# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Mitofilin PF09731.9 EEQ35878.1 - 1.6e-48 166.0 39.5 6.4e-48 164.0 26.4 2.9 1 1 2 3 3 3 2 Mitochondrial inner membrane protein DASH_Dad1 PF08649.10 EEQ35878.1 - 0.00045 20.3 4.8 0.0052 16.9 0.5 3.1 2 0 0 2 2 2 1 DASH complex subunit Dad1 Tht1 PF04163.12 EEQ35878.1 - 0.058 12.1 12.4 0.12 11.2 12.4 1.5 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein PI3K_P85_iSH2 PF16454.5 EEQ35878.1 - 0.098 12.2 23.5 0.013 15.1 13.3 2.9 2 1 2 4 4 4 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 EEQ35878.1 - 1.8 7.9 9.5 5 6.4 9.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phasin PF05597.11 EEQ35878.1 - 3.3 7.7 16.7 2.1 8.4 5.3 3.8 2 2 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Actin PF00022.19 EEQ35879.1 - 9.9e-112 373.5 0.0 1.3e-111 373.1 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEQ35879.1 - 0.00012 21.0 0.0 0.14 11.0 0.1 2.5 2 1 0 2 2 2 2 MreB/Mbl protein 2-oxogl_dehyd_N PF16078.5 EEQ35879.1 - 0.057 13.0 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Clathrin PF00637.20 EEQ35879.1 - 0.076 12.9 0.5 0.87 9.4 0.1 2.1 2 0 0 2 2 2 0 Region in Clathrin and VPS ArenaCapSnatch PF17296.2 EEQ35879.1 - 0.16 11.4 0.0 0.38 10.2 0.0 1.5 1 0 0 1 1 1 0 Arenavirus cap snatching domain WD40 PF00400.32 EEQ35880.1 - 8e-29 99.3 20.8 4.4e-05 24.2 0.1 9.4 9 1 1 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ35880.1 - 3.3e-16 59.3 0.1 0.0063 16.8 0.0 6.1 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EEQ35880.1 - 0.0001 22.1 0.9 1.1 9.3 0.0 5.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Me-amine-dh_H PF06433.11 EEQ35880.1 - 0.005 15.8 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 Methylamine dehydrogenase heavy chain (MADH) Coatomer_WDAD PF04053.14 EEQ35880.1 - 0.0081 15.3 0.3 0.76 8.7 0.0 2.6 3 0 0 3 3 3 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 EEQ35880.1 - 0.016 13.8 0.1 5.4 5.4 0.0 2.5 2 1 0 2 2 2 0 Cytochrome D1 heme domain Lactonase PF10282.9 EEQ35880.1 - 0.017 14.4 0.2 0.56 9.4 0.0 3.2 4 0 0 4 4 4 0 Lactonase, 7-bladed beta-propeller CPSF_A PF03178.15 EEQ35880.1 - 0.041 13.2 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 CPSF A subunit region WD40_like PF17005.5 EEQ35880.1 - 0.098 12.0 0.2 3.5 6.9 0.0 3.0 3 1 0 3 3 3 0 WD40-like domain Alpha-amylase PF00128.24 EEQ35881.1 - 9.3e-16 58.3 0.4 2.4e-14 53.6 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EEQ35881.1 - 2e-13 50.5 0.1 4.2e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Apolipoprotein PF01442.18 EEQ35882.1 - 0.0072 16.2 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Imm42 PF15593.6 EEQ35883.1 - 0.31 11.5 3.6 0.46 10.9 3.6 1.2 1 0 0 1 1 1 0 Immunity protein 42 Ku PF02735.16 EEQ35884.1 - 1.3e-18 67.5 1.5 2.3e-18 66.7 1.5 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Hs1pro-1_N PF07231.12 EEQ35884.1 - 0.022 14.5 0.1 0.04 13.7 0.1 1.4 1 0 0 1 1 1 0 Hs1pro-1 N-terminus MMR_HSR1 PF01926.23 EEQ35885.1 - 1.1e-13 51.2 0.0 3.2e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ35885.1 - 7e-05 22.8 0.8 0.0002 21.3 0.2 2.1 2 1 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EEQ35885.1 - 0.0003 20.4 1.2 0.0064 16.0 0.4 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B AIG1 PF04548.16 EEQ35885.1 - 0.012 14.9 0.9 0.048 13.0 0.1 2.2 2 1 1 3 3 3 0 AIG1 family GTP_EFTU PF00009.27 EEQ35885.1 - 0.037 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EEQ35885.1 - 0.11 13.1 0.3 0.38 11.3 0.1 2.0 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EEQ35886.1 - 2.1e-99 332.4 0.0 2.4e-99 332.2 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EEQ35886.1 - 0.00016 21.8 0.4 0.00077 19.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ35886.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EEQ35886.1 - 0.021 15.3 0.2 2.8 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EEQ35886.1 - 0.12 12.1 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.20 EEQ35886.1 - 0.16 11.9 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Adenylylsulphate kinase Utp11 PF03998.13 EEQ35887.1 - 5.8e-67 226.2 40.6 6.6e-67 226.0 40.6 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EEQ35887.1 - 0.014 14.7 0.5 0.014 14.7 0.5 2.5 2 1 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Saw1 PF11561.8 EEQ35887.1 - 9.9 5.6 18.2 8.2 5.9 17.2 1.4 1 1 0 1 1 1 0 Single strand annealing-weakened 1 RsfS PF02410.15 EEQ35888.1 - 2.7e-16 59.8 0.0 5.6e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation mRNA_stabil PF13929.6 EEQ35888.1 - 0.00048 19.2 0.8 0.0054 15.8 0.1 2.1 2 0 0 2 2 2 1 mRNA stabilisation Endotoxin_C2 PF18449.1 EEQ35888.1 - 0.025 14.9 0.1 0.07 13.5 0.1 1.7 1 0 0 1 1 1 0 Delta endotoxin SLATT_1 PF18181.1 EEQ35888.1 - 0.043 13.7 0.1 0.089 12.7 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 1 Drc1-Sld2 PF11719.8 EEQ35889.1 - 1.3e-67 229.3 37.5 2e-67 228.7 37.5 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein zf-C2HC5 PF06221.13 EEQ35890.1 - 3.2e-23 81.5 6.6 5.4e-23 80.7 6.6 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.6 EEQ35890.1 - 1.7 8.2 5.6 4.5 6.8 5.7 1.7 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EEQ35890.1 - 2.2 8.1 5.3 8.5 6.2 5.3 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-CCCH PF00642.24 EEQ35891.1 - 5.2e-19 67.7 21.6 6.2e-06 26.0 1.5 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ35891.1 - 1.6e-10 40.7 32.2 0.0003 20.7 3.2 5.5 5 1 0 5 5 5 4 Zinc finger domain Torus PF16131.5 EEQ35891.1 - 0.00029 21.5 26.6 0.045 14.5 0.8 5.3 2 2 4 6 6 6 3 Torus domain zf-CCCH_4 PF18044.1 EEQ35891.1 - 0.0016 18.2 30.5 0.84 9.5 0.7 5.8 5 1 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EEQ35891.1 - 0.009 16.4 2.1 0.009 16.4 2.1 4.8 5 0 0 5 5 5 2 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 EEQ35891.1 - 0.027 14.2 0.3 0.027 14.2 0.3 4.4 4 0 0 4 4 4 0 Putative zinc-finger domain DUF5643 PF18705.1 EEQ35891.1 - 0.22 11.5 2.0 0.18 11.8 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5643) CART PF06373.11 EEQ35891.1 - 2.4 8.4 7.6 0.72 10.1 0.5 3.0 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) zf-CCCH_3 PF15663.5 EEQ35891.1 - 3.6 7.8 14.3 15 5.8 6.6 3.7 1 1 1 3 3 3 0 Zinc-finger containing family Pkinase PF00069.25 EEQ35892.1 - 2.7e-46 158.1 0.0 5e-46 157.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35892.1 - 2.2e-24 86.2 0.0 6.9e-23 81.2 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EEQ35892.1 - 0.008 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEQ35892.1 - 0.094 11.5 0.0 0.18 10.5 0.0 1.5 1 1 1 2 2 2 0 Fungal protein kinase TANGO2 PF05742.12 EEQ35893.1 - 9.6e-72 242.1 0.0 1.1e-71 241.9 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 LIDHydrolase PF10230.9 EEQ35894.1 - 6.1e-62 209.6 0.2 7.2e-62 209.3 0.2 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase DUF900 PF05990.12 EEQ35894.1 - 0.00015 21.4 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) MOZART2 PF12926.7 EEQ35894.1 - 0.0041 16.7 0.0 0.008 15.8 0.0 1.4 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated Hydrolase_4 PF12146.8 EEQ35894.1 - 0.044 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ35894.1 - 0.085 13.4 0.0 0.12 12.9 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.16 EEQ35895.1 - 4.2e-37 127.9 19.5 5.7e-37 127.4 19.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.26 EEQ35896.1 - 8.7e-12 45.2 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ35896.1 - 0.00012 21.9 0.1 0.001 18.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EEQ35896.1 - 0.011 16.7 0.1 0.077 14.1 0.1 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 EEQ35896.1 - 0.03 14.6 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_25 PF13649.6 EEQ35897.1 - 8.4e-13 48.9 0.1 6.2e-12 46.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EEQ35897.1 - 1.5e-11 44.2 0.0 2.2e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EEQ35897.1 - 3e-11 43.4 0.1 9.6e-11 41.7 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ35897.1 - 9.6e-10 39.0 0.0 4.5e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EEQ35897.1 - 4.9e-07 29.0 0.1 8.4e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EEQ35897.1 - 6.9e-07 29.2 0.0 1e-06 28.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ35897.1 - 3.2e-05 23.6 0.1 5.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EEQ35897.1 - 3.3e-05 23.3 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EEQ35897.1 - 3.8e-05 23.7 0.1 6.4e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ35897.1 - 0.00014 22.5 0.0 0.00031 21.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EEQ35897.1 - 0.0036 17.1 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 EEQ35897.1 - 0.0091 16.1 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 EEQ35897.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EEQ35897.1 - 0.031 13.7 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Tellurite resistance protein TehB PRMT5 PF05185.16 EEQ35897.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 EEQ35897.1 - 0.091 13.8 0.0 0.17 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EEQ35897.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EEQ35897.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 SelR PF01641.18 EEQ35898.1 - 1.4e-47 160.7 0.1 1.6e-47 160.5 0.1 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EEQ35898.1 - 0.16 12.2 2.5 0.42 10.8 2.5 1.7 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 EEQ35898.1 - 0.45 10.6 4.2 1.7 8.7 0.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon Steroid_dh PF02544.16 EEQ35899.1 - 2.5e-21 76.3 6.3 2.5e-21 76.3 6.3 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase MBF1 PF08523.10 EEQ35900.1 - 2.3e-24 85.6 1.0 2.3e-24 85.6 1.0 1.9 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EEQ35900.1 - 6.3e-14 51.8 0.2 1.3e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.7 EEQ35900.1 - 9.2e-06 25.6 0.2 1.7e-05 24.8 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.6 EEQ35900.1 - 1.1e-05 25.7 0.2 3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain Ras PF00071.22 EEQ35901.1 - 2.8e-53 179.8 0.0 4.2e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ35901.1 - 4.1e-37 127.1 0.0 5.7e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ35901.1 - 5.9e-17 61.7 0.0 7.2e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ35901.1 - 2.2e-07 30.4 0.0 2.8e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ35901.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ35901.1 - 4.9e-06 26.2 0.0 6.6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ35901.1 - 0.0033 17.4 0.3 0.31 10.9 0.0 2.3 1 1 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EEQ35901.1 - 0.0042 17.5 0.1 0.0092 16.4 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ35901.1 - 0.015 15.5 0.0 6.9 6.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain TniB PF05621.11 EEQ35901.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 EEQ35901.1 - 0.031 13.4 0.1 0.13 11.3 0.1 1.8 1 1 0 1 1 1 0 G-protein alpha subunit BP28CT PF08146.12 EEQ35902.1 - 5.4e-40 136.8 2.6 3.7e-39 134.1 0.5 2.6 3 0 0 3 3 3 1 BP28CT (NUC211) domain DRIM PF07539.12 EEQ35902.1 - 2.4e-07 29.5 1.3 0.00062 18.2 0.0 3.2 2 1 1 3 3 3 3 Down-regulated in metastasis DUF3385 PF11865.8 EEQ35902.1 - 7.5e-06 25.9 1.2 0.038 13.9 0.1 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF3385) Tti2 PF10521.9 EEQ35902.1 - 0.0016 18.0 2.1 0.72 9.3 0.5 3.1 2 1 1 3 3 3 2 Tti2 family CENP-B_dimeris PF09026.10 EEQ35902.1 - 0.013 15.9 0.0 0.013 15.9 0.0 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HEAT_2 PF13646.6 EEQ35902.1 - 0.02 15.3 0.0 1.1 9.6 0.0 2.9 3 0 0 3 3 3 0 HEAT repeats PUB PF09409.10 EEQ35902.1 - 0.1 12.6 0.7 0.48 10.4 0.4 2.3 2 0 0 2 2 2 0 PUB domain U3snoRNP10 PF12397.8 EEQ35903.1 - 2.5e-12 47.2 0.2 2.5e-12 47.2 0.2 3.4 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 AA_permease PF00324.21 EEQ35904.1 - 1e-120 403.6 45.3 1.3e-120 403.3 45.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ35904.1 - 3.6e-31 108.4 47.1 5e-31 108.0 47.1 1.1 1 0 0 1 1 1 1 Amino acid permease Rad54_N PF08658.10 EEQ35905.1 - 4.6 7.4 13.9 3.3 7.8 11.8 1.7 2 0 0 2 2 2 0 Rad54 N terminal Peptidase_C1_2 PF03051.15 EEQ35906.1 - 5.2e-152 506.6 3.1 5.9e-152 506.5 3.1 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EEQ35906.1 - 3.4e-05 24.0 2.5 0.011 15.9 1.5 3.3 3 1 0 3 3 3 2 Papain family cysteine protease Ribosomal_S8e PF01201.22 EEQ35907.1 - 7.9e-58 194.5 2.3 9.6e-58 194.2 2.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.13 EEQ35908.1 - 2.3e-20 72.1 0.1 2.7e-20 71.8 0.1 1.1 1 0 0 1 1 1 1 CSL zinc finger Prok-RING_1 PF14446.6 EEQ35908.1 - 0.074 13.0 2.2 0.13 12.2 2.2 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Myb_DNA-binding PF00249.31 EEQ35909.1 - 2.2e-27 95.0 0.9 9.9e-15 54.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ35909.1 - 1.8e-18 66.5 1.5 2.3e-12 46.9 0.0 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain tRNA_int_endo PF01974.17 EEQ35910.1 - 2.5e-16 59.5 0.0 4.2e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain PNGaseA PF12222.8 EEQ35911.1 - 3.3e-112 375.5 0.0 4.5e-112 375.1 0.0 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Vps35 PF03635.17 EEQ35912.1 - 4.5e-262 871.8 25.8 5.2e-262 871.6 25.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 NPH3 PF03000.14 EEQ35912.1 - 0.00038 20.2 0.7 0.0025 17.5 0.6 2.6 1 1 1 2 2 2 1 NPH3 family ATG2_CAD PF13329.6 EEQ35913.1 - 1.6e-38 131.9 1.2 4e-38 130.6 0.1 2.4 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EEQ35913.1 - 4.3e-29 100.7 1.3 9.5e-28 96.4 0.1 2.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EEQ35913.1 - 7.8e-05 22.5 1.6 0.00047 20.0 0.0 3.2 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal SIMPL PF04402.14 EEQ35913.1 - 0.049 14.1 0.2 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF541) Helicase_IV_N PF12462.8 EEQ35913.1 - 0.066 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal T2SSppdC PF12528.8 EEQ35913.1 - 0.28 12.0 0.9 1.1 10.1 0.1 2.3 3 0 0 3 3 3 0 Type II secretion prepilin peptidase dependent protein C Las1 PF04031.13 EEQ35914.1 - 4.2e-46 156.9 0.4 6.6e-46 156.2 0.4 1.3 1 0 0 1 1 1 1 Las1-like GxGYxYP_N PF16216.5 EEQ35914.1 - 0.02 15.1 0.0 3 8.0 0.0 2.3 1 1 1 2 2 2 0 GxGYxY sequence motif in domain of unknown function N-terminal DUF953 PF06110.11 EEQ35914.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Gpr1_Fun34_YaaH PF01184.19 EEQ35915.1 - 5e-81 271.2 23.4 5.8e-81 271.0 23.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BIV_Env PF05858.12 EEQ35916.1 - 0.034 12.4 0.2 0.034 12.4 0.2 1.5 2 0 0 2 2 2 0 Bovine immunodeficiency virus surface protein (SU) CDC14 PF08045.11 EEQ35917.1 - 4.3e-24 85.1 0.0 5.7e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component DUF1116 PF06545.11 EEQ35917.1 - 0.044 13.2 0.1 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) MDM10 PF12519.8 EEQ35918.1 - 9.5e-152 506.1 5.2 1.1e-151 505.9 5.2 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Mit_ribos_Mrp51 PF11709.8 EEQ35919.1 - 4.2e-61 207.5 7.8 5.9e-36 124.8 2.0 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein subunit PAH PF02671.21 EEQ35919.1 - 0.14 12.3 0.1 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 Paired amphipathic helix repeat PBP1_TM PF14812.6 EEQ35920.1 - 6.7 7.2 10.1 23 5.4 10.1 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 EEQ35921.1 - 2.3e-63 214.1 0.0 3.6e-63 213.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35921.1 - 4e-49 167.2 0.0 6.7e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ35921.1 - 5.5e-07 28.7 2.7 3.2e-06 26.2 0.0 2.7 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EEQ35921.1 - 1.1e-05 24.9 0.7 3e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EEQ35921.1 - 0.019 14.6 0.0 0.052 13.1 0.0 1.6 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 EEQ35921.1 - 0.026 14.4 0.0 0.076 12.9 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EEQ35921.1 - 0.076 12.4 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEQ35921.1 - 0.091 11.7 0.0 0.091 11.7 0.0 3.7 4 0 0 4 4 4 0 Haspin like kinase domain FTA2 PF13095.6 EEQ35921.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 IGPD PF00475.18 EEQ35922.1 - 8.1e-60 201.3 0.5 1.3e-59 200.7 0.5 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase SpoU_methylase PF00588.19 EEQ35923.1 - 1.7e-24 86.6 0.0 3.8e-24 85.5 0.0 1.6 2 0 0 2 2 2 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EEQ35923.1 - 1.4e-16 60.5 0.0 3.8e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF676 PF05057.14 EEQ35924.1 - 4e-42 144.2 0.0 6.3e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EEQ35924.1 - 5e-06 26.5 0.0 7.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EEQ35924.1 - 0.00038 20.2 0.1 0.0014 18.4 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EEQ35924.1 - 0.00096 18.5 0.0 0.085 12.1 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 EEQ35924.1 - 0.0016 18.3 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 EEQ35924.1 - 0.0039 16.4 0.0 0.0074 15.5 0.0 1.5 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EEQ35924.1 - 0.0055 17.3 0.0 0.009 16.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ35924.1 - 0.05 13.3 0.1 0.5 10.0 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 EEQ35924.1 - 0.086 12.2 0.1 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Ysc84 PF04366.12 EEQ35925.1 - 2.2e-42 143.8 0.6 3.3e-42 143.2 0.6 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EEQ35925.1 - 9.3e-16 57.2 0.1 1.7e-15 56.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ35925.1 - 4.7e-12 45.4 0.0 8.9e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EEQ35925.1 - 7e-12 45.0 0.0 1.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arm PF00514.23 EEQ35926.1 - 4.2e-75 245.7 26.8 2.3e-12 46.5 0.0 11.3 11 1 1 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EEQ35926.1 - 1.1e-23 83.2 11.5 0.00023 21.6 0.3 8.7 10 0 0 10 10 9 5 HEAT-like repeat HEAT_2 PF13646.6 EEQ35926.1 - 1.3e-16 60.7 11.1 0.0064 16.9 0.3 7.0 5 1 2 8 8 7 5 HEAT repeats Adaptin_N PF01602.20 EEQ35926.1 - 2.5e-14 52.8 4.5 1.6e-08 33.6 1.3 2.2 1 1 1 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 EEQ35926.1 - 5.2e-13 48.0 22.1 0.029 14.6 0.1 9.6 11 0 0 11 11 9 4 HEAT repeat KAP PF05804.12 EEQ35926.1 - 6.8e-10 37.7 0.2 9.9e-07 27.3 0.0 2.2 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) Arm_2 PF04826.13 EEQ35926.1 - 1.2e-09 38.0 10.5 3.7e-06 26.6 2.3 3.4 2 1 2 4 4 4 3 Armadillo-like V-ATPase_H_C PF11698.8 EEQ35926.1 - 8.3e-07 29.1 2.1 0.047 13.8 0.0 4.9 3 1 4 7 7 7 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 EEQ35926.1 - 1.4e-05 24.5 2.7 0.13 11.5 0.2 3.6 1 1 2 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EEQ35926.1 - 2.8e-05 24.2 7.9 0.15 12.1 0.3 4.9 1 1 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEQ35926.1 - 0.00019 22.0 0.3 0.9 10.2 0.0 3.4 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region DUF5578 PF17741.1 EEQ35926.1 - 0.00021 20.8 4.4 0.4 10.1 0.0 4.5 2 1 4 6 6 6 1 Family of unknown function (DUF5578) RTP1_C1 PF10363.9 EEQ35926.1 - 0.0033 17.6 1.1 10 6.4 0.0 4.5 4 1 1 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Tti2 PF10521.9 EEQ35926.1 - 0.058 12.9 0.1 12 5.3 0.0 3.2 3 0 0 3 3 3 0 Tti2 family Snf7 PF03357.21 EEQ35927.1 - 3.5e-21 75.5 13.8 3.5e-21 75.5 13.8 1.6 1 1 1 2 2 2 1 Snf7 CorA PF01544.18 EEQ35927.1 - 2.2 7.5 9.3 4.6 6.5 8.8 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ParA PF10609.9 EEQ35928.1 - 5.2e-94 314.3 0.0 6.1e-94 314.1 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EEQ35928.1 - 2e-09 37.6 0.0 4.2e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EEQ35928.1 - 2.7e-05 24.2 0.0 0.00026 21.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EEQ35928.1 - 0.00023 20.5 0.0 0.00048 19.5 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EEQ35928.1 - 0.00027 20.2 0.3 0.0062 15.8 0.0 2.3 2 1 0 2 2 2 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 EEQ35928.1 - 0.01 15.8 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_26 PF13500.6 EEQ35928.1 - 0.016 15.1 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 EEQ35928.1 - 0.035 13.6 0.0 0.28 10.6 0.0 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ TF_Zn_Ribbon PF08271.12 EEQ35928.1 - 0.059 12.9 0.4 0.13 11.8 0.4 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding NB-ARC PF00931.22 EEQ35928.1 - 0.079 12.1 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 EEQ35928.1 - 0.087 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EEQ35928.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Nup96 PF12110.8 EEQ35929.1 - 9.5e-36 123.4 0.4 6.8e-17 61.5 0.1 3.3 2 1 0 3 3 3 2 Nuclear protein 96 Nucleoporin2 PF04096.14 EEQ35929.1 - 4.4e-35 121.0 0.0 1.1e-34 119.7 0.0 1.8 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EEQ35929.1 - 8.6e-21 74.6 115.6 1.9e-09 38.2 34.5 4.7 1 1 3 4 4 4 4 Nucleoporin FG repeat region SPG4 PF17325.2 EEQ35929.1 - 0.46 11.6 3.3 0.88 10.7 0.3 3.2 2 0 0 2 2 2 0 Stationary phase protein 4 YjeF_N PF03853.15 EEQ35930.1 - 1.8e-30 106.1 0.0 3.8e-30 105.0 0.0 1.6 1 1 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EEQ35930.1 - 1.1e-09 39.2 0.9 1.1e-09 39.2 0.9 1.8 2 0 0 2 2 2 1 FDF domain LSM PF01423.22 EEQ35930.1 - 0.13 12.0 0.1 0.5 10.1 0.0 2.0 2 0 0 2 2 2 0 LSM domain partial_CstF PF15861.5 EEQ35930.1 - 0.13 12.1 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain pPIWI_RE_Y PF18156.1 EEQ35930.1 - 0.17 12.3 0.0 0.28 11.6 0.0 1.3 1 0 0 1 1 1 0 pPIWI_RE three-gene island domain Y Kinesin PF00225.23 EEQ35931.1 - 6e-95 318.0 0.0 9e-95 317.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ35931.1 - 7.8e-23 81.1 0.0 6.2e-22 78.1 0.0 2.5 3 0 0 3 3 3 1 Microtubule binding TPR_MLP1_2 PF07926.12 EEQ35931.1 - 0.00045 20.3 13.1 0.00083 19.4 7.3 2.7 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein TSC22 PF01166.18 EEQ35931.1 - 0.0046 17.2 6.4 1.6 9.1 0.4 3.6 3 0 0 3 3 3 2 TSC-22/dip/bun family SlyX PF04102.12 EEQ35931.1 - 0.0065 17.1 9.8 0.057 14.0 0.9 3.3 1 1 2 3 3 3 2 SlyX DUF4792 PF16040.5 EEQ35931.1 - 0.0076 16.1 0.4 0.048 13.6 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4792) YvfG PF09628.10 EEQ35931.1 - 0.069 13.5 0.1 0.26 11.7 0.1 2.0 1 0 0 1 1 1 0 YvfG protein Phage_GP20 PF06810.11 EEQ35931.1 - 0.07 12.9 5.6 0.084 12.7 1.6 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 HALZ PF02183.18 EEQ35931.1 - 0.13 12.5 2.0 12 6.2 0.1 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 EEQ35931.1 - 0.3 11.1 9.9 0.93 9.5 9.7 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MIP-T3_C PF17749.1 EEQ35931.1 - 1.3 9.0 11.6 2.5 8.0 11.6 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region DUF4407 PF14362.6 EEQ35931.1 - 2 7.7 6.2 4.4 6.6 6.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 EEQ35931.1 - 3 8.8 11.6 0.28 12.1 5.6 2.4 3 0 0 3 3 2 0 cGMP-dependent protein kinase interacting domain DUF87 PF01935.17 EEQ35931.1 - 5.4 7.0 7.5 23 5.0 0.2 3.1 2 1 0 2 2 2 0 Helicase HerA, central domain YabA PF06156.13 EEQ35931.1 - 8.4 7.1 12.0 64 4.3 1.6 3.9 3 1 1 4 4 4 0 Initiation control protein YabA UBX PF00789.20 EEQ35932.1 - 3.7e-05 23.9 0.0 0.00053 20.1 0.0 2.7 3 0 0 3 3 3 1 UBX domain Prok-RING_4 PF14447.6 EEQ35933.1 - 0.062 13.2 1.0 0.16 11.9 1.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PALP PF00291.25 EEQ35934.1 - 1.6e-67 228.0 0.0 2.1e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EEQ35934.1 - 2e-10 41.0 0.0 6.8e-07 29.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain E3_binding PF02817.17 EEQ35934.1 - 0.042 14.2 0.2 16 5.9 0.1 2.7 2 0 0 2 2 2 0 e3 binding domain Zeta_toxin PF06414.12 EEQ35934.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin PBP-Tp47_a PF14889.6 EEQ35934.1 - 0.07 12.8 0.0 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Penicillin-binding protein Tp47 domain a TFIIS_M PF07500.14 EEQ35935.1 - 6.2e-31 107.2 2.2 6.2e-31 107.2 2.2 2.3 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EEQ35935.1 - 2.8e-18 65.5 7.5 4.8e-18 64.7 7.5 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EEQ35935.1 - 8.3e-10 38.5 3.3 1.1e-09 38.1 1.0 2.5 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 EEQ35935.1 - 0.078 12.7 1.4 0.14 11.9 1.4 1.4 1 0 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain Elf1 PF05129.13 EEQ35935.1 - 0.089 12.8 2.9 0.19 11.8 2.9 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like LINES_C PF14695.6 EEQ35935.1 - 0.49 9.9 1.6 0.67 9.4 0.2 2.0 2 0 0 2 2 2 0 Lines C-terminus Ribosomal_S20p PF01649.18 EEQ35935.1 - 2.6 8.8 11.8 1.2 9.8 4.2 2.6 2 1 0 2 2 2 0 Ribosomal protein S20 CSTF2_hinge PF14327.6 EEQ35936.1 - 2.3e-19 69.6 4.5 4.3e-19 68.8 4.5 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EEQ35936.1 - 2e-18 65.9 0.0 5.3e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RuvA_C PF07499.13 EEQ35936.1 - 0.043 14.3 0.2 0.23 11.9 0.1 2.3 3 0 0 3 3 3 0 RuvA, C-terminal domain TINF2_N PF14973.6 EEQ35936.1 - 0.055 13.8 1.9 0.076 13.4 1.1 1.6 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus RRM_occluded PF16842.5 EEQ35936.1 - 0.092 12.6 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif MR_MLE_C PF13378.6 EEQ35936.1 - 0.15 11.6 0.0 0.54 9.8 0.0 1.7 2 0 0 2 2 2 0 Enolase C-terminal domain-like CSTF2_hinge PF14327.6 EEQ35937.1 - 3.3e-20 72.3 2.2 3.3e-20 72.3 2.2 2.4 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EEQ35937.1 - 3.1e-10 39.7 0.0 2.7e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EEQ35937.1 - 1.1e-08 34.5 5.6 1.1e-08 34.5 5.6 3.1 3 0 0 3 3 3 2 Transcription termination and cleavage factor C-terminal PHM7_cyt PF14703.6 EEQ35937.1 - 0.19 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter zf-RING_2 PF13639.6 EEQ35938.1 - 2.6e-08 34.1 8.6 1.8e-06 28.2 4.6 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 EEQ35938.1 - 2.5e-07 30.8 5.8 4.3e-07 30.1 2.7 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ35938.1 - 3e-06 27.1 6.4 0.00035 20.5 2.0 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEQ35938.1 - 1e-05 25.3 9.6 3.7e-05 23.5 6.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ35938.1 - 1.7e-05 24.6 7.6 7.3e-05 22.6 4.6 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEQ35938.1 - 8.6e-05 22.5 1.4 0.0011 19.0 0.7 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EEQ35938.1 - 0.00015 21.5 4.2 0.0084 15.9 2.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ35938.1 - 0.0008 19.2 6.1 0.0054 16.6 3.4 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EEQ35938.1 - 0.0009 19.0 4.5 0.0012 18.6 2.5 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 EEQ35938.1 - 0.0035 17.3 4.9 0.076 13.0 2.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EEQ35938.1 - 0.004 17.0 1.2 1.1 9.2 0.5 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 EEQ35938.1 - 0.032 14.0 2.6 0.92 9.3 0.7 2.7 2 1 0 2 2 2 0 RING-like zinc finger YacG PF03884.14 EEQ35938.1 - 0.34 10.7 3.2 3.4 7.5 0.4 2.6 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG FANCL_C PF11793.8 EEQ35938.1 - 0.57 10.4 4.8 6.4 7.0 1.9 2.9 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EEQ35938.1 - 0.66 9.8 3.3 12 5.7 0.8 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EEQ35938.1 - 1.2 9.4 5.1 1.6 9.0 1.8 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Phage_Coat_A PF05357.13 EEQ35939.1 - 0.12 12.2 0.3 0.4 10.5 0.0 2.0 2 0 0 2 2 2 0 Phage Coat Protein A Fungal_trans PF04082.18 EEQ35940.1 - 7.8e-61 205.4 2.7 1.6e-60 204.4 2.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EEQ35940.1 - 1.1e-06 28.7 12.5 0.00047 20.5 2.9 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ35940.1 - 0.022 15.6 2.5 0.022 15.6 2.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Ribosomal_S8e PF01201.22 EEQ35941.1 - 4.1e-45 153.3 0.2 6.6e-45 152.6 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.12 EEQ35941.1 - 0.26 11.2 2.2 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 Homeo-prospero domain Sas10_Utp3 PF04000.15 EEQ35942.1 - 1.6e-11 44.7 0.9 1.6e-11 44.7 0.9 2.4 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Apt1 PF10351.9 EEQ35942.1 - 0.32 9.8 12.8 0.5 9.2 12.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain PUF PF00806.19 EEQ35943.1 - 5.1e-52 170.7 26.9 1.8e-08 33.6 0.2 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat PriX PF18689.1 EEQ35943.1 - 0.037 14.4 1.2 1.6 9.1 0.1 2.8 2 0 0 2 2 2 0 Primase X CPL PF08144.11 EEQ35943.1 - 0.043 14.2 0.3 29 5.0 0.0 3.6 2 1 1 3 3 3 0 CPL (NUC119) domain DUF5595 PF18077.1 EEQ35945.1 - 0.0084 16.2 0.9 0.023 14.8 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5595) Filament PF00038.21 EEQ35945.1 - 0.02 14.5 0.3 0.042 13.4 0.3 1.5 1 0 0 1 1 1 0 Intermediate filament protein HAP1_N PF04849.13 EEQ35945.1 - 0.058 12.6 1.7 0.098 11.8 1.7 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region FapA PF03961.13 EEQ35945.1 - 0.41 9.2 1.5 0.55 8.8 1.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DivIC PF04977.15 EEQ35945.1 - 1.9 8.3 4.5 0.36 10.6 0.1 2.0 2 0 0 2 2 2 0 Septum formation initiator Nucleoporin_FG PF13634.6 EEQ35946.1 - 1.7e-15 57.6 119.3 7e-06 26.8 34.2 4.2 1 1 2 3 3 3 3 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 EEQ35946.1 - 1.5e-07 30.4 29.7 1.8e-07 30.1 29.7 1.3 1 0 0 1 1 1 1 Nucleoporin FG repeated region DUF677 PF05055.12 EEQ35946.1 - 0.0029 16.5 0.0 0.0055 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF677) KIAA1430 PF13879.6 EEQ35946.1 - 0.58 11.0 0.1 0.58 11.0 0.1 2.6 3 0 0 3 3 3 0 KIAA1430 homologue SUIM_assoc PF16619.5 EEQ35946.1 - 1.5 8.9 10.9 1.4 9.0 8.1 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cor1 PF04803.12 EEQ35946.1 - 3.5 7.9 12.1 1.4 9.2 5.8 2.5 2 1 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF1664 PF07889.12 EEQ35946.1 - 5 7.2 7.0 7.4 6.6 0.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Bud13 PF09736.9 EEQ35947.1 - 3.8e-38 131.1 8.7 3.8e-38 131.1 8.7 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF4537 PF15057.6 EEQ35947.1 - 0.0066 16.5 0.1 0.017 15.2 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4537) PYC_OADA PF02436.18 EEQ35947.1 - 0.0087 15.8 1.2 0.015 15.0 1.2 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain TPK_catalytic PF04263.16 EEQ35947.1 - 0.022 14.8 3.6 0.35 10.9 3.6 2.5 1 1 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Troponin PF00992.20 EEQ35947.1 - 1.6 9.1 16.6 0.091 13.1 10.4 2.0 2 0 0 2 2 2 0 Troponin Mito_carr PF00153.27 EEQ35949.1 - 5.9e-73 240.9 2.0 2.3e-25 88.3 0.0 3.7 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_6 PF13405.6 EEQ35949.1 - 1.6e-06 27.5 1.7 3.1 8.0 0.0 6.2 6 0 0 6 6 6 2 EF-hand domain EF-hand_1 PF00036.32 EEQ35949.1 - 0.00012 21.4 1.2 0.35 10.5 0.0 4.6 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EEQ35949.1 - 0.06 13.2 0.0 11 5.9 0.0 3.9 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 EEQ35949.1 - 0.12 12.8 4.8 1.9 9.0 0.4 4.4 5 1 0 5 5 5 0 EF-hand domain pair XRN_M PF17846.1 EEQ35950.1 - 1.2e-88 298.1 6.1 1.2e-88 298.1 6.1 2.5 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EEQ35950.1 - 7.6e-81 271.1 0.2 1.4e-80 270.2 0.2 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EEQ35950.1 - 7e-55 185.8 0.2 7e-55 185.8 0.2 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain Xrn1_D3 PF18194.1 EEQ35950.1 - 3.4e-35 120.0 0.9 1e-34 118.4 0.9 1.9 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 XRN1_D2_D3 PF18334.1 EEQ35950.1 - 3.5e-28 97.6 0.0 3.7e-27 94.3 0.0 2.5 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EEQ35950.1 - 4.9e-17 61.8 0.2 1.2e-16 60.6 0.2 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain DUF5604 PF18300.1 EEQ35950.1 - 0.13 12.3 0.1 0.34 10.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5604) SOBP PF15279.6 EEQ35950.1 - 2.7 8.5 8.9 4.9 7.7 8.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein RapH_N PF18801.1 EEQ35951.1 - 0.013 15.5 0.0 0.041 14.0 0.0 1.8 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal DUF3461 PF11944.8 EEQ35951.1 - 0.092 12.9 0.5 1.8 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) zf-C2H2 PF00096.26 EEQ35953.1 - 1.9e-10 40.6 21.0 0.0011 19.3 1.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ35953.1 - 4.9e-10 39.4 18.1 1.6e-06 28.2 3.0 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ35953.1 - 3.9e-09 36.6 19.1 0.0055 17.4 2.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ35953.1 - 5.1e-07 29.8 9.7 0.0028 17.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ35953.1 - 0.00011 22.4 10.1 0.95 9.9 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ35953.1 - 0.00054 19.9 12.6 0.0012 18.8 0.7 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger GAGA PF09237.11 EEQ35953.1 - 0.0035 17.1 1.0 0.0035 17.1 1.0 2.7 2 2 0 2 2 1 1 GAGA factor Med13_C PF06333.12 EEQ35953.1 - 0.0076 15.6 13.6 0.0098 15.2 13.6 1.3 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain cEGF PF12662.7 EEQ35953.1 - 0.0091 15.9 1.0 3.8 7.5 0.0 2.4 2 0 0 2 2 2 2 Complement Clr-like EGF-like TFIIA PF03153.13 EEQ35953.1 - 0.028 14.4 14.0 0.028 14.4 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2HC_2 PF13913.6 EEQ35953.1 - 0.039 13.9 1.8 0.039 13.9 1.8 2.9 3 1 0 3 3 2 0 zinc-finger of a C2HC-type zf-Di19 PF05605.12 EEQ35953.1 - 0.1 12.9 13.4 0.26 11.6 6.2 2.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 EEQ35953.1 - 0.2 11.8 4.2 2.9 8.1 0.5 2.7 2 1 0 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 EEQ35953.1 - 0.41 11.0 15.3 1.2 9.6 1.8 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) SOG2 PF10428.9 EEQ35953.1 - 0.58 9.3 24.9 0.69 9.0 24.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein BolA PF01722.18 EEQ35953.1 - 0.65 10.3 6.1 0.28 11.5 1.0 2.3 1 1 1 2 2 2 0 BolA-like protein SPX PF03105.19 EEQ35953.1 - 1.1 9.1 21.3 1.2 9.0 21.3 1.2 1 0 0 1 1 1 0 SPX domain zf-C2HE PF16278.5 EEQ35953.1 - 1.1 9.8 12.1 10 6.6 0.9 3.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Ndc1_Nup PF09531.10 EEQ35953.1 - 1.1 7.8 15.6 1.3 7.6 15.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf_ZIC PF18366.1 EEQ35953.1 - 1.6 8.9 8.2 16 5.7 0.2 3.4 1 1 2 3 3 3 0 Zic proteins zinc finger domain Presenilin PF01080.17 EEQ35953.1 - 2.4 6.9 13.6 2.7 6.6 13.6 1.2 1 0 0 1 1 1 0 Presenilin Zn_ribbon_SprT PF17283.2 EEQ35953.1 - 2.4 8.1 8.1 29 4.7 4.3 2.5 2 0 0 2 2 2 0 SprT-like zinc ribbon domain LIM PF00412.22 EEQ35953.1 - 3.4 8.0 10.6 34 4.8 3.2 2.6 1 1 1 2 2 2 0 LIM domain Macoilin PF09726.9 EEQ35953.1 - 4 5.9 16.6 4.5 5.7 16.6 1.2 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 EEQ35953.1 - 4.9 5.7 26.0 5.5 5.5 26.0 1.0 1 0 0 1 1 1 0 Hamartin protein Apt1 PF10351.9 EEQ35953.1 - 5.3 5.8 16.5 5.8 5.6 16.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain C1_4 PF07975.12 EEQ35953.1 - 9 6.6 11.5 13 6.1 1.5 3.1 1 1 0 2 2 2 0 TFIIH C1-like domain ORC6 PF05460.13 EEQ35953.1 - 9.8 5.3 20.1 11 5.2 20.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Pkinase PF00069.25 EEQ35954.1 - 3.7e-45 154.3 0.5 3.9e-44 151.0 0.5 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35954.1 - 1.8e-17 63.5 0.0 4.9e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ35954.1 - 0.00069 19.0 0.1 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEQ35954.1 - 0.05 13.2 0.4 0.63 9.6 0.1 2.4 2 0 0 2 2 2 0 RIO1 family SUN PF03856.13 EEQ35955.1 - 1.8e-92 309.3 16.0 2.2e-92 309.0 16.0 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) zf-MYND PF01753.18 EEQ35955.1 - 0.12 12.5 1.8 0.3 11.2 1.8 1.6 1 0 0 1 1 1 0 MYND finger DUF1180 PF06679.12 EEQ35955.1 - 0.31 11.5 1.3 0.49 10.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CCDC24 PF15669.5 EEQ35955.1 - 1.3 8.8 3.3 2.1 8.2 3.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family APG12 PF04110.13 EEQ35956.1 - 4.8e-25 87.8 0.0 8.5e-25 87.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Kinetochor_Ybp2 PF08568.10 EEQ35957.1 - 1.7e-134 449.7 2.1 2.3e-134 449.3 2.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.10 EEQ35958.1 - 4.3e-09 36.2 0.1 4.3e-09 36.2 0.1 2.8 3 0 0 3 3 3 1 HPC2 and ubinuclein domain BCDHK_Adom3 PF10436.9 EEQ35959.1 - 5.9e-40 136.8 0.5 9.3e-40 136.1 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EEQ35959.1 - 1.1e-08 35.6 0.0 1e-07 32.5 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EEQ35959.1 - 4.7e-05 23.2 0.0 9.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase COX4 PF02936.14 EEQ35961.1 - 1.4e-07 31.6 0.3 1.4e-07 31.6 0.3 2.0 3 0 0 3 3 3 1 Cytochrome c oxidase subunit IV UQ_con PF00179.26 EEQ35962.1 - 3.4e-51 172.6 0.0 5.6e-51 171.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ35962.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEQ35962.1 - 0.023 15.0 0.0 0.044 14.1 0.0 1.7 1 1 0 1 1 1 0 RWD domain Peptidase_S8 PF00082.22 EEQ35963.1 - 1.5e-29 103.2 10.6 2.9e-29 102.3 10.6 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ35963.1 - 1.8e-11 44.5 0.1 4e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 UFD1 PF03152.14 EEQ35964.1 - 7.6e-23 80.8 0.1 1.8e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EEQ35964.1 - 2.7e-07 30.7 0.4 2.3e-06 27.7 0.0 2.6 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A zf_UBZ PF18439.1 EEQ35964.1 - 0.31 10.7 10.2 6.3 6.5 0.1 4.3 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger PRP21_like_P PF12230.8 EEQ35964.1 - 0.67 9.8 4.3 3 7.7 1.1 2.3 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-BED PF02892.15 EEQ35964.1 - 3.6 7.7 10.1 24 5.1 3.4 3.7 2 1 1 3 3 3 0 BED zinc finger Peptidase_M16_C PF05193.21 EEQ35965.1 - 5e-19 69.0 0.2 7.2e-14 52.2 0.0 3.3 3 1 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEQ35965.1 - 3.8e-09 36.7 2.7 7.3e-08 32.5 0.0 3.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Ribosomal_S10 PF00338.22 EEQ35965.1 - 0.088 13.0 0.6 0.46 10.7 0.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S10p/S20e RNase_J_C PF17770.1 EEQ35965.1 - 0.15 13.1 1.4 0.45 11.6 0.1 2.6 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Pkinase PF00069.25 EEQ35966.1 - 3.3e-52 177.4 0.0 4.8e-52 176.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ35966.1 - 1e-22 80.7 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ35966.1 - 0.002 17.5 0.0 0.81 8.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 EEQ35966.1 - 0.039 13.6 0.0 11 5.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EEQ35966.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EEQ35966.1 - 0.15 11.9 0.0 0.45 10.4 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEQ35966.1 - 0.36 9.6 4.1 0.26 10.0 0.1 2.5 3 0 0 3 3 3 0 Fungal protein kinase Actin PF00022.19 EEQ35967.1 - 8.9e-101 337.4 0.0 5.4e-100 334.9 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEQ35967.1 - 0.0063 15.4 0.0 0.028 13.3 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein Actin_micro PF17003.5 EEQ35967.1 - 0.1 11.7 0.9 0.9 8.6 0.2 2.1 2 0 0 2 2 2 0 Putative actin-like family GCD14 PF08704.10 EEQ35968.1 - 3.7e-77 259.3 0.0 4.8e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EEQ35968.1 - 0.0039 17.0 0.0 0.0062 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EEQ35968.1 - 0.013 15.3 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GCD14_N PF14801.6 EEQ35968.1 - 0.044 13.6 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term LSM PF01423.22 EEQ35969.1 - 7.4e-15 54.4 0.0 1.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EEQ35969.1 - 0.15 11.7 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Hfq protein RPN7 PF10602.9 EEQ35970.1 - 2.5e-53 180.3 2.0 4.9e-53 179.4 2.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EEQ35970.1 - 5.7e-14 52.5 1.3 1.6e-13 51.0 0.4 2.1 2 0 0 2 2 2 1 PCI domain UQ_con PF00179.26 EEQ35971.1 - 7.1e-39 132.7 0.1 9e-39 132.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Aldedh PF00171.22 EEQ35972.1 - 3.2e-161 536.9 0.0 3.7e-161 536.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EEQ35972.1 - 0.0034 16.9 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF4355 PF14265.6 EEQ35973.1 - 1.2 9.3 15.4 4.6 7.5 12.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) DUF1682 PF07946.14 EEQ35973.1 - 2.7 7.1 14.8 3.9 6.6 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Ank_2 PF12796.7 EEQ35974.1 - 1.6e-14 54.3 1.5 1.7e-05 25.3 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ35974.1 - 3.5e-13 49.8 1.0 3e-05 24.5 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EEQ35974.1 - 1.2e-12 47.7 3.1 0.0002 21.7 0.4 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EEQ35974.1 - 1.3e-10 40.6 1.4 0.039 14.5 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EEQ35974.1 - 6.3e-09 35.9 1.8 0.0085 16.4 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EEQ35974.1 - 1.7e-06 27.8 0.0 1.5e-05 24.8 0.0 2.6 1 1 0 1 1 1 1 KilA-N domain TFIIA PF03153.13 EEQ35974.1 - 0.0055 16.7 26.0 0.0055 16.7 26.0 2.7 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF3231 PF11553.8 EEQ35974.1 - 0.045 13.4 1.1 0.12 12.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3231) DUF2973 PF11189.8 EEQ35974.1 - 7.4 6.7 5.7 3.6 7.7 0.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Aminotran_3 PF00202.21 EEQ35975.1 - 2.2e-58 197.9 0.0 2.5e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EEQ35975.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.16 EEQ35976.1 - 1.2e-35 123.1 18.6 1.2e-35 123.1 18.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ35976.1 - 4.2e-11 42.4 9.2 4.2e-11 42.4 9.2 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter MRP_L53 PF10780.9 EEQ35976.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 PfkB PF00294.24 EEQ35977.1 - 5.3e-07 29.2 0.0 6.3e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EEQ35977.1 - 9.4e-05 21.9 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase GRASP55_65 PF04495.14 EEQ35978.1 - 1.9e-39 135.1 0.0 7.1e-37 126.8 0.0 2.2 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PRTase_1 PF11202.8 EEQ35978.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase (PRTase) DAO PF01266.24 EEQ35979.1 - 2.4e-06 27.4 0.0 2.4e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ35979.1 - 0.00044 19.6 0.0 0.00044 19.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ35979.1 - 0.0078 16.4 0.1 0.018 15.2 0.1 1.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ35979.1 - 0.099 13.2 0.2 0.19 12.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEQ35979.1 - 0.16 11.0 0.2 0.21 10.6 0.2 1.1 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EEQ35979.1 - 0.24 10.7 0.2 0.33 10.2 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ribophorin_II PF05817.14 EEQ35980.1 - 2.2e-19 69.5 0.2 2.5e-19 69.3 0.2 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_S24 PF00717.23 EEQ35981.1 - 5.4e-08 32.7 0.0 2.5e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 EEQ35981.1 - 0.0019 18.0 0.0 0.0067 16.2 0.0 1.9 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 FAD_binding_6 PF00970.24 EEQ35982.1 - 2.3e-05 24.6 0.0 8.1e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EEQ35982.1 - 0.033 14.8 0.0 1.4 9.6 0.0 2.7 1 1 1 2 2 2 0 Oxidoreductase NAD-binding domain DUF1548 PF07579.11 EEQ35983.1 - 2.1 8.7 6.5 1.2 9.5 0.1 3.6 3 2 1 4 4 4 0 Domain of Unknown Function (DUF1548) CBFD_NFYB_HMF PF00808.23 EEQ35984.1 - 8.9e-10 38.7 0.1 2.3e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ35984.1 - 7.1e-06 26.4 0.0 1.3e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF4358 PF14270.6 EEQ35984.1 - 0.061 13.6 0.4 0.15 12.4 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4358) MRP-L27 PF09809.9 EEQ35985.1 - 1.2e-28 99.2 0.1 2.3e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Cu-oxidase_3 PF07732.15 EEQ35986.1 - 1.2e-36 125.3 2.3 7.7e-36 122.7 0.4 2.6 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EEQ35986.1 - 2.2e-33 114.9 3.7 1e-24 86.9 0.5 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EEQ35986.1 - 9.7e-12 45.3 0.0 4.5e-11 43.1 0.0 2.1 1 1 0 1 1 1 1 Multicopper oxidase Ilm1 PF10311.9 EEQ35987.1 - 7.8e-16 58.2 9.8 3.2e-10 39.9 4.7 2.1 1 1 1 2 2 2 2 Increased loss of mitochondrial DNA protein 1 TMEM43 PF07787.12 EEQ35987.1 - 3.3 7.0 5.4 0.95 8.8 2.2 1.6 1 1 1 2 2 2 0 Transmembrane protein 43 Med17 PF10156.9 EEQ35988.1 - 3.5e-112 375.5 8.7 5e-112 375.0 8.7 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Ras PF00071.22 EEQ35989.1 - 2.8e-65 218.9 0.5 3.3e-65 218.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ35989.1 - 1.3e-36 125.4 0.2 2e-36 124.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ35989.1 - 1.2e-17 63.9 0.1 1.5e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ35989.1 - 8.1e-07 28.6 0.1 9.2e-07 28.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EEQ35989.1 - 1.2e-06 28.6 0.4 0.031 14.2 0.1 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEQ35989.1 - 6.8e-05 22.9 0.0 9.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ35989.1 - 0.00014 21.5 0.2 0.00038 20.1 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEQ35989.1 - 0.0014 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 EEQ35989.1 - 0.0027 18.2 0.0 0.043 14.2 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ35989.1 - 0.0054 17.1 0.0 0.0081 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ35989.1 - 0.015 15.5 0.0 0.039 14.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EEQ35989.1 - 0.02 14.6 0.1 0.3 10.8 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EEQ35989.1 - 0.035 14.6 0.0 0.052 14.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 EEQ35989.1 - 0.035 13.6 0.0 0.23 11.0 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EEQ35989.1 - 0.039 13.5 0.3 0.077 12.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 EEQ35989.1 - 0.047 13.5 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EEQ35989.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Septin CENP-M PF11111.8 EEQ35989.1 - 0.056 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_5 PF07728.14 EEQ35989.1 - 0.069 13.2 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EEQ35989.1 - 0.084 12.3 0.0 0.21 11.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein TRAM_LAG1_CLN8 PF03798.16 EEQ35990.1 - 2.6e-35 122.0 18.4 2.6e-35 122.0 18.4 1.4 2 0 0 2 2 2 1 TLC domain PfkB PF00294.24 EEQ35991.1 - 9e-41 140.1 0.1 1.1e-40 139.9 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DNA_pol_phi PF04931.13 EEQ35993.1 - 1e-184 615.8 46.1 1.3e-184 615.4 46.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi BEX PF04538.12 EEQ35993.1 - 0.058 14.0 0.4 0.058 14.0 0.4 2.7 2 0 0 2 2 2 0 Brain expressed X-linked like family Trypan_PARP PF05887.11 EEQ35993.1 - 5.2 7.1 7.6 11 6.1 7.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ABC_membrane PF00664.23 EEQ35994.1 - 3e-46 158.3 6.5 4.6e-46 157.7 6.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ35994.1 - 1.7e-29 103.1 0.7 5.5e-29 101.4 0.0 2.3 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.19 EEQ35994.1 - 8.6e-07 28.6 0.0 1.5e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EEQ35994.1 - 0.00013 22.4 0.9 0.0011 19.4 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 EEQ35994.1 - 0.0013 19.2 0.3 0.034 14.6 0.3 2.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EEQ35994.1 - 0.0051 15.7 0.2 0.0051 15.7 0.2 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class PDDEXK_1 PF12705.7 EEQ35994.1 - 0.0096 15.9 0.3 0.032 14.2 0.0 1.9 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_25 PF13481.6 EEQ35994.1 - 0.019 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EEQ35994.1 - 0.036 14.4 2.3 0.15 12.3 0.1 2.9 3 1 0 3 3 3 0 AAA domain Gasdermin_C PF17708.1 EEQ35994.1 - 0.051 13.7 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Gasdermin PUB domain DUF2073 PF09846.9 EEQ35994.1 - 0.14 12.1 2.3 0.2 11.5 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2073) Peptidase_M49 PF03571.15 EEQ35995.1 - 1.3e-229 763.2 0.0 1.8e-229 762.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 MogR_DNAbind PF12181.8 EEQ35995.1 - 0.057 13.3 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 DNA binding domain of the motility gene repressor (MogR) DUF4120 PF13496.6 EEQ35995.1 - 0.084 13.2 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) BCNT PF07572.12 EEQ35996.1 - 5.3e-24 84.1 2.4 1e-23 83.2 2.4 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development KH_1 PF00013.29 EEQ35997.1 - 2.3e-39 133.0 2.1 7.9e-13 48.0 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EEQ35997.1 - 2.8e-11 43.1 0.3 0.00085 19.1 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EEQ35997.1 - 1.3e-06 28.2 0.1 0.06 13.2 0.1 3.7 3 1 0 3 3 3 2 KH domain KH_5 PF13184.6 EEQ35997.1 - 0.00017 21.6 3.2 2.1 8.5 0.3 3.4 3 0 0 3 3 3 3 NusA-like KH domain OPT PF03169.15 EEQ35998.1 - 6.5e-144 480.9 24.3 7.5e-144 480.7 24.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Jagunal PF07086.12 EEQ35998.1 - 0.083 13.0 1.4 0.14 12.2 0.2 2.1 2 0 0 2 2 2 0 Jagunal, ER re-organisation during oogenesis CBS PF00571.28 EEQ35999.1 - 5.3e-24 84.4 6.3 2.7e-10 40.6 0.2 4.4 4 0 0 4 4 4 4 CBS domain Zip PF02535.22 EEQ36000.1 - 5e-75 252.8 5.3 5.6e-75 252.6 5.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter HPIP PF15226.6 EEQ36001.1 - 0.27 11.6 3.7 0.33 11.4 0.5 2.7 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family WD40_alt PF14077.6 EEQ36001.1 - 1.2 9.0 4.0 1.1 9.2 0.2 2.8 3 0 0 3 3 3 0 Alternative WD40 repeat motif Cas6 PF09559.10 EEQ36001.1 - 2.6 7.9 6.9 5.2 7.0 6.9 1.4 1 0 0 1 1 1 0 Cas6 Crispr APC_N_CC PF16689.5 EEQ36001.1 - 2.8 8.1 7.9 20 5.3 2.1 3.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Cu_amine_oxidN1 PF07833.11 EEQ36001.1 - 3.2 8.3 8.4 61 4.2 5.2 3.5 1 1 1 2 2 2 0 Copper amine oxidase N-terminal domain Ribosomal_S8 PF00410.19 EEQ36002.1 - 5.6e-15 55.4 0.0 5.2e-14 52.3 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 Coat_X PF07552.11 EEQ36002.1 - 0.044 13.6 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Spore Coat Protein X and V domain COX16 PF14138.6 EEQ36003.1 - 0.052 14.0 0.1 0.12 12.9 0.1 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 PNK3P PF08645.11 EEQ36004.1 - 1.5e-48 164.6 0.1 1.9e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase DUF2326 PF10088.9 EEQ36004.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2326) zf-C2H2_jaz PF12171.8 EEQ36005.1 - 0.00048 20.3 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ36005.1 - 0.0046 17.3 0.0 0.0094 16.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EEQ36005.1 - 0.0067 16.8 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type SNRNP27 PF08648.12 EEQ36005.1 - 0.014 15.4 0.2 0.057 13.5 0.2 2.1 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins zf-C2H2_9 PF16293.5 EEQ36005.1 - 0.025 14.4 0.2 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_4 PF13894.6 EEQ36005.1 - 0.052 14.4 0.0 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EEQ36005.1 - 0.1 13.0 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 EEQ36005.1 - 0.18 12.1 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF612 PF04747.12 EEQ36005.1 - 1.1 8.3 13.3 0.07 12.2 7.7 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF612 Pro_isomerase PF00160.21 EEQ36007.1 - 7.6e-48 162.8 0.1 9.2e-48 162.5 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD rve PF00665.26 EEQ36008.1 - 2.6e-22 79.2 0.0 6.3e-22 78.0 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EEQ36008.1 - 8.1e-05 22.4 0.1 0.00038 20.2 0.1 2.3 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 EEQ36008.1 - 0.0013 18.4 0.0 0.0048 16.6 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain CGGC PF08821.11 EEQ36008.1 - 0.12 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 CGGC domain F-box_5 PF18511.1 EEQ36008.1 - 0.17 11.5 2.9 8.7 6.0 0.2 2.5 2 0 0 2 2 2 0 F-box RVT_2 PF07727.14 EEQ36009.1 - 8e-84 281.1 0.1 9.5e-84 280.8 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EEQ36009.1 - 0.0066 16.0 0.0 0.012 15.2 0.0 1.4 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ENTH PF01417.20 EEQ36011.1 - 3.5e-44 149.8 0.1 5.1e-44 149.3 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EEQ36011.1 - 0.00037 19.6 0.0 0.00053 19.1 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF5102 PF17104.5 EEQ36011.1 - 0.009 16.1 3.8 0.009 16.1 3.8 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF5102) SAC3_GANP PF03399.16 EEQ36012.1 - 5.2e-107 357.6 0.2 8.3e-107 356.9 0.2 1.3 1 0 0 1 1 1 1 SAC3/GANP family SAC3 PF12209.8 EEQ36012.1 - 7.6e-21 74.1 1.3 3.2e-20 72.1 1.3 2.2 1 0 0 1 1 1 1 Leucine permease transcriptional regulator helical domain CSN8_PSD8_EIF3K PF10075.9 EEQ36012.1 - 0.12 12.4 0.9 0.24 11.4 0.0 2.0 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family SlyX PF04102.12 EEQ36012.1 - 2.9 8.6 4.9 6.8 7.4 0.2 3.4 2 1 0 2 2 2 0 SlyX Methyltransf_16 PF10294.9 EEQ36013.1 - 1.2e-12 47.9 0.1 1.2e-09 38.1 0.1 2.1 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EEQ36013.1 - 9.3e-05 22.3 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Semialdhyde_dhC PF02774.18 EEQ36014.1 - 7.7e-41 140.2 0.0 1.8e-40 139.0 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EEQ36014.1 - 6.5e-32 110.5 0.0 1.2e-31 109.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 EEQ36014.1 - 0.00055 20.6 0.0 0.0019 18.9 0.0 2.0 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Sacchrp_dh_NADP PF03435.18 EEQ36014.1 - 0.0024 18.1 0.0 0.0071 16.6 0.0 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EEQ36014.1 - 0.078 12.9 0.0 0.27 11.1 0.0 1.9 1 1 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 EEQ36014.1 - 0.099 12.8 0.0 0.29 11.3 0.0 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SSrecog PF03531.14 EEQ36015.1 - 2.7e-30 104.1 3.0 3.7e-28 97.2 0.1 3.6 4 0 0 4 4 4 2 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 EEQ36015.1 - 5.3e-29 100.5 0.1 5.7e-27 94.0 0.0 3.2 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 EEQ36015.1 - 2.4e-28 98.4 0.0 2.1e-26 92.1 0.0 3.3 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Mem_trans PF03547.18 EEQ36016.1 - 7.2e-34 116.8 0.0 2.5e-33 115.0 0.0 1.7 1 1 0 1 1 1 1 Membrane transport protein FAM176 PF14851.6 EEQ36016.1 - 0.13 11.9 0.8 0.34 10.6 0.8 1.7 1 0 0 1 1 1 0 FAM176 family Apt1 PF10351.9 EEQ36016.1 - 4.8 5.9 13.2 6.7 5.4 13.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Bap31 PF05529.12 EEQ36017.1 - 1.9e-47 160.5 1.4 2.6e-47 160.0 1.4 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EEQ36017.1 - 1.6e-05 24.8 4.7 3.3e-05 23.8 4.7 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EEQ36017.1 - 0.054 13.3 3.2 2.1 8.2 2.3 2.7 3 0 0 3 3 3 0 Septum formation initiator PHR PF08005.12 EEQ36017.1 - 0.059 14.0 0.1 0.13 13.0 0.1 1.5 1 1 0 1 1 1 0 PHR domain Dus PF01207.17 EEQ36018.1 - 3.1e-45 154.6 0.0 5.7e-44 150.4 0.0 2.2 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Utp21 PF04192.12 EEQ36019.1 - 1.8e-79 266.6 0.4 2.8e-79 265.9 0.4 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EEQ36019.1 - 6.4e-15 55.2 0.0 0.00028 21.1 0.0 5.7 3 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ36019.1 - 6.8e-10 39.4 16.9 2.6e-09 37.5 0.1 6.8 11 0 0 11 11 11 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EEQ36019.1 - 0.0024 16.5 0.0 0.0047 15.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 EEQ36019.1 - 0.0088 15.9 0.0 0.075 12.9 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Bacteriocin_IIc PF10439.9 EEQ36019.1 - 0.051 13.7 0.0 0.051 13.7 0.0 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Vps39_1 PF10366.9 EEQ36020.1 - 7e-28 97.1 5.7 9e-28 96.7 0.1 3.5 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 EEQ36020.1 - 1.3e-20 73.9 0.1 5.6e-20 71.8 0.1 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 SUKH-3 PF14433.6 EEQ36020.1 - 0.18 12.3 0.0 0.45 11.0 0.0 1.6 1 0 0 1 1 1 0 SUKH-3 immunity protein Rxt3 PF08642.10 EEQ36021.1 - 2.4e-21 76.8 0.0 2.4e-21 76.8 0.0 4.0 2 2 0 2 2 1 1 Histone deacetylation protein Rxt3 DUF4778 PF16008.5 EEQ36021.1 - 0.032 14.3 8.0 0.046 13.8 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) FAM76 PF16046.5 EEQ36021.1 - 0.082 12.3 14.0 0.12 11.7 14.0 1.3 1 0 0 1 1 1 0 FAM76 protein Presenilin PF01080.17 EEQ36021.1 - 0.39 9.4 12.4 0.51 9.0 12.4 1.3 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 EEQ36021.1 - 0.8 6.8 13.7 0.97 6.5 13.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 EEQ36021.1 - 1.3 7.5 19.2 1.9 7.0 19.2 1.2 1 0 0 1 1 1 0 Macoilin family Sec62 PF03839.16 EEQ36021.1 - 3.1 7.3 6.0 6.2 6.3 6.0 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.16 EEQ36021.1 - 3.6 7.6 7.4 6.2 6.8 7.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1387 PF07139.11 EEQ36021.1 - 5 6.8 17.9 7.7 6.1 17.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Spem1 PF15670.5 EEQ36021.1 - 5.3 6.6 19.7 6.2 6.3 18.8 1.5 1 1 0 1 1 1 0 Spermatid maturation protein 1 Endostatin PF06482.11 EEQ36021.1 - 5.9 6.3 14.5 9 5.7 14.5 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin PAT1 PF09770.9 EEQ36021.1 - 7.4 4.7 18.0 9.1 4.4 18.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4050 PF13259.6 EEQ36022.1 - 1.3e-15 58.2 5.2 9.5e-11 42.3 0.2 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF4050) GBP_C PF02841.14 EEQ36023.1 - 0.014 14.9 1.3 0.019 14.4 0.8 1.5 1 1 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Ribosomal_L31e PF01198.19 EEQ36025.1 - 4.7e-15 55.6 0.3 5.9e-15 55.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Fn3_assoc PF13287.6 EEQ36025.1 - 0.068 13.3 0.0 4.7 7.4 0.0 2.1 1 1 1 2 2 2 0 Fn3 associated AAA PF00004.29 EEQ36026.1 - 1.3e-54 184.1 0.0 4.1e-43 147.0 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ36026.1 - 3.4e-13 49.2 0.4 2.6e-05 23.9 0.1 3.3 3 1 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 EEQ36026.1 - 9e-07 29.4 0.5 0.023 15.1 0.0 4.5 4 1 1 5 5 5 1 AAA ATPase domain RuvB_N PF05496.12 EEQ36026.1 - 8.2e-06 25.7 0.0 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEQ36026.1 - 0.00011 22.4 0.0 0.46 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EEQ36026.1 - 0.00028 20.1 0.0 0.00051 19.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TsaE PF02367.17 EEQ36026.1 - 0.00047 20.1 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_2 PF07724.14 EEQ36026.1 - 0.00064 19.9 0.0 0.0079 16.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EEQ36026.1 - 0.00065 20.1 0.0 0.019 15.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 EEQ36026.1 - 0.0013 18.6 0.9 3.3 7.6 0.0 3.5 3 0 0 3 3 3 1 NACHT domain IstB_IS21 PF01695.17 EEQ36026.1 - 0.0021 17.8 0.0 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 EEQ36026.1 - 0.0032 17.7 0.7 0.049 13.9 0.0 3.0 2 2 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEQ36026.1 - 0.0043 16.6 0.0 0.037 13.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 EEQ36026.1 - 0.0067 16.4 0.1 0.066 13.2 0.0 2.8 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EEQ36026.1 - 0.0079 16.5 0.0 0.2 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ36026.1 - 0.0095 16.5 0.0 0.15 12.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EEQ36026.1 - 0.014 15.5 0.0 0.74 9.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EEQ36026.1 - 0.014 15.4 0.1 0.063 13.3 0.0 2.2 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 EEQ36026.1 - 0.014 14.6 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase PF06745.13 EEQ36026.1 - 0.015 14.7 0.0 0.035 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 EEQ36026.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.16 EEQ36026.1 - 0.029 13.8 0.0 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 EEQ36026.1 - 0.035 14.0 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EEQ36026.1 - 0.053 12.7 0.0 4.2 6.5 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain SKI PF01202.22 EEQ36026.1 - 0.064 13.4 0.0 4.3 7.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_25 PF13481.6 EEQ36026.1 - 0.065 12.8 0.7 0.71 9.4 0.1 2.6 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 EEQ36026.1 - 0.091 12.5 0.1 0.61 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.31 EEQ36027.1 - 1.6e-06 28.1 0.1 3.3e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EEQ36027.1 - 8.8e-06 25.7 0.3 1.3e-05 25.2 0.3 1.5 1 1 0 1 1 1 1 Pam16 CDP-OH_P_tran_2 PF08009.11 EEQ36027.1 - 0.066 13.1 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 PK PF00224.21 EEQ36028.1 - 2.3e-86 289.8 0.7 3.2e-86 289.4 0.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EEQ36028.1 - 6.4e-38 129.6 0.8 1.3e-37 128.6 0.2 1.9 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EEQ36028.1 - 0.00081 18.6 0.2 0.0031 16.7 0.1 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Ubie_methyltran PF01209.18 EEQ36030.1 - 7.8e-84 280.6 0.1 9.1e-84 280.4 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EEQ36030.1 - 2.4e-12 47.4 0.0 7e-12 45.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ36030.1 - 1.5e-10 41.6 0.0 2.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ36030.1 - 8.7e-09 36.0 0.0 1.5e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ36030.1 - 1e-07 31.8 0.0 5.8e-07 29.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EEQ36030.1 - 0.068 13.0 0.0 0.93 9.3 0.0 2.2 2 0 0 2 2 2 0 Hypothetical methyltransferase Med1 PF10744.9 EEQ36031.1 - 3.7e-27 95.4 0.4 8e-27 94.3 0.3 1.4 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 IF2_N PF04760.15 EEQ36031.1 - 0.13 12.1 0.4 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region IF-2B PF01008.17 EEQ36032.1 - 1.5e-66 224.5 0.2 4.4e-66 223.0 0.2 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family ABC_sub_bind PF04392.12 EEQ36032.1 - 0.0024 17.2 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter substrate binding protein SPATA1_C PF15743.5 EEQ36032.1 - 0.19 11.8 1.6 0.33 11.0 1.6 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus ACOX PF01756.19 EEQ36033.1 - 2e-40 138.2 0.0 3.9e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EEQ36033.1 - 4.8e-23 81.2 0.0 9.6e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EEQ36033.1 - 4e-12 46.8 0.0 1.1e-11 45.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EEQ36033.1 - 7e-05 23.1 0.0 0.002 18.4 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HSP20 PF00011.21 EEQ36034.1 - 2.3e-05 24.5 4.5 3.4e-05 23.9 4.5 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Pih1_fungal_CS PF18482.1 EEQ36034.1 - 0.057 13.9 1.3 0.064 13.8 0.1 1.8 2 0 0 2 2 2 0 Fungal Pih1 CS domain CS PF04969.16 EEQ36034.1 - 0.09 13.8 0.3 0.09 13.8 0.3 1.7 2 0 0 2 2 2 0 CS domain LRR_4 PF12799.7 EEQ36035.1 - 9.1e-32 108.6 44.3 1.5e-07 31.6 4.0 7.2 1 1 6 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEQ36035.1 - 1.9e-21 75.6 33.5 1.1e-05 25.1 0.5 6.0 5 1 0 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 EEQ36035.1 - 8.6e-17 61.2 18.4 4.4e-08 32.8 1.9 4.5 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EEQ36035.1 - 0.0012 18.7 24.8 0.58 10.4 0.3 7.6 8 1 1 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 EEQ36035.1 - 0.39 11.4 31.4 22 6.1 0.4 9.4 10 1 0 10 10 10 0 Leucine Rich Repeat UB2H PF14814.6 EEQ36035.1 - 0.45 10.6 4.9 60 3.8 0.1 4.6 2 2 4 6 6 6 0 Bifunctional transglycosylase second domain PP-binding PF00550.25 EEQ36036.1 - 3.1e-11 43.5 0.9 5.4e-11 42.7 0.8 1.5 1 1 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EEQ36036.1 - 2e-05 24.7 0.8 4.3e-05 23.7 0.7 1.6 1 1 0 1 1 1 1 Acyl-carrier DHR-2 PF06920.13 EEQ36037.1 - 3.5e-47 161.3 2.6 8.8e-47 159.9 2.6 1.6 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 EEQ36037.1 - 3.1e-13 49.4 0.0 2e-12 46.7 0.0 2.2 1 1 0 1 1 1 1 DOCK N-terminus AA_permease PF00324.21 EEQ36039.1 - 7.8e-53 179.7 31.2 1.4e-51 175.6 31.2 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ36039.1 - 4.9e-16 58.6 27.0 6.4e-16 58.2 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease HSP20 PF00011.21 EEQ36040.1 - 3.1e-05 24.1 9.1 0.033 14.3 0.5 4.2 4 1 0 4 4 4 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EEQ36040.1 - 0.066 12.8 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 HSP20-like domain found in ArsA SLC12 PF03522.15 EEQ36040.1 - 1.1 8.2 18.8 0.028 13.4 11.8 1.9 2 0 0 2 2 2 0 Solute carrier family 12 MCM3AP_GANP PF16769.5 EEQ36040.1 - 3.5 5.7 12.4 5.3 5.2 12.4 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP PLA2_B PF01735.18 EEQ36041.1 - 3.5e-185 616.1 2.6 4.7e-185 615.7 2.6 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DUF3172 PF11371.8 EEQ36041.1 - 0.074 12.7 0.1 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3172) IBR PF01485.21 EEQ36041.1 - 0.16 12.2 2.3 0.31 11.3 1.4 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain WD40 PF00400.32 EEQ36042.1 - 2.2e-49 164.4 29.3 2.5e-07 31.3 0.9 11.7 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36042.1 - 2.4e-17 63.0 11.0 0.0001 22.5 0.0 9.7 3 3 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EEQ36042.1 - 3.9e-17 62.5 0.7 7.2e-17 61.6 0.7 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 EEQ36042.1 - 2.7e-10 40.1 4.4 0.00058 19.3 0.2 5.7 4 3 0 5 5 5 2 WD40-like domain Nup160 PF11715.8 EEQ36042.1 - 6.9e-10 38.2 7.6 0.076 11.6 0.0 5.4 3 2 1 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ36042.1 - 4.1e-05 22.7 6.0 0.68 8.8 0.2 5.6 5 1 2 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EEQ36042.1 - 0.0014 17.5 10.6 0.077 11.7 0.0 5.3 3 2 1 5 5 5 1 Nup133 N terminal like Hira PF07569.11 EEQ36042.1 - 0.0092 15.7 1.9 2.2 7.9 0.0 4.2 4 0 0 4 4 4 1 TUP1-like enhancer of split PALB2_WD40 PF16756.5 EEQ36042.1 - 0.012 14.5 9.4 5.4 5.8 0.2 5.0 4 2 1 5 5 5 0 Partner and localizer of BRCA2 WD40 domain ELYS-bb PF16687.5 EEQ36042.1 - 0.053 12.1 0.1 0.75 8.3 0.0 2.6 2 1 0 2 2 2 0 beta-propeller of ELYS nucleoporin Med15_fungi PF05397.12 EEQ36043.1 - 2.7e-37 127.4 5.5 2.7e-37 127.4 5.5 4.5 4 1 0 4 4 4 1 Mediator complex subunit 15 Gal11_ABD1 PF18535.1 EEQ36043.1 - 9e-24 83.4 10.9 9e-24 83.4 10.9 7.3 6 3 1 7 7 7 1 Gal11 activator-binding domain (ABD1) KIX_2 PF16987.5 EEQ36043.1 - 2.1e-18 66.1 7.6 7.2e-18 64.4 0.8 4.6 3 0 0 3 3 3 1 KIX domain TFIIS_M PF07500.14 EEQ36043.1 - 0.00083 19.8 1.2 0.0036 17.8 0.5 2.5 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain LMWPc PF01451.21 EEQ36044.1 - 1.6e-34 119.3 0.0 1.8e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Not3 PF04065.15 EEQ36045.1 - 2e-72 243.4 22.0 2e-72 243.4 22.0 1.6 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EEQ36045.1 - 3.9e-36 124.0 4.4 4.3e-36 123.9 2.7 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family ATG11 PF10377.9 EEQ36045.1 - 0.21 11.6 0.1 0.21 11.6 0.1 2.6 2 1 0 2 2 2 0 Autophagy-related protein 11 Baculo_PEP_C PF04513.12 EEQ36045.1 - 2.3 8.3 5.0 8.7 6.4 0.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YebO PF13974.6 EEQ36045.1 - 3.7 7.7 6.7 0.24 11.5 0.2 2.4 2 0 0 2 2 2 0 YebO-like protein LMBR1 PF04791.16 EEQ36045.1 - 3.8 6.3 5.5 7.4 5.3 5.5 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein YabA PF06156.13 EEQ36045.1 - 6.5 7.4 18.8 0.08 13.6 3.7 3.7 1 1 2 3 3 3 0 Initiation control protein YabA Syntaxin_2 PF14523.6 EEQ36045.1 - 6.8 7.1 17.4 0.15 12.5 6.3 2.9 1 1 2 3 3 3 0 Syntaxin-like protein Prominin PF05478.11 EEQ36045.1 - 6.9 4.5 9.4 0.67 7.8 3.3 1.9 1 1 0 2 2 2 0 Prominin Opy2 PF09463.10 EEQ36046.1 - 1e-07 32.1 13.1 1.6e-07 31.5 13.1 1.3 1 0 0 1 1 1 1 Opy2 protein Transketolase_N PF00456.21 EEQ36047.1 - 9.4e-159 527.8 0.0 1.3e-158 527.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EEQ36047.1 - 6e-47 159.6 0.0 1.2e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EEQ36047.1 - 5.5e-12 45.7 0.0 1.2e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EEQ36047.1 - 4.5e-05 22.8 0.0 0.00013 21.3 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase ADH_N PF08240.12 EEQ36048.1 - 9.5e-30 102.7 0.1 2e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ36048.1 - 7.2e-28 97.2 1.3 1.1e-27 96.5 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ36048.1 - 9e-06 26.8 0.0 1.5e-05 26.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EEQ36048.1 - 0.014 15.1 0.7 0.02 14.6 0.7 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Sugar_tr PF00083.24 EEQ36049.1 - 2.9e-80 270.3 16.9 3.4e-80 270.1 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36049.1 - 2.6e-24 85.8 25.1 3.1e-24 85.5 24.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ36049.1 - 2.4e-05 23.4 8.6 2.4e-05 23.4 8.6 1.8 2 0 0 2 2 2 1 MFS_1 like family DUF2937 PF11157.8 EEQ36049.1 - 0.018 14.8 0.1 0.057 13.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) PhaG_MnhG_YufB PF03334.14 EEQ36049.1 - 6.4 7.1 12.5 0.28 11.4 2.6 2.5 2 0 0 2 2 2 0 Na+/H+ antiporter subunit Vitelline_membr PF10542.9 EEQ36050.1 - 0.026 14.4 1.5 0.084 12.7 1.5 1.8 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region Gal_mutarotas_2 PF13802.6 EEQ36051.1 - 1.5e-15 57.2 0.1 3.2e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_31 PF01055.26 EEQ36051.1 - 1.8e-15 57.1 0.0 2.5e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Cupin_1 PF00190.22 EEQ36051.1 - 0.067 12.8 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Cupin Glyco_hydro_31 PF01055.26 EEQ36052.1 - 1.3e-78 265.2 0.0 1.5e-78 265.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 FA_desaturase PF00487.24 EEQ36053.1 - 1.5e-15 57.7 21.0 1.5e-15 57.7 21.0 2.0 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EEQ36053.1 - 2.1e-13 50.2 0.0 4.1e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ThrE PF06738.12 EEQ36053.1 - 3.5 6.9 5.1 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Putative threonine/serine exporter CBS PF00571.28 EEQ36054.1 - 7.2e-25 87.2 0.6 4e-05 24.0 0.1 5.5 5 0 0 5 5 5 5 CBS domain GTP_EFTU PF00009.27 EEQ36055.1 - 8.4e-55 185.3 0.7 1.6e-54 184.4 0.0 1.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEQ36055.1 - 6.5e-43 145.6 0.0 1.4e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEQ36055.1 - 1.1e-13 51.4 2.2 1.1e-13 51.4 2.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ36055.1 - 0.0004 20.4 0.1 0.011 15.8 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GDC-P PF02347.16 EEQ36056.1 - 2e-189 629.9 0.0 1.2e-179 597.7 0.0 2.1 1 1 1 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EEQ36056.1 - 0.0058 15.6 0.0 0.016 14.2 0.0 1.7 1 0 0 1 1 1 1 Aminotransferase class-V Phage_tail_X PF05489.12 EEQ36056.1 - 0.04 13.6 0.0 0.42 10.3 0.0 2.5 2 0 0 2 2 2 0 Phage Tail Protein X WD40 PF00400.32 EEQ36057.1 - 4.9e-14 52.5 12.2 8.3e-05 23.3 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36057.1 - 1.8e-05 24.9 0.1 3.3 8.1 0.0 4.4 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L11 PF00298.19 EEQ36059.1 - 3.1e-28 98.1 0.6 4.5e-28 97.6 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EEQ36059.1 - 1.4e-26 92.1 0.3 2.2e-26 91.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 EEQ36060.1 - 1.6e-50 172.0 0.0 2.3e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36060.1 - 3.3e-24 85.6 0.0 4.9e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ36060.1 - 0.035 14.0 0.1 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEQ36060.1 - 0.056 12.4 0.0 0.056 12.4 0.0 2.0 3 0 0 3 3 3 0 Haspin like kinase domain adh_short PF00106.25 EEQ36061.1 - 4.8e-14 52.3 0.0 2e-08 33.9 0.0 2.6 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.10 EEQ36061.1 - 5.3e-09 36.2 0.0 9.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EEQ36061.1 - 3.3e-07 30.1 0.0 2.4e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase WD40 PF00400.32 EEQ36062.1 - 8.8e-12 45.4 1.6 0.0052 17.6 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36062.1 - 6.1e-08 32.9 0.0 0.0074 16.6 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EEQ36062.1 - 0.084 11.6 0.0 0.3 9.8 0.0 1.8 1 1 0 1 1 1 0 Nup133 N terminal like RAB3GAP2_N PF14655.6 EEQ36062.1 - 0.14 11.3 0.0 1.6 7.9 0.0 2.5 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus RRM_1 PF00076.22 EEQ36063.1 - 4.8e-07 29.5 0.0 4.8e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ36063.1 - 0.047 13.8 0.0 0.14 12.3 0.0 2.0 1 1 0 1 1 1 0 RNA recognition motif TP53IP5 PF15331.6 EEQ36063.1 - 0.34 11.0 18.7 0.14 12.3 0.3 2.1 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 RNA_pol_Rpc4 PF05132.14 EEQ36063.1 - 2.1 8.7 17.8 2.3 8.6 8.6 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ras PF00071.22 EEQ36065.1 - 9.5e-55 184.6 0.0 1.1e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ36065.1 - 2.1e-20 73.1 0.0 3.2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ36065.1 - 2.6e-09 36.7 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EEQ36065.1 - 0.11 12.4 0.2 12 5.8 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EEQ36065.1 - 0.15 11.5 0.0 0.37 10.3 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region SHR3_chaperone PF08229.11 EEQ36066.1 - 2e-66 222.5 0.2 2e-66 222.5 0.2 1.4 2 0 0 2 2 2 1 ER membrane protein SH3 Lysis_col PF02402.16 EEQ36067.1 - 4.5 7.0 7.0 25 4.6 2.0 2.6 2 0 0 2 2 2 0 Lysis protein Yippee-Mis18 PF03226.14 EEQ36068.1 - 2.2e-11 43.9 0.7 3.1e-11 43.4 0.7 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Eapp_C PF10238.9 EEQ36068.1 - 0.039 14.0 0.3 15 5.6 0.0 2.8 3 0 0 3 3 3 0 E2F-associated phosphoprotein Tnp_zf-ribbon_2 PF13842.6 EEQ36068.1 - 0.082 13.7 2.4 1.3 9.9 0.5 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon RIG-I_C-RD PF11648.8 EEQ36068.1 - 0.11 12.8 2.2 0.51 10.6 2.5 2.0 2 1 0 2 2 2 0 C-terminal domain of RIG-I UCH PF00443.29 EEQ36069.1 - 2.7e-52 177.8 0.1 2.7e-52 177.8 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ36069.1 - 1.1e-15 58.0 0.3 1.1e-15 58.0 0.3 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EEQ36069.1 - 0.0058 16.1 0.6 0.085 12.3 0.1 2.9 2 2 0 2 2 2 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase JAB PF01398.21 EEQ36070.1 - 5.8e-30 103.7 2.3 6.3e-30 103.6 0.1 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EEQ36070.1 - 5.4e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EEQ36070.1 - 0.0026 17.9 0.0 0.0026 17.9 0.0 2.3 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0172) L27 PF02828.16 EEQ36070.1 - 0.082 12.7 0.3 3.4 7.5 0.1 2.5 2 0 0 2 2 2 0 L27 domain PTPRCAP PF15713.5 EEQ36070.1 - 0.33 11.2 11.8 0.63 10.3 11.8 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated BNIP2 PF12496.8 EEQ36070.1 - 0.52 10.8 9.2 1.1 9.7 9.2 1.6 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF2457 PF10446.9 EEQ36070.1 - 2 7.4 18.1 3.3 6.7 18.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRM_1 PF00076.22 EEQ36071.1 - 5.4e-27 93.4 0.4 1.8e-14 53.3 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ36071.1 - 0.001 19.1 0.0 0.047 13.7 0.0 2.7 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EEQ36071.1 - 0.0024 17.5 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EEQ36071.1 - 0.027 14.3 0.5 4 7.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) RL PF17797.1 EEQ36071.1 - 0.089 12.7 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 RL domain Toxin_15 PF07906.13 EEQ36071.1 - 0.099 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 ShET2 enterotoxin, N-terminal region zf-H2C2_2 PF13465.6 EEQ36072.1 - 2.5e-09 37.2 15.1 1.7e-05 25.0 2.8 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EEQ36072.1 - 4.9e-08 33.0 14.9 0.00054 20.3 4.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ36072.1 - 0.00041 21.0 12.0 0.11 13.3 3.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEQ36072.1 - 0.014 15.3 0.9 7.7 6.7 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ36072.1 - 0.06 13.7 2.7 0.25 11.7 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EEQ36072.1 - 0.11 13.2 1.4 0.35 11.5 0.1 2.1 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-H2C2_5 PF13909.6 EEQ36072.1 - 7.2 6.5 13.3 3.2 7.6 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain HEAT_EZ PF13513.6 EEQ36073.1 - 1.7e-27 95.5 51.9 0.0025 18.3 0.4 16.8 16 3 4 20 20 16 9 HEAT-like repeat HEAT PF02985.22 EEQ36073.1 - 2.8e-22 76.9 35.4 0.0036 17.4 0.1 18.8 20 0 0 20 20 20 6 HEAT repeat Cnd1 PF12717.7 EEQ36073.1 - 3.8e-16 59.5 0.1 0.0014 18.7 0.0 10.0 8 2 4 12 12 12 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ36073.1 - 6.1e-16 58.6 59.6 0.026 14.9 0.2 13.5 7 3 7 16 16 16 6 HEAT repeats Vac14_Fab1_bd PF12755.7 EEQ36073.1 - 3.7e-13 49.9 0.0 0.079 13.6 0.0 9.2 10 2 1 12 12 10 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EEQ36073.1 - 2e-12 47.2 0.0 0.0078 15.8 0.0 6.6 5 2 2 7 7 7 3 CLASP N terminal Adaptin_N PF01602.20 EEQ36073.1 - 1.7e-11 43.4 0.0 1.6 7.2 0.0 8.4 7 2 1 9 9 9 2 Adaptin N terminal region MMS19_C PF12460.8 EEQ36073.1 - 2.3e-06 27.0 6.9 0.18 10.9 0.0 6.3 6 1 0 6 6 6 1 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 EEQ36073.1 - 0.00016 21.8 0.5 0.46 10.7 0.0 5.8 6 0 0 6 6 6 1 Required for nuclear transport of RNA pol II C-terminus 1 Ecm29 PF13001.7 EEQ36073.1 - 0.0026 16.5 0.3 9.4 4.8 0.0 4.7 5 1 1 6 6 6 0 Proteasome stabiliser Tti2 PF10521.9 EEQ36073.1 - 0.0052 16.4 0.0 3.5 7.1 0.0 4.6 5 0 0 5 5 5 1 Tti2 family IFRD PF05004.13 EEQ36073.1 - 0.0079 15.3 7.6 7 5.7 0.0 5.6 7 0 0 7 7 7 2 Interferon-related developmental regulator (IFRD) RIX1 PF08167.12 EEQ36073.1 - 0.0097 15.7 0.1 2.6 7.7 0.0 3.9 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 EEQ36073.1 - 0.018 14.9 0.0 2.4e+02 1.5 0.0 6.2 5 3 0 6 6 6 0 Domain of unknown function (DUF3385) Cohesin_HEAT PF12765.7 EEQ36073.1 - 0.035 14.4 11.3 8.3 6.8 0.1 5.9 7 0 0 7 7 4 0 HEAT repeat associated with sister chromatid cohesion ParcG PF10274.9 EEQ36073.1 - 0.037 14.1 0.1 72 3.4 0.0 5.0 5 1 1 6 6 6 0 Parkin co-regulated protein Gcn1_N PF12074.8 EEQ36073.1 - 0.039 13.3 4.2 0.84 8.9 0.1 3.2 2 1 1 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DRIM PF07539.12 EEQ36073.1 - 0.04 12.2 0.2 8.5 4.5 0.0 4.1 5 0 0 5 5 5 0 Down-regulated in metastasis Cnd3 PF12719.7 EEQ36073.1 - 0.05 12.8 0.3 55 2.8 0.0 4.5 5 0 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain TFCD_C PF12612.8 EEQ36073.1 - 0.21 11.4 0.7 3.6 7.4 0.0 3.2 2 1 1 3 3 3 0 Tubulin folding cofactor D C terminal ADSL_C PF10397.9 EEQ36073.1 - 0.23 12.0 4.0 0.63 10.6 0.0 3.7 4 0 0 4 4 4 0 Adenylosuccinate lyase C-terminus DUF2267 PF10025.9 EEQ36073.1 - 0.87 9.9 5.8 0.99 9.7 0.3 3.8 4 0 0 4 4 3 0 Uncharacterized conserved protein (DUF2267) Gcn1_N PF12074.8 EEQ36074.1 - 3.7e-71 240.3 19.1 7.8e-71 239.2 10.2 3.1 3 0 0 3 3 3 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EEQ36074.1 - 0.11 12.8 0.2 33 5.1 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat zf-HIT PF04438.16 EEQ36075.1 - 0.043 13.7 14.9 0.065 13.1 14.9 1.3 1 0 0 1 1 1 0 HIT zinc finger zf-CCCH PF00642.24 EEQ36076.1 - 2.4e-19 68.8 18.1 2.9e-11 43.0 1.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ36076.1 - 7.9e-08 32.1 21.4 3.9e-06 26.7 2.2 2.6 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 EEQ36076.1 - 7.4e-07 28.8 16.7 0.00041 20.1 0.9 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EEQ36076.1 - 0.0038 17.6 13.6 0.074 13.6 0.6 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EEQ36076.1 - 0.37 11.5 14.6 0.13 13.0 2.4 2.5 1 1 1 2 2 2 0 Torus domain oligo_HPY PF08352.12 EEQ36076.1 - 0.42 11.2 6.4 1.6 9.3 0.3 2.6 2 1 0 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region RQC PF09382.10 EEQ36078.1 - 4.7e-26 90.8 0.0 1.2e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.29 EEQ36078.1 - 4.5e-21 75.4 0.0 9.2e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ36078.1 - 6.3e-20 71.6 0.0 4.4e-16 59.2 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EEQ36078.1 - 1.6e-15 57.6 8.8 7.5e-15 55.4 8.8 2.3 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 EEQ36078.1 - 1e-08 35.0 0.0 2.3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Helicase_Sgs1 PF11408.8 EEQ36078.1 - 2.3e-08 33.9 0.1 6.7e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 Sgs1 RecQ helicase ResIII PF04851.15 EEQ36078.1 - 5.4e-05 23.3 0.0 0.00024 21.2 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HipN PF18253.1 EEQ36078.1 - 0.19 11.4 0.2 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain UQ_con PF00179.26 EEQ36079.1 - 1e-26 93.3 0.1 1.2e-26 93.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ36079.1 - 0.00018 21.2 0.0 0.00022 21.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EEQ36079.1 - 0.00042 20.2 0.1 0.00057 19.7 0.1 1.2 1 0 0 1 1 1 1 UEV domain Gal4_dimer PF03902.13 EEQ36080.1 - 2.6e-09 37.1 0.2 2.6e-09 37.1 0.2 1.8 2 0 0 2 2 2 1 Gal4-like dimerisation domain Zn_clus PF00172.18 EEQ36080.1 - 2.2e-08 34.1 17.6 5.3e-08 32.9 17.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RabGAP-TBC PF00566.18 EEQ36082.1 - 1.6e-46 158.7 3.8 1.6e-46 158.7 3.8 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain TPR_MLP1_2 PF07926.12 EEQ36082.1 - 0.00056 20.0 7.1 0.00056 20.0 7.1 3.7 3 1 1 4 4 3 1 TPR/MLP1/MLP2-like protein Leu_zip PF15294.6 EEQ36082.1 - 0.00067 19.3 5.6 0.00067 19.3 5.6 4.1 4 1 1 5 5 5 2 Leucine zipper Cnn_1N PF07989.11 EEQ36082.1 - 0.0016 18.6 0.8 0.0016 18.6 0.8 3.6 2 1 1 3 3 2 1 Centrosomin N-terminal motif 1 DUF2353 PF09789.9 EEQ36082.1 - 0.0032 16.9 14.3 0.011 15.1 14.3 1.9 1 1 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DUF4201 PF13870.6 EEQ36082.1 - 0.0048 16.7 6.6 0.0048 16.7 6.6 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4201) BRE1 PF08647.11 EEQ36082.1 - 0.0082 16.2 14.8 0.48 10.5 0.2 3.9 2 1 0 2 2 2 2 BRE1 E3 ubiquitin ligase Nup88 PF10168.9 EEQ36082.1 - 0.016 13.0 8.5 0.031 12.1 8.5 1.4 1 0 0 1 1 1 0 Nuclear pore component ATG16 PF08614.11 EEQ36082.1 - 0.017 15.3 15.5 0.017 15.3 15.5 3.0 2 2 1 3 3 2 0 Autophagy protein 16 (ATG16) Nas2_N PF18265.1 EEQ36082.1 - 0.096 12.6 0.7 0.47 10.4 0.7 2.2 1 1 0 1 1 1 0 Nas2 N_terminal domain TMPIT PF07851.13 EEQ36082.1 - 0.22 10.7 11.1 0.14 11.4 7.5 2.4 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 EEQ36082.1 - 1.1 9.3 10.7 0.06 13.4 2.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TolA_bind_tri PF16331.5 EEQ36082.1 - 2.1 8.5 10.9 1.2 9.3 5.1 3.2 1 1 1 2 2 2 0 TolA binding protein trimerisation bZIP_1 PF00170.21 EEQ36082.1 - 2.4 8.3 19.8 0.46 10.6 0.1 4.0 4 1 1 5 5 4 0 bZIP transcription factor Latarcin PF10279.9 EEQ36082.1 - 3.6 8.1 8.3 0.63 10.5 0.7 2.8 2 0 0 2 2 2 0 Latarcin precursor FlaC_arch PF05377.11 EEQ36082.1 - 6.3 7.3 13.3 13 6.3 0.7 4.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) CtIP_N PF10482.9 EEQ36082.1 - 6.5 6.8 14.2 25 4.9 11.1 2.8 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Herpes_BLRF2 PF05812.12 EEQ36082.1 - 7.6 6.7 11.6 2.5 8.2 0.9 3.6 2 1 1 3 3 3 0 Herpesvirus BLRF2 protein FapA PF03961.13 EEQ36082.1 - 8.9 4.8 11.6 0.62 8.6 3.1 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A COG2 PF06148.11 EEQ36082.1 - 9.4 6.3 12.4 0.18 11.9 4.1 2.5 3 1 0 3 3 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Ribosomal_S4e PF00900.20 EEQ36083.1 - 1.7e-35 120.7 0.5 3.2e-35 119.9 0.5 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EEQ36083.1 - 8.2e-25 86.2 0.0 1.6e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EEQ36083.1 - 2e-21 75.8 6.2 1.1e-20 73.4 6.4 2.1 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 EEQ36083.1 - 7.3e-08 32.0 0.0 1.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EEQ36083.1 - 2.7e-05 24.0 3.8 2.7e-05 24.0 3.8 3.0 3 0 0 3 3 3 1 KOW motif Sipho_tail PF05709.11 EEQ36083.1 - 0.047 13.1 0.2 0.15 11.5 0.2 1.7 1 1 0 1 1 1 0 Phage tail protein 5_nucleotid_C PF02872.18 EEQ36084.1 - 0.02 15.1 0.0 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain GATA PF00320.27 EEQ36085.1 - 1.5e-08 34.1 6.7 1.5e-08 34.1 6.7 1.7 2 0 0 2 2 2 1 GATA zinc finger ADD_DNMT3 PF17980.1 EEQ36085.1 - 0.023 14.7 1.0 0.064 13.3 0.1 2.1 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 DZR PF12773.7 EEQ36085.1 - 0.065 13.3 5.7 2.1 8.4 5.8 2.6 1 1 1 2 2 2 0 Double zinc ribbon ubiquitin PF00240.23 EEQ36086.1 - 6.6e-23 80.3 0.1 9.5e-23 79.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EEQ36086.1 - 7.8e-11 41.7 0.1 1.2e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 EEQ36086.1 - 5.3e-07 29.4 0.5 3.2e-06 26.9 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.9 EEQ36086.1 - 0.00048 20.6 0.0 0.00074 20.0 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEQ36086.1 - 0.0016 18.6 0.1 0.0038 17.3 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RPN13_C PF16550.5 EEQ36086.1 - 0.017 15.3 0.1 0.032 14.4 0.1 1.4 1 0 0 1 1 1 0 UCH-binding domain Ubiquitin_2 PF14560.6 EEQ36086.1 - 0.017 15.6 0.1 0.038 14.4 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 EEQ36086.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 EEQ36086.1 - 0.018 15.0 0.1 0.2 11.8 0.1 2.1 1 1 1 2 2 2 0 Ubiquitin-like domain HOIP-UBA PF16678.5 EEQ36086.1 - 0.031 14.3 0.1 0.075 13.0 0.0 1.6 2 0 0 2 2 2 0 HOIP UBA domain pair STI1 PF17830.1 EEQ36086.1 - 3 7.8 14.5 4.6 7.3 3.5 2.6 1 1 1 2 2 2 0 STI1 domain TAF8_C PF10406.9 EEQ36087.1 - 2.1e-16 60.2 0.5 2.1e-16 60.2 0.5 3.5 4 0 0 4 4 4 1 Transcription factor TFIID complex subunit 8 C-term NIF PF03031.18 EEQ36088.1 - 1.6e-27 96.2 0.0 5.6e-26 91.2 0.0 2.5 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EEQ36088.1 - 4.6e-05 23.7 0.0 0.00015 22.1 0.0 1.9 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEQ36088.1 - 0.0036 17.2 0.0 0.016 15.1 0.0 2.1 2 1 0 2 2 2 1 twin BRCT domain BRCT_2 PF16589.5 EEQ36088.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain SUR7 PF06687.12 EEQ36089.1 - 1.2e-56 191.7 2.9 1.5e-56 191.4 2.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF973 PF06157.11 EEQ36089.1 - 0.014 14.4 1.8 0.035 13.2 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF973) T4SS PF07996.11 EEQ36089.1 - 0.15 12.5 0.2 0.24 11.8 0.2 1.3 1 0 0 1 1 1 0 Type IV secretion system proteins DUF902 PF06001.13 EEQ36089.1 - 1.5 9.4 10.0 2.8 8.5 0.9 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) LapA_dom PF06305.11 EEQ36089.1 - 1.9 8.4 0.0 1.9 8.4 0.0 3.2 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain Prp19 PF08606.11 EEQ36090.1 - 3.1e-30 104.0 2.5 5.7e-30 103.1 2.5 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.15 EEQ36090.1 - 6.1e-05 23.1 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain Coatomer_WDAD PF04053.14 EEQ36090.1 - 0.019 14.0 0.1 0.12 11.3 0.0 2.0 1 1 0 1 1 1 0 Coatomer WD associated region DUF1635 PF07795.11 EEQ36090.1 - 0.084 12.7 0.4 0.14 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) zf-Nse PF11789.8 EEQ36090.1 - 0.11 12.3 0.0 0.36 10.7 0.0 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit PGM_PMM_I PF02878.16 EEQ36091.1 - 3.7e-33 114.2 0.3 3.6e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EEQ36091.1 - 1.7e-25 89.6 0.0 3.8e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EEQ36091.1 - 7.8e-16 58.3 0.0 2.8e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EEQ36091.1 - 3.2e-06 27.2 0.0 9.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Anp1 PF03452.14 EEQ36092.1 - 3.8e-112 374.0 0.0 4.9e-112 373.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 Yip1 PF04893.17 EEQ36093.1 - 1.5e-11 44.3 15.1 2.3e-11 43.7 15.1 1.2 1 0 0 1 1 1 1 Yip1 domain Hexapep PF00132.24 EEQ36094.1 - 8.9e-14 50.6 11.5 3.4e-11 42.4 5.2 2.7 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EEQ36094.1 - 1.1e-12 47.5 12.7 1.2e-09 37.7 5.0 2.6 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EEQ36094.1 - 3.3e-07 30.5 0.0 5.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Aldo_ket_red PF00248.21 EEQ36095.1 - 8.3e-32 110.5 0.1 2.9e-30 105.5 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Kelch_6 PF13964.6 EEQ36097.1 - 6.5e-09 35.8 1.0 0.0019 18.4 0.0 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EEQ36097.1 - 1.5e-08 34.7 0.0 0.0021 18.3 0.0 2.9 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_4 PF13418.6 EEQ36097.1 - 9.9e-06 25.5 0.5 0.0088 16.0 0.0 4.7 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EEQ36097.1 - 2.2e-05 24.3 0.0 1.3 9.1 0.0 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EEQ36097.1 - 0.00031 20.3 0.0 0.029 14.0 0.0 3.7 5 0 0 5 5 5 1 Kelch motif Big_5 PF13205.6 EEQ36097.1 - 0.18 12.5 1.0 11 6.8 0.1 2.8 3 0 0 3 3 3 0 Bacterial Ig-like domain Kelch_2 PF07646.15 EEQ36097.1 - 0.47 10.5 7.8 1.1 9.3 0.2 4.9 5 2 0 5 5 5 0 Kelch motif Eisosome1 PF12757.7 EEQ36098.1 - 2.9e-13 50.2 0.2 2.9e-13 50.2 0.2 7.8 5 3 3 8 8 8 1 Eisosome protein 1 ADH_N PF08240.12 EEQ36100.1 - 3e-28 97.9 0.6 7.3e-28 96.6 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ36100.1 - 1.8e-27 95.9 0.6 3.2e-27 95.1 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ36100.1 - 2.7e-08 34.9 0.1 4.4e-08 34.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEQ36100.1 - 0.00054 19.5 0.7 0.00079 19.0 0.7 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus RRM_1 PF00076.22 EEQ36101.1 - 2.9e-24 84.7 0.1 6.6e-17 61.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ36101.1 - 0.0093 16.1 0.0 0.21 11.7 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif CSRNP_N PF16019.5 EEQ36101.1 - 0.16 11.9 8.6 0.3 11.0 8.6 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF2052 PF09747.9 EEQ36101.1 - 0.25 11.5 20.1 0.21 11.7 11.5 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) DNA_pol_phi PF04931.13 EEQ36101.1 - 0.48 8.5 19.2 0.69 7.9 19.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi SpoIIIAH PF12685.7 EEQ36101.1 - 0.87 9.4 12.7 1.6 8.5 12.7 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 EEQ36101.1 - 3.4 6.8 3.8 5 6.2 3.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2151 PF10221.9 EEQ36101.1 - 7.3 5.0 17.3 0.11 11.0 9.5 1.8 2 0 0 2 2 2 0 Cell cycle and development regulator PPL5 PF18168.1 EEQ36101.1 - 9.4 5.4 8.6 22 4.2 8.6 1.6 1 0 0 1 1 1 0 Prim-pol family 5 DUF2838 PF10998.8 EEQ36102.1 - 1.6e-37 128.2 12.8 1.6e-37 128.2 12.8 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) Striatin PF08232.12 EEQ36102.1 - 0.074 13.6 0.3 0.074 13.6 0.3 2.2 2 0 0 2 2 2 0 Striatin family Pinin_SDK_memA PF04696.13 EEQ36102.1 - 6.3 6.9 12.0 0.14 12.2 4.2 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Ribosomal_S5_C PF03719.15 EEQ36103.1 - 1.2e-25 88.7 0.0 2.2e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EEQ36103.1 - 1e-20 73.5 0.0 1.7e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DUF1611_N PF17396.2 EEQ36103.1 - 0.13 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_N) Rossmann-like domain HisKA PF00512.25 EEQ36103.1 - 0.17 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DnaJ-X PF14308.6 EEQ36104.1 - 9.7e-86 286.6 15.2 9.7e-86 286.6 15.2 2.9 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.31 EEQ36104.1 - 2.4e-25 88.4 0.7 9.2e-25 86.6 0.7 2.1 1 0 0 1 1 1 1 DnaJ domain Takusan PF04822.13 EEQ36104.1 - 0.0045 16.8 15.1 0.31 11.0 4.8 2.6 2 0 0 2 2 2 2 Takusan Peptidase_S30 PF01577.16 EEQ36104.1 - 4.1 7.0 13.6 0.27 10.8 6.0 2.3 2 0 0 2 2 2 0 Potyvirus P1 protease DOPA_dioxygen PF08883.11 EEQ36105.1 - 3.5e-30 104.3 0.2 4.3e-30 104.0 0.2 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family BAG PF02179.16 EEQ36106.1 - 5.5e-24 84.4 0.2 1.4e-23 83.1 0.2 1.7 1 0 0 1 1 1 1 BAG domain PDE4_UCR PF18100.1 EEQ36106.1 - 0.0048 17.5 0.3 0.013 16.1 0.1 1.8 1 1 0 1 1 1 1 Phosphodiesterase 4 upstream conserved regions (UCR) 30K_MP_C_Ter PF11330.8 EEQ36106.1 - 0.018 14.4 0.1 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 C-Terminal of 30K viral movement proteins DUF4363 PF14276.6 EEQ36106.1 - 0.085 13.0 0.3 0.085 13.0 0.3 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Sedlin_N PF04628.13 EEQ36108.1 - 6.7e-21 74.8 0.1 8e-21 74.5 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EEQ36108.1 - 5.9e-06 26.3 0.0 7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family YL1_C PF08265.11 EEQ36109.1 - 1.8e-12 46.8 0.0 3.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Epimerase PF01370.21 EEQ36110.1 - 1.7e-16 60.5 0.0 2.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ36110.1 - 2.4e-09 36.6 0.0 3.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEQ36110.1 - 8.7e-08 31.9 0.0 1.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EEQ36110.1 - 1.7e-07 31.3 0.1 2.5e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 EEQ36110.1 - 0.00026 21.5 0.1 0.0044 17.6 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 EEQ36110.1 - 0.0029 16.8 0.0 0.41 9.8 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 EEQ36110.1 - 0.0033 17.4 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EEQ36110.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.20 EEQ36110.1 - 0.03 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 EEQ36110.1 - 0.044 13.3 0.0 0.091 12.3 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 EEQ36110.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FAD-oxidase_C PF02913.19 EEQ36111.1 - 2e-50 171.8 0.0 3.4e-50 171.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EEQ36111.1 - 1.5e-30 105.7 0.3 2.9e-30 104.8 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain PFOR_II PF17147.4 EEQ36112.1 - 0.0014 18.9 0.3 0.003 17.8 0.3 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II RMMBL PF07521.12 EEQ36112.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain FAD_binding_1 PF00667.20 EEQ36115.1 - 8.2e-32 110.6 0.0 1.5e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 EEQ36115.1 - 8.5e-05 22.7 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase DEAD PF00270.29 EEQ36115.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase FAD_binding_1 PF00667.20 EEQ36116.1 - 1.9e-32 112.7 0.1 2.6e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEQ36116.1 - 1.4e-08 35.4 0.0 3.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ36116.1 - 0.014 15.7 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEQ36116.1 - 0.032 14.3 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Anticodon_1 PF08264.13 EEQ36116.1 - 0.11 12.5 0.7 4.9 7.1 0.1 2.7 2 1 0 2 2 2 0 Anticodon-binding domain of tRNA Flocculin_t3 PF13928.6 EEQ36119.1 - 7.6e-39 132.0 85.8 2.8e-13 50.1 15.5 7.3 6 2 2 8 8 8 4 Flocculin type 3 repeat AF-4 PF05110.13 EEQ36119.1 - 0.07 11.2 5.7 0.09 10.9 5.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Vanabin-2 PF11437.8 EEQ36119.1 - 0.54 10.4 10.8 0.85 9.8 2.5 2.6 2 0 0 2 2 2 0 Vanadium-binding protein 2 FANCL_C PF11793.8 EEQ36119.1 - 3.3 8.0 9.0 62 3.9 0.2 4.4 4 0 0 4 4 4 0 FANCL C-terminal domain G10 PF01125.17 EEQ36120.1 - 5.8e-61 204.6 8.6 6.4e-61 204.4 8.6 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 EEQ36121.1 - 1.1e-35 121.7 0.1 1.9e-35 121.0 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain TFIIE_alpha PF02002.17 EEQ36122.1 - 9.7e-25 86.5 0.9 1e-22 80.0 0.2 2.4 2 0 0 2 2 2 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 EEQ36122.1 - 0.0003 20.2 0.4 0.0011 18.4 0.4 2.0 1 1 0 1 1 1 1 TFIIB zinc-binding zf-TFIIB PF13453.6 EEQ36122.1 - 0.0033 16.7 0.4 0.0077 15.5 0.4 1.6 1 0 0 1 1 1 1 Transcription factor zinc-finger zf_UBZ PF18439.1 EEQ36122.1 - 0.011 15.3 0.6 0.14 11.8 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4946 PF16304.5 EEQ36122.1 - 0.028 14.1 0.3 0.045 13.5 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) MAGE_N PF12440.8 EEQ36122.1 - 0.031 14.9 3.1 0.031 14.9 3.1 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal DUF4428 PF14471.6 EEQ36122.1 - 0.04 13.8 1.3 0.16 11.9 1.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) PhnA_Zn_Ribbon PF08274.12 EEQ36122.1 - 1.2 9.2 3.0 5.4 7.1 0.1 2.6 3 0 0 3 3 3 0 PhnA Zinc-Ribbon SR-25 PF10500.9 EEQ36122.1 - 1.2 8.7 10.9 0.28 10.7 7.9 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SKIP_SNW PF02731.15 EEQ36122.1 - 5.9 6.5 10.7 0.24 11.1 1.4 2.9 3 0 0 3 3 3 0 SKIP/SNW domain DUF2370 PF10176.9 EEQ36123.1 - 5e-79 265.1 0.4 1.3e-78 263.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) SurE PF01975.17 EEQ36124.1 - 2.9e-10 40.2 0.0 1.8e-08 34.4 0.0 2.9 1 1 0 1 1 1 1 Survival protein SurE Glyco_transf_5 PF08323.11 EEQ36124.1 - 0.0037 17.0 0.2 0.35 10.5 0.0 2.2 2 0 0 2 2 2 2 Starch synthase catalytic domain CCM2_C PF16545.5 EEQ36124.1 - 0.068 13.7 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology AA_permease_2 PF13520.6 EEQ36125.1 - 5.1e-61 206.8 34.3 1.5e-60 205.2 34.3 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ36125.1 - 1.1e-07 30.9 27.3 1.1e-07 30.9 27.3 1.6 2 0 0 2 2 2 1 Amino acid permease Rad1 PF02144.16 EEQ36126.1 - 1.2e-50 172.1 3.7 1.5e-50 171.8 3.7 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 vATP-synt_AC39 PF01992.16 EEQ36127.1 - 4.4e-78 263.1 0.7 5.3e-78 262.9 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Dor1 PF04124.12 EEQ36128.1 - 6.2e-21 74.5 14.4 1.4e-20 73.2 14.4 1.5 1 0 0 1 1 1 1 Dor1-like family LPD3 PF18798.1 EEQ36128.1 - 0.066 13.5 0.2 3.9 7.7 0.1 2.7 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 3 RE_TdeIII PF09520.10 EEQ36128.1 - 0.097 12.3 4.0 0.17 11.5 4.0 1.4 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII COMMD1_N PF17221.3 EEQ36128.1 - 2.6 8.4 6.5 3 8.2 0.6 2.9 2 1 1 3 3 3 0 COMMD1 N-terminal domain UPF0184 PF03670.13 EEQ36128.1 - 2.9 8.3 9.0 0.74 10.2 0.1 3.7 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0184) Helicase_C PF00271.31 EEQ36129.1 - 1.6e-19 70.3 0.0 4.2e-19 68.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 EEQ36129.1 - 0.00069 19.9 7.9 0.0011 19.2 7.3 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ36129.1 - 0.0011 18.8 1.3 0.0027 17.5 1.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ36129.1 - 0.0033 17.4 8.1 0.0092 15.9 8.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEQ36129.1 - 0.0036 17.3 4.5 0.0076 16.3 4.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEQ36129.1 - 0.0078 16.1 8.9 0.015 15.1 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ssu72 PF04722.13 EEQ36129.1 - 0.0082 15.7 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 Ssu72-like protein zf-RING_11 PF17123.5 EEQ36129.1 - 0.016 15.0 0.7 0.016 15.0 0.7 2.2 2 0 0 2 2 2 0 RING-like zinc finger Eapp_C PF10238.9 EEQ36129.1 - 0.016 15.3 0.3 6 6.9 0.3 2.5 2 0 0 2 2 2 0 E2F-associated phosphoprotein FYVE PF01363.21 EEQ36129.1 - 0.41 10.8 7.2 0.14 12.3 4.6 1.6 2 0 0 2 2 2 0 FYVE zinc finger Prok-RING_4 PF14447.6 EEQ36129.1 - 0.46 10.4 12.2 23 5.0 12.1 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 SNF2_N PF00176.23 EEQ36130.1 - 9.9e-58 195.5 0.2 2.2e-57 194.4 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EEQ36130.1 - 1.1e-08 35.3 0.1 3.2e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TPR_2 PF07719.17 EEQ36131.1 - 1.4e-06 28.0 2.5 7.9e-05 22.5 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ36131.1 - 1.3e-05 24.8 2.9 3.7e-05 23.3 0.6 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ36131.1 - 0.0029 17.3 0.2 0.0084 15.8 0.2 1.8 1 0 0 1 1 1 1 TPR repeat MotY_N PF18393.1 EEQ36131.1 - 0.0056 16.8 0.0 0.0092 16.1 0.0 1.3 1 0 0 1 1 1 1 MotY N-terminal domain TPR_9 PF13371.6 EEQ36131.1 - 0.023 14.8 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ36131.1 - 0.092 13.0 0.3 0.5 10.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36131.1 - 0.13 13.1 0.0 0.47 11.4 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HTH_WhiA PF02650.14 EEQ36131.1 - 0.15 12.4 0.1 0.29 11.5 0.1 1.4 1 0 0 1 1 1 0 WhiA C-terminal HTH domain Aminotran_1_2 PF00155.21 EEQ36133.1 - 1.6e-59 201.9 0.0 1.8e-59 201.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEQ36133.1 - 0.0014 17.2 0.0 0.0035 15.9 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme CPBP PF02517.16 EEQ36134.1 - 0.042 14.2 2.8 0.69 10.3 0.2 2.7 2 1 0 2 2 2 0 CPBP intramembrane metalloprotease DUF3413 PF11893.8 EEQ36134.1 - 0.077 12.2 0.3 0.077 12.2 0.3 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) Ion_trans_2 PF07885.16 EEQ36135.1 - 3.8e-26 90.8 24.6 8.2e-16 57.7 10.1 4.1 4 1 0 4 4 4 2 Ion channel Phage_holin_3_6 PF07332.11 EEQ36135.1 - 2.8 8.0 10.9 7.7 6.6 0.0 3.9 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Nucleoside_tran PF01733.18 EEQ36136.1 - 5.8e-47 160.6 18.1 1.4e-46 159.3 18.1 1.7 1 1 0 1 1 1 1 Nucleoside transporter Peptidase_C92 PF05708.12 EEQ36137.1 - 0.089 12.9 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Diphthamide_syn PF01866.17 EEQ36138.1 - 1.1e-66 225.3 0.0 3.5e-66 223.7 0.0 1.7 2 0 0 2 2 2 1 Putative diphthamide synthesis protein ALMT PF11744.8 EEQ36138.1 - 0.0047 15.8 1.4 0.0047 15.8 1.4 1.4 2 0 0 2 2 2 1 Aluminium activated malate transporter adh_short PF00106.25 EEQ36139.1 - 8.5e-33 113.5 0.0 1.5e-32 112.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ36139.1 - 6.1e-19 68.5 0.0 7.8e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ36139.1 - 3.2e-06 27.2 1.0 8.8e-05 22.5 1.0 2.2 1 1 0 1 1 1 1 KR domain zf-RING_UBOX PF13445.6 EEQ36140.1 - 6.1e-07 29.4 2.5 1.6e-06 28.1 2.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ36140.1 - 4.5e-06 26.5 3.6 1.2e-05 25.2 3.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EEQ36140.1 - 4.5e-06 26.4 6.1 9.4e-06 25.4 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ36140.1 - 0.00011 22.5 7.0 0.00026 21.3 7.0 1.7 1 1 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EEQ36140.1 - 0.0002 21.1 11.2 0.21 11.5 7.2 3.2 1 1 2 3 3 3 2 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EEQ36140.1 - 0.00029 20.6 5.8 0.00039 20.2 2.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ36140.1 - 0.00033 20.4 4.5 0.0012 18.7 4.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ36140.1 - 0.0066 16.6 5.8 0.018 15.2 5.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING TFR_dimer PF04253.15 EEQ36141.1 - 3.6e-16 59.4 0.1 7.3e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EEQ36141.1 - 2.1e-08 34.1 0.0 3.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 OCD_Mu_crystall PF02423.15 EEQ36141.1 - 0.12 11.3 0.0 16 4.3 0.0 2.8 3 0 0 3 3 3 0 Ornithine cyclodeaminase/mu-crystallin family ChaC PF04752.12 EEQ36142.1 - 9e-52 175.7 0.0 9.2e-51 172.4 0.0 2.0 1 1 0 1 1 1 1 ChaC-like protein Na_H_Exchanger PF00999.21 EEQ36143.1 - 3.9e-67 226.7 16.5 4.8e-67 226.4 16.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 EEQ36143.1 - 1.5e-61 209.0 31.2 3.8e-55 187.9 19.0 2.0 1 1 1 2 2 2 2 Alkali metal cation/H+ antiporter Nha1 C terminus Aminotran_3 PF00202.21 EEQ36144.1 - 8.4e-121 403.4 0.0 9.8e-121 403.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 EEQ36144.1 - 0.014 14.7 0.0 0.044 13.1 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EEQ36144.1 - 0.018 14.2 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II RNR_inhib PF08591.10 EEQ36145.1 - 1.2e-07 33.0 0.3 2.2e-07 32.1 0.3 1.6 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF4527 PF15030.6 EEQ36145.1 - 0.091 12.2 0.3 0.1 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) SUR7 PF06687.12 EEQ36146.1 - 6.6e-07 29.2 5.8 9.8e-07 28.6 1.4 2.3 2 0 0 2 2 2 1 SUR7/PalI family Fig1 PF12351.8 EEQ36146.1 - 2.9 7.8 11.5 0.12 12.3 5.2 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF5076 PF16826.5 EEQ36147.1 - 0.17 11.8 0.0 0.32 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5076) Cys_Met_Meta_PP PF01053.20 EEQ36148.1 - 2.7e-146 487.0 0.0 3.1e-146 486.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EEQ36148.1 - 6e-10 38.6 0.1 9e-10 38.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ36148.1 - 9.7e-10 38.3 0.0 1.9e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EEQ36148.1 - 3e-09 36.5 0.0 5.6e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 EEQ36148.1 - 1.6e-05 23.6 0.1 2.3e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EEQ36148.1 - 0.0004 19.8 0.0 0.00067 19.0 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.16 EEQ36148.1 - 0.0083 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Asparaginase_C PF17763.1 EEQ36148.1 - 0.023 14.9 0.0 0.057 13.6 0.0 1.6 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Radical_SAM PF04055.21 EEQ36148.1 - 0.032 14.6 0.0 0.57 10.5 0.0 2.6 3 0 0 3 3 3 0 Radical SAM superfamily MUG113 PF13455.6 EEQ36149.1 - 4e-08 33.8 0.8 3.4e-07 30.8 0.8 2.4 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EEQ36149.1 - 4.3e-06 27.2 5.3 0.0003 21.3 1.0 3.5 2 1 0 3 3 3 2 T5orf172 domain zf-primase PF09329.11 EEQ36149.1 - 0.0024 17.7 0.9 0.0055 16.5 0.9 1.6 1 0 0 1 1 1 1 Primase zinc finger DUF4268 PF14088.6 EEQ36149.1 - 0.076 12.9 0.2 4 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4268) Helicase_C PF00271.31 EEQ36150.1 - 3.6e-25 88.5 1.0 1.5e-24 86.5 0.1 2.4 3 1 1 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ36150.1 - 7.8e-18 64.8 0.0 2.1e-17 63.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase STI1 PF17830.1 EEQ36151.1 - 0.077 12.9 0.2 0.3 11.1 0.2 2.0 1 1 1 2 2 2 0 STI1 domain ComZ PF10815.8 EEQ36151.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 ComZ Mononeg_mRNAcap PF14318.6 EEQ36152.1 - 0.058 12.6 0.5 0.097 11.9 0.5 1.3 1 0 0 1 1 1 0 Mononegavirales mRNA-capping region V P5CR_dimer PF14748.6 EEQ36153.1 - 1.3e-34 118.5 3.2 1.7e-34 118.2 2.0 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EEQ36153.1 - 1.2e-12 48.2 0.2 3.8e-12 46.6 0.0 2.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EEQ36153.1 - 0.0011 19.0 0.0 0.0032 17.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 EEQ36153.1 - 0.0025 17.8 0.2 0.009 16.0 0.2 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EEQ36153.1 - 0.0033 17.1 0.0 0.018 14.7 0.0 2.0 1 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA IMPa_N_2 PF18650.1 EEQ36153.1 - 0.022 14.0 0.0 0.034 13.4 0.0 1.2 1 0 0 1 1 1 0 Immunomodulating metalloprotease N-terminal domain JmjC PF02373.22 EEQ36154.1 - 1.7e-38 131.5 0.1 4.9e-38 130.1 0.1 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EEQ36154.1 - 3.3e-12 46.1 7.2 3.3e-12 46.1 7.2 2.2 2 0 0 2 2 2 1 PHD-finger JmjN PF02375.17 EEQ36154.1 - 3.7e-09 36.4 0.0 1.1e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 jmjN domain PHD_2 PF13831.6 EEQ36154.1 - 0.0055 16.2 1.5 0.019 14.5 1.5 2.0 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EEQ36154.1 - 3.9 7.8 9.4 0.52 10.6 1.7 3.0 3 0 0 3 3 3 0 PHD-like zinc-binding domain Zf_RING PF16744.5 EEQ36154.1 - 9.3 6.4 8.5 39 4.5 3.5 3.0 3 0 0 3 3 3 0 KIAA1045 RING finger ATP-synt_ab PF00006.25 EEQ36155.1 - 1.1e-62 211.4 0.0 1.6e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATPase PF06745.13 EEQ36155.1 - 0.0036 16.7 0.3 0.0069 15.8 0.3 1.5 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 EEQ36155.1 - 0.0089 15.2 0.7 0.058 12.6 0.1 2.0 2 0 0 2 2 2 1 NB-ARC domain RsgA_GTPase PF03193.16 EEQ36155.1 - 0.03 14.2 0.1 0.06 13.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase T3SS_ATPase_C PF18269.1 EEQ36155.1 - 0.033 14.0 0.6 0.2 11.5 0.6 2.1 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NACHT PF05729.12 EEQ36155.1 - 0.037 13.9 0.3 0.094 12.6 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.6 EEQ36155.1 - 0.05 13.9 0.9 0.38 11.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 EEQ36155.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA PF00004.29 EEQ36155.1 - 0.081 13.3 0.1 1.8 9.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ36155.1 - 0.083 13.3 0.2 0.28 11.6 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EEQ36155.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATP-synt_ab_N PF02874.23 EEQ36155.1 - 0.17 12.4 1.9 0.26 11.8 0.5 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, beta-barrel domain TsaE PF02367.17 EEQ36155.1 - 0.18 11.8 0.1 0.42 10.6 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EEQ36155.1 - 0.18 11.7 0.0 0.79 9.6 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 EEQ36155.1 - 0.23 10.9 0.1 0.39 10.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein DnaJ PF00226.31 EEQ36156.1 - 3.1e-11 43.2 3.3 3.2e-11 43.2 0.4 2.3 2 0 0 2 2 2 1 DnaJ domain MalF_P2 PF14785.6 EEQ36156.1 - 0.12 12.4 4.1 0.15 12.1 4.1 1.3 1 1 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain RR_TM4-6 PF06459.12 EEQ36156.1 - 0.55 10.0 10.2 0.68 9.7 10.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 O-antigen_lig PF13425.6 EEQ36156.1 - 5.9 5.6 7.4 7.4 5.2 7.4 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TatD_DNase PF01026.21 EEQ36157.1 - 8.7e-40 136.7 0.0 7.7e-39 133.6 0.0 2.0 1 1 0 1 1 1 1 TatD related DNase MOZ_SAS PF01853.18 EEQ36158.1 - 1.2e-71 240.1 0.6 1.7e-71 239.6 0.6 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EEQ36158.1 - 8.8e-21 73.3 4.0 2.1e-20 72.0 4.0 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EEQ36158.1 - 0.012 16.1 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2457 PF10446.9 EEQ36158.1 - 0.023 13.9 34.4 0.064 12.4 34.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-C2H2_jaz PF12171.8 EEQ36158.1 - 0.043 14.1 0.5 0.083 13.2 0.5 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PP2C PF00481.21 EEQ36159.1 - 1.1e-76 257.9 0.0 2e-76 257.0 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C RRM_1 PF00076.22 EEQ36160.1 - 1.1e-06 28.3 0.1 2.5e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_2b PF00587.25 EEQ36162.1 - 1.6e-32 112.9 0.0 2.3e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEQ36162.1 - 3.9e-06 26.9 0.0 7.3e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.20 EEQ36162.1 - 0.046 12.8 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) RNR_Alpha PF17975.1 EEQ36163.1 - 0.44 11.1 4.9 0.17 12.4 0.6 2.5 1 1 0 2 2 2 0 Ribonucleotide reductase alpha domain DUF1752 PF08550.10 EEQ36164.1 - 0.0076 16.1 1.4 0.02 14.7 1.4 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DnaJ PF00226.31 EEQ36165.1 - 2.8e-24 85.0 0.2 1.3e-23 82.9 0.2 2.3 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 EEQ36165.1 - 3.5e-08 33.5 10.2 3.5e-08 33.5 10.2 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ36165.1 - 4.5e-08 33.2 11.6 5e-07 29.9 5.5 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EEQ36165.1 - 1.3e-06 28.7 11.3 0.0021 18.3 5.5 2.9 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EEQ36165.1 - 4e-05 24.1 8.5 0.076 13.9 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ36165.1 - 0.0011 19.3 12.1 0.063 13.8 2.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF4136 PF13590.6 EEQ36165.1 - 0.36 11.4 6.6 0.56 10.8 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4136) EHN PF06441.12 EEQ36165.1 - 1.4 9.3 7.7 1.4 9.3 4.8 2.5 1 1 1 2 2 2 0 Epoxide hydrolase N terminus Imm74 PF15603.6 EEQ36165.1 - 3.4 7.9 7.5 1 9.6 1.9 2.7 3 0 0 3 3 3 0 Immunity protein 74 G-patch PF01585.23 EEQ36166.1 - 7.1e-12 45.0 3.3 8.7e-12 44.7 1.8 2.0 2 0 0 2 2 2 1 G-patch domain Caldesmon PF02029.15 EEQ36167.1 - 0.72 8.6 34.3 0.94 8.2 34.3 1.2 1 0 0 1 1 1 0 Caldesmon Peptidase_C54 PF03416.19 EEQ36168.1 - 1.2e-76 257.8 0.0 1.5e-76 257.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.13 EEQ36169.1 - 1.3e-82 276.0 0.6 1.5e-82 275.8 0.6 1.0 1 0 0 1 1 1 1 Ssu72-like protein POP1 PF06978.11 EEQ36170.1 - 3.3e-70 236.3 12.0 4.6e-70 235.8 12.0 1.2 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EEQ36170.1 - 6.5e-16 58.4 0.5 1.6e-15 57.2 0.5 1.6 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T_C PF08669.11 EEQ36170.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain YCII PF03795.14 EEQ36171.1 - 9.7e-06 25.9 0.0 1.2e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Flocculin_t3 PF13928.6 EEQ36172.1 - 0.00011 22.6 7.9 0.00011 22.6 7.9 2.9 2 1 0 2 2 2 1 Flocculin type 3 repeat DUF1505 PF07403.11 EEQ36172.1 - 0.02 15.0 2.5 0.023 14.9 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1505) UCH PF00443.29 EEQ36173.1 - 6.8e-48 163.4 0.3 1.5e-47 162.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ36173.1 - 1.5e-07 31.3 2.8 0.0011 18.6 0.0 2.8 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase PH_18 PF18469.1 EEQ36175.1 - 3.3e-48 163.3 0.0 6.6e-48 162.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Rtt106 PF08512.12 EEQ36175.1 - 6.7e-19 68.1 0.1 4.2e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Rtt106_N PF18215.1 EEQ36175.1 - 3.9e-06 26.5 0.0 7.3e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Histone chaperone Rtt106 N-terminal domain Aminotran_1_2 PF00155.21 EEQ36177.1 - 1.2e-21 77.3 0.0 1.6e-21 76.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EEQ36177.1 - 0.025 13.4 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase PX PF00787.24 EEQ36178.1 - 3.3e-14 52.8 0.0 8.6e-14 51.5 0.0 1.6 1 0 0 1 1 1 1 PX domain AAA_13 PF13166.6 EEQ36178.1 - 0.033 12.8 7.1 0.05 12.2 7.1 1.1 1 0 0 1 1 1 0 AAA domain Cortex-I_coil PF09304.10 EEQ36178.1 - 0.073 13.3 0.3 0.073 13.3 0.3 2.6 3 0 0 3 3 3 0 Cortexillin I, coiled coil DUF2417 PF10329.9 EEQ36179.1 - 1.2e-68 231.1 3.4 1.7e-68 230.5 3.4 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_1 PF00561.20 EEQ36179.1 - 3.6e-05 23.6 0.0 6.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FHA PF00498.26 EEQ36180.1 - 1.5e-13 50.9 0.0 2.7e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EEQ36180.1 - 2.5e-11 43.1 7.2 4.8e-11 42.2 7.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EEQ36180.1 - 5.3e-05 23.5 4.0 0.00012 22.4 4.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ36180.1 - 0.001 18.8 3.3 0.0022 17.8 3.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 EEQ36180.1 - 0.0024 18.2 0.0 0.0053 17.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 EEQ36180.1 - 0.012 15.5 4.1 0.012 15.5 4.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ36180.1 - 0.025 14.9 1.8 0.085 13.2 1.8 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ36180.1 - 0.14 12.2 4.5 0.31 11.1 4.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ36180.1 - 0.24 11.4 3.3 0.53 10.3 3.3 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DUF3292 PF11696.8 EEQ36180.1 - 0.34 9.2 3.4 0.47 8.8 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Sugar_tr PF00083.24 EEQ36181.1 - 3.7e-93 312.8 25.2 4.6e-93 312.5 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36181.1 - 7.2e-20 71.2 18.9 7.2e-20 71.2 18.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ36181.1 - 4.1e-07 28.9 20.7 0.0002 20.1 2.0 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 EEQ36181.1 - 0.00013 20.9 0.5 0.00013 20.9 0.5 2.7 3 1 0 3 3 3 1 MFS_1 like family MFS_4 PF06779.14 EEQ36181.1 - 0.00081 18.8 5.4 0.00081 18.8 5.4 2.3 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 EEQ36182.1 - 3.9e-08 32.7 0.8 3.9e-08 32.7 0.8 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ36182.1 - 0.00091 19.3 12.8 0.002 18.2 12.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 EEQ36183.1 - 1.6e-16 60.6 0.0 1.8e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ36183.1 - 1.3e-08 35.1 0.1 2.3e-08 34.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ36183.1 - 3.5e-07 30.2 0.0 4.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EEQ36183.1 - 0.00087 20.0 0.0 0.0014 19.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEQ36183.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase His_Phos_1 PF00300.22 EEQ36184.1 - 8.1e-39 133.3 0.0 1.3e-38 132.6 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Cation_ATPase_C PF00689.21 EEQ36185.1 - 3e-11 43.3 5.1 6.3e-11 42.3 5.1 1.5 1 1 0 1 1 1 1 Cation transporting ATPase, C-terminus SfLAP PF11139.8 EEQ36185.1 - 0.0097 15.4 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein E1-E2_ATPase PF00122.20 EEQ36186.1 - 1.2e-33 116.1 23.7 1.9e-29 102.5 0.5 3.0 3 0 0 3 3 3 2 E1-E2 ATPase Cation_ATPase PF13246.6 EEQ36186.1 - 4.6e-19 68.3 0.0 1e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEQ36186.1 - 1.8e-18 67.6 0.0 1.4e-17 64.7 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEQ36186.1 - 5.2e-14 51.7 0.0 1.2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ36186.1 - 0.009 15.8 0.4 0.47 10.2 0.2 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2208 PF09973.9 EEQ36186.1 - 0.095 12.3 2.0 6 6.4 0.7 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) NatB_MDM20 PF09797.9 EEQ36188.1 - 4.8e-43 147.5 16.4 9e-41 140.1 16.4 2.6 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EEQ36188.1 - 0.00022 21.6 2.7 33 5.1 0.3 5.0 3 2 2 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ36188.1 - 0.00086 19.5 4.4 0.0015 18.8 0.5 2.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EEQ36188.1 - 0.001 19.6 1.4 0.014 16.0 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36188.1 - 0.0016 19.1 1.9 0.65 11.0 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ36188.1 - 0.012 15.6 0.4 0.78 10.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ36188.1 - 0.06 14.0 1.0 4.1 8.1 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ36188.1 - 0.1 12.7 0.1 6.5 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Arteri_nsp7a PF16749.5 EEQ36188.1 - 0.13 12.4 0.1 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha ApoM PF11032.8 EEQ36189.1 - 0.019 14.7 0.5 0.054 13.2 0.1 1.8 2 0 0 2 2 2 0 ApoM domain LRR_4 PF12799.7 EEQ36190.1 - 0.0024 18.2 0.1 6.3 7.4 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EEQ36190.1 - 0.005 16.8 0.1 24 5.3 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat Arrestin_C PF02752.22 EEQ36191.1 - 2.8e-23 82.8 0.1 6.7e-21 75.1 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEQ36191.1 - 6.2e-12 45.8 0.5 8.5e-08 32.4 0.1 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EEQ36191.1 - 0.00019 21.2 0.0 0.00041 20.1 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like SNARE PF05739.19 EEQ36192.1 - 1.2e-12 47.6 1.8 2.2e-12 46.8 0.4 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EEQ36192.1 - 0.00062 19.5 11.8 0.0029 17.3 11.8 2.1 1 1 0 1 1 1 1 Syntaxin EVI2A PF05399.11 EEQ36192.1 - 0.008 15.8 1.1 0.015 14.9 0.3 2.0 2 1 0 2 2 2 1 Ectropic viral integration site 2A protein (EVI2A) THOC7 PF05615.13 EEQ36192.1 - 0.83 9.9 12.5 4.4 7.6 11.0 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 DUF2203 PF09969.9 EEQ36192.1 - 3.7 8.3 7.4 18 6.0 1.7 2.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SUR7 PF06687.12 EEQ36193.1 - 3.7e-14 52.9 20.0 8.8e-14 51.6 20.0 1.6 1 1 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 EEQ36193.1 - 0.00043 20.1 6.4 0.00043 20.1 6.4 1.6 2 0 0 2 2 2 1 Amastin surface glycoprotein PIP5K PF01504.18 EEQ36194.1 - 4.5e-43 147.4 5.5 1.6e-32 112.8 4.1 3.2 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EEQ36194.1 - 8.8e-25 87.3 0.1 1.7e-24 86.3 0.1 1.4 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EEQ36194.1 - 9.9e-17 60.8 11.1 1e-16 60.8 8.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger NOB1_Zn_bind PF08772.11 EEQ36194.1 - 1.5 9.1 11.7 2.5 8.3 0.0 3.3 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like C1_4 PF07975.12 EEQ36194.1 - 3.3 8.0 8.9 18 5.7 8.9 2.3 1 0 0 1 1 1 0 TFIIH C1-like domain GPP34 PF05719.11 EEQ36195.1 - 1e-66 224.8 0.0 1.4e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Glyco_hydro_18 PF00704.28 EEQ36196.1 - 9.3e-68 229.2 0.0 1.1e-67 229.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UCH PF00443.29 EEQ36197.1 - 1.6e-40 139.3 0.1 2.4e-40 138.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EEQ36197.1 - 7.5e-22 76.9 3.5 1.2e-18 66.6 0.1 2.7 2 0 0 2 2 2 2 Variant UBP zinc finger zf-UBP PF02148.19 EEQ36197.1 - 4.9e-20 71.6 15.9 4.9e-18 65.2 7.1 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EEQ36197.1 - 1e-15 57.3 5.4 2.3e-08 33.8 0.1 3.1 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 EEQ36197.1 - 1.7e-12 47.6 0.0 8.2e-12 45.3 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ZZ PF00569.17 EEQ36197.1 - 4.2 7.3 12.8 5.4 6.9 0.1 4.2 4 0 0 4 4 4 0 Zinc finger, ZZ type DAHP_synth_1 PF00793.20 EEQ36198.1 - 9.7e-80 267.4 0.0 1.1e-79 267.2 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family AA_permease_2 PF13520.6 EEQ36199.1 - 6e-51 173.6 56.4 7e-51 173.4 56.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ36199.1 - 1.7e-24 86.3 47.8 2.2e-24 85.9 47.8 1.0 1 0 0 1 1 1 1 Amino acid permease MatE PF01554.18 EEQ36200.1 - 3.9e-66 221.6 31.0 1.8e-40 138.2 8.7 2.3 2 0 0 2 2 2 2 MatE Glyco_hydro_76 PF03663.14 EEQ36201.1 - 2.6e-138 461.5 24.3 3.2e-138 461.2 24.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EEQ36201.1 - 0.0014 17.8 5.4 0.087 11.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 HAD_2 PF13419.6 EEQ36203.1 - 7.7e-13 48.9 0.0 3.3e-11 43.6 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ36203.1 - 9e-08 32.7 0.0 1.4e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ36203.1 - 1.4e-07 31.5 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans_2 PF11951.8 EEQ36204.1 - 1.1e-46 159.5 5.8 3e-34 118.5 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ36204.1 - 7.4e-07 29.2 10.7 1.3e-06 28.4 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adap_comp_sub PF00928.21 EEQ36205.1 - 3.1e-53 180.9 2.4 1.6e-52 178.5 2.4 2.2 1 1 0 1 1 1 1 Adaptor complexes medium subunit family BUD22 PF09073.10 EEQ36205.1 - 0.78 9.0 24.5 0.41 9.9 1.7 2.2 2 0 0 2 2 2 0 BUD22 GATase PF00117.28 EEQ36205.1 - 0.81 9.4 4.0 3.2 7.5 0.5 2.3 2 0 0 2 2 2 0 Glutamine amidotransferase class-I rRNA_processing PF08524.11 EEQ36205.1 - 9.5 6.2 25.8 6.6 6.8 12.9 2.5 2 0 0 2 2 2 0 rRNA processing Pterin_4a PF01329.19 EEQ36206.1 - 4.7e-22 78.0 2.3 7.9e-22 77.2 2.3 1.4 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Lactamase_B_2 PF12706.7 EEQ36206.1 - 0.011 15.2 0.2 0.017 14.6 0.2 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain HA2 PF04408.23 EEQ36208.1 - 3.8e-27 94.7 0.0 3.8e-27 94.7 0.0 4.3 4 1 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ36208.1 - 1e-11 45.1 0.0 8.8e-11 42.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EEQ36208.1 - 3.2e-11 43.4 0.0 9.6e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EEQ36208.1 - 1.3e-08 34.8 0.0 4.8e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ36208.1 - 2.4e-06 27.8 5.2 4.7e-06 26.9 0.1 3.5 3 1 0 3 3 3 1 AAA domain TsaE PF02367.17 EEQ36208.1 - 0.014 15.4 0.0 0.052 13.6 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EEQ36208.1 - 0.018 15.4 0.0 0.055 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EEQ36208.1 - 0.02 14.0 0.0 0.052 12.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EEQ36208.1 - 0.064 13.2 0.1 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Flavivirus DEAD domain G0-G1_switch_2 PF15103.6 EEQ36208.1 - 0.2 12.1 0.0 0.2 12.1 0.0 4.9 4 1 0 4 4 4 0 G0/G1 switch protein 2 Synaptobrevin PF00957.21 EEQ36209.1 - 1.6e-26 91.9 0.2 3.9e-26 90.7 0.0 1.7 2 0 0 2 2 2 1 Synaptobrevin Histone PF00125.24 EEQ36210.1 - 9.3e-07 29.3 0.1 9.3e-07 29.3 0.1 2.1 2 1 1 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEQ36210.1 - 1.2e-06 28.7 0.9 1.9e-06 28.1 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 EEQ36210.1 - 1.7e-06 28.1 1.0 4.5e-06 26.8 0.7 1.9 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EEQ36210.1 - 0.08 13.5 0.1 0.08 13.5 0.1 2.4 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A CDC45 PF02724.14 EEQ36210.1 - 2 6.6 10.2 2.5 6.3 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EEQ36210.1 - 7.9 5.7 14.4 12 5.2 14.4 1.2 1 0 0 1 1 1 0 NOA36 protein MOZ_SAS PF01853.18 EEQ36211.1 - 6.5e-46 156.2 0.0 9e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EEQ36211.1 - 1.9e-10 40.2 6.1 2e-05 24.1 3.9 2.7 2 0 0 2 2 2 2 MYST family zinc finger domain SNF2_N PF00176.23 EEQ36212.1 - 1.9e-70 237.3 0.9 4e-70 236.3 0.1 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.11 EEQ36212.1 - 3.6e-13 49.3 0.0 7.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4 PF00097.25 EEQ36212.1 - 2.5e-07 30.4 9.4 4.9e-07 29.5 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EEQ36212.1 - 1.6e-06 28.3 0.4 6.7e-06 26.2 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EEQ36212.1 - 1.8e-06 28.2 8.4 3.6e-06 27.2 8.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEQ36212.1 - 6.2e-06 26.0 5.9 1.1e-05 25.2 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ36212.1 - 0.00057 19.8 9.3 0.0011 18.9 9.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EEQ36212.1 - 0.0039 17.2 1.9 0.008 16.2 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EEQ36212.1 - 0.024 14.5 8.1 0.048 13.5 8.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ36212.1 - 0.029 14.7 5.7 0.062 13.6 5.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EEQ36212.1 - 0.057 13.6 8.9 0.14 12.4 8.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EEQ36212.1 - 0.082 13.0 7.3 0.18 11.9 7.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 EEQ36212.1 - 0.13 12.1 5.2 0.26 11.1 5.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EEQ36212.1 - 0.3 10.9 7.1 0.75 9.6 7.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger Helicase_C PF00271.31 EEQ36213.1 - 1.6e-16 60.6 0.0 2.6e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Imm5 PF14423.6 EEQ36213.1 - 0.06 13.6 0.1 0.095 12.9 0.1 1.4 1 1 0 1 1 1 0 Immunity protein Imm5 nos_propeller PF18764.1 EEQ36214.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Nitrous oxide reductase propeller repeat Nramp PF01566.18 EEQ36215.1 - 7.4e-88 294.9 26.9 9.6e-52 176.1 7.2 2.3 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein Nfu_N PF08712.11 EEQ36217.1 - 4.6e-27 93.9 0.3 1.4e-26 92.3 0.2 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EEQ36217.1 - 4e-26 91.0 0.1 6.4e-26 90.3 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain RhoGAP PF00620.27 EEQ36217.1 - 0.031 14.1 0.1 0.072 12.9 0.0 1.7 2 0 0 2 2 2 0 RhoGAP domain YojJ PF10372.9 EEQ36217.1 - 0.15 12.2 0.5 0.29 11.3 0.5 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus PHO4 PF01384.20 EEQ36218.1 - 9.4e-115 383.2 17.5 1.1e-114 383.0 17.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family F_actin_cap_B PF01115.17 EEQ36219.1 - 3.6e-92 308.3 0.0 4.2e-92 308.1 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Clathrin_lg_ch PF01086.17 EEQ36222.1 - 6.4e-56 190.0 19.6 7.5e-56 189.8 19.6 1.1 1 0 0 1 1 1 1 Clathrin light chain DUF4972 PF16342.5 EEQ36222.1 - 0.098 12.3 3.7 0.17 11.6 3.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4972) Hid1 PF12722.7 EEQ36222.1 - 4.3 5.4 5.1 4.4 5.3 5.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.32 EEQ36223.1 - 2.2e-33 113.7 18.7 0.00019 22.1 0.0 10.8 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36223.1 - 3.6e-13 49.6 4.1 0.019 15.3 0.0 7.8 5 1 4 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EEQ36223.1 - 0.0039 17.2 4.5 8.6 6.5 0.1 5.3 5 2 1 6 6 6 2 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EEQ36223.1 - 0.0055 15.7 5.2 0.025 13.6 1.8 3.4 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EEQ36223.1 - 0.015 15.2 0.4 2.7 8.1 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EEQ36223.1 - 0.024 13.2 0.0 0.099 11.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain MbtH PF03621.13 EEQ36223.1 - 0.038 13.4 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 MbtH-like protein nos_propeller PF18764.1 EEQ36223.1 - 0.05 13.5 0.0 1.2 9.1 0.0 2.5 1 1 1 2 2 2 0 Nitrous oxide reductase propeller repeat DEAD PF00270.29 EEQ36224.1 - 1e-46 158.9 0.2 3.4e-46 157.2 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ36224.1 - 2.9e-22 79.1 0.0 1.9e-21 76.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEQ36224.1 - 9.3e-19 67.4 0.0 2.7e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEQ36224.1 - 3.3e-06 27.2 0.0 3.3e-06 27.2 0.0 2.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EEQ36224.1 - 0.027 14.7 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 Helicase C-terminal domain RNA_pol_Rpc4 PF05132.14 EEQ36225.1 - 4.9e-17 62.7 7.2 4.9e-17 62.7 7.2 3.2 2 1 0 2 2 2 1 RNA polymerase III RPC4 Sas10 PF09368.10 EEQ36226.1 - 7.7e-27 93.6 11.2 7.7e-27 93.6 11.2 2.5 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EEQ36226.1 - 1.7e-05 25.3 0.1 1.7e-05 25.3 0.1 3.7 3 2 0 3 3 3 1 Sas10/Utp3/C1D family Cpn60_TCP1 PF00118.24 EEQ36227.1 - 9.8e-148 492.8 14.2 1.1e-147 492.6 14.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AbrB_C PF18277.1 EEQ36227.1 - 0.057 13.1 0.1 0.32 10.7 0.1 2.3 1 1 1 2 2 2 0 AbrB C-terminal domain D123 PF07065.14 EEQ36228.1 - 1.2e-93 313.6 8.0 1.4e-93 313.4 8.0 1.0 1 0 0 1 1 1 1 D123 R2K_3 PF14243.6 EEQ36228.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 AA_permease PF00324.21 EEQ36229.1 - 1.5e-147 492.1 41.0 1.7e-147 491.9 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ36229.1 - 2.7e-40 138.5 43.8 3.3e-40 138.2 43.8 1.0 1 0 0 1 1 1 1 Amino acid permease OppC_N PF12911.7 EEQ36229.1 - 3.2 7.8 7.2 14 5.8 0.0 4.2 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C SGL PF08450.12 EEQ36230.1 - 5.9e-39 134.1 0.1 7e-39 133.9 0.1 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EEQ36230.1 - 0.00026 21.0 0.0 0.00074 19.6 0.0 1.8 2 0 0 2 2 2 1 Strictosidine synthase DPPIV_N PF00930.21 EEQ36230.1 - 0.06 12.1 0.0 0.51 9.1 0.0 1.9 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region zf-HIT PF04438.16 EEQ36231.1 - 2.7e-10 39.9 11.2 4.7e-10 39.2 11.2 1.4 1 0 0 1 1 1 1 HIT zinc finger Hit1_C PF18268.1 EEQ36231.1 - 6.8e-06 26.1 0.0 1.2e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Hit1 C-terminal zf-MYND PF01753.18 EEQ36231.1 - 0.0055 16.8 7.8 0.0081 16.2 7.8 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EEQ36231.1 - 0.069 13.5 6.8 0.13 12.6 6.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding YL1_C PF08265.11 EEQ36231.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Cyclin_N PF00134.23 EEQ36233.1 - 5.7e-05 22.9 0.9 7.4e-05 22.5 0.9 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EEQ36233.1 - 0.00067 20.1 0.1 0.00095 19.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin Fungal_trans PF04082.18 EEQ36234.1 - 9.5e-15 54.3 0.0 1.6e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ36234.1 - 9.8e-08 32.0 8.4 1.8e-07 31.1 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EEQ36235.1 - 2.6e-09 37.0 15.4 7.7e-05 22.9 2.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ36235.1 - 1.7e-08 34.5 15.3 6e-05 23.3 4.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ36235.1 - 3.6e-05 24.2 11.7 0.014 16.1 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EEQ36235.1 - 0.019 14.9 1.2 2.4 8.3 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger FOXP-CC PF16159.5 EEQ36235.1 - 0.081 13.6 0.1 0.081 13.6 0.1 1.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EEQ36235.1 - 0.09 13.1 2.1 0.24 11.7 0.8 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EEQ36235.1 - 0.54 10.1 12.6 0.65 9.8 0.3 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Cyclin_N PF00134.23 EEQ36238.1 - 7e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EEQ36238.1 - 0.054 13.9 0.0 0.093 13.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin CHZ PF09649.10 EEQ36241.1 - 2e-18 65.5 1.6 2e-18 65.5 1.6 2.9 3 0 0 3 3 3 1 Histone chaperone domain CHZ DUF908 PF06012.12 EEQ36241.1 - 3.2 7.1 5.9 3.8 6.8 5.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PPL5 PF18168.1 EEQ36241.1 - 4.2 6.6 7.6 4.5 6.5 6.9 1.4 1 1 0 1 1 1 0 Prim-pol family 5 LSM PF01423.22 EEQ36242.1 - 3.3e-18 65.1 0.1 4.7e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EEQ36242.1 - 0.032 14.4 0.1 0.16 12.1 0.0 2.1 1 1 1 2 2 2 0 RimP C-terminal SH3 domain Ras PF00071.22 EEQ36243.1 - 1.3e-59 200.5 0.1 1.5e-59 200.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ36243.1 - 1.9e-34 118.5 0.0 3.1e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ36243.1 - 2.3e-12 46.7 0.0 2.9e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEQ36243.1 - 3.4e-07 30.3 0.0 6.6e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ36243.1 - 0.0017 18.3 0.5 0.029 14.3 0.1 2.1 1 1 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EEQ36243.1 - 0.0035 16.9 0.0 0.0095 15.5 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain KAP_NTPase PF07693.14 EEQ36243.1 - 0.0059 15.9 0.0 0.0089 15.3 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 EEQ36243.1 - 0.008 16.5 0.1 0.065 13.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ36243.1 - 0.0082 16.5 0.1 0.016 15.6 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 EEQ36243.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ABC_tran PF00005.27 EEQ36243.1 - 0.015 15.8 0.0 0.021 15.3 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EEQ36243.1 - 0.02 14.6 0.0 0.053 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 EEQ36243.1 - 0.044 13.2 0.0 0.071 12.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EEQ36243.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EEQ36243.1 - 0.089 12.7 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.18 EEQ36243.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EEQ36243.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein SPT16 PF08644.11 EEQ36244.1 - 1.7e-49 167.9 0.1 1.7e-49 167.9 0.1 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EEQ36244.1 - 6.5e-47 159.3 3.1 3.5e-46 156.9 0.8 3.1 2 1 1 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EEQ36244.1 - 3.5e-24 85.7 0.0 6.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EEQ36244.1 - 1.7e-14 53.9 0.8 4.4e-14 52.7 0.1 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DNA_primase_lrg PF04104.14 EEQ36245.1 - 3e-81 272.8 0.0 3.8e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit YugN PF08868.10 EEQ36245.1 - 0.074 13.0 0.1 1.5 8.7 0.0 2.5 3 0 0 3 3 3 0 YugN-like family BTAD PF03704.17 EEQ36245.1 - 1.6 9.2 6.8 3.3 8.1 3.6 2.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain PEX11 PF05648.14 EEQ36246.1 - 0.00092 18.7 6.7 0.16 11.4 0.3 3.2 2 1 1 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) ApbA_C PF08546.11 EEQ36247.1 - 1e-28 100.0 0.0 2.3e-28 98.9 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EEQ36247.1 - 6.9e-26 90.7 0.1 3.2e-25 88.5 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EEQ36247.1 - 0.0011 19.4 0.4 0.0024 18.4 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EEQ36247.1 - 0.0053 16.4 0.2 0.0091 15.6 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EEQ36247.1 - 0.022 13.6 0.3 0.031 13.1 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.6 EEQ36247.1 - 0.027 14.9 0.3 0.17 12.3 0.1 2.3 3 1 0 3 3 3 0 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EEQ36247.1 - 0.068 12.2 0.8 0.11 11.6 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 EEQ36247.1 - 0.073 12.3 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EEQ36247.1 - 0.093 11.9 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GARS_N PF02844.15 EEQ36247.1 - 0.1 13.4 0.1 0.44 11.4 0.0 2.0 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain DUF4536 PF15055.6 EEQ36247.1 - 0.39 11.0 2.8 11 6.4 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) Lysine_decarbox PF03641.14 EEQ36248.1 - 2.3e-41 141.0 0.1 2.8e-41 140.7 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EEQ36248.1 - 1.3e-16 60.6 0.8 3.2e-16 59.3 0.8 1.7 1 1 0 1 1 1 1 SLOG cluster4 family Pro_CA PF00484.19 EEQ36249.1 - 1.2e-42 145.8 0.0 1.7e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase SNF2_N PF00176.23 EEQ36250.1 - 5.3e-64 216.1 0.2 1.1e-63 215.0 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ36250.1 - 7.3e-21 74.6 0.0 3.4e-20 72.5 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ36250.1 - 8.7e-11 42.1 0.0 8.7e-11 42.1 0.0 3.4 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ36250.1 - 3.8e-05 23.5 0.0 8.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4587 PF15248.6 EEQ36250.1 - 0.0076 17.0 0.1 0.058 14.2 0.1 2.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4587) Glyco_hydro_15 PF00723.21 EEQ36251.1 - 2.4e-56 191.4 0.0 3.2e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 MMgT PF10270.9 EEQ36252.1 - 3.4e-22 78.7 0.0 4.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter FA_hydroxylase PF04116.13 EEQ36254.1 - 4.3e-22 78.9 23.5 4.3e-22 78.9 23.5 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 EEQ36255.1 - 4.6e-40 137.6 30.7 4.6e-40 137.6 30.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short_C2 PF13561.6 EEQ36257.1 - 1.1e-50 172.5 0.2 2.1e-50 171.5 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ36257.1 - 7.8e-35 120.1 0.2 1.7e-34 119.0 0.2 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ36257.1 - 7.5e-05 22.7 0.1 0.00011 22.2 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EEQ36257.1 - 0.16 11.9 0.2 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gtr1_RagA PF04670.12 EEQ36259.1 - 4e-68 229.2 0.2 5.3e-68 228.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EEQ36259.1 - 0.0066 15.9 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.6 EEQ36259.1 - 0.035 14.1 0.0 0.072 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DIE2_ALG10 PF04922.12 EEQ36261.1 - 1.1e-104 350.9 24.6 3.8e-104 349.1 24.6 1.8 1 1 0 1 1 1 1 DIE2/ALG10 family ECSCR PF15820.5 EEQ36261.1 - 3.5 7.5 4.1 2.3 8.1 1.2 2.0 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator SMI1_KNR4 PF09346.10 EEQ36262.1 - 4.6e-36 124.1 0.0 2.1e-35 122.0 0.0 2.2 1 1 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 EEQ36262.1 - 0.075 13.5 0.5 6.9 7.1 0.1 3.4 2 1 0 2 2 2 0 SMI1-KNR4 cell-wall PTH2 PF01981.16 EEQ36265.1 - 3.1e-43 146.8 0.1 4.1e-43 146.4 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Myb_DNA-bind_6 PF13921.6 EEQ36266.1 - 1.2e-10 41.4 2.2 1.2e-09 38.3 0.1 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EEQ36266.1 - 2.9e-09 37.0 2.4 3.2e-07 30.4 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 EEQ36266.1 - 0.056 13.3 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Chorismate_bind PF00425.18 EEQ36267.1 - 5.3e-90 301.5 0.0 7.4e-90 301.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EEQ36267.1 - 1.3e-30 106.4 0.0 3.9e-28 98.4 0.0 3.1 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region POR PF01558.18 EEQ36267.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase DUF2312 PF10073.9 EEQ36267.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) RNB PF00773.19 EEQ36268.1 - 4e-05 23.1 0.0 0.11 11.7 0.0 2.4 2 0 0 2 2 2 2 RNB domain APC_r PF05923.12 EEQ36268.1 - 0.076 12.8 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 APC repeat AAA_12 PF13087.6 EEQ36269.1 - 8.9e-59 198.5 0.0 2.5e-58 197.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ36269.1 - 1.4e-36 126.6 0.4 6.9e-19 68.7 0.1 4.4 2 2 1 3 3 2 2 AAA domain AAA_19 PF13245.6 EEQ36269.1 - 6.3e-12 46.0 0.1 2.3e-11 44.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EEQ36269.1 - 1.4e-09 38.0 0.0 1.8e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EEQ36269.1 - 5.6e-06 26.5 0.0 2.6e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EEQ36269.1 - 1.5e-05 24.8 0.0 0.054 13.2 0.0 3.8 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EEQ36269.1 - 0.00039 20.0 0.0 0.00039 20.0 0.0 3.4 3 1 0 3 3 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.16 EEQ36269.1 - 0.0011 18.5 0.0 0.027 13.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 EEQ36269.1 - 0.0042 17.5 0.0 0.024 15.0 0.0 2.3 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 EEQ36269.1 - 0.0087 15.8 0.1 0.062 13.1 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase ATPase_2 PF01637.18 EEQ36269.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EEQ36269.1 - 0.04 14.2 0.0 0.29 11.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_7 PF12775.7 EEQ36269.1 - 0.044 13.3 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region UPF1_Zn_bind PF09416.10 EEQ36269.1 - 0.061 13.3 0.2 0.061 13.3 0.2 2.5 2 1 1 3 3 3 0 RNA helicase (UPF2 interacting domain) RNA_helicase PF00910.22 EEQ36269.1 - 0.085 13.2 0.7 0.82 10.1 0.0 3.1 4 0 0 4 4 2 0 RNA helicase AAA_26 PF13500.6 EEQ36269.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ36269.1 - 0.21 12.0 0.0 0.41 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain zf-UBR PF02207.20 EEQ36269.1 - 1.4 9.1 12.4 20 5.4 4.8 3.3 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Cytochrome_C7 PF14522.6 EEQ36269.1 - 1.4 9.0 7.6 0.9 9.6 0.4 2.8 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c CEBP_ZZ PF16366.5 EEQ36269.1 - 1.7 8.9 8.5 1.5 9.1 1.5 3.1 3 0 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-DNL PF05180.12 EEQ36269.1 - 7.2 6.6 8.3 2.1 8.4 0.5 2.8 2 0 0 2 2 2 0 DNL zinc finger ArfGap PF01412.18 EEQ36269.1 - 7.8 6.6 7.6 7.7 6.6 2.1 3.2 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf SEP PF08059.13 EEQ36270.1 - 3.5e-22 78.7 0.0 8.7e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EEQ36270.1 - 1.2e-17 63.8 0.0 2.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EEQ36270.1 - 8.4e-09 35.1 0.9 1.4e-08 34.4 0.9 1.3 1 0 0 1 1 1 1 UBA-like domain Meth_synt_2 PF01717.18 EEQ36272.1 - 2.8e-150 500.1 0.0 1.3e-146 488.0 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EEQ36272.1 - 2.6e-116 388.5 0.1 7.4e-110 367.3 0.1 2.8 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Gsf2 PF11055.8 EEQ36273.1 - 3.6e-143 476.8 0.0 4.2e-143 476.6 0.0 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 Glyco_hydro_72 PF03198.14 EEQ36274.1 - 2.7e-109 365.3 0.9 3.4e-109 364.9 0.9 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EEQ36274.1 - 0.0049 16.3 0.1 0.0099 15.3 0.1 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EEQ36274.1 - 0.0081 15.3 0.1 0.021 14.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain X8 PF07983.13 EEQ36276.1 - 1.8e-27 95.8 4.6 4e-27 94.7 4.6 1.6 1 0 0 1 1 1 1 X8 domain Glyco_hydro_72 PF03198.14 EEQ36276.1 - 7.4e-16 58.3 0.2 7.4e-16 58.3 0.2 1.6 2 0 0 2 2 2 1 Glucanosyltransferase Glucan_synthase PF02364.15 EEQ36278.1 - 3.7e-35 121.3 0.1 3.7e-35 121.3 0.1 1.4 2 0 0 2 2 2 1 1,3-beta-glucan synthase component Glucan_synthase PF02364.15 EEQ36279.1 - 3e-221 736.9 0.3 3.8e-221 736.5 0.3 1.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EEQ36280.1 - 2.2e-33 115.3 3.0 6.8e-32 110.5 3.0 2.5 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glucan_synthase PF02364.15 EEQ36280.1 - 3.7e-31 108.1 0.2 7.4e-31 107.1 0.2 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component NDT80_PhoG PF05224.12 EEQ36281.1 - 2e-43 148.8 0.0 5.5e-43 147.4 0.0 1.7 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF1336 PF07059.12 EEQ36281.1 - 0.2 11.7 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) Mito_carr PF00153.27 EEQ36282.1 - 5.7e-57 189.7 1.6 2.9e-20 72.0 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ36282.1 - 0.014 14.5 0.0 0.72 8.9 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease DUF1279 PF06916.13 EEQ36284.1 - 5.9e-28 97.3 0.0 1e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Bac_small_YrzI PF09501.10 EEQ36284.1 - 0.065 13.4 1.1 0.11 12.6 1.1 1.4 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) ThiF PF00899.21 EEQ36285.1 - 6.9e-45 153.3 0.3 1.3e-44 152.4 0.0 1.5 2 0 0 2 2 2 1 ThiF family Sacchrp_dh_NADP PF03435.18 EEQ36285.1 - 0.00019 21.7 1.8 0.0039 17.5 1.8 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF3824 PF12868.7 EEQ36285.1 - 0.033 14.8 0.5 0.069 13.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Retinin_C PF04527.12 EEQ36286.1 - 0.12 12.6 0.3 0.27 11.5 0.2 1.7 1 1 1 2 2 2 0 Drosophila Retinin like protein Methyltransf_PK PF05891.12 EEQ36287.1 - 3.3e-79 265.4 0.0 3.8e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EEQ36287.1 - 8.6e-05 23.2 0.0 0.00032 21.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 EEQ36287.1 - 0.053 12.8 0.1 0.23 10.7 0.0 2.1 2 1 0 2 2 2 0 O-methyltransferase domain Sld5 PF05916.11 EEQ36288.1 - 4.6e-21 75.3 0.0 6e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein TPR_2 PF07719.17 EEQ36289.1 - 1e-26 90.8 25.4 0.00065 19.6 0.1 14.4 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ36289.1 - 5.8e-23 79.7 17.1 0.0036 17.1 0.0 13.3 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36289.1 - 7.3e-19 66.8 11.9 0.67 10.9 0.0 13.8 12 3 4 16 16 13 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ36289.1 - 2.9e-18 64.5 32.4 0.0074 16.4 0.0 15.3 17 1 1 18 18 16 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ36289.1 - 4.9e-15 55.8 29.0 4.9e-05 23.8 0.0 11.0 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ36289.1 - 1.7e-14 54.1 19.0 0.00033 21.2 0.0 8.4 7 3 2 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ36289.1 - 2.6e-14 53.3 22.2 0.00099 19.4 0.0 11.3 9 4 4 14 14 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ36289.1 - 7.9e-13 48.1 15.1 1.8 9.4 0.0 12.1 11 1 0 11 11 11 2 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ36289.1 - 1.6e-12 46.9 11.4 1.6 8.5 0.0 10.2 9 1 1 10 10 10 5 TPR repeat ANAPC3 PF12895.7 EEQ36289.1 - 1.2e-10 41.5 11.7 4.5e-05 23.6 0.1 6.4 6 0 0 6 6 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EEQ36289.1 - 1.7e-09 37.4 8.0 0.071 13.5 0.0 9.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ36289.1 - 4.2e-07 29.5 9.6 0.19 11.8 0.0 8.7 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ36289.1 - 1.6e-05 24.6 5.0 20 5.2 0.0 8.7 10 0 0 10 10 10 0 Tetratricopeptide repeat DUF2225 PF09986.9 EEQ36289.1 - 3.1 7.5 19.9 1.2 8.8 0.1 5.1 5 1 0 5 5 5 0 Uncharacterized protein conserved in bacteria (DUF2225) FIVAR PF07554.13 EEQ36289.1 - 4.9 8.0 15.2 0.59 10.9 0.5 5.0 4 0 0 4 4 4 0 FIVAR domain DASH_Dad4 PF08650.10 EEQ36289.1 - 6 6.9 9.0 8.2 6.5 0.3 3.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 Herpes_UL49_1 PF03117.14 EEQ36290.1 - 0.072 12.4 0.3 0.11 11.8 0.3 1.2 1 0 0 1 1 1 0 UL49 family RVT_2 PF07727.14 EEQ36291.1 - 7.5e-77 258.2 0.3 1e-76 257.8 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EEQ36291.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RSB_motif PF16294.5 EEQ36291.1 - 0.18 12.1 1.5 0.6 10.4 0.1 2.2 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif eRF1_2 PF03464.15 EEQ36292.1 - 5.1e-46 156.3 0.1 9.2e-46 155.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EEQ36292.1 - 1.7e-36 125.1 0.3 3.6e-36 124.1 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EEQ36292.1 - 8.4e-20 71.1 0.0 1.6e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EEQ36292.1 - 2e-11 44.3 0.0 3.2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EEQ36292.1 - 7.5e-10 39.2 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor Tnp_DNA_bind PF14706.6 EEQ36292.1 - 0.033 14.0 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Transposase DNA-binding Ribosomal_L7Ae PF01248.26 EEQ36292.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3440 PF11922.8 EEQ36292.1 - 0.089 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) DEAD PF00270.29 EEQ36293.1 - 3.3e-38 131.2 0.0 8.5e-38 129.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ36293.1 - 4.7e-27 94.5 0.0 2.2e-26 92.4 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EEQ36293.1 - 0.13 12.6 3.5 0.19 12.0 1.0 2.6 2 1 0 2 2 2 0 AAA domain Arg_decarbox_C PF17944.1 EEQ36293.1 - 0.89 10.2 3.0 2 9.1 1.5 2.4 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension MFS_1 PF07690.16 EEQ36294.1 - 4.5e-33 114.6 22.2 6.5e-32 110.8 23.2 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily RseC_MucC PF04246.12 EEQ36294.1 - 0.027 14.4 6.2 0.033 14.1 0.0 3.4 3 1 2 5 5 5 0 Positive regulator of sigma(E), RseC/MucC ESSS PF10183.9 EEQ36294.1 - 0.16 12.2 0.1 0.63 10.3 0.0 2.0 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Bmt2 PF11968.8 EEQ36295.1 - 5.2e-87 291.3 0.0 6.8e-87 290.9 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 EEQ36295.1 - 1e-07 31.9 0.0 3.4e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ36295.1 - 0.0016 19.2 0.0 0.0079 16.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ36295.1 - 0.0016 19.0 0.0 0.0081 16.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ36295.1 - 0.002 18.8 0.2 0.016 15.9 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ36295.1 - 0.045 13.6 0.0 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.24 EEQ36296.1 - 1.9e-157 524.8 29.6 2.2e-157 524.6 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36296.1 - 2.4e-29 102.4 24.8 6e-26 91.2 12.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PAP_assoc PF03828.19 EEQ36296.1 - 0.097 12.9 0.3 1.6 9.0 0.1 2.6 2 0 0 2 2 2 0 Cid1 family poly A polymerase Sugar_tr PF00083.24 EEQ36297.1 - 2.3e-87 293.8 4.0 3.5e-87 293.1 4.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36297.1 - 7.5e-13 48.1 3.3 1.4e-12 47.2 3.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily YqhR PF11085.8 EEQ36297.1 - 0.12 12.3 0.3 0.12 12.3 0.3 2.5 3 0 0 3 3 3 0 Conserved membrane protein YqhR TMEM107 PF14995.6 EEQ36297.1 - 0.32 11.4 2.4 0.8 10.2 0.0 2.5 2 1 1 3 3 3 0 Transmembrane protein EMP70 PF02990.16 EEQ36297.1 - 0.39 9.3 6.0 0.087 11.5 2.8 1.4 2 0 0 2 2 2 0 Endomembrane protein 70 Sugar_tr PF00083.24 EEQ36298.1 - 4.9e-128 427.8 28.5 5.5e-128 427.6 28.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36298.1 - 1.9e-17 63.2 27.4 5.7e-14 51.8 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 EEQ36298.1 - 0.14 11.7 7.3 0.15 11.6 2.9 2.7 2 2 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4293 PF14126.6 EEQ36298.1 - 0.42 10.9 14.2 1.9 8.7 3.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Aminotran_1_2 PF00155.21 EEQ36299.1 - 4.2e-81 272.9 0.0 4.8e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4250 PF14056.6 EEQ36299.1 - 0.016 15.1 0.1 0.043 13.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) PGM_PMM_I PF02878.16 EEQ36300.1 - 3.1e-37 127.4 0.2 5e-37 126.7 0.2 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EEQ36300.1 - 5.9e-25 87.7 0.0 1.6e-24 86.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EEQ36300.1 - 3.5e-14 53.3 0.0 8.6e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EEQ36300.1 - 7.2e-07 29.3 0.0 1.8e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GATA PF00320.27 EEQ36301.1 - 9.3e-15 53.9 4.5 2.1e-14 52.8 4.5 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EEQ36301.1 - 0.0029 17.1 0.5 0.0054 16.2 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Pox_A_type_inc PF04508.12 EEQ36301.1 - 0.0034 17.2 1.2 0.92 9.5 0.2 2.5 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Auto_anti-p27 PF06677.12 EEQ36301.1 - 0.35 11.1 1.1 0.61 10.3 1.1 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) dsRBD2 PF17842.1 EEQ36303.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 PseudoU_synth_2 PF00849.22 EEQ36304.1 - 5.3e-25 88.4 0.0 8.2e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ribosomal_S15 PF00312.22 EEQ36305.1 - 5.9e-26 90.5 0.1 5.9e-26 90.5 0.1 1.9 3 0 0 3 3 3 1 Ribosomal protein S15 Nnf1 PF03980.14 EEQ36306.1 - 3e-24 85.5 5.1 7.3e-24 84.3 5.1 1.6 1 0 0 1 1 1 1 Nnf1 bZIP_1 PF00170.21 EEQ36306.1 - 0.0028 17.7 1.9 0.023 14.8 1.2 2.7 3 0 0 3 3 3 1 bZIP transcription factor DUF4559 PF15112.6 EEQ36306.1 - 0.041 13.5 7.8 0.066 12.9 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) ZapB PF06005.12 EEQ36306.1 - 0.29 11.6 6.1 0.16 12.4 1.4 2.8 3 1 0 3 3 3 0 Cell division protein ZapB HALZ PF02183.18 EEQ36306.1 - 4.1 7.7 9.7 0.57 10.4 2.2 3.2 4 1 0 4 4 4 0 Homeobox associated leucine zipper SNAP PF14938.6 EEQ36307.1 - 1.6e-109 365.7 7.4 1.8e-109 365.5 7.4 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 EEQ36307.1 - 0.00011 22.2 3.8 0.013 15.7 0.1 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ36307.1 - 0.00022 21.1 6.3 0.51 10.6 0.1 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ36307.1 - 0.00047 20.4 6.5 0.3 11.4 1.3 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat NSF PF02071.20 EEQ36307.1 - 0.0015 18.8 6.9 13 7.1 0.0 6.0 5 0 0 5 5 5 0 Aromatic-di-Alanine (AdAR) repeat RPN7 PF10602.9 EEQ36307.1 - 0.0033 17.1 0.2 0.012 15.3 0.1 2.0 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_14 PF13428.6 EEQ36307.1 - 0.004 17.9 1.8 8.1 7.6 0.0 4.2 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ36307.1 - 0.0069 17.0 0.7 7.9 7.4 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ36307.1 - 0.0077 16.2 1.3 0.31 11.2 0.1 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ36307.1 - 0.0093 16.5 2.4 0.23 12.0 0.3 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ36307.1 - 0.012 15.0 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 MalT-like TPR region Mad3_BUB1_I PF08311.12 EEQ36307.1 - 0.019 15.0 0.5 0.39 10.7 0.1 2.8 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_16 PF13432.6 EEQ36307.1 - 0.026 15.2 3.6 1.8 9.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EEQ36307.1 - 0.055 13.5 7.8 0.69 10.0 0.3 4.1 2 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain DUF2225 PF09986.9 EEQ36307.1 - 0.12 12.1 2.9 1.2 8.8 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.6 EEQ36307.1 - 0.24 11.3 2.4 31 4.6 0.1 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ36307.1 - 0.37 10.7 7.9 4.1 7.4 0.1 4.6 4 2 0 4 4 4 0 Tetratricopeptide repeat CPSase_L_D2 PF02786.17 EEQ36308.1 - 1.5e-109 364.4 0.0 7.8e-84 280.4 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EEQ36308.1 - 1.6e-40 138.2 0.2 4e-40 137.0 0.2 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 EEQ36308.1 - 7.5e-21 74.5 0.1 1.7e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EEQ36308.1 - 1.8e-17 63.5 0.5 9.7e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EEQ36308.1 - 4e-11 42.8 0.0 0.00013 21.7 0.0 2.6 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EEQ36308.1 - 1.5e-05 24.5 0.1 0.086 12.3 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 EEQ36308.1 - 0.0012 18.5 0.0 0.89 9.1 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 EEQ36308.1 - 0.0034 17.2 0.1 1.7 8.4 0.0 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain PIG-P PF08510.12 EEQ36309.1 - 6.1e-37 126.2 4.7 6.1e-37 126.2 4.7 1.4 2 0 0 2 2 2 1 PIG-P DPM2 PF07297.12 EEQ36309.1 - 1.9 8.8 10.4 0.55 10.6 7.2 1.7 2 0 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) HEAT PF02985.22 EEQ36310.1 - 4.6e-22 76.2 24.1 0.00019 21.4 0.0 12.1 13 0 0 13 13 13 5 HEAT repeat HEAT_EZ PF13513.6 EEQ36310.1 - 1.7e-21 76.3 14.5 3.6e-10 40.1 0.1 8.7 8 1 1 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 EEQ36310.1 - 8.6e-20 70.9 10.9 0.00059 20.2 0.1 9.2 5 2 3 9 9 9 5 HEAT repeats Vac14_Fab1_bd PF12755.7 EEQ36310.1 - 3e-12 46.9 0.0 0.023 15.3 0.0 4.8 4 1 0 4 4 3 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EEQ36310.1 - 8.7e-09 35.6 0.0 0.00024 21.2 0.0 4.9 3 2 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EEQ36310.1 - 1.7e-08 34.2 0.5 0.03 14.2 0.0 4.0 2 1 1 3 3 3 2 Importin-beta N-terminal domain TAF6_C PF07571.13 EEQ36310.1 - 0.00017 21.9 0.1 0.29 11.5 0.1 3.3 2 1 0 2 2 2 2 TAF6 C-terminal HEAT repeat domain UME PF08064.13 EEQ36310.1 - 0.0002 21.2 0.7 3.6 7.6 0.0 4.8 4 1 0 4 4 4 1 UME (NUC010) domain Adaptin_N PF01602.20 EEQ36310.1 - 0.00025 19.7 0.1 0.054 12.0 0.0 3.6 2 2 0 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.8 EEQ36310.1 - 0.00042 20.0 1.2 2.6 7.6 0.0 4.9 4 2 0 5 5 5 1 CLASP N terminal Arm PF00514.23 EEQ36310.1 - 0.00045 20.2 8.2 1.7 8.8 0.0 6.4 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EEQ36310.1 - 0.0012 19.0 0.1 0.21 11.8 0.0 4.0 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 EEQ36310.1 - 0.021 14.6 0.1 14 5.3 0.1 4.5 3 1 1 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.16 EEQ36310.1 - 2.1 9.3 11.4 29 5.7 0.3 5.8 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat MFAP1 PF06991.11 EEQ36310.1 - 2.8 7.8 4.9 4.6 7.0 4.9 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Cwf_Cwc_15 PF04889.12 EEQ36310.1 - 4.9 6.8 11.2 7.7 6.2 11.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SH3_1 PF00018.28 EEQ36311.1 - 3e-07 29.9 0.0 1.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEQ36311.1 - 0.001 18.9 0.0 0.045 13.6 0.0 2.6 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EEQ36311.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain FTR1 PF03239.14 EEQ36312.1 - 1.8e-72 244.1 6.5 8.3e-49 166.4 4.0 2.0 1 1 0 2 2 2 2 Iron permease FTR1 family DUF3169 PF11368.8 EEQ36312.1 - 0.0053 16.3 1.9 0.012 15.1 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) PA PF02225.22 EEQ36313.1 - 1.8e-07 31.1 0.0 3.8e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.17 EEQ36313.1 - 6.5e-05 22.7 0.0 0.00021 21.0 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M28 DUF1296 PF06972.11 EEQ36313.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Sulfate_transp PF00916.20 EEQ36314.1 - 4.7e-71 239.5 23.5 6.6e-71 239.1 23.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEQ36314.1 - 4e-08 32.9 0.0 8.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 STAS domain PCDO_beta_N PF12391.8 EEQ36314.1 - 0.074 12.7 0.5 0.16 11.6 0.5 1.6 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal CENP-P PF13096.6 EEQ36314.1 - 0.083 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P E1_DerP2_DerF2 PF02221.15 EEQ36315.1 - 1.9e-27 96.3 0.2 2.2e-27 96.1 0.2 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EEQ36315.1 - 0.018 15.4 0.1 0.058 13.8 0.1 1.8 1 1 0 1 1 1 0 ML-like domain DUF4625 PF15418.6 EEQ36315.1 - 0.057 13.7 0.0 0.077 13.2 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4625) Alph_Pro_TM PF09608.10 EEQ36315.1 - 0.066 13.0 0.0 0.083 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Rad21_Rec8_N PF04825.13 EEQ36316.1 - 6.7e-17 61.6 0.0 1.4e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Pil1 PF13805.6 EEQ36317.1 - 3.7e-125 416.7 0.6 4.5e-125 416.5 0.6 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.10 EEQ36317.1 - 0.0062 16.7 4.2 0.18 12.0 0.3 3.4 3 0 0 3 3 3 1 Proto-chlorophyllide reductase 57 kD subunit Nop10p PF04135.12 EEQ36317.1 - 0.63 10.1 3.1 3.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Hat1_N PF10394.9 EEQ36318.1 - 4.4e-40 137.6 0.0 7.8e-40 136.7 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Archaeal_AmoA PF12942.7 EEQ36318.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Archaeal ammonia monooxygenase subunit A (AmoA) CT_A_B PF02626.15 EEQ36319.1 - 2.9e-91 305.8 0.0 6.3e-91 304.7 0.0 1.6 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B Amidase PF01425.21 EEQ36319.1 - 4.8e-90 302.7 0.1 6.8e-90 302.2 0.1 1.2 1 0 0 1 1 1 1 Amidase CPSase_L_D2 PF02786.17 EEQ36319.1 - 2.8e-61 206.7 0.0 5.3e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 EEQ36319.1 - 3.3e-43 147.8 0.0 7.2e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 EEQ36319.1 - 4.3e-42 143.1 0.2 1.1e-41 141.8 0.2 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EEQ36319.1 - 4.5e-33 113.6 0.0 1.2e-32 112.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EEQ36319.1 - 9.2e-18 63.9 3.9 9.2e-18 63.9 3.9 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EEQ36319.1 - 1.3e-09 37.9 0.0 2.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EEQ36319.1 - 6.9e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 EEQ36319.1 - 0.00017 21.5 0.2 0.00065 19.6 0.1 2.1 2 0 0 2 2 2 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 EEQ36319.1 - 0.001 18.9 2.6 0.11 12.3 0.3 3.1 1 1 1 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EEQ36319.1 - 0.001 19.1 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 EEQ36319.1 - 0.0036 16.8 0.0 0.012 15.1 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain NQRA PF05896.11 EEQ36319.1 - 0.028 13.9 0.1 0.051 13.0 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) NUDIX_5 PF16705.5 EEQ36319.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 NUDIX, or N-terminal NPxY motif-rich, region of KRIT SSF PF00474.17 EEQ36320.1 - 4.8e-17 61.9 28.8 1e-16 60.8 28.8 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family TraP PF07296.11 EEQ36320.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.0 2 0 0 2 2 2 0 TraP protein Sec62 PF03839.16 EEQ36320.1 - 0.2 11.1 0.2 0.43 10.1 0.2 1.5 1 0 0 1 1 1 0 Translocation protein Sec62 MttA_Hcf106 PF02416.16 EEQ36320.1 - 6.9 6.1 5.5 22 4.5 1.0 2.9 2 0 0 2 2 2 0 mttA/Hcf106 family EAP30 PF04157.16 EEQ36321.1 - 2.9e-29 102.0 1.6 2.9e-29 102.0 1.6 1.7 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EEQ36321.1 - 1.9e-23 82.4 0.0 4e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Vps36-NZF-N PF16988.5 EEQ36321.1 - 1.1e-06 27.9 4.5 1.1e-06 27.9 4.5 2.8 3 0 0 3 3 3 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-Sec23_Sec24 PF04810.15 EEQ36321.1 - 0.00037 20.5 3.5 0.05 13.7 0.4 2.7 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger ATP-synt_B PF00430.18 EEQ36321.1 - 0.0023 18.0 1.2 0.0048 17.0 1.2 1.5 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) DZR PF12773.7 EEQ36321.1 - 0.022 14.8 0.9 0.022 14.8 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon CheF-arch PF04283.12 EEQ36321.1 - 0.045 13.5 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Chemotaxis signal transduction system protein F from archaea MRNIP PF15749.5 EEQ36321.1 - 0.085 13.6 1.4 0.21 12.3 1.4 1.6 1 0 0 1 1 1 0 MRN-interacting protein Macoilin PF09726.9 EEQ36321.1 - 0.23 10.0 1.8 0.27 9.7 1.8 1.2 1 0 0 1 1 1 0 Macoilin family MDFI PF15316.6 EEQ36321.1 - 0.82 9.7 6.7 1.7 8.7 6.7 1.4 1 0 0 1 1 1 0 MyoD family inhibitor zf-RanBP PF00641.18 EEQ36321.1 - 1.9 7.9 14.5 0.83 9.0 2.4 3.0 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others Menin PF05053.13 EEQ36321.1 - 3.9 5.7 7.4 3.2 6.0 5.9 1.6 2 0 0 2 2 2 0 Menin Mo25 PF08569.11 EEQ36322.1 - 6.4e-118 393.8 5.2 7.3e-118 393.7 5.2 1.0 1 0 0 1 1 1 1 Mo25-like PrmC_N PF17827.1 EEQ36322.1 - 0.06 13.9 0.1 6.2 7.5 0.0 2.5 2 0 0 2 2 2 0 PrmC N-terminal domain Aminotran_4 PF01063.19 EEQ36323.1 - 3.1e-38 131.9 0.0 4.1e-38 131.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Glyco_hydro_47 PF01532.20 EEQ36324.1 - 2.2e-110 369.7 0.0 3.5e-110 369.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Trypan_PARP PF05887.11 EEQ36324.1 - 0.068 13.1 9.2 0.16 11.9 9.2 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sporozoite_P67 PF05642.11 EEQ36324.1 - 1.2 7.2 4.1 1.7 6.6 4.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1687 PF07955.11 EEQ36325.1 - 9.5e-34 116.6 0.1 1.2e-33 116.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Dynein_attach_N PF15867.5 EEQ36325.1 - 0.022 14.7 0.1 0.058 13.4 0.1 1.7 1 0 0 1 1 1 0 Dynein attachment factor N-terminus PTPLA PF04387.14 EEQ36326.1 - 9e-54 181.6 11.4 1.3e-53 181.2 11.4 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2070 PF09843.9 EEQ36326.1 - 0.18 10.1 7.7 0.21 9.8 7.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ChAPs PF09295.10 EEQ36329.1 - 5.7e-14 51.9 0.0 4e-08 32.7 0.0 3.3 3 0 0 3 3 3 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_16 PF13432.6 EEQ36329.1 - 6.1e-05 23.6 0.5 6.1e-05 23.6 0.5 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ36329.1 - 0.0023 18.4 0.1 0.0055 17.2 0.1 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36329.1 - 0.61 11.0 4.1 0.61 11.1 0.7 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 EEQ36330.1 - 1.5e-54 181.6 73.9 7.7e-11 41.6 3.5 10.0 5 3 3 10 10 10 8 Leucine rich repeat PP2C PF00481.21 EEQ36330.1 - 1.6e-38 132.8 0.0 3.5e-38 131.7 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 EEQ36330.1 - 4e-36 122.4 94.0 6.3e-06 26.4 0.4 13.8 9 2 8 17 17 17 12 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EEQ36330.1 - 1.9e-29 102.6 0.0 4.6e-29 101.3 0.0 1.5 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.33 EEQ36330.1 - 6.7e-09 35.1 68.4 0.93 10.3 1.0 16.9 15 3 1 16 16 16 3 Leucine Rich Repeat LRR_5 PF13306.6 EEQ36330.1 - 3.4e-06 27.0 19.6 0.00015 21.7 3.2 4.4 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 EEQ36330.1 - 0.00028 20.4 1.0 0.00028 20.4 1.0 5.4 3 1 3 6 6 6 3 Leucine-rich repeat AA_permease PF00324.21 EEQ36331.1 - 1.5e-70 238.2 39.1 1.8e-70 237.9 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ36331.1 - 1.6e-22 79.9 36.7 1.6e-22 79.9 36.7 1.4 1 1 0 1 1 1 1 Amino acid permease Gln-synt_C PF00120.24 EEQ36332.1 - 2.3e-21 76.2 0.0 6.5e-17 61.5 0.0 2.0 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EEQ36332.1 - 9.4e-12 44.5 0.0 1.9e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF1749 PF08538.10 EEQ36334.1 - 5.8e-86 288.3 0.0 6.5e-86 288.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 EEQ36334.1 - 8.8e-11 42.8 8.2 1.1e-10 42.5 8.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ36334.1 - 1.3e-06 27.9 0.0 1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF900 PF05990.12 EEQ36334.1 - 8e-06 25.5 0.0 1.5e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EEQ36334.1 - 0.0043 16.7 0.1 0.25 10.9 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ36334.1 - 0.0096 15.4 0.0 3.8 6.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 EEQ36334.1 - 0.01 15.7 0.0 0.031 14.1 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase LIDHydrolase PF10230.9 EEQ36334.1 - 0.039 13.5 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LCAT PF02450.15 EEQ36334.1 - 0.069 12.3 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1776 PF08643.10 EEQ36335.1 - 2.8e-78 263.3 0.0 3.7e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.6 EEQ36335.1 - 0.0065 16.1 0.0 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ36335.1 - 0.04 13.4 0.1 0.26 10.7 0.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase ICE2 PF08426.10 EEQ36336.1 - 3.9e-150 500.5 4.8 1.4e-149 498.6 4.8 1.7 1 1 0 1 1 1 1 ICE2 Presenilin PF01080.17 EEQ36336.1 - 0.0041 15.9 0.1 0.0069 15.2 0.1 1.4 1 0 0 1 1 1 1 Presenilin Zip PF02535.22 EEQ36336.1 - 0.0071 15.6 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter RR_TM4-6 PF06459.12 EEQ36336.1 - 0.011 15.6 0.8 0.014 15.2 0.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4834 PF16118.5 EEQ36336.1 - 0.029 15.3 1.5 0.056 14.4 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PBP1_TM PF14812.6 EEQ36336.1 - 0.071 13.5 3.6 0.12 12.8 3.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Connexin PF00029.19 EEQ36336.1 - 0.14 11.9 0.5 0.24 11.1 0.5 1.4 1 0 0 1 1 1 0 Connexin V_ATPase_I PF01496.19 EEQ36336.1 - 0.17 9.7 0.9 0.25 9.2 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RP-C_C PF11800.8 EEQ36336.1 - 0.27 11.3 3.7 0.43 10.6 3.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Orf78 PF06024.12 EEQ36336.1 - 0.28 11.5 0.7 0.65 10.3 0.7 1.6 1 0 0 1 1 1 0 Orf78 (ac78) Pox_Ag35 PF03286.14 EEQ36336.1 - 0.35 10.7 8.5 0.51 10.1 8.5 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 EEQ36336.1 - 0.43 9.9 10.7 0.41 10.0 8.6 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 EEQ36336.1 - 0.51 8.6 8.6 0.69 8.1 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4228 PF14009.6 EEQ36336.1 - 0.97 9.8 4.1 0.24 11.8 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DUF4637 PF15470.6 EEQ36336.1 - 1.8 8.3 7.5 3.2 7.5 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Tim54 PF11711.8 EEQ36336.1 - 3.2 6.5 6.1 4.5 5.9 6.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF4820 PF16091.5 EEQ36336.1 - 4.7 6.5 6.2 8.7 5.6 6.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) UTP25 PF06862.12 EEQ36337.1 - 3.1e-190 633.0 0.2 3.7e-190 632.7 0.2 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EEQ36337.1 - 0.0016 18.2 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase RPOL_N PF14700.6 EEQ36337.1 - 0.13 11.6 1.8 0.22 10.9 1.8 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Nop14 PF04147.12 EEQ36337.1 - 1.2 7.3 15.8 1.6 6.8 15.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 EEQ36337.1 - 5.1 6.4 16.5 9.3 5.5 16.5 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Rad10 PF03834.14 EEQ36339.1 - 8.5e-41 138.6 0.0 1.4e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Macoilin PF09726.9 EEQ36339.1 - 0.16 10.5 11.7 0.2 10.2 11.7 1.1 1 0 0 1 1 1 0 Macoilin family Zip PF02535.22 EEQ36339.1 - 0.5 9.5 5.7 0.66 9.1 5.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 EEQ36339.1 - 0.63 8.8 5.2 0.73 8.6 5.2 1.2 1 0 0 1 1 1 0 Otopetrin DUF4551 PF15087.6 EEQ36339.1 - 0.78 8.5 16.9 1 8.1 16.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 EEQ36339.1 - 0.81 8.4 19.6 1.1 7.9 19.6 1.2 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 EEQ36339.1 - 0.82 8.7 14.2 0.98 8.4 14.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Lin-8 PF03353.15 EEQ36339.1 - 2.6 7.5 18.7 3.8 7.0 18.7 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Menin PF05053.13 EEQ36339.1 - 2.9 6.2 11.7 3.6 5.8 11.7 1.3 1 0 0 1 1 1 0 Menin ASD2 PF08687.11 EEQ36339.1 - 3 7.3 12.2 4.1 6.9 12.2 1.3 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 FAM60A PF15396.6 EEQ36339.1 - 4.8 7.1 11.8 7.4 6.5 11.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_S64 PF08192.11 EEQ36339.1 - 4.9 5.5 13.9 6.4 5.1 13.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 EEQ36339.1 - 5.9 5.4 15.3 8.8 4.9 15.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Prefoldin PF02996.17 EEQ36340.1 - 9.6e-26 90.1 4.1 1.2e-25 89.7 4.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit FliD_N PF02465.18 EEQ36340.1 - 0.035 14.8 5.6 0.18 12.5 0.8 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus AATF-Che1 PF13339.6 EEQ36340.1 - 0.038 14.7 3.2 0.11 13.2 0.2 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Annexin PF00191.20 EEQ36340.1 - 0.063 13.3 0.7 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 Annexin Nas2_N PF18265.1 EEQ36340.1 - 0.074 13.0 2.8 2.3 8.2 0.3 2.5 2 2 0 2 2 2 0 Nas2 N_terminal domain APC_N_CC PF16689.5 EEQ36340.1 - 0.11 12.5 0.6 0.11 12.5 0.6 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Spc24 PF08286.11 EEQ36340.1 - 0.19 12.0 6.4 0.64 10.3 6.4 1.8 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 EEQ36340.1 - 0.25 11.3 10.2 0.35 10.8 1.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit LRRFIP PF09738.9 EEQ36340.1 - 0.35 10.3 7.9 3.2 7.1 0.2 2.0 2 0 0 2 2 2 0 LRRFIP family CLZ PF16526.5 EEQ36340.1 - 0.38 11.1 5.1 0.21 11.9 0.8 2.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels V-SNARE PF05008.15 EEQ36340.1 - 0.4 11.1 8.3 0.24 11.8 1.9 2.5 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF1664 PF07889.12 EEQ36340.1 - 0.5 10.4 6.2 1.4 9.0 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.14 EEQ36340.1 - 1 9.3 8.9 0.8 9.6 1.3 2.1 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TMF_TATA_bd PF12325.8 EEQ36340.1 - 1.1 9.5 9.7 0.39 10.9 2.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 EEQ36340.1 - 1.4 9.0 11.7 2.3 8.3 3.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Rtf2 PF04641.12 EEQ36341.1 - 2.4e-37 128.7 0.8 4.9e-37 127.7 0.8 1.5 1 1 0 1 1 1 1 Rtf2 RING-finger NAD_Gly3P_dh_N PF01210.23 EEQ36342.1 - 0.003 17.6 0.1 0.28 11.2 0.0 2.4 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Peptidase_S10 PF00450.22 EEQ36343.1 - 6.3e-127 424.5 0.0 9.7e-127 423.8 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase AA_permease_2 PF13520.6 EEQ36345.1 - 1.5e-63 215.1 53.4 1.8e-63 214.9 53.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ36345.1 - 6.9e-13 48.0 45.9 1.1e-12 47.3 45.9 1.2 1 0 0 1 1 1 1 Amino acid permease DUF5045 PF16464.5 EEQ36345.1 - 0.21 11.9 0.1 0.41 11.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) Ribosomal_L30 PF00327.20 EEQ36346.1 - 4.3e-11 42.5 0.2 8.6e-11 41.6 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e UPF0242 PF06785.11 EEQ36347.1 - 0.00014 22.0 5.6 0.00026 21.1 5.6 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF1689 PF07954.11 EEQ36347.1 - 0.06 13.7 2.0 1 9.7 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) Syntaxin-6_N PF09177.11 EEQ36347.1 - 0.16 12.5 4.2 0.075 13.6 1.2 2.0 2 1 0 2 2 2 0 Syntaxin 6, N-terminal PLU-1 PF08429.11 EEQ36348.1 - 5.9e-45 153.9 8.3 1.6e-44 152.5 8.3 1.7 1 0 0 1 1 1 1 PLU-1-like protein JmjC PF02373.22 EEQ36348.1 - 1.3e-19 70.7 1.5 7.7e-10 39.2 0.0 2.8 2 0 0 2 2 2 2 JmjC domain, hydroxylase ARID PF01388.21 EEQ36348.1 - 1.9e-14 54.1 0.0 1.3e-13 51.5 0.0 2.6 1 1 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 EEQ36348.1 - 3.1e-08 33.4 9.5 6.2e-08 32.4 9.5 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EEQ36348.1 - 0.072 13.3 2.4 0.22 11.7 2.4 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EEQ36348.1 - 0.077 13.3 5.0 0.04 14.2 2.1 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain DUF3741 PF12552.8 EEQ36348.1 - 0.083 12.9 2.2 0.64 10.0 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3741) zf-RING_2 PF13639.6 EEQ36348.1 - 2.4 8.6 6.3 7.1 7.0 6.3 1.8 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 EEQ36348.1 - 3.2 7.9 7.1 9.5 6.4 7.1 1.8 1 0 0 1 1 1 0 PHD-finger Flocculin_t3 PF13928.6 EEQ36349.1 - 0.022 15.3 9.7 0.022 15.3 9.7 3.5 1 1 2 3 3 3 0 Flocculin type 3 repeat BRCT PF00533.26 EEQ36351.1 - 7.5e-24 83.9 0.0 2.9e-09 37.2 0.0 4.7 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEQ36351.1 - 1.1e-20 73.4 6.4 1.9e-07 31.0 0.3 4.7 5 0 0 5 5 5 3 twin BRCT domain BRCT_2 PF16589.5 EEQ36351.1 - 1.9e-11 44.2 0.0 0.00015 22.1 0.0 4.2 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EEQ36351.1 - 0.0073 16.6 3.4 1.6 9.1 0.0 4.3 5 0 0 5 5 5 1 DNA ligase 3 BRCT domain DASH_Duo1 PF08651.10 EEQ36351.1 - 0.012 15.4 0.3 0.031 14.1 0.3 1.7 1 0 0 1 1 1 0 DASH complex subunit Duo1 Neurensin PF14927.6 EEQ36351.1 - 0.13 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Neurensin GTP_EFTU PF00009.27 EEQ36352.1 - 8.4e-55 185.3 0.7 1.6e-54 184.4 0.0 1.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEQ36352.1 - 6.5e-43 145.6 0.0 1.4e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEQ36352.1 - 1.1e-13 51.4 2.2 1.1e-13 51.4 2.2 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ36352.1 - 0.0004 20.4 0.1 0.011 15.8 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF1771 PF08590.10 EEQ36354.1 - 4.6e-16 58.9 10.9 7.7e-16 58.2 10.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EEQ36354.1 - 1.1e-10 41.7 0.4 2.4e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 Smr domain Ax_dynein_light PF10211.9 EEQ36354.1 - 0.00051 20.0 1.5 0.00095 19.2 1.5 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain Seryl_tRNA_N PF02403.22 EEQ36354.1 - 0.49 10.6 3.8 0.88 9.8 3.8 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Spt20 PF12090.8 EEQ36354.1 - 1.1 8.8 23.3 0.078 12.6 11.5 2.1 2 0 0 2 2 2 0 Spt20 family DUF2076 PF09849.9 EEQ36354.1 - 2.7 8.0 15.6 0.033 14.2 6.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 EEQ36354.1 - 4.3 8.0 12.0 0.47 11.1 4.7 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ras PF00071.22 EEQ36356.1 - 4.8e-52 175.8 0.2 6e-52 175.5 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ36356.1 - 4.4e-34 117.3 0.1 6.6e-34 116.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ36356.1 - 2.4e-15 56.4 0.1 3e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEQ36356.1 - 8.1e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEQ36356.1 - 1e-06 28.3 0.4 1.3e-06 28.0 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEQ36356.1 - 6.9e-06 25.7 0.1 0.00014 21.4 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ36356.1 - 3e-05 24.0 0.3 0.023 14.6 0.2 2.6 1 1 2 3 3 3 2 RsgA GTPase ATP_bind_1 PF03029.17 EEQ36356.1 - 0.00012 21.9 0.3 0.0099 15.7 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EEQ36356.1 - 0.00039 19.9 0.1 0.00075 19.0 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EEQ36356.1 - 0.0011 19.3 0.0 0.0083 16.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.9 EEQ36356.1 - 0.0017 18.1 0.4 0.0048 16.6 0.4 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EEQ36356.1 - 0.0032 17.9 0.0 0.0045 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EEQ36356.1 - 0.0042 17.0 0.1 0.0043 17.0 0.1 1.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 EEQ36356.1 - 0.0059 16.5 0.0 0.0089 16.0 0.0 1.3 1 0 0 1 1 1 1 NACHT domain cobW PF02492.19 EEQ36356.1 - 0.0059 16.2 0.1 0.017 14.8 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EEQ36356.1 - 0.0079 15.5 0.3 0.018 14.3 0.1 1.7 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 EEQ36356.1 - 0.01 15.6 0.1 0.035 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEQ36356.1 - 0.014 14.9 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 EEQ36356.1 - 0.023 13.8 1.7 0.052 12.7 1.7 1.8 1 1 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.22 EEQ36356.1 - 0.026 13.7 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain TniB PF05621.11 EEQ36356.1 - 0.03 13.7 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_14 PF13173.6 EEQ36356.1 - 0.035 14.2 0.2 0.17 11.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EEQ36356.1 - 0.058 13.4 0.1 0.25 11.3 0.0 2.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) MCM PF00493.23 EEQ36356.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 EEQ36356.1 - 0.085 13.4 0.4 0.11 13.1 0.4 1.6 1 1 0 1 1 1 0 ABC transporter Aldo_ket_red PF00248.21 EEQ36357.1 - 1.1e-29 103.6 0.0 2.3e-27 96.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4375 PF14300.6 EEQ36357.1 - 0.12 12.6 0.1 0.33 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) FMN_red PF03358.15 EEQ36358.1 - 2.6e-09 37.0 0.0 4.1e-09 36.4 0.0 1.3 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EEQ36358.1 - 0.00069 19.4 0.0 0.00085 19.1 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 EEQ36358.1 - 0.0013 19.0 0.0 0.0019 18.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Paf1 PF03985.13 EEQ36360.1 - 2.5e-89 300.2 24.3 2.8e-89 300.1 24.3 1.0 1 0 0 1 1 1 1 Paf1 MINDY_DUB PF04424.13 EEQ36361.1 - 1.9e-13 50.4 0.0 7e-13 48.6 0.0 1.8 2 1 0 2 2 2 1 MINDY deubiquitinase CCDC50_N PF15295.6 EEQ36361.1 - 0.16 12.1 3.9 0.28 11.3 3.9 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus RNA_polI_A34 PF08208.11 EEQ36361.1 - 5.3 7.1 14.8 82 3.2 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S49_N PF08496.10 EEQ36361.1 - 7.5 6.6 8.7 13 5.8 8.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SQS_PSY PF00494.19 EEQ36362.1 - 3.2e-43 148.1 0.0 4.1e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Gtr1_RagA PF04670.12 EEQ36363.1 - 7e-94 313.5 5.6 9.2e-94 313.1 5.6 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EEQ36363.1 - 1.9e-08 34.0 0.1 3.7e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ36363.1 - 7.7e-08 32.6 0.0 2.3e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ36363.1 - 1.5e-07 31.1 0.8 3e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEQ36363.1 - 7.7e-07 29.2 0.0 1.6e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EEQ36363.1 - 0.015 15.9 0.3 0.035 14.6 0.1 1.9 2 1 0 2 2 2 0 ABC transporter DUF815 PF05673.13 EEQ36363.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 EEQ36363.1 - 0.046 13.5 1.1 0.11 12.3 0.4 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Prefoldin_2 PF01920.20 EEQ36363.1 - 0.18 11.8 3.7 4.7 7.2 0.2 2.7 2 1 0 2 2 2 0 Prefoldin subunit RsgA_GTPase PF03193.16 EEQ36363.1 - 0.39 10.6 5.2 1.4 8.8 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase MFS_1 PF07690.16 EEQ36364.1 - 2.8e-17 62.7 21.0 2.8e-16 59.4 21.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Mvb12 PF09452.10 EEQ36364.1 - 0.15 12.5 2.1 0.69 10.4 2.2 1.9 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 DUF4010 PF13194.6 EEQ36365.1 - 0.15 11.7 3.5 0.18 11.5 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Metallophos PF00149.28 EEQ36366.1 - 6.6e-11 43.1 8.2 1.1e-10 42.4 2.7 3.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase zf-trcl PF13451.6 EEQ36366.1 - 0.62 10.0 2.8 8.1 6.4 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-ribbon domain Metallophos PF00149.28 EEQ36367.1 - 1.2e-09 38.9 6.3 1.2e-09 38.9 6.3 2.6 3 1 0 3 3 3 1 Calcineurin-like phosphoesterase DUF1579 PF07617.11 EEQ36367.1 - 0.079 12.9 0.2 0.19 11.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1579) RRM_1 PF00076.22 EEQ36369.1 - 4.1e-15 55.4 0.0 6.3e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EEQ36370.1 - 5.5e-18 65.3 0.1 1e-17 64.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36370.1 - 1.1e-08 34.7 0.0 2.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FAD_binding_2 PF00890.24 EEQ36372.1 - 2.1e-123 412.5 3.4 2.6e-123 412.2 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EEQ36372.1 - 4.6e-44 149.5 0.5 7e-44 148.9 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 EEQ36372.1 - 5.1e-06 25.8 1.3 0.0019 17.3 1.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EEQ36372.1 - 6.1e-06 25.7 0.1 0.00012 21.4 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ36372.1 - 8.1e-06 25.2 0.3 0.0068 15.7 0.1 2.5 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EEQ36372.1 - 0.0027 17.0 0.2 0.006 15.9 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EEQ36372.1 - 0.015 14.0 0.0 0.27 9.9 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 EEQ36372.1 - 0.015 14.9 1.3 0.056 13.0 1.3 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase ATP-synt_D PF01813.17 EEQ36374.1 - 9.5e-70 234.4 7.2 9.5e-70 234.4 7.2 1.7 2 0 0 2 2 2 1 ATP synthase subunit D BUD22 PF09073.10 EEQ36374.1 - 0.0053 16.2 17.0 0.0089 15.4 17.0 1.3 1 0 0 1 1 1 1 BUD22 PGA2 PF07543.12 EEQ36374.1 - 0.081 12.9 20.2 0.18 11.8 20.2 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF3381 PF11861.8 EEQ36374.1 - 0.53 10.1 20.0 0.036 13.9 14.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 EEQ36374.1 - 0.56 8.4 18.4 0.8 7.9 18.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 EEQ36374.1 - 1.2 7.2 11.0 1.5 6.8 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.12 EEQ36374.1 - 1.4 7.8 7.4 2.3 7.1 7.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 EEQ36374.1 - 1.5 8.5 17.8 0.25 11.1 14.4 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 EEQ36374.1 - 5.3 5.5 12.4 7.6 4.9 12.4 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4228 PF14009.6 EEQ36374.1 - 5.8 7.3 8.2 1.4 9.3 4.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) YqfQ PF14181.6 EEQ36374.1 - 9.1 6.4 20.2 12 6.1 18.9 1.8 1 1 0 1 1 1 0 YqfQ-like protein Trm112p PF03966.16 EEQ36375.1 - 2.3e-19 69.8 0.1 3.3e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein Novirhabdo_Nv PF05554.11 EEQ36375.1 - 0.092 12.5 0.1 0.19 11.5 0.1 1.5 1 1 0 1 1 1 0 Viral hemorrhagic septicemia virus non-virion protein THP2 PF09432.10 EEQ36377.1 - 7.7 6.6 7.7 1.5 8.9 1.6 2.7 1 1 1 2 2 2 0 Tho complex subunit THP2 TRAP_alpha PF03896.16 EEQ36380.1 - 0.0091 15.2 0.0 0.11 11.6 0.0 2.1 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Syja_N PF02383.18 EEQ36381.1 - 4.5e-53 180.6 0.2 9.6e-53 179.6 0.2 1.5 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EEQ36381.1 - 4.3e-09 36.2 0.0 7.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family HMGL-like PF00682.19 EEQ36383.1 - 2e-80 270.1 0.0 2.8e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EEQ36383.1 - 3.1e-27 95.1 0.0 4.9e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Sugar_tr PF00083.24 EEQ36384.1 - 2.6e-51 174.9 28.6 1.3e-50 172.6 28.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36384.1 - 1.1e-19 70.6 49.9 8.6e-17 61.1 29.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 EEQ36384.1 - 0.00072 17.9 2.4 0.14 10.3 0.2 2.3 2 0 0 2 2 2 2 BT1 family DMT_YdcZ PF04657.13 EEQ36384.1 - 0.0041 17.4 0.6 0.0041 17.4 0.6 3.6 2 1 1 3 3 3 1 Putative inner membrane exporter, YdcZ MFS_3 PF05977.13 EEQ36384.1 - 0.0046 15.4 0.2 0.032 12.7 0.1 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.6 EEQ36384.1 - 0.0074 14.9 21.3 0.69 8.4 1.0 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein RSN1_7TM PF02714.15 EEQ36385.1 - 1.7e-81 273.6 25.5 1.7e-81 273.6 25.5 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEQ36385.1 - 1.5e-43 148.3 2.3 1.5e-43 148.3 2.3 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EEQ36385.1 - 3.3e-30 105.6 0.2 7e-30 104.6 0.2 1.6 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EEQ36385.1 - 4.6e-23 81.2 0.6 8.5e-23 80.4 0.2 1.7 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter Remorin_C PF03763.13 EEQ36385.1 - 0.059 13.3 0.6 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 Remorin, C-terminal region RCR PF12273.8 EEQ36386.1 - 8.8e-39 132.8 3.7 8.8e-39 132.8 3.7 2.8 3 0 0 3 3 3 2 Chitin synthesis regulation, resistance to Congo red DUF4051 PF13260.6 EEQ36386.1 - 0.32 10.8 1.3 0.44 10.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) TP6A_N PF04406.14 EEQ36388.1 - 5.8e-17 61.4 0.3 1e-16 60.7 0.3 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Pyrophosphatase PF00719.19 EEQ36389.1 - 6.2e-59 198.4 0.3 8.3e-59 198.0 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Rad51 PF08423.11 EEQ36390.1 - 3.6e-20 72.3 0.0 4.3e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EEQ36390.1 - 4.9e-07 29.5 0.0 1.1e-06 28.4 0.0 1.5 1 1 1 2 2 2 1 AAA domain ATPase PF06745.13 EEQ36390.1 - 3.7e-06 26.4 0.1 1.1e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 KaiC RecA PF00154.21 EEQ36390.1 - 0.00077 19.0 0.0 0.00099 18.6 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ABC_tran PF00005.27 EEQ36390.1 - 0.0044 17.5 0.4 0.013 16.0 0.1 1.8 1 1 1 2 2 2 1 ABC transporter DnaB_C PF03796.15 EEQ36390.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EEQ36390.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EEQ36390.1 - 0.057 13.3 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 EEQ36390.1 - 0.06 13.2 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EEQ36390.1 - 0.079 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase PAXNEB PF05625.11 EEQ36390.1 - 0.095 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 PAXNEB protein RNA_helicase PF00910.22 EEQ36390.1 - 0.13 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Rad51 PF08423.11 EEQ36391.1 - 3.4e-06 26.5 0.5 1e-05 24.9 0.2 1.8 2 1 0 2 2 2 1 Rad51 Maf1 PF09174.10 EEQ36392.1 - 8.9e-27 94.3 6.2 9.5e-19 68.2 0.1 2.3 2 0 0 2 2 2 2 Maf1 regulator Astro_capsid_p PF12226.8 EEQ36392.1 - 0.38 9.9 4.3 0.52 9.4 4.3 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Aldo_ket_red PF00248.21 EEQ36393.1 - 3.9e-40 137.9 0.3 2.5e-38 131.9 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4535 PF15054.6 EEQ36393.1 - 0.096 12.4 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) GntR PF00392.21 EEQ36393.1 - 0.12 12.1 0.0 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Bacterial regulatory proteins, gntR family Pyrid_oxidase_2 PF13883.6 EEQ36394.1 - 4.2e-56 189.5 0.0 5e-56 189.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase His_biosynth PF00977.21 EEQ36395.1 - 1.1e-44 152.6 0.0 8.7e-44 149.7 0.0 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EEQ36395.1 - 3.7e-13 49.7 0.0 8e-13 48.6 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EEQ36395.1 - 1.9e-06 27.6 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiG PF05690.14 EEQ36395.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG Peptidase_S51 PF03575.17 EEQ36395.1 - 0.086 12.5 0.0 0.21 11.2 0.0 1.5 1 1 0 1 1 1 0 Peptidase family S51 DUF4438 PF14505.6 EEQ36395.1 - 0.14 11.1 0.5 0.4 9.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4438) Methyltransf_25 PF13649.6 EEQ36396.1 - 0.0012 19.5 0.0 0.0029 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ36396.1 - 0.0053 17.4 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DNA_pol_A_exo1 PF01612.20 EEQ36397.1 - 1.4e-45 155.2 1.8 1.4e-45 155.2 1.8 2.1 3 0 0 3 3 3 1 3'-5' exonuclease PMC2NT PF08066.12 EEQ36397.1 - 3.4e-20 72.5 1.6 3.4e-20 72.5 1.6 4.3 5 1 0 5 5 5 1 PMC2NT (NUC016) domain HRDC PF00570.23 EEQ36397.1 - 2.5e-09 37.0 0.1 1.1e-08 34.9 0.0 2.1 2 0 0 2 2 2 1 HRDC domain zf-C2H2_2 PF12756.7 EEQ36398.1 - 8.8e-37 125.5 1.4 4.8e-33 113.5 0.4 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EEQ36398.1 - 4.8e-06 26.7 0.9 0.12 12.7 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EEQ36398.1 - 0.027 14.9 6.1 0.41 11.2 0.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type Nop25 PF09805.9 EEQ36398.1 - 0.4 11.1 19.7 0.23 11.9 7.8 2.6 2 1 0 2 2 2 0 Nucleolar protein 12 (25kDa) Presenilin PF01080.17 EEQ36398.1 - 0.45 9.2 1.6 0.7 8.6 1.6 1.3 1 0 0 1 1 1 0 Presenilin DUF5338 PF17273.2 EEQ36398.1 - 1.7 8.8 5.1 25 5.0 1.7 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5338) zf-C2H2_4 PF13894.6 EEQ36398.1 - 2.9 9.0 6.6 3.6 8.7 0.0 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger Phosphodiest PF01663.22 EEQ36399.1 - 9.2e-12 45.2 1.8 1.6e-07 31.2 0.1 2.1 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EEQ36399.1 - 3.9e-05 23.2 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EEQ36399.1 - 0.0003 20.2 0.0 0.0006 19.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF229 PF02995.17 EEQ36399.1 - 0.077 11.6 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) GED PF02212.18 EEQ36399.1 - 0.15 12.2 0.1 0.36 11.0 0.1 1.6 1 0 0 1 1 1 0 Dynamin GTPase effector domain RCC1 PF00415.18 EEQ36400.1 - 7.6e-64 212.2 0.0 3e-11 43.8 0.0 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEQ36400.1 - 2.2e-39 132.5 20.2 6.4e-09 35.4 0.1 6.8 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat sCache_3_2 PF17203.4 EEQ36400.1 - 0.052 13.7 0.0 5.9 7.0 0.0 3.1 2 1 1 3 3 3 0 Single cache domain 3 Umbravirus_LDM PF04817.12 EEQ36400.1 - 0.061 12.7 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Chitin_synth_1 PF01644.17 EEQ36401.1 - 2e-74 249.0 0.6 3.4e-74 248.2 0.6 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 EEQ36401.1 - 3.3e-27 95.3 4.7 3.7e-21 75.3 0.0 3.1 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 EEQ36401.1 - 1.7e-23 82.4 0.0 4e-23 81.2 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 EEQ36401.1 - 4.3e-09 36.6 0.1 4.3e-09 36.6 0.1 2.6 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EEQ36401.1 - 0.013 15.4 0.0 0.5 10.2 0.0 2.6 3 0 0 3 3 3 0 Glycosyltransferase like family 2 DUF3611 PF12263.8 EEQ36401.1 - 0.93 9.4 7.1 0.3 11.0 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Tmemb_55A PF09788.9 EEQ36401.1 - 3.8 6.5 8.4 1 8.4 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A HbrB PF08539.11 EEQ36402.1 - 1.4e-06 28.4 0.5 1.4e-05 25.2 0.5 2.7 1 1 0 1 1 1 1 HbrB-like Sld5 PF05916.11 EEQ36403.1 - 2.1e-24 86.1 0.4 3.2e-24 85.5 0.4 1.3 1 0 0 1 1 1 1 GINS complex protein NAT PF04768.13 EEQ36404.1 - 6.8e-42 143.0 0.1 1.7e-41 141.7 0.1 1.7 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DUF4374 PF14298.6 EEQ36404.1 - 0.019 13.8 0.0 0.041 12.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4374) HlyIII PF03006.20 EEQ36405.1 - 3.8e-52 177.2 8.5 4.8e-52 176.9 8.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF92 PF01940.16 EEQ36405.1 - 0.044 13.2 0.5 4.6 6.6 0.3 2.6 2 1 0 2 2 2 0 Integral membrane protein DUF92 DUF218 PF02698.17 EEQ36406.1 - 0.0067 16.4 0.0 0.0097 15.9 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain DAHP_synth_1 PF00793.20 EEQ36407.1 - 1.2e-108 362.2 0.1 1.5e-108 361.8 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CLN3 PF02487.17 EEQ36408.1 - 7.2e-145 483.0 14.2 8.9e-145 482.7 14.2 1.1 1 0 0 1 1 1 1 CLN3 protein MFS_1 PF07690.16 EEQ36408.1 - 7.7e-05 21.8 28.8 0.00076 18.5 28.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ36408.1 - 0.00046 19.2 1.0 0.00046 19.2 1.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4491 PF14898.6 EEQ36408.1 - 0.054 13.9 0.5 0.054 13.9 0.5 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4491) Acyltransferase PF01553.21 EEQ36409.1 - 1.2e-15 57.3 0.0 3.4e-15 55.8 0.0 1.8 1 1 1 2 2 2 1 Acyltransferase Gly_transf_sug PF04488.15 EEQ36410.1 - 3.7e-22 78.8 0.0 9e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Band_7 PF01145.25 EEQ36411.1 - 1.3e-27 96.9 0.1 2e-27 96.3 0.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EEQ36411.1 - 4.1e-24 84.4 0.1 1.1e-23 83.0 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Pox_A11 PF05061.13 EEQ36411.1 - 0.027 13.8 0.1 0.046 13.0 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A11 Protein Band_7_1 PF13421.6 EEQ36411.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family RNase_PH PF01138.21 EEQ36412.1 - 1.1e-21 77.7 0.0 1.8e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEQ36412.1 - 3e-09 36.8 0.2 8.4e-09 35.3 0.1 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_H2-Ydr279 PF09468.10 EEQ36413.1 - 1.2e-21 77.5 0.1 1.2e-21 77.5 0.1 1.8 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EEQ36413.1 - 1e-07 32.1 0.0 2.4e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Med3 PF11593.8 EEQ36413.1 - 0.074 12.2 0.7 0.12 11.6 0.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Phage_holin_6_1 PF09682.10 EEQ36413.1 - 0.14 12.6 4.9 0.29 11.6 4.9 1.6 1 0 0 1 1 1 0 Bacteriophage holin of superfamily 6 (Holin_LLH) LrgB PF04172.16 EEQ36414.1 - 6.6e-51 172.9 2.6 6.6e-51 172.9 2.6 2.3 2 0 0 2 2 2 1 LrgB-like family LrgA PF03788.14 EEQ36414.1 - 0.00028 20.8 6.0 0.00028 20.8 6.0 3.9 4 1 0 4 4 4 1 LrgA family zf-CHCC PF10276.9 EEQ36415.1 - 3.7e-16 58.9 0.6 6.1e-16 58.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger domain zf_C2H2_6 PF18450.1 EEQ36415.1 - 0.056 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Zinc Finger domain PrlF_antitoxin PF15937.5 EEQ36415.1 - 0.08 13.4 0.1 0.21 12.0 0.1 1.7 1 1 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin Ras PF00071.22 EEQ36416.1 - 1.7e-55 187.1 0.0 2e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ36416.1 - 3.8e-22 78.8 0.0 6.4e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ36416.1 - 1.3e-07 31.3 0.0 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ36416.1 - 0.0011 18.6 0.0 0.003 17.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEQ36416.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EEQ36416.1 - 0.043 13.7 0.1 0.14 12.1 0.0 1.9 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 EEQ36416.1 - 0.05 12.9 0.0 0.064 12.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region tRNA_m1G_MT PF01746.21 EEQ36417.1 - 2.8e-29 102.2 0.1 5.3e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Aldo_ket_red PF00248.21 EEQ36418.1 - 1.4e-31 109.8 0.1 2.1e-29 102.7 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 EEQ36419.1 - 1.2e-09 38.1 10.3 3.3e-09 36.7 10.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PQ-loop PF04193.14 EEQ36420.1 - 3.1e-39 132.6 18.5 5.4e-22 77.3 1.4 3.0 3 0 0 3 3 3 2 PQ loop repeat Bac_export_2 PF01312.19 EEQ36420.1 - 0.62 9.2 1.5 0.74 9.0 0.1 1.7 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family tRNA_int_end_N2 PF12928.7 EEQ36421.1 - 3.2e-19 68.9 0.0 6.3e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EEQ36421.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain RgpF PF05045.12 EEQ36421.1 - 0.079 11.7 0.8 0.12 11.1 0.8 1.2 1 0 0 1 1 1 0 Rhamnan synthesis protein F DUF2779 PF11074.8 EEQ36422.1 - 0.11 13.0 1.2 0.24 11.8 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) Smg4_UPF3 PF03467.15 EEQ36423.1 - 1.2e-21 77.5 0.3 1.2e-21 77.5 0.3 3.9 3 1 1 4 4 4 1 Smg-4/UPF3 family PCI PF01399.27 EEQ36424.1 - 0.037 14.5 0.0 0.099 13.2 0.0 1.8 1 1 0 1 1 1 0 PCI domain Ferric_reduct PF01794.19 EEQ36426.1 - 1.6e-17 63.8 8.9 4e-17 62.5 8.9 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ36426.1 - 0.011 15.9 0.2 0.19 11.9 0.2 2.7 1 1 0 1 1 1 0 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ36426.1 - 0.016 15.3 0.1 0.043 13.9 0.1 1.7 1 0 0 1 1 1 0 FAD-binding domain DUF2701 PF10857.8 EEQ36426.1 - 9.9 6.3 7.2 4.7 7.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2701) zf-CCHC PF00098.23 EEQ36427.1 - 4.3e-06 26.6 35.0 0.0014 18.6 1.0 5.2 5 0 0 5 5 5 4 Zinc knuckle zf-CCHC_5 PF14787.6 EEQ36427.1 - 0.019 14.7 1.6 0.019 14.7 1.6 4.3 2 1 2 4 4 4 0 GAG-polyprotein viral zinc-finger zf-C2H2_10 PF16588.5 EEQ36427.1 - 0.023 14.4 13.8 0.21 11.4 5.0 2.8 2 0 0 2 2 2 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 EEQ36427.1 - 0.062 13.1 20.6 0.22 11.4 0.6 4.0 3 0 0 3 3 3 0 Zinc knuckle Cg6151-P PF10233.9 EEQ36428.1 - 7.9e-42 142.1 12.2 1.1e-41 141.7 12.2 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 EEQ36428.1 - 1.5 8.9 15.7 1.8 8.6 15.1 1.5 1 1 0 1 1 1 0 COPI associated protein Phage_holin_3_6 PF07332.11 EEQ36428.1 - 3.5 7.7 9.6 5.7 7.0 0.5 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF5090 PF17009.5 EEQ36428.1 - 3.9 7.4 12.7 2.1 8.3 4.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) DUF2207 PF09972.9 EEQ36428.1 - 8.6 5.0 12.8 0.3 9.8 5.7 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MMR_HSR1_C PF08438.10 EEQ36429.1 - 6.2e-33 113.7 0.0 1.1e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EEQ36429.1 - 1.7e-20 73.2 0.0 6.6e-20 71.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ36429.1 - 8.9e-07 28.6 0.1 8.9e-07 28.6 0.1 3.0 3 0 0 3 3 3 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EEQ36429.1 - 0.013 15.0 1.5 0.57 9.7 0.0 2.9 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 EEQ36429.1 - 0.017 14.1 1.6 0.025 13.5 0.0 2.1 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EEQ36429.1 - 0.019 15.0 0.0 0.05 13.7 0.0 1.7 1 0 0 1 1 1 0 Dynamin family RsgA_GTPase PF03193.16 EEQ36429.1 - 0.034 14.1 0.4 5.6 6.8 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EEQ36429.1 - 0.044 14.3 0.0 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EEQ36429.1 - 0.063 13.7 0.1 0.85 10.0 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EEQ36429.1 - 0.23 11.7 0.6 0.41 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain CRAL_TRIO PF00650.20 EEQ36430.1 - 6.3e-21 74.7 0.0 1.2e-20 73.8 0.0 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ36430.1 - 0.0011 19.2 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SLM4 PF16818.5 EEQ36430.1 - 0.042 13.8 1.0 0.069 13.1 0.1 1.8 2 0 0 2 2 2 0 Protein SLM4 DnaJ PF00226.31 EEQ36431.1 - 4.3e-23 81.2 0.5 1.4e-22 79.5 0.5 2.0 1 0 0 1 1 1 1 DnaJ domain Inhibitor_I34 PF10466.9 EEQ36431.1 - 1.3 9.7 7.9 0.52 11.0 0.2 2.9 2 1 0 2 2 2 0 Saccharopepsin inhibitor I34 PigN PF04987.14 EEQ36432.1 - 5.4e-134 447.5 50.1 8.5e-134 446.8 50.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EEQ36432.1 - 1.5e-10 41.2 0.5 1.1e-09 38.4 0.5 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EEQ36432.1 - 1e-06 28.4 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EEQ36432.1 - 0.00086 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily IGPS PF00218.21 EEQ36433.1 - 2.2e-74 249.9 0.1 2.9e-74 249.4 0.1 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 EEQ36433.1 - 1.2e-48 165.5 0.0 2e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EEQ36433.1 - 9.8e-07 28.7 0.3 3.2e-06 27.1 0.3 1.8 1 1 0 1 1 1 1 Peptidase C26 Peripla_BP_2 PF01497.18 EEQ36433.1 - 0.033 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein DUF4451 PF14616.6 EEQ36434.1 - 1.8e-30 105.6 1.4 4.1e-30 104.5 1.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) zf-Di19 PF05605.12 EEQ36434.1 - 0.28 11.5 6.3 2.1 8.7 0.1 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF2387 PF09526.10 EEQ36434.1 - 0.43 10.8 2.5 0.34 11.1 0.2 2.0 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Rep_fac-A_3 PF08661.11 EEQ36435.1 - 3.6e-20 72.3 0.1 4.1e-20 72.1 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1_2 PF15490.6 EEQ36435.1 - 0.00087 19.0 0.1 0.0013 18.4 0.1 1.3 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit Gar1 PF04410.14 EEQ36435.1 - 0.013 15.3 0.2 0.018 14.9 0.2 1.3 1 0 0 1 1 1 0 Gar1/Naf1 RNA binding region tRNA_anti-codon PF01336.25 EEQ36435.1 - 0.042 13.8 2.3 2.2 8.3 1.5 2.2 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain PFU PF09070.11 EEQ36436.1 - 1.3e-42 144.6 0.1 3.4e-42 143.3 0.1 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EEQ36436.1 - 2.1e-27 94.8 24.8 8.3e-06 26.4 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat PUL PF08324.11 EEQ36436.1 - 1.3e-20 73.8 1.5 2e-20 73.2 1.5 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.6 EEQ36436.1 - 0.014 15.4 0.0 0.074 13.1 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EEQ36436.1 - 0.017 13.8 3.4 0.76 8.3 0.1 3.2 2 1 1 3 3 3 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEQ36436.1 - 0.062 13.6 0.0 0.44 10.9 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EEQ36436.1 - 1.1 9.8 7.4 12 6.5 0.9 3.6 3 1 1 4 4 4 0 PQQ-like domain Syja_N PF02383.18 EEQ36438.1 - 5.7e-83 278.9 0.6 5.7e-83 278.9 0.6 1.5 2 0 0 2 2 2 1 SacI homology domain Multi-haem_cyto PF13447.6 EEQ36438.1 - 0.052 12.8 0.1 0.094 11.9 0.1 1.4 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH MFS_1 PF07690.16 EEQ36439.1 - 7.7e-32 110.6 12.4 7.7e-32 110.6 12.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Zip PF02535.22 EEQ36439.1 - 0.017 14.4 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter BNR_2 PF13088.6 EEQ36439.1 - 0.11 11.8 0.1 0.2 10.9 0.1 1.3 1 0 0 1 1 1 0 BNR repeat-like domain RNase_3_N PF18497.1 EEQ36440.1 - 3.3e-05 24.1 0.1 9.1e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain Ribonucleas_3_3 PF14622.6 EEQ36440.1 - 0.00045 20.4 0.0 0.00073 19.7 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EEQ36440.1 - 0.035 14.7 0.1 0.17 12.5 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease III domain Mito_carr PF00153.27 EEQ36441.1 - 5.4e-44 148.1 7.1 2e-17 62.9 0.3 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5437 PF17505.2 EEQ36442.1 - 0.028 14.4 0.3 0.47 10.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5437) IL12p40_C PF10420.9 EEQ36442.1 - 0.12 13.0 0.1 0.21 12.1 0.1 1.5 1 0 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus RNA_polI_A34 PF08208.11 EEQ36445.1 - 1.7e-28 100.2 21.2 2.4e-28 99.6 21.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 AP3D1 PF06375.11 EEQ36445.1 - 0.039 14.2 17.6 0.064 13.5 17.6 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Connexin PF00029.19 EEQ36445.1 - 3.7 7.2 7.3 4.5 7.0 7.3 1.2 1 0 0 1 1 1 0 Connexin RraA-like PF03737.15 EEQ36447.1 - 3e-32 111.9 2.8 3.7e-32 111.6 2.8 1.1 1 0 0 1 1 1 1 Aldolase/RraA Pkinase PF00069.25 EEQ36449.1 - 1.1e-71 241.3 0.0 1.3e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36449.1 - 1.1e-39 136.2 0.0 1.5e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ36449.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ36449.1 - 0.0085 15.1 0.1 0.012 14.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF1561 PF07598.11 EEQ36450.1 - 0.12 10.6 0.1 0.16 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1561) Cpta_toxin PF07254.12 EEQ36450.1 - 0.26 11.3 0.6 0.66 10.0 0.6 1.6 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system Pkinase PF00069.25 EEQ36451.1 - 4.6e-24 85.2 0.0 4.2e-23 82.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36451.1 - 6.3e-12 45.3 0.0 9.8e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ36451.1 - 0.058 12.7 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ36453.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36453.1 - 0.052 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.25 EEQ36454.1 - 6.2e-70 235.6 0.1 9.2e-70 235.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36454.1 - 1.4e-53 181.8 0.1 2.2e-53 181.2 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EEQ36454.1 - 5.2e-22 78.0 0.2 1.6e-21 76.4 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Haspin_kinase PF12330.8 EEQ36454.1 - 1.9e-08 33.7 2.8 3.8e-08 32.7 2.8 1.4 1 0 0 1 1 1 1 Haspin like kinase domain PH PF00169.29 EEQ36454.1 - 2.4e-07 31.2 0.0 5.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 EEQ36454.1 - 6.1e-07 28.6 2.2 3.9e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEQ36454.1 - 9.3e-07 28.4 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EEQ36454.1 - 0.0064 16.1 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EEQ36454.1 - 0.012 14.7 0.1 0.021 13.9 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EEQ36454.1 - 0.014 15.3 0.1 0.043 13.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.13 EEQ36454.1 - 0.052 13.5 23.0 0.083 12.9 23.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kdo PF06293.14 EEQ36454.1 - 0.098 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macoilin PF09726.9 EEQ36454.1 - 0.11 11.0 9.1 0.14 10.7 9.1 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 EEQ36454.1 - 7.1 6.1 7.6 15 5.1 7.6 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Gti1_Pac2 PF09729.9 EEQ36456.1 - 2.2e-46 158.2 2.7 3.6e-40 138.0 0.4 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family F-box-like PF12937.7 EEQ36457.1 - 2.2e-05 24.2 0.0 5.7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like TFA2_Winged_2 PF18121.1 EEQ36458.1 - 4.6e-21 74.3 0.1 1.3e-20 72.8 0.1 1.8 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EEQ36458.1 - 5.6e-19 68.2 0.2 1.4e-18 66.9 0.2 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain NTF2 PF02136.20 EEQ36459.1 - 2.5e-35 121.6 0.2 3.1e-35 121.3 0.2 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 EEQ36459.1 - 0.00052 19.3 0.3 0.0012 18.1 0.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) Aim21 PF11489.8 EEQ36461.1 - 2.2e-09 36.8 70.2 2.2e-09 36.8 70.2 3.7 1 1 2 3 3 3 1 Altered inheritance of mitochondria protein 21 cwf21 PF08312.12 EEQ36462.1 - 4.5e-14 52.3 8.9 4.5e-14 52.3 8.9 2.3 3 0 0 3 3 3 1 cwf21 domain Trans_reg_C PF00486.28 EEQ36462.1 - 0.0018 18.3 0.8 0.052 13.6 0.1 2.5 1 1 1 2 2 2 2 Transcriptional regulatory protein, C terminal Nop14 PF04147.12 EEQ36462.1 - 3.6 5.7 49.4 4.6 5.3 49.4 1.0 1 0 0 1 1 1 0 Nop14-like family His_Phos_2 PF00328.22 EEQ36463.1 - 7.7e-09 35.4 0.0 6.2e-05 22.5 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) EamA PF00892.20 EEQ36465.1 - 3.3e-28 98.6 33.1 1.7e-15 57.4 9.1 2.1 2 0 0 2 2 2 2 EamA-like transporter family DUF4336 PF14234.6 EEQ36466.1 - 2.7e-05 23.6 0.0 0.2 10.8 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) 4HBT PF03061.22 EEQ36467.1 - 4.1e-07 30.3 0.0 6.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Asn_synthase PF00733.21 EEQ36468.1 - 7.2e-19 68.6 2.4 2e-11 44.2 0.1 3.6 3 1 0 3 3 3 2 Asparagine synthase GATase_7 PF13537.6 EEQ36468.1 - 4.1e-11 42.9 0.0 1.2e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EEQ36468.1 - 2.2e-05 24.7 0.0 5.5e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EEQ36468.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Aluminium induced protein U3_snoRNA_assoc PF08297.11 EEQ36470.1 - 3.9e-17 62.7 4.3 3.9e-17 62.7 4.3 3.0 2 1 0 2 2 2 1 U3 snoRNA associated Tubulin_2 PF13809.6 EEQ36470.1 - 2.9 7.0 6.1 2.9 7.0 5.3 1.4 1 1 0 1 1 1 0 Tubulin like SOBP PF15279.6 EEQ36470.1 - 3.7 8.1 11.1 5.1 7.6 11.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein 2OG-FeII_Oxy PF03171.20 EEQ36471.1 - 3e-16 59.7 0.0 4.7e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EEQ36471.1 - 1.2e-12 48.6 0.3 2.7e-12 47.5 0.1 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal F-box-like PF12937.7 EEQ36472.1 - 8.3e-10 38.4 0.1 4.3e-09 36.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEQ36472.1 - 2.2e-09 37.0 1.7 2.7e-08 33.5 0.2 3.2 2 0 0 2 2 2 1 F-box domain TPR_2 PF07719.17 EEQ36472.1 - 6.3e-08 32.2 1.0 0.2 11.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ36472.1 - 1.4e-05 24.7 2.3 1.6 8.7 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ36472.1 - 0.0025 18.1 0.4 1.1 9.6 0.0 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ36472.1 - 0.0025 18.3 4.5 6.6 7.6 0.3 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ36472.1 - 0.046 13.9 1.5 2 8.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 EEQ36472.1 - 0.05 13.7 0.3 0.05 13.7 0.3 5.5 7 0 0 7 7 6 0 Leucine Rich repeat TPR_17 PF13431.6 EEQ36472.1 - 0.098 13.1 1.0 10 6.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat CRAL_TRIO_2 PF13716.6 EEQ36472.1 - 0.14 12.3 1.2 0.73 10.0 0.0 2.6 3 0 0 3 3 3 0 Divergent CRAL/TRIO domain TPR_14 PF13428.6 EEQ36472.1 - 0.14 13.0 0.1 98 4.2 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ36472.1 - 0.31 11.3 1.5 23 5.3 0.1 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Zip PF02535.22 EEQ36473.1 - 2.5e-21 76.3 5.6 2.5e-21 76.3 5.6 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter DUF3336 PF11815.8 EEQ36474.1 - 2.1e-35 121.4 1.7 4.9e-35 120.3 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EEQ36474.1 - 7.4e-20 72.0 0.0 1.5e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Lactamase_B_4 PF13691.6 EEQ36475.1 - 9e-26 89.3 0.1 1.8e-25 88.4 0.1 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EEQ36475.1 - 1.3e-06 28.1 0.0 0.0062 16.1 0.0 2.4 2 0 0 2 2 2 2 Beta-lactamase superfamily domain TPP1 PF10341.9 EEQ36476.1 - 4.4e-26 91.0 0.1 6.4e-26 90.5 0.1 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Alpha-E PF04168.12 EEQ36476.1 - 0.041 13.7 0.1 1.2 8.8 0.1 2.0 2 0 0 2 2 2 0 A predicted alpha-helical domain with a conserved ER motif. Herpes_LMP1 PF05297.11 EEQ36477.1 - 0.012 14.9 1.3 0.012 14.9 1.3 1.9 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Ribosomal_L2_C PF03947.18 EEQ36478.1 - 6.3e-51 171.8 4.1 1.5e-50 170.6 4.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EEQ36478.1 - 4e-24 84.4 0.5 1e-23 83.0 0.5 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain OSCP PF00213.18 EEQ36479.1 - 3.3e-47 160.8 2.4 3.8e-47 160.6 2.4 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit RRF PF01765.19 EEQ36479.1 - 0.033 14.2 1.9 0.65 9.9 0.0 2.8 2 1 1 3 3 3 0 Ribosome recycling factor AhpC-TSA PF00578.21 EEQ36481.1 - 1.4e-22 79.9 0.0 1.8e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEQ36481.1 - 8.1e-17 61.3 0.0 1.1e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin DUF2070 PF09843.9 EEQ36483.1 - 3 6.0 20.7 4 5.6 20.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TIG PF01833.24 EEQ36486.1 - 1.2e-10 41.3 0.5 1.2e-10 41.3 0.5 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.7 EEQ36486.1 - 7e-08 33.0 0.1 1.8e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ36486.1 - 1.1e-06 29.0 0.3 0.00088 19.8 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ36486.1 - 1.3e-05 25.1 0.1 0.059 13.9 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EEQ36486.1 - 1.4e-05 25.3 0.2 0.017 15.5 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EEQ36486.1 - 0.001 19.4 0.0 0.0028 18.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) HEM4 PF02602.15 EEQ36487.1 - 9.9e-48 162.5 0.0 1.1e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD AMP-binding PF00501.28 EEQ36488.1 - 6.2e-85 285.3 0.0 7.4e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ36488.1 - 1e-22 80.8 0.0 1.6e-21 77.0 0.1 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EEQ36488.1 - 1.3e-16 60.3 0.1 2.9e-16 59.1 0.1 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus DUF1967 PF09269.11 EEQ36488.1 - 0.16 12.0 0.1 0.55 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) AAA_lid_9 PF17871.1 EEQ36490.1 - 2.9e-21 75.3 2.3 6.3e-21 74.3 2.3 1.6 1 0 0 1 1 1 1 AAA lid domain Phage_GP20 PF06810.11 EEQ36490.1 - 0.11 12.4 0.9 0.2 11.4 0.9 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Clp_N PF02861.20 EEQ36490.1 - 0.11 12.6 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 Clp amino terminal domain, pathogenicity island component OPA3 PF07047.12 EEQ36491.1 - 4.1e-44 149.4 0.8 5.4e-44 149.0 0.8 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Med11 PF10280.9 EEQ36491.1 - 0.067 13.7 0.1 0.091 13.2 0.1 1.2 1 0 0 1 1 1 0 Mediator complex protein DUF1479 PF07350.12 EEQ36491.1 - 0.16 10.7 0.3 0.29 9.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Histone PF00125.24 EEQ36492.1 - 2.4e-17 63.6 0.0 2.7e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EEQ36492.1 - 4.3e-13 48.7 0.6 9.1e-13 47.7 0.3 1.7 2 0 0 2 2 2 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EEQ36492.1 - 0.00098 19.4 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 EEQ36492.1 - 0.034 14.2 0.1 0.61 10.2 0.0 2.1 2 0 0 2 2 2 0 hTAFII28-like protein conserved region NPR2 PF06218.11 EEQ36493.1 - 6.2e-184 611.8 0.8 8.6e-184 611.4 0.8 1.2 1 0 0 1 1 1 1 Nitrogen permease regulator 2 Cwf_Cwc_15 PF04889.12 EEQ36493.1 - 0.023 14.4 8.3 0.038 13.7 8.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zn_clus PF00172.18 EEQ36494.1 - 3.1e-10 40.0 13.7 5.3e-10 39.3 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cpn60_TCP1 PF00118.24 EEQ36495.1 - 1.3e-82 278.1 13.8 3.5e-82 276.6 13.8 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rrf2 PF02082.20 EEQ36495.1 - 0.012 15.9 0.1 0.033 14.5 0.1 1.8 1 0 0 1 1 1 0 Transcriptional regulator RNA_pol_I_TF PF04090.12 EEQ36497.1 - 5.4e-50 169.7 1.6 1.2e-49 168.5 1.6 1.5 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor zf-BED PF02892.15 EEQ36497.1 - 0.012 15.6 0.5 0.032 14.2 0.5 1.7 1 0 0 1 1 1 0 BED zinc finger zf-rbx1 PF12678.7 EEQ36498.1 - 2.6e-09 37.2 3.8 4.6e-09 36.4 3.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ36498.1 - 2.3e-08 34.3 7.5 6.8e-08 32.7 7.5 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ36498.1 - 6.3e-05 22.8 3.9 0.00011 22.1 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ36498.1 - 0.00013 21.9 2.5 0.00081 19.3 3.1 1.9 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ36498.1 - 0.00042 20.1 3.0 0.0013 18.5 3.2 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EEQ36498.1 - 0.00045 20.2 2.7 0.0009 19.2 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEQ36498.1 - 0.00079 19.2 6.0 0.0011 18.8 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEQ36498.1 - 0.0012 18.4 0.3 0.0012 18.4 0.3 1.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EEQ36498.1 - 0.0024 17.7 6.9 0.037 13.9 6.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEQ36498.1 - 0.0038 17.2 2.8 0.011 15.8 2.8 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EEQ36498.1 - 0.016 15.4 1.4 0.051 13.8 1.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 EEQ36498.1 - 0.056 13.7 0.9 0.13 12.5 0.3 1.7 1 1 1 2 2 2 0 Zinc-ribbon like family zf-C3HC4_4 PF15227.6 EEQ36498.1 - 0.081 13.1 1.4 0.23 11.6 0.3 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Apolipoprotein PF01442.18 EEQ36499.1 - 7.3e-08 32.5 31.0 0.0014 18.6 15.0 3.9 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EEQ36499.1 - 2.7e-06 27.5 40.1 0.24 11.4 3.8 5.0 1 1 4 5 5 5 4 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4201 PF13870.6 EEQ36499.1 - 0.00029 20.6 12.2 0.00029 20.6 12.2 3.8 2 1 1 4 4 4 1 Domain of unknown function (DUF4201) AAA_13 PF13166.6 EEQ36499.1 - 0.00053 18.8 12.6 0.00053 18.8 12.6 2.3 2 1 0 2 2 2 1 AAA domain CEP63 PF17045.5 EEQ36499.1 - 0.0014 18.6 38.6 0.0054 16.7 24.4 3.2 2 1 1 3 3 3 1 Centrosomal protein of 63 kDa DUF3584 PF12128.8 EEQ36499.1 - 0.0039 14.8 32.0 0.024 12.2 14.4 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) DUF4407 PF14362.6 EEQ36499.1 - 0.0053 16.2 22.0 0.017 14.5 5.5 3.1 2 2 0 2 2 2 1 Domain of unknown function (DUF4407) ADIP PF11559.8 EEQ36499.1 - 0.0067 16.5 10.0 0.0067 16.5 10.0 4.4 1 1 2 4 4 4 1 Afadin- and alpha -actinin-Binding Spc29 PF17082.5 EEQ36499.1 - 0.0074 16.2 4.9 0.0074 16.2 4.9 3.5 1 1 1 3 3 3 1 Spindle Pole Component 29 Filament PF00038.21 EEQ36499.1 - 0.033 13.8 38.5 0.64 9.5 12.3 4.3 1 1 1 3 3 3 0 Intermediate filament protein Atg14 PF10186.9 EEQ36499.1 - 0.071 12.2 36.6 0.11 11.5 17.4 2.7 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMMR_N PF15905.5 EEQ36499.1 - 0.11 11.9 43.6 0.13 11.7 14.2 4.0 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Hairy_orange PF07527.13 EEQ36499.1 - 0.14 12.4 0.0 16 5.8 0.0 2.8 2 0 0 2 2 2 0 Hairy Orange MADF_DNA_bdg PF10545.9 EEQ36499.1 - 0.14 12.5 1.4 3.5 8.0 0.0 3.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HrpB7 PF09486.10 EEQ36499.1 - 0.16 12.3 8.2 0.89 9.9 0.1 4.2 2 2 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) HALZ PF02183.18 EEQ36499.1 - 0.18 12.1 7.4 8.3 6.7 0.1 4.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1664 PF07889.12 EEQ36499.1 - 0.62 10.1 33.5 0.59 10.2 8.4 5.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EEQ36499.1 - 0.8 10.2 30.2 0.12 12.9 1.1 6.0 2 2 3 5 5 4 0 Nucleopolyhedrovirus P10 protein DUF4106 PF13388.6 EEQ36499.1 - 2.4 7.3 9.9 0.28 10.4 5.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) DUF3782 PF12644.7 EEQ36499.1 - 2.4 8.4 9.1 0.37 11.0 0.2 3.9 5 0 0 5 5 4 0 Protein of unknown function (DUF3782) DUF465 PF04325.13 EEQ36499.1 - 2.7 8.1 6.3 0.44 10.6 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF465) DUF730 PF05325.11 EEQ36499.1 - 3.1 7.8 7.2 0.64 10.0 1.4 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF730) Spore_III_AB PF09548.10 EEQ36499.1 - 3.2 7.9 17.4 7.3 6.7 2.8 4.0 2 1 2 4 4 4 0 Stage III sporulation protein AB (spore_III_AB) Exonuc_VII_L PF02601.15 EEQ36499.1 - 3.2 7.2 36.0 0.62 9.6 6.1 3.6 1 1 1 2 2 1 0 Exonuclease VII, large subunit HisKA PF00512.25 EEQ36499.1 - 3.3 7.8 6.7 2.1 8.4 0.6 3.3 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain FPP PF05911.11 EEQ36499.1 - 4.8 5.3 48.0 2.2 6.3 22.9 2.1 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil OmpH PF03938.14 EEQ36499.1 - 5 7.5 31.0 1.5 9.1 9.6 4.7 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 EEQ36499.1 - 5.4 7.4 36.4 0.085 13.3 16.2 3.2 1 1 0 2 2 2 0 Fez1 Kinesin PF00225.23 EEQ36500.1 - 1.3e-95 320.1 0.0 1.6e-95 319.8 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ36500.1 - 1.2e-19 70.7 0.0 2.3e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding dsDNA_bind PF01984.20 EEQ36501.1 - 1.1e-24 86.8 5.5 8e-24 84.1 5.5 1.8 1 1 0 1 1 1 1 Double-stranded DNA-binding domain DUF3192 PF11399.8 EEQ36501.1 - 0.069 13.1 0.1 0.097 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Ras PF00071.22 EEQ36502.1 - 2.8e-44 150.6 0.2 3.2e-44 150.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ36502.1 - 1.9e-26 92.6 0.1 3e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ36502.1 - 2.7e-08 33.4 0.1 3.2e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ36502.1 - 0.0042 16.6 0.1 0.0056 16.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TIR_2 PF13676.6 EEQ36502.1 - 0.02 15.5 0.1 0.03 14.9 0.1 1.3 1 0 0 1 1 1 0 TIR domain TetR_C_16 PF17920.1 EEQ36502.1 - 0.096 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-C2H2 PF00096.26 EEQ36504.1 - 4.9e-11 42.4 14.6 4e-05 23.8 3.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ36504.1 - 2.1e-08 34.2 5.7 2.1e-08 34.2 5.7 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ36504.1 - 2e-07 31.2 12.7 9.6e-05 22.9 2.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Ogr_Delta PF04606.12 EEQ36504.1 - 0.0005 20.0 0.7 0.033 14.2 0.0 2.3 2 0 0 2 2 2 1 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.6 EEQ36504.1 - 0.00065 19.6 1.3 0.00065 19.6 1.3 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 EEQ36504.1 - 0.0033 17.7 1.1 0.0033 17.7 1.1 2.2 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-LYAR PF08790.11 EEQ36504.1 - 0.0093 15.9 2.2 0.19 11.7 0.5 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 EEQ36504.1 - 0.012 15.9 4.5 0.024 14.9 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 EEQ36504.1 - 0.049 13.5 1.9 0.085 12.7 1.9 1.4 1 0 0 1 1 1 0 GAGA factor zf-C2HE PF16278.5 EEQ36504.1 - 0.41 11.1 3.3 0.79 10.2 3.3 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 EEQ36504.1 - 0.52 11.0 3.3 16 6.2 0.1 2.3 2 0 0 2 2 2 0 FOXP coiled-coil domain zf_C2H2_ZHX PF18387.1 EEQ36504.1 - 0.94 9.2 6.9 1.5 8.5 1.1 2.2 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 EEQ36504.1 - 2.6 8.6 5.8 2.2 8.8 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EEQ36504.1 - 4.9 7.2 7.3 6.6 6.8 0.6 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type GAD PF02938.14 EEQ36506.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 GAD domain Metallophos PF00149.28 EEQ36507.1 - 9.6e-36 124.2 0.1 3.1e-35 122.5 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEQ36507.1 - 1.6e-18 66.8 0.3 3.4e-18 65.8 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Acetyltransf_1 PF00583.25 EEQ36508.1 - 1.2e-08 35.2 0.0 1.9e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ36508.1 - 1.9e-06 28.2 0.0 3.6e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ36508.1 - 0.00029 20.8 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EEQ36508.1 - 0.0039 17.3 0.0 0.0075 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ36508.1 - 0.009 16.0 0.0 0.026 14.5 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 EEQ36508.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Methyltransf_28 PF02636.17 EEQ36509.1 - 5.8e-77 258.9 0.0 7.9e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 EEQ36509.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Herpes_capsid PF06112.11 EEQ36509.1 - 0.76 9.8 7.5 1.5 8.9 7.5 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1674 PF07896.12 EEQ36510.1 - 6.9e-19 68.1 2.3 1.5e-18 67.0 2.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) CcdA PF07362.12 EEQ36510.1 - 0.095 13.1 0.1 0.15 12.5 0.1 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Methyltransf_16 PF10294.9 EEQ36511.1 - 3.9e-16 59.3 0.0 8.4e-16 58.2 0.0 1.5 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EEQ36511.1 - 1.8e-06 27.9 0.0 4e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Aminotran_1_2 PF00155.21 EEQ36512.1 - 2.9e-70 237.2 0.0 3.4e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ36512.1 - 0.0004 19.4 0.0 0.00089 18.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EEQ36512.1 - 0.0023 16.5 0.0 0.0053 15.3 0.0 1.6 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 EEQ36512.1 - 0.065 11.8 0.0 0.095 11.2 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Beta_elim_lyase PF01212.21 EEQ36512.1 - 0.24 10.6 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase CybS PF05328.12 EEQ36513.1 - 1.8e-51 173.3 0.1 2e-51 173.1 0.1 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit PPP4R2 PF09184.11 EEQ36515.1 - 2.3e-05 24.2 6.8 4.6e-05 23.1 6.8 1.6 1 1 0 1 1 1 1 PPP4R2 Ribosomal_S7 PF00177.21 EEQ36516.1 - 4.7e-32 110.7 0.0 8.3e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DUF3371 PF11851.8 EEQ36518.1 - 0.0074 17.4 0.6 0.014 16.5 0.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3371) Peptidase_M16_C PF05193.21 EEQ36519.1 - 2.7e-19 69.9 0.3 1.4e-18 67.5 0.1 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEQ36519.1 - 6.4e-12 45.7 0.5 9.5e-10 38.6 0.5 2.5 1 1 0 1 1 1 1 Insulinase (Peptidase family M16) Baculo_PEP_C PF04513.12 EEQ36519.1 - 1.7 8.7 4.1 0.49 10.4 0.3 2.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus G-alpha PF00503.20 EEQ36521.1 - 8.3e-99 331.1 0.0 1e-98 330.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EEQ36521.1 - 1.5e-13 50.5 0.4 6.8e-09 35.4 0.0 3.4 2 2 1 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ36521.1 - 0.00074 18.9 0.2 0.0054 16.1 0.0 2.1 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEQ36521.1 - 0.012 15.2 0.0 0.14 11.7 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF4888 PF16229.5 EEQ36521.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4888) NB-ARC PF00931.22 EEQ36521.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EEQ36521.1 - 0.17 11.7 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EEQ36521.1 - 0.2 11.8 0.0 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Metallophos PF00149.28 EEQ36522.1 - 1.9e-11 44.9 0.2 3.2e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PgaD PF13994.6 EEQ36522.1 - 0.038 14.1 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 PgaD-like protein DnaJ PF00226.31 EEQ36522.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 DnaJ domain DUF572 PF04502.13 EEQ36525.1 - 1.7e-55 188.9 16.6 2.7e-54 185.0 16.2 1.9 1 1 0 1 1 1 1 Family of unknown function (DUF572) DUF4358 PF14270.6 EEQ36525.1 - 0.02 15.2 3.8 3.2 8.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) Vps23_core PF09454.10 EEQ36525.1 - 0.34 10.9 1.6 1.8 8.6 0.2 2.3 2 0 0 2 2 2 0 Vps23 core domain Sec6 PF06046.13 EEQ36526.1 - 9.1e-170 565.8 9.0 1.5e-169 565.1 9.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Mating_N PF12731.7 EEQ36526.1 - 0.0052 16.8 1.2 0.07 13.2 0.1 3.1 2 0 0 2 2 2 1 Mating-type protein beta 1 Casein PF00363.18 EEQ36526.1 - 0.15 12.4 0.7 6 7.3 0.1 2.7 2 0 0 2 2 2 0 Casein BLOC1_2 PF10046.9 EEQ36526.1 - 0.34 11.3 6.6 8.7 6.7 0.1 3.3 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rootletin PF15035.6 EEQ36526.1 - 0.7 9.9 4.5 1.2 9.1 0.8 2.5 1 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion COG5 PF10392.9 EEQ36526.1 - 1.2 9.3 7.9 5.1 7.3 3.5 3.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF16 PF01519.16 EEQ36526.1 - 4 8.0 10.2 17 5.9 4.8 3.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Stathmin PF00836.19 EEQ36526.1 - 4.1 7.4 6.1 3.1 7.8 0.9 2.4 2 0 0 2 2 2 0 Stathmin family LsmAD PF06741.13 EEQ36527.1 - 1.5e-28 99.2 1.0 3.9e-28 97.8 1.0 1.8 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 EEQ36527.1 - 1.2e-14 54.1 0.0 7.7e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 Ataxin 2 SM domain PAM2 PF07145.15 EEQ36527.1 - 0.24 11.2 2.1 0.8 9.5 2.1 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region FAM176 PF14851.6 EEQ36527.1 - 2.2 8.0 3.9 0.79 9.4 0.4 2.1 2 0 0 2 2 2 0 FAM176 family DUF4692 PF15763.5 EEQ36527.1 - 3.9 7.9 0.0 3.9 7.9 0.0 3.6 4 1 1 5 5 5 0 Regulator of human erythroid cell expansion (RHEX) DUF2347 PF09804.9 EEQ36528.1 - 7.8e-61 206.1 0.0 7.3e-42 143.9 0.0 2.4 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EEQ36528.1 - 8.6e-11 42.3 30.4 1.7e-05 25.0 0.1 4.8 3 1 2 5 5 5 3 Domain of unknown function (DUF4484) Trypan_PARP PF05887.11 EEQ36528.1 - 0.42 10.6 13.9 0.94 9.5 13.9 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF202 PF02656.15 EEQ36529.1 - 9.7e-16 58.0 3.1 9.7e-16 58.0 3.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) UPF0715 PF17094.5 EEQ36529.1 - 0.0054 17.3 0.4 0.0082 16.7 0.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0715) Gpr1_Fun34_YaaH PF01184.19 EEQ36530.1 - 3.3e-85 284.9 24.0 3.8e-85 284.7 24.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family P5-ATPase PF12409.8 EEQ36531.1 - 1.9e-37 128.2 0.0 6.3e-37 126.5 0.0 2.0 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EEQ36531.1 - 7.1e-32 110.4 0.0 3e-31 108.3 0.0 2.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ36531.1 - 3.6e-17 63.4 0.0 7.3e-08 32.9 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ36531.1 - 3.3e-05 23.9 0.0 7.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EEQ36531.1 - 0.03 14.0 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ36531.1 - 0.14 11.8 0.0 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TAFII55_N PF04658.13 EEQ36532.1 - 2e-37 128.4 0.3 2e-37 128.4 0.3 2.7 2 1 0 2 2 2 1 TAFII55 protein conserved region Pribosyl_synth PF14572.6 EEQ36533.1 - 2.5e-42 145.0 2.8 2.9e-36 125.2 1.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EEQ36533.1 - 3e-39 133.6 0.4 9.7e-39 131.9 0.0 2.0 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EEQ36533.1 - 7e-17 61.4 1.6 1.6e-16 60.2 1.2 1.7 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEQ36533.1 - 0.0021 17.6 0.2 0.0035 16.8 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ISPD_C PF18706.1 EEQ36533.1 - 0.1 12.2 0.5 0.17 11.5 0.5 1.3 1 0 0 1 1 1 0 D-ribitol-5-phosphate cytidylyltransferase C-terminal domain Chlorosome_CsmC PF11098.8 EEQ36533.1 - 0.18 11.8 2.0 0.36 10.8 2.0 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C HAD_2 PF13419.6 EEQ36534.1 - 8.5e-16 58.5 0.0 1.3e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ36534.1 - 2.3e-09 37.8 0.0 5.6e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EEQ36534.1 - 9.9e-06 25.6 0.0 3.6e-05 23.8 0.0 2.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ36534.1 - 0.011 16.2 0.0 0.018 15.5 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase BRAP2 PF07576.12 EEQ36535.1 - 4.3e-30 103.8 0.0 9.2e-30 102.8 0.0 1.6 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EEQ36535.1 - 7.2e-20 71.1 5.7 1.8e-19 69.8 5.7 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EEQ36535.1 - 5.1e-08 33.1 10.2 5.1e-08 33.1 10.2 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ36535.1 - 1.4e-06 28.0 9.9 3.7e-06 26.7 9.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ36535.1 - 1.4e-05 25.0 7.0 0.00013 21.9 7.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EEQ36535.1 - 0.0001 21.9 4.8 0.00028 20.6 4.8 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EEQ36535.1 - 0.00011 22.1 7.5 0.00011 22.1 7.5 2.2 2 1 1 3 3 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 EEQ36535.1 - 0.00015 21.9 6.4 0.00015 21.9 6.4 2.5 2 1 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EEQ36535.1 - 0.0002 21.2 6.2 0.0002 21.2 6.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ36535.1 - 0.00042 20.1 9.4 0.00042 20.1 9.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEQ36535.1 - 0.016 15.2 3.9 0.042 13.9 3.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DivIC PF04977.15 EEQ36535.1 - 0.024 14.4 2.2 0.024 14.4 2.2 3.3 2 1 0 3 3 3 0 Septum formation initiator MbeD_MobD PF04899.12 EEQ36535.1 - 0.027 14.6 5.4 0.24 11.5 0.1 3.4 3 0 0 3 3 3 0 MbeD/MobD like ZapB PF06005.12 EEQ36535.1 - 0.029 14.8 6.3 0.029 14.8 6.3 3.4 2 1 1 3 3 3 0 Cell division protein ZapB DUF4201 PF13870.6 EEQ36535.1 - 0.32 10.7 13.1 0.022 14.5 7.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) zf-RING_4 PF14570.6 EEQ36535.1 - 0.36 10.7 7.9 0.86 9.5 7.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF16 PF01519.16 EEQ36535.1 - 0.43 11.1 9.7 0.89 10.1 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function DUF16 Spc7 PF08317.11 EEQ36535.1 - 1.8 7.3 14.9 0.042 12.7 7.6 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein bZIP_1 PF00170.21 EEQ36535.1 - 2.9 8.1 18.0 0.11 12.6 3.4 2.9 2 1 0 3 3 2 0 bZIP transcription factor Prok-RING_4 PF14447.6 EEQ36535.1 - 5.4 7.0 23.0 0.051 13.5 6.9 3.2 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 YabA PF06156.13 EEQ36535.1 - 5.6 7.7 14.0 1 10.0 3.3 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Zn_ribbon_17 PF17120.5 EEQ36535.1 - 6.6 6.4 14.7 0.43 10.2 4.8 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type S1 PF00575.23 EEQ36536.1 - 8e-61 202.3 26.5 9.6e-17 61.1 0.4 12.6 12 1 1 13 13 13 8 S1 RNA binding domain TPR_19 PF14559.6 EEQ36536.1 - 5e-07 30.1 0.0 0.027 15.0 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36536.1 - 3e-05 24.5 0.1 11 7.1 0.0 4.4 2 1 2 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 EEQ36536.1 - 4.7e-05 23.5 0.1 4.7e-05 23.5 0.1 3.0 3 1 2 5 5 5 1 Suppressor of forked protein (Suf) S1_2 PF13509.6 EEQ36536.1 - 0.0035 17.4 1.1 15 5.7 0.0 5.7 6 0 0 6 6 6 1 S1 domain TPR_15 PF13429.6 EEQ36536.1 - 0.015 14.5 2.2 2.7 7.1 0.4 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EEQ36536.1 - 0.018 15.0 0.2 3.3 7.7 0.0 4.5 5 1 0 5 5 5 0 RNase II-type exonuclease C-terminal S1 domain SDA1 PF05285.12 EEQ36536.1 - 0.14 11.5 22.6 0.07 12.6 17.2 2.3 2 0 0 2 2 2 0 SDA1 ProQ_C PF17516.2 EEQ36536.1 - 1.8 8.0 7.8 16 5.0 0.1 4.8 6 0 0 6 6 6 0 ProQ C-terminal domain BUD22 PF09073.10 EEQ36536.1 - 1.9 7.8 27.4 3.8 6.7 23.2 2.3 2 0 0 2 2 2 0 BUD22 Nexin_C PF08628.12 EEQ36537.1 - 4.8e-23 81.9 0.2 7e-23 81.3 0.2 1.3 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 EEQ36538.1 - 7.9e-18 64.5 0.6 2.1e-17 63.1 0.6 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EEQ36538.1 - 0.00036 20.8 0.4 0.00036 20.8 0.4 3.2 3 1 0 3 3 3 1 Regulator of G protein signaling domain YliH PF10799.8 EEQ36538.1 - 0.026 14.4 0.4 0.073 13.0 0.4 1.7 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) DUF2155 PF09923.9 EEQ36538.1 - 0.066 13.5 0.1 0.19 12.0 0.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2155) PXA PF02194.15 EEQ36539.1 - 2.2e-40 138.6 0.7 2.8e-40 138.2 0.7 1.1 1 0 0 1 1 1 1 PXA domain G-patch PF01585.23 EEQ36540.1 - 0.0091 15.9 1.3 0.058 13.3 1.3 2.5 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEQ36540.1 - 0.14 12.3 0.6 0.14 12.3 0.6 5.2 2 1 0 2 2 2 0 G-patch domain Asp-B-Hydro_N PF05279.11 EEQ36540.1 - 5.2 7.1 47.7 7.1 6.6 47.7 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2744 PF10910.8 EEQ36541.1 - 0.046 13.7 0.1 0.099 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2744) DUF2433 PF10360.9 EEQ36541.1 - 0.11 12.6 0.5 1.2 9.2 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2433) Retrotrans_gag PF03732.17 EEQ36541.1 - 0.36 11.1 3.1 2.2 8.6 1.8 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein RRM_1 PF00076.22 EEQ36542.1 - 1.8e-28 98.2 1.3 7.5e-14 51.3 0.2 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ36542.1 - 4.4e-23 80.9 0.1 2.2e-21 75.5 0.0 2.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EEQ36542.1 - 0.027 14.1 0.1 0.25 10.9 0.1 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA-synt_1 PF00133.22 EEQ36543.1 - 2.2e-39 135.2 0.1 1.4e-29 102.8 0.0 2.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EEQ36543.1 - 9.3e-21 74.0 0.2 3.1e-09 36.1 0.0 4.2 3 1 1 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEQ36543.1 - 8.7e-13 48.5 0.1 2.7e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EEQ36543.1 - 5.6e-06 25.9 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EEQ36543.1 - 0.059 12.9 0.2 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Leucyl-tRNA synthetase, Domain 2 WD40 PF00400.32 EEQ36544.1 - 4.4e-36 122.3 21.9 6.7e-06 26.7 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EEQ36544.1 - 4.8e-11 42.4 1.8 9.8e-11 41.4 1.8 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ36544.1 - 4.1e-10 39.3 1.3 4.1e-10 39.3 1.3 2.3 2 0 0 2 2 2 1 F-box domain CDC4_D PF16856.5 EEQ36544.1 - 7.7e-10 38.5 0.2 1.7e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain ANAPC4_WD40 PF12894.7 EEQ36544.1 - 0.0001 22.5 0.2 2.3 8.6 0.0 4.3 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ36544.1 - 0.0018 17.0 1.4 2.5 6.7 0.2 3.5 4 0 0 4 4 4 2 Nucleoporin Nup120/160 PRANC PF09372.10 EEQ36544.1 - 0.029 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 PRANC domain F-box_4 PF15966.5 EEQ36544.1 - 0.035 14.0 0.6 0.092 12.6 0.3 1.9 2 0 0 2 2 2 0 F-box WD40_like PF17005.5 EEQ36544.1 - 0.053 12.8 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain PQQ_2 PF13360.6 EEQ36544.1 - 0.058 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain Arylsulfotran_2 PF14269.6 EEQ36544.1 - 0.078 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 Arylsulfotransferase (ASST) zf-C3HC PF07967.13 EEQ36545.1 - 1.7e-26 92.8 4.2 2.4e-25 89.1 0.5 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like YycH PF07435.11 EEQ36545.1 - 0.055 12.4 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 YycH protein Rsm1 PF08600.10 EEQ36545.1 - 0.28 11.3 2.3 0.35 11.0 0.1 2.2 2 0 0 2 2 2 0 Rsm1-like zinc_ribbon_10 PF10058.9 EEQ36545.1 - 1.1 9.1 4.3 4.3 7.2 0.1 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein VWA PF00092.28 EEQ36546.1 - 0.014 15.6 0.1 0.48 10.7 0.0 2.1 1 1 1 2 2 2 0 von Willebrand factor type A domain VWA_2 PF13519.6 EEQ36546.1 - 0.089 13.5 0.0 0.98 10.1 0.0 2.2 1 1 0 1 1 1 0 von Willebrand factor type A domain SRP19 PF01922.17 EEQ36547.1 - 1.3e-31 109.4 0.0 2.4e-31 108.5 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.27 EEQ36548.1 - 4.8e-19 68.4 0.1 6.5e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RRN9 PF10680.9 EEQ36549.1 - 0.00012 22.2 6.3 0.079 13.2 0.6 3.0 1 1 1 2 2 2 2 RNA polymerase I specific transcription initiation factor Cyt-b5 PF00173.28 EEQ36550.1 - 4.6e-21 74.7 2.5 8.9e-21 73.8 0.1 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EEQ36550.1 - 1.4e-12 48.1 20.3 1.4e-12 48.1 20.3 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily COX14 PF14880.6 EEQ36550.1 - 0.37 10.7 2.6 6.2 6.7 0.8 2.5 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Zds_C PF08632.10 EEQ36551.1 - 5e-31 106.2 1.7 9.2e-31 105.4 1.7 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CPBP PF02517.16 EEQ36552.1 - 2.2e-13 50.4 2.7 2.2e-13 50.4 2.7 2.1 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease DUF3270 PF11674.8 EEQ36552.1 - 9.7 6.5 6.5 13 6.0 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) Aconitase PF00330.20 EEQ36553.1 - 2.9e-112 376.0 0.0 3.1e-111 372.6 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEQ36553.1 - 1.2e-31 109.8 0.0 2.1e-31 109.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EEQ36553.1 - 0.062 12.0 0.0 0.098 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Fungal_trans_2 PF11951.8 EEQ36554.1 - 2.9e-57 194.2 0.2 3.9e-57 193.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ36554.1 - 0.0022 18.1 4.8 0.0033 17.5 3.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.21 EEQ36555.1 - 6.8e-92 308.5 43.5 8e-92 308.3 43.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ36555.1 - 1.4e-23 83.4 48.3 4.8e-23 81.7 48.8 1.6 1 1 1 2 2 2 1 Amino acid permease Peptidase_M19 PF01244.21 EEQ36556.1 - 6.1e-108 360.7 0.0 7.2e-108 360.5 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 EEQ36556.1 - 0.0067 16.3 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase TIP120 PF08623.10 EEQ36557.1 - 6.2e-21 74.9 6.2 1.6e-20 73.5 0.2 4.1 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.6 EEQ36557.1 - 0.0017 18.7 0.9 0.31 11.5 0.1 3.9 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EEQ36557.1 - 0.0041 17.2 0.1 3.1 8.3 0.0 4.7 4 1 1 5 5 5 1 HEAT repeat Ribosomal_S8 PF00410.19 EEQ36557.1 - 0.032 14.2 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 Ribosomal protein S8 CBF PF03914.17 EEQ36557.1 - 5.2 7.1 11.7 1.7 8.6 0.3 4.5 4 3 0 4 4 4 0 CBF/Mak21 family DUF2373 PF10180.9 EEQ36558.1 - 2.1e-22 78.7 0.7 4.2e-22 77.8 0.7 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) BUD22 PF09073.10 EEQ36558.1 - 0.18 11.1 66.2 0.0053 16.2 56.5 2.0 2 0 0 2 2 2 0 BUD22 M20_dimer PF07687.14 EEQ36559.1 - 5.3e-21 74.6 0.0 1e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EEQ36559.1 - 2e-20 73.4 0.2 2.7e-19 69.7 0.2 2.0 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EEQ36559.1 - 0.0052 16.5 0.0 0.0078 15.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 YuiB PF14068.6 EEQ36559.1 - 0.087 13.4 0.0 0.31 11.6 0.0 2.0 2 0 0 2 2 2 0 Putative membrane protein Med28 PF11594.8 EEQ36560.1 - 0.00072 19.6 0.5 0.00086 19.4 0.5 1.1 1 0 0 1 1 1 1 Mediator complex subunit 28 DegS PF05384.11 EEQ36560.1 - 0.0063 16.0 0.5 0.0083 15.6 0.5 1.2 1 0 0 1 1 1 1 Sensor protein DegS DUF4290 PF14123.6 EEQ36560.1 - 0.0097 15.5 0.2 0.0098 15.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4290) DUF3552 PF12072.8 EEQ36561.1 - 0.0052 16.2 0.0 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3552) Tropomyosin PF00261.20 EEQ36561.1 - 0.13 11.6 0.0 0.36 10.1 0.0 1.5 1 1 0 1 1 1 0 Tropomyosin HAD PF12710.7 EEQ36562.1 - 8.2e-15 55.7 0.7 1.4e-14 54.9 0.7 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EEQ36562.1 - 1.8e-07 30.8 0.0 8.6e-05 22.0 0.0 2.8 2 1 0 2 2 2 2 Putative Phosphatase UMPH-1 PF05822.12 EEQ36562.1 - 0.00026 20.6 0.0 0.0004 20.0 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 EEQ36562.1 - 0.0089 16.3 0.4 0.018 15.3 0.4 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase XkdW PF09636.10 EEQ36562.1 - 0.011 15.8 0.0 0.65 10.1 0.0 2.1 2 0 0 2 2 2 0 XkdW protein TPR_1 PF00515.28 EEQ36563.1 - 6.4e-11 41.6 2.6 0.0027 17.5 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ36563.1 - 7.3e-10 38.2 22.0 0.003 17.5 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ36563.1 - 1e-07 31.4 12.8 0.0074 15.5 1.0 5.0 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ36563.1 - 1.1e-05 25.0 8.3 0.01 15.5 0.2 5.0 5 0 0 5 5 5 1 TPR repeat TPR_14 PF13428.6 EEQ36563.1 - 3.5e-05 24.3 41.9 0.075 13.9 0.4 9.0 6 3 4 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ36563.1 - 6.1e-05 23.1 16.6 0.71 10.1 5.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ36563.1 - 6.9e-05 23.3 28.4 0.011 16.2 5.2 6.5 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ36563.1 - 0.00028 21.4 40.0 0.11 13.1 0.4 7.8 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ36563.1 - 0.00043 20.5 0.3 0.00043 20.5 0.3 6.5 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ36563.1 - 0.00066 19.7 5.6 4.3 7.8 0.1 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ36563.1 - 0.0035 17.6 5.6 2.1 8.9 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 EEQ36563.1 - 2.8 8.4 9.5 2.6 8.4 5.4 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat MMR_HSR1 PF01926.23 EEQ36564.1 - 4.6e-05 23.5 0.0 0.00022 21.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EEQ36564.1 - 0.0075 16.3 0.0 0.018 15.1 0.0 1.6 1 1 0 1 1 1 1 Dynamin family GTP_EFTU PF00009.27 EEQ36564.1 - 0.012 15.2 0.2 0.12 12.0 0.0 2.5 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain MobB PF03205.14 EEQ36564.1 - 0.046 13.6 0.0 0.72 9.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EEQ36564.1 - 0.053 13.8 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EEQ36564.1 - 0.055 13.4 0.0 0.83 9.5 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EEQ36564.1 - 0.055 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.29 EEQ36566.1 - 4.2e-35 121.1 0.1 8.4e-35 120.1 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ36566.1 - 5e-27 94.4 0.0 1.2e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ36566.1 - 4.2e-06 26.9 0.0 7.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EEQ36566.1 - 0.0022 17.7 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ36566.1 - 0.021 15.1 0.4 0.43 10.8 0.1 2.6 2 1 0 2 2 2 0 AAA domain Sod_Fe_C PF02777.18 EEQ36567.1 - 1.5e-13 50.7 0.1 8.4e-07 29.1 0.0 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain DUF5474 PF17568.2 EEQ36567.1 - 0.018 15.1 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5474) Pal1 PF08316.11 EEQ36568.1 - 1.9e-50 171.2 1.6 1.9e-50 171.2 1.6 2.1 2 0 0 2 2 2 1 Pal1 cell morphology protein SelP_N PF04592.14 EEQ36568.1 - 7.7 5.8 8.8 13 5.1 8.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FYVE PF01363.21 EEQ36571.1 - 1.4e-14 54.0 5.2 2.7e-14 53.0 5.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EEQ36571.1 - 1.1 9.5 7.2 0.17 12.1 1.8 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger Pmp3 PF01679.17 EEQ36572.1 - 5.6e-16 58.5 10.7 5.7e-16 58.4 10.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ACOX PF01756.19 EEQ36573.1 - 3.7e-34 117.8 0.1 1.1e-33 116.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EEQ36573.1 - 5.6e-21 74.6 0.1 1e-20 73.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EEQ36573.1 - 5.2e-14 52.9 0.0 1.3e-13 51.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EEQ36573.1 - 4.5e-06 26.9 1.4 0.001 19.3 1.4 2.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 EEQ36574.1 - 6.4e-37 126.9 0.0 1.2e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EEQ36574.1 - 3.8e-22 78.3 0.1 7.4e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EEQ36574.1 - 2.2e-11 44.4 0.0 6e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EEQ36574.1 - 8.5e-06 26.0 0.0 0.0012 19.0 0.0 2.5 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Tom6 PF17112.5 EEQ36575.1 - 4.5e-24 83.7 2.7 5e-24 83.5 2.7 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal Bul1_N PF04425.12 EEQ36577.1 - 1.3e-89 301.0 2.7 4.1e-89 299.4 2.7 1.7 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 EEQ36577.1 - 2.1e-20 73.3 3.0 6.4e-10 38.9 0.0 3.5 3 1 1 4 4 4 2 Bul1 C terminus Transp_cyt_pur PF02133.15 EEQ36579.1 - 8.7e-11 41.2 41.0 6.1e-10 38.4 41.0 2.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rsa3 PF14615.6 EEQ36580.1 - 1.6e-18 65.9 0.2 1.6e-18 65.9 0.2 1.6 2 0 0 2 2 2 1 Ribosome-assembly protein 3 BNIP2 PF12496.8 EEQ36580.1 - 0.0089 16.5 9.4 0.012 16.0 9.4 1.3 1 0 0 1 1 1 1 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 CCSAP PF15748.5 EEQ36580.1 - 4.9 7.3 16.6 7.3 6.7 16.6 1.3 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated FAM76 PF16046.5 EEQ36580.1 - 8.8 5.6 12.7 11 5.3 12.7 1.1 1 0 0 1 1 1 0 FAM76 protein SHNi-TPR PF10516.9 EEQ36581.1 - 6.7e-18 63.9 1.1 1.9e-17 62.4 1.1 1.8 1 0 0 1 1 1 1 SHNi-TPR DUF3435 PF11917.8 EEQ36581.1 - 0.019 13.9 3.3 0.034 13.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Med13_C PF06333.12 EEQ36581.1 - 0.25 10.6 1.3 0.3 10.3 1.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Spectrin_like PF18373.1 EEQ36581.1 - 0.32 11.1 5.4 7.7 6.7 0.1 3.4 3 1 0 3 3 3 0 Spectrin like domain CNH PF00780.22 EEQ36582.1 - 1.4e-38 133.1 0.1 2.3e-38 132.4 0.1 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 EEQ36582.1 - 5.5e-09 36.2 0.0 1.9e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EEQ36582.1 - 0.0011 19.3 0.4 0.0024 18.1 0.4 1.6 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 EEQ36582.1 - 0.0014 19.1 0.0 0.0062 17.0 0.0 2.3 1 0 0 1 1 1 1 PH domain adh_short_C2 PF13561.6 EEQ36583.1 - 3.6e-43 147.8 0.1 4.4e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ36583.1 - 3.2e-42 144.2 0.3 3.9e-42 143.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ36583.1 - 1.8e-13 50.8 0.1 3.1e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ36583.1 - 0.003 17.0 0.0 0.0045 16.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EEQ36583.1 - 0.0058 15.8 0.1 0.0079 15.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EEQ36583.1 - 0.035 13.5 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase EF-hand_1 PF00036.32 EEQ36584.1 - 2.4e-25 86.2 15.3 4.6e-07 28.9 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EEQ36584.1 - 3.9e-23 81.7 7.5 1.9e-11 44.2 2.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EEQ36584.1 - 1.3e-21 74.6 10.8 1.9e-05 24.2 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EEQ36584.1 - 8e-16 56.7 16.8 0.00014 21.2 0.2 5.0 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 EEQ36584.1 - 1.9e-11 43.6 18.6 0.0009 19.0 1.7 4.6 2 1 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EEQ36584.1 - 2e-06 28.1 0.2 0.023 15.0 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EEQ36584.1 - 3e-05 23.9 10.7 0.42 10.6 0.3 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EEQ36584.1 - 0.00032 21.0 0.2 5 7.5 0.0 3.1 2 1 1 3 3 3 1 EF-hand domain Glycos_trans_3N PF02885.17 EEQ36584.1 - 0.059 13.2 0.0 38 4.2 0.0 3.1 2 1 1 3 3 3 0 Glycosyl transferase family, helical bundle domain Caleosin PF05042.13 EEQ36584.1 - 0.082 12.8 3.4 1.1 9.2 0.2 2.7 1 1 2 3 3 3 0 Caleosin related protein Sigma54_CBD PF04963.13 EEQ36584.1 - 0.097 12.5 0.0 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 Sigma-54 factor, core binding domain Fungal_TACC PF12709.7 EEQ36585.1 - 0.00053 20.4 1.2 0.0018 18.7 1.2 2.0 1 0 0 1 1 1 1 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3450 PF11932.8 EEQ36585.1 - 0.0019 17.6 1.9 0.0042 16.4 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Tropomyosin_1 PF12718.7 EEQ36585.1 - 0.0049 17.0 2.9 0.0049 17.0 2.9 3.1 3 0 0 3 3 3 1 Tropomyosin like IFT57 PF10498.9 EEQ36585.1 - 0.0093 15.0 2.1 0.017 14.1 2.1 1.4 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 ABC_tran_CTD PF16326.5 EEQ36585.1 - 0.023 14.9 0.4 0.023 14.9 0.4 3.3 3 1 0 3 3 3 0 ABC transporter C-terminal domain DUF5082 PF16888.5 EEQ36585.1 - 0.025 14.8 5.5 0.35 11.1 0.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) Transposon_TraM PF12508.8 EEQ36585.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Conjugative transposon, TraM Plasmid_RAQPRD PF09686.10 EEQ36585.1 - 0.061 13.5 0.2 2.1 8.6 0.0 3.4 4 1 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Seryl_tRNA_N PF02403.22 EEQ36585.1 - 0.11 12.7 10.4 0.021 15.0 5.6 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF5320 PF17253.2 EEQ36585.1 - 0.17 12.9 0.1 4.9 8.3 0.3 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5320) Spectrin PF00435.21 EEQ36585.1 - 0.17 12.3 5.9 0.21 12.1 0.7 2.8 2 1 0 2 2 2 0 Spectrin repeat Nas2_N PF18265.1 EEQ36585.1 - 0.24 11.4 2.0 5.4 7.0 0.0 3.4 2 1 1 3 3 3 0 Nas2 N_terminal domain XhlA PF10779.9 EEQ36585.1 - 0.26 11.5 2.3 0.39 10.9 0.6 2.4 2 0 0 2 2 1 0 Haemolysin XhlA KASH_CCD PF14662.6 EEQ36585.1 - 0.3 10.9 10.1 0.054 13.3 5.6 2.0 2 1 0 2 2 1 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EEQ36585.1 - 0.41 9.5 12.3 0.02 13.8 5.6 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EEQ36585.1 - 0.85 9.9 14.0 0.3 11.3 2.0 3.7 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding THOC7 PF05615.13 EEQ36585.1 - 1.1 9.6 11.6 0.07 13.4 4.2 2.4 2 1 0 2 2 2 0 Tho complex subunit 7 SHE3 PF17078.5 EEQ36585.1 - 1.1 8.9 12.5 0.087 12.5 2.6 2.8 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 EEQ36585.1 - 1.2 9.3 7.0 0.74 10.0 0.5 3.3 3 1 1 4 4 3 0 bZIP transcription factor DivIC PF04977.15 EEQ36585.1 - 1.7 8.5 5.8 0.34 10.7 0.4 2.5 3 0 0 3 3 2 0 Septum formation initiator BRE1 PF08647.11 EEQ36585.1 - 2.1 8.5 8.8 0.29 11.2 2.2 2.8 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 EEQ36585.1 - 3.4 7.0 9.3 0.15 11.4 2.2 2.3 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EEQ36585.1 - 4.7 7.2 9.0 0.53 10.3 1.4 2.9 3 0 0 3 3 3 0 Laminin Domain II APG6_N PF17675.1 EEQ36585.1 - 6 7.4 16.7 0.6 10.6 9.0 2.9 2 2 0 2 2 2 0 Apg6 coiled-coil region SEN1_N PF12726.7 EEQ36586.1 - 9.3e-153 510.2 22.9 9.3e-153 510.2 22.9 1.5 2 0 0 2 2 2 1 SEN1 N terminal AAA_11 PF13086.6 EEQ36586.1 - 3.9e-74 249.7 3.5 3.9e-74 249.7 3.5 2.9 4 0 0 4 4 4 1 AAA domain AAA_12 PF13087.6 EEQ36586.1 - 3.1e-67 226.1 0.0 8.4e-67 224.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ36586.1 - 7.4e-08 32.9 0.0 4.4e-07 30.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ36586.1 - 8.5e-08 32.1 0.0 0.00026 20.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EEQ36586.1 - 0.00029 20.7 6.5 0.08 12.7 0.0 4.1 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EEQ36586.1 - 0.048 13.4 0.1 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA PF00004.29 EEQ36586.1 - 0.054 13.9 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EEQ36586.1 - 0.055 13.5 0.2 0.49 10.4 0.2 2.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CDV3 PF15359.6 EEQ36586.1 - 0.094 13.2 2.7 0.32 11.5 2.7 1.9 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Fungal_trans_2 PF11951.8 EEQ36587.1 - 1.4e-42 145.9 0.1 2.1e-42 145.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain COPIIcoated_ERV PF07970.12 EEQ36588.1 - 1.4e-31 110.1 0.0 2.1e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EEQ36588.1 - 2.5e-22 79.0 0.0 4.4e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PSD2 PF07624.11 EEQ36588.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) Pex24p PF06398.11 EEQ36589.1 - 1.7e-89 300.4 1.5 2.1e-89 300.1 1.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Reticulon PF02453.17 EEQ36589.1 - 0.76 9.7 5.0 4 7.4 5.0 2.1 1 1 0 1 1 1 0 Reticulon Pkinase PF00069.25 EEQ36590.1 - 6.2e-47 160.2 0.0 3.2e-46 157.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36590.1 - 4.5e-26 91.7 0.0 7e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ36590.1 - 9.7 4.8 7.5 33 3.1 7.5 1.9 1 1 0 1 1 1 0 Fungal protein kinase SWC7 PF17330.2 EEQ36591.1 - 0.023 14.8 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 ABC_membrane_2 PF06472.15 EEQ36592.1 - 6.1e-65 219.3 0.0 8.1e-65 218.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EEQ36592.1 - 1.6e-19 70.8 0.0 3.5e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EEQ36592.1 - 0.016 15.7 1.8 0.14 12.6 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EEQ36592.1 - 0.018 14.8 0.1 0.044 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 EEQ36592.1 - 0.03 13.9 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DSX_dimer PF08828.10 EEQ36592.1 - 0.091 12.4 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Doublesex dimerisation domain IstB_IS21 PF01695.17 EEQ36592.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Pept_tRNA_hydro PF01195.19 EEQ36593.1 - 8.8e-42 143.0 0.0 1.1e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase ATG101 PF07855.12 EEQ36594.1 - 5.7e-18 65.4 0.0 6.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 PI-PLC-C1 PF16670.5 EEQ36594.1 - 0.063 12.4 0.0 0.091 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoinositide phospholipase C, Ca2+-dependent CoA_binding_2 PF13380.6 EEQ36595.1 - 1.3e-30 106.2 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain AbfS_sensor PF18225.1 EEQ36595.1 - 0.048 13.6 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain Zn_clus PF00172.18 EEQ36596.1 - 4.2e-05 23.6 7.3 7.8e-05 22.7 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Neur_chan_memb PF02932.16 EEQ36596.1 - 0.13 12.3 1.7 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region LRR_8 PF13855.6 EEQ36597.1 - 5.9e-08 32.4 7.7 1.5e-07 31.1 7.7 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EEQ36597.1 - 0.0038 17.6 12.1 0.11 12.9 3.1 3.8 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EEQ36597.1 - 0.042 13.4 0.3 2.8 7.4 0.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeat DUF2116 PF09889.9 EEQ36597.1 - 0.16 11.9 0.2 0.71 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) OB_NTP_bind PF07717.16 EEQ36598.1 - 3e-20 72.4 0.1 1e-19 70.6 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EEQ36598.1 - 2e-19 69.9 0.7 6.9e-19 68.1 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ36598.1 - 1.1e-14 54.7 0.0 3.3e-14 53.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EEQ36598.1 - 2.4e-07 31.1 0.0 7.4e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EEQ36598.1 - 1.1e-06 28.6 0.2 2.5e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EEQ36598.1 - 0.0036 17.6 0.1 0.01 16.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEQ36598.1 - 0.0051 15.9 0.0 0.021 13.9 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EEQ36598.1 - 0.024 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain YpjP PF14005.6 EEQ36598.1 - 0.084 12.9 0.6 4.5 7.3 0.1 2.6 2 0 0 2 2 2 0 YpjP-like protein PhoH PF02562.16 EEQ36598.1 - 0.089 12.2 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 EEQ36598.1 - 0.11 11.8 0.0 0.38 10.1 0.0 2.0 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.6 EEQ36598.1 - 0.16 12.0 3.1 5.8 7.0 0.2 3.5 2 1 0 2 2 2 0 AAA domain FUSC-like PF12805.7 EEQ36598.1 - 0.21 10.7 0.4 0.46 9.5 0.0 1.8 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS ABC_tran PF00005.27 EEQ36598.1 - 0.26 11.8 1.7 0.55 10.7 0.1 2.4 1 1 1 2 2 2 0 ABC transporter AAA_23 PF13476.6 EEQ36598.1 - 4.7 7.7 14.3 5.2 7.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 EEQ36599.1 - 7.6e-57 192.2 0.0 1.1e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EEQ36599.1 - 6.3e-37 127.0 0.0 9.5e-37 126.5 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EEQ36599.1 - 0.00022 21.8 0.0 0.00061 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ36599.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EEQ36599.1 - 0.0034 16.7 0.0 0.0063 15.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.14 EEQ36599.1 - 0.0074 15.6 0.0 0.0092 15.3 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain CPT PF07931.12 EEQ36599.1 - 0.0087 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein MobB PF03205.14 EEQ36599.1 - 0.023 14.6 0.0 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 EEQ36599.1 - 0.031 14.6 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EEQ36599.1 - 0.05 13.5 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase Aminotran_1_2 PF00155.21 EEQ36600.1 - 7.2e-43 147.1 0.0 1e-42 146.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EEQ36600.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Gaa1 PF04114.14 EEQ36601.1 - 2e-126 422.9 10.1 2.8e-126 422.5 10.1 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component 5TM-5TMR_LYT PF07694.12 EEQ36601.1 - 1.9 8.0 11.5 6.1 6.3 11.5 1.8 1 0 0 1 1 1 0 5TMR of 5TMR-LYT GEP5 PF17053.5 EEQ36602.1 - 2.2e-52 178.1 5.4 2.8e-52 177.8 5.4 1.1 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 Nrap_D4 PF17405.2 EEQ36602.1 - 0.01 15.2 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Nrap protein nucleotidyltransferase domain 4 ANAPC4 PF12896.7 EEQ36603.1 - 8.6e-57 191.9 2.4 8.6e-57 191.9 2.4 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EEQ36603.1 - 6.2e-20 71.3 0.1 1.6e-19 70.0 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain RhoGAP PF00620.27 EEQ36604.1 - 1.6e-15 57.2 0.0 5.1e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 RhoGAP domain Ribosomal_L1 PF00687.21 EEQ36605.1 - 6.7e-23 81.5 0.0 8.7e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family cNMP_binding PF00027.29 EEQ36606.1 - 3.8e-40 135.8 0.0 9.8e-21 73.6 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain F-box-like PF12937.7 EEQ36606.1 - 5.3e-09 35.8 0.1 1.4e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 EEQ36606.1 - 7.6e-09 34.9 10.1 3.3 8.0 0.0 7.9 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.7 EEQ36606.1 - 5.4e-07 29.8 8.3 0.037 14.5 0.1 5.6 5 2 1 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 EEQ36606.1 - 4e-06 26.6 0.8 2.2e-05 24.2 0.1 2.6 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 EEQ36606.1 - 0.00011 22.3 12.9 54 4.9 0.0 8.0 8 0 0 8 8 8 0 Leucine Rich Repeat Pre-PUA PF17832.1 EEQ36607.1 - 5.9e-19 68.5 2.6 1.3e-16 61.1 0.1 3.5 3 0 0 3 3 3 1 Pre-PUA-like domain SUI1 PF01253.22 EEQ36607.1 - 4.8e-16 59.1 0.0 1.9e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 Translation initiation factor SUI1 SWIB PF02201.18 EEQ36607.1 - 0.00075 19.3 0.1 0.002 17.9 0.1 1.8 1 0 0 1 1 1 1 SWIB/MDM2 domain Kin17_mid PF10357.9 EEQ36607.1 - 0.029 14.3 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Domain of Kin17 curved DNA-binding protein GBR_NSP5 PF17580.2 EEQ36607.1 - 0.56 10.0 3.5 0.83 9.5 1.1 2.1 2 0 0 2 2 2 0 Group B Rotavirus Non-structural protein 5 PIG-S PF10510.9 EEQ36608.1 - 4.7e-113 378.7 4.3 5.7e-113 378.5 4.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein RasGEF PF00617.19 EEQ36610.1 - 3.5e-44 151.1 4.7 8.9e-44 149.8 2.5 2.6 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EEQ36610.1 - 7.3e-12 45.4 0.4 2.6e-11 43.7 0.4 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif IFT46_B_C PF12317.8 EEQ36610.1 - 0.071 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Aconitase PF00330.20 EEQ36611.1 - 3.9e-149 497.6 0.0 5.1e-149 497.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEQ36611.1 - 1.8e-42 144.8 0.0 3.4e-42 143.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ATP-synt_ab PF00006.25 EEQ36612.1 - 1.5e-66 224.1 0.0 3.6e-66 222.8 0.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EEQ36612.1 - 9.8e-13 48.4 0.6 1.9e-12 47.5 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EEQ36612.1 - 0.066 13.4 0.4 0.18 12.0 0.3 1.8 2 0 0 2 2 2 0 HAS barrel domain Atg14 PF10186.9 EEQ36613.1 - 0.0008 18.6 5.4 0.0008 18.6 5.4 2.2 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 YqgF PF14639.6 EEQ36613.1 - 0.047 13.5 5.3 0.33 10.7 0.1 2.6 2 0 0 2 2 2 0 Holliday-junction resolvase-like of SPT6 Siah-Interact_N PF09032.11 EEQ36613.1 - 0.42 10.9 3.9 0.4 11.0 1.4 2.5 2 0 0 2 2 2 0 Siah interacting protein, N terminal KxDL PF10241.9 EEQ36613.1 - 0.64 10.3 5.6 0.76 10.1 1.7 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein CLZ PF16526.5 EEQ36613.1 - 0.69 10.3 3.7 0.68 10.3 0.4 2.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MMR_HSR1 PF01926.23 EEQ36614.1 - 0.038 14.1 0.1 0.13 12.3 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Ras PF00071.22 EEQ36614.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Ras family Glyco_hydro_130 PF04041.13 EEQ36615.1 - 1e-44 152.8 0.0 1.4e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 EEQ36615.1 - 4.8e-08 32.9 1.5 5.9e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 EEQ36615.1 - 3.7e-05 23.2 0.3 1.5 8.1 0.0 4.0 3 1 0 4 4 4 2 Glycosyl hydrolases family 43 2CSK_N PF08521.10 EEQ36615.1 - 0.084 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal PP2C PF00481.21 EEQ36616.1 - 2.2e-51 175.0 0.0 2.8e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EEQ36616.1 - 0.0024 17.5 0.0 0.0058 16.3 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C Glyco_transf_20 PF00982.21 EEQ36618.1 - 5.2e-202 671.7 0.0 5.9e-202 671.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 EEQ36618.1 - 9.8e-05 22.0 1.7 0.047 13.2 0.2 3.0 2 1 0 2 2 2 2 Glycosyl transferases group 1 MBA1 PF07961.11 EEQ36618.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 MBA1-like protein Glyco_transf_5 PF08323.11 EEQ36618.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain YIF1 PF03878.15 EEQ36619.1 - 1.5e-86 289.8 5.6 1.9e-86 289.5 5.6 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EEQ36619.1 - 0.57 9.9 14.5 0.31 10.7 10.5 2.1 1 1 1 2 2 2 0 Yip1 domain DNA_pol_B_exo1 PF03104.19 EEQ36620.1 - 1.9e-79 267.3 1.7 4.2e-79 266.1 1.7 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EEQ36620.1 - 1.1e-18 67.3 0.4 1.8e-16 59.9 0.3 2.4 2 0 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EEQ36620.1 - 1.8e-06 27.8 1.1 7.1e-06 25.8 1.1 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EEQ36620.1 - 9.4e-05 22.5 2.3 0.00017 21.6 0.1 2.7 4 0 0 4 4 4 1 RNase_H superfamily DUF1098 PF06497.11 EEQ36620.1 - 0.012 16.1 0.2 1.3 9.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) PLAT PF01477.23 EEQ36620.1 - 0.019 15.5 0.3 0.1 13.2 0.0 2.5 2 0 0 2 2 2 0 PLAT/LH2 domain NAPRTase_C PF17956.1 EEQ36620.1 - 0.051 14.0 0.0 0.26 11.7 0.0 2.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF1744 PF08490.12 EEQ36621.1 - 1.9e-137 458.1 2.4 2.9e-137 457.5 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) Cytochrome_C7 PF14522.6 EEQ36621.1 - 1.3 9.1 9.0 3 7.9 9.0 1.5 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 EEQ36621.1 - 2.5 8.6 10.5 4.9 7.7 10.5 1.4 1 0 0 1 1 1 0 Cytochrome c3 ORC5_C PF14630.6 EEQ36622.1 - 7.2e-71 239.0 2.2 9.1e-71 238.7 2.2 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EEQ36622.1 - 6.4e-06 26.7 0.0 1.7e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EEQ36622.1 - 0.032 14.3 0.1 0.13 12.3 0.1 2.3 1 1 0 1 1 1 0 AAA domain BTB PF00651.31 EEQ36622.1 - 0.039 14.2 0.7 0.2 11.9 0.2 2.4 3 0 0 3 3 3 0 BTB/POZ domain SAM_3 PF18016.1 EEQ36622.1 - 0.058 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FAM124 PF15067.6 EEQ36622.1 - 0.064 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 FAM124 family AAA_5 PF07728.14 EEQ36622.1 - 0.11 12.5 0.0 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GYF PF02213.16 EEQ36623.1 - 4.9e-14 51.7 1.9 1.2e-13 50.5 1.9 1.7 1 0 0 1 1 1 1 GYF domain Yae1_N PF09811.9 EEQ36624.1 - 1.6e-07 30.9 7.4 2.6e-07 30.2 7.4 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal HeLo PF14479.6 EEQ36624.1 - 0.016 15.0 0.4 0.025 14.4 0.4 1.2 1 0 0 1 1 1 0 Prion-inhibition and propagation WD40 PF00400.32 EEQ36625.1 - 0.00026 21.7 9.7 0.0014 19.4 0.4 4.5 4 1 0 4 4 4 1 WD domain, G-beta repeat adh_short PF00106.25 EEQ36626.1 - 1.7e-20 73.3 0.0 3.1e-17 62.7 0.0 3.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ36626.1 - 1e-11 44.8 0.0 6.1e-10 39.1 0.0 2.6 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ36626.1 - 0.0025 17.7 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EEQ36626.1 - 0.03 14.2 0.0 0.05 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.21 EEQ36626.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EEQ36626.1 - 0.1 12.0 0.1 0.88 8.9 0.1 2.1 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) ISN1 PF06437.11 EEQ36627.1 - 2.5e-176 586.6 0.0 2.8e-176 586.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Glycos_transf_1 PF00534.20 EEQ36627.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ribosomal_S4e PF00900.20 EEQ36628.1 - 1.4e-35 121.1 0.5 2.3e-35 120.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal family S4e S4 PF01479.25 EEQ36628.1 - 5.9e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain RS4NT PF08071.12 EEQ36628.1 - 6e-08 32.7 0.1 1.3e-07 31.6 0.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.29 EEQ36628.1 - 2.1e-05 24.3 3.9 2.1e-05 24.3 3.9 3.0 3 0 0 3 3 3 1 KOW motif Sipho_tail PF05709.11 EEQ36628.1 - 0.032 13.6 0.1 0.11 11.9 0.1 1.7 1 1 0 1 1 1 0 Phage tail protein S4_2 PF13275.6 EEQ36628.1 - 0.082 12.7 0.0 0.44 10.4 0.0 2.1 2 0 0 2 2 2 0 S4 domain CIA30 PF08547.12 EEQ36629.1 - 6.1e-46 156.4 0.0 8.1e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 EEQ36629.1 - 0.0056 16.7 0.3 0.07 13.1 0.0 2.1 2 0 0 2 2 2 1 Surface glycan-binding protein B xyloglucan binding domain CBM_11 PF03425.13 EEQ36629.1 - 0.01 15.7 0.2 0.018 14.9 0.2 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) PNP_UDP_1 PF01048.20 EEQ36630.1 - 3.5e-37 127.9 0.0 4.1e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DAGAT PF03982.13 EEQ36632.1 - 2.6e-53 180.9 6.0 9.2e-29 100.3 0.1 5.1 3 2 1 4 4 4 4 Diacylglycerol acyltransferase ORC_WH_C PF18137.1 EEQ36633.1 - 2.2e-26 92.6 0.2 2.2e-26 92.6 0.2 2.5 2 0 0 2 2 2 1 Origin recognition complex winged helix C-terminal ORC3_N PF07034.11 EEQ36633.1 - 2.2e-25 89.5 2.5 2.1e-20 73.1 0.3 3.1 3 1 0 3 3 3 2 Origin recognition complex (ORC) subunit 3 N-terminus NRDE-2 PF08424.10 EEQ36633.1 - 0.01 15.0 0.4 0.024 13.8 0.4 1.6 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Sigma70_ner PF04546.13 EEQ36633.1 - 0.099 12.5 9.1 0.8 9.6 6.7 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region FliT PF05400.13 EEQ36633.1 - 0.17 12.8 1.2 0.52 11.2 0.1 2.4 2 0 0 2 2 2 0 Flagellar protein FliT HLH PF00010.26 EEQ36634.1 - 1.7e-18 66.3 0.2 5.5e-18 64.7 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain V_ATPase_I PF01496.19 EEQ36635.1 - 5.4e-287 954.1 14.9 6.3e-222 738.9 12.0 2.0 2 0 0 2 2 2 2 V-type ATPase 116kDa subunit family Sel1 PF08238.12 EEQ36636.1 - 9.4e-23 80.2 23.0 0.00023 21.8 0.0 8.9 10 0 0 10 10 10 6 Sel1 repeat Dna2 PF08696.11 EEQ36637.1 - 2.8e-54 184.0 0.1 5.9e-54 183.0 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 EEQ36637.1 - 8.3e-51 172.5 1.8 1.2e-50 171.9 0.2 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EEQ36637.1 - 8.2e-31 107.7 1.6 3.1e-14 53.4 0.0 2.8 2 1 1 3 3 2 2 AAA domain AAA_30 PF13604.6 EEQ36637.1 - 2.1e-12 47.1 0.0 4.5e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ36637.1 - 1.5e-11 44.8 0.0 3.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EEQ36637.1 - 1.8e-06 27.9 0.7 0.09 12.5 0.0 4.0 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 EEQ36637.1 - 6.4e-06 25.9 1.0 9.8e-05 22.0 0.0 2.9 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 EEQ36637.1 - 0.00017 21.2 0.0 0.00058 19.5 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Cas_Cas4 PF01930.17 EEQ36637.1 - 0.00039 20.6 0.1 0.0037 17.4 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 KTI12 PF08433.10 EEQ36637.1 - 0.0023 17.4 0.1 0.79 9.1 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EEQ36637.1 - 0.0037 17.8 0.0 0.018 15.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 EEQ36637.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 EEQ36637.1 - 0.0076 15.9 0.1 0.02 14.5 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 EEQ36637.1 - 0.012 15.6 1.1 0.073 13.1 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 EEQ36637.1 - 0.013 15.3 0.0 0.05 13.5 0.0 2.0 1 1 0 1 1 1 0 Helicase AAA_7 PF12775.7 EEQ36637.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EEQ36637.1 - 0.015 14.7 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_5 PF07728.14 EEQ36637.1 - 0.025 14.6 0.0 0.059 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ36637.1 - 0.025 14.8 0.0 0.066 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EEQ36637.1 - 0.026 14.6 1.6 0.16 12.1 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain CbiA PF01656.23 EEQ36637.1 - 0.03 14.4 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Sigma54_activat PF00158.26 EEQ36637.1 - 0.056 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 EEQ36637.1 - 0.064 13.4 0.0 0.22 11.7 0.0 2.0 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 EEQ36637.1 - 0.11 11.8 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EEQ36637.1 - 0.14 12.0 0.3 0.5 10.3 0.1 2.1 2 0 0 2 2 2 0 NTPase Nop PF01798.18 EEQ36638.1 - 1e-83 280.3 0.2 1e-83 280.3 0.2 2.1 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EEQ36638.1 - 1.4e-19 70.2 2.9 1.4e-19 70.2 2.9 2.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain PAD PF03068.15 EEQ36638.1 - 0.06 12.3 0.5 0.095 11.7 0.5 1.3 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) GAGA_bind PF06217.12 EEQ36638.1 - 0.75 10.0 22.3 1.6 9.0 22.3 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 EEQ36638.1 - 3.7 7.3 31.8 1.1 9.0 28.6 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EOS1 PF12326.8 EEQ36638.1 - 8.4 6.3 8.1 16 5.4 8.1 1.6 1 0 0 1 1 1 0 N-glycosylation protein AA_permease PF00324.21 EEQ36639.1 - 9.1e-148 492.8 37.9 1.1e-147 492.5 37.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ36639.1 - 2e-43 148.8 40.2 2.4e-43 148.6 40.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ36640.1 - 4.3e-98 329.0 31.1 5.6e-98 328.6 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ36640.1 - 8.1e-26 90.8 33.6 1e-25 90.4 33.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EEQ36640.1 - 0.005 15.7 0.7 0.0077 15.1 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) Aldolase_II PF00596.21 EEQ36641.1 - 1.7e-42 145.5 0.0 2.1e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Prenyltrans PF00432.21 EEQ36642.1 - 1.9e-59 197.0 4.5 1.1e-12 47.5 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EEQ36642.1 - 1.5e-06 27.6 0.0 0.024 13.7 0.0 3.6 2 2 2 4 4 4 3 Squalene-hopene cyclase N-terminal domain DNA_pol_E_B PF04042.16 EEQ36643.1 - 9.5e-40 136.2 0.2 1.4e-39 135.6 0.2 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EEQ36643.1 - 0.015 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain CALCOCO1 PF07888.11 EEQ36644.1 - 2.2 7.1 50.8 1 8.1 20.2 2.4 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like FlgM PF04316.13 EEQ36644.1 - 9.8 6.6 8.9 13 6.3 0.3 3.3 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM Glyco_hydro_3_C PF01915.22 EEQ36645.1 - 8.2e-48 163.1 0.0 1.1e-47 162.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EEQ36645.1 - 6.5e-37 127.6 0.0 1.1e-36 126.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EEQ36645.1 - 1.5e-19 69.9 0.0 2.6e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain LRR_8 PF13855.6 EEQ36646.1 - 4.6e-13 48.7 20.9 7.3e-09 35.3 1.2 4.7 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 EEQ36646.1 - 5.4e-10 39.4 36.9 2.1e-05 24.8 2.2 5.2 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EEQ36646.1 - 0.00027 20.5 6.7 0.001 18.6 5.7 2.3 1 1 1 2 2 2 1 Leucine-rich repeat LRR_5 PF13306.6 EEQ36646.1 - 0.066 13.2 6.1 0.14 12.1 2.3 3.2 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_6 PF13516.6 EEQ36646.1 - 8.7 6.7 16.2 1.7 8.9 1.2 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Cu_amine_oxid PF01179.20 EEQ36648.1 - 1.7e-154 514.7 0.1 2.1e-154 514.4 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF4452 PF14618.6 EEQ36649.1 - 0.0001 22.3 21.4 0.00023 21.1 2.4 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF4452) Peptidase_M16 PF00675.20 EEQ36650.1 - 5.3e-20 71.9 0.3 1.4e-19 70.5 0.1 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEQ36650.1 - 1.2e-08 35.2 0.3 0.014 15.4 0.0 5.0 6 0 0 6 6 6 2 Peptidase M16 inactive domain Peptidase_M16_M PF16187.5 EEQ36650.1 - 4.5e-07 29.5 0.1 1e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 zf-C3H2C3 PF17122.5 EEQ36650.1 - 0.093 12.8 0.6 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Zinc-finger 2OG-FeII_Oxy PF03171.20 EEQ36651.1 - 0.00052 20.5 0.0 0.0023 18.4 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EEQ36651.1 - 0.0035 18.1 0.0 0.0072 17.1 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_C74 PF12387.8 EEQ36651.1 - 0.055 12.9 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase WD40 PF00400.32 EEQ36652.1 - 1.5e-36 123.7 21.7 8.5e-10 39.1 0.3 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36652.1 - 1.4e-14 54.1 0.3 0.014 15.7 0.0 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 EEQ36652.1 - 3.4e-12 45.7 3.9 5.8e-12 45.0 3.9 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 EEQ36652.1 - 1.6e-05 24.1 0.2 3.6 6.5 0.0 5.1 1 1 5 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DHFR_2 PF06442.11 EEQ36652.1 - 0.034 14.0 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 R67 dihydrofolate reductase Nbas_N PF15492.6 EEQ36652.1 - 0.035 13.4 0.5 14 4.9 0.0 3.7 2 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal HDA2-3 PF11496.8 EEQ36653.1 - 5.8e-99 330.9 2.4 5.8e-99 330.9 2.4 1.9 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF4200 PF13863.6 EEQ36653.1 - 0.0012 19.2 14.2 0.0012 19.2 14.2 3.7 2 1 2 4 4 4 1 Domain of unknown function (DUF4200) PilJ PF13675.6 EEQ36653.1 - 0.1 12.6 4.2 0.061 13.4 0.9 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HALZ PF02183.18 EEQ36653.1 - 0.14 12.4 4.6 0.53 10.6 0.3 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper GAT PF03127.14 EEQ36653.1 - 2.2 8.6 8.4 0.51 10.7 0.8 3.5 2 1 0 2 2 2 0 GAT domain DUF1515 PF07439.11 EEQ36653.1 - 3.4 7.7 9.7 1.9 8.5 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1515) TMPIT PF07851.13 EEQ36653.1 - 4.8 6.3 24.0 1.6 7.9 10.8 2.4 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin-6_N PF09177.11 EEQ36653.1 - 7.1 7.2 20.5 1.1 9.8 5.5 4.1 2 1 0 3 3 3 0 Syntaxin 6, N-terminal Sec23_trunk PF04811.15 EEQ36656.1 - 1.1e-71 241.2 0.0 1.8e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EEQ36656.1 - 5.6e-33 113.6 0.1 1.2e-32 112.5 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EEQ36656.1 - 1.1e-24 86.2 0.2 3.2e-24 84.7 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EEQ36656.1 - 8.7e-12 44.8 0.0 1.9e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 EEQ36656.1 - 4.9e-11 42.5 9.1 1.1e-10 41.4 9.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger CK_II_beta PF01214.18 EEQ36657.1 - 1.4e-64 217.3 0.0 1.9e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CHD5 PF04420.14 EEQ36658.1 - 4.1e-51 173.0 2.2 5.2e-51 172.7 2.2 1.1 1 0 0 1 1 1 1 CHD5-like protein WD40 PF00400.32 EEQ36659.1 - 4.3e-28 97.0 10.0 1.4e-08 35.2 0.0 7.3 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36659.1 - 1.4e-13 51.0 0.0 0.065 13.5 0.0 5.9 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EEQ36659.1 - 2.7e-10 40.3 0.2 2.7e-10 40.3 0.2 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split HIRA_B PF09453.10 EEQ36659.1 - 2.8e-10 39.8 0.8 8.6e-10 38.2 0.8 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EEQ36659.1 - 9.5e-07 28.6 0.1 6.1 6.9 0.0 4.5 4 0 0 4 4 4 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EEQ36659.1 - 0.023 13.7 0.1 0.67 8.9 0.0 2.9 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PLN_propep PF16485.5 EEQ36659.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Protealysin propeptide Aminotran_1_2 PF00155.21 EEQ36660.1 - 2.9e-24 85.9 0.0 3.4e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EEQ36660.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase HPS3_Mid PF14762.6 EEQ36660.1 - 0.023 13.5 0.8 0.11 11.2 0.1 1.9 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3, middle region DegT_DnrJ_EryC1 PF01041.17 EEQ36660.1 - 0.064 12.6 0.1 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family WD40 PF00400.32 EEQ36661.1 - 1.1e-25 89.4 16.0 1.1e-05 26.1 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36661.1 - 2.4e-18 66.2 7.9 9.4e-08 32.3 0.6 4.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ36661.1 - 1.5e-07 31.5 1.9 0.0012 18.7 0.3 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EEQ36661.1 - 0.0043 16.1 0.0 0.063 12.2 0.0 2.2 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein 2Fe-2S_thioredx PF01257.19 EEQ36662.1 - 5.5e-60 201.4 0.4 7.1e-60 201.1 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Cys_Met_Meta_PP PF01053.20 EEQ36664.1 - 8.6e-136 452.4 0.0 9.8e-136 452.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EEQ36664.1 - 0.00018 21.0 0.0 0.02 14.2 0.0 2.8 2 1 1 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EEQ36664.1 - 0.00027 20.2 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EEQ36664.1 - 0.0029 16.6 0.3 0.0061 15.6 0.1 1.6 2 0 0 2 2 2 1 Aminotransferase class-V DUF2732 PF10809.8 EEQ36664.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) Rep_fac-A_C PF08646.10 EEQ36665.1 - 3.7e-56 188.9 8.3 3e-54 182.8 1.1 3.4 3 1 0 4 4 4 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EEQ36665.1 - 1.4e-34 117.9 0.8 1.4e-32 111.5 0.1 3.2 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EEQ36665.1 - 6.5e-18 64.5 0.2 5.4e-10 39.1 0.0 4.6 4 1 1 5 5 5 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 EEQ36665.1 - 8.9e-11 41.7 0.1 2.8e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain CDC24_OB3 PF17244.2 EEQ36665.1 - 1.6e-05 24.7 1.1 0.11 12.2 0.0 3.4 2 1 1 3 3 3 2 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 EEQ36665.1 - 0.061 13.6 0.4 0.21 11.9 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF223 BRCA-2_OB1 PF09103.10 EEQ36665.1 - 0.087 12.8 0.1 2.4 8.1 0.0 2.6 3 0 0 3 3 3 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 TPP1 PF10341.9 EEQ36665.1 - 0.09 12.8 0.1 2 8.4 0.1 2.6 2 0 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD Creatinase_N_2 PF16189.5 EEQ36667.1 - 3.1e-48 163.9 2.4 3.1e-48 163.9 2.4 2.0 2 1 1 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EEQ36667.1 - 8.8e-40 136.6 0.0 1.4e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EEQ36667.1 - 3.5e-24 84.6 0.2 9e-24 83.3 0.2 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EEQ36667.1 - 1.6e-20 74.1 0.0 8.3e-12 45.9 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Fe-S_biosyn PF01521.20 EEQ36668.1 - 3.9e-19 68.9 0.0 5.7e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF4551 PF15087.6 EEQ36668.1 - 2.4 6.9 5.5 2.7 6.7 5.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Sod_Cu PF00080.20 EEQ36669.1 - 4.9e-14 52.7 0.0 4.9e-14 52.7 0.0 2.3 3 1 0 3 3 3 1 Copper/zinc superoxide dismutase (SODC) DUF1385 PF07136.11 EEQ36672.1 - 0.024 13.9 0.0 0.34 10.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1385) Mob1_phocein PF03637.17 EEQ36673.1 - 2.1e-72 242.7 0.1 2.6e-72 242.3 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family Med5 PF08689.10 EEQ36673.1 - 0.034 12.0 0.5 0.054 11.3 0.0 1.4 2 0 0 2 2 2 0 Mediator complex subunit Med5 Exo_endo_phos PF03372.23 EEQ36674.1 - 1.4e-24 86.9 0.0 2.1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ANAPC_CDC26 PF10471.9 EEQ36674.1 - 0.094 13.6 1.1 1.7 9.5 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 FYDLN_acid PF09538.10 EEQ36674.1 - 0.12 13.1 3.0 0.23 12.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) SMC_hinge PF06470.13 EEQ36675.1 - 0.085 13.2 0.0 0.35 11.2 0.0 2.2 1 1 0 1 1 1 0 SMC proteins Flexible Hinge Domain TPR_8 PF13181.6 EEQ36675.1 - 0.33 11.3 4.7 16 6.0 1.1 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat SMC_N PF02463.19 EEQ36675.1 - 0.41 10.0 36.3 0.38 10.1 32.5 3.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain SCO1-SenC PF02630.14 EEQ36675.1 - 0.75 9.7 3.1 2 8.3 0.4 3.0 3 0 0 3 3 3 0 SCO1/SenC Vip3A_N PF12495.8 EEQ36675.1 - 1.7 8.5 15.1 0.26 11.2 7.4 3.1 3 1 0 3 3 3 0 Vegetative insecticide protein 3A N terminal DUF1400 PF07176.11 EEQ36676.1 - 0.033 14.5 0.3 1.3 9.3 0.0 3.2 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF1400) 60KD_IMP PF02096.20 EEQ36677.1 - 8.1e-28 97.4 3.3 8.1e-28 97.4 3.3 2.0 2 0 0 2 2 2 1 60Kd inner membrane protein RhoGAP PF00620.27 EEQ36678.1 - 2.7e-35 121.5 0.0 7.6e-35 120.0 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.19 EEQ36678.1 - 9.3e-18 65.0 0.8 1.1e-14 55.1 0.0 3.1 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.20 EEQ36678.1 - 1.3e-14 54.3 1.5 5.7e-14 52.2 1.5 2.2 1 0 0 1 1 1 1 RasGEF N-terminal motif PH PF00169.29 EEQ36678.1 - 0.0008 19.9 0.7 0.0037 17.8 0.1 2.5 2 0 0 2 2 2 1 PH domain Cpn60_TCP1 PF00118.24 EEQ36678.1 - 0.15 10.6 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 TCP-1/cpn60 chaperonin family MKT1_C PF12246.8 EEQ36679.1 - 2.7e-53 180.7 0.6 2.7e-53 180.7 0.6 1.7 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EEQ36679.1 - 4.6e-26 91.0 0.2 1.3e-25 89.5 0.2 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EEQ36679.1 - 2.3e-14 53.7 0.0 2e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EEQ36679.1 - 2.6e-07 30.9 0.0 6.6e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 XPG I-region AIM24 PF01987.17 EEQ36680.1 - 7.4e-13 48.7 0.1 1e-12 48.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Ins_P5_2-kin PF06090.12 EEQ36681.1 - 2.4e-26 92.9 0.0 2.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase FAD_binding_1 PF00667.20 EEQ36682.1 - 3.1e-73 246.0 0.0 4.4e-73 245.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EEQ36682.1 - 1.7e-34 119.1 0.9 3.4e-34 118.1 0.9 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EEQ36682.1 - 1.2e-19 70.9 0.0 4e-19 69.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 EEQ36682.1 - 0.062 13.5 0.2 0.16 12.1 0.2 1.7 1 0 0 1 1 1 0 NrdI Flavodoxin like MAGE PF01454.19 EEQ36683.1 - 7.1e-28 97.8 1.0 8.2e-27 94.3 1.0 2.1 1 1 0 1 1 1 1 MAGE family zf-RING_UBOX PF13445.6 EEQ36684.1 - 1.7e-08 34.3 9.1 1.7e-08 34.3 9.1 2.5 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EEQ36684.1 - 1.1e-06 28.9 6.3 1.1e-06 28.9 6.3 3.4 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ36684.1 - 1.8e-06 27.7 6.5 1.8e-06 27.7 6.5 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ36684.1 - 2.4e-06 27.3 6.6 2.4e-06 27.3 6.6 3.0 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ36684.1 - 4.8e-06 26.6 8.0 4.8e-06 26.6 8.0 2.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EEQ36684.1 - 4.3e-05 23.3 3.4 4.3e-05 23.3 3.4 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ36684.1 - 0.0001 22.2 5.6 0.0001 22.2 5.6 3.3 2 1 0 2 2 1 1 zinc-RING finger domain zf-Nse PF11789.8 EEQ36684.1 - 0.00014 21.6 2.3 0.00014 21.6 2.3 2.6 2 1 0 2 2 1 1 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.21 EEQ36684.1 - 0.00023 21.3 10.6 0.09 12.9 4.6 3.5 2 2 1 3 3 3 2 FYVE zinc finger Spore_Cse60 PF10957.8 EEQ36684.1 - 0.04 13.9 0.4 6.2 6.9 0.1 2.7 1 1 1 2 2 2 0 Sporulation protein Cse60 bZIP_1 PF00170.21 EEQ36684.1 - 0.082 13.0 0.1 0.082 13.0 0.1 2.6 3 0 0 3 3 3 0 bZIP transcription factor zf-RING_6 PF14835.6 EEQ36684.1 - 0.22 11.4 5.2 0.83 9.6 5.2 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein ZapB PF06005.12 EEQ36684.1 - 0.43 11.0 4.3 3.5 8.1 4.1 2.4 1 1 0 1 1 1 0 Cell division protein ZapB DUF2408 PF10303.9 EEQ36684.1 - 1.3 9.6 5.7 0.58 10.7 2.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PP2C_C PF07830.13 EEQ36684.1 - 4.3 7.9 5.7 38 4.8 0.2 3.3 3 1 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Oxysterol_BP PF01237.18 EEQ36685.1 - 4.1e-99 331.9 0.1 1.2e-98 330.4 0.1 1.8 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EEQ36685.1 - 1.5e-36 124.5 0.7 3.9e-36 123.2 0.7 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EEQ36685.1 - 1.5e-05 25.4 0.3 9.4e-05 22.9 0.3 2.4 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EEQ36685.1 - 2.6e-05 24.3 0.5 5.9e-05 23.1 0.5 1.6 1 0 0 1 1 1 1 PH domain DUF3830 PF12903.7 EEQ36685.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) MFS_1 PF07690.16 EEQ36686.1 - 1.3e-44 152.6 53.4 1.8e-36 125.8 27.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ36686.1 - 1.8e-06 27.1 15.2 1.8e-06 27.1 15.2 3.4 3 1 1 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.13 EEQ36686.1 - 5.6e-06 25.1 10.8 1.1e-05 24.1 10.8 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EEQ36686.1 - 1.3 7.2 20.6 0.017 13.4 3.2 2.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EamA PF00892.20 EEQ36687.1 - 1.6e-12 47.8 31.1 2.8e-10 40.5 4.3 3.6 3 1 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EEQ36687.1 - 1.2e-08 34.6 1.1 1.2e-08 34.6 1.1 2.6 3 0 0 3 3 3 2 Purine nucleobase transmembrane transport SLC35F PF06027.12 EEQ36687.1 - 1.5e-06 28.0 3.7 1.5e-06 28.0 3.7 2.3 1 1 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 EEQ36687.1 - 8.7e-05 21.9 9.1 8.7e-05 21.9 9.1 1.7 2 0 0 2 2 2 1 UAA transporter family DIOX_N PF14226.6 EEQ36688.1 - 7.5e-20 71.9 0.0 1.4e-19 71.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EEQ36688.1 - 4.5e-14 52.8 0.0 8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNase_H2_suC PF08615.11 EEQ36689.1 - 5.2e-15 55.8 0.3 1.1e-13 51.6 0.3 2.0 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) RSN1_7TM PF02714.15 EEQ36690.1 - 5e-70 235.9 24.5 5e-70 235.9 24.5 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEQ36690.1 - 2.7e-27 95.5 7.2 2.7e-27 95.5 7.2 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EEQ36690.1 - 2.5e-11 44.1 0.2 3.6e-11 43.6 0.2 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EEQ36690.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Met_10 PF02475.16 EEQ36691.1 - 1.5e-71 240.3 0.0 2.4e-71 239.6 0.0 1.4 1 1 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EEQ36691.1 - 0.00049 19.4 0.0 0.00085 18.6 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.15 EEQ36691.1 - 0.0062 16.3 0.0 0.0098 15.6 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase ECR1_N PF14382.6 EEQ36692.1 - 5.8e-17 61.2 0.6 3.7e-16 58.6 0.2 2.3 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EEQ36692.1 - 5.4e-08 33.1 0.1 1.1e-07 32.0 0.1 1.6 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EEQ36692.1 - 0.095 13.3 0.3 20 5.8 0.0 3.0 2 2 1 3 3 3 0 Exosome component EXOSC1/CSL4 EMP24_GP25L PF01105.24 EEQ36693.1 - 1.2e-21 77.5 3.8 2e-21 76.8 3.8 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Muted PF14942.6 EEQ36693.1 - 0.072 13.4 4.0 0.15 12.4 4.0 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Tox-HDC PF15656.6 EEQ36693.1 - 0.2 11.8 5.7 3.1 8.0 0.8 2.3 1 1 1 2 2 2 0 Toxin with a H, D/N and C signature Oxysterol_BP PF01237.18 EEQ36694.1 - 1e-130 435.9 0.1 1e-130 435.9 0.1 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_5 PF13857.6 EEQ36694.1 - 1.3e-14 54.0 0.0 1.8e-07 31.3 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ36694.1 - 2.1e-14 53.9 0.0 1e-08 35.7 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ36694.1 - 3.2e-14 53.1 0.0 8e-09 35.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ36694.1 - 1e-13 50.1 0.1 0.00025 21.2 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EEQ36694.1 - 3.7e-09 36.6 0.1 8.1e-05 22.9 0.3 4.1 4 0 0 4 4 4 1 Ankyrin repeat PH_8 PF15409.6 EEQ36694.1 - 1.3e-07 31.8 0.2 4.9e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EEQ36694.1 - 2.4e-07 31.2 0.1 2.4e-07 31.2 0.1 2.2 2 0 0 2 2 2 1 PH domain Swi5 PF07061.11 EEQ36694.1 - 0.21 11.7 4.0 0.31 11.1 0.3 2.8 1 1 1 2 2 2 0 Swi5 WD40 PF00400.32 EEQ36695.1 - 0.47 11.4 0.0 0.47 11.4 0.0 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat SDA1 PF05285.12 EEQ36695.1 - 3.3 7.0 31.6 0.28 10.6 25.9 1.8 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 EEQ36695.1 - 7.3 4.7 18.8 13 3.9 18.8 1.3 1 0 0 1 1 1 0 CDC45-like protein Myotub-related PF06602.14 EEQ36696.1 - 1.3e-142 475.0 3.0 1.6e-142 474.7 3.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EEQ36696.1 - 0.0051 16.8 0.0 0.017 15.1 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EEQ36696.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase MelC1 PF06236.11 EEQ36696.1 - 0.024 14.7 0.5 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Tyrosinase co-factor MelC1 DUF5426 PF17473.2 EEQ36696.1 - 0.056 13.7 0.1 0.91 9.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5426) SAT PF16073.5 EEQ36696.1 - 0.064 13.0 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DSPc PF00782.20 EEQ36696.1 - 0.066 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain AFG1_ATPase PF03969.16 EEQ36697.1 - 2.7e-58 197.6 0.5 6.9e-55 186.4 0.2 3.0 1 1 1 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.6 EEQ36697.1 - 0.026 14.8 0.0 0.17 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 EEQ36697.1 - 0.067 13.1 0.1 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain SF3A2 PF16835.5 EEQ36697.1 - 0.096 13.1 0.1 0.29 11.5 0.1 1.8 1 1 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) DCX PF03607.17 EEQ36697.1 - 0.12 12.5 0.0 2 8.6 0.0 2.8 2 1 0 2 2 2 0 Doublecortin AAA_29 PF13555.6 EEQ36697.1 - 0.13 12.0 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ36697.1 - 0.17 12.2 0.0 0.64 10.4 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain CMD PF02627.20 EEQ36698.1 - 7.4e-07 29.1 0.0 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Haem_degrading PF03928.14 EEQ36700.1 - 2e-32 111.8 0.0 2.5e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading PIR PF00399.19 EEQ36701.1 - 1.1e-20 72.7 102.6 0.00013 21.4 3.3 9.8 9 0 0 9 9 9 9 Yeast PIR protein repeat SEP PF08059.13 EEQ36701.1 - 0.047 14.3 3.3 20 5.8 0.3 4.4 2 1 3 5 5 5 0 SEP domain TFIIA PF03153.13 EEQ36701.1 - 0.066 13.2 28.9 0.087 12.8 28.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chitin_synth_2 PF03142.15 EEQ36701.1 - 0.084 11.5 3.8 0.096 11.3 2.7 1.5 1 1 0 1 1 1 0 Chitin synthase DUF1357 PF07094.11 EEQ36702.1 - 0.056 13.5 0.1 0.068 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1357) Say1_Mug180 PF10340.9 EEQ36703.1 - 1.8e-23 83.0 0.0 2.6e-21 75.9 0.0 2.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EEQ36703.1 - 6.2e-11 42.6 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold FtsJ PF01728.19 EEQ36705.1 - 1.6e-54 184.7 0.0 2e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EEQ36705.1 - 0.0022 17.8 0.1 0.0046 16.7 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Mpp10 PF04006.12 EEQ36706.1 - 3.9e-130 435.2 79.5 4.8e-130 434.9 79.5 1.0 1 0 0 1 1 1 1 Mpp10 protein DnaI_N PF07319.11 EEQ36706.1 - 0.017 15.8 0.5 0.017 15.8 0.5 2.6 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus IFP_35_N PF07334.13 EEQ36706.1 - 0.022 14.8 0.4 0.022 14.8 0.4 2.7 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF2401 PF10287.9 EEQ36708.1 - 1.4e-82 276.8 2.4 1.4e-82 276.8 2.4 1.7 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EEQ36708.1 - 9.4e-21 74.0 0.1 2.5e-20 72.6 0.1 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) TPR_MLP1_2 PF07926.12 EEQ36709.1 - 0.0013 18.8 13.0 0.0013 18.8 13.0 2.6 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein OmpH PF03938.14 EEQ36709.1 - 0.009 16.3 26.7 0.31 11.4 3.6 2.7 1 1 1 2 2 2 1 Outer membrane protein (OmpH-like) Baculo_PEP_C PF04513.12 EEQ36709.1 - 0.054 13.5 8.7 8.8 6.4 0.3 3.2 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vac_Fusion PF02346.16 EEQ36709.1 - 0.06 13.0 0.9 0.32 10.6 0.9 2.4 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 CALCOCO1 PF07888.11 EEQ36709.1 - 0.077 11.8 29.3 0.82 8.5 29.1 2.0 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 EEQ36709.1 - 0.32 11.0 20.7 0.36 10.9 4.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 EEQ36709.1 - 0.37 10.2 31.9 0.72 9.3 9.1 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 Spc7 PF08317.11 EEQ36709.1 - 0.42 9.4 31.1 0.042 12.7 6.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EEQ36709.1 - 0.58 9.5 32.9 0.22 10.8 17.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.19 EEQ36709.1 - 0.96 7.3 18.3 1.6 6.6 18.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tup_N PF08581.10 EEQ36709.1 - 1.4 9.3 28.9 0.27 11.6 6.0 4.3 1 1 4 5 5 5 0 Tup N-terminal BRE1 PF08647.11 EEQ36709.1 - 2.9 8.0 28.6 0.4 10.8 12.4 2.8 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Apolipoprotein PF01442.18 EEQ36709.1 - 3.8 7.3 23.3 0.17 11.7 3.8 2.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Fez1 PF06818.15 EEQ36709.1 - 4.1 7.8 30.1 3.1 8.2 20.5 2.3 1 1 1 2 2 2 0 Fez1 BST2 PF16716.5 EEQ36709.1 - 5 7.8 23.9 2.9 8.5 8.7 3.7 2 2 2 4 4 4 0 Bone marrow stromal antigen 2 ATG16 PF08614.11 EEQ36709.1 - 6.8 6.9 27.3 0.7 10.1 10.4 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ADIP PF11559.8 EEQ36709.1 - 9.6 6.3 32.6 5 7.2 20.9 3.2 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.6 EEQ36709.1 - 10 6.5 20.3 2.3 8.6 1.5 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) Flavin_Reduct PF01613.18 EEQ36710.1 - 1.5e-24 86.8 0.0 2.4e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain Peptidase_C50 PF03568.17 EEQ36711.1 - 1.6e-104 350.2 0.0 5.4e-104 348.4 0.0 2.0 1 0 0 1 1 1 1 Peptidase family C50 Carn_acyltransf PF00755.20 EEQ36711.1 - 3.3e-05 22.7 0.2 0.00088 18.0 0.0 2.5 2 0 0 2 2 2 1 Choline/Carnitine o-acyltransferase Peptidase_C25 PF01364.18 EEQ36711.1 - 0.058 12.6 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C25 MVP_shoulder PF11978.8 EEQ36711.1 - 5.4 7.1 5.6 12 5.9 0.3 3.3 4 0 0 4 4 4 0 Shoulder domain zf-MYND PF01753.18 EEQ36712.1 - 8.6e-07 28.9 19.8 1.9e-06 27.9 19.8 1.6 1 0 0 1 1 1 1 MYND finger DUF3150 PF11348.8 EEQ36712.1 - 0.012 14.9 0.4 0.019 14.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) DUF3074 PF11274.8 EEQ36713.1 - 6.5e-29 101.2 0.0 8.2e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) DUF1712 PF08217.11 EEQ36714.1 - 1.1e-07 30.8 0.0 0.022 13.2 0.0 3.7 2 2 0 3 3 3 2 Fungal domain of unknown function (DUF1712) AAA PF00004.29 EEQ36715.1 - 1e-10 42.1 1.1 2.5e-10 40.9 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEQ36715.1 - 2.6e-06 27.5 0.1 2.5e-05 24.3 0.1 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EEQ36715.1 - 0.00016 22.1 0.0 0.0012 19.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ36715.1 - 0.0003 21.1 0.0 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEQ36715.1 - 0.0014 18.5 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_14 PF13173.6 EEQ36715.1 - 0.0016 18.5 0.0 0.0083 16.2 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EEQ36715.1 - 0.0027 17.4 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EEQ36715.1 - 0.0096 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_6 PF12774.7 EEQ36715.1 - 0.012 14.6 0.0 0.027 13.4 0.0 1.5 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_33 PF13671.6 EEQ36715.1 - 0.032 14.4 1.5 0.086 13.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EEQ36715.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2184 PF09950.9 EEQ36715.1 - 0.063 12.7 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) AAA_assoc_2 PF16193.5 EEQ36715.1 - 0.074 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain RNA_helicase PF00910.22 EEQ36715.1 - 0.079 13.3 0.0 0.41 11.0 0.0 2.2 3 0 0 3 3 1 0 RNA helicase AAA_11 PF13086.6 EEQ36715.1 - 0.1 12.4 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EEQ36715.1 - 0.11 12.3 0.2 8.8 6.1 0.1 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase TIP49 PF06068.13 EEQ36715.1 - 0.17 11.0 0.0 0.37 9.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 EEQ36715.1 - 1.1 9.8 2.8 2.7 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain CRAL_TRIO PF00650.20 EEQ36716.1 - 4.2e-36 124.1 0.0 7.1e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ36716.1 - 2.9e-09 37.0 0.1 6.9e-09 35.8 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEQ36716.1 - 0.027 14.6 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EEQ36716.1 - 0.1 12.8 0.1 0.28 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) RasGAP PF00616.19 EEQ36717.1 - 5.1e-58 196.2 5.5 1.1e-57 195.1 5.5 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EEQ36717.1 - 2.1e-05 24.7 1.1 4.5e-05 23.7 0.2 2.0 2 0 0 2 2 2 1 C2 domain AAA_12 PF13087.6 EEQ36718.1 - 5.4e-58 195.9 0.0 1.2e-57 194.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain UPF1_Zn_bind PF09416.10 EEQ36718.1 - 4e-56 189.2 1.4 7.6e-56 188.3 0.8 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_11 PF13086.6 EEQ36718.1 - 1.8e-48 165.6 2.5 1e-25 91.0 0.2 2.3 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EEQ36718.1 - 5.9e-16 58.8 3.4 4e-15 56.0 3.4 2.2 1 1 0 1 1 1 1 AAA domain DUF5599 PF18141.1 EEQ36718.1 - 2.6e-13 50.0 0.0 6.9e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_19 PF13245.6 EEQ36718.1 - 5.5e-12 46.3 0.1 1.5e-11 44.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EEQ36718.1 - 4.6e-06 26.6 0.0 0.12 12.1 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EEQ36718.1 - 0.00055 19.3 0.1 0.027 13.7 0.0 3.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EEQ36718.1 - 0.0013 18.7 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 Helicase ResIII PF04851.15 EEQ36718.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PIF1 PF05970.14 EEQ36718.1 - 0.0038 16.5 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase PhoH PF02562.16 EEQ36718.1 - 0.0059 16.1 0.0 0.039 13.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 EEQ36718.1 - 0.0079 16.6 2.8 0.013 15.9 0.4 2.3 2 0 0 2 2 2 1 AAA ATPase domain UvrD_C_2 PF13538.6 EEQ36718.1 - 0.011 15.5 0.0 0.16 11.8 0.0 2.6 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.29 EEQ36718.1 - 0.014 15.8 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 EEQ36718.1 - 0.042 13.4 0.3 1.1 8.7 0.1 2.2 1 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EEQ36718.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NLRC4_HD PF17889.1 EEQ36718.1 - 0.046 14.1 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 NLRC4 helical domain T2SSE PF00437.20 EEQ36718.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.14 EEQ36718.1 - 0.11 12.4 0.2 0.27 11.2 0.2 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain IstB_IS21 PF01695.17 EEQ36718.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PT PF04886.12 EEQ36719.1 - 0.13 11.8 5.3 1.3 8.6 5.3 2.5 1 1 0 1 1 1 0 PT repeat UQ_con PF00179.26 EEQ36724.1 - 3.8e-45 153.0 0.0 4.5e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ36724.1 - 0.0023 17.6 0.0 0.0031 17.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EEQ36724.1 - 0.051 13.5 0.0 0.1 12.4 0.0 1.6 1 1 0 1 1 1 0 UEV domain CRCB PF02537.15 EEQ36725.1 - 2.8e-30 104.5 19.1 2e-17 63.3 6.1 2.3 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Mito_carr PF00153.27 EEQ36726.1 - 5.1e-68 225.1 6.1 1.2e-23 82.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ACAS_N PF16177.5 EEQ36726.1 - 0.17 11.9 1.6 0.33 10.9 1.6 1.4 1 0 0 1 1 1 0 Acetyl-coenzyme A synthetase N-terminus SAM_decarbox PF01536.16 EEQ36727.1 - 1.3e-126 422.5 0.0 1.5e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Pkinase PF00069.25 EEQ36728.1 - 2e-65 220.8 0.0 2.7e-65 220.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36728.1 - 4.8e-35 121.1 0.0 7e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ36728.1 - 7.2e-07 28.8 0.0 2.2e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ36728.1 - 0.001 17.9 0.0 0.002 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EEQ36728.1 - 0.0012 18.5 0.0 0.73 9.4 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_C PF00433.24 EEQ36728.1 - 0.0049 17.5 0.2 0.014 16.1 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 EEQ36728.1 - 0.11 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ36728.1 - 0.15 12.0 0.1 1.7 8.5 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Dynamin_M PF01031.20 EEQ36729.1 - 1.6e-101 339.3 0.2 3.3e-101 338.3 0.2 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EEQ36729.1 - 1.4e-55 187.9 1.2 2.2e-55 187.3 0.1 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EEQ36729.1 - 3.6e-29 100.8 6.6 3.6e-29 100.8 6.6 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EEQ36729.1 - 6.8e-05 22.9 0.2 0.00037 20.5 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ36729.1 - 0.029 14.8 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Macro PF01661.21 EEQ36730.1 - 3e-23 82.1 0.0 3.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Macro domain TruB_N PF01509.18 EEQ36732.1 - 9.3e-42 142.9 0.1 9.3e-42 142.9 0.1 2.1 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EEQ36732.1 - 0.00042 20.4 0.0 0.005 17.0 0.0 2.4 2 0 0 2 2 2 1 tRNA pseudouridylate synthase B C-terminal domain Propeptide_C1 PF08127.13 EEQ36732.1 - 0.19 11.6 0.9 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Peptidase family C1 propeptide RPN2_C PF18004.1 EEQ36732.1 - 0.78 9.6 12.9 1.7 8.5 12.9 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Erf4 PF10256.9 EEQ36733.1 - 1.2e-27 96.3 0.0 1.7e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family PPR_2 PF13041.6 EEQ36734.1 - 6.4e-15 55.1 11.4 0.00097 19.3 0.2 7.0 7 1 1 8 8 8 4 PPR repeat family PPR_3 PF13812.6 EEQ36734.1 - 1.5e-07 31.4 5.3 0.085 12.9 0.0 5.3 5 2 2 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 EEQ36734.1 - 0.0025 17.9 6.9 19 5.8 0.0 8.2 11 0 0 11 11 11 1 PPR repeat RPM2 PF08579.11 EEQ36734.1 - 0.042 14.3 0.5 0.34 11.3 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Cyto_heme_lyase PF01265.17 EEQ36735.1 - 2.3e-95 319.6 9.9 5.6e-94 315.0 9.9 2.5 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase OTU PF02338.19 EEQ36737.1 - 5.1e-24 85.2 0.3 1.3e-23 83.9 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EEQ36737.1 - 3.5e-05 23.4 1.3 0.00012 21.7 0.1 2.3 2 1 0 2 2 2 1 Peptidase C65 Otubain DUF603 PF04645.12 EEQ36737.1 - 0.054 13.2 0.6 0.15 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF603 PHM7_cyt PF14703.6 EEQ36737.1 - 0.32 11.2 8.0 0.3 11.3 6.6 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Cep57_MT_bd PF06657.13 EEQ36737.1 - 0.84 10.1 7.0 0.29 11.6 3.0 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 EEQ36737.1 - 2.9 7.2 15.7 4.1 6.7 15.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) T2SSM PF04612.12 EEQ36737.1 - 2.9 7.9 10.1 0.88 9.6 1.8 2.5 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Cyclin_N PF00134.23 EEQ36738.1 - 5.5e-37 126.4 0.8 1e-36 125.5 0.8 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cupin_8 PF13621.6 EEQ36739.1 - 2.1e-39 135.8 0.1 2.3e-37 129.1 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EEQ36739.1 - 6.3e-08 32.4 0.1 4.1e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 Cupin superfamily protein Cupin_2 PF07883.11 EEQ36739.1 - 0.11 12.2 0.0 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Cupin domain BUD22 PF09073.10 EEQ36739.1 - 0.51 9.6 8.3 0.76 9.1 8.3 1.2 1 0 0 1 1 1 0 BUD22 ETF_QO PF05187.13 EEQ36741.1 - 9.2e-46 154.3 0.5 1.5e-45 153.6 0.5 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EEQ36741.1 - 5.1e-09 36.2 0.0 5.1e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EEQ36741.1 - 3.5e-08 32.9 0.2 0.00062 19.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EEQ36741.1 - 4.7e-06 26.7 0.0 1.5e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ36741.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ36741.1 - 0.00017 20.4 0.0 0.00076 18.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EEQ36741.1 - 0.00032 20.0 0.0 0.0095 15.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 EEQ36741.1 - 0.0017 17.7 0.2 0.0026 17.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EEQ36741.1 - 0.0025 17.1 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 EEQ36741.1 - 0.0075 16.8 0.7 0.019 15.5 0.7 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 EEQ36741.1 - 0.011 15.7 0.1 0.023 14.7 0.1 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EEQ36741.1 - 0.012 14.7 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 EEQ36741.1 - 0.018 15.6 0.1 8.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ36741.1 - 0.018 13.9 0.0 0.51 9.1 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 EEQ36741.1 - 0.064 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EEQ36741.1 - 0.075 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EEQ36741.1 - 0.083 12.2 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ferric_reduct PF01794.19 EEQ36742.1 - 2.5e-22 79.3 15.1 6.4e-22 78.0 15.1 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EEQ36742.1 - 5.1e-18 65.2 0.0 9.9e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EEQ36742.1 - 7e-17 62.0 0.0 1.3e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain CDC24 PF06395.11 EEQ36743.1 - 1.1e-34 118.6 0.6 5.9e-34 116.2 0.2 2.3 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 EEQ36743.1 - 1.1e-31 110.4 0.3 1.1e-31 110.4 0.3 2.1 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.6 EEQ36743.1 - 6.7e-31 107.1 0.3 6.7e-31 107.1 0.3 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PB1 PF00564.24 EEQ36743.1 - 2.5e-07 30.5 0.1 7.5e-07 29.0 0.1 1.9 1 0 0 1 1 1 1 PB1 domain PH PF00169.29 EEQ36743.1 - 0.023 15.2 0.3 0.093 13.2 0.3 2.1 1 1 0 1 1 1 0 PH domain WD40 PF00400.32 EEQ36744.1 - 6.2e-25 87.0 5.9 6.9e-08 33.0 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36744.1 - 5.6e-16 58.6 0.0 0.011 16.1 0.0 5.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EEQ36744.1 - 3e-05 23.2 0.0 0.0038 16.3 0.0 2.0 2 0 0 2 2 2 2 Coatomer WD associated region BBS2_Mid PF14783.6 EEQ36744.1 - 0.021 14.9 0.0 0.088 12.9 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 EEQ36744.1 - 0.023 13.2 0.0 0.035 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Hira PF07569.11 EEQ36744.1 - 0.071 12.8 0.0 18 5.0 0.0 2.8 3 0 0 3 3 3 0 TUP1-like enhancer of split ELYS-bb PF16687.5 EEQ36744.1 - 0.14 10.7 0.0 2.4 6.7 0.0 2.4 1 1 2 3 3 3 0 beta-propeller of ELYS nucleoporin COPIIcoated_ERV PF07970.12 EEQ36745.1 - 3.1e-71 239.8 0.0 3.8e-71 239.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EEQ36745.1 - 5.9e-28 97.0 0.6 2.7e-27 94.9 0.2 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MRP-L46 PF11788.8 EEQ36746.1 - 3.4e-40 137.5 3.8 4.8e-40 137.0 3.8 1.2 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 RRM_1 PF00076.22 EEQ36747.1 - 1.5e-06 27.9 0.0 2.9e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Collagen PF01391.18 EEQ36747.1 - 0.00039 20.1 15.2 0.00039 20.1 15.2 3.3 3 0 0 3 3 3 1 Collagen triple helix repeat (20 copies) CTD_bind PF04818.13 EEQ36747.1 - 0.0061 17.4 0.0 0.019 15.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 EEQ36747.1 - 0.028 14.6 0.0 0.13 12.4 0.0 2.1 3 0 0 3 3 3 0 RNA recognition motif CTK3 PF12243.8 EEQ36747.1 - 0.21 11.6 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Peptidase_M41 PF01434.18 EEQ36748.1 - 1.3e-59 201.3 0.1 2.5e-59 200.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EEQ36748.1 - 4.3e-41 140.4 0.0 1.2e-40 138.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ36748.1 - 2.7e-06 27.1 0.0 6.7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ36748.1 - 2.6e-05 24.7 0.4 0.00017 22.0 0.4 2.2 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EEQ36748.1 - 4.4e-05 22.9 0.0 0.00011 21.6 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 EEQ36748.1 - 0.0004 20.2 0.1 0.015 15.0 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ36748.1 - 0.00096 19.4 0.0 0.12 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EEQ36748.1 - 0.0015 18.5 0.1 0.0079 16.2 0.1 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ36748.1 - 0.017 15.2 0.2 0.25 11.5 0.0 3.0 3 1 0 3 3 3 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EEQ36748.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEQ36748.1 - 0.043 13.2 0.2 0.11 11.9 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EEQ36748.1 - 0.072 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EEQ36748.1 - 0.084 12.2 0.1 0.56 9.5 0.1 2.1 2 0 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 EEQ36748.1 - 0.1 12.3 0.2 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EEQ36748.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ36748.1 - 0.15 11.6 0.1 0.86 9.1 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EEQ36748.1 - 0.15 11.6 0.9 1.4 8.5 0.6 2.3 1 1 0 2 2 2 0 AAA domain SpoU_sub_bind PF08032.12 EEQ36748.1 - 0.16 12.2 0.1 26 5.2 0.0 2.8 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Cnd2 PF05786.14 EEQ36749.1 - 1.7e-159 533.0 37.3 2.5e-159 532.4 37.3 1.2 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EEQ36749.1 - 0.0048 17.1 0.1 0.0048 17.1 0.1 3.7 4 0 0 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Gag_p15 PF08723.10 EEQ36749.1 - 0.026 14.7 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Gag protein p15 DUF4602 PF15375.6 EEQ36750.1 - 5 7.5 31.9 3.1e+02 1.6 31.5 3.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4602) His_biosynth PF00977.21 EEQ36751.1 - 6.8e-26 91.1 0.0 8.8e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein RNA_pol_A_bac PF01000.26 EEQ36752.1 - 2.2e-30 105.3 0.0 3.8e-30 104.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EEQ36752.1 - 2.6e-18 65.2 0.0 3.3e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1770 PF08589.10 EEQ36753.1 - 4.6e-05 24.3 0.1 9e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1770) PilO PF04350.13 EEQ36754.1 - 4 7.6 9.3 0.95 9.6 3.9 2.4 1 1 1 2 2 2 0 Pilus assembly protein, PilO RabGAP-TBC PF00566.18 EEQ36755.1 - 2.6e-52 177.6 0.9 5.7e-52 176.5 0.9 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 EEQ36755.1 - 2.5e-09 37.0 0.0 9.8e-09 35.1 0.0 2.1 1 0 0 1 1 1 1 GRAM domain Vps36_ESCRT-II PF11605.8 EEQ36755.1 - 0.006 16.7 0.1 0.034 14.3 0.0 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 Nop53 PF07767.11 EEQ36755.1 - 0.13 11.7 4.5 0.24 10.7 4.5 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ANAPC8 PF04049.13 EEQ36755.1 - 0.75 9.8 4.1 0.81 9.7 0.0 2.9 3 1 1 4 4 4 0 Anaphase promoting complex subunit 8 / Cdc23 Fmp27_WPPW PF10359.9 EEQ36756.1 - 3.2e-134 448.4 9.7 3.2e-134 448.4 9.7 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 EEQ36756.1 - 6.6e-125 417.7 21.6 6.6e-125 417.7 21.6 3.4 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27 PF10344.9 EEQ36756.1 - 2.3e-68 231.2 46.8 2.3e-68 231.2 46.8 2.3 2 0 0 2 2 2 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.9 EEQ36756.1 - 2.2e-53 180.6 0.0 7.4e-53 178.8 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EEQ36756.1 - 5.6e-42 143.3 0.6 5.6e-42 143.3 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EEQ36756.1 - 2.1e-17 63.7 0.0 2.6e-16 60.2 0.0 3.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2682 PF10909.8 EEQ36756.1 - 0.047 14.2 1.1 0.29 11.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) Laminin_II PF06009.12 EEQ36756.1 - 3.1 7.8 8.6 1.9 8.5 0.4 3.5 3 0 0 3 3 3 0 Laminin Domain II AAA PF00004.29 EEQ36757.1 - 1.2e-45 155.2 0.1 3.3e-45 153.7 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EEQ36757.1 - 8.9e-10 38.4 0.2 5.6e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EEQ36757.1 - 9.2e-09 35.6 0.0 1.8e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEQ36757.1 - 2.2e-08 34.6 0.1 3.1e-05 24.4 0.0 3.2 1 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EEQ36757.1 - 6.8e-08 32.6 0.1 2.7e-07 30.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ36757.1 - 2.3e-05 24.7 0.8 0.0028 17.9 0.8 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EEQ36757.1 - 7.3e-05 22.0 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 EEQ36757.1 - 0.00026 20.7 0.0 0.00059 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EEQ36757.1 - 0.00046 20.0 0.0 0.0017 18.1 0.0 2.0 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EEQ36757.1 - 0.00067 20.2 0.0 0.004 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EEQ36757.1 - 0.00087 19.2 0.0 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 EEQ36757.1 - 0.0011 19.1 0.0 0.0029 17.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EEQ36757.1 - 0.0021 18.3 0.0 0.0053 16.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EEQ36757.1 - 0.0021 17.6 0.1 0.014 14.9 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_3 PF07726.11 EEQ36757.1 - 0.0024 17.7 0.0 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EEQ36757.1 - 0.0042 16.8 0.7 0.014 15.1 0.0 2.3 3 1 0 3 3 2 1 AAA domain TsaE PF02367.17 EEQ36757.1 - 0.005 16.8 0.0 0.0096 15.9 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EEQ36757.1 - 0.0054 16.5 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEQ36757.1 - 0.0068 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EEQ36757.1 - 0.0069 15.6 0.1 0.019 14.2 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 EEQ36757.1 - 0.0076 15.7 0.0 0.51 9.7 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 EEQ36757.1 - 0.008 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EEQ36757.1 - 0.015 15.6 0.0 0.032 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ36757.1 - 0.016 15.1 0.3 0.12 12.3 0.1 2.3 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 EEQ36757.1 - 0.019 14.7 0.0 0.051 13.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EEQ36757.1 - 0.02 15.2 0.1 0.38 11.1 0.1 2.5 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 EEQ36757.1 - 0.025 14.3 0.2 0.3 10.8 0.0 2.4 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_11 PF13086.6 EEQ36757.1 - 0.043 13.6 0.1 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EEQ36757.1 - 0.044 13.7 1.3 0.51 10.2 0.0 2.6 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EEQ36757.1 - 0.073 12.4 0.2 0.94 8.8 0.0 2.3 2 0 0 2 2 2 0 KaiC Parvo_NS1 PF01057.17 EEQ36757.1 - 0.21 10.6 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EEQ36757.1 - 0.27 10.8 0.1 0.27 10.8 0.1 2.2 2 1 0 3 3 3 0 AAA domain AAA_23 PF13476.6 EEQ36757.1 - 0.59 10.6 3.4 2.5 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Glyco_transf_22 PF03901.17 EEQ36759.1 - 1.6e-64 218.6 34.7 2.1e-64 218.3 34.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Utp12 PF04003.12 EEQ36760.1 - 3.9e-24 85.0 2.8 3.9e-24 85.0 2.8 1.9 2 0 0 2 2 2 1 Dip2/Utp12 Family Ras PF00071.22 EEQ36761.1 - 1.6e-57 193.7 0.0 1.9e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ36761.1 - 4.8e-22 78.4 0.0 6.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ36761.1 - 5.3e-09 35.8 0.0 9.3e-09 35.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ36761.1 - 0.00092 18.8 0.0 0.0043 16.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEQ36761.1 - 0.0039 16.6 0.0 0.0051 16.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEQ36761.1 - 0.0072 16.4 0.0 0.015 15.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EEQ36761.1 - 0.011 15.2 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EEQ36761.1 - 0.037 13.9 0.0 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 EEQ36761.1 - 0.042 13.0 0.0 0.15 11.2 0.0 1.6 1 1 1 2 2 2 0 G-protein alpha subunit ABC_tran PF00005.27 EEQ36761.1 - 0.048 14.2 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EEQ36761.1 - 0.063 13.7 0.0 0.086 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain DUF3128 PF11326.8 EEQ36762.1 - 4.5e-26 91.0 0.9 4.5e-26 91.0 0.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3128) Amidohydro_1 PF01979.20 EEQ36764.1 - 3.5e-36 125.2 0.0 2.3e-17 63.3 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ36764.1 - 2.1e-15 57.2 0.1 4.3e-10 39.6 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family ADH_zinc_N PF00107.26 EEQ36765.1 - 5e-13 49.2 0.0 7.6e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ36765.1 - 0.00067 20.7 0.0 0.0015 19.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ36765.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Mpv17_PMP22 PF04117.12 EEQ36766.1 - 0.0012 19.0 1.6 0.0026 17.9 1.6 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF4731 PF15875.5 EEQ36766.1 - 0.11 12.7 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4731) Sugar_tr PF00083.24 EEQ36767.1 - 9.5e-88 295.0 26.0 1.2e-87 294.7 26.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36767.1 - 7.6e-14 51.4 44.1 1.2e-10 40.9 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.6 EEQ36767.1 - 0.0092 16.2 1.0 0.03 14.6 1.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4293) ArfGap PF01412.18 EEQ36768.1 - 8.1e-36 122.7 1.0 1.6e-35 121.7 0.1 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Tim44 PF04280.15 EEQ36769.1 - 5.5e-38 130.4 0.2 1.5e-37 129.0 0.2 1.8 1 0 0 1 1 1 1 Tim44-like domain Senescence PF06911.12 EEQ36769.1 - 0.002 18.5 1.8 0.0035 17.7 1.8 1.5 1 0 0 1 1 1 1 Senescence-associated protein OmpH PF03938.14 EEQ36769.1 - 0.017 15.5 1.7 0.017 15.5 1.7 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) MapZ_EC1 PF18041.1 EEQ36769.1 - 0.034 14.4 2.4 0.038 14.2 0.9 1.9 2 0 0 2 2 2 0 MapZ extracellular domain 1 Phycobilisome PF00502.19 EEQ36769.1 - 0.17 11.8 0.3 0.49 10.3 0.3 1.9 1 0 0 1 1 1 0 Phycobilisome protein FAD_binding_3 PF01494.19 EEQ36770.1 - 4.2e-21 75.6 0.0 7.7e-21 74.7 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EEQ36770.1 - 2.5e-06 26.8 0.0 5.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 EEQ36770.1 - 1.6e-05 25.0 0.0 3.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ36770.1 - 6.7e-05 22.6 0.0 0.01 15.4 0.0 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEQ36770.1 - 0.00017 22.1 0.0 0.0022 18.5 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EEQ36770.1 - 0.00028 20.8 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EEQ36770.1 - 0.00062 19.1 0.0 0.0022 17.3 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ36770.1 - 0.0053 15.7 0.1 1.4 7.7 0.0 2.5 3 0 0 3 3 3 2 Tryptophan halogenase GIDA PF01134.22 EEQ36770.1 - 0.0067 15.6 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EEQ36770.1 - 0.052 12.8 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EEQ36770.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EEQ36770.1 - 0.085 11.5 0.0 2.1 6.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EEQ36770.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EEQ36770.1 - 0.2 11.3 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Spc7 PF08317.11 EEQ36771.1 - 0.043 12.7 23.1 0.091 11.6 23.1 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein COG5 PF10392.9 EEQ36771.1 - 0.19 11.9 11.9 0.42 10.8 5.8 2.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF3381 PF11861.8 EEQ36771.1 - 0.19 11.5 15.6 0.4 10.4 15.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) AAA_23 PF13476.6 EEQ36771.1 - 0.36 11.3 14.3 1 9.8 14.3 1.8 1 0 0 1 1 1 0 AAA domain DHR10 PF18595.1 EEQ36771.1 - 0.98 9.5 24.8 0.34 11.0 3.5 2.7 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 EEQ36771.1 - 1.1 9.8 29.3 3.3 8.2 17.7 2.9 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 EEQ36771.1 - 1.4 7.4 13.3 2.4 6.7 13.3 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 EEQ36771.1 - 1.4 9.2 20.9 2.5 8.4 17.8 2.8 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Cnn_1N PF07989.11 EEQ36771.1 - 1.5 9.0 26.8 0.27 11.4 15.2 3.3 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 NBP1 PF08537.10 EEQ36771.1 - 1.5 8.1 15.0 2.4 7.5 15.0 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 ADIP PF11559.8 EEQ36771.1 - 1.8 8.6 26.3 0.5 10.4 10.9 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 EEQ36771.1 - 2.3 7.4 17.4 6.5 6.0 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) RabGAP-TBC PF00566.18 EEQ36771.1 - 2.4 7.7 8.7 0.04 13.6 1.0 2.1 2 2 0 2 2 2 0 Rab-GTPase-TBC domain YabA PF06156.13 EEQ36771.1 - 2.9 8.6 18.0 3.7 8.2 6.0 3.1 1 1 1 2 2 2 0 Initiation control protein YabA Fib_alpha PF08702.10 EEQ36771.1 - 4.4 7.5 14.2 16 5.7 14.2 2.0 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Nup54 PF13874.6 EEQ36771.1 - 5.7 7.0 19.0 0.52 10.4 8.9 2.7 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DivIC PF04977.15 EEQ36771.1 - 5.8 6.8 25.8 2.9 7.7 5.7 4.3 2 1 2 4 4 4 0 Septum formation initiator DUF4201 PF13870.6 EEQ36771.1 - 7 6.3 25.1 8.3 6.1 20.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) Med9 PF07544.13 EEQ36771.1 - 7.5 6.7 17.3 44 4.2 15.2 2.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_C48 PF02902.19 EEQ36772.1 - 2.6e-28 99.3 2.7 2.6e-28 99.3 2.7 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Serum_albumin PF00273.20 EEQ36772.1 - 0.087 12.6 2.2 0.16 11.7 0.5 2.2 2 0 0 2 2 2 0 Serum albumin family 4HBT PF03061.22 EEQ36773.1 - 2.2e-08 34.3 0.0 3.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily HSP9_HSP12 PF04119.12 EEQ36774.1 - 7.1e-21 74.4 5.4 7.9e-21 74.2 5.4 1.0 1 0 0 1 1 1 1 Heat shock protein 9/12 DUF2564 PF10819.8 EEQ36774.1 - 0.11 12.9 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Thymidylat_synt PF00303.19 EEQ36775.1 - 2.9e-112 374.2 0.0 3.3e-112 374.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Shugoshin_N PF07558.11 EEQ36776.1 - 7.1e-08 32.2 2.2 7.1e-08 32.2 2.2 1.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region DUF148 PF02520.17 EEQ36776.1 - 0.00088 19.4 0.8 0.0022 18.1 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF148 TPR_MLP1_2 PF07926.12 EEQ36776.1 - 0.26 11.3 0.2 0.26 11.3 0.2 3.5 4 0 0 4 4 4 0 TPR/MLP1/MLP2-like protein DASH_Dad2 PF08654.10 EEQ36777.1 - 1.2e-24 86.6 3.2 3.1e-24 85.2 3.2 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 EEQ36777.1 - 0.0036 17.1 1.1 0.0073 16.1 1.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF848 PF05852.11 EEQ36777.1 - 0.047 13.8 0.8 0.062 13.4 0.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Med9 PF07544.13 EEQ36777.1 - 0.05 13.7 3.0 0.085 13.0 3.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF334 PF03904.13 EEQ36777.1 - 0.081 12.5 1.4 0.11 12.0 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) SpoOE-like PF09388.10 EEQ36777.1 - 0.085 12.8 1.8 0.085 12.8 1.8 1.9 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein MukB PF04310.12 EEQ36777.1 - 0.12 12.1 1.0 0.21 11.4 1.0 1.3 1 1 0 1 1 1 0 MukB N-terminal Nucleoporin_N PF08801.11 EEQ36778.1 - 4.1e-53 180.7 0.2 6e-53 180.1 0.2 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EEQ36778.1 - 2e-35 122.7 24.7 5.2e-34 118.0 24.7 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Brix PF04427.18 EEQ36779.1 - 1.2e-37 129.9 1.0 1.7e-37 129.4 1.0 1.2 1 0 0 1 1 1 1 Brix domain Peptidase_M10_C PF08548.11 EEQ36779.1 - 0.37 10.7 1.9 0.65 9.9 0.1 2.1 3 0 0 3 3 3 0 Peptidase M10 serralysin C terminal Asp PF00026.23 EEQ36780.1 - 1.2e-63 215.4 4.6 1.2e-63 215.4 4.6 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ36780.1 - 3.2e-13 50.3 0.6 3.2e-13 50.3 0.6 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEQ36780.1 - 0.02 15.6 0.2 45 4.8 0.0 4.4 4 0 0 4 4 4 0 Aspartyl protease Pkinase PF00069.25 EEQ36782.1 - 1.5e-40 139.2 0.0 3.7e-36 124.8 0.0 3.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36782.1 - 6.5e-16 58.4 0.0 6.4e-13 48.6 0.0 2.8 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EEQ36782.1 - 0.0016 18.4 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ36782.1 - 0.042 13.2 0.0 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Bot1p PF12298.8 EEQ36783.1 - 3.2e-21 76.3 0.0 5.1e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein EMP24_GP25L PF01105.24 EEQ36784.1 - 3.9e-48 163.8 0.9 4.7e-48 163.6 0.9 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2569 PF10754.9 EEQ36784.1 - 0.027 14.9 0.1 0.058 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) RNA_pol_A_bac PF01000.26 EEQ36785.1 - 9.1e-29 100.1 0.0 1.7e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EEQ36785.1 - 2.1e-21 75.1 0.0 2.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1746 PF08508.10 EEQ36786.1 - 8.8e-29 100.2 1.1 1.3e-28 99.6 1.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Nrap_D5 PF17406.2 EEQ36787.1 - 2.3e-52 177.0 0.2 5.5e-52 175.8 0.2 1.6 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 EEQ36787.1 - 1.6e-50 171.4 0.1 2.8e-50 170.6 0.1 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 EEQ36787.1 - 9.9e-50 168.2 0.1 1.3e-47 161.3 0.0 2.7 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap PF03813.14 EEQ36787.1 - 1.4e-45 155.0 2.9 3.9e-45 153.6 2.9 1.8 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EEQ36787.1 - 8.5e-44 149.4 0.0 1.8e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EEQ36787.1 - 7.7e-24 84.4 0.0 2.4e-23 82.9 0.0 1.9 1 0 0 1 1 1 1 Nrap protein domain 6 Cwf_Cwc_15 PF04889.12 EEQ36787.1 - 8 6.1 10.0 13 5.4 10.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SQHop_cyclase_C PF13243.6 EEQ36788.1 - 7.7e-39 133.7 0.0 4.3e-37 127.9 0.0 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EEQ36788.1 - 5.5e-38 130.7 0.1 1.5e-33 116.2 0.0 3.2 2 1 1 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EEQ36788.1 - 1.5e-19 69.4 1.1 2.7e-06 27.0 0.0 4.3 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EEQ36788.1 - 0.018 14.4 0.0 5.7 6.2 0.0 3.7 3 1 1 4 4 4 0 Pectic acid lyase TED_complement PF07678.14 EEQ36788.1 - 0.064 12.3 0.0 0.35 9.9 0.0 2.2 2 0 0 2 2 2 0 A-macroglobulin TED domain Ribosomal_L27A PF00828.19 EEQ36789.1 - 1.4e-26 93.7 0.1 3.4e-26 92.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF3629 PF12302.8 EEQ36789.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) Sld7_C PF18596.1 EEQ36790.1 - 5e-25 87.5 0.1 7.3e-25 86.9 0.1 1.3 1 0 0 1 1 1 1 Sld7 C-terminal domain Sld7_N PF18636.1 EEQ36790.1 - 0.0002 21.7 0.0 0.00058 20.2 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Pkinase PF00069.25 EEQ36791.1 - 4.4e-59 200.0 0.0 5.1e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36791.1 - 6.7e-17 61.6 0.0 1.4e-16 60.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EEQ36791.1 - 2e-06 27.9 0.0 1e-05 25.6 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ36791.1 - 0.0049 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EEQ36791.1 - 0.035 12.9 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 EEQ36791.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like CH PF00307.31 EEQ36792.1 - 6.5e-22 77.8 0.5 9.5e-14 51.5 0.0 3.7 3 1 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EEQ36792.1 - 0.0042 16.9 0.5 1.8 8.4 0.2 3.2 2 1 0 2 2 2 2 CAMSAP CH domain DUF2340 PF10209.9 EEQ36793.1 - 1.7e-50 170.5 1.9 2e-50 170.3 1.9 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) SIL1 PF16782.5 EEQ36794.1 - 1.7e-75 254.0 3.7 2.8e-75 253.2 3.7 1.3 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Ferritin PF00210.24 EEQ36794.1 - 0.0001 22.3 0.1 0.0002 21.3 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain PI_PP_C PF18365.1 EEQ36794.1 - 0.018 15.0 0.1 0.08 12.9 0.0 2.0 1 1 0 1 1 1 0 Phosphoinositide phosphatase C-terminal domain GSH_synth_ATP PF03917.17 EEQ36795.1 - 1.2e-130 435.7 0.5 1.3e-130 435.5 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EEQ36795.1 - 2.5e-32 111.4 0.1 6.1e-32 110.1 0.1 1.7 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EI24 PF07264.11 EEQ36796.1 - 4.9e-05 23.6 1.4 6.6e-05 23.2 1.4 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HAD_2 PF13419.6 EEQ36797.1 - 0.0035 17.5 0.1 0.0061 16.7 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.20 EEQ36798.1 - 8.9e-80 268.1 0.5 1.3e-79 267.5 0.5 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ36798.1 - 0.00044 20.2 0.2 0.00082 19.3 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEQ36798.1 - 0.079 12.4 0.7 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) PucR PF07905.11 EEQ36798.1 - 0.088 13.1 0.0 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family ATP-synt_B PF00430.18 EEQ36798.1 - 0.097 12.8 9.1 0.22 11.6 9.1 1.5 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) ISG65-75 PF11727.8 EEQ36798.1 - 0.15 11.2 4.3 0.29 10.3 4.3 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein zf-CCCH_2 PF14608.6 EEQ36799.1 - 2.5e-18 65.8 77.1 0.00022 21.6 6.2 7.4 7 0 0 7 7 7 6 RNA-binding, Nab2-type zinc finger Cpn60_TCP1 PF00118.24 EEQ36800.1 - 1.4e-142 475.8 12.5 1.6e-142 475.6 12.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_S5 PF00333.20 EEQ36801.1 - 1.1e-26 92.6 2.9 2.8e-26 91.3 2.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EEQ36801.1 - 6.2e-23 80.0 0.1 1e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain CoA_binding_3 PF13727.6 EEQ36801.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 CoA-binding domain DUF883 PF05957.13 EEQ36802.1 - 0.021 15.4 3.6 0.04 14.5 3.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF5353 PF17304.2 EEQ36802.1 - 0.053 13.3 0.4 0.13 12.0 0.4 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5353) Globin PF00042.22 EEQ36805.1 - 2e-06 28.3 0.0 7.5e-06 26.5 0.0 1.9 1 1 0 1 1 1 1 Globin FCP1_C PF09309.10 EEQ36805.1 - 0.1 12.5 0.2 0.29 11.0 0.1 1.7 1 1 1 2 2 2 0 FCP1, C-terminal TINF2_N PF14973.6 EEQ36805.1 - 0.22 11.9 1.3 0.36 11.2 0.7 1.6 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus EXOSC1 PF10447.9 EEQ36808.1 - 3.9e-37 127.2 0.0 6.2e-37 126.5 0.0 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 CSD2 PF17876.1 EEQ36808.1 - 0.051 13.7 0.0 0.32 11.2 0.0 2.1 2 0 0 2 2 2 0 Cold shock domain CRAL_TRIO PF00650.20 EEQ36809.1 - 3.8e-40 137.2 0.0 5.1e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ36809.1 - 4.6e-17 61.9 1.1 1e-16 60.8 1.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Elongin_A PF06881.11 EEQ36810.1 - 1e-25 90.3 0.0 2.5e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A RNase_P_p30 PF01876.16 EEQ36811.1 - 1.7e-59 200.9 0.0 2.1e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit p30 zf-AN1 PF01428.16 EEQ36812.1 - 3.3e-10 40.0 9.1 4.9e-10 39.4 9.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger C5HCH PF17982.1 EEQ36812.1 - 0.66 10.2 5.7 1.2 9.3 5.7 1.4 1 0 0 1 1 1 0 NSD Cys-His rich domain Pkinase PF00069.25 EEQ36813.1 - 3.9e-25 88.7 0.0 6.3e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36813.1 - 2.7e-12 46.5 0.0 4.9e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ36813.1 - 2.6e-08 33.1 0.0 2.6e-08 33.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EEQ36813.1 - 0.011 15.7 0.1 0.41 10.5 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family PIP49_C PF12260.8 EEQ36813.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Pre-PUA PF17832.1 EEQ36815.1 - 0.074 13.8 0.6 1.2 9.9 0.1 2.8 3 0 0 3 3 3 0 Pre-PUA-like domain Methyltransf_25 PF13649.6 EEQ36816.1 - 9.9e-15 55.0 0.0 2.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ36816.1 - 1.7e-14 54.0 0.0 2.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ36816.1 - 2.7e-14 53.2 0.0 4.4e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ36816.1 - 4.9e-14 52.8 0.0 1.2e-13 51.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ36816.1 - 1.8e-12 47.8 0.0 3.4e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ36816.1 - 1.3e-07 31.2 0.0 1.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EEQ36816.1 - 4.7e-06 26.3 0.0 9.3e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EEQ36816.1 - 0.0014 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 EEQ36816.1 - 0.025 13.7 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent DUF2194 PF09960.9 EEQ36816.1 - 0.035 12.5 0.0 0.045 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) DUF938 PF06080.12 EEQ36816.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CmcI PF04989.12 EEQ36816.1 - 0.056 13.1 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_4 PF02390.17 EEQ36816.1 - 0.068 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 EEQ36816.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UQ_con PF00179.26 EEQ36817.1 - 3.4e-22 78.6 0.0 4.8e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEQ36817.1 - 0.12 12.7 2.0 0.27 11.5 1.4 1.9 1 1 0 1 1 1 0 RWD domain Sel1 PF08238.12 EEQ36818.1 - 3.8e-44 148.1 25.6 9.8e-08 32.4 0.2 8.3 8 0 0 8 8 8 7 Sel1 repeat HTH_24 PF13412.6 EEQ36818.1 - 0.16 11.6 0.1 26 4.5 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Kinesin PF00225.23 EEQ36821.1 - 8.9e-117 389.7 0.0 1.6e-116 388.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ36821.1 - 3.2e-25 88.8 0.1 1.5e-24 86.6 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Exonuc_VII_L PF02601.15 EEQ36821.1 - 0.057 13.0 12.4 1.2 8.6 7.6 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit SAB PF04382.13 EEQ36821.1 - 0.083 13.0 0.4 0.24 11.5 0.4 1.8 1 0 0 1 1 1 0 SAB domain HD PF01966.22 EEQ36821.1 - 0.1 12.8 0.0 0.37 11.0 0.0 1.9 1 0 0 1 1 1 0 HD domain DUF5340 PF17275.2 EEQ36821.1 - 0.14 12.3 3.8 0.17 12.0 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5340) HxlR PF01638.17 EEQ36821.1 - 0.19 11.6 2.2 0.39 10.6 0.1 2.6 3 0 0 3 3 3 0 HxlR-like helix-turn-helix DUF4208 PF13907.6 EEQ36821.1 - 0.26 11.8 5.5 3.3 8.2 2.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4208) Baculo_PEP_C PF04513.12 EEQ36821.1 - 0.27 11.3 6.3 1 9.4 0.5 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Stathmin PF00836.19 EEQ36821.1 - 0.28 11.2 5.3 1 9.3 5.3 2.0 1 0 0 1 1 1 0 Stathmin family DUF4615 PF15393.6 EEQ36821.1 - 5.5 7.6 9.4 1.1 9.8 4.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Apolipoprotein PF01442.18 EEQ36821.1 - 8.8 6.1 11.6 0.77 9.6 3.8 2.6 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain SGTA_dimer PF16546.5 EEQ36822.1 - 3.5e-23 81.2 2.6 8.8e-23 79.9 2.6 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EEQ36822.1 - 3.8e-15 55.0 4.0 2.3e-05 24.0 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ36822.1 - 1.4e-12 46.7 6.2 0.0032 17.5 0.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ36822.1 - 4.8e-12 45.3 4.6 1.3e-06 28.0 0.4 3.2 1 1 2 3 3 3 2 TPR repeat TPR_17 PF13431.6 EEQ36822.1 - 1.6e-06 28.1 6.8 0.009 16.3 0.4 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ36822.1 - 7.1e-06 25.7 0.6 0.89 9.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ36822.1 - 2.3e-05 24.2 11.3 0.0095 16.1 0.7 4.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36822.1 - 3.9e-05 24.1 4.6 0.058 14.2 1.0 3.9 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ36822.1 - 4.6e-05 24.0 5.4 0.0013 19.3 3.6 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat STI1 PF17830.1 EEQ36822.1 - 0.00013 21.9 9.1 0.00019 21.3 4.8 2.6 3 0 0 3 3 3 1 STI1 domain BTAD PF03704.17 EEQ36822.1 - 0.00025 21.5 3.7 0.0028 18.1 0.6 2.5 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_19 PF14559.6 EEQ36822.1 - 0.0014 19.1 6.2 0.046 14.2 0.8 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ36822.1 - 0.0015 18.8 6.9 0.13 12.5 1.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ36822.1 - 0.0031 17.3 4.4 1.1 9.3 0.5 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ36822.1 - 0.027 14.6 0.2 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF627 PF04781.12 EEQ36822.1 - 0.095 12.7 3.3 0.1 12.6 1.6 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF627) XPC-binding PF09280.11 EEQ36822.1 - 2.6 7.8 8.8 2.2 8.1 2.4 2.4 2 0 0 2 2 2 0 XPC-binding domain TPR_6 PF13174.6 EEQ36822.1 - 3.4 8.5 7.3 2.6 8.9 1.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat VPS9 PF02204.18 EEQ36823.1 - 6e-13 48.9 0.1 2.6e-12 46.9 0.1 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ribo_biogen_C PF04034.13 EEQ36824.1 - 2.1e-51 172.9 0.1 3.1e-51 172.4 0.1 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EEQ36824.1 - 4.8e-16 58.3 0.4 8.7e-16 57.5 0.4 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Ribonuc_red_sm PF00268.21 EEQ36825.1 - 1.6e-122 408.3 1.9 2.1e-122 407.9 1.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Sugar_tr PF00083.24 EEQ36827.1 - 7.4e-73 245.9 27.3 8.1e-70 235.9 27.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36827.1 - 4.9e-22 78.3 30.2 4.9e-22 78.3 30.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ36827.1 - 5.7e-06 25.9 8.6 5.7e-06 25.9 8.6 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4191 PF13829.6 EEQ36827.1 - 3.6 6.9 5.3 0.54 9.5 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) PI-PLC-X PF00388.19 EEQ36828.1 - 2.5e-18 66.1 0.0 4.1e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain She9_MDM33 PF05546.11 EEQ36829.1 - 8.5e-80 267.2 10.4 8.5e-80 267.2 10.4 1.5 2 0 0 2 2 2 1 She9 / Mdm33 family Spc7 PF08317.11 EEQ36829.1 - 0.0071 15.3 18.6 0.022 13.7 15.3 2.3 2 0 0 2 2 2 1 Spc7 kinetochore protein DUF4381 PF14316.6 EEQ36829.1 - 0.91 9.8 4.6 0.93 9.7 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) DUF2524 PF10732.9 EEQ36829.1 - 0.98 9.8 12.1 0.9 9.9 1.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2524) Apt1 PF10351.9 EEQ36830.1 - 0.18 10.6 16.6 0.24 10.2 16.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FKBP_C PF00254.28 EEQ36831.1 - 1.6e-27 95.7 0.1 1.6e-27 95.7 0.1 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EEQ36831.1 - 4.2e-21 75.5 8.5 4.2e-21 75.5 8.5 2.9 2 2 0 2 2 2 1 Nucleoplasmin-like domain F1F0-ATPsyn_F PF10791.9 EEQ36831.1 - 1.8 9.1 3.3 28 5.3 2.3 2.5 2 0 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi DUF4045 PF13254.6 EEQ36831.1 - 4.3 6.9 33.7 4 7.0 20.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Presenilin PF01080.17 EEQ36831.1 - 4.3 6.0 30.1 2.5 6.8 15.5 2.1 2 0 0 2 2 2 0 Presenilin SOBP PF15279.6 EEQ36831.1 - 8.2 6.9 10.5 2.4 8.7 6.6 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein CCSAP PF15748.5 EEQ36831.1 - 8.3 6.5 35.0 3.7 7.7 18.9 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated C2 PF00168.30 EEQ36832.1 - 3.5e-60 200.7 2.1 2.9e-17 62.8 0.0 6.4 6 0 0 6 6 6 5 C2 domain Ribosomal_S3Ae PF01015.18 EEQ36834.1 - 2.3e-85 285.2 3.3 2.8e-85 285.0 3.3 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EEQ36834.1 - 0.051 14.1 1.0 0.12 12.9 0.1 2.1 2 0 0 2 2 2 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 EEQ36834.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Ras PF00071.22 EEQ36835.1 - 1.4e-26 93.0 0.2 1.6e-26 92.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ36835.1 - 1.4e-17 64.0 0.1 2e-17 63.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EEQ36835.1 - 5.1e-05 22.7 0.2 6.3e-05 22.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EEQ36835.1 - 0.00024 20.6 0.1 0.00028 20.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA PF00004.29 EEQ36837.1 - 4.8e-18 65.8 0.0 1.6e-17 64.2 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EEQ36837.1 - 2.5e-14 53.2 2.4 2.6e-14 53.1 0.1 2.3 2 0 0 2 2 2 1 AAA lid domain AAA_16 PF13191.6 EEQ36837.1 - 5.1e-09 36.7 0.0 2.3e-07 31.4 0.0 2.9 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.18 EEQ36837.1 - 1.4e-06 28.2 0.2 4e-06 26.7 0.0 1.9 2 0 0 2 2 1 1 BAH domain AAA_22 PF13401.6 EEQ36837.1 - 1.4e-05 25.4 0.0 3.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EEQ36837.1 - 0.00017 21.6 6.6 0.0011 19.0 0.0 4.2 3 2 1 4 4 4 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EEQ36837.1 - 0.00036 20.9 0.0 0.0015 18.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Merozoite_SPAM PF07133.11 EEQ36837.1 - 0.002 18.1 6.7 0.002 18.1 6.7 1.8 2 0 0 2 2 2 1 Merozoite surface protein (SPAM) Cdc6_C PF09079.11 EEQ36837.1 - 0.0033 17.3 0.7 0.14 12.2 0.1 2.9 2 0 0 2 2 2 1 CDC6, C terminal winged helix domain AAA_11 PF13086.6 EEQ36837.1 - 0.0048 16.7 6.3 0.1 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_32 PF13654.6 EEQ36837.1 - 0.023 13.5 7.1 1.3 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3381 PF11861.8 EEQ36837.1 - 0.037 13.8 10.5 0.13 12.1 10.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) AAA_24 PF13479.6 EEQ36837.1 - 0.043 13.5 0.1 14 5.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EEQ36837.1 - 0.064 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_assoc_2 PF16193.5 EEQ36837.1 - 0.081 13.3 0.1 0.67 10.3 0.1 2.6 2 0 0 2 2 2 0 AAA C-terminal domain UPF1_Zn_bind PF09416.10 EEQ36837.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) UvrD-helicase PF00580.21 EEQ36837.1 - 8.8 5.7 10.3 0.36 10.3 0.3 2.7 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain WGG PF10273.9 EEQ36838.1 - 4.7e-24 84.9 0.3 4.7e-24 84.9 0.3 1.9 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 Hid1 PF12722.7 EEQ36839.1 - 4.5e-258 858.6 2.0 5.5e-258 858.3 2.0 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EEQ36839.1 - 5.5e-26 91.2 0.0 4.4e-25 88.2 0.0 2.0 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Voldacs PF03517.13 EEQ36840.1 - 2.5e-13 50.4 0.2 1.7e-12 47.6 0.2 2.1 1 1 0 1 1 1 1 Regulator of volume decrease after cellular swelling Metallophos PF00149.28 EEQ36841.1 - 1.6e-35 123.5 0.0 3e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Orn_Arg_deC_N PF02784.16 EEQ36842.1 - 3.2e-75 252.7 0.0 4.2e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EEQ36842.1 - 2e-18 66.4 0.0 3e-18 65.8 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain VHS PF00790.19 EEQ36843.1 - 1.3e-27 96.3 0.0 2.4e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 VHS domain FYVE PF01363.21 EEQ36843.1 - 1.5e-17 63.4 4.8 3.9e-17 62.2 4.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 EEQ36843.1 - 5.2e-07 29.1 5.1 0.0024 17.7 2.1 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EEQ36843.1 - 0.038 14.2 2.1 0.088 13.0 2.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-AN1 PF01428.16 EEQ36843.1 - 0.23 11.7 5.8 0.44 10.8 5.8 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger zf-RING_2 PF13639.6 EEQ36843.1 - 0.55 10.6 5.2 1.1 9.6 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain Rot1 PF10681.9 EEQ36844.1 - 6.3e-97 323.1 0.4 7.3e-97 322.9 0.4 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Cyclin_N PF00134.23 EEQ36845.1 - 9.5e-33 112.6 0.1 1.8e-32 111.8 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain MatE PF01554.18 EEQ36846.1 - 2.1e-60 203.0 36.7 3.2e-37 127.7 10.5 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EEQ36846.1 - 1.1e-08 35.3 2.1 1.1e-08 35.3 2.1 3.9 3 1 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain ERG2_Sigma1R PF04622.12 EEQ36847.1 - 2.7e-86 288.2 0.1 3.2e-86 288.0 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PCI PF01399.27 EEQ36848.1 - 0.0052 17.3 0.1 0.016 15.7 0.1 1.8 1 0 0 1 1 1 1 PCI domain Aldo_ket_red PF00248.21 EEQ36849.1 - 2.3e-39 135.4 0.0 1.8e-38 132.5 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Whi5 PF08528.11 EEQ36850.1 - 0.037 13.6 5.6 0.037 13.6 5.6 2.1 2 0 0 2 2 2 0 Whi5 like Autophagy_N PF03986.13 EEQ36851.1 - 8.8e-45 152.0 0.4 1.5e-44 151.3 0.4 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EEQ36851.1 - 7.1e-16 57.4 1.0 7.1e-16 57.4 1.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EEQ36851.1 - 1.3e-13 51.3 0.0 2.7e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain LCAT PF02450.15 EEQ36852.1 - 1.6e-113 379.9 0.0 1.9e-113 379.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 EEQ36852.1 - 0.034 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ36852.1 - 0.16 11.2 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TRAF_BIRC3_bd PF16673.5 EEQ36853.1 - 0.04 13.7 2.6 0.04 13.7 2.6 2.1 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain RasGAP_C PF03836.15 EEQ36854.1 - 3.3e-40 137.4 8.9 3.3e-40 137.4 8.9 3.2 4 0 0 4 4 4 1 RasGAP C-terminus RasGAP PF00616.19 EEQ36854.1 - 9.8e-33 113.6 0.0 9.8e-33 113.6 0.0 2.8 4 0 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.27 EEQ36854.1 - 2.7e-08 32.9 16.3 0.055 13.3 0.0 9.0 10 0 0 10 10 10 3 IQ calmodulin-binding motif DUF1350 PF07082.11 EEQ36854.1 - 0.14 11.4 0.1 0.34 10.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) DHR10 PF18595.1 EEQ36854.1 - 7.9 6.6 14.1 3 7.9 0.2 3.2 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Spc24 PF08286.11 EEQ36854.1 - 9.1 6.6 9.0 1.7 8.9 1.4 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 CH PF00307.31 EEQ36855.1 - 1.3e-12 47.8 0.1 2.4e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Mis14 PF08641.12 EEQ36856.1 - 7.6e-25 87.8 4.4 7.6e-25 87.8 4.4 1.8 2 0 0 2 2 2 1 Kinetochore protein Mis14 like DUF5089 PF17002.5 EEQ36856.1 - 0.035 14.0 8.1 0.15 11.9 8.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5089) NPV_P10 PF05531.12 EEQ36856.1 - 0.082 13.4 3.8 4.6 7.8 3.7 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.11 EEQ36856.1 - 0.096 13.2 2.9 10 6.7 0.1 3.1 4 0 0 4 4 4 0 MerR, DNA binding DUF948 PF06103.11 EEQ36856.1 - 0.4 11.0 3.2 25 5.2 3.2 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Serine_rich PF08824.10 EEQ36856.1 - 0.5 10.4 4.2 9.1 6.3 0.5 2.5 1 1 1 2 2 2 0 Serine rich protein interaction domain P4Ha_N PF08336.11 EEQ36856.1 - 0.5 10.4 5.9 0.29 11.2 1.5 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Syntaxin-6_N PF09177.11 EEQ36856.1 - 0.7 10.5 8.0 7.3 7.2 5.1 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal HIP1_clath_bdg PF16515.5 EEQ36856.1 - 1.3 9.7 11.5 1.5 9.5 3.3 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ATP-synt_C PF00137.21 EEQ36857.1 - 1.7e-29 101.9 28.3 3.8e-19 68.8 9.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.8 EEQ36857.1 - 4.1 7.2 6.6 6.8 6.5 0.3 2.4 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain TIP49 PF06068.13 EEQ36858.1 - 3.3e-145 483.7 2.7 4.2e-145 483.4 2.7 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EEQ36858.1 - 9.9e-23 80.1 1.3 3.1e-22 78.5 1.1 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 EEQ36858.1 - 6e-08 33.2 2.2 7.7e-05 23.1 0.1 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ36858.1 - 2.9e-06 27.1 0.7 0.019 14.7 0.1 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ36858.1 - 0.00011 22.6 0.2 0.00048 20.5 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ36858.1 - 0.00039 20.7 0.1 0.066 13.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain DnaB_C PF03796.15 EEQ36858.1 - 0.00057 19.3 0.2 0.00057 19.3 0.2 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 EEQ36858.1 - 0.00089 19.6 0.3 0.0059 16.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EEQ36858.1 - 0.0085 15.5 0.5 0.18 11.1 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ36858.1 - 0.0087 16.1 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EEQ36858.1 - 0.018 15.3 0.0 0.06 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EEQ36858.1 - 0.021 14.5 0.0 8.8 6.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 EEQ36858.1 - 0.029 13.9 0.2 0.069 12.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain YopX PF09643.10 EEQ36858.1 - 0.071 13.2 0.2 0.19 11.8 0.2 1.8 1 0 0 1 1 1 0 YopX protein Cas9_b_hairpin PF17893.1 EEQ36858.1 - 0.088 12.6 0.0 4.6 7.1 0.0 2.7 3 0 0 3 3 3 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain AAA_7 PF12775.7 EEQ36858.1 - 0.094 12.2 0.2 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AMP-binding PF00501.28 EEQ36859.1 - 1.2e-71 241.5 0.0 5.3e-70 236.1 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme TPP_enzyme_N PF02776.18 EEQ36860.1 - 3.7e-22 78.7 0.0 6.8e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EEQ36860.1 - 3.5e-15 56.1 0.0 1.5e-14 54.0 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ36860.1 - 1.7e-06 27.8 0.0 5.5e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain PFK PF00365.20 EEQ36861.1 - 7.5e-185 612.8 5.6 9.6e-104 346.7 2.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 EEQ36861.1 - 0.034 13.8 0.1 0.13 11.9 0.1 2.0 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain SHOCT PF09851.9 EEQ36861.1 - 2.4 8.0 4.0 2 8.3 1.6 2.1 2 0 0 2 2 2 0 Short C-terminal domain Porin_3 PF01459.22 EEQ36862.1 - 3.7e-44 151.2 0.8 4.6e-44 150.9 0.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Porin_3 PF01459.22 EEQ36863.1 - 1.1e-35 123.5 0.0 1.4e-35 123.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic porin Inp1 PF12634.7 EEQ36864.1 - 2e-15 57.0 0.0 2e-15 57.0 0.0 2.4 2 1 0 2 2 2 1 Inheritance of peroxisomes protein 1 Rhomboid PF01694.22 EEQ36865.1 - 1.2e-12 48.1 11.3 2e-12 47.4 11.3 1.3 1 0 0 1 1 1 1 Rhomboid family DUF2484 PF10658.9 EEQ36865.1 - 3.2 8.1 6.3 0.52 10.6 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2484) Med9 PF07544.13 EEQ36866.1 - 9.7e-20 70.5 0.0 1.3e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 GvpG PF05120.12 EEQ36866.1 - 0.044 13.8 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Gas vesicle protein G Sipho_Gp157 PF05565.11 EEQ36866.1 - 0.044 13.8 0.2 0.059 13.4 0.2 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Pkinase PF00069.25 EEQ36867.1 - 4e-39 134.6 0.0 5.3e-26 91.6 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36867.1 - 1.5e-15 57.2 0.0 6.6e-15 55.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ36867.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ36867.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Gln-synt_C PF00120.24 EEQ36868.1 - 0.11 11.5 0.1 0.14 11.1 0.1 1.1 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain eIF-5_eIF-2B PF01873.17 EEQ36870.1 - 1.6e-39 134.4 0.0 2.6e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 GET2 PF08690.10 EEQ36870.1 - 0.0016 18.2 1.9 0.0023 17.7 1.9 1.2 1 0 0 1 1 1 1 GET complex subunit GET2 IF2_N PF04760.15 EEQ36870.1 - 0.024 14.4 0.0 0.21 11.4 0.0 2.4 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region zf-HYPF PF07503.12 EEQ36870.1 - 0.071 12.9 0.1 17 5.3 0.0 2.6 2 0 0 2 2 2 0 HypF finger TF_Zn_Ribbon PF08271.12 EEQ36870.1 - 0.1 12.2 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF2752 PF10825.8 EEQ36870.1 - 0.13 12.3 0.1 0.25 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) zinc_ribbon_6 PF14599.6 EEQ36870.1 - 0.33 11.0 1.8 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon Ank_4 PF13637.6 EEQ36871.1 - 3e-18 65.9 0.4 1.5e-12 47.7 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ36871.1 - 9.7e-17 61.3 0.1 9.1e-16 58.2 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ36871.1 - 2.1e-14 53.4 1.5 1e-08 35.3 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EEQ36871.1 - 6.4e-13 48.5 0.3 2.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EEQ36871.1 - 2e-12 46.1 0.1 2.4e-06 27.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat RTP1_C1 PF10363.9 EEQ36873.1 - 1.2e-28 99.5 0.1 4.5e-27 94.5 0.0 2.6 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EEQ36873.1 - 3.1e-09 36.3 1.7 3.1e-09 36.3 1.7 3.6 5 0 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT PF02985.22 EEQ36873.1 - 0.00024 21.1 0.2 11 6.6 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EEQ36873.1 - 0.0022 18.0 0.1 0.021 14.9 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 SLAIN PF15301.6 EEQ36873.1 - 0.034 13.4 0.3 0.047 13.0 0.3 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family Sigma70_ner PF04546.13 EEQ36873.1 - 0.043 13.7 2.8 0.068 13.0 2.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Tn7_Tnp_TnsA_C PF08721.11 EEQ36873.1 - 0.063 13.9 0.2 3.5 8.3 0.1 2.5 1 1 1 2 2 2 0 TnsA endonuclease C terminal HSP90 PF00183.18 EEQ36874.1 - 1.7e-221 736.6 33.7 2.4e-221 736.2 33.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EEQ36874.1 - 1.1e-14 54.9 0.0 2.5e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EEQ36874.1 - 5.2e-10 39.3 0.0 1.7e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 EEQ36874.1 - 0.26 11.3 1.5 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 Haem-binding uptake, Tiki superfamily, ChaN XPA_C PF05181.12 EEQ36875.1 - 4e-21 74.7 0.3 7.3e-21 73.9 0.3 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EEQ36875.1 - 1.2e-07 31.7 0.4 1.2e-07 31.7 0.4 2.5 3 0 0 3 3 3 1 XPA protein N-terminal DUF3172 PF11371.8 EEQ36876.1 - 0.056 13.2 0.3 0.13 12.0 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3172) Spermine_synth PF01564.17 EEQ36877.1 - 5.6e-75 250.9 0.0 1e-74 250.1 0.0 1.4 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EEQ36877.1 - 1.6e-20 72.7 0.0 2.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EEQ36877.1 - 0.00061 20.5 0.0 0.0011 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ36877.1 - 0.0013 19.4 0.0 0.0022 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain 5_nucleotid PF05761.14 EEQ36877.1 - 0.01 14.8 0.0 0.71 8.7 0.0 2.1 2 0 0 2 2 2 0 5' nucleotidase family DUF43 PF01861.16 EEQ36877.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 EEQ36877.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aconitase PF00330.20 EEQ36879.1 - 4e-152 507.4 0.0 5e-152 507.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEQ36879.1 - 3.1e-45 153.7 0.1 6.2e-45 152.7 0.1 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ABC_membrane PF00664.23 EEQ36880.1 - 4.6e-53 180.6 16.6 1.3e-26 93.9 2.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ36880.1 - 2.4e-17 63.8 0.0 4.8e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EEQ36880.1 - 2.7e-05 23.7 0.1 0.12 11.8 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EEQ36880.1 - 0.017 15.2 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EEQ36880.1 - 0.022 14.8 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AAA_29 PF13555.6 EEQ36880.1 - 0.028 14.2 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.6 EEQ36880.1 - 0.24 11.0 0.1 0.24 11.0 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EEQ36881.1 - 3e-29 102.3 0.0 6e-29 101.3 0.0 1.5 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EEQ36881.1 - 2.4e-06 27.1 1.6 7.8e-05 22.2 1.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EEQ36881.1 - 0.0044 17.1 0.1 0.012 15.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EEQ36881.1 - 0.016 14.9 0.1 0.042 13.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ36881.1 - 0.024 15.0 0.1 0.034 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 EEQ36881.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EEQ36881.1 - 0.081 13.2 0.1 1.3 9.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain MPC PF03650.13 EEQ36882.1 - 9.9e-48 160.9 0.0 1.1e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ANAPC8 PF04049.13 EEQ36884.1 - 2.9e-24 85.7 7.8 3.2e-17 62.9 0.2 3.3 2 2 0 3 3 3 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 EEQ36884.1 - 1.6e-12 46.5 7.1 0.039 14.2 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ36884.1 - 1.3e-09 37.4 12.4 0.0038 17.0 0.0 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36884.1 - 5.1e-08 33.1 0.0 0.4 11.6 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ36884.1 - 2.1e-05 24.3 11.4 0.95 9.7 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ36884.1 - 0.0019 18.4 6.5 0.69 10.2 0.0 3.7 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EEQ36884.1 - 0.0045 17.3 3.8 1.1 9.6 0.0 4.3 4 2 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ36884.1 - 0.025 14.6 0.2 20 5.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2247 PF10004.9 EEQ36884.1 - 0.046 13.5 0.4 0.12 12.1 0.2 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) SRP68 PF16969.5 EEQ36884.1 - 0.05 12.6 0.1 0.068 12.2 0.1 1.1 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 TPR_6 PF13174.6 EEQ36884.1 - 0.054 14.2 1.2 87 4.1 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat FAD-SLDH PF12318.8 EEQ36884.1 - 0.28 11.2 1.1 1.2 9.2 0.8 2.0 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Aminotran_1_2 PF00155.21 EEQ36885.1 - 3e-39 135.2 0.0 6.9e-39 134.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II PHD20L1_u1 PF16660.5 EEQ36885.1 - 0.04 14.7 0.0 0.1 13.4 0.0 1.6 1 0 0 1 1 1 0 PHD finger protein 20-like protein 1 zf-C3HC4_3 PF13920.6 EEQ36886.1 - 9.9e-08 31.7 9.1 9.9e-08 31.7 9.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CpG_bind_C PF12269.8 EEQ36886.1 - 0.0053 16.6 0.3 0.01 15.7 0.3 1.4 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain FGAR-AT_N PF18076.1 EEQ36886.1 - 0.097 12.7 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase N-terminal PROCN PF08083.11 EEQ36887.1 - 1.2e-223 742.2 7.4 2e-223 741.5 7.4 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EEQ36887.1 - 6.9e-123 408.7 0.2 1.8e-122 407.3 0.2 1.8 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EEQ36887.1 - 2e-84 281.3 1.2 2e-84 281.3 1.2 2.1 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EEQ36887.1 - 1.6e-78 261.9 2.4 3.6e-78 260.8 2.4 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EEQ36887.1 - 6.7e-73 243.1 0.1 1.6e-72 241.9 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EEQ36887.1 - 6e-47 158.6 0.0 1.4e-46 157.4 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 EEQ36887.1 - 5.8e-44 148.4 0.1 1.6e-43 146.9 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 EEQ36887.1 - 0.00064 19.7 0.0 0.0023 17.9 0.0 2.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TPD PF14811.6 EEQ36887.1 - 0.19 11.6 0.8 0.92 9.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function TPD sequence-motif NPR3 PF03666.13 EEQ36888.1 - 1.8e-127 426.0 4.5 5.8e-112 374.9 1.2 3.2 3 1 1 4 4 4 2 Nitrogen Permease regulator of amino acid transport activity 3 ANAPC_CDC26 PF10471.9 EEQ36888.1 - 5.4 7.9 9.8 0.61 10.9 1.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 ECH_1 PF00378.20 EEQ36889.1 - 3e-22 79.2 0.0 3.6e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ36889.1 - 1.4e-10 41.2 0.0 1.7e-10 41.0 0.0 1.2 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Arf PF00025.21 EEQ36890.1 - 4.7e-80 267.1 0.0 5.3e-80 267.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEQ36890.1 - 1.6e-14 54.2 0.0 2.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EEQ36890.1 - 4e-14 52.4 0.0 5e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EEQ36890.1 - 3e-13 49.7 0.0 3.2e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEQ36890.1 - 2e-12 47.0 1.1 9.3e-09 34.9 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EEQ36890.1 - 1.5e-10 40.9 0.0 1.8e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ36890.1 - 3.5e-06 27.1 0.0 5.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EEQ36890.1 - 0.009 15.3 0.5 0.021 14.1 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase RhoGAP PF00620.27 EEQ36893.1 - 1.9e-13 50.5 0.3 4.9e-13 49.2 0.3 1.8 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 EEQ36893.1 - 1.3e-12 47.6 0.0 2.7e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EEQ36893.1 - 1.3e-08 35.0 0.2 4.2e-07 30.2 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain FMN_dh PF01070.18 EEQ36894.1 - 1.3e-110 369.7 0.1 1.9e-110 369.2 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EEQ36894.1 - 2.6e-22 78.7 0.0 4.7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EEQ36894.1 - 4e-08 32.8 0.1 6.1e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EEQ36894.1 - 5.5e-05 22.3 0.3 0.00019 20.6 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EEQ36894.1 - 0.00016 21.2 0.2 0.00028 20.4 0.2 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Peptidase_M19 PF01244.21 EEQ36894.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) His_biosynth PF00977.21 EEQ36894.1 - 0.11 11.9 1.0 3.5 7.0 0.0 2.7 3 0 0 3 3 3 0 Histidine biosynthesis protein Collagen PF01391.18 EEQ36895.1 - 1.2e-35 121.0 388.6 4.2e-09 36.0 37.5 12.3 2 1 8 11 11 11 8 Collagen triple helix repeat (20 copies) Flo11 PF10182.9 EEQ36895.1 - 1.7e-05 25.0 0.1 2.6e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Flo11 domain Zn_clus PF00172.18 EEQ36896.1 - 7.9e-09 35.5 8.1 1.5e-08 34.6 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ36896.1 - 7.7e-05 21.9 0.2 0.00032 19.8 0.2 2.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 EEQ36897.1 - 1.1e-118 397.0 19.8 1.3e-118 396.8 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ36897.1 - 2.3e-19 69.5 34.2 1.4e-14 53.8 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.7 EEQ36897.1 - 0.04 13.9 2.7 0.84 9.7 0.6 3.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C HlyIII PF03006.20 EEQ36898.1 - 1.2e-25 90.6 14.2 1.6e-25 90.1 14.2 1.2 1 0 0 1 1 1 1 Haemolysin-III related LicD PF04991.13 EEQ36899.1 - 3.1e-22 79.8 5.8 3.5e-21 76.4 0.8 4.1 3 2 2 5 5 5 2 LicD family DUF3818 PF12825.7 EEQ36900.1 - 9.9e-06 24.8 0.3 1.9e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) DUF3818 PF12825.7 EEQ36901.1 - 3.7e-56 190.6 1.4 3.7e-56 190.6 1.4 1.6 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EEQ36902.1 - 8.6e-32 109.9 2.4 1.4e-31 109.2 2.4 1.3 1 0 0 1 1 1 1 PX-associated DUF1831 PF08866.10 EEQ36902.1 - 0.05 14.1 0.1 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Putative amino acid metabolism NGP1NT PF08153.12 EEQ36903.1 - 6.1e-49 165.5 0.2 9.5e-49 164.9 0.2 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EEQ36903.1 - 0.028 14.5 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Glyco_hydro_125 PF06824.11 EEQ36903.1 - 0.032 13.1 0.1 0.044 12.7 0.1 1.1 1 0 0 1 1 1 0 Metal-independent alpha-mannosidase (GH125) DUF1027 PF06265.11 EEQ36903.1 - 0.14 12.1 0.7 18 5.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) CAF1 PF04857.20 EEQ36905.1 - 5.1e-06 25.9 10.1 0.0052 16.0 0.0 3.2 2 1 0 3 3 3 2 CAF1 family ribonuclease Ndc1_Nup PF09531.10 EEQ36905.1 - 2 7.0 14.5 2.9 6.5 14.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC50 PF03381.15 EEQ36906.1 - 4.7e-93 311.7 0.9 5.7e-93 311.5 0.9 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mito_carr PF00153.27 EEQ36907.1 - 4.8e-21 74.5 1.4 2.9e-16 59.2 0.4 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ36907.1 - 0.17 11.0 1.3 0.28 10.3 0.3 1.7 2 0 0 2 2 2 0 Gammaproteobacterial serine protease MEIOC PF15189.6 EEQ36908.1 - 0.014 15.0 0.0 0.041 13.5 0.0 1.7 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC GPS2_interact PF15784.5 EEQ36909.1 - 8.8e-05 22.9 0.7 0.00043 20.6 0.7 2.2 1 0 0 1 1 1 1 G-protein pathway suppressor 2-interacting domain MIP PF00230.20 EEQ36911.1 - 7.4e-24 84.7 12.6 9e-24 84.4 12.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein RNA_pol_Rpc82 PF05645.13 EEQ36912.1 - 1.9e-55 188.4 0.1 3.5e-55 187.6 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EEQ36912.1 - 7.3e-24 83.6 4.3 7.7e-19 67.6 0.5 3.6 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EEQ36912.1 - 1.4e-06 28.1 4.9 0.018 14.9 0.1 3.4 2 1 1 3 3 3 2 TFIIE alpha subunit RecG_wedge PF17191.4 EEQ36912.1 - 0.0051 16.5 0.5 0.52 9.9 0.0 2.9 3 0 0 3 3 3 1 RecG wedge domain TPR_2 PF07719.17 EEQ36913.1 - 9.5e-31 103.4 18.7 0.002 18.1 0.0 13.8 14 0 0 14 14 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ36913.1 - 4.5e-27 94.4 13.2 1.8e-06 28.4 0.3 10.3 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ36913.1 - 8.7e-26 88.6 20.8 0.00074 19.2 0.0 13.9 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ36913.1 - 4.8e-23 81.5 5.4 0.0012 19.4 0.0 9.6 6 3 2 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36913.1 - 1.7e-21 75.1 17.5 0.007 17.1 0.4 13.0 12 4 4 16 16 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ36913.1 - 1.8e-21 74.5 23.5 0.0072 16.5 0.0 13.1 13 1 0 13 13 13 6 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ36913.1 - 4.4e-20 71.7 10.5 0.037 14.3 0.0 10.3 9 3 1 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ36913.1 - 6e-16 57.8 4.9 0.00058 19.5 0.0 10.2 7 2 3 10 10 10 3 TPR repeat TPR_22 PF18833.1 EEQ36913.1 - 1.4e-13 50.8 0.1 4.9e-13 49.0 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ36913.1 - 4.6e-13 48.6 14.6 0.22 12.0 0.1 11.4 13 0 0 13 13 11 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ36913.1 - 1e-12 47.8 6.4 0.76 10.6 0.0 10.7 10 0 0 10 10 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ36913.1 - 2.9e-12 46.7 6.5 0.00011 22.3 0.0 6.9 5 3 3 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EEQ36913.1 - 2.6e-11 43.5 6.1 0.8 9.9 0.0 9.1 9 2 2 11 11 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ36913.1 - 2.5e-06 27.1 1.1 14 6.0 0.0 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEQ36913.1 - 0.00035 20.6 0.6 0.15 12.1 0.0 5.2 7 0 0 7 7 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EEQ36913.1 - 0.0061 16.4 0.1 55 3.8 0.0 6.0 8 0 0 8 8 7 0 Tetratricopeptide repeat RPN7 PF10602.9 EEQ36913.1 - 0.0097 15.6 12.1 3.6 7.3 1.4 5.2 5 1 0 5 5 5 2 26S proteasome subunit RPN7 PSD4 PF07631.11 EEQ36913.1 - 0.038 14.5 0.6 0.5 10.9 0.3 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF1592) HrpB1_HrpK PF09613.10 EEQ36913.1 - 0.043 13.5 0.0 2.3 7.9 0.0 3.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_4 PF07721.14 EEQ36913.1 - 0.066 13.9 0.9 1.1e+02 3.9 0.0 5.3 7 0 0 7 7 2 0 Tetratricopeptide repeat DUF1974 PF09317.11 EEQ36913.1 - 0.073 12.6 4.5 8.9 5.8 0.5 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1974) PPR PF01535.20 EEQ36913.1 - 0.12 12.6 2.8 20 5.7 0.1 4.7 6 0 0 6 6 4 0 PPR repeat Sel1 PF08238.12 EEQ36913.1 - 0.81 10.5 2.8 13 6.7 0.1 4.1 3 0 0 3 3 3 0 Sel1 repeat ATG13 PF10033.9 EEQ36914.1 - 2.6e-66 223.7 1.2 4.3e-66 223.0 1.2 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 AFG1_ATPase PF03969.16 EEQ36915.1 - 1.7e-73 247.6 0.0 2e-70 237.5 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EEQ36915.1 - 9e-05 22.9 0.1 0.5 10.7 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 EEQ36915.1 - 0.013 15.5 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EEQ36915.1 - 0.03 14.6 0.0 0.074 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ36915.1 - 0.12 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain TsaE PF02367.17 EEQ36915.1 - 0.16 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SANT_DAMP1_like PF16282.5 EEQ36916.1 - 4.7e-16 58.7 3.8 4.6e-15 55.6 0.5 2.5 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_6 PF13921.6 EEQ36916.1 - 3.9e-05 23.8 0.2 0.00017 21.8 0.2 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EEQ36916.1 - 0.0019 18.3 0.0 0.006 16.8 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mus7 PF09462.10 EEQ36917.1 - 8e-29 101.0 21.8 9.9e-25 87.5 3.4 2.5 2 0 0 2 2 2 2 Mus7/MMS22 family 3Beta_HSD PF01073.19 EEQ36919.1 - 1.9e-84 283.0 0.0 2.4e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EEQ36919.1 - 3e-29 102.2 0.0 4e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEQ36919.1 - 2.7e-19 69.7 0.0 7.1e-19 68.4 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEQ36919.1 - 7.8e-16 58.0 0.0 6.8e-15 54.9 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EEQ36919.1 - 2.2e-11 43.4 0.0 3.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EEQ36919.1 - 2.3e-10 40.7 0.0 4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EEQ36919.1 - 9.2e-07 28.3 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EEQ36919.1 - 0.00063 19.7 0.0 0.0071 16.3 0.0 2.5 2 1 0 2 2 2 1 KR domain Methyltransf_2 PF00891.18 EEQ36919.1 - 0.046 13.0 0.0 0.15 11.3 0.0 1.9 3 0 0 3 3 3 0 O-methyltransferase domain Glyco_hydro_72 PF03198.14 EEQ36920.1 - 8.6e-64 215.8 6.6 1.2e-63 215.3 6.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EEQ36920.1 - 3.2e-26 91.8 4.7 8.2e-26 90.5 4.7 1.8 1 0 0 1 1 1 1 X8 domain G-patch PF01585.23 EEQ36922.1 - 1.2e-12 47.5 0.1 2.9e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEQ36922.1 - 1.8e-05 24.7 0.1 1.8e-05 24.7 0.1 4.3 2 1 0 2 2 1 1 G-patch domain RR_TM4-6 PF06459.12 EEQ36922.1 - 0.00078 19.4 33.1 0.0012 18.8 33.1 1.4 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 EEQ36922.1 - 0.06 12.8 10.8 0.08 12.4 10.8 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SAPS PF04499.15 EEQ36922.1 - 0.15 10.8 16.6 0.21 10.3 16.6 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 EEQ36922.1 - 0.18 11.8 18.6 0.24 11.4 18.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF262 PF03235.14 EEQ36922.1 - 0.79 9.8 14.8 1.3 9.2 14.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF262 SLC12 PF03522.15 EEQ36922.1 - 0.86 8.5 28.4 1.2 8.1 28.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Sec62 PF03839.16 EEQ36922.1 - 1.6 8.2 36.7 2.8 7.4 36.7 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 EEQ36922.1 - 2.3 6.9 31.8 3.2 6.5 31.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 EEQ36922.1 - 2.5 5.1 15.9 2.6 5.1 15.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DDRGK PF09756.9 EEQ36922.1 - 2.5 7.6 52.9 4.7 6.8 52.9 1.5 1 0 0 1 1 1 0 DDRGK domain Presenilin PF01080.17 EEQ36922.1 - 2.9 6.6 27.7 3.8 6.2 27.7 1.1 1 0 0 1 1 1 0 Presenilin MCM_bind PF09739.9 EEQ36922.1 - 5.3 5.4 25.4 8.3 4.7 25.4 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF4407 PF14362.6 EEQ36922.1 - 6.2 6.1 18.9 7.6 5.8 18.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5427 PF10310.9 EEQ36922.1 - 6.5 5.6 32.5 9.6 5.0 32.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2828 PF11443.8 EEQ36922.1 - 7.2 4.6 28.4 12 3.9 28.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SID-1_RNA_chan PF13965.6 EEQ36922.1 - 8.3 4.7 11.4 9.6 4.5 11.4 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 B-block_TFIIIC PF04182.12 EEQ36923.1 - 2.5e-13 50.0 0.2 2.3e-12 46.9 0.0 2.7 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC HTH_20 PF12840.7 EEQ36923.1 - 0.0017 18.4 0.0 5 7.3 0.1 3.5 4 0 0 4 4 4 2 Helix-turn-helix domain MarR_2 PF12802.7 EEQ36923.1 - 0.0056 16.6 0.1 0.47 10.4 0.0 3.3 3 0 0 3 3 3 1 MarR family HTH_24 PF13412.6 EEQ36923.1 - 0.063 12.8 0.1 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_12 PF08461.10 EEQ36923.1 - 0.079 12.9 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease R winged-helix domain N6-adenineMlase PF10237.9 EEQ36924.1 - 1.6e-54 184.1 0.1 2.3e-54 183.5 0.1 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase EF1_GNE PF00736.19 EEQ36925.1 - 8.1e-32 109.3 1.1 8.1e-32 109.3 1.1 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EEQ36925.1 - 1.3e-13 51.1 6.5 1.3e-13 51.1 6.5 3.0 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 EEQ36925.1 - 0.047 13.7 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF5355 PF17306.2 EEQ36926.1 - 1.9e-98 329.6 4.8 4.8e-98 328.2 1.4 2.0 2 0 0 2 2 2 2 Family of unknown function (DUF5355) YiaAB PF05360.14 EEQ36926.1 - 0.17 12.2 0.3 0.44 10.8 0.3 1.6 1 0 0 1 1 1 0 yiaA/B two helix domain MATH PF00917.26 EEQ36926.1 - 0.3 11.3 2.6 0.5 10.5 0.8 2.2 2 0 0 2 2 2 0 MATH domain GDA1_CD39 PF01150.17 EEQ36927.1 - 3.1e-126 421.5 0.5 4.6e-126 420.9 0.5 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Plasmodium_Vir PF05795.11 EEQ36927.1 - 0.0023 17.4 0.2 0.0082 15.6 0.0 1.9 2 0 0 2 2 2 1 Plasmodium vivax Vir protein GN3L_Grn1 PF08701.11 EEQ36928.1 - 1.2e-23 83.0 16.6 2.8e-23 81.8 16.6 1.7 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EEQ36928.1 - 2e-19 69.8 0.8 3.7e-15 56.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ36928.1 - 2e-11 43.6 0.5 8.6e-10 38.4 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EEQ36928.1 - 1.4e-05 24.7 0.1 0.013 15.1 0.0 3.1 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ36928.1 - 5.3e-05 23.2 0.8 0.00075 19.4 0.8 2.2 1 1 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EEQ36928.1 - 0.00016 21.8 7.0 0.44 10.6 2.5 3.7 2 2 0 3 3 3 2 Dynamin family Roc PF08477.13 EEQ36928.1 - 0.00028 21.1 0.1 0.64 10.3 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 EEQ36928.1 - 0.0084 15.1 0.8 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 EEQ36928.1 - 0.013 14.8 0.3 0.073 12.4 0.1 2.1 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 EEQ36928.1 - 0.014 14.9 0.4 0.96 9.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EEQ36928.1 - 0.031 14.8 2.2 0.12 12.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Ras PF00071.22 EEQ36928.1 - 0.056 13.1 0.1 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Ras family TniB PF05621.11 EEQ36928.1 - 0.056 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EEQ36928.1 - 0.84 10.0 0.0 0.84 10.0 0.0 2.7 2 2 0 2 2 2 0 AAA ATPase domain UPF0767 PF15990.5 EEQ36928.1 - 1.6 8.9 7.1 1.9 8.7 0.0 3.4 2 1 1 3 3 3 0 UPF0767 family CAP_GLY PF01302.25 EEQ36929.1 - 1.1e-12 47.7 0.2 1.9e-12 47.0 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EEQ36929.1 - 1.1e-10 41.6 18.1 0.0029 18.0 0.1 5.1 4 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEQ36929.1 - 2.4e-05 24.0 19.6 0.0066 16.2 2.0 4.8 1 1 3 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EEQ36929.1 - 0.00047 19.7 4.6 0.0024 17.4 0.4 2.4 1 1 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 EEQ36929.1 - 0.0029 17.9 16.7 7.6 7.5 0.9 7.0 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 EEQ36929.1 - 0.081 13.0 17.2 11 6.4 0.0 6.8 6 0 0 6 6 6 0 Leucine Rich repeat Pre-PUA PF17832.1 EEQ36930.1 - 3.3e-21 75.8 0.1 5.5e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EEQ36930.1 - 1e-19 70.3 0.0 1.7e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 EEQ36930.1 - 0.025 14.9 0.2 0.051 13.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) ResIII PF04851.15 EEQ36931.1 - 2.7e-20 73.1 3.6 3.3e-20 72.8 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ36931.1 - 2.1e-19 70.0 0.0 2.1e-18 66.7 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ36931.1 - 1e-18 67.7 2.2 3.5e-17 62.7 1.0 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EEQ36931.1 - 0.00016 21.4 0.2 0.00045 20.0 0.0 1.8 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EEQ36931.1 - 0.0026 18.0 0.0 0.012 15.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF1752 PF08550.10 EEQ36932.1 - 0.02 14.7 0.2 0.068 13.0 0.2 1.9 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) DNA_ligase_A_M PF01068.21 EEQ36933.1 - 1.2e-45 155.7 0.1 2.2e-45 154.8 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EEQ36933.1 - 9.4e-25 87.9 0.1 1.6e-24 87.2 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.26 EEQ36933.1 - 6.3e-16 58.5 0.0 4.2e-09 36.7 0.0 2.7 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EEQ36933.1 - 6.4e-15 55.3 0.1 4.2e-07 30.3 0.0 2.8 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 EEQ36933.1 - 3.6e-08 33.9 0.1 9.9e-08 32.5 0.1 1.8 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 EEQ36933.1 - 4.4e-08 33.6 0.0 1.1e-07 32.3 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 EEQ36933.1 - 1e-05 25.5 0.6 0.036 13.9 0.0 2.6 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain Endotoxin_N PF03945.14 EEQ36933.1 - 0.12 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Aa_trans PF01490.18 EEQ36934.1 - 5.4e-80 269.1 37.1 6.2e-80 268.9 37.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 EEQ36934.1 - 0.0013 17.6 37.9 0.0024 16.8 37.9 1.4 1 1 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.18 EEQ36935.1 - 5.6e-31 107.6 6.4 1e-30 106.7 6.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ36935.1 - 2.5e-09 37.1 8.6 4.5e-09 36.3 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCD1 PF09798.9 EEQ36935.1 - 0.004 15.8 0.0 0.007 14.9 0.0 1.3 1 0 0 1 1 1 1 DNA damage checkpoint protein Dysbindin PF04440.16 EEQ36935.1 - 0.0044 17.2 0.7 2.7 8.1 0.2 2.5 2 0 0 2 2 2 2 Dysbindin (Dystrobrevin binding protein 1) TPP_enzyme_N PF02776.18 EEQ36936.1 - 1.7e-25 89.6 0.0 2.8e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ36936.1 - 3.8e-22 78.5 0.0 5.6e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF362 PF04015.12 EEQ36936.1 - 0.00032 21.0 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF362) Viral_DNA_Zn_bi PF03728.13 EEQ36936.1 - 0.0053 17.3 0.1 0.024 15.2 0.2 2.0 1 1 0 2 2 2 1 Viral DNA-binding protein, zinc binding domain CO_dh PF02552.16 EEQ36936.1 - 0.03 14.1 0.1 0.051 13.3 0.1 1.3 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Alg6_Alg8 PF03155.15 EEQ36937.1 - 3.3e-167 557.3 37.5 3.8e-167 557.1 37.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Fis1_TPR_C PF14853.6 EEQ36938.1 - 7.5e-24 83.6 0.9 1.3e-23 82.8 0.3 1.7 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EEQ36938.1 - 2.3e-10 40.0 0.1 4.4e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EEQ36938.1 - 0.0022 18.0 0.8 0.0074 16.3 0.4 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ36938.1 - 0.0054 17.3 1.9 0.046 14.4 0.2 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ36938.1 - 0.079 13.8 0.6 0.31 12.0 0.1 2.3 1 1 2 3 3 3 0 Tetratricopeptide repeat A_deamin PF02137.18 EEQ36939.1 - 7.4e-34 117.7 0.0 1.6e-33 116.5 0.0 1.5 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain Ank_2 PF12796.7 EEQ36940.1 - 8.4e-08 32.7 0.1 1.9e-07 31.6 0.0 1.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ36940.1 - 2e-07 30.8 0.0 0.084 13.5 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EEQ36940.1 - 4e-07 30.2 0.0 0.0043 17.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EEQ36940.1 - 8e-06 26.0 0.0 0.023 15.0 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ36940.1 - 0.00034 21.1 0.2 0.037 14.6 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) XPC-binding PF09280.11 EEQ36940.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 XPC-binding domain ECH_2 PF16113.5 EEQ36940.1 - 0.14 11.6 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Ribul_P_3_epim PF00834.19 EEQ36941.1 - 2.4e-66 222.9 0.0 2.8e-66 222.7 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 EEQ36941.1 - 0.1 11.9 0.2 0.14 11.4 0.2 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 EEQ36941.1 - 0.18 11.2 0.0 0.59 9.6 0.0 1.8 3 0 0 3 3 3 0 Histidine biosynthesis protein Alb1 PF09135.11 EEQ36942.1 - 3.2e-05 24.8 5.9 5.7e-05 23.9 5.9 1.4 1 0 0 1 1 1 1 Alb1 Apt1 PF10351.9 EEQ36943.1 - 1.7 7.4 15.8 2.4 6.9 15.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EEQ36943.1 - 3.3 6.1 14.2 3.9 5.9 14.2 1.0 1 0 0 1 1 1 0 Macoilin family CobT PF06213.12 EEQ36943.1 - 6.8 6.0 7.5 8.2 5.7 7.5 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Dehydrin PF00257.19 EEQ36943.1 - 9.8 6.7 20.8 14 6.2 20.8 1.2 1 0 0 1 1 1 0 Dehydrin DUF775 PF05603.12 EEQ36944.1 - 9.8e-64 214.6 0.4 1.1e-63 214.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) RCC1 PF00415.18 EEQ36945.1 - 2.6e-28 98.4 13.6 5.8e-06 26.8 0.0 6.9 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEQ36945.1 - 2e-20 72.1 21.9 6.2e-08 32.2 0.0 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat SNF2_N PF00176.23 EEQ36946.1 - 4.8e-57 193.3 0.4 7.6e-57 192.6 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ36946.1 - 6.7e-19 68.3 0.0 6.1e-17 62.0 0.1 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ36946.1 - 6.9e-12 45.7 0.1 3.2e-11 43.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEQ36946.1 - 0.006 15.8 0.4 0.019 14.2 0.2 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase HIGH_NTase1_ass PF16581.5 EEQ36946.1 - 0.11 12.5 2.4 0.16 12.0 0.1 2.4 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region Nfu_N PF08712.11 EEQ36947.1 - 1.4e-30 105.2 0.1 2.7e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EEQ36947.1 - 4.7e-28 97.1 0.0 7.2e-28 96.5 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain RRM_1 PF00076.22 EEQ36948.1 - 0.0022 17.8 1.5 5.7 6.8 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) POC3_POC4 PF10448.9 EEQ36949.1 - 7.9e-07 29.2 0.1 9.9e-07 28.9 0.1 1.1 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 Nop53 PF07767.11 EEQ36950.1 - 7.4e-63 213.3 28.4 9e-63 213.0 28.4 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) YvrJ PF12841.7 EEQ36950.1 - 0.08 12.5 1.2 0.21 11.1 1.2 1.8 1 0 0 1 1 1 0 YvrJ protein family Pkinase PF00069.25 EEQ36951.1 - 2.3e-69 233.7 0.0 2.8e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ36951.1 - 4.1e-38 131.1 0.0 5.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ36951.1 - 1.9e-06 27.4 0.0 3.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ36951.1 - 0.0004 19.3 0.0 0.00064 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EEQ36951.1 - 0.00072 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EEQ36951.1 - 0.0035 16.7 0.0 0.0052 16.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ36951.1 - 0.0039 17.1 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EEQ36951.1 - 0.0068 16.1 0.0 0.055 13.1 0.0 2.0 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EEQ36951.1 - 0.038 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EEQ36951.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family RFC1 PF08519.12 EEQ36952.1 - 1e-56 191.4 0.7 3.1e-56 189.9 0.1 2.1 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EEQ36952.1 - 1.8e-13 50.7 0.0 5.7e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EEQ36952.1 - 3.8e-11 43.5 0.1 2.1e-10 41.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEQ36952.1 - 1.9e-07 31.2 0.6 4.7e-07 29.9 0.1 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EEQ36952.1 - 0.00031 20.5 0.0 0.00065 19.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ36952.1 - 0.00099 19.5 0.7 0.012 16.0 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain DNA_pol3_delta PF06144.13 EEQ36952.1 - 0.0018 18.1 0.1 0.0092 15.8 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.6 EEQ36952.1 - 0.012 15.9 0.0 0.047 14.0 0.0 2.1 1 0 0 1 1 1 0 AAA domain PTCB-BRCT PF12738.7 EEQ36952.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain RNA_helicase PF00910.22 EEQ36952.1 - 0.022 15.1 0.0 0.11 12.9 0.0 2.3 1 1 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EEQ36952.1 - 0.041 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EEQ36952.1 - 0.052 13.7 0.6 0.18 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_assoc_2 PF16193.5 EEQ36952.1 - 0.11 12.8 0.0 0.4 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_18 PF13238.6 EEQ36952.1 - 0.27 11.8 0.0 0.27 11.8 0.0 2.3 2 0 0 2 2 1 0 AAA domain YL1 PF05764.13 EEQ36952.1 - 0.42 10.7 36.3 1.9 8.5 1.4 3.4 3 0 0 3 3 3 0 YL1 nuclear protein GRAB PF10375.9 EEQ36953.1 - 6.8e-07 28.9 2.6 1.8e-06 27.6 2.6 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.9 EEQ36953.1 - 2.1e-05 24.6 55.3 0.00041 20.4 28.6 5.1 1 1 4 5 5 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 EEQ36953.1 - 0.00013 20.9 87.1 0.019 13.9 34.0 4.1 1 1 3 4 4 4 3 Spc7 kinetochore protein GAS PF13851.6 EEQ36953.1 - 0.00083 18.8 38.1 0.00083 18.8 38.1 4.3 1 1 3 4 4 4 2 Growth-arrest specific micro-tubule binding Filament PF00038.21 EEQ36953.1 - 0.0009 18.9 72.3 0.0012 18.5 46.8 2.8 1 1 2 3 3 3 2 Intermediate filament protein DivIC PF04977.15 EEQ36953.1 - 0.0028 17.4 1.3 0.0028 17.4 1.3 8.5 1 1 7 8 8 8 2 Septum formation initiator Yuri_gagarin PF15934.5 EEQ36953.1 - 0.0034 17.3 21.2 0.0034 17.3 21.2 3.0 1 1 2 3 3 1 1 Yuri gagarin ADIP PF11559.8 EEQ36953.1 - 0.0065 16.6 19.3 0.0065 16.6 19.3 6.1 1 1 5 6 6 6 3 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EEQ36953.1 - 0.0069 16.9 21.8 0.0069 16.9 21.8 4.9 1 1 4 5 5 4 2 Apg6 coiled-coil region Lebercilin PF15619.6 EEQ36953.1 - 0.0091 15.7 34.8 0.0091 15.7 34.8 4.2 2 1 2 4 4 2 2 Ciliary protein causing Leber congenital amaurosis disease TMF_TATA_bd PF12325.8 EEQ36953.1 - 0.013 15.7 79.5 0.14 12.4 8.7 6.2 1 1 5 6 6 6 0 TATA element modulatory factor 1 TATA binding HALZ PF02183.18 EEQ36953.1 - 0.017 15.4 0.6 0.017 15.4 0.6 7.0 6 1 2 8 8 7 0 Homeobox associated leucine zipper TSC22 PF01166.18 EEQ36953.1 - 0.017 15.4 2.1 0.017 15.4 2.1 8.4 3 3 7 10 10 10 0 TSC-22/dip/bun family DUF3450 PF11932.8 EEQ36953.1 - 0.021 14.1 65.5 0.028 13.7 8.5 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF3450) DUF3772 PF12607.8 EEQ36953.1 - 0.28 11.0 2.7 0.2 11.4 0.3 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3772) DUF4407 PF14362.6 EEQ36953.1 - 0.34 10.2 56.1 2.1 7.6 22.9 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Golgin_A5 PF09787.9 EEQ36953.1 - 0.43 10.0 83.4 0.036 13.5 24.7 4.3 1 1 3 4 4 4 0 Golgin subfamily A member 5 THP2 PF09432.10 EEQ36953.1 - 1.7 8.7 30.1 0.25 11.4 13.0 3.7 1 1 2 3 3 3 0 Tho complex subunit THP2 AAA_13 PF13166.6 EEQ36953.1 - 2 6.9 66.0 0.36 9.4 33.3 2.1 1 1 1 2 2 2 0 AAA domain TLE_N PF03920.15 EEQ36953.1 - 2.8 8.0 29.3 0.24 11.5 0.9 4.1 3 1 1 4 4 3 0 Groucho/TLE N-terminal Q-rich domain WXG100 PF06013.12 EEQ36953.1 - 4.3 7.6 20.5 0.028 14.6 4.6 4.6 4 1 0 4 4 4 0 Proteins of 100 residues with WXG DUF3584 PF12128.8 EEQ36953.1 - 6.5 4.1 73.1 4 4.8 44.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) KASH_CCD PF14662.6 EEQ36953.1 - 7.1 6.4 87.6 0.022 14.6 18.5 3.8 1 1 3 4 4 3 0 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 EEQ36953.1 - 7.4 6.3 73.7 0.72 9.6 9.3 4.8 1 1 4 5 5 5 0 Domain of unknown function (DUF4201) Oxysterol_BP PF01237.18 EEQ36955.1 - 9.5e-66 222.1 1.1 1.5e-63 214.9 1.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein GWT1 PF06423.12 EEQ36956.1 - 9.9e-37 126.4 6.9 9.9e-37 126.4 6.9 3.0 3 1 0 3 3 3 1 GWT1 Spo7 PF03907.13 EEQ36957.1 - 5.4e-64 215.7 1.6 9.5e-64 214.9 1.6 1.4 1 0 0 1 1 1 1 Spo7-like protein FAD_binding_2 PF00890.24 EEQ36958.1 - 1.6e-77 261.4 0.0 1.8e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EEQ36958.1 - 4.7e-12 46.2 0.3 5.8e-11 42.6 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EEQ36958.1 - 9.6e-10 38.4 0.7 4.9e-09 36.0 0.7 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ36958.1 - 1.6e-09 37.9 1.5 2.6e-08 34.0 0.1 2.7 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EEQ36958.1 - 4.7e-09 35.4 0.3 0.00032 19.5 0.3 2.3 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.14 EEQ36958.1 - 2.3e-08 33.7 1.8 3e-07 30.0 0.6 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ36958.1 - 8.6e-07 28.4 3.5 0.00026 20.2 0.5 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EEQ36958.1 - 2e-06 27.3 0.2 0.00011 21.6 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 EEQ36958.1 - 0.00021 20.6 3.1 0.002 17.4 0.4 2.4 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.24 EEQ36958.1 - 0.00021 20.7 0.2 0.0025 17.2 0.2 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EEQ36958.1 - 0.00062 20.3 0.0 0.066 13.8 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ36958.1 - 0.0011 18.3 0.2 0.058 12.6 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ36958.1 - 0.0063 15.6 0.3 0.011 14.8 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein GDI PF00996.18 EEQ36958.1 - 0.17 10.4 0.0 0.67 8.4 0.0 1.8 2 0 0 2 2 2 0 GDP dissociation inhibitor zf_CCCH_4 PF18345.1 EEQ36959.1 - 6.2e-18 64.2 25.2 1.1e-05 25.3 3.9 4.3 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH PF00642.24 EEQ36959.1 - 1.4e-13 50.4 23.7 0.00099 19.0 1.1 4.2 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EEQ36959.1 - 9.2e-12 45.6 16.3 0.0068 17.1 0.6 4.1 1 1 3 4 4 4 4 Torus domain zf-CCCH_3 PF15663.5 EEQ36959.1 - 5.8e-05 23.3 10.1 0.019 15.2 5.2 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 EEQ36959.1 - 0.00027 20.6 9.6 0.0035 17.1 2.8 3.9 4 1 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EEQ36959.1 - 0.16 12.5 30.5 1.4 9.5 3.4 4.9 4 2 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-C3H1 PF10650.9 EEQ36959.1 - 0.5 10.1 15.9 1.6 8.6 0.5 4.2 4 0 0 4 4 4 0 Putative zinc-finger domain AWS PF17907.1 EEQ36959.1 - 5.9 7.0 9.4 0.73 9.9 0.4 3.2 3 0 0 3 3 3 0 AWS domain COG4 PF08318.12 EEQ36960.1 - 3.1e-86 289.5 0.4 3.1e-86 289.5 0.4 1.9 3 0 0 3 3 3 1 COG4 transport protein Vps53_N PF04100.12 EEQ36960.1 - 0.0093 15.0 6.1 0.013 14.5 3.3 2.4 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF1664 PF07889.12 EEQ36960.1 - 0.27 11.3 2.0 0.5 10.4 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_C1_2 PF03051.15 EEQ36961.1 - 2.2e-157 524.3 2.0 2.6e-157 524.1 2.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EEQ36961.1 - 1.4e-06 28.6 0.1 0.0023 18.1 0.1 2.4 2 0 0 2 2 2 2 Papain family cysteine protease RRM_1 PF00076.22 EEQ36962.1 - 2.3e-16 59.4 2.2 3.6e-09 36.3 0.0 3.8 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sds3 PF08598.11 EEQ36963.1 - 2.3e-23 83.4 0.8 2.3e-23 83.4 0.8 3.6 2 1 0 2 2 2 1 Sds3-like fn3_2 PF16893.5 EEQ36964.1 - 1.1e-37 128.1 0.2 2.3e-37 127.0 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EEQ36964.1 - 4e-25 87.5 0.1 7e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 EEQ36964.1 - 3.1e-14 53.1 0.1 7e-14 52.0 0.1 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EEQ36964.1 - 1.6e-08 34.4 0.0 3.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.8 EEQ36964.1 - 0.00034 20.8 0.2 0.00034 20.8 0.2 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3006) fn3 PF00041.21 EEQ36964.1 - 0.00093 19.5 0.1 0.0052 17.1 0.0 2.3 2 0 0 2 2 2 1 Fibronectin type III domain BRCT_2 PF16589.5 EEQ36964.1 - 0.026 14.9 0.0 0.093 13.2 0.0 2.0 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain ATP-synt_F PF01990.17 EEQ36965.1 - 3.9e-33 113.6 0.1 4.6e-33 113.4 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Transcrip_reg PF01709.20 EEQ36966.1 - 1.7e-73 247.0 3.4 1.9e-73 246.8 3.4 1.0 1 0 0 1 1 1 1 Transcriptional regulator MCM3AP_GANP PF16769.5 EEQ36966.1 - 0.054 11.8 0.0 0.075 11.3 0.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP Mito_carr PF00153.27 EEQ36967.1 - 2.5e-66 219.6 3.6 4.4e-25 87.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aminotran_3 PF00202.21 EEQ36968.1 - 1.9e-101 339.7 0.0 2.5e-101 339.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EEQ36968.1 - 0.0062 15.7 0.0 0.009 15.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II TRF PF08558.10 EEQ36969.1 - 8.1e-95 317.0 1.3 8.3e-95 316.9 0.0 1.7 2 0 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EEQ36969.1 - 5.4e-08 32.9 1.1 1.2e-07 31.8 1.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ36969.1 - 0.0065 16.7 0.3 0.018 15.3 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIIA PF03153.13 EEQ36969.1 - 4.4 7.2 62.3 0.28 11.1 56.0 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 EEQ36970.1 - 1.3e-22 79.6 19.7 6.2e-05 23.7 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ36970.1 - 1.3e-05 25.4 0.1 0.33 11.3 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ36970.1 - 0.0017 17.4 0.1 0.087 11.8 0.0 2.9 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein YEATS PF03366.16 EEQ36971.1 - 3.7e-22 78.1 0.0 6e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EEQ36971.1 - 2.8e-07 30.6 0.4 5.9e-07 29.6 0.4 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation YqeY PF09424.10 EEQ36972.1 - 1.1e-23 83.8 3.9 1.4e-23 83.6 3.9 1.1 1 0 0 1 1 1 1 Yqey-like protein THP2 PF09432.10 EEQ36972.1 - 0.0086 16.1 2.6 0.016 15.3 1.0 2.0 2 0 0 2 2 2 1 Tho complex subunit THP2 HNF-1_N PF04814.13 EEQ36972.1 - 0.021 15.4 1.0 0.027 15.1 1.0 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Coat_F PF07875.12 EEQ36972.1 - 0.023 14.9 0.2 5.3 7.4 0.1 2.5 2 0 0 2 2 2 0 Coat F domain IZUMO PF15005.6 EEQ36972.1 - 0.13 12.8 0.9 0.18 12.3 0.9 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated CemA PF03040.14 EEQ36972.1 - 0.29 11.0 2.7 0.37 10.7 2.1 1.3 1 1 0 1 1 1 0 CemA family DUF2175 PF09943.9 EEQ36972.1 - 3.2 8.1 5.7 1.8 8.9 1.9 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DHFR_1 PF00186.19 EEQ36973.1 - 3.6e-31 108.1 0.0 4.3e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrofolate reductase Pyridox_oxase_2 PF12766.7 EEQ36974.1 - 2.9e-31 108.0 0.0 5.1e-31 107.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 EEQ36974.1 - 5.1e-07 29.8 0.0 8.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 EEQ36974.1 - 0.11 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like AA_permease_2 PF13520.6 EEQ36975.1 - 8.8e-51 173.1 49.3 1.1e-50 172.7 49.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ36975.1 - 5.3e-14 51.7 42.7 5.3e-14 51.7 42.7 1.5 1 1 1 2 2 2 1 Amino acid permease HAT_KAT11 PF08214.11 EEQ36976.1 - 9.1e-83 278.4 0.0 1.5e-82 277.7 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein Apolipoprotein PF01442.18 EEQ36977.1 - 8.5e-08 32.3 9.5 1.2e-07 31.8 9.5 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EEQ36977.1 - 2.3e-05 24.6 14.6 0.0024 18.0 7.3 2.1 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) ISG65-75 PF11727.8 EEQ36977.1 - 0.00028 20.2 14.8 0.00039 19.8 14.8 1.4 1 0 0 1 1 1 1 Invariant surface glycoprotein DUF883 PF05957.13 EEQ36977.1 - 0.0065 17.0 12.3 0.046 14.3 7.9 2.7 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) CRISPR_Cse1 PF09481.10 EEQ36977.1 - 0.042 12.9 1.7 0.048 12.7 1.7 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) YtxH PF12732.7 EEQ36977.1 - 0.06 13.9 23.4 0.15 12.6 11.9 3.2 1 1 1 2 2 2 0 YtxH-like protein UPF0242 PF06785.11 EEQ36977.1 - 0.58 10.2 3.0 0.7 10.0 3.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LEA_4 PF02987.16 EEQ36977.1 - 0.68 10.1 32.2 0.17 12.0 12.0 4.8 4 1 1 5 5 5 0 Late embryogenesis abundant protein TMP_2 PF06791.13 EEQ36977.1 - 0.78 9.4 11.1 0.46 10.1 8.1 1.7 1 1 1 2 2 2 0 Prophage tail length tape measure protein TMF_TATA_bd PF12325.8 EEQ36977.1 - 0.87 9.8 6.9 7.5 6.8 6.6 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding V_ATPase_I PF01496.19 EEQ36977.1 - 2 6.2 4.0 2.2 6.1 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Oleosin PF01277.17 EEQ36977.1 - 2.9 7.7 3.8 4.3 7.1 0.4 2.5 1 1 1 3 3 3 0 Oleosin Alanine_zipper PF11839.8 EEQ36977.1 - 7.6 7.0 23.7 3.5 8.1 12.0 3.4 2 1 1 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DivIVA PF05103.13 EEQ36977.1 - 7.9 6.6 12.3 20 5.2 11.1 2.1 1 1 1 2 2 2 0 DivIVA protein Peroxin-13_N PF04088.13 EEQ36978.1 - 4e-51 173.1 0.8 6.7e-51 172.4 0.8 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EEQ36978.1 - 1.5e-07 31.0 0.0 3.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EEQ36978.1 - 1.1e-06 28.4 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ36978.1 - 1.7e-06 27.6 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 EEQ36978.1 - 0.00082 19.6 0.1 0.0024 18.1 0.1 1.8 1 0 0 1 1 1 1 Bacterial SH3 domain Pex2_Pex12 PF04757.14 EEQ36978.1 - 0.0014 18.2 0.1 0.0022 17.6 0.1 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region BCDHK_Adom3 PF10436.9 EEQ36979.1 - 1.3e-64 217.0 0.0 1.8e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EEQ36979.1 - 1.5e-12 48.0 0.0 3.3e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RAP1 PF07218.11 EEQ36979.1 - 0.94 7.7 4.0 1.3 7.2 4.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Herpes_pp85 PF04637.12 EEQ36979.1 - 3.6 5.9 7.9 5.4 5.3 7.0 1.6 2 0 0 2 2 2 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CN_hydrolase PF00795.22 EEQ36980.1 - 3.1e-47 161.1 0.0 3.8e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1687 PF07955.11 EEQ36981.1 - 1.3e-08 35.4 1.3 8.3e-08 32.8 1.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Chitin_synth_2 PF03142.15 EEQ36981.1 - 0.14 10.7 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Chitin synthase DUF5427 PF10310.9 EEQ36982.1 - 6.8e-108 361.6 13.9 8.3e-108 361.3 13.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) V-SNARE_C PF12352.8 EEQ36982.1 - 0.14 12.4 3.8 0.39 11.0 3.8 1.7 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus zf-RING_2 PF13639.6 EEQ36983.1 - 1.1 9.6 8.5 3.2 8.2 8.5 1.9 1 0 0 1 1 1 0 Ring finger domain Prok-RING_1 PF14446.6 EEQ36983.1 - 4.8 7.2 12.1 1.2 9.1 5.5 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PH_4 PF15404.6 EEQ36984.1 - 2.7e-60 203.3 0.3 1.2e-58 198.0 0.3 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EEQ36984.1 - 2.4e-07 31.2 0.2 0.00053 20.5 0.1 3.3 2 1 0 2 2 2 2 PH domain Spo7_2_N PF15407.6 EEQ36985.1 - 3.5e-22 77.8 0.0 9.5e-22 76.4 0.0 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 IBN_N PF03810.19 EEQ36986.1 - 4.9e-05 23.2 0.7 0.0006 19.7 0.0 3.4 3 1 0 3 3 3 1 Importin-beta N-terminal domain DNA_pol3_chi PF04364.13 EEQ36986.1 - 0.025 14.7 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC Xpo1 PF08389.12 EEQ36986.1 - 0.89 9.6 8.5 0.27 11.3 0.1 4.4 4 1 0 4 4 4 0 Exportin 1-like protein Sua5_yciO_yrdC PF01300.18 EEQ36987.1 - 1.3e-53 181.2 0.0 2.1e-53 180.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EEQ36987.1 - 3.2e-31 108.7 0.0 4.9e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding RANK_CRD_2 PF18278.1 EEQ36988.1 - 0.098 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Receptor activator of the NF-KB cysteine-rich repeat domain 2 E1-E2_ATPase PF00122.20 EEQ36989.1 - 8.6e-49 165.5 0.3 8.6e-49 165.5 0.3 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EEQ36989.1 - 8.9e-46 155.9 1.7 8.9e-46 155.9 1.7 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EEQ36989.1 - 3.5e-23 83.0 0.0 1.6e-22 80.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEQ36989.1 - 2.9e-14 52.5 0.0 7.2e-14 51.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EEQ36989.1 - 9.2e-14 51.3 0.0 2.5e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEQ36989.1 - 2.5e-08 34.0 2.0 3.6e-06 26.9 1.4 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 EEQ36989.1 - 0.01 15.7 0.1 0.03 14.3 0.1 1.8 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC NAD_binding_4 PF07993.12 EEQ36990.1 - 0.00045 19.5 0.0 0.0028 16.9 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EEQ36990.1 - 0.00053 19.9 0.0 0.0043 17.0 0.0 2.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EEQ36990.1 - 0.0012 18.3 0.0 0.002 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ36990.1 - 0.0075 15.3 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EEQ36990.1 - 0.18 11.2 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase TFIIA PF03153.13 EEQ36992.1 - 9.8 6.1 12.5 13 5.7 12.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-BED PF02892.15 EEQ36993.1 - 7e-07 29.2 0.1 7e-07 29.2 0.1 2.3 2 0 0 2 2 2 1 BED zinc finger Arc_trans_TRASH PF08394.10 EEQ36993.1 - 0.042 14.2 0.4 0.076 13.4 0.4 1.4 1 0 0 1 1 1 0 Archaeal TRASH domain Roughex PF06020.11 EEQ36995.1 - 0.038 13.1 7.6 0.055 12.6 7.6 1.3 1 0 0 1 1 1 0 Drosophila roughex protein ABC_tran_CTD PF16326.5 EEQ36995.1 - 0.045 14.0 1.1 0.14 12.4 1.1 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain Osmo_CC PF08946.10 EEQ36995.1 - 0.082 13.2 1.1 0.2 12.0 1.2 1.7 1 1 0 1 1 1 0 Osmosensory transporter coiled coil SMN PF06003.12 EEQ36995.1 - 0.38 10.0 6.4 0.27 10.5 4.2 1.9 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) SMYLE_N PF18615.1 EEQ36995.1 - 0.49 9.9 12.6 0.68 9.4 12.6 1.2 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain DUF4743 PF15916.5 EEQ36996.1 - 5.8e-13 48.9 0.0 9.6e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EEQ36996.1 - 3e-08 33.8 0.0 5.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Trypsin_2 PF13365.6 EEQ36997.1 - 2.1e-15 57.9 0.0 3.8e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 EEQ36997.1 - 3.2e-06 27.1 0.0 6.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Trypsin zf-H2C2_2 PF13465.6 EEQ36998.1 - 5.1e-05 23.5 17.8 7.1e-05 23.0 5.3 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EEQ36998.1 - 9.3e-05 22.7 14.2 0.0054 17.1 2.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ36998.1 - 0.0032 18.2 13.7 0.44 11.5 1.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger DUF1722 PF08349.11 EEQ36998.1 - 0.042 14.1 0.0 0.34 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) Zn_ribbon_recom PF13408.6 EEQ36998.1 - 0.32 11.6 4.4 0.68 10.5 4.4 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_jaz PF12171.8 EEQ36998.1 - 1.9 8.9 5.7 1.7 9.0 1.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 EEQ37000.1 - 2.9e-57 194.0 0.2 9.6e-41 139.9 0.1 3.8 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37000.1 - 4.3e-23 81.9 0.5 7.1e-20 71.4 0.0 3.3 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ37000.1 - 0.00033 19.7 0.2 0.00033 19.7 0.2 2.3 2 0 0 2 2 2 1 Haspin like kinase domain DUF3492 PF11997.8 EEQ37000.1 - 5.5 6.6 15.9 12 5.5 15.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) Ytp1 PF10355.9 EEQ37001.1 - 1.8e-106 355.4 8.2 2.7e-106 354.8 8.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EEQ37001.1 - 7.2e-20 70.7 6.7 7.2e-20 70.7 6.7 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) S-methyl_trans PF02574.16 EEQ37002.1 - 2.6e-66 224.2 0.0 2.9e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Citrate_bind PF16114.5 EEQ37002.1 - 0.032 13.8 0.1 0.27 10.7 0.0 2.1 1 1 1 2 2 2 0 ATP citrate lyase citrate-binding IRF-2BP1_2 PF11261.8 EEQ37002.1 - 0.14 11.7 1.1 0.28 10.8 0.1 1.9 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger MIF4G PF02854.19 EEQ37003.1 - 0.00096 18.8 0.6 0.0014 18.4 0.5 1.4 1 1 0 1 1 1 1 MIF4G domain DUF4106 PF13388.6 EEQ37003.1 - 0.093 11.9 0.3 0.12 11.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) MIF4G_like PF09088.11 EEQ37004.1 - 9.1e-51 172.3 0.6 1.7e-50 171.4 0.6 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EEQ37004.1 - 8.9e-47 159.8 1.6 2.2e-44 152.0 1.6 2.3 1 1 0 1 1 1 1 MIF4G like CsgA PF17334.2 EEQ37004.1 - 0.72 10.6 4.4 3.9 8.3 0.1 3.1 3 0 0 3 3 3 0 Minor curli fiber component A PSCyt2 PF07583.11 EEQ37004.1 - 0.75 9.7 3.0 23 4.8 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1549) ABC_tran PF00005.27 EEQ37005.1 - 1.6e-16 61.0 0.0 4.2e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EEQ37005.1 - 7.7e-10 39.1 2.2 3.8e-05 23.7 0.8 2.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ37005.1 - 5.9e-05 22.6 1.3 0.27 10.7 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEQ37005.1 - 0.00021 21.9 2.0 0.0028 18.2 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEQ37005.1 - 0.00089 19.0 0.2 0.0019 17.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ37005.1 - 0.0015 18.5 0.1 0.0034 17.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EEQ37005.1 - 0.0024 17.6 0.0 0.0029 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EEQ37005.1 - 0.0066 17.0 0.1 0.039 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EEQ37005.1 - 0.0072 16.7 0.1 0.046 14.1 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ37005.1 - 0.053 13.8 0.2 0.72 10.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EEQ37005.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEQ37005.1 - 0.066 13.4 0.3 0.34 11.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EEQ37005.1 - 0.1 12.6 0.0 0.73 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EEQ37005.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_13 PF13166.6 EEQ37005.1 - 0.13 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain UspB PF10625.9 EEQ37006.1 - 0.11 12.5 1.9 0.23 11.4 1.9 1.6 1 0 0 1 1 1 0 Universal stress protein B (UspB) NDK PF00334.19 EEQ37007.1 - 2.9e-53 179.5 0.0 3.3e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4014 PF13198.6 EEQ37008.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4014) WD40 PF00400.32 EEQ37009.1 - 1.4e-13 51.1 11.6 0.033 15.1 0.1 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat Apt1 PF10351.9 EEQ37009.1 - 6.7 5.4 14.0 1.6 7.5 7.7 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain RabGAP-TBC PF00566.18 EEQ37010.1 - 4.1e-14 52.8 1.6 1.2e-13 51.3 1.6 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain TauD PF02668.16 EEQ37011.1 - 1.8e-40 139.5 0.0 2.4e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EEQ37011.1 - 6.6e-14 52.3 0.2 1.5e-13 51.2 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) Aldo_ket_red PF00248.21 EEQ37012.1 - 5.6e-47 160.3 0.0 8e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2380 PF09533.10 EEQ37012.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) T2SSE PF00437.20 EEQ37013.1 - 2.1e-05 23.8 0.9 6.6e-05 22.1 0.0 2.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_30 PF13604.6 EEQ37013.1 - 4.8e-05 23.2 0.1 0.0013 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ37013.1 - 8.3e-05 22.9 0.0 0.00047 20.4 0.0 2.3 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 EEQ37013.1 - 0.00014 22.1 0.5 0.57 10.4 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EEQ37013.1 - 0.0003 21.2 0.0 0.0012 19.3 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain ATG16 PF08614.11 EEQ37013.1 - 0.00037 20.8 40.1 0.059 13.6 12.0 3.6 1 1 2 3 3 2 2 Autophagy protein 16 (ATG16) ABC_tran PF00005.27 EEQ37013.1 - 0.0004 20.9 1.0 0.0004 20.9 1.0 3.7 2 2 0 2 2 1 1 ABC transporter AAA_14 PF13173.6 EEQ37013.1 - 0.00057 19.9 0.0 0.0026 17.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain Golgin_A5 PF09787.9 EEQ37013.1 - 0.0011 18.5 50.3 0.017 14.6 24.8 3.3 1 1 2 3 3 3 2 Golgin subfamily A member 5 TelA PF05816.11 EEQ37013.1 - 0.0014 17.7 13.4 0.0014 17.7 13.4 3.0 2 1 0 3 3 3 1 Toxic anion resistance protein (TelA) AAA_19 PF13245.6 EEQ37013.1 - 0.0054 17.1 6.9 0.013 15.8 3.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEQ37013.1 - 0.0066 16.0 1.4 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EEQ37013.1 - 0.0071 15.7 0.2 0.24 10.7 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.29 EEQ37013.1 - 0.016 15.6 0.1 0.095 13.1 0.0 2.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EEQ37013.1 - 0.031 14.3 0.3 0.031 14.3 0.3 3.0 2 1 0 2 2 1 0 Type III restriction enzyme, res subunit AAA_33 PF13671.6 EEQ37013.1 - 0.047 13.9 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ37013.1 - 0.047 13.7 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE HrpB7 PF09486.10 EEQ37013.1 - 0.048 14.0 7.4 6.1 7.2 3.0 3.3 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) AAA_5 PF07728.14 EEQ37013.1 - 0.055 13.5 0.1 0.48 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Nore1-SARAH PF16517.5 EEQ37013.1 - 0.062 13.2 2.1 0.16 11.9 0.6 2.6 1 1 1 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain AAA_18 PF13238.6 EEQ37013.1 - 0.16 12.5 3.8 0.73 10.4 0.0 3.4 3 0 0 3 3 3 0 AAA domain Spc7 PF08317.11 EEQ37013.1 - 0.41 9.5 47.5 0.06 12.2 9.8 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein Fib_alpha PF08702.10 EEQ37013.1 - 0.45 10.7 36.5 1.3 9.2 7.3 4.6 1 1 4 5 5 5 0 Fibrinogen alpha/beta chain family DUF4200 PF13863.6 EEQ37013.1 - 1 9.8 48.3 0.04 14.3 8.4 4.8 1 1 2 5 5 5 0 Domain of unknown function (DUF4200) DivIVA PF05103.13 EEQ37013.1 - 1.8 8.7 33.9 1.5 8.9 2.3 5.2 1 1 2 3 3 3 0 DivIVA protein SlyX PF04102.12 EEQ37013.1 - 2.1 9.0 28.2 0.57 10.8 2.4 6.0 3 2 3 6 6 6 0 SlyX MMR_HSR1 PF01926.23 EEQ37013.1 - 3.7 7.7 6.9 1.1 9.4 0.7 3.0 2 2 0 2 2 2 0 50S ribosome-binding GTPase P16-Arc PF04699.14 EEQ37014.1 - 9.9e-45 152.7 0.0 1.7e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF1892 PF08987.10 EEQ37015.1 - 2.4e-13 50.2 0.7 2.4e-13 50.2 0.7 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1892) PDCD2_C PF04194.13 EEQ37015.1 - 0.071 13.2 0.0 0.083 13.0 0.0 1.3 1 1 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain PGI PF00342.19 EEQ37016.1 - 2.1e-245 814.9 4.1 2.4e-245 814.7 4.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Mhr1 PF12829.7 EEQ37016.1 - 0.08 13.0 0.0 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination Zn_clus PF00172.18 EEQ37019.1 - 0.00052 20.1 8.4 0.00092 19.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cation_efflux PF01545.21 EEQ37020.1 - 1.6e-22 80.3 12.5 2e-22 79.9 12.5 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EEQ37020.1 - 1.4e-05 25.1 0.0 2.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter WD40 PF00400.32 EEQ37021.1 - 1.8e-22 79.2 14.3 2.2e-06 28.3 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37021.1 - 6.1e-12 45.7 0.0 2.1e-06 27.9 0.0 4.9 4 2 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ37021.1 - 0.026 13.5 0.3 11 4.9 0.0 3.3 3 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EEQ37021.1 - 0.034 12.5 0.0 0.077 11.3 0.0 1.5 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Gmad1 PF10647.9 EEQ37021.1 - 0.04 13.7 0.0 2.2 8.0 0.0 2.9 3 1 2 5 5 4 0 Lipoprotein LpqB beta-propeller domain UPF0121 PF03661.13 EEQ37022.1 - 0.00015 21.2 7.9 0.00015 21.2 7.9 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0121) CDP-OH_P_transf PF01066.21 EEQ37022.1 - 2.5 8.9 5.5 12 6.7 5.5 2.2 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase DASH_Dad3 PF08656.10 EEQ37023.1 - 8.6e-24 83.4 2.2 1.3e-23 82.9 2.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF1902 PF08972.11 EEQ37023.1 - 0.11 12.5 0.3 0.62 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Lyase_1 PF00206.20 EEQ37024.1 - 3.1e-23 82.6 0.0 5e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EEQ37024.1 - 2.4e-17 63.2 0.0 8.2e-17 61.5 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus GcnA_N PF18229.1 EEQ37024.1 - 0.05 13.6 0.7 0.21 11.6 0.2 2.2 2 0 0 2 2 2 0 N-acetyl-beta-D-glucosaminidase N-terminal domain DUF1331 PF07048.11 EEQ37024.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Mid2 PF04478.12 EEQ37025.1 - 1e-09 38.4 1.0 1e-09 38.4 1.0 2.6 2 1 1 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 EEQ37025.1 - 1.4e-05 24.4 3.7 4.4e-05 22.8 3.7 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PAP1 PF08601.10 EEQ37025.1 - 0.019 14.7 31.6 0.024 14.4 31.6 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Mucin15 PF15672.5 EEQ37025.1 - 0.53 9.7 31.7 0.82 9.1 31.7 1.2 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 MFS_1 PF07690.16 EEQ37026.1 - 1e-25 90.4 38.5 3.3e-19 69.0 12.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ37026.1 - 3.2e-07 29.6 3.6 3.2e-07 29.6 3.6 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter OATP PF03137.20 EEQ37026.1 - 0.00012 20.5 1.6 0.0084 14.4 0.6 2.9 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family UNC-93 PF05978.16 EEQ37026.1 - 0.023 14.4 1.0 0.023 14.4 1.0 2.0 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 7TM_GPCR_Sri PF10327.9 EEQ37026.1 - 0.97 8.6 11.8 0.022 14.0 3.3 2.5 3 1 0 3 3 3 0 Serpentine type 7TM GPCR chemoreceptor Sri MFS_1 PF07690.16 EEQ37027.1 - 2.2e-30 105.8 34.9 7.1e-29 100.8 13.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ37027.1 - 8.9e-09 34.7 3.9 8.9e-09 34.7 3.9 3.6 2 2 1 4 4 4 1 Sugar (and other) transporter UNC-93 PF05978.16 EEQ37027.1 - 0.0038 16.9 1.0 0.0038 16.9 1.0 3.7 3 1 1 4 4 4 2 Ion channel regulatory protein UNC-93 Abhydrolase_1 PF00561.20 EEQ37029.1 - 4.2e-19 69.2 0.1 1.4e-17 64.2 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ37029.1 - 3.6e-15 57.2 2.4 4.8e-15 56.8 2.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ37029.1 - 0.00013 21.4 0.0 0.00078 18.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EEQ37029.1 - 0.0027 17.9 0.0 0.0044 17.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EEQ37029.1 - 0.0074 16.0 0.2 0.0094 15.6 0.2 1.2 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 EEQ37029.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase BAR PF03114.18 EEQ37030.1 - 7.2e-60 202.6 6.9 9.4e-60 202.2 6.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EEQ37030.1 - 6.2e-14 51.3 0.1 1.3e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ37030.1 - 1.5e-12 47.1 0.1 2.6e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ37030.1 - 1.7e-06 27.6 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Collagen PF01391.18 EEQ37030.1 - 0.0051 16.6 19.3 0.03 14.1 19.3 2.1 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) Vps5 PF09325.10 EEQ37030.1 - 0.54 9.8 6.2 0.23 11.0 3.2 1.7 2 0 0 2 2 2 0 Vps5 C terminal like ANAPC1 PF12859.7 EEQ37031.1 - 4 8.0 6.6 0.56 10.8 0.5 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 1 IDO PF01231.18 EEQ37032.1 - 7.9e-153 509.3 0.0 9e-153 509.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase tRNA-synt_His PF13393.6 EEQ37033.1 - 5.3e-41 140.9 0.1 2e-34 119.2 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EEQ37033.1 - 1.3e-11 44.5 0.0 2.6e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EEQ37033.1 - 0.0045 16.5 0.0 0.011 15.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EEQ37033.1 - 0.039 13.0 0.0 0.22 10.6 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) SPOR PF05036.13 EEQ37033.1 - 0.066 13.6 2.6 4.3 7.8 0.6 3.1 2 1 0 2 2 2 0 Sporulation related domain FA_desaturase PF00487.24 EEQ37034.1 - 3.7e-12 46.6 4.5 4.7e-12 46.3 4.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EEQ37035.1 - 5.3e-16 57.8 0.1 8.3e-16 57.2 0.1 1.3 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) FA_desaturase PF00487.24 EEQ37035.1 - 1.5e-11 44.6 1.7 1.5e-11 44.6 1.7 1.5 2 0 0 2 2 2 1 Fatty acid desaturase DUF2536 PF10750.9 EEQ37035.1 - 0.0083 16.0 0.0 0.42 10.6 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2536) EST1_DNA_bind PF10373.9 EEQ37036.1 - 1.4e-41 142.8 3.9 1.4e-41 142.8 3.9 2.6 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EEQ37036.1 - 1.2e-11 45.4 0.4 1.2e-11 45.4 0.4 2.4 3 0 0 3 3 3 1 Telomerase activating protein Est1 APP_N PF02177.16 EEQ37036.1 - 0.01 16.2 0.1 0.29 11.5 0.0 2.6 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding DUF228 PF02989.14 EEQ37036.1 - 0.052 13.3 0.3 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Peptidase_C97 PF05903.14 EEQ37037.1 - 2e-39 134.9 0.0 2.3e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EEQ37037.1 - 0.077 13.3 0.1 0.12 12.6 0.1 1.4 1 0 0 1 1 1 0 Lecithin retinol acyltransferase Wtap PF17098.5 EEQ37038.1 - 0.00073 19.5 12.7 0.0017 18.3 12.7 1.8 1 1 0 1 1 1 1 WTAP/Mum2p family Virulence_fact PF13769.6 EEQ37039.1 - 0.34 11.1 3.3 0.35 11.1 0.3 2.3 2 0 0 2 2 2 0 Virulence factor Tim17 PF02466.19 EEQ37040.1 - 1.3e-07 31.9 0.9 3.1e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family La PF05383.17 EEQ37041.1 - 9.7e-16 57.6 0.6 1.8e-15 56.7 0.2 1.7 2 0 0 2 2 2 1 La domain HCO3_cotransp PF00955.21 EEQ37042.1 - 8.2e-81 272.3 10.1 1.1e-44 153.1 3.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family Asparaginase_2 PF01112.18 EEQ37043.1 - 9.4e-16 57.7 1.9 3.1e-14 52.7 1.9 2.6 1 1 0 1 1 1 1 Asparaginase Ribosomal_L24e PF01246.20 EEQ37044.1 - 5.1e-30 103.5 0.2 5.1e-30 103.5 0.2 2.2 2 1 0 2 2 2 1 Ribosomal protein L24e DASH_Spc34 PF08657.10 EEQ37045.1 - 3.1e-43 148.4 5.3 2.7e-21 76.5 5.2 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 Sec34 PF04136.15 EEQ37045.1 - 0.035 14.0 0.1 0.06 13.2 0.1 1.5 1 0 0 1 1 1 0 Sec34-like family Lebercilin PF15619.6 EEQ37045.1 - 0.063 12.9 4.6 0.16 11.6 0.2 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 EEQ37045.1 - 0.1 11.9 2.0 0.14 11.4 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 EEQ37045.1 - 0.15 12.3 1.1 0.33 11.2 0.2 2.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Flu_NS2 PF00601.19 EEQ37045.1 - 0.2 12.0 2.1 0.4 11.0 0.5 2.2 3 0 0 3 3 3 0 Influenza non-structural protein (NS2) Bap31_Bap29_C PF18035.1 EEQ37045.1 - 0.25 11.4 0.2 0.25 11.4 0.2 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain TMPIT PF07851.13 EEQ37045.1 - 0.27 10.4 0.4 0.37 10.0 0.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein Med9 PF07544.13 EEQ37045.1 - 0.67 10.1 4.2 8.4 6.6 1.6 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Peptidase_M22 PF00814.25 EEQ37046.1 - 2.5e-84 283.2 0.0 3.1e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EEQ37046.1 - 0.002 17.9 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 Carbamoyltransferase N-terminus MutL PF13941.6 EEQ37046.1 - 0.029 13.0 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 MutL protein CUE PF02845.16 EEQ37047.1 - 3.1e-12 45.9 0.4 5.8e-05 22.7 0.1 2.8 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 EEQ37047.1 - 4.7e-09 36.5 0.1 1.1e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 Smr domain P22_Cro PF14549.6 EEQ37047.1 - 0.17 11.8 0.6 0.43 10.5 0.6 1.6 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro PH PF00169.29 EEQ37048.1 - 2.9e-24 85.6 6.7 6e-12 46.0 3.7 2.1 2 0 0 2 2 2 2 PH domain PH_8 PF15409.6 EEQ37048.1 - 1.7e-09 37.9 6.2 1.5e-08 34.8 2.8 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EEQ37048.1 - 3.1e-06 27.6 16.1 0.0016 18.9 8.6 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_2 PF08458.10 EEQ37048.1 - 0.0033 17.7 1.1 0.75 10.2 0.1 2.4 2 0 0 2 2 2 2 Plant pleckstrin homology-like region PH_13 PF16652.5 EEQ37048.1 - 0.0084 15.9 1.4 2 8.2 0.1 2.4 2 1 0 2 2 2 2 Pleckstrin homology domain DUF2550 PF10739.9 EEQ37048.1 - 0.011 15.7 0.4 0.022 14.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) Capsid_N PF16903.5 EEQ37048.1 - 0.042 13.5 0.2 0.073 12.7 0.2 1.4 1 1 0 1 1 1 0 Major capsid protein N-terminus IQ_SEC7_PH PF16453.5 EEQ37048.1 - 0.049 13.6 0.4 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 PH domain PH_9 PF15410.6 EEQ37048.1 - 0.15 12.5 7.6 1.8 8.9 0.2 3.0 2 2 0 2 2 2 0 Pleckstrin homology domain Rep_fac_C PF08542.11 EEQ37049.1 - 2.9e-15 56.5 0.0 7.5e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EEQ37049.1 - 5.3e-11 42.6 0.1 9.3e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.13 EEQ37049.1 - 9.5e-08 32.0 0.1 1.7e-07 31.2 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 EEQ37049.1 - 7.5e-07 29.4 0.0 1.9e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EEQ37049.1 - 2.5e-06 27.9 0.2 6.1e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) L27_1 PF09058.10 EEQ37049.1 - 0.0058 16.6 0.1 0.037 14.0 0.0 2.3 2 0 0 2 2 2 1 L27_1 DEAD PF00270.29 EEQ37049.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase IF-2 PF11987.8 EEQ37049.1 - 0.051 13.7 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 Translation-initiation factor 2 DDE_3 PF13358.6 EEQ37049.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 DDE superfamily endonuclease Mid1 PF12929.7 EEQ37050.1 - 1.7e-119 399.8 4.9 2.2e-119 399.5 4.9 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EEQ37050.1 - 0.67 10.6 9.2 7.8 7.2 9.2 2.5 1 1 0 1 1 1 0 Fz domain Usp PF00582.26 EEQ37051.1 - 0.037 14.5 0.0 0.53 10.8 0.0 2.7 2 1 0 2 2 2 0 Universal stress protein family Med10 PF09748.9 EEQ37053.1 - 1.9e-33 115.0 0.0 2.2e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Sugar_tr PF00083.24 EEQ37055.1 - 4.7e-80 269.6 18.5 5.6e-80 269.4 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ37055.1 - 6.8e-21 74.6 16.8 1.2e-20 73.8 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ37055.1 - 2.4e-06 26.3 0.6 2.4e-06 26.3 0.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EEQ37055.1 - 9.1e-06 24.5 0.7 9.1e-06 24.5 0.7 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.24 EEQ37056.1 - 5.5e-78 262.8 14.2 6.4e-78 262.6 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ37056.1 - 5.2e-17 61.8 15.9 1.7e-16 60.1 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ37056.1 - 4.6e-06 25.5 12.0 0.00024 19.8 0.1 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EEQ37056.1 - 0.00045 18.8 1.7 0.00045 18.8 1.7 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Cellulase PF00150.18 EEQ37057.1 - 5.6e-32 111.3 2.5 8.3e-32 110.7 2.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_3_C PF01915.22 EEQ37058.1 - 2.2e-64 217.2 0.0 4.7e-64 216.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EEQ37058.1 - 2.1e-50 171.9 0.0 4.6e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain PA14 PF07691.12 EEQ37058.1 - 1.1e-20 73.9 0.0 2.2e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Fn3-like PF14310.6 EEQ37058.1 - 1.2e-19 70.2 0.2 1.2e-19 70.2 0.2 2.3 3 0 0 3 3 3 1 Fibronectin type III-like domain GLEYA PF10528.9 EEQ37058.1 - 0.029 14.8 0.0 0.082 13.3 0.0 1.8 1 0 0 1 1 1 0 GLEYA domain DUF11 PF01345.18 EEQ37058.1 - 0.13 12.5 0.7 0.47 10.8 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF11 GLTP PF08718.11 EEQ37060.1 - 1.1e-45 155.6 0.0 1.4e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Hormone_2 PF00123.20 EEQ37060.1 - 0.033 14.1 1.1 0.17 11.8 0.2 2.2 2 0 0 2 2 2 0 Peptide hormone Complex1_LYR_2 PF13233.6 EEQ37061.1 - 2.1e-18 66.8 0.0 2.9e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EEQ37061.1 - 6.1e-09 35.8 0.1 1.6e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 EEQ37061.1 - 0.048 14.3 0.0 0.068 13.8 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like zf-rbx1 PF12678.7 EEQ37062.1 - 3.1e-08 33.8 5.5 5.6e-08 32.9 5.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ37062.1 - 7.6e-07 29.4 11.5 6.8e-06 26.3 11.5 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ37062.1 - 4.3e-06 26.5 5.4 4.3e-06 26.5 5.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ37062.1 - 2.3e-05 24.1 6.8 4.6e-05 23.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ37062.1 - 3.4e-05 23.7 7.2 7.1e-05 22.7 7.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EEQ37062.1 - 0.0001 22.0 4.8 0.0032 17.2 1.1 2.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EEQ37062.1 - 0.00013 21.9 9.8 0.00072 19.5 9.5 2.5 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EEQ37062.1 - 0.0016 18.3 4.6 0.0016 18.3 4.6 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EEQ37062.1 - 0.01 15.7 4.8 0.01 15.7 4.8 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEQ37062.1 - 0.012 15.2 5.0 0.027 14.1 5.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EEQ37062.1 - 0.028 14.5 3.2 0.062 13.4 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EEQ37062.1 - 0.25 11.2 9.0 0.87 9.5 9.0 1.9 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 EEQ37062.1 - 0.76 10.0 6.0 2.4 8.4 6.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EEQ37062.1 - 1.6 8.9 6.0 1.1 9.5 3.1 2.2 2 0 0 2 2 2 0 RING-variant domain WW PF00397.26 EEQ37063.1 - 0.00014 21.8 0.2 0.0003 20.8 0.2 1.6 1 0 0 1 1 1 1 WW domain FF PF01846.19 EEQ37063.1 - 0.00017 21.7 0.1 0.00082 19.5 0.1 2.3 1 0 0 1 1 1 1 FF domain BUD22 PF09073.10 EEQ37063.1 - 0.052 12.9 24.5 0.073 12.4 24.5 1.3 1 0 0 1 1 1 0 BUD22 DUF4045 PF13254.6 EEQ37063.1 - 0.28 10.8 11.0 0.44 10.1 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Nop14 PF04147.12 EEQ37063.1 - 2.1 6.5 30.8 3.1 5.9 30.8 1.3 1 0 0 1 1 1 0 Nop14-like family Bindin PF02084.15 EEQ37063.1 - 2.3 8.4 11.6 1.1 9.5 2.8 2.3 1 1 1 2 2 2 0 Bindin NCA2 PF08637.10 EEQ37064.1 - 1.4e-90 303.4 3.6 1.9e-90 303.0 3.6 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 HSP20 PF00011.21 EEQ37064.1 - 0.0091 16.1 0.1 0.026 14.7 0.0 1.8 2 0 0 2 2 2 1 Hsp20/alpha crystallin family Proteasome PF00227.26 EEQ37066.1 - 6.4e-59 198.6 0.2 7.8e-59 198.4 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ37066.1 - 2.2e-13 49.6 0.3 3.7e-13 48.9 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Tmemb_170 PF10190.9 EEQ37067.1 - 2.2e-15 56.9 12.4 6e-15 55.5 12.4 1.6 1 1 0 1 1 1 1 Putative transmembrane protein 170 Peptidase_C48 PF02902.19 EEQ37069.1 - 1.6e-13 51.0 0.3 5.3e-13 49.3 0.3 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_M24 PF00557.24 EEQ37070.1 - 4.2e-49 167.1 0.0 6.7e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EEQ37070.1 - 2.9e-34 117.5 0.0 4.6e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Band_7 PF01145.25 EEQ37071.1 - 1.4e-22 80.6 8.2 2.4e-22 79.8 7.8 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EEQ37071.1 - 0.00073 18.7 3.4 0.00099 18.3 3.4 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Atg14 PF10186.9 EEQ37071.1 - 0.12 11.4 2.1 0.17 10.9 2.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Peptidase_S66 PF02016.15 EEQ37071.1 - 0.15 12.2 0.2 0.32 11.1 0.2 1.6 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain VIT1 PF01988.19 EEQ37073.1 - 6e-63 212.6 1.1 8.2e-63 212.1 1.1 1.2 1 0 0 1 1 1 1 VIT family GARP PF16731.5 EEQ37073.1 - 0.038 13.7 0.9 0.054 13.2 0.9 1.2 1 0 0 1 1 1 0 Glutamic acid/alanine-rich protein of Trypanosoma STI1 PF17830.1 EEQ37074.1 - 3.7e-06 26.8 4.8 1.3 9.0 0.0 6.2 3 2 6 9 9 9 5 STI1 domain DnaI_N PF07319.11 EEQ37074.1 - 0.12 13.0 4.1 22 5.8 0.1 4.6 1 1 3 4 4 4 0 Primosomal protein DnaI N-terminus GerD PF17898.1 EEQ37074.1 - 2.2 8.3 23.5 5 7.1 7.5 5.6 1 1 2 3 3 3 0 Spore germination GerD central core domain SPATA3 PF15662.5 EEQ37074.1 - 6.4 7.4 36.1 6.1 7.4 3.8 3.4 1 1 2 3 3 3 0 Spermatogenesis-associated protein 3 family Flo11 PF10182.9 EEQ37076.1 - 1.2e-128 424.7 31.8 2.6e-43 147.7 5.2 3.7 3 0 0 3 3 3 3 Flo11 domain Flocculin_t3 PF13928.6 EEQ37076.1 - 4.8e-28 97.4 138.2 4.1e-11 43.2 26.5 21.1 13 4 3 16 16 16 4 Flocculin type 3 repeat GAD-like PF08887.11 EEQ37076.1 - 0.0012 18.6 6.0 1.5 8.6 0.2 3.4 3 0 0 3 3 3 2 GAD-like domain FANCL_C PF11793.8 EEQ37076.1 - 0.0071 16.5 2.9 30 4.9 0.0 4.4 4 0 0 4 4 4 1 FANCL C-terminal domain Sugar_tr PF00083.24 EEQ37077.1 - 2.9e-131 438.5 20.3 3.3e-131 438.3 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ37077.1 - 4.4e-26 91.6 25.2 5.7e-26 91.3 23.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fasciclin PF02469.22 EEQ37078.1 - 4.8e-14 52.7 3.7 2.3e-07 31.1 0.2 3.6 3 2 0 3 3 3 2 Fasciclin domain Fasciclin PF02469.22 EEQ37079.1 - 1.2e-08 35.2 0.0 0.00011 22.4 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain RRM_1 PF00076.22 EEQ37080.1 - 1.4e-15 56.9 0.0 2.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EEQ37080.1 - 0.0053 16.8 0.0 0.02 15.0 0.0 2.0 1 1 1 2 2 2 1 Limkain b1 FliD_N PF02465.18 EEQ37080.1 - 0.072 13.8 0.5 0.15 12.8 0.5 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus RRM_5 PF13893.6 EEQ37080.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hyphal_reg_CWP PF11765.8 EEQ37081.1 - 2.2e-47 161.6 3.8 2.8e-47 161.3 3.8 1.0 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal MFS_1 PF07690.16 EEQ37084.1 - 1.9e-28 99.4 28.0 1.9e-28 99.4 28.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ37084.1 - 5.1e-08 32.2 7.7 5.1e-08 32.2 7.7 2.6 2 1 1 3 3 3 2 Sugar (and other) transporter Amidase PF01425.21 EEQ37085.1 - 2.6e-85 287.1 0.0 4.1e-85 286.4 0.0 1.3 1 1 0 1 1 1 1 Amidase Fungal_trans_2 PF11951.8 EEQ37086.1 - 0.012 14.4 2.0 0.052 12.4 0.1 2.2 2 1 0 2 2 2 0 Fungal specific transcription factor domain Gpr1_Fun34_YaaH PF01184.19 EEQ37087.1 - 4.4e-75 251.8 24.0 5.1e-75 251.6 24.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family TMEM247 PF15444.6 EEQ37087.1 - 2 8.4 4.2 2.8 7.9 4.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 CRAL_TRIO PF00650.20 EEQ37088.1 - 2.1e-29 102.3 0.0 6.7e-29 100.7 0.0 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ37088.1 - 0.0002 21.5 0.4 0.01 16.0 0.0 2.7 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEQ37088.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2156 PF09924.9 EEQ37088.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) adh_short_C2 PF13561.6 EEQ37089.1 - 1.3e-38 132.9 0.1 1.6e-38 132.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ37089.1 - 2.1e-37 128.5 0.0 2.6e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ37089.1 - 1.2e-10 41.6 0.1 1.8e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ37089.1 - 0.0063 16.0 0.1 0.018 14.5 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 EEQ37089.1 - 0.028 14.5 0.1 0.32 11.1 0.1 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EEQ37089.1 - 0.08 12.3 0.0 4.8 6.5 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_transf_21 PF13506.6 EEQ37090.1 - 5.8e-19 68.2 0.0 2e-13 50.2 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EEQ37090.1 - 1.8e-12 47.6 0.0 4.7e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EEQ37090.1 - 0.068 13.0 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 2 Carn_acyltransf PF00755.20 EEQ37091.1 - 2.9e-186 620.6 0.1 3.3e-186 620.4 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ATG11 PF10377.9 EEQ37092.1 - 5.7e-37 126.7 0.0 5.7e-37 126.7 0.0 4.7 3 1 0 3 3 3 1 Autophagy-related protein 11 Pribosyltran_N PF13793.6 EEQ37093.1 - 1.3e-38 131.5 0.3 2.5e-37 127.4 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EEQ37093.1 - 3.4e-38 131.5 0.3 1.8e-35 122.6 0.1 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EEQ37093.1 - 1.8e-16 60.1 0.7 4.5e-16 58.8 0.3 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEQ37093.1 - 0.0026 17.2 0.1 0.0046 16.4 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase ILVD_EDD PF00920.21 EEQ37094.1 - 1.1e-111 374.0 2.4 1.4e-111 373.7 2.4 1.0 1 0 0 1 1 1 1 Dehydratase family HMGL-like PF00682.19 EEQ37096.1 - 5.2e-84 281.9 0.1 7.7e-84 281.4 0.1 1.3 1 0 0 1 1 1 1 HMGL-like FliG_N PF14842.6 EEQ37096.1 - 0.034 14.7 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain EXS PF03124.14 EEQ37097.1 - 1.1e-101 340.5 25.7 1.3e-101 340.2 25.7 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EEQ37097.1 - 5.3e-27 95.7 5.0 5.3e-27 95.7 5.0 2.1 2 0 0 2 2 2 1 SPX domain Mg296 PF09644.10 EEQ37097.1 - 4.4 7.5 7.1 3.6 7.7 1.4 2.9 2 1 1 3 3 3 0 Mg296 protein DSPc PF00782.20 EEQ37098.1 - 6.9e-10 38.9 0.0 1.9e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEQ37098.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Abhydrolase_4 PF08386.10 EEQ37098.1 - 0.03 14.4 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_1 PF00561.20 EEQ37098.1 - 0.036 13.7 0.0 0.25 10.9 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ37099.1 - 0.00054 20.6 0.0 0.00082 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ37099.1 - 0.0027 17.4 0.0 0.0059 16.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ37099.1 - 0.034 13.4 0.0 0.061 12.6 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PhoLip_ATPase_N PF16209.5 EEQ37100.1 - 7.2e-19 67.3 4.8 1.2e-18 66.5 4.8 1.3 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EEQ37100.1 - 1.4e-05 24.7 0.2 3e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Prot_ATP_ID_OB PF16450.5 EEQ37100.1 - 0.006 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain PhoLip_ATPase_C PF16212.5 EEQ37101.1 - 3.2e-48 164.7 19.4 3.2e-48 164.7 19.4 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EEQ37101.1 - 1.6e-12 48.1 0.3 6.9e-06 26.5 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ37101.1 - 5.4e-10 39.2 0.1 3.4e-08 33.5 0.0 2.8 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEQ37101.1 - 0.002 17.9 0.1 0.0077 16.0 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ37101.1 - 0.075 12.5 0.2 0.075 12.5 0.2 2.6 2 0 0 2 2 2 0 E1-E2 ATPase DUF2070 PF09843.9 EEQ37101.1 - 1.7 6.8 13.3 3 6.0 13.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Rgp1 PF08737.10 EEQ37102.1 - 0.065 12.4 8.8 0.11 11.6 8.8 1.3 1 0 0 1 1 1 0 Rgp1 Ndc1_Nup PF09531.10 EEQ37102.1 - 0.4 9.3 10.0 0.44 9.2 10.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EEQ37102.1 - 0.91 8.2 9.0 1.1 7.9 9.0 1.2 1 0 0 1 1 1 0 Presenilin SRP-alpha_N PF04086.13 EEQ37102.1 - 4.9 7.0 18.8 7.4 6.4 18.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF4638 PF15472.6 EEQ37102.1 - 8.7 6.0 15.2 24 4.6 15.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4638) ATP-synt_ab PF00006.25 EEQ37103.1 - 2e-71 240.0 0.0 2.7e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EEQ37103.1 - 8.3e-48 161.9 1.2 1.3e-47 161.3 1.2 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EEQ37103.1 - 0.00051 20.5 0.0 0.0014 19.1 0.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Ndc1_Nup PF09531.10 EEQ37104.1 - 7.9 5.0 14.2 14 4.2 14.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Acetyltransf_10 PF13673.7 EEQ37105.1 - 0.12 12.3 0.0 0.56 10.2 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ37105.1 - 0.13 12.7 0.0 0.26 11.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ERAP1_C PF11838.8 EEQ37106.1 - 7.9e-38 130.8 0.0 9.9e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain HEAT_2 PF13646.6 EEQ37106.1 - 0.026 14.9 0.0 0.063 13.7 0.0 1.6 1 1 0 1 1 1 0 HEAT repeats Peptidase_M1 PF01433.20 EEQ37107.1 - 9.9e-87 290.1 2.0 1.4e-86 289.6 2.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EEQ37107.1 - 1.3e-52 178.7 0.0 2.2e-52 178.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EEQ37107.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Rotamase PF00639.21 EEQ37109.1 - 1.2e-20 74.2 0.0 2.3e-20 73.4 0.0 1.5 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EEQ37109.1 - 7.9e-17 61.9 0.0 1.3e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EEQ37109.1 - 8.2e-09 35.4 0.2 1.3e-08 34.7 0.2 1.4 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 EEQ37109.1 - 1.2e-05 26.1 0.0 2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain ADK PF00406.22 EEQ37110.1 - 4.9e-44 150.1 0.0 6.3e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EEQ37110.1 - 1.2e-34 119.7 0.0 1.6e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ37110.1 - 4.5e-08 33.7 0.0 6.5e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ37110.1 - 2.4e-06 27.8 0.0 6.1e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 EEQ37110.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EEQ37110.1 - 0.093 12.0 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin adh_short PF00106.25 EEQ37111.1 - 2.2e-44 151.3 0.3 2.7e-44 151.0 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ37111.1 - 1.7e-29 103.1 0.2 1.8e-29 102.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ37111.1 - 9.4e-11 41.9 0.4 1.3e-10 41.5 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EEQ37111.1 - 5e-08 33.1 0.4 7.1e-08 32.5 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ37111.1 - 0.0087 15.6 0.3 0.011 15.3 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EEQ37111.1 - 0.0097 16.2 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.12 EEQ37111.1 - 0.056 12.6 0.2 0.11 11.6 0.2 1.8 1 1 0 1 1 1 0 Male sterility protein Pan3_PK PF18101.1 EEQ37112.1 - 3.2e-40 137.3 2.2 5.3e-40 136.6 2.2 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EEQ37112.1 - 0.0059 16.0 0.0 0.0098 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-CCCH PF00642.24 EEQ37112.1 - 0.046 13.7 0.5 0.087 12.8 0.5 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2290 PF10053.9 EEQ37113.1 - 0.0014 18.1 0.1 0.0018 17.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2290) Cyclin_N PF00134.23 EEQ37113.1 - 0.053 13.3 0.1 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Cyclin, N-terminal domain GET2 PF08690.10 EEQ37113.1 - 0.09 12.4 0.2 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 NAP PF00956.18 EEQ37114.1 - 1.8e-97 325.8 13.3 2.8e-97 325.1 13.3 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) ABC_membrane_2 PF06472.15 EEQ37115.1 - 1.7e-89 299.8 5.3 2.7e-89 299.2 5.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EEQ37115.1 - 3.3e-18 66.5 0.0 1.4e-17 64.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_23 PF13476.6 EEQ37115.1 - 0.00089 19.8 5.1 0.0013 19.3 1.0 2.8 2 2 0 2 2 2 1 AAA domain SMC_N PF02463.19 EEQ37115.1 - 0.015 14.8 0.1 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EEQ37115.1 - 0.037 14.0 0.1 0.38 10.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EEQ37115.1 - 0.038 13.7 0.0 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EEQ37115.1 - 0.1 12.0 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 EEQ37115.1 - 0.11 13.0 0.0 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EEQ37115.1 - 0.13 12.0 4.3 0.59 9.9 2.0 2.8 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Mito_carr PF00153.27 EEQ37116.1 - 4.4e-55 183.6 2.8 5.2e-18 64.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4336 PF14234.6 EEQ37117.1 - 5.4e-07 29.1 0.0 0.00026 20.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) EutB PF06751.11 EEQ37117.1 - 0.048 12.5 0.0 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) M16C_assoc PF08367.11 EEQ37118.1 - 6.1e-70 235.2 0.8 1.1e-69 234.4 0.9 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EEQ37118.1 - 3.2e-18 66.4 2.7 1.5e-14 54.4 0.1 3.8 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEQ37118.1 - 1.5e-06 28.2 1.8 5.7e-06 26.4 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) HIM1 PF08732.10 EEQ37118.1 - 0.052 13.1 0.2 0.22 11.0 0.1 2.0 2 0 0 2 2 2 0 HIM1 Ribosomal_L33 PF00471.20 EEQ37119.1 - 0.00017 22.0 1.1 0.00021 21.6 0.7 1.5 1 1 0 1 1 1 1 Ribosomal protein L33 EMP24_GP25L PF01105.24 EEQ37120.1 - 1.9e-40 138.8 0.4 2.4e-40 138.4 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Rad33 PF08730.10 EEQ37122.1 - 6.1e-54 182.4 0.0 7.6e-54 182.1 0.0 1.1 1 0 0 1 1 1 1 Rad33 PALP PF00291.25 EEQ37123.1 - 4.3e-53 180.6 0.0 5.1e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DOT1 PF08123.13 EEQ37125.1 - 9.6e-73 244.1 0.0 2e-72 243.1 0.0 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 SLIDE PF09111.10 EEQ37126.1 - 1.5e-38 131.3 2.2 2.3e-38 130.7 0.6 2.2 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EEQ37126.1 - 6.1e-33 113.9 5.7 2e-32 112.2 5.7 1.9 1 0 0 1 1 1 1 HAND Helicase_C PF00271.31 EEQ37126.1 - 8.7e-10 38.9 0.8 2.3e-09 37.5 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HTH_24 PF13412.6 EEQ37126.1 - 0.057 13.0 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding SNF2_N PF00176.23 EEQ37127.1 - 1.3e-75 254.3 0.4 2.3e-75 253.5 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EEQ37127.1 - 2.2e-13 50.6 0.3 1.5e-12 47.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ37127.1 - 1.1e-06 28.9 0.0 7.5e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EEQ37127.1 - 1.2e-05 25.1 0.9 2e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 SWI2/SNF2 ATPase DEAD PF00270.29 EEQ37127.1 - 1.5e-05 24.8 0.0 4.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EEQ37127.1 - 0.03 13.6 0.3 0.072 12.3 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UDG PF03167.19 EEQ37128.1 - 8.2e-18 64.9 0.1 1.9e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MAGUK_N_PEST PF10608.9 EEQ37128.1 - 0.034 14.6 2.9 0.034 14.6 2.9 2.5 3 0 0 3 3 3 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Mannitol_dh PF01232.23 EEQ37128.1 - 0.18 11.9 1.2 0.39 10.9 1.2 1.5 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain OST3_OST6 PF04756.13 EEQ37129.1 - 2.4e-60 204.4 0.6 3.3e-60 203.9 0.6 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EEQ37129.1 - 0.026 14.7 0.0 0.082 13.1 0.0 1.8 1 1 0 1 1 1 0 Glutaredoxin EamA PF00892.20 EEQ37130.1 - 4.7e-14 52.7 33.3 6.8e-08 32.8 13.7 3.2 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EEQ37130.1 - 2.1e-05 23.9 5.3 2.1e-05 23.9 5.3 2.2 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 EEQ37130.1 - 0.0042 16.9 0.3 0.0042 16.9 0.3 4.4 5 0 0 5 5 5 2 Protein of unknown function (DUF3955) TPT PF03151.16 EEQ37130.1 - 0.027 13.8 19.8 0.0048 16.3 14.2 2.2 2 1 0 2 2 2 0 Triose-phosphate Transporter family SLC35F PF06027.12 EEQ37130.1 - 0.055 13.0 19.1 0.01 15.4 15.6 1.5 2 0 0 2 2 2 0 Solute carrier family 35 Aa_trans PF01490.18 EEQ37131.1 - 2.8e-58 197.6 31.5 3.3e-58 197.4 31.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Med14 PF08638.11 EEQ37132.1 - 1.2e-57 194.4 0.3 1.2e-57 194.4 0.3 2.8 3 0 0 3 3 3 1 Mediator complex subunit MED14 PolyA_pol_RNAbd PF12627.7 EEQ37132.1 - 0.67 9.8 2.5 4 7.3 0.1 3.0 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A Pkinase PF00069.25 EEQ37133.1 - 9e-37 126.9 0.0 1.5e-36 126.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37133.1 - 3.7e-20 72.3 0.0 3e-13 49.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ37133.1 - 0.0035 16.7 0.1 2.9 7.1 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EEQ37133.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Efg1 PF10153.9 EEQ37134.1 - 0.12 12.7 5.3 0.35 11.3 5.3 1.7 1 0 0 1 1 1 0 rRNA-processing protein Efg1 WD40 PF00400.32 EEQ37136.1 - 4.1e-11 43.3 0.9 0.0019 19.0 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat TFIIIC_delta PF12657.7 EEQ37136.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term SET PF00856.28 EEQ37137.1 - 1.2e-15 58.3 0.0 2e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 SET domain Sporozoite_P67 PF05642.11 EEQ37137.1 - 0.016 13.4 0.5 0.021 12.9 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.11 EEQ37137.1 - 0.027 14.5 0.6 0.055 13.5 0.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal Peptidase_C36 PF05415.11 EEQ37137.1 - 0.15 12.3 0.1 0.41 10.9 0.1 1.7 1 0 0 1 1 1 0 Beet necrotic yellow vein furovirus-type papain-like endopeptidase CENP-B_dimeris PF09026.10 EEQ37137.1 - 0.15 12.4 9.5 0.35 11.3 9.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EEQ37137.1 - 0.27 10.5 4.1 0.48 9.7 4.1 1.4 1 0 0 1 1 1 0 NOA36 protein TRP PF06011.12 EEQ37138.1 - 1.3e-60 205.3 21.7 2.8e-48 164.7 17.2 2.1 1 1 1 2 2 2 2 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EEQ37138.1 - 0.00088 19.7 0.1 0.0023 18.3 0.1 1.6 1 0 0 1 1 1 1 ML-like domain PRD PF00874.20 EEQ37138.1 - 0.31 11.4 4.8 0.3 11.4 0.5 3.0 2 1 0 2 2 2 0 PRD domain Cyclin_N PF00134.23 EEQ37140.1 - 8.8e-21 74.0 0.1 2.9e-20 72.3 0.1 2.0 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EEQ37140.1 - 1e-10 42.2 0.2 1e-10 42.2 0.2 2.1 2 0 0 2 2 2 1 Cyclin Fungal_trans PF04082.18 EEQ37141.1 - 5.7e-11 41.9 1.2 1.1e-10 41.0 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ37141.1 - 2.5e-06 27.5 9.5 6.6e-06 26.2 9.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TIMELESS PF04821.14 EEQ37142.1 - 1e-79 267.7 0.2 1.4e-77 260.7 0.0 2.6 2 0 0 2 2 2 2 Timeless protein Aa_trans PF01490.18 EEQ37143.1 - 1.2e-73 248.2 27.6 1.5e-73 247.9 27.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EEQ37143.1 - 1.2e-05 24.6 15.2 1.2e-05 24.6 15.2 1.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF485 PF04341.12 EEQ37143.1 - 0.32 11.0 0.0 0.32 11.0 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function, DUF485 rRNA_processing PF08524.11 EEQ37144.1 - 6.2e-40 136.6 25.2 9.1e-40 136.1 25.2 1.2 1 0 0 1 1 1 1 rRNA processing XRCC4 PF06632.12 EEQ37144.1 - 0.013 14.4 16.1 0.017 14.0 16.1 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 CDC45 PF02724.14 EEQ37144.1 - 0.11 10.8 14.8 0.15 10.4 14.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.7 EEQ37144.1 - 0.32 10.8 10.6 0.39 10.5 10.6 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein eIF-3c_N PF05470.12 EEQ37144.1 - 0.69 8.1 11.7 0.8 7.9 11.7 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CENP-B_dimeris PF09026.10 EEQ37144.1 - 2.1 8.8 6.6 4.1 7.9 6.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Presenilin PF01080.17 EEQ37144.1 - 3.6 6.3 13.0 4.7 5.9 13.0 1.1 1 0 0 1 1 1 0 Presenilin D123 PF07065.14 EEQ37144.1 - 6.1 5.9 12.9 0.34 10.0 3.5 2.0 1 1 0 2 2 2 0 D123 ABC1 PF03109.16 EEQ37145.1 - 1.7e-32 112.1 0.1 3.5e-32 111.1 0.1 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EEQ37145.1 - 0.0057 16.3 0.0 0.026 14.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family PRANC PF09372.10 EEQ37145.1 - 0.045 14.1 0.1 0.15 12.4 0.1 1.9 1 0 0 1 1 1 0 PRANC domain Zn_clus PF00172.18 EEQ37146.1 - 9.9e-08 32.0 10.1 9.9e-08 32.0 10.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 EEQ37147.1 - 4.9e-13 48.6 0.5 5.8e-13 48.3 0.5 1.1 1 0 0 1 1 1 1 LSM domain Pyr_redox_2 PF07992.14 EEQ37148.1 - 3.9e-59 200.3 2.4 6.1e-59 199.7 2.1 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EEQ37148.1 - 2.2e-31 108.4 0.0 7.6e-31 106.6 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EEQ37148.1 - 1.4e-16 60.8 7.8 5.5e-15 55.7 1.3 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEQ37148.1 - 2.4e-07 30.5 0.6 4.1e-07 29.7 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EEQ37148.1 - 7.4e-07 28.7 3.6 8.7e-05 21.9 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ37148.1 - 4.3e-05 22.4 2.4 0.0072 15.1 0.3 3.0 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 EEQ37148.1 - 5.8e-05 22.3 0.3 5.8e-05 22.3 0.3 2.6 2 1 1 3 3 3 1 Glucose inhibited division protein A K_oxygenase PF13434.6 EEQ37148.1 - 0.00044 19.5 0.0 0.00075 18.7 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EEQ37148.1 - 0.00088 18.6 5.4 0.15 11.3 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EEQ37148.1 - 0.0016 17.9 1.1 0.17 11.2 0.0 2.7 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EEQ37148.1 - 0.0017 17.5 1.0 0.0085 15.2 2.0 1.6 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.18 EEQ37148.1 - 0.015 15.2 5.0 0.076 12.9 0.3 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 EEQ37148.1 - 0.027 14.7 3.1 0.081 13.2 3.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EEQ37148.1 - 0.029 14.8 1.1 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.24 EEQ37148.1 - 0.042 13.4 0.1 0.042 13.4 0.1 1.8 2 0 0 2 2 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 EEQ37148.1 - 0.053 12.8 0.3 0.16 11.2 0.2 1.9 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.19 EEQ37148.1 - 0.056 12.7 2.8 1.5 8.0 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain NAPRTase_C PF17956.1 EEQ37148.1 - 0.14 12.6 0.0 0.45 11.0 0.0 1.9 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase C-terminal domain NAD_binding_9 PF13454.6 EEQ37148.1 - 0.29 11.1 2.0 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding ANAPC9 PF12856.7 EEQ37149.1 - 3.2e-39 133.8 0.8 3.2e-39 133.8 0.8 2.0 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 9 V-set PF07686.17 EEQ37149.1 - 0.16 12.2 0.8 7.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Immunoglobulin V-set domain Glutaredoxin PF00462.24 EEQ37150.1 - 1.8e-12 47.3 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin FANCI_S1-cap PF14674.6 EEQ37150.1 - 0.045 13.8 0.1 0.65 10.1 0.0 2.3 2 0 0 2 2 2 0 FANCI solenoid 1 cap Thioredoxin_2 PF13098.6 EEQ37150.1 - 0.058 13.9 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain PIN_9 PF18477.1 EEQ37150.1 - 0.16 12.2 0.0 0.41 11.0 0.0 1.7 2 0 0 2 2 2 0 PIN like domain MFS_1 PF07690.16 EEQ37151.1 - 5.2e-34 117.7 26.5 8.1e-34 117.1 26.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ37151.1 - 2.6e-28 99.1 26.3 1.7e-26 93.1 26.3 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MASE4 PF17158.4 EEQ37151.1 - 0.011 15.0 0.7 0.011 15.0 0.7 2.1 2 0 0 2 2 2 0 Membrane-associated sensor, integral membrane domain Abhydrolase_9_N PF15420.6 EEQ37151.1 - 0.083 12.9 0.7 0.42 10.6 0.1 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Malate_synthase PF01274.22 EEQ37152.1 - 3.2e-226 751.7 0.0 3.6e-226 751.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase CMAS PF02353.20 EEQ37153.1 - 2.9e-58 197.3 0.3 3.5e-58 197.0 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EEQ37153.1 - 2.4e-10 40.5 0.0 4.5e-10 39.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ37153.1 - 1.1e-09 38.9 0.0 1.9e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ37153.1 - 9.3e-08 32.6 0.0 1.9e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ37153.1 - 6e-05 22.9 0.0 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ37153.1 - 0.00011 22.9 0.0 0.00019 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EEQ37153.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 COX7C PF02935.16 EEQ37153.1 - 0.0074 16.5 4.2 0.027 14.7 4.2 2.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc MTS PF05175.14 EEQ37153.1 - 0.054 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 EEQ37153.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase SIR2 PF02146.17 EEQ37154.1 - 2.9e-61 206.5 0.0 4.3e-61 205.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 EEQ37154.1 - 7.4e-28 97.3 3.3 7.1e-25 87.6 3.3 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 EEQ37154.1 - 5.3e-05 23.0 0.0 0.029 14.1 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain HLH PF00010.26 EEQ37156.1 - 6.1e-16 58.1 0.0 1.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Dehydrin PF00257.19 EEQ37156.1 - 0.045 14.3 1.7 0.074 13.6 1.7 1.3 1 0 0 1 1 1 0 Dehydrin PAPS_reduct PF01507.19 EEQ37157.1 - 5.2e-20 72.2 0.2 8.1e-17 61.8 0.0 2.1 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Epimerase PF01370.21 EEQ37158.1 - 3.8e-14 52.8 0.1 8.3e-14 51.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ37158.1 - 1.1e-12 47.5 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEQ37158.1 - 1.7e-06 27.6 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EEQ37158.1 - 3.3e-06 27.1 0.0 7.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EEQ37158.1 - 1.5e-05 24.3 0.1 0.0034 16.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EEQ37158.1 - 0.00017 21.1 0.0 0.00044 19.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EEQ37158.1 - 0.001 18.7 0.2 0.064 12.8 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 EEQ37158.1 - 0.024 14.5 0.4 0.29 11.0 0.2 2.5 2 1 0 2 2 2 0 KR domain FMN_red PF03358.15 EEQ37159.1 - 2.3e-07 30.7 0.1 6.7e-07 29.2 0.1 1.8 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 EEQ37159.1 - 7.6e-07 29.4 0.1 8.4e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EEQ37159.1 - 9.9e-06 25.8 0.0 1.5e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin domain Flavodoxin_2 PF02525.17 EEQ37159.1 - 0.03 14.0 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Flavodoxin_3 PF12641.7 EEQ37159.1 - 0.032 13.9 0.1 0.045 13.4 0.1 1.2 1 0 0 1 1 1 0 Flavodoxin domain SF3A2 PF16835.5 EEQ37160.1 - 3.9e-30 104.1 4.8 2.6e-29 101.4 4.8 2.0 1 1 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EEQ37160.1 - 7.5e-08 32.5 0.8 2.2e-07 31.0 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Ank_2 PF12796.7 EEQ37161.1 - 6.3e-06 26.7 0.1 0.18 12.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ37161.1 - 1.9e-05 24.9 0.1 0.43 11.1 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat KilA-N PF04383.13 EEQ37161.1 - 0.00076 19.3 0.0 0.0042 16.9 0.0 2.3 2 0 0 2 2 2 1 KilA-N domain Ank_4 PF13637.6 EEQ37161.1 - 0.00088 19.8 0.1 2.1 9.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ37161.1 - 0.082 13.5 0.1 85 4.2 0.0 4.0 4 0 0 4 4 4 0 Ankyrin repeat NYD-SP28 PF14772.6 EEQ37161.1 - 0.16 12.0 4.0 0.13 12.3 1.6 2.1 2 0 0 2 2 2 0 Sperm tail EF-hand_7 PF13499.6 EEQ37162.1 - 2e-14 53.8 5.8 2.4e-06 27.9 0.4 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EEQ37162.1 - 1.2e-12 46.6 7.9 1.7e-05 24.4 0.1 4.9 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 EEQ37162.1 - 1.3e-12 46.3 4.7 1.3e-05 24.4 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EEQ37162.1 - 2.5e-09 36.8 7.2 1e-05 25.3 1.3 3.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EEQ37162.1 - 0.00011 21.6 8.5 0.62 9.7 0.0 4.5 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 EEQ37162.1 - 0.00035 20.5 0.9 0.26 11.2 0.0 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EEQ37162.1 - 0.16 12.3 2.3 0.58 10.5 0.6 2.6 2 1 1 3 3 3 0 EF-hand domain Sdh5 PF03937.16 EEQ37163.1 - 9.2e-29 99.2 0.4 1.4e-28 98.7 0.4 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase TFIIE_alpha PF02002.17 EEQ37163.1 - 0.1 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit Vta1 PF04652.16 EEQ37164.1 - 2.2e-35 121.7 0.3 2.2e-35 121.7 0.3 1.7 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EEQ37164.1 - 1.3e-15 56.8 0.6 2.8e-15 55.7 0.6 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain zf-DBF PF07535.12 EEQ37164.1 - 0.032 14.3 0.1 0.061 13.4 0.1 1.5 1 0 0 1 1 1 0 DBF zinc finger La PF05383.17 EEQ37165.1 - 1.2e-10 41.3 0.0 1.9e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 La domain Slu7 PF11708.8 EEQ37166.1 - 1.7e-21 77.2 22.8 7.4e-19 68.5 22.8 2.2 1 1 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor Nop52 PF05997.12 EEQ37167.1 - 1.8e-74 250.2 5.7 2.5e-74 249.7 5.7 1.2 1 0 0 1 1 1 1 Nucleolar protein,Nop52 BSP_II PF05432.11 EEQ37167.1 - 0.004 16.9 17.7 0.0055 16.4 17.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CFIA_Pcf11 PF11526.8 EEQ37167.1 - 0.013 15.9 8.3 0.026 15.0 8.3 1.6 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Sporozoite_P67 PF05642.11 EEQ37167.1 - 0.24 9.5 6.9 0.3 9.1 6.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 EEQ37167.1 - 7.3 4.7 13.1 10 4.2 13.1 1.2 1 0 0 1 1 1 0 CDC45-like protein ATP13 PF12921.7 EEQ37168.1 - 9.7e-29 99.6 0.5 3.1e-28 97.9 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial ATPase expression ECH_1 PF00378.20 EEQ37169.1 - 5.7e-28 97.9 0.0 9e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EEQ37169.1 - 3.2e-25 89.4 0.0 3.7e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ribosomal_S18 PF01084.20 EEQ37169.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S18 DEAD PF00270.29 EEQ37170.1 - 1.1e-48 165.3 0.0 2.5e-48 164.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ37170.1 - 1.1e-24 86.8 0.0 1.4e-23 83.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SLC12 PF03522.15 EEQ37171.1 - 5.9e-05 22.3 8.8 0.0045 16.1 0.1 3.1 3 1 0 3 3 3 2 Solute carrier family 12 Spc42p PF11544.8 EEQ37171.1 - 0.3 11.1 1.9 0.48 10.5 0.3 2.2 2 0 0 2 2 2 0 Spindle pole body component Spc42p DUF4252 PF14060.6 EEQ37171.1 - 1.1 9.1 5.3 24 4.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4252) AA_permease PF00324.21 EEQ37172.1 - 1.1e-25 90.2 13.0 1.3e-25 90.0 13.0 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EEQ37172.1 - 0.012 14.7 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DHHA2 PF02833.14 EEQ37172.1 - 0.16 12.1 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 DHHA2 domain AA_permease PF00324.21 EEQ37173.1 - 2.7e-22 79.0 14.7 3.2e-22 78.8 14.7 1.0 1 0 0 1 1 1 1 Amino acid permease TMEM220 PF15071.6 EEQ37173.1 - 0.087 13.6 2.4 0.1 13.4 0.7 1.9 2 0 0 2 2 2 0 Transmembrane family 220, helix DUF240 PF03086.14 EEQ37174.1 - 0.0067 16.3 1.2 0.037 13.9 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF240) ORC4_C PF14629.6 EEQ37174.1 - 0.032 13.6 1.4 0.62 9.4 0.0 3.0 3 0 0 3 3 3 0 Origin recognition complex (ORC) subunit 4 C-terminus Hydin_ADK PF17213.3 EEQ37174.1 - 0.17 12.2 0.0 0.27 11.5 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain ANAPC5 PF12862.7 EEQ37174.1 - 0.4 10.8 9.7 9.8 6.3 1.8 4.0 3 2 0 3 3 3 0 Anaphase-promoting complex subunit 5 TAF6_C PF07571.13 EEQ37175.1 - 5.8e-28 97.1 0.4 1.4e-27 95.8 0.1 1.9 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EEQ37175.1 - 6.9e-27 93.4 0.3 2.7e-26 91.5 0.0 2.2 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EEQ37175.1 - 0.00025 21.4 0.7 0.0033 17.8 0.1 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEQ37175.1 - 0.0055 17.0 0.3 0.031 14.5 0.1 2.3 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SLD3 PF08639.10 EEQ37176.1 - 1.2e-27 97.0 17.2 2.1e-27 96.1 4.5 2.5 1 1 1 2 2 2 2 DNA replication regulator SLD3 Pkinase PF00069.25 EEQ37177.1 - 2.5e-56 191.0 0.1 5.6e-56 189.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37177.1 - 3.1e-21 75.8 0.0 4.9e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ37177.1 - 2.3e-05 23.9 0.0 4.3e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAS PF00989.25 EEQ37177.1 - 0.0019 18.2 0.0 4 7.5 0.0 2.9 2 1 0 2 2 2 2 PAS fold Kdo PF06293.14 EEQ37177.1 - 0.0021 17.5 0.1 0.0047 16.3 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 EEQ37177.1 - 0.0023 18.2 0.0 0.3 11.4 0.0 3.5 3 0 0 3 3 3 1 PAS domain Pkinase_fungal PF17667.1 EEQ37177.1 - 0.0044 15.9 0.5 0.015 14.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EEQ37177.1 - 0.013 15.1 0.2 0.044 13.4 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEQ37177.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS_8 PF13188.7 EEQ37177.1 - 0.017 15.1 0.0 2.4 8.3 0.0 3.0 3 0 0 3 3 3 0 PAS domain LDB19 PF13002.7 EEQ37178.1 - 2.3e-61 206.9 0.1 3.7e-61 206.2 0.1 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Creatininase PF02633.14 EEQ37178.1 - 0.011 15.3 0.2 0.022 14.2 0.2 1.5 1 0 0 1 1 1 0 Creatinine amidohydrolase Arrestin_N PF00339.29 EEQ37178.1 - 0.031 14.3 0.0 0.08 13.0 0.0 1.7 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Actin PF00022.19 EEQ37179.1 - 2e-68 230.9 0.0 2.9e-67 227.1 0.0 2.0 1 1 0 1 1 1 1 Actin PIG-L PF02585.17 EEQ37180.1 - 2.5e-24 86.4 0.1 3.4e-24 86.0 0.1 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Methyltransf_11 PF08241.12 EEQ37181.1 - 1.6e-20 73.6 0.0 2.8e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ37181.1 - 1.9e-19 70.2 0.0 3.5e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ37181.1 - 2.4e-18 66.4 0.0 3.6e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ37181.1 - 3.9e-18 66.0 0.0 6.4e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ37181.1 - 8.3e-15 55.0 0.0 1.2e-14 54.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ37181.1 - 1.2e-11 44.5 0.0 1.8e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 EEQ37181.1 - 3.2e-09 35.9 0.0 4.3e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 EEQ37181.1 - 1.9e-06 27.7 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 EEQ37181.1 - 2.5e-05 23.7 0.0 6.8e-05 22.3 0.0 1.6 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EEQ37181.1 - 3.5e-05 23.4 0.0 6.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EEQ37181.1 - 0.0075 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEQ37181.1 - 0.0085 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Fungal_trans PF04082.18 EEQ37182.1 - 1.2e-32 113.0 1.9 2.3e-32 112.1 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ37182.1 - 2.4e-10 40.4 9.1 4.5e-10 39.5 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 EEQ37182.1 - 0.028 14.5 0.1 0.13 12.4 0.1 2.1 1 0 0 1 1 1 0 bZIP transcription factor HhH-GPD PF00730.25 EEQ37183.1 - 3.7e-17 62.7 0.0 6.7e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EEQ37183.1 - 0.034 14.0 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Exo_endo_phos PF03372.23 EEQ37184.1 - 1.3e-16 60.9 0.1 1.7e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EEQ37184.1 - 0.019 14.8 0.1 0.16 11.8 0.0 2.4 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.23 EEQ37185.1 - 1.6e-24 86.7 0.0 4.9e-24 85.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 EEQ37185.1 - 3.9e-15 55.3 13.4 2.5e-09 36.8 2.1 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EEQ37185.1 - 7.5e-13 48.5 9.8 6.3e-08 32.8 0.4 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EEQ37185.1 - 0.0048 17.3 13.8 14 6.7 0.6 5.3 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_9 PF14580.6 EEQ37185.1 - 0.024 14.1 0.9 0.074 12.5 0.9 1.8 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 EEQ37185.1 - 0.046 13.8 4.6 2 8.7 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Exo_endo_phos_2 PF14529.6 EEQ37185.1 - 0.071 13.0 0.3 2.4 8.0 0.3 3.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase His_Phos_1 PF00300.22 EEQ37186.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Sugar_tr PF00083.24 EEQ37187.1 - 2e-33 116.0 32.4 1.8e-20 73.2 9.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EEQ37187.1 - 1.2e-20 73.8 37.1 2.8e-12 46.2 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.14 EEQ37188.1 - 2.4e-07 30.8 0.0 5.5e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EEQ37188.1 - 8.9e-05 22.0 0.1 0.0004 19.8 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family DIM1 PF02966.16 EEQ37190.1 - 1.2e-69 232.2 0.4 1.4e-69 232.0 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EEQ37190.1 - 0.0077 16.2 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.8 EEQ37190.1 - 0.17 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) PBP PF01161.20 EEQ37191.1 - 7.4e-24 84.5 0.0 9.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CBFD_NFYB_HMF PF00808.23 EEQ37192.1 - 1.1e-19 70.4 0.6 2e-19 69.6 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ37192.1 - 1.6e-16 60.9 1.9 1.7e-16 60.8 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EEQ37192.1 - 0.02 15.2 0.1 0.042 14.2 0.1 1.5 1 0 0 1 1 1 0 CENP-S associating Centromere protein X SPOB_a PF14689.6 EEQ37192.1 - 0.16 11.7 2.3 0.37 10.5 2.3 1.6 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain PMT PF02366.18 EEQ37193.1 - 1.1e-77 260.9 18.5 2.4e-77 259.9 18.5 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EEQ37193.1 - 9.7e-53 178.7 16.3 9.7e-53 178.7 16.3 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EEQ37193.1 - 1.5e-23 83.7 0.1 2.7e-23 82.8 0.1 1.3 1 0 0 1 1 1 1 MIR domain PhzC-PhzF PF02567.16 EEQ37194.1 - 6e-56 190.0 0.0 6.8e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 EEQ37194.1 - 1.6e-08 34.0 0.0 2.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Proline racemase DUF3533 PF12051.8 EEQ37195.1 - 2.5e-129 431.5 23.5 3e-129 431.2 23.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Serglycin PF04360.12 EEQ37195.1 - 0.15 12.0 3.2 0.19 11.6 1.6 2.0 2 0 0 2 2 2 0 Serglycin Herpes_gE PF02480.16 EEQ37195.1 - 0.45 9.2 2.5 4.1 6.1 0.3 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E ABC2_membrane_3 PF12698.7 EEQ37195.1 - 1.6 7.7 38.0 4.9 6.2 0.1 2.6 2 1 0 2 2 2 0 ABC-2 family transporter protein Mcp5_PH PF12814.7 EEQ37196.1 - 1.4e-43 147.8 0.6 5.8e-43 145.9 0.6 2.2 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EEQ37196.1 - 5.5e-05 23.6 0.1 0.00028 21.4 0.1 2.4 1 0 0 1 1 1 1 PH domain DUF5615 PF18480.1 EEQ37196.1 - 0.0047 16.7 0.1 3.4 7.5 0.0 5.2 4 0 0 4 4 4 1 Domain of unknown function (DUF5615) UPF0180 PF03698.13 EEQ37196.1 - 0.013 15.6 0.4 6.1 7.1 0.0 5.1 5 0 0 5 5 5 0 Uncharacterised protein family (UPF0180) PH_2 PF08458.10 EEQ37196.1 - 0.07 13.5 0.1 40 4.6 0.1 3.6 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_12 PF16457.5 EEQ37196.1 - 0.092 13.3 6.3 1.7 9.2 0.0 5.8 3 2 0 3 3 3 0 Pleckstrin homology domain GidB PF02527.15 EEQ37196.1 - 0.19 11.0 2.8 0.8 9.0 0.2 3.3 3 0 0 3 3 3 0 rRNA small subunit methyltransferase G PhdYeFM_antitox PF02604.19 EEQ37196.1 - 3.1 7.7 23.6 14 5.5 0.2 11.5 14 1 0 14 14 14 0 Antitoxin Phd_YefM, type II toxin-antitoxin system DUF3450 PF11932.8 EEQ37196.1 - 3.5 6.9 17.9 5 6.4 9.9 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) EF-hand_1 PF00036.32 EEQ37197.1 - 8.3e-28 93.8 4.4 1.4e-08 33.7 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EEQ37197.1 - 3e-25 87.8 3.2 8.5e-11 41.5 0.1 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 EEQ37197.1 - 1.1e-24 86.7 1.0 6.8e-16 58.5 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EEQ37197.1 - 2.6e-21 74.1 4.1 5e-08 32.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EEQ37197.1 - 1.6e-17 61.9 3.0 1.8e-08 33.6 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_9 PF14658.6 EEQ37197.1 - 6.2e-09 36.0 0.2 0.00039 20.7 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 EEQ37197.1 - 6e-07 29.6 5.2 0.00038 20.6 1.0 3.0 1 1 2 3 3 3 3 Dockerin type I domain EF-hand_4 PF12763.7 EEQ37197.1 - 7.4e-07 29.1 1.6 0.0086 16.0 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EEQ37197.1 - 1.1e-06 28.9 0.1 0.0001 22.6 0.0 2.1 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EEQ37197.1 - 1.2e-05 25.3 0.0 0.19 11.8 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 EEQ37197.1 - 0.00096 20.0 0.0 0.11 13.4 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EEQ37197.1 - 0.0011 18.9 0.3 0.013 15.4 0.1 2.0 1 1 0 2 2 2 1 Tellurite resistance protein TerB EF-hand_10 PF14788.6 EEQ37197.1 - 0.0094 15.8 0.5 0.023 14.5 0.0 1.9 2 1 0 2 2 2 1 EF hand Poly_export PF02563.16 EEQ37197.1 - 0.01 16.1 0.0 0.034 14.4 0.0 1.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis/export protein DUF5580 PF17743.1 EEQ37197.1 - 0.11 11.0 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) VCBS PF13517.6 EEQ37197.1 - 0.71 10.5 3.6 5.5 7.7 3.6 2.3 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella IMS PF00817.20 EEQ37198.1 - 2.3e-35 121.8 0.0 7.8e-35 120.1 0.0 2.0 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EEQ37198.1 - 2.7e-13 50.6 0.0 1.3e-12 48.4 0.0 2.1 1 1 1 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EEQ37198.1 - 9.6e-12 45.2 0.0 3.8e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EEQ37198.1 - 2.5e-05 24.6 0.0 8.4e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain REV1_C PF16727.5 EEQ37198.1 - 2.5e-05 24.6 0.0 5.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain LIG3_BRCT PF16759.5 EEQ37198.1 - 4e-05 23.8 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 EEQ37198.1 - 5.6e-05 23.2 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Hist_deacetyl PF00850.19 EEQ37199.1 - 2.4e-74 250.6 0.0 2.9e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Glycos_transf_1 PF00534.20 EEQ37200.1 - 8.9e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ37200.1 - 2e-11 44.5 0.0 5.3e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EEQ37200.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEQ37200.1 - 0.018 15.0 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 zf-CCCH PF00642.24 EEQ37201.1 - 3.6e-10 39.5 1.9 8.2e-10 38.4 1.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_UBOX PF13445.6 EEQ37201.1 - 1.9e-08 34.2 10.8 4.9e-08 32.9 10.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEQ37201.1 - 1.3e-07 31.3 10.7 1.3e-07 31.3 10.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ37201.1 - 1.5e-07 31.2 7.6 4e-07 29.8 7.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ37201.1 - 2.4e-07 30.6 12.0 6.1e-07 29.3 12.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EEQ37201.1 - 2.5e-07 30.4 12.8 5.6e-07 29.3 12.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ37201.1 - 3.7e-07 30.4 10.0 8.9e-07 29.1 10.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 EEQ37201.1 - 8e-07 28.9 4.9 2.1e-06 27.6 4.9 1.8 1 0 0 1 1 1 1 Zinc finger domain zf-C3HC4_4 PF15227.6 EEQ37201.1 - 1.9e-06 27.9 9.7 3.8e-06 27.0 9.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EEQ37201.1 - 0.00031 20.5 9.2 0.0016 18.3 9.3 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-CCCH_4 PF18044.1 EEQ37201.1 - 0.00091 19.0 1.6 0.00091 19.0 1.6 2.0 3 0 0 3 3 2 1 CCCH-type zinc finger zf-Nse PF11789.8 EEQ37201.1 - 0.01 15.6 7.2 0.021 14.6 7.2 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EEQ37201.1 - 0.11 12.3 11.3 3.1 7.7 0.1 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EEQ37201.1 - 0.17 11.8 2.2 0.3 11.0 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EEQ37201.1 - 0.41 11.0 8.8 1.9 8.8 8.9 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-HC5HC2H PF13771.6 EEQ37201.1 - 1 9.7 9.4 0.92 9.8 0.4 2.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-RING_10 PF16685.5 EEQ37201.1 - 4.5 7.5 13.6 0.17 12.0 6.5 2.3 3 0 0 3 3 3 0 zinc RING finger of MSL2 CTP_transf_like PF01467.26 EEQ37202.1 - 3.3e-28 98.7 0.0 2.1e-17 63.6 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EEQ37202.1 - 0.00028 20.8 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 2 FAD synthetase baeRF_family10 PF18854.1 EEQ37202.1 - 0.061 13.6 0.0 2.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 HABP4_PAI-RBP1 PF04774.15 EEQ37203.1 - 0.011 16.6 1.5 0.013 16.3 1.5 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family IBR PF01485.21 EEQ37204.1 - 1.5e-15 57.1 38.8 3.4e-09 36.8 5.0 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EEQ37204.1 - 6.9e-15 55.4 1.2 1e-14 54.8 0.2 1.8 2 0 0 2 2 2 1 RWD domain zf-RING_2 PF13639.6 EEQ37204.1 - 0.0001 22.6 8.4 0.0001 22.6 8.4 4.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ37204.1 - 0.00031 20.6 8.0 0.00031 20.6 8.0 4.3 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ37204.1 - 0.00046 20.2 8.3 0.00046 20.2 8.3 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ37204.1 - 0.0013 18.6 9.1 0.0013 18.6 9.1 4.4 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EEQ37204.1 - 0.003 17.4 6.0 0.003 17.4 6.0 4.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ37204.1 - 0.36 10.6 8.0 1.1 9.0 8.0 2.0 1 0 0 1 1 1 0 RING-like zinc finger CN_hydrolase PF00795.22 EEQ37205.1 - 4.2e-21 75.5 0.0 5.9e-19 68.4 0.0 2.9 3 0 0 3 3 3 3 Carbon-nitrogen hydrolase Rav1p_C PF12234.8 EEQ37206.1 - 7.4e-233 774.6 3.4 1.2e-232 773.9 0.2 2.5 3 0 0 3 3 3 1 RAVE protein 1 C terminal Cas9_a PF18470.1 EEQ37206.1 - 0.0012 18.4 0.1 0.0027 17.3 0.1 1.5 1 0 0 1 1 1 1 Cas9 alpha-helical lobe domain Lipoprotein_17 PF04200.12 EEQ37206.1 - 0.042 14.2 5.5 3.7 8.0 0.2 3.5 3 0 0 3 3 3 0 Lipoprotein associated domain MFS_1 PF07690.16 EEQ37207.1 - 2.9e-08 33.0 53.0 6.9e-07 28.5 30.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EEQ37207.1 - 1.8e-06 27.7 8.6 1.8e-06 27.7 8.6 3.0 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Pyridoxal_deC PF00282.19 EEQ37208.1 - 3.9e-70 236.4 0.0 5.1e-70 236.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EEQ37208.1 - 0.00077 18.8 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EEQ37208.1 - 0.034 13.1 0.0 0.066 12.2 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V OKR_DC_1 PF01276.20 EEQ37208.1 - 0.049 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain NdhS PF11623.8 EEQ37208.1 - 0.19 11.4 0.4 10 5.9 0.2 2.5 2 0 0 2 2 2 0 NAD(P)H dehydrogenase subunit S MMS1_N PF10433.9 EEQ37209.1 - 3.6e-99 332.6 2.3 3.6e-99 332.6 2.3 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EEQ37209.1 - 1.4e-75 254.6 2.5 2.2e-75 254.0 0.6 2.3 3 0 0 3 3 3 1 CPSF A subunit region DUF2012 PF09430.10 EEQ37209.1 - 0.13 12.4 0.0 0.57 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) ANAPC4_WD40 PF12894.7 EEQ37209.1 - 0.13 12.6 0.0 9.6 6.6 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Forkhead PF00250.18 EEQ37210.1 - 4.1e-35 119.9 0.8 4.1e-35 119.9 0.8 2.0 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 EEQ37210.1 - 1e-08 35.4 0.0 2.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain FHA_2 PF17913.1 EEQ37210.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 FHA domain WD40 PF00400.32 EEQ37211.1 - 1.8e-13 50.7 11.0 0.00013 22.7 0.6 6.4 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37211.1 - 9.6e-10 38.6 1.7 0.11 12.8 0.3 4.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ37211.1 - 0.00015 21.7 0.9 0.18 11.7 1.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EEQ37212.1 - 6.4e-06 26.8 2.6 3.6e-05 24.4 0.8 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37212.1 - 0.028 14.7 0.0 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Vps8 PF12816.7 EEQ37213.1 - 8.6e-46 155.9 4.8 8.6e-46 155.9 4.8 2.6 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_11 PF17123.5 EEQ37213.1 - 0.018 14.8 0.1 0.063 13.0 0.1 2.0 1 0 0 1 1 1 0 RING-like zinc finger MMS19_N PF14500.6 EEQ37213.1 - 0.033 13.8 2.3 0.076 12.6 1.0 2.3 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II zf-RING_5 PF14634.6 EEQ37213.1 - 0.034 14.1 1.5 0.12 12.4 0.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Vps39_1 PF10366.9 EEQ37213.1 - 0.05 13.9 2.1 0.7 10.2 0.0 3.8 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 1 zf-rbx1 PF12678.7 EEQ37213.1 - 0.052 13.9 0.1 0.16 12.3 0.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ37213.1 - 0.066 13.6 0.3 0.066 13.6 0.3 2.2 2 0 0 2 2 2 0 Ring finger domain TPR_12 PF13424.6 EEQ37213.1 - 0.14 12.5 0.0 5.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Chitin_synth_1 PF01644.17 EEQ37214.1 - 9.4e-64 214.3 0.5 1.4e-63 213.7 0.5 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EEQ37214.1 - 8.3e-25 86.5 0.0 2.2e-24 85.2 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EEQ37214.1 - 1.2e-20 73.7 0.0 1.2e-16 60.4 0.0 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EEQ37214.1 - 2.4e-13 50.5 4.3 1.7e-12 47.7 4.3 2.4 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 EEQ37214.1 - 0.057 12.9 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 E1-E2_ATPase PF00122.20 EEQ37215.1 - 5.8e-38 130.2 5.7 1.5e-37 128.8 4.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ37215.1 - 8.2e-19 68.7 0.1 1.8e-18 67.6 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EEQ37215.1 - 4.5e-11 42.3 0.0 1.2e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EEQ37215.1 - 0.0019 18.0 1.4 0.0033 17.2 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ37215.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Cation transport ATPase (P-type) SIS_2 PF13580.6 EEQ37215.1 - 0.1 12.6 0.2 2.6 8.1 0.0 2.6 2 0 0 2 2 2 0 SIS domain PUF PF00806.19 EEQ37216.1 - 1.4e-61 200.8 5.8 9.4e-09 34.5 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Fungal_trans_2 PF11951.8 EEQ37217.1 - 1e-12 47.6 1.6 6e-12 45.1 1.6 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ37217.1 - 2.8e-09 36.9 12.8 5.4e-09 36.0 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.17 EEQ37218.1 - 9.1e-161 535.4 25.7 1e-160 535.2 25.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Proteasome PF00227.26 EEQ37219.1 - 3.4e-33 114.7 0.1 3.9e-33 114.5 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Hist_deacetyl PF00850.19 EEQ37220.1 - 1.1e-83 281.3 0.0 1.5e-83 280.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 EEQ37221.1 - 4.5e-55 186.8 0.7 8.1e-55 186.0 0.7 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37221.1 - 3.1e-36 125.0 0.0 5.2e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ37221.1 - 7.1e-05 21.8 1.1 0.00012 21.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEQ37221.1 - 0.00088 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Rhodanese PF00581.20 EEQ37222.1 - 1.2e-08 35.5 0.0 2.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain DUF1676 PF07898.13 EEQ37224.1 - 0.1 12.6 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) adh_short PF00106.25 EEQ37225.1 - 5.1e-87 290.4 10.5 1.1e-46 158.8 0.8 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ37225.1 - 1.1e-71 241.1 7.4 2e-38 132.3 0.8 3.1 2 2 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ37225.1 - 7.1e-34 117.3 4.9 1.5e-16 60.8 0.5 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.19 EEQ37225.1 - 6.3e-33 113.0 0.0 1.3e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DNA_pol_phi PF04931.13 EEQ37225.1 - 0.037 12.1 1.0 0.052 11.7 1.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EEQ37225.1 - 0.088 13.2 12.6 0.21 12.0 12.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EEQ37225.1 - 0.9 8.8 7.1 1.5 8.1 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein PglL_A PF15864.5 EEQ37225.1 - 1.7 8.4 7.6 8.1 6.3 0.8 2.4 2 0 0 2 2 2 0 Protein glycosylation ligase PBP1_TM PF14812.6 EEQ37225.1 - 5.6 7.4 8.4 11 6.5 8.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dicty_REP PF05086.12 EEQ37225.1 - 7.5 4.4 6.4 10 3.9 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Acyltransferase PF01553.21 EEQ37226.1 - 4.9e-11 42.4 0.0 1.5e-10 40.8 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase SRI PF08236.11 EEQ37226.1 - 4.6 7.5 9.0 13 6.0 0.1 3.5 4 0 0 4 4 4 0 SRI (Set2 Rpb1 interacting) domain DNA_ligase_A_M PF01068.21 EEQ37227.1 - 5.9e-63 212.2 0.5 1e-62 211.4 0.5 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EEQ37227.1 - 2e-46 158.4 0.1 4.9e-46 157.2 0.0 1.7 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EEQ37227.1 - 6.2e-25 87.7 0.0 1.6e-24 86.4 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EEQ37227.1 - 0.00013 22.3 0.1 0.00027 21.3 0.1 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_OB_2 PF14743.6 EEQ37227.1 - 0.0044 17.0 0.4 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 DNA ligase OB-like domain Actin PF00022.19 EEQ37228.1 - 3.3e-23 82.0 0.1 4.8e-22 78.1 0.1 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EEQ37228.1 - 3.9e-06 25.9 0.0 2.9e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Eisosome1 PF12757.7 EEQ37230.1 - 2.6e-20 72.9 8.1 2.6e-20 72.9 8.1 6.7 3 2 4 7 7 7 1 Eisosome protein 1 DUF1358 PF07096.11 EEQ37231.1 - 0.12 12.3 0.7 0.21 11.6 0.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1358) Histone PF00125.24 EEQ37232.1 - 1.3e-43 148.4 0.0 1.5e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEQ37232.1 - 0.00017 21.9 0.0 0.00022 21.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEQ37232.1 - 0.00058 19.9 0.0 0.00087 19.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 EEQ37232.1 - 0.0014 18.8 0.6 0.0023 18.2 0.6 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EEQ37232.1 - 0.06 13.4 0.0 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L41 PF05162.13 EEQ37233.1 - 0.24 11.5 2.0 0.41 10.8 2.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L41 zf-C2H2 PF00096.26 EEQ37234.1 - 3.2e-12 46.2 14.3 5.7e-07 29.7 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ37234.1 - 1.8e-08 34.5 13.7 0.00014 22.4 2.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ37234.1 - 8.9e-08 32.2 8.1 3.7e-05 23.9 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EEQ37234.1 - 1.2e-07 31.9 20.0 9.9e-06 25.8 5.3 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 EEQ37234.1 - 0.00035 20.9 8.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.15 EEQ37234.1 - 0.0021 18.0 4.9 0.7 10.0 0.5 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.6 EEQ37234.1 - 0.013 15.4 15.9 0.038 14.0 4.3 3.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EEQ37234.1 - 0.038 13.8 13.6 0.098 12.4 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 EEQ37234.1 - 0.043 14.2 6.1 0.7 10.3 1.3 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-AN1 PF01428.16 EEQ37234.1 - 0.082 13.1 2.9 2.2 8.5 0.3 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zinc-ribbons_6 PF07191.12 EEQ37234.1 - 0.14 12.2 1.1 0.29 11.2 1.0 1.6 2 0 0 2 2 1 0 zinc-ribbons zf-Di19 PF05605.12 EEQ37234.1 - 0.23 11.8 7.3 1 9.7 7.5 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.15 EEQ37234.1 - 0.28 11.1 3.0 0.28 11.1 0.9 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf_UBZ PF18439.1 EEQ37234.1 - 0.28 10.8 4.1 1.5 8.5 0.4 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 EEQ37234.1 - 0.41 10.3 5.2 3.7 7.3 0.2 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 EEQ37234.1 - 0.8 10.2 9.7 3.4 8.2 0.8 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger SBF_like PF13593.6 EEQ37235.1 - 6.3e-122 406.8 20.4 7.5e-122 406.5 20.4 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EEQ37235.1 - 1.7e-10 40.9 6.5 1.7e-10 40.9 6.5 1.7 1 1 0 1 1 1 1 Sodium Bile acid symporter family Colicin_im PF03857.13 EEQ37235.1 - 0.015 15.3 4.5 0.038 13.9 4.5 1.6 1 0 0 1 1 1 0 Colicin immunity protein KdgT PF03812.13 EEQ37235.1 - 5.3 6.3 14.9 0.12 11.6 4.6 2.6 2 1 0 2 2 2 0 2-keto-3-deoxygluconate permease SH3_1 PF00018.28 EEQ37236.1 - 2.1e-10 40.1 0.0 3.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain FCH PF00611.23 EEQ37236.1 - 4.7e-10 39.6 0.6 4.7e-10 39.6 0.6 2.8 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EEQ37236.1 - 1e-07 31.7 0.1 1.9e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ37236.1 - 0.0021 17.7 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4298 PF14131.6 EEQ37236.1 - 0.39 10.7 3.7 8.7 6.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) Exonuc_VII_L PF02601.15 EEQ37236.1 - 1.9 8.0 6.9 3.5 7.1 6.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EEQ37236.1 - 4.5 6.5 6.4 7.6 5.8 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Jnk-SapK_ap_N PF09744.9 EEQ37236.1 - 4.6 7.4 9.4 2 8.6 5.3 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Aldo_ket_red PF00248.21 EEQ37237.1 - 4.7e-43 147.5 0.0 5.9e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IF4E PF01652.18 EEQ37237.1 - 0.055 13.3 0.2 0.096 12.5 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic initiation factor 4E PRKG1_interact PF15898.5 EEQ37237.1 - 0.17 12.8 0.9 0.37 11.7 0.9 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain PC4 PF02229.16 EEQ37238.1 - 1.1e-21 76.2 1.3 1.1e-21 76.1 0.1 1.7 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) TssC PF17541.2 EEQ37238.1 - 0.035 12.9 3.2 0.043 12.6 3.2 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssC, VipB LANC_like PF05147.13 EEQ37238.1 - 0.061 11.9 0.1 0.059 11.9 0.1 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein CorA PF01544.18 EEQ37239.1 - 8e-36 123.8 7.2 1.5e-17 63.8 0.4 3.9 4 1 0 4 4 4 3 CorA-like Mg2+ transporter protein Ribosomal_L32p PF01783.23 EEQ37239.1 - 0.3 11.4 3.0 0.84 9.9 3.0 1.8 1 0 0 1 1 1 0 Ribosomal L32p protein family Bap31 PF05529.12 EEQ37240.1 - 1.8e-34 118.5 6.0 1.8e-34 118.5 6.0 1.4 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EEQ37240.1 - 1.6e-07 31.2 4.6 1.6e-07 31.2 4.6 2.8 3 0 0 3 3 3 1 Bap31/Bap29 cytoplasmic coiled-coil domain DUF722 PF05263.11 EEQ37240.1 - 0.00053 20.2 1.3 0.00083 19.6 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF722) ADIP PF11559.8 EEQ37240.1 - 0.011 15.8 1.6 0.016 15.3 1.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4446 PF14584.6 EEQ37240.1 - 0.027 14.5 0.5 0.06 13.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) OmpH PF03938.14 EEQ37240.1 - 0.59 10.5 7.2 0.5 10.7 3.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mannosyl_trans3 PF11051.8 EEQ37241.1 - 9.1e-80 267.9 0.0 1.3e-79 267.5 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative CN_hydrolase PF00795.22 EEQ37242.1 - 1.5e-56 191.6 0.0 1.8e-56 191.4 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_1 PF00561.20 EEQ37243.1 - 3.9e-24 85.7 0.0 4.4e-23 82.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ37243.1 - 8.3e-16 59.2 0.0 1.3e-15 58.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ37243.1 - 2e-11 43.6 0.0 2.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EEQ37243.1 - 2.1e-05 24.8 0.0 2.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EEQ37243.1 - 2.7e-05 24.0 0.0 0.089 12.5 0.0 2.2 1 1 1 2 2 2 2 PGAP1-like protein DUF676 PF05057.14 EEQ37243.1 - 0.00073 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EEQ37243.1 - 0.0042 17.0 0.0 0.0051 16.7 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Esterase PF00756.20 EEQ37243.1 - 0.017 14.7 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF1057 PF06342.12 EEQ37243.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) LIDHydrolase PF10230.9 EEQ37243.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase PF07224.11 EEQ37243.1 - 0.098 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DUF915 PF06028.11 EEQ37243.1 - 0.12 11.6 0.0 6.8 5.9 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0227 PF05728.12 EEQ37243.1 - 0.15 12.0 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) AAA PF00004.29 EEQ37244.1 - 1.4e-95 316.8 0.0 1.2e-47 161.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ37244.1 - 1.9e-22 78.8 0.1 5e-10 39.0 0.0 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EEQ37244.1 - 4.4e-15 55.8 0.0 6.1e-08 32.6 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EEQ37244.1 - 5.6e-13 49.4 0.0 5.5e-05 23.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEQ37244.1 - 8.6e-12 45.8 4.0 0.00047 20.6 0.1 5.2 4 2 1 5 5 4 2 AAA ATPase domain AAA_5 PF07728.14 EEQ37244.1 - 6.9e-11 42.3 0.3 9.1e-05 22.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EEQ37244.1 - 3.2e-10 40.3 0.0 0.00065 19.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEQ37244.1 - 2.3e-09 37.6 4.2 0.0065 16.7 0.0 5.7 5 2 1 6 6 3 2 AAA domain AAA_14 PF13173.6 EEQ37244.1 - 1.1e-08 35.2 0.0 0.0023 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EEQ37244.1 - 1.2e-08 35.6 0.0 0.00022 21.8 0.0 3.6 3 1 0 3 3 2 2 AAA domain TIP49 PF06068.13 EEQ37244.1 - 2.1e-08 33.8 0.0 0.00056 19.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain ABC_tran PF00005.27 EEQ37244.1 - 4.8e-08 33.6 0.0 0.0062 17.1 0.0 3.1 2 0 0 2 2 2 2 ABC transporter RNA_helicase PF00910.22 EEQ37244.1 - 6.1e-08 33.0 0.0 0.0032 17.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EEQ37244.1 - 1.1e-07 32.2 0.1 0.0046 17.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain Cytidylate_kin2 PF13189.6 EEQ37244.1 - 2.1e-07 31.3 0.2 0.00018 21.7 0.0 3.0 3 0 0 3 3 2 1 Cytidylate kinase-like family Mg_chelatase PF01078.21 EEQ37244.1 - 3.2e-07 29.9 0.1 0.02 14.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EEQ37244.1 - 4.3e-07 29.4 0.1 0.034 13.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.17 EEQ37244.1 - 1.1e-06 28.5 0.1 0.051 13.3 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein Rad17 PF03215.15 EEQ37244.1 - 1.3e-06 28.5 0.0 0.0051 16.8 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_17 PF13207.6 EEQ37244.1 - 1.8e-06 28.4 0.0 0.0062 17.0 0.0 3.5 2 1 0 2 2 2 1 AAA domain Vps4_C PF09336.10 EEQ37244.1 - 5e-06 26.4 0.0 0.042 13.8 0.0 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain AAA_3 PF07726.11 EEQ37244.1 - 6.4e-06 26.1 0.0 0.041 13.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EEQ37244.1 - 2.1e-05 24.5 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EEQ37244.1 - 2.2e-05 23.8 0.1 1.2 8.3 0.0 3.7 4 0 0 4 4 3 2 NB-ARC domain SKI PF01202.22 EEQ37244.1 - 2.2e-05 24.6 0.0 0.033 14.3 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase ATPase_2 PF01637.18 EEQ37244.1 - 2.9e-05 24.1 0.0 0.32 10.9 0.0 3.8 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EEQ37244.1 - 3e-05 23.6 0.0 0.057 12.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EEQ37244.1 - 3.4e-05 23.7 0.0 0.087 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 EEQ37244.1 - 5.5e-05 22.4 0.0 0.089 11.9 0.0 2.9 3 0 0 3 3 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 EEQ37244.1 - 6e-05 23.0 0.0 0.3 11.0 0.0 3.1 3 0 0 3 3 3 2 NACHT domain AAA_25 PF13481.6 EEQ37244.1 - 7.9e-05 22.3 0.5 0.25 10.9 0.0 3.6 3 1 1 4 4 3 1 AAA domain Sigma54_activat PF00158.26 EEQ37244.1 - 0.00022 21.0 0.0 0.22 11.2 0.0 3.0 2 1 1 3 3 3 1 Sigma-54 interaction domain ATPase PF06745.13 EEQ37244.1 - 0.00059 19.3 0.2 2.8 7.2 0.0 3.4 3 0 0 3 3 3 1 KaiC Viral_helicase1 PF01443.18 EEQ37244.1 - 0.00061 19.6 0.0 0.53 10.0 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EEQ37244.1 - 0.00089 19.1 8.9 0.73 9.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain Parvo_NS1 PF01057.17 EEQ37244.1 - 0.00091 18.4 0.1 0.65 9.0 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 EEQ37244.1 - 0.0023 18.1 0.0 2.9 8.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 EEQ37244.1 - 0.0028 17.6 0.0 0.24 11.2 0.0 3.2 3 1 0 3 3 2 1 Bacterial dnaA protein NTPase_1 PF03266.15 EEQ37244.1 - 0.0039 17.1 0.0 1.6 8.6 0.0 2.8 2 0 0 2 2 2 1 NTPase PduV-EutP PF10662.9 EEQ37244.1 - 0.005 16.6 0.0 2.1 8.1 0.0 2.9 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin PF02224.18 EEQ37244.1 - 0.0055 16.5 0.0 0.45 10.2 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase PhoH PF02562.16 EEQ37244.1 - 0.0057 16.1 0.1 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein TniB PF05621.11 EEQ37244.1 - 0.009 15.4 0.1 7.5 5.9 0.0 3.6 3 1 0 4 4 3 0 Bacterial TniB protein AAA_19 PF13245.6 EEQ37244.1 - 0.011 16.1 0.0 1.9 8.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EEQ37244.1 - 0.017 15.2 0.6 0.74 9.9 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ37244.1 - 0.021 14.7 0.7 0.38 10.6 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase SRPRB PF09439.10 EEQ37244.1 - 0.024 14.1 0.0 5.5 6.4 0.0 3.0 3 0 0 3 3 2 0 Signal recognition particle receptor beta subunit CPT PF07931.12 EEQ37244.1 - 0.024 14.5 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein FeoB_N PF02421.18 EEQ37244.1 - 0.032 13.8 0.1 0.84 9.2 0.0 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AFG1_ATPase PF03969.16 EEQ37244.1 - 0.035 13.0 0.1 6.2 5.6 0.0 2.5 2 0 0 2 2 2 0 AFG1-like ATPase ADK PF00406.22 EEQ37244.1 - 0.044 13.9 0.0 3.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Adenylate kinase KTI12 PF08433.10 EEQ37244.1 - 0.045 13.2 1.9 3.4 7.0 0.0 3.7 3 1 1 4 4 4 0 Chromatin associated protein KTI12 AAA_29 PF13555.6 EEQ37244.1 - 0.05 13.4 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain KAP_NTPase PF07693.14 EEQ37244.1 - 0.055 12.7 0.0 2 7.6 0.0 2.7 2 1 0 2 2 2 0 KAP family P-loop domain TERF2_RBM PF16772.5 EEQ37244.1 - 0.065 12.7 0.0 0.24 10.8 0.0 2.0 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif AAA_30 PF13604.6 EEQ37244.1 - 0.066 12.9 1.7 8.4 6.1 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.6 EEQ37244.1 - 0.21 12.1 0.0 0.21 12.1 0.0 3.8 4 0 0 4 4 2 0 AAA domain DUF2075 PF09848.9 EEQ37244.1 - 0.26 10.5 3.8 8.9 5.4 0.0 3.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2075) Hydin_ADK PF17213.3 EEQ37244.1 - 0.47 10.7 5.7 21 5.3 0.0 3.5 4 0 0 4 4 3 0 Hydin Adenylate kinase-like domain HSP9_HSP12 PF04119.12 EEQ37245.1 - 1.2e-25 89.7 4.3 1.2e-25 89.7 4.3 2.4 2 1 0 2 2 2 1 Heat shock protein 9/12 EspB PF05802.11 EEQ37245.1 - 0.0099 15.9 8.5 0.013 15.5 8.5 1.2 1 0 0 1 1 1 1 Enterobacterial EspB protein Mobilization_B PF17511.2 EEQ37245.1 - 0.38 11.1 5.8 0.49 10.8 5.6 1.3 1 1 0 1 1 1 0 Mobilization protein B YtxH PF12732.7 EEQ37245.1 - 0.53 10.9 12.9 2 9.0 5.0 2.4 1 1 1 2 2 2 0 YtxH-like protein RRM_1 PF00076.22 EEQ37246.1 - 3.9e-05 23.4 0.1 0.002 17.9 0.1 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dopey_N PF04118.14 EEQ37248.1 - 1.9e-108 362.2 2.9 9.1e-108 360.0 0.4 2.8 2 0 0 2 2 2 1 Dopey, N-terminal Abhydrolase_2 PF02230.16 EEQ37249.1 - 2.8e-53 181.0 0.0 3.3e-53 180.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EEQ37249.1 - 1.6e-09 37.8 0.0 9e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EEQ37249.1 - 4.1e-07 30.8 0.0 7.9e-07 29.9 0.0 1.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ37249.1 - 8.8e-07 28.4 0.0 0.0022 17.3 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DLH PF01738.18 EEQ37249.1 - 2.9e-05 23.7 0.0 3.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EEQ37249.1 - 0.00014 21.6 0.1 0.061 13.0 0.0 2.7 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EEQ37249.1 - 0.0028 17.2 0.0 0.063 12.8 0.0 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family Cutinase PF01083.22 EEQ37249.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Cutinase PGAP1 PF07819.13 EEQ37249.1 - 0.033 13.9 0.0 0.08 12.6 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.25 EEQ37249.1 - 0.034 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Dus PF01207.17 EEQ37250.1 - 1.3e-74 251.1 0.0 1.7e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-H2C2_2 PF13465.6 EEQ37251.1 - 1.3e-07 31.7 6.9 2.6e-06 27.6 3.9 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 EEQ37251.1 - 1.7e-07 31.3 11.3 0.0014 18.9 3.2 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ37251.1 - 0.00015 22.3 10.8 0.017 15.9 2.5 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EEQ37251.1 - 0.52 10.1 6.7 0.1 12.4 0.6 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EEQ37251.1 - 2.4 8.6 4.3 6.8 7.2 0.7 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glyco_tran_28_C PF04101.16 EEQ37252.1 - 2.1e-20 73.4 0.1 3.6e-20 72.6 0.1 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 EEQ37252.1 - 0.096 11.9 0.1 0.16 11.2 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 1 TFIID-18kDa PF02269.16 EEQ37253.1 - 1.2e-17 63.7 0.0 1.2e-17 63.7 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 EEQ37253.1 - 0.0016 18.7 0.2 0.0033 17.7 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EEQ37253.1 - 0.044 14.2 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 CENP-S protein Med19 PF10278.9 EEQ37253.1 - 0.79 9.6 11.8 1 9.3 11.8 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF1700 PF08006.11 EEQ37254.1 - 0.13 11.8 5.8 0.26 10.8 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) LapA_dom PF06305.11 EEQ37254.1 - 4.1 7.3 5.5 4.4 7.2 1.9 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain RINGv PF12906.7 EEQ37256.1 - 1.6e-18 66.5 10.9 3.3e-18 65.5 10.9 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EEQ37256.1 - 0.00077 19.7 9.3 0.0015 18.8 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EEQ37256.1 - 0.018 15.2 5.2 0.037 14.2 5.2 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain YyzF PF14116.6 EEQ37256.1 - 0.045 13.8 1.9 3.9 7.6 0.3 2.3 2 0 0 2 2 2 0 YyzF-like protein Zf_RING PF16744.5 EEQ37256.1 - 0.17 12.0 4.5 1.3 9.1 4.2 2.2 1 1 1 2 2 2 0 KIAA1045 RING finger zf-ANAPC11 PF12861.7 EEQ37256.1 - 0.27 11.3 5.8 0.65 10.1 5.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_2 PF03107.16 EEQ37256.1 - 1 9.8 8.8 4.5 7.7 2.4 2.4 1 1 1 2 2 2 0 C1 domain zf-RING_4 PF14570.6 EEQ37256.1 - 1.3 8.9 9.7 1.5 8.7 7.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Cys_Knot_tox PF17486.2 EEQ37256.1 - 3.5 7.9 8.8 28 5.0 8.4 2.1 1 1 1 2 2 2 0 Cystine knot toxins Zn_ribbon_17 PF17120.5 EEQ37256.1 - 4.5 7.0 7.6 34 4.2 8.1 2.1 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 EEQ37256.1 - 4.9 7.1 8.9 16 5.5 8.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PMT PF02366.18 EEQ37258.1 - 4.4e-81 272.1 11.7 6.9e-81 271.4 11.7 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 EEQ37258.1 - 1.3e-47 162.1 0.1 4.8e-47 160.2 0.1 1.8 1 1 1 2 2 2 1 MIR domain PMT_4TMC PF16192.5 EEQ37258.1 - 4.4e-31 108.0 9.4 1.1e-30 106.8 9.4 1.7 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT_2 PF13231.6 EEQ37258.1 - 9.8e-05 22.6 8.6 9.8e-05 22.6 8.6 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ins145_P3_rec PF08709.11 EEQ37258.1 - 0.11 11.7 0.0 8.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor Rrn6 PF10214.9 EEQ37259.1 - 2.2e-29 102.6 43.1 5.4e-26 91.4 2.8 4.1 2 1 1 3 3 3 2 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 EEQ37259.1 - 0.35 9.1 8.1 0.55 8.5 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Menin PF05053.13 EEQ37259.1 - 2 6.7 6.5 3.9 5.7 6.5 1.4 1 0 0 1 1 1 0 Menin Trp_syntA PF00290.20 EEQ37260.1 - 1.2e-91 306.1 0.4 1.8e-91 305.6 0.4 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EEQ37260.1 - 3.6e-47 161.2 1.5 6.8e-47 160.3 1.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Nodulin-like PF06813.13 EEQ37262.1 - 4.6e-13 49.2 10.8 4.6e-13 49.2 10.8 2.6 2 1 0 2 2 2 2 Nodulin-like Formyl_trans_N PF00551.19 EEQ37263.1 - 6.8e-28 97.6 0.0 9.1e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EEQ37263.1 - 2.8e-06 27.5 0.0 4.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain VPS13_C PF16909.5 EEQ37264.1 - 3.1e-76 255.1 6.7 3.7e-70 235.3 0.7 2.5 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EEQ37264.1 - 2.9e-60 204.0 0.3 2.9e-60 204.0 0.3 1.6 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 ATG_C PF09333.11 EEQ37264.1 - 7.3e-06 26.2 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 EEQ37264.1 - 0.011 14.6 0.2 0.016 14.1 0.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SHR-BD PF06650.12 EEQ37265.1 - 3.3e-08 33.2 1.7 0.0025 17.3 0.0 4.0 3 2 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EEQ37267.1 - 9.3e-49 166.0 7.8 2.2e-48 164.7 0.6 3.4 4 0 0 4 4 4 2 Repeating coiled region of VPS13 VPS13 PF16908.5 EEQ37268.1 - 4.3e-77 259.1 1.4 8.5e-77 258.1 1.4 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EEQ37268.1 - 6.8e-41 139.0 0.4 1.8e-40 137.7 0.4 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 EEQ37268.1 - 5.3e-28 98.0 0.0 3.1e-27 95.5 0.0 2.3 3 0 0 3 3 3 1 Repeating coiled region of VPS13 PNPase PF03726.14 EEQ37268.1 - 0.17 12.4 2.3 1.1 9.8 0.1 3.0 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Epimerase PF01370.21 EEQ37269.1 - 8.9e-19 67.9 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ37269.1 - 4e-11 42.4 0.0 5.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EEQ37269.1 - 4.8e-10 39.6 0.0 2.3e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EEQ37269.1 - 9.8e-10 38.3 0.0 1.3e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEQ37269.1 - 1.2e-07 31.1 0.0 0.00066 18.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 EEQ37269.1 - 8.2e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ37269.1 - 0.00013 21.9 0.3 0.0012 18.7 0.3 2.1 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EEQ37269.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.17 EEQ37269.1 - 0.016 15.8 0.0 0.037 14.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 EEQ37269.1 - 0.043 13.4 0.0 0.078 12.5 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 EEQ37269.1 - 0.11 11.6 0.1 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EEQ37269.1 - 0.17 11.0 0.0 0.49 9.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EEQ37270.1 - 3.8e-19 69.1 0.0 6.1e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ37270.1 - 1.9e-11 43.5 0.0 3e-11 42.9 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEQ37270.1 - 2e-09 37.3 0.0 2.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EEQ37270.1 - 3.2e-09 36.9 0.0 4.1e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EEQ37270.1 - 4.4e-08 32.6 0.2 0.0068 15.6 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein adh_short PF00106.25 EEQ37270.1 - 4.6e-06 26.2 1.0 3.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.17 EEQ37270.1 - 0.00091 19.8 0.1 0.0049 17.4 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 EEQ37270.1 - 0.0051 16.8 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 2 KR domain NAD_binding_2 PF03446.15 EEQ37270.1 - 0.016 15.4 0.0 0.03 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.17 EEQ37270.1 - 0.019 14.1 0.1 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Shikimate_DH PF01488.20 EEQ37270.1 - 0.04 14.0 0.0 0.072 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.15 EEQ37270.1 - 0.083 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3543 PF12063.8 EEQ37271.1 - 1.3e-85 286.8 0.5 2.5e-85 285.9 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EEQ37271.1 - 1.7e-62 211.2 0.0 3.2e-62 210.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37271.1 - 2.6e-43 148.2 0.0 4.3e-43 147.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ37271.1 - 0.00023 20.6 0.0 0.0085 15.4 0.0 2.6 3 0 0 3 3 3 1 Kinase-like MIT PF04212.18 EEQ37271.1 - 0.035 14.2 0.3 7.2 6.8 0.1 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 EEQ37272.1 - 9.9e-53 179.2 0.0 1.7e-51 175.1 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37272.1 - 1e-26 93.8 0.0 3.4e-26 92.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ37272.1 - 2.4e-08 33.7 0.0 4.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ37272.1 - 0.43 10.4 1.9 1.2 9.0 0.0 2.5 3 1 1 4 4 4 0 Phosphotransferase enzyme family CinA PF02464.17 EEQ37274.1 - 1.1e-31 109.4 0.1 1.6e-31 109.0 0.1 1.2 1 0 0 1 1 1 1 Competence-damaged protein HlyD_D4 PF16572.5 EEQ37274.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Septin PF00735.18 EEQ37275.1 - 4.1e-110 367.5 2.0 4.1e-110 367.5 2.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EEQ37275.1 - 4.9e-05 23.4 0.3 4.9e-05 23.4 0.3 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EEQ37275.1 - 0.00043 20.8 6.6 0.014 15.9 6.6 2.5 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EEQ37275.1 - 0.00091 19.2 0.4 0.00091 19.2 0.4 2.9 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EEQ37275.1 - 0.0023 18.2 1.0 0.0077 16.5 0.3 2.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ37275.1 - 0.0023 18.3 0.5 0.019 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Strep_SA_rep PF06696.11 EEQ37275.1 - 0.0032 17.4 2.1 0.0032 17.4 2.1 2.4 2 0 0 2 2 2 1 Streptococcal surface antigen repeat RNA_helicase PF00910.22 EEQ37275.1 - 0.0099 16.3 0.3 1.1 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 EEQ37275.1 - 0.013 15.2 0.6 0.043 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EEQ37275.1 - 0.015 15.5 0.1 0.052 13.8 0.1 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EEQ37275.1 - 0.018 14.8 0.3 0.081 12.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Exonuc_VII_L PF02601.15 EEQ37275.1 - 0.043 13.4 4.1 0.07 12.7 4.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit GTP_EFTU PF00009.27 EEQ37275.1 - 0.51 9.9 9.4 0.12 11.9 0.4 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FAM76 PF16046.5 EEQ37275.1 - 0.85 8.9 7.9 1.4 8.2 7.9 1.3 1 0 0 1 1 1 0 FAM76 protein AIG1 PF04548.16 EEQ37275.1 - 0.97 8.7 7.5 0.048 13.0 1.1 2.2 2 1 0 2 2 2 0 AIG1 family DUF1090 PF06476.12 EEQ37275.1 - 6.9 6.8 16.6 13 6.0 16.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) UPF0121 PF03661.13 EEQ37276.1 - 7.5e-28 97.5 9.7 9.5e-28 97.2 9.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) HSP70 PF00012.20 EEQ37277.1 - 7.9e-261 866.5 10.0 9e-261 866.3 10.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ37277.1 - 5.7e-18 64.8 0.0 8.5e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EEQ37277.1 - 0.0003 20.6 0.0 0.0019 17.9 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EEQ37277.1 - 0.016 14.5 0.3 0.066 12.5 0.0 2.2 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 EEQ37277.1 - 0.046 13.2 0.0 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Ppx-GppA PF02541.16 EEQ37277.1 - 0.057 12.8 0.4 0.39 10.1 0.0 2.2 2 0 0 2 2 2 0 Ppx/GppA phosphatase family StbA PF06406.11 EEQ37277.1 - 0.09 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 StbA protein PMBR PF09373.10 EEQ37277.1 - 1.5 9.1 0.0 1.5 9.1 0.0 2.6 3 0 0 3 3 3 0 Pseudomurein-binding repeat AMP-binding PF00501.28 EEQ37279.1 - 4e-89 299.1 0.2 5.6e-89 298.6 0.0 1.3 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ37279.1 - 1.5e-24 86.7 2.3 3.9e-24 85.4 0.7 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EEQ37279.1 - 1.4e-21 76.1 0.0 3.2e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Mannosyl_trans2 PF04188.13 EEQ37280.1 - 3.2e-45 155.3 30.2 1.3e-41 143.3 30.2 2.3 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) DUF3007 PF11460.8 EEQ37280.1 - 1.5 9.1 6.7 8.2 6.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) DUF3445 PF11927.8 EEQ37281.1 - 7.8e-78 261.2 0.0 9.8e-78 260.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Histone PF00125.24 EEQ37282.1 - 5.3e-51 172.4 2.8 5.9e-51 172.2 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEQ37282.1 - 3.8e-06 27.2 0.0 5.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEQ37282.1 - 5e-05 23.4 0.5 8e-05 22.7 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EEQ37282.1 - 5.6e-05 23.7 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EEQ37282.1 - 0.0052 17.0 0.6 0.0079 16.5 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EEQ37282.1 - 0.023 14.8 0.1 0.039 14.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 EEQ37283.1 - 9.1e-10 38.6 0.1 1.1e-09 38.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EEQ37283.1 - 1.7e-05 24.9 0.1 2.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EEQ37283.1 - 3.8e-05 23.9 0.1 6.5e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ37283.1 - 8.4e-05 22.9 0.1 9.8e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEQ37283.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EEQ37283.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EEQ37283.1 - 0.0047 16.9 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 EEQ37283.1 - 0.019 14.8 0.2 0.023 14.5 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TAFII28 PF04719.14 EEQ37283.1 - 0.051 13.7 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TFIID_20kDa PF03847.13 EEQ37283.1 - 0.069 13.7 0.1 0.13 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF3605 PF12239.8 EEQ37284.1 - 5.2e-50 169.7 2.4 6.3e-50 169.5 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) TEX12 PF15219.6 EEQ37284.1 - 0.084 13.2 0.0 2.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Testis-expressed 12 His_Phos_1 PF00300.22 EEQ37285.1 - 1.5e-35 122.6 0.0 8.6e-27 94.1 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DMRL_synthase PF00885.19 EEQ37285.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase zf-C2H2 PF00096.26 EEQ37286.1 - 9.9e-07 28.9 1.2 0.0074 16.7 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ37286.1 - 0.00044 20.9 3.4 0.54 11.3 0.0 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 EEQ37286.1 - 0.027 14.8 0.0 0.096 13.0 0.0 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_ZIC PF18366.1 EEQ37286.1 - 0.033 14.3 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_jaz PF12171.8 EEQ37286.1 - 0.23 11.8 2.2 3.6 8.0 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EEQ37286.1 - 7.5 7.2 6.0 30 5.3 0.1 3.0 3 1 0 3 3 3 0 Zinc-finger double domain PQ-loop PF04193.14 EEQ37287.1 - 3.4e-15 55.6 5.4 2.4e-08 33.6 0.5 2.9 2 1 1 3 3 3 2 PQ loop repeat ER_lumen_recept PF00810.18 EEQ37287.1 - 8.4e-05 23.4 2.5 0.00054 20.8 2.5 2.1 1 1 0 1 1 1 1 ER lumen protein retaining receptor Peptidase_U4 PF03419.13 EEQ37287.1 - 4.4 6.5 6.6 14 4.8 0.1 2.1 2 0 0 2 2 2 0 Sporulation factor SpoIIGA ICL PF00463.21 EEQ37288.1 - 5.6e-299 992.0 3.1 6.4e-299 991.8 3.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EEQ37288.1 - 1.4e-11 44.3 0.1 4e-11 42.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase F-box PF00646.33 EEQ37289.1 - 0.013 15.4 0.1 0.026 14.4 0.1 1.5 1 0 0 1 1 1 0 F-box domain Osteoregulin PF07175.11 EEQ37289.1 - 0.082 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Osteoregulin F-box-like PF12937.7 EEQ37289.1 - 0.16 11.9 0.1 0.44 10.5 0.1 1.8 1 0 0 1 1 1 0 F-box-like DUF3915 PF13054.6 EEQ37289.1 - 0.24 11.4 3.3 0.55 10.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Atrophin-1 PF03154.15 EEQ37289.1 - 1.5 7.0 7.8 3 6.0 7.8 1.4 1 0 0 1 1 1 0 Atrophin-1 family Pkinase PF00069.25 EEQ37290.1 - 1.8e-76 257.0 0.0 2.1e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37290.1 - 5.2e-37 127.5 0.0 6.7e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ37290.1 - 0.0011 18.0 0.0 0.009 15.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEQ37290.1 - 0.014 14.8 0.1 0.026 13.9 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ37290.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DisA-linker PF10635.9 EEQ37290.1 - 0.071 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Kinase-like PF14531.6 EEQ37290.1 - 0.17 11.2 0.1 0.34 10.2 0.1 1.6 1 1 0 1 1 1 0 Kinase-like AdoMet_MTase PF07757.13 EEQ37291.1 - 2e-40 137.6 0.0 3.3e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase CLTH PF10607.9 EEQ37292.1 - 3.3e-24 85.5 0.1 5.4e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain FlgN PF05130.12 EEQ37292.1 - 0.0042 17.6 2.0 0.027 15.0 0.4 2.3 2 0 0 2 2 2 1 FlgN protein PyrI_C PF02748.15 EEQ37292.1 - 0.13 12.2 0.3 0.27 11.2 0.3 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF1640 PF07798.11 EEQ37292.1 - 0.37 10.8 3.4 1 9.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Skp1_POZ PF03931.15 EEQ37293.1 - 5.8e-06 26.4 0.2 2e-05 24.7 0.2 1.8 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain Vps16_N PF04841.13 EEQ37294.1 - 1.4e-40 139.4 0.1 8.1e-31 107.2 0.0 3.3 2 1 0 2 2 2 2 Vps16, N-terminal region Vps16_C PF04840.12 EEQ37294.1 - 6.4e-38 130.6 17.4 1.7e-23 83.2 4.0 2.7 2 1 1 3 3 3 2 Vps16, C-terminal region DUF1281 PF06924.11 EEQ37294.1 - 0.2 11.2 2.6 0.42 10.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) CENP-N PF05238.13 EEQ37295.1 - 3e-102 343.0 0.0 3.4e-102 342.9 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like DUF5048 PF16467.5 EEQ37295.1 - 0.16 12.2 0.0 0.37 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5048) RRM_1 PF00076.22 EEQ37296.1 - 9.4e-56 185.6 0.1 3.4e-16 58.8 0.1 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ37296.1 - 2.3e-08 34.0 0.1 0.0098 16.0 0.0 3.9 4 0 0 4 4 4 2 RNA recognition motif CDC45 PF02724.14 EEQ37296.1 - 3.6e-05 22.3 11.7 3.6e-05 22.3 11.7 3.3 4 0 0 4 4 4 1 CDC45-like protein RRM_Rrp7 PF17799.1 EEQ37296.1 - 7.3e-05 22.6 0.2 0.11 12.3 0.0 3.8 4 0 0 4 4 4 2 Rrp7 RRM-like N-terminal domain PHM7_cyt PF14703.6 EEQ37296.1 - 0.00019 21.7 21.2 0.028 14.7 0.0 6.8 5 2 1 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 EEQ37296.1 - 0.012 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CNDH2_C PF16858.5 EEQ37296.1 - 8.2 6.2 38.2 0.033 14.1 13.1 2.7 2 1 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Metallophos PF00149.28 EEQ37298.1 - 6.9e-37 127.9 0.1 9e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEQ37298.1 - 0.051 14.0 0.2 0.11 12.9 0.2 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 EEQ37298.1 - 0.052 13.2 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain DUF5378 PF17349.2 EEQ37298.1 - 0.066 12.5 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Ribosomal_S18 PF01084.20 EEQ37299.1 - 7.3e-19 67.7 0.0 1.5e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 UQ_con PF00179.26 EEQ37300.1 - 1.7e-35 121.7 0.2 3.1e-35 120.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EB1 PF03271.17 EEQ37301.1 - 1.6e-14 53.8 0.4 3.1e-14 52.9 0.4 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EEQ37301.1 - 2.6e-07 30.8 0.0 4.8e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Remorin_C PF03763.13 EEQ37301.1 - 0.1 12.5 0.7 0.78 9.7 0.0 2.2 2 0 0 2 2 2 0 Remorin, C-terminal region CAMSAP_CH PF11971.8 EEQ37301.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain RAP1 PF07218.11 EEQ37301.1 - 3.2 5.9 4.4 3.5 5.8 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) zf-C2HE PF16278.5 EEQ37302.1 - 0.027 14.9 0.6 0.052 14.0 0.6 1.5 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger PET117 PF15786.5 EEQ37303.1 - 1.5e-25 89.3 0.4 1.7e-25 89.0 0.4 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial HTH_Tnp_IS630 PF01710.16 EEQ37303.1 - 0.026 14.6 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Transposase Trm5_N PF18093.1 EEQ37303.1 - 0.062 13.2 0.4 0.27 11.2 0.1 2.0 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain Cyclin PF08613.11 EEQ37304.1 - 5.7e-41 140.6 1.1 7.1e-41 140.3 0.0 1.8 2 1 0 2 2 2 1 Cyclin RTA1 PF04479.13 EEQ37306.1 - 4.7e-54 183.2 7.6 5.4e-54 183.0 7.6 1.0 1 0 0 1 1 1 1 RTA1 like protein Ribonuc_L-PSP PF01042.21 EEQ37308.1 - 9.4e-41 138.6 0.3 1.1e-40 138.4 0.3 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP TMEM135_C_rich PF15982.5 EEQ37310.1 - 9.5e-07 29.5 0.8 0.00017 22.2 0.1 2.6 2 0 0 2 2 2 2 N-terminal cysteine-rich region of Transmembrane protein 135 SRA1 PF07304.11 EEQ37311.1 - 2.3e-07 30.7 0.8 2.3e-07 30.7 0.8 4.6 4 2 0 4 4 4 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 EEQ37311.1 - 0.0044 17.8 8.7 13 6.8 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37311.1 - 0.035 14.4 0.2 1.4 9.3 0.4 2.9 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 EEQ37311.1 - 0.22 11.6 0.0 0.51 10.4 0.0 1.5 1 0 0 1 1 1 0 Prp18 domain Glyco_hydro_65m PF03632.15 EEQ37312.1 - 2.6e-37 128.6 3.1 7.3e-30 104.1 0.5 2.2 1 1 0 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 EEQ37312.1 - 3.6e-30 105.3 0.0 5.6e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF2152 PF10222.9 EEQ37312.1 - 0.093 11.0 0.0 0.23 9.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2152) DUF4834 PF16118.5 EEQ37312.1 - 0.24 12.4 1.3 0.3 12.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TCP PF03634.13 EEQ37312.1 - 0.37 11.3 4.6 6.5 7.3 2.8 2.8 2 1 0 2 2 2 0 TCP family transcription factor SpoIIIAH PF12685.7 EEQ37312.1 - 0.64 9.8 10.8 0.1 12.4 2.3 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein MIS13 PF08202.11 EEQ37313.1 - 9.5e-49 166.3 0.2 2e-48 165.3 0.0 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family RBR PF17208.3 EEQ37313.1 - 0.0036 18.0 4.4 0.0036 18.0 4.4 3.2 2 1 0 2 2 2 1 RNA binding Region FAM184 PF15665.5 EEQ37313.1 - 0.042 13.6 0.8 0.066 13.0 0.8 1.2 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B MRP-S33 PF08293.11 EEQ37315.1 - 9e-31 106.0 0.3 1e-30 105.8 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Ion_trans PF00520.31 EEQ37316.1 - 4e-109 363.6 109.8 4.2e-36 124.4 12.4 5.1 5 0 0 5 5 5 5 Ion transport protein GPHH PF16905.5 EEQ37316.1 - 0.0012 18.6 0.0 0.0032 17.2 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_1 PF00036.32 EEQ37316.1 - 0.061 12.9 0.0 0.23 11.1 0.0 2.1 1 0 0 1 1 1 0 EF hand CENP-O PF09496.10 EEQ37316.1 - 0.093 12.7 0.3 0.22 11.5 0.3 1.6 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component EF-hand_6 PF13405.6 EEQ37316.1 - 0.11 12.4 0.0 0.41 10.7 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 EEQ37316.1 - 0.11 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Lig_chan PF00060.26 EEQ37316.1 - 2.8 7.8 9.4 18 5.1 0.0 4.1 4 0 0 4 4 4 0 Ligand-gated ion channel zf-ZPR1 PF03367.13 EEQ37317.1 - 7.4e-119 393.2 0.2 1.3e-58 197.4 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EEQ37317.1 - 0.0024 17.9 3.0 1.1 9.3 0.1 2.5 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EEQ37317.1 - 0.026 14.5 6.6 1.6 8.8 1.7 3.3 3 0 0 3 3 3 0 Double zinc ribbon Cytochrom_C_2 PF01322.20 EEQ37317.1 - 0.087 13.7 3.3 5.5 7.9 0.2 3.5 4 0 0 4 4 4 0 Cytochrome C' zinc-ribbons_6 PF07191.12 EEQ37317.1 - 0.3 11.1 5.2 1.6 8.7 0.9 2.5 2 0 0 2 2 2 0 zinc-ribbons UPF0547 PF10571.9 EEQ37317.1 - 0.99 9.5 6.0 4.5 7.5 0.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 WD40 PF00400.32 EEQ37318.1 - 6.9e-39 131.1 30.8 1.5e-06 28.8 1.2 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.8 EEQ37318.1 - 2.7e-14 52.8 10.2 0.0011 17.7 0.7 5.7 3 1 2 6 6 6 4 Nucleoporin Nup120/160 F-box-like PF12937.7 EEQ37318.1 - 6.2e-14 51.6 0.9 1.4e-13 50.5 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ37318.1 - 2.1e-10 40.2 1.1 4.7e-10 39.1 0.5 2.0 2 0 0 2 2 2 1 F-box domain WD40_like PF17005.5 EEQ37318.1 - 3.3e-07 29.9 0.7 6.9e-06 25.6 0.3 2.3 2 1 0 2 2 2 1 WD40-like domain ANAPC4_WD40 PF12894.7 EEQ37318.1 - 2.7e-06 27.6 2.4 0.83 10.0 0.0 5.5 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EEQ37318.1 - 7.7e-06 25.9 0.0 0.057 13.5 0.0 3.8 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.11 EEQ37318.1 - 0.00035 20.5 0.5 2.1 8.2 0.0 3.3 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A F-box_4 PF15966.5 EEQ37318.1 - 0.0021 17.9 0.0 0.0083 16.0 0.0 2.1 1 0 0 1 1 1 1 F-box CDtoxinA PF03498.14 EEQ37318.1 - 0.04 13.5 2.6 1.7 8.2 0.4 3.7 3 1 1 4 4 4 0 Cytolethal distending toxin A/C domain PRANC PF09372.10 EEQ37318.1 - 0.063 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 PRANC domain CBM_21 PF03370.13 EEQ37319.1 - 9e-32 109.6 0.0 1.6e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EEQ37319.1 - 5.9e-07 30.0 0.1 1.5e-06 28.7 0.1 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) HTH_10 PF04967.12 EEQ37319.1 - 0.15 11.9 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 HTH DNA binding domain CorA PF01544.18 EEQ37320.1 - 3.3e-44 151.4 0.1 4.5e-44 150.9 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Tetraspanin PF00335.20 EEQ37320.1 - 0.0011 18.7 0.1 0.0039 16.9 0.2 1.7 2 0 0 2 2 2 1 Tetraspanin family DUF2207 PF09972.9 EEQ37320.1 - 0.056 12.2 0.2 0.085 11.6 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ac76 PF05814.11 EEQ37320.1 - 0.11 12.5 0.2 0.27 11.2 0.2 1.6 1 0 0 1 1 1 0 Orf76 (Ac76) DUF4282 PF14110.6 EEQ37320.1 - 0.14 12.9 3.2 0.27 12.0 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Spore_YhaL PF14147.6 EEQ37320.1 - 0.49 10.1 1.7 1.4 8.7 1.7 1.7 1 0 0 1 1 1 0 Sporulation protein YhaL LCM PF04072.14 EEQ37321.1 - 1.2e-18 67.7 0.0 1.9e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 EEQ37321.1 - 7.2e-15 54.7 0.2 6.6e-13 48.4 0.0 3.9 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EEQ37321.1 - 3.9e-10 39.7 3.4 4.6e-07 29.9 0.0 4.4 5 0 0 5 5 5 1 Kelch motif Kelch_5 PF13854.6 EEQ37321.1 - 1.6e-09 37.6 0.1 8.7e-05 22.4 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EEQ37321.1 - 4e-09 36.5 0.1 0.00047 20.4 0.0 3.8 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EEQ37321.1 - 2.9e-07 30.0 0.1 0.00046 19.7 0.0 4.6 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 EEQ37321.1 - 0.0015 18.4 0.3 0.088 12.8 0.0 3.3 4 0 0 4 4 4 1 Kelch motif KH_6 PF15985.5 EEQ37322.1 - 5.3e-15 55.5 1.3 6.9e-15 55.1 0.4 1.7 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 EEQ37322.1 - 5.5e-12 45.4 0.0 9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain FtsX_ECD PF18075.1 EEQ37322.1 - 0.022 15.4 0.2 0.044 14.4 0.2 1.5 1 0 0 1 1 1 0 FtsX extracellular domain AATase PF07247.12 EEQ37323.1 - 3.2e-44 151.3 0.0 5.3e-44 150.6 0.0 1.3 1 1 0 1 1 1 1 Alcohol acetyltransferase HLH PF00010.26 EEQ37324.1 - 3.8e-12 46.0 0.1 1e-11 44.6 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cullin_binding PF03556.15 EEQ37325.1 - 7.2e-29 100.7 1.8 1.3e-28 99.8 1.8 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EEQ37325.1 - 4.7e-11 42.3 0.1 8.5e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain MHB PF16525.5 EEQ37325.1 - 0.0012 19.1 0.1 0.0025 18.0 0.1 1.5 1 0 0 1 1 1 1 Haemophore, haem-binding Cullin PF00888.22 EEQ37326.1 - 6.9e-11 41.5 0.0 9.5e-11 41.0 0.0 1.1 1 0 0 1 1 1 1 Cullin family TFIID_20kDa PF03847.13 EEQ37327.1 - 8.9e-30 103.0 0.2 1.8e-29 102.0 0.2 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 EEQ37327.1 - 0.001 19.1 0.0 0.0023 18.0 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EEQ37327.1 - 0.008 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF5327 PF17261.2 EEQ37327.1 - 0.07 13.9 1.2 0.27 12.0 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5327) VasL PF12486.8 EEQ37327.1 - 1.4 8.8 6.8 3 7.7 0.6 2.5 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL OPT PF03169.15 EEQ37328.1 - 1.2e-120 404.1 25.0 1.5e-120 403.7 25.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Helicase_C PF00271.31 EEQ37329.1 - 2.7e-14 53.4 0.0 8.8e-14 51.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EEQ37329.1 - 1.1e-13 51.4 0.4 3.4e-13 49.8 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEQ37329.1 - 7.2e-13 48.7 0.1 5.2e-12 46.0 0.1 2.5 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EEQ37329.1 - 3.9e-09 36.5 1.2 9.6e-09 35.2 1.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.22 EEQ37329.1 - 2.5e-07 31.0 0.0 7.5e-07 29.4 0.0 1.9 1 0 0 1 1 1 1 RWD domain ResIII PF04851.15 EEQ37329.1 - 8.4e-07 29.1 0.4 1.9e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UBA PF00627.31 EEQ37329.1 - 1.1e-06 28.4 0.0 0.0065 16.4 0.0 3.1 3 0 0 3 3 3 2 UBA/TS-N domain AAA_29 PF13555.6 EEQ37329.1 - 0.00067 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EEQ37329.1 - 0.00087 19.6 0.1 0.0021 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEQ37329.1 - 0.0009 18.4 0.1 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 EEQ37329.1 - 0.0087 15.4 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 KaiC ABC_tran PF00005.27 EEQ37329.1 - 0.02 15.4 0.1 0.089 13.3 0.1 2.2 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 EEQ37329.1 - 0.035 13.6 0.0 0.093 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EEQ37329.1 - 0.047 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.6 EEQ37329.1 - 0.062 13.6 0.2 0.26 11.6 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ37329.1 - 0.073 13.1 0.8 3.9 7.5 0.8 3.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 EEQ37329.1 - 3 7.9 5.3 0.96 9.5 0.1 2.7 2 1 1 3 3 3 0 Helicase HerA, central domain AAA_23 PF13476.6 EEQ37329.1 - 9.3 6.7 10.4 0.29 11.6 1.8 2.9 3 1 0 3 3 3 0 AAA domain Complex1_49kDa PF00346.19 EEQ37330.1 - 1.1e-121 405.1 0.0 1.5e-121 404.7 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EEQ37330.1 - 0.012 14.5 0.0 0.027 13.4 0.0 1.6 1 0 0 1 1 1 0 Nickel-dependent hydrogenase DnaJ PF00226.31 EEQ37331.1 - 3.6e-16 59.0 2.6 7.4e-16 58.0 2.6 1.6 1 0 0 1 1 1 1 DnaJ domain ESCRT-II PF05871.12 EEQ37331.1 - 0.019 15.2 0.1 0.032 14.5 0.1 1.5 1 0 0 1 1 1 0 ESCRT-II complex subunit DUF2076 PF09849.9 EEQ37332.1 - 7.8e-07 29.4 6.7 8.3e-07 29.3 6.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EEQ37332.1 - 0.00093 19.3 4.7 0.0014 18.7 4.7 1.3 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 EEQ37332.1 - 0.061 13.6 2.5 0.12 12.6 2.5 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CX9C PF16860.5 EEQ37332.1 - 0.087 12.8 3.3 0.14 12.2 3.3 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, YbjQ_1 PF01906.17 EEQ37332.1 - 0.092 13.4 0.1 0.14 12.8 0.1 1.3 1 0 0 1 1 1 0 Putative heavy-metal-binding Na_K-ATPase PF00287.18 EEQ37332.1 - 0.34 10.0 4.3 0.43 9.7 4.3 1.1 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Nucleoporin_FG PF13634.6 EEQ37332.1 - 0.38 11.6 7.2 0.73 10.7 7.3 1.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region Sec-ASP3 PF15432.6 EEQ37334.1 - 0.012 15.8 0.1 0.02 15.0 0.1 1.4 1 0 0 1 1 1 0 Accessory Sec secretory system ASP3 LAP1C PF05609.12 EEQ37335.1 - 0.024 13.7 10.4 0.04 13.0 10.4 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Insulin_TMD PF17870.1 EEQ37335.1 - 0.23 11.6 0.0 0.52 10.4 0.0 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Nop14 PF04147.12 EEQ37335.1 - 0.42 8.8 17.1 0.57 8.3 17.1 1.1 1 0 0 1 1 1 0 Nop14-like family RAP1 PF07218.11 EEQ37335.1 - 0.45 8.7 15.2 0.86 7.8 15.2 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Raftlin PF15250.6 EEQ37335.1 - 0.8 8.4 10.3 1.2 7.9 10.3 1.2 1 0 0 1 1 1 0 Raftlin Tim54 PF11711.8 EEQ37335.1 - 1.5 7.5 8.0 2.3 6.9 8.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Topoisom_I PF01028.20 EEQ37336.1 - 5.4e-97 323.6 2.7 5.4e-97 323.6 2.7 2.6 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EEQ37336.1 - 1.2e-95 319.1 0.2 1.2e-95 319.1 0.2 3.2 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EEQ37336.1 - 3.8e-31 106.8 0.7 1.5e-30 104.9 0.7 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain PNK3P PF08645.11 EEQ37336.1 - 7.2 6.3 11.0 0.29 10.8 2.3 2.9 3 1 1 4 4 4 0 Polynucleotide kinase 3 phosphatase RNase_H PF00075.24 EEQ37337.1 - 1.6e-29 102.9 0.7 2.8e-29 102.1 0.7 1.4 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.16 EEQ37337.1 - 9.1e-20 70.7 4.0 2.7e-19 69.2 4.0 1.9 1 0 0 1 1 1 1 Caulimovirus viroplasmin CHB_HEX PF03173.13 EEQ37337.1 - 0.056 13.1 0.4 8.5 6.0 0.1 2.3 2 0 0 2 2 2 0 Putative carbohydrate binding domain GREB1 PF15782.5 EEQ37337.1 - 1.1 6.2 4.4 1.4 5.9 4.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 EEQ37338.1 - 4.3e-75 252.5 0.4 7.1e-75 251.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37338.1 - 1.1e-37 129.7 0.0 2.5e-37 128.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EEQ37338.1 - 6e-24 84.0 5.2 1.4e-13 50.8 0.0 3.1 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EEQ37338.1 - 6e-12 45.5 0.0 1.6e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ37338.1 - 0.0077 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ37338.1 - 0.044 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sin3a_C PF16879.5 EEQ37339.1 - 1.7e-82 277.4 5.6 1.7e-82 277.4 5.6 3.7 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 EEQ37339.1 - 9.2e-50 166.6 14.3 3.2e-18 65.6 2.1 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EEQ37339.1 - 3.1e-42 142.6 0.8 2.4e-41 139.7 0.1 2.7 2 0 0 2 2 2 1 Sin3 family co-repressor Dna2 PF08696.11 EEQ37339.1 - 0.066 13.0 0.5 19 5.0 0.1 2.9 2 0 0 2 2 2 0 DNA replication factor Dna2 Membr_traf_MHD PF10540.9 EEQ37340.1 - 3e-43 147.5 0.1 9.5e-43 145.9 0.1 1.9 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EEQ37340.1 - 4.1e-10 39.9 0.0 8.7e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 EEQ37340.1 - 3e-06 26.1 0.2 3.5e-05 22.6 0.2 2.2 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) DnaB_2 PF07261.11 EEQ37340.1 - 0.1 12.3 0.1 1 9.2 0.0 2.6 3 0 0 3 3 3 0 Replication initiation and membrane attachment DUF4441 PF14536.6 EEQ37340.1 - 0.4 10.9 5.4 3.3 8.0 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) SWIB PF02201.18 EEQ37341.1 - 3.3e-31 107.0 0.0 6.7e-31 106.0 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Astro_capsid_p PF12226.8 EEQ37341.1 - 0.14 11.3 4.3 0.24 10.5 4.3 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RRS1 PF04939.12 EEQ37342.1 - 1.2e-58 197.5 4.4 1.4e-58 197.3 4.4 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) EF_assoc_1 PF08355.12 EEQ37343.1 - 4e-29 100.0 0.1 6.3e-29 99.4 0.1 1.3 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 EEQ37343.1 - 2.8e-25 88.1 0.0 6e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EEQ37343.1 - 1.4e-11 44.3 0.0 2.1e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ37343.1 - 0.00019 21.6 0.0 0.00054 20.2 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_5 PF13202.6 EEQ37343.1 - 0.0022 17.4 2.2 0.0049 16.3 2.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EEQ37343.1 - 0.0027 17.1 1.7 0.0065 15.9 1.7 1.7 1 0 0 1 1 1 1 EF hand Arf PF00025.21 EEQ37343.1 - 0.0092 15.4 0.0 0.018 14.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family EF-hand_6 PF13405.6 EEQ37343.1 - 0.014 15.2 0.8 0.041 13.8 0.8 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_8 PF13833.6 EEQ37343.1 - 0.15 11.9 0.9 0.4 10.6 0.9 1.7 1 0 0 1 1 1 0 EF-hand domain pair FtsK_SpoIIIE PF01580.18 EEQ37343.1 - 0.21 10.9 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family BolA PF01722.18 EEQ37344.1 - 3.3e-13 49.7 0.0 7.5e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein DUF3780 PF12635.7 EEQ37345.1 - 0.099 12.4 0.0 9.2 6.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3780) eIF2A PF08662.11 EEQ37346.1 - 3.3e-22 79.3 0.1 5.7e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EEQ37346.1 - 0.18 11.8 1.9 13 5.9 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RRM_1 PF00076.22 EEQ37347.1 - 2.1e-05 24.3 0.0 4.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF2A PF08662.11 EEQ37347.1 - 0.16 11.8 0.0 0.64 9.9 0.0 1.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A NPV_P10 PF05531.12 EEQ37348.1 - 0.00021 21.7 2.0 0.4 11.2 0.4 3.8 2 1 1 3 3 3 1 Nucleopolyhedrovirus P10 protein HALZ PF02183.18 EEQ37348.1 - 0.013 15.7 0.6 0.013 15.7 0.6 5.6 5 1 1 6 6 6 0 Homeobox associated leucine zipper Baculo_PEP_C PF04513.12 EEQ37348.1 - 0.083 12.9 9.2 1.2 9.2 0.9 3.7 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 EEQ37348.1 - 0.13 12.7 9.8 0.62 10.5 0.3 4.4 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) LPP PF04728.13 EEQ37348.1 - 0.27 11.7 5.8 0.63 10.5 0.5 3.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper KMP11 PF03037.16 EEQ37348.1 - 0.33 11.7 6.3 0.7 10.7 0.1 3.3 2 1 1 3 3 3 0 Kinetoplastid membrane protein 11 GP41 PF00517.17 EEQ37348.1 - 0.42 10.5 5.1 2.6 7.9 0.1 2.6 2 0 0 2 2 2 0 Retroviral envelope protein GAS PF13851.6 EEQ37348.1 - 0.61 9.4 34.1 0.068 12.5 13.0 3.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding PilJ PF13675.6 EEQ37348.1 - 0.86 9.7 8.0 5.8 7.0 0.1 3.7 1 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term SlyX PF04102.12 EEQ37348.1 - 0.93 10.2 0.1 0.93 10.2 0.1 4.6 2 1 3 5 5 5 0 SlyX DUF1664 PF07889.12 EEQ37348.1 - 3.2 7.8 12.9 0.49 10.5 2.7 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) YgaB PF14182.6 EEQ37348.1 - 8.8 6.8 19.7 1.2 9.6 0.2 4.9 3 1 1 5 5 5 0 YgaB-like protein Pox_A_type_inc PF04508.12 EEQ37349.1 - 0.072 13.0 0.9 0.14 12.0 0.3 1.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Exo5 PF09810.9 EEQ37349.1 - 0.2 11.1 7.2 0.021 14.4 2.0 2.0 1 1 1 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Proteasome PF00227.26 EEQ37350.1 - 5.9e-53 179.2 0.0 7.2e-53 178.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DHHC PF01529.20 EEQ37351.1 - 6.9e-34 116.8 7.6 6.9e-34 116.8 7.6 1.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase PocR PF10114.9 EEQ37351.1 - 1.7 8.4 4.3 2.9 7.6 4.3 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR AhpC-TSA PF00578.21 EEQ37352.1 - 1e-33 115.9 0.0 1.4e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEQ37352.1 - 1.5e-14 54.0 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EEQ37352.1 - 1.2e-12 47.5 0.1 1.9e-12 46.8 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MMU163 PF17119.5 EEQ37353.1 - 6.4e-18 64.8 0.1 1.1e-17 64.0 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis AKNA PF12443.8 EEQ37353.1 - 0.33 11.6 0.1 0.33 11.6 0.1 1.7 2 0 0 2 2 2 0 AT-hook-containing transcription factor VASt PF16016.5 EEQ37354.1 - 5.4e-34 117.8 0.0 1.3e-33 116.6 0.0 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EEQ37354.1 - 7.5e-27 93.5 0.1 1.4e-26 92.6 0.1 1.5 1 0 0 1 1 1 1 GRAM domain PHP_C PF13263.6 EEQ37354.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 PHP-associated Ribosomal_S3Ae PF01015.18 EEQ37355.1 - 2.4e-85 285.2 3.3 2.8e-85 285.0 3.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EEQ37355.1 - 0.051 14.1 1.0 0.12 12.9 0.1 2.1 2 0 0 2 2 2 0 Translation initiation factor SUI1 SpoVIF PF14069.6 EEQ37355.1 - 0.093 12.5 4.5 2.8 7.8 1.4 2.6 2 0 0 2 2 2 0 Stage VI sporulation protein F Abhydro_lipase PF04083.16 EEQ37355.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region IlvN PF07991.12 EEQ37356.1 - 8e-44 149.1 0.0 1.3e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EEQ37356.1 - 8.8e-43 146.0 0.1 3.1e-42 144.3 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain TatD_DNase PF01026.21 EEQ37356.1 - 0.18 11.2 0.0 0.5 9.7 0.0 1.7 2 0 0 2 2 2 0 TatD related DNase Pkinase PF00069.25 EEQ37357.1 - 2.9e-48 164.5 0.1 3.9e-48 164.1 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37357.1 - 4.4e-30 104.8 0.1 5.2e-29 101.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EEQ37357.1 - 0.00033 20.6 0.2 0.00061 19.8 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ37357.1 - 0.0067 15.8 0.0 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEQ37357.1 - 0.018 14.0 0.1 0.04 12.9 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Nop10p PF04135.12 EEQ37358.1 - 3e-21 75.2 0.2 3.3e-21 75.0 0.2 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family TPR_12 PF13424.6 EEQ37359.1 - 7.1e-08 32.6 0.1 6.5e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ37359.1 - 1.6e-07 30.9 0.1 0.045 13.9 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ37359.1 - 3.1e-06 26.7 0.1 0.14 12.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat MIT PF04212.18 EEQ37359.1 - 0.00018 21.5 0.1 0.5 10.5 0.0 2.9 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain RNA_GG_bind PF10258.9 EEQ37359.1 - 0.0011 19.0 0.1 1 9.5 0.2 2.9 2 1 0 2 2 2 2 PHAX RNA-binding domain TPR_19 PF14559.6 EEQ37359.1 - 0.01 16.3 0.2 0.054 14.0 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ37359.1 - 0.028 14.6 0.6 6.7 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ37359.1 - 0.048 13.5 0.2 3 7.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 EEQ37359.1 - 0.14 12.3 0.7 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 DnaJ domain DUF2406 PF10295.9 EEQ37360.1 - 2.5e-27 95.3 1.2 8.4e-27 93.6 0.5 2.1 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Pkinase PF00069.25 EEQ37361.1 - 1.7e-70 237.4 0.0 2.1e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37361.1 - 3e-35 121.8 0.0 4e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ37361.1 - 4.9e-05 22.4 0.4 7.7e-05 21.8 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEQ37361.1 - 0.00041 19.8 0.1 0.00062 19.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ37361.1 - 0.0057 16.0 0.1 0.011 15.0 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EEQ37361.1 - 0.021 13.9 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EEQ37361.1 - 0.023 14.4 0.2 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEQ37361.1 - 0.023 14.7 0.2 0.075 12.9 0.3 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEQ37361.1 - 0.075 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase EMP24_GP25L PF01105.24 EEQ37362.1 - 1.3e-45 155.6 0.5 1.5e-45 155.4 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pox_EPC_I2-L1 PF12575.8 EEQ37362.1 - 0.069 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Lsr2 PF11774.8 EEQ37362.1 - 0.11 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Lsr2 Aminotran_1_2 PF00155.21 EEQ37363.1 - 3.4e-75 253.5 0.0 3.9e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_S27e PF01667.17 EEQ37364.1 - 5e-26 90.2 5.8 5.4e-26 90.1 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S27 zinc_ribbon_4 PF13717.6 EEQ37364.1 - 0.089 12.7 3.2 5.1 7.1 3.2 2.5 1 1 0 1 1 1 0 zinc-ribbon domain Metallophos PF00149.28 EEQ37365.1 - 1.2e-40 140.2 0.1 1.6e-40 139.8 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEQ37365.1 - 4e-22 78.4 1.1 6.7e-22 77.7 0.6 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Vfa1 PF08432.10 EEQ37366.1 - 1.7e-44 152.3 10.5 1.9e-44 152.2 10.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 ATG16 PF08614.11 EEQ37366.1 - 0.0013 19.0 2.1 0.0018 18.5 2.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 EEQ37366.1 - 0.011 14.8 2.0 0.015 14.4 2.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5523 PF17661.1 EEQ37366.1 - 0.023 14.4 4.3 0.032 13.9 4.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) DivIVA PF05103.13 EEQ37366.1 - 0.053 13.6 3.3 0.41 10.7 0.5 2.2 2 0 0 2 2 2 0 DivIVA protein FapA PF03961.13 EEQ37366.1 - 0.26 9.8 2.4 0.32 9.6 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SRPRB PF09439.10 EEQ37367.1 - 3e-31 108.2 0.0 3.9e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EEQ37367.1 - 2.6e-08 33.5 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ37367.1 - 0.00026 20.6 0.0 0.0006 19.4 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEQ37367.1 - 0.00033 20.7 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EEQ37367.1 - 0.00042 20.2 0.2 0.0042 16.9 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EEQ37367.1 - 0.09 12.7 0.1 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 EEQ37367.1 - 0.85 10.1 6.3 5.5 7.4 6.3 2.1 1 1 0 1 1 1 0 AAA domain Chorismate_synt PF01264.21 EEQ37368.1 - 6e-142 472.2 0.0 6.8e-142 472.0 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_3 PF13415.6 EEQ37369.1 - 1e-05 25.7 0.6 0.038 14.3 0.0 4.0 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 EEQ37369.1 - 0.0014 18.6 0.3 0.15 12.1 0.0 3.3 3 0 0 3 3 3 1 Galactose oxidase, central domain zf-C2H2 PF00096.26 EEQ37370.1 - 6.7e-12 45.2 12.4 1.6e-05 25.1 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ37370.1 - 4.1e-10 39.6 13.5 4.6e-08 33.1 4.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ37370.1 - 1.1e-08 35.2 11.6 0.00032 21.3 0.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ37370.1 - 5.2e-06 26.6 5.5 0.036 14.3 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EEQ37370.1 - 1.2e-05 25.4 3.1 2.1e-05 24.7 3.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 EEQ37370.1 - 4.7e-05 23.3 8.7 0.00034 20.5 0.6 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 EEQ37370.1 - 8.3e-05 22.8 6.2 0.0088 16.4 0.7 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-BED PF02892.15 EEQ37370.1 - 0.00073 19.5 6.8 0.024 14.6 2.0 2.5 1 1 1 2 2 2 2 BED zinc finger GAGA PF09237.11 EEQ37370.1 - 0.0086 15.9 1.6 0.0086 15.9 1.6 2.1 2 0 0 2 2 1 1 GAGA factor zf-C2H2_9 PF16293.5 EEQ37370.1 - 0.022 14.6 0.3 0.22 11.4 0.1 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (1 copy) DUF2225 PF09986.9 EEQ37370.1 - 0.064 13.0 4.0 0.19 11.4 0.5 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DZR PF12773.7 EEQ37370.1 - 0.14 12.2 0.7 0.28 11.2 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-MYST PF17772.1 EEQ37370.1 - 0.17 11.5 2.8 0.22 11.1 0.6 2.2 1 1 1 2 2 2 0 MYST family zinc finger domain Prok-RING_4 PF14447.6 EEQ37370.1 - 0.27 11.1 0.9 0.71 9.8 0.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-CHCC PF10276.9 EEQ37370.1 - 0.43 10.7 2.8 0.45 10.6 0.4 2.1 2 0 0 2 2 2 0 Zinc-finger domain Zn-ribbon_8 PF09723.10 EEQ37370.1 - 0.55 10.4 2.4 1.3 9.2 2.4 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 EEQ37370.1 - 0.62 10.4 10.4 1.7 9.0 0.6 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 EEQ37370.1 - 2.5 8.1 6.3 5.2 7.1 6.3 1.5 1 0 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 EEQ37370.1 - 3.1 7.8 7.5 14 5.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PyrI_C PF02748.15 EEQ37370.1 - 4.7 7.2 5.5 9.5 6.2 0.7 2.6 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 PF00096.26 EEQ37371.1 - 9.2e-12 44.7 20.6 7.5e-06 26.1 3.5 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ37371.1 - 4.5e-08 33.3 15.8 0.00039 21.0 2.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEQ37371.1 - 1e-05 25.7 14.4 3.2e-05 24.2 0.4 4.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EEQ37371.1 - 0.0045 17.2 1.6 0.0045 17.2 1.6 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EEQ37371.1 - 0.0098 15.9 1.1 0.0098 15.9 1.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger C5HCH PF17982.1 EEQ37371.1 - 0.15 12.3 2.6 0.35 11.1 2.6 1.6 1 0 0 1 1 1 0 NSD Cys-His rich domain zf-TRAF PF02176.18 EEQ37371.1 - 0.65 10.7 7.7 0.059 14.1 2.1 2.1 1 1 1 2 2 2 0 TRAF-type zinc finger zf-C2HE PF16278.5 EEQ37371.1 - 3.2 8.3 6.6 0.62 10.6 0.6 2.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger 2-oxoacid_dh PF00198.23 EEQ37372.1 - 1.5e-80 270.0 0.1 2.8e-80 269.1 0.1 1.5 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EEQ37372.1 - 4.9e-18 64.7 4.6 1e-17 63.7 4.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EEQ37372.1 - 0.00028 20.6 1.3 0.0011 18.8 0.4 2.1 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 EEQ37372.1 - 0.00029 20.7 2.0 0.00092 19.1 1.8 2.0 2 0 0 2 2 1 1 Glycine cleavage H-protein TraF PF13728.6 EEQ37372.1 - 0.0012 18.7 10.8 0.0012 18.7 10.8 1.6 2 0 0 2 2 1 1 F plasmid transfer operon protein HlyD_3 PF13437.6 EEQ37372.1 - 0.0018 18.9 1.9 0.056 14.1 0.4 2.5 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 EEQ37372.1 - 0.0046 16.9 0.8 0.23 11.4 0.0 2.7 1 1 1 2 2 2 1 RnfC Barrel sandwich hybrid domain RNA_pol_Rpc4 PF05132.14 EEQ37372.1 - 0.037 14.5 8.0 0.062 13.7 8.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 RR_TM4-6 PF06459.12 EEQ37372.1 - 0.066 13.0 12.9 0.087 12.6 12.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CPSF100_C PF13299.6 EEQ37372.1 - 0.15 12.2 9.3 0.25 11.5 8.2 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Asp-B-Hydro_N PF05279.11 EEQ37372.1 - 0.25 11.4 17.8 0.34 10.9 17.8 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2052 PF09747.9 EEQ37372.1 - 0.26 11.4 12.8 0.39 10.8 12.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 EEQ37372.1 - 0.36 9.5 11.0 0.57 8.9 11.0 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EEQ37372.1 - 0.52 10.3 3.7 0.68 10.0 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vfa1 PF08432.10 EEQ37372.1 - 0.52 10.6 18.6 0.85 9.9 18.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RP-C_C PF11800.8 EEQ37372.1 - 0.88 9.6 9.1 0.98 9.5 7.1 2.0 2 0 0 2 2 2 0 Replication protein C C-terminal region Ndc1_Nup PF09531.10 EEQ37372.1 - 0.97 8.0 6.7 1.3 7.6 6.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC45 PF02724.14 EEQ37372.1 - 1.7 6.8 13.9 2.3 6.4 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM163 PF15069.6 EEQ37372.1 - 1.8 9.0 5.4 4.2 7.8 5.4 1.6 1 0 0 1 1 1 0 FAM163 family Coilin_N PF15862.5 EEQ37372.1 - 1.8 8.3 12.7 3 7.6 11.8 1.9 2 0 0 2 2 2 0 Coilin N-terminus Tim54 PF11711.8 EEQ37372.1 - 2.8 6.6 14.6 4.7 5.9 14.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 NPR3 PF03666.13 EEQ37372.1 - 3.4 6.3 14.7 5 5.8 14.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 EEQ37372.1 - 4.2 7.1 7.7 6.1 6.5 7.7 1.3 1 0 0 1 1 1 0 Connexin SpoIIP PF07454.11 EEQ37372.1 - 4.6 6.6 13.2 9.3 5.6 12.7 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DDRGK PF09756.9 EEQ37372.1 - 7.2 6.2 21.5 12 5.4 21.5 1.3 1 0 0 1 1 1 0 DDRGK domain ALMT PF11744.8 EEQ37372.1 - 8.1 5.2 8.2 11 4.7 8.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 EEQ37372.1 - 8.2 5.3 11.5 14 4.6 11.5 1.3 1 0 0 1 1 1 0 Solute carrier family 12 AAA PF00004.29 EEQ37373.1 - 0.11 12.9 0.2 0.46 10.9 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TRP PF06011.12 EEQ37374.1 - 2.1e-153 511.1 32.4 2.5e-153 510.8 32.4 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel PI3_PI4_kinase PF00454.27 EEQ37375.1 - 3.1e-43 148.4 0.0 9.3e-31 107.5 0.0 2.4 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EEQ37375.1 - 6.6e-24 84.3 0.0 1.3e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) eIF-6 PF01912.18 EEQ37377.1 - 5.9e-83 277.1 0.5 7.4e-83 276.8 0.5 1.1 1 0 0 1 1 1 1 eIF-6 family AAA_2 PF07724.14 EEQ37378.1 - 9.5e-48 162.5 1.0 2.7e-45 154.5 0.0 3.5 4 0 0 4 4 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EEQ37378.1 - 9.5e-31 105.8 6.0 1.3e-30 105.4 1.3 2.8 2 0 0 2 2 2 1 AAA lid domain AAA PF00004.29 EEQ37378.1 - 4.4e-23 82.1 0.1 4.6e-12 46.5 0.1 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EEQ37378.1 - 5.2e-23 80.9 0.3 3.8e-22 78.2 0.8 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EEQ37378.1 - 2.7e-14 53.3 0.0 1.8e-08 34.5 0.0 3.3 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EEQ37378.1 - 5e-13 49.1 0.2 9.3e-07 28.7 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.20 EEQ37378.1 - 5.4e-11 42.4 1.7 4.4e-08 33.1 0.2 3.5 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 EEQ37378.1 - 1.9e-10 41.4 9.1 7.4e-06 26.4 0.3 4.5 3 2 2 5 5 4 2 AAA ATPase domain AAA_22 PF13401.6 EEQ37378.1 - 9.4e-07 29.2 2.3 0.25 11.6 0.0 4.8 3 2 0 3 3 2 2 AAA domain AAA_14 PF13173.6 EEQ37378.1 - 5.1e-06 26.5 0.0 0.14 12.2 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 EEQ37378.1 - 2.3e-05 24.0 0.0 0.0088 15.6 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region TniB PF05621.11 EEQ37378.1 - 4.1e-05 23.1 0.2 0.046 13.1 0.0 4.0 3 2 0 3 3 3 1 Bacterial TniB protein ATPase_2 PF01637.18 EEQ37378.1 - 0.00019 21.4 8.7 0.086 12.7 0.2 4.6 4 1 1 5 5 3 2 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EEQ37378.1 - 0.00022 21.2 0.1 0.069 13.1 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase Mg_chelatase PF01078.21 EEQ37378.1 - 0.00026 20.5 0.1 3 7.2 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EEQ37378.1 - 0.00034 20.6 0.7 0.091 12.7 0.0 3.1 3 0 0 3 3 2 1 NACHT domain AAA_30 PF13604.6 EEQ37378.1 - 0.0005 19.8 0.1 0.022 14.5 0.1 2.8 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EEQ37378.1 - 0.0036 17.3 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EEQ37378.1 - 0.0038 17.4 0.1 0.42 10.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EEQ37378.1 - 0.0041 17.3 0.3 0.69 10.1 0.0 2.9 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_3 PF07726.11 EEQ37378.1 - 0.0083 16.0 0.0 0.21 11.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EEQ37378.1 - 0.017 14.4 0.5 0.34 10.2 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.6 EEQ37378.1 - 0.019 14.7 0.0 7.2 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EEQ37378.1 - 0.024 14.4 0.1 1.6 8.5 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_8 PF12780.7 EEQ37378.1 - 0.025 13.9 0.8 0.83 8.9 0.5 2.9 2 1 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_29 PF13555.6 EEQ37378.1 - 0.026 14.2 0.2 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EEQ37378.1 - 0.04 14.4 0.1 16 6.0 0.0 3.1 2 0 0 2 2 2 0 ABC transporter PEPCK_ATP PF01293.20 EEQ37378.1 - 0.043 12.5 0.0 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase APS_kinase PF01583.20 EEQ37378.1 - 0.05 13.5 0.6 0.32 10.9 0.0 2.6 3 1 1 4 4 2 0 Adenylylsulphate kinase DUF815 PF05673.13 EEQ37378.1 - 0.053 12.7 1.6 1 8.5 0.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EEQ37378.1 - 0.059 13.9 1.1 11 6.6 0.3 3.8 3 1 0 3 3 2 0 AAA domain AAA_19 PF13245.6 EEQ37378.1 - 0.075 13.4 2.5 2.6 8.4 0.1 3.8 2 2 1 3 3 3 0 AAA domain Nup54 PF13874.6 EEQ37378.1 - 0.076 13.1 6.7 0.27 11.3 6.7 1.9 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 NB-ARC PF00931.22 EEQ37378.1 - 0.078 12.2 0.1 2.6 7.2 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain SRP54 PF00448.22 EEQ37378.1 - 0.09 12.4 2.1 2.3 7.8 0.0 3.3 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain Torsin PF06309.11 EEQ37378.1 - 0.13 12.4 0.0 0.61 10.2 0.0 2.1 2 0 0 2 2 1 0 Torsin V_ATPase_I PF01496.19 EEQ37378.1 - 0.3 8.9 4.2 0.5 8.2 4.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.12 EEQ37378.1 - 2.1 9.0 11.3 2.5 8.8 0.1 3.9 2 1 1 3 3 3 0 SlyX FlaC_arch PF05377.11 EEQ37378.1 - 5 7.6 5.2 7.5 7.0 2.0 2.8 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ArfGap PF01412.18 EEQ37379.1 - 7.1e-29 100.3 0.0 7.1e-29 100.3 0.0 2.0 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.31 EEQ37379.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Endostatin PF06482.11 EEQ37379.1 - 0.26 10.7 13.4 0.49 9.8 13.4 1.4 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Fer4_6 PF12837.7 EEQ37379.1 - 6.8 6.9 6.6 4.6 7.5 2.0 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain HVSL PF09749.9 EEQ37380.1 - 0.0045 16.5 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein Amelogenin PF02948.15 EEQ37380.1 - 0.024 15.3 1.4 0.042 14.5 1.4 1.3 1 0 0 1 1 1 0 Amelogenin TP2 PF01254.18 EEQ37380.1 - 0.039 14.6 2.4 0.098 13.3 2.4 1.6 1 0 0 1 1 1 0 Nuclear transition protein 2 Sugar_tr PF00083.24 EEQ37381.1 - 5.4e-117 391.4 23.7 6.3e-117 391.2 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ37381.1 - 1.3e-24 86.8 28.1 1.3e-24 86.8 28.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily GMC_oxred_N PF00732.19 EEQ37382.1 - 1e-57 195.8 0.4 1.5e-57 195.3 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EEQ37382.1 - 3.7e-22 79.4 1.3 7.3e-22 78.4 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EEQ37382.1 - 1.7e-07 30.7 0.1 0.0044 16.2 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EEQ37382.1 - 0.0043 17.2 0.6 0.013 15.7 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EEQ37382.1 - 0.12 11.7 0.1 0.25 10.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 EEQ37382.1 - 0.12 11.6 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mss4 PF04421.13 EEQ37383.1 - 1.1e-15 57.5 0.0 1.3e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Mss4 protein DUF1518 PF07469.12 EEQ37384.1 - 0.58 10.6 6.0 1.8 9.0 6.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1518) FBA_2 PF07735.17 EEQ37384.1 - 1.2 9.4 7.5 3.4 7.9 1.9 3.2 3 0 0 3 3 3 0 F-box associated Aminotran_1_2 PF00155.21 EEQ37385.1 - 8.3e-38 130.5 0.0 1.1e-37 130.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF4250 PF14056.6 EEQ37385.1 - 0.89 9.5 0.0 0.89 9.5 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Patatin PF01734.22 EEQ37386.1 - 1.4e-21 77.6 0.1 3.6e-21 76.3 0.1 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 EEQ37386.1 - 1e-20 73.6 0.1 1.9e-11 43.9 0.0 4.8 4 1 0 4 4 4 2 Cyclic nucleotide-binding domain tRNA_synt_1c_R1 PF04558.15 EEQ37386.1 - 0.053 13.5 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 ATPase PF06745.13 EEQ37386.1 - 0.093 12.1 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 KaiC UvrD_C_2 PF13538.6 EEQ37387.1 - 2.8e-05 23.9 0.3 0.0031 17.3 0.3 2.6 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 EEQ37387.1 - 8.4e-05 20.7 0.0 0.00011 20.3 0.0 1.2 1 0 0 1 1 1 1 Helicase Phage_DNA_bind PF02303.17 EEQ37387.1 - 0.01 16.1 0.5 0.039 14.2 0.2 1.9 2 0 0 2 2 2 0 Helix-destabilising protein PIF1 PF05970.14 EEQ37388.1 - 1.2e-30 106.9 0.0 5.9e-26 91.5 0.0 2.0 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EEQ37388.1 - 5.2e-08 32.8 0.0 5.3e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ37388.1 - 0.01 16.2 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Sec39 PF08314.11 EEQ37389.1 - 3.3e-50 171.4 18.3 5e-50 170.8 18.3 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 DUF5624 PF18538.1 EEQ37390.1 - 0.13 12.3 0.4 4.9 7.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) HisKA_2 PF07568.12 EEQ37390.1 - 0.23 11.6 1.5 34 4.6 0.2 3.2 2 1 0 2 2 2 0 Histidine kinase CHDCT2 PF08074.11 EEQ37390.1 - 1.9 8.6 4.8 0.72 10.0 0.8 2.0 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Prominin PF05478.11 EEQ37390.1 - 4.1 5.2 7.2 1.7 6.5 2.4 2.2 2 1 0 2 2 2 0 Prominin LSM PF01423.22 EEQ37391.1 - 1.7e-18 66.1 0.1 2.8e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 LSM domain MRP-L47 PF06984.13 EEQ37392.1 - 2.5e-15 56.4 0.1 4.9e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Glutaredoxin2_C PF04399.13 EEQ37392.1 - 0.0023 17.7 0.9 2.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Glutaredoxin 2, C terminal domain DUF4461 PF14688.6 EEQ37392.1 - 0.013 15.4 0.2 0.021 14.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) AIM5 PF17050.5 EEQ37393.1 - 2.4e-13 50.7 3.5 3.1e-13 50.3 3.5 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 adh_short PF00106.25 EEQ37394.1 - 3.7e-23 82.0 0.0 5.4e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ37394.1 - 6.1e-18 65.2 0.0 8.6e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ37394.1 - 2.7e-07 30.7 0.2 9.5e-07 28.9 0.2 1.7 1 1 0 1 1 1 1 KR domain DUF3104 PF11302.8 EEQ37394.1 - 0.0084 15.8 0.1 0.02 14.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3104) THF_DHG_CYH_C PF02882.19 EEQ37394.1 - 0.016 14.5 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 EEQ37394.1 - 0.042 13.2 0.0 0.088 12.2 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EEQ37394.1 - 0.16 11.4 0.2 0.62 9.5 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L17 PF01196.19 EEQ37395.1 - 4e-22 78.9 0.2 6.2e-22 78.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 Mrpl_C PF18502.1 EEQ37395.1 - 0.015 15.5 0.2 0.089 13.1 0.0 2.0 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain DUF3365 PF11845.8 EEQ37395.1 - 0.14 12.5 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) TMA7 PF09072.10 EEQ37396.1 - 1.8e-26 92.8 22.7 2e-26 92.6 22.7 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 cobW PF02492.19 EEQ37397.1 - 8.9e-47 158.9 5.5 1.3e-44 151.8 5.5 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EEQ37397.1 - 1e-19 70.2 0.0 4.7e-15 55.3 0.0 2.4 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain CDC45 PF02724.14 EEQ37397.1 - 0.0026 16.2 9.0 0.012 13.9 8.8 1.9 2 0 0 2 2 2 1 CDC45-like protein MobB PF03205.14 EEQ37397.1 - 0.0057 16.6 0.1 0.012 15.5 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 EEQ37397.1 - 0.0073 15.3 0.2 0.069 12.1 0.2 2.5 1 1 1 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GEMIN8 PF15348.6 EEQ37397.1 - 0.021 15.1 1.9 0.034 14.5 1.9 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 AAA_33 PF13671.6 EEQ37397.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ37397.1 - 0.026 15.1 0.0 0.026 15.1 0.0 2.2 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.6 EEQ37397.1 - 0.027 14.9 0.3 0.062 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain BUD22 PF09073.10 EEQ37397.1 - 0.028 13.8 8.8 0.041 13.2 8.8 1.1 1 0 0 1 1 1 0 BUD22 TFIIA PF03153.13 EEQ37397.1 - 0.055 13.5 8.6 0.074 13.0 8.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Viral_helicase1 PF01443.18 EEQ37397.1 - 0.065 13.0 0.2 0.23 11.2 0.0 2.0 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 EEQ37397.1 - 0.13 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Astro_capsid_p PF12226.8 EEQ37397.1 - 0.14 11.3 10.7 0.21 10.7 10.7 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein RNA_pol_3_Rpc31 PF11705.8 EEQ37397.1 - 0.16 12.2 12.5 0.3 11.3 12.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 EEQ37397.1 - 0.27 9.3 18.9 0.43 8.6 18.9 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EEQ37397.1 - 0.28 10.4 13.1 0.42 9.9 13.1 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 EEQ37397.1 - 0.31 11.4 7.1 0.74 10.2 7.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 EEQ37397.1 - 0.38 8.9 13.9 0.52 8.5 13.9 1.1 1 0 0 1 1 1 0 Nop14-like family MCRS_N PF13325.6 EEQ37397.1 - 0.51 10.3 8.6 0.62 10.0 1.5 2.5 2 1 1 3 3 2 0 N-terminal region of micro-spherule protein AAA_14 PF13173.6 EEQ37397.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.1 4 0 0 4 4 4 0 AAA domain FAM176 PF14851.6 EEQ37397.1 - 1.3 8.7 8.0 2.6 7.7 8.0 1.4 1 0 0 1 1 1 0 FAM176 family DUF3381 PF11861.8 EEQ37397.1 - 1.5 8.6 11.5 6.9 6.5 9.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) SDA1 PF05285.12 EEQ37397.1 - 3.7 6.9 16.3 7.5 5.9 16.3 1.4 1 0 0 1 1 1 0 SDA1 WH1 PF00568.23 EEQ37398.1 - 2.9e-27 94.8 0.0 2.9e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 WH1 domain WH2 PF02205.20 EEQ37398.1 - 6.5e-06 25.8 0.4 1.3e-05 24.8 0.4 1.6 1 0 0 1 1 1 1 WH2 motif GCIP PF13324.6 EEQ37399.1 - 4.3e-20 72.4 7.4 6.1e-20 71.9 7.3 1.4 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 EEQ37399.1 - 4 7.9 7.1 0.87 10.0 3.5 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Esterase PF00756.20 EEQ37400.1 - 4.3e-54 183.8 0.0 5.1e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EEQ37400.1 - 1.9e-06 27.6 0.2 2.8e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EEQ37400.1 - 1.1e-05 24.6 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EEQ37400.1 - 0.00046 19.5 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 EEQ37400.1 - 0.00084 18.1 0.0 0.0013 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.11 EEQ37400.1 - 0.0018 17.4 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 2 Chlorophyllase Lipase_3 PF01764.25 EEQ37400.1 - 0.0052 16.6 0.0 0.0098 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.9 EEQ37400.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase DUF915 PF06028.11 EEQ37400.1 - 0.066 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Vps26 PF03643.15 EEQ37400.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 Abhydrolase_1 PF00561.20 EEQ37400.1 - 0.38 10.3 3.1 1.9 8.0 0.3 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.16 EEQ37401.1 - 1.1e-30 106.8 47.0 1.9e-25 89.6 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ37401.1 - 2.8e-19 69.3 17.8 6e-19 68.2 17.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter PLA2_B PF01735.18 EEQ37402.1 - 1.7e-199 663.3 3.8 2.2e-199 663.0 3.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EEQ37402.1 - 0.15 12.3 1.8 0.31 11.3 1.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain SNARE_assoc PF09335.11 EEQ37403.1 - 1.1e-18 67.9 3.3 1.1e-18 67.9 3.3 1.9 2 1 0 2 2 2 1 SNARE associated Golgi protein TctB PF07331.11 EEQ37403.1 - 0.0017 18.6 4.9 0.0017 18.6 4.9 2.2 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family YqhR PF11085.8 EEQ37403.1 - 0.26 11.2 4.6 1.1 9.2 1.9 2.4 2 0 0 2 2 2 0 Conserved membrane protein YqhR DUF2207 PF09972.9 EEQ37403.1 - 2.2 6.9 6.5 0.86 8.3 3.8 1.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) LIM PF00412.22 EEQ37404.1 - 3.5e-12 46.4 18.9 4.4e-09 36.4 6.3 2.4 2 0 0 2 2 2 2 LIM domain Paramyx_P_V_C PF03210.13 EEQ37404.1 - 0.094 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Ribosomal_L23eN PF03939.13 EEQ37405.1 - 3.2e-20 72.1 10.4 3.2e-20 72.1 10.4 1.8 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EEQ37405.1 - 1.1e-14 54.5 2.2 1.1e-14 54.5 2.2 2.3 2 1 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L6 PF00347.23 EEQ37405.1 - 0.0093 16.6 0.7 0.016 15.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L6 HPTransfase PF10090.9 EEQ37405.1 - 0.029 14.2 0.2 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Histidine phosphotransferase C-terminal domain Ribosomal_S11 PF00411.19 EEQ37406.1 - 0.067 13.6 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S11 Pkinase PF00069.25 EEQ37407.1 - 5.1e-57 193.2 0.0 7.3e-57 192.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37407.1 - 3.5e-28 98.6 0.0 4.9e-28 98.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ37407.1 - 0.0033 16.8 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ37407.1 - 0.0044 16.4 0.0 0.0061 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like UPF0220 PF05255.11 EEQ37408.1 - 1.5e-70 236.1 5.8 1.7e-70 235.9 5.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) ESSS PF10183.9 EEQ37408.1 - 0.097 12.9 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1689 PF07954.11 EEQ37408.1 - 0.14 12.5 1.0 1.6 9.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) WD40 PF00400.32 EEQ37409.1 - 3.1e-32 110.1 9.8 3.7e-05 24.4 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37409.1 - 8.6e-19 67.6 0.1 5.7e-05 23.3 0.1 4.9 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ37409.1 - 9e-09 35.5 0.5 0.031 14.2 0.2 3.7 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EEQ37409.1 - 2.5e-07 30.3 2.8 0.0022 17.4 0.0 3.2 2 2 1 3 3 3 3 WD40-like domain Nup160 PF11715.8 EEQ37409.1 - 3.4e-07 29.3 1.1 0.0097 14.6 0.1 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ37409.1 - 1e-06 28.0 0.1 0.75 8.7 0.0 4.4 3 2 0 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Utp8 PF10395.9 EEQ37409.1 - 8.7e-05 21.2 0.9 0.029 12.9 0.4 2.6 2 1 0 3 3 3 2 Utp8 family SGL PF08450.12 EEQ37409.1 - 0.00022 20.9 0.1 0.007 16.0 0.1 2.4 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region CPSF_A PF03178.15 EEQ37409.1 - 0.0019 17.5 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region PALB2_WD40 PF16756.5 EEQ37409.1 - 0.0048 15.9 0.8 0.13 11.1 0.0 3.1 1 1 2 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 EEQ37409.1 - 0.0057 15.0 0.1 0.015 13.6 0.1 1.7 2 0 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz Pkinase PF00069.25 EEQ37410.1 - 7.2e-68 228.8 0.0 1.3e-67 227.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37410.1 - 1.7e-46 158.6 0.0 2.9e-46 157.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ37410.1 - 3.8e-08 33.0 0.2 3.6e-07 29.8 0.0 2.4 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EEQ37410.1 - 6e-06 25.3 0.0 1.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EEQ37410.1 - 0.012 15.0 0.0 0.026 13.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CorA PF01544.18 EEQ37411.1 - 0.014 14.7 10.6 0.047 13.0 10.4 2.0 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Apocytochr_F_C PF01333.19 EEQ37411.1 - 0.1 12.6 0.7 0.25 11.4 0.7 1.6 1 0 0 1 1 1 0 Apocytochrome F, C-terminal RhoGAP PF00620.27 EEQ37412.1 - 5.9e-06 26.2 0.1 2.8e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 RhoGAP domain Luciferase_N PF05295.11 EEQ37412.1 - 0.052 13.6 0.3 2.4 8.2 0.0 3.3 2 1 1 3 3 3 0 Luciferase/LBP N-terminal domain PPR_2 PF13041.6 EEQ37413.1 - 0.0096 16.1 0.4 0.039 14.1 0.0 2.4 2 0 0 2 2 2 1 PPR repeat family IpaB_EvcA PF03278.13 EEQ37413.1 - 0.014 15.1 1.7 0.027 14.2 1.7 1.5 1 0 0 1 1 1 0 IpaB/EvcA family PPR_3 PF13812.6 EEQ37413.1 - 0.017 15.2 3.9 0.1 12.7 0.6 3.1 3 1 0 3 3 3 0 Pentatricopeptide repeat domain Endonuc-PvuII PF09225.10 EEQ37413.1 - 0.021 14.6 1.2 1.6 8.5 0.0 3.1 2 1 0 3 3 3 0 Restriction endonuclease PvuII PMC2NT PF08066.12 EEQ37413.1 - 0.11 13.2 0.3 12 6.7 0.1 3.2 3 0 0 3 3 3 0 PMC2NT (NUC016) domain eIF3_subunit PF08597.10 EEQ37414.1 - 2.3e-61 207.8 19.9 2.6e-61 207.6 19.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit TEX19 PF15553.6 EEQ37414.1 - 0.086 12.8 5.0 0.19 11.7 5.0 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 PBP1_TM PF14812.6 EEQ37414.1 - 4.1 7.9 12.0 0.91 9.9 0.4 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP-synt_E PF05680.12 EEQ37414.1 - 6.3 7.2 13.7 2.3 8.6 10.2 2.2 2 0 0 2 2 2 0 ATP synthase E chain SET PF00856.28 EEQ37415.1 - 2.1e-09 38.0 0.0 6.1e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 SET domain DUF2122 PF09895.9 EEQ37415.1 - 0.002 18.5 0.0 0.0047 17.3 0.0 1.6 1 0 0 1 1 1 1 RecB-family nuclease (DUF2122) Thioredoxin PF00085.20 EEQ37416.1 - 7.4e-33 112.6 0.1 8.2e-33 112.5 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EEQ37416.1 - 1.8e-08 34.8 0.2 1.5e-07 31.8 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EEQ37416.1 - 7.5e-07 29.4 0.1 7.5e-05 23.0 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EEQ37416.1 - 2.7e-05 24.0 0.0 3.1e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 EEQ37416.1 - 5.8e-05 23.2 0.1 0.00014 22.0 0.0 1.6 1 1 1 2 2 2 1 Glutaredoxin Redoxin PF08534.10 EEQ37416.1 - 8.4e-05 22.3 0.2 0.0053 16.5 0.0 2.1 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 EEQ37416.1 - 0.00017 21.0 0.1 0.0002 20.8 0.1 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 EEQ37416.1 - 0.00022 21.2 0.0 0.00034 20.6 0.0 1.2 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EEQ37416.1 - 0.00024 21.0 0.1 0.0004 20.3 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 EEQ37416.1 - 0.00042 20.1 0.0 0.00046 20.0 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 TraF PF13728.6 EEQ37416.1 - 0.0023 17.8 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EEQ37416.1 - 0.014 15.6 0.1 0.032 14.4 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.16 EEQ37416.1 - 0.014 14.3 0.0 0.015 14.2 0.0 1.0 1 0 0 1 1 1 0 Phosducin Thioredoxin_5 PF13743.6 EEQ37416.1 - 0.05 13.3 0.3 0.19 11.4 0.1 1.9 1 1 1 2 2 2 0 Thioredoxin Y_phosphatase PF00102.27 EEQ37417.1 - 2.1e-57 194.4 0.1 3.1e-57 193.8 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EEQ37417.1 - 3.6e-06 27.5 0.0 9.3e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 EEQ37417.1 - 0.0025 17.8 0.0 0.0072 16.3 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF1110 PF06533.12 EEQ37417.1 - 0.2 11.6 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1110) DUF4805 PF16063.5 EEQ37418.1 - 0.0067 15.8 1.1 0.014 14.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4805) ChlI PF13541.6 EEQ37419.1 - 0.1 12.5 0.5 18 5.2 0.0 2.3 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase TRAPP PF04051.16 EEQ37420.1 - 4.6e-44 149.7 0.0 6e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Acetyltransf_1 PF00583.25 EEQ37421.1 - 1e-13 51.5 0.0 1.4e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ37421.1 - 1.7e-07 31.2 0.1 2.3e-07 30.8 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ37421.1 - 1.1e-05 25.7 0.0 1.8e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ37421.1 - 2.7e-05 24.1 0.0 4.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EEQ37421.1 - 0.00063 19.8 0.2 0.0019 18.3 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EEQ37421.1 - 0.0033 18.1 0.0 0.0062 17.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EEQ37421.1 - 0.035 13.6 0.4 0.25 10.8 0.1 2.0 2 0 0 2 2 2 0 Putative acetyl-transferase KH_8 PF17903.1 EEQ37422.1 - 1.4e-05 25.1 0.0 3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EEQ37422.1 - 0.055 13.3 0.3 0.13 12.1 0.3 1.6 1 0 0 1 1 1 0 KH domain MDM31_MDM32 PF08118.11 EEQ37423.1 - 4.7e-99 332.5 3.5 1.2e-67 228.8 1.5 2.2 1 1 1 2 2 2 2 Yeast mitochondrial distribution and morphology (MDM) proteins G-patch_2 PF12656.7 EEQ37424.1 - 6.9e-18 64.5 0.0 1.8e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 G-patch domain TFIID-18kDa PF02269.16 EEQ37426.1 - 2.4e-34 117.2 0.1 1.8e-33 114.4 0.0 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 EEQ37426.1 - 0.17 12.0 1.1 0.35 11.0 0.3 2.0 2 1 0 2 2 2 0 hTAFII28-like protein conserved region Syntaxin-6_N PF09177.11 EEQ37427.1 - 1.2e-11 45.1 6.5 2.2e-11 44.2 1.1 2.7 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EEQ37427.1 - 5.1e-05 23.2 0.9 0.00013 21.9 0.9 1.7 1 0 0 1 1 1 1 SNARE domain DUF16 PF01519.16 EEQ37427.1 - 0.026 15.0 3.9 0.026 15.0 3.9 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF2420 PF10336.9 EEQ37427.1 - 0.036 14.1 0.7 0.036 14.1 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) CAMP_factor PF07373.11 EEQ37427.1 - 0.039 13.5 1.5 0.061 12.9 0.4 1.6 1 1 0 1 1 1 0 CAMP factor (Cfa) DUF1657 PF07870.11 EEQ37427.1 - 0.067 13.1 0.9 0.067 13.1 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) DUF1640 PF07798.11 EEQ37427.1 - 0.13 12.3 10.5 0.14 12.2 0.0 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1640) HSBP1 PF06825.12 EEQ37427.1 - 0.18 11.7 0.1 0.18 11.7 0.1 4.1 6 0 0 6 6 6 0 Heat shock factor binding protein 1 Sec20 PF03908.13 EEQ37427.1 - 0.48 10.4 3.5 0.47 10.4 0.1 2.5 2 2 0 2 2 2 0 Sec20 ACCA PF03255.14 EEQ37427.1 - 2.1 8.2 6.4 3.8 7.4 3.4 2.6 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit BST2 PF16716.5 EEQ37427.1 - 3 8.5 10.9 2.5 8.8 2.1 2.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 Dpy-30 PF05186.13 EEQ37428.1 - 1.2e-14 53.7 0.1 1.6e-14 53.3 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif Mito_carr PF00153.27 EEQ37429.1 - 1.2e-09 37.9 0.1 0.0039 17.1 0.0 3.5 3 1 0 3 3 3 2 Mitochondrial carrier protein Vps5 PF09325.10 EEQ37430.1 - 8.8e-11 41.8 9.2 8.8e-11 41.8 9.2 2.2 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EEQ37430.1 - 6.9e-05 22.8 0.1 6.9e-05 22.8 0.1 2.8 3 1 0 3 3 3 1 PX domain Sod_Fe_C PF02777.18 EEQ37431.1 - 5.3e-32 110.0 0.6 5.3e-32 110.0 0.6 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EEQ37431.1 - 1.3e-28 99.3 2.8 2.5e-28 98.4 2.8 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 EEQ37431.1 - 0.017 15.2 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif Snf7 PF03357.21 EEQ37432.1 - 5.1e-11 42.5 15.5 6.9e-11 42.1 15.5 1.3 1 0 0 1 1 1 1 Snf7 FKBP_C PF00254.28 EEQ37432.1 - 0.089 13.1 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase GrpE PF01025.19 EEQ37432.1 - 0.57 9.8 9.0 0.15 11.7 5.1 1.8 1 1 1 2 2 2 0 GrpE DUF3886 PF13025.6 EEQ37432.1 - 3.3 8.0 11.3 0.16 12.2 4.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3886) TPR_1 PF00515.28 EEQ37433.1 - 0.00015 21.4 0.9 5.1 7.1 0.2 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ37433.1 - 0.031 14.4 5.0 7.9 6.9 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat Cid2 PF09774.9 EEQ37434.1 - 4.2e-34 118.3 8.5 2e-33 116.1 8.5 1.8 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Pkinase PF00069.25 EEQ37435.1 - 3.6e-65 220.0 0.1 5.7e-65 219.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37435.1 - 2.2e-30 105.8 0.1 1.3e-28 100.1 0.1 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ37435.1 - 2.8e-08 33.4 0.0 4.4e-07 29.5 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEQ37435.1 - 2.3e-05 23.5 0.1 2.3e-05 23.5 0.1 2.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EEQ37435.1 - 0.0014 18.0 0.0 0.0038 16.6 0.0 1.6 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M3 PF01432.20 EEQ37436.1 - 1.9e-110 370.2 0.9 2.6e-110 369.8 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EEQ37436.1 - 0.038 13.6 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like tRNA-synt_2b PF00587.25 EEQ37437.1 - 5.6e-25 88.3 0.0 1.3e-24 87.1 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EEQ37437.1 - 8.6e-11 42.0 7.7 1.3e-10 41.4 7.7 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF241 PF03087.14 EEQ37437.1 - 0.0096 15.8 3.5 0.016 15.0 3.3 1.4 1 1 0 1 1 1 1 Arabidopsis protein of unknown function DUF4349 PF14257.6 EEQ37437.1 - 0.014 14.9 1.0 0.024 14.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) FemAB PF02388.16 EEQ37437.1 - 0.077 11.9 6.4 0.14 11.0 1.7 2.2 1 1 1 2 2 2 0 FemAB family DUF1664 PF07889.12 EEQ37437.1 - 0.22 11.6 1.5 0.43 10.6 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 EEQ37437.1 - 1.1 9.7 7.1 7.1 7.1 3.1 2.4 1 1 1 2 2 2 0 Snapin/Pallidin MitMem_reg PF13012.6 EEQ37438.1 - 0.015 15.7 1.9 0.015 15.7 1.9 3.0 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function MutS_III PF05192.18 EEQ37438.1 - 0.04 14.2 22.2 2.1 8.5 22.2 2.4 1 1 0 1 1 1 0 MutS domain III Vac_Fusion PF02346.16 EEQ37438.1 - 0.048 13.3 0.2 0.048 13.3 0.2 4.7 3 1 2 5 5 5 0 Chordopoxvirus multifunctional envelope protein A27 F-box-like_2 PF13013.6 EEQ37438.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain Baculo_PEP_C PF04513.12 EEQ37438.1 - 0.42 10.7 27.2 1.2 9.2 8.8 3.3 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus IFT57 PF10498.9 EEQ37438.1 - 1.3 7.9 30.8 0.21 10.6 5.9 3.1 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 GAS PF13851.6 EEQ37438.1 - 1.5 8.1 32.7 0.52 9.6 15.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 EEQ37438.1 - 3.8 7.8 19.9 3 8.2 1.8 4.4 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF3810 PF12725.7 EEQ37438.1 - 4.1 6.6 13.8 0.064 12.6 3.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3810) DUF2203 PF09969.9 EEQ37438.1 - 7.8 7.2 15.8 3.6 8.3 0.4 3.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Lgl_C PF08596.10 EEQ37439.1 - 2.5e-108 362.3 0.0 1.1e-107 360.2 0.0 1.9 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EEQ37439.1 - 1.2e-09 38.4 0.1 0.14 12.5 0.0 6.4 4 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ37439.1 - 0.00011 22.9 0.9 6.3 7.8 0.0 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat WD40_like PF17005.5 EEQ37439.1 - 0.017 14.5 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain IKKbetaNEMObind PF12179.8 EEQ37439.1 - 0.083 12.9 0.2 0.19 11.8 0.2 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain DPM2 PF07297.12 EEQ37440.1 - 3e-18 65.9 1.8 4e-18 65.5 1.8 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EEQ37440.1 - 0.004 17.1 1.2 0.0063 16.4 1.2 1.4 1 1 0 1 1 1 1 PIG-P DUF4083 PF13314.6 EEQ37440.1 - 0.0096 15.9 0.1 0.0096 15.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4083) Adap_comp_sub PF00928.21 EEQ37441.1 - 1.4e-46 159.1 0.7 1.6e-36 126.1 0.0 2.2 2 0 0 2 2 2 2 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEQ37441.1 - 0.00017 21.5 0.4 0.00029 20.8 0.4 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Cu-oxidase_2 PF07731.14 EEQ37443.1 - 9.8e-46 154.9 6.2 5.5e-41 139.5 0.5 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EEQ37443.1 - 1.9e-43 147.3 3.3 8.9e-40 135.4 0.3 3.6 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EEQ37443.1 - 1e-34 119.9 7.0 5.5e-30 104.6 2.1 3.6 3 0 0 3 3 3 3 Multicopper oxidase Abhydrolase_1 PF00561.20 EEQ37444.1 - 1.3e-16 61.0 0.0 1.9e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ37444.1 - 1.4e-12 48.7 0.0 2.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ37444.1 - 3.9e-09 36.1 0.0 8.2e-09 35.1 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EEQ37444.1 - 0.00017 21.5 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase ThiF PF00899.21 EEQ37445.1 - 9.9e-63 211.7 0.0 1.4e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EEQ37445.1 - 5.9e-23 80.8 0.0 1e-22 80.1 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EEQ37445.1 - 0.00072 19.6 0.2 0.0018 18.3 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Prolamin_like PF05617.11 EEQ37445.1 - 0.012 15.8 0.2 0.03 14.5 0.2 1.7 1 0 0 1 1 1 0 Prolamin-like PglD_N PF17836.1 EEQ37445.1 - 0.04 14.6 0.0 0.15 12.7 0.0 2.0 2 0 0 2 2 2 0 PglD N-terminal domain Ecm33 PF12454.8 EEQ37445.1 - 0.067 13.3 1.0 0.13 12.4 1.0 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TrkA_N PF02254.18 EEQ37445.1 - 0.11 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 EEQ37445.1 - 0.12 12.8 0.0 0.34 11.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Rho_N PF07498.12 EEQ37445.1 - 0.19 11.7 0.0 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain Rad52_Rad22 PF04098.15 EEQ37446.1 - 6.9e-58 194.9 0.0 9.9e-58 194.4 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein LSM PF01423.22 EEQ37447.1 - 3.1e-15 55.6 0.1 3.6e-15 55.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.14 EEQ37447.1 - 0.01 15.7 0.2 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 PhnA domain Hfq PF17209.3 EEQ37447.1 - 0.014 15.1 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Hfq protein DUF908 PF06012.12 EEQ37448.1 - 4e-71 240.3 1.6 3.9e-70 237.1 0.1 3.0 2 1 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 EEQ37448.1 - 3.7e-53 180.8 0.0 3.7e-53 180.8 0.0 3.6 4 1 0 4 4 4 1 Domain of Unknown Function (DUF913) UBM PF14377.6 EEQ37448.1 - 2.2e-17 61.8 7.8 2.1e-09 36.5 0.4 2.7 2 0 0 2 2 2 2 Ubiquitin binding region DUF3987 PF13148.6 EEQ37448.1 - 8.2 5.3 7.4 39 3.1 8.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) HECT PF00632.25 EEQ37449.1 - 1.3e-96 323.7 0.0 2.2e-96 323.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DegQ PF08181.11 EEQ37449.1 - 0.078 13.1 0.3 0.25 11.4 0.3 1.9 1 0 0 1 1 1 0 DegQ (SacQ) family 4HBT_2 PF13279.6 EEQ37450.1 - 1.9e-11 44.5 0.0 3.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily ELO PF01151.18 EEQ37452.1 - 7.2e-49 166.6 21.8 8.3e-49 166.4 21.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CNH PF00780.22 EEQ37453.1 - 1.8e-73 247.5 0.0 3e-73 246.8 0.0 1.4 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EEQ37453.1 - 1.6e-39 136.0 0.6 1.6e-39 136.0 0.6 2.0 2 0 0 2 2 2 1 RhoGEF domain PH_5 PF15405.6 EEQ37453.1 - 4.8e-24 85.0 0.9 1e-23 83.9 0.9 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain DEP PF00610.21 EEQ37453.1 - 1.1e-12 47.8 0.0 2.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ribonuc_2-5A PF06479.12 EEQ37453.1 - 0.0057 16.8 0.2 0.35 11.1 0.6 2.5 2 0 0 2 2 2 1 Ribonuclease 2-5A ChitinaseA_N PF08329.10 EEQ37453.1 - 0.095 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Tom22 PF04281.13 EEQ37454.1 - 0.018 14.8 0.1 0.033 14.0 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 P21-Arc PF04062.14 EEQ37456.1 - 1e-74 250.4 0.0 1.1e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ICMT PF04140.14 EEQ37457.1 - 8e-21 74.3 0.3 8e-21 74.3 0.3 1.9 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EEQ37457.1 - 2.6e-14 53.5 1.1 2.6e-14 53.5 1.1 2.1 2 1 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EEQ37457.1 - 0.0003 19.7 0.8 0.00048 19.0 0.8 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EEQ37457.1 - 0.0005 19.7 0.4 0.00065 19.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 EEQ37457.1 - 0.0031 17.1 7.0 0.026 14.0 7.0 2.1 1 1 0 1 1 1 1 NnrU protein PrgI PF12666.7 EEQ37457.1 - 2.8 8.7 6.9 1.8 9.3 0.1 2.7 2 1 0 3 3 3 0 PrgI family protein PhoR PF11808.8 EEQ37457.1 - 4.9 7.6 10.5 4 7.9 1.9 2.5 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR ICMT PF04140.14 EEQ37458.1 - 1.6e-23 82.9 0.2 3.5e-23 81.8 0.2 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EEQ37458.1 - 8.7e-14 51.8 3.5 1.9e-13 50.7 3.5 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 EEQ37458.1 - 1.2e-07 31.5 0.8 1.6e-07 31.1 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) UPF0242 PF06785.11 EEQ37458.1 - 0.057 13.5 0.1 0.089 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Steroid_dh PF02544.16 EEQ37458.1 - 0.15 12.1 9.7 0.11 12.5 7.3 1.8 1 1 1 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase PsbL PF02419.17 EEQ37458.1 - 0.29 11.2 1.6 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 PsbL protein FA_desaturase PF00487.24 EEQ37459.1 - 1.4e-24 87.3 20.3 2e-24 86.8 20.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EEQ37459.1 - 0.00078 19.6 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TMEM213 PF15192.6 EEQ37459.1 - 1.5 8.9 3.9 0.42 10.6 0.4 1.8 2 0 0 2 2 2 0 TMEM213 family Mito_carr PF00153.27 EEQ37460.1 - 4e-28 97.2 6.1 1.8e-13 50.2 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein TPT PF03151.16 EEQ37461.1 - 3.3e-41 141.5 16.8 8.2e-41 140.2 16.8 1.6 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EEQ37461.1 - 0.29 11.3 34.3 3.4 7.8 14.6 3.2 2 2 0 2 2 2 0 EamA-like transporter family DUF983 PF06170.12 EEQ37461.1 - 0.9 10.0 5.3 0.28 11.6 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Na_H_Exchanger PF00999.21 EEQ37462.1 - 3.9e-70 236.6 39.3 4.9e-70 236.2 39.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Ndc1_Nup PF09531.10 EEQ37463.1 - 9.4e-56 189.7 2.5 1.2e-55 189.4 2.5 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ndc1_Nup PF09531.10 EEQ37464.1 - 7.7e-39 133.9 21.8 9.8e-39 133.5 21.8 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup ERCC4 PF02732.15 EEQ37466.1 - 3.1e-06 27.5 0.0 5.8e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain DUF2400 PF09674.10 EEQ37466.1 - 0.0099 15.9 0.5 0.014 15.4 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2400) ERCC4 PF02732.15 EEQ37467.1 - 2.2e-11 44.2 0.2 3.7e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 EEQ37468.1 - 0.0096 16.3 0.0 0.015 15.7 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_3 PF12836.7 EEQ37468.1 - 0.04 14.2 0.1 0.054 13.8 0.1 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif PRP3 PF08572.10 EEQ37469.1 - 6.8e-63 212.4 15.0 1.3e-62 211.4 15.0 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EEQ37469.1 - 2.5e-37 128.2 2.4 2.5e-37 128.2 2.4 3.0 2 2 0 2 2 2 1 Protein of unknown function (DUF1115) DUF4090 PF13319.6 EEQ37469.1 - 0.072 13.3 2.1 0.28 11.4 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4090) Ribonuc_red_lgC PF02867.15 EEQ37470.1 - 5.6e-189 629.0 0.0 7.1e-189 628.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EEQ37470.1 - 1.4e-23 82.7 0.0 4.3e-23 81.1 0.0 1.9 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EEQ37470.1 - 1.8e-17 63.7 0.0 5e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain Ocular_alb PF02101.15 EEQ37470.1 - 0.065 12.1 0.2 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 Ocular albinism type 1 protein OPT PF03169.15 EEQ37471.1 - 3e-187 624.0 51.1 3.5e-187 623.8 51.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF543 PF04418.12 EEQ37471.1 - 0.029 14.4 1.8 2.7 8.0 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) YlaC PF10777.9 EEQ37471.1 - 0.12 12.2 0.2 0.43 10.4 0.2 2.0 1 0 0 1 1 1 0 Inner membrane protein YlaC CcmD PF04995.14 EEQ37471.1 - 2.7 8.2 0.0 2.7 8.2 0.0 3.3 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) LCCL PF03815.19 EEQ37472.1 - 1.9e-07 31.1 0.2 3.6e-07 30.2 0.2 1.3 1 0 0 1 1 1 1 LCCL domain Coatomer_E PF04733.14 EEQ37473.1 - 3.4e-12 46.4 1.6 1.1e-09 38.1 0.4 2.3 2 1 0 2 2 2 2 Coatomer epsilon subunit TPR_19 PF14559.6 EEQ37473.1 - 0.00013 22.4 1.2 0.024 15.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ37473.1 - 0.013 16.1 0.0 9.1 7.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Septin PF00735.18 EEQ37474.1 - 2.1e-77 260.1 1.4 2.1e-77 260.1 1.4 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EEQ37474.1 - 4.4e-10 39.7 0.2 2.8e-09 37.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EEQ37474.1 - 0.00027 20.4 0.4 0.00056 19.3 0.0 1.8 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EEQ37474.1 - 0.00037 20.4 4.4 0.00051 20.0 0.2 2.6 3 0 0 3 3 3 1 RsgA GTPase FeoB_N PF02421.18 EEQ37474.1 - 0.00049 19.7 0.1 0.0047 16.5 0.1 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EEQ37474.1 - 0.00081 19.0 0.7 0.021 14.4 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EEQ37474.1 - 0.00094 19.7 0.1 0.0031 18.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Roc PF08477.13 EEQ37474.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EEQ37474.1 - 0.011 15.5 0.2 0.025 14.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.13 EEQ37474.1 - 0.016 14.3 0.3 0.036 13.1 0.3 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 EEQ37474.1 - 0.025 14.6 0.6 0.025 14.6 0.6 2.5 2 2 0 2 2 2 0 Dynamin family Ras PF00071.22 EEQ37474.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Ras family AAA_22 PF13401.6 EEQ37474.1 - 0.11 12.8 0.0 0.31 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain KRE9 PF05390.11 EEQ37475.1 - 1.3e-34 118.9 14.9 2.6e-34 118.0 14.9 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 EEQ37475.1 - 4.6e-20 72.2 5.2 3.5e-19 69.4 1.1 2.4 2 0 0 2 2 2 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mgm101p PF06420.12 EEQ37476.1 - 4.7e-86 286.6 0.1 7.2e-86 286.0 0.0 1.3 2 0 0 2 2 2 1 Mitochondrial genome maintenance MGM101 Tim17 PF02466.19 EEQ37477.1 - 0.027 14.8 0.5 0.04 14.3 0.5 1.3 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family MAS20 PF02064.15 EEQ37478.1 - 5.6e-42 142.9 1.2 7.2e-42 142.5 1.2 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor Homoserine_dh PF00742.19 EEQ37480.1 - 1.4e-50 171.6 0.0 1.9e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EEQ37480.1 - 7.6e-19 68.5 0.0 1.4e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EEQ37480.1 - 3.5e-05 24.2 0.0 0.0001 22.7 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RNA_pol_L_2 PF13656.6 EEQ37480.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain IML1 PF12257.8 EEQ37481.1 - 7.2e-99 330.5 0.0 1.1e-98 329.9 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EEQ37481.1 - 9.4e-27 92.9 0.1 2.1e-26 91.8 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peroxin-22 PF12827.7 EEQ37482.1 - 2.7e-30 104.6 0.6 3.5e-30 104.2 0.6 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family SWM_repeat PF13753.6 EEQ37482.1 - 0.023 14.8 0.3 0.046 13.9 0.2 1.6 1 1 0 1 1 1 0 Putative flagellar system-associated repeat ArlS_N PF18719.1 EEQ37482.1 - 0.13 12.5 1.7 1.7 8.9 1.5 2.2 2 0 0 2 2 2 0 ArlS sensor domain RasGEF PF00617.19 EEQ37483.1 - 6.2e-47 160.1 2.3 2e-46 158.4 1.0 2.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EEQ37483.1 - 1.1e-13 51.3 7.2 1.4e-13 51.0 4.2 2.8 2 0 0 2 2 2 1 RasGEF N-terminal motif Forkhead PF00250.18 EEQ37484.1 - 1.7e-17 63.4 0.1 4e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EEQ37484.1 - 2.2e-09 37.5 0.2 4.6e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 FHA domain CCDC23 PF15674.5 EEQ37484.1 - 1.1 9.3 5.1 0.94 9.5 2.1 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 23 Proteasome PF00227.26 EEQ37485.1 - 3e-47 160.6 0.1 3.6e-47 160.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L5 PF00281.19 EEQ37486.1 - 5.6e-21 74.6 0.0 1.4e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 EEQ37486.1 - 1.4e-20 73.3 0.0 2.1e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus HTH_ABP1_N PF18107.1 EEQ37486.1 - 0.0028 17.3 0.3 0.0061 16.2 0.3 1.5 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain PHF5 PF03660.14 EEQ37487.1 - 5e-46 155.2 12.5 5.9e-46 155.0 12.5 1.0 1 0 0 1 1 1 1 PHF5-like protein zinc-ribbons_6 PF07191.12 EEQ37487.1 - 0.0098 15.9 7.3 0.0098 15.9 7.3 2.1 1 1 1 2 2 2 1 zinc-ribbons COPI_C PF06957.11 EEQ37487.1 - 0.19 10.4 2.3 0.26 10.0 2.3 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus zf-RING_2 PF13639.6 EEQ37487.1 - 6.2 7.2 19.7 0.16 12.4 5.5 2.8 2 1 1 3 3 3 0 Ring finger domain Prok-RING_4 PF14447.6 EEQ37487.1 - 8.8 6.3 18.5 6.7 6.7 0.2 3.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EEQ37488.1 - 6.4e-14 52.0 23.2 2.5e-10 40.5 9.0 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ37488.1 - 3.5e-08 33.2 6.9 3.5e-08 33.2 6.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ37488.1 - 1.4e-07 31.1 11.8 2.7e-07 30.2 2.0 2.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EEQ37488.1 - 4.3e-07 29.8 15.4 3.4e-06 27.0 4.2 3.0 2 2 0 2 2 2 2 RING-type zinc-finger PHD PF00628.29 EEQ37488.1 - 5.1e-06 26.3 11.6 5.1e-06 26.3 11.6 3.1 2 1 1 3 3 3 1 PHD-finger zf-C3HC4 PF00097.25 EEQ37488.1 - 1.4e-05 24.9 7.6 1.4e-05 24.9 7.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ37488.1 - 2.7e-05 24.4 23.9 0.00021 21.5 10.0 2.6 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EEQ37488.1 - 0.00013 21.8 6.0 0.00013 21.8 6.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ37488.1 - 0.00036 20.4 23.5 0.00062 19.7 6.4 2.5 2 0 0 2 2 2 2 zinc-RING finger domain PHD_2 PF13831.6 EEQ37488.1 - 0.00036 20.0 2.8 0.0011 18.5 2.8 1.9 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 EEQ37488.1 - 0.0061 16.2 7.3 0.0061 16.2 7.3 2.6 2 1 0 2 2 2 1 PHD/FYVE-zinc-finger like domain PHD_3 PF13922.6 EEQ37488.1 - 0.0063 16.9 0.4 0.018 15.4 0.4 1.8 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx FXR_C1 PF16096.5 EEQ37488.1 - 0.028 14.6 0.9 0.065 13.4 0.9 1.6 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF2318 PF10080.9 EEQ37488.1 - 0.084 13.0 5.0 0.21 11.7 5.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-RING_9 PF13901.6 EEQ37488.1 - 0.26 11.2 21.7 0.22 11.5 8.3 2.3 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Prok-RING_4 PF14447.6 EEQ37488.1 - 6.8 6.6 27.1 1.6 8.7 11.5 3.4 2 2 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EEQ37488.1 - 8.6 6.6 20.4 2.4 8.3 6.6 2.7 2 1 0 2 2 2 0 RING-variant domain Cofilin_ADF PF00241.20 EEQ37489.1 - 2.1e-26 92.1 0.0 3.3e-12 46.3 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein STD1 PF17235.2 EEQ37490.1 - 8.9e-36 123.5 1.1 1.7e-35 122.5 1.1 1.4 1 0 0 1 1 1 1 STD1/MTH1 ACPS PF01648.20 EEQ37490.1 - 0.11 12.6 0.1 0.33 11.1 0.1 1.8 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily DUF498 PF04430.14 EEQ37491.1 - 2.2e-16 59.9 0.0 2.4e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Pil1 PF13805.6 EEQ37493.1 - 1.9e-126 421.0 0.6 2.5e-126 420.6 0.6 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.11 EEQ37493.1 - 0.028 13.9 1.7 0.048 13.1 1.7 1.3 1 0 0 1 1 1 0 FAM92 protein DUF2385 PF09539.10 EEQ37493.1 - 0.097 13.2 0.1 2.5 8.7 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) Mpv17_PMP22 PF04117.12 EEQ37494.1 - 6.7e-20 71.1 6.8 6.7e-20 71.1 6.8 1.9 1 1 1 2 2 2 1 Mpv17 / PMP22 family B56 PF01603.20 EEQ37495.1 - 3.8e-173 576.2 11.8 1.3e-162 541.5 8.4 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EEQ37495.1 - 0.22 11.4 4.2 1.3 8.9 0.5 2.6 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Ndc1_Nup PF09531.10 EEQ37495.1 - 2.3 6.8 9.3 3.2 6.3 9.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 EEQ37495.1 - 2.6 6.8 15.3 3.8 6.2 15.3 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4614 PF15391.6 EEQ37495.1 - 3.3 7.7 18.0 7.1 6.6 18.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) IMPDH PF00478.25 EEQ37496.1 - 6.9e-136 452.8 0.8 8e-136 452.6 0.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EEQ37496.1 - 3.5e-14 53.0 0.1 3.3e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EEQ37496.1 - 2.5e-08 33.4 2.6 3.1e-07 29.7 3.6 2.2 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EEQ37496.1 - 4.2e-08 33.0 1.3 1.5e-05 24.6 0.7 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EEQ37496.1 - 0.00015 21.3 0.5 0.00073 19.1 0.5 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EEQ37496.1 - 0.00048 19.5 1.1 0.0024 17.2 0.4 2.0 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG NanE PF04131.14 EEQ37496.1 - 0.0036 16.5 0.1 0.0075 15.5 0.1 1.5 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase Aldolase PF01081.19 EEQ37496.1 - 0.0045 16.4 0.0 0.012 15.0 0.0 1.7 1 0 0 1 1 1 1 KDPG and KHG aldolase YpsA PF06908.11 EEQ37496.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family IMPDH PF00478.25 EEQ37497.1 - 1.6e-32 112.9 0.0 1.9e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TraQ PF09679.10 EEQ37497.1 - 0.082 12.8 0.3 3.6 7.6 0.0 2.2 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin chaperone (TraQ) CH PF00307.31 EEQ37498.1 - 1.3e-12 47.8 0.0 1.8e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Ribosomal_L28e PF01778.17 EEQ37499.1 - 1.3e-38 132.3 0.6 1.3e-38 132.3 0.6 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EEQ37499.1 - 1.8e-30 105.5 11.3 1.8e-30 105.5 11.3 2.6 2 1 1 3 3 3 1 Mak16 protein C-terminal region Ribosomal_L24e PF01246.20 EEQ37499.1 - 0.00016 21.8 0.2 0.00044 20.4 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e BUD22 PF09073.10 EEQ37499.1 - 0.0011 18.4 16.9 0.0015 18.0 16.9 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EEQ37499.1 - 0.079 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain KilA-N PF04383.13 EEQ37500.1 - 6.1e-05 22.8 0.0 0.014 15.2 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain Aa_trans PF01490.18 EEQ37501.1 - 1.8e-48 165.3 28.8 2e-48 165.1 28.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RRM_1 PF00076.22 EEQ37502.1 - 1.2e-12 47.4 2.4 0.0033 17.2 0.1 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.9 EEQ37502.1 - 2.5e-05 23.9 2.2 2.5e-05 23.9 2.2 3.1 2 0 0 2 2 2 1 Putative RRM domain Ras PF00071.22 EEQ37503.1 - 6.7e-49 165.6 0.0 8.2e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ37503.1 - 2.5e-29 101.9 0.0 6e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ37503.1 - 1.5e-10 40.8 0.0 2.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EEQ37503.1 - 0.00062 19.8 0.0 0.0014 18.7 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EEQ37503.1 - 0.00075 19.9 0.0 0.0041 17.5 0.0 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.12 EEQ37503.1 - 0.0013 18.1 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 EEQ37503.1 - 0.023 14.2 0.1 0.041 13.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 EEQ37503.1 - 0.028 13.6 1.2 1.5 7.9 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit RsgA_GTPase PF03193.16 EEQ37503.1 - 0.031 14.2 0.1 6.4 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EEQ37503.1 - 0.037 13.5 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EEQ37503.1 - 0.046 13.4 0.1 0.079 12.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ37503.1 - 0.094 12.7 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EEQ37503.1 - 0.099 12.8 0.2 0.22 11.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.18 EEQ37503.1 - 0.13 11.5 0.1 0.25 10.6 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 EEQ37503.1 - 0.14 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.10 EEQ37503.1 - 0.16 11.4 0.0 0.25 10.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATPase PF06745.13 EEQ37503.1 - 0.17 11.2 0.2 0.25 10.6 0.2 1.2 1 0 0 1 1 1 0 KaiC zf-U1 PF06220.12 EEQ37504.1 - 4.8e-17 61.4 10.2 1.1e-16 60.3 10.2 1.7 1 0 0 1 1 1 1 U1 zinc finger ADIP PF11559.8 EEQ37505.1 - 4.1e-29 101.6 16.2 4.1e-29 101.6 16.2 2.5 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding Troponin PF00992.20 EEQ37505.1 - 0.04 14.2 17.3 0.039 14.3 7.8 2.8 2 1 1 3 3 3 0 Troponin Methyltransf_16 PF10294.9 EEQ37505.1 - 0.079 12.7 2.6 0.28 10.9 2.1 2.2 1 1 1 2 2 2 0 Lysine methyltransferase CDC4_D PF16856.5 EEQ37505.1 - 0.11 12.4 4.9 3.5 7.6 1.5 3.3 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain TRAF_BIRC3_bd PF16673.5 EEQ37505.1 - 0.13 12.0 2.2 0.43 10.4 2.2 1.9 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain ABC_tran_CTD PF16326.5 EEQ37505.1 - 0.44 10.8 17.7 0.17 12.2 5.4 4.5 3 1 2 5 5 5 0 ABC transporter C-terminal domain Imm51 PF15595.6 EEQ37505.1 - 0.54 10.2 6.0 8.2 6.4 0.1 3.7 4 0 0 4 4 4 0 Immunity protein 51 Golgin_A5 PF09787.9 EEQ37505.1 - 0.82 9.1 22.2 0.25 10.8 11.4 2.7 3 0 0 3 3 3 0 Golgin subfamily A member 5 Borrelia_orfD PF02999.14 EEQ37505.1 - 0.86 10.0 6.8 0.61 10.4 1.5 3.0 2 1 0 2 2 2 0 Borrelia orf-D family DUF4407 PF14362.6 EEQ37505.1 - 0.94 8.8 16.2 0.066 12.6 8.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1848 PF08902.11 EEQ37505.1 - 1.3 8.6 8.4 0.8 9.4 5.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1848) Bacillus_HBL PF05791.11 EEQ37505.1 - 2.9 7.7 27.0 1.5 8.6 7.7 3.8 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) Tup_N PF08581.10 EEQ37505.1 - 4 7.8 25.0 5.2 7.4 1.3 3.9 3 1 0 4 4 4 0 Tup N-terminal DUF1664 PF07889.12 EEQ37505.1 - 5.5 7.0 13.8 1 9.4 4.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EEQ37505.1 - 9.6 6.3 30.6 0.12 12.3 2.4 4.6 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding RF-1 PF00472.20 EEQ37506.1 - 3.8e-24 84.9 6.2 6.3e-24 84.1 6.2 1.3 1 0 0 1 1 1 1 RF-1 domain FAM176 PF14851.6 EEQ37506.1 - 0.38 10.4 4.2 0.5 10.0 4.2 1.2 1 0 0 1 1 1 0 FAM176 family MCM PF00493.23 EEQ37507.1 - 4.8e-104 346.3 0.2 8.7e-104 345.5 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EEQ37507.1 - 3.3e-38 130.4 0.7 6.2e-38 129.5 0.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ37507.1 - 1.5e-28 99.0 1.3 4.8e-28 97.4 1.3 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ37507.1 - 1.9e-15 57.4 0.4 5.1e-15 55.9 0.4 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ37507.1 - 3.2e-06 26.7 0.0 0.00064 19.2 0.0 2.4 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ37507.1 - 1.1e-05 25.4 0.0 3.5e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEQ37507.1 - 0.00018 21.4 0.2 0.00098 19.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ37507.1 - 0.028 14.1 0.0 0.85 9.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Prefoldin PF02996.17 EEQ37508.1 - 3.6e-28 97.9 5.0 4.3e-28 97.6 5.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EEQ37508.1 - 0.0044 16.9 0.2 0.0044 16.9 0.2 2.3 1 1 0 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.11 EEQ37508.1 - 0.35 11.4 4.3 1.1 9.8 4.2 2.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4385 PF14328.6 EEQ37509.1 - 0.051 13.6 0.1 0.081 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4385) EPV_E5 PF08135.11 EEQ37509.1 - 0.25 11.7 5.5 0.97 9.8 1.9 2.6 2 0 0 2 2 2 0 Major transforming protein E5 family Pescadillo_N PF06732.11 EEQ37510.1 - 1e-120 402.4 1.2 1.7e-120 401.7 1.2 1.2 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT_2 PF16589.5 EEQ37510.1 - 1.6e-08 34.8 0.0 3.4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EEQ37510.1 - 0.065 13.5 0.0 0.25 11.7 0.0 2.0 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Acyltransferase PF01553.21 EEQ37513.1 - 5e-11 42.4 0.0 2.2e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase Phage_tail_APC PF16778.5 EEQ37513.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Phage tail assembly chaperone protein Mac PF12464.8 EEQ37513.1 - 0.12 12.6 0.7 1.2 9.4 0.2 2.3 2 0 0 2 2 2 0 Maltose acetyltransferase PPR PF01535.20 EEQ37514.1 - 0.0058 16.8 0.4 12 6.4 0.0 4.6 5 0 0 5 5 5 1 PPR repeat PPR_2 PF13041.6 EEQ37514.1 - 0.007 16.5 0.1 49 4.2 0.0 4.7 4 1 0 4 4 4 2 PPR repeat family Kinesin PF00225.23 EEQ37515.1 - 3.4e-100 335.2 5.2 3.4e-100 335.2 5.2 2.8 2 1 2 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ37515.1 - 1.1e-50 171.5 0.1 1.1e-50 171.5 0.1 2.4 3 0 0 3 3 3 1 Microtubule binding TPR_MLP1_2 PF07926.12 EEQ37515.1 - 0.00042 20.4 4.5 0.00042 20.4 4.5 4.6 1 1 2 3 3 2 1 TPR/MLP1/MLP2-like protein ATG16 PF08614.11 EEQ37515.1 - 0.039 14.2 36.9 7.2 6.8 24.7 3.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 EEQ37515.1 - 0.38 9.6 40.0 0.011 14.6 16.8 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein HMMR_N PF15905.5 EEQ37515.1 - 0.44 10.0 43.2 0.99 8.8 11.1 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF812 PF05667.11 EEQ37515.1 - 0.87 8.4 39.3 0.012 14.6 24.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF812) TFA2_Winged_2 PF18121.1 EEQ37515.1 - 1.2 8.8 4.2 11 5.9 0.0 3.8 4 0 0 4 4 4 0 TFA2 Winged helix domain 2 Atg14 PF10186.9 EEQ37515.1 - 3.1 6.8 35.2 1.6 7.8 16.4 2.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fez1 PF06818.15 EEQ37515.1 - 3.4 8.1 40.2 2.4 8.6 6.0 4.1 2 1 1 3 3 3 0 Fez1 GAS PF13851.6 EEQ37515.1 - 5.2 6.4 47.7 0.016 14.5 6.1 3.3 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding Proteasom_Rpn13 PF04683.13 EEQ37517.1 - 0.1 13.1 0.0 0.4 11.3 0.0 2.0 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor SH3_1 PF00018.28 EEQ37518.1 - 9.5e-10 37.9 1.0 1.4e-09 37.4 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEQ37518.1 - 5.5e-09 35.7 1.4 7.2e-09 35.4 0.4 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EEQ37518.1 - 0.00013 21.6 0.0 0.00021 20.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4122 PF13498.6 EEQ37518.1 - 0.12 12.1 0.5 0.18 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) RWD PF05773.22 EEQ37519.1 - 3e-24 85.5 2.8 3e-24 85.5 2.8 1.6 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 EEQ37519.1 - 3.3e-07 30.7 7.8 3.3e-07 30.7 7.8 2.8 2 1 1 3 3 3 1 DRG Family Regulatory Proteins, Tma46 E2_bind PF08825.10 EEQ37519.1 - 0.032 14.4 0.7 0.075 13.2 0.7 1.6 1 0 0 1 1 1 0 E2 binding domain MSC PF09402.10 EEQ37520.1 - 1.3e-96 324.0 0.3 2.6e-96 323.0 0.3 1.5 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain EGF_MSP1_1 PF12946.7 EEQ37520.1 - 0.41 10.7 2.3 1 9.5 2.3 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 Zn_clus PF00172.18 EEQ37522.1 - 4.3e-09 36.4 10.3 7.5e-09 35.6 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EEQ37523.1 - 9.6e-45 149.7 9.5 7.3e-05 23.5 0.1 11.4 11 0 0 11 11 11 8 WD domain, G-beta repeat Utp13 PF08625.11 EEQ37523.1 - 1.2e-40 138.6 1.9 2.4e-40 137.7 1.9 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EEQ37523.1 - 2.8e-19 69.2 1.7 8.6e-06 26.0 0.0 7.3 4 4 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ37523.1 - 2.7e-05 23.0 12.6 0.23 10.1 0.0 5.9 4 2 0 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EEQ37523.1 - 0.00024 21.0 0.3 9.8 6.0 0.0 4.4 3 2 2 5 5 5 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.9 EEQ37523.1 - 0.00035 20.4 0.7 0.0023 17.7 0.0 2.5 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Hira PF07569.11 EEQ37523.1 - 0.001 18.9 2.8 2.9 7.6 0.1 4.7 4 1 1 5 5 5 1 TUP1-like enhancer of split WD40_like PF17005.5 EEQ37523.1 - 0.019 14.3 0.0 7.7 5.7 0.0 4.0 5 1 1 6 6 6 0 WD40-like domain Nbas_N PF15492.6 EEQ37523.1 - 0.052 12.9 0.0 0.52 9.6 0.0 2.7 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal ABC1 PF03109.16 EEQ37524.1 - 1.3e-24 86.7 0.1 5.1e-24 84.7 0.1 2.1 2 0 0 2 2 2 1 ABC1 family Ribosomal_L2 PF00181.23 EEQ37524.1 - 0.16 12.0 0.0 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain SLS PF14611.6 EEQ37525.1 - 1e-11 45.1 0.0 2.3e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Pro_dh PF01619.18 EEQ37526.1 - 1.6e-62 211.7 0.2 2.1e-62 211.3 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase IlvC PF01450.19 EEQ37526.1 - 0.084 13.2 0.6 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain LINES_C PF14695.6 EEQ37526.1 - 3.9 7.0 5.2 0.7 9.4 0.4 2.3 3 0 0 3 3 3 0 Lines C-terminus Rad9_Rad53_bind PF08605.10 EEQ37527.1 - 4.7e-19 68.9 0.0 1.1e-18 67.7 0.0 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 EEQ37527.1 - 1.9e-07 31.4 0.1 2.7e-06 27.6 0.0 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EEQ37527.1 - 5.8e-06 26.6 1.6 3.7e-05 24.1 0.1 3.1 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_6 PF16771.5 EEQ37527.1 - 0.078 13.1 0.1 0.49 10.6 0.1 2.4 1 1 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain TFIIS_M PF07500.14 EEQ37528.1 - 5.9e-14 52.5 0.7 1.8e-13 51.0 0.2 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 EEQ37528.1 - 1.8e-08 34.5 0.3 2.6e-07 30.7 0.0 2.8 3 1 0 3 3 3 1 SPOC domain PHD PF00628.29 EEQ37528.1 - 2.3e-08 33.8 7.1 6.5e-08 32.4 7.1 1.8 1 1 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEQ37528.1 - 0.0049 16.4 3.2 0.0049 16.4 3.2 1.9 2 0 0 2 2 2 1 PHD-finger zf-DNL PF05180.12 EEQ37528.1 - 0.065 13.2 3.3 3.6 7.6 0.6 2.6 2 0 0 2 2 2 0 DNL zinc finger Pept_S41_N PF18294.1 EEQ37528.1 - 0.14 12.2 0.6 2.8 8.0 0.1 2.9 2 0 0 2 2 2 0 Peptidase S41 N-terminal domain PHD_4 PF16866.5 EEQ37528.1 - 0.21 11.7 7.3 0.69 10.0 7.3 1.9 1 0 0 1 1 1 0 PHD-finger HypA PF01155.19 EEQ37528.1 - 1.3 9.0 6.4 17 5.5 6.4 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TMEMspv1-c74-12 PF11044.8 EEQ37528.1 - 4.5 7.3 4.5 13 5.8 4.5 1.8 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein zf-CSL PF05207.13 EEQ37528.1 - 6.3 6.6 8.2 9.4 6.1 3.7 2.5 1 1 1 2 2 2 0 CSL zinc finger CRF1 PF10380.9 EEQ37529.1 - 2.3e-26 92.3 1.4 2e-25 89.4 1.4 2.7 1 0 0 1 1 1 1 Transcription factor CRF1 GDA1_CD39 PF01150.17 EEQ37530.1 - 2.1e-113 379.2 0.0 2.8e-113 378.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family NAD_kinase PF01513.21 EEQ37532.1 - 6.7e-36 124.0 0.0 8.6e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EEQ37532.1 - 0.0028 17.3 0.0 0.0064 16.1 0.0 1.5 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EEQ37533.1 - 1.5e-32 113.0 0.2 2.1e-32 112.5 0.2 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DEAD PF00270.29 EEQ37534.1 - 4.7e-46 156.7 0.0 2.5e-45 154.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ37534.1 - 1.1e-31 109.4 0.0 5.1e-31 107.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ37534.1 - 0.093 12.7 0.0 0.31 11.0 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Gly_transf_sug PF04488.15 EEQ37535.1 - 3e-15 56.6 0.1 6.8e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EEQ37535.1 - 0.0006 19.3 2.4 0.0012 18.3 2.3 1.6 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein Sigma_reg_N PF13800.6 EEQ37535.1 - 0.096 13.0 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Isochorismatase PF00857.20 EEQ37536.1 - 1.6e-22 80.5 2.1 8.4e-22 78.2 2.1 2.0 1 1 0 1 1 1 1 Isochorismatase family Isy1 PF06246.12 EEQ37537.1 - 1.8e-50 171.9 3.4 5.7e-47 160.4 1.4 2.0 1 1 1 2 2 2 2 Isy1-like splicing family ZapB PF06005.12 EEQ37537.1 - 0.03 14.8 0.1 0.1 13.1 0.1 1.8 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 EEQ37537.1 - 0.093 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Septum formation initiator NUC153 PF08159.12 EEQ37538.1 - 3.9e-14 52.2 0.9 9.5e-14 50.9 0.9 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EEQ37538.1 - 4.5e-05 24.1 0.2 0.59 11.1 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat DUF5347 PF17282.2 EEQ37538.1 - 0.55 10.6 5.8 2.3 8.6 5.8 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5347) Lyase_1 PF00206.20 EEQ37540.1 - 5.9e-100 334.7 0.0 9.8e-100 333.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EEQ37540.1 - 5.7e-22 78.3 0.0 1.2e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal tRNA-synt_2 PF00152.20 EEQ37541.1 - 1.4e-92 310.1 0.0 2.2e-92 309.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ37541.1 - 7e-13 48.4 0.1 1.3e-12 47.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 EEQ37541.1 - 0.015 14.8 0.0 0.044 13.3 0.0 1.7 1 1 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ras_bdg_2 PF14847.6 EEQ37541.1 - 0.25 11.7 1.5 0.52 10.7 1.5 1.5 1 0 0 1 1 1 0 Ras-binding domain of Byr2 ProRS-C_1 PF09180.11 EEQ37542.1 - 6.9e-25 87.1 1.8 1.5e-24 86.0 1.8 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EEQ37542.1 - 2e-19 69.5 0.0 6e-19 68.0 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EEQ37542.1 - 1.7e-18 67.2 0.0 3.3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 EEQ37542.1 - 2.1e-05 24.6 0.7 3.6e-05 23.9 0.7 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Ribosomal_60s PF00428.19 EEQ37542.1 - 0.97 10.1 13.0 2.8 8.6 4.9 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein PHP PF02811.19 EEQ37543.1 - 6e-13 49.4 0.1 1.2e-12 48.5 0.1 1.4 1 0 0 1 1 1 1 PHP domain tRNA-synt_2 PF00152.20 EEQ37544.1 - 9e-81 271.4 0.0 1.2e-80 270.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ37544.1 - 6e-07 29.4 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 EEQ37544.1 - 0.014 15.3 0.0 0.12 12.4 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EEQ37544.1 - 0.056 12.9 0.0 1.9 7.9 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 EEQ37545.1 - 1.6e-21 75.7 6.3 2.3e-21 75.2 6.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 EEQ37545.1 - 0.011 16.0 0.0 0.12 12.7 0.1 2.0 1 1 1 2 2 2 0 Phasin protein Hormone_recep PF00104.30 EEQ37545.1 - 0.033 13.8 2.8 0.038 13.6 2.8 1.2 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor Tam41_Mmp37 PF09139.11 EEQ37545.1 - 0.051 13.0 0.7 0.054 12.9 0.7 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial Bromodomain PF00439.25 EEQ37546.1 - 8.6e-12 45.0 0.1 1.8e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 Bromodomain RR_TM4-6 PF06459.12 EEQ37546.1 - 9.9 5.9 18.9 16 5.2 18.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.16 EEQ37547.1 - 1.3e-16 60.5 40.5 1e-08 34.5 13.3 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF4131 PF13567.6 EEQ37547.1 - 7 6.3 16.1 6.7 6.3 0.0 4.6 4 2 1 5 5 5 0 Domain of unknown function (DUF4131) OppC_N PF12911.7 EEQ37547.1 - 9.1 6.3 7.9 3.8 7.6 0.3 3.4 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Aminotran_3 PF00202.21 EEQ37548.1 - 5.7e-70 236.0 0.0 6.4e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III FMN_dh PF01070.18 EEQ37549.1 - 8.9e-93 311.1 0.0 1.3e-92 310.6 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EEQ37549.1 - 1.3e-21 76.5 0.0 2.8e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EEQ37549.1 - 4.3e-10 39.3 0.0 7.5e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EEQ37549.1 - 1.7e-05 24.0 0.7 6.3e-05 22.1 0.3 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EEQ37549.1 - 0.0069 15.8 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.21 EEQ37549.1 - 0.028 13.9 0.2 3.1 7.2 0.0 2.8 3 0 0 3 3 3 0 Histidine biosynthesis protein Actin PF00022.19 EEQ37549.1 - 0.037 12.7 0.0 0.058 12.0 0.0 1.2 1 0 0 1 1 1 0 Actin Ribul_P_3_epim PF00834.19 EEQ37549.1 - 0.086 12.2 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family Glu_syn_central PF04898.14 EEQ37549.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain AA_permease PF00324.21 EEQ37550.1 - 7.4e-105 351.3 42.9 9e-105 351.0 42.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ37550.1 - 1.9e-21 76.4 46.8 3.1e-21 75.7 46.8 1.3 1 1 0 1 1 1 1 Amino acid permease DUF3464 PF11947.8 EEQ37550.1 - 4.4 7.0 7.7 20 4.9 3.8 2.7 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 ApbA_C PF08546.11 EEQ37551.1 - 3.3e-30 104.8 0.0 8e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EEQ37551.1 - 1.4e-26 93.0 0.0 1.9e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 EEQ37551.1 - 0.11 13.2 0.2 0.25 12.0 0.2 1.6 1 0 0 1 1 1 0 PglD N-terminal domain Fungal_trans_2 PF11951.8 EEQ37552.1 - 8.6e-48 163.1 1.8 1.2e-47 162.6 1.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mod_r PF07200.13 EEQ37552.1 - 0.072 13.2 0.2 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Band_7 PF01145.25 EEQ37553.1 - 1.6e-34 119.5 1.5 2.6e-34 118.8 1.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EEQ37553.1 - 0.00019 21.2 0.1 0.00029 20.6 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Gasdermin PF04598.12 EEQ37554.1 - 0.0053 16.2 0.5 0.006 16.0 0.5 1.2 1 0 0 1 1 1 1 Gasdermin pore forming domain DUF2040 PF09745.9 EEQ37554.1 - 0.0063 16.6 4.4 0.0063 16.6 4.4 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Synaphin PF05835.12 EEQ37554.1 - 0.045 14.0 1.2 0.045 14.0 1.2 2.2 1 1 1 2 2 2 0 Synaphin protein DUF334 PF03904.13 EEQ37554.1 - 0.4 10.2 4.6 0.49 9.9 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) DTHCT PF08070.11 EEQ37554.1 - 1.3 9.8 13.0 2.1 9.1 8.0 2.8 1 1 1 2 2 2 0 DTHCT (NUC029) region DUF1720 PF08226.11 EEQ37555.1 - 0.0093 16.4 0.3 0.0093 16.4 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1720) Corazonin PF17308.2 EEQ37555.1 - 0.066 13.6 4.9 0.15 12.4 4.9 1.6 1 0 0 1 1 1 0 Pro-corazonin Secretin_N_2 PF07655.13 EEQ37555.1 - 8.9 6.9 14.5 0.81 10.3 8.2 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Pkinase PF00069.25 EEQ37556.1 - 8.9e-72 241.6 0.0 1.3e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37556.1 - 1.5e-48 165.4 0.0 2.8e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EEQ37556.1 - 1.8e-19 69.9 0.1 5.8e-19 68.2 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EEQ37556.1 - 0.00021 20.7 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ37556.1 - 0.00025 20.0 0.0 0.00025 20.0 0.0 2.4 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EEQ37556.1 - 0.03 14.3 0.0 0.8 9.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sas6_CC PF18594.1 EEQ37556.1 - 0.061 13.1 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Sas6/XLF/XRCC4 coiled-coil domain Haspin_kinase PF12330.8 EEQ37556.1 - 0.074 12.0 0.5 0.14 11.1 0.3 1.6 1 1 0 1 1 1 0 Haspin like kinase domain DUF3484 PF11983.8 EEQ37556.1 - 0.24 12.6 0.1 0.24 12.6 0.1 4.7 4 3 0 4 4 4 0 Membrane-attachment and polymerisation-promoting switch MT-A70 PF05063.14 EEQ37558.1 - 2.2e-10 40.7 0.0 1.5e-09 38.0 0.0 2.1 1 1 0 1 1 1 1 MT-A70 DUF3408 PF11888.8 EEQ37558.1 - 0.1 12.7 3.8 0.2 11.8 3.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Iso_dh PF00180.20 EEQ37559.1 - 1.1e-74 251.7 0.0 1.3e-74 251.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase mRNA_triPase PF02940.15 EEQ37560.1 - 6.1e-58 196.1 5.0 6.1e-58 196.1 5.0 1.9 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.26 EEQ37561.1 - 1.3e-26 93.4 0.0 1.6e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EEQ37561.1 - 2.3e-12 47.3 0.0 3.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EEQ37561.1 - 0.0001 22.7 0.0 0.00022 21.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EEQ37561.1 - 0.0027 17.2 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Pyr_redox_2 PF07992.14 EEQ37562.1 - 3.4e-65 220.2 6.7 5e-65 219.6 6.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EEQ37562.1 - 7.9e-42 142.0 2.0 2.7e-41 140.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EEQ37562.1 - 1.8e-20 73.3 7.2 3.1e-18 66.1 2.2 3.4 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ37562.1 - 1.6e-09 37.9 2.1 0.0017 18.5 0.1 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EEQ37562.1 - 3.4e-09 36.3 6.9 3.4e-08 33.0 0.4 2.7 2 1 1 3 3 3 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EEQ37562.1 - 2.6e-08 33.5 2.7 4.8e-06 26.0 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEQ37562.1 - 9.2e-06 25.3 6.7 9.1e-05 22.0 0.1 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 EEQ37562.1 - 5.7e-05 22.5 3.1 0.011 14.9 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 EEQ37562.1 - 0.00052 18.8 10.7 0.031 13.0 0.2 4.2 5 0 0 5 5 5 2 HI0933-like protein AlaDh_PNT_C PF01262.21 EEQ37562.1 - 0.00094 18.5 2.7 0.0028 17.0 0.4 2.5 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EEQ37562.1 - 0.0013 18.6 1.2 0.0047 16.8 1.2 2.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EEQ37562.1 - 0.0016 17.6 0.1 1 8.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EEQ37562.1 - 0.0017 17.5 0.2 0.0017 17.5 0.2 2.3 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 EEQ37562.1 - 0.0093 15.6 11.5 0.057 13.0 1.7 3.5 3 1 1 4 4 4 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EEQ37562.1 - 0.032 13.5 4.9 0.37 10.0 1.5 2.6 2 1 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 EEQ37562.1 - 0.033 13.8 0.5 0.033 13.8 0.5 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.17 EEQ37562.1 - 0.076 13.6 4.0 5.3 7.7 2.9 3.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 EEQ37562.1 - 0.18 10.8 1.0 8 5.4 0.3 2.4 2 0 0 2 2 2 0 Lycopene cyclase protein Pmp3 PF01679.17 EEQ37564.1 - 1.5e-22 79.5 10.3 1.6e-22 79.4 10.3 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Phage_holin_Dp1 PF16938.5 EEQ37564.1 - 0.12 12.6 2.2 0.59 10.4 2.2 1.9 1 1 0 1 1 1 0 Putative phage holin Dp-1 DUF818 PF05677.12 EEQ37564.1 - 0.98 8.3 3.0 0.92 8.4 3.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF872 PF05915.12 EEQ37564.1 - 3.4 7.9 5.8 4.1 7.6 5.8 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) tRNA-synt_2d PF01409.20 EEQ37565.1 - 4.6e-88 294.8 0.0 6e-88 294.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EEQ37565.1 - 7.3e-15 55.0 0.4 7.3e-15 55.0 0.4 2.5 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EEQ37565.1 - 7.5e-09 35.3 0.0 9.8e-08 31.7 0.0 2.1 1 1 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 EEQ37565.1 - 3.7e-05 23.8 0.0 7e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 EEQ37565.1 - 7.2e-05 22.7 1.8 0.00018 21.4 1.8 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 EEQ37565.1 - 9.1e-05 21.7 0.1 0.002 17.3 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) DUF1642 PF07852.11 EEQ37565.1 - 0.071 13.7 0.8 0.14 12.8 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Rio2_N PF09202.11 EEQ37565.1 - 0.14 12.4 0.1 7.9 6.8 0.0 2.6 2 0 0 2 2 2 0 Rio2, N-terminal zf-H2C2_2 PF13465.6 EEQ37566.1 - 5.4e-06 26.6 3.7 5.4e-06 26.6 3.7 2.2 2 0 0 2 2 2 1 Zinc-finger double domain FOXP-CC PF16159.5 EEQ37566.1 - 0.00013 22.5 11.2 0.12 13.0 0.1 3.6 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2 PF00096.26 EEQ37566.1 - 0.0028 18.0 0.3 0.0028 18.0 0.3 3.3 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ37566.1 - 0.0035 18.1 8.0 0.039 14.8 0.4 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EEQ37566.1 - 0.081 13.6 3.3 2.4 8.8 0.1 3.1 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats Chromo PF00385.24 EEQ37566.1 - 0.086 12.8 0.0 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain zf-C2H2_aberr PF17017.5 EEQ37566.1 - 0.13 12.4 1.1 10 6.2 0.1 2.5 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 EEQ37566.1 - 1.4 9.3 3.5 0.85 10.0 0.9 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zap1_zf2 PF18217.1 EEQ37566.1 - 5.5 7.1 9.6 1.5 8.9 2.6 2.9 2 1 0 2 2 2 0 Zap1 zinc finger 2 Fcf2 PF08698.11 EEQ37567.1 - 2.3e-36 124.1 1.9 2.3e-36 124.1 1.9 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing ABC_tran_CTD PF16326.5 EEQ37567.1 - 0.0028 17.9 1.8 0.019 15.2 0.9 2.4 2 0 0 2 2 2 1 ABC transporter C-terminal domain Prominin PF05478.11 EEQ37567.1 - 0.3 9.0 1.7 0.36 8.7 1.7 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 EEQ37567.1 - 0.36 10.9 2.9 0.76 9.8 2.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FadA PF09403.10 EEQ37567.1 - 1.4 9.4 9.4 1 9.9 0.2 2.9 2 1 1 3 3 3 0 Adhesion protein FadA STD1 PF17235.2 EEQ37568.1 - 6.5e-54 182.7 5.7 6.5e-54 182.7 5.7 1.7 1 1 1 2 2 2 1 STD1/MTH1 PBS_linker_poly PF00427.21 EEQ37568.1 - 0.019 15.0 2.5 0.36 10.9 0.0 3.0 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide PGBA_C PF15437.6 EEQ37568.1 - 0.028 14.8 3.1 0.062 13.7 3.1 1.6 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal Mlf1IP PF10248.9 EEQ37568.1 - 0.28 11.1 2.2 0.5 10.3 2.2 1.3 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein NUP214 PF16755.5 EEQ37569.1 - 9e-19 67.9 0.1 2.9e-18 66.3 0.1 1.8 1 1 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 CAP_GLY PF01302.25 EEQ37570.1 - 2.8e-14 52.9 0.1 5.3e-14 52.0 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain MscS_porin PF12795.7 EEQ37570.1 - 1.1e-05 25.1 24.1 1.1e-05 25.1 24.1 4.3 1 1 2 3 3 3 1 Mechanosensitive ion channel porin domain Filament PF00038.21 EEQ37570.1 - 0.026 14.1 78.3 0.056 13.0 13.8 4.3 2 1 2 4 4 4 0 Intermediate filament protein AAA_13 PF13166.6 EEQ37570.1 - 0.17 10.5 63.4 0.058 12.0 24.8 3.2 1 1 2 3 3 3 0 AAA domain Spc7 PF08317.11 EEQ37570.1 - 0.19 10.6 89.0 0.15 11.0 10.1 5.3 1 1 4 5 5 5 0 Spc7 kinetochore protein Dynamitin PF04912.14 EEQ37570.1 - 7.3 5.8 76.3 3.9 6.7 33.1 4.0 1 1 3 4 4 4 0 Dynamitin SF3b10 PF07189.11 EEQ37571.1 - 5.7e-31 106.5 0.2 6.8e-31 106.2 0.2 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) GATA PF00320.27 EEQ37572.1 - 7.3e-15 54.3 3.7 1.5e-14 53.3 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EEQ37572.1 - 7.1e-05 22.6 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Elf1 PF05129.13 EEQ37572.1 - 0.017 15.2 0.1 0.047 13.8 0.1 1.7 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like CCDC84 PF14968.6 EEQ37572.1 - 0.027 14.1 4.4 0.04 13.6 4.4 1.4 1 0 0 1 1 1 0 Coiled coil protein 84 TF_Zn_Ribbon PF08271.12 EEQ37572.1 - 0.053 13.0 1.5 0.1 12.1 1.5 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 EEQ37572.1 - 0.17 12.1 0.8 0.27 11.4 0.8 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) NinE PF05322.11 EEQ37572.1 - 0.2 11.6 0.5 0.82 9.6 0.0 2.3 3 0 0 3 3 3 0 NINE Protein Cytochrome_C7 PF14522.6 EEQ37572.1 - 0.24 11.4 3.0 0.55 10.3 3.0 1.6 1 0 0 1 1 1 0 Cytochrome c7 and related cytochrome c BBP1_C PF15272.6 EEQ37572.1 - 0.46 10.3 2.1 0.85 9.4 0.1 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Sel1 PF08238.12 EEQ37573.1 - 5.6e-12 45.9 6.2 4.6e-05 23.9 0.0 6.2 6 1 0 6 6 6 2 Sel1 repeat TPR_17 PF13431.6 EEQ37573.1 - 0.0062 16.8 0.7 0.13 12.7 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat PRIMA1 PF16101.5 EEQ37573.1 - 6.2 6.9 6.1 4.3 7.4 1.1 2.7 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 TPR_2 PF07719.17 EEQ37573.1 - 9.6 6.6 11.1 64 4.0 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat eIF2A PF08662.11 EEQ37574.1 - 2.6e-77 259.1 0.0 5.6e-77 258.0 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Enkurin PF13864.6 EEQ37574.1 - 0.11 13.0 2.3 0.21 12.1 2.3 1.3 1 0 0 1 1 1 0 Calmodulin-binding WD40 PF00400.32 EEQ37574.1 - 0.15 13.0 0.2 6.1 7.9 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat FKS1_dom1 PF14288.6 EEQ37575.1 - 3.8e-42 143.7 0.4 1.1e-41 142.1 0.4 1.8 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 HIN PF02760.15 EEQ37576.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 HIN-200/IF120x domain ALMT PF11744.8 EEQ37577.1 - 0.28 10.0 6.3 0.32 9.8 6.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Glucan_synthase PF02364.15 EEQ37578.1 - 2.2e-194 648.0 3.9 2.2e-194 648.0 3.9 1.4 2 0 0 2 2 2 1 1,3-beta-glucan synthase component DUF3817 PF12823.7 EEQ37578.1 - 0.02 15.7 5.0 0.02 15.7 5.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) DUF3671 PF12420.8 EEQ37578.1 - 0.093 12.8 0.2 0.093 12.8 0.2 2.8 4 0 0 4 4 4 0 Protein of unknown function Glyco_transf_34 PF05637.12 EEQ37580.1 - 2e-48 165.2 2.2 2.9e-48 164.7 2.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF1751 PF08551.10 EEQ37581.1 - 1.3e-22 80.3 4.1 1.3e-22 80.3 4.1 2.1 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EEQ37581.1 - 0.0073 16.3 11.9 0.014 15.4 11.9 1.5 1 0 0 1 1 1 1 Rhomboid family Phageshock_PspG PF09583.10 EEQ37581.1 - 0.073 13.4 0.9 0.073 13.4 0.9 3.1 3 0 0 3 3 3 0 Phage shock protein G (Phageshock_PspG) DRMBL PF07522.14 EEQ37582.1 - 4.1e-20 72.0 0.0 9e-20 70.9 0.0 1.6 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase ACI44 PF15270.6 EEQ37582.1 - 0.14 12.4 1.7 0.25 11.5 0.2 2.1 2 0 0 2 2 2 0 Metallo-carboxypeptidase inhibitor Arf PF00025.21 EEQ37583.1 - 1.3e-48 164.8 0.5 1.5e-48 164.5 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEQ37583.1 - 2.7e-12 47.0 0.1 3.8e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EEQ37583.1 - 4.7e-12 45.7 3.7 4e-08 32.8 1.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EEQ37583.1 - 2.8e-11 43.2 0.1 3.3e-11 43.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEQ37583.1 - 1.8e-08 34.2 0.1 2.3e-07 30.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.22 EEQ37583.1 - 2.1e-08 34.0 0.0 2.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EEQ37583.1 - 1.5e-06 28.3 0.0 2.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 EEQ37583.1 - 0.00037 20.1 0.2 0.011 15.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EEQ37583.1 - 0.0013 18.2 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EEQ37583.1 - 0.0082 16.1 0.1 0.33 10.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EEQ37583.1 - 0.046 13.2 0.3 0.25 10.8 0.3 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B TIM21 PF08294.11 EEQ37585.1 - 3.9e-43 146.8 0.0 5.5e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 TIM21 PRIMA1 PF16101.5 EEQ37585.1 - 0.032 14.3 0.8 0.06 13.4 0.8 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 6PF2K PF01591.18 EEQ37586.1 - 1.1e-60 204.7 0.1 1.6e-60 204.2 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEQ37586.1 - 1.5e-14 54.1 0.0 5.4e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EEQ37586.1 - 0.031 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ37586.1 - 0.033 14.7 0.0 0.08 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3829 PF12889.7 EEQ37586.1 - 0.046 13.2 1.4 0.065 12.7 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Katanin_con80 PF13925.6 EEQ37586.1 - 0.088 12.8 0.0 0.22 11.5 0.0 1.6 2 0 0 2 2 2 0 con80 domain of Katanin IstB_IS21 PF01695.17 EEQ37586.1 - 0.092 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein tRNA_lig_kinase PF08303.11 EEQ37586.1 - 0.14 12.2 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain Gon7 PF08738.10 EEQ37587.1 - 3.8e-28 97.7 0.0 4.7e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 Gon7 family CCD PF07860.11 EEQ37587.1 - 0.01 15.9 0.1 0.012 15.7 0.1 1.2 1 0 0 1 1 1 0 WisP family C-Terminal Region Prefoldin_2 PF01920.20 EEQ37588.1 - 2e-12 47.0 4.9 2.4e-12 46.7 4.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Baculo_PEP_C PF04513.12 EEQ37588.1 - 0.07 13.2 4.3 0.76 9.8 1.4 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EEQ37588.1 - 0.15 12.4 2.3 0.63 10.3 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) KxDL PF10241.9 EEQ37588.1 - 0.17 12.2 4.1 1.3 9.4 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein FapA PF03961.13 EEQ37588.1 - 0.6 8.7 7.2 2.3 6.7 7.2 1.8 1 1 0 1 1 1 0 Flagellar Assembly Protein A ATP12 PF07542.11 EEQ37589.1 - 2.3e-31 108.6 0.0 3.7e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein SMK-1 PF04802.15 EEQ37590.1 - 1.3e-57 194.7 9.4 1.4e-57 194.7 5.8 2.5 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 WH1 PF00568.23 EEQ37590.1 - 0.0024 17.8 0.0 0.0058 16.5 0.0 1.7 1 0 0 1 1 1 1 WH1 domain adh_short_C2 PF13561.6 EEQ37591.1 - 1.4e-42 145.9 0.8 1.7e-42 145.6 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ37591.1 - 1.8e-35 122.2 0.6 2.3e-35 121.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ37591.1 - 4e-11 43.2 0.6 5.6e-11 42.7 0.6 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ37591.1 - 0.12 11.9 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ArfGap PF01412.18 EEQ37592.1 - 6.6e-32 110.0 0.0 1.5e-31 108.9 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Herpes_UL6 PF01763.16 EEQ37592.1 - 0.22 10.0 0.1 0.31 9.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like PAP2 PF01569.21 EEQ37593.1 - 3.8e-16 59.1 3.9 3.8e-16 59.1 3.9 1.4 2 0 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EEQ37593.1 - 0.28 11.3 2.8 2.6 8.2 0.2 2.2 1 1 1 2 2 2 0 Divergent PAP2 family DUF543 PF04418.12 EEQ37593.1 - 2.5 8.1 4.2 2.2 8.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) IFRD PF05004.13 EEQ37595.1 - 0.0083 15.3 2.3 0.011 14.8 2.3 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DRIM PF07539.12 EEQ37595.1 - 0.0099 14.2 2.3 0.015 13.6 2.3 1.4 1 1 0 1 1 1 1 Down-regulated in metastasis RIX1 PF08167.12 EEQ37595.1 - 0.017 14.9 0.3 0.05 13.4 0.3 1.8 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis DUF1804 PF08822.11 EEQ37595.1 - 0.038 14.0 0.5 5 7.1 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1804) Telomere_reg-2 PF10193.9 EEQ37595.1 - 0.045 14.2 1.2 3 8.3 0.2 2.2 1 1 1 2 2 2 0 Telomere length regulation protein DUF4455 PF14643.6 EEQ37595.1 - 0.073 11.7 0.8 0.085 11.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) Bep_C_terminal PF17841.1 EEQ37596.1 - 0.0007 19.8 4.5 0.0012 19.0 4.5 1.4 1 0 0 1 1 1 1 BID domain of Bartonella effector protein (Bep) Synaptobrevin PF00957.21 EEQ37596.1 - 0.049 13.4 7.9 0.1 12.4 4.1 2.4 1 1 1 2 2 2 0 Synaptobrevin Fmp27_WPPW PF10359.9 EEQ37596.1 - 0.67 8.7 16.3 0.33 9.7 14.2 1.4 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Exonuc_VII_L PF02601.15 EEQ37596.1 - 0.77 9.3 8.3 1 8.8 8.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4570 PF15134.6 EEQ37596.1 - 1.2 9.1 17.2 0.11 12.5 8.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) DUF3552 PF12072.8 EEQ37596.1 - 4 6.8 24.8 1.7 8.0 20.8 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF3552) V_ATPase_I PF01496.19 EEQ37596.1 - 9.8 4.0 12.8 11 3.7 12.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Septin PF00735.18 EEQ37597.1 - 5.6e-67 226.0 4.7 6.7e-66 222.4 4.7 1.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EEQ37597.1 - 1.7e-07 31.3 0.0 4e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ37597.1 - 2.9e-07 30.2 0.2 9.9e-06 25.2 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ37597.1 - 5.7e-06 26.3 0.6 6.5e-05 22.9 0.4 2.5 2 1 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EEQ37597.1 - 1.9e-05 24.8 0.1 0.00053 20.1 0.1 2.3 1 1 0 1 1 1 1 Dynamin family AIG1 PF04548.16 EEQ37597.1 - 0.00062 19.2 0.5 0.21 10.9 0.3 2.4 1 1 1 2 2 2 2 AIG1 family IIGP PF05049.13 EEQ37597.1 - 0.0025 17.0 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EEQ37597.1 - 0.0031 17.2 0.0 0.008 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ37597.1 - 0.0086 16.3 0.1 0.026 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 EEQ37597.1 - 0.015 14.7 0.1 0.074 12.4 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 EEQ37597.1 - 0.015 15.5 0.1 0.46 10.7 0.2 2.3 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EEQ37597.1 - 0.017 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 EEQ37597.1 - 0.024 14.2 0.2 0.08 12.5 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_7 PF12775.7 EEQ37597.1 - 0.029 13.9 0.2 0.054 13.0 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EEQ37597.1 - 0.031 14.8 0.1 0.067 13.7 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Ras PF00071.22 EEQ37597.1 - 0.041 13.5 0.3 4.6 6.8 0.2 2.4 1 1 1 2 2 2 0 Ras family dNK PF01712.19 EEQ37597.1 - 0.044 13.6 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_16 PF13191.6 EEQ37597.1 - 0.049 14.0 0.0 0.077 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 EEQ37597.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain YjeF_N PF03853.15 EEQ37598.1 - 6.5e-38 130.3 0.0 8e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus APG5 PF04106.12 EEQ37600.1 - 2.1e-43 148.5 0.1 2.7e-43 148.2 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Methyltransf_23 PF13489.6 EEQ37601.1 - 8.1e-18 64.8 0.0 1.1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ37601.1 - 2.9e-16 60.0 0.3 1.3e-15 58.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ37601.1 - 7e-14 52.3 0.0 1.7e-13 51.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ37601.1 - 2.5e-12 47.3 0.0 5.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ37601.1 - 1.2e-08 34.9 0.0 5.5e-08 32.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ37601.1 - 8.8e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EEQ37601.1 - 0.00093 18.5 0.0 0.9 8.7 0.0 2.1 2 0 0 2 2 2 2 NNMT/PNMT/TEMT family MTS PF05175.14 EEQ37601.1 - 0.00093 18.8 0.0 0.0025 17.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EEQ37601.1 - 0.0014 18.0 0.0 0.0038 16.6 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 EEQ37601.1 - 0.0052 16.5 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 EEQ37601.1 - 0.0087 15.5 0.3 0.065 12.6 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TehB PrmA PF06325.13 EEQ37601.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 EEQ37601.1 - 0.079 14.0 0.0 0.14 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.11 EEQ37601.1 - 0.1 12.2 0.0 0.32 10.6 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Sybindin PF04099.12 EEQ37602.1 - 5.4e-38 130.1 1.7 8e-36 123.1 1.7 2.1 1 1 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EEQ37602.1 - 6.8e-11 42.4 0.1 8.7e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region IPPT PF01715.17 EEQ37603.1 - 9.7e-63 212.0 0.1 1.4e-62 211.5 0.1 1.2 1 0 0 1 1 1 1 IPP transferase AAA_18 PF13238.6 EEQ37603.1 - 0.02 15.4 0.9 0.046 14.3 0.2 2.0 2 1 0 2 2 2 0 AAA domain BRO1 PF03097.18 EEQ37604.1 - 1.3e-90 304.0 4.8 2.3e-90 303.2 3.9 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EEQ37604.1 - 2.7e-66 223.9 6.6 3.2e-66 223.6 3.3 2.3 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV MSG PF02349.15 EEQ37604.1 - 0.31 11.2 3.8 6.2 7.1 0.1 3.2 3 0 0 3 3 3 0 Major surface glycoprotein Myb_DNA-binding PF00249.31 EEQ37605.1 - 3e-25 88.2 1.1 2.5e-11 43.6 0.1 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ37605.1 - 1.9e-22 79.2 2.1 2e-11 44.0 0.1 3.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EEQ37605.1 - 0.01 15.9 0.1 4 7.6 0.0 3.7 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain EntA_Immun PF08951.10 EEQ37605.1 - 0.062 13.7 3.2 3.6 8.0 0.5 3.6 2 1 1 3 3 3 0 Enterocin A Immunity DUF5641 PF18701.1 EEQ37605.1 - 0.18 12.0 6.5 6.5 7.0 0.8 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5641) Ku_PK_bind PF08785.11 EEQ37605.1 - 0.21 11.7 6.0 0.089 12.9 1.6 2.7 3 0 0 3 3 3 0 Ku C terminal domain like SANT_DAMP1_like PF16282.5 EEQ37605.1 - 0.37 11.0 2.4 0.95 9.7 0.1 2.7 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 tRNA-synt_1e PF01406.19 EEQ37605.1 - 0.82 9.0 4.4 2.4 7.4 4.4 2.0 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Clathrin_propel PF01394.20 EEQ37607.1 - 1e-17 63.4 0.1 3.3e-05 24.0 0.0 3.3 3 0 0 3 3 3 3 Clathrin propeller repeat Clathrin PF00637.20 EEQ37608.1 - 1.8e-37 128.4 9.5 6.5e-20 71.5 3.1 3.0 3 0 0 3 3 3 3 Region in Clathrin and VPS Clathrin PF00637.20 EEQ37609.1 - 4.5e-121 399.4 26.1 4.1e-32 111.0 1.4 5.1 5 0 0 5 5 5 4 Region in Clathrin and VPS PPR PF01535.20 EEQ37609.1 - 0.00035 20.6 0.8 31 5.1 0.1 5.8 6 0 0 6 6 6 0 PPR repeat TPR_2 PF07719.17 EEQ37609.1 - 0.00045 20.1 3.3 5.8 7.3 0.0 6.0 5 1 1 6 6 6 1 Tetratricopeptide repeat Vps39_1 PF10366.9 EEQ37609.1 - 0.0014 18.9 11.2 1.5 9.1 0.1 6.3 5 2 2 7 7 7 1 Vacuolar sorting protein 39 domain 1 TPR_1 PF00515.28 EEQ37609.1 - 0.0066 16.2 5.7 13 5.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ37609.1 - 0.03 14.6 0.6 30 5.0 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ37609.1 - 0.058 13.4 3.1 12 6.2 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ37609.1 - 0.17 12.1 2.4 5.8 7.2 0.0 4.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EEQ37609.1 - 2 8.8 8.4 68 4.1 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat CENP-O PF09496.10 EEQ37610.1 - 1.5e-21 77.4 0.1 2.7e-21 76.6 0.1 1.5 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component WSC PF01822.19 EEQ37611.1 - 4.3e-10 39.6 9.7 4.3e-10 39.6 9.7 3.3 3 1 0 3 3 3 1 WSC domain PPI_Ypi1 PF07491.11 EEQ37612.1 - 3.6e-26 90.8 13.6 3.6e-26 90.8 13.6 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor IRF PF00605.17 EEQ37612.1 - 0.0084 16.4 0.9 0.011 16.0 0.9 1.2 1 0 0 1 1 1 1 Interferon regulatory factor transcription factor Atrophin-1 PF03154.15 EEQ37612.1 - 0.13 10.6 9.7 0.14 10.4 9.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family zf-C2H2 PF00096.26 EEQ37613.1 - 4.8e-06 26.7 17.3 0.00011 22.5 3.0 4.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ37613.1 - 7.5e-05 23.0 3.2 7.5e-05 23.0 3.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ37613.1 - 0.0051 17.5 1.8 0.0051 17.5 1.8 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 EEQ37613.1 - 0.011 16.1 0.3 0.011 16.1 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ37613.1 - 0.013 15.4 0.9 0.042 13.9 0.9 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ37613.1 - 0.021 15.1 0.3 0.021 15.1 0.3 3.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding tRNA_Me_trans PF03054.16 EEQ37614.1 - 5.9e-116 387.1 0.0 7e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EEQ37614.1 - 0.0011 18.2 0.0 0.015 14.4 0.0 2.0 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 EEQ37614.1 - 0.0024 17.6 0.0 0.0038 17.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 EEQ37614.1 - 0.0076 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.14 EEQ37614.1 - 0.098 12.2 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) SWIRM PF04433.17 EEQ37615.1 - 1.6e-27 95.7 0.3 5.5e-27 93.9 0.1 2.1 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 EEQ37615.1 - 5.8e-08 32.8 0.0 1.4e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SWIRM-assoc_1 PF16495.5 EEQ37615.1 - 1.5e-07 31.3 5.7 3.3e-07 30.2 5.7 1.6 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-bind_6 PF13921.6 EEQ37615.1 - 0.00041 20.5 2.3 0.00075 19.7 0.1 2.6 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EEQ37615.1 - 0.056 13.8 0.4 0.19 12.1 0.1 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain GUN4 PF05419.12 EEQ37615.1 - 0.06 13.4 1.7 0.12 12.5 0.3 2.2 3 0 0 3 3 3 0 GUN4-like STAG PF08514.11 EEQ37616.1 - 1.1e-36 125.1 1.1 3.3e-36 123.6 1.1 1.8 1 0 0 1 1 1 1 STAG domain E6 PF00518.17 EEQ37616.1 - 0.13 12.7 0.7 1.3 9.4 0.2 2.6 2 0 0 2 2 2 0 Early Protein (E6) WD40 PF00400.32 EEQ37617.1 - 8.6e-20 70.7 7.3 1.9e-05 25.3 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37617.1 - 3.2e-10 40.2 0.1 0.65 10.3 0.0 5.7 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EEQ37617.1 - 0.00012 20.8 0.1 0.33 9.4 0.0 2.6 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF3g PF12353.8 EEQ37618.1 - 2.3e-42 144.3 4.3 2.9e-42 144.0 3.2 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EEQ37618.1 - 5e-15 55.1 0.0 8.1e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ37618.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EEQ37618.1 - 0.18 12.1 3.5 0.19 11.9 0.0 2.2 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Abhydrolase_3 PF07859.13 EEQ37619.1 - 4.2e-11 43.1 0.0 5.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ37619.1 - 0.00019 20.8 0.1 0.071 12.4 0.1 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EEQ37619.1 - 0.00034 20.1 0.3 0.0055 16.2 0.1 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EEQ37619.1 - 0.00053 20.7 0.0 0.00068 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EEQ37619.1 - 0.035 13.7 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase VirJ PF06057.11 EEQ37619.1 - 0.084 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Ser_hydrolase PF06821.13 EEQ37619.1 - 0.18 11.6 0.0 0.9 9.4 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase DUF3530 PF12048.8 EEQ37619.1 - 0.22 10.9 0.0 0.29 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) RRM_1 PF00076.22 EEQ37621.1 - 6.3e-21 74.0 0.0 1e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EEQ37621.1 - 0.0023 17.9 0.0 2.2 8.3 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 EEQ37621.1 - 0.0029 17.6 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EEQ37621.1 - 0.058 13.5 0.0 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 YflT PF11181.8 EEQ37621.1 - 0.065 13.8 0.0 5.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Heat induced stress protein YflT RRM_5 PF13893.6 EEQ37621.1 - 0.078 12.6 0.0 1 9.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_2 PF00703.21 EEQ37622.1 - 7.1e-14 52.4 0.6 3.4e-13 50.2 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 EEQ37622.1 - 2.3e-05 24.4 0.1 6.9e-05 22.8 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF3589 PF12141.8 EEQ37623.1 - 6.5e-110 368.0 0.2 8.5e-110 367.6 0.2 1.1 1 0 0 1 1 1 1 Beta-mannosyltransferases DUF4783 PF16022.5 EEQ37623.1 - 0.087 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) LNS2 PF08235.13 EEQ37624.1 - 4.9e-98 327.1 0.0 6.7e-98 326.7 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EEQ37624.1 - 4.1e-40 135.9 0.0 1.3e-39 134.3 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EEQ37624.1 - 0.022 14.4 0.0 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_6 PF13344.6 EEQ37624.1 - 0.053 13.6 0.0 0.36 11.0 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AA_permease_2 PF13520.6 EEQ37625.1 - 5.2e-50 170.5 55.8 6.4e-50 170.2 55.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ37625.1 - 4.5e-21 75.0 46.2 5.9e-21 74.6 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease Nic96 PF04097.14 EEQ37626.1 - 9.8e-199 661.8 3.9 1.2e-198 661.5 3.9 1.1 1 0 0 1 1 1 1 Nup93/Nic96 BET PF17035.5 EEQ37626.1 - 0.089 13.0 0.2 0.69 10.1 0.1 2.4 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation Nup_retrotrp_bd PF10599.9 EEQ37626.1 - 0.85 10.3 8.4 2.5 8.8 8.4 1.8 1 0 0 1 1 1 0 Retro-transposon transporting motif Pro_sub2 PF18513.1 EEQ37626.1 - 9.2 6.5 6.9 10 6.4 0.8 3.4 2 1 1 3 3 3 0 Prodomain subtilisin 2 Cyt-b5 PF00173.28 EEQ37627.1 - 1.3e-25 89.3 0.1 1.7e-25 89.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DnaJ PF00226.31 EEQ37628.1 - 1.1e-19 70.4 2.0 2.6e-19 69.1 0.8 2.2 2 0 0 2 2 2 1 DnaJ domain SRP68 PF16969.5 EEQ37629.1 - 1.4e-56 192.7 6.3 1.7e-56 192.4 6.3 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Pox_A32 PF04665.12 EEQ37629.1 - 0.03 13.8 0.5 0.1 12.1 0.1 2.0 2 0 0 2 2 2 0 Poxvirus A32 protein UAA PF08449.11 EEQ37630.1 - 2e-40 138.9 18.8 2.3e-40 138.7 18.8 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 EEQ37630.1 - 0.00013 21.3 10.2 0.00023 20.5 10.2 1.5 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EEQ37630.1 - 0.00017 21.7 30.8 0.0024 18.1 5.7 4.0 2 2 2 4 4 4 2 EamA-like transporter family TPT PF03151.16 EEQ37630.1 - 0.0067 15.8 15.1 0.087 12.2 3.0 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family rve PF00665.26 EEQ37631.1 - 5e-22 78.3 0.1 7.9e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EEQ37631.1 - 0.0002 21.1 0.0 0.00055 19.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EEQ37631.1 - 0.0052 16.6 0.2 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 GAG-pre-integrase domain RVT_2 PF07727.14 EEQ37632.1 - 6.4e-85 284.7 0.5 9.5e-85 284.1 0.5 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DHHC PF01529.20 EEQ37633.1 - 3.7e-34 117.7 16.5 3.7e-34 117.7 16.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DpnI_C PF17726.1 EEQ37633.1 - 0.11 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Dam-replacing HTH domain Hist_deacetyl PF00850.19 EEQ37634.1 - 1e-82 278.1 0.0 1.3e-82 277.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NAD_kinase PF01513.21 EEQ37635.1 - 3.2e-54 184.1 0.1 3.2e-54 184.1 0.1 1.7 2 0 0 2 2 2 1 ATP-NAD kinase DAGK_cat PF00781.24 EEQ37635.1 - 0.0086 15.7 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DDHD PF02862.17 EEQ37635.1 - 0.14 12.3 3.5 0.23 11.6 3.5 1.4 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 EEQ37635.1 - 2.3 6.1 6.7 3.5 5.4 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 EEQ37635.1 - 9.6 5.3 6.3 16 4.6 6.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter LysR_substrate PF03466.20 EEQ37636.1 - 0.029 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 LysR substrate binding domain Ribosomal_L7Ae PF01248.26 EEQ37637.1 - 3.8e-23 81.0 0.4 6.4e-23 80.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FliC_SP PF12613.8 EEQ37637.1 - 0.032 14.7 0.5 0.071 13.6 0.5 1.6 1 0 0 1 1 1 0 Flagellin structural protein RRM_1 PF00076.22 EEQ37638.1 - 1e-22 79.7 0.4 1.2e-11 44.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EEQ37638.1 - 0.028 14.5 0.1 0.55 10.4 0.1 2.4 2 0 0 2 2 2 0 Limkain b1 Neur_chan_memb PF02932.16 EEQ37638.1 - 0.69 9.9 8.6 0.96 9.5 0.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pox_Ag35 PF03286.14 EEQ37638.1 - 1.1 9.0 23.9 0.85 9.4 2.6 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein ABC_membrane PF00664.23 EEQ37640.1 - 2.4e-20 73.3 15.3 2.6e-20 73.2 9.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ37641.1 - 2.6e-08 34.5 0.0 3e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EEQ37642.1 - 6.5e-23 81.7 10.2 1.4e-22 80.7 10.2 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region SANTA PF09133.10 EEQ37642.1 - 0.087 13.3 0.9 0.25 11.8 0.1 2.1 2 0 0 2 2 2 0 SANTA (SANT Associated) Cep57_CLD_2 PF14197.6 EEQ37642.1 - 0.12 12.5 0.6 0.26 11.4 0.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ATG27 PF09451.10 EEQ37642.1 - 2.8 7.7 5.3 1.5 8.6 0.1 2.2 2 0 0 2 2 2 0 Autophagy-related protein 27 ABC_tran PF00005.27 EEQ37643.1 - 1e-33 116.8 0.0 1.8e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EEQ37643.1 - 1.2e-05 24.9 0.7 0.0014 18.1 0.7 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_24 PF13479.6 EEQ37643.1 - 0.00026 20.8 0.1 0.00048 19.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EEQ37643.1 - 0.00037 20.2 0.0 0.00098 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EEQ37643.1 - 0.0004 20.3 0.5 0.15 11.9 0.2 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EEQ37643.1 - 0.00096 19.7 1.2 0.0015 19.1 1.0 1.4 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EEQ37643.1 - 0.0013 18.8 0.1 0.0031 17.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ37643.1 - 0.0045 17.4 0.0 0.012 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ37643.1 - 0.0048 17.2 0.2 0.044 14.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EEQ37643.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 EEQ37643.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EEQ37643.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF87 PF01935.17 EEQ37643.1 - 0.036 14.2 0.1 0.087 12.9 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain DUF815 PF05673.13 EEQ37643.1 - 0.075 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FKBP_N_2 PF18023.1 EEQ37643.1 - 0.078 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 BDBT FKBP like N-terminal AAA_7 PF12775.7 EEQ37643.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EEQ37643.1 - 0.21 10.8 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AA_permease_2 PF13520.6 EEQ37644.1 - 5.6e-34 117.7 28.7 7.1e-34 117.4 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ37644.1 - 1.4e-05 23.9 25.1 1.9e-05 23.5 25.1 1.1 1 0 0 1 1 1 1 Amino acid permease Mito_carr PF00153.27 EEQ37646.1 - 6e-61 202.4 2.2 4.1e-21 74.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ37646.1 - 0.0016 17.6 0.2 0.3 10.2 0.0 2.4 2 0 0 2 2 2 2 Gammaproteobacterial serine protease Peptidase_M22 PF00814.25 EEQ37647.1 - 3.5e-56 190.9 0.0 9.5e-56 189.5 0.0 1.6 1 1 0 1 1 1 1 Glycoprotease family DUF3196 PF11428.8 EEQ37647.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) Nse4_C PF08743.10 EEQ37648.1 - 1.2e-29 102.4 0.1 3.1e-29 101.1 0.1 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EEQ37648.1 - 1.8e-06 28.0 0.0 3.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Mlh1_C PF16413.5 EEQ37649.1 - 2.3e-75 253.4 1.4 4.3e-75 252.6 1.4 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EEQ37649.1 - 1.6e-29 102.0 0.0 4.1e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EEQ37649.1 - 5.7e-12 45.6 0.1 1.4e-11 44.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EEQ37649.1 - 8.6e-06 26.2 0.2 2.6e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_14 PF13428.6 EEQ37650.1 - 0.0015 19.2 0.2 16 6.6 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ37650.1 - 0.0031 17.3 0.6 21 5.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ37650.1 - 0.0039 17.3 3.2 0.61 10.5 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat OSCP PF00213.18 EEQ37650.1 - 0.048 13.8 0.1 0.5 10.5 0.0 2.4 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit TPR_2 PF07719.17 EEQ37650.1 - 0.41 10.9 3.8 54 4.3 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ37650.1 - 0.46 10.7 7.1 20 5.5 0.0 4.7 5 1 1 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 SUI1 PF01253.22 EEQ37651.1 - 9.8e-22 77.3 1.6 1.9e-21 76.4 1.1 1.8 1 1 0 1 1 1 1 Translation initiation factor SUI1 Zn_clus PF00172.18 EEQ37653.1 - 1.8e-08 34.3 5.7 3e-08 33.7 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_16 PF13191.6 EEQ37654.1 - 7.3e-08 33.0 0.4 2.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EEQ37654.1 - 2.1e-07 31.1 0.0 2.1e-07 31.1 0.0 2.9 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EEQ37654.1 - 0.00054 20.2 0.0 0.0017 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EEQ37654.1 - 0.00074 19.5 0.0 0.033 14.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EEQ37654.1 - 0.0045 16.5 0.0 0.0095 15.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA PF00004.29 EEQ37654.1 - 0.013 15.9 0.1 0.039 14.4 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EEQ37654.1 - 0.014 14.7 0.4 0.025 13.8 0.0 1.5 2 0 0 2 2 1 0 TIP49 P-loop domain ATPase PF06745.13 EEQ37654.1 - 0.051 12.9 0.2 0.051 12.9 0.2 1.9 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 EEQ37654.1 - 0.056 12.5 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.15 EEQ37654.1 - 0.11 12.4 1.3 0.23 11.4 0.1 2.2 3 0 0 3 3 3 0 NTPase AAA_29 PF13555.6 EEQ37654.1 - 0.12 12.2 0.1 0.36 10.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EEQ37654.1 - 0.2 11.6 0.5 0.92 9.4 0.0 2.3 3 0 0 3 3 2 0 NACHT domain DUF4337 PF14235.6 EEQ37654.1 - 6.1 6.9 10.1 1.2 9.3 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) HECT PF00632.25 EEQ37655.1 - 2e-84 283.7 1.2 6.7e-84 282.0 0.1 2.2 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) HTH_AraC PF00165.23 EEQ37655.1 - 0.12 12.5 0.6 49 4.2 0.0 3.4 3 0 0 3 3 3 0 Bacterial regulatory helix-turn-helix proteins, AraC family Hydrolase_6 PF13344.6 EEQ37656.1 - 1.2e-28 99.2 0.0 2.3e-28 98.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ37656.1 - 1.8e-12 47.1 0.0 4.2e-12 46.0 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 EEQ37656.1 - 6.4e-08 32.9 0.1 0.00032 20.8 0.0 2.7 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ37656.1 - 3e-06 27.7 0.0 0.00017 22.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EEQ37656.1 - 0.027 14.1 0.0 0.041 13.5 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) STAS PF01740.21 EEQ37656.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 STAS domain Peptidase_M28 PF04389.17 EEQ37657.1 - 3.6e-23 82.3 0.0 9.7e-23 80.9 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.15 EEQ37657.1 - 3.9e-21 75.4 0.0 7.1e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.22 EEQ37657.1 - 6e-12 45.4 0.1 2.8e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EEQ37657.1 - 0.066 12.9 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Rpp20 PF12328.8 EEQ37659.1 - 8.9e-31 106.7 4.3 1.3e-30 106.1 4.3 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EEQ37659.1 - 3.3e-06 26.8 0.7 6e-06 26.0 0.7 1.5 1 0 0 1 1 1 1 Alba DUF3245 PF11595.8 EEQ37659.1 - 0.056 13.9 1.4 0.082 13.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Ribosomal_L24e PF01246.20 EEQ37660.1 - 6.1e-32 109.7 3.7 1.3e-31 108.6 3.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e Pam16 PF03656.13 EEQ37661.1 - 3.4e-07 30.3 0.0 4.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EEQ37661.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ANTH PF07651.16 EEQ37662.1 - 4.5e-61 206.3 2.3 4.5e-61 206.3 2.3 2.5 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 EEQ37662.1 - 6.7e-08 32.6 1.0 2.1e-07 31.0 0.3 2.3 2 0 0 2 2 2 1 ENTH domain Rhodanese PF00581.20 EEQ37663.1 - 8.6e-10 39.1 0.0 1.1e-09 38.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain CTP_transf_like PF01467.26 EEQ37664.1 - 2e-32 112.4 0.5 6.1e-32 110.8 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like Phage_int_SAM_5 PF13102.6 EEQ37664.1 - 0.11 12.9 4.5 2.1 8.8 1.6 3.0 2 1 1 3 3 3 0 Phage integrase SAM-like domain zf-CpG_bind_C PF12269.8 EEQ37664.1 - 0.44 10.3 3.7 3.1 7.5 0.1 2.4 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain MMM1 PF10296.9 EEQ37665.1 - 4.6e-141 469.7 0.0 5.8e-141 469.3 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Kdo PF06293.14 EEQ37666.1 - 2.9e-10 39.9 0.0 4.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ37666.1 - 1.2e-08 35.2 0.0 3e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ37666.1 - 2e-07 30.8 0.0 3.5e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EEQ37666.1 - 6e-07 29.1 0.0 6.9e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37666.1 - 4.9e-05 22.7 0.0 5.3e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 EEQ37666.1 - 5.7e-05 22.6 0.0 7.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase WaaY PF06176.11 EEQ37666.1 - 0.00042 20.0 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 EEQ37666.1 - 0.0027 17.3 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase CLTH PF10607.9 EEQ37667.1 - 6.7e-07 29.3 1.5 1.9e-06 27.8 0.2 2.2 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EEQ37667.1 - 0.0084 16.2 0.3 0.0084 16.2 0.3 2.8 3 1 0 3 3 3 1 SPRY domain 60KD_IMP PF02096.20 EEQ37669.1 - 7.6e-13 48.7 1.0 1.6e-12 47.7 0.2 1.7 2 0 0 2 2 2 1 60Kd inner membrane protein Spt4 PF06093.13 EEQ37670.1 - 2.3e-30 104.5 0.1 2.7e-30 104.3 0.1 1.0 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger WG_beta_rep PF14903.6 EEQ37670.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 WG containing repeat AAA PF00004.29 EEQ37671.1 - 2.7e-51 173.4 0.0 1.9e-42 144.8 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ37671.1 - 6.3e-10 38.7 0.0 2.1e-09 37.0 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EEQ37671.1 - 1.1e-05 25.6 0.0 7e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EEQ37671.1 - 1.4e-05 24.9 0.0 0.00033 20.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 EEQ37671.1 - 9.5e-05 22.8 0.0 9.5e-05 22.8 0.0 3.8 5 1 0 5 5 5 1 AAA ATPase domain Bromodomain PF00439.25 EEQ37671.1 - 0.00017 21.6 0.0 0.00053 20.0 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Sigma54_activ_2 PF14532.6 EEQ37671.1 - 0.00033 20.8 0.0 0.84 9.7 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 EEQ37671.1 - 0.00047 20.2 0.0 0.004 17.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ37671.1 - 0.0011 19.2 2.4 0.19 12.0 0.2 4.6 5 1 0 5 5 4 1 AAA domain AAA_18 PF13238.6 EEQ37671.1 - 0.0042 17.6 0.1 0.17 12.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EEQ37671.1 - 0.0085 15.8 0.0 1.9 8.2 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.6 EEQ37671.1 - 0.01 15.9 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EEQ37671.1 - 0.011 15.2 0.1 0.12 11.7 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EEQ37671.1 - 0.013 15.6 1.3 0.13 12.3 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EEQ37671.1 - 0.016 15.6 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.27 EEQ37671.1 - 0.029 14.9 0.0 0.27 11.8 0.0 2.6 2 0 0 2 2 2 0 ABC transporter TIP49 PF06068.13 EEQ37671.1 - 0.032 13.5 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_33 PF13671.6 EEQ37671.1 - 0.034 14.3 0.0 0.088 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EEQ37671.1 - 0.093 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EEQ37671.1 - 0.1 12.1 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 EEQ37671.1 - 0.55 10.0 0.0 0.55 10.0 0.0 3.0 3 1 0 3 3 2 0 AAA domain tRNA-synt_1g PF09334.11 EEQ37672.1 - 2.6e-96 322.8 0.2 4.3e-95 318.7 0.2 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EEQ37672.1 - 1.7e-20 72.8 0.7 2.3e-08 32.8 0.0 3.7 1 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EEQ37672.1 - 1.5e-12 47.5 0.1 1.5e-05 24.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EEQ37672.1 - 0.022 13.7 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Yip1 PF04893.17 EEQ37673.1 - 1.1e-08 35.0 14.4 1.7e-08 34.4 14.4 1.4 1 0 0 1 1 1 1 Yip1 domain SRP54 PF00448.22 EEQ37674.1 - 4.8e-48 163.4 1.5 1.2e-47 162.1 1.5 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EEQ37674.1 - 7e-07 28.5 0.0 1.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54_N PF02881.19 EEQ37674.1 - 4.4e-05 23.6 0.0 0.00018 21.6 0.0 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain SRP-alpha_N PF04086.13 EEQ37674.1 - 0.00019 21.4 3.2 0.00032 20.7 3.2 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal AAA_31 PF13614.6 EEQ37674.1 - 0.00051 20.0 0.4 0.02 14.8 0.1 2.7 2 1 1 3 3 3 1 AAA domain CbiA PF01656.23 EEQ37674.1 - 0.00084 19.4 0.0 0.0058 16.7 0.0 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 EEQ37674.1 - 0.00088 18.6 0.1 0.24 10.7 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin AAA_30 PF13604.6 EEQ37674.1 - 0.0014 18.4 0.8 0.0025 17.6 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEQ37674.1 - 0.0035 17.1 0.6 0.026 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ37674.1 - 0.0036 17.6 0.1 0.023 15.0 0.0 2.5 2 2 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EEQ37674.1 - 0.0046 16.2 0.1 0.14 11.3 0.0 2.5 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_17 PF13207.6 EEQ37674.1 - 0.0054 17.1 0.1 0.042 14.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EEQ37674.1 - 0.027 14.0 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ37674.1 - 0.04 14.3 0.0 0.42 11.0 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_14 PF13173.6 EEQ37674.1 - 0.074 13.1 0.1 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EEQ37674.1 - 0.21 11.7 2.5 5.4 7.1 2.3 2.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase GEN1_C PF18380.1 EEQ37674.1 - 2.5 9.0 9.2 0.13 13.1 2.1 2.2 1 1 1 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain PS_Dcarbxylase PF02666.15 EEQ37675.1 - 4.1e-56 189.7 0.0 6.4e-56 189.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EEQ37675.1 - 4.3e-29 100.8 0.2 3.4e-17 62.6 0.1 2.8 2 0 0 2 2 2 2 C2 domain Musclin PF11037.8 EEQ37675.1 - 0.05 13.5 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Peptidase_M23 PF01551.22 EEQ37675.1 - 0.13 12.5 0.3 0.72 10.1 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 SR-25 PF10500.9 EEQ37675.1 - 3.2 7.3 13.3 0.2 11.3 3.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein tRNA-synt_1g PF09334.11 EEQ37676.1 - 2.2e-155 517.3 2.4 2.7e-155 516.9 2.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EEQ37676.1 - 6.1e-09 34.7 0.9 0.00037 18.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) MetRS-N PF09635.10 EEQ37676.1 - 7.8e-05 23.2 1.2 0.00029 21.4 1.2 2.0 1 1 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1e PF01406.19 EEQ37676.1 - 0.02 14.2 0.2 0.17 11.2 0.1 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Amidase PF01425.21 EEQ37677.1 - 1.1e-96 324.6 2.1 1.4e-96 324.3 2.1 1.0 1 0 0 1 1 1 1 Amidase GTP_cyclohydroI PF01227.22 EEQ37678.1 - 2e-76 255.4 0.6 2.6e-76 255.1 0.6 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EEQ37678.1 - 6.3e-05 23.1 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein RNB PF00773.19 EEQ37679.1 - 2.6e-62 211.1 4.1 2.6e-62 211.1 4.1 1.7 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EEQ37679.1 - 5.4e-24 84.0 0.1 1.5e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EEQ37679.1 - 5.3e-22 78.0 1.4 9.5e-22 77.1 0.0 2.3 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 EEQ37679.1 - 6.2e-06 26.3 0.0 0.0027 17.9 0.0 2.9 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 EEQ37679.1 - 0.0035 17.1 1.1 0.014 15.2 0.5 2.3 2 1 0 2 2 2 1 Rrp44-like cold shock domain OB_RNB PF08206.11 EEQ37679.1 - 0.0052 16.4 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain NPR3 PF03666.13 EEQ37679.1 - 0.006 15.4 1.4 0.006 15.4 1.4 2.3 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 DNA_pol_E_B PF04042.16 EEQ37680.1 - 3.2e-40 137.7 0.0 6e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EEQ37680.1 - 3.5e-28 98.3 0.0 5.6e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Ten1 PF12658.7 EEQ37681.1 - 4.2e-22 78.4 0.0 4.8e-22 78.2 0.0 1.0 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Fungal_trans PF04082.18 EEQ37682.1 - 9e-24 83.9 0.0 4.5e-22 78.3 0.0 2.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ37682.1 - 4.6e-10 39.5 7.8 8.7e-10 38.6 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1373 PF07117.11 EEQ37685.1 - 0.031 14.3 1.1 0.92 9.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1373) SMC_Nse1 PF07574.13 EEQ37686.1 - 1.7e-17 64.0 0.0 1.7e-13 50.9 0.0 2.1 1 1 1 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EEQ37686.1 - 1.2e-08 35.1 7.3 1.9e-08 34.5 7.3 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 EEQ37686.1 - 0.001 19.3 4.5 0.0018 18.6 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-HC5HC2H_2 PF13832.6 EEQ37686.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain MarR_2 PF12802.7 EEQ37686.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 MarR family zf-HC5HC2H PF13771.6 EEQ37686.1 - 0.022 15.0 1.7 0.037 14.3 1.7 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain MarR PF01047.22 EEQ37686.1 - 0.027 14.4 0.0 0.05 13.5 0.0 1.4 1 0 0 1 1 1 0 MarR family zf-RING_5 PF14634.6 EEQ37686.1 - 0.084 12.8 5.8 0.14 12.2 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_9 PF13901.6 EEQ37686.1 - 0.097 12.6 1.0 0.39 10.7 1.0 2.0 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon TrmB PF01978.19 EEQ37686.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB zf-rbx1 PF12678.7 EEQ37686.1 - 0.22 11.8 4.8 0.54 10.6 4.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C2H2_12 PF18658.1 EEQ37686.1 - 0.5 10.0 1.7 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C3HC4_2 PF13923.6 EEQ37686.1 - 0.85 9.5 5.9 1.6 8.6 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EEQ37686.1 - 5.7 6.9 6.8 45 4.0 7.4 2.2 1 1 1 2 2 2 0 PHD-finger Glyco_hydro_16 PF00722.21 EEQ37687.1 - 6.7e-39 133.2 0.1 1.2e-38 132.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PFK PF00365.20 EEQ37688.1 - 3.3e-179 594.3 0.7 1.6e-99 332.9 0.4 2.3 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 EEQ37688.1 - 5e-29 100.6 0.0 1e-28 99.6 0.0 1.6 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast UVR PF02151.19 EEQ37688.1 - 0.0073 16.0 0.3 0.018 14.8 0.3 1.7 1 0 0 1 1 1 1 UvrB/uvrC motif DAGK_cat PF00781.24 EEQ37688.1 - 0.02 14.5 0.1 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Ribosomal_S11 PF00411.19 EEQ37688.1 - 0.054 13.9 0.1 0.16 12.4 0.1 1.8 1 0 0 1 1 1 0 Ribosomal protein S11 HSF_DNA-bind PF00447.17 EEQ37689.1 - 2.4e-26 92.2 0.1 3.5e-26 91.7 0.1 1.2 1 0 0 1 1 1 1 HSF-type DNA-binding NOP19 PF10863.8 EEQ37690.1 - 6.9e-18 64.8 12.0 4.7e-17 62.1 4.9 2.8 2 1 0 2 2 2 1 Nucleolar protein 19 DUF3245 PF11595.8 EEQ37690.1 - 0.046 14.2 11.5 0.63 10.5 11.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) DnaJ_CXXCXGXG PF00684.19 EEQ37692.1 - 1.4e-05 25.4 14.1 0.024 15.0 7.8 2.7 2 1 0 2 2 2 2 DnaJ central domain DUF35_N PF12172.8 EEQ37692.1 - 0.16 11.9 7.3 4.6 7.2 0.5 3.6 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TackOD1 PF18551.1 EEQ37692.1 - 0.2 11.3 6.8 1 9.0 0.2 2.8 3 0 0 3 3 3 0 Thaumarchaeal output domain 1 Prim_Zn_Ribbon PF08273.12 EEQ37692.1 - 2.5 8.5 9.4 4.2 7.7 0.3 3.9 4 0 0 4 4 4 0 Zinc-binding domain of primase-helicase HypA PF01155.19 EEQ37692.1 - 3 7.9 7.4 42 4.2 0.3 3.0 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Aldedh PF00171.22 EEQ37693.1 - 1.3e-106 356.9 0.0 1.6e-106 356.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dynamitin PF04912.14 EEQ37694.1 - 7.2e-34 117.8 18.5 3.4e-24 85.9 10.9 2.1 1 1 1 2 2 2 2 Dynamitin TPR_MLP1_2 PF07926.12 EEQ37694.1 - 0.00097 19.2 0.4 0.00097 19.2 0.4 3.7 2 1 0 3 3 3 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 EEQ37694.1 - 0.0025 17.9 5.8 0.059 13.4 0.8 3.1 2 1 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Cor1 PF04803.12 EEQ37694.1 - 0.0033 17.6 0.2 0.0033 17.6 0.2 2.8 3 1 1 4 4 3 1 Cor1/Xlr/Xmr conserved region Spc7 PF08317.11 EEQ37694.1 - 0.0062 15.5 0.4 0.0062 15.5 0.4 3.1 2 1 0 3 3 3 1 Spc7 kinetochore protein Gp58 PF07902.11 EEQ37694.1 - 0.01 14.2 2.5 0.011 14.1 0.4 1.8 1 1 1 2 2 2 0 gp58-like protein Sugarporin_N PF11471.8 EEQ37694.1 - 0.012 15.5 1.9 4.1 7.4 0.2 2.5 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Cep57_CLD_2 PF14197.6 EEQ37694.1 - 0.023 14.8 3.2 0.023 14.8 3.2 4.6 4 2 1 5 5 5 0 Centrosome localisation domain of PPC89 PspA_IM30 PF04012.12 EEQ37694.1 - 0.19 11.3 6.5 4.3 6.8 0.3 2.9 2 1 0 2 2 2 0 PspA/IM30 family DUF948 PF06103.11 EEQ37694.1 - 0.23 11.8 3.2 4.9 7.5 0.2 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 EEQ37694.1 - 0.32 11.1 16.7 1.2e+02 2.7 16.7 2.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prominin PF05478.11 EEQ37694.1 - 0.43 8.5 10.0 1.1 7.2 4.5 2.2 1 1 1 2 2 2 0 Prominin DUF1910 PF08928.10 EEQ37694.1 - 0.47 10.5 5.4 12 6.0 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1910) DUF4200 PF13863.6 EEQ37694.1 - 0.67 10.4 15.0 0.15 12.5 0.8 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.9 EEQ37694.1 - 1.1 9.6 13.5 11 6.4 0.4 5.0 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EEQ37694.1 - 1.7 9.2 9.3 39 4.8 0.3 4.6 3 1 2 5 5 5 0 Nucleopolyhedrovirus P10 protein TPD52 PF04201.15 EEQ37694.1 - 1.9 8.1 9.3 3.6 7.2 0.7 2.9 2 1 1 3 3 3 0 Tumour protein D52 family HSCB_C PF07743.13 EEQ37694.1 - 2.8 8.5 11.4 6.4 7.3 0.7 3.7 3 1 1 4 4 4 0 HSCB C-terminal oligomerisation domain Filament PF00038.21 EEQ37694.1 - 3 7.3 15.6 1.3 8.5 0.9 2.7 1 1 1 2 2 2 0 Intermediate filament protein GTP-bdg_M PF16360.5 EEQ37694.1 - 3.8 8.2 5.1 54 4.5 0.1 3.7 3 0 0 3 3 3 0 GTP-binding GTPase Middle Region DUF5082 PF16888.5 EEQ37694.1 - 3.9 7.8 13.3 10 6.4 0.2 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 EEQ37694.1 - 4.3 7.5 14.4 1.9 8.7 1.0 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DHR10 PF18595.1 EEQ37694.1 - 4.3 7.4 13.4 1.4 9.0 0.3 3.6 2 1 0 3 3 3 0 Designed helical repeat protein 10 domain YlqD PF11068.8 EEQ37694.1 - 4.6 7.6 7.7 5.2 7.5 0.2 3.1 2 1 1 3 3 3 0 YlqD protein Seryl_tRNA_N PF02403.22 EEQ37694.1 - 5 7.4 13.3 1.2 9.4 0.8 3.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FlaC_arch PF05377.11 EEQ37694.1 - 6.2 7.3 14.3 19 5.8 0.8 5.1 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) KxDL PF10241.9 EEQ37694.1 - 8.3 6.8 14.4 4.3 7.7 2.5 4.2 3 2 1 4 4 4 0 Uncharacterized conserved protein MMR_HSR1_Xtn PF16897.5 EEQ37695.1 - 6e-37 125.9 1.9 6.4e-37 125.8 0.8 1.7 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EEQ37695.1 - 2.1e-20 72.9 0.2 4.7e-20 71.8 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EEQ37695.1 - 9.1e-19 67.3 0.0 2e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EEQ37695.1 - 2.2e-13 50.0 0.1 3.9e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEQ37695.1 - 0.0048 17.0 1.2 0.13 12.3 0.0 2.5 1 1 1 2 2 2 1 Dynamin family Roc PF08477.13 EEQ37695.1 - 0.041 14.1 0.2 1 9.6 0.1 2.4 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MCM PF00493.23 EEQ37695.1 - 0.078 12.1 0.1 0.33 10.0 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain NAT PF04768.13 EEQ37695.1 - 0.14 11.9 0.0 0.27 10.9 0.0 1.7 1 1 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase Efg1 PF10153.9 EEQ37696.1 - 3e-31 108.2 13.8 3e-31 108.2 13.8 1.9 2 1 0 2 2 2 1 rRNA-processing protein Efg1 YfdX PF10938.8 EEQ37696.1 - 0.07 13.1 5.7 0.37 10.7 3.9 2.4 1 1 1 2 2 2 0 YfdX protein PWWP PF00855.17 EEQ37696.1 - 1 9.8 5.4 6.3 7.3 2.2 2.3 1 1 1 2 2 2 0 PWWP domain Sec63 PF02889.16 EEQ37697.1 - 5e-122 406.0 2.4 1.6e-76 256.9 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EEQ37697.1 - 5.8e-51 172.7 1.6 1.8e-25 89.8 0.7 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 EEQ37697.1 - 2.8e-28 99.1 0.0 1.5e-14 54.3 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ37697.1 - 1.3e-18 67.3 0.0 1.1e-07 32.2 0.0 4.3 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EEQ37697.1 - 1.3e-07 32.0 0.4 0.041 14.2 0.3 3.5 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EEQ37697.1 - 0.00017 21.9 0.5 0.054 13.8 0.7 2.9 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 EEQ37697.1 - 0.00048 20.3 0.8 0.0016 18.6 0.8 1.9 1 0 0 1 1 1 1 N-terminal helicase PWI domain AAA PF00004.29 EEQ37697.1 - 0.00062 20.2 5.0 0.14 12.6 0.0 4.1 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EEQ37697.1 - 0.0036 16.8 0.0 0.31 10.5 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 EEQ37697.1 - 0.01 15.6 0.0 7.3 6.3 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein Alba PF01918.21 EEQ37697.1 - 0.15 11.9 0.0 0.55 10.1 0.0 2.0 1 0 0 1 1 1 0 Alba TniB PF05621.11 EEQ37697.1 - 0.27 10.6 2.8 18 4.7 0.1 3.9 4 0 0 4 4 4 0 Bacterial TniB protein DEAD PF00270.29 EEQ37698.1 - 1.6e-46 158.3 0.7 3e-46 157.4 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ37698.1 - 8.3e-24 84.1 0.0 3.8e-23 82.0 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEQ37698.1 - 6.9e-17 61.4 0.2 1.4e-16 60.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 EEQ37698.1 - 0.062 13.6 0.9 0.31 11.3 0.1 2.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 EEQ37698.1 - 0.11 12.3 0.1 6.5 6.7 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B F-protein PF00469.20 EEQ37698.1 - 3.2 7.3 5.7 5.6 6.5 5.7 1.4 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef RNA_pol_Rpb4 PF03874.16 EEQ37699.1 - 2e-29 102.4 0.1 3.3e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb4 ING PF12998.7 EEQ37699.1 - 0.12 12.9 0.9 0.86 10.2 0.2 2.3 1 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF676 PF05057.14 EEQ37700.1 - 2.3e-52 177.7 0.1 3.9e-52 176.9 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EEQ37700.1 - 0.0025 17.7 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Dynamin_M PF01031.20 EEQ37700.1 - 0.051 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Dynamin central region PGAP1 PF07819.13 EEQ37700.1 - 0.087 12.5 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein OST3_OST6 PF04756.13 EEQ37701.1 - 3.5e-88 295.8 0.9 4.3e-88 295.5 0.9 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EEQ37701.1 - 0.0097 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Peptidase_C2 PF00648.21 EEQ37702.1 - 2.9e-06 26.5 0.0 3.6e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Calpain family cysteine protease Calpain_III PF01067.22 EEQ37702.1 - 2.8e-05 24.4 0.9 0.11 12.7 0.0 3.5 3 1 0 3 3 3 2 Calpain large subunit, domain III DUF4195 PF13836.6 EEQ37702.1 - 2.4 8.3 8.4 19 5.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4195) Glyco_transf_22 PF03901.17 EEQ37703.1 - 1.2e-84 285.0 23.6 1.4e-84 284.8 23.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ADH_N PF08240.12 EEQ37704.1 - 3e-29 101.1 3.1 3e-29 101.1 1.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ37704.1 - 6.3e-27 94.1 1.1 1.1e-26 93.3 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ37704.1 - 0.00054 21.0 0.0 0.00097 20.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEQ37704.1 - 0.016 14.5 0.5 0.031 13.6 0.3 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 EEQ37704.1 - 0.036 13.8 0.4 0.051 13.3 0.4 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ACP_syn_III_C PF08541.10 EEQ37704.1 - 0.15 12.2 0.6 0.64 10.2 0.2 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ATG16 PF08614.11 EEQ37705.1 - 3.5e-13 50.2 28.4 2.6e-12 47.4 27.9 2.3 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EEQ37705.1 - 0.085 13.4 21.0 27 5.3 21.0 2.2 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 EEQ37705.1 - 0.12 12.1 19.8 0.32 10.8 3.4 3.5 1 1 2 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 EEQ37705.1 - 0.16 12.1 16.5 2.7 8.1 1.6 3.6 2 1 0 3 3 3 0 Basic region leucine zipper SYCE1 PF15233.6 EEQ37705.1 - 0.61 10.1 21.8 3.5 7.7 2.7 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 PikAIV_N PF18605.1 EEQ37705.1 - 0.94 9.1 8.8 0.29 10.7 0.9 2.9 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Mod_r PF07200.13 EEQ37705.1 - 1 9.5 18.5 17 5.5 18.5 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.18 EEQ37705.1 - 1.4 9.2 13.5 2 8.7 0.4 3.5 3 1 0 3 3 3 0 Homeobox associated leucine zipper TMPIT PF07851.13 EEQ37705.1 - 2.2 7.4 10.2 3.2 6.9 10.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Cep57_CLD_2 PF14197.6 EEQ37705.1 - 2.3 8.3 21.3 3.8 7.7 5.1 3.4 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 YabA PF06156.13 EEQ37705.1 - 2.5 8.8 17.0 0.73 10.5 4.5 2.5 1 1 1 2 2 2 0 Initiation control protein YabA Med30 PF11315.8 EEQ37705.1 - 2.8 8.1 14.5 3.6 7.8 6.8 2.2 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF3450 PF11932.8 EEQ37705.1 - 4.3 6.6 16.6 5.7 6.2 3.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 EEQ37705.1 - 5.3 6.0 16.8 9.5 5.2 16.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 RBD-FIP PF09457.10 EEQ37705.1 - 9 6.3 8.1 1.5 8.8 0.3 3.0 3 0 0 3 3 3 0 FIP domain Homeodomain PF00046.29 EEQ37707.1 - 8.3e-18 64.0 0.6 1.6e-17 63.0 0.6 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EEQ37707.1 - 2.2e-05 24.3 0.3 5.4e-05 23.0 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Sel1 PF08238.12 EEQ37708.1 - 0.002 18.7 1.5 8.8 7.2 0.0 4.8 4 1 0 4 4 4 2 Sel1 repeat Pkinase PF00069.25 EEQ37709.1 - 1.7e-68 230.9 0.0 2.2e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37709.1 - 1.5e-32 112.9 0.0 2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EEQ37709.1 - 3.1e-16 59.5 0.1 6.7e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 FHA domain Pkinase_fungal PF17667.1 EEQ37709.1 - 6.8e-05 21.8 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EEQ37709.1 - 8.6e-05 22.8 0.0 0.00018 21.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EEQ37709.1 - 0.0053 16.1 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA_2 PF17913.1 EEQ37709.1 - 0.02 15.1 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 FHA domain Kinase-like PF14531.6 EEQ37709.1 - 0.021 14.1 0.0 8.5 5.6 0.0 3.0 3 0 0 3 3 3 0 Kinase-like YrhC PF14143.6 EEQ37710.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.6 4 0 0 4 4 4 0 YrhC-like protein Glyco_trans_2_3 PF13632.6 EEQ37711.1 - 1.3e-27 97.0 1.7 1.3e-27 97.0 1.7 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EEQ37711.1 - 0.015 15.1 0.0 0.048 13.5 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EEQ37711.1 - 0.033 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2207 PF09972.9 EEQ37711.1 - 0.037 12.8 0.8 0.056 12.2 0.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_16 PF00722.21 EEQ37712.1 - 4.4e-18 65.4 0.3 8.3e-18 64.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PetL PF05115.14 EEQ37712.1 - 0.2 11.7 2.8 0.42 10.6 2.8 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) RINT1_TIP1 PF04437.13 EEQ37713.1 - 8.5e-107 358.1 13.0 1.2e-106 357.6 13.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Cpn60_TCP1 PF00118.24 EEQ37714.1 - 1.9e-167 557.8 3.9 2.2e-167 557.6 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NusA_N PF08529.11 EEQ37714.1 - 0.054 13.8 1.3 0.25 11.7 1.3 2.1 1 0 0 1 1 1 0 NusA N-terminal domain SH3_1 PF00018.28 EEQ37715.1 - 9e-07 28.4 0.3 1.8e-06 27.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ37715.1 - 9.4e-05 22.0 0.1 0.00018 21.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EEQ37715.1 - 0.00074 19.3 0.4 0.002 17.9 0.4 1.7 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core PF01841.19 EEQ37715.1 - 0.0033 17.9 0.0 0.0088 16.5 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily BBS2_C PF14782.6 EEQ37715.1 - 0.017 13.9 0.4 0.028 13.2 0.4 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, C-terminal Pkinase PF00069.25 EEQ37718.1 - 2.9e-67 226.8 0.0 3.2e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37718.1 - 2.5e-28 99.1 0.0 2.7e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ37718.1 - 0.00089 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ37718.1 - 0.01 15.8 0.9 0.016 15.1 0.2 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EEQ37718.1 - 0.093 12.1 0.3 0.34 10.2 0.3 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DAO PF01266.24 EEQ37719.1 - 3.1e-61 207.9 0.4 3.5e-61 207.8 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ37719.1 - 4.9e-07 29.9 0.2 1.8e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EEQ37719.1 - 2.2e-06 27.0 1.9 9.8e-06 24.9 1.9 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EEQ37719.1 - 5.7e-06 25.8 0.0 0.00047 19.5 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ37719.1 - 0.0002 20.5 0.3 0.11 11.5 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.7 EEQ37719.1 - 0.00024 20.6 0.3 0.0022 17.4 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEQ37719.1 - 0.00031 21.2 0.1 0.00074 20.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EEQ37719.1 - 0.00031 20.1 0.3 0.63 9.2 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EEQ37719.1 - 0.0032 16.2 0.2 0.0054 15.5 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.6 EEQ37719.1 - 0.004 17.6 0.0 0.0084 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 EEQ37719.1 - 0.0074 15.6 0.5 0.026 13.8 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EEQ37719.1 - 0.0097 15.2 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EEQ37719.1 - 0.012 14.7 0.2 0.017 14.2 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.18 EEQ37719.1 - 0.019 15.2 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 EEQ37719.1 - 0.12 12.1 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA VTC PF09359.10 EEQ37720.1 - 7.1e-102 340.5 0.0 7.1e-102 340.5 0.0 2.0 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EEQ37720.1 - 4.8e-12 46.1 3.3 4.8e-12 46.1 3.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EEQ37720.1 - 3.7e-07 30.4 25.1 7.3e-06 26.1 2.2 3.7 2 1 2 4 4 4 3 SPX domain MazG PF03819.17 EEQ37720.1 - 0.0055 16.9 0.2 0.014 15.6 0.2 1.6 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain MtrE PF04206.12 EEQ37720.1 - 0.067 12.5 0.5 0.091 12.1 0.5 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E DegS PF05384.11 EEQ37720.1 - 0.099 12.1 4.1 0.039 13.4 0.6 2.0 2 0 0 2 2 2 0 Sensor protein DegS TACC_C PF05010.14 EEQ37720.1 - 0.7 9.6 6.8 0.33 10.7 3.4 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal YscO-like PF16789.5 EEQ37720.1 - 8.4 6.4 11.0 1.5 8.8 1.8 2.5 2 1 0 2 2 2 0 YscO-like protein PhoLip_ATPase_C PF16212.5 EEQ37721.1 - 3.1e-65 220.4 23.8 3.1e-65 220.4 23.8 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEQ37721.1 - 4e-24 84.1 5.6 1.3e-22 79.3 0.2 3.5 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EEQ37721.1 - 4.4e-15 56.5 1.0 6.5e-07 29.8 0.1 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ37721.1 - 4.7e-11 42.5 0.0 1.5e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EEQ37721.1 - 3.1e-10 40.0 0.1 1.8e-09 37.6 0.0 2.3 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EEQ37721.1 - 0.0019 18.0 2.1 0.0087 15.8 0.0 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ37721.1 - 0.01 15.9 2.2 0.027 14.6 0.4 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase GA-like PF17573.2 EEQ37721.1 - 1.1 9.2 3.5 32 4.6 0.1 3.5 3 0 0 3 3 3 0 GA-like domain Pyr_redox_2 PF07992.14 EEQ37722.1 - 3.1e-28 98.8 0.0 4.7e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ37722.1 - 2.6e-08 34.3 0.2 1.3e-06 28.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ37722.1 - 3.3e-06 27.2 0.4 0.24 11.4 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EEQ37722.1 - 0.00036 19.9 0.0 0.0007 18.9 0.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ37722.1 - 0.036 13.2 0.0 0.14 11.3 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EEQ37722.1 - 0.12 11.4 0.0 12 4.8 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.19 EEQ37722.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.24 EEQ37722.1 - 1.2 8.6 0.0 1.2 8.6 0.0 2.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase DUF3446 PF11928.8 EEQ37723.1 - 6.5 7.1 11.9 2 8.8 3.6 2.3 2 0 0 2 2 2 0 Early growth response N-terminal domain Mad3_BUB1_I PF08311.12 EEQ37724.1 - 4.7e-43 146.1 0.1 7.8e-43 145.4 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EEQ37724.1 - 1.7e-12 47.3 0.1 3.3e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 EEQ37724.1 - 4.6e-07 30.0 0.0 7.9e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein TPR_14 PF13428.6 EEQ37724.1 - 0.027 15.3 0.8 0.37 11.7 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RGS-like PF09128.11 EEQ37724.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Gpi16 PF04113.14 EEQ37725.1 - 3.3e-187 623.4 0.0 4e-187 623.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component MPM1 PF17234.2 EEQ37726.1 - 0.0014 18.9 4.1 0.034 14.4 0.8 2.3 1 1 1 2 2 2 2 Mitochondrial peculiar membrane protein 1 Elong_Iki1 PF10483.9 EEQ37727.1 - 3.9e-72 243.3 0.8 4.5e-72 243.1 0.8 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 HEAT_2 PF13646.6 EEQ37728.1 - 9.2e-11 42.0 34.0 0.0053 17.1 0.6 8.8 5 2 3 8 8 8 4 HEAT repeats HEAT PF02985.22 EEQ37728.1 - 1.4e-09 37.4 23.2 0.01 16.0 0.0 9.7 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 EEQ37728.1 - 4.6e-05 23.8 45.2 0.11 13.0 0.5 9.9 10 1 0 10 10 10 4 HEAT-like repeat MMS19_C PF12460.8 EEQ37728.1 - 0.00034 19.9 0.5 0.008 15.3 0.0 3.1 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Dopey_N PF04118.14 EEQ37728.1 - 0.00057 19.1 0.0 3.6 6.6 0.0 3.4 3 0 0 3 3 3 1 Dopey, N-terminal NUC173 PF08161.12 EEQ37728.1 - 0.00065 19.4 0.9 11 5.6 0.0 4.8 5 1 0 5 5 5 1 NUC173 domain Cnd1 PF12717.7 EEQ37728.1 - 0.0021 18.1 4.7 6.6 6.8 0.0 5.5 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 EEQ37728.1 - 0.0024 17.0 0.0 9.2 5.3 0.0 4.2 2 1 0 3 3 3 1 Interferon-related developmental regulator (IFRD) DRIM PF07539.12 EEQ37728.1 - 0.0046 15.3 0.1 0.13 10.5 0.0 2.9 1 1 1 3 3 3 1 Down-regulated in metastasis Arm PF00514.23 EEQ37728.1 - 0.0048 16.9 5.3 0.21 11.7 0.1 5.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EEQ37728.1 - 0.0052 15.4 0.6 0.67 8.4 0.0 3.1 2 2 0 2 2 2 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EEQ37728.1 - 0.015 15.9 0.0 12 6.6 0.0 5.0 5 1 1 6 6 6 0 Vacuolar 14 Fab1-binding region TPR_20 PF14561.6 EEQ37728.1 - 0.019 15.3 0.2 4.2 7.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 EEQ37728.1 - 1.9 9.4 8.9 19 6.3 0.3 5.3 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat TetR_C_34 PF17929.1 EEQ37728.1 - 2.6 8.2 10.0 1.4 9.0 0.6 4.7 5 1 0 5 5 5 0 Tetracyclin repressor-like, C-terminal domain XPG_N PF00752.17 EEQ37729.1 - 1.6e-33 115.2 0.0 4.1e-33 113.9 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EEQ37729.1 - 1.6e-27 95.7 0.1 1.6e-27 95.7 0.1 2.6 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 EEQ37729.1 - 0.0027 18.3 0.0 0.0027 18.3 0.0 3.0 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold SATase_N PF06426.14 EEQ37729.1 - 0.019 15.3 0.8 0.066 13.6 0.8 1.9 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal Transposase_20 PF02371.16 EEQ37729.1 - 0.031 14.6 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family NUC153 PF08159.12 EEQ37729.1 - 0.047 13.5 3.2 3.5 7.5 0.0 3.3 3 0 0 3 3 3 0 NUC153 domain HHH_5 PF14520.6 EEQ37729.1 - 0.048 14.3 0.0 0.42 11.2 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain IZUMO PF15005.6 EEQ37729.1 - 0.59 10.6 9.9 0.72 10.4 0.8 3.1 3 0 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated Synaptobrevin PF00957.21 EEQ37729.1 - 3.7 7.4 5.7 1.4 8.8 0.1 2.7 2 0 0 2 2 2 0 Synaptobrevin Adaptin_N PF01602.20 EEQ37730.1 - 3.6e-64 217.2 0.0 4.6e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEQ37730.1 - 1.3e-11 44.8 0.0 6.5e-10 39.3 0.0 3.1 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ37730.1 - 7.4e-09 35.9 26.3 4.5e-06 27.0 6.6 5.4 3 2 2 5 5 5 2 HEAT repeats HEAT PF02985.22 EEQ37730.1 - 8.5e-07 28.7 8.0 0.53 10.7 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat NESP55 PF06390.12 EEQ37730.1 - 2.9e-05 23.8 16.3 6.4e-05 22.7 16.3 1.6 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 EEQ37730.1 - 0.015 15.3 13.5 0.04 13.9 13.5 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DARPP-32 PF05395.12 EEQ37730.1 - 0.051 13.8 16.0 0.11 12.8 16.0 1.5 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Cohesin_HEAT PF12765.7 EEQ37730.1 - 0.73 10.2 6.5 17 5.8 0.1 4.2 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion SDA1 PF05285.12 EEQ37730.1 - 7.4 5.9 25.2 11 5.3 25.2 1.2 1 0 0 1 1 1 0 SDA1 HEAT_EZ PF13513.6 EEQ37730.1 - 7.8 7.1 20.5 8.8 7.0 0.1 6.1 5 2 2 7 7 7 0 HEAT-like repeat AF-4 PF05110.13 EEQ37730.1 - 8.6 4.3 31.9 14 3.6 31.9 1.3 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Flo11 PF10182.9 EEQ37731.1 - 1.1e-08 35.4 0.0 1.7e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Flo11 domain DUF4529 PF15032.6 EEQ37731.1 - 0.14 11.2 2.0 0.23 10.6 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) zf_C2H2_13 PF18508.1 EEQ37732.1 - 0.15 11.6 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Zinc finger domain AdoHcyase PF05221.17 EEQ37733.1 - 1.8e-127 424.6 0.0 1.8e-74 250.6 0.0 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EEQ37733.1 - 5.3e-83 276.9 3.1 8.4e-83 276.3 3.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EEQ37733.1 - 7.2e-08 32.0 0.1 1.6e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EEQ37733.1 - 0.046 13.4 0.1 0.079 12.7 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.12 EEQ37733.1 - 0.046 13.3 0.1 0.098 12.2 0.1 1.5 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Zn_clus PF00172.18 EEQ37734.1 - 5.7e-06 26.3 7.8 1.2e-05 25.4 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ37734.1 - 2.1e-05 23.7 0.0 4.7e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain GATA PF00320.27 EEQ37735.1 - 1.5e-14 53.3 4.4 2.9e-14 52.4 4.4 1.5 1 0 0 1 1 1 1 GATA zinc finger IF4E PF01652.18 EEQ37736.1 - 7.3e-27 94.1 0.3 2.1e-26 92.6 0.2 1.8 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E DUF4834 PF16118.5 EEQ37736.1 - 3.7 8.6 10.8 10 7.1 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Peptidase_M20 PF01546.28 EEQ37738.1 - 9.2e-30 103.9 0.1 1.5e-29 103.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ37738.1 - 3.8e-13 49.3 0.0 6.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ37738.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 DUF4550 PF15084.6 EEQ37738.1 - 0.18 12.2 0.1 0.37 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) DUF1515 PF07439.11 EEQ37739.1 - 0.072 13.1 1.9 1.7 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) HAD_2 PF13419.6 EEQ37740.1 - 5.2e-07 29.9 0.1 8.9e-07 29.2 0.1 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ37740.1 - 0.028 14.7 0.0 0.63 10.3 0.0 2.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase FSH1 PF03959.13 EEQ37741.1 - 1.2e-58 198.3 0.0 1.7e-58 197.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EEQ37741.1 - 0.012 16.2 0.0 0.018 15.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ37741.1 - 0.06 13.0 0.1 0.99 9.0 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold Thioredoxin PF00085.20 EEQ37742.1 - 9.4e-22 77.0 0.1 1.3e-20 73.3 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 EEQ37742.1 - 5.8e-08 32.4 0.0 2.7e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EEQ37742.1 - 1.1e-07 32.2 0.0 2.7e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EEQ37742.1 - 0.0017 18.6 0.0 0.086 13.2 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EEQ37742.1 - 0.0023 18.0 0.2 0.0092 16.1 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EEQ37742.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein ERp29_N PF07912.13 EEQ37742.1 - 0.063 13.4 0.0 3.2 7.9 0.0 2.4 2 1 0 2 2 2 0 ERp29, N-terminal domain Thioredoxin_6 PF13848.6 EEQ37742.1 - 0.21 11.5 1.0 15 5.4 0.1 3.2 2 1 1 3 3 3 0 Thioredoxin-like domain Scramblase PF03803.15 EEQ37743.1 - 1.4e-60 204.4 0.0 1.8e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Scramblase Mito_carr PF00153.27 EEQ37744.1 - 2.2e-68 226.2 0.9 3.4e-23 81.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 EEQ37744.1 - 0.13 12.4 1.9 0.99 9.5 0.1 2.9 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Amido_AtzD_TrzD PF09663.10 EEQ37744.1 - 0.16 11.0 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase ring-opening protein (Amido_AtzD_TrzD) Ytp1 PF10355.9 EEQ37745.1 - 1.4e-60 204.9 21.4 2.8e-59 200.6 21.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Peptidase_S8 PF00082.22 EEQ37746.1 - 8.2e-40 136.9 2.9 8.2e-40 136.9 2.9 1.8 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.20 EEQ37746.1 - 4.5e-20 71.5 0.1 1.1e-19 70.3 0.1 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain G6PD_C PF02781.16 EEQ37747.1 - 4.7e-108 360.8 0.0 6.3e-108 360.4 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EEQ37747.1 - 2.9e-60 203.9 0.0 8.2e-60 202.4 0.0 1.8 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Peptidase_S8 PF00082.22 EEQ37748.1 - 2.3e-27 96.1 6.7 9.7e-27 94.0 6.6 1.8 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ37748.1 - 1.7e-12 47.8 0.1 3.1e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sec23_trunk PF04811.15 EEQ37749.1 - 4.7e-64 216.3 0.0 6.5e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EEQ37749.1 - 4.9e-23 80.9 0.0 1.9e-22 79.0 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EEQ37749.1 - 2.8e-18 66.4 0.0 6.7e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EEQ37749.1 - 1.8e-16 59.8 2.0 3.9e-16 58.8 2.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EEQ37749.1 - 0.0031 17.4 0.0 0.01 15.7 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EEQ37749.1 - 0.21 11.0 0.1 0.76 9.2 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain COG5 PF10392.9 EEQ37751.1 - 3.2e-29 101.8 0.0 6e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Golgi transport complex subunit 5 EcKinase PF02958.20 EEQ37751.1 - 0.13 11.5 1.9 2.2 7.5 0.2 2.3 1 1 1 2 2 2 0 Ecdysteroid kinase DUF2011 PF09428.10 EEQ37752.1 - 3e-11 43.4 0.2 6.7e-11 42.3 0.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) CDC45 PF02724.14 EEQ37752.1 - 0.81 7.9 6.5 0.87 7.8 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF5542 PF17696.1 EEQ37752.1 - 0.85 9.8 2.7 1.5 9.0 2.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Ank_2 PF12796.7 EEQ37753.1 - 4e-31 107.4 0.4 8.2e-12 45.6 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ37753.1 - 1.2e-23 83.2 0.3 2.4e-09 37.6 0.0 4.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ37753.1 - 2.2e-23 79.8 0.1 3.2e-07 30.1 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EEQ37753.1 - 4e-23 81.2 1.3 2.3e-07 31.0 0.2 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EEQ37753.1 - 1.9e-19 69.1 3.2 1.4e-06 28.5 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat DSPc PF00782.20 EEQ37755.1 - 1.5e-32 112.2 0.0 3.5e-32 111.0 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEQ37755.1 - 0.0015 18.2 0.0 0.002 17.7 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EEQ37755.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EEQ37755.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Fer4 PF00037.27 EEQ37756.1 - 7.4e-14 50.9 17.0 3.5e-08 32.9 4.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EEQ37756.1 - 6e-13 49.2 9.6 1.4e-12 48.0 9.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EEQ37756.1 - 1.1e-10 42.3 11.0 1.9e-05 25.5 1.4 2.6 2 1 1 3 3 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EEQ37756.1 - 2e-10 40.6 21.3 2.9e-07 30.5 11.9 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EEQ37756.1 - 1e-09 38.4 20.8 3.9e-08 33.3 10.2 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EEQ37756.1 - 6.1e-09 35.9 32.4 8.1e-06 25.9 12.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_8 PF13183.6 EEQ37756.1 - 1.1e-08 35.4 5.6 6e-05 23.4 0.8 2.5 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EEQ37756.1 - 1.4e-06 28.1 17.5 0.00038 20.4 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EEQ37756.1 - 1.8e-06 27.7 11.3 0.0054 16.8 1.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EEQ37756.1 - 2.5e-05 24.4 12.1 0.00048 20.4 2.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EEQ37756.1 - 8.8e-05 23.0 12.2 0.017 15.7 2.1 2.4 1 1 0 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 EEQ37756.1 - 0.03 14.9 15.0 0.71 10.5 4.3 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I c-SKI_SMAD_bind PF08782.10 EEQ37756.1 - 0.042 14.1 6.8 0.51 10.6 0.3 2.4 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.7 EEQ37756.1 - 0.049 14.6 15.7 0.11 13.5 3.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EEQ37756.1 - 0.075 13.2 9.6 0.84 9.9 1.3 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EEQ37756.1 - 0.21 12.4 11.4 0.63 10.9 1.2 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 EEQ37756.1 - 0.27 11.4 6.2 0.68 10.1 0.6 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S GTP_cyclohydro2 PF00925.20 EEQ37757.1 - 1.3e-59 200.5 0.0 1.7e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF885 PF05960.11 EEQ37758.1 - 0.0052 16.5 0.3 0.0058 16.3 0.3 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) RPA_C PF08784.11 EEQ37758.1 - 0.091 13.4 0.2 0.54 10.9 0.1 2.0 2 0 0 2 2 2 0 Replication protein A C terminal EMP24_GP25L PF01105.24 EEQ37758.1 - 3.1 7.7 8.9 14 5.6 5.1 2.8 1 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Rgp1 PF08737.10 EEQ37759.1 - 3.8e-20 72.5 0.0 2.8e-19 69.6 0.0 2.0 1 1 0 1 1 1 1 Rgp1 Pkinase PF00069.25 EEQ37760.1 - 6.9e-69 232.1 0.0 9.1e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37760.1 - 1.9e-31 109.3 0.0 2.9e-31 108.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ37760.1 - 9.2e-06 24.8 0.1 1.3e-05 24.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEQ37760.1 - 0.00018 20.9 0.1 0.00088 18.7 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ37760.1 - 0.00067 19.1 0.0 0.0085 15.4 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 EEQ37760.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EEQ37760.1 - 0.023 14.3 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EEQ37760.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family ANAPC4_WD40 PF12894.7 EEQ37762.1 - 3.7e-18 65.6 0.9 4.1e-06 27.0 0.1 4.3 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ37762.1 - 2.6e-15 56.6 12.5 0.00019 22.2 0.4 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EEQ37762.1 - 3.8e-07 29.4 0.0 0.00022 20.3 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Snf7 PF03357.21 EEQ37763.1 - 3.5e-31 108.1 2.2 4.3e-31 107.8 2.2 1.1 1 0 0 1 1 1 1 Snf7 YfdX PF10938.8 EEQ37763.1 - 0.02 14.8 0.1 0.05 13.5 0.1 1.8 1 1 0 1 1 1 0 YfdX protein RTP PF02334.16 EEQ37763.1 - 0.073 13.7 0.5 0.17 12.5 0.2 1.7 2 0 0 2 2 2 0 Replication terminator protein BRE1 PF08647.11 EEQ37763.1 - 1.2 9.2 7.1 0.24 11.5 1.9 2.5 2 2 0 2 2 2 0 BRE1 E3 ubiquitin ligase ALAD PF00490.21 EEQ37764.1 - 1.1e-114 382.9 0.0 1.4e-114 382.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PQ-loop PF04193.14 EEQ37765.1 - 4e-09 36.1 2.3 0.00018 21.2 0.4 3.2 3 0 0 3 3 3 2 PQ loop repeat Nsp1_C PF05064.13 EEQ37766.1 - 2.2e-36 124.2 8.4 2.2e-36 124.2 8.4 2.4 2 0 0 2 2 2 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EEQ37766.1 - 3e-15 56.8 177.9 0.0026 18.6 18.4 8.2 1 1 5 6 6 6 3 Nucleoporin FG repeat region Nucleoporin_FG2 PF15967.5 EEQ37766.1 - 0.0001 21.0 1.7 0.0001 21.0 1.7 7.1 1 1 7 8 8 8 5 Nucleoporin FG repeated region APG6_N PF17675.1 EEQ37766.1 - 0.014 15.9 11.9 0.015 15.9 3.8 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region GvpK PF05121.12 EEQ37766.1 - 0.87 9.7 3.5 18 5.5 2.1 2.5 2 0 0 2 2 2 0 Gas vesicle protein K Phage_lysis PF03245.13 EEQ37766.1 - 0.99 9.5 5.0 5.8 7.1 5.0 2.3 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein Phage_GP20 PF06810.11 EEQ37766.1 - 1.4 8.7 13.1 0.43 10.4 5.9 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 EEQ37766.1 - 2.6 8.6 12.9 6.8 7.2 0.2 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 EEQ37766.1 - 2.7 7.5 6.3 7.2 6.1 6.3 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit His_Phos_1 PF00300.22 EEQ37767.1 - 1e-35 123.2 0.0 3.2e-29 102.0 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF4047 PF13256.6 EEQ37767.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) PITH PF06201.13 EEQ37768.1 - 4.6e-34 117.8 0.2 5.6e-34 117.6 0.2 1.1 1 0 0 1 1 1 1 PITH domain HAD_2 PF13419.6 EEQ37769.1 - 4.2e-16 59.5 0.0 6.7e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ37769.1 - 5.1e-11 43.3 0.6 3.5e-07 30.7 0.2 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ37769.1 - 1.1e-05 25.9 0.0 1.6e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ37769.1 - 1.6e-05 24.9 0.1 2.7e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EEQ37769.1 - 0.01 15.9 0.1 0.19 11.9 0.1 2.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NUC PF18510.1 EEQ37769.1 - 0.11 13.0 1.2 11 6.4 0.0 2.2 2 0 0 2 2 2 0 Nuclease domain IMPa_helical PF18642.1 EEQ37771.1 - 0.34 11.3 2.7 0.48 10.8 0.5 2.2 2 1 0 2 2 2 0 Immunomodulating metalloprotease helical domain FGGY_C PF02782.16 EEQ37772.1 - 2.1e-66 223.5 0.8 4.5e-66 222.4 0.6 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EEQ37772.1 - 9.1e-57 192.4 0.3 2.8e-49 167.9 0.1 3.1 1 1 1 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain UDPGP PF01704.18 EEQ37773.1 - 7.1e-41 140.2 0.0 8.9e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EEQ37773.1 - 0.0026 18.2 0.0 0.0046 17.3 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Recep_L_domain PF01030.24 EEQ37774.1 - 3.1e-08 33.7 9.2 0.062 13.4 1.4 4.6 1 1 3 4 4 4 4 Receptor L domain DUF5044 PF16447.5 EEQ37774.1 - 0.038 13.8 0.3 0.072 12.9 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5044) LRR_9 PF14580.6 EEQ37774.1 - 0.096 12.2 3.6 0.21 11.1 3.5 1.6 1 1 0 1 1 1 0 Leucine-rich repeat LRR_4 PF12799.7 EEQ37774.1 - 0.24 11.9 33.7 0.28 11.7 2.1 5.9 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) Macoilin PF09726.9 EEQ37774.1 - 3.5 6.1 16.7 5.2 5.5 16.7 1.1 1 0 0 1 1 1 0 Macoilin family AA_permease PF00324.21 EEQ37775.1 - 1e-83 281.5 44.4 1.3e-83 281.3 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ37775.1 - 2.7e-20 72.6 45.0 4e-20 72.1 45.0 1.2 1 0 0 1 1 1 1 Amino acid permease PH PF00169.29 EEQ37776.1 - 1.2e-13 51.4 0.2 7.7e-13 48.9 0.2 2.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EEQ37776.1 - 0.0016 18.8 0.3 0.0016 18.8 0.3 3.5 3 0 0 3 3 3 1 Pleckstrin homology domain Fip1 PF05182.13 EEQ37777.1 - 3.9e-23 80.7 0.4 6.4e-23 80.0 0.4 1.4 1 0 0 1 1 1 1 Fip1 motif eIF-5_eIF-2B PF01873.17 EEQ37778.1 - 8.6e-39 132.0 0.0 1.5e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EEQ37778.1 - 1.4e-25 89.2 0.1 1.4e-25 89.2 0.1 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon AbiJ_NTD5 PF18865.1 EEQ37778.1 - 0.08 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 PCI PF01399.27 EEQ37779.1 - 1.1e-12 48.3 0.5 4.5e-12 46.4 0.1 2.2 2 1 0 2 2 2 1 PCI domain Leu_Phe_trans PF03588.14 EEQ37779.1 - 0.017 14.6 0.2 1.2 8.6 0.0 2.2 1 1 1 2 2 2 0 Leucyl/phenylalanyl-tRNA protein transferase PUF PF00806.19 EEQ37780.1 - 1.4e-25 87.5 5.8 5.3e-07 29.0 0.1 6.7 6 0 0 6 6 6 6 Pumilio-family RNA binding repeat DUF4085 PF13315.6 EEQ37780.1 - 0.14 11.7 0.2 0.27 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) LRR_4 PF12799.7 EEQ37782.1 - 1.8e-14 53.6 12.0 0.35 11.4 0.1 8.0 7 2 1 8 8 8 7 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EEQ37782.1 - 1e-10 41.3 0.2 2.3e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ37782.1 - 2.6e-05 24.0 0.4 8.1e-05 22.4 0.4 1.9 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.11 EEQ37782.1 - 6.6e-05 22.6 0.6 0.91 9.2 0.0 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1699) F-box_4 PF15966.5 EEQ37782.1 - 0.00021 21.1 0.2 0.00052 19.9 0.2 1.7 1 0 0 1 1 1 1 F-box LRR_8 PF13855.6 EEQ37782.1 - 0.00083 19.1 3.5 1.4 8.7 0.0 4.8 4 1 0 4 4 4 2 Leucine rich repeat PRANC PF09372.10 EEQ37782.1 - 0.051 13.9 0.2 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 PRANC domain LRR_6 PF13516.6 EEQ37782.1 - 7.4 6.9 25.0 7.7 6.8 0.0 8.3 11 0 0 11 11 11 0 Leucine Rich repeat ESCRT-II PF05871.12 EEQ37783.1 - 1.7e-41 141.8 0.0 2.9e-41 141.0 0.0 1.4 1 1 1 2 2 2 1 ESCRT-II complex subunit CTP_synth_N PF06418.14 EEQ37784.1 - 6.3e-123 409.3 0.3 9.7e-123 408.6 0.3 1.3 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EEQ37784.1 - 6.9e-51 172.7 0.0 1.1e-50 172.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EEQ37784.1 - 0.00043 20.1 0.0 0.0044 16.8 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 DUF4090 PF13319.6 EEQ37784.1 - 0.15 12.3 0.2 0.36 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4090) CbiA PF01656.23 EEQ37784.1 - 0.18 11.9 0.0 0.23 11.5 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain TPR_2 PF07719.17 EEQ37785.1 - 1.4e-05 24.8 0.1 0.015 15.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ37785.1 - 4.5e-05 23.1 0.0 0.00085 19.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ37785.1 - 0.0025 18.3 0.2 3.8 8.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat STAT1_TAZ2bind PF12162.8 EEQ37785.1 - 0.035 13.7 0.2 0.077 12.6 0.2 1.5 1 0 0 1 1 1 0 STAT1 TAZ2 binding domain TPR_14 PF13428.6 EEQ37785.1 - 0.037 14.8 4.7 8.4 7.5 0.0 4.4 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ37785.1 - 0.055 13.7 0.0 1.9 8.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ37785.1 - 0.089 12.5 0.2 0.79 9.5 0.2 2.5 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 EEQ37785.1 - 0.11 12.9 0.2 0.87 10.1 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ37785.1 - 0.99 9.6 5.3 1 9.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_37 PF13744.6 EEQ37786.1 - 0.16 12.0 2.0 12 6.0 0.1 3.5 3 1 1 4 4 4 0 Helix-turn-helix domain Trimer_CC PF08954.11 EEQ37786.1 - 0.31 10.6 2.5 1 9.0 0.4 2.6 3 0 0 3 3 3 0 Trimerisation motif Sod_Fe_C PF02777.18 EEQ37787.1 - 4.1e-18 65.4 2.6 1.2e-16 60.8 0.9 2.7 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain TIP41 PF04176.13 EEQ37788.1 - 1e-67 226.9 0.0 1.5e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 TIP41-like family Pyr_redox_2 PF07992.14 EEQ37789.1 - 5.1e-27 94.9 2.3 6.4e-27 94.5 2.3 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ37789.1 - 6.3e-07 29.9 0.8 0.00015 22.3 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ37789.1 - 1.1e-05 24.8 0.3 0.0008 18.6 0.2 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EEQ37789.1 - 5.7e-05 23.1 2.3 3.7 7.5 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EEQ37789.1 - 0.0009 18.6 4.0 0.0017 17.7 3.2 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Eryth_link_C PF16915.5 EEQ37789.1 - 0.043 13.8 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Annelid erythrocruorin linker subunit C-terminus Usp PF00582.26 EEQ37789.1 - 0.13 12.7 0.0 0.24 11.9 0.0 1.6 1 0 0 1 1 1 0 Universal stress protein family Trp_halogenase PF04820.14 EEQ37789.1 - 0.28 10.0 5.3 2.1 7.1 0.0 3.3 4 0 0 4 4 4 0 Tryptophan halogenase DAO PF01266.24 EEQ37789.1 - 1 8.9 7.5 15 5.0 0.0 3.1 2 1 0 3 3 3 0 FAD dependent oxidoreductase MFS_1 PF07690.16 EEQ37790.1 - 6.1e-29 101.1 11.6 9.9e-29 100.4 11.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 EEQ37790.1 - 0.0018 18.4 1.4 0.0018 18.4 1.4 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3792) Amidase PF01425.21 EEQ37791.1 - 5.7e-92 309.0 0.0 7.6e-92 308.6 0.0 1.2 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 EEQ37792.1 - 2.1e-12 46.7 21.1 2.9e-12 46.2 21.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 EEQ37792.1 - 0.00053 18.0 0.0 0.0008 17.5 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Glyco_hydro81C PF17652.1 EEQ37793.1 - 1e-151 505.1 0.7 1.3e-151 504.8 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EEQ37793.1 - 1e-91 307.5 0.3 1.6e-91 306.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Arginase PF00491.21 EEQ37794.1 - 4.8e-85 285.5 0.0 7.1e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EEQ37794.1 - 0.039 14.2 0.4 0.06 13.6 0.4 1.4 1 0 0 1 1 1 0 UPF0489 domain Mitofilin PF09731.9 EEQ37795.1 - 1.3 7.7 10.9 1.6 7.5 10.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Arm PF00514.23 EEQ37796.1 - 6.9e-84 273.6 10.4 5.3e-12 45.4 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EEQ37796.1 - 1.2e-26 93.0 3.2 4.5e-26 91.1 3.2 2.1 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 EEQ37796.1 - 2.1e-21 75.2 4.3 3.8e-21 74.4 4.3 1.4 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 EEQ37796.1 - 8e-21 74.1 0.2 3.1e-07 30.8 0.0 5.7 4 1 1 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 EEQ37796.1 - 6.4e-13 48.9 0.0 0.00096 19.5 0.0 5.2 2 2 3 5 5 5 4 HEAT repeats HEAT PF02985.22 EEQ37796.1 - 1.4e-12 46.7 0.0 0.031 14.5 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 EEQ37796.1 - 0.0001 21.9 0.1 2 7.8 0.0 3.7 1 1 2 5 5 5 2 Armadillo-like RICTOR_V PF14668.6 EEQ37796.1 - 0.0002 21.5 2.3 1 9.7 0.0 4.9 4 2 2 6 6 6 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 EEQ37796.1 - 0.00024 21.2 0.0 2.3 8.3 0.0 4.0 3 1 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 EEQ37796.1 - 0.0017 17.0 0.0 0.14 10.7 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region Atx10homo_assoc PF09759.9 EEQ37796.1 - 0.009 16.0 0.0 2.6 8.1 0.0 3.7 3 1 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Rcd1 PF04078.13 EEQ37796.1 - 0.13 11.5 0.0 0.5 9.6 0.0 2.0 2 1 0 2 2 2 0 Cell differentiation family, Rcd1-like Usp PF00582.26 EEQ37798.1 - 1.1e-11 45.4 0.9 4.5e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Universal stress protein family Cytomega_UL20A PF05984.12 EEQ37798.1 - 0.027 14.8 0.3 0.07 13.4 0.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein Far-17a_AIG1 PF04750.14 EEQ37799.1 - 1.6e-18 66.7 12.5 1.8e-18 66.6 12.5 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Peptidase_M14 PF00246.24 EEQ37800.1 - 1.5e-70 238.3 0.9 2.1e-70 237.8 0.9 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Tyr_Deacylase PF02580.16 EEQ37801.1 - 6e-50 169.5 0.0 6.7e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2341 PF10102.9 EEQ37801.1 - 0.13 12.9 0.0 0.22 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) Aa_trans PF01490.18 EEQ37802.1 - 1.2e-28 100.0 34.9 1.5e-28 99.7 34.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein EMP24_GP25L PF01105.24 EEQ37803.1 - 5.5e-56 189.4 3.2 6.9e-56 189.1 3.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LPP PF04728.13 EEQ37803.1 - 0.009 16.4 2.5 0.015 15.6 2.5 1.4 1 0 0 1 1 1 1 Lipoprotein leucine-zipper Cupin_8 PF13621.6 EEQ37803.1 - 0.015 15.0 0.3 0.033 13.9 0.4 1.4 2 0 0 2 2 2 0 Cupin-like domain FlxA PF14282.6 EEQ37803.1 - 0.02 14.9 2.0 0.032 14.2 2.0 1.3 1 0 0 1 1 1 0 FlxA-like protein OsmC PF02566.19 EEQ37803.1 - 0.061 13.8 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 OsmC-like protein Shugoshin_N PF07558.11 EEQ37803.1 - 0.13 12.1 1.5 0.25 11.3 1.5 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF3450 PF11932.8 EEQ37803.1 - 0.2 11.0 1.8 0.35 10.1 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NUC153 PF08159.12 EEQ37804.1 - 5.5e-13 48.5 1.6 5.5e-13 48.5 1.6 3.0 3 1 0 3 3 3 1 NUC153 domain TLD PF07534.16 EEQ37805.1 - 3.1e-25 89.0 1.0 3.9e-23 82.2 0.9 2.4 1 1 1 2 2 2 2 TLD Kei1 PF08552.11 EEQ37806.1 - 3.9e-17 62.8 6.7 7.7e-16 58.5 6.7 2.0 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SLAC1 PF03595.17 EEQ37806.1 - 0.086 12.1 6.3 0.68 9.1 6.3 1.9 1 1 0 1 1 1 0 Voltage-dependent anion channel RIO1 PF01163.22 EEQ37807.1 - 1.9e-71 239.5 2.6 1.9e-71 239.5 2.6 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EEQ37807.1 - 0.0095 15.9 0.1 3 7.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family CDC45 PF02724.14 EEQ37807.1 - 1.2 7.3 22.5 0.024 13.0 13.7 2.0 2 0 0 2 2 2 0 CDC45-like protein SR-25 PF10500.9 EEQ37807.1 - 4.1 6.9 27.8 3.2 7.3 16.1 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein HLH PF00010.26 EEQ37808.1 - 8.6e-15 54.4 0.5 1.6e-14 53.6 0.5 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ALIX_LYPXL_bnd PF13949.6 EEQ37808.1 - 0.062 12.6 1.3 0.087 12.1 1.3 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV GRP PF07172.11 EEQ37808.1 - 0.086 13.5 7.1 0.22 12.3 7.1 1.6 1 0 0 1 1 1 0 Glycine rich protein family Peptidase_M18 PF02127.15 EEQ37809.1 - 8.9e-167 555.2 0.0 1e-166 555.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EEQ37809.1 - 3.2e-05 23.1 0.0 0.041 12.9 0.0 2.8 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase DAO PF01266.24 EEQ37811.1 - 2.4e-68 231.3 0.0 2.8e-68 231.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ37811.1 - 1.2e-06 27.9 0.1 0.0093 15.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ37811.1 - 1.5e-05 25.2 0.1 3.3e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 EEQ37811.1 - 0.00022 20.2 0.9 0.00053 18.9 0.3 1.8 2 0 0 2 2 2 1 MCRA family Thi4 PF01946.17 EEQ37811.1 - 0.0012 18.2 0.3 0.002 17.4 0.3 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 EEQ37811.1 - 0.0023 18.0 0.3 0.098 12.6 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Sacchrp_dh_NADP PF03435.18 EEQ37811.1 - 0.1 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ZZ PF00569.17 EEQ37812.1 - 1.7e-14 53.3 8.3 3e-14 52.5 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EEQ37812.1 - 2.3e-12 47.1 0.0 8.9e-12 45.2 0.0 2.0 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EEQ37812.1 - 1e-10 41.6 0.0 2.9e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ37812.1 - 2.4e-07 30.9 0.0 7.5e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Baculo_IE-1 PF05290.11 EEQ37812.1 - 0.0082 16.1 4.1 0.017 15.0 4.1 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Med25_SD1 PF11235.8 EEQ37812.1 - 0.14 12.5 0.2 0.27 11.6 0.2 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 U3_assoc_6 PF08640.11 EEQ37814.1 - 5.4e-32 109.7 3.2 3e-29 100.9 0.1 3.2 2 1 1 3 3 3 2 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EEQ37814.1 - 1.6e-09 37.8 1.1 0.00041 20.9 0.3 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat NRDE-2 PF08424.10 EEQ37814.1 - 3e-05 23.3 0.9 0.0019 17.4 0.9 2.7 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference DUF2250 PF10007.9 EEQ37814.1 - 0.00087 19.4 3.7 0.15 12.1 1.0 3.0 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2250) TPR_17 PF13431.6 EEQ37814.1 - 0.0025 18.1 0.1 4.6 7.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ37814.1 - 0.0027 18.3 0.8 0.014 16.0 0.6 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ37814.1 - 0.0042 16.8 0.6 0.41 10.4 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.17 EEQ37814.1 - 0.0059 16.6 0.5 0.085 13.0 0.1 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.14 EEQ37814.1 - 0.0084 16.1 4.7 0.0098 15.9 1.4 2.7 2 1 0 2 2 2 1 Suppressor of forked protein (Suf) AAA_assoc PF14363.6 EEQ37814.1 - 0.01 16.2 0.0 0.036 14.4 0.0 2.0 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA HAT PF02184.16 EEQ37814.1 - 0.037 14.0 0.0 2.1 8.4 0.0 2.9 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat TPR_1 PF00515.28 EEQ37814.1 - 0.072 12.9 0.0 0.28 11.1 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ37814.1 - 0.11 13.1 0.6 4.9 8.0 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat Peptidase_C78 PF07910.13 EEQ37814.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C78 MFS_1 PF07690.16 EEQ37815.1 - 2.6e-26 92.4 13.5 3.3e-26 92.1 13.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ37815.1 - 1.2e-11 43.8 1.6 1.3e-11 43.6 1.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ctr PF04145.15 EEQ37817.1 - 1.9e-20 74.0 18.4 4.7e-18 66.2 18.4 2.0 1 1 0 1 1 1 1 Ctr copper transporter family OGFr_N PF04664.13 EEQ37817.1 - 0.12 11.9 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region HIG_1_N PF04588.13 EEQ37818.1 - 2.8e-05 24.3 0.3 7.6e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2681 PF10883.8 EEQ37818.1 - 0.011 16.2 2.1 0.031 14.7 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF2569 PF10754.9 EEQ37818.1 - 0.05 14.0 1.8 0.063 13.7 0.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) ATP-synt_I PF03899.15 EEQ37818.1 - 0.88 10.0 4.2 8.6 6.8 0.7 2.4 2 1 0 2 2 2 0 ATP synthase I chain W2 PF02020.18 EEQ37820.1 - 5.1e-18 65.0 1.5 1e-17 64.0 1.5 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transferase PF00483.23 EEQ37820.1 - 3.9e-09 36.4 0.0 6.8e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EEQ37820.1 - 7.6e-06 25.4 11.2 0.11 12.3 2.0 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EEQ37820.1 - 0.00033 21.0 0.4 0.0021 18.4 0.0 2.4 2 2 0 2 2 2 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EEQ37820.1 - 0.002 16.4 0.2 0.0032 15.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) SE PF08491.10 EEQ37821.1 - 1.3e-111 372.1 0.0 1.6e-111 371.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EEQ37821.1 - 3.7e-14 52.7 0.3 2.1e-13 50.2 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EEQ37821.1 - 9.1e-08 32.1 0.6 5.8e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ37821.1 - 0.0048 17.1 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EEQ37821.1 - 0.0057 15.8 0.5 0.0057 15.8 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EEQ37821.1 - 0.011 16.2 0.6 0.027 15.0 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EEQ37821.1 - 0.026 14.4 0.2 0.042 13.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EEQ37821.1 - 0.027 13.8 0.8 0.027 13.8 0.8 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EEQ37821.1 - 0.052 13.6 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 EEQ37821.1 - 0.054 12.7 0.8 0.067 12.4 0.1 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EEQ37821.1 - 0.075 13.3 0.1 0.25 11.6 0.1 1.9 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GIDA PF01134.22 EEQ37821.1 - 0.081 12.0 0.6 0.13 11.3 0.6 1.4 1 1 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 EEQ37821.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Prp19 PF08606.11 EEQ37821.1 - 0.12 12.4 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Prp19/Pso4-like Na_Ca_ex PF01699.24 EEQ37822.1 - 6.4e-45 152.8 35.0 8.8e-23 80.9 8.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4658 PF15555.6 EEQ37822.1 - 0.23 11.6 3.6 3.9 7.6 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4658) 7tm_3 PF00003.22 EEQ37822.1 - 4.2 7.0 24.2 0.13 12.0 4.8 3.7 1 1 3 4 4 4 0 7 transmembrane sweet-taste receptor of 3 GCPR Cyclin_N PF00134.23 EEQ37823.1 - 2.5e-13 49.9 0.0 4.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EEQ37823.1 - 1.3e-08 35.3 0.7 1.8e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cpn60_TCP1 PF00118.24 EEQ37824.1 - 6.4e-141 470.3 16.5 7.2e-141 470.2 16.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Creatinase_N PF01321.18 EEQ37824.1 - 0.1 13.3 0.1 12 6.6 0.0 2.5 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Med13_C PF06333.12 EEQ37825.1 - 0.16 11.2 0.6 0.2 10.9 0.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain ketoacyl-synt PF00109.26 EEQ37826.1 - 2.7e-53 181.1 10.8 2.9e-46 158.1 4.9 2.9 2 1 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EEQ37826.1 - 3e-37 127.2 3.5 4.4e-37 126.7 0.9 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EEQ37826.1 - 5.6e-07 29.2 0.0 3.2e-05 23.4 0.1 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EEQ37826.1 - 0.07 13.0 1.8 0.39 10.6 0.4 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SKN1 PF03935.15 EEQ37827.1 - 1.1e-248 825.7 5.7 1.3e-248 825.4 5.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF4006 PF13179.6 EEQ37827.1 - 0.16 11.9 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF4006) SKN1 PF03935.15 EEQ37828.1 - 6.5e-247 819.8 8.3 7.8e-247 819.6 8.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) APG9 PF04109.16 EEQ37829.1 - 3.3e-176 587.0 23.0 3.9e-176 586.8 23.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 SAM_4 PF18017.1 EEQ37829.1 - 0.16 11.9 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Nop14 PF04147.12 EEQ37830.1 - 1.9e-166 555.8 58.5 9.6e-102 341.7 12.5 2.7 1 1 1 2 2 2 2 Nop14-like family MARVEL PF01284.23 EEQ37831.1 - 1.3e-28 99.8 20.3 1.5e-28 99.6 20.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain UPF0182 PF03699.13 EEQ37831.1 - 0.19 9.8 4.6 0.22 9.6 4.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4956 PF16316.5 EEQ37831.1 - 0.21 11.3 3.5 0.95 9.1 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4956) Ank_5 PF13857.6 EEQ37833.1 - 3.5e-37 126.0 7.6 4.3e-09 36.5 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ37833.1 - 3.6e-36 123.1 6.6 4.4e-11 43.1 0.0 4.7 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ37833.1 - 6.4e-36 122.8 0.2 2.5e-11 44.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ37833.1 - 3e-29 97.8 2.5 0.0012 19.1 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 EEQ37833.1 - 1.2e-25 88.8 13.0 0.0019 18.6 0.1 6.1 6 0 0 6 6 6 6 Ankyrin repeat Sugar_tr PF00083.24 EEQ37834.1 - 7.7e-119 397.5 19.1 9.4e-119 397.2 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ37834.1 - 2.8e-19 69.2 22.1 5.1e-14 51.9 0.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Prenyltransf PF01255.19 EEQ37835.1 - 0.0019 17.8 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase DUF5099 PF17025.5 EEQ37835.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5099) Arf PF00025.21 EEQ37836.1 - 6.7e-81 269.9 0.1 7.6e-81 269.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEQ37836.1 - 1.6e-14 54.2 0.0 2.1e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EEQ37836.1 - 3.4e-14 52.7 0.0 4.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EEQ37836.1 - 2.1e-13 50.2 0.0 2.3e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEQ37836.1 - 1.3e-12 47.6 1.0 8.9e-09 35.0 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EEQ37836.1 - 1.5e-10 40.8 0.0 1.9e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ37836.1 - 3.5e-06 27.1 0.0 5.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EEQ37836.1 - 0.0033 16.8 0.5 0.007 15.7 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase Ufd2P_core PF10408.9 EEQ37838.1 - 6.5e-184 613.0 5.1 7.6e-184 612.8 5.1 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EEQ37838.1 - 9.2e-27 93.0 0.4 3.7e-26 91.1 0.5 2.1 2 0 0 2 2 2 1 U-box domain Rho_GDI PF02115.17 EEQ37839.1 - 1.1e-56 191.7 0.3 1.2e-56 191.6 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor UvrD_C PF13361.6 EEQ37840.1 - 1.2e-52 179.4 0.0 2e-52 178.7 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 EEQ37840.1 - 1.8e-49 169.0 0.0 1.5e-48 166.0 0.0 2.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EEQ37840.1 - 1.1e-30 106.9 0.0 2.9e-30 105.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EEQ37840.1 - 4.4e-09 36.0 0.0 3e-08 33.4 0.0 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EEQ37840.1 - 1.4e-08 34.7 0.1 8.2e-06 25.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EEQ37840.1 - 1.3e-06 28.3 0.8 0.33 10.7 0.0 4.0 4 1 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EEQ37840.1 - 0.00011 22.1 2.3 0.00028 20.7 0.1 2.6 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EEQ37840.1 - 0.011 15.5 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 Helicase Band_7 PF01145.25 EEQ37842.1 - 3.6e-22 79.2 1.8 6.1e-22 78.5 1.8 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF3416 PF11896.8 EEQ37842.1 - 0.051 13.9 1.2 0.094 13.0 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) SH3_2 PF07653.17 EEQ37843.1 - 3.3e-12 45.9 0.0 4.9e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ37843.1 - 1.4e-10 40.6 0.1 2.6e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ37843.1 - 1.2e-09 37.8 0.2 3.1e-09 36.6 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain Suf PF05843.14 EEQ37843.1 - 0.33 10.9 3.5 0.55 10.2 3.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ALS_ss_C PF10369.9 EEQ37844.1 - 2.2e-17 63.0 0.2 7.5e-17 61.3 0.0 2.0 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.25 EEQ37844.1 - 6.7e-11 41.8 0.1 1.4e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EEQ37844.1 - 0.00021 21.1 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain NPCC PF08058.11 EEQ37845.1 - 0.051 13.6 0.1 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Nuclear pore complex component Zn_clus PF00172.18 EEQ37846.1 - 1.5e-09 37.8 9.5 3.4e-09 36.7 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBFD_NFYB_HMF PF00808.23 EEQ37847.1 - 2.9e-24 85.1 0.2 4.3e-24 84.6 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ37847.1 - 0.00051 20.4 1.3 0.00066 20.0 0.1 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 ASTN_2_hairpin PF18577.1 EEQ37848.1 - 0.049 13.7 0.0 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 Astrotactin-2 C-terminal beta-hairpin domain SH3_1 PF00018.28 EEQ37849.1 - 1.2e-23 82.4 0.0 6.5e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EEQ37849.1 - 1.3e-16 60.1 0.1 5.7e-10 38.9 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EEQ37849.1 - 4.7e-13 49.1 0.2 8.4e-13 48.3 0.2 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.17 EEQ37849.1 - 1.2e-10 40.9 0.0 4.5e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.24 EEQ37849.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PB1 domain Thioredoxin_4 PF13462.6 EEQ37851.1 - 1.3e-05 25.4 0.0 0.00012 22.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin tRNA_int_endo PF01974.17 EEQ37852.1 - 2.8e-26 91.4 0.1 5.9e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain CBFD_NFYB_HMF PF00808.23 EEQ37853.1 - 3.1e-15 56.2 2.0 3.1e-15 56.2 2.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ37853.1 - 4.8e-05 23.7 1.8 8.8e-05 22.9 1.8 1.5 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.14 EEQ37853.1 - 0.038 14.1 1.5 0.087 12.9 1.1 1.8 1 1 1 2 2 2 0 hTAFII28-like protein conserved region FGGY_C PF02782.16 EEQ37854.1 - 8.3e-55 185.6 0.1 1.4e-54 184.8 0.1 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EEQ37854.1 - 4.1e-19 69.1 0.0 1.1e-18 67.8 0.0 1.7 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain SOG2 PF10428.9 EEQ37854.1 - 3.1 6.9 6.9 4.7 6.3 6.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Sulfate_transp PF00916.20 EEQ37855.1 - 1.5e-118 395.9 15.0 1.9e-118 395.5 15.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEQ37855.1 - 1e-07 31.6 0.0 2.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EEQ37855.1 - 0.021 15.2 0.6 0.021 15.2 0.6 2.3 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DEAD PF00270.29 EEQ37856.1 - 6.8e-46 156.2 2.4 7.7e-46 156.1 0.9 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ37856.1 - 5.3e-33 113.7 0.7 3.4e-31 107.8 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ37856.1 - 2e-07 31.2 0.0 4.2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ37856.1 - 0.00017 22.0 0.4 0.00043 20.6 0.2 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ37856.1 - 0.00048 19.9 0.1 0.00077 19.2 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ37856.1 - 0.0039 17.5 0.1 0.011 16.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EEQ37856.1 - 0.0069 15.8 0.1 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit TniB PF05621.11 EEQ37856.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Flavi_DEAD PF07652.14 EEQ37856.1 - 0.029 14.3 0.1 0.22 11.5 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Glyco_transf_8 PF01501.20 EEQ37857.1 - 9e-15 54.9 0.0 9.5e-09 35.2 0.0 3.4 2 1 0 2 2 2 2 Glycosyl transferase family 8 tRNA_U5-meth_tr PF05958.11 EEQ37858.1 - 3.3e-10 39.5 0.4 1.5e-09 37.3 0.1 2.1 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 EEQ37858.1 - 9.1e-10 38.4 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 EEQ37858.1 - 1.2e-07 31.6 0.0 2.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ37858.1 - 9.1e-06 26.3 0.0 2e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEQ37858.1 - 1.1e-05 25.0 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EEQ37858.1 - 1.3e-05 24.9 0.2 2.8e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EEQ37858.1 - 0.00047 20.0 0.1 0.00088 19.1 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EEQ37858.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 EEQ37858.1 - 0.011 16.3 0.0 0.025 15.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ37858.1 - 0.017 14.5 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TRM PF02005.16 EEQ37858.1 - 0.079 12.1 0.7 1.8 7.6 0.0 2.4 3 0 0 3 3 3 0 N2,N2-dimethylguanosine tRNA methyltransferase PAP2 PF01569.21 EEQ37859.1 - 1.1e-17 64.0 5.8 1.1e-17 64.0 5.8 2.3 2 1 0 2 2 2 1 PAP2 superfamily Kri1 PF05178.12 EEQ37859.1 - 0.17 12.4 0.0 0.29 11.7 0.0 1.3 1 0 0 1 1 1 0 KRI1-like family Ras PF00071.22 EEQ37860.1 - 8.4e-48 162.0 0.0 1.1e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ37860.1 - 2e-22 79.6 0.0 3.2e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ37860.1 - 8.8e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF3984 PF13136.6 EEQ37860.1 - 0.021 14.3 0.6 0.034 13.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) AAA_22 PF13401.6 EEQ37860.1 - 0.078 13.2 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EEQ37860.1 - 0.088 11.9 0.0 2.2 7.4 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EEQ37860.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2401 PF10287.9 EEQ37862.1 - 2.6e-91 305.3 1.9 2.6e-91 305.3 1.9 1.9 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 EEQ37862.1 - 1.6e-29 102.1 0.1 4.7e-29 100.6 0.1 1.9 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) FGGY_C PF02782.16 EEQ37864.1 - 4.1e-10 39.7 0.5 1e-09 38.4 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EEQ37864.1 - 0.13 11.8 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Zn_clus PF00172.18 EEQ37865.1 - 1.1e-06 28.7 16.0 1.8e-06 28.0 16.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Metallophos PF00149.28 EEQ37867.1 - 3.3e-32 112.7 0.2 4.6e-32 112.2 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ChpA-C PF03777.13 EEQ37867.1 - 0.41 10.5 1.3 0.83 9.6 1.3 1.4 1 0 0 1 1 1 0 ChpA-C NAD_binding_10 PF13460.6 EEQ37869.1 - 3.5e-16 59.6 0.0 6e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ37869.1 - 1.7e-13 50.7 0.0 2.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EEQ37869.1 - 2.8e-12 46.6 0.0 6.6e-12 45.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ37869.1 - 3.4e-10 39.4 0.1 1.1e-09 37.8 0.1 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EEQ37869.1 - 1.7e-05 24.1 0.0 0.0005 19.2 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EEQ37869.1 - 0.0002 20.6 0.1 1.3 8.1 0.0 3.2 1 1 2 3 3 3 3 Male sterility protein DDE_Tnp_1_3 PF13612.6 EEQ37869.1 - 0.028 14.4 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Transposase DDE domain SRP54_N PF02881.19 EEQ37869.1 - 0.099 12.9 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain adh_short PF00106.25 EEQ37869.1 - 0.1 12.0 0.1 0.32 10.4 0.1 1.9 1 1 0 1 1 1 0 short chain dehydrogenase GTP_cyclohydro2 PF00925.20 EEQ37870.1 - 0.017 14.7 0.1 0.033 13.8 0.1 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase II Urocanase PF01175.18 EEQ37870.1 - 0.021 14.5 0.1 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 Urocanase Rossmann-like domain OHCU_decarbox PF09349.10 EEQ37871.1 - 5e-48 163.5 0.3 5.7e-48 163.3 0.3 1.0 1 0 0 1 1 1 1 OHCU decarboxylase ATP-synt_ab PF00006.25 EEQ37872.1 - 1.4e-111 371.3 0.0 2e-111 370.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EEQ37872.1 - 4.8e-45 152.3 0.0 8.6e-45 151.5 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EEQ37872.1 - 1.3e-09 38.5 1.2 3.2e-09 37.2 0.8 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Cas_St_Csn2 PF16813.5 EEQ37872.1 - 0.039 13.1 0.2 0.061 12.4 0.2 1.2 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St DUF3919 PF13057.6 EEQ37872.1 - 0.12 12.0 0.5 0.22 11.1 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3919) Mit_KHE1 PF10173.9 EEQ37874.1 - 8.6e-59 198.8 0.1 1.1e-58 198.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related MARVEL PF01284.23 EEQ37875.1 - 0.067 13.2 8.0 0.24 11.4 7.7 2.0 1 1 0 1 1 1 0 Membrane-associating domain Vma12 PF11712.8 EEQ37875.1 - 0.18 11.8 0.8 1 9.4 0.1 2.1 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase MIG-14_Wnt-bd PF06664.12 EEQ37875.1 - 0.71 9.0 9.9 2 7.6 9.9 1.6 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Cullin PF00888.22 EEQ37876.1 - 2.6e-150 502.0 6.6 2.6e-150 502.0 6.6 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EEQ37876.1 - 3.1e-23 81.6 2.6 4.7e-22 77.8 0.9 2.7 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_20 PF12840.7 EEQ37876.1 - 0.033 14.2 0.2 0.55 10.3 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_52 PF18576.1 EEQ37876.1 - 0.036 14.3 0.1 0.26 11.5 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain DUF2048 PF09752.9 EEQ37876.1 - 0.095 11.8 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Abhydrolase domain containing 18 WAC_Acf1_DNA_bd PF10537.9 EEQ37876.1 - 0.23 12.0 4.0 0.29 11.7 0.9 2.9 3 0 0 3 3 3 0 ATP-utilising chromatin assembly and remodelling N-terminal DUF5344 PF17279.2 EEQ37876.1 - 8.4 7.0 8.1 5.9 7.5 0.4 3.6 3 0 0 3 3 3 0 Family of unknown function (DUF5344) SNF2_N PF00176.23 EEQ37877.1 - 1.7e-40 138.8 0.0 1e-39 136.3 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ37877.1 - 1.8e-06 28.3 0.0 6.5e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ABC_membrane PF00664.23 EEQ37878.1 - 8.2e-53 179.8 24.1 2.8e-31 109.2 12.7 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ37878.1 - 2.9e-52 176.8 0.7 1.8e-30 106.2 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ37878.1 - 2.9e-10 40.0 10.4 3.5e-05 23.4 3.6 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EEQ37878.1 - 8.5e-07 29.1 2.7 0.027 14.6 0.2 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ37878.1 - 7.9e-06 25.9 0.3 0.0096 15.8 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EEQ37878.1 - 9.3e-05 22.1 0.9 0.38 10.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ37878.1 - 0.00024 21.4 0.3 0.13 12.5 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 EEQ37878.1 - 0.00062 19.7 4.4 0.32 10.8 0.2 3.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEQ37878.1 - 0.0012 18.7 1.0 0.83 9.3 0.3 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 EEQ37878.1 - 0.0033 17.8 0.1 2.8 8.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EEQ37878.1 - 0.0043 17.6 11.4 0.0065 17.0 0.1 3.4 3 1 0 4 4 4 1 AAA domain DUF87 PF01935.17 EEQ37878.1 - 0.0072 16.4 3.4 1 9.4 0.1 2.8 2 0 0 2 2 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 EEQ37878.1 - 0.011 16.1 0.2 4.4 7.7 0.0 3.8 4 0 0 4 4 4 0 RNA helicase TsaE PF02367.17 EEQ37878.1 - 0.014 15.4 0.8 0.16 12.0 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 EEQ37878.1 - 0.016 15.3 0.3 2.1 8.4 0.3 2.9 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.12 EEQ37878.1 - 0.028 13.7 0.4 0.93 8.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EEQ37878.1 - 0.029 14.1 1.6 0.29 10.9 0.1 2.8 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EEQ37878.1 - 0.044 13.5 1.6 9.6 5.9 0.1 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 EEQ37878.1 - 0.046 13.4 1.2 4.2 7.1 0.0 2.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EEQ37878.1 - 0.07 12.9 1.2 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pox_LP_H2 PF03356.15 EEQ37878.1 - 0.11 12.3 0.2 0.37 10.7 0.2 1.8 1 0 0 1 1 1 0 Viral late protein H2 Roc PF08477.13 EEQ37878.1 - 0.12 12.6 1.3 22 5.3 0.2 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EEQ37878.1 - 0.14 11.6 0.5 5.1 6.6 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EEQ37878.1 - 0.16 12.4 1.1 1.6 9.2 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EEQ37878.1 - 0.24 11.0 3.0 0.22 11.1 0.3 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EEQ37878.1 - 0.35 11.4 1.7 6.6 7.3 0.1 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EEQ37878.1 - 0.53 10.2 2.2 1 9.3 0.3 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 EEQ37878.1 - 0.74 9.7 2.7 0.88 9.5 0.3 2.3 2 0 0 2 2 2 0 NACHT domain GTP_EFTU PF00009.27 EEQ37878.1 - 2.5 7.6 4.9 2.7 7.5 0.3 2.7 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain BRO1 PF03097.18 EEQ37880.1 - 4e-38 131.2 0.9 4.6e-38 131.0 0.9 1.0 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EEQ37881.1 - 1.2e-31 110.1 14.1 1.2e-31 110.1 14.1 2.2 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV BRO1 PF03097.18 EEQ37881.1 - 4.5e-22 78.4 0.7 4.5e-22 78.4 0.7 2.1 3 0 0 3 3 3 1 BRO1-like domain SlyX PF04102.12 EEQ37881.1 - 0.007 17.0 2.2 6.5 7.4 0.3 3.6 2 1 0 2 2 2 2 SlyX DUF416 PF04222.12 EEQ37881.1 - 0.0074 15.7 2.5 0.025 14.0 2.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF416) LsmAD PF06741.13 EEQ37881.1 - 0.046 14.3 0.6 0.15 12.6 0.0 2.2 2 0 0 2 2 2 0 LsmAD domain Bacillus_HBL PF05791.11 EEQ37881.1 - 0.3 10.9 10.7 2.6 7.9 3.2 3.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) FadA PF09403.10 EEQ37881.1 - 3.1 8.4 14.8 11 6.6 1.7 4.9 3 2 1 4 4 4 0 Adhesion protein FadA DUF3958 PF13125.6 EEQ37881.1 - 3.6 7.8 6.9 0.9 9.8 0.2 3.3 2 1 1 4 4 4 0 Protein of unknown function (DUF3958) Glyco_hydro_16 PF00722.21 EEQ37882.1 - 2.2e-44 151.1 6.5 2.2e-44 151.1 6.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EEQ37882.1 - 1.1 9.9 13.7 2.1 8.9 13.7 1.5 1 0 0 1 1 1 0 Chitin recognition protein Coatomer_WDAD PF04053.14 EEQ37883.1 - 1.2e-133 446.5 2.8 1.2e-133 446.5 2.8 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 EEQ37883.1 - 6.3e-92 308.4 0.0 8.9e-92 307.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EEQ37883.1 - 3.7e-43 144.7 21.5 1.3e-10 41.6 1.6 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37883.1 - 1.7e-11 44.2 0.7 0.0029 17.9 0.0 5.5 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ37883.1 - 0.00012 20.9 9.6 0.2 10.3 0.1 4.2 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Metallophos PF00149.28 EEQ37884.1 - 1.1e-30 107.6 0.0 2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EEQ37884.1 - 1e-27 96.2 0.2 2.4e-27 95.1 0.2 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_1 PF00515.28 EEQ37884.1 - 1.2e-18 66.1 13.9 5.5e-07 29.1 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ37884.1 - 1.4e-17 62.3 12.4 2.2e-06 27.3 0.8 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ37884.1 - 2.2e-14 52.8 5.9 8.6e-09 34.9 0.7 2.8 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.6 EEQ37884.1 - 5.2e-10 39.8 3.0 2e-08 34.7 0.4 2.5 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ37884.1 - 6.8e-10 38.6 4.4 0.00029 21.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ37884.1 - 2.1e-09 37.7 6.0 1.2e-06 28.9 0.9 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ37884.1 - 6.4e-07 29.7 0.4 0.087 13.7 0.0 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ37884.1 - 2.8e-06 27.1 12.0 0.0049 17.0 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ37884.1 - 0.00014 22.1 4.2 0.64 10.3 0.3 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ37884.1 - 0.0004 20.5 0.0 0.0062 16.7 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ37884.1 - 0.0024 18.1 2.5 0.0024 18.1 2.5 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EEQ37884.1 - 0.0033 17.3 1.1 4 7.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ37884.1 - 0.058 14.1 1.5 2.1 9.1 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EEQ37884.1 - 0.09 12.2 0.6 1.3 8.4 0.0 2.2 1 1 1 2 2 2 0 Coatomer epsilon subunit MIT PF04212.18 EEQ37884.1 - 0.28 11.3 10.3 3.1 8.0 1.9 3.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 EEQ37884.1 - 2.5 8.2 5.2 22 5.2 0.1 3.4 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat CHCH PF06747.13 EEQ37885.1 - 1.4e-06 28.3 4.4 2.4e-06 27.5 4.4 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EEQ37885.1 - 0.22 11.6 2.7 0.5 10.4 0.2 2.1 1 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Scm3 PF10384.9 EEQ37886.1 - 2.1e-21 75.4 0.8 5.2e-21 74.1 0.8 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 dsRBD2 PF17842.1 EEQ37886.1 - 1 9.6 4.5 0.26 11.5 0.4 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 Peptidase_M41 PF01434.18 EEQ37887.1 - 4.9e-65 219.0 0.1 9.2e-65 218.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EEQ37887.1 - 1.2e-41 142.2 0.0 2.8e-41 141.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ37887.1 - 1e-09 38.0 0.2 2.2e-09 37.0 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EEQ37887.1 - 2.4e-08 34.3 0.1 7e-08 32.8 0.0 1.9 2 0 0 2 2 1 1 FtsH Extracellular TIP49 PF06068.13 EEQ37887.1 - 0.0024 17.2 0.2 0.0073 15.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_22 PF13401.6 EEQ37887.1 - 0.004 17.4 1.3 0.73 10.1 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EEQ37887.1 - 0.0048 16.9 0.6 0.063 13.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ37887.1 - 0.0072 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EEQ37887.1 - 0.019 15.1 4.0 0.049 13.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EEQ37887.1 - 0.038 13.7 0.1 0.095 12.4 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein POP1 PF06978.11 EEQ37887.1 - 0.038 14.0 1.9 0.065 13.2 1.9 1.3 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 AAA_17 PF13207.6 EEQ37887.1 - 0.041 14.3 3.5 0.16 12.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EEQ37887.1 - 0.043 14.2 3.8 0.06 13.7 0.2 2.9 2 1 1 3 3 3 0 AAA ATPase domain Chloroplast_duf PF14476.6 EEQ37888.1 - 0.092 11.7 0.1 0.15 11.0 0.1 1.3 1 0 0 1 1 1 0 Petal formation-expressed Glyco_transf_15 PF01793.16 EEQ37889.1 - 3.3e-135 450.5 4.7 4.1e-135 450.2 4.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.16 EEQ37890.1 - 5e-134 446.6 3.9 6.2e-134 446.3 3.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RabGAP-TBC PF00566.18 EEQ37891.1 - 3e-36 125.1 1.3 5e-36 124.4 1.3 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NPL4 PF05021.15 EEQ37892.1 - 1.8e-128 428.2 0.0 2.2e-128 427.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EEQ37892.1 - 3.2e-54 183.0 0.1 7.7e-54 181.8 0.0 1.7 2 0 0 2 2 2 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EEQ37892.1 - 5.2e-06 26.9 0.0 9.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 HSP70 PF00012.20 EEQ37893.1 - 1.1e-169 565.5 5.8 1.1e-169 565.5 5.8 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ37893.1 - 3e-13 49.3 0.2 3.4e-12 45.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein NLE PF08154.12 EEQ37893.1 - 0.13 12.8 0.0 0.41 11.2 0.0 1.9 1 0 0 1 1 1 0 NLE (NUC135) domain Pkinase PF00069.25 EEQ37894.1 - 4.3e-23 82.0 0.1 6.5e-23 81.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37894.1 - 6.5e-11 42.0 0.2 9.4e-11 41.5 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4744 PF15918.5 EEQ37894.1 - 0.73 10.7 8.4 0.16 12.8 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4744) Radical_SAM_C PF16199.5 EEQ37895.1 - 1.1e-32 111.8 0.0 2.2e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EEQ37895.1 - 9.5e-18 65.1 0.2 3.2e-17 63.4 0.0 2.0 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EEQ37895.1 - 3.2e-09 37.0 0.1 6.2e-09 36.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ37895.1 - 5.5e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ37895.1 - 0.017 15.5 0.1 0.039 14.4 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AA_permease PF00324.21 EEQ37896.1 - 2.1e-103 346.5 37.5 2.6e-103 346.2 37.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ37896.1 - 9.1e-24 84.1 39.5 1.1e-23 83.8 39.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1148 PF06618.11 EEQ37897.1 - 0.048 13.8 0.9 0.32 11.1 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1148) MBA1 PF07961.11 EEQ37898.1 - 1.5e-68 230.4 0.1 1.9e-68 230.1 0.1 1.0 1 0 0 1 1 1 1 MBA1-like protein zf-CCCH_4 PF18044.1 EEQ37899.1 - 8.8e-11 41.3 11.8 3.6e-05 23.4 1.5 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EEQ37899.1 - 9.9e-11 41.3 10.2 1e-05 25.3 2.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ37899.1 - 9.8e-08 31.8 17.7 1.9e-05 24.5 3.4 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EEQ37899.1 - 3.5e-06 27.7 14.4 0.0019 18.9 0.3 3.3 1 1 2 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 EEQ37899.1 - 0.0001 22.5 1.4 0.00024 21.3 1.1 1.6 1 1 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EEQ37899.1 - 0.048 14.1 13.5 0.88 10.1 3.2 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger NOG1_N PF17835.1 EEQ37901.1 - 4.5e-50 169.7 3.1 1.1e-49 168.5 0.1 2.5 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EEQ37901.1 - 5.3e-26 90.2 1.1 1.6e-25 88.7 0.2 2.2 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EEQ37901.1 - 2.6e-25 88.2 1.4 6.4e-25 86.9 1.4 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EEQ37901.1 - 1.4e-16 60.6 0.0 9.8e-16 57.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ37901.1 - 1.3e-09 37.8 0.1 2.8e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEQ37901.1 - 0.0041 17.1 0.1 1.9 8.4 0.2 2.9 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EEQ37901.1 - 0.033 14.2 0.4 8 6.5 0.0 3.1 2 1 1 3 3 3 0 Dynamin family AAA_16 PF13191.6 EEQ37901.1 - 0.036 14.4 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EEQ37901.1 - 0.044 14.0 0.1 0.44 10.8 0.0 2.7 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Telomere_reg-2 PF10193.9 EEQ37901.1 - 0.16 12.5 0.5 3.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Telomere length regulation protein AAA_23 PF13476.6 EEQ37901.1 - 0.4 11.1 0.0 0.4 11.1 0.0 2.6 2 1 0 2 2 1 0 AAA domain Anp1 PF03452.14 EEQ37902.1 - 4.3e-59 200.1 0.0 5.3e-59 199.8 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 EEQ37902.1 - 0.0087 15.9 0.0 0.019 14.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_8 PF01501.20 EEQ37902.1 - 0.0098 15.5 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 EF1G PF00647.19 EEQ37903.1 - 4.6e-44 148.8 0.3 8.6e-44 148.0 0.3 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EEQ37903.1 - 2.5e-11 43.6 0.2 2.5e-11 43.6 0.2 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ37903.1 - 7.5e-09 35.5 0.4 1.7e-08 34.4 0.4 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ37903.1 - 6.6e-05 23.0 0.2 6.6e-05 23.0 0.2 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 EEQ37904.1 - 5.7e-05 23.1 9.5 0.00012 22.1 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ37905.1 - 4.8e-09 35.7 0.0 1.2e-08 34.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ37905.1 - 0.00022 21.3 9.9 0.00041 20.4 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavoprotein PF02441.19 EEQ37910.1 - 1.9e-50 170.7 0.4 2.6e-50 170.3 0.4 1.2 1 0 0 1 1 1 1 Flavoprotein PPP4R2 PF09184.11 EEQ37910.1 - 0.058 13.0 10.0 0.11 12.1 10.0 1.4 1 0 0 1 1 1 0 PPP4R2 Sigma70_ner PF04546.13 EEQ37910.1 - 1.4 8.8 12.8 2.6 7.9 12.8 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region TLP-20 PF06088.11 EEQ37910.1 - 1.8 8.5 10.2 3.7 7.4 10.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SDA1 PF05285.12 EEQ37910.1 - 2.6 7.4 20.0 4 6.8 20.0 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EEQ37910.1 - 3.8 5.6 21.9 5.4 5.1 21.9 1.1 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 EEQ37910.1 - 9.6 6.4 20.7 17 5.6 20.7 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_L1 PF00687.21 EEQ37911.1 - 6.7e-41 140.3 1.1 8.6e-41 139.9 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family FtsJ PF01728.19 EEQ37912.1 - 1.3e-22 80.7 0.0 1.8e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF5477 PF17571.2 EEQ37912.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5477) Coatomer_WDAD PF04053.14 EEQ37914.1 - 2.9e-165 550.7 5.1 4.9e-165 549.9 5.1 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EEQ37914.1 - 3.5e-37 125.7 5.0 1.7e-06 28.6 0.0 9.3 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37914.1 - 9.9e-09 35.4 1.1 4.5 7.6 0.0 7.1 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EEQ37914.1 - 0.00054 20.0 0.1 1.2 9.2 0.0 4.6 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region MetallophosC PF16370.5 EEQ37914.1 - 0.002 18.4 0.9 0.011 16.0 0.0 2.5 2 1 1 3 3 3 1 C terminal of Calcineurin-like phosphoesterase Nup160 PF11715.8 EEQ37914.1 - 0.0085 14.8 6.9 0.089 11.4 0.1 3.8 2 2 1 5 5 5 2 Nucleoporin Nup120/160 ALG11_N PF15924.5 EEQ37915.1 - 1.1e-70 238.0 0.2 1.6e-70 237.4 0.2 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EEQ37915.1 - 2e-13 50.2 0.0 5.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_M24 PF00557.24 EEQ37917.1 - 9.4e-46 156.1 0.2 1.2e-45 155.8 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Aa_trans PF01490.18 EEQ37918.1 - 2.3e-90 303.2 12.0 2.8e-90 303.0 12.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EEQ37918.1 - 4.1e-08 32.7 11.7 4.1e-08 32.7 11.7 1.7 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family AOX PF01786.17 EEQ37919.1 - 2.6e-89 298.4 0.3 3.1e-89 298.2 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 EEQ37919.1 - 0.00083 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 DUF4248 PF14053.6 EEQ37919.1 - 0.15 12.1 0.1 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) SH3_9 PF14604.6 EEQ37920.1 - 2.7e-09 36.7 0.0 5.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ37920.1 - 1.1e-07 31.3 0.1 1.9e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ37920.1 - 1.2e-06 28.1 0.0 2.6e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain UPF0061 PF02696.14 EEQ37923.1 - 7.3e-127 424.0 0.0 9.7e-127 423.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family KilA-N PF04383.13 EEQ37924.1 - 2.8e-05 23.9 0.8 0.00027 20.8 0.0 2.5 2 1 0 2 2 2 1 KilA-N domain DUF782 PF05614.11 EEQ37925.1 - 0.016 15.6 0.4 0.016 15.6 0.4 2.1 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF782) Suc_Fer-like PF06999.12 EEQ37926.1 - 1.6e-46 158.7 0.0 1.8e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like SNF2_N PF00176.23 EEQ37927.1 - 8.4e-68 228.6 0.0 1.5e-67 227.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ37927.1 - 7.1e-19 68.2 0.0 1.8e-18 66.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ37927.1 - 3.9e-06 27.0 3.5 1.5e-05 25.1 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Gpr1_Fun34_YaaH PF01184.19 EEQ37928.1 - 7.8e-91 303.3 20.7 9e-91 303.1 20.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family adh_short PF00106.25 EEQ37929.1 - 8.7e-41 139.5 0.2 1.1e-40 139.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ37929.1 - 1.1e-32 113.5 0.2 1.4e-32 113.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ37929.1 - 5.9e-06 26.3 0.1 1.1e-05 25.5 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ37929.1 - 0.038 13.5 0.4 0.16 11.4 0.4 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 EEQ37930.1 - 7.7e-57 192.6 0.0 5.9e-56 189.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ37930.1 - 2.2e-27 96.0 0.0 1.2e-19 70.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EEQ37930.1 - 2.1e-05 25.1 0.7 6.2e-05 23.6 0.7 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EEQ37930.1 - 0.00012 21.5 0.0 0.0092 15.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEQ37930.1 - 0.0013 17.7 0.0 0.0035 16.3 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEQ37930.1 - 0.0027 17.1 0.1 0.0053 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ37930.1 - 0.0032 17.4 0.4 0.026 14.4 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEQ37930.1 - 0.13 11.0 0.1 0.25 10.1 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase Mif2_N PF15624.6 EEQ37930.1 - 0.16 12.7 1.5 0.33 11.7 1.5 1.5 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal RNase_PH PF01138.21 EEQ37932.1 - 7.7e-18 65.3 0.1 1.3e-17 64.6 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF1997 PF09366.10 EEQ37932.1 - 0.064 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1997) Nop PF01798.18 EEQ37933.1 - 1.1e-23 83.9 0.0 2.5e-23 82.8 0.0 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin tRNA-synt_1 PF00133.22 EEQ37934.1 - 1e-230 767.1 1.8 1.5e-229 763.3 1.8 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EEQ37934.1 - 2.4e-35 121.7 0.2 6.6e-35 120.3 0.2 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EEQ37934.1 - 4.4e-14 52.0 1.9 3e-07 29.5 0.1 4.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EEQ37934.1 - 4.9e-12 45.7 9.8 8.8e-08 31.9 0.0 3.5 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EEQ37934.1 - 0.29 10.4 0.0 0.29 10.4 0.0 3.5 3 1 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Connexin PF00029.19 EEQ37934.1 - 2.3 7.9 3.9 4.4 7.0 3.9 1.4 1 0 0 1 1 1 0 Connexin CDT1_C PF16679.5 EEQ37935.1 - 6.7e-14 52.1 0.1 2.1e-13 50.5 0.1 1.9 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain IspD PF01128.19 EEQ37935.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Lamprin PF06403.11 EEQ37937.1 - 0.1 12.5 0.2 0.18 11.8 0.2 1.3 1 0 0 1 1 1 0 Lamprin E1-E2_ATPase PF00122.20 EEQ37938.1 - 3.2e-18 65.9 0.0 6.1e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ37938.1 - 1.6e-10 41.7 0.5 2.2e-09 37.9 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ37938.1 - 7.4e-07 29.2 0.1 2e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DIOX_N PF14226.6 EEQ37939.1 - 1.4e-31 109.7 0.1 1.3e-30 106.6 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EEQ37939.1 - 5.6e-14 52.5 0.0 9.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ALMT PF11744.8 EEQ37941.1 - 1.3 7.8 11.3 1 8.1 10.4 1.3 1 1 0 1 1 1 0 Aluminium activated malate transporter O-antigen_lig PF13425.6 EEQ37941.1 - 7 5.3 6.7 7.9 5.2 6.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein MutL_C PF08676.11 EEQ37943.1 - 2.8e-12 46.6 0.1 1.3e-11 44.4 0.1 2.2 1 1 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EEQ37943.1 - 2e-07 30.9 0.0 4.6e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EEQ37943.1 - 2.3e-07 31.3 0.0 5.4e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NPCC PF08058.11 EEQ37944.1 - 6.1e-34 116.9 1.3 2.2e-33 115.1 0.1 2.2 2 0 0 2 2 2 1 Nuclear pore complex component CytochromB561_N PF09786.9 EEQ37944.1 - 0.017 14.2 0.5 0.022 13.8 0.0 1.4 2 0 0 2 2 2 0 Cytochrome B561, N terminal 4HBT_3 PF13622.6 EEQ37946.1 - 1.9e-37 129.8 0.1 2.4e-37 129.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EEQ37946.1 - 1.1e-14 54.4 3.3 2.7e-07 30.5 0.3 3.9 3 1 1 4 4 4 3 Acyl-CoA thioesterase 4HBT_3 PF13622.6 EEQ37947.1 - 6.5e-40 137.9 0.0 7.9e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EEQ37947.1 - 6e-15 55.3 0.3 4.2e-10 39.6 0.2 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 EEQ37948.1 - 7.3e-37 128.0 0.0 1.3e-36 127.2 0.0 1.3 1 1 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EEQ37948.1 - 7.9e-08 32.2 0.0 7.3e-05 22.6 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase RXT2_N PF08595.11 EEQ37948.1 - 0.024 14.7 4.4 0.038 14.0 4.4 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 EEQ37948.1 - 0.041 12.0 11.9 0.055 11.6 11.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2076 PF09849.9 EEQ37948.1 - 0.043 13.9 1.1 0.063 13.3 1.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) NOA36 PF06524.12 EEQ37948.1 - 0.055 12.8 7.4 0.092 12.1 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 EEQ37948.1 - 0.12 12.1 4.3 0.18 11.6 4.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.6 EEQ37948.1 - 0.14 11.8 4.5 0.22 11.2 4.5 1.3 1 0 0 1 1 1 0 FAM176 family DUF3246 PF11596.8 EEQ37948.1 - 0.25 10.8 1.6 0.34 10.3 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.14 EEQ37948.1 - 0.33 9.2 4.0 0.4 8.9 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 EEQ37948.1 - 0.55 10.5 6.6 1 9.6 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cwf_Cwc_15 PF04889.12 EEQ37948.1 - 0.97 9.1 15.7 1.5 8.5 15.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 EEQ37948.1 - 1.7 7.7 14.2 2.4 7.2 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 EEQ37948.1 - 5.2 7.5 18.3 1.4 9.4 14.5 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sec1 PF00995.23 EEQ37949.1 - 3e-60 205.0 6.9 3.9e-60 204.7 6.9 1.1 1 0 0 1 1 1 1 Sec1 family DUF4709 PF15821.5 EEQ37949.1 - 0.48 10.7 6.8 0.36 11.1 4.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4709) COX7C PF02935.16 EEQ37951.1 - 3.7e-24 84.8 2.5 4.2e-24 84.6 2.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc CTD_bind PF04818.13 EEQ37953.1 - 0.0013 19.5 0.3 0.0041 17.9 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. PreAtp-grasp PF18604.1 EEQ37953.1 - 0.012 15.2 0.7 2.2 7.9 0.0 3.7 4 1 1 5 5 5 0 Pre ATP-grasp domain VHS PF00790.19 EEQ37953.1 - 0.031 14.1 0.0 0.088 12.7 0.0 1.8 2 0 0 2 2 2 0 VHS domain SpoVR PF04293.13 EEQ37953.1 - 0.094 11.4 0.2 0.16 10.6 0.2 1.3 1 0 0 1 1 1 0 SpoVR like protein Iso_dh PF00180.20 EEQ37954.1 - 6.9e-74 249.1 0.0 7.9e-74 248.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF5315 PF17242.2 EEQ37955.1 - 0.068 13.0 0.1 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Disordered region of unknown function (DUF5315) GP79 PF17463.2 EEQ37957.1 - 0.14 12.2 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Gene product 79 COG6 PF06419.11 EEQ37960.1 - 2.7e-141 471.9 10.9 3.6e-141 471.5 10.9 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF948 PF06103.11 EEQ37960.1 - 0.85 9.9 3.9 86 3.5 0.0 4.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Diphthamide_syn PF01866.17 EEQ37961.1 - 1.5e-116 389.1 0.1 3.8e-116 387.8 0.0 1.6 2 0 0 2 2 2 1 Putative diphthamide synthesis protein SHQ1 PF04925.15 EEQ37962.1 - 5.9e-66 221.4 0.0 8.1e-66 220.9 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1_CS PF18201.1 EEQ37962.1 - 0.0038 17.6 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 PIH1 CS-like domain DUF3113 PF11310.8 EEQ37962.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) DUF2722 PF10846.8 EEQ37963.1 - 8.3e-82 275.6 26.2 1.7e-81 274.6 26.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) Neisseria_TspB PF05616.13 EEQ37963.1 - 7.7 4.9 8.4 14 4.0 8.4 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein ADH_N PF08240.12 EEQ37964.1 - 0.0023 17.8 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain bZIP_1 PF00170.21 EEQ37964.1 - 3.4 7.8 5.7 1.4 9.1 2.1 2.1 2 0 0 2 2 2 0 bZIP transcription factor LMBR1 PF04791.16 EEQ37965.1 - 1.8e-70 238.3 25.6 2.2e-70 238.1 25.6 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein ALIX_LYPXL_bnd PF13949.6 EEQ37965.1 - 0.0003 20.2 2.1 0.00053 19.4 0.6 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV ABC_tran PF00005.27 EEQ37966.1 - 2.2e-44 151.3 6.3 1.8e-21 77.1 0.1 3.4 4 1 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EEQ37966.1 - 3.1e-21 75.2 4.6 3.1e-21 75.2 4.6 4.4 5 0 0 5 5 5 1 ABC transporter AAA_21 PF13304.6 EEQ37966.1 - 2.2e-14 54.0 7.8 0.0021 17.9 0.0 5.2 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ37966.1 - 5.4e-10 39.1 0.8 0.00044 19.8 0.0 3.6 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EEQ37966.1 - 2.1e-06 27.8 0.0 0.068 13.1 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_18 PF13238.6 EEQ37966.1 - 8e-06 26.4 0.1 0.061 13.9 0.1 3.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EEQ37966.1 - 1.2e-05 24.9 0.3 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EEQ37966.1 - 1.4e-05 25.4 2.5 0.071 13.3 0.2 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EEQ37966.1 - 1.6e-05 25.4 0.1 0.036 14.5 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EEQ37966.1 - 0.00011 22.4 2.8 0.33 11.2 0.2 3.6 2 2 1 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EEQ37966.1 - 0.00016 21.7 1.1 0.12 12.5 0.1 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.29 EEQ37966.1 - 0.00018 21.9 1.8 0.71 10.3 0.1 4.1 4 1 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EEQ37966.1 - 0.00026 20.8 0.0 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EEQ37966.1 - 0.0003 21.4 25.0 0.098 13.2 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_14 PF13173.6 EEQ37966.1 - 0.00034 20.6 0.9 0.0097 15.9 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ37966.1 - 0.001 18.8 0.1 4 7.1 0.1 3.9 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EEQ37966.1 - 0.0016 18.6 4.1 0.4 10.8 0.0 3.3 3 1 0 3 3 2 2 AAA domain ATP-synt_ab PF00006.25 EEQ37966.1 - 0.0021 17.7 0.0 0.033 13.8 0.0 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 EEQ37966.1 - 0.0023 17.9 0.5 0.84 9.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 EEQ37966.1 - 0.0029 17.1 0.0 1.2 8.6 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EEQ37966.1 - 0.0073 16.7 0.0 6.9 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase PduV-EutP PF10662.9 EEQ37966.1 - 0.013 15.2 0.2 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 EEQ37966.1 - 0.018 14.9 0.3 0.52 10.2 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.6 EEQ37966.1 - 0.02 14.6 27.4 0.081 12.6 0.0 5.1 3 1 1 4 4 4 0 AAA ATPase domain Pox_A32 PF04665.12 EEQ37966.1 - 0.02 14.3 1.3 0.57 9.6 0.0 3.1 3 0 0 3 3 3 0 Poxvirus A32 protein Roc PF08477.13 EEQ37966.1 - 0.042 14.0 0.1 6.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 EEQ37966.1 - 0.063 12.3 0.0 0.38 9.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 EEQ37966.1 - 0.095 12.8 0.2 0.095 12.8 0.2 3.8 3 2 1 4 4 4 0 Dynamin family TsaE PF02367.17 EEQ37966.1 - 0.1 12.6 0.1 11 6.0 0.1 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EEQ37966.1 - 0.27 10.8 2.8 12 5.4 0.1 3.6 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain Tup_N PF08581.10 EEQ37966.1 - 0.48 10.8 7.4 0.53 10.6 2.1 2.7 2 0 0 2 2 2 0 Tup N-terminal AAA_5 PF07728.14 EEQ37966.1 - 0.71 9.9 2.6 5.6 7.0 0.2 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF812 PF05667.11 EEQ37966.1 - 0.93 8.3 14.3 0.11 11.3 9.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF812) Lactamase_B_2 PF12706.7 EEQ37967.1 - 3.8e-30 104.9 0.0 5.8e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EEQ37967.1 - 6.2e-14 52.2 0.0 1.1e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEQ37967.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Romo1 PF10247.9 EEQ37968.1 - 1.5e-26 92.5 11.4 2e-26 92.1 11.4 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 DUF1690 PF07956.11 EEQ37969.1 - 1.7e-43 148.4 5.2 1.9e-43 148.2 5.2 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) Spore_GerAC PF05504.11 EEQ37969.1 - 0.091 13.0 1.3 0.13 12.4 0.7 1.5 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal UCH PF00443.29 EEQ37970.1 - 1.2e-44 152.7 1.1 1.9e-44 152.1 1.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ37970.1 - 1.8e-12 47.5 11.1 5.5e-08 32.8 6.0 2.3 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EEQ37970.1 - 3.5e-09 36.3 0.3 1.1e-08 34.7 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 EEQ37970.1 - 0.0034 16.9 0.2 1.3 8.5 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin-specific peptidase-like, SUMO isopeptidase TBK1_ULD PF18396.1 EEQ37970.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Aldedh PF00171.22 EEQ37971.1 - 6.1e-82 275.6 0.1 7.2e-82 275.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 EEQ37973.1 - 3.3e-06 27.7 0.0 0.07 14.0 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ37973.1 - 8.2e-05 22.8 0.0 0.17 12.2 0.0 4.0 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 EEQ37973.1 - 0.072 13.0 0.6 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Ge1_WD40 PF16529.5 EEQ37973.1 - 0.12 11.3 0.2 0.67 8.9 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC5 PF12862.7 EEQ37974.1 - 5.8e-31 106.4 4.0 1.8e-30 104.9 4.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 Cohesin_load PF10345.9 EEQ37974.1 - 0.00046 18.8 6.4 0.00053 18.6 0.7 2.6 3 0 0 3 3 3 2 Cohesin loading factor Lzipper-MIP1 PF14389.6 EEQ37974.1 - 0.038 14.3 0.2 0.13 12.5 0.2 1.9 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TPR_12 PF13424.6 EEQ37974.1 - 0.044 14.1 1.0 1 9.7 0.3 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.21 EEQ37975.1 - 8.4e-13 48.9 0.5 8.4e-13 48.9 0.5 2.7 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RCC1_2 PF13540.6 EEQ37976.1 - 9.8e-19 66.7 7.6 7.5e-10 38.3 0.0 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EEQ37976.1 - 1.5e-15 57.6 8.0 0.00013 22.5 0.0 6.3 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat F-box PF00646.33 EEQ37976.1 - 0.0012 18.6 0.1 0.0038 17.1 0.0 1.9 2 0 0 2 2 2 1 F-box domain ORMDL PF04061.14 EEQ37977.1 - 1.1e-54 183.9 3.2 1.3e-54 183.6 3.2 1.0 1 0 0 1 1 1 1 ORMDL family SHMT PF00464.19 EEQ37978.1 - 3.3e-209 694.4 0.0 3.9e-209 694.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EEQ37978.1 - 3.5e-06 26.4 0.0 9.9e-06 24.9 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EEQ37978.1 - 0.0035 16.6 0.0 0.0063 15.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EEQ37978.1 - 0.041 12.4 0.0 0.069 11.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glutaredoxin PF00462.24 EEQ37979.1 - 2.5e-08 34.0 0.0 4.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 EEQ37979.1 - 0.0011 19.3 0.1 0.002 18.5 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain DUF600 PF04634.12 EEQ37979.1 - 0.0051 16.9 0.4 0.006 16.7 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF600 Thioredoxin_7 PF13899.6 EEQ37979.1 - 0.043 14.0 0.1 0.069 13.3 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.6 EEQ37979.1 - 0.051 13.3 0.1 0.14 12.0 0.1 1.7 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.6 EEQ37979.1 - 0.09 12.9 0.1 0.15 12.2 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin Hexokinase_1 PF00349.21 EEQ37980.1 - 3e-74 249.2 0.0 5e-74 248.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EEQ37980.1 - 2.3e-71 240.0 0.0 3e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase DUF1769 PF08588.10 EEQ37982.1 - 2.6e-22 78.8 0.1 4.3e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) TAL_FSA PF00923.19 EEQ37983.1 - 2.8e-97 325.5 0.3 3.2e-97 325.3 0.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Flavokinase PF01687.17 EEQ37984.1 - 4.6e-26 91.3 0.0 5.2e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Na_Ca_ex PF01699.24 EEQ37985.1 - 3.1e-31 108.4 42.1 4.5e-20 72.1 9.6 3.3 3 0 0 3 3 3 3 Sodium/calcium exchanger protein adh_short PF00106.25 EEQ37987.1 - 8.1e-51 172.3 0.0 1.1e-50 171.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ37987.1 - 1.6e-32 113.0 0.1 2e-32 112.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ37987.1 - 1.5e-11 44.5 0.0 2.3e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EEQ37987.1 - 0.00043 19.7 0.0 0.0017 17.8 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EEQ37987.1 - 0.0017 18.3 0.1 0.003 17.5 0.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EEQ37987.1 - 0.0042 16.2 0.1 0.0065 15.6 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.21 EEQ37987.1 - 0.085 12.2 0.3 2 7.7 0.1 2.2 2 0 0 2 2 2 0 ThiF family Epimerase PF01370.21 EEQ37987.1 - 0.12 11.8 0.1 0.27 10.7 0.0 1.9 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EEQ37987.1 - 0.13 12.5 0.2 0.34 11.2 0.1 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF4829 PF16111.5 EEQ37987.1 - 0.14 12.9 0.1 0.63 10.8 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4829) Ribosomal_L18A PF01775.17 EEQ37989.1 - 7.1e-53 177.8 0.8 7.1e-53 177.8 0.8 1.4 1 1 1 2 2 2 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A FA_hydroxylase PF04116.13 EEQ37990.1 - 2.3e-24 86.2 21.0 2.3e-24 86.2 21.0 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase PF00117.28 EEQ37991.1 - 9.3e-46 156.0 0.0 1.2e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EEQ37991.1 - 1e-44 151.5 0.0 1.7e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EEQ37991.1 - 0.00011 22.0 0.5 0.0037 17.0 0.0 2.6 1 1 1 3 3 3 1 Peptidase C26 Bul1_N PF04425.12 EEQ37992.1 - 6.1e-133 443.9 2.0 8.2e-133 443.5 0.1 1.9 1 1 1 2 2 2 1 Bul1 N terminus Bul1_C PF04426.12 EEQ37992.1 - 3.6e-16 59.4 0.8 2.9e-10 40.0 0.5 2.4 1 1 0 2 2 2 2 Bul1 C terminus DWNN PF08783.11 EEQ37993.1 - 2.2e-24 85.5 0.0 6.3e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EEQ37993.1 - 1.2e-07 31.4 7.3 2.6e-07 30.3 7.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EEQ37993.1 - 0.00029 20.8 2.0 0.00029 20.8 2.0 2.1 2 0 0 2 2 2 1 Zinc knuckle Zn_Tnp_IS1595 PF12760.7 EEQ37993.1 - 0.017 15.1 0.2 0.61 10.1 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CCHC_5 PF14787.6 EEQ37993.1 - 0.032 14.0 2.3 0.14 11.9 0.3 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EEQ37993.1 - 0.084 12.9 0.3 0.24 11.4 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1610 PF07754.11 EEQ37993.1 - 0.35 10.9 2.8 0.94 9.5 2.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Nup160 PF11715.8 EEQ37994.1 - 2.8e-42 145.1 6.9 4e-42 144.6 6.9 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Prefoldin_3 PF13758.6 EEQ37994.1 - 0.022 14.8 0.1 0.57 10.3 0.0 2.6 2 0 0 2 2 2 0 Prefoldin subunit TFIIA_gamma_C PF02751.14 EEQ37995.1 - 6.6e-24 83.8 3.9 1e-23 83.2 3.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EEQ37995.1 - 2.1e-23 82.1 0.2 2.9e-23 81.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TAP42 PF04177.12 EEQ37996.1 - 5.2e-82 275.5 13.9 6.2e-82 275.3 13.9 1.1 1 0 0 1 1 1 1 TAP42-like family Spore_YpjB PF09577.10 EEQ37996.1 - 0.011 15.5 3.2 0.017 14.9 0.1 2.4 2 1 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Orthopox_A49R PF06489.11 EEQ37996.1 - 0.022 15.0 0.1 2.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Orthopoxvirus A49R protein DUF4298 PF14131.6 EEQ37996.1 - 0.036 14.0 2.0 0.27 11.2 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) zf-RING_9 PF13901.6 EEQ37996.1 - 0.18 11.8 2.2 0.13 12.2 0.2 1.7 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Glyco_hydro_3_C PF01915.22 EEQ37997.1 - 1.5e-62 211.2 0.0 2.5e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EEQ37997.1 - 3.2e-47 161.5 0.0 4.8e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EEQ37997.1 - 6.3e-22 77.5 3.6 1.5e-21 76.3 1.2 2.5 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.12 EEQ37997.1 - 7.9e-21 74.4 0.0 1.6e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EEQ37997.1 - 0.0054 17.1 0.0 0.026 14.9 0.0 2.2 2 0 0 2 2 2 1 GLEYA domain DUF89 PF01937.19 EEQ37998.1 - 3.4e-113 378.2 3.7 3.8e-113 378.0 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 CUE PF02845.16 EEQ37999.1 - 2.6e-09 36.6 0.2 4.5e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 CUE domain Apolipoprotein PF01442.18 EEQ38000.1 - 1.7e-10 41.1 68.8 1.5e-06 28.2 30.0 3.7 1 1 4 5 5 5 4 Apolipoprotein A1/A4/E domain Phasin_2 PF09361.10 EEQ38000.1 - 0.0047 17.2 15.1 0.0047 17.2 15.1 6.4 1 1 4 6 6 6 5 Phasin protein Bromo_TP PF07524.13 EEQ38000.1 - 0.018 15.0 0.8 2.2 8.3 0.1 3.3 2 0 0 2 2 2 0 Bromodomain associated DUF883 PF05957.13 EEQ38000.1 - 0.22 12.1 85.6 0.061 13.9 5.7 8.0 2 1 5 7 7 7 0 Bacterial protein of unknown function (DUF883) Mucin-like PF16058.5 EEQ38000.1 - 5.7 7.1 9.5 0.31 11.1 0.3 2.9 2 2 0 2 2 2 0 Mucin-like TTL PF03133.15 EEQ38001.1 - 2.3e-59 201.0 0.0 3.7e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EEQ38001.1 - 1e-45 155.9 0.0 1.8e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EEQ38001.1 - 0.0019 17.5 0.1 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 YheC/D like ATP-grasp DUF4786 PF16027.5 EEQ38001.1 - 0.068 13.7 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) ATP-grasp_3 PF02655.14 EEQ38001.1 - 0.13 12.3 0.0 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain zf-Tim10_DDP PF02953.15 EEQ38002.1 - 6.6e-16 57.7 0.6 9.4e-16 57.2 0.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Wyosine_form PF08608.12 EEQ38002.1 - 0.012 15.9 0.1 0.021 15.1 0.1 1.4 1 0 0 1 1 1 0 Wyosine base formation F_bP_aldolase PF01116.20 EEQ38003.1 - 3.2e-91 305.7 0.0 3.6e-91 305.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Acetyltransf_1 PF00583.25 EEQ38004.1 - 1.9e-17 63.5 0.0 2.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EEQ38004.1 - 1.4e-10 41.0 0.0 2.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EEQ38004.1 - 1.5e-10 41.4 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ38004.1 - 2.7e-10 40.2 0.0 4.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EEQ38004.1 - 4e-07 30.8 0.0 5.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EEQ38004.1 - 9e-07 28.7 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EEQ38004.1 - 0.002 17.6 0.0 0.0027 17.2 0.0 1.5 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 EEQ38004.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EEQ38004.1 - 0.014 15.5 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EEQ38004.1 - 0.015 15.5 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RXT2_N PF08595.11 EEQ38005.1 - 1.3e-37 129.2 0.2 1.3e-37 129.2 0.2 2.6 2 0 0 2 2 2 1 RXT2-like, N-terminal Tetrabrachion PF11401.8 EEQ38005.1 - 0.1 12.6 0.2 0.25 11.4 0.2 1.7 1 1 0 1 1 1 0 Tetrabrachion PCNA_N PF00705.18 EEQ38006.1 - 2.3e-50 169.6 4.7 7.4e-49 164.7 2.7 2.8 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EEQ38006.1 - 2.9e-47 160.0 0.0 5.4e-47 159.1 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 EEQ38006.1 - 1.3e-06 27.7 0.7 0.00025 20.2 0.7 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EEQ38006.1 - 5.2e-06 26.1 0.3 6.3e-06 25.8 0.3 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 EEQ38006.1 - 0.00021 20.5 0.0 0.019 14.1 0.0 2.1 2 0 0 2 2 2 2 Hus1-like protein DUF229 PF02995.17 EEQ38006.1 - 0.038 12.6 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) RVT_2 PF07727.14 EEQ38006.1 - 0.15 11.7 0.2 0.71 9.5 0.1 2.0 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) MTA_R1 PF17226.2 EEQ38008.1 - 0.034 14.3 0.1 0.08 13.1 0.1 1.6 1 0 0 1 1 1 0 MTA R1 domain Sec62 PF03839.16 EEQ38009.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 RFX_DNA_binding PF02257.15 EEQ38011.1 - 1.4e-08 35.2 0.0 2.6e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain Amino_oxidase PF01593.24 EEQ38015.1 - 2.1e-56 192.1 0.0 4.7e-56 191.0 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ38015.1 - 7.5e-11 42.1 0.0 1.9e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ38015.1 - 5.5e-07 29.5 0.3 8e-06 25.7 0.4 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ38015.1 - 6.4e-06 25.6 0.0 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ38015.1 - 7.1e-05 22.2 1.2 0.0044 16.3 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ38015.1 - 0.00019 21.5 0.2 0.06 13.3 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EEQ38015.1 - 0.00039 19.2 0.1 0.04 12.6 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EEQ38015.1 - 0.00061 19.0 0.2 0.00086 18.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EEQ38015.1 - 0.0035 16.8 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 EEQ38015.1 - 0.0037 16.4 0.3 0.65 9.0 0.2 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 EEQ38015.1 - 0.0043 16.3 0.1 0.0069 15.7 0.1 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EEQ38015.1 - 0.079 12.0 0.3 0.31 10.1 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EEQ38015.1 - 0.12 11.6 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Methyltransf_11 PF08241.12 EEQ38016.1 - 1.2e-24 86.8 0.0 2.6e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ38016.1 - 3.9e-22 78.7 0.0 5.3e-22 78.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ38016.1 - 2.4e-19 69.8 0.0 5.6e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ38016.1 - 2.4e-17 63.3 0.0 5.8e-17 62.0 0.0 1.5 1 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ38016.1 - 1.4e-12 47.5 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EEQ38016.1 - 2.8e-12 47.2 0.0 6.3e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EEQ38016.1 - 1.2e-07 31.5 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 EEQ38016.1 - 2.2e-07 30.1 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.12 EEQ38016.1 - 7.2e-06 25.7 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 EEQ38016.1 - 0.0001 21.5 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 EEQ38016.1 - 0.00033 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 EEQ38016.1 - 0.0025 16.9 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 EEQ38016.1 - 0.0032 16.1 0.0 0.0049 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 EEQ38016.1 - 0.0072 15.9 0.0 0.024 14.2 0.0 1.8 2 1 1 3 3 3 1 Methyltransferase small domain CMAS PF02353.20 EEQ38016.1 - 0.08 12.2 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EEQ38016.1 - 0.15 12.0 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2458 PF10454.9 EEQ38017.1 - 1.9e-07 30.9 4.2 1.9e-07 30.9 4.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2458) DUF2179 PF10035.9 EEQ38017.1 - 0.033 13.9 0.5 0.086 12.6 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2179) CppA_N PF14506.6 EEQ38017.1 - 0.2 11.8 4.3 0.21 11.7 0.2 2.3 1 1 0 2 2 2 0 CppA N-terminal V_ATPase_I PF01496.19 EEQ38017.1 - 2.9 5.7 10.9 0.55 8.1 7.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family IZUMO PF15005.6 EEQ38017.1 - 2.9 8.4 8.4 0.6 10.6 4.3 1.8 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Piezo_RRas_bdg PF12166.8 EEQ38017.1 - 10 5.3 9.3 44 3.2 9.3 1.8 1 1 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Adap_comp_sub PF00928.21 EEQ38018.1 - 5.7e-87 291.4 0.6 8.5e-87 290.9 0.6 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEQ38018.1 - 5.2e-07 29.7 5.0 1.3e-06 28.4 4.1 1.9 1 1 1 2 2 2 1 Clathrin adaptor complex small chain muHD PF10291.9 EEQ38018.1 - 0.0031 17.0 0.3 0.0061 16.0 0.0 1.6 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Tox-ART-HYE1 PF15634.6 EEQ38018.1 - 0.024 14.0 0.2 0.15 11.4 0.3 1.9 2 0 0 2 2 2 0 HYE1 signature containing ADP-ribosyltransferase Glyco_hydro_72 PF03198.14 EEQ38019.1 - 1.2e-134 448.5 2.2 1.6e-134 448.1 2.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Apt1 PF10351.9 EEQ38019.1 - 5.3 5.8 7.1 7.7 5.2 7.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain PCI PF01399.27 EEQ38021.1 - 1.1e-16 61.2 0.7 1.1e-16 61.2 0.7 2.2 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EEQ38021.1 - 4.1e-14 52.4 1.6 4.1e-14 52.4 1.6 2.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain HisG PF01634.18 EEQ38022.1 - 6.8e-51 172.4 0.0 9.8e-51 171.9 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EEQ38022.1 - 5.2e-28 97.0 0.1 1e-27 96.1 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EEQ38022.1 - 0.0033 17.4 0.1 0.0075 16.2 0.1 1.5 1 1 0 1 1 1 1 NMT1/THI5 like Prenyltransf PF01255.19 EEQ38023.1 - 9.4e-74 247.7 0.0 1.1e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Pkinase PF00069.25 EEQ38024.1 - 1.8e-72 243.9 0.0 3.9e-72 242.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38024.1 - 3e-36 125.1 0.0 4.8e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EEQ38024.1 - 2.5e-33 114.3 0.3 5.6e-33 113.1 0.3 1.6 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 EEQ38024.1 - 0.00016 21.1 0.0 0.00033 20.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ38024.1 - 0.018 15.0 0.1 0.16 11.9 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF501 PF04417.12 EEQ38024.1 - 0.23 11.3 1.7 0.86 9.4 1.7 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Cyclin_C_2 PF16899.5 EEQ38025.1 - 9.6e-30 103.0 0.1 1.5e-28 99.2 0.0 2.3 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 EEQ38025.1 - 1e-08 34.9 0.6 1.9e-08 34.1 0.6 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 EEQ38025.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat LCD1 PF09798.9 EEQ38026.1 - 1.1e-164 549.3 0.0 1.3e-164 549.1 0.0 1.0 1 0 0 1 1 1 1 DNA damage checkpoint protein HALZ PF02183.18 EEQ38026.1 - 0.00063 19.9 1.7 0.0021 18.3 0.2 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper DUF2205 PF10224.9 EEQ38026.1 - 0.028 14.4 0.9 0.086 12.8 0.9 1.9 1 1 0 1 1 1 0 Short coiled-coil protein DUF4600 PF15372.6 EEQ38026.1 - 0.029 14.8 0.5 0.062 13.7 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) U3_assoc_6 PF08640.11 EEQ38026.1 - 0.067 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 HAP1_N PF04849.13 EEQ38026.1 - 0.074 12.2 1.0 0.16 11.2 1.0 1.5 1 0 0 1 1 1 0 HAP1 N-terminal conserved region APG6_N PF17675.1 EEQ38026.1 - 0.097 13.2 3.9 0.18 12.3 3.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Syntaxin-6_N PF09177.11 EEQ38026.1 - 0.12 12.9 1.1 0.28 11.8 1.1 1.6 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Jnk-SapK_ap_N PF09744.9 EEQ38026.1 - 0.14 12.4 3.4 0.27 11.5 3.4 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 EEQ38026.1 - 0.27 8.7 3.1 0.39 8.2 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GCN5L1 PF06320.13 EEQ38026.1 - 0.34 11.1 2.9 0.63 10.2 2.9 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) DUF4140 PF13600.6 EEQ38026.1 - 0.99 9.9 5.5 23 5.5 5.5 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TMF_TATA_bd PF12325.8 EEQ38026.1 - 1 9.6 3.6 2.7 8.3 0.4 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Cep57_CLD_2 PF14197.6 EEQ38026.1 - 2.3 8.4 6.7 6.7 6.9 6.7 1.9 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 EEQ38026.1 - 4.6 7.1 6.4 11 5.9 0.5 2.7 1 1 1 2 2 2 0 Septum formation initiator EMG1 PF03587.14 EEQ38027.1 - 9.5e-79 263.6 0.0 1.4e-78 263.0 0.0 1.3 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Hydin_ADK PF17213.3 EEQ38027.1 - 1.6 9.0 6.9 2.3 8.4 6.9 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain FHA PF00498.26 EEQ38028.1 - 0.00051 20.3 0.1 0.0011 19.2 0.1 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EEQ38028.1 - 0.028 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain OGG_N PF07934.12 EEQ38029.1 - 2.1e-29 102.1 0.5 5.6e-29 100.7 0.0 2.0 2 1 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EEQ38029.1 - 1.2e-15 57.9 0.0 2.8e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EEQ38029.1 - 0.015 15.1 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF1673 PF07895.11 EEQ38032.1 - 0.044 13.5 0.1 0.075 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Ly49 PF08391.10 EEQ38032.1 - 0.22 11.9 2.9 0.25 11.7 1.9 1.6 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region ADH_zinc_N PF00107.26 EEQ38033.1 - 2e-20 73.1 0.0 2.7e-19 69.5 0.0 1.9 1 1 1 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ38033.1 - 4.3e-08 34.3 0.0 5.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEQ38033.1 - 0.017 14.4 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MgsA_C PF12002.8 EEQ38035.1 - 8.7e-57 191.7 0.2 2.4e-56 190.3 0.0 1.8 2 0 0 2 2 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EEQ38035.1 - 3.1e-21 75.5 0.0 1.3e-20 73.5 0.0 2.1 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EEQ38035.1 - 2.8e-17 63.4 0.0 6.2e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ38035.1 - 2.5e-14 53.3 0.0 5.3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEQ38035.1 - 5.3e-08 33.0 0.0 3.9e-07 30.2 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EEQ38035.1 - 6e-08 32.8 0.1 1.8e-07 31.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain Sigma54_activat PF00158.26 EEQ38035.1 - 1.2e-07 31.6 0.0 9.2e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.14 EEQ38035.1 - 1.7e-06 28.2 0.0 5.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EEQ38035.1 - 0.0001 21.8 0.1 0.041 13.2 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.6 EEQ38035.1 - 0.0007 19.7 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EEQ38035.1 - 0.0017 18.8 7.2 0.058 13.8 0.0 3.2 2 2 1 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 EEQ38035.1 - 0.004 17.7 1.3 0.049 14.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 EEQ38035.1 - 0.0052 16.6 0.0 0.032 14.1 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ38035.1 - 0.0068 16.7 0.2 0.5 10.6 0.2 2.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ38035.1 - 0.0086 16.3 0.0 0.24 11.6 0.0 3.1 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EEQ38035.1 - 0.03 14.1 2.9 0.034 13.9 0.0 2.4 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 EEQ38035.1 - 0.062 13.5 0.2 0.76 10.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_8 PF12780.7 EEQ38035.1 - 0.075 12.3 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 zf-C2HC_2 PF13913.6 EEQ38035.1 - 0.079 12.9 1.9 0.17 11.8 1.9 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type MCM PF00493.23 EEQ38035.1 - 0.085 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 MCM P-loop domain IstB_IS21 PF01695.17 EEQ38035.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TFIIA PF03153.13 EEQ38035.1 - 3.5 7.5 25.3 2.7 7.9 15.5 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Baculo_PEP_C PF04513.12 EEQ38036.1 - 0.0023 18.0 1.9 0.0023 18.0 1.9 3.9 4 0 0 4 4 4 1 Baculovirus polyhedron envelope protein, PEP, C terminus IL31 PF15209.6 EEQ38036.1 - 0.088 12.6 0.0 0.5 10.1 0.0 2.3 2 1 0 2 2 2 0 Interleukin 31 UPF0114 PF03350.16 EEQ38036.1 - 4.2 7.6 7.4 0.97 9.7 0.4 3.0 3 0 0 3 3 3 0 Uncharacterized protein family, UPF0114 Rad60-SLD PF11976.8 EEQ38037.1 - 1.5e-18 66.3 0.0 1.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EEQ38037.1 - 8e-10 38.3 0.0 9.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Vasohibin PF14822.6 EEQ38037.1 - 0.12 11.5 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 Vasohibin SRP9-21 PF05486.12 EEQ38037.1 - 0.16 12.3 0.1 0.2 12.1 0.1 1.1 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) PSP1 PF04468.12 EEQ38039.1 - 3.4e-27 94.5 0.5 3.4e-27 94.5 0.5 2.1 2 1 0 2 2 2 1 PSP1 C-terminal conserved region Zip PF02535.22 EEQ38039.1 - 0.0066 15.7 4.8 0.008 15.4 4.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter PRP1_N PF06424.12 EEQ38039.1 - 0.023 15.1 6.1 0.037 14.4 6.1 1.3 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal TFIIA PF03153.13 EEQ38039.1 - 0.024 14.7 21.6 0.034 14.1 21.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 EEQ38039.1 - 0.32 10.5 12.9 0.5 9.9 12.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EEQ38039.1 - 0.8 7.5 9.4 1 7.2 9.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Otopetrin PF03189.13 EEQ38039.1 - 4 6.2 8.0 6.1 5.5 8.0 1.2 1 0 0 1 1 1 0 Otopetrin Presenilin PF01080.17 EEQ38039.1 - 6.2 5.5 20.5 9 4.9 20.5 1.1 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 EEQ38039.1 - 8 3.4 17.7 11 3.0 17.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 EEQ38039.1 - 9.9 6.4 12.7 18 5.6 12.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PAP2 PF01569.21 EEQ38040.1 - 4.8e-24 84.7 3.6 4.8e-24 84.7 3.6 2.4 2 1 1 3 3 3 1 PAP2 superfamily SH3_9 PF14604.6 EEQ38042.1 - 1.9e-09 37.2 0.0 3.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ38042.1 - 1.5e-06 27.7 0.0 2.4e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ38042.1 - 1.4e-05 24.7 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF4448 PF14610.6 EEQ38042.1 - 0.0004 20.2 0.2 0.00062 19.6 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 EEQ38042.1 - 0.011 15.1 0.5 0.024 14.0 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM154 PF15102.6 EEQ38042.1 - 0.3 11.0 2.2 0.3 11.0 0.9 1.6 1 1 0 1 1 1 0 TMEM154 protein family PH PF00169.29 EEQ38043.1 - 6.4e-08 33.1 0.4 4.3e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 PH domain Amidohydro_1 PF01979.20 EEQ38044.1 - 2.4e-69 234.2 0.0 2.9e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ38044.1 - 8.9e-10 38.6 0.0 1.2e-06 28.2 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family CFEM PF05730.11 EEQ38046.1 - 1.1e-08 35.1 13.0 2.5e-08 33.9 13.0 1.7 1 0 0 1 1 1 1 CFEM domain RR_TM4-6 PF06459.12 EEQ38046.1 - 0.76 9.6 5.5 0.95 9.2 5.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RIFIN PF02009.16 EEQ38046.1 - 4.3 7.1 4.6 5.9 6.7 4.6 1.3 1 0 0 1 1 1 0 Rifin Presenilin PF01080.17 EEQ38046.1 - 4.4 6.0 10.0 5.4 5.7 10.0 1.2 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 EEQ38046.1 - 8.1 5.5 29.4 9.9 5.2 29.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Plasmodium_Vir PF05795.11 EEQ38046.1 - 8.9 5.6 8.2 9.8 5.5 8.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.7 EEQ38046.1 - 9.3 4.2 13.5 10 4.1 13.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein HTH_28 PF13518.6 EEQ38047.1 - 0.33 11.1 4.6 0.15 12.2 1.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain PWWP PF00855.17 EEQ38049.1 - 4.5 7.7 5.6 0.61 10.5 0.3 2.0 2 0 0 2 2 2 0 PWWP domain Utp14 PF04615.13 EEQ38050.1 - 0.0071 15.0 24.6 0.0093 14.6 24.6 1.1 1 0 0 1 1 1 1 Utp14 protein RskA PF10099.9 EEQ38052.1 - 0.019 15.3 1.9 0.019 15.3 1.9 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA EPL1 PF10513.9 EEQ38052.1 - 1 9.7 15.5 1.3 9.4 6.5 3.0 2 1 0 2 2 2 0 Enhancer of polycomb-like Ferric_reduct PF01794.19 EEQ38053.1 - 2e-18 66.7 16.6 2e-18 66.7 16.6 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ38053.1 - 4.8e-15 56.0 0.0 8.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ38053.1 - 2.1e-14 53.6 0.0 3.5e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.6 EEQ38053.1 - 7.5 7.2 22.1 1.3 9.6 5.1 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Rogdi_lz PF10259.9 EEQ38054.1 - 9.4e-61 205.6 0.0 1.1e-60 205.4 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Peptidase_M16_M PF16187.5 EEQ38055.1 - 6.5e-81 271.7 2.6 6.5e-81 271.7 2.6 1.9 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EEQ38055.1 - 2.4e-43 147.7 0.3 7.2e-43 146.1 0.3 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEQ38055.1 - 5e-25 88.6 1.6 6.7e-13 49.0 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain ABC2_membrane PF01061.24 EEQ38056.1 - 5.4e-83 277.5 54.9 1.2e-42 145.7 20.7 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EEQ38056.1 - 8e-41 139.8 0.0 7.7e-19 68.6 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 EEQ38056.1 - 2.1e-34 117.3 2.7 2e-29 101.3 0.2 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EEQ38056.1 - 1.1e-19 70.8 0.0 3.5e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EEQ38056.1 - 3e-07 30.5 0.1 5e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EEQ38056.1 - 1.6e-06 27.9 0.1 6e-05 22.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EEQ38056.1 - 2.5e-06 28.2 0.9 0.12 12.9 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EEQ38056.1 - 2.1e-05 25.0 0.1 0.00051 20.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EEQ38056.1 - 0.00014 21.5 0.2 0.088 12.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EEQ38056.1 - 0.001 18.6 0.0 0.62 9.4 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ38056.1 - 0.0013 18.6 0.0 1.9 8.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EEQ38056.1 - 0.0026 17.5 0.1 0.24 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ38056.1 - 0.0026 18.0 0.4 0.16 12.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EEQ38056.1 - 0.004 16.3 10.7 0.004 16.3 10.7 3.3 3 1 0 3 3 3 2 ABC-2 family transporter protein MMR_HSR1 PF01926.23 EEQ38056.1 - 0.0069 16.5 0.2 0.62 10.2 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EEQ38056.1 - 0.0076 16.2 1.2 1 9.2 0.2 2.9 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 EEQ38056.1 - 0.045 14.3 0.1 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EEQ38056.1 - 0.073 12.7 3.7 1.1 8.8 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 EEQ38056.1 - 0.13 12.4 2.6 0.22 11.7 0.2 2.2 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EEQ38056.1 - 0.17 10.6 0.6 1.5 7.6 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_17 PF13207.6 EEQ38056.1 - 0.26 11.7 0.6 50 4.3 0.1 3.1 2 1 0 2 2 2 0 AAA domain Sec1 PF00995.23 EEQ38057.1 - 9e-103 345.5 3.6 1e-102 345.3 3.6 1.0 1 0 0 1 1 1 1 Sec1 family Syntaxin-18_N PF10496.9 EEQ38057.1 - 0.095 13.0 0.8 0.31 11.3 0.8 1.9 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus PHD PF00628.29 EEQ38058.1 - 5.7e-09 35.7 3.6 5.7e-09 35.7 3.6 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EEQ38058.1 - 0.016 14.7 4.0 0.026 14.1 4.0 1.3 1 0 0 1 1 1 0 PHD-finger DUF678 PF05077.12 EEQ38058.1 - 0.19 11.9 1.0 0.55 10.4 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF678) CT_A_B PF02626.15 EEQ38058.1 - 0.26 10.9 0.8 16 5.0 0.5 2.2 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain A and B GTA_holin_3TM PF11351.8 EEQ38058.1 - 3.3 8.3 6.5 4.5 7.8 4.5 2.1 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release ALO PF04030.14 EEQ38059.1 - 9.6e-102 340.2 0.3 1.5e-101 339.6 0.1 1.4 2 0 0 2 2 2 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EEQ38059.1 - 1.7e-23 82.9 0.0 2.6e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain MciZ PF13072.6 EEQ38059.1 - 0.032 14.1 0.2 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ Utp14 PF04615.13 EEQ38060.1 - 4.4e-177 591.0 81.0 4.4e-177 591.0 81.0 2.2 1 1 1 2 2 2 1 Utp14 protein DUF2207 PF09972.9 EEQ38061.1 - 0.048 12.4 0.3 0.051 12.3 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ETRAMP PF09716.10 EEQ38061.1 - 0.09 12.9 0.6 0.14 12.2 0.6 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Cortexin PF11057.8 EEQ38063.1 - 0.05 13.5 0.6 0.19 11.6 0.3 2.0 2 0 0 2 2 2 0 Cortexin of kidney REC104 PF17378.2 EEQ38063.1 - 0.095 12.5 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC104 UPF0160 PF03690.13 EEQ38064.1 - 0.043 13.5 0.2 0.05 13.2 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0160) Presenilin PF01080.17 EEQ38068.1 - 0.14 10.9 0.1 0.18 10.5 0.1 1.1 1 0 0 1 1 1 0 Presenilin Proteasome PF00227.26 EEQ38070.1 - 9.8e-57 191.5 0.0 1.2e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ38070.1 - 0.007 16.0 0.3 0.025 14.2 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature ABC_tran PF00005.27 EEQ38071.1 - 1.2e-50 171.6 0.2 1.3e-26 93.7 0.0 5.1 4 3 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 EEQ38071.1 - 2.4e-15 57.1 0.9 0.0005 20.0 0.3 4.8 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ38071.1 - 1.5e-11 44.2 0.0 0.012 15.1 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EEQ38071.1 - 1.5e-08 34.4 0.1 3.4e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.6 EEQ38071.1 - 5.9e-08 32.3 0.4 0.0047 16.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EEQ38071.1 - 1.5e-07 31.5 0.0 0.003 17.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 EEQ38071.1 - 2.3e-07 31.5 10.7 0.00082 19.9 0.0 4.1 5 0 0 5 5 4 2 AAA domain RsgA_GTPase PF03193.16 EEQ38071.1 - 8.5e-07 29.0 0.1 0.0087 16.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EEQ38071.1 - 1.9e-05 24.5 0.7 0.074 12.7 0.0 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EEQ38071.1 - 4.5e-05 23.7 0.0 0.3 11.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 EEQ38071.1 - 6.4e-05 22.1 0.4 0.19 10.7 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EEQ38071.1 - 6.6e-05 23.5 0.3 0.21 12.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 EEQ38071.1 - 0.00022 21.5 0.0 0.18 12.1 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_16 PF13191.6 EEQ38071.1 - 0.0007 20.0 0.2 0.18 12.2 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EEQ38071.1 - 0.00085 19.5 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EEQ38071.1 - 0.0011 19.3 0.0 1.3 9.4 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_27 PF13514.6 EEQ38071.1 - 0.0012 18.5 0.0 1.4 8.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EEQ38071.1 - 0.0027 18.1 0.1 2.8 8.4 0.0 3.7 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EEQ38071.1 - 0.003 17.3 0.0 1.4 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EEQ38071.1 - 0.0051 16.9 9.0 0.09 12.9 0.1 4.8 4 1 1 5 5 5 1 Helicase HerA, central domain AAA_13 PF13166.6 EEQ38071.1 - 0.0083 14.8 0.0 1.5 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EEQ38071.1 - 0.01 15.9 1.6 0.3 11.1 0.0 3.3 3 0 0 3 3 3 0 Dynamin family Zeta_toxin PF06414.12 EEQ38071.1 - 0.012 14.9 0.1 3.4 6.9 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.12 EEQ38071.1 - 0.015 15.2 0.1 6.9 6.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain PPP5 PF08321.12 EEQ38071.1 - 0.016 15.5 0.2 0.043 14.1 0.2 1.8 1 0 0 1 1 1 0 PPP5 TPR repeat region Rad17 PF03215.15 EEQ38071.1 - 0.017 15.0 0.1 0.65 9.9 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 EEQ38071.1 - 0.019 14.7 0.1 1 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EEQ38071.1 - 0.021 14.0 0.6 2.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.22 EEQ38071.1 - 0.026 13.7 0.0 4.1 6.5 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EEQ38071.1 - 0.035 14.0 0.1 2.7 7.9 0.1 2.7 3 0 0 3 3 2 0 NTPase ABC_ATPase PF09818.9 EEQ38071.1 - 0.035 12.9 0.2 0.94 8.2 0.0 2.8 2 1 0 2 2 2 0 Predicted ATPase of the ABC class TsaE PF02367.17 EEQ38071.1 - 0.042 13.9 0.1 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 EEQ38071.1 - 0.056 13.7 0.0 5.6 7.2 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EEQ38071.1 - 0.076 13.0 0.0 2.1 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain MukB PF04310.12 EEQ38071.1 - 0.1 12.4 0.1 14 5.4 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal cobW PF02492.19 EEQ38071.1 - 0.12 12.0 0.9 9.7 5.7 0.0 3.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 EEQ38071.1 - 0.12 12.2 0.0 25 4.7 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 EEQ38071.1 - 0.14 11.8 0.3 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_7 PF12775.7 EEQ38071.1 - 0.18 11.3 0.2 4.1 6.9 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran_Xtn PF12848.7 EEQ38071.1 - 0.8 9.8 5.9 0.56 10.3 0.4 2.9 2 0 0 2 2 2 0 ABC transporter DUF3584 PF12128.8 EEQ38071.1 - 3.3 5.1 10.0 1.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Striatin PF08232.12 EEQ38073.1 - 1.7e-15 58.0 17.6 5e-15 56.4 17.6 1.8 1 1 0 1 1 1 1 Striatin family DUF3450 PF11932.8 EEQ38073.1 - 0.069 12.4 6.4 0.14 11.4 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Macoilin PF09726.9 EEQ38073.1 - 0.41 9.2 13.8 0.59 8.6 13.8 1.1 1 0 0 1 1 1 0 Macoilin family RR_TM4-6 PF06459.12 EEQ38073.1 - 0.52 10.1 13.7 0.73 9.6 13.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3807 PF12720.7 EEQ38073.1 - 1.5 9.1 20.8 2.6 8.3 20.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CRT10 PF08728.10 EEQ38073.1 - 1.6 6.8 6.3 2.2 6.3 6.3 1.1 1 0 0 1 1 1 0 CRT10 DDHD PF02862.17 EEQ38073.1 - 1.8 8.7 8.0 3.3 7.8 8.0 1.5 1 0 0 1 1 1 0 DDHD domain Zip PF02535.22 EEQ38073.1 - 4.8 6.3 7.4 7.1 5.7 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 EEQ38073.1 - 6 5.6 9.3 8.5 5.1 9.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Vfa1 PF08432.10 EEQ38073.1 - 7.2 6.9 19.9 14 5.9 19.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF809 PF05663.11 EEQ38073.1 - 8 6.6 9.3 15 5.8 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Polysacc_synt_4 PF04669.13 EEQ38074.1 - 1.1e-18 67.5 1.2 9.5e-17 61.2 1.2 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Birna_VP5 PF03042.14 EEQ38074.1 - 0.015 15.4 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Birnavirus VP5 protein Amino_oxidase PF01593.24 EEQ38075.1 - 3.7e-57 194.6 0.8 3.6e-37 128.7 0.1 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ38075.1 - 8.5e-11 41.9 0.2 2.1e-10 40.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EEQ38075.1 - 1.7e-05 24.6 6.8 7.6e-05 22.4 6.8 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ38075.1 - 0.00043 19.6 0.0 0.015 14.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ38075.1 - 0.00078 19.5 0.3 0.022 14.8 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EEQ38075.1 - 0.00096 18.5 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family MCRA PF06100.11 EEQ38075.1 - 0.0075 15.1 0.1 0.013 14.3 0.1 1.4 1 0 0 1 1 1 1 MCRA family FAD_binding_2 PF00890.24 EEQ38075.1 - 0.008 15.3 1.4 0.016 14.3 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EEQ38075.1 - 0.01 15.1 0.2 0.019 14.2 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EEQ38075.1 - 0.034 13.4 0.1 0.063 12.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EEQ38075.1 - 0.092 11.4 0.6 0.14 10.8 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EEQ38075.1 - 0.14 11.4 0.8 0.3 10.3 0.8 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zip PF02535.22 EEQ38075.1 - 2 7.6 9.9 0.21 10.8 0.3 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter UQ_con PF00179.26 EEQ38076.1 - 2e-50 170.1 0.0 2.2e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SNase PF00565.17 EEQ38077.1 - 4.2e-23 81.9 0.8 1.3e-09 38.5 0.1 3.8 3 0 0 3 3 3 3 Staphylococcal nuclease homologue TUDOR PF00567.24 EEQ38077.1 - 1.9e-14 53.7 0.0 3.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Tudor domain PPC PF04151.15 EEQ38077.1 - 0.00027 21.9 0.3 0.38 11.9 0.0 3.5 3 0 0 3 3 3 1 Bacterial pre-peptidase C-terminal domain Tudor_2 PF18104.1 EEQ38077.1 - 0.1 12.3 0.2 0.68 9.7 0.1 2.3 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain Pho88 PF10032.9 EEQ38078.1 - 1.6e-81 271.9 0.6 1.8e-81 271.7 0.6 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF3034 PF11231.8 EEQ38079.1 - 0.037 13.6 0.1 0.09 12.3 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3034) SET PF00856.28 EEQ38080.1 - 1.1e-08 35.6 0.0 3.3e-08 34.1 0.0 1.7 2 0 0 2 2 2 1 SET domain SCO1-SenC PF02630.14 EEQ38081.1 - 4.4e-44 149.7 0.0 6e-44 149.2 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EEQ38081.1 - 0.00069 19.5 0.1 0.0016 18.3 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Transp_cyt_pur PF02133.15 EEQ38082.1 - 1.2e-14 53.9 36.0 2.5e-14 52.9 36.0 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PhyH PF05721.13 EEQ38083.1 - 5.6e-47 160.7 0.1 6.6e-47 160.5 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EEQ38083.1 - 0.028 14.8 0.0 0.063 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase FHA PF00498.26 EEQ38084.1 - 1.7e-13 50.7 0.0 3.1e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EEQ38084.1 - 0.0056 17.0 0.0 0.016 15.5 0.0 1.8 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Spt20 PF12090.8 EEQ38085.1 - 1.2e-54 185.4 0.0 1.2e-54 185.4 0.0 8.6 4 2 3 7 7 7 1 Spt20 family DCP1 PF06058.13 EEQ38086.1 - 9.3e-26 90.1 0.0 1.4e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Redoxin PF08534.10 EEQ38087.1 - 3.7e-37 127.3 0.0 4.4e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EEQ38087.1 - 2.1e-10 40.6 0.0 2.7e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family RF-1 PF00472.20 EEQ38088.1 - 1.5e-23 83.0 0.6 1.8e-23 82.7 0.6 1.1 1 0 0 1 1 1 1 RF-1 domain efThoc1 PF11957.8 EEQ38089.1 - 9.1e-80 268.7 21.5 1.4e-79 268.0 21.5 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor FAM60A PF15396.6 EEQ38089.1 - 2.5 8.0 10.0 8.1 6.4 10.0 1.9 1 0 0 1 1 1 0 Protein Family FAM60A Rif1_N PF12231.8 EEQ38090.1 - 5.1e-35 121.2 0.1 1.6e-34 119.5 0.1 1.9 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.25 EEQ38091.1 - 1.2e-24 87.1 0.0 5.3e-24 85.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38091.1 - 1.8e-11 43.8 0.0 2.3e-10 40.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase UPF0547 PF10571.9 EEQ38091.1 - 0.089 12.9 1.0 0.21 11.7 1.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 Pkinase_fungal PF17667.1 EEQ38091.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EEQ38091.1 - 0.13 12.2 0.2 0.29 11.0 0.2 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family zinc_ribbon_9 PF14369.6 EEQ38091.1 - 5.6 7.3 6.8 1.1 9.5 0.2 2.8 3 0 0 3 3 3 0 zinc-ribbon PLA2_B PF01735.18 EEQ38092.1 - 3.9e-138 460.9 0.2 7.2e-138 460.1 0.2 1.4 1 1 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EEQ38092.1 - 0.61 10.4 5.7 0.26 11.6 2.5 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain NTP_transf_2 PF01909.23 EEQ38093.1 - 3.5e-16 59.3 0.0 3.8e-14 52.7 0.0 2.9 2 1 1 3 3 3 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EEQ38093.1 - 1e-12 48.1 0.0 2.5e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EEQ38093.1 - 4.5e-05 23.5 0.3 0.00038 20.5 0.0 2.3 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase tRNA_NucTransf2 PF09249.11 EEQ38093.1 - 0.12 12.6 0.4 3.2 8.0 0.1 2.7 2 1 0 2 2 2 0 tRNA nucleotidyltransferase, second domain Ras PF00071.22 EEQ38094.1 - 4.9e-46 156.3 0.0 5.7e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ38094.1 - 4.3e-34 117.3 0.0 6.2e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ38094.1 - 1.4e-11 44.2 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EEQ38094.1 - 3e-06 27.2 0.0 0.023 14.6 0.0 2.1 1 1 1 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EEQ38094.1 - 4.3e-06 26.2 0.0 6.3e-06 25.7 0.0 1.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ38094.1 - 3.2e-05 24.0 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ38094.1 - 6.2e-05 22.6 0.0 0.016 14.7 0.0 2.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEQ38094.1 - 0.00093 18.7 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EEQ38094.1 - 0.0058 17.0 0.0 0.0076 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EEQ38094.1 - 0.0097 15.3 0.0 0.1 12.0 0.0 2.2 2 1 0 2 2 2 1 Bacterial TniB protein FeoB_N PF02421.18 EEQ38094.1 - 0.022 14.3 0.0 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B DLIC PF05783.11 EEQ38094.1 - 0.022 13.6 0.0 0.4 9.5 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_24 PF13479.6 EEQ38094.1 - 0.093 12.4 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EEQ38094.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 NTPase MMR_HSR1_Xtn PF16897.5 EEQ38094.1 - 0.14 12.1 0.0 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain SecY PF00344.20 EEQ38095.1 - 1.2e-42 146.3 13.9 1.6e-42 145.9 13.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EEQ38095.1 - 0.0077 16.1 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p MFS_1 PF07690.16 EEQ38096.1 - 4e-42 144.4 53.5 2.8e-40 138.3 54.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ38096.1 - 2.1e-17 62.8 26.5 2.1e-17 62.8 26.5 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ38096.1 - 1.6e-08 33.8 21.1 1.6e-08 33.8 21.1 3.8 4 0 0 4 4 4 1 Sugar (and other) transporter DMRL_synthase PF00885.19 EEQ38097.1 - 2.6e-42 144.0 0.0 2.9e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase zf-CHY PF05495.12 EEQ38099.1 - 6.6e-13 49.0 13.0 9.7e-13 48.4 13.0 1.4 1 1 0 1 1 1 1 CHY zinc finger Zn_ribbon_recom PF13408.6 EEQ38099.1 - 0.026 15.0 2.0 0.026 15.0 2.0 2.2 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Evr1_Alr PF04777.13 EEQ38099.1 - 0.64 10.5 5.0 1.9 9.0 2.2 2.1 1 1 1 2 2 2 0 Erv1 / Alr family DUF1815 PF08844.10 EEQ38099.1 - 0.79 9.7 3.4 3.4 7.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) Jas PF16135.5 EEQ38099.1 - 7.8 6.8 10.9 0.085 13.1 1.8 2.2 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling Cyclin_N PF00134.23 EEQ38100.1 - 5.9e-45 152.1 0.1 1.2e-44 151.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEQ38100.1 - 5.4e-36 123.3 0.1 1.3e-35 122.1 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain LAT PF15234.6 EEQ38100.1 - 0.077 12.7 4.1 0.12 12.1 4.1 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells DNA_pol_phi PF04931.13 EEQ38100.1 - 0.95 7.5 7.7 1.3 7.0 7.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi MAM33 PF02330.16 EEQ38101.1 - 1.2e-38 133.2 8.7 1.5e-38 132.9 8.7 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein LytR_C PF13399.6 EEQ38101.1 - 0.06 14.3 0.3 0.25 12.3 0.1 2.3 2 1 1 3 3 3 0 LytR cell envelope-related transcriptional attenuator RRM_1 PF00076.22 EEQ38102.1 - 2e-68 226.1 2.7 1.1e-17 63.5 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ38102.1 - 1.7e-10 40.6 0.3 0.00064 19.5 0.0 4.8 4 1 1 5 5 5 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EEQ38102.1 - 8.1e-10 38.4 0.0 0.00036 20.1 0.0 4.3 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EEQ38102.1 - 0.00024 21.1 12.4 0.098 12.7 0.1 5.0 5 0 0 5 5 5 2 RNA binding motif RRM_7 PF16367.5 EEQ38102.1 - 0.00069 19.7 0.1 4.8 7.4 0.0 4.1 4 0 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EEQ38102.1 - 0.0013 18.7 2.5 17 5.5 0.0 4.5 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EEQ38102.1 - 0.0029 17.6 0.0 4.8 7.3 0.0 4.2 4 0 0 4 4 4 1 Limkain b1 SET_assoc PF11767.8 EEQ38102.1 - 0.0078 15.8 0.0 5.2 6.8 0.0 3.4 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated Acyltransf_C PF16076.5 EEQ38104.1 - 4.8e-05 23.4 0.0 9.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus AAA_23 PF13476.6 EEQ38105.1 - 6.8e-26 92.0 14.3 6.8e-26 92.0 14.3 7.6 2 2 0 2 2 1 1 AAA domain AAA_15 PF13175.6 EEQ38105.1 - 7.9e-10 39.0 30.5 5.7e-05 23.0 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EEQ38105.1 - 1.1e-08 35.3 0.0 0.0021 17.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EEQ38105.1 - 9.7e-06 25.7 0.0 4.2e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 EEQ38105.1 - 4.2e-05 22.4 92.0 0.0036 16.0 33.2 6.6 3 1 2 6 6 6 3 AAA domain Rad50_zn_hook PF04423.14 EEQ38105.1 - 0.00027 20.7 0.4 0.00027 20.7 0.4 4.6 3 0 0 3 3 2 1 Rad50 zinc hook motif SMC_N PF02463.19 EEQ38105.1 - 0.00062 19.3 44.5 0.012 15.0 44.5 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain GAS PF13851.6 EEQ38105.1 - 0.0056 16.1 2.7 0.0056 16.1 2.7 8.5 3 2 4 8 8 7 3 Growth-arrest specific micro-tubule binding AAA_29 PF13555.6 EEQ38105.1 - 0.0079 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 EEQ38105.1 - 0.022 13.6 123.1 0.017 14.0 4.9 8.5 4 2 4 9 9 9 0 Spc7 kinetochore protein ABC_tran PF00005.27 EEQ38105.1 - 0.034 14.6 0.0 0.034 14.6 0.0 5.8 4 1 0 5 5 4 0 ABC transporter AAA_22 PF13401.6 EEQ38105.1 - 0.15 12.4 11.6 0.27 11.5 0.0 4.6 4 1 0 4 4 4 0 AAA domain Lum_binding PF00677.17 EEQ38105.1 - 0.18 11.8 0.3 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 Lumazine binding domain ATP-synt_ab PF00006.25 EEQ38105.1 - 0.95 9.1 4.1 11 5.7 0.3 2.5 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EEQ38105.1 - 1.7 9.1 5.0 7.1 7.1 0.0 3.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Vps51 PF08700.11 EEQ38105.1 - 7 6.8 24.1 0.65 10.1 3.8 7.6 6 2 0 6 6 6 0 Vps51/Vps67 zf-C2H2 PF00096.26 EEQ38106.1 - 2.5e-20 71.7 22.7 2.6e-06 27.6 0.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ38106.1 - 8.4e-20 70.2 27.2 8.4e-09 35.5 0.7 4.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ38106.1 - 1.7e-12 47.0 20.5 0.0015 19.2 0.3 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 EEQ38106.1 - 5.1e-05 23.5 12.0 0.028 14.8 0.3 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ38106.1 - 0.0049 16.8 19.6 0.028 14.4 0.6 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EEQ38106.1 - 0.019 15.1 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 EEQ38106.1 - 0.024 14.9 0.2 0.024 14.9 0.2 3.9 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EEQ38106.1 - 0.039 14.2 6.4 0.093 13.0 2.3 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-Dof PF02701.15 EEQ38106.1 - 7.7 6.7 8.9 5.2 7.3 2.9 3.0 1 1 2 3 3 3 0 Dof domain, zinc finger SID PF11778.8 EEQ38107.1 - 2.8e-06 27.5 0.0 6.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Septation initiation CASP_C PF08172.12 EEQ38107.1 - 0.0014 18.0 2.3 0.0014 18.0 2.3 2.2 2 0 0 2 2 2 1 CASP C terminal MCC-bdg_PDZ PF10506.9 EEQ38107.1 - 0.058 13.4 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome RNA_pol_L_2 PF13656.6 EEQ38108.1 - 2.1e-33 113.9 0.1 2.7e-33 113.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EEQ38108.1 - 1.1e-14 53.5 0.0 1.5e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DEAD PF00270.29 EEQ38109.1 - 3.5e-49 167.0 0.0 7.6e-49 165.8 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ38109.1 - 1.2e-14 54.6 0.0 5.2e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ38109.1 - 1.9e-05 24.7 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ38109.1 - 0.00034 21.0 0.0 0.4 11.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EEQ38109.1 - 0.014 15.1 0.0 0.51 10.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain HLH PF00010.26 EEQ38111.1 - 3.9e-15 55.5 0.3 7.8e-15 54.6 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF5094 PF17015.5 EEQ38111.1 - 0.039 14.0 5.6 0.073 13.2 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) TMEM192 PF14802.6 EEQ38111.1 - 0.046 12.8 0.1 0.066 12.3 0.1 1.2 1 0 0 1 1 1 0 TMEM192 family Spore_II_R PF09551.10 EEQ38111.1 - 0.066 13.7 3.1 0.15 12.5 3.1 1.6 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) BIRC6 PF12356.8 EEQ38111.1 - 0.54 9.7 5.0 0.68 9.3 3.8 1.7 1 1 1 2 2 2 0 Baculoviral IAP repeat-containing protein 6 BAR_3 PF16746.5 EEQ38113.1 - 1.6e-13 50.9 0.5 4.8e-13 49.4 0.3 1.9 1 1 0 1 1 1 1 BAR domain of APPL family VASt PF16016.5 EEQ38113.1 - 3.9e-11 43.6 1.8 5.2e-11 43.2 0.7 1.8 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 EEQ38113.1 - 5.3e-08 33.3 0.8 2.4e-06 28.0 0.1 2.7 2 0 0 2 2 2 1 PH domain T3SS_needle_reg PF09025.10 EEQ38113.1 - 0.073 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator Caskin1-CID PF16600.5 EEQ38114.1 - 3.5 8.3 9.4 3.7 8.2 3.1 2.5 2 0 0 2 2 2 0 Caskin1 CASK-interaction domain PEMT PF04191.13 EEQ38115.1 - 5.6e-58 193.9 11.3 2.3e-34 118.0 1.9 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 EEQ38115.1 - 5e-07 30.2 0.0 1.3e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 SKICH domain SVM_signal PF12113.8 EEQ38115.1 - 0.031 14.2 1.7 0.21 11.5 1.7 2.5 1 0 0 1 1 1 0 SVM protein signal sequence Sec7_N PF12783.7 EEQ38116.1 - 4e-40 137.3 0.5 4e-40 137.3 0.5 6.0 5 2 3 8 8 8 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EEQ38116.1 - 1.4e-19 70.5 0.2 1.4e-19 70.5 0.2 3.9 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 EEQ38116.1 - 1e-18 67.0 3.1 3.4e-14 52.0 0.0 3.3 4 0 0 4 4 4 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 EEQ38116.1 - 4.5e-05 23.2 2.6 0.0034 17.2 0.0 4.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Questin_oxidase PF14027.6 EEQ38116.1 - 0.072 12.6 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Questin oxidase-like C5-epim_C PF06662.13 EEQ38116.1 - 0.078 12.5 0.1 0.35 10.3 0.1 2.0 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus HEAT PF02985.22 EEQ38116.1 - 0.11 12.8 0.0 0.87 10.0 0.0 2.7 1 0 0 1 1 1 0 HEAT repeat HEAT_EZ PF13513.6 EEQ38116.1 - 0.13 12.8 0.0 24 5.6 0.0 3.1 2 0 0 2 2 2 0 HEAT-like repeat DASH_Dam1 PF08653.10 EEQ38116.1 - 0.43 10.4 7.1 6.4 6.7 0.1 4.0 4 0 0 4 4 4 0 DASH complex subunit Dam1 Chitin_synth_2 PF03142.15 EEQ38117.1 - 3.8e-278 923.4 0.2 3.8e-278 923.4 0.2 1.4 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EEQ38117.1 - 3.5e-14 53.2 0.9 1.3e-13 51.3 0.9 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EEQ38117.1 - 2.9e-12 47.0 0.0 1.3e-09 38.3 0.0 2.4 1 1 1 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EEQ38117.1 - 0.00019 20.9 0.1 0.00085 18.8 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EEQ38117.1 - 0.00032 20.6 0.0 0.021 14.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Cyt-b5 PF00173.28 EEQ38117.1 - 0.027 14.6 0.1 0.11 12.6 0.0 2.1 3 0 0 3 3 3 0 Cytochrome b5-like Heme/Steroid binding domain DUF1418 PF07214.12 EEQ38117.1 - 0.3 11.0 4.8 0.88 9.5 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) FA_desaturase PF00487.24 EEQ38119.1 - 2.6e-24 86.4 23.8 3.8e-24 85.9 23.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EEQ38119.1 - 5.4e-05 23.4 0.0 0.00013 22.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) GTP_EFTU PF00009.27 EEQ38121.1 - 1.4e-63 214.0 0.1 2.4e-63 213.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EEQ38121.1 - 5.1e-36 123.1 0.2 1.8e-35 121.3 0.2 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 EEQ38121.1 - 1.1e-30 105.5 0.0 2.7e-30 104.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EEQ38121.1 - 1.4e-21 76.3 0.0 4.7e-21 74.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ38121.1 - 2.3e-13 50.3 0.2 5.6e-13 49.1 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EEQ38121.1 - 6.1e-06 26.1 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 EEQ38121.1 - 0.0064 17.0 0.0 0.12 12.9 0.0 2.7 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 EEQ38121.1 - 0.0088 16.1 0.2 0.026 14.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase tRNA-synt_1e PF01406.19 EEQ38123.1 - 6.5e-135 449.3 0.1 6.5e-135 449.3 0.1 1.8 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EEQ38123.1 - 2.5e-09 36.4 1.0 5.1e-05 22.2 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EEQ38123.1 - 0.00014 20.3 2.2 0.00049 18.5 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) CdiI_4 PF18624.1 EEQ38123.1 - 0.0012 19.3 0.4 0.0033 17.9 0.4 1.8 1 0 0 1 1 1 1 CDI immunity protein tRNA-synt_1c PF00749.21 EEQ38123.1 - 0.0027 16.7 0.5 0.091 11.6 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 EEQ38123.1 - 0.0032 16.4 0.1 0.01 14.8 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (K) SPC22 PF04573.12 EEQ38124.1 - 9.3e-58 194.5 1.8 1.2e-57 194.2 1.8 1.0 1 0 0 1 1 1 1 Signal peptidase subunit PPR_2 PF13041.6 EEQ38125.1 - 5.6e-09 36.1 1.4 0.048 13.9 0.0 5.5 7 0 0 7 7 7 2 PPR repeat family TPR_14 PF13428.6 EEQ38125.1 - 0.0058 17.3 0.1 93 4.3 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EEQ38125.1 - 0.0065 16.6 7.5 6.8 7.2 0.0 6.2 7 0 0 7 7 7 1 PPR repeat DUF5623 PF18536.1 EEQ38125.1 - 0.023 15.0 0.1 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) Phyto_Pns9_10 PF05878.11 EEQ38125.1 - 0.039 13.1 4.0 0.026 13.7 1.7 1.8 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 TPR_19 PF14559.6 EEQ38125.1 - 0.091 13.3 0.2 37 4.9 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Yip1 PF04893.17 EEQ38126.1 - 2.9e-14 53.1 7.1 4.7e-14 52.5 7.1 1.3 1 0 0 1 1 1 1 Yip1 domain Sugar_tr PF00083.24 EEQ38127.1 - 3.9e-11 42.5 19.8 3.9e-11 42.5 19.8 1.7 1 1 1 2 2 2 1 Sugar (and other) transporter MMS1_N PF10433.9 EEQ38129.1 - 1.4e-44 152.6 1.0 9.1e-44 149.9 0.3 2.3 2 1 1 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EEQ38129.1 - 0.0031 16.9 0.0 0.0074 15.6 0.0 1.6 1 0 0 1 1 1 1 CPSF A subunit region Lep_receptor_Ig PF06328.11 EEQ38129.1 - 0.048 13.6 1.2 7.3 6.6 0.0 3.0 2 0 0 2 2 2 0 Ig-like C2-type domain FH2 PF02181.23 EEQ38131.1 - 1.8e-88 297.2 11.1 1.8e-88 297.2 11.1 3.1 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EEQ38131.1 - 2.3e-43 148.1 1.0 2.3e-43 148.1 1.0 4.2 3 0 0 3 3 3 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 EEQ38131.1 - 1.5e-34 119.2 0.0 1.5e-34 119.2 0.0 3.6 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Sec2p PF06428.11 EEQ38132.1 - 8.5e-28 96.2 7.3 8.5e-28 96.2 7.3 2.8 1 1 1 2 2 2 1 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 EEQ38132.1 - 0.0014 17.6 21.9 0.0016 17.4 12.8 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein ATG16 PF08614.11 EEQ38132.1 - 0.021 15.0 23.0 0.026 14.7 20.8 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-H PF05837.12 EEQ38132.1 - 0.022 15.2 19.2 0.049 14.1 7.8 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) GAS PF13851.6 EEQ38132.1 - 0.026 13.9 15.3 0.045 13.1 13.9 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 EEQ38132.1 - 0.071 12.6 16.5 0.13 11.7 14.7 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 Rota_NS6 PF04866.12 EEQ38132.1 - 0.18 12.0 0.1 35 4.7 0.0 2.6 2 0 0 2 2 2 0 Rotavirus non-structural protein 6 Uso1_p115_C PF04871.13 EEQ38132.1 - 0.18 12.2 23.5 0.055 13.8 15.5 2.6 2 1 1 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HIP1_clath_bdg PF16515.5 EEQ38132.1 - 0.21 12.2 19.3 0.28 11.8 11.0 2.8 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAM76 PF16046.5 EEQ38132.1 - 0.25 10.7 8.1 0.44 9.9 8.1 1.4 1 0 0 1 1 1 0 FAM76 protein Csm1_N PF18504.1 EEQ38132.1 - 0.25 11.7 13.1 0.74 10.2 0.3 3.5 2 1 0 3 3 3 0 Csm1 N-terminal domain bZIP_2 PF07716.15 EEQ38132.1 - 0.32 11.1 13.9 3 8.0 0.0 4.5 4 1 0 4 4 4 0 Basic region leucine zipper Cob_adeno_trans PF01923.18 EEQ38132.1 - 0.67 10.1 8.2 0.44 10.7 4.0 2.2 1 1 1 2 2 2 0 Cobalamin adenosyltransferase KASH_CCD PF14662.6 EEQ38132.1 - 1.2 8.9 19.5 10 5.9 12.5 2.7 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 EEQ38132.1 - 1.3 9.3 10.1 3.3 8.1 4.6 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cep57_CLD_2 PF14197.6 EEQ38132.1 - 1.5 9.0 22.9 0.58 10.3 11.6 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Filament PF00038.21 EEQ38132.1 - 1.6 8.3 17.5 29 4.1 17.5 2.7 1 1 0 1 1 1 0 Intermediate filament protein V_ATPase_I PF01496.19 EEQ38132.1 - 1.8 6.4 5.4 2.3 6.0 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4201 PF13870.6 EEQ38132.1 - 2 8.1 17.6 0.8 9.4 3.3 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Laminin_II PF06009.12 EEQ38132.1 - 2.1 8.3 10.5 0.33 11.0 1.8 2.6 1 1 1 3 3 3 0 Laminin Domain II DUF3584 PF12128.8 EEQ38132.1 - 2.3 5.6 18.7 3.3 5.1 18.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 EEQ38132.1 - 2.4 8.4 20.6 5.2 7.3 12.5 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4763 PF15960.5 EEQ38132.1 - 2.5 7.4 10.6 5.9 6.1 9.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF4404 PF14357.6 EEQ38132.1 - 3.9 8.2 14.5 6.5 7.5 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) TPR_MLP1_2 PF07926.12 EEQ38132.1 - 4.1 7.5 23.4 0.42 10.7 11.4 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 EEQ38132.1 - 4.2 7.8 17.9 28 5.1 18.0 2.1 1 1 0 1 1 1 0 Fez1 DivIC PF04977.15 EEQ38132.1 - 4.3 7.2 19.5 11 5.8 2.5 4.5 1 1 4 5 5 5 0 Septum formation initiator DUF641 PF04859.12 EEQ38132.1 - 4.5 7.6 14.0 0.49 10.7 0.5 3.0 2 1 0 3 3 2 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.6 EEQ38132.1 - 4.6 5.8 12.0 7.2 5.1 12.0 1.2 1 0 0 1 1 1 0 AAA domain UPF0242 PF06785.11 EEQ38132.1 - 6.2 6.9 17.9 4.5 7.3 9.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus F-box-like PF12937.7 EEQ38133.1 - 0.00098 19.0 0.1 0.0034 17.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EEQ38133.1 - 0.0046 16.8 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 F-box LRR_8 PF13855.6 EEQ38133.1 - 0.14 11.9 1.6 2.6 7.9 0.0 3.7 5 0 0 5 5 5 0 Leucine rich repeat DUF1182 PF06681.13 EEQ38135.1 - 0.025 14.2 0.1 0.034 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) zf-C2H2 PF00096.26 EEQ38136.1 - 0.08 13.4 1.5 0.23 12.0 1.5 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 EEQ38136.1 - 0.16 12.6 0.1 0.16 12.6 0.1 3.7 4 1 0 4 4 4 0 FOXP coiled-coil domain Exonuc_VII_L PF02601.15 EEQ38136.1 - 0.21 11.1 1.8 0.22 11.1 0.2 1.7 2 0 0 2 2 2 0 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 EEQ38137.1 - 4.1e-31 107.6 18.7 4.1e-31 107.6 18.7 6.9 2 1 4 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EEQ38137.1 - 5.1e-17 61.6 12.7 5.1e-17 61.6 12.7 10.4 5 5 4 9 9 9 4 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EEQ38137.1 - 0.00027 21.2 31.8 0.00049 20.4 9.3 5.3 2 1 3 5 5 5 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EEQ38137.1 - 0.0035 17.4 11.2 0.0035 17.4 11.2 6.5 3 2 3 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 EEQ38137.1 - 0.0092 15.8 48.7 0.014 15.3 4.5 7.9 6 2 1 7 7 7 4 GIT coiled-coil Rho guanine nucleotide exchange factor DUF948 PF06103.11 EEQ38137.1 - 0.017 15.4 1.2 0.017 15.4 1.2 6.5 4 3 3 7 7 7 0 Bacterial protein of unknown function (DUF948) BLM10_mid PF16507.5 EEQ38138.1 - 2e-166 554.7 0.0 4.5e-166 553.6 0.0 1.6 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EEQ38138.1 - 2.4e-24 85.0 0.0 6.9e-24 83.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EEQ38138.1 - 1.3e-20 73.5 0.0 4.5e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal IBN_N PF03810.19 EEQ38139.1 - 2.8e-15 56.0 0.0 1.2e-14 53.9 0.0 2.2 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EEQ38139.1 - 0.0068 16.5 4.7 0.05 13.7 0.0 3.5 4 0 0 4 4 4 1 Exportin 1-like protein Pribosyltran PF00156.27 EEQ38140.1 - 6e-10 38.9 0.0 7.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF4938 PF16292.5 EEQ38140.1 - 0.065 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4938) Utp12 PF04003.12 EEQ38141.1 - 1.4e-19 70.3 0.3 2.9e-19 69.3 0.3 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family ABC_tran PF00005.27 EEQ38142.1 - 3.4e-47 160.4 0.0 1.4e-22 80.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EEQ38142.1 - 7e-22 77.3 2.0 7e-22 77.3 2.0 3.3 3 1 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 EEQ38142.1 - 2.6e-17 63.6 7.5 2.3e-05 24.3 0.0 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ38142.1 - 2.1e-10 40.4 0.3 0.3 10.5 0.0 4.4 3 1 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ38142.1 - 1.5e-08 34.2 0.0 0.00053 19.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ38142.1 - 1.1e-07 32.3 2.7 0.00036 21.0 0.0 3.0 3 1 0 3 3 2 2 AAA ATPase domain AAA_15 PF13175.6 EEQ38142.1 - 6.3e-06 26.1 4.4 0.012 15.4 0.0 3.9 4 1 1 5 5 5 2 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ38142.1 - 1.5e-05 25.0 0.3 0.063 13.2 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_23 PF13476.6 EEQ38142.1 - 1.7e-05 25.4 10.2 0.11 13.0 0.0 4.0 4 0 0 4 4 4 2 AAA domain NACHT PF05729.12 EEQ38142.1 - 1.8e-05 24.8 0.1 0.17 11.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 EEQ38142.1 - 2.7e-05 24.5 0.7 0.034 14.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EEQ38142.1 - 4.2e-05 23.8 0.0 0.4 10.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EEQ38142.1 - 5.6e-05 22.9 0.1 0.089 12.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EEQ38142.1 - 0.00013 22.3 0.0 0.83 10.1 0.0 3.2 3 0 0 3 3 3 2 RNA helicase AAA_5 PF07728.14 EEQ38142.1 - 0.00016 21.7 0.1 0.75 9.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EEQ38142.1 - 0.00087 19.4 0.1 3.1 7.9 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase NB-ARC PF00931.22 EEQ38142.1 - 0.001 18.3 0.1 0.91 8.7 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain AAA PF00004.29 EEQ38142.1 - 0.0013 19.2 0.0 1.3 9.4 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EEQ38142.1 - 0.0018 18.5 0.8 3.1 8.0 0.0 3.3 4 0 0 4 4 2 1 AAA domain AAA_14 PF13173.6 EEQ38142.1 - 0.0021 18.1 0.0 2.2 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 EEQ38142.1 - 0.0024 18.1 0.4 3.4 7.9 0.0 2.9 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase Rad17 PF03215.15 EEQ38142.1 - 0.0025 17.8 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain MCM PF00493.23 EEQ38142.1 - 0.0035 16.5 0.0 0.77 8.8 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain AAA_25 PF13481.6 EEQ38142.1 - 0.0042 16.7 0.1 6.5 6.3 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EEQ38142.1 - 0.0048 17.4 0.0 3.2 8.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 EEQ38142.1 - 0.01 15.0 0.6 3.1 6.9 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF815) DUF2813 PF11398.8 EEQ38142.1 - 0.014 14.7 0.1 4.8 6.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_7 PF12775.7 EEQ38142.1 - 0.025 14.1 0.1 4.4 6.8 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region G-alpha PF00503.20 EEQ38142.1 - 0.028 13.6 0.9 5.9 5.9 0.0 2.9 3 1 1 4 4 4 0 G-protein alpha subunit Ras PF00071.22 EEQ38142.1 - 0.04 13.5 0.0 5 6.7 0.0 2.5 2 0 0 2 2 2 0 Ras family DLIC PF05783.11 EEQ38142.1 - 0.046 12.6 0.1 0.71 8.6 0.0 2.3 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Mg_chelatase PF01078.21 EEQ38142.1 - 0.048 13.0 0.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Septin PF00735.18 EEQ38142.1 - 0.058 12.7 0.0 8.5 5.6 0.0 2.5 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 EEQ38142.1 - 0.065 13.0 0.6 10 5.8 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EEQ38142.1 - 0.092 12.5 2.5 2.2 7.9 0.0 3.6 4 1 0 4 4 3 0 AAA domain T2SSE PF00437.20 EEQ38142.1 - 0.12 11.5 0.0 0.42 9.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 EEQ38142.1 - 0.2 11.7 5.3 5.9 6.9 0.0 3.8 3 1 1 4 4 3 0 Dynamin family ATPase_2 PF01637.18 EEQ38142.1 - 0.35 10.7 3.7 8.7 6.2 0.0 3.3 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea eIF3_N PF09440.10 EEQ38142.1 - 0.96 9.9 5.2 0.59 10.6 0.4 2.3 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF87 PF01935.17 EEQ38142.1 - 1.5 8.8 6.7 16 5.5 0.0 4.1 3 1 2 5 5 5 0 Helicase HerA, central domain D5_N PF08706.11 EEQ38142.1 - 7.1 6.9 6.6 3.1 8.1 0.1 2.3 2 0 0 2 2 2 0 D5 N terminal like AA_kinase PF00696.28 EEQ38143.1 - 9.8e-36 123.6 2.5 1.5e-35 123.0 2.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EEQ38143.1 - 2.6e-14 52.9 0.0 8.3e-14 51.3 0.0 1.9 1 0 0 1 1 1 1 PUA domain CNH PF00780.22 EEQ38144.1 - 3.5e-07 30.1 0.0 6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 EEQ38144.1 - 0.00016 22.1 0.4 0.00097 19.6 0.0 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 UbiA PF01040.18 EEQ38145.1 - 1.9e-51 174.8 16.4 2.5e-51 174.4 16.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-ANAPC11 PF12861.7 EEQ38146.1 - 1.6e-43 146.7 6.6 1.9e-43 146.4 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEQ38146.1 - 4.4e-21 74.9 9.2 6.4e-21 74.4 9.2 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ38146.1 - 6.3e-07 29.6 15.6 1.3e-05 25.4 15.8 2.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ38146.1 - 0.00011 21.9 4.8 0.00011 21.9 4.8 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EEQ38146.1 - 0.0011 18.7 10.4 0.011 15.5 0.9 3.1 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EEQ38146.1 - 0.0011 18.9 9.1 0.015 15.3 6.6 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEQ38146.1 - 0.0011 18.7 13.7 0.0044 16.9 13.7 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EEQ38146.1 - 0.0048 16.9 4.0 0.041 13.9 0.3 2.3 2 0 0 2 2 2 1 Double zinc ribbon zf-C3HC4_4 PF15227.6 EEQ38146.1 - 0.005 17.0 1.2 0.005 17.0 1.2 2.2 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING PHD PF00628.29 EEQ38146.1 - 0.028 14.3 6.3 0.028 14.3 6.3 1.7 2 0 0 2 2 2 0 PHD-finger Rtf2 PF04641.12 EEQ38146.1 - 0.11 11.8 0.4 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zf-HIT PF04438.16 EEQ38146.1 - 0.17 11.8 9.2 0.078 12.9 4.4 2.1 2 0 0 2 2 2 0 HIT zinc finger Zn_ribbon_17 PF17120.5 EEQ38146.1 - 0.39 10.4 10.8 6.3 6.5 10.8 2.2 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Rad50_zn_hook PF04423.14 EEQ38146.1 - 0.54 10.1 0.0 0.54 10.1 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_3 PF13920.6 EEQ38146.1 - 0.55 10.1 12.3 4.1 7.4 8.6 2.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ38146.1 - 0.71 9.9 12.6 3.5 7.7 12.6 2.2 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_11 PF17123.5 EEQ38146.1 - 0.83 9.5 10.0 8.3 6.3 10.0 2.5 1 1 0 1 1 1 0 RING-like zinc finger FANCL_C PF11793.8 EEQ38146.1 - 1 9.6 18.0 0.17 12.1 4.9 3.2 2 2 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H_2 PF13832.6 EEQ38146.1 - 1.3 9.2 7.2 0.82 9.9 3.7 2.1 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 EEQ38146.1 - 1.8 8.9 10.4 15 6.0 10.5 2.3 1 1 1 2 2 2 0 RING-like domain RINGv PF12906.7 EEQ38146.1 - 2.4 8.3 12.1 0.24 11.6 5.1 2.3 2 0 0 2 2 2 0 RING-variant domain BPL_N PF09825.9 EEQ38147.1 - 1.9e-137 458.4 0.0 2.4e-137 458.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EEQ38147.1 - 8.2e-15 54.9 0.0 1.3e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EEQ38147.1 - 5.1e-07 29.5 0.1 9.4e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain ThuA PF06283.11 EEQ38147.1 - 0.017 15.4 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation PIH1 PF08190.12 EEQ38148.1 - 1.1e-22 80.3 0.2 2.4e-22 79.2 0.2 1.5 1 0 0 1 1 1 1 PIH1 N-terminal domain Pih1_fungal_CS PF18482.1 EEQ38148.1 - 0.12 13.0 0.1 0.25 11.9 0.1 1.6 1 0 0 1 1 1 0 Fungal Pih1 CS domain MatE PF01554.18 EEQ38149.1 - 2.6e-57 193.0 24.9 3.6e-31 108.0 7.2 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EEQ38149.1 - 2.7e-06 27.5 11.8 2.7e-06 27.5 11.8 3.4 3 0 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain LTV PF04180.14 EEQ38150.1 - 5.2e-116 388.5 29.4 6e-116 388.3 29.4 1.0 1 0 0 1 1 1 1 Low temperature viability protein Peptidase_M1 PF01433.20 EEQ38151.1 - 1.9e-70 236.9 2.3 3.6e-70 235.9 2.3 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EEQ38151.1 - 3.9e-47 161.3 0.1 5.7e-47 160.8 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EEQ38151.1 - 1.6e-36 126.3 0.6 4.9e-24 85.5 0.1 2.5 1 1 1 2 2 2 2 Peptidase M1 N-terminal domain Pkinase PF00069.25 EEQ38152.1 - 1.6e-64 217.8 0.1 1.9e-64 217.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38152.1 - 5.1e-20 71.8 0.0 7.4e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ38152.1 - 1.4e-07 31.7 0.0 6.1e-07 29.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ38152.1 - 0.014 15.0 0.3 0.025 14.2 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EEQ38152.1 - 0.044 12.6 0.0 0.065 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EEQ38152.1 - 0.052 12.6 0.1 0.092 11.8 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EEQ38152.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Neur_chan_memb PF02932.16 EEQ38153.1 - 1.3 9.1 4.8 1.9 8.5 4.8 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pro_isomerase PF00160.21 EEQ38154.1 - 1.3e-47 162.0 0.2 2.5e-47 161.1 0.2 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 EEQ38154.1 - 2.6e-08 33.3 9.4 2.6e-05 23.8 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ38154.1 - 5.8e-08 32.3 7.7 0.0008 19.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ38154.1 - 0.00085 20.0 2.5 0.026 15.3 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ38154.1 - 0.0013 18.8 0.1 0.0013 18.8 0.1 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EEQ38154.1 - 0.016 15.3 0.4 0.016 15.3 0.4 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EEQ38154.1 - 0.031 14.6 1.9 0.45 10.8 0.6 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ38154.1 - 0.073 13.7 4.8 0.058 14.1 2.5 2.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ38154.1 - 0.36 11.4 4.5 1.7 9.2 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ38154.1 - 2.6 8.9 4.3 62 4.5 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 EEQ38155.1 - 2.9e-25 88.9 22.1 2.9e-25 88.9 22.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.20 EEQ38156.1 - 6.9e-17 61.9 0.1 1.3e-15 57.8 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ38156.1 - 3e-14 52.9 0.1 7.4e-14 51.6 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ38156.1 - 5e-14 53.4 0.0 7e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EEQ38156.1 - 7.5e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 EEQ38156.1 - 0.00065 19.2 0.1 0.048 13.1 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EEQ38156.1 - 0.00066 19.6 0.5 5.6 6.7 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EEQ38156.1 - 0.0031 17.2 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 EEQ38156.1 - 0.0036 17.1 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EEQ38156.1 - 0.0075 16.2 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EEQ38156.1 - 0.0081 15.8 0.1 0.014 15.1 0.0 1.3 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 EEQ38156.1 - 0.013 15.0 0.0 1.7 8.2 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Ser_hydrolase PF06821.13 EEQ38156.1 - 0.024 14.5 0.1 0.068 13.0 0.1 1.8 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_5 PF12695.7 EEQ38156.1 - 0.043 13.6 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EEQ38156.1 - 0.084 12.4 0.0 1 8.9 0.0 2.0 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Fungal_trans PF04082.18 EEQ38157.1 - 3e-22 78.9 0.0 5.3e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ38157.1 - 4.5e-07 29.9 8.1 8.4e-07 29.0 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4907 PF16250.5 EEQ38157.1 - 0.15 12.0 0.2 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4907) MFS_1 PF07690.16 EEQ38158.1 - 1.4e-40 139.3 15.5 1.8e-40 139.0 15.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1445 PF07286.12 EEQ38159.1 - 5.9e-58 194.9 0.0 7.7e-58 194.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) DUF3913 PF13052.6 EEQ38159.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) Hydantoinase_A PF01968.18 EEQ38160.1 - 5.9e-106 354.0 0.0 7.9e-106 353.5 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EEQ38160.1 - 3.6e-45 153.8 0.2 4e-43 147.2 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Hydantoinase_B PF02538.14 EEQ38160.1 - 4.7e-38 130.9 0.0 9.5e-38 129.9 0.0 1.5 2 0 0 2 2 2 1 Hydantoinase B/oxoprolinase Hydantoinase_B PF02538.14 EEQ38163.1 - 1.8e-83 280.7 0.0 2.2e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Tubulin_3 PF14881.6 EEQ38163.1 - 0.057 13.1 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Tubulin domain Hydantoinase_B PF02538.14 EEQ38164.1 - 3.4e-43 147.8 2.9 3.9e-43 147.7 2.9 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase GalP_UDP_tr_C PF02744.17 EEQ38166.1 - 1.4e-65 220.1 0.1 3.3e-65 218.9 0.1 1.5 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 EEQ38166.1 - 1.2e-33 117.1 0.2 5e-33 115.1 0.2 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.23 EEQ38166.1 - 0.0044 17.7 0.0 0.015 16.0 0.0 1.9 2 0 0 2 2 2 1 HIT domain AHSP PF09236.10 EEQ38166.1 - 0.017 15.5 0.1 0.078 13.4 0.0 2.1 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein GalP_UDP_transf PF01087.22 EEQ38167.1 - 3.6e-31 109.0 0.6 5.3e-31 108.5 0.6 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 EEQ38167.1 - 0.011 14.6 0.1 0.015 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) GDP_Man_Dehyd PF16363.5 EEQ38168.1 - 2.7e-63 214.4 0.0 3.2e-63 214.1 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EEQ38168.1 - 7.2e-46 156.6 0.0 9.1e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EEQ38168.1 - 4.4e-13 49.0 0.0 3.5e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EEQ38168.1 - 3.7e-08 32.8 0.0 8.4e-08 31.6 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EEQ38168.1 - 1e-07 31.4 0.0 1.6e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EEQ38168.1 - 1.3e-07 30.9 0.0 2.6e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EEQ38168.1 - 0.056 12.9 0.0 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EEQ38168.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EEQ38169.1 - 3.4e-51 174.6 0.0 4.7e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EEQ38169.1 - 1.2e-48 165.7 0.0 1.6e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Aldose_epim PF01263.20 EEQ38169.1 - 2e-32 112.7 0.3 3.7e-32 111.8 0.2 1.5 2 0 0 2 2 2 1 Aldose 1-epimerase 3Beta_HSD PF01073.19 EEQ38169.1 - 1.4e-16 60.3 0.1 4.5e-16 58.7 0.1 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EEQ38169.1 - 1.6e-15 57.0 0.0 5.9e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EEQ38169.1 - 4.5e-09 35.8 0.0 7.5e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EEQ38169.1 - 8.7e-07 28.4 0.0 0.00026 20.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein KR PF08659.10 EEQ38169.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EEQ38169.1 - 4.2e-06 26.4 0.0 6.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EEQ38169.1 - 1.8e-05 24.7 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ38169.1 - 0.0008 19.0 0.3 0.0018 17.9 0.3 1.6 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 EEQ38169.1 - 0.11 12.1 0.4 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GalKase_gal_bdg PF10509.9 EEQ38170.1 - 1.2e-21 76.0 0.0 2.2e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EEQ38170.1 - 8e-15 54.8 0.1 1.6e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Flavi_NS2A PF01005.19 EEQ38170.1 - 0.18 12.0 0.0 0.26 11.4 0.0 1.2 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A GHMP_kinases_C PF08544.13 EEQ38172.1 - 2.6e-11 43.7 0.0 5.9e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 GHMP kinases C terminal HTH_Mga PF08280.11 EEQ38172.1 - 0.12 12.4 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Sugar_tr PF00083.24 EEQ38174.1 - 4.7e-106 355.3 25.3 6.2e-106 355.0 25.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ38174.1 - 3.7e-25 88.6 24.1 1.5e-24 86.6 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EEQ38174.1 - 0.065 13.8 0.2 0.16 12.5 0.2 1.6 1 0 0 1 1 1 0 Phage holin family 2 Lipase_GDSL_2 PF13472.6 EEQ38175.1 - 3.9e-28 99.0 0.0 5.2e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EEQ38175.1 - 2.9e-20 73.1 0.1 4.2e-20 72.6 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cellulase PF00150.18 EEQ38175.1 - 0.0072 15.8 0.1 0.0098 15.3 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GLEYA PF10528.9 EEQ38177.1 - 5.1e-14 52.5 0.7 5.1e-14 52.5 0.7 1.9 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 EEQ38177.1 - 1.7e-07 31.2 1.0 3e-07 30.3 0.1 1.9 2 1 0 2 2 2 1 PA14 domain MFS_1 PF07690.16 EEQ38179.1 - 6.6e-41 140.4 28.9 6.6e-41 140.4 28.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ38179.1 - 7.8e-15 54.7 8.3 7.8e-15 54.7 8.3 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter p450 PF00067.22 EEQ38180.1 - 2.7e-49 168.2 0.0 3.4e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.8 EEQ38181.1 - 1.2e-14 54.0 0.7 4.5e-14 52.1 0.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain CLP1_P PF16575.5 EEQ38182.1 - 1e-34 120.0 0.0 2.6e-34 118.7 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 EEQ38182.1 - 5.2e-05 23.3 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EEQ38182.1 - 0.0008 19.8 0.0 0.0074 16.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Septin PF00735.18 EEQ38182.1 - 0.0021 17.4 0.0 0.0045 16.3 0.0 1.4 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.18 EEQ38182.1 - 0.0082 15.5 0.0 0.025 13.9 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family CbiA PF01656.23 EEQ38182.1 - 0.0095 16.0 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATPase_2 PF01637.18 EEQ38182.1 - 0.063 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 EEQ38182.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EEQ38182.1 - 0.073 13.1 0.0 0.43 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EEQ38182.1 - 0.074 13.6 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 EEQ38182.1 - 0.091 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 EEQ38182.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EEQ38182.1 - 0.17 11.8 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 EEQ38182.1 - 0.18 12.2 0.0 1 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Prominin PF05478.11 EEQ38183.1 - 0.023 12.7 9.0 0.029 12.3 9.0 1.1 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 EEQ38183.1 - 0.03 11.9 9.5 0.044 11.3 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SesA PF17107.5 EEQ38183.1 - 0.041 14.1 2.3 0.045 13.9 0.4 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF4088 PF13317.6 EEQ38183.1 - 0.097 12.2 0.5 0.16 11.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) STAT_alpha PF01017.20 EEQ38183.1 - 0.17 11.8 8.0 0.31 10.9 8.0 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain muHD PF10291.9 EEQ38184.1 - 1.5e-50 172.1 0.3 1.5e-50 172.1 0.3 1.7 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Chorion_S16 PF05836.12 EEQ38184.1 - 0.14 12.4 0.0 0.74 10.1 0.0 2.2 2 0 0 2 2 2 0 Chorion protein S16 Ammonium_transp PF00909.21 EEQ38185.1 - 1.4e-113 379.6 31.0 1.8e-113 379.3 31.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family O_anti_polymase PF01901.16 EEQ38185.1 - 0.029 13.6 1.3 0.59 9.3 0.1 2.3 2 0 0 2 2 2 0 Putative O-antigen polymerase UPF0183 PF03676.14 EEQ38186.1 - 1.5e-52 179.2 0.0 1e-51 176.5 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) LRR_9 PF14580.6 EEQ38187.1 - 1.5e-32 112.5 0.3 2e-32 112.1 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EEQ38187.1 - 1e-07 32.1 20.5 3.7e-07 30.4 7.8 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEQ38187.1 - 0.00027 20.7 16.6 0.00053 19.7 9.2 3.3 2 1 2 4 4 4 2 Leucine rich repeat UPF0128 PF03673.13 EEQ38187.1 - 0.077 12.5 0.5 0.96 8.9 0.0 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0128) DUF1854 PF08909.11 EEQ38187.1 - 0.1 12.4 0.2 0.2 11.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) GTSE1_N PF15259.6 EEQ38187.1 - 0.42 10.8 3.2 0.58 10.3 3.2 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 BAH PF01426.18 EEQ38189.1 - 4.3e-10 39.5 0.8 1.7e-09 37.6 0.2 2.3 2 0 0 2 2 2 1 BAH domain PHD PF00628.29 EEQ38189.1 - 3.8e-08 33.1 11.3 3.8e-08 33.1 11.3 1.7 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 EEQ38189.1 - 0.43 11.0 11.7 1.2 9.5 11.7 1.9 1 0 0 1 1 1 0 Ring finger domain Zf_RING PF16744.5 EEQ38189.1 - 0.87 9.7 11.9 7.8 6.7 11.9 2.3 1 1 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 EEQ38191.1 - 2.6e-07 30.4 6.3 2.6e-07 30.4 6.3 5.5 6 1 0 6 6 6 3 PHD-finger zf-HC5HC2H PF13771.6 EEQ38191.1 - 1.8e-06 28.1 3.2 1.8e-06 28.1 3.2 3.9 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EEQ38191.1 - 2.7e-05 23.6 1.5 2.7e-05 23.6 1.5 5.1 6 0 0 6 6 6 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EEQ38191.1 - 6.4e-05 23.1 7.6 6.4e-05 23.1 7.6 3.9 3 1 0 3 3 3 1 PHD-zinc-finger like domain C1_2 PF03107.16 EEQ38191.1 - 0.0098 16.2 0.5 0.0098 16.2 0.5 5.0 5 0 0 5 5 5 3 C1 domain DUF2387 PF09526.10 EEQ38191.1 - 0.027 14.6 0.6 0.23 11.6 0.1 3.0 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) DUF2197 PF09963.9 EEQ38191.1 - 0.93 9.8 3.6 25 5.2 0.1 3.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2197) PCM1_C PF15717.5 EEQ38191.1 - 1.3 7.6 13.3 2.5 6.7 13.3 1.4 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Mitofilin PF09731.9 EEQ38191.1 - 1.6 7.5 21.1 2.4 6.9 21.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein mRNA_cap_enzyme PF01331.19 EEQ38192.1 - 7.9e-57 192.2 0.0 1.2e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EEQ38192.1 - 9.5e-33 113.1 0.2 2.3e-32 111.8 0.2 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EEQ38192.1 - 4.5e-06 26.4 0.0 0.011 15.4 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Prefoldin_2 PF01920.20 EEQ38193.1 - 1e-23 83.3 11.6 1.2e-23 83.1 11.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF4515 PF14988.6 EEQ38193.1 - 5.3e-05 23.1 5.6 0.025 14.4 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4515) Prefoldin PF02996.17 EEQ38193.1 - 0.00029 20.7 9.4 0.0013 18.6 9.4 1.8 1 1 0 1 1 1 1 Prefoldin subunit Seryl_tRNA_N PF02403.22 EEQ38193.1 - 0.0015 18.8 7.6 0.036 14.3 0.8 2.1 2 0 0 2 2 2 2 Seryl-tRNA synthetase N-terminal domain Cnn_1N PF07989.11 EEQ38193.1 - 0.0038 17.4 10.3 0.0095 16.1 7.4 2.1 1 1 1 2 2 2 1 Centrosomin N-terminal motif 1 Csm1_N PF18504.1 EEQ38193.1 - 0.0058 16.9 0.8 0.0058 16.9 0.8 2.3 2 1 0 2 2 2 1 Csm1 N-terminal domain Vps51 PF08700.11 EEQ38193.1 - 0.0066 16.5 2.6 0.03 14.4 2.5 2.2 1 1 0 1 1 1 1 Vps51/Vps67 MbeD_MobD PF04899.12 EEQ38193.1 - 0.0068 16.5 1.1 0.36 11.0 0.1 2.3 2 0 0 2 2 2 1 MbeD/MobD like ZapB PF06005.12 EEQ38193.1 - 0.0073 16.7 10.2 0.025 15.0 1.2 2.3 2 0 0 2 2 2 1 Cell division protein ZapB UPF0242 PF06785.11 EEQ38193.1 - 0.0075 16.4 6.8 0.01 16.0 6.8 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DivIVA PF05103.13 EEQ38193.1 - 0.0093 16.1 8.8 0.017 15.2 1.6 2.1 2 0 0 2 2 2 1 DivIVA protein 5_nucleotid PF05761.14 EEQ38193.1 - 0.014 14.4 1.4 0.019 13.9 1.4 1.1 1 0 0 1 1 1 0 5' nucleotidase family bZIP_1 PF00170.21 EEQ38193.1 - 0.015 15.4 0.8 0.015 15.4 0.8 2.6 2 1 1 3 3 3 0 bZIP transcription factor KfrA_N PF11740.8 EEQ38193.1 - 0.017 15.8 1.4 1.8 9.3 0.1 2.1 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term BLOC1_2 PF10046.9 EEQ38193.1 - 0.017 15.4 10.3 0.027 14.7 1.4 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_C PF07195.12 EEQ38193.1 - 0.019 14.4 2.6 0.039 13.4 2.6 1.7 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DivIC PF04977.15 EEQ38193.1 - 0.019 14.7 13.6 0.26 11.1 1.9 2.7 2 1 1 3 3 3 0 Septum formation initiator CLZ PF16526.5 EEQ38193.1 - 0.021 15.2 0.7 0.021 15.2 0.7 2.3 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FlaC_arch PF05377.11 EEQ38193.1 - 0.024 15.0 0.8 0.024 15.0 0.8 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) PI3K_P85_iSH2 PF16454.5 EEQ38193.1 - 0.024 14.2 5.9 0.16 11.5 5.9 2.0 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NPV_P10 PF05531.12 EEQ38193.1 - 0.025 15.0 8.7 0.47 11.0 2.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein COG5 PF10392.9 EEQ38193.1 - 0.039 14.1 6.8 0.1 12.8 1.1 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 TMCO5 PF14992.6 EEQ38193.1 - 0.049 13.2 7.9 0.056 13.0 7.9 1.1 1 0 0 1 1 1 0 TMCO5 family DUF5320 PF17253.2 EEQ38193.1 - 0.053 14.6 2.8 0.92 10.6 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Rho_Binding PF08912.11 EEQ38193.1 - 0.055 14.3 10.7 0.13 13.1 1.7 2.8 2 1 0 2 2 2 0 Rho Binding BRE1 PF08647.11 EEQ38193.1 - 0.064 13.3 7.0 1.4 9.0 1.5 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3450 PF11932.8 EEQ38193.1 - 0.074 12.4 0.6 0.074 12.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) THOC7 PF05615.13 EEQ38193.1 - 0.075 13.3 8.3 0.38 11.0 8.2 1.9 1 1 0 1 1 1 0 Tho complex subunit 7 Spc24 PF08286.11 EEQ38193.1 - 0.078 13.2 8.0 0.094 13.0 0.9 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlxA PF14282.6 EEQ38193.1 - 0.084 12.9 7.8 0.19 11.8 0.6 2.2 2 0 0 2 2 2 0 FlxA-like protein Cob_adeno_trans PF01923.18 EEQ38193.1 - 0.095 12.8 1.5 0.14 12.3 1.5 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Cluap1 PF10234.9 EEQ38193.1 - 0.12 11.8 7.7 0.29 10.5 7.7 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 LPP PF04728.13 EEQ38193.1 - 0.14 12.6 6.8 0.45 10.9 0.8 2.7 2 1 0 2 2 2 0 Lipoprotein leucine-zipper HALZ PF02183.18 EEQ38193.1 - 0.15 12.3 13.2 0.29 11.4 0.6 3.2 2 2 2 4 4 4 0 Homeobox associated leucine zipper ABC_tran_CTD PF16326.5 EEQ38193.1 - 0.16 12.2 0.6 0.16 12.2 0.6 2.6 2 1 0 2 2 2 0 ABC transporter C-terminal domain Uds1 PF15456.6 EEQ38193.1 - 0.17 12.1 3.5 0.76 10.0 0.2 2.2 2 0 0 2 2 2 0 Up-regulated During Septation DUF5082 PF16888.5 EEQ38193.1 - 0.18 12.1 9.3 0.47 10.7 9.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) MRPL52 PF18699.1 EEQ38193.1 - 0.21 11.8 3.6 1.3 9.2 0.3 2.1 2 0 0 2 2 2 0 Mitoribosomal protein mL52 FapA PF03961.13 EEQ38193.1 - 0.21 10.1 7.7 0.51 8.9 7.7 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 EEQ38193.1 - 0.24 11.9 15.7 3.6 8.1 15.0 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 EEQ38193.1 - 0.24 11.4 6.1 1.9 8.5 6.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 EEQ38193.1 - 0.31 11.7 6.2 0.57 10.8 0.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF2570 PF10828.8 EEQ38193.1 - 0.43 10.4 5.0 0.65 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) Atg14 PF10186.9 EEQ38193.1 - 0.58 9.2 3.8 1.3 8.0 3.8 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 EEQ38193.1 - 0.76 8.6 11.6 1.1 8.0 11.6 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4140 PF13600.6 EEQ38193.1 - 0.77 10.2 8.3 1.9 9.0 1.9 2.1 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mod_r PF07200.13 EEQ38193.1 - 1.2 9.3 13.2 37 4.4 13.2 2.0 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Swi5 PF07061.11 EEQ38193.1 - 1.3 9.2 8.3 0.95 9.6 0.4 2.3 2 0 0 2 2 2 0 Swi5 bZIP_2 PF07716.15 EEQ38193.1 - 1.4 9.1 9.8 0.78 9.9 0.4 2.8 2 1 1 3 3 3 0 Basic region leucine zipper DASH_Dam1 PF08653.10 EEQ38193.1 - 1.5 8.7 5.5 1.7 8.5 0.3 2.7 2 1 1 3 3 3 0 DASH complex subunit Dam1 Tropomyosin_1 PF12718.7 EEQ38193.1 - 1.7 8.8 13.4 0.2 11.8 4.6 2.0 1 1 1 2 2 2 0 Tropomyosin like DUF4795 PF16043.5 EEQ38193.1 - 1.8 8.2 9.2 0.49 10.0 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) PCRF PF03462.18 EEQ38193.1 - 2 8.3 8.1 3.8 7.3 8.1 1.4 1 1 0 1 1 1 0 PCRF domain XhlA PF10779.9 EEQ38193.1 - 2.2 8.6 7.5 1 9.6 2.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA MCU PF04678.13 EEQ38193.1 - 2.3 8.3 5.0 7.3 6.7 0.3 2.0 1 1 1 2 2 2 0 Mitochondrial calcium uniporter SlyX PF04102.12 EEQ38193.1 - 2.6 8.7 8.3 1.1 10.0 1.5 2.5 2 1 0 2 2 2 0 SlyX V-SNARE PF05008.15 EEQ38193.1 - 2.6 8.5 9.2 5.3 7.5 1.4 2.1 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus JIP_LZII PF16471.5 EEQ38193.1 - 3.1 8.0 10.5 10 6.4 2.9 2.7 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Med4 PF10018.9 EEQ38193.1 - 6.4 6.4 9.2 0.5 10.0 2.7 1.9 1 1 2 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Acetyltransf_7 PF13508.7 EEQ38194.1 - 1.1e-05 25.8 0.0 2.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ38194.1 - 2.3e-05 24.6 0.0 0.00018 21.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EEQ38194.1 - 0.00019 21.5 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ38194.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein DUF3014 PF11219.8 EEQ38195.1 - 0.055 13.7 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3014) DUF347 PF03988.12 EEQ38195.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) BBS1 PF14779.6 EEQ38195.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Homeobox_KN PF05920.11 EEQ38196.1 - 3.1e-18 65.4 1.5 6.6e-18 64.3 1.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EEQ38196.1 - 1.6e-05 24.7 1.0 2.8e-05 23.9 1.0 1.4 1 0 0 1 1 1 1 Homeodomain Exo70 PF03081.15 EEQ38197.1 - 1.4e-57 195.5 7.7 1.4e-57 195.5 7.7 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Parathyroid PF01279.17 EEQ38197.1 - 0.065 13.8 0.1 12 6.6 0.0 2.7 2 0 0 2 2 2 0 Parathyroid hormone family QIL1 PF15884.5 EEQ38197.1 - 0.31 11.7 1.5 2.5 8.8 0.7 2.8 3 0 0 3 3 3 0 MICOS complex subunit MIC13, QIL1 RNA_lig_T4_1 PF09511.10 EEQ38198.1 - 4.2e-75 252.4 0.7 1.3e-74 250.8 0.1 2.2 3 0 0 3 3 3 1 RNA ligase tRNA_lig_kinase PF08303.11 EEQ38198.1 - 4.4e-36 124.5 0.1 2.9e-35 121.8 0.1 2.2 1 1 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EEQ38198.1 - 7e-22 78.1 0.4 8.4e-20 71.3 0.4 2.4 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 EEQ38199.1 - 8.6e-40 136.6 0.0 1.2e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 EEQ38199.1 - 0.00025 20.6 2.6 0.0026 17.3 0.3 2.1 2 0 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain KTI12 PF08433.10 EEQ38199.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_22 PF13401.6 EEQ38199.1 - 0.052 13.8 0.1 0.19 12.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain dNK PF01712.19 EEQ38199.1 - 0.088 12.7 0.0 0.36 10.6 0.0 2.0 2 1 0 2 2 2 0 Deoxynucleoside kinase AAA_18 PF13238.6 EEQ38199.1 - 0.77 10.3 5.2 0.48 11.0 0.3 2.8 2 1 1 3 3 3 0 AAA domain Fumble PF03630.14 EEQ38200.1 - 6.3e-127 423.3 1.4 7.7e-127 423.0 1.4 1.1 1 0 0 1 1 1 1 Fumble PEX11 PF05648.14 EEQ38201.1 - 1.9e-06 27.5 7.1 0.0026 17.2 5.4 2.5 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) PALP PF00291.25 EEQ38202.1 - 5.4e-66 223.0 0.0 6.9e-66 222.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.18 EEQ38203.1 - 5e-26 91.3 0.3 1.4e-25 89.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ38203.1 - 5.5e-09 36.0 9.0 9.3e-09 35.3 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain dsrm PF00035.26 EEQ38203.1 - 0.15 12.8 0.2 0.88 10.3 0.1 2.2 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF5102 PF17104.5 EEQ38204.1 - 1.4e-24 87.7 16.8 3.2e-24 86.5 16.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF5102) Jnk-SapK_ap_N PF09744.9 EEQ38204.1 - 0.056 13.7 5.6 0.15 12.3 5.6 1.6 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 BRE1 PF08647.11 EEQ38204.1 - 0.08 13.0 5.4 0.2 11.7 5.4 1.7 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase CHASE6_C PF17150.4 EEQ38204.1 - 0.13 12.9 0.9 0.33 11.7 0.9 1.7 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain Pept_tRNA_hydro PF01195.19 EEQ38205.1 - 7.8e-32 110.6 0.2 9.1e-32 110.4 0.2 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DUF3336 PF11815.8 EEQ38206.1 - 1.6e-49 167.2 2.7 2e-49 166.8 1.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EEQ38206.1 - 9.3e-15 55.3 0.1 3.5e-14 53.5 0.1 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase Hydrolase_like PF13242.6 EEQ38207.1 - 0.021 14.9 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like HAD_2 PF13419.6 EEQ38207.1 - 0.069 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase UBA PF00627.31 EEQ38208.1 - 9.8e-26 89.3 3.5 3.8e-13 49.1 0.4 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EEQ38208.1 - 5.5e-15 54.9 0.4 1e-14 54.0 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.11 EEQ38208.1 - 2e-14 53.1 3.3 4.8e-14 51.8 3.3 1.7 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 EEQ38208.1 - 2.4e-06 27.3 1.0 4.8e-06 26.3 1.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3306 PF11748.8 EEQ38208.1 - 0.0016 19.3 2.2 0.0016 19.3 2.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3306) Rad60-SLD_2 PF13881.6 EEQ38208.1 - 0.0019 18.2 0.0 0.004 17.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EEQ38208.1 - 0.0088 16.4 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain WIYLD PF10440.9 EEQ38208.1 - 0.0095 15.7 0.4 0.19 11.5 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin-binding WIYLD domain DUF2407 PF10302.9 EEQ38208.1 - 0.0097 16.5 0.1 0.053 14.1 0.0 2.3 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain UBA_3 PF09288.10 EEQ38208.1 - 0.087 12.7 0.0 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain FeoA PF04023.14 EEQ38208.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 FeoA domain DUF3020 PF11223.8 EEQ38209.1 - 5.8e-21 74.7 7.5 5.8e-21 74.7 7.5 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3020) Creatinase_N_2 PF16189.5 EEQ38210.1 - 1.4e-40 139.1 0.2 1.1e-38 132.9 0.0 2.6 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain Creatinase_N PF01321.18 EEQ38210.1 - 1.6e-11 45.0 0.0 4.2e-10 40.4 0.0 2.5 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EEQ38210.1 - 3.2e-07 30.2 0.0 5.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 SMC_N PF02463.19 EEQ38211.1 - 1.6e-49 168.3 14.7 3.8e-49 167.1 14.7 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEQ38211.1 - 3.5e-25 88.6 1.4 7.6e-25 87.5 0.4 2.2 2 1 1 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EEQ38211.1 - 2.6e-12 47.2 9.3 1.7e-05 24.8 0.5 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEQ38211.1 - 2.3e-10 40.8 16.4 2.3e-10 40.8 16.4 5.1 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 EEQ38211.1 - 1.8e-07 30.8 0.1 4e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EEQ38211.1 - 0.00084 19.9 108.1 13 6.2 58.1 6.9 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.27 EEQ38211.1 - 0.044 14.3 0.0 0.044 14.3 0.0 5.7 4 3 0 5 5 5 0 ABC transporter MukB PF04310.12 EEQ38211.1 - 0.76 9.5 0.0 0.76 9.5 0.0 4.4 5 2 1 6 6 6 0 MukB N-terminal DUF4407 PF14362.6 EEQ38211.1 - 2.5 7.4 60.4 0.19 11.1 5.5 5.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4407) tRNA_U5-meth_tr PF05958.11 EEQ38212.1 - 4e-14 52.4 0.0 5.6e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EEQ38212.1 - 5.8e-09 35.9 0.1 1.8e-08 34.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TRAM PF01938.20 EEQ38212.1 - 3.6e-07 30.1 0.1 1.6e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 TRAM domain Methyltransf_25 PF13649.6 EEQ38212.1 - 1.1e-05 26.0 0.0 5e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EEQ38212.1 - 5.6e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EEQ38212.1 - 0.00017 21.2 0.0 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EEQ38212.1 - 0.0012 18.9 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ38212.1 - 0.0013 19.3 0.0 0.0054 17.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ38212.1 - 0.0014 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EEQ38212.1 - 0.0024 17.3 0.0 0.0048 16.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EEQ38212.1 - 0.019 15.7 0.0 0.066 14.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 EEQ38212.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.17 EEQ38212.1 - 0.085 12.0 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MIF4G PF02854.19 EEQ38213.1 - 2.5e-23 82.8 4.5 2.5e-19 69.7 3.4 2.8 2 1 0 2 2 2 2 MIF4G domain MA3 PF02847.17 EEQ38213.1 - 2.3e-22 79.1 0.0 8.9e-22 77.2 0.0 2.1 1 0 0 1 1 1 1 MA3 domain AAA PF00004.29 EEQ38214.1 - 2.5e-36 125.0 0.0 5.8e-36 123.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ38214.1 - 2.9e-08 33.4 0.0 6.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ38214.1 - 3.6e-06 27.5 1.0 0.00045 20.6 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EEQ38214.1 - 4.8e-06 26.4 0.0 1.9e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Bac_DnaA PF00308.18 EEQ38214.1 - 2.1e-05 24.4 0.6 0.00059 19.7 0.0 2.4 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_14 PF13173.6 EEQ38214.1 - 2.7e-05 24.2 0.0 0.00011 22.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EEQ38214.1 - 5.7e-05 23.3 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EEQ38214.1 - 6.7e-05 22.9 0.1 0.00087 19.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ38214.1 - 0.0002 21.7 0.9 0.053 13.8 0.0 3.2 1 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EEQ38214.1 - 0.00041 20.5 0.0 0.00078 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.17 EEQ38214.1 - 0.00045 19.4 0.0 0.00072 18.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.17 EEQ38214.1 - 0.0005 19.9 0.0 0.0029 17.4 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 EEQ38214.1 - 0.00082 19.1 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EEQ38214.1 - 0.0012 18.3 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EEQ38214.1 - 0.0014 19.2 0.1 0.004 17.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EEQ38214.1 - 0.0015 18.5 0.6 0.037 13.9 0.1 2.9 2 1 1 3 3 3 1 NACHT domain RNA_helicase PF00910.22 EEQ38214.1 - 0.0024 18.2 0.0 0.0064 16.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 EEQ38214.1 - 0.0027 17.1 0.0 1.4 8.3 0.0 2.5 1 1 1 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 EEQ38214.1 - 0.0032 17.0 0.1 0.018 14.5 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 EEQ38214.1 - 0.0053 16.7 0.3 0.043 13.7 0.3 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 EEQ38214.1 - 0.006 17.0 0.1 0.14 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EEQ38214.1 - 0.009 15.2 0.1 0.019 14.2 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 EEQ38214.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EEQ38214.1 - 0.015 15.4 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 EEQ38214.1 - 0.021 14.0 0.1 0.078 12.1 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain ATPase_2 PF01637.18 EEQ38214.1 - 0.022 14.7 0.1 0.16 11.8 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea ENTH PF01417.20 EEQ38214.1 - 0.022 14.8 0.3 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 ENTH domain ABC_tran PF00005.27 EEQ38214.1 - 0.036 14.6 0.1 0.089 13.3 0.0 1.9 2 1 0 2 2 1 0 ABC transporter Hydin_ADK PF17213.3 EEQ38214.1 - 0.036 14.3 0.1 2.4 8.4 0.0 2.7 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain Sigma54_activat PF00158.26 EEQ38214.1 - 0.043 13.5 0.0 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EEQ38214.1 - 0.064 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EEQ38214.1 - 0.085 12.4 0.1 0.91 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EEQ38214.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 EEQ38214.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EEQ38214.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEQ38214.1 - 0.14 11.9 0.5 0.83 9.4 0.0 2.3 3 0 0 3 3 3 0 AAA domain RNA12 PF10443.9 EEQ38216.1 - 1.3e-147 492.1 3.9 1.8e-95 320.3 0.6 2.4 2 1 1 3 3 3 2 RNA12 protein RRM_1 PF00076.22 EEQ38216.1 - 5.1e-06 26.2 0.0 1.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.9 EEQ38216.1 - 0.00058 19.9 0.1 0.0031 17.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) Sigma70_ner PF04546.13 EEQ38216.1 - 0.0035 17.2 0.1 0.0087 16.0 0.1 1.7 2 0 0 2 2 2 1 Sigma-70, non-essential region CREPT PF16566.5 EEQ38216.1 - 0.031 14.4 2.2 0.032 14.4 0.4 1.9 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Lebercilin PF15619.6 EEQ38216.1 - 6.2 6.4 6.3 0.31 10.7 0.2 1.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Peptidase_C48 PF02902.19 EEQ38217.1 - 2.5e-35 122.3 1.0 3.9e-35 121.7 1.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain VTC PF09359.10 EEQ38218.1 - 3.2e-87 292.4 3.8 3.2e-87 292.4 3.8 1.6 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 EEQ38218.1 - 4.2e-11 43.4 27.7 0.00031 20.8 1.6 4.6 4 1 1 5 5 5 4 SPX domain DUF202 PF02656.15 EEQ38218.1 - 1.4e-08 35.1 7.0 1.4e-08 35.1 7.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Clat_adaptor_s PF01217.20 EEQ38219.1 - 1.2e-15 57.7 0.5 1.5e-15 57.3 0.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MAPKK1_Int PF08923.10 EEQ38219.1 - 0.043 13.6 0.5 0.072 12.9 0.5 1.4 1 0 0 1 1 1 0 Mitogen-activated protein kinase kinase 1 interacting Pox_A21 PF05323.12 EEQ38219.1 - 0.072 13.7 0.4 0.12 13.0 0.4 1.4 1 0 0 1 1 1 0 Poxvirus A21 Protein Bromo_TP PF07524.13 EEQ38220.1 - 5e-10 39.3 0.1 1.1e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 EEQ38220.1 - 0.0014 18.7 0.0 0.0039 17.3 0.0 1.8 1 0 0 1 1 1 1 Histone-fold protein TFIID-31kDa PF02291.15 EEQ38220.1 - 0.0088 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Peptidase_C57 PF03290.13 EEQ38220.1 - 0.013 14.2 0.1 0.023 13.4 0.1 1.3 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase Cyclin_N PF00134.23 EEQ38221.1 - 1.5e-10 40.9 0.3 4.3e-10 39.4 0.3 1.7 1 1 0 1 1 1 1 Cyclin, N-terminal domain SDF PF00375.18 EEQ38221.1 - 0.039 13.0 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family Ferric_reduct PF01794.19 EEQ38222.1 - 8.5e-24 84.1 14.7 2.9e-23 82.3 13.6 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ38222.1 - 5.8e-22 78.5 0.0 9.4e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ38222.1 - 1.7e-20 73.1 0.0 2.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain JAB PF01398.21 EEQ38223.1 - 1.3e-12 47.8 0.1 2.9e-12 46.6 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EEQ38223.1 - 0.0063 16.9 2.9 0.012 16.0 2.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF2046 PF09755.9 EEQ38224.1 - 0.047 12.9 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Polysacc_deac_1 PF01522.21 EEQ38225.1 - 3.5e-25 88.3 0.0 5.6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 EEQ38225.1 - 0.034 13.3 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 FMN_red PF03358.15 EEQ38226.1 - 2.3e-10 40.4 0.0 3.4e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EEQ38226.1 - 1.4e-05 24.9 0.1 4.7e-05 23.2 0.0 1.8 2 1 0 2 2 2 1 Flavodoxin-like fold Flavodoxin_5 PF12724.7 EEQ38226.1 - 2.1e-05 24.8 0.0 0.0048 17.1 0.0 2.5 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_1 PF00258.25 EEQ38226.1 - 4.8e-05 23.6 0.1 0.0036 17.5 0.1 2.6 1 1 0 1 1 1 1 Flavodoxin DUF3405 PF11885.8 EEQ38226.1 - 0.61 8.6 3.0 0.87 8.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DUF3292 PF11696.8 EEQ38226.1 - 2.1 6.6 7.6 3 6.1 7.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) RNA_pol_Rpc4 PF05132.14 EEQ38226.1 - 6.7 7.1 12.6 25 5.3 12.6 1.9 1 1 0 1 1 1 0 RNA polymerase III RPC4 FMN_red PF03358.15 EEQ38227.1 - 3.1e-12 46.5 0.0 4.1e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EEQ38227.1 - 0.001 18.8 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EEQ38227.1 - 0.0042 17.3 0.2 0.03 14.5 0.2 2.2 1 1 0 1 1 1 1 Flavodoxin PNP_phzG_C PF10590.9 EEQ38228.1 - 1.9e-18 66.2 0.3 3.7e-18 65.3 0.3 1.5 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EEQ38228.1 - 7e-13 48.6 0.0 1.1e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase GEP5 PF17053.5 EEQ38228.1 - 0.034 14.0 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Genetic interactor of prohibitin 5 Cupin_8 PF13621.6 EEQ38229.1 - 1.8e-14 54.1 0.2 1.5e-13 51.1 0.2 2.1 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EEQ38229.1 - 1.9e-09 38.0 0.2 4.4e-08 33.5 0.2 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 EEQ38229.1 - 1.6e-05 24.7 0.0 3.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like Cupin_4 PF08007.12 EEQ38229.1 - 0.0056 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 EEQ38229.1 - 0.091 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Ribosomal_L32p PF01783.23 EEQ38230.1 - 4.8e-13 49.1 1.8 8.6e-13 48.3 1.8 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 EEQ38230.1 - 0.084 12.3 2.2 0.16 11.4 2.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Septin PF00735.18 EEQ38231.1 - 4.1e-111 370.8 0.3 4.9e-111 370.5 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EEQ38231.1 - 1.6e-09 37.8 0.0 3.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ38231.1 - 1e-06 28.8 0.2 2.6e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 EEQ38231.1 - 3.7e-05 23.1 0.1 6.2e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EEQ38231.1 - 0.00022 20.8 0.5 0.0013 18.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EEQ38231.1 - 0.0007 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Roc PF08477.13 EEQ38231.1 - 0.0012 19.0 0.0 0.0026 18.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EEQ38231.1 - 0.002 18.4 0.1 0.041 14.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ38231.1 - 0.0024 18.3 0.1 0.004 17.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 EEQ38231.1 - 0.0036 17.4 0.8 2.4 8.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.18 EEQ38231.1 - 0.0049 16.3 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.27 EEQ38231.1 - 0.0063 17.0 0.3 0.016 15.8 0.3 1.7 1 1 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 EEQ38231.1 - 0.0093 15.7 0.5 0.1 12.4 0.2 2.6 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Gtr1_RagA PF04670.12 EEQ38231.1 - 0.014 14.8 0.1 0.041 13.2 0.0 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 EEQ38231.1 - 0.016 14.3 0.2 0.026 13.6 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EEQ38231.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 EEQ38231.1 - 0.098 12.1 0.1 0.22 11.0 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 EEQ38231.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Ras PF00071.22 EEQ38231.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Ras family Glyco_transf_8 PF01501.20 EEQ38232.1 - 2.3e-19 69.9 0.1 9.4e-19 68.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 EEQ38232.1 - 0.0048 16.9 0.0 0.0077 16.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 EEQ38232.1 - 0.041 13.2 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 Mannosyltransferase putative Thiamine_BP PF01910.17 EEQ38233.1 - 1.3e-26 92.4 0.1 1.4e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 Thiamine-binding protein Myb_DNA-binding PF00249.31 EEQ38234.1 - 0.013 15.6 0.1 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Mito_carr PF00153.27 EEQ38235.1 - 1.9e-71 236.0 2.0 1.3e-24 85.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ38235.1 - 0.26 10.4 2.1 16 4.5 0.0 3.3 2 2 1 3 3 3 0 Gammaproteobacterial serine protease Mito_carr PF00153.27 EEQ38236.1 - 1.1e-40 137.4 7.0 6.3e-15 54.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ArfGap PF01412.18 EEQ38238.1 - 8.1e-41 138.8 1.2 1.5e-40 137.9 1.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Cyt-b5 PF00173.28 EEQ38239.1 - 4.8e-22 77.9 0.1 6.3e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain bZIP_1 PF00170.21 EEQ38240.1 - 1.3e-05 25.1 14.8 9.3e-05 22.4 14.7 2.1 1 1 1 2 2 2 2 bZIP transcription factor DUF4201 PF13870.6 EEQ38240.1 - 0.0029 17.3 5.2 0.0029 17.3 5.2 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) bZIP_Maf PF03131.17 EEQ38240.1 - 0.038 14.5 6.1 0.074 13.6 6.1 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor DrsE_2 PF13686.6 EEQ38240.1 - 0.069 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 DsrE/DsrF/DrsH-like family YabA PF06156.13 EEQ38240.1 - 0.079 13.6 1.8 0.2 12.3 1.8 1.7 1 1 0 1 1 1 0 Initiation control protein YabA DUF2353 PF09789.9 EEQ38240.1 - 0.11 11.8 8.7 0.15 11.4 8.7 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) V_ATPase_I PF01496.19 EEQ38240.1 - 0.72 7.7 9.4 3.8 5.3 0.1 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family bZIP_2 PF07716.15 EEQ38240.1 - 0.74 9.9 17.9 0.87 9.7 14.2 2.7 2 1 1 3 3 3 0 Basic region leucine zipper DUF4140 PF13600.6 EEQ38240.1 - 0.87 10.1 4.5 2 8.9 4.5 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TPR_1 PF00515.28 EEQ38241.1 - 1.4e-46 154.5 27.6 2.4e-06 27.1 0.5 9.6 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ38241.1 - 7.9e-36 119.3 31.3 1.7e-05 24.5 0.5 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EEQ38241.1 - 9.5e-34 115.1 12.5 9.3e-19 67.1 6.5 3.0 3 0 0 3 3 2 2 STI1 domain TPR_16 PF13432.6 EEQ38241.1 - 7.1e-24 84.2 6.8 8.9e-06 26.3 0.2 5.6 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ38241.1 - 6.9e-22 76.9 18.4 7.8e-05 22.3 0.1 7.5 5 2 2 7 7 7 5 TPR repeat TPR_8 PF13181.6 EEQ38241.1 - 2.5e-19 67.8 22.7 0.008 16.3 0.3 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ38241.1 - 1.5e-18 66.9 19.4 5.2e-07 29.9 0.5 7.3 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ38241.1 - 3.6e-16 58.5 10.8 0.13 13.1 0.1 8.0 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ38241.1 - 3.9e-13 49.7 15.5 0.014 15.9 0.7 6.6 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ38241.1 - 2.4e-09 37.2 1.4 0.00025 21.1 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ38241.1 - 6.3e-09 35.2 12.8 1.4 9.1 0.0 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ38241.1 - 4.8e-08 32.8 13.4 2.5 8.7 0.0 8.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ38241.1 - 4.7e-06 26.3 12.8 0.53 10.2 0.1 6.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ38241.1 - 8.7e-05 22.9 18.3 3.5 8.5 0.0 8.2 8 0 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ38241.1 - 0.0005 20.2 15.2 0.17 12.1 0.7 5.3 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 SHNi-TPR PF10516.9 EEQ38241.1 - 0.00054 19.4 8.7 1.8 8.1 0.0 5.4 5 0 0 5 5 5 1 SHNi-TPR TPR_MalT PF17874.1 EEQ38241.1 - 0.0013 18.2 1.0 37 3.6 0.0 3.6 2 2 0 2 2 2 0 MalT-like TPR region Fis1_TPR_C PF14853.6 EEQ38241.1 - 0.004 17.2 4.8 0.036 14.1 0.0 4.1 5 0 0 5 5 3 1 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 EEQ38241.1 - 0.0088 14.8 0.7 0.0088 14.8 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_21 PF09976.9 EEQ38241.1 - 0.014 15.1 26.1 0.07 12.8 2.4 4.9 2 1 2 5 5 5 0 Tetratricopeptide repeat-like domain Inhibitor_I9 PF05922.16 EEQ38241.1 - 0.016 15.8 2.1 0.025 15.3 0.1 2.3 2 0 0 2 2 1 0 Peptidase inhibitor I9 PPR_2 PF13041.6 EEQ38241.1 - 0.063 13.5 0.2 11 6.3 0.0 3.9 4 0 0 4 4 3 0 PPR repeat family DUF3408 PF11888.8 EEQ38241.1 - 0.26 11.4 7.2 0.77 9.9 7.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF357 PF04010.13 EEQ38241.1 - 0.8 9.8 3.7 4 7.6 0.1 3.7 3 2 0 3 3 3 0 Protein of unknown function (DUF357) BTAD PF03704.17 EEQ38241.1 - 0.92 9.9 14.3 1.4 9.3 0.1 5.2 4 1 0 5 5 5 0 Bacterial transcriptional activator domain Trypan_PARP PF05887.11 EEQ38241.1 - 0.97 9.4 9.5 2.2 8.3 9.5 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RPN7 PF10602.9 EEQ38241.1 - 1.4 8.6 14.3 1.2 8.8 0.1 5.1 3 2 3 6 6 6 0 26S proteasome subunit RPN7 TPR_20 PF14561.6 EEQ38241.1 - 3.6 8.0 10.5 7.1 7.0 0.1 4.7 3 3 2 5 5 5 0 Tetratricopeptide repeat MAS20 PF02064.15 EEQ38241.1 - 4.9 7.3 9.0 6.6 6.8 0.0 3.2 3 0 0 3 3 3 0 MAS20 protein import receptor Alkyl_sulf_dimr PF14863.6 EEQ38241.1 - 6.8 7.1 8.1 9.4 6.7 0.1 4.1 3 2 1 4 4 4 0 Alkyl sulfatase dimerisation Fungal_trans PF04082.18 EEQ38242.1 - 2.8e-06 26.6 3.0 5.5e-06 25.6 3.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 EEQ38243.1 - 1.2e-06 27.8 0.6 2.6e-06 26.7 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ38243.1 - 1.3e-06 28.5 10.5 2.9e-06 27.3 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NARP1 PF12569.8 EEQ38244.1 - 1.4e-120 403.7 26.4 6.5e-95 319.0 1.4 4.9 2 2 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EEQ38244.1 - 1.6e-15 55.9 17.2 0.021 14.9 0.2 8.9 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ38244.1 - 1.8e-14 54.1 16.1 1.4e-05 25.6 0.1 7.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ38244.1 - 4.6e-10 39.9 19.2 0.0053 17.2 1.6 6.6 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ38244.1 - 8.1e-08 32.5 10.8 0.11 13.4 0.1 7.8 8 1 1 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ38244.1 - 4.1e-06 26.9 26.2 0.0006 20.0 4.0 6.8 3 2 4 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EEQ38244.1 - 0.0005 20.3 13.5 0.068 13.5 0.2 6.0 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ38244.1 - 0.00075 19.6 1.7 7.4 6.8 0.0 5.2 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ38244.1 - 0.0011 19.2 12.9 4.6 7.8 0.2 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ38244.1 - 0.012 15.8 16.1 7.5 7.0 0.2 7.0 8 1 0 8 8 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ38244.1 - 0.013 15.3 20.2 22 5.0 0.2 7.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ38244.1 - 0.026 14.2 8.5 0.04 13.6 0.5 4.3 4 0 0 4 4 4 0 TPR repeat Spore_GerAC PF05504.11 EEQ38244.1 - 0.031 14.5 0.9 0.09 13.0 0.0 2.3 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal TPR_7 PF13176.6 EEQ38244.1 - 0.046 13.7 16.7 3.5 7.9 0.0 7.9 9 1 0 9 9 8 0 Tetratricopeptide repeat Sel1 PF08238.12 EEQ38244.1 - 0.11 13.2 1.7 7.8 7.3 0.2 3.5 3 0 0 3 3 3 0 Sel1 repeat Got1 PF04178.12 EEQ38245.1 - 1e-31 109.6 20.0 1.5e-31 109.2 20.0 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 EEQ38245.1 - 0.00031 19.2 11.7 0.00039 18.9 11.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) Blt1 PF12754.7 EEQ38246.1 - 3.7e-05 24.1 1.5 4.4e-05 23.8 1.3 1.3 1 1 0 1 1 1 1 Blt1 N-terminal domain Rad60-SLD_2 PF13881.6 EEQ38246.1 - 0.00031 20.8 0.1 0.00047 20.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like GHL10 PF02638.15 EEQ38246.1 - 0.063 12.4 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 ubiquitin PF00240.23 EEQ38246.1 - 0.1 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family DUF2407 PF10302.9 EEQ38246.1 - 0.13 12.8 0.0 0.19 12.3 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain NCE101 PF11654.8 EEQ38247.1 - 2.6e-21 75.0 0.1 2.9e-21 74.9 0.1 1.0 1 0 0 1 1 1 1 Non-classical export protein 1 HpuA PF16960.5 EEQ38247.1 - 0.059 12.5 0.0 0.067 12.3 0.0 1.0 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter RabGAP-TBC PF00566.18 EEQ38248.1 - 2.2e-37 128.8 0.0 4.1e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SSFA2_C PF14723.6 EEQ38248.1 - 0.22 11.4 2.3 11 5.9 0.1 2.5 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus PalH PF08733.10 EEQ38249.1 - 1e-80 271.2 23.0 1.3e-80 270.9 23.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF418 PF04235.12 EEQ38249.1 - 0.037 14.0 1.0 0.037 14.0 1.0 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF418) Inv-AAD PF18785.1 EEQ38250.1 - 2.1e-38 131.1 0.1 3.7e-38 130.3 0.1 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 EEQ38250.1 - 1.5e-32 112.9 0.1 2.3e-32 112.3 0.1 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 EEQ38250.1 - 5.9e-20 71.0 0.0 1.3e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEQ38250.1 - 7.6e-06 25.7 0.5 1.4e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 MafB19-like deaminase Auto_anti-p27 PF06677.12 EEQ38250.1 - 0.035 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.14 EEQ38250.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DUF3449 PF11931.8 EEQ38251.1 - 5.5e-59 199.1 0.7 5.5e-59 199.1 0.7 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EEQ38251.1 - 6e-12 45.9 4.4 8.7e-12 45.4 3.0 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 PRP9_N PF16958.5 EEQ38251.1 - 4.8e-11 42.9 7.2 4.8e-11 42.9 7.2 3.4 2 1 0 2 2 2 1 Pre-mRNA-splicing factor PRP9 N-terminus zf-met PF12874.7 EEQ38251.1 - 1.4e-10 41.2 5.5 3.2e-07 30.5 0.8 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEQ38251.1 - 8.4e-09 35.5 2.9 8.4e-09 35.5 2.9 3.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EEQ38251.1 - 0.00076 19.8 8.9 0.17 12.2 2.5 3.2 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 EEQ38251.1 - 0.0015 18.2 1.0 0.0035 17.1 1.0 1.6 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_4 PF13894.6 EEQ38251.1 - 0.04 14.7 3.2 1.1 10.2 0.6 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger Desulfoferrod_N PF06397.12 EEQ38251.1 - 0.084 12.5 0.3 0.17 11.5 0.3 1.4 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain C1_2 PF03107.16 EEQ38251.1 - 0.12 12.7 0.3 27 5.2 0.0 2.7 2 0 0 2 2 2 0 C1 domain Endonuclease_7 PF02945.15 EEQ38251.1 - 0.14 12.1 0.7 1.1 9.2 0.0 2.6 3 0 0 3 3 3 0 Recombination endonuclease VII Exo_endo_phos PF03372.23 EEQ38252.1 - 5.8e-06 26.0 0.0 9.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pox_MCEL PF03291.16 EEQ38253.1 - 4.6e-100 335.0 0.2 5.7e-100 334.7 0.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EEQ38253.1 - 2.9e-09 37.5 0.0 2.3e-05 25.0 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ38253.1 - 5.1e-08 33.6 0.0 3.1e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ38253.1 - 3e-05 24.6 0.0 0.47 11.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ38253.1 - 0.00014 21.8 0.0 0.00024 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ38253.1 - 0.00099 18.9 0.0 0.0034 17.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EEQ38253.1 - 0.092 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family TPMT PF05724.11 EEQ38253.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Vel1p PF10339.9 EEQ38253.1 - 0.21 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Yeast-specific zinc responsive FSH1 PF03959.13 EEQ38254.1 - 1.8e-58 197.7 0.0 2e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EEQ38254.1 - 0.002 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EEQ38254.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EEQ38254.1 - 0.03 14.1 0.2 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EEQ38254.1 - 0.1 12.2 0.0 9.8 5.7 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold Glyco_trans_4_5 PF16994.5 EEQ38254.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl-transferase family 4 Rit1_C PF17184.4 EEQ38255.1 - 1.9e-81 273.5 0.0 2.7e-81 273.0 0.0 1.3 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EEQ38255.1 - 1.2e-24 86.7 0.1 2.1e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain SPT2 PF08243.11 EEQ38256.1 - 3.1e-26 92.1 27.4 3.1e-26 92.1 27.4 2.9 3 1 0 3 3 3 1 SPT2 chromatin protein RNase_P_Rpp14 PF01900.19 EEQ38257.1 - 5.3e-35 119.8 0.0 6.6e-35 119.5 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family DUF5433 PF17498.2 EEQ38257.1 - 0.018 15.3 0.2 0.03 14.5 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5433) TPR_2 PF07719.17 EEQ38258.1 - 1.2e-20 71.9 18.5 0.0023 17.9 0.0 11.6 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ38258.1 - 5.2e-18 65.3 4.0 1.3e-08 35.2 0.0 8.0 7 2 4 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ38258.1 - 2.4e-15 55.6 17.3 0.038 13.8 0.1 10.6 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ38258.1 - 1.5e-14 52.9 13.0 0.0049 17.0 0.0 10.1 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ38258.1 - 1.3e-12 47.2 0.3 0.0015 18.1 0.0 6.3 6 0 0 6 6 6 2 TPR repeat TPR_12 PF13424.6 EEQ38258.1 - 4.6e-12 46.0 14.4 0.47 10.8 0.4 9.3 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ38258.1 - 3.1e-11 43.2 8.4 0.0035 17.9 0.0 10.2 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ38258.1 - 1.9e-10 40.6 9.7 2 9.4 0.1 10.1 10 2 2 12 12 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ38258.1 - 2.9e-08 33.2 8.5 3.3 7.9 0.0 8.4 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ38258.1 - 1.8e-06 28.4 4.1 0.75 10.5 0.0 5.9 7 1 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ38258.1 - 3.9e-05 23.8 14.9 0.06 13.6 0.3 7.0 5 2 3 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EEQ38258.1 - 8.5e-05 22.7 6.4 11 6.7 0.0 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ38258.1 - 0.00035 20.7 0.4 5.5 7.2 0.0 4.5 4 1 1 5 5 4 2 Tetratricopeptide repeat SPO22 PF08631.10 EEQ38258.1 - 0.0019 17.8 1.1 0.013 15.0 0.7 2.6 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like RPN7 PF10602.9 EEQ38258.1 - 0.0075 16.0 0.7 0.0075 16.0 0.7 4.0 4 1 0 4 4 4 1 26S proteasome subunit RPN7 TPR_4 PF07721.14 EEQ38258.1 - 0.029 15.0 0.0 58 4.7 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ38258.1 - 0.033 13.4 0.1 2.4 7.3 0.0 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ38258.1 - 0.038 13.9 0.3 1.9 8.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 EEQ38258.1 - 5.2 7.5 6.6 7.8 7.0 0.0 4.4 5 0 0 5 5 3 0 PPR repeat Glyco_transf_24 PF18404.1 EEQ38260.1 - 1.1e-137 457.8 2.3 1.1e-137 457.8 2.3 2.3 2 0 0 2 2 2 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EEQ38260.1 - 6e-33 114.9 5.2 2.7e-32 112.7 0.3 3.1 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EEQ38260.1 - 1.3e-29 103.4 0.0 3.2e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EEQ38260.1 - 6.1e-14 52.1 2.9 9.9e-14 51.4 0.4 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EEQ38260.1 - 1.9e-13 50.4 0.0 4.8e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EEQ38260.1 - 5.6e-07 29.4 2.6 1.6e-06 27.9 0.2 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 8 Thioredoxin_15 PF18403.1 EEQ38260.1 - 3.1e-05 24.0 1.3 0.00017 21.6 1.4 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain MTHFR PF02219.17 EEQ38261.1 - 4.8e-116 387.1 0.0 6.8e-116 386.6 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TLD PF07534.16 EEQ38262.1 - 1.9e-25 89.7 0.4 2.5e-25 89.3 0.4 1.1 1 0 0 1 1 1 1 TLD DUF4216 PF13952.6 EEQ38262.1 - 0.047 14.1 0.1 0.098 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4216) Asp_Glu_race PF01177.22 EEQ38263.1 - 1.3e-08 34.9 0.0 1.6e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Rad9 PF04139.13 EEQ38264.1 - 1.4e-14 54.2 0.7 1.7e-14 53.9 0.7 1.1 1 0 0 1 1 1 1 Rad9 MPC PF03650.13 EEQ38265.1 - 2.3e-38 130.7 0.1 2.5e-38 130.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Zn_clus PF00172.18 EEQ38266.1 - 6.4e-09 35.8 15.8 1.2e-08 34.9 15.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DJ-1_PfpI PF01965.24 EEQ38269.1 - 1.1e-13 51.3 0.0 3.2e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EEQ38269.1 - 3.7e-09 36.6 0.2 1.1e-08 35.0 0.2 1.9 1 1 0 1 1 1 1 ThiJ/PfpI family-like PocR PF10114.9 EEQ38269.1 - 0.082 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR Adaptin_N PF01602.20 EEQ38271.1 - 4.8e-90 302.6 16.2 9.2e-90 301.7 16.2 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEQ38271.1 - 5.9e-15 55.7 8.4 4.9e-13 49.4 1.2 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 EEQ38271.1 - 0.00063 19.0 1.0 0.26 10.3 0.1 2.8 2 1 0 2 2 2 2 RNAPII transcription regulator C-terminal HEAT PF02985.22 EEQ38271.1 - 0.0029 17.7 1.1 6.8 7.2 0.0 5.1 6 0 0 6 6 6 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EEQ38271.1 - 0.009 16.6 4.9 1.5 9.5 0.1 3.8 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region DBD_HTH PF18430.1 EEQ38271.1 - 0.0099 15.6 0.2 0.91 9.4 0.0 2.8 2 0 0 2 2 2 1 Putative DNA-binding domain HEAT_2 PF13646.6 EEQ38271.1 - 0.021 15.2 0.1 0.78 10.2 0.0 3.4 3 1 2 5 5 5 0 HEAT repeats MIF4G PF02854.19 EEQ38271.1 - 0.45 10.1 5.7 2.9 7.5 0.1 3.3 3 1 0 3 3 3 0 MIF4G domain SRP54_N PF02881.19 EEQ38271.1 - 0.63 10.3 3.2 6.2 7.1 0.1 2.9 3 0 0 3 3 3 0 SRP54-type protein, helical bundle domain FANCI_S2 PF14676.6 EEQ38271.1 - 1 9.7 4.7 0.51 10.6 0.6 2.7 3 2 0 3 3 3 0 FANCI solenoid 2 KxDL PF10241.9 EEQ38272.1 - 1.6e-08 34.7 6.4 1.6e-08 34.7 6.4 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein FAM76 PF16046.5 EEQ38272.1 - 1.1 8.6 8.5 1.2 8.4 8.5 1.1 1 0 0 1 1 1 0 FAM76 protein Metallopep PF12044.8 EEQ38273.1 - 2.4e-147 491.0 0.0 2.8e-147 490.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 EEQ38273.1 - 2.5e-05 24.5 0.7 7.3e-05 23.0 0.2 1.7 1 1 1 2 2 2 1 Metallo-peptidase family M12 Jacalin PF01419.17 EEQ38273.1 - 2.6e-05 24.2 0.1 5.5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_3 PF13582.6 EEQ38273.1 - 0.0006 20.3 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EEQ38273.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EEQ38273.1 - 0.062 12.3 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.6 EEQ38273.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Tyr-DNA_phospho PF06087.12 EEQ38274.1 - 3.8e-111 372.0 0.2 7.3e-111 371.1 0.2 1.4 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EEQ38274.1 - 0.0013 18.7 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 PLD-like domain SMC_N PF02463.19 EEQ38275.1 - 5.7e-62 209.0 30.0 1.3e-61 207.9 30.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEQ38275.1 - 6.9e-27 94.1 0.2 2.7e-26 92.2 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EEQ38275.1 - 1.6e-18 67.9 6.2 1.6e-18 67.9 6.2 6.4 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 EEQ38275.1 - 7.9e-18 65.3 4.7 5.5e-09 36.3 0.1 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEQ38275.1 - 9e-17 61.8 40.6 2.9e-16 60.2 13.6 4.8 2 2 2 4 4 4 2 AAA ATPase domain FliT PF05400.13 EEQ38275.1 - 0.0012 19.6 8.2 0.0012 19.6 8.2 8.4 7 2 2 9 9 9 1 Flagellar protein FliT BRCT PF00533.26 EEQ38275.1 - 0.015 15.7 0.4 0.24 11.8 0.0 3.3 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain AAA_29 PF13555.6 EEQ38275.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain FA_desaturase PF00487.24 EEQ38276.1 - 8.3e-30 104.5 23.0 1.1e-29 104.0 23.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EEQ38276.1 - 5.7e-11 42.4 0.0 1.2e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUFIP1 PF10453.9 EEQ38277.1 - 1.2e-19 69.9 7.9 2.1e-19 69.1 7.9 1.4 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.24 EEQ38277.1 - 1.3e-06 28.1 2.7 2e-06 27.6 2.7 1.2 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EEQ38277.1 - 1e-05 25.2 3.0 1.5e-05 24.7 3.0 1.2 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EEQ38277.1 - 1.1e-05 25.3 8.5 1.7e-05 24.7 8.5 1.3 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EEQ38277.1 - 0.0006 20.5 0.8 0.001 19.8 0.8 1.4 1 0 0 1 1 1 1 Torus domain ANAPC_CDC26 PF10471.9 EEQ38277.1 - 0.0021 18.8 0.2 0.0048 17.7 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 zf-CCCH_2 PF14608.6 EEQ38277.1 - 2 9.0 6.6 3.5 8.3 6.6 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger tRNA-synt_2b PF00587.25 EEQ38278.1 - 5e-34 117.8 0.0 9.8e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EEQ38278.1 - 5.8e-23 81.2 4.2 5.8e-23 81.2 4.2 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF3698 PF12479.8 EEQ38278.1 - 0.0054 17.2 0.0 0.022 15.3 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3698) OmpH PF03938.14 EEQ38278.1 - 0.012 16.0 3.2 0.028 14.8 3.2 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 EEQ38278.1 - 0.068 13.6 2.2 0.12 12.8 1.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 EEQ38278.1 - 0.2 12.3 2.5 0.49 11.1 2.5 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) GED PF02212.18 EEQ38278.1 - 0.22 11.7 3.1 0.36 11.0 2.4 1.7 1 1 0 1 1 1 0 Dynamin GTPase effector domain HrpB2 PF09487.10 EEQ38278.1 - 0.29 11.6 2.0 0.52 10.8 0.9 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB2) FlaG PF03646.15 EEQ38278.1 - 0.48 10.6 6.0 1.5 9.1 5.6 2.0 1 1 1 2 2 2 0 FlaG protein WD40 PF00400.32 EEQ38279.1 - 1.7e-19 69.8 5.7 0.00055 20.7 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38279.1 - 5.2e-08 33.1 0.1 0.038 14.3 0.0 4.6 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ38279.1 - 0.0011 17.7 0.4 3.7 6.1 0.0 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Cytokin_check_N PF10407.9 EEQ38280.1 - 1.5e-25 88.9 0.2 3.3e-25 87.8 0.2 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus Ribonuclease_3 PF00636.26 EEQ38281.1 - 0.00026 21.6 0.0 0.00058 20.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain DAO PF01266.24 EEQ38282.1 - 2.5e-29 103.0 0.0 2.9e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EEQ38282.1 - 0.00045 19.5 0.4 0.00045 19.5 0.4 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EEQ38282.1 - 0.0027 17.0 0.0 0.11 11.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ38282.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EEQ38282.1 - 0.022 13.9 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 EEQ38282.1 - 0.026 14.7 0.3 0.07 13.4 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amidase PF01425.21 EEQ38283.1 - 6.6e-95 318.7 0.0 9.4e-95 318.2 0.0 1.2 1 0 0 1 1 1 1 Amidase HhH-GPD PF00730.25 EEQ38285.1 - 4.4e-10 40.0 0.0 7.5e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Transthyretin PF00576.21 EEQ38288.1 - 3.7e-34 117.7 0.0 4.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family Stn1 PF10451.9 EEQ38289.1 - 4.5e-09 35.6 0.4 1e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Telomere regulation protein Stn1 DUF1041 PF06292.17 EEQ38289.1 - 0.027 14.9 0.6 0.063 13.7 0.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) UPF0302 PF08864.10 EEQ38289.1 - 0.11 12.5 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 UPF0302 domain Methyltransf_8 PF05148.15 EEQ38290.1 - 4.3e-63 213.1 8.3 1.7e-30 106.5 0.0 3.6 2 1 1 3 3 3 3 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EEQ38290.1 - 1.7e-06 28.6 0.1 9.5e-06 26.2 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ38290.1 - 0.00013 22.6 0.0 0.007 17.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ38290.1 - 0.0017 18.2 0.2 0.016 15.0 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ38290.1 - 0.027 14.0 0.0 0.41 10.2 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase small domain FAM220 PF15487.6 EEQ38290.1 - 1.1 8.9 12.5 0.048 13.3 6.5 1.7 2 0 0 2 2 2 0 FAM220 family CPSF100_C PF13299.6 EEQ38290.1 - 5.3 7.2 11.9 0.91 9.7 6.0 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EEQ38290.1 - 6.6 5.8 7.3 28 3.8 4.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter ANAPC4_WD40 PF12894.7 EEQ38291.1 - 3.9e-07 30.3 0.3 3.3e-05 24.1 0.1 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ38291.1 - 1.3e-06 29.0 12.3 0.017 15.9 0.0 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Peptidase_C14 PF00656.22 EEQ38291.1 - 0.024 14.6 0.3 0.045 13.7 0.3 1.4 1 0 0 1 1 1 0 Caspase domain HECT PF00632.25 EEQ38292.1 - 7.5e-96 321.2 0.0 1e-95 320.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EEQ38292.1 - 4.9e-33 112.9 23.3 4.4e-12 45.9 2.1 4.0 4 0 0 4 4 4 3 WW domain C2 PF00168.30 EEQ38292.1 - 1e-19 70.7 0.1 2.7e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.25 EEQ38294.1 - 4.1e-26 91.9 0.0 5.3e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38294.1 - 1e-12 47.9 0.0 1.4e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ38294.1 - 1.5e-09 37.1 0.0 2e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EEQ38294.1 - 0.00075 19.5 0.0 0.36 10.7 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family LRR_8 PF13855.6 EEQ38295.1 - 9.9e-17 60.5 55.4 5e-06 26.2 8.8 8.3 8 2 2 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 EEQ38295.1 - 6e-14 51.9 73.5 0.0016 18.8 0.9 11.0 8 3 5 13 13 13 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EEQ38295.1 - 3.4e-11 42.3 40.6 0.38 10.9 0.6 13.0 13 0 0 13 13 13 4 Leucine Rich repeat LRR_9 PF14580.6 EEQ38295.1 - 8.1e-08 32.0 16.5 0.059 12.9 1.1 5.0 3 2 2 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 EEQ38295.1 - 4.6e-05 23.4 48.1 2.1 9.2 0.2 13.0 12 2 1 13 13 13 4 Leucine Rich Repeat LRR_5 PF13306.6 EEQ38295.1 - 0.0025 17.8 7.8 6 6.9 0.0 4.9 2 2 2 5 5 5 3 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EEQ38295.1 - 0.055 13.6 37.3 1.6 9.0 0.3 9.0 7 1 0 7 7 7 0 FNIP Repeat MRG PF05712.13 EEQ38296.1 - 6.1e-38 130.1 0.1 1e-37 129.4 0.1 1.3 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EEQ38296.1 - 5.4e-08 32.6 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain LCD1 PF09798.9 EEQ38296.1 - 0.018 13.6 1.6 0.024 13.2 1.6 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein RGI1 PF10843.8 EEQ38297.1 - 3.4e-110 366.2 6.1 3.9e-110 366.0 6.1 1.0 1 0 0 1 1 1 1 Respiratory growth induced protein 1 CaMKII_AD PF08332.10 EEQ38297.1 - 0.0075 16.4 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain Tim17 PF02466.19 EEQ38298.1 - 1.2e-36 125.5 5.2 1.7e-36 124.9 5.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ERbeta_N PF12497.8 EEQ38298.1 - 0.079 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Estrogen receptor beta DUF1978 PF09321.10 EEQ38299.1 - 0.0014 18.0 1.3 0.0019 17.6 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1978) ZYG-11_interact PF05884.12 EEQ38299.1 - 0.012 15.1 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 PKK PF12474.8 EEQ38299.1 - 0.23 11.6 8.4 0.36 10.9 8.4 1.2 1 0 0 1 1 1 0 Polo kinase kinase Mitofilin PF09731.9 EEQ38299.1 - 0.25 10.1 6.6 0.38 9.5 6.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Helo_like_N PF17111.5 EEQ38299.1 - 0.52 9.6 4.1 1.1 8.5 4.1 1.5 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Chitin_synth_2 PF03142.15 EEQ38300.1 - 1.9e-08 33.4 6.9 0.00067 18.4 0.5 2.2 2 0 0 2 2 2 2 Chitin synthase DUF996 PF06195.13 EEQ38300.1 - 0.012 15.9 0.1 0.012 15.9 0.1 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF996) CCSMST1 PF15013.6 EEQ38300.1 - 0.073 13.2 3.4 2.6 8.3 0.1 3.3 3 0 0 3 3 3 0 CCSMST1 family Chitin_synth_1 PF01644.17 EEQ38301.1 - 1.1e-72 243.3 0.9 1.5e-72 242.9 0.9 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EEQ38301.1 - 7.5e-13 48.2 0.1 1.4e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EEQ38301.1 - 3.5e-10 39.1 0.0 2.4e-09 36.4 0.0 2.1 1 1 0 2 2 2 1 Chitin synthase Glycos_transf_2 PF00535.26 EEQ38301.1 - 0.0021 17.9 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 2 A_deaminase PF00962.22 EEQ38303.1 - 2.2e-67 227.7 0.0 2.6e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase GTSE1_N PF15259.6 EEQ38303.1 - 0.2 11.8 0.1 0.56 10.4 0.1 1.6 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 PET10 PF17316.2 EEQ38304.1 - 0.0016 18.0 1.2 0.0024 17.4 1.2 1.2 1 0 0 1 1 1 1 Petite colonies protein 10 YtxH PF12732.7 EEQ38304.1 - 0.084 13.4 0.0 0.62 10.6 0.0 2.2 2 0 0 2 2 2 0 YtxH-like protein Bap31_Bap29_C PF18035.1 EEQ38304.1 - 0.24 11.4 3.9 13 5.9 1.3 2.6 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain GatB_N PF02934.15 EEQ38305.1 - 7e-91 304.4 0.0 9e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EEQ38305.1 - 4.7e-31 107.7 1.2 8.3e-31 106.9 1.2 1.4 1 0 0 1 1 1 1 GatB domain ComX PF05952.12 EEQ38305.1 - 0.17 11.8 0.2 13 5.8 0.0 3.1 4 0 0 4 4 4 0 Bacillus competence pheromone ComX STE3 PF02076.15 EEQ38306.1 - 1.5e-73 247.6 21.5 1.8e-73 247.3 21.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF485 PF04341.12 EEQ38306.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF485 DUF3989 PF13150.6 EEQ38306.1 - 0.97 9.2 4.9 9.1 6.1 1.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3989) DUF4131 PF13567.6 EEQ38306.1 - 1.5 8.5 6.5 0.83 9.3 1.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) HEAT_EZ PF13513.6 EEQ38307.1 - 1.5e-18 66.9 6.0 2.6e-08 34.2 0.1 8.9 8 1 1 9 9 9 3 HEAT-like repeat HEAT PF02985.22 EEQ38307.1 - 3.9e-12 45.3 13.4 0.0062 16.7 0.0 10.4 14 0 0 14 14 10 4 HEAT repeat HEAT_2 PF13646.6 EEQ38307.1 - 7.5e-12 45.5 0.9 0.011 16.1 0.0 7.0 4 3 4 9 9 8 4 HEAT repeats IBN_N PF03810.19 EEQ38307.1 - 1.2e-11 44.3 6.7 1.9e-09 37.3 0.6 4.8 4 1 1 5 5 4 1 Importin-beta N-terminal domain RIX1 PF08167.12 EEQ38307.1 - 1.9e-10 40.8 1.4 0.001 18.8 0.0 6.2 5 2 1 6 6 6 2 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 EEQ38307.1 - 5.7e-08 33.0 0.6 0.065 13.3 0.0 5.1 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EEQ38307.1 - 1.1e-06 28.9 1.7 0.069 13.3 0.4 5.1 3 2 2 5 5 5 1 Parkin co-regulated protein DUF3385 PF11865.8 EEQ38307.1 - 9.5e-06 25.6 8.1 1.3 8.9 0.0 6.4 4 2 1 6 6 6 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 EEQ38307.1 - 4.2e-05 24.1 5.1 2.5 8.8 0.3 6.4 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EEQ38307.1 - 0.00043 20.4 2.7 9.3 6.5 0.0 4.9 5 1 0 5 5 4 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EEQ38307.1 - 0.0054 16.3 0.1 5.1 6.6 0.0 4.1 3 0 0 3 3 3 1 CLASP N terminal FliH PF02108.16 EEQ38307.1 - 0.025 14.6 0.6 0.77 9.8 0.1 3.4 3 0 0 3 3 3 0 Flagellar assembly protein FliH MMS19_C PF12460.8 EEQ38307.1 - 0.051 12.7 15.8 0.93 8.5 0.2 5.2 3 2 2 5 5 5 0 RNAPII transcription regulator C-terminal Sars6 PF12133.8 EEQ38307.1 - 0.32 10.9 3.0 16 5.5 0.1 3.9 4 0 0 4 4 4 0 Open reading frame 6 from SARS coronavirus Xpo1 PF08389.12 EEQ38307.1 - 0.5 10.4 22.8 0.42 10.7 1.9 6.2 6 1 0 6 6 6 0 Exportin 1-like protein DEAD PF00270.29 EEQ38308.1 - 1.1e-44 152.2 1.0 2e-44 151.4 1.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ38308.1 - 2.5e-31 108.3 0.2 2.4e-30 105.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EEQ38308.1 - 0.00043 20.0 0.1 0.00097 18.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EEQ38308.1 - 0.00063 19.8 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EEQ38308.1 - 0.0022 18.3 0.2 0.0041 17.5 0.2 1.5 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EEQ38308.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.5 1 1 0 1 1 1 0 Helicase AAA_22 PF13401.6 EEQ38308.1 - 0.02 15.2 1.1 0.13 12.6 1.1 2.2 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EEQ38309.1 - 5.3e-12 45.9 0.2 2e-10 40.8 0.0 2.0 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family Nucleoporin_N PF08801.11 EEQ38310.1 - 1.9e-131 438.8 14.8 2.5e-131 438.4 14.8 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EEQ38310.1 - 2.1e-111 373.5 5.4 8.8e-111 371.5 5.4 1.9 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Peptidase_M28 PF04389.17 EEQ38311.1 - 1e-24 87.3 0.0 1.5e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEQ38311.1 - 0.0019 17.9 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 SSB PF00436.25 EEQ38312.1 - 1.9e-14 53.6 0.1 2.3e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Single-strand binding protein family PPP4R2 PF09184.11 EEQ38313.1 - 0.02 14.5 8.7 0.028 14.0 8.7 1.3 1 0 0 1 1 1 0 PPP4R2 Paf1 PF03985.13 EEQ38313.1 - 0.025 13.6 8.4 0.036 13.1 8.4 1.3 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.14 EEQ38313.1 - 0.16 10.2 6.4 0.17 10.1 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 EEQ38313.1 - 0.52 8.8 13.7 0.68 8.5 13.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.11 EEQ38313.1 - 3.4 6.1 7.2 4.1 5.8 7.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Pox_Ag35 PF03286.14 EEQ38313.1 - 4.2 7.1 9.0 7.4 6.3 9.0 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 EEQ38313.1 - 4.9 6.5 15.2 7.3 5.9 15.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3844 PF12955.7 EEQ38314.1 - 2.9e-28 98.1 5.1 5e-28 97.3 5.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) Evr1_Alr PF04777.13 EEQ38315.1 - 1.1e-26 93.2 0.1 1.9e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC4 PF18775.1 EEQ38315.1 - 0.04 14.1 0.1 0.08 13.1 0.1 1.5 1 0 0 1 1 1 0 APOBEC4 DUF2691 PF10903.8 EEQ38315.1 - 0.052 13.4 0.0 0.081 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2691) SNAD4 PF18750.1 EEQ38315.1 - 0.06 13.5 0.0 0.086 13.0 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 EEQ38315.1 - 0.075 13.3 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 APOBEC1 NAD1 PF18778.1 EEQ38315.1 - 0.098 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 G-gamma PF00631.22 EEQ38316.1 - 1.3e-14 54.0 0.3 1.6e-14 53.6 0.3 1.1 1 0 0 1 1 1 1 GGL domain V-SNARE_C PF12352.8 EEQ38317.1 - 2.2e-13 50.2 0.6 2.2e-13 50.2 0.6 2.6 3 1 1 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus MCU PF04678.13 EEQ38317.1 - 0.067 13.3 3.2 1.2 9.2 3.2 2.2 1 1 0 1 1 1 0 Mitochondrial calcium uniporter SERTA PF06031.13 EEQ38317.1 - 0.32 10.7 3.2 2.1 8.1 0.1 3.3 3 0 0 3 3 3 0 SERTA motif DUF1691 PF07950.11 EEQ38318.1 - 8.6e-19 68.3 0.2 5.7e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) NifU_N PF01592.16 EEQ38319.1 - 2.7e-59 198.9 0.2 3.4e-59 198.6 0.2 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 EEQ38319.1 - 0.014 15.6 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 TSCPD domain DUF4855 PF16147.5 EEQ38320.1 - 0.17 10.9 0.0 0.39 9.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4855) Ribosomal_L5e PF17144.4 EEQ38321.1 - 4.3e-80 267.4 0.7 6.3e-80 266.9 0.0 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EEQ38321.1 - 1.9e-32 112.0 11.7 1.9e-32 112.0 11.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 EEQ38321.1 - 0.00056 20.1 0.9 0.14 12.4 0.0 3.0 2 1 1 3 3 3 2 Threonine synthase N terminus Ribosomal_L18p PF00861.22 EEQ38321.1 - 0.0009 19.6 1.1 0.0025 18.2 0.0 2.0 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast DUF1160 PF06648.11 EEQ38321.1 - 0.0094 15.9 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1160) NAC PF01849.18 EEQ38321.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 NAC domain MTP18 PF10558.9 EEQ38322.1 - 7.5e-73 244.1 0.6 8.8e-73 243.9 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) 3-HAO PF06052.12 EEQ38323.1 - 4.7e-68 227.6 0.1 5.3e-68 227.4 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EEQ38323.1 - 2.9e-06 26.9 0.1 4.3e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 EEQ38323.1 - 0.0066 16.4 1.8 0.01 15.9 0.5 1.9 2 1 0 2 2 2 1 Double zinc ribbon Cupin_1 PF00190.22 EEQ38323.1 - 0.099 12.2 0.1 0.15 11.7 0.1 1.2 1 0 0 1 1 1 0 Cupin Rpr2 PF04032.16 EEQ38323.1 - 0.34 11.2 2.1 0.69 10.2 0.1 2.1 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_10 PF10058.9 EEQ38323.1 - 1 9.1 4.6 2.4 7.9 0.5 2.8 2 1 1 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein ADK_lid PF05191.14 EEQ38323.1 - 1.5 8.9 6.6 12 5.9 0.2 2.9 3 0 0 3 3 3 0 Adenylate kinase, active site lid DUF2407_C PF13373.6 EEQ38324.1 - 4.9e-39 133.7 0.0 8.2e-39 133.0 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EEQ38324.1 - 5.1e-21 75.2 0.0 1.1e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EEQ38324.1 - 0.0043 16.8 0.0 0.0085 15.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family PAP2 PF01569.21 EEQ38324.1 - 0.087 12.6 0.3 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 PAP2 superfamily Mito_carr PF00153.27 EEQ38325.1 - 2.6e-59 197.1 2.3 7.4e-22 77.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1741 PF08427.10 EEQ38326.1 - 1.8e-08 34.3 0.3 8.5e-08 32.1 0.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) DPPIV_N PF00930.21 EEQ38327.1 - 9.5e-58 195.6 1.2 1.7e-57 194.8 1.2 1.4 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EEQ38327.1 - 2.4e-43 148.1 0.4 3.8e-43 147.4 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EEQ38327.1 - 2.8e-06 27.1 0.0 5.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EEQ38327.1 - 0.062 13.9 0.0 1 9.9 0.0 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family Noc2 PF03715.13 EEQ38328.1 - 2.1e-128 427.8 3.3 3.6e-128 427.0 3.3 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 EEQ38328.1 - 2.9e-05 22.5 0.1 2.9e-05 22.5 0.1 3.1 2 1 1 3 3 3 2 Nop14-like family Zn_clus PF00172.18 EEQ38329.1 - 1.9e-05 24.7 6.0 4.3e-05 23.5 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EEQ38329.1 - 0.12 12.4 0.1 0.59 10.2 0.0 2.1 2 0 0 2 2 2 0 PAS fold zf-RING_2 PF13639.6 EEQ38330.1 - 1.4e-09 38.2 7.7 3.1e-09 37.0 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ38330.1 - 3e-07 30.2 7.0 7.2e-07 29.0 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ38330.1 - 1.2e-06 28.2 3.3 1.2e-06 28.2 3.3 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EEQ38330.1 - 1.9e-06 27.6 8.3 4.5e-06 26.4 8.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ38330.1 - 1.5e-05 25.2 9.9 9.1e-05 22.7 9.9 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EEQ38330.1 - 5.8e-05 23.0 5.8 0.00013 21.8 5.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEQ38330.1 - 0.00013 21.8 4.6 0.00028 20.7 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ38330.1 - 0.00016 21.6 8.7 0.00048 20.1 2.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EEQ38330.1 - 0.0018 18.3 2.5 0.0037 17.3 2.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EEQ38330.1 - 0.02 14.7 4.7 0.02 14.7 4.7 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EEQ38330.1 - 0.024 14.3 4.8 0.067 12.8 4.8 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 EEQ38330.1 - 0.031 14.3 5.6 0.098 12.7 5.6 2.0 1 1 0 1 1 1 0 Zinc-finger Glutaredoxin PF00462.24 EEQ38330.1 - 0.07 13.4 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin zf-Nse PF11789.8 EEQ38330.1 - 0.23 11.3 3.0 0.6 10.0 3.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 EEQ38330.1 - 0.25 11.3 1.2 2.2 8.3 0.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 EEQ38330.1 - 0.89 9.8 6.7 4.2 7.6 6.7 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EEQ38330.1 - 1.3 9.2 6.4 3.1 8.0 6.4 1.7 1 0 0 1 1 1 0 RING-variant domain C2 PF00168.30 EEQ38331.1 - 4.8e-65 216.3 6.1 2.3e-18 66.4 0.1 4.5 4 0 0 4 4 4 4 C2 domain RNA_pol_Rpc4 PF05132.14 EEQ38331.1 - 0.0015 18.9 4.1 0.0052 17.2 4.1 1.8 1 0 0 1 1 1 1 RNA polymerase III RPC4 Connexin PF00029.19 EEQ38331.1 - 0.0019 18.0 2.3 0.0019 18.0 2.3 1.7 2 0 0 2 2 2 1 Connexin CDC45 PF02724.14 EEQ38331.1 - 0.016 13.6 11.6 0.023 13.0 11.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SMP_LBD PF17047.5 EEQ38331.1 - 0.031 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain TRAP_alpha PF03896.16 EEQ38331.1 - 0.032 13.5 4.0 0.069 12.3 4.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SpoIIP PF07454.11 EEQ38331.1 - 0.05 13.0 6.7 0.097 12.1 6.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 EEQ38331.1 - 0.056 12.2 4.7 0.092 11.5 4.7 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3810 PF12725.7 EEQ38331.1 - 0.064 12.6 0.7 0.12 11.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) RR_TM4-6 PF06459.12 EEQ38331.1 - 0.068 13.0 8.4 0.15 11.9 8.4 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 EEQ38331.1 - 0.12 10.9 9.5 0.18 10.3 9.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Tim54 PF11711.8 EEQ38331.1 - 0.15 10.8 8.2 0.33 9.7 8.2 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.10 EEQ38331.1 - 0.41 11.0 14.9 1.2 9.4 14.9 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4746 PF15928.5 EEQ38331.1 - 0.69 9.3 12.0 1.5 8.2 12.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 EEQ38331.1 - 0.77 8.5 6.4 1.4 7.6 6.4 1.3 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 EEQ38331.1 - 0.78 9.9 6.7 2 8.6 6.7 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PPL5 PF18168.1 EEQ38331.1 - 0.79 9.0 6.3 1.7 7.9 6.3 1.5 1 0 0 1 1 1 0 Prim-pol family 5 DUF1764 PF08576.10 EEQ38331.1 - 0.99 10.3 13.9 5.2 8.0 13.9 2.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Zip PF02535.22 EEQ38331.1 - 1.1 8.4 2.7 2.1 7.5 2.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter LRRC37AB_C PF14914.6 EEQ38331.1 - 1.6 8.6 4.9 4.4 7.2 4.9 1.7 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain KRTAP PF11759.8 EEQ38331.1 - 2 9.0 6.5 4 8.0 6.5 1.4 1 0 0 1 1 1 0 Keratin-associated matrix V_ATPase_I PF01496.19 EEQ38331.1 - 5.4 4.8 6.6 8.2 4.2 6.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rpb2_6 PF00562.28 EEQ38332.1 - 1.7e-124 415.9 0.1 1.7e-124 415.9 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EEQ38332.1 - 1.1e-58 198.2 0.7 1.5e-58 197.6 0.7 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EEQ38332.1 - 9.5e-40 136.3 2.0 1.9e-39 135.3 1.8 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EEQ38332.1 - 2.2e-34 117.7 0.2 6.8e-34 116.1 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EEQ38332.1 - 1.5e-25 89.2 0.4 5.5e-25 87.4 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EEQ38332.1 - 2.8e-18 65.9 0.0 6e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EEQ38332.1 - 4.5e-13 49.5 0.3 1.1e-12 48.3 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Ribonuc_red_lgC PF02867.15 EEQ38333.1 - 4.3e-181 603.0 0.0 6e-181 602.5 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EEQ38333.1 - 2.2e-18 66.0 0.1 6.3e-18 64.6 0.0 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain Tfb2 PF03849.14 EEQ38334.1 - 8.9e-141 469.0 0.1 1.1e-140 468.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EEQ38334.1 - 3.1e-23 81.9 0.4 6.8e-23 80.9 0.4 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EEQ38334.1 - 0.00017 21.8 0.0 0.00036 20.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Response_reg PF00072.24 EEQ38335.1 - 8.4e-10 38.8 0.0 1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain GTP1_OBG PF01018.22 EEQ38336.1 - 6.6e-38 129.7 0.9 6.3e-27 94.1 1.0 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EEQ38336.1 - 1.2e-21 76.9 0.0 2.2e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ38336.1 - 1.1e-08 34.8 0.0 1.6e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EEQ38336.1 - 0.00013 21.4 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EEQ38336.1 - 0.019 15.0 0.2 5.4 7.1 0.0 2.6 2 1 1 3 3 3 0 Dynamin family Ras PF00071.22 EEQ38336.1 - 0.12 11.9 0.0 0.4 10.3 0.0 1.8 2 0 0 2 2 2 0 Ras family Helicase_C PF00271.31 EEQ38337.1 - 3.1e-31 108.0 0.1 1.8e-30 105.5 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ38337.1 - 2.1e-20 73.2 0.2 5.3e-20 71.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF202 PF02656.15 EEQ38338.1 - 2.9e-15 56.5 1.2 9.1e-15 54.9 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) COX1 PF00115.20 EEQ38338.1 - 0.0044 15.9 0.1 0.0051 15.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I TFIIB PF00382.19 EEQ38339.1 - 1.1e-16 60.7 0.1 2.7e-16 59.4 0.1 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat MUG113 PF13455.6 EEQ38339.1 - 0.001 19.7 0.0 0.002 18.7 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Neur_chan_memb PF02932.16 EEQ38339.1 - 3 7.9 4.4 3.8 7.5 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SDA1 PF05285.12 EEQ38341.1 - 4.9e-45 154.5 24.0 5.9e-45 154.2 24.0 1.0 1 0 0 1 1 1 1 SDA1 GTP-bdg_N PF13167.6 EEQ38341.1 - 0.29 11.8 2.2 2 9.1 2.2 2.2 1 1 0 1 1 1 0 GTP-binding GTPase N-terminal HMG_box PF00505.19 EEQ38342.1 - 2.2e-09 37.6 5.8 2.2e-09 37.6 5.8 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EEQ38342.1 - 3.7e-05 24.2 4.3 3.7e-05 24.2 4.3 2.0 2 0 0 2 2 2 1 HMG-box domain Acyl_transf_1 PF00698.21 EEQ38343.1 - 4.2e-11 42.9 0.0 5.3e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain FTHFS PF01268.19 EEQ38344.1 - 2.3e-202 673.1 0.5 3.2e-202 672.6 0.5 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EEQ38344.1 - 5.5e-62 207.8 1.1 1.4e-61 206.4 0.3 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EEQ38344.1 - 4.2e-38 130.2 1.5 8.6e-38 129.2 1.5 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain CbiA PF01656.23 EEQ38344.1 - 0.028 14.5 0.0 0.13 12.4 0.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AdoHcyase_NAD PF00670.21 EEQ38344.1 - 0.12 12.5 0.4 4.1 7.4 0.1 3.1 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GTP_EFTU PF00009.27 EEQ38344.1 - 0.16 11.5 0.2 0.37 10.3 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Rhodanese PF00581.20 EEQ38345.1 - 1e-17 64.5 0.0 1.4e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain VHP PF02209.19 EEQ38345.1 - 0.092 12.8 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Villin headpiece domain RRP36 PF06102.12 EEQ38346.1 - 5.8e-44 150.0 24.7 5.8e-44 150.0 24.7 2.1 1 1 1 2 2 2 1 rRNA biogenesis protein RRP36 Sporozoite_P67 PF05642.11 EEQ38346.1 - 4.8 5.2 9.7 6.8 4.6 9.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATP-grasp_2 PF08442.10 EEQ38347.1 - 2.9e-71 239.2 0.9 3.8e-71 238.8 0.3 1.5 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EEQ38347.1 - 6.6e-25 87.7 0.1 1.8e-24 86.3 0.1 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EEQ38347.1 - 2.4e-09 37.0 0.2 6.9e-09 35.5 0.2 1.8 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EEQ38347.1 - 0.0016 18.3 0.2 0.0068 16.2 0.1 2.1 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Big_6 PF17936.1 EEQ38348.1 - 0.082 13.2 1.1 3.4 8.0 0.2 2.2 2 0 0 2 2 2 0 Bacterial Ig domain COQ7 PF03232.13 EEQ38348.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Proteasome PF00227.26 EEQ38349.1 - 1.3e-54 184.6 0.1 1.7e-54 184.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ38349.1 - 2.2e-12 46.4 0.0 5.1e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 EEQ38350.1 - 1.1e-36 127.1 0.1 3.4e-36 125.4 0.1 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EEQ38350.1 - 2.5e-18 66.6 6.0 2.5e-18 66.6 6.0 2.1 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal ATG7_N PF16420.5 EEQ38351.1 - 2.2e-58 198.3 1.4 3.5e-58 197.6 1.4 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EEQ38351.1 - 2e-40 138.7 0.0 3.2e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EEQ38351.1 - 0.014 15.5 0.0 0.078 13.0 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4852 PF16144.5 EEQ38351.1 - 5.1 7.3 6.5 25 5.0 0.4 3.5 2 1 0 3 3 3 0 Domain of unknown function (DUF4852) NMD3 PF04981.13 EEQ38352.1 - 3.8e-83 278.7 2.2 6.4e-83 277.9 2.2 1.4 1 0 0 1 1 1 1 NMD3 family FYVE PF01363.21 EEQ38352.1 - 0.043 14.0 0.9 1.6 8.9 0.1 2.7 2 0 0 2 2 2 0 FYVE zinc finger VPS11_C PF12451.8 EEQ38352.1 - 0.1 12.8 4.3 0.21 11.8 4.3 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal MFAP1 PF06991.11 EEQ38352.1 - 0.13 12.1 10.5 0.21 11.4 10.5 1.2 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing HypA PF01155.19 EEQ38352.1 - 0.67 10.0 5.6 4.2 7.4 0.1 2.5 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EEQ38352.1 - 1.1 9.3 6.7 50 4.0 6.7 2.8 1 1 0 1 1 1 0 Double zinc ribbon CpXC PF14353.6 EEQ38352.1 - 1.9 8.6 5.3 5.6 7.0 0.1 3.1 3 0 0 3 3 3 0 CpXC protein FYDLN_acid PF09538.10 EEQ38352.1 - 8.2 7.2 11.2 36 5.1 8.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Bromodomain PF00439.25 EEQ38353.1 - 2e-25 88.7 0.7 4.3e-25 87.6 0.7 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EEQ38353.1 - 9.4e-09 35.5 0.0 1.9e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ38353.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ38353.1 - 0.00086 19.7 0.1 0.0016 18.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Raftlin PF15250.6 EEQ38353.1 - 0.81 8.4 5.7 1.3 7.7 5.7 1.3 1 0 0 1 1 1 0 Raftlin CDC45 PF02724.14 EEQ38353.1 - 7.3 4.7 21.2 11 4.2 21.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EEQ38353.1 - 10 4.2 39.6 14 3.7 39.6 1.1 1 0 0 1 1 1 0 Nop14-like family Glucosamine_iso PF01182.20 EEQ38354.1 - 4.5e-64 216.4 0.0 5.2e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CPDase PF07823.11 EEQ38355.1 - 6.1e-54 182.8 0.8 1.4e-52 178.3 0.8 2.0 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 EEQ38355.1 - 0.00083 19.3 0.2 1.7 8.6 0.0 2.3 2 1 0 2 2 2 2 2'-5' RNA ligase superfamily HORMA PF02301.18 EEQ38356.1 - 2.3e-22 79.6 1.5 7.5e-22 78.0 1.5 1.7 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 EEQ38356.1 - 0.00011 22.3 1.1 0.00039 20.4 1.1 1.7 1 1 0 1 1 1 1 Autophagy-related protein 101 bacHORMA_2 PF18173.1 EEQ38356.1 - 0.0054 16.6 0.1 0.0099 15.7 0.1 1.6 1 0 0 1 1 1 1 Bacterial HORMA domain 2 Arcadin_1 PF18653.1 EEQ38356.1 - 0.0062 16.6 1.0 2.6 8.1 0.0 2.2 1 1 1 2 2 2 2 Arcadin 1 MethyltransfD12 PF02086.15 EEQ38356.1 - 0.036 13.8 0.2 0.042 13.5 0.2 1.1 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase Cyclin_N PF00134.23 EEQ38358.1 - 9.3e-10 38.3 0.2 2.3e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Porin_3 PF01459.22 EEQ38359.1 - 1.7e-72 244.2 5.9 1.9e-72 244.0 5.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin Hexapep_loop PF18776.1 EEQ38359.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Hexapeptide repeat including loop Macro_2 PF14519.6 EEQ38360.1 - 2.4e-12 46.8 0.0 5.5e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 Macro-like domain Macro PF01661.21 EEQ38360.1 - 0.011 15.8 0.0 0.16 12.0 0.0 2.1 1 1 1 2 2 2 0 Macro domain NUDIX PF00293.28 EEQ38361.1 - 1.4e-10 41.4 0.0 1.8e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain BOP1NT PF08145.12 EEQ38363.1 - 4.5e-107 357.8 5.7 1.1e-106 356.5 5.7 1.7 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EEQ38363.1 - 6e-26 90.2 3.3 3e-09 37.4 0.1 6.1 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38363.1 - 3e-08 33.8 0.1 0.028 14.7 0.0 5.4 3 3 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Reg_prop PF07494.11 EEQ38363.1 - 0.16 12.3 0.0 0.46 10.9 0.0 1.8 1 0 0 1 1 1 0 Two component regulator propeller RRM_1 PF00076.22 EEQ38364.1 - 1.8e-19 69.3 0.0 3.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ38364.1 - 0.00052 19.6 0.0 0.00087 18.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EEQ38364.1 - 0.013 15.5 0.0 0.032 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif RRM_7 PF16367.5 EEQ38364.1 - 0.036 14.2 0.0 0.092 12.9 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif Acyltransferase PF01553.21 EEQ38365.1 - 0.00067 19.3 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Histone_H2A_C PF16211.5 EEQ38366.1 - 8.8e-20 70.1 1.1 1.5e-19 69.4 1.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EEQ38366.1 - 6.8e-17 62.1 0.0 8.9e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEQ38366.1 - 7.7e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ38367.1 - 9.1e-21 74.6 3.3 1.1e-20 74.3 3.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EEQ38367.1 - 3e-07 30.6 0.2 7.1e-07 29.4 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EEQ38367.1 - 0.0015 19.0 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A YscO-like PF16789.5 EEQ38367.1 - 0.0048 16.9 0.6 0.0058 16.7 0.6 1.2 1 0 0 1 1 1 1 YscO-like protein DUF3391 PF11871.8 EEQ38367.1 - 0.14 12.7 1.5 0.22 12.1 1.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) DUF4811 PF16069.5 EEQ38367.1 - 0.35 10.7 5.4 0.28 11.0 4.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4811) PGAP1 PF07819.13 EEQ38368.1 - 2e-92 309.1 0.0 3.4e-92 308.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EEQ38368.1 - 0.027 15.1 0.0 0.055 14.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ38368.1 - 0.034 13.4 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ38368.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3294 PF07957.11 EEQ38369.1 - 3.3e-60 203.5 2.8 3.6e-60 203.3 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Cyclophil_like2 PF18050.1 EEQ38369.1 - 0.1 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Cyclophilin-like family DUF16 PF01519.16 EEQ38369.1 - 0.86 10.1 7.1 0.5 10.9 5.0 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 BRE1 PF08647.11 EEQ38369.1 - 1.4 9.0 6.6 2.2 8.4 0.8 2.6 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase DUF680 PF05079.12 EEQ38371.1 - 3.5 8.4 7.1 14 6.4 1.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF680) Ribosomal_L29e PF01779.17 EEQ38372.1 - 2.9e-20 72.3 14.4 3.8e-20 71.9 14.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family PH_BEACH PF14844.6 EEQ38372.1 - 0.084 13.0 0.9 0.1 12.7 0.9 1.1 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH Ribosomal_L7Ae PF01248.26 EEQ38373.1 - 3.3e-23 81.2 0.4 5.6e-23 80.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FliC_SP PF12613.8 EEQ38373.1 - 0.031 14.8 0.5 0.066 13.7 0.5 1.5 1 0 0 1 1 1 0 Flagellin structural protein PQ-loop PF04193.14 EEQ38374.1 - 4.9e-29 99.9 0.8 1.6e-18 66.2 0.1 3.4 4 0 0 4 4 4 2 PQ loop repeat Comm PF15957.5 EEQ38374.1 - 0.15 12.4 0.5 0.48 10.8 0.1 2.1 1 1 1 2 2 2 0 Commissureless Zn_clus PF00172.18 EEQ38375.1 - 0.00012 22.2 14.5 0.00023 21.2 14.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EEQ38375.1 - 0.0053 15.8 1.9 0.039 13.0 1.8 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4200 PF13863.6 EEQ38376.1 - 0.072 13.5 1.1 0.072 13.5 1.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) EF-hand_14 PF17959.1 EEQ38376.1 - 0.096 13.0 4.3 0.55 10.6 1.1 3.2 2 2 0 2 2 2 0 EF-hand domain ADIP PF11559.8 EEQ38376.1 - 0.16 12.0 17.3 0.25 11.4 5.6 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding FPP PF05911.11 EEQ38376.1 - 0.42 8.7 17.4 0.14 10.3 10.3 2.1 1 1 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF2570 PF10828.8 EEQ38376.1 - 0.64 9.9 12.5 4.3 7.2 0.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) FlaC_arch PF05377.11 EEQ38376.1 - 0.99 9.8 16.2 2.3 8.7 1.6 4.1 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) TolA_bind_tri PF16331.5 EEQ38376.1 - 1 9.5 13.7 0.21 11.7 2.6 3.5 2 1 1 3 3 3 0 TolA binding protein trimerisation PI3K_P85_iSH2 PF16454.5 EEQ38376.1 - 2 8.0 15.0 0.19 11.3 7.6 2.5 2 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain IL34 PF15036.6 EEQ38376.1 - 2.1 8.4 6.8 6.2 6.9 0.1 2.4 1 1 1 2 2 2 0 Interleukin 34 BORCS7 PF16088.5 EEQ38376.1 - 2.8 8.2 7.1 20 5.5 3.5 3.1 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 CREPT PF16566.5 EEQ38376.1 - 3 8.0 15.8 0.19 11.9 3.7 3.0 2 1 0 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour DUF641 PF04859.12 EEQ38376.1 - 3.3 8.1 13.7 0.62 10.4 2.1 2.6 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DUF3847 PF12958.7 EEQ38376.1 - 9.5 6.4 10.8 0.85 9.8 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3847) Mto2_bdg PF12808.7 EEQ38376.1 - 9.8 6.6 9.6 2.4 8.5 0.4 3.3 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region zf-Tim10_DDP PF02953.15 EEQ38377.1 - 7.3e-20 70.4 5.8 1.1e-19 69.9 5.8 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tti2 PF10521.9 EEQ38378.1 - 9.5e-59 199.2 0.2 1.2e-58 198.9 0.2 1.1 1 0 0 1 1 1 1 Tti2 family Uricase PF01014.18 EEQ38378.1 - 0.088 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Uricase Indigoidine_A PF04227.12 EEQ38379.1 - 2.2e-122 408.0 0.0 2.6e-122 407.8 0.0 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein AbfB PF05270.13 EEQ38379.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain PfkB PF00294.24 EEQ38380.1 - 0.00015 21.2 0.0 0.031 13.6 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Cep57_CLD_2 PF14197.6 EEQ38380.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Chalcone_2 PF16035.5 EEQ38381.1 - 4.9e-49 166.9 0.1 6.1e-49 166.6 0.1 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EEQ38381.1 - 1.8e-05 24.9 0.3 0.065 13.3 0.1 2.2 1 1 1 2 2 2 2 Chalcone isomerase-like Chalcone PF02431.15 EEQ38381.1 - 0.018 14.5 0.3 0.03 13.7 0.0 1.5 2 0 0 2 2 2 0 Chalcone-flavanone isomerase NTP_transferase PF00483.23 EEQ38383.1 - 7.6e-52 176.4 0.0 1.2e-51 175.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EEQ38383.1 - 1.3e-10 40.6 5.8 2.1e-08 33.6 0.2 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EEQ38383.1 - 1.6e-10 41.6 0.0 2.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EEQ38383.1 - 0.00089 19.0 3.8 0.65 9.8 0.2 3.4 5 0 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase IspD PF01128.19 EEQ38383.1 - 0.0038 17.0 0.0 0.015 15.1 0.0 2.0 3 0 0 3 3 3 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 EEQ38383.1 - 0.057 11.6 0.2 0.18 9.9 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 EEQ38383.1 - 0.057 13.3 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase MFS_1 PF07690.16 EEQ38384.1 - 5.6e-16 58.4 22.2 1.2e-15 57.3 22.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily FBPase PF00316.20 EEQ38385.1 - 2.5e-80 268.4 0.4 3.2e-80 268.1 0.4 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EEQ38385.1 - 0.0051 16.4 0.0 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 Inositol monophosphatase family NdhM PF10664.9 EEQ38385.1 - 0.028 14.7 0.0 0.06 13.6 0.0 1.6 1 0 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M TraF PF13728.6 EEQ38386.1 - 0.018 14.8 0.5 0.024 14.5 0.5 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DUF2868 PF11067.8 EEQ38386.1 - 0.12 11.9 0.2 0.12 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) SecY PF00344.20 EEQ38387.1 - 1.5e-66 224.7 11.9 1.9e-66 224.4 11.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EEQ38387.1 - 1.6e-16 59.8 0.1 4.8e-16 58.3 0.1 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p QCR10 PF09796.9 EEQ38387.1 - 0.15 12.1 3.2 2.2 8.4 0.1 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AAA PF00004.29 EEQ38388.1 - 2.4e-37 128.3 0.0 4.7e-37 127.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ38388.1 - 5.7e-07 29.2 0.0 1.5e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EEQ38388.1 - 7.8e-07 29.0 0.4 2.6e-05 24.1 0.0 3.2 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EEQ38388.1 - 1.7e-05 24.6 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ38388.1 - 2.3e-05 24.7 0.2 0.0059 16.9 0.1 2.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EEQ38388.1 - 0.0004 19.7 0.0 0.00073 18.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EEQ38388.1 - 0.00046 20.6 0.1 0.0067 16.8 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EEQ38388.1 - 0.0011 19.0 0.0 0.0045 17.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EEQ38388.1 - 0.0016 18.8 0.2 0.69 10.3 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 EEQ38388.1 - 0.0048 16.3 0.1 0.0095 15.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EEQ38388.1 - 0.0053 16.9 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EEQ38388.1 - 0.0065 16.5 0.0 0.023 14.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EEQ38388.1 - 0.0082 15.9 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EEQ38388.1 - 0.0098 16.1 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EEQ38388.1 - 0.017 14.5 0.0 3.6 7.0 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein DUF815 PF05673.13 EEQ38388.1 - 0.031 13.4 0.0 0.066 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EEQ38388.1 - 0.048 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ38388.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EEQ38388.1 - 0.073 13.6 0.0 0.3 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ38388.1 - 0.085 12.8 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 1 0 NACHT domain AAA_24 PF13479.6 EEQ38388.1 - 0.096 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EEQ38388.1 - 0.12 11.7 0.1 2.5 7.4 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 EEQ38388.1 - 0.13 11.7 0.0 0.43 10.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 EEQ38388.1 - 0.14 11.9 0.0 0.5 10.0 0.0 1.9 1 1 1 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 EEQ38388.1 - 0.15 12.5 1.4 2.6 8.6 0.0 2.9 3 0 0 3 3 3 0 ABC transporter Apq12 PF12716.7 EEQ38389.1 - 4.6e-09 36.1 9.1 1.1e-08 34.9 9.1 1.6 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis AA_permease_C PF13906.6 EEQ38389.1 - 0.0033 17.4 0.4 0.0033 17.4 0.4 2.2 2 0 0 2 2 2 1 C-terminus of AA_permease DUF3867 PF12983.7 EEQ38389.1 - 0.07 13.2 0.4 0.11 12.5 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3867) TMEM247 PF15444.6 EEQ38389.1 - 2.1 8.4 5.2 3.6 7.6 5.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 247 MFS_1 PF07690.16 EEQ38390.1 - 4.9e-39 134.2 38.3 1.7e-38 132.5 38.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ38390.1 - 2.4e-17 62.6 23.7 3.9e-17 61.9 23.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EEQ38390.1 - 6.2e-11 41.5 29.2 1.2e-06 27.3 1.1 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 EEQ38390.1 - 4.3e-09 35.8 10.1 4.3e-09 35.8 10.1 3.9 3 1 0 3 3 3 1 Sugar (and other) transporter DUF2207 PF09972.9 EEQ38390.1 - 7.2 5.2 9.6 0.22 10.2 1.6 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DnaJ-X PF14308.6 EEQ38391.1 - 9.8e-54 182.0 7.7 9.8e-54 182.0 7.7 2.0 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EEQ38391.1 - 1.5e-24 85.9 0.1 5.4e-24 84.1 0.1 2.0 1 0 0 1 1 1 1 DnaJ domain DUF4671 PF15710.5 EEQ38391.1 - 0.00014 20.9 0.9 0.0002 20.4 0.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4671) Nop53 PF07767.11 EEQ38391.1 - 0.00098 18.6 6.2 0.00098 18.6 6.2 1.6 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) T3SS_needle_F PF09392.10 EEQ38391.1 - 0.0086 16.3 2.0 6 7.2 0.0 3.7 3 1 1 4 4 4 2 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF OmdA PF13376.6 EEQ38391.1 - 2.2 8.4 9.6 0.14 12.2 1.1 3.1 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Use1 PF09753.9 EEQ38391.1 - 2.4 7.8 15.5 1.3 8.6 13.2 1.7 1 1 1 2 2 2 0 Membrane fusion protein Use1 Complex1_LYR PF05347.15 EEQ38392.1 - 3.2e-17 62.3 0.9 3.9e-17 62.0 0.9 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ38392.1 - 1.2e-07 32.3 1.2 1.4e-07 32.2 1.2 1.0 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EEQ38392.1 - 0.023 15.3 0.0 0.026 15.1 0.0 1.1 1 0 0 1 1 1 0 Complex1_LYR-like FMO-like PF00743.19 EEQ38393.1 - 2.8e-06 26.1 0.0 3.3e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EEQ38393.1 - 0.00011 22.3 0.0 0.00016 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EEQ38393.1 - 0.00012 22.1 0.0 0.00015 21.8 0.0 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 EEQ38393.1 - 0.0064 16.1 0.3 0.0089 15.6 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EEQ38393.1 - 0.083 12.0 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pho86 PF11124.8 EEQ38394.1 - 2.6e-93 312.7 4.1 2.9e-93 312.5 4.1 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Peptidase_M64 PF09471.10 EEQ38394.1 - 0.016 14.7 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 IgA Peptidase M64 DUF1282 PF06930.12 EEQ38394.1 - 0.063 13.0 0.2 0.12 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Lectin_leg-like PF03388.13 EEQ38395.1 - 2.4e-55 187.4 0.0 3.1e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 EEQ38395.1 - 4.3e-09 36.7 0.1 6.2e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 EEQ38395.1 - 0.00029 20.5 0.0 0.0026 17.3 0.0 2.0 1 1 0 1 1 1 1 Legume lectin domain InaF-motif PF15018.6 EEQ38395.1 - 0.036 13.9 2.3 0.086 12.7 2.3 1.6 1 0 0 1 1 1 0 TRP-interacting helix FeoB_associated PF12669.7 EEQ38395.1 - 6.2 7.3 8.0 1.7 9.1 3.0 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Mannitol_dh_C PF08125.13 EEQ38396.1 - 0.023 14.2 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Mannitol dehydrogenase C-terminal domain TAFII28 PF04719.14 EEQ38396.1 - 0.065 13.3 0.1 0.097 12.8 0.1 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region IU_nuc_hydro PF01156.19 EEQ38397.1 - 2.2e-78 263.9 0.0 2.6e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Herpes_U34 PF04541.13 EEQ38397.1 - 0.14 11.4 0.2 5.5 6.2 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus virion protein U34 Abhydro_lipase PF04083.16 EEQ38398.1 - 1.9e-17 62.6 0.0 3.9e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EEQ38398.1 - 0.00011 21.9 0.1 0.00024 20.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold MFS_1_like PF12832.7 EEQ38398.1 - 0.0061 15.5 0.0 0.0076 15.1 0.0 1.2 1 0 0 1 1 1 1 MFS_1 like family Chlorophyllase2 PF12740.7 EEQ38398.1 - 0.012 14.5 0.0 0.027 13.4 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme LCAT PF02450.15 EEQ38398.1 - 0.036 13.3 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UPF0565 PF10561.9 EEQ38398.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Abhydrolase_6 PF12697.7 EEQ38398.1 - 0.15 12.6 0.0 0.27 11.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DAO PF01266.24 EEQ38399.1 - 2.2e-23 83.4 0.0 2.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Peripla_BP_4 PF13407.6 EEQ38399.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein domain Mito_carr PF00153.27 EEQ38400.1 - 1.1e-61 204.7 3.9 3.4e-22 78.2 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ38400.1 - 0.0021 17.3 1.5 0.33 10.1 0.6 2.9 1 1 1 2 2 2 2 Gammaproteobacterial serine protease 2-Hacid_dh_C PF02826.19 EEQ38401.1 - 1.8e-54 183.8 0.0 2.6e-54 183.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ38401.1 - 1.9e-11 43.8 0.0 3.6e-11 42.9 0.0 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEQ38401.1 - 8e-06 26.1 0.0 1.9e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EEQ38401.1 - 5.1e-05 22.9 0.0 9.7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EEQ38401.1 - 0.00079 20.0 0.0 0.0019 18.7 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent CNP1 PF08750.11 EEQ38401.1 - 0.09 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 CNP1-like family XdhC_C PF13478.6 EEQ38401.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Shikimate_DH PF01488.20 EEQ38401.1 - 0.11 12.5 0.0 0.42 10.7 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2863 PF11062.8 EEQ38401.1 - 0.12 10.8 0.0 0.18 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2863) Peptidase_M28 PF04389.17 EEQ38402.1 - 7.2e-40 136.8 0.1 1e-39 136.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EEQ38402.1 - 4e-13 49.2 0.3 1.8e-12 47.1 0.2 2.1 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EEQ38402.1 - 0.00011 21.9 0.0 0.00031 20.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EEQ38402.1 - 0.057 12.4 0.0 0.15 11.0 0.0 1.5 1 1 0 2 2 2 0 M42 glutamyl aminopeptidase DnaJ PF00226.31 EEQ38403.1 - 1.3e-20 73.3 5.5 4.7e-20 71.5 5.5 2.1 1 0 0 1 1 1 1 DnaJ domain DUF4578 PF15147.6 EEQ38403.1 - 7.7 7.4 13.3 22 6.0 13.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4578) AAA PF00004.29 EEQ38404.1 - 7.9e-43 146.1 0.0 1.4e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ38404.1 - 7.1e-14 51.3 0.1 1.5e-13 50.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EEQ38404.1 - 2.3e-07 30.9 0.0 7e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ38404.1 - 1.1e-06 28.8 0.0 2.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EEQ38404.1 - 7.5e-06 26.4 0.1 0.00026 21.4 0.0 2.9 3 1 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 EEQ38404.1 - 1.3e-05 25.5 0.5 0.0063 16.8 0.5 2.4 1 1 0 1 1 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 EEQ38404.1 - 0.00016 21.6 0.1 0.00049 20.0 0.1 1.9 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 EEQ38404.1 - 0.00038 20.2 0.0 0.00073 19.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEQ38404.1 - 0.00075 19.7 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ38404.1 - 0.0036 17.9 0.2 0.031 14.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EEQ38404.1 - 0.0046 16.7 0.0 0.0099 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EEQ38404.1 - 0.0077 16.1 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EEQ38404.1 - 0.0082 15.4 0.0 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EEQ38404.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EEQ38404.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ38404.1 - 0.023 14.7 0.0 0.044 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EEQ38404.1 - 0.025 14.1 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ38404.1 - 0.028 14.5 0.0 0.056 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4763 PF15960.5 EEQ38404.1 - 0.028 13.7 3.1 0.049 12.9 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) RNA_helicase PF00910.22 EEQ38404.1 - 0.032 14.6 0.0 0.062 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATG16 PF08614.11 EEQ38404.1 - 0.034 14.4 2.9 0.061 13.6 2.9 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) PhoH PF02562.16 EEQ38404.1 - 0.035 13.5 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF724 PF05266.14 EEQ38404.1 - 0.038 13.8 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) AAA_24 PF13479.6 EEQ38404.1 - 0.038 13.7 0.0 0.099 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEQ38404.1 - 0.044 13.6 0.3 0.75 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEQ38404.1 - 0.046 13.2 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Tropomyosin PF00261.20 EEQ38404.1 - 0.053 12.9 1.6 0.15 11.4 0.5 2.0 2 0 0 2 2 2 0 Tropomyosin TMF_TATA_bd PF12325.8 EEQ38404.1 - 0.053 13.7 0.6 0.17 12.1 0.6 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EEQ38404.1 - 0.08 12.7 2.1 0.18 11.6 2.1 1.6 1 0 0 1 1 1 0 Septum formation initiator APG6_N PF17675.1 EEQ38404.1 - 0.082 13.4 0.6 0.16 12.5 0.6 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region ATPase PF06745.13 EEQ38404.1 - 0.082 12.2 0.4 0.16 11.3 0.0 1.7 2 0 0 2 2 1 0 KaiC NACHT PF05729.12 EEQ38404.1 - 0.087 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 EEQ38404.1 - 0.1 12.3 0.0 0.55 9.9 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.6 EEQ38404.1 - 0.11 13.0 0.0 0.39 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain eIF_4G1 PF12152.8 EEQ38405.1 - 9e-22 77.0 0.7 9e-22 77.0 0.7 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.19 EEQ38405.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 MIF4G domain MIF4G PF02854.19 EEQ38406.1 - 3.2e-18 66.1 0.6 4.3e-18 65.7 0.6 1.2 1 0 0 1 1 1 1 MIF4G domain PI_PP_C PF18365.1 EEQ38406.1 - 0.013 15.5 0.3 0.031 14.3 0.1 1.8 2 1 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain AAA PF00004.29 EEQ38407.1 - 3.7e-17 63.0 0.1 1.5e-16 61.0 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ38407.1 - 1.8e-13 50.5 0.0 7.2e-13 48.6 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEQ38407.1 - 1.4e-06 28.3 0.0 5.2e-06 26.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EEQ38407.1 - 2.7e-06 27.5 0.0 7.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ38407.1 - 4.7e-06 27.1 0.7 0.0041 17.5 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_assoc_2 PF16193.5 EEQ38407.1 - 1.1e-05 25.6 0.0 0.00023 21.5 0.0 2.6 2 0 0 2 2 2 1 AAA C-terminal domain AAA_33 PF13671.6 EEQ38407.1 - 2.5e-05 24.5 0.0 0.00062 19.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ38407.1 - 2.6e-05 24.5 0.1 0.0025 18.1 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ38407.1 - 3.1e-05 24.5 0.0 0.0011 19.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EEQ38407.1 - 0.00037 20.2 0.0 0.044 13.5 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.14 EEQ38407.1 - 0.00056 20.1 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EEQ38407.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EEQ38407.1 - 0.0024 17.7 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EEQ38407.1 - 0.0029 18.0 0.0 0.017 15.5 0.0 2.3 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 EEQ38407.1 - 0.003 17.0 0.1 0.032 13.6 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EEQ38407.1 - 0.0085 16.4 0.0 0.041 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EEQ38407.1 - 0.017 14.7 0.2 0.077 12.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EEQ38407.1 - 0.021 14.6 0.0 0.045 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EEQ38407.1 - 0.028 14.8 0.8 8 6.8 0.3 2.5 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.6 EEQ38407.1 - 0.035 14.5 0.0 0.13 12.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ38407.1 - 0.045 13.7 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EEQ38407.1 - 0.054 14.0 0.1 0.46 11.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EEQ38407.1 - 0.076 12.9 0.2 0.59 10.0 0.0 2.3 3 0 0 3 3 2 0 RsgA GTPase NTPase_1 PF03266.15 EEQ38407.1 - 0.082 12.8 0.1 0.47 10.4 0.0 2.3 3 0 0 3 3 3 0 NTPase AAA_7 PF12775.7 EEQ38407.1 - 0.11 12.0 0.0 0.36 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EEQ38407.1 - 0.14 11.8 0.1 2 8.1 0.1 2.8 3 1 0 3 3 3 0 AAA domain ResIII PF04851.15 EEQ38407.1 - 0.25 11.3 1.6 2.8 7.9 0.1 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit LIM_bind PF01803.16 EEQ38408.1 - 4.3e-44 150.9 1.2 4.3e-44 150.9 1.2 4.7 2 2 1 3 3 3 1 LIM-domain binding protein EPL1 PF10513.9 EEQ38408.1 - 0.58 10.5 19.2 0.1 13.0 13.2 2.3 2 0 0 2 2 2 0 Enhancer of polycomb-like CDC45 PF02724.14 EEQ38408.1 - 3.6 5.8 8.7 4.7 5.4 8.7 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM76 PF16046.5 EEQ38408.1 - 8.8 5.6 16.6 18 4.6 16.6 1.4 1 0 0 1 1 1 0 FAM76 protein PAPA-1 PF04795.12 EEQ38409.1 - 2.5e-18 66.7 6.1 2.5e-18 66.7 6.1 3.1 1 1 1 2 2 2 1 PAPA-1-like conserved region Wx5_PLAF3D7 PF09688.10 EEQ38409.1 - 5 7.1 12.6 0.26 11.3 4.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (Wx5_PLAF3D7) Neugrin PF06413.11 EEQ38411.1 - 1.4e-07 31.8 3.9 1.4e-07 31.8 3.9 2.0 2 1 0 2 2 2 1 Neugrin HTH_32 PF13565.6 EEQ38411.1 - 0.021 15.4 4.2 0.024 15.2 0.7 2.2 2 0 0 2 2 2 0 Homeodomain-like domain DUF1187 PF06688.11 EEQ38411.1 - 1.8 8.9 5.6 3.2 8.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1187) VID27_N PF17748.1 EEQ38412.1 - 1.6e-48 164.8 1.1 1.6e-48 164.8 1.1 2.4 2 1 0 2 2 2 1 VID27 N-terminal region Prothymosin PF03247.14 EEQ38412.1 - 7.5 7.1 30.3 0.44 11.0 22.4 2.3 2 0 0 2 2 2 0 Prothymosin/parathymosin family RGS PF00615.19 EEQ38414.1 - 4.7e-06 26.9 0.2 1.2e-05 25.6 0.2 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 EEQ38414.1 - 0.075 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain bZIP_2 PF07716.15 EEQ38415.1 - 6.7e-10 38.9 7.5 2.4e-09 37.1 7.5 2.0 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EEQ38415.1 - 0.06 13.5 9.4 0.2 11.8 9.4 1.9 1 1 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.18 EEQ38415.1 - 0.082 13.2 2.0 0.25 11.7 2.0 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family AbiEi_3_N PF17194.4 EEQ38415.1 - 0.1 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain CPSase_L_D2 PF02786.17 EEQ38416.1 - 6.3e-81 270.9 0.2 1.1e-80 270.1 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EEQ38416.1 - 1.3e-66 224.1 0.0 2.3e-66 223.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EEQ38416.1 - 1.2e-39 135.2 0.0 2.6e-39 134.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EEQ38416.1 - 5.9e-31 106.8 0.0 1.7e-30 105.3 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EEQ38416.1 - 1.5e-24 87.0 0.0 2.9e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EEQ38416.1 - 1.3e-16 60.2 9.5 2.1e-16 59.5 4.7 3.1 3 0 0 3 3 3 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EEQ38416.1 - 1.2e-07 31.5 1.9 0.0047 16.7 0.2 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EEQ38416.1 - 2.8e-06 27.0 0.0 6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EEQ38416.1 - 1.1e-05 25.0 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EEQ38416.1 - 5.2e-05 23.3 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EEQ38416.1 - 0.01 16.5 0.5 9.9 6.9 0.1 3.0 2 0 0 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 EEQ38416.1 - 0.02 14.8 1.0 0.12 12.3 0.4 2.5 2 0 0 2 2 2 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 EEQ38416.1 - 0.029 13.6 0.3 0.77 8.9 0.1 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion RnfC_N PF13375.6 EEQ38416.1 - 0.041 13.8 0.2 0.26 11.2 0.4 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain RimK PF08443.11 EEQ38416.1 - 0.041 13.5 0.0 0.39 10.3 0.0 2.2 1 1 0 1 1 1 0 RimK-like ATP-grasp domain NQRA PF05896.11 EEQ38416.1 - 0.044 13.2 0.4 0.082 12.3 0.4 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATPgrasp_ST PF14397.6 EEQ38416.1 - 0.088 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp PYNP_C PF07831.13 EEQ38416.1 - 1.4 8.7 3.4 3 7.6 0.1 2.8 2 1 1 3 3 3 0 Pyrimidine nucleoside phosphorylase C-terminal domain DASH_Duo1 PF08651.10 EEQ38417.1 - 4.2e-21 74.5 5.4 4.2e-21 74.5 5.4 2.1 2 0 0 2 2 2 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 EEQ38417.1 - 0.00011 22.5 2.9 0.00011 22.5 2.9 2.0 1 1 1 2 2 2 1 DASH complex subunit Dad2 bZIP_1 PF00170.21 EEQ38417.1 - 0.0025 17.9 13.3 0.028 14.5 5.9 2.4 2 0 0 2 2 2 2 bZIP transcription factor APG6_N PF17675.1 EEQ38417.1 - 0.0038 17.8 17.9 0.01 16.4 17.9 1.6 1 1 0 1 1 1 1 Apg6 coiled-coil region DUF484 PF04340.12 EEQ38417.1 - 0.0054 16.5 6.8 0.02 14.6 6.8 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF484 M PF02370.16 EEQ38417.1 - 0.014 15.8 17.8 0.018 15.5 7.8 3.7 2 1 1 3 3 3 0 M protein repeat Wtap PF17098.5 EEQ38417.1 - 0.016 15.1 7.9 0.02 14.8 7.9 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family WAPL PF07814.13 EEQ38417.1 - 0.017 14.0 5.6 0.021 13.6 5.6 1.1 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin bZIP_2 PF07716.15 EEQ38417.1 - 0.058 13.5 8.5 0.058 13.5 8.5 2.7 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 EEQ38417.1 - 0.21 12.1 15.3 0.73 10.3 0.3 2.4 2 0 0 2 2 2 0 Cell division protein ZapB DivIC PF04977.15 EEQ38417.1 - 0.22 11.3 12.7 0.13 12.0 5.3 2.5 2 1 0 2 2 2 0 Septum formation initiator Cortex-I_coil PF09304.10 EEQ38417.1 - 0.51 10.6 10.5 0.86 9.8 0.9 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil NPV_P10 PF05531.12 EEQ38417.1 - 0.71 10.4 7.2 0.66 10.5 0.8 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.18 EEQ38417.1 - 1.1 10.1 10.6 0.3 11.8 2.7 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Prefoldin PF02996.17 EEQ38417.1 - 1.3 9.0 13.4 4.6 7.2 4.9 2.2 2 0 0 2 2 2 0 Prefoldin subunit KLRAQ PF10205.9 EEQ38417.1 - 2.6 8.4 13.4 2.9 8.2 7.3 2.2 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein DUF4404 PF14357.6 EEQ38417.1 - 3.3 8.4 12.5 0.37 11.5 2.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Nsp1_C PF05064.13 EEQ38417.1 - 4 7.3 15.7 8.6 6.2 1.4 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4446 PF14584.6 EEQ38417.1 - 4.8 7.2 7.8 10 6.1 0.6 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF4407 PF14362.6 EEQ38417.1 - 7.1 5.9 11.3 9.8 5.4 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med31 PF05669.12 EEQ38418.1 - 2.9e-38 129.8 5.0 3.5e-38 129.5 5.0 1.1 1 0 0 1 1 1 1 SOH1 Scs3p PF10261.9 EEQ38419.1 - 1.1e-70 237.9 12.4 2.6e-70 236.7 12.4 1.5 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 EEQ38419.1 - 3.5 7.4 12.7 0.028 14.2 2.3 2.4 2 1 0 2 2 2 0 PAP2 superfamily He_PIG PF05345.12 EEQ38420.1 - 1.4e-11 44.4 17.1 3.2e-06 27.2 1.9 4.7 5 0 0 5 5 5 3 Putative Ig domain SKG6 PF08693.10 EEQ38420.1 - 2.4e-05 23.7 0.3 6.1e-05 22.4 0.3 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MLANA PF14991.6 EEQ38420.1 - 3.5e-05 24.1 0.0 9.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Protein melan-A Mid2 PF04478.12 EEQ38420.1 - 5.4e-05 23.1 0.1 0.00018 21.4 0.1 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4448 PF14610.6 EEQ38420.1 - 7.6e-05 22.6 0.0 0.00019 21.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EEQ38420.1 - 0.00022 21.2 0.9 0.00046 20.1 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family Orf78 PF06024.12 EEQ38420.1 - 0.041 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 Orf78 (ac78) Shisa PF13908.6 EEQ38420.1 - 0.045 14.0 0.9 0.14 12.4 0.9 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Sarcoglycan_2 PF05510.13 EEQ38420.1 - 0.082 11.7 0.1 0.24 10.2 0.0 1.8 1 1 0 1 1 1 0 Sarcoglycan alpha/epsilon DAG1 PF05454.11 EEQ38420.1 - 0.17 11.2 0.0 0.37 10.1 0.0 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) 4HBT PF03061.22 EEQ38421.1 - 0.00054 20.3 0.2 1.8 9.0 0.0 3.0 2 1 0 2 2 2 2 Thioesterase superfamily Transket_pyr PF02779.24 EEQ38422.1 - 1.9e-44 151.4 0.0 2.7e-44 151.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EEQ38422.1 - 7.8e-39 132.4 0.1 1.9e-38 131.1 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Acatn PF13000.7 EEQ38423.1 - 8.4e-194 645.1 18.2 2e-130 435.9 8.2 2.7 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 PQ-loop PF04193.14 EEQ38424.1 - 1.3e-32 111.3 15.3 5.2e-16 58.2 5.3 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 EEQ38424.1 - 0.073 13.1 0.5 0.073 13.1 0.5 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Metallophos PF00149.28 EEQ38425.1 - 1.1e-31 111.0 0.5 1.6e-31 110.4 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Aminotran_3 PF00202.21 EEQ38426.1 - 5.1e-117 391.0 0.1 6.7e-117 390.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Cation_efflux PF01545.21 EEQ38427.1 - 6.5e-07 29.3 3.0 1.2e-06 28.4 3.0 1.5 1 1 0 1 1 1 1 Cation efflux family DUF2457 PF10446.9 EEQ38427.1 - 6.9 5.7 11.0 12 5.0 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CITED PF04487.12 EEQ38428.1 - 0.066 13.3 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 CITED Gal4_dimer PF03902.13 EEQ38428.1 - 0.28 11.4 1.4 0.74 10.0 0.2 2.4 2 0 0 2 2 2 0 Gal4-like dimerisation domain SH3_1 PF00018.28 EEQ38429.1 - 3.1e-05 23.5 0.1 4.1e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 SH3 domain Myosin_head PF00063.21 EEQ38431.1 - 4.6e-228 758.8 7.1 5.5e-228 758.6 7.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EEQ38431.1 - 2.8e-39 134.7 0.0 5.3e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Hpr_kinase_C PF07475.12 EEQ38431.1 - 0.00028 20.5 0.3 0.87 9.1 0.0 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain RsgA_GTPase PF03193.16 EEQ38431.1 - 0.01 15.8 0.4 0.027 14.4 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EEQ38431.1 - 0.036 14.5 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EEQ38431.1 - 0.044 14.0 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain IQ PF00612.27 EEQ38431.1 - 0.08 12.8 9.4 0.28 11.1 3.5 2.6 1 1 1 2 2 2 0 IQ calmodulin-binding motif NACHT PF05729.12 EEQ38431.1 - 0.087 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EEQ38431.1 - 0.13 12.7 0.0 0.5 10.8 0.0 2.1 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.32 EEQ38432.1 - 2.3e-55 183.3 40.8 3.3e-10 40.4 0.1 9.2 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38432.1 - 1.2e-15 57.5 5.8 0.00018 21.7 0.1 5.8 3 3 4 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EEQ38432.1 - 1.6e-10 41.3 0.0 3.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 EEQ38432.1 - 2.7e-07 30.7 0.2 0.028 14.3 0.0 3.7 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EEQ38432.1 - 0.00023 20.0 11.4 1.6 7.3 0.5 5.3 3 3 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ38432.1 - 0.00026 20.1 0.1 0.44 9.4 0.0 4.0 4 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EEQ38432.1 - 0.00094 18.0 2.8 0.016 13.9 1.2 2.5 2 1 0 2 2 2 1 Nup133 N terminal like Frtz PF11768.8 EEQ38432.1 - 0.0038 15.6 0.0 0.62 8.3 0.0 2.3 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EEQ38432.1 - 0.046 13.1 0.0 1.3 8.3 0.0 3.0 4 0 0 4 4 4 0 WD40-like domain FAD_binding_9 PF08021.11 EEQ38432.1 - 0.11 12.7 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Med7 PF05983.11 EEQ38433.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 MED7 protein MFAP1 PF06991.11 EEQ38434.1 - 0.018 14.9 0.7 0.022 14.6 0.7 1.4 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Pkinase PF00069.25 EEQ38436.1 - 1.2e-70 237.9 0.0 1.9e-70 237.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38436.1 - 2e-39 135.4 0.0 4.2e-39 134.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ38436.1 - 9.7e-07 28.4 0.0 4.3e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EEQ38436.1 - 4.5e-05 23.5 0.5 0.0027 17.7 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EEQ38436.1 - 0.0019 17.3 0.1 0.0036 16.4 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EEQ38436.1 - 0.008 15.0 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EEQ38436.1 - 0.03 13.9 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EEQ38436.1 - 0.032 13.6 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPT PF13446.6 EEQ38436.1 - 0.062 13.2 0.1 6.6 6.7 0.1 2.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein Img2 PF05046.14 EEQ38437.1 - 2e-18 66.4 1.0 2.5e-18 66.1 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) zf-C2H2 PF00096.26 EEQ38438.1 - 1.6e-13 50.2 50.7 0.00012 22.3 0.8 8.9 8 0 0 8 8 8 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ38438.1 - 7.9e-12 45.0 46.3 6e-08 32.8 0.2 7.3 7 0 0 7 7 7 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ38438.1 - 1.3e-06 28.7 53.8 0.11 13.4 0.8 9.6 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EEQ38438.1 - 0.0001 21.9 18.3 0.00034 20.3 1.8 5.0 4 0 0 4 4 4 2 zinc-finger C2H2-type FOXP-CC PF16159.5 EEQ38438.1 - 0.0013 19.4 0.6 0.0013 19.4 0.6 7.7 7 2 2 9 9 9 3 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EEQ38438.1 - 0.019 15.0 0.4 0.019 15.0 0.4 6.1 6 1 1 7 7 7 0 C2H2-type zinc finger zf-met PF12874.7 EEQ38438.1 - 0.094 13.1 22.7 1 9.8 0.4 6.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEQ38438.1 - 2.1 8.8 0.0 2.1 8.8 0.0 6.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding PAT1 PF09770.9 EEQ38439.1 - 1.6e-107 360.9 56.3 6.4e-55 186.9 0.3 3.3 1 1 2 3 3 3 3 Topoisomerase II-associated protein PAT1 Ubiquitin_3 PF14836.6 EEQ38439.1 - 0.046 13.7 0.0 0.36 10.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain G6B PF15096.6 EEQ38439.1 - 0.31 10.8 1.1 0.68 9.7 1.1 1.5 1 0 0 1 1 1 0 G6B family Chorismate_bind PF00425.18 EEQ38440.1 - 3.4e-70 236.6 0.0 5.2e-70 235.9 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EEQ38440.1 - 5.4e-29 101.3 0.0 9.1e-29 100.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EEQ38440.1 - 3.3e-13 50.0 0.1 8.5e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EEQ38440.1 - 0.0034 17.2 0.0 0.085 12.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase C26 Uso1_p115_head PF04869.14 EEQ38441.1 - 3.6e-27 95.3 0.1 2.3e-26 92.7 0.1 2.6 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region DUF4407 PF14362.6 EEQ38441.1 - 0.0017 17.8 8.7 0.0017 17.8 8.7 9.6 3 2 6 9 9 9 2 Domain of unknown function (DUF4407) ATG16 PF08614.11 EEQ38441.1 - 0.0022 18.3 20.2 0.0022 18.3 20.2 13.8 1 1 12 14 14 14 4 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 EEQ38441.1 - 0.0026 17.9 21.4 0.0026 17.9 21.4 13.9 2 2 10 13 13 13 3 Uncharacterised protein family (UPF0242) N-terminus Rad52_Rad22 PF04098.15 EEQ38442.1 - 8.5e-32 110.2 0.4 1.1e-31 109.8 0.4 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein IKI3 PF04762.12 EEQ38443.1 - 0 1072.3 1.2 0 1071.3 1.5 1.3 2 0 0 2 2 2 1 IKI3 family ANAPC3 PF12895.7 EEQ38443.1 - 0.3 11.3 4.5 0.44 10.8 1.5 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EEQ38443.1 - 0.78 9.8 4.0 2.3 8.3 0.8 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat U-box PF04564.15 EEQ38444.1 - 5.1e-19 68.2 0.1 8.7e-19 67.5 0.1 1.4 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EEQ38444.1 - 0.003 17.6 0.0 0.0052 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein V_ATPase_I PF01496.19 EEQ38445.1 - 7.5e-260 864.3 0.0 9.3e-260 864.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.8 EEQ38445.1 - 0.023 14.9 1.3 3.5 7.9 0.2 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Sec34 PF04136.15 EEQ38445.1 - 0.69 9.8 4.5 0.34 10.8 0.3 2.5 3 0 0 3 3 3 0 Sec34-like family NPV_P10 PF05531.12 EEQ38445.1 - 6 7.4 6.9 42 4.7 0.7 3.3 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RIX1 PF08167.12 EEQ38446.1 - 2.2e-45 154.7 2.2 2.6e-45 154.5 0.9 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF3453 PF11935.8 EEQ38446.1 - 0.011 15.3 0.2 0.22 11.1 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3453) RRN3 PF05327.11 EEQ38447.1 - 1.2e-151 506.0 7.2 1.7e-151 505.6 7.2 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF1539 PF07560.11 EEQ38447.1 - 0.0027 17.8 0.4 0.022 14.9 0.3 2.6 2 1 0 2 2 2 1 Domain of Unknown Function (DUF1539) CHASE6_C PF17150.4 EEQ38447.1 - 0.12 13.0 0.0 1.7 9.3 0.0 2.7 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain JAB PF01398.21 EEQ38448.1 - 8.3e-06 25.8 0.0 1.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GATA PF00320.27 EEQ38449.1 - 3.1e-13 49.1 8.4 5.9e-13 48.2 8.4 1.5 1 0 0 1 1 1 1 GATA zinc finger STE PF02200.16 EEQ38450.1 - 1.1e-58 196.4 0.5 1.9e-58 195.6 0.5 1.5 1 0 0 1 1 1 1 STE like transcription factor CLASP_N PF12348.8 EEQ38451.1 - 8.1e-85 284.0 4.4 1.7e-75 253.5 0.3 3.7 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.6 EEQ38451.1 - 0.00093 19.6 0.7 0.96 10.0 0.0 4.2 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 EEQ38451.1 - 0.0033 17.5 0.0 3.3 8.2 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EEQ38451.1 - 0.024 15.0 0.1 8.3 6.9 0.0 3.6 3 0 0 3 3 3 0 HEAT repeats Condensin2nSMC PF12422.8 EEQ38451.1 - 0.033 14.4 2.1 3.9 7.6 0.0 3.7 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit AbiJ_NTD5 PF18865.1 EEQ38451.1 - 0.042 13.7 0.1 0.58 10.0 0.1 2.9 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 NB-ARC PF00931.22 EEQ38451.1 - 0.15 11.2 2.9 3.4 6.8 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain Peptidase_C13 PF01650.18 EEQ38452.1 - 2.1e-44 152.0 0.2 2.3e-44 151.8 0.2 1.0 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C80 PF11713.8 EEQ38452.1 - 0.089 13.0 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Peptidase C80 family Helicase_C PF00271.31 EEQ38453.1 - 1.2e-15 57.8 0.1 4.3e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ38453.1 - 9.5e-10 38.7 0.0 2.2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ38453.1 - 0.00098 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EEQ38453.1 - 0.0021 17.3 0.0 0.0044 16.3 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_2 PF13307.6 EEQ38453.1 - 0.014 15.6 0.3 2.7 8.1 0.0 2.6 3 0 0 3 3 3 0 Helicase C-terminal domain Pol_alpha_B_N PF08418.10 EEQ38454.1 - 5.4e-41 141.2 5.5 1.2e-40 140.0 5.5 1.6 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EEQ38454.1 - 3.4e-37 127.8 0.1 5.1e-37 127.3 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B La PF05383.17 EEQ38455.1 - 5.7e-22 77.5 0.3 1.8e-21 75.9 0.1 2.0 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 EEQ38455.1 - 0.015 15.1 0.6 0.36 10.7 0.6 2.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ala_racemase_N PF01168.20 EEQ38456.1 - 1.1e-24 87.3 0.0 1.3e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Leptin PF02024.15 EEQ38456.1 - 0.0075 16.1 0.3 0.27 11.0 0.1 2.3 1 1 1 2 2 2 1 Leptin ArlS_N PF18719.1 EEQ38458.1 - 0.46 10.7 6.3 0.29 11.4 3.8 1.9 1 1 1 2 2 2 0 ArlS sensor domain PAP1 PF08601.10 EEQ38458.1 - 4.4 6.9 21.7 5.6 6.6 21.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Anoctamin PF04547.12 EEQ38459.1 - 1.6e-27 96.5 0.1 1.9e-27 96.3 0.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoctamin PF04547.12 EEQ38460.1 - 9.7e-11 41.1 3.3 1.2e-10 40.8 3.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel FUSC_2 PF13515.6 EEQ38460.1 - 0.017 15.3 0.2 0.027 14.6 0.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein-like SH3_1 PF00018.28 EEQ38461.1 - 8e-12 44.6 2.8 9.1e-11 41.2 0.1 2.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEQ38461.1 - 5.3e-10 39.0 0.1 1.3e-09 37.8 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ38461.1 - 3e-08 33.2 0.0 5.7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain WD40 PF00400.32 EEQ38462.1 - 9.6e-17 61.1 2.6 0.0001 23.0 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38462.1 - 4.5e-11 42.9 0.0 0.0066 16.7 0.0 4.9 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EEQ38462.1 - 0.023 13.3 0.0 2.1 6.8 0.0 2.6 2 1 1 3 3 3 0 Cytochrome D1 heme domain Nup160 PF11715.8 EEQ38462.1 - 0.12 10.9 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CAP PF00188.26 EEQ38464.1 - 2.4e-19 70.4 7.3 2.4e-19 70.4 7.3 2.1 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Adaptin_N PF01602.20 EEQ38465.1 - 9.7e-79 265.3 4.9 6.3e-67 226.3 0.3 2.1 2 0 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EEQ38465.1 - 6.1e-06 26.4 0.4 0.00089 19.3 0.1 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Alpha_adaptin_C PF02296.16 EEQ38465.1 - 0.00047 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_2 PF13646.6 EEQ38465.1 - 0.0034 17.7 0.4 0.95 9.9 0.1 2.8 2 0 0 2 2 2 2 HEAT repeats Arm PF00514.23 EEQ38465.1 - 0.021 14.9 0.2 4.3 7.5 0.1 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Mt_ATP-synt_D PF05873.12 EEQ38466.1 - 9.5e-18 64.5 2.8 1.3e-17 64.1 2.8 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) RelB PF04221.12 EEQ38466.1 - 0.016 15.2 0.5 0.3 11.1 0.0 2.8 3 1 0 3 3 3 0 RelB antitoxin Dor1 PF04124.12 EEQ38466.1 - 0.017 13.8 1.1 0.021 13.5 1.1 1.2 1 0 0 1 1 1 0 Dor1-like family Syntaxin PF00804.25 EEQ38466.1 - 0.058 13.1 4.4 1 9.0 0.3 2.9 2 1 1 3 3 3 0 Syntaxin Vps51 PF08700.11 EEQ38466.1 - 0.067 13.3 4.6 2.4 8.3 0.2 2.4 1 1 1 2 2 2 0 Vps51/Vps67 MbeB_N PF04837.12 EEQ38466.1 - 0.087 13.1 1.2 0.087 13.1 1.2 2.6 2 0 0 2 2 2 0 MbeB-like, N-term conserved region T2SSM_b PF10741.9 EEQ38466.1 - 0.11 12.3 0.1 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b F-box_4 PF15966.5 EEQ38467.1 - 8.2e-05 22.5 0.1 0.00037 20.3 0.1 2.1 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 EEQ38467.1 - 0.00012 21.9 0.8 0.00028 20.7 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEQ38467.1 - 0.072 13.0 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 F-box domain COX7a PF02238.15 EEQ38468.1 - 3.9e-24 84.8 0.3 4.3e-24 84.7 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII zf-C3HC4 PF00097.25 EEQ38469.1 - 1.8e-08 34.1 8.3 1.8e-08 34.1 8.3 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ38469.1 - 2.9e-08 33.5 5.4 2.9e-08 33.5 5.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ38469.1 - 3.2e-08 33.3 8.4 3.2e-08 33.3 8.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ38469.1 - 4.5e-08 33.3 9.0 4.5e-08 33.3 9.0 2.2 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EEQ38469.1 - 8.5e-08 32.1 6.5 2.4e-07 30.6 6.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EEQ38469.1 - 1.3e-07 31.3 7.0 1.3e-07 31.3 7.0 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ38469.1 - 4.7e-07 29.7 8.2 4.7e-07 29.7 8.2 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EEQ38469.1 - 8.5e-06 25.8 11.0 8.5e-06 25.8 11.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EEQ38469.1 - 3.2e-05 24.1 6.4 3.2e-05 24.1 6.4 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EEQ38469.1 - 0.00058 20.0 4.8 0.00058 20.0 4.8 1.8 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EEQ38469.1 - 0.001 18.9 3.4 0.001 18.9 3.4 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein HUN PF08729.10 EEQ38469.1 - 0.0015 18.5 1.8 0.0015 18.5 1.8 2.5 2 0 0 2 2 1 1 HPC2 and ubinuclein domain zf-ANAPC11 PF12861.7 EEQ38469.1 - 0.036 14.1 1.9 0.036 14.1 1.9 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3716 PF12511.8 EEQ38469.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) zf-RING_11 PF17123.5 EEQ38469.1 - 2.2 8.1 6.6 6.9 6.5 6.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger zinc_ribbon_5 PF13719.6 EEQ38469.1 - 4.5 7.1 5.3 34 4.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_4 PF14570.6 EEQ38469.1 - 5.7 6.8 13.8 0.11 12.3 5.9 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ran_BP1 PF00638.18 EEQ38470.1 - 2e-28 99.1 0.3 1.1e-27 96.7 0.0 2.1 2 0 0 2 2 2 1 RanBP1 domain MMPL PF03176.15 EEQ38470.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 MMPL family Methyltransf_31 PF13847.6 EEQ38471.1 - 1.8e-29 102.5 0.0 2.5e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ38471.1 - 1.4e-07 32.1 0.0 2.4e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ38471.1 - 1.1e-06 29.2 0.0 2.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EEQ38471.1 - 6.7e-05 22.9 0.0 9e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ38471.1 - 0.00024 21.7 0.0 0.0004 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ38471.1 - 0.00051 19.9 0.0 0.0008 19.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Vps51 PF08700.11 EEQ38472.1 - 3.9e-09 36.5 1.0 8.7e-09 35.4 0.5 1.8 1 1 0 1 1 1 1 Vps51/Vps67 E2F_CC-MB PF16421.5 EEQ38472.1 - 0.057 13.8 3.7 0.13 12.6 1.4 2.5 2 1 1 3 3 3 0 E2F transcription factor CC-MB domain Pannexin_like PF12534.8 EEQ38472.1 - 0.71 8.9 3.3 0.94 8.5 3.3 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 FAM76 PF16046.5 EEQ38472.1 - 0.86 8.9 5.2 1.1 8.6 5.2 1.1 1 0 0 1 1 1 0 FAM76 protein CAF1C_H4-bd PF12265.8 EEQ38473.1 - 3.8e-18 65.5 0.0 9.7e-18 64.2 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EEQ38473.1 - 1.9e-10 41.1 15.9 0.0023 18.7 0.6 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38473.1 - 1.7e-08 34.7 0.2 0.069 13.5 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ38473.1 - 5e-07 29.8 0.0 0.016 15.1 0.0 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Palm_thioest PF02089.15 EEQ38475.1 - 3.8e-72 243.0 0.0 4.5e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EEQ38475.1 - 0.00085 18.9 0.2 0.002 17.7 0.2 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Caudal_act PF04731.12 EEQ38475.1 - 0.15 12.4 0.1 0.25 11.7 0.1 1.3 1 0 0 1 1 1 0 Caudal like protein activation region Abhydrolase_2 PF02230.16 EEQ38475.1 - 0.16 11.8 0.9 2.9 7.6 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Ribosomal_L1 PF00687.21 EEQ38476.1 - 1.5e-36 126.1 1.7 1.8e-36 125.8 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family AA_permease_2 PF13520.6 EEQ38477.1 - 5.8e-47 160.5 52.6 8.2e-47 160.0 52.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ38477.1 - 5.1e-32 111.1 49.9 6.8e-32 110.7 49.9 1.0 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.18 EEQ38477.1 - 1.8 7.2 37.7 1.6e+02 0.8 30.1 3.3 1 1 1 2 2 2 0 Transmembrane amino acid transporter protein Tim17 PF02466.19 EEQ38478.1 - 4.7e-31 107.4 8.3 6.1e-31 107.1 8.3 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3180 PF11377.8 EEQ38478.1 - 2.7 8.2 6.7 8.5 6.5 0.4 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3180) Pkinase PF00069.25 EEQ38479.1 - 4.9e-51 173.6 0.0 1.7e-50 171.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38479.1 - 4.5e-21 75.3 0.0 8.3e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ38479.1 - 1.4e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ38479.1 - 0.01 15.4 0.3 0.019 14.6 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EEQ38479.1 - 0.039 13.3 0.1 0.081 12.3 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EEQ38479.1 - 0.069 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EEQ38479.1 - 0.084 12.2 0.1 1.6 8.0 0.0 2.2 1 1 1 2 2 2 0 Kinase-like RNA_pol_Rpb4 PF03874.16 EEQ38480.1 - 4.5e-32 111.0 6.4 7.5e-32 110.2 6.4 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb4 GCV_T PF01571.21 EEQ38480.1 - 0.027 13.8 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Aminomethyltransferase folate-binding domain GTP_EFTU PF00009.27 EEQ38481.1 - 1.4e-36 125.8 0.0 2.8e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EEQ38481.1 - 6.5e-19 67.9 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EEQ38481.1 - 8.2e-18 64.2 0.0 8.8e-17 60.9 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ38481.1 - 3.1e-10 40.3 0.5 6e-10 39.4 0.5 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFTUD2 PF16004.5 EEQ38481.1 - 1.2e-08 35.6 13.3 9.7e-07 29.4 13.3 2.4 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus MMR_HSR1 PF01926.23 EEQ38481.1 - 0.00089 19.3 0.0 0.0024 17.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.6 EEQ38481.1 - 0.015 15.4 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 Elongation Factor G, domain II TniB PF05621.11 EEQ38481.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein DUF2420 PF10336.9 EEQ38482.1 - 5.9e-28 97.0 0.2 5.9e-28 97.0 0.2 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2420) SWIRM PF04433.17 EEQ38483.1 - 2.1e-30 104.9 2.3 1.9e-29 101.8 0.1 2.6 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EEQ38483.1 - 5.5e-21 74.3 4.5 5.5e-21 74.3 4.5 2.0 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EEQ38483.1 - 4e-09 36.5 0.0 8.5e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ38483.1 - 4.8e-07 29.9 0.1 1.7e-06 28.2 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L27A PF00828.19 EEQ38483.1 - 0.14 12.8 1.4 27 5.4 0.0 3.1 3 0 0 3 3 3 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Ribosomal_L22 PF00237.19 EEQ38484.1 - 7.2e-39 132.2 0.6 1e-38 131.7 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e polyprenyl_synt PF00348.17 EEQ38485.1 - 3.9e-96 321.0 0.2 4.9e-96 320.7 0.2 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 EEQ38485.1 - 0.023 14.1 0.1 0.069 12.5 0.0 1.9 3 0 0 3 3 3 0 Terpene synthase family, metal binding domain Ebp2 PF05890.12 EEQ38486.1 - 8.5e-86 287.8 24.5 8.5e-86 287.8 24.5 2.4 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Glyco_transf_15 PF01793.16 EEQ38487.1 - 3.4e-111 371.6 12.0 4.3e-111 371.3 12.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Complex1_51K PF01512.17 EEQ38488.1 - 1.5e-45 154.8 0.0 3.1e-45 153.7 0.0 1.5 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EEQ38488.1 - 1.5e-29 101.9 0.1 3.4e-29 100.8 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EEQ38488.1 - 3.7e-06 26.7 0.0 9.4e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 SLBB domain MIOX PF05153.15 EEQ38490.1 - 3.6e-120 400.2 6.4 4.6e-120 399.8 6.4 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EEQ38490.1 - 0.15 12.3 2.1 0.6 10.3 0.0 2.8 2 1 1 3 3 3 0 HD domain TFIIA PF03153.13 EEQ38491.1 - 0.12 12.4 31.6 0.22 11.5 31.6 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_1 PF01148.20 EEQ38492.1 - 2.9e-79 266.6 16.4 3.8e-79 266.2 16.4 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Cir_N PF10197.9 EEQ38493.1 - 8.9e-14 51.4 9.1 8.9e-14 51.4 9.1 2.1 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 EEQ38493.1 - 2.6e-10 41.1 0.6 2.6e-10 41.1 0.6 3.4 2 1 1 3 3 3 1 Pre-mRNA splicing factor PRMT5 PF05185.16 EEQ38494.1 - 3.9e-40 137.5 0.0 6.3e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EEQ38494.1 - 4.3e-20 72.3 0.3 7.3e-20 71.6 0.3 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 EEQ38494.1 - 4e-07 30.6 0.0 8.5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ38494.1 - 0.00066 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EEQ38494.1 - 0.0024 17.0 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.17 EEQ38494.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase tRNA-synt_1f PF01921.18 EEQ38494.1 - 0.23 10.3 0.4 2.3 7.1 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) CKS PF01111.19 EEQ38495.1 - 9e-33 112.4 0.2 1.6e-32 111.6 0.1 1.4 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit PI3_PI4_kinase PF00454.27 EEQ38496.1 - 4.9e-52 177.2 0.5 1.9e-51 175.3 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 EEQ38496.1 - 5.8e-22 77.5 1.5 5.8e-22 77.5 1.5 3.5 4 0 0 4 4 4 1 UME (NUC010) domain FAT PF02259.23 EEQ38496.1 - 4.3e-18 65.7 0.7 4.3e-18 65.7 0.7 2.6 2 1 0 2 2 2 1 FAT domain FATC PF02260.20 EEQ38496.1 - 1.6e-13 50.2 0.0 4.5e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 FATC domain DUF5439 PF17507.2 EEQ38496.1 - 0.19 11.9 1.6 0.44 10.8 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5439) PH_11 PF15413.6 EEQ38497.1 - 1.7e-32 112.0 0.1 6.5e-32 110.1 0.1 2.1 1 0 0 1 1 1 1 Pleckstrin homology domain MMM1 PF10296.9 EEQ38497.1 - 1.6e-06 27.4 4.4 4.8e-05 22.6 0.0 3.6 3 1 1 4 4 4 2 Maintenance of mitochondrial morphology protein 1 Per1 PF04080.13 EEQ38499.1 - 4.8e-88 295.2 8.0 5.9e-88 294.9 8.0 1.1 1 0 0 1 1 1 1 Per1-like family Ceramidase PF05875.12 EEQ38499.1 - 0.046 13.1 10.2 2.5 7.5 0.3 3.2 2 1 0 3 3 3 0 Ceramidase DUF4585 PF15232.6 EEQ38500.1 - 0.093 12.8 0.1 0.4 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4585) DUF4834 PF16118.5 EEQ38500.1 - 0.41 11.6 2.5 3.4 8.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) SIR2 PF02146.17 EEQ38502.1 - 1.2e-38 132.8 0.0 8.1e-38 130.1 0.0 1.9 1 1 0 1 1 1 1 Sir2 family YdjO PF14169.6 EEQ38502.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Cold-inducible protein YdjO Bromodomain PF00439.25 EEQ38503.1 - 1e-32 112.0 1.7 4.2e-17 62.0 0.7 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EEQ38503.1 - 1.5e-14 53.9 0.0 3.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 BAH domain Glyco_hydro_17 PF00332.18 EEQ38504.1 - 2.2e-07 30.8 0.8 2.1e-06 27.6 0.1 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 DUF4127 PF13552.6 EEQ38504.1 - 0.074 11.6 0.1 3.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4127) Ribosomal_S5 PF00333.20 EEQ38504.1 - 0.17 11.9 1.4 0.37 10.8 0.4 2.0 3 0 0 3 3 3 0 Ribosomal protein S5, N-terminal domain V-SNARE_C PF12352.8 EEQ38505.1 - 3.3e-11 43.3 1.6 3.3e-11 43.3 1.6 1.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EEQ38505.1 - 1.9e-06 27.7 1.3 5.5e-06 26.2 0.0 2.2 2 1 0 2 2 2 1 Sec20 TnsD PF15978.5 EEQ38505.1 - 0.038 13.0 0.9 0.13 11.2 0.4 1.8 2 0 0 2 2 2 0 Tn7-like transposition protein D Sigma70_r4 PF04545.16 EEQ38505.1 - 0.038 13.5 0.7 0.13 11.8 0.7 2.0 1 1 0 1 1 1 0 Sigma-70, region 4 TPR_MLP1_2 PF07926.12 EEQ38505.1 - 0.83 9.7 8.0 9.9 6.2 7.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1640 PF07798.11 EEQ38506.1 - 4e-56 189.8 9.7 4.5e-56 189.6 9.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF2267 PF10025.9 EEQ38506.1 - 0.019 15.2 0.2 0.071 13.4 0.0 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2267) XhlA PF10779.9 EEQ38506.1 - 0.041 14.1 7.4 0.15 12.2 0.1 2.7 2 1 0 2 2 2 0 Haemolysin XhlA WXG100 PF06013.12 EEQ38506.1 - 0.066 13.5 2.0 0.95 9.7 0.3 2.6 2 1 0 2 2 2 0 Proteins of 100 residues with WXG FlaC_arch PF05377.11 EEQ38506.1 - 0.094 13.1 4.6 2.4 8.6 0.5 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Lectin_N PF03954.14 EEQ38506.1 - 0.12 12.1 5.9 0.067 12.9 3.3 1.9 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Uds1 PF15456.6 EEQ38506.1 - 0.2 11.8 7.7 0.046 13.9 3.7 1.8 2 0 0 2 2 2 0 Up-regulated During Septation GBP_C PF02841.14 EEQ38506.1 - 0.23 10.8 13.3 0.16 11.4 11.8 1.5 1 1 1 2 2 2 0 Guanylate-binding protein, C-terminal domain SlyX PF04102.12 EEQ38506.1 - 0.24 12.0 6.1 27 5.5 0.2 3.4 2 1 1 3 3 3 0 SlyX DUF5082 PF16888.5 EEQ38506.1 - 0.44 10.8 11.0 1.6 9.0 11.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 EEQ38506.1 - 0.65 9.3 8.6 0.52 9.6 3.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) UPF0449 PF15136.6 EEQ38506.1 - 0.99 9.9 5.9 0.74 10.3 2.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF2203 PF09969.9 EEQ38506.1 - 3.1 8.5 8.9 12 6.7 2.7 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1451 PF07295.11 EEQ38506.1 - 3.7 7.6 7.9 33 4.5 4.2 2.7 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF1690 PF07956.11 EEQ38506.1 - 6.4 7.2 12.6 1.8 8.9 7.5 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) RCC1 PF00415.18 EEQ38507.1 - 7e-18 65.0 0.2 0.00039 21.0 0.0 6.0 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEQ38507.1 - 6e-15 54.6 4.8 0.00014 21.5 0.4 4.6 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DsbC_N PF10411.9 EEQ38507.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.9 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus PMM PF03332.13 EEQ38508.1 - 6.6e-113 375.9 0.5 7.4e-113 375.7 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EEQ38508.1 - 5.9e-07 29.5 0.0 8.6e-06 25.7 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EEQ38508.1 - 0.00073 19.1 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Ribosomal_L16 PF00252.18 EEQ38509.1 - 4.6e-41 139.9 0.1 5.9e-41 139.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C2H2_jaz PF12171.8 EEQ38510.1 - 4.1e-09 36.5 2.3 4.1e-09 36.5 2.3 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Sec8_exocyst PF04048.14 EEQ38510.1 - 0.059 13.3 0.3 0.11 12.4 0.1 1.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain zf-C2H2_2 PF12756.7 EEQ38510.1 - 0.06 13.7 0.4 0.11 12.9 0.2 1.5 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EEQ38510.1 - 0.068 14.0 0.1 0.15 12.9 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ38510.1 - 0.17 12.4 0.3 0.31 11.6 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ38510.1 - 0.42 11.1 1.9 5 7.7 0.3 2.4 2 0 0 2 2 2 0 Zinc-finger double domain OTU PF02338.19 EEQ38511.1 - 4.4e-05 24.0 0.0 7.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EEQ38511.1 - 0.0084 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain AATF-Che1 PF13339.6 EEQ38512.1 - 4.5e-08 33.9 0.0 4.5e-08 33.9 0.0 3.1 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor DUF2457 PF10446.9 EEQ38512.1 - 0.022 13.9 24.5 0.026 13.7 24.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Aldedh PF00171.22 EEQ38512.1 - 0.052 12.1 0.1 0.065 11.7 0.1 1.1 1 0 0 1 1 1 0 Aldehyde dehydrogenase family TFIIF_alpha PF05793.12 EEQ38512.1 - 0.28 9.7 30.4 0.31 9.6 30.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.15 EEQ38512.1 - 0.94 8.2 19.2 1.1 7.9 19.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 EEQ38512.1 - 1.8 8.3 20.6 2.7 7.7 20.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop14 PF04147.12 EEQ38512.1 - 2.6 6.2 33.2 3.5 5.7 33.2 1.2 1 0 0 1 1 1 0 Nop14-like family Plasmodium_Vir PF05795.11 EEQ38512.1 - 3.9 6.8 13.6 5.4 6.3 13.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Hid1 PF12722.7 EEQ38512.1 - 5.1 5.1 17.3 5.6 5.0 17.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SURF2 PF05477.11 EEQ38512.1 - 6.8 6.3 24.8 10 5.7 24.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Ribosomal_S13 PF00416.22 EEQ38513.1 - 2.4e-20 73.2 1.2 3.3e-18 66.3 1.2 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EEQ38513.1 - 0.0015 17.4 0.0 0.0016 17.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Imm39 PF15568.6 EEQ38513.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 39 DNA_pol_lambd_f PF10391.9 EEQ38513.1 - 0.13 12.1 0.1 0.47 10.3 0.1 1.9 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda EOS1 PF12326.8 EEQ38514.1 - 5.8e-46 156.6 16.1 9e-36 123.4 10.6 2.6 2 1 1 3 3 3 2 N-glycosylation protein Rod_cone_degen PF15201.6 EEQ38514.1 - 0.037 14.1 1.1 0.079 13.1 1.1 1.5 1 0 0 1 1 1 0 Progressive rod-cone degeneration Tropomyosin_1 PF12718.7 EEQ38515.1 - 1.5e-41 141.9 30.6 1.9e-41 141.5 30.6 1.1 1 0 0 1 1 1 1 Tropomyosin like KELK PF15796.5 EEQ38515.1 - 5.9e-05 23.4 26.5 0.00038 20.8 4.5 3.0 1 1 2 3 3 3 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase Tropomyosin PF00261.20 EEQ38515.1 - 5.9e-05 22.5 27.7 0.00012 21.6 27.7 1.5 1 1 0 1 1 1 1 Tropomyosin Myosin_tail_1 PF01576.19 EEQ38515.1 - 0.0001 20.3 23.8 0.00013 19.9 23.8 1.2 1 0 0 1 1 1 1 Myosin tail GAS PF13851.6 EEQ38515.1 - 0.00012 21.5 27.5 0.00022 20.6 19.6 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 EEQ38515.1 - 0.00044 20.3 29.7 0.00047 20.2 9.7 2.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 EEQ38515.1 - 0.0011 19.2 26.3 0.0015 18.8 26.3 1.1 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 KLRAQ PF10205.9 EEQ38515.1 - 0.0034 17.6 18.4 0.11 12.7 11.3 2.1 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Filament PF00038.21 EEQ38515.1 - 0.0044 16.7 23.3 0.022 14.3 23.3 1.8 1 1 0 1 1 1 1 Intermediate filament protein bZIP_1 PF00170.21 EEQ38515.1 - 0.0054 16.8 24.1 0.017 15.2 2.1 3.6 1 1 1 2 2 2 1 bZIP transcription factor TelA PF05816.11 EEQ38515.1 - 0.0069 15.5 9.3 0.0069 15.5 9.3 1.9 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) DUF724 PF05266.14 EEQ38515.1 - 0.0086 15.9 23.2 0.1 12.4 23.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF724) FliD_C PF07195.12 EEQ38515.1 - 0.0099 15.3 15.1 0.087 12.2 1.1 2.5 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Rho_Binding PF08912.11 EEQ38515.1 - 0.01 16.6 3.6 0.01 16.6 3.6 3.1 1 1 2 3 3 3 0 Rho Binding NPV_P10 PF05531.12 EEQ38515.1 - 0.012 16.0 10.3 0.21 12.0 0.5 2.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EEQ38515.1 - 0.013 15.5 14.6 0.041 13.9 6.3 2.1 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.11 EEQ38515.1 - 0.013 14.4 26.7 0.018 13.9 26.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 EEQ38515.1 - 0.019 14.8 4.9 0.019 14.8 4.9 3.6 1 1 2 3 3 2 0 Septum formation initiator DUF3287 PF11690.8 EEQ38515.1 - 0.021 14.6 4.5 0.073 12.8 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Sec20 PF03908.13 EEQ38515.1 - 0.023 14.6 4.3 0.023 14.6 4.3 2.3 1 1 1 2 2 2 0 Sec20 LPP PF04728.13 EEQ38515.1 - 0.023 15.1 10.1 0.058 13.8 0.8 3.2 2 1 1 3 3 2 0 Lipoprotein leucine-zipper TPR_MLP1_2 PF07926.12 EEQ38515.1 - 0.025 14.6 30.4 1.1 9.3 30.3 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein EzrA PF06160.12 EEQ38515.1 - 0.031 12.4 25.9 0.037 12.2 25.9 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA bZIP_2 PF07716.15 EEQ38515.1 - 0.033 14.3 1.7 0.033 14.3 1.7 4.0 2 1 1 4 4 4 0 Basic region leucine zipper HAP1_N PF04849.13 EEQ38515.1 - 0.036 13.3 23.6 0.054 12.7 23.6 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region DUF4200 PF13863.6 EEQ38515.1 - 0.037 14.4 29.0 0.067 13.6 20.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) HMMR_N PF15905.5 EEQ38515.1 - 0.037 13.5 29.1 0.045 13.2 29.1 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Rootletin PF15035.6 EEQ38515.1 - 0.037 14.1 23.4 0.31 11.0 6.5 2.2 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF812 PF05667.11 EEQ38515.1 - 0.038 12.9 25.6 0.049 12.5 25.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ADIP PF11559.8 EEQ38515.1 - 0.038 14.1 23.9 0.52 10.4 3.0 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DHR10 PF18595.1 EEQ38515.1 - 0.04 14.0 28.6 0.11 12.6 13.6 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain Snapin_Pallidin PF14712.6 EEQ38515.1 - 0.041 14.3 18.1 0.35 11.3 4.9 2.2 1 1 1 2 2 2 0 Snapin/Pallidin ATG16 PF08614.11 EEQ38515.1 - 0.057 13.6 26.5 0.11 12.7 18.5 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 EEQ38515.1 - 0.058 10.9 22.8 0.17 9.4 22.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Uso1_p115_C PF04871.13 EEQ38515.1 - 0.066 13.6 29.8 0.073 13.4 20.8 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2959 PF11172.8 EEQ38515.1 - 0.069 13.3 13.7 0.32 11.1 7.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) IFT57 PF10498.9 EEQ38515.1 - 0.091 11.7 20.5 0.17 10.9 2.7 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Prefoldin_2 PF01920.20 EEQ38515.1 - 0.094 12.7 28.4 17 5.4 28.2 2.8 1 1 0 1 1 1 0 Prefoldin subunit DUF4795 PF16043.5 EEQ38515.1 - 0.1 12.2 20.9 0.13 11.9 20.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) IZUMO PF15005.6 EEQ38515.1 - 0.11 13.0 9.3 0.14 12.7 9.3 1.2 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated KASH_CCD PF14662.6 EEQ38515.1 - 0.12 12.2 25.3 0.52 10.1 25.2 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Ax_dynein_light PF10211.9 EEQ38515.1 - 0.13 12.2 27.8 0.47 10.4 6.2 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain ZapB PF06005.12 EEQ38515.1 - 0.14 12.7 31.7 2.9 8.4 6.0 3.2 2 1 0 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 EEQ38515.1 - 0.16 12.5 33.7 1.2 9.7 33.2 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region THOC7 PF05615.13 EEQ38515.1 - 0.17 12.2 24.2 2 8.7 12.9 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 ABC_tran_CTD PF16326.5 EEQ38515.1 - 0.18 12.1 28.4 1.1 9.6 10.8 2.6 1 1 1 2 2 2 0 ABC transporter C-terminal domain ERM PF00769.19 EEQ38515.1 - 0.18 11.6 28.9 0.95 9.2 28.9 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Spc24 PF08286.11 EEQ38515.1 - 0.19 12.0 25.4 0.31 11.3 4.6 3.0 1 1 1 2 2 1 0 Spc24 subunit of Ndc80 HAUS-augmin3 PF14932.6 EEQ38515.1 - 0.25 10.9 24.6 0.32 10.5 24.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 PI3K_P85_iSH2 PF16454.5 EEQ38515.1 - 0.26 10.9 23.2 0.63 9.6 0.6 2.7 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain GrpE PF01025.19 EEQ38515.1 - 0.27 10.9 27.6 0.079 12.6 5.4 2.7 1 1 1 2 2 2 0 GrpE Fez1 PF06818.15 EEQ38515.1 - 0.27 11.6 22.6 0.6 10.5 18.3 2.0 1 1 1 2 2 2 0 Fez1 Prefoldin PF02996.17 EEQ38515.1 - 0.29 11.1 24.8 0.46 10.4 2.8 3.0 2 1 1 3 3 3 0 Prefoldin subunit CLZ PF16526.5 EEQ38515.1 - 0.31 11.4 20.2 0.17 12.3 3.4 2.4 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels WXG100 PF06013.12 EEQ38515.1 - 0.32 11.2 10.5 6.6 7.1 0.5 3.3 2 2 0 2 2 2 0 Proteins of 100 residues with WXG DUF4472 PF14739.6 EEQ38515.1 - 0.33 11.7 23.6 0.47 11.2 3.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) ZYG-11_interact PF05884.12 EEQ38515.1 - 0.37 10.2 4.3 0.44 9.9 4.3 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 DUF5082 PF16888.5 EEQ38515.1 - 0.41 10.9 19.1 1.4 9.2 2.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Lectin_N PF03954.14 EEQ38515.1 - 0.41 10.4 13.8 0.76 9.5 1.7 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF4201 PF13870.6 EEQ38515.1 - 0.41 10.3 24.2 1.7 8.3 21.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Fzo_mitofusin PF04799.13 EEQ38515.1 - 0.42 10.2 14.8 0.77 9.3 5.1 2.3 1 1 1 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 EEQ38515.1 - 0.43 10.6 14.0 0.82 9.7 6.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EEQ38515.1 - 0.44 10.9 22.2 12 6.3 12.1 3.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynamitin PF04912.14 EEQ38515.1 - 0.46 9.8 23.3 1.1 8.6 23.3 1.6 1 1 0 1 1 1 0 Dynamitin FlaC_arch PF05377.11 EEQ38515.1 - 0.48 10.8 21.3 0.72 10.3 0.4 4.0 1 1 3 4 4 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 EEQ38515.1 - 0.55 10.3 34.2 4.8 7.3 13.6 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding T2SSM PF04612.12 EEQ38515.1 - 0.6 10.2 7.8 0.69 10.0 2.8 2.2 1 1 0 2 2 2 0 Type II secretion system (T2SS), protein M Uds1 PF15456.6 EEQ38515.1 - 0.62 10.2 21.0 0.59 10.3 17.9 1.9 1 1 1 2 2 2 0 Up-regulated During Septation Mago_nashi PF02792.14 EEQ38515.1 - 0.63 10.2 7.1 0.28 11.3 5.2 1.4 1 1 1 2 2 1 0 Mago nashi protein HalX PF08663.10 EEQ38515.1 - 0.63 10.4 22.5 0.37 11.1 9.0 3.5 1 1 2 3 3 3 0 HalX domain Herpes_UL6 PF01763.16 EEQ38515.1 - 0.75 8.2 14.4 3 6.3 14.1 1.9 1 1 0 1 1 1 0 Herpesvirus UL6 like Nup54 PF13874.6 EEQ38515.1 - 0.82 9.8 14.5 1.3 9.2 14.5 1.3 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4407 PF14362.6 EEQ38515.1 - 0.86 8.9 16.1 1.3 8.3 16.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BRE1 PF08647.11 EEQ38515.1 - 0.92 9.6 27.8 0.09 12.9 12.2 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase Occludin_ELL PF07303.13 EEQ38515.1 - 1 10.1 16.7 12 6.7 5.1 2.2 1 1 1 2 2 2 0 Occludin homology domain DUF2203 PF09969.9 EEQ38515.1 - 1.1 10.0 17.0 0.97 10.2 6.3 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Sec2p PF06428.11 EEQ38515.1 - 1.1 9.2 25.1 5.1 7.1 1.8 2.4 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p Sec34 PF04136.15 EEQ38515.1 - 1.2 9.1 17.0 0.24 11.3 8.2 2.0 1 1 1 2 2 2 0 Sec34-like family Alanine_zipper PF11839.8 EEQ38515.1 - 1.2 9.6 7.7 14 6.1 1.2 3.1 1 1 2 3 3 3 0 Alanine-zipper, major outer membrane lipoprotein DUF4890 PF16231.5 EEQ38515.1 - 1.2 9.6 15.2 0.87 10.1 12.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4890) DMPK_coil PF08826.10 EEQ38515.1 - 1.3 9.2 23.5 1.2 9.3 2.3 3.3 1 1 1 3 3 3 0 DMPK coiled coil domain like HrpB7 PF09486.10 EEQ38515.1 - 1.3 9.4 14.5 28 5.1 0.7 2.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DUF4559 PF15112.6 EEQ38515.1 - 1.3 8.6 15.3 1.5 8.4 15.3 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) SOGA PF11365.8 EEQ38515.1 - 1.3 10.2 18.8 0.73 11.0 15.2 2.1 1 1 1 2 2 1 0 Protein SOGA HOOK PF05622.12 EEQ38515.1 - 1.5 6.9 25.9 1.8 6.6 25.9 1.1 1 0 0 1 1 1 0 HOOK protein RPW8 PF05659.11 EEQ38515.1 - 1.5 8.5 11.5 0.73 9.5 8.4 1.8 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fib_alpha PF08702.10 EEQ38515.1 - 1.5 9.0 16.3 2.3 8.4 14.1 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3552 PF12072.8 EEQ38515.1 - 1.6 8.1 27.6 1.5 8.2 16.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) BST2 PF16716.5 EEQ38515.1 - 1.6 9.4 23.5 0.31 11.7 12.1 2.1 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 TMPIT PF07851.13 EEQ38515.1 - 1.6 7.9 18.4 2.5 7.2 17.1 1.7 1 1 0 1 1 1 0 TMPIT-like protein DUF745 PF05335.13 EEQ38515.1 - 1.8 8.3 16.1 3.7 7.2 8.4 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF745) SlyX PF04102.12 EEQ38515.1 - 1.9 9.1 14.5 1e+04 -2.8 14.5 3.2 1 1 0 1 1 0 0 SlyX HemX PF04375.14 EEQ38515.1 - 2 7.6 20.5 2.1 7.6 12.4 2.0 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase HetR_C PF18460.1 EEQ38515.1 - 2.2 8.3 8.0 4.8 7.2 1.8 3.2 1 1 3 4 4 4 0 Heterocyst differentiation regulator C-terminal Hood domain Swi5 PF07061.11 EEQ38515.1 - 2.4 8.3 24.4 3.6 7.8 2.3 3.2 1 1 2 3 3 3 0 Swi5 KxDL PF10241.9 EEQ38515.1 - 2.4 8.5 15.9 1.8 8.9 5.5 2.9 1 1 2 3 3 3 0 Uncharacterized conserved protein Mod_r PF07200.13 EEQ38515.1 - 2.5 8.2 25.6 41 4.3 25.6 2.2 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein UBA_e1_thiolCys PF10585.9 EEQ38515.1 - 2.6 7.9 12.0 3 7.7 12.0 1.2 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site DUF3450 PF11932.8 EEQ38515.1 - 2.6 7.3 23.1 0.95 8.7 7.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) UPF0242 PF06785.11 EEQ38515.1 - 2.7 8.1 28.8 8.1 6.5 18.5 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EEQ38515.1 - 2.9 8.6 20.1 1.2e+03 0.1 20.1 2.2 1 1 0 1 1 1 0 Initiation control protein YabA FAP206 PF12018.8 EEQ38515.1 - 2.9 7.3 13.1 3.2 7.2 9.7 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF16 PF01519.16 EEQ38515.1 - 3 8.4 19.7 3.4 8.2 9.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Fmp27_WPPW PF10359.9 EEQ38515.1 - 3.1 6.6 19.8 6 5.6 19.8 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HIP1_clath_bdg PF16515.5 EEQ38515.1 - 3.1 8.5 26.2 0.88 10.2 20.1 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DASH_Dam1 PF08653.10 EEQ38515.1 - 3.3 7.6 5.2 4.7 7.1 0.5 3.0 1 1 2 3 3 3 0 DASH complex subunit Dam1 LprI PF07007.12 EEQ38515.1 - 3.4 8.4 11.9 5.7 7.6 8.7 2.5 1 1 1 2 2 2 0 Lysozyme inhibitor LprI HisKA_3 PF07730.13 EEQ38515.1 - 3.6 8.2 8.0 6.4 7.4 0.2 3.0 1 1 2 3 3 3 0 Histidine kinase DUF1515 PF07439.11 EEQ38515.1 - 3.8 7.6 6.3 1.1 9.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Seryl_tRNA_N PF02403.22 EEQ38515.1 - 3.9 7.7 24.5 5.8 7.2 14.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 EEQ38515.1 - 4.8 5.7 22.3 7.8 5.0 12.5 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 EEQ38515.1 - 4.8 7.4 26.2 1.2 9.3 4.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Herpes_UL25 PF01499.16 EEQ38515.1 - 4.8 5.6 11.4 0.36 9.3 1.6 2.0 1 1 1 2 2 2 0 Herpesvirus UL25 family MCU PF04678.13 EEQ38515.1 - 4.9 7.2 18.2 1.5 8.9 12.4 2.4 1 1 1 2 2 2 0 Mitochondrial calcium uniporter tRNA_bind_2 PF13725.6 EEQ38515.1 - 5 6.8 17.4 2.1 8.0 15.4 1.4 1 1 1 2 2 2 0 Possible tRNA binding domain V_ATPase_I PF01496.19 EEQ38515.1 - 5.2 4.9 17.8 6.8 4.5 17.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 EEQ38515.1 - 5.2 6.5 14.0 7.3 6.1 14.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit XhlA PF10779.9 EEQ38515.1 - 5.7 7.2 24.0 5.1 7.4 2.0 3.1 1 1 2 3 3 3 0 Haemolysin XhlA HALZ PF02183.18 EEQ38515.1 - 5.8 7.2 20.7 1.5 9.1 0.5 3.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF5595 PF18077.1 EEQ38515.1 - 6.2 7.0 20.5 0.14 12.3 1.6 3.7 2 1 1 3 3 2 0 Domain of unknown function (DUF5595) DASH_Spc19 PF08287.11 EEQ38515.1 - 6.5 6.6 21.2 1.2 9.0 16.2 1.9 1 1 1 2 2 2 0 Spc19 Csm1_N PF18504.1 EEQ38515.1 - 8.6 6.8 25.9 10 6.5 4.0 3.4 1 1 2 3 3 3 0 Csm1 N-terminal domain Atg14 PF10186.9 EEQ38515.1 - 9.4 5.2 22.2 39 3.2 22.3 1.7 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4337 PF14235.6 EEQ38515.1 - 10 6.2 22.1 1.4e+03 -0.8 21.5 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4337) F1F0-ATPsyn_F PF10791.9 EEQ38516.1 - 4.4e-25 88.0 0.0 4.8e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 EEQ38516.1 - 0.021 15.2 0.0 0.021 15.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Pkinase PF00069.25 EEQ38517.1 - 8.6e-68 228.6 0.0 1.7e-62 211.2 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38517.1 - 7.4e-33 113.9 0.0 3.4e-31 108.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EEQ38517.1 - 2.1e-18 65.8 0.2 5.7e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 EEQ38517.1 - 2.6e-05 23.7 0.0 8.7e-05 22.0 0.0 1.9 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 EEQ38517.1 - 0.00011 21.6 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEQ38517.1 - 0.00099 18.1 0.1 0.003 16.6 0.1 1.8 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEQ38517.1 - 0.0044 17.0 0.1 0.046 13.6 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EEQ38517.1 - 0.031 13.8 0.0 0.031 13.8 0.0 1.7 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 EEQ38517.1 - 0.087 11.9 0.0 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 WaaY PF06176.11 EEQ38517.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) DUF4188 PF13826.6 EEQ38518.1 - 0.00072 19.9 0.0 0.0008 19.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) ABM PF03992.16 EEQ38518.1 - 0.0024 17.9 0.0 0.0029 17.7 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3291 PF11695.8 EEQ38518.1 - 0.0051 16.5 0.5 0.014 15.1 0.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3291) Cyclin PF08613.11 EEQ38521.1 - 2.5e-21 76.7 0.8 3.8e-21 76.1 0.3 1.7 2 0 0 2 2 2 1 Cyclin RIBIOP_C PF04950.12 EEQ38522.1 - 4.5e-92 308.6 0.2 4.5e-92 308.6 0.2 2.2 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EEQ38522.1 - 1.3e-29 102.1 0.0 9.8e-29 99.3 0.0 2.7 2 0 0 2 2 1 1 AARP2CN (NUC121) domain AAA_33 PF13671.6 EEQ38522.1 - 1.5e-06 28.4 1.2 3.4e-06 27.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA PF00004.29 EEQ38522.1 - 1.6e-06 28.6 0.1 4.5e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.27 EEQ38522.1 - 3.9e-06 26.5 3.1 0.0012 18.4 0.0 3.1 3 0 0 3 3 2 2 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EEQ38522.1 - 9.2e-06 26.1 0.0 5.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEQ38522.1 - 0.00013 22.3 0.0 0.00042 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ38522.1 - 0.0012 19.2 0.1 0.0037 17.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EEQ38522.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 EEQ38522.1 - 0.0017 18.9 0.1 0.0017 18.9 0.1 4.5 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 EEQ38522.1 - 0.002 18.5 0.0 0.0088 16.4 0.0 2.2 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 EEQ38522.1 - 0.0021 18.0 0.5 0.0053 16.7 0.5 1.7 1 0 0 1 1 1 1 NTPase MMR_HSR1 PF01926.23 EEQ38522.1 - 0.0028 17.7 0.6 0.019 15.0 0.6 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EEQ38522.1 - 0.004 16.9 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EEQ38522.1 - 0.0046 17.2 0.6 0.017 15.4 0.0 2.4 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 EEQ38522.1 - 0.005 16.1 0.9 0.01 15.0 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain Rad17 PF03215.15 EEQ38522.1 - 0.0065 16.4 3.3 0.049 13.6 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_7 PF12775.7 EEQ38522.1 - 0.0094 15.5 0.2 0.021 14.3 0.2 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region MobB PF03205.14 EEQ38522.1 - 0.011 15.6 2.4 0.057 13.3 0.5 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 EEQ38522.1 - 0.012 15.6 0.1 0.036 14.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EEQ38522.1 - 0.015 15.0 0.0 0.041 13.6 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EEQ38522.1 - 0.018 15.5 0.0 0.018 15.5 0.0 2.7 3 0 0 3 3 1 0 ABC transporter AAA_11 PF13086.6 EEQ38522.1 - 0.024 14.4 0.5 0.024 14.4 0.5 4.0 3 2 0 3 3 2 0 AAA domain Macro PF01661.21 EEQ38522.1 - 0.026 14.6 1.6 1 9.5 0.0 2.4 2 0 0 2 2 2 0 Macro domain Zeta_toxin PF06414.12 EEQ38522.1 - 0.033 13.5 7.2 0.068 12.4 0.0 3.6 4 0 0 4 4 4 0 Zeta toxin cobW PF02492.19 EEQ38522.1 - 0.056 13.0 0.1 0.056 13.0 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EEQ38522.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EEQ38522.1 - 0.1 12.6 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EEQ38522.1 - 0.42 10.6 0.0 0.42 10.6 0.0 2.6 3 0 0 3 3 1 0 AAA domain RsgA_GTPase PF03193.16 EEQ38522.1 - 7.4 6.4 5.9 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase TRP PF06011.12 EEQ38524.1 - 5.2e-149 496.6 29.5 6.8e-149 496.2 29.5 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EEQ38524.1 - 7.2e-42 143.0 0.4 1.4e-41 142.1 0.4 1.5 1 0 0 1 1 1 1 ML-like domain Halogen_Hydrol PF10112.9 EEQ38524.1 - 0.22 11.5 2.3 0.75 9.8 0.0 2.9 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein HemY_N PF07219.13 EEQ38524.1 - 1.5 9.0 4.0 5.7 7.2 0.1 3.2 3 0 0 3 3 3 0 HemY protein N-terminus Lon_C PF05362.13 EEQ38525.1 - 2.4e-47 161.2 0.0 4.2e-47 160.3 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EEQ38525.1 - 2e-24 86.5 0.1 3.8e-23 82.4 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 EEQ38525.1 - 3.9e-23 82.4 0.2 3.9e-23 82.4 0.2 2.6 3 1 0 3 3 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA_2 PF07724.14 EEQ38525.1 - 1.2e-07 32.0 0.0 5.1e-07 30.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EEQ38525.1 - 2.8e-07 30.6 0.0 1e-06 28.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EEQ38525.1 - 1.9e-05 24.5 0.0 5.7e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_3 PF07726.11 EEQ38525.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ38525.1 - 0.0002 21.8 0.4 0.00069 20.0 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 EEQ38525.1 - 0.0004 20.2 0.0 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ38525.1 - 0.00068 19.9 0.0 0.073 13.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ38525.1 - 0.002 18.7 0.5 0.0071 16.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EEQ38525.1 - 0.0053 16.9 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EEQ38525.1 - 0.0063 16.5 0.2 0.052 13.5 0.0 2.4 3 0 0 3 3 3 1 Rad17 P-loop domain NB-ARC PF00931.22 EEQ38525.1 - 0.0064 15.7 0.0 0.017 14.3 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.6 EEQ38525.1 - 0.0088 16.1 0.1 0.049 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EEQ38525.1 - 0.012 15.5 1.2 0.043 13.7 0.1 2.5 3 1 1 4 4 2 0 NTPase IstB_IS21 PF01695.17 EEQ38525.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein TsaE PF02367.17 EEQ38525.1 - 0.019 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EEQ38525.1 - 0.021 14.2 0.0 0.12 11.8 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EEQ38525.1 - 0.026 13.7 0.1 0.064 12.4 0.1 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 EEQ38525.1 - 0.033 14.6 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EEQ38525.1 - 0.046 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.6 EEQ38526.1 - 4.7e-15 55.8 0.0 7.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ38526.1 - 4.9e-11 43.1 0.0 3.2e-10 40.5 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ38526.1 - 7e-10 39.5 0.1 3.2e-09 37.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ38526.1 - 1.1e-08 35.0 0.2 7.8e-07 29.0 0.1 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ38526.1 - 2.7e-08 34.4 0.0 7.1e-06 26.6 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ38526.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MNE1 PF13762.6 EEQ38527.1 - 2.8e-42 144.2 4.8 2.8e-42 144.2 4.8 3.7 4 0 0 4 4 4 1 Mitochondrial splicing apparatus component ANAPC3 PF12895.7 EEQ38527.1 - 0.013 15.7 0.9 4.7 7.5 0.1 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Casc1_N PF15927.5 EEQ38527.1 - 0.075 12.7 0.8 0.26 11.0 0.8 1.9 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus U3snoRNP10 PF12397.8 EEQ38527.1 - 0.63 10.4 4.0 1.4e+02 2.8 0.2 4.4 4 0 0 4 4 4 0 U3 small nucleolar RNA-associated protein 10 SET PF00856.28 EEQ38528.1 - 0.12 12.7 0.8 0.17 12.2 0.8 1.4 1 1 0 1 1 1 0 SET domain Ribosomal_L30 PF00327.20 EEQ38529.1 - 8.1e-13 48.1 0.3 1e-12 47.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e HTH_30 PF13556.6 EEQ38529.1 - 0.025 14.4 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 PucR C-terminal helix-turn-helix domain Glyco_trans_1_3 PF13528.6 EEQ38529.1 - 0.07 12.4 0.0 0.078 12.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF413 PF04219.12 EEQ38529.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF EFG_C PF00679.24 EEQ38531.1 - 0.047 13.7 0.0 0.067 13.2 0.0 1.2 1 0 0 1 1 1 0 Elongation factor G C-terminus ADH_N PF08240.12 EEQ38532.1 - 7.8e-26 90.1 0.1 2e-25 88.8 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ38532.1 - 5.7e-24 84.6 0.0 8.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEQ38532.1 - 5.6e-12 45.6 0.0 9e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EEQ38532.1 - 3.8e-05 23.1 0.5 6.6e-05 22.3 0.2 1.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EEQ38532.1 - 0.00015 22.2 0.0 0.0066 17.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ38532.1 - 0.00037 19.8 0.0 0.0017 17.7 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 EEQ38532.1 - 0.0057 17.7 0.0 0.014 16.5 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 EEQ38532.1 - 0.068 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_3 PF03447.16 EEQ38532.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EEQ38532.1 - 0.11 11.8 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EEQ38532.1 - 0.17 10.5 0.6 0.24 10.1 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EEQ38532.1 - 0.19 11.0 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain TPP_enzyme_N PF02776.18 EEQ38534.1 - 1.3e-55 187.6 0.2 4.1e-55 186.0 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EEQ38534.1 - 1e-49 168.2 3.1 4.9e-49 166.0 0.9 3.0 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ38534.1 - 1.7e-37 128.2 0.4 3.8e-37 127.1 0.4 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 EEQ38534.1 - 0.065 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg DUF1788 PF08747.11 EEQ38534.1 - 0.21 11.6 0.0 1.2 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Ammonium_transp PF00909.21 EEQ38535.1 - 4.8e-106 354.8 22.7 5.6e-106 354.6 22.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CheY-binding PF09078.11 EEQ38535.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 CheY binding DUF155 PF02582.14 EEQ38536.1 - 8.5e-40 136.7 0.2 1.2e-39 136.2 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Prefoldin_2 PF01920.20 EEQ38536.1 - 0.3 11.1 3.7 0.79 9.7 0.5 2.7 2 1 1 3 3 3 0 Prefoldin subunit SIS PF01380.22 EEQ38537.1 - 6.7e-65 216.9 0.1 1.3e-33 115.6 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EEQ38537.1 - 5.8e-16 58.9 0.0 1.1e-15 58.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EEQ38537.1 - 3.8e-10 39.8 0.0 7.3e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EEQ38537.1 - 2.4e-05 23.4 0.0 3.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 EEQ38537.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Pkinase PF00069.25 EEQ38538.1 - 1.1e-72 244.6 0.0 1.5e-72 244.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38538.1 - 5.1e-35 121.0 0.0 7e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ38538.1 - 0.00065 19.1 0.1 0.0093 15.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEQ38538.1 - 0.079 11.9 0.1 0.75 8.7 0.0 2.2 2 1 0 2 2 2 0 Haspin like kinase domain RIO1 PF01163.22 EEQ38538.1 - 0.086 12.4 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 EEQ38538.1 - 2.4 6.8 4.1 0.41 9.4 0.1 1.6 2 0 0 2 2 2 0 Fungal protein kinase G-alpha PF00503.20 EEQ38539.1 - 1.8e-106 356.3 3.2 2.3e-106 356.0 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EEQ38539.1 - 6.9e-15 54.9 0.2 6.5e-10 38.7 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ38539.1 - 0.00075 18.9 0.7 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EEQ38539.1 - 0.011 16.0 0.1 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EEQ38539.1 - 0.032 14.0 0.2 0.065 13.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 EEQ38539.1 - 0.15 11.4 0.1 0.35 10.2 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 EEQ38539.1 - 0.15 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Peptidase_M18 PF02127.15 EEQ38541.1 - 2.2e-136 455.1 0.0 2.6e-136 454.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DS PF01916.17 EEQ38542.1 - 4.9e-126 419.8 0.0 5.7e-126 419.6 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase NDUFA12 PF05071.16 EEQ38543.1 - 3.6e-27 95.0 3.9 5e-27 94.6 3.9 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PAP1 PF08601.10 EEQ38544.1 - 1.7e-25 90.5 17.6 2.3e-21 77.0 0.5 2.2 2 0 0 2 2 2 2 Transcription factor PAP1 bZIP_1 PF00170.21 EEQ38544.1 - 4.7e-08 33.0 7.8 9.9e-08 32.0 7.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ38544.1 - 0.0007 19.6 13.3 0.0028 17.7 13.2 2.0 1 1 0 1 1 1 1 Basic region leucine zipper ERM PF00769.19 EEQ38544.1 - 0.0031 17.4 6.1 0.0045 16.8 6.1 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family dsrm PF00035.26 EEQ38544.1 - 0.04 14.6 0.6 0.86 10.4 0.1 2.6 2 0 0 2 2 2 0 Double-stranded RNA binding motif PGBA_C PF15437.6 EEQ38544.1 - 0.093 13.1 9.8 0.24 11.8 9.8 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal KASH_CCD PF14662.6 EEQ38544.1 - 0.21 11.4 4.4 0.36 10.6 4.4 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4140 PF13600.6 EEQ38544.1 - 1.2 9.7 3.5 2.8 8.4 3.5 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_Maf PF03131.17 EEQ38544.1 - 3.1 8.4 11.6 0.46 11.0 7.6 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Mak10 PF04112.13 EEQ38545.1 - 1.2e-29 103.0 0.0 2e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PilZ_2 PF16823.5 EEQ38545.1 - 0.05 13.8 2.5 0.053 13.7 0.5 2.1 2 0 0 2 2 2 0 Atypical PilZ domain, cyclic di-GMP receptor DGF-1_C PF11040.8 EEQ38545.1 - 0.078 13.0 0.0 21 5.2 0.0 2.9 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Cnd3 PF12719.7 EEQ38546.1 - 6.5e-86 288.2 2.9 2.2e-84 283.1 1.5 2.8 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EEQ38546.1 - 3e-11 43.6 1.2 1.6e-07 31.6 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EEQ38546.1 - 3.6e-07 29.9 0.3 0.036 14.3 0.1 5.1 4 0 0 4 4 3 1 HEAT repeat HEAT_EZ PF13513.6 EEQ38546.1 - 1.4e-05 25.5 0.1 2.5 8.7 0.1 4.7 4 0 0 4 4 4 1 HEAT-like repeat Lebercilin PF15619.6 EEQ38546.1 - 5.1e-05 23.0 11.7 5.1e-05 23.0 11.7 1.9 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Cnd1 PF12717.7 EEQ38546.1 - 0.00047 20.2 0.0 0.00047 20.2 0.0 5.3 4 2 0 5 5 4 1 non-SMC mitotic condensation complex subunit 1 FAM184 PF15665.5 EEQ38546.1 - 0.0011 18.8 7.9 0.0011 18.8 7.9 2.3 2 0 0 2 2 2 1 Family with sequence similarity 184, A and B DUF812 PF05667.11 EEQ38546.1 - 0.0013 17.7 9.1 0.0013 17.7 9.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Fez1 PF06818.15 EEQ38546.1 - 0.0034 17.9 4.5 0.0034 17.9 4.5 3.5 2 1 1 3 3 3 2 Fez1 Spc7 PF08317.11 EEQ38546.1 - 0.0059 15.5 15.2 0.0064 15.4 12.8 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein DUF5082 PF16888.5 EEQ38546.1 - 0.0068 16.7 12.2 0.27 11.5 3.7 3.1 1 1 0 2 2 2 2 Domain of unknown function (DUF5082) DUF4795 PF16043.5 EEQ38546.1 - 0.0076 15.9 9.9 0.024 14.3 9.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4795) MscS_porin PF12795.7 EEQ38546.1 - 0.013 15.1 8.2 0.036 13.6 8.2 1.8 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Baculo_PEP_C PF04513.12 EEQ38546.1 - 0.013 15.5 5.0 0.23 11.5 5.1 2.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4200 PF13863.6 EEQ38546.1 - 0.014 15.8 3.9 0.014 15.8 3.9 3.5 3 1 1 4 4 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.19 EEQ38546.1 - 0.03 12.3 16.4 0.0048 14.9 7.6 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Condensin2nSMC PF12422.8 EEQ38546.1 - 0.12 12.6 0.8 0.87 9.8 0.1 2.9 3 1 1 4 4 2 0 Condensin II non structural maintenance of chromosomes subunit ATG16 PF08614.11 EEQ38546.1 - 0.17 12.1 23.4 0.04 14.1 11.2 3.6 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) FlaC_arch PF05377.11 EEQ38546.1 - 0.31 11.5 8.4 4 7.9 2.1 3.8 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Taxilin PF09728.9 EEQ38546.1 - 0.45 9.6 20.8 0.79 8.8 8.2 3.2 2 1 1 3 3 3 0 Myosin-like coiled-coil protein SlyX PF04102.12 EEQ38546.1 - 0.78 10.4 5.0 14 6.4 0.7 3.4 3 0 0 3 3 2 0 SlyX ADIP PF11559.8 EEQ38546.1 - 0.82 9.7 13.2 2.4 8.2 5.5 2.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF3573 PF12097.8 EEQ38546.1 - 0.94 8.2 5.0 1.7 7.4 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Med9 PF07544.13 EEQ38546.1 - 0.97 9.6 9.9 2.2 8.4 7.6 2.8 2 1 0 2 2 1 0 RNA polymerase II transcription mediator complex subunit 9 TMF_TATA_bd PF12325.8 EEQ38546.1 - 1.2 9.4 12.5 13 6.1 11.0 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding CENP-F_leu_zip PF10473.9 EEQ38546.1 - 1.5 8.8 17.3 10 6.1 5.4 3.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EEQ38546.1 - 1.9 8.0 19.4 0.4 10.2 7.7 2.7 2 1 1 3 3 2 0 Intermediate filament protein Cnn_1N PF07989.11 EEQ38546.1 - 2.5 8.3 14.3 0.66 10.2 7.4 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 FlxA PF14282.6 EEQ38546.1 - 2.9 7.9 12.3 13 5.8 10.1 2.7 1 1 1 2 2 2 0 FlxA-like protein DUF4349 PF14257.6 EEQ38546.1 - 3 7.3 6.1 1.1 8.6 3.2 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4349) YscO PF07321.12 EEQ38546.1 - 4.5 7.2 8.1 7.8 6.4 1.0 2.9 2 1 1 3 3 2 0 Type III secretion protein YscO DUF3450 PF11932.8 EEQ38546.1 - 4.8 6.4 11.4 39 3.5 7.5 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Pox_A_type_inc PF04508.12 EEQ38546.1 - 5.1 7.1 9.0 1.7 8.6 4.4 2.8 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF1664 PF07889.12 EEQ38546.1 - 5.2 7.1 10.9 6.2 6.9 6.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 EEQ38546.1 - 6.5 7.1 12.9 6.2 7.2 2.8 3.7 2 1 1 3 3 2 0 ABC transporter C-terminal domain Spc24 PF08286.11 EEQ38546.1 - 7.1 6.9 17.2 19 5.6 4.7 3.9 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 CC2-LZ PF16516.5 EEQ38546.1 - 8.8 6.8 13.2 2 8.8 2.3 3.2 2 1 1 3 3 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF2730 PF10805.8 EEQ38546.1 - 9.2 6.4 7.0 9.4 6.4 2.2 3.0 2 1 1 3 3 2 0 Protein of unknown function (DUF2730) HIP1_clath_bdg PF16515.5 EEQ38546.1 - 9.5 6.9 12.4 41 4.9 8.0 3.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Sterol_MT_C PF08498.10 EEQ38547.1 - 8e-28 96.5 0.3 1.3e-27 95.9 0.3 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EEQ38547.1 - 1.3e-16 61.0 0.0 2.7e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ38547.1 - 9.3e-16 58.3 0.0 2.1e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ38547.1 - 5e-15 55.6 0.0 9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ38547.1 - 3.5e-11 42.9 0.9 5.1e-11 42.4 0.9 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EEQ38547.1 - 1.1e-10 42.1 0.0 2.6e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ38547.1 - 1.2e-10 41.4 0.0 1.8e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ38547.1 - 1.2e-06 28.0 0.0 1.9e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EEQ38547.1 - 0.00064 19.3 0.0 0.002 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_15 PF09445.10 EEQ38547.1 - 0.00099 18.7 0.1 0.0018 17.9 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_29 PF03141.16 EEQ38547.1 - 0.0015 17.2 0.0 0.0021 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 EEQ38547.1 - 0.0015 18.0 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EEQ38547.1 - 0.018 14.1 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EEQ38547.1 - 0.02 14.7 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EEQ38547.1 - 0.031 14.2 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_76 PF03663.14 EEQ38548.1 - 9.7e-41 140.5 1.7 1.2e-40 140.2 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EEQ38548.1 - 4e-06 26.1 0.7 0.1 11.7 0.0 3.0 1 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 EEQ38548.1 - 0.001 18.6 0.1 0.0061 16.1 0.0 2.2 2 0 0 2 2 2 1 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_127 PF07944.12 EEQ38548.1 - 0.0011 17.6 0.1 0.8 8.1 0.0 2.2 1 1 0 2 2 2 2 Beta-L-arabinofuranosidase, GH127 GlcNAc_2-epim PF07221.11 EEQ38548.1 - 0.0072 15.6 0.3 1 8.6 0.0 2.9 1 1 2 3 3 3 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) WD40 PF00400.32 EEQ38549.1 - 1.1e-09 38.7 13.9 0.026 15.4 0.3 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38549.1 - 3.8e-07 30.3 4.3 0.55 10.6 0.0 5.8 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Lgl_C PF08596.10 EEQ38549.1 - 0.018 13.8 0.0 4.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Lethal giant larvae(Lgl) like, C-terminal ACBP PF00887.19 EEQ38550.1 - 2.5e-21 75.7 0.0 4.6e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein EMC3_TMCO1 PF01956.16 EEQ38551.1 - 0.056 13.2 0.0 0.075 12.8 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Ribosomal_L11_N PF03946.14 EEQ38552.1 - 9.4e-22 76.6 0.3 2.1e-21 75.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EEQ38552.1 - 5.5e-17 62.0 0.5 1.3e-16 60.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain RA PF00788.23 EEQ38553.1 - 3.2e-13 50.1 0.0 6.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.17 EEQ38553.1 - 1.8e-06 27.9 0.0 3.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EEQ38553.1 - 0.00025 21.4 0.0 0.0029 18.0 0.0 2.6 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) PLRV_ORF5 PF01690.17 EEQ38553.1 - 0.087 11.5 0.2 0.15 10.8 0.2 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF908 PF06012.12 EEQ38553.1 - 1.1 8.6 6.4 1.4 8.2 6.4 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) Metallophos PF00149.28 EEQ38554.1 - 2.4e-17 64.1 1.3 3.3e-17 63.7 0.0 1.9 2 1 0 2 2 1 1 Calcineurin-like phosphoesterase Coilin_N PF15862.5 EEQ38554.1 - 5.8e-07 29.4 0.0 1.3e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Coilin N-terminus CDC45 PF02724.14 EEQ38554.1 - 0.00025 19.5 23.6 0.00035 19.0 23.6 1.1 1 0 0 1 1 1 1 CDC45-like protein RNA_polI_A34 PF08208.11 EEQ38554.1 - 0.0017 18.5 37.0 0.003 17.7 37.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.17 EEQ38554.1 - 0.014 15.5 2.0 0.023 14.9 2.0 1.3 1 0 0 1 1 1 0 DDHD domain Dsh_C PF12316.8 EEQ38554.1 - 0.064 13.7 1.4 0.12 12.8 1.4 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Merozoite_SPAM PF07133.11 EEQ38554.1 - 0.15 12.0 42.5 0.28 11.2 42.5 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Presenilin PF01080.17 EEQ38554.1 - 0.62 8.8 16.8 0.91 8.2 16.8 1.1 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.12 EEQ38554.1 - 2 8.6 12.6 3.2 8.0 12.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 EEQ38554.1 - 2.5 7.8 28.4 4 7.2 28.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIF_alpha PF05793.12 EEQ38554.1 - 3.2 6.2 44.2 4.5 5.7 44.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Neur_chan_memb PF02932.16 EEQ38554.1 - 6.9 6.7 7.4 11 6.0 7.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop14 PF04147.12 EEQ38554.1 - 7.1 4.7 35.9 9.6 4.3 35.9 1.1 1 0 0 1 1 1 0 Nop14-like family Connexin PF00029.19 EEQ38554.1 - 7.8 6.2 15.4 14 5.3 15.4 1.4 1 0 0 1 1 1 0 Connexin AAA_11 PF13086.6 EEQ38554.1 - 8.1 6.1 14.0 14 5.4 14.0 1.3 1 0 0 1 1 1 0 AAA domain ATP11 PF06644.11 EEQ38554.1 - 8.6 6.1 16.0 15 5.3 16.0 1.3 1 0 0 1 1 1 0 ATP11 protein SpoIIP PF07454.11 EEQ38554.1 - 9.7 5.6 20.0 16 4.8 20.0 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pkinase PF00069.25 EEQ38555.1 - 1.9e-66 224.2 0.0 2.6e-66 223.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38555.1 - 1.3e-49 168.8 0.0 2.1e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EEQ38555.1 - 5.6e-30 103.6 0.1 1e-29 102.8 0.1 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EEQ38555.1 - 1.7e-10 41.2 0.0 4e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EEQ38555.1 - 1.7e-08 34.4 0.0 4.3e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 EEQ38555.1 - 0.00037 19.9 0.0 0.55 9.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EEQ38555.1 - 0.0022 16.8 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RA PF00788.23 EEQ38555.1 - 0.028 15.0 0.1 0.053 14.2 0.1 1.4 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain Pkinase PF00069.25 EEQ38556.1 - 1.7e-16 60.4 0.0 2.6e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38556.1 - 1e-10 41.4 0.0 1.3e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EEQ38557.1 - 6.6e-12 45.4 0.0 4.2e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38557.1 - 0.084 12.1 0.0 0.53 9.5 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase ADH_zinc_N_2 PF13602.6 EEQ38559.1 - 3.1e-13 50.9 0.0 7.4e-13 49.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EEQ38559.1 - 6.1e-10 39.2 0.0 1.1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ38559.1 - 0.0051 16.7 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RmuC PF02646.16 EEQ38559.1 - 0.14 11.3 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 RmuC family Acetyltransf_1 PF00583.25 EEQ38560.1 - 1.7e-12 47.6 0.1 2e-12 47.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ38560.1 - 9.1e-09 35.6 0.1 1.3e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ38560.1 - 2.8e-08 33.7 0.1 3.6e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LacAB_rpiB PF02502.18 EEQ38560.1 - 0.05 13.6 0.5 0.74 9.8 0.1 2.0 2 0 0 2 2 2 0 Ribose/Galactose Isomerase kleA_kleC PF17383.2 EEQ38561.1 - 0.12 12.8 0.6 0.26 11.6 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A Mucin PF01456.17 EEQ38561.1 - 0.98 9.4 15.5 1.6 8.7 15.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SRRM_C PF15230.6 EEQ38562.1 - 3.3 8.3 8.5 0.46 11.1 2.6 2.6 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus Ribosomal_S2 PF00318.20 EEQ38563.1 - 1.6e-24 86.3 0.1 4.3e-13 49.0 0.0 2.3 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EEQ38563.1 - 5.6e-07 30.8 9.0 1.2e-06 29.8 9.0 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus MFS_1 PF07690.16 EEQ38564.1 - 4.9e-17 61.9 39.1 3.8e-13 49.1 27.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.13 EEQ38564.1 - 0.097 13.3 0.8 0.69 10.5 0.0 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Pam17 PF08566.10 EEQ38564.1 - 0.12 12.2 2.3 5.7 6.8 0.2 2.9 2 1 0 2 2 2 0 Mitochondrial import protein Pam17 VirB3 PF05101.13 EEQ38564.1 - 0.74 10.1 5.6 2.2 8.6 0.1 3.8 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein Gpi1 PF05024.15 EEQ38565.1 - 1.4e-54 185.1 1.1 2e-54 184.5 1.1 1.2 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) CTP_transf_like PF01467.26 EEQ38566.1 - 1.2e-32 113.1 0.0 1.8e-32 112.5 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like NDC10_II PF16787.5 EEQ38566.1 - 0.085 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Zn_clus PF00172.18 EEQ38567.1 - 1.9e-08 34.3 31.6 0.00097 19.2 9.9 3.3 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Hamartin PF04388.12 EEQ38567.1 - 0.0047 15.7 3.1 0.0054 15.5 3.1 1.1 1 0 0 1 1 1 1 Hamartin protein Ferric_reduct PF01794.19 EEQ38569.1 - 2.2e-20 73.0 15.1 2.2e-20 73.0 15.1 2.9 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EEQ38569.1 - 3.7e-17 62.4 0.0 9.9e-17 61.0 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Pox_I5 PF04713.12 EEQ38569.1 - 0.21 11.6 2.9 0.64 10.1 1.0 2.5 2 0 0 2 2 2 0 Poxvirus protein I5 CFEM PF05730.11 EEQ38569.1 - 0.41 10.8 2.6 0.78 9.9 2.6 1.3 1 0 0 1 1 1 0 CFEM domain DUF4064 PF13273.6 EEQ38569.1 - 8.8 6.7 14.1 0.4 11.0 0.8 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Aldose_epim PF01263.20 EEQ38570.1 - 8.2e-43 146.8 0.2 1e-42 146.5 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase PAP2_3 PF14378.6 EEQ38571.1 - 1.9e-22 79.9 12.3 1.9e-22 79.9 12.3 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EEQ38571.1 - 1.8e-09 37.5 6.7 1.8e-09 37.5 6.7 2.5 3 0 0 3 3 3 1 PAP2 superfamily Ribosomal_S6 PF01250.17 EEQ38572.1 - 1.4e-27 95.8 0.0 1.7e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 DUF3759 PF12585.8 EEQ38573.1 - 3e-40 136.1 2.7 3.6e-40 135.9 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Serine_protease PF18405.1 EEQ38573.1 - 0.085 12.0 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 Gammaproteobacterial serine protease MutS_V PF00488.21 EEQ38574.1 - 1.6e-77 259.8 0.2 2.9e-77 259.0 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEQ38574.1 - 1.4e-31 110.3 4.1 3.4e-31 109.0 4.1 1.7 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EEQ38574.1 - 4.8e-17 62.1 1.1 1.2e-16 60.8 1.1 1.7 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EEQ38574.1 - 5.8e-12 46.1 3.2 4e-11 43.3 0.8 3.4 2 1 0 2 2 2 1 MutS domain II MutS_I PF01624.20 EEQ38574.1 - 2.3e-08 34.3 0.6 2e-07 31.2 0.4 2.3 2 0 0 2 2 2 1 MutS domain I DUF3899 PF13038.6 EEQ38574.1 - 0.12 12.9 0.6 6 7.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Ceramidase PF05875.12 EEQ38575.1 - 5.6e-95 317.7 10.9 7e-95 317.4 10.9 1.1 1 0 0 1 1 1 1 Ceramidase MerC PF03203.14 EEQ38575.1 - 4.2 7.9 9.1 38 4.8 7.7 2.8 1 1 1 2 2 2 0 MerC mercury resistance protein p450 PF00067.22 EEQ38576.1 - 1.2e-42 146.2 0.0 1.2e-39 136.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 PAPS_reduct PF01507.19 EEQ38577.1 - 1.6e-43 148.7 0.0 2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ca_bind_SSO6904 PF18249.1 EEQ38577.1 - 0.069 13.5 0.1 2 8.8 0.0 2.2 2 0 0 2 2 2 0 Calcium binding protein SSO6904 Parecho_VpG PF06344.11 EEQ38577.1 - 0.14 12.8 0.2 1.3 9.8 0.2 2.4 2 0 0 2 2 2 0 Parechovirus Genome-linked protein Ctr PF04145.15 EEQ38578.1 - 7.2e-36 124.0 1.5 8.8e-36 123.7 1.5 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF2530 PF10745.9 EEQ38578.1 - 5.7 7.3 6.7 32 4.9 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Nas2_N PF18265.1 EEQ38579.1 - 6.2e-20 70.9 0.1 9.9e-20 70.3 0.1 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EEQ38579.1 - 2.7e-08 33.5 0.1 8.3e-08 32.0 0.1 1.9 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EEQ38579.1 - 3.6e-08 33.6 0.0 7.1e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EEQ38579.1 - 4e-05 23.9 0.0 5.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EEQ38579.1 - 9e-05 22.8 0.0 0.00016 21.9 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Urm1 PF09138.11 EEQ38580.1 - 6.4e-32 109.8 0.1 1e-31 109.1 0.1 1.3 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) DDOST_48kD PF03345.14 EEQ38581.1 - 8.3e-103 344.4 0.4 1.9e-101 339.9 0.4 2.1 1 1 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta MFS_Mycoplasma PF07672.13 EEQ38581.1 - 0.038 13.3 0.2 0.066 12.5 0.2 1.4 1 0 0 1 1 1 0 Mycoplasma MFS transporter Prefoldin_2 PF01920.20 EEQ38582.1 - 2.4e-18 66.0 11.4 2.4e-18 66.0 11.4 1.3 2 0 0 2 2 1 1 Prefoldin subunit Prefoldin PF02996.17 EEQ38582.1 - 0.0001 22.2 13.4 0.00095 19.1 2.6 2.2 1 1 0 2 2 2 2 Prefoldin subunit FliD_N PF02465.18 EEQ38582.1 - 0.019 15.7 3.8 0.019 15.7 3.8 2.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Seryl_tRNA_N PF02403.22 EEQ38582.1 - 0.034 14.4 12.0 0.41 10.9 1.9 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sipho_Gp157 PF05565.11 EEQ38582.1 - 0.076 13.0 11.2 0.2 11.7 4.9 2.0 1 1 1 2 2 2 0 Siphovirus Gp157 Rootletin PF15035.6 EEQ38582.1 - 0.08 13.0 11.3 0.15 12.1 11.2 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion YojJ PF10372.9 EEQ38582.1 - 0.084 13.0 4.6 0.17 12.0 0.4 2.5 2 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus FTA4 PF13093.6 EEQ38582.1 - 0.23 11.4 9.0 0.33 10.8 9.0 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Phage_Mu_Gam PF07352.12 EEQ38582.1 - 0.28 11.1 13.0 0.37 10.7 13.0 1.3 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein ZnuA PF01297.17 EEQ38582.1 - 0.5 9.7 5.6 0.41 10.0 1.9 2.0 1 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic Ribosomal_L29 PF00831.23 EEQ38582.1 - 0.51 10.4 8.9 2.7 8.0 1.5 2.5 2 1 0 2 2 2 0 Ribosomal L29 protein GrpE PF01025.19 EEQ38582.1 - 0.54 9.9 12.4 0.94 9.1 12.4 1.4 1 1 0 1 1 1 0 GrpE DHR10 PF18595.1 EEQ38582.1 - 0.56 10.3 16.1 1.6 8.8 7.6 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain MAS20 PF02064.15 EEQ38582.1 - 1.6 8.9 8.8 1.9 8.6 0.7 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor WXG100 PF06013.12 EEQ38582.1 - 1.7 8.9 11.3 1.1 9.5 6.2 2.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG Sulfatase_C PF14707.6 EEQ38582.1 - 3 8.6 6.7 6.7 7.5 1.4 2.0 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase DUF4407 PF14362.6 EEQ38582.1 - 4.2 6.6 9.2 5.3 6.3 9.2 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 EEQ38582.1 - 4.5 7.4 16.2 6.6 6.8 1.8 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3450 PF11932.8 EEQ38582.1 - 5.1 6.3 15.7 0.86 8.8 7.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2968 PF11180.8 EEQ38582.1 - 5.3 6.6 16.7 1.2 8.8 10.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) PRP1_N PF06424.12 EEQ38582.1 - 7.4 7.0 10.6 4.4 7.7 3.2 2.0 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal UPF0242 PF06785.11 EEQ38582.1 - 7.7 6.6 16.0 18 5.4 16.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus KELK PF15796.5 EEQ38582.1 - 8.5 6.9 17.5 6.8 7.2 4.1 2.2 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase LMBR1 PF04791.16 EEQ38582.1 - 9.1 5.1 7.9 9.4 5.0 7.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein ARD PF03079.14 EEQ38584.1 - 8.8e-39 133.2 0.2 1.1e-38 132.9 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EEQ38584.1 - 8.5e-09 35.0 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EEQ38584.1 - 1.3e-06 28.3 0.0 2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EEQ38584.1 - 0.0012 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Cupin Kri1 PF05178.12 EEQ38584.1 - 0.052 14.1 2.0 0.07 13.7 2.0 1.5 1 1 0 1 1 1 0 KRI1-like family Peptidase_M48 PF01435.18 EEQ38585.1 - 9.2e-41 139.8 0.0 1e-40 139.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M48 DUF4971 PF16341.5 EEQ38585.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4971) WD40 PF00400.32 EEQ38586.1 - 8.4e-28 96.1 17.5 1.9e-05 25.3 0.7 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38586.1 - 4e-11 43.1 0.6 0.13 12.6 0.0 5.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ38586.1 - 4.9e-05 23.3 0.1 0.058 13.3 0.1 2.9 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A 6PF2K PF01591.18 EEQ38587.1 - 5.7e-39 133.7 0.0 7.7e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 EEQ38587.1 - 3.6e-12 46.7 0.3 5.9e-12 46.0 0.3 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EEQ38587.1 - 6.3e-07 29.1 0.0 8.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EEQ38587.1 - 0.00021 21.8 0.0 0.00032 21.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EEQ38587.1 - 0.0013 19.1 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ38587.1 - 0.0014 19.1 0.1 0.0021 18.4 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRP54 PF00448.22 EEQ38587.1 - 0.0015 18.2 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain APS_kinase PF01583.20 EEQ38587.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.7 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.6 EEQ38587.1 - 0.0023 18.2 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EEQ38587.1 - 0.0037 16.8 0.1 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EEQ38587.1 - 0.022 14.8 0.0 0.068 13.3 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EEQ38587.1 - 0.024 13.9 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EEQ38587.1 - 0.026 15.0 0.0 0.071 13.6 0.0 1.8 1 1 1 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 EEQ38587.1 - 0.033 14.0 0.0 0.07 12.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 EEQ38587.1 - 0.11 11.5 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 EEQ38587.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Pet127 PF08634.10 EEQ38588.1 - 3.4e-105 351.4 0.7 8.8e-105 350.0 0.7 1.7 1 1 0 1 1 1 1 Mitochondrial protein Pet127 Hap4_Hap_bind PF10297.9 EEQ38589.1 - 2e-08 34.1 7.1 4.2e-08 33.1 7.1 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EEQ38589.1 - 8e-05 22.7 14.7 0.0025 17.9 10.0 2.8 1 1 1 2 2 2 2 bZIP transcription factor dsrm PF00035.26 EEQ38589.1 - 0.058 14.1 0.0 0.51 11.1 0.0 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif NIF PF03031.18 EEQ38590.1 - 7.2e-41 139.5 0.1 1.1e-40 138.9 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CENP-N PF05238.13 EEQ38590.1 - 0.034 13.5 0.3 0.06 12.6 0.3 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Abhydrolase_1 PF00561.20 EEQ38590.1 - 0.15 11.7 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold CDP-OH_P_transf PF01066.21 EEQ38592.1 - 6.1e-11 42.9 0.9 6.1e-11 42.9 0.9 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PH PF00169.29 EEQ38593.1 - 0.0002 21.9 4.9 0.00076 20.0 4.9 2.1 1 1 0 1 1 1 1 PH domain STAG PF08514.11 EEQ38593.1 - 0.28 11.1 2.9 0.77 9.7 0.2 2.9 3 0 0 3 3 3 0 STAG domain DNA_binding_1 PF01035.20 EEQ38596.1 - 7.5e-28 96.5 0.1 1.3e-27 95.8 0.1 1.4 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain PCI PF01399.27 EEQ38597.1 - 0.0054 17.2 2.2 0.01 16.3 0.1 2.6 3 1 0 3 3 3 1 PCI domain TPR_1 PF00515.28 EEQ38597.1 - 0.43 10.5 4.8 0.27 11.1 0.2 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat V-ATPase_C PF03223.15 EEQ38599.1 - 2.2e-110 369.5 4.0 2.5e-110 369.4 4.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C SURF6 PF04935.12 EEQ38600.1 - 3.8e-49 167.2 50.2 3.8e-49 167.2 50.2 2.2 2 0 0 2 2 2 1 Surfeit locus protein 6 DUF3253 PF11625.8 EEQ38600.1 - 0.0032 17.7 0.3 0.011 16.0 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3253) Adaptin_N PF01602.20 EEQ38601.1 - 3.7e-119 398.6 0.2 4.6e-119 398.4 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EEQ38601.1 - 6.3e-16 58.7 0.0 1.4e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EEQ38601.1 - 1.3e-06 28.5 3.9 0.00026 21.1 0.0 4.2 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ38601.1 - 0.0017 18.7 13.8 1.7 9.1 0.0 7.2 5 2 4 9 9 9 1 HEAT repeats MMS19_C PF12460.8 EEQ38601.1 - 0.014 14.5 2.1 0.7 8.9 0.2 3.2 3 0 0 3 3 3 0 RNAPII transcription regulator C-terminal RIX1 PF08167.12 EEQ38601.1 - 0.02 14.6 0.0 0.37 10.5 0.0 2.8 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EEQ38601.1 - 0.12 13.0 0.1 35 5.1 0.0 3.4 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Pro_isomerase PF00160.21 EEQ38602.1 - 1.6e-16 61.0 0.0 1.6e-16 61.0 0.0 2.6 2 2 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S14 PF00253.21 EEQ38603.1 - 1.8e-22 78.8 0.2 4e-22 77.7 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e AMP-binding PF00501.28 EEQ38605.1 - 1.6e-57 195.1 0.1 3.8e-31 108.1 0.0 2.7 2 1 0 2 2 2 2 AMP-binding enzyme CRAL_TRIO PF00650.20 EEQ38607.1 - 3.5e-35 121.1 0.0 6.7e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ38607.1 - 4.8e-07 29.9 0.0 1.4e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEQ38607.1 - 2.9e-05 24.2 0.0 6.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HMG_CoA_synt_C PF08540.10 EEQ38608.1 - 3.2e-106 355.1 4.6 3.9e-106 354.7 4.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EEQ38608.1 - 4.8e-92 306.6 0.7 9.5e-92 305.6 0.7 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Tubulin_C PF03953.17 EEQ38609.1 - 3.6e-49 166.1 0.0 5.5e-49 165.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 EEQ38609.1 - 2.6e-27 96.3 0.0 4.6e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FAD_binding_6 PF00970.24 EEQ38610.1 - 1.8e-30 105.2 0.0 3e-30 104.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EEQ38610.1 - 1e-27 96.9 0.0 1.6e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EEQ38610.1 - 3.7e-06 27.2 0.0 8.4e-05 22.7 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain zf-CCCH PF00642.24 EEQ38611.1 - 2.6e-11 43.1 11.1 7.7e-07 28.9 1.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ38611.1 - 9.8e-07 28.6 15.6 0.00059 19.8 2.7 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EEQ38611.1 - 8.7e-05 23.2 2.5 0.058 14.1 0.2 2.5 2 0 0 2 2 2 2 Torus domain zf-CCCH_4 PF18044.1 EEQ38611.1 - 0.00017 21.3 12.0 0.063 13.1 3.3 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger RRM_1 PF00076.22 EEQ38611.1 - 0.00075 19.3 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3528 PF12045.8 EEQ38611.1 - 0.0034 18.0 0.1 0.0057 17.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3528) zf-CCCH_3 PF15663.5 EEQ38611.1 - 0.0058 16.8 1.6 1.1 9.5 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EEQ38611.1 - 9 6.9 14.5 14 6.3 4.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Cation_efflux PF01545.21 EEQ38613.1 - 4e-40 137.7 11.4 6e-40 137.1 11.4 1.3 1 0 0 1 1 1 1 Cation efflux family SPX PF03105.19 EEQ38613.1 - 0.029 14.3 0.8 0.034 14.1 0.8 1.2 1 0 0 1 1 1 0 SPX domain BORG_CEP PF14957.6 EEQ38613.1 - 0.17 13.0 4.6 0.48 11.6 4.6 1.7 1 0 0 1 1 1 0 Cdc42 effector CLU PF13236.6 EEQ38614.1 - 4.4e-74 249.0 0.0 8.7e-74 248.1 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EEQ38614.1 - 2.2e-47 161.4 3.5 4.5e-47 160.3 0.0 2.9 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EEQ38614.1 - 2.9e-23 81.9 1.1 1.6e-12 47.5 0.0 4.0 2 1 1 4 4 3 3 Tetratricopeptide repeat CLU_N PF15044.6 EEQ38614.1 - 3.3e-20 72.2 0.2 7.9e-20 71.0 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EEQ38614.1 - 2.3e-10 40.0 0.1 0.0003 20.5 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF727 PF05303.12 EEQ38614.1 - 0.00013 22.0 0.0 0.00056 19.9 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 EEQ38614.1 - 0.00013 21.8 0.2 1 9.6 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat DDHD PF02862.17 EEQ38614.1 - 0.00083 19.6 3.7 0.052 13.7 0.8 2.5 2 0 0 2 2 2 1 DDHD domain TPR_1 PF00515.28 EEQ38614.1 - 0.01 15.6 0.8 3.2 7.7 0.0 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat CPSF100_C PF13299.6 EEQ38614.1 - 0.034 14.3 21.1 0.67 10.1 10.3 2.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TPR_8 PF13181.6 EEQ38614.1 - 0.044 14.0 0.2 0.86 10.0 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat Tim54 PF11711.8 EEQ38614.1 - 0.051 12.3 18.2 0.058 12.2 3.3 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 SAPS PF04499.15 EEQ38614.1 - 0.062 12.1 14.3 0.54 9.0 0.5 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DUF45 PF01863.17 EEQ38614.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF45 DUF2052 PF09747.9 EEQ38614.1 - 0.22 11.6 23.9 0.67 10.0 10.9 2.6 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RR_TM4-6 PF06459.12 EEQ38614.1 - 1.4 8.6 30.7 0.78 9.5 11.2 2.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Trypan_PARP PF05887.11 EEQ38614.1 - 2.9 7.9 31.7 0.14 12.2 5.5 3.4 4 0 0 4 4 4 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.14 EEQ38614.1 - 3 6.0 28.5 3.3 5.9 7.3 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF4045 PF13254.6 EEQ38614.1 - 3.4 7.2 36.5 0.55 9.8 7.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4045) RNA_pol_Rpc4 PF05132.14 EEQ38614.1 - 8.9 6.7 27.2 2.3 8.6 6.9 3.1 3 0 0 3 3 3 0 RNA polymerase III RPC4 RPM2 PF08579.11 EEQ38616.1 - 8.9e-26 90.6 5.8 2.7e-25 89.1 0.2 3.8 4 1 1 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) P16-Arc PF04699.14 EEQ38616.1 - 0.0017 18.8 0.2 0.0063 17.0 0.2 2.0 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Mannosyl_trans3 PF11051.8 EEQ38617.1 - 1.1e-64 218.4 0.2 2.4e-64 217.4 0.2 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Nas2_N PF18265.1 EEQ38617.1 - 0.15 12.0 0.8 1.7 8.6 0.0 2.6 2 0 0 2 2 2 0 Nas2 N_terminal domain Adaptin_N PF01602.20 EEQ38618.1 - 1.3e-95 321.0 19.3 1.6e-95 320.6 19.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EEQ38618.1 - 1.4e-45 155.1 0.3 4.2e-45 153.6 0.3 1.9 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EEQ38618.1 - 8.8e-31 106.4 0.0 3e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EEQ38618.1 - 4.9e-15 55.7 0.1 7.6e-08 32.6 0.0 5.3 3 1 2 5 5 5 2 HEAT repeats Cnd1 PF12717.7 EEQ38618.1 - 1.3e-10 41.5 19.3 0.00021 21.4 0.2 5.7 5 1 2 7 7 7 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EEQ38618.1 - 4.1e-05 23.5 8.9 1.1 9.8 0.1 6.7 7 0 0 7 7 7 1 HEAT repeat PAC3 PF10178.9 EEQ38618.1 - 0.026 14.6 0.1 0.12 12.5 0.1 2.1 2 0 0 2 2 2 0 Proteasome assembly chaperone 3 UPF0253 PF06786.12 EEQ38618.1 - 0.071 13.4 0.0 0.74 10.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) FANCI_S2 PF14676.6 EEQ38618.1 - 0.52 10.6 14.0 2.3 8.5 1.1 3.6 3 0 0 3 3 3 0 FANCI solenoid 2 HEAT_EZ PF13513.6 EEQ38618.1 - 1.4 9.5 6.2 5.3 7.7 0.6 3.9 4 1 0 4 4 4 0 HEAT-like repeat CIMR PF00878.18 EEQ38619.1 - 7.1e-11 42.4 0.2 6.5e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EEQ38619.1 - 4.2e-07 29.3 0.0 7.3e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EEQ38619.1 - 0.00034 20.6 0.1 0.00034 20.6 0.1 1.9 2 1 0 2 2 2 1 Autophagy-related protein 27 PRKCSH_1 PF13015.6 EEQ38619.1 - 0.085 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein Cnd1 PF12717.7 EEQ38620.1 - 9.1e-06 25.8 0.9 5.3e-05 23.3 0.6 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 EEQ38620.1 - 3.9e-05 23.2 0.0 8.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain CLASP_N PF12348.8 EEQ38620.1 - 0.0057 16.2 0.5 0.079 12.5 0.2 2.5 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 EEQ38620.1 - 0.0076 16.4 0.0 43 4.8 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Pkinase_Tyr PF07714.17 EEQ38620.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Fungal_trans PF04082.18 EEQ38621.1 - 1.7e-33 115.8 1.2 1.7e-33 115.8 1.2 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ38621.1 - 4.3e-10 39.6 10.0 4.3e-10 39.6 10.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 EEQ38622.1 - 1.3e-169 565.8 48.8 1.6e-169 565.5 48.8 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_3 PF16080.5 EEQ38622.1 - 0.0024 17.6 3.8 0.39 10.5 0.1 3.6 3 0 0 3 3 3 2 Bacteriophage holin family HP1 Solute_trans_a PF03619.16 EEQ38623.1 - 1.5e-80 270.6 9.4 1.8e-80 270.3 9.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha mIF3 PF14877.6 EEQ38624.1 - 3.4e-58 196.2 4.9 3.4e-58 196.2 4.9 1.6 2 0 0 2 2 2 1 Mitochondrial translation initiation factor Fe_hyd_lg_C PF02906.14 EEQ38625.1 - 6.3e-68 229.0 0.0 1.1e-67 228.3 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DIL PF01843.19 EEQ38626.1 - 6.8e-20 71.3 1.5 8.8e-19 67.7 1.2 2.8 2 1 0 2 2 2 1 DIL domain Ank_4 PF13637.6 EEQ38626.1 - 6.4e-07 29.8 0.1 0.0019 18.8 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ38626.1 - 7.6e-07 29.0 0.0 0.00077 19.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EEQ38626.1 - 3.8e-06 27.4 0.0 2.1e-05 25.0 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ38626.1 - 1.2e-05 25.4 0.0 0.00019 21.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EEQ38626.1 - 0.00029 21.1 0.0 0.013 15.9 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ribosomal_L37 PF08561.10 EEQ38627.1 - 8.5e-23 81.1 7.5 9.5e-19 68.1 0.4 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 DUF4342 PF14242.6 EEQ38627.1 - 0.47 10.5 3.3 1.6 8.8 2.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) YchF-GTPase_C PF06071.13 EEQ38628.1 - 2.8e-35 120.3 0.0 7.6e-35 119.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EEQ38628.1 - 5.2e-17 62.0 0.0 2.1e-16 60.0 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EEQ38628.1 - 0.00047 20.1 0.0 0.00099 19.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EEQ38628.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B SecA_PP_bind PF01043.20 EEQ38628.1 - 0.12 13.1 0.6 0.55 10.9 0.1 2.1 2 0 0 2 2 2 0 SecA preprotein cross-linking domain QueH PF02677.14 EEQ38629.1 - 0.019 15.1 0.1 0.024 14.8 0.1 1.1 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH DUF5333 PF17267.2 EEQ38629.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5333) DUF3251 PF11622.8 EEQ38629.1 - 0.18 11.5 2.1 0.36 10.4 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) FHA_2 PF17913.1 EEQ38629.1 - 0.2 11.9 1.1 0.61 10.4 0.5 1.9 1 1 1 2 2 2 0 FHA domain MTCP1 PF08991.10 EEQ38630.1 - 4.3e-28 97.3 10.6 6.2e-28 96.8 10.6 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EEQ38630.1 - 0.047 13.8 6.6 0.047 13.8 6.6 1.6 2 0 0 2 2 2 0 CHCH domain DUF1640 PF07798.11 EEQ38631.1 - 3.2e-33 115.2 9.6 3.2e-33 115.2 9.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Myb_DNA-bind_3 PF12776.7 EEQ38631.1 - 0.2 12.7 2.0 0.96 10.5 0.4 2.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain OPT PF03169.15 EEQ38632.1 - 8e-168 559.9 49.3 9.3e-168 559.6 49.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_3 PF16080.5 EEQ38632.1 - 0.0091 15.7 2.4 2 8.2 0.1 3.1 2 0 0 2 2 2 2 Bacteriophage holin family HP1 DUF4946 PF16304.5 EEQ38633.1 - 0.17 11.6 0.2 0.27 10.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4946) Peptidase_M48 PF01435.18 EEQ38634.1 - 3.2e-30 105.4 0.0 3.9e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 EEQ38634.1 - 0.0048 16.7 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M78 PF06114.13 EEQ38634.1 - 0.14 12.1 0.3 1.9 8.4 0.1 2.1 2 0 0 2 2 2 0 IrrE N-terminal-like domain GDPD PF03009.17 EEQ38635.1 - 4e-74 249.6 0.0 1.1e-73 248.2 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EEQ38635.1 - 2.5e-20 72.9 0.0 1.6e-09 38.2 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) SPX PF03105.19 EEQ38635.1 - 8.1e-16 58.9 22.2 6e-11 42.9 0.2 4.5 3 1 1 4 4 4 4 SPX domain Ank_4 PF13637.6 EEQ38635.1 - 2.1e-14 53.7 0.2 0.0017 18.9 0.0 5.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ38635.1 - 1e-12 47.0 2.4 0.37 11.5 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 EEQ38635.1 - 1.8e-11 44.0 0.6 0.81 10.1 0.0 6.0 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EEQ38635.1 - 3e-09 36.9 0.2 0.12 12.9 0.0 5.4 4 1 0 4 4 4 2 Ankyrin repeat Arginase PF00491.21 EEQ38636.1 - 2.3e-66 224.2 0.0 2.8e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family A_deaminase PF00962.22 EEQ38637.1 - 5.8e-119 397.2 0.1 8.1e-119 396.8 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Phos_pyr_kin PF08543.12 EEQ38638.1 - 2.7e-67 226.7 0.0 3.9e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EEQ38638.1 - 3.7e-36 124.9 0.2 5.1e-36 124.5 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HTH_53 PF18606.1 EEQ38638.1 - 0.15 11.8 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Zap helix turn helix N-terminal domain UPF0175 PF03683.13 EEQ38638.1 - 0.17 11.6 0.3 3.8 7.3 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0175) EF-hand_4 PF12763.7 EEQ38639.1 - 2.8e-22 78.6 0.0 4e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.11 EEQ38639.1 - 9.5e-17 61.2 125.1 9.4e-09 35.6 39.4 12.7 6 4 4 10 10 10 6 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EEQ38639.1 - 2.6e-06 26.6 0.0 0.13 11.9 0.0 3.0 2 0 0 2 2 2 2 EF hand WH2 PF02205.20 EEQ38639.1 - 0.00015 21.4 3.0 0.00053 19.7 0.4 2.8 2 0 0 2 2 2 1 WH2 motif EF-hand_7 PF13499.6 EEQ38639.1 - 0.00031 21.1 0.0 0.56 10.7 0.0 3.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EEQ38639.1 - 0.00097 18.9 0.0 3 8.0 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 EEQ38639.1 - 0.033 14.0 0.1 0.81 9.6 0.0 2.9 3 0 0 3 3 3 0 EF-hand domain pair DUF3287 PF11690.8 EEQ38639.1 - 3.9 7.2 5.5 0.55 10.0 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) AAA_2 PF07724.14 EEQ38640.1 - 2.2e-52 177.6 0.3 3.2e-51 173.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EEQ38640.1 - 1.8e-34 117.8 0.6 1.8e-34 117.8 0.6 2.8 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EEQ38640.1 - 5.5e-27 93.6 0.6 1.8e-26 92.0 0.2 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EEQ38640.1 - 6.1e-19 68.8 0.3 9.5e-10 39.0 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ38640.1 - 1.7e-16 60.5 0.1 8.2e-11 42.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ38640.1 - 3.2e-12 47.2 0.5 0.00035 21.0 0.0 4.5 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EEQ38640.1 - 4.6e-09 36.7 0.7 0.00075 19.8 0.0 3.7 3 2 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EEQ38640.1 - 6.6e-08 32.3 0.1 0.0063 16.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 EEQ38640.1 - 7.4e-08 32.3 0.2 5.6e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_14 PF13173.6 EEQ38640.1 - 3.5e-06 27.1 0.5 0.092 12.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EEQ38640.1 - 3.2e-05 23.7 0.0 0.32 10.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 EEQ38640.1 - 4.3e-05 23.8 0.1 0.6 10.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EEQ38640.1 - 6.8e-05 23.2 0.5 0.54 10.7 0.1 3.6 2 1 0 2 2 2 2 RNA helicase NACHT PF05729.12 EEQ38640.1 - 6.9e-05 22.8 0.2 0.3 11.0 0.0 2.7 3 0 0 3 3 2 2 NACHT domain AAA_30 PF13604.6 EEQ38640.1 - 9.7e-05 22.2 0.4 0.1 12.3 0.0 3.3 3 1 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 EEQ38640.1 - 0.00018 21.5 12.9 0.66 9.9 0.1 4.6 3 2 2 5 5 5 3 ATPase domain predominantly from Archaea TsaE PF02367.17 EEQ38640.1 - 0.00048 20.1 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EEQ38640.1 - 0.00089 18.7 0.1 1.3 8.3 0.0 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EEQ38640.1 - 0.00089 18.6 0.0 0.061 12.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 EEQ38640.1 - 0.001 18.3 2.7 0.16 11.1 0.4 3.7 2 2 0 2 2 2 1 Protein of unknown function (DUF815) DUF853 PF05872.12 EEQ38640.1 - 0.0016 17.2 0.1 0.11 11.1 0.1 2.7 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF853) AAA_19 PF13245.6 EEQ38640.1 - 0.0018 18.6 1.4 0.6 10.4 0.1 3.4 2 1 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EEQ38640.1 - 0.0019 17.9 0.1 0.41 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_6 PF12774.7 EEQ38640.1 - 0.0019 17.2 0.1 0.075 12.0 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region PhoH PF02562.16 EEQ38640.1 - 0.002 17.6 0.1 1.1 8.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein Torsin PF06309.11 EEQ38640.1 - 0.0029 17.7 0.0 0.071 13.2 0.0 2.4 2 0 0 2 2 2 1 Torsin SRP54 PF00448.22 EEQ38640.1 - 0.0034 17.0 0.2 0.83 9.2 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain ResIII PF04851.15 EEQ38640.1 - 0.0037 17.3 4.5 1.9 8.4 0.0 3.6 3 1 1 4 4 3 2 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.9 EEQ38640.1 - 0.0043 16.0 0.1 0.7 8.7 0.1 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 EEQ38640.1 - 0.0046 17.2 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 EEQ38640.1 - 0.0049 16.6 0.0 0.56 9.9 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EEQ38640.1 - 0.0072 16.9 6.3 0.48 11.0 0.2 3.4 3 1 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EEQ38640.1 - 0.0097 16.1 0.1 2.3 8.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EEQ38640.1 - 0.014 15.5 9.0 4.6 7.3 0.0 3.7 3 0 0 3 3 3 0 Helicase HerA, central domain ABC_tran PF00005.27 EEQ38640.1 - 0.023 15.2 3.8 0.71 10.4 0.0 3.5 2 1 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EEQ38640.1 - 0.031 14.2 0.0 12 5.8 0.0 2.9 2 0 0 2 2 2 0 RsgA GTPase Nop16 PF09420.10 EEQ38640.1 - 0.04 14.0 0.0 0.04 14.0 0.0 2.0 2 0 0 2 2 1 0 Ribosome biogenesis protein Nop16 V_ATPase_I PF01496.19 EEQ38640.1 - 0.13 10.2 1.2 0.18 9.7 1.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MMR_HSR1 PF01926.23 EEQ38640.1 - 0.13 12.4 0.0 3.8 7.6 0.0 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase Prefoldin PF02996.17 EEQ38640.1 - 0.43 10.5 7.3 1.6 8.7 0.1 4.5 4 1 0 4 4 4 0 Prefoldin subunit PPR_2 PF13041.6 EEQ38641.1 - 2.3e-11 43.7 5.9 0.0009 19.4 0.1 5.2 3 2 3 6 6 6 3 PPR repeat family PPR PF01535.20 EEQ38641.1 - 3.3e-10 39.5 3.3 0.019 15.2 0.1 5.5 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 EEQ38641.1 - 3.4e-10 39.7 1.3 2.8e-06 26.9 0.2 2.5 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EEQ38641.1 - 1.5e-05 25.0 1.9 0.0017 18.4 0.1 3.9 2 1 2 4 4 4 2 Pentatricopeptide repeat domain Rho_GDI PF02115.17 EEQ38641.1 - 0.0014 18.4 0.6 0.016 15.0 0.1 2.3 2 0 0 2 2 2 1 RHO protein GDP dissociation inhibitor LD_cluster3 PF18180.1 EEQ38641.1 - 0.052 13.2 0.2 0.1 12.2 0.2 1.4 1 0 0 1 1 1 0 SLOG cluster3 family ATP13 PF12921.7 EEQ38641.1 - 0.084 12.7 0.1 0.76 9.6 0.1 2.6 1 1 0 1 1 1 0 Mitochondrial ATPase expression TnsE_C PF18623.1 EEQ38641.1 - 0.29 11.1 3.0 0.66 9.9 0.1 2.5 2 0 0 2 2 2 0 TnsE C-terminal domain NinG PF05766.12 EEQ38641.1 - 0.46 10.4 5.6 5.2 7.0 6.6 2.0 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein tRNA-synt_1_2 PF13603.6 EEQ38642.1 - 1.7e-46 158.1 0.0 3.3e-46 157.1 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 EEQ38642.1 - 3.6e-45 154.3 1.6 1e-17 63.6 0.2 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EEQ38642.1 - 4.4e-25 88.3 0.3 1.9e-18 66.4 0.0 4.8 4 1 1 5 5 5 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEQ38642.1 - 4.8e-13 49.3 0.2 8.7e-13 48.5 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EEQ38642.1 - 0.0006 19.3 0.0 1 8.6 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain DNA_ligase_ZBD PF03119.16 EEQ38642.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Zn-ribbon_8 PF09723.10 EEQ38642.1 - 0.15 12.2 0.5 0.7 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 EEQ38642.1 - 0.34 10.4 3.1 1.1 8.7 0.3 2.4 2 0 0 2 2 2 0 zinc-ribbon domain CLAG PF03805.13 EEQ38643.1 - 0.0056 14.3 0.0 0.0081 13.8 0.0 1.1 1 0 0 1 1 1 1 Cytoadherence-linked asexual protein WD40 PF00400.32 EEQ38644.1 - 1.4e-09 38.4 13.3 1.7e-06 28.7 0.7 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38644.1 - 2e-09 37.6 0.0 0.016 15.5 0.0 4.5 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EEQ38644.1 - 0.0083 15.4 0.1 1.9 7.7 0.0 2.3 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Ge1_WD40 PF16529.5 EEQ38644.1 - 0.091 11.7 0.5 14 4.5 0.1 3.2 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Speriolin_N PF15058.6 EEQ38644.1 - 0.18 11.9 0.4 0.25 11.4 0.4 1.1 1 0 0 1 1 1 0 Speriolin N terminus TMF_DNA_bd PF12329.8 EEQ38645.1 - 0.25 11.4 71.9 0.029 14.4 16.8 6.1 3 1 2 5 5 5 0 TATA element modulatory factor 1 DNA binding Rootletin PF15035.6 EEQ38645.1 - 2.1 8.3 50.5 23 4.9 26.5 2.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Mce4_CUP1 PF11887.8 EEQ38645.1 - 3.2 7.1 7.6 0.91 8.9 1.7 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative SHE3 PF17078.5 EEQ38645.1 - 5.4 6.7 57.6 24 4.5 31.7 3.5 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4349 PF14257.6 EEQ38645.1 - 7.9 5.9 23.1 0.017 14.6 5.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) Epimerase PF01370.21 EEQ38647.1 - 1.9e-17 63.6 0.0 2.5e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ38647.1 - 3e-11 42.8 0.0 4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EEQ38647.1 - 1.5e-08 34.5 0.1 5.5e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EEQ38647.1 - 4.6e-08 32.5 0.0 7.3e-05 22.1 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EEQ38647.1 - 7.9e-06 25.9 0.0 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EEQ38647.1 - 9.3e-05 22.0 0.0 0.00021 20.8 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 EEQ38647.1 - 0.0036 17.9 0.0 0.008 16.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.10 EEQ38647.1 - 0.0095 15.9 0.1 0.2 11.5 0.1 2.4 1 1 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 EEQ38647.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EEQ38647.1 - 0.059 13.4 0.0 0.097 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.6 EEQ38647.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 EEQ38647.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SF1-HH PF16275.5 EEQ38648.1 - 5.1e-35 120.2 0.1 5.1e-35 120.2 0.1 2.3 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EEQ38648.1 - 8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 EEQ38648.1 - 8.3e-06 25.7 0.5 1.4e-05 24.9 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EEQ38648.1 - 0.054 13.5 0.1 0.3 11.1 0.0 2.1 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EEQ38648.1 - 0.25 11.2 2.3 0.52 10.2 2.3 1.5 1 0 0 1 1 1 0 Zinc knuckle MTS PF05175.14 EEQ38649.1 - 3.3e-10 39.8 0.0 4.9e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EEQ38649.1 - 4.4e-05 23.3 0.0 5.9e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EEQ38649.1 - 4.9e-05 22.9 0.0 0.00099 18.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EEQ38649.1 - 6.4e-05 23.6 0.0 0.00023 21.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ38649.1 - 0.00024 21.8 0.0 0.0025 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ38649.1 - 0.00051 19.9 0.0 0.0082 16.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF1269 PF06897.12 EEQ38649.1 - 0.015 15.6 0.0 0.091 13.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Methyltransf_16 PF10294.9 EEQ38649.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.4 2 0 0 2 2 2 0 Lysine methyltransferase DUF938 PF06080.12 EEQ38649.1 - 0.099 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_11 PF08241.12 EEQ38649.1 - 0.12 13.0 0.0 0.96 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Met_10 PF02475.16 EEQ38649.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein GCD14 PF08704.10 EEQ38649.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2002 PF09400.10 EEQ38649.1 - 0.23 11.5 0.0 0.39 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) ubiquitin PF00240.23 EEQ38650.1 - 1e-22 79.7 0.0 1.1e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EEQ38650.1 - 3.6e-13 49.1 0.0 4e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EEQ38650.1 - 0.0068 16.4 0.0 2.9 8.0 0.0 2.0 2 0 0 2 2 2 2 Ubiquitin-like domain TBK1_ULD PF18396.1 EEQ38650.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EEQ38650.1 - 0.034 14.6 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain DUF2407 PF10302.9 EEQ38650.1 - 0.098 13.2 0.0 0.12 13.0 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain TPR_14 PF13428.6 EEQ38651.1 - 1.7e-16 59.5 10.2 0.022 15.6 0.2 10.3 7 2 5 12 12 12 6 Tetratricopeptide repeat Suf PF05843.14 EEQ38651.1 - 1.1e-10 42.0 25.4 6e-05 23.2 1.0 7.1 5 3 0 6 6 6 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EEQ38651.1 - 8.6e-09 35.8 0.0 0.01 16.3 0.0 6.4 7 1 1 8 8 8 1 Tetratricopeptide repeat HAT PF02184.16 EEQ38651.1 - 1.4e-07 31.3 30.2 0.042 13.8 0.0 9.4 9 0 0 9 9 9 3 HAT (Half-A-TPR) repeat TPR_2 PF07719.17 EEQ38651.1 - 0.00022 21.1 0.9 14 6.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ38651.1 - 0.0045 16.8 2.2 8.7 6.4 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ38651.1 - 0.014 15.5 0.0 81 3.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ38651.1 - 0.028 14.1 0.0 15 5.4 0.0 3.7 3 0 0 3 3 3 0 TPR repeat U3_assoc_6 PF08640.11 EEQ38651.1 - 0.074 13.1 0.4 0.074 13.1 0.4 5.4 5 1 1 6 6 6 0 U3 small nucleolar RNA-associated protein 6 NAD_binding_6 PF08030.12 EEQ38652.1 - 1.9e-20 73.6 0.0 3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ38652.1 - 9.9e-20 70.7 0.1 5.4e-19 68.3 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EEQ38652.1 - 1.6e-18 67.1 14.2 7.1e-18 64.9 14.2 2.2 1 0 0 1 1 1 1 Ferric reductase like transmembrane component DUF4405 PF14358.6 EEQ38652.1 - 2.4 8.8 12.5 4.1 8.0 1.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) ParBc PF02195.18 EEQ38653.1 - 2.2e-14 53.5 0.0 2.5e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain FTR1 PF03239.14 EEQ38654.1 - 1.9e-83 280.2 9.7 2.2e-83 279.9 9.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Acetate_kinase PF00871.17 EEQ38654.1 - 0.075 11.7 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Acetokinase family Phage_holin_3_6 PF07332.11 EEQ38654.1 - 0.095 12.8 0.1 0.095 12.8 0.1 3.2 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Amidase_5 PF05382.13 EEQ38654.1 - 0.24 11.3 1.3 1.1 9.2 0.3 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase DUF2721 PF11026.8 EEQ38654.1 - 0.57 10.1 3.7 3.2 7.6 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) SirB PF04247.12 EEQ38654.1 - 4.5 7.4 7.6 0.27 11.3 0.9 2.3 2 1 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF2207 PF09972.9 EEQ38654.1 - 9.4 4.9 10.0 5.3 5.7 0.1 2.4 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Pkinase PF00069.25 EEQ38655.1 - 9.7e-61 205.4 0.0 1.2e-60 205.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38655.1 - 1.2e-28 100.1 0.0 1.7e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ38655.1 - 0.00054 19.4 0.0 0.016 14.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEQ38655.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 EEQ38656.1 - 2.4e-110 369.5 34.3 2.9e-110 369.2 34.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ38656.1 - 9e-29 100.5 38.8 1.3e-27 96.7 31.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Rick_17kDa_Anti PF05433.15 EEQ38656.1 - 0.0048 16.7 2.1 0.013 15.4 2.1 1.7 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EEQ38656.1 - 0.029 14.3 1.1 0.029 14.3 1.1 2.4 2 0 0 2 2 2 0 Glycine zipper Top6b_C PF18000.1 EEQ38656.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain Cytochrom_C1 PF02167.15 EEQ38657.1 - 9.4e-96 319.8 0.0 1.1e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EEQ38657.1 - 0.0013 19.0 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EEQ38657.1 - 0.0042 18.2 0.4 0.01 17.0 0.2 1.8 2 1 0 2 2 2 1 Cytochrome c Cys_Met_Meta_PP PF01053.20 EEQ38658.1 - 1.2e-141 471.7 0.1 1.4e-141 471.5 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EEQ38658.1 - 0.0001 21.8 0.1 0.0086 15.4 0.0 2.5 2 1 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EEQ38658.1 - 0.0016 17.1 0.0 0.0022 16.6 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 EEQ38658.1 - 0.043 13.0 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Cation_ATPase_C PF00689.21 EEQ38659.1 - 1.9e-43 148.3 8.8 1.9e-43 148.3 8.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EEQ38659.1 - 2.3e-25 88.5 0.0 4.4e-25 87.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEQ38659.1 - 1.3e-16 61.6 0.7 5.8e-15 56.2 0.7 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ38659.1 - 4e-11 42.8 0.6 4e-11 42.8 0.6 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEQ38659.1 - 0.00042 20.1 0.6 0.0022 17.8 0.1 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DHODB_Fe-S_bind PF10418.9 EEQ38659.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B COG5 PF10392.9 EEQ38660.1 - 0.00088 19.5 0.8 0.0023 18.1 0.5 1.9 2 1 0 2 2 2 1 Golgi transport complex subunit 5 Spidroin_MaSp PF11260.8 EEQ38660.1 - 0.0042 17.3 4.9 0.011 16.0 0.2 3.0 3 0 0 3 3 3 1 Major ampullate spidroin 1 and 2 Baculo_PEP_C PF04513.12 EEQ38660.1 - 0.0064 16.5 2.5 0.13 12.3 0.5 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3037 PF11236.8 EEQ38660.1 - 0.02 15.3 0.1 1.3 9.5 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) Apolipoprotein PF01442.18 EEQ38660.1 - 0.02 14.8 3.5 0.084 12.7 3.5 1.9 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DASH_Spc34 PF08657.10 EEQ38660.1 - 0.02 14.7 0.8 0.021 14.6 0.1 1.6 2 0 0 2 2 2 0 DASH complex subunit Spc34 Cytochrom_B562 PF07361.11 EEQ38660.1 - 0.035 14.7 0.5 1.2 9.8 0.5 2.4 2 0 0 2 2 2 0 Cytochrome b562 CENP-Q PF13094.6 EEQ38660.1 - 0.092 12.9 5.1 14 5.9 0.1 3.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Not3 PF04065.15 EEQ38660.1 - 0.15 11.4 1.3 0.16 11.4 0.4 1.5 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF4363 PF14276.6 EEQ38660.1 - 0.45 10.7 2.0 20 5.4 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) Uso1_p115_C PF04871.13 EEQ38660.1 - 2.4 8.6 7.8 0.41 11.0 2.8 2.0 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4611 PF15387.6 EEQ38660.1 - 6.1 7.1 8.9 9.2 6.6 2.4 3.1 1 1 1 3 3 3 0 Domain of unknown function (DUF4611) WD40 PF00400.32 EEQ38661.1 - 1.4e-06 28.9 6.8 1.3 10.1 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38661.1 - 2.9e-05 24.3 0.0 0.45 10.9 0.0 4.7 3 1 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 EEQ38661.1 - 0.00024 20.9 1.2 0.031 14.0 0.1 2.8 2 1 0 2 2 2 2 TUP1-like enhancer of split PQQ_3 PF13570.6 EEQ38661.1 - 0.0007 20.0 5.6 0.057 13.9 0.0 3.4 3 0 0 3 3 3 1 PQQ-like domain Mcl1_mid PF12341.8 EEQ38661.1 - 0.03 13.7 0.3 0.097 12.0 0.0 1.9 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Utp8 PF10395.9 EEQ38661.1 - 0.046 12.2 0.0 1.9 6.9 0.0 2.3 3 0 0 3 3 3 0 Utp8 family DUF508 PF04370.12 EEQ38661.1 - 1.3 8.7 5.2 1.5 8.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF508) SCP2 PF02036.17 EEQ38662.1 - 1.1e-23 83.6 4.2 1.3e-23 83.4 4.2 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EEQ38662.1 - 7e-05 23.1 0.4 9.8e-05 22.6 0.4 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Phage_CI_C PF16452.5 EEQ38662.1 - 0.005 17.1 0.5 0.0097 16.2 0.3 1.6 1 1 1 2 2 2 1 Bacteriophage CI repressor C-terminal domain RRT14 PF17075.5 EEQ38663.1 - 1.8e-58 197.9 18.9 2.2e-58 197.7 18.9 1.0 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 AAA_7 PF12775.7 EEQ38663.1 - 0.032 13.7 2.2 0.048 13.2 2.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SurA_N_3 PF13624.6 EEQ38663.1 - 0.034 14.0 3.4 0.039 13.7 1.7 1.8 1 1 1 2 2 2 0 SurA N-terminal domain P-mevalo_kinase PF04275.14 EEQ38663.1 - 0.12 12.3 6.1 0.2 11.6 6.1 1.3 1 0 0 1 1 1 0 Phosphomevalonate kinase RapA_C PF12137.8 EEQ38663.1 - 0.22 10.5 6.7 0.27 10.2 6.7 1.2 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal CSRNP_N PF16019.5 EEQ38663.1 - 0.25 11.2 3.8 0.37 10.7 3.8 1.2 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Prismane PF03063.20 EEQ38663.1 - 0.39 9.3 2.9 0.42 9.2 2.9 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family MMS19_C PF12460.8 EEQ38664.1 - 3.2e-82 276.9 15.1 3.2e-82 276.9 15.1 4.4 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EEQ38664.1 - 3e-73 246.6 4.5 3e-73 246.6 4.5 3.8 4 2 2 6 6 6 1 Dos2-interacting transcription regulator of RNA-Pol-II FeoC PF09012.10 EEQ38664.1 - 0.02 15.0 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator HEAT PF02985.22 EEQ38664.1 - 0.031 14.5 0.4 1e+02 3.6 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.6 EEQ38664.1 - 0.034 14.6 1.4 15 6.3 0.0 5.4 7 1 1 8 8 8 0 HEAT-like repeat Ipi1_N PF12333.8 EEQ38664.1 - 0.091 13.4 7.0 7.3 7.3 0.1 5.0 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation CLASP_N PF12348.8 EEQ38664.1 - 1.9 8.0 14.5 7.3 6.1 0.1 5.2 4 1 2 6 6 6 0 CLASP N terminal MOR2-PAG1_N PF14222.6 EEQ38665.1 - 1.2e-79 268.8 4.4 1.4e-79 268.5 4.4 1.0 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.6 EEQ38666.1 - 0.0005 17.9 0.2 0.00055 17.7 0.2 1.0 1 0 0 1 1 1 1 Cell morphogenesis central region MOR2-PAG1_C PF14225.6 EEQ38667.1 - 2.2e-72 243.9 0.2 3.5e-72 243.3 0.0 1.4 2 0 0 2 2 2 1 Cell morphogenesis C-terminal DFRP_C PF16543.5 EEQ38670.1 - 1.6e-22 79.8 8.1 1.6e-22 79.8 8.1 4.7 4 1 1 5 5 5 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EEQ38670.1 - 7.6e-06 25.7 1.4 7.6e-06 25.7 1.4 2.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ38670.1 - 8.7e-06 25.6 5.5 8.7e-06 25.6 5.5 3.0 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 EEQ38670.1 - 5.7e-05 22.8 2.0 5.7e-05 22.8 2.0 3.0 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 EEQ38670.1 - 0.00081 20.1 7.4 0.00081 20.1 7.4 4.3 3 1 1 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 EEQ38670.1 - 0.0015 18.7 3.6 0.027 14.7 0.4 2.7 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EEQ38670.1 - 0.6 10.7 15.4 0.25 11.9 3.9 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF2183 PF09949.9 EEQ38671.1 - 3.2e-31 107.6 0.0 6.4e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) SH3_1 PF00018.28 EEQ38672.1 - 1.3e-24 85.5 0.7 6.3e-13 48.1 0.1 2.5 2 0 0 2 2 2 2 SH3 domain FCH PF00611.23 EEQ38672.1 - 1e-23 83.4 0.4 4.2e-23 81.4 0.1 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EEQ38672.1 - 2.3e-21 75.4 2.3 2.1e-11 43.5 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 EEQ38672.1 - 2.8e-13 49.3 0.0 1.9e-08 33.8 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 EEQ38672.1 - 0.001 19.1 0.0 0.58 10.3 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_3 PF08239.11 EEQ38672.1 - 0.0054 17.0 0.4 0.017 15.4 0.1 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain RIG-I_C PF18119.1 EEQ38672.1 - 0.062 13.3 0.2 0.062 13.3 0.2 3.0 4 0 0 4 4 4 0 RIG-I receptor C-terminal domain Ribosomal_S7e PF01251.18 EEQ38673.1 - 2.3e-79 265.4 0.8 2.6e-79 265.3 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Rib_5-P_isom_A PF06026.14 EEQ38674.1 - 2e-59 200.1 0.0 2.6e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EEQ38674.1 - 0.00075 19.5 0.1 0.48 10.3 0.0 2.2 1 1 1 2 2 2 2 DeoR C terminal sensor domain DUF5385 PF17359.2 EEQ38675.1 - 0.034 13.7 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) ASFV_J13L PF05568.11 EEQ38675.1 - 0.074 12.8 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein Arf PF00025.21 EEQ38676.1 - 2.3e-63 212.8 0.0 2.5e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEQ38676.1 - 9.6e-16 58.1 0.1 1.3e-15 57.7 0.1 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEQ38676.1 - 9.7e-13 48.0 0.0 1.1e-12 47.8 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEQ38676.1 - 1.7e-12 47.2 1.9 3.2e-09 36.4 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EEQ38676.1 - 1.5e-11 44.0 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EEQ38676.1 - 5.6e-09 35.7 0.0 7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ38676.1 - 1.6e-05 24.9 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 EEQ38676.1 - 0.0045 16.9 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 EEQ38676.1 - 0.027 14.0 0.2 0.45 10.0 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF4871 PF16167.5 EEQ38676.1 - 0.055 13.5 0.3 0.1 12.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4871) 6PF2K PF01591.18 EEQ38676.1 - 0.17 11.2 0.2 0.3 10.3 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase OB_NTP_bind PF07717.16 EEQ38677.1 - 2.1e-24 85.7 0.0 6.9e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EEQ38677.1 - 2e-19 69.8 1.3 3.6e-19 69.1 0.0 2.1 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ38677.1 - 5.1e-12 46.1 0.0 1.3e-11 44.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ38677.1 - 6.4e-09 35.8 0.2 1.1e-08 35.0 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ38677.1 - 1.3e-05 25.5 0.0 4.5e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EEQ38677.1 - 0.00015 21.5 0.1 0.00038 20.1 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 EEQ38677.1 - 0.00051 19.8 0.0 0.00091 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ38677.1 - 0.002 18.5 0.1 0.0041 17.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EEQ38677.1 - 0.0065 16.4 0.1 0.013 15.5 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_23 PF13476.6 EEQ38677.1 - 0.022 15.3 0.3 0.091 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EEQ38677.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EEQ38677.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC1 PF03109.16 EEQ38678.1 - 3.4e-30 104.7 0.0 6.8e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family UPRTase PF14681.6 EEQ38678.1 - 0.048 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase FUSC_2 PF13515.6 EEQ38679.1 - 2e-33 115.2 6.1 2e-33 115.2 6.1 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EEQ38679.1 - 2e-10 40.9 2.6 3.6e-10 40.1 0.2 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 EEQ38679.1 - 1.2e-05 24.1 0.5 0.00013 20.7 0.1 2.3 2 0 0 2 2 2 1 Fusaric acid resistance protein family Cation_ATPase_C PF00689.21 EEQ38679.1 - 1.2 8.8 13.2 0.068 12.9 2.4 2.9 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus Mito_carr PF00153.27 EEQ38680.1 - 3.2e-64 212.9 2.2 2.7e-22 78.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EEQ38680.1 - 2.8e-24 85.3 11.6 3.3e-13 49.9 2.4 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EEQ38680.1 - 6.3e-22 75.4 16.4 1.5e-05 24.2 0.3 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EEQ38680.1 - 1.3e-19 68.4 16.7 9.2e-05 22.1 0.1 4.7 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EEQ38680.1 - 2.2e-15 56.2 7.4 2.6e-09 36.8 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EEQ38680.1 - 2.9e-11 42.3 13.2 0.0028 17.1 0.2 4.7 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 EEQ38680.1 - 0.00039 20.7 1.7 0.69 10.2 0.1 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EEQ38680.1 - 0.00074 19.8 0.6 0.39 11.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain p25-alpha PF05517.12 EEQ38680.1 - 0.00081 19.6 2.9 2.3 8.4 0.0 3.3 1 1 1 3 3 3 2 p25-alpha EF-hand_13 PF17958.1 EEQ38680.1 - 0.0037 17.0 0.2 15 5.4 0.0 3.5 2 1 1 3 3 3 0 EF-hand domain SinI PF08671.10 EEQ38680.1 - 0.66 9.8 6.2 15 5.5 0.1 3.7 4 0 0 4 4 4 0 Anti-repressor SinI Dockerin_1 PF00404.18 EEQ38680.1 - 2.8 8.2 5.0 59 4.0 3.2 3.1 2 1 0 2 2 2 0 Dockerin type I domain HORMA PF02301.18 EEQ38681.1 - 9.7e-06 25.3 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 HORMA domain DUF4174 PF13778.6 EEQ38681.1 - 0.056 13.9 0.0 1.8 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) MENTAL PF10457.9 EEQ38681.1 - 0.075 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Cholesterol-capturing domain DUF559 PF04480.12 EEQ38681.1 - 0.11 12.3 0.0 0.92 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF559) MutL_C PF08676.11 EEQ38682.1 - 8e-29 100.3 0.0 2e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EEQ38682.1 - 1.1e-22 79.9 0.0 2.4e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EEQ38682.1 - 3.1e-12 46.5 0.4 3.1e-12 46.5 0.4 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EEQ38682.1 - 3.6e-07 30.7 0.2 8.1e-07 29.5 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mpp10 PF04006.12 EEQ38682.1 - 0.93 7.9 64.4 1.5 7.2 64.4 1.2 1 0 0 1 1 1 0 Mpp10 protein Zn_clus PF00172.18 EEQ38683.1 - 5.1e-08 32.9 8.0 1.2e-07 31.7 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_C_asm PF01578.20 EEQ38683.1 - 0.0018 18.1 0.1 0.0034 17.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C assembly protein PikAIV_N PF18605.1 EEQ38683.1 - 2.1 8.0 6.1 10 5.8 3.0 2.6 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain PLD_C PF12357.8 EEQ38685.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase D C terminal Zn_clus PF00172.18 EEQ38687.1 - 6e-08 32.7 7.5 1.4e-07 31.5 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain N2227 PF07942.12 EEQ38688.1 - 1.8e-81 273.3 0.0 2.2e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 EEQ38688.1 - 6.1e-07 29.4 0.2 2.5e-06 27.4 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ38688.1 - 0.046 14.5 0.1 0.52 11.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ38688.1 - 0.076 13.7 0.6 0.89 10.2 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Ras PF00071.22 EEQ38689.1 - 1.1e-58 197.4 0.1 1.2e-58 197.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ38689.1 - 1.5e-34 118.8 0.0 2.1e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ38689.1 - 2.7e-14 53.0 0.0 3.1e-14 52.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ38689.1 - 2.5e-05 23.8 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ38689.1 - 3.9e-05 23.7 0.0 6.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ38689.1 - 0.00015 22.2 0.0 0.00019 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EEQ38689.1 - 0.00029 20.8 0.0 0.68 9.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EEQ38689.1 - 0.0003 20.4 0.0 0.00061 19.4 0.0 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Phage_sheath_1N PF17481.2 EEQ38689.1 - 0.054 14.0 0.6 0.091 13.3 0.5 1.6 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain NMT1 PF09084.11 EEQ38690.1 - 3.2e-18 66.5 0.0 1.1e-11 45.1 0.0 2.1 2 0 0 2 2 2 2 NMT1/THI5 like Phosphonate-bd PF12974.7 EEQ38690.1 - 0.00024 20.8 0.0 0.00035 20.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1_2 PF13379.6 EEQ38690.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family SBP_bac_3 PF00497.20 EEQ38690.1 - 0.0034 16.9 0.0 0.0079 15.6 0.0 1.7 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 DUF3834 PF12916.7 EEQ38690.1 - 0.0076 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3834) Malate_synthase PF01274.22 EEQ38691.1 - 4.3e-210 698.4 0.0 5e-210 698.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Y_phosphatase PF00102.27 EEQ38692.1 - 3.8e-52 177.2 0.0 1.5e-44 152.3 0.0 2.1 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EEQ38692.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 EEQ38692.1 - 0.083 12.7 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain KH_1 PF00013.29 EEQ38693.1 - 3.4e-09 36.4 0.0 5.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KH domain HSP70 PF00012.20 EEQ38694.1 - 1e-228 760.4 10.3 1.2e-228 760.3 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ38694.1 - 8.2e-17 61.0 0.5 3.5e-15 55.7 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein ATP-synt_DE PF00401.20 EEQ38694.1 - 0.0002 21.5 1.8 0.0027 17.9 0.4 2.8 2 0 0 2 2 2 1 ATP synthase, Delta/Epsilon chain, long alpha-helix domain FGGY_C PF02782.16 EEQ38694.1 - 0.0032 17.2 0.0 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EEQ38694.1 - 0.083 12.4 1.8 10 5.5 0.0 2.9 3 1 0 3 3 3 0 BadF/BadG/BcrA/BcrD ATPase family NAD-GH PF10712.9 EEQ38695.1 - 6.8e-209 695.1 33.3 7.8e-209 694.9 33.3 1.0 1 0 0 1 1 1 1 NAD-specific glutamate dehydrogenase RIO1 PF01163.22 EEQ38696.1 - 1.3e-42 145.6 1.6 2.7e-42 144.5 1.6 1.6 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EEQ38696.1 - 2.2e-31 107.9 0.2 6e-31 106.5 0.1 1.9 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.23 EEQ38696.1 - 0.00015 21.7 1.3 0.94 9.3 1.7 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EEQ38696.1 - 0.00035 20.0 0.5 0.091 12.1 0.2 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family NOA36 PF06524.12 EEQ38696.1 - 3.1 7.0 12.4 4.6 6.5 12.4 1.2 1 0 0 1 1 1 0 NOA36 protein DUF4148 PF13663.6 EEQ38697.1 - 0.64 10.3 4.2 0.16 12.2 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) DCP2 PF05026.13 EEQ38699.1 - 1.8e-27 95.4 0.0 3.6e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EEQ38699.1 - 7e-14 52.0 0.0 1.6e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain ATP-synt_10 PF05176.14 EEQ38700.1 - 1.7e-91 306.1 0.1 1.9e-91 305.9 0.1 1.0 1 0 0 1 1 1 1 ATP10 protein PQQ PF01011.21 EEQ38700.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat YtfJ_HI0045 PF09695.10 EEQ38700.1 - 0.042 13.5 0.0 0.099 12.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) Ribosomal_S10 PF00338.22 EEQ38701.1 - 2.2e-26 91.9 0.9 2.7e-26 91.7 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e fn3_5 PF06280.12 EEQ38701.1 - 0.097 13.4 2.2 0.18 12.5 0.4 1.9 1 1 1 2 2 2 0 Fn3-like domain Ribosomal_L17 PF01196.19 EEQ38701.1 - 0.11 13.4 0.8 0.16 12.9 0.8 1.3 1 1 0 1 1 1 0 Ribosomal protein L17 PP2C PF00481.21 EEQ38704.1 - 6e-38 130.9 0.0 1.3e-37 129.8 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 EEQ38704.1 - 0.079 12.9 0.0 0.86 9.5 0.0 2.4 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) Ski2_N PF17911.1 EEQ38705.1 - 9.7e-35 119.3 0.2 1.7e-34 118.5 0.2 1.4 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 EEQ38705.1 - 8.2e-20 71.3 0.0 1.4e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EEQ38705.1 - 6e-07 29.6 0.1 1e-06 28.9 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2959 PF11172.8 EEQ38705.1 - 0.02 15.0 0.2 0.047 13.8 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) DSHCT PF08148.12 EEQ38707.1 - 1.7e-48 164.4 0.2 4e-48 163.2 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EEQ38707.1 - 8.4e-21 75.1 8.3 8.4e-21 75.1 8.3 1.8 2 0 0 2 2 2 1 rRNA-processing arch domain Helicase_C PF00271.31 EEQ38707.1 - 2e-07 31.4 0.2 2.4e-06 27.8 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA PF00004.29 EEQ38709.1 - 1.1e-85 284.7 0.0 2.1e-41 141.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ38709.1 - 1.8e-20 72.4 9.7 1.3e-09 37.7 1.8 3.5 4 0 0 4 4 3 2 AAA+ lid domain AAA_16 PF13191.6 EEQ38709.1 - 9e-13 48.9 2.1 1.9e-06 28.3 0.0 4.5 2 1 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.12 EEQ38709.1 - 2.1e-12 47.1 0.0 2.7e-05 24.0 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEQ38709.1 - 4.2e-10 39.8 0.1 0.00035 20.6 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ38709.1 - 3.2e-08 33.9 0.0 0.0069 16.5 0.0 3.3 3 2 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EEQ38709.1 - 8.1e-08 32.5 0.0 0.0026 17.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEQ38709.1 - 1.2e-07 32.1 0.6 0.0024 18.1 0.0 4.4 2 2 1 3 3 3 1 AAA domain TIP49 PF06068.13 EEQ38709.1 - 2.2e-06 27.1 0.0 0.03 13.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain Rad17 PF03215.15 EEQ38709.1 - 1.1e-05 25.4 0.0 0.034 14.0 0.0 2.5 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_14 PF13173.6 EEQ38709.1 - 1.4e-05 25.1 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 EEQ38709.1 - 3.4e-05 23.9 0.6 0.00027 21.1 0.0 2.7 3 0 0 3 3 2 1 Cell division protein 48 (CDC48), N-terminal domain Mg_chelatase PF01078.21 EEQ38709.1 - 6.4e-05 22.4 0.4 0.12 11.7 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EEQ38709.1 - 0.00015 22.1 0.0 0.78 10.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.6 EEQ38709.1 - 0.00017 21.9 0.0 0.78 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EEQ38709.1 - 0.00022 21.2 0.0 0.063 13.3 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EEQ38709.1 - 0.00031 20.7 0.0 0.024 14.5 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_11 PF13086.6 EEQ38709.1 - 0.00054 19.8 0.0 0.085 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EEQ38709.1 - 0.00087 19.2 0.2 0.046 13.6 0.0 3.4 4 1 1 5 5 5 1 NACHT domain AAA_3 PF07726.11 EEQ38709.1 - 0.00092 19.1 0.0 2.2 8.1 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 EEQ38709.1 - 0.0013 18.5 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.6 EEQ38709.1 - 0.0018 17.9 6.2 0.95 9.0 0.0 4.1 2 2 2 4 4 4 1 AAA domain AAA_7 PF12775.7 EEQ38709.1 - 0.0023 17.5 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 EEQ38709.1 - 0.0063 17.1 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EEQ38709.1 - 0.0067 16.2 0.0 0.3 10.8 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EEQ38709.1 - 0.014 15.9 0.0 0.33 11.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 EEQ38709.1 - 0.017 14.9 0.0 0.44 10.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EEQ38709.1 - 0.03 14.6 0.1 0.25 11.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EEQ38709.1 - 0.033 13.3 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EEQ38709.1 - 0.035 13.4 0.1 3 7.1 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 EEQ38709.1 - 0.037 13.7 0.0 17 5.1 0.0 3.7 3 1 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 EEQ38709.1 - 0.077 12.3 0.0 9.3 5.5 0.0 2.7 2 0 0 2 2 2 0 KaiC Sigma54_activ_2 PF14532.6 EEQ38709.1 - 0.077 13.1 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 EEQ38709.1 - 0.13 11.9 0.0 0.13 11.9 0.0 3.3 4 1 0 4 4 3 0 AAA domain TniB PF05621.11 EEQ38709.1 - 0.14 11.6 0.0 12 5.3 0.0 2.7 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 EEQ38709.1 - 0.14 12.1 0.0 1.5 8.7 0.0 2.6 2 2 1 3 3 3 0 NTPase Av_adeno_fibre PF06536.11 EEQ38710.1 - 0.041 13.8 0.8 41 4.1 0.1 3.2 3 0 0 3 3 3 0 Avian adenovirus fibre, N-terminal Pex19 PF04614.12 EEQ38712.1 - 6.5e-64 216.0 10.0 6.5e-64 216.0 10.0 1.5 1 1 1 2 2 2 1 Pex19 protein family GET2 PF08690.10 EEQ38712.1 - 0.0059 16.3 13.7 0.011 15.4 13.7 1.6 1 1 0 1 1 1 1 GET complex subunit GET2 TraI_2 PF07514.11 EEQ38712.1 - 0.039 12.9 0.0 0.092 11.7 0.0 1.5 1 1 1 2 2 2 0 Putative helicase DNA_pol_viral_N PF00242.17 EEQ38712.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain ApoLp-III PF07464.11 EEQ38712.1 - 0.52 10.4 9.4 1.1 9.4 7.5 2.5 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) CDC37_N PF03234.14 EEQ38712.1 - 4.7 8.1 7.9 3.8 8.4 5.5 2.0 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding UQ_con PF00179.26 EEQ38713.1 - 1.2e-43 148.1 0.1 1.5e-43 147.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ38713.1 - 0.0075 16.0 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEQ38713.1 - 0.088 13.1 0.8 0.26 11.6 0.8 1.9 1 1 0 1 1 1 0 RWD domain 6PF2K PF01591.18 EEQ38716.1 - 1.3e-81 273.2 0.1 1.9e-81 272.6 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEQ38716.1 - 7.6e-37 126.9 0.0 1.1e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EEQ38716.1 - 8.5e-05 22.7 0.0 0.00017 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EEQ38716.1 - 0.00097 18.7 0.0 0.0024 17.4 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Peptidase_S64 PF08192.11 EEQ38717.1 - 2.4e-254 846.1 9.9 5e-254 845.0 9.9 1.5 1 1 0 1 1 1 1 Peptidase family S64 DUF3102 PF11300.8 EEQ38717.1 - 0.069 13.4 0.2 0.55 10.5 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3102) Flocculin_t3 PF13928.6 EEQ38718.1 - 0.008 16.7 6.3 0.008 16.7 6.3 3.4 1 1 2 3 3 3 2 Flocculin type 3 repeat Rrp15p PF07890.12 EEQ38721.1 - 1.3e-32 113.0 13.2 1.3e-32 113.0 13.2 2.5 2 1 0 2 2 2 1 Rrp15p MFS_1 PF07690.16 EEQ38722.1 - 3.3e-24 85.5 35.3 3e-17 62.6 8.4 2.5 1 1 2 3 3 3 3 Major Facilitator Superfamily MMPL PF03176.15 EEQ38722.1 - 0.055 12.4 6.3 0.099 11.6 6.3 1.3 1 0 0 1 1 1 0 MMPL family SGS PF05002.15 EEQ38723.1 - 1.1e-28 99.1 2.5 1.1e-28 99.1 2.5 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.16 EEQ38723.1 - 2.5e-15 57.2 0.3 5e-15 56.3 0.3 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 EEQ38723.1 - 3.1e-10 39.4 6.6 0.0011 18.8 1.6 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ38723.1 - 9.9e-10 37.8 7.5 0.044 13.9 1.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ38723.1 - 1.3e-08 35.0 0.7 6.7e-08 32.7 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ38723.1 - 8.6e-05 23.0 2.0 0.0045 17.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ38723.1 - 0.00027 21.5 4.6 0.0043 17.7 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ38723.1 - 0.0024 17.9 4.1 0.71 10.2 0.6 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ38723.1 - 0.0028 17.3 1.5 0.51 10.1 0.1 2.6 2 0 0 2 2 2 2 TPR repeat TPR_6 PF13174.6 EEQ38723.1 - 0.11 13.2 2.1 2 9.2 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ38723.1 - 0.18 12.7 2.8 20 6.4 0.0 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat AMPK1_CBM PF16561.5 EEQ38724.1 - 4.2e-10 39.7 0.0 7e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Ribosomal_60s PF00428.19 EEQ38724.1 - 0.17 12.5 9.4 0.5 11.0 9.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tim54 PF11711.8 EEQ38724.1 - 2.3 6.9 6.3 3.9 6.2 6.3 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PTPS_related PF10131.9 EEQ38725.1 - 0.11 10.8 0.1 0.13 10.5 0.1 1.0 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein Prok-E2_C PF14459.6 EEQ38725.1 - 0.2 11.8 3.3 0.28 11.4 2.3 1.6 1 1 1 2 2 2 0 Prokaryotic E2 family C SRP9-21 PF05486.12 EEQ38726.1 - 9.6e-16 58.0 0.0 9.6e-16 58.0 0.0 2.2 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Nramp PF01566.18 EEQ38727.1 - 2.7e-91 306.2 7.8 9.2e-54 182.8 1.1 2.2 2 0 0 2 2 2 2 Natural resistance-associated macrophage protein Biotin_lipoyl PF00364.22 EEQ38728.1 - 4.1e-20 71.4 0.2 7.6e-20 70.5 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EEQ38728.1 - 1.1e-06 28.9 0.0 2.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain DUF1631 PF07793.11 EEQ38728.1 - 0.061 11.7 1.4 0.087 11.2 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Biotin_lipoyl_2 PF13533.6 EEQ38728.1 - 0.083 12.7 0.0 1.9 8.4 0.0 2.9 3 1 0 3 3 3 0 Biotin-lipoyl like AT_hook PF02178.19 EEQ38729.1 - 2.1 8.5 29.0 0.63 10.1 3.7 3.7 3 0 0 3 3 3 0 AT hook motif TFIIIC_delta PF12657.7 EEQ38730.1 - 1.2e-15 57.9 0.0 3.7e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EEQ38730.1 - 1.7e-06 27.9 0.0 2.5e-05 24.2 0.0 2.6 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex WAPL PF07814.13 EEQ38730.1 - 0.014 14.2 0.1 0.042 12.6 0.1 1.7 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin KaiA PF07688.12 EEQ38730.1 - 0.1 12.7 0.1 0.29 11.3 0.1 1.7 1 0 0 1 1 1 0 KaiA C-terminal domain EI24 PF07264.11 EEQ38731.1 - 0.00084 19.6 10.9 0.013 15.7 1.0 2.5 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Bap31 PF05529.12 EEQ38731.1 - 3.4 7.5 9.5 2.2 8.2 2.2 2.7 3 0 0 3 3 3 0 Bap31/Bap29 transmembrane region PALP PF00291.25 EEQ38732.1 - 4.4e-61 206.9 0.0 5.3e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PEP_mutase PF13714.6 EEQ38732.1 - 0.044 13.2 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase PrpR_N PF06506.11 EEQ38732.1 - 0.16 11.5 0.2 1.6 8.2 0.0 2.4 2 1 0 2 2 2 0 Propionate catabolism activator Helicase_C_2 PF13307.6 EEQ38733.1 - 4.5e-56 189.7 0.1 1e-55 188.5 0.1 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 EEQ38733.1 - 2.5e-47 160.8 1.6 4.8e-47 159.8 1.6 1.5 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 EEQ38733.1 - 3.1e-07 30.5 0.5 0.00078 19.5 0.0 2.8 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit HBB PF06777.11 EEQ38733.1 - 0.00064 19.5 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Helical and beta-bridge domain DEAD PF00270.29 EEQ38733.1 - 0.0033 17.2 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase SNF2_N PF00176.23 EEQ38733.1 - 0.095 11.4 0.5 1.8 7.2 0.0 2.7 2 1 0 3 3 3 0 SNF2 family N-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EEQ38734.1 - 2.8e-09 37.7 0.2 4.7e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 EEQ38735.1 - 3.3e-18 65.3 0.1 5.7e-18 64.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ38735.1 - 0.04 13.5 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPP_enzyme_M_2 PF16582.5 EEQ38735.1 - 0.081 12.6 0.0 4.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Middle domain of thiamine pyrophosphate Maf PF02545.14 EEQ38736.1 - 6.2e-41 140.0 0.0 7.1e-41 139.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein His_Phos_1 PF00300.22 EEQ38737.1 - 1e-15 58.0 0.0 2.7e-15 56.6 0.0 1.8 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) 2-oxoacid_dh PF00198.23 EEQ38738.1 - 4.8e-74 248.7 0.4 5.9e-74 248.4 0.4 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EEQ38738.1 - 7.9e-17 60.9 0.1 1.4e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EEQ38738.1 - 1.4e-13 50.9 0.3 3.4e-13 49.7 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain Ribosomal_60s PF00428.19 EEQ38738.1 - 7.3 7.3 16.7 8.5 7.0 8.0 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein RNase_HII PF01351.18 EEQ38739.1 - 5.8e-54 183.0 0.0 7.2e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Mito_carr PF00153.27 EEQ38740.1 - 1.4e-57 191.6 3.3 7.6e-19 67.4 0.2 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.12 EEQ38741.1 - 9.3e-21 73.2 0.2 1.1e-20 72.9 0.2 1.1 1 0 0 1 1 1 1 TOM7 family Syja_N PF02383.18 EEQ38742.1 - 3.8e-73 246.6 4.9 6.8e-73 245.8 1.5 2.2 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.23 EEQ38742.1 - 5e-13 49.1 0.0 1.3e-12 47.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.16 EEQ38743.1 - 1.7e-30 104.8 0.9 3.5e-30 103.8 0.9 1.5 1 0 0 1 1 1 1 YEATS family Sec23_trunk PF04811.15 EEQ38745.1 - 1.1e-46 159.4 0.0 1.6e-45 155.6 0.0 2.1 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EEQ38745.1 - 1.2e-34 118.9 0.0 3.9e-34 117.3 0.0 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EEQ38745.1 - 7.3e-22 77.1 0.2 1.4e-21 76.3 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EEQ38745.1 - 2.5e-11 43.3 0.0 5.8e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 EEQ38745.1 - 2.9e-10 40.0 2.5 6.7e-10 38.9 2.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger tRNA-synt_2 PF00152.20 EEQ38746.1 - 6.1e-66 222.6 0.0 7.7e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ38746.1 - 5.5e-09 35.9 0.1 1.1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEQ38746.1 - 0.00064 19.3 0.1 0.12 11.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 EEQ38746.1 - 0.0081 16.3 0.0 0.037 14.2 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain UbiA PF01040.18 EEQ38747.1 - 4e-52 177.0 10.7 6e-52 176.4 10.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.8 EEQ38747.1 - 0.19 12.0 1.8 2.1 8.7 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) MitMem_reg PF13012.6 EEQ38748.1 - 4.3e-32 110.8 0.4 8.3e-32 109.9 0.4 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EEQ38748.1 - 1.8e-31 108.6 0.0 3.8e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2999 PF11212.8 EEQ38748.1 - 0.059 13.7 0.0 0.26 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) ATP_bind_1 PF03029.17 EEQ38749.1 - 8.8e-76 254.9 0.0 1.1e-75 254.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 EEQ38749.1 - 0.00085 19.3 0.0 0.25 11.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 EEQ38749.1 - 0.0051 15.8 0.0 0.0092 15.0 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 EEQ38749.1 - 0.01 15.4 0.0 0.03 13.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.7 EEQ38749.1 - 0.011 14.6 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MipZ PF09140.11 EEQ38749.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ AAA_33 PF13671.6 EEQ38749.1 - 0.033 14.4 0.0 0.059 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 EEQ38749.1 - 0.079 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.6 EEQ38749.1 - 0.085 13.3 0.5 0.7 10.3 0.1 2.5 3 0 0 3 3 3 0 AAA domain CLP1_P PF16575.5 EEQ38749.1 - 0.09 12.6 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_18 PF13238.6 EEQ38749.1 - 0.22 12.1 2.6 0.71 10.4 0.4 2.6 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 EEQ38749.1 - 0.23 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein TBCA PF02970.16 EEQ38750.1 - 1.6e-25 89.2 13.8 1.9e-25 89.0 13.8 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A EcKinase PF02958.20 EEQ38750.1 - 0.0074 15.6 1.8 0.0082 15.5 1.8 1.0 1 0 0 1 1 1 1 Ecdysteroid kinase Peptidase_S49_N PF08496.10 EEQ38750.1 - 0.016 15.3 5.5 0.019 15.0 5.5 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LRRC37AB_C PF14914.6 EEQ38750.1 - 0.035 14.0 2.0 0.041 13.8 2.0 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain FapA PF03961.13 EEQ38750.1 - 0.38 9.3 6.4 0.43 9.1 6.4 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DASH_Spc34 PF08657.10 EEQ38750.1 - 0.87 9.3 9.2 21 4.8 9.2 2.0 1 1 0 1 1 1 0 DASH complex subunit Spc34 TMPIT PF07851.13 EEQ38750.1 - 0.97 8.6 4.0 1 8.5 4.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4355 PF14265.6 EEQ38750.1 - 1.6 9.0 14.0 2.8 8.2 13.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4355) U1snRNP70_N PF12220.8 EEQ38750.1 - 3.5 8.3 7.9 8.7 7.1 7.9 1.7 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Prefoldin PF02996.17 EEQ38751.1 - 7e-09 35.6 0.9 7e-09 35.6 0.9 5.6 6 2 0 6 6 6 1 Prefoldin subunit DUF3835 PF12927.7 EEQ38751.1 - 0.00027 21.7 0.1 0.00027 21.7 0.1 6.8 5 1 0 5 5 5 1 Domain of unknown function (DUF3835) AcetylCoA_hydro PF02550.15 EEQ38752.1 - 7.9e-67 225.1 0.0 1.2e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EEQ38752.1 - 3.2e-42 144.1 0.0 4.7e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DnaJ_C PF01556.18 EEQ38753.1 - 2.6e-30 105.4 0.3 4.3e-30 104.8 0.3 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ38753.1 - 1.4e-22 79.5 6.9 2.6e-22 78.7 6.9 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEQ38753.1 - 1.1e-12 48.1 21.2 2.1e-12 47.2 21.2 1.5 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.6 EEQ38753.1 - 0.0068 16.9 13.3 0.086 13.3 2.7 2.6 2 0 0 2 2 2 2 Cytochrome c3 DUF5351 PF17302.2 EEQ38753.1 - 0.38 11.0 22.5 3.5 7.9 0.7 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5351) DUF2318 PF10080.9 EEQ38753.1 - 0.87 9.7 9.6 1.4 9.1 7.4 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) Cytochrom_CIII PF02085.16 EEQ38753.1 - 1.4 9.3 15.4 0.72 10.2 4.8 2.5 1 1 1 2 2 2 0 Class III cytochrome C family zf-TFIIB PF13453.6 EEQ38753.1 - 2.3 7.6 9.7 14 5.1 2.1 3.5 3 0 0 3 3 3 0 Transcription factor zinc-finger HypA PF01155.19 EEQ38753.1 - 8.1 6.5 11.8 6.1 6.9 1.8 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EEQ38753.1 - 9.4 5.8 10.6 4.6 6.9 1.4 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 RabGAP-TBC PF00566.18 EEQ38754.1 - 5.6e-16 58.9 5.2 5.6e-16 58.9 5.2 2.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain LZ_Tnp_IS66 PF13007.7 EEQ38754.1 - 0.14 12.9 0.1 0.47 11.3 0.0 1.9 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain Ran_BP1 PF00638.18 EEQ38755.1 - 4.4e-21 75.4 0.0 8.5e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 EEQ38755.1 - 3e-12 47.0 3.8 3e-12 47.0 3.8 5.2 5 1 0 5 5 5 1 NUP50 (Nucleoporin 50 kDa) RED_C PF07807.11 EEQ38755.1 - 2.3 8.7 7.5 3.5 8.1 1.1 4.4 4 2 1 5 5 5 0 RED-like protein C-terminal region Ribosomal_S25 PF03297.15 EEQ38756.1 - 5.8e-39 132.4 4.6 6.5e-39 132.2 4.6 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 EEQ38756.1 - 0.0024 17.6 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.16 EEQ38756.1 - 0.026 13.8 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family DUF365 PF04033.12 EEQ38756.1 - 0.039 14.2 0.2 0.058 13.7 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) HTH_CodY PF08222.11 EEQ38756.1 - 0.046 13.3 0.1 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain Polyketide_cyc PF03364.20 EEQ38757.1 - 1.7e-17 63.8 0.1 2.1e-17 63.6 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EEQ38757.1 - 0.0012 19.1 0.0 0.0014 18.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Melibiase_2 PF16499.5 EEQ38757.1 - 0.03 13.5 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Alpha galactosidase A PH_9 PF15410.6 EEQ38758.1 - 8.6e-08 32.6 0.1 6.2e-07 29.8 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EEQ38758.1 - 0.00046 20.7 1.6 0.019 15.4 0.0 3.0 2 1 1 3 3 3 1 PH domain F-box-like PF12937.7 EEQ38759.1 - 0.0013 18.6 0.2 0.0029 17.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ38759.1 - 0.0019 18.0 0.1 0.0062 16.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain Glyco_hydro_20 PF00728.22 EEQ38760.1 - 3.1e-99 332.7 1.8 4.7e-99 332.1 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EEQ38760.1 - 1.9e-16 60.9 0.0 4.5e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EEQ38760.1 - 0.0098 16.7 0.0 0.02 15.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 FAM35_C PF15793.5 EEQ38761.1 - 0.22 10.9 0.1 0.22 10.9 0.1 2.6 3 0 0 3 3 3 0 Protein family FAM35, C-terminal Glyco_hydro_76 PF03663.14 EEQ38762.1 - 2.8e-152 507.5 23.8 3.2e-152 507.3 23.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PX PF00787.24 EEQ38763.1 - 4.4e-16 58.9 2.4 7.6e-16 58.1 0.6 2.3 2 1 0 2 2 2 1 PX domain PGAP1 PF07819.13 EEQ38763.1 - 0.069 12.8 0.3 0.12 12.1 0.3 1.5 1 1 0 1 1 1 0 PGAP1-like protein CHDCT2 PF08074.11 EEQ38763.1 - 0.47 10.6 3.9 0.25 11.5 0.2 2.2 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Nup54 PF13874.6 EEQ38763.1 - 0.86 9.7 6.7 0.32 11.1 1.4 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 SlyX PF04102.12 EEQ38763.1 - 1.1 9.9 5.8 17 6.1 0.4 3.0 2 0 0 2 2 2 0 SlyX Lung_7-TM_R PF06814.13 EEQ38764.1 - 1e-58 198.9 19.8 2.1e-58 197.9 19.8 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor Wzy_C PF04932.15 EEQ38764.1 - 0.0012 18.5 0.4 0.0012 18.5 0.4 2.9 1 1 1 2 2 2 1 O-Antigen ligase COX2_TM PF02790.15 EEQ38764.1 - 0.04 14.1 0.1 0.04 14.1 0.1 2.5 2 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain TMEM43 PF07787.12 EEQ38764.1 - 0.61 9.4 5.3 1.1 8.5 5.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 43 PCI PF01399.27 EEQ38765.1 - 5.6e-11 42.9 0.2 5.6e-11 42.9 0.2 2.6 2 1 0 2 2 2 1 PCI domain Rpn9_C PF18261.1 EEQ38765.1 - 5.3e-05 22.7 0.2 0.00015 21.2 0.0 2.0 2 0 0 2 2 2 1 Rpn9 C-terminal helix Nab2 PF11517.8 EEQ38765.1 - 0.089 13.1 0.3 0.21 11.9 0.3 1.7 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) PX PF00787.24 EEQ38766.1 - 1.1e-15 57.6 0.4 3.4e-15 56.0 0.4 1.9 1 0 0 1 1 1 1 PX domain MIEAP PF16026.5 EEQ38766.1 - 0.059 13.6 1.8 0.12 12.6 0.0 2.3 3 0 0 3 3 3 0 Mitochondria-eating protein Paralemmin PF03285.15 EEQ38766.1 - 1.5 8.3 4.9 0.31 10.6 1.4 1.6 2 0 0 2 2 2 0 Paralemmin PAF PF15715.5 EEQ38766.1 - 3 8.4 8.2 0.16 12.6 1.8 2.1 2 1 0 2 2 2 0 PCNA-associated factor histone like domain Fib_alpha PF08702.10 EEQ38766.1 - 5.8 7.1 20.2 0.2 11.9 5.8 3.4 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family LCM PF04072.14 EEQ38767.1 - 9.8e-26 90.9 0.0 1.4e-25 90.3 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF4131 PF13567.6 EEQ38768.1 - 0.029 14.0 0.3 0.045 13.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 EEQ38768.1 - 0.083 12.9 0.5 0.16 12.0 0.5 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Methyltransf_11 PF08241.12 EEQ38769.1 - 6.5e-12 45.9 0.0 1e-11 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ38769.1 - 1.8e-10 41.3 0.0 3e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ38769.1 - 6.7e-08 32.5 0.0 2.1e-07 30.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ38769.1 - 3.4e-06 27.7 1.4 3.7e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ38769.1 - 2.4e-05 24.2 0.1 5e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EEQ38769.1 - 0.049 12.5 0.1 0.15 10.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 EEQ38769.1 - 0.07 12.5 0.0 0.14 11.4 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FAM176 PF14851.6 EEQ38769.1 - 0.12 12.1 1.3 0.18 11.4 1.3 1.2 1 0 0 1 1 1 0 FAM176 family PIG-S PF10510.9 EEQ38770.1 - 0.00038 19.4 0.2 0.0005 19.0 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.14 EEQ38772.1 - 8.7e-29 99.5 0.1 3.2e-28 97.6 0.1 1.9 1 1 0 1 1 1 1 hTAFII28-like protein conserved region DUF3419 PF11899.8 EEQ38774.1 - 2e-151 504.6 0.0 3e-151 504.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EEQ38774.1 - 8.4e-10 38.7 0.0 7.6e-09 35.6 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ38774.1 - 2.3e-08 34.6 0.0 3.2e-07 30.9 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ38774.1 - 2.7e-08 34.4 0.0 1.2e-06 29.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ38774.1 - 2.1e-06 28.3 0.0 6.3e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ38774.1 - 1.1e-05 24.9 0.0 3e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 EEQ38774.1 - 0.0041 16.8 0.0 0.05 13.2 0.0 2.4 2 1 0 3 3 3 1 Putative S-adenosyl-L-methionine-dependent methyltransferase CM_2 PF01817.21 EEQ38775.1 - 6.2e-05 23.3 0.0 0.48 10.8 0.1 2.7 2 1 0 2 2 2 2 Chorismate mutase type II DnaJ PF00226.31 EEQ38776.1 - 9.2e-09 35.3 1.9 4.3e-08 33.2 1.9 2.2 1 1 0 1 1 1 1 DnaJ domain CdiA_C PF18451.1 EEQ38777.1 - 0.03 14.5 0.7 0.064 13.5 0.7 1.6 1 0 0 1 1 1 0 Contact-dependent growth inhibition CdiA C-terminal domain STAT_bind PF02864.15 EEQ38777.1 - 3.5 8.2 12.4 0.28 11.7 4.0 2.5 2 1 1 3 3 3 0 STAT protein, DNA binding domain Amidohydro_1 PF01979.20 EEQ38778.1 - 3.6e-14 52.9 1.8 2.3e-13 50.2 1.8 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ38778.1 - 4.1e-09 36.4 4.9 1.9e-07 30.9 0.1 3.3 4 0 0 4 4 4 2 Amidohydrolase family Arteri_Gl PF00951.18 EEQ38778.1 - 0.043 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein GLEYA PF10528.9 EEQ38780.1 - 2.8e-12 46.9 0.3 1.5e-11 44.6 0.3 2.5 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 EEQ38780.1 - 5.9e-07 29.4 0.0 1.9e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 PA14 domain Trypan_PARP PF05887.11 EEQ38781.1 - 0.0019 18.1 6.5 0.0019 18.1 6.5 3.2 1 1 2 3 3 3 1 Procyclic acidic repetitive protein (PARP) DUF1997 PF09366.10 EEQ38781.1 - 0.19 11.9 0.5 0.73 10.0 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1997) PulA_N1 PF17999.1 EEQ38781.1 - 0.3 11.9 2.1 4 8.3 0.1 3.1 1 1 2 3 3 3 0 Pullulanase N1-terminal domain GLEYA PF10528.9 EEQ38782.1 - 5.4e-13 49.2 1.0 1.8e-12 47.5 1.0 2.0 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 EEQ38782.1 - 1.2e-06 28.4 0.1 2.7e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 PA14 domain DUF4251 PF14059.6 EEQ38782.1 - 0.12 12.4 0.1 2.5e+02 1.6 0.0 5.0 4 2 3 7 7 7 0 Domain of unknown function (DUF4251) TraG-D_C PF12696.7 EEQ38783.1 - 1 9.4 3.7 1 9.4 0.6 2.6 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG Hexokinase_2 PF03727.16 EEQ38785.1 - 4.4e-42 144.2 0.0 5.9e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EEQ38785.1 - 5.2e-30 104.8 0.0 4.7e-29 101.7 0.0 2.0 1 1 0 1 1 1 1 Hexokinase RHD3 PF05879.12 EEQ38786.1 - 1.4e-258 860.0 14.3 1.7e-258 859.7 14.3 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EEQ38786.1 - 7.7e-08 31.9 0.0 1.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_28 PF13521.6 EEQ38786.1 - 0.00049 20.4 0.8 0.0012 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EEQ38786.1 - 0.00059 19.9 0.0 0.00059 19.9 0.0 2.9 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EEQ38786.1 - 0.00062 19.8 0.0 0.002 18.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ38786.1 - 0.017 15.5 0.5 0.14 12.5 0.0 2.7 3 1 0 3 3 3 0 AAA ATPase domain FAM176 PF14851.6 EEQ38786.1 - 0.5 10.0 6.0 1.3 8.7 5.6 1.9 2 0 0 2 2 2 0 FAM176 family GTP_EFTU PF00009.27 EEQ38787.1 - 1.2e-61 207.6 0.0 1.8e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EEQ38787.1 - 3.9e-24 84.5 0.0 7.7e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EEQ38787.1 - 8.4e-17 61.0 0.1 2.9e-09 36.8 0.0 2.6 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ38787.1 - 1.3e-13 51.1 0.1 3.2e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EEQ38787.1 - 0.002 18.0 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EEQ38787.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AIG1 PF04548.16 EEQ38787.1 - 0.031 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family IMUP PF15761.5 EEQ38787.1 - 1.9 9.2 4.7 4.1 8.1 4.7 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 EEQ38787.1 - 5.1 6.6 7.1 9 5.8 7.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Peptidase_M48 PF01435.18 EEQ38788.1 - 5e-34 117.8 0.0 6e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 EEQ38788.1 - 0.007 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 SprT-like family UAA PF08449.11 EEQ38790.1 - 2.3e-72 243.8 8.8 2.7e-72 243.5 8.8 1.0 1 0 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EEQ38790.1 - 1e-07 31.5 12.0 1.4e-07 31.0 12.0 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 EEQ38790.1 - 0.0078 15.2 2.8 0.19 10.6 0.1 2.1 2 0 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like TadE PF07811.12 EEQ38790.1 - 0.018 15.3 0.8 2.5 8.4 0.0 2.9 2 0 0 2 2 2 0 TadE-like protein EamA PF00892.20 EEQ38790.1 - 0.081 13.1 16.0 1.7 8.8 0.6 2.9 2 1 0 2 2 2 0 EamA-like transporter family YitT_membrane PF02588.15 EEQ38790.1 - 0.2 11.0 5.8 0.058 12.8 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 MFS_1 PF07690.16 EEQ38791.1 - 1e-21 77.3 26.5 1e-21 77.3 26.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ38791.1 - 1.4e-06 27.9 1.7 1.4e-06 27.9 1.7 2.1 2 2 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Pox_A9 PF04835.12 EEQ38791.1 - 0.52 10.5 5.3 6.8 6.9 0.2 3.2 3 0 0 3 3 3 0 A9 protein conserved region ABC_membrane PF00664.23 EEQ38792.1 - 8.7e-52 176.5 45.6 2.4e-29 102.9 24.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ38792.1 - 6.7e-45 153.0 5.0 9.7e-28 97.4 0.0 3.5 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EEQ38792.1 - 5.3e-09 35.8 8.7 0.00019 20.9 1.0 4.4 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ38792.1 - 1.5e-06 27.8 0.4 0.031 14.0 0.3 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ38792.1 - 0.00014 21.8 2.9 0.077 12.9 1.6 2.7 2 0 0 2 2 2 2 RsgA GTPase Zeta_toxin PF06414.12 EEQ38792.1 - 0.00051 19.4 0.0 0.21 10.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 EEQ38792.1 - 0.0036 17.8 5.7 0.74 10.4 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.6 EEQ38792.1 - 0.0049 17.4 14.7 0.25 11.8 0.0 4.3 4 0 0 4 4 4 2 AAA domain IstB_IS21 PF01695.17 EEQ38792.1 - 0.0095 15.7 0.3 4.7 6.9 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_16 PF13191.6 EEQ38792.1 - 0.014 15.8 0.4 0.32 11.4 0.0 2.9 3 1 0 3 3 2 0 AAA ATPase domain AAA_21 PF13304.6 EEQ38792.1 - 0.019 14.8 18.2 0.31 10.8 0.1 5.2 4 2 1 6 6 5 0 AAA domain, putative AbiEii toxin, Type IV TA system Vps51 PF08700.11 EEQ38792.1 - 0.05 13.7 1.9 0.096 12.8 0.1 2.4 2 0 0 2 2 2 0 Vps51/Vps67 RPA43_OB PF17875.1 EEQ38792.1 - 0.059 14.0 1.0 0.15 12.7 1.0 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I AAA_30 PF13604.6 EEQ38792.1 - 0.11 12.2 0.7 11 5.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EEQ38792.1 - 0.12 12.3 1.3 12 5.8 0.1 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 EEQ38792.1 - 0.21 11.3 1.5 3.6 7.3 0.1 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 EEQ38792.1 - 0.21 11.9 3.7 20 5.5 0.2 3.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EEQ38792.1 - 0.25 11.4 8.7 0.48 10.5 0.2 3.5 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_25 PF13481.6 EEQ38792.1 - 0.44 10.1 1.2 3.1 7.3 0.1 2.5 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 EEQ38792.1 - 1.3 7.9 5.7 2.8 6.8 0.2 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PTR2 PF00854.21 EEQ38793.1 - 3.1e-94 316.0 14.2 5.2e-94 315.3 12.1 2.1 1 1 0 1 1 1 1 POT family DUF2244 PF10003.9 EEQ38793.1 - 1.6 8.4 0.0 1.6 8.4 0.0 2.6 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) P_C PF06640.11 EEQ38795.1 - 0.035 14.2 0.1 0.054 13.6 0.1 1.2 1 0 0 1 1 1 0 P protein C-terminus AdoMet_dc PF02675.15 EEQ38795.1 - 0.041 14.1 0.0 0.089 13.1 0.0 1.8 1 1 0 1 1 1 0 S-adenosylmethionine decarboxylase MR_MLE_C PF13378.6 EEQ38796.1 - 1e-43 149.5 0.0 1.7e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EEQ38796.1 - 4.9e-07 30.0 0.0 8.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF917 PF06032.12 EEQ38797.1 - 0.088 11.6 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF917) CysG_dimeriser PF10414.9 EEQ38797.1 - 2.2 8.1 4.4 6.3 6.6 0.2 3.1 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region Bac_rhamnosid6H PF17389.2 EEQ38799.1 - 5.3e-105 351.4 0.2 8.4e-105 350.8 0.2 1.3 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EEQ38799.1 - 4.1e-48 163.4 0.1 4.1e-48 163.4 0.1 1.7 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EEQ38799.1 - 2.9e-27 94.6 0.0 5.2e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 EEQ38799.1 - 3.4e-22 78.0 0.0 8.3e-22 76.8 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain adh_short_C2 PF13561.6 EEQ38800.1 - 4.6e-62 209.6 0.6 6.4e-62 209.2 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ38800.1 - 2.3e-46 157.7 1.6 2.9e-46 157.4 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ38800.1 - 3.2e-12 46.7 0.7 4.8e-12 46.2 0.7 1.2 1 0 0 1 1 1 1 KR domain Sybindin PF04099.12 EEQ38800.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Sybindin-like family PALP PF00291.25 EEQ38800.1 - 0.029 13.8 1.5 0.069 12.5 0.2 2.0 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Amidohydro_2 PF04909.14 EEQ38801.1 - 4.7e-15 56.1 1.7 7.1e-15 55.6 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase Methyltransf_9 PF08003.11 EEQ38801.1 - 0.0097 14.9 0.2 0.017 14.1 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DHDPS PF00701.22 EEQ38802.1 - 9.5e-36 123.0 0.0 1.2e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Peripla_BP_1 PF00532.21 EEQ38802.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Sugar_tr PF00083.24 EEQ38803.1 - 9.1e-65 219.3 24.5 1.2e-64 218.8 24.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ38803.1 - 2.7e-22 79.2 25.2 1.2e-21 77.1 20.8 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ38803.1 - 0.00081 18.4 11.6 0.0058 15.5 3.4 2.4 2 0 0 2 2 2 2 MFS_1 like family DUF5432 PF17497.2 EEQ38803.1 - 0.91 9.7 3.7 1.4 9.1 2.4 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5432) Fungal_trans PF04082.18 EEQ38804.1 - 1.6e-11 43.8 1.9 2.4e-11 43.2 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ38804.1 - 2.6e-06 27.4 14.3 5.7e-06 26.4 14.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XhlA PF10779.9 EEQ38804.1 - 0.096 12.9 0.4 0.28 11.4 0.4 1.7 1 0 0 1 1 1 0 Haemolysin XhlA MAGI_u5 PF16666.5 EEQ38804.1 - 0.65 10.2 3.0 1.4 9.1 3.0 1.4 1 0 0 1 1 1 0 Unstructured region on MAGI Pkinase PF00069.25 EEQ38806.1 - 4.8e-75 252.3 0.0 8.3e-75 251.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38806.1 - 2.5e-36 125.3 0.0 3.8e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EEQ38806.1 - 7.2e-28 96.8 2.1 4.1e-13 49.5 0.0 3.2 3 0 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 EEQ38806.1 - 2.3e-10 40.6 0.0 5.6e-06 26.6 0.0 2.7 2 1 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Kinase-like PF14531.6 EEQ38806.1 - 8.3e-10 38.4 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ38806.1 - 0.00029 20.3 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA_2 PF17913.1 EEQ38806.1 - 0.00099 19.3 0.0 0.086 13.1 0.0 3.4 3 1 0 3 3 3 1 FHA domain APH PF01636.23 EEQ38806.1 - 0.0013 18.7 0.1 0.051 13.5 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EEQ38806.1 - 0.077 12.6 0.6 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Kinesin PF00225.23 EEQ38807.1 - 7.9e-90 301.2 0.4 1.6e-89 300.2 0.4 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ38807.1 - 9.6e-25 87.3 0.3 5.3e-24 84.8 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 EEQ38807.1 - 0.048 13.8 0.3 1 9.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain APG6_N PF17675.1 EEQ38807.1 - 0.05 14.1 15.7 0.03 14.8 3.8 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Med9 PF07544.13 EEQ38807.1 - 3.2 7.9 10.1 16 5.6 3.3 3.5 2 2 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 COMP PF11598.8 EEQ38807.1 - 4.9 7.7 10.9 2.7 8.6 2.1 2.9 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein DUF4523 PF15023.6 EEQ38808.1 - 0.0059 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) RRM_1 PF00076.22 EEQ38808.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TruD PF01142.18 EEQ38809.1 - 3.3e-73 246.9 3.3 2.5e-69 234.1 0.0 3.8 2 1 1 3 3 3 2 tRNA pseudouridine synthase D (TruD) Rhodanese PF00581.20 EEQ38811.1 - 5.4e-15 55.8 0.0 4.1e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain WD40 PF00400.32 EEQ38812.1 - 7.7e-19 67.7 19.3 5.6e-06 27.0 0.3 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 EEQ38812.1 - 0.00033 19.5 1.8 0.00082 18.1 0.2 2.2 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EEQ38812.1 - 0.012 14.4 0.0 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 Nup133 N terminal like Ist1 PF03398.14 EEQ38813.1 - 2.9e-58 196.4 0.4 4.2e-58 195.9 0.4 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ATP-synt_D PF01813.17 EEQ38813.1 - 0.36 10.6 4.7 0.6 9.9 4.7 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Pkinase PF00069.25 EEQ38814.1 - 3.7e-50 170.7 0.3 5.2e-45 153.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38814.1 - 2.7e-17 62.9 1.0 6.3e-17 61.7 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase DUF812 PF05667.11 EEQ38814.1 - 0.00022 20.3 17.9 0.00022 20.3 17.9 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF812) APH PF01636.23 EEQ38814.1 - 0.018 15.0 0.4 0.16 11.9 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Mem_trans PF03547.18 EEQ38815.1 - 0.27 9.6 0.2 0.24 9.8 0.2 1.0 1 0 0 1 1 1 0 Membrane transport protein Sof1 PF04158.14 EEQ38816.1 - 2.5e-31 107.8 14.2 4e-31 107.1 14.2 1.3 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EEQ38816.1 - 9.1e-31 105.4 11.1 7.6e-07 29.7 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38816.1 - 4.9e-07 29.9 0.0 0.0012 19.2 0.0 3.0 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ38816.1 - 0.00031 20.7 0.4 0.0011 18.9 0.3 1.9 1 1 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.6 EEQ38816.1 - 0.019 15.0 0.0 5.9 7.0 0.0 3.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Lbh PF15317.6 EEQ38816.1 - 0.11 13.3 0.2 0.24 12.3 0.2 1.5 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein NIF PF03031.18 EEQ38817.1 - 9.6e-52 174.9 0.2 1.3e-51 174.4 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Strabismus PF06638.11 EEQ38817.1 - 2.3 6.8 5.2 3.1 6.3 5.2 1.1 1 0 0 1 1 1 0 Strabismus protein CLP1_P PF16575.5 EEQ38819.1 - 7.9e-34 117.1 0.0 1.3e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EEQ38819.1 - 1.6e-29 102.6 0.1 2.8e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EEQ38819.1 - 3.4e-23 81.7 0.0 1.7e-22 79.4 0.0 2.0 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 EEQ38819.1 - 0.0029 17.5 0.0 0.0064 16.3 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EEQ38819.1 - 0.054 13.9 0.0 0.09 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3667 PF12412.8 EEQ38819.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) AAA_19 PF13245.6 EEQ38819.1 - 0.14 12.4 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain PTPA PF03095.15 EEQ38821.1 - 1e-111 373.2 0.0 1.2e-111 373.0 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein LETM1 PF07766.13 EEQ38822.1 - 0.0062 15.9 6.5 0.036 13.4 0.0 2.9 3 0 0 3 3 3 2 LETM1-like protein AIF-MLS PF14962.6 EEQ38822.1 - 0.19 11.6 14.7 0.39 10.6 14.7 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence BORG_CEP PF14957.6 EEQ38822.1 - 0.34 12.1 1.8 0.59 11.3 1.8 1.3 1 0 0 1 1 1 0 Cdc42 effector DUF966 PF06136.13 EEQ38822.1 - 0.9 9.2 5.5 1.2 8.7 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dicty_REP PF05086.12 EEQ38822.1 - 2.4 6.0 3.5 3 5.7 3.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MOZ_SAS PF01853.18 EEQ38823.1 - 7.3e-81 270.1 0.1 1.2e-80 269.4 0.1 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EEQ38823.1 - 1.6e-22 78.8 0.2 4.2e-22 77.5 0.2 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 EEQ38823.1 - 6.4e-21 74.0 1.4 1.4e-20 72.9 1.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HNF-1_N PF04814.13 EEQ38823.1 - 0.075 13.7 3.8 0.16 12.5 3.8 1.5 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Acetyltransf_7 PF13508.7 EEQ38823.1 - 0.093 13.2 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Syntaphilin PF15290.6 EEQ38823.1 - 0.23 11.1 5.9 0.37 10.4 5.9 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Sec10 PF07393.11 EEQ38823.1 - 0.4 9.0 3.1 0.57 8.5 3.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 WD40 PF00400.32 EEQ38824.1 - 1.4e-38 130.2 7.7 1.5e-06 28.8 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38824.1 - 6.5e-07 29.6 0.0 1.1 9.7 0.0 5.0 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ38824.1 - 0.0011 17.7 0.2 1.1 7.8 0.0 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 CbiG_N PF11760.8 EEQ38824.1 - 0.041 13.9 1.7 0.16 12.0 0.1 2.6 2 0 0 2 2 2 0 Cobalamin synthesis G N-terminal Frtz PF11768.8 EEQ38824.1 - 0.24 9.6 0.0 5.2 5.2 0.1 2.4 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz TPR_14 PF13428.6 EEQ38825.1 - 0.1 13.5 1.0 0.98 10.4 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Atrophin-1 PF03154.15 EEQ38825.1 - 1.5 7.0 8.6 2.5 6.3 8.6 1.3 1 0 0 1 1 1 0 Atrophin-1 family PI31_Prot_C PF08577.11 EEQ38827.1 - 1.3e-13 52.0 10.8 1.3e-13 52.0 10.8 2.8 2 2 1 3 3 3 1 PI31 proteasome regulator Keratin_2_head PF16208.5 EEQ38827.1 - 4.7 7.3 24.4 6.6 6.9 24.4 1.3 1 0 0 1 1 1 0 Keratin type II head Glucosamine_iso PF01182.20 EEQ38828.1 - 5.3e-53 180.2 0.0 8.3e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ABC_membrane PF00664.23 EEQ38829.1 - 9.6e-55 186.1 38.3 4e-37 128.3 14.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ38829.1 - 2.8e-48 163.9 0.0 6.2e-33 114.2 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ38829.1 - 7.5e-14 51.7 0.1 0.0031 17.0 0.0 4.2 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ38829.1 - 6.9e-07 29.4 0.0 0.82 9.4 0.0 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ38829.1 - 7.1e-07 28.9 0.8 0.0018 18.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ38829.1 - 1.6e-05 25.4 0.1 0.0023 18.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 EEQ38829.1 - 3.2e-05 24.5 0.4 0.36 11.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EEQ38829.1 - 8.3e-05 23.1 1.0 0.075 13.6 0.1 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EEQ38829.1 - 0.0002 21.4 0.1 0.083 13.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EEQ38829.1 - 0.00048 19.9 1.8 0.049 13.3 0.2 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EEQ38829.1 - 0.00051 20.3 2.4 0.78 10.0 0.2 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EEQ38829.1 - 0.00089 19.2 0.3 0.66 9.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase T2SSE PF00437.20 EEQ38829.1 - 0.0016 17.6 0.2 0.007 15.4 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_28 PF13521.6 EEQ38829.1 - 0.003 17.8 1.1 0.022 15.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EEQ38829.1 - 0.0031 17.1 2.0 0.032 13.8 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 EEQ38829.1 - 0.0075 16.2 1.1 0.33 10.8 0.2 2.5 2 0 0 2 2 2 1 NTPase ATP_bind_1 PF03029.17 EEQ38829.1 - 0.0076 16.0 1.3 2.6 7.8 0.3 3.1 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein NACHT PF05729.12 EEQ38829.1 - 0.0099 15.8 1.2 0.12 12.3 0.1 2.6 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 EEQ38829.1 - 0.017 15.2 0.3 7.7 6.5 0.1 2.7 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 EEQ38829.1 - 0.029 14.8 0.0 24 5.4 0.0 3.3 3 0 0 3 3 3 0 RNA helicase dNK PF01712.19 EEQ38829.1 - 0.031 14.1 0.4 0.31 10.9 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase TsaE PF02367.17 EEQ38829.1 - 0.032 14.2 1.3 0.31 11.0 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EEQ38829.1 - 0.044 13.4 5.0 0.35 10.4 0.4 3.7 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.12 EEQ38829.1 - 0.059 12.6 1.2 4.3 6.6 0.2 2.8 2 0 0 2 2 2 0 Zeta toxin ATPase_2 PF01637.18 EEQ38829.1 - 0.078 12.9 0.0 1.3 8.9 0.0 2.7 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ABC_ATPase PF09818.9 EEQ38829.1 - 0.082 11.7 5.6 2 7.1 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Roc PF08477.13 EEQ38829.1 - 0.084 13.1 0.1 4.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EEQ38829.1 - 0.12 11.7 3.2 1.1 8.5 0.2 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.29 EEQ38829.1 - 0.13 12.7 0.3 5.3 7.5 0.2 2.9 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EEQ38829.1 - 0.13 11.9 0.0 10 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 EEQ38829.1 - 0.2 10.8 0.7 18 4.4 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 EEQ38829.1 - 0.22 11.7 1.1 6.9 6.8 0.4 2.6 2 0 0 2 2 2 0 AAA domain DLIC PF05783.11 EEQ38829.1 - 0.42 9.4 1.9 0.36 9.6 0.0 1.8 3 0 0 3 3 3 0 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 EEQ38829.1 - 3.6 7.3 4.5 4.9 6.9 0.1 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation UCH PF00443.29 EEQ38830.1 - 5.3e-53 180.1 0.0 7.6e-53 179.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ38830.1 - 1.8e-18 67.3 1.0 6.4e-18 65.4 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EEQ38830.1 - 2.9e-07 30.7 7.8 2.9e-07 30.7 7.8 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Mu-like_Com PF10122.9 EEQ38830.1 - 0.2 11.2 2.2 0.73 9.3 2.2 2.0 1 0 0 1 1 1 0 Mu-like prophage protein Com Peptidase_C98 PF15499.6 EEQ38830.1 - 0.57 9.6 5.5 1.4 8.4 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Phosducin PF02114.16 EEQ38831.1 - 1.2e-13 50.6 3.8 1.2e-13 50.6 3.8 1.7 1 1 1 2 2 2 1 Phosducin Thioredoxin PF00085.20 EEQ38831.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin DUF572 PF04502.13 EEQ38831.1 - 2.3 7.8 10.0 0.19 11.3 2.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF866 PF05907.13 EEQ38832.1 - 3.2e-59 199.3 3.0 3.6e-59 199.1 3.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ribosomal_L44 PF00935.19 EEQ38832.1 - 0.014 15.9 3.4 1.2 9.6 0.5 2.3 2 0 0 2 2 2 0 Ribosomal protein L44 Elf1 PF05129.13 EEQ38832.1 - 0.034 14.2 1.9 0.11 12.6 1.9 1.8 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 EEQ38832.1 - 0.068 13.3 1.4 5.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Cytochrom_c3_2 PF14537.6 EEQ38832.1 - 0.2 12.1 3.0 3.8 8.0 0.1 2.3 1 1 1 2 2 2 0 Cytochrome c3 Cytochrom_C PF00034.21 EEQ38833.1 - 1.5e-11 45.3 0.0 2.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EEQ38833.1 - 9.6e-07 29.0 2.3 9.4e-06 25.9 2.3 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EEQ38833.1 - 0.11 12.2 0.6 0.47 10.2 0.2 1.9 2 0 0 2 2 2 0 Cytochrome c-550 domain MA3 PF02847.17 EEQ38834.1 - 5.3e-15 55.4 0.1 1.2e-14 54.2 0.1 1.6 1 0 0 1 1 1 1 MA3 domain CNOT1_TTP_bind PF16417.5 EEQ38834.1 - 0.48 9.6 4.1 0.74 9.0 2.7 2.0 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 TTP binding domain Mem_trans PF03547.18 EEQ38834.1 - 1.2 7.5 4.1 0.83 8.0 0.7 2.1 2 0 0 2 2 2 0 Membrane transport protein PPR_2 PF13041.6 EEQ38835.1 - 2.6e-06 27.5 0.0 0.041 14.1 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family CTP_transf_like PF01467.26 EEQ38836.1 - 4.1e-10 40.0 0.0 6.7e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EEQ38836.1 - 0.0052 16.7 0.1 0.0094 15.8 0.1 1.4 1 0 0 1 1 1 1 FAD synthetase USP7_C2 PF14533.6 EEQ38837.1 - 2.8e-56 190.5 7.5 5.9e-55 186.2 3.5 3.2 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EEQ38837.1 - 4.8e-45 154.1 1.1 8e-45 153.3 0.3 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 EEQ38837.1 - 4.7e-42 143.9 3.5 1.3e-40 139.2 0.5 3.4 3 1 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 EEQ38837.1 - 1.7e-19 70.6 0.2 4.3e-18 66.0 0.0 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EEQ38837.1 - 3.5e-07 30.4 0.0 1.3e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 MATH domain UN_NPL4 PF11543.8 EEQ38837.1 - 0.00064 20.2 0.2 5.9 7.4 0.0 3.8 4 0 0 4 4 4 1 Nuclear pore localisation protein NPL4 DUF5049 PF16468.5 EEQ38837.1 - 0.16 11.9 0.2 0.51 10.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5049) Glyco_hydro_17 PF00332.18 EEQ38840.1 - 8.3e-08 32.2 1.8 1.6e-07 31.2 1.2 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Macoilin PF09726.9 EEQ38840.1 - 0.93 8.0 2.4 1.2 7.6 2.4 1.1 1 0 0 1 1 1 0 Macoilin family Rap1-DNA-bind PF09197.10 EEQ38841.1 - 2.5e-34 118.1 6.0 7.8e-32 110.1 0.6 2.7 2 0 0 2 2 2 2 Rap1, DNA-binding Rap1_C PF11626.8 EEQ38841.1 - 1.6e-11 44.1 0.4 1.8e-10 40.7 0.0 2.9 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 EEQ38841.1 - 3.7e-09 36.9 0.0 8.4e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-bind_2 PF08914.11 EEQ38841.1 - 3.8e-06 27.0 3.3 0.015 15.5 0.1 2.9 2 0 0 2 2 2 2 Rap1 Myb domain Aldo_ket_red PF00248.21 EEQ38842.1 - 2.9e-47 161.3 0.0 3.4e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HHH_2 PF12826.7 EEQ38842.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Metallophos PF00149.28 EEQ38843.1 - 4.6e-11 43.6 0.5 9.2e-11 42.6 0.5 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EEQ38843.1 - 0.0022 18.2 0.0 0.0069 16.6 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain RabGAP-TBC PF00566.18 EEQ38844.1 - 3.3e-31 108.6 18.1 2.2e-29 102.7 7.8 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain rRNA_proc-arch PF13234.6 EEQ38845.1 - 2.7e-81 273.5 1.1 5.3e-81 272.5 0.1 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 EEQ38845.1 - 5e-57 192.1 0.5 1e-56 191.1 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EEQ38845.1 - 3.7e-19 69.2 0.1 4.3e-17 62.4 0.0 3.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ38845.1 - 4.9e-06 26.9 0.0 2.2e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ38845.1 - 0.00081 19.4 0.0 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EEQ38845.1 - 0.012 15.9 0.0 0.088 13.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 EEQ38845.1 - 0.041 12.9 0.6 0.39 9.7 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF1275 PF06912.11 EEQ38848.1 - 0.41 10.6 5.5 0.72 9.8 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Peptidase_S10 PF00450.22 EEQ38850.1 - 2.6e-133 445.5 1.4 3.2e-133 445.2 1.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EEQ38850.1 - 2.6e-24 86.1 0.1 4.3e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Pkinase PF00069.25 EEQ38851.1 - 1.2e-43 149.4 0.0 2.5e-43 148.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ38851.1 - 5.8e-25 88.0 0.0 7.7e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ38851.1 - 0.0019 18.2 1.2 0.0094 15.9 0.2 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ38851.1 - 0.022 14.1 0.4 0.041 13.2 0.4 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ38851.1 - 0.022 14.1 0.0 0.06 12.7 0.0 1.7 1 1 1 2 2 2 0 Kinase-like SHMT PF00464.19 EEQ38852.1 - 9.7e-206 683.0 0.0 1.2e-205 682.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase DegT_DnrJ_EryC1 PF01041.17 EEQ38852.1 - 0.028 13.8 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family VPS11_C PF12451.8 EEQ38852.1 - 0.099 12.9 0.1 17 5.7 0.1 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal Med16 PF11635.8 EEQ38854.1 - 2.7e-163 544.8 0.0 3.6e-163 544.4 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 DUF3533 PF12051.8 EEQ38855.1 - 9.2e-92 307.9 19.1 1.1e-91 307.6 19.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) TMEM252 PF15664.5 EEQ38855.1 - 0.068 12.9 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Transmembrane protein 252 family DUF3533 PF12051.8 EEQ38856.1 - 7.2e-105 351.0 12.6 8.5e-105 350.8 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) TMIE PF16038.5 EEQ38856.1 - 0.016 15.0 0.3 0.042 13.7 0.3 1.7 1 0 0 1 1 1 0 TMIE protein S1FA PF04689.13 EEQ38856.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.5 2 1 0 2 2 2 0 DNA binding protein S1FA PDR_CDR PF06422.12 EEQ38856.1 - 0.21 11.5 1.8 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 CDR ABC transporter HSM3_C PF18794.1 EEQ38857.1 - 5.7e-10 39.1 0.0 1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, C terminal domain Zemlya PF17646.1 EEQ38857.1 - 0.0052 17.1 0.1 0.027 14.8 0.1 2.2 2 0 0 2 2 2 1 Closterovirus 1a polyprotein central region Sec7 PF01369.20 EEQ38858.1 - 3.5e-23 82.2 0.1 2.3e-22 79.5 0.1 2.3 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.6 EEQ38858.1 - 0.00011 22.5 1.2 0.0014 18.9 0.0 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain DUF737 PF05300.11 EEQ38858.1 - 0.017 15.5 0.3 0.017 15.5 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF737) Proteasome PF00227.26 EEQ38859.1 - 2.1e-38 131.7 0.0 2.3e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Cmc1 PF08583.10 EEQ38860.1 - 2.5e-17 62.6 8.8 3.7e-17 62.1 8.8 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 EEQ38860.1 - 0.0073 16.0 2.1 0.011 15.4 2.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Takusan PF04822.13 EEQ38860.1 - 0.011 15.6 2.0 0.019 14.8 2.0 1.6 1 1 0 1 1 1 0 Takusan CHCH PF06747.13 EEQ38860.1 - 0.16 12.1 4.8 0.27 11.4 0.8 2.3 2 0 0 2 2 2 0 CHCH domain E1_dh PF00676.20 EEQ38861.1 - 1.4e-118 395.2 0.1 1.7e-118 395.0 0.1 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EEQ38861.1 - 0.041 13.1 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.6 EEQ38861.1 - 1.2 10.2 6.3 1.5 9.8 0.5 3.1 2 2 1 3 3 3 0 KRTAP type 7 family Sec63 PF02889.16 EEQ38863.1 - 7.4e-135 448.1 0.0 5.5e-71 238.7 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EEQ38863.1 - 3.8e-40 137.5 0.0 8.5e-24 84.3 0.0 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EEQ38863.1 - 7e-20 71.7 0.0 2.9e-10 40.4 0.0 2.9 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ38863.1 - 4.5e-12 46.3 0.0 5.9e-08 33.0 0.0 3.3 2 1 0 2 2 2 2 Helicase conserved C-terminal domain Helicase_PWI PF18149.1 EEQ38863.1 - 2.9e-08 33.9 0.5 1.7e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA_22 PF13401.6 EEQ38863.1 - 3.3e-06 27.4 0.0 0.058 13.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ38863.1 - 0.00011 22.6 2.3 0.013 15.9 0.4 3.3 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 EEQ38863.1 - 0.00017 21.1 0.0 0.011 15.3 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 EEQ38863.1 - 0.00033 20.3 5.3 0.15 11.6 0.1 3.1 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EEQ38863.1 - 0.0029 17.4 0.0 3.8 7.2 0.0 2.9 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EEQ38863.1 - 0.053 13.0 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 EEQ38863.1 - 0.48 10.2 3.1 16 5.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain CENP-B_dimeris PF09026.10 EEQ38863.1 - 2.4 8.6 13.5 0.32 11.4 2.5 3.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glycos_transf_3 PF00591.21 EEQ38864.1 - 1.3e-79 267.4 0.1 1.7e-79 267.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EEQ38864.1 - 1.1e-13 50.8 0.0 2.3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Dehalogenase PF13486.6 EEQ38864.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Cnn_1N PF07989.11 EEQ38865.1 - 1.2e-06 28.5 18.7 2.5e-06 27.6 5.0 14.1 5 3 8 13 13 13 4 Centrosomin N-terminal motif 1 Spc7 PF08317.11 EEQ38865.1 - 5.7e-05 22.1 13.6 5.7e-05 22.1 13.6 7.5 2 2 5 7 7 7 4 Spc7 kinetochore protein Cep57_CLD_2 PF14197.6 EEQ38865.1 - 0.00074 19.6 13.8 0.00074 19.6 13.8 15.1 9 3 5 15 15 15 1 Centrosome localisation domain of PPC89 KLRAQ PF10205.9 EEQ38865.1 - 0.0033 17.6 7.0 0.0033 17.6 7.0 11.1 1 1 9 12 12 12 1 Predicted coiled-coil domain-containing protein Rootletin PF15035.6 EEQ38865.1 - 0.008 16.2 18.4 0.008 16.2 18.4 9.2 1 1 6 7 7 7 1 Ciliary rootlet component, centrosome cohesion Ax_dynein_light PF10211.9 EEQ38865.1 - 0.009 16.0 4.6 0.009 16.0 4.6 12.1 1 1 12 13 13 13 1 Axonemal dynein light chain CENP-F_leu_zip PF10473.9 EEQ38865.1 - 0.011 15.7 6.9 0.011 15.7 6.9 10.4 2 2 9 11 11 11 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sod_Fe_N PF00081.22 EEQ38865.1 - 0.14 12.6 1.9 5.7 7.5 0.2 4.0 1 1 1 2 2 2 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Spc110_C PF18520.1 EEQ38865.1 - 0.43 10.2 7.2 0.068 12.8 0.9 3.2 3 0 0 3 3 3 0 Spindle pole body component 110 C-terminal domain Fez1 PF06818.15 EEQ38865.1 - 6.8 7.1 155.7 0.031 14.7 13.4 7.8 2 2 5 7 7 7 0 Fez1 Apc13p PF05839.11 EEQ38866.1 - 2.9e-07 30.6 0.1 8.3e-07 29.1 0.1 1.8 1 1 0 1 1 1 1 Apc13p protein RNA_pol_Rpb1_1 PF04997.12 EEQ38867.1 - 1.4e-82 277.5 0.0 2.2e-82 276.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EEQ38867.1 - 5.3e-81 272.0 0.2 9e-81 271.2 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EEQ38867.1 - 5.8e-75 251.1 0.0 1.5e-74 249.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EEQ38867.1 - 5.8e-39 133.5 0.1 2.2e-38 131.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EEQ38867.1 - 1.3e-30 105.5 0.0 4.8e-30 103.7 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF445 PF04286.12 EEQ38867.1 - 0.21 11.4 3.8 0.46 10.2 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF445) DSS1_SEM1 PF05160.13 EEQ38868.1 - 1.2e-20 73.3 17.5 1.4e-20 73.1 17.5 1.0 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 EEQ38869.1 - 7.4e-41 139.7 0.0 1.4e-40 138.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EEQ38869.1 - 1.6e-17 63.2 0.1 3.3e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EEQ38869.1 - 3e-08 33.3 0.0 8.8e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ38869.1 - 1e-05 26.0 0.3 0.022 15.1 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EEQ38869.1 - 8.2e-05 22.8 0.0 0.00026 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EEQ38869.1 - 0.0007 19.6 0.3 0.0065 16.5 0.2 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ38869.1 - 0.00072 19.3 0.1 0.0017 18.1 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ38869.1 - 0.0011 19.2 1.0 0.17 12.1 0.0 3.3 3 1 1 4 4 3 1 AAA domain AAA_33 PF13671.6 EEQ38869.1 - 0.0033 17.6 0.0 0.01 16.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EEQ38869.1 - 0.012 14.8 0.0 0.039 13.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.16 EEQ38869.1 - 0.016 14.6 0.1 0.063 12.7 0.1 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 EEQ38869.1 - 0.018 14.5 0.1 0.048 13.0 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EEQ38869.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 EEQ38869.1 - 0.1 12.3 0.2 0.4 10.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EEQ38869.1 - 0.16 11.7 0.5 0.57 9.9 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EEQ38869.1 - 0.33 10.7 3.1 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Cation_efflux PF01545.21 EEQ38870.1 - 3.2e-39 134.7 9.0 3.2e-39 134.7 9.0 2.9 2 1 1 3 3 3 1 Cation efflux family SPX PF03105.19 EEQ38870.1 - 0.13 12.2 0.9 0.19 11.6 0.9 1.2 1 0 0 1 1 1 0 SPX domain ATP_bind_1 PF03029.17 EEQ38871.1 - 2.1e-86 289.7 0.0 2.3e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EEQ38871.1 - 0.0002 20.4 0.0 0.00086 18.4 0.0 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 EEQ38871.1 - 0.00049 19.9 0.0 0.0019 18.0 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop RsgA_GTPase PF03193.16 EEQ38871.1 - 0.0014 18.5 0.3 0.033 14.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_31 PF13614.6 EEQ38871.1 - 0.0023 17.9 0.0 0.12 12.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ38871.1 - 0.0027 18.3 0.0 0.0076 16.8 0.0 1.8 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EEQ38871.1 - 0.0029 17.4 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EEQ38871.1 - 0.0034 17.7 0.0 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 EEQ38871.1 - 0.0037 17.3 0.0 0.011 15.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Fer4_NifH PF00142.18 EEQ38871.1 - 0.0044 16.5 0.0 0.011 15.2 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF87 PF01935.17 EEQ38871.1 - 0.008 16.3 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 EEQ38871.1 - 0.012 16.0 0.2 0.042 14.2 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 EEQ38871.1 - 0.013 14.5 0.0 0.03 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_19 PF13245.6 EEQ38871.1 - 0.014 15.8 0.0 0.036 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 EEQ38871.1 - 0.015 15.3 0.0 0.02 14.9 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_5 PF07728.14 EEQ38871.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 EEQ38871.1 - 0.017 15.6 0.0 0.04 14.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EEQ38871.1 - 0.021 14.1 0.0 0.042 13.1 0.0 1.5 2 0 0 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 EEQ38871.1 - 0.022 14.3 0.0 0.056 13.0 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region GTP_EFTU PF00009.27 EEQ38871.1 - 0.029 13.9 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EEQ38871.1 - 0.035 14.4 0.0 0.078 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ38871.1 - 0.046 14.2 0.0 0.11 13.0 0.0 1.6 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EEQ38871.1 - 0.056 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArsA_ATPase PF02374.15 EEQ38871.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_30 PF13604.6 EEQ38871.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EEQ38871.1 - 0.063 12.5 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SSE PF00437.20 EEQ38871.1 - 0.067 12.2 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 EEQ38871.1 - 0.07 13.0 0.0 0.17 11.8 0.0 1.6 2 0 0 2 2 1 0 NACHT domain NTPase_1 PF03266.15 EEQ38871.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NTPase AIG1 PF04548.16 EEQ38871.1 - 0.088 12.1 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Sigma54_activat PF00158.26 EEQ38871.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain Septin PF00735.18 EEQ38871.1 - 0.094 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_14 PF13173.6 EEQ38871.1 - 0.099 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EEQ38871.1 - 0.19 12.1 0.0 0.86 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EEQ38872.1 - 4.3e-167 555.7 0.3 5.3e-167 555.4 0.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EEQ38872.1 - 2.7e-22 78.7 0.1 6.7e-22 77.4 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EEQ38872.1 - 2.1e-10 41.1 0.2 5e-07 30.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EEQ38872.1 - 3.4e-09 36.6 0.5 1.3e-06 28.2 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEQ38872.1 - 4.3e-05 23.5 0.1 0.09 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ38872.1 - 7e-05 23.1 0.1 0.22 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ38872.1 - 0.00048 20.5 0.1 0.0022 18.4 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EEQ38872.1 - 0.00094 18.5 0.1 0.0029 16.9 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.26 EEQ38872.1 - 0.001 18.8 0.0 0.71 9.6 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 EEQ38872.1 - 0.0013 18.1 0.2 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EEQ38872.1 - 0.0019 18.5 1.7 0.73 10.2 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EEQ38872.1 - 0.002 17.7 0.1 0.0048 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ38872.1 - 0.0038 17.8 0.1 0.026 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EEQ38872.1 - 0.0039 17.2 0.0 0.85 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EEQ38872.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EEQ38872.1 - 0.023 14.2 0.2 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region DnaB_C PF03796.15 EEQ38872.1 - 0.024 14.0 0.0 0.052 12.9 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 EEQ38872.1 - 0.028 14.1 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 EEQ38872.1 - 0.032 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EEQ38872.1 - 0.04 13.6 0.3 3.1 7.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EEQ38872.1 - 0.11 11.8 0.6 0.29 10.4 0.1 1.9 2 0 0 2 2 2 0 KaiC Sec1 PF00995.23 EEQ38873.1 - 1.2e-114 384.7 2.7 1.4e-114 384.5 2.7 1.0 1 0 0 1 1 1 1 Sec1 family MgtE_N PF03448.17 EEQ38873.1 - 0.035 14.7 1.6 0.14 12.7 0.7 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain T4_Gp59_C PF08994.10 EEQ38873.1 - 0.037 14.6 0.8 0.12 13.0 0.8 1.8 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term MlaA PF04333.13 EEQ38873.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 MlaA lipoprotein Zn_clus PF00172.18 EEQ38874.1 - 9.8e-05 22.4 15.1 0.00015 21.8 15.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Secretin_N_2 PF07655.13 EEQ38874.1 - 0.3 11.6 21.4 0.091 13.3 18.2 1.8 1 1 1 2 2 2 0 Secretin N-terminal domain TFIIA PF03153.13 EEQ38874.1 - 1.1 9.2 14.8 1.4 8.9 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.24 EEQ38876.1 - 5.8e-166 552.9 1.7 6.5e-166 552.8 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.24 EEQ38877.1 - 4.1e-51 173.7 0.0 5.2e-51 173.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EEQ38877.1 - 2.1e-16 59.9 6.8 5.2e-16 58.7 6.8 1.7 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EEQ38877.1 - 0.79 9.9 10.7 0.12 12.5 5.5 2.2 2 0 0 2 2 2 0 MYND finger His_Phos_1 PF00300.22 EEQ38878.1 - 3.4e-07 30.1 0.0 1.8e-06 27.8 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PI3_PI4_kinase PF00454.27 EEQ38879.1 - 8.3e-48 163.4 0.4 1.6e-47 162.4 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EEQ38879.1 - 3.9e-33 114.4 4.3 1.7e-20 73.2 0.3 3.0 2 1 0 2 2 2 2 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EEQ38879.1 - 6.4e-16 58.5 0.0 1.7e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 CoaE PF01121.20 EEQ38880.1 - 4.3e-57 192.7 0.0 5.2e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EEQ38880.1 - 0.00014 22.4 0.4 0.001 19.6 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ38880.1 - 0.05 13.8 0.0 0.27 11.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EEQ38880.1 - 0.051 13.8 0.1 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain ApbA_C PF08546.11 EEQ38881.1 - 8.3e-36 122.9 0.0 1.3e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EEQ38881.1 - 2.8e-27 95.3 0.0 4.8e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EEQ38881.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EEQ38881.1 - 0.16 11.8 0.4 5.8 6.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SET PF00856.28 EEQ38882.1 - 2.7e-15 57.2 0.0 4.3e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 SET domain Topoisom_bac PF01131.20 EEQ38883.1 - 3.1e-106 355.8 0.0 3.7e-106 355.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EEQ38883.1 - 1.5e-18 66.9 0.0 2.2e-17 63.2 0.0 2.4 2 0 0 2 2 2 1 Toprim domain zf-CCCH_4 PF18044.1 EEQ38884.1 - 1.7e-08 34.1 3.7 4.1e-08 32.8 3.7 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EEQ38884.1 - 5.1e-08 32.6 2.7 1.1e-07 31.6 2.7 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EEQ38884.1 - 8.3e-07 28.9 8.8 1.9e-06 27.7 8.8 1.7 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EEQ38884.1 - 0.011 16.4 0.4 0.022 15.5 0.4 1.5 1 0 0 1 1 1 0 Torus domain Nucleoporin_FG PF13634.6 EEQ38884.1 - 0.017 15.9 39.7 0.017 15.9 39.7 6.6 1 1 3 4 4 4 0 Nucleoporin FG repeat region zf-CCCH_3 PF15663.5 EEQ38884.1 - 0.038 14.2 0.0 0.076 13.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EEQ38884.1 - 1.7 9.2 6.5 3.7 8.2 6.5 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Arv1 PF04161.13 EEQ38885.1 - 8.4e-56 189.5 8.7 8.4e-56 189.5 8.7 1.6 2 0 0 2 2 2 1 Arv1-like family TraW_N PF12477.8 EEQ38885.1 - 3.4 7.7 7.6 13 5.9 1.4 2.6 2 0 0 2 2 2 0 Sex factor F TraW protein N terminal RSN1_7TM PF02714.15 EEQ38886.1 - 6.6e-79 265.1 24.7 6.6e-79 265.1 24.7 2.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEQ38886.1 - 8.3e-36 123.1 3.3 8.3e-36 123.1 3.3 2.7 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EEQ38886.1 - 4.2e-31 108.5 0.0 1.3e-30 106.9 0.0 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter HKR_ArcB_TM PF18415.1 EEQ38886.1 - 0.87 10.4 0.0 0.87 10.4 0.0 4.6 7 0 0 7 7 7 0 Histidine kinase receptor ArcB trans-membrane domain FTA4 PF13093.6 EEQ38887.1 - 1e-48 165.9 8.1 1.3e-48 165.6 8.1 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 KOG2701 PF09762.9 EEQ38887.1 - 0.14 12.4 0.1 0.14 12.4 0.1 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) DUF5617 PF18493.1 EEQ38887.1 - 0.3 11.2 2.1 0.37 10.9 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5617) DUF3835 PF12927.7 EEQ38887.1 - 0.44 11.4 2.9 6.9 7.6 2.3 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3835) Ribosomal_60s PF00428.19 EEQ38888.1 - 6.8e-27 93.9 9.9 7.9e-27 93.7 9.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein GP88 PF17338.2 EEQ38888.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Gene product 88 Ribosomal_S19 PF00203.21 EEQ38889.1 - 1.2e-32 111.6 0.0 2.3e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S19 CENP-P PF13096.6 EEQ38889.1 - 0.087 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P DUF5055 PF16478.5 EEQ38889.1 - 0.098 12.9 0.0 0.16 12.2 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5055) Mito_carr PF00153.27 EEQ38891.1 - 2.9e-53 177.8 4.1 4.2e-17 61.9 0.3 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.16 EEQ38891.1 - 0.0029 17.6 1.6 0.79 9.7 0.1 2.3 2 0 0 2 2 2 2 Colicin V production protein Tim17 PF02466.19 EEQ38891.1 - 1.5 9.3 8.5 24 5.4 8.5 2.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family GDPD_2 PF13653.6 EEQ38893.1 - 0.053 14.0 1.1 0.096 13.2 1.1 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family DUF1045 PF06299.12 EEQ38893.1 - 0.064 13.2 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) Zn_clus PF00172.18 EEQ38894.1 - 2.2e-06 27.7 6.4 5e-06 26.5 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 EEQ38895.1 - 1.3e-45 153.2 7.0 2.9e-15 56.0 0.5 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4011 PF13195.6 EEQ38895.1 - 0.11 12.4 1.2 2.3 8.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4011) Plasmodium_Vir PF05795.11 EEQ38895.1 - 0.16 11.4 0.9 0.28 10.6 0.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1689 PF07954.11 EEQ38895.1 - 0.81 10.1 5.8 0.66 10.4 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1689) Ribonucleas_3_3 PF14622.6 EEQ38896.1 - 6.7e-27 94.2 0.1 9e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EEQ38896.1 - 0.024 15.2 0.0 0.044 14.4 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease III domain DEAD PF00270.29 EEQ38897.1 - 5.6e-38 130.5 0.2 9.3e-38 129.7 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ38897.1 - 6.7e-29 100.5 0.1 2.6e-28 98.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ38897.1 - 6.9e-05 22.9 0.2 0.0002 21.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EEQ38897.1 - 0.00044 20.5 0.0 0.00098 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain CDC45 PF02724.14 EEQ38897.1 - 4.1 5.6 8.0 7.1 4.8 8.0 1.3 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_G PF04718.15 EEQ38898.1 - 1.8e-30 105.7 0.3 2.2e-30 105.4 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF4715 PF15835.5 EEQ38898.1 - 0.027 14.6 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Serinc PF03348.15 EEQ38899.1 - 2.1e-132 442.1 16.5 2.4e-132 441.9 16.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Ceramidase PF05875.12 EEQ38899.1 - 0.00064 19.2 1.4 0.00064 19.2 1.4 2.6 3 1 0 3 3 3 1 Ceramidase HGWP PF03578.15 EEQ38899.1 - 2.8 7.5 6.0 7.3 6.2 1.9 2.4 2 0 0 2 2 2 0 HGWP repeat PAXNEB PF05625.11 EEQ38900.1 - 2.3e-87 293.6 0.0 3.1e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein CbiX PF01903.17 EEQ38900.1 - 0.045 14.1 0.1 2.1 8.7 0.0 2.5 2 0 0 2 2 2 0 CbiX Abhydrolase_8 PF06259.12 EEQ38900.1 - 0.11 12.2 0.2 0.16 11.6 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase TLE_N PF03920.15 EEQ38902.1 - 0.0023 18.0 0.1 0.0032 17.5 0.1 1.3 1 0 0 1 1 1 1 Groucho/TLE N-terminal Q-rich domain SKA2 PF16740.5 EEQ38902.1 - 0.004 16.9 0.7 0.0072 16.1 0.7 1.4 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 DUF4618 PF15397.6 EEQ38902.1 - 0.0074 15.7 0.2 0.0098 15.3 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) Prominin PF05478.11 EEQ38902.1 - 0.011 13.8 0.6 0.013 13.4 0.6 1.0 1 0 0 1 1 1 0 Prominin COG2 PF06148.11 EEQ38902.1 - 0.045 13.8 0.3 0.069 13.2 0.3 1.2 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.10 EEQ38902.1 - 0.054 13.7 2.0 0.058 13.6 0.5 1.8 2 1 0 2 2 2 0 Cortexillin I, coiled coil ATG16 PF08614.11 EEQ38902.1 - 0.055 13.7 6.4 0.066 13.4 6.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) H-kinase_dim PF02895.14 EEQ38902.1 - 0.097 13.1 1.6 0.17 12.3 1.6 1.6 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain SlyX PF04102.12 EEQ38902.1 - 0.82 10.3 3.8 0.49 11.1 1.5 1.8 2 1 0 2 2 2 0 SlyX MCM PF00493.23 EEQ38903.1 - 9.9e-101 335.5 0.0 1.4e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ38903.1 - 2.1e-38 131.0 0.4 3.8e-38 130.2 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ38903.1 - 1.5e-26 92.7 3.6 1.5e-26 92.7 3.6 2.7 3 0 0 3 3 3 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ38903.1 - 1.6e-19 70.4 0.1 1.1e-18 67.7 0.0 2.6 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ38903.1 - 5.3e-06 26.0 0.0 0.00023 20.6 0.0 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ38903.1 - 2e-05 24.6 0.0 8.2e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEQ38903.1 - 8.7e-05 22.4 0.0 0.0038 17.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ38903.1 - 0.036 13.8 0.2 2.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.6 EEQ38903.1 - 0.16 12.4 0.5 2.6 8.4 0.1 2.9 2 1 0 2 2 2 0 AAA ATPase domain DUF5321 PF17254.2 EEQ38904.1 - 8.2e-11 41.6 0.1 1e-10 41.3 0.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) HK_sensor PF16750.5 EEQ38904.1 - 0.02 15.2 0.4 3 8.2 0.1 2.1 1 1 1 2 2 2 0 Sensor domain of 2-component histidine kinase Fer4_NifH PF00142.18 EEQ38904.1 - 0.073 12.5 0.6 0.09 12.2 0.6 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1751 PF08551.10 EEQ38905.1 - 7.1e-16 58.6 1.6 1.2e-15 57.9 0.1 2.2 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EEQ38905.1 - 0.39 10.7 8.0 0.97 9.4 8.0 1.6 1 0 0 1 1 1 0 Rhomboid family DUF3149 PF11346.8 EEQ38905.1 - 7.1 6.3 6.9 38 4.0 1.8 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3149) TRAPPC-Trs85 PF12739.7 EEQ38906.1 - 1.1e-102 344.0 8.9 2.4e-102 342.9 8.9 1.5 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit CUE PF02845.16 EEQ38906.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 CUE domain DUF4478 PF14793.6 EEQ38906.1 - 0.08 12.8 0.0 0.97 9.3 0.0 2.3 1 1 1 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases Rax2 PF12768.7 EEQ38907.1 - 2.8e-58 196.9 0.3 2.8e-58 196.9 0.3 5.3 4 1 1 5 5 5 1 Cortical protein marker for cell polarity Sortilin-Vps10 PF15902.5 EEQ38908.1 - 4.7e-219 727.7 5.8 3.1e-123 411.9 1.7 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EEQ38908.1 - 6.1e-74 248.0 24.1 5.7e-44 150.5 2.4 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EEQ38908.1 - 1.3e-09 36.6 31.2 0.56 10.4 0.3 10.5 10 0 0 10 10 10 5 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EEQ38908.1 - 0.011 15.8 1.8 2 8.4 0.0 4.3 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.6 EEQ38908.1 - 0.12 11.6 0.7 9.3 5.4 0.1 3.6 3 1 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 preSET_CXC PF18264.1 EEQ38908.1 - 0.48 10.9 9.4 5.5 7.5 0.8 2.7 2 0 0 2 2 2 0 CXC domain FF PF01846.19 EEQ38910.1 - 3.7e-31 107.0 7.8 1.2e-09 38.1 0.3 5.2 4 0 0 4 4 4 4 FF domain WW PF00397.26 EEQ38910.1 - 4.1e-17 62.0 22.5 2.7e-09 37.0 2.8 2.9 3 0 0 3 3 3 2 WW domain Phage_T7_Capsid PF05396.11 EEQ38910.1 - 0.0053 17.1 0.2 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 Phage T7 capsid assembly protein Glyco_hyd_101C PF17451.2 EEQ38910.1 - 0.014 15.6 6.7 0.61 10.4 0.8 3.1 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain RhoGAP-FF1 PF16512.5 EEQ38910.1 - 0.03 15.0 12.6 2 9.2 0.0 4.7 3 2 1 4 4 4 0 p190-A and -B Rho GAPs FF domain ApbA_C PF08546.11 EEQ38910.1 - 0.061 13.5 1.3 0.39 10.9 0.1 2.7 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal HD PF01966.22 EEQ38910.1 - 0.12 12.7 0.6 0.73 10.1 0.2 2.5 2 0 0 2 2 2 0 HD domain DUF948 PF06103.11 EEQ38910.1 - 6.4 7.1 5.6 7 7.0 1.2 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ARPC4 PF05856.12 EEQ38911.1 - 1.4e-43 148.4 4.1 1.6e-43 148.2 4.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Fungal_trans PF04082.18 EEQ38912.1 - 1.8e-22 79.6 2.6 5.5e-22 78.1 2.6 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ38912.1 - 2.6e-05 24.3 8.4 5.5e-05 23.2 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro81C PF17652.1 EEQ38914.1 - 1.2e-151 504.9 11.3 1.7e-151 504.4 11.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EEQ38914.1 - 1.6e-86 290.4 5.8 3.6e-86 289.3 5.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain CTD_bind PF04818.13 EEQ38914.1 - 0.15 12.9 0.1 0.43 11.4 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase II-binding domain. DHHC PF01529.20 EEQ38916.1 - 2.7e-33 114.9 11.1 2.7e-33 114.9 11.1 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase OST3_OST6 PF04756.13 EEQ38916.1 - 0.057 12.8 0.3 0.057 12.8 0.3 1.8 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Bestrophin PF01062.21 EEQ38916.1 - 0.12 11.8 1.7 0.14 11.5 0.1 1.8 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel LPG_synthase_TM PF03706.13 EEQ38916.1 - 9.4 5.7 17.6 1.7 8.1 8.1 2.1 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region TRM PF02005.16 EEQ38918.1 - 1.4e-116 389.8 0.0 2e-116 389.3 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EEQ38918.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein DUF2946 PF11162.8 EEQ38918.1 - 0.056 14.1 0.1 0.22 12.2 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TrmK PF04816.12 EEQ38918.1 - 0.06 12.9 0.2 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase Desulfoferrod_N PF06397.12 EEQ38918.1 - 0.065 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain DUF913 PF06025.12 EEQ38918.1 - 0.68 8.9 3.7 21 3.9 3.1 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) SAPS PF04499.15 EEQ38918.1 - 1.7 7.4 4.8 18 4.0 3.4 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 EEQ38918.1 - 2.2 6.9 13.3 7 5.3 0.1 2.2 2 0 0 2 2 2 0 Presenilin SpoIIIAH PF12685.7 EEQ38918.1 - 2.4 7.9 12.2 5.8 6.7 4.4 2.5 3 0 0 3 3 3 0 SpoIIIAH-like protein Neur_chan_memb PF02932.16 EEQ38918.1 - 2.9 7.9 5.5 25 4.8 2.8 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2052 PF09747.9 EEQ38918.1 - 3.3 7.8 21.4 4.6 7.3 10.5 3.0 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) BORG_CEP PF14957.6 EEQ38918.1 - 3.9 8.7 9.9 58 4.9 0.0 3.0 3 0 0 3 3 3 0 Cdc42 effector DUF4050 PF13259.6 EEQ38918.1 - 5.2 7.3 10.5 6.1 7.1 3.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4050) CPSF100_C PF13299.6 EEQ38918.1 - 6.2 7.0 17.1 1.5 9.0 5.0 2.8 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.9 EEQ38918.1 - 6.3 5.2 10.6 6.3 5.2 1.1 2.4 2 1 0 2 2 2 0 Macoilin family Plasmodium_Vir PF05795.11 EEQ38918.1 - 7.6 5.8 7.9 14 5.0 4.3 2.1 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Ydc2-catalyt PF09159.10 EEQ38919.1 - 3.1e-46 158.4 0.0 4.5e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Spike_rec_bind PF09408.10 EEQ38919.1 - 0.011 15.4 0.2 0.017 14.9 0.2 1.2 1 0 0 1 1 1 0 Spike receptor binding domain Flavoprotein PF02441.19 EEQ38920.1 - 1.1e-49 168.3 0.1 1.8e-49 167.5 0.1 1.4 1 0 0 1 1 1 1 Flavoprotein Nop14 PF04147.12 EEQ38920.1 - 0.00051 18.4 34.3 0.00098 17.5 34.3 1.4 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 EEQ38920.1 - 0.11 10.7 29.4 0.2 9.9 29.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 EEQ38920.1 - 0.31 9.4 34.2 0.48 8.8 34.2 1.2 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 EEQ38920.1 - 0.4 10.1 41.9 0.83 9.0 41.9 1.5 1 0 0 1 1 1 0 SDA1 Peptidase_S24 PF00717.23 EEQ38921.1 - 1.7e-09 37.5 0.0 2.6e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like adh_short PF00106.25 EEQ38922.1 - 2.8e-33 115.0 0.0 3.5e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ38922.1 - 3.2e-23 82.5 0.0 4e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EEQ38922.1 - 0.00015 21.3 0.0 0.00024 20.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EEQ38922.1 - 0.009 15.9 0.1 0.014 15.3 0.1 1.3 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EEQ38922.1 - 0.11 11.8 0.1 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase PRKCSH-like PF12999.7 EEQ38924.1 - 4.6e-52 176.3 4.5 4.6e-52 176.3 4.5 2.1 1 1 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EEQ38924.1 - 8.7e-45 152.2 0.7 4.4e-44 149.9 0.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Tup_N PF08581.10 EEQ38924.1 - 0.036 14.4 1.2 0.036 14.4 1.2 2.5 2 0 0 2 2 2 0 Tup N-terminal HMMR_N PF15905.5 EEQ38924.1 - 0.14 11.6 18.4 0.074 12.5 14.8 2.0 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 EEQ38924.1 - 0.22 10.4 18.5 0.11 11.4 16.2 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF349 PF03993.12 EEQ38924.1 - 0.26 11.6 11.2 0.055 13.8 6.5 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF1640 PF07798.11 EEQ38924.1 - 0.44 10.6 10.9 0.89 9.6 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FapA PF03961.13 EEQ38924.1 - 0.88 8.1 14.0 0.9 8.1 10.4 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A Fib_alpha PF08702.10 EEQ38924.1 - 1.5 9.0 17.2 0.095 12.9 8.6 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CR6_interact PF10147.9 EEQ38924.1 - 4.1 7.1 19.1 2.7 7.7 1.5 2.7 2 1 1 3 3 3 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF2252 PF10009.9 EEQ38924.1 - 4.2 6.3 7.6 1.2 8.2 4.8 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) MscS_porin PF12795.7 EEQ38924.1 - 4.3 6.8 30.9 0.6 9.6 15.8 2.5 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 EEQ38924.1 - 4.5 6.5 18.0 1.7 8.0 13.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Peptidase_S46 PF10459.9 EEQ38924.1 - 6.3 5.3 11.8 9.2 4.8 11.8 1.3 1 0 0 1 1 1 0 Peptidase S46 MetOD2 PF18548.1 EEQ38924.1 - 7.9 6.7 9.8 2.4 8.3 0.3 3.0 3 0 0 3 3 3 0 Metanogen output domain 2 BUD22 PF09073.10 EEQ38925.1 - 5.3e-63 213.9 47.8 7.6e-63 213.3 47.8 1.2 1 0 0 1 1 1 1 BUD22 TRM13 PF05206.14 EEQ38926.1 - 6.4e-60 202.9 6.0 2.4e-50 171.5 0.1 3.5 2 1 1 3 3 3 2 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 EEQ38926.1 - 1.2e-13 50.6 1.2 2.8e-13 49.4 1.2 1.7 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 EEQ38926.1 - 3.4e-09 36.4 0.4 6.4e-09 35.5 0.4 1.5 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 EEQ38926.1 - 0.00041 20.4 0.9 0.00041 20.4 0.9 2.3 1 1 1 2 2 2 1 Methyltransferase domain TCTP PF00838.17 EEQ38927.1 - 1.7e-72 243.2 0.9 1.9e-72 243.0 0.9 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mlp PF03304.13 EEQ38927.1 - 0.078 13.2 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Mlp lipoprotein family DPPIV_N PF00930.21 EEQ38928.1 - 2.9e-98 328.9 0.8 4e-98 328.4 0.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EEQ38928.1 - 1e-46 159.1 1.3 2.5e-46 157.8 1.3 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EEQ38928.1 - 6.6e-06 26.9 0.1 0.00041 21.0 0.0 3.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EEQ38928.1 - 0.0031 17.1 0.6 0.01 15.5 0.4 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase_phd PF10503.9 EEQ38928.1 - 0.0068 15.9 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase AXE1 PF05448.12 EEQ38928.1 - 0.013 14.2 0.0 0.026 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) LIP PF03583.14 EEQ38928.1 - 0.027 13.8 0.0 0.075 12.3 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase Abhydrolase_1 PF00561.20 EEQ38928.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Response_reg PF00072.24 EEQ38929.1 - 6.6e-29 100.3 0.1 1.3e-28 99.4 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EEQ38929.1 - 3.7e-25 88.6 0.1 1.4e-19 70.7 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EEQ38929.1 - 4.9e-14 52.1 2.2 2.4e-13 49.9 0.6 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EEQ38929.1 - 0.00092 19.5 0.0 0.1 13.0 0.0 3.1 3 0 0 3 3 3 1 HAMP domain Big_3_4 PF13754.6 EEQ38929.1 - 0.074 12.8 0.0 2.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function Tetrabrachion PF11401.8 EEQ38929.1 - 0.16 12.0 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Tetrabrachion Asp PF00026.23 EEQ38930.1 - 3.5e-23 82.5 0.0 4e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TPT PF03151.16 EEQ38931.1 - 3.4e-14 52.9 21.3 4.8e-14 52.4 21.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EEQ38931.1 - 4e-12 46.0 16.3 4e-12 46.0 16.3 1.3 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 EEQ38931.1 - 4e-07 29.6 15.9 6.1e-07 29.0 15.9 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 EEQ38931.1 - 2.7e-06 27.6 40.1 9.4e-06 25.8 18.0 3.1 2 1 0 2 2 2 2 EamA-like transporter family DUF1129 PF06570.11 EEQ38931.1 - 0.36 10.3 8.5 0.024 14.2 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Sec1 PF00995.23 EEQ38932.1 - 1.6e-84 285.2 0.0 2e-84 284.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF4383 PF14325.6 EEQ38933.1 - 0.0057 16.9 3.0 0.0083 16.4 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4383) MTABC_N PF16185.5 EEQ38933.1 - 0.0071 15.9 2.0 0.011 15.3 2.0 1.4 1 1 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region ABC_membrane PF00664.23 EEQ38934.1 - 1.2e-85 287.5 25.8 5.8e-45 154.1 11.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ38934.1 - 1.1e-18 68.1 0.0 2.9e-18 66.7 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EEQ38934.1 - 0.0024 17.4 0.1 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain UPF0093 PF03653.13 EEQ38934.1 - 0.074 13.3 3.7 0.089 13.0 0.9 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) MMR_HSR1 PF01926.23 EEQ38934.1 - 0.078 13.1 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ38934.1 - 0.089 12.7 0.6 0.3 11.0 0.6 1.9 1 1 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EEQ38934.1 - 0.19 11.5 0.6 0.6 9.9 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EEQ38934.1 - 0.24 11.5 0.0 0.24 11.5 0.0 2.2 2 1 0 2 2 2 0 Dynamin family LapA_dom PF06305.11 EEQ38934.1 - 0.48 10.3 2.2 26 4.7 0.2 4.0 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain AAA_23 PF13476.6 EEQ38934.1 - 1.4 9.4 0.0 1.4 9.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EEQ38935.1 - 7.5e-30 104.2 0.1 1.4e-29 103.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EEQ38935.1 - 2.4e-09 36.9 1.5 2.2e-08 33.8 1.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EEQ38935.1 - 0.0014 18.6 0.3 1.7 8.6 0.0 3.2 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EEQ38935.1 - 0.0053 16.8 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ38935.1 - 0.009 16.4 0.3 0.02 15.3 0.2 1.6 1 1 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 EEQ38935.1 - 0.042 13.6 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 EEQ38935.1 - 0.079 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ38935.1 - 0.094 13.0 0.6 1.4 9.2 0.6 2.2 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 EEQ38936.1 - 0.0065 17.3 1.1 0.72 10.8 1.1 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Gemin6 PF06372.12 EEQ38936.1 - 0.088 12.3 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Gemin6 protein Avl9 PF09794.9 EEQ38937.1 - 3.3e-122 407.8 5.1 4.3e-122 407.5 5.1 1.1 1 0 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EEQ38937.1 - 5.4e-10 39.3 4.2 7.2e-10 38.9 2.5 2.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 EEQ38937.1 - 9e-06 25.8 1.8 9e-06 25.8 1.8 1.7 2 0 0 2 2 2 1 DENN (AEX-3) domain SPA PF08616.10 EEQ38937.1 - 0.00022 21.2 8.5 0.065 13.2 0.0 3.0 4 0 0 4 4 4 2 Stabilization of polarity axis DUF5470 PF17564.2 EEQ38937.1 - 0.12 12.5 0.1 0.28 11.4 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5470) Sod_Ni PF09055.11 EEQ38937.1 - 0.17 12.5 0.1 0.41 11.2 0.1 1.7 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase Redoxin PF08534.10 EEQ38938.1 - 4.3e-27 94.6 0.0 4.9e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EEQ38938.1 - 0.0019 18.1 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Pro_isomerase PF00160.21 EEQ38939.1 - 6.2e-48 163.1 0.1 7.1e-48 162.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S14 PF00253.21 EEQ38941.1 - 2.2e-16 59.4 3.1 2.4e-16 59.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e RIBIOP_C PF04950.12 EEQ38942.1 - 1.8e-101 339.4 1.0 2.5e-101 339.0 0.0 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EEQ38942.1 - 2.5e-19 69.1 0.0 7.1e-19 67.7 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain zf-C2H2_2 PF12756.7 EEQ38943.1 - 2.3e-32 111.4 1.5 1.6e-29 102.2 0.5 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 EEQ38943.1 - 0.0093 14.5 1.0 1.9 6.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF629) zf-C2H2_3rep PF18868.1 EEQ38943.1 - 0.032 14.9 0.2 26 5.5 0.0 3.2 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 EEQ38943.1 - 0.061 13.8 14.3 0.08 13.4 0.2 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.12 EEQ38943.1 - 0.087 13.1 1.7 5.2 7.3 0.0 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Actin_micro PF17003.5 EEQ38943.1 - 0.12 11.5 0.6 5 6.2 0.0 2.5 2 1 0 2 2 2 0 Putative actin-like family zf-C2H2_4 PF13894.6 EEQ38943.1 - 5.1 8.2 9.7 1.9 9.5 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-BED PF02892.15 EEQ38943.1 - 5.3 7.1 6.5 0.83 9.7 0.5 2.7 3 0 0 3 3 3 0 BED zinc finger DnaJ_C PF01556.18 EEQ38944.1 - 1.1e-27 97.0 0.0 2.9e-27 95.6 0.0 1.7 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ38944.1 - 9.4e-22 76.9 2.0 1.8e-21 76.0 2.0 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEQ38944.1 - 2.7e-07 30.8 19.1 4.8e-07 30.0 19.1 1.4 1 0 0 1 1 1 1 DnaJ central domain Macoilin PF09726.9 EEQ38944.1 - 7.8 4.9 9.4 11 4.4 9.4 1.1 1 0 0 1 1 1 0 Macoilin family Vac14_Fig4_bd PF11916.8 EEQ38945.1 - 4.1e-66 222.0 12.8 8.1e-66 221.1 12.8 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EEQ38945.1 - 5.3e-35 119.9 1.7 1.1e-34 118.9 0.2 2.4 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EEQ38945.1 - 0.0015 18.8 0.0 0.082 13.3 0.0 3.5 2 1 1 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EEQ38945.1 - 0.0023 18.4 0.0 0.31 11.6 0.0 3.4 2 1 1 3 3 3 1 HEAT-like repeat HEAT PF02985.22 EEQ38945.1 - 0.0026 17.9 0.0 0.036 14.3 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat Cnd1 PF12717.7 EEQ38945.1 - 0.059 13.4 0.1 0.059 13.4 0.1 3.5 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Pyr_redox_2 PF07992.14 EEQ38947.1 - 3.1e-09 36.5 0.0 5.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ38947.1 - 3.5e-05 23.8 0.0 0.00011 22.2 0.0 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EEQ38947.1 - 0.0059 16.8 0.0 0.059 13.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EEQ38947.1 - 0.031 13.5 0.2 8.9 5.5 0.1 2.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EEQ38947.1 - 0.043 13.9 0.0 39 4.3 0.0 3.1 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 EEQ38947.1 - 0.074 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 EEQ38947.1 - 0.15 11.2 0.0 7.3 5.6 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Lipase_3 PF01764.25 EEQ38948.1 - 1.5e-33 115.6 0.0 2.4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EEQ38948.1 - 0.00034 21.3 0.5 0.00034 21.3 0.5 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EEQ38948.1 - 0.00095 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EEQ38948.1 - 0.0089 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EEQ38948.1 - 0.018 14.7 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 EEQ38948.1 - 0.034 13.7 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EEQ38948.1 - 0.048 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ38948.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 EEQ38948.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DASH_Ask1 PF08655.10 EEQ38949.1 - 3.7e-23 81.2 0.0 7.4e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Rxt3 PF08642.10 EEQ38949.1 - 1.5 9.6 4.8 0.47 11.2 0.2 2.5 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 Fungal_trans PF04082.18 EEQ38950.1 - 5.2e-36 124.0 8.3 1.1e-35 123.0 8.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ38950.1 - 4.5e-10 39.5 12.0 9.1e-10 38.5 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L29 PF00831.23 EEQ38950.1 - 0.0014 18.6 0.1 0.073 13.1 0.6 2.5 2 0 0 2 2 2 1 Ribosomal L29 protein MCM_OB PF17207.3 EEQ38950.1 - 0.14 12.0 3.9 0.43 10.4 3.9 1.7 1 0 0 1 1 1 0 MCM OB domain Complex1_LYR PF05347.15 EEQ38951.1 - 5.9e-16 58.3 0.4 7.2e-16 58.0 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ38951.1 - 2.4e-05 25.0 0.1 2.8e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EEQ38951.1 - 0.028 15.0 0.1 0.035 14.7 0.1 1.2 1 0 0 1 1 1 0 Complex1_LYR-like RhoGAP PF00620.27 EEQ38952.1 - 6.7e-41 139.6 0.0 1.9e-40 138.1 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EEQ38952.1 - 5.8e-14 52.1 23.1 2e-08 34.3 6.5 2.4 2 0 0 2 2 2 2 LIM domain ERM PF00769.19 EEQ38952.1 - 0.0061 16.4 6.3 0.0061 16.4 6.3 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family BRE1 PF08647.11 EEQ38952.1 - 0.13 12.3 11.0 0.22 11.6 8.4 2.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 EEQ38952.1 - 0.33 11.5 7.7 1.1 9.8 7.7 1.9 1 0 0 1 1 1 0 Apg6 coiled-coil region ZapB PF06005.12 EEQ38952.1 - 1.4 9.4 13.4 0.14 12.6 5.8 2.6 1 1 1 2 2 2 0 Cell division protein ZapB IQCJ-SCHIP1 PF15157.6 EEQ38952.1 - 1.9 8.3 7.0 0.41 10.5 2.3 2.3 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif TPR_MLP1_2 PF07926.12 EEQ38952.1 - 2.9 8.0 13.3 2.1 8.4 10.8 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 EEQ38952.1 - 4.8 7.6 10.1 5 7.6 7.7 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) JIP_LZII PF16471.5 EEQ38952.1 - 9.3 6.5 11.8 9.8 6.4 9.4 2.4 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Anp1 PF03452.14 EEQ38953.1 - 3.3e-111 370.9 0.0 4.5e-111 370.5 0.0 1.2 1 0 0 1 1 1 1 Anp1 SMC_N PF02463.19 EEQ38954.1 - 3.9e-76 255.3 0.0 4.2e-41 140.8 0.0 2.8 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEQ38954.1 - 9.3e-17 61.4 1.3 6.8e-16 58.6 0.1 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EEQ38954.1 - 2.6e-11 44.4 22.3 2.6e-11 44.4 22.3 7.5 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.6 EEQ38954.1 - 4.6e-07 29.9 16.6 5.4e-05 23.1 0.3 3.9 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEQ38954.1 - 5.9e-05 22.9 10.2 5.9e-05 22.9 10.2 4.4 2 2 1 3 3 1 1 AAA ATPase domain AAA_29 PF13555.6 EEQ38954.1 - 7.1e-05 22.5 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain EzrA PF06160.12 EEQ38954.1 - 8.5e-05 20.9 25.1 8.5e-05 20.9 25.1 6.2 2 2 3 6 6 6 3 Septation ring formation regulator, EzrA AAA_13 PF13166.6 EEQ38954.1 - 0.0011 17.8 103.6 0.0017 17.1 13.0 5.1 3 2 0 5 5 5 3 AAA domain HMMR_N PF15905.5 EEQ38954.1 - 0.0027 17.2 32.4 0.0027 17.2 32.4 6.3 2 2 2 6 6 6 2 Hyaluronan mediated motility receptor N-terminal Nup54_57_C PF18570.1 EEQ38954.1 - 0.0037 16.8 0.1 0.1 12.2 0.0 3.4 2 0 0 2 2 2 1 NUP57/Nup54 C-terminal domain Fez1 PF06818.15 EEQ38954.1 - 0.0085 16.6 4.7 0.0085 16.6 4.7 6.6 3 2 2 6 6 6 2 Fez1 TolA_bind_tri PF16331.5 EEQ38954.1 - 0.05 13.7 0.4 0.05 13.7 0.4 8.4 6 2 3 9 9 9 0 TolA binding protein trimerisation DUF2721 PF11026.8 EEQ38954.1 - 0.11 12.4 4.7 2.6 7.9 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF2721) Spc7 PF08317.11 EEQ38954.1 - 0.35 9.7 115.7 0.039 12.8 21.8 7.2 2 2 5 7 7 7 0 Spc7 kinetochore protein Halo_GVPC PF05465.13 EEQ38954.1 - 0.56 10.5 3.2 2 8.7 0.1 2.8 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat DUF3584 PF12128.8 EEQ38954.1 - 0.62 7.5 90.9 0.85 7.1 36.7 4.5 2 2 2 4 4 4 0 Protein of unknown function (DUF3584) Pex24p PF06398.11 EEQ38955.1 - 4.5e-91 305.6 8.1 5.1e-91 305.4 8.1 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Prp18 PF02840.15 EEQ38956.1 - 4.6e-39 133.7 0.4 4.6e-39 133.7 0.4 1.9 2 1 0 2 2 2 1 Prp18 domain FAM209 PF15206.6 EEQ38956.1 - 0.063 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 FAM209 family Ribosomal_L38e PF01781.18 EEQ38957.1 - 1.1e-28 99.1 3.1 1.3e-28 98.9 3.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIIF_beta_N PF17683.1 EEQ38958.1 - 1.2e-38 132.8 2.3 2.6e-38 131.8 2.3 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EEQ38958.1 - 4.4e-30 103.6 1.0 1e-29 102.4 1.0 1.6 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EEQ38958.1 - 0.0067 17.2 0.9 0.014 16.2 0.7 1.9 1 1 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Prenyltransf PF01255.19 EEQ38958.1 - 0.14 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase ATE_C PF04377.15 EEQ38959.1 - 5.8e-50 169.4 0.9 7.7e-50 169.0 0.1 1.6 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EEQ38959.1 - 8.8e-25 86.9 2.0 2e-24 85.8 2.0 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 EEQ38959.1 - 0.012 15.8 0.2 0.034 14.3 0.2 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LicD PF04991.13 EEQ38960.1 - 1.4e-31 110.4 5.2 1.3e-24 87.7 0.3 3.2 2 1 0 3 3 3 2 LicD family TBCA PF02970.16 EEQ38960.1 - 0.027 14.8 0.4 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Tubulin binding cofactor A COX6A PF02046.15 EEQ38961.1 - 1.4e-41 141.5 6.2 1.9e-41 141.1 6.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.32 EEQ38962.1 - 2.2e-15 56.8 1.3 0.0041 17.9 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ38962.1 - 0.062 13.6 0.2 14 6.1 0.0 3.7 2 2 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S26e PF01283.19 EEQ38963.1 - 5.2e-53 178.0 11.0 6.1e-53 177.8 11.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e 2-Hacid_dh_C PF02826.19 EEQ38965.1 - 3.7e-39 133.9 0.0 6.1e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ38965.1 - 2.1e-13 50.1 0.0 5.5e-13 48.7 0.0 1.7 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 EEQ38965.1 - 3e-06 27.7 0.0 5.9e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EEQ38965.1 - 7.2e-05 23.0 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EEQ38965.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rossmann-like PF10727.9 EEQ38965.1 - 0.0015 18.4 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain NAD_binding_7 PF13241.6 EEQ38965.1 - 0.0017 18.8 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 EEQ38965.1 - 0.0032 17.7 0.0 0.0053 17.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 EEQ38965.1 - 0.0049 16.5 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 EEQ38965.1 - 0.039 14.8 0.0 0.41 11.5 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Pyr_redox_2 PF07992.14 EEQ38965.1 - 0.05 12.8 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EEQ38965.1 - 0.082 12.9 0.0 5.9 6.9 0.0 2.6 2 0 0 2 2 2 0 Rieske-like [2Fe-2S] domain XdhC_C PF13478.6 EEQ38965.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain Nitro_FeMo-Co PF02579.17 EEQ38965.1 - 0.15 12.4 0.0 3.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor SHD1 PF03983.12 EEQ38966.1 - 3.2e-32 110.1 0.0 5.5e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 EEQ38966.1 - 2.1e-14 52.8 0.3 1.2e-13 50.4 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EEQ38966.1 - 2e-12 46.8 0.8 3.5e-11 42.8 0.1 2.9 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 EEQ38966.1 - 2.1e-09 36.9 0.1 1.2e-07 31.3 0.1 3.0 3 0 0 3 3 3 1 Variant SH3 domain SAM_4 PF18017.1 EEQ38966.1 - 0.0021 18.0 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MT-A70 PF05063.14 EEQ38967.1 - 1.2e-47 162.0 0.0 2e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 MT-A70 DUF962 PF06127.11 EEQ38968.1 - 4.2e-25 87.6 0.7 8.3e-25 86.7 0.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF1282 PF06930.12 EEQ38968.1 - 0.059 13.2 7.0 0.25 11.1 1.5 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1282) STT3 PF02516.14 EEQ38969.1 - 2.1e-145 485.4 43.8 1.5e-141 472.7 40.9 2.2 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.6 EEQ38969.1 - 0.0011 19.3 16.1 0.0011 19.3 16.1 3.6 2 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase FYVE PF01363.21 EEQ38970.1 - 1.9e-15 56.8 6.6 3.5e-15 55.9 6.6 1.5 1 0 0 1 1 1 1 FYVE zinc finger HNH_5 PF14279.6 EEQ38970.1 - 0.015 15.1 1.3 0.042 13.7 1.3 1.8 1 0 0 1 1 1 0 HNH endonuclease IBR PF01485.21 EEQ38970.1 - 0.065 13.5 1.9 0.16 12.2 1.9 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 EEQ38970.1 - 0.16 12.1 10.2 0.35 11.1 10.2 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger Sdh_cyt PF01127.22 EEQ38971.1 - 2.1e-28 98.8 1.2 2.9e-28 98.3 1.2 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Hap4_Hap_bind PF10297.9 EEQ38973.1 - 2.8e-06 27.3 9.5 2.8e-06 27.3 9.5 2.4 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Tmemb_cc2 PF10267.9 EEQ38973.1 - 0.32 10.1 2.4 0.51 9.4 2.4 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RAP1 PF07218.11 EEQ38973.1 - 4 5.6 8.7 6.1 5.0 8.7 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cmc1 PF08583.10 EEQ38974.1 - 6.6e-17 61.3 4.3 9.8e-17 60.7 4.3 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 EEQ38974.1 - 0.0012 19.0 0.9 0.0015 18.7 0.9 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Spc24 PF08286.11 EEQ38975.1 - 3e-26 91.7 5.6 8.5e-24 83.8 1.0 2.2 2 0 0 2 2 2 2 Spc24 subunit of Ndc80 DUF4164 PF13747.6 EEQ38975.1 - 0.0025 18.1 8.7 0.014 15.6 0.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4164) CENP-F_leu_zip PF10473.9 EEQ38975.1 - 0.0034 17.4 8.8 0.016 15.2 1.6 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dad2 PF08654.10 EEQ38975.1 - 0.0043 17.4 3.5 0.12 12.8 2.9 2.7 1 1 0 1 1 1 1 DASH complex subunit Dad2 LPP PF04728.13 EEQ38975.1 - 0.0048 17.3 2.5 0.049 14.0 0.0 2.5 2 1 0 2 2 2 1 Lipoprotein leucine-zipper DUF5082 PF16888.5 EEQ38975.1 - 0.0051 17.1 5.1 0.07 13.4 0.5 2.5 1 1 2 3 3 3 2 Domain of unknown function (DUF5082) Cep57_MT_bd PF06657.13 EEQ38975.1 - 0.006 17.0 4.9 0.45 11.0 0.2 2.4 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 FlaC_arch PF05377.11 EEQ38975.1 - 0.0078 16.6 8.5 0.033 14.6 0.8 3.3 4 0 0 4 4 3 1 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 EEQ38975.1 - 0.011 15.7 1.0 0.011 15.7 1.0 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.8 EEQ38975.1 - 0.018 14.4 0.6 0.018 14.4 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Swi5 PF07061.11 EEQ38975.1 - 0.018 15.1 2.8 0.042 13.9 0.2 2.3 2 1 0 2 2 2 0 Swi5 DUF16 PF01519.16 EEQ38975.1 - 0.031 14.8 2.7 0.13 12.7 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4200 PF13863.6 EEQ38975.1 - 0.033 14.6 0.8 0.033 14.6 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4988 PF16378.5 EEQ38975.1 - 0.033 13.9 0.4 0.06 13.0 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function End3 PF12761.7 EEQ38975.1 - 0.037 14.2 5.1 2.3 8.4 0.6 2.1 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF155 PF02582.14 EEQ38975.1 - 0.042 13.9 9.2 1.4 9.0 3.7 2.2 1 1 1 2 2 2 0 Uncharacterised ACR, YagE family COG1723 bZIP_1 PF00170.21 EEQ38975.1 - 0.044 13.9 1.8 0.044 13.9 1.8 2.8 2 1 1 3 3 2 0 bZIP transcription factor DUF4795 PF16043.5 EEQ38975.1 - 0.052 13.1 5.1 0.1 12.2 5.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Prefoldin_2 PF01920.20 EEQ38975.1 - 0.055 13.4 8.9 0.063 13.2 2.1 2.6 1 1 1 3 3 3 0 Prefoldin subunit XhlA PF10779.9 EEQ38975.1 - 0.061 13.5 1.2 0.061 13.5 1.2 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF948 PF06103.11 EEQ38975.1 - 0.084 13.1 1.3 0.31 11.3 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) MscS_porin PF12795.7 EEQ38975.1 - 0.091 12.3 8.3 0.17 11.4 8.3 1.3 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4618 PF15397.6 EEQ38975.1 - 0.11 11.9 8.6 0.25 10.7 8.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) FlxA PF14282.6 EEQ38975.1 - 0.11 12.5 3.1 0.65 10.0 0.1 2.3 2 0 0 2 2 2 0 FlxA-like protein CENP-H PF05837.12 EEQ38975.1 - 0.11 12.9 10.7 0.28 11.6 1.6 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Sec34 PF04136.15 EEQ38975.1 - 0.15 11.9 5.1 0.28 11.0 2.4 2.1 1 1 1 2 2 2 0 Sec34-like family Phage_GP20 PF06810.11 EEQ38975.1 - 0.16 11.8 2.9 0.59 9.9 2.3 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 Troponin PF00992.20 EEQ38975.1 - 0.16 12.3 7.8 0.19 12.0 1.5 2.1 1 1 1 2 2 2 0 Troponin MbeD_MobD PF04899.12 EEQ38975.1 - 0.2 11.8 2.5 2.1 8.5 0.2 2.3 2 0 0 2 2 2 0 MbeD/MobD like DUF1664 PF07889.12 EEQ38975.1 - 0.22 11.6 6.1 0.89 9.6 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 EEQ38975.1 - 0.23 11.8 4.9 0.15 12.4 0.6 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain ZapB PF06005.12 EEQ38975.1 - 0.27 11.7 7.7 0.12 12.8 1.3 2.3 2 0 0 2 2 2 0 Cell division protein ZapB Fez1 PF06818.15 EEQ38975.1 - 0.31 11.5 8.5 0.57 10.6 8.5 1.5 1 1 0 1 1 1 0 Fez1 Seryl_tRNA_N PF02403.22 EEQ38975.1 - 0.34 11.2 10.7 1 9.6 1.2 2.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4665 PF15679.5 EEQ38975.1 - 0.42 11.3 5.7 9.5 6.9 0.1 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4665) Syntaxin-6_N PF09177.11 EEQ38975.1 - 0.51 10.9 8.6 1.3 9.6 2.4 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SlyX PF04102.12 EEQ38975.1 - 0.52 11.0 3.2 1.4 9.6 0.3 2.4 2 0 0 2 2 2 0 SlyX Paralemmin PF03285.15 EEQ38975.1 - 0.59 9.7 8.2 0.96 9.0 8.2 1.4 1 1 0 1 1 1 0 Paralemmin TPR_MLP1_2 PF07926.12 EEQ38975.1 - 0.6 10.2 13.5 2.3 8.3 11.6 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4140 PF13600.6 EEQ38975.1 - 0.64 10.5 6.2 0.57 10.7 1.1 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 EEQ38975.1 - 0.65 10.7 5.6 1.8 9.2 0.2 2.4 1 1 0 2 2 2 0 Initiation control protein YabA BST2 PF16716.5 EEQ38975.1 - 0.72 10.5 5.6 0.62 10.7 0.5 2.4 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 Spc7 PF08317.11 EEQ38975.1 - 0.72 8.7 11.2 2.1 7.1 11.2 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EEQ38975.1 - 0.74 9.3 5.3 0.97 8.9 5.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit EMP24_GP25L PF01105.24 EEQ38975.1 - 0.79 9.6 8.5 0.15 12.0 0.8 2.2 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD THOC7 PF05615.13 EEQ38975.1 - 0.98 9.7 12.1 0.79 10.0 2.8 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 CENP-K PF11802.8 EEQ38975.1 - 1.1 8.8 7.9 1.7 8.1 5.5 1.8 1 1 1 2 2 2 0 Centromere-associated protein K Enkurin PF13864.6 EEQ38975.1 - 1.2 9.7 5.9 11 6.6 0.6 2.5 2 1 0 2 2 2 0 Calmodulin-binding FapA PF03961.13 EEQ38975.1 - 1.2 7.6 5.6 2 7.0 5.6 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A TMF_TATA_bd PF12325.8 EEQ38975.1 - 1.4 9.1 12.0 0.2 11.9 2.3 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EEQ38975.1 - 1.5 8.6 6.1 0.8 9.5 1.2 2.5 1 1 1 2 2 2 0 Septum formation initiator HAUS-augmin3 PF14932.6 EEQ38975.1 - 1.7 8.2 11.8 0.58 9.7 1.6 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 ATG16 PF08614.11 EEQ38975.1 - 1.7 8.9 14.1 0.23 11.6 3.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) V_ATPase_I PF01496.19 EEQ38975.1 - 1.7 6.5 5.6 3.5 5.4 5.7 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family CC2-LZ PF16516.5 EEQ38975.1 - 2.2 8.7 8.9 2.6 8.5 1.1 2.9 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator USP8_interact PF08941.10 EEQ38975.1 - 2.8 7.7 5.2 1.8 8.3 0.2 2.1 1 1 1 2 2 2 0 USP8 interacting Atg14 PF10186.9 EEQ38975.1 - 2.9 6.9 12.0 18 4.3 12.0 1.9 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TolA_bind_tri PF16331.5 EEQ38975.1 - 3.1 8.0 7.3 5.8 7.1 0.4 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation Fib_alpha PF08702.10 EEQ38975.1 - 3.3 7.9 5.6 4.3 7.5 2.2 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family HR1 PF02185.16 EEQ38975.1 - 3.3 7.9 10.7 0.47 10.6 1.5 2.6 2 1 0 2 2 2 0 Hr1 repeat YkyA PF10368.9 EEQ38975.1 - 7.8 6.1 11.6 0.63 9.7 1.9 2.2 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein APG6_N PF17675.1 EEQ38975.1 - 7.8 7.0 14.6 0.92 10.0 5.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region HIP1_clath_bdg PF16515.5 EEQ38975.1 - 8.1 7.1 12.8 17 6.1 3.1 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 L31 PF09784.9 EEQ38976.1 - 1.2e-41 141.2 2.5 1.4e-41 141.1 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 DUF1366 PF07104.11 EEQ38976.1 - 0.023 14.4 0.1 0.027 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Fanconi_C PF02106.15 EEQ38977.1 - 0.24 10.1 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group C protein Ecl1 PF12855.7 EEQ38978.1 - 9.6e-10 39.9 2.2 1.2e-09 39.5 2.2 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EEQ38978.1 - 0.077 13.1 4.0 0.13 12.4 4.0 1.4 1 0 0 1 1 1 0 MYND finger DUF3079 PF11278.8 EEQ38978.1 - 0.39 10.6 3.0 0.64 9.9 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3079) DUF3262 PF11660.8 EEQ38979.1 - 3.7 8.0 7.5 0.67 10.4 1.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3262) PWI PF01480.17 EEQ38982.1 - 9e-07 29.1 1.0 2.6e-06 27.6 0.5 2.1 2 0 0 2 2 2 1 PWI domain CsgA PF17334.2 EEQ38983.1 - 9.5 7.0 8.4 9.3 7.1 0.4 3.9 4 0 0 4 4 4 0 Minor curli fiber component A GATA PF00320.27 EEQ38984.1 - 0.094 12.3 0.3 0.2 11.3 0.3 1.6 1 0 0 1 1 1 0 GATA zinc finger C1_1 PF00130.22 EEQ38984.1 - 0.12 12.3 0.5 0.37 10.7 0.5 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_4 PF12799.7 EEQ38984.1 - 0.21 12.1 0.1 0.21 12.1 0.1 5.4 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EEQ38984.1 - 1.3 9.3 17.9 4.4 7.6 0.0 6.8 7 0 0 7 7 7 0 Leucine Rich repeat Thg1 PF04446.12 EEQ38985.1 - 2.7e-50 169.6 0.6 3.7e-50 169.1 0.6 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EEQ38985.1 - 2.9e-48 163.0 0.2 4.1e-48 162.6 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain RNA_pol_Rpb2_6 PF00562.28 EEQ38986.1 - 1.4e-112 376.6 0.0 2.6e-112 375.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EEQ38986.1 - 9.8e-39 133.0 0.0 1.4e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EEQ38986.1 - 1.5e-28 98.8 0.0 3.2e-28 97.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EEQ38986.1 - 2.5e-26 92.5 0.0 4.6e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EEQ38986.1 - 3.9e-23 81.2 0.0 8.7e-23 80.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 EEQ38986.1 - 6.2e-17 61.8 0.0 2.2e-15 56.8 0.0 2.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 ABC2_membrane PF01061.24 EEQ38987.1 - 3.9e-83 278.0 58.6 7e-44 149.8 21.1 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EEQ38987.1 - 8.7e-40 136.4 0.0 1.4e-18 67.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EEQ38987.1 - 8.5e-33 112.1 13.1 2.3e-30 104.4 0.2 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EEQ38987.1 - 4.2e-20 72.1 0.0 1.1e-19 70.8 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EEQ38987.1 - 5.5e-07 29.6 0.0 6.4e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EEQ38987.1 - 2.1e-06 27.4 0.2 0.0001 22.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EEQ38987.1 - 9.7e-06 26.2 3.0 0.17 12.3 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EEQ38987.1 - 9.1e-05 22.9 0.0 0.0035 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EEQ38987.1 - 9.6e-05 22.1 0.2 0.1 12.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EEQ38987.1 - 0.00021 20.5 40.9 0.00027 20.2 13.9 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EEQ38987.1 - 0.0014 18.5 0.1 2.2 8.0 0.2 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ38987.1 - 0.0015 18.0 0.2 0.71 9.3 0.0 3.5 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EEQ38987.1 - 0.005 16.6 0.2 0.52 10.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 EEQ38987.1 - 0.0089 16.1 0.1 0.77 9.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EEQ38987.1 - 0.012 15.6 2.0 1.3 8.9 0.1 3.2 3 0 0 3 3 3 0 NACHT domain AAA_22 PF13401.6 EEQ38987.1 - 0.013 15.7 1.1 0.4 10.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EEQ38987.1 - 0.039 14.5 0.0 1 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EEQ38987.1 - 0.05 13.8 2.1 0.12 12.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 EEQ38987.1 - 0.076 11.8 1.2 0.42 9.4 0.2 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 EEQ38987.1 - 0.081 12.5 3.3 1.4 8.5 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF2946 PF11162.8 EEQ38987.1 - 0.14 12.9 0.2 23 5.7 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) AAA_17 PF13207.6 EEQ38987.1 - 0.31 11.5 0.7 42 4.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_6 PF12774.7 EEQ38989.1 - 6.5e-107 357.3 4.1 1.4e-104 349.6 0.0 4.6 5 0 0 5 5 5 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EEQ38989.1 - 3.1e-95 319.6 16.6 3.1e-95 319.6 16.6 5.8 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EEQ38989.1 - 1.3e-52 178.2 0.1 1.3e-52 178.2 0.1 4.1 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 EEQ38989.1 - 2.9e-47 161.2 1.5 1.3e-46 159.1 0.0 3.0 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EEQ38989.1 - 1.3e-42 145.3 1.0 1.7e-36 125.4 0.0 5.0 5 0 0 5 5 5 2 P-loop containing dynein motor region DHC_N1 PF08385.12 EEQ38989.1 - 6.7e-41 140.6 22.4 6.7e-41 140.6 22.4 4.5 4 1 1 5 5 5 1 Dynein heavy chain, N-terminal region 1 MT PF12777.7 EEQ38989.1 - 3.5e-29 101.9 6.4 3.5e-29 101.9 6.4 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EEQ38989.1 - 1.8e-26 92.9 0.2 7.3e-26 90.9 0.2 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EEQ38989.1 - 1.9e-21 76.3 0.0 1.4e-19 70.3 0.1 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 EEQ38989.1 - 6.3e-21 74.8 0.0 3e-08 33.7 0.0 6.3 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EEQ38989.1 - 5.9e-16 59.1 0.0 2.2e-05 24.9 0.0 5.6 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EEQ38989.1 - 6e-11 42.8 6.5 0.00032 21.0 0.0 7.2 8 0 0 8 8 5 2 AAA domain Dynein_AAA_lid PF17852.1 EEQ38989.1 - 3.4e-09 36.9 0.2 3.4e-09 36.9 0.2 3.4 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_18 PF13238.6 EEQ38989.1 - 1.6e-08 35.1 0.0 1.1 9.8 0.0 5.3 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 EEQ38989.1 - 7.9e-08 31.7 0.0 0.29 10.2 0.0 3.6 3 0 0 3 3 3 3 Type II/IV secretion system protein AAA_33 PF13671.6 EEQ38989.1 - 2.1e-07 31.2 0.7 0.28 11.3 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_lid_1 PF17857.1 EEQ38989.1 - 1.2e-05 25.4 0.1 0.00099 19.3 0.0 3.8 3 0 0 3 3 3 1 AAA+ lid domain AAA_29 PF13555.6 EEQ38989.1 - 2.1e-05 24.2 0.3 0.86 9.4 0.0 3.8 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ38989.1 - 3.7e-05 24.2 1.7 4.3 7.7 0.0 6.2 7 0 0 7 7 7 1 AAA ATPase domain AAA_25 PF13481.6 EEQ38989.1 - 4.2e-05 23.2 0.0 0.0043 16.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEQ38989.1 - 0.0013 18.5 0.4 4 7.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 EEQ38989.1 - 0.0021 17.8 0.1 0.73 9.5 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEQ38989.1 - 0.0026 17.2 1.9 1.6 8.1 0.0 3.7 4 0 0 4 4 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EEQ38989.1 - 0.0039 16.9 0.1 15 5.2 0.0 4.5 5 0 0 5 5 5 0 AAA domain BRE1 PF08647.11 EEQ38989.1 - 0.0052 16.8 8.1 0.0068 16.5 4.6 3.3 2 0 0 2 2 1 1 BRE1 E3 ubiquitin ligase RuvB_N PF05496.12 EEQ38989.1 - 0.02 14.6 0.1 0.47 10.2 0.0 2.8 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_lid_7 PF17867.1 EEQ38989.1 - 0.029 14.6 4.4 0.23 11.7 0.1 4.3 4 0 0 4 4 4 0 Midasin AAA lid domain FtsK_SpoIIIE PF01580.18 EEQ38989.1 - 0.058 12.7 0.1 36 3.6 0.0 3.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EEQ38989.1 - 0.078 13.5 8.6 14 6.2 0.0 5.2 5 0 0 5 5 3 0 ABC transporter cobW PF02492.19 EEQ38989.1 - 0.18 11.4 1.5 1.9 8.0 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EEQ38989.1 - 0.18 11.5 3.1 18 5.1 0.1 3.8 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 EEQ38989.1 - 0.19 12.1 4.9 2.2 8.6 0.0 4.4 5 0 0 5 5 4 0 AAA domain DUF4446 PF14584.6 EEQ38989.1 - 1.6 8.7 11.0 19 5.2 1.3 4.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) ZapB PF06005.12 EEQ38989.1 - 3.5 8.1 15.1 1.5 9.3 7.1 4.2 2 1 1 3 3 3 0 Cell division protein ZapB Ribosomal_S19e PF01090.19 EEQ38990.1 - 1e-44 151.6 0.0 1.2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box-like PF12937.7 EEQ38991.1 - 0.0097 15.8 0.5 0.032 14.1 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ38991.1 - 0.18 11.7 6.2 0.99 9.4 0.9 3.3 3 0 0 3 3 3 0 F-box domain Med18 PF09637.10 EEQ38993.1 - 1.5e-89 300.1 0.4 1.7e-89 300.0 0.4 1.0 1 0 0 1 1 1 1 Med18 protein VMA21 PF09446.10 EEQ38994.1 - 1.3e-06 28.4 17.7 7.7e-06 25.9 17.7 1.8 1 1 0 1 1 1 1 VMA21-like domain KdgT PF03812.13 EEQ38994.1 - 0.027 13.8 0.9 0.028 13.7 0.9 1.0 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease 7TM_GPCR_Srb PF02175.16 EEQ38994.1 - 0.06 13.1 0.6 0.066 13.0 0.6 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srb Sensor_TM1 PF13755.6 EEQ38994.1 - 0.095 12.5 0.7 0.11 12.2 0.7 1.1 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain ATP-synt_S1 PF05827.12 EEQ38995.1 - 3.4e-05 23.7 0.0 6.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) RPN2_C PF18004.1 EEQ38995.1 - 0.11 12.4 0.6 1.7 8.5 0.0 2.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain ERG4_ERG24 PF01222.17 EEQ38996.1 - 1.3e-149 498.6 14.1 1.5e-149 498.4 14.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EEQ38996.1 - 1.4e-07 31.2 1.9 3.9e-07 29.8 1.7 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) LegC3_N PF18654.1 EEQ38997.1 - 0.11 11.7 0.7 0.19 11.0 0.7 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain NmrA PF05368.13 EEQ38998.1 - 1.4e-05 24.8 0.7 2e-05 24.3 0.7 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EEQ38998.1 - 0.0024 17.8 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EEQ38998.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_L3 PF00297.22 EEQ38999.1 - 3.4e-186 618.6 10.4 3.8e-186 618.4 10.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PHD PF00628.29 EEQ39000.1 - 8.6e-05 22.3 7.3 0.0002 21.2 7.3 1.7 1 0 0 1 1 1 1 PHD-finger DUF848 PF05852.11 EEQ39000.1 - 0.0027 17.8 3.5 0.0053 16.9 3.5 1.5 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) zf-HC5HC2H PF13771.6 EEQ39000.1 - 0.011 16.0 2.2 0.011 16.0 2.2 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Phage_Mu_Gam PF07352.12 EEQ39000.1 - 0.013 15.4 2.0 0.031 14.2 2.0 1.7 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Cob_adeno_trans PF01923.18 EEQ39000.1 - 0.054 13.6 0.6 0.084 13.0 0.6 1.4 1 0 0 1 1 1 0 Cobalamin adenosyltransferase DUF2116 PF09889.9 EEQ39000.1 - 0.085 12.8 7.1 0.062 13.3 4.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) GIT_CC PF16559.5 EEQ39000.1 - 0.22 11.4 3.4 0.34 10.8 1.9 2.0 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor zf-HC5HC2H_2 PF13832.6 EEQ39000.1 - 0.5 10.5 5.2 0.14 12.3 1.5 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain Lge1 PF11488.8 EEQ39000.1 - 0.51 10.5 7.0 2.1 8.6 5.0 3.0 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 zf-4CXXC_R1 PF10497.9 EEQ39000.1 - 0.59 10.4 8.1 1.5 9.1 8.1 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FOXP-CC PF16159.5 EEQ39000.1 - 8.9 7.0 8.8 15 6.3 0.0 3.6 3 0 0 3 3 3 0 FOXP coiled-coil domain UTP15_C PF09384.10 EEQ39001.1 - 2.5e-44 150.5 0.1 3.5e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EEQ39001.1 - 9.3e-10 39.0 2.4 0.31 12.0 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39001.1 - 4.8e-07 30.0 0.0 0.13 12.5 0.0 4.2 3 3 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain STAG PF08514.11 EEQ39001.1 - 0.064 13.2 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 STAG domain dUTPase PF00692.19 EEQ39003.1 - 8e-46 154.9 0.0 9.3e-46 154.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase LETM1 PF07766.13 EEQ39004.1 - 6.6e-99 330.6 1.4 6.6e-99 330.6 1.4 1.9 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 EEQ39004.1 - 0.0026 17.5 0.0 0.0066 16.2 0.0 1.7 1 0 0 1 1 1 1 SAP domain PITH PF06201.13 EEQ39005.1 - 6.6e-25 88.1 0.0 1.2e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EEQ39005.1 - 1.5e-20 73.1 0.1 2.7e-20 72.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EEQ39005.1 - 2.9e-05 24.1 0.1 6.3e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EEQ39005.1 - 5.4e-05 23.4 0.2 0.00046 20.5 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EEQ39005.1 - 6.4e-05 23.4 1.1 0.00018 21.9 0.2 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EEQ39005.1 - 0.01 15.6 0.1 0.031 14.1 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin OST3_OST6 PF04756.13 EEQ39005.1 - 0.03 13.7 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EEQ39005.1 - 0.045 13.7 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Med22 PF06179.12 EEQ39007.1 - 1e-10 41.8 0.3 1.1e-10 41.6 0.3 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Sedlin_N PF04628.13 EEQ39010.1 - 2.1e-44 150.8 0.0 2.5e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EEQ39010.1 - 0.00025 21.0 0.8 0.0012 18.8 0.4 2.3 2 1 0 2 2 2 1 Sybindin-like family Fructosamin_kin PF03881.14 EEQ39011.1 - 0.0057 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase Kdo PF06293.14 EEQ39011.1 - 0.056 12.8 0.0 0.31 10.3 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_HK97_TLTM PF06120.11 EEQ39011.1 - 0.12 11.5 0.3 0.29 10.3 0.3 1.6 1 0 0 1 1 1 0 Tail length tape measure protein FMO-like PF00743.19 EEQ39013.1 - 5.1e-41 140.7 0.2 8.2e-20 70.7 0.2 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EEQ39013.1 - 2.7e-18 66.3 2.3 1.2e-13 51.0 0.7 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ39013.1 - 1.3e-13 50.9 0.0 4.1e-13 49.2 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EEQ39013.1 - 2.4e-10 40.6 0.4 4e-09 36.6 0.1 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EEQ39013.1 - 8.8e-08 32.3 0.0 2.5e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EEQ39013.1 - 1.5e-07 30.9 0.8 0.00014 21.2 0.5 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EEQ39013.1 - 2.4e-07 30.7 0.0 0.039 13.5 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEQ39013.1 - 2.4e-05 24.8 0.1 2.4 8.8 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EEQ39013.1 - 7.8e-05 22.1 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Thi4 PF01946.17 EEQ39013.1 - 0.00027 20.3 0.3 0.0032 16.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EEQ39013.1 - 0.00069 18.4 0.3 0.076 11.7 0.1 2.7 3 0 0 3 3 3 1 HI0933-like protein DUF1188 PF06690.11 EEQ39013.1 - 0.0035 16.9 0.4 0.0035 16.9 0.4 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1188) FAD_binding_3 PF01494.19 EEQ39013.1 - 0.02 14.1 0.0 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 EEQ39013.1 - 0.034 13.0 0.1 0.79 8.5 0.0 2.6 2 1 1 3 3 3 0 Tryptophan halogenase Catalase_C PF18011.1 EEQ39013.1 - 0.051 13.2 0.2 0.094 12.4 0.2 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases Mqo PF06039.15 EEQ39013.1 - 0.074 11.6 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 EEQ39013.1 - 0.08 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EEQ39013.1 - 0.14 12.6 0.1 28 5.2 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EEQ39013.1 - 0.14 11.1 0.0 0.69 8.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Arf PF00025.21 EEQ39014.1 - 4.4e-48 163.0 0.0 4.9e-48 162.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EEQ39014.1 - 1.3e-07 31.2 0.0 2.9e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 EEQ39014.1 - 0.00038 20.1 0.0 0.00046 19.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EEQ39014.1 - 0.00082 18.8 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EEQ39014.1 - 0.0012 19.1 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EEQ39014.1 - 0.0079 15.7 0.0 0.0083 15.7 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEQ39014.1 - 0.09 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase MMR_HSR1 PF01926.23 EEQ39015.1 - 1e-15 57.8 0.1 1e-13 51.3 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ39015.1 - 1.9e-06 27.5 0.1 4.5e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEQ39015.1 - 0.00011 22.2 0.4 0.04 13.8 0.1 2.5 1 1 1 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EEQ39015.1 - 0.011 15.8 0.1 0.054 13.6 0.1 2.3 1 0 0 1 1 1 0 Dynamin family AIG1 PF04548.16 EEQ39015.1 - 0.014 14.7 0.0 0.035 13.4 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Arf PF00025.21 EEQ39015.1 - 0.06 12.8 1.8 0.83 9.1 0.8 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 EEQ39015.1 - 0.14 11.7 0.1 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MAP65_ASE1 PF03999.12 EEQ39016.1 - 1.8e-52 178.9 24.7 2.6e-52 178.4 24.7 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) FtsQ PF03799.15 EEQ39016.1 - 0.11 13.3 0.1 0.43 11.4 0.1 2.0 2 0 0 2 2 2 0 Cell division protein FtsQ WTF PF03303.13 EEQ39016.1 - 0.8 9.4 5.2 4.2 7.0 0.3 2.4 2 0 0 2 2 2 0 WTF protein ATP-synt_B PF00430.18 EEQ39016.1 - 2.3 8.3 4.8 3.1 7.9 1.4 2.5 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) RPAP3_C PF13877.6 EEQ39018.1 - 0.013 16.0 0.6 14 6.3 0.1 3.8 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 PQ-loop PF04193.14 EEQ39019.1 - 1.2e-35 121.0 15.4 1.6e-19 69.4 3.6 2.7 3 0 0 3 3 3 2 PQ loop repeat MtN3_slv PF03083.16 EEQ39019.1 - 0.54 10.3 8.4 0.54 10.3 0.1 2.4 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Pyridoxal_deC PF00282.19 EEQ39020.1 - 1.8e-19 69.7 0.0 2.6e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EEQ39020.1 - 2.3e-07 30.1 0.0 4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ39020.1 - 1.3e-05 24.7 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EEQ39020.1 - 0.054 12.0 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3709 PF12493.8 EEQ39020.1 - 8.8 6.5 9.9 17 5.5 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3709) HDA2-3 PF11496.8 EEQ39021.1 - 1.4e-40 139.3 0.0 3.9e-40 137.9 0.0 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 MscS_porin PF12795.7 EEQ39021.1 - 0.48 9.9 20.5 0.11 12.1 8.9 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain Cep57_MT_bd PF06657.13 EEQ39021.1 - 7.2 7.1 10.9 0.087 13.3 1.5 2.7 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 EF-hand_4 PF12763.7 EEQ39022.1 - 2.5e-05 24.2 0.0 5.3e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EEQ39022.1 - 0.093 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EEQ39022.1 - 0.15 12.6 0.0 0.39 11.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair PIN_6 PF17146.4 EEQ39023.1 - 2.7e-30 104.7 0.2 8.9e-30 103.0 0.0 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EEQ39023.1 - 1.2e-24 86.3 0.9 2.8e-24 85.1 0.9 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Zn-ribbon_8 PF09723.10 EEQ39023.1 - 0.22 11.7 6.9 0.073 13.2 2.9 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Nop25 PF09805.9 EEQ39023.1 - 0.32 11.4 26.7 0.099 13.1 19.1 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) FAM60A PF15396.6 EEQ39023.1 - 7.5 6.5 15.9 5.1 7.0 9.7 2.4 2 0 0 2 2 2 0 Protein Family FAM60A NPR3 PF03666.13 EEQ39023.1 - 8 5.1 19.4 0.11 11.3 11.2 1.9 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 GST_C_3 PF14497.6 EEQ39024.1 - 6.8e-09 35.8 0.0 7.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EEQ39024.1 - 2.9e-07 30.6 0.0 3.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ39024.1 - 2.5e-06 27.4 0.0 5.2e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PUF PF00806.19 EEQ39025.1 - 1.5e-23 81.0 1.3 0.0001 21.8 0.0 8.3 9 0 0 9 9 9 5 Pumilio-family RNA binding repeat eIF3_p135 PF12807.7 EEQ39025.1 - 0.0022 18.1 0.6 0.0083 16.2 0.6 2.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 IL3 PF02059.15 EEQ39025.1 - 0.38 10.8 2.9 18 5.4 0.2 3.6 4 0 0 4 4 4 0 Interleukin-3 tRNA-synt_2 PF00152.20 EEQ39026.1 - 7.9e-102 340.5 0.0 9.5e-102 340.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ39026.1 - 8.9e-08 32.0 0.0 2.5e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEQ39026.1 - 0.0099 15.4 0.1 0.028 13.9 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 EEQ39026.1 - 0.023 14.7 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Glyco_transf_15 PF01793.16 EEQ39027.1 - 1.7e-116 389.0 15.7 5.8e-116 387.3 12.8 2.0 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase TauD PF02668.16 EEQ39028.1 - 1.3e-54 185.9 0.2 1.6e-54 185.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GST_N PF02798.20 EEQ39029.1 - 6e-12 45.7 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEQ39029.1 - 1.1e-10 41.7 0.0 1.9e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ39029.1 - 2.7e-08 34.1 0.0 5.4e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEQ39029.1 - 5.5e-06 26.5 0.0 9.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EEQ39029.1 - 0.0024 18.1 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ39029.1 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Amidase PF01425.21 EEQ39030.1 - 6.2e-93 312.2 0.0 1.4e-92 311.1 0.0 1.5 1 1 0 1 1 1 1 Amidase UPF0180 PF03698.13 EEQ39030.1 - 0.041 14.1 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) SSF PF00474.17 EEQ39031.1 - 6.3e-14 51.7 19.6 6.3e-14 51.7 19.6 2.0 2 0 0 2 2 2 1 Sodium:solute symporter family PPTA PF01239.22 EEQ39032.1 - 2.7e-28 96.8 6.3 1.5e-08 34.1 0.0 3.6 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat Syntaxin-6_N PF09177.11 EEQ39032.1 - 0.032 14.8 0.4 0.053 14.1 0.4 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Luteo_Vpg PF01659.16 EEQ39032.1 - 0.077 13.3 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein DUF3950 PF13132.6 EEQ39032.1 - 0.33 10.7 2.8 0.82 9.5 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) CtaG_Cox11 PF04442.14 EEQ39033.1 - 6.7e-57 191.8 0.1 9.5e-57 191.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Cupredoxin_1 PF13473.6 EEQ39033.1 - 0.0095 16.0 0.0 0.69 10.0 0.0 2.2 2 0 0 2 2 2 2 Cupredoxin-like domain IBN_N PF03810.19 EEQ39034.1 - 8.5e-17 60.8 1.9 9.2e-16 57.5 0.2 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EEQ39034.1 - 0.0012 19.0 0.5 0.019 15.0 0.1 3.2 2 0 0 2 2 2 1 Exportin 1-like protein HLH PF00010.26 EEQ39034.1 - 0.07 13.1 1.3 0.37 10.8 0.0 2.8 3 0 0 3 3 3 0 Helix-loop-helix DNA-binding domain NAPRTase PF04095.16 EEQ39035.1 - 4.2e-43 147.7 0.0 6e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EEQ39035.1 - 3e-36 124.6 0.9 4.4e-36 124.0 0.1 1.7 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain UDPGP PF01704.18 EEQ39036.1 - 3e-191 635.5 0.0 3.4e-191 635.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Mannosyl_trans3 PF11051.8 EEQ39037.1 - 3.3e-42 144.7 0.0 4.6e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative RNA_pol_Rpb8 PF03870.15 EEQ39038.1 - 2.3e-45 154.2 0.1 2.6e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EEQ39038.1 - 3.4e-08 33.5 0.8 0.0045 17.0 0.2 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G DUF3464 PF11947.8 EEQ39039.1 - 0.00022 21.0 2.1 0.07 12.9 1.0 2.2 2 0 0 2 2 2 2 Photosynthesis affected mutant 68 Cation_ATPase_C PF00689.21 EEQ39039.1 - 0.002 17.9 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Orf78 PF06024.12 EEQ39039.1 - 0.0021 18.3 1.1 0.0064 16.8 0.3 1.9 2 0 0 2 2 2 1 Orf78 (ac78) LRRC37AB_C PF14914.6 EEQ39039.1 - 0.0022 17.9 0.7 0.0036 17.2 0.7 1.3 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain PBP1_TM PF14812.6 EEQ39039.1 - 0.0061 16.9 10.1 0.0061 16.9 10.1 1.9 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_E56 PF04639.12 EEQ39039.1 - 0.0083 15.4 0.3 0.037 13.3 0.0 1.8 2 0 0 2 2 2 1 Baculoviral E56 protein, specific to ODV envelope CSG2 PF16965.5 EEQ39039.1 - 0.011 14.7 0.0 0.013 14.4 0.0 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DNA_pol_phi PF04931.13 EEQ39039.1 - 0.013 13.6 8.5 0.007 14.5 5.5 1.8 2 0 0 2 2 2 0 DNA polymerase phi RXT2_N PF08595.11 EEQ39039.1 - 0.022 14.8 8.1 0.039 14.0 8.1 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal OATP PF03137.20 EEQ39039.1 - 0.023 13.0 0.0 0.03 12.6 0.0 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Connexin PF00029.19 EEQ39039.1 - 0.032 14.0 0.1 0.036 13.8 0.1 1.3 1 0 0 1 1 1 0 Connexin GWT1 PF06423.12 EEQ39039.1 - 0.074 13.2 0.5 0.53 10.4 0.0 1.9 1 1 0 2 2 2 0 GWT1 Shisa PF13908.6 EEQ39039.1 - 0.093 13.0 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RRN3 PF05327.11 EEQ39039.1 - 0.11 11.1 4.6 0.12 10.9 4.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2457 PF10446.9 EEQ39039.1 - 0.11 11.6 16.5 0.15 11.2 16.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.16 EEQ39039.1 - 0.15 11.2 3.2 0.2 10.9 3.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 EEQ39039.1 - 0.18 12.2 3.1 0.24 11.8 3.1 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF3899 PF13038.6 EEQ39039.1 - 0.22 12.0 14.2 59 4.3 10.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) Tom6 PF17112.5 EEQ39039.1 - 0.24 10.9 0.1 0.24 10.9 0.1 1.6 2 0 0 2 2 1 0 Mitochondrial import receptor subunit Tom6, fungal Zip PF02535.22 EEQ39039.1 - 0.37 10.0 3.0 0.54 9.4 3.0 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Ferlin_C PF16165.5 EEQ39039.1 - 0.44 10.5 7.4 0.14 12.0 4.2 1.9 2 0 0 2 2 2 0 Ferlin C-terminus DUF2796 PF10986.8 EEQ39039.1 - 1 9.3 7.5 1.4 8.8 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) CDC45 PF02724.14 EEQ39039.1 - 1.9 6.7 12.9 2.5 6.3 12.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 EEQ39039.1 - 2.6 7.3 15.3 3.3 6.9 15.3 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.8 EEQ39039.1 - 3.9 6.3 9.4 5.1 5.9 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RPN2_C PF18004.1 EEQ39039.1 - 4.8 7.1 13.2 6.7 6.6 13.2 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain MFS_1 PF07690.16 EEQ39040.1 - 1.7e-06 27.2 45.7 0.00015 20.8 26.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Na_trans_cytopl PF11933.8 EEQ39040.1 - 0.0037 17.1 0.0 0.006 16.4 0.0 1.2 1 0 0 1 1 1 1 Cytoplasmic domain of voltage-gated Na+ ion channel DUF2462 PF09495.10 EEQ39041.1 - 4.1e-16 59.5 6.8 4.1e-16 59.5 6.8 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) GATase_5 PF13507.6 EEQ39042.1 - 5.6e-102 340.3 0.0 8.6e-102 339.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EEQ39042.1 - 1.4e-38 132.5 1.1 1.9e-27 96.3 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EEQ39042.1 - 2.6e-26 91.9 0.0 5e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EEQ39042.1 - 2.1e-21 76.2 0.0 5.5e-21 74.9 0.0 1.8 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain Ribosomal_S3_C PF00189.20 EEQ39043.1 - 9.1e-23 80.6 1.7 2.5e-22 79.2 0.6 2.2 2 1 1 3 3 3 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EEQ39043.1 - 3.4e-09 36.4 0.6 7.6e-09 35.3 0.6 1.6 1 0 0 1 1 1 1 KH domain Tmemb_14 PF03647.13 EEQ39045.1 - 4.1e-25 88.3 4.0 4.6e-25 88.2 4.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 EEQ39045.1 - 8.9e-05 22.8 2.3 0.00025 21.3 2.3 1.7 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF998 PF06197.13 EEQ39045.1 - 0.12 11.9 2.4 2 8.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF998) SNF2_N PF00176.23 EEQ39046.1 - 2e-65 220.8 0.6 3.6e-65 220.0 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 EEQ39046.1 - 3.7e-48 163.3 22.2 3.7e-48 163.3 22.2 2.3 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.31 EEQ39046.1 - 1.3e-17 64.2 0.0 5.3e-17 62.2 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EEQ39046.1 - 2.4e-06 26.9 0.2 2.4e-06 26.9 0.2 3.5 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EEQ39046.1 - 5.5e-06 26.5 3.2 3.3e-05 24.0 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Fe_hyd_lg_C PF02906.14 EEQ39046.1 - 0.0024 17.6 0.3 0.0058 16.3 0.3 1.6 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Vezatin PF12632.7 EEQ39047.1 - 5.9e-54 183.3 12.6 1.9e-53 181.6 12.6 1.9 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes Fungal_trans PF04082.18 EEQ39048.1 - 9e-24 83.9 0.1 1.9e-23 82.8 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ39048.1 - 1.5e-06 28.2 14.3 2.8e-06 27.4 14.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C14 PF00656.22 EEQ39050.1 - 6.5e-64 216.3 0.0 9.2e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Caspase domain adh_short_C2 PF13561.6 EEQ39051.1 - 9.9e-42 143.1 0.6 1.2e-41 142.8 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ39051.1 - 5e-35 120.7 0.9 7e-35 120.3 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ39051.1 - 1.9e-08 34.4 1.4 2.7e-08 33.9 1.4 1.2 1 0 0 1 1 1 1 KR domain DUF1977 PF09320.11 EEQ39052.1 - 2.5e-34 117.7 1.3 5.4e-34 116.6 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EEQ39052.1 - 2.5e-23 82.0 0.3 4.2e-23 81.3 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Asp PF00026.23 EEQ39053.1 - 8e-65 219.3 14.8 5e-56 190.4 7.9 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ39053.1 - 2e-09 37.9 2.9 0.0015 18.8 1.2 2.7 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 EEQ39053.1 - 6.6e-05 23.4 0.0 0.71 10.5 0.0 3.9 4 0 0 4 4 4 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EEQ39053.1 - 0.00017 22.2 0.1 1.9 9.2 0.0 3.5 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.6 EEQ39053.1 - 0.00051 19.9 0.1 0.0051 16.6 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF5443 PF17518.2 EEQ39053.1 - 0.069 12.1 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5443) HAMP PF00672.25 EEQ39054.1 - 4.3e-34 116.7 13.1 4e-09 36.7 1.0 6.4 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 EEQ39054.1 - 7.5e-31 106.9 0.2 1.7e-30 105.8 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EEQ39054.1 - 8.4e-26 90.3 0.5 4.9e-25 87.9 0.2 2.6 2 1 1 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 EEQ39054.1 - 1.5e-17 63.4 1.4 1.4e-16 60.3 0.6 3.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF4279 PF14106.6 EEQ39054.1 - 0.015 15.5 0.3 4.5 7.5 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4279) Terpene_synth_C PF03936.16 EEQ39054.1 - 0.042 13.2 0.5 0.21 10.9 0.1 2.3 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain IL32 PF15225.6 EEQ39054.1 - 0.11 12.9 0.2 71 3.8 0.0 4.0 4 0 0 4 4 4 0 Interleukin 32 PseudoU_synth_1 PF01416.20 EEQ39054.1 - 0.29 11.6 0.8 69 4.0 0.0 4.0 4 0 0 4 4 4 0 tRNA pseudouridine synthase Phage_holin_6_1 PF09682.10 EEQ39054.1 - 0.32 11.4 5.8 0.72 10.3 0.7 3.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) CENP-F_leu_zip PF10473.9 EEQ39054.1 - 0.9 9.6 8.8 25 4.9 0.0 5.3 5 0 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF421 PF04239.12 EEQ39054.1 - 1.6 8.5 5.9 1.5 8.6 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF421) DUF3829 PF12889.7 EEQ39054.1 - 3.2 7.1 16.2 1.3 8.4 0.8 5.1 5 1 0 5 5 5 0 Protein of unknown function (DUF3829) DNA_pol_B PF00136.21 EEQ39055.1 - 8.1e-74 249.0 5.8 1e-73 248.7 5.8 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-C4pol PF14260.6 EEQ39055.1 - 5.6e-19 68.4 9.4 1.4e-18 67.1 9.4 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta C1_1 PF00130.22 EEQ39055.1 - 0.6 10.0 10.7 1.7 8.6 1.3 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 EEQ39055.1 - 5.3 7.1 11.9 5.4e+02 0.7 11.9 2.5 1 1 0 1 1 1 0 zinc-ribbons DZR PF12773.7 EEQ39055.1 - 7.8 6.6 13.4 43 4.3 11.8 2.5 2 1 0 2 2 2 0 Double zinc ribbon DNA_pol_B_exo1 PF03104.19 EEQ39056.1 - 8.6e-85 284.8 0.2 1.2e-84 284.4 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EEQ39056.1 - 1.8e-32 112.7 0.1 2.8e-32 112.1 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B RNase_H_2 PF13482.6 EEQ39056.1 - 0.0079 16.2 0.1 0.079 12.9 0.1 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 EEQ39056.1 - 0.0083 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.13 EEQ39056.1 - 0.011 14.6 0.1 0.03 13.2 0.0 1.6 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral CBM_17_28 PF03424.14 EEQ39056.1 - 0.056 13.1 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 17/28) AA_permease_2 PF13520.6 EEQ39057.1 - 3.2e-32 111.9 16.8 3.9e-32 111.6 16.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ39057.1 - 1e-12 47.5 16.8 1.2e-12 47.2 16.8 1.0 1 0 0 1 1 1 1 Amino acid permease Shisa PF13908.6 EEQ39057.1 - 5.3 7.2 7.3 8.4 6.6 3.4 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator AA_permease_2 PF13520.6 EEQ39058.1 - 1e-08 34.5 15.4 1.2e-08 34.2 15.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ39059.1 - 1.3e-65 222.0 47.7 1.5e-65 221.7 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ39059.1 - 6e-18 64.7 41.6 8.5e-18 64.2 41.6 1.1 1 0 0 1 1 1 1 Amino acid permease Med5 PF08689.10 EEQ39060.1 - 0.00024 19.1 0.4 0.073 10.9 0.1 2.0 2 0 0 2 2 2 2 Mediator complex subunit Med5 Med5 PF08689.10 EEQ39061.1 - 2.1e-45 155.1 24.0 1.9e-44 151.9 24.0 1.9 1 1 0 1 1 1 1 Mediator complex subunit Med5 Pex14_N PF04695.13 EEQ39062.1 - 1.8e-37 129.4 10.6 2.4e-37 129.0 0.6 2.7 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region AbiH PF14253.6 EEQ39062.1 - 0.031 14.2 0.2 0.039 13.8 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Cnn_1N PF07989.11 EEQ39062.1 - 0.037 14.2 2.7 0.037 14.2 2.7 3.2 4 0 0 4 4 4 0 Centrosomin N-terminal motif 1 Baculo_PEP_C PF04513.12 EEQ39062.1 - 0.037 14.1 2.6 0.07 13.2 2.6 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-C4H2 PF10146.9 EEQ39062.1 - 0.26 11.6 16.2 0.56 10.5 12.4 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein TMEM52 PF14979.6 EEQ39062.1 - 0.3 11.0 1.3 3.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Transmembrane 52 Mito_carr PF00153.27 EEQ39063.1 - 6.9e-46 154.1 4.4 2.9e-16 59.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Prenyltrans PF00432.21 EEQ39064.1 - 1.2e-24 85.7 0.3 1e-05 25.1 0.0 6.0 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat ACPS PF01648.20 EEQ39065.1 - 8.3e-11 42.0 0.0 2e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Aldedh PF00171.22 EEQ39066.1 - 9.6e-180 598.0 0.7 1.1e-179 597.8 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family F-box-like PF12937.7 EEQ39067.1 - 2.1e-08 33.9 0.8 5.2e-08 32.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEQ39067.1 - 5.9e-06 26.0 0.0 2.7e-05 23.9 0.0 2.3 1 1 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EEQ39067.1 - 6.4e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 F-box ADH_N PF08240.12 EEQ39070.1 - 2.1e-23 82.3 3.3 3.5e-23 81.6 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ39070.1 - 2.3e-21 76.1 0.0 6.4e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ39070.1 - 8.6e-08 33.3 0.0 1.7e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EEQ39070.1 - 1.4e-06 27.8 0.1 2.2e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EEQ39070.1 - 3.6e-05 23.2 0.1 5.7e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Phospholip_A2_2 PF05826.12 EEQ39070.1 - 0.013 15.7 0.2 0.03 14.5 0.2 1.6 1 0 0 1 1 1 0 Phospholipase A2 NAD_binding_7 PF13241.6 EEQ39070.1 - 0.022 15.2 0.0 0.043 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 EEQ39070.1 - 0.026 15.3 0.0 0.056 14.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EEQ39070.1 - 0.031 14.5 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EEQ39070.1 - 0.033 14.2 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF364 PF04016.12 EEQ39070.1 - 0.036 13.7 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation NAD_binding_2 PF03446.15 EEQ39070.1 - 0.037 14.2 0.1 0.076 13.2 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_25 PF13649.6 EEQ39070.1 - 0.063 14.0 0.1 19 6.0 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain ELFV_dehydrog PF00208.21 EEQ39070.1 - 0.089 12.5 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Gp_dh_N PF00044.24 EEQ39070.1 - 0.11 12.9 0.1 1.1 9.7 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EEQ39070.1 - 0.12 12.9 0.3 0.23 12.1 0.3 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EEQ39070.1 - 0.23 11.3 0.3 0.39 10.6 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.12 EEQ39071.1 - 3.2e-22 78.5 5.1 5.2e-22 77.8 5.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ39071.1 - 4.6e-21 75.1 0.0 3.3e-20 72.4 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ39071.1 - 1.1e-06 29.7 0.0 1.9e-06 29.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EEQ39071.1 - 3e-06 26.7 0.1 5.1e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EEQ39071.1 - 8.9e-06 25.1 0.1 1.4e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 EEQ39071.1 - 0.029 14.6 0.1 0.052 13.8 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 EEQ39071.1 - 0.038 14.2 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EEQ39071.1 - 0.081 12.8 0.3 0.2 11.5 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EEQ39071.1 - 0.11 13.4 0.0 0.21 12.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.6 EEQ39071.1 - 0.12 12.9 0.1 0.25 11.8 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Abhydrolase_1 PF00561.20 EEQ39074.1 - 4e-10 39.8 0.0 5.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ39074.1 - 5.3e-08 32.4 0.0 2.4e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ39074.1 - 0.0017 19.0 0.0 0.0034 18.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EEQ39074.1 - 0.018 14.9 0.0 0.12 12.2 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Cutinase PF01083.22 EEQ39074.1 - 0.048 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase Pkinase PF00069.25 EEQ39075.1 - 1.2e-33 116.6 0.1 2.3e-27 96.0 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39075.1 - 1.9e-15 56.9 0.1 1.5e-09 37.5 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ39075.1 - 0.0018 17.7 0.0 0.36 10.1 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EEQ39075.1 - 0.063 13.2 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Cript PF10235.9 EEQ39076.1 - 0.065 13.8 0.3 0.1 13.1 0.3 1.3 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT DZR PF12773.7 EEQ39076.1 - 0.14 12.2 2.9 0.25 11.4 2.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-LITAF-like PF10601.9 EEQ39076.1 - 0.14 12.4 0.6 0.14 12.4 0.6 2.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain TackOD1 PF18551.1 EEQ39076.1 - 0.56 9.9 3.5 0.81 9.3 3.5 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 EAF PF09816.9 EEQ39079.1 - 6e-13 49.1 0.0 1.2e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor SNase PF00565.17 EEQ39080.1 - 2.4e-23 82.6 0.0 3.4e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PGM_PMM_I PF02878.16 EEQ39081.1 - 9.2e-18 64.3 0.2 2.1e-08 34.0 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EEQ39081.1 - 7.4e-12 45.3 0.2 2.1e-11 43.8 0.2 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.16 EEQ39081.1 - 6.1e-05 23.6 1.7 0.02 15.5 0.3 3.0 2 1 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EEQ39081.1 - 0.012 15.7 0.3 0.031 14.4 0.3 1.8 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III CinA_KH PF18146.1 EEQ39081.1 - 0.017 15.2 0.5 1.6 9.0 0.1 2.9 2 0 0 2 2 2 0 Damage-inducible protein CinA KH domain Homoserine_dh PF00742.19 EEQ39081.1 - 0.058 13.3 0.3 0.45 10.4 0.1 2.2 2 0 0 2 2 2 0 Homoserine dehydrogenase Miff PF05644.11 EEQ39081.1 - 0.067 12.8 0.2 0.55 9.8 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff KAR9 PF08580.10 EEQ39084.1 - 7.2e-19 67.8 0.0 3.6e-18 65.5 0.0 2.2 1 1 0 1 1 1 1 Yeast cortical protein KAR9 Flt3_lig PF02947.14 EEQ39085.1 - 0.016 15.4 0.1 0.034 14.3 0.1 1.5 1 1 0 1 1 1 0 flt3 ligand RrnaAD PF00398.20 EEQ39089.1 - 1.6e-71 240.5 0.1 1.9e-71 240.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EEQ39089.1 - 5.2e-08 33.5 0.0 6.9e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ39089.1 - 5.8e-06 26.9 0.0 4e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EEQ39089.1 - 0.00042 20.1 0.0 0.00061 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EEQ39089.1 - 0.00062 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EEQ39089.1 - 0.001 19.7 0.0 0.0031 18.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ39089.1 - 0.0059 16.4 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EEQ39089.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_28 PF02636.17 EEQ39089.1 - 0.016 14.9 0.1 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 EEQ39089.1 - 0.022 14.3 0.2 0.053 13.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EEQ39089.1 - 0.028 13.7 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AAA_lid_4 PF17864.1 EEQ39089.1 - 0.075 12.8 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 RuvB AAA lid domain Methyltransf_2 PF00891.18 EEQ39089.1 - 0.12 11.7 0.1 0.23 10.7 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase domain Nucleos_tra2_N PF01773.20 EEQ39090.1 - 0.0015 19.1 2.4 0.0015 19.0 0.4 2.0 1 1 1 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Kelch_4 PF13418.6 EEQ39092.1 - 1.1e-42 143.8 0.2 2.2e-08 34.0 0.1 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EEQ39092.1 - 4.1e-32 109.8 3.7 5.6e-10 39.3 0.0 6.8 7 1 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.6 EEQ39092.1 - 1e-24 86.4 0.1 1e-24 86.4 0.1 4.7 4 2 0 4 4 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 EEQ39092.1 - 1e-22 79.6 3.7 1.7e-05 24.9 0.1 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EEQ39092.1 - 1.1e-22 79.6 1.1 0.00058 19.8 0.2 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EEQ39092.1 - 1.8e-17 62.6 7.2 3e-06 26.7 0.1 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EEQ39092.1 - 2e-17 62.4 10.2 0.0049 16.8 0.2 6.6 6 1 0 6 6 6 5 Kelch motif BUD22 PF09073.10 EEQ39092.1 - 0.0024 17.3 29.1 0.0049 16.3 16.8 2.2 2 0 0 2 2 2 2 BUD22 SART-1 PF03343.13 EEQ39092.1 - 0.062 11.9 32.3 0.013 14.1 15.5 2.1 2 0 0 2 2 2 0 SART-1 family CPSF100_C PF13299.6 EEQ39092.1 - 6 7.0 18.9 0.2 11.8 1.2 3.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Vfa1 PF08432.10 EEQ39092.1 - 7.6 6.8 28.9 0.38 11.1 2.2 3.4 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 CAF1C_H4-bd PF12265.8 EEQ39093.1 - 1.6e-14 53.9 0.0 3.7e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EEQ39093.1 - 3.6e-12 46.6 12.6 0.001 19.9 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39093.1 - 8.8e-07 29.2 2.3 0.03 14.6 0.3 3.6 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PRP1_N PF06424.12 EEQ39094.1 - 3.1e-21 76.3 10.9 1.1e-14 55.0 0.1 3.5 3 1 1 4 4 4 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EEQ39094.1 - 5.6e-14 51.7 19.8 0.21 12.5 0.0 10.7 7 3 6 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ39094.1 - 2.7e-09 37.4 17.2 0.12 12.9 0.1 8.2 6 1 3 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ39094.1 - 2.6e-05 24.3 2.4 2.4 8.7 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ39094.1 - 5.2e-05 23.1 0.8 0.63 10.3 0.0 5.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ39094.1 - 0.00011 22.8 4.2 14 6.4 0.2 5.2 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ39094.1 - 0.00046 19.9 0.0 0.14 12.0 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ39094.1 - 0.002 18.2 0.2 0.54 10.6 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ39094.1 - 1.5 9.2 5.6 5.7 7.3 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MAD PF05557.13 EEQ39095.1 - 1.9e-27 96.0 64.6 2.9e-27 95.3 64.6 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Leu_zip PF15294.6 EEQ39095.1 - 0.0016 18.1 13.9 0.0016 18.1 13.9 4.5 1 1 3 4 4 4 1 Leucine zipper UQ_con PF00179.26 EEQ39096.1 - 8.4e-18 64.4 0.1 9.5e-18 64.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEQ39096.1 - 0.018 15.3 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain Mitochondr_Som1 PF11093.8 EEQ39097.1 - 1.2e-22 79.7 0.5 1.6e-22 79.3 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 CTNNBL PF08216.11 EEQ39097.1 - 0.027 14.7 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear MBOAT PF03062.19 EEQ39098.1 - 2.5e-64 217.8 19.8 2.5e-64 217.8 19.8 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Asp PF00026.23 EEQ39099.1 - 1.3e-10 41.2 0.3 1.9e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic aspartyl protease PAZ PF02170.22 EEQ39099.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 PAZ domain Asp PF00026.23 EEQ39100.1 - 8.7e-11 41.8 0.5 7.3e-10 38.8 0.5 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Vint PF14623.6 EEQ39100.1 - 0.053 13.3 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Hint-domain DUF5514 PF17633.2 EEQ39100.1 - 0.16 12.2 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5514) Asp PF00026.23 EEQ39101.1 - 5.5e-17 62.2 0.3 9.2e-17 61.4 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease PAZ PF02170.22 EEQ39101.1 - 0.1 12.4 1.2 0.99 9.2 0.3 2.2 1 1 0 2 2 2 0 PAZ domain DHR10 PF18595.1 EEQ39104.1 - 0.022 14.8 5.4 0.037 14.1 5.2 1.5 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF3653 PF12375.8 EEQ39104.1 - 0.42 10.8 1.5 7.6 6.7 0.1 2.6 2 1 0 2 2 2 0 Phage protein Na_Ca_ex PF01699.24 EEQ39105.1 - 1.3e-35 122.6 47.2 6.8e-21 74.8 19.1 3.1 4 0 0 4 4 4 2 Sodium/calcium exchanger protein HJURP_C PF12347.8 EEQ39105.1 - 0.099 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Trypan_PARP PF05887.11 EEQ39105.1 - 6.5 6.7 9.8 16 5.4 9.8 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HSP70 PF00012.20 EEQ39106.1 - 2.4e-263 874.8 7.8 2.7e-263 874.6 7.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ39106.1 - 5.4e-16 58.3 0.0 2.5e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EEQ39106.1 - 0.00083 19.1 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EEQ39106.1 - 0.1 11.8 0.8 0.35 10.1 0.1 2.2 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase TMCO5 PF14992.6 EEQ39106.1 - 0.14 11.7 5.5 0.27 10.8 5.5 1.3 1 0 0 1 1 1 0 TMCO5 family GCV_H PF01597.19 EEQ39107.1 - 8.5e-40 135.4 0.2 1e-39 135.2 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EEQ39107.1 - 0.0015 18.5 0.1 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.22 EEQ39107.1 - 0.027 14.3 0.1 0.063 13.1 0.1 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme Synaptobrevin PF00957.21 EEQ39109.1 - 7.1e-27 93.0 1.0 7.9e-27 92.9 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin UPF0258 PF06789.12 EEQ39109.1 - 0.058 13.5 0.2 0.058 13.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF1100 PF06500.11 EEQ39109.1 - 0.063 12.1 0.0 0.069 11.9 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) SNARE PF05739.19 EEQ39109.1 - 4.9 7.2 13.6 8.2 6.5 8.4 2.3 2 1 0 2 2 2 0 SNARE domain Epimerase PF01370.21 EEQ39110.1 - 1.1e-11 44.7 0.1 5.9e-10 39.0 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EEQ39110.1 - 2.8e-11 43.6 0.7 4e-11 43.1 0.7 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EEQ39110.1 - 4.4e-08 33.0 0.5 6.6e-08 32.4 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EEQ39110.1 - 2.3e-06 27.0 0.1 3.4e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EEQ39110.1 - 5.9e-06 25.6 0.4 1.8e-05 24.0 0.1 1.9 1 1 1 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 EEQ39110.1 - 0.00054 20.4 0.1 0.0012 19.3 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EEQ39110.1 - 0.00071 18.7 1.0 0.012 14.6 1.0 2.2 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 EEQ39110.1 - 0.0011 19.2 0.3 0.0021 18.3 0.3 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EEQ39110.1 - 0.0014 18.7 0.2 0.0026 17.8 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EEQ39110.1 - 0.0027 18.0 0.2 0.0045 17.3 0.2 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EEQ39110.1 - 0.0064 15.9 0.2 0.011 15.1 0.2 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EEQ39110.1 - 0.024 13.7 0.4 0.051 12.7 0.1 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.20 EEQ39110.1 - 0.041 14.0 0.7 0.068 13.3 0.7 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2325 PF10087.9 EEQ39110.1 - 0.066 13.3 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Actin PF00022.19 EEQ39112.1 - 3.6e-143 477.1 0.0 1.1e-142 475.4 0.0 1.6 1 1 0 1 1 1 1 Actin GerD PF17898.1 EEQ39112.1 - 0.096 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Spore germination GerD central core domain FAD_binding_2 PF00890.24 EEQ39114.1 - 7.3e-80 269.1 1.3 1e-79 268.6 1.3 1.2 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EEQ39114.1 - 2e-20 72.7 0.0 5.9e-20 71.2 0.0 1.9 2 0 0 2 2 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EEQ39114.1 - 4.8e-14 52.7 0.8 1.5e-13 51.1 0.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EEQ39114.1 - 5e-07 29.4 1.2 1.5e-06 27.8 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EEQ39114.1 - 8e-07 29.2 0.6 4.4e-06 26.8 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ39114.1 - 1.7e-06 27.5 0.6 1.3e-05 24.6 0.2 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ39114.1 - 4.2e-05 22.4 1.6 0.0016 17.2 0.2 2.6 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 EEQ39114.1 - 0.0012 18.2 0.0 0.0017 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EEQ39114.1 - 0.0012 18.0 0.8 0.0012 18.0 0.8 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EEQ39114.1 - 0.0023 17.3 0.0 0.0044 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EEQ39114.1 - 0.0053 16.0 0.3 0.4 9.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EEQ39114.1 - 0.11 11.8 0.9 3.3 6.9 0.1 2.6 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.12 EEQ39114.1 - 0.13 11.3 0.2 0.2 10.6 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SNF2_N PF00176.23 EEQ39116.1 - 8.7e-55 185.8 0.0 1.5e-54 185.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 EEQ39116.1 - 5e-32 111.5 8.1 4.5e-30 105.1 1.9 2.8 3 1 0 3 3 3 2 Rad54 N terminal Helicase_C PF00271.31 EEQ39116.1 - 1.4e-16 60.8 0.0 2.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39116.1 - 6.5e-07 29.5 0.0 2.5e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EEQ39116.1 - 1.4e-05 24.5 0.0 0.0001 21.6 0.0 2.4 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EEQ39116.1 - 0.00012 21.4 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Apt1 PF10351.9 EEQ39116.1 - 1.9 7.2 9.5 3 6.6 9.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ran-binding PF05508.11 EEQ39117.1 - 2.4e-95 319.1 0.1 3.1e-95 318.8 0.1 1.1 1 0 0 1 1 1 1 RanGTP-binding protein BDHCT PF08072.11 EEQ39117.1 - 0.013 15.5 0.0 0.23 11.6 0.0 2.7 3 0 0 3 3 3 0 BDHCT (NUC031) domain TcpS PF17456.2 EEQ39117.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S Copper-fist PF00649.18 EEQ39118.1 - 2.5e-20 71.7 1.3 2.5e-20 71.7 1.3 2.3 2 1 1 3 3 3 1 Copper fist DNA binding domain RTA1 PF04479.13 EEQ39119.1 - 2.3e-28 99.2 7.3 2.6e-28 99.0 7.3 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF2189 PF09955.9 EEQ39119.1 - 0.018 15.3 1.1 0.018 15.3 1.1 2.0 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) DHHC PF01529.20 EEQ39119.1 - 3.9 7.6 8.6 6.8 6.8 1.5 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase RTA1 PF04479.13 EEQ39120.1 - 3.5e-28 98.6 1.9 3.5e-28 98.6 1.9 1.9 2 0 0 2 2 2 1 RTA1 like protein HemY_N PF07219.13 EEQ39120.1 - 0.0037 17.4 1.4 0.0037 17.4 1.4 2.4 2 1 0 2 2 2 1 HemY protein N-terminus DUF4389 PF14333.6 EEQ39120.1 - 0.0041 17.0 1.0 0.0041 17.0 1.0 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4389) HlyIII PF03006.20 EEQ39120.1 - 0.034 13.9 3.9 0.042 13.5 3.9 1.3 1 0 0 1 1 1 0 Haemolysin-III related Pox_A14 PF05767.12 EEQ39120.1 - 0.039 14.1 1.6 0.039 14.1 1.6 2.3 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 FANCI_HD1 PF14679.6 EEQ39120.1 - 0.098 12.6 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 FANCI helical domain 1 ODV-E18 PF10717.9 EEQ39120.1 - 0.64 9.9 3.2 0.43 10.5 0.7 2.0 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF1218 PF06749.12 EEQ39120.1 - 0.82 10.2 5.7 1.1 9.8 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1218) Tetraspanin PF00335.20 EEQ39120.1 - 1.1 8.9 4.6 1.4 8.6 4.6 1.2 1 0 0 1 1 1 0 Tetraspanin family DUF5504 PF17608.2 EEQ39120.1 - 1.8 8.7 6.6 7.4 6.7 1.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5504) DUF4083 PF13314.6 EEQ39120.1 - 1.9 8.5 12.3 0.45 10.5 2.9 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4083) DUF5134 PF17197.4 EEQ39120.1 - 2.3 8.1 5.8 1.3 8.9 1.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF5134) DUF996 PF06195.13 EEQ39120.1 - 4 7.7 12.9 4.8 7.5 3.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF996) Zn_clus PF00172.18 EEQ39121.1 - 5.2e-09 36.1 9.3 1e-08 35.2 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Filament_head PF04732.14 EEQ39121.1 - 0.022 15.6 1.7 0.056 14.3 1.7 1.7 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region RTA1 PF04479.13 EEQ39122.1 - 1.6e-66 223.8 14.0 1.6e-66 223.8 14.0 2.0 2 0 0 2 2 2 1 RTA1 like protein GWT1 PF06423.12 EEQ39122.1 - 0.83 9.8 11.5 0.11 12.6 3.1 2.7 2 1 1 3 3 3 0 GWT1 Tetraspanin PF00335.20 EEQ39122.1 - 1.5 8.5 12.9 4.9 6.8 0.7 2.3 2 0 0 2 2 2 0 Tetraspanin family FMN_dh PF01070.18 EEQ39123.1 - 3.8e-118 394.5 0.1 4.6e-118 394.2 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EEQ39123.1 - 1.1e-24 86.4 0.1 3.5e-24 84.7 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EEQ39123.1 - 9.8e-08 31.5 0.1 1.5e-07 30.9 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EEQ39123.1 - 0.0022 17.1 0.6 0.0062 15.6 0.3 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EEQ39123.1 - 0.012 15.0 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 EEQ39123.1 - 0.031 13.6 0.0 5.6 6.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Big_3_2 PF12245.8 EEQ39123.1 - 0.14 12.5 0.1 0.35 11.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain Myosin_head PF00063.21 EEQ39124.1 - 2.7e-237 789.3 7.2 2.7e-237 789.3 7.2 2.2 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 EEQ39124.1 - 1.4e-25 89.6 0.8 1.4e-25 89.6 0.8 3.1 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 EEQ39124.1 - 1e-18 65.3 29.1 0.00038 20.0 1.5 7.0 7 0 0 7 7 6 5 IQ calmodulin-binding motif AAA_22 PF13401.6 EEQ39124.1 - 0.0076 16.5 0.9 0.057 13.7 0.0 2.9 2 1 1 3 3 3 1 AAA domain Spc7 PF08317.11 EEQ39124.1 - 0.027 13.3 28.5 0.089 11.7 28.2 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein DICT PF10069.9 EEQ39124.1 - 0.032 14.0 4.6 0.97 9.2 1.4 3.1 3 0 0 3 3 3 0 Sensory domain in DIguanylate Cyclases and Two-component system IFT57 PF10498.9 EEQ39124.1 - 0.034 13.1 27.2 0.012 14.6 23.8 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 ABC_tran PF00005.27 EEQ39124.1 - 0.091 13.3 4.6 0.23 12.0 0.0 3.2 2 0 0 2 2 2 0 ABC transporter KASH_CCD PF14662.6 EEQ39124.1 - 0.12 12.1 31.1 0.51 10.1 31.1 2.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH RNA_helicase PF00910.22 EEQ39124.1 - 0.14 12.6 0.5 1.6 9.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.6 EEQ39124.1 - 0.19 12.0 1.7 5 7.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EEQ39124.1 - 0.25 11.7 4.2 0.43 10.9 0.0 3.1 2 1 0 2 2 1 0 AAA ATPase domain T6PP_N PF18572.1 EEQ39124.1 - 0.25 11.2 19.8 3.9 7.4 0.0 4.9 2 1 0 2 2 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain SKA2 PF16740.5 EEQ39124.1 - 0.67 9.8 28.3 0.27 11.0 9.4 4.4 4 1 1 5 5 4 0 Spindle and kinetochore-associated protein 2 TolA_bind_tri PF16331.5 EEQ39124.1 - 0.74 9.9 21.2 2.6 8.2 6.4 4.2 2 1 1 3 3 3 0 TolA binding protein trimerisation PolyA_pol PF01743.20 EEQ39124.1 - 0.82 10.1 4.7 2.9 8.3 3.0 2.9 2 0 0 2 2 2 0 Poly A polymerase head domain BRE1 PF08647.11 EEQ39124.1 - 0.97 9.5 33.6 4.2 7.5 8.8 3.9 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase ADIP PF11559.8 EEQ39124.1 - 1.2 9.3 32.2 0.12 12.4 19.4 3.4 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding HALZ PF02183.18 EEQ39124.1 - 3.9 7.8 19.4 5.6 7.3 0.1 4.8 4 0 0 4 4 3 0 Homeobox associated leucine zipper DUF948 PF06103.11 EEQ39124.1 - 6.6 7.1 14.4 6.8 7.0 4.6 4.3 4 0 0 4 4 3 0 Bacterial protein of unknown function (DUF948) BolA PF01722.18 EEQ39125.1 - 1.8e-28 98.6 2.3 2.3e-28 98.3 2.3 1.2 1 0 0 1 1 1 1 BolA-like protein TMEM208_SND2 PF05620.11 EEQ39126.1 - 1.4e-54 184.4 0.1 1.6e-54 184.2 0.1 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Telomerase_RBD PF12009.8 EEQ39127.1 - 0.17 12.0 3.6 0.43 10.7 0.2 2.8 1 1 2 3 3 3 0 Telomerase ribonucleoprotein complex - RNA binding domain Amidohydro_1 PF01979.20 EEQ39128.1 - 6.9e-74 249.2 0.2 8.3e-74 248.9 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ39128.1 - 5.4e-20 72.3 0.1 5.8e-15 55.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family MRP PF09387.10 EEQ39128.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP SPX PF03105.19 EEQ39129.1 - 5.2e-40 138.6 17.3 7.4e-25 88.7 7.6 2.4 2 1 1 3 3 3 2 SPX domain Na_sulph_symp PF00939.19 EEQ39129.1 - 6.6e-26 91.4 39.1 1.2e-25 90.6 39.1 1.4 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EEQ39129.1 - 2.2e-24 86.2 67.2 1.4e-21 77.0 42.6 2.1 1 1 1 2 2 2 2 Citrate transporter DUF223 PF02721.14 EEQ39129.1 - 0.05 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF223 UCH PF00443.29 EEQ39130.1 - 2.9e-26 92.5 2.3 8.5e-25 87.7 0.8 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ChlamPMP_M PF07548.11 EEQ39130.1 - 0.0056 16.7 0.1 0.042 13.8 0.2 2.3 2 0 0 2 2 2 1 Chlamydia polymorphic membrane protein middle domain Nitr_red_assoc PF09655.10 EEQ39130.1 - 0.009 16.7 0.5 0.084 13.5 0.2 2.5 2 0 0 2 2 2 1 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF4894 PF16235.5 EEQ39130.1 - 0.015 15.6 0.0 0.12 12.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4894) Glycoamylase PF10091.9 EEQ39130.1 - 0.061 12.9 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Putative glucoamylase Erg28 PF03694.13 EEQ39130.1 - 0.14 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Erg28 like protein Cyt-b5 PF00173.28 EEQ39131.1 - 2.9e-22 78.6 0.0 3.7e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain 5-FTHF_cyc-lig PF01812.20 EEQ39132.1 - 2.7e-42 144.7 0.0 3.1e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family SET PF00856.28 EEQ39133.1 - 1.9e-15 57.7 0.1 3.7e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 SET domain HTH_21 PF13276.6 EEQ39133.1 - 0.02 15.0 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 HTH-like domain 4HBT PF03061.22 EEQ39134.1 - 0.027 14.8 0.0 0.053 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily PI-PLC-X PF00388.19 EEQ39135.1 - 1.7e-53 180.1 0.0 3.8e-53 179.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EEQ39135.1 - 3.8e-43 146.5 0.3 9.4e-43 145.2 0.3 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 EEQ39135.1 - 6.2e-05 23.4 0.1 0.00015 22.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like C2 PF00168.30 EEQ39135.1 - 9.1e-05 22.7 0.0 0.00038 20.7 0.0 2.1 1 0 0 1 1 1 1 C2 domain DUF4734 PF15881.5 EEQ39135.1 - 0.013 15.6 0.0 4.4 7.5 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4734) DUF4611 PF15387.6 EEQ39135.1 - 3.4 7.9 5.7 25 5.2 3.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Bystin PF05291.11 EEQ39136.1 - 4.8e-121 403.6 0.1 4.8e-121 403.6 0.1 1.7 2 0 0 2 2 2 1 Bystin Nop14 PF04147.12 EEQ39136.1 - 0.045 12.0 11.3 0.058 11.6 11.3 1.1 1 0 0 1 1 1 0 Nop14-like family MatE PF01554.18 EEQ39137.1 - 4e-37 127.4 10.8 4e-37 127.4 10.8 1.4 2 0 0 2 2 2 1 MatE Polysacc_synt_C PF14667.6 EEQ39137.1 - 6.8e-09 35.9 3.8 6.8e-09 35.9 3.8 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain MurJ PF03023.14 EEQ39137.1 - 1.6e-05 23.8 8.5 1.6e-05 23.8 8.5 1.3 1 1 0 1 1 1 1 Lipid II flippase MurJ Rcd1 PF04078.13 EEQ39138.1 - 3.2e-114 380.6 4.8 5.4e-114 379.8 4.8 1.3 1 1 0 1 1 1 1 Cell differentiation family, Rcd1-like RasGEF_N PF00618.20 EEQ39138.1 - 0.0052 17.0 0.6 0.061 13.6 0.1 2.3 2 0 0 2 2 2 1 RasGEF N-terminal motif HMA PF00403.26 EEQ39139.1 - 2.8e-15 56.5 0.1 5.9e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EEQ39139.1 - 3.4e-05 24.0 0.0 5.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SOG2 PF10428.9 EEQ39140.1 - 2.1e-59 202.1 22.9 1.7e-31 110.0 2.5 5.3 3 1 1 5 5 5 3 RAM signalling pathway protein LRR_8 PF13855.6 EEQ39140.1 - 2e-12 46.7 8.7 8.7e-08 31.8 3.3 2.9 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EEQ39140.1 - 5.6e-11 42.5 11.8 1.3e-07 31.8 1.0 4.5 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EEQ39140.1 - 0.0034 16.9 0.9 0.041 13.4 0.2 2.5 1 1 1 2 2 2 2 Leucine-rich repeat Glutaredoxin2_C PF04399.13 EEQ39140.1 - 0.031 14.1 1.7 0.14 12.0 0.7 2.5 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain LRR_1 PF00560.33 EEQ39140.1 - 0.14 12.8 9.7 11 7.1 0.1 5.4 6 0 0 6 6 6 0 Leucine Rich Repeat TauD PF02668.16 EEQ39142.1 - 1.6e-36 126.5 0.2 4.3e-36 125.1 0.2 1.6 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CN_hydrolase PF00795.22 EEQ39143.1 - 2.8e-42 144.9 0.0 3.9e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EEQ39143.1 - 1.4e-24 86.5 0.0 4.4e-24 84.9 0.0 1.7 1 1 0 1 1 1 1 NAD synthase dCMP_cyt_deam_1 PF00383.23 EEQ39144.1 - 1.4e-20 73.0 0.2 2.1e-20 72.5 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEQ39144.1 - 3.8e-13 49.4 0.0 7.6e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 EEQ39144.1 - 2.2e-05 24.3 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase SNAD4 PF18750.1 EEQ39144.1 - 0.0018 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 EEQ39144.1 - 0.0029 17.7 0.1 0.0048 17.0 0.1 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC_N PF08210.11 EEQ39144.1 - 0.0032 17.4 0.1 0.005 16.8 0.1 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain APOBEC2 PF18772.1 EEQ39144.1 - 0.013 15.6 0.1 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 APOBEC2 Bd3614-deam PF14439.6 EEQ39144.1 - 0.014 15.5 0.8 0.063 13.4 0.8 1.9 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC3 PF18771.1 EEQ39144.1 - 0.018 15.2 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 APOBEC3 APOBEC4_like PF18774.1 EEQ39144.1 - 0.024 14.6 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase XOO_2897-deam PF14440.6 EEQ39144.1 - 0.13 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase Abhydrolase_6 PF12697.7 EEQ39145.1 - 2e-20 74.3 0.0 2.9e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ39145.1 - 1.9e-19 70.3 0.1 2.7e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ39145.1 - 1.2e-14 54.2 0.1 1.8e-14 53.6 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EEQ39145.1 - 0.0017 18.5 0.0 0.003 17.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 EEQ39145.1 - 0.0021 17.0 0.0 0.0082 15.1 0.0 1.9 2 0 0 2 2 2 1 Chlorophyllase enzyme Ribosomal_S26e PF01283.19 EEQ39145.1 - 0.0065 16.9 0.2 8.1 6.9 0.8 2.5 2 0 0 2 2 2 2 Ribosomal protein S26e LIDHydrolase PF10230.9 EEQ39145.1 - 0.011 15.3 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 EEQ39145.1 - 0.014 15.3 0.1 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 EEQ39145.1 - 0.036 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 EEQ39145.1 - 0.091 12.1 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 EEQ39145.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Sigma70_r2 PF04542.14 EEQ39145.1 - 0.11 12.2 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 region 2 Abhydrolase_5 PF12695.7 EEQ39145.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Dsh_C PF12316.8 EEQ39145.1 - 3.8 7.9 7.5 1.9 8.9 4.8 1.7 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal YkpC PF17447.2 EEQ39145.1 - 4.3 8.4 6.4 3.3 8.7 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized YkpC-like Candida_ALS_N PF11766.8 EEQ39146.1 - 5.9e-67 225.5 7.9 5.9e-67 225.5 7.9 4.8 4 1 1 5 5 5 1 Cell-wall agglutinin N-terminal ligand-sugar binding Candida_ALS PF05792.13 EEQ39146.1 - 3.1e-59 197.2 1149.4 0.00017 22.1 14.5 58.4 58 2 1 59 59 59 50 Candida agglutinin-like (ALS) DPBB_1 PF03330.18 EEQ39147.1 - 3.6e-09 36.8 0.0 9.4e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EEQ39147.1 - 0.0016 18.3 0.1 0.0028 17.5 0.1 1.4 1 0 0 1 1 1 1 Barwin family Ndc1_Nup PF09531.10 EEQ39147.1 - 1 7.9 9.2 1.2 7.8 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 EEQ39147.1 - 1.6 7.8 19.6 2 7.5 19.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 EEQ39147.1 - 1.7 7.2 13.5 1.8 7.1 13.5 1.0 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 EEQ39147.1 - 1.8 8.5 12.0 2.2 8.2 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 EEQ39147.1 - 1.9 8.0 7.7 2.5 7.6 7.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 EEQ39147.1 - 4.8 5.6 7.3 6 5.3 7.3 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EEQ39147.1 - 6.6 5.4 7.4 9.7 4.8 7.4 1.3 1 0 0 1 1 1 0 Presenilin Ssl1 PF04056.14 EEQ39148.1 - 5.9e-66 222.0 0.0 8.6e-66 221.4 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EEQ39148.1 - 1.2e-14 54.2 12.0 1.2e-14 54.2 12.0 2.9 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EEQ39148.1 - 1.2e-13 51.6 0.0 2.6e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-HIT PF04438.16 EEQ39148.1 - 0.013 15.3 5.9 0.013 15.3 5.9 3.6 3 1 0 3 3 3 0 HIT zinc finger VWA PF00092.28 EEQ39148.1 - 0.019 15.2 0.0 0.03 14.6 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain CTU2 PF10288.9 EEQ39148.1 - 0.055 13.7 2.0 0.13 12.5 2.0 1.7 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 FYDLN_acid PF09538.10 EEQ39148.1 - 0.069 13.8 0.6 0.069 13.8 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF2722 PF10846.8 EEQ39149.1 - 0.12 11.3 1.7 0.17 10.8 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 EEQ39149.1 - 0.78 9.3 6.6 1.1 8.8 6.6 1.1 1 0 0 1 1 1 0 Spt20 family Spt5-NGN PF03439.13 EEQ39150.1 - 1.2e-23 82.7 0.0 2.9e-23 81.6 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EEQ39150.1 - 2.3e-22 79.8 15.3 2.3e-22 79.8 15.3 3.6 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EEQ39150.1 - 9.7e-13 47.6 26.2 2.9e-08 33.4 1.0 5.9 6 0 0 6 6 6 3 KOW motif Pribosyltran PF00156.27 EEQ39152.1 - 1.1e-14 54.3 0.0 1.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EEQ39152.1 - 0.0062 16.0 0.0 0.009 15.5 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Med13_N PF11597.8 EEQ39154.1 - 3.3e-61 207.4 2.1 5.4e-61 206.7 2.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 EEQ39154.1 - 4.6e-18 65.6 1.2 2e-17 63.5 0.0 2.8 2 2 0 2 2 2 1 Mediator complex subunit 13 C-terminal domain DUF5600 PF18150.1 EEQ39155.1 - 0.089 13.4 1.9 0.17 12.5 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5600) DUF1192 PF06698.11 EEQ39155.1 - 0.21 11.7 2.2 0.56 10.3 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) PAT1 PF09770.9 EEQ39155.1 - 1.1 7.5 25.8 1.4 7.1 25.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cyclin_N PF00134.23 EEQ39158.1 - 5.1e-10 39.2 0.0 8.9e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEQ39159.1 - 1e-32 112.7 0.0 9.1e-32 109.7 0.0 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 EEQ39159.1 - 8.5e-24 83.7 0.0 3.6e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain PTCB-BRCT PF12738.7 EEQ39161.1 - 3.3e-25 87.8 0.1 2.6e-16 59.3 0.0 3.3 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 EEQ39161.1 - 1.3e-18 67.2 0.0 4.3e-06 27.0 0.0 3.7 3 0 0 3 3 3 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EEQ39161.1 - 3.9e-18 65.6 0.0 1.5e-05 25.3 0.0 4.6 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EEQ39161.1 - 5e-16 58.4 0.0 1.5e-13 50.5 0.1 3.5 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EEQ39161.1 - 1.2e-06 28.5 0.0 0.0081 16.2 0.0 3.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EEQ39161.1 - 4.2e-05 23.7 1.0 0.0063 16.8 0.0 3.5 3 0 0 3 3 3 1 DNA ligase 3 BRCT domain RNA_pol_Rpc4 PF05132.14 EEQ39161.1 - 0.019 15.4 0.3 0.019 15.4 0.3 4.3 2 1 1 3 3 3 0 RNA polymerase III RPC4 DUF4471 PF14740.6 EEQ39161.1 - 0.39 9.9 15.3 1.3 8.2 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4471) DUF572 PF04502.13 EEQ39161.1 - 0.88 9.1 35.5 2.7 7.6 23.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Otopetrin PF03189.13 EEQ39161.1 - 2.1 7.1 5.3 0.21 10.4 0.1 1.8 2 0 0 2 2 2 0 Otopetrin ENTH PF01417.20 EEQ39163.1 - 6e-43 145.9 0.1 8.6e-43 145.4 0.1 1.2 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 EEQ39163.1 - 1.9e-06 27.4 12.4 0.0015 18.3 1.1 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.16 EEQ39163.1 - 4.6e-05 22.6 0.4 7e-05 22.0 0.4 1.4 1 1 0 1 1 1 1 ANTH domain Atx10homo_assoc PF09759.9 EEQ39164.1 - 8.7e-37 125.1 1.7 1.8e-36 124.1 0.5 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain RYDR_ITPR PF01365.21 EEQ39164.1 - 0.031 13.7 0.1 0.52 9.7 0.1 2.4 2 0 0 2 2 2 0 RIH domain Thr_synth_N PF14821.6 EEQ39165.1 - 2.2e-29 101.5 0.0 7.7e-29 99.7 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EEQ39165.1 - 1.7e-17 63.8 0.0 2.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Tam41_Mmp37 PF09139.11 EEQ39166.1 - 7.4e-93 311.5 0.0 1e-91 307.8 0.0 1.9 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial DUF1736 PF08409.11 EEQ39166.1 - 0.014 15.3 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) Gti1_Pac2 PF09729.9 EEQ39167.1 - 8.6e-35 120.5 1.2 4.3e-30 105.2 0.1 2.3 1 1 1 2 2 2 2 Gti1/Pac2 family DUF3614 PF12267.8 EEQ39167.1 - 0.58 10.6 2.1 0.56 10.7 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) SAP30_Sin3_bdg PF13867.6 EEQ39168.1 - 4.5e-08 33.3 0.0 3.6e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 WD40 PF00400.32 EEQ39171.1 - 9.5e-25 86.4 5.8 0.00021 22.0 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39171.1 - 1.7e-17 63.4 0.0 0.008 16.5 0.0 5.7 3 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EEQ39171.1 - 0.00022 21.2 0.0 0.032 14.1 0.0 3.3 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 EEQ39171.1 - 0.0093 15.8 0.2 0.019 14.8 0.2 1.5 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EEQ39171.1 - 0.054 13.4 0.1 21 5.2 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EEQ39171.1 - 0.13 11.2 0.0 17 4.3 0.0 3.1 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CUE PF02845.16 EEQ39173.1 - 6.6e-09 35.3 0.0 1.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain Cue1_U7BR PF18499.1 EEQ39173.1 - 0.014 15.4 3.4 0.15 12.2 3.4 2.3 1 1 0 1 1 1 0 Ubc7p-binding region of Cue1 Peptidase_M18 PF02127.15 EEQ39174.1 - 4.8e-119 398.0 0.0 2.5e-117 392.3 0.0 2.2 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) RR_TM4-6 PF06459.12 EEQ39174.1 - 2.3 8.0 20.7 4 7.2 20.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 EEQ39174.1 - 6.4 6.8 19.4 9.5 6.2 19.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PA26 PF04636.13 EEQ39174.1 - 7.5 5.4 14.0 11 4.8 14.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Sugar_tr PF00083.24 EEQ39176.1 - 9.4e-89 298.3 17.7 1.1e-88 298.1 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ39176.1 - 2.6e-28 99.0 26.4 1.5e-19 70.2 3.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EEQ39176.1 - 0.017 13.6 1.2 0.17 10.3 0.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Phage_holin_2_1 PF04971.12 EEQ39176.1 - 4.8 7.3 6.5 3.5 7.7 0.4 3.2 3 1 0 3 3 3 0 Bacteriophage P21 holin S Filament_head PF04732.14 EEQ39177.1 - 0.035 15.0 5.8 0.035 15.0 5.8 2.3 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Flocculin_t3 PF13928.6 EEQ39178.1 - 0.00037 20.9 3.3 0.001 19.5 3.3 1.8 1 0 0 1 1 1 1 Flocculin type 3 repeat Mucin-like PF16058.5 EEQ39178.1 - 1 9.5 19.3 0.96 9.6 17.9 1.4 1 1 0 1 1 1 0 Mucin-like NEMP PF10225.9 EEQ39179.1 - 0.79 9.3 1.9 1.5 8.4 1.9 1.4 1 0 0 1 1 1 0 NEMP family MFS_1 PF07690.16 EEQ39180.1 - 5.9e-27 94.5 8.5 5.9e-27 94.5 8.5 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ39180.1 - 0.0054 16.1 0.2 0.025 13.9 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB ERG2_Sigma1R PF04622.12 EEQ39180.1 - 0.055 12.8 0.7 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 ERG2 and Sigma1 receptor like protein DUF4293 PF14126.6 EEQ39180.1 - 0.056 13.7 0.5 0.67 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Ribosomal_L7Ae PF01248.26 EEQ39182.1 - 2.8e-26 91.1 0.7 3.6e-26 90.7 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EEQ39182.1 - 0.00021 21.3 0.0 0.0003 20.9 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Swi3 PF07962.12 EEQ39182.1 - 0.071 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Replication Fork Protection Component Swi3 ATPase_2 PF01637.18 EEQ39182.1 - 0.099 12.5 1.4 0.11 12.4 0.6 1.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea VirionAssem_T7 PF11653.8 EEQ39182.1 - 0.15 12.6 5.4 0.21 12.1 5.3 1.4 1 1 0 1 1 1 0 Bacteriophage T7 virion assembly protein Adaptin_N PF01602.20 EEQ39184.1 - 5.5e-102 342.0 11.8 8.1e-102 341.4 11.8 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EEQ39184.1 - 2.2e-56 189.3 0.0 6.1e-56 187.9 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EEQ39184.1 - 1.2e-55 187.3 0.4 1.2e-55 187.3 0.4 2.0 2 0 0 2 2 2 1 Coatomer beta C-terminal region Cnd1 PF12717.7 EEQ39184.1 - 4.6e-09 36.5 8.5 8.7e-08 32.4 0.1 3.5 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ39184.1 - 1.4e-07 31.8 0.1 0.0015 18.8 0.0 5.0 2 2 4 6 6 6 1 HEAT repeats HEAT PF02985.22 EEQ39184.1 - 0.0022 18.1 0.2 0.2 12.0 0.0 3.9 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 EEQ39184.1 - 0.0025 18.0 0.0 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform AP4E_app_platf PF14807.6 EEQ39184.1 - 0.01 16.2 0.5 0.17 12.3 0.0 3.3 3 0 0 3 3 3 0 Adaptin AP4 complex epsilon appendage platform ParcG PF10274.9 EEQ39184.1 - 0.16 12.1 1.8 2.8 8.0 0.1 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein FANCI_S2 PF14676.6 EEQ39184.1 - 0.37 11.1 8.8 0.15 12.3 0.9 3.7 4 0 0 4 4 4 0 FANCI solenoid 2 DUF5578 PF17741.1 EEQ39184.1 - 0.9 8.9 9.9 1.3 8.4 0.1 3.4 1 1 2 3 3 3 0 Family of unknown function (DUF5578) Peptidase_M24 PF00557.24 EEQ39186.1 - 1e-14 54.8 0.0 1.8e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.29 EEQ39187.1 - 1.9e-13 50.1 26.2 5e-09 35.9 11.4 2.5 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 EEQ39187.1 - 0.072 12.7 17.9 0.13 11.8 5.7 3.5 3 0 0 3 3 3 0 PHD-finger L51_S25_CI-B8 PF05047.16 EEQ39189.1 - 3.1e-10 39.8 0.1 5.2e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ArgJ PF01960.18 EEQ39190.1 - 4.7e-126 420.5 5.8 5.6e-126 420.3 5.8 1.0 1 0 0 1 1 1 1 ArgJ family FRB_dom PF08771.11 EEQ39191.1 - 2.3 8.7 4.7 5.1 7.6 4.7 1.5 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain adh_short PF00106.25 EEQ39193.1 - 1.3e-40 139.0 0.0 2.6e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ39193.1 - 5.7e-29 101.3 0.0 8.1e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ39193.1 - 1.3e-07 31.8 0.4 1.9e-06 27.9 0.4 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ39193.1 - 0.011 15.3 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ39193.1 - 0.15 11.1 0.3 0.2 10.6 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CFEM PF05730.11 EEQ39194.1 - 1.3e-09 38.0 2.3 4.2e-09 36.4 2.3 1.9 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.11 EEQ39195.1 - 1.3e-37 127.7 45.5 2.3e-12 46.8 9.9 3.5 3 0 0 3 3 3 3 CFEM domain HCV_NS4a PF01006.20 EEQ39195.1 - 0.12 12.2 6.6 19 5.1 0.2 4.2 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a Iwr1 PF08574.10 EEQ39196.1 - 6.6e-15 55.9 12.3 6.6e-15 55.9 12.3 3.7 2 1 1 3 3 3 1 Transcription factor Iwr1 RNA_pol PF00940.19 EEQ39197.1 - 2.9e-31 108.7 0.0 3.4e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RNA_pol PF00940.19 EEQ39198.1 - 1.2e-83 281.2 0.0 2.1e-83 280.5 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EEQ39198.1 - 8.6e-19 68.1 0.0 8.3e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal ACDC PF14733.6 EEQ39198.1 - 0.021 15.1 0.1 0.059 13.7 0.1 1.8 1 0 0 1 1 1 0 AP2-coincident C-terminal DUF4876 PF16215.5 EEQ39199.1 - 0.11 12.5 0.2 2.1 8.3 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4876) TRAPP PF04051.16 EEQ39200.1 - 2.9e-37 127.6 0.0 3.5e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component RhoGEF PF00621.20 EEQ39201.1 - 1.8e-05 25.1 0.0 4.4e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 RhoGEF domain DUF866 PF05907.13 EEQ39201.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Toxin_18 PF08087.11 EEQ39202.1 - 0.25 11.4 0.4 0.25 11.4 0.4 2.2 3 0 0 3 3 3 0 Conotoxin O-superfamily DUF3382 PF11862.8 EEQ39203.1 - 0.25 11.6 1.1 6.7 7.1 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3382) RRM_1 PF00076.22 EEQ39204.1 - 2.1e-12 46.7 0.0 1.2e-10 41.0 0.0 3.0 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.9 EEQ39204.1 - 0.00095 17.6 29.7 0.0011 17.3 29.7 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 PIP5K PF01504.18 EEQ39204.1 - 0.07 12.3 9.4 0.14 11.4 9.4 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF572 PF04502.13 EEQ39204.1 - 0.14 11.7 18.1 0.25 10.9 18.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.12 EEQ39204.1 - 0.22 11.3 20.2 0.33 10.7 20.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Borrelia_P83 PF05262.11 EEQ39204.1 - 0.25 9.8 16.7 0.32 9.4 16.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 EEQ39204.1 - 0.45 9.2 29.2 0.72 8.5 29.2 1.3 1 0 0 1 1 1 0 Presenilin SAPS PF04499.15 EEQ39204.1 - 0.9 8.2 15.5 1.3 7.7 15.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4746 PF15928.5 EEQ39204.1 - 1.4 8.2 12.5 2.3 7.6 12.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CCSAP PF15748.5 EEQ39204.1 - 1.9 8.6 30.5 0.083 13.1 24.4 1.8 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated GREB1 PF15782.5 EEQ39204.1 - 3.1 4.8 27.2 4.4 4.3 27.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 EEQ39204.1 - 3.6 6.6 22.3 6.1 5.8 22.3 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NPR3 PF03666.13 EEQ39204.1 - 4.7 5.9 23.8 8.1 5.1 23.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 EEQ39204.1 - 4.8 7.1 19.2 10 6.0 19.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A Peptidase_C58 PF03543.14 EEQ39204.1 - 4.9 6.8 26.5 11 5.6 26.5 1.5 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Hamartin PF04388.12 EEQ39204.1 - 5.3 5.6 31.3 7.7 5.0 31.3 1.3 1 0 0 1 1 1 0 Hamartin protein Peptidase_S64 PF08192.11 EEQ39204.1 - 5.8 5.3 18.8 10 4.5 18.8 1.3 1 0 0 1 1 1 0 Peptidase family S64 CDK5_activator PF03261.15 EEQ39204.1 - 9.1 5.7 19.2 15 5.0 19.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein EPL1 PF10513.9 EEQ39204.1 - 9.9 6.5 26.5 1.8 8.9 21.7 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Pkinase PF00069.25 EEQ39205.1 - 3.6e-41 141.3 0.0 5.3e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39205.1 - 1.6e-25 89.9 0.0 2.5e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ39205.1 - 1.5e-07 31.1 0.0 2.4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ39205.1 - 0.00027 20.4 0.0 0.00042 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EEQ39205.1 - 0.022 13.8 0.5 0.12 11.5 0.1 2.0 1 1 1 2 2 2 0 Seadornavirus VP7 SH3_2 PF07653.17 EEQ39206.1 - 3e-06 26.8 0.0 6.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EEQ39206.1 - 7.1e-05 22.3 0.1 0.00028 20.4 0.1 2.0 1 1 0 1 1 1 1 SH3 domain BAR PF03114.18 EEQ39206.1 - 0.00047 19.9 2.4 0.00047 19.9 2.4 2.2 2 0 0 2 2 2 1 BAR domain DHR10 PF18595.1 EEQ39206.1 - 0.23 11.5 4.7 7.2 6.7 0.2 2.7 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Abhydrolase_1 PF00561.20 EEQ39208.1 - 3.9e-16 59.5 0.0 6.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ39208.1 - 7.2e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ39208.1 - 0.00029 21.5 0.1 0.00062 20.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 EEQ39208.1 - 0.15 11.7 0.1 0.37 10.4 0.0 1.6 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) LSM14 PF12701.7 EEQ39209.1 - 1.7e-26 92.1 0.0 2.5e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 EEQ39209.1 - 8.1e-05 22.7 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 EEQ39209.1 - 0.0056 17.5 13.2 0.034 15.0 2.9 3.6 2 1 1 3 3 3 2 FDF domain MCLC PF05934.11 EEQ39209.1 - 2.8 6.6 6.4 2.7 6.6 5.7 1.2 1 1 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF1631 PF07793.11 EEQ39209.1 - 3 6.1 7.5 3.3 6.0 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Med26 PF08711.11 EEQ39210.1 - 2.9e-09 36.8 0.3 1.1e-08 35.0 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Ribosom_S12_S23 PF00164.25 EEQ39211.1 - 3.1e-51 171.8 0.2 4e-51 171.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Mito_carr PF00153.27 EEQ39212.1 - 5.1e-53 177.0 1.8 3.3e-18 65.4 0.5 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Paz_1 PF18349.1 EEQ39212.1 - 0.023 14.6 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 PAZ domain ANAPC4_WD40 PF12894.7 EEQ39213.1 - 0.0017 18.6 0.3 0.015 15.6 0.0 2.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Phage_holin_3_5 PF16085.5 EEQ39213.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage holin Hol, superfamily III LisH PF08513.11 EEQ39213.1 - 0.13 12.2 1.4 0.7 10.0 0.1 2.6 2 0 0 2 2 2 0 LisH WD40 PF00400.32 EEQ39213.1 - 0.32 11.9 3.0 2.1 9.3 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat DBR1 PF05011.13 EEQ39214.1 - 7.4e-21 75.0 0.0 1.8e-20 73.8 0.0 1.6 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain NAD_binding_1 PF00175.21 EEQ39215.1 - 5.7e-30 104.2 0.0 8.6e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ39215.1 - 7.7e-24 83.9 0.0 1.3e-23 83.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEQ39215.1 - 2.3e-05 24.5 0.0 0.00029 21.0 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Carb_kinase PF01256.17 EEQ39216.1 - 3.2e-50 170.9 0.2 5.5e-49 166.8 0.2 2.1 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 EEQ39216.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase Pex24p PF06398.11 EEQ39217.1 - 0.052 12.5 0.0 0.11 11.5 0.0 1.5 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin NAD_Gly3P_dh_N PF01210.23 EEQ39219.1 - 2.4e-51 173.8 0.0 4.8e-51 172.8 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EEQ39219.1 - 3.5e-41 140.8 0.1 5.9e-41 140.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EEQ39219.1 - 0.0035 17.9 0.0 0.41 11.3 0.0 2.5 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NUDIX PF00293.28 EEQ39220.1 - 2.5e-10 40.5 0.0 4.1e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain LYRIC PF15686.5 EEQ39221.1 - 0.034 13.7 24.3 0.044 13.4 24.3 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Asp-B-Hydro_N PF05279.11 EEQ39221.1 - 0.093 12.8 25.5 0.12 12.4 25.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region BUD22 PF09073.10 EEQ39221.1 - 0.53 9.6 38.9 0.72 9.1 38.9 1.1 1 0 0 1 1 1 0 BUD22 DUF572 PF04502.13 EEQ39221.1 - 1.8 8.1 28.1 2.3 7.8 28.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PI3K_1B_p101 PF10486.9 EEQ39221.1 - 2.2 6.0 18.3 2.6 5.7 18.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Brix PF04427.18 EEQ39222.1 - 2e-44 152.0 3.1 2e-44 152.0 3.1 1.5 2 0 0 2 2 2 1 Brix domain DEAD PF00270.29 EEQ39223.1 - 6.6e-50 169.3 0.0 1.2e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ39223.1 - 6.2e-32 110.2 0.0 3e-31 108.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39223.1 - 9e-06 25.8 0.0 2.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EEQ39223.1 - 0.00018 20.8 0.1 0.00037 19.8 0.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_30 PF13604.6 EEQ39223.1 - 0.0011 18.7 0.0 0.0056 16.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain SBF_like PF13593.6 EEQ39223.1 - 0.16 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) FYVE PF01363.21 EEQ39224.1 - 3.4e-19 68.8 6.0 3.4e-19 68.8 6.0 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EEQ39224.1 - 4.4e-09 36.5 24.9 3.3e-07 30.5 6.9 4.2 4 0 0 4 4 4 2 Ring finger domain zf-RING_11 PF17123.5 EEQ39224.1 - 3.1e-05 23.6 7.6 3.1e-05 23.6 7.6 2.9 3 0 0 3 3 3 1 RING-like zinc finger DUF2039 PF10217.9 EEQ39224.1 - 0.00065 20.0 5.5 0.14 12.5 0.0 3.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2039) DUF4428 PF14471.6 EEQ39224.1 - 0.0019 18.1 1.7 0.0019 18.1 1.7 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4428) zf-C3HC4 PF00097.25 EEQ39224.1 - 0.01 15.7 4.0 0.01 15.7 4.0 4.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEQ39224.1 - 0.015 14.9 5.4 0.015 14.9 5.4 2.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EEQ39224.1 - 0.024 14.5 5.1 0.024 14.5 5.1 4.4 4 1 0 4 4 3 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ39224.1 - 0.85 9.5 0.1 0.85 9.5 0.1 4.5 4 1 1 5 5 5 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ39224.1 - 3.3 7.7 28.1 1.6 8.8 4.6 4.2 3 1 1 4 4 4 0 zinc-RING finger domain FYVE_2 PF02318.16 EEQ39224.1 - 4.4 7.5 16.8 0.039 14.2 6.1 2.8 3 1 0 3 3 3 0 FYVE-type zinc finger Med21 PF11221.8 EEQ39225.1 - 3.9e-48 163.4 0.2 4.4e-48 163.2 0.2 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Spore_III_AB PF09548.10 EEQ39225.1 - 0.017 15.3 0.2 0.025 14.7 0.2 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Cdh1_DBD_1 PF18196.1 EEQ39225.1 - 0.032 14.6 0.4 0.055 13.8 0.4 1.3 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 EspA PF03433.13 EEQ39225.1 - 0.11 12.3 0.5 0.21 11.4 0.2 1.6 2 0 0 2 2 2 0 EspA-like secreted protein Med2 PF11214.8 EEQ39225.1 - 1.1 9.4 6.3 6.7 6.9 0.0 2.7 2 1 0 2 2 2 0 Mediator complex subunit 2 PMT PF02366.18 EEQ39226.1 - 2e-71 240.5 14.6 2e-71 240.5 14.6 2.3 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EEQ39226.1 - 2.7e-49 167.5 13.5 2.7e-49 167.5 13.5 1.8 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EEQ39226.1 - 1.8e-21 76.9 1.1 3e-21 76.1 1.1 1.4 1 0 0 1 1 1 1 MIR domain DUF569 PF04601.13 EEQ39226.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF569) Mucin_bdg PF03272.13 EEQ39226.1 - 0.05 13.6 0.5 9 6.4 0.0 2.3 1 1 1 2 2 2 0 Putative mucin or carbohydrate-binding module O_Spanin_T7 PF17531.2 EEQ39226.1 - 0.14 12.2 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 outer-membrane spanin sub-unit SLAC1 PF03595.17 EEQ39229.1 - 0.089 12.0 5.4 0.12 11.6 5.4 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel Ribosomal_S27e PF01667.17 EEQ39230.1 - 3.6e-29 100.2 4.9 4.5e-29 99.9 4.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 EEQ39230.1 - 0.036 14.3 1.7 0.042 14.1 1.7 1.2 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 EEQ39230.1 - 0.094 12.3 3.6 0.13 11.8 3.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Rsm22 PF09243.10 EEQ39231.1 - 8.6e-24 84.3 0.7 3.3e-07 29.9 0.0 4.3 2 2 1 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EEQ39231.1 - 3.6e-05 23.6 0.0 8.9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ApoO PF09769.9 EEQ39232.1 - 2.9e-37 127.5 0.5 1.3e-36 125.4 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein O Phage_holin_6_1 PF09682.10 EEQ39232.1 - 0.079 13.4 1.9 0.55 10.7 0.6 2.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Elong_Iki1 PF10483.9 EEQ39233.1 - 0.37 10.2 5.9 0.39 10.2 1.7 2.2 1 1 1 2 2 2 0 Elongator subunit Iki1 Mito_carr PF00153.27 EEQ39235.1 - 5.1e-60 199.4 0.2 1.4e-22 79.4 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EEQ39235.1 - 0.0022 17.2 0.1 0.0096 15.1 0.0 2.1 3 0 0 3 3 3 1 Gammaproteobacterial serine protease Raptor_N PF14538.6 EEQ39236.1 - 1.4e-66 223.0 0.0 2.6e-66 222.1 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EEQ39236.1 - 2.6e-07 31.2 3.8 1.3 10.0 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.22 EEQ39236.1 - 0.00079 19.5 0.9 12 6.5 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EEQ39236.1 - 0.03 14.4 0.0 0.3 11.1 0.0 2.5 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ39236.1 - 0.038 14.4 0.0 0.72 10.3 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats MFAP1 PF06991.11 EEQ39238.1 - 3.1e-17 63.2 14.6 1.2e-14 54.7 13.3 2.2 1 1 1 2 2 2 2 Microfibril-associated/Pre-mRNA processing Iron_permease PF04120.12 EEQ39238.1 - 0.56 10.0 2.0 0.93 9.3 2.0 1.3 1 0 0 1 1 1 0 Low affinity iron permease CDO_I PF05995.12 EEQ39239.1 - 1.1e-42 145.2 0.0 1.6e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EEQ39239.1 - 0.0052 16.3 0.8 0.074 12.5 0.8 2.2 1 1 0 1 1 1 1 PCO_ADO SLAC1 PF03595.17 EEQ39240.1 - 2.3e-75 253.9 44.1 2.7e-75 253.7 44.1 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5056 PF16479.5 EEQ39240.1 - 0.21 11.9 0.0 0.21 11.9 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) Trs65 PF12735.7 EEQ39241.1 - 1.5e-64 218.4 1.0 3.9e-64 217.0 1.0 1.7 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Peptidase_M3 PF01432.20 EEQ39242.1 - 1.9e-148 495.5 3.6 2.8e-148 495.0 3.6 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 EEQ39242.1 - 0.03 13.9 0.2 0.059 13.0 0.2 1.4 1 0 0 1 1 1 0 Peptidase M50B-like Rx_N PF18052.1 EEQ39242.1 - 0.12 12.7 1.8 1.1 9.5 0.3 2.8 1 1 1 2 2 2 0 Rx N-terminal domain HGTP_anticodon PF03129.20 EEQ39243.1 - 4.3e-24 84.5 0.3 2.6e-23 82.0 0.1 2.4 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EEQ39243.1 - 5.6e-09 36.2 0.0 2e-08 34.4 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) FMO-like PF00743.19 EEQ39245.1 - 1.3e-13 50.3 3.3 1.4e-11 43.6 3.3 2.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EEQ39245.1 - 6.4e-09 35.5 0.0 0.00023 20.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ39245.1 - 8.2e-09 35.0 1.7 4.5e-08 32.6 0.1 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EEQ39245.1 - 2.1e-08 33.8 0.3 5.7e-06 25.8 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ39245.1 - 2.7e-07 30.7 0.1 2.1e-06 27.9 0.0 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EEQ39245.1 - 7.5e-05 22.1 0.2 0.0023 17.2 0.0 2.7 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 EEQ39245.1 - 0.00011 21.9 0.0 0.0016 18.1 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EEQ39245.1 - 0.00075 19.5 0.0 1 9.4 0.0 3.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.20 EEQ39245.1 - 0.014 15.5 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Trp_halogenase PF04820.14 EEQ39245.1 - 0.092 11.6 0.1 5.5 5.7 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase ABA_GPCR PF12430.8 EEQ39246.1 - 4.2e-51 173.3 9.3 4.2e-51 173.3 9.3 2.3 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EEQ39246.1 - 2e-14 53.4 0.4 7.1e-14 51.7 0.1 2.1 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal SpoIISA_toxin PF14171.6 EEQ39246.1 - 0.041 13.6 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system Mhr1 PF12829.7 EEQ39247.1 - 3e-21 75.3 0.3 6.7e-21 74.2 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Fungal_trans PF04082.18 EEQ39248.1 - 1e-06 28.0 1.9 3.2e-05 23.1 1.9 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ39248.1 - 1.1e-05 25.4 12.3 2.1e-05 24.6 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 EEQ39249.1 - 2.1e-40 138.2 0.0 5.7e-40 136.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ39249.1 - 7.3e-07 28.9 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EEQ39249.1 - 5.4e-05 23.2 0.0 0.0002 21.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EEQ39249.1 - 5.5e-05 23.5 0.0 0.0026 18.0 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ39249.1 - 0.00021 21.7 0.1 0.0044 17.4 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 EEQ39249.1 - 0.00031 20.9 0.0 0.00074 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EEQ39249.1 - 0.00059 19.1 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EEQ39249.1 - 0.0035 17.1 0.0 0.0082 15.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EEQ39249.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ39249.1 - 0.019 14.5 0.0 0.047 13.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EEQ39249.1 - 0.022 15.3 0.0 0.073 13.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEQ39249.1 - 0.024 14.8 0.0 0.053 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEQ39249.1 - 0.027 14.2 0.1 0.084 12.6 0.1 1.9 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EEQ39249.1 - 0.035 14.5 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EEQ39249.1 - 0.042 13.1 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 EEQ39249.1 - 0.044 13.7 0.0 5.2 6.9 0.0 2.3 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EEQ39249.1 - 0.044 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EEQ39249.1 - 0.045 13.1 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EEQ39249.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EEQ39249.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 EEQ39249.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EEQ39249.1 - 0.18 11.9 0.0 0.46 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_pol_Rbc25 PF08292.12 EEQ39251.1 - 5.5e-47 159.2 1.4 1.1e-46 158.2 1.4 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EEQ39251.1 - 1.5e-16 60.5 0.0 2.3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EEQ39251.1 - 0.0007 19.9 0.0 0.0021 18.4 0.0 1.9 2 1 0 2 2 2 1 S1 RNA binding domain RRM_1 PF00076.22 EEQ39252.1 - 7.9e-21 73.7 0.1 1e-20 73.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Papilin_u7 PF16626.5 EEQ39253.1 - 0.068 13.8 0.1 0.18 12.4 0.0 1.7 2 0 0 2 2 2 0 Linking region between Kunitz_BPTI and I-set on papilin Ion_trans PF00520.31 EEQ39253.1 - 0.12 11.6 0.1 0.18 11.0 0.1 1.3 1 0 0 1 1 1 0 Ion transport protein DUF3995 PF13160.6 EEQ39253.1 - 0.14 12.5 0.8 3.1 8.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) HLH PF00010.26 EEQ39256.1 - 6.4e-11 42.0 0.0 1.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RTC4 PF14474.6 EEQ39257.1 - 2.7e-30 105.0 0.0 4.9e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain Pterin_bind PF00809.22 EEQ39258.1 - 4.5e-68 229.6 1.7 4.9e-66 222.9 1.7 2.2 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 EEQ39258.1 - 3e-35 121.1 0.0 5e-18 65.7 0.0 2.6 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 EEQ39258.1 - 6.7e-29 100.7 0.0 1.7e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) F420_oxidored PF03807.17 EEQ39258.1 - 1 10.0 3.5 4.2 8.0 0.1 3.0 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent zf-CCHC PF00098.23 EEQ39259.1 - 1.6e-45 151.2 60.1 9e-08 31.9 3.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EEQ39259.1 - 3.4e-13 49.1 39.2 0.064 13.0 0.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 EEQ39259.1 - 8.1e-05 22.5 48.6 0.031 14.2 0.5 7.0 2 2 4 6 6 6 5 Zinc knuckle zf-CCHC_6 PF15288.6 EEQ39259.1 - 0.027 14.3 1.9 0.027 14.3 1.9 6.9 6 1 1 7 7 7 0 Zinc knuckle zf-CCHC_5 PF14787.6 EEQ39259.1 - 0.69 9.7 40.1 0.23 11.2 1.1 6.6 5 2 2 7 7 7 0 GAG-polyprotein viral zinc-finger Pro_isomerase PF00160.21 EEQ39260.1 - 6.4e-13 49.3 0.1 9.9e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EEQ39260.1 - 1.8e-08 34.1 2.0 5.2e-08 32.6 0.1 2.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Aminotran_5 PF00266.19 EEQ39261.1 - 6e-18 64.9 0.0 7.4e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ39261.1 - 0.00021 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Hema_stalk PF08720.10 EEQ39261.1 - 0.15 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Influenza C hemagglutinin stalk adh_short_C2 PF13561.6 EEQ39262.1 - 6.2e-62 209.2 0.1 7.2e-62 209.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ39262.1 - 3.6e-42 144.1 0.8 4.2e-42 143.8 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ39262.1 - 1.6e-13 51.0 0.2 2.5e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ39262.1 - 1.7e-05 24.4 0.2 0.0004 19.9 0.2 2.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ39262.1 - 0.00018 20.7 0.1 0.00028 20.0 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EEQ39262.1 - 0.0002 21.6 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EEQ39262.1 - 0.00068 19.1 0.2 0.0018 17.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EEQ39262.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EEQ39262.1 - 0.018 14.1 0.1 0.037 13.1 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain F420_oxidored PF03807.17 EEQ39262.1 - 0.027 15.1 0.0 0.051 14.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 EEQ39262.1 - 0.038 13.6 0.1 0.071 12.7 0.1 1.4 1 1 0 1 1 1 0 NmrA-like family PALP PF00291.25 EEQ39262.1 - 0.042 13.3 0.1 0.057 12.8 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Glyco_hydro_63 PF03200.16 EEQ39263.1 - 3e-08 32.9 7.2 2.7e-06 26.4 0.4 3.7 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain V-SNARE PF05008.15 EEQ39264.1 - 5.8e-22 77.9 7.6 5.8e-22 77.9 7.6 2.8 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EEQ39264.1 - 1.4e-17 63.7 4.8 1.4e-17 63.7 4.8 2.9 3 1 1 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus Use1 PF09753.9 EEQ39264.1 - 0.00077 19.3 9.4 0.0013 18.5 9.4 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 MMPL PF03176.15 EEQ39264.1 - 0.033 13.1 1.3 0.045 12.7 1.3 1.1 1 0 0 1 1 1 0 MMPL family PKK PF12474.8 EEQ39264.1 - 0.038 14.1 10.3 0.057 13.6 10.3 1.3 1 0 0 1 1 1 0 Polo kinase kinase DUF4407 PF14362.6 EEQ39264.1 - 0.051 12.9 12.9 0.1 11.9 12.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YidC_periplas PF14849.6 EEQ39264.1 - 0.12 12.3 0.3 0.19 11.6 0.3 1.2 1 0 0 1 1 1 0 YidC periplasmic domain YqjK PF13997.6 EEQ39264.1 - 0.29 11.4 0.0 0.29 11.4 0.0 3.6 4 0 0 4 4 4 0 YqjK-like protein Sec20 PF03908.13 EEQ39264.1 - 0.49 10.3 8.4 0.12 12.3 0.9 2.8 1 1 1 3 3 3 0 Sec20 PACT_coil_coil PF10495.9 EEQ39264.1 - 0.56 10.8 3.5 2.5 8.7 3.5 2.3 1 1 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fib_alpha PF08702.10 EEQ39264.1 - 1.1 9.4 8.4 0.76 10.0 1.1 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fusion_gly PF00523.18 EEQ39264.1 - 3.4 5.8 8.7 0.51 8.5 2.2 2.3 1 1 1 3 3 3 0 Fusion glycoprotein F0 Enkurin PF13864.6 EEQ39264.1 - 4 7.9 8.2 11 6.6 2.2 2.7 1 1 1 2 2 2 0 Calmodulin-binding DASH_Dad1 PF08649.10 EEQ39264.1 - 7.1 6.9 6.2 1.6 9.0 0.4 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad1 Exonuc_VII_L PF02601.15 EEQ39264.1 - 9.2 5.7 17.9 71 2.8 17.9 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit Fer2 PF00111.27 EEQ39265.1 - 5.4e-13 48.7 1.1 7.4e-13 48.3 1.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Microtub_bd PF16796.5 EEQ39266.1 - 6.4e-06 26.2 0.1 6.4e-06 26.2 0.1 3.7 2 2 1 3 3 3 2 Microtubule binding CEP209_CC5 PF16574.5 EEQ39266.1 - 7.3e-05 22.9 12.0 7.3e-05 22.9 12.0 4.3 1 1 2 3 3 3 1 Coiled-coil region of centrosome protein CE290 G2BR PF18442.1 EEQ39266.1 - 0.54 9.9 3.8 7.3 6.3 0.6 2.9 2 0 0 2 2 2 0 E3 gp78 Ube2g2-binding region (G2BR) Filament PF00038.21 EEQ39266.1 - 2.6 7.5 51.6 7.5 6.0 16.7 2.4 1 1 1 2 2 2 0 Intermediate filament protein ATG16 PF08614.11 EEQ39266.1 - 3.9 7.7 57.9 6.4 6.9 20.5 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF4996 PF16387.5 EEQ39266.1 - 5.2 7.6 6.4 0.92 10.0 1.5 2.4 2 1 1 3 3 3 0 Domain of unknown function DUF1664 PF07889.12 EEQ39266.1 - 6 6.9 30.0 2.7 8.0 7.4 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SAGA-Tad1 PF12767.7 EEQ39267.1 - 3.1e-57 194.0 6.3 3.1e-57 194.0 6.3 2.1 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 EEQ39267.1 - 4.8e-07 29.8 0.1 1.3e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family MFS_1 PF07690.16 EEQ39268.1 - 6.8e-36 123.9 59.0 4.9e-34 117.8 55.5 2.9 1 1 0 2 2 2 2 Major Facilitator Superfamily Sybindin PF04099.12 EEQ39269.1 - 9.7e-18 64.5 0.1 1.1e-17 64.3 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family RVT_2 PF07727.14 EEQ39270.1 - 2.3e-84 282.8 0.5 3.7e-84 282.2 0.5 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EEQ39270.1 - 1.8e-21 76.5 0.1 3.6e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EEQ39270.1 - 0.00048 19.8 0.3 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 EEQ39270.1 - 0.018 14.9 0.0 0.059 13.2 0.0 1.9 1 0 0 1 1 1 0 GAG-pre-integrase domain DUF5314 PF17241.2 EEQ39270.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Methyltransf_16 PF10294.9 EEQ39271.1 - 1.4e-15 57.5 0.0 6.3e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase MTS PF05175.14 EEQ39271.1 - 0.0051 16.4 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EEQ39271.1 - 0.029 15.1 0.2 0.088 13.5 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ39271.1 - 0.15 12.8 0.4 0.69 10.7 0.2 2.2 2 1 0 2 2 2 0 Methyltransferase domain Allantoicase PF03561.15 EEQ39272.1 - 1.2e-92 307.5 0.2 2.7e-45 153.9 0.1 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 EEQ39272.1 - 0.0014 18.7 0.1 0.003 17.7 0.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain WcbI PF18588.1 EEQ39272.1 - 0.1 12.2 0.0 0.33 10.5 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis enzyme WcbI CENP-H PF05837.12 EEQ39273.1 - 0.4 11.1 23.3 1.5 9.3 1.8 3.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Spc7 PF08317.11 EEQ39273.1 - 1.1 8.1 24.3 0.21 10.4 15.4 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein JIP_LZII PF16471.5 EEQ39273.1 - 1.9 8.7 11.6 1.7 8.9 0.3 4.0 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 EEQ39273.1 - 5.7 6.2 8.5 13 5.1 8.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HTH_Tnp_Tc5 PF03221.16 EEQ39274.1 - 9.1e-16 57.7 0.0 2.1e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DUF2959 PF11172.8 EEQ39274.1 - 0.03 14.5 2.3 0.059 13.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) DUF4817 PF16087.5 EEQ39274.1 - 0.032 14.1 0.2 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) DegS PF05384.11 EEQ39274.1 - 0.34 10.4 5.9 0.53 9.8 5.9 1.2 1 0 0 1 1 1 0 Sensor protein DegS UB2H PF14814.6 EEQ39274.1 - 0.58 10.2 2.8 0.83 9.7 0.7 2.1 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain DnaJ_C PF01556.18 EEQ39275.1 - 2.5e-36 125.0 0.1 3.5e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ39275.1 - 9.5e-25 86.5 4.2 1.7e-24 85.7 4.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEQ39275.1 - 2.9e-13 50.0 18.3 5.5e-13 49.1 18.3 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EEQ39275.1 - 0.0093 15.9 9.1 0.6 10.1 0.7 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein DUF1356 PF07092.12 EEQ39275.1 - 0.024 13.9 3.9 0.39 10.0 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) HypA PF01155.19 EEQ39275.1 - 0.03 14.3 7.3 1.8 8.6 1.6 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 EEQ39275.1 - 0.77 9.9 5.5 1.1 9.5 0.3 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF4705 PF15788.5 EEQ39276.1 - 0.11 12.7 8.1 0.12 12.6 3.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4705) AA_permease PF00324.21 EEQ39277.1 - 1.1e-116 390.3 36.9 1.2e-116 390.1 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ39277.1 - 3.7e-37 128.2 38.5 4.5e-37 127.9 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease DX PF01666.17 EEQ39279.1 - 0.081 13.4 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 DX module RALF PF05498.11 EEQ39279.1 - 0.12 13.3 1.3 0.31 12.0 0.2 2.3 3 0 0 3 3 3 0 Rapid ALkalinization Factor (RALF) DUF4978 PF16349.5 EEQ39282.1 - 0.013 15.2 0.1 0.035 13.8 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4978) HtaA PF04213.13 EEQ39282.1 - 0.13 12.7 0.1 0.64 10.5 0.1 2.2 2 0 0 2 2 2 0 Htaa Na_Ca_ex_C PF16494.5 EEQ39282.1 - 0.89 10.0 4.6 1.9 9.0 0.3 3.1 3 0 0 3 3 3 0 C-terminal extension of sodium/calcium exchanger domain RNA_polI_A14 PF08203.11 EEQ39283.1 - 1.3e-22 80.3 0.0 1.3e-22 80.3 0.0 2.9 2 1 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 CDC45 PF02724.14 EEQ39283.1 - 8.7e-05 21.0 34.9 9.3e-05 20.9 34.9 1.2 1 0 0 1 1 1 1 CDC45-like protein CCSAP PF15748.5 EEQ39283.1 - 0.16 12.1 33.0 0.22 11.6 33.0 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SDA1 PF05285.12 EEQ39283.1 - 0.53 9.7 59.5 0.69 9.3 59.5 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EEQ39283.1 - 7.9 4.5 59.6 9.3 4.3 59.6 1.1 1 0 0 1 1 1 0 Nop14-like family SMC_N PF02463.19 EEQ39284.1 - 1.2e-61 207.9 61.7 1.1e-31 110.0 23.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EEQ39284.1 - 3.3e-22 79.0 0.0 1.4e-21 77.0 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EEQ39284.1 - 3.3e-10 40.3 12.3 5.4e-05 23.2 0.0 4.2 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EEQ39284.1 - 8.1e-06 25.8 30.7 8.1e-06 25.8 30.7 4.5 2 2 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EEQ39284.1 - 0.0001 22.0 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 EEQ39284.1 - 5.6 5.8 143.2 0.041 12.8 22.5 6.9 2 2 5 7 7 7 0 Spc7 kinetochore protein Dus PF01207.17 EEQ39285.1 - 5.7e-79 265.4 0.0 6.8e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) MR_MLE_C PF13378.6 EEQ39285.1 - 8.4e-06 25.5 0.7 7.9e-05 22.3 0.7 2.2 1 1 0 1 1 1 1 Enolase C-terminal domain-like TMP-TENI PF02581.17 EEQ39285.1 - 0.00019 20.8 0.1 0.00083 18.7 0.0 1.9 1 1 1 2 2 2 1 Thiamine monophosphate synthase Resolvase PF00239.21 EEQ39285.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.5 1 0 0 1 1 1 0 Resolvase, N terminal domain Bromodomain PF00439.25 EEQ39286.1 - 6.9e-43 144.6 1.3 1.7e-21 76.1 0.2 2.7 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EEQ39286.1 - 2e-14 53.5 2.6 6.9e-14 51.8 2.6 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation MRPL52 PF18699.1 EEQ39286.1 - 0.06 13.5 4.0 0.17 12.1 4.0 1.8 1 0 0 1 1 1 0 Mitoribosomal protein mL52 BRE1 PF08647.11 EEQ39287.1 - 2.2e-23 82.2 8.4 2.2e-23 82.2 8.4 6.8 5 2 1 6 6 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EEQ39287.1 - 3.8e-09 36.2 6.9 6e-09 35.6 6.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ39287.1 - 5.6e-09 35.7 7.4 9.5e-09 35.0 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ39287.1 - 4.1e-08 33.1 8.8 6.8e-08 32.4 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ39287.1 - 5.5e-08 32.5 5.9 9.2e-08 31.8 5.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EEQ39287.1 - 1.1e-06 28.4 7.6 2e-06 27.6 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ39287.1 - 8.4e-06 26.0 8.3 1.4e-05 25.3 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EEQ39287.1 - 1.6e-05 24.8 6.1 3.4e-05 23.8 6.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EEQ39287.1 - 0.0043 17.3 5.5 0.0092 16.2 5.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EEQ39287.1 - 0.0057 16.8 5.5 0.012 15.8 5.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EEQ39287.1 - 0.015 15.2 3.4 0.035 14.0 3.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Fungal_TACC PF12709.7 EEQ39287.1 - 0.024 15.1 3.9 0.024 15.1 3.9 7.4 4 2 4 8 8 7 0 Fungal Transforming acidic coiled-coil (TACC) proteins zf-C2H2 PF00096.26 EEQ39287.1 - 0.026 14.9 2.4 0.049 14.1 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ39287.1 - 0.1 13.5 2.0 3.8 8.6 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1272 PF06906.11 EEQ39287.1 - 0.27 11.4 4.6 0.59 10.3 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_10 PF16685.5 EEQ39287.1 - 0.47 10.6 5.1 1 9.5 5.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EEQ39287.1 - 0.7 9.7 6.2 1.4 8.8 6.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EEQ39287.1 - 1.1 8.9 5.9 1.9 8.1 5.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C2H2_jaz PF12171.8 EEQ39287.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.0 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EEQ39287.1 - 1.9 8.6 6.3 3.6 7.7 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger HypA PF01155.19 EEQ39287.1 - 2.4 8.2 8.0 20 5.2 7.4 2.8 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Filament PF00038.21 EEQ39287.1 - 3.7 7.0 68.2 0.82 9.2 15.0 3.5 2 1 1 3 3 3 0 Intermediate filament protein FYVE PF01363.21 EEQ39287.1 - 4.8 7.4 9.6 24 5.1 9.6 2.1 1 1 0 1 1 1 0 FYVE zinc finger HSBP1 PF06825.12 EEQ39287.1 - 8.3 6.4 0.0 8.3 6.4 0.0 4.6 5 0 0 5 5 5 0 Heat shock factor binding protein 1 Glyco_hydro_31 PF01055.26 EEQ39288.1 - 2.4e-132 442.3 0.8 3.5e-132 441.7 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EEQ39288.1 - 1.2e-24 86.4 0.3 3.5e-23 81.7 0.1 2.6 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EEQ39288.1 - 4.6e-08 33.2 0.1 1.4e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF5583 PF17821.1 EEQ39289.1 - 0.044 13.7 0.2 0.084 12.8 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5583) HSF_DNA-bind PF00447.17 EEQ39290.1 - 1.5e-30 105.6 3.1 2.5e-30 105.0 3.1 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 EEQ39290.1 - 1.1e-26 93.2 0.4 2e-26 92.4 0.4 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Spermine_synth PF01564.17 EEQ39290.1 - 0.017 14.5 0.2 0.036 13.5 0.2 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase domain SRR1 PF07985.12 EEQ39291.1 - 2.1e-16 59.7 0.1 4e-16 58.8 0.1 1.5 1 0 0 1 1 1 1 SRR1 Pribosyltran_N PF13793.6 EEQ39292.1 - 5.3e-40 136.0 0.0 1.2e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EEQ39292.1 - 2.2e-39 135.4 1.8 6.7e-38 130.6 1.8 2.2 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EEQ39292.1 - 6.4e-07 29.0 0.3 5.7e-06 25.9 0.3 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain His_Phos_2 PF00328.22 EEQ39293.1 - 1.4e-136 455.8 0.1 1.9e-136 455.4 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EEQ39293.1 - 9.6e-37 125.0 0.0 2.3e-36 123.8 0.0 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EEQ39293.1 - 1e-05 25.2 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain DUF1729 PF08354.10 EEQ39294.1 - 2.7e-154 513.3 0.0 4.6e-154 512.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EEQ39294.1 - 8.6e-95 317.9 0.0 7.3e-93 311.6 0.0 3.4 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 EEQ39294.1 - 1e-49 168.1 0.0 2.1e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 EEQ39294.1 - 3.2e-42 144.9 0.0 5.7e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EEQ39294.1 - 1.7e-38 130.9 0.0 3.7e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 EEQ39294.1 - 4.3e-30 104.4 0.0 1.2e-29 102.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EEQ39294.1 - 3.2e-16 59.7 0.1 3.9e-15 56.2 0.0 2.8 4 0 0 4 4 4 1 N-terminal half of MaoC dehydratase DUF438 PF04282.13 EEQ39294.1 - 0.055 13.4 0.8 1.7 8.7 0.2 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF438) Gp_dh_C PF02800.20 EEQ39296.1 - 2.7e-33 114.8 0.0 4.6e-33 114.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EEQ39296.1 - 4.3e-05 23.8 0.0 9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Endonuclease_NS PF01223.23 EEQ39297.1 - 1.9e-64 217.6 0.0 2.2e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease OPT PF03169.15 EEQ39298.1 - 3.4e-149 498.3 37.8 3.9e-149 498.1 37.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Neurensin PF14927.6 EEQ39298.1 - 0.05 13.3 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Neurensin Sod_Cu PF00080.20 EEQ39299.1 - 2.2e-15 57.1 0.0 3.2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Abhydrolase_1 PF00561.20 EEQ39300.1 - 7.3e-25 88.1 0.8 9.1e-25 87.8 0.8 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EEQ39300.1 - 1.2e-19 69.6 0.1 2.2e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 EEQ39300.1 - 0.00022 20.6 0.0 0.0012 18.2 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EEQ39300.1 - 0.00049 20.0 0.1 0.22 11.3 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.13 EEQ39300.1 - 0.02 14.6 0.2 2.1 8.0 0.1 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) zf-C2H2 PF00096.26 EEQ39301.1 - 0.26 11.8 5.9 0.25 11.9 1.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 EEQ39302.1 - 2.4e-05 24.5 5.0 0.058 13.9 0.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 EEQ39302.1 - 0.0092 16.3 2.1 0.038 14.3 2.2 2.0 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EEQ39302.1 - 0.2 12.6 0.2 0.2 12.6 0.2 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf_ZIC PF18366.1 EEQ39302.1 - 0.2 11.8 1.0 0.47 10.6 0.1 2.0 2 0 0 2 2 2 0 Zic proteins zinc finger domain CRC_subunit PF08624.10 EEQ39303.1 - 1.2e-48 165.0 0.1 2.2e-48 164.1 0.1 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Peptidase_M41 PF01434.18 EEQ39304.1 - 1.4e-66 224.0 0.0 3.1e-66 222.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EEQ39304.1 - 8.5e-43 146.0 0.3 9.1e-42 142.6 0.0 2.7 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ39304.1 - 4.7e-12 45.5 0.1 1.3e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 EEQ39304.1 - 3.5e-05 24.1 0.1 0.00012 22.4 0.1 1.9 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 EEQ39304.1 - 0.0034 17.4 0.6 0.095 12.7 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ39304.1 - 0.0041 16.9 0.0 0.014 15.2 0.0 1.9 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EEQ39304.1 - 0.0042 16.3 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_17 PF13207.6 EEQ39304.1 - 0.007 16.8 0.0 0.026 14.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EEQ39304.1 - 0.0084 16.2 1.6 0.024 14.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EEQ39304.1 - 0.0086 16.3 4.2 1 9.7 0.2 3.9 3 1 1 4 4 4 1 AAA domain PRESAN PF09687.10 EEQ39304.1 - 0.011 16.3 0.3 0.11 13.0 0.2 2.5 2 0 0 2 2 2 0 Plasmodium RESA N-terminal IstB_IS21 PF01695.17 EEQ39304.1 - 0.013 15.2 0.0 0.079 12.7 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 EEQ39304.1 - 0.014 15.8 0.2 0.1 13.0 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 EEQ39304.1 - 0.12 12.3 0.4 0.66 10.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4164 PF13747.6 EEQ39304.1 - 3.1 8.2 6.6 5.1 7.5 2.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) AAA_11 PF13086.6 EEQ39304.1 - 6.1 6.6 6.0 9.1 6.0 0.1 3.0 3 0 0 3 3 3 0 AAA domain LCAT PF02450.15 EEQ39305.1 - 2.9e-07 30.0 0.0 4.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EEQ39305.1 - 5.6e-07 30.4 0.0 2e-06 28.6 0.0 1.8 1 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ39305.1 - 5.4e-06 25.9 0.0 9.5e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ39305.1 - 0.00021 21.0 0.0 0.0059 16.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EEQ39305.1 - 0.00031 20.4 0.0 0.00057 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF900 PF05990.12 EEQ39305.1 - 0.0016 18.0 0.0 0.0026 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 EEQ39305.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Esterase PF00756.20 EEQ39305.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DnaJ PF00226.31 EEQ39306.1 - 2.4e-17 62.8 0.0 3.2e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.13 EEQ39306.1 - 1.6e-12 47.0 0.0 2.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 CSL zinc finger zf-NADH-PPase PF09297.11 EEQ39306.1 - 8 6.2 6.5 0.56 9.9 0.2 2.2 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain RNA_pol_I_A49 PF06870.12 EEQ39307.1 - 1.5e-109 366.4 0.0 1.7e-109 366.2 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor NAP PF00956.18 EEQ39308.1 - 3.3e-14 52.7 5.0 5.3e-14 52.0 5.0 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) FAD_binding_3 PF01494.19 EEQ39309.1 - 9.3e-20 71.2 6.9 9.7e-18 64.5 6.9 3.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EEQ39309.1 - 6.8e-07 28.7 3.7 0.0045 16.1 0.0 3.7 3 1 1 4 4 4 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 EEQ39309.1 - 8.6e-05 22.6 0.7 0.00074 19.5 0.0 2.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 EEQ39309.1 - 0.00012 21.8 3.6 0.012 15.2 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ39309.1 - 0.00044 19.6 1.5 0.0033 16.7 1.3 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EEQ39309.1 - 0.0012 17.8 0.0 0.12 11.1 0.0 2.7 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.10 EEQ39309.1 - 0.0091 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 EEQ39309.1 - 0.034 13.4 0.3 0.096 11.9 0.0 1.9 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.6 EEQ39309.1 - 0.035 14.4 0.0 0.089 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EEQ39309.1 - 0.039 14.5 0.2 5.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ39309.1 - 0.11 11.7 1.7 0.57 9.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF676 PF05057.14 EEQ39310.1 - 4.7e-06 26.3 0.0 8.6e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EEQ39310.1 - 2.5e-05 24.1 0.0 5.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EEQ39310.1 - 3.8e-05 23.7 0.0 6.9e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EEQ39310.1 - 4.9e-05 22.8 0.0 0.00049 19.5 0.0 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 EEQ39310.1 - 0.00052 19.3 0.0 0.00074 18.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 EEQ39310.1 - 0.0029 18.3 0.0 0.0056 17.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ39310.1 - 0.01 15.5 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EEQ39310.1 - 0.021 14.7 0.0 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.8 EEQ39310.1 - 0.037 13.3 0.0 0.096 11.9 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Aldedh PF00171.22 EEQ39311.1 - 4.4e-106 355.1 0.1 5.5e-106 354.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EEQ39311.1 - 0.00035 20.1 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) LPD7 PF18821.1 EEQ39311.1 - 0.056 13.6 0.2 15 5.8 0.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 7 Ribosomal_L13 PF00572.18 EEQ39312.1 - 5.3e-12 46.1 0.0 4.9e-10 39.7 0.0 2.5 1 1 0 1 1 1 1 Ribosomal protein L13 HMGL-like PF00682.19 EEQ39313.1 - 4.4e-83 278.9 0.0 6.1e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 EEQ39313.1 - 1.1e-27 96.5 0.3 2.4e-27 95.5 0.3 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain RRM_1 PF00076.22 EEQ39314.1 - 1.7e-43 146.3 0.0 1.5e-20 72.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ39314.1 - 0.00067 19.2 0.0 0.11 12.1 0.0 2.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ39314.1 - 0.0043 17.1 0.0 5.5 7.2 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif DbpA PF03880.15 EEQ39314.1 - 0.089 12.8 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 DbpA RNA binding domain SPOR PF05036.13 EEQ39314.1 - 0.13 12.7 0.0 9.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Sporulation related domain FAM196 PF15265.6 EEQ39314.1 - 4.1 6.8 43.6 5.3 6.4 43.6 1.1 1 0 0 1 1 1 0 FAM196 family Utp14 PF04615.13 EEQ39314.1 - 4.4 5.8 45.5 6.7 5.2 45.5 1.4 1 0 0 1 1 1 0 Utp14 protein Prothymosin PF03247.14 EEQ39314.1 - 7.2 7.1 43.1 0.74 10.3 24.5 2.3 1 1 1 2 2 2 0 Prothymosin/parathymosin family BUD22 PF09073.10 EEQ39315.1 - 0.0025 17.3 54.8 0.0036 16.7 54.8 1.4 1 0 0 1 1 1 1 BUD22 ALMT PF11744.8 EEQ39315.1 - 0.38 9.5 15.7 0.45 9.3 15.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Prothymosin PF03247.14 EEQ39315.1 - 4.2 7.9 70.9 1.1 9.8 33.9 2.5 2 0 0 2 2 2 0 Prothymosin/parathymosin family Arrestin_N PF00339.29 EEQ39317.1 - 1.8e-15 57.3 0.0 4.1e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EEQ39317.1 - 2.6e-11 44.1 0.2 5.6e-09 36.5 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain TMEM51 PF15345.6 EEQ39317.1 - 0.11 12.3 3.3 0.27 11.0 3.3 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 Kelch_5 PF13854.6 EEQ39318.1 - 1.1e-28 98.7 18.2 9e-07 28.8 0.2 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EEQ39318.1 - 3.5e-26 91.0 10.0 2.2e-06 27.6 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EEQ39318.1 - 2.3e-21 75.3 12.1 4.9e-08 33.0 0.2 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EEQ39318.1 - 9.9e-21 73.1 5.9 1.7e-10 40.3 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EEQ39318.1 - 4.3e-19 68.3 7.0 3e-05 24.2 0.2 5.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EEQ39318.1 - 2.4e-17 62.1 9.1 1.9e-07 30.8 0.1 6.6 6 0 0 6 6 6 3 Kelch motif Fib_alpha PF08702.10 EEQ39318.1 - 0.0036 17.5 2.2 0.0036 17.5 2.2 4.8 2 1 4 6 6 6 1 Fibrinogen alpha/beta chain family Metal_resist PF13801.6 EEQ39318.1 - 0.0065 16.7 5.9 0.97 9.6 2.9 3.0 3 0 0 3 3 3 2 Heavy-metal resistance UPF0242 PF06785.11 EEQ39318.1 - 0.0085 16.2 1.3 0.0085 16.2 1.3 4.6 3 1 2 5 5 5 1 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 EEQ39318.1 - 1.1 7.7 5.6 2.4 6.6 5.6 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family ATG16 PF08614.11 EEQ39318.1 - 5.1 7.3 51.9 0.26 11.5 4.7 4.5 1 1 1 3 3 2 0 Autophagy protein 16 (ATG16) Vps53_N PF04100.12 EEQ39319.1 - 1.8e-69 234.6 16.8 1.8e-69 234.6 16.8 1.8 2 0 0 2 2 2 1 Vps53-like, N-terminal VPS53_C PF16854.5 EEQ39319.1 - 1.1e-05 25.4 8.3 1.4e-05 25.1 2.7 3.2 2 1 0 2 2 2 1 Vacuolar protein sorting-associated protein 53 C-terminus COG2 PF06148.11 EEQ39319.1 - 0.0053 16.9 1.3 0.02 15.0 1.3 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Cloacin_immun PF03513.14 EEQ39319.1 - 0.17 12.3 1.5 0.57 10.6 0.1 2.6 3 0 0 3 3 3 0 Cloacin immunity protein LPP PF04728.13 EEQ39319.1 - 0.35 11.3 2.7 12 6.3 0.2 3.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper PRAI PF00697.22 EEQ39320.1 - 1.1e-45 155.8 0.0 1.2e-40 139.4 0.0 2.1 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Cpn60_TCP1 PF00118.24 EEQ39321.1 - 5.8e-149 496.9 9.2 6.6e-149 496.7 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 EEQ39321.1 - 0.012 16.0 0.0 0.052 13.9 0.0 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor bZIP_1 PF00170.21 EEQ39322.1 - 1.1e-09 38.2 11.0 2e-09 37.4 11.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ39322.1 - 0.00072 19.6 10.7 0.002 18.1 10.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper TROVE PF05731.11 EEQ39322.1 - 0.023 13.8 0.0 0.024 13.7 0.0 1.1 1 0 0 1 1 1 0 TROVE domain bZIP_Maf PF03131.17 EEQ39322.1 - 0.081 13.4 9.8 0.2 12.2 9.8 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor MIP-T3_C PF17749.1 EEQ39322.1 - 0.83 9.6 5.1 0.38 10.7 2.7 1.6 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF1043 PF06295.12 EEQ39322.1 - 2 8.5 6.0 7.2 6.6 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Ndc1_Nup PF09531.10 EEQ39322.1 - 6.8 5.2 8.8 9.6 4.8 8.8 1.3 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pex24p PF06398.11 EEQ39324.1 - 0.00029 20.0 0.5 0.00032 19.8 0.5 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin CDP-OH_P_transf PF01066.21 EEQ39325.1 - 8.2e-17 61.7 0.9 8.2e-17 61.7 0.9 2.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MDD_C PF18376.1 EEQ39326.1 - 1.3e-70 236.9 0.0 1.9e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EEQ39326.1 - 5.3e-10 39.4 1.8 1.2e-09 38.3 1.5 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain WD40 PF00400.32 EEQ39327.1 - 2.7e-57 189.4 17.0 2.1e-10 41.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 EEQ39327.1 - 4.6e-30 103.8 9.3 4.6e-30 103.8 9.3 1.9 2 0 0 2 2 2 1 Tup N-terminal ANAPC4_WD40 PF12894.7 EEQ39327.1 - 1.5e-17 63.6 0.1 0.0003 21.0 0.0 5.8 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ39327.1 - 7.3e-08 31.5 1.1 0.29 9.7 0.0 4.4 2 1 2 4 4 4 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EEQ39327.1 - 4.4e-07 29.5 0.1 0.42 9.9 0.0 5.6 4 1 1 5 5 5 1 WD40-like domain Ge1_WD40 PF16529.5 EEQ39327.1 - 1e-05 24.7 0.1 1.6 7.6 0.0 4.2 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EEQ39327.1 - 0.0091 15.9 0.0 25 5.0 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ret2_MD PF18528.1 EEQ39327.1 - 0.049 14.0 0.0 11 6.4 0.0 3.5 1 1 2 3 3 3 0 RNA editing 3' terminal uridylyl transferase 2 middle domain Nbas_N PF15492.6 EEQ39327.1 - 0.083 12.2 0.4 28 3.9 0.0 3.7 1 1 4 5 5 5 0 Neuroblastoma-amplified sequence, N terminal TFIIA PF03153.13 EEQ39327.1 - 2 8.3 39.4 18 5.1 39.4 2.0 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit COX16 PF14138.6 EEQ39328.1 - 8e-26 90.4 0.5 1.2e-25 89.8 0.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 EEQ39328.1 - 0.17 12.4 0.2 0.82 10.2 0.0 1.9 1 1 1 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II zf-LYAR PF08790.11 EEQ39329.1 - 9e-16 57.5 6.3 9e-16 57.5 6.3 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 EEQ39329.1 - 0.013 15.1 0.6 5.8 6.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF2052 PF09747.9 EEQ39329.1 - 0.04 14.0 9.3 0.052 13.7 9.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TraV PF09676.10 EEQ39329.1 - 0.081 13.9 8.4 0.13 13.3 8.4 1.4 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) LIM PF00412.22 EEQ39329.1 - 0.19 12.0 7.8 0.37 11.0 7.8 1.5 1 0 0 1 1 1 0 LIM domain XRN_M PF17846.1 EEQ39329.1 - 0.24 10.3 8.8 0.28 10.1 8.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Trypan_PARP PF05887.11 EEQ39329.1 - 0.3 11.1 3.6 0.45 10.5 3.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-C2H2_4 PF13894.6 EEQ39329.1 - 0.55 11.2 8.3 6.9 7.8 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Zip PF02535.22 EEQ39329.1 - 1.1 8.4 4.4 1.2 8.3 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.14 EEQ39329.1 - 1.4 7.1 10.7 1.6 6.9 10.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.16 EEQ39329.1 - 1.7 8.6 5.1 1.9 8.5 5.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EEQ39329.1 - 3.9 6.1 8.2 4.5 5.9 8.2 1.1 1 0 0 1 1 1 0 Presenilin Csm1 PF12539.8 EEQ39330.1 - 5.2e-21 75.1 0.2 9.7e-21 74.2 0.2 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Syntaxin-6_N PF09177.11 EEQ39330.1 - 0.04 14.5 2.5 2.5 8.7 1.2 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HIP1_clath_bdg PF16515.5 EEQ39330.1 - 0.052 14.2 6.7 0.058 14.0 1.5 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mlf1IP PF10248.9 EEQ39330.1 - 0.079 12.9 1.6 0.18 11.8 0.7 2.0 1 1 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein CTD_bind PF04818.13 EEQ39331.1 - 5.8e-20 71.9 0.0 2.1e-19 70.1 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF1759 PF03564.15 EEQ39331.1 - 0.024 14.6 0.3 0.059 13.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Prefoldin_3 PF13758.6 EEQ39331.1 - 0.034 14.2 2.0 0.11 12.6 1.0 2.4 2 0 0 2 2 2 0 Prefoldin subunit DUF3246 PF11596.8 EEQ39331.1 - 0.077 12.4 11.4 0.13 11.6 11.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF2408 PF10303.9 EEQ39331.1 - 1.5 9.4 0.0 1.5 9.4 0.0 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) PI3K_P85_iSH2 PF16454.5 EEQ39331.1 - 2.5 7.7 9.4 0.32 10.6 1.1 3.2 2 1 1 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spectrin PF00435.21 EEQ39331.1 - 4 8.0 7.4 2.9 8.4 0.2 3.2 3 0 0 3 3 3 0 Spectrin repeat Zn_clus PF00172.18 EEQ39332.1 - 1.4e-05 25.1 13.3 1.4e-05 25.1 13.3 2.0 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IL1_propep PF02394.16 EEQ39332.1 - 0.73 10.8 3.5 0.37 11.7 0.6 2.0 2 0 0 2 2 2 0 Interleukin-1 propeptide UvrD-helicase PF00580.21 EEQ39333.1 - 4.1e-28 98.8 0.0 6.4e-14 52.2 0.1 2.4 1 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EEQ39333.1 - 5.3e-23 82.0 0.1 3.8e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 EEQ39333.1 - 6.6e-14 52.0 0.0 1.4e-10 41.1 0.0 3.1 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EEQ39333.1 - 7.9e-12 44.8 0.2 3e-11 43.0 0.2 2.0 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EEQ39333.1 - 6.3e-06 26.1 0.1 0.0026 17.5 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EEQ39333.1 - 0.0017 18.1 0.2 0.0059 16.3 0.2 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ39333.1 - 0.0019 18.0 0.6 0.0059 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EEQ39333.1 - 0.0022 17.6 0.0 0.096 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain MarR_2 PF12802.7 EEQ39333.1 - 0.0043 16.9 0.2 0.013 15.4 0.2 1.8 1 0 0 1 1 1 1 MarR family ResIII PF04851.15 EEQ39333.1 - 0.0079 16.2 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rrf2 PF02082.20 EEQ39333.1 - 0.043 14.2 0.0 0.24 11.8 0.0 2.3 1 0 0 1 1 1 0 Transcriptional regulator AAA_25 PF13481.6 EEQ39333.1 - 0.058 13.0 0.0 0.53 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain HTH_28 PF13518.6 EEQ39333.1 - 0.13 12.4 0.1 0.82 9.8 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Pex24p PF06398.11 EEQ39334.1 - 0.07 12.1 0.8 0.079 11.9 0.8 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Vps52 PF04129.12 EEQ39335.1 - 9.8e-69 232.4 12.7 8.9e-47 160.0 4.3 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family BESS PF02944.20 EEQ39335.1 - 0.18 11.7 1.1 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 BESS motif Rep_fac_C PF08542.11 EEQ39336.1 - 1e-23 83.5 0.1 1.1e-22 80.2 0.0 2.5 3 0 0 3 3 3 1 Replication factor C C-terminal domain AAA PF00004.29 EEQ39336.1 - 3.6e-12 46.8 0.0 6.8e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EEQ39336.1 - 1.1e-11 44.8 0.0 1.5e-09 37.9 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 EEQ39336.1 - 1.3e-06 28.5 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EEQ39336.1 - 2.3e-06 27.5 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ39336.1 - 7.4e-06 26.5 0.0 0.0015 18.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EEQ39336.1 - 3.3e-05 24.2 0.1 0.29 11.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EEQ39336.1 - 0.001 18.9 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EEQ39336.1 - 0.011 15.5 0.1 0.036 13.8 0.1 2.1 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 EEQ39336.1 - 0.015 15.6 0.0 0.037 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain DNA_pol3_delta PF06144.13 EEQ39336.1 - 0.025 14.4 0.2 0.04 13.7 0.2 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EEQ39336.1 - 0.029 13.8 0.0 0.44 9.9 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EEQ39336.1 - 0.033 14.5 0.1 0.26 11.6 0.1 2.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ39336.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 EEQ39336.1 - 0.051 13.0 0.0 8.6 5.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 EEQ39336.1 - 0.1 12.5 0.0 0.46 10.4 0.0 2.0 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 EEQ39336.1 - 0.11 11.5 0.0 2 7.3 0.0 2.3 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RNase_P_pop3 PF08228.11 EEQ39337.1 - 3.6e-18 66.1 0.0 1.4e-17 64.2 0.0 1.9 1 1 0 1 1 1 1 RNase P subunit Pop3 Ribosomal_60s PF00428.19 EEQ39337.1 - 0.0026 18.3 0.2 0.0061 17.1 0.2 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein gp32 PF08804.10 EEQ39337.1 - 0.016 15.2 1.0 0.024 14.7 0.0 1.7 1 1 1 2 2 2 0 gp32 DNA binding protein like Med30 PF11315.8 EEQ39338.1 - 0.0091 16.2 36.5 0.29 11.3 7.2 5.0 1 1 4 5 5 5 3 Mediator complex subunit 30 IFT57 PF10498.9 EEQ39338.1 - 0.012 14.6 22.5 0.06 12.3 12.4 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Laminin_II PF06009.12 EEQ39338.1 - 0.075 13.1 20.3 0.17 11.9 11.7 2.7 1 1 1 2 2 2 0 Laminin Domain II MCPsignal PF00015.21 EEQ39338.1 - 0.1 12.4 7.2 0.18 11.6 2.3 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EEQ39338.1 - 0.22 11.8 27.5 1e+04 -3.2 0.0 3.9 2 1 0 2 2 0 0 Bacterial protein of unknown function (DUF948) FPP PF05911.11 EEQ39338.1 - 0.22 9.7 11.7 0.3 9.2 11.7 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Lambda_CIII PF02061.16 EEQ39338.1 - 0.28 11.3 23.9 12 6.1 0.1 7.1 1 1 6 7 7 7 0 Lambda Phage CIII APG6_N PF17675.1 EEQ39338.1 - 0.42 11.1 19.9 4.4 7.8 17.7 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Sec20 PF03908.13 EEQ39338.1 - 0.46 10.4 24.2 0.22 11.5 7.7 3.6 1 1 2 3 3 3 0 Sec20 FlgN PF05130.12 EEQ39338.1 - 0.57 10.7 37.4 1.4 9.5 17.4 2.8 1 1 2 3 3 3 0 FlgN protein COG2 PF06148.11 EEQ39338.1 - 0.6 10.2 25.8 3.3 7.8 9.4 3.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GCN5L1 PF06320.13 EEQ39338.1 - 0.72 10.0 17.9 3.4e+03 -1.8 17.9 3.1 1 1 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) LXG PF04740.12 EEQ39338.1 - 0.84 9.3 18.1 0.93 9.2 9.9 2.2 1 1 1 2 2 2 0 LXG domain of WXG superfamily PMC2NT PF08066.12 EEQ39338.1 - 1.8 9.3 6.9 29 5.4 0.7 3.3 1 1 2 3 3 3 0 PMC2NT (NUC016) domain DUF2935 PF11155.8 EEQ39338.1 - 2.5 8.4 17.7 7.3e+03 -2.7 17.7 3.1 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) YojJ PF10372.9 EEQ39338.1 - 4 7.6 24.0 21 5.3 0.5 5.8 1 1 3 4 4 3 0 Bacterial membrane-spanning protein N-terminus EzrA PF06160.12 EEQ39338.1 - 4 5.5 15.9 10 4.1 15.7 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA BLOC1S3 PF15753.5 EEQ39338.1 - 4.6 7.3 26.3 0.44 10.7 6.6 3.1 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF148 PF02520.17 EEQ39338.1 - 4.7 7.4 18.7 18 5.5 0.9 3.7 1 1 1 2 2 2 0 Domain of unknown function DUF148 DUF5344 PF17279.2 EEQ39338.1 - 5.5 7.6 11.4 47 4.7 2.8 3.2 1 1 1 2 2 2 0 Family of unknown function (DUF5344) DUF4735 PF15882.5 EEQ39338.1 - 6.8 6.0 17.3 4.9 6.5 6.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) RNA_pol_Rpb1_R PF05001.13 EEQ39339.1 - 2.4e-33 112.7 344.1 0.00066 19.9 10.1 16.3 4 1 17 24 24 24 24 RNA polymerase Rpb1 C-terminal repeat RNA_pol_Rpb1_5 PF04998.17 EEQ39340.1 - 7.2e-109 363.3 0.1 1.3e-108 362.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EEQ39340.1 - 1.6e-101 339.7 0.1 4.4e-101 338.3 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EEQ39340.1 - 3.2e-77 258.4 0.0 9.7e-77 256.9 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EEQ39340.1 - 4.2e-65 219.2 0.1 1.3e-64 217.5 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 EEQ39340.1 - 1.9e-50 170.4 2.6 1.9e-50 170.4 2.6 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 EEQ39340.1 - 5.1e-50 169.5 0.3 1.4e-49 168.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EEQ39340.1 - 8.2e-38 128.7 0.1 2.3e-37 127.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 SLATT_4 PF18186.1 EEQ39340.1 - 0.037 13.7 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Alpha-amylase PF00128.24 EEQ39341.1 - 2.3e-72 244.4 2.3 2.9e-72 244.1 2.3 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 EEQ39341.1 - 5.3e-05 22.5 0.1 7e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase PF00128.24 EEQ39343.1 - 2e-17 63.8 0.2 1.4e-16 61.0 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EEQ39343.1 - 0.00014 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_42C PF08533.10 EEQ39343.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Beta-galactosidase C-terminal domain Na_Ca_ex PF01699.24 EEQ39344.1 - 1e-24 87.2 43.3 3.2e-18 66.1 14.2 4.3 5 1 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EEQ39344.1 - 1.8e-13 51.0 7.2 1.8e-13 51.0 7.2 4.0 5 0 0 5 5 5 1 Inner membrane component domain DER1 PF04511.15 EEQ39345.1 - 7.2e-24 84.8 14.3 2.5e-23 83.0 14.2 1.7 1 1 0 1 1 1 1 Der1-like family Peptidase_M56 PF05569.11 EEQ39345.1 - 0.77 8.9 4.0 5.1 6.2 4.0 1.9 1 1 0 1 1 1 0 BlaR1 peptidase M56 LSM PF01423.22 EEQ39346.1 - 9.6e-14 50.8 0.0 1.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEQ39346.1 - 0.066 13.4 0.0 0.093 12.9 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain XFP PF03894.15 EEQ39346.1 - 0.15 11.8 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Mitoc_mL59 PF18126.1 EEQ39347.1 - 2.8e-30 105.2 2.9 4.6e-30 104.6 2.9 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 FbpA PF05833.11 EEQ39347.1 - 0.036 12.8 4.7 0.05 12.4 4.7 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) ATP-synt_DE_N PF02823.16 EEQ39348.1 - 3.4e-20 71.7 0.0 5.7e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HisKA_2 PF07568.12 EEQ39348.1 - 0.071 13.2 0.2 3.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase Med2 PF11214.8 EEQ39349.1 - 2.8e-35 120.5 5.1 2.8e-35 120.5 5.1 3.8 2 1 1 3 3 2 1 Mediator complex subunit 2 rRNA_processing PF08524.11 EEQ39349.1 - 0.017 15.1 29.4 0.037 14.1 29.4 1.5 1 0 0 1 1 1 0 rRNA processing Asp-B-Hydro_N PF05279.11 EEQ39349.1 - 0.34 10.9 17.3 0.49 10.4 17.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FancD2 PF14631.6 EEQ39349.1 - 0.44 7.9 8.7 0.54 7.6 8.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease PV-1 PF06637.11 EEQ39349.1 - 0.47 9.2 13.4 0.6 8.9 13.4 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) CDC45 PF02724.14 EEQ39349.1 - 0.57 8.4 20.3 0.72 8.1 20.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF5401 PF17380.2 EEQ39349.1 - 0.94 7.5 29.8 1.1 7.2 29.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) NPR3 PF03666.13 EEQ39349.1 - 1.9 7.2 16.1 2.6 6.7 16.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 U79_P34 PF03064.16 EEQ39349.1 - 1.9 7.8 18.5 3 7.1 18.5 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Presenilin PF01080.17 EEQ39349.1 - 2.2 6.9 13.9 2.7 6.7 13.9 1.1 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 EEQ39349.1 - 2.4 7.9 16.9 3.6 7.3 16.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 EEQ39349.1 - 2.5 7.8 15.8 3.4 7.4 15.8 1.3 1 0 0 1 1 1 0 AAA domain Hid1 PF12722.7 EEQ39349.1 - 2.7 6.0 11.0 2.8 5.9 11.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Exonuc_VII_L PF02601.15 EEQ39349.1 - 3.4 7.2 10.3 4.5 6.7 10.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Zip PF02535.22 EEQ39349.1 - 5.5 6.1 4.9 6.4 5.9 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Tox-ODYAM1 PF15642.6 EEQ39349.1 - 7.4 5.4 10.6 9.1 5.1 10.6 1.1 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus V_ATPase_I PF01496.19 EEQ39349.1 - 8.6 4.1 8.1 11 3.8 8.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XRN_M PF17846.1 EEQ39349.1 - 9.1 5.1 13.2 13 4.6 13.2 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Rad21_Rec8_N PF04825.13 EEQ39350.1 - 4.3e-26 91.2 0.7 8.3e-26 90.3 0.1 1.7 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EEQ39350.1 - 1.5e-07 30.6 0.1 3.5e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein WD40 PF00400.32 EEQ39351.1 - 3.2e-10 40.4 7.1 0.031 15.1 1.4 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39351.1 - 0.035 14.4 0.1 0.32 11.3 0.0 2.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SLD5_C PF16922.5 EEQ39352.1 - 8.7e-11 41.8 0.3 1.5e-10 41.1 0.3 1.4 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EEQ39352.1 - 3.5e-07 30.7 0.2 8.4e-07 29.4 0.2 1.8 1 1 0 1 1 1 1 GINS complex protein WD40 PF00400.32 EEQ39353.1 - 1.6e-10 41.4 4.2 0.00012 22.8 0.2 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EEQ39353.1 - 4.1e-07 29.5 5.5 4.1e-07 29.5 5.5 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EEQ39353.1 - 0.018 15.3 4.7 0.051 13.9 4.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EEQ39353.1 - 0.019 15.3 8.7 0.091 13.1 8.7 2.2 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EEQ39353.1 - 0.021 14.7 1.4 0.086 12.7 1.4 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) BBS2_Mid PF14783.6 EEQ39353.1 - 0.087 12.9 0.0 0.37 10.8 0.0 2.1 1 1 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region C1_1 PF00130.22 EEQ39353.1 - 6.5 6.7 8.4 14 5.6 0.5 2.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Hydrolase_4 PF12146.8 EEQ39354.1 - 3.1e-19 69.2 0.3 6.2e-11 42.0 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ39354.1 - 2e-13 50.6 0.4 8.2e-09 35.5 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ39354.1 - 3.6e-07 31.0 0.9 2.6e-06 28.2 0.4 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EEQ39354.1 - 5.5e-07 29.3 0.3 5.1e-06 26.1 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EEQ39354.1 - 0.00012 21.8 0.0 0.0018 17.9 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 EEQ39354.1 - 0.00034 20.6 0.0 0.082 12.8 0.0 2.9 1 1 2 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 EEQ39354.1 - 0.0016 18.3 0.3 0.0069 16.3 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) UPF0227 PF05728.12 EEQ39354.1 - 0.004 17.1 0.1 0.081 12.9 0.0 2.6 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Esterase PF00756.20 EEQ39354.1 - 0.012 15.2 0.2 0.045 13.4 0.0 1.9 2 0 0 2 2 2 0 Putative esterase DUF818 PF05677.12 EEQ39354.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.16 EEQ39354.1 - 0.018 14.8 0.0 0.7 9.7 0.0 2.1 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 EEQ39354.1 - 0.038 12.6 0.1 0.69 8.5 0.1 2.5 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 EEQ39354.1 - 0.04 13.5 0.0 0.35 10.4 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EEQ39354.1 - 0.056 13.3 0.2 0.2 11.5 0.0 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S28 PF05577.12 EEQ39354.1 - 0.057 12.2 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 IF4E PF01652.18 EEQ39355.1 - 1.4e-54 184.2 2.2 1.7e-54 183.9 2.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E KRE1 PF17056.5 EEQ39356.1 - 9e-26 89.4 13.3 2.1e-25 88.2 13.3 1.6 1 1 0 1 1 1 1 Killer toxin-resistance protein 1 Tir_receptor_N PF07490.11 EEQ39356.1 - 7.2 6.4 10.6 2 8.2 5.8 1.9 1 1 1 2 2 2 0 Translocated intimin receptor (Tir) N-terminus Aa_trans PF01490.18 EEQ39357.1 - 2.9e-30 105.3 14.2 3.6e-30 105.0 14.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF4191 PF13829.6 EEQ39357.1 - 6.9 5.9 6.9 16 4.8 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4191) Aa_trans PF01490.18 EEQ39358.1 - 3e-35 121.7 11.8 3.3e-35 121.6 11.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ApoO PF09769.9 EEQ39359.1 - 6.3e-26 90.9 0.0 1.5e-24 86.4 0.0 2.0 2 0 0 2 2 2 2 Apolipoprotein O ApbA_C PF08546.11 EEQ39360.1 - 1e-05 25.7 0.0 4.6e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DUF3552 PF12072.8 EEQ39360.1 - 0.014 14.8 23.4 0.22 10.9 13.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) EzrA PF06160.12 EEQ39360.1 - 0.025 12.7 11.2 0.045 11.9 11.2 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Jnk-SapK_ap_N PF09744.9 EEQ39360.1 - 0.11 12.7 23.3 0.032 14.5 14.4 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 NAD_binding_2 PF03446.15 EEQ39360.1 - 0.2 11.8 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FapA PF03961.13 EEQ39360.1 - 1.1 7.8 10.4 1.9 7.0 10.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A HMMR_N PF15905.5 EEQ39360.1 - 2 7.8 22.1 0.026 14.0 14.4 1.7 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal V_ATPase_I PF01496.19 EEQ39360.1 - 2.3 6.0 8.0 4.2 5.2 8.0 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM76 PF16046.5 EEQ39360.1 - 4.8 6.5 12.7 2.4 7.5 9.1 2.0 2 0 0 2 2 2 0 FAM76 protein DUF4200 PF13863.6 EEQ39360.1 - 6.6 7.2 38.9 0.073 13.5 20.4 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EEQ39360.1 - 6.9 6.7 6.6 17 5.5 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Thymidylate_kin PF02223.17 EEQ39361.1 - 3.2e-41 141.1 0.0 3.8e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 EEQ39361.1 - 0.0011 19.6 0.0 0.003 18.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain dNK PF01712.19 EEQ39361.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 Deoxynucleoside kinase KTI12 PF08433.10 EEQ39361.1 - 0.0072 15.8 0.1 0.03 13.8 0.0 1.9 2 0 0 2 2 2 1 Chromatin associated protein KTI12 CPT PF07931.12 EEQ39361.1 - 0.0087 15.9 0.0 0.035 14.0 0.0 2.0 2 1 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein CobU PF02283.16 EEQ39361.1 - 0.031 13.9 0.0 0.09 12.3 0.0 1.7 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_33 PF13671.6 EEQ39361.1 - 0.043 14.0 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Clat_adaptor_s PF01217.20 EEQ39362.1 - 5.6e-52 175.5 4.8 7e-52 175.1 4.8 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ku PF02735.16 EEQ39363.1 - 3.3e-26 92.3 0.0 5.6e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 EEQ39363.1 - 3.2e-15 56.6 0.2 1e-14 55.0 0.2 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm Ku_N PF03731.15 EEQ39363.1 - 9.4e-15 54.9 0.2 2e-14 53.9 0.2 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain CENP-B_dimeris PF09026.10 EEQ39363.1 - 0.051 14.0 6.6 0.11 12.9 6.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RXT2_N PF08595.11 EEQ39363.1 - 0.18 11.8 2.5 0.46 10.5 2.5 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EEQ39363.1 - 9.2 5.5 9.8 15 4.8 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein Zn_clus PF00172.18 EEQ39366.1 - 2.1e-08 34.1 15.8 2.1e-08 34.1 15.8 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain His_Phos_1 PF00300.22 EEQ39367.1 - 2.5e-06 27.3 0.1 9.4e-06 25.4 0.1 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CsgA PF17334.2 EEQ39367.1 - 0.018 15.7 0.2 0.055 14.2 0.2 1.8 1 0 0 1 1 1 0 Minor curli fiber component A HEAT PF02985.22 EEQ39368.1 - 4.2e-36 119.9 14.9 0.0028 17.8 0.0 12.4 12 0 0 12 12 12 9 HEAT repeat HEAT_2 PF13646.6 EEQ39368.1 - 2.2e-30 104.9 0.5 8.7e-09 35.7 0.0 7.3 5 3 2 7 7 7 5 HEAT repeats Cnd1 PF12717.7 EEQ39368.1 - 3.7e-12 46.6 14.6 1.5e-06 28.4 0.1 6.3 3 2 2 6 6 6 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEQ39368.1 - 2.1e-08 34.7 3.8 0.0078 16.8 0.0 6.4 4 4 3 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EEQ39368.1 - 5.4e-07 30.0 7.2 2.4 8.8 0.0 7.5 7 1 1 8 8 8 3 HEAT-like repeat API5 PF05918.11 EEQ39368.1 - 0.064 12.1 7.0 4.4 6.0 0.1 4.7 3 2 1 6 6 6 0 Apoptosis inhibitory protein 5 (API5) Fe-S_biosyn PF01521.20 EEQ39369.1 - 3.1e-13 49.9 0.6 4.3e-13 49.4 0.6 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PMT PF02366.18 EEQ39370.1 - 7.6e-92 307.3 17.4 7.6e-92 307.3 17.4 2.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EEQ39370.1 - 4.4e-59 199.4 14.3 4.4e-59 199.4 14.3 2.5 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EEQ39370.1 - 1.8e-25 89.9 0.1 3e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 MIR domain Gp_dh_C PF02800.20 EEQ39371.1 - 4.8e-68 227.7 0.0 6.7e-68 227.2 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EEQ39371.1 - 5.5e-40 135.8 0.0 1e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EEQ39371.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 EEQ39371.1 - 0.023 14.8 0.2 0.14 12.3 0.0 2.4 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Flavin_Reduct PF01613.18 EEQ39371.1 - 0.1 12.6 0.3 0.19 11.8 0.3 1.3 1 1 0 1 1 1 0 Flavin reductase like domain SPX PF03105.19 EEQ39373.1 - 9.6e-06 25.8 0.1 9.6e-06 25.8 0.1 3.5 2 2 0 3 3 3 2 SPX domain Baculo_PEP_C PF04513.12 EEQ39373.1 - 0.22 11.5 3.1 0.7 9.9 2.7 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NIR_SIR PF01077.22 EEQ39374.1 - 3.9e-53 179.2 0.0 1.3e-50 171.0 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EEQ39374.1 - 1.2e-28 98.8 0.0 1.3e-13 50.6 0.0 3.1 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EEQ39374.1 - 1.6e-27 96.5 0.0 3.6e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin DUF5474 PF17568.2 EEQ39375.1 - 0.13 12.3 0.4 0.26 11.4 0.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5474) VWA_2 PF13519.6 EEQ39377.1 - 2.6e-21 76.3 0.2 2.1e-20 73.4 0.0 2.1 1 1 1 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EEQ39377.1 - 1.6e-06 28.5 0.3 2.3e-06 28.0 0.3 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 EEQ39377.1 - 0.00055 19.8 0.0 0.00075 19.4 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like DUF4362 PF14275.6 EEQ39377.1 - 0.00091 19.5 0.3 1.8 8.9 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4362) UIM PF02809.20 EEQ39377.1 - 0.0057 16.5 0.3 0.015 15.1 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Prp18 PF02840.15 EEQ39377.1 - 0.11 12.5 0.3 0.19 11.8 0.3 1.3 1 0 0 1 1 1 0 Prp18 domain GAF PF01590.26 EEQ39378.1 - 0.0032 18.1 0.0 0.0072 17.0 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EEQ39378.1 - 0.0088 16.3 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain Swi3 PF07962.12 EEQ39379.1 - 8e-20 70.6 0.3 1.3e-19 70.0 0.3 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NOA36 PF06524.12 EEQ39379.1 - 5.9 6.1 11.3 4.1 6.7 1.4 2.2 2 0 0 2 2 2 0 NOA36 protein TB2_DP1_HVA22 PF03134.19 EEQ39380.1 - 0.0029 17.5 3.7 0.0029 17.5 3.7 1.8 1 1 1 2 2 2 1 TB2/DP1, HVA22 family Cytochrom_B561 PF03188.16 EEQ39380.1 - 0.59 10.3 4.2 0.65 10.1 2.4 1.9 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 HECT_2 PF09814.9 EEQ39381.1 - 3.6e-55 187.3 2.7 8.8e-55 186.1 2.7 1.5 1 1 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RIG-I_C-RD PF11648.8 EEQ39381.1 - 2.7 8.2 6.9 67 3.8 6.9 2.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I Yippee-Mis18 PF03226.14 EEQ39381.1 - 4.1 7.7 6.3 13 6.1 5.0 2.5 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DHHA2 PF02833.14 EEQ39382.1 - 2e-27 96.2 0.4 5.7e-27 94.7 0.1 1.8 2 0 0 2 2 2 1 DHHA2 domain DHH PF01368.20 EEQ39382.1 - 1.3e-09 38.2 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 DHH family PMT_4TMC PF16192.5 EEQ39383.1 - 1.4e-50 171.7 8.8 1.4e-50 171.7 8.8 3.0 2 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 EEQ39383.1 - 7.2e-40 137.1 21.2 7.2e-40 137.1 21.2 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 EEQ39383.1 - 5.1e-20 72.1 0.8 4.9e-18 65.6 0.2 2.1 1 1 1 2 2 2 2 MIR domain Glyco_transf_25 PF01755.17 EEQ39383.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 1 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Hamartin PF04388.12 EEQ39384.1 - 8.4e-06 24.8 20.2 8.4e-06 24.8 20.2 3.3 1 1 0 2 2 2 1 Hamartin protein DUF2089 PF09862.9 EEQ39384.1 - 0.00093 19.2 0.5 0.17 11.9 0.4 3.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2089) CLZ PF16526.5 EEQ39384.1 - 0.21 12.0 10.0 4.2 7.8 0.1 3.8 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Cob_adeno_trans PF01923.18 EEQ39384.1 - 0.3 11.2 3.0 0.76 9.9 0.8 2.7 2 1 1 3 3 3 0 Cobalamin adenosyltransferase Baculo_PEP_C PF04513.12 EEQ39384.1 - 0.31 11.1 6.0 2.2 8.3 0.2 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 EEQ39384.1 - 0.34 11.0 18.2 1.9 8.5 4.6 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein SlyX PF04102.12 EEQ39384.1 - 2.4 8.8 8.9 44 4.8 1.3 4.3 3 0 0 3 3 3 0 SlyX FliJ PF02050.16 EEQ39384.1 - 2.6 8.3 11.6 1.1 9.5 1.7 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein UPF0242 PF06785.11 EEQ39384.1 - 2.8 8.0 35.6 2.4 8.2 9.3 3.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MscS_porin PF12795.7 EEQ39384.1 - 3.2 7.2 12.1 1.5 8.3 5.6 2.7 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain YscO PF07321.12 EEQ39384.1 - 8.6 6.3 13.2 0.32 10.9 3.6 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO GrpE PF01025.19 EEQ39384.1 - 9.6 5.8 13.7 9.8 5.8 2.7 2.9 1 1 1 2 2 2 0 GrpE MFS_1 PF07690.16 EEQ39386.1 - 5.5e-35 120.9 29.3 5.5e-35 120.9 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily VitK2_biosynth PF02621.14 EEQ39386.1 - 0.087 12.3 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Menaquinone biosynthesis DUF4574 PF15141.6 EEQ39386.1 - 0.15 12.0 0.0 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 CENP-X PF09415.10 EEQ39387.1 - 0.045 14.1 3.3 0.25 11.7 3.3 2.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X PQ-loop PF04193.14 EEQ39388.1 - 5.8e-22 77.2 8.8 7.7e-18 64.0 1.7 2.6 2 0 0 2 2 2 2 PQ loop repeat ABC2_membrane_5 PF13346.6 EEQ39388.1 - 0.0076 15.8 9.6 0.0076 15.8 9.6 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein ER_lumen_recept PF00810.18 EEQ39388.1 - 0.3 11.9 3.1 0.95 10.3 0.1 2.7 2 1 1 3 3 3 0 ER lumen protein retaining receptor Rad4 PF03835.15 EEQ39389.1 - 2.8e-28 98.4 2.8 2.8e-28 98.4 2.8 2.4 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EEQ39389.1 - 1e-18 67.5 0.0 2.2e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EEQ39389.1 - 2e-18 65.9 0.1 4.7e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EEQ39389.1 - 7.3e-11 42.9 12.8 1.1e-10 42.3 0.0 5.3 5 1 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EEQ39389.1 - 3e-05 24.5 0.0 0.00015 22.2 0.0 2.3 2 0 0 2 2 2 1 Transglutaminase-like superfamily Nif11 PF07862.11 EEQ39390.1 - 0.064 13.6 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Nif11 domain Lyase_1 PF00206.20 EEQ39391.1 - 8.5e-117 390.0 0.0 1.1e-116 389.6 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EEQ39391.1 - 1.1e-24 86.6 0.7 2.2e-24 85.6 0.1 1.9 2 0 0 2 2 2 1 Fumarase C C-terminus AATase PF07247.12 EEQ39393.1 - 2.5e-49 168.2 1.7 3.3e-49 167.8 1.7 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase HK PF02110.15 EEQ39394.1 - 5.5e-70 235.6 0.8 8.8e-70 234.9 0.8 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EEQ39394.1 - 1.4e-55 187.5 0.2 2.1e-55 186.9 0.2 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 EEQ39394.1 - 0.025 14.1 0.4 0.025 14.1 0.4 1.9 2 1 0 2 2 2 0 Carbohydrate kinase WLM PF08325.10 EEQ39395.1 - 8.2e-54 182.6 0.7 3e-53 180.8 0.0 2.0 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.17 EEQ39395.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF45 INSIG PF07281.12 EEQ39397.1 - 2.1e-25 89.7 5.1 1.1e-24 87.2 4.9 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF4501 PF14946.6 EEQ39397.1 - 0.051 13.6 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Chordopox_A13L PF05961.11 EEQ39397.1 - 0.22 11.8 0.7 0.8 10.0 0.2 2.2 1 1 1 2 2 2 0 Chordopoxvirus A13L protein Endosulfine PF04667.17 EEQ39399.1 - 5.5e-29 100.1 0.9 7.4e-29 99.7 0.9 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region S-antigen PF05756.11 EEQ39399.1 - 0.0095 16.3 0.7 0.036 14.4 0.1 1.9 2 0 0 2 2 2 1 S-antigen protein Pga1 PF10333.9 EEQ39400.1 - 3.2e-27 95.5 3.1 4.5e-27 95.0 3.1 1.1 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator PTPLA PF04387.14 EEQ39400.1 - 0.27 11.0 2.7 1.4 8.6 0.4 2.5 2 1 0 3 3 3 0 Protein tyrosine phosphatase-like protein, PTPLA F-box PF00646.33 EEQ39401.1 - 1.6e-06 27.8 2.2 5e-06 26.2 2.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EEQ39401.1 - 5.3e-06 26.2 1.9 6.3e-06 26.0 0.5 1.9 2 0 0 2 2 2 1 F-box-like ThiF PF00899.21 EEQ39402.1 - 7.2e-60 202.4 0.0 1.1e-59 201.8 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EEQ39402.1 - 6.7e-13 49.1 0.0 1.6e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 EEQ39402.1 - 0.0056 16.8 0.0 0.024 14.7 0.0 2.1 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase bZIP_2 PF07716.15 EEQ39402.1 - 0.0081 16.2 2.0 0.02 15.0 2.0 1.7 1 0 0 1 1 1 1 Basic region leucine zipper DUF3958 PF13125.6 EEQ39402.1 - 0.047 13.9 1.9 0.082 13.1 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) FadA PF09403.10 EEQ39402.1 - 0.058 13.9 0.2 0.13 12.7 0.2 1.6 1 0 0 1 1 1 0 Adhesion protein FadA UDPG_MGDP_dh_N PF03721.14 EEQ39402.1 - 0.15 11.6 1.1 0.73 9.4 0.8 2.0 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TSC22 PF01166.18 EEQ39402.1 - 0.16 12.3 0.2 0.41 11.0 0.2 1.7 1 0 0 1 1 1 0 TSC-22/dip/bun family Rad60-SLD PF11976.8 EEQ39404.1 - 1.7e-16 59.8 0.9 4.4e-16 58.5 0.9 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF908 PF06012.12 EEQ39404.1 - 0.066 12.6 5.7 0.1 12.0 5.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Got1 PF04178.12 EEQ39405.1 - 4.9e-27 94.6 17.3 6.6e-27 94.2 17.3 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family HIT PF01230.23 EEQ39406.1 - 4.4e-25 88.3 0.2 6.1e-25 87.8 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EEQ39406.1 - 2.9e-14 53.5 0.3 5.2e-14 52.7 0.1 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EEQ39406.1 - 0.0014 18.5 1.7 0.0031 17.4 1.7 1.7 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 EVE PF01878.18 EEQ39406.1 - 0.097 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 EVE domain AAA PF00004.29 EEQ39407.1 - 1.3e-97 323.3 0.0 1.2e-47 161.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ39407.1 - 3.2e-26 90.8 4.5 6.8e-13 48.2 1.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EEQ39407.1 - 4.7e-19 68.4 0.9 2e-18 66.4 0.3 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EEQ39407.1 - 1.9e-14 54.1 0.0 1.6e-07 31.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EEQ39407.1 - 7.1e-14 51.9 0.0 6.5e-06 26.0 0.0 3.1 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EEQ39407.1 - 1.5e-11 45.0 0.0 0.00042 20.8 0.1 4.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.6 EEQ39407.1 - 3.1e-11 43.6 0.0 1.5e-05 25.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.17 EEQ39407.1 - 3.1e-11 42.9 0.0 7.8e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 EEQ39407.1 - 4.1e-11 43.0 0.6 1.6e-05 24.9 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EEQ39407.1 - 6.3e-10 38.8 1.8 0.0012 18.1 0.0 3.3 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_22 PF13401.6 EEQ39407.1 - 1.4e-08 35.1 2.7 0.06 13.6 0.0 4.8 3 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.17 EEQ39407.1 - 2.3e-07 30.7 0.1 0.017 14.8 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 EEQ39407.1 - 2.9e-07 30.6 0.0 0.01 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EEQ39407.1 - 3.2e-07 30.3 1.8 8.9e-06 25.6 0.3 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 EEQ39407.1 - 5.2e-07 30.0 0.0 0.03 14.7 0.0 3.3 4 0 0 4 4 2 2 RNA helicase Mg_chelatase PF01078.21 EEQ39407.1 - 5.4e-07 29.2 0.6 0.032 13.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EEQ39407.1 - 4.3e-06 27.3 0.0 0.19 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EEQ39407.1 - 7.3e-06 25.5 1.1 0.45 9.8 0.1 3.6 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 EEQ39407.1 - 1.7e-05 24.5 0.1 0.13 11.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 EEQ39407.1 - 2.5e-05 24.8 0.2 0.19 12.3 0.0 3.9 3 1 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.26 EEQ39407.1 - 4.4e-05 23.2 0.1 0.27 10.9 0.0 3.4 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 EEQ39407.1 - 5.6e-05 23.5 0.0 0.44 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EEQ39407.1 - 7.6e-05 22.4 6.8 0.56 9.8 1.4 4.3 2 2 1 3 3 3 1 AAA domain Parvo_NS1 PF01057.17 EEQ39407.1 - 0.00011 21.4 0.2 0.42 9.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 EEQ39407.1 - 0.00012 22.0 0.0 0.058 13.2 0.0 2.7 3 0 0 3 3 2 1 Bacterial dnaA protein ResIII PF04851.15 EEQ39407.1 - 0.00017 21.6 0.5 0.038 14.0 0.0 2.9 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EEQ39407.1 - 0.00022 20.7 2.5 0.12 11.9 0.1 2.8 3 0 0 3 3 3 2 PhoH-like protein AAA_11 PF13086.6 EEQ39407.1 - 0.00024 21.0 2.7 1.5 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 EEQ39407.1 - 0.00037 20.4 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EEQ39407.1 - 0.00042 20.3 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EEQ39407.1 - 0.00061 19.6 4.6 0.1 12.3 0.0 3.4 4 1 0 4 4 3 2 AAA domain DUF815 PF05673.13 EEQ39407.1 - 0.00064 19.0 0.0 0.64 9.1 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.6 EEQ39407.1 - 0.00095 19.6 3.5 0.43 11.0 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_19 PF13245.6 EEQ39407.1 - 0.0018 18.6 0.5 4 7.8 0.0 3.7 3 1 0 4 4 3 0 AAA domain AAA_30 PF13604.6 EEQ39407.1 - 0.0022 17.8 0.5 2.5 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EEQ39407.1 - 0.0026 17.7 0.2 5.8 6.8 0.0 3.3 3 0 0 3 3 3 0 NACHT domain DUF2075 PF09848.9 EEQ39407.1 - 0.0033 16.7 0.5 2.4 7.3 0.0 2.7 3 0 0 3 3 2 2 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 EEQ39407.1 - 0.0043 16.3 0.1 1.6 7.9 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin ATPase_2 PF01637.18 EEQ39407.1 - 0.0093 15.9 2.4 1.7 8.5 0.1 4.2 4 1 0 4 4 3 1 ATPase domain predominantly from Archaea IPT PF01745.16 EEQ39407.1 - 0.017 14.5 0.2 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Sigma54_activ_2 PF14532.6 EEQ39407.1 - 0.018 15.1 0.0 3 8.0 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 EEQ39407.1 - 0.023 13.9 0.4 0.83 8.8 0.0 2.8 3 1 1 4 4 3 0 KAP family P-loop domain NTPase_1 PF03266.15 EEQ39407.1 - 0.026 14.5 1.4 8.3 6.3 0.0 4.1 4 0 0 4 4 4 0 NTPase Cytidylate_kin PF02224.18 EEQ39407.1 - 0.03 14.0 0.0 9.8 5.8 0.0 3.0 2 0 0 2 2 2 0 Cytidylate kinase NB-ARC PF00931.22 EEQ39407.1 - 0.041 13.1 0.2 7.7 5.6 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Molydop_binding PF01568.21 EEQ39407.1 - 0.049 13.7 0.1 0.18 11.9 0.1 1.9 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain T2SSE PF00437.20 EEQ39407.1 - 0.055 12.5 0.0 7.7 5.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 EEQ39407.1 - 0.082 12.6 0.0 17 5.1 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase eIF-1a PF01176.19 EEQ39407.1 - 0.12 12.2 0.6 0.51 10.2 0.5 2.2 1 1 0 1 1 1 0 Translation initiation factor 1A / IF-1 AAA_6 PF12774.7 EEQ39407.1 - 0.31 10.0 0.7 9.1 5.1 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region Sigma70_ner PF04546.13 EEQ39407.1 - 0.83 9.5 9.1 0.68 9.8 6.8 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region SRPRB PF09439.10 EEQ39407.1 - 1.6 8.2 5.4 21 4.5 0.0 3.9 4 1 0 4 4 3 0 Signal recognition particle receptor beta subunit ABC2_membrane PF01061.24 EEQ39409.1 - 1.6e-82 276.0 56.8 1.5e-44 151.9 22.7 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EEQ39409.1 - 2.9e-39 134.7 0.1 2.6e-18 66.9 0.0 3.3 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 EEQ39409.1 - 4.8e-36 122.5 4.9 9.4e-35 118.4 0.3 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EEQ39409.1 - 2.2e-17 63.4 0.5 5.4e-17 62.2 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EEQ39409.1 - 1.1e-09 38.4 0.1 1.3e-06 28.4 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase AAA_25 PF13481.6 EEQ39409.1 - 9.2e-07 28.6 1.2 0.0001 22.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 EEQ39409.1 - 2.8e-06 26.7 36.1 0.00025 20.3 17.2 3.1 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 EEQ39409.1 - 5.6e-05 23.6 0.2 0.00045 20.7 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 EEQ39409.1 - 0.00058 20.1 0.8 0.0043 17.3 0.1 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EEQ39409.1 - 0.0015 18.6 0.0 0.53 10.4 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SMC_N PF02463.19 EEQ39409.1 - 0.0022 17.5 0.0 0.084 12.3 0.0 2.7 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EEQ39409.1 - 0.0029 17.9 0.1 0.27 11.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EEQ39409.1 - 0.0038 17.0 0.0 0.03 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ39409.1 - 0.0048 17.4 0.2 0.37 11.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 EEQ39409.1 - 0.0052 16.5 1.7 0.12 12.1 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EEQ39409.1 - 0.0062 16.4 0.0 1.4 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EEQ39409.1 - 0.01 16.3 9.4 0.026 15.1 0.2 3.3 3 1 1 4 4 3 0 AAA domain NACHT PF05729.12 EEQ39409.1 - 0.015 15.3 1.3 0.63 9.9 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_17 PF13207.6 EEQ39409.1 - 0.016 15.6 0.2 1.5 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EEQ39409.1 - 0.018 15.2 0.1 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EEQ39409.1 - 0.024 14.4 0.1 3.5 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 EEQ39409.1 - 0.085 12.7 0.0 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase NTPase_1 PF03266.15 EEQ39409.1 - 0.2 11.5 0.7 3.3 7.6 0.0 2.8 3 0 0 3 3 3 0 NTPase cobW PF02492.19 EEQ39409.1 - 2.1 7.9 3.4 3.1 7.4 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain YCII PF03795.14 EEQ39410.1 - 0.00031 21.1 0.0 0.00041 20.7 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain BPTA PF17044.5 EEQ39411.1 - 0.0037 17.1 0.1 0.0048 16.8 0.1 1.1 1 0 0 1 1 1 1 Borrelial persistence in ticks protein A Profilin PF00235.19 EEQ39412.1 - 1.6e-47 160.9 0.5 1.8e-47 160.8 0.5 1.0 1 0 0 1 1 1 1 Profilin ThiF PF00899.21 EEQ39413.1 - 1.6e-63 214.3 0.0 2e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EEQ39413.1 - 8.6e-09 35.7 5.0 1.7e-05 24.9 0.6 2.4 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 EEQ39413.1 - 0.018 15.1 0.0 0.039 14.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EEQ39413.1 - 0.054 13.7 0.7 0.66 10.2 0.0 2.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Wzt_C PF14524.6 EEQ39414.1 - 0.05 13.6 0.1 0.09 12.8 0.1 1.5 1 0 0 1 1 1 0 Wzt C-terminal domain Glycos_transf_2 PF00535.26 EEQ39415.1 - 1.2e-34 119.6 0.0 1.4e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EEQ39415.1 - 1.2e-10 41.7 0.0 1.6e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EEQ39415.1 - 0.00058 19.4 0.0 0.00079 19.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EEQ39415.1 - 0.0016 18.0 0.0 0.0025 17.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_transf_7N PF13733.6 EEQ39415.1 - 0.031 13.9 0.0 0.053 13.2 0.0 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 zf-RanBP PF00641.18 EEQ39416.1 - 1.3e-16 59.6 14.3 3.3e-10 39.1 1.4 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EEQ39416.1 - 6.8e-08 32.2 0.3 1e-06 28.5 0.0 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSN1_7TM PF02714.15 EEQ39417.1 - 3e-81 272.8 34.5 5.1e-81 272.0 33.0 2.1 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEQ39417.1 - 4e-34 117.6 2.2 4e-34 117.6 2.2 2.9 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EEQ39417.1 - 4.9e-21 75.7 0.0 7.2e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Zn_clus PF00172.18 EEQ39418.1 - 1.6e-09 37.7 5.9 1.6e-09 37.7 5.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PX PF00787.24 EEQ39419.1 - 2.2e-14 53.4 0.0 6.8e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 EEQ39419.1 - 1.5e-10 40.5 0.1 2.7e-09 36.5 0.0 2.7 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.6 EEQ39419.1 - 4.9e-07 29.5 0.1 4e-06 26.6 0.0 2.5 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.17 EEQ39419.1 - 5e-05 22.9 0.0 0.00018 21.1 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain PX PF00787.24 EEQ39420.1 - 1.5e-08 34.6 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 PX domain SH3_1 PF00018.28 EEQ39420.1 - 6e-08 32.2 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ39420.1 - 8.3e-06 25.6 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3665 PF12427.8 EEQ39420.1 - 0.15 11.7 0.3 0.75 9.5 0.0 2.1 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Pkinase PF00069.25 EEQ39421.1 - 6.7e-73 245.3 0.3 8.4e-73 245.0 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39421.1 - 1.6e-40 139.0 0.0 2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ39421.1 - 7.9e-06 24.9 0.0 1.9e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEQ39421.1 - 1.7e-05 24.3 0.0 3.9e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ39421.1 - 0.0012 17.8 0.4 0.0018 17.3 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 EEQ39421.1 - 0.007 17.1 1.0 0.007 17.1 1.0 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Peptidase_C12 PF01088.21 EEQ39423.1 - 1.8e-49 168.3 0.0 2.1e-49 168.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 SAC3_GANP PF03399.16 EEQ39424.1 - 3.3e-17 62.8 7.5 4.3e-15 55.9 7.5 2.5 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EEQ39424.1 - 0.00067 19.6 0.2 0.0019 18.2 0.2 1.7 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family CMS1 PF14617.6 EEQ39424.1 - 0.034 13.5 2.0 0.042 13.2 0.8 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Mfa1 PF17445.2 EEQ39424.1 - 0.12 12.5 0.3 0.39 10.8 0.3 1.9 1 0 0 1 1 1 0 Mating factor A1 Sel1 PF08238.12 EEQ39426.1 - 2e-09 37.8 1.3 0.022 15.5 0.2 3.5 3 0 0 3 3 3 3 Sel1 repeat Peptidase_M1 PF01433.20 EEQ39427.1 - 4.3e-51 173.6 0.8 6.7e-51 172.9 0.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EEQ39427.1 - 7.7e-36 122.6 0.1 2.6e-35 120.9 0.0 2.0 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EEQ39427.1 - 3e-23 83.0 0.0 4.9e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 EEQ39427.1 - 0.045 13.5 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M48 Ribosomal_S8 PF00410.19 EEQ39428.1 - 5.1e-24 84.6 0.1 7.7e-24 84.1 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 DUF3445 PF11927.8 EEQ39430.1 - 3.1e-65 220.0 0.5 4e-65 219.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) MFS_1 PF07690.16 EEQ39431.1 - 6.3e-31 107.6 54.1 2e-22 79.6 33.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2012 PF09430.10 EEQ39432.1 - 1.8e-08 34.5 0.2 2.7e-08 34.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF4199 PF13858.6 EEQ39432.1 - 0.034 14.6 0.8 0.034 14.6 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) TPT PF03151.16 EEQ39433.1 - 8.8e-25 87.6 16.3 1.5e-14 54.1 7.3 2.4 3 0 0 3 3 3 2 Triose-phosphate Transporter family Beach PF02138.18 EEQ39434.1 - 7.3e-123 409.3 0.6 2.5e-122 407.6 0.0 2.1 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 EEQ39434.1 - 3.1e-08 33.6 0.2 1.3e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EEQ39434.1 - 0.0012 19.6 2.0 2.1 9.3 0.0 3.5 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF4704 PF15787.5 EEQ39434.1 - 0.0089 15.3 0.0 0.04 13.2 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) UCH PF00443.29 EEQ39435.1 - 6.7e-73 245.3 1.1 1.5e-72 244.2 1.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ39435.1 - 1.9e-11 44.1 0.3 0.00015 21.5 0.1 3.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EEQ39435.1 - 1.3e-06 28.3 0.8 0.0015 18.3 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-specific protease C-terminal PI3K_C2 PF00792.24 EEQ39435.1 - 0.012 15.5 0.1 0.051 13.5 0.1 2.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 DUF4482 PF14818.6 EEQ39435.1 - 5 8.0 10.9 0.41 11.5 3.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) RNase_PH PF01138.21 EEQ39436.1 - 1.7e-16 61.0 0.0 1.3e-15 58.1 0.0 2.1 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEQ39436.1 - 0.0023 17.9 0.2 0.0045 17.0 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 StbA PF06406.11 EEQ39436.1 - 0.077 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 StbA protein GATase_2 PF00310.21 EEQ39437.1 - 2.2e-176 586.7 0.0 3.1e-176 586.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EEQ39437.1 - 9.4e-151 502.1 0.1 2e-150 501.0 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EEQ39437.1 - 2.6e-114 381.4 0.2 5.2e-113 377.2 0.2 2.2 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 EEQ39437.1 - 7.7e-83 276.8 4.5 1.3e-82 276.1 4.5 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 EEQ39437.1 - 1.3e-21 76.5 0.4 1.3e-21 76.5 0.4 1.9 2 0 0 2 2 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 EEQ39437.1 - 6.5e-21 74.8 1.1 1.1e-19 70.8 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ39437.1 - 3.7e-10 40.2 0.0 1.5e-06 28.6 0.0 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ39437.1 - 9.3e-09 35.4 0.0 3.2e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EEQ39437.1 - 3.6e-07 29.8 0.0 6.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 EEQ39437.1 - 1.6e-05 24.3 0.6 0.016 14.5 0.1 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EEQ39437.1 - 4.4e-05 23.0 0.1 9.2e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EEQ39437.1 - 0.00015 20.6 1.1 0.00025 19.9 0.0 1.9 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.24 EEQ39437.1 - 0.00018 21.3 0.3 0.0012 18.5 0.1 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EEQ39437.1 - 0.00038 19.8 0.1 0.0028 17.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EEQ39437.1 - 0.0007 18.9 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 EEQ39437.1 - 0.0018 17.5 0.0 0.0039 16.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EEQ39437.1 - 0.0044 16.4 0.1 0.041 13.3 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EEQ39437.1 - 0.0047 17.0 0.2 0.32 11.1 0.0 2.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EEQ39437.1 - 0.0048 16.9 0.2 0.022 14.8 0.0 2.1 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_7 PF13241.6 EEQ39437.1 - 0.02 15.3 0.6 2.3 8.7 0.0 3.1 3 0 0 3 3 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EEQ39437.1 - 0.054 12.8 0.1 3.1 7.0 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FMN_dh PF01070.18 EEQ39437.1 - 0.085 11.9 0.0 0.32 10.0 0.0 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase NAD_binding_9 PF13454.6 EEQ39437.1 - 0.097 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding ArenaCapSnatch PF17296.2 EEQ39437.1 - 0.11 11.9 0.0 0.63 9.5 0.0 2.2 2 0 0 2 2 2 0 Arenavirus cap snatching domain CarS-like PF01864.17 EEQ39437.1 - 0.17 11.8 0.4 0.56 10.2 0.3 1.8 2 0 0 2 2 2 0 CDP-archaeol synthase IlvN PF07991.12 EEQ39437.1 - 0.37 10.4 2.3 0.84 9.2 0.0 2.5 3 0 0 3 3 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GIDA PF01134.22 EEQ39437.1 - 0.51 9.4 3.9 0.31 10.1 0.0 2.5 3 0 0 3 3 2 0 Glucose inhibited division protein A Recep_L_domain PF01030.24 EEQ39438.1 - 7.1e-06 26.1 3.2 0.014 15.5 1.8 4.0 1 1 3 4 4 4 3 Receptor L domain LRR_4 PF12799.7 EEQ39438.1 - 0.29 11.6 10.6 14 6.3 0.4 4.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Apt1 PF10351.9 EEQ39438.1 - 7.1 5.4 9.7 11 4.8 9.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BORCS6 PF10157.9 EEQ39438.1 - 7.1 6.8 10.3 0.4 10.9 0.3 2.4 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Fasciclin PF02469.22 EEQ39439.1 - 3.2e-05 24.2 0.0 6.8e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Fasciclin domain GAT PF03127.14 EEQ39440.1 - 1.3e-17 63.9 0.2 1.3e-17 63.9 0.2 2.4 2 1 0 2 2 2 1 GAT domain Alpha_adaptinC2 PF02883.20 EEQ39440.1 - 9.2e-16 58.1 0.0 9.2e-16 58.1 0.0 2.7 2 1 1 3 3 3 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 EEQ39440.1 - 2.8e-07 30.0 0.1 1e-06 28.2 0.1 1.9 1 0 0 1 1 1 1 GGA N-GAT domain VHS PF00790.19 EEQ39440.1 - 0.00019 21.3 0.5 0.00047 20.0 0.1 2.0 2 0 0 2 2 2 1 VHS domain Hrs_helical PF12210.8 EEQ39440.1 - 0.016 15.7 0.1 0.072 13.6 0.1 2.0 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Seryl_tRNA_N PF02403.22 EEQ39440.1 - 1.1 9.5 9.6 8 6.8 0.8 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2524 PF10732.9 EEQ39441.1 - 0.017 15.4 3.5 0.067 13.5 2.8 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2524) AP1AR PF15745.5 EEQ39441.1 - 0.035 13.7 0.9 0.044 13.4 0.9 1.1 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein Snapin_Pallidin PF14712.6 EEQ39441.1 - 0.048 14.1 1.5 0.092 13.2 1.1 1.7 1 1 0 1 1 1 0 Snapin/Pallidin MSA-2c PF12238.8 EEQ39441.1 - 0.23 11.4 3.0 0.25 11.3 3.0 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Coq4 PF05019.13 EEQ39443.1 - 9.5e-94 312.8 0.0 1.4e-93 312.3 0.0 1.3 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 RIIa PF02197.17 EEQ39443.1 - 0.095 12.4 0.3 0.7 9.6 0.1 2.4 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit FHA PF00498.26 EEQ39444.1 - 2.2e-14 53.5 0.0 6.1e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EEQ39444.1 - 0.0034 17.7 0.0 0.008 16.5 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF4407 PF14362.6 EEQ39444.1 - 0.2 11.0 4.7 0.32 10.3 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 EEQ39444.1 - 1.4 7.6 9.8 2.8 6.7 9.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Fib_alpha PF08702.10 EEQ39444.1 - 3.3 7.9 10.4 7.3 6.8 3.7 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 EEQ39444.1 - 6.8 6.8 15.8 2.4 8.2 10.9 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BPL_LplA_LipB PF03099.19 EEQ39445.1 - 8.7e-12 45.1 0.1 1.3e-11 44.6 0.1 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family MiAMP1 PF09117.10 EEQ39445.1 - 0.11 12.7 0.0 1.1 9.6 0.1 2.1 2 0 0 2 2 2 0 MiAMP1 PXA PF02194.15 EEQ39446.1 - 1.8e-31 109.5 1.5 3.4e-31 108.6 1.5 1.5 1 0 0 1 1 1 1 PXA domain DUF1322 PF07032.11 EEQ39447.1 - 0.11 13.0 0.1 0.38 11.3 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1322) CybS PF05328.12 EEQ39449.1 - 2.8e-52 175.9 0.1 3.3e-52 175.7 0.1 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit TPR_19 PF14559.6 EEQ39450.1 - 0.049 14.1 0.0 0.18 12.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat VirK PF06903.12 EEQ39450.1 - 0.099 12.7 0.0 0.98 9.5 0.0 2.1 2 0 0 2 2 2 0 VirK protein DHHC PF01529.20 EEQ39451.1 - 3.8e-34 117.7 14.1 3.8e-34 117.7 14.1 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Nipped-B_C PF12830.7 EEQ39452.1 - 1.7e-35 122.7 11.3 1.7e-35 122.7 4.8 2.9 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EEQ39452.1 - 2.9e-10 40.2 2.1 3.1e-09 37.0 0.2 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion DUF4168 PF13767.6 EEQ39452.1 - 0.08 14.1 0.0 0.52 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) RICTOR_M PF14666.6 EEQ39452.1 - 0.86 9.4 7.0 0.21 11.4 0.1 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain SAS4 PF15460.6 EEQ39453.1 - 1.4e-30 105.3 8.8 1.4e-30 105.3 8.8 1.8 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 Cwf_Cwc_15 PF04889.12 EEQ39453.1 - 0.38 10.5 28.2 0.75 9.5 28.2 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SID-1_RNA_chan PF13965.6 EEQ39453.1 - 0.86 7.9 1.7 0.98 7.8 1.7 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NOA36 PF06524.12 EEQ39453.1 - 0.93 8.8 17.4 0.56 9.5 15.6 1.5 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 EEQ39453.1 - 2.5 6.1 15.8 3.6 5.6 15.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi TFIIA PF03153.13 EEQ39453.1 - 3.6 7.5 11.8 4.4 7.2 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CENP-B_dimeris PF09026.10 EEQ39453.1 - 8.4 6.9 19.1 16 6.0 19.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Metallophos PF00149.28 EEQ39454.1 - 1.2e-14 55.3 1.0 1.9e-14 54.6 1.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec10 PF07393.11 EEQ39455.1 - 5.7e-176 587.0 16.8 6.8e-176 586.7 16.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Efg1 PF10153.9 EEQ39455.1 - 0.0071 16.7 1.5 0.0071 16.7 1.5 2.1 2 0 0 2 2 2 1 rRNA-processing protein Efg1 THP2 PF09432.10 EEQ39455.1 - 0.25 11.4 5.4 0.28 11.2 0.3 3.2 3 0 0 3 3 3 0 Tho complex subunit THP2 DUF1664 PF07889.12 EEQ39455.1 - 6.2 6.9 7.6 7.2 6.7 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ubiquitin PF00240.23 EEQ39456.1 - 5.7e-34 115.7 0.6 1.2e-33 114.7 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EEQ39456.1 - 7.6e-27 93.2 2.4 2e-26 91.9 2.4 1.8 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EEQ39456.1 - 3.5e-16 58.8 0.7 7.3e-16 57.8 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEQ39456.1 - 3.7e-05 24.1 0.5 0.00016 22.1 0.2 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEQ39456.1 - 0.0017 18.4 0.4 0.0034 17.5 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EEQ39456.1 - 0.0044 17.3 0.4 0.009 16.3 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain DZR PF12773.7 EEQ39456.1 - 0.0058 16.6 1.2 0.014 15.4 1.2 1.7 1 1 0 1 1 1 1 Double zinc ribbon TBK1_ULD PF18396.1 EEQ39456.1 - 0.0071 16.3 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EEQ39456.1 - 0.014 15.9 0.4 0.02 15.4 0.4 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EEQ39456.1 - 0.035 14.2 1.0 7.8 6.6 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 EEQ39456.1 - 0.036 14.3 0.4 0.076 13.3 0.4 1.5 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Plexin_cytopl PF08337.12 EEQ39456.1 - 0.1 11.2 0.7 2.8 6.5 0.2 2.0 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain zinc_ribbon_5 PF13719.6 EEQ39456.1 - 0.28 11.0 3.3 2.3 8.1 0.2 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EEQ39456.1 - 0.82 9.5 6.8 2.3 8.1 0.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Phosducin PF02114.16 EEQ39457.1 - 2.8e-09 36.3 0.1 3.7e-09 35.9 0.1 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EEQ39457.1 - 3.1e-07 30.3 0.0 5.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin S100PBPR PF15427.6 EEQ39457.1 - 0.0081 15.5 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 S100P-binding protein DUF3196 PF11428.8 EEQ39457.1 - 0.03 13.8 0.5 0.052 13.1 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3196) DUF5321 PF17254.2 EEQ39457.1 - 0.036 13.5 3.1 0.03 13.8 1.7 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5321) FliT PF05400.13 EEQ39457.1 - 0.037 14.8 1.6 0.061 14.1 1.6 1.3 1 0 0 1 1 1 0 Flagellar protein FliT B-block_TFIIIC PF04182.12 EEQ39457.1 - 0.071 13.3 0.1 17 5.7 0.0 2.4 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC Redoxin PF08534.10 EEQ39457.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Redoxin HEXIM PF15313.6 EEQ39457.1 - 6.6 6.9 8.6 1.3 9.2 5.2 1.5 2 0 0 2 2 2 0 Hexamethylene bis-acetamide-inducible protein Tir_receptor_C PF07489.11 EEQ39458.1 - 0.021 14.8 0.1 0.03 14.3 0.1 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus PRELI PF04707.14 EEQ39459.1 - 4.4e-50 169.6 0.8 4.4e-50 169.6 0.8 1.4 2 0 0 2 2 2 1 PRELI-like family CBFD_NFYB_HMF PF00808.23 EEQ39459.1 - 0.13 12.5 0.7 0.27 11.5 0.1 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M16 PF00675.20 EEQ39460.1 - 5.8e-50 169.2 0.1 3.7e-49 166.5 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEQ39460.1 - 1.4e-31 110.0 0.0 3.8e-31 108.5 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Syntaxin-6_N PF09177.11 EEQ39460.1 - 0.031 14.8 2.9 1.1 9.9 0.4 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Ada3 PF10198.9 EEQ39461.1 - 3e-40 137.4 6.1 3e-40 137.4 6.1 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 Mu-like_Pro PF10123.9 EEQ39461.1 - 0.011 15.3 2.0 0.025 14.1 0.4 2.1 2 0 0 2 2 2 0 Mu-like prophage I protein FAM104 PF15434.6 EEQ39461.1 - 0.13 12.9 4.6 0.062 13.9 1.5 2.2 2 0 0 2 2 2 0 Family 104 SlyX PF04102.12 EEQ39461.1 - 0.16 12.6 2.9 8.5 7.1 0.2 3.3 2 0 0 2 2 2 0 SlyX KIAA1430 PF13879.6 EEQ39461.1 - 0.81 10.5 7.8 0.16 12.8 1.8 2.6 2 0 0 2 2 2 0 KIAA1430 homologue CCDC53 PF10152.9 EEQ39461.1 - 6 7.3 11.1 0.36 11.3 2.2 2.9 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex RP-C_C PF11800.8 EEQ39461.1 - 6 6.9 9.4 8.9 6.4 1.0 3.1 3 0 0 3 3 3 0 Replication protein C C-terminal region MRP-S28 PF10213.9 EEQ39462.1 - 5.9e-37 126.9 4.9 1.1e-36 126.1 4.9 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein SRAP PF02586.14 EEQ39463.1 - 7.5e-38 130.3 0.2 1.3e-37 129.5 0.2 1.4 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) PAF PF15715.5 EEQ39463.1 - 0.31 11.6 12.2 0.046 14.3 8.0 1.9 2 0 0 2 2 2 0 PCNA-associated factor histone like domain Aldo_ket_red PF00248.21 EEQ39464.1 - 1.9e-44 152.1 0.0 2.3e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family CobT_C PF11775.8 EEQ39464.1 - 0.091 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT VWA domain zf-H2C2_5 PF13909.6 EEQ39465.1 - 0.069 12.9 1.2 0.31 10.8 0.5 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PSI_PsaE PF02427.17 EEQ39465.1 - 0.079 12.7 0.1 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE AAA PF00004.29 EEQ39467.1 - 1.1e-53 181.1 0.3 2.3e-38 131.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ39467.1 - 2.1e-10 40.3 0.1 6.3e-10 38.7 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EEQ39467.1 - 5.6e-10 39.6 0.5 0.00034 20.9 0.1 3.8 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EEQ39467.1 - 1e-08 35.7 0.1 0.00049 20.5 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 EEQ39467.1 - 2.1e-08 34.1 0.1 0.0014 18.4 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EEQ39467.1 - 1.2e-07 31.8 0.3 0.0019 18.2 0.1 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ39467.1 - 2.1e-07 31.3 0.1 1.8e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) CDC48_N PF02359.18 EEQ39467.1 - 2.3e-07 30.9 0.0 7.3e-07 29.3 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.13 EEQ39467.1 - 4.8e-06 26.0 1.2 0.029 13.6 0.0 2.5 3 0 0 3 3 2 2 TIP49 P-loop domain AAA_18 PF13238.6 EEQ39467.1 - 6.3e-06 26.8 0.1 0.016 15.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EEQ39467.1 - 1e-05 25.3 0.0 0.099 12.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EEQ39467.1 - 1.1e-05 24.9 0.3 0.0078 15.6 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EEQ39467.1 - 1.2e-05 25.1 0.0 0.024 14.4 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 EEQ39467.1 - 6.1e-05 23.4 0.0 0.33 11.4 0.0 3.1 3 0 0 3 3 2 2 RNA helicase AAA_3 PF07726.11 EEQ39467.1 - 6.4e-05 22.8 0.0 0.084 12.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EEQ39467.1 - 7e-05 22.4 0.0 0.08 12.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 EEQ39467.1 - 7.2e-05 22.6 0.0 0.089 12.5 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein TsaE PF02367.17 EEQ39467.1 - 0.00025 21.1 0.0 0.27 11.2 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EEQ39467.1 - 0.00036 20.0 0.3 0.091 12.1 0.1 3.2 3 0 0 3 3 3 1 KaiC AAA_33 PF13671.6 EEQ39467.1 - 0.00041 20.5 0.0 0.2 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EEQ39467.1 - 0.00041 19.8 0.1 1.7 8.0 0.0 3.8 4 0 0 4 4 4 1 Bacterial TniB protein ABC_tran PF00005.27 EEQ39467.1 - 0.00049 20.6 0.8 0.046 14.2 0.1 2.8 3 0 0 3 3 2 1 ABC transporter AAA_25 PF13481.6 EEQ39467.1 - 0.00056 19.5 0.1 1.8 8.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain NB-ARC PF00931.22 EEQ39467.1 - 0.00091 18.5 0.1 0.37 9.9 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain CDC48_2 PF02933.17 EEQ39467.1 - 0.0035 17.1 0.1 0.11 12.3 0.0 2.7 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 PhoH PF02562.16 EEQ39467.1 - 0.0054 16.2 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 EEQ39467.1 - 0.0054 16.8 0.1 0.39 10.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EEQ39467.1 - 0.0055 16.0 0.3 0.71 9.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 EEQ39467.1 - 0.0075 16.2 0.5 1.4 8.8 0.0 2.9 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.11 EEQ39467.1 - 0.014 15.5 0.0 0.91 9.6 0.0 2.7 2 0 0 2 2 2 0 Torsin Sigma54_activ_2 PF14532.6 EEQ39467.1 - 0.016 15.3 0.0 3.5 7.7 0.0 2.8 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EEQ39467.1 - 0.017 15.5 0.0 1 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EEQ39467.1 - 0.023 14.0 0.3 0.56 9.5 0.0 2.6 3 0 0 3 3 2 0 Zeta toxin AAA_11 PF13086.6 EEQ39467.1 - 0.026 14.3 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EEQ39467.1 - 0.031 14.2 0.7 0.64 9.9 0.1 3.1 3 1 0 3 3 2 0 Rad17 P-loop domain AAA_17 PF13207.6 EEQ39467.1 - 0.049 14.1 0.1 14 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EEQ39467.1 - 0.062 13.5 0.0 3.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 EEQ39467.1 - 0.072 13.2 0.1 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Parvo_NS1 PF01057.17 EEQ39467.1 - 0.081 12.0 0.0 2.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EEQ39467.1 - 0.091 12.5 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Vps4_C PF09336.10 EEQ39467.1 - 0.14 12.1 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AhpC-TSA PF00578.21 EEQ39468.1 - 1.7e-32 112.0 0.0 2.3e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEQ39468.1 - 1.8e-16 60.2 0.0 2.4e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EEQ39468.1 - 3.5e-12 45.9 0.0 7.4e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EEQ39468.1 - 0.0012 18.7 0.0 0.0035 17.2 0.0 1.7 2 0 0 2 2 2 1 SCO1/SenC HIT PF01230.23 EEQ39469.1 - 2.4e-23 82.7 0.0 3.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EEQ39469.1 - 0.0024 18.3 0.1 0.0037 17.7 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EEQ39469.1 - 0.02 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Med6 PF04934.14 EEQ39470.1 - 1.2e-50 170.8 2.2 1.6e-50 170.4 2.2 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Pro_isomerase PF00160.21 EEQ39472.1 - 8.1e-45 152.9 0.2 1.1e-44 152.5 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RNase_H_2 PF13482.6 EEQ39472.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 RNase_H superfamily IGR PF09597.10 EEQ39473.1 - 5.2e-20 71.3 0.2 1.1e-19 70.3 0.2 1.5 1 0 0 1 1 1 1 IGR protein motif FAM110_C PF14160.6 EEQ39473.1 - 0.06 14.4 0.5 0.14 13.2 0.5 1.8 1 1 0 1 1 1 0 Centrosome-associated C terminus Orbi_VP4 PF05059.12 EEQ39473.1 - 0.066 11.2 0.1 0.15 10.0 0.1 1.3 1 1 0 1 1 1 0 Orbivirus VP4 core protein Ligase_CoA PF00549.19 EEQ39475.1 - 1.4e-25 89.9 0.0 2.6e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 EEQ39475.1 - 4.2e-25 88.3 2.1 4.2e-25 88.3 2.1 1.9 2 0 0 2 2 2 1 CoA binding domain Succ_CoA_lig PF13607.6 EEQ39475.1 - 2.2e-06 27.5 0.0 4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EEQ39475.1 - 0.0011 19.4 0.1 0.0028 18.1 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain Actin PF00022.19 EEQ39476.1 - 4.3e-22 78.3 0.0 2.6e-16 59.3 0.0 3.7 3 1 0 3 3 3 2 Actin Actin_micro PF17003.5 EEQ39476.1 - 5.1e-10 39.1 0.7 3e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 EEQ39476.1 - 2.6e-07 29.8 0.0 3.7e-05 22.7 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EEQ39476.1 - 0.0072 16.7 0.1 0.015 15.7 0.0 1.7 1 1 0 1 1 1 1 Cell division protein FtsA DUF3246 PF11596.8 EEQ39476.1 - 0.016 14.7 1.4 0.016 14.7 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Capsid-VNN PF11729.8 EEQ39476.1 - 0.04 12.9 0.6 0.072 12.1 0.6 1.3 1 0 0 1 1 1 0 nodavirus capsid protein DUF1151 PF06625.11 EEQ39477.1 - 0.031 14.2 1.4 0.085 12.8 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) Occludin_ELL PF07303.13 EEQ39477.1 - 2.7 8.8 7.9 1.1 10.1 3.4 2.3 1 1 1 2 2 2 0 Occludin homology domain Svf1_C PF17187.4 EEQ39478.1 - 1.7e-62 210.1 2.2 1.7e-62 210.1 2.2 1.6 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EEQ39478.1 - 1.4e-61 207.3 0.4 4.4e-61 205.7 0.0 1.9 2 0 0 2 2 2 1 Svf1-like N-terminal lipocalin domain ABC2_membrane PF01061.24 EEQ39479.1 - 5.6e-37 127.2 13.7 5.6e-37 127.2 13.7 1.9 3 0 0 3 3 2 1 ABC-2 type transporter ABC_tran PF00005.27 EEQ39479.1 - 2.4e-27 96.1 0.0 4.2e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EEQ39479.1 - 7.5e-05 22.0 17.8 7.5e-05 22.0 17.8 2.0 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.6 EEQ39479.1 - 0.00012 22.0 0.1 0.18 11.6 0.0 2.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ39479.1 - 0.0029 17.1 0.0 0.013 15.0 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EEQ39479.1 - 0.0059 16.5 0.3 0.02 14.8 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EEQ39479.1 - 0.026 14.3 0.3 0.065 13.0 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EEQ39479.1 - 0.062 13.5 0.1 0.14 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ39479.1 - 0.095 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EEQ39479.1 - 0.095 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Laminin_EGF PF00053.24 EEQ39479.1 - 7.3 6.8 32.5 0.11 12.7 8.1 3.7 2 2 1 3 3 2 0 Laminin EGF domain UCH PF00443.29 EEQ39480.1 - 4.8e-48 163.9 1.3 8.9e-48 163.0 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 EEQ39480.1 - 9.7e-47 156.7 18.2 6e-15 54.9 0.3 5.2 5 0 0 5 5 5 4 A repeated domain in UCH-protein UCH_1 PF13423.6 EEQ39480.1 - 4e-05 23.4 6.3 0.00066 19.4 6.3 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LOH1CR12 PF10158.9 EEQ39480.1 - 0.058 13.4 0.4 0.3 11.1 0.4 2.2 1 0 0 1 1 1 0 Tumour suppressor protein P53_tetramer PF07710.11 EEQ39480.1 - 0.079 12.3 0.2 0.24 10.8 0.2 1.8 1 0 0 1 1 1 0 P53 tetramerisation motif SPAM PF02090.15 EEQ39480.1 - 0.23 11.2 1.9 0.48 10.2 1.9 1.4 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein BCS1_N PF08740.11 EEQ39481.1 - 2.9e-47 161.1 0.0 4.4e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EEQ39481.1 - 2.9e-22 79.5 0.0 5e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EEQ39481.1 - 0.001 18.3 0.0 0.002 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EEQ39481.1 - 0.0016 18.8 0.0 0.0085 16.5 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EEQ39481.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EEQ39481.1 - 0.0056 16.7 0.0 0.023 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ39481.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEQ39481.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EEQ39481.1 - 0.014 15.9 0.0 0.026 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ39481.1 - 0.023 15.2 0.0 0.045 14.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EEQ39481.1 - 0.055 13.7 0.0 0.29 11.4 0.0 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ39481.1 - 0.056 13.8 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EEQ39481.1 - 0.073 13.0 0.0 0.52 10.2 0.0 2.1 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 EEQ39481.1 - 0.091 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EEQ39481.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EEQ39481.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EEQ39481.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 EEQ39481.1 - 0.19 11.9 0.0 0.4 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gram_pos_anchor PF00746.21 EEQ39481.1 - 0.22 11.5 1.0 0.47 10.4 1.0 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif AAA_11 PF13086.6 EEQ39481.1 - 0.23 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain HSF_DNA-bind PF00447.17 EEQ39482.1 - 2e-29 102.1 2.1 4.1e-29 101.0 2.1 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Tcp11 PF05794.13 EEQ39484.1 - 9.3e-138 460.0 0.4 1.4e-137 459.4 0.4 1.3 1 0 0 1 1 1 1 T-complex protein 11 HIG_1_N PF04588.13 EEQ39487.1 - 6.5e-18 64.7 0.4 8.9e-18 64.3 0.4 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Mt_ATP-synt_B PF05405.14 EEQ39487.1 - 0.0064 16.1 4.3 0.011 15.4 4.3 1.4 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3619 PF12279.8 EEQ39487.1 - 0.18 12.1 2.9 0.94 9.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) DUF4199 PF13858.6 EEQ39487.1 - 1 9.7 4.2 3.6 7.9 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) ChAPs PF09295.10 EEQ39488.1 - 8.3e-129 430.0 1.1 1.1e-128 429.6 1.1 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 EEQ39488.1 - 4e-06 27.3 0.1 0.00016 22.1 0.0 2.7 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ39488.1 - 0.0012 18.8 0.5 1.5 9.1 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ39488.1 - 0.002 18.3 1.7 0.13 12.5 0.8 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EEQ39488.1 - 0.0037 17.3 0.2 7.6 7.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ39488.1 - 0.12 13.2 0.3 36 5.6 0.1 3.8 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ39488.1 - 0.13 13.0 0.1 0.66 10.7 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ39488.1 - 0.14 12.1 0.3 15 5.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIID-31kDa PF02291.15 EEQ39489.1 - 8.8e-49 164.6 0.0 1.1e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit TPK_catalytic PF04263.16 EEQ39490.1 - 4.4e-36 123.6 0.0 6.1e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EEQ39490.1 - 2.7e-10 39.8 0.1 4.9e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF1713 PF08213.11 EEQ39491.1 - 2.8e-12 46.3 22.2 4.5e-12 45.7 22.2 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Ham1p_like PF01725.16 EEQ39492.1 - 6.9e-57 192.4 0.0 7.8e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Kelch_6 PF13964.6 EEQ39492.1 - 0.05 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Kelch motif DUF3602 PF12223.8 EEQ39493.1 - 5.2e-27 94.3 16.8 1.9e-18 66.9 1.8 3.8 1 1 3 4 4 4 4 Protein of unknown function (DUF3602) Fcf1 PF04900.12 EEQ39495.1 - 1.8e-35 121.3 0.7 2.8e-35 120.7 0.7 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 EEQ39495.1 - 2.4e-14 53.6 0.0 3.4e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 EEQ39495.1 - 0.021 15.1 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 NTF2 fold immunity protein UBA PF00627.31 EEQ39496.1 - 9.4e-09 35.0 0.1 2.2e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Importin_rep_6 PF18829.1 EEQ39496.1 - 0.39 10.9 6.9 0.17 12.0 2.0 2.8 2 1 0 2 2 2 0 Importin repeat 6 tRNA-synt_1d PF00750.19 EEQ39497.1 - 3.8e-118 394.4 6.5 5.1e-118 394.0 6.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EEQ39497.1 - 2.9e-28 98.4 0.3 6.5e-28 97.3 0.3 1.6 1 0 0 1 1 1 1 DALR anticodon binding domain POT1 PF02765.17 EEQ39497.1 - 0.0036 17.1 0.1 0.091 12.6 0.0 2.5 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 DUF4393 PF14337.6 EEQ39497.1 - 0.0076 16.1 0.6 0.25 11.1 0.0 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4393) Arg_tRNA_synt_N PF03485.16 EEQ39497.1 - 0.035 14.7 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain DUF5631 PF18645.1 EEQ39497.1 - 0.15 12.5 0.0 6.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5631) PINIT PF14324.6 EEQ39498.1 - 1.3e-22 80.7 0.7 8.4e-22 78.1 0.0 2.4 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 EEQ39498.1 - 9.3e-22 76.5 3.3 1.7e-21 75.7 3.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 EEQ39498.1 - 2.8e-12 46.1 0.7 5.1e-12 45.2 0.7 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 EEQ39498.1 - 1.1e-10 41.2 0.5 2.4e-10 40.1 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rho_N PF07498.12 EEQ39498.1 - 0.034 14.1 0.5 0.068 13.1 0.5 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain zf-C3HC4_2 PF13923.6 EEQ39498.1 - 0.76 9.7 2.5 1.5 8.7 2.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) S1 PF00575.23 EEQ39499.1 - 3.3e-17 62.6 0.1 4.9e-17 62.0 0.1 1.3 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 EEQ39499.1 - 1.3e-09 38.3 0.1 2.4e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 EEQ39499.1 - 0.09 13.0 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 Ribosomal_L13 PF00572.18 EEQ39500.1 - 9.1e-46 155.2 0.1 1.4e-45 154.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.28 EEQ39501.1 - 3.1e-125 418.3 0.0 4.8e-125 417.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 EEQ39501.1 - 1.3e-34 118.4 0.2 2.5e-34 117.5 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EEQ39501.1 - 8.8e-26 90.0 0.5 2.1e-25 88.8 0.5 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EEQ39501.1 - 1.4e-24 86.0 0.1 3.2e-24 84.9 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EEQ39501.1 - 1.9e-23 82.8 2.3 1.9e-23 82.7 0.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_1 PF04563.15 EEQ39501.1 - 1.4e-08 34.5 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EEQ39501.1 - 1.4e-06 28.1 0.3 3.1e-06 27.0 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 MRNIP PF15749.5 EEQ39501.1 - 0.0078 16.9 0.2 0.021 15.5 0.2 1.7 1 0 0 1 1 1 1 MRN-interacting protein RNA_pol_Rpb2_45 PF10385.9 EEQ39501.1 - 0.2 11.9 0.5 4.4 7.6 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase beta subunit external 1 domain RNA_pol_Rpb2_1 PF04563.15 EEQ39502.1 - 1.5e-56 191.1 0.1 1.8e-56 190.9 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EEQ39502.1 - 1.5e-30 106.2 0.0 3.2e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 PIF6 PF05341.11 EEQ39502.1 - 0.094 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 Per os infectivity factor 6 Ribosomal_L23 PF00276.20 EEQ39503.1 - 5.1e-11 42.8 1.0 1.6e-10 41.2 0.0 2.3 3 0 0 3 3 3 1 Ribosomal protein L23 TB2_DP1_HVA22 PF03134.19 EEQ39504.1 - 2.6e-09 36.9 1.2 7.5e-09 35.4 0.2 2.2 3 0 0 3 3 3 1 TB2/DP1, HVA22 family HMA PF00403.26 EEQ39505.1 - 2e-15 57.0 1.3 2.3e-15 56.8 1.3 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain DUF211 PF02680.14 EEQ39505.1 - 0.04 14.1 0.3 0.05 13.8 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Dsl1_C PF11989.8 EEQ39506.1 - 1.1e-19 70.9 8.6 1.1e-19 70.9 8.6 2.0 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal CENP-X PF09415.10 EEQ39506.1 - 0.055 13.8 0.2 0.45 10.9 0.0 2.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X PrkA PF06798.12 EEQ39506.1 - 0.12 12.0 5.8 0.068 12.8 2.2 2.4 2 1 0 2 2 2 0 PrkA serine protein kinase C-terminal domain Nop14 PF04147.12 EEQ39506.1 - 0.61 8.2 20.1 0.17 10.0 14.3 2.1 2 0 0 2 2 2 0 Nop14-like family SDA1 PF05285.12 EEQ39506.1 - 1.6 8.1 21.9 3 7.2 21.9 1.4 1 0 0 1 1 1 0 SDA1 MnmE_helical PF12631.7 EEQ39506.1 - 3.7 7.7 11.2 0.84 9.8 4.2 3.1 2 2 0 2 2 2 0 MnmE helical domain COPI_C PF06957.11 EEQ39506.1 - 9.9 4.8 16.7 19 3.9 16.7 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PTPA PF03095.15 EEQ39508.1 - 0.018 14.5 0.3 0.018 14.5 0.3 2.8 1 1 2 3 3 3 0 Phosphotyrosyl phosphate activator (PTPA) protein Kre28 PF17097.5 EEQ39508.1 - 0.048 12.6 23.4 12 4.7 23.4 3.3 1 1 0 1 1 1 0 Spindle pole body component GLE1 PF07817.13 EEQ39508.1 - 0.049 12.8 1.8 0.14 11.3 0.2 2.1 1 1 1 2 2 2 0 GLE1-like protein DUF3037 PF11236.8 EEQ39508.1 - 0.41 11.1 2.6 3.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3037) DUF1465 PF07323.12 EEQ39508.1 - 0.41 10.5 7.2 0.21 11.4 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1465) BLOC1_2 PF10046.9 EEQ39508.1 - 0.42 10.9 16.3 0.44 10.9 4.6 3.6 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SMAP PF15477.6 EEQ39508.1 - 0.82 10.7 3.9 0.71 10.9 0.4 2.6 3 1 0 3 3 3 0 Small acidic protein family SlyX PF04102.12 EEQ39508.1 - 2.2 9.0 11.0 2.5 8.8 2.1 3.4 3 0 0 3 3 3 0 SlyX EMP24_GP25L PF01105.24 EEQ39508.1 - 2.3 8.1 7.8 10 6.1 0.3 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF1664 PF07889.12 EEQ39508.1 - 3.7 7.6 11.8 3.7 7.6 1.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 EEQ39508.1 - 4.3 7.7 11.2 2.9 8.2 1.8 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF16 PF01519.16 EEQ39508.1 - 5.9 7.4 15.5 1.6 9.3 3.7 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Hydrolase_6 PF13344.6 EEQ39509.1 - 2.4e-19 69.3 0.0 4.7e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ39509.1 - 4.6e-14 52.2 0.0 3.6e-13 49.4 0.0 2.6 2 1 0 2 2 2 1 HAD-hyrolase-like Casc1_N PF15927.5 EEQ39509.1 - 0.012 15.3 0.4 0.021 14.5 0.4 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF3402 PF11882.8 EEQ39510.1 - 1.4e-81 275.0 13.5 1.3e-79 268.5 13.5 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EEQ39510.1 - 4.6e-42 144.2 4.4 9.9e-38 130.0 1.2 2.3 1 1 0 2 2 2 2 N1221-like protein Tom22 PF04281.13 EEQ39511.1 - 2.1e-48 163.6 1.2 2.4e-48 163.4 1.2 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 CDP-OH_P_transf PF01066.21 EEQ39512.1 - 3.1e-16 59.9 0.1 3.1e-16 59.9 0.1 3.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase AD PF09793.9 EEQ39513.1 - 3.4e-18 65.6 0.8 7.1e-18 64.5 0.8 1.5 1 1 0 1 1 1 1 Anticodon-binding domain DSPc PF00782.20 EEQ39514.1 - 4.9e-10 39.3 0.0 8.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEQ39514.1 - 4.5e-05 23.1 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EEQ39514.1 - 0.00054 19.7 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Med28 PF11594.8 EEQ39514.1 - 0.032 14.3 0.0 0.061 13.4 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 Y_phosphatase3 PF13350.6 EEQ39514.1 - 0.057 13.4 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family TPR_2 PF07719.17 EEQ39515.1 - 2e-26 89.9 36.6 0.0017 18.3 0.2 11.1 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ39515.1 - 8.1e-24 82.4 33.5 0.00012 21.8 0.3 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ39515.1 - 2.1e-19 69.9 14.0 6.8e-08 33.0 0.2 6.3 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ39515.1 - 4.3e-18 63.9 29.2 0.013 15.6 0.1 10.4 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ39515.1 - 1.1e-14 54.6 19.8 0.00014 22.3 0.1 6.5 4 3 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ39515.1 - 1.8e-14 53.0 4.6 0.096 13.1 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ39515.1 - 1.5e-13 50.8 23.2 0.0022 18.2 1.8 7.9 5 4 2 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ39515.1 - 1e-12 47.5 34.2 3e-06 26.8 0.3 8.1 7 1 2 9 9 9 4 TPR repeat TPR_14 PF13428.6 EEQ39515.1 - 5.8e-10 39.2 16.4 0.036 14.9 0.1 8.2 6 4 3 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ39515.1 - 1.9e-08 34.4 19.4 0.0093 16.2 0.0 5.0 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EEQ39515.1 - 2e-08 34.0 0.7 1.1e-06 28.2 0.6 2.4 1 1 1 2 2 2 2 MalT-like TPR region TPR_21 PF09976.9 EEQ39515.1 - 3.1e-05 23.8 17.1 0.011 15.4 2.9 4.9 4 1 1 5 5 5 2 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 EEQ39515.1 - 6.8e-05 22.9 3.1 3 8.1 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EEQ39515.1 - 0.00071 19.9 0.9 6.2 7.2 0.1 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EEQ39515.1 - 0.0013 18.7 3.4 0.15 12.1 0.1 5.0 5 0 0 5 5 4 1 Exonuclease VII small subunit MHC2-interact PF09307.10 EEQ39515.1 - 0.024 14.6 0.1 0.061 13.3 0.1 1.6 1 0 0 1 1 1 0 CLIP, MHC2 interacting SHNi-TPR PF10516.9 EEQ39515.1 - 0.027 13.9 3.4 3.3 7.2 0.1 4.8 5 0 0 5 5 5 0 SHNi-TPR ANAPC5 PF12862.7 EEQ39515.1 - 0.066 13.3 1.5 24 5.1 0.0 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 HrpB1_HrpK PF09613.10 EEQ39515.1 - 0.11 12.1 0.7 4.2 7.0 0.1 3.0 2 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 EEQ39515.1 - 0.12 12.6 0.8 43 4.7 0.0 4.2 4 0 0 4 4 3 0 PPR repeat BTAD PF03704.17 EEQ39515.1 - 0.16 12.4 4.9 2 8.9 0.9 3.8 2 2 1 3 3 3 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EEQ39515.1 - 0.21 12.3 15.7 21 6.0 0.0 7.5 9 0 0 9 9 7 0 Tetratricopeptide repeat SpoIIIAH PF12685.7 EEQ39515.1 - 0.36 10.6 8.1 0.084 12.7 3.5 2.2 2 1 0 2 2 2 0 SpoIIIAH-like protein TPR_10 PF13374.6 EEQ39515.1 - 0.74 9.8 12.4 5.5 7.0 0.1 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4810 PF16068.5 EEQ39515.1 - 1.9 9.1 7.1 17 6.0 0.1 4.3 3 1 2 5 5 3 0 Domain of unknown function (DUF4810) Arrestin_N PF00339.29 EEQ39516.1 - 1.4e-13 51.1 12.3 2e-10 40.9 0.1 3.7 4 0 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EEQ39516.1 - 0.048 13.1 0.1 0.048 13.1 0.1 2.8 3 0 0 3 3 3 0 Bul1 C terminus LDB19 PF13002.7 EEQ39516.1 - 0.12 12.1 0.8 2.8 7.6 0.0 3.0 2 1 1 3 3 3 0 Arrestin_N terminal like V-set_2 PF15910.5 EEQ39516.1 - 0.17 12.0 0.9 0.5 10.5 0.2 2.0 2 0 0 2 2 2 0 ICOS V-set domain FKBP_C PF00254.28 EEQ39517.1 - 2.7e-33 114.2 0.0 3.5e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Foie-gras_1 PF11817.8 EEQ39518.1 - 8.5e-16 58.3 0.7 7.5e-14 51.9 0.0 2.5 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun PF07919.12 EEQ39518.1 - 0.0002 20.3 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi FeS_assembly_P PF01883.19 EEQ39519.1 - 4e-09 36.5 0.0 9e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein DUF3871 PF12987.7 EEQ39519.1 - 0.12 11.2 0.1 0.44 9.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3871) Pullulanase_Ins PF18494.1 EEQ39521.1 - 0.09 13.3 0.2 0.24 11.9 0.0 1.7 2 0 0 2 2 2 0 Pullulanase Ins domain NT-C2 PF10358.9 EEQ39522.1 - 2.1e-39 134.6 0.6 3.9e-39 133.7 0.6 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3658 PF12395.8 EEQ39523.1 - 0.058 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function LSM PF01423.22 EEQ39524.1 - 6.7e-18 64.1 1.2 7.2e-18 64.0 1.2 1.0 1 0 0 1 1 1 1 LSM domain Myosin_N PF02736.19 EEQ39524.1 - 0.059 13.2 0.2 0.13 12.1 0.1 1.6 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain Glycogen_syn PF05693.13 EEQ39525.1 - 0 1127.7 0.0 0 1127.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EEQ39525.1 - 1.6e-06 27.7 0.0 0.0001 21.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ39525.1 - 5.9e-06 26.8 0.0 0.0027 18.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEQ39525.1 - 7.8e-06 26.4 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EEQ39525.1 - 8.5e-06 25.9 0.4 1.6e-05 25.0 0.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 EEQ39525.1 - 4.7e-05 23.2 0.2 0.00011 21.9 0.1 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain WD40 PF00400.32 EEQ39526.1 - 2.5e-41 138.8 11.5 6.2e-07 30.0 0.1 11.4 13 0 0 13 13 12 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39526.1 - 9.2e-24 83.6 0.0 0.006 16.8 0.0 9.0 3 2 6 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EEQ39526.1 - 8.4e-21 74.3 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 EEQ39526.1 - 1.9e-05 23.8 3.1 0.23 10.4 0.0 5.7 4 3 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EEQ39526.1 - 8.2e-05 21.8 0.7 0.017 14.2 0.0 3.5 2 2 1 3 3 3 1 Coatomer WD associated region Nup160 PF11715.8 EEQ39526.1 - 0.00021 20.1 6.0 0.48 9.0 0.0 4.3 1 1 1 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EEQ39526.1 - 0.0004 19.3 1.2 1.3 7.7 0.1 4.2 2 2 1 4 4 4 2 Nup133 N terminal like Nbas_N PF15492.6 EEQ39526.1 - 0.0013 18.2 1.3 2.9 7.1 0.0 4.3 3 1 2 5 5 5 2 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 EEQ39526.1 - 0.0037 17.2 0.0 0.023 14.7 0.0 2.5 1 0 0 1 1 1 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EEQ39526.1 - 0.0087 14.6 0.1 2.3 6.7 0.0 2.9 3 0 0 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.6 EEQ39526.1 - 0.033 13.8 1.3 1.9 8.0 0.3 2.7 2 1 0 3 3 3 0 PQQ-like domain MPP6 PF10175.9 EEQ39527.1 - 8.8e-14 52.1 7.4 1.4e-13 51.5 7.4 1.4 1 1 0 1 1 1 1 M-phase phosphoprotein 6 BshC PF10079.9 EEQ39527.1 - 0.00012 21.0 0.3 0.00015 20.7 0.3 1.0 1 0 0 1 1 1 1 Bacillithiol biosynthesis BshC Utp14 PF04615.13 EEQ39527.1 - 0.11 11.0 8.1 0.19 10.3 8.1 1.4 1 1 0 1 1 1 0 Utp14 protein UPF0029 PF01205.19 EEQ39528.1 - 1.6e-13 50.9 0.3 9.2e-13 48.5 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EEQ39528.1 - 5.1e-09 36.4 1.2 2.5e-08 34.2 1.2 2.2 1 1 0 1 1 1 1 RWD domain QueC PF06508.13 EEQ39528.1 - 0.0038 16.8 0.2 0.0076 15.8 0.2 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC DUF883 PF05957.13 EEQ39528.1 - 0.3 11.7 2.3 2.9 8.6 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Glucan_synthase PF02364.15 EEQ39529.1 - 6.9e-119 398.3 15.2 9.9e-119 397.8 15.2 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component Glucan_synthase PF02364.15 EEQ39530.1 - 8.1e-180 599.8 0.0 8.1e-180 599.8 0.0 2.1 3 0 0 3 3 3 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EEQ39530.1 - 1.1e-34 119.6 3.4 9.6e-34 116.5 3.4 2.4 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Peptidase_S8 PF00082.22 EEQ39531.1 - 5.3e-31 108.0 9.9 1.5e-30 106.5 9.9 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 EEQ39531.1 - 9.2e-07 29.4 0.0 2.1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 ACC_central PF08326.12 EEQ39532.1 - 4.4e-265 881.5 0.3 5.6e-265 881.1 0.3 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EEQ39532.1 - 4e-182 606.3 0.0 5.7e-182 605.8 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EEQ39532.1 - 3.5e-51 173.7 0.0 8.1e-51 172.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EEQ39532.1 - 2e-28 99.2 0.1 4.1e-28 98.1 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EEQ39532.1 - 2e-22 79.3 0.0 3.9e-21 75.2 0.0 2.6 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EEQ39532.1 - 1.6e-18 66.3 0.4 3.8e-18 65.1 0.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EEQ39532.1 - 0.0023 18.0 0.0 0.0098 16.0 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EEQ39532.1 - 0.02 14.7 0.1 9 6.2 0.1 2.6 2 0 0 2 2 2 0 Biotin-lipoyl like GxGYxYP_N PF16216.5 EEQ39532.1 - 0.029 14.5 0.0 0.075 13.2 0.0 1.6 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal PDEase_II PF02112.15 EEQ39532.1 - 0.039 13.1 0.1 0.071 12.2 0.1 1.3 1 0 0 1 1 1 0 cAMP phosphodiesterases class-II Dala_Dala_lig_C PF07478.13 EEQ39532.1 - 0.042 13.4 0.0 0.2 11.1 0.0 2.2 3 0 0 3 3 3 0 D-ala D-ala ligase C-terminus RnfC_N PF13375.6 EEQ39532.1 - 0.077 13.0 0.1 0.25 11.3 0.1 1.9 2 0 0 2 2 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_Ter PF15632.6 EEQ39532.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Spore_III_AB PF09548.10 EEQ39532.1 - 0.2 11.7 1.1 0.6 10.2 1.1 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Sugar_tr PF00083.24 EEQ39533.1 - 1.5e-104 350.4 17.3 1.8e-104 350.1 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ39533.1 - 3.9e-24 85.3 16.4 7.7e-18 64.5 3.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ39533.1 - 6.9e-05 21.6 11.5 0.02 13.5 1.0 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EEQ39533.1 - 0.038 12.4 5.8 0.011 14.2 0.8 2.0 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EEQ39533.1 - 2.1 6.5 10.5 0.075 11.3 1.4 2.6 3 1 1 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Tim17 PF02466.19 EEQ39534.1 - 3.1e-28 98.4 0.8 4.2e-28 97.9 0.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dus PF01207.17 EEQ39535.1 - 1.3e-50 172.3 0.0 3.6e-50 170.8 0.0 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) COX5A PF02284.16 EEQ39535.1 - 0.018 15.0 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va TMP-TENI PF02581.17 EEQ39535.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 2 0 0 2 2 2 0 Thiamine monophosphate synthase SWIRM PF04433.17 EEQ39536.1 - 4e-10 39.9 0.0 1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain DMAP_binding PF06464.11 EEQ39536.1 - 0.71 10.7 7.0 0.17 12.7 3.2 1.9 2 0 0 2 2 2 0 DMAP1-binding Domain Mis12 PF05859.12 EEQ39538.1 - 3.1e-41 140.6 0.2 8.6e-41 139.2 0.1 1.8 2 0 0 2 2 2 1 Mis12 protein Casc1_N PF15927.5 EEQ39538.1 - 0.35 10.5 1.6 1 9.0 0.7 1.9 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus RPA43_OB PF17875.1 EEQ39540.1 - 5.7e-29 101.2 0.2 1.6e-28 99.8 0.2 1.8 1 0 0 1 1 1 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EEQ39540.1 - 4.6e-12 46.1 0.0 8.3e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CorA PF01544.18 EEQ39541.1 - 3.1e-06 26.7 4.0 1e-05 25.0 3.8 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribonuclease_T2 PF00445.18 EEQ39541.1 - 0.0035 17.6 0.1 2.4 8.4 0.1 2.6 1 1 1 2 2 2 2 Ribonuclease T2 family vATP-synt_E PF01991.18 EEQ39542.1 - 5.3e-59 199.0 16.8 6e-59 198.8 16.8 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit ThuA PF06283.11 EEQ39542.1 - 0.21 11.8 0.4 0.39 10.9 0.4 1.4 1 0 0 1 1 1 0 Trehalose utilisation PHA_gran_rgn PF09650.10 EEQ39542.1 - 0.25 11.6 3.6 0.36 11.1 0.2 2.4 2 0 0 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) RhoGEF67_u2 PF16614.5 EEQ39542.1 - 2.9 8.0 6.0 24 5.1 2.2 2.2 2 0 0 2 2 2 0 Unstructured region two on RhoGEF 6 and 7 Mito_carr PF00153.27 EEQ39543.1 - 1e-56 188.8 6.8 2.5e-19 69.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GCP_N_terminal PF17681.1 EEQ39544.1 - 2.8e-34 119.1 1.4 6e-34 118.1 1.4 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EEQ39544.1 - 4.1e-27 95.5 3.3 8.7e-27 94.4 0.9 2.5 3 1 0 3 3 3 1 Gamma tubulin complex component C-terminal DUF3046 PF11248.8 EEQ39544.1 - 0.2 12.0 0.0 0.47 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3046) Aminotran_1_2 PF00155.21 EEQ39545.1 - 1.7e-75 254.5 0.0 2.2e-75 254.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEQ39545.1 - 5.4e-06 25.2 0.0 8.8e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EEQ39545.1 - 0.00023 20.5 0.0 0.00055 19.3 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EEQ39545.1 - 0.00068 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EEQ39545.1 - 0.0008 18.8 0.7 0.0057 16.0 0.7 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Preseq_ALAS PF09029.10 EEQ39545.1 - 0.015 15.8 0.5 0.03 14.8 0.5 1.5 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence BATS PF06968.13 EEQ39546.1 - 1.5e-23 82.7 0.1 3.5e-23 81.6 0.1 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EEQ39546.1 - 8.3e-17 62.1 0.1 5.5e-16 59.4 0.2 1.9 2 0 0 2 2 2 1 Radical SAM superfamily INPP5B_PH PF16776.5 EEQ39546.1 - 0.0031 17.2 0.0 0.0094 15.7 0.0 1.8 2 0 0 2 2 2 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain Lectin_C_term PF18022.1 EEQ39546.1 - 0.17 12.4 0.0 0.39 11.2 0.0 1.5 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin C-terminal domain FAD-oxidase_C PF02913.19 EEQ39547.1 - 3.8e-50 170.9 0.0 5.3e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EEQ39547.1 - 7.8e-37 126.1 0.1 1.6e-36 125.1 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain CCDC53 PF10152.9 EEQ39548.1 - 0.00062 20.2 3.8 0.00062 20.2 3.8 1.9 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex DUF4407 PF14362.6 EEQ39548.1 - 0.0064 15.9 2.6 0.01 15.2 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) UPF0172 PF03665.13 EEQ39548.1 - 0.013 15.6 2.2 0.028 14.5 2.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) MecA PF05389.12 EEQ39548.1 - 0.032 13.9 7.3 0.028 14.0 3.7 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Spt20 PF12090.8 EEQ39548.1 - 0.098 12.3 35.5 0.032 13.8 26.0 2.4 2 0 0 2 2 2 0 Spt20 family SprA-related PF12118.8 EEQ39548.1 - 0.46 9.6 16.2 0.096 11.8 11.7 1.9 2 0 0 2 2 2 0 SprA-related family FAM60A PF15396.6 EEQ39548.1 - 2.8 7.9 7.3 0.56 10.2 3.6 1.8 2 0 0 2 2 2 0 Protein Family FAM60A zf-RING_2 PF13639.6 EEQ39549.1 - 1.5e-10 41.3 4.1 8.7e-10 38.8 4.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EEQ39549.1 - 8.5e-08 32.4 4.7 2.6e-07 30.8 4.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EEQ39549.1 - 4.2e-05 23.5 0.5 9.1e-05 22.4 0.5 1.6 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EEQ39549.1 - 0.00011 21.9 2.4 0.026 14.4 1.0 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EEQ39549.1 - 0.00029 20.5 0.7 0.00079 19.1 0.7 1.8 1 1 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EEQ39549.1 - 0.00034 20.4 6.1 0.0086 15.9 6.8 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ39549.1 - 0.00049 19.9 2.0 0.0017 18.2 2.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 EEQ39549.1 - 0.0028 17.4 1.2 0.87 9.5 0.3 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 EEQ39549.1 - 0.0068 16.4 2.2 0.018 15.1 2.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EEQ39549.1 - 0.0076 16.4 1.7 0.013 15.6 1.7 1.4 1 0 0 1 1 1 1 RING-variant domain zf-C2H2_9 PF16293.5 EEQ39549.1 - 0.012 15.5 1.0 4.1 7.3 0.0 2.9 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-RING_5 PF14634.6 EEQ39549.1 - 0.044 13.7 1.1 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Cwf_Cwc_15 PF04889.12 EEQ39549.1 - 0.057 13.1 5.2 0.093 12.4 5.2 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-C3HC4_3 PF13920.6 EEQ39549.1 - 0.059 13.2 4.1 1.3 8.9 4.3 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CTU2 PF10288.9 EEQ39549.1 - 0.11 12.8 2.2 0.73 10.1 2.2 2.1 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-Di19 PF05605.12 EEQ39549.1 - 0.12 12.7 1.1 16 5.9 0.4 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 EEQ39549.1 - 0.18 12.1 0.7 6.1 7.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon Prok-RING_1 PF14446.6 EEQ39549.1 - 0.18 11.7 1.6 6.5 6.8 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_S10 PF00338.22 EEQ39550.1 - 2.6e-19 69.2 0.3 1e-18 67.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e FtsJ PF01728.19 EEQ39551.1 - 2.8e-71 239.3 0.0 3.9e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EEQ39551.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_2 PF00152.20 EEQ39552.1 - 1.9e-77 260.4 1.6 2.1e-77 260.3 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EEQ39552.1 - 1.9e-10 40.5 0.1 4e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EEQ39552.1 - 2.5e-07 30.4 0.1 0.0042 16.6 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) JAB PF01398.21 EEQ39553.1 - 5.6e-05 23.1 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease TFR_dimer PF04253.15 EEQ39553.1 - 0.018 15.2 0.5 0.034 14.3 0.5 1.5 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain His_Phos_1 PF00300.22 EEQ39554.1 - 5.7e-19 68.6 0.0 1.3e-18 67.4 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) KxDL PF10241.9 EEQ39554.1 - 0.022 15.0 2.7 0.05 13.9 2.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein TIM PF00121.18 EEQ39555.1 - 4.1e-87 291.6 0.1 4.6e-87 291.4 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase TatD_DNase PF01026.21 EEQ39556.1 - 3.1e-34 118.5 0.8 4e-34 118.1 0.8 1.1 1 0 0 1 1 1 1 TatD related DNase FRB_dom PF08771.11 EEQ39556.1 - 0.086 13.3 0.1 13 6.2 0.0 2.5 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Glyco_transf_20 PF00982.21 EEQ39557.1 - 1.3e-144 482.4 0.5 1.9e-144 481.9 0.5 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEQ39557.1 - 8.7e-14 51.2 0.3 2.2e-13 49.9 0.0 1.9 2 1 0 2 2 2 1 Trehalose-phosphatase DUF3971 PF13116.6 EEQ39557.1 - 0.058 13.0 0.1 0.09 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function CTK3 PF12243.8 EEQ39558.1 - 5.6e-33 113.6 2.9 1e-32 112.7 2.9 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EEQ39558.1 - 8.7e-21 73.9 0.4 2e-20 72.7 0.4 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Peptidase_M91 PF14891.6 EEQ39558.1 - 0.055 13.8 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 Effector protein ICAM_N PF03921.14 EEQ39558.1 - 0.072 12.8 0.2 1.3 8.8 0.2 2.3 1 1 1 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain eIF-1a PF01176.19 EEQ39559.1 - 6.6e-20 70.7 0.1 9.3e-20 70.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DAGK_acc PF00609.19 EEQ39559.1 - 0.05 13.9 0.0 0.075 13.4 0.0 1.2 1 0 0 1 1 1 0 Diacylglycerol kinase accessory domain DSPc PF00782.20 EEQ39560.1 - 1.9e-22 79.5 0.1 4.5e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain DSPn PF14671.6 EEQ39560.1 - 1.9e-10 41.4 0.0 1.8e-09 38.1 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half Y_phosphatase PF00102.27 EEQ39560.1 - 4.8e-05 23.0 0.7 8.1e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EEQ39560.1 - 0.021 15.0 0.0 0.16 12.1 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Mucin PF01456.17 EEQ39560.1 - 0.56 10.2 14.5 0.9 9.5 13.4 1.7 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 EEQ39560.1 - 5.3 7.0 9.1 24 4.9 8.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Complex1_LYR_2 PF13233.6 EEQ39561.1 - 0.0098 16.6 1.1 0.053 14.3 0.0 2.7 2 2 0 2 2 2 1 Complex1_LYR-like HXXSHH PF07586.11 EEQ39561.1 - 0.029 14.0 0.4 0.057 13.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) RPAP2_Rtr1 PF04181.13 EEQ39562.1 - 6.7e-23 80.8 2.6 1.1e-22 80.2 2.6 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF747 PF05346.11 EEQ39563.1 - 2.4e-92 309.8 12.6 2.4e-92 309.8 12.6 1.6 2 0 0 2 2 2 1 Eukaryotic membrane protein family COX15-CtaA PF02628.15 EEQ39564.1 - 7.9e-116 386.6 1.1 9.5e-116 386.4 1.1 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Fumarate_red_C PF02300.17 EEQ39564.1 - 0.036 14.2 0.8 0.39 10.8 0.4 2.5 2 0 0 2 2 2 0 Fumarate reductase subunit C Cytochrom_B561 PF03188.16 EEQ39564.1 - 0.038 14.1 1.8 0.093 12.9 1.1 2.0 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 B PF02216.16 EEQ39564.1 - 0.12 12.4 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 B domain DUF3624 PF12292.8 EEQ39564.1 - 4.4 7.8 6.1 0.44 11.0 0.3 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3624) AMP-binding PF00501.28 EEQ39566.1 - 6e-65 219.5 0.0 7.4e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ39566.1 - 1.5e-08 35.5 0.3 3.1e-08 34.5 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain YejG PF13989.6 EEQ39566.1 - 0.16 12.4 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein PGK PF00162.19 EEQ39567.1 - 6.9e-150 499.2 0.5 7.8e-150 499.0 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Fes1 PF08609.10 EEQ39568.1 - 6.4e-21 75.0 1.8 6.4e-21 75.0 1.8 3.1 3 2 1 4 4 4 1 Nucleotide exchange factor Fes1 DUF908 PF06012.12 EEQ39568.1 - 0.005 16.3 0.4 0.017 14.5 0.0 2.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4393 PF14337.6 EEQ39568.1 - 0.031 14.1 0.2 0.031 14.1 0.2 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4393) B2-adapt-app_C PF09066.10 EEQ39568.1 - 0.076 13.1 0.4 0.14 12.2 0.4 1.5 1 0 0 1 1 1 0 Beta2-adaptin appendage, C-terminal sub-domain ERCC4 PF02732.15 EEQ39569.1 - 1.1e-15 58.1 0.1 2.3e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 ERCC4 domain Sec8_exocyst PF04048.14 EEQ39570.1 - 1.1e-40 138.9 2.0 1.1e-40 138.9 2.0 3.1 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain DUF2451 PF10474.9 EEQ39570.1 - 2.8e-06 27.3 0.6 2.8e-06 27.3 0.6 2.7 2 0 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) TPR_7 PF13176.6 EEQ39570.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Ctr PF04145.15 EEQ39571.1 - 5.9e-24 85.4 1.0 5.9e-24 85.4 1.0 1.4 2 0 0 2 2 2 1 Ctr copper transporter family zf-Di19 PF05605.12 EEQ39572.1 - 0.1 12.9 1.5 0.28 11.5 0.0 2.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EEQ39572.1 - 0.13 12.7 2.0 1.6 9.3 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ39572.1 - 0.24 12.3 14.1 5.6 8.1 0.5 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EEQ39572.1 - 0.52 10.9 14.8 8.3 7.1 0.1 4.2 3 1 0 3 3 3 0 Zinc finger, C2H2 type HIM1 PF08732.10 EEQ39573.1 - 1.2e-10 41.2 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 HIM1 NAD_binding_10 PF13460.6 EEQ39573.1 - 1.2e-08 35.0 0.0 1.8e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EEQ39573.1 - 1e-07 31.7 0.0 1.8e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EEQ39573.1 - 0.0012 18.4 0.1 0.007 15.9 0.1 2.0 1 1 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EEQ39573.1 - 0.013 14.6 0.0 0.56 9.2 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain zf-C2H2_4 PF13894.6 EEQ39574.1 - 0.0066 17.2 14.2 0.4 11.7 0.3 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 EEQ39574.1 - 0.04 14.2 0.2 0.04 14.2 0.2 2.3 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 EEQ39574.1 - 0.14 12.7 16.7 4.2 8.0 0.2 4.5 3 1 0 3 3 3 0 Zinc finger, C2H2 type Zn_ribbon_recom PF13408.6 EEQ39574.1 - 0.6 10.7 4.2 4.4 7.9 1.9 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-BED PF02892.15 EEQ39574.1 - 4.3 7.4 7.3 1.5 8.9 2.8 2.6 1 1 1 2 2 2 0 BED zinc finger Ribosomal_L15e PF00827.17 EEQ39575.1 - 3.2e-89 297.7 11.1 3.9e-89 297.4 11.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.18 EEQ39576.1 - 1.2e-94 317.1 0.0 1.8e-94 316.5 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EEQ39576.1 - 8.8e-25 86.7 0.0 2.4e-24 85.3 0.0 1.8 1 0 0 1 1 1 1 MGS-like domain DnaJ PF00226.31 EEQ39577.1 - 4.4e-14 52.4 1.1 1.5e-13 50.6 1.1 2.0 1 0 0 1 1 1 1 DnaJ domain Man-6-P_recep PF02157.15 EEQ39577.1 - 0.016 14.3 0.0 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Acetyltransf_1 PF00583.25 EEQ39578.1 - 7.1e-16 58.5 0.0 8.7e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ39578.1 - 8.4e-10 38.9 0.0 1.5e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EEQ39578.1 - 1.4e-09 37.9 0.0 2.5e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ39578.1 - 0.00041 20.3 0.0 0.00064 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EEQ39578.1 - 0.004 17.3 0.1 0.007 16.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EEQ39578.1 - 0.064 12.9 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cyt-b5 PF00173.28 EEQ39579.1 - 8.1e-12 45.1 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4272 PF14094.6 EEQ39579.1 - 0.0098 15.2 0.0 0.021 14.0 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4272) RRM_9 PF18444.1 EEQ39580.1 - 5.3e-25 87.1 0.0 1.3e-24 85.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 EEQ39580.1 - 6.6e-13 48.1 2.6 9.9e-13 47.5 0.5 2.3 2 0 0 2 2 2 1 TAP C-terminal domain LRR_4 PF12799.7 EEQ39580.1 - 0.017 15.5 7.9 0.019 15.4 2.4 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEQ39580.1 - 7 6.5 10.5 0.3 10.9 2.1 2.8 2 1 1 3 3 3 0 Leucine rich repeat PIGA PF08288.12 EEQ39581.1 - 5.6e-40 135.8 0.4 1.4e-39 134.5 0.1 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EEQ39581.1 - 5e-28 98.2 0.1 8.1e-28 97.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EEQ39581.1 - 8.2e-28 97.1 0.0 1.5e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EEQ39581.1 - 2.7e-23 82.9 0.0 9.2e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEQ39581.1 - 8.4e-12 45.8 0.0 1.2e-11 45.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EEQ39581.1 - 5e-07 29.8 0.0 1e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EEQ39581.1 - 0.0028 18.0 0.0 0.0058 17.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TetR_C_29 PF17938.1 EEQ39581.1 - 0.049 13.7 0.0 0.17 12.0 0.0 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain CAP_GLY PF01302.25 EEQ39582.1 - 1.7e-22 79.2 0.4 3.4e-22 78.2 0.4 1.5 1 0 0 1 1 1 1 CAP-Gly domain DUF4407 PF14362.6 EEQ39582.1 - 0.088 12.1 30.3 0.14 11.5 0.5 4.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) GAS PF13851.6 EEQ39582.1 - 0.82 9.0 62.3 1.7 8.0 10.8 5.0 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF745 PF05335.13 EEQ39582.1 - 0.96 9.1 27.7 0.87 9.3 10.1 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF745) Retrotrans_gag PF03732.17 EEQ39582.1 - 1.5 9.1 14.7 1.8 8.9 0.3 4.5 2 1 2 4 4 4 0 Retrotransposon gag protein Fez1 PF06818.15 EEQ39582.1 - 3.1 8.2 60.8 0.091 13.2 10.6 4.3 2 2 2 4 4 4 0 Fez1 DASH_Dad1 PF08649.10 EEQ39582.1 - 4.7 7.5 22.2 0.76 10.0 0.2 5.8 5 0 0 5 5 5 0 DASH complex subunit Dad1 RPW8 PF05659.11 EEQ39582.1 - 9.7 5.9 28.7 0.82 9.4 0.6 5.6 4 1 1 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PRP9_N PF16958.5 EEQ39583.1 - 0.0055 16.7 2.4 0.012 15.6 2.4 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor PRP9 N-terminus AAA PF00004.29 EEQ39584.1 - 2e-43 147.9 0.0 4.1e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ39584.1 - 4.3e-09 36.0 0.1 9.8e-09 34.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EEQ39584.1 - 4e-07 30.6 0.0 0.00016 22.1 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EEQ39584.1 - 1.2e-06 28.6 0.1 2.3e-05 24.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ39584.1 - 3.4e-06 27.3 0.0 8.2e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EEQ39584.1 - 1.9e-05 24.5 0.1 3.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 EEQ39584.1 - 3e-05 23.8 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 EEQ39584.1 - 6.2e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EEQ39584.1 - 0.00065 20.0 0.2 0.029 14.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ39584.1 - 0.00099 19.7 0.1 0.0043 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EEQ39584.1 - 0.0028 16.9 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RNA_helicase PF00910.22 EEQ39584.1 - 0.0029 18.0 0.0 0.0069 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 EEQ39584.1 - 0.0052 16.2 0.1 0.012 15.1 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EEQ39584.1 - 0.0071 16.5 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EEQ39584.1 - 0.0087 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EEQ39584.1 - 0.012 15.7 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEQ39584.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EEQ39584.1 - 0.013 14.8 0.1 0.12 11.7 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 EEQ39584.1 - 0.027 14.0 0.0 0.066 12.7 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 EEQ39584.1 - 0.038 14.2 0.8 0.064 13.5 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 EEQ39584.1 - 0.059 12.8 0.2 0.11 11.9 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 EEQ39584.1 - 0.076 12.1 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EEQ39584.1 - 0.098 12.4 0.2 0.49 10.1 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 EEQ39584.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EEQ39584.1 - 0.11 12.8 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ39584.1 - 0.13 12.1 0.1 0.46 10.4 0.0 1.9 1 1 1 2 2 2 0 NACHT domain PriC PF07445.12 EEQ39584.1 - 0.18 11.7 3.8 0.31 11.0 3.8 1.3 1 0 0 1 1 1 0 Primosomal replication protein priC AAA_11 PF13086.6 EEQ39584.1 - 0.18 11.5 4.4 0.92 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EEQ39584.1 - 0.19 11.3 2.8 0.2 11.2 0.1 2.3 3 0 0 3 3 3 0 AAA domain Latarcin PF10279.9 EEQ39584.1 - 0.66 10.4 5.8 16 6.0 2.7 2.8 3 0 0 3 3 3 0 Latarcin precursor Hexapep PF00132.24 EEQ39585.1 - 4.9e-08 32.4 7.4 5.5e-05 22.7 2.3 3.3 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EEQ39585.1 - 2.8e-05 24.5 0.0 6.2e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EEQ39585.1 - 0.00064 19.4 3.6 0.033 13.9 1.6 2.5 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 EEQ39585.1 - 0.00078 19.1 0.0 0.0033 17.1 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyl transferase CTP_transf_3 PF02348.19 EEQ39585.1 - 0.0045 16.9 0.0 0.0085 16.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase DUF4954 PF16314.5 EEQ39585.1 - 0.015 13.5 3.2 0.11 10.6 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EEQ39585.1 - 0.049 12.6 1.7 0.076 11.9 1.7 1.2 1 0 0 1 1 1 0 L-fucokinase DUF4588 PF15251.6 EEQ39586.1 - 1.3e-71 241.4 7.9 1.5e-71 241.1 7.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4588) T2SSF PF00482.23 EEQ39586.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Mon1 PF03164.14 EEQ39587.1 - 2.7e-117 392.3 4.1 3.3e-117 392.0 4.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 RRF PF01765.19 EEQ39588.1 - 6.7e-39 133.4 0.7 6.7e-39 133.4 0.7 1.9 1 1 1 2 2 2 1 Ribosome recycling factor Ipi1_N PF12333.8 EEQ39589.1 - 5.3e-26 91.2 0.8 1.8e-25 89.5 0.8 1.9 1 0 0 1 1 1 1 Rix1 complex component involved in 60S ribosome maturation Adaptin_N PF01602.20 EEQ39589.1 - 0.0047 15.6 2.0 0.006 15.2 2.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Brr6_like_C_C PF10104.9 EEQ39590.1 - 1.8e-43 147.5 1.9 2.6e-43 147.0 1.9 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF4587 PF15248.6 EEQ39590.1 - 0.16 12.8 3.6 0.52 11.1 3.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4587) MFS_1 PF07690.16 EEQ39591.1 - 1.7e-22 79.9 43.1 1.7e-22 79.9 43.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M20 PF01546.28 EEQ39592.1 - 2.1e-23 83.1 0.0 3.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EEQ39592.1 - 9.1e-08 32.7 15.7 0.00055 20.7 0.4 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.14 EEQ39592.1 - 2e-07 30.9 0.0 4.3e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain ANAPC4_WD40 PF12894.7 EEQ39592.1 - 0.14 12.5 0.3 1.1 9.6 0.1 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SPX PF03105.19 EEQ39593.1 - 3e-45 155.8 17.3 5.3e-45 155.0 17.3 1.4 1 1 0 1 1 1 1 SPX domain CitMHS PF03600.16 EEQ39593.1 - 1.4e-16 60.6 15.0 1.4e-16 60.6 15.0 1.4 2 0 0 2 2 2 1 Citrate transporter Na_sulph_symp PF00939.19 EEQ39593.1 - 4e-15 55.8 20.6 6.2e-15 55.2 20.6 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region FAM176 PF14851.6 EEQ39593.1 - 1.7 8.3 11.5 1.3 8.7 2.5 3.6 3 1 0 3 3 3 0 FAM176 family Sporozoite_P67 PF05642.11 EEQ39593.1 - 2.3 6.2 4.9 3.4 5.7 4.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 EEQ39593.1 - 9.5 5.4 9.3 16 4.7 9.3 1.3 1 0 0 1 1 1 0 NOA36 protein PI3_PI4_kinase PF00454.27 EEQ39596.1 - 2.6e-42 145.4 0.0 4.9e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ApbA_C PF08546.11 EEQ39597.1 - 1.3e-25 90.0 0.0 2.4e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EEQ39597.1 - 1.9e-25 89.3 0.1 2.9e-25 88.7 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EEQ39597.1 - 0.0058 15.9 0.1 0.0093 15.3 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PglD_N PF17836.1 EEQ39597.1 - 0.0061 17.2 0.1 0.023 15.3 0.1 2.1 1 0 0 1 1 1 1 PglD N-terminal domain Pyr_redox PF00070.27 EEQ39597.1 - 0.0072 16.9 0.3 0.02 15.5 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EEQ39597.1 - 0.034 14.6 0.1 0.098 13.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 EEQ39597.1 - 0.037 13.6 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 EEQ39597.1 - 0.039 13.9 0.2 0.098 12.6 0.2 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GARS_N PF02844.15 EEQ39597.1 - 0.048 14.4 0.1 0.13 13.1 0.1 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain Phyto_Pns9_10 PF05878.11 EEQ39597.1 - 0.065 12.4 0.0 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 GFO_IDH_MocA PF01408.22 EEQ39597.1 - 0.12 13.2 0.2 0.28 12.0 0.1 1.7 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold FAD_binding_2 PF00890.24 EEQ39597.1 - 0.46 9.5 0.9 0.7 8.9 0.9 1.4 1 1 0 1 1 1 0 FAD binding domain Phos_pyr_kin PF08543.12 EEQ39598.1 - 2.2e-12 46.9 0.0 2.9e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EEQ39598.1 - 6.6e-06 25.6 0.1 2.2e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase bZIP_2 PF07716.15 EEQ39599.1 - 7.2e-07 29.2 8.5 7.2e-07 29.2 8.5 1.7 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 EEQ39599.1 - 2.6e-06 27.4 7.0 2.6e-06 27.4 7.0 1.7 2 0 0 2 2 2 1 bZIP transcription factor UPF0242 PF06785.11 EEQ39599.1 - 0.83 9.7 5.3 1.1 9.3 5.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DNA_pol_B PF00136.21 EEQ39600.1 - 1.1e-96 324.4 0.9 1.7e-96 323.8 0.9 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EEQ39600.1 - 1.6e-21 76.8 9.1 1.2e-15 57.5 1.6 2.8 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EEQ39600.1 - 3.3e-08 33.9 10.4 3.3e-08 33.9 10.4 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Pkinase PF00069.25 EEQ39601.1 - 9.6e-59 198.9 0.0 1.2e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39601.1 - 2.1e-36 125.6 0.0 2.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ39601.1 - 3.2e-07 30.0 0.0 5.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EEQ39601.1 - 0.00019 20.6 0.3 0.00037 19.6 0.3 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EEQ39601.1 - 0.0064 15.3 0.6 0.0088 14.9 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EEQ39601.1 - 0.019 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EEQ39601.1 - 0.21 10.5 0.1 0.32 9.9 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase P34-Arc PF04045.14 EEQ39602.1 - 5.1e-102 340.7 4.1 7.5e-102 340.1 4.1 1.2 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 EEQ39602.1 - 0.0066 16.1 1.7 0.22 11.1 1.7 2.4 1 1 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) CbiK PF06180.11 EEQ39602.1 - 0.052 12.9 0.5 0.081 12.2 0.5 1.3 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Ribosom_S12_S23 PF00164.25 EEQ39603.1 - 9.3e-33 112.2 1.5 1.3e-32 111.8 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 EEQ39603.1 - 0.074 13.8 0.0 0.15 12.8 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein S12 Mob_synth_C PF06463.13 EEQ39603.1 - 0.075 13.0 0.2 0.15 12.0 0.2 1.5 1 1 0 1 1 1 0 Molybdenum Cofactor Synthesis C PP-binding PF00550.25 EEQ39604.1 - 9.7e-12 45.1 0.2 1.2e-11 44.7 0.2 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EEQ39604.1 - 3.3e-06 27.2 0.4 4.7e-06 26.7 0.4 1.2 1 0 0 1 1 1 1 Acyl-carrier Met_synt_B12 PF02965.17 EEQ39604.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain Cullin PF00888.22 EEQ39605.1 - 1.3e-58 199.1 9.1 2.1e-58 198.4 9.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EEQ39605.1 - 1.2e-14 54.1 1.4 5.9e-14 51.8 0.0 2.9 3 0 0 3 3 3 1 Cullin protein neddylation domain PRP21_like_P PF12230.8 EEQ39605.1 - 0.11 12.3 0.2 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein COMPASS-Shg1 PF05205.12 EEQ39606.1 - 1.5e-27 96.3 4.2 1.9e-27 95.9 4.2 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 FCH PF00611.23 EEQ39607.1 - 2.5e-09 37.3 0.4 2.5e-09 37.3 0.4 2.0 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain ADK PF00406.22 EEQ39607.1 - 0.0045 17.1 0.6 0.0059 16.7 0.6 1.3 1 0 0 1 1 1 1 Adenylate kinase Ribosomal_L4 PF00573.22 EEQ39607.1 - 0.0077 15.9 0.8 0.013 15.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF4083 PF13314.6 EEQ39607.1 - 0.56 10.2 2.2 0.81 9.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) BLOC1_2 PF10046.9 EEQ39607.1 - 1.5 9.2 8.5 0.98 9.8 0.3 3.3 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LMBR1 PF04791.16 EEQ39607.1 - 2.9 6.7 4.9 3.6 6.4 4.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Chs7 PF12271.8 EEQ39608.1 - 2.2e-116 388.3 27.5 2.5e-116 388.1 27.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone TBPIP PF07106.13 EEQ39609.1 - 0.051 13.5 0.2 0.17 11.8 0.2 1.8 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain MetOD1 PF18546.1 EEQ39609.1 - 0.13 12.3 2.0 0.28 11.1 0.1 2.3 3 0 0 3 3 3 0 Metanogen output domain 1 SLIDE PF09111.10 EEQ39610.1 - 1.1e-39 135.0 1.0 1.1e-39 135.0 1.0 2.5 3 0 0 3 3 3 1 SLIDE HAND PF09110.11 EEQ39610.1 - 9.5e-35 119.7 4.4 9.5e-35 119.7 4.4 2.7 3 0 0 3 3 3 1 HAND DUF1086 PF06461.11 EEQ39610.1 - 0.0001 22.2 2.6 0.0012 18.8 0.1 2.9 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1086) Myb_DNA-binding PF00249.31 EEQ39610.1 - 0.00075 19.6 0.2 6.4 7.1 0.0 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain CutA1 PF03091.15 EEQ39610.1 - 0.1 12.5 0.9 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein CemA PF03040.14 EEQ39610.1 - 0.2 11.6 2.0 12 5.8 0.1 2.3 2 0 0 2 2 2 0 CemA family SNF2_N PF00176.23 EEQ39611.1 - 1.7e-76 257.2 0.2 2.9e-76 256.4 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EEQ39611.1 - 1.1e-10 41.8 0.1 3.1e-10 40.3 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ39611.1 - 6.1e-06 26.6 0.9 0.00017 21.9 0.1 2.8 3 1 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ39611.1 - 6.7e-06 26.0 0.0 1.6e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EEQ39611.1 - 5.9e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 EEQ39611.1 - 0.0024 17.1 0.4 0.014 14.6 0.1 2.2 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EEQ39611.1 - 0.022 14.0 0.4 0.046 12.9 0.4 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 EEQ39611.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain bZIP_1 PF00170.21 EEQ39613.1 - 4.4 7.5 6.2 1.2 9.3 2.2 2.0 2 0 0 2 2 2 0 bZIP transcription factor NST1 PF13945.6 EEQ39614.1 - 2.9e-05 24.3 15.5 2.9e-05 24.3 15.5 6.1 3 3 1 4 4 4 1 Salt tolerance down-regulator Ras PF00071.22 EEQ39615.1 - 1.8e-48 164.2 0.0 2.2e-48 164.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ39615.1 - 1.4e-22 80.1 0.0 1.9e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ39615.1 - 2.1e-06 27.3 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EEQ39615.1 - 0.07 12.6 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EEQ39615.1 - 0.091 12.5 0.0 4.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EEQ39615.1 - 0.21 11.7 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase adh_short_C2 PF13561.6 EEQ39616.1 - 7.2e-67 225.4 0.0 8.9e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EEQ39616.1 - 2.7e-41 141.2 0.0 3.2e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ39616.1 - 2.7e-10 40.4 0.0 4.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EEQ39616.1 - 0.00023 20.7 0.0 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EEQ39616.1 - 0.00093 19.5 0.0 0.0014 18.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain SLATT_3 PF18184.1 EEQ39616.1 - 0.0048 17.0 0.0 0.0075 16.4 0.0 1.3 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain 3 DFP PF04127.15 EEQ39616.1 - 0.0088 15.9 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein GDP_Man_Dehyd PF16363.5 EEQ39616.1 - 0.05 13.0 0.0 0.75 9.1 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase 3HCDH_N PF02737.18 EEQ39616.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EEQ39616.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 EEQ39616.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Vps5 PF09325.10 EEQ39617.1 - 6.7e-79 264.8 16.2 6.7e-79 264.8 16.2 2.0 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EEQ39617.1 - 3.5e-21 75.3 1.2 2e-20 72.8 0.0 2.4 2 0 0 2 2 2 1 PX domain Laminin_I PF06008.14 EEQ39617.1 - 0.0039 16.9 2.6 0.0039 16.9 2.6 2.1 3 0 0 3 3 3 1 Laminin Domain I DUF1664 PF07889.12 EEQ39617.1 - 0.0059 16.6 6.2 0.052 13.6 1.9 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) YabA PF06156.13 EEQ39617.1 - 0.017 15.7 4.7 0.017 15.7 4.7 2.9 3 0 0 3 3 3 0 Initiation control protein YabA DUF16 PF01519.16 EEQ39617.1 - 0.018 15.6 3.5 0.018 15.6 3.5 3.1 3 0 0 3 3 2 0 Protein of unknown function DUF16 Nucleoside_tran PF01733.18 EEQ39617.1 - 0.44 9.9 1.6 13 5.0 1.4 2.3 2 0 0 2 2 2 0 Nucleoside transporter FlaC_arch PF05377.11 EEQ39617.1 - 0.69 10.4 8.0 16 6.0 0.1 3.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 EEQ39617.1 - 0.95 8.7 6.7 1.7 7.9 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) OmpH PF03938.14 EEQ39617.1 - 0.97 9.8 11.3 0.24 11.8 4.1 2.9 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) BRE1 PF08647.11 EEQ39617.1 - 1.5 8.9 13.1 0.18 11.9 7.7 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.12 EEQ39617.1 - 1.6 8.8 10.6 3.5 7.6 1.4 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 EEQ39617.1 - 4 8.0 11.0 1.1 9.8 5.3 2.7 2 0 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 EEQ39617.1 - 6.5 7.2 14.6 3 8.3 5.5 3.7 3 1 1 4 4 4 0 Centromere protein H (CENP-H) DUF4446 PF14584.6 EEQ39617.1 - 9.4 6.2 9.8 1.9 8.5 3.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) ACT_7 PF13840.6 EEQ39618.1 - 2.2e-27 94.6 0.3 3e-13 49.3 0.0 2.5 2 0 0 2 2 2 2 ACT domain Castor1_N PF18700.1 EEQ39618.1 - 0.037 13.8 0.1 10 6.1 0.0 3.0 2 0 0 2 2 2 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain GYF PF02213.16 EEQ39619.1 - 4.5e-16 58.3 0.2 9.4e-16 57.2 0.2 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 EEQ39619.1 - 7.2e-06 25.7 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 GYF domain 2 UMP1 PF05348.11 EEQ39620.1 - 6.7e-43 145.7 0.1 7.9e-43 145.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 TPT PF03151.16 EEQ39621.1 - 8.7e-11 41.7 16.1 1.5e-10 40.9 16.1 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 EEQ39621.1 - 1e-10 41.4 6.9 1e-10 41.4 6.9 1.9 2 1 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 EEQ39621.1 - 4.1e-10 40.0 29.1 2.8e-07 30.8 7.2 3.1 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EEQ39621.1 - 9.7e-10 38.1 18.7 1.3e-09 37.7 18.7 1.2 1 0 0 1 1 1 1 UAA transporter family SLC35F PF06027.12 EEQ39621.1 - 1e-05 25.2 9.3 1e-05 25.2 9.3 1.6 2 0 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 EEQ39621.1 - 0.00027 20.3 20.1 0.00049 19.4 20.0 1.5 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 EEQ39621.1 - 0.01 14.8 17.9 0.0086 15.1 15.7 1.9 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like UNC-93 PF05978.16 EEQ39621.1 - 0.83 9.4 11.6 0.063 13.0 0.7 3.1 4 0 0 4 4 4 0 Ion channel regulatory protein UNC-93 Fig1 PF12351.8 EEQ39621.1 - 9.5 6.1 18.9 0.032 14.2 7.0 2.5 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Fibrillarin PF01269.17 EEQ39622.1 - 4.3e-105 349.9 0.0 5.2e-105 349.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EEQ39622.1 - 3.5e-06 26.9 0.0 6.2e-06 26.1 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 EEQ39622.1 - 0.015 15.4 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 EEQ39622.1 - 0.059 13.1 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EEQ39622.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Mucin PF01456.17 EEQ39623.1 - 8.8 6.3 40.3 18 5.3 40.3 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Usp PF00582.26 EEQ39625.1 - 9.9e-22 78.0 0.0 2.8e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family LAT PF15234.6 EEQ39625.1 - 1.4 8.6 9.8 0.11 12.2 4.3 1.8 2 0 0 2 2 2 0 Linker for activation of T-cells UBX PF00789.20 EEQ39626.1 - 2.5e-15 56.4 0.0 1e-14 54.5 0.0 2.1 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.6 EEQ39626.1 - 1.1e-06 28.3 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain RPA43_OB PF17875.1 EEQ39626.1 - 0.27 11.9 3.1 5.3 7.7 0.0 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I AAA_23 PF13476.6 EEQ39626.1 - 1.4 9.4 9.3 0.56 10.7 5.0 2.2 2 1 0 2 2 2 0 AAA domain PVL_ORF50 PF07768.11 EEQ39626.1 - 4.3 7.7 12.1 0.75 10.1 6.0 2.2 2 0 0 2 2 2 0 PVL ORF-50-like family DAO PF01266.24 EEQ39627.1 - 1.8e-54 185.7 0.0 2.5e-54 185.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EEQ39627.1 - 7.3e-42 142.2 0.0 2.3e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EEQ39627.1 - 6.6e-13 48.5 2.2 7.8e-12 45.0 2.2 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EEQ39627.1 - 9e-09 35.2 0.3 2e-06 27.4 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ39627.1 - 5.3e-05 22.6 0.4 0.00034 19.9 0.4 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ39627.1 - 8.7e-05 21.8 0.2 0.0074 15.4 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EEQ39627.1 - 0.0001 21.6 0.8 0.013 14.8 0.1 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 EEQ39627.1 - 0.0018 17.1 0.1 0.0028 16.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EEQ39627.1 - 0.0021 18.3 0.6 0.0071 16.6 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EEQ39627.1 - 0.008 15.5 0.0 0.022 14.0 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EEQ39627.1 - 0.02 14.2 0.0 0.056 12.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EEQ39627.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EEQ39627.1 - 0.079 12.8 0.4 0.27 11.1 0.4 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EEQ39627.1 - 0.11 12.9 0.1 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding GMC_oxred_N PF00732.19 EEQ39627.1 - 0.2 11.0 0.2 0.84 8.9 0.1 1.9 2 0 0 2 2 2 0 GMC oxidoreductase HAD_2 PF13419.6 EEQ39628.1 - 1.3e-16 61.2 0.0 1.8e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ39628.1 - 3.8e-10 40.4 0.0 0.0003 21.1 0.0 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ39628.1 - 0.023 15.1 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ39628.1 - 0.042 13.9 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_6 PF13344.6 EEQ39628.1 - 0.094 12.8 0.0 1.1 9.4 0.0 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase IFRD PF05004.13 EEQ39629.1 - 6e-15 55.1 3.1 4.7e-14 52.2 3.1 2.2 1 1 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Acetyltransf_1 PF00583.25 EEQ39630.1 - 4.4e-07 30.2 0.0 6e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EEQ39630.1 - 4.3e-06 26.6 0.0 6.8e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EEQ39630.1 - 0.0001 22.2 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ39630.1 - 0.0001 22.7 0.0 0.00015 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EEQ39630.1 - 0.028 14.6 0.0 0.044 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mcl1_mid PF12341.8 EEQ39631.1 - 9.8e-79 264.8 0.0 5.4e-78 262.3 0.0 2.1 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 EEQ39631.1 - 2.7e-08 34.0 0.0 0.00025 21.3 0.0 4.3 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EEQ39631.1 - 0.00013 21.4 0.1 0.00026 20.4 0.1 1.5 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus BBS2_Mid PF14783.6 EEQ39631.1 - 0.00033 20.7 0.8 11 6.1 0.0 4.6 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 EEQ39631.1 - 0.016 14.8 0.0 0.39 10.2 0.0 2.9 1 1 0 1 1 1 0 PQQ-like domain NBD94 PF16830.5 EEQ39631.1 - 0.081 13.3 0.1 0.25 11.8 0.1 1.8 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH PQQ_3 PF13570.6 EEQ39631.1 - 0.18 12.3 0.0 57 4.4 0.1 3.5 4 0 0 4 4 4 0 PQQ-like domain PQQ PF01011.21 EEQ39631.1 - 0.91 9.6 4.3 31 4.7 0.2 4.4 5 0 0 5 5 5 0 PQQ enzyme repeat K_trans PF02705.16 EEQ39632.1 - 1.2e-186 621.4 16.4 1.5e-186 621.0 16.4 1.1 1 0 0 1 1 1 1 K+ potassium transporter Rad51 PF08423.11 EEQ39633.1 - 2.1e-132 440.1 0.0 2.4e-132 439.9 0.0 1.0 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EEQ39633.1 - 2.2e-09 37.2 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EEQ39633.1 - 1.4e-07 31.3 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.6 EEQ39633.1 - 6.3e-07 29.9 0.3 1.5e-06 28.7 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain ATPase PF06745.13 EEQ39633.1 - 1.5e-05 24.5 0.6 4.2e-05 23.0 0.6 1.7 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EEQ39633.1 - 0.00021 20.7 0.1 0.0017 17.7 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 EEQ39633.1 - 0.067 13.5 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 EEQ39633.1 - 0.12 12.3 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 single-stranded DNA binding TraI N-terminal subdomain HhH-GPD PF00730.25 EEQ39633.1 - 0.15 12.5 0.0 0.62 10.6 0.0 1.9 1 1 1 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein PAXNEB PF05625.11 EEQ39633.1 - 0.17 11.0 2.9 0.63 9.1 0.9 2.2 1 1 1 2 2 2 0 PAXNEB protein Fungal_trans PF04082.18 EEQ39634.1 - 1.4e-14 53.8 2.6 2.6e-14 52.9 2.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ39634.1 - 5.1e-08 32.9 10.3 8.4e-08 32.2 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.21 EEQ39635.1 - 2e-31 108.5 0.0 2.8e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EEQ39635.1 - 1.8e-13 50.1 0.2 3e-13 49.4 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EEQ39635.1 - 2.6e-13 49.9 0.0 3.5e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin MCM PF00493.23 EEQ39636.1 - 1.2e-102 341.8 0.6 1.7e-102 341.2 0.6 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ39636.1 - 9.7e-39 132.1 0.1 2.4e-38 130.8 0.1 1.7 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EEQ39636.1 - 4.1e-31 107.4 0.7 8.7e-31 106.4 0.7 1.6 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EEQ39636.1 - 9.5e-26 90.1 1.8 1.2e-25 89.7 0.6 1.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ39636.1 - 2.6e-21 76.2 0.1 7.2e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ39636.1 - 2.9e-06 26.8 0.0 8.8e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EEQ39636.1 - 0.002 18.0 0.1 0.0083 16.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ39636.1 - 0.0021 17.8 0.1 0.0062 16.3 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Zn-ribbon_8 PF09723.10 EEQ39636.1 - 0.38 10.9 1.5 0.94 9.6 1.5 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2 PF00096.26 EEQ39637.1 - 0.00074 19.8 16.2 0.0034 17.7 1.6 4.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 EEQ39637.1 - 0.0067 16.8 1.2 0.0067 16.8 1.2 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EEQ39637.1 - 0.011 16.5 19.9 0.13 13.2 1.3 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EEQ39637.1 - 0.1 12.9 0.2 0.1 12.9 0.2 2.5 3 0 0 3 3 3 0 C2H2-type zinc ribbon TFIIA PF03153.13 EEQ39637.1 - 0.61 10.0 18.6 0.79 9.6 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GST_N_2 PF13409.6 EEQ39638.1 - 8.9e-25 86.8 0.0 2.4e-24 85.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EEQ39638.1 - 1.7e-14 53.6 0.0 3.8e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EEQ39638.1 - 3.1e-06 27.3 0.0 8.4e-06 25.9 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EEQ39638.1 - 1.4e-05 25.2 0.1 3.1e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EEQ39638.1 - 0.00017 22.0 0.0 0.085 13.3 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EEQ39638.1 - 0.012 16.2 0.0 0.022 15.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ras PF00071.22 EEQ39639.1 - 2.6e-24 85.7 0.0 3.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEQ39639.1 - 0.0035 16.6 0.1 0.0056 15.9 0.1 1.3 1 1 0 1 1 1 1 G-protein alpha subunit GTP_EFTU PF00009.27 EEQ39639.1 - 0.017 14.6 0.3 0.04 13.5 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 EEQ39639.1 - 0.051 13.8 0.1 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ39639.1 - 0.057 12.9 0.1 0.092 12.2 0.1 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family Inhibitor_I68 PF10468.9 EEQ39639.1 - 0.084 13.3 1.3 0.13 12.7 0.9 1.6 1 1 0 1 1 1 0 Carboxypeptidase inhibitor I68 PRC2_HTH_1 PF18118.1 EEQ39639.1 - 0.11 13.3 3.2 0.19 12.5 3.2 1.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain DUF4407 PF14362.6 EEQ39641.1 - 0.0086 15.5 2.8 0.0086 15.5 2.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 EEQ39641.1 - 0.0097 16.3 5.8 0.13 12.6 0.7 2.8 1 1 1 2 2 2 2 Syntaxin-like protein FAM76 PF16046.5 EEQ39641.1 - 0.081 12.3 5.1 0.11 11.9 5.1 1.2 1 0 0 1 1 1 0 FAM76 protein SOAR PF16533.5 EEQ39641.1 - 0.28 11.2 5.4 0.4 10.7 1.2 3.1 2 1 2 4 4 4 0 STIM1 Orai1-activating region WD40 PF00400.32 EEQ39642.1 - 3.2e-19 68.9 25.2 3.3e-05 24.6 0.3 6.7 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39642.1 - 2.6e-06 27.6 6.1 0.25 11.6 0.2 4.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PNP_UDP_1 PF01048.20 EEQ39643.1 - 1.5e-50 171.7 0.0 1.7e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily GATA PF00320.27 EEQ39644.1 - 0.14 11.8 1.2 0.37 10.4 0.2 2.1 2 0 0 2 2 2 0 GATA zinc finger DUF4637 PF15470.6 EEQ39644.1 - 0.56 9.9 7.7 2.9 7.6 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) tRNA-synt_1b PF00579.25 EEQ39645.1 - 6.6e-65 219.3 0.1 8.3e-65 219.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) MOZART1 PF12554.8 EEQ39645.1 - 0.035 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated NCD1 PF04904.13 EEQ39645.1 - 0.094 12.7 0.0 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Speriolin_C PF15059.6 EEQ39645.1 - 0.13 12.4 0.6 0.24 11.5 0.1 1.7 2 0 0 2 2 2 0 Speriolin C-terminus CK_II_beta PF01214.18 EEQ39646.1 - 1.4e-73 246.6 0.0 1.7e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 EEQ39646.1 - 0.076 13.1 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Hira PF07569.11 EEQ39647.1 - 6.6e-78 261.4 0.1 6.6e-78 261.4 0.1 2.4 3 0 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.32 EEQ39647.1 - 3.1e-13 50.0 7.6 0.13 13.2 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39647.1 - 1.7e-11 44.3 0.6 0.63 10.4 0.1 6.9 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EEQ39647.1 - 1.2e-05 25.0 0.9 2.7e-05 23.9 0.9 1.6 1 0 0 1 1 1 1 HIRA B motif WD40_like PF17005.5 EEQ39647.1 - 0.12 11.6 3.2 0.48 9.7 0.1 3.1 3 1 1 4 4 4 0 WD40-like domain PD40 PF07676.12 EEQ39647.1 - 0.2 11.6 5.2 1.9 8.5 0.4 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 EEQ39648.1 - 1.8e-29 101.4 14.2 6.5e-07 29.9 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39648.1 - 8.3e-10 38.8 2.0 0.036 14.4 0.3 4.5 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SNARE PF05739.19 EEQ39649.1 - 4.4e-11 42.6 2.0 9.9e-11 41.5 0.0 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.6 EEQ39649.1 - 1e-07 32.2 13.0 1e-07 32.2 13.0 2.5 2 0 0 2 2 2 1 Syntaxin-like protein MCPsignal PF00015.21 EEQ39649.1 - 0.0061 16.4 10.3 0.05 13.4 1.9 2.3 2 1 0 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Trimer_CC PF08954.11 EEQ39649.1 - 0.0078 15.8 0.8 0.018 14.6 0.2 2.0 1 1 0 1 1 1 1 Trimerisation motif Synaptobrevin PF00957.21 EEQ39649.1 - 0.065 13.0 2.1 3.3 7.6 0.1 2.9 3 0 0 3 3 3 0 Synaptobrevin Syntaxin PF00804.25 EEQ39649.1 - 0.11 12.2 18.7 0.15 11.7 18.7 1.2 1 0 0 1 1 1 0 Syntaxin DUF1664 PF07889.12 EEQ39649.1 - 0.14 12.2 13.4 0.1 12.7 4.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) GARP PF16731.5 EEQ39649.1 - 0.34 10.6 6.8 0.13 12.0 2.3 2.3 2 1 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF883 PF05957.13 EEQ39649.1 - 0.4 11.3 5.0 0.39 11.3 0.2 3.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF883) GSP_synth PF03738.14 EEQ39649.1 - 0.56 9.3 9.3 0.61 9.2 3.0 2.1 1 1 1 2 2 2 0 Glutathionylspermidine synthase preATP-grasp DUF4200 PF13863.6 EEQ39649.1 - 4.2 7.8 20.8 2.3 8.6 6.2 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF4200) GLE1 PF07817.13 EEQ39649.1 - 4.3 6.5 9.7 0.74 9.0 0.3 2.4 2 0 0 2 2 2 0 GLE1-like protein Pyr_redox_2 PF07992.14 EEQ39650.1 - 1.3e-52 178.9 0.1 1.5e-52 178.7 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ39650.1 - 3.3e-17 62.7 0.0 5.8e-15 55.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ39650.1 - 1.2e-16 61.1 0.1 5e-14 52.6 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EEQ39650.1 - 6.8e-05 22.1 1.6 1 8.3 0.3 3.6 2 2 0 4 4 4 2 Glucose inhibited division protein A K_oxygenase PF13434.6 EEQ39650.1 - 0.00069 18.8 0.1 4 6.5 0.0 3.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EEQ39650.1 - 0.0009 18.5 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.6 EEQ39650.1 - 0.0023 18.3 0.0 1.4 9.4 0.0 2.5 2 2 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EEQ39650.1 - 0.01 16.0 0.4 0.058 13.6 0.1 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EEQ39650.1 - 0.028 13.3 0.1 1.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Tryptophan halogenase Shikimate_DH PF01488.20 EEQ39650.1 - 0.077 13.1 0.3 6 6.9 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.24 EEQ39650.1 - 0.088 12.4 0.5 3.5 7.1 0.0 2.6 2 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EEQ39650.1 - 0.092 12.7 0.0 3.3 7.7 0.0 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding PX PF00787.24 EEQ39651.1 - 1.8e-13 50.5 0.0 2.2e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 PX domain NDUFA12 PF05071.16 EEQ39652.1 - 1e-08 35.9 9.2 6.8e-08 33.3 9.2 2.2 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Exonuc_VII_L PF02601.15 EEQ39652.1 - 0.18 11.3 3.3 0.19 11.3 3.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DDHD PF02862.17 EEQ39652.1 - 0.26 11.4 4.4 0.34 11.0 4.4 1.1 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EEQ39652.1 - 4.4 6.0 5.3 4.9 5.8 5.3 1.1 1 0 0 1 1 1 0 Presenilin CPL PF08144.11 EEQ39653.1 - 4e-38 131.0 8.8 1.4e-36 125.9 0.1 5.0 5 1 0 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 EEQ39653.1 - 2.4e-06 26.9 2.0 0.11 12.2 0.0 4.8 5 0 0 5 5 5 2 Pumilio-family RNA binding repeat DUF4253 PF14062.6 EEQ39653.1 - 0.16 12.2 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4253) CDC45 PF02724.14 EEQ39653.1 - 0.49 8.6 15.2 0.85 7.8 15.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.11 EEQ39653.1 - 0.59 10.1 27.4 0.22 11.5 23.6 2.2 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) BNIP2 PF12496.8 EEQ39653.1 - 1.5 9.3 13.3 4.4 7.7 13.3 1.8 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Drc1-Sld2 PF11719.8 EEQ39653.1 - 3.4 7.1 21.0 1.3 8.5 17.1 2.0 2 0 0 2 2 2 0 DNA replication and checkpoint protein BUD22 PF09073.10 EEQ39653.1 - 6.4 6.0 27.3 14 4.8 27.3 1.5 1 0 0 1 1 1 0 BUD22 Thioredoxin PF00085.20 EEQ39654.1 - 1.5e-27 95.6 0.0 2e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EEQ39654.1 - 6.5e-07 29.8 0.1 2e-06 28.2 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EEQ39654.1 - 3.2e-06 26.9 0.0 3.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EEQ39654.1 - 0.00017 21.0 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EEQ39654.1 - 0.00018 21.7 0.0 0.0022 18.3 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 EEQ39654.1 - 0.00024 20.8 0.1 0.00084 19.1 0.0 1.7 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.21 EEQ39654.1 - 0.00078 19.4 0.1 0.0027 17.6 0.1 1.8 1 1 1 2 2 2 1 AhpC/TSA family TraF PF13728.6 EEQ39654.1 - 0.0019 18.1 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DIM1 PF02966.16 EEQ39654.1 - 0.0025 17.6 0.0 0.0032 17.2 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_7 PF13899.6 EEQ39654.1 - 0.0048 17.1 0.1 0.0089 16.2 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like Phosducin PF02114.16 EEQ39654.1 - 0.013 14.4 0.0 0.014 14.3 0.0 1.0 1 0 0 1 1 1 0 Phosducin Glutaredoxin PF00462.24 EEQ39654.1 - 0.049 13.9 0.0 0.094 12.9 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin HyaE PF07449.11 EEQ39654.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE AAA PF00004.29 EEQ39655.1 - 1e-39 136.0 0.0 1.7e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EEQ39655.1 - 1.2e-11 44.2 0.4 2.4e-11 43.3 0.4 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EEQ39655.1 - 4.5e-10 39.3 0.0 8.8e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EEQ39655.1 - 1.3e-05 25.5 0.2 0.017 15.4 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 EEQ39655.1 - 6e-05 22.3 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 EEQ39655.1 - 7.9e-05 22.8 0.2 0.00029 21.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EEQ39655.1 - 0.00036 20.5 0.1 0.0018 18.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ39655.1 - 0.00091 19.7 0.2 0.0044 17.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EEQ39655.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EEQ39655.1 - 0.0034 17.6 0.3 0.0086 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.11 EEQ39655.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 EEQ39655.1 - 0.015 14.9 0.0 0.042 13.5 0.0 1.8 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain AAA_33 PF13671.6 EEQ39655.1 - 0.016 15.4 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EEQ39655.1 - 0.017 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 EEQ39655.1 - 0.022 14.8 0.1 0.086 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 EEQ39655.1 - 0.024 13.9 0.5 0.064 12.5 0.1 1.8 2 1 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 EEQ39655.1 - 0.025 14.0 0.1 0.48 9.7 0.1 2.3 1 1 0 2 2 2 0 KaiC AAA_18 PF13238.6 EEQ39655.1 - 0.03 14.9 0.0 0.07 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ39655.1 - 0.051 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EEQ39655.1 - 0.057 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EEQ39655.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EEQ39655.1 - 0.11 12.2 0.2 0.35 10.6 0.1 1.9 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 EEQ39655.1 - 0.14 11.6 0.5 0.48 9.9 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 EEQ39655.1 - 0.16 11.5 0.2 0.45 10.1 0.1 1.7 2 0 0 2 2 2 0 AAA domain Bax1-I PF01027.20 EEQ39656.1 - 2.5e-51 174.4 31.0 2.9e-51 174.2 31.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 EEQ39656.1 - 3.6 5.8 18.1 4.9 5.3 18.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) zf-RING_UBOX PF13445.6 EEQ39657.1 - 5.4e-09 35.9 2.3 7.3e-09 35.5 0.9 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEQ39657.1 - 1.9e-08 34.0 2.4 1.9e-08 34.0 2.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ39657.1 - 1.9e-08 34.0 4.1 3.2e-08 33.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ39657.1 - 2.4e-08 34.2 3.9 3.6e-08 33.6 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEQ39657.1 - 2.6e-07 30.4 7.7 9.9e-07 28.5 7.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ39657.1 - 9.7e-07 28.9 4.7 3.6e-06 27.0 4.9 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EEQ39657.1 - 1.2e-05 25.2 7.2 2.4e-05 24.2 7.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ39657.1 - 0.00026 20.8 7.2 0.0098 15.7 7.6 2.7 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EEQ39657.1 - 0.0072 16.3 3.4 0.043 13.9 3.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Tmpp129 PF10272.9 EEQ39657.1 - 0.0089 15.4 2.2 0.013 14.8 2.2 1.3 1 1 0 1 1 1 1 Putative transmembrane protein precursor zf-Di19 PF05605.12 EEQ39657.1 - 0.022 15.0 4.1 6.7 7.1 2.7 2.5 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding DUF4451 PF14616.6 EEQ39657.1 - 0.038 14.2 2.3 0.39 10.9 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) zf-rbx1 PF12678.7 EEQ39657.1 - 0.07 13.4 7.0 0.27 11.5 7.0 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger domain TerY_C PF15616.6 EEQ39657.1 - 0.093 12.8 6.4 10 6.3 6.4 2.3 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.6 EEQ39657.1 - 0.13 12.1 6.6 2.2 8.2 6.9 2.5 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 EEQ39657.1 - 0.14 12.3 5.8 0.33 11.1 5.8 1.7 1 1 0 1 1 1 0 FYVE zinc finger FANCL_C PF11793.8 EEQ39657.1 - 0.21 11.8 4.1 1.1 9.5 4.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EEQ39657.1 - 0.4 10.5 4.5 1.1 9.1 4.5 1.8 1 1 0 1 1 1 0 RING-like zinc finger PH PF00169.29 EEQ39658.1 - 1.4e-10 41.6 0.2 3.9e-10 40.2 0.2 1.8 1 0 0 1 1 1 1 PH domain PARP_reg PF02877.14 EEQ39658.1 - 0.026 14.6 0.9 0.12 12.5 0.9 2.1 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain TetR PF13972.6 EEQ39658.1 - 0.12 12.0 1.4 1.6 8.4 0.1 3.0 3 0 0 3 3 3 0 Bacterial transcriptional repressor WSC PF01822.19 EEQ39659.1 - 1.3e-12 47.7 12.0 1.3e-12 47.7 12.0 2.4 2 1 0 2 2 2 1 WSC domain DUF2207 PF09972.9 EEQ39659.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SKG6 PF08693.10 EEQ39659.1 - 0.011 15.2 1.1 0.04 13.3 1.1 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mid2 PF04478.12 EEQ39659.1 - 0.013 15.3 0.9 0.013 15.3 0.9 2.8 1 1 2 3 3 3 0 Mid2 like cell wall stress sensor Amnionless PF14828.6 EEQ39659.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.4 1 0 0 1 1 1 0 Amnionless DUF3042 PF11240.8 EEQ39659.1 - 0.052 13.6 0.5 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) DUF5305 PF17231.2 EEQ39659.1 - 0.073 12.5 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SOG2 PF10428.9 EEQ39659.1 - 0.39 9.9 22.8 0.76 8.9 22.8 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Podoplanin PF05808.11 EEQ39659.1 - 1.3 9.1 19.4 8.4 6.5 19.5 2.2 1 1 0 1 1 1 0 Podoplanin DUF4551 PF15087.6 EEQ39659.1 - 2.7 6.7 6.8 3.4 6.4 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Utp14 PF04615.13 EEQ39659.1 - 3.2 6.2 7.4 4.2 5.8 7.4 1.1 1 0 0 1 1 1 0 Utp14 protein Use1 PF09753.9 EEQ39660.1 - 8.4e-12 45.3 1.3 1e-11 45.1 1.3 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Glyco_hydro_67C PF07477.12 EEQ39660.1 - 0.11 12.0 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus Apolipoprotein PF01442.18 EEQ39660.1 - 0.13 12.1 2.5 0.17 11.7 1.8 1.5 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF3347 PF11827.8 EEQ39660.1 - 0.35 11.0 3.8 0.48 10.6 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) RRM_1 PF00076.22 EEQ39661.1 - 2.6e-22 78.4 4.4 2.1e-07 30.6 0.9 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ39661.1 - 7.3e-09 35.4 0.3 1 9.3 0.0 4.7 4 1 0 4 4 4 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EEQ39661.1 - 0.039 14.0 0.2 1.8 8.6 0.2 3.0 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 EEQ39661.1 - 0.04 13.7 0.0 0.62 9.9 0.0 2.7 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain TMCO5 PF14992.6 EEQ39662.1 - 0.0092 15.6 1.2 0.0092 15.6 1.2 1.8 2 0 0 2 2 2 1 TMCO5 family HrpB7 PF09486.10 EEQ39662.1 - 0.064 13.6 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) PKcGMP_CC PF16808.5 EEQ39662.1 - 1.9 8.4 5.9 26 4.8 1.5 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase PI3_PI4_kinase PF00454.27 EEQ39663.1 - 7.2e-55 186.5 0.9 1.5e-53 182.2 0.0 3.1 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EEQ39663.1 - 3.7e-26 92.1 0.6 3.7e-26 92.1 0.6 4.8 7 0 0 7 7 7 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EEQ39663.1 - 1.9e-12 46.8 0.0 4e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 FATC domain CCDC-167 PF15188.6 EEQ39663.1 - 0.0014 18.9 1.3 0.0062 16.8 1.3 2.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 4HB_MCP_1 PF12729.7 EEQ39663.1 - 0.67 9.5 8.5 0.1 12.1 4.2 1.8 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction GCV_T PF01571.21 EEQ39664.1 - 9.5e-87 290.6 0.0 1.1e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.12 EEQ39664.1 - 7.1e-05 23.0 0.0 0.0079 16.4 0.0 2.2 1 1 1 2 2 2 2 Sarcosine oxidase, gamma subunit family TbpB_A PF17484.2 EEQ39665.1 - 0.065 14.0 0.1 0.12 13.2 0.1 1.5 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B TPR_12 PF13424.6 EEQ39666.1 - 4.6e-09 36.5 0.1 0.065 13.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EEQ39666.1 - 9.9e-09 35.2 13.6 1.5e-08 34.6 4.3 3.6 3 1 0 3 3 3 1 Putative TPR-like repeat TPR_2 PF07719.17 EEQ39666.1 - 9.1e-08 31.7 1.9 0.043 13.9 0.1 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat SRP72 PF08492.12 EEQ39666.1 - 4.6e-07 30.2 5.9 4.6e-07 30.2 5.9 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 EEQ39666.1 - 7.4e-07 29.6 0.1 0.0084 16.6 0.0 4.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ39666.1 - 8.5e-06 26.2 0.0 1.2 10.1 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ39666.1 - 1.4e-05 25.2 7.1 0.88 9.8 0.3 5.5 4 1 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EEQ39666.1 - 8.1e-05 22.3 4.6 0.15 11.9 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ39666.1 - 8.8e-05 22.0 0.0 0.7 9.2 0.0 3.1 3 0 0 3 3 3 2 MalT-like TPR region TPR_3 PF07720.12 EEQ39666.1 - 0.0002 21.3 14.0 0.042 13.9 1.3 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EEQ39666.1 - 0.00035 20.3 0.1 1.2 9.1 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ39666.1 - 0.00041 20.8 0.8 0.28 11.9 0.1 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ39666.1 - 0.00086 18.9 8.1 0.051 13.3 0.7 4.1 4 0 0 4 4 4 1 TPR repeat TPR_8 PF13181.6 EEQ39666.1 - 0.0011 19.1 5.0 4.1 7.9 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SPO22 PF08631.10 EEQ39666.1 - 0.0016 18.0 3.5 0.65 9.4 0.1 3.2 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_16 PF13432.6 EEQ39666.1 - 0.0085 16.7 0.1 2 9.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat PPR PF01535.20 EEQ39666.1 - 0.018 15.3 0.0 5.3 7.5 0.0 4.2 5 0 0 5 5 3 0 PPR repeat TPR_7 PF13176.6 EEQ39666.1 - 0.043 13.8 0.4 54 4.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EEQ39666.1 - 2.9 8.0 6.5 37 4.5 0.1 3.7 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Acetyltransf_9 PF13527.7 EEQ39667.1 - 0.017 15.2 0.1 0.081 13.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ubiq_cyt_C_chap PF03981.12 EEQ39668.1 - 3.5e-40 137.3 0.2 8.4e-40 136.1 0.0 1.7 3 0 0 3 3 3 1 Ubiquinol-cytochrome C chaperone ADH_N PF08240.12 EEQ39669.1 - 4.3e-24 84.5 5.7 6.7e-24 83.9 5.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ39669.1 - 4.1e-20 72.1 0.0 7.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ39669.1 - 5.6e-07 30.7 0.0 9.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEQ39669.1 - 3.3e-05 23.3 0.2 9.5e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EEQ39669.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EEQ39669.1 - 0.052 13.7 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase WAC_Acf1_DNA_bd PF10537.9 EEQ39670.1 - 4.4e-38 129.9 1.6 1e-37 128.7 1.6 1.7 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 EEQ39670.1 - 7.2e-16 58.2 1.2 1.3e-15 57.5 1.2 1.4 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 EEQ39671.1 - 1.3e-06 28.8 0.4 1.3e-06 28.8 0.4 2.8 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 EEQ39671.1 - 1.9e-05 24.1 0.7 3.1e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 WSD PF15613.6 EEQ39672.1 - 1.4e-11 44.8 4.7 2.5e-11 43.9 0.0 2.5 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif RBDV_coat PF06593.11 EEQ39672.1 - 0.019 14.5 1.0 0.036 13.6 0.6 1.6 1 1 1 2 2 2 0 Raspberry bushy dwarf virus coat protein SKIP_SNW PF02731.15 EEQ39673.1 - 5.5e-50 169.2 2.9 7.6e-50 168.7 2.9 1.2 1 0 0 1 1 1 1 SKIP/SNW domain Herpes_UL14 PF03580.14 EEQ39673.1 - 0.0059 16.9 2.1 0.011 16.0 2.1 1.3 1 0 0 1 1 1 1 Herpesvirus UL14-like protein GDPD PF03009.17 EEQ39674.1 - 1.5e-21 77.3 0.1 2e-21 76.9 0.1 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF643 PF04867.12 EEQ39674.1 - 0.039 14.6 0.2 0.098 13.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF643) Peripla_BP_1 PF00532.21 EEQ39674.1 - 0.081 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family NUDIX PF00293.28 EEQ39675.1 - 5.3e-11 42.7 0.0 9.5e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EEQ39675.1 - 5.6e-06 25.9 0.4 1.2e-05 24.9 0.4 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain NUDIX-like PF09296.11 EEQ39675.1 - 5.3e-05 23.8 0.0 0.00017 22.2 0.0 1.9 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain DNA_ligase_ZBD PF03119.16 EEQ39675.1 - 0.0086 16.1 0.2 0.028 14.5 0.2 2.0 1 0 0 1 1 1 1 NAD-dependent DNA ligase C4 zinc finger domain NAD_binding_6 PF08030.12 EEQ39675.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DEAD PF00270.29 EEQ39676.1 - 3.7e-24 85.5 0.0 6.9e-23 81.3 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ39676.1 - 2.1e-18 66.7 0.0 6e-17 62.0 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39676.1 - 4.4e-08 33.3 0.1 2.4e-07 30.9 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EEQ39676.1 - 0.032 14.5 0.1 7.6 6.8 0.0 3.5 3 1 1 4 4 4 0 AAA domain DAP3 PF10236.9 EEQ39677.1 - 1.8e-63 214.6 0.2 2.7e-63 214.0 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_5 PF07728.14 EEQ39677.1 - 3.4e-05 23.9 0.0 0.0001 22.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EEQ39677.1 - 0.00081 19.3 0.2 0.002 18.1 0.2 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EEQ39677.1 - 0.0023 18.3 0.0 0.0054 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ39677.1 - 0.0048 17.2 0.0 0.032 14.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EEQ39677.1 - 0.0049 16.6 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Roc PF08477.13 EEQ39677.1 - 0.01 16.1 0.7 0.054 13.7 0.1 2.6 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EEQ39677.1 - 0.012 16.1 0.0 0.042 14.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MeaB PF03308.16 EEQ39677.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 EEQ39677.1 - 0.022 14.5 0.1 0.039 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ39677.1 - 0.025 14.6 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EEQ39677.1 - 0.026 14.0 0.0 0.081 12.4 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2703 PF10865.8 EEQ39677.1 - 0.047 13.9 0.1 0.098 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) NACHT PF05729.12 EEQ39677.1 - 0.064 13.2 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 EEQ39677.1 - 0.077 12.7 0.1 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EEQ39677.1 - 0.091 13.3 0.0 0.23 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ39677.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase UPF0113_N PF17833.1 EEQ39678.1 - 4.5e-31 107.3 0.1 7e-31 106.6 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EEQ39678.1 - 5.6e-24 84.2 0.0 1e-23 83.4 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain Pkinase PF00069.25 EEQ39681.1 - 2.4e-25 89.4 0.0 2.4e-25 89.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39681.1 - 8.6e-14 51.4 0.5 1.4e-13 50.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ39681.1 - 1.5e-09 37.1 6.3 9.4e-09 34.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EEQ39681.1 - 0.00029 20.9 4.7 0.0032 17.4 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Neur_chan_memb PF02932.16 EEQ39681.1 - 0.056 13.5 2.8 0.077 13.0 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EEQ39681.1 - 2.2 6.9 15.0 3 6.5 15.0 1.1 1 0 0 1 1 1 0 Presenilin Med26_C PF15693.5 EEQ39681.1 - 5.9 7.0 17.2 10 6.2 17.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal Hid1 PF12722.7 EEQ39681.1 - 9.6 4.2 14.2 13 3.8 14.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Peptidase_M1 PF01433.20 EEQ39683.1 - 1.4e-42 145.7 2.4 2.9e-42 144.7 2.4 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EEQ39683.1 - 2.9e-40 138.7 1.9 3.9e-40 138.3 0.1 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EEQ39683.1 - 6.5e-22 78.6 0.7 6.5e-22 78.6 0.7 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ABC_membrane PF00664.23 EEQ39684.1 - 5e-41 141.1 14.6 7.1e-41 140.7 14.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ39684.1 - 6e-35 120.7 0.1 1.5e-34 119.5 0.0 1.7 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 EEQ39684.1 - 3.2e-08 33.3 1.1 1.5e-05 24.6 1.1 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EEQ39684.1 - 0.00074 19.4 0.6 0.04 13.7 0.1 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EEQ39684.1 - 0.0014 18.3 0.3 0.0036 17.0 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ39684.1 - 0.0052 17.1 0.1 0.03 14.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.7 EEQ39684.1 - 0.023 13.6 0.0 0.053 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.6 EEQ39684.1 - 0.027 14.8 0.1 0.058 13.8 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 EEQ39684.1 - 0.066 13.7 1.8 0.2 12.1 1.8 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EEQ39684.1 - 0.073 13.5 0.0 0.56 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EEQ39684.1 - 0.087 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EEQ39684.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ39684.1 - 0.11 12.5 0.2 0.39 10.8 0.0 2.1 2 1 0 2 2 2 0 AAA domain TPP_enzyme_N PF02776.18 EEQ39685.1 - 1.6e-32 112.5 0.0 3.4e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EEQ39685.1 - 2.1e-28 98.7 0.0 9.2e-28 96.7 0.0 2.1 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EEQ39685.1 - 2.5e-13 50.1 0.0 6.4e-13 48.8 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.6 EEQ39685.1 - 0.14 12.3 0.5 22 5.3 0.1 2.6 2 0 0 2 2 2 0 OCC1 family HLH PF00010.26 EEQ39686.1 - 1.6e-13 50.4 5.2 1.6e-13 50.4 5.2 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain BcrAD_BadFG PF01869.20 EEQ39686.1 - 0.062 12.8 2.9 0.067 12.7 0.2 2.0 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family TFIIA PF03153.13 EEQ39686.1 - 0.19 11.7 20.0 0.25 11.3 20.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3450 PF11932.8 EEQ39686.1 - 5.6 6.2 19.8 0.38 10.0 4.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) LicD PF04991.13 EEQ39687.1 - 4.8e-33 115.2 13.7 6.4e-28 98.4 1.8 3.4 3 1 1 4 4 4 2 LicD family Xan_ur_permease PF00860.20 EEQ39688.1 - 1.7e-72 244.3 29.5 2.6e-72 243.7 29.5 1.2 1 0 0 1 1 1 1 Permease family SNARE PF05739.19 EEQ39689.1 - 8e-08 32.2 2.0 1.5e-07 31.3 2.0 1.5 1 0 0 1 1 1 1 SNARE domain Baculo_PEP_C PF04513.12 EEQ39689.1 - 0.0053 16.8 5.7 0.16 12.0 0.0 3.4 2 2 1 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2721 PF11026.8 EEQ39689.1 - 0.0068 16.3 0.8 1.9 8.4 0.6 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2721) PhoU PF01895.19 EEQ39689.1 - 0.027 14.9 3.2 0.05 14.1 0.7 2.5 3 0 0 3 3 3 0 PhoU domain P22_AR_C PF10548.9 EEQ39689.1 - 0.046 13.9 0.0 0.39 10.9 0.0 2.2 2 0 0 2 2 2 0 P22AR C-terminal domain DUF4407 PF14362.6 EEQ39689.1 - 0.17 11.2 1.7 0.47 9.8 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HEPN_AbiU2 PF18734.1 EEQ39689.1 - 0.44 10.0 3.9 0.18 11.3 0.3 2.2 3 1 0 3 3 3 0 AbiU2 Uso1_p115_C PF04871.13 EEQ39689.1 - 0.45 10.9 4.3 0.26 11.7 0.5 2.3 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4164 PF13747.6 EEQ39689.1 - 0.69 10.2 5.7 2.6 8.4 0.6 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4164) PMC2NT PF08066.12 EEQ39689.1 - 1 10.1 5.1 6.4 7.5 0.8 3.2 2 2 1 3 3 3 0 PMC2NT (NUC016) domain RecG_N PF17190.4 EEQ39689.1 - 8.2 7.2 7.0 8.7 7.2 0.1 3.1 3 1 1 4 4 4 0 RecG N-terminal helical domain Vps55 PF04133.14 EEQ39690.1 - 4.9e-40 136.1 6.9 5.7e-40 135.9 6.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Bax1-I PF01027.20 EEQ39690.1 - 6.2 6.6 13.7 22 4.8 13.7 1.7 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MPM1 PF17234.2 EEQ39691.1 - 8.1e-57 192.2 6.2 1.4e-56 191.4 6.2 1.4 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 tRNA-synt_1c PF00749.21 EEQ39692.1 - 2.2e-105 352.0 0.0 4.1e-105 351.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain GTF2I PF02946.14 EEQ39692.1 - 0.0089 16.1 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 GTF2I-like repeat SMC_N PF02463.19 EEQ39693.1 - 0.0021 17.5 16.0 0.004 16.6 16.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain FAM76 PF16046.5 EEQ39693.1 - 0.11 11.9 26.1 0.025 13.9 8.3 2.2 2 0 0 2 2 2 0 FAM76 protein PilJ PF13675.6 EEQ39693.1 - 0.16 12.0 10.5 0.038 14.0 1.3 3.2 3 1 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term HCMV_UL139 PF12507.8 EEQ39693.1 - 0.27 11.6 8.0 0.91 9.9 2.0 2.5 1 1 1 2 2 2 0 Human Cytomegalovirus UL139 protein Spc7 PF08317.11 EEQ39693.1 - 0.43 9.4 38.9 0.019 13.8 14.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein COX5A PF02284.16 EEQ39693.1 - 0.61 10.1 6.0 5.6 7.0 0.2 2.9 1 1 0 2 2 2 0 Cytochrome c oxidase subunit Va Baculo_PEP_C PF04513.12 EEQ39693.1 - 1.1 9.4 6.9 0.69 9.9 1.2 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus XhlA PF10779.9 EEQ39693.1 - 1.2 9.3 16.6 0.31 11.3 4.6 3.3 3 0 0 3 3 3 0 Haemolysin XhlA Laminin_II PF06009.12 EEQ39693.1 - 9.6 6.2 20.0 0.42 10.6 6.3 3.5 2 1 1 3 3 3 0 Laminin Domain II AAA_23 PF13476.6 EEQ39694.1 - 1.1e-16 62.0 36.1 1.3e-10 42.2 36.1 3.4 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EEQ39694.1 - 1.4e-13 51.3 1.0 1.9e-12 47.6 1.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EEQ39694.1 - 4.1e-12 46.0 8.1 1e-11 44.7 8.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EEQ39694.1 - 0.0001 22.0 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4618 PF15397.6 EEQ39694.1 - 0.00023 20.7 27.5 0.00023 20.7 27.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4618) Spc7 PF08317.11 EEQ39694.1 - 0.00085 18.3 19.5 0.00085 18.3 19.5 3.1 1 1 2 3 3 3 1 Spc7 kinetochore protein AAA_21 PF13304.6 EEQ39694.1 - 0.0013 18.7 0.6 0.0026 17.6 0.0 1.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EEQ39694.1 - 0.0016 18.9 0.0 0.0016 18.9 0.0 3.1 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_27 PF13514.6 EEQ39694.1 - 0.01 15.5 10.6 0.029 14.0 0.0 3.6 2 1 2 4 4 4 0 AAA domain Sugarporin_N PF11471.8 EEQ39694.1 - 0.017 15.0 0.6 0.069 13.1 0.6 2.0 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension ABC_tran PF00005.27 EEQ39694.1 - 0.021 15.4 0.0 0.021 15.4 0.0 3.3 2 1 0 2 2 1 0 ABC transporter HsbA PF12296.8 EEQ39694.1 - 0.039 14.4 2.1 0.33 11.4 0.2 2.9 3 0 0 3 3 3 0 Hydrophobic surface binding protein A AAA_33 PF13671.6 EEQ39694.1 - 0.046 13.9 2.2 0.068 13.3 0.2 2.6 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 EEQ39694.1 - 0.069 13.2 1.0 0.18 11.8 1.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF948 PF06103.11 EEQ39694.1 - 0.12 12.6 19.2 0.087 13.1 6.0 4.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.11 EEQ39694.1 - 0.16 12.5 33.1 0.14 12.8 2.6 4.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal GAS PF13851.6 EEQ39694.1 - 0.24 10.7 45.0 0.43 9.9 22.8 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MukB PF04310.12 EEQ39694.1 - 0.46 10.3 0.0 0.46 10.3 0.0 3.0 2 1 0 3 3 3 0 MukB N-terminal TPR_MLP1_2 PF07926.12 EEQ39694.1 - 0.67 10.0 46.6 5.1 7.2 23.5 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein RasGAP_C PF03836.15 EEQ39694.1 - 0.68 10.1 33.7 0.58 10.3 1.8 4.3 2 1 0 3 3 3 0 RasGAP C-terminus DUF1664 PF07889.12 EEQ39694.1 - 0.77 9.8 29.4 0.11 12.5 9.2 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 EEQ39694.1 - 0.92 9.8 10.3 1.7 9.0 1.0 3.9 3 1 1 4 4 3 0 Proteins of 100 residues with WXG DUF3584 PF12128.8 EEQ39694.1 - 1.1 6.7 39.0 2.7 5.4 39.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 EEQ39694.1 - 1.2 9.2 51.5 3.1 7.8 26.3 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 EEQ39694.1 - 1.2 7.6 34.2 0.97 8.0 17.4 2.3 1 1 1 2 2 2 0 Flagellar Assembly Protein A AAA_13 PF13166.6 EEQ39694.1 - 1.3 7.6 37.5 1.5 7.3 0.2 2.5 2 1 0 2 2 2 0 AAA domain Sec34 PF04136.15 EEQ39694.1 - 1.4 8.8 28.6 1.9 8.4 1.3 4.2 1 1 1 4 4 4 0 Sec34-like family DUF812 PF05667.11 EEQ39694.1 - 1.4 7.7 46.4 0.061 12.2 14.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Atg14 PF10186.9 EEQ39694.1 - 1.4 7.9 39.2 1.1 8.3 15.1 2.5 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 MIP-T3_C PF17749.1 EEQ39694.1 - 1.7 8.6 28.2 0.27 11.2 18.0 2.8 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Noelin-1 PF12308.8 EEQ39694.1 - 2.6 8.1 15.3 0.31 11.0 2.5 3.7 1 1 2 3 3 3 0 Neurogenesis glycoprotein NPV_P10 PF05531.12 EEQ39694.1 - 3.4 8.2 16.3 37 4.9 3.8 4.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ERM PF00769.19 EEQ39694.1 - 3.7 7.3 49.1 3.3 7.5 35.1 2.8 2 1 0 2 2 2 0 Ezrin/radixin/moesin family TolA_bind_tri PF16331.5 EEQ39694.1 - 3.9 7.6 14.6 0.11 12.6 2.4 3.5 3 1 0 3 3 3 0 TolA binding protein trimerisation DUF745 PF05335.13 EEQ39694.1 - 5.2 6.8 27.6 1.9 8.2 17.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF745) Lectin_N PF03954.14 EEQ39694.1 - 5.7 6.7 14.8 1.8 8.3 4.5 3.1 2 2 1 3 3 3 0 Hepatic lectin, N-terminal domain ADIP PF11559.8 EEQ39694.1 - 6.1 6.9 39.3 1 9.5 14.4 3.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding zf-C4H2 PF10146.9 EEQ39694.1 - 7.2 6.9 37.1 3.3 8.0 25.6 2.7 1 1 0 2 2 2 0 Zinc finger-containing protein Laminin_II PF06009.12 EEQ39694.1 - 7.8 6.5 28.8 12 5.9 12.5 4.1 2 1 3 5 5 5 0 Laminin Domain II Tim17 PF02466.19 EEQ39695.1 - 0.00051 20.4 1.0 0.00076 19.8 1.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family eRF1_1 PF03463.15 EEQ39696.1 - 5.5e-37 126.7 0.3 1e-36 125.8 0.3 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EEQ39696.1 - 2.2e-24 86.3 0.1 3.8e-24 85.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EEQ39696.1 - 2.3e-24 86.1 0.1 1.7e-23 83.2 0.0 2.5 3 0 0 3 3 3 1 eRF1 domain 3 tRNA_bind PF01588.20 EEQ39697.1 - 2.2e-26 91.8 0.0 4.9e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GAGA_bind PF06217.12 EEQ39697.1 - 0.039 14.2 2.2 0.055 13.7 2.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family GFO_IDH_MocA PF01408.22 EEQ39698.1 - 2.4e-21 76.8 0.0 3.8e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EEQ39698.1 - 6.6e-06 26.8 0.0 1.2e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EEQ39698.1 - 0.011 16.2 0.1 0.033 14.6 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Antimicrobial22 PF16047.5 EEQ39698.1 - 0.17 11.8 1.1 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Frog antimicrobial peptide F420_oxidored PF03807.17 EEQ39698.1 - 0.2 12.2 0.2 0.56 10.8 0.2 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PhyH PF05721.13 EEQ39699.1 - 1.1e-13 51.9 0.0 1.9e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AraC_binding PF02311.19 EEQ39699.1 - 0.095 12.6 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_2 PF07883.11 EEQ39699.1 - 0.11 12.2 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 Cupin domain PAS PF00989.25 EEQ39700.1 - 4e-06 26.8 0.0 7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold Sugar_tr PF00083.24 EEQ39701.1 - 1.4e-97 327.4 15.6 2.7e-97 326.5 15.6 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ39701.1 - 7.7e-34 117.2 47.5 6.5e-30 104.2 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ39701.1 - 1.9e-07 30.7 8.7 1.9e-07 30.7 8.7 2.0 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EEQ39701.1 - 0.00029 19.4 5.6 0.00029 19.4 5.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) FA_desaturase PF00487.24 EEQ39701.1 - 1.4 8.7 8.9 0.21 11.4 1.4 2.4 2 0 0 2 2 2 0 Fatty acid desaturase Ribosomal_L27A PF00828.19 EEQ39702.1 - 3.2e-22 79.6 0.1 4.3e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HD_3 PF13023.6 EEQ39703.1 - 4.4e-39 134.1 0.2 5.6e-39 133.7 0.2 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EEQ39703.1 - 6.3e-11 42.4 0.1 8.4e-11 41.9 0.1 1.3 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EEQ39703.1 - 1.5e-06 28.4 0.2 3e-06 27.5 0.2 1.5 1 0 0 1 1 1 1 HD domain Evr1_Alr PF04777.13 EEQ39704.1 - 2.9e-31 107.9 1.5 3.8e-31 107.5 1.5 1.1 1 0 0 1 1 1 1 Erv1 / Alr family Thioredoxin_2 PF13098.6 EEQ39705.1 - 0.0013 19.2 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EEQ39705.1 - 0.0064 16.8 0.0 0.057 13.7 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin PF00085.20 EEQ39705.1 - 0.028 14.4 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin BH3 PF15285.6 EEQ39705.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting Mito_carr PF00153.27 EEQ39706.1 - 7e-53 176.5 2.5 2.5e-17 62.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GATA PF00320.27 EEQ39707.1 - 4e-30 103.1 15.3 2e-15 56.1 5.8 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EEQ39707.1 - 2.8e-07 29.9 3.3 0.0014 18.1 0.1 2.6 2 0 0 2 2 2 2 TFIIB zinc-binding zf-RRN7 PF11781.8 EEQ39707.1 - 0.0002 20.9 3.2 0.18 11.5 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 ArfGap PF01412.18 EEQ39707.1 - 0.00063 19.8 12.2 0.035 14.2 0.6 3.1 2 1 1 3 3 3 2 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 EEQ39707.1 - 0.0032 17.3 0.9 0.0032 17.3 0.9 3.0 4 0 0 4 4 3 1 Putative transposase DNA-binding domain TDP43_N PF18694.1 EEQ39707.1 - 0.0062 16.4 0.1 0.42 10.5 0.1 2.4 2 0 0 2 2 2 1 Transactive response DNA-binding protein N-terminal domain Auto_anti-p27 PF06677.12 EEQ39707.1 - 0.0074 16.4 6.4 0.28 11.4 0.5 2.7 3 0 0 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.10 EEQ39707.1 - 0.0077 16.3 3.9 1.2 9.3 0.2 2.8 3 0 0 3 3 3 2 Zinc ribbon domain PP2C PF00481.21 EEQ39707.1 - 0.03 14.0 1.4 0.052 13.2 1.4 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C eIF-5_eIF-2B PF01873.17 EEQ39707.1 - 1.5 8.7 8.2 4.6 7.1 0.5 2.8 3 0 0 3 3 3 0 Domain found in IF2B/IF5 DZR PF12773.7 EEQ39707.1 - 1.6 8.8 14.7 5.6 7.1 2.1 3.5 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EEQ39707.1 - 3.7 7.9 7.3 0.48 10.7 0.4 2.8 2 1 1 3 3 3 0 zinc-ribbon Pkinase PF00069.25 EEQ39708.1 - 1.3e-44 152.6 0.0 4.3e-44 150.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39708.1 - 2.9e-27 95.6 0.0 5.8e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase COX4 PF02936.14 EEQ39710.1 - 1.4e-32 112.6 0.2 2.5e-32 111.8 0.1 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase subunit IV UvrA_DNA-bind PF17755.1 EEQ39710.1 - 0.07 13.5 0.5 1.2 9.5 0.1 2.6 2 1 1 3 3 3 0 UvrA DNA-binding domain Sec3_C PF09763.9 EEQ39711.1 - 5.2e-96 322.6 27.6 6.9e-96 322.2 27.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EEQ39711.1 - 4.2e-15 55.6 0.1 9e-15 54.6 0.1 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec66 PF09802.9 EEQ39712.1 - 4.6e-64 215.3 0.3 5.6e-64 215.0 0.3 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SieB PF14163.6 EEQ39712.1 - 0.0064 16.0 1.5 0.043 13.3 0.1 2.3 2 0 0 2 2 2 1 Super-infection exclusion protein B HLH PF00010.26 EEQ39712.1 - 0.19 11.7 1.2 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain HTH_12 PF08461.10 EEQ39712.1 - 0.36 10.8 2.3 1.3 9.0 0.1 2.5 3 0 0 3 3 3 0 Ribonuclease R winged-helix domain Arf PF00025.21 EEQ39714.1 - 1.3e-36 125.7 0.0 7.6e-35 119.9 0.0 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EEQ39714.1 - 2.6e-11 43.3 0.1 5.8e-05 22.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EEQ39714.1 - 2.5e-10 40.6 0.1 9.6e-08 32.3 0.0 2.4 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EEQ39714.1 - 3e-09 36.7 0.0 2.2e-08 33.9 0.0 2.0 1 1 1 2 2 2 1 Ras family SRPRB PF09439.10 EEQ39714.1 - 3.8e-08 33.0 0.0 6.4e-05 22.5 0.0 2.2 1 1 1 2 2 2 2 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EEQ39714.1 - 1.8e-05 24.4 0.0 3e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EEQ39714.1 - 2.2e-05 23.9 0.0 5.9e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ39714.1 - 0.00011 22.3 0.0 0.00023 21.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EEQ39714.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EEQ39714.1 - 0.063 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 EEQ39714.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.18 EEQ39714.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Septin BAR_2 PF10455.9 EEQ39715.1 - 1.2e-80 270.8 8.2 1.6e-80 270.3 8.2 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EEQ39715.1 - 9.2e-05 22.2 8.2 0.00054 19.7 1.1 2.8 2 2 0 2 2 2 2 BAR domain Fib_alpha PF08702.10 EEQ39715.1 - 0.012 15.8 2.6 0.012 15.8 2.6 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EEQ39715.1 - 1.5 8.9 5.5 1.5 8.9 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) PRP38 PF03371.15 EEQ39716.1 - 5.8e-52 176.1 0.9 6.9e-52 175.8 0.9 1.0 1 0 0 1 1 1 1 PRP38 family DUF2286 PF10051.9 EEQ39716.1 - 0.038 13.7 0.1 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2286) CSG2 PF16965.5 EEQ39717.1 - 8.5e-08 31.6 21.9 8.8e-06 24.9 20.9 3.0 1 1 0 1 1 1 1 Ceramide synthase regulator EamA PF00892.20 EEQ39717.1 - 1.5e-05 25.2 45.1 1.7e-05 25.0 7.4 3.3 3 2 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EEQ39717.1 - 0.3 10.2 11.6 1.2 8.2 11.6 1.9 1 1 0 1 1 1 0 Nucleotide-sugar transporter TMEM234 PF10639.9 EEQ39717.1 - 1.2 9.2 11.8 3.9 7.5 3.0 2.7 2 0 0 2 2 2 0 Putative transmembrane family 234 RSV_NS2 PF03113.14 EEQ39718.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 WD40_like PF17005.5 EEQ39718.1 - 0.12 11.6 1.7 21 4.3 0.1 3.3 2 2 1 3 3 3 0 WD40-like domain BBP1_C PF15272.6 EEQ39719.1 - 0.0004 20.3 2.4 0.00045 20.1 2.4 1.1 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Fib_alpha PF08702.10 EEQ39719.1 - 0.17 12.1 6.2 0.24 11.6 6.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family cwf21 PF08312.12 EEQ39719.1 - 0.61 10.3 8.3 0.19 11.9 3.2 2.2 2 0 0 2 2 2 0 cwf21 domain ACCA PF03255.14 EEQ39719.1 - 4 7.3 5.1 1.2 9.0 2.2 1.5 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Kinesin PF00225.23 EEQ39720.1 - 3.3e-106 355.0 3.4 3.7e-106 354.8 3.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EEQ39720.1 - 6.1e-24 84.7 0.1 1.1e-23 83.8 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding 2-Hacid_dh_C PF02826.19 EEQ39721.1 - 2.7e-54 183.2 0.0 5.1e-54 182.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ39721.1 - 2.5e-37 127.5 0.1 3.3e-37 127.1 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EEQ39721.1 - 1.5e-05 25.2 0.3 4.9e-05 23.5 0.3 1.9 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EEQ39721.1 - 3.1e-05 24.1 0.2 6e-05 23.2 0.2 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 EEQ39721.1 - 4.8e-05 23.0 0.0 0.00016 21.3 0.0 1.9 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 EEQ39721.1 - 0.00062 19.4 0.1 0.0077 15.8 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 EEQ39721.1 - 0.014 15.9 0.0 0.051 14.1 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain UDPGT PF00201.18 EEQ39721.1 - 0.071 11.9 0.1 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase DpaA_N PF16924.5 EEQ39721.1 - 0.12 12.5 0.1 3.9 7.6 0.0 2.8 2 1 0 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain RPN2_C PF18004.1 EEQ39722.1 - 4.5e-49 166.4 19.6 1.5e-48 164.7 16.0 2.5 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EEQ39722.1 - 2.6e-40 134.8 21.3 4.6e-06 26.8 0.1 8.6 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EEQ39722.1 - 3.8e-16 59.2 0.3 4e-14 52.8 0.1 3.4 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 EEQ39722.1 - 4.8e-05 23.3 0.1 5 7.7 0.0 4.5 5 0 0 5 5 5 2 HEAT repeat DUF4042 PF13251.6 EEQ39722.1 - 0.0016 18.2 0.0 0.024 14.3 0.0 2.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 EEQ39722.1 - 0.017 15.7 0.3 16 6.1 0.0 3.9 3 1 1 4 4 4 0 HEAT-like repeat Telomere_reg-2 PF10193.9 EEQ39722.1 - 0.48 10.9 2.5 22 5.5 0.1 3.4 3 1 0 3 3 3 0 Telomere length regulation protein DAGK_cat PF00781.24 EEQ39723.1 - 8.4e-25 86.8 0.0 1.6e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Arrestin_C PF02752.22 EEQ39724.1 - 4.6e-11 43.3 0.0 8.7e-10 39.2 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Amino_oxidase PF01593.24 EEQ39725.1 - 1.5e-16 60.8 0.0 1.8e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EEQ39725.1 - 2.9e-12 46.6 0.0 6.7e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EEQ39725.1 - 2.1e-05 23.9 0.0 5.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EEQ39725.1 - 0.00021 21.0 0.0 0.0021 17.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEQ39725.1 - 0.00098 19.6 0.0 0.021 15.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EEQ39725.1 - 0.028 13.0 0.0 0.068 11.7 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF2969 PF11184.8 EEQ39725.1 - 0.028 14.8 0.7 0.076 13.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2969) NAD_binding_9 PF13454.6 EEQ39725.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding RRM_5 PF13893.6 EEQ39726.1 - 8.3e-10 38.3 0.0 8.9e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EEQ39726.1 - 1.2e-05 25.1 0.0 2.3e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ39726.1 - 0.026 14.4 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif PCRF PF03462.18 EEQ39727.1 - 5e-51 173.3 1.1 1.4e-50 171.9 0.0 1.9 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 EEQ39727.1 - 1.3e-36 125.0 2.8 1.3e-36 125.0 2.8 2.2 2 0 0 2 2 2 1 RF-1 domain MIR PF02815.19 EEQ39727.1 - 0.071 13.0 0.9 0.42 10.4 0.0 2.4 2 1 1 3 3 3 0 MIR domain FA_FANCE PF11510.8 EEQ39727.1 - 0.11 11.8 0.2 0.2 11.0 0.2 1.4 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE DUF952 PF06108.12 EEQ39727.1 - 0.16 12.0 0.2 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF952) DUF5478 PF17572.2 EEQ39727.1 - 0.18 11.9 0.1 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5478) Bacillus_HBL PF05791.11 EEQ39728.1 - 0.0071 16.2 5.7 0.0088 15.9 5.7 1.1 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 EEQ39728.1 - 0.0089 14.9 5.6 0.011 14.7 5.6 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein UPF0242 PF06785.11 EEQ39728.1 - 0.011 15.8 5.7 0.015 15.4 5.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4795 PF16043.5 EEQ39728.1 - 0.024 14.2 3.4 0.028 14.0 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TBCA PF02970.16 EEQ39728.1 - 0.061 13.7 3.8 0.086 13.2 3.8 1.4 1 1 0 1 1 1 0 Tubulin binding cofactor A DSHCT PF08148.12 EEQ39728.1 - 0.061 13.0 0.2 0.071 12.8 0.2 1.1 1 0 0 1 1 1 0 DSHCT (NUC185) domain Seryl_tRNA_N PF02403.22 EEQ39728.1 - 0.066 13.4 5.5 0.086 13.1 5.5 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2682 PF10909.8 EEQ39728.1 - 0.15 12.6 2.8 0.19 12.3 2.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2682) Cluap1 PF10234.9 EEQ39728.1 - 0.15 11.4 5.5 0.17 11.2 5.5 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_BLRF2 PF05812.12 EEQ39728.1 - 0.26 11.4 4.4 0.37 10.9 4.3 1.3 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein SlyX PF04102.12 EEQ39728.1 - 1.3 9.7 8.8 5.6 7.7 1.8 2.1 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 EEQ39728.1 - 2 8.2 9.8 0.17 11.7 1.5 2.1 1 1 1 2 2 2 0 Septum formation initiator Methyltransf_23 PF13489.6 EEQ39729.1 - 1.9e-21 76.6 0.0 3.5e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ39729.1 - 1.1e-14 54.9 0.0 3.8e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ39729.1 - 9e-13 48.8 0.0 3.1e-12 47.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ39729.1 - 1.1e-12 48.0 0.0 2.1e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ39729.1 - 2e-11 43.7 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EEQ39729.1 - 2.3e-11 44.2 0.0 5.5e-11 43.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EEQ39729.1 - 0.058 12.6 0.0 0.12 11.5 0.0 1.5 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DUF2341 PF10102.9 EEQ39729.1 - 0.059 14.0 0.6 0.12 12.9 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) RPN6_N PF18055.1 EEQ39730.1 - 1.2e-34 119.2 3.8 3.6e-34 117.6 1.4 2.6 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EEQ39730.1 - 5.4e-17 62.2 2.3 4.5e-16 59.3 0.2 2.7 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EEQ39730.1 - 2.4e-11 43.2 0.4 4.9e-11 42.1 0.4 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_MalT PF17874.1 EEQ39730.1 - 0.016 14.6 0.3 0.025 14.0 0.3 1.2 1 0 0 1 1 1 0 MalT-like TPR region DDRGK PF09756.9 EEQ39730.1 - 0.018 14.6 0.2 0.043 13.4 0.2 1.6 1 0 0 1 1 1 0 DDRGK domain Nup84_Nup100 PF04121.13 EEQ39731.1 - 2.7e-144 482.0 11.0 3.2e-144 481.8 11.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Sec16_C PF12931.7 EEQ39731.1 - 0.021 14.5 0.2 0.056 13.1 0.2 1.8 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 Vps39_2 PF10367.9 EEQ39731.1 - 0.06 13.8 0.6 0.88 10.0 0.0 2.8 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 PX PF00787.24 EEQ39732.1 - 2.8e-19 69.1 0.4 7.4e-19 67.8 0.1 1.9 2 0 0 2 2 2 1 PX domain DUF349 PF03993.12 EEQ39732.1 - 0.069 13.5 2.3 2.4 8.5 0.0 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Peptidase_C10 PF01640.17 EEQ39732.1 - 0.091 13.1 0.1 0.091 13.1 0.1 2.3 2 1 1 3 3 3 0 Peptidase C10 family FERM_M PF00373.18 EEQ39732.1 - 0.36 11.2 6.7 0.18 12.2 3.3 2.1 2 0 0 2 2 2 0 FERM central domain Adenyl_cycl_N PF12633.7 EEQ39732.1 - 0.4 10.6 4.1 0.33 10.8 1.3 2.1 2 0 0 2 2 2 0 Adenylate cyclase NT domain Lin-8 PF03353.15 EEQ39732.1 - 2.2 7.7 17.8 0.058 13.0 6.1 2.4 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF3445 PF11927.8 EEQ39733.1 - 7.7e-71 238.3 0.2 9.3e-71 238.0 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DUF3139 PF11337.8 EEQ39733.1 - 0.055 14.1 0.2 0.14 12.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) SpoU_methylase PF00588.19 EEQ39734.1 - 1.2e-24 87.1 0.0 2.7e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family RNase_PH PF01138.21 EEQ39735.1 - 2.7e-06 27.9 0.1 7e-06 26.6 0.1 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEQ39735.1 - 0.0019 18.2 0.0 0.0044 17.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 Nup35_RRM PF05172.13 EEQ39736.1 - 2e-25 88.7 0.1 4.7e-25 87.5 0.0 1.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EEQ39736.1 - 0.00032 20.6 0.1 0.0015 18.5 0.1 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Importin_rep_2 PF18786.1 EEQ39736.1 - 0.13 12.1 0.1 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 Importin 13 repeat DUF485 PF04341.12 EEQ39738.1 - 0.015 15.2 0.1 4.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Tudor_3 PF18115.1 EEQ39738.1 - 0.033 14.0 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 DNA repair protein Crb2 Tudor domain ZapB PF06005.12 EEQ39739.1 - 0.026 14.9 5.7 0.026 14.9 5.7 4.3 3 2 1 4 4 4 0 Cell division protein ZapB PACT_coil_coil PF10495.9 EEQ39739.1 - 0.16 12.6 0.0 0.16 12.6 0.0 3.0 2 1 0 2 2 2 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein TSC22 PF01166.18 EEQ39739.1 - 1.2 9.5 9.6 1.1 9.6 2.0 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family Y_phosphatase PF00102.27 EEQ39740.1 - 5.5e-56 189.8 1.7 7.6e-56 189.3 1.7 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EEQ39740.1 - 2.9e-06 27.7 0.0 1.3e-05 25.7 0.0 2.1 2 0 0 2 2 2 1 Rhodanese-like domain DUF2483 PF10656.9 EEQ39740.1 - 0.13 12.5 0.1 0.36 11.1 0.1 1.7 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) Y_phosphatase3 PF13350.6 EEQ39740.1 - 0.14 12.1 0.1 0.42 10.6 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Prenyltrans PF00432.21 EEQ39741.1 - 1.7e-35 120.4 11.4 2.6e-11 43.0 0.7 5.5 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat PI_PP_I PF18363.1 EEQ39741.1 - 0.00088 19.4 0.0 0.049 13.8 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide phosphatase insertion domain SQHop_cyclase_N PF13249.6 EEQ39741.1 - 0.098 11.7 0.0 8.5 5.4 0.0 2.5 2 1 1 3 3 3 0 Squalene-hopene cyclase N-terminal domain UBX PF00789.20 EEQ39742.1 - 7.3e-09 35.7 0.0 3e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 UBX domain MFS_1 PF07690.16 EEQ39743.1 - 4.2e-22 78.6 17.0 7.7e-22 77.7 17.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EEQ39743.1 - 2e-16 60.3 4.3 2e-16 60.3 4.3 2.4 2 1 0 2 2 2 2 Nodulin-like MFS_2 PF13347.6 EEQ39743.1 - 6.8e-08 31.5 18.4 7.3e-08 31.4 3.2 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein DUF4131 PF13567.6 EEQ39743.1 - 0.07 12.8 5.6 0.97 9.1 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Dynamin_N PF00350.23 EEQ39744.1 - 3.3e-16 59.8 0.0 1.3e-15 57.9 0.0 2.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EEQ39744.1 - 3.1e-11 43.3 0.0 1.4e-10 41.3 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ39744.1 - 3.3e-07 30.0 0.6 0.00026 20.6 0.4 2.8 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Roc PF08477.13 EEQ39744.1 - 0.0015 18.8 0.3 3.5 7.9 0.0 3.4 4 0 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 EEQ39744.1 - 0.0038 16.3 2.8 0.012 14.7 0.0 2.6 3 0 0 3 3 3 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 EEQ39744.1 - 0.0061 16.5 1.1 1.8 8.4 0.2 2.9 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 EEQ39744.1 - 0.019 14.6 2.8 0.13 11.9 0.5 3.2 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EEQ39744.1 - 0.045 14.3 0.0 0.29 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EEQ39744.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ureidogly_lyase PF04115.12 EEQ39745.1 - 9.7e-62 208.1 0.1 1.1e-61 207.9 0.1 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Adaptin_binding PF10199.9 EEQ39746.1 - 4e-07 30.7 5.5 4e-06 27.4 3.6 2.9 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 AAA_18 PF13238.6 EEQ39746.1 - 0.11 13.0 0.4 1.4 9.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain Sec15 PF04091.12 EEQ39747.1 - 1.4e-89 300.6 6.6 1.4e-89 300.6 6.6 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF72 PF01904.18 EEQ39747.1 - 0.078 13.1 0.1 0.53 10.4 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function DUF72 Proteasome PF00227.26 EEQ39749.1 - 7.1e-48 162.6 0.1 9.2e-48 162.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EEQ39749.1 - 5.8e-11 41.8 0.1 1e-10 41.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Plant_all_beta PF10532.9 EEQ39749.1 - 0.059 13.7 0.5 0.11 12.8 0.5 1.4 1 0 0 1 1 1 0 Plant specific N-all beta domain Flg_hook PF02120.16 EEQ39749.1 - 0.09 12.7 0.4 55 3.7 0.0 3.1 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK HSP70 PF00012.20 EEQ39750.1 - 4.6e-223 741.8 9.5 5.6e-223 741.5 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ39750.1 - 1.3e-17 63.6 6.0 1.5e-15 56.8 0.2 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 EEQ39750.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EEQ39750.1 - 0.0031 17.9 2.2 0.59 10.6 0.0 3.8 3 1 0 3 3 3 1 Cell division protein FtsA DUF1464 PF07318.12 EEQ39750.1 - 0.013 14.7 0.4 0.04 13.1 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1464) F-box PF00646.33 EEQ39751.1 - 2.8e-08 33.4 0.0 7.6e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EEQ39751.1 - 0.00025 20.8 0.1 0.001 18.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like TPR_2 PF07719.17 EEQ39751.1 - 0.051 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat THUMP PF02926.17 EEQ39752.1 - 4e-23 82.1 0.8 7.6e-23 81.2 0.1 1.7 2 0 0 2 2 2 1 THUMP domain DUF3417 PF11897.8 EEQ39752.1 - 0.075 13.5 0.2 18 5.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3417) DUF1798 PF08807.10 EEQ39752.1 - 3 8.0 7.2 2.2 8.4 0.3 2.8 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) DUF1077 PF06417.12 EEQ39753.1 - 4.6e-45 152.4 3.0 5.7e-45 152.1 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Vps55 PF04133.14 EEQ39754.1 - 5.9e-31 106.9 6.1 6.7e-31 106.7 6.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2108 PF09881.9 EEQ39754.1 - 0.0067 16.4 2.8 0.0067 16.4 2.8 2.8 2 2 2 4 4 4 1 Predicted membrane protein (DUF2108) Oxidored_q2 PF00420.24 EEQ39754.1 - 0.007 16.0 1.4 0.65 9.7 0.0 2.3 2 0 0 2 2 2 2 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF5345 PF17280.2 EEQ39754.1 - 0.076 13.0 1.8 0.098 12.6 0.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5345) Phage_holin_3_6 PF07332.11 EEQ39754.1 - 0.2 11.7 3.6 6 6.9 0.1 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III CAF1C_H4-bd PF12265.8 EEQ39755.1 - 2.4e-19 69.3 0.1 7.6e-19 67.8 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EEQ39755.1 - 2.3e-07 31.4 11.8 1.2 10.1 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39755.1 - 0.013 15.8 0.0 9.9 6.5 0.0 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PHD PF00628.29 EEQ39756.1 - 9e-10 38.3 10.1 9e-10 38.3 10.1 1.9 2 0 0 2 2 2 1 PHD-finger Nore1-SARAH PF16517.5 EEQ39756.1 - 4.8 7.2 7.8 16 5.5 1.0 3.1 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain UPF0047 PF01894.17 EEQ39757.1 - 2.1e-37 127.8 0.0 2.5e-37 127.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 DIT1_PvcA PF05141.12 EEQ39758.1 - 7.2e-94 314.3 0.1 1.3e-93 313.5 0.1 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF2458 PF10454.9 EEQ39758.1 - 0.083 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Pkinase PF00069.25 EEQ39759.1 - 9.7e-63 212.0 0.0 1.3e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39759.1 - 2.3e-29 102.5 0.0 3.4e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ39759.1 - 7.1e-09 35.4 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EEQ39759.1 - 2.1e-08 33.4 1.0 2.6e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EEQ39759.1 - 0.0037 16.6 0.1 0.047 13.0 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EEQ39759.1 - 0.029 13.9 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EEQ39759.1 - 0.057 13.3 0.0 3.6 7.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CBF PF03914.17 EEQ39760.1 - 2e-47 161.4 0.1 2e-47 161.4 0.1 2.9 3 0 0 3 3 3 1 CBF/Mak21 family Ras PF00071.22 EEQ39761.1 - 5.7e-20 71.6 0.3 1.1e-19 70.7 0.3 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EEQ39761.1 - 0.0008 19.6 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EEQ39761.1 - 0.027 15.0 0.0 0.052 14.1 0.0 1.8 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 EEQ39761.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase TniB PF05621.11 EEQ39761.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Pkinase PF00069.25 EEQ39762.1 - 6.8e-61 205.9 0.0 1.5e-60 204.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39762.1 - 2.5e-36 125.3 0.0 4.5e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EEQ39762.1 - 6.2e-23 80.7 9.9 1.8e-12 47.2 3.0 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EEQ39762.1 - 2.9e-17 62.3 41.4 5.3e-11 42.2 14.4 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EEQ39762.1 - 1.3e-12 48.2 1.8 1.3e-12 48.2 1.8 2.9 2 1 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EEQ39762.1 - 2.5e-05 24.5 0.1 5e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 EEQ39762.1 - 7.5e-05 21.8 0.3 0.00018 20.6 0.3 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Uds1 PF15456.6 EEQ39762.1 - 0.086 13.0 2.4 0.27 11.4 0.1 2.6 2 0 0 2 2 2 0 Up-regulated During Septation C1_2 PF03107.16 EEQ39762.1 - 0.89 9.9 26.7 2.6 8.4 6.7 2.7 2 0 0 2 2 2 0 C1 domain zf-RING_9 PF13901.6 EEQ39762.1 - 3.3 7.6 32.6 0.5 10.3 7.5 3.7 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon zinc_ribbon_16 PF17034.5 EEQ39763.1 - 1.3e-26 93.2 10.9 4.5e-26 91.5 10.8 1.9 2 0 0 2 2 2 1 Zinc-ribbon like family zf-rbx1 PF12678.7 EEQ39763.1 - 0.0026 18.0 2.5 0.01 16.1 2.5 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EEQ39763.1 - 0.2 11.3 15.7 0.016 14.8 9.9 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EEQ39763.1 - 0.38 11.7 9.5 5.1 8.1 0.1 4.9 4 1 0 4 4 4 0 WD domain, G-beta repeat Pkinase PF00069.25 EEQ39764.1 - 7.1e-72 241.9 0.0 2.6e-71 240.1 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39764.1 - 3.9e-37 127.9 0.0 7.4e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EEQ39764.1 - 3.6e-09 36.4 1.2 3.6e-09 36.4 1.2 2.8 3 0 0 3 3 3 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 EEQ39764.1 - 0.00052 19.4 0.0 0.0011 18.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ39764.1 - 0.0067 15.8 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ39764.1 - 0.037 14.0 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2325 PF10087.9 EEQ39764.1 - 0.045 13.9 0.1 0.22 11.6 0.1 2.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Pkinase PF00069.25 EEQ39765.1 - 1.6e-68 231.0 0.0 2.6e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39765.1 - 1.5e-31 109.7 0.0 2e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEQ39765.1 - 7.4e-10 39.4 2.3 2e-09 38.0 2.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EEQ39765.1 - 5.3e-06 25.6 0.2 1e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EEQ39765.1 - 0.001 18.7 0.2 1.5 8.4 0.1 2.5 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EEQ39765.1 - 0.012 15.0 0.0 0.03 13.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EEQ39765.1 - 0.012 15.0 0.1 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ39765.1 - 0.03 14.2 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family MRP-L28 PF09812.9 EEQ39767.1 - 1.2e-29 103.5 4.9 1.5e-29 103.2 4.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF1640 PF07798.11 EEQ39767.1 - 0.0051 16.9 1.2 0.0065 16.5 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) JAKMIP_CC3 PF16034.5 EEQ39767.1 - 0.018 15.0 2.3 0.023 14.6 2.1 1.2 1 1 0 1 1 1 0 JAKMIP CC3 domain Flu_NS2 PF00601.19 EEQ39767.1 - 0.074 13.4 0.7 0.12 12.7 0.6 1.5 1 1 0 1 1 1 0 Influenza non-structural protein (NS2) DUF1904 PF08921.11 EEQ39767.1 - 0.11 12.9 0.2 0.19 12.1 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1904) NuA4 PF09340.10 EEQ39768.1 - 1.8e-26 91.8 1.8 3.4e-26 90.9 1.8 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 FadA PF09403.10 EEQ39768.1 - 0.018 15.5 2.1 0.074 13.5 2.1 1.9 1 1 0 1 1 1 0 Adhesion protein FadA Enolase_C PF00113.22 EEQ39769.1 - 1.4e-156 520.3 0.0 2e-156 519.7 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EEQ39769.1 - 1.1e-55 187.3 0.1 2e-55 186.5 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EEQ39769.1 - 6.5e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EEQ39769.1 - 0.017 14.3 0.9 0.041 13.0 0.2 2.0 2 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus Aminotran_5 PF00266.19 EEQ39770.1 - 7.6e-13 48.2 0.0 1.5e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EEQ39770.1 - 0.00073 18.2 0.0 0.0011 17.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EEQ39770.1 - 0.054 12.8 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Clat_adaptor_s PF01217.20 EEQ39771.1 - 1.5e-43 148.2 1.1 1.7e-43 147.9 1.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CBP4 PF07960.11 EEQ39772.1 - 1.4e-51 173.7 0.5 1.7e-51 173.4 0.5 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 EEQ39772.1 - 0.0041 17.0 0.5 0.0063 16.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 LAMTOR PF15454.6 EEQ39772.1 - 0.02 15.5 0.2 0.034 14.7 0.2 1.4 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator MRP-S32 PF10210.9 EEQ39772.1 - 0.021 15.3 3.3 0.04 14.4 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S32 Fungal_trans_2 PF11951.8 EEQ39773.1 - 4.1e-12 45.6 0.3 7.7e-12 44.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ39773.1 - 2.8e-07 30.5 10.7 4.5e-07 29.9 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 EEQ39774.1 - 2e-50 170.5 0.0 2.4e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ39774.1 - 2.1e-18 66.7 0.0 3.1e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ39774.1 - 3.9e-07 29.7 0.0 5e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family HATPase_c PF02518.26 EEQ39775.1 - 1.7e-27 96.2 0.1 3.7e-27 95.1 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EEQ39775.1 - 8.5e-20 71.0 0.7 5.1e-19 68.5 0.1 2.5 2 0 0 2 2 2 1 Response regulator receiver domain Pkinase PF00069.25 EEQ39775.1 - 1.2e-13 51.1 0.0 4e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain HisKA PF00512.25 EEQ39775.1 - 2e-11 43.8 0.0 6.1e-11 42.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 EEQ39775.1 - 3.8e-09 37.2 0.0 1.5e-08 35.2 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Pkinase_Tyr PF07714.17 EEQ39775.1 - 1.8e-05 24.1 0.0 4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase GAF_3 PF13492.6 EEQ39775.1 - 5.1e-05 23.6 0.0 0.00017 21.9 0.0 2.0 1 0 0 1 1 1 1 GAF domain AAA_29 PF13555.6 EEQ39775.1 - 0.00011 21.8 0.1 0.00048 19.8 0.0 2.2 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ39775.1 - 0.011 16.1 0.3 0.11 12.8 0.0 2.7 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EEQ39775.1 - 0.014 15.3 0.1 0.28 11.1 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EEQ39775.1 - 0.025 14.5 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EEQ39775.1 - 0.07 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 EEQ39775.1 - 0.084 13.4 0.2 0.41 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EEQ39775.1 - 0.12 12.9 0.0 0.73 10.4 0.0 2.3 2 0 0 2 2 2 0 ABC transporter HMG_box_2 PF09011.10 EEQ39776.1 - 2.9e-06 27.8 18.8 3.6e-05 24.3 7.3 3.8 2 2 1 3 3 3 2 HMG-box domain HMG_box PF00505.19 EEQ39776.1 - 7.8e-06 26.2 9.6 0.0036 17.7 7.1 3.6 3 2 0 3 3 3 2 HMG (high mobility group) box DUF501 PF04417.12 EEQ39776.1 - 0.0011 18.8 0.2 0.0027 17.5 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF501) DUF5094 PF17015.5 EEQ39776.1 - 0.061 13.4 9.6 0.22 11.6 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) PRKG1_interact PF15898.5 EEQ39776.1 - 0.75 10.7 12.3 0.83 10.6 3.4 2.5 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain SlyX PF04102.12 EEQ39776.1 - 1.1 9.9 3.8 1 10.0 1.6 2.1 2 0 0 2 2 2 0 SlyX FapA PF03961.13 EEQ39776.1 - 1.4 7.4 10.9 0.022 13.4 3.7 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A Aldedh PF00171.22 EEQ39777.1 - 6.6e-151 502.9 0.0 7.5e-151 502.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EEQ39777.1 - 0.005 16.3 0.4 0.038 13.5 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) FlaG PF03646.15 EEQ39777.1 - 0.19 11.9 0.2 0.55 10.4 0.2 1.7 1 0 0 1 1 1 0 FlaG protein Rox3 PF08633.10 EEQ39778.1 - 1.9e-13 51.2 1.3 1.4e-11 45.1 0.0 2.1 1 1 1 2 2 2 2 Rox3 mediator complex subunit Apt1 PF10351.9 EEQ39779.1 - 1.7e-95 320.6 7.1 1.7e-95 320.6 7.1 2.5 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EEQ39779.1 - 5.5e-78 263.0 21.1 1.3e-41 143.1 8.7 3.2 2 1 1 3 3 3 2 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 EEQ39779.1 - 1.7e-77 261.4 31.8 3.7e-77 260.3 31.8 1.6 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_GFWDK PF10347.9 EEQ39779.1 - 3.3e-51 173.5 0.0 9.7e-51 172.0 0.0 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EEQ39779.1 - 1.7e-45 154.7 1.0 6.4e-45 152.8 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 EEQ39779.1 - 2e-24 86.3 0.2 3.6e-22 79.0 0.0 4.2 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Ribosomal_L32e PF01655.18 EEQ39780.1 - 2.4e-48 163.0 2.1 2.8e-48 162.8 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 tRNA-synt_1e PF01406.19 EEQ39780.1 - 0.055 12.8 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 EEQ39781.1 - 1.6e-40 139.1 0.0 2.6e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39781.1 - 9.8e-23 80.7 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ39781.1 - 1.6e-07 31.0 0.0 3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ39781.1 - 0.011 15.0 0.2 0.037 13.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ39781.1 - 0.028 14.3 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EEQ39781.1 - 0.094 12.2 0.1 0.23 10.9 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SUR7 PF06687.12 EEQ39782.1 - 2.8e-35 121.9 10.2 3.3e-35 121.7 10.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EEQ39782.1 - 0.0004 20.4 11.6 0.0004 20.4 11.6 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Wzy_C PF04932.15 EEQ39782.1 - 1.7 8.2 6.6 0.53 9.9 2.5 2.0 2 1 0 2 2 2 0 O-Antigen ligase DUF2207 PF09972.9 EEQ39782.1 - 3.8 6.2 5.4 22 3.6 3.8 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Lipase_3 PF01764.25 EEQ39783.1 - 9.1e-07 28.8 0.0 2.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) UPF0258 PF06789.12 EEQ39783.1 - 0.0079 16.3 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0258) Abhydrolase_6 PF12697.7 EEQ39783.1 - 0.0095 16.6 0.0 0.025 15.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EEQ39783.1 - 0.039 13.7 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Phos_pyr_kin PF08543.12 EEQ39784.1 - 8.8e-08 31.8 0.0 1.1e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EEQ39784.1 - 0.0088 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ANAPC4_WD40 PF12894.7 EEQ39785.1 - 7.9e-05 22.9 0.0 0.00027 21.2 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ39785.1 - 0.065 14.1 0.1 0.52 11.3 0.0 2.6 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 EEQ39786.1 - 3.3e-11 42.8 15.3 4.2e-11 42.5 11.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EEQ39786.1 - 1.4e-08 34.5 2.6 1.4e-08 34.5 2.6 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EEQ39786.1 - 5.1e-08 32.8 11.0 1.5e-07 31.3 5.4 2.9 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEQ39786.1 - 7.1e-08 32.2 11.5 7.1e-08 32.2 11.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ39786.1 - 4.4e-07 29.7 12.4 2.1e-06 27.5 8.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ39786.1 - 7.8e-07 29.2 14.0 2.7e-06 27.4 10.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EEQ39786.1 - 1.2e-06 28.3 14.0 3e-05 23.8 9.6 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ39786.1 - 1.3e-06 28.2 13.6 6.1e-06 26.1 10.1 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EEQ39786.1 - 2.5e-06 27.7 11.3 2.5e-06 27.7 11.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 EEQ39786.1 - 2.7e-05 24.2 7.4 2.7e-05 24.2 7.4 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 SAP PF02037.27 EEQ39786.1 - 4e-05 23.3 1.4 6.8e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 SAP domain zf-rbx1 PF12678.7 EEQ39786.1 - 0.00011 22.4 6.4 0.00011 22.4 6.4 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain U-box PF04564.15 EEQ39786.1 - 0.0039 17.3 0.1 0.5 10.6 0.0 2.6 2 0 0 2 2 2 1 U-box domain zf-WRNIP1_ubi PF18279.1 EEQ39786.1 - 0.033 14.8 1.1 0.17 12.6 0.1 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-Di19 PF05605.12 EEQ39786.1 - 0.047 14.0 7.7 0.12 12.7 0.4 2.7 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-ANAPC11 PF12861.7 EEQ39786.1 - 1.1 9.3 4.7 0.73 9.9 2.5 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 EEQ39786.1 - 2.2 8.5 9.4 0.48 10.6 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) YdjO PF14169.6 EEQ39786.1 - 3.9 7.3 6.5 17 5.2 2.2 2.7 2 0 0 2 2 2 0 Cold-inducible protein YdjO zf-Nse PF11789.8 EEQ39786.1 - 4.3 7.2 11.3 1 9.2 5.8 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 EEQ39786.1 - 5.2 7.0 11.3 0.19 11.6 2.6 2.5 3 0 0 3 3 2 0 RING/Ubox like zinc-binding domain Form_Nir_trans PF01226.17 EEQ39788.1 - 4.1e-61 206.4 22.0 5e-61 206.1 22.0 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter DEAD PF00270.29 EEQ39789.1 - 1e-37 129.6 0.8 1.8e-37 128.8 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ39789.1 - 2.1e-32 111.8 2.4 3.8e-30 104.5 0.1 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39789.1 - 3.9e-07 30.2 2.5 5.9e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit CDC45 PF02724.14 EEQ39789.1 - 0.019 13.3 4.2 0.027 12.8 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EEQ39789.1 - 1.6 9.2 6.4 3.2 8.2 6.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 EEQ39789.1 - 2.4 6.8 6.5 3.8 6.2 6.5 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EEQ39789.1 - 3.8 6.2 9.8 5 5.9 3.7 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter RNA_polI_A34 PF08208.11 EEQ39789.1 - 6 6.9 18.7 0.078 13.1 11.1 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Mpv17_PMP22 PF04117.12 EEQ39790.1 - 6.8e-09 35.8 4.0 1.9e-08 34.4 4.0 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.16 EEQ39791.1 - 1.9e-40 138.9 32.4 1.9e-40 138.9 32.4 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4191 PF13829.6 EEQ39791.1 - 3.1 7.1 5.1 15 4.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) YL1 PF05764.13 EEQ39792.1 - 4.1e-42 145.0 43.5 4.1e-42 145.0 43.5 4.9 3 2 1 4 4 4 1 YL1 nuclear protein YL1_C PF08265.11 EEQ39792.1 - 4.1e-10 39.3 0.3 8.3e-10 38.3 0.0 1.7 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Methyltransf_23 PF13489.6 EEQ39793.1 - 1.3e-21 77.2 0.0 1.9e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ39793.1 - 1.8e-16 60.6 0.0 4.1e-16 59.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ39793.1 - 1.6e-14 54.0 0.0 3.6e-14 52.8 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ39793.1 - 9.1e-14 51.9 0.0 1.7e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ39793.1 - 4e-12 46.7 0.0 7.1e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EEQ39793.1 - 1.9e-09 37.2 0.0 3.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EEQ39793.1 - 2.3e-06 27.2 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EEQ39793.1 - 3.6e-06 26.5 0.0 5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EEQ39793.1 - 8.5e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW NodS PF05401.11 EEQ39793.1 - 2.5e-05 24.0 0.0 3.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EEQ39793.1 - 0.00024 20.7 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EEQ39793.1 - 0.00083 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EEQ39793.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_18 PF12847.7 EEQ39793.1 - 0.0089 16.0 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 EEQ39793.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase TehB PF03848.14 EEQ39793.1 - 0.045 13.2 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 EEQ39793.1 - 0.078 12.0 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pox_MCEL PF03291.16 EEQ39793.1 - 0.12 11.5 0.0 0.51 9.4 0.0 1.9 2 0 0 2 2 2 0 mRNA capping enzyme PCMT PF01135.19 EEQ39793.1 - 0.14 11.9 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DnaJ_C PF01556.18 EEQ39794.1 - 3.1e-42 144.2 0.1 4e-42 143.8 0.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ39794.1 - 7.6e-27 93.2 2.6 1.4e-26 92.4 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EEQ39794.1 - 5.9e-14 52.2 21.0 1e-13 51.4 21.0 1.4 1 0 0 1 1 1 1 DnaJ central domain Malate_DH PF12434.8 EEQ39794.1 - 0.028 14.4 0.2 0.075 13.1 0.2 1.8 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Anti-TRAP PF15777.5 EEQ39794.1 - 1.8 8.6 17.0 0.35 10.8 3.9 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein CAP_N PF01213.19 EEQ39795.1 - 6.8e-115 383.9 4.3 1.2e-114 383.1 4.3 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EEQ39795.1 - 3e-52 176.4 6.6 4.4e-52 175.8 6.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Actin PF00022.19 EEQ39796.1 - 7.8e-50 169.7 0.0 3.7e-28 98.3 0.0 2.9 1 1 1 2 2 2 2 Actin SopE_GEF PF07487.13 EEQ39796.1 - 7.3 6.7 7.8 0.62 10.2 0.8 2.7 2 1 0 2 2 2 0 SopE GEF domain Methyltr_RsmB-F PF01189.17 EEQ39797.1 - 2.2e-80 269.0 0.0 3.7e-80 268.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EEQ39797.1 - 1.1e-08 35.4 0.1 8.4e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EEQ39797.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Gcd10p PF04189.13 EEQ39798.1 - 8.9e-98 327.1 3.3 1.1e-97 326.8 3.3 1.1 1 0 0 1 1 1 1 Gcd10p family AvrM_N PF18247.1 EEQ39798.1 - 0.075 13.0 0.3 0.25 11.3 0.3 1.9 1 0 0 1 1 1 0 Flax-rust effector AvrM N-terminal domain MTS PF05175.14 EEQ39799.1 - 2.8e-11 43.2 0.0 1.2e-10 41.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EEQ39799.1 - 9e-10 38.5 0.0 1.8e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ39799.1 - 7.2e-09 36.3 0.0 6e-08 33.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 EEQ39799.1 - 0.0045 17.6 0.0 0.014 16.0 0.0 1.9 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_11 PF08241.12 EEQ39799.1 - 0.011 16.4 0.0 0.047 14.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ39799.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family N6_Mtase PF02384.16 EEQ39799.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase UPF0020 PF01170.18 EEQ39799.1 - 0.099 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.6 EEQ39799.1 - 0.11 12.4 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EEQ39799.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain S4 PF01479.25 EEQ39800.1 - 2e-14 53.0 0.0 4.1e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 EEQ39800.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 S4 domain Eaf7 PF07904.13 EEQ39801.1 - 1.8e-14 54.0 12.2 5e-13 49.3 12.1 3.0 1 1 0 1 1 1 1 Chromatin modification-related protein EAF7 AA_permease PF00324.21 EEQ39802.1 - 2.4e-124 415.6 50.2 2.8e-124 415.3 50.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ39802.1 - 6e-32 111.0 55.7 8.7e-32 110.5 55.7 1.3 1 0 0 1 1 1 1 Amino acid permease SUN PF03856.13 EEQ39803.1 - 1e-94 316.6 18.5 1.6e-94 316.0 18.5 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF1221 PF06760.11 EEQ39803.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) Macoilin PF09726.9 EEQ39803.1 - 0.47 8.9 6.3 0.64 8.5 6.3 1.3 1 0 0 1 1 1 0 Macoilin family DUF1180 PF06679.12 EEQ39803.1 - 3.1 8.2 14.0 6.8 7.1 14.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Gar1 PF04410.14 EEQ39804.1 - 7.4e-48 162.2 2.8 7.4e-48 162.2 2.8 2.8 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region MutS_V PF00488.21 EEQ39805.1 - 5.7e-67 225.4 0.0 7.6e-67 225.0 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EEQ39805.1 - 0.00023 21.4 0.7 0.0013 19.0 0.1 2.2 2 1 0 2 2 2 1 MutS domain III AAA_29 PF13555.6 EEQ39805.1 - 0.074 12.8 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MutS_I PF01624.20 EEQ39806.1 - 1.3e-22 80.1 0.0 3.2e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 EEQ39806.1 - 2.5e-20 73.5 4.3 8.1e-20 71.8 4.0 1.9 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EEQ39806.1 - 1.4e-12 48.1 0.0 2.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain II CCDC92 PF14916.6 EEQ39806.1 - 0.035 13.9 0.2 0.035 13.9 0.2 2.4 3 0 0 3 3 3 0 Coiled-coil domain of unknown function Nmad5 PF18757.1 EEQ39806.1 - 0.065 13.4 0.3 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 Nucleotide modification associated domain 5 CK2S PF15011.6 EEQ39806.1 - 0.12 12.3 0.9 0.4 10.6 0.1 2.2 2 0 0 2 2 2 0 Casein Kinase 2 substrate N-SET PF11764.8 EEQ39807.1 - 1.1e-50 172.1 1.1 1.1e-50 172.1 1.1 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 EEQ39807.1 - 1.2e-19 71.4 0.2 1.2e-19 71.4 0.2 2.7 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.8 EEQ39808.1 - 1.1e-27 95.5 2.2 1.1e-27 95.5 2.2 1.7 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated ETC_C1_NDUFA4 PF04800.12 EEQ39810.1 - 3.9e-32 110.4 0.9 5.3e-32 109.9 0.9 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region ORC6 PF05460.13 EEQ39811.1 - 5.6e-79 266.0 0.0 6.9e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) Trypsin_2 PF13365.6 EEQ39812.1 - 4.5e-20 73.1 0.0 7.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain PDZ_1 PF12812.7 EEQ39812.1 - 1.4e-12 47.5 1.1 2.7e-12 46.5 0.0 2.1 3 0 0 3 3 3 1 PDZ-like domain PDZ_6 PF17820.1 EEQ39812.1 - 4.7e-10 39.1 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EEQ39812.1 - 6.1e-08 32.9 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EEQ39812.1 - 1.5e-07 31.7 0.0 2.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 PDZ domain Trypsin PF00089.26 EEQ39812.1 - 0.00011 22.1 0.0 0.00032 20.6 0.0 1.7 1 1 0 1 1 1 1 Trypsin Peptidase_S7 PF00949.21 EEQ39812.1 - 0.0036 17.1 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 EEQ39812.1 - 0.0063 16.1 0.2 0.0091 15.6 0.2 1.2 1 0 0 1 1 1 1 Putative peptidase (DUF31) Tricorn_PDZ PF14685.6 EEQ39812.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 EEQ39812.1 - 0.024 13.3 0.3 0.058 12.1 0.0 1.6 2 0 0 2 2 2 0 Peptidase S46 PDZ_1 PF12812.7 EEQ39814.1 - 2.4e-10 40.3 0.0 4.9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 PDZ-like domain PDZ_1 PF12812.7 EEQ39815.1 - 3.2e-22 78.3 0.1 7.8e-22 77.1 0.0 1.7 2 0 0 2 2 2 1 PDZ-like domain PDZ_2 PF13180.6 EEQ39815.1 - 0.0016 18.7 0.0 0.72 10.2 0.0 2.3 2 0 0 2 2 2 2 PDZ domain Frag1 PF10277.9 EEQ39816.1 - 2.2e-37 128.7 17.5 2.2e-37 128.7 17.5 2.8 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family ATP-synt PF00231.19 EEQ39817.1 - 3.2e-72 243.6 5.7 3.6e-72 243.4 5.7 1.0 1 0 0 1 1 1 1 ATP synthase EMP70 PF02990.16 EEQ39818.1 - 3.5e-147 491.2 15.0 4.6e-147 490.8 15.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TPR_2 PF07719.17 EEQ39819.1 - 8.9e-28 94.1 16.1 0.00014 21.7 0.1 10.8 11 0 0 11 11 11 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ39819.1 - 1.6e-27 95.5 14.1 5.8e-22 77.7 0.9 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EEQ39819.1 - 1.2e-25 88.2 18.9 8.8e-06 25.3 0.0 9.5 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ39819.1 - 9.7e-19 66.0 10.6 0.0091 16.1 0.0 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ39819.1 - 4.1e-17 62.2 0.9 0.026 14.8 0.1 7.4 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ39819.1 - 4.7e-17 61.4 3.6 0.04 13.6 0.0 7.8 6 1 2 8 8 8 5 TPR repeat TPR_16 PF13432.6 EEQ39819.1 - 9e-15 55.0 5.8 0.0019 18.8 0.0 5.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ39819.1 - 4.1e-14 52.5 0.1 9.7e-05 22.4 0.0 4.2 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ39819.1 - 3.3e-13 49.0 9.0 0.05 14.0 0.2 9.3 9 1 1 10 10 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ39819.1 - 8.1e-11 42.3 3.6 0.21 12.1 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ39819.1 - 2.2e-09 37.4 2.8 1.1 10.2 0.0 7.4 5 3 3 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ39819.1 - 4e-08 32.7 0.8 1.6 8.9 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ39819.1 - 0.00052 20.5 7.6 0.87 10.4 0.0 6.8 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_3 PF07720.12 EEQ39819.1 - 0.02 14.9 0.9 4.8 7.3 0.2 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.20 EEQ39819.1 - 0.26 11.6 1.8 0.91 9.9 0.0 2.9 3 0 0 3 3 3 0 PPR repeat TPR_10 PF13374.6 EEQ39819.1 - 3.5 7.6 5.9 13 5.8 0.0 4.7 8 0 0 8 8 8 0 Tetratricopeptide repeat PH PF00169.29 EEQ39820.1 - 4.7e-15 56.0 0.2 7e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.28 EEQ39820.1 - 2.9e-09 36.4 0.0 7.4e-09 35.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ39820.1 - 1.9e-08 34.0 0.0 3.7e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ39820.1 - 1.9e-06 27.4 0.1 5e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SAM_2 PF07647.17 EEQ39820.1 - 3.7e-06 26.9 0.0 9e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EEQ39820.1 - 0.0033 17.8 0.1 0.0068 16.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MFS_1 PF07690.16 EEQ39821.1 - 4.8e-35 121.1 15.0 4.8e-35 121.1 15.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 EEQ39821.1 - 0.4 10.5 2.9 0.59 10.0 0.3 2.7 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SpoVAB PF13782.6 EEQ39821.1 - 1.6 9.1 6.1 0.15 12.4 0.6 2.2 2 1 1 3 3 3 0 Stage V sporulation protein AB COX17 PF05051.13 EEQ39823.1 - 0.005 17.2 2.2 0.0098 16.2 2.2 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) CHCH PF06747.13 EEQ39823.1 - 0.027 14.6 4.3 0.043 14.0 4.3 1.4 1 0 0 1 1 1 0 CHCH domain Rick_17kDa_Anti PF05433.15 EEQ39824.1 - 1.1e-08 34.7 10.4 2.2e-08 33.8 10.4 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain PT-VENN PF04829.13 EEQ39824.1 - 0.15 12.2 3.4 1.7 8.8 0.1 2.5 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif Glt_symporter PF03616.14 EEQ39824.1 - 0.3 9.7 0.1 0.41 9.3 0.1 1.1 1 0 0 1 1 1 0 Sodium/glutamate symporter TraT PF05818.12 EEQ39824.1 - 3 7.5 8.8 0.074 12.7 2.1 1.7 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein CTU2 PF10288.9 EEQ39825.1 - 8.7e-19 67.8 0.1 8.7e-19 67.8 0.1 1.9 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 DNA_pol_A_exo1 PF01612.20 EEQ39825.1 - 0.023 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 3'-5' exonuclease zinc_ribbon_15 PF17032.5 EEQ39825.1 - 0.086 13.6 2.9 1.4 9.7 0.8 2.6 3 0 0 3 3 3 0 zinc-ribbon family Zn-ribbon_8 PF09723.10 EEQ39825.1 - 2.8 8.1 6.3 6.4 7.0 2.6 2.5 2 0 0 2 2 2 0 Zinc ribbon domain Apc15p PF05841.11 EEQ39826.1 - 3.1e-09 37.7 0.2 1.3e-08 35.7 0.2 1.9 1 1 0 1 1 1 1 Apc15p protein DSPc PF00782.20 EEQ39827.1 - 5.8e-26 90.9 0.0 1.5e-24 86.3 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EEQ39827.1 - 0.00027 21.2 0.0 0.00051 20.3 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain HECT_2 PF09814.9 EEQ39827.1 - 0.0095 14.8 1.7 0.57 9.0 0.2 2.1 1 1 1 2 2 2 2 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Y_phosphatase PF00102.27 EEQ39827.1 - 0.038 13.6 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.14 EEQ39827.1 - 0.1 12.8 1.8 0.53 10.5 1.8 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf_UBZ PF18439.1 EEQ39827.1 - 0.14 11.8 2.6 1.3 8.7 0.4 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger RIG-I_C-RD PF11648.8 EEQ39827.1 - 0.27 11.5 3.4 7.4 6.8 0.3 2.4 1 1 0 2 2 2 0 C-terminal domain of RIG-I zf-3CxxC_2 PF17180.4 EEQ39827.1 - 0.33 11.7 5.1 1.6 9.5 1.5 2.6 2 0 0 2 2 2 0 Zinc-binding domain zinc_ribbon_4 PF13717.6 EEQ39827.1 - 0.46 10.4 4.5 7 6.7 0.5 3.0 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 EEQ39827.1 - 0.63 10.1 3.3 18 5.4 3.3 2.3 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_10 PF18414.1 EEQ39827.1 - 5.9 6.5 6.0 0.61 9.7 0.9 2.0 2 0 0 2 2 2 0 C2H2 type zinc-finger Sugar_tr PF00083.24 EEQ39828.1 - 3.5e-52 177.8 7.7 3.9e-52 177.6 7.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DcpS_C PF11969.8 EEQ39829.1 - 2.1e-25 89.4 1.4 3e-25 88.9 1.4 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2HE PF16278.5 EEQ39829.1 - 1.8e-20 73.1 0.4 4e-20 72.0 0.4 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger HIT PF01230.23 EEQ39829.1 - 1.2e-15 58.1 0.2 3e-15 56.7 0.1 1.7 2 0 0 2 2 2 1 HIT domain CRM1_C PF08767.11 EEQ39829.1 - 0.05 12.8 0.2 0.089 11.9 0.2 1.3 1 0 0 1 1 1 0 CRM1 C terminal zf-C2H2_4 PF13894.6 EEQ39829.1 - 0.19 12.7 0.1 0.19 12.7 0.1 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger Pkr1 PF08636.10 EEQ39830.1 - 4.2e-29 100.5 8.9 5.1e-29 100.2 8.9 1.1 1 0 0 1 1 1 1 ER protein Pkr1 zf-RING_4 PF14570.6 EEQ39831.1 - 1.9e-16 59.6 8.0 3.8e-16 58.6 8.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 EEQ39831.1 - 1e-07 31.6 0.0 2.5e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.11 EEQ39831.1 - 0.0002 21.3 2.3 0.00044 20.2 2.3 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.6 EEQ39831.1 - 0.00029 20.6 3.2 0.00029 20.6 3.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ39831.1 - 0.03 14.2 3.7 0.065 13.1 3.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EEQ39831.1 - 0.057 13.3 5.0 0.13 12.2 5.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ39831.1 - 0.4 11.1 4.8 0.87 10.0 4.8 1.6 1 0 0 1 1 1 0 Ring finger domain FYDLN_acid PF09538.10 EEQ39831.1 - 5.6 7.7 12.4 0.63 10.7 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) Mitoc_L55 PF09776.9 EEQ39831.1 - 9.2 6.0 10.5 8.1 6.2 2.3 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L55 hEGF PF12661.7 EEQ39833.1 - 1.2 9.9 3.2 0.93 10.2 1.2 1.9 2 0 0 2 2 2 0 Human growth factor-like EGF COMPASS-Shg1 PF05205.12 EEQ39835.1 - 0.056 14.2 1.9 0.62 10.8 0.0 2.9 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 tRNA-synt_1 PF00133.22 EEQ39836.1 - 2.5e-153 511.5 0.0 3.3e-153 511.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EEQ39836.1 - 2.7e-19 69.2 0.0 4.9e-13 48.6 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EEQ39836.1 - 3.7e-19 69.2 0.0 6.2e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.6 EEQ39836.1 - 0.00022 20.8 0.0 0.00035 20.2 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 Citrate_synt PF00285.21 EEQ39837.1 - 1.4e-99 333.6 0.0 1.6e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Exo5 PF09810.9 EEQ39838.1 - 7e-27 94.9 0.0 2.8e-26 92.9 0.0 1.9 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EEQ39838.1 - 2.5e-07 30.9 0.2 1.2e-05 25.4 0.2 2.2 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily DUF1730 PF08331.10 EEQ39838.1 - 0.032 14.1 0.0 0.084 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) DUF3602 PF12223.8 EEQ39839.1 - 0.24 12.0 2.7 0.49 11.0 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3602) ADH_N PF08240.12 EEQ39842.1 - 7.2e-30 103.1 1.0 1.5e-29 102.1 1.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ39842.1 - 5.2e-23 81.5 0.1 8e-23 80.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEQ39842.1 - 7.8e-06 25.5 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EEQ39842.1 - 8.4e-06 26.9 0.0 1.4e-05 26.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EEQ39842.1 - 0.019 15.2 0.1 0.034 14.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain PALP PF00291.25 EEQ39842.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme NTP_transf_3 PF12804.7 EEQ39842.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain AlaDh_PNT_C PF01262.21 EEQ39842.1 - 0.064 12.5 0.1 0.17 11.2 0.1 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 EEQ39842.1 - 0.068 12.7 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 EEQ39842.1 - 0.098 13.4 0.1 0.22 12.2 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_3 PF01494.19 EEQ39842.1 - 0.12 11.5 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Sugar_tr PF00083.24 EEQ39843.1 - 4.4e-85 286.2 20.8 5.2e-85 286.0 20.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ39843.1 - 5e-16 58.6 13.3 5e-16 58.6 13.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily XRN_N PF03159.18 EEQ39844.1 - 6.2e-98 327.0 0.0 7.7e-98 326.7 0.0 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EEQ39845.1 - 3.1e-74 250.5 2.3 3.3e-72 243.9 2.3 2.0 1 1 0 1 1 1 1 Xrn1 helical domain XRN_M PF17846.1 EEQ39846.1 - 3.1e-47 161.5 0.7 3.9e-47 161.2 0.0 1.4 2 0 0 2 2 2 1 Xrn1 helical domain DUF775 PF05603.12 EEQ39847.1 - 0.22 11.0 5.3 0.31 10.6 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) SAP130_C PF16014.5 EEQ39847.1 - 7.2 5.6 12.8 8.8 5.3 12.8 1.0 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus DAGK_cat PF00781.24 EEQ39849.1 - 7.4e-11 41.8 0.0 1.2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain MFS_1 PF07690.16 EEQ39850.1 - 1.3e-36 126.3 33.4 1.3e-36 126.3 33.4 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ39850.1 - 7.8e-06 25.0 14.1 7.8e-06 25.0 14.1 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter UPF0182 PF03699.13 EEQ39850.1 - 0.094 10.8 1.8 0.15 10.2 1.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) CENP-B_dimeris PF09026.10 EEQ39850.1 - 0.2 12.0 1.0 0.38 11.2 1.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TPR_MLP1_2 PF07926.12 EEQ39851.1 - 3.5e-09 36.8 14.4 3.5e-09 36.8 14.4 8.4 3 2 5 8 8 8 3 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.10 EEQ39851.1 - 0.013 15.7 5.2 0.013 15.7 5.2 7.1 3 2 4 7 7 7 0 Fibrinogen alpha/beta chain family SASP PF00269.20 EEQ39851.1 - 0.79 9.8 7.6 0.38 10.8 0.1 4.3 5 0 0 5 5 5 0 Small, acid-soluble spore proteins, alpha/beta type Pox_A_type_inc PF04508.12 EEQ39851.1 - 6.4 6.8 23.0 0.37 10.7 0.4 7.8 10 0 0 10 10 10 0 Viral A-type inclusion protein repeat Suppressor_APC PF11414.8 EEQ39852.1 - 0.044 13.9 0.6 0.044 13.9 0.6 4.6 5 0 0 5 5 5 0 Adenomatous polyposis coli tumour suppressor protein OrfB_IS605 PF01385.19 EEQ39852.1 - 0.13 12.5 16.8 0.37 11.0 1.0 4.5 2 1 1 3 3 3 0 Probable transposase NdhM PF10664.9 EEQ39852.1 - 0.35 11.1 3.6 0.91 9.8 1.1 3.0 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M MtrB PF05440.12 EEQ39852.1 - 3 8.3 4.2 2.4 8.6 0.2 3.0 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B WD40_alt PF14077.6 EEQ39852.1 - 6.7 6.7 11.9 0.26 11.2 0.2 4.5 4 2 2 6 6 6 0 Alternative WD40 repeat motif DUF812 PF05667.11 EEQ39852.1 - 6.9 5.4 87.1 0.32 9.8 16.6 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF812) PIN_4 PF13638.6 EEQ39853.1 - 1.3e-20 74.0 1.9 1.8e-20 73.6 0.4 2.0 2 0 0 2 2 2 1 PIN domain PIN_12 PF16289.5 EEQ39853.1 - 0.58 10.6 4.5 0.2 12.1 0.3 2.5 2 1 0 2 2 2 0 PIN domain AA_permease PF00324.21 EEQ39854.1 - 4.9e-107 358.5 36.1 6.1e-107 358.2 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ39854.1 - 2.2e-24 86.1 36.4 3.1e-24 85.6 36.4 1.2 1 0 0 1 1 1 1 Amino acid permease Nup192 PF11894.8 EEQ39855.1 - 0 1567.6 65.7 0 1567.5 65.7 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 TAN PF11640.8 EEQ39855.1 - 0.96 9.6 4.6 2.6 8.2 0.2 3.5 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair p450 PF00067.22 EEQ39856.1 - 1.8e-64 218.2 0.0 2.4e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF559 PF04480.12 EEQ39856.1 - 0.072 13.0 0.1 0.16 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF559) PEPCK_ATP PF01293.20 EEQ39857.1 - 9.1e-216 717.0 0.0 1.1e-215 716.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase ApoLp-III PF07464.11 EEQ39857.1 - 0.094 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) AAA_33 PF13671.6 EEQ39857.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ39857.1 - 0.2 12.0 0.0 0.5 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Glyco_hydro_3 PF00933.21 EEQ39858.1 - 6.9e-62 209.7 0.0 9e-62 209.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain XPG_I PF00867.18 EEQ39859.1 - 2.6e-24 85.4 0.1 8e-24 83.8 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EEQ39859.1 - 0.0028 18.1 0.1 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 XPG N-terminal domain PTPA PF03095.15 EEQ39860.1 - 3.6e-99 332.0 0.0 4.2e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-RING_2 PF13639.6 EEQ39861.1 - 9.4e-08 32.3 9.4 2.7e-07 30.8 9.4 1.9 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EEQ39861.1 - 3.8e-07 30.2 5.2 1.4e-06 28.4 5.2 2.0 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EEQ39861.1 - 8e-05 22.6 2.6 0.00024 21.1 2.6 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EEQ39861.1 - 0.00015 22.0 7.0 0.00044 20.5 7.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain CpxA_peri PF16527.5 EEQ39861.1 - 0.017 15.5 0.0 0.082 13.3 0.0 2.1 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain zf-RING-like PF08746.11 EEQ39861.1 - 0.037 14.3 7.4 0.088 13.1 7.4 1.7 1 0 0 1 1 1 0 RING-like domain Zn_ribbon_17 PF17120.5 EEQ39861.1 - 0.059 13.0 6.3 0.15 11.7 6.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EEQ39861.1 - 0.081 13.1 7.0 0.17 12.0 7.0 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EEQ39861.1 - 2.5 8.0 9.6 2 8.3 1.0 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 EEQ39861.1 - 3.8 7.5 6.9 21 5.2 6.9 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Fungal_trans PF04082.18 EEQ39862.1 - 3.9e-32 111.3 2.7 3.9e-32 111.3 2.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain PIF1 PF05970.14 EEQ39863.1 - 1e-52 179.5 2.2 4.1e-50 171.0 2.2 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EEQ39863.1 - 2.3e-22 79.6 0.0 3.5e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EEQ39863.1 - 4.4e-08 33.6 0.0 9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 EEQ39863.1 - 1.3e-06 26.7 1.7 1.9e-06 26.1 0.0 2.0 3 0 0 3 3 3 1 Helicase SH3_13 PF18335.1 EEQ39863.1 - 7.8e-05 22.4 0.0 0.00027 20.7 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_7 PF12775.7 EEQ39863.1 - 0.00025 20.6 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 EEQ39863.1 - 0.00064 19.1 0.3 0.0028 16.9 0.3 2.0 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 EEQ39863.1 - 0.001 18.9 0.6 0.005 16.7 0.2 2.4 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EEQ39863.1 - 0.0013 19.0 0.0 0.0039 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ39863.1 - 0.0014 19.0 0.2 0.0044 17.4 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 EEQ39863.1 - 0.0016 18.2 0.7 0.39 10.4 0.0 3.3 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EEQ39863.1 - 0.035 14.6 0.1 0.12 12.9 0.1 2.0 1 0 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 EEQ39863.1 - 0.041 13.7 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ39863.1 - 0.042 13.2 0.2 0.12 11.7 0.2 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family UvrD-helicase PF00580.21 EEQ39863.1 - 0.068 12.7 0.2 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain IstB_IS21 PF01695.17 EEQ39863.1 - 0.11 12.3 0.1 1.8 8.3 0.1 2.9 2 1 0 2 2 2 0 IstB-like ATP binding protein Helicase_RecD PF05127.14 EEQ39863.1 - 0.3 10.9 1.8 0.76 9.6 0.6 2.2 2 1 0 2 2 2 0 Helicase FH2 PF02181.23 EEQ39864.1 - 1.1e-79 268.3 10.2 1.1e-79 268.3 10.2 3.0 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EEQ39864.1 - 2.2e-19 69.9 1.5 2.2e-19 69.9 1.5 3.8 4 0 0 4 4 4 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 EEQ39864.1 - 4.7e-13 49.1 5.3 4.7e-13 49.1 5.3 5.2 5 1 0 5 5 5 2 Diaphanous GTPase-binding Domain FTHFS PF01268.19 EEQ39865.1 - 5.8e-242 803.8 0.1 7.3e-242 803.5 0.1 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EEQ39865.1 - 1.1e-66 223.0 0.6 2.1e-65 218.9 0.1 2.6 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EEQ39865.1 - 9.2e-36 122.6 0.2 2.1e-35 121.5 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain NAD_binding_10 PF13460.6 EEQ39866.1 - 7.7e-41 140.0 1.3 9e-41 139.8 1.3 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EEQ39866.1 - 2.5e-06 27.1 0.5 3.9e-06 26.5 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EEQ39866.1 - 1.5e-05 24.7 1.9 7.5e-05 22.4 1.9 1.8 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EEQ39866.1 - 0.00048 19.2 0.6 0.00062 18.9 0.6 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EEQ39866.1 - 0.001 19.2 0.4 0.0018 18.4 0.4 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.23 EEQ39866.1 - 0.29 11.2 1.9 0.57 10.3 1.9 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain EPL1 PF10513.9 EEQ39867.1 - 6.7e-29 101.3 5.8 6.7e-29 101.3 5.8 4.2 3 1 0 3 3 3 1 Enhancer of polycomb-like Peptidase_C57 PF03290.13 EEQ39867.1 - 0.018 13.8 0.9 0.033 12.9 0.4 1.5 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase DUF87 PF01935.17 EEQ39867.1 - 0.59 10.2 7.2 0.21 11.7 2.4 2.8 2 1 0 2 2 2 0 Helicase HerA, central domain WD40 PF00400.32 EEQ39868.1 - 1.3e-05 25.8 5.6 0.16 12.9 0.5 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Med26_C PF15693.5 EEQ39869.1 - 0.015 15.5 1.6 0.017 15.3 1.6 1.0 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal Pkinase PF00069.25 EEQ39870.1 - 9.8e-61 205.4 0.0 9.8e-61 205.4 0.0 2.2 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ39870.1 - 1.3e-29 103.2 0.0 1.3e-29 103.2 0.0 2.2 2 1 0 2 2 1 1 Protein tyrosine kinase DDHD PF02862.17 EEQ39870.1 - 0.0027 17.9 9.7 0.0051 17.0 9.7 1.5 1 0 0 1 1 1 1 DDHD domain Mitofilin PF09731.9 EEQ39870.1 - 0.0049 15.8 18.8 0.0064 15.4 18.8 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein PAT1 PF09770.9 EEQ39870.1 - 0.0058 15.0 40.4 0.0075 14.6 40.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 EEQ39870.1 - 0.07 11.9 24.4 0.096 11.4 24.4 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EEQ39870.1 - 0.08 12.0 19.6 0.11 11.5 19.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 eIF-3_zeta PF05091.12 EEQ39870.1 - 0.17 10.8 24.8 0.24 10.3 24.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Dapper PF15268.6 EEQ39870.1 - 0.23 10.3 23.0 0.29 10.0 23.0 1.0 1 0 0 1 1 1 0 Dapper Pkinase_fungal PF17667.1 EEQ39870.1 - 0.38 9.5 14.5 12 4.5 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase SPX PF03105.19 EEQ39870.1 - 0.46 10.4 18.0 0.59 10.0 18.0 1.1 1 0 0 1 1 1 0 SPX domain DUF4045 PF13254.6 EEQ39870.1 - 0.78 9.3 17.7 1.1 8.9 17.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.7 EEQ39870.1 - 1 7.4 21.0 1.5 6.8 21.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 EEQ39870.1 - 1.4 5.9 22.5 1.8 5.6 22.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Exonuc_VII_L PF02601.15 EEQ39870.1 - 1.4 8.4 22.4 2 7.9 22.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Membralin PF09746.9 EEQ39870.1 - 1.8 7.6 16.0 1.7 7.6 13.5 2.0 2 0 0 2 2 2 0 Tumour-associated protein NPR3 PF03666.13 EEQ39870.1 - 1.9 7.2 20.8 2.8 6.6 20.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Gti1_Pac2 PF09729.9 EEQ39870.1 - 2.2 8.4 17.7 3.8 7.6 17.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2828 PF11443.8 EEQ39870.1 - 2.2 6.3 20.2 3.1 5.8 20.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Macoilin PF09726.9 EEQ39870.1 - 2.7 6.4 18.6 3.8 5.9 18.6 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 EEQ39870.1 - 3.9 5.6 21.5 5.6 5.1 21.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 EEQ39870.1 - 4.4 6.0 18.2 6.4 5.4 18.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 EEQ39870.1 - 5.2 6.8 23.4 7.9 6.2 23.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM76 PF16046.5 EEQ39870.1 - 5.5 6.3 25.6 8.5 5.6 25.6 1.2 1 0 0 1 1 1 0 FAM76 protein DUF1387 PF07139.11 EEQ39870.1 - 6.4 6.4 22.5 10 5.7 22.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Aminotran_1_2 PF00155.21 EEQ39871.1 - 2e-49 168.7 0.0 2.6e-49 168.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEQ39871.1 - 3.5e-06 25.8 0.0 6.1e-06 25.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EEQ39871.1 - 0.0024 17.2 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 EEQ39871.1 - 0.01 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 0 Allinase NDT80_PhoG PF05224.12 EEQ39872.1 - 6.6e-16 59.1 1.0 2.6e-13 50.6 0.0 2.5 1 1 1 2 2 2 2 NDT80 / PhoG like DNA-binding family Aldolase_II PF00596.21 EEQ39873.1 - 3.1e-42 144.6 0.1 3.8e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 EEQ39874.1 - 3.4e-25 88.7 36.0 3.4e-25 88.7 36.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily SHOCT PF09851.9 EEQ39874.1 - 0.99 9.2 5.3 0.99 9.2 1.1 2.3 2 0 0 2 2 2 0 Short C-terminal domain Zn_clus PF00172.18 EEQ39875.1 - 1.7e-07 31.3 6.3 3.3e-07 30.3 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.19 EEQ39876.1 - 7.3e-41 139.5 0.0 3e-40 137.5 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EEQ39876.1 - 1.1e-16 60.6 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Shikimate_DH PF01488.20 EEQ39876.1 - 0.056 13.5 0.0 0.29 11.2 0.0 2.1 2 2 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Fer2_3 PF13085.6 EEQ39877.1 - 1.5e-32 111.8 0.1 2.9e-32 110.9 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EEQ39877.1 - 2.3e-09 37.6 8.0 2.3e-09 37.6 8.0 2.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EEQ39877.1 - 1.5e-08 35.0 23.3 1.6e-07 31.6 8.8 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EEQ39877.1 - 9.1e-08 32.1 3.3 9.1e-08 32.1 3.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 EEQ39877.1 - 0.00092 19.8 5.0 0.00092 19.8 5.0 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EEQ39877.1 - 0.0078 16.1 1.5 0.0078 16.1 1.5 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 EEQ39877.1 - 0.23 11.7 12.7 0.13 12.4 8.1 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain PALP PF00291.25 EEQ39878.1 - 2.5e-40 138.7 0.0 3.1e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3506 PF12014.8 EEQ39878.1 - 0.057 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Globin PF00042.22 EEQ39879.1 - 2e-07 31.6 0.0 4.3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 EEQ39879.1 - 2.6e-07 30.9 0.0 5.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EEQ39879.1 - 1.7e-06 28.6 0.0 0.0001 22.9 0.0 3.0 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 EEQ39879.1 - 0.00058 19.8 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 Protoglobin NAD_binding_6 PF08030.12 EEQ39879.1 - 0.12 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain NMO PF03060.15 EEQ39880.1 - 1e-49 169.7 0.0 2.5e-49 168.5 0.0 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EEQ39880.1 - 1.1e-08 34.5 0.0 0.00044 19.4 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain MRP_L53 PF10780.9 EEQ39881.1 - 5.6e-17 61.7 1.0 7.7e-17 61.2 1.0 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 TENA_THI-4 PF03070.16 EEQ39882.1 - 5.4e-15 55.8 0.1 6.5e-15 55.5 0.1 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Stealth_CR3 PF17102.5 EEQ39882.1 - 0.042 13.8 0.1 0.099 12.6 0.1 1.6 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 PTPLA PF04387.14 EEQ39884.1 - 2.3e-12 47.0 12.5 4.2e-12 46.1 12.5 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DnaJ PF00226.31 EEQ39885.1 - 3e-14 52.9 0.4 6.3e-14 51.8 0.4 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4229 PF14012.6 EEQ39885.1 - 1.7 8.8 7.7 4.4 7.5 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) SAPS PF04499.15 EEQ39886.1 - 8.6e-138 460.2 9.9 8.6e-138 460.2 9.9 2.4 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein YPEB PF14620.6 EEQ39886.1 - 0.0041 16.5 0.5 0.0081 15.5 0.5 1.5 1 0 0 1 1 1 1 YpeB sporulation Post_transc_reg PF13797.6 EEQ39886.1 - 0.06 13.2 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 Post-transcriptional regulator YABBY PF04690.13 EEQ39886.1 - 6.4 7.3 5.8 1.6 9.3 0.7 2.5 2 0 0 2 2 2 0 YABBY protein BIR PF00653.21 EEQ39887.1 - 1.5e-33 115.2 2.2 9.2e-20 71.1 1.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain V-ATPase_H_C PF11698.8 EEQ39888.1 - 3.5e-28 98.1 0.4 5e-28 97.6 0.4 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 EEQ39888.1 - 0.002 17.5 1.8 0.0027 17.0 0.1 1.9 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 EEQ39889.1 - 1.4e-29 103.4 5.4 1.7e-29 103.1 5.4 1.0 1 0 0 1 1 1 1 V-ATPase subunit H GTP_EFTU PF00009.27 EEQ39890.1 - 1.9e-44 151.5 0.1 3e-44 150.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEQ39890.1 - 1.4e-11 44.7 0.1 3.9e-11 43.3 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EEQ39890.1 - 8.9e-06 25.8 0.1 0.00079 19.5 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase SNO PF01174.19 EEQ39890.1 - 0.037 13.9 1.7 0.086 12.7 0.3 2.3 3 0 0 3 3 3 0 SNO glutamine amidotransferase family SRPRB PF09439.10 EEQ39890.1 - 0.058 12.8 1.6 1.6 8.2 0.0 2.8 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF3896 PF13035.6 EEQ39890.1 - 0.11 12.6 1.0 0.42 10.8 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) SMC_N PF02463.19 EEQ39890.1 - 0.12 11.8 0.6 0.75 9.2 0.1 2.5 1 1 2 3 3 3 0 RecF/RecN/SMC N terminal domain Roc PF08477.13 EEQ39890.1 - 0.13 12.5 0.1 26 5.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Syntaxin-18_N PF10496.9 EEQ39891.1 - 1.6e-11 44.3 0.0 1.6e-11 44.3 0.0 3.3 3 2 2 5 5 5 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EEQ39891.1 - 0.0043 17.0 0.2 0.0043 17.0 0.2 2.4 3 0 0 3 3 3 1 SNARE domain Oxidored_nitro PF00148.19 EEQ39891.1 - 0.096 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase IL17R_fnIII_D2 PF16578.5 EEQ39891.1 - 0.91 10.1 5.0 0.45 11.1 0.7 2.7 1 1 2 3 3 3 0 Interleukin 17 receptor D Methyltransf_3 PF01596.17 EEQ39892.1 - 1.4e-11 44.0 0.0 1.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EEQ39892.1 - 1.1e-09 39.2 0.0 1.6e-09 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EEQ39892.1 - 7.5e-05 22.5 0.0 0.00018 21.3 0.0 1.5 1 1 1 2 2 2 1 Cephalosporin hydroxylase SYF2 PF08231.12 EEQ39893.1 - 7.2e-13 49.2 24.0 1e-11 45.5 16.6 3.0 1 1 1 2 2 2 2 SYF2 splicing factor Pathogen_betaC1 PF09593.10 EEQ39893.1 - 0.17 11.8 1.0 0.42 10.6 0.1 1.9 2 0 0 2 2 2 0 Beta-satellite pathogenicity beta C1 protein LptF_LptG PF03739.14 EEQ39893.1 - 0.94 8.3 5.6 1.1 8.0 5.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG LRR_8 PF13855.6 EEQ39894.1 - 1.3e-08 34.4 11.1 0.00078 19.2 0.9 3.9 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EEQ39894.1 - 1.5e-08 34.8 20.4 1.7e-05 25.0 3.2 4.7 2 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EEQ39894.1 - 0.00097 19.0 10.1 1.1 9.4 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 EEQ39894.1 - 0.038 13.5 0.6 0.078 12.5 0.6 1.6 1 0 0 1 1 1 0 Leucine-rich repeat F-box PF00646.33 EEQ39894.1 - 0.044 13.7 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 F-box domain MgtE_N PF03448.17 EEQ39894.1 - 0.049 14.2 0.0 0.1 13.2 0.0 1.5 1 0 0 1 1 1 0 MgtE intracellular N domain F-box-like PF12937.7 EEQ39894.1 - 0.095 12.6 0.1 0.32 10.9 0.1 2.0 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 EEQ39894.1 - 0.099 13.3 12.8 8.8 7.3 0.4 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat FNIP PF05725.12 EEQ39894.1 - 0.19 11.9 3.5 0.48 10.6 0.6 3.0 2 2 1 3 3 3 0 FNIP Repeat ABC_membrane PF00664.23 EEQ39895.1 - 3.4e-59 200.7 0.5 4.5e-59 200.3 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ39895.1 - 2.4e-35 122.0 0.1 6.3e-35 120.7 0.0 1.8 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 EEQ39895.1 - 1.1e-06 28.2 4.8 0.00013 21.5 4.4 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EEQ39895.1 - 6.5e-05 23.2 0.1 0.00049 20.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EEQ39895.1 - 0.00066 19.4 0.1 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EEQ39895.1 - 0.00095 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region DEAD PF00270.29 EEQ39895.1 - 0.0015 18.3 0.0 0.023 14.5 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_21 PF13304.6 EEQ39895.1 - 0.0033 17.3 0.9 0.0076 16.1 0.9 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EEQ39895.1 - 0.0038 17.4 0.0 0.023 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEQ39895.1 - 0.0041 17.1 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 EEQ39895.1 - 0.0066 16.2 0.1 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 EEQ39895.1 - 0.0067 16.4 0.0 0.026 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EEQ39895.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EEQ39895.1 - 0.022 15.2 0.5 0.38 11.2 0.5 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EEQ39895.1 - 0.027 15.0 0.0 0.08 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EEQ39895.1 - 0.072 13.3 0.8 0.69 10.2 0.8 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TniB PF05621.11 EEQ39895.1 - 0.097 12.1 0.0 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_23 PF13476.6 EEQ39895.1 - 2.6 8.5 6.9 0.56 10.7 3.1 2.1 2 1 0 2 2 1 0 AAA domain Glyco_transf_28 PF03033.20 EEQ39896.1 - 3.8e-30 104.8 0.0 1.4e-29 102.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 EEQ39896.1 - 1.5e-21 76.4 0.2 7.4e-15 54.8 0.0 2.8 2 0 0 2 2 2 2 GRAM domain UDPGT PF00201.18 EEQ39896.1 - 5.6e-07 28.7 0.0 1.4e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 EEQ39896.1 - 0.0056 17.2 0.2 0.029 14.9 0.1 2.4 1 1 0 1 1 1 1 PH domain Glyco_tran_28_C PF04101.16 EEQ39896.1 - 0.0066 16.4 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Crinivirus_P26 PF07416.11 EEQ39896.1 - 0.023 14.4 0.1 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Crinivirus P26 protein M20_dimer PF07687.14 EEQ39896.1 - 0.15 12.0 0.0 0.5 10.3 0.0 1.9 1 0 0 1 1 1 0 Peptidase dimerisation domain Abhydrolase_1 PF00561.20 EEQ39897.1 - 2.5e-36 125.6 0.0 3e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ39897.1 - 0.01 16.5 0.0 0.015 15.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fungal_trans PF04082.18 EEQ39899.1 - 3e-09 36.3 0.4 6.8e-09 35.1 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ39899.1 - 4.2e-07 30.0 6.3 4.2e-07 30.0 6.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EEQ39900.1 - 5.1e-16 58.8 14.7 1.1e-05 26.1 0.1 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39900.1 - 1e-09 38.5 0.0 0.097 13.0 0.0 4.5 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ39900.1 - 0.0018 17.3 0.2 0.74 8.7 0.0 2.7 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Talin_middle PF09141.10 EEQ39900.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Talin, middle domain Thioredoxin PF00085.20 EEQ39901.1 - 2.6e-52 175.1 1.0 6.9e-26 90.2 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EEQ39901.1 - 4.1e-25 88.8 1.4 5.8e-18 65.5 1.3 2.9 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EEQ39901.1 - 6.9e-11 42.6 0.3 4.4e-05 23.9 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EEQ39901.1 - 3e-07 30.1 0.1 0.0023 17.3 0.0 2.9 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EEQ39901.1 - 3.7e-06 27.2 0.2 0.47 10.8 0.0 4.5 4 0 0 4 4 4 2 Thioredoxin-like Redoxin PF08534.10 EEQ39901.1 - 4.9e-06 26.3 0.5 0.01 15.5 0.0 3.5 3 0 0 3 3 3 1 Redoxin Thioredoxin_7 PF13899.6 EEQ39901.1 - 7.2e-06 26.1 0.9 0.097 12.9 0.0 4.0 5 1 0 5 5 5 2 Thioredoxin-like Thioredox_DsbH PF03190.15 EEQ39901.1 - 0.0014 18.6 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_9 PF14595.6 EEQ39901.1 - 0.0031 17.3 0.0 0.63 9.8 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 EEQ39901.1 - 0.094 12.5 0.4 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 F plasmid transfer operon protein ColG_sub PF18496.1 EEQ39901.1 - 0.11 12.6 0.2 5.6 7.2 0.0 3.0 4 0 0 4 4 4 0 Collagenase G catalytic helper subdomain Glutaredoxin PF00462.24 EEQ39901.1 - 0.63 10.3 2.6 42 4.5 0.0 3.2 2 1 0 2 2 2 0 Glutaredoxin Ferric_reduct PF01794.19 EEQ39902.1 - 1.2e-20 73.8 9.0 1.2e-20 73.8 9.0 2.7 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EEQ39902.1 - 2.5e-18 66.1 0.2 5.3e-18 65.1 0.2 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EEQ39902.1 - 9.6e-07 29.1 0.0 2.1e-05 24.7 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Actin PF00022.19 EEQ39903.1 - 3.6e-71 239.9 0.0 3.7e-70 236.6 0.0 2.2 1 1 0 1 1 1 1 Actin ECH_2 PF16113.5 EEQ39904.1 - 3e-106 355.7 0.0 4.1e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EEQ39904.1 - 2.5e-27 95.8 0.3 4.3e-26 91.7 0.0 2.6 1 1 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Pec_lyase_N PF04431.13 EEQ39904.1 - 0.14 12.4 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 Pectate lyase, N terminus WD40 PF00400.32 EEQ39905.1 - 0.00011 23.0 0.3 0.26 12.2 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ39905.1 - 0.027 14.8 0.1 3.5 8.0 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 EEQ39905.1 - 0.098 12.6 0.1 9.1 6.3 0.1 2.7 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Sec62 PF03839.16 EEQ39906.1 - 1.7e-73 246.7 3.2 2.4e-73 246.2 3.2 1.2 1 0 0 1 1 1 1 Translocation protein Sec62 Arrestin_C PF02752.22 EEQ39907.1 - 1.7e-18 67.4 0.0 3.5e-16 59.9 0.0 2.9 3 0 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEQ39907.1 - 5.6e-10 39.4 0.0 1.5e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Abhydrolase_1 PF00561.20 EEQ39908.1 - 1.8e-18 67.1 0.0 6.1e-18 65.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ39908.1 - 2.5e-11 43.3 0.0 3.8e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ39908.1 - 2.6e-06 28.2 0.0 3.9e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EEQ39908.1 - 1.6e-05 24.4 0.0 5.7e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF726 PF05277.12 EEQ39908.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) VirJ PF06057.11 EEQ39908.1 - 0.052 13.4 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) ORC3_N PF07034.11 EEQ39908.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Glyco_transf_20 PF00982.21 EEQ39909.1 - 1.1e-147 492.5 0.6 1.5e-147 492.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EEQ39909.1 - 3.3e-73 245.7 0.0 7.8e-73 244.4 0.0 1.6 1 0 0 1 1 1 1 Trehalose-phosphatase SPOB_ab PF14682.6 EEQ39909.1 - 0.043 13.9 0.0 0.13 12.3 0.0 1.8 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal RRM_1 PF00076.22 EEQ39910.1 - 6.8e-88 288.5 3.8 1e-21 76.5 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EEQ39910.1 - 7e-24 83.8 1.4 4.4e-22 78.0 0.1 2.8 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_7 PF16367.5 EEQ39910.1 - 1.5e-06 28.2 0.2 0.74 10.0 0.1 4.5 4 1 0 4 4 4 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EEQ39910.1 - 8e-05 22.6 1.1 0.5 10.4 0.1 4.1 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 EEQ39910.1 - 0.00011 22.7 3.9 0.0076 16.7 0.4 3.2 3 0 0 3 3 3 1 Heat induced stress protein YflT Limkain-b1 PF11608.8 EEQ39910.1 - 0.00097 19.2 0.2 0.28 11.3 0.1 3.3 3 0 0 3 3 3 1 Limkain b1 RRM_occluded PF16842.5 EEQ39910.1 - 0.0061 16.4 0.0 0.042 13.7 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nefa_Nip30_N PF10187.9 EEQ39910.1 - 0.081 13.3 0.4 0.081 13.3 0.4 2.8 3 0 0 3 3 3 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF4078 PF13300.6 EEQ39910.1 - 0.7 10.3 9.0 0.32 11.4 1.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4078) SNF2_N PF00176.23 EEQ39911.1 - 3.4e-59 200.3 0.0 5.7e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 EEQ39911.1 - 1.2e-33 116.0 1.4 1.2e-33 116.0 1.4 2.9 2 0 0 2 2 2 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 EEQ39911.1 - 1.2e-26 92.9 2.4 4.6e-26 91.1 0.2 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.24 EEQ39911.1 - 3.6e-23 81.2 7.4 9.1e-14 51.1 1.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 EEQ39911.1 - 1.5e-19 70.4 0.0 7.9e-19 68.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39911.1 - 2.3e-10 40.8 0.0 1.4e-09 38.2 0.0 2.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EEQ39911.1 - 5.3e-06 25.8 0.4 2.8e-05 23.4 0.0 2.4 2 2 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EEQ39911.1 - 0.00033 20.5 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 EEQ39911.1 - 0.019 15.2 0.0 0.07 13.3 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain RPAP1_N PF08621.10 EEQ39911.1 - 0.022 14.5 0.6 0.18 11.6 0.1 2.7 2 0 0 2 2 2 0 RPAP1-like, N-terminal SLIDE PF09111.10 EEQ39911.1 - 0.023 14.7 0.0 0.13 12.3 0.0 2.3 1 0 0 1 1 1 0 SLIDE ABC_tran PF00005.27 EEQ39912.1 - 8.1e-33 113.8 0.0 2e-15 57.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ39912.1 - 5e-13 49.0 1.7 5.5e-05 22.7 0.0 4.0 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain RLI PF04068.15 EEQ39912.1 - 7e-13 48.2 5.6 1.7e-12 46.9 5.6 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 EEQ39912.1 - 5.1e-11 42.9 6.0 0.1 12.4 0.1 4.2 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 EEQ39912.1 - 1.3e-07 31.2 3.2 1.3e-07 31.2 3.2 2.5 3 0 0 3 3 2 1 4Fe-4S binding domain AAA PF00004.29 EEQ39912.1 - 2.9e-06 27.7 0.0 0.011 16.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EEQ39912.1 - 6.1e-05 22.9 2.5 0.27 10.9 0.0 3.2 3 1 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.6 EEQ39912.1 - 7e-05 23.1 0.0 0.022 15.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain Fer4_6 PF12837.7 EEQ39912.1 - 8.8e-05 22.4 2.7 8.8e-05 22.4 2.7 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Rad17 PF03215.15 EEQ39912.1 - 0.00041 20.3 0.2 0.55 10.1 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain RNA_helicase PF00910.22 EEQ39912.1 - 0.00048 20.5 0.1 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Fer4_21 PF14697.6 EEQ39912.1 - 0.00057 20.0 12.8 0.0013 18.8 12.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain RsgA_GTPase PF03193.16 EEQ39912.1 - 0.00059 19.8 0.0 0.81 9.6 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Fer4_7 PF12838.7 EEQ39912.1 - 0.00061 20.3 6.2 0.0021 18.6 0.2 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_24 PF13479.6 EEQ39912.1 - 0.00075 19.3 0.1 0.23 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEQ39912.1 - 0.0008 19.1 0.3 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.22 EEQ39912.1 - 0.00091 18.9 1.1 0.13 11.9 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 EEQ39912.1 - 0.0013 19.1 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_13 PF13166.6 EEQ39912.1 - 0.0014 17.4 0.8 0.0024 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EEQ39912.1 - 0.0037 17.8 0.0 4.8 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Fer4_2 PF12797.7 EEQ39912.1 - 0.0043 17.1 1.1 0.0043 17.1 1.1 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_10 PF13237.6 EEQ39912.1 - 0.0056 16.8 1.4 0.0056 16.8 1.4 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EEQ39912.1 - 0.0061 16.7 12.0 0.013 15.6 12.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EEQ39912.1 - 0.0071 17.3 0.2 0.0071 17.3 0.2 2.7 2 0 0 2 2 2 1 4Fe-4S double cluster binding domain TsaE PF02367.17 EEQ39912.1 - 0.0079 16.2 0.1 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 EEQ39912.1 - 0.0086 16.6 4.1 0.1 13.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EEQ39912.1 - 0.01 15.8 0.6 1.7 8.5 0.0 2.7 3 0 0 3 3 2 0 NACHT domain Thymidylate_kin PF02223.17 EEQ39912.1 - 0.012 15.3 0.4 7.6 6.2 0.0 3.4 3 0 0 3 3 3 0 Thymidylate kinase AAA_33 PF13671.6 EEQ39912.1 - 0.015 15.5 0.3 4 7.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EEQ39912.1 - 0.04 13.9 0.1 13 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EEQ39912.1 - 0.044 13.0 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EEQ39912.1 - 0.045 13.5 0.2 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 EEQ39912.1 - 0.049 13.3 0.0 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E AAA_7 PF12775.7 EEQ39912.1 - 0.05 13.1 0.4 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 EEQ39912.1 - 0.052 13.8 0.5 15 5.8 0.1 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EEQ39912.1 - 0.057 13.4 1.2 0.78 9.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ39912.1 - 0.063 13.0 0.1 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Fer4_4 PF12800.7 EEQ39912.1 - 1.7 9.4 15.0 0.45 11.1 3.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 EEQ39912.1 - 9.2 6.9 11.6 0.38 11.3 1.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain HSA PF07529.13 EEQ39913.1 - 4e-12 46.3 3.2 4e-12 46.3 3.2 3.4 4 0 0 4 4 4 1 HSA Myb_DNA-bind_6 PF13921.6 EEQ39913.1 - 1.8e-08 34.5 1.9 3.1e-08 33.7 0.3 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EEQ39913.1 - 0.019 15.1 0.1 0.07 13.3 0.1 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain MerR-DNA-bind PF09278.11 EEQ39913.1 - 0.19 12.3 3.4 25 5.5 0.3 3.6 3 0 0 3 3 3 0 MerR, DNA binding Astro_capsid_p PF12226.8 EEQ39913.1 - 5.4 6.1 17.8 11 5.1 17.8 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sensor_TM1 PF13755.6 EEQ39914.1 - 0.0026 17.4 1.1 0.0064 16.2 1.1 1.6 1 0 0 1 1 1 1 Sensor N-terminal transmembrane domain NnrU PF07298.11 EEQ39914.1 - 0.058 12.9 3.8 0.11 12.0 3.8 1.4 1 0 0 1 1 1 0 NnrU protein SUN PF03856.13 EEQ39915.1 - 1.4e-85 286.7 14.9 1.6e-85 286.5 14.9 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Fungal_trans PF04082.18 EEQ39916.1 - 1.3e-12 47.3 0.0 2.5e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ39916.1 - 8.9e-07 28.9 11.3 1.6e-06 28.1 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_E4_34 PF04528.13 EEQ39916.1 - 0.036 13.9 0.1 0.075 12.9 0.1 1.5 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Fungal_trans PF04082.18 EEQ39917.1 - 2.6 7.0 7.2 10 5.1 0.4 3.2 3 0 0 3 3 3 0 Fungal specific transcription factor domain Septin PF00735.18 EEQ39918.1 - 1.2e-113 379.1 0.1 2e-113 378.3 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EEQ39918.1 - 2e-06 27.8 0.0 4.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ39918.1 - 1.4e-05 24.8 0.4 0.003 17.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ39918.1 - 4.3e-05 23.5 4.5 0.00053 19.9 0.1 3.2 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EEQ39918.1 - 0.00016 22.1 0.0 0.00047 20.6 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EEQ39918.1 - 0.0048 16.3 0.2 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family KAP_NTPase PF07693.14 EEQ39918.1 - 0.0059 15.9 0.0 0.014 14.7 0.0 1.7 1 1 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 EEQ39918.1 - 0.0059 16.9 0.5 0.018 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain DUF5082 PF16888.5 EEQ39918.1 - 0.007 16.6 1.1 0.016 15.5 1.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) AIG1 PF04548.16 EEQ39918.1 - 0.01 15.2 0.0 0.027 13.8 0.0 1.7 1 0 0 1 1 1 0 AIG1 family RNA_helicase PF00910.22 EEQ39918.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 EEQ39918.1 - 0.016 15.4 0.1 0.052 13.8 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF29 PF01724.16 EEQ39918.1 - 0.02 15.1 5.9 0.068 13.4 2.1 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF29 NACHT PF05729.12 EEQ39918.1 - 0.03 14.2 0.0 0.061 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Pox_A32 PF04665.12 EEQ39918.1 - 0.031 13.7 0.1 0.059 12.8 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein XhlA PF10779.9 EEQ39918.1 - 0.052 13.8 1.1 0.15 12.3 1.1 1.8 1 0 0 1 1 1 0 Haemolysin XhlA AAA_24 PF13479.6 EEQ39918.1 - 0.059 13.1 0.2 0.16 11.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EEQ39918.1 - 0.076 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 EEQ39918.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PRK PF00485.18 EEQ39918.1 - 0.15 11.8 0.6 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DDE_Tnp_IS240 PF13610.6 EEQ39918.1 - 0.36 11.1 5.2 0.62 10.3 3.1 2.2 2 0 0 2 2 2 0 DDE domain ABC_tran PF00005.27 EEQ39918.1 - 0.57 10.7 3.4 0.29 11.7 0.3 2.0 2 1 0 2 2 2 0 ABC transporter 14-3-3 PF00244.20 EEQ39919.1 - 1.2e-103 345.5 4.4 1.3e-103 345.3 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 EEQ39919.1 - 0.016 15.2 0.1 0.039 14.0 0.1 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Peptidase_M24 PF00557.24 EEQ39920.1 - 4.2e-05 23.3 0.0 8.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribonuclease_3 PF00636.26 EEQ39921.1 - 1.4e-22 80.3 0.1 4.2e-21 75.5 0.0 2.5 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EEQ39921.1 - 5.8e-20 71.7 1.1 1e-19 71.0 0.3 1.8 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.26 EEQ39921.1 - 4.7e-11 43.2 0.1 1.7e-05 25.4 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif DUF1757 PF08560.10 EEQ39921.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1757) Methyltransf_4 PF02390.17 EEQ39923.1 - 2.4e-30 105.3 1.1 2.4e-30 105.3 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.6 EEQ39923.1 - 0.0062 16.4 0.1 0.017 14.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EEQ39923.1 - 0.0087 15.6 0.0 0.016 14.8 0.0 1.4 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EEQ39923.1 - 0.0098 16.6 0.0 0.036 14.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ39923.1 - 0.033 14.9 0.1 0.091 13.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EEQ39923.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Reticulon PF02453.17 EEQ39925.1 - 1.9e-31 109.1 2.1 2.5e-31 108.7 2.1 1.2 1 0 0 1 1 1 1 Reticulon TAP35_44 PF07265.11 EEQ39925.1 - 0.14 12.2 1.6 0.26 11.3 1.6 1.5 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 VPS11_C PF12451.8 EEQ39927.1 - 6.7e-17 61.5 0.2 6.7e-17 61.5 0.2 3.4 4 0 0 4 4 4 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EEQ39927.1 - 1e-08 35.1 3.8 1e-08 35.1 3.8 2.4 3 0 0 3 3 2 1 Zinc-finger zf-ANAPC11 PF12861.7 EEQ39927.1 - 0.004 17.2 1.3 0.008 16.2 1.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Clathrin PF00637.20 EEQ39927.1 - 0.0051 16.7 9.1 0.0061 16.4 0.0 4.2 4 1 0 4 4 4 1 Region in Clathrin and VPS zf-RING_5 PF14634.6 EEQ39927.1 - 0.02 14.9 6.0 0.049 13.6 6.0 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-rbx1 PF12678.7 EEQ39927.1 - 0.035 14.4 4.2 0.09 13.1 4.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EEQ39927.1 - 0.13 12.2 7.9 0.44 10.5 7.9 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ39927.1 - 0.23 11.3 10.4 2.2 8.2 10.5 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ39927.1 - 0.34 11.0 5.1 1.1 9.3 5.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EEQ39927.1 - 0.36 11.2 11.9 0.03 14.6 6.6 2.1 2 0 0 2 2 2 0 Ring finger domain ADK_lid PF05191.14 EEQ39927.1 - 0.5 10.4 1.8 1.1 9.3 1.8 1.6 1 0 0 1 1 1 0 Adenylate kinase, active site lid zf-HC5HC2H PF13771.6 EEQ39927.1 - 1.5 9.1 6.1 0.4 11.0 2.2 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-Nse PF11789.8 EEQ39927.1 - 1.5 8.7 6.8 5.5 6.9 5.9 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Utp8 PF10395.9 EEQ39928.1 - 4.2e-196 653.5 34.1 4.8e-196 653.3 34.1 1.0 1 0 0 1 1 1 1 Utp8 family DUF1318 PF07027.12 EEQ39928.1 - 0.21 12.0 0.7 1.2 9.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) Complex1_LYR PF05347.15 EEQ39929.1 - 0.00033 20.6 0.1 0.0005 20.1 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) PTS_2-RNA PF01885.16 EEQ39930.1 - 1.8e-60 204.1 0.0 2.1e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PARP PF00644.20 EEQ39930.1 - 0.11 12.1 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain CAF20 PF17052.5 EEQ39932.1 - 4.2e-61 205.8 6.3 4.7e-61 205.6 6.3 1.0 1 0 0 1 1 1 1 Cap associated factor RRP7 PF12923.7 EEQ39932.1 - 0.011 15.9 6.7 0.029 14.5 5.9 2.1 1 1 1 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Tma16 PF11176.8 EEQ39933.1 - 2.9e-41 140.7 6.8 3.5e-41 140.5 6.8 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 FMP23 PF17315.2 EEQ39934.1 - 1.1e-07 32.1 24.0 0.0022 18.2 1.6 6.8 4 3 2 6 6 6 3 Found in mitochondrial proteome BILBO1_N PF18281.1 EEQ39934.1 - 1.4 9.4 4.7 1.5 9.3 0.1 3.5 4 0 0 4 4 4 0 BILBO1 N-terminal domain RGS PF00615.19 EEQ39935.1 - 6.4e-11 42.6 3.9 4e-08 33.5 3.9 2.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain NAT PF04768.13 EEQ39937.1 - 2.1e-52 177.2 0.3 9.9e-52 175.0 0.3 2.0 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EEQ39937.1 - 4.8e-30 104.5 0.0 1.1e-29 103.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EEQ39937.1 - 3e-29 102.3 0.1 3.9e-28 98.7 0.0 2.4 2 0 0 2 2 2 1 Amino acid kinase family DapB_N PF01113.20 EEQ39937.1 - 0.0011 19.1 0.0 0.0033 17.6 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Y_phosphatase2 PF03162.13 EEQ39938.1 - 3.2e-28 98.4 1.4 7.4e-27 93.9 1.4 2.3 1 1 0 1 1 1 1 Tyrosine phosphatase family RuvX PF03652.15 EEQ39938.1 - 0.12 12.7 0.2 0.77 10.1 0.0 2.0 2 0 0 2 2 2 0 Holliday junction resolvase Mso1_Sec1_bdg PF14475.6 EEQ39939.1 - 2.8e-17 62.0 0.2 4.9e-17 61.2 0.2 1.4 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Mso1_C PF14477.6 EEQ39939.1 - 3.1e-07 30.7 10.4 3.1e-07 30.7 10.4 3.2 2 1 2 4 4 4 1 Membrane-polarising domain of Mso1 DEAD PF00270.29 EEQ39940.1 - 1.2e-33 116.3 0.0 3.5e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ39940.1 - 1.8e-19 70.1 0.2 5.6e-19 68.5 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39940.1 - 1.2e-07 31.9 0.0 3.8e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sad1_UNC PF07738.13 EEQ39941.1 - 2.9e-31 108.2 0.4 1.2e-30 106.2 0.0 2.2 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal RAI1 PF08652.11 EEQ39942.1 - 3.4e-26 91.2 0.0 9.4e-26 89.8 0.0 1.8 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease HTH_23 PF13384.6 EEQ39943.1 - 3.4e-08 33.1 0.0 6.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EEQ39943.1 - 4.8e-08 33.0 0.0 8.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DDE_3 PF13358.6 EEQ39943.1 - 4.7e-06 26.4 0.0 2.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 EEQ39943.1 - 9.9e-06 25.8 0.1 2.1e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.6 EEQ39943.1 - 2.7e-05 24.1 0.0 6.5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix HTH_36 PF13730.6 EEQ39943.1 - 0.0026 17.7 0.0 0.0085 16.0 0.0 1.9 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_32 PF13565.6 EEQ39943.1 - 0.006 17.2 0.0 0.012 16.2 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_40 PF14493.6 EEQ39943.1 - 0.018 15.5 0.2 0.087 13.3 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Terminase_5 PF06056.12 EEQ39943.1 - 0.095 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Hexapep_2 PF14602.6 EEQ39943.1 - 0.1 12.4 0.0 8.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase HTH_17 PF12728.7 EEQ39943.1 - 0.18 12.0 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Catalase PF00199.19 EEQ39944.1 - 3.1e-191 635.5 0.3 4e-191 635.2 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EEQ39944.1 - 5.9e-14 52.0 0.3 8.4e-13 48.3 0.0 2.8 4 0 0 4 4 4 1 Catalase-related immune-responsive YpjP PF14005.6 EEQ39944.1 - 0.05 13.6 0.3 0.17 11.9 0.0 2.0 2 0 0 2 2 2 0 YpjP-like protein Torus PF16131.5 EEQ39946.1 - 2.6e-37 127.9 0.1 2.6e-37 127.9 0.1 2.0 2 1 1 3 3 3 1 Torus domain RRM_1 PF00076.22 EEQ39946.1 - 8.3e-10 38.3 0.0 1.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ39946.1 - 0.00012 22.0 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EEQ39946.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 EEQ39946.1 - 0.073 12.9 7.2 0.11 12.4 7.2 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger MMU163 PF17119.5 EEQ39946.1 - 0.082 12.0 2.6 0.12 11.5 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DUF4407 PF14362.6 EEQ39946.1 - 0.32 10.3 3.3 0.42 9.9 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCCH_2 PF14608.6 EEQ39946.1 - 0.44 11.1 5.4 0.86 10.2 5.4 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger PAPA-1 PF04795.12 EEQ39946.1 - 8.3 7.3 13.3 1.7 9.5 8.7 2.1 2 0 0 2 2 2 0 PAPA-1-like conserved region DEAD PF00270.29 EEQ39947.1 - 1.5e-43 148.6 0.2 1.2e-42 145.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ39947.1 - 5.3e-30 104.0 0.5 3.5e-29 101.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39947.1 - 2.9e-05 24.2 0.0 0.0011 19.1 0.0 2.7 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit Terpene_synth PF01397.21 EEQ39947.1 - 0.028 14.1 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain AAA_19 PF13245.6 EEQ39947.1 - 0.072 13.4 0.1 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 EEQ39948.1 - 1.9e-20 73.1 36.9 1.1e-16 60.7 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 EEQ39948.1 - 2.4e-12 46.9 8.9 2.4e-12 46.9 8.9 2.7 3 1 0 3 3 3 1 Nodulin-like PUCC PF03209.15 EEQ39948.1 - 0.046 12.7 9.6 0.0084 15.2 3.4 2.2 2 0 0 2 2 2 0 PUCC protein Phtf-FEM1B_bdg PF12129.8 EEQ39948.1 - 5.7 6.7 8.4 0.36 10.7 0.5 2.8 2 1 1 3 3 3 0 Male germ-cell putative homeodomain transcription factor DDE_3 PF13358.6 EEQ39949.1 - 1.5e-26 92.9 0.0 3.8e-18 65.6 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease rve PF00665.26 EEQ39949.1 - 0.09 13.0 0.0 0.22 11.7 0.0 1.6 2 0 0 2 2 2 0 Integrase core domain SLATT_5 PF18160.1 EEQ39949.1 - 0.096 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 NAC PF01849.18 EEQ39951.1 - 2.2e-16 59.6 0.9 3.7e-16 58.9 0.2 1.8 2 0 0 2 2 2 1 NAC domain DUF2330 PF10092.9 EEQ39951.1 - 0.033 13.3 0.0 0.036 13.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) GATase_6 PF13522.6 EEQ39952.1 - 1.7e-13 50.9 0.0 3.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EEQ39952.1 - 4.4e-10 39.5 0.0 7.6e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EEQ39952.1 - 2.1e-07 30.6 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EEQ39952.1 - 0.0073 15.2 0.0 0.019 13.9 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DEAD PF00270.29 EEQ39953.1 - 2.4e-42 144.7 0.0 3.6e-42 144.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ39953.1 - 8.7e-30 103.3 0.2 7.9e-28 97.0 0.2 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39953.1 - 0.0002 21.4 0.0 0.00035 20.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit GTP_EFTU PF00009.27 EEQ39954.1 - 2.8e-57 193.4 0.0 4.3e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EEQ39954.1 - 1.3e-14 54.0 0.0 6.5e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 EEQ39954.1 - 2.4e-12 46.8 0.0 6.6e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EEQ39954.1 - 1.3e-05 25.5 0.1 4.3e-05 23.8 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EEQ39954.1 - 0.014 15.1 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EEQ39954.1 - 0.054 13.6 0.0 0.24 11.5 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase RNase_T PF00929.24 EEQ39956.1 - 3.5e-07 30.9 0.0 7.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 EEQ39956.1 - 0.92 9.7 4.8 0.58 10.4 0.2 2.2 2 0 0 2 2 2 0 ElonginA binding-protein 1 DUF3591 PF12157.8 EEQ39958.1 - 6e-179 595.3 6.9 1.1e-178 594.5 6.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 EEQ39958.1 - 7.8e-08 32.0 0.7 2.3e-07 30.5 0.7 1.8 1 0 0 1 1 1 1 Zinc knuckle AA_permease PF00324.21 EEQ39959.1 - 4.2e-131 437.8 40.9 5.1e-131 437.6 40.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ39959.1 - 1.6e-34 119.5 41.0 1.9e-34 119.2 41.0 1.1 1 0 0 1 1 1 1 Amino acid permease Zn_clus PF00172.18 EEQ39961.1 - 5.9e-06 26.3 11.3 1e-05 25.5 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EEQ39961.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAP2_3 PF14378.6 EEQ39962.1 - 1.7e-18 67.0 20.0 5.2e-18 65.4 20.0 1.9 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.21 EEQ39962.1 - 1.9e-13 50.3 8.8 1.9e-13 50.3 8.8 2.7 3 0 0 3 3 3 1 PAP2 superfamily G_glu_transpept PF01019.21 EEQ39964.1 - 9.4e-132 440.4 0.0 1.1e-131 440.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CFEM PF05730.11 EEQ39965.1 - 6.1e-18 64.7 14.1 6.7e-09 35.7 2.1 2.8 3 0 0 3 3 3 2 CFEM domain NAD_binding_6 PF08030.12 EEQ39966.1 - 1.7e-07 31.5 0.0 2e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EEQ39967.1 - 1.1e-18 67.5 11.8 1.1e-18 67.5 11.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EEQ39967.1 - 2.2e-14 53.4 0.0 4.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain CFEM PF05730.11 EEQ39968.1 - 3.1e-13 49.6 9.1 6e-13 48.7 9.1 1.5 1 0 0 1 1 1 1 CFEM domain DUF913 PF06025.12 EEQ39968.1 - 0.019 13.9 2.4 0.022 13.7 2.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 EEQ39968.1 - 0.19 11.1 2.4 0.2 11.1 2.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF1180 PF06679.12 EEQ39968.1 - 0.94 9.9 7.2 1.4 9.3 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Apt1 PF10351.9 EEQ39968.1 - 7.1 5.4 11.7 8.8 5.1 11.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CFEM PF05730.11 EEQ39969.1 - 4.2e-14 52.4 10.8 7.7e-14 51.5 10.8 1.5 1 0 0 1 1 1 1 CFEM domain Plasmodium_Vir PF05795.11 EEQ39969.1 - 0.29 10.5 1.5 0.33 10.3 1.5 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Mitofilin PF09731.9 EEQ39969.1 - 5.4 5.7 13.2 7.5 5.3 13.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein p450 PF00067.22 EEQ39970.1 - 2.1e-66 224.6 0.1 2.7e-66 224.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CRAL_TRIO PF00650.20 EEQ39971.1 - 3.3e-37 127.7 0.0 5.2e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ39971.1 - 5.4e-06 26.5 0.1 2.2e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EEQ39971.1 - 5.1e-05 23.5 0.0 9.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1769 PF08588.10 EEQ39971.1 - 0.043 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) CN_hydrolase PF00795.22 EEQ39972.1 - 8.1e-44 149.9 0.0 9.5e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Autophagy_N PF03986.13 EEQ39973.1 - 0.0012 18.8 40.6 3.9 7.4 0.2 8.6 1 1 6 7 7 7 4 Autophagocytosis associated protein (Atg3), N-terminal domain KASH_CCD PF14662.6 EEQ39973.1 - 0.025 14.4 1.4 33 4.2 0.1 2.9 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4472 PF14739.6 EEQ39973.1 - 0.046 14.5 16.0 3.6 8.3 4.1 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4515 PF14988.6 EEQ39973.1 - 0.47 10.3 23.3 0.76 9.6 2.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) UCR_14kD PF02271.16 EEQ39973.1 - 8.6 6.4 33.8 40 4.3 1.9 6.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Oxidored_FMN PF00724.20 EEQ39975.1 - 1.2e-91 307.5 0.0 1.4e-91 307.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EEQ39975.1 - 0.071 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Pantoate_transf PF02548.15 EEQ39976.1 - 6.8e-104 346.8 0.1 8e-104 346.6 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EEQ39976.1 - 3.9e-09 36.3 0.3 1.7e-08 34.2 0.1 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Glyoxalase PF00903.25 EEQ39977.1 - 4.7e-32 110.9 1.0 8.7e-15 55.0 0.2 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EEQ39977.1 - 1.7e-06 28.2 0.1 0.052 13.8 0.0 3.4 1 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.6 EEQ39977.1 - 0.00074 19.6 0.1 0.13 12.3 0.0 3.0 3 0 0 3 3 3 1 CppA N-terminal Glyoxalase_2 PF12681.7 EEQ39977.1 - 0.0021 17.9 1.9 0.46 10.4 0.1 3.9 3 3 1 4 4 4 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EEQ39977.1 - 0.0071 17.1 0.0 6.9 7.5 0.0 2.7 2 2 0 2 2 2 2 Glyoxalase-like domain PRT_C PF08372.10 EEQ39977.1 - 0.043 13.6 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal PP2C PF00481.21 EEQ39978.1 - 6.9e-37 127.5 0.0 9.9e-23 81.1 0.0 3.0 2 1 1 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.6 EEQ39978.1 - 3.2e-06 26.9 0.0 9.1e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Ribosomal_S19 PF00203.21 EEQ39979.1 - 1.9e-26 91.7 0.0 2.4e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 AF-4 PF05110.13 EEQ39980.1 - 0.00058 18.1 22.7 0.00063 18.0 22.7 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein NESP55 PF06390.12 EEQ39980.1 - 0.0012 18.5 8.7 0.0012 18.5 8.7 1.1 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 EEQ39980.1 - 0.0025 17.8 8.8 0.0028 17.6 8.8 1.1 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) DUF4834 PF16118.5 EEQ39980.1 - 0.56 11.2 7.6 0.63 11.0 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Paf1 PF03985.13 EEQ39980.1 - 0.84 8.6 16.5 0.88 8.5 16.5 1.0 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 EEQ39980.1 - 0.86 7.7 17.0 0.89 7.7 17.0 1.0 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 EEQ39980.1 - 1 9.1 13.2 1.1 9.0 13.2 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 EEQ39980.1 - 1.3 8.1 11.6 1.4 8.0 11.6 1.0 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF4820 PF16091.5 EEQ39980.1 - 1.6 8.1 8.7 1.8 7.9 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) AIF_C PF14721.6 EEQ39980.1 - 1.9 8.9 6.7 2.1 8.7 6.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term RR_TM4-6 PF06459.12 EEQ39980.1 - 2.1 8.1 12.6 2.2 8.1 12.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EEQ39980.1 - 2.4 6.3 15.7 2.5 6.3 15.7 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EEQ39980.1 - 2.5 7.7 12.2 3.4 7.3 12.2 1.2 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 EEQ39980.1 - 3 5.8 21.6 3.4 5.7 21.6 1.0 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 EEQ39980.1 - 3.6 6.8 11.6 3.8 6.7 11.6 1.0 1 0 0 1 1 1 0 NOA36 protein TEX19 PF15553.6 EEQ39980.1 - 3.6 7.5 7.3 4.4 7.2 7.3 1.2 1 0 0 1 1 1 0 Testis-expressed protein 19 Sec62 PF03839.16 EEQ39980.1 - 3.8 7.0 7.8 4.1 6.8 7.8 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RPN2_C PF18004.1 EEQ39980.1 - 4.2 7.3 14.5 4.5 7.2 14.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 EEQ39980.1 - 4.7 5.9 11.1 4.8 5.8 11.1 1.0 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 EEQ39980.1 - 4.8 7.6 10.0 4.9 7.6 10.0 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DDHD PF02862.17 EEQ39980.1 - 4.9 7.3 9.1 5.2 7.2 9.1 1.1 1 0 0 1 1 1 0 DDHD domain MAP17 PF15807.5 EEQ39980.1 - 4.9 7.4 9.5 5.2 7.3 9.5 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NPR3 PF03666.13 EEQ39980.1 - 5 5.8 13.5 5.5 5.7 13.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 NARP1 PF12569.8 EEQ39980.1 - 5.3 5.8 10.5 5.8 5.7 10.5 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Coilin_N PF15862.5 EEQ39980.1 - 6.5 6.6 14.4 7.2 6.4 14.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus RP-C_C PF11800.8 EEQ39980.1 - 6.8 6.7 10.4 7.5 6.6 10.4 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region CSG2 PF16965.5 EEQ39980.1 - 7.4 5.4 6.0 7.9 5.3 6.0 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator Smg8_Smg9 PF10220.9 EEQ39980.1 - 8.5 4.5 9.7 9.4 4.4 9.7 1.0 1 0 0 1 1 1 0 Smg8_Smg9 Pes-10 PF07149.11 EEQ39980.1 - 8.8 5.3 12.0 9.9 5.1 12.0 1.0 1 0 0 1 1 1 0 Pes-10 TRAP_alpha PF03896.16 EEQ39980.1 - 9 5.4 9.1 9.9 5.3 9.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DEAD PF00270.29 EEQ39981.1 - 2.9e-38 131.4 0.2 9.5e-38 129.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ39981.1 - 2.8e-14 53.4 0.3 1.2e-13 51.4 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ39981.1 - 7.8e-09 35.8 0.6 1.1e-07 32.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EEQ39981.1 - 0.02 15.2 2.1 0.29 11.4 0.9 3.0 2 1 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 EEQ39981.1 - 0.04 13.9 0.0 0.096 12.7 0.0 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain CMS1 PF14617.6 EEQ39981.1 - 0.066 12.5 1.1 0.21 10.9 0.1 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4535 PF15054.6 EEQ39982.1 - 0.039 13.7 0.2 0.15 11.8 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) RT_RNaseH_2 PF17919.1 EEQ39983.1 - 5.9e-35 119.3 0.4 1.4e-34 118.1 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EEQ39983.1 - 2.8e-33 114.3 0.1 6.1e-33 113.3 0.1 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EEQ39983.1 - 3.2e-31 108.6 0.5 8e-31 107.3 0.5 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 EEQ39983.1 - 2e-16 59.8 0.6 4.9e-16 58.6 0.6 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EEQ39983.1 - 2.9e-14 53.3 0.0 8.2e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease_2 PF13650.6 EEQ39983.1 - 0.0042 17.7 0.0 0.0097 16.5 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease Methyltransf_15 PF09445.10 EEQ39984.1 - 1.2e-51 174.6 0.0 1.6e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 EEQ39984.1 - 9.6e-09 35.8 0.0 1.7e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ39984.1 - 6.8e-08 32.5 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ39984.1 - 1.5e-06 28.1 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ39984.1 - 3.8e-05 24.2 0.0 8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EEQ39984.1 - 4.8e-05 23.0 0.1 0.00011 21.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 EEQ39984.1 - 0.00026 20.8 0.0 0.00054 19.7 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.18 EEQ39984.1 - 0.00049 19.5 0.0 0.00072 19.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 EEQ39984.1 - 0.00096 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F N6_Mtase PF02384.16 EEQ39984.1 - 0.0018 17.6 0.0 0.0034 16.7 0.0 1.4 1 1 0 1 1 1 1 N-6 DNA Methylase PCMT PF01135.19 EEQ39984.1 - 0.013 15.3 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 EEQ39984.1 - 0.016 16.0 0.0 0.026 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EEQ39984.1 - 0.04 13.3 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TehB PF03848.14 EEQ39984.1 - 0.077 12.4 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CMAS PF02353.20 EEQ39984.1 - 0.16 11.2 0.3 0.35 10.1 0.1 1.6 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase MCM PF00493.23 EEQ39985.1 - 2.2e-96 321.3 0.4 3.4e-96 320.7 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ39985.1 - 1.7e-30 105.5 0.0 3.1e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ39985.1 - 1.8e-23 82.8 3.3 7.3e-23 80.8 3.3 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ39985.1 - 1.4e-12 48.1 0.0 4e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ39985.1 - 1.3e-07 31.3 0.0 1.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EEQ39985.1 - 0.0025 17.6 0.0 0.006 16.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ39985.1 - 0.0056 16.4 0.0 0.02 14.6 0.0 1.9 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EEQ39985.1 - 0.0093 16.0 0.0 0.29 11.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) CBF PF03914.17 EEQ39986.1 - 1.8e-30 106.2 0.5 1.8e-30 106.2 0.5 2.1 2 1 0 2 2 2 1 CBF/Mak21 family ApoA-II PF04711.13 EEQ39986.1 - 0.094 12.9 1.4 0.92 9.7 0.2 3.0 4 0 0 4 4 4 0 Apolipoprotein A-II (ApoA-II) Ribosomal_L21e PF01157.18 EEQ39987.1 - 4.2e-40 135.7 5.9 4.4e-40 135.6 4.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 EEQ39987.1 - 0.00036 20.2 0.0 0.00044 19.9 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 CwfJ_C_1 PF04677.15 EEQ39988.1 - 9.8e-29 99.7 0.1 2.2e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EEQ39988.1 - 4.4e-13 49.9 0.2 2.2e-12 47.7 0.0 2.3 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 SET PF00856.28 EEQ39989.1 - 1.9e-15 57.7 0.0 7.3e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 SET domain AA_permease PF00324.21 EEQ39990.1 - 4.1e-73 246.6 27.5 5.1e-73 246.3 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ39990.1 - 5.7e-21 74.8 28.9 6.9e-21 74.6 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ39991.1 - 1.1e-113 380.4 29.5 1.4e-113 380.1 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ39991.1 - 1.4e-35 122.9 28.9 1.7e-35 122.7 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ39992.1 - 1.5e-91 307.4 25.0 1.9e-91 307.1 25.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ39992.1 - 2.4e-23 82.7 24.3 3.8e-23 82.0 24.3 1.3 1 0 0 1 1 1 1 Amino acid permease GCR1_C PF12550.8 EEQ39993.1 - 3.6e-21 75.3 0.6 7.7e-21 74.2 0.6 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Neur_chan_memb PF02932.16 EEQ39993.1 - 0.47 10.5 27.4 0.67 10.0 21.4 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Borrelia_P83 PF05262.11 EEQ39993.1 - 3.2 6.1 26.3 4.1 5.8 26.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SPX PF03105.19 EEQ39993.1 - 10 5.9 37.0 12 5.7 27.7 2.3 2 0 0 2 2 2 0 SPX domain HSP70 PF00012.20 EEQ39994.1 - 3.4e-265 880.9 14.9 3.9e-265 880.7 14.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ39994.1 - 2.8e-15 56.0 6.6 9.5e-14 50.9 3.6 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EEQ39994.1 - 0.00011 22.1 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF615 PF04751.14 EEQ39994.1 - 0.002 18.1 3.4 0.0055 16.7 3.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF615) FtsA PF14450.6 EEQ39994.1 - 0.012 16.0 10.2 0.1 13.0 1.3 4.1 3 1 0 3 3 3 0 Cell division protein FtsA MRP-S27 PF10037.9 EEQ39994.1 - 0.098 11.5 8.0 0.18 10.6 8.0 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 HXXSHH PF07586.11 EEQ39994.1 - 1.9 8.0 5.5 3.2 7.2 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Asp PF00026.23 EEQ39996.1 - 1.7e-101 339.8 0.0 2.4e-101 339.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ39996.1 - 6.3e-14 52.6 0.3 2.9e-11 43.9 0.3 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEQ39996.1 - 6.9e-05 23.4 0.0 0.076 13.7 0.0 2.5 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 EEQ39996.1 - 0.00053 20.5 0.0 0.079 13.5 0.0 2.5 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EEQ39996.1 - 0.0063 16.3 0.0 0.034 13.9 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Cellulase PF00150.18 EEQ39997.1 - 2.1e-12 47.1 0.8 2.1e-12 47.1 0.8 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) LigD_N PF13298.6 EEQ39997.1 - 0.0092 16.3 0.5 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 DNA polymerase Ligase (LigD) DEAD PF00270.29 EEQ39998.1 - 3.3e-21 75.8 0.0 6.6e-20 71.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ39998.1 - 2.5e-16 60.0 0.0 4.2e-15 56.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EEQ39998.1 - 6.1e-14 52.6 2.3 3.3e-13 50.2 0.9 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Adaptin_N PF01602.20 EEQ39999.1 - 1.3e-84 284.7 2.2 1.8e-84 284.2 2.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEQ39999.1 - 6.9e-42 143.2 0.1 3.3e-37 128.0 0.1 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ39999.1 - 3.4e-14 53.0 0.8 0.00047 20.5 0.2 5.8 4 1 1 6 6 6 3 HEAT repeats Arm PF00514.23 EEQ39999.1 - 4.2e-07 29.8 4.8 0.043 13.9 0.1 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EEQ39999.1 - 0.00011 22.1 9.9 0.087 13.1 0.0 5.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EEQ39999.1 - 0.00026 21.4 3.6 3.9 8.1 0.1 5.0 5 0 0 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 EEQ39999.1 - 0.0007 19.7 0.4 12 6.1 0.1 3.6 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 EEQ39999.1 - 0.085 13.3 0.2 0.78 10.2 0.1 2.6 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Nipped-B_C PF12830.7 EEQ39999.1 - 0.097 12.6 1.5 2.3 8.1 0.0 3.1 4 0 0 4 4 4 0 Sister chromatid cohesion C-terminus Memo PF01875.17 EEQ40000.1 - 2.1e-71 240.3 0.0 2.4e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Pkinase PF00069.25 EEQ40001.1 - 1.3e-48 165.7 0.0 1.6e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40001.1 - 1e-18 67.6 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ40001.1 - 0.013 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EEQ40001.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ40001.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EEQ40001.1 - 0.18 11.1 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EIF_2_alpha PF07541.12 EEQ40002.1 - 2.3e-40 137.3 0.1 4.8e-40 136.3 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EEQ40002.1 - 3.1e-15 56.3 1.5 5.7e-15 55.4 1.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain LZ3wCH PF18517.1 EEQ40002.1 - 0.09 12.9 0.0 0.33 11.1 0.0 2.1 1 0 0 1 1 1 0 Leucine zipper with capping helix domain LRR_8 PF13855.6 EEQ40003.1 - 2.9e-21 75.0 8.2 1.8e-06 27.6 0.2 5.9 5 1 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EEQ40003.1 - 6.3e-20 70.9 16.1 0.0001 22.6 1.1 7.9 3 2 8 11 11 11 9 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EEQ40003.1 - 2.1e-09 36.7 0.6 1 9.6 0.0 8.0 10 0 0 10 10 10 2 Leucine Rich repeat FNIP PF05725.12 EEQ40003.1 - 2.7e-07 30.6 15.0 0.022 14.9 0.1 6.1 5 2 3 8 8 8 4 FNIP Repeat LRR_1 PF00560.33 EEQ40003.1 - 0.0019 18.5 21.6 16 6.5 0.2 8.8 8 2 0 8 8 8 1 Leucine Rich Repeat MFS_1 PF07690.16 EEQ40004.1 - 6.6e-18 64.7 51.6 6.6e-18 64.7 51.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EEQ40004.1 - 0.06 11.9 46.6 0.018 13.6 8.5 2.6 1 1 2 3 3 3 0 MFS/sugar transport protein Arginase PF00491.21 EEQ40005.1 - 4.7e-86 288.8 0.1 6.9e-86 288.2 0.1 1.2 1 0 0 1 1 1 1 Arginase family Choline_transpo PF04515.12 EEQ40006.1 - 2e-78 263.8 16.8 2e-78 263.8 16.8 2.7 3 0 0 3 3 3 1 Plasma-membrane choline transporter Metallophos_2 PF12850.7 EEQ40007.1 - 8.5e-11 42.3 0.0 1e-10 42.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NOT2_3_5 PF04153.18 EEQ40008.1 - 1.6e-32 112.4 0.9 2.1e-32 112.0 0.9 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_18 PF13238.6 EEQ40009.1 - 3.7e-28 98.7 0.8 4.7e-28 98.3 0.1 1.5 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.6 EEQ40009.1 - 2e-06 28.3 0.1 6.1e-06 26.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EEQ40009.1 - 2.7e-06 27.6 0.0 0.0013 18.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 EEQ40009.1 - 1.9e-05 25.1 0.0 4.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ40009.1 - 0.0014 19.1 0.0 0.0018 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 EEQ40009.1 - 0.0025 17.7 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein ADK PF00406.22 EEQ40009.1 - 0.003 17.7 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 EEQ40009.1 - 0.0034 17.6 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 EEQ40009.1 - 0.0045 16.9 0.1 0.3 10.9 0.0 2.2 1 1 1 2 2 2 1 Deoxynucleoside kinase AAA_22 PF13401.6 EEQ40009.1 - 0.0047 17.2 0.0 0.0078 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EEQ40009.1 - 0.0062 16.2 0.0 0.78 9.4 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase RNA_helicase PF00910.22 EEQ40009.1 - 0.0081 16.5 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase KTI12 PF08433.10 EEQ40009.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 T2SSE PF00437.20 EEQ40009.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 EEQ40009.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Sigma54_activ_2 PF14532.6 EEQ40009.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EEQ40009.1 - 0.027 13.8 0.0 0.049 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.14 EEQ40009.1 - 0.032 14.2 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EEQ40009.1 - 0.032 14.0 0.0 0.085 12.6 0.0 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 EEQ40009.1 - 0.04 13.4 0.0 0.055 13.0 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EEQ40009.1 - 0.04 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EEQ40009.1 - 0.04 14.3 0.1 0.077 13.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EEQ40009.1 - 0.042 13.6 0.6 0.085 12.6 0.1 1.7 2 1 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 EEQ40009.1 - 0.073 12.6 0.0 8.7 5.8 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Sigma54_activat PF00158.26 EEQ40009.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.9 EEQ40009.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 EEQ40009.1 - 0.082 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 NTPase ATPase_2 PF01637.18 EEQ40009.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea CobU PF02283.16 EEQ40009.1 - 0.12 12.0 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase MeaB PF03308.16 EEQ40009.1 - 0.13 11.2 0.2 0.26 10.2 0.1 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 EEQ40009.1 - 0.14 11.5 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Glutaredoxin PF00462.24 EEQ40009.1 - 0.15 12.3 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin AAA_14 PF13173.6 EEQ40009.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EEQ40009.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Heme_oxygenase PF01126.20 EEQ40010.1 - 2.3e-23 83.1 1.7 4.3e-23 82.2 1.7 1.5 1 1 0 1 1 1 1 Heme oxygenase AA_permease PF00324.21 EEQ40011.1 - 3.7e-122 408.4 36.6 4.2e-122 408.2 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ40011.1 - 1e-37 130.0 39.5 1.2e-37 129.7 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease PRELI PF04707.14 EEQ40013.1 - 1.6e-40 138.5 0.1 1.9e-40 138.2 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family RPN2_C PF18004.1 EEQ40014.1 - 0.2 11.6 6.8 0.31 10.9 6.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Prefoldin_2 PF01920.20 EEQ40015.1 - 1.4e-20 73.2 8.1 1.6e-20 73.0 8.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit FliJ PF02050.16 EEQ40015.1 - 0.00034 20.8 3.8 0.04 14.1 0.2 2.0 2 0 0 2 2 2 2 Flagellar FliJ protein DUF1192 PF06698.11 EEQ40015.1 - 0.02 14.9 2.7 0.022 14.8 0.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) STAT_alpha PF01017.20 EEQ40015.1 - 0.028 14.3 3.2 0.039 13.8 3.2 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF1104 PF06518.11 EEQ40015.1 - 0.042 14.2 2.9 0.067 13.6 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) TACC_C PF05010.14 EEQ40015.1 - 0.049 13.4 1.4 0.049 13.4 1.4 2.0 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal ADIP PF11559.8 EEQ40015.1 - 0.067 13.3 4.4 1.2 9.2 0.2 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 EEQ40015.1 - 0.081 13.1 4.8 0.47 10.7 0.5 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PHM7_cyt PF14703.6 EEQ40015.1 - 0.13 12.5 3.2 0.21 11.8 3.2 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF1664 PF07889.12 EEQ40015.1 - 0.14 12.2 2.4 0.32 11.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF5104 PF17117.5 EEQ40015.1 - 0.21 12.1 3.9 1.8 9.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5104) Spc24 PF08286.11 EEQ40015.1 - 0.25 11.6 6.8 0.61 10.4 1.0 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Prefoldin PF02996.17 EEQ40015.1 - 0.43 10.5 5.8 1.9 8.4 5.8 1.8 1 1 0 1 1 1 0 Prefoldin subunit FlaC_arch PF05377.11 EEQ40015.1 - 2.3 8.7 7.4 8.9 6.8 0.3 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MRPL52 PF18699.1 EEQ40015.1 - 2.5 8.3 6.9 0.44 10.8 2.2 1.9 2 0 0 2 2 2 0 Mitoribosomal protein mL52 COQ9 PF08511.11 EEQ40016.1 - 3.4e-26 90.8 0.4 6.3e-26 89.9 0.4 1.4 1 0 0 1 1 1 1 COQ9 POC1 PF10450.9 EEQ40017.1 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 POC1 chaperone Mpv17_PMP22 PF04117.12 EEQ40018.1 - 2e-21 76.0 5.1 3e-21 75.4 3.5 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family NADH_u_ox_C PF12853.7 EEQ40019.1 - 3.9e-49 164.6 1.4 6.6e-49 163.8 1.4 1.4 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.9 EEQ40019.1 - 1.1e-27 96.5 0.1 1.6e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF3943 PF13084.6 EEQ40019.1 - 0.2 11.5 0.3 26 4.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) CLASP_N PF12348.8 EEQ40020.1 - 1.8e-10 40.8 2.8 3e-09 36.8 0.1 3.1 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 EEQ40020.1 - 5.5e-05 23.1 0.0 1.6 9.2 0.0 5.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EEQ40020.1 - 0.00041 20.7 0.6 0.34 11.3 0.0 4.4 2 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.7 EEQ40020.1 - 0.056 13.5 1.1 0.22 11.6 0.0 2.5 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF4047 PF13256.6 EEQ40020.1 - 2.5 8.3 12.7 49 4.1 0.0 4.5 4 1 0 4 4 4 0 Domain of unknown function (DUF4047) ETF PF01012.21 EEQ40021.1 - 1.9e-41 141.9 0.4 2.3e-41 141.7 0.4 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain PRK PF00485.18 EEQ40023.1 - 1.2e-07 31.7 0.0 4.4e-07 29.8 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EEQ40023.1 - 3.6e-05 24.2 0.0 0.00089 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 EEQ40023.1 - 7.7e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 EEQ40023.1 - 0.00026 21.0 0.0 0.00049 20.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 EEQ40023.1 - 0.00039 19.8 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_33 PF13671.6 EEQ40023.1 - 0.0011 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ40023.1 - 0.008 16.7 0.1 0.027 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EEQ40023.1 - 0.011 15.8 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EEQ40023.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MobB PF03205.14 EEQ40023.1 - 0.016 15.1 0.0 0.64 9.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Torsin PF06309.11 EEQ40023.1 - 0.036 14.2 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA PF00004.29 EEQ40023.1 - 0.051 14.0 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 EEQ40023.1 - 0.054 13.1 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain APS_kinase PF01583.20 EEQ40023.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 EEQ40023.1 - 0.082 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EEQ40023.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain PIF1 PF05970.14 EEQ40023.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_30 PF13604.6 EEQ40023.1 - 0.13 12.0 0.1 3 7.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain PhoH PF02562.16 EEQ40023.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 EEQ40023.1 - 0.22 11.4 0.0 0.4 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea LolB PF03550.14 EEQ40024.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein LolB Proteasome PF00227.26 EEQ40025.1 - 1.3e-45 155.2 0.5 1.5e-45 155.0 0.5 1.0 1 0 0 1 1 1 1 Proteasome subunit Pro_isomerase PF00160.21 EEQ40026.1 - 2.6e-40 138.3 0.1 3.2e-40 138.0 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EEQ40027.1 - 1.1e-15 57.2 0.0 1.4e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ40027.1 - 0.0015 18.1 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EEQ40027.1 - 0.047 13.8 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Limkain b1 Ribophorin_I PF04597.14 EEQ40028.1 - 9.6e-108 361.2 0.2 1.1e-107 361.0 0.2 1.0 1 0 0 1 1 1 1 Ribophorin I Dynamin_M PF01031.20 EEQ40029.1 - 1.3e-106 356.0 0.0 2.9e-106 354.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EEQ40029.1 - 1.3e-53 181.5 0.2 3.8e-53 180.0 0.0 1.9 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EEQ40029.1 - 1.7e-29 101.8 2.7 4.1e-29 100.6 2.7 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EEQ40029.1 - 5.7e-05 23.2 0.0 0.55 10.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ40029.1 - 0.0044 16.5 0.5 0.82 9.2 0.1 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B SUIM_assoc PF16619.5 EEQ40029.1 - 0.11 12.6 0.6 0.69 10.0 0.6 2.4 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-H2C2_5 PF13909.6 EEQ40029.1 - 0.18 11.6 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain XhlA PF10779.9 EEQ40029.1 - 1.3 9.3 3.7 14 6.0 1.5 2.7 2 0 0 2 2 2 0 Haemolysin XhlA Saw1 PF11561.8 EEQ40030.1 - 2.6e-10 40.2 0.9 1.3e-09 38.0 0.8 2.1 1 1 0 1 1 1 1 Single strand annealing-weakened 1 GlcNAc PF11397.8 EEQ40031.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase (GlcNAc) FAS_I_H PF18314.1 EEQ40032.1 - 1.2e-74 250.3 0.3 1.2e-74 250.3 0.3 2.1 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EEQ40032.1 - 4.5e-73 244.9 0.0 1.1e-72 243.6 0.0 1.8 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EEQ40032.1 - 4.2e-20 72.4 0.1 1e-19 71.1 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EEQ40032.1 - 6.7e-16 58.4 0.0 1.7e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EEQ40032.1 - 3.1e-12 46.5 0.0 1.2e-11 44.7 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EEQ40032.1 - 5.2e-07 29.3 0.0 1.8e-06 27.6 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ40032.1 - 0.0024 17.8 0.0 0.0097 15.8 0.0 2.1 1 0 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 EEQ40032.1 - 0.047 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding F420_oxidored PF03807.17 EEQ40032.1 - 0.05 14.2 0.1 0.23 12.1 0.1 2.2 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Tox-ODYAM1 PF15642.6 EEQ40032.1 - 0.12 11.3 2.3 0.27 10.2 2.3 1.5 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus Spc7 PF08317.11 EEQ40032.1 - 9.3 5.0 11.7 0.12 11.2 3.8 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Sec7 PF01369.20 EEQ40033.1 - 5e-70 234.9 0.0 1.4e-69 233.5 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EEQ40033.1 - 7.3e-43 146.2 3.6 7.3e-43 146.2 3.6 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EEQ40033.1 - 6e-32 109.3 6.4 1.3e-31 108.3 0.3 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) DCB PF16213.5 EEQ40033.1 - 1e-07 31.8 0.1 9.8e-07 28.6 0.0 2.4 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Stb3 PF10330.9 EEQ40034.1 - 1.5e-29 101.8 0.3 3.5e-29 100.7 0.0 1.6 2 0 0 2 2 2 1 Putative Sin3 binding protein DUF2726 PF10881.8 EEQ40034.1 - 0.12 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) MCM PF00493.23 EEQ40035.1 - 1.9e-101 337.8 0.0 3.5e-101 337.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EEQ40035.1 - 2.4e-32 111.4 0.3 4.6e-32 110.5 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ40035.1 - 3.9e-23 81.7 0.1 1.3e-22 80.0 0.1 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ40035.1 - 1.2e-20 74.0 0.6 3.8e-20 72.4 0.6 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ40035.1 - 4.8e-08 32.6 0.0 3.2e-05 23.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ40035.1 - 2.2e-06 27.7 0.0 1e-05 25.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEQ40035.1 - 0.03 14.2 0.0 0.092 12.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ40035.1 - 0.13 12.0 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-UDP PF14569.6 EEQ40035.1 - 0.14 12.3 0.7 0.36 11.0 0.7 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger AAA_16 PF13191.6 EEQ40035.1 - 0.58 10.5 2.0 2.4 8.5 0.0 2.8 3 2 0 4 4 4 0 AAA ATPase domain DUF202 PF02656.15 EEQ40036.1 - 9.6e-17 61.2 0.4 9.6e-17 61.2 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Tho1_MOS11_C PF18592.1 EEQ40037.1 - 2.8e-23 81.5 1.9 2.8e-23 81.5 1.9 1.8 2 0 0 2 2 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 EEQ40037.1 - 3.6e-13 48.9 1.1 5.9e-13 48.2 0.1 1.9 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 EEQ40037.1 - 0.0018 17.9 0.2 0.0018 17.9 0.2 2.0 2 0 0 2 2 2 1 HeH/LEM domain INO80_Ies4 PF08193.11 EEQ40037.1 - 0.055 13.5 10.7 0.071 13.1 10.7 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 DUF2868 PF11067.8 EEQ40037.1 - 0.066 12.7 4.9 0.091 12.3 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) Trypan_PARP PF05887.11 EEQ40037.1 - 0.12 12.3 17.1 0.18 11.8 17.1 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4518 PF15008.6 EEQ40037.1 - 0.34 10.1 2.4 0.48 9.6 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Rxt3 PF08642.10 EEQ40037.1 - 0.41 11.4 2.8 0.79 10.5 2.8 1.6 1 1 0 1 1 1 0 Histone deacetylation protein Rxt3 RP-C_C PF11800.8 EEQ40037.1 - 0.91 9.6 7.9 1.1 9.3 7.9 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region UPF0560 PF10577.9 EEQ40037.1 - 1.3 7.4 5.6 1.5 7.2 5.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Presenilin PF01080.17 EEQ40037.1 - 1.5 7.5 5.5 1.4 7.6 5.5 1.1 1 0 0 1 1 1 0 Presenilin DUF3408 PF11888.8 EEQ40037.1 - 1.8 8.7 10.4 2.7 8.1 10.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Use1 PF09753.9 EEQ40037.1 - 2.5 7.8 8.8 3 7.5 8.8 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 Spore_coat_CotO PF14153.6 EEQ40037.1 - 4.7 7.1 17.7 6 6.8 17.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.14 EEQ40037.1 - 4.9 5.3 9.8 5.7 5.1 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 EEQ40037.1 - 6 5.7 6.6 7 5.5 6.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FGF-BP1 PF06473.12 EEQ40037.1 - 7.5 6.3 11.1 9.8 5.9 11.1 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Peptidase_M1 PF01433.20 EEQ40038.1 - 1.7e-75 253.4 1.0 2.8e-75 252.6 1.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EEQ40038.1 - 4.5e-64 217.0 0.2 8.5e-64 216.1 0.2 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EEQ40038.1 - 1.1e-49 169.1 0.0 2.4e-49 168.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF45 PF01863.17 EEQ40038.1 - 0.097 12.7 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF45 Asn_synthase PF00733.21 EEQ40039.1 - 3.8e-94 316.3 0.2 3.6e-52 178.2 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EEQ40039.1 - 2.9e-35 120.9 0.0 4.9e-35 120.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EEQ40039.1 - 7.5e-28 97.4 0.0 1.9e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EEQ40039.1 - 6.1e-07 29.1 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EEQ40039.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase CSN8_PSD8_EIF3K PF10075.9 EEQ40040.1 - 3.6e-13 49.7 0.2 8.3e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EEQ40040.1 - 0.002 17.6 2.2 0.0029 17.0 2.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family VPS28 PF03997.12 EEQ40041.1 - 1.2e-60 204.4 0.1 1.5e-60 204.2 0.1 1.1 1 0 0 1 1 1 1 VPS28 protein GCP_C_terminal PF04130.13 EEQ40041.1 - 0.016 14.6 0.9 2.2 7.7 0.1 2.1 1 1 1 2 2 2 0 Gamma tubulin complex component C-terminal Vps23_core PF09454.10 EEQ40041.1 - 0.16 12.0 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Vps23 core domain Arrestin_C PF02752.22 EEQ40042.1 - 0.026 15.0 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Steroid_dh PF02544.16 EEQ40044.1 - 2e-08 34.3 7.0 2e-08 34.3 7.0 1.6 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Transp_cyt_pur PF02133.15 EEQ40045.1 - 1.5e-63 215.1 38.0 2e-63 214.7 38.0 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Syntaxin PF00804.25 EEQ40047.1 - 4.6e-19 68.9 19.7 4.6e-19 68.9 19.7 1.8 1 1 1 2 2 2 1 Syntaxin SNARE PF05739.19 EEQ40047.1 - 6.1e-11 42.1 1.5 6.1e-11 42.1 1.5 2.4 3 0 0 3 3 3 1 SNARE domain DUF745 PF05335.13 EEQ40047.1 - 0.0088 15.8 6.8 0.0088 15.8 6.8 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF745) DUF3671 PF12420.8 EEQ40047.1 - 0.021 14.9 0.1 0.041 14.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function Pox_EPC_I2-L1 PF12575.8 EEQ40047.1 - 0.026 14.8 1.9 0.083 13.1 0.1 2.7 4 0 0 4 4 4 0 Poxvirus entry protein complex L1 and I2 LMBR1 PF04791.16 EEQ40047.1 - 0.03 13.2 5.3 0.043 12.7 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PBP1_TM PF14812.6 EEQ40047.1 - 0.099 13.0 0.0 0.099 13.0 0.0 2.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1659 PF07872.11 EEQ40047.1 - 0.11 12.2 0.6 0.27 10.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) Syntaxin_2 PF14523.6 EEQ40047.1 - 0.18 12.2 20.5 0.055 13.8 8.5 2.8 2 1 1 3 3 3 0 Syntaxin-like protein YflT PF11181.8 EEQ40047.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.4 2 1 1 4 4 4 0 Heat induced stress protein YflT T2SSF PF00482.23 EEQ40047.1 - 0.52 10.3 3.0 0.31 11.0 0.3 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F ACCA PF03255.14 EEQ40047.1 - 0.55 10.1 11.8 0.26 11.2 0.8 2.5 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF2203 PF09969.9 EEQ40047.1 - 1.7 9.4 15.8 2.6 8.8 3.6 3.1 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) Tetraspanin PF00335.20 EEQ40047.1 - 2.5 7.8 4.3 0.75 9.5 1.2 1.6 2 0 0 2 2 2 0 Tetraspanin family T6PP_N PF18572.1 EEQ40047.1 - 2.9 7.8 8.3 0.21 11.5 1.1 2.6 3 1 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain Cauli_AT PF03233.13 EEQ40047.1 - 7.3 6.5 7.3 1.4 8.9 1.2 2.4 1 1 0 2 2 2 0 Aphid transmission protein IPK PF03770.16 EEQ40048.1 - 3.2e-51 174.0 0.0 4e-51 173.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase FAM176 PF14851.6 EEQ40048.1 - 0.33 10.6 3.9 0.55 9.9 3.9 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 EEQ40048.1 - 0.48 8.5 8.1 0.58 8.2 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi YL1 PF05764.13 EEQ40048.1 - 1.1 9.3 7.7 1.7 8.7 7.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 EEQ40048.1 - 1.3 7.1 7.5 1.8 6.7 7.5 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EEQ40048.1 - 1.9 6.7 5.8 2.6 6.2 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 EEQ40048.1 - 2.8 8.0 6.0 4.6 7.2 6.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Astro_capsid_p PF12226.8 EEQ40048.1 - 2.8 7.0 5.2 4 6.5 5.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sigma70_ner PF04546.13 EEQ40048.1 - 3.6 7.4 8.6 5.5 6.8 8.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 EEQ40048.1 - 4.8 7.6 15.3 10 6.6 15.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 EEQ40048.1 - 5.9 7.3 10.7 11 6.5 10.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GTP_EFTU PF00009.27 EEQ40049.1 - 6.9e-43 146.5 0.0 1.4e-42 145.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEQ40049.1 - 2.4e-34 118.0 0.2 8.2e-34 116.3 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEQ40049.1 - 6e-08 33.0 1.3 1.8e-07 31.5 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ40049.1 - 0.002 18.2 0.1 0.014 15.5 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.9 EEQ40049.1 - 0.1 11.4 23.4 0.16 10.7 23.4 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ndc1_Nup PF09531.10 EEQ40049.1 - 3.9 6.0 8.2 5.2 5.6 8.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Trypan_PARP PF05887.11 EEQ40049.1 - 5.1 7.1 23.7 2.1 8.3 20.8 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) VHS PF00790.19 EEQ40050.1 - 1.3e-09 38.0 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 VHS domain SGT1 PF07093.11 EEQ40051.1 - 2.5 6.4 22.0 0.027 12.9 1.7 2.1 2 0 0 2 2 2 0 SGT1 protein Use1 PF09753.9 EEQ40053.1 - 0.0044 16.8 0.0 0.0056 16.4 0.0 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 HrpB2 PF09487.10 EEQ40053.1 - 0.02 15.3 0.1 0.026 14.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) AIP3 PF03915.13 EEQ40053.1 - 0.081 12.0 0.0 0.088 11.9 0.0 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 ParA PF10609.9 EEQ40054.1 - 7.5e-93 310.5 0.0 8.3e-93 310.4 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EEQ40054.1 - 1.3e-10 41.4 0.0 2.6e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EEQ40054.1 - 3.6e-06 27.0 0.0 1.3e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EEQ40054.1 - 1.6e-05 24.3 0.0 5.8e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 ATPase MipZ ArsA_ATPase PF02374.15 EEQ40054.1 - 0.00018 20.8 0.1 0.00032 20.0 0.1 1.4 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.6 EEQ40054.1 - 0.0047 16.5 0.1 0.019 14.6 0.2 1.9 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EEQ40054.1 - 0.0075 15.3 0.1 0.012 14.6 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 EEQ40054.1 - 0.018 14.5 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Zn_Tnp_IS1595 PF12760.7 EEQ40054.1 - 0.089 12.8 0.7 5.8 7.0 0.4 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain APS_kinase PF01583.20 EEQ40054.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Nop16 PF09420.10 EEQ40055.1 - 1.2e-53 182.2 13.6 1.7e-53 181.8 13.6 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Terminase_4 PF05119.12 EEQ40055.1 - 0.082 13.4 3.2 0.9 10.0 0.5 2.4 2 0 0 2 2 2 0 Phage terminase, small subunit PMI_typeI PF01238.21 EEQ40056.1 - 9.3e-154 512.1 0.0 1.1e-153 511.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I FliG_N PF14842.6 EEQ40056.1 - 0.024 15.2 0.0 0.049 14.2 0.0 1.5 1 0 0 1 1 1 0 FliG N-terminal domain AraC_binding PF02311.19 EEQ40056.1 - 0.049 13.5 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 AraC-like ligand binding domain Hexapep PF00132.24 EEQ40057.1 - 1.1e-07 31.3 16.0 0.00042 19.9 0.4 5.0 3 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EEQ40057.1 - 0.0043 16.8 9.4 0.0054 16.4 0.3 3.2 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EEQ40057.1 - 0.59 9.0 2.6 0.54 9.1 0.3 1.7 1 1 1 2 2 2 0 L-fucokinase Thioredoxin PF00085.20 EEQ40059.1 - 4.2e-17 62.0 2.2 4.2e-16 58.8 0.0 3.4 5 0 0 5 5 5 1 Thioredoxin Thioredoxin_6 PF13848.6 EEQ40059.1 - 7.2e-06 26.0 0.3 8e-05 22.6 0.0 2.8 3 1 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EEQ40059.1 - 0.0003 21.1 1.4 0.3 11.4 0.1 2.8 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EEQ40059.1 - 0.087 12.2 1.6 0.31 10.3 0.0 2.6 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family ThiF PF00899.21 EEQ40060.1 - 6e-108 359.8 0.0 2.7e-74 249.6 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EEQ40060.1 - 2.3e-89 299.7 0.0 3.3e-89 299.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EEQ40060.1 - 4.1e-35 120.4 0.0 9.7e-35 119.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EEQ40060.1 - 3.6e-28 97.6 0.2 9.4e-28 96.2 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EEQ40060.1 - 5.8e-27 93.7 0.8 1.6e-26 92.2 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E2_bind PF08825.10 EEQ40060.1 - 0.33 11.1 1.9 11 6.3 0.0 3.0 3 0 0 3 3 3 0 E2 binding domain Asp PF00026.23 EEQ40061.1 - 4.5e-10 39.4 0.6 1.1e-09 38.2 0.6 1.7 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ABC_membrane PF00664.23 EEQ40062.1 - 1.6e-43 149.4 2.6 2.3e-43 148.8 2.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ40062.1 - 4e-37 127.8 0.0 6.1e-25 88.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 EEQ40062.1 - 4.3e-06 27.2 0.4 4.3e-06 27.2 0.4 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 EEQ40062.1 - 0.00061 19.7 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EEQ40062.1 - 0.00062 20.0 0.1 0.23 11.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 EEQ40062.1 - 0.00093 18.7 0.0 0.14 11.6 0.0 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EEQ40062.1 - 0.0044 16.8 0.3 0.083 12.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EEQ40062.1 - 0.02 14.8 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 EEQ40062.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 EEQ40062.1 - 0.048 13.8 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain IstB_IS21 PF01695.17 EEQ40062.1 - 0.049 13.4 0.0 1.7 8.3 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 EEQ40062.1 - 0.058 13.6 0.1 7.2 6.9 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EEQ40062.1 - 0.067 12.5 0.0 0.17 11.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EEQ40062.1 - 0.12 12.9 0.0 0.48 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 EEQ40063.1 - 4e-23 82.5 0.7 5.2e-23 82.1 0.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region C_GCAxxG_C_C PF09719.10 EEQ40063.1 - 0.088 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative redox-active protein (C_GCAxxG_C_C) UPF0016 PF01169.19 EEQ40063.1 - 0.85 10.0 11.3 0.48 10.8 1.6 2.7 2 1 0 2 2 2 0 Uncharacterized protein family UPF0016 Zn_clus PF00172.18 EEQ40066.1 - 1.8e-08 34.4 9.0 3.3e-08 33.5 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EEQ40066.1 - 1.5e-06 27.3 0.0 1.5e-05 24.0 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain UDG PF03167.19 EEQ40067.1 - 3.3e-11 43.4 0.0 5.3e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Brr6_like_C_C PF10104.9 EEQ40068.1 - 6.8e-45 152.1 0.0 9.6e-45 151.6 0.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain TFB6 PF17110.5 EEQ40070.1 - 1.3e-13 51.1 0.2 1.3e-13 51.1 0.2 2.7 2 1 2 4 4 4 1 Subunit 11 of the general transcription factor TFIIH TFIID_NTD2 PF04494.15 EEQ40070.1 - 0.0057 16.9 0.1 0.0094 16.2 0.1 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain Vac_ImportDeg PF09783.9 EEQ40071.1 - 2.9e-29 101.9 0.0 9.2e-29 100.3 0.0 1.7 1 1 0 1 1 1 1 Vacuolar import and degradation protein PEMT PF04191.13 EEQ40072.1 - 9.9e-35 119.1 2.9 2e-34 118.2 2.9 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase PIG-X PF08320.12 EEQ40073.1 - 8.7e-44 150.0 0.0 1.8e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ PF00226.31 EEQ40075.1 - 1.5e-24 85.8 4.0 2.3e-24 85.3 4.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EEQ40075.1 - 7.5e-16 58.5 0.0 1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EEQ40075.1 - 8.2e-15 54.9 18.7 1.6e-14 54.0 18.7 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EEQ40075.1 - 4.1e-05 23.5 13.6 7.4e-05 22.6 0.8 2.6 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EEQ40075.1 - 0.98 9.5 11.3 1.1 9.3 1.4 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EEQ40075.1 - 6 7.0 11.3 24 5.1 6.1 2.2 1 1 1 2 2 2 0 Double zinc ribbon ZZ PF00569.17 EEQ40076.1 - 1.3e-08 34.5 2.7 1.3e-08 34.5 2.7 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type C1_2 PF03107.16 EEQ40076.1 - 0.027 14.8 2.9 0.027 14.8 2.9 2.4 2 0 0 2 2 2 0 C1 domain Tubulin_3 PF14881.6 EEQ40077.1 - 2.6e-22 79.4 0.1 5.6e-22 78.3 0.1 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EEQ40077.1 - 6.2e-11 42.6 0.0 1.7e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Sacchrp_dh_C PF16653.5 EEQ40078.1 - 4e-95 318.9 0.0 5.9e-95 318.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EEQ40078.1 - 8.2e-26 90.8 1.3 1.2e-25 90.3 1.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EEQ40078.1 - 5.9e-08 32.9 0.1 1.1e-07 32.0 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EEQ40078.1 - 6.7e-08 32.6 1.2 1.3e-07 31.7 1.2 1.5 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 EEQ40078.1 - 0.002 18.2 0.9 0.0042 17.2 0.9 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EEQ40078.1 - 0.0032 17.9 0.2 0.007 16.8 0.2 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.18 EEQ40078.1 - 0.0063 16.8 1.0 0.016 15.5 0.8 1.7 2 0 0 2 2 2 1 TrkA-N domain NmrA PF05368.13 EEQ40078.1 - 0.018 14.6 0.3 0.03 13.9 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.17 EEQ40078.1 - 0.055 14.1 0.4 0.11 13.1 0.4 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EEQ40078.1 - 0.072 13.9 0.2 0.24 12.2 0.1 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold BRCT PF00533.26 EEQ40078.1 - 0.075 13.4 0.1 0.28 11.6 0.0 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain 3Beta_HSD PF01073.19 EEQ40078.1 - 0.08 11.9 0.2 0.12 11.4 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EEQ40078.1 - 0.15 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Gly_transf_sug PF04488.15 EEQ40079.1 - 9.5e-14 51.8 0.0 2.2e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF4179 PF13786.6 EEQ40079.1 - 0.024 15.1 0.0 0.053 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) DUF1514 PF07438.11 EEQ40079.1 - 0.049 13.5 1.8 24 4.9 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1514) UCMA PF17085.5 EEQ40079.1 - 0.064 13.3 0.5 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Unique cartilage matrix associated protein Mog1 PF04603.12 EEQ40080.1 - 2.7e-33 115.3 0.1 5e-33 114.4 0.1 1.5 1 0 0 1 1 1 1 Ran-interacting Mog1 protein V-ATPase_H_N PF03224.14 EEQ40080.1 - 0.0048 16.2 0.0 0.0057 16.0 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H Npun_R1517 PF18068.1 EEQ40080.1 - 0.065 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Npun R1517 Adaptin_N PF01602.20 EEQ40081.1 - 1.4e-116 390.2 6.4 1.9e-116 389.7 6.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EEQ40081.1 - 4e-62 209.1 3.0 1.5e-60 203.9 0.9 3.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EEQ40081.1 - 1.9e-10 41.0 4.7 7.8e-05 23.0 0.1 5.3 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.22 EEQ40081.1 - 1.4e-07 31.1 0.3 0.063 13.6 0.0 5.6 4 0 0 4 4 4 2 HEAT repeat RIX1 PF08167.12 EEQ40081.1 - 0.00047 19.9 0.2 1.2 8.9 0.1 3.6 3 0 0 3 3 3 2 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EEQ40081.1 - 0.092 13.3 0.7 20 5.8 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat Med7 PF05983.11 EEQ40083.1 - 4.4e-59 199.8 0.6 4.4e-59 199.8 0.6 1.5 2 0 0 2 2 2 1 MED7 protein RSS_P20 PF11757.8 EEQ40083.1 - 0.43 11.0 2.7 0.63 10.5 1.5 1.9 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain DivIC PF04977.15 EEQ40083.1 - 4.8 7.0 6.5 2.8 7.8 0.7 2.7 3 0 0 3 3 3 0 Septum formation initiator zf-rbx1 PF12678.7 EEQ40084.1 - 2.8e-23 81.9 13.7 4.4e-23 81.3 13.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEQ40084.1 - 1.6e-15 56.9 10.3 2.2e-15 56.5 10.3 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EEQ40084.1 - 1.2e-05 25.5 15.7 1.5e-05 25.2 9.7 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ40084.1 - 0.00012 21.8 4.1 0.00012 21.8 4.1 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ40084.1 - 0.0016 18.2 12.7 0.026 14.4 12.7 2.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ40084.1 - 0.0047 16.6 1.9 0.0047 16.6 1.9 2.5 2 1 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EEQ40084.1 - 0.19 11.8 10.2 1.2 9.2 10.2 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EEQ40084.1 - 0.33 11.1 8.4 1.4 9.2 0.4 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-HC5HC2H PF13771.6 EEQ40084.1 - 0.79 10.0 11.5 42 4.5 11.2 2.1 1 1 0 1 1 1 0 PHD-like zinc-binding domain FANCL_C PF11793.8 EEQ40084.1 - 1.9 8.7 11.3 21 5.4 11.4 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.6 EEQ40084.1 - 2.4 8.2 10.5 11 6.1 10.5 2.1 1 1 0 1 1 1 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EEQ40084.1 - 8.7 6.1 15.0 0.3 10.7 5.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PDT PF00800.18 EEQ40085.1 - 1.5e-47 161.8 0.0 2.1e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EEQ40085.1 - 0.0028 17.4 0.0 0.0063 16.3 0.0 1.6 1 0 0 1 1 1 1 ACT domain DUF3046 PF11248.8 EEQ40086.1 - 0.014 15.8 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3046) Bac_luciferase PF00296.20 EEQ40086.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase Ribosomal_L6 PF00347.23 EEQ40088.1 - 1.2e-20 73.9 7.3 1.2e-15 57.9 1.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 peroxidase PF00141.23 EEQ40089.1 - 4.6e-39 134.5 0.0 7.9e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Peroxidase SNF2_N PF00176.23 EEQ40090.1 - 8.9e-72 241.7 2.3 2.1e-71 240.5 2.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ40090.1 - 5.3e-23 81.5 0.1 8.8e-21 74.3 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EEQ40090.1 - 1.8e-18 66.3 0.0 5.8e-18 64.7 0.0 2.0 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 EEQ40090.1 - 2.2e-13 50.6 0.2 2.2e-13 50.6 0.2 3.4 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HSA PF07529.13 EEQ40090.1 - 4.8e-11 42.8 6.1 4.8e-11 42.8 6.1 3.0 2 0 0 2 2 2 1 HSA SnAC PF14619.6 EEQ40090.1 - 4.8e-09 36.7 5.8 4.8e-09 36.7 5.8 4.1 3 1 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex Pam17 PF08566.10 EEQ40091.1 - 2.9e-61 206.1 0.0 3.4e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Transket_pyr PF02779.24 EEQ40092.1 - 4.4e-66 221.9 0.0 8e-66 221.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EEQ40092.1 - 3.7e-58 196.8 0.0 6.7e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EEQ40092.1 - 2.8e-51 173.2 0.0 4.9e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EEQ40092.1 - 2.7e-20 71.7 3.6 2.7e-20 71.7 3.6 2.0 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus R2K_2 PF18299.1 EEQ40092.1 - 0.047 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 baeRF_family12 PF18856.1 EEQ40092.1 - 0.068 13.8 0.1 4.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DUF676 PF05057.14 EEQ40093.1 - 3.6e-37 128.0 0.0 5.6e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 EEQ40093.1 - 0.12 11.5 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GFO_IDH_MocA PF01408.22 EEQ40094.1 - 5.7e-21 75.6 0.0 8.7e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEQ40094.1 - 2.1e-14 53.5 0.0 3.8e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain adh_short PF00106.25 EEQ40095.1 - 9.8e-47 158.9 0.0 1.3e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ40095.1 - 5.1e-29 101.5 0.0 6.5e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ40095.1 - 2.8e-06 27.4 0.0 4.5e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EEQ40095.1 - 0.0017 17.8 0.0 0.021 14.2 0.0 2.3 3 0 0 3 3 3 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EEQ40095.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DNA_pol_lambd_f PF10391.9 EEQ40095.1 - 0.033 14.0 0.0 0.1 12.4 0.0 1.8 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda Eno-Rase_NADH_b PF12242.8 EEQ40095.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HHH_5 PF14520.6 EEQ40095.1 - 0.18 12.4 0.1 24 5.6 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain NAD_binding_10 PF13460.6 EEQ40095.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF836 PF05768.14 EEQ40097.1 - 2.3e-13 50.4 0.1 2.7e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EEQ40097.1 - 7.9e-05 22.8 0.2 0.00012 22.3 0.2 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin PF00085.20 EEQ40098.1 - 2.3e-41 139.9 0.1 3.3e-23 81.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EEQ40098.1 - 6.4e-17 62.0 0.1 4.3e-07 30.4 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EEQ40098.1 - 1.6e-13 50.7 0.0 1.2e-09 37.9 0.1 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EEQ40098.1 - 3.6e-12 46.4 0.3 1.1e-07 32.1 0.0 4.2 2 1 2 4 4 4 2 Thioredoxin-like ERp29 PF07749.12 EEQ40098.1 - 7.2e-10 39.6 0.5 1.4e-09 38.7 0.5 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain AhpC-TSA PF00578.21 EEQ40098.1 - 1.1e-09 38.2 0.1 1.1e-05 25.3 0.0 3.6 2 1 1 3 3 3 2 AhpC/TSA family TraF PF13728.6 EEQ40098.1 - 5.4e-08 32.9 0.0 0.0025 17.7 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EEQ40098.1 - 7.2e-07 29.3 0.1 0.00011 22.3 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EEQ40098.1 - 2.5e-05 24.1 0.3 0.095 12.5 0.0 2.6 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_5 PF13743.6 EEQ40098.1 - 0.00021 21.0 1.3 5.1 6.7 0.0 4.3 2 2 2 4 4 4 1 Thioredoxin Redoxin PF08534.10 EEQ40098.1 - 0.00054 19.7 0.2 0.32 10.7 0.0 2.3 2 0 0 2 2 2 2 Redoxin Glutaredoxin PF00462.24 EEQ40098.1 - 0.00069 19.8 0.2 0.064 13.5 0.1 2.7 2 0 0 2 2 2 1 Glutaredoxin Suc_Fer-like PF06999.12 EEQ40099.1 - 6.5e-54 182.8 0.0 8.4e-54 182.4 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like PIP5K PF01504.18 EEQ40101.1 - 9.3e-96 320.2 0.3 9.3e-96 320.2 0.3 2.0 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase AIM24 PF01987.17 EEQ40102.1 - 2.9e-27 95.8 0.0 3.7e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF155 PF02582.14 EEQ40104.1 - 7.4e-56 189.0 1.1 9.8e-56 188.6 1.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 EEQ40104.1 - 0.0077 16.7 0.1 0.016 15.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 FAST_1 PF06743.15 EEQ40105.1 - 0.029 14.3 1.7 1.9 8.5 0.2 3.5 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 1 DUF5076 PF16826.5 EEQ40105.1 - 0.12 12.3 0.5 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5076) NYD-SP28 PF14772.6 EEQ40105.1 - 0.23 11.5 5.4 10 6.2 0.9 3.1 3 1 0 3 3 3 0 Sperm tail AI-2E_transport PF01594.16 EEQ40105.1 - 0.24 10.5 0.9 3.5 6.7 0.1 2.6 2 0 0 2 2 2 0 AI-2E family transporter DRIM PF07539.12 EEQ40106.1 - 1.4e-163 545.5 4.3 1.4e-163 545.5 4.3 2.2 2 0 0 2 2 2 2 Down-regulated in metastasis Utp12 PF04003.12 EEQ40106.1 - 0.085 13.2 0.2 7.9 6.8 0.0 3.5 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF4042 PF13251.6 EEQ40107.1 - 0.018 14.7 1.9 7.4 6.2 0.0 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) RIX1 PF08167.12 EEQ40107.1 - 0.027 14.2 1.5 0.84 9.4 0.0 3.2 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Tmp39 PF10271.9 EEQ40107.1 - 0.047 12.7 0.4 0.08 11.9 0.4 1.3 1 0 0 1 1 1 0 Putative transmembrane protein DUF4870 PF09685.10 EEQ40108.1 - 0.99 9.5 6.1 1.7 8.8 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4870) HMG_box_2 PF09011.10 EEQ40109.1 - 2.4e-14 53.7 2.3 4.2e-14 52.9 2.3 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 EEQ40109.1 - 1.9e-13 50.6 4.1 3.6e-13 49.7 4.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box DUF3506 PF12014.8 EEQ40109.1 - 0.023 14.7 1.0 0.032 14.3 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) ZZ PF00569.17 EEQ40110.1 - 4.9e-08 32.7 4.2 1.8e-07 30.8 4.2 2.0 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 EEQ40110.1 - 0.1 13.0 5.6 0.24 11.8 5.6 1.6 1 0 0 1 1 1 0 C1 domain Acid_PPase PF12689.7 EEQ40112.1 - 4.8e-54 182.7 0.0 5.7e-54 182.5 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase SPRY PF00622.28 EEQ40114.1 - 3.8e-12 46.4 0.3 1.8e-11 44.2 0.1 2.0 2 0 0 2 2 2 1 SPRY domain ATP-sulfurylase PF01747.17 EEQ40115.1 - 1.6e-83 279.4 0.0 2.4e-83 278.8 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 EEQ40115.1 - 1.8e-51 174.0 0.0 2.7e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 EEQ40115.1 - 0.0027 17.9 0.0 0.023 14.9 0.0 2.2 2 0 0 2 2 2 1 Cytidylyltransferase-like Cytotoxic PF09000.10 EEQ40115.1 - 0.18 12.2 0.0 0.39 11.1 0.0 1.5 1 0 0 1 1 1 0 Cytotoxic 6PGD PF00393.19 EEQ40116.1 - 2.4e-127 424.3 0.0 3.3e-127 423.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EEQ40116.1 - 1.1e-52 178.4 0.0 1.6e-52 177.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EEQ40116.1 - 0.0022 18.6 0.2 0.0045 17.5 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EEQ40116.1 - 0.0059 16.7 0.6 0.018 15.1 0.2 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EEQ40116.1 - 0.021 14.2 0.1 0.054 12.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_11 PF14833.6 EEQ40116.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ANT PF03374.14 EEQ40116.1 - 0.2 12.0 0.0 2.1 8.7 0.0 2.4 3 0 0 3 3 3 0 Phage antirepressor protein KilAC domain p450 PF00067.22 EEQ40118.1 - 3e-51 174.6 0.0 4.2e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NOC3p PF07540.11 EEQ40119.1 - 8.3e-28 96.7 1.6 5.9e-27 94.0 0.1 2.7 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.17 EEQ40119.1 - 3e-19 69.7 1.6 8.7e-19 68.2 0.0 2.4 3 0 0 3 3 3 1 CBF/Mak21 family Lactamase_B_6 PF16661.5 EEQ40120.1 - 1e-64 217.6 0.0 1.6e-64 216.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EEQ40120.1 - 1.3e-27 97.0 0.1 1.3e-27 97.0 0.1 2.8 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EEQ40120.1 - 3e-12 46.8 0.0 1e-10 41.8 0.0 2.6 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EEQ40120.1 - 0.014 15.3 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain DUF603 PF04645.12 EEQ40120.1 - 0.059 13.1 1.1 0.15 11.8 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF603 PhoLip_ATPase_C PF16212.5 EEQ40121.1 - 2.4e-74 250.2 26.2 2.4e-74 250.2 26.2 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEQ40121.1 - 1.2e-18 66.6 0.3 3.3e-18 65.1 0.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EEQ40121.1 - 2e-12 47.0 0.0 6.1e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EEQ40121.1 - 1.3e-09 38.7 4.4 0.0011 19.3 0.8 3.5 2 2 1 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ40121.1 - 1.8e-07 30.9 2.9 2.7e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEQ40121.1 - 0.0008 19.2 0.7 0.0023 17.7 0.2 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase NAC PF01849.18 EEQ40122.1 - 2.5e-18 65.8 2.4 9.9e-18 63.9 0.1 2.6 3 0 0 3 3 3 1 NAC domain Myc_N PF01056.18 EEQ40122.1 - 0.028 14.3 3.0 0.031 14.2 3.0 1.1 1 0 0 1 1 1 0 Myc amino-terminal region AMIN PF11741.8 EEQ40122.1 - 0.037 14.2 0.5 2.8 8.2 0.1 2.3 2 0 0 2 2 2 0 AMIN domain CSN5_C PF18323.1 EEQ40122.1 - 0.8 10.7 5.8 2.4 9.1 5.6 1.9 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain tRNA_bind_2 PF13725.6 EEQ40122.1 - 2.6 7.7 8.8 4.2 7.0 4.7 2.1 2 0 0 2 2 2 0 Possible tRNA binding domain zinc_ribbon_10 PF10058.9 EEQ40123.1 - 1.3e-18 66.5 0.3 2.1e-18 65.7 0.3 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Ima1_N PF09779.9 EEQ40123.1 - 0.22 12.4 1.0 30 5.5 0.0 2.6 2 0 0 2 2 2 0 Ima1 N-terminal domain Totivirus_coat PF05518.11 EEQ40123.1 - 0.69 7.9 2.0 0.96 7.4 2.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein HD_5 PF13487.6 EEQ40124.1 - 0.091 13.0 0.0 0.36 11.1 0.1 1.9 2 0 0 2 2 2 0 HD domain Rho_GDI PF02115.17 EEQ40124.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 RHO protein GDP dissociation inhibitor Ank_4 PF13637.6 EEQ40125.1 - 1.9e-12 47.4 0.6 0.00024 21.6 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ40125.1 - 5.9e-12 46.0 0.9 0.00022 21.8 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ40125.1 - 1.8e-09 37.1 0.4 0.0017 18.7 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 EEQ40125.1 - 1.8e-08 34.2 1.2 9.8e-07 28.6 0.1 3.5 2 1 0 2 2 2 1 KilA-N domain Ank_5 PF13857.6 EEQ40125.1 - 5.6e-07 29.7 1.3 0.4 11.1 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EEQ40125.1 - 4.1e-06 27.0 0.0 0.95 10.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat CCDC53 PF10152.9 EEQ40125.1 - 0.0085 16.5 6.7 0.033 14.6 2.1 2.8 2 0 0 2 2 2 1 Subunit CCDC53 of WASH complex MFS_1 PF07690.16 EEQ40126.1 - 2.1e-41 142.1 27.4 1e-38 133.2 26.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EEQ40126.1 - 4.5e-08 32.0 2.5 7.3e-08 31.3 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 EEQ40126.1 - 0.0038 16.6 0.9 0.0038 16.6 0.9 3.1 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Mod_r PF07200.13 EEQ40127.1 - 7.3e-22 78.0 14.2 8.4e-22 77.9 14.2 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein ALIX_LYPXL_bnd PF13949.6 EEQ40127.1 - 0.00074 18.9 6.1 0.00074 18.9 6.1 1.7 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV HisKA PF00512.25 EEQ40127.1 - 0.019 15.0 0.3 0.081 13.0 0.3 2.0 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF445 PF04286.12 EEQ40127.1 - 0.08 12.7 4.7 0.093 12.5 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) WD-3 PF09765.9 EEQ40127.1 - 0.15 11.4 4.2 0.23 10.7 4.2 1.4 1 1 0 1 1 1 0 WD-repeat region Sipho_Gp157 PF05565.11 EEQ40127.1 - 0.18 11.8 5.4 0.25 11.3 5.4 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 Ndr PF03096.14 EEQ40127.1 - 0.25 10.0 1.7 0.32 9.7 1.7 1.2 1 0 0 1 1 1 0 Ndr family Pyr_redox_2 PF07992.14 EEQ40128.1 - 2.4e-48 164.9 0.0 3e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EEQ40128.1 - 1.2e-10 41.8 0.1 4.9e-10 39.8 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ40128.1 - 0.0016 17.8 0.6 0.067 12.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SWI-SNF_Ssr4 PF08549.10 EEQ40128.1 - 0.17 10.5 0.2 0.26 9.9 0.2 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DUF3112 PF11309.8 EEQ40130.1 - 6.4e-100 333.1 5.4 9.4e-100 332.5 5.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3112) Ctf8 PF09696.10 EEQ40131.1 - 1.9e-30 106.1 0.1 2e-29 102.8 0.1 1.9 1 1 0 1 1 1 1 Ctf8 Y_phosphatase3 PF13350.6 EEQ40132.1 - 1e-61 208.9 0.0 1.5e-61 208.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Hydrolase_4 PF12146.8 EEQ40132.1 - 9.3e-07 28.4 0.2 1.9e-05 24.0 0.2 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ40132.1 - 3.4e-05 23.6 0.3 0.016 14.9 0.0 2.6 1 1 2 3 3 3 2 alpha/beta hydrolase fold Y_phosphatase2 PF03162.13 EEQ40132.1 - 3.6e-05 23.4 0.0 0.00015 21.3 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EEQ40132.1 - 0.0022 18.1 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EEQ40132.1 - 0.0041 16.7 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DLH PF01738.18 EEQ40132.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Gtr1_RagA PF04670.12 EEQ40132.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region EAP30 PF04157.16 EEQ40133.1 - 3.9e-54 183.4 0.0 4.3e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family AsiA PF09010.10 EEQ40133.1 - 0.029 14.5 0.0 0.48 10.6 0.0 2.7 2 1 0 2 2 2 0 Anti-Sigma Factor A AA_permease_N PF08403.10 EEQ40133.1 - 0.056 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Amino acid permease N-terminal PseudoU_synth_1 PF01416.20 EEQ40134.1 - 1.6e-34 118.6 0.0 3.1e-32 111.2 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEAD PF00270.29 EEQ40135.1 - 4.5e-25 88.4 1.1 1.1e-24 87.2 0.3 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ40135.1 - 1.1e-23 83.6 2.4 2.4e-23 82.6 0.0 2.8 4 1 1 5 5 5 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEQ40135.1 - 7.1e-17 61.4 0.8 1.4e-16 60.4 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Pet20 PF08692.10 EEQ40135.1 - 0.094 13.4 1.7 0.41 11.4 1.7 2.2 1 1 0 1 1 1 0 Mitochondrial protein Pet20 AAA_11 PF13086.6 EEQ40135.1 - 0.22 11.3 9.3 4.3 7.0 4.2 2.9 2 1 0 3 3 3 0 AAA domain FAM177 PF14774.6 EEQ40135.1 - 4.4 7.7 14.0 8.9 6.7 5.7 2.8 3 0 0 3 3 3 0 FAM177 family ThiF PF00899.21 EEQ40136.1 - 5.8e-23 81.5 0.0 8.6e-23 81.0 0.0 1.4 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 EEQ40136.1 - 0.003 17.7 0.2 4.6 7.5 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin-activating enzyme E1 four-helix bundle DHR-2 PF06920.13 EEQ40136.1 - 0.11 11.2 1.0 0.18 10.4 1.0 1.4 1 1 0 1 1 1 0 Dock homology region 2 DUF4197 PF13852.6 EEQ40136.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4197) SPX PF03105.19 EEQ40137.1 - 3.7e-44 152.2 16.9 5.6e-44 151.6 16.9 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.6 EEQ40137.1 - 1.2e-08 35.0 8.3 2.2e-08 34.1 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EEQ40137.1 - 2.5e-08 34.1 8.5 5e-08 33.2 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ40137.1 - 3.7e-08 33.1 9.0 8.2e-08 32.0 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ40137.1 - 4.5e-07 29.6 11.2 8.1e-07 28.8 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ40137.1 - 4.8e-07 29.5 9.1 1e-06 28.5 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ40137.1 - 9.4e-07 28.8 6.5 2.1e-06 27.6 6.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ40137.1 - 7.1e-05 22.7 11.0 0.00024 21.0 11.2 1.8 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ40137.1 - 0.00033 20.4 10.2 0.0035 17.2 10.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EEQ40137.1 - 0.012 15.9 5.9 0.036 14.3 5.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 EEQ40137.1 - 0.068 13.3 6.7 0.18 12.0 6.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EEQ40137.1 - 0.12 12.1 11.5 1.2 9.0 11.8 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EEQ40137.1 - 0.23 11.4 3.6 0.49 10.3 3.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_5 PF17121.5 EEQ40137.1 - 0.85 9.6 10.8 3.4 7.6 10.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TerY_C PF15616.6 EEQ40137.1 - 1.7 8.7 6.0 6.4 6.9 5.6 2.1 1 1 1 2 2 2 0 TerY-C metal binding domain DUF4404 PF14357.6 EEQ40137.1 - 4.2 8.1 13.5 16 6.2 1.2 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) MinE PF03776.14 EEQ40137.1 - 5 7.2 8.6 1.6 8.8 0.6 3.2 3 0 0 3 3 3 0 Septum formation topological specificity factor MinE Thioredoxin_4 PF13462.6 EEQ40137.1 - 6.4 6.9 11.2 0.15 12.2 0.6 3.4 4 1 0 4 4 4 0 Thioredoxin ArsA_ATPase PF02374.15 EEQ40140.1 - 1.2e-106 356.4 0.2 1.3e-106 356.2 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EEQ40140.1 - 6.2e-08 32.8 0.6 2.1e-07 31.0 0.1 2.1 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 EEQ40140.1 - 1.9e-07 31.2 0.1 5.2e-07 29.8 0.1 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EEQ40140.1 - 0.0005 19.6 4.9 0.031 13.7 1.9 2.7 2 1 1 3 3 3 2 NUBPL iron-transfer P-loop NTPase NB-ARC PF00931.22 EEQ40140.1 - 0.0046 16.2 0.0 0.03 13.5 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain Fer4_NifH PF00142.18 EEQ40140.1 - 0.012 15.1 0.1 0.03 13.8 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Zeta_toxin PF06414.12 EEQ40140.1 - 0.022 14.1 0.0 0.052 12.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin PIF1 PF05970.14 EEQ40140.1 - 0.022 14.0 0.1 2.2 7.4 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_24 PF13479.6 EEQ40140.1 - 0.04 13.6 0.1 0.36 10.5 0.1 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EEQ40140.1 - 0.063 12.9 0.1 0.34 10.5 0.0 2.1 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain DLH PF01738.18 EEQ40141.1 - 2.8e-28 99.0 0.0 3.5e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EEQ40141.1 - 0.0017 17.8 0.0 0.0063 16.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EEQ40141.1 - 0.0054 16.4 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 EEQ40141.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase BAAT_C PF08840.11 EEQ40141.1 - 0.023 14.6 0.0 0.084 12.8 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal WD40 PF00400.32 EEQ40142.1 - 2.4e-22 78.8 1.2 0.00012 22.8 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ40142.1 - 3e-10 40.3 0.0 0.01 16.1 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SdiA-regulated PF06977.11 EEQ40142.1 - 0.015 14.5 0.0 6.4 5.9 0.0 2.8 3 0 0 3 3 3 0 SdiA-regulated RTX_C PF08339.10 EEQ40142.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 RTX C-terminal domain SGL PF08450.12 EEQ40142.1 - 0.077 12.6 0.3 1 8.9 0.1 2.6 1 1 2 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region Homeodomain PF00046.29 EEQ40143.1 - 1.6e-15 56.7 4.9 2.8e-15 55.9 4.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EEQ40143.1 - 0.29 11.1 4.2 0.21 11.5 0.9 2.4 3 0 0 3 3 3 0 Homeobox KN domain Ribosomal_L10 PF00466.20 EEQ40145.1 - 3.6e-25 88.0 0.7 9.9e-25 86.6 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EEQ40145.1 - 3.7e-23 81.3 0.0 5.9e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EEQ40145.1 - 1.8e-21 76.5 7.7 8.3e-21 74.4 5.9 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein RRG8 PF17068.5 EEQ40146.1 - 0.16 11.4 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial Ribosomal_S16 PF00886.19 EEQ40148.1 - 4.7e-23 81.0 0.0 7.5e-23 80.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 NUC173 PF08161.12 EEQ40149.1 - 1e-73 247.4 7.6 2.7e-70 236.2 0.2 3.8 4 1 1 5 5 5 2 NUC173 domain Ipi1_N PF12333.8 EEQ40149.1 - 0.023 15.3 0.1 14 6.3 0.0 3.9 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF1708 PF08101.11 EEQ40149.1 - 0.12 11.5 3.4 0.054 12.7 0.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1708) L51_S25_CI-B8 PF05047.16 EEQ40150.1 - 1.9e-10 40.5 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain FTR_C PF02741.15 EEQ40150.1 - 0.011 15.7 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 FTR, proximal lobe LigB PF02900.18 EEQ40151.1 - 6.9e-18 64.7 0.0 9.3e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase BTB PF00651.31 EEQ40153.1 - 2.4e-12 47.0 0.0 8.4e-06 26.0 0.0 3.1 2 1 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 EEQ40153.1 - 2.2e-05 24.9 0.0 0.00011 22.8 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ40153.1 - 2.5e-05 24.4 0.0 7.7e-05 22.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ40153.1 - 0.01 16.3 0.1 1.8 9.4 0.1 3.4 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 EEQ40153.1 - 0.015 15.8 0.1 0.1 13.1 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_4 PF13637.6 EEQ40153.1 - 0.021 15.4 0.1 0.077 13.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) PEP-utilisers_N PF05524.13 EEQ40153.1 - 0.45 10.7 2.5 9.6 6.4 0.2 2.8 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal PNGaseA PF12222.8 EEQ40154.1 - 1.7e-27 96.4 3.4 2.9e-27 95.6 3.4 1.3 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DcpS_C PF11969.8 EEQ40155.1 - 1.2e-35 122.4 3.1 1e-34 119.4 0.2 2.5 2 1 1 3 3 3 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 EEQ40155.1 - 3.3e-31 108.2 0.4 5.2e-31 107.6 0.4 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.23 EEQ40155.1 - 0.06 14.1 0.3 0.16 12.8 0.3 1.8 1 1 0 1 1 1 0 HIT domain DEAD PF00270.29 EEQ40156.1 - 1.8e-44 151.6 0.1 3.3e-44 150.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ40156.1 - 2.5e-18 66.4 0.0 9.4e-18 64.6 0.0 2.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EEQ40156.1 - 2.6e-18 66.0 0.1 6.1e-18 64.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EEQ40156.1 - 3e-08 33.9 1.1 1.5e-07 31.5 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SIR2_2 PF13289.6 EEQ40156.1 - 0.027 14.6 0.2 2 8.5 0.0 2.6 2 0 0 2 2 2 0 SIR2-like domain UvrD-helicase PF00580.21 EEQ40156.1 - 0.12 11.9 0.1 0.12 11.9 0.1 2.0 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Sin_N PF04801.13 EEQ40157.1 - 3.6e-20 72.6 0.6 8.6e-20 71.4 0.6 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region MF_alpha_N PF05436.11 EEQ40159.1 - 1.6e-05 24.7 0.1 2.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus Apidaecin PF00807.17 EEQ40159.1 - 0.71 10.0 5.4 28 4.9 0.0 3.9 4 0 0 4 4 4 0 Apidaecin RRP14 PF15459.6 EEQ40160.1 - 2.9 8.6 10.2 1.4 9.5 3.9 2.2 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 UCH_1 PF13423.6 EEQ40161.1 - 5.7e-53 180.6 2.4 8.2e-53 180.1 2.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EEQ40161.1 - 2.1e-21 77.1 0.0 5.3e-21 75.8 0.0 1.7 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 EEQ40161.1 - 2.9e-06 27.0 3.5 4.8e-06 26.3 3.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TCO89 PF10452.9 EEQ40162.1 - 1.3e-11 44.2 33.2 1.9e-08 33.8 1.6 3.2 2 1 1 3 3 3 2 TORC1 subunit TCO89 Ribosomal_L36 PF00444.18 EEQ40163.1 - 4.6e-20 71.5 10.8 7.9e-20 70.8 10.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.17 EEQ40163.1 - 0.012 15.4 1.1 0.02 14.7 1.1 1.3 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Ribosomal_L28 PF00830.19 EEQ40164.1 - 1.2e-09 38.2 3.1 1.2e-09 38.2 3.1 1.8 2 0 0 2 2 2 1 Ribosomal L28 family Pkinase PF00069.25 EEQ40165.1 - 2.2e-69 233.8 0.0 3e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40165.1 - 3.2e-30 105.3 0.0 5e-30 104.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EEQ40165.1 - 3.1e-14 53.4 1.3 1.6e-13 51.1 1.3 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 EEQ40165.1 - 2.4e-09 37.4 0.1 2e-06 28.0 0.0 2.7 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 EEQ40165.1 - 6.6e-09 35.5 0.0 4.1e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EEQ40165.1 - 0.0014 17.6 0.0 0.0031 16.5 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EEQ40165.1 - 0.031 13.9 0.1 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RskA PF10099.9 EEQ40165.1 - 0.058 13.7 2.0 0.094 13.0 2.0 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA APH PF01636.23 EEQ40165.1 - 0.08 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EEQ40165.1 - 0.083 12.4 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.14 EEQ40165.1 - 0.093 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Adeno_E3_15_3 PF03307.14 EEQ40165.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region Pkinase_fungal PF17667.1 EEQ40165.1 - 0.27 10.0 0.8 0.57 8.9 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase RuvX PF03652.15 EEQ40166.1 - 0.058 13.8 0.1 0.11 12.9 0.1 1.4 1 0 0 1 1 1 0 Holliday junction resolvase Phosphodiest PF01663.22 EEQ40167.1 - 1.1e-12 48.2 0.3 1.7e-12 47.6 0.3 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EEQ40167.1 - 0.0011 18.4 0.4 0.003 17.0 0.2 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 EEQ40167.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Sulfatase GATase_4 PF13230.6 EEQ40168.1 - 2.1e-13 49.8 0.1 9.1e-13 47.7 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EEQ40168.1 - 7.8e-12 45.5 0.0 1.3e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain SAPS PF04499.15 EEQ40169.1 - 3.2e-191 636.4 6.3 3.2e-191 636.4 6.3 3.7 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Com_YlbF PF06133.11 EEQ40169.1 - 0.093 13.3 2.3 1.8 9.2 0.1 3.1 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Ribosomal_L21p PF00829.21 EEQ40171.1 - 1.3e-11 44.6 0.0 1.6e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.25 EEQ40172.1 - 5.9e-71 238.9 0.1 1.5e-70 237.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40172.1 - 1.9e-48 165.0 0.0 3.7e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ40172.1 - 5e-12 45.7 0.0 1.2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like SAM_2 PF07647.17 EEQ40172.1 - 0.00081 19.5 0.1 0.0021 18.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EEQ40172.1 - 0.0081 16.6 0.1 0.021 15.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Sfi1 PF08457.10 EEQ40173.1 - 7.8e-29 100.6 65.4 3.7e-28 98.4 55.4 2.7 1 1 3 4 4 4 3 Sfi1 spindle body protein FhuF PF06276.12 EEQ40173.1 - 0.0039 17.6 0.7 0.014 15.8 0.4 2.2 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter Imm3 PF14425.6 EEQ40173.1 - 0.09 12.8 0.3 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 Immunity protein Imm3 Glyco_hydro_59 PF02057.15 EEQ40173.1 - 2.1 7.5 7.6 0.18 11.0 1.8 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 Glyco_transf_22 PF03901.17 EEQ40174.1 - 1.3e-35 123.4 19.4 1.7e-35 123.0 19.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3413 PF11893.8 EEQ40174.1 - 0.91 8.6 12.1 0.059 12.5 3.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) cobW PF02492.19 EEQ40175.1 - 3.7e-41 140.6 1.2 5.4e-41 140.1 1.2 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EEQ40175.1 - 2.3e-09 37.0 0.0 4.3e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.6 EEQ40175.1 - 0.0004 20.1 0.0 0.00098 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ40175.1 - 0.00073 19.5 0.2 1.3 8.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEQ40175.1 - 0.0014 18.7 0.0 0.0039 17.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ40175.1 - 0.0018 18.7 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EEQ40175.1 - 0.023 15.2 0.2 0.14 12.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EEQ40175.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EEQ40175.1 - 0.059 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EEQ40175.1 - 0.065 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EEQ40175.1 - 0.082 12.9 0.0 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Tim54 PF11711.8 EEQ40176.1 - 4.3e-128 427.2 3.1 9e-128 426.2 3.1 1.5 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 ELFV_dehydrog PF00208.21 EEQ40177.1 - 4.7e-87 291.7 3.3 5.6e-87 291.5 3.3 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EEQ40177.1 - 4.5e-50 168.9 0.0 9.7e-50 167.8 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF1678 PF07913.11 EEQ40178.1 - 0.09 12.5 0.1 0.68 9.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1678) zf-Nse PF11789.8 EEQ40179.1 - 5.9e-21 74.0 0.1 9.8e-21 73.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.6 EEQ40179.1 - 0.00046 20.0 0.1 0.00093 19.0 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ40179.1 - 0.00061 19.8 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EEQ40179.1 - 0.023 15.0 0.3 0.042 14.2 0.3 1.4 1 0 0 1 1 1 0 Ring finger domain Zn-ribbon_8 PF09723.10 EEQ40179.1 - 0.058 13.5 0.4 0.11 12.6 0.4 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_4 PF15227.6 EEQ40179.1 - 0.14 12.4 0.1 0.37 11.0 0.1 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Phosphodiest PF01663.22 EEQ40180.1 - 1.1e-87 294.9 1.7 2.1e-87 294.0 1.7 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Plant_vir_prot PF01307.17 EEQ40180.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.4 1 0 0 1 1 1 0 Plant viral movement protein MGC-24 PF05283.11 EEQ40180.1 - 1.7 9.1 4.9 2.9 8.3 4.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin NIF3 PF01784.18 EEQ40181.1 - 3.1e-58 197.3 0.0 3.7e-58 197.0 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) UN_NPL4 PF11543.8 EEQ40181.1 - 0.12 12.9 0.0 0.69 10.4 0.0 2.1 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 MFS_1 PF07690.16 EEQ40182.1 - 1.6e-22 79.9 31.6 1.1e-17 64.0 3.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily BolA PF01722.18 EEQ40183.1 - 2.9e-18 65.9 0.1 7.4e-18 64.6 0.1 1.6 1 1 0 1 1 1 1 BolA-like protein RhoGAP PF00620.27 EEQ40184.1 - 7.9e-36 123.2 0.1 1.7e-35 122.1 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EEQ40184.1 - 9.2e-30 102.7 44.5 3.9e-11 43.0 6.8 4.4 4 0 0 4 4 4 4 LIM domain DUF3645 PF12359.8 EEQ40184.1 - 0.05 13.0 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3645) zinc_ribbon_12 PF11331.8 EEQ40184.1 - 0.052 13.4 0.1 0.052 13.4 0.1 3.6 4 0 0 4 4 4 0 Probable zinc-ribbon domain PIG-H PF10181.9 EEQ40185.1 - 3.4e-24 84.5 0.1 6.4e-24 83.6 0.1 1.5 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component LapA_dom PF06305.11 EEQ40185.1 - 0.0022 17.8 3.3 0.046 13.5 0.1 2.5 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain Pico_P2B PF01552.17 EEQ40185.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 Picornavirus 2B protein Myb_DNA-bind_7 PF15963.5 EEQ40186.1 - 7.7e-27 93.0 0.7 7.7e-27 93.0 0.7 2.3 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EEQ40186.1 - 1.7e-07 31.3 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ40186.1 - 0.0056 16.9 0.1 0.014 15.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EEQ40186.1 - 0.14 12.3 1.3 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 WD40 PF00400.32 EEQ40187.1 - 5.7e-07 30.1 5.2 0.058 14.3 0.2 5.0 4 0 0 4 4 4 2 WD domain, G-beta repeat Hist_deacetyl PF00850.19 EEQ40188.1 - 7.4e-90 301.5 0.0 9.4e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain CDC45 PF02724.14 EEQ40188.1 - 0.042 12.2 1.6 0.061 11.6 1.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 EEQ40188.1 - 0.66 8.7 2.2 0.87 8.3 2.2 1.1 1 0 0 1 1 1 0 Raftlin LAP1C PF05609.12 EEQ40188.1 - 1.7 7.6 6.8 2.4 7.1 6.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Arb2 PF09757.9 EEQ40189.1 - 4.9e-52 176.6 0.0 4.1e-50 170.3 0.0 2.0 1 1 0 1 1 1 1 Arb2 domain Pkinase PF00069.25 EEQ40190.1 - 3.6e-42 144.5 0.0 6.3e-42 143.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40190.1 - 1.5e-28 99.8 0.0 1.8e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ40190.1 - 0.0033 16.8 0.0 0.019 14.3 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ40190.1 - 0.14 12.1 0.0 0.45 10.4 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltr_RsmB-F PF01189.17 EEQ40191.1 - 2.8e-21 76.1 0.0 4.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 EEQ40191.1 - 0.002 17.3 0.0 0.0079 15.3 0.0 1.9 2 0 0 2 2 2 1 Fibrillarin Methyltr_RsmF_N PF17125.5 EEQ40191.1 - 0.033 14.7 0.1 0.51 10.9 0.0 2.8 1 1 1 2 2 2 0 N-terminal domain of 16S rRNA methyltransferase RsmF Transp_cyt_pur PF02133.15 EEQ40193.1 - 8.5e-148 492.8 35.0 9.8e-148 492.6 35.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin VWA_3 PF13768.6 EEQ40193.1 - 0.13 12.2 0.0 0.59 10.1 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain GrpE PF01025.19 EEQ40194.1 - 3.1e-49 166.8 16.3 1.7e-48 164.4 16.3 1.8 1 1 0 1 1 1 1 GrpE RRN3 PF05327.11 EEQ40194.1 - 0.81 8.1 7.3 1.1 7.8 7.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 O-antigen_lig PF13425.6 EEQ40194.1 - 0.95 8.2 4.0 1.3 7.7 4.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Dynactin_p62 PF05502.13 EEQ40194.1 - 2.2 7.0 6.7 2.6 6.7 6.7 1.2 1 0 0 1 1 1 0 Dynactin p62 family Prominin PF05478.11 EEQ40194.1 - 3.9 5.3 5.9 4.6 5.1 5.9 1.1 1 0 0 1 1 1 0 Prominin ALMT PF11744.8 EEQ40194.1 - 4.3 6.1 7.6 5.9 5.6 7.6 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 EEQ40194.1 - 5.6 6.2 9.9 7.2 5.9 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5098 PF17023.5 EEQ40194.1 - 6 5.7 14.8 0.021 13.8 4.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5098) DDE_3 PF13358.6 EEQ40196.1 - 6.8e-25 87.5 0.0 8.9e-18 64.4 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease HTH_Tnp_1 PF01527.20 EEQ40196.1 - 0.00014 22.1 1.4 0.00019 21.7 0.3 1.8 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 EEQ40196.1 - 0.0026 17.9 0.1 0.0069 16.5 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.6 EEQ40196.1 - 0.0032 17.2 0.1 0.0083 15.9 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain DUF1804 PF08822.11 EEQ40196.1 - 0.16 11.9 0.5 0.39 10.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) Abhydrolase_1 PF00561.20 EEQ40197.1 - 1.7e-10 41.0 0.1 1.1e-08 35.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ40197.1 - 9.4e-10 39.5 0.0 6.8e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ40197.1 - 4.9e-09 35.8 0.0 8.3e-05 22.0 0.0 3.2 3 0 0 3 3 3 3 Serine aminopeptidase, S33 Esterase PF00756.20 EEQ40197.1 - 0.0071 16.0 0.1 0.02 14.5 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Sulfate_transp PF00916.20 EEQ40198.1 - 1.6e-74 251.0 22.3 3.8e-74 249.7 22.3 1.6 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEQ40198.1 - 2.4e-15 56.2 0.1 4.7e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 STAS domain Tho1_MOS11_C PF18592.1 EEQ40198.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Tho1/MOS11 C-terminal domain COX8 PF02285.15 EEQ40198.1 - 0.58 10.1 3.0 7.1 6.6 0.2 3.1 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII Oxidored-like PF09791.9 EEQ40199.1 - 4.2e-25 87.1 3.6 4.2e-25 87.1 3.6 1.9 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal DPM3 PF08285.11 EEQ40200.1 - 3.4e-31 107.3 0.1 3.8e-31 107.1 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 EEQ40200.1 - 0.06 13.4 0.2 0.07 13.2 0.2 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF1129 PF06570.11 EEQ40200.1 - 0.09 12.3 0.9 0.11 11.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Tau95 PF09734.9 EEQ40201.1 - 7.4e-38 130.5 1.1 7.4e-38 130.5 1.1 2.4 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EEQ40201.1 - 4.4e-29 101.2 0.2 1.1e-28 99.9 0.2 1.7 1 0 0 1 1 1 1 Tau95 Triple barrel domain DNA_pol_phi PF04931.13 EEQ40201.1 - 0.56 8.2 18.3 0.93 7.5 18.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 EEQ40201.1 - 1.4 8.0 21.5 2.3 7.2 21.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 EEQ40201.1 - 3.8 6.7 12.1 5.4 6.3 12.1 1.2 1 0 0 1 1 1 0 BUD22 FYDLN_acid PF09538.10 EEQ40201.1 - 5.1 7.8 17.3 15 6.4 17.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Ldh_1_C PF02866.18 EEQ40202.1 - 1.1e-46 158.8 0.1 2.1e-46 157.9 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EEQ40202.1 - 9.6e-46 155.4 0.1 1.6e-45 154.6 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EEQ40202.1 - 0.00048 19.2 0.0 0.00074 18.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EEQ40202.1 - 0.0038 16.8 0.5 2.5 7.6 0.3 2.7 2 1 1 3 3 3 2 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 EEQ40202.1 - 0.026 13.9 0.3 0.23 10.7 0.0 2.4 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Semialdhyde_dh PF01118.24 EEQ40202.1 - 0.046 14.1 0.1 0.25 11.8 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF4574 PF15141.6 EEQ40202.1 - 0.073 13.0 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 zf-C2H2 PF00096.26 EEQ40204.1 - 1.2e-06 28.6 17.6 7.8e-06 26.1 0.5 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ40204.1 - 2.9e-06 27.6 11.8 0.0073 17.1 0.3 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 EEQ40204.1 - 6.1e-05 23.3 0.4 0.073 13.5 0.5 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 EEQ40204.1 - 0.0006 20.1 14.9 0.00098 19.5 2.1 3.5 3 0 0 3 3 3 2 Zinc-finger double domain ARS2 PF04959.13 EEQ40204.1 - 0.019 15.3 0.3 0.058 13.8 0.3 1.8 1 0 0 1 1 1 0 Arsenite-resistance protein 2 zf-C2H2_6 PF13912.6 EEQ40204.1 - 0.27 11.3 8.6 5.9 7.0 1.6 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ40204.1 - 0.33 11.3 4.9 2.6 8.4 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 EEQ40204.1 - 9.5 6.1 9.1 2.6 7.9 1.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Aminotran_1_2 PF00155.21 EEQ40205.1 - 1.5e-58 198.8 0.0 1.7e-58 198.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HEAT_2 PF13646.6 EEQ40206.1 - 0.0094 16.3 2.5 0.1 13.0 0.1 3.6 3 1 0 3 3 3 1 HEAT repeats NIF PF03031.18 EEQ40207.1 - 1.5e-46 158.1 0.2 4.6e-46 156.4 0.2 1.7 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Sarcolipin PF05366.11 EEQ40207.1 - 0.042 13.6 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 Sarcolipin zinc_ribbon_6 PF14599.6 EEQ40208.1 - 1.3e-22 79.6 2.3 1.3e-22 79.6 2.3 3.1 2 1 0 2 2 2 1 Zinc-ribbon zf-CHY PF05495.12 EEQ40208.1 - 2.2e-16 60.1 19.7 2.2e-16 60.1 19.7 3.9 3 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EEQ40208.1 - 6.5e-08 32.8 9.5 6.5e-08 32.8 9.5 5.2 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ40208.1 - 6.7e-06 25.8 7.4 6.7e-06 25.8 7.4 5.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ40208.1 - 7.7e-06 25.8 10.9 7.7e-06 25.8 10.9 5.7 3 2 3 6 6 6 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EEQ40208.1 - 0.00026 20.8 9.8 0.00026 20.8 9.8 6.0 3 2 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 EEQ40208.1 - 0.015 15.2 3.8 0.015 15.2 3.8 5.1 4 3 3 7 7 7 0 Prokaryotic RING finger family 1 Presenilin PF01080.17 EEQ40208.1 - 0.49 9.1 2.0 0.85 8.3 2.0 1.4 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 EEQ40208.1 - 3 6.8 15.7 0.058 12.5 8.4 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) PRP21_like_P PF12230.8 EEQ40209.1 - 2.1e-59 201.0 20.6 3.8e-59 200.2 20.6 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EEQ40209.1 - 1e-26 92.6 2.6 7.1e-15 54.7 0.2 2.8 2 0 0 2 2 2 2 Surp module Sporozoite_P67 PF05642.11 EEQ40209.1 - 0.31 9.1 6.0 0.43 8.6 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SspB PF04386.13 EEQ40209.1 - 5.1 7.0 11.6 1.6 8.6 7.4 2.2 2 0 0 2 2 2 0 Stringent starvation protein B Ribosomal_S6e PF01092.19 EEQ40211.1 - 7.1e-62 207.0 0.1 1.3e-61 206.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e VKG_Carbox PF05090.14 EEQ40211.1 - 0.27 10.0 0.2 0.34 9.7 0.2 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase DUF4574 PF15141.6 EEQ40211.1 - 0.84 9.6 4.9 1.5 8.7 4.9 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 SRF-TF PF00319.18 EEQ40212.1 - 1.6e-21 75.5 0.1 2.7e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Poxvirus_B22R PF04395.12 EEQ40212.1 - 0.09 12.3 0.3 0.13 11.8 0.3 1.2 1 0 0 1 1 1 0 Poxvirus B22R protein Sec16_C PF12931.7 EEQ40213.1 - 9.1e-66 222.5 0.1 1.6e-65 221.7 0.1 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EEQ40213.1 - 2.2e-09 37.9 0.0 1.7e-08 35.1 0.0 2.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Acetyltransf_1 PF00583.25 EEQ40214.1 - 8e-05 22.8 0.1 0.0022 18.2 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ40214.1 - 0.0019 18.6 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Arm-DNA-bind_5 PF17293.2 EEQ40215.1 - 0.0033 17.8 1.1 0.0033 17.8 1.1 2.1 1 1 1 2 2 2 1 Arm DNA-binding domain FAD_binding_8 PF08022.12 EEQ40216.1 - 8.6e-24 83.7 0.1 1.9e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EEQ40216.1 - 1.1e-21 77.2 10.3 1.1e-21 77.2 10.3 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ40216.1 - 1.1e-19 71.1 0.0 2.6e-19 69.9 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain SKG6 PF08693.10 EEQ40217.1 - 1e-05 24.8 0.1 2.2e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Orf78 PF06024.12 EEQ40217.1 - 0.13 12.5 0.7 0.61 10.4 0.0 2.4 3 0 0 3 3 3 0 Orf78 (ac78) Ribosomal_S4 PF00163.19 EEQ40218.1 - 4.8e-12 46.6 1.0 7.3e-12 46.0 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EEQ40218.1 - 1.8e-09 37.1 0.1 2e-08 33.8 0.0 2.4 3 0 0 3 3 3 1 S4 domain Herpes_LAMP2 PF06126.11 EEQ40218.1 - 0.12 11.0 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Pox_A_type_inc PF04508.12 EEQ40218.1 - 0.12 12.2 0.1 0.91 9.5 0.0 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Ribosomal_L6 PF00347.23 EEQ40219.1 - 6.7e-23 81.2 2.9 6.4e-11 42.8 1.2 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 Ribosomal_L3 PF00297.22 EEQ40220.1 - 4.5e-18 65.4 3.1 4.4e-16 58.8 0.8 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 OAM_dimer PF16554.5 EEQ40220.1 - 0.097 13.1 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase polyprenyl_synt PF00348.17 EEQ40222.1 - 6.5e-66 222.0 0.0 5.5e-64 215.7 0.0 2.9 1 1 0 1 1 1 1 Polyprenyl synthetase Trehalase PF01204.18 EEQ40223.1 - 7.5e-160 533.1 0.2 8.8e-160 532.9 0.2 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EEQ40223.1 - 3.3e-17 61.9 0.5 6.3e-17 61.0 0.5 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain hEGF PF12661.7 EEQ40225.1 - 0.39 11.4 4.6 1.3 9.8 4.6 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF Ldh_1_C PF02866.18 EEQ40226.1 - 3.7e-43 147.4 0.0 5.7e-43 146.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EEQ40226.1 - 2.3e-42 144.4 0.7 3.8e-42 143.7 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EEQ40226.1 - 0.042 12.9 0.0 0.062 12.3 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family CRM1_C PF08767.11 EEQ40227.1 - 3.6e-125 417.4 3.5 3.6e-125 417.4 3.5 2.9 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EEQ40227.1 - 8.1e-36 123.3 4.7 8.1e-36 123.3 4.7 3.5 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EEQ40227.1 - 5.7e-34 115.6 3.2 1.7e-33 114.1 3.2 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EEQ40227.1 - 1.6e-28 98.6 3.4 3.7e-28 97.4 1.7 2.7 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 IBN_N PF03810.19 EEQ40227.1 - 3.4e-14 52.5 0.1 2e-13 50.0 0.1 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain CRM1_repeat PF18777.1 EEQ40227.1 - 6.4e-14 51.2 2.2 6.4e-14 51.2 2.2 2.6 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat DUF1981 PF09324.10 EEQ40227.1 - 0.047 13.6 0.0 11 5.9 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) Ran_BP1 PF00638.18 EEQ40228.1 - 1e-52 177.5 2.5 1.8e-52 176.8 2.5 1.4 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EEQ40228.1 - 8.5e-05 22.5 0.3 0.00096 19.1 0.3 2.1 1 1 0 1 1 1 1 WH1 domain Lig_C PF18330.1 EEQ40228.1 - 0.019 14.9 0.6 0.083 12.9 0.0 2.2 2 1 0 2 2 2 0 Ligase Pab1020 C-terminal region Cellulose_synt PF03552.14 EEQ40228.1 - 0.053 12.0 2.1 0.077 11.5 2.1 1.1 1 0 0 1 1 1 0 Cellulose synthase TMEM214 PF10151.9 EEQ40228.1 - 1.4 7.3 8.4 1.9 6.9 8.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Sec62 PF03839.16 EEQ40228.1 - 1.5 8.3 8.1 2.2 7.7 8.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Ank_2 PF12796.7 EEQ40229.1 - 1.1e-25 90.0 0.4 1.2e-10 41.8 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ40229.1 - 5.1e-21 74.8 0.4 2.1e-05 25.0 0.1 4.5 2 1 1 4 4 4 4 Ankyrin repeats (many copies) SPX PF03105.19 EEQ40229.1 - 6.3e-16 59.3 20.6 1.3e-07 31.9 0.7 4.2 3 1 2 5 5 5 3 SPX domain Ank_3 PF13606.6 EEQ40229.1 - 7e-16 56.7 0.4 0.028 15.0 0.0 7.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EEQ40229.1 - 6.4e-13 48.6 0.1 0.013 15.8 0.1 5.5 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EEQ40229.1 - 2.4e-12 46.7 0.0 0.084 13.4 0.1 6.3 6 0 0 6 6 6 3 Ankyrin repeat DUF2013 PF09431.10 EEQ40230.1 - 7e-40 136.4 5.0 7e-40 136.4 5.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) BCDHK_Adom3 PF10436.9 EEQ40231.1 - 2.7e-30 105.4 0.2 4.1e-30 104.8 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EEQ40231.1 - 5.9e-11 42.9 0.0 1.6e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EEQ40231.1 - 0.00051 19.9 0.0 0.00089 19.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EEQ40231.1 - 0.047 13.6 0.0 0.097 12.6 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-like ATPase domain Cupin_8 PF13621.6 EEQ40232.1 - 9.4e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain JHD PF17811.1 EEQ40232.1 - 3.4e-07 30.7 0.1 6.1e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 EEQ40232.1 - 1.6e-06 28.5 0.0 3.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 EEQ40232.1 - 1.6e-06 27.9 10.4 2.9e-06 27.1 10.4 1.4 1 0 0 1 1 1 1 PHD-finger Cupin_1 PF00190.22 EEQ40232.1 - 0.0019 17.8 0.0 0.0041 16.7 0.0 1.5 1 0 0 1 1 1 1 Cupin Cupin_4 PF08007.12 EEQ40232.1 - 0.0087 15.6 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Cupin superfamily protein PHD_Oberon PF07227.11 EEQ40232.1 - 0.032 14.1 7.6 0.07 13.0 7.6 1.5 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein Cupin_2 PF07883.11 EEQ40232.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Cupin domain C1_2 PF03107.16 EEQ40232.1 - 0.76 10.1 9.3 0.58 10.5 4.6 2.6 2 0 0 2 2 2 0 C1 domain C1_1 PF00130.22 EEQ40232.1 - 0.89 9.5 10.1 0.055 13.4 4.0 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 EEQ40232.1 - 3.3 7.8 8.6 60 3.7 8.4 2.2 1 1 1 2 2 2 0 zinc-ribbons DZR PF12773.7 EEQ40232.1 - 9.8 6.3 7.2 80 3.4 7.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon ArAE_2_N PF10337.9 EEQ40233.1 - 2.4e-113 379.7 1.9 3.6e-113 379.1 1.9 1.2 1 0 0 1 1 1 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EEQ40233.1 - 3.4e-08 33.7 10.0 3.4e-08 33.7 10.0 3.2 3 2 0 3 3 3 1 Fusaric acid resistance protein-like Arginosuc_synth PF00764.19 EEQ40234.1 - 4.7e-158 526.5 0.0 5.4e-158 526.3 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EEQ40234.1 - 3.3e-05 23.5 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EEQ40234.1 - 0.00076 18.4 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 EEQ40234.1 - 0.22 11.1 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase Oxidored_FMN PF00724.20 EEQ40235.1 - 3.2e-96 322.6 0.0 3.7e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Vhr1 PF04001.13 EEQ40236.1 - 1.5e-44 150.1 3.5 3.4e-44 149.1 2.5 2.1 2 0 0 2 2 2 1 Transcription factor Vhr1 Y_phosphatase2 PF03162.13 EEQ40237.1 - 4e-41 140.3 0.8 3.9e-25 88.3 0.3 2.2 1 1 1 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EEQ40237.1 - 1.1e-05 25.5 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family SR-25 PF10500.9 EEQ40237.1 - 0.0083 15.8 7.0 0.011 15.3 7.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Pex24p PF06398.11 EEQ40237.1 - 0.011 14.8 0.5 0.014 14.4 0.5 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Med19 PF10278.9 EEQ40237.1 - 0.15 12.0 18.6 0.24 11.3 18.6 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 FCD PF07729.12 EEQ40237.1 - 0.19 12.1 0.2 0.27 11.6 0.2 1.2 1 0 0 1 1 1 0 FCD domain RRN3 PF05327.11 EEQ40237.1 - 0.3 9.6 4.3 0.39 9.2 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Peptidase_S49_N PF08496.10 EEQ40237.1 - 8.5 6.4 8.9 13 5.8 8.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HAGH_C PF16123.5 EEQ40238.1 - 4.5e-21 75.1 0.2 9.2e-21 74.2 0.2 1.5 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EEQ40238.1 - 2.4e-16 60.3 0.9 5.4e-15 55.9 0.9 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EEQ40238.1 - 0.0043 16.6 0.2 0.008 15.7 0.2 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_63 PF03200.16 EEQ40239.1 - 6.8e-173 575.9 0.2 5.8e-172 572.9 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EEQ40239.1 - 1.9e-65 221.1 0.0 3e-65 220.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EEQ40239.1 - 0.036 12.9 0.4 0.18 10.6 0.1 2.0 2 0 0 2 2 2 0 Trehalase CLTH PF10607.9 EEQ40240.1 - 5.4e-31 107.5 1.3 5.4e-31 107.5 1.3 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EEQ40240.1 - 5.8e-09 35.6 0.1 1.3e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 LisH BACK PF07707.15 EEQ40240.1 - 0.0061 16.6 0.5 0.027 14.6 0.4 2.2 2 0 0 2 2 2 1 BTB And C-terminal Kelch Pro_sub2 PF18513.1 EEQ40240.1 - 0.1 12.7 0.4 0.32 11.2 0.4 1.9 1 1 0 1 1 1 0 Prodomain subtilisin 2 AA_synth PF06684.11 EEQ40240.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Amino acid synthesis DCA16 PF15349.6 EEQ40241.1 - 0.075 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 LAMTOR PF15454.6 EEQ40242.1 - 9.3e-10 39.0 1.6 9.3e-10 39.0 1.6 2.3 2 1 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DHODB_Fe-S_bind PF10418.9 EEQ40242.1 - 0.15 11.9 0.0 0.47 10.3 0.0 1.9 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B SRP1_TIP1 PF00660.17 EEQ40242.1 - 0.17 12.0 0.5 0.4 10.8 0.1 1.8 2 0 0 2 2 2 0 Seripauperin and TIP1 family Hydin_ADK PF17213.3 EEQ40242.1 - 0.35 11.1 3.3 0.28 11.5 0.9 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain SR-25 PF10500.9 EEQ40242.1 - 1.9 8.0 14.8 0.21 11.2 10.7 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.10 EEQ40242.1 - 2.5 8.2 8.9 1.9 8.6 6.4 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CTU2 PF10288.9 EEQ40242.1 - 2.5 8.4 9.8 46 4.3 8.1 2.3 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 LRR_8 PF13855.6 EEQ40243.1 - 3e-15 55.7 35.3 1.1e-07 31.5 8.9 5.3 3 1 4 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 EEQ40243.1 - 4.8e-09 36.3 32.6 0.00065 20.0 4.7 6.1 5 2 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EEQ40243.1 - 3.4e-06 26.7 25.0 0.00038 20.3 1.5 6.7 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 EEQ40243.1 - 7.7e-05 22.7 28.1 1 10.2 0.4 7.9 9 0 0 9 9 9 4 Leucine Rich Repeat DUF4130 PF13566.6 EEQ40243.1 - 0.11 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 FNIP PF05725.12 EEQ40243.1 - 1.5 9.1 14.7 1.2 9.4 0.8 3.9 5 0 0 5 5 5 0 FNIP Repeat LRR_9 PF14580.6 EEQ40243.1 - 2.6 7.5 7.2 1.4 8.4 1.6 3.0 2 1 2 4 4 4 0 Leucine-rich repeat AMMECR1 PF01871.17 EEQ40244.1 - 3.3e-46 156.9 0.0 4.2e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 AMMECR1 Zip PF02535.22 EEQ40245.1 - 3.4e-38 131.7 5.2 8.4e-38 130.4 5.2 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1774 PF08611.10 EEQ40245.1 - 0.11 12.8 4.7 0.3 11.4 0.0 3.1 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1774) UCH PF00443.29 EEQ40246.1 - 8.2e-52 176.2 0.0 1.6e-51 175.2 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ40246.1 - 7.3e-28 98.1 4.5 3.5e-21 76.1 0.7 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PMSR PF01625.21 EEQ40247.1 - 1.7e-54 184.2 0.2 2e-54 183.9 0.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DNA_pol3_delta2 PF13177.6 EEQ40248.1 - 6.3e-10 39.1 0.1 1.3e-09 38.1 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EEQ40248.1 - 7.4e-07 29.7 0.9 2e-06 28.2 0.4 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEQ40248.1 - 1.7e-06 28.1 0.1 3.2e-06 27.2 0.1 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 EEQ40248.1 - 0.0029 17.9 0.8 0.041 14.1 0.1 2.8 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ40248.1 - 0.032 14.6 0.4 0.11 12.9 0.4 2.2 1 1 0 1 1 1 0 AAA ATPase domain Mg_chelatase PF01078.21 EEQ40248.1 - 0.042 13.2 0.0 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EEQ40248.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EEQ40248.1 - 0.14 12.5 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pmp3 PF01679.17 EEQ40249.1 - 1.5e-09 37.9 7.1 2.2e-09 37.4 7.1 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Tmemb_55A PF09788.9 EEQ40249.1 - 1.6 7.7 4.3 1.2 8.2 0.3 1.9 2 0 0 2 2 2 0 Transmembrane protein 55A Snf7 PF03357.21 EEQ40250.1 - 2.6e-20 72.7 17.5 2.8e-20 72.6 17.1 1.3 1 1 0 1 1 1 1 Snf7 APH_6_hur PF04655.14 EEQ40250.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase ZIP4_domain PF18292.1 EEQ40250.1 - 0.089 12.7 1.5 0.12 12.3 0.4 1.7 1 1 1 2 2 2 0 Zinc transporter ZIP4 domain DDE_Tnp_ISL3 PF01610.17 EEQ40250.1 - 1.8 8.2 7.9 2.6 7.7 5.7 1.9 1 1 1 2 2 2 0 Transposase DegS PF05384.11 EEQ40250.1 - 4.7 6.7 15.8 1.7 8.1 3.8 3.1 2 1 1 3 3 3 0 Sensor protein DegS Cwf_Cwc_15 PF04889.12 EEQ40251.1 - 0.0016 18.3 7.0 0.0016 18.3 7.0 1.6 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 EEQ40251.1 - 0.0036 17.5 5.0 0.0047 17.1 5.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 EEQ40251.1 - 0.015 13.6 4.3 0.017 13.4 4.3 1.0 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 EEQ40251.1 - 0.04 14.3 16.0 0.066 13.6 16.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.10 EEQ40251.1 - 0.043 13.2 8.6 0.051 12.9 8.6 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EEQ40251.1 - 0.068 12.6 6.4 0.087 12.2 6.4 1.1 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 EEQ40251.1 - 0.17 11.8 2.7 0.22 11.4 2.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.11 EEQ40251.1 - 0.22 11.5 8.2 0.15 12.1 5.4 1.8 1 1 1 2 2 2 0 RXT2-like, N-terminal Mucin PF01456.17 EEQ40251.1 - 0.3 11.1 14.4 0.18 11.8 11.1 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein NOA36 PF06524.12 EEQ40251.1 - 0.5 9.7 9.5 0.7 9.1 9.5 1.2 1 0 0 1 1 1 0 NOA36 protein eIF-3c_N PF05470.12 EEQ40251.1 - 0.5 8.6 2.3 0.61 8.3 2.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC45 PF02724.14 EEQ40251.1 - 0.53 8.5 5.0 0.64 8.2 5.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EEQ40251.1 - 0.6 8.1 12.4 0.81 7.7 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi SGT1 PF07093.11 EEQ40251.1 - 0.7 8.3 2.6 0.85 8.0 2.6 1.1 1 0 0 1 1 1 0 SGT1 protein RRN3 PF05327.11 EEQ40251.1 - 2.1 6.8 3.6 2.2 6.7 3.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EEQ40253.1 - 0.66 8.0 13.0 0.95 7.5 13.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EEQ40253.1 - 3.6 6.8 11.8 5 6.4 11.8 1.2 1 0 0 1 1 1 0 BUD22 BLOC1_2 PF10046.9 EEQ40254.1 - 6.3e-20 71.3 5.1 8.2e-20 70.9 5.1 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4763 PF15960.5 EEQ40254.1 - 0.0031 16.9 1.9 0.0042 16.4 1.7 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4763) Spc7 PF08317.11 EEQ40254.1 - 0.055 12.4 5.7 0.067 12.1 5.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF484 PF04340.12 EEQ40254.1 - 0.061 13.0 2.3 0.086 12.5 1.6 1.5 1 1 1 2 2 2 0 Protein of unknown function, DUF484 AAA_23 PF13476.6 EEQ40254.1 - 0.069 13.6 2.6 0.078 13.5 2.6 1.0 1 0 0 1 1 1 0 AAA domain DUF1664 PF07889.12 EEQ40254.1 - 0.077 13.0 0.8 0.11 12.6 0.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF5320 PF17253.2 EEQ40254.1 - 0.63 11.1 1.4 0.95 10.6 1.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Ribosomal_L16 PF00252.18 EEQ40255.1 - 9.8e-33 113.0 0.4 1.4e-32 112.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.20 EEQ40256.1 - 2e-52 178.1 0.6 1.2e-26 93.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EEQ40256.1 - 1.1e-23 83.4 0.0 2.9e-23 82.1 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.20 EEQ40256.1 - 0.031 13.4 0.7 2.8 6.9 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) Flavodoxin_1 PF00258.25 EEQ40257.1 - 1.5e-30 106.3 0.0 2.8e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EEQ40257.1 - 1.8e-23 83.3 0.0 2.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EEQ40257.1 - 1e-10 42.2 0.0 2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 EEQ40257.1 - 0.018 14.7 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain Flavodoxin_5 PF12724.7 EEQ40257.1 - 0.19 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain Bromodomain PF00439.25 EEQ40258.1 - 2.6e-33 113.9 0.3 9.1e-18 64.1 0.1 2.5 2 0 0 2 2 2 2 Bromodomain MnmE_helical PF12631.7 EEQ40259.1 - 1.2e-42 146.4 0.2 1.5e-42 146.1 0.2 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EEQ40259.1 - 6.8e-35 119.9 0.0 3.7e-34 117.5 0.0 2.0 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EEQ40259.1 - 7.7e-21 74.3 0.1 3e-20 72.4 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ40259.1 - 3.5e-10 39.6 0.1 6.4e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEQ40259.1 - 2.7e-08 33.9 0.3 0.0086 16.0 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EEQ40259.1 - 1.8e-07 30.9 0.5 8.9e-06 25.4 0.3 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EEQ40259.1 - 3.5e-05 23.9 0.2 0.0099 15.9 0.0 2.7 2 1 1 3 3 2 1 Dynamin family AAA_16 PF13191.6 EEQ40259.1 - 0.00038 20.9 0.1 0.0013 19.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain Arf PF00025.21 EEQ40259.1 - 0.00061 19.3 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1_Xtn PF16897.5 EEQ40259.1 - 0.0012 18.8 0.1 0.0056 16.7 0.0 2.2 1 1 1 2 2 2 1 C-terminal region of MMR_HSR1 domain Phage_CII PF05269.11 EEQ40259.1 - 0.0045 17.2 0.2 0.14 12.3 0.0 3.0 3 0 0 3 3 3 1 Bacteriophage CII protein cobW PF02492.19 EEQ40259.1 - 0.016 14.8 0.3 0.9 9.1 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EEQ40259.1 - 0.024 14.8 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EEQ40259.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ40259.1 - 0.028 14.9 0.0 0.061 13.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EEQ40259.1 - 0.076 13.6 0.0 0.28 11.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain Mon2_C PF16206.5 EEQ40259.1 - 0.094 10.8 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 C-terminal region of Mon2 protein ATP-synt_F PF01990.17 EEQ40259.1 - 0.12 12.7 0.1 1 9.8 0.0 2.5 3 0 0 3 3 3 0 ATP synthase (F/14-kDa) subunit AAA_24 PF13479.6 EEQ40259.1 - 0.17 11.6 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 EEQ40260.1 - 1.9e-95 319.0 0.2 2.1e-95 318.8 0.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EEQ40260.1 - 2.3e-09 37.4 0.0 3.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EEQ40260.1 - 4.4e-07 30.0 1.9 1.2e-05 25.3 0.6 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EEQ40260.1 - 3.5e-05 23.2 0.0 5.5e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EEQ40260.1 - 0.0001 21.6 3.0 0.00023 20.5 1.6 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.18 EEQ40260.1 - 0.0002 20.9 0.1 0.35 10.3 0.1 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EEQ40260.1 - 0.0054 16.6 1.5 0.042 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain PhnA_Zn_Ribbon PF08274.12 EEQ40260.1 - 0.035 14.0 0.3 0.068 13.1 0.3 1.4 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF1610 PF07754.11 EEQ40260.1 - 0.042 13.8 1.9 0.67 10.0 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Zn_Tnp_IS1595 PF12760.7 EEQ40260.1 - 0.094 12.7 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Oest_recep PF02159.15 EEQ40261.1 - 0.49 10.9 3.8 0.23 11.9 1.2 1.7 2 1 0 2 2 2 0 Oestrogen receptor CTP_transf_1 PF01148.20 EEQ40262.1 - 5e-05 23.2 2.3 7.4e-05 22.6 2.3 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family ABC_membrane PF00664.23 EEQ40263.1 - 2.3e-62 211.1 42.8 5.4e-42 144.3 21.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EEQ40263.1 - 6.2e-47 159.6 0.6 4.9e-29 101.6 0.0 3.5 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EEQ40263.1 - 2.2e-09 37.1 5.4 0.00037 20.0 0.3 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EEQ40263.1 - 3.1e-09 37.0 0.1 0.0065 16.2 0.0 3.6 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 EEQ40263.1 - 7.4e-07 28.8 0.5 0.013 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EEQ40263.1 - 6.9e-05 22.8 9.4 0.61 9.8 0.1 4.9 5 1 1 6 6 6 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EEQ40263.1 - 0.00021 21.2 0.6 0.38 10.6 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEQ40263.1 - 0.00052 20.1 3.1 0.43 10.7 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EEQ40263.1 - 0.00054 20.4 0.0 0.14 12.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EEQ40263.1 - 0.0036 17.0 0.9 1.3 8.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EEQ40263.1 - 0.0086 15.4 0.1 4.1 6.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Voldacs PF03517.13 EEQ40263.1 - 0.014 15.5 0.3 0.055 13.6 0.3 2.1 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling AAA_18 PF13238.6 EEQ40263.1 - 0.028 15.0 5.9 1.8 9.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EEQ40263.1 - 0.028 14.1 0.0 11 5.7 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SSE PF00437.20 EEQ40263.1 - 0.029 13.4 0.1 0.56 9.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EEQ40263.1 - 0.03 14.6 3.5 5.2 7.3 0.1 3.3 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EEQ40263.1 - 0.03 13.9 2.2 0.08 12.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EEQ40263.1 - 0.033 14.7 21.6 0.31 11.5 0.1 3.9 3 1 0 3 3 2 0 AAA domain AAA PF00004.29 EEQ40263.1 - 0.037 14.4 1.1 3 8.3 0.0 3.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 EEQ40263.1 - 0.14 11.9 1.2 32 4.2 0.1 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 EEQ40263.1 - 0.16 11.1 0.5 17 4.5 0.0 2.8 3 0 0 3 3 2 0 NB-ARC domain MeaB PF03308.16 EEQ40263.1 - 0.19 10.7 0.3 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TsaE PF02367.17 EEQ40263.1 - 0.2 11.7 0.8 5.2 7.1 0.0 3.0 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EEQ40263.1 - 0.39 10.6 0.0 0.39 10.6 0.0 3.3 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea Vps51 PF08700.11 EEQ40263.1 - 0.71 10.0 6.1 0.23 11.6 0.3 3.0 3 0 0 3 3 3 0 Vps51/Vps67 PHD PF00628.29 EEQ40264.1 - 1.7e-06 27.8 11.9 3.6e-06 26.8 11.9 1.6 1 0 0 1 1 1 1 PHD-finger Pam16 PF03656.13 EEQ40265.1 - 2e-33 115.1 1.5 2.3e-33 114.9 1.5 1.0 1 0 0 1 1 1 1 Pam16 IBR PF01485.21 EEQ40267.1 - 4.5e-15 55.6 37.5 9.8e-09 35.3 1.7 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EEQ40267.1 - 0.00013 21.7 8.2 0.00013 21.7 8.2 5.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) DUF3348 PF11828.8 EEQ40267.1 - 0.17 11.5 0.6 0.26 10.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) UNC-50 PF05216.13 EEQ40271.1 - 6.1e-89 297.4 17.8 7e-89 297.2 17.8 1.0 1 0 0 1 1 1 1 UNC-50 family DUF3808 PF10300.9 EEQ40272.1 - 1e-123 413.6 2.6 1.3e-123 413.2 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 EEQ40272.1 - 0.00019 21.5 0.9 0.61 10.3 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat DUF3848 PF12959.7 EEQ40272.1 - 0.026 14.6 0.8 0.36 10.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) DUF3877 PF12993.7 EEQ40272.1 - 0.042 13.7 0.2 0.51 10.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) CAP PF00188.26 EEQ40273.1 - 9e-17 62.1 5.4 9e-17 62.1 5.4 2.2 2 2 0 2 2 2 1 Cysteine-rich secretory protein family Hamartin PF04388.12 EEQ40273.1 - 1.6 7.3 18.4 1.9 7.1 18.4 1.0 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 EEQ40273.1 - 5 6.2 27.6 6.3 5.9 27.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Ribosomal_L4 PF00573.22 EEQ40274.1 - 3e-42 144.5 2.9 4.7e-42 143.8 2.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EEQ40274.1 - 1.6e-29 101.8 4.7 4e-28 97.3 2.3 2.5 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain Pro_isomerase PF00160.21 EEQ40275.1 - 5.4e-38 130.8 0.0 7.8e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 EEQ40275.1 - 4.3e-09 35.8 6.9 5.6e-06 26.0 0.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ40275.1 - 9.5e-09 34.7 7.6 2.4e-05 24.1 0.9 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ40275.1 - 6.9e-06 25.7 0.1 0.0018 18.2 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ40275.1 - 3.9e-05 23.5 6.5 0.00016 21.6 1.4 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ40275.1 - 7.6e-05 22.9 0.6 0.0044 17.3 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Paf67 PF10255.9 EEQ40275.1 - 0.027 13.5 0.3 0.036 13.0 0.3 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TPR_10 PF13374.6 EEQ40275.1 - 0.037 13.9 0.9 0.36 10.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ40275.1 - 0.1 12.3 4.9 2.4 7.9 0.0 3.5 2 2 2 4 4 4 0 TPR repeat TPR_6 PF13174.6 EEQ40275.1 - 0.1 13.3 5.3 0.66 10.7 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EEQ40275.1 - 0.43 10.7 6.5 0.26 11.4 0.5 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain SQS_PSY PF00494.19 EEQ40276.1 - 2e-27 96.4 0.1 4e-27 95.4 0.1 1.4 1 1 0 1 1 1 1 Squalene/phytoene synthase Sec7 PF01369.20 EEQ40277.1 - 9.6e-67 224.2 0.1 2.7e-66 222.8 0.1 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EEQ40277.1 - 1.4e-13 51.0 0.6 1.4e-13 51.0 0.6 3.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EEQ40277.1 - 7.2e-09 35.6 2.6 4.7e-08 32.9 2.6 2.5 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF3361 PF11841.8 EEQ40277.1 - 0.046 13.7 0.5 0.73 9.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) DUF3427 PF11907.8 EEQ40277.1 - 0.17 11.1 2.3 0.47 9.7 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3427) Poxvirus PF06227.12 EEQ40277.1 - 1.2 8.8 5.6 0.31 10.8 0.8 2.5 2 0 0 2 2 2 0 dsDNA Poxvirus OMPdecase PF00215.24 EEQ40278.1 - 5.9e-78 261.5 0.1 6.9e-78 261.3 0.1 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Glyco_hydro_3_C PF01915.22 EEQ40278.1 - 0.09 12.7 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Mito_carr PF00153.27 EEQ40279.1 - 1.2e-11 44.4 1.1 7.6e-07 29.0 0.1 3.2 3 0 0 3 3 3 2 Mitochondrial carrier protein Vps26 PF03643.15 EEQ40280.1 - 1.1e-112 375.5 0.0 1.3e-112 375.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EEQ40280.1 - 7.9e-08 32.5 0.6 0.0098 16.0 0.1 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 EEQ40280.1 - 0.091 11.9 0.2 8.3 5.5 0.0 2.8 3 0 0 3 3 3 0 Rgp1 Gp_dh_C PF02800.20 EEQ40282.1 - 4.3e-62 208.4 0.1 5e-62 208.2 0.1 1.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Goodbye PF17109.5 EEQ40283.1 - 0.015 15.7 0.1 0.023 15.1 0.1 1.2 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain RasGEF PF00617.19 EEQ40284.1 - 4.1e-56 190.0 2.4 6.6e-56 189.3 1.3 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EEQ40284.1 - 2.3e-22 79.2 0.7 8.2e-22 77.4 0.7 2.0 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EEQ40284.1 - 4.6e-11 42.2 0.0 8.8e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EEQ40284.1 - 3.7e-09 36.3 0.1 8.7e-09 35.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EEQ40284.1 - 5.6e-06 26.0 0.0 1.3e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain GRIP PF01465.20 EEQ40285.1 - 1e-12 47.7 0.0 3.5e-12 46.0 0.0 2.1 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.9 EEQ40285.1 - 7e-06 26.1 251.5 7.6e-06 26.0 24.3 12.4 1 1 9 11 11 11 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.12 EEQ40285.1 - 0.00033 20.7 11.2 0.00033 20.7 11.2 12.9 2 2 7 11 11 11 4 TPR/MLP1/MLP2-like protein Filament PF00038.21 EEQ40285.1 - 0.00033 20.3 34.2 0.00033 20.3 34.2 8.2 1 1 5 6 6 6 1 Intermediate filament protein DUF1664 PF07889.12 EEQ40285.1 - 0.0057 16.7 8.4 0.0057 16.7 8.4 12.0 3 2 7 13 13 13 7 Protein of unknown function (DUF1664) CcdB PF01845.17 EEQ40285.1 - 2.6 8.3 10.0 11 6.3 0.2 5.2 4 0 0 4 4 4 0 CcdB protein Spc7 PF08317.11 EEQ40285.1 - 6.6 5.5 238.6 0.013 14.4 30.5 10.6 1 1 10 11 11 11 0 Spc7 kinetochore protein TYW3 PF02676.14 EEQ40286.1 - 1.2e-65 220.9 0.0 1.8e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 zf-RING_2 PF13639.6 EEQ40287.1 - 6.3e-10 39.2 7.0 1e-08 35.3 3.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EEQ40287.1 - 1.8e-07 31.3 4.7 3.9e-07 30.3 1.8 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EEQ40287.1 - 3.9e-07 29.8 7.9 5e-06 26.3 4.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ40287.1 - 1.3e-06 28.3 5.3 7.2e-05 22.7 2.0 2.6 2 1 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EEQ40287.1 - 1.8e-05 24.5 3.6 5.5e-05 22.9 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ40287.1 - 5.7e-05 22.9 5.8 0.00076 19.3 2.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ40287.1 - 9.2e-05 22.2 2.3 9.2e-05 22.2 2.3 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ40287.1 - 0.0012 18.8 4.9 0.007 16.3 1.8 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EEQ40287.1 - 0.0037 17.3 0.9 0.063 13.3 0.6 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EEQ40287.1 - 0.0088 16.2 3.3 0.0088 16.2 3.3 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EEQ40287.1 - 0.055 13.2 2.2 4.2 7.2 0.4 2.4 2 0 0 2 2 2 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EEQ40287.1 - 0.077 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type LRIF1 PF15741.5 EEQ40287.1 - 1.2 7.6 14.6 0.045 12.3 2.1 2.2 2 0 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 RINGv PF12906.7 EEQ40287.1 - 1.6 8.9 4.3 1.5 9.0 1.6 2.1 2 0 0 2 2 2 0 RING-variant domain Complex1_30kDa PF00329.19 EEQ40288.1 - 8.4e-47 158.8 0.0 1.3e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit End3 PF12761.7 EEQ40289.1 - 3.6e-62 210.1 1.3 5e-62 209.6 1.3 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EEQ40289.1 - 7.9e-56 186.4 0.1 1.2e-54 182.7 0.1 2.3 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EEQ40289.1 - 3.1e-06 26.3 1.1 9.6e-06 24.8 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EEQ40289.1 - 4.9e-05 23.7 0.0 0.00035 21.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EEQ40289.1 - 0.0025 17.6 1.5 0.0066 16.3 0.2 2.5 3 0 0 3 3 2 1 EF-hand domain EF-hand_8 PF13833.6 EEQ40289.1 - 0.0069 16.2 0.0 0.017 15.0 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EEQ40289.1 - 0.059 12.9 2.0 0.17 11.5 0.2 2.6 2 0 0 2 2 2 0 EF hand TACC_C PF05010.14 EEQ40289.1 - 0.096 12.5 3.7 0.1 12.4 2.6 1.5 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PP_kinase_N PF13089.6 EEQ40289.1 - 0.13 12.6 0.6 0.57 10.5 0.0 2.2 2 1 0 2 2 2 0 Polyphosphate kinase N-terminal domain APG6_N PF17675.1 EEQ40289.1 - 0.82 10.2 7.5 1.6 9.3 7.5 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region FlxA PF14282.6 EEQ40289.1 - 1.2 9.2 4.3 11 6.1 4.8 2.1 1 1 1 2 2 2 0 FlxA-like protein FUSC PF04632.12 EEQ40289.1 - 3.6 6.0 7.6 4.5 5.7 7.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family WD40 PF00400.32 EEQ40290.1 - 5.8e-08 33.3 13.5 0.016 16.1 0.4 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 EEQ40290.1 - 0.00054 18.7 0.2 0.0019 16.9 0.2 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEQ40290.1 - 0.00055 20.2 0.3 0.21 11.9 0.2 2.8 1 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EEQ40290.1 - 0.0087 16.5 0.1 0.086 13.4 0.0 2.6 2 0 0 2 2 2 1 PQQ-like domain DUF4398 PF14346.6 EEQ40290.1 - 1 10.0 11.0 0.13 12.9 2.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) NMT_C PF02799.15 EEQ40292.1 - 9.1e-79 263.8 0.0 1.3e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EEQ40292.1 - 1.1e-75 252.9 0.0 2e-75 252.0 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EEQ40292.1 - 0.0032 17.6 0.0 0.12 12.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ40292.1 - 0.0093 16.2 0.0 0.019 15.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family F-box-like PF12937.7 EEQ40293.1 - 8.7e-05 22.3 0.8 0.00015 21.6 0.8 1.4 1 0 0 1 1 1 1 F-box-like MIT PF04212.18 EEQ40293.1 - 0.0089 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain eIF-3c_N PF05470.12 EEQ40294.1 - 1e-134 450.1 2.0 5.9e-107 358.4 0.1 3.1 3 1 1 4 4 4 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EEQ40294.1 - 1.7e-06 28.5 0.0 7.4e-06 26.4 0.0 2.2 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 EEQ40294.1 - 0.082 13.8 0.6 21 6.3 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypan_glycop PF00913.19 EEQ40294.1 - 0.43 9.8 9.5 0.57 9.4 0.0 3.1 3 0 0 3 3 3 0 Trypanosome variant surface glycoprotein (A-type) zn-ribbon_14 PF16503.5 EEQ40295.1 - 2.6e-16 58.8 3.2 2.6e-16 58.8 3.2 3.1 3 1 1 4 4 4 1 Zinc-ribbon ATP_bind_3 PF01171.20 EEQ40295.1 - 1.7e-10 40.9 0.0 2.7e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 EEQ40295.1 - 3.6 7.2 9.9 0.4 10.3 4.5 2.0 2 0 0 2 2 2 0 RecR protein CBM_21 PF03370.13 EEQ40296.1 - 2.4e-21 76.0 1.3 2.4e-21 76.0 1.3 2.0 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EEQ40296.1 - 6e-08 33.2 1.1 1.7e-07 31.7 1.1 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) tRNA-synt_1c PF00749.21 EEQ40297.1 - 3.5e-112 374.4 0.0 5.2e-112 373.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 EEQ40297.1 - 7.3e-47 159.4 1.0 1.2e-46 158.6 1.0 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 EEQ40297.1 - 1.1e-32 113.2 1.7 4.8e-31 108.0 0.1 2.9 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 EEQ40297.1 - 3.6e-10 40.6 3.6 1.3e-09 38.9 3.6 2.0 1 1 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 EstA_Ig_like PF18435.1 EEQ40297.1 - 0.071 13.3 0.3 0.17 12.1 0.3 1.6 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain Abhydrolase_1 PF00561.20 EEQ40298.1 - 7e-18 65.2 0.0 4.4e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ40298.1 - 6.1e-13 48.6 0.0 1.3e-10 41.0 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EEQ40298.1 - 5.2e-12 46.8 0.0 1.3e-11 45.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EEQ40298.1 - 0.00074 18.9 0.0 0.0023 17.3 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_3 PF07859.13 EEQ40298.1 - 0.0046 16.8 0.0 0.009 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EEQ40298.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 EEQ40298.1 - 0.069 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Sulfatase PF00884.23 EEQ40299.1 - 1.2e-73 248.2 0.1 1.6e-73 247.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EEQ40299.1 - 0.00014 21.6 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EEQ40299.1 - 0.0014 19.4 0.1 0.082 13.7 0.1 2.5 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 EEQ40299.1 - 0.0016 17.1 0.0 0.0022 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF4994 PF16385.5 EEQ40299.1 - 0.0037 17.2 0.0 0.072 13.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF4976 PF16347.5 EEQ40299.1 - 0.091 13.0 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Plus-3 PF03126.18 EEQ40300.1 - 9.4e-26 90.5 0.1 2.6e-25 89.1 0.1 1.8 1 0 0 1 1 1 1 Plus-3 domain DUF2701 PF10857.8 EEQ40301.1 - 0.06 13.4 0.2 0.77 9.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) DUF2781 PF10914.8 EEQ40302.1 - 1.4e-44 152.1 4.4 1.6e-44 151.9 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) RNase_T PF00929.24 EEQ40303.1 - 2.3e-32 112.8 0.0 2.3e-32 112.8 0.0 1.4 2 0 0 2 2 2 1 Exonuclease Pkinase PF00069.25 EEQ40304.1 - 9.9e-64 215.2 0.0 1.1e-39 136.5 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40304.1 - 1e-29 103.6 0.1 2.3e-22 79.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EEQ40304.1 - 2.4e-09 37.3 0.0 5.7e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EEQ40304.1 - 0.00052 19.4 0.0 0.0017 17.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EEQ40304.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ40304.1 - 0.0021 17.4 0.0 0.0042 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EEQ40304.1 - 0.019 13.9 3.8 0.026 13.5 0.0 2.7 2 1 0 2 2 2 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 EEQ40304.1 - 0.038 13.1 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 PAS_9 PF13426.7 EEQ40304.1 - 0.098 12.9 0.1 0.51 10.6 0.0 2.3 3 0 0 3 3 3 0 PAS domain RIO1 PF01163.22 EEQ40304.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family bZIP_2 PF07716.15 EEQ40305.1 - 1.2e-09 38.1 12.0 1.2e-09 38.1 12.0 2.0 2 0 0 2 2 2 1 Basic region leucine zipper DUF4094 PF13334.6 EEQ40305.1 - 0.0099 16.3 1.1 0.019 15.3 1.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) YabA PF06156.13 EEQ40305.1 - 0.023 15.3 4.7 0.042 14.5 4.7 1.4 1 0 0 1 1 1 0 Initiation control protein YabA DUF3450 PF11932.8 EEQ40305.1 - 0.088 12.1 4.5 0.12 11.7 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 EEQ40305.1 - 0.17 11.7 7.8 0.24 11.2 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 EEQ40305.1 - 0.43 11.2 7.1 1.6 9.3 6.9 1.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal bZIP_1 PF00170.21 EEQ40305.1 - 0.92 9.7 19.3 2.2 8.4 19.3 1.7 1 1 0 1 1 1 0 bZIP transcription factor PSP1 PF04468.12 EEQ40307.1 - 3.4e-33 113.8 3.0 6.7e-33 112.8 3.0 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region SRF-TF PF00319.18 EEQ40308.1 - 4e-21 74.2 0.1 5.8e-21 73.7 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Synaphin PF05835.12 EEQ40308.1 - 0.07 13.4 0.4 0.07 13.4 0.4 2.1 2 1 0 2 2 2 0 Synaphin protein Pex14_N PF04695.13 EEQ40308.1 - 0.72 10.5 10.5 1.2 9.8 10.5 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PWWP PF00855.17 EEQ40309.1 - 6.3e-20 71.4 0.1 2.4e-19 69.5 0.1 2.1 1 0 0 1 1 1 1 PWWP domain PQQ_3 PF13570.6 EEQ40312.1 - 0.72 10.4 3.9 0.68 10.5 0.5 2.9 2 1 0 2 2 2 0 PQQ-like domain WD40 PF00400.32 EEQ40312.1 - 0.87 10.6 3.7 2.9 8.9 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Phosphorylase PF00343.20 EEQ40313.1 - 0 1023.6 0.0 0 1023.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Peptidase_S10 PF00450.22 EEQ40314.1 - 2e-106 356.9 0.3 2.9e-106 356.4 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase AF-4 PF05110.13 EEQ40314.1 - 2.6 6.0 9.2 3.7 5.5 9.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Ribosomal_L4 PF00573.22 EEQ40315.1 - 2.5e-44 151.3 0.0 2.9e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S13 PF00416.22 EEQ40316.1 - 1.4e-51 174.2 1.0 1.6e-51 174.0 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EEQ40316.1 - 0.0067 15.2 0.0 0.0073 15.1 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3196 PF11428.8 EEQ40316.1 - 0.03 13.9 0.0 0.036 13.6 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3196) DUF2746 PF10874.8 EEQ40316.1 - 0.048 14.1 0.0 0.069 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) SNF2_N PF00176.23 EEQ40317.1 - 2.1e-53 181.3 0.0 6.6e-53 179.7 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ40317.1 - 1.2e-15 57.9 0.0 5.8e-15 55.6 0.0 2.2 3 0 0 3 3 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ40317.1 - 3e-08 33.8 0.0 8.3e-08 32.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EEQ40317.1 - 8e-08 32.0 13.0 8e-08 32.0 13.0 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EEQ40317.1 - 3.2e-05 23.8 0.0 6.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 EEQ40317.1 - 5.3e-05 23.0 12.0 5.3e-05 23.0 12.0 2.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EEQ40317.1 - 0.00075 19.6 12.4 0.00075 19.6 12.4 2.7 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING Shugoshin_C PF07557.11 EEQ40317.1 - 0.0025 17.6 3.9 0.0025 17.6 3.9 2.1 2 0 0 2 2 2 1 Shugoshin C terminus zf-C3HC4_3 PF13920.6 EEQ40317.1 - 0.014 15.2 11.0 0.014 15.2 11.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ40317.1 - 0.017 15.1 8.5 0.017 15.1 8.5 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 EEQ40317.1 - 0.021 15.1 13.1 0.021 15.1 13.1 2.3 2 1 1 3 3 2 0 Ring finger domain zf-rbx1 PF12678.7 EEQ40317.1 - 0.044 14.1 7.5 0.13 12.5 7.5 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain tRNA-synt_1b PF00579.25 EEQ40317.1 - 0.13 11.5 1.7 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) zf-RING_10 PF16685.5 EEQ40317.1 - 0.16 12.1 5.8 1.1 9.4 6.0 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 NAD_binding_4 PF07993.12 EEQ40318.1 - 3.4e-72 242.7 0.0 4.9e-72 242.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EEQ40318.1 - 2.5e-64 217.5 0.0 3.5e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 EEQ40318.1 - 8.9e-13 48.4 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EEQ40318.1 - 6e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ40318.1 - 1.4e-06 27.5 0.0 6.9e-06 25.3 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EEQ40318.1 - 0.00011 23.1 0.0 0.00044 21.2 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 EEQ40318.1 - 0.0004 19.9 0.0 0.00084 18.8 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EEQ40318.1 - 0.00041 19.6 0.0 0.0018 17.5 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Condensation PF00668.20 EEQ40318.1 - 0.002 16.9 0.1 0.41 9.3 0.5 2.3 2 0 0 2 2 2 2 Condensation domain NAD_binding_10 PF13460.6 EEQ40318.1 - 0.018 15.0 0.1 0.13 12.2 0.1 2.4 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 EEQ40318.1 - 0.059 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family UN_NPL4 PF11543.8 EEQ40318.1 - 0.2 12.2 0.1 17 6.0 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 Hph PF13694.6 EEQ40319.1 - 0.0055 17.0 0.2 0.0055 17.0 0.2 1.7 2 0 0 2 2 2 1 Sec63/Sec62 complex-interacting family Ribosomal_L50 PF10501.9 EEQ40319.1 - 0.028 14.5 0.4 0.062 13.5 0.4 1.6 1 0 0 1 1 1 0 Ribosomal subunit 39S Exonuc_VII_L PF02601.15 EEQ40319.1 - 0.067 12.7 6.1 0.088 12.4 6.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 EEQ40319.1 - 0.37 10.0 3.0 0.52 9.5 3.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein KfrA_N PF11740.8 EEQ40319.1 - 1.8 9.3 7.2 1.7 9.3 3.6 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term PDEase_I PF00233.19 EEQ40320.1 - 1.3e-52 178.9 1.3 1.2e-45 156.2 0.0 2.4 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase SAM_2 PF07647.17 EEQ40321.1 - 1.3e-07 31.6 0.1 2.7e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EEQ40321.1 - 0.00048 20.5 0.8 0.00094 19.6 0.1 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) IGR PF09597.10 EEQ40321.1 - 0.04 14.0 0.1 0.089 12.9 0.1 1.5 1 0 0 1 1 1 0 IGR protein motif Synaptobrevin PF00957.21 EEQ40322.1 - 1.6e-15 56.6 0.6 2.6e-15 55.9 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EEQ40322.1 - 4e-10 39.6 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Ras PF00071.22 EEQ40323.1 - 5.5e-39 133.4 0.0 1.7e-38 131.8 0.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EEQ40323.1 - 9.2e-29 100.1 0.1 8.4e-28 97.0 0.1 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ40323.1 - 1.9e-09 37.2 0.0 2e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ40323.1 - 2.5e-06 27.0 0.0 7.1e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ40323.1 - 7.9e-06 25.9 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ40323.1 - 0.00019 21.0 0.0 0.00025 20.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EEQ40323.1 - 0.0092 15.9 0.0 0.53 10.2 0.0 2.4 2 1 1 3 3 3 1 RsgA GTPase G-alpha PF00503.20 EEQ40323.1 - 0.037 13.2 0.1 3.2 6.8 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit Sigma54_activat PF00158.26 EEQ40323.1 - 0.071 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DAP3 PF10236.9 EEQ40323.1 - 0.08 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.6 EEQ40323.1 - 0.085 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EEQ40323.1 - 0.11 12.8 0.0 1.1 9.6 0.0 2.2 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 EEQ40323.1 - 0.13 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain CHCH PF06747.13 EEQ40324.1 - 2.2e-08 34.0 3.0 4e-08 33.2 3.0 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EEQ40324.1 - 0.00035 20.9 2.6 0.00035 20.9 2.6 2.0 2 0 0 2 2 2 1 GCK domain MAS20 PF02064.15 EEQ40324.1 - 0.017 15.2 1.0 0.087 12.9 0.1 2.1 2 0 0 2 2 2 0 MAS20 protein import receptor Serinc PF03348.15 EEQ40324.1 - 0.062 12.2 1.7 0.047 12.6 0.4 1.3 2 0 0 2 2 2 0 Serine incorporator (Serinc) Di19_C PF14571.6 EEQ40324.1 - 0.084 13.4 1.1 0.19 12.3 1.1 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal G-patch PF01585.23 EEQ40325.1 - 1.4e-12 47.3 6.7 2.5e-12 46.5 6.7 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEQ40325.1 - 1.5e-06 28.2 1.9 3.1e-06 27.2 1.3 1.9 1 1 0 1 1 1 1 G-patch domain 5_nucleotid PF05761.14 EEQ40325.1 - 0.037 12.9 0.6 0.063 12.2 0.6 1.4 1 0 0 1 1 1 0 5' nucleotidase family FliJ PF02050.16 EEQ40325.1 - 0.041 14.1 2.3 0.057 13.7 0.5 2.2 3 0 0 3 3 3 0 Flagellar FliJ protein TPR_MLP1_2 PF07926.12 EEQ40325.1 - 0.053 13.6 5.2 0.028 14.5 2.2 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DASH_Duo1 PF08651.10 EEQ40325.1 - 0.15 11.9 1.4 1.9 8.3 1.2 2.7 1 1 1 2 2 2 0 DASH complex subunit Duo1 SesA PF17107.5 EEQ40325.1 - 0.44 10.8 2.2 0.59 10.3 0.9 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases APG17 PF04108.12 EEQ40326.1 - 5.3e-73 246.4 9.4 6.2e-73 246.2 9.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 FPP PF05911.11 EEQ40326.1 - 0.077 11.2 3.8 0.11 10.6 2.6 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil Baculo_LEF-11 PF06385.12 EEQ40326.1 - 0.1 13.1 3.5 1.1 9.8 0.1 3.4 3 1 0 3 3 3 0 Baculovirus LEF-11 protein Med30 PF11315.8 EEQ40326.1 - 0.19 11.9 2.7 1.7 8.8 0.0 3.2 2 1 1 4 4 4 0 Mediator complex subunit 30 DUF5344 PF17279.2 EEQ40326.1 - 1.6 9.4 5.3 7.9 7.1 0.1 3.7 3 1 2 5 5 5 0 Family of unknown function (DUF5344) CDC73_C PF05179.14 EEQ40327.1 - 1.4e-49 167.8 0.5 2.3e-49 167.1 0.5 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal tRNA-synt_2b PF00587.25 EEQ40328.1 - 2.5e-40 138.3 0.0 4.3e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEQ40328.1 - 7.9e-18 64.4 0.5 1.4e-17 63.6 0.5 1.4 1 0 0 1 1 1 1 Anticodon binding domain INO80_Ies4 PF08193.11 EEQ40329.1 - 8.2e-08 32.5 12.0 4.6e-07 30.1 3.4 2.1 1 1 1 2 2 2 2 INO80 complex subunit Ies4 DUF202 PF02656.15 EEQ40330.1 - 0.0006 20.2 0.9 0.0013 19.2 0.9 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 EEQ40330.1 - 0.29 11.3 0.0 0.29 11.3 0.0 2.4 3 1 1 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV MDM31_MDM32 PF08118.11 EEQ40331.1 - 1.2e-219 730.4 9.5 1.4e-219 730.1 9.5 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Aminotran_5 PF00266.19 EEQ40332.1 - 1.5e-20 73.5 0.0 1.8e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EEQ40332.1 - 9e-10 38.3 0.0 1.2e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EEQ40332.1 - 0.00012 20.8 0.1 0.00017 20.3 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EEQ40332.1 - 0.0014 18.0 1.3 0.0046 16.3 1.3 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cellulase PF00150.18 EEQ40333.1 - 8.3e-15 55.0 2.2 8.3e-15 55.0 2.2 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.16 EEQ40334.1 - 5.5e-34 117.6 12.4 5.5e-34 117.6 12.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_60s PF00428.19 EEQ40335.1 - 2.4e-26 92.1 15.4 2.9e-26 91.9 15.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L13e PF01294.18 EEQ40336.1 - 2.3e-68 229.6 10.6 2.4e-68 229.5 9.9 1.5 1 1 0 1 1 1 1 Ribosomal protein L13e DUF150_C PF17384.2 EEQ40336.1 - 0.12 12.6 1.8 0.27 11.4 0.2 2.4 2 1 1 3 3 3 0 RimP C-terminal SH3 domain RIC1 PF07064.13 EEQ40337.1 - 9.4e-29 100.6 0.2 1.7e-28 99.7 0.2 1.4 1 0 0 1 1 1 1 RIC1 Complex1_LYR PF05347.15 EEQ40338.1 - 8.9e-12 44.9 1.0 1.6e-11 44.0 1.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ40338.1 - 0.00021 22.0 0.6 0.0003 21.5 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Tubulin_C PF03953.17 EEQ40339.1 - 5.5e-42 142.9 0.0 8.6e-42 142.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 EEQ40339.1 - 2.5e-33 116.0 0.0 4.6e-33 115.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 EEQ40339.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EEQ40339.1 - 0.0039 16.4 0.0 0.0073 15.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin like Ribonuc_L-PSP PF01042.21 EEQ40340.1 - 6.4e-23 81.1 0.0 7.6e-23 80.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP SNARE PF05739.19 EEQ40341.1 - 1.5e-12 47.3 0.0 4.3e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 SNARE domain MCPsignal PF00015.21 EEQ40341.1 - 9.5e-05 22.3 0.6 9.5e-05 22.3 0.6 2.7 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.25 EEQ40341.1 - 0.0001 22.1 9.5 0.00075 19.2 0.5 3.1 2 1 1 3 3 3 2 Syntaxin Syntaxin-5_N PF11416.8 EEQ40341.1 - 0.00032 19.8 0.6 0.00096 18.3 0.6 1.8 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain DUF16 PF01519.16 EEQ40341.1 - 0.0024 18.3 1.3 0.0024 18.3 1.3 2.7 2 1 0 2 2 2 1 Protein of unknown function DUF16 Arch_flagellin PF01917.16 EEQ40341.1 - 0.0094 16.2 0.5 0.035 14.3 0.1 1.9 2 0 0 2 2 2 1 Archaebacterial flagellin FlaC_arch PF05377.11 EEQ40341.1 - 0.03 14.7 0.5 0.03 14.7 0.5 3.4 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) WXG100 PF06013.12 EEQ40341.1 - 0.076 13.3 0.9 2.3 8.5 0.4 2.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Muted PF14942.6 EEQ40341.1 - 0.086 13.2 9.7 0.095 13.0 2.0 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Syntaxin-18_N PF10496.9 EEQ40341.1 - 0.11 12.7 4.0 0.12 12.7 0.6 2.5 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Flagellin_C PF00700.21 EEQ40341.1 - 0.13 12.6 3.8 2.3 8.6 0.2 2.7 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF745 PF05335.13 EEQ40341.1 - 0.17 11.6 8.4 2.4 7.9 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.11 EEQ40341.1 - 0.48 10.7 3.4 1.1 9.6 0.5 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EEQ40341.1 - 0.86 9.6 5.2 0.97 9.5 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Osmo_CC PF08946.10 EEQ40341.1 - 2 8.7 4.5 3.2 8.1 0.2 3.4 4 0 0 4 4 4 0 Osmosensory transporter coiled coil ACCA PF03255.14 EEQ40341.1 - 2.7 7.8 5.6 2 8.3 0.7 2.4 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Snf7 PF03357.21 EEQ40342.1 - 3.1e-44 150.6 21.2 3.1e-44 150.6 21.2 1.8 2 0 0 2 2 2 1 Snf7 Hydantoinase_B PF02538.14 EEQ40342.1 - 0.065 11.6 0.6 0.092 11.1 0.6 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF4407 PF14362.6 EEQ40342.1 - 0.067 12.5 21.9 2 7.7 21.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) NuA4 PF09340.10 EEQ40342.1 - 0.3 11.0 0.2 0.3 11.0 0.2 3.2 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 TetR_C_1 PF02909.17 EEQ40342.1 - 0.67 9.8 3.2 0.74 9.6 1.9 1.9 1 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain YppG PF14179.6 EEQ40342.1 - 2.4 8.9 8.5 7.2 7.4 2.5 3.0 2 1 0 2 2 2 0 YppG-like protein ISG65-75 PF11727.8 EEQ40342.1 - 2.9 7.0 18.1 0.039 13.2 5.1 2.2 1 1 1 2 2 2 0 Invariant surface glycoprotein RNA_pol PF00940.19 EEQ40343.1 - 8.1e-177 588.2 0.0 1.4e-176 587.4 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EEQ40343.1 - 1.8e-100 336.6 0.1 3.5e-100 335.7 0.1 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal UvrA_DNA-bind PF17755.1 EEQ40343.1 - 0.045 14.1 0.4 0.15 12.5 0.4 1.9 1 0 0 1 1 1 0 UvrA DNA-binding domain Mob1_phocein PF03637.17 EEQ40344.1 - 1e-66 224.1 0.7 1.3e-66 223.8 0.7 1.1 1 0 0 1 1 1 1 Mob1/phocein family TFIIF_alpha PF05793.12 EEQ40344.1 - 0.57 8.7 4.0 0.75 8.3 4.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PS_Dcarbxylase PF02666.15 EEQ40345.1 - 5.1e-77 258.0 0.0 5.5e-74 248.0 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase NADH_oxidored PF08040.11 EEQ40345.1 - 0.044 13.5 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 MNLL subunit ANAPC1 PF12859.7 EEQ40346.1 - 9.3e-13 48.9 6.3 6e-12 46.3 6.3 2.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EEQ40346.1 - 0.00036 20.8 5.0 2.5 8.7 0.5 5.4 5 0 0 5 5 5 2 Proteasome/cyclosome repeat PSI_PSAK PF01241.18 EEQ40346.1 - 0.11 12.5 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Photosystem I psaG / psaK GTP_EFTU PF00009.27 EEQ40347.1 - 3.5e-59 199.6 0.2 4.8e-59 199.2 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EEQ40347.1 - 2.7e-25 88.9 0.0 5.7e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EEQ40347.1 - 6e-21 74.6 1.8 2.8e-20 72.5 1.4 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ40347.1 - 3.7e-05 23.8 0.0 8.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ40347.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase cobW PF02492.19 EEQ40347.1 - 0.035 13.7 0.9 0.051 13.2 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EEQ40347.1 - 0.058 13.1 0.5 13 5.5 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PQ-loop PF04193.14 EEQ40348.1 - 1.3e-21 76.1 9.8 1.1e-11 44.4 0.9 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF373 PF04123.13 EEQ40348.1 - 7.6 5.9 10.2 1.5 8.2 6.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Bul1_N PF04425.12 EEQ40349.1 - 1.5e-75 254.7 0.0 7.5e-68 229.3 0.0 2.1 1 1 1 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 EEQ40349.1 - 1.6e-19 70.4 0.1 4.7e-08 32.8 0.0 3.3 1 1 1 2 2 2 2 Bul1 C terminus INCENP_ARK-bind PF03941.15 EEQ40350.1 - 8e-10 38.5 0.2 2.1e-09 37.2 0.2 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region TPR_1 PF00515.28 EEQ40351.1 - 5.4e-11 41.8 15.6 7.7e-06 25.5 1.8 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ40351.1 - 6.2e-11 41.6 10.2 0.0011 18.9 0.9 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ40351.1 - 1.9e-05 25.1 0.2 0.0022 18.5 0.0 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ40351.1 - 4.1e-05 23.8 0.9 0.43 10.9 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ40351.1 - 0.0026 17.7 0.1 5.8 7.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ40351.1 - 0.0043 17.2 13.0 0.5 10.7 0.4 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ40351.1 - 0.042 13.5 3.0 13 5.6 0.0 3.8 3 1 1 4 4 4 0 TPR repeat Pox_T4_N PF04491.12 EEQ40351.1 - 0.042 13.7 0.1 0.36 10.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus T4 protein, N terminus TPR_14 PF13428.6 EEQ40351.1 - 0.071 14.0 0.0 4.6 8.3 0.0 3.5 2 1 1 3 3 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEQ40351.1 - 0.11 12.6 8.2 2.5 8.3 0.1 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Ploopntkinase2 PF18747.1 EEQ40351.1 - 0.13 11.5 1.2 0.2 10.9 1.2 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase2 TPR_9 PF13371.6 EEQ40351.1 - 0.13 12.4 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Bul1_N PF04425.12 EEQ40352.1 - 4.1e-93 312.6 0.7 7.6e-92 308.4 0.7 2.1 1 1 0 1 1 1 1 Bul1 N terminus Bul1_C PF04426.12 EEQ40352.1 - 9.3e-23 81.0 1.7 9.3e-23 81.0 1.7 2.1 2 1 0 2 2 2 1 Bul1 C terminus G_glu_transpept PF01019.21 EEQ40353.1 - 1.9e-136 455.8 0.1 2.3e-136 455.6 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Carn_acyltransf PF00755.20 EEQ40354.1 - 1.4e-210 700.9 0.0 1.8e-210 700.5 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1708 PF08101.11 EEQ40355.1 - 9.7e-128 427.0 0.2 7.9e-108 361.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) bZIP_1 PF00170.21 EEQ40356.1 - 1.3e-06 28.4 2.3 1.3e-06 28.4 2.3 2.5 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ40356.1 - 0.0039 17.2 3.2 0.0039 17.2 3.2 3.2 3 0 0 3 3 3 1 Basic region leucine zipper Aft1_OSA PF11785.8 EEQ40356.1 - 0.038 14.4 3.2 0.054 13.9 0.2 2.8 2 0 0 2 2 2 0 Aft1 osmotic stress response (OSM) domain Aft1_HRA PF11786.8 EEQ40356.1 - 2 8.8 20.7 0.019 15.3 9.9 3.4 2 2 0 2 2 2 0 Aft1 HRA domain Glyco_hydro_47 PF01532.20 EEQ40357.1 - 2.6e-170 567.2 0.1 3.2e-170 567.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 EEQ40357.1 - 0.0028 16.8 0.4 0.34 9.9 0.1 2.4 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 EEQ40357.1 - 0.058 12.9 0.8 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 EEQ40357.1 - 0.088 12.0 0.1 1.3 8.2 0.0 2.5 3 0 0 3 3 3 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) UPF0240 PF06784.11 EEQ40357.1 - 0.64 10.1 6.2 2.2 8.3 6.5 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) Zn_clus PF00172.18 EEQ40358.1 - 0.00017 21.6 9.6 0.00031 20.8 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gon7 PF08738.10 EEQ40358.1 - 0.089 12.9 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Gon7 family Spc24 PF08286.11 EEQ40358.1 - 3.1 8.1 6.3 2.6 8.3 0.4 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Cyt-b5 PF00173.28 EEQ40360.1 - 1.6e-11 44.2 0.0 2.5e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF684 PF05075.14 EEQ40360.1 - 0.1 11.6 0.1 0.22 10.5 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF684) Cys_Met_Meta_PP PF01053.20 EEQ40361.1 - 6.2e-34 117.2 0.0 8.4e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EEQ40361.1 - 0.00036 19.8 0.0 0.00099 18.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II DUF2716 PF10898.8 EEQ40361.1 - 0.075 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2716) PDE6_gamma PF04868.12 EEQ40361.1 - 0.16 12.2 0.1 0.61 10.4 0.0 2.1 2 0 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit HMG-CoA_red PF00368.18 EEQ40362.1 - 8.9e-145 482.3 0.9 1.3e-144 481.8 0.9 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 EEQ40362.1 - 2e-13 50.4 8.0 5.5e-13 49.0 8.0 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation HPIH PF13323.6 EEQ40362.1 - 9.6e-11 41.8 1.7 1.3e-09 38.1 1.7 2.5 1 1 0 1 1 1 1 N-terminal domain with HPIH motif Patched PF02460.18 EEQ40362.1 - 1.1e-06 27.0 6.4 1.7e-06 26.4 6.4 1.2 1 0 0 1 1 1 1 Patched family DUF485 PF04341.12 EEQ40362.1 - 2.8 8.0 7.1 1 9.4 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Tubulin PF00091.25 EEQ40364.1 - 1.8e-58 198.0 0.0 2.6e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EEQ40364.1 - 2.2e-09 37.6 0.0 4.3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EEQ40364.1 - 0.00079 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EEQ40364.1 - 0.071 12.3 0.0 0.23 10.6 0.0 1.7 2 0 0 2 2 2 0 Tubulin like Aminotran_1_2 PF00155.21 EEQ40365.1 - 2e-24 86.5 0.0 2.9e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II BAR_2 PF10455.9 EEQ40366.1 - 3.1e-60 203.7 9.7 5.8e-60 202.9 9.7 1.4 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EEQ40366.1 - 5.6e-16 58.9 6.4 2.5e-15 56.8 6.4 1.9 1 1 0 1 1 1 1 BAR domain Arfaptin PF06456.13 EEQ40366.1 - 2.1e-05 24.2 2.7 0.022 14.4 0.6 2.2 2 0 0 2 2 2 2 Arfaptin-like domain ACDC PF14733.6 EEQ40366.1 - 0.0094 16.2 1.4 0.15 12.4 0.2 2.7 3 0 0 3 3 3 1 AP2-coincident C-terminal HTH_44 PF14641.6 EEQ40366.1 - 0.016 15.7 0.1 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix DNA-binding domain of SPT6 Csm2_III-A PF03750.13 EEQ40366.1 - 0.052 14.4 1.4 0.052 14.4 1.4 2.5 2 2 0 2 2 2 0 Csm2 Type III-A ApoLp-III PF07464.11 EEQ40366.1 - 0.88 9.6 14.5 2.2 8.4 0.9 4.2 2 2 1 4 4 4 0 Apolipophorin-III precursor (apoLp-III) zf-RING_9 PF13901.6 EEQ40366.1 - 2.4 8.1 4.6 1.8 8.5 2.0 2.0 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon Fib_alpha PF08702.10 EEQ40366.1 - 3.2 8.0 9.0 1.6 8.9 0.3 2.6 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family AA_kinase PF00696.28 EEQ40367.1 - 5.1e-46 157.2 0.0 1.1e-45 156.1 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 EEQ40367.1 - 7.4e-07 28.8 0.8 0.0013 18.4 0.3 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 EEQ40367.1 - 1.5e-06 27.9 2.8 4.4e-05 23.2 0.7 2.6 2 0 0 2 2 2 2 ACT domain Ofd1_CTDD PF10637.9 EEQ40368.1 - 2.5e-91 305.5 0.2 2.2e-89 299.2 0.1 2.5 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EEQ40368.1 - 2.2e-27 95.6 0.0 5.6e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EEQ40368.1 - 1.5e-13 51.5 0.0 4.1e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EEQ40368.1 - 0.12 12.9 0.0 0.54 10.8 0.0 2.1 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NAD_binding_1 PF00175.21 EEQ40369.1 - 4e-32 111.1 0.0 1.3e-31 109.5 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EEQ40369.1 - 3.8e-30 104.2 0.0 6.6e-30 103.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EEQ40369.1 - 2e-06 28.0 0.0 0.00078 19.6 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Vps62 PF06101.11 EEQ40370.1 - 1.4e-10 40.2 3.6 1.4e-10 40.2 3.6 1.4 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 AA_permease PF00324.21 EEQ40371.1 - 2.5e-138 461.7 43.9 2.9e-138 461.5 43.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ40371.1 - 1.2e-39 136.4 46.6 1.4e-39 136.2 46.6 1.0 1 0 0 1 1 1 1 Amino acid permease RTP PF02334.16 EEQ40371.1 - 0.17 12.5 0.0 0.3 11.7 0.0 1.3 1 0 0 1 1 1 0 Replication terminator protein DUF3384 PF11864.8 EEQ40372.1 - 8.8e-98 328.3 15.0 2.2e-97 326.9 15.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EEQ40372.1 - 3.9e-46 156.9 0.1 8.4e-46 155.9 0.1 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EEQ40372.1 - 1.6e-24 86.7 0.5 5.3e-24 85.0 0.5 1.8 1 1 0 1 1 1 1 Tuberin SIS PF01380.22 EEQ40373.1 - 3.4e-11 43.1 0.5 9.7e-11 41.6 0.1 2.0 2 1 0 2 2 2 1 SIS domain SIS_2 PF13580.6 EEQ40373.1 - 7.8e-05 22.7 0.0 0.00041 20.4 0.0 2.1 1 1 1 2 2 2 1 SIS domain PUF PF00806.19 EEQ40374.1 - 1.7e-64 210.0 16.1 2.5e-08 33.1 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat THP2 PF09432.10 EEQ40374.1 - 0.024 14.7 0.5 0.067 13.2 0.5 1.7 1 0 0 1 1 1 0 Tho complex subunit THP2 sCache_2 PF17200.4 EEQ40374.1 - 0.15 11.9 0.3 88 2.9 0.0 4.0 4 1 1 5 5 5 0 Single Cache domain 2 BRAP2 PF07576.12 EEQ40375.1 - 0.016 15.4 0.1 0.043 14.0 0.0 1.7 2 0 0 2 2 2 0 BRCA1-associated protein 2 WD40 PF00400.32 EEQ40376.1 - 6.2e-05 23.7 2.5 1 10.3 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ40376.1 - 0.00058 20.1 0.1 0.38 11.1 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 EEQ40377.1 - 2.2e-31 105.4 24.6 0.00051 20.0 0.1 12.0 13 0 0 13 13 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ40377.1 - 6.6e-30 101.7 18.5 6.4e-05 22.6 0.0 11.1 11 0 0 11 11 11 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ40377.1 - 8.4e-28 96.4 21.7 3.6e-23 81.6 0.9 5.9 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EEQ40377.1 - 2.1e-19 69.5 25.4 1.5e-08 34.8 0.4 9.2 5 1 5 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ40377.1 - 3.4e-19 67.4 20.9 0.0013 18.7 0.1 9.7 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ40377.1 - 1.1e-15 56.9 5.3 0.0034 18.1 0.0 9.9 8 2 4 12 12 10 2 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ40377.1 - 4.4e-13 49.7 9.6 0.13 12.9 0.0 8.3 7 1 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ40377.1 - 3.3e-11 43.5 14.5 0.028 14.9 0.1 8.0 4 3 6 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ40377.1 - 5.3e-10 38.6 7.7 0.02 14.9 0.0 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ40377.1 - 7.3e-09 35.7 7.3 2.6 8.9 0.1 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ40377.1 - 1.2e-08 35.0 0.4 0.0003 20.9 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EEQ40377.1 - 1.5e-08 34.2 0.1 0.072 12.3 0.0 3.9 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ40377.1 - 3.6e-08 33.2 16.0 1.2 9.6 0.0 9.2 8 1 1 9 9 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ40377.1 - 8.3e-08 31.8 8.2 0.035 13.8 0.0 7.2 5 2 3 8 8 7 2 TPR repeat TPR_MalT PF17874.1 EEQ40377.1 - 4.2e-07 29.7 1.2 2.7e-05 23.7 0.0 3.5 3 1 1 4 4 4 1 MalT-like TPR region TPR_10 PF13374.6 EEQ40377.1 - 7.6e-07 28.8 10.3 0.49 10.3 0.3 8.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_21 PF09976.9 EEQ40377.1 - 0.0014 18.3 1.2 1.9 8.2 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 EEQ40377.1 - 0.0037 16.7 6.3 0.44 9.9 0.4 4.0 3 2 1 4 4 4 2 Coatomer epsilon subunit SRP_TPR_like PF17004.5 EEQ40377.1 - 0.011 15.8 5.3 0.5 10.4 0.0 3.6 3 1 0 3 3 3 0 Putative TPR-like repeat ANAPC8 PF04049.13 EEQ40377.1 - 0.053 13.6 2.3 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 TPR_3 PF07720.12 EEQ40377.1 - 0.28 11.2 8.2 3 8.0 0.1 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EEQ40377.1 - 0.4 10.8 5.0 16 5.6 0.0 4.8 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat WD40 PF00400.32 EEQ40378.1 - 3.6e-24 84.6 6.6 2.4e-06 28.2 0.2 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ40378.1 - 6.5e-07 29.6 2.1 0.014 15.7 0.1 4.4 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EEQ40378.1 - 2.4e-05 23.3 1.7 0.77 8.4 0.0 3.4 2 1 1 3 3 3 3 Nup133 N terminal like Nup160 PF11715.8 EEQ40378.1 - 0.00087 18.0 0.1 0.2 10.3 0.0 2.5 3 0 0 3 3 3 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EEQ40378.1 - 0.0012 17.9 0.1 0.0038 16.2 0.0 1.9 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain BBS2_Mid PF14783.6 EEQ40378.1 - 0.0088 16.1 0.2 3.6 7.7 0.0 4.0 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region CPSF_A PF03178.15 EEQ40378.1 - 0.051 12.9 0.1 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 CPSF A subunit region AlaDh_PNT_N PF05222.15 EEQ40379.1 - 1.5e-29 103.0 0.0 3.4e-29 101.9 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EEQ40379.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BACK PF07707.15 EEQ40380.1 - 0.041 14.0 1.6 0.066 13.3 0.3 2.0 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF763 PF05559.11 EEQ40380.1 - 0.075 12.2 0.2 0.16 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Trans_reg_C PF00486.28 EEQ40380.1 - 0.1 12.7 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal DUF1912 PF08930.10 EEQ40380.1 - 0.37 11.0 2.2 1 9.6 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1912) FGGY_N PF00370.21 EEQ40381.1 - 4.7e-17 62.4 0.0 9.8e-10 38.4 0.0 2.9 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EEQ40381.1 - 9.9e-12 45.0 0.0 5.4e-11 42.6 0.0 2.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain PhageMin_Tail PF10145.9 EEQ40381.1 - 0.13 12.1 0.0 0.36 10.7 0.0 1.7 2 0 0 2 2 2 0 Phage-related minor tail protein Hap4_Hap_bind PF10297.9 EEQ40382.1 - 8.3e-08 32.1 3.8 2e-07 30.9 3.8 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DASH_Dad1 PF08649.10 EEQ40382.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 DUF4515 PF14988.6 EEQ40382.1 - 0.2 11.4 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) Aldedh PF00171.22 EEQ40383.1 - 8.7e-137 456.4 0.4 9.9e-137 456.2 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PsaX PF08078.12 EEQ40384.1 - 0.019 14.9 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 PsaX family NB PF04159.13 EEQ40384.1 - 7.7 6.6 7.6 23 5.1 0.9 2.3 1 1 1 2 2 2 0 NB glycoprotein GDE_C PF06202.14 EEQ40385.1 - 3.1e-41 141.6 0.0 3.4e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase GDE_C PF06202.14 EEQ40386.1 - 8.6e-05 21.6 0.0 8.9e-05 21.6 0.0 1.0 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hDGE_amylase PF14701.6 EEQ40388.1 - 2.6e-174 580.5 0.0 3.9e-174 579.9 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain hGDE_central PF14702.6 EEQ40388.1 - 6.9e-79 265.1 0.0 1.3e-78 264.2 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme GDE_C PF06202.14 EEQ40388.1 - 4.4e-43 147.7 0.0 7.6e-43 146.9 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_N PF14699.6 EEQ40388.1 - 1.9e-23 82.4 0.4 3.6e-23 81.5 0.4 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 EEQ40388.1 - 9.3e-08 32.0 0.0 3.6e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, catalytic domain THOC2_N PF16134.5 EEQ40389.1 - 5.9e-174 580.2 3.5 5.9e-174 580.2 3.5 2.5 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EEQ40389.1 - 8.1e-76 255.1 5.8 8.1e-76 255.1 5.8 2.6 2 0 0 2 2 2 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EEQ40389.1 - 1.2e-25 89.4 0.1 3.5e-25 87.9 0.1 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit zf-C2H2 PF00096.26 EEQ40390.1 - 2.3e-26 90.7 78.0 0.00013 22.2 1.9 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ40390.1 - 1.5e-15 56.5 72.0 0.097 13.6 0.3 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EEQ40390.1 - 1.1e-05 25.6 0.3 1.1e-05 25.6 0.3 10.2 9 1 1 10 10 10 3 Zinc-finger double domain zf-met PF12874.7 EEQ40390.1 - 3.3e-05 24.1 34.8 1.7 9.2 0.9 8.0 7 0 0 7 7 7 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EEQ40390.1 - 0.0013 19.0 33.9 2.3 8.6 0.2 8.3 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding DrrA_P4M PF14860.6 EEQ40390.1 - 0.032 14.1 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain Insulin_TMD PF17870.1 EEQ40391.1 - 0.072 13.2 0.2 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Plasmodium_Vir PF05795.11 EEQ40391.1 - 0.38 10.1 3.1 0.12 11.8 0.2 1.5 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Abhydrolase_1 PF00561.20 EEQ40392.1 - 1.7e-10 41.0 0.1 2.9e-09 36.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ40392.1 - 8.2e-10 39.7 0.0 1.7e-09 38.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ40392.1 - 2.7e-08 33.4 0.0 3.6e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EEQ40392.1 - 2.2e-05 24.7 0.1 4.2e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF2920 PF11144.8 EEQ40392.1 - 0.0018 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Esterase PF00756.20 EEQ40392.1 - 0.008 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EEQ40392.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein CBFD_NFYB_HMF PF00808.23 EEQ40393.1 - 1.8e-14 53.8 2.6 1.8e-14 53.8 2.6 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ40393.1 - 0.0018 18.7 0.7 0.0029 18.0 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Orthopox_B11R PF07033.11 EEQ40393.1 - 0.052 13.3 1.3 0.052 13.3 1.3 2.3 2 2 0 2 2 2 0 Orthopoxvirus B11R protein Yos1 PF08571.10 EEQ40394.1 - 1.7e-32 111.5 1.8 2e-32 111.3 1.8 1.0 1 0 0 1 1 1 1 Yos1-like Dexa_ind PF15198.6 EEQ40394.1 - 0.044 13.9 0.2 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 Dexamethasone-induced TMEM191C PF15194.6 EEQ40394.1 - 0.08 13.1 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 TMEM191C family IBN_N PF03810.19 EEQ40395.1 - 1.8e-11 43.8 0.0 5.6e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 EEQ40395.1 - 3e-11 42.8 8.7 5.6e-10 38.6 0.1 4.0 2 2 2 4 4 4 2 Cse1 S-AdoMet_synt_M PF02772.16 EEQ40395.1 - 0.033 14.4 1.3 0.098 12.9 0.1 2.4 3 0 0 3 3 3 0 S-adenosylmethionine synthetase, central domain DUF2115 PF09888.9 EEQ40395.1 - 0.064 13.8 0.2 19 5.7 0.1 3.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Urb2 PF10441.9 EEQ40395.1 - 0.1 12.5 0.7 0.37 10.7 0.3 2.3 2 1 0 2 2 2 0 Urb2/Npa2 family Telomere_reg-2 PF10193.9 EEQ40395.1 - 0.55 10.7 5.4 1.1 9.7 0.2 3.3 2 1 2 4 4 4 0 Telomere length regulation protein DUF3385 PF11865.8 EEQ40395.1 - 1.4 8.8 5.4 4.9 7.0 0.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) UFD1 PF03152.14 EEQ40396.1 - 4.1e-72 241.3 0.0 5.4e-72 240.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NPR3 PF03666.13 EEQ40396.1 - 0.093 11.5 0.5 0.14 10.9 0.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HSP70 PF00012.20 EEQ40397.1 - 1.5e-43 148.9 0.1 2.1e-43 148.5 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.16 EEQ40397.1 - 0.00014 21.6 0.0 0.0018 18.0 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DsrC PF04358.13 EEQ40398.1 - 0.02 15.4 6.6 0.4 11.2 1.7 2.6 1 1 1 2 2 2 0 DsrC like protein DUF2235 PF09994.9 EEQ40398.1 - 0.048 13.0 0.9 0.09 12.1 0.9 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Muted PF14942.6 EEQ40398.1 - 0.53 10.6 25.1 0.75 10.1 11.7 2.5 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein RRM_1 PF00076.22 EEQ40399.1 - 2.6e-11 43.2 0.6 0.00045 20.0 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ40399.1 - 0.047 13.5 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif SWM_repeat PF13753.6 EEQ40399.1 - 0.059 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative flagellar system-associated repeat RabGAP-TBC PF00566.18 EEQ40400.1 - 3.2e-35 121.7 0.3 4.8e-35 121.2 0.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MIF4G PF02854.19 EEQ40400.1 - 0.24 11.0 0.0 0.24 11.0 0.0 1.8 3 0 0 3 3 3 0 MIF4G domain RRM_Rrp7 PF17799.1 EEQ40401.1 - 4.8e-59 198.8 0.2 9.4e-59 197.8 0.2 1.5 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 EEQ40401.1 - 1.3e-29 102.7 16.5 2.3e-29 101.9 16.5 1.4 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 EEQ40401.1 - 0.0076 16.5 0.1 0.0076 16.5 0.1 2.8 3 1 0 3 3 3 1 Domain of unknown function (DUF5093) Ribosomal_L14e PF01929.17 EEQ40401.1 - 0.17 12.4 8.1 0.19 12.3 4.2 2.9 3 1 0 3 3 3 0 Ribosomal protein L14 DUF45 PF01863.17 EEQ40401.1 - 0.35 10.9 7.1 0.37 10.8 5.8 1.6 2 0 0 2 2 2 0 Protein of unknown function DUF45 DUF3837 PF12939.7 EEQ40401.1 - 6.1 7.3 8.4 8.1 6.9 3.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) Aminotran_4 PF01063.19 EEQ40402.1 - 2.9e-25 89.4 0.0 4e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV PUFD PF16553.5 EEQ40402.1 - 0.048 13.8 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 BCORL-PCGF1-binding domain USP7_C2 PF14533.6 EEQ40402.1 - 0.058 13.1 0.0 0.095 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal HAD PF12710.7 EEQ40403.1 - 3.4e-16 60.2 0.1 4.9e-16 59.7 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EEQ40403.1 - 1.2e-15 58.3 1.3 1.9e-15 57.7 1.3 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ40403.1 - 5.8e-13 49.2 0.4 1.9e-10 40.9 0.1 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ40403.1 - 0.0011 19.1 1.5 0.039 14.0 1.5 2.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Glyco_hydro_31 PF01055.26 EEQ40403.1 - 0.039 13.1 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 S6PP PF05116.13 EEQ40403.1 - 0.043 13.3 0.7 3.6 7.0 0.0 2.8 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase LPD22 PF18834.1 EEQ40403.1 - 0.091 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 22 CRAL_TRIO PF00650.20 EEQ40404.1 - 5.3e-36 123.7 0.0 8.8e-36 123.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EEQ40404.1 - 2.5e-18 66.0 0.5 4.6e-18 65.2 0.5 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain NNMT_PNMT_TEMT PF01234.17 EEQ40404.1 - 0.15 11.3 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Tctex-1 PF03645.13 EEQ40405.1 - 9.4e-10 38.7 1.0 1.4e-09 38.1 0.9 1.3 1 1 0 1 1 1 1 Tctex-1 family Y_Y_Y PF07495.13 EEQ40405.1 - 0.069 13.1 2.2 1.9 8.5 0.2 2.4 2 1 0 2 2 2 0 Y_Y_Y domain BRX_N PF13713.6 EEQ40405.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain CENP-Q PF13094.6 EEQ40406.1 - 1.3e-23 84.0 5.1 1.3e-23 84.0 5.1 1.6 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit SOAR PF16533.5 EEQ40406.1 - 0.011 15.6 0.2 0.033 14.2 0.2 1.8 1 0 0 1 1 1 0 STIM1 Orai1-activating region MutS_III PF05192.18 EEQ40406.1 - 0.2 11.8 3.5 0.27 11.4 3.5 1.5 1 1 0 1 1 1 0 MutS domain III zf-RRN7 PF11781.8 EEQ40407.1 - 2.2e-07 30.4 2.2 2.6e-07 30.2 0.9 1.9 1 1 1 2 2 2 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Aldedh PF00171.22 EEQ40409.1 - 2.7e-179 596.5 3.1 3.1e-179 596.3 3.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EEQ40409.1 - 0.0018 17.8 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 EEQ40409.1 - 0.026 13.6 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) IPK PF03770.16 EEQ40411.1 - 7.9e-50 169.5 0.0 1.3e-49 168.7 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Glyco_transf_15 PF01793.16 EEQ40412.1 - 4.9e-109 364.5 8.2 6e-109 364.2 8.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF512 PF04459.12 EEQ40412.1 - 0.17 11.1 0.2 0.38 10.0 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF512) Mannosyl_trans3 PF11051.8 EEQ40413.1 - 3.5e-78 262.8 0.0 1.2e-77 261.0 0.0 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative DUF5643 PF18705.1 EEQ40413.1 - 0.17 11.8 0.2 17 5.4 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5643) Clat_adaptor_s PF01217.20 EEQ40414.1 - 2.1e-50 170.3 1.6 3e-50 169.8 1.6 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DEAD PF00270.29 EEQ40415.1 - 3.8e-49 166.8 0.0 8.6e-49 165.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ40415.1 - 6.3e-23 81.2 0.1 1.7e-21 76.6 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EEQ40415.1 - 2.9e-16 59.5 8.6 2.9e-16 59.5 8.6 2.6 2 0 0 2 2 2 1 DBP10CT (NUC160) domain RRM_1 PF00076.22 EEQ40416.1 - 5.9e-33 112.5 0.1 1.7e-15 56.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ40416.1 - 2.3e-11 43.7 0.1 2.7e-06 27.4 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif SUIM_assoc PF16619.5 EEQ40416.1 - 0.0034 17.4 0.2 0.0034 17.4 0.2 6.7 3 2 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Nup35_RRM_2 PF14605.6 EEQ40416.1 - 0.07 13.1 0.1 11 6.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif UPF0020 PF01170.18 EEQ40417.1 - 3.6e-09 36.6 0.0 2.6e-07 30.5 0.0 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 EEQ40417.1 - 0.16 11.6 0.0 0.37 10.4 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Thi4 PF01946.17 EEQ40419.1 - 1.8e-74 249.9 0.0 2.2e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Thi4 family CPSF73-100_C PF11718.8 EEQ40420.1 - 1.8e-65 220.6 5.5 3e-65 219.8 5.5 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EEQ40420.1 - 2.1e-32 111.7 0.1 6.2e-32 110.2 0.1 1.9 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EEQ40420.1 - 1.2e-19 71.1 0.1 3.2e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EEQ40420.1 - 4.6e-18 65.4 0.0 1.2e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EEQ40420.1 - 9.9e-15 54.2 0.0 2.2e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_3 PF13483.6 EEQ40420.1 - 9.1e-06 25.7 0.0 3.6e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 EEQ40420.1 - 3.1e-05 23.6 0.3 0.00062 19.3 0.2 2.7 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EEQ40420.1 - 0.0024 17.1 0.1 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 Putative beta-lactamase-like family CPSF100_C PF13299.6 EEQ40420.1 - 0.44 10.7 4.5 0.18 12.0 1.7 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal LSM PF01423.22 EEQ40421.1 - 1.4e-18 66.3 0.2 1.9e-18 65.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EEQ40421.1 - 0.0063 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Hfq protein SPECT1 PF18680.1 EEQ40421.1 - 0.067 12.9 0.2 0.1 12.2 0.2 1.3 1 1 0 1 1 1 0 Plasmodium host cell traversal SPECT1 Hus1 PF04005.12 EEQ40422.1 - 1.5e-67 227.8 0.3 1.7e-67 227.6 0.3 1.0 1 0 0 1 1 1 1 Hus1-like protein DAP_epimerase PF01678.19 EEQ40422.1 - 0.012 15.8 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelate epimerase Aminotran_5 PF00266.19 EEQ40423.1 - 1.3e-38 132.9 0.0 1.6e-38 132.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V GTP_EFTU PF00009.27 EEQ40424.1 - 1.2e-49 168.5 0.0 2.3e-49 167.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EEQ40424.1 - 3.7e-39 133.2 10.4 5.1e-39 132.7 6.6 2.4 2 0 0 2 2 2 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EEQ40424.1 - 1.2e-22 79.7 0.0 2.6e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ40424.1 - 6.9e-10 39.2 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ40424.1 - 4.5e-05 23.5 0.2 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EEQ40424.1 - 0.00025 20.7 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EEQ40424.1 - 0.0046 16.4 0.2 0.032 13.6 0.0 2.3 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 EEQ40424.1 - 0.006 16.7 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1_Xtn PF16897.5 EEQ40424.1 - 0.0069 16.4 0.1 0.087 12.9 0.0 2.7 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain RF3_C PF16658.5 EEQ40424.1 - 0.0084 15.9 0.1 0.026 14.3 0.0 1.8 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain PALP PF00291.25 EEQ40425.1 - 5.2e-77 259.1 0.0 7.9e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EEQ40425.1 - 7.5e-48 160.2 1.7 6e-28 96.5 0.1 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DAPDH_C PF16654.5 EEQ40425.1 - 0.023 14.5 0.2 0.048 13.5 0.2 1.5 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain EF-hand_1 PF00036.32 EEQ40426.1 - 1.7e-16 58.4 0.2 0.00011 21.5 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EEQ40426.1 - 4e-13 48.2 3.4 0.00015 21.4 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EEQ40426.1 - 2.2e-12 45.9 0.9 2.3e-05 23.7 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EEQ40426.1 - 1.2e-11 44.9 6.0 1.8e-06 28.3 0.2 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EEQ40426.1 - 1.9e-09 37.2 4.3 1.7e-05 24.6 0.0 4.2 3 2 1 4 4 4 3 EF-hand domain pair S10_plectin PF03501.15 EEQ40427.1 - 4.2e-34 116.5 0.0 5.1e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Histone PF00125.24 EEQ40427.1 - 0.04 14.3 0.0 0.058 13.7 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF4364 PF14277.6 EEQ40427.1 - 0.056 13.2 0.1 0.074 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) PadR PF03551.14 EEQ40427.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family YlbD_coat PF14071.6 EEQ40428.1 - 0.27 11.5 4.3 1.1 9.5 4.3 2.1 1 0 0 1 1 1 0 Putative coat protein Imm44 PF15571.6 EEQ40428.1 - 0.34 11.1 4.6 0.29 11.4 0.5 2.4 2 0 0 2 2 2 0 Immunity protein 44 Septin PF00735.18 EEQ40430.1 - 8.6e-83 277.8 0.0 1.2e-82 277.3 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EEQ40430.1 - 7.5e-05 22.8 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 EEQ40430.1 - 0.0011 18.1 0.0 0.0025 17.0 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.12 EEQ40430.1 - 0.0079 15.7 0.4 0.019 14.5 0.1 1.7 2 0 0 2 2 2 1 Poxvirus A32 protein RsgA_GTPase PF03193.16 EEQ40430.1 - 0.011 15.7 0.3 0.052 13.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EEQ40430.1 - 0.018 15.3 0.0 0.066 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EEQ40430.1 - 0.02 14.0 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 EEQ40430.1 - 0.045 14.3 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ40430.1 - 0.049 14.2 0.0 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 EEQ40430.1 - 0.076 13.2 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EEQ40430.1 - 0.091 12.5 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EEQ40430.1 - 0.12 12.7 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PIN_5 PF08745.11 EEQ40431.1 - 0.0018 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 PINc domain ribonuclease PIN_4 PF13638.6 EEQ40431.1 - 0.003 17.8 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 PIN domain SNF2_N PF00176.23 EEQ40432.1 - 9.5e-71 238.3 1.9 9.5e-71 238.3 1.9 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ40432.1 - 8.3e-21 74.4 1.4 1.7e-18 66.9 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EEQ40432.1 - 9.7e-20 70.4 0.3 3.1e-19 68.8 0.3 2.0 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 EEQ40432.1 - 1.2e-13 51.4 3.0 1.2e-13 51.4 3.0 3.8 4 0 0 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex ResIII PF04851.15 EEQ40432.1 - 1.2e-08 35.2 0.3 1.2e-08 35.2 0.3 3.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 EEQ40432.1 - 7.5e-06 26.2 11.5 7.5e-06 26.2 11.5 3.3 3 0 0 3 3 3 1 HSA QLQ PF08880.11 EEQ40432.1 - 8e-05 22.3 1.9 8e-05 22.3 1.9 3.2 2 0 0 2 2 2 1 QLQ Vps36_ESCRT-II PF11605.8 EEQ40433.1 - 0.015 15.5 0.0 0.024 14.8 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 DUF1684 PF07920.11 EEQ40433.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) RrnaAD PF00398.20 EEQ40434.1 - 6.6e-29 100.8 0.1 9.1e-29 100.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Suf PF05843.14 EEQ40435.1 - 1e-53 183.3 26.1 2.3e-46 159.1 7.0 5.0 3 3 4 7 7 7 3 Suppressor of forked protein (Suf) Tom37 PF10568.9 EEQ40436.1 - 6.5e-32 110.5 2.8 7.2e-32 110.3 1.8 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 EEQ40436.1 - 5.4e-06 27.1 0.1 2.1e-05 25.2 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase N-terminal domain DUF2129 PF09902.9 EEQ40436.1 - 0.04 14.0 0.8 0.081 13.0 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) DUF4448 PF14610.6 EEQ40437.1 - 1.7e-59 200.8 0.0 1.7e-59 200.8 0.0 1.6 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) SID-1_RNA_chan PF13965.6 EEQ40437.1 - 0.17 10.3 0.1 0.38 9.1 0.0 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Zip PF02535.22 EEQ40438.1 - 3.8e-24 85.5 16.6 6e-22 78.3 16.5 2.4 1 1 0 1 1 1 1 ZIP Zinc transporter PNRC PF15365.6 EEQ40439.1 - 1.3e-07 31.2 4.0 1.3e-07 31.2 4.0 3.3 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif EPL1 PF10513.9 EEQ40439.1 - 0.0018 18.7 6.9 0.0043 17.4 6.9 1.7 1 1 0 1 1 1 1 Enhancer of polycomb-like Cation_efflux PF01545.21 EEQ40440.1 - 6.7e-17 61.9 0.1 9e-17 61.5 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.21 EEQ40442.1 - 4.3e-36 124.5 2.8 4.9e-36 124.3 2.8 1.0 1 0 0 1 1 1 1 Cation efflux family DUF4199 PF13858.6 EEQ40442.1 - 0.034 14.6 1.6 0.037 14.4 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Opi1 PF08618.10 EEQ40443.1 - 8.4e-20 71.4 13.8 1.4e-07 31.2 0.0 4.2 3 1 1 4 4 4 3 Transcription factor Opi1 MHC2-interact PF09307.10 EEQ40444.1 - 0.0076 16.2 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 CLIP, MHC2 interacting Protocadherin PF08374.11 EEQ40444.1 - 0.038 14.0 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Protocadherin ETC_C1_NDUFA5 PF04716.14 EEQ40445.1 - 8.2e-26 89.6 0.1 1.3e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Ras PF00071.22 EEQ40446.1 - 3.3e-64 215.4 0.3 3.8e-64 215.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ40446.1 - 1.2e-36 125.6 0.2 1.8e-36 125.0 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ40446.1 - 1.2e-16 60.6 0.1 1.5e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EEQ40446.1 - 6.7e-08 32.2 0.1 8.4e-08 31.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EEQ40446.1 - 1.1e-06 28.4 0.1 3.4e-06 26.7 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EEQ40446.1 - 2.2e-05 23.9 0.0 3.9e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEQ40446.1 - 3.8e-05 23.8 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ40446.1 - 3.9e-05 23.6 0.6 0.16 11.9 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EEQ40446.1 - 9.7e-05 21.9 0.1 0.00041 19.9 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 EEQ40446.1 - 0.0032 16.8 0.7 0.011 15.0 0.1 2.0 2 0 0 2 2 2 1 Septin AAA_7 PF12775.7 EEQ40446.1 - 0.0079 15.7 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EEQ40446.1 - 0.01 16.1 0.4 0.15 12.3 0.1 2.4 1 1 1 2 2 2 0 AAA domain CENP-M PF11111.8 EEQ40446.1 - 0.013 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) AAA_16 PF13191.6 EEQ40446.1 - 0.028 14.8 0.1 0.052 13.9 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EEQ40446.1 - 0.031 14.0 0.8 0.13 12.0 0.8 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EEQ40446.1 - 0.049 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EEQ40446.1 - 0.081 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein MCM PF00493.23 EEQ40446.1 - 0.095 11.8 0.0 0.25 10.4 0.0 1.6 2 1 0 2 2 2 0 MCM P-loop domain ABC_tran PF00005.27 EEQ40446.1 - 0.13 12.8 1.5 0.46 11.0 1.4 1.9 1 1 0 1 1 1 0 ABC transporter tRNA_synthFbeta PF17759.1 EEQ40449.1 - 1.1e-40 139.4 0.0 1.3e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B5 PF03484.15 EEQ40449.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase B5 domain PhetRS_B1 PF18262.1 EEQ40450.1 - 1.7e-29 101.8 0.5 9.4e-29 99.5 0.2 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EEQ40450.1 - 7.5e-28 97.4 0.0 1.4e-27 96.5 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EEQ40450.1 - 2.4e-10 40.6 0.1 7.4e-07 29.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF726 PF05277.12 EEQ40451.1 - 1.9e-126 421.7 1.7 3e-126 421.0 1.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF726) ETRAMP PF09716.10 EEQ40451.1 - 0.29 11.2 3.5 0.15 12.1 0.3 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF2951 PF11166.8 EEQ40451.1 - 4.3 7.6 6.7 1.7 8.9 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Methyltransf_34 PF11312.8 EEQ40453.1 - 1.6e-90 303.5 0.2 2.3e-90 303.0 0.2 1.2 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase DUF1619 PF07773.11 EEQ40453.1 - 0.0026 17.7 0.0 0.0041 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1619) SIR2 PF02146.17 EEQ40454.1 - 7.3e-56 188.9 0.0 1e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family NFACT-C PF11923.8 EEQ40456.1 - 1.9e-30 104.9 0.0 1.9e-30 104.9 0.0 3.9 3 2 1 4 4 4 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 EEQ40456.1 - 4.3e-19 69.2 0.0 1.5e-18 67.4 0.0 2.0 1 0 0 1 1 1 1 NFACT protein RNA binding domain AF-4 PF05110.13 EEQ40456.1 - 0.36 8.9 47.5 0.013 13.7 12.8 2.3 2 0 0 2 2 2 0 AF-4 proto-oncoprotein His_Phos_2 PF00328.22 EEQ40457.1 - 2.6e-54 185.1 0.0 3.1e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GST_C PF00043.25 EEQ40458.1 - 2.5e-20 72.5 0.0 4.3e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EEQ40458.1 - 9.8e-19 67.5 0.0 1.8e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EEQ40458.1 - 1.2e-11 44.8 0.0 2.3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EEQ40458.1 - 2.2e-10 40.7 0.0 4.5e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EEQ40458.1 - 0.00013 22.1 0.0 0.00047 20.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ40458.1 - 0.043 13.9 0.0 0.086 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GATase PF00117.28 EEQ40459.1 - 5.6e-08 32.8 0.0 9.7e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase class-I CREPT PF16566.5 EEQ40460.1 - 0.16 12.1 13.2 1.2 9.3 2.0 3.0 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PKcGMP_CC PF16808.5 EEQ40460.1 - 0.89 9.5 4.0 21 5.1 0.2 3.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_2 PF07716.15 EEQ40460.1 - 4 7.6 8.0 1.7 8.8 2.7 3.1 2 0 0 2 2 2 0 Basic region leucine zipper CorA PF01544.18 EEQ40460.1 - 7.9 5.7 12.3 0.38 10.0 5.9 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1072 PF06380.11 EEQ40461.1 - 1.5 8.8 9.4 2.3 8.1 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1072) Cyt-b5 PF00173.28 EEQ40462.1 - 4.6e-10 39.5 0.1 6.8e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Flavi_M PF01004.19 EEQ40462.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M AbiJ_NTD4 PF18863.1 EEQ40462.1 - 0.11 13.0 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 AbiJ N-terminal domain 4 RRM_1 PF00076.22 EEQ40463.1 - 3.7e-17 61.9 0.0 7.1e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EEQ40463.1 - 2.4e-12 47.3 4.8 2.4e-12 47.3 4.8 2.0 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Aldo_ket_red PF00248.21 EEQ40465.1 - 1.8e-42 145.6 0.2 3.8e-40 137.9 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NETI PF14044.6 EEQ40465.1 - 0.013 15.2 0.0 0.3 10.9 0.0 2.6 2 1 0 2 2 2 0 NETI protein Kri1_C PF12936.7 EEQ40467.1 - 1.4e-32 111.7 3.2 1.4e-32 111.7 3.2 4.5 4 1 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 EEQ40467.1 - 6.7e-19 68.4 10.3 6.7e-19 68.4 10.3 5.8 4 1 1 6 6 6 1 KRI1-like family YlzJ PF14035.6 EEQ40467.1 - 0.15 12.3 1.5 0.73 10.1 0.0 2.8 2 0 0 2 2 2 0 YlzJ-like protein CorA PF01544.18 EEQ40468.1 - 5.2e-42 144.2 2.7 2e-25 89.7 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Phyto_Pns9_10 PF05878.11 EEQ40468.1 - 0.17 11.0 0.6 0.42 9.7 0.2 1.8 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 Corona_I PF03187.14 EEQ40469.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Corona nucleocapsid I protein Coprogen_oxidas PF01218.18 EEQ40470.1 - 1.5e-95 319.3 0.1 1.7e-95 319.2 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase XLF PF09302.11 EEQ40471.1 - 2.9e-14 53.6 0.0 5.5e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Pex19 PF04614.12 EEQ40471.1 - 0.13 12.0 0.1 0.22 11.2 0.1 1.3 1 0 0 1 1 1 0 Pex19 protein family PRK PF00485.18 EEQ40472.1 - 3.3e-10 40.0 0.0 4.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EEQ40472.1 - 2.5e-06 28.1 0.5 2.1e-05 25.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EEQ40472.1 - 2.8e-06 27.5 0.0 0.0014 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EEQ40472.1 - 6.5e-06 25.3 0.0 9.6e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 EEQ40472.1 - 3e-05 24.4 0.0 5.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 EEQ40472.1 - 9.8e-05 21.9 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.6 EEQ40472.1 - 0.00035 21.0 0.7 0.027 14.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EEQ40472.1 - 0.00055 20.2 0.0 0.00095 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EEQ40472.1 - 0.00058 20.1 0.0 0.00094 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EEQ40472.1 - 0.00058 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 EEQ40472.1 - 0.0028 17.6 0.0 0.004 17.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain ABC_tran PF00005.27 EEQ40472.1 - 0.0034 17.9 0.0 0.004 17.7 0.0 1.4 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EEQ40472.1 - 0.0042 17.0 0.1 0.0063 16.5 0.1 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain NTPase_1 PF03266.15 EEQ40472.1 - 0.0042 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 NTPase MMR_HSR1 PF01926.23 EEQ40472.1 - 0.0047 17.0 0.0 0.0085 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ40472.1 - 0.0079 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 RsgA GTPase MobB PF03205.14 EEQ40472.1 - 0.008 16.1 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 EEQ40472.1 - 0.0097 15.7 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Thymidylate_kin PF02223.17 EEQ40472.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 2 0 0 2 2 1 0 Thymidylate kinase 6PF2K PF01591.18 EEQ40472.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase dNK PF01712.19 EEQ40472.1 - 0.015 15.2 0.1 0.12 12.2 0.0 2.3 3 0 0 3 3 2 0 Deoxynucleoside kinase ATPase_2 PF01637.18 EEQ40472.1 - 0.021 14.7 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EEQ40472.1 - 0.022 13.9 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 EEQ40472.1 - 0.024 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DnaB_C PF03796.15 EEQ40472.1 - 0.025 13.9 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DUF87 PF01935.17 EEQ40472.1 - 0.027 14.6 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_14 PF13173.6 EEQ40472.1 - 0.032 14.3 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EEQ40472.1 - 0.036 13.8 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EEQ40472.1 - 0.039 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 EEQ40472.1 - 0.048 13.6 0.0 0.08 12.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EEQ40472.1 - 0.055 13.9 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Ploopntkinase3 PF18751.1 EEQ40472.1 - 0.055 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 cobW PF02492.19 EEQ40472.1 - 0.06 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EEQ40472.1 - 0.078 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ40472.1 - 0.08 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Arf PF00025.21 EEQ40472.1 - 0.099 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_29 PF13555.6 EEQ40472.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 EEQ40472.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EEQ40472.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PIN_4 PF13638.6 EEQ40473.1 - 2e-31 109.0 0.4 2e-31 109.0 0.4 1.9 2 0 0 2 2 2 1 PIN domain T4_Rnl2_C PF18043.1 EEQ40473.1 - 0.036 14.2 1.0 13 6.0 0.0 3.4 3 0 0 3 3 3 0 T4 RNA ligase 2 C-terminal DUF155 PF02582.14 EEQ40474.1 - 8.4e-56 188.8 0.6 1.9e-55 187.7 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 DUF5450 PF17529.2 EEQ40474.1 - 0.0054 16.9 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5450) tRNA-synt_1c PF00749.21 EEQ40475.1 - 3.1e-115 384.4 0.0 4.3e-115 383.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EEQ40475.1 - 5.3e-39 133.9 0.5 5.3e-39 133.9 0.5 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 EEQ40475.1 - 1.5e-13 50.9 0.6 1.5e-13 50.9 0.6 2.5 2 0 0 2 2 2 1 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 EEQ40475.1 - 1.5e-05 25.1 0.1 6.7e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EEQ40475.1 - 0.00023 21.1 0.0 0.00074 19.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Methyltransf_25 PF13649.6 EEQ40476.1 - 7.6e-15 55.4 0.0 1.7e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ40476.1 - 9.1e-14 51.9 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ40476.1 - 6.6e-11 42.0 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EEQ40476.1 - 1.6e-05 25.6 0.0 3.3e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EEQ40476.1 - 2.9e-05 23.3 0.0 5.3e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.6 EEQ40476.1 - 0.00011 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ40476.1 - 0.0027 17.5 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EEQ40476.1 - 0.016 14.9 0.0 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_8 PF05148.15 EEQ40476.1 - 0.021 14.7 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase SBDS PF01172.18 EEQ40477.1 - 8.7e-23 80.2 0.1 9.5e-23 80.1 0.1 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Tcf25 PF04910.14 EEQ40478.1 - 1.6e-91 307.0 3.7 2.3e-91 306.5 3.7 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF5112 PF17139.4 EEQ40478.1 - 0.026 14.0 0.2 0.067 12.7 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5112) TPR_14 PF13428.6 EEQ40478.1 - 0.06 14.2 0.1 3.1 8.9 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Aldedh PF00171.22 EEQ40479.1 - 8.4e-128 426.8 0.0 1.1e-127 426.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family V-ATPase_G PF03179.15 EEQ40480.1 - 4.1e-30 104.4 17.3 4.5e-30 104.3 17.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit vATP-synt_E PF01991.18 EEQ40480.1 - 0.0035 16.8 14.2 0.0046 16.4 14.2 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit PilJ PF13675.6 EEQ40480.1 - 0.014 15.4 0.6 0.017 15.1 0.6 1.1 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term ATP-synt_B PF00430.18 EEQ40480.1 - 0.021 14.9 9.6 0.021 14.9 9.6 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 EEQ40480.1 - 0.022 15.1 17.1 0.025 15.0 17.1 1.1 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit RE_AlwI PF09491.10 EEQ40480.1 - 0.027 13.3 6.9 0.035 12.9 6.9 1.3 1 1 0 1 1 1 0 AlwI restriction endonuclease Mst1_SARAH PF11629.8 EEQ40480.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.1 2 1 1 3 3 3 0 C terminal SARAH domain of Mst1 DUF16 PF01519.16 EEQ40480.1 - 0.057 13.9 8.0 0.054 14.0 7.2 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3552 PF12072.8 EEQ40480.1 - 1.4 8.2 20.5 3.3 7.1 20.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4407 PF14362.6 EEQ40480.1 - 2.2 7.6 9.3 1.3 8.3 7.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Helicase_C PF00271.31 EEQ40481.1 - 1.9e-19 70.0 0.0 3.5e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EEQ40482.1 - 2.2e-39 135.2 1.0 3.4e-39 134.6 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EEQ40482.1 - 0.0016 18.4 0.1 0.026 14.5 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PH_12 PF16457.5 EEQ40482.1 - 0.028 14.9 0.5 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain AAA_14 PF13173.6 EEQ40482.1 - 0.044 13.8 0.0 0.34 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain SNF2_N PF00176.23 EEQ40483.1 - 5.4e-19 68.1 0.0 1.6e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.13 EEQ40483.1 - 1.3e-12 47.8 8.3 1.3e-12 47.8 8.3 2.8 2 1 1 3 3 3 1 HSA ResIII PF04851.15 EEQ40483.1 - 0.00024 21.1 0.0 0.00024 21.1 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit MotY_N PF18393.1 EEQ40483.1 - 0.16 12.1 1.3 0.32 11.1 1.3 1.4 1 0 0 1 1 1 0 MotY N-terminal domain FliL PF03748.14 EEQ40483.1 - 0.22 12.1 2.0 0.57 10.8 0.9 2.1 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL Tugs PF17840.1 EEQ40483.1 - 1.2 9.4 11.1 0.4 10.9 0.8 3.4 3 1 1 4 4 4 0 Tethering Ubl4a to BAGS domain PAS_7 PF12860.7 EEQ40483.1 - 4.4 7.5 5.9 2.1 8.5 2.0 2.4 1 1 1 2 2 2 0 PAS fold DUF1374 PF07118.11 EEQ40484.1 - 0.064 13.8 0.4 0.13 12.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) NDUF_B8 PF05821.11 EEQ40485.1 - 1.3e-06 28.4 0.1 2e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) RRM_1 PF00076.22 EEQ40487.1 - 4.8e-29 100.0 0.0 5.7e-14 51.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.6 EEQ40488.1 - 2.9e-18 65.4 1.7 6.6e-18 64.2 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EEQ40488.1 - 1.2e-13 50.7 0.8 1.9e-13 50.1 0.8 1.3 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EEQ40488.1 - 0.00089 19.3 0.1 0.0023 18.0 0.1 1.7 1 0 0 1 1 1 1 G-patch domain DUF4303 PF14136.6 EEQ40488.1 - 0.14 11.9 5.0 0.074 12.8 2.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4303) Med4 PF10018.9 EEQ40489.1 - 2e-27 96.2 4.9 3.1e-27 95.5 4.9 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 IMD PF08397.11 EEQ40489.1 - 0.011 15.1 1.1 0.02 14.3 1.1 1.4 1 0 0 1 1 1 0 IRSp53/MIM homology domain TORC_N PF12884.7 EEQ40489.1 - 0.57 11.0 3.8 1.3 9.9 0.0 3.1 3 0 0 3 3 3 0 Transducer of regulated CREB activity, N terminus TMPIT PF07851.13 EEQ40489.1 - 2.3 7.4 4.1 1.1 8.4 1.0 1.9 1 1 1 2 2 2 0 TMPIT-like protein Ferrochelatase PF00762.19 EEQ40490.1 - 3e-97 325.5 0.0 3.5e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MBOAT PF03062.19 EEQ40491.1 - 2.2e-59 201.6 10.1 6.2e-59 200.1 10.1 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Cnd1 PF12717.7 EEQ40492.1 - 9.1e-47 159.1 7.3 1.2e-41 142.5 0.5 4.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EEQ40492.1 - 3.4e-35 121.3 0.3 1.1e-34 119.7 0.3 2.0 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 EEQ40492.1 - 1.5e-10 40.4 4.8 0.06 13.6 0.0 7.1 7 0 0 7 7 7 3 HEAT repeat Cnd3 PF12719.7 EEQ40492.1 - 1.6e-07 30.9 11.1 6.9e-07 28.7 2.3 3.8 3 2 0 3 3 3 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EEQ40492.1 - 2.2e-07 31.1 0.0 0.021 15.2 0.0 3.4 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EEQ40492.1 - 3.5e-05 24.2 0.1 0.69 10.5 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat RTP1_C1 PF10363.9 EEQ40492.1 - 0.0037 17.4 0.6 1.3 9.3 0.0 3.4 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 SapB_2 PF03489.17 EEQ40492.1 - 4.9 7.4 5.6 5.9 7.1 0.0 3.8 4 0 0 4 4 4 0 Saposin-like type B, region 2 TAF4 PF05236.14 EEQ40494.1 - 1.2e-69 235.2 3.2 1.2e-69 235.2 3.2 1.7 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family TFIID_20kDa PF03847.13 EEQ40494.1 - 0.094 13.2 0.0 0.18 12.3 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RTC PF01137.21 EEQ40495.1 - 4.1e-42 143.9 0.0 5e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EEQ40495.1 - 1.5e-30 105.7 0.0 2.4e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PI3_PI4_kinase PF00454.27 EEQ40496.1 - 1.2e-71 241.5 0.1 3e-71 240.2 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EEQ40496.1 - 1e-42 144.6 2.7 2e-42 143.6 0.5 2.3 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 EEQ40496.1 - 6.7e-17 61.0 0.4 1.4e-16 60.0 0.4 1.6 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EEQ40496.1 - 5.5e-10 39.0 0.2 8e-10 38.4 0.2 1.3 1 0 0 1 1 1 1 FAT domain FAT PF02259.23 EEQ40497.1 - 8.3e-131 436.3 3.3 9.6e-131 436.1 1.8 1.6 2 0 0 2 2 2 1 FAT domain TPR_19 PF14559.6 EEQ40497.1 - 0.00049 20.6 0.0 0.52 10.9 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ40497.1 - 0.093 13.6 1.6 21 6.2 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ40497.1 - 0.15 12.4 0.1 3.1 8.1 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3385 PF11865.8 EEQ40499.1 - 2.4e-72 242.1 6.9 2e-63 213.1 0.4 6.2 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 EEQ40499.1 - 9.6e-15 54.8 0.2 0.022 15.1 0.0 7.7 5 2 5 10 10 10 4 HEAT repeats HEAT PF02985.22 EEQ40499.1 - 5.7e-14 51.0 4.6 0.0027 17.8 0.0 9.1 11 0 0 11 11 9 3 HEAT repeat HEAT_EZ PF13513.6 EEQ40499.1 - 3.1e-13 49.9 0.7 0.0029 18.1 0.1 8.1 7 1 2 9 9 8 4 HEAT-like repeat Cnd1 PF12717.7 EEQ40499.1 - 0.00014 21.9 4.4 0.00088 19.3 0.3 4.0 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EEQ40499.1 - 0.00017 20.9 0.6 0.54 9.4 0.1 4.5 3 1 1 5 5 5 1 Nuclear condensing complex subunits, C-term domain IFRD PF05004.13 EEQ40499.1 - 0.00023 20.4 4.8 0.03 13.5 0.1 4.2 3 2 2 5 5 5 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 EEQ40499.1 - 0.0013 18.4 2.8 30 4.1 0.0 6.5 5 2 2 7 7 7 0 CLASP N terminal RTP1_C1 PF10363.9 EEQ40499.1 - 0.0015 18.7 0.3 6.2 7.0 0.0 4.7 4 2 2 6 6 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Dopey_N PF04118.14 EEQ40499.1 - 0.0026 16.9 15.7 0.58 9.2 0.1 5.5 4 1 2 6 6 6 2 Dopey, N-terminal RICTOR_V PF14668.6 EEQ40499.1 - 0.0034 17.6 0.1 5.8 7.2 0.0 4.7 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.7 EEQ40499.1 - 0.017 15.7 8.0 17 6.1 0.0 7.5 7 2 3 10 10 9 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 EEQ40499.1 - 0.02 14.8 2.9 11 5.9 0.1 4.8 4 1 0 4 4 4 0 Myosin-binding striated muscle assembly central RICTOR_N PF14664.6 EEQ40499.1 - 0.064 12.2 2.0 3.7 6.4 0.1 3.8 2 2 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term Cohesin_HEAT PF12765.7 EEQ40499.1 - 0.073 13.4 0.5 5.8 7.3 0.2 3.8 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.8 EEQ40499.1 - 0.13 12.2 0.2 1.8 8.5 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Tti2 PF10521.9 EEQ40499.1 - 7.9 5.9 9.6 33 3.9 0.0 4.8 3 1 2 5 5 5 0 Tti2 family Actin PF00022.19 EEQ40500.1 - 3.2e-91 306.0 0.0 4.2e-54 183.7 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 EEQ40500.1 - 0.00078 19.8 0.0 0.01 16.2 0.0 2.5 2 1 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 EEQ40500.1 - 0.00091 18.1 0.0 0.33 9.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Cpn60_TCP1 PF00118.24 EEQ40501.1 - 5.2e-152 506.9 7.4 6e-152 506.7 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_ATPase PF13246.6 EEQ40501.1 - 0.017 15.2 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Enolase_N PF03952.16 EEQ40501.1 - 0.25 11.5 2.0 57 3.9 0.1 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain Jag_N PF14804.6 EEQ40501.1 - 0.61 10.5 3.0 11 6.5 0.0 3.2 3 0 0 3 3 3 0 Jag N-terminus HEAT_2 PF13646.6 EEQ40502.1 - 6.4e-29 100.2 0.2 8.3e-13 48.5 0.0 3.0 2 1 1 3 3 3 2 HEAT repeats HEAT_PBS PF03130.16 EEQ40502.1 - 1.2e-16 59.6 0.0 6e-05 23.3 0.0 6.2 6 0 0 6 6 6 3 PBS lyase HEAT-like repeat HEAT PF02985.22 EEQ40502.1 - 1.1e-11 43.9 0.5 0.24 11.7 0.0 6.4 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 EEQ40502.1 - 1.4e-07 31.8 0.1 1.8 9.2 0.0 4.7 4 1 0 4 4 4 2 HEAT-like repeat DUF3385 PF11865.8 EEQ40502.1 - 0.042 13.7 0.0 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TFIIS_C PF01096.18 EEQ40503.1 - 7.1e-18 64.2 1.5 7.1e-18 64.2 1.5 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EEQ40503.1 - 1.4e-08 34.4 7.1 1.1e-05 25.1 0.4 3.0 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit DZR PF12773.7 EEQ40503.1 - 0.00019 21.4 6.5 0.049 13.7 0.3 2.7 2 1 0 2 2 2 2 Double zinc ribbon C1_1 PF00130.22 EEQ40503.1 - 0.0005 19.9 3.5 0.0083 16.0 0.2 2.4 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4_Topoisom PF01396.19 EEQ40503.1 - 0.015 15.1 5.3 0.084 12.7 3.0 2.9 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-TFIIB PF13453.6 EEQ40503.1 - 0.015 14.6 0.7 0.015 14.6 0.7 2.4 3 0 0 3 3 2 0 Transcription factor zinc-finger zinc_ribbon_2 PF13240.6 EEQ40503.1 - 0.017 14.8 13.1 0.29 10.9 0.3 3.5 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 EEQ40503.1 - 0.025 14.6 7.2 6.5 6.8 7.7 2.9 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Baculo_LEF5_C PF11792.8 EEQ40503.1 - 0.028 14.1 2.1 0.26 11.0 0.0 2.6 3 0 0 3 3 2 0 Baculoviridae late expression factor 5 C-terminal domain TF_Zn_Ribbon PF08271.12 EEQ40503.1 - 0.028 13.9 11.3 0.063 12.8 3.1 2.8 2 2 0 2 2 2 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EEQ40503.1 - 0.034 13.6 8.6 1.8 8.1 0.6 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EEQ40503.1 - 0.035 14.2 10.7 3.6 7.8 0.1 3.4 3 0 0 3 3 3 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 EEQ40503.1 - 0.039 13.9 0.7 0.039 13.9 0.7 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Elf1 PF05129.13 EEQ40503.1 - 0.19 11.8 6.1 2.5 8.2 0.4 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2072 PF09845.9 EEQ40503.1 - 0.28 11.4 0.1 0.28 11.4 0.1 2.5 1 1 1 3 3 3 0 Zn-ribbon containing protein RecR PF02132.15 EEQ40503.1 - 0.31 10.7 3.3 2.6 7.7 0.6 2.5 2 0 0 2 2 2 0 RecR protein zf-RING_7 PF02591.15 EEQ40503.1 - 0.35 11.1 6.3 1e+02 3.2 0.1 4.1 4 0 0 4 4 4 0 C4-type zinc ribbon domain Nop10p PF04135.12 EEQ40503.1 - 0.37 10.9 2.7 0.43 10.7 0.2 2.3 2 1 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Paired_CXXCH_1 PF09699.10 EEQ40503.1 - 0.4 10.5 0.0 0.4 10.5 0.0 2.7 3 1 0 3 3 2 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-C2H2 PF00096.26 EEQ40503.1 - 0.54 10.8 17.0 0.56 10.8 1.5 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zinc-ribbons_6 PF07191.12 EEQ40503.1 - 0.61 10.1 7.7 6 6.9 0.5 2.6 2 2 0 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 EEQ40503.1 - 1.2 9.2 7.1 4.6 7.3 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain Mu-like_Com PF10122.9 EEQ40503.1 - 1.4 8.5 5.8 4.3 6.9 0.0 3.0 2 1 1 3 3 3 0 Mu-like prophage protein Com Lar_restr_allev PF14354.6 EEQ40503.1 - 1.4 9.3 7.1 0.9 10.0 0.7 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF3797 PF12677.7 EEQ40503.1 - 1.5 8.8 5.3 1.8 8.5 1.9 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3797) GATA PF00320.27 EEQ40503.1 - 1.7 8.3 7.9 1.4 8.5 0.4 3.1 3 1 0 3 3 3 0 GATA zinc finger zinc_ribbon_13 PF09855.9 EEQ40503.1 - 2.4 8.4 9.2 24 5.2 5.3 3.1 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Nudix_N_2 PF14803.6 EEQ40503.1 - 2.9 7.9 10.1 9 6.3 1.6 3.4 2 2 0 2 2 2 0 Nudix N-terminal zf-C2H2_4 PF13894.6 EEQ40503.1 - 3.5 8.7 11.5 21 6.3 0.6 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zinc_ribbon_15 PF17032.5 EEQ40503.1 - 3.9 8.3 10.5 0.81 10.5 1.7 3.0 1 1 2 3 3 3 0 zinc-ribbon family NOB1_Zn_bind PF08772.11 EEQ40503.1 - 5.3 7.3 11.3 1.2 9.4 0.1 3.1 2 2 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ogr_Delta PF04606.12 EEQ40503.1 - 5.6 7.0 10.3 0.2 11.6 3.9 2.0 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Zn_ribbon_recom PF13408.6 EEQ40503.1 - 7.9 7.1 10.7 6.3 7.4 1.6 3.2 2 2 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-H2C2_2 PF13465.6 EEQ40503.1 - 8.1 7.1 9.0 3.6 8.2 0.0 3.3 4 0 0 4 4 3 0 Zinc-finger double domain Cytochrome_C7 PF14522.6 EEQ40503.1 - 8.2 6.5 9.5 1.2e+02 2.8 9.6 2.6 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c CpXC PF14353.6 EEQ40503.1 - 8.9 6.4 8.8 1.5 8.9 1.0 2.8 1 1 2 3 3 3 0 CpXC protein OrfB_Zn_ribbon PF07282.11 EEQ40503.1 - 9.7 6.2 8.0 38 4.3 2.8 2.7 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Fcf1 PF04900.12 EEQ40504.1 - 5.2e-33 113.4 0.1 9.6e-33 112.5 0.1 1.5 1 0 0 1 1 1 1 Fcf1 SRP-alpha_N PF04086.13 EEQ40504.1 - 0.0025 17.8 12.1 0.0038 17.2 12.1 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal DUF1152 PF06626.12 EEQ40504.1 - 0.11 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Pal1 PF08316.11 EEQ40504.1 - 3.8 8.3 8.5 5.5 7.7 0.0 2.8 2 1 0 2 2 2 0 Pal1 cell morphology protein R3H PF01424.22 EEQ40505.1 - 6e-21 74.2 0.0 1.3e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain SPG48 PF14764.6 EEQ40505.1 - 0.085 13.3 0.5 20 5.7 0.0 2.7 2 0 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking GT-D PF08759.11 EEQ40505.1 - 0.72 9.5 3.2 1.5 8.4 0.8 2.3 1 1 1 2 2 2 0 Glycosyltransferase GT-D fold OrfB_Zn_ribbon PF07282.11 EEQ40506.1 - 4.7 7.2 13.0 2.6 8.0 3.4 2.7 1 1 2 3 3 3 0 Putative transposase DNA-binding domain Pkinase PF00069.25 EEQ40507.1 - 1.3e-69 234.6 0.0 2.3e-69 233.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40507.1 - 6.9e-41 140.2 0.0 1.3e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ40507.1 - 8.7e-09 35.1 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ40507.1 - 0.0046 16.3 0.0 0.0092 15.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ40507.1 - 0.0081 16.1 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Nucleo_P87 PF07267.11 EEQ40507.1 - 1.9 7.3 11.4 4.9 5.9 11.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HEAT_2 PF13646.6 EEQ40508.1 - 2.3e-05 24.7 0.0 0.0011 19.3 0.0 3.2 4 1 0 4 4 4 1 HEAT repeats Cnd1 PF12717.7 EEQ40508.1 - 0.00014 22.0 1.9 0.00014 22.0 1.9 3.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EEQ40508.1 - 0.0002 21.3 0.2 1.3 9.5 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat VHS PF00790.19 EEQ40508.1 - 0.0052 16.6 5.4 5.9 6.7 0.1 4.8 5 1 0 5 5 5 2 VHS domain Vac14_Fab1_bd PF12755.7 EEQ40508.1 - 0.076 13.6 0.1 0.56 10.8 0.1 2.6 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EEQ40509.1 - 0.0025 17.9 0.9 0.011 15.8 0.2 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EEQ40509.1 - 0.11 13.1 0.2 0.7 10.5 0.0 2.4 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region GLE1 PF07817.13 EEQ40510.1 - 1.7e-77 260.0 3.3 1.7e-77 260.0 3.3 1.9 2 0 0 2 2 2 1 GLE1-like protein DUF2514 PF10721.9 EEQ40510.1 - 1.9 8.5 23.4 5.5 7.0 23.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) Ribosomal_L5_C PF00673.21 EEQ40511.1 - 1e-29 102.5 0.0 1.6e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EEQ40511.1 - 0.00045 20.5 0.0 0.0012 19.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 DUF2439 PF10382.9 EEQ40512.1 - 2.2e-19 69.6 0.0 3.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Cyclin PF08613.11 EEQ40513.1 - 6.3e-37 127.4 0.1 1.6e-36 126.1 0.1 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EEQ40513.1 - 0.0034 17.1 0.1 0.0061 16.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Metallophos PF00149.28 EEQ40514.1 - 3.5e-39 135.4 1.9 4.4e-39 135.1 1.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EEQ40514.1 - 4e-16 59.2 0.1 7.5e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF4711 PF15829.5 EEQ40514.1 - 0.13 12.2 2.6 0.21 11.5 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) MoCF_biosynth PF00994.24 EEQ40515.1 - 1.3e-29 102.7 0.1 2.8e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain Chordopox_A13L PF05961.11 EEQ40515.1 - 0.0048 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Chordopoxvirus A13L protein tRNA-synt_2c PF01411.19 EEQ40516.1 - 8.9e-227 754.0 0.0 8.9e-227 754.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EEQ40516.1 - 3.7e-19 68.6 0.2 1e-18 67.2 0.2 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EEQ40516.1 - 8.2e-15 55.4 5.2 8.2e-15 55.4 5.2 2.4 3 0 0 3 3 3 1 DHHA1 domain Peptidase_C58 PF03543.14 EEQ40516.1 - 0.043 13.5 1.2 0.096 12.4 1.2 1.5 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen Copper-fist PF00649.18 EEQ40517.1 - 1.5e-18 66.0 1.6 1.5e-18 66.0 1.6 2.1 2 0 0 2 2 2 1 Copper fist DNA binding domain HSF_DNA-bind PF00447.17 EEQ40518.1 - 5.1e-30 103.9 2.9 5.1e-30 103.9 2.9 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding NtCtMGAM_N PF16863.5 EEQ40519.1 - 0.027 14.7 5.2 0.44 10.8 0.1 3.7 4 0 0 4 4 4 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF5633 PF18656.1 EEQ40519.1 - 0.16 11.9 2.2 0.16 11.9 0.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Ribosomal_L1 PF00687.21 EEQ40520.1 - 1.2e-37 129.6 3.4 1.2e-37 129.6 3.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family BHD_2 PF10404.9 EEQ40520.1 - 5.5 8.0 8.4 5.2 8.1 5.6 2.5 2 1 0 2 2 2 0 Rad4 beta-hairpin domain 2 Calcipressin PF04847.12 EEQ40521.1 - 9.3e-11 41.8 0.2 1.6e-10 41.0 0.2 1.4 1 1 0 1 1 1 1 Calcipressin Lipase_3 PF01764.25 EEQ40522.1 - 9.1e-28 96.9 0.0 1.3e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EEQ40522.1 - 0.00035 21.3 0.0 0.00042 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EEQ40522.1 - 0.00082 19.2 0.1 0.0028 17.4 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Esterase PF00756.20 EEQ40522.1 - 0.0009 18.9 0.1 0.0017 18.1 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EEQ40522.1 - 0.022 14.1 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ40522.1 - 0.068 12.8 0.1 0.094 12.3 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EEQ40522.1 - 0.22 11.6 0.1 0.34 11.0 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain Tht1 PF04163.12 EEQ40523.1 - 1.4e-30 106.6 15.9 1.8e-30 106.2 15.9 1.1 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein DegS PF05384.11 EEQ40523.1 - 9.6e-05 21.9 1.0 0.075 12.5 0.0 2.7 1 1 0 2 2 2 2 Sensor protein DegS TBK1_CCD1 PF18394.1 EEQ40523.1 - 0.00035 20.2 1.0 0.13 11.8 0.1 2.5 2 1 0 2 2 2 2 TANK-binding kinase 1 coiled-coil domain 1 DUF3418 PF11898.8 EEQ40523.1 - 0.0046 15.7 1.5 0.052 12.2 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3418) CdvA PF18822.1 EEQ40523.1 - 0.0061 16.4 1.8 2.1 8.2 0.0 2.9 2 1 0 2 2 2 2 CdvA-like coiled-coil domain Cluap1 PF10234.9 EEQ40523.1 - 0.01 15.3 5.4 0.018 14.4 1.7 2.3 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF2937 PF11157.8 EEQ40523.1 - 0.034 13.9 0.2 0.088 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) DUF5082 PF16888.5 EEQ40523.1 - 0.089 13.1 6.8 1.5 9.1 0.4 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) LOH1CR12 PF10158.9 EEQ40523.1 - 0.15 12.1 1.9 7.7 6.6 0.3 3.4 3 1 0 3 3 3 0 Tumour suppressor protein Baculo_PEP_C PF04513.12 EEQ40523.1 - 0.16 12.0 10.6 1.8 8.6 2.8 2.8 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MRP-S23 PF10484.9 EEQ40523.1 - 0.53 10.5 4.8 0.17 12.2 0.3 2.4 3 0 0 3 3 3 0 Mitochondrial ribosomal protein S23 NPV_P10 PF05531.12 EEQ40523.1 - 0.74 10.3 2.9 16 6.0 0.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MnmE_helical PF12631.7 EEQ40523.1 - 1.4 9.0 4.1 1 9.5 1.6 2.2 1 1 1 2 2 2 0 MnmE helical domain DUF948 PF06103.11 EEQ40523.1 - 1.7 9.0 4.7 4.4 7.6 0.6 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Mce4_CUP1 PF11887.8 EEQ40523.1 - 2.1 7.7 3.7 1.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative SUR7 PF06687.12 EEQ40525.1 - 7.3e-30 104.2 7.2 9.7e-30 103.8 7.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2721 PF11026.8 EEQ40525.1 - 0.016 15.1 1.1 0.016 15.1 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF5516 PF17637.2 EEQ40525.1 - 1.8 8.3 4.9 3.6 7.4 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5516) Inositol_P PF00459.25 EEQ40526.1 - 2.1e-53 181.6 0.2 7e-53 179.9 0.2 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family tRNA-synt_1b PF00579.25 EEQ40527.1 - 7.6e-73 245.4 0.0 1.1e-72 244.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EEQ40527.1 - 0.0048 16.7 0.1 0.022 14.6 0.1 2.1 1 1 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain HA2 PF04408.23 EEQ40528.1 - 2.8e-18 66.2 1.2 6.6e-18 65.0 0.0 2.4 3 1 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EEQ40528.1 - 2.7e-14 53.4 1.3 4.3e-13 49.6 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EEQ40528.1 - 3.7e-09 36.8 0.0 9.9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EEQ40528.1 - 1.3e-08 34.8 0.2 3.4e-08 33.5 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ40528.1 - 3.3e-06 27.4 0.1 7.3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EEQ40528.1 - 0.005 16.5 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EEQ40528.1 - 0.0076 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EEQ40528.1 - 0.013 16.1 0.3 0.013 16.1 0.3 3.5 2 1 1 3 3 2 0 AAA domain AAA_19 PF13245.6 EEQ40528.1 - 0.017 15.5 0.1 0.033 14.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EEQ40528.1 - 0.026 14.5 0.0 0.075 12.9 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase Ploopntkinase3 PF18751.1 EEQ40528.1 - 0.044 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_7 PF12775.7 EEQ40528.1 - 0.049 13.1 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EEQ40528.1 - 0.052 13.3 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ40528.1 - 0.14 11.5 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EEQ40528.1 - 0.17 12.4 0.2 0.17 12.4 0.2 3.0 2 1 1 3 3 3 0 ABC transporter PIG-Y PF15159.6 EEQ40529.1 - 8.7e-06 26.6 21.4 6.2e-05 23.8 21.4 2.0 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Transglut_core PF01841.19 EEQ40530.1 - 3.9e-07 30.5 0.0 8.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Rad4 PF03835.15 EEQ40530.1 - 4e-07 29.8 0.4 4.7e-06 26.4 0.0 2.2 1 1 1 2 2 2 1 Rad4 transglutaminase-like domain PAW PF04721.17 EEQ40530.1 - 0.058 13.2 0.5 0.11 12.3 0.5 1.5 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW DUF1033 PF06279.11 EEQ40530.1 - 0.086 13.0 2.3 1.3 9.2 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1033) Zn_Tnp_IS1595 PF12760.7 EEQ40530.1 - 0.15 12.1 4.1 0.68 10.0 4.1 2.1 1 1 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_9 PF14369.6 EEQ40530.1 - 0.61 10.4 3.8 1.1 9.6 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon Alg6_Alg8 PF03155.15 EEQ40531.1 - 1.4e-137 459.6 26.3 1.9e-137 459.2 26.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Peptidase_M56 PF05569.11 EEQ40532.1 - 0.079 12.1 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 2OG-FeII_Oxy_2 PF13532.6 EEQ40534.1 - 9.5e-34 117.3 0.0 1.4e-33 116.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EEQ40534.1 - 0.00015 21.8 4.6 0.00027 21.0 4.6 1.4 1 0 0 1 1 1 1 GRF zinc finger APG6 PF04111.12 EEQ40535.1 - 5.9e-50 169.7 2.5 1.1e-49 168.8 0.1 2.4 2 1 1 3 3 3 1 Apg6 BARA domain APG6_N PF17675.1 EEQ40535.1 - 1e-20 74.6 15.1 2.1e-20 73.6 15.1 1.6 1 0 0 1 1 1 1 Apg6 coiled-coil region SusD-like PF12741.7 EEQ40535.1 - 0.031 13.2 2.6 0.054 12.4 1.5 1.9 2 0 0 2 2 2 0 Susd and RagB outer membrane lipoprotein EDS1_EP PF18117.1 EEQ40535.1 - 0.032 14.7 1.6 0.063 13.7 1.6 1.5 1 0 0 1 1 1 0 Enhanced disease susceptibility 1 protein EP domain RasGAP_C PF03836.15 EEQ40535.1 - 0.072 13.2 8.7 0.18 11.9 8.6 1.8 1 1 0 1 1 1 0 RasGAP C-terminus Phage_GP20 PF06810.11 EEQ40535.1 - 0.14 12.0 7.8 0.36 10.6 7.8 1.7 1 0 0 1 1 1 0 Phage minor structural protein GP20 Yippee-Mis18 PF03226.14 EEQ40535.1 - 0.14 12.4 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Atg14 PF10186.9 EEQ40535.1 - 1.5 7.8 9.7 31 3.5 9.4 2.4 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF848 PF05852.11 EEQ40535.1 - 4 7.6 6.8 3.9 7.6 3.1 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FliD_N PF02465.18 EEQ40535.1 - 5.3 7.8 8.4 12 6.6 5.6 2.7 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus FapA PF03961.13 EEQ40535.1 - 6.8 5.2 6.0 14 4.2 5.8 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A Zn_clus PF00172.18 EEQ40536.1 - 0.00044 20.3 11.4 0.0011 19.0 11.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EMP70 PF02990.16 EEQ40537.1 - 2.3e-80 270.7 0.7 3e-80 270.4 0.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.16 EEQ40538.1 - 1.1e-101 341.0 38.5 2e-101 340.2 38.5 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Zn_clus PF00172.18 EEQ40541.1 - 2.8e-09 37.0 11.0 4.1e-09 36.4 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHHC PF01529.20 EEQ40542.1 - 1.2e-22 80.5 10.6 1.2e-22 80.5 10.6 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1772 PF08592.11 EEQ40542.1 - 0.33 11.3 4.6 2.7 8.3 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2569 PF10754.9 EEQ40542.1 - 1.2 9.6 9.1 0.15 12.5 3.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Fungal_trans_2 PF11951.8 EEQ40543.1 - 2.3e-22 79.4 2.0 3.6e-22 78.7 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ40543.1 - 4.4e-10 39.5 7.3 1.1e-09 38.2 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2405 PF10293.9 EEQ40543.1 - 0.0023 17.9 0.3 0.097 12.6 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) BTB_2 PF02214.22 EEQ40544.1 - 4.1e-08 33.5 2.7 6.7e-05 23.2 0.5 3.1 3 0 0 3 3 3 2 BTB/POZ domain Anp1 PF03452.14 EEQ40545.1 - 3.3e-54 184.0 0.0 7.8e-54 182.8 0.0 1.5 1 1 1 2 2 2 1 Anp1 Glycos_transf_2 PF00535.26 EEQ40545.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Ribosomal_S18 PF01084.20 EEQ40545.1 - 0.1 12.8 0.1 17 5.8 0.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S18 ATP-synt_C PF00137.21 EEQ40546.1 - 4.5e-26 91.0 31.8 7.4e-15 55.1 13.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C DUF3671 PF12420.8 EEQ40546.1 - 0.56 10.3 3.4 0.26 11.4 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function G0-G1_switch_2 PF15103.6 EEQ40546.1 - 3.1 8.3 4.1 0.7 10.4 0.8 1.6 2 0 0 2 2 2 0 G0/G1 switch protein 2 RPN1_C PF18051.1 EEQ40547.1 - 3.5e-25 87.8 0.1 5.9e-25 87.1 0.1 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EEQ40547.1 - 5e-09 36.2 6.9 2.6e-06 27.6 0.1 4.5 5 0 0 5 5 4 2 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EEQ40547.1 - 0.00047 20.5 0.0 0.035 14.5 0.0 3.1 3 1 1 4 4 3 1 HEAT repeats THOC2_N PF16134.5 EEQ40547.1 - 0.0045 15.7 0.6 0.006 15.3 0.6 1.1 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus BUD22 PF09073.10 EEQ40547.1 - 0.0081 15.5 6.1 0.011 15.2 6.1 1.1 1 0 0 1 1 1 1 BUD22 DUF913 PF06025.12 EEQ40547.1 - 0.015 14.3 2.1 0.022 13.8 2.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MID_MedPIWI PF18296.1 EEQ40547.1 - 0.039 13.8 1.1 0.074 12.8 0.4 1.7 2 0 0 2 2 2 0 MID domain of medPIWI Zip PF02535.22 EEQ40547.1 - 0.041 13.1 0.1 0.053 12.7 0.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.12 EEQ40547.1 - 0.11 11.8 12.0 0.17 11.2 12.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PA26 PF04636.13 EEQ40547.1 - 0.12 11.3 0.3 0.16 10.9 0.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DNA_pol_phi PF04931.13 EEQ40547.1 - 0.19 9.8 10.5 0.26 9.3 10.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi eIF-3c_N PF05470.12 EEQ40547.1 - 0.23 9.7 4.7 0.34 9.2 4.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Raftlin PF15250.6 EEQ40547.1 - 0.3 9.8 3.1 0.44 9.2 3.1 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 EEQ40547.1 - 0.32 9.7 1.4 0.47 9.2 1.4 1.2 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 EEQ40547.1 - 1.9 6.9 4.5 2.6 6.5 4.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NOA36 PF06524.12 EEQ40547.1 - 3.3 6.9 11.2 4.6 6.5 11.2 1.1 1 0 0 1 1 1 0 NOA36 protein RPN1_RPN2_N PF17781.1 EEQ40548.1 - 7.6e-112 373.7 2.9 9.8e-112 373.3 2.9 1.1 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 EEQ40548.1 - 7.7e-15 54.5 8.1 6.2e-07 29.5 0.5 5.5 5 0 0 5 5 5 3 Proteasome/cyclosome repeat SidC_N PF18219.1 EEQ40548.1 - 0.015 14.3 1.4 0.051 12.6 0.0 2.0 2 0 0 2 2 2 0 SidC N-terminal domain HEAT_2 PF13646.6 EEQ40548.1 - 0.032 14.6 0.0 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 HEAT repeats CRAL_TRIO_2 PF13716.6 EEQ40549.1 - 1.2e-16 61.1 0.3 3.8e-16 59.5 0.3 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 EEQ40549.1 - 3e-05 23.9 0.1 7.2e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain AFT PF08731.11 EEQ40550.1 - 1.7e-07 31.6 0.1 1.7e-07 31.6 0.1 2.4 2 0 0 2 2 2 1 Transcription factor AFT Med3 PF11593.8 EEQ40550.1 - 0.0034 16.6 3.3 0.0072 15.6 3.3 1.5 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal FAR1 PF03101.15 EEQ40550.1 - 0.33 11.7 7.0 0.18 12.5 2.7 2.7 2 1 0 2 2 2 0 FAR1 DNA-binding domain NicO PF03824.16 EEQ40550.1 - 1.9 7.8 5.6 3.8 6.8 5.6 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein Spermine_synth PF01564.17 EEQ40551.1 - 2.4e-56 190.2 0.2 3.9e-56 189.4 0.2 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EEQ40551.1 - 1.5e-21 76.0 0.1 2.8e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Pyr_redox_2 PF07992.14 EEQ40551.1 - 0.053 12.7 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 EEQ40552.1 - 2.6e-11 43.1 1.2 5.3e-11 42.1 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ40552.1 - 0.038 14.1 11.5 0.072 13.2 11.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EEQ40553.1 - 0.017 15.9 18.7 0.12 13.3 4.9 4.4 3 0 0 3 3 3 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 EEQ40553.1 - 0.054 13.3 0.7 0.15 11.8 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.6 EEQ40553.1 - 0.055 13.9 14.8 0.12 12.9 0.6 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 EEQ40553.1 - 0.17 11.6 6.1 0.74 9.6 6.1 2.1 1 0 0 1 1 1 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EEQ40553.1 - 2 9.0 20.3 0.046 14.2 6.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF775 PF05603.12 EEQ40554.1 - 0.12 11.9 3.8 0.071 12.6 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF775) DUF4477 PF14780.6 EEQ40554.1 - 0.24 11.0 4.1 0.27 10.8 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) TPR_8 PF13181.6 EEQ40555.1 - 5.2e-06 26.3 0.0 0.042 14.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ40555.1 - 0.0001 22.7 13.1 0.00086 19.8 0.2 4.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ40555.1 - 0.00084 19.3 0.9 3.7 7.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ40555.1 - 0.0016 18.7 0.5 0.25 11.6 0.0 3.1 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EEQ40555.1 - 0.0097 16.2 4.2 2 8.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EEQ40555.1 - 0.016 14.6 1.4 0.4 10.0 0.2 2.9 2 2 0 2 2 2 0 MalT-like TPR region TPR_1 PF00515.28 EEQ40555.1 - 0.018 14.9 0.8 12 5.9 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ40555.1 - 0.041 14.7 1.2 21 6.3 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ40555.1 - 0.048 13.3 0.2 15 5.4 0.0 3.4 2 1 1 3 3 3 0 TPR repeat TPR_6 PF13174.6 EEQ40555.1 - 2.9 8.7 4.3 18 6.2 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Cwf_Cwc_15 PF04889.12 EEQ40556.1 - 6.4e-23 81.8 22.4 1.7e-12 47.7 18.8 3.0 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein PA26 PF04636.13 EEQ40556.1 - 0.39 9.6 4.6 0.43 9.4 4.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF5320 PF17253.2 EEQ40556.1 - 0.43 11.7 3.1 0.27 12.3 1.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF4763 PF15960.5 EEQ40556.1 - 6.5 6.0 11.0 8.7 5.6 10.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4763) GIT_SHD PF08518.11 EEQ40558.1 - 1.2e-25 88.7 4.2 2.6e-13 49.3 0.8 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 EEQ40558.1 - 6.3e-08 32.7 1.0 6.3e-08 32.7 1.0 2.8 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term DUF4472 PF14739.6 EEQ40558.1 - 0.41 11.4 0.0 0.41 11.4 0.0 7.2 7 0 0 7 7 7 0 Domain of unknown function (DUF4472) Acyltransferase PF01553.21 EEQ40559.1 - 3.6e-31 107.6 0.0 5.7e-31 106.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase SPA PF08616.10 EEQ40560.1 - 3.8e-33 113.8 0.1 1.5e-32 111.9 0.1 2.1 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EEQ40560.1 - 3.5e-23 82.5 0.2 2.3e-22 79.9 0.2 2.1 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EEQ40560.1 - 2.5e-14 52.8 1.3 3.2e-13 49.1 1.3 2.2 1 1 0 1 1 1 1 Transport protein Avl9 DUF2347 PF09804.9 EEQ40560.1 - 0.0003 20.5 0.3 0.0053 16.4 0.1 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 EEQ40560.1 - 0.012 15.6 0.6 6.1 6.8 0.1 3.0 2 1 0 2 2 2 0 DENN (AEX-3) domain Ank_2 PF12796.7 EEQ40560.1 - 0.081 13.5 0.0 0.6 10.7 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) zf-H2C2_2 PF13465.6 EEQ40561.1 - 2.7e-06 27.6 1.6 0.017 15.5 0.1 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 EEQ40561.1 - 8e-05 22.3 5.3 0.00024 20.8 5.3 1.9 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EEQ40561.1 - 9e-05 22.7 3.0 9e-05 22.7 3.0 3.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ40561.1 - 0.00014 22.4 12.6 0.0085 16.8 1.8 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 EEQ40561.1 - 0.0038 17.0 3.7 0.23 11.2 0.3 2.5 2 0 0 2 2 2 2 zinc-ribbon domain zf-C2H2_7 PF15269.6 EEQ40561.1 - 0.065 13.3 2.5 0.1 12.7 1.5 1.8 1 1 0 1 1 1 0 Zinc-finger RGS PF00615.19 EEQ40562.1 - 8.7e-05 22.8 0.1 0.0036 17.6 0.0 2.4 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF3488 PF11992.8 EEQ40562.1 - 1.4 7.8 6.2 2 7.3 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) DUF2423 PF10338.9 EEQ40564.1 - 1.5e-15 57.1 9.6 1.5e-15 57.1 9.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) ABC_tran_Xtn PF12848.7 EEQ40564.1 - 0.45 10.6 10.3 0.65 10.1 10.3 1.4 1 0 0 1 1 1 0 ABC transporter Borrelia_P83 PF05262.11 EEQ40564.1 - 2.6 6.4 14.6 2.9 6.3 14.6 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein AIRC PF00731.20 EEQ40565.1 - 2.5e-63 212.1 3.8 1.2e-62 209.9 2.2 2.2 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.22 EEQ40565.1 - 1.1e-58 197.6 0.0 1.7e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EEQ40565.1 - 1e-17 63.5 0.1 2.1e-17 62.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 EEQ40565.1 - 9e-07 28.6 0.0 1.5e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 EEQ40565.1 - 4.6e-05 22.9 0.0 9e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.13 EEQ40565.1 - 0.0095 15.5 0.0 0.042 13.4 0.0 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus AlaDh_PNT_C PF01262.21 EEQ40565.1 - 0.014 14.7 1.5 0.018 14.3 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NPV_P10 PF05531.12 EEQ40565.1 - 0.087 13.3 1.2 0.2 12.1 1.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein NAD_binding_10 PF13460.6 EEQ40565.1 - 0.12 12.3 0.6 0.32 10.9 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H-binding TEA PF01285.18 EEQ40566.1 - 5.5e-24 84.0 0.0 1.1e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 TEA/ATTS domain zf-HC5HC2H_2 PF13832.6 EEQ40567.1 - 5.5e-30 103.8 6.4 5.5e-30 103.8 6.4 2.5 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EEQ40567.1 - 1.3e-27 95.9 5.0 1.3e-27 95.9 5.0 3.6 3 1 2 5 5 5 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EEQ40567.1 - 6.3e-14 51.3 2.1 6.3e-14 51.3 2.1 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EEQ40567.1 - 6e-10 38.9 9.8 6e-10 38.9 9.8 3.0 3 0 0 3 3 3 2 PHD-finger EPL1 PF10513.9 EEQ40567.1 - 6.8e-10 39.5 0.0 1.3e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Enhancer of polycomb-like RNAse_A_bac PF18431.1 EEQ40567.1 - 0.015 16.3 0.6 0.038 15.0 0.6 1.7 1 0 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain Prok-RING_1 PF14446.6 EEQ40567.1 - 0.22 11.5 16.9 0.026 14.4 5.4 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 EEQ40567.1 - 7.3 7.0 24.9 0.57 10.5 8.6 3.1 2 1 0 2 2 2 0 RING-like domain AMPKBI PF04739.15 EEQ40568.1 - 2.2e-30 104.7 2.0 7.7e-30 103.0 2.0 2.0 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 EEQ40568.1 - 7.2e-18 64.6 0.2 2e-17 63.1 0.1 1.9 2 0 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase Voldacs PF03517.13 EEQ40568.1 - 0.92 9.6 5.9 0.27 11.3 1.5 2.1 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling BAR PF03114.18 EEQ40569.1 - 3.6e-42 144.7 8.0 5e-42 144.2 8.0 1.2 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 EEQ40569.1 - 1e-05 25.2 5.8 2.4e-05 24.0 5.8 1.5 1 1 0 1 1 1 1 Arfaptin-like domain NPV_P10 PF05531.12 EEQ40569.1 - 0.33 11.5 2.9 33 5.0 0.0 3.4 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2203 PF09969.9 EEQ40569.1 - 0.75 10.5 8.1 18 6.0 1.3 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Exonuc_VII_L PF02601.15 EEQ40569.1 - 3.8 7.0 6.2 7.2 6.1 6.2 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit CLZ PF16526.5 EEQ40569.1 - 5.4 7.4 12.3 7.7 7.0 0.1 3.9 4 1 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UCH_1 PF13423.6 EEQ40570.1 - 8e-11 42.1 0.0 0.00071 19.3 0.0 3.4 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase BCIP PF13862.6 EEQ40571.1 - 3e-67 226.4 7.0 3.7e-67 226.1 7.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein XRCC4 PF06632.12 EEQ40572.1 - 0.045 12.6 3.2 0.031 13.1 1.4 1.6 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 PCI PF01399.27 EEQ40573.1 - 1e-08 35.6 0.5 1e-08 35.6 0.5 2.7 3 0 0 3 3 3 1 PCI domain DUF3499 PF12005.8 EEQ40573.1 - 0.12 13.0 1.9 0.37 11.4 1.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) Tox-ODYAM1 PF15642.6 EEQ40574.1 - 1.4 7.9 5.2 1.7 7.5 5.2 1.0 1 0 0 1 1 1 0 Toxin in Odyssella and Amoebophilus HAUS6_N PF14661.6 EEQ40574.1 - 1.4 8.4 8.4 2.1 7.9 8.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus UPF0242 PF06785.11 EEQ40574.1 - 3 7.9 14.7 3.5 7.7 14.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PfkB PF00294.24 EEQ40575.1 - 1.1e-55 189.1 1.9 1.6e-55 188.6 1.9 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EEQ40575.1 - 0.00011 21.6 0.6 0.00026 20.5 0.6 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase ELO PF01151.18 EEQ40576.1 - 4.8e-58 196.6 24.8 6e-58 196.3 24.8 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RibD_C PF01872.17 EEQ40577.1 - 1e-37 130.0 0.0 1.2e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain RNA_pol_Rpb5_C PF01191.19 EEQ40578.1 - 7.3e-32 109.1 1.4 8.4e-32 108.9 0.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain DUF3337 PF11816.8 EEQ40578.1 - 8e-24 84.4 0.1 1.7e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) RNA_pol_Rpb5_N PF03871.14 EEQ40578.1 - 3e-15 56.6 0.0 7.3e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain SH3_2 PF07653.17 EEQ40578.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain DUF3337 PF11816.8 EEQ40579.1 - 1.5e-44 151.9 0.3 3.5e-44 150.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EEQ40579.1 - 2.8e-14 53.3 11.0 2e-05 25.3 0.0 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat CENP-S PF15630.6 EEQ40580.1 - 1.6e-29 102.1 0.1 1.9e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEQ40580.1 - 2.1e-08 34.2 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Chordopox_G2 PF05796.12 EEQ40580.1 - 0.0028 17.1 0.1 0.003 17.0 0.1 1.0 1 0 0 1 1 1 1 Chordopoxvirus protein G2 Bromo_TP PF07524.13 EEQ40580.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 Bromodomain associated Amelotin PF15757.5 EEQ40580.1 - 0.2 11.2 0.0 0.25 10.9 0.0 1.1 1 0 0 1 1 1 0 Amelotin AAA_22 PF13401.6 EEQ40581.1 - 1e-10 42.0 0.0 2.9e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EEQ40581.1 - 2.3e-08 34.5 0.0 9.7e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EEQ40581.1 - 3.5e-08 34.0 0.0 1.6e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EEQ40581.1 - 7.2e-05 22.0 0.1 0.00025 20.2 0.0 2.0 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_lid_10 PF17872.1 EEQ40581.1 - 0.00018 21.5 0.1 0.0004 20.4 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain TniB PF05621.11 EEQ40581.1 - 0.00073 19.0 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein Cdc6_C PF09079.11 EEQ40581.1 - 0.012 15.5 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain AAA_19 PF13245.6 EEQ40581.1 - 0.019 15.3 0.1 0.063 13.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EEQ40581.1 - 0.048 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Methyltransf_34 PF11312.8 EEQ40581.1 - 0.056 12.7 0.1 0.09 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase TIP49 PF06068.13 EEQ40581.1 - 0.094 11.9 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain Myb_DNA-binding PF00249.31 EEQ40582.1 - 9.8e-14 51.3 0.0 2.7e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ40582.1 - 0.0045 17.2 3.8 0.1 12.9 0.1 3.7 4 0 0 4 4 4 1 Myb-like DNA-binding domain Ribosomal_S9 PF00380.19 EEQ40583.1 - 1.6e-41 141.6 0.3 3e-41 140.8 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Fer4_14 PF13394.6 EEQ40583.1 - 0.2 11.8 0.0 1.3 9.1 0.0 2.2 2 1 1 3 3 3 0 4Fe-4S single cluster domain tRNA_SAD PF07973.14 EEQ40584.1 - 8.1e-08 32.2 0.2 1.7e-07 31.2 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EEQ40584.1 - 1.6e-07 30.2 0.2 3.2e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) DUF4446 PF14584.6 EEQ40584.1 - 0.048 13.7 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Vma12 PF11712.8 EEQ40585.1 - 4.6e-37 127.2 0.1 6e-37 126.8 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF981 PF06168.11 EEQ40585.1 - 0.0043 17.0 0.0 0.0054 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF981) DnaG_DnaB_bind PF08278.11 EEQ40585.1 - 0.091 13.4 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Alpha_TIF PF02232.15 EEQ40585.1 - 0.1 11.7 0.1 0.22 10.6 0.0 1.5 2 0 0 2 2 2 0 Alpha trans-inducing protein (Alpha-TIF) TMEMspv1-c74-12 PF11044.8 EEQ40585.1 - 3.3 7.8 10.5 0.29 11.1 1.2 2.6 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Prenyltransf PF01255.19 EEQ40586.1 - 5.1e-08 32.7 0.1 6.2e-08 32.4 0.1 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase CBS PF00571.28 EEQ40587.1 - 1.5e-34 118.2 6.6 1e-09 38.7 0.0 5.4 5 1 0 5 5 5 4 CBS domain PB1 PF00564.24 EEQ40587.1 - 1.1e-11 44.5 0.2 3.4e-11 42.9 0.2 1.9 1 0 0 1 1 1 1 PB1 domain Flagellin_IN PF07196.13 EEQ40587.1 - 0.0041 17.3 0.1 0.046 13.9 0.0 2.6 2 0 0 2 2 2 1 Flagellin hook IN motif Ribosomal_L50 PF10501.9 EEQ40588.1 - 2.5e-29 101.6 0.0 4.4e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal subunit 39S Rhomboid PF01694.22 EEQ40589.1 - 4.9e-31 107.8 13.1 4.9e-31 107.8 13.1 2.0 3 0 0 3 3 3 1 Rhomboid family DUF4668 PF15701.5 EEQ40589.1 - 0.0022 17.8 0.3 0.0059 16.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4668) Brix PF04427.18 EEQ40590.1 - 3.4e-41 141.5 0.4 4.4e-41 141.1 0.4 1.1 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 EEQ40590.1 - 0.052 12.1 0.2 0.066 11.8 0.2 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin Xpo1 PF08389.12 EEQ40591.1 - 0.21 11.6 3.0 63 3.6 0.0 4.6 5 0 0 5 5 5 0 Exportin 1-like protein RasGAP PF00616.19 EEQ40593.1 - 2e-14 53.8 0.4 7.5e-14 51.9 0.2 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase VATC PF18716.1 EEQ40593.1 - 0.96 9.4 4.7 23 4.9 1.7 3.0 2 0 0 2 2 2 0 Vms1-associating treble clef domain RNase_T PF00929.24 EEQ40595.1 - 2.1e-14 54.4 0.0 3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EEQ40595.1 - 0.013 15.3 0.0 0.058 13.1 0.0 2.1 1 1 0 1 1 1 0 3'-5' exonuclease CRIM PF16978.5 EEQ40596.1 - 2.1e-27 96.0 0.0 1.4e-26 93.3 0.0 2.5 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EEQ40596.1 - 1.3e-13 51.1 10.7 3.2e-13 49.9 7.1 3.0 2 1 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Pkinase PF00069.25 EEQ40597.1 - 1.7e-65 221.0 0.1 2.8e-65 220.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40597.1 - 6e-32 110.9 0.0 1e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ40597.1 - 1.2e-07 31.3 0.0 4.3e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EEQ40597.1 - 0.00036 20.0 0.1 0.00067 19.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEQ40597.1 - 0.0017 18.0 0.5 0.45 10.1 0.0 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EEQ40597.1 - 0.0088 15.7 0.1 0.021 14.4 0.1 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EEQ40597.1 - 0.015 15.2 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EEQ40597.1 - 0.033 13.1 4.6 0.022 13.7 1.2 2.3 3 0 0 3 3 3 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EEQ40597.1 - 0.036 12.9 0.0 0.036 12.9 0.0 3.5 4 0 0 4 4 4 0 Fungal protein kinase Seadorna_VP7 PF07387.11 EEQ40597.1 - 0.056 12.5 0.1 0.12 11.5 0.0 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 PIP49_C PF12260.8 EEQ40597.1 - 0.069 12.8 1.8 0.12 12.0 0.0 2.2 3 0 0 3 3 3 0 Protein-kinase domain of FAM69 tRNA-synt_1b PF00579.25 EEQ40598.1 - 8.3e-18 64.7 0.0 6.8e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Inos-1-P_synth PF01658.17 EEQ40598.1 - 0.1 12.8 0.1 0.45 10.8 0.1 2.0 2 0 0 2 2 2 0 Myo-inositol-1-phosphate synthase POC3_POC4 PF10448.9 EEQ40599.1 - 3.6e-24 85.4 0.2 4e-24 85.3 0.2 1.0 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 DHBP_synthase PF00926.19 EEQ40600.1 - 2.2e-86 288.3 0.1 2.4e-86 288.2 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase RNB PF00773.19 EEQ40601.1 - 5e-100 335.0 0.0 9.3e-100 334.1 0.0 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EEQ40601.1 - 4.2e-44 149.8 0.0 1.3e-43 148.3 0.0 1.9 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EEQ40601.1 - 3.1e-28 97.6 2.0 3.1e-28 97.6 2.0 2.2 2 0 0 2 2 2 1 S1 domain OB_Dis3 PF17849.1 EEQ40601.1 - 7.1e-19 67.6 0.0 1.8e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EEQ40601.1 - 5.9e-17 62.2 1.6 1.5e-16 60.8 1.6 1.8 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EEQ40601.1 - 2.7e-08 33.9 0.0 5.9e-05 23.2 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain OB_RNB PF08206.11 EEQ40601.1 - 0.055 13.2 0.1 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease B OB domain PIN_12 PF16289.5 EEQ40601.1 - 0.89 10.0 6.7 0.1 13.1 1.6 2.1 2 0 0 2 2 2 0 PIN domain Frag1 PF10277.9 EEQ40602.1 - 1.5e-58 198.0 25.3 1.7e-58 197.7 25.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Caps_synth_CapC PF14102.6 EEQ40602.1 - 0.29 11.5 6.7 0.34 11.3 5.1 2.0 1 1 0 1 1 1 0 Capsule biosynthesis CapC GWT1 PF06423.12 EEQ40602.1 - 9 6.4 14.4 0.27 11.4 7.4 2.1 2 1 0 2 2 2 0 GWT1 HPP PF04982.13 EEQ40603.1 - 1.1e-38 132.1 6.5 1.1e-37 128.9 4.9 2.1 2 0 0 2 2 2 2 HPP family SSF PF00474.17 EEQ40604.1 - 3.5e-05 22.9 17.5 8.9e-05 21.5 17.5 1.8 1 1 0 1 1 1 1 Sodium:solute symporter family OFeT_1 PF16955.5 EEQ40604.1 - 0.019 14.7 0.5 0.019 14.7 0.5 2.5 2 1 1 3 3 3 0 Ferrous iron uptake permease, iron-lead transporter NUP PF06516.11 EEQ40605.1 - 2e-127 424.7 0.1 2.4e-127 424.5 0.1 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) MF_alpha_N PF05436.11 EEQ40605.1 - 0.11 12.5 0.4 0.23 11.4 0.4 1.6 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Sec20 PF03908.13 EEQ40607.1 - 2.2e-24 85.2 2.8 2.2e-24 85.2 2.8 2.5 2 0 0 2 2 2 1 Sec20 LMBR1 PF04791.16 EEQ40607.1 - 1.4 7.8 6.3 2.1 7.2 6.3 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein GFO_IDH_MocA PF01408.22 EEQ40608.1 - 1.5e-20 74.2 0.1 3e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEQ40608.1 - 1.9e-06 27.9 0.0 3.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain RRM_1 PF00076.22 EEQ40609.1 - 5.1e-09 35.8 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PT PF04886.12 EEQ40609.1 - 0.01 15.4 8.9 0.01 15.4 8.9 3.0 2 0 0 2 2 2 1 PT repeat RRM_5 PF13893.6 EEQ40609.1 - 0.022 14.3 0.0 0.088 12.4 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC37_C PF08564.10 EEQ40610.1 - 2.7e-22 78.8 2.0 3.2e-22 78.5 1.1 1.5 1 1 0 1 1 1 1 Cdc37 C terminal domain CDC37_M PF08565.11 EEQ40610.1 - 0.011 15.7 0.3 0.037 14.0 0.2 1.9 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain Glyco_transf_29 PF00777.18 EEQ40610.1 - 0.054 12.9 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) Lipl32 PF12103.8 EEQ40610.1 - 0.17 11.5 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order CDC37_M PF08565.11 EEQ40611.1 - 5.6e-29 100.5 1.0 1.3e-28 99.3 1.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_N PF03234.14 EEQ40611.1 - 3.5e-07 31.2 6.1 4.4e-07 30.9 0.3 2.7 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding Endostatin PF06482.11 EEQ40611.1 - 0.15 11.5 0.3 0.2 11.1 0.3 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin EutQ PF06249.12 EEQ40612.1 - 4.2e-07 29.8 0.0 4.9e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 EEQ40612.1 - 2.9e-06 26.9 0.1 4.2e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 EEQ40612.1 - 0.0025 17.5 0.1 0.0037 16.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Pirin PF02678.16 EEQ40612.1 - 0.088 12.8 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Pirin VPS9 PF02204.18 EEQ40613.1 - 2.1e-29 101.8 0.4 4.7e-29 100.7 0.4 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EEQ40613.1 - 4.5e-12 46.1 0.1 2.9e-11 43.5 0.1 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 EEQ40613.1 - 0.0027 17.4 0.1 0.0056 16.4 0.1 1.5 1 0 0 1 1 1 1 CUE domain HEAT_2 PF13646.6 EEQ40614.1 - 0.011 16.1 0.0 0.3 11.5 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats ATP_bind_3 PF01171.20 EEQ40615.1 - 4.3e-44 150.5 0.0 6.6e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 EEQ40615.1 - 0.001 18.8 0.0 0.065 12.9 0.0 2.4 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.13 EEQ40615.1 - 0.015 14.8 0.0 0.077 12.5 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EEQ40615.1 - 0.13 11.0 0.0 0.29 9.9 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase tRNA-synt_1 PF00133.22 EEQ40616.1 - 1.3e-231 770.1 0.2 2.1e-231 769.4 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EEQ40616.1 - 1.1e-23 83.9 0.0 2.8e-23 82.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EEQ40616.1 - 8.5e-15 54.4 0.3 2.8e-05 23.1 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EEQ40616.1 - 0.0046 16.4 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain PHtD_u1 PF16645.5 EEQ40616.1 - 1.1 9.8 2.7 4.7 7.7 0.2 2.6 2 0 0 2 2 2 0 Unstructured region on Pneumococcal histidine triad protein WD40 PF00400.32 EEQ40617.1 - 2.1e-14 53.7 17.3 1e-06 29.3 0.0 9.9 10 0 0 10 10 10 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ40617.1 - 3e-08 33.8 2.5 0.45 10.9 0.0 7.3 4 2 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EEQ40617.1 - 0.0062 15.9 3.4 0.77 9.0 0.0 3.8 3 1 1 4 4 4 2 CPSF A subunit region BBS2_Mid PF14783.6 EEQ40617.1 - 0.0093 16.0 1.1 34 4.5 0.0 5.2 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Epimerase PF01370.21 EEQ40618.1 - 3.5e-18 66.0 0.0 4.8e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ40618.1 - 5.9e-14 51.7 0.0 8.1e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EEQ40618.1 - 5.4e-07 29.0 0.0 0.00085 18.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EEQ40618.1 - 1.5e-06 28.3 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EEQ40618.1 - 1.9e-05 24.2 0.1 3.2e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EEQ40618.1 - 4.5e-05 23.0 0.1 8.6e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EEQ40618.1 - 0.0004 20.3 0.0 0.00072 19.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EEQ40618.1 - 0.00049 19.3 0.1 0.0007 18.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 EEQ40618.1 - 0.0026 17.3 0.1 0.0052 16.4 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_hydro81C PF17652.1 EEQ40619.1 - 4e-132 440.7 9.1 5.6e-132 440.2 9.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EEQ40619.1 - 3.7e-80 269.5 5.1 8.2e-80 268.4 5.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain FTR1 PF03239.14 EEQ40620.1 - 1.6e-96 323.1 7.2 2e-96 322.8 7.2 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family MgtE PF01769.16 EEQ40620.1 - 0.37 11.2 15.0 0.85 10.0 1.5 3.1 4 0 0 4 4 4 0 Divalent cation transporter FAA_hydrolase PF01557.18 EEQ40621.1 - 1.2e-54 185.3 0.0 1.8e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family dCMP_cyt_deam_1 PF00383.23 EEQ40622.1 - 9.7e-27 92.8 1.7 1.5e-26 92.2 1.7 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EEQ40622.1 - 4.6e-13 49.1 0.3 8.4e-13 48.2 0.3 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 EEQ40622.1 - 0.0031 18.1 0.1 0.048 14.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EEQ40622.1 - 0.065 13.5 0.1 0.16 12.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain NPC1_N PF16414.5 EEQ40623.1 - 9.8e-80 267.6 10.5 1.6e-79 267.0 10.5 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EEQ40623.1 - 1.8e-67 228.1 23.4 5.3e-66 223.3 20.4 3.2 2 1 0 2 2 2 1 Patched family Sterol-sensing PF12349.8 EEQ40623.1 - 1.1e-48 164.9 7.1 1.1e-48 164.9 7.1 2.9 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation DUF3484 PF11983.8 EEQ40624.1 - 0.075 14.1 1.8 0.075 14.1 1.8 5.8 2 1 1 3 3 3 0 Membrane-attachment and polymerisation-promoting switch PRCH PF03967.13 EEQ40624.1 - 0.8 9.9 0.0 0.8 9.9 0.0 3.0 2 1 0 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region Dynactin_p62 PF05502.13 EEQ40626.1 - 1.4e-10 40.6 26.3 8.4e-06 24.8 20.5 2.3 1 1 1 2 2 2 2 Dynactin p62 family DNA_RNApol_7kD PF03604.13 EEQ40627.1 - 3.1e-16 58.7 3.2 4.2e-16 58.3 3.2 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 EEQ40627.1 - 0.00025 21.0 0.2 0.00025 21.0 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbon_6 PF10005.9 EEQ40627.1 - 0.0016 19.1 0.5 0.002 18.7 0.5 1.2 1 0 0 1 1 1 1 zinc-ribbon domain Zn-ribbon_8 PF09723.10 EEQ40627.1 - 0.0025 17.9 2.4 0.0055 16.8 2.4 1.6 1 1 0 1 1 1 1 Zinc ribbon domain DZR PF12773.7 EEQ40627.1 - 0.0027 17.7 1.4 0.006 16.6 1.1 1.7 1 1 1 2 2 2 2 Double zinc ribbon C1_1 PF00130.22 EEQ40627.1 - 0.0032 17.3 0.9 0.0042 16.9 0.9 1.2 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EEQ40627.1 - 0.004 17.0 0.3 0.0055 16.6 0.3 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 EEQ40627.1 - 0.0042 16.7 0.7 1.1 8.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger A2L_zn_ribbon PF08792.10 EEQ40627.1 - 0.0061 16.3 1.1 3.1 7.6 0.0 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain FYDLN_acid PF09538.10 EEQ40627.1 - 0.0071 17.0 0.2 0.0078 16.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (FYDLN_acid) zinc_ribbon_5 PF13719.6 EEQ40627.1 - 0.0082 15.9 1.7 0.17 11.7 0.1 2.2 2 0 0 2 2 2 1 zinc-ribbon domain zf-C3HC PF07967.13 EEQ40627.1 - 0.011 15.8 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 0 C3HC zinc finger-like TackOD1 PF18551.1 EEQ40627.1 - 0.014 15.1 0.8 0.015 15.0 0.8 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 TFIIS_C PF01096.18 EEQ40627.1 - 0.015 15.1 1.2 2.2 8.2 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) OrfB_Zn_ribbon PF07282.11 EEQ40627.1 - 0.016 15.1 0.7 2.9 7.9 0.1 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF1451 PF07295.11 EEQ40627.1 - 0.024 14.7 0.4 0.027 14.5 0.4 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain zf-HYPF PF07503.12 EEQ40627.1 - 0.027 14.2 0.5 3.3 7.6 0.1 2.2 2 0 0 2 2 2 0 HypF finger zf-C2H2_6 PF13912.6 EEQ40627.1 - 0.034 14.1 4.0 0.16 12.0 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Rubredoxin_2 PF18073.1 EEQ40627.1 - 0.036 13.8 5.1 1.9 8.3 0.7 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-trcl PF13451.6 EEQ40627.1 - 0.041 13.8 2.3 3.4 7.7 0.1 2.2 1 1 1 2 2 2 0 Probable zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EEQ40627.1 - 0.044 13.7 0.3 0.057 13.4 0.3 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon DUF951 PF06107.11 EEQ40627.1 - 0.053 13.4 1.0 1.1 9.2 0.3 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) zinc_ribbon_13 PF09855.9 EEQ40627.1 - 0.054 13.7 0.3 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-ribbon_3 PF13248.6 EEQ40627.1 - 0.062 12.7 3.6 0.25 10.8 3.6 1.9 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 EEQ40627.1 - 0.066 13.1 4.5 3.4 7.7 4.5 2.2 1 1 1 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EEQ40627.1 - 0.071 12.8 1.9 7.6 6.4 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 EEQ40627.1 - 0.077 13.5 4.8 0.3 11.6 0.8 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.9 EEQ40627.1 - 0.079 13.1 2.4 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RNA_POL_M_15KD PF02150.16 EEQ40627.1 - 0.099 12.5 1.3 0.57 10.1 0.1 2.1 1 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit ZZ PF00569.17 EEQ40627.1 - 0.16 11.8 2.5 8.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type CpXC PF14353.6 EEQ40627.1 - 0.19 11.8 1.1 14 5.8 0.1 2.1 1 1 1 2 2 2 0 CpXC protein zf-Mss51 PF13824.6 EEQ40627.1 - 0.21 11.7 2.4 1.8 8.7 0.2 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2_3 PF13878.6 EEQ40627.1 - 0.42 10.5 4.5 3 7.8 0.4 2.2 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_11 PF16622.5 EEQ40627.1 - 0.66 9.8 4.7 7.3 6.4 0.4 2.4 1 1 1 2 2 2 0 zinc-finger C2H2-type Zn_Tnp_IS1595 PF12760.7 EEQ40627.1 - 0.79 9.7 5.5 1.4 8.9 0.8 2.1 1 1 0 2 2 2 0 Transposase zinc-ribbon domain DUF983 PF06170.12 EEQ40627.1 - 2 8.9 3.7 3.6 8.0 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF983) Aa_trans PF01490.18 EEQ40629.1 - 1.6e-97 326.8 32.3 1.8e-97 326.6 32.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Malate_synthase PF01274.22 EEQ40629.1 - 0.025 12.9 0.0 0.035 12.4 0.0 1.1 1 0 0 1 1 1 0 Malate synthase TRAM_LAG1_CLN8 PF03798.16 EEQ40630.1 - 1.3e-43 149.1 25.5 1.3e-43 149.1 25.5 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EEQ40630.1 - 1.3e-14 53.6 4.5 1.9e-14 53.1 0.1 2.4 2 0 0 2 2 2 1 TRAM1-like protein Cyclin_N PF00134.23 EEQ40631.1 - 6.8e-15 54.9 0.7 1.6e-14 53.7 0.7 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EEQ40631.1 - 0.048 14.0 0.3 0.11 12.9 0.3 1.8 1 1 0 1 1 1 0 Cyclin C-terminal domain Pro_isomerase PF00160.21 EEQ40632.1 - 7e-30 104.4 0.3 7.7e-30 104.2 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DFP PF04127.15 EEQ40633.1 - 1.9e-18 67.0 0.0 3.4e-10 40.1 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Bac_surface_Ag PF01103.23 EEQ40634.1 - 1.1e-34 120.4 0.3 1.5e-34 119.9 0.3 1.2 1 0 0 1 1 1 1 Surface antigen zf-C2H2 PF00096.26 EEQ40635.1 - 1.3e-14 53.7 11.8 1.2e-06 28.7 1.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ40635.1 - 5.9e-14 51.8 9.3 1.2e-07 31.8 0.3 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ40635.1 - 4.2e-10 39.6 9.4 0.00039 21.0 0.9 4.3 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ40635.1 - 3e-07 30.5 2.4 0.0029 17.9 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ40635.1 - 4.7e-07 30.0 6.4 5.9e-05 23.3 0.2 4.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ40635.1 - 3.2e-05 23.8 8.4 0.0062 16.5 0.2 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf_UBZ PF18439.1 EEQ40635.1 - 0.013 15.0 1.1 0.47 10.1 0.3 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 EEQ40635.1 - 0.1 12.4 5.1 0.94 9.3 0.1 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type FPP PF05911.11 EEQ40635.1 - 0.12 10.6 1.6 0.18 10.0 1.6 1.2 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Zn-ribbon_8 PF09723.10 EEQ40635.1 - 0.12 12.5 1.1 0.29 11.3 1.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 EEQ40635.1 - 0.14 12.7 2.2 0.13 12.7 0.6 1.8 2 0 0 2 2 1 0 Recombinase zinc beta ribbon domain zf-Di19 PF05605.12 EEQ40635.1 - 0.16 12.3 1.1 0.74 10.1 1.5 2.0 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding FYVE PF01363.21 EEQ40635.1 - 0.42 10.8 4.4 0.92 9.7 4.4 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-C2HC_2 PF13913.6 EEQ40635.1 - 1.4 9.0 8.4 0.23 11.4 0.2 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Met_10 PF02475.16 EEQ40636.1 - 1.6e-08 34.5 0.0 2.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 EEQ40636.1 - 0.041 13.4 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_9 PF08003.11 EEQ40636.1 - 0.082 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RRM_1 PF00076.22 EEQ40637.1 - 1.3e-55 185.1 1.8 3.6e-21 74.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ40637.1 - 2.1e-12 46.7 0.0 1.8e-05 24.5 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EEQ40637.1 - 1.1e-06 28.3 0.0 0.026 14.1 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ40637.1 - 1.1e-06 28.6 0.1 0.021 14.9 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EEQ40637.1 - 0.00028 20.8 0.2 0.1 12.6 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EEQ40637.1 - 0.0017 18.6 0.5 3.9 7.7 0.1 3.3 2 1 0 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_9 PF18444.1 EEQ40637.1 - 0.034 14.0 0.3 0.38 10.6 0.1 2.3 2 0 0 2 2 2 0 RNA recognition motif Trep_dent_lipo PF09710.10 EEQ40637.1 - 0.055 12.4 0.3 0.078 11.9 0.3 1.3 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) UCH PF00443.29 EEQ40638.1 - 7.5e-43 146.9 0.3 2.1e-26 93.0 0.2 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ40638.1 - 1.3e-06 28.2 1.2 1.3e-06 28.2 1.2 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SMN PF06003.12 EEQ40638.1 - 0.023 14.0 4.2 0.045 13.0 4.2 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Zip PF02535.22 EEQ40638.1 - 1.3 8.1 3.6 2.6 7.2 3.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2431 PF10354.9 EEQ40639.1 - 3.7e-36 124.9 0.0 4.4e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CLTH PF10607.9 EEQ40640.1 - 7.3e-27 94.1 2.9 1.2e-26 93.4 0.3 2.4 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain NBP1 PF08537.10 EEQ40640.1 - 0.16 11.3 4.1 0.28 10.6 4.1 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 LisH PF08513.11 EEQ40640.1 - 0.19 11.7 0.3 0.46 10.5 0.3 1.7 1 0 0 1 1 1 0 LisH DUF1542 PF07564.11 EEQ40640.1 - 0.46 10.6 6.7 0.46 10.6 5.2 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF1664 PF07889.12 EEQ40640.1 - 0.47 10.5 2.5 1 9.4 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) GDA1_CD39 PF01150.17 EEQ40641.1 - 1.4e-74 251.2 0.0 7.2e-68 229.2 0.0 2.9 2 1 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ras PF00071.22 EEQ40642.1 - 4.8e-49 166.1 0.9 5.5e-49 165.9 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ40642.1 - 1e-16 61.2 0.0 1.6e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ40642.1 - 1.2e-06 28.1 0.1 1.4e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ40642.1 - 1e-05 25.2 0.1 3.6e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEQ40642.1 - 5e-05 23.4 0.0 8.4e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EEQ40642.1 - 5.4e-05 22.7 0.1 7.1e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 EEQ40642.1 - 0.014 15.4 0.5 0.065 13.3 0.0 2.0 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EEQ40642.1 - 0.018 14.9 0.3 0.21 11.5 0.0 2.1 1 1 1 2 2 2 0 RsgA GTPase Mem_trans PF03547.18 EEQ40643.1 - 4.9e-65 219.4 12.9 6.6e-65 219.0 12.9 1.1 1 0 0 1 1 1 1 Membrane transport protein ASF1_hist_chap PF04729.13 EEQ40645.1 - 4.7e-71 237.7 0.0 6.9e-71 237.2 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Mpp10 PF04006.12 EEQ40645.1 - 0.033 12.6 27.7 0.042 12.3 27.7 1.0 1 0 0 1 1 1 0 Mpp10 protein Na_trans_assoc PF06512.13 EEQ40645.1 - 0.037 14.3 14.1 0.044 14.1 14.1 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated TFIIF_alpha PF05793.12 EEQ40645.1 - 0.1 11.1 26.6 0.12 10.9 26.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 EEQ40645.1 - 0.25 9.5 30.8 0.29 9.3 30.8 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EEQ40645.1 - 1.6 8.1 31.3 1.9 7.8 31.3 1.1 1 0 0 1 1 1 0 SDA1 VIR_N PF15912.5 EEQ40645.1 - 1.9 8.0 16.2 2.4 7.7 16.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal CDC45 PF02724.14 EEQ40645.1 - 3 6.0 24.9 4 5.6 24.9 1.1 1 0 0 1 1 1 0 CDC45-like protein MDM1 PF15501.6 EEQ40645.1 - 3.5 6.7 15.2 4.3 6.4 15.2 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 SAPS PF04499.15 EEQ40645.1 - 3.5 6.3 10.6 4.3 6.0 10.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 EEQ40645.1 - 3.6 6.2 10.0 4.8 5.8 10.0 1.1 1 0 0 1 1 1 0 Presenilin Drc1-Sld2 PF11719.8 EEQ40645.1 - 4.1 6.9 18.4 4.8 6.6 18.4 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein Merozoite_SPAM PF07133.11 EEQ40645.1 - 7.9 6.4 46.7 13 5.7 46.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) eIF-3c_N PF05470.12 EEQ40645.1 - 8.3 4.6 16.2 9.9 4.3 16.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DUF2722 PF10846.8 EEQ40645.1 - 8.8 5.1 15.4 10 4.9 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DEK_C PF08766.11 EEQ40646.1 - 0.0029 17.5 0.4 0.37 10.8 0.1 2.5 2 0 0 2 2 2 2 DEK C terminal domain Ino80_Iec3 PF14612.6 EEQ40646.1 - 0.061 14.0 2.6 0.089 13.4 1.5 1.5 1 1 1 2 2 2 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling Bac_rhamnosid6H PF17389.2 EEQ40646.1 - 0.34 10.1 1.6 0.48 9.6 1.6 1.1 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain RICTOR_N PF14664.6 EEQ40647.1 - 1.7e-108 363.0 5.8 3.4e-108 362.0 5.8 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_V PF14668.6 EEQ40647.1 - 3.5e-25 88.0 1.2 4.8e-23 81.2 0.1 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 RICTOR_M PF14666.6 EEQ40647.1 - 1.1e-23 83.0 0.2 1.1e-23 83.0 0.2 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EEQ40647.1 - 2.2e-10 40.9 5.1 6.1e-10 39.5 0.0 4.2 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.23 EEQ40647.1 - 0.046 13.8 5.5 8.6 6.6 0.0 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CTNNBL PF08216.11 EEQ40647.1 - 0.067 13.4 0.7 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 Catenin-beta-like, Arm-motif containing nuclear sCache_2 PF17200.4 EEQ40647.1 - 0.18 11.7 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 Single Cache domain 2 Arm_3 PF16186.5 EEQ40647.1 - 0.64 9.6 2.8 52 3.5 0.0 3.5 3 0 0 3 3 3 0 Atypical Arm repeat FAD-SLDH PF12318.8 EEQ40648.1 - 0.21 11.7 0.6 0.39 10.8 0.6 1.4 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Brix PF04427.18 EEQ40649.1 - 9.2e-29 100.9 0.7 1.2e-28 100.5 0.7 1.2 1 0 0 1 1 1 1 Brix domain TrkH PF02386.16 EEQ40650.1 - 5e-167 556.3 6.6 5e-167 556.3 6.6 2.1 2 0 0 2 2 2 2 Cation transport protein DUF99 PF01949.16 EEQ40650.1 - 0.094 12.1 0.0 8.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF99 CPSase_L_D2 PF02786.17 EEQ40651.1 - 2.4e-115 383.3 1.0 9.7e-85 283.4 0.1 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EEQ40651.1 - 1.3e-46 157.5 0.0 3.1e-46 156.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EEQ40651.1 - 4.9e-45 153.7 0.0 1.2e-44 152.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EEQ40651.1 - 3.3e-39 134.0 0.0 7.4e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 EEQ40651.1 - 4e-20 71.8 0.0 3.2e-19 68.9 0.0 2.7 3 0 0 3 3 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EEQ40651.1 - 3.4e-18 65.9 2.0 3.2e-10 39.9 0.2 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EEQ40651.1 - 1e-14 54.5 0.3 1.5e-07 31.2 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EEQ40651.1 - 2.5e-10 40.2 0.0 5.6e-05 22.9 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EEQ40651.1 - 1.1e-06 28.8 0.6 0.011 15.8 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EEQ40651.1 - 1.1e-06 28.5 0.8 0.00013 21.9 0.1 2.8 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 EEQ40651.1 - 0.00015 21.6 0.6 0.022 14.5 0.0 4.0 5 0 0 5 5 5 1 DJ-1/PfpI family TrkA_N PF02254.18 EEQ40651.1 - 0.039 14.2 1.3 0.36 11.1 0.0 3.1 4 0 0 4 4 4 0 TrkA-N domain OTCace_N PF02729.21 EEQ40652.1 - 1.2e-47 161.7 0.0 1.9e-47 161.0 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EEQ40652.1 - 3.8e-30 105.0 0.0 9.4e-30 103.8 0.0 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain zf-H2C2 PF09337.10 EEQ40653.1 - 4e-14 52.5 1.6 9e-14 51.4 1.6 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EEQ40653.1 - 9.1e-11 41.7 0.2 1.6e-10 41.0 0.2 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EEQ40653.1 - 7.6e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ40653.1 - 0.0089 16.4 0.0 0.03 14.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EEQ40653.1 - 0.046 14.4 0.0 0.082 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PMEI PF04043.15 EEQ40653.1 - 0.051 13.9 0.1 0.082 13.2 0.1 1.2 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor FR47 PF08445.10 EEQ40653.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 EEQ40654.1 - 2.5e-06 27.7 0.3 3.8e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EEQ40654.1 - 0.00022 21.9 0.0 0.00029 21.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EEQ40654.1 - 0.0063 16.7 0.1 0.0084 16.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EEQ40654.1 - 0.022 14.7 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.7 EEQ40654.1 - 0.05 14.0 0.1 0.092 13.2 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Sds3 PF08598.11 EEQ40655.1 - 7.1e-52 176.6 1.1 1.6e-51 175.4 1.1 1.5 1 1 0 1 1 1 1 Sds3-like DUF1844 PF08899.11 EEQ40655.1 - 1.5 9.2 4.5 0.43 10.9 0.8 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1844) Glyco_transf_15 PF01793.16 EEQ40656.1 - 1.7e-94 316.8 13.0 1.5e-61 208.5 3.5 2.2 2 0 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase CENP-T_C PF15511.6 EEQ40657.1 - 9.1e-10 38.6 0.1 1.1e-09 38.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 EEQ40657.1 - 1.7e-05 24.9 0.1 2.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EEQ40657.1 - 3.8e-05 23.9 0.1 6.5e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ40657.1 - 8.4e-05 22.9 0.1 9.8e-05 22.7 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEQ40657.1 - 8.8e-05 22.8 0.1 0.00012 22.4 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EEQ40657.1 - 0.0026 17.8 0.0 0.0031 17.6 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EEQ40657.1 - 0.0047 16.9 0.0 0.0056 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 EEQ40657.1 - 0.019 14.8 0.2 0.023 14.5 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TAFII28 PF04719.14 EEQ40657.1 - 0.051 13.7 0.0 0.06 13.4 0.0 1.1 1 0 0 1 1 1 0 hTAFII28-like protein conserved region TFIID_20kDa PF03847.13 EEQ40657.1 - 0.069 13.7 0.1 0.13 12.8 0.1 1.4 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A Aim19 PF10315.9 EEQ40658.1 - 1.6e-44 150.9 3.2 1.8e-44 150.7 3.2 1.0 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Y_phosphatase2 PF03162.13 EEQ40659.1 - 5.9e-55 185.3 0.0 8.3e-55 184.8 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EEQ40659.1 - 1.5e-07 31.7 0.0 2.6e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EEQ40659.1 - 0.0022 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EEQ40659.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain STE2 PF02116.15 EEQ40660.1 - 4.4e-70 236.2 23.5 5.2e-70 235.9 23.5 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Col_cuticle_N PF01484.17 EEQ40660.1 - 3.4 7.8 7.7 0.29 11.2 0.3 2.8 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Ycf66_N PF07444.11 EEQ40660.1 - 3.9 7.7 10.5 0.4 10.8 0.7 2.9 3 0 0 3 3 3 0 Ycf66 protein N-terminus AMPK1_CBM PF16561.5 EEQ40661.1 - 2.4e-30 104.6 0.2 5.7e-30 103.4 0.2 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EEQ40661.1 - 7e-28 96.7 4.0 7e-28 96.7 4.0 2.7 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain RP-C_C PF11800.8 EEQ40661.1 - 0.01 16.0 5.0 0.019 15.0 1.3 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region CBM53 PF16760.5 EEQ40661.1 - 0.031 14.9 0.3 0.15 12.6 0.0 2.3 2 1 0 2 2 2 0 Starch/carbohydrate-binding module (family 53) DUF3276 PF11680.8 EEQ40661.1 - 7.3 6.7 9.0 3.7 7.7 1.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3276) CCDC53 PF10152.9 EEQ40661.1 - 8.5 6.8 14.2 0.056 13.9 2.1 2.5 2 1 0 2 2 2 0 Subunit CCDC53 of WASH complex AA_permease PF00324.21 EEQ40662.1 - 4.5e-106 355.3 34.9 5.2e-106 355.1 34.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ40662.1 - 1.4e-22 80.2 41.0 1.9e-22 79.7 41.0 1.2 1 0 0 1 1 1 1 Amino acid permease Git3 PF11710.8 EEQ40663.1 - 9.7e-73 244.3 17.4 1.6e-72 243.5 17.4 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EEQ40663.1 - 9.1e-36 121.8 2.0 2.5e-35 120.4 2.0 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EEQ40663.1 - 1.9e-06 27.4 0.1 3.4e-06 26.6 0.1 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) TMEM189_B_dmain PF10520.9 EEQ40663.1 - 0.24 11.5 1.5 0.42 10.7 0.2 1.9 2 0 0 2 2 2 0 B domain of TMEM189, localisation domain DUF21 PF01595.20 EEQ40663.1 - 0.35 10.6 3.6 1.4 8.5 0.9 2.5 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain MFS_1 PF07690.16 EEQ40664.1 - 9.3e-39 133.3 52.1 2.4e-38 132.0 52.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ40664.1 - 2e-18 66.2 17.2 3.2e-18 65.5 17.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ40664.1 - 1.4e-11 43.9 13.5 1.4e-11 43.9 13.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter Nuf2 PF03800.14 EEQ40665.1 - 9e-43 145.7 1.9 1.1e-42 145.5 0.1 2.1 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 EEQ40665.1 - 5.7e-19 68.3 29.6 5.7e-19 68.3 29.6 3.6 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain GAS PF13851.6 EEQ40665.1 - 0.00019 20.8 52.0 0.085 12.2 12.3 3.2 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EEQ40665.1 - 0.00099 18.1 51.5 0.0012 17.8 22.1 3.1 1 1 2 3 3 3 3 Spc7 kinetochore protein Mce4_CUP1 PF11887.8 EEQ40665.1 - 0.0014 18.1 1.1 0.0014 18.1 1.1 2.1 1 1 1 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative GIT_CC PF16559.5 EEQ40665.1 - 0.0043 16.9 4.1 0.0043 16.9 4.1 4.2 3 1 2 5 5 5 1 GIT coiled-coil Rho guanine nucleotide exchange factor Ubiquitin_3 PF14836.6 EEQ40665.1 - 0.011 15.7 7.5 0.014 15.3 1.0 3.2 3 0 0 3 3 3 0 Ubiquitin-like domain DivIC PF04977.15 EEQ40665.1 - 0.019 14.7 3.4 0.019 14.7 3.4 5.6 3 1 3 6 6 6 0 Septum formation initiator GPS2_interact PF15784.5 EEQ40665.1 - 0.021 15.3 8.8 0.021 15.3 8.8 4.0 2 2 3 5 5 5 0 G-protein pathway suppressor 2-interacting domain DUF3584 PF12128.8 EEQ40665.1 - 0.056 11.0 44.4 0.049 11.2 25.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 EEQ40665.1 - 0.089 12.8 19.6 0.32 11.0 4.2 4.0 2 1 3 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Jnk-SapK_ap_N PF09744.9 EEQ40665.1 - 0.11 12.7 51.5 0.87 9.8 5.7 3.5 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 RasGAP_C PF03836.15 EEQ40665.1 - 0.5 10.5 34.9 0.44 10.7 15.0 4.0 1 1 3 4 4 4 0 RasGAP C-terminus TMPIT PF07851.13 EEQ40665.1 - 2.3 7.4 32.7 0.025 13.9 9.1 3.1 1 1 3 4 4 4 0 TMPIT-like protein HrpB7 PF09486.10 EEQ40665.1 - 3 8.2 35.8 0.39 11.1 10.2 3.8 2 1 2 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF948 PF06103.11 EEQ40665.1 - 3.7 7.9 15.6 0.056 13.7 1.3 3.6 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) MscS_porin PF12795.7 EEQ40665.1 - 4.4 6.8 43.0 2.3 7.7 9.2 2.6 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain SesA PF17107.5 EEQ40665.1 - 6.3 7.0 21.1 0.055 13.6 8.6 3.1 2 2 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases COQ7 PF03232.13 EEQ40666.1 - 1.2e-75 253.1 0.1 1.5e-75 252.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EEQ40666.1 - 0.0018 18.7 0.0 0.0049 17.3 0.0 1.7 2 0 0 2 2 2 1 Rubrerythrin YTH PF04146.15 EEQ40667.1 - 1.1e-34 119.8 0.1 1.9e-34 119.0 0.1 1.4 1 0 0 1 1 1 1 YT521-B-like domain PWI PF01480.17 EEQ40668.1 - 1.2e-16 60.7 0.5 2.1e-16 60.0 0.5 1.4 1 0 0 1 1 1 1 PWI domain Cullin_binding PF03556.15 EEQ40668.1 - 0.024 15.1 0.5 0.096 13.1 0.0 2.0 1 1 0 2 2 2 0 Cullin binding Pkinase PF00069.25 EEQ40669.1 - 7.5e-76 255.0 0.0 1.2e-75 254.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 EEQ40669.1 - 1.6e-55 186.6 0.0 3.3e-55 185.6 0.0 1.6 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 EEQ40669.1 - 6.5e-38 130.5 0.0 1.7e-37 129.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase UBA_2 PF08587.11 EEQ40669.1 - 7.6e-22 77.2 3.8 8.3e-22 77.0 1.7 2.1 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EEQ40669.1 - 5.7e-09 35.7 0.0 2.3e-08 33.7 0.0 1.9 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EEQ40669.1 - 0.00014 21.5 0.1 0.00026 20.6 0.1 1.4 1 0 0 1 1 1 1 RIO1 family YukC PF10140.9 EEQ40669.1 - 0.0009 18.2 0.2 0.0009 18.2 0.2 1.8 2 0 0 2 2 2 1 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 EEQ40669.1 - 0.0012 17.9 0.1 0.0027 16.7 0.1 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EEQ40669.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ40669.1 - 0.069 13.1 0.3 0.2 11.6 0.3 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Asp PF00026.23 EEQ40670.1 - 1e-55 189.4 10.8 1.2e-55 189.2 10.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ40670.1 - 4.7e-12 46.5 8.7 5.2e-05 23.6 3.5 3.2 2 1 1 3 3 3 3 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEQ40670.1 - 0.0056 17.3 0.2 2 9.1 0.1 2.7 2 1 0 2 2 2 2 Aspartyl protease SIR2 PF02146.17 EEQ40671.1 - 1.3e-36 126.2 0.0 1.1e-19 71.1 0.0 2.3 2 0 0 2 2 2 2 Sir2 family BLOC1_2 PF10046.9 EEQ40671.1 - 0.0077 16.5 0.2 0.032 14.5 0.1 2.0 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPP_enzyme_M PF00205.22 EEQ40671.1 - 0.028 14.2 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Pex24p PF06398.11 EEQ40672.1 - 5.1e-51 173.8 11.4 9.2e-41 140.0 2.2 2.3 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin DUF639 PF04842.12 EEQ40672.1 - 0.015 14.7 0.2 0.035 13.5 0.2 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) PPL5 PF18168.1 EEQ40672.1 - 3.1 7.0 7.4 5.9 6.1 7.4 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Zn_clus PF00172.18 EEQ40673.1 - 6e-06 26.3 6.8 6e-06 26.3 6.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec5 PF15469.6 EEQ40673.1 - 0.21 11.3 8.5 0.82 9.5 1.7 3.0 2 1 1 3 3 3 0 Exocyst complex component Sec5 EMC1_C PF07774.13 EEQ40674.1 - 1.4e-59 201.4 4.2 5.3e-59 199.5 3.2 2.3 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EEQ40674.1 - 0.00018 21.2 0.7 0.0019 17.9 0.1 2.7 2 1 0 2 2 2 1 PQQ-like domain HBB PF06777.11 EEQ40674.1 - 0.027 14.2 0.0 0.073 12.7 0.0 1.7 1 0 0 1 1 1 0 Helical and beta-bridge domain Pmp3 PF01679.17 EEQ40675.1 - 4.8e-20 71.5 8.5 5.6e-20 71.3 8.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4191 PF13829.6 EEQ40675.1 - 0.18 11.2 0.0 0.19 11.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) RPAP1_C PF08620.10 EEQ40676.1 - 1.9e-29 101.5 0.1 3.8e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EEQ40676.1 - 1.1e-17 63.5 7.6 3e-17 62.1 7.6 1.8 1 0 0 1 1 1 1 RPAP1-like, N-terminal Rx_N PF18052.1 EEQ40676.1 - 0.58 10.5 6.2 0.18 12.1 1.1 2.5 2 1 0 2 2 2 0 Rx N-terminal domain Pkinase PF00069.25 EEQ40677.1 - 1.3e-65 221.4 0.0 2.6e-65 220.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40677.1 - 3.1e-45 154.5 0.0 6.4e-45 153.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ40677.1 - 7.6e-06 25.0 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEQ40677.1 - 0.0083 15.5 0.0 0.028 13.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like TEA PF01285.18 EEQ40678.1 - 1.9e-07 31.0 0.6 4.4e-07 29.9 0.1 1.9 2 0 0 2 2 2 1 TEA/ATTS domain XPG_N PF00752.17 EEQ40679.1 - 2.7e-22 79.2 0.0 5.8e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EEQ40679.1 - 3.8e-21 75.2 0.0 8.3e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 EEQ40679.1 - 0.0007 19.1 0.2 0.0021 17.6 0.1 1.7 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EEQ40679.1 - 0.013 16.0 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold CGI-121 PF08617.10 EEQ40680.1 - 3.7e-33 115.0 0.2 4.7e-33 114.6 0.2 1.1 1 0 0 1 1 1 1 Kinase binding protein CGI-121 ZapA PF05164.13 EEQ40680.1 - 0.0099 16.3 0.2 0.021 15.2 0.2 1.6 1 0 0 1 1 1 1 Cell division protein ZapA RSS_P20 PF11757.8 EEQ40680.1 - 0.041 14.3 0.4 0.067 13.6 0.4 1.3 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like N-terminal domain FAST_2 PF08368.12 EEQ40680.1 - 0.041 14.7 0.8 1.5 9.6 0.2 2.2 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 MAT1 PF06391.13 EEQ40682.1 - 8.3e-58 195.6 29.5 1e-57 195.3 29.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EEQ40682.1 - 1.2e-27 95.5 10.4 2.1e-27 94.8 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ40682.1 - 0.00036 20.3 5.7 0.00071 19.4 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ40682.1 - 0.00053 20.3 7.1 0.00095 19.5 7.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EEQ40682.1 - 0.0012 18.7 4.1 0.0032 17.3 4.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ40682.1 - 0.0021 17.9 7.9 0.0043 16.9 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ndc1_Nup PF09531.10 EEQ40682.1 - 0.034 12.8 4.1 0.042 12.6 4.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RBM39linker PF15519.6 EEQ40682.1 - 0.046 14.8 2.6 0.12 13.5 2.6 1.7 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein zf-RING_UBOX PF13445.6 EEQ40682.1 - 0.11 12.5 7.3 0.25 11.4 7.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EEQ40682.1 - 0.81 9.7 10.0 19 5.3 10.5 2.5 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EEQ40682.1 - 5.4 7.0 9.7 52 3.8 0.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EEQ40682.1 - 7.5 6.4 10.8 1.2e+02 2.6 10.9 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain ArfGap PF01412.18 EEQ40683.1 - 1.7e-29 102.2 1.7 1.7e-29 102.2 1.7 2.3 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.29 EEQ40683.1 - 6e-15 55.6 0.4 1.7e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 PH domain BAR_3 PF16746.5 EEQ40683.1 - 2.5e-07 30.6 13.8 3.9e-07 30.0 12.8 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH_9 PF15410.6 EEQ40683.1 - 6.1e-06 26.6 0.1 4.4e-05 23.8 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_6 PF15406.6 EEQ40683.1 - 0.002 18.4 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain ATG16 PF08614.11 EEQ40683.1 - 0.1 12.8 2.5 1.2 9.3 0.5 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PolyA_pol PF01743.20 EEQ40684.1 - 5.3e-29 101.2 0.0 1.4e-28 99.8 0.0 1.8 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EEQ40684.1 - 6.7e-12 45.0 0.1 1.9e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EEQ40684.1 - 0.0022 18.0 0.3 0.0099 15.9 0.0 2.2 2 0 0 2 2 2 1 tRNA nucleotidyltransferase domain 2 putative EPSP_synthase PF00275.20 EEQ40685.1 - 5.2e-133 443.8 0.0 8e-133 443.1 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EEQ40685.1 - 4e-101 337.6 0.6 6.8e-101 336.8 0.6 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EEQ40685.1 - 6.3e-46 157.5 0.0 1.5e-45 156.2 0.0 1.7 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EEQ40685.1 - 8.5e-35 120.2 0.3 1.3e-33 116.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EEQ40685.1 - 1e-21 76.9 0.0 3.5e-21 75.2 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 EEQ40685.1 - 2.3e-10 40.6 0.1 5.1e-10 39.5 0.1 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 EEQ40685.1 - 2.4e-06 27.2 0.0 4.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EEQ40685.1 - 4.4e-06 26.8 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.19 EEQ40685.1 - 9e-06 24.7 1.3 3.7e-05 22.7 1.3 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 EEQ40685.1 - 0.0023 18.1 0.0 0.0062 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Lon_C PF05362.13 EEQ40685.1 - 0.024 14.2 0.0 0.098 12.2 0.0 1.9 2 0 0 2 2 2 0 Lon protease (S16) C-terminal proteolytic domain CoA_binding PF02629.19 EEQ40685.1 - 0.13 12.9 0.3 1.1 10.0 0.0 2.8 2 0 0 2 2 2 0 CoA binding domain PP2C_2 PF13672.6 EEQ40686.1 - 2.6e-09 37.0 0.0 5.7e-09 35.9 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 EEQ40686.1 - 3.7e-07 30.3 0.0 5.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EEQ40686.1 - 7.6e-05 22.5 0.9 0.053 13.1 0.3 2.4 1 1 1 2 2 2 2 Protein phosphatase 2C JIP_LZII PF16471.5 EEQ40688.1 - 0.12 12.6 3.6 0.26 11.5 3.6 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Endotoxin_N PF03945.14 EEQ40688.1 - 0.29 10.8 3.2 0.14 11.9 0.8 1.6 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain AAA_5 PF07728.14 EEQ40689.1 - 2.9e-124 409.5 0.8 5.1e-21 75.1 0.0 9.7 8 1 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EEQ40689.1 - 8.1e-53 177.1 1.4 3.3e-19 69.0 0.0 6.1 5 0 0 5 5 5 3 Midasin AAA lid domain AAA_lid_5 PF17865.1 EEQ40689.1 - 2.9e-33 114.1 0.2 8.9e-30 102.9 0.0 4.3 4 0 0 4 4 2 1 Midasin AAA lid domain AAA_3 PF07726.11 EEQ40689.1 - 9.5e-32 109.6 0.0 8.2e-08 32.2 0.0 8.5 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EEQ40689.1 - 1.1e-31 110.0 3.0 5.1e-05 23.7 0.0 7.6 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EEQ40689.1 - 7.3e-31 107.1 6.4 1.1e-06 28.2 0.1 6.9 7 0 0 7 7 6 5 P-loop containing dynein motor region Dynein_heavy PF03028.15 EEQ40689.1 - 2.1e-24 85.9 0.2 0.00016 21.8 0.0 9.7 10 1 0 10 10 8 4 Dynein heavy chain region D6 P-loop domain AAA_6 PF12774.7 EEQ40689.1 - 6.6e-23 81.2 0.4 0.013 14.5 0.4 9.3 9 0 0 9 9 9 6 Hydrolytic ATP binding site of dynein motor region AAA_16 PF13191.6 EEQ40689.1 - 2.8e-22 79.9 11.8 0.00079 19.8 0.3 8.1 6 2 0 6 6 6 5 AAA ATPase domain Sigma54_activat PF00158.26 EEQ40689.1 - 4.5e-22 78.5 0.6 0.00054 19.7 0.0 6.5 6 0 0 6 6 6 4 Sigma-54 interaction domain AAA_18 PF13238.6 EEQ40689.1 - 3.1e-20 73.1 4.1 0.013 16.0 0.1 7.2 6 0 0 6 6 6 4 AAA domain AAA_22 PF13401.6 EEQ40689.1 - 8.3e-20 71.5 0.2 0.011 16.0 0.0 8.1 6 0 0 6 6 6 4 AAA domain TsaE PF02367.17 EEQ40689.1 - 2.6e-19 69.4 5.8 0.007 16.4 0.2 6.6 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EEQ40689.1 - 9e-19 67.6 2.0 0.036 13.1 0.0 6.4 6 0 0 6 6 6 5 Type II/IV secretion system protein AAA_30 PF13604.6 EEQ40689.1 - 3.1e-17 62.9 1.6 0.026 14.2 0.2 7.3 7 1 0 7 7 6 5 AAA domain Sigma54_activ_2 PF14532.6 EEQ40689.1 - 9.6e-17 61.4 1.1 0.0062 16.7 0.0 6.7 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_14 PF13173.6 EEQ40689.1 - 2.5e-16 59.9 0.9 0.094 12.8 0.0 8.3 7 1 0 7 7 7 3 AAA domain RuvB_N PF05496.12 EEQ40689.1 - 1e-13 51.3 5.0 0.02 14.7 0.0 7.1 7 0 0 7 7 7 3 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EEQ40689.1 - 1.6e-13 51.0 1.2 0.017 15.3 0.0 6.5 6 0 0 6 6 6 2 AAA domain RNA_helicase PF00910.22 EEQ40689.1 - 9.4e-13 48.5 3.8 0.17 12.3 0.1 7.0 6 0 0 6 6 6 3 RNA helicase Zeta_toxin PF06414.12 EEQ40689.1 - 3.3e-12 46.1 5.1 0.67 9.2 0.2 7.0 7 0 0 7 7 7 4 Zeta toxin Rad17 PF03215.15 EEQ40689.1 - 4.3e-12 46.3 4.2 0.0024 17.8 0.1 6.6 6 0 0 6 6 6 1 Rad17 P-loop domain ABC_tran PF00005.27 EEQ40689.1 - 3.4e-11 43.8 9.7 0.0033 18.0 0.1 6.5 6 0 0 6 6 6 2 ABC transporter AAA_2 PF07724.14 EEQ40689.1 - 4e-11 43.3 1.0 0.32 11.1 0.2 6.9 6 1 0 6 6 6 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EEQ40689.1 - 4.2e-11 42.6 2.3 2 7.8 0.0 8.9 10 0 0 10 10 10 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EEQ40689.1 - 1e-10 41.6 0.3 2.1 8.0 0.0 6.7 6 0 0 6 6 6 1 IstB-like ATP binding protein NACHT PF05729.12 EEQ40689.1 - 7.3e-10 39.0 5.9 0.39 10.6 0.0 5.7 5 0 0 5 5 4 3 NACHT domain AAA_25 PF13481.6 EEQ40689.1 - 9.8e-10 38.3 1.9 0.45 10.1 0.0 6.4 7 0 0 7 7 6 2 AAA domain ATPase_2 PF01637.18 EEQ40689.1 - 2.1e-09 37.6 7.4 0.053 13.4 0.0 8.1 7 0 0 7 7 7 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EEQ40689.1 - 7.3e-09 35.7 12.6 0.087 12.7 0.7 6.2 6 0 0 6 6 5 3 RsgA GTPase AAA_29 PF13555.6 EEQ40689.1 - 4.4e-08 32.7 4.3 1.6 8.5 0.0 6.8 7 0 0 7 7 6 1 P-loop containing region of AAA domain PduV-EutP PF10662.9 EEQ40689.1 - 6.5e-08 32.4 8.5 0.063 13.0 0.1 5.9 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 EEQ40689.1 - 1.2e-07 31.2 3.8 0.074 12.2 0.1 5.2 6 0 0 6 6 4 2 Protein of unknown function (DUF815) AAA_19 PF13245.6 EEQ40689.1 - 1.7e-07 31.7 12.5 0.74 10.1 0.2 7.0 7 0 0 7 7 6 2 AAA domain AAA_24 PF13479.6 EEQ40689.1 - 5.6e-07 29.5 2.2 2.1 8.0 0.0 6.1 6 0 0 6 6 6 1 AAA domain TIP49 PF06068.13 EEQ40689.1 - 8.6e-07 28.5 2.0 1.1 8.3 0.1 5.1 5 0 0 5 5 4 1 TIP49 P-loop domain PhoH PF02562.16 EEQ40689.1 - 1.6e-06 27.7 5.0 0.095 12.1 0.0 5.1 5 0 0 5 5 4 2 PhoH-like protein AAA_28 PF13521.6 EEQ40689.1 - 1.6e-06 28.5 10.8 4.6 7.5 0.0 7.5 8 0 0 8 8 6 0 AAA domain Bac_DnaA PF00308.18 EEQ40689.1 - 4.5e-06 26.7 0.2 1.2 8.9 0.0 4.9 4 0 0 4 4 4 1 Bacterial dnaA protein NTPase_1 PF03266.15 EEQ40689.1 - 8e-06 25.9 8.6 1.1 9.2 0.4 5.7 5 0 0 5 5 5 1 NTPase AAA_9 PF12781.7 EEQ40689.1 - 8.8e-06 25.0 0.6 0.4 9.8 0.0 6.2 6 0 0 6 6 6 1 ATP-binding dynein motor region Viral_helicase1 PF01443.18 EEQ40689.1 - 8.8e-06 25.6 1.8 7.7 6.2 0.0 5.8 7 0 0 7 7 5 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 EEQ40689.1 - 9.8e-06 25.1 8.2 0.24 10.8 0.1 5.9 7 0 0 7 7 6 2 Bacterial TniB protein KAP_NTPase PF07693.14 EEQ40689.1 - 2e-05 24.0 6.4 0.14 11.4 0.1 5.8 6 0 0 6 6 6 1 KAP family P-loop domain ResIII PF04851.15 EEQ40689.1 - 6.8e-05 22.9 7.8 1.9 8.4 0.6 5.4 5 1 0 5 5 4 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 EEQ40689.1 - 7.8e-05 22.0 6.6 0.38 9.9 0.0 4.7 4 0 0 4 4 4 2 NB-ARC domain MCM PF00493.23 EEQ40689.1 - 8.9e-05 21.7 1.7 5.3 6.1 0.1 5.4 5 0 0 5 5 5 0 MCM P-loop domain ATP-synt_ab PF00006.25 EEQ40689.1 - 0.0001 22.0 0.0 1.3 8.7 0.0 4.1 2 1 1 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.6 EEQ40689.1 - 0.00011 22.6 4.0 4.9 7.6 0.0 5.7 5 0 0 5 5 4 0 AAA domain SRP54 PF00448.22 EEQ40689.1 - 0.00026 20.7 12.6 0.24 11.0 0.4 5.3 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain AAA_8 PF12780.7 EEQ40689.1 - 0.00058 19.3 1.4 2.1 7.6 0.0 5.5 6 0 0 6 6 5 1 P-loop containing dynein motor region D4 DEAD PF00270.29 EEQ40689.1 - 0.00092 19.0 0.8 28 4.4 0.1 5.3 5 0 0 5 5 4 0 DEAD/DEAH box helicase PRK PF00485.18 EEQ40689.1 - 0.0011 18.7 0.5 2.3 7.9 0.1 3.5 3 0 0 3 3 2 1 Phosphoribulokinase / Uridine kinase family PIF1 PF05970.14 EEQ40689.1 - 0.0013 18.0 7.1 1.1 8.4 0.0 5.5 6 0 0 6 6 5 1 PIF1-like helicase Roc PF08477.13 EEQ40689.1 - 0.0017 18.6 9.9 5.6 7.2 0.2 6.0 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase dNK PF01712.19 EEQ40689.1 - 0.0028 17.5 12.0 14 5.5 0.0 7.9 8 0 0 8 8 8 0 Deoxynucleoside kinase MMR_HSR1 PF01926.23 EEQ40689.1 - 0.0028 17.7 9.0 10 6.2 0.0 6.0 6 0 0 6 6 5 0 50S ribosome-binding GTPase IPT PF01745.16 EEQ40689.1 - 0.0033 16.8 1.9 58 2.9 0.0 5.3 5 0 0 5 5 4 0 Isopentenyl transferase tRNA_lig_kinase PF08303.11 EEQ40689.1 - 0.0075 16.4 1.9 1.4 9.0 0.0 4.0 3 0 0 3 3 3 1 tRNA ligase kinase domain Sigma_1s PF02454.16 EEQ40689.1 - 0.011 15.8 4.9 0.045 13.7 0.4 3.6 3 0 0 3 3 2 0 Sigma 1s protein CPT PF07931.12 EEQ40689.1 - 0.012 15.5 3.0 17 5.2 0.0 5.4 5 1 0 5 5 4 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 EEQ40689.1 - 0.02 14.0 0.4 7 5.6 0.0 4.0 4 0 0 4 4 4 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.6 EEQ40689.1 - 0.026 15.0 0.2 0.026 15.0 0.2 8.4 9 2 0 9 9 7 0 AAA domain FtsK_SpoIIIE PF01580.18 EEQ40689.1 - 0.032 13.6 2.5 23 4.3 0.1 4.7 5 0 0 5 5 5 0 FtsK/SpoIIIE family Torsin PF06309.11 EEQ40689.1 - 0.033 14.3 0.3 6.3 6.9 0.1 4.0 3 0 0 3 3 3 0 Torsin Microtub_bd PF16796.5 EEQ40689.1 - 0.064 13.2 3.4 5.9 6.8 0.0 4.8 6 0 0 6 6 4 0 Microtubule binding AAA_11 PF13086.6 EEQ40689.1 - 0.068 12.9 13.3 4.9 6.9 0.1 6.1 6 1 1 7 7 6 0 AAA domain CbiA PF01656.23 EEQ40689.1 - 0.23 11.5 8.1 19 5.3 0.1 5.1 5 0 0 5 5 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EEQ40689.1 - 0.32 9.9 1.9 22 3.9 0.3 3.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SKI PF01202.22 EEQ40689.1 - 0.58 10.3 4.6 1.8 8.7 0.0 3.8 4 0 0 4 4 2 0 Shikimate kinase cobW PF02492.19 EEQ40689.1 - 0.69 9.5 14.5 6.2 6.4 0.3 5.7 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EEQ40689.1 - 0.84 9.4 15.5 6.3 6.5 0.3 6.0 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein TrwB_AAD_bind PF10412.9 EEQ40689.1 - 2.3 7.0 6.4 5.1 5.9 0.2 3.9 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain ATPase PF06745.13 EEQ40689.1 - 2.6 7.3 14.7 13 5.0 0.1 5.8 7 0 0 7 7 7 0 KaiC Recep_L_domain PF01030.24 EEQ40690.1 - 2.6e-11 43.6 1.9 3e-05 24.1 0.1 3.6 1 1 1 3 3 3 3 Receptor L domain CTP_transf_like PF01467.26 EEQ40691.1 - 0.0014 18.9 0.0 0.0037 17.4 0.0 1.8 1 1 0 1 1 1 1 Cytidylyltransferase-like ATP-sulfurylase PF01747.17 EEQ40691.1 - 0.19 11.2 0.0 1.1 8.7 0.0 1.9 2 0 0 2 2 2 0 ATP-sulfurylase DUF4112 PF13430.6 EEQ40694.1 - 5.6e-28 97.3 0.4 8.7e-28 96.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DHHC PF01529.20 EEQ40696.1 - 9.1e-30 103.5 2.8 9.1e-30 103.5 2.8 3.3 4 0 0 4 4 4 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EEQ40696.1 - 3.2e-28 98.1 3.6 3e-12 46.9 0.4 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EEQ40696.1 - 1.1e-25 88.9 3.2 0.00017 21.9 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EEQ40696.1 - 1.1e-24 86.4 3.3 3.1e-10 40.4 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EEQ40696.1 - 2.1e-23 79.9 1.3 0.0013 19.1 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EEQ40696.1 - 7e-21 74.0 4.7 1.1e-05 25.6 0.4 5.1 2 2 3 5 5 5 4 Ankyrin repeats (many copies) DUF996 PF06195.13 EEQ40696.1 - 9.1 6.6 15.2 3.2 8.1 0.3 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF996) DNA_pol_A_exo1 PF01612.20 EEQ40697.1 - 0.001 18.8 0.0 0.0023 17.7 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease CHORD PF04968.12 EEQ40697.1 - 0.0012 19.5 1.6 0.0031 18.2 1.6 1.7 1 0 0 1 1 1 1 CHORD MutS_V PF00488.21 EEQ40698.1 - 8.8e-64 215.0 0.2 2.7e-63 213.4 0.1 1.9 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EEQ40698.1 - 3.5e-32 112.2 0.1 3.5e-32 112.2 0.1 2.2 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.20 EEQ40698.1 - 5.1e-32 110.5 0.0 1.6e-31 108.9 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EEQ40698.1 - 8.6e-15 55.2 0.0 2.6e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EEQ40698.1 - 1.5e-10 41.3 2.3 8.7e-10 38.8 0.3 2.9 2 0 0 2 2 2 1 MutS family domain IV AAA_29 PF13555.6 EEQ40698.1 - 0.043 13.5 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 EEQ40698.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4149 PF13664.6 EEQ40699.1 - 6.1e-20 71.5 2.3 1.5e-18 67.0 0.2 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4149) zf-C2H2 PF00096.26 EEQ40700.1 - 5.4e-09 36.0 11.0 0.0004 20.7 2.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ40700.1 - 2.3e-07 30.9 9.5 5.5e-07 29.7 4.8 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ40700.1 - 7.9e-06 26.3 10.2 0.025 15.4 1.4 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EEQ40700.1 - 0.016 15.6 5.2 0.41 11.1 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4736 PF15883.5 EEQ40700.1 - 0.053 13.3 0.3 0.26 11.0 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) zf_C2H2_ZHX PF18387.1 EEQ40700.1 - 0.059 13.0 4.4 2.5 7.8 0.2 2.8 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_jaz PF12171.8 EEQ40700.1 - 0.092 13.1 3.7 16 5.9 0.0 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding LIM PF00412.22 EEQ40700.1 - 0.43 10.9 2.6 1.2 9.4 2.7 1.7 1 1 0 1 1 1 0 LIM domain zf-C2H2_6 PF13912.6 EEQ40700.1 - 0.79 9.8 7.7 0.34 11.0 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Glutaredoxin PF00462.24 EEQ40701.1 - 1.1e-19 70.4 0.0 7.4e-18 64.5 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EEQ40701.1 - 1.6e-14 53.8 0.0 3.8e-14 52.5 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 EEQ40701.1 - 6.7e-05 23.1 0.0 0.017 15.4 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EEQ40701.1 - 0.0049 17.3 0.0 0.1 13.0 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Phosducin PF02114.16 EEQ40701.1 - 0.0063 15.5 0.0 0.0097 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosducin Thioredoxin_9 PF14595.6 EEQ40701.1 - 0.011 15.6 0.1 0.026 14.3 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin Rad17 PF03215.15 EEQ40702.1 - 1.4e-28 100.1 0.0 2.5e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EEQ40702.1 - 0.00033 21.1 0.0 0.00086 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EEQ40702.1 - 0.0028 18.2 0.2 0.01 16.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EEQ40702.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase Polyoma_lg_T_C PF06431.11 EEQ40702.1 - 0.035 13.0 0.1 4.2 6.1 0.4 2.4 2 0 0 2 2 2 0 Polyomavirus large T antigen C-terminus AAA_29 PF13555.6 EEQ40702.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EEQ40702.1 - 0.073 13.3 0.0 0.29 11.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain JmjC PF02373.22 EEQ40703.1 - 3.2e-39 133.9 2.7 1e-38 132.2 1.3 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 EEQ40703.1 - 1.4e-14 53.8 0.6 3.1e-14 52.6 0.6 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.6 EEQ40703.1 - 1.4e-10 41.3 2.8 1.4e-10 41.3 2.8 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EEQ40703.1 - 7.6e-10 38.9 1.7 7.6e-10 38.9 1.7 1.9 2 0 0 2 2 2 1 PHD-zinc-finger like domain DUF2465 PF10239.9 EEQ40705.1 - 0.0019 17.5 2.7 0.0023 17.2 2.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) Alpha-E PF04168.12 EEQ40705.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.3 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. CAF1A PF12253.8 EEQ40706.1 - 1.2e-20 73.4 10.7 1.2e-20 73.4 10.7 3.8 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A TetR_C_8 PF14278.6 EEQ40706.1 - 0.0011 19.0 0.4 0.0037 17.4 0.4 1.8 1 0 0 1 1 1 1 Transcriptional regulator C-terminal region DUF3336 PF11815.8 EEQ40707.1 - 3.3e-32 111.1 2.7 5e-32 110.5 2.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EEQ40707.1 - 7.8e-05 22.9 2.2 0.0001 22.5 1.1 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase DUF4386 PF14329.6 EEQ40707.1 - 0.05 13.5 0.1 0.05 13.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) MscL PF01741.18 EEQ40707.1 - 0.12 12.6 0.7 0.33 11.2 0.2 2.0 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL ELP6 PF09807.9 EEQ40709.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Elongation complex protein 6 DUF1968 PF09291.10 EEQ40709.1 - 0.014 15.4 0.3 0.04 14.0 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) ATPase PF06745.13 EEQ40709.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 KaiC zf-C2H2 PF00096.26 EEQ40710.1 - 0.33 11.5 8.1 2.9 8.5 0.4 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ40710.1 - 1.5 9.9 8.7 2.6 9.1 0.2 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger Ammonium_transp PF00909.21 EEQ40711.1 - 9.4e-35 120.1 7.3 1.3e-34 119.6 7.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Gti1_Pac2 PF09729.9 EEQ40712.1 - 1.6e-33 116.3 0.9 3e-27 95.9 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family LRR_6 PF13516.6 EEQ40713.1 - 0.00016 21.4 0.2 2.4 8.4 0.0 4.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 EEQ40713.1 - 0.00057 20.2 0.8 0.87 10.1 0.0 3.3 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) Cyclin_N PF00134.23 EEQ40714.1 - 5.9e-24 84.2 0.3 1.3e-23 83.1 0.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Hyphal_reg_CWP PF11765.8 EEQ40716.1 - 4.1e-73 246.2 13.4 4.1e-73 246.2 13.4 2.0 2 1 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal Bac_globin PF01152.21 EEQ40717.1 - 0.14 12.3 8.9 55 3.9 0.0 5.0 3 1 2 5 5 5 0 Bacterial-like globin POTRA_2 PF08479.11 EEQ40717.1 - 0.83 9.5 9.0 67 3.4 0.0 6.4 9 1 1 10 10 10 0 POTRA domain, ShlB-type PH_12 PF16457.5 EEQ40717.1 - 9.4 6.8 13.3 13 6.4 0.4 5.0 3 1 3 6 6 6 0 Pleckstrin homology domain SARA PF11409.8 EEQ40718.1 - 0.0037 17.4 10.6 2.2 8.6 0.2 5.9 6 0 0 6 6 6 3 Smad anchor for receptor activation (SARA) Sugar_tr PF00083.24 EEQ40719.1 - 5.4e-66 223.3 27.0 6.5e-66 223.0 27.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ40719.1 - 1.1e-20 73.9 22.2 1.4e-18 67.0 21.6 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ40719.1 - 0.0029 16.5 13.8 0.018 14.0 2.9 2.7 2 1 0 2 2 2 2 MFS_1 like family Epimerase PF01370.21 EEQ40720.1 - 1.5e-20 73.7 0.0 2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EEQ40720.1 - 3.1e-11 43.3 0.0 4.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EEQ40720.1 - 4.7e-11 42.2 0.0 6.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EEQ40720.1 - 2.1e-07 30.4 0.1 3.3e-06 26.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EEQ40720.1 - 4.4e-06 26.3 0.0 8.6e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EEQ40720.1 - 6e-05 22.3 0.1 0.00013 21.2 0.1 1.6 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EEQ40720.1 - 0.00014 21.8 0.1 0.00044 20.2 0.1 1.9 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EEQ40720.1 - 0.00077 19.1 0.2 0.022 14.3 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 EEQ40720.1 - 0.0009 19.2 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 KR domain PhoPQ_related PF10142.9 EEQ40720.1 - 0.058 12.0 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein RmlD_sub_bind PF04321.17 EEQ40720.1 - 0.098 11.7 0.1 0.22 10.6 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EEQ40720.1 - 0.11 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EEQ40720.1 - 0.13 12.4 0.5 0.44 10.7 0.2 2.1 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FMN_bind_2 PF04299.12 EEQ40721.1 - 1.4e-59 200.6 0.3 1.7e-59 200.3 0.3 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain DUF3465 PF11948.8 EEQ40721.1 - 0.031 14.1 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3465) GLEYA PF10528.9 EEQ40722.1 - 1.8e-15 57.1 0.1 1.6e-14 54.1 0.1 2.8 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.12 EEQ40722.1 - 1.6e-11 44.2 0.0 5.6e-11 42.4 0.0 2.0 1 0 0 1 1 1 1 PA14 domain Flocculin_t3 PF13928.6 EEQ40722.1 - 4.8e-11 43.0 16.2 4.8e-11 43.0 16.2 10.0 5 2 3 8 8 8 1 Flocculin type 3 repeat p450 PF00067.22 EEQ40723.1 - 7.1e-66 222.8 0.0 9.6e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase-like PF12876.7 EEQ40723.1 - 0.051 12.9 0.1 0.28 10.5 0.1 2.1 2 1 0 2 2 2 0 Sugar-binding cellulase-like SYS1 PF09801.9 EEQ40724.1 - 7.2e-53 178.6 12.4 8.5e-53 178.4 12.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DEAD PF00270.29 EEQ40725.1 - 3.9e-46 157.0 0.2 8.6e-46 155.9 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ40725.1 - 1.3e-28 99.5 0.3 8.9e-28 96.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PH_12 PF16457.5 EEQ40726.1 - 2.5e-31 109.0 0.1 5.2e-31 107.9 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_M48_N PF16491.5 EEQ40727.1 - 3.3e-60 203.1 6.7 7.3e-60 202.0 6.7 1.6 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EEQ40727.1 - 1.4e-38 132.7 0.0 2.1e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 SprT-like PF10263.9 EEQ40727.1 - 0.048 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 SprT-like family Peptidase_M78 PF06114.13 EEQ40727.1 - 0.18 11.8 0.2 0.57 10.1 0.2 1.8 1 0 0 1 1 1 0 IrrE N-terminal-like domain LUC7 PF03194.15 EEQ40728.1 - 2.9e-59 200.7 4.7 3.3e-59 200.6 4.7 1.0 1 0 0 1 1 1 1 LUC7 N_terminus HlyD_2 PF12700.7 EEQ40728.1 - 0.0014 17.4 3.1 0.0018 17.1 3.1 1.1 1 0 0 1 1 1 1 HlyD family secretion protein Seryl_tRNA_N PF02403.22 EEQ40728.1 - 0.41 10.9 6.2 4.5 7.5 0.2 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ArnB_C PF18677.1 EEQ40728.1 - 9.9 6.4 10.1 8.8 6.5 3.5 2.9 2 1 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain F-box-like PF12937.7 EEQ40729.1 - 2e-13 50.0 0.1 6.5e-13 48.3 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EEQ40729.1 - 1.3e-05 25.0 1.4 5.7e-05 22.9 0.6 2.7 2 1 0 2 2 2 1 F-box domain DUF762 PF05555.11 EEQ40729.1 - 0.067 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF762) F-box_4 PF15966.5 EEQ40729.1 - 0.12 12.2 0.8 0.27 11.1 0.1 1.9 2 0 0 2 2 2 0 F-box Glyco_hydro_72 PF03198.14 EEQ40730.1 - 2.6e-09 36.8 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_72 PF03198.14 EEQ40731.1 - 3.2e-68 230.3 2.3 3.8e-68 230.1 2.3 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EEQ40731.1 - 0.0012 18.3 0.3 0.0049 16.3 0.3 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M28 PF04389.17 EEQ40732.1 - 9.4e-40 136.4 0.0 1.5e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EEQ40732.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EEQ40732.1 - 0.00048 19.2 0.0 0.0025 16.9 0.0 1.9 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase URO-D PF01208.17 EEQ40733.1 - 3.3e-87 292.8 0.0 3.7e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF1818 PF08848.11 EEQ40733.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1818) bVLRF1 PF18826.1 EEQ40735.1 - 4.8e-61 205.0 1.4 8.5e-61 204.2 1.4 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_2 PF12796.7 EEQ40735.1 - 0.0001 22.8 0.1 0.00026 21.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EEQ40735.1 - 0.00024 21.4 0.0 0.0005 20.3 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ40735.1 - 0.0025 18.3 0.0 0.0061 17.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EEQ40735.1 - 0.0029 18.0 0.3 0.0064 16.9 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 EEQ40735.1 - 0.0066 16.9 0.1 0.016 15.7 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat MFS_1 PF07690.16 EEQ40736.1 - 8.4e-45 153.2 49.1 6.9e-43 146.9 52.1 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ40736.1 - 1.9e-17 62.9 29.6 3.1e-17 62.2 29.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ40736.1 - 3.6e-13 49.2 19.6 3.6e-13 49.2 19.6 3.5 3 1 1 4 4 4 1 Sugar (and other) transporter Pox_A14 PF05767.12 EEQ40736.1 - 9.3 6.5 11.7 0.5 10.6 1.0 3.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 MFS_1 PF07690.16 EEQ40737.1 - 8.2e-43 146.7 54.3 2.2e-41 141.9 55.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EEQ40737.1 - 9e-21 73.9 17.1 9e-21 73.9 17.1 1.8 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EEQ40737.1 - 2.5e-09 36.5 21.8 2.5e-09 36.5 21.8 3.4 4 0 0 4 4 4 1 Sugar (and other) transporter DUF2238 PF09997.9 EEQ40737.1 - 2.7 7.8 8.7 0.066 13.0 0.6 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2238) Pox_A14 PF05767.12 EEQ40737.1 - 8.8 6.6 10.5 0.32 11.2 0.4 3.5 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 SNF2_N PF00176.23 EEQ40738.1 - 4.5e-55 186.8 0.1 6.5e-55 186.2 0.1 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EEQ40738.1 - 2.4e-16 60.0 0.0 2e-15 57.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ40738.1 - 4.6e-12 46.3 0.0 8.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ40738.1 - 2.9e-06 27.2 0.0 5.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2428 PF10350.9 EEQ40740.1 - 1.4e-47 162.3 0.4 1.4e-47 162.3 0.4 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) DUF2659 PF10858.8 EEQ40740.1 - 0.028 14.1 0.2 0.083 12.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) HEAT PF02985.22 EEQ40740.1 - 0.1 12.9 0.2 13 6.4 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat SPG48 PF14764.6 EEQ40740.1 - 0.34 11.4 2.4 8 7.0 0.0 4.3 4 0 0 4 4 4 0 AP-5 complex subunit, vesicle trafficking RRM_1 PF00076.22 EEQ40742.1 - 0.00086 19.1 0.1 0.0023 17.7 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2854 PF11016.8 EEQ40742.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Alg14 PF08660.11 EEQ40743.1 - 6.7e-59 198.7 0.0 1.1e-58 198.1 0.0 1.3 1 1 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like DRMBL PF07522.14 EEQ40745.1 - 0.0019 18.4 0.1 0.0043 17.2 0.1 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EEQ40745.1 - 0.0029 17.1 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 EEQ40745.1 - 0.035 14.0 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain TFIIS_C PF01096.18 EEQ40746.1 - 4.5e-22 77.6 3.3 4.5e-22 77.6 3.3 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EEQ40746.1 - 4.3e-08 32.9 4.9 4.3e-08 32.9 4.9 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EEQ40746.1 - 0.013 15.5 0.4 0.013 15.5 0.4 3.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain IBR PF01485.21 EEQ40746.1 - 0.03 14.5 10.9 0.089 13.0 1.6 2.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Baculo_LEF5_C PF11792.8 EEQ40746.1 - 0.27 11.0 0.2 0.27 11.0 0.2 2.1 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain PhnA_Zn_Ribbon PF08274.12 EEQ40746.1 - 0.81 9.7 13.6 0.4 10.7 0.3 3.0 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zinc_ribbon_4 PF13717.6 EEQ40746.1 - 1.4 8.9 11.1 0.6 10.1 0.7 3.3 4 0 0 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.6 EEQ40746.1 - 4 7.4 11.1 0.14 12.1 1.9 2.7 3 0 0 3 3 3 0 Nudix N-terminal DpnI PF06044.12 EEQ40746.1 - 5 6.7 6.8 0.66 9.6 1.0 1.9 2 0 0 2 2 2 0 Dam-replacing family ORC2 PF04084.14 EEQ40747.1 - 5.1e-102 341.2 0.1 6.9e-102 340.7 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Pkinase PF00069.25 EEQ40748.1 - 3.3e-34 118.4 0.0 5.1e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40748.1 - 1.1e-20 74.1 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EEQ40748.1 - 9.9e-10 38.1 0.0 2.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EEQ40748.1 - 1.5e-05 24.5 0.0 3.6e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ40748.1 - 0.0041 16.1 0.0 0.0072 15.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEQ40748.1 - 0.0086 16.0 7.1 0.54 10.1 0.2 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EEQ40748.1 - 0.17 10.7 0.0 0.17 10.7 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase TPR_17 PF13431.6 EEQ40749.1 - 0.00012 22.1 0.6 0.0038 17.5 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ40749.1 - 0.0025 17.6 8.9 0.0055 16.5 0.2 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ40749.1 - 0.0029 18.1 1.8 0.0029 18.1 1.8 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ40749.1 - 0.0048 17.0 4.3 2.8 8.4 0.2 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ40749.1 - 0.024 14.7 9.2 0.2 11.7 0.4 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ40749.1 - 0.042 14.0 15.9 0.059 13.5 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ40749.1 - 0.18 12.0 3.2 0.31 11.3 0.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EEQ40749.1 - 0.71 9.6 5.3 4 7.2 0.1 3.6 4 0 0 4 4 4 0 TPR repeat TPR_9 PF13371.6 EEQ40749.1 - 1.8 8.8 14.8 0.087 13.0 0.5 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ40749.1 - 5 7.5 17.4 0.72 10.2 2.0 4.9 3 3 1 4 4 4 0 Tetratricopeptide repeat UPF0121 PF03661.13 EEQ40750.1 - 0.2 11.0 5.9 0.32 10.4 5.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) Thiolase_N PF00108.23 EEQ40753.1 - 1.4e-82 277.0 0.6 2e-82 276.5 0.6 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEQ40753.1 - 1.1e-46 157.5 0.3 2e-46 156.6 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EEQ40753.1 - 0.0008 19.1 0.6 0.018 14.6 0.0 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Cadherin_tail PF15974.5 EEQ40753.1 - 0.0075 16.6 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 Cadherin C-terminal cytoplasmic tail, catenin-binding region SelA PF03841.13 EEQ40753.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase ACP_syn_III PF08545.10 EEQ40753.1 - 0.21 11.5 1.5 25 4.8 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III LicD PF04991.13 EEQ40756.1 - 1.3e-28 100.7 0.1 5.2e-26 92.2 0.1 2.7 1 1 0 2 2 2 2 LicD family tRNA_m1G_MT PF01746.21 EEQ40758.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase Lum_binding PF00677.17 EEQ40760.1 - 3.7e-41 139.0 3.0 5.4e-21 74.4 0.1 2.1 2 0 0 2 2 2 2 Lumazine binding domain Proteasome PF00227.26 EEQ40761.1 - 1.4e-37 129.0 0.1 1.8e-37 128.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit HA2 PF04408.23 EEQ40762.1 - 1.7e-21 76.5 0.0 1.7e-21 76.5 0.0 4.3 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEQ40762.1 - 5.8e-18 65.0 0.0 1.4e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EEQ40762.1 - 7.8e-13 48.8 0.0 2.6e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EEQ40762.1 - 4.5e-12 46.1 0.1 1.3e-11 44.7 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EEQ40762.1 - 2.3e-07 30.7 0.0 4.5e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ40762.1 - 5.8e-06 26.6 0.0 2.3e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EEQ40762.1 - 0.00081 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EEQ40762.1 - 0.0042 17.4 0.0 0.0089 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EEQ40762.1 - 0.025 14.6 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain EPL1 PF10513.9 EEQ40762.1 - 0.033 14.6 27.9 1.2 9.5 1.7 3.2 2 1 0 2 2 2 0 Enhancer of polycomb-like ATPase PF06745.13 EEQ40762.1 - 0.05 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 EEQ40762.1 - 0.078 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 EEQ40762.1 - 0.086 12.3 0.0 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region SRP54 PF00448.22 EEQ40762.1 - 0.1 12.2 0.1 0.25 11.0 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 EEQ40762.1 - 0.5 10.1 0.0 0.5 10.1 0.0 4.2 3 1 1 4 4 3 0 AAA domain DUF2370 PF10176.9 EEQ40762.1 - 1 9.0 13.6 0.093 12.4 3.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2370) ABC_tran PF00005.27 EEQ40762.1 - 3.4 8.2 12.5 0.69 10.4 0.1 4.0 3 1 0 3 3 3 0 ABC transporter FAM60A PF15396.6 EEQ40762.1 - 3.9 7.4 26.6 2.9 7.8 13.3 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Presenilin PF01080.17 EEQ40762.1 - 5.5 5.6 35.1 0.27 9.9 16.7 2.2 2 0 0 2 2 2 0 Presenilin Kinesin PF00225.23 EEQ40762.1 - 6.1 5.7 18.4 2.4 7.0 4.3 2.3 2 0 0 2 2 2 0 Kinesin motor domain DUF812 PF05667.11 EEQ40764.1 - 7.8e-05 21.8 9.1 9e-05 21.5 9.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) PID PF00640.23 EEQ40764.1 - 0.32 11.0 5.5 1.3 9.1 2.9 2.2 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) DUF4968 PF16338.5 EEQ40764.1 - 2 8.8 6.5 0.15 12.3 0.5 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4968) Cellulase PF00150.18 EEQ40765.1 - 3.5e-11 43.1 0.0 3.3e-06 26.7 0.0 2.4 3 0 0 3 3 3 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EEQ40765.1 - 4.3e-11 43.2 0.0 1.2e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain DNA_primase_S PF01896.19 EEQ40766.1 - 2.8e-63 213.1 0.3 4.1e-63 212.6 0.3 1.2 1 0 0 1 1 1 1 DNA primase small subunit DUF5067 PF16729.5 EEQ40767.1 - 0.015 15.2 1.6 0.015 15.2 1.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5067) WD40 PF00400.32 EEQ40770.1 - 3e-11 43.7 13.6 0.0086 16.9 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ40770.1 - 2.4e-09 37.3 1.1 0.0015 18.8 0.3 4.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EEQ40770.1 - 2.3e-06 27.4 7.7 1.9e-05 24.4 3.8 2.7 1 1 1 2 2 2 1 PQQ-like domain PQQ PF01011.21 EEQ40770.1 - 4.3e-05 23.2 0.2 0.032 14.2 0.1 3.9 3 0 0 3 3 3 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 EEQ40770.1 - 0.14 11.1 0.1 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 EEQ40770.1 - 1.9 9.1 18.1 5.8 7.5 0.0 6.0 6 1 1 7 7 7 0 PQQ-like domain Oxidored_FMN PF00724.20 EEQ40771.1 - 1.8e-90 303.7 0.0 2.1e-90 303.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family XET_C PF06955.12 EEQ40771.1 - 0.048 13.5 0.2 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Xyloglucan endo-transglycosylase (XET) C-terminus GlutR_dimer PF00745.20 EEQ40771.1 - 0.14 12.6 0.2 0.41 11.1 0.0 1.8 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Trypan_PARP PF05887.11 EEQ40773.1 - 0.00055 19.9 0.5 0.0008 19.4 0.5 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.13 EEQ40773.1 - 0.38 9.2 4.3 0.48 8.8 4.3 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SelP_N PF04592.14 EEQ40773.1 - 9 5.6 9.1 16 4.8 9.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Asp PF00026.23 EEQ40774.1 - 7.2e-13 48.6 2.3 1.7e-12 47.4 2.3 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease DUF5577 PF17740.1 EEQ40774.1 - 0.0088 15.8 2.9 0.013 15.2 2.9 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5577) KH_8 PF17903.1 EEQ40775.1 - 2.3e-31 107.7 0.0 7.6e-31 106.0 0.0 2.0 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EEQ40775.1 - 0.0028 17.4 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 KH domain GAGA_bind PF06217.12 EEQ40775.1 - 0.025 14.9 24.0 0.036 14.4 24.0 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 EEQ40775.1 - 3.5 7.4 30.5 5.6 6.7 30.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Afi1 PF07792.12 EEQ40775.1 - 6.6 7.2 20.4 7.8e+02 0.5 20.4 2.4 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking TPR_MLP1_2 PF07926.12 EEQ40776.1 - 0.013 15.6 5.1 0.024 14.7 2.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein MRC1 PF09444.10 EEQ40777.1 - 4.9e-33 114.7 19.9 4.9e-33 114.7 19.9 7.2 4 3 3 7 7 7 1 MRC1-like domain CagZ PF09053.10 EEQ40777.1 - 0.22 11.1 2.5 0.4 10.3 2.5 1.3 1 0 0 1 1 1 0 CagZ S-AdoMet_synt_C PF02773.16 EEQ40778.1 - 1.4e-66 222.7 0.4 2.6e-66 221.8 0.0 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EEQ40778.1 - 1.7e-45 154.1 0.0 3.2e-45 153.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EEQ40778.1 - 1e-44 151.2 0.5 1.9e-44 150.4 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EEQ40778.1 - 0.028 13.2 0.3 0.15 10.8 0.2 2.0 1 1 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Trefoil PF00088.18 EEQ40779.1 - 0.048 13.6 5.5 0.096 12.6 5.5 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain PAP2 PF01569.21 EEQ40780.1 - 2.7e-05 24.0 0.3 0.00014 21.7 0.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily Sugar_tr PF00083.24 EEQ40782.1 - 7.9e-42 143.7 12.6 1.2e-41 143.1 12.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ40782.1 - 8.9e-21 74.2 27.8 2.7e-18 66.0 17.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Myosin_head PF00063.21 EEQ40783.1 - 2.8e-259 861.9 6.1 2.8e-259 861.9 6.1 3.6 3 1 0 4 4 4 1 Myosin head (motor domain) Myosin_N PF02736.19 EEQ40783.1 - 7e-07 29.0 2.7 1.7e-06 27.7 2.7 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain bZIP_1 PF00170.21 EEQ40783.1 - 0.0053 16.8 3.5 0.0053 16.8 3.5 19.9 11 5 10 21 21 21 5 bZIP transcription factor AAA_22 PF13401.6 EEQ40783.1 - 0.28 11.5 0.0 0.28 11.5 0.0 4.9 4 1 0 4 4 4 0 AAA domain AAA_19 PF13245.6 EEQ40783.1 - 0.97 9.8 0.0 0.97 9.8 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 EEQ40783.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.7 5 0 0 5 5 5 0 AAA ATPase domain MLD PF11647.8 EEQ40783.1 - 3.7 7.9 12.8 0.072 13.4 1.4 4.2 3 0 0 3 3 3 0 Membrane Localization Domain Cyclin_N PF00134.23 EEQ40786.1 - 5.8e-40 136.0 1.8 1.2e-39 135.0 0.6 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EEQ40786.1 - 5.1e-08 33.0 0.5 1.4e-07 31.6 0.5 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cpn60_TCP1 PF00118.24 EEQ40787.1 - 4.3e-157 523.7 2.7 4.9e-157 523.5 2.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PNTB_4TM PF12769.7 EEQ40787.1 - 0.036 14.5 0.2 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 4TM region of pyridine nucleotide transhydrogenase, mitoch Ribosomal_L31 PF01197.18 EEQ40788.1 - 0.0015 18.7 0.0 0.006 16.8 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein L31 AAA_22 PF13401.6 EEQ40790.1 - 0.053 13.8 0.2 2.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sec10 PF07393.11 EEQ40791.1 - 9.7e-69 232.5 21.3 1.8e-68 231.6 21.3 1.3 1 1 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 EEQ40791.1 - 0.0035 17.2 0.0 0.0079 16.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Vps8 PF12816.7 EEQ40791.1 - 0.029 13.9 2.2 0.089 12.3 0.1 2.6 3 0 0 3 3 3 0 Golgi CORVET complex core vacuolar protein 8 F-box-like PF12937.7 EEQ40791.1 - 0.031 14.2 0.1 0.097 12.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like DUF3040 PF11239.8 EEQ40792.1 - 0.064 13.5 0.2 4.1 7.8 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) TraG-D_C PF12696.7 EEQ40792.1 - 0.95 9.5 4.6 0.29 11.1 0.1 2.3 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DDHD PF02862.17 EEQ40792.1 - 5.1 7.2 8.7 8.1 6.5 0.8 3.2 2 1 0 2 2 2 0 DDHD domain Radical_SAM PF04055.21 EEQ40793.1 - 0.25 11.7 0.3 0.25 11.7 0.3 2.0 2 0 0 2 2 2 0 Radical SAM superfamily PAP_central PF04928.17 EEQ40794.1 - 4.5e-110 366.5 0.0 6e-110 366.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EEQ40794.1 - 3.3e-51 173.3 0.0 6.1e-51 172.4 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EEQ40794.1 - 3.8e-15 56.0 0.7 8.6e-15 54.8 0.1 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 EEQ40794.1 - 0.018 15.1 0.0 0.073 13.2 0.0 2.0 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase Nrap_D2 PF17403.2 EEQ40794.1 - 0.055 13.2 0.1 0.17 11.7 0.1 1.8 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain MATalpha_HMGbox PF04769.12 EEQ40795.1 - 1.4e-15 57.2 0.1 1.7e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box PI3_PI4_kinase PF00454.27 EEQ40796.1 - 7.2e-33 114.4 2.2 1.8e-32 113.2 0.2 2.5 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 EEQ40796.1 - 6.4e-17 61.2 0.1 2.1e-16 59.6 0.1 2.0 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 EEQ40796.1 - 7e-05 22.3 1.2 7e-05 22.3 1.2 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) OST-HTH PF12872.7 EEQ40796.1 - 0.081 12.8 0.1 0.34 10.8 0.1 2.2 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Oxysterol_BP PF01237.18 EEQ40797.1 - 3.1e-84 283.0 2.2 1.1e-81 274.6 2.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein HCR PF07111.12 EEQ40797.1 - 0.013 13.6 0.3 0.018 13.1 0.3 1.1 1 0 0 1 1 1 0 Alpha helical coiled-coil rod protein (HCR) Peptidase_M16_C PF05193.21 EEQ40799.1 - 8.8e-35 120.4 0.0 1.9e-34 119.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EEQ40799.1 - 2.9e-32 111.7 0.0 6.6e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Presenilin PF01080.17 EEQ40800.1 - 0.0047 15.8 7.8 0.0063 15.3 7.8 1.1 1 0 0 1 1 1 1 Presenilin DDHD PF02862.17 EEQ40800.1 - 0.0072 16.5 0.9 0.01 16.0 0.9 1.3 1 0 0 1 1 1 1 DDHD domain RNA_pol_Rpc4 PF05132.14 EEQ40800.1 - 0.056 13.9 12.3 0.1 13.0 12.3 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 FAM91_C PF14648.6 EEQ40800.1 - 0.058 12.2 2.3 0.088 11.6 2.3 1.2 1 0 0 1 1 1 0 FAM91 C-terminus SAPS PF04499.15 EEQ40800.1 - 0.067 12.0 7.8 0.1 11.4 7.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.11 EEQ40800.1 - 0.14 10.6 17.3 0.19 10.2 17.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Merozoite_SPAM PF07133.11 EEQ40800.1 - 0.16 12.0 44.0 0.26 11.2 44.0 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2052 PF09747.9 EEQ40800.1 - 0.2 11.7 25.3 0.34 11.0 25.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Zip PF02535.22 EEQ40800.1 - 0.23 10.6 7.2 0.34 10.1 7.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SpoIIP PF07454.11 EEQ40800.1 - 0.44 10.0 21.1 0.73 9.2 21.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NARP1 PF12569.8 EEQ40800.1 - 0.57 9.0 21.9 1 8.2 21.9 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CPSF100_C PF13299.6 EEQ40800.1 - 0.72 10.0 15.6 1.3 9.2 15.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4569 PF15133.6 EEQ40800.1 - 0.75 9.5 11.6 1.3 8.7 11.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Tim54 PF11711.8 EEQ40800.1 - 0.9 8.3 22.8 1.4 7.7 22.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SLC12 PF03522.15 EEQ40800.1 - 1.2 8.1 13.4 1.7 7.6 13.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 CDC45 PF02724.14 EEQ40800.1 - 1.4 7.1 24.5 2.1 6.5 24.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4366 PF14283.6 EEQ40800.1 - 1.9 8.5 18.3 35 4.4 18.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) RP-C_C PF11800.8 EEQ40800.1 - 2.1 8.4 8.9 3.8 7.6 7.9 1.8 2 0 0 2 2 2 0 Replication protein C C-terminal region SDA1 PF05285.12 EEQ40800.1 - 2.2 7.6 34.0 3.2 7.1 34.0 1.1 1 0 0 1 1 1 0 SDA1 Membralin PF09746.9 EEQ40800.1 - 2.3 7.2 6.0 3.1 6.8 6.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein RR_TM4-6 PF06459.12 EEQ40800.1 - 2.4 7.9 27.2 3.6 7.3 27.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF913 PF06025.12 EEQ40800.1 - 2.4 7.0 11.9 3.9 6.4 11.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF262 PF03235.14 EEQ40800.1 - 2.7 8.1 9.1 4.5 7.4 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF262 PIEZO PF15917.5 EEQ40800.1 - 3.1 7.2 14.0 5.1 6.5 14.0 1.2 1 0 0 1 1 1 0 Piezo GAGA_bind PF06217.12 EEQ40800.1 - 3.2 7.9 12.2 4.8 7.4 12.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.12 EEQ40800.1 - 3.3 5.8 30.5 4.4 5.4 30.5 1.1 1 0 0 1 1 1 0 Nop14-like family MCM_bind PF09739.9 EEQ40800.1 - 4.2 5.7 15.9 7.4 4.9 15.9 1.3 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF2151 PF10221.9 EEQ40800.1 - 4.4 5.8 16.9 5.9 5.3 16.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Endostatin PF06482.11 EEQ40800.1 - 5.1 6.5 7.8 8.6 5.7 6.8 1.8 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin TP53IP5 PF15331.6 EEQ40800.1 - 5.5 7.1 11.7 8.1 6.5 11.7 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 NPR3 PF03666.13 EEQ40800.1 - 5.6 5.6 16.9 8.3 5.1 16.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_11 PF13086.6 EEQ40800.1 - 5.7 6.6 12.9 8.6 6.1 12.9 1.2 1 0 0 1 1 1 0 AAA domain CKAP2_C PF15297.6 EEQ40800.1 - 8.6 5.3 22.8 14 4.6 22.8 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Coilin_N PF15862.5 EEQ40800.1 - 8.9 6.1 21.0 16 5.3 21.0 1.4 1 0 0 1 1 1 0 Coilin N-terminus RPN2_C PF18004.1 EEQ40800.1 - 9.2 6.2 28.7 21 5.0 28.7 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain HLH PF00010.26 EEQ40801.1 - 1.9e-16 59.8 0.2 3.8e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3621 PF12285.8 EEQ40801.1 - 0.021 15.2 3.0 0.049 14.0 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3621) Ribosomal_L11_N PF03946.14 EEQ40802.1 - 0.31 10.9 1.4 0.57 10.1 1.4 1.4 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain p450 PF00067.22 EEQ40803.1 - 3.1e-95 319.6 0.0 3.6e-95 319.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GHMP_kinases_N PF00288.26 EEQ40805.1 - 2.2e-10 40.6 0.2 4.2e-10 39.7 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEQ40805.1 - 0.0018 18.6 0.0 0.0051 17.1 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal AIM5 PF17050.5 EEQ40805.1 - 0.17 12.7 0.0 0.41 11.5 0.0 1.6 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 Bac_surface_Ag PF01103.23 EEQ40806.1 - 1.1e-08 35.0 7.2 1.7e-08 34.4 7.2 1.3 1 0 0 1 1 1 1 Surface antigen RabGAP-TBC PF00566.18 EEQ40807.1 - 4.9e-19 68.9 0.1 4.9e-19 68.9 0.1 1.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Elf1 PF05129.13 EEQ40808.1 - 8.5e-30 102.6 3.6 1.1e-29 102.3 3.6 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 EEQ40808.1 - 0.041 14.0 2.1 0.14 12.3 2.2 1.8 1 1 1 2 2 2 0 Zinc ribbon domain Ribosomal_L37ae PF01780.19 EEQ40808.1 - 0.084 13.0 0.8 0.14 12.2 0.8 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family zf-C2H2_2 PF12756.7 EEQ40808.1 - 0.1 12.9 3.6 0.73 10.2 0.7 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) EST1_DNA_bind PF10373.9 EEQ40808.1 - 0.11 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain zf-FCS PF06467.14 EEQ40808.1 - 0.19 11.7 5.2 2.1 8.4 5.6 2.1 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif LRR_4 PF12799.7 EEQ40810.1 - 0.068 13.6 21.0 0.1 13.1 1.0 5.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) YtxH PF12732.7 EEQ40810.1 - 0.69 10.5 2.5 0.73 10.4 0.3 2.3 2 0 0 2 2 2 0 YtxH-like protein LRR_1 PF00560.33 EEQ40810.1 - 3.3 8.6 16.3 2.3 9.1 0.2 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 EEQ40810.1 - 5.9 7.2 11.0 19 5.6 0.4 5.6 7 0 0 7 7 7 0 Leucine Rich repeat SRP54 PF00448.22 EEQ40811.1 - 2.1e-78 262.4 2.1 6.7e-78 260.8 0.8 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EEQ40811.1 - 4.3e-29 101.0 5.4 4.3e-29 101.0 5.4 3.6 3 1 0 3 3 1 1 Signal peptide binding domain SRP54_N PF02881.19 EEQ40811.1 - 6.2e-16 58.4 2.0 1.7e-15 57.0 2.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EEQ40811.1 - 7.8e-07 28.9 2.7 0.00057 19.5 1.1 3.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 EEQ40811.1 - 9.7e-05 22.4 0.0 0.00051 20.1 0.0 2.2 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EEQ40811.1 - 0.0003 21.0 0.1 0.0012 19.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain MeaB PF03308.16 EEQ40811.1 - 0.0014 17.6 0.4 0.01 14.8 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EEQ40811.1 - 0.0023 17.8 0.0 0.0079 16.1 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.6 EEQ40811.1 - 0.0039 16.9 0.5 0.015 15.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EEQ40811.1 - 0.011 15.2 3.1 12 5.3 0.0 3.9 4 0 0 4 4 4 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EEQ40811.1 - 0.012 15.7 0.5 0.079 13.1 0.0 2.6 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_31 PF13614.6 EEQ40811.1 - 0.012 15.6 0.8 0.11 12.4 0.1 2.5 1 1 1 2 2 2 0 AAA domain APS_kinase PF01583.20 EEQ40811.1 - 0.012 15.6 0.4 0.039 13.9 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase MipZ PF09140.11 EEQ40811.1 - 0.029 13.7 0.1 6.1 6.1 0.0 2.4 2 0 0 2 2 2 0 ATPase MipZ AAA_18 PF13238.6 EEQ40811.1 - 0.035 14.6 0.4 0.22 12.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.6 EEQ40811.1 - 0.044 14.2 0.1 0.044 14.2 0.1 2.5 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.15 EEQ40811.1 - 0.14 12.1 1.8 0.49 10.3 0.2 2.4 1 1 1 2 2 2 0 NTPase AAA_16 PF13191.6 EEQ40811.1 - 0.17 12.3 0.0 0.52 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.17 EEQ40811.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein STI1 PF17830.1 EEQ40811.1 - 1.1 9.3 43.9 1.2 9.1 24.9 3.5 3 0 0 3 3 3 0 STI1 domain XPC-binding PF09280.11 EEQ40811.1 - 8 6.3 27.0 6.3 6.6 2.3 3.6 2 1 1 3 3 3 0 XPC-binding domain ArsA_ATPase PF02374.15 EEQ40811.1 - 8.6 5.4 13.0 2.2 7.4 0.1 4.1 4 0 0 4 4 4 0 Anion-transporting ATPase Red1 PF07964.11 EEQ40813.1 - 1.3 7.2 3.6 1.7 6.8 3.6 1.1 1 0 0 1 1 1 0 Rec10 / Red1 DUF5539 PF17693.1 EEQ40814.1 - 0.2 11.3 10.3 0.3 10.7 10.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Peptidase_A22B PF04258.13 EEQ40816.1 - 2.9e-44 151.7 0.1 4.7e-44 151.0 0.1 1.3 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EEQ40816.1 - 8.3e-06 25.5 0.1 8.3e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Nucleos_tra2_C PF07662.13 EEQ40816.1 - 0.065 13.1 0.2 0.18 11.6 0.2 1.7 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus HCV_NS4a PF01006.20 EEQ40816.1 - 3 7.7 6.7 0.4 10.5 1.0 2.6 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a Cwf_Cwc_15 PF04889.12 EEQ40816.1 - 7 6.3 7.9 10 5.8 7.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein KH_1 PF00013.29 EEQ40819.1 - 1.1e-35 121.2 2.0 4.6e-12 45.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EEQ40819.1 - 5.5e-08 32.6 5.2 0.049 13.5 0.0 4.1 4 1 0 4 4 4 3 KH domain KH_5 PF13184.6 EEQ40819.1 - 2.7e-07 30.6 2.8 0.12 12.4 0.1 3.3 3 0 0 3 3 3 3 NusA-like KH domain KH_2 PF07650.17 EEQ40819.1 - 3.5e-07 30.0 3.4 0.34 10.8 0.2 3.3 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EEQ40819.1 - 0.029 14.4 0.0 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 KH-like RNA-binding domain GAF_2 PF13185.6 EEQ40822.1 - 9.2e-17 61.6 0.1 1.6e-16 60.9 0.1 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EEQ40822.1 - 1.8e-09 38.3 0.1 2.1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EEQ40822.1 - 1.3e-05 25.6 0.0 1.6e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain CRT10 PF08728.10 EEQ40824.1 - 8e-119 397.9 8.6 4.7e-76 256.5 0.0 3.0 1 1 2 3 3 3 2 CRT10 Macoilin PF09726.9 EEQ40824.1 - 0.083 11.4 4.2 0.15 10.6 4.2 1.3 1 0 0 1 1 1 0 Macoilin family BES1_N PF05687.13 EEQ40824.1 - 2.5 8.5 6.9 6.7 7.1 6.9 1.7 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal CENP-C_C PF11699.8 EEQ40825.1 - 2.9e-21 75.4 0.2 5e-21 74.7 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 EEQ40825.1 - 0.00019 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.18 EEQ40825.1 - 0.18 11.7 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase RL10P_insert PF17777.1 EEQ40826.1 - 2.7e-19 68.9 0.0 4.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EEQ40826.1 - 1.3e-17 63.8 0.0 2.3e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Complex1_LYR PF05347.15 EEQ40829.1 - 1.1e-10 41.4 0.9 1.7e-10 40.8 0.9 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EEQ40829.1 - 0.039 14.7 0.4 0.066 14.0 0.3 1.4 1 1 0 1 1 1 0 Complex1_LYR-like CH PF00307.31 EEQ40830.1 - 4.2e-82 271.5 0.0 5.7e-22 78.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EEQ40830.1 - 2.9e-06 27.0 0.0 0.73 9.7 0.0 4.3 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.6 EEQ40830.1 - 6.6e-05 23.3 2.1 0.00012 22.4 0.6 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EEQ40830.1 - 0.00096 18.5 0.5 0.064 12.8 0.0 3.1 3 0 0 3 3 3 1 EF hand CH_2 PF06294.11 EEQ40830.1 - 0.00096 19.2 0.1 7.2 6.8 0.0 3.9 4 1 0 4 4 4 2 CH-like domain in sperm protein EF-hand_6 PF13405.6 EEQ40830.1 - 0.0049 16.7 0.3 12 6.1 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain Pep3_Vps18 PF05131.14 EEQ40831.1 - 4.5e-22 78.5 3.9 2.2e-21 76.2 0.1 3.5 3 1 0 3 3 3 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 EEQ40831.1 - 0.00011 22.6 0.6 0.00049 20.5 0.6 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 EEQ40831.1 - 0.00044 19.8 1.7 0.001 18.6 1.7 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 EEQ40831.1 - 0.0033 17.4 3.2 0.0081 16.2 3.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Clathrin PF00637.20 EEQ40831.1 - 0.0034 17.3 1.2 0.0034 17.3 1.2 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.6 EEQ40831.1 - 0.0051 17.1 3.8 0.0051 17.1 3.8 1.8 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 EEQ40831.1 - 0.0088 16.1 0.2 0.021 14.9 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EEQ40831.1 - 0.012 15.4 8.6 0.029 14.1 8.6 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 EEQ40831.1 - 0.038 14.3 1.6 0.099 12.9 1.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EEQ40831.1 - 0.045 13.6 3.7 0.1 12.5 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ40831.1 - 0.25 11.3 3.1 0.53 10.2 3.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EEQ40831.1 - 0.48 10.3 3.5 1.2 9.1 3.5 1.6 1 0 0 1 1 1 0 PHD-finger Spb1_C PF07780.12 EEQ40832.1 - 2.5e-81 272.3 21.2 2.5e-81 272.3 21.2 3.5 3 1 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EEQ40832.1 - 1.7e-54 184.6 0.0 3.7e-54 183.5 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EEQ40832.1 - 2.4e-41 141.3 17.3 2.4e-41 141.3 17.3 5.7 4 2 0 4 4 4 1 Domain of unknown function (DUF3381) APC_rep PF18797.1 EEQ40832.1 - 7.3 7.6 11.9 0.38 11.7 0.5 3.4 3 0 0 3 3 3 0 Adenomatous polyposis coli (APC) repeat TFIIB PF00382.19 EEQ40834.1 - 2.1e-44 149.4 0.2 1.9e-23 82.3 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EEQ40834.1 - 3.1e-13 49.0 1.0 5.6e-13 48.2 1.0 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_5 PF01022.20 EEQ40834.1 - 0.0017 18.2 0.0 0.0043 16.9 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory protein, arsR family RB_B PF01857.20 EEQ40834.1 - 0.0076 16.3 0.1 0.018 15.0 0.1 1.6 1 1 1 2 2 2 1 Retinoblastoma-associated protein B domain zf-ribbon_3 PF13248.6 EEQ40834.1 - 0.0084 15.5 0.8 0.2 11.1 0.0 2.5 2 0 0 2 2 2 1 zinc-ribbon domain HTH_34 PF13601.6 EEQ40834.1 - 0.049 13.8 0.1 14 6.0 0.1 2.5 2 0 0 2 2 2 0 Winged helix DNA-binding domain Cyclin_C PF02984.19 EEQ40834.1 - 0.18 11.9 0.0 2.4 8.3 0.0 2.2 1 1 1 2 2 2 0 Cyclin, C-terminal domain ATP_transf PF09830.9 EEQ40835.1 - 2e-18 66.3 0.0 3.6e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 EEQ40835.1 - 0.00044 20.9 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 HIT domain DUF4931 PF16285.5 EEQ40835.1 - 0.0062 15.9 0.0 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 EEQ40835.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) UCR_14kD PF02271.16 EEQ40836.1 - 1.5e-27 95.4 0.1 1.8e-27 95.2 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.27 EEQ40837.1 - 1.5e-58 194.7 3.4 1.1e-18 66.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ANTH PF07651.16 EEQ40838.1 - 1.6e-74 250.4 0.0 1.6e-74 250.4 0.0 3.7 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.17 EEQ40838.1 - 5.7e-53 179.3 7.3 5.7e-53 179.3 7.3 6.2 4 1 1 6 6 6 2 I/LWEQ domain Spc7 PF08317.11 EEQ40838.1 - 0.00052 19.0 18.1 0.00052 19.0 18.1 4.6 2 1 2 4 4 4 1 Spc7 kinetochore protein TcdB_N PF12918.7 EEQ40838.1 - 0.00056 20.1 3.1 0.00056 20.1 3.1 3.8 3 1 0 3 3 3 1 TcdB toxin N-terminal helical domain ABC_tran_CTD PF16326.5 EEQ40838.1 - 0.0013 19.0 3.2 0.0013 19.0 3.2 6.5 4 3 2 6 6 6 1 ABC transporter C-terminal domain PSII_Pbs27 PF13326.6 EEQ40838.1 - 0.02 15.2 2.0 0.02 15.2 2.0 3.0 2 1 0 2 2 2 0 Photosystem II Pbs27 Leucyl-specific PF14795.6 EEQ40838.1 - 1.8 8.7 4.0 0.71 10.0 0.6 2.2 2 0 0 2 2 2 0 Leucine-tRNA synthetase-specific domain DUF730 PF05325.11 EEQ40838.1 - 1.9 8.6 4.6 0.97 9.5 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Rer1 PF03248.13 EEQ40839.1 - 8.7e-78 259.9 3.7 9.8e-78 259.8 3.7 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.9 EEQ40839.1 - 0.0056 16.3 3.7 0.0056 16.3 3.7 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2208) DUF4131 PF13567.6 EEQ40839.1 - 0.48 10.1 5.7 4.2 7.0 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ThrE PF06738.12 EEQ40839.1 - 1.3 8.4 5.0 1.1 8.5 0.1 2.0 1 1 1 2 2 2 0 Putative threonine/serine exporter Fib_alpha PF08702.10 EEQ40841.1 - 0.0005 20.3 0.8 0.0011 19.1 0.8 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EEQ40841.1 - 0.027 14.5 4.5 0.05 13.6 4.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF16 PF01519.16 EEQ40841.1 - 0.13 12.7 0.7 0.33 11.5 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF16 FAM76 PF16046.5 EEQ40841.1 - 0.79 9.0 7.7 1.4 8.2 7.7 1.4 1 0 0 1 1 1 0 FAM76 protein SMYLE_N PF18615.1 EEQ40841.1 - 1.3 8.5 5.3 2 7.9 5.3 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Fungal_TACC PF12709.7 EEQ40842.1 - 3.9e-22 78.5 15.9 3.9e-22 78.5 15.9 5.3 2 1 4 6 6 6 1 Fungal Transforming acidic coiled-coil (TACC) proteins ATG16 PF08614.11 EEQ40842.1 - 0.0019 18.5 20.3 0.0094 16.2 7.7 3.5 1 1 2 3 3 2 2 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 EEQ40842.1 - 0.0062 17.1 14.8 0.0062 17.1 14.8 3.3 1 1 2 3 3 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Lant_dehydr_C PF14028.6 EEQ40842.1 - 0.0079 15.8 2.4 0.0079 15.8 2.4 2.4 1 1 2 3 3 3 1 Lantibiotic biosynthesis dehydratase C-term Syntaxin-18_N PF10496.9 EEQ40842.1 - 0.02 15.1 3.8 0.02 15.1 3.8 3.1 1 1 0 2 2 1 0 SNARE-complex protein Syntaxin-18 N-terminus WD40_alt PF14077.6 EEQ40842.1 - 0.021 14.7 0.0 0.021 14.7 0.0 3.5 3 2 0 3 3 3 0 Alternative WD40 repeat motif TMF_DNA_bd PF12329.8 EEQ40842.1 - 0.025 14.6 11.7 0.025 14.6 11.7 4.9 1 1 2 4 4 3 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.12 EEQ40842.1 - 0.13 10.8 7.1 0.081 11.4 0.4 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Filament PF00038.21 EEQ40842.1 - 0.16 11.5 40.6 0.25 10.9 40.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein Fez1 PF06818.15 EEQ40842.1 - 0.44 11.0 46.3 0.34 11.3 31.6 2.6 1 1 1 2 2 2 0 Fez1 Spc7 PF08317.11 EEQ40842.1 - 0.53 9.1 49.5 1.4 7.7 27.1 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein FAM76 PF16046.5 EEQ40842.1 - 1.1 8.5 43.9 0.13 11.6 14.0 3.4 1 1 2 3 3 3 0 FAM76 protein DUF3584 PF12128.8 EEQ40842.1 - 1.2 6.5 39.8 1.8 6.0 39.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Sec34 PF04136.15 EEQ40842.1 - 1.3 8.9 38.1 0.1 12.5 4.3 4.7 2 1 3 5 5 5 0 Sec34-like family kleA_kleC PF17383.2 EEQ40842.1 - 1.7 9.0 12.2 1.8 8.9 0.1 3.7 2 1 2 4 4 4 0 Uncharacterized KorC regulated protein A Atg14 PF10186.9 EEQ40842.1 - 2 7.4 44.9 1.4 8.0 15.1 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 EEQ40842.1 - 2.1 7.6 31.7 9 5.6 15.7 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 EEQ40842.1 - 2.1 8.4 47.9 1.1 9.4 12.5 4.4 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding Viral_env_E26 PF11050.8 EEQ40842.1 - 2.2 7.6 9.2 0.29 10.5 2.6 2.3 1 1 1 2 2 2 0 Virus envelope protein E26 KASH_CCD PF14662.6 EEQ40842.1 - 2.5 7.9 49.4 0.045 13.6 33.2 3.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH KfrA_N PF11740.8 EEQ40842.1 - 2.5 8.8 17.6 0.076 13.7 6.1 3.2 1 1 2 3 3 3 0 Plasmid replication region DNA-binding N-term ZapB PF06005.12 EEQ40842.1 - 4.4 7.8 47.1 2.7 8.5 9.8 4.6 3 1 0 4 4 4 0 Cell division protein ZapB Mod_r PF07200.13 EEQ40842.1 - 6.1 6.9 48.9 2.1 8.4 19.4 3.3 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HMMR_N PF15905.5 EEQ40842.1 - 6.1 6.2 53.7 4 6.8 49.9 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal UPF0242 PF06785.11 EEQ40842.1 - 6.3 6.8 54.1 22 5.1 30.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 EEQ40842.1 - 6.9 6.7 31.9 5.3 7.1 9.0 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EEQ40842.1 - 9.5 6.4 40.6 26 5.0 20.6 3.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Beta_elim_lyase PF01212.21 EEQ40843.1 - 1.2e-77 261.1 0.0 1.4e-77 260.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EEQ40843.1 - 2.4e-05 23.7 0.0 4.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 EEQ40843.1 - 0.077 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 EEQ40843.1 - 0.13 10.8 0.0 0.45 9.0 0.0 1.8 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme TFIIA PF03153.13 EEQ40844.1 - 1.6e-53 183.2 26.2 2e-29 103.9 22.4 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DNA_pol_phi PF04931.13 EEQ40844.1 - 3.1 5.8 13.6 4.3 5.3 13.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi RhoGAP PF00620.27 EEQ40845.1 - 1.3e-32 112.7 0.4 5.4e-32 110.7 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.29 EEQ40845.1 - 5.4e-11 42.9 0.0 1.5e-10 41.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PX PF00787.24 EEQ40845.1 - 6.4e-08 32.6 0.0 2.1e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 PX domain PH_11 PF15413.6 EEQ40845.1 - 0.0018 18.7 0.0 0.0082 16.6 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain Hist_deacetyl PF00850.19 EEQ40846.1 - 1.5e-50 172.4 0.0 3.7e-49 167.9 0.0 2.2 1 1 0 1 1 1 1 Histone deacetylase domain SF3A3 PF16837.5 EEQ40846.1 - 1.2 9.7 6.1 3.2 8.3 4.7 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 LIAS_N PF16881.5 EEQ40847.1 - 1.4e-19 70.5 0.1 3.3e-19 69.3 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EEQ40847.1 - 1e-10 42.3 0.0 2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Methyltransf_24 PF13578.6 EEQ40847.1 - 0.16 13.0 0.0 0.35 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NUDIX PF00293.28 EEQ40848.1 - 7.9e-19 68.0 0.0 1.5e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain Pox_A_type_inc PF04508.12 EEQ40849.1 - 0.35 10.8 0.1 0.35 10.8 0.1 4.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Methyltrn_RNA_3 PF02598.17 EEQ40850.1 - 8.5e-68 228.9 1.9 1e-67 228.7 1.9 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase DUF4108 PF13390.6 EEQ40850.1 - 0.011 15.6 0.4 0.011 15.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) PRONE PF03759.13 EEQ40850.1 - 0.023 13.5 0.5 0.035 12.9 0.5 1.3 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) RNB PF00773.19 EEQ40850.1 - 1.6 8.0 5.4 2 7.7 4.9 1.3 1 1 0 1 1 1 0 RNB domain Glyco_hydro_17 PF00332.18 EEQ40851.1 - 2.1e-70 237.8 2.0 2.3e-70 237.7 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 VWA_2 PF13519.6 EEQ40851.1 - 0.15 12.7 0.0 1 10.0 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Glyco_hydro_16 PF00722.21 EEQ40852.1 - 1.3e-42 145.2 1.1 1.3e-42 145.2 1.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 FAM196 PF15265.6 EEQ40852.1 - 7.7 5.9 30.6 11 5.4 30.6 1.1 1 0 0 1 1 1 0 FAM196 family SPRY PF00622.28 EEQ40853.1 - 4.2e-12 46.3 0.0 7.5e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 SPRY domain TMEM132D_C PF15706.5 EEQ40853.1 - 0.093 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term EphA2_TM PF14575.6 EEQ40853.1 - 0.1 13.5 0.0 0.28 12.1 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain NID PF07292.13 EEQ40855.1 - 0.11 13.1 0.7 0.34 11.6 0.1 2.1 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) DUF3445 PF11927.8 EEQ40856.1 - 4.3e-61 206.4 0.0 5.1e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) SH3_1 PF00018.28 EEQ40857.1 - 2e-25 88.2 7.5 3.4e-13 49.0 0.9 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EEQ40857.1 - 4.3e-24 84.1 4.4 2.5e-13 49.6 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.20 EEQ40857.1 - 3.3e-21 75.3 0.0 8.8e-21 73.9 0.0 1.8 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 EEQ40857.1 - 2.4e-14 52.7 0.9 1.9e-06 27.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain DMRT-like PF15791.5 EEQ40858.1 - 6.8 7.1 9.1 27 5.2 6.6 2.2 1 1 1 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 Rab5ip PF07019.12 EEQ40859.1 - 1.6e-23 83.1 0.6 1.8e-23 82.9 0.6 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF5084 PF16894.5 EEQ40859.1 - 0.019 15.4 0.1 0.022 15.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5084) zf-UBR PF02207.20 EEQ40860.1 - 3.5e-16 59.1 11.4 3.5e-16 59.1 11.4 2.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.6 EEQ40860.1 - 0.021 15.1 1.0 0.021 15.1 1.0 4.5 4 0 0 4 4 4 0 Ring finger domain zf-CXXC PF02008.20 EEQ40860.1 - 0.16 12.0 2.5 0.69 10.0 2.5 2.2 1 0 0 1 1 1 0 CXXC zinc finger domain zf-C3HC4 PF00097.25 EEQ40860.1 - 9.8 6.2 11.1 0.22 11.4 1.3 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-UBR PF02207.20 EEQ40861.1 - 9.1e-16 57.8 10.6 9.1e-16 57.8 10.6 2.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EEQ40861.1 - 1.2e-05 25.0 0.0 3.2e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-C3HC4 PF00097.25 EEQ40861.1 - 0.0015 18.4 1.4 0.0071 16.2 1.4 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2113 PF09886.9 EEQ40861.1 - 0.11 11.8 0.6 0.29 10.4 0.6 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2113) zf-RING_2 PF13639.6 EEQ40861.1 - 7.6 7.0 19.3 0.021 15.1 2.6 3.6 3 0 0 3 3 3 0 Ring finger domain tRNA-synt_1b PF00579.25 EEQ40862.1 - 3.6e-74 249.7 0.0 4.6e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Epimerase PF01370.21 EEQ40863.1 - 5.6e-14 52.2 0.0 8.7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EEQ40863.1 - 5.6e-11 42.0 0.0 7.8e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EEQ40863.1 - 6e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EEQ40863.1 - 8.1e-06 25.2 0.1 0.058 12.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EEQ40863.1 - 4.3e-05 23.1 0.0 7.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EEQ40863.1 - 0.00021 20.9 0.2 0.067 12.7 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.25 EEQ40863.1 - 0.0018 17.7 0.2 0.0041 16.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Dynamitin PF04912.14 EEQ40864.1 - 8.2e-05 22.1 2.0 8.2e-05 22.1 2.0 2.0 2 0 0 2 2 2 1 Dynamitin Med9 PF07544.13 EEQ40864.1 - 0.0011 19.1 4.8 0.015 15.4 1.3 2.8 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 SKA2 PF16740.5 EEQ40864.1 - 0.0021 17.8 1.8 0.46 10.3 0.2 2.6 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 BLOC1_2 PF10046.9 EEQ40864.1 - 0.0031 17.8 10.5 0.0034 17.7 0.9 3.5 4 0 0 4 4 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 EEQ40864.1 - 0.024 15.1 0.1 0.024 15.1 0.1 3.6 2 2 1 3 3 3 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 EEQ40864.1 - 0.061 13.4 6.6 0.5 10.4 0.2 3.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 EEQ40864.1 - 0.067 13.0 5.0 0.12 12.2 0.2 3.4 2 1 2 4 4 4 0 DASH complex subunit Dam1 NPV_P10 PF05531.12 EEQ40864.1 - 0.072 13.6 8.1 0.56 10.7 0.2 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 EEQ40864.1 - 0.11 12.6 7.5 7.6 6.7 0.4 3.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Prefoldin PF02996.17 EEQ40864.1 - 0.12 12.3 1.2 1.1 9.2 1.2 2.6 1 1 0 1 1 1 0 Prefoldin subunit COG2 PF06148.11 EEQ40864.1 - 0.22 11.6 5.6 0.075 13.1 2.0 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 THP2 PF09432.10 EEQ40864.1 - 0.23 11.5 6.0 0.14 12.2 1.1 2.6 2 0 0 2 2 2 0 Tho complex subunit THP2 TMF_TATA_bd PF12325.8 EEQ40864.1 - 0.47 10.7 6.6 0.15 12.2 2.0 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 EEQ40864.1 - 0.74 9.9 4.2 0.88 9.6 0.4 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) ZapB PF06005.12 EEQ40864.1 - 0.76 10.3 6.4 27 5.3 1.9 3.5 2 1 0 2 2 2 0 Cell division protein ZapB Cytochrom_B562 PF07361.11 EEQ40864.1 - 0.85 10.3 8.0 2.3 8.9 0.6 3.6 3 1 0 3 3 3 0 Cytochrome b562 Laminin_II PF06009.12 EEQ40864.1 - 1 9.4 9.1 0.067 13.2 2.6 2.3 2 1 0 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.6 EEQ40864.1 - 3.7 8.0 7.8 15 6.1 0.1 3.4 2 1 0 3 3 3 0 Snapin/Pallidin Atg14 PF10186.9 EEQ40864.1 - 4.9 6.1 7.6 0.4 9.7 1.2 2.4 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EEQ40864.1 - 5.9 6.4 11.7 0.045 13.3 0.9 2.3 3 0 0 3 3 2 0 Exonuclease VII, large subunit DUF4164 PF13747.6 EEQ40864.1 - 6.6 7.1 9.5 7.8 6.9 0.7 2.9 2 1 1 3 3 2 0 Domain of unknown function (DUF4164) PIG-F PF06699.11 EEQ40865.1 - 1.3e-50 172.0 6.4 1.6e-50 171.8 6.4 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F ECF_trnsprt PF12822.7 EEQ40865.1 - 0.43 10.7 11.5 0.066 13.3 0.8 2.8 1 1 1 2 2 2 0 ECF transporter, substrate-specific component DUF373 PF04123.13 EEQ40865.1 - 0.81 9.1 3.4 9.3 5.6 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) CPSF_A PF03178.15 EEQ40866.1 - 2e-92 310.0 0.0 8.2e-92 307.9 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EEQ40866.1 - 1.5e-21 76.6 4.2 1.5e-21 76.6 4.2 2.2 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term FG-GAP_2 PF14312.6 EEQ40867.1 - 0.031 14.5 15.4 0.79 10.0 2.2 3.9 3 0 0 3 3 3 0 FG-GAP repeat Flocculin_t3 PF13928.6 EEQ40868.1 - 3.7e-37 126.6 99.9 7.1e-17 61.6 27.3 6.8 6 2 1 7 7 7 4 Flocculin type 3 repeat DEC-1_N PF04625.13 EEQ40868.1 - 0.00057 19.0 8.5 0.00057 19.0 8.5 2.1 2 0 0 2 2 2 1 DEC-1 protein, N-terminal region DUF3347 PF11827.8 EEQ40868.1 - 0.025 14.8 7.4 0.017 15.3 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Antimicrobial25 PF16839.5 EEQ40868.1 - 2.4 8.3 10.4 4.9 7.3 0.3 3.6 3 0 0 3 3 3 0 Nematode antimicrobial peptide Thioredoxin PF00085.20 EEQ40869.1 - 1e-16 60.8 0.0 5.9e-14 51.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EEQ40869.1 - 7.3e-11 42.5 0.4 6.3e-07 29.8 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EEQ40869.1 - 3.1e-09 36.6 2.2 4.7e-08 32.7 0.2 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EEQ40869.1 - 1.7e-08 34.7 1.7 0.0032 17.8 0.1 3.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.6 EEQ40869.1 - 4.5e-08 33.2 2.9 1.2e-07 31.9 2.8 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 EEQ40869.1 - 1.8e-06 27.9 0.1 5.4e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_7 PF13899.6 EEQ40869.1 - 9.3e-05 22.5 0.4 0.001 19.2 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.6 EEQ40869.1 - 0.015 15.0 0.0 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin HyaE PF07449.11 EEQ40869.1 - 0.025 14.5 0.2 0.3 11.1 0.0 2.5 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EEQ40869.1 - 0.048 13.6 0.3 0.38 10.7 0.1 2.3 1 1 0 2 2 2 0 AhpC/TSA family Thioredoxin_3 PF13192.6 EEQ40869.1 - 0.18 11.8 0.0 9.4 6.4 0.0 2.7 2 1 1 3 3 3 0 Thioredoxin domain ER_lumen_recept PF00810.18 EEQ40870.1 - 9.8e-52 175.7 11.8 9.8e-52 175.7 11.8 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EEQ40870.1 - 5.2e-05 22.9 7.4 0.026 14.3 0.3 3.8 3 1 1 4 4 4 2 PQ loop repeat HlyIII PF03006.20 EEQ40870.1 - 0.51 10.0 13.1 0.67 9.6 13.1 1.3 1 0 0 1 1 1 0 Haemolysin-III related Proteasome PF00227.26 EEQ40872.1 - 9.6e-38 129.6 0.1 7.2e-37 126.7 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit zf-Tim10_DDP PF02953.15 EEQ40873.1 - 5.3e-22 77.2 1.8 6.7e-22 76.9 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3398 PF11878.8 EEQ40873.1 - 0.0084 16.5 0.7 0.011 16.2 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) Vicilin_N PF04702.12 EEQ40873.1 - 0.017 14.9 2.3 0.019 14.8 2.3 1.1 1 0 0 1 1 1 0 Vicilin N terminal region DUF676 PF05057.14 EEQ40874.1 - 1.2e-36 126.3 0.0 2e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EEQ40874.1 - 0.00019 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DLH PF01738.18 EEQ40874.1 - 0.0021 17.6 0.0 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family PGAP1 PF07819.13 EEQ40874.1 - 0.0038 17.0 0.0 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 EEQ40874.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EEQ40874.1 - 0.55 9.8 2.0 1.1 8.8 0.4 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold DUF4637 PF15470.6 EEQ40874.1 - 2 8.1 7.3 4.4 7.0 7.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) ABC1 PF03109.16 EEQ40875.1 - 4.4e-24 84.9 0.2 5.7e-15 55.5 0.0 2.9 2 0 0 2 2 2 2 ABC1 family RIO1 PF01163.22 EEQ40875.1 - 0.0015 18.2 0.5 0.0087 15.7 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.25 EEQ40875.1 - 0.07 12.5 0.3 0.8 9.0 0.3 2.7 2 1 0 2 2 2 0 Protein kinase domain DLH PF01738.18 EEQ40876.1 - 2.2e-35 122.2 0.0 2.5e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EEQ40876.1 - 0.046 13.0 0.0 7.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 BAAT_C PF08840.11 EEQ40876.1 - 0.079 12.9 0.1 0.37 10.7 0.1 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peripla_BP_6 PF13458.6 EEQ40876.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein Abhydrolase_1 PF00561.20 EEQ40876.1 - 0.13 11.9 0.0 16 5.0 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 EEQ40877.1 - 3e-35 121.7 0.0 3.4e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EEQ40877.1 - 0.0047 16.8 0.0 0.0068 16.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase COS PF18568.1 EEQ40877.1 - 0.041 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 TRIM C-terminal subgroup One Signature domain Methyltransf_11 PF08241.12 EEQ40878.1 - 9.5e-25 87.1 0.0 2.2e-24 85.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ40878.1 - 4.1e-24 85.1 0.0 5.9e-23 81.4 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ40878.1 - 4.6e-21 75.4 0.0 9.6e-18 64.6 0.0 2.1 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ40878.1 - 3.9e-19 69.1 0.0 8e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ40878.1 - 8.1e-14 52.2 0.0 2.1e-12 47.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ40878.1 - 1.8e-11 43.8 0.0 3.3e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 EEQ40878.1 - 2.4e-08 33.3 0.0 2.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 EEQ40878.1 - 1.9e-07 30.8 0.0 4e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.12 EEQ40878.1 - 1e-05 24.8 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.20 EEQ40878.1 - 0.00045 19.4 0.0 0.0007 18.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EEQ40878.1 - 0.0016 18.3 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_29 PF03141.16 EEQ40878.1 - 0.0019 16.8 0.0 0.0027 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 EEQ40878.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 EEQ40878.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.20 EEQ40878.1 - 0.048 13.0 0.0 0.076 12.3 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EEQ40878.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 EEQ40879.1 - 4.8e-11 42.7 0.5 4.8e-11 42.7 0.5 2.0 2 1 0 2 2 2 1 Eukaryotic aspartyl protease FYDLN_acid PF09538.10 EEQ40879.1 - 0.059 14.1 3.5 0.13 13.0 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Asp PF00026.23 EEQ40880.1 - 0.00022 20.7 0.4 0.00022 20.7 0.4 2.4 2 1 0 2 2 2 1 Eukaryotic aspartyl protease DUF5514 PF17633.2 EEQ40881.1 - 0.11 12.7 0.1 0.22 11.8 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5514) Peptidase_M20 PF01546.28 EEQ40882.1 - 1.6e-26 93.3 0.0 2.6e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ40882.1 - 8.9e-11 41.7 0.0 1.6e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ40882.1 - 0.00019 21.2 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 DUF383 PF04063.14 EEQ40883.1 - 6.3e-70 234.7 0.5 7.3e-69 231.3 0.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EEQ40883.1 - 9e-23 79.9 1.3 2.4e-22 78.5 1.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Peptidase_C50 PF03568.17 EEQ40883.1 - 0.083 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C50 TFIIF_alpha PF05793.12 EEQ40884.1 - 9.2e-11 41.0 2.1 9.2e-11 41.0 2.1 3.4 2 2 1 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vac7 PF12751.7 EEQ40884.1 - 0.017 14.6 1.0 0.042 13.3 1.0 1.7 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Mito_carr PF00153.27 EEQ40885.1 - 7.2e-51 170.1 0.5 1.2e-19 70.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF5572 PF17733.1 EEQ40888.1 - 3.1e-24 84.5 0.4 5.7e-24 83.7 0.4 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Mannosyl_trans PF05007.13 EEQ40889.1 - 3.1e-72 243.6 24.6 5.2e-72 242.8 24.6 1.4 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EEQ40889.1 - 1.4e-09 37.6 6.7 1.4e-09 37.6 6.7 2.2 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U DUF3910 PF13049.6 EEQ40890.1 - 0.014 15.7 1.4 0.039 14.3 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3910) DUF1664 PF07889.12 EEQ40890.1 - 0.84 9.7 7.6 0.83 9.7 6.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) RNase_PH PF01138.21 EEQ40891.1 - 2e-34 118.9 0.2 2.8e-34 118.5 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EEQ40891.1 - 1.3e-05 25.1 0.2 2.4e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF2000 PF09391.10 EEQ40891.1 - 0.092 12.7 0.1 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2000) SURF4 PF02077.15 EEQ40892.1 - 6.1e-90 301.4 14.3 7e-90 301.2 14.3 1.0 1 0 0 1 1 1 1 SURF4 family MerC PF03203.14 EEQ40892.1 - 1.4 9.4 17.4 1.6 9.2 6.1 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein DUF373 PF04123.13 EEQ40892.1 - 7.9 5.8 12.6 5.5 6.3 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Cyto_heme_lyase PF01265.17 EEQ40893.1 - 3.4e-41 141.8 7.2 1.1e-40 140.1 7.2 1.7 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase RMF PF04957.12 EEQ40893.1 - 0.094 12.9 2.0 23 5.3 0.1 3.3 3 0 0 3 3 3 0 Ribosome modulation factor Kelch_4 PF13418.6 EEQ40894.1 - 0.0003 20.7 0.1 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_3 PF13415.6 EEQ40894.1 - 0.0055 17.0 0.1 0.068 13.5 0.0 2.9 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EEQ40894.1 - 0.043 14.1 0.1 0.65 10.4 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Kelch_1 PF01344.25 EEQ40894.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 Kelch motif Kelch_5 PF13854.6 EEQ40894.1 - 0.65 10.0 2.4 4.6 7.3 0.0 3.4 4 0 0 4 4 4 0 Kelch motif GHMP_kinases_N PF00288.26 EEQ40896.1 - 4.6e-15 55.6 2.9 1.1e-14 54.4 1.5 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEQ40896.1 - 2.4e-08 34.2 0.1 5.7e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PDH PF02153.17 EEQ40897.1 - 2.5e-14 52.9 0.0 3.5e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EEQ40897.1 - 2.8e-07 30.8 0.0 4.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EEQ40897.1 - 8.4e-07 29.5 0.0 1.8e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EEQ40897.1 - 0.00037 19.9 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EEQ40897.1 - 0.0022 17.9 0.1 0.0036 17.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EEQ40897.1 - 0.017 14.7 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Rossmann-like PF10727.9 EEQ40897.1 - 0.041 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain Arf PF00025.21 EEQ40899.1 - 4.5e-75 250.9 0.1 5.1e-75 250.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EEQ40899.1 - 6.7e-16 58.6 0.0 8.9e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EEQ40899.1 - 8.1e-11 41.7 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EEQ40899.1 - 4.3e-10 39.4 0.0 4.9e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EEQ40899.1 - 4.8e-10 39.1 0.4 8.1e-06 25.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EEQ40899.1 - 2.3e-09 36.9 0.0 2.9e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EEQ40899.1 - 0.00011 22.3 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EEQ40899.1 - 0.00018 20.6 0.9 0.003 16.6 0.2 2.1 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EEQ40899.1 - 0.0026 18.3 0.3 0.0099 16.4 0.3 1.8 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EEQ40899.1 - 0.048 14.2 0.1 0.086 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EEQ40899.1 - 0.24 11.0 0.8 8.7 5.9 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IPP-2 PF04979.14 EEQ40900.1 - 9.9e-20 71.6 11.7 9.9e-20 71.6 11.7 1.9 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Fimbrillin_C PF15495.6 EEQ40900.1 - 0.07 13.6 0.6 0.17 12.3 0.1 2.0 2 1 0 2 2 2 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal LPD11 PF18824.1 EEQ40900.1 - 0.16 12.1 3.4 1.1 9.4 0.3 2.2 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 11 RAC_head PF16717.5 EEQ40902.1 - 1.6e-20 73.9 8.1 1.6e-20 73.9 8.1 3.6 2 1 1 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 EEQ40902.1 - 6.3e-16 58.2 0.1 2e-15 56.6 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain Spore_Cse60 PF10957.8 EEQ40902.1 - 0.039 14.0 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 Sporulation protein Cse60 SBDS PF01172.18 EEQ40903.1 - 7.8e-35 118.8 0.6 1.3e-34 118.1 0.6 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EEQ40903.1 - 9.3e-30 103.0 0.6 9.3e-30 103.0 0.6 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain GTP_cyclohydro2 PF00925.20 EEQ40903.1 - 0.085 12.5 0.2 0.22 11.1 0.2 1.8 2 1 0 2 2 2 0 GTP cyclohydrolase II Glyco_hydro_38N PF01074.22 EEQ40904.1 - 1e-76 258.1 0.1 1.5e-76 257.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EEQ40904.1 - 1.5e-25 89.1 0.0 4.4e-25 87.7 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 EEQ40904.1 - 4e-19 69.5 0.0 7.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain GUN4 PF05419.12 EEQ40904.1 - 0.15 12.1 5.2 5.2 7.2 1.0 3.2 3 0 0 3 3 3 0 GUN4-like Glyco_hydro_75 PF07335.11 EEQ40905.1 - 0.14 12.4 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 Ribonuclease_T2 PF00445.18 EEQ40906.1 - 1.5e-34 119.8 0.4 2.4e-34 119.2 0.4 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family PYRIN PF02758.16 EEQ40906.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain MaoC_dehydratas PF01575.19 EEQ40907.1 - 1.3e-05 24.8 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EEQ40907.1 - 0.035 14.3 0.0 3.2 7.9 0.0 2.6 2 1 1 3 3 3 0 N-terminal half of MaoC dehydratase GAPES1 PF17155.4 EEQ40907.1 - 0.076 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain BSD PF03909.17 EEQ40908.1 - 1.8e-23 82.3 0.8 6.7e-15 54.8 0.0 3.4 4 0 0 4 4 4 2 BSD domain PH_TFIIH PF08567.11 EEQ40908.1 - 4.4e-15 55.8 3.5 4.8e-14 52.4 0.6 2.7 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Brix PF04427.18 EEQ40909.1 - 1.6e-27 96.9 0.4 2.3e-27 96.4 0.4 1.2 1 0 0 1 1 1 1 Brix domain ATP-synt_B PF00430.18 EEQ40909.1 - 0.96 9.5 10.2 1.5 9.0 10.2 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1764 PF08576.10 EEQ40909.1 - 8.1 7.4 6.8 17 6.3 6.8 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Xpo1 PF08389.12 EEQ40910.1 - 1e-05 25.6 6.0 0.00075 19.6 0.8 4.4 4 0 0 4 4 4 2 Exportin 1-like protein IBN_N PF03810.19 EEQ40910.1 - 0.089 12.7 0.3 4.8 7.2 0.0 3.4 3 0 0 3 3 3 0 Importin-beta N-terminal domain Methyltransf_23 PF13489.6 EEQ40911.1 - 0.0017 18.2 0.0 0.011 15.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EEQ40911.1 - 0.0026 17.5 0.0 0.085 12.6 0.0 2.2 2 0 0 2 2 2 1 Lysine methyltransferase 6PF2K PF01591.18 EEQ40912.1 - 2.4e-73 246.1 0.0 3e-72 242.6 0.0 2.4 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EEQ40912.1 - 7.6e-32 110.6 2.9 1.5e-24 86.8 0.0 3.4 3 0 0 3 3 3 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EEQ40912.1 - 0.021 15.0 0.1 0.91 9.7 0.0 3.1 2 1 0 2 2 2 0 AAA domain KTI12 PF08433.10 EEQ40912.1 - 0.057 12.9 0.2 0.21 11.0 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Dicty_REP PF05086.12 EEQ40912.1 - 2.4 6.0 3.7 3.5 5.5 3.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Vac7 PF12751.7 EEQ40913.1 - 6.3e-23 81.8 28.0 3.2e-18 66.4 0.0 4.7 3 2 0 4 4 4 3 Vacuolar segregation subunit 7 PHO4 PF01384.20 EEQ40914.1 - 7.5 5.5 7.3 10 5.1 7.3 1.3 1 0 0 1 1 1 0 Phosphate transporter family DUF1652 PF07865.11 EEQ40916.1 - 0.1 12.4 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) p450 PF00067.22 EEQ40918.1 - 1e-44 153.1 0.0 3.3e-40 138.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Fungal_trans_2 PF11951.8 EEQ40919.1 - 1.6e-44 152.3 0.1 2.2e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ40919.1 - 4.1e-06 26.8 9.4 8.7e-06 25.8 9.4 1.5 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Collagen PF01391.18 EEQ40919.1 - 0.054 13.3 1.9 0.1 12.4 1.9 1.3 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Sporozoite_P67 PF05642.11 EEQ40919.1 - 0.99 7.4 8.3 1.3 7.0 8.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DRIM PF07539.12 EEQ40920.1 - 0.061 11.6 0.0 0.087 11.1 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis Pyr_redox_2 PF07992.14 EEQ40921.1 - 8.6e-11 41.6 0.0 5.9e-07 29.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ40921.1 - 0.00037 19.8 0.6 2.8 7.1 0.7 3.9 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EEQ40921.1 - 0.0004 19.6 0.0 1.5 7.9 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 EEQ40921.1 - 0.0018 18.8 0.4 1.1 9.9 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ40921.1 - 0.0087 15.2 0.2 0.36 9.8 0.3 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EEQ40921.1 - 0.0093 16.2 0.9 0.79 10.0 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DUF1412 PF07203.11 EEQ40921.1 - 0.035 14.3 0.0 0.098 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1412) DAO PF01266.24 EEQ40921.1 - 0.036 13.6 3.7 1.5 8.3 0.7 3.2 2 2 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EEQ40921.1 - 0.04 13.8 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EEQ40921.1 - 0.053 12.8 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EEQ40921.1 - 0.057 12.7 2.9 2.1 7.5 0.2 2.7 3 0 0 3 3 3 0 FAD binding domain GMC_oxred_N PF00732.19 EEQ40921.1 - 0.077 12.4 0.0 0.22 10.9 0.0 1.8 1 0 0 1 1 1 0 GMC oxidoreductase NAD_binding_9 PF13454.6 EEQ40921.1 - 0.1 12.6 10.1 0.67 9.9 0.9 4.2 3 1 2 5 5 5 0 FAD-NAD(P)-binding Dak1 PF02733.17 EEQ40922.1 - 1.3e-98 329.8 0.7 1.7e-98 329.4 0.7 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EEQ40922.1 - 2.4e-50 170.8 1.2 2.4e-50 170.8 1.2 1.9 2 0 0 2 2 2 1 DAK2 domain Fungal_trans_2 PF11951.8 EEQ40923.1 - 1.6e-92 310.3 0.9 2.2e-92 309.8 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ40923.1 - 1.1e-08 35.0 10.1 1.7e-08 34.4 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLN_propep PF16485.5 EEQ40923.1 - 0.0075 16.0 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 Protealysin propeptide Flocculin_t3 PF13928.6 EEQ40924.1 - 1.7e-12 47.6 22.0 1.7e-12 47.6 22.0 2.9 2 1 1 3 3 3 1 Flocculin type 3 repeat ERO1 PF04137.15 EEQ40925.1 - 2.7e-118 395.2 0.1 3.8e-118 394.7 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DEAD PF00270.29 EEQ40926.1 - 2.6e-52 177.1 0.0 5.3e-52 176.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EEQ40926.1 - 3.5e-36 123.9 0.1 1.8e-31 108.8 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain CMS1 PF14617.6 EEQ40926.1 - 0.004 16.5 0.0 0.004 16.5 0.0 3.3 2 1 1 3 3 2 1 U3-containing 90S pre-ribosomal complex subunit Peptidase_S64 PF08192.11 EEQ40926.1 - 0.019 13.5 8.9 0.018 13.5 7.4 1.6 2 0 0 2 2 2 0 Peptidase family S64 AAA_22 PF13401.6 EEQ40926.1 - 0.021 15.1 0.1 0.1 12.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain DDHD PF02862.17 EEQ40926.1 - 0.029 14.6 4.7 0.048 13.8 4.7 1.5 1 0 0 1 1 1 0 DDHD domain UTP25 PF06862.12 EEQ40926.1 - 0.037 12.8 0.0 0.037 12.8 0.0 3.7 3 1 1 4 4 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 MDM1 PF15501.6 EEQ40926.1 - 0.097 11.8 20.1 0.11 11.7 19.3 1.4 2 0 0 2 2 2 0 Nuclear protein MDM1 Tim54 PF11711.8 EEQ40926.1 - 0.11 11.3 17.3 0.18 10.6 17.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 EEQ40926.1 - 0.23 10.6 9.6 0.33 10.1 9.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RPOL_N PF14700.6 EEQ40926.1 - 0.8 9.0 14.5 1.4 8.3 14.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal NPR3 PF03666.13 EEQ40926.1 - 2.4 6.9 22.8 3.6 6.3 22.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cellulose_synt PF03552.14 EEQ40926.1 - 5.6 5.3 9.0 7.5 4.9 9.0 1.1 1 0 0 1 1 1 0 Cellulose synthase AAA_15 PF13175.6 EEQ40926.1 - 5.9 6.5 25.0 19 4.8 23.4 2.1 2 0 0 2 2 2 0 AAA ATPase domain AA_permease PF00324.21 EEQ40927.1 - 2e-117 392.7 37.1 2.4e-117 392.5 37.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ40927.1 - 1.9e-37 129.1 39.4 2.4e-37 128.8 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease UEV PF05743.13 EEQ40928.1 - 1.1e-25 89.8 0.0 2e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EEQ40928.1 - 8.3e-14 51.3 0.1 2.5e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 Vps23 core domain TPR_MLP1_2 PF07926.12 EEQ40928.1 - 0.022 14.8 0.4 0.041 13.9 0.4 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HalX PF08663.10 EEQ40928.1 - 0.035 14.4 0.0 0.084 13.2 0.0 1.6 1 0 0 1 1 1 0 HalX domain Syntaxin_2 PF14523.6 EEQ40928.1 - 0.1 13.0 1.2 0.16 12.4 0.4 1.8 2 0 0 2 2 2 0 Syntaxin-like protein Laminin_II PF06009.12 EEQ40928.1 - 0.11 12.4 1.9 0.23 11.5 0.6 2.0 2 0 0 2 2 2 0 Laminin Domain II FUSC-like PF12805.7 EEQ40928.1 - 0.28 10.2 0.8 0.45 9.5 0.8 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DKCLD PF08068.12 EEQ40929.1 - 2.1e-32 111.0 0.2 1.6e-31 108.1 0.3 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EEQ40929.1 - 2.6e-23 81.9 0.5 5.5e-23 80.9 0.5 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EEQ40929.1 - 1.5e-20 74.1 7.3 1e-19 71.4 0.0 3.7 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EEQ40929.1 - 2.3e-20 72.3 0.8 5.1e-20 71.2 0.8 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EEQ40929.1 - 0.0053 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain CENP-N PF05238.13 EEQ40929.1 - 0.053 12.8 9.7 0.08 12.2 9.7 1.2 1 0 0 1 1 1 0 Kinetochore protein CHL4 like RR_TM4-6 PF06459.12 EEQ40929.1 - 2.5 7.9 32.6 3.5 7.4 32.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Cohesin_load PF10345.9 EEQ40931.1 - 1.7e-78 264.6 2.1 2.1e-78 264.3 2.1 1.0 1 0 0 1 1 1 1 Cohesin loading factor TPR_8 PF13181.6 EEQ40931.1 - 0.0006 19.8 0.3 12 6.4 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat DivIC PF04977.15 EEQ40932.1 - 0.059 13.1 6.9 1.7 8.5 1.0 3.9 3 1 1 4 4 4 0 Septum formation initiator bZIP_2 PF07716.15 EEQ40932.1 - 0.57 10.3 12.6 3.5 7.8 0.3 4.2 4 0 0 4 4 4 0 Basic region leucine zipper Cnn_1N PF07989.11 EEQ40932.1 - 3.8 7.7 11.4 4.9 7.4 0.4 4.1 2 2 1 3 3 3 0 Centrosomin N-terminal motif 1 Exo_endo_phos PF03372.23 EEQ40935.1 - 0.0019 17.7 0.0 0.0023 17.5 0.0 1.3 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EEQ40936.1 - 6.7e-06 26.1 5.3 2.2e-05 24.4 5.3 2.0 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos PF03372.23 EEQ40936.1 - 3.3e-05 23.5 0.0 5.9e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TBP PF00352.21 EEQ40938.1 - 3e-68 225.8 0.1 7.9e-33 112.3 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EEQ40938.1 - 2.6e-05 24.3 0.0 0.2 11.8 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EEQ40938.1 - 0.1 12.4 0.2 0.61 9.9 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Cgr1 PF03879.14 EEQ40939.1 - 1.5e-32 112.2 32.2 2e-32 111.8 32.2 1.1 1 0 0 1 1 1 1 Cgr1 family DUF2048 PF09752.9 EEQ40939.1 - 0.6 9.1 4.1 0.75 8.8 4.1 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 MRP-S26 PF14943.6 EEQ40939.1 - 0.64 9.9 22.1 0.82 9.6 22.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Pex24p PF06398.11 EEQ40940.1 - 4.3e-77 259.6 14.5 4.9e-77 259.4 14.5 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF2826 PF11442.8 EEQ40940.1 - 0.08 12.8 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) HIG_1_N PF04588.13 EEQ40941.1 - 4.2e-08 33.3 5.1 5.4e-07 29.7 4.2 2.4 2 1 0 2 2 2 1 Hypoxia induced protein conserved region BAR PF03114.18 EEQ40945.1 - 1.1e-49 169.3 2.6 1.2e-49 169.1 2.6 1.0 1 0 0 1 1 1 1 BAR domain DUF4164 PF13747.6 EEQ40945.1 - 0.027 14.8 4.9 0.074 13.3 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF2303 PF10065.9 EEQ40945.1 - 0.045 12.9 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Jnk-SapK_ap_N PF09744.9 EEQ40945.1 - 0.049 13.8 2.4 0.086 13.1 0.3 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 HAUS-augmin3 PF14932.6 EEQ40945.1 - 0.091 12.3 1.2 0.29 10.7 0.1 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 LPD34 PF18852.1 EEQ40945.1 - 0.092 12.3 1.2 2.9 7.4 0.4 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 34 NPA PF16469.5 EEQ40945.1 - 0.11 13.1 1.1 0.41 11.2 0.9 2.3 1 1 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Actin PF00022.19 EEQ40946.1 - 0.00015 20.5 0.1 0.0015 17.2 0.0 2.2 2 1 1 3 3 3 2 Actin Helicase_C_2 PF13307.6 EEQ40947.1 - 2.1e-44 151.7 0.3 3.6e-44 150.9 0.0 1.5 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EEQ40948.1 - 2.6e-55 186.8 1.9 4.3e-55 186.1 1.9 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EEQ40948.1 - 2.9e-43 147.8 0.4 5.5e-43 146.9 0.4 1.5 1 0 0 1 1 1 1 Helical and beta-bridge domain ResIII PF04851.15 EEQ40948.1 - 0.00046 20.2 0.1 0.017 15.1 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EEQ40948.1 - 0.00074 19.3 0.4 0.72 9.6 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase DUF2075 PF09848.9 EEQ40948.1 - 0.0047 16.2 0.1 0.25 10.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) YtxC PF08812.11 EEQ40948.1 - 0.026 14.1 2.1 0.81 9.3 0.1 3.0 3 0 0 3 3 3 0 YtxC-like family SNF2_N PF00176.23 EEQ40948.1 - 0.054 12.2 0.1 1.6 7.3 0.1 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 EEQ40948.1 - 0.062 13.6 2.8 7.3 6.9 0.0 3.3 3 1 1 4 4 4 0 AAA domain PhoH PF02562.16 EEQ40948.1 - 0.063 12.7 0.0 4.1 6.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Meis_PKNOX_N PF16493.5 EEQ40948.1 - 0.082 13.2 0.5 2.4 8.6 0.0 2.8 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 Exog_C PF18026.1 EEQ40948.1 - 1.8 8.7 5.0 8.9 6.5 0.2 3.3 3 1 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain ADK PF00406.22 EEQ40949.1 - 3.9e-41 140.6 0.0 4.9e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EEQ40949.1 - 3.8e-20 72.7 0.0 6.8e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EEQ40949.1 - 4.6e-13 48.9 0.0 7.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EEQ40949.1 - 0.00012 22.6 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ40949.1 - 0.0068 16.6 0.1 0.021 15.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EEQ40949.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Leo1 PF04004.13 EEQ40951.1 - 4.1e-44 150.3 0.6 9.5e-44 149.2 0.6 1.6 1 0 0 1 1 1 1 Leo1-like protein RhoGAP PF00620.27 EEQ40952.1 - 3e-36 124.5 0.0 4.8e-21 75.2 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain Med21 PF11221.8 EEQ40952.1 - 0.4 10.9 6.2 0.18 12.1 0.3 2.9 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Pkinase PF00069.25 EEQ40953.1 - 2.8e-71 240.0 0.0 3.3e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40953.1 - 1.1e-43 149.4 0.0 1.3e-43 149.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ40953.1 - 2e-08 33.9 0.0 4.2e-08 32.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEQ40953.1 - 1.3e-06 27.5 0.0 1.9e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EEQ40953.1 - 0.0028 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EEQ40953.1 - 0.09 12.4 0.1 0.94 9.1 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SCA7 PF08313.12 EEQ40954.1 - 2.6e-30 104.1 0.3 7.7e-30 102.6 0.3 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain DUF2043 PF09740.9 EEQ40954.1 - 0.79 10.4 5.1 0.28 11.9 0.4 2.6 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2043) Sgf11 PF08209.11 EEQ40955.1 - 7.6e-06 25.4 0.4 1.3e-05 24.7 0.4 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf_C2H2_13 PF18508.1 EEQ40955.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Zinc finger domain RR_TM4-6 PF06459.12 EEQ40955.1 - 0.75 9.6 5.8 0.33 10.7 3.5 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 K_channel_TID PF07941.11 EEQ40955.1 - 1.2 9.7 14.8 1.4 9.5 7.4 2.4 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF4451 PF14616.6 EEQ40956.1 - 4.8e-31 107.5 2.4 1.1e-30 106.3 2.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) zf-Di19 PF05605.12 EEQ40956.1 - 7 7.0 6.9 3.1 8.2 0.2 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Wyosine_form PF08608.12 EEQ40957.1 - 1.2e-22 80.0 0.0 3e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 EEQ40957.1 - 6.4e-22 78.7 0.0 1.7e-21 77.4 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 EEQ40957.1 - 1.9e-15 57.3 0.0 1.3e-14 54.6 0.0 2.3 2 1 0 2 2 2 1 Flavodoxin Phage_TTP_13 PF16463.5 EEQ40957.1 - 0.12 11.9 0.0 4.5 6.8 0.0 2.3 2 0 0 2 2 2 0 Phage tail tube protein family Glycos_transf_1 PF00534.20 EEQ40958.1 - 8.3e-25 87.3 0.0 1.4e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EEQ40958.1 - 1.7e-14 54.2 0.0 3.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EEQ40958.1 - 4.6e-10 40.1 0.0 1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EEQ40958.1 - 0.0035 17.8 0.4 0.017 15.6 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain ALG11_N PF15924.5 EEQ40958.1 - 0.1 12.6 1.4 24 4.9 0.0 3.0 1 1 1 2 2 2 0 ALG11 mannosyltransferase N-terminus PAP2 PF01569.21 EEQ40958.1 - 0.12 12.2 1.5 0.2 11.4 0.5 1.9 2 0 0 2 2 2 0 PAP2 superfamily DUF1992 PF09350.10 EEQ40959.1 - 2.8e-17 62.6 0.0 7.3e-17 61.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF4279 PF14106.6 EEQ40959.1 - 0.12 12.6 0.0 4.7 7.4 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) UPF0016 PF01169.19 EEQ40960.1 - 6.7e-38 128.9 29.5 8.3e-21 74.1 8.4 2.6 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 Presenilin PF01080.17 EEQ40960.1 - 0.0073 15.1 1.9 0.0073 15.1 1.9 1.5 2 0 0 2 2 2 1 Presenilin LysE PF01810.18 EEQ40960.1 - 0.4 10.1 15.5 1.1 8.7 4.5 2.6 2 1 0 2 2 2 0 LysE type translocator TerC PF03741.16 EEQ40960.1 - 9.1 5.9 13.1 0.47 10.1 5.2 2.3 2 1 0 2 2 2 0 Integral membrane protein TerC family Med8 PF10232.9 EEQ40961.1 - 4.8e-17 62.3 1.5 6.7e-17 61.9 1.5 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Rogdi_lz PF10259.9 EEQ40961.1 - 0.032 13.7 0.3 0.039 13.4 0.3 1.2 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein NPV_P10 PF05531.12 EEQ40961.1 - 0.048 14.1 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EHD_N PF16880.5 EEQ40961.1 - 0.073 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 N-terminal EH-domain containing protein ADH_zinc_N PF00107.26 EEQ40962.1 - 4.3e-21 75.2 0.0 3.1e-20 72.5 0.0 2.1 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ40962.1 - 8.5e-21 73.9 3.3 1.4e-20 73.2 3.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 EEQ40962.1 - 1.9e-06 27.3 0.1 3.1e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EEQ40962.1 - 2.8e-06 28.4 0.0 4.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EEQ40962.1 - 0.00012 21.5 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF364 PF04016.12 EEQ40962.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation GFO_IDH_MocA PF01408.22 EEQ40962.1 - 0.023 15.5 0.0 0.053 14.3 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 EEQ40962.1 - 0.049 13.8 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ELFV_dehydrog PF00208.21 EEQ40962.1 - 0.083 12.6 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.27 EEQ40962.1 - 0.1 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EEQ40962.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Oxidored_nitro PF00148.19 EEQ40962.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Gp_dh_N PF00044.24 EEQ40962.1 - 0.12 12.7 0.1 0.94 9.9 0.0 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EEQ40962.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NpwBP PF12622.7 EEQ40963.1 - 7.5e-09 36.2 1.5 7.5e-09 36.2 1.5 1.9 1 1 1 2 2 2 1 mRNA biogenesis factor Wbp11 PF09429.10 EEQ40963.1 - 0.00011 22.5 7.2 0.00011 22.5 7.2 2.1 2 0 0 2 2 2 1 WW domain binding protein 11 RRP36 PF06102.12 EEQ40963.1 - 0.22 11.5 10.5 0.31 11.0 10.5 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Mito_carr PF00153.27 EEQ40966.1 - 7.5e-72 237.3 1.0 1.8e-26 91.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.22 EEQ40967.1 - 9.3e-11 41.8 0.0 1.5e-10 41.1 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3535 PF12054.8 EEQ40968.1 - 9e-118 394.3 5.6 9.4e-117 390.9 0.9 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF3535) HEAT PF02985.22 EEQ40968.1 - 1.6e-13 49.6 2.0 0.69 10.3 0.0 8.9 7 1 1 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EEQ40968.1 - 9.1e-07 29.4 0.0 0.26 11.9 0.0 5.4 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EEQ40968.1 - 7.1e-05 23.1 3.7 0.14 12.5 0.0 6.2 7 1 0 7 7 7 1 HEAT repeats MSA-2c PF12238.8 EEQ40968.1 - 0.033 14.2 1.1 0.14 12.2 1.1 2.0 1 0 0 1 1 1 0 Merozoite surface antigen 2c TAF6_C PF07571.13 EEQ40968.1 - 0.065 13.6 0.0 58 4.1 0.0 4.5 5 0 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EEQ40968.1 - 0.068 13.4 0.0 9.4 6.5 0.0 4.2 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EEQ40968.1 - 0.078 13.0 4.0 0.22 11.5 0.7 3.1 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Ccdc124 PF06244.12 EEQ40970.1 - 5.4e-30 104.6 19.1 5.4e-30 104.6 19.1 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 ADH_N PF08240.12 EEQ40971.1 - 6.5e-25 87.1 0.1 1e-24 86.5 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EEQ40971.1 - 8e-19 67.9 0.0 1.3e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ40971.1 - 1.5e-09 39.0 0.0 2.8e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EEQ40971.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EEQ40971.1 - 0.00013 21.4 0.0 0.00019 20.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EEQ40971.1 - 0.00077 19.9 0.0 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding ThiF PF00899.21 EEQ40971.1 - 0.0014 18.1 0.1 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EEQ40971.1 - 0.0023 18.0 0.0 0.0062 16.6 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Glu_dehyd_C PF16912.5 EEQ40971.1 - 0.0039 16.7 0.0 0.0058 16.1 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 EEQ40971.1 - 0.0044 17.6 0.2 0.0081 16.7 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 EEQ40971.1 - 0.0047 17.4 0.0 0.0076 16.7 0.0 1.3 1 0 0 1 1 1 1 XdhC Rossmann domain adh_short PF00106.25 EEQ40971.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_3 PF01494.19 EEQ40971.1 - 0.012 14.9 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 EEQ40971.1 - 0.028 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EEQ40971.1 - 0.051 13.1 0.1 0.089 12.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EEQ40971.1 - 0.072 13.3 0.1 0.16 12.3 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.22 EEQ40971.1 - 0.15 12.9 0.0 0.29 12.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold HMGL-like PF00682.19 EEQ40973.1 - 2.2e-84 283.1 0.3 3e-84 282.7 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Mur_ligase_M PF08245.12 EEQ40975.1 - 2e-06 27.9 0.0 4.4e-05 23.6 0.0 2.7 1 1 0 1 1 1 1 Mur ligase middle domain Peripla_BP_1 PF00532.21 EEQ40975.1 - 0.0064 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding proteins and sugar binding domain of LacI family NAD_binding_6 PF08030.12 EEQ40975.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Mur_ligase_C PF02875.21 EEQ40975.1 - 0.054 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain HHH_8 PF14716.6 EEQ40975.1 - 0.12 12.8 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain eIF3m_C_helix PF18005.1 EEQ40976.1 - 0.0054 16.4 0.7 0.011 15.4 0.7 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Pkinase PF00069.25 EEQ40977.1 - 7.8e-69 232.0 0.0 1.4e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40977.1 - 5.3e-39 134.1 0.0 9e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ40977.1 - 2.4e-07 30.4 0.0 4.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ40977.1 - 0.0011 18.4 2.4 0.0015 17.9 0.6 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EEQ40977.1 - 0.0077 15.0 0.0 0.0077 15.0 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EEQ40977.1 - 0.035 14.0 0.2 0.72 9.7 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ40977.1 - 0.046 13.3 2.5 0.054 13.1 0.2 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase SUV3_C PF12513.8 EEQ40978.1 - 2.5e-14 52.9 0.2 6.4e-14 51.6 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EEQ40978.1 - 4.2e-13 49.6 0.0 1.1e-12 48.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Elicitin PF00964.17 EEQ40978.1 - 0.041 14.0 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 Elicitin SKI PF01202.22 EEQ40979.1 - 5.3e-13 49.4 0.0 6.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EEQ40979.1 - 6.9e-10 39.2 0.0 8.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EEQ40979.1 - 4.6e-09 36.9 0.0 7.6e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 EEQ40979.1 - 4e-05 23.4 0.1 0.00039 20.2 0.0 2.3 2 1 0 2 2 2 1 Cytidylate kinase AAA PF00004.29 EEQ40979.1 - 0.00094 19.6 0.4 0.0023 18.4 0.1 1.8 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EEQ40979.1 - 0.002 18.6 0.0 0.0046 17.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EEQ40979.1 - 0.0027 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase dNK PF01712.19 EEQ40979.1 - 0.0034 17.3 1.0 0.64 9.8 0.3 2.2 1 1 1 2 2 2 2 Deoxynucleoside kinase AAA_16 PF13191.6 EEQ40979.1 - 0.0086 16.5 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ40979.1 - 0.018 15.3 0.5 0.073 13.3 0.3 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EEQ40979.1 - 0.022 14.5 0.2 0.033 13.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain tRNA_NucTran2_2 PF13735.6 EEQ40979.1 - 0.026 14.5 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative AAA_28 PF13521.6 EEQ40979.1 - 0.029 14.6 0.7 0.083 13.1 0.5 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EEQ40979.1 - 0.033 13.5 0.1 0.067 12.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin CoaE PF01121.20 EEQ40979.1 - 0.037 13.7 0.2 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 Dephospho-CoA kinase PhoH PF02562.16 EEQ40979.1 - 0.057 12.9 0.9 0.1 12.0 0.9 1.4 1 0 0 1 1 1 0 PhoH-like protein IPT PF01745.16 EEQ40979.1 - 0.058 12.8 0.4 0.12 11.8 0.3 1.9 1 1 0 1 1 1 0 Isopentenyl transferase NB-ARC PF00931.22 EEQ40979.1 - 0.06 12.5 2.7 1.3 8.1 0.4 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 EEQ40979.1 - 0.092 12.3 0.2 0.17 11.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EEQ40979.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EEQ40979.1 - 0.13 12.2 0.1 0.33 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EEQ40979.1 - 0.15 11.8 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 EEQ40979.1 - 0.18 11.0 0.8 0.26 10.5 0.6 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) CbiA PF01656.23 EEQ40979.1 - 0.21 11.6 0.7 0.32 11.1 0.7 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 EEQ40979.1 - 0.33 10.6 1.5 10 5.8 0.1 2.3 1 1 0 2 2 2 0 Thymidylate kinase Ureide_permease PF07168.11 EEQ40980.1 - 0.028 13.2 0.2 0.041 12.6 0.2 1.2 1 0 0 1 1 1 0 Ureide permease adh_short PF00106.25 EEQ40981.1 - 2.9e-12 46.5 0.0 3.2e-09 36.5 0.0 3.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ40981.1 - 1.9e-05 24.3 0.0 0.00024 20.8 0.0 2.4 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ40981.1 - 0.16 11.9 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 KR domain Thiolase_N PF00108.23 EEQ40984.1 - 4.1e-95 318.1 4.6 6.7e-95 317.4 4.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EEQ40984.1 - 1.8e-44 150.3 0.2 4.4e-44 149.1 0.2 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EEQ40984.1 - 5.5e-05 22.9 0.3 0.00011 21.8 0.3 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain MatB PF16449.5 EEQ40984.1 - 0.07 12.9 0.6 2 8.2 0.0 2.3 1 1 1 2 2 2 0 Fimbrillin MatB ACP_syn_III PF08545.10 EEQ40984.1 - 0.11 12.4 2.6 1.2 9.1 0.1 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FLILHELTA PF10306.9 EEQ40985.1 - 1.1e-29 102.6 0.1 2.1e-29 101.7 0.1 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EEQ40985.1 - 0.11 13.1 0.8 0.24 11.9 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) Pkinase PF00069.25 EEQ40986.1 - 5e-65 219.5 0.0 6e-65 219.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40986.1 - 2.3e-24 86.1 0.0 3.3e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ40986.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EEQ40986.1 - 0.00022 21.2 0.0 0.0094 15.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EEQ40986.1 - 0.036 13.7 0.1 0.059 12.9 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 EEQ40986.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EEQ40986.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tim54 PF11711.8 EEQ40989.1 - 0.62 8.8 11.8 0.89 8.3 11.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 EEQ40989.1 - 2.6 7.2 4.2 2.5 7.3 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GREB1 PF15782.5 EEQ40989.1 - 4.6 4.2 12.9 5.2 4.1 12.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 EEQ40990.1 - 5.7e-35 121.0 0.0 8.4e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40990.1 - 3.4e-18 65.9 0.0 4.3e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EEQ40990.1 - 0.0069 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EEQ40990.1 - 0.034 12.9 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EEQ40990.1 - 0.059 13.3 0.0 0.38 10.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EEQ40990.1 - 0.1 11.9 0.0 0.45 9.8 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Pkinase PF00069.25 EEQ40991.1 - 3.7e-58 197.0 1.4 1.2e-57 195.3 0.3 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ40991.1 - 1.4e-29 103.2 0.3 8.3e-28 97.4 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ40991.1 - 0.00082 18.4 0.3 0.0014 17.7 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain DUF2779 PF11074.8 EEQ40991.1 - 0.062 13.8 0.1 0.16 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Kinase-like PF14531.6 EEQ40991.1 - 0.063 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FA_hydroxylase PF04116.13 EEQ40992.1 - 1.1e-22 80.8 15.5 1.1e-22 80.8 15.5 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Porphobil_deam PF01379.20 EEQ40993.1 - 2.3e-71 239.5 0.0 3e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EEQ40993.1 - 6.1e-22 77.8 0.1 1.1e-21 77.0 0.1 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain ERCC4 PF02732.15 EEQ40995.1 - 2.7e-22 79.7 0.0 8.1e-22 78.1 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain PRTP PF01366.18 EEQ40995.1 - 0.02 13.0 0.5 0.033 12.3 0.5 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein RMI1_N PF08585.12 EEQ40996.1 - 1.1e-14 54.8 0.0 1.8e-14 54.0 0.0 1.3 1 1 0 1 1 1 1 RecQ mediated genome instability protein MTHFR PF02219.17 EEQ40997.1 - 6.1e-105 350.6 0.0 4.4e-104 347.8 0.0 1.9 2 0 0 2 2 2 1 Methylenetetrahydrofolate reductase Ribonuclease_T2 PF00445.18 EEQ40998.1 - 5.7e-40 137.5 0.1 8.2e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family ATG27 PF09451.10 EEQ40999.1 - 6.1e-61 206.6 0.1 7.8e-61 206.2 0.1 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EEQ40999.1 - 2.2e-05 24.6 0.1 0.003 17.6 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat DUF2165 PF09933.9 EEQ40999.1 - 0.074 13.1 0.4 0.074 13.1 0.4 1.5 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) Ldh_1_N PF00056.23 EEQ41000.1 - 1.5e-43 148.3 1.0 2.5e-43 147.6 1.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EEQ41000.1 - 1.1e-34 119.8 0.0 2.2e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EEQ41000.1 - 0.044 12.8 0.1 0.096 11.7 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family CTV_P33 PF07184.11 EEQ41000.1 - 0.081 12.0 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Citrus tristeza virus P33 protein Beta-lactamase PF00144.24 EEQ41001.1 - 1.4e-46 159.3 0.0 1.7e-46 159.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Histidinol_dh PF00815.20 EEQ41002.1 - 1.3e-156 521.7 3.3 1.3e-156 521.7 3.3 1.6 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 EEQ41002.1 - 2.2e-20 72.2 0.2 6.2e-20 70.8 0.2 1.8 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EEQ41002.1 - 2.5e-14 53.5 0.1 2.5e-14 53.5 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_1 PF00515.28 EEQ41003.1 - 8.8e-23 79.1 3.3 8.2e-07 28.6 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ41003.1 - 6.7e-18 64.1 0.2 1.5e-05 24.5 0.0 4.3 2 1 2 4 4 4 3 TPR repeat TPR_2 PF07719.17 EEQ41003.1 - 4.1e-17 60.8 8.5 0.00031 20.6 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ41003.1 - 1.2e-16 60.0 3.8 0.00066 20.3 0.0 5.5 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ41003.1 - 2.2e-16 58.9 2.7 0.00073 19.7 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ41003.1 - 4.2e-14 52.9 2.7 0.00021 21.8 0.6 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ41003.1 - 1e-11 44.1 2.5 0.033 14.4 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ41003.1 - 1.9e-11 44.3 6.1 0.13 12.8 0.1 4.9 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ41003.1 - 1.8e-08 34.4 1.2 0.004 17.3 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.6 EEQ41003.1 - 7.4e-06 26.2 5.1 1.3 9.4 0.3 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ41003.1 - 2.4e-05 24.5 3.7 0.0084 16.4 0.0 3.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ41003.1 - 6.6e-05 23.3 4.1 8.3 7.3 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ41003.1 - 9.9e-05 22.1 0.1 2.9 8.1 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ41003.1 - 0.00015 21.9 1.5 0.011 15.9 0.1 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Ring_hydroxyl_A PF00848.19 EEQ41004.1 - 2.5e-26 93.0 0.0 3.8e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 EEQ41004.1 - 4.7e-16 58.5 0.2 1.2e-15 57.2 0.2 1.7 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain ARID PF01388.21 EEQ41005.1 - 2e-15 57.2 0.0 1e-14 55.0 0.0 2.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Glyco_transf_34 PF05637.12 EEQ41006.1 - 3.5e-70 236.4 0.3 4.2e-70 236.2 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family zf-RING_2 PF13639.6 EEQ41007.1 - 3.2e-10 40.2 9.6 5.9e-10 39.3 9.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EEQ41007.1 - 2.8e-08 33.5 8.9 5.6e-08 32.5 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ41007.1 - 4.2e-08 32.9 8.4 7.7e-08 32.1 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ41007.1 - 5e-08 32.7 9.4 7.3e-08 32.2 9.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ41007.1 - 3.6e-07 30.1 3.0 3.6e-07 30.1 3.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EEQ41007.1 - 2.5e-06 27.7 7.5 4.7e-06 26.8 7.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EEQ41007.1 - 6e-06 26.3 8.6 1.4e-05 25.2 8.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EEQ41007.1 - 1.2e-05 25.1 11.1 1.9e-05 24.4 11.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ41007.1 - 2.7e-05 24.0 5.2 5e-05 23.2 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 EEQ41007.1 - 0.0048 16.7 3.0 0.0081 16.0 3.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 EEQ41007.1 - 0.031 14.4 6.7 0.054 13.6 6.7 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EEQ41007.1 - 0.031 14.3 4.8 0.048 13.7 4.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EEQ41007.1 - 0.56 10.0 8.3 1.5 8.7 8.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EEQ41007.1 - 0.78 9.7 7.0 1.7 8.6 7.0 1.5 1 1 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 EEQ41007.1 - 2.2 8.6 9.0 3.3 8.0 8.3 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain IMS PF00817.20 EEQ41008.1 - 3.3e-38 131.0 0.0 1.2e-37 129.2 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family zf_UBZ PF18439.1 EEQ41008.1 - 2.4e-06 27.0 0.1 4.4e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Ferric_reduct PF01794.19 EEQ41009.1 - 2.5e-17 63.1 11.9 2.5e-17 63.1 11.9 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EEQ41009.1 - 1e-09 38.7 0.0 3.1e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EEQ41009.1 - 1.9e-06 27.9 0.3 5.1e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ada_Zn_binding PF02805.16 EEQ41010.1 - 1.5e-20 73.0 1.3 3.1e-20 72.0 1.3 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EEQ41010.1 - 0.00073 19.6 0.0 0.0021 18.1 0.0 1.8 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EEQ41010.1 - 0.00093 19.4 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Pkinase PF00069.25 EEQ41011.1 - 2e-67 227.4 0.0 3e-67 226.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41011.1 - 6.1e-38 130.6 0.0 8.3e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ41011.1 - 2.4e-08 33.6 0.0 1.7e-07 30.8 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EEQ41011.1 - 0.00083 18.2 0.2 0.0039 16.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 EEQ41011.1 - 0.039 14.1 0.0 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 ABC1 family Aminotran_3 PF00202.21 EEQ41012.1 - 2.7e-113 378.7 0.0 3.1e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Longin_2 PF18639.1 EEQ41013.1 - 5.7e-07 29.6 0.0 0.00025 21.0 0.0 2.9 1 1 1 2 2 2 2 Yeast longin domain FNIP_N PF14636.6 EEQ41013.1 - 0.0011 19.9 0.2 0.0011 19.9 0.2 4.4 3 2 1 4 4 4 1 Folliculin-interacting protein N-terminus SRI PF08236.11 EEQ41014.1 - 3.7e-25 87.9 3.0 3.7e-25 87.9 3.0 2.5 2 1 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EEQ41014.1 - 2.8e-18 66.9 0.1 2.8e-18 66.9 0.1 4.2 2 2 1 3 3 3 1 SET domain AWS PF17907.1 EEQ41014.1 - 9.9e-14 51.1 11.5 9.9e-14 51.1 11.5 1.9 2 0 0 2 2 2 1 AWS domain WW PF00397.26 EEQ41014.1 - 2.4e-08 33.9 0.6 4.9e-08 32.9 0.6 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.11 EEQ41014.1 - 1.5e-07 31.3 1.5 3.6e-07 30.1 0.4 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain NAD_Gly3P_dh_N PF01210.23 EEQ41015.1 - 3.2e-48 163.7 0.0 4.9e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EEQ41015.1 - 2.7e-42 144.4 0.1 5.3e-42 143.5 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EEQ41015.1 - 0.016 15.8 0.0 2.2 8.9 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EEQ41015.1 - 0.098 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-C2H2 PF00096.26 EEQ41016.1 - 1e-10 41.5 3.7 4.5e-05 23.7 1.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ41016.1 - 8.5e-09 35.5 2.5 0.0042 17.8 0.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ41016.1 - 0.0053 17.0 2.2 0.71 10.2 0.4 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EEQ41016.1 - 0.021 14.9 3.6 0.75 9.9 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EEQ41016.1 - 0.063 13.9 2.8 0.11 13.1 0.1 2.5 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-LYAR PF08790.11 EEQ41016.1 - 0.086 12.8 0.6 7.8 6.5 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 EEQ41016.1 - 0.13 12.1 1.9 0.65 9.8 0.1 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_15 PF17032.5 EEQ41016.1 - 0.14 12.9 1.2 0.3 11.9 1.2 1.5 1 0 0 1 1 1 0 zinc-ribbon family LIM PF00412.22 EEQ41016.1 - 0.29 11.4 1.8 1.7 8.9 1.9 2.0 1 1 0 1 1 1 0 LIM domain zf_UBZ PF18439.1 EEQ41016.1 - 0.36 10.5 1.5 21 4.8 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 EEQ41016.1 - 0.54 10.8 7.4 11 6.6 0.2 3.3 3 1 0 3 3 3 0 Zinc-finger double domain zf-C2H2_3 PF13878.6 EEQ41016.1 - 5.4 6.9 5.5 2.3 8.1 1.1 2.4 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO ING PF12998.7 EEQ41017.1 - 3.9e-25 88.4 0.0 7.1e-25 87.5 0.0 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EEQ41017.1 - 1.4e-05 24.8 7.5 2.6e-05 24.0 7.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EEQ41017.1 - 0.014 15.0 1.7 0.025 14.1 1.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 EEQ41017.1 - 0.61 10.4 3.3 1.3 9.3 3.3 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain GHMP_kinases_N PF00288.26 EEQ41018.1 - 0.12 12.7 2.1 0.16 12.3 0.1 2.2 2 1 1 3 3 3 0 GHMP kinases N terminal domain Ras PF00071.22 EEQ41019.1 - 3.4e-57 192.6 0.1 4.3e-57 192.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EEQ41019.1 - 2.4e-21 76.1 0.0 3.7e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EEQ41019.1 - 1.5e-08 34.3 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EEQ41019.1 - 5.2e-05 22.9 0.2 0.0003 20.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EEQ41019.1 - 0.0003 20.8 0.0 0.00049 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ41019.1 - 0.00045 20.2 0.6 1.2 9.0 0.0 2.7 1 1 1 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 EEQ41019.1 - 0.0097 15.3 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MSA-2c PF12238.8 EEQ41019.1 - 2.2 8.3 8.6 3.2 7.7 8.6 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c SRP-alpha_N PF04086.13 EEQ41019.1 - 2.7 7.8 7.4 4.2 7.2 5.5 1.9 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DAD PF02109.16 EEQ41020.1 - 2.8e-41 140.2 1.7 3.9e-41 139.8 1.7 1.2 1 0 0 1 1 1 1 DAD family RnlA_toxin PF15935.5 EEQ41020.1 - 0.21 11.4 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 RNase LS, bacterial toxin Y_phosphatase2 PF03162.13 EEQ41021.1 - 5.3e-51 172.5 0.0 6.1e-51 172.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EEQ41021.1 - 3.7e-06 27.1 0.0 9.6e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 EEQ41021.1 - 0.0077 16.0 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PdxA PF04166.12 EEQ41022.1 - 0.0091 15.4 0.2 0.035 13.5 0.1 1.9 1 1 0 2 2 2 1 Pyridoxal phosphate biosynthetic protein PdxA DUF1180 PF06679.12 EEQ41023.1 - 0.26 11.7 1.9 0.37 11.2 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) GSHPx PF00255.19 EEQ41024.1 - 1.9e-47 159.3 0.1 2.5e-47 158.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EEQ41024.1 - 4e-06 26.8 0.1 5.6e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EEQ41024.1 - 2.5e-05 24.0 0.1 0.00011 22.0 0.1 2.0 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.6 EEQ41024.1 - 0.0096 16.4 0.0 0.026 15.0 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4174) Zn_clus PF00172.18 EEQ41025.1 - 1.4e-06 28.3 13.3 2.4e-06 27.6 13.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EEQ41026.1 - 7.4e-27 94.2 31.5 2.2e-18 66.3 7.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EEQ41026.1 - 2.4e-08 33.3 9.8 2.4e-08 33.3 9.8 2.4 1 1 2 3 3 3 1 MFS_1 like family Sugar_tr PF00083.24 EEQ41026.1 - 3.3e-06 26.2 12.2 3.3e-06 26.2 12.2 2.2 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.6 EEQ41026.1 - 5.8e-06 25.1 31.1 0.004 15.8 10.5 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein CRPA PF05745.11 EEQ41026.1 - 4.1 7.4 7.6 0.65 10.0 0.1 3.0 2 2 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) AA_permease PF00324.21 EEQ41027.1 - 5.3e-115 384.8 48.2 6.7e-115 384.4 48.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ41027.1 - 1.7e-42 145.8 52.3 2.1e-42 145.5 52.3 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3767 PF12597.8 EEQ41027.1 - 0.0031 17.3 0.1 0.0087 15.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Phage_holin_2_2 PF10746.9 EEQ41027.1 - 0.25 11.0 3.1 0.95 9.2 0.1 3.3 3 0 0 3 3 3 0 Phage holin T7 family, holin superfamily II Acetyltransf_9 PF13527.7 EEQ41028.1 - 0.00016 21.7 1.3 0.0012 18.9 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EEQ41028.1 - 0.00078 19.8 0.8 0.0091 16.4 0.7 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ41028.1 - 0.0044 17.2 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ41028.1 - 0.046 13.7 0.2 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-C2H2 PF00096.26 EEQ41029.1 - 1.7e-15 56.5 16.8 2e-06 27.9 1.1 4.0 4 0 0 4 4 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ41029.1 - 5.5e-12 45.5 14.0 1e-07 32.1 0.6 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ41029.1 - 1.5e-11 44.1 11.1 0.0018 18.9 0.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EEQ41029.1 - 9.8e-10 38.5 2.0 0.0073 16.6 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 EEQ41029.1 - 2.2e-07 30.7 10.2 7.7e-05 22.6 1.8 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 EEQ41029.1 - 6.8e-06 25.9 5.6 0.46 10.5 0.0 3.5 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-met PF12874.7 EEQ41029.1 - 2.3e-05 24.6 5.4 0.027 14.9 0.5 3.8 4 0 0 4 4 3 2 Zinc-finger of C2H2 type Zn-C2H2_12 PF18112.1 EEQ41029.1 - 0.004 17.6 1.1 0.093 13.2 0.1 2.7 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain Zn-ribbon_8 PF09723.10 EEQ41029.1 - 0.0049 17.0 1.3 0.012 15.7 1.3 1.6 1 0 0 1 1 1 1 Zinc ribbon domain zf_UBZ PF18439.1 EEQ41029.1 - 0.0075 15.8 2.1 0.56 9.8 0.1 2.6 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EEQ41029.1 - 0.0076 16.5 2.3 0.012 15.8 1.5 1.8 2 0 0 2 2 1 1 Drought induced 19 protein (Di19), zinc-binding RNA_pol_Rpb1_1 PF04997.12 EEQ41029.1 - 0.01 15.2 0.5 0.029 13.7 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase Rpb1, domain 1 zf-nanos PF05741.13 EEQ41029.1 - 0.014 15.6 1.6 0.38 11.0 0.2 2.4 2 0 0 2 2 2 0 Nanos RNA binding domain DZR PF12773.7 EEQ41029.1 - 0.03 14.3 0.8 0.092 12.8 0.8 1.8 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.6 EEQ41029.1 - 0.044 13.7 0.9 3.7 7.6 0.1 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-AN1 PF01428.16 EEQ41029.1 - 0.046 13.9 3.4 4.5 7.5 0.7 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2H2_2 PF12756.7 EEQ41029.1 - 0.12 12.7 3.7 0.88 9.9 0.1 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 EEQ41029.1 - 0.12 12.4 7.1 0.7 10.0 0.4 3.2 2 1 1 3 3 3 0 BED zinc finger GAGA PF09237.11 EEQ41029.1 - 0.14 12.0 4.4 4.5 7.2 0.0 2.6 2 1 1 3 3 2 0 GAGA factor zf-H2C2_5 PF13909.6 EEQ41029.1 - 0.27 11.1 9.8 1.7 8.4 0.2 3.6 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 EEQ41029.1 - 0.57 10.0 0.1 0.57 10.0 0.1 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type XPA_N PF01286.18 EEQ41029.1 - 1 9.5 4.1 5.4 7.2 0.5 2.8 3 0 0 3 3 3 0 XPA protein N-terminal zf-LYAR PF08790.11 EEQ41029.1 - 2.6 8.0 5.2 8.7 6.4 0.1 2.8 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Zn_ribbon_recom PF13408.6 EEQ41029.1 - 3.6 8.2 10.3 0.46 11.0 4.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain ADK_lid PF05191.14 EEQ41029.1 - 5.2 7.1 6.8 0.52 10.3 1.1 2.4 3 0 0 3 3 2 0 Adenylate kinase, active site lid Carn_acyltransf PF00755.20 EEQ41030.1 - 2.8e-138 462.2 0.0 3.6e-138 461.8 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF5097 PF17020.5 EEQ41030.1 - 0.13 12.6 0.6 0.5 10.7 0.6 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) GCV_T PF01571.21 EEQ41031.1 - 0.0035 16.8 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain PRD_Mga PF08270.11 EEQ41031.1 - 0.035 13.8 0.9 0.048 13.3 0.3 1.4 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) PRD domain CDC48_2 PF02933.17 EEQ41031.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 eIF2_C PF09173.11 EEQ41033.1 - 1.9e-34 117.8 0.4 4.3e-34 116.6 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EEQ41033.1 - 8.8e-23 80.9 0.1 7.6e-22 77.8 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EEQ41033.1 - 3.4e-11 43.4 2.6 3.8e-11 43.2 0.6 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ41033.1 - 0.0051 16.9 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EEQ41033.1 - 0.0068 16.3 0.1 0.064 13.2 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase DNA_ligase_ZBD PF03119.16 EEQ41033.1 - 0.053 13.5 0.0 0.25 11.4 0.0 2.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain MMR_HSR1_Xtn PF16897.5 EEQ41033.1 - 0.066 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ProQ_C PF17516.2 EEQ41033.1 - 0.072 12.5 0.2 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 ProQ C-terminal domain DUF1936 PF09151.10 EEQ41033.1 - 0.16 11.9 2.0 0.53 10.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) RGS PF00615.19 EEQ41034.1 - 1.1e-17 64.4 5.4 2.5e-17 63.3 2.5 3.0 2 1 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.21 EEQ41034.1 - 7.1e-14 51.6 0.3 4.2e-13 49.1 0.0 2.4 3 0 0 3 3 3 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ORC4_C PF14629.6 EEQ41035.1 - 5.9e-43 146.8 0.9 1.3e-42 145.6 0.9 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EEQ41035.1 - 2.4e-10 41.1 0.0 7.6e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EEQ41035.1 - 4.9e-08 33.3 0.1 2e-07 31.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EEQ41035.1 - 4e-06 27.3 0.1 1.5e-05 25.5 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EEQ41035.1 - 0.00061 19.5 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 EEQ41035.1 - 0.0035 16.9 0.0 0.01 15.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EEQ41035.1 - 0.0046 17.0 0.0 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ORC3_N PF07034.11 EEQ41035.1 - 0.0051 16.0 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus TniB PF05621.11 EEQ41035.1 - 0.041 13.3 0.1 2.5 7.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 EEQ41035.1 - 0.061 13.4 0.1 0.3 11.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_19 PF13245.6 EEQ41035.1 - 0.12 12.7 0.0 0.43 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain CYSTM PF12734.7 EEQ41036.1 - 6.8e-06 26.3 63.5 76 3.7 63.5 4.7 1 1 0 1 1 1 1 Cysteine-rich TM module stress tolerance GRP PF07172.11 EEQ41036.1 - 1.8 9.3 15.9 2.6 8.8 15.9 1.3 1 0 0 1 1 1 0 Glycine rich protein family OPT PF03169.15 EEQ41037.1 - 3.3e-175 584.3 41.6 4e-175 584.0 41.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.11 EEQ41037.1 - 1.1 9.6 9.3 2.6 8.3 6.7 3.0 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA Ribosomal_S7 PF00177.21 EEQ41038.1 - 2.4e-35 121.4 3.1 3.6e-35 120.8 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e MFS_1 PF07690.16 EEQ41040.1 - 5.3e-15 55.2 43.6 7.9e-15 54.6 43.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA PF00004.29 EEQ41041.1 - 4.3e-42 143.7 0.0 7.3e-42 142.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EEQ41041.1 - 3e-28 97.6 0.0 2e-27 95.0 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EEQ41041.1 - 9.7e-23 80.0 5.5 9.7e-23 80.0 5.5 2.1 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EEQ41041.1 - 2.6e-07 30.3 0.0 3.4e-06 26.8 0.0 2.7 3 0 0 3 3 3 1 AAA+ lid domain AAA_16 PF13191.6 EEQ41041.1 - 1.8e-06 28.4 0.5 0.00035 21.0 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EEQ41041.1 - 7.5e-06 26.0 0.0 4e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EEQ41041.1 - 8.8e-06 26.1 1.1 0.011 16.1 0.0 4.1 5 0 0 5 5 4 1 RNA helicase IstB_IS21 PF01695.17 EEQ41041.1 - 2.7e-05 24.0 0.0 0.00013 21.8 0.0 2.1 2 1 1 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.12 EEQ41041.1 - 2.8e-05 23.9 0.0 5.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EEQ41041.1 - 3.6e-05 23.0 0.0 0.0001 21.5 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EEQ41041.1 - 7.6e-05 23.0 0.4 0.011 16.0 0.0 2.9 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 EEQ41041.1 - 0.00016 22.2 0.1 0.00071 20.1 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.6 EEQ41041.1 - 0.00021 21.3 0.1 0.0011 19.0 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.6 EEQ41041.1 - 0.00032 21.1 0.1 0.049 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EEQ41041.1 - 0.00059 19.1 0.0 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 EEQ41041.1 - 0.0011 19.1 0.0 0.0037 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EEQ41041.1 - 0.0017 18.5 0.1 0.005 17.0 0.0 2.0 2 1 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EEQ41041.1 - 0.0019 18.0 0.0 0.0095 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EEQ41041.1 - 0.0051 16.2 0.2 4.5 6.6 0.0 3.7 2 1 2 4 4 4 1 KaiC AAA_25 PF13481.6 EEQ41041.1 - 0.013 15.0 0.1 0.4 10.2 0.1 2.5 1 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EEQ41041.1 - 0.028 13.8 0.0 0.081 12.3 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EEQ41041.1 - 0.038 13.5 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 EEQ41041.1 - 0.056 13.3 0.0 0.37 10.6 0.0 2.1 1 1 0 1 1 1 0 Bacterial dnaA protein Torsin PF06309.11 EEQ41041.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Torsin Parvo_NS1 PF01057.17 EEQ41041.1 - 0.062 12.4 0.0 0.095 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EEQ41041.1 - 0.063 12.7 0.1 0.15 11.5 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 EEQ41041.1 - 0.068 13.1 0.0 0.68 9.8 0.0 2.3 2 1 1 3 3 2 0 NACHT domain Zeta_toxin PF06414.12 EEQ41041.1 - 0.074 12.3 0.6 1.1 8.5 0.1 2.5 2 1 1 3 3 2 0 Zeta toxin Sigma54_activat PF00158.26 EEQ41041.1 - 0.095 12.4 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain CPT PF07931.12 EEQ41041.1 - 0.14 12.0 0.0 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Cytidylate_kin PF02224.18 EEQ41041.1 - 0.15 11.8 0.8 0.5 10.1 0.0 2.2 2 1 1 3 3 3 0 Cytidylate kinase DUF2098 PF09871.9 EEQ41041.1 - 0.24 11.8 2.2 0.61 10.5 2.2 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) NCBP3 PF10309.9 EEQ41042.1 - 2.7e-24 84.8 0.7 7.2e-24 83.4 0.7 1.8 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 CTNNB1_binding PF08347.11 EEQ41042.1 - 0.013 15.7 2.5 0.031 14.5 2.5 1.8 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Selenoprotein_S PF06936.11 EEQ41042.1 - 0.013 15.3 2.5 0.013 15.3 2.5 1.8 2 0 0 2 2 2 0 Selenoprotein S (SelS) YscJ_FliF_C PF08345.11 EEQ41042.1 - 0.19 12.0 4.1 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal LSM PF01423.22 EEQ41043.1 - 6.8e-21 73.7 0.9 8.1e-21 73.5 0.9 1.1 1 0 0 1 1 1 1 LSM domain PIG-U PF06728.13 EEQ41044.1 - 1.4e-107 360.1 31.6 1.7e-107 359.8 31.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Peptidase_M16 PF00675.20 EEQ41045.1 - 1.6e-20 73.6 0.0 2.6e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EEQ41045.1 - 2.9e-06 27.4 0.0 1.2e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpb6 PF01192.22 EEQ41047.1 - 7.7e-16 57.7 0.1 1.2e-15 57.2 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 EF-hand_6 PF13405.6 EEQ41048.1 - 2.1e-05 24.1 0.5 0.00031 20.4 0.2 2.9 2 1 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EEQ41048.1 - 0.011 16.2 0.3 0.033 14.6 0.2 2.1 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EEQ41048.1 - 0.015 14.8 0.7 3.1 7.6 0.1 3.6 3 1 0 3 3 3 0 EF hand DUF4035 PF13227.6 EEQ41048.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) O-ag_pol_Wzy PF14296.6 EEQ41049.1 - 0.00065 18.5 1.3 0.00077 18.2 1.3 1.0 1 0 0 1 1 1 1 O-antigen polysaccharide polymerase Wzy Plasmod_dom_1 PF09715.10 EEQ41049.1 - 0.0025 17.8 0.2 0.0056 16.7 0.0 1.7 2 0 0 2 2 2 1 Plasmodium protein of unknown function (Plasmod_dom_1) Actin PF00022.19 EEQ41050.1 - 1.3e-124 415.9 0.0 1.2e-123 412.8 0.0 1.9 1 1 0 1 1 1 1 Actin eRF1_1 PF03463.15 EEQ41051.1 - 0.037 14.0 0.0 0.078 13.0 0.0 1.5 1 0 0 1 1 1 0 eRF1 domain 1 UPRTase PF14681.6 EEQ41052.1 - 2.8e-76 255.6 0.0 3.9e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EEQ41052.1 - 0.056 12.9 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 EEQ41052.1 - 0.097 12.7 0.2 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Ubiquitin_2 PF14560.6 EEQ41053.1 - 3.9e-27 94.5 0.1 1.1e-26 93.1 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-like domain CAP_GLY PF01302.25 EEQ41053.1 - 5.3e-21 74.4 0.9 9.5e-21 73.6 0.9 1.4 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 EEQ41053.1 - 6.9e-05 22.5 0.0 0.094 12.5 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin family PGA2 PF07543.12 EEQ41054.1 - 5.1e-10 39.5 12.3 2.7e-07 30.6 12.3 2.1 1 1 0 1 1 1 1 Protein trafficking PGA2 CBP_BcsG PF11658.8 EEQ41054.1 - 0.041 12.3 0.3 0.047 12.1 0.3 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG DUF4083 PF13314.6 EEQ41054.1 - 0.062 13.3 0.7 0.34 10.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) O-antigen_lig PF13425.6 EEQ41054.1 - 0.064 12.0 0.3 0.074 11.8 0.3 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein End3 PF12761.7 EEQ41054.1 - 0.17 12.0 7.3 0.22 11.7 7.3 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 EMC3_TMCO1 PF01956.16 EEQ41054.1 - 0.29 10.9 1.9 0.41 10.4 1.9 1.3 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Whib PF02467.16 EEQ41055.1 - 0.038 14.6 0.7 0.11 13.1 0.7 1.7 1 0 0 1 1 1 0 Transcription factor WhiB WD40 PF00400.32 EEQ41056.1 - 1.2e-14 54.4 3.4 0.00012 22.7 0.2 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat PHTB1_N PF14727.6 EEQ41056.1 - 0.034 13.5 0.0 4 6.7 0.0 2.2 2 0 0 2 2 2 0 PTHB1 N-terminus ANAPC4_WD40 PF12894.7 EEQ41056.1 - 0.067 13.5 0.0 0.93 9.8 0.0 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PGA2 PF07543.12 EEQ41056.1 - 0.98 9.4 8.2 2.3 8.2 8.2 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 RNA_pol_3_Rpc31 PF11705.8 EEQ41057.1 - 4.8e-44 151.3 14.5 6e-44 151.0 14.5 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 RXT2_N PF08595.11 EEQ41057.1 - 5.6 7.0 7.8 9.2 6.3 7.8 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal C2 PF00168.30 EEQ41058.1 - 1.9e-09 37.7 0.0 3.4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain MRP-L20 PF12824.7 EEQ41060.1 - 1.8e-53 181.1 3.0 2e-53 180.9 3.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_32 PF13565.6 EEQ41060.1 - 0.0046 17.5 0.0 0.014 16.0 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Neugrin PF06413.11 EEQ41060.1 - 0.0072 16.4 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Neugrin DNA_ligase_A_C PF04679.15 EEQ41060.1 - 0.13 12.9 0.3 0.39 11.4 0.1 1.9 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region Ndc80_HEC PF03801.13 EEQ41061.1 - 1.4e-48 164.4 2.2 2e-48 163.9 0.0 2.4 2 0 0 2 2 2 1 HEC/Ndc80p family FliJ PF02050.16 EEQ41061.1 - 7.3e-05 23.0 5.1 7.3e-05 23.0 5.1 4.8 2 2 2 4 4 4 2 Flagellar FliJ protein DUF5595 PF18077.1 EEQ41061.1 - 0.00026 21.0 3.9 0.00026 21.0 3.9 5.4 3 2 3 6 6 6 1 Domain of unknown function (DUF5595) TPR_MLP1_2 PF07926.12 EEQ41061.1 - 0.0059 16.7 43.5 0.03 14.4 9.0 4.7 2 2 0 3 3 3 2 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.7 EEQ41061.1 - 0.006 16.7 9.6 0.006 16.7 9.6 3.5 2 1 1 3 3 3 2 Tropomyosin like Phage_GP20 PF06810.11 EEQ41061.1 - 0.014 15.2 7.1 0.014 15.2 7.1 3.9 2 2 2 4 4 4 0 Phage minor structural protein GP20 Rogdi_lz PF10259.9 EEQ41061.1 - 0.017 14.6 5.0 0.035 13.5 4.9 1.7 1 1 0 1 1 1 0 Rogdi leucine zipper containing protein DHR10 PF18595.1 EEQ41061.1 - 0.032 14.3 42.0 0.2 11.8 4.7 3.9 3 1 0 3 3 3 0 Designed helical repeat protein 10 domain DUF1664 PF07889.12 EEQ41061.1 - 0.088 12.8 27.8 0.4 10.7 0.9 4.5 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 EEQ41061.1 - 0.4 10.1 46.3 0.058 12.9 2.4 3.4 1 1 2 3 3 3 0 Golgin subfamily A member 5 MscS_porin PF12795.7 EEQ41061.1 - 0.72 9.4 30.2 0.053 13.1 0.5 3.9 3 1 0 3 3 3 0 Mechanosensitive ion channel porin domain Lebercilin PF15619.6 EEQ41061.1 - 2.5 7.7 35.7 6.1 6.5 20.7 3.1 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cob_adeno_trans PF01923.18 EEQ41061.1 - 2.6 8.2 11.3 0.6 10.2 0.9 3.1 2 1 0 2 2 2 0 Cobalamin adenosyltransferase SpecificRecomb PF10136.9 EEQ41061.1 - 5.1 5.3 13.4 0.24 9.7 1.8 2.2 2 0 0 2 2 2 0 Site-specific recombinase CCDC-167 PF15188.6 EEQ41061.1 - 9.1 6.7 35.6 0.036 14.4 2.6 4.5 3 2 0 3 3 3 0 Coiled-coil domain-containing protein 167 SURF6 PF04935.12 EEQ41062.1 - 0.65 9.8 7.1 2.2 8.0 2.3 2.2 2 0 0 2 2 2 0 Surfeit locus protein 6 CIAPIN1 PF05093.13 EEQ41063.1 - 3.6e-41 139.7 3.9 7.6e-41 138.7 3.9 1.6 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EEQ41063.1 - 1.1e-33 116.3 0.0 2.1e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus DUF2703 PF10865.8 EEQ41063.1 - 0.17 12.1 2.9 0.3 11.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) Hid1 PF12722.7 EEQ41064.1 - 2.8 5.9 12.1 3.4 5.7 12.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Paramyxo_ncap PF00973.19 EEQ41064.1 - 5.7 5.7 5.6 8 5.3 5.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ALMT PF11744.8 EEQ41064.1 - 8.5 5.1 6.3 12 4.6 6.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter COG2 PF06148.11 EEQ41065.1 - 1.3e-17 64.1 1.5 2.1e-17 63.5 1.5 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EEQ41065.1 - 0.044 13.9 0.5 0.14 12.3 0.1 2.1 2 1 0 2 2 2 0 Vps51/Vps67 CHCH PF06747.13 EEQ41066.1 - 0.012 15.7 10.9 0.053 13.7 4.5 2.5 2 0 0 2 2 2 0 CHCH domain HALZ PF02183.18 EEQ41066.1 - 0.044 14.0 2.2 0.071 13.3 0.3 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Colipase-like PF15083.6 EEQ41066.1 - 0.13 12.4 5.5 0.23 11.6 5.5 1.3 1 0 0 1 1 1 0 Colipase-like COX6B PF02297.17 EEQ41066.1 - 2 8.7 10.1 3.9 7.8 4.1 2.3 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EEQ41066.1 - 6.3 6.9 7.5 0.8 9.8 2.0 2.3 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Nup54 PF13874.6 EEQ41067.1 - 6.2e-37 126.8 0.6 1.1e-36 126.0 0.1 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EEQ41067.1 - 5.1e-18 65.7 203.1 8.6e-09 36.1 31.8 5.4 1 1 5 6 6 6 6 Nucleoporin FG repeat region FISNA PF14484.6 EEQ41067.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 Fish-specific NACHT associated domain LBR_tudor PF09465.10 EEQ41067.1 - 0.18 11.7 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain HA2 PF04408.23 EEQ41069.1 - 5.1e-22 78.2 0.1 7e-21 74.5 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EEQ41069.1 - 4.6e-16 59.0 0.1 2.2e-15 56.8 0.0 2.3 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EEQ41069.1 - 2.7e-15 56.7 0.0 7.9e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EEQ41069.1 - 4.2e-09 36.4 0.0 1e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EEQ41069.1 - 3.9e-06 27.2 0.0 1.3e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EEQ41069.1 - 0.00013 21.3 0.0 0.00034 20.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EEQ41069.1 - 0.0018 17.4 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EEQ41069.1 - 0.0094 16.3 0.0 0.062 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 EEQ41069.1 - 0.017 14.6 0.0 0.041 13.3 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 EEQ41069.1 - 0.036 13.8 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EEQ41069.1 - 0.046 13.5 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EEQ41069.1 - 0.049 14.0 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EEQ41069.1 - 0.053 14.0 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EEQ41069.1 - 0.067 13.2 0.3 4.2 7.4 0.3 3.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EEQ41069.1 - 0.09 12.7 0.8 0.34 10.8 0.0 2.3 3 0 0 3 3 3 0 NACHT domain SRP54 PF00448.22 EEQ41069.1 - 0.096 12.3 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EEQ41069.1 - 1 9.8 0.0 1 9.8 0.0 3.2 3 1 0 3 3 1 0 AAA domain Pantoate_ligase PF02569.15 EEQ41070.1 - 1.1e-94 316.5 0.0 1.3e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-grasp_2 PF08442.10 EEQ41070.1 - 0.05 13.2 0.0 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Abhydrolase_6 PF12697.7 EEQ41071.1 - 6.6e-16 59.6 0.0 8.2e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ41071.1 - 2.8e-05 23.5 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ41071.1 - 0.00049 19.8 0.0 0.069 12.8 0.0 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EEQ41071.1 - 0.063 12.9 0.0 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.21 EEQ41071.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SRP40_C PF05022.12 EEQ41072.1 - 1.5e-23 83.4 4.5 2.3e-23 82.8 2.7 2.2 2 0 0 2 2 2 1 SRP40, C-terminal domain Ada_Zn_binding PF02805.16 EEQ41073.1 - 2.7e-29 101.0 2.7 4e-29 100.4 2.7 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 EEQ41073.1 - 0.00011 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 EEQ41073.1 - 0.0042 17.3 0.1 0.0071 16.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain ERCC3_RAD25_C PF16203.5 EEQ41074.1 - 5.2e-126 418.9 0.9 9.3e-126 418.1 0.9 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EEQ41074.1 - 6.2e-36 123.3 0.1 1.8e-35 121.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EEQ41074.1 - 1.8e-15 57.4 0.0 3.4e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EEQ41074.1 - 3.1e-12 46.8 0.1 7e-12 45.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EEQ41074.1 - 1.2e-09 37.4 0.0 1.4e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EEQ41074.1 - 7.1e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1681 PF07933.14 EEQ41075.1 - 0.00019 21.2 0.0 0.061 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1681) Ribosomal_S21 PF01165.20 EEQ41076.1 - 2.6e-09 36.6 2.2 4.6e-09 35.9 2.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Gyro_capsid PF04162.12 EEQ41076.1 - 0.8 8.1 7.6 6 5.2 6.6 2.0 1 1 1 2 2 2 0 Gyrovirus capsid protein (VP1) NTF2 PF02136.20 EEQ41077.1 - 8.3e-15 55.4 0.2 8.3e-15 55.4 0.2 2.0 3 0 0 3 3 3 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EEQ41077.1 - 0.0024 17.6 0.2 0.0049 16.7 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3739 PF12545.8 EEQ41077.1 - 0.034 14.6 2.2 0.47 11.0 0.1 2.7 2 0 0 2 2 2 0 Filamentous haemagglutinin family outer membrane protein RR_TM4-6 PF06459.12 EEQ41077.1 - 1.2 8.9 19.2 0.36 10.6 15.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 EEQ41077.1 - 1.5 7.0 12.4 2.3 6.4 12.4 1.2 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 EEQ41077.1 - 3.1 6.7 10.0 6.2 5.7 10.0 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 EEQ41077.1 - 7 4.6 13.7 11 4.0 13.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UQ_con PF00179.26 EEQ41078.1 - 6.3e-46 155.5 0.0 8e-46 155.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EEQ41078.1 - 3.4e-18 65.2 0.1 5.3e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EEQ41078.1 - 0.004 16.8 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EEQ41078.1 - 0.041 14.2 0.2 0.075 13.3 0.2 1.6 1 1 0 1 1 1 0 RWD domain UBA PF00627.31 EEQ41078.1 - 0.18 11.8 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain GN3L_Grn1 PF08701.11 EEQ41078.1 - 0.24 11.5 0.4 0.6 10.3 0.4 1.6 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase Not1 PF04054.15 EEQ41079.1 - 7.8e-122 406.7 0.5 2.1e-121 405.3 0.5 1.7 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.7 EEQ41079.1 - 1.6e-09 37.9 0.8 1.6e-09 37.9 0.8 2.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) DUF4685 PF15737.5 EEQ41079.1 - 0.017 15.5 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4685) CNOT1_CAF1_bind PF16415.5 EEQ41080.1 - 3.8e-89 297.9 1.9 1.1e-88 296.4 1.3 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_HEAT_N PF16419.5 EEQ41080.1 - 1.2e-74 250.9 2.1 6e-74 248.6 2.1 2.3 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_TTP_bind PF16417.5 EEQ41080.1 - 2.7e-48 163.7 1.6 2.7e-48 163.7 1.6 2.3 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EEQ41080.1 - 3.1e-19 69.5 3.6 3.1e-19 69.5 3.6 2.6 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat TauD PF02668.16 EEQ41081.1 - 3.4e-55 187.7 0.4 4.3e-55 187.4 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RabGAP-TBC PF00566.18 EEQ41082.1 - 3e-37 128.4 3.8 3e-37 128.4 3.8 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain NFACT-R_1 PF05670.13 EEQ41083.1 - 2.1e-37 128.1 0.1 3.5e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain BslA PF17735.1 EEQ41083.1 - 0.037 14.0 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Biofilm surface layer A COX6B PF02297.17 EEQ41085.1 - 1.6e-17 63.5 3.4 1.9e-17 63.3 3.4 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 EEQ41085.1 - 0.0015 18.5 1.2 0.0025 17.8 1.2 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Somatostatin PF03002.15 EEQ41085.1 - 0.97 9.4 6.7 2 8.4 6.7 1.6 1 1 0 1 1 1 0 Somatostatin/Cortistatin family Alba PF01918.21 EEQ41086.1 - 2.3e-08 33.8 0.2 4e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 Alba CdhD PF03599.16 EEQ41086.1 - 0.051 12.3 0.1 0.063 12.0 0.1 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit FTR1 PF03239.14 EEQ41088.1 - 7.5e-93 311.1 6.3 9e-93 310.8 6.3 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family H_PPase PF03030.16 EEQ41088.1 - 0.0025 16.5 1.8 0.022 13.4 0.2 2.1 1 1 1 2 2 2 1 Inorganic H+ pyrophosphatase ESSS PF10183.9 EEQ41088.1 - 0.12 12.6 0.0 0.39 10.9 0.0 1.9 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4199 PF13858.6 EEQ41088.1 - 4.7 7.6 14.3 0.15 12.5 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Yip1 PF04893.17 EEQ41088.1 - 6.7 6.4 21.9 0.11 12.2 2.9 2.9 2 1 0 2 2 2 0 Yip1 domain Sec5 PF15469.6 EEQ41090.1 - 2.2e-49 167.9 11.3 2.2e-49 167.9 11.3 3.3 4 0 0 4 4 4 1 Exocyst complex component Sec5 RICH PF05062.12 EEQ41090.1 - 0.04 14.3 4.2 0.15 12.4 0.7 3.7 3 0 0 3 3 3 0 RICH domain Vps51 PF08700.11 EEQ41090.1 - 0.044 13.8 0.2 0.044 13.8 0.2 3.9 4 1 0 4 4 4 0 Vps51/Vps67 COG2 PF06148.11 EEQ41090.1 - 0.061 13.4 0.1 0.061 13.4 0.1 3.9 4 0 0 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2115 PF09888.9 EEQ41090.1 - 6.8 7.2 8.1 5 7.6 0.2 3.6 2 1 2 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2115) Myb_DNA-binding PF00249.31 EEQ41091.1 - 7.5e-20 70.9 10.1 3.4e-10 39.9 0.4 3.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ41091.1 - 8.5e-19 67.6 0.9 1.7e-13 50.6 0.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EEQ41091.1 - 0.0081 16.5 8.6 0.012 16.0 2.0 3.4 2 2 0 2 2 2 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.9 EEQ41091.1 - 1.2 9.5 7.5 13 6.2 0.6 3.5 1 1 2 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Nop14 PF04147.12 EEQ41091.1 - 2.1 6.4 17.8 2.9 6.0 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family TMEM51 PF15345.6 EEQ41092.1 - 0.31 10.8 7.1 0.27 11.0 5.1 1.9 1 1 0 1 1 1 0 Transmembrane protein 51 TMCO5 PF14992.6 EEQ41092.1 - 2.9 7.4 21.5 0.21 11.1 8.6 2.4 1 1 1 2 2 2 0 TMCO5 family DUF4407 PF14362.6 EEQ41092.1 - 3.8 6.8 12.1 6.1 6.1 12.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.15 EEQ41092.1 - 7.1 6.8 12.5 0.38 10.9 3.6 3.0 2 1 0 2 2 2 0 Basic region leucine zipper Importin_rep_5 PF18816.1 EEQ41093.1 - 0.099 13.0 0.1 0.33 11.3 0.1 1.9 1 0 0 1 1 1 0 Importin repeat Rep-A_N PF04057.12 EEQ41093.1 - 0.2 11.7 1.9 1.2 9.2 1.5 2.5 2 0 0 2 2 2 0 Replication factor-A protein 1, N-terminal domain Bacteriocin_IIi PF11758.8 EEQ41095.1 - 0.034 14.0 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin SPACA9 PF15120.6 EEQ41095.1 - 0.64 9.8 3.1 0.88 9.3 0.1 2.7 3 1 0 3 3 3 0 Sperm acrosome-associated protein 9 Cu-oxidase_3 PF07732.15 EEQ41096.1 - 5.6e-25 87.7 0.0 6.7e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EEQ41097.1 - 8e-47 158.4 2.6 9.7e-45 151.7 1.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EEQ41097.1 - 3.6e-31 108.4 0.8 4.6e-30 104.8 0.1 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 EEQ41097.1 - 6.7e-11 42.2 1.5 2e-08 34.3 0.1 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 EEQ41097.1 - 0.12 12.5 0.0 7 6.8 0.0 2.5 2 0 0 2 2 2 0 Cupredoxin-like domain Snf7 PF03357.21 EEQ41098.1 - 4.9e-29 101.1 26.6 1.9e-28 99.2 22.9 2.0 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 EEQ41098.1 - 0.0007 19.6 6.8 0.0011 18.9 6.8 1.5 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Uds1 PF15456.6 EEQ41098.1 - 0.003 17.7 0.3 0.003 17.7 0.3 2.3 2 0 0 2 2 2 1 Up-regulated During Septation Corona_S2 PF01601.16 EEQ41098.1 - 0.64 8.4 5.1 0.71 8.3 5.1 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF4407 PF14362.6 EEQ41098.1 - 0.66 9.3 10.5 0.91 8.8 10.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 EEQ41098.1 - 0.76 10.0 16.1 0.073 13.3 9.8 2.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain RecC_C PF17946.1 EEQ41098.1 - 0.84 9.4 5.4 2.1 8.1 0.2 2.3 2 1 0 2 2 2 0 RecC C-terminal domain Alkyl_sulf_dimr PF14863.6 EEQ41098.1 - 2.5 8.6 5.2 1.8 9.0 3.2 1.7 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation Josephin PF02099.17 EEQ41098.1 - 3.1 7.9 10.1 2.9 8.0 3.4 2.2 1 1 1 2 2 2 0 Josephin YlqD PF11068.8 EEQ41098.1 - 5.7 7.3 21.4 9.9 6.6 13.1 2.2 1 1 1 2 2 2 0 YlqD protein APS_kinase PF01583.20 EEQ41099.1 - 5.4e-72 240.9 0.0 6.5e-72 240.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EEQ41099.1 - 6.9e-05 23.0 0.0 0.00014 22.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 EEQ41099.1 - 0.00022 20.8 0.0 0.00031 20.3 0.0 1.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EEQ41099.1 - 0.0018 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EEQ41099.1 - 0.0024 18.4 0.0 0.02 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EEQ41099.1 - 0.004 16.9 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EEQ41099.1 - 0.0068 16.9 0.3 0.0089 16.5 0.3 1.5 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 EEQ41099.1 - 0.023 13.9 0.3 0.07 12.3 0.1 1.7 1 1 0 2 2 2 0 G-protein alpha subunit CbiA PF01656.23 EEQ41099.1 - 0.058 13.5 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 EEQ41099.1 - 0.068 13.6 0.0 0.082 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 EEQ41099.1 - 0.099 12.5 0.1 0.86 9.4 0.1 2.1 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 EEQ41099.1 - 0.1 13.1 0.0 0.16 12.5 0.0 1.4 1 1 0 1 1 1 0 ABC transporter SAICAR_synt PF01259.18 EEQ41100.1 - 6.3e-104 347.0 0.0 7.3e-104 346.8 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Pkinase PF00069.25 EEQ41101.1 - 1.3e-57 195.2 0.3 1.5e-33 116.3 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41101.1 - 6.3e-34 117.4 0.0 2.6e-21 76.1 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ41101.1 - 8.4e-06 24.8 0.0 8.4e-06 24.8 0.0 3.3 3 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EEQ41101.1 - 0.025 14.5 0.4 0.13 12.2 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family PIN_8 PF18476.1 EEQ41101.1 - 2.1 8.1 18.9 2.5 7.9 0.4 2.3 1 1 1 2 2 2 0 PIN like domain Flo11 PF10182.9 EEQ41102.1 - 4.4e-40 137.3 1.5 4.4e-40 137.3 1.5 2.6 2 0 0 2 2 2 1 Flo11 domain GLEYA PF10528.9 EEQ41103.1 - 2.3e-14 53.6 0.2 2.3e-14 53.6 0.2 3.8 3 1 1 4 4 4 1 GLEYA domain PA14 PF07691.12 EEQ41103.1 - 1.4e-08 34.7 2.8 1.8e-08 34.3 0.1 2.7 3 0 0 3 3 3 1 PA14 domain Hyphal_reg_CWP PF11765.8 EEQ41105.1 - 2.9e-71 240.1 10.7 6e-71 239.1 10.7 1.5 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Endonuc-FokI_C PF09254.11 EEQ41105.1 - 0.0029 16.9 9.4 64 2.7 0.0 8.9 2 2 9 12 12 12 0 Restriction endonuclease FokI, C terminal Ribosomal_S27e PF01667.17 EEQ41105.1 - 0.78 9.5 74.7 12 5.7 0.1 15.0 17 0 0 17 17 17 0 Ribosomal protein S27 Flo11 PF10182.9 EEQ41106.1 - 4.7e-42 143.7 1.7 1.2e-41 142.4 1.7 1.7 1 0 0 1 1 1 1 Flo11 domain FAD_binding_7 PF03441.14 EEQ41107.1 - 9.3e-73 244.0 0.1 1.7e-72 243.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EEQ41107.1 - 1.9e-31 109.3 0.1 3.7e-31 108.4 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase BRE PF06113.12 EEQ41107.1 - 0.0095 14.8 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 2 Brain and reproductive organ-expressed protein (BRE) TAF1D PF15333.6 EEQ41107.1 - 0.029 14.1 1.2 0.061 13.1 1.2 1.5 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D F-box-like PF12937.7 EEQ41108.1 - 0.022 14.6 0.3 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 F-box-like zf-C2H2_4 PF13894.6 EEQ41109.1 - 2.6e-05 24.7 13.6 0.029 15.2 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EEQ41109.1 - 6.8e-05 23.1 4.5 0.018 15.2 0.3 2.3 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 EEQ41109.1 - 0.00012 22.3 16.8 0.017 15.5 1.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EEQ41109.1 - 0.0011 19.2 0.3 1.5 9.2 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EEQ41109.1 - 0.045 14.2 0.6 0.045 14.2 0.6 3.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-met PF12874.7 EEQ41109.1 - 0.067 13.6 1.1 1.6 9.2 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Filo_VP35 PF02097.15 EEQ41109.1 - 0.15 11.1 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Seipin PF06775.14 EEQ41110.1 - 4.2e-07 30.3 2.6 0.0065 16.6 0.4 2.2 2 0 0 2 2 2 2 Putative adipose-regulatory protein (Seipin) Asp PF00026.23 EEQ41111.1 - 4e-17 62.6 0.0 8.6e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Endosulfine PF04667.17 EEQ41111.1 - 0.18 11.9 1.9 0.67 10.1 0.0 2.5 3 0 0 3 3 3 0 cAMP-regulated phosphoprotein/endosulfine conserved region DUF1765 PF08578.10 EEQ41112.1 - 3.3e-37 127.8 9.8 7.7e-37 126.6 9.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) TMCO5 PF14992.6 EEQ41113.1 - 0.0024 17.5 5.0 0.0024 17.5 5.0 6.3 1 1 6 7 7 7 1 TMCO5 family PI3K_P85_iSH2 PF16454.5 EEQ41113.1 - 0.0025 17.5 7.2 0.0025 17.5 7.2 7.8 2 1 6 8 8 8 3 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Cep57_CLD PF14073.6 EEQ41113.1 - 0.006 16.6 19.8 0.006 16.6 19.8 7.1 1 1 6 7 7 7 2 Centrosome localisation domain of Cep57 GAS PF13851.6 EEQ41113.1 - 0.13 11.6 172.1 0.041 13.2 41.5 7.3 1 1 6 7 7 7 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EEQ41113.1 - 0.22 11.7 172.7 0.27 11.4 15.4 8.9 2 1 5 8 8 8 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EEQ41113.1 - 0.23 10.8 137.6 0.27 10.5 18.9 6.3 1 1 4 6 6 6 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 EEQ41113.1 - 3.6 7.6 187.6 0.11 12.5 18.4 8.0 2 1 8 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Choline_kinase PF01633.20 EEQ41114.1 - 1.6e-53 181.5 0.1 2.7e-53 180.7 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EEQ41114.1 - 1.6e-14 53.3 0.0 3.6e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EEQ41114.1 - 1.6e-06 28.2 0.1 2.8e-06 27.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 EEQ41116.1 - 5.9e-16 58.6 12.3 0.0028 18.5 0.3 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat KH_1 PF00013.29 EEQ41117.1 - 3.3e-20 71.7 2.5 4.8e-07 29.5 0.1 6.0 6 0 0 6 6 6 4 KH domain ELO PF01151.18 EEQ41118.1 - 5.3e-71 239.1 12.6 6.3e-71 238.8 12.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Sugar_tr PF00083.24 EEQ41119.1 - 2.8e-99 333.0 12.1 3.4e-99 332.7 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ41119.1 - 1.9e-34 119.2 38.7 4.4e-31 108.1 18.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EEQ41119.1 - 0.051 11.9 5.0 0.034 12.4 2.7 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TPR_1 PF00515.28 EEQ41120.1 - 2.2e-58 191.9 25.8 1.9e-07 30.6 0.0 11.1 11 1 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ41120.1 - 1e-53 175.1 23.0 1.8e-06 27.6 0.0 10.6 11 0 0 11 11 10 10 Tetratricopeptide repeat TPR_8 PF13181.6 EEQ41120.1 - 1.9e-39 130.6 11.9 0.00016 21.6 0.0 11.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ41120.1 - 1.6e-35 118.9 19.2 0.0001 22.4 0.2 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 EEQ41120.1 - 1.1e-32 111.4 22.7 2.9e-06 26.8 0.0 9.7 5 3 4 9 9 9 7 TPR repeat TPR_14 PF13428.6 EEQ41120.1 - 1.4e-30 103.4 12.4 3.5e-05 24.3 0.1 10.3 3 2 7 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ41120.1 - 2.2e-29 101.8 8.5 1.9e-05 25.2 0.0 6.8 5 1 0 6 6 6 6 Tetratricopeptide repeat TPR_19 PF14559.6 EEQ41120.1 - 9.9e-27 93.3 16.4 3.2e-05 24.3 0.3 7.5 6 2 1 7 7 6 6 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ41120.1 - 2e-24 85.5 8.7 6.7e-05 23.0 0.1 7.3 3 2 2 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.6 EEQ41120.1 - 7.5e-24 83.8 22.6 0.00012 22.3 2.7 8.0 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EEQ41120.1 - 2e-22 77.5 10.5 0.0015 18.4 0.1 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 EEQ41120.1 - 1.5e-18 66.1 10.0 0.0058 17.2 0.0 9.3 9 0 0 9 9 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EEQ41120.1 - 2.1e-11 43.9 6.8 1.5e-05 25.1 0.1 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 EEQ41120.1 - 4.6e-10 39.4 1.2 0.0006 19.3 0.3 4.2 3 1 2 5 5 5 2 MalT-like TPR region TPR_15 PF13429.6 EEQ41120.1 - 5e-10 39.0 8.5 0.0042 16.3 0.0 5.1 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_21 PF09976.9 EEQ41120.1 - 1.2e-06 28.4 6.4 0.0035 17.1 3.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat-like domain ChAPs PF09295.10 EEQ41120.1 - 1.1e-05 24.6 0.7 0.19 10.7 0.1 3.0 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EEQ41120.1 - 1.1e-05 25.1 18.8 0.21 11.5 0.4 8.2 7 1 1 8 8 8 1 Tetratricopeptide repeat NARP1 PF12569.8 EEQ41120.1 - 1.2e-05 24.4 3.7 0.78 8.6 0.3 4.4 4 1 1 5 5 5 2 NMDA receptor-regulated protein 1 PPTA PF01239.22 EEQ41120.1 - 0.082 12.7 0.7 0.42 10.4 0.1 2.6 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat SNAP PF14938.6 EEQ41120.1 - 0.63 9.4 13.6 0.63 9.4 0.8 4.5 3 2 1 4 4 4 0 Soluble NSF attachment protein, SNAP BTAD PF03704.17 EEQ41120.1 - 0.92 9.9 7.2 12 6.3 0.2 3.5 2 2 0 3 3 3 0 Bacterial transcriptional activator domain TOM20_plant PF06552.12 EEQ41120.1 - 1.4 8.6 8.0 15 5.3 0.1 4.1 4 2 2 6 6 5 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_20 PF14561.6 EEQ41120.1 - 2.4 8.6 10.1 4.8 7.6 0.0 4.6 6 1 1 7 7 3 0 Tetratricopeptide repeat Utp14 PF04615.13 EEQ41122.1 - 0.015 13.9 20.3 0.017 13.8 20.3 1.2 1 0 0 1 1 1 0 Utp14 protein GREB1 PF15782.5 EEQ41122.1 - 0.059 10.5 34.6 0.061 10.4 34.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 EEQ41122.1 - 0.089 11.8 9.6 0.12 11.4 9.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 SDA1 PF05285.12 EEQ41122.1 - 0.63 9.4 20.0 0.77 9.1 20.0 1.2 1 0 0 1 1 1 0 SDA1 EphA2_TM PF14575.6 EEQ41122.1 - 2.8 8.9 5.6 26 5.8 5.6 2.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RINGv PF12906.7 EEQ41124.1 - 0.00029 20.9 0.3 0.00067 19.7 0.3 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EEQ41124.1 - 0.017 15.3 1.4 0.029 14.5 0.1 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain MspA PF09203.11 EEQ41125.1 - 0.00021 21.2 21.0 0.51 10.2 21.0 2.5 1 1 0 1 1 1 1 MspA PorP_SprF PF11751.8 EEQ41125.1 - 0.002 17.7 1.4 0.0067 16.0 1.4 1.8 1 1 0 1 1 1 1 Type IX secretion system membrane protein PorP/SprF DUF481 PF04338.12 EEQ41125.1 - 0.43 10.6 1.9 2.4 8.1 1.9 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF481 DUF1943 PF09172.11 EEQ41125.1 - 0.43 9.8 40.9 1.8e+04 -7.9 40.9 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1943) CEL_III_C PF18054.1 EEQ41125.1 - 8 6.5 33.9 1.8e+04 -8.8 33.9 3.5 1 1 0 1 1 1 0 CEL-III C-terminal NUDIX PF00293.28 EEQ41126.1 - 1e-12 48.3 0.0 2.1e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain EnY2 PF10163.9 EEQ41127.1 - 2.2e-27 95.2 0.1 2.5e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 Oxidored_q6 PF01058.22 EEQ41128.1 - 3.2e-22 78.8 0.1 4.4e-22 78.3 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Histone PF00125.24 EEQ41130.1 - 1.9e-51 173.9 2.4 2.1e-51 173.7 2.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EEQ41130.1 - 3.5e-06 27.3 0.0 5.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EEQ41130.1 - 2.6e-05 24.3 0.4 4.3e-05 23.6 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EEQ41130.1 - 0.00013 22.6 1.2 0.00015 22.4 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EEQ41130.1 - 0.0012 19.0 0.8 0.0017 18.6 0.1 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EEQ41130.1 - 0.023 14.8 0.3 0.035 14.2 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.22 EEQ41131.1 - 6.1e-42 141.3 0.0 4.3e-16 58.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EEQ41131.1 - 0.0012 18.8 0.0 0.0048 16.9 0.0 2.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EEQ41131.1 - 0.0026 17.3 0.0 0.051 13.2 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EEQ41131.1 - 0.0032 17.5 0.1 0.017 15.1 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 EEQ41131.1 - 0.0056 16.8 0.0 0.081 13.1 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 EEQ41131.1 - 0.11 12.4 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Occluded RNA-recognition motif MAS20 PF02064.15 EEQ41131.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.6 3 0 0 3 3 3 0 MAS20 protein import receptor LRR_4 PF12799.7 EEQ41132.1 - 8.3e-24 83.3 66.6 1.6e-06 28.3 3.8 8.7 7 2 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EEQ41132.1 - 1.4e-16 60.0 61.8 4.6e-05 23.1 10.7 8.0 3 1 7 10 10 10 8 Leucine rich repeat LRR_9 PF14580.6 EEQ41132.1 - 1.3e-07 31.3 22.7 0.0022 17.6 6.4 5.1 2 1 3 6 6 6 5 Leucine-rich repeat EFhand_Ca_insen PF08726.10 EEQ41132.1 - 0.12 12.5 0.5 0.51 10.5 0.5 2.2 1 0 0 1 1 1 0 Ca2+ insensitive EF hand HRI1 PF16815.5 EEQ41133.1 - 2.3e-44 151.8 1.1 2.6e-44 151.6 1.1 1.0 1 0 0 1 1 1 1 Protein HRI1 Cornichon PF03311.14 EEQ41134.1 - 6.9e-44 149.1 4.0 7.8e-44 148.9 4.0 1.0 1 0 0 1 1 1 1 Cornichon protein DASH_Dad2 PF08654.10 EEQ41136.1 - 0.053 14.0 0.2 0.095 13.1 0.1 1.4 1 1 0 1 1 1 0 DASH complex subunit Dad2 DUF5466 PF17554.2 EEQ41136.1 - 0.37 11.0 4.0 0.25 11.6 1.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5466) Peptidase_S49_N PF08496.10 EEQ41136.1 - 0.79 9.8 3.0 0.71 9.9 1.8 1.5 1 1 0 1 1 1 0 Peptidase family S49 N-terminal AsnA PF03590.15 EEQ41137.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Aspartate-ammonia ligase Ribosomal_L7Ae PF01248.26 EEQ41138.1 - 3.5e-25 87.6 1.3 4.9e-25 87.1 1.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family KNOX2 PF03791.13 EEQ41138.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 KNOX2 domain NTP_transf_3 PF12804.7 EEQ41138.1 - 0.038 14.4 0.2 0.05 14.0 0.2 1.4 1 1 0 1 1 1 0 MobA-like NTP transferase domain SBD_N PF07005.11 EEQ41138.1 - 0.072 12.8 0.3 0.088 12.5 0.3 1.2 1 0 0 1 1 1 0 Sugar-binding N-terminal domain GDI PF00996.18 EEQ41139.1 - 4.6e-43 147.3 0.6 1.4e-42 145.8 0.1 1.8 2 1 0 2 2 2 1 GDP dissociation inhibitor FAD_binding_3 PF01494.19 EEQ41139.1 - 0.014 14.6 0.0 0.04 13.2 0.0 1.8 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.6 EEQ41139.1 - 0.03 14.5 0.0 0.077 13.2 0.0 1.8 1 1 0 1 1 1 0 NAD(P)-binding Rossmann-like domain PI3Ka PF00613.20 EEQ41139.1 - 0.08 12.3 0.5 11 5.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) NAD_binding_7 PF13241.6 EEQ41140.1 - 2e-30 105.3 0.0 3.4e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EEQ41140.1 - 3e-15 55.6 0.1 7.7e-15 54.3 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EEQ41140.1 - 7.7e-13 47.6 0.1 7.7e-13 47.6 0.1 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein central Pyr_redox PF00070.27 EEQ41140.1 - 0.018 15.6 0.0 0.048 14.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EEQ41140.1 - 0.02 14.2 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ41140.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EEQ41140.1 - 0.12 11.7 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EEQ41140.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 EEQ41140.1 - 0.19 12.0 0.0 0.47 10.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Aldedh PF00171.22 EEQ41141.1 - 7.9e-23 80.7 1.8 2.4e-17 62.6 0.7 2.5 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF1542 PF07564.11 EEQ41141.1 - 0.031 14.4 2.8 0.031 14.4 2.8 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) URO-D PF01208.17 EEQ41141.1 - 0.09 11.9 0.0 0.19 10.8 0.0 1.5 1 1 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) PCRF PF03462.18 EEQ41141.1 - 1.5 8.7 3.4 1.5 8.7 0.2 2.2 2 0 0 2 2 2 0 PCRF domain PhoLip_ATPase_C PF16212.5 EEQ41142.1 - 5.7e-54 183.5 11.3 5.7e-54 183.5 11.3 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EEQ41142.1 - 8.6e-26 89.4 7.5 4.1e-25 87.2 6.1 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EEQ41142.1 - 3.5e-12 47.1 0.7 1.3e-06 28.9 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EEQ41142.1 - 2.1e-11 43.7 0.0 1.2e-10 41.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EEQ41142.1 - 1.5e-05 24.6 0.0 3.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EEQ41142.1 - 0.0004 20.2 0.2 0.0093 15.7 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IF-2B PF01008.17 EEQ41143.1 - 1.7e-78 263.7 2.9 1.1e-39 136.3 0.1 2.5 3 0 0 3 3 3 2 Initiation factor 2 subunit family EFTUD2 PF16004.5 EEQ41143.1 - 1.5 9.4 15.3 2.2 8.9 5.9 2.3 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF4228 PF14009.6 EEQ41143.1 - 2.8 8.3 7.9 13 6.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) Dsh_C PF12316.8 EEQ41143.1 - 7.1 7.0 7.6 15 6.0 3.2 2.3 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Ecm29 PF13001.7 EEQ41144.1 - 3.1e-136 455.0 2.2 3.1e-136 455.0 2.2 3.6 4 0 0 4 4 4 1 Proteasome stabiliser HEAT PF02985.22 EEQ41144.1 - 1.9e-11 43.2 2.5 0.094 13.0 0.0 7.0 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EEQ41144.1 - 3e-09 37.4 0.0 0.0078 16.8 0.0 5.6 7 0 0 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EEQ41144.1 - 2.7e-05 24.5 4.0 0.96 9.9 0.0 6.4 6 1 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 EEQ41144.1 - 0.00034 21.0 5.3 0.053 14.0 0.5 5.7 5 1 1 6 6 6 1 HEAT-like repeat Viral_DNA_bi PF02236.17 EEQ41144.1 - 0.0058 16.8 0.0 4.6 7.5 0.0 3.1 2 0 0 2 2 2 2 Viral DNA-binding protein, all alpha domain RTP1_C1 PF10363.9 EEQ41144.1 - 0.033 14.4 6.7 22 5.3 0.1 5.2 6 0 0 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 AIB PF15334.6 EEQ41144.1 - 0.044 13.1 0.1 0.084 12.2 0.1 1.4 1 0 0 1 1 1 0 Aurora kinase A and ninein interacting protein Nop52 PF05997.12 EEQ41144.1 - 0.72 9.6 6.6 1.4 8.6 0.3 3.6 3 0 0 3 3 3 0 Nucleolar protein,Nop52 ubiquitin PF00240.23 EEQ41145.1 - 4.6e-168 545.3 27.6 4.7e-33 112.7 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 EEQ41145.1 - 4.3e-79 260.4 28.3 2.9e-15 55.9 0.7 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EEQ41145.1 - 8.3e-28 96.7 14.8 0.00061 20.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 EEQ41145.1 - 5.4e-20 71.1 5.5 0.038 13.9 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EEQ41145.1 - 2.6e-18 66.2 11.7 0.041 14.2 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EEQ41145.1 - 2.2e-17 63.2 4.7 0.18 12.0 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EEQ41145.1 - 7.1e-16 58.7 2.8 0.49 11.0 0.0 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 EEQ41145.1 - 3.1e-08 33.2 1.3 2.6 7.3 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 EEQ41145.1 - 9.8e-08 31.9 32.0 22 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 EEQ41145.1 - 2.4e-07 31.0 0.0 40 4.7 0.0 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 EEQ41145.1 - 5.3e-07 29.7 5.3 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 EEQ41145.1 - 1.6e-06 27.8 7.7 13 5.7 0.0 5.3 5 0 0 5 5 5 0 ACT domain Big_7 PF17957.1 EEQ41145.1 - 2.4e-06 28.2 0.6 71 4.3 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 EEQ41145.1 - 1.4e-05 25.2 7.4 9.9 6.3 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 EEQ41145.1 - 3e-05 23.5 0.0 32 3.8 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) DUF493 PF04359.14 EEQ41145.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) YcgR_2 PF12945.7 EEQ41145.1 - 0.00041 20.4 9.7 38 4.5 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ORF11CD3 PF10549.9 EEQ41145.1 - 0.00068 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ACT_4 PF13291.6 EEQ41145.1 - 0.0018 18.8 2.5 1.9e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 ACT domain Baculo_p48 PF04878.13 EEQ41145.1 - 0.024 13.6 0.0 84 1.9 0.0 3.8 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 EEQ41145.1 - 0.14 12.3 9.2 1.4e+02 2.7 0.1 5.0 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 EEQ41145.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif HAMP_N3 PF18575.1 EEQ41145.1 - 0.23 11.1 3.3 2.6e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 HAMP N-terminal domain 3 Myosin_N PF02736.19 EEQ41145.1 - 0.28 11.0 9.4 1.4e+02 2.4 0.0 6.1 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 EEQ41145.1 - 5.6 6.8 13.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain MFS_1 PF07690.16 EEQ41148.1 - 1.1e-14 54.2 11.1 1.1e-14 54.2 11.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Ferric_reduct PF01794.19 EEQ41148.1 - 0.022 14.9 4.1 0.13 12.4 0.7 2.9 2 1 0 3 3 3 0 Ferric reductase like transmembrane component Phage_holin_3_6 PF07332.11 EEQ41148.1 - 0.025 14.6 0.0 0.025 14.6 0.0 3.6 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III ATP1G1_PLM_MAT8 PF02038.16 EEQ41148.1 - 0.052 13.0 0.1 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family LapA_dom PF06305.11 EEQ41148.1 - 0.66 9.8 5.7 10 6.0 0.0 3.4 2 1 2 4 4 4 0 Lipopolysaccharide assembly protein A domain fn3 PF00041.21 EEQ41149.1 - 0.0015 18.9 0.0 0.011 16.1 0.0 2.1 1 1 0 1 1 1 1 Fibronectin type III domain Sec34 PF04136.15 EEQ41150.1 - 0.078 12.9 0.5 0.16 11.8 0.5 1.5 1 0 0 1 1 1 0 Sec34-like family DUF4200 PF13863.6 EEQ41150.1 - 0.13 12.7 0.4 0.22 11.9 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4061 PF13270.6 EEQ41150.1 - 0.16 12.3 0.4 0.38 11.1 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Eapp_C PF10238.9 EEQ41151.1 - 0.014 15.4 1.8 0.02 15.0 1.8 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Connexin PF00029.19 EEQ41151.1 - 0.41 10.4 1.3 0.44 10.3 1.3 1.2 1 0 0 1 1 1 0 Connexin Beta_elim_lyase PF01212.21 EEQ41152.1 - 6.4e-77 258.7 0.0 8e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EEQ41152.1 - 2.7e-05 23.5 0.0 5.1e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EEQ41152.1 - 5.8e-05 22.6 0.1 0.0037 16.6 0.0 2.4 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family TCR PF03638.15 EEQ41152.1 - 0.13 12.5 0.4 0.3 11.4 0.4 1.5 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain MFS_1 PF07690.16 EEQ41154.1 - 3.4e-33 115.0 24.0 3.4e-33 115.0 24.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ41154.1 - 1.9e-11 43.5 23.9 4.4e-11 42.3 23.9 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Alk_phosphatase PF00245.20 EEQ41155.1 - 1.2e-115 386.9 0.0 1.4e-115 386.6 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EEQ41155.1 - 4.7e-06 26.2 0.0 1.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily OCD_Mu_crystall PF02423.15 EEQ41156.1 - 1.1e-19 70.6 0.0 1.4e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EEQ41156.1 - 0.00063 19.8 0.1 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Aconitase PF00330.20 EEQ41158.1 - 4.4e-161 537.0 0.0 5.5e-161 536.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EEQ41158.1 - 1.6e-43 148.1 0.0 3.4e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Cullin PF00888.22 EEQ41159.1 - 2e-155 518.9 10.5 2e-155 518.9 10.5 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EEQ41159.1 - 3e-27 94.4 3.6 9.1e-27 92.9 3.6 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain SBP_bac_8 PF13416.6 EEQ41159.1 - 0.11 12.3 0.6 0.21 11.4 0.4 1.6 1 1 0 1 1 1 0 Bacterial extracellular solute-binding protein YmgB PF10798.8 EEQ41159.1 - 1.5 8.7 9.4 0.39 10.6 0.4 3.6 4 0 0 4 4 4 0 Biofilm development protein YmgB/AriR SBE2 PF17076.5 EEQ41160.1 - 5.1e-08 31.7 22.7 5.1e-08 31.7 22.7 1.9 2 0 0 2 2 2 1 SBE2, cell-wall formation NRDE-2 PF08424.10 EEQ41161.1 - 6.6e-05 22.2 19.9 0.00079 18.6 0.2 5.5 2 2 2 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EEQ41161.1 - 6.8e-05 23.4 0.5 84 4.4 0.0 6.7 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 EEQ41161.1 - 0.00013 22.1 3.9 0.019 15.3 0.8 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF410 PF04190.13 EEQ41161.1 - 0.00088 19.1 1.8 0.032 14.1 0.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF410) TPR_2 PF07719.17 EEQ41161.1 - 0.0017 18.3 1.9 9.8 6.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EEQ41161.1 - 0.0059 16.6 25.4 0.096 12.7 0.7 7.0 6 3 1 7 7 7 2 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 EEQ41161.1 - 0.015 15.8 0.1 10 6.7 0.0 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF4472 PF14739.6 EEQ41161.1 - 0.041 14.6 0.2 0.22 12.3 0.2 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) TipAS PF07739.13 EEQ41161.1 - 0.048 14.2 0.3 17 6.0 0.0 3.1 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain TPR_8 PF13181.6 EEQ41161.1 - 0.06 13.6 2.3 2.9 8.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EEQ41161.1 - 0.078 13.1 0.5 6.7 6.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2963 PF11178.8 EEQ41161.1 - 0.084 12.6 2.0 0.72 9.6 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Pkinase PF00069.25 EEQ41162.1 - 5.2e-76 255.5 0.1 1e-75 254.5 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41162.1 - 2.9e-33 115.2 0.1 7.8e-23 81.1 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EEQ41162.1 - 1.6e-07 30.9 0.1 7.2e-05 22.2 0.0 3.0 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EEQ41162.1 - 0.0078 15.6 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PIR PF00399.19 EEQ41164.1 - 7.3e-07 28.6 84.2 0.0021 17.6 4.4 7.5 7 1 0 7 7 7 6 Yeast PIR protein repeat DUF2433 PF10360.9 EEQ41165.1 - 2.9e-15 56.4 0.0 7.6e-15 55.1 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2433) Nucleoporin_C PF03177.14 EEQ41165.1 - 0.19 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Non-repetitive/WGA-negative nucleoporin C-terminal Flo11 PF10182.9 EEQ41167.1 - 3e-05 24.2 0.0 5.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Flo11 domain zf-RING_12 PF17976.1 EEQ41168.1 - 0.089 13.1 0.2 94 3.4 0.0 4.1 1 1 2 4 4 4 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.7 EEQ41170.1 - 1.6e-13 51.0 0.0 4.1e-06 27.3 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ41170.1 - 3.9e-11 43.3 4.5 2.1e-05 25.0 0.3 4.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EEQ41170.1 - 1.1e-07 32.0 0.1 4.7e-05 23.6 0.0 3.9 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.30 EEQ41170.1 - 3.7e-06 27.1 0.7 1.1 9.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EEQ41170.1 - 8.5e-05 22.7 3.4 0.012 16.0 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat MutS_V PF00488.21 EEQ41171.1 - 1.7e-67 227.1 0.0 3.1e-67 226.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_I PF01624.20 EEQ41171.1 - 1.8e-30 105.5 0.0 4.6e-30 104.2 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 EEQ41171.1 - 1.4e-29 103.7 1.3 3.5e-29 102.4 1.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 EEQ41171.1 - 2e-11 44.3 2.3 3.9e-10 40.1 0.0 2.8 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EEQ41171.1 - 1.3e-07 31.9 0.3 5.6e-07 29.8 0.3 2.2 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.6 EEQ41171.1 - 0.09 12.8 0.7 0.48 10.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EEQ41171.1 - 0.86 10.1 4.0 21 5.5 0.0 3.3 3 0 0 3 3 3 0 AAA domain APG6_N PF17675.1 EEQ41171.1 - 4.5 7.8 5.6 19 5.8 0.0 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region Abhydrolase_6 PF12697.7 EEQ41172.1 - 9.2e-15 55.8 0.0 1.4e-14 55.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EEQ41172.1 - 1.1e-12 48.2 0.0 4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ41172.1 - 4.2e-07 29.5 0.0 5.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DUF900 PF05990.12 EEQ41172.1 - 0.2 11.2 0.0 1.4 8.4 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Pmp3 PF01679.17 EEQ41173.1 - 1.8e-19 69.7 7.7 2.6e-19 69.1 7.7 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TUG-UBL1 PF11470.8 EEQ41174.1 - 2.9e-16 59.4 0.9 9.1e-16 57.8 0.9 1.9 1 0 0 1 1 1 1 TUG ubiquitin-like domain Mis12 PF05859.12 EEQ41174.1 - 0.093 12.8 1.9 0.26 11.3 1.9 1.8 1 0 0 1 1 1 0 Mis12 protein DUF3979 PF13141.6 EEQ41174.1 - 0.18 12.1 0.3 5.2 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3979) TolA_bind_tri PF16331.5 EEQ41174.1 - 0.27 11.3 7.5 0.99 9.5 5.7 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation RA PF00788.23 EEQ41174.1 - 0.44 11.2 4.0 1.9 9.2 0.0 3.1 3 1 0 3 3 3 0 Ras association (RalGDS/AF-6) domain bZIP_1 PF00170.21 EEQ41175.1 - 8.3e-09 35.4 7.9 1.9e-08 34.3 7.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EEQ41175.1 - 1.2e-07 31.7 9.7 2.3e-07 30.8 9.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EEQ41175.1 - 0.0081 16.7 2.2 0.0081 16.7 2.2 1.7 2 0 0 2 2 2 1 bZIP Maf transcription factor HeH PF12949.7 EEQ41175.1 - 0.055 13.2 0.0 0.27 11.0 0.0 2.2 2 0 0 2 2 2 0 HeH/LEM domain Phlebovirus_NSM PF07246.11 EEQ41175.1 - 0.093 12.1 0.9 0.12 11.7 0.9 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M VGPC1_C PF16799.5 EEQ41175.1 - 0.38 10.8 3.7 1 9.4 2.5 2.1 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 RRM_1 PF00076.22 EEQ41176.1 - 5.9e-21 74.1 0.4 1.2e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ41176.1 - 3.8e-10 39.4 0.0 3.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 EEQ41176.1 - 0.052 13.6 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 BT1 PF03092.16 EEQ41176.1 - 0.23 9.6 0.1 0.31 9.2 0.1 1.2 1 0 0 1 1 1 0 BT1 family OTCace PF00185.24 EEQ41177.1 - 1.9e-47 161.3 0.4 3.2e-47 160.5 0.4 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 EEQ41177.1 - 4.8e-42 143.5 0.2 7.6e-42 142.8 0.2 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Glyco_hydro_4 PF02056.16 EEQ41177.1 - 0.0012 18.4 0.1 0.0022 17.6 0.1 1.5 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase RNA_pol_Rpc34 PF05158.12 EEQ41179.1 - 4.3e-91 305.8 3.0 4.8e-91 305.6 3.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EEQ41179.1 - 0.04 14.1 0.7 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC RPA_C PF08784.11 EEQ41179.1 - 0.11 13.1 0.9 0.17 12.5 0.3 1.7 2 0 0 2 2 2 0 Replication protein A C terminal MarR PF01047.22 EEQ41179.1 - 0.13 12.2 0.8 19 5.3 0.1 2.6 2 0 0 2 2 2 0 MarR family BPL_LplA_LipB PF03099.19 EEQ41180.1 - 1e-06 28.7 0.1 2.2e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TonB_2 PF13103.6 EEQ41180.1 - 0.081 13.2 0.1 7.4 6.9 0.0 3.2 3 0 0 3 3 3 0 TonB C terminal UPF0086 PF01868.16 EEQ41181.1 - 5.1e-20 71.2 0.0 5.1e-20 71.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function UPF0086 Ima1_N PF09779.9 EEQ41181.1 - 0.17 12.7 1.3 0.27 12.1 1.3 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain TCTP PF00838.17 EEQ41181.1 - 0.49 10.7 5.4 1.1 9.6 5.4 1.6 1 1 0 1 1 1 0 Translationally controlled tumour protein DUF1989 PF09347.10 EEQ41183.1 - 1.4e-59 200.4 0.0 1.9e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) NAD_binding_2 PF03446.15 EEQ41184.1 - 1.1e-37 129.6 0.0 1.7e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EEQ41184.1 - 1.2e-14 54.5 0.0 3e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.22 EEQ41184.1 - 0.0048 17.7 0.0 0.0096 16.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DUF2719 PF10891.8 EEQ41184.1 - 0.041 13.8 0.1 0.085 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) F420_oxidored PF03807.17 EEQ41184.1 - 0.047 14.3 0.1 0.29 11.7 0.1 2.3 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EEQ41184.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Arrestin_C PF02752.22 EEQ41185.1 - 2.3e-13 50.8 0.0 7.9e-12 45.8 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EEQ41185.1 - 8e-06 26.0 0.0 0.0012 19.0 0.0 2.8 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain HMG_box_2 PF09011.10 EEQ41186.1 - 0.045 14.3 2.8 0.05 14.2 0.6 2.2 2 0 0 2 2 2 0 HMG-box domain AAR2 PF05282.11 EEQ41187.1 - 1.7e-47 162.5 0.4 3.4e-47 161.6 0.4 1.5 1 1 0 1 1 1 1 AAR2 protein Voltage_CLC PF00654.20 EEQ41188.1 - 1e-66 225.6 27.3 1.6e-66 224.9 27.3 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel WD40 PF00400.32 EEQ41189.1 - 3.8e-19 68.7 5.6 0.0004 21.1 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ41189.1 - 1.5e-09 38.0 0.0 0.00013 22.2 0.0 4.5 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ41189.1 - 4.4e-05 22.3 0.1 0.12 11.0 0.0 2.4 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ41189.1 - 0.0036 16.3 0.1 0.98 8.3 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EEQ41189.1 - 0.11 10.8 0.0 0.85 7.9 0.0 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EEQ41189.1 - 0.14 11.5 0.0 1.7 7.9 0.0 2.4 2 1 0 2 2 2 0 WD40-like domain ALG3 PF05208.13 EEQ41192.1 - 1.6e-127 425.9 17.0 2.1e-127 425.5 17.0 1.1 1 0 0 1 1 1 1 ALG3 protein DUF5033 PF16436.5 EEQ41193.1 - 0.086 12.8 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) PEX11 PF05648.14 EEQ41194.1 - 2.5e-69 233.2 3.6 2.8e-69 233.0 3.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF1449 PF07290.11 EEQ41194.1 - 0.031 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) CCB1 PF12046.8 EEQ41194.1 - 0.085 12.2 0.2 0.13 11.6 0.2 1.4 1 1 0 1 1 1 0 Cofactor assembly of complex C subunit B Keratin_assoc PF09775.9 EEQ41195.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 Spc7 PF08317.11 EEQ41196.1 - 2.5e-66 223.7 21.8 5.1e-66 222.7 21.8 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 EEQ41196.1 - 2.6e-13 49.8 0.1 5.6e-13 48.8 0.1 1.6 1 0 0 1 1 1 1 Spc7_C2 Glutaredoxin2_C PF04399.13 EEQ41196.1 - 0.17 11.8 3.7 19 5.1 0.0 3.5 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain PKcGMP_CC PF16808.5 EEQ41196.1 - 0.44 10.4 6.8 1.7 8.5 6.8 2.1 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF16 PF01519.16 EEQ41196.1 - 0.47 11.0 8.2 0.76 10.3 5.9 2.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Fib_alpha PF08702.10 EEQ41196.1 - 1.5 9.0 12.7 9.4 6.4 12.7 2.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF641 PF04859.12 EEQ41196.1 - 8.6 6.7 12.6 3.2 8.1 7.3 2.6 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) CDC50 PF03381.15 EEQ41197.1 - 2.5e-87 293.0 2.5 3.2e-87 292.6 2.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SdpI PF13630.6 EEQ41197.1 - 0.3 11.3 2.5 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family ADH_zinc_N PF00107.26 EEQ41198.1 - 2.6e-25 88.9 0.3 5.1e-25 87.9 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EEQ41198.1 - 4.1e-24 84.6 0.0 8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EEQ41198.1 - 2.5e-08 35.1 0.0 5.8e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EEQ41199.1 - 6.7e-24 84.3 0.2 1.1e-23 83.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EEQ41199.1 - 1.6e-23 82.6 0.0 2.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EEQ41199.1 - 1.5e-08 35.8 0.0 2.7e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EEQ41199.1 - 0.014 15.2 0.0 0.19 11.4 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) Pkinase PF00069.25 EEQ41200.1 - 3.9e-66 223.1 0.0 7e-66 222.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41200.1 - 1.4e-47 162.2 0.0 3.1e-47 161.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ41200.1 - 9.9e-06 24.6 1.5 4.2e-05 22.5 1.5 1.9 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EEQ41200.1 - 9.6e-05 21.8 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Fe_dep_repress PF01325.19 EEQ41200.1 - 0.047 13.9 0.4 0.12 12.5 0.4 1.7 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Pex2_Pex12 PF04757.14 EEQ41201.1 - 4.4e-35 121.3 8.3 5.5e-35 121.0 8.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 EEQ41201.1 - 1.7e-05 24.7 6.0 3.6e-05 23.6 6.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EEQ41201.1 - 7.1e-05 22.6 5.2 0.00015 21.6 5.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EEQ41201.1 - 0.00032 20.7 3.5 0.00036 20.5 2.4 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EEQ41201.1 - 0.0017 18.5 2.5 0.0017 18.5 2.5 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EEQ41201.1 - 0.01 15.6 4.0 0.01 15.6 4.0 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ41201.1 - 0.032 14.6 8.1 0.07 13.5 8.1 1.6 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 EEQ41201.1 - 0.07 13.0 6.4 0.17 11.8 6.4 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ41201.1 - 0.093 13.0 6.5 0.15 12.3 6.5 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 EEQ41201.1 - 0.098 12.8 4.8 0.21 11.7 4.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger NOA36 PF06524.12 EEQ41201.1 - 0.17 11.2 13.7 0.23 10.8 13.7 1.3 1 0 0 1 1 1 0 NOA36 protein Prok-RING_4 PF14447.6 EEQ41201.1 - 0.42 10.5 6.1 1.1 9.2 6.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 WD40 PF00400.32 EEQ41202.1 - 2.9e-09 37.4 9.0 0.0067 17.3 0.3 6.9 8 0 0 8 8 8 2 WD domain, G-beta repeat Lactonase PF10282.9 EEQ41202.1 - 0.0045 16.3 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller HPS3_N PF14761.6 EEQ41202.1 - 0.078 12.5 0.0 17 4.8 0.0 2.9 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 SART-1 PF03343.13 EEQ41203.1 - 5.7e-41 140.8 65.0 3.8e-29 101.8 52.0 4.1 1 1 2 3 3 3 3 SART-1 family HMA PF00403.26 EEQ41204.1 - 1.1e-48 163.5 2.3 1.3e-14 54.4 0.4 4.5 4 1 0 4 4 4 3 Heavy-metal-associated domain Poly_export PF02563.16 EEQ41204.1 - 0.013 15.7 0.0 33 4.8 0.0 3.5 3 0 0 3 3 3 0 Polysaccharide biosynthesis/export protein DUF3606 PF12244.8 EEQ41204.1 - 0.031 14.2 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) FeS_assembly_P PF01883.19 EEQ41204.1 - 0.064 13.4 3.4 1.8 8.8 0.3 3.5 3 1 1 4 4 4 0 Iron-sulfur cluster assembly protein zinc_ribbon_12 PF11331.8 EEQ41204.1 - 0.24 11.2 2.5 2.8 7.8 0.1 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain SNAD4 PF18750.1 EEQ41204.1 - 0.54 10.4 1.6 8 6.6 0.1 2.7 3 0 0 3 3 3 0 Secreted Novel AID/APOBEC-like Deaminase 4 Fer2_BFD PF04324.15 EEQ41204.1 - 0.61 10.5 4.3 56 4.2 0.0 3.8 3 0 0 3 3 3 0 BFD-like [2Fe-2S] binding domain Hydrolase PF00702.26 EEQ41206.1 - 3.4e-32 112.4 0.0 4.7e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ41206.1 - 2.3e-06 27.5 0.3 7.3e-05 22.6 0.3 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EEQ41206.1 - 0.00012 22.6 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EEQ41206.1 - 0.00057 19.4 2.7 0.00057 19.4 2.7 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HAD_2 PF13419.6 EEQ41206.1 - 0.00097 19.3 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase T2SSF PF00482.23 EEQ41206.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F LicD PF04991.13 EEQ41207.1 - 7.4 6.6 7.2 8.4 6.5 7.2 1.1 1 0 0 1 1 1 0 LicD family Peptidase_S49_N PF08496.10 EEQ41208.1 - 0.02 15.0 2.7 0.02 15.0 2.7 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Coilin_N PF15862.5 EEQ41208.1 - 0.13 12.0 10.3 0.22 11.3 10.3 1.3 1 0 0 1 1 1 0 Coilin N-terminus AP3D1 PF06375.11 EEQ41208.1 - 0.52 10.5 12.2 0.8 9.9 12.2 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Med19 PF10278.9 EEQ41208.1 - 0.57 10.1 12.2 0.87 9.5 12.2 1.2 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Xpo1 PF08389.12 EEQ41209.1 - 6.4e-23 81.5 4.6 6.4e-23 81.5 4.6 3.1 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.19 EEQ41209.1 - 4.6e-08 32.9 0.1 4.4e-07 29.7 0.1 2.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain UME PF08064.13 EEQ41209.1 - 0.15 12.0 0.8 23 4.9 0.0 3.9 4 0 0 4 4 4 0 UME (NUC010) domain HEAT PF02985.22 EEQ41209.1 - 0.98 9.9 5.7 83 3.9 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat Guanylate_kin PF00625.21 EEQ41210.1 - 5.9e-66 221.6 0.0 6.5e-66 221.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EEQ41210.1 - 1.1e-09 38.8 0.0 1.6e-09 38.4 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EEQ41210.1 - 9.7e-05 22.9 0.1 0.00035 21.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ41210.1 - 0.00011 22.4 0.1 0.0037 17.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ41210.1 - 0.00018 21.8 0.0 0.00064 20.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EEQ41210.1 - 0.00019 21.8 0.1 0.00047 20.5 0.0 1.6 2 1 0 2 2 1 1 RNA helicase MMR_HSR1 PF01926.23 EEQ41210.1 - 0.00028 20.9 0.1 0.00079 19.5 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EEQ41210.1 - 0.00052 19.8 0.2 0.0024 17.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EEQ41210.1 - 0.00098 19.4 0.0 0.0022 18.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EEQ41210.1 - 0.0014 19.1 0.0 0.0018 18.8 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 EEQ41210.1 - 0.0015 18.1 0.0 0.005 16.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 EEQ41210.1 - 0.002 17.9 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EEQ41210.1 - 0.0029 17.6 0.0 0.0095 15.9 0.0 1.8 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 EEQ41210.1 - 0.0034 17.4 0.0 0.0089 16.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEQ41210.1 - 0.0038 17.2 0.0 0.0073 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EEQ41210.1 - 0.0049 17.3 0.2 0.013 15.9 0.1 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EEQ41210.1 - 0.0093 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_29 PF13555.6 EEQ41210.1 - 0.011 15.5 1.2 0.021 14.5 0.1 2.0 3 0 0 3 3 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 EEQ41210.1 - 0.011 15.6 0.1 0.036 14.0 0.0 1.8 2 0 0 2 2 2 0 NTPase ATPase_2 PF01637.18 EEQ41210.1 - 0.012 15.5 0.2 0.022 14.7 0.2 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF2075 PF09848.9 EEQ41210.1 - 0.021 14.1 0.0 0.041 13.1 0.0 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EEQ41210.1 - 0.021 14.8 0.0 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EEQ41210.1 - 0.027 13.5 0.0 0.047 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EEQ41210.1 - 0.03 14.6 0.1 0.32 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EEQ41210.1 - 0.084 12.8 0.0 0.21 11.5 0.0 1.7 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Cytidylate_kin PF02224.18 EEQ41210.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase cobW PF02492.19 EEQ41210.1 - 0.087 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 EEQ41210.1 - 0.092 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein KAP_NTPase PF07693.14 EEQ41210.1 - 0.099 11.9 0.1 0.37 10.0 0.0 1.8 1 1 1 2 2 2 0 KAP family P-loop domain AAA_23 PF13476.6 EEQ41210.1 - 0.14 12.7 1.3 0.19 12.2 1.3 1.7 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 EEQ41210.1 - 0.14 12.0 0.4 2.2 8.1 0.1 2.4 1 1 0 2 2 2 0 Deoxynucleoside kinase Pkinase PF00069.25 EEQ41212.1 - 2.1e-47 161.7 0.0 3.3e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41212.1 - 1.3e-27 96.7 0.0 1.7e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ41212.1 - 0.0011 18.4 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EEQ41212.1 - 0.0053 16.1 0.2 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EEQ41213.1 - 1.9e-72 243.8 0.0 2.3e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41213.1 - 7.1e-29 100.9 0.0 1.2e-28 100.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ41213.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ41213.1 - 0.00026 20.0 0.1 0.00099 18.1 0.1 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EEQ41213.1 - 0.00057 19.0 0.1 0.00092 18.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EEQ41213.1 - 0.0031 17.5 0.0 0.0091 15.9 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EEQ41213.1 - 0.015 14.7 0.1 0.038 13.3 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CALCOCO1 PF07888.11 EEQ41214.1 - 0.015 14.2 1.1 0.021 13.7 1.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Laminin_II PF06009.12 EEQ41214.1 - 0.038 14.0 0.9 0.079 13.0 0.9 1.5 1 0 0 1 1 1 0 Laminin Domain II DUF724 PF05266.14 EEQ41214.1 - 0.063 13.1 4.6 0.24 11.2 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Lge1 PF11488.8 EEQ41215.1 - 3.4e-15 56.0 0.0 5.7e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 adh_short PF00106.25 EEQ41216.1 - 2.6e-34 118.4 0.2 4e-34 117.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ41216.1 - 2.1e-20 73.3 0.1 2.9e-20 72.8 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EEQ41216.1 - 0.00031 20.7 0.1 0.0019 18.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 EEQ41216.1 - 0.011 15.9 0.3 0.026 14.8 0.3 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EEQ41216.1 - 0.036 13.2 0.5 0.061 12.4 0.5 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EEQ41216.1 - 0.059 13.4 0.3 0.15 12.1 0.1 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DnaJ_C PF01556.18 EEQ41217.1 - 9.4e-39 132.9 0.0 1.2e-38 132.5 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EEQ41217.1 - 1.9e-23 82.4 0.5 3.1e-23 81.7 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 EEQ41218.1 - 1.7e-41 139.4 22.8 1.1e-08 35.6 0.1 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ41218.1 - 8.1e-14 51.7 4.9 0.0033 17.7 0.2 5.4 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EEQ41218.1 - 8.8e-10 37.8 11.3 0.0051 15.5 0.2 5.0 2 2 0 5 5 5 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ41218.1 - 1.8e-06 27.2 2.5 0.1 11.6 0.0 4.2 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 EEQ41218.1 - 1.4e-05 24.4 0.0 0.0062 15.6 0.0 2.5 1 1 0 2 2 2 2 VID27 C-terminal WD40-like domain Frtz PF11768.8 EEQ41218.1 - 0.00026 19.4 0.0 0.0023 16.4 0.0 2.2 1 1 2 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 EEQ41218.1 - 0.00057 18.7 0.7 1.9 7.1 0.0 3.4 1 1 2 3 3 3 2 Nup133 N terminal like Hira PF07569.11 EEQ41218.1 - 0.00093 19.0 2.9 1.1 9.0 0.1 3.8 2 1 1 3 3 3 2 TUP1-like enhancer of split PALB2_WD40 PF16756.5 EEQ41218.1 - 0.0022 17.0 0.0 0.0022 17.0 0.0 3.0 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 EEQ41218.1 - 0.17 11.1 0.0 2.2 7.5 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain ADH_zinc_N PF00107.26 EEQ41219.1 - 1.8e-24 86.2 0.1 3.5e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EEQ41219.1 - 9.6e-13 49.3 0.1 3.8e-12 47.4 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EEQ41219.1 - 9.4e-09 35.1 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EEQ41219.1 - 0.00086 18.8 0.2 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus adh_short PF00106.25 EEQ41219.1 - 0.048 13.1 0.7 0.1 12.0 0.2 1.8 2 0 0 2 2 2 0 short chain dehydrogenase RFX_DNA_binding PF02257.15 EEQ41220.1 - 3.3e-28 98.1 0.0 6e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 RFX DNA-binding domain Ribosomal_L30 PF00327.20 EEQ41221.1 - 2.3e-08 33.8 0.5 5e-08 32.7 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Dcc1 PF09724.9 EEQ41223.1 - 2.8e-61 207.7 0.0 3.2e-61 207.5 0.0 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Mito_carr PF00153.27 EEQ41224.1 - 3e-32 110.4 0.1 3e-17 62.3 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein Aminotran_5 PF00266.19 EEQ41225.1 - 4.6e-95 318.7 0.0 5.3e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EEQ41225.1 - 2.1e-08 33.8 0.0 2.8e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EEQ41225.1 - 0.00043 19.7 0.1 0.00096 18.6 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 EEQ41225.1 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Iso_dh PF00180.20 EEQ41226.1 - 9.6e-123 409.7 0.0 1.2e-122 409.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_ligase_aden PF01653.18 EEQ41226.1 - 0.21 10.7 0.0 0.43 9.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain DUF3507 PF12015.8 EEQ41227.1 - 4e-45 153.8 0.0 7.4e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) RhoGEF PF00621.20 EEQ41227.1 - 0.0012 19.2 0.7 0.0025 18.1 0.7 1.6 1 0 0 1 1 1 1 RhoGEF domain DUF2015 PF09435.10 EEQ41228.1 - 4.7e-29 100.5 0.1 6.3e-29 100.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) RRM_1 PF00076.22 EEQ41230.1 - 1.1e-47 159.7 0.1 5.4e-20 71.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EEQ41230.1 - 0.00096 19.0 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 Occluded RNA-recognition motif YflT PF11181.8 EEQ41230.1 - 0.015 15.8 1.0 0.14 12.7 0.1 2.8 4 0 0 4 4 4 0 Heat induced stress protein YflT RRM_5 PF13893.6 EEQ41230.1 - 0.18 11.4 0.0 0.67 9.6 0.0 1.8 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.14 EEQ41230.1 - 1.3 7.2 10.0 2.1 6.6 10.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1325 PF07039.11 EEQ41231.1 - 2.8e-36 124.5 0.2 6.1e-36 123.4 0.0 1.6 2 0 0 2 2 2 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EEQ41231.1 - 6.3e-05 22.7 0.0 0.00011 21.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EEQ41231.1 - 0.0053 16.8 0.1 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) Spc7 PF08317.11 EEQ41231.1 - 0.016 14.1 3.8 0.021 13.7 3.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SUIM_assoc PF16619.5 EEQ41231.1 - 0.016 15.3 1.9 0.016 15.3 1.9 1.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 YchF-GTPase_C PF06071.13 EEQ41233.1 - 3.6e-31 107.2 0.0 8.3e-31 106.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EEQ41233.1 - 2.9e-16 59.6 0.1 5.8e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EEQ41233.1 - 5.3e-07 29.6 0.0 1.3e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EEQ41233.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B PLDc_2 PF13091.6 EEQ41234.1 - 3.3e-17 62.6 0.0 7e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EEQ41234.1 - 9.1e-09 35.2 0.0 0.00031 20.8 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif NICE-3 PF07406.11 EEQ41234.1 - 0.051 13.6 0.1 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 NICE-3 protein Ribosomal_L27_C PF18471.1 EEQ41235.1 - 2.4e-43 148.3 1.6 2.9e-43 148.0 1.6 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 EEQ41235.1 - 5.5e-33 112.8 0.0 9.3e-33 112.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Peptidase_M20 PF01546.28 EEQ41236.1 - 7.9e-32 110.6 0.3 1.5e-31 109.7 0.2 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ41236.1 - 3.5e-07 30.1 0.0 6.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ41236.1 - 0.0036 17.0 0.0 0.0079 15.9 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 WD40 PF00400.32 EEQ41237.1 - 6.9e-08 33.0 0.1 0.015 16.1 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat RPN2_C PF18004.1 EEQ41237.1 - 0.003 17.5 8.7 0.0054 16.7 8.7 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 EEQ41237.1 - 0.031 13.7 2.7 0.045 13.2 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 EEQ41237.1 - 0.46 9.2 3.9 0.66 8.7 3.9 1.2 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 EEQ41237.1 - 0.47 8.9 13.7 0.72 8.3 13.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein RR_TM4-6 PF06459.12 EEQ41237.1 - 2.5 7.8 11.9 3.9 7.2 11.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 EEQ41237.1 - 2.7 7.8 11.4 5 6.9 11.4 1.4 1 0 0 1 1 1 0 Coilin N-terminus MCM_bind PF09739.9 EEQ41237.1 - 3.6 5.9 7.4 5.4 5.4 7.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Tim54 PF11711.8 EEQ41237.1 - 4.7 5.9 9.2 7.4 5.2 9.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 EEQ41237.1 - 5.3 7.5 9.8 10 6.6 9.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 EEQ41237.1 - 9.1 5.1 14.7 14 4.5 14.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dynamin_N PF00350.23 EEQ41238.1 - 1.9e-42 145.2 0.0 6.4e-42 143.5 0.0 2.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EEQ41238.1 - 3e-06 27.3 0.0 1e-05 25.6 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 EEQ41238.1 - 0.00038 19.8 4.6 0.025 13.8 1.9 3.1 2 1 0 2 2 2 1 Dynamin central region AAA_16 PF13191.6 EEQ41238.1 - 0.035 14.5 0.2 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TniB PF05621.11 EEQ41238.1 - 0.079 12.4 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 EEQ41238.1 - 0.096 11.9 2.4 4.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.6 EEQ41238.1 - 0.12 12.6 0.2 3.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 EEQ41238.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EEQ41238.1 - 0.22 11.2 0.0 0.22 11.2 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Na_trans_assoc PF06512.13 EEQ41240.1 - 0.63 10.3 5.9 0.87 9.8 5.9 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated NOA36 PF06524.12 EEQ41240.1 - 2.8 7.2 4.2 4.7 6.5 4.2 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_60s PF00428.19 EEQ41242.1 - 1e-25 90.1 15.5 1.2e-25 89.9 15.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Rhomboid PF01694.22 EEQ41243.1 - 1.5e-28 99.7 15.8 2.4e-28 99.0 15.8 1.3 1 0 0 1 1 1 1 Rhomboid family Sec23_trunk PF04811.15 EEQ41245.1 - 7.1e-23 81.4 0.8 6.7e-15 55.3 0.0 2.3 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EEQ41245.1 - 1.3e-18 66.7 0.0 3.2e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EEQ41245.1 - 5.8e-10 39.1 6.2 1.2e-09 38.0 6.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EEQ41245.1 - 2.4e-09 37.8 0.2 6.1e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain DUF393 PF04134.12 EEQ41245.1 - 0.22 12.9 0.5 5.3 8.4 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF393 CASP_C PF08172.12 EEQ41246.1 - 4.6e-70 235.8 7.7 4.6e-70 235.8 7.7 4.2 2 1 0 4 4 4 2 CASP C terminal DUF2935 PF11155.8 EEQ41246.1 - 0.00016 22.0 10.8 0.27 11.6 0.0 4.2 4 1 0 4 4 4 3 Domain of unknown function (DUF2935) TMF_DNA_bd PF12329.8 EEQ41246.1 - 0.0062 16.5 5.0 0.0062 16.5 5.0 8.6 7 3 1 8 8 8 4 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 EEQ41246.1 - 0.0063 16.5 11.6 0.0063 16.5 11.6 6.3 4 1 2 7 7 7 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.15 EEQ41246.1 - 0.0067 16.3 1.9 0.0067 16.3 1.9 6.0 4 2 2 6 6 6 1 Sec34-like family BRE1 PF08647.11 EEQ41246.1 - 0.02 14.9 3.4 0.02 14.9 3.4 7.3 4 2 1 6 6 4 0 BRE1 E3 ubiquitin ligase TMEM192 PF14802.6 EEQ41246.1 - 0.029 13.4 0.3 0.087 11.9 0.3 1.7 1 0 0 1 1 1 0 TMEM192 family Fez1 PF06818.15 EEQ41246.1 - 0.036 14.5 65.1 0.19 12.2 22.8 5.7 1 1 2 4 4 4 0 Fez1 Mto2_bdg PF12808.7 EEQ41246.1 - 0.15 12.3 0.1 0.15 12.3 0.1 6.4 7 0 0 7 7 7 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NPV_P10 PF05531.12 EEQ41246.1 - 2.4 8.7 0.0 2.4 8.7 0.0 5.7 5 2 1 6 6 6 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EEQ41246.1 - 2.8 8.2 20.9 0.8 10.0 0.4 5.3 6 1 0 6 6 6 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 EEQ41246.1 - 3.3 7.9 78.5 2.1 8.5 4.1 6.0 2 1 3 6 6 6 0 Autophagy protein 16 (ATG16) HMMR_N PF15905.5 EEQ41246.1 - 9.5 5.6 70.8 1.2 8.6 14.1 4.6 3 1 1 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Ribosomal_L21e PF01157.18 EEQ41248.1 - 4.2e-40 135.7 5.9 4.4e-40 135.6 4.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 EEQ41248.1 - 0.00036 20.2 0.0 0.00044 19.9 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Diphthami_syn_2 PF01902.17 EEQ41249.1 - 1.9e-37 128.9 0.0 3.8e-37 127.9 0.0 1.5 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EEQ41249.1 - 5.9e-17 61.8 0.0 2.5e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 Endoribonuclease L-PSP PalH PF08733.10 EEQ41250.1 - 1.1e-68 231.7 10.9 1.6e-68 231.2 10.9 1.2 1 0 0 1 1 1 1 PalH/RIM21 NPR3 PF03666.13 EEQ41250.1 - 0.21 10.4 4.3 0.39 9.5 4.3 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Saf_2TM PF18303.1 EEQ41250.1 - 0.58 9.7 2.7 0.45 10.1 0.6 1.8 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain Sec23_trunk PF04811.15 EEQ41251.1 - 8e-34 117.3 0.0 1.6e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EEQ41251.1 - 7.8e-22 77.0 1.5 2.7e-21 75.3 1.4 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EEQ41251.1 - 6.2e-17 62.1 0.0 3.4e-16 59.8 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EEQ41251.1 - 2.7e-09 36.9 4.1 4.9e-09 36.1 4.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger HD_4 PF13328.6 EEQ41251.1 - 0.039 13.7 0.3 0.14 11.9 0.1 1.8 2 0 0 2 2 2 0 HD domain DUF4399 PF14347.6 EEQ41252.1 - 0.012 16.0 1.5 6.3 7.3 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) MgtE PF01769.16 EEQ41252.1 - 2.2 8.7 7.3 5.1 7.5 7.3 1.6 1 0 0 1 1 1 0 Divalent cation transporter UNC45-central PF11701.8 EEQ41253.1 - 1.4e-21 77.1 11.2 2.4e-21 76.3 0.7 3.4 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EEQ41253.1 - 0.044 13.8 2.1 0.15 12.2 0.1 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EEQ41253.1 - 0.097 13.0 1.4 7 7.2 0.1 4.4 5 0 0 5 5 5 0 HEAT repeat TFCD_C PF12612.8 EEQ41253.1 - 0.34 10.7 8.6 2.9 7.7 0.6 3.6 3 1 0 3 3 3 0 Tubulin folding cofactor D C terminal ING PF12998.7 EEQ41254.1 - 5.9e-24 84.6 7.3 8.3e-24 84.1 7.3 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EEQ41254.1 - 9e-07 28.7 8.1 1.5e-06 28.0 8.1 1.4 1 0 0 1 1 1 1 PHD-finger Flagellar_rod PF05149.12 EEQ41254.1 - 0.005 16.3 4.3 0.0067 15.9 4.3 1.1 1 0 0 1 1 1 1 Paraflagellar rod protein PHD_2 PF13831.6 EEQ41254.1 - 0.014 14.9 2.1 0.025 14.1 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H PF13771.6 EEQ41254.1 - 0.018 15.3 0.2 0.05 13.9 0.2 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-C4_Topoisom PF01396.19 EEQ41254.1 - 1.1 9.1 6.7 3.1 7.7 1.0 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Hamartin PF04388.12 EEQ41255.1 - 3.3 6.2 14.8 4.2 5.9 14.8 1.3 1 0 0 1 1 1 0 Hamartin protein CAF1C_H4-bd PF12265.8 EEQ41258.1 - 0.043 14.1 0.1 0.069 13.4 0.1 1.3 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Mgr1 PF08602.10 EEQ41259.1 - 1.8e-18 66.5 1.2 7.4e-09 34.9 0.0 3.1 1 1 2 3 3 3 3 Mgr1-like, i-AAA protease complex subunit Nop14 PF04147.12 EEQ41260.1 - 3.6 5.7 9.3 4.5 5.4 9.3 1.0 1 0 0 1 1 1 0 Nop14-like family bZIP_1 PF00170.21 EEQ41262.1 - 4e-08 33.2 11.4 9.7e-08 32.0 11.4 1.7 1 1 0 1 1 1 1 bZIP transcription factor Shugoshin_N PF07558.11 EEQ41262.1 - 0.0011 18.8 0.9 0.0011 18.8 0.9 1.8 2 1 0 2 2 2 1 Shugoshin N-terminal coiled-coil region GAS PF13851.6 EEQ41262.1 - 0.017 14.4 4.7 0.021 14.2 4.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Phage_GP20 PF06810.11 EEQ41262.1 - 0.018 14.8 1.4 0.025 14.4 1.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Uds1 PF15456.6 EEQ41262.1 - 0.066 13.4 5.2 0.12 12.5 5.2 1.4 1 0 0 1 1 1 0 Up-regulated During Septation CENP-H PF05837.12 EEQ41262.1 - 0.082 13.3 4.1 0.065 13.7 2.8 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) RdRP_1 PF00680.20 EEQ41262.1 - 0.086 11.3 0.4 0.11 11.0 0.4 1.1 1 0 0 1 1 1 0 RNA dependent RNA polymerase PRKG1_interact PF15898.5 EEQ41262.1 - 0.13 13.2 6.0 0.24 12.3 6.0 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain PHA_synth_III_E PF09712.10 EEQ41262.1 - 0.19 10.8 4.5 0.27 10.3 4.5 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) bZIP_Maf PF03131.17 EEQ41262.1 - 0.46 11.0 8.4 0.8 10.3 8.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor Cep57_CLD_2 PF14197.6 EEQ41262.1 - 0.73 10.0 7.4 1.4 9.1 7.4 1.5 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF1003 PF06210.11 EEQ41262.1 - 0.83 9.8 4.2 1.6 8.9 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) DivIC PF04977.15 EEQ41262.1 - 1 9.2 5.1 2.7 7.8 5.1 1.7 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 EEQ41262.1 - 3.1 7.9 17.3 1.5 8.9 1.6 2.2 1 1 1 2 2 2 0 Basic region leucine zipper PBP PF01161.20 EEQ41263.1 - 0.00069 19.9 0.0 0.0014 19.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MIF4G PF02854.19 EEQ41264.1 - 0.00015 21.5 18.6 0.00047 19.8 3.8 4.6 3 1 1 4 4 4 2 MIF4G domain Upf2 PF04050.14 EEQ41264.1 - 0.0013 19.4 12.1 0.0013 19.4 12.1 2.3 2 1 0 2 2 2 1 Up-frameshift suppressor 2 Nop14 PF04147.12 EEQ41264.1 - 0.028 12.7 36.0 0.067 11.4 36.0 1.6 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EEQ41264.1 - 0.045 12.0 22.7 0.082 11.2 22.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Na_trans_assoc PF06512.13 EEQ41264.1 - 0.071 13.4 19.4 0.15 12.3 19.4 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated SDA1 PF05285.12 EEQ41264.1 - 0.3 10.5 31.4 0.62 9.4 31.4 1.4 1 0 0 1 1 1 0 SDA1 DUF2457 PF10446.9 EEQ41264.1 - 0.8 8.8 30.9 1.4 8.0 30.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TLP-20 PF06088.11 EEQ41264.1 - 7.4 6.4 14.2 4.2e+03 -2.5 14.2 2.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SpoIIIAH PF12685.7 EEQ41264.1 - 8.5 6.1 24.8 20 4.9 24.8 1.6 1 0 0 1 1 1 0 SpoIIIAH-like protein SpoIIE PF07228.12 EEQ41265.1 - 1.5e-23 83.7 0.0 2.4e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EEQ41265.1 - 1.3e-10 41.4 0.1 2.4e-05 24.1 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EEQ41265.1 - 4.4e-08 33.0 0.1 8.8e-08 32.0 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF1390 PF07150.11 EEQ41265.1 - 0.18 11.5 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) PNP_phzG_C PF10590.9 EEQ41266.1 - 0.087 12.9 1.3 0.17 12.0 1.3 1.5 1 0 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region ATP-synt_E PF05680.12 EEQ41267.1 - 3.2e-23 81.9 0.4 3.6e-23 81.7 0.4 1.0 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.21 EEQ41268.1 - 1.2e-19 70.2 22.5 6.6e-15 55.0 3.0 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EEQ41268.1 - 2.2e-11 43.3 3.2 6.2e-11 41.9 1.4 2.5 3 0 0 3 3 3 1 Rabenosyn Rab binding domain DUF1856 PF08983.10 EEQ41268.1 - 0.019 15.2 5.2 0.063 13.5 5.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) zf-C2H2_9 PF16293.5 EEQ41268.1 - 0.023 14.5 1.5 0.33 10.8 0.3 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2 PF00096.26 EEQ41268.1 - 0.13 12.8 0.2 0.13 12.8 0.2 4.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type AF-4 PF05110.13 EEQ41268.1 - 0.66 8.0 7.3 0.98 7.4 7.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TackOD1 PF18551.1 EEQ41268.1 - 1.3 8.7 5.9 7.6 6.2 0.7 2.6 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 RAP1 PF07218.11 EEQ41268.1 - 1.5 7.0 4.6 2.1 6.5 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sugar_tr PF00083.24 EEQ41269.1 - 2.1e-111 373.0 20.7 2.4e-111 372.8 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ41269.1 - 5.7e-18 65.0 25.4 5.7e-18 65.0 25.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily CDC45 PF02724.14 EEQ41270.1 - 1.9e-184 614.6 0.1 2.8e-183 610.7 0.1 1.9 1 1 0 1 1 1 1 CDC45-like protein MFMR_assoc PF16596.5 EEQ41270.1 - 0.12 12.9 1.1 0.21 12.0 1.1 1.3 1 0 0 1 1 1 0 Disordered region downstream of MFMR S-antigen PF05756.11 EEQ41270.1 - 0.12 12.7 0.6 0.33 11.4 0.6 1.7 1 0 0 1 1 1 0 S-antigen protein DUF2415 PF10313.9 EEQ41271.1 - 2.9e-16 59.1 0.7 5.5e-16 58.2 0.7 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 EEQ41271.1 - 0.04 14.8 2.4 25 6.0 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Exo_endo_phos PF03372.23 EEQ41273.1 - 4.8e-16 59.0 0.1 6.8e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 3HCDH_RFF PF18321.1 EEQ41273.1 - 0.039 14.4 2.8 0.086 13.3 2.8 1.6 1 0 0 1 1 1 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Spindle_Spc25 PF08234.12 EEQ41274.1 - 3.2e-18 65.7 0.4 3.2e-18 65.7 0.4 2.6 3 0 0 3 3 3 1 Chromosome segregation protein Spc25 Med28 PF11594.8 EEQ41274.1 - 0.0079 16.3 12.4 0.013 15.6 12.4 1.3 1 0 0 1 1 1 1 Mediator complex subunit 28 TPR_MLP1_2 PF07926.12 EEQ41274.1 - 0.0089 16.1 16.0 0.016 15.2 16.0 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein CbiK PF06180.11 EEQ41274.1 - 0.016 14.6 1.6 0.024 14.0 1.0 1.5 1 1 0 1 1 1 0 Cobalt chelatase (CbiK) Spc7 PF08317.11 EEQ41274.1 - 0.021 13.7 17.3 0.029 13.3 17.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 EEQ41274.1 - 0.13 11.3 13.1 0.19 10.8 13.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Baculo_PEP_C PF04513.12 EEQ41274.1 - 0.31 11.1 11.6 2.1 8.4 4.5 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 EEQ41274.1 - 0.31 11.2 17.4 0.62 10.3 17.4 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 EEQ41274.1 - 0.43 10.4 13.4 0.047 13.5 2.8 2.7 1 1 1 2 2 2 0 Septum formation initiator DHR10 PF18595.1 EEQ41274.1 - 0.43 10.6 17.7 1.4 9.0 17.7 1.9 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF2935 PF11155.8 EEQ41274.1 - 0.7 10.2 10.6 1.8 8.9 2.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Tropomyosin_1 PF12718.7 EEQ41274.1 - 0.78 9.9 19.4 1.6 8.9 19.4 1.6 1 1 0 1 1 1 0 Tropomyosin like DUF948 PF06103.11 EEQ41274.1 - 0.81 10.0 6.9 0.49 10.7 3.7 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.6 EEQ41274.1 - 0.93 9.7 17.8 0.17 12.1 7.8 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit V_ATPase_I PF01496.19 EEQ41274.1 - 0.94 7.3 7.8 1 7.2 7.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TFR_dimer PF04253.15 EEQ41274.1 - 1.1 9.4 6.0 3.4 7.8 0.4 2.5 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain Spc24 PF08286.11 EEQ41274.1 - 1.2 9.4 17.0 13 6.1 10.6 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 CdvA PF18822.1 EEQ41274.1 - 1.6 8.6 19.1 0.46 10.3 4.0 2.7 2 1 1 3 3 3 0 CdvA-like coiled-coil domain DUF3450 PF11932.8 EEQ41274.1 - 2 7.7 15.6 3.1 7.1 15.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DUF4140 PF13600.6 EEQ41274.1 - 2.2 8.8 10.4 3.2 8.3 1.7 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) NPV_P10 PF05531.12 EEQ41274.1 - 3.9 8.0 10.7 8.4 6.9 7.1 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Med9 PF07544.13 EEQ41274.1 - 5.9 7.1 14.9 3.1 8.0 7.3 2.6 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 CHD5 PF04420.14 EEQ41274.1 - 7.8 6.3 9.3 0.97 9.3 4.0 2.1 1 1 1 2 2 2 0 CHD5-like protein ApoO PF09769.9 EEQ41274.1 - 9.1 6.2 6.1 26 4.8 0.2 2.5 1 1 1 2 2 2 0 Apolipoprotein O GABP-alpha PF11620.8 EEQ41276.1 - 0.034 14.3 0.2 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF2470 PF10615.9 EEQ41277.1 - 2.2e-13 50.6 0.0 2.8e-12 47.1 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 EEQ41277.1 - 0.01 16.2 0.1 0.022 15.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) TFIID_30kDa PF03540.13 EEQ41279.1 - 4.9e-26 90.4 0.1 8.6e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EEQ41279.1 - 0.017 15.6 1.1 0.017 15.6 1.1 2.1 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 TAF4 PF05236.14 EEQ41279.1 - 0.1 12.3 2.8 0.87 9.3 3.1 2.0 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Zn_ribbon_17 PF17120.5 EEQ41280.1 - 2.4e-13 49.5 17.7 1.1e-12 47.4 17.7 2.0 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EEQ41280.1 - 0.00089 20.0 22.5 0.0012 19.7 0.1 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat zf-RING_2 PF13639.6 EEQ41280.1 - 0.059 13.7 6.3 0.13 12.7 6.3 1.6 1 0 0 1 1 1 0 Ring finger domain adh_short PF00106.25 EEQ41281.1 - 3.3e-07 30.0 0.0 2.3e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EEQ41281.1 - 0.00056 19.5 0.0 0.23 11.0 0.0 3.0 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.25 EEQ41282.1 - 6.2e-66 222.5 0.0 7.9e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41282.1 - 3.4e-34 118.3 0.0 6.7e-34 117.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ41282.1 - 3.7e-07 29.4 0.5 6.1e-07 28.7 0.3 1.4 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 EEQ41282.1 - 0.009 15.6 0.2 0.016 14.8 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EEQ41282.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EEQ41282.1 - 0.053 13.4 0.1 0.26 11.2 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EEQ41282.1 - 0.12 12.0 0.1 0.48 10.0 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 EEQ41283.1 - 8.8e-25 87.4 4.7 9.9e-25 87.2 4.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily HECT PF00632.25 EEQ41284.1 - 4.2e-77 259.6 0.0 7.4e-77 258.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1400 PF07176.11 EEQ41284.1 - 0.12 12.7 0.4 5.4 7.3 0.0 2.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1400) IL5 PF02025.15 EEQ41284.1 - 0.13 12.6 0.3 0.6 10.4 0.1 2.3 2 0 0 2 2 2 0 Interleukin 5 Ssl1 PF04056.14 EEQ41284.1 - 0.16 11.7 2.0 3 7.6 0.1 3.2 3 0 0 3 3 3 0 Ssl1-like F-actin_cap_A PF01267.17 EEQ41285.1 - 2e-66 224.1 1.2 2.3e-66 224.0 1.2 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Fijivirus_P9-2 PF06837.11 EEQ41286.1 - 0.036 13.5 0.0 0.039 13.4 0.0 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein PilJ PF13675.6 EEQ41286.1 - 0.059 13.4 0.1 0.076 13.0 0.1 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term MAP65_ASE1 PF03999.12 EEQ41286.1 - 0.1 11.3 0.1 0.12 11.1 0.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF948 PF06103.11 EEQ41286.1 - 0.62 10.4 3.1 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) VHS PF00790.19 EEQ41287.1 - 3.6e-30 104.7 0.5 6.3e-30 103.9 0.5 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EEQ41287.1 - 8.1e-15 54.2 0.0 1.8e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EEQ41287.1 - 7.5e-12 44.8 0.0 1.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EEQ41287.1 - 1.6e-11 43.9 0.1 3.4e-11 42.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EEQ41287.1 - 2.9e-06 27.5 1.5 6e-06 26.5 0.6 2.1 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EEQ41287.1 - 0.068 13.1 0.8 0.18 11.8 0.8 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif TRAM_LAG1_CLN8 PF03798.16 EEQ41288.1 - 1.5e-38 132.5 25.5 1.5e-38 132.5 25.5 2.6 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EEQ41288.1 - 1.4e-19 69.5 0.1 1.4e-19 69.5 0.1 2.8 3 0 0 3 3 3 1 TRAM1-like protein Ribosomal_S2 PF00318.20 EEQ41289.1 - 6.9e-66 221.5 0.1 6.9e-66 221.5 0.1 2.7 2 2 0 2 2 2 1 Ribosomal protein S2 7tm_7 PF08395.12 EEQ41289.1 - 0.063 12.5 0.4 0.086 12.0 0.4 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Hep_59 PF07052.11 EEQ41289.1 - 0.27 12.0 4.6 3.2 8.5 0.1 3.1 2 1 1 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 CS PF04969.16 EEQ41291.1 - 0.0024 18.8 0.0 0.005 17.8 0.0 1.5 2 0 0 2 2 2 1 CS domain Syja_N PF02383.18 EEQ41293.1 - 3.7e-80 269.6 1.3 3.7e-80 269.6 1.3 2.2 2 0 0 2 2 2 1 SacI homology domain SNF5 PF04855.12 EEQ41294.1 - 1.7e-52 178.6 3.4 7.3e-31 107.8 0.9 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 MafB19-deam PF14437.6 EEQ41295.1 - 1.2e-08 34.8 0.1 2.4e-08 33.8 0.1 1.6 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EEQ41295.1 - 6.6e-08 32.4 0.0 9.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 EEQ41295.1 - 0.018 15.1 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase DUF5099 PF17025.5 EEQ41295.1 - 0.065 13.6 0.0 0.23 11.9 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5099) TrmB PF01978.19 EEQ41295.1 - 0.098 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Imm3 PF14425.6 EEQ41295.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 Telomerase_RBD PF12009.8 EEQ41296.1 - 9.6e-28 97.0 4.0 6e-27 94.4 2.7 2.7 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EEQ41296.1 - 3.1e-12 46.5 3.0 2e-09 37.3 0.0 3.1 3 0 0 3 3 3 2 Reverse transcriptase (RNA-dependent DNA polymerase) RAI1 PF08652.11 EEQ41296.1 - 2.4 8.4 4.5 0.76 10.0 0.5 2.2 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease AIP3 PF03915.13 EEQ41297.1 - 2.2e-129 432.2 20.1 2.2e-129 432.2 20.1 1.9 2 0 0 2 2 2 1 Actin interacting protein 3 Baculo_PEP_C PF04513.12 EEQ41297.1 - 2 8.5 13.1 4.2 7.4 0.1 4.8 3 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 EEQ41297.1 - 7.8 6.4 5.8 3.3 7.6 0.5 3.3 4 0 0 4 4 4 0 DASH complex subunit Dam1 Importin_rep_6 PF18829.1 EEQ41298.1 - 1.4e-35 121.7 1.2 1.4e-35 121.7 1.2 3.7 4 0 0 4 4 4 1 Importin repeat 6 Importin_rep_4 PF18808.1 EEQ41298.1 - 3.2e-30 104.3 7.4 2.2e-29 101.6 0.7 4.5 4 0 0 4 4 4 1 Importin repeat Importin_rep_5 PF18816.1 EEQ41298.1 - 5.3e-19 68.3 0.1 2.1e-18 66.4 0.1 2.1 1 0 0 1 1 1 1 Importin repeat HEAT_2 PF13646.6 EEQ41298.1 - 3e-16 59.6 10.1 1.8e-05 25.1 0.1 8.7 5 3 3 8 8 8 5 HEAT repeats HEAT_EZ PF13513.6 EEQ41298.1 - 1.1e-14 54.5 23.0 1.4e-08 35.0 0.1 9.2 9 2 2 11 11 10 3 HEAT-like repeat HEAT PF02985.22 EEQ41298.1 - 1.8e-13 49.5 24.5 0.031 14.5 0.0 11.8 13 0 0 13 13 12 3 HEAT repeat MMS19_C PF12460.8 EEQ41298.1 - 3.3e-12 46.2 15.8 0.00025 20.3 3.0 5.6 3 3 2 5 5 5 4 RNAPII transcription regulator C-terminal RIX1 PF08167.12 EEQ41298.1 - 6e-07 29.4 6.3 0.036 13.8 0.1 5.8 6 0 0 6 6 6 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EEQ41298.1 - 6.2e-07 29.2 3.1 0.077 12.6 0.0 5.7 6 1 1 7 7 7 2 CLASP N terminal DUF3385 PF11865.8 EEQ41298.1 - 1.1e-06 28.6 1.6 20 5.0 0.0 7.7 7 2 1 9 9 8 0 Domain of unknown function (DUF3385) ParcG PF10274.9 EEQ41298.1 - 1.3e-06 28.7 2.7 0.047 13.8 0.0 5.2 4 1 1 5 5 5 1 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 EEQ41298.1 - 1.9e-06 28.4 0.2 1.6 9.3 0.0 5.7 5 2 1 6 6 4 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EEQ41298.1 - 0.0025 18.0 0.9 4.7 7.4 0.4 5.4 4 1 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EEQ41298.1 - 0.0057 16.6 15.0 1.7 8.8 0.0 7.1 9 0 0 9 9 7 1 Armadillo/beta-catenin-like repeat RNA_pol_Rpb2_2 PF04561.14 EEQ41298.1 - 0.053 13.1 0.7 0.17 11.5 0.7 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 2 Xpo1 PF08389.12 EEQ41298.1 - 0.08 13.0 8.0 8.4 6.4 0.0 6.0 5 3 0 5 5 5 0 Exportin 1-like protein Cnd3 PF12719.7 EEQ41298.1 - 0.083 12.1 0.8 5.2 6.2 0.0 3.8 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain DNA_alkylation PF08713.11 EEQ41298.1 - 0.09 12.5 0.0 0.43 10.3 0.0 2.2 1 0 0 1 1 1 0 DNA alkylation repair enzyme UNC45-central PF11701.8 EEQ41298.1 - 0.22 11.5 7.5 14 5.6 0.0 5.1 4 2 2 6 6 6 0 Myosin-binding striated muscle assembly central DUF4303 PF14136.6 EEQ41298.1 - 1.4 8.6 5.6 0.28 10.9 0.2 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF4303) zf-piccolo PF05715.13 EEQ41298.1 - 1.8 8.8 4.7 0.67 10.1 0.1 2.6 3 0 0 3 3 3 0 Piccolo Zn-finger MMR_HSR1_Xtn PF16897.5 EEQ41299.1 - 6.1e-38 129.1 1.1 1.6e-37 127.7 0.1 2.2 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EEQ41299.1 - 1.7e-22 79.2 0.1 3.6e-22 78.2 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EEQ41299.1 - 1.4e-21 76.7 0.4 5.2e-21 74.9 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ41299.1 - 9.6e-10 38.2 0.0 2.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EEQ41299.1 - 0.01 14.8 0.7 0.022 13.7 0.2 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EEQ41299.1 - 0.011 15.8 2.7 2.1 8.4 0.0 2.6 2 1 1 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 EEQ41299.1 - 0.3 11.0 4.0 3.3 7.6 0.5 3.3 2 2 1 3 3 3 0 RsgA GTPase GTP_EFTU PF00009.27 EEQ41300.1 - 2e-32 112.3 0.0 2e-32 112.3 0.0 2.8 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EEQ41300.1 - 2.5e-21 75.8 0.0 9.6e-21 73.9 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EEQ41300.1 - 1.4e-09 38.1 8.0 4.8e-08 33.3 0.0 3.8 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EEQ41300.1 - 1.2e-07 31.9 0.2 4.5e-06 26.7 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EEQ41300.1 - 5.8e-06 26.1 0.1 2.3e-05 24.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 EEQ41300.1 - 0.00018 21.7 0.0 0.00062 20.0 0.0 1.9 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EEQ41300.1 - 0.0035 17.2 0.0 0.0035 17.2 0.0 2.7 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EEQ41300.1 - 0.0081 15.7 0.0 0.068 12.7 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EEQ41300.1 - 0.051 13.5 0.4 0.77 9.6 0.1 3.0 2 1 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EEQ41300.1 - 0.091 13.0 0.4 0.87 9.9 0.4 2.7 1 1 0 1 1 1 0 AAA domain Hydrolase_6 PF13344.6 EEQ41301.1 - 3.7e-29 100.8 0.0 6.5e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ41301.1 - 7.2e-16 58.0 0.0 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EEQ41301.1 - 6.2e-07 29.9 0.0 1.9e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ41301.1 - 0.031 14.3 2.8 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EEQ41301.1 - 0.13 11.9 0.1 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Hpt PF01627.23 EEQ41302.1 - 1.2e-10 41.5 0.0 1.8e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Hpt domain DUF4895 PF16236.5 EEQ41302.1 - 0.05 13.4 0.3 0.071 12.9 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4895) PG_binding_2 PF08823.11 EEQ41302.1 - 0.066 13.5 0.2 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Glyco_transf_22 PF03901.17 EEQ41303.1 - 2.9e-81 273.9 28.3 3.5e-81 273.6 28.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Adenylsucc_synt PF00709.21 EEQ41304.1 - 2.1e-147 491.4 0.0 2.4e-147 491.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Iso_dh PF00180.20 EEQ41306.1 - 4.3e-57 193.8 0.0 4.9e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Complex1_LYR_2 PF13233.6 EEQ41308.1 - 6e-19 68.6 3.5 1.4e-18 67.4 3.5 1.6 1 1 0 1 1 1 1 Complex1_LYR-like YedD PF13987.6 EEQ41308.1 - 0.11 12.4 1.5 0.33 10.8 0.1 2.0 2 0 0 2 2 2 0 YedD-like protein Com_YlbF PF06133.11 EEQ41308.1 - 0.42 11.2 4.8 1.3 9.7 4.8 1.7 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Acetyltransf_13 PF13880.6 EEQ41309.1 - 0.009 16.0 0.0 4.5 7.3 0.0 3.5 3 1 1 4 4 4 2 ESCO1/2 acetyl-transferase DSPc PF00782.20 EEQ41309.1 - 0.027 14.3 1.4 0.33 10.7 0.3 2.6 1 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain FUN14 PF04930.15 EEQ41311.1 - 8.6e-09 35.7 0.8 8.6e-09 35.7 0.8 1.7 2 1 0 2 2 2 1 FUN14 family RNA_pol_Rpb1_5 PF04998.17 EEQ41312.1 - 2.9e-96 322.0 0.2 5.7e-96 321.0 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EEQ41312.1 - 3.6e-70 235.5 0.3 8e-70 234.4 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EEQ41312.1 - 1.6e-39 135.4 0.0 3.8e-38 130.9 0.0 3.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EEQ41312.1 - 8.1e-23 80.4 2.9 8.8e-23 80.3 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.12 EEQ41312.1 - 0.069 12.5 0.2 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 1 DUF4368 PF14287.6 EEQ41312.1 - 0.099 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) BUD22 PF09073.10 EEQ41312.1 - 4.5 6.5 23.5 7.4 5.8 23.5 1.2 1 0 0 1 1 1 0 BUD22 Glycos_transf_4 PF00953.21 EEQ41313.1 - 3.5e-33 114.8 9.5 3.5e-33 114.8 9.5 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 WD40 PF00400.32 EEQ41314.1 - 4.7e-23 81.0 7.7 3.8e-06 27.5 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ41314.1 - 3.3e-11 43.3 0.3 0.0091 16.3 0.1 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ41314.1 - 9.3e-06 24.8 0.3 0.039 12.9 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TIMP PF00965.17 EEQ41314.1 - 0.082 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Tissue inhibitor of metalloproteinase YmzC PF14157.6 EEQ41314.1 - 0.11 12.6 0.0 10 6.3 0.0 2.9 3 0 0 3 3 3 0 YmzC-like protein ANAPC4_WD40 PF12894.7 EEQ41315.1 - 0.06 13.7 0.0 12 6.3 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 EEQ41317.1 - 2e-51 174.9 1.8 7.5e-51 173.0 1.5 1.8 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ41317.1 - 2.6e-08 33.1 0.0 3.9e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.8 EEQ41317.1 - 0.015 14.4 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; NAD-GH PF10712.9 EEQ41318.1 - 1.3e-16 60.2 15.8 1.3e-16 60.2 15.8 1.9 2 0 0 2 2 2 1 NAD-specific glutamate dehydrogenase MLD PF11647.8 EEQ41318.1 - 0.26 11.6 1.0 32 4.9 0.1 3.0 3 0 0 3 3 3 0 Membrane Localization Domain RabGAP-TBC PF00566.18 EEQ41320.1 - 1.4e-48 165.4 0.0 2.2e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain THF_DHG_CYH PF00763.23 EEQ41323.1 - 5.8e-27 94.3 0.0 1.7e-26 92.8 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EEQ41323.1 - 1.2e-16 60.4 0.1 6.9e-14 51.5 0.1 2.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TgMIC1 PF11476.8 EEQ41323.1 - 0.07 12.9 0.1 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Myb_DNA-binding PF00249.31 EEQ41324.1 - 4e-35 119.7 7.1 1.5e-12 47.5 0.4 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EEQ41324.1 - 2.7e-33 114.0 0.1 1.3e-12 47.7 0.0 3.5 2 1 1 3 3 3 3 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 EEQ41324.1 - 0.0072 16.6 1.2 5.6 7.3 0.0 3.2 2 1 1 3 3 3 2 Alcohol dehydrogenase transcription factor Myb/SANT-like AAR2 PF05282.11 EEQ41324.1 - 0.13 11.6 2.5 0.24 10.8 2.5 1.4 1 0 0 1 1 1 0 AAR2 protein HTH_Tnp_1 PF01527.20 EEQ41324.1 - 0.14 12.5 3.7 0.89 9.9 0.7 3.1 3 0 0 3 3 3 0 Transposase Myb_DNA-bind_7 PF15963.5 EEQ41324.1 - 0.33 10.9 5.1 0.62 10.0 0.0 3.2 4 0 0 4 4 4 0 Myb DNA-binding like UCH PF00443.29 EEQ41327.1 - 1.5e-50 172.1 0.1 1.5e-50 172.1 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ41327.1 - 4e-18 66.1 0.1 6.9e-18 65.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rubredoxin_2 PF18073.1 EEQ41327.1 - 0.35 10.6 3.9 10 6.0 0.2 2.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain Kin17_mid PF10357.9 EEQ41328.1 - 1.1e-35 122.3 8.7 9.7e-35 119.2 8.6 2.1 1 1 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 EEQ41328.1 - 3e-06 27.4 2.1 5.6e-06 26.5 2.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EEQ41328.1 - 8.8e-05 22.8 2.6 0.00017 21.9 2.6 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type Spore_YhcN_YlaJ PF09580.10 EEQ41328.1 - 0.0032 17.5 0.4 0.22 11.6 0.0 2.2 2 0 0 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) DUF640 PF04852.12 EEQ41328.1 - 0.018 15.2 0.7 0.075 13.2 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF640) zf-C2H2_2 PF12756.7 EEQ41328.1 - 0.037 14.3 1.8 0.087 13.2 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 EEQ41328.1 - 2.4 8.4 8.1 0.99 9.6 0.1 2.8 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) Presenilin PF01080.17 EEQ41328.1 - 3.3 6.4 6.0 4.3 6.0 6.0 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_M48 PF01435.18 EEQ41330.1 - 5.1e-26 91.7 0.0 1e-25 90.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 Zincin_1 PF06262.11 EEQ41330.1 - 0.075 13.1 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase MbeD_MobD PF04899.12 EEQ41332.1 - 0.1 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 MbeD/MobD like SKG6 PF08693.10 EEQ41333.1 - 0.027 13.9 0.7 0.048 13.1 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 EEQ41333.1 - 0.095 13.6 0.0 0.22 12.4 0.0 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Extensin-like_C PF06904.12 EEQ41335.1 - 0.08 13.0 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Extensin-like protein C-terminus Coa1 PF08695.10 EEQ41336.1 - 5.9e-39 132.4 0.0 7.4e-39 132.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Calreticulin PF00262.18 EEQ41337.1 - 9.2e-134 445.9 2.2 1.2e-133 445.5 2.2 1.2 1 0 0 1 1 1 1 Calreticulin family LapA_dom PF06305.11 EEQ41337.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain OAD_gamma PF04277.13 EEQ41337.1 - 2 9.0 7.1 0.54 10.9 1.6 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Exo_endo_phos PF03372.23 EEQ41338.1 - 7.7e-14 51.8 0.8 3e-13 49.8 0.8 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EEQ41338.1 - 0.00045 20.1 0.0 0.048 13.5 0.0 2.5 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase Sugar_tr PF00083.24 EEQ41339.1 - 8.5e-43 146.8 22.0 5.3e-42 144.2 22.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EEQ41339.1 - 2.9e-31 108.7 26.6 2.9e-31 108.7 26.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TRAPPC10 PF12584.8 EEQ41341.1 - 4.3e-17 62.3 0.0 1e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Gryzun-like PF12742.7 EEQ41341.1 - 4.7e-06 26.5 0.3 3.9e-05 23.6 0.1 2.5 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Foie-gras_1 PF11817.8 EEQ41341.1 - 0.0054 16.4 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 Foie gras liver health family 1 TRAPPC9-Trs120 PF08626.11 EEQ41341.1 - 0.0096 13.3 1.1 0.014 12.8 1.1 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF410 PF04190.13 EEQ41341.1 - 0.024 14.4 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) CUE PF02845.16 EEQ41342.1 - 2.3e-09 36.8 0.1 4.6e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 CUE domain Pribosyl_synth PF14572.6 EEQ41343.1 - 7.2e-39 133.7 0.3 1.1e-38 133.1 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EEQ41343.1 - 9.5e-33 112.6 0.0 2.6e-32 111.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EEQ41343.1 - 2.4e-14 53.1 0.2 6.1e-14 51.8 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Adap_comp_sub PF00928.21 EEQ41344.1 - 1.1e-68 231.5 0.0 1.4e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEQ41344.1 - 3.1e-12 46.6 0.0 4.9e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EEQ41344.1 - 0.062 12.7 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain ELFV_dehydrog PF00208.21 EEQ41345.1 - 4.4e-65 219.8 0.0 6.6e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EEQ41345.1 - 6.4e-20 70.4 0.2 6.7e-15 53.8 0.1 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EEQ41345.1 - 0.005 16.7 0.0 0.04 13.8 0.0 2.5 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Ubiquitin_3 PF14836.6 EEQ41345.1 - 0.032 14.2 0.0 0.1 12.6 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin-like domain Lactonase PF10282.9 EEQ41346.1 - 0.09 12.0 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller WH2 PF02205.20 EEQ41348.1 - 3.1e-13 49.1 0.1 1.5e-10 40.6 0.1 3.3 3 0 0 3 3 3 2 WH2 motif AAA_18 PF13238.6 EEQ41349.1 - 2.1e-06 28.3 0.0 3.6e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 EEQ41349.1 - 1.6e-05 24.8 0.1 4.1e-05 23.4 0.1 1.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EEQ41349.1 - 0.00051 20.2 0.0 0.0015 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EEQ41349.1 - 0.00086 19.1 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EEQ41349.1 - 0.023 15.2 0.0 0.043 14.3 0.0 1.7 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 EEQ41349.1 - 0.024 14.5 0.0 0.041 13.7 0.0 1.6 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 EEQ41349.1 - 0.045 14.1 0.0 0.066 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin PF02224.18 EEQ41349.1 - 0.06 13.1 0.3 0.11 12.2 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 EEQ41349.1 - 0.063 13.5 0.1 0.18 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain tRNA_lig_kinase PF08303.11 EEQ41349.1 - 0.099 12.7 0.0 0.19 11.8 0.0 1.5 2 0 0 2 2 2 0 tRNA ligase kinase domain AAA_22 PF13401.6 EEQ41349.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EEQ41351.1 - 2.1e-36 125.6 33.8 8.7e-31 107.1 22.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily CC PF04942.14 EEQ41352.1 - 0.04 14.1 0.9 4.6 7.5 0.1 2.7 2 0 0 2 2 2 0 CC domain Snf7 PF03357.21 EEQ41353.1 - 2.1e-47 160.9 13.9 2.5e-47 160.7 13.9 1.0 1 0 0 1 1 1 1 Snf7 CAMSAP_CC1 PF17095.5 EEQ41353.1 - 0.045 13.6 1.6 0.096 12.6 1.6 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Exonuc_VII_L PF02601.15 EEQ41353.1 - 0.17 11.5 4.5 0.2 11.2 4.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2120 PF09893.9 EEQ41353.1 - 0.37 10.9 3.3 0.3 11.2 1.3 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) FlaC_arch PF05377.11 EEQ41353.1 - 0.67 10.4 0.0 0.67 10.4 0.0 3.7 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) DUF4559 PF15112.6 EEQ41353.1 - 0.72 9.5 9.3 0.94 9.1 9.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Prefoldin PF02996.17 EEQ41353.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.4 2 1 0 3 3 3 0 Prefoldin subunit Atg14 PF10186.9 EEQ41353.1 - 2.1 7.3 10.2 6 5.8 10.4 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EEQ41353.1 - 5 5.6 11.9 0.95 8.0 4.7 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A SlyX PF04102.12 EEQ41353.1 - 6.3 7.5 12.3 28 5.4 0.0 3.8 1 1 2 4 4 4 0 SlyX EMP24_GP25L PF01105.24 EEQ41353.1 - 7.2 6.5 7.5 10 6.0 0.0 2.8 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD H2TH PF06831.14 EEQ41354.1 - 1e-14 54.3 0.0 2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 EEQ41354.1 - 3.3e-11 43.8 0.0 6.3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain Malic_M PF03949.15 EEQ41355.1 - 1.1e-83 280.5 0.0 1.4e-83 280.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EEQ41355.1 - 1e-61 207.9 0.0 1.7e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Say1_Mug180 PF10340.9 EEQ41356.1 - 1.3e-28 100.0 0.1 2.2e-28 99.2 0.1 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EEQ41356.1 - 6.2e-10 39.3 0.0 8.9e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold SF3A3 PF16837.5 EEQ41356.1 - 0.018 15.5 0.4 1.3 9.6 0.0 3.0 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 UMPH-1 PF05822.12 EEQ41356.1 - 0.073 12.6 0.0 0.85 9.1 0.0 2.1 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase_4 PF12146.8 EEQ41356.1 - 0.089 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Say1_Mug180 PF10340.9 EEQ41357.1 - 3.4e-26 92.0 0.2 5.3e-26 91.4 0.2 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 EEQ41357.1 - 3e-12 46.8 0.0 4.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EEQ41357.1 - 0.094 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 NADH_u_ox_C PF12853.7 EEQ41357.1 - 0.37 10.8 1.7 4 7.5 0.1 2.4 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit RVT_2 PF07727.14 EEQ41358.1 - 3.4e-26 92.4 0.0 9.1e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HIT PF01230.23 EEQ41358.1 - 0.049 14.4 0.2 1.3 9.8 0.0 3.1 4 0 0 4 4 4 0 HIT domain ADK PF00406.22 EEQ41359.1 - 3.7e-61 205.7 0.0 5.2e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EEQ41359.1 - 4.7e-23 82.1 0.3 1.3e-22 80.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 EEQ41359.1 - 5.1e-17 61.6 0.1 1.3e-16 60.3 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EEQ41359.1 - 5.3e-06 27.0 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EEQ41359.1 - 3.7e-05 23.9 0.0 8.5e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain CART PF06373.11 EEQ41359.1 - 0.0014 18.8 0.1 0.0063 16.7 0.1 2.1 2 0 0 2 2 2 1 Cocaine and amphetamine regulated transcript protein (CART) Cytidylate_kin PF02224.18 EEQ41359.1 - 0.043 13.6 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 EEQ41359.1 - 0.056 13.2 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain CFIA_Pcf11 PF11526.8 EEQ41360.1 - 8.2e-12 45.4 13.8 3.1e-10 40.4 5.9 3.3 2 1 0 2 2 2 1 Subunit of cleavage factor IA Pcf11 Prok-RING_1 PF14446.6 EEQ41360.1 - 0.79 9.7 2.9 6 6.9 0.6 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf_UBZ PF18439.1 EEQ41360.1 - 1.7 8.3 4.4 14 5.4 4.4 2.3 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Mito_carr PF00153.27 EEQ41361.1 - 1.1e-30 105.4 1.4 8e-15 54.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF410 PF04190.13 EEQ41362.1 - 0.098 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF410) DUF2189 PF09955.9 EEQ41364.1 - 0.081 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2189) DUF2235 PF09994.9 EEQ41365.1 - 2.6e-74 250.2 0.0 3.6e-74 249.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) UCR_TM PF02921.14 EEQ41366.1 - 4.3e-11 43.1 0.4 9.4e-11 42.0 0.4 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EEQ41366.1 - 5.9e-11 42.2 0.0 9.8e-11 41.5 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain HECT PF00632.25 EEQ41368.1 - 1.5e-77 261.1 0.0 2.1e-77 260.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MMS1_N PF10433.9 EEQ41369.1 - 2.8e-10 39.4 0.0 9.3e-10 37.7 0.0 1.8 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.6 EEQ41369.1 - 0.47 11.0 6.5 4.3 8.0 0.0 5.3 6 0 0 6 6 6 0 PQQ-like domain Nucleopor_Nup85 PF07575.13 EEQ41370.1 - 1.4e-64 218.7 0.0 1.7e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Nup85 Nucleoporin Ribosomal_L7Ae PF01248.26 EEQ41371.1 - 9.1e-27 92.6 0.0 1.1e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EEQ41371.1 - 0.00047 20.2 0.1 0.00048 20.2 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EEQ41371.1 - 0.00052 19.9 0.0 0.00068 19.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain Pico_P2B PF01552.17 EEQ41371.1 - 0.025 14.7 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 Picornavirus 2B protein Urb2 PF10441.9 EEQ41372.1 - 4.2e-50 170.5 1.9 1.2e-49 169.1 1.9 1.8 1 0 0 1 1 1 1 Urb2/Npa2 family Roughex PF06020.11 EEQ41372.1 - 0.027 13.6 0.1 0.027 13.6 0.1 2.6 4 0 0 4 4 4 0 Drosophila roughex protein MecA PF05389.12 EEQ41372.1 - 0.31 10.7 11.9 13 5.3 1.3 4.2 4 0 0 4 4 4 0 Negative regulator of genetic competence (MecA) RICTOR_N PF14664.6 EEQ41372.1 - 0.53 9.2 0.0 0.53 9.2 0.0 3.6 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term DUF2722 PF10846.8 EEQ41372.1 - 0.67 8.8 25.0 0.057 12.4 0.7 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2722) Voltage_CLC PF00654.20 EEQ41373.1 - 1.5e-82 277.7 23.8 1.5e-82 277.7 23.8 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EEQ41373.1 - 2.8e-11 43.7 0.4 1.5e-06 28.6 0.5 2.5 2 0 0 2 2 2 2 CBS domain AATase PF07247.12 EEQ41374.1 - 1.2e-28 100.0 0.0 8.5e-23 80.7 0.0 2.3 2 1 0 2 2 2 2 Alcohol acetyltransferase Carn_acyltransf PF00755.20 EEQ41374.1 - 0.047 12.3 0.0 0.068 11.8 0.0 1.2 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase Syntaxin_2 PF14523.6 EEQ41375.1 - 4.5e-20 71.9 1.3 4.5e-20 71.9 1.3 2.2 2 0 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EEQ41375.1 - 1e-15 57.5 0.2 2.1e-15 56.5 0.2 1.6 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 EEQ41375.1 - 0.00039 20.1 0.2 0.00095 18.9 0.2 1.7 1 0 0 1 1 1 1 Synaptobrevin PRP21_like_P PF12230.8 EEQ41375.1 - 0.0062 16.4 0.3 0.01 15.7 0.3 1.4 1 0 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Prominin PF05478.11 EEQ41375.1 - 0.024 12.6 5.6 0.05 11.6 5.5 1.5 1 1 0 1 1 1 0 Prominin SOAR PF16533.5 EEQ41375.1 - 0.048 13.6 0.6 0.048 13.6 0.6 2.4 2 1 0 2 2 2 0 STIM1 Orai1-activating region Consortin_C PF15281.6 EEQ41375.1 - 0.054 13.5 0.3 0.22 11.6 0.1 2.0 2 0 0 2 2 2 0 Consortin C-terminus Use1 PF09753.9 EEQ41375.1 - 0.065 13.0 5.7 0.22 11.2 5.7 1.9 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF1664 PF07889.12 EEQ41375.1 - 0.089 12.8 6.2 1.5 8.9 0.7 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EEQ41375.1 - 0.092 13.2 4.8 0.34 11.4 0.2 3.3 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Orf78 PF06024.12 EEQ41375.1 - 0.11 12.8 0.1 0.36 11.2 0.1 1.9 1 0 0 1 1 1 0 Orf78 (ac78) Syntaxin PF00804.25 EEQ41375.1 - 0.13 11.9 13.8 0.021 14.5 8.3 2.3 2 1 0 2 2 2 0 Syntaxin UPF0242 PF06785.11 EEQ41375.1 - 0.25 11.4 5.6 1.4 9.0 0.0 2.7 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Mer2 PF09074.10 EEQ41375.1 - 0.97 9.2 7.3 0.12 12.2 0.9 2.1 1 1 1 2 2 2 0 Mer2 CENP-F_leu_zip PF10473.9 EEQ41375.1 - 1.1 9.2 6.8 9 6.3 2.4 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LTXXQ PF07813.12 EEQ41375.1 - 4.8 7.9 9.3 0.37 11.5 1.3 2.6 2 1 0 2 2 2 0 LTXXQ motif family protein TolA_bind_tri PF16331.5 EEQ41375.1 - 7.1 6.8 16.2 1.4 9.1 4.2 3.7 2 2 1 3 3 3 0 TolA binding protein trimerisation LPP PF04728.13 EEQ41375.1 - 7.1 7.1 10.2 15 6.1 0.2 3.9 3 2 1 4 4 4 0 Lipoprotein leucine-zipper DNA_pol_B PF00136.21 EEQ41376.1 - 1.2e-118 396.7 0.9 1.6e-118 396.4 0.9 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EEQ41376.1 - 3.7e-62 209.4 2.5 6.2e-62 208.6 2.5 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EEQ41376.1 - 2.4e-37 128.8 0.0 4e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EEQ41376.1 - 5.8e-20 71.1 9.4 1.4e-19 69.9 9.4 1.7 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EEQ41376.1 - 0.016 14.1 0.0 0.055 12.3 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 EEQ41376.1 - 0.064 11.8 0.1 0.1 11.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Glyoxalase PF00903.25 EEQ41377.1 - 2e-13 50.6 0.0 1.3e-09 38.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EEQ41377.1 - 7.9e-05 22.9 0.2 0.53 10.5 0.2 3.2 3 0 0 3 3 3 2 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 EEQ41377.1 - 8.3e-05 22.8 0.0 0.001 19.3 0.0 2.6 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SNF5 PF04855.12 EEQ41378.1 - 1.1e-48 166.2 0.3 4.8e-29 101.8 0.0 2.7 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Cys_Met_Meta_PP PF01053.20 EEQ41379.1 - 1.1e-63 215.0 0.0 2.5e-63 213.9 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Presenilin PF01080.17 EEQ41380.1 - 4.1 6.1 7.4 4.7 5.9 7.4 1.1 1 0 0 1 1 1 0 Presenilin Uricase PF01014.18 EEQ41381.1 - 1.9e-63 212.5 1.3 7.9e-33 113.5 0.3 2.0 2 0 0 2 2 2 2 Uricase RNB PF00773.19 EEQ41382.1 - 1.9e-54 185.2 0.8 7.9e-54 183.2 0.1 2.3 2 0 0 2 2 2 1 RNB domain RSN1_7TM PF02714.15 EEQ41383.1 - 1.3e-89 300.2 23.3 1.3e-89 300.2 23.3 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EEQ41383.1 - 2e-41 141.3 1.1 2e-41 141.3 1.1 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EEQ41383.1 - 6e-30 104.8 1.5 6e-30 104.8 1.5 1.7 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EEQ41383.1 - 1.6e-25 89.1 0.4 4.6e-25 87.6 0.4 1.8 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Phage_holin_8 PF16931.5 EEQ41383.1 - 0.25 11.3 6.7 0.19 11.7 1.4 3.2 2 1 1 3 3 3 0 Putative phage holin Pyrophosphatase PF00719.19 EEQ41384.1 - 4.1e-51 173.0 0.0 5.5e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Thioredoxin_10 PF17991.1 EEQ41384.1 - 0.014 15.9 0.1 0.43 11.1 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin like C-terminal domain Nup188 PF10487.9 EEQ41385.1 - 2.6e-296 985.4 19.4 5e-296 984.5 19.4 1.5 1 0 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 EEQ41385.1 - 6.7e-20 71.2 2.0 1.7e-19 69.9 2.0 1.6 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain GHMP_kinases_N PF00288.26 EEQ41386.1 - 1.7e-15 57.0 2.4 4.7e-15 55.6 2.4 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EEQ41386.1 - 7.1e-06 26.3 0.1 7.1e-06 26.3 0.1 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EEQ41386.1 - 0.00055 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Mtc PF03820.17 EEQ41387.1 - 3.1e-121 404.2 0.1 3.5e-121 404.0 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier ACPS PF01648.20 EEQ41388.1 - 7e-16 58.4 0.0 7.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EEQ41388.1 - 0.0096 16.0 0.2 0.14 12.3 0.2 2.1 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase N-terminal domain GMP_synt_C PF00958.22 EEQ41389.1 - 2.1e-44 149.5 0.2 4.8e-44 148.4 0.2 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 EEQ41389.1 - 1.4e-41 142.4 0.0 2.2e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 EEQ41389.1 - 5.9e-09 35.4 0.1 2.8e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EEQ41389.1 - 5.7e-07 29.5 1.2 8.6e-06 25.7 0.7 2.6 2 1 0 2 2 2 1 Peptidase C26 QueC PF06508.13 EEQ41389.1 - 0.0055 16.2 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC ThiI PF02568.14 EEQ41389.1 - 0.04 13.5 0.0 0.088 12.4 0.0 1.5 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 EEQ41389.1 - 0.042 12.7 0.1 0.086 11.6 0.1 1.5 1 0 0 1 1 1 0 tRNA methyl transferase WD40 PF00400.32 EEQ41390.1 - 3.2e-25 87.9 5.8 1.2e-05 25.9 0.2 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat NLE PF08154.12 EEQ41390.1 - 4.7e-23 81.5 0.1 7.9e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EEQ41390.1 - 7.8e-08 31.4 1.6 0.0011 17.7 0.9 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EEQ41390.1 - 9.8e-05 22.6 0.6 0.4 11.0 0.0 3.9 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain N2227 PF07942.12 EEQ41391.1 - 5.3e-41 140.6 0.0 4.6e-28 98.2 0.0 2.2 2 0 0 2 2 2 2 N2227-like protein DUF913 PF06025.12 EEQ41391.1 - 2.5e-05 23.5 1.0 4.3e-05 22.7 1.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EEQ41391.1 - 0.00045 19.1 0.5 0.00057 18.8 0.5 1.1 1 0 0 1 1 1 1 Presenilin RR_TM4-6 PF06459.12 EEQ41391.1 - 0.0016 18.3 2.3 0.0023 17.8 2.3 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 EEQ41391.1 - 0.0022 17.8 4.9 0.0038 17.0 4.9 1.4 1 0 0 1 1 1 1 Coilin N-terminus CobT PF06213.12 EEQ41391.1 - 0.0055 16.1 5.4 0.0092 15.4 5.4 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 EEQ41391.1 - 0.021 13.2 6.2 0.031 12.6 6.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SAPS PF04499.15 EEQ41391.1 - 0.049 12.4 0.7 0.063 12.1 0.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Zip PF02535.22 EEQ41391.1 - 0.077 12.2 0.9 0.11 11.7 0.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 EEQ41391.1 - 0.11 11.3 2.4 0.15 10.8 2.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 EEQ41391.1 - 0.11 12.7 1.6 0.19 11.9 1.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 EEQ41391.1 - 0.18 12.3 2.6 0.29 11.5 2.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 SUFU_C PF12470.8 EEQ41391.1 - 0.19 11.8 2.3 0.35 10.9 1.5 1.7 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain SpoIIIAH PF12685.7 EEQ41391.1 - 0.51 10.1 9.2 0.88 9.4 9.2 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein RP-C_C PF11800.8 EEQ41391.1 - 0.77 9.8 6.3 1.4 8.9 6.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region NPR3 PF03666.13 EEQ41391.1 - 1.2 7.8 7.0 1.8 7.2 7.0 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 EEQ41391.1 - 2.1 8.0 3.7 3.4 7.4 3.7 1.2 1 0 0 1 1 1 0 Connexin Afi1 PF07792.12 EEQ41391.1 - 2.9 8.4 7.6 6.3 7.3 7.6 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PPTA PF01239.22 EEQ41392.1 - 3e-41 138.0 16.0 4.8e-09 35.6 0.5 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat YfhD PF14151.6 EEQ41392.1 - 0.19 11.9 1.6 0.24 11.6 0.3 1.8 2 0 0 2 2 2 0 YfhD-like protein PSCyt2 PF07583.11 EEQ41392.1 - 0.69 9.8 6.7 0.43 10.5 0.5 3.1 3 1 0 4 4 4 0 Protein of unknown function (DUF1549) SHE3 PF17078.5 EEQ41393.1 - 2.9e-60 203.8 24.3 4.4e-60 203.2 24.3 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 EEQ41393.1 - 0.0011 19.1 0.7 0.0011 19.1 0.7 4.2 4 2 0 4 4 3 1 bZIP transcription factor GAS PF13851.6 EEQ41393.1 - 0.0015 18.0 28.4 0.0067 15.8 9.1 2.8 2 1 1 3 3 3 2 Growth-arrest specific micro-tubule binding DUF4618 PF15397.6 EEQ41393.1 - 0.002 17.6 10.9 0.002 17.6 10.9 2.6 1 1 2 3 3 3 1 Domain of unknown function (DUF4618) KASH_CCD PF14662.6 EEQ41393.1 - 0.0034 17.2 22.5 0.007 16.2 9.1 2.6 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 EEQ41393.1 - 0.048 13.1 28.4 0.28 10.6 19.3 3.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 UPF0242 PF06785.11 EEQ41393.1 - 0.36 10.9 31.0 23 5.0 23.3 3.5 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Lebercilin PF15619.6 EEQ41393.1 - 0.58 9.8 28.4 0.23 11.1 21.2 2.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.18 EEQ41393.1 - 0.96 9.7 21.6 2.5 8.4 0.6 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper Mt_ATP-synt_D PF05873.12 EEQ41393.1 - 1.5 8.7 10.9 0.4 10.5 3.1 2.8 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Spc7 PF08317.11 EEQ41393.1 - 1.8 7.4 30.2 0.46 9.3 12.1 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein Cnn_1N PF07989.11 EEQ41393.1 - 1.8 8.8 19.6 4.2 7.6 1.5 4.4 2 1 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 EEQ41393.1 - 3.5 7.7 14.9 6 6.9 0.8 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 EEQ41393.1 - 4.7 7.4 31.2 9.5 6.4 6.5 3.6 1 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 EEQ41393.1 - 4.9 7.0 19.0 0.74 9.6 0.7 4.4 2 1 2 4 4 4 0 Septum formation initiator ERM PF00769.19 EEQ41393.1 - 5 6.9 30.0 22 4.7 0.3 2.9 2 1 0 2 2 2 0 Ezrin/radixin/moesin family TMCO5 PF14992.6 EEQ41393.1 - 5.9 6.4 19.3 1.8 8.1 13.4 2.3 1 1 1 2 2 2 0 TMCO5 family Tup_N PF08581.10 EEQ41393.1 - 6.4 7.2 13.1 1.9 8.9 2.8 3.9 3 2 1 4 4 4 0 Tup N-terminal FlaC_arch PF05377.11 EEQ41393.1 - 6.4 7.2 10.5 13 6.3 0.0 4.5 4 3 2 6 6 5 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 EEQ41393.1 - 7.4 5.8 24.0 0.056 12.7 5.2 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 EEQ41393.1 - 7.8 6.9 27.7 29 5.0 1.1 3.0 1 1 2 3 3 3 0 Fez1 Cep57_CLD_2 PF14197.6 EEQ41393.1 - 8.8 6.5 25.4 4 7.6 0.5 4.4 3 1 1 4 4 4 0 Centrosome localisation domain of PPC89 DUF4795 PF16043.5 EEQ41393.1 - 9 5.8 25.4 8.6 5.9 4.6 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4795) WD40 PF00400.32 EEQ41394.1 - 0.0038 18.0 0.1 5.7 8.0 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat PQQ_3 PF13570.6 EEQ41394.1 - 0.0065 16.9 0.1 1.1 9.9 0.0 3.5 3 0 0 3 3 3 1 PQQ-like domain Aminotran_5 PF00266.19 EEQ41395.1 - 3.1e-24 85.7 0.0 3.6e-24 85.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EEQ41395.1 - 5.1e-05 22.6 0.1 0.00011 21.5 0.2 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DnaJ PF00226.31 EEQ41396.1 - 6.2e-21 74.3 2.2 6.2e-21 74.3 2.2 2.2 3 0 0 3 3 3 1 DnaJ domain Vps51 PF08700.11 EEQ41396.1 - 0.071 13.2 7.1 0.17 12.0 0.1 2.9 3 1 0 3 3 3 0 Vps51/Vps67 Mit_KHE1 PF10173.9 EEQ41396.1 - 0.37 10.9 6.8 0.53 10.3 6.2 1.5 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related TAF8_C PF10406.9 EEQ41396.1 - 1.3 9.7 5.0 0.37 11.4 1.3 2.1 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term CarD_CdnL_TRCF PF02559.16 EEQ41396.1 - 3.5 8.4 6.7 0.37 11.5 0.6 2.3 2 0 0 2 2 2 0 CarD-like/TRCF domain TOPRIM_C PF16898.5 EEQ41397.1 - 2.2e-45 154.1 1.2 5.3e-45 152.8 0.1 2.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EEQ41397.1 - 9.8e-25 87.0 5.9 1.9e-24 86.1 5.9 1.4 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EEQ41397.1 - 8e-15 55.3 0.1 2.3e-14 53.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EEQ41397.1 - 6.8e-08 32.7 0.0 3.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 Toprim domain Sulfatase PF00884.23 EEQ41397.1 - 0.024 14.0 0.0 0.064 12.6 0.0 1.6 2 0 0 2 2 2 0 Sulfatase STPPase_N PF16891.5 EEQ41397.1 - 1.4 9.4 5.2 1.2 9.7 1.0 2.9 3 0 0 3 3 3 0 Serine-threonine protein phosphatase N-terminal domain DNA_topoisoIV PF00521.20 EEQ41398.1 - 5.9e-48 163.8 0.0 6.9e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_topoisoIV PF00521.20 EEQ41399.1 - 6.5e-08 31.9 1.5 8.1e-08 31.6 1.5 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A PolyA_pol_arg_C PF12626.7 EEQ41399.1 - 0.14 12.2 2.3 0.32 11.0 2.3 1.7 1 0 0 1 1 1 0 Polymerase A arginine-rich C-terminus Glyco_trans_1_2 PF13524.6 EEQ41399.1 - 0.17 12.3 0.7 0.39 11.1 0.1 1.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Myb_DNA-bind_6 PF13921.6 EEQ41400.1 - 0.033 14.4 0.8 0.062 13.6 0.8 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Rdx PF10262.9 EEQ41402.1 - 2.1e-23 82.3 0.0 2.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Rdx family DUF3716 PF12511.8 EEQ41402.1 - 0.041 13.9 0.7 9.2 6.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3716) KSHV_K1 PF11049.8 EEQ41402.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Glycoprotein K1 of Kaposi's sarcoma-associated herpes virus GATA PF00320.27 EEQ41403.1 - 2.6e-16 58.9 5.4 4.5e-16 58.2 5.4 1.4 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 EEQ41403.1 - 2.9e-07 30.2 5.0 6e-07 29.2 5.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 EEQ41403.1 - 0.034 13.7 0.2 0.06 12.9 0.2 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding zf-LSD1 PF06943.12 EEQ41403.1 - 0.24 11.3 1.4 0.49 10.3 1.4 1.5 1 0 0 1 1 1 0 LSD1 zinc finger SWIRM-assoc_2 PF16496.5 EEQ41404.1 - 0.033 13.1 1.9 0.038 12.9 1.9 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CUE PF02845.16 EEQ41405.1 - 8.1e-10 38.2 0.0 1.3e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain Vfa1 PF08432.10 EEQ41405.1 - 1.4 9.2 23.2 6.3 7.1 0.1 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 EEQ41405.1 - 2.4 6.8 19.5 6.1 5.5 0.2 2.1 2 0 0 2 2 2 0 Presenilin Asp PF00026.23 EEQ41406.1 - 1.1e-11 44.8 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease GyrI-like PF06445.15 EEQ41406.1 - 0.091 13.1 0.0 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 GyrI-like small molecule binding domain GATA PF00320.27 EEQ41407.1 - 3e-15 55.5 4.5 4.9e-15 54.8 4.5 1.4 1 0 0 1 1 1 1 GATA zinc finger Trypan_PARP PF05887.11 EEQ41407.1 - 0.052 13.5 2.4 0.092 12.7 0.0 2.1 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Nudix_N_2 PF14803.6 EEQ41407.1 - 0.069 13.1 2.0 0.15 12.0 2.0 1.5 1 0 0 1 1 1 0 Nudix N-terminal Hydrolase_6 PF13344.6 EEQ41408.1 - 7.8e-25 86.9 0.0 1.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EEQ41408.1 - 6.9e-22 77.3 0.0 3.7e-21 74.9 0.0 2.1 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EEQ41408.1 - 0.024 14.9 0.0 3.3 7.9 0.0 3.1 2 1 2 4 4 4 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EEQ41408.1 - 0.043 13.9 0.0 0.7 10.0 0.0 2.7 3 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase TP_methylase PF00590.20 EEQ41409.1 - 1.2e-46 159.4 0.1 2.3e-46 158.4 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EEQ41409.1 - 9.2e-12 45.3 0.0 1.9e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 EEQ41409.1 - 8.9e-07 28.3 0.0 1.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 EEQ41409.1 - 0.0012 18.4 0.0 0.04 13.5 0.0 2.9 2 1 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Nro1 PF12753.7 EEQ41410.1 - 3.5e-165 550.0 20.7 3.9e-165 549.8 20.7 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 TPR_19 PF14559.6 EEQ41410.1 - 0.12 12.9 1.9 1.5 9.4 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-AN1 PF01428.16 EEQ41411.1 - 7.1e-11 42.1 6.1 7.1e-11 42.1 6.1 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Ubiquitin_4 PF18036.1 EEQ41411.1 - 0.00057 19.9 0.0 0.63 10.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin-like domain Transp_Tc5_C PF04236.15 EEQ41411.1 - 0.0091 16.3 1.4 0.017 15.5 1.4 1.5 1 0 0 1 1 1 1 Tc5 transposase C-terminal domain ubiquitin PF00240.23 EEQ41411.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin family Acyltransferase PF01553.21 EEQ41412.1 - 5.2e-13 48.8 0.0 3.1e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 Acyltransferase GlutR_dimer PF00745.20 EEQ41412.1 - 0.019 15.4 0.0 0.073 13.5 0.0 1.9 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain MCM_N PF14551.6 EEQ41412.1 - 0.065 13.8 0.4 0.52 10.9 0.1 2.6 2 0 0 2 2 2 0 MCM N-terminal domain TRAPP PF04051.16 EEQ41413.1 - 1.1e-24 86.8 0.0 1.3e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component FA_hydroxylase PF04116.13 EEQ41414.1 - 1.8e-25 89.8 3.5 1.8e-25 89.8 3.5 2.3 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Wzy_C_2 PF11846.8 EEQ41414.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal Methyltransf_11 PF08241.12 EEQ41415.1 - 8.3e-19 68.0 0.0 1.5e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ41415.1 - 7.5e-17 61.8 0.0 1.9e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ41415.1 - 1.3e-11 44.6 0.0 2.1e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ41415.1 - 2.1e-10 41.2 0.0 4.8e-10 40.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EEQ41415.1 - 2.4e-09 36.9 0.0 3.6e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EEQ41415.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EEQ41415.1 - 0.00073 19.5 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EEQ41415.1 - 0.0023 17.1 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 EEQ41415.1 - 0.0066 16.2 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EEQ41415.1 - 0.0078 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EEQ41415.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EEQ41415.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CMAS PF02353.20 EEQ41415.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_PK PF05891.12 EEQ41415.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase PRANC PF09372.10 EEQ41415.1 - 0.17 12.3 1.2 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 PRANC domain PrmA PF06325.13 EEQ41415.1 - 0.23 10.8 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pirin_C PF05726.13 EEQ41416.1 - 2.7e-20 72.6 0.0 4.4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Pirin PF02678.16 EEQ41416.1 - 0.0064 16.5 0.1 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Pirin CDC27 PF09507.10 EEQ41417.1 - 6.4e-15 55.5 18.0 3.6e-09 36.5 8.2 2.4 2 1 0 2 2 2 2 DNA polymerase subunit Cdc27 GREB1 PF15782.5 EEQ41421.1 - 0.07 10.2 3.2 0.092 9.9 3.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 EEQ41423.1 - 4.6e-64 216.3 0.0 5.7e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41423.1 - 1.3e-37 129.5 0.0 1.8e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EEQ41423.1 - 9e-05 21.4 0.4 0.00016 20.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EEQ41423.1 - 0.022 14.1 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EEQ41423.1 - 0.037 13.6 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 RIO1 family zinc_ribbon_2 PF13240.6 EEQ41424.1 - 0.002 17.8 1.3 0.002 17.8 1.3 4.5 7 0 0 7 7 7 1 zinc-ribbon domain C1_1 PF00130.22 EEQ41424.1 - 0.022 14.6 23.7 0.78 9.7 1.6 4.8 3 2 1 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 EEQ41424.1 - 1 9.4 32.3 0.077 13.0 10.7 3.9 2 2 1 3 3 3 0 zinc-ribbons TPR_12 PF13424.6 EEQ41427.1 - 0.00068 19.9 10.4 0.15 12.4 0.1 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EEQ41427.1 - 0.0026 17.7 11.0 0.69 10.2 0.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EEQ41427.1 - 0.025 14.4 13.0 0.93 9.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EEQ41427.1 - 0.047 14.4 0.2 0.047 14.4 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EEQ41427.1 - 0.2 12.6 2.3 5.2 8.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Adap_comp_sub PF00928.21 EEQ41428.1 - 4.3e-13 49.2 0.0 7.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EEQ41428.1 - 3.5e-08 33.5 0.2 6.5e-08 32.6 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EEQ41428.1 - 0.029 13.8 0.1 0.11 11.9 0.1 1.9 1 1 0 1 1 1 0 Muniscin C-terminal mu homology domain PDEase_II PF02112.15 EEQ41429.1 - 2.6e-61 207.6 0.0 7.1e-61 206.2 0.0 1.6 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 EEQ41429.1 - 6.5e-08 32.3 0.0 9.5e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EEQ41429.1 - 0.0069 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Proteasome PF00227.26 EEQ41430.1 - 1.1e-25 90.2 0.0 1.6e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF4836 PF16120.5 EEQ41430.1 - 0.086 11.8 0.1 0.32 9.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4836) DUF410 PF04190.13 EEQ41431.1 - 8.1e-71 238.8 0.6 1e-70 238.5 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) NUDIX PF00293.28 EEQ41432.1 - 5.9e-13 49.0 0.0 8.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain EF-hand_6 PF13405.6 EEQ41433.1 - 1.2e-06 27.9 0.1 0.041 13.8 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EEQ41433.1 - 2.8e-05 24.5 0.6 2.8e-05 24.5 0.6 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EEQ41433.1 - 7.2e-05 22.1 0.0 0.00018 20.8 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EEQ41433.1 - 8e-05 21.9 0.9 0.00025 20.3 0.0 2.4 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EEQ41433.1 - 0.027 14.3 0.3 0.077 12.9 0.2 1.9 2 0 0 2 2 2 0 EF-hand domain pair Glyco_transf_29 PF00777.18 EEQ41433.1 - 5 6.4 8.5 3.8 6.8 6.6 1.7 2 0 0 2 2 2 0 Glycosyltransferase family 29 (sialyltransferase) CX9C PF16860.5 EEQ41435.1 - 1.3e-24 85.9 5.3 1.9e-17 62.9 2.2 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EEQ41435.1 - 2.3e-08 34.0 6.5 0.00075 19.6 0.8 2.6 2 2 0 2 2 2 2 CHCH domain COX6B PF02297.17 EEQ41435.1 - 0.023 14.9 3.2 0.32 11.3 3.2 2.2 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb PAN_3 PF08277.12 EEQ41435.1 - 0.033 14.0 0.2 0.062 13.1 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain NDUF_B7 PF05676.13 EEQ41435.1 - 0.058 13.1 4.0 0.095 12.4 0.6 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX17 PF05051.13 EEQ41435.1 - 1.2 9.5 7.9 6.2 7.3 1.0 3.3 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GCK PF07802.11 EEQ41435.1 - 1.8 9.0 5.0 5.7 7.4 0.3 3.0 1 1 0 2 2 2 0 GCK domain DUF3128 PF11326.8 EEQ41435.1 - 4.3 7.8 5.7 1.3e+02 3.1 4.1 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Peptidase_S24 PF00717.23 EEQ41436.1 - 9.6e-10 38.3 0.1 2.6e-09 36.9 0.1 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EEQ41436.1 - 7.6e-06 25.8 0.0 0.012 15.4 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 LicD PF04991.13 EEQ41437.1 - 2.7e-23 83.3 1.2 5.1e-23 82.4 0.3 1.8 2 0 0 2 2 2 1 LicD family Folliculin PF11704.8 EEQ41438.1 - 1.5e-42 145.6 0.0 5.4e-41 140.5 0.0 2.0 1 1 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport APG6 PF04111.12 EEQ41439.1 - 2.7e-05 24.2 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Apg6 BARA domain Atg14 PF10186.9 EEQ41439.1 - 0.0001 21.6 6.1 0.023 13.8 0.1 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EEQ41439.1 - 0.05 13.6 1.0 0.098 12.7 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) VPS38 PF17649.1 EEQ41439.1 - 0.078 11.8 0.1 0.078 11.8 0.1 2.9 2 1 0 2 2 2 0 Vacuolar protein sorting 38 Spc7 PF08317.11 EEQ41439.1 - 0.1 11.4 3.6 0.19 10.6 3.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 EEQ41439.1 - 0.58 10.7 4.2 0.13 12.8 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 SRP1_TIP1 PF00660.17 EEQ41440.1 - 9.6e-22 76.9 0.1 1.3e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family PAGK PF15284.6 EEQ41441.1 - 0.0058 16.5 0.4 0.0058 16.5 0.4 1.8 2 0 0 2 2 2 1 Phage-encoded virulence factor EVI2A PF05399.11 EEQ41441.1 - 0.11 12.0 11.4 0.13 11.9 11.4 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Arch_flagellin PF01917.16 EEQ41441.1 - 0.13 12.4 11.5 0.18 12.0 11.4 1.3 1 1 0 1 1 1 0 Archaebacterial flagellin Zip PF02535.22 EEQ41441.1 - 0.17 11.1 6.5 0.19 10.9 6.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EEQ41441.1 - 0.24 10.1 11.2 0.28 9.9 11.2 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EEQ41441.1 - 0.39 9.7 6.5 0.44 9.5 6.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 EEQ41441.1 - 3.6 5.6 15.2 4.2 5.4 15.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Utp14 PF04615.13 EEQ41441.1 - 3.6 6.0 17.2 4.1 5.8 17.2 1.0 1 0 0 1 1 1 0 Utp14 protein Conotoxin PF02950.17 EEQ41441.1 - 3.8 8.6 5.5 3.3 8.8 0.2 2.2 1 1 0 2 2 2 0 Conotoxin NPR3 PF03666.13 EEQ41441.1 - 5.7 5.6 13.4 7.6 5.2 13.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Apt1 PF10351.9 EEQ41441.1 - 6.2 5.6 22.8 7.5 5.3 22.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SURF2 PF05477.11 EEQ41441.1 - 7.6 6.2 11.8 9.7 5.8 11.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) KIAA1328 PF15369.6 EEQ41441.1 - 8.5 6.1 9.3 9.7 5.9 9.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 SAPS PF04499.15 EEQ41441.1 - 8.6 5.0 9.2 10 4.8 9.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein WD40 PF00400.32 EEQ41442.1 - 1.1e-52 174.8 16.0 3e-09 37.3 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EEQ41442.1 - 1e-46 158.4 0.2 1.7e-46 157.7 0.2 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EEQ41442.1 - 7.1e-13 48.7 0.0 0.087 13.1 0.0 5.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EEQ41442.1 - 2.3e-07 30.5 0.1 6.5e-07 29.1 0.1 1.9 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EEQ41442.1 - 1.6e-05 23.8 0.2 0.086 11.5 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EEQ41442.1 - 0.0002 20.4 0.0 4 6.3 0.0 4.2 3 2 1 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EEQ41442.1 - 0.0023 17.3 0.0 7.4 5.8 0.0 3.3 3 0 0 3 3 3 1 WD40-like domain eIF2A PF08662.11 EEQ41442.1 - 0.0039 17.1 0.0 0.63 9.9 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EEQ41442.1 - 0.022 14.7 0.1 7.1 6.7 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat nos_propeller PF18764.1 EEQ41442.1 - 0.024 14.5 0.0 6.9 6.7 0.0 2.7 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat GPI2 PF06432.11 EEQ41443.1 - 2.4e-74 250.3 17.5 2.9e-74 250.0 17.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase FA_desaturase PF00487.24 EEQ41443.1 - 6 6.6 10.3 2.6 7.8 5.1 2.2 1 1 1 2 2 2 0 Fatty acid desaturase DUF5315 PF17242.2 EEQ41444.1 - 2.1e-19 69.1 5.1 2.1e-19 69.1 5.1 1.9 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) Ribosomal_L37 PF08561.10 EEQ41444.1 - 0.11 13.1 6.0 0.16 12.5 6.0 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 SlyX PF04102.12 EEQ41444.1 - 7.2 7.3 11.8 3.6 8.3 0.8 3.0 3 0 0 3 3 3 0 SlyX Hexokinase_2 PF03727.16 EEQ41446.1 - 2.5e-77 259.5 0.0 4.7e-77 258.6 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Hexokinase_1 PF00349.21 EEQ41446.1 - 1.6e-72 243.6 0.0 2.3e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Rpr2 PF04032.16 EEQ41447.1 - 2.4e-22 79.0 3.8 3e-22 78.7 3.8 1.1 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain ADD_ATRX PF17981.1 EEQ41447.1 - 0.19 11.6 3.1 0.19 11.6 0.4 2.1 2 0 0 2 2 2 0 Cysteine Rich ADD domain XPG_I PF00867.18 EEQ41448.1 - 3.5e-28 97.8 0.1 6.3e-28 97.0 0.1 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EEQ41448.1 - 2e-17 63.5 0.0 4e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EEQ41448.1 - 2.7e-07 31.1 0.1 4e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EEQ41448.1 - 0.021 15.4 2.3 0.23 12.1 0.0 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix domain HHH_2 PF12826.7 EEQ41448.1 - 0.036 14.2 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif XPG_I_2 PF12813.7 EEQ41448.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing Nucleoporin2 PF04096.14 EEQ41449.1 - 2.3e-46 157.6 0.0 4.4e-46 156.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EEQ41449.1 - 4.1e-31 107.7 366.7 8.9e-12 45.7 41.5 10.5 2 2 8 10 10 10 9 Nucleoporin FG repeat region AP_endonuc_2 PF01261.24 EEQ41450.1 - 2.2e-34 118.8 0.0 3.2e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel CDI PF02234.19 EEQ41450.1 - 0.085 13.1 0.0 0.42 10.8 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor DUF16 PF01519.16 EEQ41450.1 - 9.1 6.8 9.7 14 6.2 6.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Telomere_reg-2 PF10193.9 EEQ41452.1 - 9.7e-29 100.0 0.8 3.4e-28 98.2 0.8 2.1 1 0 0 1 1 1 1 Telomere length regulation protein TFR_dimer PF04253.15 EEQ41454.1 - 7e-27 93.9 0.6 1.2e-26 93.2 0.6 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain NCD1 PF04904.13 EEQ41454.1 - 0.051 13.6 2.1 0.56 10.2 0.0 3.2 4 0 0 4 4 4 0 NAB conserved region 1 (NCD1) PA PF02225.22 EEQ41455.1 - 1e-12 47.9 0.2 2.9e-12 46.4 0.1 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M28 PF04389.17 EEQ41455.1 - 1e-05 25.3 0.0 1.7e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Keratin_B2_2 PF13885.6 EEQ41455.1 - 3.8 7.6 9.5 5.7 7.0 9.5 1.2 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Amidohydro_1 PF01979.20 EEQ41456.1 - 1.1e-26 94.0 0.0 1.5e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EEQ41456.1 - 1.6e-15 57.5 0.0 8.9e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family APP_Cu_bd PF12924.7 EEQ41456.1 - 0.052 14.3 0.8 0.18 12.5 0.1 2.2 3 0 0 3 3 3 0 Copper-binding of amyloid precursor, CuBD Amidohydro_2 PF04909.14 EEQ41456.1 - 0.21 11.4 0.0 0.64 9.7 0.0 1.9 2 1 0 2 2 2 0 Amidohydrolase Zn_clus PF00172.18 EEQ41457.1 - 1e-06 28.7 12.3 1e-06 28.7 12.3 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EEQ41457.1 - 1.6e-06 27.2 3.6 0.0011 17.8 0.1 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain Transp_cyt_pur PF02133.15 EEQ41460.1 - 4e-137 457.6 41.5 4.9e-137 457.3 41.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Peptidase_M20 PF01546.28 EEQ41461.1 - 5.2e-32 111.2 0.0 8.1e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EEQ41461.1 - 2.1e-05 24.4 0.0 5.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EEQ41461.1 - 0.011 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Ammonium_transp PF00909.21 EEQ41462.1 - 1.9e-89 300.1 25.3 2.4e-89 299.8 25.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Transp_cyt_pur PF02133.15 EEQ41463.1 - 1.4e-56 192.2 28.1 1.6e-56 192.0 28.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Asp PF00026.23 EEQ41464.1 - 2.5e-08 33.7 0.1 4.2e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease EVI2A PF05399.11 EEQ41464.1 - 4.8 6.7 6.8 7.6 6.1 6.8 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Hyphal_reg_CWP PF11765.8 EEQ41465.1 - 1.4e-77 260.8 10.0 2.4e-77 260.1 10.0 1.3 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF4272 PF14094.6 EEQ41465.1 - 0.27 10.4 0.0 0.41 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) CDC48_2 PF02933.17 EEQ41466.1 - 2.9e-07 30.2 16.5 0.029 14.1 0.3 4.1 1 1 2 4 4 4 4 Cell division protein 48 (CDC48), domain 2 DUF4245 PF14030.6 EEQ41466.1 - 0.031 14.3 6.3 0.062 13.3 6.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4245) SPATA48 PF15073.6 EEQ41466.1 - 3 8.2 9.8 2.7 8.3 0.9 2.5 1 1 2 3 3 3 0 Spermatogenesis-associated protein 48 Syntaxin_2 PF14523.6 EEQ41467.1 - 1.7e-14 54.0 8.8 0.22 11.9 0.1 6.0 1 1 5 6 6 6 5 Syntaxin-like protein Lactococcin_972 PF09683.10 EEQ41467.1 - 3.9e-09 36.9 8.9 10 6.7 0.0 6.4 6 0 0 6 6 6 5 Bacteriocin (Lactococcin_972) Slp PF03843.13 EEQ41467.1 - 4.4e-07 29.4 15.5 1.6 8.1 0.1 5.4 1 1 3 5 5 5 5 Outer membrane lipoprotein Slp family DUF4418 PF14387.6 EEQ41467.1 - 1.8 8.8 14.6 1.3e+02 2.8 0.0 5.8 5 1 0 6 6 6 0 Domain of unknown function (DUF4418) Defensin_2 PF01097.18 EEQ41467.1 - 2.1 8.3 26.6 47 4.0 0.1 7.8 7 0 0 7 7 7 0 Arthropod defensin MSL2-CXC PF16682.5 EEQ41467.1 - 3.1 8.0 34.7 23 5.2 0.6 6.9 7 0 0 7 7 7 0 CXC domain of E3 ubiquitin-protein ligase MSL2 Babuvirus_MP PF07234.11 EEQ41468.1 - 0.00041 20.5 2.7 67 3.7 0.0 6.4 2 2 5 8 8 8 0 Movement and RNA silencing protein Endonuc-FokI_C PF09254.11 EEQ41468.1 - 0.0008 18.7 7.0 12 5.1 0.0 6.7 1 1 8 9 9 9 1 Restriction endonuclease FokI, C terminal Ribosomal_S27e PF01667.17 EEQ41468.1 - 0.0031 17.2 32.9 3.9 7.3 0.2 8.3 9 0 0 9 9 9 5 Ribosomal protein S27 LDB19 PF13002.7 EEQ41468.1 - 0.023 14.4 1.5 24 4.6 0.0 3.8 1 1 3 4 4 4 0 Arrestin_N terminal like DUF1610 PF07754.11 EEQ41468.1 - 0.057 13.4 13.4 2.9 7.9 0.1 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1610) Lar_restr_allev PF14354.6 EEQ41468.1 - 0.11 12.8 4.4 7.7 7.0 0.0 4.7 5 1 0 5 5 5 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 EEQ41468.1 - 0.36 10.3 15.0 34 4.0 0.1 6.0 6 0 0 6 6 6 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 EEQ41468.1 - 0.9 9.5 21.3 17 5.4 0.1 6.6 7 0 0 7 7 7 0 PhnA Zinc-Ribbon zinc_ribbon_6 PF14599.6 EEQ41468.1 - 2.1 8.4 26.9 15 5.7 0.1 8.1 9 0 0 9 9 9 0 Zinc-ribbon Hyphal_reg_CWP PF11765.8 EEQ41469.1 - 1e-74 251.5 8.6 1.4e-74 251.0 8.6 1.1 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal CDC48_2 PF02933.17 EEQ41470.1 - 0.69 9.7 12.5 4.8 7.1 0.7 3.3 2 1 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 NtCtMGAM_N PF16863.5 EEQ41470.1 - 1.1 9.5 6.7 5 7.4 0.3 2.8 1 1 2 3 3 3 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Alliinase_C PF04864.13 EEQ41470.1 - 1.8 7.4 4.8 0.88 8.4 0.5 2.0 1 1 1 2 2 2 0 Allinase nos_propeller_2 PF18793.1 EEQ41471.1 - 0.4 11.1 3.1 71 3.8 0.0 5.8 7 0 0 7 7 7 0 Nitrous oxide reductase propeller repeat 2 Ammonium_transp PF00909.21 EEQ41472.1 - 1.1e-31 109.9 5.3 1.5e-31 109.5 5.3 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family Peptidase_C6 PF00851.18 EEQ41472.1 - 0.086 11.8 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Helper component proteinase Sec_GG PF07549.14 EEQ41472.1 - 0.22 11.0 0.9 0.55 9.8 0.9 1.7 1 0 0 1 1 1 0 SecD/SecF GG Motif Hyphal_reg_CWP PF11765.8 EEQ41473.1 - 2.4e-72 243.7 16.3 2.4e-72 243.7 16.3 1.9 3 0 0 3 3 3 1 Hyphally regulated cell wall protein N-terminal Ribosomal_S27e PF01667.17 EEQ41473.1 - 0.053 13.2 1.5 7 6.4 0.2 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 DUF3060 PF11259.8 EEQ41473.1 - 0.064 13.0 2.3 0.16 11.7 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3060) DUF723 PF05265.13 EEQ41473.1 - 0.45 10.5 4.3 12 5.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF723) Zn-ribbon_8 PF09723.10 EEQ41473.1 - 0.63 10.2 2.2 9.7 6.4 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-LITAF-like PF10601.9 EEQ41473.1 - 5.5 7.3 5.4 22 5.4 0.6 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF4668 PF15701.5 EEQ41474.1 - 0.094 12.5 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) HZS_alpha PF18582.1 EEQ41475.1 - 0.58 10.7 14.4 18 5.9 0.0 6.9 7 0 0 7 7 7 0 Hydrazine synthase alpha subunit middle domain Gln-synt_N_2 PF16952.5 EEQ41476.1 - 0.16 11.8 0.9 1.1 9.1 0.0 2.3 2 1 1 3 3 3 0 Glutamine synthetase N-terminal domain NtCtMGAM_N PF16863.5 EEQ41477.1 - 0.6 10.3 7.9 38 4.5 5.8 2.8 2 1 0 2 2 2 0 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase CDC48_2 PF02933.17 EEQ41477.1 - 1.3 8.8 25.7 11 5.9 0.7 5.9 1 1 2 3 3 3 0 Cell division protein 48 (CDC48), domain 2 ASRT PF07100.11 EEQ41477.1 - 5 7.2 8.0 11 6.1 0.8 3.8 1 1 2 4 4 4 0 Anabaena sensory rhodopsin transducer Hyphal_reg_CWP PF11765.8 EEQ41478.1 - 3.6e-73 246.4 3.4 7.6e-73 245.3 3.4 1.5 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Hyphal_reg_CWP PF11765.8 EEQ41479.1 - 1.4e-71 241.2 10.8 1.4e-71 241.2 10.8 2.0 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal MFS_1 PF07690.16 EEQ41480.1 - 4.7e-18 65.2 42.4 3.5e-11 42.6 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EEQ41481.1 - 1.2e-21 76.9 3.1 2.1e-21 76.2 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ41481.1 - 2.2e-10 40.5 9.2 2.2e-10 40.5 9.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EEQ41482.1 - 2.6e-29 102.3 26.9 4.3e-29 101.5 27.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EEQ41482.1 - 2e-10 40.5 0.8 2e-10 40.5 0.8 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF1298 PF06974.13 EEQ41482.1 - 0.012 15.6 0.4 0.086 12.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1298) 3Beta_HSD PF01073.19 EEQ41483.1 - 4.4e-18 65.3 0.0 7.4e-18 64.5 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EEQ41483.1 - 8.5e-18 64.7 0.0 1.2e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EEQ41483.1 - 5.5e-11 42.7 0.0 9.9e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EEQ41483.1 - 6.2e-11 42.0 0.0 4e-06 26.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EEQ41483.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EEQ41483.1 - 3.1e-05 23.7 0.0 0.0007 19.2 0.0 2.3 2 1 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EEQ41483.1 - 0.00017 20.8 0.0 0.00035 19.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EEQ41483.1 - 0.00029 20.3 0.0 0.00072 19.1 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EEQ41483.1 - 0.069 13.4 0.0 0.55 10.5 0.0 2.3 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 EEQ41484.1 - 8.2e-16 58.2 0.1 2.4e-14 53.4 0.1 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EEQ41484.1 - 1.8e-06 28.1 0.6 3.9e-06 27.0 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EEQ41484.1 - 6.7e-06 25.6 3.0 0.00014 21.2 2.9 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEQ41484.1 - 8.9e-05 21.7 1.1 0.00013 21.2 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EEQ41484.1 - 0.00024 20.6 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EEQ41484.1 - 0.00026 20.2 0.6 0.00039 19.6 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 EEQ41484.1 - 0.00038 20.2 4.0 0.0014 18.3 2.9 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EEQ41484.1 - 0.016 13.9 0.7 0.044 12.5 0.4 1.7 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 EEQ41484.1 - 0.024 14.0 0.2 0.7 9.1 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 EEQ41484.1 - 0.036 12.9 0.9 3.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 EEQ41484.1 - 0.042 13.2 0.1 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EEQ41484.1 - 0.066 13.8 2.1 0.077 13.6 0.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.8 EEQ41485.1 - 5.5e-41 140.7 3.7 8.3e-41 140.1 3.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ41485.1 - 3.1e-13 49.6 38.0 7.6e-07 29.2 17.2 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EEQ41487.1 - 6.3e-12 45.4 1.2 2e-10 40.5 1.2 2.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EEQ41487.1 - 0.00019 21.1 0.2 0.024 14.2 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EEQ41487.1 - 0.00026 21.5 0.1 0.32 11.6 0.0 2.7 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EEQ41487.1 - 0.0008 18.7 0.0 0.86 8.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EEQ41487.1 - 0.0026 18.0 0.0 0.0058 16.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EEQ41487.1 - 0.0033 16.8 0.1 0.017 14.5 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.16 EEQ41487.1 - 0.027 14.1 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 EEQ41487.1 - 0.058 12.8 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EEQ41487.1 - 0.069 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EEQ41487.1 - 0.2 11.7 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-HC2 PF13490.6 EEQ41487.1 - 0.21 11.9 1.3 0.63 10.3 0.2 2.3 2 0 0 2 2 2 0 Putative zinc-finger Abhydrolase_3 PF07859.13 EEQ41488.1 - 1.5e-41 142.6 0.0 2.2e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EEQ41488.1 - 0.0028 16.6 0.1 0.029 13.3 0.1 2.0 1 1 0 1 1 1 1 Carboxylesterase family AXE1 PF05448.12 EEQ41488.1 - 0.0033 16.1 0.0 0.15 10.7 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Mannosyl_trans3 PF11051.8 EEQ41490.1 - 4.1e-61 206.7 0.1 5.5e-61 206.3 0.1 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.20 EEQ41490.1 - 0.019 14.5 0.1 0.22 11.0 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family 8 Pkinase PF00069.25 EEQ41491.1 - 2.5e-44 151.6 0.0 4.8e-44 150.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41491.1 - 1.8e-15 56.9 0.1 7.2e-15 55.0 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EEQ41491.1 - 0.0033 17.1 0.0 0.017 14.7 0.0 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EEQ41491.1 - 0.056 13.4 0.2 0.33 10.8 0.1 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family SDA1 PF05285.12 EEQ41491.1 - 0.069 12.6 25.3 0.099 12.1 25.3 1.3 1 0 0 1 1 1 0 SDA1 DUF21 PF01595.20 EEQ41493.1 - 4e-32 111.3 0.0 6.8e-32 110.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain EIAV_Rev PF11129.8 EEQ41493.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus SRP-alpha_N PF04086.13 EEQ41493.1 - 1.5 8.6 15.7 2.9 7.7 15.7 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NPR3 PF03666.13 EEQ41493.1 - 8.2 5.1 10.4 14 4.3 10.4 1.5 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PI3K_1B_p101 PF10486.9 EEQ41493.1 - 8.5 4.0 13.9 14 3.3 13.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-MIZ PF02891.20 EEQ41494.1 - 2e-08 33.8 1.6 1.5e-06 27.9 0.4 2.3 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EEQ41494.1 - 0.0025 17.6 0.4 0.0066 16.3 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Nop14 PF04147.12 EEQ41494.1 - 0.028 12.6 16.7 0.039 12.2 16.7 1.1 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.15 EEQ41494.1 - 2.4 7.6 10.2 3.8 7.0 10.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF2457 PF10446.9 EEQ41494.1 - 4.3 6.4 24.0 6.7 5.7 24.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.12 EEQ41494.1 - 4.9 6.5 21.3 7.8 5.8 21.3 1.3 1 0 0 1 1 1 0 SDA1 PI3K_1B_p101 PF10486.9 EEQ41494.1 - 9.1 3.9 9.2 13 3.4 9.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit NOA36 PF06524.12 EEQ41494.1 - 9.6 5.4 21.2 18 4.5 21.2 1.4 1 0 0 1 1 1 0 NOA36 protein LtrA PF06772.11 EEQ41495.1 - 7.2e-19 68.2 11.8 8.6e-19 68.0 11.8 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF1430 PF07242.11 EEQ41495.1 - 7.8 6.8 7.9 9.7 6.5 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1430) LtrA PF06772.11 EEQ41496.1 - 8.7e-10 38.3 0.7 1.1e-09 38.0 0.7 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) SNARE PF05739.19 EEQ41498.1 - 0.66 10.0 2.2 1.3 9.1 2.2 1.4 1 0 0 1 1 1 0 SNARE domain MRP-S25 PF13741.6 EEQ41499.1 - 7.5e-92 307.0 6.5 7.5e-92 307.0 6.5 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EEQ41499.1 - 1.1e-07 32.1 0.8 5e-05 23.6 0.1 3.1 1 1 2 3 3 3 2 Mitochondrial ribosomal protein S23 HSA PF07529.13 EEQ41500.1 - 0.06 13.7 0.2 0.17 12.3 0.2 1.7 1 0 0 1 1 1 0 HSA DnaB_2 PF07261.11 EEQ41500.1 - 0.18 11.6 1.0 6.8 6.5 0.1 3.3 3 0 0 3 3 3 0 Replication initiation and membrane attachment NepR PF18557.1 EEQ41500.1 - 0.21 11.3 3.1 2.3 7.9 0.2 2.7 2 0 0 2 2 2 0 Anti-sigma factor NepR Frataxin_Cyay PF01491.16 EEQ41502.1 - 3.2e-36 123.7 0.0 4.1e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain TT_ORF1 PF02956.14 EEQ41503.1 - 0.036 12.8 5.2 0.039 12.6 5.2 1.1 1 0 0 1 1 1 0 TT viral orf 1 GNAT_acetyltr_2 PF13718.6 EEQ41505.1 - 2.2e-98 328.2 0.4 8.9e-98 326.2 0.0 2.2 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EEQ41505.1 - 1.3e-76 257.4 2.1 1.3e-76 257.4 2.1 1.6 1 1 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EEQ41505.1 - 4.3e-66 222.1 0.1 3e-65 219.4 0.0 2.4 2 1 0 2 2 2 1 Helicase DUF1726 PF08351.11 EEQ41505.1 - 1.3e-33 114.8 0.8 3e-33 113.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EEQ41505.1 - 0.00014 21.7 0.0 0.0063 16.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EEQ41505.1 - 0.0022 18.3 0.0 0.15 12.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEQ41505.1 - 0.0085 16.4 0.0 0.053 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Acetyltransf_1 PF00583.25 EEQ41505.1 - 0.15 12.3 0.0 0.66 10.2 0.0 2.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family NDT80_PhoG PF05224.12 EEQ41506.1 - 1e-44 153.0 0.2 2.1e-44 152.0 0.1 1.6 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family zf-C2H2_10 PF16588.5 EEQ41507.1 - 1.1e-11 44.2 7.9 2.5e-11 43.1 7.9 1.6 1 0 0 1 1 1 1 C2H2 zinc-finger ING PF12998.7 EEQ41507.1 - 0.031 14.9 0.2 0.058 14.0 0.2 1.5 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding CcmH PF03918.14 EEQ41507.1 - 0.083 12.2 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein YyzF PF14116.6 EEQ41507.1 - 0.33 11.0 2.7 0.79 9.8 0.2 2.4 2 0 0 2 2 2 0 YyzF-like protein zinc_ribbon_4 PF13717.6 EEQ41507.1 - 0.94 9.5 4.4 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-CCHC PF00098.23 EEQ41507.1 - 4.3 7.6 8.6 0.58 10.3 2.2 2.4 2 0 0 2 2 2 0 Zinc knuckle DUF2616 PF11077.8 EEQ41507.1 - 4.4 7.0 7.3 7.8 6.2 2.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2616) Rft-1 PF04506.13 EEQ41508.1 - 6.6e-138 460.6 24.9 7.5e-138 460.5 24.9 1.0 1 0 0 1 1 1 1 Rft protein CBFD_NFYB_HMF PF00808.23 EEQ41509.1 - 1.5e-25 89.3 0.1 2.4e-25 88.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EEQ41509.1 - 6.3e-05 23.4 4.4 9.7e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EEQ41509.1 - 0.0092 16.0 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EEQ41509.1 - 0.014 15.5 0.1 0.026 14.7 0.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold DUF4770 PF15994.5 EEQ41509.1 - 5.6 7.2 9.0 17 5.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4770) zf-RING_2 PF13639.6 EEQ41511.1 - 5.1e-10 39.5 12.4 8.2e-10 38.9 12.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EEQ41511.1 - 7.3e-08 32.6 6.9 1.2e-07 31.9 6.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EEQ41511.1 - 6e-05 22.8 10.9 0.00012 21.8 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EEQ41511.1 - 7e-05 22.5 8.0 0.00013 21.6 8.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EEQ41511.1 - 0.00037 20.3 8.6 0.00055 19.7 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EEQ41511.1 - 0.00039 20.4 5.0 0.00062 19.8 5.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EEQ41511.1 - 0.011 15.6 10.1 0.019 14.8 10.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EEQ41511.1 - 0.018 15.1 9.3 0.041 13.9 9.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 EEQ41511.1 - 0.021 14.7 10.9 0.054 13.4 10.9 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EEQ41511.1 - 0.033 13.8 7.2 0.055 13.1 7.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EEQ41511.1 - 0.5 10.4 9.8 0.85 9.6 9.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Methyltr_RsmB-F PF01189.17 EEQ41512.1 - 6.4e-42 143.5 1.4 1.5e-41 142.2 0.0 2.4 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EEQ41512.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DDHD PF02862.17 EEQ41512.1 - 0.037 14.2 9.0 0.11 12.7 0.7 2.3 2 0 0 2 2 2 0 DDHD domain RR_TM4-6 PF06459.12 EEQ41512.1 - 0.084 12.7 28.4 0.2 11.4 11.4 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EEQ41512.1 - 0.12 12.8 19.4 1.6 9.2 10.0 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 CCDC53 PF10152.9 EEQ41512.1 - 0.3 11.5 13.9 3.1 8.2 6.4 2.4 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Coilin_N PF15862.5 EEQ41512.1 - 0.37 10.6 24.6 0.51 10.2 10.0 3.1 3 0 0 3 3 3 0 Coilin N-terminus Zip PF02535.22 EEQ41512.1 - 0.68 9.1 8.4 1.8 7.7 1.2 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter SAPS PF04499.15 EEQ41512.1 - 0.77 8.5 11.9 0.33 9.7 1.1 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.11 EEQ41512.1 - 1.9 7.8 16.1 0.027 13.9 0.9 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein DUF5308 PF17233.2 EEQ41512.1 - 2.7 8.2 10.9 0.62 10.3 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5308) Neur_chan_memb PF02932.16 EEQ41512.1 - 5.2 7.1 10.6 3.9 7.5 2.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region UAF_Rrn10 PF05234.11 EEQ41514.1 - 2.1e-05 24.7 0.0 5.2e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 UAF complex subunit Rrn10 Mem_trans PF03547.18 EEQ41514.1 - 0.23 9.8 2.3 0.34 9.2 2.3 1.2 1 0 0 1 1 1 0 Membrane transport protein SDA1 PF05285.12 EEQ41514.1 - 0.32 10.4 7.1 0.35 10.2 7.1 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EEQ41514.1 - 1.6 8.0 13.5 2.6 7.3 13.5 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 EEQ41514.1 - 5.3 5.1 7.9 6.7 4.8 7.9 1.1 1 0 0 1 1 1 0 Nop14-like family HalX PF08663.10 EEQ41515.1 - 5.2 7.5 10.3 8.7 6.7 4.4 2.7 2 0 0 2 2 2 0 HalX domain LON_substr_bdg PF02190.16 EEQ41516.1 - 5.4e-22 78.7 1.9 3.9e-21 75.9 0.0 2.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EEQ41516.1 - 2.1e-21 76.7 0.2 1.6e-20 73.9 0.0 2.4 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EEQ41516.1 - 3.9e-07 30.2 0.0 7.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EEQ41516.1 - 1e-06 29.0 0.0 5.5e-06 26.6 0.0 2.3 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_PrkA PF08298.11 EEQ41516.1 - 5.2e-06 25.6 0.0 9.4e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 EEQ41516.1 - 9.2e-06 25.5 0.0 0.00023 20.9 0.0 2.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EEQ41516.1 - 1.8e-05 25.0 1.0 0.0069 16.7 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EEQ41516.1 - 3.1e-05 24.4 0.1 0.00013 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EEQ41516.1 - 0.00018 21.3 0.0 0.0004 20.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein NTPase_1 PF03266.15 EEQ41516.1 - 0.0005 20.0 0.0 0.054 13.4 0.0 2.5 1 1 1 2 2 2 1 NTPase TIP49 PF06068.13 EEQ41516.1 - 0.001 18.3 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EEQ41516.1 - 0.0038 17.8 1.7 0.006 17.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 EEQ41516.1 - 0.0051 16.2 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EEQ41516.1 - 0.0051 16.1 0.1 0.017 14.4 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_30 PF13604.6 EEQ41516.1 - 0.0095 15.7 0.1 0.025 14.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.6 EEQ41516.1 - 0.0099 15.9 0.2 0.038 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EEQ41516.1 - 0.022 14.7 0.1 0.15 11.9 0.0 2.5 4 0 0 4 4 2 0 NACHT domain AAA_33 PF13671.6 EEQ41516.1 - 0.023 14.9 0.0 0.076 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EEQ41516.1 - 0.025 14.6 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EEQ41516.1 - 0.031 14.8 1.0 0.18 12.3 0.1 2.7 2 1 1 3 3 3 0 ABC transporter AAA_3 PF07726.11 EEQ41516.1 - 0.035 14.0 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EEQ41516.1 - 0.037 14.4 2.1 0.069 13.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EEQ41516.1 - 0.055 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EEQ41516.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EEQ41516.1 - 0.072 12.8 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Cytidylate kinase RNA_helicase PF00910.22 EEQ41516.1 - 0.078 13.4 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 EEQ41516.1 - 0.092 13.0 0.2 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.15 EEQ41516.1 - 0.13 11.8 1.6 0.23 11.0 1.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_11 PF13086.6 EEQ41516.1 - 0.33 10.7 8.2 0.38 10.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain BAF1_ABF1 PF04684.13 EEQ41516.1 - 1.3 8.0 19.1 0.016 14.3 9.8 1.9 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Menin PF05053.13 EEQ41516.1 - 2.1 6.6 15.0 0.13 10.6 9.3 1.7 2 0 0 2 2 2 0 Menin SARAF PF06682.12 EEQ41516.1 - 7 6.2 8.5 15 5.1 8.5 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Apc15p PF05841.11 EEQ41516.1 - 8.7 7.2 11.0 0.76 10.6 1.4 3.1 3 0 0 3 3 3 0 Apc15p protein Lon_C PF05362.13 EEQ41517.1 - 3.1e-56 190.2 0.0 3.5e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain ChlI PF13541.6 EEQ41517.1 - 0.00017 21.4 0.0 0.00022 21.1 0.0 1.2 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase zf-UBR PF02207.20 EEQ41518.1 - 9.8e-12 44.9 11.5 9.8e-12 44.9 11.5 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ING PF12998.7 EEQ41518.1 - 0.29 11.7 4.1 2.8 8.6 2.1 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-C2HE PF16278.5 EEQ41518.1 - 4.2 7.9 7.4 0.6 10.6 1.8 2.7 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger MCM PF00493.23 EEQ41519.1 - 3e-100 333.9 0.0 4.4e-100 333.4 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM2_N PF12619.8 EEQ41519.1 - 6.5e-44 149.9 31.3 6.5e-44 149.9 31.3 2.6 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_OB PF17207.3 EEQ41519.1 - 1.6e-37 128.2 0.0 3.1e-37 127.2 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EEQ41519.1 - 1.4e-26 92.7 0.2 2.9e-26 91.7 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EEQ41519.1 - 7.9e-11 42.5 0.7 2.6e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 EEQ41519.1 - 7.7e-08 32.0 0.0 5.7e-06 25.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EEQ41519.1 - 2.5e-07 30.8 0.0 1.6e-06 28.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EEQ41519.1 - 0.00029 20.7 0.0 0.0027 17.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EEQ41519.1 - 0.0049 16.6 0.1 0.042 13.5 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain RST PF12174.8 EEQ41519.1 - 0.084 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain MFS_1 PF07690.16 EEQ41521.1 - 1.6e-27 96.4 19.5 2.4e-27 95.8 19.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Metallophos PF00149.28 EEQ41523.1 - 0.0032 18.0 0.0 0.0052 17.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase KRE1 PF17056.5 EEQ41524.1 - 5e-27 93.4 6.7 9.2e-27 92.6 6.7 1.4 1 0 0 1 1 1 1 Killer toxin-resistance protein 1 DUF3446 PF11928.8 EEQ41524.1 - 0.8 10.1 15.0 0.15 12.4 11.4 1.7 1 1 1 2 2 2 0 Early growth response N-terminal domain DUF202 PF02656.15 EEQ41525.1 - 1.4e-20 73.5 0.6 1.4e-20 73.5 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TauE PF01925.19 EEQ41525.1 - 0.018 14.7 4.0 0.02 14.6 4.0 1.0 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE TMEM141 PF15110.6 EEQ41525.1 - 0.018 15.6 0.3 0.027 15.0 0.3 1.3 1 0 0 1 1 1 0 TMEM141 protein family DUF373 PF04123.13 EEQ41525.1 - 0.026 14.0 2.1 0.028 13.9 2.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF5336 PF17270.2 EEQ41525.1 - 0.23 11.1 2.6 0.34 10.5 0.1 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5336) Methyltransf_16 PF10294.9 EEQ41526.1 - 1.9e-15 57.0 0.0 5.1e-14 52.4 0.0 2.0 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EEQ41526.1 - 0.0003 20.7 0.0 0.00043 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EEQ41526.1 - 0.0032 18.1 0.1 0.0082 16.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EEQ41526.1 - 0.022 14.6 0.5 0.061 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ41526.1 - 0.13 13.1 0.1 0.24 12.2 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Antimicrobial_1 PF08018.11 EEQ41526.1 - 0.24 11.6 0.9 0.54 10.5 0.9 1.5 1 0 0 1 1 1 0 Frog antimicrobial peptide Glyco_hydro_125 PF06824.11 EEQ41528.1 - 9.1e-168 558.4 0.0 1.1e-167 558.1 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) NCE101 PF11654.8 EEQ41528.1 - 0.11 12.3 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 ATP_bind_1 PF03029.17 EEQ41529.1 - 6.5e-81 271.7 0.2 6.5e-81 271.7 0.2 1.5 2 0 0 2 2 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EEQ41529.1 - 2e-07 30.7 4.5 1.5e-06 27.9 0.4 3.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EEQ41529.1 - 1.9e-06 27.7 0.0 5.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EEQ41529.1 - 2.7e-05 24.2 0.0 0.29 11.0 0.0 3.4 3 0 0 3 3 3 2 RsgA GTPase MeaB PF03308.16 EEQ41529.1 - 3.3e-05 23.0 0.1 0.077 12.0 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EEQ41529.1 - 8.4e-05 22.8 0.1 0.00026 21.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EEQ41529.1 - 0.00016 21.8 0.1 0.0035 17.4 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EEQ41529.1 - 0.00027 20.7 0.1 0.037 13.8 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 EEQ41529.1 - 0.00054 19.5 0.0 0.59 9.6 0.0 3.3 2 1 0 2 2 2 1 ADP-ribosylation factor family NACHT PF05729.12 EEQ41529.1 - 0.0015 18.5 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EEQ41529.1 - 0.0016 18.7 0.0 0.0059 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EEQ41529.1 - 0.0028 17.1 3.9 0.48 9.8 0.0 3.1 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EEQ41529.1 - 0.0033 17.0 0.1 0.07 12.7 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_18 PF13238.6 EEQ41529.1 - 0.0047 17.5 1.6 0.022 15.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 EEQ41529.1 - 0.0055 16.3 0.4 0.081 12.5 0.4 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EEQ41529.1 - 0.0055 16.3 0.0 0.066 12.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EEQ41529.1 - 0.0079 15.7 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region Roc PF08477.13 EEQ41529.1 - 0.0083 16.3 0.1 1.1 9.5 0.0 2.9 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EEQ41529.1 - 0.0087 16.5 0.1 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EEQ41529.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 EEQ41529.1 - 0.021 14.6 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 EEQ41529.1 - 0.024 13.8 0.0 0.066 12.4 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.18 EEQ41529.1 - 0.028 14.2 0.0 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 EEQ41529.1 - 0.042 13.9 1.9 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Pox_A32 PF04665.12 EEQ41529.1 - 0.079 12.4 0.4 1.1 8.7 0.0 2.3 3 0 0 3 3 2 0 Poxvirus A32 protein LpxK PF02606.14 EEQ41529.1 - 0.089 11.9 0.0 0.19 10.8 0.0 1.5 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase APS_kinase PF01583.20 EEQ41529.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 Adenylylsulphate kinase G-alpha PF00503.20 EEQ41529.1 - 0.21 10.7 6.1 0.24 10.5 0.0 3.1 3 1 1 4 4 4 0 G-protein alpha subunit CobT PF06213.12 EEQ41529.1 - 5.2 6.4 15.4 8.4 5.7 15.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT EMC3_TMCO1 PF01956.16 EEQ41530.1 - 2.9e-46 157.3 0.1 3.7e-46 157.0 0.1 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF3767 PF12597.8 EEQ41531.1 - 5.1e-38 129.0 0.1 6.8e-38 128.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) CPP1-like PF11833.8 EEQ41531.1 - 0.25 11.0 1.4 0.3 10.7 0.6 1.7 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like AAA PF00004.29 EEQ41532.1 - 1.3e-56 190.7 0.1 1.9e-42 144.8 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EEQ41532.1 - 4.7e-20 71.8 1.5 9.4e-20 70.8 0.3 2.2 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 EEQ41532.1 - 4e-11 43.6 3.5 0.00012 22.5 0.2 4.4 2 2 0 3 3 3 2 AAA ATPase domain ABC_tran PF00005.27 EEQ41532.1 - 9.6e-08 32.6 0.9 0.00037 21.0 0.0 3.4 3 0 0 3 3 3 2 ABC transporter AAA_lid_3 PF17862.1 EEQ41532.1 - 7e-07 29.0 0.0 4.1e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 EEQ41532.1 - 4.6e-06 26.9 4.0 0.12 12.6 0.1 4.5 2 2 1 3 3 3 2 AAA domain NB-ARC PF00931.22 EEQ41532.1 - 1.2e-05 24.7 0.1 0.0044 16.2 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 EEQ41532.1 - 1.4e-05 25.1 0.0 0.034 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EEQ41532.1 - 1.9e-05 24.3 2.8 1.2 8.6 0.1 4.0 2 2 1 4 4 4 2 AAA domain AAA_18 PF13238.6 EEQ41532.1 - 2.8e-05 24.7 0.0 0.21 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EEQ41532.1 - 3.3e-05 23.9 4.9 0.025 14.5 1.1 4.0 3 1 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 EEQ41532.1 - 6.7e-05 23.1 0.0 0.029 14.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EEQ41532.1 - 0.00012 22.2 0.0 0.64 10.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 EEQ41532.1 - 0.00019 21.2 0.1 0.36 10.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EEQ41532.1 - 0.00032 20.5 0.0 0.31 10.8 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EEQ41532.1 - 0.00044 20.6 0.0 1.7 9.1 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 EEQ41532.1 - 0.00056 19.9 0.0 1.2 9.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EEQ41532.1 - 0.0012 18.6 0.1 0.38 10.4 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.18 EEQ41532.1 - 0.0012 18.8 0.0 0.047 13.5 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein RuvB_N PF05496.12 EEQ41532.1 - 0.0017 18.1 0.0 0.054 13.2 0.0 3.0 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EEQ41532.1 - 0.0023 17.3 0.0 1.7 7.9 0.0 2.7 2 0 0 2 2 2 1 KaiC ATPase_2 PF01637.18 EEQ41532.1 - 0.0025 17.7 6.5 0.0051 16.8 0.0 3.5 3 1 0 4 4 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EEQ41532.1 - 0.003 16.8 0.0 0.094 11.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TIP49 PF06068.13 EEQ41532.1 - 0.0047 16.2 0.1 0.17 11.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EEQ41532.1 - 0.0061 16.0 0.1 0.56 9.5 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EEQ41532.1 - 0.0065 16.5 0.0 3.4 7.7 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EEQ41532.1 - 0.01 15.6 0.1 0.19 11.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.15 EEQ41532.1 - 0.012 15.6 0.0 0.084 12.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4667 PF15700.5 EEQ41532.1 - 0.013 15.6 0.7 0.013 15.6 0.7 2.7 4 0 0 4 4 3 0 Domain of unknown function (DUF4667) AAA_24 PF13479.6 EEQ41532.1 - 0.016 15.0 0.3 6.3 6.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EEQ41532.1 - 0.017 14.4 0.7 2.5 7.3 0.0 2.7 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) MRF_C1 PF13887.6 EEQ41532.1 - 0.017 14.2 0.0 0.037 13.2 0.0 1.5 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 AAA_28 PF13521.6 EEQ41532.1 - 0.024 14.9 0.0 9.2 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EEQ41532.1 - 0.024 13.7 0.0 0.14 11.2 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 EEQ41532.1 - 0.054 12.8 0.0 7.1 5.9 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.6 EEQ41532.1 - 0.069 13.5 0.1 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EEQ41532.1 - 0.095 12.1 0.0 2.1 7.7 0.0 2.9 4 0 0 4 4 4 0 Bacterial TniB protein MMM1 PF10296.9 EEQ41533.1 - 1.1e-08 34.5 0.2 0.00011 21.4 0.0 2.3 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 SF3a60_bindingd PF12108.8 EEQ41533.1 - 0.067 13.1 0.2 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF4611 PF15387.6 EEQ41533.1 - 0.39 10.9 4.7 1.1 9.5 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) GFO_IDH_MocA PF01408.22 EEQ41534.1 - 2.8e-21 76.5 0.0 4.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EEQ41534.1 - 9.4e-12 45.0 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 EEQ41534.1 - 0.0064 16.9 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.19 EEQ41534.1 - 0.13 13.0 0.0 0.28 11.9 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Sld5 PF05916.11 EEQ41535.1 - 3.7e-16 59.6 0.5 5.4e-16 59.0 0.5 1.3 1 0 0 1 1 1 1 GINS complex protein GCIP PF13324.6 EEQ41535.1 - 0.013 15.1 1.3 0.017 14.7 1.3 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting T6PP_N PF18572.1 EEQ41535.1 - 0.04 13.8 1.1 0.08 12.8 1.1 1.5 1 0 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain A_thal_3526 PF09713.10 EEQ41535.1 - 0.12 12.7 1.4 1.9 8.8 0.0 2.6 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) Med11 PF10280.9 EEQ41536.1 - 2.4e-18 66.9 3.6 2.8e-18 66.7 3.6 1.0 1 0 0 1 1 1 1 Mediator complex protein ING PF12998.7 EEQ41536.1 - 0.0027 18.2 1.9 0.0041 17.7 0.7 1.8 1 1 1 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding DUF641 PF04859.12 EEQ41536.1 - 0.0055 17.0 0.5 0.0078 16.6 0.5 1.4 1 1 0 1 1 1 1 Plant protein of unknown function (DUF641) eIF-6 PF01912.18 EEQ41536.1 - 0.025 14.0 0.1 0.36 10.2 0.0 2.1 2 0 0 2 2 2 0 eIF-6 family Enkurin PF13864.6 EEQ41536.1 - 0.13 12.7 3.5 0.81 10.2 2.7 2.3 1 1 1 2 2 2 0 Calmodulin-binding DUF5595 PF18077.1 EEQ41536.1 - 3 8.0 7.6 5.7 7.1 0.2 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF5595) Mur_ligase_M PF08245.12 EEQ41537.1 - 0.017 15.1 2.3 0.63 10.0 0.1 3.2 2 2 0 2 2 2 0 Mur ligase middle domain PC_rep PF01851.22 EEQ41537.1 - 0.044 14.2 0.0 2.6 8.7 0.0 3.4 3 0 0 3 3 3 0 Proteasome/cyclosome repeat RIG-I_C PF18119.1 EEQ41537.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain WD40 PF00400.32 EEQ41538.1 - 7.4e-12 45.6 6.3 0.14 13.1 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_3 PF13570.6 EEQ41538.1 - 0.18 12.3 0.1 7.1 7.3 0.0 3.2 4 0 0 4 4 4 0 PQQ-like domain WD40 PF00400.32 EEQ41539.1 - 4e-46 154.0 17.8 1.9e-08 34.8 1.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ41539.1 - 3.3e-10 40.1 1.0 0.019 15.2 0.0 4.9 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EEQ41539.1 - 0.00041 19.4 1.2 0.38 9.6 0.0 4.1 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EEQ41539.1 - 0.00074 18.3 8.9 0.17 10.5 0.0 4.4 1 1 1 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.12 EEQ41539.1 - 0.0044 16.9 1.8 2.2 8.3 0.0 4.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat UPF0052 PF01933.18 EEQ41540.1 - 1.5e-56 191.8 0.0 2e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 IF-2B PF01008.17 EEQ41541.1 - 6.5e-68 229.0 0.0 7.6e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family UCH PF00443.29 EEQ41542.1 - 5.1e-64 216.2 4.0 1e-63 215.2 1.2 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EEQ41542.1 - 1.6e-19 70.7 4.2 9.7e-19 68.1 1.1 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 EEQ41542.1 - 0.0074 16.8 0.1 0.025 15.1 0.1 2.0 1 1 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 EEQ41542.1 - 0.028 14.2 0.6 0.076 12.8 0.6 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Y_phosphatase2 PF03162.13 EEQ41543.1 - 4.6e-43 146.6 0.0 5.5e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Aminotran_1_2 PF00155.21 EEQ41544.1 - 6.3e-62 209.8 0.0 7.6e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EEQ41544.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.20 EEQ41544.1 - 0.013 14.2 0.1 0.023 13.4 0.1 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DegT_DnrJ_EryC1 PF01041.17 EEQ41544.1 - 0.025 13.9 0.0 0.14 11.5 0.0 2.1 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EEQ41544.1 - 0.091 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF1658 PF07871.11 EEQ41544.1 - 0.13 12.2 1.1 0.32 11.0 1.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1658) ABC_tran PF00005.27 EEQ41545.1 - 9e-25 87.8 0.0 1e-11 45.5 0.0 2.9 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EEQ41545.1 - 1.2e-05 25.3 0.8 0.06 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EEQ41545.1 - 0.0024 18.0 0.1 0.17 12.2 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EEQ41545.1 - 0.0095 16.2 0.7 4.2 7.6 0.5 3.1 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EEQ41545.1 - 0.013 15.5 0.0 0.089 12.7 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 EEQ41545.1 - 0.025 13.7 0.5 4.2 6.5 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 EEQ41545.1 - 0.047 14.1 0.0 0.1 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EEQ41545.1 - 0.05 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EEQ41545.1 - 0.12 12.4 0.1 0.65 10.1 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EEQ41545.1 - 0.8 10.2 4.7 0.31 11.5 0.8 2.2 3 0 0 3 3 3 0 AAA domain BSD PF03909.17 EEQ41546.1 - 1.5e-14 53.7 2.1 3.3e-14 52.6 0.5 2.3 2 0 0 2 2 2 1 BSD domain Baculo_PEP_C PF04513.12 EEQ41546.1 - 0.00074 19.6 3.6 0.15 12.1 0.8 3.0 2 1 1 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Histidinol_dh PF00815.20 EEQ41546.1 - 0.13 11.3 2.4 0.16 10.9 2.0 1.5 1 1 0 1 1 1 0 Histidinol dehydrogenase Perilipin PF03036.16 EEQ41546.1 - 0.15 11.0 4.0 0.22 10.5 0.0 2.5 1 1 1 2 2 2 0 Perilipin family DUF1664 PF07889.12 EEQ41546.1 - 0.27 11.3 4.8 3.3 7.8 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AI-2E_transport PF01594.16 EEQ41546.1 - 0.6 9.2 1.3 0.91 8.6 0.5 1.7 2 0 0 2 2 2 0 AI-2E family transporter NPV_P10 PF05531.12 EEQ41546.1 - 0.63 10.5 4.1 8.2 7.0 0.3 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 EEQ41546.1 - 0.97 8.9 10.4 4.2 6.8 10.4 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF883 PF05957.13 EEQ41546.1 - 1.5 9.5 5.7 16 6.2 0.4 3.3 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) EntA_Immun PF08951.10 EEQ41546.1 - 1.8 9.0 8.4 0.48 10.8 0.6 3.2 4 0 0 4 4 4 0 Enterocin A Immunity DUF4407 PF14362.6 EEQ41546.1 - 2.2 7.6 8.3 0.32 10.3 3.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Response_reg PF00072.24 EEQ41547.1 - 9.6e-19 67.6 0.0 5.2e-13 49.1 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Asp_protease PF09668.10 EEQ41548.1 - 2.4e-35 121.0 0.0 3.9e-35 120.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EEQ41548.1 - 1.6e-16 60.6 0.0 3.4e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EEQ41548.1 - 5.2e-10 39.8 0.1 1.5e-09 38.4 0.1 1.8 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 EEQ41548.1 - 1.9e-09 37.2 0.1 4.4e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.23 EEQ41548.1 - 3.3e-07 30.0 0.2 6.5e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP PF00077.20 EEQ41548.1 - 3.6e-06 27.2 0.0 7.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 EEQ41548.1 - 3.8e-06 26.6 0.2 7.8e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.6 EEQ41548.1 - 0.012 15.5 0.3 0.023 14.5 0.3 1.6 1 0 0 1 1 1 0 UBA-like domain Ubiquitin_4 PF18036.1 EEQ41548.1 - 0.059 13.4 0.1 3.6 7.7 0.1 2.5 1 1 0 1 1 1 0 Ubiquitin-like domain RuvA_C PF07499.13 EEQ41548.1 - 0.062 13.8 0.0 0.25 11.8 0.1 1.9 2 0 0 2 2 2 0 RuvA, C-terminal domain UN_NPL4 PF11543.8 EEQ41548.1 - 0.08 13.4 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 CUE PF02845.16 EEQ41548.1 - 0.085 12.6 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 CUE domain GDI PF00996.18 EEQ41549.1 - 1.7e-217 722.2 0.1 1.9e-217 722.0 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 EEQ41549.1 - 0.076 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Dda helicase SH3 domain Peptidase_M24 PF00557.24 EEQ41550.1 - 8.1e-58 195.5 0.0 1.2e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EEQ41550.1 - 6.9e-22 77.5 0.1 1.6e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain T4BSS_DotI_IcmL PF11393.8 EEQ41550.1 - 0.02 14.4 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component KN_motif PF12075.8 EEQ41550.1 - 0.024 14.4 0.2 0.063 13.1 0.2 1.7 1 0 0 1 1 1 0 KN motif DUF3793 PF12672.7 EEQ41550.1 - 0.1 12.6 0.3 0.26 11.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) JAB PF01398.21 EEQ41551.1 - 1.7e-31 108.7 0.1 3.3e-31 107.7 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EEQ41551.1 - 6.1e-13 49.2 1.9 1.3e-12 48.1 1.9 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EEQ41551.1 - 1.1e-07 31.6 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SAM35 PF10806.8 EEQ41552.1 - 8.5e-32 110.1 0.4 2.8e-31 108.4 0.1 2.0 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex IQCJ-SCHIP1 PF15157.6 EEQ41552.1 - 0.094 12.5 0.3 0.29 11.0 0.3 1.8 1 1 1 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Acetyltransf_10 PF13673.7 EEQ41553.1 - 1.3e-20 73.7 0.0 1.7e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ41553.1 - 4e-14 52.8 0.0 8.1e-14 51.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EEQ41553.1 - 2.6e-07 30.9 0.0 4e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EEQ41553.1 - 0.021 14.3 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 EEQ41553.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 EEQ41553.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom22 PF04281.13 EEQ41553.1 - 0.27 11.0 1.6 0.44 10.3 1.6 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 CAF1C_H4-bd PF12265.8 EEQ41554.1 - 1.6e-22 79.5 0.1 5.7e-22 77.8 0.1 2.0 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EEQ41554.1 - 2.6e-14 53.4 12.8 1.5e-06 28.8 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat BING4CT PF08149.11 EEQ41554.1 - 0.0056 16.5 0.0 16 5.4 0.0 3.6 4 0 0 4 4 4 2 BING4CT (NUC141) domain Sulfate_transp PF00916.20 EEQ41555.1 - 1e-61 208.8 10.4 1.4e-61 208.4 10.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EEQ41555.1 - 1.8e-18 66.3 0.0 3.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EEQ41555.1 - 0.0012 19.2 3.6 0.0012 19.2 3.6 2.8 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 EEQ41555.1 - 0.092 13.1 0.0 0.27 11.6 0.0 1.8 1 1 0 1 1 1 0 STAS domain ETF PF01012.21 EEQ41556.1 - 1.7e-41 142.1 9.4 2.8e-41 141.4 9.4 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EEQ41556.1 - 2.5e-35 120.3 1.1 2.3e-34 117.2 0.3 2.3 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain PGM_PMM_II PF02879.16 EEQ41556.1 - 0.11 13.2 0.0 0.3 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Fungal_trans PF04082.18 EEQ41558.1 - 1.8e-12 46.9 0.1 3.1e-12 46.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ41558.1 - 8.3e-07 29.0 9.1 1.3e-06 28.4 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipoprotein_20 PF13942.6 EEQ41558.1 - 0.012 15.5 0.5 0.024 14.6 0.5 1.3 1 0 0 1 1 1 0 YfhG lipoprotein Holin_9 PF16936.5 EEQ41559.1 - 0.051 13.7 2.7 0.11 12.7 2.7 1.5 1 0 0 1 1 1 0 Putative holin CAP PF00188.26 EEQ41560.1 - 5.4e-17 62.8 3.5 5.4e-17 62.8 3.5 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family AAA_12 PF13087.6 EEQ41562.1 - 8.4e-54 182.2 0.0 1.6e-53 181.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EEQ41562.1 - 6.3e-52 176.9 0.7 2.2e-51 175.2 0.7 2.1 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EEQ41562.1 - 8.4e-10 38.7 0.0 3.6e-07 30.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EEQ41562.1 - 9.8e-09 35.7 0.0 3.4e-07 30.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EEQ41562.1 - 1.6e-07 31.3 0.9 0.59 9.8 0.0 3.8 3 1 0 4 4 4 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 EEQ41562.1 - 6.3e-06 26.3 1.2 1.1e-05 25.6 0.2 1.9 2 0 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EEQ41562.1 - 1.8e-05 25.3 4.6 3.9e-05 24.3 4.6 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EEQ41562.1 - 4.8e-05 23.7 0.6 0.00027 21.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EEQ41562.1 - 0.00053 19.3 0.5 0.0012 18.2 0.5 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 EEQ41562.1 - 0.0013 18.7 0.5 0.0031 17.4 0.3 1.8 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.21 EEQ41562.1 - 0.0024 17.4 0.5 0.0048 16.5 0.5 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 EEQ41562.1 - 0.0056 16.9 0.5 0.017 15.3 0.5 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EEQ41562.1 - 0.006 17.0 0.0 0.018 15.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EEQ41562.1 - 0.0077 15.7 0.0 0.28 10.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 EEQ41562.1 - 0.0096 16.3 0.4 0.033 14.6 0.3 2.1 2 1 0 2 2 1 1 AAA ATPase domain ATPase_2 PF01637.18 EEQ41562.1 - 0.02 14.8 2.9 0.031 14.2 0.4 2.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EEQ41562.1 - 0.02 14.6 0.0 0.73 9.5 0.0 2.9 3 1 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EEQ41562.1 - 0.035 14.1 0.1 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) UvrD_C_2 PF13538.6 EEQ41562.1 - 0.037 13.9 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Coilin_N PF15862.5 EEQ41562.1 - 0.11 12.2 4.3 0.27 11.1 2.3 2.1 2 0 0 2 2 2 0 Coilin N-terminus Hydin_ADK PF17213.3 EEQ41562.1 - 2.2 8.5 6.4 77 3.5 6.4 2.4 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain SpoVAD PF07451.11 EEQ41564.1 - 0.0058 15.4 0.1 0.0074 15.0 0.1 1.1 1 0 0 1 1 1 1 Stage V sporulation protein AD (SpoVAD) Npa1 PF11707.8 EEQ41565.1 - 5.6e-72 242.9 5.5 5.6e-72 242.9 5.5 2.1 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EEQ41565.1 - 5.4e-44 150.2 0.5 5.4e-44 150.2 0.5 2.3 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 TIP39 PF14980.6 EEQ41565.1 - 0.025 14.5 0.1 0.082 12.8 0.1 1.9 1 0 0 1 1 1 0 TIP39 peptide Pkinase PF00069.25 EEQ41566.1 - 2.8e-69 233.4 0.0 4.6e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41566.1 - 6.7e-27 94.4 0.0 1.4e-26 93.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ41566.1 - 5.9e-07 29.1 0.1 0.53 9.6 0.0 3.1 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EEQ41566.1 - 0.0052 15.6 0.0 0.0084 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RXT2_N PF08595.11 EEQ41566.1 - 0.039 14.0 2.8 0.12 12.4 2.8 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_ser-thr_kin PF05445.11 EEQ41566.1 - 0.069 12.1 1.2 0.11 11.5 1.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Astro_capsid_p PF12226.8 EEQ41566.1 - 0.093 11.9 8.4 0.16 11.1 8.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Sigma70_ner PF04546.13 EEQ41566.1 - 0.77 9.6 5.9 1.4 8.8 5.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region GCIP PF13324.6 EEQ41566.1 - 1.4 8.4 13.0 0.42 10.2 8.8 1.9 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting BUD22 PF09073.10 EEQ41566.1 - 1.5 8.1 10.3 2.4 7.4 10.3 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EEQ41566.1 - 1.8 7.8 8.7 3.2 7.0 8.7 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 EEQ41566.1 - 2.1 6.8 7.1 3.5 6.0 7.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 EEQ41566.1 - 2.3 7.6 11.6 3.7 6.9 11.6 1.2 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EEQ41566.1 - 2.3 6.2 16.2 3.2 5.8 16.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi ABC_tran PF00005.27 EEQ41567.1 - 2.5e-49 167.3 0.1 6.5e-25 88.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EEQ41567.1 - 8.7e-37 126.6 41.4 1.7e-20 73.4 19.0 2.3 2 0 0 2 2 2 2 ABC-2 type transporter RsgA_GTPase PF03193.16 EEQ41567.1 - 1.3e-09 38.2 2.0 0.00076 19.4 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EEQ41567.1 - 1.4e-08 34.9 8.6 0.0057 16.5 0.0 4.3 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ41567.1 - 2.2e-07 30.6 0.1 0.0012 18.3 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EEQ41567.1 - 2.5e-07 31.1 0.3 0.016 15.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EEQ41567.1 - 2.8e-07 31.2 0.5 0.012 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEQ41567.1 - 9.2e-07 29.2 0.4 0.1 12.8 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EEQ41567.1 - 3.1e-06 26.8 0.8 0.013 15.2 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EEQ41567.1 - 7.8e-06 26.4 0.2 0.11 12.8 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 EEQ41567.1 - 2.2e-05 24.8 0.1 0.011 16.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase ATPase_2 PF01637.18 EEQ41567.1 - 3.3e-05 23.9 0.0 0.0039 17.1 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EEQ41567.1 - 4e-05 24.2 0.0 0.36 11.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EEQ41567.1 - 5e-05 23.3 0.6 0.024 14.6 0.0 2.8 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EEQ41567.1 - 6.7e-05 22.7 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EEQ41567.1 - 7.4e-05 22.7 0.0 0.6 10.0 0.0 2.8 2 0 0 2 2 2 2 NACHT domain T2SSE PF00437.20 EEQ41567.1 - 9.3e-05 21.6 1.6 0.13 11.3 0.1 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.29 EEQ41567.1 - 0.00025 21.5 0.0 0.33 11.4 0.0 3.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EEQ41567.1 - 0.00034 20.7 1.3 0.18 11.9 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EEQ41567.1 - 0.00039 20.2 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EEQ41567.1 - 0.00048 20.3 0.5 2.4 8.4 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 EEQ41567.1 - 0.0016 18.1 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EEQ41567.1 - 0.0016 18.4 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_19 PF13245.6 EEQ41567.1 - 0.0023 18.3 0.1 0.7 10.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EEQ41567.1 - 0.0023 17.5 1.0 2 8.0 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EEQ41567.1 - 0.0027 17.8 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EEQ41567.1 - 0.0052 16.8 0.0 3.7 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EEQ41567.1 - 0.0072 15.8 0.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Septin PF00735.18 EEQ41567.1 - 0.011 15.0 0.3 1.2 8.3 0.1 2.2 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 EEQ41567.1 - 0.013 14.9 0.4 0.86 8.9 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family dNK PF01712.19 EEQ41567.1 - 0.014 15.3 0.5 2.9 7.7 0.1 2.6 3 0 0 3 3 2 0 Deoxynucleoside kinase SRP54 PF00448.22 EEQ41567.1 - 0.019 14.6 0.4 6.9 6.2 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.17 EEQ41567.1 - 0.041 13.7 0.9 6.9 6.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Cytidylate_kin PF02224.18 EEQ41567.1 - 0.046 13.5 0.2 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_17 PF13207.6 EEQ41567.1 - 0.046 14.2 0.1 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EEQ41567.1 - 0.046 13.6 0.2 3.9 7.4 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 EEQ41567.1 - 0.059 13.4 0.4 7.2 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) SRPRB PF09439.10 EEQ41567.1 - 0.063 12.7 0.1 7.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 EEQ41567.1 - 0.065 12.4 0.0 5 6.2 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain PRK PF00485.18 EEQ41567.1 - 0.076 12.7 0.8 4.7 6.9 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 EEQ41567.1 - 0.097 12.9 0.2 9.8 6.4 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EEQ41567.1 - 0.12 11.9 1.6 8.3 5.9 0.1 2.7 3 0 0 3 3 3 0 P-loop containing dynein motor region RuvB_N PF05496.12 EEQ41567.1 - 0.13 12.0 0.1 15 5.3 0.0 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_13 PF13166.6 EEQ41567.1 - 0.15 10.7 1.4 8.4 4.9 0.3 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EEQ41567.1 - 0.18 11.1 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 EEQ41567.1 - 0.22 11.3 0.1 2.1 8.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EEQ41567.1 - 0.26 10.7 0.6 3.1 7.2 0.0 2.7 4 0 0 4 4 2 0 ADP-ribosylation factor family zf-C2H2 PF00096.26 EEQ41570.1 - 1.4e-06 28.4 15.3 5.8e-05 23.3 4.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EEQ41570.1 - 5.3e-05 23.4 13.5 0.00018 21.8 2.3 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EEQ41570.1 - 0.002 18.8 12.1 0.12 13.3 2.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EEQ41570.1 - 0.007 16.7 6.2 0.74 10.3 0.9 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EEQ41570.1 - 0.018 15.1 8.1 0.21 11.6 3.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EEQ41570.1 - 0.018 14.8 4.1 0.035 13.9 1.8 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type PknG_rubred PF16919.5 EEQ41570.1 - 0.66 10.1 7.0 0.085 13.0 1.6 1.9 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain FYVE PF01363.21 EEQ41570.1 - 0.75 10.0 9.1 6.4 7.0 9.1 2.1 1 1 0 1 1 1 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 EEQ41570.1 - 1.7 9.0 5.3 2.5 8.5 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding MIP PF00230.20 EEQ41572.1 - 2.4e-05 24.2 3.6 3e-05 23.9 3.0 1.4 1 1 0 1 1 1 1 Major intrinsic protein PALP PF00291.25 EEQ41573.1 - 2.8e-72 243.6 0.3 3.2e-72 243.4 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AA_permease PF00324.21 EEQ41574.1 - 1.7e-16 59.9 13.4 2e-16 59.7 13.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ41574.1 - 0.025 13.4 12.4 0.03 13.2 12.4 1.0 1 0 0 1 1 1 0 Amino acid permease DUF5637 PF18687.1 EEQ41574.1 - 0.16 12.0 9.0 13 5.9 7.4 3.0 2 1 0 2 2 2 0 Family of unknown function (DUF5637) AA_permease PF00324.21 EEQ41575.1 - 4.3e-09 35.5 0.0 5.6e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ41576.1 - 5.3e-36 124.2 18.3 6.3e-36 124.0 18.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EEQ41576.1 - 2.1e-10 40.0 19.5 2.9e-10 39.6 19.5 1.2 1 0 0 1 1 1 1 Amino acid permease Xpo1 PF08389.12 EEQ41577.1 - 1.1e-28 100.2 0.1 1.1e-28 100.2 0.1 3.7 4 0 0 4 4 4 1 Exportin 1-like protein RuvB_N PF05496.12 EEQ41577.1 - 0.083 12.6 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mur_ligase_C PF02875.21 EEQ41577.1 - 0.094 13.0 0.0 13 6.2 0.0 2.6 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain ANAPC4_WD40 PF12894.7 EEQ41578.1 - 2.6e-10 40.4 0.0 0.067 13.5 0.0 5.8 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EEQ41578.1 - 4.1e-08 33.7 1.1 0.29 12.1 0.0 5.7 4 2 1 6 6 6 2 WD domain, G-beta repeat SURF2 PF05477.11 EEQ41578.1 - 2.7 7.6 6.1 4.9 6.8 6.1 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) KCH PF16944.5 EEQ41580.1 - 2.3e-74 250.4 22.6 2.8e-74 250.1 22.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3453 PF11935.8 EEQ41581.1 - 5.4e-47 160.3 1.1 1.3e-46 159.0 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DSPc PF00782.20 EEQ41582.1 - 3.7e-27 94.8 0.7 7.5e-20 71.1 0.1 3.6 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EEQ41582.1 - 2e-05 24.3 0.0 9.7e-05 22.0 0.0 2.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase DUF2457 PF10446.9 EEQ41582.1 - 0.09 11.9 18.3 0.21 10.7 18.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EEQ41582.1 - 0.42 8.8 14.7 0.89 7.8 14.7 1.4 1 0 0 1 1 1 0 CDC45-like protein Asp PF00026.23 EEQ41583.1 - 5.5e-49 167.3 2.4 6.9e-49 167.0 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EEQ41583.1 - 1.2e-11 45.2 1.2 6.2e-06 26.6 0.3 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EEQ41583.1 - 0.013 16.1 0.2 8.6 7.1 0.1 3.2 2 1 0 2 2 2 0 Aspartyl protease FUSC PF04632.12 EEQ41586.1 - 0.096 11.2 9.8 0.13 10.7 9.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA PF00004.29 EEQ41587.1 - 3.6e-16 59.8 0.0 1.1e-15 58.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EEQ41587.1 - 4.4e-16 59.1 0.2 9.4e-16 58.0 0.2 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EEQ41587.1 - 9.2e-14 51.5 0.0 6.4e-12 45.5 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EEQ41587.1 - 2.7e-08 34.0 0.0 6.3e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EEQ41587.1 - 1.3e-06 28.7 0.0 3.1e-05 24.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EEQ41587.1 - 1.1e-05 25.4 0.0 4.7e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EEQ41587.1 - 1.3e-05 25.6 0.2 0.00052 20.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EEQ41587.1 - 1.6e-05 24.7 0.0 6.2e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EEQ41587.1 - 0.00012 21.5 0.0 0.0037 16.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EEQ41587.1 - 0.00095 19.2 0.0 0.0026 17.8 0.0 1.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EEQ41587.1 - 0.0013 18.8 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EEQ41587.1 - 0.0013 18.4 0.0 0.0036 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_assoc_2 PF16193.5 EEQ41587.1 - 0.0016 18.7 0.1 0.004 17.5 0.1 1.8 1 1 0 1 1 1 1 AAA C-terminal domain DUF815 PF05673.13 EEQ41587.1 - 0.0018 17.5 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EEQ41587.1 - 0.0019 18.2 0.1 0.012 15.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EEQ41587.1 - 0.0046 16.7 0.0 0.033 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EEQ41587.1 - 0.0089 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 EEQ41587.1 - 0.016 14.5 0.0 0.046 13.0 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EEQ41587.1 - 0.018 15.4 0.0 0.14 12.5 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EEQ41587.1 - 0.028 14.3 0.0 0.18 11.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EEQ41587.1 - 0.03 14.6 0.0 0.08 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain DNA_pol3_gamma3 PF12169.8 EEQ41587.1 - 0.041 13.8 0.1 0.16 11.8 0.1 1.9 1 1 1 2 2 2 0 DNA polymerase III subunits gamma and tau domain III RNA_helicase PF00910.22 EEQ41587.1 - 0.051 14.0 0.0 0.18 12.2 0.0 2.0 2 0 0 2 2 2 0 RNA helicase PhoH PF02562.16 EEQ41587.1 - 0.075 12.5 0.0 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 EEQ41587.1 - 0.084 13.4 0.0 0.25 11.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain BTB_2 PF02214.22 EEQ41589.1 - 0.074 13.4 0.0 0.19 12.1 0.0 1.7 2 0 0 2 2 2 0 BTB/POZ domain RecG_N PF17190.4 EEQ41590.1 - 0.016 15.9 1.7 0.43 11.3 0.3 2.9 2 1 0 2 2 2 0 RecG N-terminal helical domain ZapB PF06005.12 EEQ41590.1 - 0.016 15.6 3.4 0.49 10.9 0.8 2.6 2 1 0 2 2 2 0 Cell division protein ZapB DUF922 PF06037.11 EEQ41590.1 - 0.046 13.5 0.5 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF922) DUF1543 PF07566.12 EEQ41590.1 - 0.067 12.9 0.2 0.98 9.2 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1543) 7TMR-HDED PF07697.11 EEQ41590.1 - 0.15 12.2 1.5 0.12 12.5 0.3 1.5 2 0 0 2 2 2 0 7TM-HD extracellular PX PF00787.24 EEQ41591.1 - 4.3e-09 36.3 0.0 9.4e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 PX domain PAP2 PF01569.21 EEQ41592.1 - 1.6e-25 89.5 2.0 3.1e-25 88.5 2.0 1.5 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 EEQ41592.1 - 0.0023 17.7 4.8 0.018 14.7 4.4 2.4 1 1 0 1 1 1 1 PAP2 superfamily SLATT_1 PF18181.1 EEQ41592.1 - 0.49 10.3 1.8 1.2 9.0 0.2 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Choline_kinase PF01633.20 EEQ41593.1 - 1.1e-44 152.6 0.0 2.3e-43 148.3 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EEQ41593.1 - 0.0003 20.8 0.0 0.0014 18.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1639 PF07797.14 EEQ41593.1 - 0.26 11.3 0.9 0.62 10.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) HGTP_anticodon2 PF12745.7 EEQ41594.1 - 5.9e-80 268.6 6.4 5.9e-80 268.6 6.4 2.5 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EEQ41594.1 - 8.7e-61 205.6 0.0 1.1e-36 126.6 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41594.1 - 2.9e-32 112.0 0.0 4.3e-20 72.1 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EEQ41594.1 - 1.2e-18 67.5 0.0 3.7e-18 65.9 0.0 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 EEQ41594.1 - 4.1e-10 39.4 0.5 1.1e-09 38.1 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 EEQ41594.1 - 5e-05 22.8 0.0 0.0043 16.4 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Mre11_DNA_bind PF04152.14 EEQ41595.1 - 2.3e-43 148.4 3.1 2.3e-43 148.4 3.1 1.9 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EEQ41595.1 - 1e-12 49.0 0.1 2.3e-12 47.9 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sec16 PF12932.7 EEQ41595.1 - 0.39 11.3 2.0 0.55 10.8 0.0 2.2 3 1 0 3 3 3 0 Vesicle coat trafficking protein Sec16 mid-region DUF507 PF04368.13 EEQ41595.1 - 0.54 10.2 4.3 0.22 11.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF507) ATP11 PF06644.11 EEQ41596.1 - 5.5e-90 301.9 5.7 6.2e-90 301.7 5.7 1.0 1 0 0 1 1 1 1 ATP11 protein Pol_alpha_B_N PF08418.10 EEQ41596.1 - 0.014 15.4 2.1 0.02 14.9 2.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal IPPT PF01715.17 EEQ41596.1 - 0.018 14.9 0.0 0.028 14.2 0.0 1.3 1 1 0 1 1 1 0 IPP transferase DUF1479 PF07350.12 EEQ41596.1 - 0.042 12.6 1.6 0.06 12.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) Ph1570 PF09638.10 EEQ41596.1 - 0.1 12.5 1.3 0.21 11.5 1.3 1.6 1 0 0 1 1 1 0 Ph1570 protein Mt_ATP-synt_B PF05405.14 EEQ41596.1 - 0.14 11.8 2.6 0.26 10.9 2.6 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DAGK_acc PF00609.19 EEQ41596.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase accessory domain zf-DNL PF05180.12 EEQ41597.1 - 2.2e-29 101.2 0.4 3.1e-29 100.7 0.4 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 EEQ41597.1 - 0.052 13.5 0.6 4.2 7.4 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 EEQ41597.1 - 0.056 13.5 0.1 0.079 13.0 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CSL PF05207.13 EEQ41597.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 CSL zinc finger Anti-TRAP PF15777.5 EEQ41597.1 - 0.12 12.3 0.1 0.29 11.1 0.1 1.6 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn-ribbon_8 PF09723.10 EEQ41597.1 - 0.13 12.4 0.5 0.27 11.4 0.5 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-C3HC4_3 PF13920.6 EEQ41598.1 - 0.00019 21.2 12.9 0.00019 21.2 12.9 4.5 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 EEQ41598.1 - 0.14 12.7 0.2 0.14 12.7 0.2 6.5 6 1 1 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EEQ41598.1 - 0.14 13.0 0.3 0.14 13.0 0.3 6.9 7 3 1 8 8 8 0 C2H2-type zinc finger FlhC PF05280.11 EEQ41598.1 - 7.1 6.3 12.7 0.94 9.2 0.9 2.5 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) PGP_phosphatase PF09419.10 EEQ41599.1 - 6.7e-71 237.3 0.0 8.1e-71 237.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EEQ41599.1 - 4.9e-06 26.5 0.0 9.7e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EEQ41599.1 - 0.0028 18.0 0.0 0.0041 17.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FeoA PF04023.14 EEQ41599.1 - 0.015 15.5 0.0 0.067 13.4 0.0 2.2 1 1 0 1 1 1 0 FeoA domain Glycos_transf_2 PF00535.26 EEQ41599.1 - 0.052 13.3 0.0 0.099 12.4 0.0 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 2 HAD_2 PF13419.6 EEQ41599.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase FAT PF02259.23 EEQ41600.1 - 3.7e-78 263.2 5.3 8.4e-78 262.0 5.3 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EEQ41600.1 - 1.3e-37 130.0 0.0 3.3e-37 128.7 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EEQ41600.1 - 4.7e-06 26.3 0.1 1.5e-05 24.7 0.1 1.9 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.8 EEQ41600.1 - 0.003 17.5 0.5 0.048 13.6 0.1 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) CLASP_N PF12348.8 EEQ41600.1 - 0.27 10.8 2.4 1.2 8.6 0.7 2.9 2 1 1 3 3 3 0 CLASP N terminal CTD_bind PF04818.13 EEQ41600.1 - 0.35 11.7 1.7 53 4.8 0.0 4.6 4 0 0 4 4 4 0 RNA polymerase II-binding domain. Sec7_N PF12783.7 EEQ41601.1 - 0.0054 16.7 11.0 1.3 8.9 0.0 5.2 5 1 1 6 6 6 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Dopey_N PF04118.14 EEQ41601.1 - 0.052 12.7 1.9 0.18 10.9 0.2 2.4 2 1 0 2 2 2 0 Dopey, N-terminal DUF2013 PF09431.10 EEQ41601.1 - 0.054 13.7 0.5 1.1 9.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2013) Tim29 PF10171.9 EEQ41601.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 Fig1 PF12351.8 EEQ41602.1 - 1.4e-43 149.0 7.7 1.4e-43 149.0 7.7 1.5 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Acyltransferase PF01553.21 EEQ41603.1 - 2.8e-20 72.3 0.0 4.3e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EEQ41603.1 - 4.2e-07 30.0 0.1 3.6e-06 27.0 0.1 2.2 1 1 0 1 1 1 1 Acyltransferase C-terminus MFS_1 PF07690.16 EEQ41605.1 - 4.8e-47 160.6 8.3 9.6e-47 159.6 8.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ41605.1 - 2.4e-13 49.8 0.0 2.4e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.15 EEQ41605.1 - 5.1e-06 25.7 1.7 2.7e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 PUCC protein OATP PF03137.20 EEQ41605.1 - 1e-05 24.1 0.5 0.00013 20.4 0.1 2.5 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EEQ41605.1 - 0.00026 20.0 0.0 0.002 17.0 0.0 2.2 1 1 1 2 2 2 1 MFS_1 like family V_ATPase_I PF01496.19 EEQ41605.1 - 0.0069 14.4 0.5 0.0097 13.9 0.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family CDC45 PF02724.14 EEQ41605.1 - 0.042 12.1 3.5 0.058 11.7 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Ctr PF04145.15 EEQ41605.1 - 0.061 13.9 0.1 0.18 12.4 0.1 1.8 1 0 0 1 1 1 0 Ctr copper transporter family DUF4834 PF16118.5 EEQ41605.1 - 0.092 13.7 0.3 0.24 12.4 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 EEQ41605.1 - 0.27 11.0 1.3 0.44 10.3 1.3 1.3 1 0 0 1 1 1 0 Connexin TRAP_alpha PF03896.16 EEQ41605.1 - 0.67 9.1 2.1 1.1 8.4 2.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CPSF100_C PF13299.6 EEQ41605.1 - 1.2 9.2 5.2 2 8.6 5.2 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.8 EEQ41605.1 - 1.4 7.6 6.2 2 7.2 6.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM76 PF16046.5 EEQ41605.1 - 1.4 8.2 6.5 2 7.7 6.5 1.1 1 0 0 1 1 1 0 FAM76 protein DUF4637 PF15470.6 EEQ41605.1 - 1.5 8.5 9.3 2.4 7.8 9.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Trypan_PARP PF05887.11 EEQ41605.1 - 1.6 8.7 6.1 3.5 7.6 6.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DNA_pol_phi PF04931.13 EEQ41605.1 - 2 6.4 5.2 2.9 5.9 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 EEQ41605.1 - 3 8.3 6.4 5.8 7.3 6.4 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 EEQ41605.1 - 3.4 6.3 7.9 6.5 5.4 7.9 1.4 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 EEQ41605.1 - 8 6.5 6.9 12 5.8 6.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 NPR3 PF03666.13 EEQ41605.1 - 10 4.8 8.5 15 4.2 8.5 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Exo84_C PF16528.5 EEQ41608.1 - 9.2e-14 51.7 0.1 3.4e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Exocyst component 84 C-terminal COG2 PF06148.11 EEQ41608.1 - 9.3e-05 22.5 0.2 0.00031 20.8 0.1 1.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EEQ41608.1 - 0.00082 19.4 0.2 0.002 18.1 0.2 1.7 1 0 0 1 1 1 1 Vps51/Vps67 SKA2 PF16740.5 EEQ41608.1 - 0.083 12.7 0.1 0.23 11.2 0.1 1.7 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 WD40 PF00400.32 EEQ41609.1 - 1.3e-11 44.8 16.0 0.0015 19.3 0.9 6.9 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ41609.1 - 7.2e-08 32.6 0.1 0.69 10.2 0.0 6.2 2 2 5 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EEQ41609.1 - 2.3e-06 27.3 1.2 5e-06 26.3 0.1 2.2 2 0 0 2 2 2 1 LisH FemAB PF02388.16 EEQ41609.1 - 0.022 13.7 0.6 0.031 13.1 0.6 1.1 1 0 0 1 1 1 0 FemAB family Hira PF07569.11 EEQ41609.1 - 0.37 10.5 11.0 1.1 8.9 0.7 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split SIP1 PF04938.12 EEQ41610.1 - 1.2e-09 38.2 1.6 1.3e-08 34.9 1.6 2.2 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) CDC45 PF02724.14 EEQ41610.1 - 0.00052 18.4 11.4 0.00062 18.2 11.4 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EEQ41610.1 - 0.012 13.8 23.9 0.021 13.1 23.9 1.3 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 EEQ41610.1 - 0.014 14.2 7.6 0.026 13.3 7.6 1.4 1 0 0 1 1 1 0 Raftlin DUF4045 PF13254.6 EEQ41610.1 - 0.026 14.2 9.5 0.04 13.6 9.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) SAPS PF04499.15 EEQ41610.1 - 0.16 10.8 9.2 0.21 10.3 9.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Presenilin PF01080.17 EEQ41610.1 - 0.43 9.3 12.6 0.67 8.6 12.6 1.3 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.9 EEQ41610.1 - 0.66 8.8 9.1 1 8.1 9.1 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 EEQ41610.1 - 1.4 8.1 8.1 2.7 7.1 8.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter CCSAP PF15748.5 EEQ41610.1 - 5 7.2 14.6 10 6.2 14.6 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF913 PF06025.12 EEQ41610.1 - 6.5 5.6 11.2 12 4.8 11.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Paf1 PF03985.13 EEQ41610.1 - 8.5 5.3 24.2 18 4.1 24.2 1.6 1 0 0 1 1 1 0 Paf1 LAP1C PF05609.12 EEQ41610.1 - 9.5 5.2 17.6 17 4.4 17.6 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Tfb4 PF03850.14 EEQ41611.1 - 5.6e-90 301.6 0.2 6.4e-90 301.4 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Rad50_zn_hook PF04423.14 EEQ41611.1 - 0.0057 16.5 0.3 0.012 15.5 0.0 1.7 2 0 0 2 2 2 1 Rad50 zinc hook motif ADH_zinc_N PF00107.26 EEQ41611.1 - 0.02 14.9 0.9 0.04 13.9 0.5 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase DUF4776 PF16003.5 EEQ41611.1 - 0.059 12.4 2.2 0.083 11.9 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) MafB19-deam PF14437.6 EEQ41612.1 - 1.1e-13 51.1 0.1 1.4e-13 50.8 0.1 1.0 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EEQ41612.1 - 1e-12 47.8 0.1 1.4e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 EEQ41612.1 - 0.0029 17.7 0.2 0.0078 16.3 0.0 1.8 2 1 1 3 3 3 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 EEQ41612.1 - 0.0034 17.3 1.6 0.12 12.3 0.3 2.0 1 1 1 2 2 2 1 APOBEC-like N-terminal domain APOBEC2 PF18772.1 EEQ41612.1 - 0.0052 16.9 0.6 0.059 13.4 0.6 2.0 1 1 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EEQ41612.1 - 0.006 16.7 1.6 0.15 12.2 0.3 2.1 1 1 1 2 2 2 1 Novel AID APOBEC clade 1 NAD2 PF18782.1 EEQ41612.1 - 0.039 14.0 0.1 0.21 11.7 0.1 1.9 1 1 0 1 1 1 0 Novel AID APOBEC clade 2 APOBEC3 PF18771.1 EEQ41612.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 APOBEC3 Bd3614-deam PF14439.6 EEQ41612.1 - 0.075 13.1 1.3 0.11 12.5 1.3 1.4 1 1 0 1 1 1 0 Bd3614-like deaminase APOBEC4 PF18775.1 EEQ41612.1 - 0.23 11.7 1.9 9.8 6.4 0.6 2.1 1 1 1 2 2 2 0 APOBEC4 Pkinase PF00069.25 EEQ41613.1 - 6.4e-19 68.3 0.0 1.2e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EEQ41613.1 - 6.7e-06 26.7 0.5 0.044 14.7 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EEQ41613.1 - 4.8e-05 22.8 0.0 8.5e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EEQ41613.1 - 0.00088 19.3 0.1 0.0016 18.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family HEAT PF02985.22 EEQ41613.1 - 0.0013 18.8 0.0 1.5 9.3 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat Thioredoxin_2 PF13098.6 EEQ41613.1 - 0.063 13.7 0.0 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Mg_trans_NIPA PF05653.14 EEQ41614.1 - 1.1e-110 369.4 17.6 1.3e-110 369.2 17.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EEQ41614.1 - 2.8e-05 24.3 6.9 2.8e-05 24.3 6.9 3.4 2 2 0 3 3 3 1 EamA-like transporter family Saf_2TM PF18303.1 EEQ41614.1 - 0.79 9.3 3.1 2.1 7.9 0.1 2.9 1 1 0 2 2 2 0 SAVED-fused 2TM effector domain Methyltransf_28 PF02636.17 EEQ41618.1 - 3.4e-38 131.8 0.0 1.1e-36 126.8 0.0 2.3 2 1 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 EEQ41618.1 - 0.12 13.1 0.1 2.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Pcc1 PF09341.10 EEQ41619.1 - 1.1e-17 64.0 0.0 1.2e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 PriA_CRR PF18319.1 EEQ41619.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 PriA DNA helicase Cys-rich region (CRR) domain DNA_pol_A PF00476.20 EEQ41620.1 - 5e-55 187.1 0.1 9.4e-55 186.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase family A DNApol_Exo PF18136.1 EEQ41620.1 - 4.7e-12 45.6 0.3 1e-11 44.5 0.3 1.6 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain RNA_pol_3_Rpc31 PF11705.8 EEQ41621.1 - 0.11 12.8 17.0 0.19 11.9 17.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 GldM_N PF12081.8 EEQ41621.1 - 0.22 11.6 4.3 0.38 10.8 4.3 1.2 1 0 0 1 1 1 0 GldM N-terminal domain DNA_pol_phi PF04931.13 EEQ41621.1 - 0.47 8.5 15.4 0.63 8.1 15.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 EEQ41621.1 - 1.7 7.8 7.3 2.7 7.1 7.3 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sds3 PF08598.11 EEQ41622.1 - 0.14 12.1 4.9 1.3 9.0 4.9 2.4 1 1 0 1 1 1 0 Sds3-like PWWP PF00855.17 EEQ41623.1 - 1.7e-18 66.8 0.2 4.5e-18 65.4 0.2 1.9 1 1 0 1 1 1 1 PWWP domain Med26 PF08711.11 EEQ41623.1 - 2.8e-07 30.4 1.1 4.2e-07 29.9 0.1 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Macoilin PF09726.9 EEQ41623.1 - 0.053 12.1 15.3 0.068 11.7 15.3 1.1 1 0 0 1 1 1 0 Macoilin family Lin-8 PF03353.15 EEQ41623.1 - 0.059 12.9 10.1 0.092 12.3 10.1 1.5 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 EEQ41623.1 - 0.78 8.0 17.5 1.3 7.2 17.5 1.4 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 EEQ41623.1 - 2.4 6.6 26.3 3.8 6.0 26.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.7 EEQ41623.1 - 7.8 4.5 13.9 11 4.0 13.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein eIF-5a PF01287.20 EEQ41624.1 - 2.8e-30 104.2 0.7 4e-30 103.7 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EEQ41624.1 - 0.0048 16.9 0.0 0.0082 16.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain zf-RING_2 PF13639.6 EEQ41626.1 - 5.5e-11 42.6 4.9 9.2e-11 41.9 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EEQ41626.1 - 1.4e-07 31.1 1.4 1.4e-07 31.1 1.4 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EEQ41626.1 - 1.6e-06 27.9 4.9 2.7e-06 27.1 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EEQ41626.1 - 2.2e-06 27.5 3.4 3.9e-06 26.7 3.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEQ41626.1 - 2.9e-06 27.2 4.3 2.2e-05 24.4 0.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EEQ41626.1 - 7.8e-06 25.7 2.5 1.4e-05 24.9 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ41626.1 - 5.9e-05 23.3 9.2 0.00025 21.3 9.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EEQ41626.1 - 0.00017 21.6 2.8 0.00031 20.7 2.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EEQ41626.1 - 0.0052 16.4 5.1 0.0093 15.6 5.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EEQ41626.1 - 0.007 16.4 0.5 0.007 16.4 0.5 2.5 1 1 1 2 2 2 1 KIAA1045 RING finger zf-C3HC4_3 PF13920.6 EEQ41626.1 - 0.01 15.7 3.2 0.017 15.0 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EEQ41626.1 - 0.018 14.9 4.7 0.036 13.9 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 EEQ41626.1 - 0.095 12.6 4.1 0.2 11.6 4.1 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EEQ41626.1 - 0.68 9.9 8.4 0.08 12.9 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 RRM_1 PF00076.22 EEQ41627.1 - 3.5e-10 39.5 0.0 6.6e-10 38.7 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tr-sialidase_C PF11052.8 EEQ41627.1 - 0.081 13.1 6.6 23 5.2 0.2 3.6 3 0 0 3 3 3 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal WSC PF01822.19 EEQ41628.1 - 1.2e-10 41.4 15.2 1.2e-10 41.4 15.2 2.1 2 1 0 2 2 2 1 WSC domain SKG6 PF08693.10 EEQ41628.1 - 6.2e-06 25.5 1.1 6.2e-06 25.5 1.1 2.2 2 0 0 2 2 2 1 Transmembrane alpha-helix domain SOG2 PF10428.9 EEQ41628.1 - 0.59 9.3 12.7 0.72 9.0 12.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 EEQ41628.1 - 3.5 6.4 7.7 4.9 5.9 7.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SPX PF03105.19 EEQ41628.1 - 4.2 7.2 9.6 5.7 6.8 9.6 1.2 1 0 0 1 1 1 0 SPX domain DUF2408 PF10303.9 EEQ41629.1 - 1.9e-48 164.4 15.2 8e-34 117.1 0.1 5.2 2 2 2 4 4 4 3 Protein of unknown function (DUF2408) DUF241 PF03087.14 EEQ41629.1 - 0.0039 17.0 1.9 0.014 15.2 0.1 2.6 2 1 0 2 2 2 1 Arabidopsis protein of unknown function DUF4200 PF13863.6 EEQ41629.1 - 0.016 15.6 1.2 0.016 15.6 1.2 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4200) FUSC PF04632.12 EEQ41629.1 - 0.017 13.7 5.1 0.066 11.7 1.1 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family AF-4 PF05110.13 EEQ41629.1 - 0.17 9.9 1.9 0.26 9.3 1.9 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GoLoco PF02188.17 EEQ41629.1 - 0.29 10.7 2.2 0.8 9.3 0.1 2.8 2 0 0 2 2 2 0 GoLoco motif Cut8 PF08559.10 EEQ41630.1 - 7.1e-65 219.0 0.1 9.1e-65 218.6 0.1 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein XPC-binding PF09280.11 EEQ41630.1 - 0.0008 19.1 0.4 0.002 17.8 0.4 1.6 1 0 0 1 1 1 1 XPC-binding domain BING4CT PF08149.11 EEQ41631.1 - 3.4e-38 129.3 0.0 5.3e-34 115.9 0.0 3.3 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 EEQ41631.1 - 1.2e-08 35.5 1.3 0.00018 22.2 0.0 5.2 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EEQ41631.1 - 1.1e-05 25.6 0.0 1.4 9.3 0.0 4.4 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EEQ41631.1 - 0.013 15.1 0.0 0.041 13.5 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain DHO_dh PF01180.21 EEQ41632.1 - 1.1e-97 326.8 0.0 1.3e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EEQ41632.1 - 0.12 11.3 0.3 1.7 7.6 0.3 2.4 2 1 0 2 2 2 0 FMN-dependent dehydrogenase DASH_Dam1 PF08653.10 EEQ41633.1 - 5e-21 74.3 1.1 2.4e-20 72.1 0.1 2.1 2 0 0 2 2 2 1 DASH complex subunit Dam1 DUF3338 PF11819.8 EEQ41633.1 - 0.00034 20.6 0.6 0.00063 19.7 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3338) bZIP_1 PF00170.21 EEQ41633.1 - 0.005 16.9 4.2 0.012 15.7 1.2 2.5 2 0 0 2 2 2 1 bZIP transcription factor Phage_GP20 PF06810.11 EEQ41633.1 - 0.057 13.2 1.9 2.3 8.0 0.3 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 ORF6C PF10552.9 EEQ41633.1 - 0.18 11.9 2.2 1.2 9.3 1.1 2.1 2 0 0 2 2 2 0 ORF6C domain FlaC_arch PF05377.11 EEQ41633.1 - 0.18 12.2 1.0 22 5.5 0.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 EEQ41633.1 - 0.47 10.8 4.8 0.34 11.2 1.3 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Tropomyosin_1 PF12718.7 EEQ41633.1 - 0.54 10.4 5.3 9.3 6.4 1.7 2.2 2 0 0 2 2 2 0 Tropomyosin like bZIP_2 PF07716.15 EEQ41633.1 - 2 8.6 5.6 0.69 10.0 1.6 2.2 2 1 0 2 2 2 0 Basic region leucine zipper GET2 PF08690.10 EEQ41634.1 - 3.1e-87 293.1 0.1 3.6e-87 292.9 0.1 1.0 1 0 0 1 1 1 1 GET complex subunit GET2 N36 PF11438.8 EEQ41634.1 - 0.14 12.0 1.5 2.2 8.2 0.1 2.3 2 0 0 2 2 2 0 36-mer N-terminal peptide of the N protein (N36) SURF1 PF02104.15 EEQ41635.1 - 2.3e-41 142.0 0.0 5e-41 140.9 0.0 1.5 1 1 0 1 1 1 1 SURF1 family Nop PF01798.18 EEQ41636.1 - 4.5e-86 288.0 0.1 4.5e-86 288.0 0.1 1.9 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EEQ41636.1 - 2.8e-20 72.5 0.4 2.8e-20 72.5 0.4 2.9 2 1 0 2 2 2 1 NOP5NT (NUC127) domain PPP4R2 PF09184.11 EEQ41636.1 - 0.52 9.9 23.0 0.73 9.4 23.0 1.2 1 0 0 1 1 1 0 PPP4R2 RR_TM4-6 PF06459.12 EEQ41636.1 - 0.86 9.4 27.2 1.4 8.7 27.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EEQ41636.1 - 6 7.0 9.4 13 5.8 9.4 1.6 1 0 0 1 1 1 0 DDHD domain RP-C_C PF11800.8 EEQ41636.1 - 7.1 6.7 15.2 40 4.2 0.0 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region GAGA_bind PF06217.12 EEQ41636.1 - 8.9 6.5 19.2 17 5.6 19.2 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Catalase PF00199.19 EEQ41637.1 - 1.6e-191 636.5 0.2 2.1e-191 636.0 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EEQ41637.1 - 4.8e-12 45.9 1.2 2.6e-11 43.6 0.1 2.7 4 0 0 4 4 4 1 Catalase-related immune-responsive DUF5071 PF16804.5 EEQ41637.1 - 0.12 12.7 0.1 5.5 7.3 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5071) Fungal_trans_2 PF11951.8 EEQ41640.1 - 6.4e-81 272.1 0.0 9.4e-81 271.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EEQ41640.1 - 1.4e-07 31.5 9.8 2.6e-07 30.6 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UQ_con PF00179.26 EEQ41641.1 - 8.2e-50 168.1 0.0 9.5e-50 167.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EEQ41641.1 - 0.0027 18.0 0.0 0.0034 17.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EEQ41641.1 - 0.004 16.9 0.0 0.0053 16.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B Bromodomain PF00439.25 EEQ41642.1 - 2.7e-16 59.4 0.1 8.5e-16 57.8 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EEQ41642.1 - 8e-09 35.4 0.1 2.1e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 EEQ41642.1 - 0.03 14.5 0.0 0.1 12.7 0.0 1.9 1 0 0 1 1 1 0 Histone-fold protein RCC1 PF00415.18 EEQ41643.1 - 1.1e-14 54.8 5.1 7.2e-05 23.3 0.2 5.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EEQ41643.1 - 5.8e-10 38.7 0.9 7.6e-05 22.4 0.1 3.0 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EEQ41643.1 - 9.3e-05 22.6 1.2 0.59 10.4 0.1 3.7 2 1 1 3 3 3 2 BTB/POZ domain Ank_2 PF12796.7 EEQ41643.1 - 0.00015 22.3 0.7 0.0012 19.4 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EEQ41643.1 - 0.015 15.7 0.8 0.06 13.9 0.1 2.5 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 EEQ41643.1 - 0.016 15.5 0.2 0.085 13.2 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EEQ41643.1 - 0.018 15.6 0.9 0.29 11.8 0.0 2.7 1 1 2 3 3 3 0 Ankyrin repeats (many copies) aGPT-Pplase3 PF18746.1 EEQ41643.1 - 0.083 12.2 0.0 0.2 10.9 0.0 1.6 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 Kelch_5 PF13854.6 EEQ41643.1 - 1.8 8.6 4.6 1.7 8.7 0.0 3.3 3 0 0 3 3 3 0 Kelch motif DNA_binding_1 PF01035.20 EEQ41644.1 - 2e-21 75.9 0.0 2.4e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain US30 PF17624.2 EEQ41645.1 - 2.6 7.0 4.0 4.3 6.3 4.0 1.3 1 0 0 1 1 1 0 Family of unknown function C_tripleX PF02363.19 EEQ41646.1 - 3.8 8.0 14.5 1.3e+02 3.2 14.5 2.6 1 1 0 1 1 1 0 Cysteine rich repeat Gly-zipper_OmpA PF13436.6 EEQ41647.1 - 0.055 13.3 13.0 0.13 12.1 13.0 1.5 1 0 0 1 1 1 0 Glycine-zipper domain ubiquitin PF00240.23 EEQ41647.1 - 0.08 12.7 0.0 11 5.9 0.0 2.9 2 0 0 2 2 2 0 Ubiquitin family Zip PF02535.22 EEQ41647.1 - 1.7 7.8 5.5 1.8 7.7 3.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter Macoilin PF09726.9 EEQ41647.1 - 8.4 4.8 12.1 0.27 9.7 5.4 1.7 2 0 0 2 2 2 0 Macoilin family PGM_PMM_I PF02878.16 EEQ41648.1 - 0.06 13.1 0.2 0.25 11.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I zf-Mss51 PF13824.6 EEQ41649.1 - 2.1e-18 66.2 0.9 4.6e-18 65.1 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 EEQ41649.1 - 0.089 12.6 0.2 0.21 11.4 0.2 1.7 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain PRKCSH PF07915.13 EEQ41652.1 - 1.2e-10 42.2 0.0 2.8e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EEQ41652.1 - 0.073 12.8 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Glucosidase II beta subunit-like protein DUF382 PF04037.13 EEQ41653.1 - 3.1e-52 176.1 0.2 3.1e-52 176.1 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EEQ41653.1 - 4.9e-16 58.3 0.0 8.3e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 PSP Zn_clus PF00172.18 EEQ41654.1 - 4.7e-05 23.4 7.9 0.00013 22.0 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Molybdopterin PF00384.22 EEQ41656.1 - 2.7e-67 227.6 0.1 6.3e-65 219.8 0.1 2.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EEQ41656.1 - 1.7e-20 72.9 1.0 5.2e-20 71.3 1.0 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EEQ41656.1 - 3.9e-17 62.7 0.1 1.8e-16 60.6 0.0 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EEQ41656.1 - 4.8e-15 54.8 0.6 4.8e-15 54.8 0.6 2.5 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EEQ41656.1 - 4.3e-09 36.2 0.3 4.3e-09 36.2 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 EEQ41656.1 - 0.0022 17.8 0.4 0.18 11.5 0.0 2.7 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Lyx_isomer PF07385.12 EEQ41656.1 - 0.035 13.4 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 D-lyxose isomerase Fer4 PF00037.27 EEQ41656.1 - 0.099 12.5 1.1 3.5 7.6 0.3 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain TNT PF14021.6 EEQ41656.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin Fer4_19 PF06902.11 EEQ41656.1 - 1.4 9.1 4.8 5.7 7.1 2.1 3.0 2 1 0 2 2 2 0 Divergent 4Fe-4S mono-cluster Fer4_4 PF12800.7 EEQ41656.1 - 6.2 7.6 6.5 1.5 9.5 1.6 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain DUF2034 PF10356.9 EEQ41657.1 - 1.3e-45 155.1 0.0 4e-45 153.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EEQ41657.1 - 2e-07 31.0 0.0 4.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease Glyco_hydro_18 PF00704.28 EEQ41658.1 - 1.6e-23 83.9 1.6 5.9e-23 82.1 1.6 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 NAD_binding_5 PF07994.12 EEQ41659.1 - 1.7e-144 481.1 0.1 2e-144 480.9 0.1 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EEQ41659.1 - 1.2e-45 154.2 0.3 2.7e-45 153.1 0.3 1.7 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase AMP-binding PF00501.28 EEQ41660.1 - 1.2e-87 294.3 0.0 1.6e-87 293.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EEQ41660.1 - 0.05 14.6 0.0 0.14 13.2 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Asparaginase PF00710.20 EEQ41661.1 - 3e-55 186.7 0.0 4.8e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EEQ41661.1 - 4.2e-19 68.8 0.1 3.1e-18 66.1 0.1 2.1 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain COX6B PF02297.17 EEQ41662.1 - 1.3e-22 79.8 7.3 1.5e-22 79.6 7.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EEQ41662.1 - 0.13 12.6 2.0 0.9 9.9 1.9 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 TRAPPC9-Trs120 PF08626.11 EEQ41663.1 - 0 1106.1 0.4 0 1106.0 0.4 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 EEQ41663.1 - 0.011 16.0 0.6 0.011 16.0 0.6 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Proteasome PF00227.26 EEQ41664.1 - 6.6e-47 159.5 0.1 1e-46 158.8 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EEQ41664.1 - 4.5e-12 45.1 0.2 4.5e-12 45.1 0.2 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal Aha1_N PF09229.11 EEQ41665.1 - 2.7e-34 118.3 0.0 2.7e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EEQ41665.1 - 1.3e-18 67.5 0.1 1.3e-18 67.5 0.1 1.6 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.13 EEQ41665.1 - 0.0036 17.4 0.5 0.0063 16.6 0.5 1.3 1 0 0 1 1 1 1 Poxvirus A12 protein ROS_MUCR PF05443.11 EEQ41665.1 - 0.3 11.1 2.8 0.3 11.1 1.3 1.6 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein ADH_zinc_N PF00107.26 EEQ41666.1 - 5.4e-21 74.9 0.4 1.1e-20 73.9 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EEQ41666.1 - 1.6e-07 31.1 0.1 3.8e-07 29.8 0.1 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 EEQ41666.1 - 0.00021 20.7 0.4 0.00033 20.0 0.4 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 EEQ41666.1 - 0.00021 22.3 0.0 0.00041 21.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EEQ41666.1 - 0.0012 19.1 0.1 0.002 18.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EEQ41666.1 - 0.0047 17.2 0.2 0.016 15.5 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain Pep_deformylase PF01327.21 EEQ41666.1 - 0.0049 16.5 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 Polypeptide deformylase UDPG_MGDP_dh_N PF03721.14 EEQ41666.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EEQ41666.1 - 0.074 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HycI PF01750.18 EEQ41666.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease Iso_dh PF00180.20 EEQ41667.1 - 4.7e-100 335.1 0.1 6e-100 334.8 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Formyl_trans_N PF00551.19 EEQ41668.1 - 2.4e-43 148.0 1.2 3.1e-42 144.4 1.2 1.9 1 1 0 1 1 1 1 Formyl transferase GTP_EFTU PF00009.27 EEQ41669.1 - 7e-69 231.3 0.2 9.7e-69 230.8 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EEQ41669.1 - 2e-33 114.7 0.0 9.5e-33 112.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EEQ41669.1 - 4.4e-21 74.7 0.0 1e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EEQ41669.1 - 7.7e-13 48.6 0.4 2.1e-12 47.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EEQ41669.1 - 9.4e-13 48.1 0.0 4.4e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EEQ41669.1 - 4.5e-05 23.5 0.2 9.6e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase LRV_FeS PF05484.11 EEQ41670.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster Cu_amine_oxid PF01179.20 EEQ41671.1 - 4.6e-145 483.6 0.0 5.5e-145 483.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EEQ41671.1 - 3.1e-24 85.3 0.0 6.7e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EEQ41671.1 - 2.3e-16 59.8 0.0 4.6e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain RNA_Me_trans PF04252.13 EEQ41673.1 - 1.2e-76 256.8 0.0 1.4e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase WWE PF02825.20 EEQ41674.1 - 9.4e-06 26.1 0.1 3.1e-05 24.5 0.1 2.0 1 0 0 1 1 1 1 WWE domain RAP1 PF07218.11 EEQ41674.1 - 0.15 10.4 1.9 0.29 9.4 1.9 1.4 1 1 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF1689 PF07954.11 EEQ41675.1 - 1.8e-38 132.2 1.1 2.5e-38 131.8 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) tRNA-synt_2b PF00587.25 EEQ41676.1 - 4.4e-35 121.3 0.0 9.5e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EEQ41676.1 - 1.3e-16 60.5 2.7 2e-16 59.9 1.3 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA_SAD PF07973.14 EEQ41676.1 - 1e-12 47.9 0.0 2.4e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EEQ41676.1 - 6.8e-12 45.3 0.0 1.9e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 TGS domain Ribosomal_L14 PF00238.19 EEQ41677.1 - 9.1e-48 161.4 1.0 1e-47 161.2 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e UPF0029 PF01205.19 EEQ41678.1 - 2.4e-27 95.3 0.0 2.9e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 FAD-oxidase_C PF02913.19 EEQ41679.1 - 1.4e-56 192.0 0.0 1.8e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EEQ41679.1 - 8.2e-34 116.3 0.1 1.4e-33 115.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Flavin_Reduct PF01613.18 EEQ41680.1 - 3.1e-20 72.8 0.0 4.2e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DHquinase_II PF01220.19 EEQ41681.1 - 7.5e-58 194.1 0.4 8.4e-58 193.9 0.4 1.0 1 0 0 1 1 1 1 Dehydroquinase class II PAC2 PF09754.9 EEQ41682.1 - 7.4e-23 81.7 0.0 1e-22 81.2 0.0 1.1 1 0 0 1 1 1 1 PAC2 family AFT PF08731.11 EEQ41683.1 - 2.2e-18 66.7 6.2 1.7e-09 38.1 0.2 2.8 2 1 1 3 3 3 2 Transcription factor AFT DBD_Tnp_Mut PF03108.15 EEQ41683.1 - 7e-05 22.7 0.2 0.00013 21.8 0.2 1.4 1 0 0 1 1 1 1 MuDR family transposase Ribosomal_L12 PF00542.19 EEQ41686.1 - 3.6e-22 78.5 7.2 3.6e-22 78.5 7.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EEQ41686.1 - 2.3e-16 59.2 2.3 6.3e-16 57.8 0.3 2.4 2 0 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain TFIIS_C PF01096.18 EEQ41687.1 - 1e-14 54.1 12.6 1.5e-14 53.5 3.4 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EEQ41687.1 - 2.6e-12 46.4 4.8 2.6e-12 46.4 4.8 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.7 EEQ41687.1 - 0.00013 21.9 7.3 0.034 14.2 0.6 2.3 2 0 0 2 2 2 2 Double zinc ribbon Nudix_N_2 PF14803.6 EEQ41687.1 - 0.053 13.5 7.0 1.4 8.9 0.8 3.2 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_10 PF10058.9 EEQ41687.1 - 0.066 13.0 12.0 0.58 9.9 3.2 2.6 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-ribbon_3 PF13248.6 EEQ41687.1 - 0.1 12.0 0.3 0.1 12.0 0.3 3.3 4 0 0 4 4 4 0 zinc-ribbon domain DUF3268 PF11672.8 EEQ41687.1 - 0.13 12.6 6.7 0.66 10.3 1.2 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain Zn_ribbon_recom PF13408.6 EEQ41687.1 - 0.13 12.8 6.5 0.68 10.5 0.4 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_9 PF14369.6 EEQ41687.1 - 0.16 12.2 12.3 1.5 9.1 0.7 3.1 2 1 1 3 3 3 0 zinc-ribbon Zn_Tnp_IS1595 PF12760.7 EEQ41687.1 - 0.17 11.9 11.5 0.48 10.4 3.9 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.9 EEQ41687.1 - 0.23 11.6 0.1 0.23 11.6 0.1 3.1 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.6 EEQ41687.1 - 0.55 10.0 0.2 0.55 10.0 0.2 3.4 4 0 0 4 4 3 0 zinc-ribbon domain ADK_lid PF05191.14 EEQ41687.1 - 0.99 9.4 7.1 15 5.7 0.0 3.6 4 0 0 4 4 4 0 Adenylate kinase, active site lid Ogr_Delta PF04606.12 EEQ41687.1 - 1.3 9.1 9.9 0.46 10.5 1.0 2.7 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.10 EEQ41687.1 - 1.4 9.1 13.9 2.3 8.4 0.2 3.8 3 1 1 4 4 4 0 Zinc ribbon domain Lar_restr_allev PF14354.6 EEQ41687.1 - 1.6 9.2 11.2 0.11 12.9 2.1 2.6 2 1 0 2 2 2 0 Restriction alleviation protein Lar C1_4 PF07975.12 EEQ41687.1 - 1.8 8.9 14.3 1.4 9.2 0.3 3.4 2 2 1 3 3 3 0 TFIIH C1-like domain zf-GRF PF06839.12 EEQ41687.1 - 2 8.6 8.6 1.4 9.1 0.1 3.1 3 0 0 3 3 3 0 GRF zinc finger zf-ACC PF17848.1 EEQ41687.1 - 2.1 8.5 18.5 4.2 7.5 3.1 4.2 4 1 0 4 4 4 0 Acetyl-coA carboxylase zinc finger domain DUF2387 PF09526.10 EEQ41687.1 - 2.6 8.3 7.4 5.2 7.3 0.3 2.3 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf_UBZ PF18439.1 EEQ41687.1 - 5.4 6.7 12.7 9.7 5.9 0.2 3.7 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Pkinase PF00069.25 EEQ41688.1 - 6e-74 248.7 0.0 7.6e-74 248.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41688.1 - 9.4e-40 136.5 0.0 1.3e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ41688.1 - 4.8e-06 26.1 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EEQ41688.1 - 0.028 13.4 0.1 0.045 12.7 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EEQ41688.1 - 0.054 12.8 0.1 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Nramp PF01566.18 EEQ41689.1 - 3.5e-83 279.5 19.6 5e-82 275.7 19.6 2.2 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein DUF1576 PF07613.11 EEQ41689.1 - 0.015 14.9 1.7 0.015 14.9 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) RRF_GI PF12614.8 EEQ41690.1 - 0.073 13.2 1.1 2 8.6 0.1 2.1 2 0 0 2 2 2 0 Ribosome recycling factor DUF1601 PF07671.11 EEQ41690.1 - 0.17 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) zf-C2H2 PF00096.26 EEQ41691.1 - 6.3e-06 26.4 6.3 0.00047 20.5 0.5 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF448 PF04296.13 EEQ41691.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF448) HAD PF12710.7 EEQ41692.1 - 2.7e-25 89.9 0.0 3.5e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EEQ41692.1 - 0.0027 17.2 0.0 0.0048 16.3 0.0 1.4 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 EEQ41692.1 - 0.016 14.7 0.0 0.041 13.4 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Ribosom_S30AE_C PF16321.5 EEQ41692.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Pkinase PF00069.25 EEQ41693.1 - 5.9e-73 245.5 0.0 9.8e-73 244.8 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41693.1 - 5e-36 124.3 0.0 1.2e-35 123.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EEQ41693.1 - 6.7e-05 22.3 0.3 0.68 9.2 0.0 3.2 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EEQ41693.1 - 0.0012 17.7 0.0 0.002 16.9 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase PRP1_N PF06424.12 EEQ41693.1 - 0.09 13.2 1.7 10 6.5 0.0 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal SET PF00856.28 EEQ41693.1 - 0.09 13.2 0.4 0.33 11.3 0.3 1.9 2 1 0 2 2 2 0 SET domain SNF2_N PF00176.23 EEQ41694.1 - 1.2e-35 122.8 0.0 4.2e-35 121.1 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EEQ41694.1 - 1.8e-09 37.7 9.1 4.4e-09 36.5 9.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EEQ41694.1 - 1.3e-08 34.6 7.1 2.7e-08 33.5 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EEQ41694.1 - 2.5e-08 33.6 8.4 5.8e-08 32.4 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ41694.1 - 3.5e-08 33.2 8.8 7.7e-08 32.1 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EEQ41694.1 - 1.9e-07 31.3 5.1 5.6e-07 29.7 5.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EEQ41694.1 - 5.2e-07 29.4 5.6 1.1e-06 28.4 5.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ41694.1 - 7.4e-06 25.8 6.5 1.7e-05 24.6 6.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EEQ41694.1 - 9.6e-05 22.3 5.5 0.00021 21.2 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 EEQ41694.1 - 0.00013 22.3 0.0 0.00058 20.2 0.0 2.2 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-ANAPC11 PF12861.7 EEQ41694.1 - 0.021 14.9 2.8 0.065 13.3 2.8 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EEQ41694.1 - 0.024 14.4 5.7 0.038 13.8 3.9 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TAN PF11640.8 EEQ41694.1 - 0.028 14.5 0.7 1 9.5 0.4 2.9 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair zf-RING_10 PF16685.5 EEQ41694.1 - 0.029 14.5 3.7 0.084 13.0 3.7 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EEQ41694.1 - 0.11 12.7 7.0 0.32 11.2 7.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 EEQ41694.1 - 3.6 7.3 5.6 12 5.7 5.6 1.9 1 1 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 EEQ41694.1 - 3.8 7.2 5.8 8.6 6.1 5.8 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type tRNA_anti-codon PF01336.25 EEQ41695.1 - 3.3e-07 30.2 0.9 5.5e-07 29.5 0.9 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 EEQ41695.1 - 7.8e-05 23.3 0.2 0.00028 21.5 0.0 2.1 2 1 0 2 2 2 1 Replication protein A C terminal RMI2 PF16100.5 EEQ41695.1 - 0.0032 17.3 0.2 0.006 16.4 0.2 1.5 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 Rrf2 PF02082.20 EEQ41695.1 - 0.063 13.6 0.0 0.33 11.3 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator DUF4579 PF15158.6 EEQ41696.1 - 0.052 13.3 1.2 0.12 12.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) MFS_1 PF07690.16 EEQ41697.1 - 8.5e-30 103.9 39.1 8.5e-30 103.9 39.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EEQ41697.1 - 5.1e-13 48.7 11.9 5.1e-13 48.7 11.9 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter SWIB PF02201.18 EEQ41699.1 - 1.1e-11 44.4 0.7 3.8e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 SWIB/MDM2 domain Cyt-b5 PF00173.28 EEQ41700.1 - 5.2e-14 52.1 0.0 9.5e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 EEQ41700.1 - 1.2e-07 31.8 21.6 1.2e-07 31.8 21.6 2.6 3 1 0 3 3 3 1 Fatty acid desaturase CBS PF00571.28 EEQ41701.1 - 2.5e-13 50.3 0.0 7.4e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 CBS domain Hormone_3 PF00159.18 EEQ41701.1 - 0.14 12.3 0.0 18 5.5 0.0 2.9 2 0 0 2 2 2 0 Pancreatic hormone peptide RRM_1 PF00076.22 EEQ41702.1 - 4e-36 122.7 0.0 9.2e-17 60.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EEQ41702.1 - 0.0014 18.2 0.0 0.35 10.5 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EEQ41702.1 - 0.0067 16.5 0.0 0.27 11.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif OB_RNB PF08206.11 EEQ41702.1 - 0.041 13.6 1.7 7.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Ribonuclease B OB domain zf-HIT PF04438.16 EEQ41703.1 - 7.7e-09 35.3 8.1 7.7e-09 35.3 8.1 1.7 2 0 0 2 2 2 1 HIT zinc finger Na_trans_assoc PF06512.13 EEQ41703.1 - 0.00054 20.3 0.0 0.0015 18.8 0.0 1.7 1 1 0 1 1 1 1 Sodium ion transport-associated CDC45 PF02724.14 EEQ41703.1 - 0.012 14.0 6.5 0.016 13.5 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Red1 PF07964.11 EEQ41703.1 - 0.26 9.5 8.9 0.049 11.9 2.3 2.0 2 0 0 2 2 2 0 Rec10 / Red1 RRN3 PF05327.11 EEQ41703.1 - 4.1 5.8 6.7 5.6 5.4 6.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 C1_2 PF03107.16 EEQ41703.1 - 7.6 6.9 9.7 5.8 7.3 7.2 2.1 2 0 0 2 2 2 0 C1 domain MFMR_assoc PF16596.5 EEQ41703.1 - 8.3 6.9 14.6 4 7.9 12.0 1.8 2 0 0 2 2 2 0 Disordered region downstream of MFMR Ribosomal_L9_N PF01281.19 EEQ41704.1 - 2.2e-10 39.9 0.0 4.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Stk19 PF10494.9 EEQ41705.1 - 9.5e-74 248.2 0.0 1.3e-73 247.8 0.0 1.2 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF1682 PF07946.14 EEQ41706.1 - 1.2e-84 284.3 9.9 1.4e-84 284.1 9.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) AIG1 PF04548.16 EEQ41706.1 - 0.007 15.7 0.1 0.015 14.6 0.1 1.7 1 0 0 1 1 1 1 AIG1 family PIEZO PF15917.5 EEQ41706.1 - 1.8 8.0 12.3 2.7 7.4 12.3 1.2 1 0 0 1 1 1 0 Piezo Tho2 PF11262.8 EEQ41706.1 - 3.6 6.7 10.9 6.5 5.9 10.9 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Atrophin-1 PF03154.15 EEQ41706.1 - 9.9 4.3 12.2 11 4.1 12.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family Ank_5 PF13857.6 EEQ41707.1 - 1.6e-15 56.9 0.1 1.6e-13 50.6 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EEQ41707.1 - 1.8e-10 41.3 0.2 5.2e-10 39.8 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EEQ41707.1 - 5.2e-10 39.7 0.0 5.3e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EEQ41707.1 - 1.1e-09 38.3 2.5 4.8e-08 33.1 0.3 2.5 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EEQ41707.1 - 1.2e-08 34.5 0.5 1.7e-07 31.0 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Peptidase_M76 PF09768.9 EEQ41708.1 - 5.5e-71 237.8 0.6 6.6e-71 237.6 0.6 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EEQ41708.1 - 0.0044 16.8 0.5 0.0096 15.8 0.2 1.7 1 1 0 1 1 1 1 SprT-like family BSP PF04450.12 EEQ41708.1 - 0.046 13.5 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Peptidase of plants and bacteria Peptidase_M91 PF14891.6 EEQ41708.1 - 0.099 12.9 0.4 0.15 12.4 0.4 1.6 1 1 0 1 1 1 0 Effector protein MBOAT PF03062.19 EEQ41709.1 - 1.4e-50 172.6 23.0 2.8e-50 171.6 23.0 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EEQ41709.1 - 0.0019 18.5 3.5 0.0019 18.5 3.5 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family WBS_methylT PF12589.8 EEQ41710.1 - 5.8e-12 46.2 7.1 1e-11 45.4 7.1 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EEQ41710.1 - 9.5e-12 45.4 0.0 2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EEQ41710.1 - 1.1e-09 38.9 0.0 3.3e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EEQ41710.1 - 1.6e-06 28.8 0.0 5.1e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EEQ41710.1 - 0.0004 20.3 0.0 0.0006 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.13 EEQ41710.1 - 0.00048 20.4 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 EEQ41710.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_L19 PF01245.20 EEQ41711.1 - 2.2e-06 27.6 0.3 4.2e-06 26.7 0.3 1.5 1 1 0 1 1 1 1 Ribosomal protein L19 DUF727 PF05303.12 EEQ41712.1 - 7.1e-10 38.9 1.0 1.1e-07 31.9 1.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF727) LSM PF01423.22 EEQ41713.1 - 5.8e-10 38.7 0.0 7.3e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EEQ41713.1 - 0.012 15.7 0.0 0.017 15.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain ESM4 PF15952.5 EEQ41714.1 - 0.035 14.5 0.5 0.051 14.0 0.5 1.2 1 0 0 1 1 1 0 Enhancer of split M4 family SAPS PF04499.15 EEQ41714.1 - 0.23 10.2 1.9 0.29 9.9 1.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4719 PF15843.5 EEQ41715.1 - 0.022 14.9 0.1 0.063 13.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) ABC_tran PF00005.27 EEQ41717.1 - 1e-45 155.6 0.3 2.9e-23 82.9 0.0 4.4 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 EEQ41717.1 - 8.7e-28 96.2 0.1 3.4e-27 94.3 0.1 2.2 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EEQ41717.1 - 4.5e-18 66.1 0.1 0.0043 16.9 0.0 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EEQ41717.1 - 6.3e-15 55.2 0.7 6.5e-05 22.5 0.1 4.3 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EEQ41717.1 - 1e-10 42.5 4.5 0.0014 19.2 0.1 3.6 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EEQ41717.1 - 1.3e-08 34.5 0.0 0.0082 15.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EEQ41717.1 - 4.9e-08 33.1 0.0 0.001 19.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EEQ41717.1 - 7.6e-08 32.4 0.1 0.003 17.6 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_28 PF13521.6 EEQ41717.1 - 1.8e-07 31.6 0.0 0.0019 18.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EEQ41717.1 - 8e-07 29.4 0.0 0.037 14.3 0.0 3.9 4 1 0 4 4 2 2 AAA domain AAA_18 PF13238.6 EEQ41717.1 - 1.2e-05 25.9 0.0 0.3 11.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EEQ41717.1 - 1.9e-05 25.0 0.0 0.19 12.2 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Dynamin_N PF00350.23 EEQ41717.1 - 1.9e-05 24.8 0.0 0.00094 19.3 0.0 3.1 2 0 0 2 2 2 1 Dynamin family AAA PF00004.29 EEQ41717.1 - 2.3e-05 24.8 0.0 0.63 10.5 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 EEQ41717.1 - 2.5e-05 23.4 0.1 0.11 11.5 0.0 2.8 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 EEQ41717.1 - 3.5e-05 24.0 0.0 0.23 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EEQ41717.1 - 4.2e-05 24.0 0.1 0.16 12.4 0.0 3.6 4 0 0 4 4 3 1 AAA ATPase domain MMS19_C PF12460.8 EEQ41717.1 - 5.2e-05 22.6 4.8 0.0082 15.3 0.2 2.5 3 0 0 3 3 2 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 EEQ41717.1 - 7.9e-05 22.8 5.4 0.0022 18.1 0.5 3.5 1 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 AAA_27 PF13514.6 EEQ41717.1 - 0.00026 20.7 0.0 0.28 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EEQ41717.1 - 0.00081 19.2 0.0 1.5 8.5 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EEQ41717.1 - 0.00088 19.0 0.1 1.2 8.8 0.0 3.1 4 0 0 4 4 2 1 AAA domain Adaptin_N PF01602.20 EEQ41717.1 - 0.00098 17.8 7.4 0.017 13.7 6.5 2.2 1 1 1 2 2 2 1 Adaptin N terminal region SbcCD_C PF13558.6 EEQ41717.1 - 0.0018 18.5 0.0 0.87 9.9 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.9 EEQ41717.1 - 0.0022 17.8 0.0 0.12 12.1 0.0 2.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 EEQ41717.1 - 0.0024 17.8 0.0 4.1 7.3 0.0 3.6 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EEQ41717.1 - 0.0025 17.8 0.0 0.74 9.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.6 EEQ41717.1 - 0.0038 17.2 0.0 6.2 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 EEQ41717.1 - 0.0059 16.6 0.0 3.5 7.5 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain CLP1_P PF16575.5 EEQ41717.1 - 0.0072 16.1 0.0 1.7 8.4 0.0 3.2 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop DUF87 PF01935.17 EEQ41717.1 - 0.011 15.9 7.8 0.38 10.8 0.0 4.5 6 0 0 6 6 3 0 Helicase HerA, central domain cobW PF02492.19 EEQ41717.1 - 0.011 15.3 0.0 5.7 6.5 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 EEQ41717.1 - 0.012 15.4 10.3 0.23 11.2 0.0 3.9 4 1 0 5 5 3 0 AAA ATPase domain IstB_IS21 PF01695.17 EEQ41717.1 - 0.013 15.2 0.0 3.9 7.2 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EEQ41717.1 - 0.016 14.6 0.1 2.6 7.4 0.0 3.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI CLASP_N PF12348.8 EEQ41717.1 - 0.017 14.7 1.5 0.24 10.9 1.3 2.3 1 1 1 2 2 2 0 CLASP N terminal Ploopntkinase3 PF18751.1 EEQ41717.1 - 0.02 14.8 0.0 4 7.3 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Roc PF08477.13 EEQ41717.1 - 0.023 14.9 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EEQ41717.1 - 0.024 13.9 0.2 9.4 5.5 0.0 3.4 4 0 0 4 4 3 0 Zeta toxin Cytidylate_kin PF02224.18 EEQ41717.1 - 0.03 14.1 0.0 9.7 5.9 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase ATP_bind_1 PF03029.17 EEQ41717.1 - 0.037 13.8 0.1 7.4 6.3 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EEQ41717.1 - 0.041 13.4 0.0 8.1 5.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Dopey_N PF04118.14 EEQ41717.1 - 0.081 12.0 0.1 0.19 10.8 0.1 1.6 1 0 0 1 1 1 0 Dopey, N-terminal TsaE PF02367.17 EEQ41717.1 - 0.083 12.9 0.0 6.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 EEQ41717.1 - 0.084 12.8 0.1 16 5.3 0.0 2.7 2 0 0 2 2 2 0 NTPase Septin PF00735.18 EEQ41717.1 - 0.09 12.0 0.0 3.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Septin ParcG PF10274.9 EEQ41717.1 - 0.093 12.8 0.8 4.8 7.3 0.1 3.1 1 1 2 3 3 3 0 Parkin co-regulated protein MukB PF04310.12 EEQ41717.1 - 0.1 12.4 0.0 11 5.8 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal MutS_V PF00488.21 EEQ41717.1 - 0.13 12.3 1.4 6.4 6.7 0.1 3.0 3 0 0 3 3 3 0 MutS domain V FeoB_N PF02421.18 EEQ41717.1 - 0.13 11.7 0.1 1.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_17 PF13207.6 EEQ41717.1 - 1.7 9.1 5.4 77 3.7 0.7 4.3 3 1 0 3 3 3 0 AAA domain ABC_tran_Xtn PF12848.7 EEQ41717.1 - 3.2 7.8 7.6 4.9 7.2 0.0 2.8 2 0 0 2 2 2 0 ABC transporter PLA2_B PF01735.18 EEQ41718.1 - 4.3e-114 381.6 13.9 1.8e-90 303.7 4.8 2.3 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.22 EEQ41718.1 - 0.00012 22.3 0.0 0.00044 20.5 0.0 1.8 2 1 0 2 2 2 1 Patatin-like phospholipase Ammonium_transp PF00909.21 EEQ41719.1 - 2e-74 250.7 26.1 1.1e-44 152.8 12.8 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Mito_carr PF00153.27 EEQ41720.1 - 2.4e-65 216.5 1.3 5.6e-21 74.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Erg28 PF03694.13 EEQ41721.1 - 2.8e-44 150.0 2.9 3.9e-44 149.5 2.9 1.2 1 0 0 1 1 1 1 Erg28 like protein cNMP_binding PF00027.29 EEQ41722.1 - 5.8e-43 144.9 0.2 1.7e-21 76.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.17 EEQ41722.1 - 4.7e-12 45.4 0.2 1.2e-11 44.0 0.2 1.7 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Cupin_2 PF07883.11 EEQ41722.1 - 0.042 13.6 0.3 0.55 10.0 0.0 2.4 2 0 0 2 2 2 0 Cupin domain HSP70 PF00012.20 EEQ41723.1 - 3.6e-258 857.7 14.5 4.1e-258 857.5 14.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EEQ41723.1 - 6.5e-17 61.3 1.5 7.8e-16 57.8 0.3 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EEQ41723.1 - 0.00069 20.0 7.7 1.8 9.0 0.1 3.9 3 2 0 3 3 3 3 Cell division protein FtsA Hydantoinase_A PF01968.18 EEQ41723.1 - 0.0052 16.1 2.3 0.073 12.3 0.2 2.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase DDR PF08841.10 EEQ41723.1 - 0.0088 15.1 3.6 0.035 13.1 1.7 2.6 1 1 1 2 2 2 1 Diol dehydratase reactivase ATPase-like domain CdiI_2 PF18593.1 EEQ41723.1 - 0.056 14.1 4.2 2.4 8.9 1.5 3.9 3 1 1 4 4 4 0 CdiI immunity protein FGGY_C PF02782.16 EEQ41723.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain HBS1_N PF08938.10 EEQ41723.1 - 0.25 11.7 5.9 1.4 9.3 5.8 2.3 1 1 0 1 1 1 0 HBS1 N-terminus DUF5053 PF16476.5 EEQ41723.1 - 0.29 10.8 2.0 22 4.8 0.0 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF5053) DUF4473 PF14747.6 EEQ41723.1 - 0.4 11.3 6.2 2.1 9.0 1.4 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) MobL PF18555.1 EEQ41723.1 - 0.44 9.8 14.0 0.28 10.4 8.5 2.4 2 1 0 2 2 2 0 MobL relaxases Not3 PF04065.15 EEQ41724.1 - 2.6e-34 118.6 8.4 2.6e-34 118.6 8.4 3.1 4 0 0 4 4 4 1 Not1 N-terminal domain, CCR4-Not complex component Pex2_Pex12 PF04757.14 EEQ41725.1 - 1.3e-47 162.3 13.2 1.3e-47 162.3 13.2 1.8 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EEQ41725.1 - 2.3e-07 30.8 1.3 4.7e-07 29.9 1.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EEQ41725.1 - 5e-06 26.4 1.1 1.1e-05 25.3 1.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EEQ41725.1 - 5.2e-06 26.2 2.2 5.9e-06 26.0 1.1 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EEQ41725.1 - 7.3e-06 25.7 0.5 1.4e-05 24.8 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EEQ41725.1 - 1.3e-05 24.9 1.1 2.7e-05 23.9 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EEQ41725.1 - 0.0037 17.6 0.9 0.0098 16.2 0.9 1.8 1 0 0 1 1 1 1 Ring finger domain FAM76 PF16046.5 EEQ41725.1 - 0.0038 16.6 2.6 0.0061 16.0 2.6 1.2 1 0 0 1 1 1 1 FAM76 protein E7 PF00527.18 EEQ41725.1 - 0.0043 17.2 1.2 0.95 9.7 0.6 2.5 2 0 0 2 2 2 1 E7 protein, Early protein TipE PF16972.5 EEQ41725.1 - 0.0086 15.3 1.1 0.013 14.8 1.1 1.1 1 0 0 1 1 1 1 Na+ channel auxiliary subunit TipE Prok-RING_4 PF14447.6 EEQ41725.1 - 0.24 11.3 3.4 0.28 11.1 1.4 2.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EEQ41725.1 - 0.38 10.8 2.5 2.2 8.3 2.8 2.0 1 1 1 2 2 2 0 zinc-RING finger domain IF-2B PF01008.17 EEQ41726.1 - 1e-53 182.4 0.1 1.8e-53 181.6 0.1 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family TMEM156 PF15106.6 EEQ41726.1 - 0.06 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 TMEM156 protein family Vps54 PF07928.12 EEQ41727.1 - 1.8e-37 128.8 1.1 1.8e-37 128.8 1.1 3.4 4 1 1 5 5 5 1 Vps54-like protein Thioredoxin_8 PF13905.6 EEQ41727.1 - 0.13 12.6 3.7 0.16 12.3 1.0 2.4 2 0 0 2 2 2 0 Thioredoxin-like DUF1462 PF07315.11 EEQ41727.1 - 0.13 12.5 1.2 0.63 10.4 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) CAT PF00302.18 EEQ41727.1 - 0.24 11.3 4.9 0.075 12.9 0.7 2.2 2 1 0 2 2 2 0 Chloramphenicol acetyltransferase COG2 PF06148.11 EEQ41727.1 - 0.43 10.7 6.7 0.17 12.0 1.5 3.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 COX17 PF05051.13 EEQ41728.1 - 1.1e-22 80.0 6.2 1.3e-22 79.9 6.2 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EEQ41728.1 - 0.0017 18.3 3.3 0.0068 16.4 0.0 2.0 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 EEQ41728.1 - 0.0023 18.0 3.3 0.0033 17.5 3.3 1.3 1 0 0 1 1 1 1 CHCH domain STIMATE PF12400.8 EEQ41729.1 - 8.5e-35 120.0 9.9 8.5e-35 120.0 9.9 1.6 2 0 0 2 2 2 1 STIMATE family DUF5389 PF17364.2 EEQ41729.1 - 0.035 14.1 0.2 0.13 12.3 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5389) LRR19-TM PF15176.6 EEQ41729.1 - 0.23 11.5 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain DUF1752 PF08550.10 EEQ41730.1 - 8.2e-12 44.7 3.3 1.8e-11 43.7 3.3 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) LicD PF04991.13 EEQ41731.1 - 1.7e-25 90.5 6.5 3.9e-20 73.0 0.2 2.9 3 1 1 4 4 4 2 LicD family Pkinase PF00069.25 EEQ41732.1 - 2.5e-46 158.2 0.0 2.9e-44 151.4 0.0 2.1 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41732.1 - 1.5e-25 89.9 0.0 3.2e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EEQ41732.1 - 0.00085 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EEQ41732.1 - 0.068 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Thioredoxin_7 PF13899.6 EEQ41733.1 - 4e-22 78.2 0.1 9.7e-22 77.0 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 EEQ41733.1 - 7.7e-12 44.8 1.4 1.5e-11 43.9 1.4 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EEQ41733.1 - 1.8e-10 40.9 0.0 4.6e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredoxin_2 PF13098.6 EEQ41733.1 - 0.043 14.3 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like domain Sds3 PF08598.11 EEQ41734.1 - 0.00025 21.1 6.5 0.00054 20.0 6.5 1.5 1 0 0 1 1 1 1 Sds3-like DUF2115 PF09888.9 EEQ41734.1 - 5.2 7.6 9.6 2.5 8.6 2.1 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) Skp1 PF01466.19 EEQ41735.1 - 3e-24 84.8 0.3 7.7e-24 83.6 0.3 1.7 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EEQ41735.1 - 1.8e-20 72.8 2.9 5.7e-20 71.3 2.9 1.9 1 1 0 1 1 1 1 Skp1 family, tetramerisation domain AbiEii PF08843.11 EEQ41735.1 - 0.063 13.2 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Peroxin-3 PF04882.12 EEQ41736.1 - 3.5e-97 326.3 16.5 1.9e-64 218.4 8.7 2.7 1 1 1 2 2 2 2 Peroxin-3 SurE PF01975.17 EEQ41737.1 - 1.3e-40 139.3 0.0 1.7e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE MF_alpha_N PF05436.11 EEQ41737.1 - 0.02 14.8 0.1 0.068 13.1 0.1 1.9 2 0 0 2 2 2 0 Mating factor alpha precursor N-terminus VASt PF16016.5 EEQ41738.1 - 5.1e-38 130.9 1.4 5.1e-38 130.9 1.4 1.9 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EEQ41738.1 - 2.4e-28 98.3 0.1 4.7e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 GRAM domain Ribonuc_2-5A PF06479.12 EEQ41739.1 - 1.2e-45 154.7 1.3 3.3e-45 153.4 1.3 1.8 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 EEQ41739.1 - 7e-38 130.5 0.0 1.9e-29 102.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EEQ41739.1 - 2.1e-22 79.6 0.0 5.1e-21 75.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EEQ41739.1 - 0.00015 21.5 0.0 0.18 11.8 0.0 3.0 3 0 0 3 3 3 2 PQQ enzyme repeat Pkinase_fungal PF17667.1 EEQ41739.1 - 0.0009 18.1 2.6 0.0055 15.5 0.0 2.6 2 1 1 3 3 3 1 Fungal protein kinase PQQ_2 PF13360.6 EEQ41739.1 - 0.0036 16.9 0.0 0.042 13.4 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.14 EEQ41739.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sas10_Utp3 PF04000.15 EEQ41740.1 - 6.5e-11 42.7 0.2 6.5e-11 42.7 0.2 2.2 1 1 1 2 2 2 1 Sas10/Utp3/C1D family CLZ PF16526.5 EEQ41740.1 - 0.013 15.9 1.2 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 EEQ41740.1 - 0.014 15.8 0.2 2.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cdh1_DBD_1 PF18196.1 EEQ41740.1 - 0.11 12.8 1.8 0.29 11.5 1.8 1.7 1 1 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 COG2 PF06148.11 EEQ41740.1 - 0.12 12.5 0.9 1.5 8.9 0.2 2.0 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LMBR1 PF04791.16 EEQ41740.1 - 0.18 10.7 0.3 0.18 10.6 0.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein SKA1 PF07160.12 EEQ41740.1 - 0.45 10.3 5.1 1.7 8.5 2.3 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF4200 PF13863.6 EEQ41740.1 - 0.75 10.2 8.0 2.5 8.5 4.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) EXS PF03124.14 EEQ41741.1 - 2.6e-68 230.8 23.5 3e-68 230.6 23.5 1.0 1 0 0 1 1 1 1 EXS family Ribonucleas_3_3 PF14622.6 EEQ41742.1 - 4.2e-06 26.9 0.1 0.00054 20.1 0.1 2.6 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EEQ41742.1 - 3.4e-05 24.4 0.3 0.00019 22.0 0.1 2.3 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 EEQ41742.1 - 0.005 17.5 0.0 0.018 15.8 0.0 2.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif VacA2 PF03077.14 EEQ41742.1 - 0.052 13.4 0.2 0.097 12.5 0.2 1.4 1 0 0 1 1 1 0 Putative vacuolating cytotoxin GARS_A PF01071.19 EEQ41743.1 - 4e-80 268.2 0.0 6.3e-80 267.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EEQ41743.1 - 3.7e-34 117.4 0.3 2.5e-33 114.7 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EEQ41743.1 - 6.6e-32 110.8 0.0 1.5e-31 109.7 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EEQ41743.1 - 4.6e-26 90.9 1.1 1.1e-25 89.7 1.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EEQ41743.1 - 2.5e-15 56.9 3.8 1.3e-14 54.6 3.8 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EEQ41743.1 - 3.1e-06 26.9 0.0 6.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EEQ41743.1 - 0.00099 19.2 0.1 0.0034 17.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EEQ41743.1 - 0.0015 18.0 0.1 0.0029 17.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 EEQ41743.1 - 0.17 11.5 0.3 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 RimK-like ATP-grasp domain GCS PF03074.16 EEQ41744.1 - 6.5e-155 516.0 0.0 8.1e-155 515.7 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase SMI1_KNR4 PF09346.10 EEQ41745.1 - 7.7e-27 94.3 0.0 1.5e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) ANAPC10 PF03256.16 EEQ41746.1 - 4.4e-46 156.9 0.1 2.4e-33 115.4 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) QRPTase_C PF01729.19 EEQ41747.1 - 8.2e-57 191.7 0.1 1e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EEQ41747.1 - 5.5e-15 55.2 0.0 3.2e-14 52.8 0.0 2.2 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain FMN_dh PF01070.18 EEQ41747.1 - 0.012 14.7 0.1 0.016 14.2 0.1 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase rve PF00665.26 EEQ41748.1 - 1.9e-19 70.0 0.0 2.5e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EEQ41748.1 - 3.3e-05 23.6 0.1 0.0001 22.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.14 EEQ41749.1 - 1.3e-76 257.5 0.3 1.7e-76 257.0 0.3 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EEQ41749.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) RSB_motif PF16294.5 EEQ41749.1 - 0.2 11.9 1.3 0.78 10.0 0.1 2.3 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif ATP-synt_S1 PF05827.12 EEQ41750.1 - 0.13 12.0 0.8 0.3 10.9 0.4 1.6 1 1 1 2 2 2 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Acetyltransf_13 PF13880.6 EEQ41751.1 - 7.9e-21 73.8 0.1 1.6e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EEQ41751.1 - 3.4e-11 42.8 0.1 5.3e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.7 EEQ41751.1 - 0.00011 22.6 0.0 0.00022 21.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EEQ41751.1 - 0.00013 22.2 0.0 0.0002 21.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EEQ41751.1 - 0.047 13.6 0.0 0.18 11.7 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 EEQ41752.1 - 1.1e-27 95.8 10.1 1.9e-10 40.5 0.3 4.0 3 2 0 3 3 3 3 Mitochondrial carrier protein RyR PF02026.16 EEQ41752.1 - 0.053 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 RyR domain CENP-T_C PF15511.6 EEQ41753.1 - 2.3e-11 43.8 0.2 5.9e-11 42.5 0.2 1.7 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EEQ41753.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 CENP-S protein GIDA PF01134.22 EEQ41754.1 - 4.6e-150 500.1 0.0 5.8e-150 499.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EEQ41754.1 - 2.1e-64 217.6 0.0 3.1e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EEQ41754.1 - 5.2e-05 22.8 1.2 5.2e-05 22.8 1.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EEQ41754.1 - 7.6e-05 22.1 4.6 0.0007 18.9 2.1 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EEQ41754.1 - 0.003 16.7 3.4 0.003 16.7 3.4 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EEQ41754.1 - 0.003 18.1 0.4 0.01 16.3 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EEQ41754.1 - 0.007 15.5 0.8 0.024 13.7 0.8 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EEQ41754.1 - 0.02 14.2 0.0 0.048 12.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EEQ41754.1 - 0.064 12.0 2.5 1.3 7.7 1.6 2.3 2 0 0 2 2 2 0 HI0933-like protein AlaDh_PNT_C PF01262.21 EEQ41754.1 - 0.084 12.2 0.5 0.17 11.2 0.5 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EEQ41754.1 - 0.11 11.7 1.3 0.71 9.1 1.3 2.1 1 1 0 1 1 1 0 Thi4 family DAO PF01266.24 EEQ41754.1 - 0.17 11.4 5.1 4.4 6.8 2.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EEQ41754.1 - 0.22 11.5 0.0 0.22 11.5 0.0 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EEQ41754.1 - 0.23 11.9 0.6 0.89 10.0 0.3 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding CMS1 PF14617.6 EEQ41755.1 - 8.9e-27 94.0 11.5 3e-26 92.3 11.5 1.7 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit PRP21_like_P PF12230.8 EEQ41755.1 - 0.18 11.7 12.3 0.64 9.9 0.1 2.5 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein Vps51 PF08700.11 EEQ41758.1 - 2.5e-13 49.9 0.4 1.5e-12 47.4 0.4 2.4 1 0 0 1 1 1 1 Vps51/Vps67 Zn_clus PF00172.18 EEQ41759.1 - 1.1e-06 28.6 10.9 1.9e-06 27.9 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4045 PF13254.6 EEQ41759.1 - 0.00071 19.3 0.6 0.00074 19.3 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4045) CBFB_NFYA PF02045.15 EEQ41760.1 - 5.2e-29 100.6 7.3 1.4e-28 99.2 7.3 1.8 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B DUF908 PF06012.12 EEQ41760.1 - 3.2 7.1 6.8 4 6.7 6.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CAS_CSE1 PF03378.15 EEQ41761.1 - 0.0026 16.3 0.0 0.0034 15.9 0.0 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus CAS_CSE1 PF03378.15 EEQ41762.1 - 1.6e-70 237.8 2.5 2.3e-70 237.3 2.5 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EEQ41762.1 - 2.9e-41 141.6 3.0 2.9e-41 141.6 3.0 1.8 2 0 0 2 2 2 1 Cse1 DUF3385 PF11865.8 EEQ41762.1 - 0.009 15.9 0.3 0.009 15.9 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) ACDC PF14733.6 EEQ41762.1 - 0.028 14.7 4.0 0.34 11.3 0.4 3.3 4 0 0 4 4 4 0 AP2-coincident C-terminal V-ATPase_H_N PF03224.14 EEQ41762.1 - 0.092 12.0 5.8 2.4 7.4 3.6 2.7 1 1 1 2 2 2 0 V-ATPase subunit H FPL PF09758.9 EEQ41762.1 - 0.15 12.1 8.3 1.8 8.6 1.1 3.3 2 2 1 3 3 3 0 Uncharacterised conserved protein Baculo_LEF-11 PF06385.12 EEQ41762.1 - 0.3 11.6 1.7 2.2 8.8 0.8 2.8 3 1 1 4 4 4 0 Baculovirus LEF-11 protein Pyridoxal_deC PF00282.19 EEQ41764.1 - 6e-59 199.6 0.0 8.6e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EEQ41764.1 - 1.4e-05 24.3 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Rota_NSP4 PF01452.16 EEQ41764.1 - 0.085 12.5 0.3 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 Rotavirus non structural protein CelTOS PF18659.1 EEQ41764.1 - 0.45 11.0 5.0 3.8 8.0 1.6 2.5 2 0 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites DUF1774 PF08611.10 EEQ41765.1 - 2.6e-30 104.6 6.4 2.6e-30 104.6 6.4 3.1 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) UPF0160 PF03690.13 EEQ41766.1 - 2.8e-134 447.7 0.0 3.2e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) zf-primase PF09329.11 EEQ41767.1 - 5.4e-11 42.1 1.7 1e-10 41.3 1.7 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.25 EEQ41767.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Malate_synthase PF01274.22 EEQ41767.1 - 0.02 13.2 0.4 0.031 12.5 0.4 1.3 1 0 0 1 1 1 0 Malate synthase Sec34 PF04136.15 EEQ41768.1 - 2.9e-35 121.4 5.1 2.9e-35 121.4 5.1 2.8 3 0 0 3 3 3 1 Sec34-like family BLOC1_2 PF10046.9 EEQ41768.1 - 0.0081 16.4 1.3 0.04 14.2 1.3 2.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 SesA PF17107.5 EEQ41768.1 - 0.028 14.6 1.8 0.82 9.9 0.1 3.0 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases KASH_CCD PF14662.6 EEQ41768.1 - 0.17 11.7 4.3 0.09 12.6 0.8 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH NPV_P10 PF05531.12 EEQ41768.1 - 0.22 12.0 4.7 0.21 12.1 0.8 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 EEQ41768.1 - 0.25 11.6 3.4 0.25 11.6 1.3 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Rep_fac_C PF08542.11 EEQ41768.1 - 0.4 11.1 1.8 29 5.2 0.0 4.1 4 0 0 4 4 4 0 Replication factor C C-terminal domain THOC7 PF05615.13 EEQ41768.1 - 0.63 10.3 3.0 3.8 7.8 0.3 2.8 2 0 0 2 2 2 0 Tho complex subunit 7 Tfb5 PF06331.12 EEQ41769.1 - 1.3e-24 85.9 0.1 1.7e-24 85.6 0.1 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Clathrin PF00637.20 EEQ41770.1 - 0.00025 20.9 1.7 0.00025 20.9 1.7 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.32 EEQ41770.1 - 0.00027 21.7 0.1 0.0013 19.6 0.1 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF846 PF05832.12 EEQ41771.1 - 1.3e-53 180.8 14.6 1.6e-53 180.5 14.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HnRNP_M PF11532.8 EEQ41771.1 - 0.13 12.5 1.1 1.1 9.5 0.2 2.2 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein M Cwf_Cwc_15 PF04889.12 EEQ41772.1 - 0.16 11.6 3.8 0.18 11.5 3.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DDE_1 PF03184.19 EEQ41773.1 - 2e-27 96.0 2.7 1.4e-26 93.2 2.7 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EEQ41773.1 - 4e-18 65.2 0.5 2.4e-17 62.7 0.2 2.5 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 EEQ41773.1 - 1.1e-06 28.3 0.0 3.6e-06 26.6 0.0 1.9 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain Hydrolase_4 PF12146.8 EEQ41774.1 - 1.7e-46 158.4 0.0 2.2e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EEQ41774.1 - 1.1e-19 71.1 0.0 1.1e-15 58.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EEQ41774.1 - 4.2e-13 50.4 0.0 5.2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EEQ41774.1 - 6.4e-08 32.5 0.1 0.0032 17.2 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EEQ41774.1 - 4.2e-06 26.7 0.0 0.0096 15.7 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF915 PF06028.11 EEQ41774.1 - 0.00021 20.7 0.2 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.7 EEQ41774.1 - 0.00054 19.0 0.0 0.0014 17.6 0.0 1.7 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 EEQ41774.1 - 0.00078 19.2 0.1 0.0018 18.1 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EEQ41774.1 - 0.0009 19.2 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EEQ41774.1 - 0.0074 16.2 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 EEQ41774.1 - 0.0096 15.6 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EEQ41774.1 - 0.021 14.9 0.0 0.046 13.8 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain DLH PF01738.18 EEQ41774.1 - 0.028 14.0 0.0 1.3 8.5 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family Chlorophyllase PF07224.11 EEQ41774.1 - 0.05 12.6 0.0 0.091 11.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase LIDHydrolase PF10230.9 EEQ41774.1 - 0.05 13.1 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 EEQ41774.1 - 0.061 12.8 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.8 EEQ41774.1 - 0.12 11.9 0.1 0.25 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) F-box-like PF12937.7 EEQ41775.1 - 2.4e-05 24.1 1.0 2.4e-05 24.1 1.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EEQ41775.1 - 0.012 15.5 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 EEQ41775.1 - 0.059 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box UPF0146 PF03686.13 EEQ41775.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) PP2C PF00481.21 EEQ41776.1 - 7.9e-67 225.6 0.1 9.3e-66 222.1 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EEQ41776.1 - 0.059 13.3 0.1 0.21 11.5 0.0 2.0 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) E1-E2_ATPase PF00122.20 EEQ41777.1 - 1.7e-44 151.5 2.1 2.5e-44 150.9 0.1 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EEQ41777.1 - 5.4e-36 124.9 0.3 9.4e-36 124.1 0.3 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EEQ41777.1 - 3.3e-14 53.1 9.1 2.8e-06 27.7 0.1 4.6 4 0 0 4 4 4 2 Heavy-metal-associated domain HAD PF12710.7 EEQ41777.1 - 0.0011 19.4 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EEQ41777.1 - 0.018 14.8 1.3 0.16 11.7 0.4 2.5 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase CorA PF01544.18 EEQ41777.1 - 0.11 11.8 0.0 0.41 9.9 0.0 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CTU2 PF10288.9 EEQ41777.1 - 0.68 10.2 3.4 2.5 8.4 3.3 2.0 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Scs3p PF10261.9 EEQ41778.1 - 3.8e-18 65.9 14.6 2.1e-14 53.6 3.9 2.3 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1129 PF06570.11 EEQ41778.1 - 0.64 9.5 5.7 0.8 9.2 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Abhydrolase_1 PF00561.20 EEQ41779.1 - 1.7e-45 155.7 0.1 7.1e-45 153.7 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EEQ41779.1 - 4.5e-05 23.2 0.1 7.9e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EEQ41779.1 - 0.017 15.7 0.0 0.025 15.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EEQ41779.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Erv26 PF04148.13 EEQ41780.1 - 3.8e-79 265.3 8.2 5.6e-79 264.7 8.2 1.2 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cyt_bd_oxida_II PF02322.15 EEQ41780.1 - 0.0058 16.0 7.0 0.0096 15.3 7.0 1.4 1 1 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II DUF2909 PF11137.8 EEQ41780.1 - 0.019 14.9 1.3 0.052 13.5 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) DUF996 PF06195.13 EEQ41780.1 - 0.087 13.1 4.6 0.12 12.6 3.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Vma12 PF11712.8 EEQ41780.1 - 0.5 10.4 3.8 2.3 8.3 0.7 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase TctB PF07331.11 EEQ41780.1 - 1.9 8.8 11.1 0.72 10.1 7.7 1.9 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family PLDc PF00614.22 EEQ41781.1 - 1.5e-16 59.8 0.3 3.2e-07 30.2 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EEQ41781.1 - 1.2e-12 47.9 0.0 1.6e-07 31.3 0.0 3.4 2 1 0 2 2 2 2 PLD-like domain DOPA_dioxygen PF08883.11 EEQ41782.1 - 2.9e-32 111.0 0.1 3.3e-32 110.9 0.1 1.0 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family MMR_HSR1 PF01926.23 EEQ41783.1 - 1.3e-15 57.4 0.0 3.1e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EEQ41783.1 - 3.7e-09 36.4 0.0 1e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EEQ41783.1 - 2.7e-06 27.0 0.0 4.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EEQ41783.1 - 1.4e-05 25.2 0.0 0.2 11.7 0.0 2.7 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 EEQ41783.1 - 2.7e-05 24.1 0.0 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EEQ41783.1 - 3.5e-05 23.3 0.0 6.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_33 PF13671.6 EEQ41783.1 - 4.5e-05 23.6 0.1 0.00061 20.0 0.1 2.3 1 1 0 1 1 1 1 AAA domain Septin PF00735.18 EEQ41783.1 - 0.0001 21.7 0.0 0.00017 20.9 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_22 PF13401.6 EEQ41783.1 - 0.017 15.4 0.0 0.041 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 EEQ41783.1 - 0.027 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 AIG1 family TniB PF05621.11 EEQ41783.1 - 0.035 13.5 0.1 0.078 12.4 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 EEQ41783.1 - 0.038 13.2 0.1 0.12 11.5 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 EEQ41783.1 - 0.057 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arf PF00025.21 EEQ41783.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family Roc PF08477.13 EEQ41783.1 - 0.074 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EEQ41783.1 - 0.14 11.5 0.1 0.36 10.1 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Gar1 PF04410.14 EEQ41784.1 - 4.7e-40 136.9 0.0 6.2e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region EF-hand_4 PF12763.7 EEQ41785.1 - 5e-33 113.2 0.0 3.8e-10 39.7 0.0 3.8 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.31 EEQ41785.1 - 1.4e-09 37.7 0.3 3.1e-09 36.6 0.3 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 EEQ41785.1 - 1e-07 31.0 0.1 6.1 6.6 0.0 5.4 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EEQ41785.1 - 9.2e-07 28.3 1.0 0.48 10.5 0.1 4.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 EEQ41785.1 - 1.5e-06 28.5 0.1 0.15 12.5 0.1 3.9 4 0 0 4 4 4 2 EF-hand domain pair DUF2613 PF11021.8 EEQ41785.1 - 0.0083 16.2 4.1 0.0083 16.2 4.1 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF2613) DUF3584 PF12128.8 EEQ41785.1 - 0.015 12.8 32.1 0.022 12.3 32.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CUE PF02845.16 EEQ41785.1 - 0.02 14.6 0.3 0.062 13.0 0.1 2.0 2 0 0 2 2 2 0 CUE domain UBA_2 PF08587.11 EEQ41785.1 - 0.043 13.9 0.4 1.1 9.5 0.0 3.0 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) UBA_3 PF09288.10 EEQ41785.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain EF-hand_8 PF13833.6 EEQ41785.1 - 0.089 12.7 0.1 24 4.9 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain pair MADF_DNA_bdg PF10545.9 EEQ41785.1 - 0.1 12.9 1.2 0.29 11.5 0.7 2.0 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1192 PF06698.11 EEQ41785.1 - 0.32 11.1 6.7 3.7 7.7 1.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF4201 PF13870.6 EEQ41785.1 - 0.56 9.9 34.1 0.24 11.1 16.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 EEQ41785.1 - 3 7.8 41.2 0.63 10.1 14.7 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.10 EEQ41785.1 - 3.8 7.9 23.7 2.6 8.4 2.0 3.7 2 1 1 3 3 3 0 Tup N-terminal TauD PF02668.16 EEQ41786.1 - 2.1e-59 201.5 1.7 2.9e-59 201.1 1.7 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family PhosphMutase PF10143.9 EEQ41786.1 - 0.059 13.2 0.0 0.093 12.6 0.0 1.3 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Zn_clus PF00172.18 EEQ41787.1 - 0.00023 21.2 13.4 0.00043 20.3 13.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HrpE PF06188.12 EEQ41788.1 - 0.085 12.7 0.3 15 5.4 0.0 2.4 2 0 0 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF2312 PF10073.9 EEQ41788.1 - 0.18 11.5 0.2 0.37 10.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) rve PF00665.26 EEQ41789.1 - 9.1e-22 77.5 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 EEQ41789.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain PRCC PF10253.9 EEQ41790.1 - 1.5 9.6 12.1 1.7 9.4 12.1 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting AA_permease_2 PF13520.6 EEQ41791.1 - 1.8e-89 300.5 38.3 2.2e-89 300.3 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EEQ41791.1 - 9.9e-18 64.0 34.0 1.4e-17 63.5 34.0 1.2 1 0 0 1 1 1 1 Amino acid permease DASH_Ask1 PF08655.10 EEQ41791.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 DASH complex subunit Ask1 KH_1 PF00013.29 EEQ41792.1 - 1.4e-68 226.7 25.3 5e-13 48.7 0.1 9.7 11 0 0 11 11 11 7 KH domain KH_2 PF07650.17 EEQ41792.1 - 3.8e-08 33.0 12.3 0.011 15.6 0.1 6.1 5 2 1 6 6 6 3 KH domain KH_4 PF13083.6 EEQ41792.1 - 7.8e-05 22.5 5.0 0.024 14.5 0.1 4.5 5 0 0 5 5 5 2 KH domain KH_5 PF13184.6 EEQ41792.1 - 0.0025 17.8 5.6 1.5 9.0 0.0 5.0 6 1 0 6 6 6 1 NusA-like KH domain Ribosomal_S10 PF00338.22 EEQ41792.1 - 0.022 15.0 0.4 2.8 8.2 0.0 3.0 1 1 1 2 2 2 0 Ribosomal protein S10p/S20e RACo_C_ter PF14574.6 EEQ41792.1 - 0.075 12.1 0.6 0.41 9.6 0.3 2.2 2 0 0 2 2 2 0 C-terminal domain of RACo the ASKHA domain HTH_Tnp_ISL3 PF13542.6 EEQ41792.1 - 0.22 11.0 1.1 3.4 7.2 0.0 3.0 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 SLS PF14611.6 EEQ41792.1 - 2.4 7.9 17.1 4.5 7.0 0.8 5.6 3 3 2 6 6 6 0 Mitochondrial inner-membrane-bound regulator KH_1 PF00013.29 EEQ41794.1 - 1.1e-10 41.1 8.1 7.2e-07 28.9 1.3 3.5 3 0 0 3 3 3 2 KH domain BMC PF00936.19 EEQ41794.1 - 0.12 12.4 1.1 3.7 7.6 0.0 2.5 2 0 0 2 2 2 0 BMC domain MIP-T3_C PF17749.1 EEQ41794.1 - 0.17 11.8 0.1 0.17 11.8 0.1 2.3 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region SH3BGR PF04908.15 EEQ41795.1 - 7e-07 29.3 0.1 1e-05 25.6 0.0 3.1 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EEQ41795.1 - 0.15 12.3 0.0 0.69 10.2 0.0 2.2 2 0 0 2 2 2 0 Glutaredoxin UQ_con PF00179.26 EEQ41796.1 - 1.7e-41 141.2 0.0 2.1e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EEQ41796.1 - 0.061 13.0 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B CAF1A PF12253.8 EEQ41796.1 - 2 8.7 13.1 3.7 7.8 13.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Dfp1_Him1_M PF08630.10 EEQ41798.1 - 1.3e-33 115.9 0.7 6.2e-33 113.7 0.0 2.5 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.12 EEQ41798.1 - 1.1e-21 76.6 2.9 2e-21 75.8 2.9 1.4 1 0 0 1 1 1 1 DBF zinc finger Phage_TAC_9 PF10876.8 EEQ41798.1 - 0.13 12.4 0.2 0.58 10.2 0.2 2.0 1 1 0 1 1 1 0 Phage tail assemb.y chaperone protein, TAC GTP_EFTU PF00009.27 EEQ41799.1 - 1.3e-32 112.9 5.0 2e-30 105.8 5.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EEQ41799.1 - 7.2e-28 96.8 0.4 2e-27 95.3 0.4 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 EEQ41799.1 - 4.1e-11 42.5 0.0 1.2e-10 41.1 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 EEQ41799.1 - 7.3e-09 35.7 0.1 2.3e-08 34.1 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EEQ41799.1 - 0.00016 21.2 0.1 0.00031 20.3 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 EEQ41799.1 - 0.0007 19.1 0.0 0.0017 17.8 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU_D4 PF14578.6 EEQ41799.1 - 0.0017 18.2 0.4 0.0081 16.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EEQ41799.1 - 0.0028 18.0 6.3 0.012 16.0 0.0 3.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1_Xtn PF16897.5 EEQ41799.1 - 0.0092 16.0 0.1 0.0092 16.0 0.1 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain GEN1_C PF18380.1 EEQ41799.1 - 0.029 15.3 2.5 0.029 15.3 2.5 2.3 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Ras PF00071.22 EEQ41799.1 - 0.037 13.6 0.1 0.093 12.3 0.1 1.7 1 0 0 1 1 1 0 Ras family RsgA_GTPase PF03193.16 EEQ41799.1 - 0.1 12.5 0.1 0.1 12.5 0.1 3.0 2 1 1 3 3 3 0 RsgA GTPase SRPRB PF09439.10 EEQ41799.1 - 0.18 11.2 7.9 0.039 13.4 0.5 2.9 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Membralin PF09746.9 EEQ41799.1 - 7.2 5.5 6.1 2.1 7.3 0.3 2.1 2 0 0 2 2 2 0 Tumour-associated protein PDCD2_C PF04194.13 EEQ41800.1 - 1.4e-36 126.1 5.9 7.7e-34 117.3 0.0 3.2 3 1 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain ThrE PF06738.12 EEQ41801.1 - 1.9e-65 220.6 5.1 1.9e-65 220.6 5.1 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EEQ41801.1 - 2.3e-05 24.5 10.9 2.3e-05 24.5 10.9 2.3 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE TauD PF02668.16 EEQ41802.1 - 1.1e-26 94.3 0.2 2.1e-26 93.3 0.1 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EEQ41802.1 - 0.00079 20.0 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) SH2_2 PF14633.6 EEQ41803.1 - 7.3e-75 251.1 0.5 2.6e-74 249.3 0.5 2.0 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 EEQ41803.1 - 2.3e-37 127.9 0.9 2.3e-37 127.9 0.9 2.8 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 YqgF PF14639.6 EEQ41803.1 - 1.4e-30 106.1 0.0 1.4e-30 106.1 0.0 2.7 3 0 0 3 3 3 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 EEQ41803.1 - 1.2e-27 96.3 0.0 4.2e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 EEQ41803.1 - 2.4e-22 79.3 21.0 2.4e-22 79.3 21.0 5.8 4 1 2 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.24 EEQ41803.1 - 3.9e-06 26.9 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 EEQ41803.1 - 4.8e-06 27.4 1.2 4.6e-05 24.2 0.1 3.4 2 0 0 2 2 2 1 HHH domain ArAE_2 PF10334.9 EEQ41803.1 - 0.026 14.3 0.1 0.2 11.4 0.0 2.3 2 0 0 2 2 2 0 Aromatic acid exporter family member 2 HHH_3 PF12836.7 EEQ41803.1 - 0.062 13.6 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif VPS9 PF02204.18 EEQ41805.1 - 6.5e-11 42.4 6.9 5.1e-10 39.5 6.9 2.4 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DER1 PF04511.15 EEQ41806.1 - 2.5e-17 63.5 14.1 6e-15 55.7 9.0 2.6 1 1 1 2 2 2 2 Der1-like family polyprenyl_synt PF00348.17 EEQ41807.1 - 7.3e-47 159.6 0.0 3.3e-25 88.6 0.0 2.0 2 0 0 2 2 2 2 Polyprenyl synthetase IBB PF01749.20 EEQ41808.1 - 0.0062 17.0 0.3 0.013 15.9 0.3 1.6 1 0 0 1 1 1 1 Importin beta binding domain Pab87_oct PF13969.6 EEQ41808.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Pab87 octamerisation domain TP_methylase PF00590.20 EEQ41809.1 - 1.8e-25 90.2 0.0 2.8e-25 89.5 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Per1 PF04080.13 EEQ41810.1 - 6e-96 321.1 12.4 9.3e-96 320.5 12.4 1.3 1 0 0 1 1 1 1 Per1-like family Aldolase_II PF00596.21 EEQ41811.1 - 2.3e-47 161.3 0.2 3.7e-47 160.7 0.2 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Clavispora_lusitaniae_ATCC_42720-ASM383v1/GCA_000003835.1_ASM383v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Clavispora_lusitaniae_ATCC_42720-ASM383v1/GCA_000003835.1_ASM383v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Clavispora_lusitaniae_ATCC_42720-ASM383v1/GCA_000003835.1_ASM383v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Clavispora_lusitaniae_ATCC_42720-ASM383v1/GCA_000003835.1_ASM383v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 16:25:13 2019 # [ok]