER29496.1 - 0.0092 15.7 0.0 0.026 14.2 0.0 1.8 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EER29496.1 - 0.023 13.7 0.1 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EER29496.1 - 0.033 13.5 0.4 0.16 11.2 0.3 1.9 1 1 0 1 1 1 0 RIO1 family Aminotran_1_2 PF00155.16 EER29497.1 - 1.4e-17 63.7 0.0 1.7e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CbiA PF01656.18 EER29497.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fungal_trans PF04082.13 EER29498.1 - 6.6e-21 74.3 0.0 1.4e-20 73.2 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29498.1 - 3.6e-09 36.3 11.6 5.9e-09 35.6 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_26 PF13659.1 EER29498.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain G-alpha PF00503.15 EER29498.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Prefoldin_2 PF01920.15 EER29499.1 - 4.8e-24 84.1 8.8 5.6e-24 83.9 6.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EER29499.1 - 0.007 15.9 6.3 0.055 13.1 0.2 2.2 1 1 2 3 3 3 1 Prefoldin subunit V_ATPase_I PF01496.14 EER29499.1 - 0.0084 14.0 1.4 0.01 13.7 0.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2089 PF09862.4 EER29499.1 - 0.015 15.0 1.3 0.074 12.8 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2089) p25-alpha PF05517.7 EER29499.1 - 0.023 14.9 1.0 0.29 11.3 0.1 2.0 2 0 0 2 2 2 0 p25-alpha DASH_Dad3 PF08656.5 EER29499.1 - 0.035 13.7 3.4 0.064 12.9 0.6 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF641 PF04859.7 EER29499.1 - 0.047 13.4 2.4 0.071 12.8 0.2 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) GAS PF13851.1 EER29499.1 - 0.13 11.4 7.1 0.22 10.7 4.9 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tho2 PF11262.3 EER29499.1 - 0.14 11.1 2.9 6.4 5.7 0.0 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Syntaxin-6_N PF09177.6 EER29499.1 - 0.17 12.2 2.2 0.75 10.2 0.5 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PMC2NT PF08066.7 EER29499.1 - 0.21 11.8 1.6 1.5 9.2 0.1 2.0 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Piwi PF02171.12 EER29499.1 - 0.29 10.0 2.3 2.8 6.8 1.6 2.0 1 1 0 1 1 1 0 Piwi domain IncA PF04156.9 EER29499.1 - 0.39 10.3 8.5 1 8.9 5.8 1.6 1 1 0 1 1 1 0 IncA protein DASH_Dad2 PF08654.5 EER29499.1 - 0.44 10.5 4.1 4.1 7.4 0.7 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 Fib_alpha PF08702.5 EER29499.1 - 1 9.4 5.8 1.7 8.7 4.0 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.4 EER29499.1 - 1.2 8.7 6.2 0.2 11.2 0.7 2.0 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF904 PF06005.7 EER29499.1 - 1.5 9.1 8.4 6.5 7.1 1.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_Maf PF03131.12 EER29499.1 - 2.4 8.5 5.9 12 6.2 1.6 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor CBFD_NFYB_HMF PF00808.18 EER29500.1 - 1.5e-28 98.5 0.5 2.2e-28 98.1 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EER29500.1 - 3.8e-06 26.9 0.0 5.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EER29500.1 - 0.0024 17.5 0.1 0.0044 16.7 0.0 1.5 1 1 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 EER29500.1 - 0.0051 16.5 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 EER29500.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF466 PF04328.8 EER29500.1 - 0.65 9.8 3.7 0.3 10.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF466) HA2 PF04408.18 EER29501.1 - 2.6e-25 88.3 0.0 1e-24 86.4 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EER29501.1 - 3.2e-24 84.9 0.0 1.9e-22 79.2 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EER29501.1 - 2.7e-14 52.7 0.0 7.1e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EER29501.1 - 5.3e-07 29.2 0.1 1.4e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EER29501.1 - 0.00028 21.0 0.0 0.00058 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EER29501.1 - 0.00054 18.9 0.0 0.0039 16.1 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.10 EER29501.1 - 0.0021 17.8 0.0 0.76 9.5 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EER29501.1 - 0.012 15.5 0.1 0.063 13.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EER29501.1 - 0.015 14.3 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EER29501.1 - 0.017 14.7 1.3 0.55 9.8 0.1 2.9 3 0 0 3 3 3 0 NACHT domain SRP54 PF00448.17 EER29501.1 - 0.026 13.9 0.3 0.067 12.6 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EER29501.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain KaiC PF06745.8 EER29501.1 - 0.035 13.2 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 EER29501.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.1 EER29501.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EER29501.1 - 0.22 11.7 0.3 0.71 10.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain DAD PF02109.11 EER29502.1 - 2.7e-40 136.9 3.1 5.9e-39 132.6 2.2 2.0 1 1 0 1 1 1 1 DAD family DUF3446 PF11928.3 EER29502.1 - 2.2 8.5 8.3 15 5.8 2.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Tmemb_14 PF03647.8 EER29503.1 - 1.5e-23 82.9 8.6 1.8e-23 82.7 6.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Abhydrolase_6 PF12697.2 EER29503.1 - 0.069 13.0 0.4 0.076 12.8 0.3 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family RTC4 PF14474.1 EER29504.1 - 1.1e-37 128.7 0.0 1.7e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain DUF726 PF05277.7 EER29505.1 - 9.3e-128 425.9 1.7 1.3e-127 425.4 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF3145 PF11343.3 EER29505.1 - 0.0032 16.8 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3145) Lipase_3 PF01764.20 EER29505.1 - 0.16 11.5 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Pyr_redox_3 PF13738.1 EER29506.1 - 6.2e-23 81.9 0.0 8.8e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EER29506.1 - 9.4e-16 57.0 0.1 3.3e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EER29506.1 - 2.8e-12 46.4 0.0 1.8e-08 34.2 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EER29506.1 - 5.9e-07 28.7 0.0 6.1e-06 25.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EER29506.1 - 7.5e-07 29.2 0.0 0.0024 17.7 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EER29506.1 - 3.5e-05 22.8 1.2 0.0078 15.1 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EER29506.1 - 0.00014 21.0 0.3 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 EER29506.1 - 0.00015 20.9 0.1 0.0018 17.4 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EER29506.1 - 0.00027 21.2 0.2 0.74 10.2 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER29506.1 - 0.00081 19.1 0.2 0.041 13.6 0.0 3.2 3 2 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.17 EER29506.1 - 0.0091 14.8 0.0 6 5.6 0.0 3.2 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EER29506.1 - 0.011 14.5 0.0 0.44 9.3 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EER29506.1 - 0.016 13.6 0.8 2.2 6.6 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_2 PF03446.10 EER29506.1 - 0.018 14.8 0.1 0.17 11.7 0.0 2.3 3 0 0 3 3 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EER29506.1 - 0.025 14.6 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 EER29506.1 - 0.027 13.4 0.3 3.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EER29506.1 - 0.068 12.8 0.0 0.52 9.9 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EER29506.1 - 0.35 10.7 0.8 16 5.3 0.0 2.4 2 0 0 2 2 2 0 ThiF family APH PF01636.18 EER29507.1 - 3.6e-29 102.1 0.9 4.7e-29 101.8 0.6 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EER29507.1 - 0.00043 19.6 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family LicD PF04991.8 EER29508.1 - 4.1e-36 125.0 4.2 2.4e-35 122.5 2.9 2.0 1 1 0 1 1 1 1 LicD family Fungal_trans PF04082.13 EER29509.1 - 1.2e-18 66.9 0.2 2.8e-18 65.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29509.1 - 5.7e-09 35.7 12.3 1.1e-08 34.8 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EER29510.1 - 1.4e-31 109.5 50.2 6.5e-30 104.0 13.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER29510.1 - 3.6e-12 45.6 1.8 3.6e-12 45.6 1.3 3.1 2 1 2 4 4 4 1 Sugar (and other) transporter MFS_2 PF13347.1 EER29510.1 - 3.1e-05 22.5 2.5 3.1e-05 22.5 1.7 2.3 2 0 0 2 2 2 1 MFS/sugar transport protein ATG22 PF11700.3 EER29510.1 - 0.00011 20.7 2.4 0.00011 20.7 1.7 2.8 2 2 0 2 2 2 1 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EER29510.1 - 0.0041 16.8 2.3 0.0061 16.3 0.1 2.6 2 0 0 2 2 2 1 MFS_1 like family TRI12 PF06609.8 EER29510.1 - 0.0042 15.3 0.3 0.0042 15.3 0.2 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2754 PF10953.3 EER29510.1 - 2.8 8.0 7.6 0.35 10.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2754) TFR_dimer PF04253.10 EER29511.1 - 5.4e-21 74.4 0.0 9e-21 73.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EER29511.1 - 1.2e-15 57.6 0.0 3.1e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EER29511.1 - 3.7e-05 23.3 0.1 0.0001 21.9 0.0 1.8 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 EER29511.1 - 0.0016 17.7 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 Nicastrin zf-C2H2_4 PF13894.1 EER29512.1 - 0.034 14.4 6.5 0.077 13.3 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EER29512.1 - 0.044 14.1 0.1 0.044 14.1 0.1 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-Di19 PF05605.7 EER29512.1 - 0.14 12.3 0.6 3.9 7.6 0.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PAT1 PF09770.4 EER29512.1 - 0.21 9.7 38.8 0.3 9.2 26.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_jaz PF12171.3 EER29512.1 - 1.4 9.1 5.1 12 6.1 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EER29512.1 - 8.4 6.4 7.8 6.6 6.7 0.0 2.8 2 1 1 3 3 3 0 C2H2-type zinc finger CMD PF02627.15 EER29514.1 - 1.8e-07 30.8 0.1 6.4e-05 22.7 0.0 2.4 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family DUF2413 PF10310.4 EER29515.1 - 1.6e-141 472.1 0.0 1.9e-141 471.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) DUF605 PF04652.11 EER29515.1 - 3.4 6.9 11.6 6.1 6.1 8.1 1.3 1 0 0 1 1 1 0 Vta1 like Zn_clus PF00172.13 EER29516.1 - 0.00014 21.7 4.6 0.00033 20.4 3.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GAS PF13851.1 EER29517.1 - 0.00089 18.5 4.9 0.0015 17.7 3.4 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4135 PF13575.1 EER29517.1 - 0.037 13.0 0.6 0.066 12.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) APG6 PF04111.7 EER29517.1 - 1.1 8.2 8.1 1.9 7.4 5.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Macoilin PF09726.4 EER29517.1 - 3.9 5.6 17.0 0.04 12.2 6.4 1.5 2 0 0 2 2 2 0 Transmembrane protein V_ATPase_I PF01496.14 EER29517.1 - 3.9 5.2 3.3 5.5 4.7 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tropomyosin_1 PF12718.2 EER29517.1 - 4.3 7.1 14.0 5.5 6.8 8.3 2.1 1 1 1 2 2 2 0 Tropomyosin like HNH_2 PF13391.1 EER29518.1 - 1.5e-13 50.2 1.3 1.5e-13 50.2 0.9 3.2 4 1 0 4 4 4 1 HNH endonuclease GPI-anchored PF10342.4 EER29519.1 - 3.2e-22 78.8 0.8 3.2e-22 78.8 0.6 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family fn3 PF00041.16 EER29519.1 - 0.076 13.1 0.7 0.28 11.3 0.2 2.0 2 0 0 2 2 2 0 Fibronectin type III domain Aldedh PF00171.17 EER29520.1 - 4.3e-134 447.3 0.1 5.2e-134 447.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IBN_N PF03810.14 EER29521.1 - 3.7e-13 49.1 0.0 1.6e-11 43.9 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EER29521.1 - 0.00011 22.1 3.1 0.013 15.4 0.0 3.1 3 0 0 3 3 3 2 Exportin 1-like protein Pex2_Pex12 PF04757.9 EER29522.1 - 4.6e-43 147.2 0.4 8e-43 146.4 0.3 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EER29522.1 - 0.00016 21.4 4.7 0.00033 20.4 3.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EER29522.1 - 0.033 13.8 0.8 0.078 12.6 0.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EER29522.1 - 0.035 13.8 0.2 0.035 13.8 0.1 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EER29522.1 - 0.15 12.1 8.6 0.063 13.3 3.0 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER29522.1 - 1.1 9.1 7.1 10 6.0 2.2 2.5 2 1 0 2 2 2 0 Ring finger domain DUF1772 PF08592.6 EER29523.1 - 4.9e-20 71.6 4.3 1.1e-19 70.5 2.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) ILVD_EDD PF00920.16 EER29524.1 - 1.5e-202 673.7 2.7 1.7e-202 673.5 1.8 1.0 1 0 0 1 1 1 1 Dehydratase family InvH PF04741.7 EER29524.1 - 0.22 11.3 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein Abhydrolase_6 PF12697.2 EER29525.1 - 2e-20 73.6 0.0 4.3e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER29525.1 - 1.1e-13 51.2 0.0 5.9e-13 48.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 EER29525.1 - 1.6e-09 37.4 0.0 5.4e-09 35.7 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 EER29525.1 - 1.5e-08 34.5 0.0 4.7e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2305 PF10230.4 EER29525.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EER29525.1 - 0.00022 20.8 0.3 0.00087 18.9 0.0 1.9 1 1 0 2 2 2 1 Lipase (class 3) PGAP1 PF07819.8 EER29525.1 - 0.00025 20.7 0.0 0.00068 19.2 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein PTPlike_phytase PF14566.1 EER29525.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF676 PF05057.9 EER29525.1 - 0.0021 17.3 0.0 0.01 15.1 0.0 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 EER29525.1 - 0.0074 16.5 0.1 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 EER29525.1 - 0.016 14.7 0.1 0.045 13.3 0.1 1.7 2 0 0 2 2 1 0 Serine hydrolase LCAT PF02450.10 EER29525.1 - 0.018 14.0 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Y_phosphatase PF00102.22 EER29525.1 - 0.035 13.4 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase FSH1 PF03959.8 EER29525.1 - 0.058 12.8 0.0 1 8.7 0.0 2.1 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.8 EER29525.1 - 0.071 11.3 0.2 1.1 7.4 0.1 2.1 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Ribosomal_S19e PF01090.14 EER29526.1 - 6.2e-57 190.9 0.2 7.1e-57 190.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Aldo_ket_red PF00248.16 EER29527.1 - 4.3e-48 163.5 0.0 6.2e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4184 PF13803.1 EER29527.1 - 0.063 12.5 0.6 0.14 11.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4184) eRF1_1 PF03463.10 EER29529.1 - 6.3e-46 155.2 0.1 1e-45 154.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EER29529.1 - 4.3e-18 65.6 0.0 8.9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EER29529.1 - 1.6e-17 64.0 0.0 4.4e-17 62.6 0.0 1.7 1 1 0 1 1 1 1 eRF1 domain 2 Myb_DNA-bind_4 PF13837.1 EER29530.1 - 8.8e-05 22.5 6.1 0.019 15.0 2.1 2.4 1 1 1 2 2 2 2 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 EER29530.1 - 0.019 14.9 1.5 0.04 13.9 1.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EER29530.1 - 0.02 14.7 6.9 0.053 13.4 0.4 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER29530.1 - 0.026 14.6 8.5 1.2 9.2 3.2 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_3 PF12776.2 EER29530.1 - 0.026 15.1 5.0 0.8 10.3 0.1 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER29531.1 - 2.2e-06 27.6 0.3 0.005 16.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER29531.1 - 0.062 13.3 3.3 0.35 10.9 2.4 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER29532.1 - 6.7e-14 51.6 3.6 6.8e-09 35.6 1.0 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EER29532.1 - 5.3e-12 45.6 3.6 8.7e-07 28.9 0.3 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 EER29532.1 - 3.8 5.6 13.7 3.8 5.6 9.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 COX5B PF01215.14 EER29533.1 - 2e-36 124.6 0.0 2.8e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.14 EER29533.1 - 0.24 10.9 2.9 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Myb_DNA-bind_6 PF13921.1 EER29534.1 - 2.8e-14 52.9 0.1 1.2e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EER29534.1 - 5.2e-12 45.6 0.1 1.5e-05 24.9 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain PEPCK PF00821.13 EER29535.1 - 0.026 12.7 0.0 0.033 12.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase PROCN PF08083.6 EER29536.1 - 6.3e-224 742.9 7.9 1.1e-223 742.0 5.5 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EER29536.1 - 2e-125 416.6 2.4 3.4e-125 415.9 1.7 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EER29536.1 - 1.4e-94 313.7 1.1 3.1e-94 312.6 0.8 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EER29536.1 - 3.2e-78 260.6 2.2 6.6e-78 259.6 0.8 2.1 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EER29536.1 - 7.5e-67 223.1 0.2 1.6e-66 222.0 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EER29536.1 - 3.4e-47 159.2 1.0 6.3e-47 158.3 0.1 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EER29536.1 - 4.6e-45 151.4 0.1 1.4e-44 149.8 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 DUF3753 PF12575.3 EER29536.1 - 0.11 12.2 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 EER29536.1 - 0.46 9.2 0.9 0.82 8.3 0.6 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.13 EER29537.1 - 3.2e-36 123.4 4.2 4.5e-36 122.9 2.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EER29537.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Fork_head PF00250.13 EER29538.1 - 1.6e-14 53.6 0.0 3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 EER29539.1 - 2.1e-67 226.1 4.3 4e-67 225.1 3.0 1.5 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EER29539.1 - 1.6e-54 182.7 7.0 3e-54 181.9 4.8 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein XLF PF09302.6 EER29540.1 - 1.5e-29 102.9 0.1 2.7e-29 102.1 0.1 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) WD40 PF00400.27 EER29541.1 - 4.7e-25 86.5 13.1 1e-11 44.2 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EER29541.1 - 0.0028 17.3 0.0 0.34 10.5 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A ABC_tran PF00005.22 EER29542.1 - 1e-31 110.0 0.0 3.6e-31 108.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EER29542.1 - 6e-29 101.3 9.4 6e-29 101.3 6.5 2.6 4 0 0 4 4 4 1 ABC transporter transmembrane region SMC_N PF02463.14 EER29542.1 - 6.2e-07 28.8 0.0 3.5e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EER29542.1 - 5.9e-05 23.1 0.2 0.054 13.4 0.1 2.3 1 1 1 2 2 2 2 AAA domain SbcCD_C PF13558.1 EER29542.1 - 0.0037 17.1 1.2 0.054 13.4 0.2 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EER29542.1 - 0.007 15.8 0.2 0.021 14.3 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EER29542.1 - 0.025 14.7 0.1 0.18 11.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EER29542.1 - 0.036 14.0 0.7 0.11 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EER29542.1 - 0.051 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pex24p PF06398.6 EER29542.1 - 1.1 7.9 5.6 0.23 10.2 1.4 1.6 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF498 PF04430.9 EER29543.1 - 1.6e-30 104.9 0.0 2.2e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 EER29544.1 - 1.5e-112 376.4 0.0 1.8e-112 376.1 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EER29544.1 - 0.00043 19.7 0.0 0.00092 18.6 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EER29544.1 - 0.012 15.3 0.2 0.03 14.0 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Ribosomal_S2 PF00318.15 EER29544.1 - 0.23 10.6 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 Glyco_hydro_16 PF00722.16 EER29545.1 - 1.7e-43 148.0 2.1 2.5e-43 147.5 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EER29545.1 - 0.025 14.5 15.3 0.052 13.5 10.6 1.5 1 0 0 1 1 1 0 Chitin recognition protein Pro_dh PF01619.13 EER29547.1 - 4.5e-36 124.4 0.0 6.1e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase PMSR PF01625.16 EER29548.1 - 2.6e-60 202.8 0.1 3.1e-60 202.5 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase KaiA PF07688.7 EER29548.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiA domain Kinesin PF00225.18 EER29549.1 - 4.8e-115 383.8 0.1 8.5e-115 383.0 0.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 EER29549.1 - 0.013 15.3 2.3 0.037 13.8 1.6 1.8 1 0 0 1 1 1 0 Herpesvirus UL14-like protein DUF543 PF04418.7 EER29551.1 - 0.046 13.6 1.0 0.14 12.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Con-6 PF10346.4 EER29553.1 - 4.7e-30 102.6 9.4 3.8e-15 55.0 0.8 2.2 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 EER29553.1 - 0.014 14.8 2.3 0.98 8.8 0.1 2.1 1 1 1 2 2 2 0 SpoIIIAH-like protein T4SS PF07996.6 EER29553.1 - 0.03 14.1 1.2 0.52 10.1 0.9 2.0 1 1 0 1 1 1 0 Type IV secretion system proteins DUF4230 PF14014.1 EER29553.1 - 3.1 7.6 4.7 24 4.7 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4230) ATP-synt_DE PF00401.15 EER29553.1 - 8.8 6.3 13.6 3.5 7.5 0.3 2.8 3 0 0 3 3 3 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain cNMP_binding PF00027.24 EER29555.1 - 8.7e-38 128.0 0.0 2.5e-20 72.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EER29555.1 - 8.3e-09 34.6 0.4 0.8 9.9 0.0 6.4 6 0 0 6 6 6 2 Leucine Rich repeat F-box PF00646.28 EER29555.1 - 4.8e-07 29.2 7.1 5.5e-07 29.0 0.8 3.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EER29555.1 - 7.8e-05 22.3 0.9 7.8e-05 22.3 0.7 2.6 3 0 0 3 3 3 1 F-box-like Ste50p-SAM PF09235.5 EER29555.1 - 0.014 15.4 0.6 5.1 7.1 0.0 3.8 3 1 1 4 4 4 0 Ste50p, sterile alpha motif Cupin_3 PF05899.7 EER29555.1 - 0.084 12.2 0.1 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) LRR_1 PF00560.28 EER29555.1 - 0.091 12.8 8.9 13 6.2 0.0 6.2 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_4 PF12799.2 EER29555.1 - 1.5 8.5 4.7 7.7 6.2 0.0 3.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EER29555.1 - 1.8 9.1 9.2 16 6.2 0.1 5.1 5 0 0 5 5 5 0 Leucine rich repeat Slx4 PF09494.5 EER29556.1 - 4.1e-27 93.6 0.3 6.9e-27 92.9 0.2 1.4 1 0 0 1 1 1 1 Slx4 endonuclease CGI-121 PF08617.5 EER29557.1 - 3.7e-56 189.2 0.1 4.3e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 5-FTHF_cyc-lig PF01812.15 EER29557.1 - 0.062 13.0 0.0 0.094 12.4 0.0 1.3 1 0 0 1 1 1 0 5-formyltetrahydrofolate cyclo-ligase family Bax1-I PF01027.15 EER29558.1 - 2.6e-28 99.0 10.6 3.9e-28 98.4 7.4 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Alpha-amylase PF00128.19 EER29559.1 - 6.7e-37 127.5 0.1 3.1e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF1966 PF09260.6 EER29559.1 - 5.8e-17 61.5 0.0 1.1e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) RRM_1 PF00076.17 EER29560.1 - 9.5e-17 60.3 0.0 1.5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29560.1 - 5.5e-12 45.4 0.0 9.9e-12 44.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29560.1 - 8.3e-10 38.3 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_76 PF03663.9 EER29561.1 - 2.1e-23 83.3 0.1 3.4e-15 56.3 0.0 3.5 3 1 1 4 4 4 3 Glycosyl hydrolase family 76 DUF2205 PF10224.4 EER29562.1 - 3.5e-27 93.7 0.8 6.5e-27 92.9 0.6 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 EER29562.1 - 0.00053 18.4 4.7 0.00063 18.1 3.3 1.0 1 0 0 1 1 1 1 Transmembrane protein Prefoldin PF02996.12 EER29562.1 - 0.0025 17.4 0.4 0.0046 16.6 0.3 1.5 1 0 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.4 EER29562.1 - 0.0045 16.8 1.3 0.0068 16.2 0.9 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 EER29562.1 - 0.012 13.4 1.0 0.015 13.1 0.7 1.1 1 0 0 1 1 1 0 HOOK protein IFT20 PF14931.1 EER29562.1 - 0.019 14.8 1.0 0.039 13.8 0.7 1.5 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF4201 PF13870.1 EER29562.1 - 0.019 14.4 0.9 0.028 13.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DivIC PF04977.10 EER29562.1 - 0.028 13.8 1.1 0.05 13.0 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator ADIP PF11559.3 EER29562.1 - 0.032 14.1 2.1 0.061 13.2 1.4 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EER29562.1 - 0.033 14.5 0.6 0.059 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF812 PF05667.6 EER29562.1 - 0.033 12.7 1.7 0.032 12.7 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4140 PF13600.1 EER29562.1 - 0.038 14.4 1.6 0.074 13.5 1.1 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AAA_32 PF13654.1 EER29562.1 - 0.047 12.3 0.3 0.052 12.1 0.2 1.1 1 0 0 1 1 1 0 AAA domain Glutaredoxin2_C PF04399.8 EER29562.1 - 0.084 12.4 0.1 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain HALZ PF02183.13 EER29562.1 - 0.096 12.4 4.2 1.2 8.9 0.1 2.4 1 1 1 2 2 2 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.7 EER29562.1 - 0.11 12.2 1.6 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus V_ATPase_I PF01496.14 EER29562.1 - 0.23 9.2 0.6 0.26 9.1 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CASP_C PF08172.7 EER29562.1 - 0.39 9.7 6.8 0.2 10.6 0.9 2.0 2 0 0 2 2 2 0 CASP C terminal ERM PF00769.14 EER29562.1 - 0.79 9.2 8.0 0.11 12.0 2.4 1.6 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Myf5 PF12232.3 EER29562.1 - 2.1 9.0 9.6 17 6.1 4.2 2.7 2 1 1 3 3 3 0 Myogenic determination factor 5 14-3-3 PF00244.15 EER29563.1 - 8.3e-117 388.3 6.5 9.4e-117 388.1 4.5 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF3461 PF11944.3 EER29563.1 - 0.31 10.9 4.0 0.98 9.2 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3461) IATP PF04568.7 EER29564.1 - 3.3e-25 88.0 0.7 3.9e-25 87.7 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NinG PF05766.7 EER29564.1 - 0.014 15.1 0.8 0.018 14.8 0.6 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Atg14 PF10186.4 EER29564.1 - 0.014 14.3 0.3 0.015 14.2 0.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OrfB_IS605 PF01385.14 EER29564.1 - 0.033 13.5 0.1 0.039 13.3 0.1 1.1 1 0 0 1 1 1 0 Probable transposase BLOC1_2 PF10046.4 EER29564.1 - 0.041 14.0 3.0 0.053 13.6 2.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EER29564.1 - 0.043 12.2 0.1 0.043 12.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF573 PF04504.9 EER29564.1 - 0.047 13.9 0.7 0.06 13.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DivIC PF04977.10 EER29564.1 - 0.17 11.3 3.8 0.26 10.7 2.6 1.3 1 0 0 1 1 1 0 Septum formation initiator DASH_Dad2 PF08654.5 EER29564.1 - 0.27 11.2 2.5 0.39 10.7 1.8 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad2 Syntaphilin PF15290.1 EER29564.1 - 0.29 10.5 3.5 0.36 10.2 2.4 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp DUF2968 PF11180.3 EER29564.1 - 5.2 6.4 7.6 8.3 5.7 4.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Nsp1_C PF05064.8 EER29565.1 - 6.2e-39 132.2 2.9 6.2e-39 132.2 2.0 1.6 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EER29565.1 - 0.00055 20.1 157.3 0.017 15.3 24.2 5.4 2 1 1 3 3 2 1 Nucleoporin FG repeat region ParB PF08775.5 EER29565.1 - 0.031 14.5 3.2 0.054 13.7 0.2 2.1 2 0 0 2 2 2 0 ParB family Baculo_PEP_C PF04513.7 EER29565.1 - 0.043 13.6 3.7 0.054 13.3 1.6 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EER29565.1 - 0.073 11.5 5.3 0.12 10.7 3.7 1.3 1 0 0 1 1 1 0 AAA domain MscS_porin PF12795.2 EER29565.1 - 0.093 12.0 18.7 0.013 14.8 5.1 2.2 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain APG6 PF04111.7 EER29565.1 - 0.22 10.5 8.5 0.31 10.0 5.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EER29565.1 - 0.53 10.1 8.7 0.12 12.2 3.4 1.7 1 1 1 2 2 2 0 Tropomyosin like LOH1CR12 PF10158.4 EER29565.1 - 0.56 10.0 1.9 2.7 7.8 0.2 2.2 1 1 2 3 3 3 0 Tumour suppressor protein CENP-Q PF13094.1 EER29565.1 - 0.61 10.1 10.2 1.6 8.7 7.1 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin PF00804.20 EER29565.1 - 6.9 6.8 6.5 47 4.2 4.5 2.1 1 1 0 1 1 1 0 Syntaxin zf-MIZ PF02891.15 EER29567.1 - 6.5e-11 41.5 0.2 1.6e-10 40.2 0.1 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PH PF00169.24 EER29568.1 - 8.9e-10 38.7 0.0 2.2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EER29568.1 - 1.4e-08 34.0 0.0 2.8e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH_11 PF15413.1 EER29568.1 - 4.7e-08 33.2 0.1 1.5e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_2 PF07647.12 EER29568.1 - 6.2e-08 32.3 0.0 1.1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EER29568.1 - 2e-07 30.4 0.1 3.8e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EER29568.1 - 0.0012 18.3 0.1 0.0024 17.3 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EER29568.1 - 0.0015 18.6 0.0 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EER29568.1 - 0.067 13.2 0.1 0.27 11.3 0.0 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Metallophos PF00149.23 EER29569.1 - 4e-09 36.1 3.2 1.6e-08 34.1 2.2 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L14 PF00238.14 EER29570.1 - 1.1e-33 115.6 0.0 1.2e-33 115.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 EER29571.1 - 3.7e-78 262.9 0.0 5.9e-78 262.2 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EER29572.1 - 7e-35 119.2 0.7 1.1e-34 118.5 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EER29572.1 - 3e-27 94.9 1.1 6.6e-27 93.8 0.8 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EER29572.1 - 6.9e-09 35.2 0.0 1.6e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain NIF PF03031.13 EER29573.1 - 6.1e-40 136.4 0.0 9.1e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EER29573.1 - 0.098 12.8 0.1 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Beta_elim_lyase PF01212.16 EER29574.1 - 3.4e-65 220.0 0.0 4.3e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EER29574.1 - 0.00014 20.9 0.0 0.0013 17.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EER29574.1 - 0.011 14.7 0.0 0.096 11.6 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EER29574.1 - 0.069 11.4 0.0 0.13 10.5 0.0 1.5 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.13 EER29575.1 - 2.9e-17 62.3 0.0 1.4e-16 60.1 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29575.1 - 1.4e-06 28.1 6.8 3.3e-06 26.9 4.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EER29576.1 - 0.002 17.8 0.1 0.0049 16.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER29576.1 - 0.0058 16.2 0.2 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 F-box domain DUF1399 PF07173.7 EER29577.1 - 4.5e-21 75.5 1.7 4.6e-17 62.5 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) M20_dimer PF07687.9 EER29577.1 - 0.13 11.9 0.0 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Peptidase dimerisation domain Fungal_trans PF04082.13 EER29578.1 - 8e-14 51.1 0.5 1.4e-13 50.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29578.1 - 4.4e-06 26.4 9.9 4.4e-06 26.4 6.9 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M28 PF04389.12 EER29579.1 - 1.4e-26 93.3 0.0 2.8e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EER29579.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EER29579.1 - 0.0087 15.3 0.0 0.13 11.4 0.0 2.2 2 0 0 2 2 2 1 Nicastrin AAA_29 PF13555.1 EER29579.1 - 0.072 12.6 0.3 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Peptidase_S8 PF00082.17 EER29581.1 - 4.4e-22 78.5 0.1 5.9e-22 78.1 0.1 1.2 1 0 0 1 1 1 1 Subtilase family Pkinase PF00069.20 EER29582.1 - 2.4e-69 233.3 0.0 3.2e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29582.1 - 3.3e-33 114.8 0.0 1.9e-31 109.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER29582.1 - 0.0017 17.3 0.4 0.51 9.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EER29582.1 - 0.0085 15.4 0.4 0.015 14.6 0.3 1.3 1 0 0 1 1 1 1 RIO1 family HAMP PF00672.20 EER29583.1 - 5.6e-46 154.5 16.9 2.4e-10 40.4 0.0 7.5 7 0 0 7 7 7 6 HAMP domain HATPase_c PF02518.21 EER29583.1 - 6.7e-31 106.2 0.8 1.9e-30 104.8 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EER29583.1 - 1.6e-27 95.7 1.3 6e-25 87.4 0.3 3.7 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.20 EER29583.1 - 2.8e-16 59.2 0.1 2.8e-16 59.2 0.0 4.3 5 0 0 5 5 5 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EER29583.1 - 0.017 13.6 28.1 0.17 10.3 0.8 4.2 1 1 2 4 4 4 0 AAA domain NAAA-beta PF15508.1 EER29583.1 - 0.024 14.9 1.8 16 5.9 0.1 5.5 5 1 1 7 7 7 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase CMD PF02627.15 EER29583.1 - 0.062 13.1 0.8 25 4.8 0.0 4.2 5 0 0 5 5 5 0 Carboxymuconolactone decarboxylase family DUF2365 PF10157.4 EER29583.1 - 2.5 7.9 21.2 18 5.2 0.1 7.1 7 3 1 8 8 8 0 Uncharacterized conserved protein (DUF2365) DUF948 PF06103.6 EER29583.1 - 4.4 7.2 36.2 2.9 7.8 0.2 8.5 4 2 3 8 8 8 0 Bacterial protein of unknown function (DUF948) Pox_A_type_inc PF04508.7 EER29583.1 - 5.4 7.0 6.7 1.1 9.2 0.1 3.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat NAD_binding_8 PF13450.1 EER29585.1 - 1.5e-11 44.1 0.2 3e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EER29585.1 - 4.1e-10 39.3 0.1 2e-09 37.0 0.1 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EER29585.1 - 7.6e-08 31.8 0.1 3.3e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 EER29585.1 - 4.5e-07 29.0 1.2 0.00082 18.3 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EER29585.1 - 1.5e-05 25.1 0.1 0.0022 18.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER29585.1 - 2.3e-05 24.6 2.1 0.0035 17.7 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EER29585.1 - 6.4e-05 22.1 0.3 0.0011 18.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 EER29585.1 - 0.00012 21.1 0.4 0.00012 21.1 0.3 1.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EER29585.1 - 0.00034 19.7 0.3 0.00069 18.7 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EER29585.1 - 0.00062 19.6 0.2 0.0012 18.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EER29585.1 - 0.0016 16.9 0.4 0.0016 16.9 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.11 EER29585.1 - 0.0076 15.7 0.3 0.015 14.7 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Collar PF07484.7 EER29585.1 - 0.038 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Phage Tail Collar Domain GIDA PF01134.17 EER29585.1 - 0.12 11.2 0.2 0.17 10.6 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A IlvN PF07991.7 EER29585.1 - 0.13 11.5 0.5 0.56 9.5 0.1 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain AA_permease_2 PF13520.1 EER29586.1 - 4.1e-28 98.0 30.1 4.8e-28 97.8 20.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER29586.1 - 3.1e-22 78.5 23.6 4.6e-22 78.0 16.3 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EER29587.1 - 6.6e-33 113.8 62.5 4.7e-27 94.6 28.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER29587.1 - 5.2e-11 41.7 38.3 1.4e-07 30.4 10.0 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EER29588.1 - 7.8e-24 84.0 25.3 2.6e-11 42.8 1.4 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EER29588.1 - 1.5e-14 53.4 16.4 4.3e-11 42.0 6.2 2.5 1 1 1 2 2 2 2 Sugar (and other) transporter tRNA-synt_2d PF01409.15 EER29589.1 - 1.3e-87 293.0 0.0 1.7e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EER29589.1 - 2.7e-05 23.1 1.8 0.00031 19.6 0.0 2.9 4 0 0 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EER29589.1 - 0.00065 19.3 0.0 0.0034 16.9 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EER29589.1 - 0.019 14.0 0.5 0.17 10.9 0.0 2.1 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Ribosomal_S21e PF01249.13 EER29590.1 - 3.4e-41 139.0 0.0 3.8e-41 138.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 EER29591.1 - 1.9e-17 63.1 0.0 3.3e-13 49.4 0.0 2.6 2 1 0 2 2 2 2 NUDIX domain IMPDH PF00478.20 EER29592.1 - 1.5e-132 441.8 1.5 1.7e-132 441.5 1.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EER29592.1 - 1.5e-19 69.4 0.1 4.3e-09 36.0 0.0 2.4 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EER29592.1 - 8e-07 28.2 0.4 1.5e-06 27.3 0.3 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EER29592.1 - 6.4e-05 22.2 10.8 0.076 12.1 5.8 2.5 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.16 EER29592.1 - 0.00086 18.6 2.5 0.012 14.8 1.7 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein PK PF00224.16 EER29592.1 - 0.0091 14.6 0.0 0.022 13.3 0.0 1.6 1 1 1 2 2 2 1 Pyruvate kinase, barrel domain ThiG PF05690.9 EER29592.1 - 0.078 12.0 2.0 0.096 11.7 0.4 1.8 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG RasGAP_C PF03836.10 EER29593.1 - 1.7e-48 163.9 3.1 4.3e-48 162.6 2.1 1.8 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EER29593.1 - 1.6e-39 135.6 0.0 4.1e-39 134.2 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EER29593.1 - 2e-18 64.1 57.8 0.035 13.7 0.7 15.9 17 0 0 17 17 17 10 IQ calmodulin-binding motif CH PF00307.26 EER29593.1 - 6.7e-12 45.4 0.0 1.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EER29593.1 - 0.072 12.7 0.0 0.25 11.0 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain ENTH PF01417.15 EER29594.1 - 1.2e-46 157.6 0.1 1.8e-46 157.0 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EER29594.1 - 7.1e-05 21.6 0.0 0.0001 21.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain PAT1 PF09770.4 EER29594.1 - 0.12 10.6 14.5 0.17 10.0 10.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SH3_1 PF00018.23 EER29595.1 - 4.5e-11 41.9 0.0 8.6e-11 41.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EER29595.1 - 1.5e-10 40.5 0.0 2.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EER29595.1 - 1.6e-07 30.7 0.0 2.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HMG-CoA_red PF00368.13 EER29597.1 - 1.9e-157 523.7 6.4 2.5e-157 523.3 4.4 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EER29597.1 - 3.7e-50 169.5 0.0 9.2e-50 168.3 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EER29597.1 - 6.8e-13 48.3 4.1 1.2e-11 44.3 2.9 2.4 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EER29597.1 - 0.00035 18.6 0.8 0.00035 18.6 0.5 1.8 2 0 0 2 2 2 1 Patched family GIT_SHD PF08518.6 EER29598.1 - 2.9e-18 64.8 3.8 8.5e-10 37.8 0.4 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT IncA PF04156.9 EER29598.1 - 0.057 13.0 44.7 0.058 12.9 15.7 3.1 3 0 0 3 3 3 0 IncA protein Macoilin PF09726.4 EER29598.1 - 0.23 9.7 35.8 0.82 7.8 24.2 2.2 1 1 1 2 2 2 0 Transmembrane protein DUF3584 PF12128.3 EER29598.1 - 0.47 7.7 35.1 0.83 6.9 24.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) K_channel_TID PF07941.6 EER29598.1 - 4.5 7.5 12.2 0.18 12.0 2.1 3.0 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Pro_isomerase PF00160.16 EER29599.1 - 6e-40 136.9 0.7 8.4e-40 136.5 0.5 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Flavin_Reduct PF01613.13 EER29599.1 - 0.023 14.5 0.5 0.038 13.8 0.4 1.3 1 0 0 1 1 1 0 Flavin reductase like domain RNase_PH PF01138.16 EER29600.1 - 1.6e-31 109.3 0.0 2.7e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Pkinase PF00069.20 EER29601.1 - 1e-13 51.0 0.0 3.3e-13 49.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29601.1 - 0.012 14.6 0.0 0.81 8.6 0.0 2.4 2 1 0 2 2 2 0 Protein tyrosine kinase SNF2_N PF00176.18 EER29602.1 - 3.6e-53 180.3 0.0 5.7e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EER29602.1 - 2.1e-28 98.0 0.5 5.4e-28 96.6 0.4 1.8 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EER29602.1 - 9.9e-15 54.1 0.0 5.2e-14 51.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EER29602.1 - 4.4e-07 29.5 0.0 8.4e-06 25.3 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EER29602.1 - 0.0055 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EER29602.1 - 0.37 10.6 0.0 0.37 10.6 0.0 3.2 4 1 0 4 4 4 0 Type III restriction enzyme, res subunit SEC-C PF02810.10 EER29602.1 - 2.1 7.9 11.3 5.2 6.7 7.8 1.7 1 1 0 1 1 1 0 SEC-C motif Ssu72 PF04722.8 EER29603.1 - 6.8e-84 280.0 0.0 8e-84 279.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Acyl-CoA_dh_1 PF00441.19 EER29604.1 - 8.8e-19 68.0 1.4 5.1e-18 65.6 1.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EER29604.1 - 2.5e-06 26.8 0.8 1.3e-05 24.6 0.6 2.1 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Isochorismatase PF00857.15 EER29605.1 - 7.6e-23 81.3 0.0 4.2e-22 78.8 0.0 1.9 1 1 0 1 1 1 1 Isochorismatase family DUF3605 PF12239.3 EER29606.1 - 1.6e-60 203.5 4.2 2e-60 203.2 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Oxysterol_BP PF01237.13 EER29607.1 - 1.7e-89 299.7 0.0 2.3e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Hist_deacetyl PF00850.14 EER29608.1 - 3.2e-77 259.8 0.0 4.6e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain ING PF12998.2 EER29609.1 - 6.4e-24 84.2 4.4 1.3e-23 83.2 3.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EER29609.1 - 1.9e-08 33.8 10.0 3.3e-08 33.1 6.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EER29609.1 - 0.01 15.9 0.4 0.025 14.7 0.3 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4200 PF13863.1 EER29609.1 - 0.49 10.3 4.5 1.3 8.9 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) RNA_pol_Rpc34 PF05158.7 EER29610.1 - 7.3e-110 367.1 0.0 7.9e-110 367.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 EER29610.1 - 0.046 13.8 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR PF03551.9 EER29610.1 - 0.057 13.1 0.2 0.27 11.0 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family TPR_11 PF13414.1 EER29611.1 - 1.2e-51 172.2 24.7 4.7e-15 55.0 0.1 6.3 5 1 0 6 6 6 5 TPR repeat TPR_1 PF00515.23 EER29611.1 - 8.9e-40 132.7 23.8 1.2e-05 24.7 0.0 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EER29611.1 - 5.8e-30 100.7 23.4 8.9e-05 22.1 0.0 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.1 EER29611.1 - 9.2e-16 57.5 13.3 2.4e-08 33.7 0.1 5.7 3 3 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER29611.1 - 2.5e-15 56.6 20.6 0.00062 20.3 0.1 6.7 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 EER29611.1 - 5.7e-15 53.9 13.6 0.0092 15.6 0.0 7.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EER29611.1 - 1.3e-13 50.2 16.9 0.018 15.6 0.1 9.8 5 3 5 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EER29611.1 - 4.1e-11 43.0 13.3 0.013 15.8 0.4 6.3 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EER29611.1 - 1.8e-09 37.0 7.2 0.36 11.1 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EER29611.1 - 1.5e-08 34.3 4.4 0.0033 17.2 0.6 4.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER29611.1 - 2.5e-07 30.0 8.0 0.63 9.9 0.1 7.2 6 1 1 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EER29611.1 - 5.9e-07 29.5 11.0 0.00028 20.9 0.7 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Inhibitor_I9 PF05922.11 EER29611.1 - 0.0034 17.9 0.1 0.017 15.7 0.0 2.3 2 0 0 2 2 1 1 Peptidase inhibitor I9 TPR_6 PF13174.1 EER29611.1 - 0.0038 17.5 13.2 14 6.4 0.0 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EER29611.1 - 0.035 13.9 6.5 3.2 7.7 0.0 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EER29611.1 - 0.78 9.7 3.4 16 5.5 0.0 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EER29611.1 - 1.7 7.9 5.4 12 5.2 0.1 4.6 6 0 0 6 6 6 0 SHNi-TPR C2 PF00168.25 EER29612.1 - 9.1e-66 217.7 3.0 2.4e-20 72.1 0.0 5.6 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EER29612.1 - 0.055 13.6 0.7 0.41 10.8 0.0 2.7 3 0 0 3 3 3 0 Putative integral membrane protein conserved region (DUF2404) DUF2256 PF10013.4 EER29612.1 - 0.19 11.4 0.1 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) adh_short PF00106.20 EER29613.1 - 1.8e-18 67.0 0.0 1.5e-17 63.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER29613.1 - 3.2e-06 26.9 0.0 0.0041 16.7 0.0 2.2 2 0 0 2 2 2 2 KR domain Eno-Rase_NADH_b PF12242.3 EER29613.1 - 0.031 14.0 0.1 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RRM_1 PF00076.17 EER29614.1 - 5.2e-16 58.0 0.0 2.5e-12 46.2 0.0 3.0 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29614.1 - 6.9e-15 54.7 0.0 2.4e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29614.1 - 2.5e-10 40.0 0.0 1.9e-06 27.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UDPGP PF01704.13 EER29615.1 - 7.2e-181 601.2 0.1 8.4e-181 601.0 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase zf-CCCH PF00642.19 EER29617.1 - 7.5e-09 35.0 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EER29617.1 - 0.00014 21.5 0.0 0.00025 20.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER29617.1 - 0.009 15.6 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29617.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4185 PF13810.1 EER29618.1 - 0.0074 15.2 0.6 0.011 14.6 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Amidase PF01425.16 EER29619.1 - 2e-88 297.1 0.0 3.1e-88 296.5 0.0 1.3 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.11 EER29620.1 - 7.4e-11 41.3 15.0 7.4e-11 41.3 10.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Epimerase PF01370.16 EER29621.1 - 3.4e-08 33.2 0.0 5.2e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EER29621.1 - 4.3e-05 23.5 0.0 7.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EER29621.1 - 0.042 12.7 0.0 7.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein Fungal_trans PF04082.13 EER29622.1 - 1.1e-07 31.0 0.0 2.4e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29622.1 - 2.8e-05 23.9 12.6 4.8e-05 23.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYVE PF01363.16 EER29623.1 - 4.8e-21 74.4 2.6 4.8e-21 74.4 1.8 3.3 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EER29623.1 - 1.5e-08 34.3 5.8 1.5e-08 34.3 4.0 3.5 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EER29623.1 - 0.0076 16.3 5.9 0.0076 16.3 4.1 3.2 3 0 0 3 3 3 1 RING-H2 zinc finger FYVE_2 PF02318.11 EER29623.1 - 0.016 15.1 1.1 0.016 15.1 0.8 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger TRP PF06011.7 EER29624.1 - 2.7e-86 289.8 28.5 1.1e-85 287.8 19.8 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EER29624.1 - 1.6e-18 67.1 0.0 2.3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF4109 PF13397.1 EER29625.1 - 0.065 13.6 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) Cys_Met_Meta_PP PF01053.15 EER29626.1 - 1.1e-62 211.6 0.0 2.7e-62 210.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EER29626.1 - 0.00025 20.1 0.0 0.00053 19.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EER29626.1 - 0.0014 17.4 0.0 0.0025 16.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EER29626.1 - 0.062 12.3 0.0 7.2 5.5 0.0 2.6 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family EcoEI_R_C PF08463.5 EER29626.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal GFA PF04828.9 EER29627.1 - 1.8e-21 75.8 1.2 1.8e-21 75.8 0.9 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme zf-CSL PF05207.8 EER29627.1 - 0.058 12.9 5.7 0.15 11.5 2.0 2.2 2 0 0 2 2 2 0 CSL zinc finger Fungal_trans PF04082.13 EER29628.1 - 8.2e-13 47.8 0.1 1.4e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29628.1 - 8.3e-11 41.6 7.7 1.5e-10 40.7 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 EER29629.1 - 3.8e-30 104.6 30.8 5.6e-30 104.0 21.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EER29629.1 - 1.2e-25 90.3 0.2 1.9e-25 89.7 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EER29629.1 - 5.8e-09 36.3 2.3 4e-07 30.3 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EER29629.1 - 5.3e-06 26.5 0.0 8.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EER29629.1 - 2.3e-05 23.7 0.4 4.1e-05 22.9 0.3 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EER29629.1 - 0.0001 21.5 0.1 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EER29629.1 - 0.00029 20.3 0.1 0.00058 19.3 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EER29629.1 - 0.00057 20.0 0.1 0.0022 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EER29629.1 - 0.001 18.4 0.0 0.0024 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EER29629.1 - 0.002 17.2 0.0 0.16 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EER29629.1 - 0.0023 17.6 0.0 0.0058 16.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EER29629.1 - 0.0033 16.8 0.1 0.011 15.2 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.1 EER29629.1 - 0.0042 16.5 0.1 0.0093 15.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EER29629.1 - 0.0046 17.7 0.0 0.0089 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EER29629.1 - 0.0049 16.7 0.0 0.0089 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EER29629.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_10 PF12846.2 EER29629.1 - 0.0095 15.3 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_28 PF13521.1 EER29629.1 - 0.0098 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EER29629.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EER29629.1 - 0.016 14.1 0.1 0.026 13.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EER29629.1 - 0.018 15.2 0.1 0.11 12.6 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EER29629.1 - 0.02 14.8 0.7 0.52 10.2 0.1 2.4 1 1 1 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 EER29629.1 - 0.031 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 EER29629.1 - 0.055 11.9 0.3 0.65 8.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EER29629.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EER29629.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EER29629.1 - 0.073 13.0 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EER29629.1 - 0.091 12.6 0.0 0.26 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain SRP54 PF00448.17 EER29629.1 - 0.099 12.0 0.2 0.47 9.8 0.0 2.0 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EER29629.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EER29629.1 - 0.12 12.0 0.1 0.41 10.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mannosyl_trans3 PF11051.3 EER29630.1 - 8.4e-77 258.1 0.0 9.1e-76 254.7 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative DPPIV_N PF00930.16 EER29631.1 - 1.9e-113 378.6 1.5 2.6e-113 378.2 1.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EER29631.1 - 6.8e-40 136.5 1.5 1.2e-39 135.7 1.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EER29631.1 - 7.8e-07 28.9 0.1 1.9e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family PD40 PF07676.7 EER29631.1 - 0.0082 15.7 0.3 1.8 8.3 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Abhydrolase_6 PF12697.2 EER29631.1 - 0.0095 15.8 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EER29631.1 - 0.017 13.6 0.0 0.035 12.6 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S28 PF05577.7 EER29631.1 - 0.025 13.1 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 MAPEG PF01124.13 EER29632.1 - 1.5e-13 50.4 1.9 1.7e-13 50.2 1.3 1.1 1 0 0 1 1 1 1 MAPEG family MARVEL PF01284.18 EER29633.1 - 1.5e-06 28.1 11.9 3.2e-06 27.0 8.1 1.6 1 1 0 1 1 1 1 Membrane-associating domain CytB6-F_Fe-S PF08802.5 EER29633.1 - 0.013 15.5 0.6 0.013 15.5 0.4 2.0 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Phospholip_A2_3 PF09056.6 EER29634.1 - 4.2e-42 142.8 5.6 6.3e-42 142.2 3.9 1.3 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 Methyltransf_16 PF10294.4 EER29635.1 - 1.8e-11 43.8 0.0 6.5e-06 25.7 0.0 2.3 2 0 0 2 2 2 2 Putative methyltransferase HSP70 PF00012.15 EER29636.1 - 1.1e-263 875.7 17.5 1.2e-263 875.4 12.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EER29636.1 - 4.8e-15 54.9 6.3 3.1e-13 49.0 1.9 2.5 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EER29636.1 - 0.00058 19.5 0.1 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EER29636.1 - 0.0012 18.6 12.4 0.32 10.8 0.0 5.0 3 3 0 3 3 3 2 Cell division protein FtsA DUF4363 PF14276.1 EER29636.1 - 0.0051 16.5 2.2 0.011 15.4 1.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4363) DnaG_DnaB_bind PF08278.6 EER29636.1 - 0.31 11.2 10.7 0.025 14.7 2.6 2.7 3 1 1 4 4 4 0 DNA primase DnaG DnaB-binding DUF2415 PF10313.4 EER29637.1 - 6.6e-16 57.7 0.0 1.4e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) PcrB PF01884.12 EER29637.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 PcrB family WD40 PF00400.27 EER29637.1 - 0.47 10.4 3.3 5 7.1 0.4 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat DSHCT PF08148.7 EER29638.1 - 2.3e-60 202.9 0.6 4.5e-60 201.9 0.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EER29638.1 - 4.3e-20 71.8 0.0 9.6e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER29638.1 - 8.6e-07 28.7 0.0 2.4e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER29638.1 - 0.012 15.4 0.7 0.18 11.6 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit GRP PF07172.6 EER29638.1 - 8.3 6.9 14.1 21 5.6 9.8 1.6 1 0 0 1 1 1 0 Glycine rich protein family IBN_N PF03810.14 EER29639.1 - 4.6e-15 55.2 5.1 2.5e-12 46.5 0.0 5.1 5 0 0 5 5 5 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EER29639.1 - 4.4e-08 33.1 1.2 3.9e-05 23.5 0.0 4.2 4 0 0 4 4 4 1 Exportin 1-like protein Cse1 PF08506.5 EER29639.1 - 5.6e-07 28.4 0.0 1.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Cse1 DUF2435 PF10363.4 EER29639.1 - 9e-05 22.3 2.2 0.014 15.2 0.3 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 EER29639.1 - 0.0002 21.5 0.6 0.031 14.5 0.1 3.2 2 1 1 3 3 3 1 HEAT repeats MOR2-PAG1_C PF14225.1 EER29639.1 - 0.019 14.7 0.2 0.33 10.6 0.1 2.5 2 0 0 2 2 2 0 Cell morphogenesis C-terminal HEAT_EZ PF13513.1 EER29639.1 - 0.13 12.7 9.1 0.75 10.3 0.1 5.9 7 0 0 7 7 7 0 HEAT-like repeat RRM_1 PF00076.17 EER29640.1 - 1e-08 34.6 0.1 3.7e-08 32.8 0.0 2.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29640.1 - 7e-08 32.3 0.0 2e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EER29640.1 - 0.0031 17.2 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1886 PF09171.5 EER29640.1 - 0.015 14.3 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) ATG16 PF08614.6 EER29641.1 - 0.0037 17.1 3.6 0.0075 16.1 0.2 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DivIC PF04977.10 EER29641.1 - 0.023 14.1 2.5 0.045 13.2 0.1 2.1 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 EER29641.1 - 0.093 13.1 3.7 4.5 7.7 0.2 2.4 2 0 0 2 2 2 0 SlyX DivIVA PF05103.8 EER29641.1 - 0.19 11.7 2.1 0.51 10.3 0.1 2.0 2 0 0 2 2 2 0 DivIVA protein Filament PF00038.16 EER29641.1 - 0.23 10.9 5.6 0.12 11.8 0.9 1.9 2 0 0 2 2 2 0 Intermediate filament protein DUF4140 PF13600.1 EER29641.1 - 1.8 9.0 6.6 2 8.8 1.3 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) PP2C_2 PF13672.1 EER29641.1 - 2.1 7.6 5.8 0.39 10.0 1.3 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C DUF1168 PF06658.7 EER29642.1 - 0.09 12.2 22.3 0.39 10.2 8.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) DUF501 PF04417.7 EER29642.1 - 4.1 7.2 8.4 0.11 12.3 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF501) U79_P34 PF03064.11 EER29642.1 - 4.6 6.6 14.1 0.61 9.5 4.4 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Peptidase_S49_N PF08496.5 EER29642.1 - 6.3 6.5 12.8 2.3 7.9 4.1 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Menin PF05053.8 EER29642.1 - 6.5 4.7 10.0 16 3.4 6.9 1.6 1 0 0 1 1 1 0 Menin RRM_5 PF13893.1 EER29643.1 - 0.00094 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EER29643.1 - 0.0055 16.3 0.0 0.0099 15.5 0.0 1.4 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_6 PF14259.1 EER29643.1 - 0.039 13.9 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER29643.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EER29645.1 - 1.4e-30 106.2 30.6 1.3e-28 99.7 11.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER29645.1 - 4.6e-10 38.6 7.9 4.6e-10 38.6 5.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Kinetocho_Slk19 PF12709.2 EER29646.1 - 1.8e-22 79.1 29.0 3.3e-21 75.1 5.5 4.2 4 0 0 4 4 4 2 Central kinetochore-associated DUF4200 PF13863.1 EER29646.1 - 0.0092 15.9 11.3 0.0092 15.9 7.8 4.1 2 2 1 4 4 4 1 Domain of unknown function (DUF4200) DUF208 PF02677.9 EER29646.1 - 0.083 12.6 6.2 0.21 11.3 4.3 1.7 1 0 0 1 1 1 0 Uncharacterized BCR, COG1636 FlxA PF14282.1 EER29646.1 - 1.5 8.8 24.0 1.6 8.7 4.0 3.3 2 1 0 3 3 3 0 FlxA-like protein Reo_sigmaC PF04582.7 EER29646.1 - 4.8 6.2 14.4 8.8 5.4 0.1 3.1 2 1 0 3 3 3 0 Reovirus sigma C capsid protein FAD_binding_3 PF01494.14 EER29647.1 - 3e-10 39.6 0.0 1.2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EER29647.1 - 0.00056 18.9 0.2 0.005 15.7 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EER29647.1 - 0.013 14.4 0.0 17 4.1 0.0 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EER29647.1 - 0.02 14.9 0.4 0.079 12.9 0.3 2.1 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Phage_int_SAM_5 PF13102.1 EER29647.1 - 0.02 14.8 0.1 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Phage integrase SAM-like domain SE PF08491.5 EER29647.1 - 0.032 13.0 0.0 0.088 11.6 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.1 EER29647.1 - 0.11 12.3 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Fungal_trans PF04082.13 EER29649.1 - 6.6e-35 120.2 1.6 1.1e-34 119.4 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29649.1 - 0.0015 18.4 17.0 0.0028 17.5 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Toxin_62 PF15540.1 EER29649.1 - 0.053 13.6 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Putative toxin 62 Peptidase_S10 PF00450.17 EER29650.1 - 4.3e-99 332.4 0.4 5e-99 332.2 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 EER29651.1 - 1.8e-17 63.0 28.5 3.1e-17 62.3 19.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EER29651.1 - 8.8e-11 41.5 4.0 3.2e-10 39.7 2.8 2.0 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Amidohydro_4 PF13147.1 EER29652.1 - 4.1e-14 53.2 1.2 1.3e-13 51.5 0.8 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EER29652.1 - 2.5e-09 37.2 0.2 1.9e-08 34.3 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EER29652.1 - 2.2e-05 23.8 0.1 4e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EER29652.1 - 8.8e-05 22.2 0.6 0.0008 19.1 0.0 2.6 3 0 0 3 3 3 1 Amidohydrolase GMC_oxred_N PF00732.14 EER29653.1 - 9e-50 169.4 0.0 1.1e-49 169.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EER29653.1 - 4.6e-39 133.9 0.0 7.2e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EER29653.1 - 3e-06 26.3 0.1 0.00017 20.5 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EER29653.1 - 6.9e-05 21.9 0.0 9.9e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EER29653.1 - 0.00049 19.0 0.1 0.15 10.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EER29653.1 - 0.002 18.1 0.1 0.0059 16.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EER29653.1 - 0.0081 14.8 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EER29653.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EER29653.1 - 0.094 11.7 0.1 1.3 8.0 0.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Aldedh PF00171.17 EER29654.1 - 3.6e-158 526.7 0.0 4.1e-158 526.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.15 EER29655.1 - 8.3e-27 94.2 0.0 1.3e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 EER29656.1 - 2.2e-59 200.9 0.0 3e-59 200.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EER29656.1 - 0.00014 21.7 0.0 0.00062 19.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Glyco_hydro_3_C PF01915.17 EER29656.1 - 0.0022 17.5 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_7 PF13508.1 EER29656.1 - 0.055 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EER29656.1 - 0.095 12.6 0.0 0.29 11.0 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NDT80_PhoG PF05224.7 EER29657.1 - 5.1e-36 124.4 0.3 1.4e-35 123.0 0.0 1.9 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hexokinase_1 PF00349.16 EER29658.1 - 2.5e-37 128.1 0.0 3.8e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EER29658.1 - 5.6e-30 104.3 0.0 9.6e-24 83.9 0.0 2.8 2 1 1 3 3 3 2 Hexokinase Peptidase_S46 PF10459.4 EER29658.1 - 0.012 14.0 0.0 0.018 13.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase S46 p450 PF00067.17 EER29659.1 - 2.7e-59 200.9 0.0 3.5e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EER29660.1 - 2.3e-14 53.4 0.0 4.6e-14 52.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER29660.1 - 1.9e-08 34.6 0.0 4.1e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER29660.1 - 4.4e-07 29.6 0.0 1.7e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER29660.1 - 7.8e-05 23.0 0.0 0.00028 21.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER29660.1 - 0.00066 20.2 0.0 0.0057 17.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EER29660.1 - 0.00079 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.13 EER29660.1 - 0.0015 17.7 0.0 0.0042 16.2 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EER29660.1 - 0.0078 16.5 0.0 0.019 15.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain COX14 PF14880.1 EER29661.1 - 5.3e-19 67.5 0.0 5.3e-19 67.5 0.0 2.8 4 0 0 4 4 4 1 Cytochrome oxidase c assembly GAD PF02938.9 EER29661.1 - 0.011 15.8 0.9 0.023 14.8 0.6 1.5 1 0 0 1 1 1 0 GAD domain Ribosomal_S8e PF01201.17 EER29661.1 - 0.054 13.6 2.2 0.95 9.6 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S8e HA PF03457.9 EER29661.1 - 0.056 13.5 0.1 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 Helicase associated domain Usp PF00582.21 EER29661.1 - 0.068 13.3 3.0 0.055 13.6 0.8 1.7 2 0 0 2 2 2 0 Universal stress protein family DUF2458 PF10454.4 EER29662.1 - 1.5e-47 161.2 0.1 2.1e-47 160.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DAHP_synth_1 PF00793.15 EER29663.1 - 3.7e-97 324.2 0.0 4.6e-97 323.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Thiolase_N PF00108.18 EER29665.1 - 1.5e-77 260.1 0.1 2.5e-77 259.4 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EER29665.1 - 9.6e-47 157.4 0.5 9.6e-47 157.4 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EER29665.1 - 0.065 12.7 1.7 0.16 11.4 0.7 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Ribosomal_L50 PF10501.4 EER29666.1 - 9.1e-21 73.9 0.0 1.9e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S Rtf2 PF04641.7 EER29667.1 - 1.1e-67 227.9 2.9 1.3e-67 227.7 2.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EER29667.1 - 7.5e-08 31.7 0.7 0.0064 15.9 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EER29667.1 - 1.4e-05 24.6 2.1 1.6e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EER29667.1 - 0.0027 17.3 0.6 0.0078 15.9 0.4 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EER29667.1 - 0.082 12.7 1.6 0.15 11.9 0.4 2.0 2 1 0 2 2 2 0 Ring finger domain PRKCSH-like PF12999.2 EER29668.1 - 3.3e-48 163.5 6.5 2.7e-28 98.7 1.5 2.9 3 0 0 3 3 3 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EER29668.1 - 1.9e-31 108.6 0.3 1.9e-31 108.6 0.2 2.4 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EER29668.1 - 2.1e-08 34.8 0.2 7e-08 33.1 0.1 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Fib_alpha PF08702.5 EER29668.1 - 0.045 13.8 6.7 1.1 9.3 3.1 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Mit_KHE1 PF10173.4 EER29668.1 - 0.15 11.8 0.3 0.33 10.7 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Macoilin PF09726.4 EER29668.1 - 0.98 7.6 9.8 1.7 6.8 6.8 1.3 1 0 0 1 1 1 0 Transmembrane protein Fzo_mitofusin PF04799.8 EER29668.1 - 1.4 8.2 5.3 2.2 7.6 1.7 2.2 1 1 1 2 2 2 0 fzo-like conserved region DUF4407 PF14362.1 EER29668.1 - 2.6 6.8 9.0 1.4 7.7 4.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HSCB_C PF07743.8 EER29668.1 - 4.1 7.9 12.9 0.94 9.9 2.6 3.4 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain PAP_assoc PF03828.14 EER29669.1 - 8.3e-14 51.2 1.1 1.6e-13 50.3 0.2 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EER29669.1 - 4.3e-09 36.5 0.0 9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Aldo_ket_red PF00248.16 EER29670.1 - 1.2e-63 214.5 0.0 1.6e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 EER29671.1 - 3.2e-06 26.9 0.1 3.2e-06 26.9 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cytochrome_C554 PF13435.1 EER29671.1 - 0.024 14.6 0.3 0.032 14.2 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime DUF4428 PF14471.1 EER29671.1 - 0.14 11.8 1.5 0.72 9.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) PhyH PF05721.8 EER29674.1 - 1.9e-29 103.2 0.0 2.6e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Ni_hydr_CYTB PF01292.15 EER29675.1 - 1.8 7.9 7.8 2.7 7.3 5.4 1.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 VKOR PF07884.9 EER29675.1 - 10 6.0 11.9 2 8.2 0.3 2.9 1 1 2 3 3 3 0 Vitamin K epoxide reductase family Pex24p PF06398.6 EER29676.1 - 7.4e-98 327.6 0.9 9.9e-98 327.2 0.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Secretin_N PF03958.12 EER29676.1 - 0.011 15.8 0.3 0.027 14.6 0.2 1.7 1 0 0 1 1 1 0 Bacterial type II/III secretion system short domain DUF4588 PF15251.1 EER29676.1 - 0.073 13.0 5.6 0.13 12.1 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) Pam16 PF03656.8 EER29677.1 - 1.4e-35 121.8 0.8 1.5e-35 121.7 0.6 1.0 1 0 0 1 1 1 1 Pam16 RNA_pol_Rpb4 PF03874.11 EER29677.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb4 DUF706 PF05153.10 EER29678.1 - 2.9e-126 419.9 0.7 3.6e-126 419.6 0.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EER29678.1 - 0.033 14.2 0.4 0.3 11.1 0.1 2.5 1 1 0 1 1 1 0 HD domain Alpha-E PF04168.7 EER29678.1 - 0.052 12.9 0.2 0.075 12.3 0.2 1.2 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Aldo_ket_red PF00248.16 EER29679.1 - 2.3e-50 171.0 0.0 2.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Stanniocalcin PF03298.8 EER29681.1 - 6.1e-05 22.1 0.3 8e-05 21.7 0.2 1.2 1 0 0 1 1 1 1 Stanniocalcin family Methyltransf_31 PF13847.1 EER29683.1 - 8.7e-11 41.6 0.0 1.2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER29683.1 - 1.3e-10 41.8 0.1 2.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER29683.1 - 3.4e-10 39.8 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER29683.1 - 1.2e-09 38.4 0.0 3.4e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER29683.1 - 1.5e-07 31.4 0.1 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER29683.1 - 9.8e-07 29.1 0.0 1.6e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EER29683.1 - 1.4e-05 25.3 0.0 3.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EER29683.1 - 4.5e-05 23.4 0.0 6.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_16 PF10294.4 EER29683.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EER29683.1 - 0.0016 17.5 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EER29683.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FAT PF02259.18 EER29685.1 - 1.5e-127 425.4 10.6 1.5e-127 425.4 7.3 2.3 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 EER29685.1 - 1.5e-63 213.5 4.9 9.7e-59 197.8 0.7 4.0 3 0 0 3 3 3 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EER29685.1 - 1.1e-57 195.1 0.4 2.6e-57 194.0 0.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EER29685.1 - 1.5e-39 134.1 2.0 5.1e-39 132.3 0.1 3.2 3 0 0 3 3 2 1 Rapamycin binding domain HEAT_2 PF13646.1 EER29685.1 - 1.8e-19 69.7 21.2 0.00041 20.5 0.0 8.3 7 1 1 8 8 7 5 HEAT repeats FATC PF02260.15 EER29685.1 - 4.2e-15 54.8 0.3 1e-14 53.6 0.2 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EER29685.1 - 2.3e-14 52.0 24.8 0.0029 17.5 0.0 12.8 13 0 0 13 13 12 4 HEAT repeat HEAT_EZ PF13513.1 EER29685.1 - 2.6e-12 46.8 15.0 0.0036 17.7 0.0 11.2 9 2 2 11 11 11 3 HEAT-like repeat UME PF08064.8 EER29685.1 - 0.0001 22.2 6.4 5.3 7.0 0.1 7.0 5 1 2 7 7 7 1 UME (NUC010) domain Vac14_Fab1_bd PF12755.2 EER29685.1 - 0.0016 18.8 7.9 33 4.9 0.0 8.1 7 1 2 10 10 10 0 Vacuolar 14 Fab1-binding region TPR_7 PF13176.1 EER29685.1 - 0.15 11.9 4.6 16 5.5 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Mit_ribos_Mrp51 PF11709.3 EER29686.1 - 1.9e-89 299.9 0.1 2.3e-89 299.7 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit SHOCT PF09851.4 EER29686.1 - 3.9 7.0 5.7 0.7 9.4 0.1 2.7 3 0 0 3 3 3 0 Short C-terminal domain Ribosomal_S17e PF00833.13 EER29687.1 - 1.7e-58 195.7 0.7 2e-58 195.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EER29687.1 - 0.066 13.9 0.0 0.085 13.5 0.0 1.3 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 EER29688.1 - 1.5e-18 66.6 0.0 2.5e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_1 PF00018.23 EER29689.1 - 1.8e-09 36.8 0.3 1.8e-09 36.8 0.2 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EER29689.1 - 2.2e-09 36.7 0.1 5.7e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EER29689.1 - 1.8e-08 33.7 0.1 3.4e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Nop14 PF04147.7 EER29689.1 - 1.1 7.1 15.5 1.7 6.4 10.7 1.2 1 0 0 1 1 1 0 Nop14-like family Adaptin_N PF01602.15 EER29690.1 - 1e-129 433.3 5.0 1.2e-129 433.0 3.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EER29690.1 - 3.6e-18 66.0 1.9 1.1e-16 61.1 0.0 3.2 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EER29690.1 - 6.2e-18 64.8 2.4 1.6e-11 44.3 0.1 4.5 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EER29690.1 - 1.5e-10 40.1 5.8 0.015 15.3 0.0 5.3 6 0 0 6 6 6 3 HEAT repeat Atx10homo_assoc PF09759.4 EER29690.1 - 3.4e-06 26.7 0.4 1.4 8.7 0.0 4.8 4 1 0 5 5 5 2 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EER29690.1 - 7.6e-05 22.3 2.9 1.8 8.5 0.0 5.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EER29690.1 - 0.00028 21.2 10.9 1.3 9.5 0.0 6.1 5 1 1 6 6 6 2 HEAT-like repeat T_hemolysin PF12261.3 EER29690.1 - 0.011 15.3 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 Thermostable hemolysin CLASP_N PF12348.3 EER29690.1 - 0.015 14.6 1.1 5.6 6.2 0.0 3.3 3 1 0 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.2 EER29690.1 - 0.06 13.7 0.9 1.5 9.2 0.0 3.4 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region DUF2435 PF10363.4 EER29690.1 - 0.11 12.4 1.0 2 8.3 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) DUF1077 PF06417.7 EER29691.1 - 3.9e-45 152.2 6.7 5.1e-45 151.8 4.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Aminotran_5 PF00266.14 EER29692.1 - 1.1e-10 40.8 0.0 8.3e-10 37.9 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EER29692.1 - 0.035 13.1 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Lactamase_B PF00753.22 EER29693.1 - 6.5e-09 35.7 0.0 2.3e-07 30.6 0.0 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EER29693.1 - 0.0091 15.5 0.1 0.012 15.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Hemerythrin PF01814.18 EER29694.1 - 2.8e-11 43.6 0.3 3.8e-11 43.2 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain NAAA-beta PF15508.1 EER29694.1 - 0.048 14.0 0.3 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Fe-S_biosyn PF01521.15 EER29695.1 - 4.8e-09 36.1 0.1 0.00068 19.5 0.0 2.6 2 1 1 3 3 3 2 Iron-sulphur cluster biosynthesis Paf67 PF10255.4 EER29696.1 - 2.2e-154 514.1 0.0 2.6e-154 513.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EER29696.1 - 0.0059 16.4 0.1 0.09 12.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat RRM_6 PF14259.1 EER29697.1 - 0.00087 19.2 0.0 0.38 10.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DOMON PF03351.12 EER29698.1 - 0.00019 21.3 0.2 0.00058 19.7 0.0 1.9 2 0 0 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.11 EER29698.1 - 0.00037 20.3 7.1 0.00089 19.1 4.9 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PDH PF02153.12 EER29699.1 - 1.6e-12 46.8 0.0 2.3e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EER29699.1 - 1.6e-05 24.7 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EER29699.1 - 2e-05 24.9 0.0 4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EER29699.1 - 0.0016 17.6 0.0 0.0027 16.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EER29699.1 - 0.002 17.5 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EER29699.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.6 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EER29699.1 - 0.043 13.8 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Rossmann-like PF10727.4 EER29699.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Ribosomal_S11 PF00411.14 EER29700.1 - 1e-40 138.3 0.4 1.2e-40 138.0 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 AAR2 PF05282.6 EER29701.1 - 3.6e-94 315.6 0.0 4.5e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S9 PF00380.14 EER29702.1 - 2.8e-41 140.5 0.4 3.1e-41 140.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13 PF00572.13 EER29703.1 - 4.3e-41 139.9 0.0 5.7e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Uricase PF01014.13 EER29704.1 - 7.6e-79 262.5 0.3 6.3e-47 159.1 0.5 2.0 2 0 0 2 2 2 2 Uricase RICTOR_N PF14664.1 EER29705.1 - 7.4e-136 452.5 0.1 1.7e-135 451.3 0.1 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EER29705.1 - 1.8e-86 288.8 2.1 6.8e-86 286.9 0.6 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EER29705.1 - 1.1e-41 141.4 0.4 1.6e-40 137.6 0.0 3.3 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EER29705.1 - 6.4e-24 83.6 1.5 7.7e-23 80.2 0.1 3.5 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EER29705.1 - 4.6e-13 48.7 9.1 1e-12 47.5 6.3 1.6 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 EER29705.1 - 0.0087 16.0 6.2 0.019 14.9 4.3 1.5 1 0 0 1 1 1 1 Up-regulated During Septation LON PF02190.11 EER29706.1 - 5.8e-24 84.9 0.0 1e-23 84.0 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 EER29706.1 - 6.2e-10 38.9 25.5 3.1e-07 30.3 10.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER29706.1 - 3.1e-09 36.4 24.2 1.8e-07 30.8 10.0 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_4 PF15227.1 EER29706.1 - 1.1e-08 34.7 24.4 0.00025 20.8 8.8 2.8 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EER29706.1 - 7.8e-08 31.8 23.9 2.5e-07 30.2 9.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EER29706.1 - 1.1e-07 31.4 20.1 2.5e-07 30.2 6.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EER29706.1 - 3.7e-06 26.5 23.1 7e-05 22.4 8.1 2.5 2 0 0 2 2 2 2 zinc-RING finger domain U-box PF04564.10 EER29706.1 - 7.8e-05 22.5 0.1 0.0012 18.7 0.0 2.5 2 0 0 2 2 2 1 U-box domain zf-RING_4 PF14570.1 EER29706.1 - 0.0014 18.2 8.4 0.0014 18.2 5.9 2.0 2 0 0 2 2 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EER29706.1 - 0.0039 16.8 5.8 0.0039 16.8 4.0 3.0 2 1 1 3 3 3 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 EER29706.1 - 0.017 14.8 1.3 0.041 13.5 0.9 1.6 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 EER29706.1 - 0.14 12.2 12.2 0.16 12.1 6.1 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EER29706.1 - 1.8 8.1 13.6 2.8 7.5 0.4 2.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Paf1 PF03985.8 EER29707.1 - 5.7e-37 127.5 0.0 4e-28 98.3 0.0 2.9 2 1 0 2 2 2 2 Paf1 Actin PF00022.14 EER29708.1 - 3.3e-30 104.8 0.0 8.9e-29 100.0 0.0 2.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EER29708.1 - 8.4e-05 21.3 0.0 0.059 11.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2114 PF09887.4 EER29708.1 - 0.089 11.1 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Arf PF00025.16 EER29709.1 - 1.2e-72 242.8 0.0 1.4e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EER29709.1 - 2.9e-11 42.9 0.0 3.6e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EER29709.1 - 2.4e-10 40.0 0.0 2.8e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EER29709.1 - 7.3e-10 38.0 0.4 4.5e-06 25.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EER29709.1 - 7.2e-09 35.1 0.0 8.6e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EER29709.1 - 8.5e-08 32.7 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EER29709.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EER29709.1 - 6.6e-05 22.4 0.0 0.0075 15.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EER29709.1 - 0.0057 15.4 0.1 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 ArgK protein FeoB_N PF02421.13 EER29709.1 - 0.011 14.9 0.5 0.054 12.7 0.3 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 EER29709.1 - 0.084 13.3 0.1 0.19 12.1 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Catalase PF00199.14 EER29710.1 - 2.1e-186 619.2 0.3 2.5e-186 618.9 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EER29710.1 - 2.1e-12 46.6 0.5 5.7e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive MBOAT_2 PF13813.1 EER29711.1 - 4.6e-23 81.0 0.7 4.6e-23 81.0 0.5 2.8 3 1 0 3 3 3 1 Membrane bound O-acyl transferase family Rer1 PF03248.8 EER29712.1 - 3.6e-81 270.9 2.8 4.1e-81 270.7 1.9 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 EER29713.1 - 3.7e-70 235.8 0.1 4.6e-70 235.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EER29713.1 - 0.07 13.2 0.0 0.5 10.5 0.0 2.1 2 1 1 3 3 3 0 2-enoyl-CoA Hydratase C-terminal region A_deaminase PF00962.17 EER29715.1 - 2.4e-39 135.1 0.0 3.6e-39 134.5 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase Acetyltransf_10 PF13673.1 EER29716.1 - 9.8e-10 38.5 0.0 3.6e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EER29716.1 - 5.4e-09 36.0 0.0 8.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EER29716.1 - 2e-05 24.5 0.0 3.3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EER29716.1 - 4.9e-05 23.1 0.0 0.00032 20.5 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EER29716.1 - 0.0044 16.7 0.0 0.0094 15.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein DUF3419 PF11899.3 EER29717.1 - 1.5e-151 504.4 0.0 2.3e-151 503.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_31 PF13847.1 EER29717.1 - 5.4e-05 22.8 0.0 0.00024 20.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EER29717.1 - 8.3e-05 22.5 0.0 0.00044 20.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER29717.1 - 0.099 13.1 0.0 0.41 11.1 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EER29717.1 - 0.16 12.5 0.0 0.52 10.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain FMN_red PF03358.10 EER29718.1 - 1.1e-24 86.7 0.0 1.4e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EER29718.1 - 4.1e-07 29.6 0.0 5.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Lipase_3 PF01764.20 EER29719.1 - 0.00013 21.5 0.0 0.00023 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EER29719.1 - 0.064 13.0 0.1 0.17 11.6 0.1 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family VPS9 PF02204.13 EER29720.1 - 6.2e-24 84.0 0.0 2.1e-23 82.2 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Sel1 PF08238.7 EER29721.1 - 2.4e-18 66.1 7.8 2.6e-06 27.8 0.1 3.6 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.1 EER29721.1 - 0.29 11.8 2.5 0.83 10.4 0.2 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.9 EER29722.1 - 8.5e-49 165.1 11.4 1e-48 164.8 7.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) rve_3 PF13683.1 EER29722.1 - 0.16 11.5 1.1 2.8 7.5 0.0 2.8 3 0 0 3 3 3 0 Integrase core domain PBP_sp32 PF07222.7 EER29722.1 - 0.24 10.5 5.0 0.38 9.9 3.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 CBF PF03914.12 EER29723.1 - 1.4e-49 167.6 0.1 3.6e-48 163.1 0.1 2.5 2 0 0 2 2 2 1 CBF/Mak21 family DRIM PF07539.7 EER29723.1 - 0.012 14.9 0.0 0.047 13.1 0.0 2.1 2 0 0 2 2 2 0 Down-regulated in metastasis Utp12 PF04003.7 EER29723.1 - 0.59 10.0 4.2 0.34 10.8 0.1 2.4 3 0 0 3 3 3 0 Dip2/Utp12 Family GPI-anchored PF10342.4 EER29725.1 - 2.1e-21 76.2 1.0 2.1e-21 76.2 0.7 2.3 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Takusan PF04822.8 EER29726.1 - 8.9 6.1 17.4 0.097 12.4 4.8 2.9 1 1 2 3 3 3 0 Takusan FUSC PF04632.7 EER29726.1 - 9.9 4.4 12.4 12 4.1 8.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family MMS19_C PF12460.3 EER29728.1 - 5.7e-112 374.4 4.1 5.7e-112 374.4 2.8 3.1 2 1 0 3 3 3 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EER29728.1 - 2.1e-93 312.3 1.8 3.1e-92 308.5 0.2 3.1 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.1 EER29728.1 - 1.7e-07 31.5 6.0 0.23 12.0 0.0 7.3 8 0 0 8 8 8 2 HEAT-like repeat HEAT PF02985.17 EER29728.1 - 0.019 15.0 7.8 5.3 7.4 0.0 6.9 7 0 0 7 7 7 0 HEAT repeat HEAT_2 PF13646.1 EER29728.1 - 0.18 12.1 15.1 10 6.5 0.0 6.7 7 1 1 8 8 8 0 HEAT repeats Fasciclin PF02469.17 EER29729.1 - 0.0013 18.7 0.0 0.0031 17.5 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain DUF106 PF01956.11 EER29730.1 - 2.4e-46 157.3 0.1 3.3e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 EER29731.1 - 5.4e-45 152.8 0.0 6.8e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) THF_DHG_CYH PF00763.18 EER29732.1 - 3.9e-18 65.5 0.0 5.5e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EER29732.1 - 9.5e-12 44.2 0.0 8.3e-09 34.7 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ATP-synt_ab PF00006.20 EER29733.1 - 6.9e-71 238.1 0.0 1e-70 237.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EER29733.1 - 1.6e-27 96.2 1.9 4.6e-27 94.7 0.5 2.4 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EER29733.1 - 2.6e-15 56.3 3.1 6.4e-15 55.1 2.1 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EER29733.1 - 0.0047 16.7 1.6 0.0097 15.7 0.8 1.8 2 0 0 2 2 2 1 HAS barrel domain DUF962 PF06127.6 EER29734.1 - 1.6e-19 69.6 4.6 5.4e-19 67.8 3.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) TPT PF03151.11 EER29734.1 - 0.37 10.4 9.0 0.38 10.4 1.1 2.4 1 1 0 2 2 2 0 Triose-phosphate Transporter family SHS2_Rpb7-N PF03876.12 EER29735.1 - 3.2e-14 52.7 0.0 5.3e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EER29735.1 - 6.8e-11 42.1 0.0 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EER29735.1 - 0.084 13.0 0.0 0.22 11.6 0.0 1.6 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 RRM_1 PF00076.17 EER29736.1 - 2.8e-36 122.9 0.1 2.8e-19 68.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29736.1 - 2.2e-29 101.2 0.1 1.2e-16 60.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EER29736.1 - 1.9e-17 62.8 0.0 1.9e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPP_enzyme_N PF02776.13 EER29737.1 - 2.7e-45 153.9 0.2 5.9e-45 152.8 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EER29737.1 - 5.4e-31 107.1 0.0 1.1e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EER29737.1 - 7.4e-18 64.5 0.1 2.6e-17 62.8 0.1 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EER29737.1 - 0.17 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Fungal_trans PF04082.13 EER29738.1 - 5.4e-12 45.1 0.1 1.1e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29738.1 - 1.7e-07 31.0 10.5 3.1e-07 30.1 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSBP1 PF06825.7 EER29738.1 - 0.037 13.6 0.1 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Peptidase_M1 PF01433.15 EER29739.1 - 0.0081 15.2 0.1 3.2 6.7 0.0 3.2 2 1 1 3 3 3 2 Peptidase family M1 LSM PF01423.17 EER29740.1 - 5.8e-14 51.3 0.3 6.4e-14 51.2 0.2 1.0 1 0 0 1 1 1 1 LSM domain PALP PF00291.20 EER29741.1 - 4.8e-51 173.8 0.1 9.9e-51 172.7 0.1 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.4 EER29742.1 - 2.4e-19 68.5 0.5 4.6e-19 67.6 0.4 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 EER29742.1 - 0.073 13.1 0.1 8.7 6.5 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain TPR_1 PF00515.23 EER29743.1 - 9.4e-27 91.4 1.7 1.5e-08 33.8 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EER29743.1 - 1.2e-26 92.1 4.5 9.1e-11 41.2 0.1 4.3 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 EER29743.1 - 2e-24 83.4 1.2 8.8e-07 28.3 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 EER29743.1 - 1.9e-18 65.2 4.8 2.7e-05 24.4 0.2 5.4 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EER29743.1 - 1.3e-16 59.3 2.1 0.0097 16.0 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EER29743.1 - 1.2e-15 57.6 9.7 1.9e-05 25.1 0.0 4.9 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EER29743.1 - 1.7e-14 53.4 6.2 6e-09 35.7 0.3 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EER29743.1 - 2e-14 53.6 3.3 0.0009 19.5 0.0 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EER29743.1 - 4.9e-13 47.8 0.4 7.5e-05 22.2 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER29743.1 - 8.8e-12 43.8 1.6 0.00048 19.7 0.0 5.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_20 PF14561.1 EER29743.1 - 1.9e-09 37.4 3.0 0.0054 16.8 0.0 4.7 3 2 1 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EER29743.1 - 2.1e-07 30.9 1.7 0.00018 21.5 0.2 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EER29743.1 - 1.5e-06 27.9 7.2 0.017 14.9 0.0 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EER29743.1 - 9.6e-06 25.7 3.0 2.4 8.8 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 EER29743.1 - 4.9e-05 23.0 0.0 1.1 9.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EER29743.1 - 9.7e-05 22.1 0.7 0.1 12.5 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EER29743.1 - 0.0006 18.9 0.5 0.8 8.7 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.13 EER29743.1 - 0.035 13.9 4.7 1.2 9.1 0.3 4.4 4 1 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF1641 PF07849.6 EER29743.1 - 0.15 11.7 0.2 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) CDP-OH_P_transf PF01066.16 EER29744.1 - 3.7e-15 56.0 6.0 3.7e-15 56.0 4.2 2.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase BNR PF02012.15 EER29745.1 - 1.3 9.1 3.3 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 BNR/Asp-box repeat Zn_clus PF00172.13 EER29746.1 - 5.7e-06 26.1 10.6 5.7e-06 26.1 7.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EER29746.1 - 0.00026 19.7 1.2 0.0017 17.0 0.9 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3357 PF11837.3 EER29746.1 - 0.044 13.6 0.1 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) ADH_N PF08240.7 EER29747.1 - 6.5e-26 90.2 0.2 1.2e-25 89.3 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER29747.1 - 8.8e-21 73.8 1.1 1.3e-20 73.3 0.8 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EER29747.1 - 2.9e-05 24.9 0.1 4.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELO PF01151.13 EER29748.1 - 4.8e-85 284.8 2.2 6.6e-85 284.3 1.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Per1 PF04080.8 EER29749.1 - 0.0008 18.9 0.6 0.00086 18.8 0.4 1.0 1 0 0 1 1 1 1 Per1-like Spore_YabQ PF09578.5 EER29749.1 - 0.028 14.3 1.4 0.05 13.5 1.0 1.4 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) APH PF01636.18 EER29750.1 - 1.2e-07 31.7 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EER29750.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.15 EER29750.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase CHAP PF05257.11 EER29752.1 - 0.13 11.9 0.6 0.21 11.2 0.1 1.5 2 0 0 2 2 2 0 CHAP domain Hexapep PF00132.19 EER29754.1 - 4e-08 32.4 2.8 0.0013 18.1 0.3 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EER29754.1 - 0.0054 16.8 0.0 0.012 15.6 0.0 1.6 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EER29754.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase Fucokinase PF07959.7 EER29754.1 - 0.028 12.9 1.5 0.13 10.7 0.9 1.9 1 1 1 2 2 2 0 L-fucokinase Spt20 PF12090.3 EER29756.1 - 1.1e-50 171.5 0.2 1.1e-50 171.5 0.2 3.9 3 1 0 3 3 3 1 Spt20 family TruD PF01142.13 EER29757.1 - 2.1e-52 178.1 0.0 2.7e-47 161.2 0.0 3.6 2 1 1 3 3 3 3 tRNA pseudouridine synthase D (TruD) RPE65 PF03055.10 EER29758.1 - 1.9e-119 399.4 0.0 2.2e-119 399.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF2293 PF10056.4 EER29759.1 - 1.5e-28 98.6 0.6 3.1e-28 97.5 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2293) ketoacyl-synt PF00109.21 EER29760.1 - 7.9e-62 209.0 0.0 1.3e-61 208.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EER29760.1 - 1.5e-56 190.9 0.1 6.8e-56 188.7 0.0 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EER29760.1 - 3.4e-51 174.4 0.0 5.4e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EER29760.1 - 1.9e-49 168.4 0.0 3.3e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EER29760.1 - 2e-42 144.9 0.1 1.9e-41 141.7 0.0 2.7 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EER29760.1 - 5.1e-36 123.1 0.1 1.1e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EER29760.1 - 5.4e-22 77.7 0.4 1.5e-21 76.2 0.1 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EER29760.1 - 1.6e-18 66.9 0.0 5.1e-18 65.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EER29760.1 - 1.4e-16 60.6 0.0 3.3e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER29760.1 - 5.7e-13 48.7 0.0 3.9e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER29760.1 - 3.7e-09 36.9 0.0 1.2e-08 35.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER29760.1 - 8.7e-09 35.9 0.0 3.9e-08 33.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EER29760.1 - 8.1e-08 33.2 0.0 3.1e-07 31.3 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EER29760.1 - 1.9e-07 30.7 0.7 4.3e-07 29.6 0.1 1.9 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EER29760.1 - 1e-06 27.9 0.1 2.5e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EER29760.1 - 4e-06 27.1 0.0 1.5e-05 25.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EER29760.1 - 7.4e-06 26.1 0.1 2e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ubie_methyltran PF01209.13 EER29760.1 - 0.00012 21.2 0.0 0.00035 19.7 0.0 1.7 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EER29760.1 - 0.0011 18.9 0.0 0.0081 16.1 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain ACP_syn_III PF08545.5 EER29760.1 - 0.0017 17.9 0.1 0.0048 16.5 0.1 1.8 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PHD PF00628.24 EER29761.1 - 6e-09 35.4 7.6 1e-08 34.7 5.2 1.4 1 0 0 1 1 1 1 PHD-finger DUF1423 PF07227.6 EER29761.1 - 0.58 8.7 2.7 0.89 8.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Peptidase_M35 PF02102.10 EER29762.1 - 1.5e-97 326.5 0.7 1.8e-97 326.2 0.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EER29762.1 - 1.4e-07 32.1 0.1 2.6e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EER29762.1 - 0.0014 18.1 2.4 0.08 12.3 0.3 2.1 2 0 0 2 2 2 2 Putative peptidase family Coagulin PF02035.10 EER29762.1 - 0.051 13.2 0.2 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Coagulin Pkinase PF00069.20 EER29763.1 - 1.3e-37 129.3 0.0 1.8e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29763.1 - 1e-20 73.9 0.0 1.4e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EER29763.1 - 2.8e-05 23.2 0.0 0.0019 17.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FHA PF00498.21 EER29763.1 - 0.12 12.5 0.5 0.37 10.9 0.0 2.1 2 0 0 2 2 2 0 FHA domain YrbL-PhoP_reg PF10707.4 EER29763.1 - 0.17 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Mtc PF03820.12 EER29764.1 - 2.6e-104 348.1 0.0 5.8e-104 347.0 0.0 1.5 1 1 0 1 1 1 1 Tricarboxylate carrier Pkinase PF00069.20 EER29765.1 - 3.4e-54 183.7 0.0 5.5e-54 183.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29765.1 - 2.5e-19 69.3 0.0 8.4e-19 67.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PRCC PF10253.4 EER29765.1 - 0.38 11.4 12.2 0.14 12.8 5.8 2.1 2 1 1 3 3 3 0 Mitotic checkpoint regulator, MAD2B-interacting TAF4 PF05236.9 EER29766.1 - 2.9e-19 69.3 0.1 1.9e-13 50.3 0.3 3.8 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 EER29767.1 - 1e-70 237.4 0.0 8e-68 228.0 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EER29767.1 - 3e-32 111.2 0.0 6.6e-32 110.1 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EER29767.1 - 5.1e-18 65.4 0.1 8.9e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EER29767.1 - 3.8e-11 42.9 0.2 6.7e-11 42.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EER29767.1 - 5.1e-08 32.6 0.2 9.5e-08 31.7 0.2 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EER29767.1 - 5.8e-05 22.8 0.1 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BSP_II PF05432.6 EER29767.1 - 0.081 12.1 1.6 0.18 11.0 1.1 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sugar_tr PF00083.19 EER29768.1 - 1.4e-77 261.2 22.3 1.7e-77 260.9 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EER29768.1 - 3.3e-30 105.0 54.0 4.5e-26 91.3 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EER29768.1 - 0.00067 18.1 2.0 0.00067 18.1 1.4 3.5 2 2 2 4 4 4 2 MFS/sugar transport protein TRI12 PF06609.8 EER29768.1 - 0.052 11.7 12.9 0.007 14.6 2.1 2.2 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Aminotran_3 PF00202.16 EER29769.1 - 1.4e-86 290.4 0.0 1.8e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III FYVE PF01363.16 EER29770.1 - 2.7e-14 52.7 7.8 4.3e-14 52.1 5.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EER29770.1 - 0.65 9.9 14.8 0.28 11.1 6.9 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger IBR PF01485.16 EER29770.1 - 0.68 9.8 7.2 0.055 13.3 1.4 1.7 2 0 0 2 2 2 0 IBR domain BTB_2 PF02214.17 EER29771.1 - 1.9e-09 37.5 0.1 3.8e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 EER29771.1 - 0.0012 18.8 0.0 0.066 13.2 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain YobH PF13996.1 EER29771.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 YobH-like protein GST_C_3 PF14497.1 EER29772.1 - 3.2e-07 30.7 0.0 5.3e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EER29772.1 - 6.5e-07 29.2 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EER29772.1 - 1.4e-06 28.3 0.0 2.7e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EER29772.1 - 1.4e-06 28.0 0.0 3.3e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EER29772.1 - 8.8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EER29772.1 - 1.6e-05 25.0 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NKAIN PF05640.9 EER29772.1 - 0.096 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein NDUF_B4 PF07225.7 EER29773.1 - 7.7e-05 22.5 0.0 8.9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SAP18 PF06487.7 EER29774.1 - 4.1e-44 149.2 0.0 5.3e-44 148.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Pyr_redox_3 PF13738.1 EER29775.1 - 3.6e-09 36.9 0.0 1.6e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EER29775.1 - 0.0096 14.8 0.0 0.2 10.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Arf PF00025.16 EER29776.1 - 9.9e-39 132.3 0.1 6e-26 90.7 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EER29776.1 - 1.2e-12 47.2 0.0 3.9e-06 25.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EER29776.1 - 2.1e-07 31.4 0.0 2.6e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EER29776.1 - 7.9e-07 28.6 0.0 0.00083 18.7 0.0 2.6 2 1 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 EER29776.1 - 2e-06 27.1 0.0 2.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EER29776.1 - 2.1e-06 27.6 0.0 9.5e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EER29776.1 - 3.2e-06 26.5 0.0 1.9e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EER29776.1 - 2.4e-05 23.8 0.0 0.00066 19.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EER29776.1 - 0.062 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EER29776.1 - 0.11 11.8 0.2 0.26 10.5 0.1 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PIGA PF08288.7 EER29777.1 - 1.5e-46 156.7 4.7 1.7e-46 156.4 1.6 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EER29777.1 - 8.3e-30 103.4 0.0 1.2e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EER29777.1 - 2.5e-17 63.3 0.0 4.4e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EER29777.1 - 2.1e-16 60.1 0.7 4.2e-16 59.1 0.5 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EER29777.1 - 8.4e-16 58.5 0.0 1.6e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EER29777.1 - 1.9e-06 27.7 0.4 3.4e-06 26.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EER29777.1 - 0.00076 19.7 0.0 0.0019 18.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DEAD PF00270.24 EER29778.1 - 4.7e-35 120.5 1.6 1.6e-16 60.3 0.0 2.5 2 1 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EER29778.1 - 6.1e-19 67.6 0.1 1.2e-18 66.7 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER29778.1 - 1.1e-06 28.5 0.0 3.4e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Kelch_5 PF13854.1 EER29780.1 - 4.1e-21 74.5 1.9 2.7e-16 59.1 0.8 4.4 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.1 EER29780.1 - 4.9e-07 29.7 8.7 0.0005 20.1 0.0 5.6 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EER29780.1 - 8.6e-06 25.4 2.6 0.0034 17.1 0.0 4.2 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.10 EER29780.1 - 2.1e-05 24.0 0.7 0.021 14.5 0.1 3.8 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 EER29780.1 - 8.8e-05 21.9 4.6 0.032 13.7 0.2 4.1 3 1 0 3 3 3 1 Kelch motif Kelch_6 PF13964.1 EER29780.1 - 0.00028 20.9 4.0 0.0088 16.1 0.1 4.1 5 0 0 5 5 5 1 Kelch motif PetG PF02529.10 EER29780.1 - 0.02 14.4 0.3 0.052 13.0 0.2 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit 5 DUF4381 PF14316.1 EER29780.1 - 0.51 10.4 1.3 0.8 9.7 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Thiolase_C PF02803.13 EER29781.1 - 4.4e-11 42.2 0.3 4.5e-10 39.0 0.3 2.4 1 1 1 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EER29781.1 - 2.5e-06 27.1 0.4 7.6e-06 25.5 0.3 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EER29781.1 - 2.6e-06 26.6 0.2 0.00058 18.9 0.0 2.5 3 0 0 3 3 3 2 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EER29781.1 - 3.3e-05 23.4 1.7 0.0025 17.4 0.1 2.8 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GMC_oxred_N PF00732.14 EER29782.1 - 1.8e-44 152.0 0.3 2.8e-44 151.4 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EER29782.1 - 2.9e-28 98.9 0.1 2.6e-27 95.8 0.0 2.2 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.9 EER29782.1 - 1.1e-05 25.4 0.3 0.00077 19.3 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EER29782.1 - 0.00012 21.0 2.4 0.00013 20.9 0.9 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EER29782.1 - 0.0003 19.9 0.1 0.0009 18.3 0.1 1.7 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EER29782.1 - 0.0006 18.8 3.5 0.0011 17.8 2.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER29782.1 - 0.00097 19.1 0.5 0.0034 17.3 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EER29782.1 - 0.002 17.2 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FA_hydroxylase PF04116.8 EER29784.1 - 2e-18 66.8 10.2 2e-18 66.8 7.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RHH_1 PF01402.16 EER29784.1 - 0.11 12.4 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family TCTP PF00838.12 EER29785.1 - 6e-44 149.9 0.2 7.9e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Translationally controlled tumour protein FliE PF02049.13 EER29785.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Flagellar hook-basal body complex protein FliE SRP19 PF01922.12 EER29786.1 - 4.7e-29 100.8 0.0 6.8e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Fungal_trans PF04082.13 EER29787.1 - 3.1e-15 55.7 0.0 7.3e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29787.1 - 4.4e-11 42.5 8.0 8.1e-11 41.6 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.23 EER29789.1 - 1.1e-06 28.1 0.6 1.9e-06 27.3 0.4 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EER29789.1 - 0.0064 16.3 0.0 0.018 14.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF1814 PF08843.6 EER29791.1 - 4.2e-09 36.5 0.0 5e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF2204 PF09970.4 EER29791.1 - 0.12 11.8 0.0 1.4 8.3 0.0 2.1 2 0 0 2 2 2 0 Nucleotidyl transferase of unknown function (DUF2204) Pkinase PF00069.20 EER29792.1 - 2.3e-13 49.9 0.0 1.2e-12 47.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29792.1 - 1.4e-12 47.2 0.0 2.1e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EER29792.1 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EER29792.1 - 0.00037 20.3 0.0 0.00088 19.0 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EER29792.1 - 0.0078 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EER29794.1 - 2.2e-15 57.0 0.1 7.4e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EER29794.1 - 0.0023 16.6 0.0 0.18 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Kdo PF06293.9 EER29794.1 - 0.036 13.1 0.0 2.2 7.3 0.0 2.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family p450 PF00067.17 EER29795.1 - 3.6e-57 193.8 0.0 4.8e-57 193.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EER29796.1 - 1.7e-18 66.8 0.0 2.7e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EER29796.1 - 2.1e-08 34.7 0.0 2.4e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EER29796.1 - 4.4e-06 26.3 0.0 2.5e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EER29796.1 - 4.5e-05 23.8 0.0 0.00012 22.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EER29796.1 - 5.7e-05 23.5 0.0 0.00041 20.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EER29796.1 - 0.00062 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EER29796.1 - 0.001 18.4 0.0 0.0038 16.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EER29796.1 - 0.015 14.3 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 EER29796.1 - 0.018 15.3 0.0 0.056 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EER29796.1 - 0.033 14.2 0.0 0.28 11.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain CSTF_C PF14304.1 EER29796.1 - 0.06 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal FtsJ PF01728.14 EER29796.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EER29796.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Thioesterase PF00975.15 EER29797.1 - 1.3e-18 68.0 0.0 1.8e-17 64.3 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EER29797.1 - 1.4e-07 31.6 0.0 1.9e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER29797.1 - 2.2e-05 24.2 0.0 3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EER29797.1 - 0.0056 16.1 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EER29797.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EER29797.1 - 0.091 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF1125 PF06563.6 EER29798.1 - 0.022 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1125) p450 PF00067.17 EER29799.1 - 1.8e-10 39.9 0.0 2.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EER29800.1 - 9.1e-26 90.3 40.5 2.2e-25 89.1 28.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EER29800.1 - 1.6e-06 26.9 8.9 1.6e-06 26.9 6.2 2.4 1 1 1 2 2 2 2 Sugar (and other) transporter HisKA PF00512.20 EER29801.1 - 0.028 14.3 1.8 1.1 9.2 0.8 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain OrfB_Zn_ribbon PF07282.6 EER29801.1 - 0.12 12.0 1.3 0.41 10.3 0.9 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain AA_permease PF00324.16 EER29802.1 - 2.1e-138 461.6 40.5 2.4e-138 461.4 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EER29802.1 - 8.1e-40 136.6 42.6 9.8e-40 136.3 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_4 PF01063.14 EER29803.1 - 4.2e-20 72.1 0.0 5.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Cytokin_check_N PF10407.4 EER29804.1 - 9.2e-06 25.1 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Ribonuc_2-5A PF06479.7 EER29805.1 - 1.5e-42 144.4 0.0 2.4e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EER29805.1 - 4.3e-42 144.0 0.0 6.4e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29805.1 - 1.8e-20 73.1 0.0 6.2e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 EER29805.1 - 0.0018 17.6 0.1 0.38 10.3 0.0 3.2 3 0 0 3 3 3 1 PQQ enzyme repeat Kdo PF06293.9 EER29805.1 - 0.011 14.7 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EER29805.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pro_isomerase PF00160.16 EER29806.1 - 2.1e-50 170.9 0.1 4.3e-50 169.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EER29806.1 - 2.5e-13 49.3 1.6 2.5e-05 23.9 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 EER29807.1 - 9e-133 443.4 10.0 1.1e-132 443.1 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 EER29807.1 - 0.18 11.9 1.4 0.7 10.0 0.1 2.5 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Pkinase PF00069.20 EER29808.1 - 6.1e-10 38.6 0.0 9.2e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29808.1 - 9.1e-06 24.9 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EER29809.1 - 4.7e-27 94.7 0.0 1.2e-26 93.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29809.1 - 1.6e-11 43.7 0.0 2.6e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF3439 PF11921.3 EER29810.1 - 0.0047 16.6 3.1 0.0047 16.6 2.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Rtf2 PF04641.7 EER29810.1 - 0.0092 15.2 5.0 0.012 14.8 3.4 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger FLO_LFY PF01698.11 EER29810.1 - 0.011 14.6 1.9 0.012 14.5 1.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Otopetrin PF03189.8 EER29810.1 - 0.049 12.6 0.2 0.063 12.2 0.1 1.1 1 0 0 1 1 1 0 Otopetrin Nuc_recep-AF1 PF11825.3 EER29810.1 - 0.14 12.1 1.4 0.19 11.6 1.0 1.2 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 Eapp_C PF10238.4 EER29810.1 - 0.16 11.8 7.9 0.23 11.3 5.5 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein S-antigen PF05756.6 EER29810.1 - 0.22 11.5 7.4 0.29 11.1 5.1 1.2 1 0 0 1 1 1 0 S-antigen protein OAD_gamma PF04277.8 EER29810.1 - 1.5 9.2 3.6 2.4 8.5 2.5 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.5 EER29810.1 - 2.4 7.9 10.5 3.3 7.4 7.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2457 PF10446.4 EER29810.1 - 3.5 6.2 16.4 4.5 5.8 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Acetyltransf_1 PF00583.19 EER29811.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EER29811.1 - 0.0024 18.0 0.0 0.0046 17.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EER29811.1 - 0.087 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EER29811.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pam17 PF08566.5 EER29814.1 - 2.2e-71 239.1 0.1 3.9e-71 238.3 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Peptidase_S64 PF08192.6 EER29814.1 - 5.6 5.1 7.4 7.3 4.7 5.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Far-17a_AIG1 PF04750.9 EER29815.1 - 3.3e-52 176.5 5.7 3.7e-52 176.4 3.9 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3602 PF12223.3 EER29816.1 - 8.4e-15 54.9 16.2 3.3e-13 49.7 0.6 4.1 2 1 2 4 4 4 3 Protein of unknown function (DUF3602) VacA2 PF03077.9 EER29816.1 - 0.07 12.7 0.3 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Putative vacuolating cytotoxin Fungal_trans_2 PF11951.3 EER29817.1 - 2.9e-33 115.0 0.1 4.6e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain eIF-4B PF06273.6 EER29817.1 - 0.011 14.5 4.9 0.018 13.8 3.4 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Zn_clus PF00172.13 EER29817.1 - 0.05 13.5 1.7 0.11 12.4 1.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Velvet PF11754.3 EER29818.1 - 7.3e-79 264.0 0.0 9.1e-79 263.7 0.0 1.1 1 0 0 1 1 1 1 Velvet factor NmrA PF05368.8 EER29819.1 - 1.4e-10 40.8 0.0 1.9e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EER29819.1 - 8.4e-08 32.4 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EER29819.1 - 0.0037 17.1 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER29819.1 - 0.02 14.5 0.0 0.056 13.1 0.0 1.7 1 0 0 1 1 1 0 KR domain DLH PF01738.13 EER29820.1 - 7.6e-30 103.8 0.0 8.6e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EER29820.1 - 7.8e-10 38.6 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EER29820.1 - 0.00012 22.0 0.0 0.0045 16.8 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER29820.1 - 0.025 14.1 0.0 0.087 12.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 EER29820.1 - 0.06 13.0 0.0 1.7 8.2 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4224 PF13986.1 EER29820.1 - 0.096 12.2 0.1 1.1 8.8 0.1 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4224) SWIB PF02201.13 EER29821.1 - 5.3e-21 74.0 0.0 8.2e-21 73.4 0.0 1.3 1 0 0 1 1 1 1 SWIB/MDM2 domain eIF2A PF08662.6 EER29822.1 - 5.3e-39 133.9 4.4 5.8e-37 127.3 0.7 4.0 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RRM_5 PF13893.1 EER29822.1 - 7.2e-07 28.9 0.0 2.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EER29822.1 - 1.8e-06 27.4 0.0 4.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EER29822.1 - 2.3e-05 24.2 0.0 9.2e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EER29822.1 - 0.00019 21.1 0.1 0.064 13.1 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Glyoxalase_2 PF12681.2 EER29823.1 - 2.7e-06 27.9 0.0 3.6e-06 27.5 0.0 1.3 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EER29823.1 - 0.00098 19.1 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peptidase_S10 PF00450.17 EER29824.1 - 3.9e-120 401.8 0.0 4.7e-120 401.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EER29824.1 - 0.0011 18.8 0.0 0.0046 16.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.13 EER29825.1 - 6.9e-11 41.5 2.1 4.1e-10 38.9 0.5 2.5 2 1 1 3 3 3 1 Fungal specific transcription factor domain DUF221 PF02714.10 EER29827.1 - 1.2e-106 356.2 21.7 1.8e-106 355.6 15.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EER29827.1 - 1.1e-29 102.1 0.1 2.8e-29 100.8 0.1 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EER29827.1 - 3.3e-17 62.7 0.1 7.8e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 EER29827.1 - 2.3e-13 50.0 0.5 2.3e-13 50.0 0.3 2.5 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport zf-C3HC4_3 PF13920.1 EER29828.1 - 1.4e-05 24.7 9.8 1.4e-05 24.7 6.8 3.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.16 EER29829.1 - 1.3e-76 257.1 0.5 1.9e-76 256.5 0.3 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EER29829.1 - 5.4e-30 104.7 3.4 5.4e-30 104.7 2.4 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EER29829.1 - 2.3e-11 43.6 2.4 3.5e-11 43.1 0.2 2.4 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 EER29829.1 - 1.1e-10 41.7 0.3 3.6e-10 40.0 0.2 1.9 1 0 0 1 1 1 1 MutS domain II WD40 PF00400.27 EER29830.1 - 2e-84 274.7 24.3 7.6e-15 54.1 0.5 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EER29830.1 - 8.4e-09 35.4 0.0 0.021 14.5 0.0 3.9 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EER29830.1 - 1.3e-07 30.1 9.3 0.16 10.0 0.1 5.4 3 3 1 5 5 5 4 Nucleoporin Nup120/160 NLE PF08154.7 EER29830.1 - 5.1e-06 26.3 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EER29830.1 - 0.0052 16.7 0.1 0.25 11.3 0.0 2.7 2 1 0 2 2 2 1 Siderophore-interacting FAD-binding domain TFIIIC_delta PF12657.2 EER29830.1 - 0.0099 15.6 1.8 2.3 7.9 0.0 3.8 3 1 1 4 4 4 1 Transcription factor IIIC subunit delta N-term CAP PF00188.21 EER29831.1 - 3.3e-18 66.3 2.7 4.6e-18 65.8 1.9 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sec10 PF07393.6 EER29832.1 - 1.1e-166 556.0 4.7 1.4e-166 555.7 3.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EER29832.1 - 0.0008 19.0 0.0 0.0018 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EER29832.1 - 0.0018 17.8 0.4 0.0059 16.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain Vps53_N PF04100.7 EER29832.1 - 0.021 13.6 0.0 1.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Vps53-like, N-terminal AAA PF00004.24 EER29833.1 - 1.4e-21 77.0 0.0 2.2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Cytochrom_C1 PF02167.10 EER29834.1 - 1.1e-79 267.1 0.0 1.4e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EER29834.1 - 0.017 15.2 0.0 0.039 14.0 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III AIG2_2 PF13772.1 EER29835.1 - 4.9e-05 23.3 0.1 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.15 EER29837.1 - 3.9e-101 337.3 0.0 4.7e-101 337.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family DUF221 PF02714.10 EER29838.1 - 3.8e-100 334.9 19.8 3.8e-100 334.9 13.8 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EER29838.1 - 2.7e-43 147.2 1.3 2.7e-43 147.2 0.9 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EER29838.1 - 1.3e-24 86.5 0.4 2.3e-24 85.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Anoctamin PF04547.7 EER29838.1 - 0.00029 19.6 3.4 0.00074 18.2 0.7 2.4 2 0 0 2 2 2 1 Calcium-activated chloride channel RRM_6 PF14259.1 EER29838.1 - 0.0012 18.7 0.0 0.87 9.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-DHHC PF01529.15 EER29838.1 - 8.2 5.7 10.5 0.34 10.2 0.1 3.2 3 1 1 4 4 4 0 DHHC palmitoyltransferase hDGE_amylase PF14701.1 EER29839.1 - 4.8e-176 585.8 0.0 6.3e-176 585.4 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EER29839.1 - 7.4e-119 396.7 0.2 2e-118 395.3 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EER29839.1 - 1.3e-85 286.7 0.0 2e-85 286.0 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme Alpha-amylase PF00128.19 EER29839.1 - 1.1e-05 24.9 0.0 0.0057 16.1 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain SLX9 PF15341.1 EER29840.1 - 3e-39 134.2 7.0 4.2e-39 133.7 4.8 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 NAD_Gly3P_dh_C PF07479.9 EER29841.1 - 2.6e-43 147.2 0.2 4.2e-43 146.6 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EER29841.1 - 4.7e-39 133.6 0.0 1.8e-38 131.7 0.0 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EER29842.1 - 4.4e-42 143.1 0.0 8.4e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EER29842.1 - 9.7e-22 76.3 0.1 1.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EER29842.1 - 1.2e-12 48.1 0.0 2.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EER29842.1 - 0.00057 20.0 0.1 0.0033 17.5 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EER29842.1 - 0.015 14.7 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EER29842.1 - 0.036 14.3 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EER29842.1 - 0.036 13.1 1.1 0.094 11.7 0.8 1.7 1 0 0 1 1 1 0 FAD binding domain ChlamPMP_M PF07548.6 EER29842.1 - 0.085 12.5 0.0 0.085 12.5 0.0 2.0 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein middle domain DAO PF01266.19 EER29842.1 - 0.09 11.6 0.1 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DPBB_1 PF03330.13 EER29843.1 - 2.1e-09 37.2 0.1 4.1e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EER29843.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Barwin family ETRAMP PF09716.5 EER29843.1 - 0.46 10.4 2.0 0.67 9.9 0.8 1.7 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DELLA PF12041.3 EER29845.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal DLH PF01738.13 EER29846.1 - 1.7e-11 43.8 0.0 2.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EER29846.1 - 2.6e-05 23.9 0.0 3.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EER29847.1 - 6.9e-08 32.2 6.5 1e-07 31.7 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.22 EER29848.1 - 1.3e-16 59.6 1.3 2.3e-16 58.8 0.9 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EER29848.1 - 0.022 14.3 3.5 0.039 13.5 2.4 1.4 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) zf-C2H2 PF00096.21 EER29849.1 - 4.1e-11 42.5 14.3 6.6e-06 26.1 2.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EER29849.1 - 3.9e-09 36.2 9.6 8.3e-05 22.6 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EER29849.1 - 6.2e-07 29.4 14.9 1.2e-05 25.3 2.9 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EER29849.1 - 5.4e-05 23.2 3.1 0.01 15.9 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EER29849.1 - 0.00094 19.2 8.3 0.015 15.4 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-BED PF02892.10 EER29849.1 - 0.0022 17.7 1.1 0.055 13.2 0.2 2.5 2 0 0 2 2 2 1 BED zinc finger zf-met PF12874.2 EER29849.1 - 0.0023 18.0 4.4 0.75 10.0 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EER29849.1 - 0.19 11.7 4.2 1.5 8.8 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Dynamin_N PF00350.18 EER29850.1 - 8.1e-29 100.5 0.0 1.7e-28 99.5 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EER29850.1 - 4.7e-21 74.8 0.0 1.4e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EER29850.1 - 0.00045 20.0 0.6 0.00045 20.0 0.4 2.9 4 0 0 4 4 4 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EER29850.1 - 0.00046 20.1 0.0 0.0025 17.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 EER29850.1 - 0.0011 18.9 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EER29850.1 - 0.0081 16.6 0.1 0.15 12.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EER29850.1 - 0.023 14.2 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1151 PF06625.6 EER29850.1 - 0.089 12.5 1.1 1.6 8.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Nucleoporin_FG PF13634.1 EER29850.1 - 0.87 9.8 29.0 0.026 14.7 5.1 2.4 1 1 1 2 2 2 0 Nucleoporin FG repeat region Transp_cyt_pur PF02133.10 EER29851.1 - 7.5e-103 344.4 31.2 8.9e-103 344.1 21.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2568 PF10823.3 EER29851.1 - 4.1 7.6 14.4 4.2 7.6 7.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2568) DUF917 PF06032.7 EER29852.1 - 1.1e-109 366.2 0.3 3.1e-109 364.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EER29852.1 - 3.1e-53 180.7 6.7 8.9e-51 172.6 2.0 2.8 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EER29852.1 - 3.1e-29 101.7 2.9 4.7e-28 97.8 0.0 3.2 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EER29852.1 - 5.5e-05 21.6 2.3 0.023 13.0 0.3 3.2 3 0 0 3 3 3 2 MutL protein BcrAD_BadFG PF01869.15 EER29852.1 - 0.0057 15.9 1.6 0.015 14.6 0.1 2.4 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Pyridoxal_deC PF00282.14 EER29853.1 - 1.4e-59 201.4 0.0 2e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EER29853.1 - 0.0011 17.8 0.0 0.0017 17.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Fungal_trans_2 PF11951.3 EER29854.1 - 1.8e-57 194.7 0.2 2.2e-57 194.4 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29854.1 - 9.2e-07 28.6 12.8 1.7e-06 27.8 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 EER29855.1 - 1.9e-15 56.1 3.1 3e-15 55.5 2.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) EutQ PF06249.7 EER29856.1 - 5.9e-13 48.6 0.0 6.5e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EER29856.1 - 1.1e-08 34.3 0.0 1.6e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EER29856.1 - 1.3e-05 24.5 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EER29856.1 - 0.01 15.4 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 Cupin Pirin PF02678.11 EER29856.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Pirin Pkinase PF00069.20 EER29857.1 - 1.2e-55 188.5 0.1 7.1e-55 185.9 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29857.1 - 3.1e-29 101.8 0.6 5.5e-21 74.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EER29857.1 - 4e-06 26.0 0.1 3.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 EER29857.1 - 8.5e-06 26.2 0.1 1.9e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EER29857.1 - 0.00038 20.2 5.1 0.11 12.2 0.0 3.4 1 1 2 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EER29857.1 - 0.033 13.2 0.0 0.089 11.8 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DIRP PF06584.8 EER29857.1 - 0.79 9.6 4.3 1.8 8.4 0.1 3.0 3 0 0 3 3 3 0 DIRP DUF1687 PF07955.6 EER29858.1 - 1.7e-12 47.4 0.4 5.5e-11 42.5 0.3 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) UbiA PF01040.13 EER29859.1 - 6.6 5.8 15.5 8.8 5.4 10.7 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family TM_helix PF05552.7 EER29859.1 - 9 6.0 10.2 0.58 9.8 3.6 1.6 2 0 0 2 2 2 0 Conserved TM helix Glyco_transf_8 PF01501.15 EER29860.1 - 0.0043 16.4 2.3 0.53 9.5 1.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EER29860.1 - 0.04 13.2 0.1 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Fungal_trans PF04082.13 EER29861.1 - 5.9e-24 84.3 7.4 1.2e-23 83.3 5.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER29861.1 - 6.1e-06 26.0 8.6 6.1e-06 26.0 6.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2427 PF10348.4 EER29861.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Oxidored_q6 PF01058.17 EER29862.1 - 5.3e-23 81.0 0.0 6.9e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Abhydrolase_2 PF02230.11 EER29864.1 - 7.3e-59 198.8 0.0 2.2e-58 197.2 0.0 1.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EER29864.1 - 3.5e-10 39.8 0.0 6.1e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EER29864.1 - 2.6e-07 30.4 0.0 0.00094 18.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EER29864.1 - 8.1e-07 29.1 0.0 0.0068 16.3 0.0 2.5 2 1 1 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EER29864.1 - 2.6e-06 26.7 0.1 0.00033 19.9 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 EER29864.1 - 0.00027 20.3 0.0 0.00047 19.5 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 EER29864.1 - 0.00035 20.0 0.0 0.00055 19.4 0.0 1.3 1 1 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.9 EER29864.1 - 0.0082 15.3 0.0 0.042 13.0 0.0 1.9 2 0 0 2 2 2 1 Secretory lipase Esterase PF00756.15 EER29864.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EER29864.1 - 0.046 13.3 0.0 0.09 12.3 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Ctr PF04145.10 EER29866.1 - 1.8e-33 115.6 0.4 2e-33 115.4 0.3 1.0 1 0 0 1 1 1 1 Ctr copper transporter family FAD_binding_8 PF08022.7 EER29867.1 - 1.6e-18 66.5 0.0 3e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EER29867.1 - 1.5e-17 63.9 0.0 2.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EER29867.1 - 1.1e-14 54.6 10.9 1.1e-14 54.6 7.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EER29867.1 - 0.022 14.8 0.0 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain adh_short PF00106.20 EER29868.1 - 3.1e-18 66.2 0.8 1.1e-16 61.2 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER29868.1 - 2.3e-09 37.1 0.0 4.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EER29868.1 - 0.0053 15.7 0.0 0.066 12.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EER29868.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EER29868.1 - 0.044 13.2 0.0 0.27 10.6 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EER29868.1 - 0.062 12.6 0.0 3.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family NAC PF01849.13 EER29869.1 - 1.9e-22 78.5 0.4 3.3e-22 77.7 0.3 1.4 1 0 0 1 1 1 1 NAC domain Nup35_RRM PF05172.8 EER29870.1 - 0.041 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif His_Phos_2 PF00328.17 EER29871.1 - 6.9e-35 120.9 0.0 7.9e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) FAD_binding_3 PF01494.14 EER29872.1 - 4.3e-72 243.1 0.0 2.3e-71 240.7 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EER29872.1 - 2.2e-27 95.7 0.0 3.9e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EER29872.1 - 0.026 13.4 0.9 0.83 8.4 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EER29872.1 - 0.052 12.1 0.0 0.089 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase SE PF08491.5 EER29872.1 - 0.073 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.9 EER29872.1 - 0.074 11.5 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EER29872.1 - 0.075 12.8 0.0 0.51 10.1 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-C2H2 PF00096.21 EER29873.1 - 1.9e-08 34.1 13.8 0.00075 19.6 2.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER29873.1 - 2.5e-06 27.4 0.9 2.5e-06 27.4 0.6 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER29873.1 - 0.00076 19.6 16.2 0.013 15.8 1.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EER29873.1 - 0.034 14.3 3.6 0.067 13.4 1.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EER29873.1 - 0.046 13.4 10.0 0.34 10.7 2.0 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_jaz PF12171.3 EER29873.1 - 3.4 7.9 6.1 4.1 7.6 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding BTB PF00651.26 EER29874.1 - 8.4e-31 106.2 0.4 5.4e-17 61.7 0.2 2.8 3 0 0 3 3 3 2 BTB/POZ domain Ank PF00023.25 EER29874.1 - 1.6e-08 33.9 0.3 1.1e-05 24.9 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EER29874.1 - 2.5e-08 34.1 0.1 6.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER29874.1 - 3.6e-07 30.5 0.0 1.2e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EER29874.1 - 1.2e-05 25.4 0.1 0.00011 22.2 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER29874.1 - 0.0024 17.9 0.2 0.046 13.9 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat YqzH PF14164.1 EER29874.1 - 0.027 14.3 0.4 25 4.8 0.1 3.5 3 0 0 3 3 3 0 YqzH-like protein Pkinase PF00069.20 EER29875.1 - 3.4e-59 200.1 0.0 5.2e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29875.1 - 1.2e-35 122.8 0.0 8.5e-24 84.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase UPF0731 PF14982.1 EER29875.1 - 0.003 17.4 3.2 0.15 12.0 0.7 2.6 2 0 0 2 2 2 1 UPF0731 family APH PF01636.18 EER29875.1 - 0.0035 17.0 0.4 0.037 13.7 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EER29875.1 - 0.011 14.7 0.0 0.035 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DUF99 PF01949.11 EER29875.1 - 0.15 11.1 0.1 0.3 10.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 Wbp11 PF09429.5 EER29878.1 - 2.6e-24 85.0 16.5 3.3e-24 84.6 10.3 2.0 2 0 0 2 2 2 1 WW domain binding protein 11 DUF2365 PF10157.4 EER29879.1 - 0.0016 18.3 0.2 0.0019 18.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) BLOC1_2 PF10046.4 EER29879.1 - 0.0069 16.5 0.5 0.045 13.8 0.2 2.0 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DEAD PF00270.24 EER29880.1 - 6.4e-36 123.3 0.1 1.1e-35 122.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER29880.1 - 9.1e-25 86.3 0.0 1.6e-23 82.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER29880.1 - 5.6e-06 26.3 0.1 1.5e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EER29880.1 - 0.0027 16.8 0.0 0.017 14.2 0.0 2.0 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Lipase_3 PF01764.20 EER29881.1 - 4.7e-16 58.6 0.0 1.2e-15 57.3 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EER29881.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family APH PF01636.18 EER29882.1 - 3.2e-16 59.7 0.0 6e-15 55.6 0.0 2.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EER29882.1 - 0.00086 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EER29882.1 - 0.015 14.3 0.0 0.076 11.9 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase DUF3469 PF11952.3 EER29882.1 - 0.057 13.1 0.2 0.17 11.5 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3469) Pkinase PF00069.20 EER29883.1 - 5.4e-19 68.3 0.0 9.7e-18 64.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29883.1 - 6.4e-08 31.9 0.0 1.2e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EER29883.1 - 0.027 14.2 0.0 0.065 12.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family APH PF01636.18 EER29885.1 - 2.8e-13 50.1 0.0 5.4e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EER29885.1 - 0.0002 21.0 0.1 0.00044 19.8 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase He_PIG_assoc PF10632.4 EER29885.1 - 0.41 10.0 1.8 0.87 8.9 1.3 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase DASH_Hsk3 PF08227.6 EER29887.1 - 6.8e-19 67.7 0.4 9.1e-19 67.3 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like FTA4 PF13093.1 EER29887.1 - 0.11 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Gon7 PF08738.5 EER29887.1 - 0.15 12.0 0.5 0.21 11.5 0.4 1.1 1 0 0 1 1 1 0 Gon7 family FlxA PF14282.1 EER29887.1 - 0.15 11.9 1.1 0.23 11.4 0.8 1.2 1 0 0 1 1 1 0 FlxA-like protein HCV_NS5a_C PF12941.2 EER29887.1 - 0.48 9.9 3.8 0.58 9.6 2.6 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region ApbA PF02558.11 EER29888.1 - 9.1e-25 86.8 0.0 1.6e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EER29888.1 - 6e-21 74.7 0.0 9.8e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal SMC_N PF02463.14 EER29889.1 - 1.6e-22 79.8 0.0 2.6e-22 79.1 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EER29889.1 - 8.3e-11 42.5 30.0 8.3e-11 42.5 20.8 5.4 2 2 1 3 3 2 1 AAA domain AAA_21 PF13304.1 EER29889.1 - 5.6e-07 29.8 0.3 0.00081 19.4 0.0 3.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EER29889.1 - 5.1e-05 22.7 0.0 0.00012 21.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Baculo_PEP_C PF04513.7 EER29889.1 - 6.7e-05 22.7 7.0 2.9 7.7 0.1 4.6 4 0 0 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EER29889.1 - 0.0004 19.6 2.3 1.3 8.1 0.0 4.3 2 1 3 5 5 5 1 Reovirus sigma C capsid protein AAA_25 PF13481.1 EER29889.1 - 0.0071 15.7 0.8 0.031 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Nup54 PF13874.1 EER29889.1 - 0.009 15.6 1.2 0.009 15.6 0.8 7.2 3 2 2 7 7 6 1 Nucleoporin complex subunit 54 AAA_19 PF13245.1 EER29889.1 - 0.016 14.9 2.0 0.02 14.6 0.1 2.2 2 0 0 2 2 1 0 Part of AAA domain NACHT PF05729.7 EER29889.1 - 0.021 14.5 0.1 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 EER29889.1 - 0.024 13.1 69.3 0.02 13.3 12.1 5.2 3 2 1 4 4 3 0 AAA domain ABC_tran PF00005.22 EER29889.1 - 0.047 13.9 0.0 0.047 13.9 0.0 4.0 3 2 0 3 3 2 0 ABC transporter AAA_22 PF13401.1 EER29889.1 - 0.06 13.5 0.0 0.31 11.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EER29889.1 - 0.17 12.0 1.6 0.72 10.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EER29889.1 - 0.32 10.9 0.0 0.32 10.9 0.0 4.5 3 1 1 4 4 4 0 AAA ATPase domain IncA PF04156.9 EER29889.1 - 0.42 10.1 83.9 0.052 13.1 12.5 5.9 3 2 3 6 6 6 0 IncA protein Myosin_tail_1 PF01576.14 EER29889.1 - 1.8 6.1 95.0 0.024 12.3 13.6 3.2 2 1 1 3 3 3 0 Myosin tail AdoMet_MTase PF07757.8 EER29890.1 - 2.9e-38 130.4 0.4 1.9e-37 127.7 0.3 2.0 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EER29890.1 - 0.083 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF3237 PF11578.3 EER29891.1 - 4e-34 117.0 0.0 6.2e-34 116.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EER29891.1 - 2.2e-07 30.5 2.8 0.0066 16.1 0.2 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 EER29891.1 - 0.27 11.3 7.4 4.3 7.5 0.6 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Herpes_capsid PF06112.6 EER29891.1 - 0.33 11.0 11.3 11 6.0 7.5 2.8 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein Gln-synt_C PF00120.19 EER29892.1 - 2.2e-57 194.1 0.0 3e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 EER29893.1 - 4.8e-27 94.9 1.1 6.7e-27 94.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER29893.1 - 6.1e-17 62.1 0.0 7.5e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER29893.1 - 2.3e-09 37.1 0.5 3.8e-09 36.4 0.3 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EER29893.1 - 0.00014 21.6 0.1 0.00028 20.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EER29893.1 - 0.00025 20.5 0.0 0.00041 19.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EER29893.1 - 0.007 15.4 0.1 0.018 14.0 0.1 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EER29893.1 - 0.039 13.7 1.1 0.38 10.5 0.2 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EER29893.1 - 0.064 13.2 1.5 0.2 11.6 0.7 2.0 1 1 0 1 1 1 0 NADH(P)-binding Phos_pyr_kin PF08543.7 EER29893.1 - 0.077 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase MFS_1 PF07690.11 EER29894.1 - 1.5e-29 102.8 28.2 1.9e-29 102.4 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily LtrA PF06772.6 EER29894.1 - 0.0043 16.0 0.1 0.0043 16.0 0.0 1.7 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Synaptobrevin PF00957.16 EER29895.1 - 2.2e-33 113.7 0.5 2.5e-33 113.5 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF1035 PF06281.7 EER29895.1 - 0.05 13.3 3.2 0.083 12.6 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF619 PF04768.8 EER29896.1 - 4.4e-49 166.1 0.0 1e-48 164.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EER29896.1 - 3.7e-29 101.5 0.0 8.4e-29 100.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EER29896.1 - 3.3e-23 82.4 0.0 5.7e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EER29896.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_76 PF03663.9 EER29898.1 - 1.1e-156 521.8 7.7 1.4e-156 521.5 5.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EER29898.1 - 0.0013 17.8 7.9 0.012 14.6 3.1 2.9 1 1 0 2 2 2 1 Glycosyl Hydrolase Family 88 CBP4 PF07960.6 EER29899.1 - 3.3e-41 139.8 1.4 3.8e-41 139.6 1.0 1.0 1 0 0 1 1 1 1 CBP4 ERCC4 PF02732.10 EER29899.1 - 0.043 13.5 0.1 0.049 13.3 0.0 1.1 1 0 0 1 1 1 0 ERCC4 domain ATP12 PF07542.6 EER29899.1 - 0.053 13.4 0.4 0.062 13.2 0.3 1.2 1 0 0 1 1 1 0 ATP12 chaperone protein FinO_N PF12602.3 EER29899.1 - 1.4 9.2 9.0 2.3 8.5 6.2 1.5 1 1 0 1 1 1 0 Fertility inhibition protein N terminal Seryl_tRNA_N PF02403.17 EER29899.1 - 2.6 8.0 6.9 6.5 6.8 4.8 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sel1 PF08238.7 EER29900.1 - 2.6e-46 155.0 34.3 4.1e-08 33.5 0.2 8.0 8 0 0 8 8 8 7 Sel1 repeat TPR_20 PF14561.1 EER29900.1 - 0.048 13.7 2.3 0.067 13.3 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EER29900.1 - 0.063 13.5 1.3 22 5.5 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EER29900.1 - 0.26 11.8 9.3 2 9.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EER29900.1 - 1.1 10.0 15.5 2.8 8.7 1.7 5.2 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 EER29900.1 - 6 7.2 11.5 36 4.7 0.5 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat ABC_tran PF00005.22 EER29902.1 - 3.4e-47 160.2 0.0 1e-25 90.6 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EER29902.1 - 7.2e-16 58.9 0.2 0.0032 17.4 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EER29902.1 - 5.8e-12 45.3 0.1 0.00089 18.5 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EER29902.1 - 1.2e-07 32.5 0.1 0.016 16.0 0.0 3.6 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EER29902.1 - 3.8e-07 29.5 0.4 0.0083 15.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EER29902.1 - 6.8e-07 29.8 0.0 0.0052 17.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EER29902.1 - 1.3e-06 28.3 0.1 0.057 13.3 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EER29902.1 - 1.9e-06 27.5 1.1 0.15 11.5 0.1 4.4 5 1 0 5 5 4 2 AAA-like domain DUF258 PF03193.11 EER29902.1 - 4.8e-06 25.8 0.1 0.087 12.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EER29902.1 - 5.6e-06 25.6 0.0 0.16 11.0 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF87 PF01935.12 EER29902.1 - 1.1e-05 25.3 1.6 0.0083 15.9 0.1 3.4 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EER29902.1 - 1.7e-05 24.9 0.0 0.29 11.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EER29902.1 - 0.00024 20.9 0.0 0.8 9.6 0.0 3.4 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EER29902.1 - 0.00026 21.4 0.0 0.23 11.9 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EER29902.1 - 0.00032 21.0 0.0 0.47 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EER29902.1 - 0.0004 20.5 0.1 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Chromo PF00385.19 EER29902.1 - 0.00042 19.9 0.0 0.0009 18.8 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain NACHT PF05729.7 EER29902.1 - 0.00076 19.1 1.1 1.4 8.5 0.0 3.0 3 0 0 3 3 3 2 NACHT domain MobB PF03205.9 EER29902.1 - 0.00078 19.1 0.0 0.57 9.8 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EER29902.1 - 0.00087 18.1 0.2 0.31 9.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_28 PF13521.1 EER29902.1 - 0.0014 18.5 0.0 0.047 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF3584 PF12128.3 EER29902.1 - 0.0032 14.8 1.3 0.13 9.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_33 PF13671.1 EER29902.1 - 0.005 16.7 0.0 5.1 6.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EER29902.1 - 0.0056 16.5 0.0 1.7 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EER29902.1 - 0.012 15.0 0.0 6 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain Xpo1 PF08389.7 EER29902.1 - 0.022 14.7 0.7 0.072 12.9 0.0 2.2 2 1 0 2 2 2 0 Exportin 1-like protein PduV-EutP PF10662.4 EER29902.1 - 0.024 14.1 0.1 0.84 9.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EER29902.1 - 0.025 14.5 0.4 4.1 7.3 0.1 3.4 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.18 EER29902.1 - 0.03 14.1 0.0 1.1 8.9 0.0 3.3 3 0 0 3 3 3 0 Dynamin family DUF815 PF05673.8 EER29902.1 - 0.039 12.8 0.2 1 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP-synt_ab PF00006.20 EER29902.1 - 0.05 13.0 0.0 3.6 7.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EER29902.1 - 0.055 13.6 0.1 18 5.5 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EER29902.1 - 0.057 13.1 0.2 2.9 7.5 0.0 3.0 3 0 0 3 3 3 0 Archaeal ATPase AAA_13 PF13166.1 EER29902.1 - 0.068 11.6 2.0 3.2 6.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 EER29902.1 - 0.08 11.7 0.8 5.2 5.8 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.10 EER29902.1 - 0.12 12.1 1.0 7.2 6.2 0.0 3.0 3 0 0 3 3 2 0 NTPase HEAT PF02985.17 EER29902.1 - 0.13 12.3 1.5 1.2e+02 3.2 0.1 4.8 5 0 0 5 5 4 0 HEAT repeat Pox_A14 PF05767.7 EER29903.1 - 0.0056 16.5 1.4 0.013 15.4 0.3 2.1 2 0 0 2 2 2 1 Poxvirus virion envelope protein A14 Hom_end_hint PF05203.11 EER29904.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint Hint PF01079.15 EER29904.1 - 0.0014 17.8 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.1 EER29904.1 - 0.024 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Hint domain AA_permease_2 PF13520.1 EER29905.1 - 6.5e-46 156.7 51.1 8e-46 156.4 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EER29905.1 - 3.8e-22 78.2 40.0 5.2e-22 77.8 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_3 PF00933.16 EER29906.1 - 1.8e-87 293.1 0.0 2.5e-87 292.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EER29906.1 - 9.2e-52 175.8 0.0 3.6e-50 170.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EER29906.1 - 5.3e-21 74.3 0.8 1.8e-20 72.6 0.5 1.9 1 1 0 1 1 1 1 Fibronectin type III-like domain FMO-like PF00743.14 EER29907.1 - 8.7e-20 70.4 0.0 1.6e-17 62.8 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EER29907.1 - 1.1e-18 67.9 0.0 2.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EER29907.1 - 8.6e-10 38.5 0.0 2.8e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EER29907.1 - 1.4e-06 27.5 0.2 0.00018 20.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EER29907.1 - 0.0023 17.7 0.0 0.076 12.7 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EER29907.1 - 0.0078 15.1 0.0 0.18 10.6 0.0 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EER29907.1 - 0.0084 14.6 0.1 0.016 13.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EER29907.1 - 0.011 14.7 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EER29907.1 - 0.29 11.5 1.3 2 8.8 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FA_hydroxylase PF04116.8 EER29908.1 - 1.3e-16 61.0 25.7 2.9e-16 59.8 16.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M35 PF02102.10 EER29909.1 - 1.7e-106 355.9 1.5 2.1e-106 355.6 1.0 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EER29909.1 - 6.7e-07 29.9 0.8 1.2e-06 29.1 0.6 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EER29909.1 - 0.036 13.4 4.1 0.15 11.4 2.8 1.8 1 1 0 1 1 1 0 Putative peptidase family DUF2057 PF09829.4 EER29909.1 - 0.056 13.0 2.6 0.098 12.3 1.8 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Pkinase PF00069.20 EER29910.1 - 1e-28 100.2 0.0 1.2e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EER29910.1 - 8.7e-10 38.0 0.0 1.3e-09 37.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase MIP PF00230.15 EER29911.1 - 2.3e-49 167.9 7.4 2.8e-49 167.6 5.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein DUF4027 PF13219.1 EER29911.1 - 0.1 12.0 0.1 0.38 10.2 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) FGGY_C PF02782.11 EER29912.1 - 2.3e-72 242.7 0.9 3.6e-72 242.1 0.6 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EER29912.1 - 1.5e-70 237.2 0.0 2e-70 236.9 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Malate_synthase PF01274.17 EER29913.1 - 1.6e-234 778.7 0.0 1.9e-234 778.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase ADH_N PF08240.7 EER29915.1 - 1.8e-29 101.6 2.4 3.3e-29 100.8 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER29915.1 - 2.6e-22 78.7 0.0 4.5e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EER29915.1 - 0.0023 17.5 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 EER29915.1 - 0.0029 17.1 0.1 0.0079 15.7 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EER29915.1 - 0.0044 16.9 0.0 0.0075 16.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER29915.1 - 0.048 13.7 0.2 0.095 12.7 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MPC PF03650.8 EER29916.1 - 1.1e-41 141.5 0.2 1.5e-41 141.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 EER29917.1 - 2e-13 49.8 0.0 2.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain LigB PF02900.13 EER29918.1 - 7.6e-50 169.4 0.0 8.9e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.20 EER29919.1 - 3.3e-18 66.1 2.0 2.4e-17 63.3 1.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER29919.1 - 6.2e-07 29.2 0.7 1.9e-05 24.4 0.5 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EER29919.1 - 8.8e-07 28.9 0.0 2e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Citrate_synt PF00285.16 EER29920.1 - 4.9e-103 344.5 0.0 5.9e-103 344.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase adh_short PF00106.20 EER29921.1 - 7.8e-15 55.1 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EER29921.1 - 0.00011 21.8 0.0 0.0002 21.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EER29921.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EER29921.1 - 0.0021 17.8 0.0 0.0036 17.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EER29921.1 - 0.016 14.9 0.0 0.081 12.7 0.0 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ACPS PF01648.15 EER29921.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily ATP-synt_ab PF00006.20 EER29921.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Arylsulfotran_2 PF14269.1 EER29922.1 - 8.4e-121 402.7 0.1 1.3e-120 402.1 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EER29922.1 - 1.4e-12 46.9 0.0 3.3e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) B_lectin PF01453.19 EER29923.1 - 9.8e-12 44.7 0.0 2.5e-09 37.0 0.0 2.0 1 1 1 2 2 2 2 D-mannose binding lectin RTA1 PF04479.8 EER29924.1 - 2.3e-45 154.8 0.5 3.2e-45 154.3 0.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 EER29925.1 - 1.7e-08 34.2 11.8 2.6e-08 33.6 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EER29925.1 - 0.00084 18.0 0.2 0.0013 17.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Beta-lactamase PF00144.19 EER29926.1 - 3.5e-10 39.4 0.0 3.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EER29926.1 - 0.03 13.6 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase PTR2 PF00854.16 EER29927.1 - 3.5e-22 78.7 4.5 4.9e-22 78.2 3.1 1.1 1 0 0 1 1 1 1 POT family DUF3254 PF11630.3 EER29927.1 - 0.077 12.9 0.2 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) ATP-grasp_4 PF13535.1 EER29928.1 - 3.4e-21 75.8 0.0 4e-19 69.0 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EER29928.1 - 3.8e-08 32.9 0.0 3.4e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EER29928.1 - 9.6e-05 21.2 0.0 0.01 14.6 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EER29928.1 - 0.00071 18.9 0.0 0.0024 17.2 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EER29928.1 - 0.0019 18.0 0.0 0.0086 15.9 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_TupA PF14305.1 EER29928.1 - 0.052 12.8 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 TupA-like ATPgrasp LCCL PF03815.14 EER29929.1 - 1e-19 70.3 0.0 1.9e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 LCCL domain AMP-binding PF00501.23 EER29930.1 - 1.7e-64 217.7 0.0 2.1e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER29930.1 - 7.3e-09 36.4 0.1 1.8e-08 35.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1661 PF07877.6 EER29930.1 - 2.2 7.8 0.0 2.2 7.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1661) PBP PF01161.15 EER29931.1 - 1.6e-05 24.8 0.0 3.8e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MmgE_PrpD PF03972.9 EER29932.1 - 1.5e-150 501.2 0.0 1.8e-150 501.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family ICL PF00463.16 EER29933.1 - 1.6e-200 666.7 0.1 1.9e-200 666.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EER29933.1 - 3.8e-10 39.3 0.0 1.2e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase AAA_7 PF12775.2 EER29933.1 - 0.082 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region D3 DNA_methylase PF00145.12 EER29934.1 - 2.9e-28 98.9 0.0 4.3e-28 98.4 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Methyltransf_26 PF13659.1 EER29934.1 - 0.025 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GATase_2 PF00310.16 EER29935.1 - 1.9e-20 72.9 0.0 1.6e-16 59.9 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 EER29935.1 - 2.6e-14 53.0 0.0 6.6e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 EER29935.1 - 4.3e-14 52.5 0.0 9.7e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EER29935.1 - 2.5e-13 49.8 0.0 7.6e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EER29935.1 - 1.2e-06 27.4 0.0 2.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II HhH-GPD PF00730.20 EER29936.1 - 7.1e-10 39.1 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Aldedh PF00171.17 EER29937.1 - 1.3e-114 383.0 0.0 1.7e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Adeno_E3_CR2 PF02439.10 EER29938.1 - 0.036 13.5 1.4 0.036 13.5 0.9 2.0 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 ATP_synt_I PF03899.10 EER29938.1 - 0.053 13.6 0.5 0.057 13.5 0.3 1.1 1 0 0 1 1 1 0 ATP synthase I chain Cation_efflux PF01545.16 EER29938.1 - 0.079 12.0 1.9 0.089 11.8 1.4 1.1 1 0 0 1 1 1 0 Cation efflux family Glycoprotein_B PF00606.13 EER29938.1 - 0.12 10.3 0.6 0.12 10.3 0.4 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B SCAN PF02023.12 EER29939.1 - 0.035 13.5 0.8 0.33 10.4 0.2 2.4 2 0 0 2 2 2 0 SCAN domain Mt_ATP-synt_D PF05873.7 EER29941.1 - 1.3e-18 67.1 1.3 1.5e-18 66.9 0.9 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) AAA_27 PF13514.1 EER29941.1 - 0.019 12.7 4.6 0.023 12.3 3.2 1.0 1 0 0 1 1 1 0 AAA domain ABC_tran_2 PF12848.2 EER29941.1 - 0.057 13.2 1.1 0.12 12.2 0.8 1.5 1 0 0 1 1 1 0 ABC transporter Syntaxin PF00804.20 EER29941.1 - 0.17 12.0 2.8 0.31 11.2 2.0 1.5 1 1 0 1 1 1 0 Syntaxin BLOC1_2 PF10046.4 EER29941.1 - 0.19 11.8 3.9 0.29 11.2 1.5 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.15 EER29941.1 - 0.35 9.9 7.8 0.14 11.2 0.3 2.1 1 1 1 2 2 2 0 Tropomyosin Atg14 PF10186.4 EER29941.1 - 0.56 9.1 2.8 0.68 8.8 1.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF848 PF05852.6 EER29941.1 - 0.66 9.8 4.4 2.5 7.9 3.0 1.9 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Spectrin PF00435.16 EER29941.1 - 1.6 9.0 4.9 2.7 8.3 0.7 2.5 1 1 2 3 3 3 0 Spectrin repeat NAC PF01849.13 EER29942.1 - 1.5e-24 85.2 0.0 8.6e-23 79.6 0.0 2.3 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EER29942.1 - 4.5e-05 23.1 0.4 0.0001 22.0 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain SpoIIIAH PF12685.2 EER29942.1 - 0.13 11.7 7.9 0.067 12.6 3.2 1.8 2 0 0 2 2 2 0 SpoIIIAH-like protein Ribosomal_L14e PF01929.12 EER29943.1 - 7.1e-29 99.9 1.0 1.1e-28 99.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EER29943.1 - 3e-08 33.0 0.4 5.4e-08 32.2 0.3 1.4 1 0 0 1 1 1 1 KOW motif DRY_EERY PF09750.4 EER29943.1 - 0.27 11.3 2.1 0.8 9.8 1.4 1.8 1 1 0 1 1 1 0 Alternative splicing regulator DUF4398 PF14346.1 EER29943.1 - 1.6 8.8 10.2 0.63 10.1 1.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) RGS PF00615.14 EER29944.1 - 6.3e-07 29.5 0.1 3.1e-05 24.0 0.1 2.2 1 1 0 1 1 1 1 Regulator of G protein signaling domain RNA_binding PF01877.12 EER29944.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA binding MFS_1 PF07690.11 EER29945.1 - 1.9e-40 138.6 33.3 2.3e-33 115.4 6.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EER29945.1 - 4e-15 55.3 7.5 1.6e-12 46.8 2.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EER29945.1 - 1e-09 37.3 9.6 4e-06 25.4 2.2 3.5 1 1 1 2 2 2 2 MFS/sugar transport protein Folate_carrier PF01770.13 EER29945.1 - 4.7e-05 22.0 0.1 8.7e-05 21.2 0.1 1.3 1 0 0 1 1 1 1 Reduced folate carrier MFS_1_like PF12832.2 EER29945.1 - 0.012 15.4 0.3 0.52 10.1 0.0 2.9 2 0 0 2 2 2 0 MFS_1 like family TRI12 PF06609.8 EER29945.1 - 0.022 12.9 1.3 0.042 12.0 0.9 1.4 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) LAP1C PF05609.7 EER29945.1 - 0.097 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SRP-alpha_N PF04086.8 EER29946.1 - 6e-75 252.2 0.0 8.5e-75 251.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EER29946.1 - 1e-49 168.6 0.0 1.9e-49 167.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EER29946.1 - 1.3e-06 28.4 0.0 3.9e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EER29946.1 - 8.1e-06 24.7 0.0 1.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EER29946.1 - 9.2e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EER29946.1 - 0.0015 18.5 0.0 0.0043 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 EER29946.1 - 0.0024 17.4 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EER29946.1 - 0.0053 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 EER29946.1 - 0.027 13.6 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EER29946.1 - 0.027 13.8 0.0 0.06 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EER29946.1 - 0.046 14.0 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.18 EER29946.1 - 0.055 13.4 0.0 0.17 11.8 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EER29946.1 - 0.056 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EER29946.1 - 0.12 12.3 0.4 0.59 10.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain YIF1 PF03878.10 EER29947.1 - 2.8e-74 249.2 1.3 3.5e-74 248.9 0.9 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EER29947.1 - 0.16 11.4 10.8 0.09 12.2 6.0 1.6 2 0 0 2 2 2 0 Yip1 domain RNase_T PF00929.19 EER29948.1 - 3.5e-17 63.1 0.0 8.2e-17 61.9 0.0 1.7 1 0 0 1 1 1 1 Exonuclease Catalase PF00199.14 EER29949.1 - 7.5e-163 541.6 0.4 9.6e-163 541.3 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EER29949.1 - 9.1e-19 67.0 0.1 1.9e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EER29949.1 - 0.00022 20.7 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family HpcH_HpaI PF03328.9 EER29951.1 - 6e-27 93.9 0.0 8.1e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family p450 PF00067.17 EER29952.1 - 0.05 12.1 0.1 0.068 11.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 NAD_binding_4 PF07993.7 EER29953.1 - 2.9e-34 118.1 0.0 4.4e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EER29953.1 - 1.4e-25 89.5 0.0 2.5e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 EER29953.1 - 6.4e-08 32.7 0.0 1.5e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EER29953.1 - 1e-07 31.6 0.0 1.7e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EER29953.1 - 0.036 13.9 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase MFS_1 PF07690.11 EER29954.1 - 1.9e-38 132.0 47.5 1.9e-38 132.0 32.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EER29954.1 - 1e-11 43.8 14.1 1.4e-11 43.3 9.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DIT1_PvcA PF05141.7 EER29955.1 - 1.8e-89 299.7 0.0 2.1e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein RabGAP-TBC PF00566.13 EER29956.1 - 1.5e-38 132.4 1.5 2.6e-38 131.6 1.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EER29956.1 - 7e-11 41.8 0.0 1.9e-07 30.5 0.0 3.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3548) GAS2 PF02187.12 EER29957.1 - 3.5e-05 23.4 0.1 7.5e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hus1 PF04005.7 EER29958.1 - 6.8e-111 369.8 0.0 7.6e-111 369.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 EER29959.1 - 4.4e-106 354.7 0.1 6.3e-106 354.2 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 EER29959.1 - 1.1e-39 136.9 15.1 1.1e-39 136.9 10.4 2.7 1 1 1 2 2 2 2 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 EER29959.1 - 1.4e-32 112.0 0.0 3.4e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 EER29960.1 - 3e-17 62.4 0.0 6.5e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EER29960.1 - 3.2e-15 57.1 0.0 4.1e-14 53.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EER29960.1 - 1.6e-09 38.2 0.0 4.5e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EER29960.1 - 5.4e-07 29.4 0.0 2.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EER29960.1 - 0.00078 19.0 0.0 0.014 15.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Mso1_Sec1_bdg PF14475.1 EER29961.1 - 1.2e-08 34.1 0.0 2.1e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 EER29962.1 - 1.1e-32 112.8 0.6 2e-32 112.0 0.4 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EER29962.1 - 3.3e-22 78.4 18.9 3.3e-22 78.4 13.1 2.7 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EER29962.1 - 0.006 15.7 25.2 0.011 14.8 17.6 1.2 1 1 0 1 1 1 1 BUD22 Nop14 PF04147.7 EER29962.1 - 0.038 11.9 27.3 0.052 11.4 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family UCR_14kD PF02271.11 EER29962.1 - 0.072 12.8 1.4 0.19 11.5 1.0 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit CDC45 PF02724.9 EER29962.1 - 5.4 4.9 17.7 3.2 5.6 9.9 1.9 2 0 0 2 2 2 0 CDC45-like protein Amidase PF01425.16 EER29963.1 - 7.7e-92 308.4 0.0 1e-91 308.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Ldh_2 PF02615.9 EER29964.1 - 7.6e-97 324.0 0.0 8.6e-97 323.8 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase DUF3402 PF11882.3 EER29965.1 - 1.1e-159 531.8 0.0 1.5e-159 531.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EER29965.1 - 9.3e-85 284.0 0.0 1.3e-84 283.4 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein GST_N_2 PF13409.1 EER29965.1 - 0.0056 16.6 0.2 0.028 14.4 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Neurensin PF14927.1 EER29966.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 Neurensin PAP2 PF01569.16 EER29967.1 - 4.7e-16 58.6 5.5 1.5e-15 56.9 3.7 1.8 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 EER29967.1 - 0.0002 21.0 0.0 0.018 14.7 0.0 2.3 2 0 0 2 2 2 2 Divergent PAP2 family 7TMR-DISM_7TM PF07695.6 EER29967.1 - 0.11 12.1 7.1 0.058 13.0 1.7 2.0 2 0 0 2 2 2 0 7TM diverse intracellular signalling UbiA PF01040.13 EER29967.1 - 0.18 10.9 7.8 0.12 11.5 2.5 2.1 1 1 1 2 2 2 0 UbiA prenyltransferase family RWD PF05773.17 EER29968.1 - 1.7e-19 69.7 0.0 3.3e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EER29968.1 - 4.7e-17 61.6 36.3 1.2e-12 47.4 0.4 4.2 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EER29968.1 - 6.7e-05 22.6 10.4 6.7e-05 22.6 7.2 3.6 3 0 0 3 3 3 2 Ring finger domain DUF2868 PF11067.3 EER29968.1 - 6.3 5.8 5.7 10 5.1 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) CRT10 PF08728.5 EER29969.1 - 9e-21 73.5 0.0 5.1e-13 47.9 0.0 2.2 2 0 0 2 2 2 2 CRT10 MMtag PF10159.4 EER29970.1 - 1e-32 112.0 4.0 1e-32 112.0 2.8 3.0 3 1 1 4 4 4 1 Kinase phosphorylation protein Glyco_hydro_63 PF03200.11 EER29971.1 - 1.1e-249 830.5 0.0 9.3e-249 827.4 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EER29971.1 - 0.00014 20.6 0.2 0.014 14.0 0.0 2.3 2 0 0 2 2 2 2 Trehalase DAO PF01266.19 EER29972.1 - 1.2e-61 208.6 0.1 1.4e-61 208.4 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EER29972.1 - 3.3e-05 23.8 0.2 7.2e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EER29972.1 - 0.011 14.5 0.5 0.1 11.3 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_2 PF07992.9 EER29972.1 - 0.06 13.2 1.1 6.4 6.5 0.6 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EER29972.1 - 0.086 13.2 0.7 0.51 10.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.10 EER29972.1 - 0.11 10.6 0.0 1.6 6.8 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.9 EER29972.1 - 0.13 10.8 1.4 0.81 8.2 0.3 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 EER29972.1 - 0.14 11.2 0.5 0.32 10.0 0.4 1.6 1 0 0 1 1 1 0 Thi4 family Exo_endo_phos PF03372.18 EER29973.1 - 1.5e-10 41.4 0.0 1.9e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M36 PF02128.10 EER29974.1 - 7e-165 548.4 5.3 9.2e-165 548.0 3.7 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EER29974.1 - 3.4e-13 48.8 7.0 7.2e-13 47.7 4.1 2.1 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EER29974.1 - 0.0036 17.0 0.0 0.0079 15.9 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_S8 PF00082.17 EER29975.1 - 2.9e-34 118.4 10.0 1e-29 103.5 2.2 2.8 2 1 1 3 3 3 2 Subtilase family Inhibitor_I9 PF05922.11 EER29975.1 - 1.1e-12 48.3 0.0 2.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1777 PF08648.7 EER29976.1 - 6.4e-28 97.7 40.8 6.4e-28 97.7 28.3 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Elong_Iki1 PF10483.4 EER29977.1 - 2.8e-89 299.1 0.0 3.3e-89 298.9 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.1 EER29978.1 - 1.9e-29 101.0 0.3 3.4e-29 100.2 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EER29978.1 - 3.8e-15 55.2 0.0 6.9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin ASXH PF13919.1 EER29979.1 - 5.9e-44 149.2 0.7 1.1e-43 148.2 0.5 1.4 1 0 0 1 1 1 1 Asx homology domain adh_short PF00106.20 EER29980.1 - 6.3e-11 42.4 0.0 1.5e-10 41.2 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EER29980.1 - 3.5e-09 36.7 0.0 1.5e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EER29980.1 - 0.00048 19.8 0.0 0.0021 17.7 0.0 1.9 2 0 0 2 2 2 1 KR domain MULE PF10551.4 EER29980.1 - 0.018 15.2 0.0 0.065 13.4 0.0 1.9 2 0 0 2 2 2 0 MULE transposase domain CLPTM1 PF05602.7 EER29981.1 - 1.6e-162 541.2 0.0 2e-162 540.8 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1240 PF06836.7 EER29981.1 - 0.32 11.2 2.9 0.76 10.0 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) DUF4360 PF14273.1 EER29982.1 - 5.6e-64 215.1 1.1 6.6e-64 214.9 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) CENP-I PF07778.6 EER29983.1 - 8.4e-92 307.9 0.3 1.3e-91 307.3 0.2 1.1 1 0 0 1 1 1 1 Mis6 Transcrip_reg PF01709.15 EER29984.1 - 3.6e-62 209.5 0.5 4e-62 209.3 0.3 1.0 1 0 0 1 1 1 1 Transcriptional regulator HEAT PF02985.17 EER29985.1 - 1.9e-13 49.2 21.6 0.0054 16.7 0.0 10.4 12 0 0 12 12 12 5 HEAT repeat HEAT_2 PF13646.1 EER29985.1 - 7.7e-12 45.3 9.3 0.084 13.1 0.0 8.4 8 1 1 9 9 9 3 HEAT repeats Vac14_Fab1_bd PF12755.2 EER29985.1 - 5.6e-09 36.2 0.2 0.08 13.3 0.0 5.7 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EER29985.1 - 2e-06 28.0 11.6 0.36 11.3 0.0 8.7 9 0 0 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 EER29985.1 - 0.0058 16.0 6.3 0.68 9.2 0.0 4.5 5 0 0 5 5 5 1 CLASP N terminal DUF1640 PF07798.6 EER29986.1 - 4.9e-15 56.0 2.8 7.3e-15 55.4 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) ALMT PF11744.3 EER29986.1 - 0.046 12.3 2.2 0.064 11.8 1.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Vps51 PF08700.6 EER29987.1 - 3.8e-13 49.0 0.1 1.6e-12 47.0 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 DUF4208 PF13907.1 EER29987.1 - 0.033 14.4 0.1 2 8.6 0.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) D123 PF07065.9 EER29988.1 - 7.4e-79 264.9 0.0 1.2e-78 264.2 0.0 1.3 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EER29988.1 - 0.088 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) ECH PF00378.15 EER29989.1 - 1.8e-26 92.8 0.0 2e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2346 PF09803.4 EER29990.1 - 0.0049 16.6 3.0 0.0098 15.7 2.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) DUF3966 PF13110.1 EER29990.1 - 0.19 11.5 1.4 0.3 10.9 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) DUF3317 PF11779.3 EER29991.1 - 1.9e-21 75.2 4.6 2.6e-21 74.7 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) GMC_oxred_N PF00732.14 EER29992.1 - 6e-68 229.1 0.0 1.2e-67 228.1 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EER29992.1 - 1.9e-30 106.0 0.1 3e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EER29992.1 - 1.4e-05 24.1 0.2 0.00027 19.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EER29992.1 - 2.1e-05 23.5 0.1 0.0002 20.3 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EER29992.1 - 3.5e-05 22.8 0.1 5.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EER29992.1 - 5.3e-05 23.1 0.2 0.00013 21.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EER29992.1 - 0.0017 18.3 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EER29992.1 - 0.0026 17.8 0.1 2.2 8.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EER29992.1 - 0.0065 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EER29992.1 - 0.0083 14.6 0.0 0.016 13.7 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EER29992.1 - 0.042 14.2 0.1 0.25 11.7 0.0 2.4 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EER29992.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EER29992.1 - 0.12 12.3 0.0 0.33 10.9 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain RF-1 PF00472.15 EER29993.1 - 3.7e-25 87.9 5.1 4.6e-25 87.6 3.4 1.2 1 1 0 1 1 1 1 RF-1 domain MIR PF02815.14 EER29993.1 - 0.076 12.5 0.3 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 MIR domain U79_P34 PF03064.11 EER29993.1 - 0.21 11.0 6.7 0.23 10.9 4.6 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PBP_sp32 PF07222.7 EER29993.1 - 2 7.5 5.7 2.3 7.3 3.9 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Peptidase_S49_N PF08496.5 EER29993.1 - 6 6.6 8.4 7.5 6.3 5.8 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CAS_CSE1 PF03378.10 EER29994.1 - 2e-181 603.0 0.0 3.4e-181 602.2 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EER29994.1 - 2.8e-154 513.1 0.8 4.1e-154 512.6 0.5 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 EER29994.1 - 3.8e-13 49.1 0.2 1.8e-12 47.0 0.1 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EER29994.1 - 0.013 15.3 0.9 0.22 11.4 0.0 3.5 4 1 0 4 4 4 0 Exportin 1-like protein DUF3384 PF11864.3 EER29995.1 - 1.1e-76 258.1 0.0 2e-76 257.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EER29995.1 - 1.9e-48 164.3 0.0 3.2e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EER29995.1 - 2e-29 102.7 0.4 2.4e-27 95.9 0.0 3.0 3 0 0 3 3 3 1 Tuberin PUF PF00806.14 EER29996.1 - 8.8e-58 188.6 13.6 1.6e-07 30.3 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Phosphodiest PF01663.17 EER29997.1 - 3.6e-15 56.1 0.7 7.2e-15 55.1 0.5 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EER29997.1 - 5.1e-07 29.3 1.3 9.1e-07 28.5 0.9 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EER29997.1 - 2.6e-05 23.5 0.1 4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Sulfatase cwf21 PF08312.7 EER29998.1 - 1.1e-13 50.7 25.3 1.1e-13 50.7 17.6 2.3 2 1 0 2 2 2 1 cwf21 domain DUF3650 PF12368.3 EER29998.1 - 0.017 14.6 0.3 0.017 14.6 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3650) Fmp27_WPPW PF10359.4 EER29998.1 - 0.032 12.6 2.9 0.036 12.4 2.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GvpL_GvpF PF06386.6 EER29998.1 - 0.29 10.7 6.4 0.37 10.3 4.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF972 PF06156.8 EER29998.1 - 0.59 10.4 4.3 1.1 9.6 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EER29998.1 - 1.4 8.7 14.4 4 7.3 1.2 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Paf1 PF03985.8 EER29998.1 - 2.6 6.6 11.4 3.9 6.1 7.9 1.2 1 0 0 1 1 1 0 Paf1 Helicase_C PF00271.26 EER29999.1 - 3.1e-15 55.8 0.0 2.2e-14 53.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EER29999.1 - 8.1e-12 44.9 0.0 2.5e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EER29999.1 - 5.6e-11 42.3 0.0 1.6e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.24 EER29999.1 - 2e-09 37.1 0.1 1.2e-07 31.3 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EER29999.1 - 7.9e-05 22.5 0.7 0.5 10.1 0.0 3.2 4 0 0 4 4 4 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EER29999.1 - 0.00032 20.8 0.0 0.0017 18.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EER29999.1 - 0.0079 15.1 0.0 0.017 14.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EER29999.1 - 3.5 7.8 12.4 1.1 9.5 0.4 2.9 2 1 0 2 2 2 0 AAA domain DUF2372 PF10178.4 EER30000.1 - 0.021 14.9 0.0 0.054 13.6 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) Cohesin_load PF10345.4 EER30001.1 - 1.5e-160 535.3 13.3 1.9e-160 535.0 9.2 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.1 EER30001.1 - 0.00055 19.8 13.1 0.0095 15.8 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Lactamase_B_4 PF13691.1 EER30001.1 - 0.028 13.8 0.0 0.09 12.2 0.0 1.8 2 0 0 2 2 2 0 tRNase Z endonuclease LdpA_C PF12617.3 EER30001.1 - 0.037 13.2 0.5 0.091 12.0 0.1 1.8 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal Histone PF00125.19 EER30002.1 - 8.1e-28 96.3 0.1 1.2e-27 95.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EER30002.1 - 0.00022 21.3 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EER30002.1 - 0.0015 17.8 3.7 0.0066 15.7 2.5 1.8 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EER30002.1 - 0.092 12.8 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FXR1P_C PF12235.3 EER30002.1 - 1.1 9.3 18.2 1.7 8.7 12.6 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal EMP70 PF02990.11 EER30003.1 - 3.4e-148 494.3 7.3 7.3e-147 489.9 5.1 2.6 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3169 PF11368.3 EER30003.1 - 1.3 8.1 5.2 0.87 8.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) ubiquitin PF00240.18 EER30004.1 - 9.3e-19 66.5 0.0 1.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EER30004.1 - 1.4e-09 37.4 0.1 3.8e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EER30004.1 - 5.8e-07 29.0 0.0 9.4e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EER30004.1 - 0.002 18.2 0.0 0.0046 17.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EER30004.1 - 0.0037 17.1 0.0 0.0069 16.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EER30004.1 - 0.048 13.9 0.1 0.15 12.2 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain CPSF_A PF03178.10 EER30005.1 - 1.5e-103 346.2 0.0 3.7e-102 341.7 0.0 2.8 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EER30005.1 - 3.4e-67 226.7 0.0 5.4e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 EER30005.1 - 0.0002 21.0 0.0 0.27 10.8 0.0 3.3 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal Lactonase PF10282.4 EER30005.1 - 0.15 11.1 0.0 6.2 5.7 0.0 3.1 3 1 1 4 4 4 0 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EER30005.1 - 0.37 10.7 1.4 0.74 9.7 0.1 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat ALO PF04030.9 EER30008.1 - 5.1e-07 29.5 3.3 2.1e-06 27.5 2.3 1.8 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EER30008.1 - 3.7e-05 23.2 0.0 0.0055 16.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pkinase PF00069.20 EER30009.1 - 0.0034 16.5 0.2 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain CN_hydrolase PF00795.17 EER30010.1 - 9.9e-24 83.7 0.0 1.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase BP28CT PF08146.7 EER30011.1 - 1e-46 158.4 0.9 4.8e-46 156.2 0.1 2.7 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EER30011.1 - 4.5e-28 97.6 6.7 8.5e-28 96.7 0.3 4.7 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EER30011.1 - 1.6e-08 34.6 15.1 0.052 13.8 0.1 7.1 6 3 2 8 8 8 5 HEAT repeats HEAT_EZ PF13513.1 EER30011.1 - 7.8e-05 23.0 17.9 0.47 11.0 0.1 8.0 7 2 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 EER30011.1 - 0.00016 21.4 7.7 0.044 13.8 0.1 6.7 6 0 0 6 6 6 1 HEAT repeat Arm PF00514.18 EER30011.1 - 0.066 13.0 5.6 0.95 9.3 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat NRDE-2 PF08424.5 EER30012.1 - 1.9e-87 293.2 0.0 8.2e-86 287.8 0.0 2.7 3 0 0 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EER30012.1 - 0.94 10.3 6.1 1.5e+02 3.4 0.0 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat UDG PF03167.14 EER30013.1 - 2.3e-19 69.3 0.0 3.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily 7TMR-DISM_7TM PF07695.6 EER30014.1 - 0.25 10.9 5.7 0.46 10.1 4.0 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling NAD_binding_6 PF08030.7 EER30015.1 - 6e-24 84.7 0.0 1e-23 83.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EER30015.1 - 1.4e-23 82.7 0.0 2.7e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EER30015.1 - 6.6e-08 32.6 7.8 1.4e-06 28.4 5.4 2.3 1 1 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EER30015.1 - 0.00051 20.1 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EER30015.1 - 0.013 16.0 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain SBDS PF01172.13 EER30016.1 - 4.5e-27 93.6 0.7 5.3e-27 93.4 0.5 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EER30016.1 - 0.00074 19.2 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Phage XkdN-like protein VOMI PF03762.12 EER30016.1 - 0.041 13.8 0.0 0.049 13.5 0.0 1.2 1 1 0 1 1 1 0 Vitelline membrane outer layer protein I (VOMI) RhoGEF PF00621.15 EER30017.1 - 3.1e-06 27.1 0.0 1.2e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 RhoGEF domain PH PF00169.24 EER30017.1 - 0.0013 18.9 1.0 0.011 15.9 0.0 2.7 3 0 0 3 3 3 1 PH domain Rep_fac_C PF08542.6 EER30017.1 - 0.049 13.6 0.1 5.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Replication factor C C-terminal domain PDZ_2 PF13180.1 EER30018.1 - 1.2e-05 25.0 0.0 3.1e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 EER30018.1 - 3.2e-05 23.9 0.0 6.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 EER30018.1 - 3.8e-05 23.7 0.3 7.4e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 EER30019.1 - 4.3e-49 166.0 0.0 5.2e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EER30019.1 - 3.2e-15 56.6 0.0 6.9e-15 55.5 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EER30019.1 - 6.1e-10 38.6 0.0 8.4e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EER30019.1 - 0.0011 19.1 0.1 0.0084 16.2 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EER30019.1 - 0.003 16.7 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EER30019.1 - 0.02 13.6 1.1 0.97 8.0 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 EER30019.1 - 0.033 13.5 0.1 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DUF815 PF05673.8 EER30019.1 - 0.065 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EER30019.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EER30019.1 - 0.082 13.0 0.1 0.21 11.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain STAS PF01740.16 EER30019.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 STAS domain UPF0079 PF02367.12 EER30019.1 - 0.15 11.7 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SNF2_N PF00176.18 EER30020.1 - 8.4e-74 248.0 0.9 1.4e-73 247.3 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EER30020.1 - 2.4e-12 46.5 0.0 1.2e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EER30020.1 - 2.2e-09 36.8 3.3 4.5e-09 35.8 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EER30020.1 - 1.4e-07 31.3 5.4 3.2e-07 30.2 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EER30020.1 - 3.6e-07 29.9 3.6 7.2e-07 28.9 2.5 1.6 1 0 0 1 1 1 1 Ring finger domain DEAD PF00270.24 EER30020.1 - 6.3e-06 25.7 0.0 1.8e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EER30020.1 - 1.8e-05 24.3 4.2 4.6e-05 23.0 2.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EER30020.1 - 3.6e-05 23.3 4.4 8.7e-05 22.1 3.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EER30020.1 - 4.8e-05 22.8 5.1 0.00026 20.5 3.5 2.2 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EER30020.1 - 0.0002 21.0 1.4 0.00059 19.5 1.0 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EER30020.1 - 0.00071 19.3 5.9 0.0016 18.2 4.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Fungal_trans PF04082.13 EER30021.1 - 3.4e-20 72.0 0.6 7.3e-20 70.9 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER30021.1 - 1.1e-10 41.1 10.7 1.1e-10 41.1 7.4 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EER30022.1 - 4.2e-34 115.1 16.5 4.5e-09 35.8 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EER30022.1 - 1.4e-08 33.4 0.0 1.3e-05 23.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EER30022.1 - 4.2e-05 23.3 0.0 0.18 11.5 0.0 2.7 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EER30022.1 - 0.011 15.1 0.0 0.6 9.6 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 EER30022.1 - 0.017 13.2 0.4 0.18 9.9 0.3 2.1 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EER30022.1 - 0.08 11.7 0.0 0.16 10.7 0.0 1.6 1 1 1 2 2 2 0 Coatomer WD associated region Ribonuc_P_40 PF08584.6 EER30023.1 - 9.4e-70 234.8 0.0 1.1e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Dna2 PF08696.6 EER30024.1 - 5.8e-71 238.0 0.0 1.1e-70 237.2 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EER30024.1 - 3.5e-51 173.4 0.0 5.8e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EER30024.1 - 1.2e-40 139.5 0.2 2.9e-21 76.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EER30024.1 - 4e-14 52.6 0.0 8.9e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EER30024.1 - 5.2e-11 42.1 0.2 1.5e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 EER30024.1 - 1.1e-10 41.7 0.0 2.9e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 EER30024.1 - 5.1e-10 39.1 1.3 9.3e-10 38.3 0.2 1.9 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 EER30024.1 - 5.2e-07 29.4 0.5 0.13 11.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF911 PF06023.7 EER30024.1 - 0.00011 21.5 0.0 0.00025 20.3 0.0 1.5 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) SRP54 PF00448.17 EER30024.1 - 0.00019 20.9 0.1 0.00039 19.9 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.16 EER30024.1 - 0.00021 20.6 0.0 0.00056 19.3 0.0 1.7 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain CbiA PF01656.18 EER30024.1 - 0.0003 20.2 0.1 0.0016 17.9 0.0 2.2 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Helicase_RecD PF05127.9 EER30024.1 - 0.00052 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.1 EER30024.1 - 0.0032 17.4 0.9 0.0066 16.4 0.0 2.0 2 0 0 2 2 1 1 AAA ATPase domain AAA_25 PF13481.1 EER30024.1 - 0.0035 16.7 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EER30024.1 - 0.0038 16.9 0.1 0.0094 15.6 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EER30024.1 - 0.016 14.2 0.2 0.066 12.1 0.1 1.9 1 1 0 1 1 1 0 PIF1-like helicase MMR_HSR1 PF01926.18 EER30024.1 - 0.022 14.7 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase ArgK PF03308.11 EER30024.1 - 0.042 12.6 0.0 0.077 11.7 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DUF87 PF01935.12 EER30024.1 - 0.042 13.6 2.0 0.27 11.0 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_5 PF07728.9 EER30024.1 - 0.048 13.3 0.1 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 EER30024.1 - 0.051 12.2 0.1 0.087 11.4 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EER30024.1 - 0.081 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 EER30024.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mito_carr PF00153.22 EER30025.1 - 3.1e-57 190.2 2.7 1.4e-20 72.7 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein HLH PF00010.21 EER30026.1 - 7.2e-12 44.8 0.0 1.9e-11 43.4 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Got1 PF04178.7 EER30027.1 - 7.7e-32 109.8 18.8 1e-31 109.5 13.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family tRNA_lig_CPD PF08302.6 EER30028.1 - 1.2e-80 270.4 0.0 1.6e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EER30028.1 - 1.1e-78 263.7 0.0 1.6e-78 263.2 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EER30028.1 - 2.4e-52 177.2 0.6 3.9e-52 176.4 0.4 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_33 PF13671.1 EER30028.1 - 0.00079 19.3 0.1 0.0022 17.8 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EER30028.1 - 0.071 13.9 0.2 0.48 11.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain Ank_5 PF13857.1 EER30029.1 - 1.5e-13 50.5 0.1 1.8e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EER30029.1 - 5.3e-09 36.3 0.0 1.9e-08 34.6 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EER30029.1 - 1.6e-06 27.6 0.1 1.9e-05 24.1 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EER30029.1 - 9.9e-06 25.8 0.1 6.9e-05 23.1 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EER30029.1 - 0.00016 21.5 0.1 0.00064 19.7 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat YejG PF13989.1 EER30029.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 YejG-like protein DUF3107 PF11305.3 EER30029.1 - 0.094 12.6 0.2 7.4 6.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3107) Mod_r PF07200.8 EER30030.1 - 5e-12 45.9 2.9 7.3e-12 45.4 2.0 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein PAT1 PF09770.4 EER30030.1 - 6.9 4.7 7.8 7.9 4.5 5.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAP2 PF01569.16 EER30031.1 - 3.4e-22 78.4 2.6 3.4e-22 78.4 1.8 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EER30031.1 - 0.011 15.2 1.4 0.17 11.3 0.0 2.3 2 0 0 2 2 2 0 PAP2 superfamily DIE2_ALG10 PF04922.7 EER30031.1 - 0.017 14.1 0.1 0.29 10.1 0.0 2.0 2 0 0 2 2 2 0 DIE2/ALG10 family Aldo_ket_red PF00248.16 EER30032.1 - 2.2e-58 197.3 0.1 2.6e-58 197.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NPR3 PF03666.8 EER30034.1 - 1.8e-151 504.7 0.0 7.7e-151 502.6 0.0 1.9 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EER30034.1 - 0.0078 14.9 0.1 0.014 14.1 0.1 1.3 1 0 0 1 1 1 1 Nitrogen permease regulator 2 La PF05383.12 EER30035.1 - 7.3e-18 64.1 0.3 1.3e-17 63.3 0.2 1.4 1 0 0 1 1 1 1 La domain Band_7 PF01145.20 EER30036.1 - 4.1e-32 111.5 0.5 7.8e-32 110.6 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EER30036.1 - 0.036 13.5 0.0 0.067 12.6 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family Hira PF07569.6 EER30037.1 - 8.4e-82 273.6 0.0 4.6e-81 271.2 0.0 2.2 3 0 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.27 EER30037.1 - 8.3e-40 133.2 21.6 1.2e-07 31.3 0.0 8.7 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EER30037.1 - 1.1e-10 40.7 0.1 4.1e-10 38.9 0.1 2.1 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EER30037.1 - 6.2e-06 25.7 2.2 6.2 6.5 0.0 5.5 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EER30037.1 - 0.014 15.0 0.6 1 9.0 0.2 3.6 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EER30037.1 - 0.032 12.0 0.1 0.075 10.8 0.0 1.5 2 0 0 2 2 2 0 IKI3 family YchF-GTPase_C PF06071.8 EER30038.1 - 6.4e-33 112.3 0.3 1.5e-32 111.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EER30038.1 - 2.2e-12 46.9 0.0 8e-12 45.1 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EER30038.1 - 0.00079 18.7 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EER30038.1 - 0.013 15.3 0.1 0.061 13.1 0.1 2.2 2 1 0 2 2 2 0 TGS domain AAA_18 PF13238.1 EER30038.1 - 0.055 13.7 0.3 33 4.8 0.5 3.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EER30038.1 - 0.066 13.1 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EER30038.1 - 0.093 12.4 0.3 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SecA_PP_bind PF01043.15 EER30038.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 SecA preprotein cross-linking domain AAA_23 PF13476.1 EER30038.1 - 0.55 10.5 3.5 3.1 8.0 2.4 2.1 1 1 0 1 1 1 0 AAA domain PUA PF01472.15 EER30039.1 - 7.9e-14 51.1 0.0 1.4e-13 50.3 0.0 1.4 1 1 0 1 1 1 1 PUA domain RIC1 PF07064.8 EER30040.1 - 1.9e-87 292.9 0.0 2.7e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 RIC1 TPR_11 PF13414.1 EER30041.1 - 1.2e-19 69.7 5.5 1.5e-15 56.5 0.6 2.4 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EER30041.1 - 3.6e-13 48.3 6.1 0.00064 19.4 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EER30041.1 - 9.7e-13 47.1 3.2 0.00067 19.1 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EER30041.1 - 1.4e-08 34.3 0.5 0.0021 18.1 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EER30041.1 - 1.5e-08 35.1 16.0 1.1e-05 26.0 1.2 2.9 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EER30041.1 - 2.8e-06 27.4 5.2 0.019 15.5 0.4 3.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EER30041.1 - 5.2e-06 26.3 2.5 0.0066 16.3 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EER30041.1 - 6.5e-06 25.5 0.2 0.41 10.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EER30041.1 - 1.4e-05 24.5 0.8 0.097 12.5 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EER30041.1 - 8e-05 22.8 1.9 0.088 13.1 0.4 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.6 EER30041.1 - 0.00085 18.7 2.7 0.00085 18.7 1.9 2.1 2 0 0 2 2 2 1 XPC-binding domain TPR_9 PF13371.1 EER30041.1 - 0.012 15.4 0.6 0.25 11.2 0.4 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 EER30041.1 - 0.036 14.3 0.7 0.098 12.9 0.1 1.9 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 EER30041.1 - 0.92 10.1 4.8 2.8 8.5 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Tim44 PF04280.10 EER30042.1 - 7e-33 113.6 0.0 1.9e-32 112.2 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain Mito_fiss_reg PF05308.6 EER30042.1 - 0.46 9.8 7.3 1 8.6 5.1 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Ribosomal_S11 PF00411.14 EER30043.1 - 3.7e-07 30.3 0.0 5.7e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 Ank_5 PF13857.1 EER30044.1 - 1.1e-16 60.4 0.5 4.4e-13 49.0 0.0 4.8 6 0 0 6 6 6 1 Ankyrin repeats (many copies) VPS9 PF02204.13 EER30044.1 - 2.7e-16 59.4 0.1 6.9e-16 58.1 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EER30044.1 - 2e-11 44.0 0.0 3.8e-07 30.3 0.0 3.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EER30044.1 - 8.9e-08 32.4 0.0 0.003 18.0 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER30044.1 - 8.9e-07 28.5 0.2 0.43 10.9 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 EER30044.1 - 2.5e-05 23.8 3.4 0.021 14.6 0.0 4.9 5 1 0 5 5 5 1 Ankyrin repeat PX PF00787.19 EER30044.1 - 0.00011 22.0 0.4 0.00035 20.3 0.3 1.8 1 0 0 1 1 1 1 PX domain SGT1 PF07093.6 EER30045.1 - 0.023 13.0 4.2 0.033 12.5 2.9 1.2 1 0 0 1 1 1 0 SGT1 protein Herpes_gE PF02480.11 EER30045.1 - 0.052 11.8 0.0 0.052 11.8 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E MGC-24 PF05283.6 EER30045.1 - 0.67 9.7 14.7 1.9 8.2 10.2 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) eIF-3c_N PF05470.7 EER30045.1 - 0.86 7.6 2.4 1.2 7.1 1.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ctr PF04145.10 EER30045.1 - 2.5 8.1 0.0 2.5 8.1 0.0 3.0 4 0 0 4 4 4 0 Ctr copper transporter family Nop14 PF04147.7 EER30045.1 - 4.3 5.1 8.7 6.7 4.4 6.0 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EER30045.1 - 7.9 4.8 14.7 0.097 11.1 4.9 1.6 2 0 0 2 2 2 0 Daxx Family Inhibitor_I78 PF11720.3 EER30046.1 - 7.7e-14 51.1 0.0 1.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EER30046.1 - 0.00028 20.9 0.3 0.0007 19.6 0.2 1.6 1 0 0 1 1 1 1 Potato inhibitor I family Nefa_Nip30_N PF10187.4 EER30047.1 - 2.5e-29 101.4 10.1 5.5e-29 100.3 7.0 1.6 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EER30047.1 - 0.056 12.4 1.4 0.11 11.4 1.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APH PF01636.18 EER30048.1 - 5.3e-05 23.0 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.2 EER30051.1 - 3e-36 123.6 0.4 5.7e-12 45.8 0.1 4.7 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EER30051.1 - 2.7e-28 96.3 16.1 2.6e-07 30.0 0.4 8.0 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EER30051.1 - 1.1e-26 92.2 3.8 0.00011 22.3 0.0 7.8 3 3 4 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EER30051.1 - 4.1e-26 90.8 1.8 2.9e-07 30.7 0.1 6.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EER30051.1 - 1.9e-25 86.3 5.3 0.00011 22.1 0.1 8.3 8 0 0 8 8 8 5 Ankyrin repeat F-box-like PF12937.2 EER30051.1 - 0.071 12.8 0.1 0.23 11.2 0.1 1.9 1 0 0 1 1 1 0 F-box-like vWF_A PF12450.3 EER30051.1 - 0.16 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor Peptidase_S8 PF00082.17 EER30052.1 - 5e-44 150.5 6.1 9.8e-44 149.5 4.2 1.5 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EER30052.1 - 6.5e-17 61.8 0.2 1.6e-16 60.6 0.2 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.17 EER30053.1 - 1.9e-45 155.1 5.2 5.4e-45 153.7 2.1 2.0 1 1 1 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EER30053.1 - 2.8e-15 56.6 0.1 5.2e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 CK_II_beta PF01214.13 EER30055.1 - 3.6e-72 241.7 0.1 5.4e-72 241.1 0.1 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Uso1_p115_C PF04871.8 EER30055.1 - 0.084 12.8 3.3 0.16 11.9 2.3 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ADH_N PF08240.7 EER30056.1 - 3.1e-08 33.3 0.0 5.6e-07 29.3 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EER30056.1 - 6.2e-05 22.5 0.1 0.00012 21.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase E1-E2_ATPase PF00122.15 EER30057.1 - 1.6e-46 158.1 2.0 1.6e-46 158.1 1.4 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EER30057.1 - 2.4e-28 100.0 0.9 5.9e-28 98.7 0.4 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EER30057.1 - 4.8e-13 49.7 0.0 1.8e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EER30057.1 - 2.9e-06 27.3 0.0 6.8e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EER30057.1 - 0.0015 18.1 0.1 0.21 11.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Phage_holin PF04688.8 EER30057.1 - 0.054 13.0 0.2 0.19 11.2 0.1 1.9 1 0 0 1 1 1 0 Phage lysis protein, holin Fungal_trans_2 PF11951.3 EER30058.1 - 5e-12 45.1 0.0 6.6e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EER30058.1 - 3.4e-07 30.0 11.9 6.6e-07 29.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EER30059.1 - 2.7e-05 23.8 0.0 0.00043 19.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF3089 PF11288.3 EER30059.1 - 0.00016 20.9 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_6 PF12697.2 EER30059.1 - 0.0042 16.9 0.1 0.007 16.2 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EER30059.1 - 0.0047 16.6 0.0 0.0071 16.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EER30059.1 - 0.0061 16.1 0.0 0.0086 15.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EER30059.1 - 0.015 15.5 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF915 PF06028.6 EER30059.1 - 0.082 11.9 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.3 EER30059.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 EER30059.1 - 0.16 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) HTH_Tnp_Tc5 PF03221.11 EER30060.1 - 1.3e-12 47.3 0.0 3.3e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EER30060.1 - 1.7e-07 30.6 0.1 3e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EER30060.1 - 0.035 14.1 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain UPF0175 PF03683.8 EER30060.1 - 0.091 12.2 0.0 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) JAB PF01398.16 EER30061.1 - 3.8e-07 29.8 0.1 2e-05 24.2 0.1 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HMG_box PF00505.14 EER30063.1 - 1e-09 38.4 0.5 1e-09 38.4 0.3 3.2 3 1 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EER30063.1 - 3.9e-05 23.9 0.6 3.9e-05 23.9 0.4 3.5 3 1 1 4 4 4 2 HMG-box domain Xylo_C PF12529.3 EER30063.1 - 0.22 10.8 1.7 0.85 8.9 0.2 2.3 2 0 0 2 2 2 0 Xylosyltransferase C terminal YABBY PF04690.8 EER30063.1 - 0.56 10.4 8.2 0.18 12.0 1.4 2.3 2 0 0 2 2 2 0 YABBY protein DEAD PF00270.24 EER30064.1 - 4.4e-46 156.4 0.0 8.2e-46 155.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EER30064.1 - 7.6e-25 86.5 0.0 2.4e-24 84.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EER30064.1 - 0.00027 19.8 0.0 0.00048 19.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EER30064.1 - 0.033 14.0 0.0 0.21 11.4 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Abhydrolase_5 PF12695.2 EER30064.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-C2H2 PF00096.21 EER30066.1 - 2.4e-15 55.8 34.5 4.2e-07 29.9 1.7 6.9 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EER30066.1 - 1.4e-13 50.4 32.3 2.9e-07 30.4 1.8 5.5 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EER30066.1 - 1e-11 44.6 4.1 0.00016 21.7 0.6 4.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EER30066.1 - 9.9e-09 35.1 6.8 0.0026 17.9 0.0 5.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EER30066.1 - 2.7e-08 33.5 6.2 4.1e-05 23.6 0.3 7.5 8 0 0 8 8 8 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EER30066.1 - 8e-06 25.5 6.2 0.0061 16.4 0.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger TraG-D_C PF12696.2 EER30067.1 - 0.026 14.4 0.2 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Phage_DsbA PF11126.3 EER30067.1 - 0.042 13.9 0.2 0.072 13.1 0.2 1.3 1 0 0 1 1 1 0 Transcriptional regulator DsbA AMP-binding PF00501.23 EER30068.1 - 5.5e-83 278.6 0.0 6.8e-83 278.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EER30068.1 - 2.4e-09 38.0 0.0 7.8e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Kelch_6 PF13964.1 EER30070.1 - 1.1e-05 25.4 1.6 0.54 10.5 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 EER30070.1 - 0.068 13.1 3.2 13 5.8 0.1 4.3 4 0 0 4 4 4 0 Kelch motif DUF1180 PF06679.7 EER30070.1 - 0.39 10.5 0.1 0.39 10.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) TPR_14 PF13428.1 EER30071.1 - 1.7e-23 80.9 19.2 0.0036 17.7 0.0 11.8 5 2 7 12 12 12 7 Tetratricopeptide repeat HAT PF02184.11 EER30071.1 - 5.4e-23 80.4 79.9 1.3e-14 53.5 3.3 13.6 15 0 0 15 15 15 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EER30071.1 - 4.7e-21 74.8 0.0 0.0022 18.3 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EER30071.1 - 1.4e-17 63.8 14.8 0.012 16.2 0.0 8.3 8 1 2 10 10 10 6 Tetratricopeptide repeat Suf PF05843.9 EER30071.1 - 3.5e-15 56.4 20.9 0.00086 19.1 0.4 6.2 2 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_15 PF13429.1 EER30071.1 - 4.9e-06 25.8 17.9 0.025 13.6 1.8 5.4 2 2 2 5 5 5 3 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EER30071.1 - 8.6e-06 25.4 35.0 0.018 14.8 1.5 7.5 6 2 1 8 8 8 4 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.12 EER30071.1 - 1.8e-05 24.2 15.2 3.2 7.9 0.0 9.1 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 EER30071.1 - 5.9e-05 22.9 0.5 7.6 7.0 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat NRDE-2 PF08424.5 EER30071.1 - 0.00093 18.1 1.9 0.00093 18.1 1.3 6.6 3 3 3 6 6 6 2 NRDE-2, necessary for RNA interference SNase PF00565.12 EER30071.1 - 0.023 14.9 1.4 0.41 10.9 0.2 2.8 3 0 0 3 3 2 0 Staphylococcal nuclease homologue TPR_6 PF13174.1 EER30071.1 - 0.047 14.1 21.5 6.5 7.4 0.0 8.4 9 1 1 10 10 9 0 Tetratricopeptide repeat Prp31_C PF09785.4 EER30072.1 - 1.8e-44 151.1 1.0 3.2e-44 150.3 0.7 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EER30072.1 - 2.1e-41 140.7 0.0 4e-41 139.8 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EER30072.1 - 4.6e-21 74.3 0.4 1.5e-20 72.7 0.1 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain Spore_YtrH PF14034.1 EER30072.1 - 0.07 13.0 0.5 0.4 10.6 0.1 2.4 4 0 0 4 4 4 0 Sporulation protein YtrH AdoHcyase PF05221.12 EER30073.1 - 3.5e-137 455.7 0.1 4e-137 455.5 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EER30073.1 - 7e-84 279.5 1.5 1.2e-83 278.8 1.1 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EER30073.1 - 5e-07 29.0 0.1 1e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EER30073.1 - 0.0016 18.1 0.1 0.0026 17.3 0.1 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 EER30073.1 - 0.0032 16.8 0.1 0.0058 16.0 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EER30073.1 - 0.0048 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EER30073.1 - 0.077 12.9 0.6 11 5.9 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase zf-H2C2_2 PF13465.1 EER30074.1 - 1.3e-08 34.6 12.0 1.1e-07 31.7 0.7 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EER30074.1 - 5.3e-06 26.3 5.6 0.00012 22.1 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EER30074.1 - 3.2e-05 23.9 0.8 3.2e-05 23.9 0.5 3.8 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EER30074.1 - 0.12 12.3 6.1 0.98 9.4 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EER30074.1 - 0.68 10.1 7.2 0.64 10.2 0.2 3.6 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.18 EER30075.1 - 2.1e-66 223.7 0.1 3.2e-66 223.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EER30075.1 - 7.3e-23 79.9 1.7 3.7e-12 45.7 0.2 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EER30075.1 - 3.2e-18 65.8 0.1 6.9e-17 61.5 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EER30075.1 - 2.5e-12 46.4 0.0 6.7e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EER30075.1 - 9.6e-06 25.5 2.7 0.00023 21.0 0.0 3.8 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EER30075.1 - 0.057 13.5 0.0 0.46 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EER30076.1 - 1.2e-36 125.9 0.0 1.9e-17 63.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EER30076.1 - 1.8e-14 54.4 8.3 0.00057 19.9 0.0 4.6 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 EER30076.1 - 4.8e-11 42.2 4.9 0.0012 18.1 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EER30076.1 - 4.7e-07 29.1 0.1 1.7 7.5 0.0 4.5 4 1 1 5 5 5 2 AAA ATPase domain AAA_17 PF13207.1 EER30076.1 - 2.1e-05 25.3 0.9 0.45 11.3 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EER30076.1 - 4.7e-05 23.5 0.1 0.056 13.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EER30076.1 - 5.4e-05 23.3 0.0 0.028 14.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EER30076.1 - 0.00017 20.8 0.0 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EER30076.1 - 0.00024 21.3 0.2 0.39 11.0 0.0 3.3 3 1 0 3 3 2 1 AAA domain Miro PF08477.8 EER30076.1 - 0.00042 20.7 0.1 0.079 13.4 0.0 3.1 3 0 0 3 3 3 1 Miro-like protein AAA_33 PF13671.1 EER30076.1 - 0.00063 19.6 0.0 0.075 12.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EER30076.1 - 0.001 18.7 1.7 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 EER30076.1 - 0.0016 17.9 0.1 1.6 8.1 0.0 2.6 2 0 0 2 2 2 2 Virulence-associated protein E AAA_29 PF13555.1 EER30076.1 - 0.0019 17.6 1.6 1.6 8.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 EER30076.1 - 0.0019 18.3 0.1 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Rad17 PF03215.10 EER30076.1 - 0.0024 16.6 0.0 0.06 12.0 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EER30076.1 - 0.0026 18.1 0.1 0.27 11.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EER30076.1 - 0.003 17.1 0.6 0.03 13.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EER30076.1 - 0.0051 16.4 2.4 0.41 10.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.17 EER30076.1 - 0.0064 15.9 3.9 0.1 12.0 0.1 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EER30076.1 - 0.0064 16.4 0.3 0.9 9.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.1 EER30076.1 - 0.0094 14.4 1.2 0.013 14.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EER30076.1 - 0.01 15.2 2.0 1.3 8.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain KaiC PF06745.8 EER30076.1 - 0.041 13.0 0.1 0.098 11.7 0.0 1.6 1 0 0 1 1 1 0 KaiC DLIC PF05783.6 EER30076.1 - 0.047 12.3 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Thymidylate_kin PF02223.12 EER30076.1 - 0.048 13.0 1.2 7.8 5.8 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase AAA_28 PF13521.1 EER30076.1 - 0.052 13.5 0.1 5.6 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EER30076.1 - 0.082 12.6 0.2 7 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EER30076.1 - 0.085 12.4 0.6 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EER30076.1 - 0.097 12.2 2.8 0.4 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EER30076.1 - 0.1 12.1 2.9 0.12 11.8 0.0 2.5 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EER30076.1 - 0.14 12.0 1.7 8.7 6.2 0.1 3.3 2 2 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EER30076.1 - 0.27 10.0 3.1 9.4 4.9 0.2 2.6 2 1 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EER30076.1 - 0.52 9.9 2.4 22 4.7 0.1 2.6 2 0 0 2 2 2 0 NTPase FF PF01846.14 EER30077.1 - 2.5e-42 142.6 17.8 2.6e-13 49.7 0.1 6.8 6 0 0 6 6 6 5 FF domain WW PF00397.21 EER30077.1 - 7.9e-18 63.9 8.4 3.4e-08 33.1 0.2 2.9 2 0 0 2 2 2 2 WW domain Trs65 PF12735.2 EER30078.1 - 6.1e-63 212.9 0.1 1.1e-62 212.1 0.0 1.4 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 DUF2671 PF10877.3 EER30078.1 - 0.16 11.7 0.0 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2671) Mpv17_PMP22 PF04117.7 EER30079.1 - 2.6e-21 74.9 0.2 2.6e-21 74.9 0.1 2.1 3 0 0 3 3 3 1 Mpv17 / PMP22 family DSS1_SEM1 PF05160.8 EER30080.1 - 3.1e-20 71.7 12.9 3.9e-20 71.3 9.0 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF1762 PF08574.5 EER30080.1 - 0.46 10.9 4.1 12 6.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1762) PGK PF00162.14 EER30081.1 - 9.8e-151 501.6 0.4 1.1e-150 501.4 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 EER30081.1 - 0.034 13.5 0.3 2.6 7.4 0.1 3.0 3 0 0 3 3 3 0 Propionate catabolism activator DUF3530 PF12048.3 EER30081.1 - 0.048 12.6 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3530)