# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Rap_GAP PF02145.15 RKO94861.1 - 3.6e-33 114.7 0.0 4.2e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP NAM-associated PF14303.6 RKO94862.1 - 0.036 14.8 6.5 0.04 14.6 6.0 1.3 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain DNA_primase_lrg PF04104.14 RKO94863.1 - 9.1e-47 159.7 0.0 1.3e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit RNase_H2-Ydr279 PF09468.10 RKO94863.1 - 0.018 15.2 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Snf7 PF03357.21 RKO94864.1 - 6.5e-38 130.0 18.0 6.5e-38 130.0 18.0 1.3 2 0 0 2 2 2 1 Snf7 tRNA-synt_2 PF00152.20 RKO94864.1 - 0.12 11.4 1.6 0.1 11.6 0.3 1.5 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) Spc24 PF08286.11 RKO94864.1 - 1.2 9.5 4.4 2.8 8.2 3.8 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Asp_protease PF09668.10 RKO94865.1 - 1.6e-17 63.5 0.0 2.8e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 RKO94865.1 - 9.4e-09 34.9 0.0 1.3e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RKO94865.1 - 8.6e-05 22.3 0.1 0.00011 21.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like gag-asp_proteas PF13975.6 RKO94865.1 - 0.015 15.9 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Ubiquitin_4 PF18036.1 RKO94865.1 - 0.19 11.8 0.1 25 5.0 0.0 2.3 1 1 1 2 2 2 0 Ubiquitin-like domain Parvo_coat_N PF08398.10 RKO94866.1 - 0.02 15.0 0.2 0.02 15.0 0.2 1.6 2 0 0 2 2 2 0 Parvovirus coat protein VP1 ZnuA PF01297.17 RKO94867.1 - 0.082 12.3 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic DUF1397 PF07165.11 RKO94867.1 - 0.094 12.1 2.1 0.13 11.7 0.9 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1397) ETC_C1_NDUFA5 PF04716.14 RKO94867.1 - 0.3 10.9 4.8 1.1 9.1 0.1 2.9 2 1 1 3 3 3 0 ETC complex I subunit conserved region RRM_1 PF00076.22 RKO94868.1 - 1.6e-21 75.9 0.0 1.8e-21 75.8 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO94868.1 - 0.00024 21.1 0.0 0.00086 19.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 RKO94868.1 - 0.1 12.7 0.0 0.16 12.0 0.0 1.3 1 1 0 1 1 1 0 RNA binding motif PBD PF00786.28 RKO94869.1 - 2.8e-20 72.4 0.0 4.2e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 RKO94869.1 - 1.3e-13 51.3 0.5 1.8e-13 50.9 0.5 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 RKO94869.1 - 2.6e-05 24.6 2.0 0.00077 19.9 2.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 RKO94869.1 - 0.008 16.3 0.1 0.012 15.7 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_TFIIH PF08567.11 RKO94869.1 - 0.034 14.5 0.1 0.053 13.8 0.1 1.3 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain WD40 PF00400.32 RKO94870.1 - 4.6e-16 58.9 1.5 2e-05 25.3 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO94870.1 - 1.7e-05 25.1 0.1 0.24 11.7 0.1 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO94870.1 - 0.012 14.2 1.5 0.075 11.7 0.2 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKO94870.1 - 0.087 11.8 0.0 7 5.5 0.1 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Pirin_C PF05726.13 RKO94871.1 - 6.5e-26 90.7 0.0 2.5e-25 88.8 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.16 RKO94871.1 - 8.7e-26 90.0 0.1 1.5e-25 89.3 0.1 1.4 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.11 RKO94871.1 - 0.0008 19.1 0.1 0.2 11.4 0.3 2.6 3 0 0 3 3 3 2 Cupin domain STI1 PF17830.1 RKO94872.1 - 4e-15 55.5 6.4 5.2e-15 55.1 6.0 1.4 1 1 0 1 1 1 1 STI1 domain TPR_1 PF00515.28 RKO94872.1 - 0.0015 18.3 2.5 0.05 13.4 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ZYG-11_interact PF05884.12 RKO94872.1 - 0.033 13.6 1.3 0.04 13.3 1.3 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 TPR_14 PF13428.6 RKO94872.1 - 0.74 10.8 5.5 15 6.8 0.8 3.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Flot PF15975.5 RKO94872.1 - 1.1 9.4 9.9 3.7 7.8 9.9 1.8 1 1 0 1 1 1 0 Flotillin TPR_2 PF07719.17 RKO94872.1 - 4.3 7.7 7.1 3.1 8.2 0.2 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 RKO94872.1 - 6.3 7.4 9.6 2.8 8.5 4.0 2.8 2 2 1 3 3 3 0 Tetratricopeptide repeat KH_6 PF15985.5 RKO94873.1 - 6.1e-12 45.7 0.2 1.1e-11 44.9 0.2 1.5 1 0 0 1 1 1 1 KH domain Kinesin PF00225.23 RKO94874.1 - 9.4e-78 261.4 0.2 1.1e-77 261.3 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO94874.1 - 8.5e-28 97.2 0.1 1.2e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 RKO94874.1 - 0.099 11.8 0.5 0.19 10.9 0.3 1.5 1 1 0 1 1 1 0 PIF1-like helicase Acyl-CoA_dh_2 PF08028.11 RKO94876.1 - 0.068 13.4 2.9 0.099 12.9 2.9 1.2 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain Flu_M1_C PF08289.11 RKO94876.1 - 0.29 11.4 3.3 3.6 7.9 0.0 2.4 2 1 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Helicase_C_2 PF13307.6 RKO94878.1 - 2.2e-06 28.0 0.0 3.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain TFIID_30kDa PF03540.13 RKO94878.1 - 0.13 12.2 0.0 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Pkinase PF00069.25 RKO94879.1 - 6.3e-33 114.3 0.0 4.8e-32 111.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO94879.1 - 1e-20 74.2 0.0 1.2e-20 74.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO94879.1 - 0.00068 19.0 0.0 0.00073 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKO94879.1 - 0.00091 18.6 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO94879.1 - 0.019 14.9 0.1 0.027 14.4 0.1 1.3 1 1 0 1 1 1 0 Phosphotransferase enzyme family MARVEL PF01284.23 RKO94880.1 - 1.6e-15 57.4 8.6 2.5e-15 56.8 8.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain COX1 PF00115.20 RKO94880.1 - 0.074 11.9 5.7 0.04 12.8 3.3 1.6 1 1 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I DUF3177 PF11375.8 RKO94880.1 - 0.14 11.9 4.7 0.18 11.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3177) Viral_Beta_CD PF04530.12 RKO94880.1 - 0.5 10.7 1.8 0.58 10.5 0.1 2.1 1 1 2 3 3 3 0 Viral Beta C/D like family DUF2631 PF10939.8 RKO94880.1 - 0.5 10.2 1.9 2 8.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2631) Acetyltransf_1 PF00583.25 RKO94881.1 - 5.1e-10 39.6 0.1 6e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RKO94881.1 - 4.5e-07 30.2 0.2 5.6e-07 29.9 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKO94881.1 - 1.2e-05 25.2 0.1 1.4e-05 25.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_6 PF12774.7 RKO94883.1 - 7.3e-11 41.6 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 RKO94883.1 - 5.1e-10 39.5 0.0 1.2e-09 38.3 0.0 1.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RKO94883.1 - 3.9e-07 30.1 0.0 6.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKO94883.1 - 0.0026 18.0 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain LacI PF00356.21 RKO94883.1 - 0.0099 15.7 0.4 2.9 7.8 0.0 3.1 3 0 0 3 3 3 1 Bacterial regulatory proteins, lacI family AAA_30 PF13604.6 RKO94883.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RKO94883.1 - 0.021 15.2 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 RKO94883.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 RKO94883.1 - 0.053 13.7 0.0 0.096 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RKO94883.1 - 0.056 13.5 0.1 0.2 11.6 0.1 1.8 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 RKO94883.1 - 0.058 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.9 RKO94883.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 RKO94883.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 RKO94883.1 - 0.15 12.5 0.0 0.28 11.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 RKO94883.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DNA_ligase_A_M PF01068.21 RKO94884.1 - 1.4e-40 139.2 0.0 1.7e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 RKO94884.1 - 3.3e-26 91.8 0.0 6.3e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.6 RKO94884.1 - 0.18 11.8 0.2 7.6 6.6 0.0 2.5 2 0 0 2 2 2 0 DNA ligase OB-like domain PspA_IM30 PF04012.12 RKO94885.1 - 0.017 14.7 10.0 0.028 14.0 10.0 1.4 1 0 0 1 1 1 0 PspA/IM30 family DASH_Spc19 PF08287.11 RKO94885.1 - 0.11 12.4 1.9 0.26 11.2 1.8 1.7 1 1 0 1 1 1 0 Spc19 AAR2 PF05282.11 RKO94885.1 - 0.4 10.0 4.0 0.52 9.7 4.0 1.1 1 0 0 1 1 1 0 AAR2 protein DUF755 PF05501.11 RKO94885.1 - 0.48 10.7 6.6 0.83 9.9 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Hemerythrin PF01814.23 RKO94885.1 - 0.53 10.9 3.5 1.9 9.1 1.5 2.6 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF1822 PF08852.11 RKO94885.1 - 0.99 8.4 8.3 1.5 7.7 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Rab3-GTPase_cat PF13890.6 RKO94885.1 - 9.2 5.9 10.5 0.45 10.1 3.1 2.0 1 1 1 2 2 2 0 Rab3 GTPase-activating protein catalytic subunit NAD_binding_5 PF07994.12 RKO94886.1 - 1.2e-22 80.8 0.0 1.3e-22 80.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 RKO94886.1 - 0.0036 17.5 0.0 0.0092 16.2 0.0 1.6 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase DOR PF14839.6 RKO94887.1 - 0.057 13.4 0.9 0.057 13.4 0.9 1.9 2 0 0 2 2 2 0 DOR family WD40 PF00400.32 RKO94888.1 - 3.2e-24 84.7 1.5 2.6e-09 37.6 0.2 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO94888.1 - 2.3e-10 40.6 0.0 0.00035 20.8 0.0 2.9 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO94888.1 - 0.00023 20.3 0.2 0.073 12.0 0.1 2.1 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RKO94888.1 - 0.0043 16.9 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A DUF2415 PF10313.9 RKO94888.1 - 0.028 14.3 0.0 0.068 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Frtz PF11768.8 RKO94888.1 - 0.035 12.4 0.0 0.041 12.2 0.0 1.0 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Aminotran_1_2 PF00155.21 RKO94889.1 - 1.1e-66 225.4 0.0 1.3e-66 225.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Pro_isomerase PF00160.21 RKO94891.1 - 6.9e-46 156.4 0.0 7.7e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD COX1 PF00115.20 RKO94892.1 - 7.9e-11 41.5 0.8 9e-11 41.3 0.6 1.2 1 1 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I Ion_trans PF00520.31 RKO94892.1 - 0.032 13.5 0.9 0.046 13.0 0.9 1.3 1 1 0 1 1 1 0 Ion transport protein DUF3961 PF13106.6 RKO94892.1 - 0.24 11.0 0.4 0.24 11.0 0.4 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3961) Aa_trans PF01490.18 RKO94893.1 - 0.013 14.2 10.2 0.038 12.7 1.5 2.2 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein AAA PF00004.29 RKO94894.1 - 3.2e-31 108.5 0.0 4.6e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKO94894.1 - 4.8e-07 30.1 0.1 0.0012 19.1 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 RKO94894.1 - 1.2e-06 29.0 0.2 0.0014 19.1 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 RKO94894.1 - 6.1e-06 26.3 0.1 1.9e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RKO94894.1 - 8.6e-06 25.6 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 RKO94894.1 - 1.6e-05 24.7 0.0 2.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 RKO94894.1 - 0.00018 21.1 0.0 0.0021 17.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain TniB PF05621.11 RKO94894.1 - 0.00027 20.4 0.0 0.43 10.0 0.0 2.1 1 1 1 2 2 2 2 Bacterial TniB protein AAA_14 PF13173.6 RKO94894.1 - 0.00034 20.6 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKO94894.1 - 0.00051 20.2 0.0 0.0007 19.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RKO94894.1 - 0.00063 19.2 0.2 0.0016 17.8 0.2 1.5 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RKO94894.1 - 0.00064 19.0 0.2 0.0016 17.7 0.1 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 RKO94894.1 - 0.00068 19.8 0.0 0.001 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 RKO94894.1 - 0.00094 19.0 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 RKO94894.1 - 0.001 18.6 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_7 PF12775.7 RKO94894.1 - 0.0011 18.5 0.2 0.0057 16.2 0.2 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 RKO94894.1 - 0.0015 17.9 0.2 0.071 12.4 0.1 2.1 1 1 1 2 2 2 1 KaiC DUF815 PF05673.13 RKO94894.1 - 0.0018 17.5 0.0 0.0024 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 RKO94894.1 - 0.0093 16.1 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.6 RKO94894.1 - 0.012 16.2 0.0 0.017 15.7 0.0 1.4 1 1 0 1 1 1 0 AAA domain IFT46_B_C PF12317.8 RKO94894.1 - 0.015 15.1 0.0 0.019 14.7 0.0 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Sigma54_activat PF00158.26 RKO94894.1 - 0.021 14.5 0.0 0.035 13.8 0.0 1.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 RKO94894.1 - 0.028 14.6 0.0 0.04 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 RKO94894.1 - 0.032 14.2 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 RKO94894.1 - 0.033 14.6 0.0 0.062 13.7 0.0 1.5 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 RKO94894.1 - 0.039 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 RKO94894.1 - 0.04 13.0 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 RKO94894.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.6 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.6 RKO94894.1 - 0.054 13.2 0.2 0.07 12.8 0.2 1.4 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RKO94894.1 - 0.074 13.4 0.4 0.2 12.0 0.2 1.8 1 1 1 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RKO94894.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase DUF2075 PF09848.9 RKO94894.1 - 0.088 12.0 0.2 0.98 8.6 0.1 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Guanylate_kin PF00625.21 RKO94894.1 - 0.099 12.3 0.0 0.87 9.2 0.0 2.0 1 1 2 3 3 3 0 Guanylate kinase IPT PF01745.16 RKO94894.1 - 0.1 12.0 0.1 0.73 9.2 0.0 1.9 1 1 1 2 2 2 0 Isopentenyl transferase ATPase_2 PF01637.18 RKO94894.1 - 0.12 12.3 0.0 2.6 7.9 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_8 PF12780.7 RKO94894.1 - 0.15 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Mur_ligase_C PF02875.21 RKO94895.1 - 0.074 13.3 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Amelogenin PF02948.15 RKO94895.1 - 0.23 12.1 6.7 0.33 11.6 6.7 1.1 1 0 0 1 1 1 0 Amelogenin NUMOD1 PF07453.13 RKO94896.1 - 0.00013 22.1 0.4 0.00023 21.3 0.2 1.6 1 1 0 1 1 1 1 NUMOD1 domain DUF134 PF02001.16 RKO94896.1 - 0.064 13.8 0.1 0.069 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF134 DUF2492 PF10678.9 RKO94897.1 - 0.072 13.4 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2492) DUF2967 PF11179.8 RKO94897.1 - 4 5.4 10.2 6.4 4.7 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Njmu-R1 PF15053.6 RKO94898.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Mjmu-R1-like protein family PGAP1 PF07819.13 RKO94899.1 - 1.6e-43 149.1 0.0 3.9e-43 147.8 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 RKO94899.1 - 0.00029 20.2 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 RKO94899.1 - 0.00061 19.4 0.1 0.00095 18.7 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RKO94899.1 - 0.00072 20.2 8.3 0.00072 20.2 8.3 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 RKO94899.1 - 0.001 18.8 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 RKO94899.1 - 0.0032 17.3 0.0 0.0037 17.1 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 RKO94899.1 - 0.0054 16.6 0.1 0.0091 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.7 RKO94899.1 - 0.032 14.0 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Piwi PF02171.17 RKO94900.1 - 3.3e-37 128.4 0.0 4.3e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RKO94900.1 - 3.9e-13 49.4 0.0 6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 RKO94900.1 - 1.9e-06 28.1 0.0 4.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 RKO94900.1 - 0.0067 16.7 0.1 0.04 14.3 0.0 2.4 3 0 0 3 3 3 1 Argonaute linker 2 domain Pkinase PF00069.25 RKO94901.1 - 2.8e-70 236.7 0.0 3.3e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO94901.1 - 1.3e-35 122.9 0.0 1.7e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO94901.1 - 0.00014 21.3 0.5 0.00021 20.7 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKO94901.1 - 0.00027 20.0 0.1 0.00039 19.5 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKO94901.1 - 0.00071 19.6 0.5 0.02 14.8 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKO94901.1 - 0.051 12.9 0.1 0.74 9.1 0.0 2.2 1 1 1 2 2 2 0 Kinase-like HSP20 PF00011.21 RKO94904.1 - 2.2e-07 30.9 0.0 2.2e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 RKO94904.1 - 0.00015 21.2 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Nop53 PF07767.11 RKO94905.1 - 1.1e-15 57.9 4.3 1.5e-15 57.6 4.3 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) SR-25 PF10500.9 RKO94906.1 - 0.0031 17.2 7.7 0.0064 16.1 7.7 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein NAM-associated PF14303.6 RKO94906.1 - 8.4 7.1 8.8 18 6.0 8.8 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Macoilin PF09726.9 RKO94906.1 - 8.4 4.8 6.6 11 4.4 6.6 1.1 1 0 0 1 1 1 0 Macoilin family Hydrolase PF00702.26 RKO94907.1 - 8.8e-12 45.8 0.1 7.9e-09 36.1 0.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKO94907.1 - 3.1e-10 40.0 0.0 6.2e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 RKO94907.1 - 0.077 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 E1-E2 ATPase Septin PF00735.18 RKO94908.1 - 6.6e-108 360.3 0.0 9.1e-108 359.8 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 RKO94908.1 - 2.2e-07 31.0 0.0 4.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKO94908.1 - 1.1e-05 25.1 0.0 0.00039 20.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKO94908.1 - 4.1e-05 23.5 0.2 0.00054 19.9 0.2 2.4 2 1 0 2 2 2 1 RsgA GTPase Ras PF00071.22 RKO94908.1 - 4.8e-05 23.0 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Ras family Pox_A32 PF04665.12 RKO94908.1 - 0.0001 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 RKO94908.1 - 0.00016 21.9 0.0 0.00047 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.16 RKO94908.1 - 0.00046 19.6 0.0 0.00084 18.7 0.0 1.4 1 0 0 1 1 1 1 AIG1 family AAA_16 PF13191.6 RKO94908.1 - 0.0018 18.7 1.3 0.008 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Roc PF08477.13 RKO94908.1 - 0.0029 17.8 0.1 0.0087 16.3 0.1 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 RKO94908.1 - 0.011 14.8 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_25 PF13481.6 RKO94908.1 - 0.011 15.3 1.7 0.11 12.1 0.1 3.1 2 2 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 RKO94908.1 - 0.012 16.0 0.0 0.027 14.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 RKO94908.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 RKO94908.1 - 0.018 14.4 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_7 PF12775.7 RKO94908.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 RKO94908.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 RKO94908.1 - 0.082 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 RKO94908.1 - 0.1 12.3 0.1 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 RKO94908.1 - 0.15 11.9 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 RKO94908.1 - 0.18 11.5 0.0 2.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.23 RKO94908.1 - 0.37 10.8 3.5 4.7 7.2 0.1 2.7 2 1 1 3 3 2 0 Dynamin family DUF3845 PF12956.7 RKO94909.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure Zn_clus PF00172.18 RKO94911.1 - 0.0081 16.3 8.5 0.015 15.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 RKO94913.1 - 3.7e-30 103.5 10.2 3.1e-06 27.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Utp12 PF04003.12 RKO94913.1 - 6.8e-14 52.1 0.2 1.3e-13 51.1 0.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 RKO94913.1 - 1.2e-08 35.1 0.7 0.13 12.5 0.1 4.7 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO94913.1 - 0.00046 19.3 2.1 0.5 9.3 0.1 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RKO94913.1 - 0.0036 16.0 1.9 1.9 7.0 0.0 4.6 5 1 1 6 6 6 1 Nucleoporin Nup120/160 WD40_like PF17005.5 RKO94913.1 - 0.014 14.7 0.0 3.7 6.8 0.0 2.6 3 0 0 3 3 3 0 WD40-like domain Frtz PF11768.8 RKO94913.1 - 0.18 10.1 0.0 1.6 7.0 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ribosomal_L3 PF00297.22 RKO94914.1 - 2.4e-12 46.5 0.1 7.9e-12 44.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L3 Vps52 PF04129.12 RKO94915.1 - 7.1e-103 345.0 0.0 1e-101 341.2 0.0 2.1 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 RKO94915.1 - 3.2e-06 25.9 4.0 0.00031 19.3 0.7 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 ADH_N PF08240.12 RKO94916.1 - 1.5e-24 86.0 3.1 1.5e-24 86.0 3.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RKO94916.1 - 1.3e-17 64.0 0.0 2.6e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RKO94916.1 - 2.5e-08 33.7 0.0 5.2e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 RKO94916.1 - 5.5e-08 33.9 0.0 1.1e-07 33.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.19 RKO94916.1 - 0.00044 19.6 0.1 0.00073 18.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 RKO94916.1 - 0.00073 19.6 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 RKO94916.1 - 0.0035 17.9 0.0 0.0085 16.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 RKO94916.1 - 0.018 15.5 0.1 0.036 14.5 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 RKO94916.1 - 0.029 13.7 0.1 0.052 12.8 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 RKO94916.1 - 0.038 12.7 0.1 0.062 12.0 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Methyltransf_11 PF08241.12 RKO94916.1 - 0.041 14.5 0.1 0.11 13.1 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.14 RKO94916.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 RKO94916.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OST3_OST6 PF04756.13 RKO94917.1 - 3.9e-69 233.2 0.0 4.3e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family PhaG_MnhG_YufB PF03334.14 RKO94917.1 - 0.099 12.9 5.8 0.65 10.3 0.9 2.3 2 0 0 2 2 2 0 Na+/H+ antiporter subunit 7TMR-DISM_7TM PF07695.11 RKO94917.1 - 2.2 8.1 7.2 9.8 6.0 7.2 1.9 1 1 0 1 1 1 0 7TM diverse intracellular signalling RasGAP PF00616.19 RKO94918.1 - 6e-59 199.3 0.0 1.1e-58 198.4 0.0 1.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Tropomyosin_1 PF12718.7 RKO94918.1 - 0.081 13.1 0.8 0.15 12.2 0.8 1.4 1 0 0 1 1 1 0 Tropomyosin like FlxA PF14282.6 RKO94918.1 - 0.11 12.4 0.1 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 FlxA-like protein DSPc PF00782.20 RKO94920.1 - 0.00014 21.7 0.0 0.00019 21.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKO94920.1 - 0.0028 17.3 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase NUC153 PF08159.12 RKO94921.1 - 2.2e-05 24.2 3.3 4.4e-05 23.2 3.3 1.6 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 RKO94921.1 - 0.0014 18.8 0.0 0.015 15.6 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKO94921.1 - 0.0083 17.0 0.0 1.4 9.9 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 RKO94921.1 - 0.074 12.3 0.2 0.89 8.7 0.0 2.4 2 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Glyco_hydro_76 PF03663.14 RKO94922.1 - 4.1e-43 148.3 3.7 4.9e-43 148.0 3.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 RKO94922.1 - 0.023 13.8 3.8 1.2 8.2 0.0 3.3 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 TFIIA_gamma_N PF02268.16 RKO94924.1 - 1e-22 79.9 0.0 1.7e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 RKO94924.1 - 3.2e-16 59.2 0.1 4.7e-16 58.7 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.14 RKO94924.1 - 0.03 14.1 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase Proteasome PF00227.26 RKO94925.1 - 4.4e-51 173.1 0.2 5.1e-51 172.9 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit BBS2_Mid PF14783.6 RKO94925.1 - 0.049 13.7 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region Clat_adaptor_s PF01217.20 RKO94926.1 - 3.1e-19 69.3 0.1 3.8e-19 69.0 0.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Citrate_bind PF16114.5 RKO94926.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding RNase_PH PF01138.21 RKO94927.1 - 6.7e-09 36.3 0.3 9.7e-09 35.8 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RKO94927.1 - 5.5e-08 32.7 0.1 1.4e-07 31.5 0.0 1.8 2 1 0 2 2 2 1 3' exoribonuclease family, domain 2 TIP49 PF06068.13 RKO94928.1 - 4.9e-75 252.9 5.9 5.4e-75 252.8 5.9 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain DnaB_C PF03796.15 RKO94928.1 - 5.6e-07 29.2 1.2 7.3e-07 28.8 1.2 1.2 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA PF00004.29 RKO94928.1 - 2.2e-06 28.1 0.6 4.6e-06 27.1 0.6 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 RKO94928.1 - 7.9e-06 25.7 2.1 2.4e-05 24.1 1.5 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 RKO94928.1 - 0.0002 21.0 0.1 0.00037 20.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKO94928.1 - 0.00033 21.1 0.1 0.00035 21.0 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 RKO94928.1 - 0.00035 20.0 0.8 0.00053 19.4 0.8 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RKO94928.1 - 0.00092 19.2 0.1 0.002 18.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 RKO94928.1 - 0.006 15.9 0.1 0.0074 15.6 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 RKO94928.1 - 0.0067 15.7 1.7 0.013 14.8 0.4 2.0 2 0 0 2 2 2 1 Zeta toxin TsaE PF02367.17 RKO94928.1 - 0.0079 16.2 0.4 0.018 15.0 0.3 1.7 1 1 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 RKO94928.1 - 0.008 15.6 0.3 0.008 15.6 0.3 1.9 1 1 1 2 2 2 1 KaiC AAA_33 PF13671.6 RKO94928.1 - 0.0086 16.2 0.9 0.014 15.6 0.9 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 RKO94928.1 - 0.011 16.2 1.9 0.02 15.3 1.5 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RKO94928.1 - 0.011 16.0 1.0 0.016 15.4 0.2 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RKO94928.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 RKO94928.1 - 0.032 13.7 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 RKO94928.1 - 0.048 14.2 0.3 0.27 11.8 0.3 2.2 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKO94928.1 - 0.05 12.7 0.1 0.085 11.9 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 RKO94928.1 - 0.072 12.9 0.7 0.15 11.8 0.7 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 RKO94928.1 - 0.074 13.6 0.1 0.094 13.2 0.1 1.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 RKO94928.1 - 0.074 13.4 4.7 0.2 12.0 4.7 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 RKO94928.1 - 0.074 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 RKO94928.1 - 0.094 13.1 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Hydin_ADK PF17213.3 RKO94928.1 - 0.33 11.2 2.6 0.62 10.3 2.6 1.8 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain NTF2 PF02136.20 RKO94929.1 - 8.8e-13 48.9 0.1 9.5e-13 48.8 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Ribosomal_S6e PF01092.19 RKO94930.1 - 4.8e-54 181.7 0.3 1.1e-53 180.4 0.0 1.8 3 0 0 3 3 3 1 Ribosomal protein S6e tRNA-synt_2c PF01411.19 RKO94931.1 - 1.1e-52 179.3 0.1 1.2e-52 179.2 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (A) NYN PF01936.18 RKO94932.1 - 6.2e-11 43.0 0.0 8.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 NYN domain ECR1_N PF14382.6 RKO94933.1 - 6.9e-12 45.0 0.3 1.4e-11 44.0 0.3 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 RKO94933.1 - 0.0045 17.6 0.4 1.7 9.3 0.1 2.3 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 OSCP PF00213.18 RKO94934.1 - 1.5e-35 122.9 0.3 1.6e-35 122.8 0.3 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DnaJ PF00226.31 RKO94935.1 - 5e-19 68.2 0.9 8.2e-19 67.5 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain Peptidase_M24 PF00557.24 RKO94936.1 - 2.1e-42 145.2 0.9 9.2e-42 143.1 0.0 2.2 2 1 0 2 2 2 1 Metallopeptidase family M24 TRADD_N PF09034.10 RKO94936.1 - 0.088 12.9 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 TRADD, N-terminal domain Sdh5 PF03937.16 RKO94937.1 - 2.2e-28 98.0 0.2 2.8e-28 97.7 0.2 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Autophagy_N PF03986.13 RKO94938.1 - 9.9e-21 74.1 0.0 1.1e-11 44.9 0.0 2.5 2 0 0 2 2 2 2 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 RKO94938.1 - 4.9e-20 71.9 0.9 8.7e-20 71.1 0.9 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 RKO94938.1 - 1.2e-15 56.7 1.9 2.7e-15 55.5 1.9 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal TFIID_20kDa PF03847.13 RKO94939.1 - 4.6e-17 62.3 0.0 5e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 RKO94939.1 - 0.0053 16.8 0.0 0.0053 16.8 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 RKO94939.1 - 0.011 15.8 0.0 0.012 15.7 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 RKO94939.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.3 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 RKO94939.1 - 0.13 12.6 0.1 0.16 12.4 0.1 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 PGK PF00162.19 RKO94940.1 - 9.7e-97 324.3 0.3 1.1e-96 324.1 0.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Lipase_2 PF01674.18 RKO94941.1 - 1.6e-05 24.5 0.0 0.00043 19.9 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 2) DUF676 PF05057.14 RKO94941.1 - 0.03 13.8 0.0 0.04 13.4 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Palm_thioest PF02089.15 RKO94941.1 - 0.16 11.8 0.2 0.81 9.5 0.2 2.0 1 1 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 RKO94941.1 - 0.22 10.7 0.0 0.29 10.3 0.0 1.3 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase AAA_6 PF12774.7 RKO94942.1 - 2.6e-146 486.8 0.0 1.6e-145 484.2 0.0 2.3 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 RKO94942.1 - 7.5e-120 401.2 0.1 7.5e-120 401.2 0.1 4.1 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 RKO94942.1 - 4.6e-119 398.1 1.0 4.6e-119 398.1 1.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RKO94942.1 - 1.3e-86 290.2 0.0 7.8e-85 284.3 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKO94942.1 - 6.3e-84 280.5 0.1 2.5e-83 278.5 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region Dynein_C PF18199.1 RKO94942.1 - 4.2e-80 269.2 0.0 1.1e-79 267.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RKO94942.1 - 3.6e-60 202.6 0.3 5.4e-53 179.2 0.0 3.8 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKO94942.1 - 1.1e-52 178.2 0.1 3.9e-52 176.4 0.0 2.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RKO94942.1 - 2.5e-50 171.5 10.7 4.7e-50 170.6 10.7 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RKO94942.1 - 3.1e-41 140.2 0.0 2.8e-40 137.1 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RKO94942.1 - 1.9e-28 99.2 0.0 1.8e-11 44.2 0.0 5.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKO94942.1 - 1.1e-26 93.4 0.3 7.4e-26 90.7 0.1 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RKO94942.1 - 1.1e-14 54.5 0.0 5.1e-14 52.3 0.0 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 RKO94942.1 - 4.4e-10 40.0 1.1 0.13 12.5 0.0 5.7 5 0 0 5 5 4 3 AAA domain AAA PF00004.29 RKO94942.1 - 3.3e-09 37.3 0.1 0.3 11.5 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RKO94942.1 - 6.7e-06 26.5 0.1 1.7 9.0 0.0 4.4 4 0 0 4 4 4 2 RNA helicase Pox_A32 PF04665.12 RKO94942.1 - 1.6e-05 24.5 0.1 0.0012 18.3 0.0 2.9 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_16 PF13191.6 RKO94942.1 - 0.0001 22.7 16.3 0.56 10.6 0.0 8.6 8 1 0 8 8 7 2 AAA ATPase domain Sigma54_activat PF00158.26 RKO94942.1 - 0.00062 19.5 0.3 0.022 14.4 0.0 3.4 4 0 0 4 4 3 1 Sigma-54 interaction domain AAA_18 PF13238.6 RKO94942.1 - 0.0013 19.3 0.3 2.2 8.8 0.0 3.8 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.6 RKO94942.1 - 0.0015 18.2 1.0 7.1 6.2 0.0 4.3 4 0 0 4 4 3 0 AAA domain NACHT PF05729.12 RKO94942.1 - 0.0019 18.1 2.2 5.6 6.9 0.0 5.3 4 0 0 4 4 4 0 NACHT domain TsaE PF02367.17 RKO94942.1 - 0.0021 18.1 3.9 1.5 8.8 0.0 4.4 4 0 0 4 4 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 RKO94942.1 - 0.0023 17.7 3.1 7.5 6.2 0.0 3.8 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.15 RKO94942.1 - 0.0067 16.4 2.0 14 5.5 0.0 4.1 4 0 0 4 4 3 0 Rad17 P-loop domain Mg_chelatase PF01078.21 RKO94942.1 - 0.0096 15.3 0.7 3.5 6.9 0.0 4.2 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI DnaB_bind PF10410.9 RKO94942.1 - 0.018 15.2 2.8 2.3 8.5 0.0 4.1 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase ABC_tran PF00005.27 RKO94942.1 - 0.019 15.4 5.2 4.3 7.9 0.0 4.0 4 0 0 4 4 3 0 ABC transporter AAA_29 PF13555.6 RKO94942.1 - 0.025 14.3 0.3 3.2 7.6 0.0 3.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RKO94942.1 - 0.032 14.1 1.1 2.4 8.0 0.1 3.5 3 0 0 3 3 3 0 RsgA GTPase IstB_IS21 PF01695.17 RKO94942.1 - 0.055 13.2 0.3 19 4.9 0.0 3.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.6 RKO94942.1 - 0.058 13.6 1.4 13 5.9 0.0 4.3 4 0 0 4 4 4 0 AAA domain CCDC14 PF15254.6 RKO94942.1 - 0.06 12.0 12.3 0.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 14 Roc PF08477.13 RKO94942.1 - 0.092 13.0 0.3 33 4.7 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 RKO94942.1 - 0.16 11.1 0.3 5.9 6.0 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain ATP-synt_ab PF00006.25 RKO94942.1 - 0.2 11.3 0.1 3.1 7.4 0.0 2.6 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 RKO94942.1 - 0.21 11.3 1.0 72 3.0 0.0 4.0 4 0 0 4 4 3 0 AAA domain DASH_Duo1 PF08651.10 RKO94942.1 - 5.4 6.9 6.3 17 5.3 0.2 3.8 3 0 0 3 3 2 0 DASH complex subunit Duo1 PfkB PF00294.24 RKO94943.1 - 1.6e-68 231.2 0.1 1.9e-68 231.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ASFV_J13L PF05568.11 RKO94944.1 - 0.63 9.8 8.3 3.9 7.2 2.6 2.2 1 1 1 2 2 2 0 African swine fever virus J13L protein tRNA_bind PF01588.20 RKO94945.1 - 7.6e-29 99.7 0.0 1.1e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain Ribosomal_60s PF00428.19 RKO94945.1 - 7.3 7.3 13.7 13 6.4 13.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein tRNA-synt_1c PF00749.21 RKO94946.1 - 1.5e-110 369.0 0.2 2.1e-110 368.5 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 RKO94946.1 - 5e-33 114.4 0.2 1.3e-32 113.1 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 RKO94946.1 - 0.00023 21.3 0.0 0.00061 20.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 RKO94946.1 - 0.081 12.3 0.7 0.58 9.5 0.7 2.0 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain zf-Nse PF11789.8 RKO94947.1 - 4e-14 52.2 0.0 6.6e-14 51.5 0.0 1.3 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.20 RKO94947.1 - 0.00044 20.0 0.4 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 RKO94947.1 - 0.0025 17.8 0.1 0.0091 16.0 0.0 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Rtf2 PF04641.12 RKO94947.1 - 0.0028 17.1 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 RKO94947.1 - 0.0056 16.5 0.3 0.015 15.1 0.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKO94947.1 - 0.0061 16.7 0.4 0.013 15.6 0.0 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 RKO94947.1 - 0.03 14.5 0.0 0.3 11.3 0.0 1.9 1 1 1 2 2 2 0 U-box domain SURF6 PF04935.12 RKO94948.1 - 3.6e-23 82.4 36.0 3.6e-23 82.4 36.0 2.2 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 RKO94948.1 - 2.9e-12 47.0 0.5 2.9e-12 47.0 0.5 5.0 3 1 1 4 4 4 1 60S ribosome biogenesis protein Rrp14 Peptidase_M48_N PF16491.5 RKO94949.1 - 1.2e-42 145.9 7.3 1.5e-42 145.6 7.3 1.1 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 RKO94949.1 - 1.1e-18 67.8 0.0 1.6e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 DUF4538 PF15061.6 RKO94949.1 - 0.00072 19.2 2.2 0.0018 18.0 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4538) GtrA PF04138.14 RKO94949.1 - 0.062 13.5 3.7 0.09 13.0 3.7 1.3 1 0 0 1 1 1 0 GtrA-like protein Adaptin_N PF01602.20 RKO94950.1 - 8.7e-50 169.8 3.1 1e-49 169.5 3.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RKO94950.1 - 1.1e-44 152.4 0.4 1.1e-44 152.4 0.4 1.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKO94950.1 - 1.1e-12 48.1 4.5 2e-07 31.3 0.2 3.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 RKO94950.1 - 2e-07 30.7 3.1 0.37 11.2 0.0 3.8 3 0 0 3 3 3 3 HEAT repeat RTP1_C1 PF10363.9 RKO94950.1 - 7.5e-07 29.3 1.6 0.00025 21.2 0.4 3.2 1 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 RKO94950.1 - 0.00023 21.1 2.6 0.045 13.8 0.2 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.13 RKO94950.1 - 0.0049 16.4 0.0 0.011 15.2 0.0 1.7 1 1 0 1 1 1 1 Armadillo-like HEAT_EZ PF13513.6 RKO94950.1 - 0.02 15.4 8.7 2.5 8.7 0.4 4.3 4 1 1 5 5 4 0 HEAT-like repeat V-ATPase_H_N PF03224.14 RKO94950.1 - 0.034 13.4 0.4 0.12 11.6 0.3 2.0 1 1 1 2 2 2 0 V-ATPase subunit H V-ATPase_H_C PF11698.8 RKO94950.1 - 0.13 12.4 0.1 0.58 10.3 0.1 2.2 1 1 1 2 2 2 0 V-ATPase subunit H RasGEF_N_2 PF14663.6 RKO94950.1 - 0.37 11.2 1.7 5.2 7.5 0.1 3.0 1 1 3 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Profilin PF00235.19 RKO94951.1 - 6.2e-24 84.7 0.0 6.8e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Profilin RNA_pol_L_2 PF13656.6 RKO94952.1 - 2.3e-19 68.9 0.0 2.7e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 RKO94952.1 - 4.4e-05 22.8 0.0 5.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pescadillo_N PF06732.11 RKO94953.1 - 5.2e-36 124.6 0.1 5.2e-36 124.6 0.1 1.4 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 RKO94953.1 - 3.2e-12 46.7 0.0 5.4e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 RKO94953.1 - 0.00035 20.9 0.0 0.00082 19.7 0.0 1.7 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Sigma70_ner PF04546.13 RKO94953.1 - 0.19 11.6 3.7 0.3 10.9 0.1 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Atg8 PF02991.16 RKO94954.1 - 5.3e-45 151.9 0.0 6.6e-45 151.6 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 RKO94954.1 - 7.6e-06 26.2 0.0 9.9e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.12 RKO94954.1 - 0.024 14.2 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 GCS PF03074.16 RKO94955.1 - 3.1e-32 112.4 0.0 3.4e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Glutamate-cysteine ligase Pribosyl_synth PF14572.6 RKO94956.1 - 4.5e-32 111.6 0.6 5e-32 111.4 0.6 1.0 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 RKO94956.1 - 4.1e-06 26.4 0.2 5.1e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Ribosomal_S8e PF01201.22 RKO94957.1 - 8.8e-40 136.0 0.0 9.7e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e Cyclin PF08613.11 RKO94958.1 - 3.1e-05 24.4 0.0 3.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 RKO94958.1 - 0.0046 16.7 0.0 0.0053 16.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain E1-E2_ATPase PF00122.20 RKO94959.1 - 1.7e-07 30.9 1.0 2.1e-07 30.6 1.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase IstB_IS21 PF01695.17 RKO94959.1 - 0.012 15.3 0.0 0.015 15.1 0.0 1.0 1 0 0 1 1 1 0 IstB-like ATP binding protein Hydrolase PF00702.26 RKO94959.1 - 0.15 12.3 0.3 0.26 11.6 0.3 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 RKO94960.1 - 3e-35 121.9 0.2 3.5e-35 121.7 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO94960.1 - 8.2e-23 81.0 0.2 1e-22 80.7 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO94960.1 - 0.0018 17.7 0.0 0.0092 15.3 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 RKO94960.1 - 0.01 14.7 0.1 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RKO94960.1 - 0.014 15.4 0.0 0.71 9.7 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 RKO94960.1 - 0.15 11.4 0.1 0.95 8.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RKO94960.1 - 0.18 11.4 0.0 0.27 10.8 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Bromodomain PF00439.25 RKO94962.1 - 4.8e-17 61.8 0.1 7.5e-17 61.2 0.1 1.3 1 0 0 1 1 1 1 Bromodomain tRNA-synt_1b PF00579.25 RKO94963.1 - 4.4e-28 98.4 0.0 4.9e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) WD40 PF00400.32 RKO94964.1 - 4e-30 103.4 4.8 2e-09 37.9 0.2 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO94964.1 - 1.1e-11 44.8 0.0 0.0021 18.3 0.0 3.1 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RKO94964.1 - 0.00088 18.7 0.0 0.0016 17.9 0.0 1.5 1 1 0 1 1 1 1 WD40-like domain PALB2_WD40 PF16756.5 RKO94964.1 - 0.0018 17.3 0.0 0.15 10.9 0.0 2.6 1 1 2 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Nup160 PF11715.8 RKO94964.1 - 0.0023 16.7 0.1 0.027 13.1 0.0 2.4 1 1 2 3 3 3 1 Nucleoporin Nup120/160 PQQ PF01011.21 RKO94964.1 - 0.0045 16.8 0.0 0.87 9.6 0.0 3.3 3 1 0 3 3 3 1 PQQ enzyme repeat Ge1_WD40 PF16529.5 RKO94964.1 - 0.011 14.8 0.0 0.59 9.0 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 RKO94964.1 - 0.025 12.9 0.0 0.048 12.0 0.0 1.4 1 1 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz MORN_2 PF07661.13 RKO94964.1 - 0.11 12.7 0.0 13 6.4 0.0 3.0 2 0 0 2 2 2 0 MORN repeat variant Ribosomal_S8e PF01201.22 RKO94965.1 - 9.3e-42 142.4 1.2 1.1e-41 142.2 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e NAD_binding_1 PF00175.21 RKO94967.1 - 8.8e-27 93.9 0.0 1.2e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 RKO94967.1 - 2.9e-15 56.4 0.0 4.9e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 RKO94967.1 - 3e-05 24.2 0.0 6.9e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Pkinase PF00069.25 RKO94968.1 - 8.3e-31 107.3 0.0 8.9e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO94968.1 - 1.4e-07 31.1 0.0 1.4e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO94968.1 - 4.2e-05 23.0 0.0 5.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKO94968.1 - 0.00076 18.9 0.0 0.001 18.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKO94968.1 - 0.003 17.5 0.1 0.0034 17.3 0.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RKO94968.1 - 0.015 14.9 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 RKO94968.1 - 0.048 12.4 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 RKO94968.1 - 0.05 13.2 0.0 0.066 12.8 0.0 1.1 1 0 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 RKO94968.1 - 0.071 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SLAC1 PF03595.17 RKO94969.1 - 5.3e-32 111.4 15.0 5.8e-32 111.2 15.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CT_C_D PF02682.16 RKO94969.1 - 0.06 13.1 0.1 0.094 12.4 0.1 1.2 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D ANAPC10 PF03256.16 RKO94970.1 - 8.4e-28 97.3 0.0 9e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Ery_res_leader2 PF08057.11 RKO94970.1 - 0.1 13.0 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 Erythromycin resistance leader peptide PCNA_C PF02747.15 RKO94971.1 - 1.9e-38 131.5 0.0 2.2e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain ubiquitin PF00240.23 RKO94972.1 - 1.3e-15 56.9 0.0 1.4e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 RKO94972.1 - 9.8e-05 22.1 0.0 9.9e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RKO94972.1 - 0.0013 18.7 0.0 0.0014 18.5 0.0 1.0 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 RKO94972.1 - 0.0068 16.8 0.0 0.0073 16.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Pyr_redox_2 PF07992.14 RKO94973.1 - 2.1e-17 63.3 0.0 2.4e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO94973.1 - 1.7e-11 44.5 0.0 2.6e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKO94973.1 - 4.1e-08 32.8 0.0 4.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RKO94973.1 - 0.028 13.6 0.0 0.1 11.7 0.0 1.8 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 RKO94973.1 - 0.037 14.5 0.0 0.41 11.1 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding GTP_EFTU PF00009.27 RKO94974.1 - 8.2e-12 45.1 0.4 8.7e-12 45.0 0.4 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 RKO94974.1 - 0.016 14.4 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 RKO94974.1 - 0.1 11.9 0.4 0.14 11.5 0.4 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family ECH_1 PF00378.20 RKO94975.1 - 2.5e-54 184.3 1.4 2.7e-54 184.1 1.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RKO94975.1 - 2.7e-23 83.0 1.7 3e-23 82.9 1.7 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 RKO94975.1 - 0.06 13.3 0.1 0.15 12.0 0.0 1.6 2 0 0 2 2 2 0 Peptidase family S49 Aldedh PF00171.22 RKO94976.1 - 1.6e-45 155.5 0.0 1.9e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family YCII PF03795.14 RKO94976.1 - 0.098 13.1 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 YCII-related domain DUF883 PF05957.13 RKO94977.1 - 0.0093 16.5 10.9 0.0093 16.5 10.9 2.4 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) HTH_AsnC-type PF13404.6 RKO94977.1 - 0.13 12.1 2.1 0.35 10.7 0.5 2.2 1 1 1 2 2 2 0 AsnC-type helix-turn-helix domain YtxH PF12732.7 RKO94977.1 - 0.42 11.2 19.1 2.3e+02 2.4 19.1 3.2 1 1 0 1 1 1 0 YtxH-like protein HSP9_HSP12 PF04119.12 RKO94977.1 - 1.3 9.5 7.2 0.76 10.2 2.5 2.9 2 1 2 4 4 4 0 Heat shock protein 9/12 PFK PF00365.20 RKO94978.1 - 2.4e-10 40.2 0.1 3.1e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 Phosphofructokinase Actin PF00022.19 RKO94979.1 - 3.5e-26 91.8 0.0 3.7e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Actin Tubulin PF00091.25 RKO94980.1 - 2.9e-46 158.2 0.0 3.2e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 RKO94980.1 - 0.0068 16.1 0.0 0.0076 15.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RKO94980.1 - 0.064 12.4 0.0 0.07 12.3 0.0 1.1 1 0 0 1 1 1 0 Tubulin like GRAS PF03514.14 RKO94980.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 GRAS domain family Gelsolin PF00626.22 RKO94981.1 - 9.9e-05 22.2 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Gelsolin repeat Mpp10 PF04006.12 RKO94982.1 - 5.2e-14 51.6 8.1 6e-14 51.4 8.1 1.0 1 0 0 1 1 1 1 Mpp10 protein LZ_Tnp_IS66 PF13007.7 RKO94982.1 - 2 9.3 4.4 40 5.1 4.4 2.4 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain CPSase_L_D2 PF02786.17 RKO94983.1 - 1e-27 97.1 0.3 5e-14 52.3 0.2 2.0 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain TFA2_Winged_2 PF18121.1 RKO94984.1 - 5.3e-17 61.3 0.2 1.3e-16 60.1 0.1 1.6 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 RKO94984.1 - 7e-07 29.4 0.7 1.6e-06 28.3 0.7 1.6 1 0 0 1 1 1 1 TFIIE beta subunit core domain Ank_4 PF13637.6 RKO94985.1 - 4.9e-06 27.0 4.6 0.00015 22.2 0.8 1.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) PCM1_C PF15717.5 RKO94985.1 - 0.03 13.0 0.1 0.035 12.8 0.1 1.0 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Ank_5 PF13857.6 RKO94985.1 - 0.051 13.9 1.0 0.23 11.8 0.3 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) GST_N PF02798.20 RKO94986.1 - 4.9e-08 33.2 0.0 5.2e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RKO94986.1 - 0.0068 16.8 0.0 0.0074 16.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 RKO94986.1 - 0.11 12.8 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Pyr_redox_2 PF07992.14 RKO94988.1 - 5.8e-09 35.6 0.0 6.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RRS1 PF04939.12 RKO94989.1 - 2.8e-28 98.8 4.5 3.1e-28 98.7 4.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) BPL_LplA_LipB PF03099.19 RKO94990.1 - 0.0015 18.4 0.1 0.0016 18.3 0.1 1.1 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family ABC_membrane PF00664.23 RKO94991.1 - 3.9e-13 49.7 0.4 4.9e-13 49.4 0.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region HA2 PF04408.23 RKO94992.1 - 5.6e-12 45.9 0.0 8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 RKO94993.1 - 2.5e-06 27.8 0.0 6e-05 23.3 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain PH_17 PF18012.1 RKO94993.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 PH domain CMAS PF02353.20 RKO94995.1 - 1.3e-20 73.9 0.1 1.9e-20 73.3 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 RKO94995.1 - 0.0017 18.2 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKO94995.1 - 0.0039 16.8 0.1 0.0052 16.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RKO94995.1 - 0.021 15.5 0.1 0.037 14.7 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 RKO94995.1 - 0.031 13.7 0.1 0.052 12.9 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 RKO94995.1 - 0.035 14.2 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase CRAL_TRIO PF00650.20 RKO94996.1 - 2.2e-22 79.5 0.0 2.4e-22 79.3 0.0 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain SPX PF03105.19 RKO94997.1 - 5.8e-10 39.6 2.9 6.7e-07 29.6 0.2 2.0 1 1 1 2 2 2 2 SPX domain PQ-loop PF04193.14 RKO94998.1 - 2.7e-10 39.9 0.1 2.9e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 PQ loop repeat IML1 PF12257.8 RKO94999.1 - 2e-29 102.6 0.1 2.4e-29 102.4 0.1 1.1 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Slu7 PF11708.8 RKO95000.1 - 0.00019 21.3 0.3 0.00019 21.3 0.3 1.4 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 RKO95000.1 - 0.004 16.9 0.5 0.007 16.1 0.5 1.4 1 0 0 1 1 1 1 Zinc knuckle Sigma70_r2 PF04542.14 RKO95000.1 - 0.053 13.3 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Sigma-70 region 2 CPSF_A PF03178.15 RKO95001.1 - 8.9e-28 97.5 0.0 9.6e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 CPSF A subunit region Cpn60_TCP1 PF00118.24 RKO95003.1 - 1.4e-38 132.8 0.3 1.6e-38 132.6 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 RKO95003.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) Hydrolase_3 PF08282.12 RKO95004.1 - 2.8e-24 86.3 0.0 2.9e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 RKO95004.1 - 7.5e-09 35.5 0.0 8.4e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase HAD PF12710.7 RKO95004.1 - 0.0016 18.9 0.0 0.0024 18.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RKO95004.1 - 0.032 14.5 0.1 0.048 14.0 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tubulin PF00091.25 RKO95005.1 - 1.1e-30 107.3 0.0 1.2e-30 107.2 0.0 1.0 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain CAP_C PF08603.11 RKO95007.1 - 6.4e-33 113.6 4.8 7e-33 113.5 4.8 1.0 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Yop-YscD_cpl PF16697.5 RKO95007.1 - 0.044 14.1 0.1 0.05 13.9 0.1 1.1 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain TBCC PF07986.12 RKO95007.1 - 0.071 12.8 2.7 0.094 12.5 2.7 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor C TGBp3 PF02495.17 RKO95007.1 - 0.53 10.0 3.7 0.34 10.6 1.3 1.9 2 0 0 2 2 2 0 Triple gene block 3 Lipase_3 PF01764.25 RKO95008.1 - 2.2e-07 30.8 0.0 3.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 RKO95008.1 - 0.013 16.1 1.1 0.014 16.0 0.8 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 RKO95008.1 - 0.029 13.6 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 RKO95008.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 RKO95008.1 - 0.13 12.3 0.1 0.18 11.9 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF5075 PF16825.5 RKO95009.1 - 0.15 11.7 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 IGP family C-type lectin domain DEAD PF00270.29 RKO95010.1 - 1.3e-27 96.7 0.0 1.4e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase SNF2_N PF00176.23 RKO95010.1 - 0.14 10.8 0.0 0.14 10.8 0.0 1.0 1 0 0 1 1 1 0 SNF2 family N-terminal domain CMS1 PF14617.6 RKO95010.1 - 0.15 11.4 0.0 0.18 11.1 0.0 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 RKO95010.1 - 0.16 12.0 0.0 0.17 11.9 0.0 1.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ribonuc_red_sm PF00268.21 RKO95011.1 - 5.4e-40 137.6 0.0 6.5e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain LRR19-TM PF15176.6 RKO95012.1 - 0.016 15.2 1.8 0.018 15.1 0.8 1.6 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain Ufd2P_core PF10408.9 RKO95013.1 - 3.7e-34 118.4 0.5 1.1e-31 110.2 0.5 2.0 1 1 0 1 1 1 1 Ubiquitin elongating factor core Med12 PF09497.10 RKO95013.1 - 0.16 12.3 0.3 0.4 11.0 0.3 1.8 1 1 0 1 1 1 0 Transcription mediator complex subunit Med12 GCV_T PF01571.21 RKO95014.1 - 2.1e-41 142.0 0.1 2.4e-41 141.8 0.1 1.0 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.12 RKO95014.1 - 0.0033 17.6 0.1 0.0039 17.3 0.1 1.2 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Sec63 PF02889.16 RKO95015.1 - 0.064 12.4 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 Sec63 Brl domain DUF4514 PF14986.6 RKO95016.1 - 0.15 12.1 0.3 0.3 11.1 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) Peptidase_M28 PF04389.17 RKO95017.1 - 4.4e-21 75.5 0.0 5.2e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M28 zf-C3HC4 PF00097.25 RKO95018.1 - 3.2e-07 30.1 10.1 5.2e-07 29.4 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKO95018.1 - 1.2e-06 28.2 9.4 1.9e-06 27.6 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO95018.1 - 7.8e-06 25.8 4.4 8.3e-06 25.7 3.0 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 RKO95018.1 - 1.3e-05 25.1 9.8 2e-05 24.5 9.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RKO95018.1 - 8e-05 22.4 9.8 0.00024 20.9 9.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO95018.1 - 8.2e-05 22.9 8.4 0.00013 22.2 8.4 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 RKO95018.1 - 0.00043 20.1 6.9 0.0012 18.7 6.9 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RKO95018.1 - 0.76 10.0 11.2 1.4 9.2 11.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_Tnp_IS91 PF14319.6 RKO95018.1 - 1 9.4 8.8 0.6 10.2 6.3 1.8 1 1 1 2 2 2 0 Transposase zinc-binding domain GTP_EFTU PF00009.27 RKO95019.1 - 3.4e-61 206.2 1.9 3.7e-61 206.0 1.9 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKO95019.1 - 1.9e-05 24.7 0.2 3e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RKO95019.1 - 0.059 12.8 0.1 0.1 12.0 0.1 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RKO95019.1 - 0.12 12.2 1.5 2 8.3 0.1 2.6 2 1 0 2 2 2 0 RsgA GTPase SF1-HH PF16275.5 RKO95020.1 - 1.7e-26 92.8 0.7 2.4e-26 92.3 0.7 1.2 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 RKO95020.1 - 6.9e-06 25.8 0.2 1.3e-05 25.0 0.2 1.5 1 0 0 1 1 1 1 KH domain Caudo_TAP PF02413.17 RKO95020.1 - 0.11 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK Tim17 PF02466.19 RKO95021.1 - 2.5e-11 44.0 0.1 3.2e-11 43.6 0.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PFK PF00365.20 RKO95022.1 - 7.6e-44 150.1 0.0 8.4e-44 150.0 0.0 1.0 1 0 0 1 1 1 1 Phosphofructokinase EMC3_TMCO1 PF01956.16 RKO95023.1 - 6.5e-34 117.1 3.9 7.8e-34 116.9 3.9 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like PAPS_reduct PF01507.19 RKO95024.1 - 6e-22 78.5 0.0 7.3e-20 71.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RVP_2 PF08284.11 RKO95025.1 - 0.0083 15.9 0.0 0.0085 15.9 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 RKO95025.1 - 0.099 13.2 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease AAA PF00004.29 RKO95027.1 - 2.5e-36 125.0 0.0 3.2e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO95027.1 - 6.7e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKO95027.1 - 3.5e-07 30.3 0.0 1.3e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO95027.1 - 4.1e-07 30.5 1.1 8.2e-05 23.0 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 RKO95027.1 - 1e-06 29.0 0.5 0.00083 19.6 0.4 2.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 RKO95027.1 - 2.3e-06 27.4 0.0 5e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 RKO95027.1 - 8.3e-06 26.2 0.0 0.00027 21.3 0.0 2.2 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 RKO95027.1 - 8.3e-06 25.9 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKO95027.1 - 3.6e-05 24.3 0.0 4.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKO95027.1 - 5.6e-05 23.3 0.0 8.7e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RKO95027.1 - 0.0001 22.0 0.4 0.02 14.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 RKO95027.1 - 0.00024 20.6 0.2 0.00091 18.7 0.1 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 RKO95027.1 - 0.00039 20.4 0.1 0.0051 16.8 0.0 2.1 1 1 1 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 RKO95027.1 - 0.00052 19.8 0.0 0.00076 19.3 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TniB PF05621.11 RKO95027.1 - 0.00064 19.2 0.1 0.72 9.2 0.0 2.3 1 1 1 2 2 2 2 Bacterial TniB protein Bac_DnaA PF00308.18 RKO95027.1 - 0.00071 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial dnaA protein Rad17 PF03215.15 RKO95027.1 - 0.00098 19.1 0.1 0.0038 17.2 0.0 1.7 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_2 PF07724.14 RKO95027.1 - 0.0017 18.5 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.6 RKO95027.1 - 0.0018 18.4 0.0 0.0037 17.4 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.6 RKO95027.1 - 0.0022 18.2 0.0 0.0044 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 RKO95027.1 - 0.0031 17.4 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.6 RKO95027.1 - 0.0034 17.1 0.0 0.0068 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 RKO95027.1 - 0.0048 16.1 0.0 0.0065 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_21 PF13304.6 RKO95027.1 - 0.0049 16.7 0.1 0.6 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Guanylate_kin PF00625.21 RKO95027.1 - 0.0056 16.4 0.0 0.31 10.7 0.0 2.7 1 1 1 3 3 3 1 Guanylate kinase Zeta_toxin PF06414.12 RKO95027.1 - 0.0073 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_7 PF12775.7 RKO95027.1 - 0.009 15.5 0.0 0.013 15.0 0.0 1.4 1 1 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 RKO95027.1 - 0.0094 16.5 0.0 0.011 16.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter ATPase_2 PF01637.18 RKO95027.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 RKO95027.1 - 0.016 14.4 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 RKO95027.1 - 0.022 14.7 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 RKO95027.1 - 0.025 15.0 0.1 0.053 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKO95027.1 - 0.027 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 RKO95027.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain tRNA_lig_kinase PF08303.11 RKO95027.1 - 0.034 14.2 0.0 0.052 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA ligase kinase domain AAA_3 PF07726.11 RKO95027.1 - 0.035 14.0 0.0 0.043 13.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 RKO95027.1 - 0.05 12.9 0.1 0.88 8.9 0.0 2.1 1 1 1 2 2 2 0 KaiC SKI PF01202.22 RKO95027.1 - 0.072 13.2 0.1 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase Viral_helicase1 PF01443.18 RKO95027.1 - 0.082 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 RKO95027.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IPT PF01745.16 RKO95027.1 - 0.14 11.5 0.1 0.42 10.0 0.0 1.7 2 1 0 2 2 1 0 Isopentenyl transferase AAA PF00004.29 RKO95028.1 - 1.5e-11 44.9 0.0 1.7e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKO95028.1 - 3.3e-06 27.6 0.2 3.4e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 RKO95028.1 - 9.9e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 RKO95028.1 - 0.00029 20.9 0.0 0.00034 20.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 RKO95028.1 - 0.00046 20.0 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 RKO95028.1 - 0.0015 18.0 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 RKO95028.1 - 0.003 17.8 0.1 0.035 14.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 RKO95028.1 - 0.0043 16.3 0.0 0.0046 16.2 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 RKO95028.1 - 0.0092 16.5 0.0 0.011 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 RKO95028.1 - 0.0093 15.9 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain TIP49 PF06068.13 RKO95028.1 - 0.013 14.8 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_24 PF13479.6 RKO95028.1 - 0.016 15.0 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 RKO95028.1 - 0.016 14.5 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 AAA_6 PF12774.7 RKO95028.1 - 0.027 13.5 0.0 0.033 13.2 0.0 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_2 PF07724.14 RKO95028.1 - 0.031 14.4 0.0 0.038 14.1 0.0 1.0 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 RKO95028.1 - 0.04 14.3 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 RKO95028.1 - 0.04 13.8 0.1 0.21 11.5 0.1 2.0 1 1 0 1 1 1 0 NACHT domain DEAD PF00270.29 RKO95028.1 - 0.044 13.5 0.5 0.94 9.2 0.0 2.1 1 1 1 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.15 RKO95028.1 - 0.047 13.6 0.1 0.19 11.6 0.0 1.8 1 1 1 2 2 2 0 NTPase AAA_7 PF12775.7 RKO95028.1 - 0.048 13.2 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region UPF0160 PF03690.13 RKO95029.1 - 8.1e-41 140.7 0.5 8.9e-41 140.5 0.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Hist_deacetyl PF00850.19 RKO95031.1 - 1.3e-10 41.2 0.0 1.5e-10 41.0 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Sec1 PF00995.23 RKO95032.1 - 0.00019 20.8 0.3 0.0002 20.7 0.3 1.0 1 0 0 1 1 1 1 Sec1 family TFIIB PF00382.19 RKO95033.1 - 5.8e-29 100.0 0.0 2.1e-17 62.9 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.23 RKO95033.1 - 0.016 15.0 0.0 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Cyclin, N-terminal domain HTH_AsnC-type PF13404.6 RKO95033.1 - 0.077 12.8 0.3 0.3 11.0 0.1 2.0 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Ribosomal_S8 PF00410.19 RKO95034.1 - 3.1e-11 43.3 0.0 5.8e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L5e PF17144.4 RKO95035.1 - 2.2e-63 213.1 0.0 2.7e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 RKO95035.1 - 2.8e-12 47.4 0.2 4.1e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L18 C-terminal region RNA_pol_Rpb2_6 PF00562.28 RKO95037.1 - 1.6e-34 119.6 0.1 1.9e-34 119.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 RKO95037.1 - 1.1e-30 105.8 0.1 2.1e-30 105.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Rubredoxin_2 PF18073.1 RKO95037.1 - 1.9 8.3 8.8 4.6 7.1 8.8 1.6 1 1 0 1 1 1 0 Rubredoxin metal binding domain Pkinase PF00069.25 RKO95038.1 - 6.8e-09 35.5 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RKO95038.1 - 0.022 14.1 0.0 0.027 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.17 RKO95038.1 - 0.062 12.6 0.0 0.12 11.6 0.0 1.4 2 0 0 2 2 2 0 Protein tyrosine kinase Ribosomal_L30_N PF08079.12 RKO95039.1 - 5.3e-22 77.8 15.3 6.8e-22 77.5 15.3 1.1 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Rep_Org_C PF06926.11 RKO95039.1 - 0.13 12.6 1.2 0.15 12.4 1.2 1.2 1 0 0 1 1 1 0 Putative replisome organiser protein C-terminus Branch PF02485.21 RKO95040.1 - 2e-17 63.5 0.1 3.7e-17 62.6 0.1 1.4 1 1 0 1 1 1 1 Core-2/I-Branching enzyme G-alpha PF00503.20 RKO95041.1 - 1e-23 84.1 0.0 1.1e-23 84.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RKO95041.1 - 0.0031 17.0 0.1 0.0042 16.6 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.6 RKO95041.1 - 0.01 15.6 0.2 0.021 14.6 0.2 1.5 1 1 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RKO95041.1 - 0.029 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family MCM PF00493.23 RKO95041.1 - 0.039 13.0 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_15 PF13175.6 RKO95041.1 - 0.071 12.8 0.0 0.075 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Fes1 PF08609.10 RKO95041.1 - 0.076 13.9 0.2 0.099 13.5 0.2 1.2 1 0 0 1 1 1 0 Nucleotide exchange factor Fes1 AAA_24 PF13479.6 RKO95041.1 - 0.14 11.8 0.1 0.4 10.4 0.1 1.6 1 1 1 2 2 2 0 AAA domain TAF6_C PF07571.13 RKO95043.1 - 1e-21 77.0 0.0 2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 RKO95043.1 - 0.00076 19.9 0.6 0.013 16.0 0.1 2.6 2 1 1 3 3 3 1 HEAT-like repeat HEAT_EZ PF13513.6 RKO95044.1 - 0.00023 21.6 0.7 0.62 10.6 0.2 2.8 2 1 1 3 3 3 2 HEAT-like repeat Choline_transpo PF04515.12 RKO95045.1 - 1.5e-07 30.9 2.4 1.7e-07 30.7 2.4 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter OxoGdeHyase_C PF16870.5 RKO95047.1 - 3.7e-39 133.8 0.1 4.2e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal tRNA_bind PF01588.20 RKO95048.1 - 3e-11 43.3 0.0 4.2e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Putative tRNA binding domain AICARFT_IMPCHas PF01808.18 RKO95049.1 - 1.1e-16 61.2 0.5 1.3e-16 60.9 0.5 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 RKO95049.1 - 0.0058 16.8 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain DUF846 PF05832.12 RKO95051.1 - 4.8e-39 133.6 6.2 5.7e-39 133.3 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Na_H_Exchanger PF00999.21 RKO95051.1 - 0.011 14.6 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family DcuC PF03606.15 RKO95051.1 - 0.024 13.1 0.0 0.026 13.0 0.0 1.0 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier UCH PF00443.29 RKO95055.1 - 1.8e-07 31.0 0.0 1.8e-07 30.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKO95055.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase C1_2 PF03107.16 RKO95055.1 - 0.15 12.4 0.4 0.26 11.6 0.4 1.4 1 0 0 1 1 1 0 C1 domain Hydantoinase_B PF02538.14 RKO95056.1 - 1.3e-47 162.4 0.0 1.4e-47 162.3 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase RIC1 PF07064.13 RKO95058.1 - 1.5e-25 90.1 0.2 1.7e-25 89.9 0.2 1.0 1 0 0 1 1 1 1 RIC1 DUF5092 PF17010.5 RKO95059.1 - 7.8e-18 64.9 0.0 8.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5092) Glyco_hydro_71 PF03659.14 RKO95060.1 - 4.1e-18 65.4 0.3 4.7e-18 65.2 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Pkinase PF00069.25 RKO95061.1 - 6.2e-19 68.4 0.0 7.2e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95061.1 - 1.3e-07 31.2 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4116 PF13475.6 RKO95061.1 - 0.17 11.6 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) IF-2B PF01008.17 RKO95063.1 - 9e-15 54.6 0.0 9.9e-15 54.5 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DMRL_synthase PF00885.19 RKO95064.1 - 1.7e-27 96.0 0.0 1.8e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase PCNA_N PF00705.18 RKO95065.1 - 1.3e-53 180.0 4.1 1.5e-53 179.8 4.1 1.0 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Hus1 PF04005.12 RKO95065.1 - 0.0032 16.6 0.1 0.0035 16.5 0.1 1.1 1 0 0 1 1 1 1 Hus1-like protein Rad9 PF04139.13 RKO95065.1 - 0.005 16.3 0.0 0.0053 16.2 0.0 1.0 1 0 0 1 1 1 1 Rad9 zf-rbx1 PF12678.7 RKO95066.1 - 1.5e-25 89.2 12.7 1.8e-25 88.9 12.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 RKO95066.1 - 1.9e-16 59.9 10.5 2.3e-16 59.6 10.5 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 RKO95066.1 - 1.4e-07 31.8 13.5 7e-06 26.3 13.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RKO95066.1 - 9.8e-05 22.1 11.8 0.0016 18.3 11.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKO95066.1 - 0.00014 21.6 14.4 0.0015 18.3 9.2 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SCIFF PF13165.6 RKO95066.1 - 0.027 14.4 2.8 0.043 13.8 2.8 1.4 1 0 0 1 1 1 0 Six-cysteine peptide SCIFF zf-RING_11 PF17123.5 RKO95066.1 - 0.051 13.3 15.5 6.1 6.7 15.5 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 RKO95066.1 - 0.055 13.3 10.9 0.3 11.0 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO95066.1 - 0.092 12.8 9.4 0.68 10.0 9.4 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 RKO95066.1 - 0.29 11.3 9.1 0.46 10.7 0.8 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 RKO95066.1 - 0.38 10.4 14.2 1.6 8.4 9.8 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 RKO95066.1 - 0.39 10.9 9.6 3.2 8.0 9.8 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_5 PF14634.6 RKO95066.1 - 1.7 8.7 11.7 21 5.2 11.7 2.4 1 1 1 2 2 2 0 zinc-RING finger domain MLVIN_C PF18697.1 RKO95067.1 - 0.011 15.8 1.5 0.012 15.7 0.2 1.7 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Sec1 PF00995.23 RKO95068.1 - 1.2e-32 113.9 0.1 1.3e-32 113.8 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Dehydratase_SU PF02287.15 RKO95068.1 - 0.18 11.9 1.4 6.1 6.9 0.1 2.2 1 1 0 2 2 2 0 Dehydratase small subunit ACBP PF00887.19 RKO95070.1 - 1.9e-26 92.1 0.1 2.2e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Prefoldin_2 PF01920.20 RKO95071.1 - 2.5e-10 40.3 0.2 2.7e-10 40.1 0.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit KfrA_N PF11740.8 RKO95071.1 - 0.00075 20.2 3.4 0.0008 20.1 3.4 1.2 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term Metal_resist PF13801.6 RKO95071.1 - 0.012 15.8 1.3 0.013 15.7 1.3 1.1 1 0 0 1 1 1 0 Heavy-metal resistance PEP-utilisers_N PF05524.13 RKO95071.1 - 0.02 15.1 0.6 0.025 14.7 0.6 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal HBS1_N PF08938.10 RKO95071.1 - 0.025 14.9 0.9 0.03 14.6 0.9 1.2 1 0 0 1 1 1 0 HBS1 N-terminus DivIC PF04977.15 RKO95071.1 - 0.067 13.0 1.1 0.11 12.3 1.1 1.3 1 0 0 1 1 1 0 Septum formation initiator AAA_lid_11 PF18198.1 RKO95072.1 - 5.5e-40 136.9 0.3 5.9e-40 136.8 0.3 1.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain DUF956 PF06115.11 RKO95072.1 - 0.054 13.2 0.0 0.085 12.6 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF956) DNA_pol_B_exo1 PF03104.19 RKO95074.1 - 4.9e-07 29.2 0.0 5.6e-07 29.0 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Aldedh PF00171.22 RKO95075.1 - 7.7e-11 41.2 0.1 8.5e-11 41.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family efThoc1 PF11957.8 RKO95076.1 - 3.2e-20 72.3 0.0 3.4e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Ribosomal_S5_C PF03719.15 RKO95077.1 - 1.7e-21 75.5 0.1 2.2e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 RKO95077.1 - 0.079 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain DUF3487 PF11990.8 RKO95078.1 - 3.3 7.6 0.0 3.3 7.6 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) cNMP_binding PF00027.29 RKO95079.1 - 1.9e-21 75.9 0.0 2.8e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Helicase_C PF00271.31 RKO95081.1 - 3.8e-09 36.9 0.0 8.8e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RKO95081.1 - 0.00055 19.2 0.0 0.00076 18.7 0.0 1.2 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 IDO PF01231.18 RKO95082.1 - 2.9e-38 131.8 0.1 3.2e-38 131.6 0.1 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase THF_DHG_CYH_C PF02882.19 RKO95083.1 - 8e-67 223.5 1.2 8.9e-67 223.4 1.2 1.0 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain OCD_Mu_crystall PF02423.15 RKO95083.1 - 0.0042 16.1 0.1 0.0054 15.7 0.1 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family AlaDh_PNT_C PF01262.21 RKO95083.1 - 0.0075 15.6 0.2 0.0099 15.2 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 RKO95083.1 - 0.046 13.8 0.0 0.55 10.3 0.0 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 RKO95083.1 - 0.073 13.1 0.3 4.2 7.4 0.3 2.2 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain eIF-6 PF01912.18 RKO95084.1 - 4.2e-72 241.7 0.1 4.7e-72 241.5 0.1 1.0 1 0 0 1 1 1 1 eIF-6 family Myosin_head PF00063.21 RKO95086.1 - 5.4e-35 120.8 0.1 6e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) ATP_sub_h PF10775.9 RKO95088.1 - 6.5e-10 38.9 1.0 1e-09 38.2 1.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h HOIP-UBA PF16678.5 RKO95089.1 - 0.0073 16.3 0.2 1 9.4 0.1 2.0 1 1 1 2 2 2 2 HOIP UBA domain pair UBA PF00627.31 RKO95089.1 - 0.021 14.7 1.1 0.028 14.3 0.2 1.7 2 0 0 2 2 2 0 UBA/TS-N domain TFIID-18kDa PF02269.16 RKO95091.1 - 0.00047 20.1 0.1 0.00087 19.3 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Guanylate_kin PF00625.21 RKO95092.1 - 7.4e-37 126.8 0.0 8.2e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.6 RKO95092.1 - 2.2e-07 31.1 0.0 5.1e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKO95092.1 - 5.4e-06 26.7 0.0 5.4e-06 26.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKO95092.1 - 6.9e-05 23.3 0.0 8e-05 23.1 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 RKO95092.1 - 0.0001 22.4 0.0 0.00013 22.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 RKO95092.1 - 0.00027 21.5 0.0 0.00027 21.5 0.0 1.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 RKO95092.1 - 0.00037 21.0 0.0 0.00037 21.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 RKO95092.1 - 0.00057 20.2 0.0 0.00076 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 RKO95092.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RKO95092.1 - 0.0017 18.3 0.0 0.0021 18.0 0.0 1.3 1 1 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 RKO95092.1 - 0.0024 17.8 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_28 PF13521.6 RKO95092.1 - 0.0033 17.7 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 RKO95092.1 - 0.0043 17.0 0.0 0.0043 17.0 0.0 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea Pox_A32 PF04665.12 RKO95092.1 - 0.0054 16.2 0.0 0.0058 16.1 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein KTI12 PF08433.10 RKO95092.1 - 0.0077 15.7 0.0 0.0096 15.4 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Rad17 PF03215.15 RKO95092.1 - 0.0081 16.1 0.0 0.0083 16.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 RKO95092.1 - 0.0087 16.6 0.0 0.014 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 RKO95092.1 - 0.0092 15.8 0.0 0.0092 15.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 RKO95092.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 RKO95092.1 - 0.015 14.9 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 RKO95092.1 - 0.017 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 RKO95092.1 - 0.021 14.9 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 RKO95092.1 - 0.023 14.6 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 RKO95092.1 - 0.023 14.9 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 RKO95092.1 - 0.029 14.3 0.0 0.03 14.2 0.0 1.3 1 1 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 RKO95092.1 - 0.03 14.1 0.0 0.034 13.9 0.0 1.2 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PRK PF00485.18 RKO95092.1 - 0.037 13.8 0.0 0.085 12.6 0.0 1.6 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 RKO95092.1 - 0.041 13.1 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Septin PF00735.18 RKO95092.1 - 0.046 13.0 0.0 0.051 12.9 0.0 1.1 1 0 0 1 1 1 0 Septin T2SSE PF00437.20 RKO95092.1 - 0.051 12.6 0.0 0.073 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 RKO95092.1 - 0.053 13.2 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 RKO95092.1 - 0.07 13.1 0.0 0.08 12.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RKO95092.1 - 0.076 12.7 0.0 0.2 11.3 0.0 1.6 1 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 RKO95092.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRPRB PF09439.10 RKO95092.1 - 0.09 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 RKO95092.1 - 0.12 11.8 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 RKO95092.1 - 0.12 12.4 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_17 PF13207.6 RKO95092.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 RKO95092.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase Adeno_IVa2 PF02456.15 RKO95092.1 - 0.19 10.5 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Adenovirus IVa2 protein KAP_NTPase PF07693.14 RKO95092.1 - 0.19 10.9 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain G-alpha PF00503.20 RKO95092.1 - 0.24 10.5 0.0 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit SURF4 PF02077.15 RKO95093.1 - 2.2e-53 181.6 2.0 2.5e-53 181.4 2.0 1.0 1 0 0 1 1 1 1 SURF4 family SIR2 PF02146.17 RKO95094.1 - 1.3e-37 129.4 0.0 1.6e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Cofilin_ADF PF00241.20 RKO95095.1 - 6.7e-15 55.0 0.2 7.4e-15 54.8 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FliM PF02154.15 RKO95095.1 - 0.075 12.9 0.0 0.079 12.8 0.0 1.1 1 0 0 1 1 1 0 Flagellar motor switch protein FliM BUD22 PF09073.10 RKO95096.1 - 0.11 11.9 9.5 0.15 11.4 9.5 1.2 1 0 0 1 1 1 0 BUD22 NUC194 PF08163.12 RKO95096.1 - 0.12 11.3 1.8 0.088 11.7 0.5 1.4 2 0 0 2 2 2 0 NUC194 domain FAM176 PF14851.6 RKO95096.1 - 0.79 9.4 11.3 11 5.6 0.1 2.3 2 0 0 2 2 2 0 FAM176 family GOLD_2 PF13897.6 RKO95096.1 - 3.7 8.0 5.3 30 5.1 0.0 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Pkinase PF00069.25 RKO95097.1 - 9.7e-23 80.9 0.1 1e-22 80.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95097.1 - 9.3e-17 61.2 0.1 1e-16 61.1 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase MRC1 PF09444.10 RKO95098.1 - 9.1e-21 74.9 11.1 1.1e-20 74.6 11.1 1.1 1 0 0 1 1 1 1 MRC1-like domain DUF2009 PF09418.10 RKO95099.1 - 2.3e-51 175.3 0.2 2.6e-51 175.2 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) tRNA_m1G_MT PF01746.21 RKO95100.1 - 5.8e-18 65.3 0.0 6.9e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF99 PF01949.16 RKO95100.1 - 0.021 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF99 RVT_1 PF00078.27 RKO95101.1 - 2e-06 27.5 0.0 2.5e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MSP1_C PF07462.11 RKO95102.1 - 0.06 12.0 3.7 0.072 11.8 3.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus BUD22 PF09073.10 RKO95102.1 - 0.53 9.6 14.6 0.61 9.4 14.6 1.0 1 0 0 1 1 1 0 BUD22 LRR_8 PF13855.6 RKO95103.1 - 4.1e-14 52.1 2.7 3.6e-08 33.0 1.6 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RKO95103.1 - 3.5e-12 46.3 1.7 2e-07 31.2 0.0 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKO95103.1 - 0.0094 16.4 2.8 16 6.5 0.4 3.4 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 RKO95103.1 - 0.017 15.2 5.9 0.28 11.3 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat Cluap1 PF10234.9 RKO95104.1 - 7.1e-08 32.2 0.5 7.1e-08 32.2 0.5 1.5 2 0 0 2 2 2 1 Clusterin-associated protein-1 TFIIA PF03153.13 RKO95104.1 - 0.013 15.5 12.9 0.016 15.3 12.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.10 RKO95104.1 - 0.048 13.0 10.6 0.056 12.8 10.6 1.0 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 RKO95104.1 - 1.2 8.4 16.7 1.5 8.1 16.7 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-Q PF13094.6 RKO95104.1 - 3 8.0 7.8 4.9 7.3 7.8 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Hydrophobin PF01185.18 RKO95105.1 - 1.1e-10 42.0 10.3 1.4e-10 41.7 10.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Citrate_synt PF00285.21 RKO95106.1 - 0.044 12.8 0.0 0.083 11.9 0.0 1.4 2 0 0 2 2 2 0 Citrate synthase, C-terminal domain COE1_HLH PF16423.5 RKO95106.1 - 0.21 11.3 1.4 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Transcription factor COE1 helix-loop-helix domain Med6 PF04934.14 RKO95107.1 - 1.3e-30 105.9 0.0 1.4e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 MED6 mediator sub complex component Methyltransf_23 PF13489.6 RKO95109.1 - 1.4e-17 64.0 0.0 1.9e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO95109.1 - 2.7e-10 40.8 0.0 4.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RKO95109.1 - 5.9e-10 38.9 0.0 7.7e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 RKO95109.1 - 2.8e-09 36.9 0.0 3.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO95109.1 - 1.2e-08 35.5 0.0 2.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO95109.1 - 0.00021 22.0 0.0 0.00033 21.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TAFII28 PF04719.14 RKO95110.1 - 3.7e-28 97.4 0.0 4.7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 RKO95110.1 - 0.00058 20.1 0.0 0.001 19.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ArgoN PF16486.5 RKO95111.1 - 4.3e-08 33.9 0.0 5.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain of argonaute RRN3 PF05327.11 RKO95111.1 - 0.12 10.9 0.0 0.47 8.9 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 tRNA_anti-codon PF01336.25 RKO95113.1 - 4.9e-07 29.6 0.0 6.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rep_fac-A_C PF08646.10 RKO95113.1 - 0.049 13.4 0.0 0.064 13.0 0.0 1.3 1 1 0 1 1 1 0 Replication factor-A C terminal domain RRM_1 PF00076.22 RKO95114.1 - 1.6e-19 69.5 0.2 1.8e-19 69.3 0.2 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO95114.1 - 0.00057 20.0 0.0 0.004 17.2 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif NTP_transferase PF00483.23 RKO95114.1 - 0.015 14.9 0.0 0.015 14.9 0.0 1.0 1 0 0 1 1 1 0 Nucleotidyl transferase XS PF03468.14 RKO95114.1 - 0.12 12.6 0.1 0.15 12.4 0.1 1.0 1 0 0 1 1 1 0 XS domain RNA_pol_Rpb2_6 PF00562.28 RKO95115.1 - 1.3e-42 146.3 0.5 1.4e-42 146.2 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 DZF PF07528.14 RKO95115.1 - 0.079 12.6 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 DZF domain DHHC PF01529.20 RKO95116.1 - 9.3e-39 132.6 0.1 1.1e-38 132.4 0.1 1.0 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF1272 PF06906.11 RKO95116.1 - 0.76 9.9 6.2 2.2 8.5 6.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Adaptin_N PF01602.20 RKO95117.1 - 4.4e-37 127.8 0.0 5e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 RKO95117.1 - 1.1e-08 35.4 0.0 0.00026 21.3 0.0 2.6 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 RKO95117.1 - 0.0078 16.4 0.1 1.8 9.0 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat DUF3385 PF11865.8 RKO95117.1 - 0.05 13.5 0.0 0.25 11.3 0.0 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF3385) INTS5_N PF14837.6 RKO95117.1 - 0.11 12.0 0.0 1.6 8.3 0.0 2.2 1 1 0 2 2 2 0 Integrator complex subunit 5 N-terminus HEAT_EZ PF13513.6 RKO95117.1 - 0.14 12.7 0.0 3.9 8.1 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat WD40 PF00400.32 RKO95118.1 - 9.8e-10 38.9 0.8 5.2e-05 23.9 0.5 2.5 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95118.1 - 0.00021 21.5 0.0 0.00032 20.9 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain AF-4 PF05110.13 RKO95120.1 - 0.22 9.6 5.9 0.18 9.9 5.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Rab5ip PF07019.12 RKO95121.1 - 4.1e-15 56.1 3.8 5.1e-15 55.8 3.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Ribosomal_L22 PF00237.19 RKO95123.1 - 6.1e-26 90.7 0.1 6.1e-26 90.7 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Cyt-b5 PF00173.28 RKO95124.1 - 6.9e-10 38.9 0.0 8.3e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain tRNA-synt_1c PF00749.21 RKO95125.1 - 5.5e-59 199.6 0.0 6e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Clat_adaptor_s PF01217.20 RKO95126.1 - 4.6e-27 94.7 1.1 5.6e-27 94.4 1.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MLVIN_C PF18697.1 RKO95127.1 - 0.0026 17.8 0.0 0.0046 17.0 0.0 1.4 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Thioredox_DsbH PF03190.15 RKO95128.1 - 4.8e-73 244.5 0.0 6.1e-73 244.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 RKO95128.1 - 4.9e-10 39.5 0.0 8.3e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RKO95128.1 - 0.0023 18.4 0.0 0.0044 17.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain AAA_12 PF13087.6 RKO95130.1 - 2e-12 47.2 0.0 2.1e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 AAA domain tRNA-synt_1d PF00750.19 RKO95131.1 - 4.1e-29 101.6 1.0 4.3e-29 101.6 1.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (R) Ntox1 PF15500.6 RKO95131.1 - 0.1 13.0 1.0 0.18 12.2 1.0 1.3 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 GMP_synt_C PF00958.22 RKO95132.1 - 6.6e-29 99.8 0.1 7.2e-29 99.7 0.1 1.0 1 0 0 1 1 1 1 GMP synthase C terminal domain RRM_1 PF00076.22 RKO95134.1 - 3.4e-13 49.2 0.2 6.2e-07 29.1 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKO95134.1 - 6.6e-05 22.7 0.0 0.0092 15.8 0.0 2.1 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 RKO95134.1 - 0.00054 20.0 0.1 0.089 12.9 0.0 3.0 2 2 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 RKO95134.1 - 0.014 15.4 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PTH2 PF01981.16 RKO95135.1 - 4e-15 56.1 0.0 4.5e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 GalKase_gal_bdg PF10509.9 RKO95135.1 - 0.078 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Dus PF01207.17 RKO95136.1 - 6.1e-19 68.2 0.0 6.6e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) AICARFT_IMPCHas PF01808.18 RKO95137.1 - 4.2e-19 69.1 0.2 5.8e-19 68.6 0.2 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme Mannosyl_trans3 PF11051.8 RKO95138.1 - 2e-36 125.8 0.1 1.2e-35 123.2 0.1 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative RNA_pol_Rpb1_5 PF04998.17 RKO95139.1 - 8.2e-29 100.9 0.0 8.5e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RabGAP-TBC PF00566.18 RKO95140.1 - 0.00011 22.0 0.3 0.00017 21.3 0.3 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RhoGAP PF00620.27 RKO95141.1 - 5.1e-15 55.6 0.0 6.2e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF4710 PF15828.5 RKO95144.1 - 0.29 11.3 2.2 0.5 10.5 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) Casc1_N PF15927.5 RKO95144.1 - 0.31 10.7 12.7 0.47 10.1 12.7 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Ureide_permease PF07168.11 RKO95144.1 - 0.33 9.7 0.3 0.44 9.2 0.3 1.1 1 0 0 1 1 1 0 Ureide permease Acyl-CoA_dh_1 PF00441.24 RKO95145.1 - 2.2e-40 138.3 2.8 2.5e-40 138.1 2.8 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 RKO95145.1 - 4.2e-16 59.4 0.4 4.9e-16 59.2 0.4 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PAH PF02671.21 RKO95147.1 - 1.7e-13 50.4 0.0 2.4e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Paired amphipathic helix repeat BAF1_ABF1 PF04684.13 RKO95149.1 - 1.2 8.2 10.6 1.4 7.9 10.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribosomal_S5 PF00333.20 RKO95150.1 - 5e-14 52.0 1.0 8.8e-14 51.2 1.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Aconitase PF00330.20 RKO95151.1 - 1.7e-51 175.6 0.0 1.9e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) WD40 PF00400.32 RKO95152.1 - 4.5e-09 36.8 2.0 2.1e-06 28.3 0.3 2.1 2 0 0 2 2 2 2 WD domain, G-beta repeat UTP25 PF06862.12 RKO95153.1 - 8e-43 146.9 0.0 8.8e-43 146.8 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 GLTP PF08718.11 RKO95153.1 - 0.1 12.9 0.2 0.21 11.9 0.2 1.4 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) Sin3a_C PF16879.5 RKO95154.1 - 1.2e-14 54.7 0.0 2.1e-14 54.0 0.0 1.4 2 0 0 2 2 2 1 C-terminal domain of Sin3a protein DNA_pol_phi PF04931.13 RKO95155.1 - 1.1e-11 43.6 0.0 1.3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase phi KfrA_N PF11740.8 RKO95155.1 - 0.03 15.0 0.5 0.063 14.0 0.5 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term HEAT PF02985.22 RKO95155.1 - 0.06 13.6 0.1 2.2 8.8 0.0 2.8 2 0 0 2 2 2 0 HEAT repeat tRNA-synt_2 PF00152.20 RKO95156.1 - 0.003 16.7 0.5 0.004 16.3 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RKO95156.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MMR_HSR1 PF01926.23 RKO95157.1 - 1.3e-14 54.3 0.4 3.2e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKO95157.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RKO95157.1 - 5.7e-05 23.1 0.0 0.00014 21.8 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 RKO95157.1 - 0.008 16.2 0.5 0.055 13.5 0.0 2.2 2 0 0 2 2 2 1 Dynamin family BUD22 PF09073.10 RKO95157.1 - 0.085 12.2 10.2 0.098 12.0 10.2 1.1 1 0 0 1 1 1 0 BUD22 AIG1 PF04548.16 RKO95157.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_15 PF13175.6 RKO95157.1 - 0.15 11.8 0.5 7.7 6.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF2681 PF10883.8 RKO95157.1 - 0.25 11.8 4.5 0.24 11.8 3.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) SDA1 PF05285.12 RKO95157.1 - 0.25 10.7 12.8 0.31 10.4 12.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 RKO95157.1 - 0.6 8.3 12.1 0.61 8.2 12.1 1.0 1 0 0 1 1 1 0 Nop14-like family AAA_16 PF13191.6 RKO95157.1 - 1.4 9.3 5.2 1.5 9.2 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain PGA2 PF07543.12 RKO95157.1 - 2.7 8.0 9.6 4.7 7.2 9.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF4407 PF14362.6 RKO95157.1 - 2.8 7.2 6.4 3.8 6.8 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CDC45 PF02724.14 RKO95157.1 - 2.8 6.1 13.8 3.8 5.7 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Vfa1 PF08432.10 RKO95157.1 - 3.1 8.1 10.6 4.7 7.5 10.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Presenilin PF01080.17 RKO95157.1 - 4.3 6.0 5.1 5.2 5.7 5.1 1.1 1 0 0 1 1 1 0 Presenilin DNA_pol_phi PF04931.13 RKO95157.1 - 5.9 4.9 14.2 6.6 4.7 14.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 RKO95157.1 - 6.2 6.3 11.1 7.8 6.0 11.1 1.2 1 0 0 1 1 1 0 PPP4R2 Ribosomal_L34e PF01199.18 RKO95158.1 - 1.1e-24 86.5 0.5 1.2e-24 86.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L34e Glycos_transf_1 PF00534.20 RKO95159.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Choline_transpo PF04515.12 RKO95160.1 - 4.3e-08 32.7 1.3 4.9e-08 32.5 1.3 1.1 1 0 0 1 1 1 1 Plasma-membrane choline transporter DEAD PF00270.29 RKO95161.1 - 6.1e-08 32.6 0.0 1.4e-07 31.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C2H2_assoc3 PF16637.5 RKO95163.1 - 0.036 14.3 1.1 0.074 13.3 1.1 1.5 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz TPR_1 PF00515.28 RKO95164.1 - 4.6e-08 32.5 0.1 0.0025 17.6 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKO95164.1 - 5.1e-08 32.4 0.1 0.004 17.1 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKO95164.1 - 0.0028 17.3 0.1 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 RKO95164.1 - 0.0031 17.8 0.7 0.018 15.3 0.7 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 RKO95164.1 - 0.068 13.8 0.4 0.11 13.2 0.4 1.6 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 RKO95164.1 - 0.14 12.4 0.0 28 5.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat UBA PF00627.31 RKO95165.1 - 1.6e-14 53.5 0.3 6.1e-14 51.6 0.5 1.7 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.6 RKO95165.1 - 0.025 14.4 0.1 0.066 13.0 0.0 1.7 1 1 1 2 2 2 0 UBA-like domain Acyl-CoA_ox_N PF14749.6 RKO95166.1 - 8.8e-10 39.2 0.1 1.2e-09 38.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 RKO95166.1 - 4.6e-07 29.9 0.0 6.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain CLP_protease PF00574.23 RKO95168.1 - 9.3e-18 64.7 0.0 1e-17 64.6 0.0 1.0 1 0 0 1 1 1 1 Clp protease Plectin PF00681.20 RKO95168.1 - 0.15 11.9 0.0 0.49 10.3 0.0 1.7 1 1 1 2 2 2 0 Plectin repeat zf-Sec23_Sec24 PF04810.15 RKO95169.1 - 3.9e-14 52.4 3.3 7.4e-14 51.5 3.3 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Cwf_Cwc_15 PF04889.12 RKO95170.1 - 8.5 6.0 17.0 11 5.6 17.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Myosin_head PF00063.21 RKO95171.1 - 2.5e-10 39.2 0.0 4.1e-10 38.5 0.0 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Pho88 PF10032.9 RKO95172.1 - 4.2e-43 146.7 0.0 4.6e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Pkinase PF00069.25 RKO95173.1 - 2.9e-29 102.3 0.0 3.4e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95173.1 - 5.2e-16 58.7 0.0 6e-16 58.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RKO95173.1 - 0.0013 17.8 0.1 0.0014 17.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKO95173.1 - 0.0084 15.5 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 RKO95173.1 - 0.063 12.2 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CHCH PF06747.13 RKO95174.1 - 3.7e-07 30.1 5.7 5.9e-07 29.5 5.7 1.4 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 RKO95174.1 - 0.0081 16.2 3.3 0.041 13.9 0.6 2.1 1 1 2 3 3 3 2 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 RKO95174.1 - 0.014 15.4 0.4 0.97 9.5 0.1 2.1 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, tRNA-synt_His PF13393.6 RKO95175.1 - 0.00089 18.6 2.4 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase LprI PF07007.12 RKO95175.1 - 1.2 9.9 8.2 1.5 9.5 7.7 1.3 1 1 0 1 1 1 0 Lysozyme inhibitor LprI DUF883 PF05957.13 RKO95175.1 - 1.8 9.2 11.9 4.4 8.0 11.9 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) RF-1 PF00472.20 RKO95177.1 - 1e-22 80.2 0.5 1.2e-22 80.0 0.5 1.0 1 0 0 1 1 1 1 RF-1 domain HSP70 PF00012.20 RKO95178.1 - 0.00027 19.3 0.0 0.00033 19.0 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein RVP_2 PF08284.11 RKO95179.1 - 0.037 13.8 0.1 0.037 13.8 0.1 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease 3HCDH PF00725.22 RKO95180.1 - 3.5e-34 117.3 0.0 5e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 RKO95180.1 - 7.3e-13 48.8 0.1 9.4e-13 48.4 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DHC_N2 PF08393.13 RKO95181.1 - 2.8e-26 92.6 0.0 3.3e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Glyco_hydro_16 PF00722.21 RKO95181.1 - 5.4e-13 48.8 0.4 8.5e-13 48.1 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Aldo_ket_red PF00248.21 RKO95185.1 - 2.8e-24 85.9 0.0 3e-24 85.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Kinesin PF00225.23 RKO95186.1 - 3.1e-59 200.6 0.1 3.4e-59 200.4 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain AraC_N PF06719.13 RKO95186.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus Cwf_Cwc_15 PF04889.12 RKO95187.1 - 0.076 12.7 14.1 0.092 12.5 14.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Tim54 PF11711.8 RKO95187.1 - 0.23 10.2 7.5 0.56 8.9 7.5 1.7 1 1 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SURF2 PF05477.11 RKO95187.1 - 0.68 9.6 5.8 0.82 9.3 5.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) F-protein PF00469.20 RKO95187.1 - 1.8 8.1 4.8 3.5 7.1 4.5 1.7 1 1 0 1 1 1 0 Negative factor, (F-Protein) or Nef RRN3 PF05327.11 RKO95187.1 - 2.3 6.6 9.6 2.8 6.4 9.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3246 PF11596.8 RKO95187.1 - 2.6 7.4 9.1 3.7 6.9 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) PI3K_1B_p101 PF10486.9 RKO95187.1 - 3.1 5.5 5.9 3.6 5.3 5.9 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit D123 PF07065.14 RKO95187.1 - 8.2 5.5 8.5 38 3.3 8.5 1.9 1 1 0 1 1 1 0 D123 Nop14 PF04147.12 RKO95187.1 - 9.4 4.3 18.9 11 4.1 18.9 1.0 1 0 0 1 1 1 0 Nop14-like family Mito_carr PF00153.27 RKO95188.1 - 2e-43 146.2 0.0 5.9e-27 93.4 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein DRIM PF07539.12 RKO95191.1 - 0.073 11.4 0.2 0.14 10.4 0.1 1.6 1 1 0 1 1 1 0 Down-regulated in metastasis CRISPR_Cse2 PF09485.10 RKO95191.1 - 0.079 13.5 0.2 0.75 10.3 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) P21-Arc PF04062.14 RKO95192.1 - 7.2e-34 117.3 0.0 7.9e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit RIO1 PF01163.22 RKO95195.1 - 7.9e-46 156.0 0.0 1e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 RKO95195.1 - 6.1e-09 36.2 1.5 0.00035 20.6 0.8 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 RKO95195.1 - 1.6e-07 30.9 0.1 0.0035 16.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 RKO95195.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Amelogenin PF02948.15 RKO95196.1 - 0.009 16.7 1.8 0.0095 16.6 1.8 1.2 1 0 0 1 1 1 1 Amelogenin RCC1_2 PF13540.6 RKO95197.1 - 0.0029 17.3 4.3 0.019 14.8 0.1 2.6 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Evr1_Alr PF04777.13 RKO95198.1 - 4.9e-25 87.9 0.2 5.6e-25 87.7 0.2 1.0 1 0 0 1 1 1 1 Erv1 / Alr family SNAD4 PF18750.1 RKO95198.1 - 0.047 13.8 0.1 0.055 13.6 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC1 PF18769.1 RKO95198.1 - 0.087 13.1 0.2 0.22 11.8 0.0 1.7 1 1 1 2 2 2 0 APOBEC1 Acyl-CoA_dh_1 PF00441.24 RKO95199.1 - 1.8e-28 99.6 0.6 2.2e-28 99.3 0.6 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 RKO95199.1 - 5e-07 30.1 0.9 1.2e-06 28.8 0.9 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Mannosyl_trans PF05007.13 RKO95200.1 - 9.2e-17 61.8 6.6 1.1e-16 61.5 6.6 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) Synaptobrevin PF00957.21 RKO95200.1 - 0.18 11.6 0.5 0.27 11.1 0.5 1.2 1 0 0 1 1 1 0 Synaptobrevin Not1 PF04054.15 RKO95201.1 - 3.4e-50 171.0 0.0 4e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 Ribosomal_L1 PF00687.21 RKO95203.1 - 1.2e-05 25.2 0.0 2.4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family P-II PF00543.22 RKO95203.1 - 0.074 13.7 0.3 0.43 11.2 0.1 2.1 1 1 1 2 2 2 0 Nitrogen regulatory protein P-II MIP PF00230.20 RKO95204.1 - 2.4e-27 96.1 7.6 2.8e-27 95.9 7.6 1.0 1 0 0 1 1 1 1 Major intrinsic protein 60KD_IMP PF02096.20 RKO95205.1 - 3.2e-27 95.4 0.2 3.7e-27 95.3 0.2 1.0 1 0 0 1 1 1 1 60Kd inner membrane protein XRN1_D2_D3 PF18334.1 RKO95206.1 - 2.8e-06 27.5 0.2 6.6e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain Xrn1_D3 PF18194.1 RKO95206.1 - 0.0077 16.3 0.6 0.022 14.9 0.1 1.8 2 0 0 2 2 2 1 Exoribonuclease 1 Domain-3 Mei5 PF10376.9 RKO95206.1 - 0.067 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Double-strand recombination repair protein CC2-LZ PF16516.5 RKO95206.1 - 0.098 13.0 0.4 0.16 12.3 0.4 1.3 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator TolB_like PF15869.5 RKO95206.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 TolB-like 6-blade propeller-like PAS PF00989.25 RKO95207.1 - 8.3e-05 22.6 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 RKO95207.1 - 0.022 14.8 0.0 0.039 14.0 0.0 1.6 1 1 0 1 1 1 0 PAS domain MLTR_LBD PF17765.1 RKO95207.1 - 0.027 14.6 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain RPEL PF02755.15 RKO95208.1 - 7.2e-11 41.4 6.4 4.2e-05 23.1 0.1 3.5 3 0 0 3 3 3 2 RPEL repeat P16-Arc PF04699.14 RKO95208.1 - 0.001 19.6 0.3 0.0046 17.5 0.2 1.9 1 1 1 2 2 2 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UQ_con PF00179.26 RKO95209.1 - 3.3e-23 81.9 0.0 3.7e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RKO95209.1 - 0.0034 17.7 0.0 0.004 17.4 0.0 1.2 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 RKO95209.1 - 0.012 15.4 0.1 0.012 15.3 0.1 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 RKO95209.1 - 0.023 14.3 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Peptidase_M28 PF04389.17 RKO95210.1 - 7.8e-15 55.1 0.0 1.2e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 RKO95210.1 - 5.9e-07 29.4 0.0 9.9e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ParA PF10609.9 RKO95212.1 - 1.1e-30 106.9 0.0 1.2e-30 106.8 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase TAL_FSA PF00923.19 RKO95213.1 - 8.3e-84 281.3 0.0 9.2e-84 281.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase Ribosomal_S17e PF00833.18 RKO95214.1 - 2.9e-34 117.6 0.9 3.2e-34 117.5 0.9 1.0 1 0 0 1 1 1 1 Ribosomal S17 IpaB_EvcA PF03278.13 RKO95214.1 - 0.042 13.6 0.0 0.043 13.5 0.0 1.0 1 0 0 1 1 1 0 IpaB/EvcA family Ribosomal_L37e PF01907.19 RKO95214.1 - 0.072 13.3 0.0 0.099 12.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L37e DUF3016 PF11454.8 RKO95214.1 - 0.13 12.0 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) UPF0254 PF06787.11 RKO95215.1 - 0.095 12.5 0.0 0.22 11.3 0.0 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0254) GTP_EFTU PF00009.27 RKO95215.1 - 0.16 11.5 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Aldedh PF00171.22 RKO95216.1 - 4e-52 177.3 0.0 4.4e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 RKO95216.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Arg_tRNA_synt_N PF03485.16 RKO95217.1 - 0.003 18.1 0.3 0.008 16.7 0.0 1.9 2 1 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain Rubella_E2 PF05749.11 RKO95217.1 - 6.4 6.2 6.5 34 3.8 0.0 2.0 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 SH3_9 PF14604.6 RKO95219.1 - 2.6e-07 30.4 0.1 5e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO95219.1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain TMEM154 PF15102.6 RKO95219.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family RCR PF12273.8 RKO95219.1 - 0.032 14.9 0.1 0.067 13.8 0.1 1.7 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Tweety PF04906.13 RKO95219.1 - 0.098 11.3 0.1 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Tweety EphA2_TM PF14575.6 RKO95219.1 - 0.14 13.1 0.0 0.18 12.7 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FMN_red PF03358.15 RKO95221.1 - 0.00095 18.9 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase PH PF00169.29 RKO95222.1 - 9.7e-06 26.0 0.0 1.4e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 PH domain ABC_tran_Xtn PF12848.7 RKO95222.1 - 0.051 13.6 2.4 0.091 12.8 2.4 1.4 1 0 0 1 1 1 0 ABC transporter Es2 PF09751.9 RKO95222.1 - 0.074 12.8 0.5 0.11 12.2 0.5 1.4 1 1 0 1 1 1 0 Nuclear protein Es2 DUF4407 PF14362.6 RKO95222.1 - 0.11 11.9 1.7 0.13 11.6 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Helicase_C PF00271.31 RKO95223.1 - 3.3e-18 66.1 0.0 5.7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 RKO95223.1 - 3.1e-17 63.0 4.3 3.1e-17 63.0 4.3 1.5 2 0 0 2 2 2 1 RecQ zinc-binding Suf PF05843.14 RKO95224.1 - 0.03 14.3 0.0 0.036 14.1 0.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Suf PF05843.14 RKO95225.1 - 2.8 7.8 13.6 3.5 7.5 13.6 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 RKO95225.1 - 4.3 7.2 21.5 4.9 7.0 21.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RrnaAD PF00398.20 RKO95226.1 - 2.7e-50 170.9 0.0 3e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 RKO95226.1 - 2.7e-07 31.2 0.0 4.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO95226.1 - 5.2e-05 23.8 0.0 8.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 RKO95226.1 - 0.00021 21.1 0.0 0.0003 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 RKO95226.1 - 0.00056 19.3 0.0 0.00077 18.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.18 RKO95226.1 - 0.00089 18.6 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 RKO95226.1 - 0.0022 18.7 0.0 0.0037 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO95226.1 - 0.0029 17.5 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO95226.1 - 0.03 14.1 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 RKO95226.1 - 0.038 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DOT1 PF08123.13 RKO95226.1 - 0.047 13.2 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.15 RKO95226.1 - 0.067 12.8 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AAA_lid_4 PF17864.1 RKO95226.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 RuvB AAA lid domain Methyltransf_28 PF02636.17 RKO95226.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 RKO95226.1 - 0.17 11.4 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GATase PF00117.28 RKO95228.1 - 7.6e-13 48.7 0.0 8.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RKO95228.1 - 0.0015 18.3 0.3 0.0036 17.1 0.3 1.6 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 RKO95228.1 - 0.012 15.3 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Atx10homo_assoc PF09759.9 RKO95229.1 - 1.1e-30 105.5 0.2 1.3e-30 105.3 0.2 1.0 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain HEAT PF02985.22 RKO95229.1 - 0.075 13.3 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 HEAT repeat KilA-N PF04383.13 RKO95230.1 - 1.6e-05 24.7 0.1 0.0012 18.7 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain Brix PF04427.18 RKO95231.1 - 7.4e-11 42.5 0.0 9.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pkinase PF00069.25 RKO95232.1 - 1.5e-50 172.0 0.1 1.6e-50 171.9 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95232.1 - 3.4e-28 98.7 0.0 3.8e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RKO95232.1 - 0.00016 20.7 0.2 0.00019 20.5 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RKO95232.1 - 0.16 11.3 0.0 0.19 11.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like EXS PF03124.14 RKO95234.1 - 2.4e-57 194.8 22.4 2.7e-57 194.6 22.4 1.0 1 0 0 1 1 1 1 EXS family Pkinase PF00069.25 RKO95235.1 - 1.6e-08 34.2 0.0 1.7e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95235.1 - 0.0016 17.8 0.0 0.0017 17.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Acyl-CoA_dh_N PF02771.16 RKO95236.1 - 4.8e-11 43.3 0.0 6.3e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RKO95236.1 - 3.4e-08 33.6 0.0 8.4e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Retrotran_gag_2 PF14223.6 RKO95237.1 - 2.7e-07 30.3 0.0 3.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 RKO95237.1 - 2.9e-06 26.8 0.3 6.6e-06 25.7 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 RKO95237.1 - 1.3e-05 24.9 0.1 2.9e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type EBV-NA1 PF02905.14 RKO95238.1 - 0.082 12.7 0.2 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain DUF2072 PF09845.9 RKO95239.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein XAP5 PF04921.14 RKO95240.1 - 2e-61 208.0 0.6 2.2e-61 207.8 0.6 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator Pkinase PF00069.25 RKO95241.1 - 5.7e-19 68.5 0.0 6.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95241.1 - 4.5e-10 39.2 0.0 5.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sec16 PF12932.7 RKO95242.1 - 4e-05 24.2 0.1 8.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DUF4407 PF14362.6 RKO95242.1 - 1.9 7.8 4.4 2.4 7.4 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cpn60_TCP1 PF00118.24 RKO95243.1 - 1.9e-36 125.8 1.4 2.1e-36 125.6 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 RKO95244.1 - 0.00039 21.2 4.3 0.014 16.3 0.1 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ELYS-bb PF16687.5 RKO95244.1 - 0.029 13.0 0.0 0.067 11.8 0.0 1.5 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Fasciclin PF02469.22 RKO95245.1 - 5.4e-07 29.9 0.0 1.4e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain PIN_6 PF17146.4 RKO95248.1 - 9.5e-09 35.7 0.4 9.5e-09 35.7 0.4 2.0 2 0 0 2 2 2 1 PIN domain of ribonuclease DUF4050 PF13259.6 RKO95248.1 - 0.15 12.4 0.9 0.21 11.9 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Coatomer_g_Cpla PF16381.5 RKO95250.1 - 4.7e-23 81.5 0.1 7.3e-23 80.9 0.1 1.3 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform AAA_12 PF13087.6 RKO95251.1 - 3.3e-10 39.9 0.0 3.8e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 RKO95252.1 - 6.3e-17 61.9 0.3 6.9e-17 61.7 0.3 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 RKO95252.1 - 0.0039 17.0 0.1 0.0084 15.9 0.1 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 RKO95252.1 - 0.0076 16.0 0.0 0.0083 15.9 0.0 1.0 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 RKO95252.1 - 0.017 14.4 1.3 0.024 13.9 0.5 1.5 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IFT57 PF10498.9 RKO95253.1 - 2.2e-30 105.9 1.7 2.3e-30 105.8 1.7 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Tropomyosin PF00261.20 RKO95253.1 - 0.00044 19.7 1.3 0.00044 19.7 1.3 1.6 1 1 1 2 2 2 1 Tropomyosin EzrA PF06160.12 RKO95253.1 - 0.0019 16.5 0.1 0.0021 16.3 0.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Bcr-Abl_Oligo PF09036.10 RKO95253.1 - 0.0029 17.6 1.4 1.7 8.7 0.0 2.8 2 1 1 3 3 3 1 Bcr-Abl oncoprotein oligomerisation domain T7SS_ESX_EspC PF10824.8 RKO95253.1 - 0.0041 17.6 7.7 0.067 13.7 3.3 2.6 1 1 2 3 3 3 1 Excreted virulence factor EspC, type VII ESX diderm Mod_r PF07200.13 RKO95253.1 - 0.0041 17.2 1.3 0.0056 16.8 1.3 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein YscO PF07321.12 RKO95253.1 - 0.0056 16.6 2.4 0.0057 16.6 1.4 1.5 1 1 0 1 1 1 1 Type III secretion protein YscO DUF1664 PF07889.12 RKO95253.1 - 0.0073 16.3 2.9 0.044 13.8 1.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 RKO95253.1 - 0.011 16.3 4.2 0.038 14.6 4.1 1.9 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMF_TATA_bd PF12325.8 RKO95253.1 - 0.012 15.9 4.5 0.21 11.8 1.0 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Baculo_PEP_C PF04513.12 RKO95253.1 - 0.019 15.0 3.3 0.04 14.0 3.3 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CENP-F_leu_zip PF10473.9 RKO95253.1 - 0.023 14.7 4.9 0.12 12.4 1.1 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Snapin_Pallidin PF14712.6 RKO95253.1 - 0.025 15.0 0.9 0.025 15.0 0.9 1.9 1 1 1 2 2 2 0 Snapin/Pallidin Spc7 PF08317.11 RKO95253.1 - 0.028 13.3 3.7 0.047 12.6 3.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 RKO95253.1 - 0.032 14.3 7.4 0.87 9.7 7.7 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein UPF0449 PF15136.6 RKO95253.1 - 0.038 14.4 0.9 0.076 13.5 0.2 1.8 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 CENP-H PF05837.12 RKO95253.1 - 0.046 14.1 4.4 0.063 13.7 4.4 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.12 RKO95253.1 - 0.053 14.1 6.8 2.5 8.8 0.1 3.0 1 1 2 3 3 3 0 SlyX DASH_Hsk3 PF08227.11 RKO95253.1 - 0.058 13.8 0.3 1.2 9.6 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like TMPIT PF07851.13 RKO95253.1 - 0.059 12.6 0.8 0.07 12.4 0.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 RKO95253.1 - 0.072 13.6 3.2 2.7 8.5 0.3 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FapA PF03961.13 RKO95253.1 - 0.072 11.7 0.4 0.087 11.4 0.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALMT PF11744.8 RKO95253.1 - 0.083 11.7 0.3 0.094 11.5 0.3 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter ATG16 PF08614.11 RKO95253.1 - 0.085 13.1 9.5 0.76 10.0 9.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 RKO95253.1 - 0.087 13.3 2.5 0.58 10.6 0.9 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Swi5 PF07061.11 RKO95253.1 - 0.098 12.8 3.0 0.16 12.1 0.4 2.0 1 1 1 2 2 2 0 Swi5 Macoilin PF09726.9 RKO95253.1 - 0.1 11.1 1.9 0.12 10.9 1.9 1.1 1 0 0 1 1 1 0 Macoilin family DUF3300 PF11737.8 RKO95253.1 - 0.11 12.1 0.3 0.13 11.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) ABC_tran_CTD PF16326.5 RKO95253.1 - 0.12 12.6 4.9 0.12 12.6 1.1 2.3 1 1 1 2 2 2 0 ABC transporter C-terminal domain KxDL PF10241.9 RKO95253.1 - 0.13 12.6 1.9 2.2 8.6 0.0 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF4140 PF13600.6 RKO95253.1 - 0.15 12.5 8.3 5 7.6 5.1 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 RKO95253.1 - 0.15 11.4 4.4 0.19 11.1 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 RKO95253.1 - 0.15 12.1 5.3 0.25 11.4 3.1 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC PF04632.12 RKO95253.1 - 0.21 10.1 3.6 0.25 9.8 3.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 RKO95253.1 - 0.23 11.7 4.9 0.68 10.2 4.9 1.7 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1690 PF07956.11 RKO95253.1 - 0.34 11.3 2.7 0.43 11.0 2.0 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) JIP_LZII PF16471.5 RKO95253.1 - 0.58 10.4 5.7 13 6.1 0.2 2.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II TEX13 PF15186.6 RKO95253.1 - 0.63 9.7 5.3 0.48 10.1 2.5 1.9 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family DLP_helical PF18709.1 RKO95253.1 - 0.66 9.1 5.1 1.2 8.3 1.0 2.1 1 1 1 2 2 2 0 Dynamin-like helical domain HalX PF08663.10 RKO95253.1 - 0.67 10.3 8.2 0.29 11.5 1.1 2.9 1 1 2 3 3 3 0 HalX domain BST2 PF16716.5 RKO95253.1 - 0.7 10.5 5.6 2.3 8.9 1.8 2.2 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Vps51 PF08700.11 RKO95253.1 - 0.9 9.7 5.1 1.5 9.0 0.1 2.6 2 1 1 3 3 3 0 Vps51/Vps67 APG6_N PF17675.1 RKO95253.1 - 1.7 9.2 5.8 13 6.3 5.8 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3138 PF11336.8 RKO95253.1 - 2.8 6.5 5.5 2.2 6.8 4.3 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) HEAT PF02985.22 RKO95254.1 - 0.00096 19.2 0.0 0.093 13.0 0.0 2.9 2 0 0 2 2 2 1 HEAT repeat CLASP_N PF12348.8 RKO95254.1 - 0.0024 17.5 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal Proteasom_PSMB PF10508.9 RKO95254.1 - 0.003 16.2 0.0 0.0038 15.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.7 RKO95254.1 - 0.069 13.2 0.0 0.12 12.5 0.0 1.4 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKO95254.1 - 0.085 13.3 1.7 0.4 11.1 0.1 2.0 1 1 1 2 2 2 0 HEAT repeats Adaptin_N PF01602.20 RKO95254.1 - 0.21 10.1 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Adaptin N terminal region Sec23_BS PF08033.12 RKO95255.1 - 1.9e-07 31.7 0.0 2.3e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain G-patch PF01585.23 RKO95256.1 - 4.5e-07 29.6 3.5 1.5e-06 28.0 3.5 1.9 1 1 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 RKO95256.1 - 0.0035 17.4 0.7 0.0035 17.4 0.7 1.7 2 0 0 2 2 2 1 G-patch domain DNA_pol_B PF00136.21 RKO95257.1 - 9.4e-31 107.0 0.0 1.4e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 RKO95257.1 - 8.1e-12 44.9 0.0 1.2e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 RKO95257.1 - 0.00033 19.7 0.1 0.00045 19.2 0.1 1.4 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_A_exo1 PF01612.20 RKO95257.1 - 0.024 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 3'-5' exonuclease MWFE PF15879.5 RKO95257.1 - 0.088 13.0 0.1 7.7 6.8 0.1 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit AMP-binding PF00501.28 RKO95258.1 - 6.2e-32 110.7 0.0 6.9e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.25 RKO95259.1 - 1.5e-33 116.3 0.0 1.6e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95259.1 - 1e-21 77.4 0.0 1.1e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO95259.1 - 0.019 13.7 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 RKO95259.1 - 0.14 11.5 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Rgp1 PF08737.10 RKO95260.1 - 7e-16 58.4 0.0 5.7e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 Rgp1 DER1 PF04511.15 RKO95261.1 - 2e-25 89.9 2.3 2.2e-25 89.7 2.3 1.0 1 0 0 1 1 1 1 Der1-like family ADH_N PF08240.12 RKO95262.1 - 5.8e-11 42.2 0.0 7.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 RKO95262.1 - 0.00073 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ACC_central PF08326.12 RKO95263.1 - 1.9e-17 62.8 0.1 3.5e-17 61.9 0.1 1.4 1 1 0 1 1 1 1 Acetyl-CoA carboxylase, central region PRODH PF18327.1 RKO95263.1 - 0.049 13.9 0.9 0.15 12.3 0.9 1.9 1 0 0 1 1 1 0 Proline utilization A proline dehydrogenase N-terminal domain Cu-oxidase_2 PF07731.14 RKO95265.1 - 5.6e-20 71.5 0.0 8e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Multicopper oxidase DUF2045 PF09741.9 RKO95266.1 - 1.4e-15 57.4 0.0 1.8e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) Thioredoxin PF00085.20 RKO95267.1 - 1.3e-25 89.4 0.0 1.4e-19 70.0 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.6 RKO95267.1 - 0.00043 20.4 0.1 0.0014 18.8 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RKO95267.1 - 0.09 13.2 0.0 0.56 10.7 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 RKO95267.1 - 0.093 13.1 0.0 0.39 11.1 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like Methyltransf_34 PF11312.8 RKO95268.1 - 1.9e-18 66.8 0.0 2.3e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase HMGL-like PF00682.19 RKO95269.1 - 5.3e-27 95.0 0.1 5.7e-27 94.9 0.1 1.0 1 0 0 1 1 1 1 HMGL-like NuDC PF16273.5 RKO95270.1 - 0.17 12.4 1.4 0.32 11.6 1.4 1.5 1 0 0 1 1 1 0 Nuclear distribution C domain Totivirus_coat PF05518.11 RKO95270.1 - 0.39 8.7 10.9 0.44 8.5 10.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein Retrotrans_gag PF03732.17 RKO95271.1 - 8.3e-05 22.8 0.2 0.00017 21.8 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Helicase_C PF00271.31 RKO95272.1 - 5.6e-30 104.0 0.0 2.6e-29 101.8 0.0 1.9 1 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKO95272.1 - 2.5e-17 63.2 0.1 6.7e-17 61.8 0.0 1.7 2 1 1 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 RKO95272.1 - 0.057 12.6 0.0 0.075 12.2 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 RKO95272.1 - 0.1 11.4 0.3 1.9 7.2 0.1 2.6 1 1 1 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 K_oxygenase PF13434.6 RKO95272.1 - 0.18 10.9 0.0 5.5 6.0 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Marek_A PF02124.15 RKO95273.1 - 0.079 12.8 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 Marek's disease glycoprotein A Dynamitin PF04912.14 RKO95275.1 - 3e-18 66.3 0.6 3.2e-18 66.2 0.6 1.0 1 0 0 1 1 1 1 Dynamitin Spc7 PF08317.11 RKO95275.1 - 0.008 15.1 0.3 0.0091 14.9 0.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein HalX PF08663.10 RKO95275.1 - 0.017 15.4 4.6 0.024 14.9 3.6 1.8 1 1 1 2 2 2 0 HalX domain BST2 PF16716.5 RKO95275.1 - 0.045 14.3 1.3 0.069 13.7 1.3 1.2 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 AAR2 PF05282.11 RKO95275.1 - 0.11 11.9 0.1 0.12 11.8 0.1 1.0 1 0 0 1 1 1 0 AAR2 protein YabA PF06156.13 RKO95275.1 - 0.11 13.1 0.9 0.17 12.5 0.9 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Hira PF07569.11 RKO95277.1 - 4.2e-08 33.2 0.0 5.7e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 TUP1-like enhancer of split PNP_UDP_1 PF01048.20 RKO95278.1 - 1.6e-08 34.1 0.3 1.6e-08 34.1 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Dynein_C PF18199.1 RKO95279.1 - 6.8e-62 209.4 0.1 8.1e-62 209.2 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain APH_6_hur PF04655.14 RKO95279.1 - 0.072 12.5 0.1 2 7.7 0.0 2.1 2 0 0 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase GATA PF00320.27 RKO95280.1 - 2.1e-08 33.6 5.2 4.2e-08 32.7 5.2 1.5 1 0 0 1 1 1 1 GATA zinc finger LigB PF02900.18 RKO95281.1 - 5.8e-12 45.3 0.0 6.3e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF2059 PF09832.9 RKO95281.1 - 0.041 13.9 0.0 0.11 12.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2059) MOZ_SAS PF01853.18 RKO95282.1 - 1.4e-26 93.2 0.0 1.9e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RKO95282.1 - 4.3e-10 39.0 0.3 6.7e-10 38.4 0.3 1.3 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 RKO95282.1 - 0.00036 20.9 0.0 0.00067 20.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKO95282.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family PH PF00169.29 RKO95283.1 - 0.0096 16.4 0.1 0.014 15.9 0.1 1.2 1 0 0 1 1 1 1 PH domain WD40 PF00400.32 RKO95284.1 - 4.8e-06 27.2 0.0 0.24 12.3 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat SH3_1 PF00018.28 RKO95285.1 - 6.1e-05 22.6 0.0 0.00026 20.5 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 RKO95285.1 - 0.00056 19.7 0.1 0.0013 18.6 0.1 1.6 1 1 0 1 1 1 1 Variant SH3 domain zf-C2H2 PF00096.26 RKO95286.1 - 2.8e-11 43.2 10.0 2.3e-05 24.6 1.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO95286.1 - 1.8e-07 31.4 8.0 0.0013 19.3 1.2 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKO95286.1 - 7.3e-06 26.2 0.2 7.3e-06 26.2 0.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 RKO95286.1 - 0.0062 16.8 1.7 0.029 14.6 1.7 1.8 1 1 0 1 1 1 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 RKO95286.1 - 0.033 14.8 0.7 1.1 9.9 0.0 2.0 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 RKO95286.1 - 0.057 13.6 1.6 7.1 6.7 0.3 1.9 1 1 0 1 1 1 0 Aberrant zinc-finger FSA_C PF10479.9 RKO95287.1 - 4.3 5.3 10.8 5.8 4.9 10.8 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Cecropin PF00272.19 RKO95288.1 - 0.093 12.5 1.7 0.34 10.7 1.7 2.0 1 0 0 1 1 1 0 Cecropin family RCS1 PF07326.11 RKO95289.1 - 0.022 14.7 7.9 0.032 14.2 7.9 1.2 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 UPF0147 PF03685.13 RKO95289.1 - 0.19 11.8 0.6 0.37 10.9 0.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0147) SH3_9 PF14604.6 RKO95290.1 - 3.8e-12 45.9 0.0 5.2e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO95290.1 - 1.1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RKO95290.1 - 0.0011 18.6 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain MMR_HSR1 PF01926.23 RKO95291.1 - 2e-21 76.2 0.0 2.4e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKO95291.1 - 5.9e-08 32.4 0.0 8.3e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RKO95291.1 - 0.0022 18.1 0.1 0.18 11.8 0.1 2.1 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 RKO95291.1 - 0.016 14.2 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 RKO95291.1 - 0.11 12.8 0.0 0.15 12.3 0.0 1.4 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 RKO95294.1 - 1.5e-11 45.0 0.0 9.7e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 RKO95294.1 - 0.00043 19.8 0.0 0.00053 19.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 RKO95294.1 - 0.00065 19.9 0.1 0.019 15.2 0.1 2.2 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 RKO95294.1 - 0.015 15.1 0.0 0.017 14.9 0.0 1.0 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ank_2 PF12796.7 RKO95295.1 - 4.7e-25 88.0 0.1 3.8e-10 40.2 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKO95295.1 - 2.9e-21 75.3 0.2 6.4e-11 42.3 0.0 3.9 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RKO95295.1 - 5.7e-21 74.6 0.2 4.3e-07 30.3 0.0 4.8 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKO95295.1 - 4.4e-20 69.6 0.0 0.003 17.9 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 RKO95295.1 - 1.6e-12 47.3 0.3 0.047 14.2 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat dbPDZ_assoc PF16610.5 RKO95296.1 - 0.052 13.8 2.4 0.099 12.9 2.4 1.4 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Biotin_carb_N PF00289.22 RKO95297.1 - 3.4e-25 88.7 0.0 4.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain WD40 PF00400.32 RKO95298.1 - 7.9e-12 45.5 1.2 0.00014 22.6 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95298.1 - 0.00028 21.1 0.0 0.12 12.6 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1989 PF09347.10 RKO95298.1 - 0.015 15.0 1.9 1.2 8.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1989) PALB2_WD40 PF16756.5 RKO95298.1 - 0.026 13.5 0.0 0.55 9.1 0.0 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Nop10p PF04135.12 RKO95303.1 - 8e-22 77.0 1.5 9.4e-22 76.8 1.5 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family BAH PF01426.18 RKO95304.1 - 6.3e-13 48.6 0.0 8.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 BAH domain DUF3463 PF11946.8 RKO95304.1 - 0.066 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) GATase PF00117.28 RKO95305.1 - 9.3e-27 94.0 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 RKO95305.1 - 2.9e-05 23.9 0.2 0.00047 20.0 0.0 2.2 2 0 0 2 2 2 1 Peptidase C26 Sugar_tr PF00083.24 RKO95306.1 - 5.1e-16 58.6 7.2 5.4e-16 58.5 7.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RKO95306.1 - 3.8e-14 52.4 12.3 4.1e-14 52.3 12.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Muskelin_N PF06588.11 RKO95307.1 - 3.3e-30 105.5 0.0 3.5e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Muskelin N-terminus F5_F8_type_C PF00754.25 RKO95307.1 - 0.061 13.4 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain SMP_2 PF10144.9 RKO95308.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin CAF1 PF04857.20 RKO95309.1 - 0.011 14.9 0.1 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 CAF1 family ribonuclease CCDC53 PF10152.9 RKO95309.1 - 0.061 13.7 0.2 0.064 13.7 0.2 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FAM75 PF14650.6 RKO95309.1 - 0.096 12.2 4.8 0.11 12.0 4.8 1.1 1 0 0 1 1 1 0 FAM75 family DUF4230 PF14014.6 RKO95309.1 - 0.12 12.6 1.3 0.14 12.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) Med15 PF09606.10 RKO95309.1 - 0.45 9.2 14.8 0.52 8.9 14.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Nup54 PF13874.6 RKO95310.1 - 0.013 15.6 0.4 0.023 14.8 0.1 1.6 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Adaptin_N PF01602.20 RKO95311.1 - 6.9e-24 84.3 0.1 7.9e-24 84.1 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Ank_5 PF13857.6 RKO95312.1 - 2e-13 50.3 2.6 3.9e-11 43.0 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKO95312.1 - 2.5e-13 50.4 0.0 4.5e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKO95312.1 - 1e-11 43.9 0.5 1.8e-07 30.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 RKO95312.1 - 2.6e-11 43.8 0.5 2.7e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 RKO95312.1 - 7e-10 38.9 2.0 1.6e-07 31.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Herpes_pp85 PF04637.12 RKO95314.1 - 5.1 5.4 6.0 6.9 5.0 6.0 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CLP1_N PF16573.5 RKO95315.1 - 2.5e-21 75.7 0.0 3.1e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor zf-RING_UBOX PF13445.6 RKO95316.1 - 6.4e-08 32.5 2.3 1.1e-07 31.8 2.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 RKO95316.1 - 6.7e-07 29.1 3.3 1.1e-06 28.4 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO95316.1 - 1.2e-06 28.7 4.1 1.8e-06 28.2 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RKO95316.1 - 8e-06 25.6 5.3 1.3e-05 24.9 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKO95316.1 - 0.0019 18.1 4.9 0.0024 17.8 4.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 RKO95316.1 - 0.0045 17.1 8.6 0.024 14.8 8.7 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 RKO95316.1 - 0.0047 16.7 9.2 0.089 12.7 9.2 2.2 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 RKO95316.1 - 0.01 15.6 9.1 0.18 11.7 9.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PRIMA1 PF16101.5 RKO95316.1 - 0.016 15.2 3.2 0.023 14.8 3.2 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-RING_11 PF17123.5 RKO95316.1 - 0.027 14.2 0.7 0.05 13.4 0.7 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 RKO95316.1 - 0.041 13.7 7.8 0.062 13.1 7.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TackOD1 PF18551.1 RKO95316.1 - 0.047 13.4 2.9 0.065 12.9 2.9 1.2 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 C1_4 PF07975.12 RKO95316.1 - 0.1 12.9 4.5 0.2 11.9 4.5 1.6 1 0 0 1 1 1 0 TFIIH C1-like domain Prok-RING_1 PF14446.6 RKO95316.1 - 1.1 9.3 6.5 7.6 6.5 1.0 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_6 PF14835.6 RKO95316.1 - 1.5 8.8 9.1 9.4 6.2 9.1 2.3 1 1 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.21 RKO95316.1 - 1.7 9.0 6.4 0.89 9.8 0.9 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DUF1126 PF06565.12 RKO95317.1 - 1.8e-24 85.6 0.0 5e-11 42.3 0.0 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain Glycos_transf_4 PF00953.21 RKO95318.1 - 1.4e-15 57.6 4.0 1.8e-15 57.2 4.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 4 Adenylsucc_synt PF00709.21 RKO95319.1 - 2.1e-89 300.4 0.0 2.3e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase adh_short PF00106.25 RKO95319.1 - 0.17 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Tim44 PF04280.15 RKO95321.1 - 3.8e-29 101.7 0.0 4.6e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Tim44-like domain Dicty_REP PF05086.12 RKO95322.1 - 1.9 6.4 7.0 2.1 6.2 7.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein GSHPx PF00255.19 RKO95323.1 - 5.2e-35 119.3 0.1 6.5e-35 119.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 RKO95323.1 - 3.6e-08 33.4 0.1 8.2e-07 29.0 0.1 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKO95323.1 - 1.9e-05 24.4 0.1 0.00011 21.9 0.1 2.0 1 1 0 1 1 1 1 Redoxin NDUF_B8 PF05821.11 RKO95323.1 - 0.03 14.2 0.1 0.039 13.8 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Pkinase PF00069.25 RKO95324.1 - 1.9e-26 93.0 0.0 2.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95324.1 - 2.7e-17 62.9 0.0 3e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_pol_phi PF04931.13 RKO95325.1 - 0.00026 19.3 16.9 0.00028 19.2 16.9 1.1 1 0 0 1 1 1 1 DNA polymerase phi Nop14 PF04147.12 RKO95325.1 - 0.0036 15.6 12.5 0.0036 15.6 12.5 1.0 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 RKO95325.1 - 0.0086 14.6 5.9 0.0076 14.8 5.9 1.0 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 RKO95325.1 - 0.051 12.9 10.0 0.052 12.9 10.0 1.0 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 RKO95325.1 - 0.16 10.2 11.2 0.17 10.2 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein CAP_GLY PF01302.25 RKO95325.1 - 0.19 11.7 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 1 0 CAP-Gly domain TRAP_alpha PF03896.16 RKO95325.1 - 0.24 10.6 5.9 0.25 10.5 5.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SGT1 PF07093.11 RKO95325.1 - 0.86 8.0 6.5 0.89 7.9 6.5 1.0 1 0 0 1 1 1 0 SGT1 protein BTV_NS2 PF04514.12 RKO95325.1 - 1.6 7.5 10.4 2.1 7.1 10.4 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 CobT PF06213.12 RKO95325.1 - 2.2 7.6 12.8 2.5 7.4 12.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFB6 PF17110.5 RKO95325.1 - 2.5 7.8 6.5 3.1 7.5 6.5 1.3 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH SDA1 PF05285.12 RKO95325.1 - 2.7 7.4 19.7 2.9 7.2 19.7 1.1 1 0 0 1 1 1 0 SDA1 Nop53 PF07767.11 RKO95325.1 - 2.7 7.3 7.1 2.9 7.2 7.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Roughex PF06020.11 RKO95325.1 - 2.7 7.0 9.5 2.6 7.0 9.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Drc1-Sld2 PF11719.8 RKO95325.1 - 4 6.9 9.0 4.2 6.8 9.0 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF4637 PF15470.6 RKO95325.1 - 7.9 6.2 11.0 10 5.8 11.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) IFT57 PF10498.9 RKO95325.1 - 8.7 5.2 8.1 9.7 5.0 8.1 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF2457 PF10446.9 RKO95325.1 - 8.8 5.3 31.0 11 5.0 31.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) dDENN PF03455.19 RKO95326.1 - 3.6e-08 33.3 0.7 3.6e-08 33.3 0.7 2.4 3 0 0 3 3 3 1 dDENN domain DNA_pol_B_exo1 PF03104.19 RKO95327.1 - 4.7e-42 144.3 0.0 5.5e-42 144.1 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B_exo2 PF10108.9 RKO95327.1 - 2.7e-08 33.8 0.2 8.6e-08 32.1 0.2 1.7 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 RKO95327.1 - 3.2e-06 27.2 0.0 6.5e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 RNase_H superfamily Glyco_hydro_46 PF01374.18 RKO95330.1 - 9.8e-07 28.6 0.0 1.1e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 MgsA_C PF12002.8 RKO95330.1 - 0.09 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal DUF5496 PF17600.2 RKO95330.1 - 0.095 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5496) zf-C2H2 PF00096.26 RKO95331.1 - 9.1e-12 44.7 16.5 0.00063 20.1 0.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKO95331.1 - 3.9e-11 42.8 15.0 1.5e-06 28.4 1.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 RKO95331.1 - 1.5e-09 37.8 3.2 0.0034 17.6 0.1 3.1 3 0 0 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RKO95331.1 - 2.1e-09 37.4 13.9 0.0036 18.0 3.1 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 RKO95331.1 - 7.9e-05 22.9 6.7 0.14 12.6 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-BED PF02892.15 RKO95331.1 - 0.00083 19.3 3.9 0.59 10.2 1.6 2.7 2 1 1 3 3 3 2 BED zinc finger XPA_N PF01286.18 RKO95331.1 - 0.017 15.1 1.6 2.5 8.2 0.2 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zf-C2H2_11 PF16622.5 RKO95331.1 - 0.018 14.8 6.5 0.94 9.3 0.2 2.5 3 0 0 3 3 3 0 zinc-finger C2H2-type C1_4 PF07975.12 RKO95331.1 - 0.021 15.0 3.4 0.15 12.3 0.3 2.1 1 1 2 3 3 3 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 RKO95331.1 - 0.029 14.4 0.2 0.029 14.4 0.2 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-CHY PF05495.12 RKO95331.1 - 0.053 14.0 8.1 1 9.9 7.8 2.1 1 1 1 2 2 2 0 CHY zinc finger zf-C2H2_2 PF12756.7 RKO95331.1 - 0.088 13.2 3.9 0.76 10.2 0.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) RIG-I_C-RD PF11648.8 RKO95331.1 - 0.091 13.0 0.6 2.6 8.3 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf-C2HE PF16278.5 RKO95331.1 - 0.28 11.6 10.0 2 8.9 3.7 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-AN1 PF01428.16 RKO95331.1 - 0.49 10.6 9.2 4.8 7.4 3.3 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger zf-LYAR PF08790.11 RKO95331.1 - 0.54 10.2 0.1 0.54 10.2 0.1 3.0 3 1 0 3 3 3 0 LYAR-type C2HC zinc finger zf-MYST PF17772.1 RKO95331.1 - 0.73 9.5 6.3 0.11 12.1 1.1 2.1 2 1 0 2 2 2 0 MYST family zinc finger domain Ribosomal_S15 PF00312.22 RKO95333.1 - 2.9e-16 59.4 0.0 4.4e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 WD40 PF00400.32 RKO95334.1 - 9.4e-24 83.3 1.4 2e-09 37.9 0.1 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95334.1 - 1.4e-07 31.7 0.0 0.04 14.2 0.0 3.8 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 RKO95334.1 - 0.0007 18.0 0.0 0.00095 17.6 0.0 1.1 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 RKO95334.1 - 0.0021 16.9 0.0 0.018 13.8 0.0 2.0 1 1 1 2 2 2 2 Nup133 N terminal like HPS3_N PF14761.6 RKO95334.1 - 0.0025 17.4 0.0 0.051 13.1 0.0 2.0 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 Nup160 PF11715.8 RKO95334.1 - 0.0027 16.4 0.1 0.044 12.4 0.0 2.2 1 1 0 2 2 2 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 RKO95334.1 - 0.016 14.2 0.2 0.051 12.5 0.0 1.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain SUKH-4 PF14435.6 RKO95334.1 - 0.02 15.0 0.0 0.042 13.9 0.0 1.5 1 1 0 1 1 1 0 SUKH-4 immunity protein TCTP PF00838.17 RKO95335.1 - 2.4e-53 180.9 0.7 2.7e-53 180.7 0.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF1512 PF07431.12 RKO95335.1 - 0.06 12.3 0.0 0.072 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) ADIP PF11559.8 RKO95336.1 - 0.024 14.7 6.8 0.032 14.3 6.8 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding She9_MDM33 PF05546.11 RKO95336.1 - 0.031 14.1 2.6 0.036 13.9 2.6 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family Plant_NMP1 PF06694.11 RKO95336.1 - 0.056 12.6 0.2 0.069 12.2 0.2 1.1 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) TMF_TATA_bd PF12325.8 RKO95336.1 - 0.1 12.8 5.0 0.14 12.4 5.0 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Hemagglutinin PF00509.18 RKO95336.1 - 0.16 10.4 0.1 0.19 10.1 0.1 1.0 1 0 0 1 1 1 0 Haemagglutinin SUIM_assoc PF16619.5 RKO95338.1 - 8.8 6.5 16.3 2.9 8.0 0.8 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CS PF04969.16 RKO95340.1 - 0.13 13.3 0.1 0.16 13.0 0.1 1.4 1 1 0 1 1 1 0 CS domain ALIX_LYPXL_bnd PF13949.6 RKO95341.1 - 8.6e-15 54.8 2.5 8.6e-15 54.8 2.5 1.5 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF2383 PF09537.10 RKO95341.1 - 0.0015 18.8 2.7 0.0016 18.7 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) DUF4070 PF13282.6 RKO95341.1 - 0.0051 16.9 0.2 0.008 16.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4070) TSA PF03249.13 RKO95341.1 - 0.0098 14.7 2.4 0.012 14.5 2.4 1.1 1 0 0 1 1 1 1 Type specific antigen Methyltransf_7 PF03492.15 RKO95341.1 - 0.016 14.5 0.1 0.019 14.2 0.1 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase T3SSipB PF16535.5 RKO95341.1 - 0.079 13.4 8.1 0.1 13.1 8.1 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB MscS_porin PF12795.7 RKO95341.1 - 0.14 11.7 13.8 0.18 11.3 13.8 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GAS PF13851.6 RKO95341.1 - 0.28 10.5 6.0 1.1 8.6 6.0 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF2203 PF09969.9 RKO95341.1 - 1.2 9.8 5.8 3.3 8.5 2.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) tRNA_bind_2 PF13725.6 RKO95342.1 - 3.8e-40 138.1 2.4 9.6e-39 133.5 2.4 2.0 1 1 0 1 1 1 1 Possible tRNA binding domain TT_ORF2 PF02957.15 RKO95342.1 - 0.053 14.4 1.1 0.073 14.0 1.1 1.2 1 0 0 1 1 1 0 TT viral ORF2 CS PF04969.16 RKO95344.1 - 6.6e-07 30.2 0.0 9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 CS domain UCH_1 PF13423.6 RKO95345.1 - 3.6e-13 49.8 0.6 4e-13 49.7 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 RKO95345.1 - 2.7e-11 43.4 0.1 2.9e-11 43.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 RKO95345.1 - 0.0058 16.2 3.1 0.012 15.2 3.1 1.5 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Amidoligase_2 PF12224.8 RKO95345.1 - 0.024 14.3 1.1 0.03 14.0 1.1 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme DZR PF12773.7 RKO95345.1 - 0.041 13.9 0.2 4.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon RecR PF02132.15 RKO95345.1 - 2.7 7.6 6.7 14 5.3 0.9 2.5 2 1 0 2 2 2 0 RecR protein DUF2956 PF11169.8 RKO95346.1 - 0.0053 16.9 2.4 0.0053 16.9 2.4 2.2 1 1 0 2 2 2 1 Protein of unknown function (DUF2956) POX PF07526.11 RKO95346.1 - 0.17 12.5 9.8 0.13 12.9 4.9 2.1 1 1 1 2 2 2 0 Associated with HOX V_ATPase_I PF01496.19 RKO95346.1 - 0.45 8.4 6.2 0.48 8.3 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Chalcone_3 PF16036.5 RKO95346.1 - 0.56 10.3 8.9 0.24 11.5 1.6 2.1 1 1 1 2 2 2 0 Chalcone isomerase-like DUF148 PF02520.17 RKO95346.1 - 0.83 9.8 10.2 1.7 8.8 3.3 2.7 1 1 2 3 3 3 0 Domain of unknown function DUF148 DUF16 PF01519.16 RKO95346.1 - 1 9.9 6.7 1.6 9.3 6.4 1.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.6 RKO95346.1 - 1.9 7.7 13.0 2.4 7.4 13.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2951 PF11166.8 RKO95346.1 - 4.7 7.5 11.0 1.7 8.9 2.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) CENP-H PF05837.12 RKO95346.1 - 9.2 6.7 12.3 32 5.0 11.2 2.3 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Det1 PF09737.9 RKO95347.1 - 0.0052 15.9 0.0 0.29 10.1 0.0 2.0 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 BAR_3 PF16746.5 RKO95348.1 - 0.0002 21.1 0.0 0.00025 20.8 0.0 1.1 1 0 0 1 1 1 1 BAR domain of APPL family CHASE3 PF05227.13 RKO95348.1 - 0.13 12.2 0.9 0.17 11.8 0.9 1.1 1 0 0 1 1 1 0 CHASE3 domain Septin PF00735.18 RKO95349.1 - 1.6e-22 80.1 0.0 2.1e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.27 RKO95349.1 - 2.2e-05 24.1 0.1 3.8e-05 23.3 0.0 1.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKO95349.1 - 0.00079 19.5 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 RKO95349.1 - 0.019 15.3 0.1 0.019 15.3 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 RKO95349.1 - 0.036 13.2 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain RsgA_GTPase PF03193.16 RKO95349.1 - 0.039 13.8 0.3 0.2 11.6 0.1 2.1 2 1 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 RKO95349.1 - 0.049 13.9 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 RKO95349.1 - 0.052 13.6 0.0 5.4 7.1 0.0 2.2 1 1 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 RKO95349.1 - 0.054 13.2 0.1 0.069 12.9 0.1 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.27 RKO95349.1 - 0.1 13.1 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 RKO95349.1 - 0.11 12.4 0.1 0.36 10.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 RKO95349.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Roc PF08477.13 RKO95349.1 - 0.13 12.5 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TPR_1 PF00515.28 RKO95350.1 - 2.5e-14 52.4 2.4 1.3e-07 31.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKO95350.1 - 7.6e-13 47.5 1.4 4.5e-06 26.4 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 RKO95350.1 - 1.8e-11 43.5 5.1 6.3e-05 22.6 0.4 2.7 2 1 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 RKO95350.1 - 9.4e-09 34.8 2.4 0.00012 22.0 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKO95350.1 - 4e-05 23.3 0.1 0.7 10.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKO95350.1 - 5.2e-05 23.7 1.8 0.099 13.5 0.4 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO95350.1 - 5.5e-05 23.2 0.5 0.0057 16.8 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKO95350.1 - 0.00093 19.4 7.6 0.19 12.1 0.1 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO95350.1 - 0.0016 19.1 1.5 0.04 14.6 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat PA28_beta PF02252.18 RKO95350.1 - 0.0017 18.1 1.0 0.32 10.7 0.1 2.1 1 1 1 2 2 2 2 Proteasome activator pa28 beta subunit BTAD PF03704.17 RKO95350.1 - 0.016 15.6 2.2 0.12 12.8 0.1 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_19 PF14559.6 RKO95350.1 - 0.064 13.8 8.1 0.91 10.1 1.6 3.5 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKO95350.1 - 0.076 13.7 13.5 0.69 10.7 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat KRTAP PF11759.8 RKO95351.1 - 0.00094 19.7 12.7 0.0017 18.9 12.7 1.3 1 0 0 1 1 1 1 Keratin-associated matrix UPF0220 PF05255.11 RKO95353.1 - 2.6e-21 75.9 0.2 2.9e-21 75.7 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) AMP-binding PF00501.28 RKO95355.1 - 9.2e-07 27.8 1.9 1e-06 27.6 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKO95355.1 - 0.00027 21.8 1.3 0.00049 21.0 1.3 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_28 PF02636.17 RKO95356.1 - 3.7e-32 112.0 0.0 5.5e-32 111.4 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 RKO95356.1 - 0.017 15.9 0.0 0.067 13.9 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Gti1_Pac2 PF09729.9 RKO95357.1 - 1.1e-46 159.3 0.4 6.3e-38 130.7 0.1 2.0 1 1 1 2 2 2 2 Gti1/Pac2 family MFS_1 PF07690.16 RKO95358.1 - 2.2e-30 105.8 34.8 2.6e-30 105.6 34.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 RKO95358.1 - 9.7e-06 24.3 9.0 1.2e-05 24.0 9.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 RKO95358.1 - 0.0015 17.5 14.8 0.0017 17.3 14.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2755 PF10954.8 RKO95358.1 - 0.02 14.8 0.2 0.066 13.1 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2755) LRR_4 PF12799.7 RKO95359.1 - 7e-34 115.3 54.5 2.5e-08 34.1 1.7 5.9 2 1 5 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO95359.1 - 5.8e-22 77.2 23.1 5.5e-06 26.0 0.8 5.6 3 3 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 RKO95359.1 - 5.8e-18 65.0 14.0 2.1e-09 37.1 4.4 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 RKO95359.1 - 2.9e-08 33.1 22.6 0.045 13.8 0.1 8.4 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 RKO95359.1 - 0.076 13.6 23.4 22 6.1 0.1 8.1 5 2 0 5 5 5 0 Leucine Rich Repeat DEAD PF00270.29 RKO95360.1 - 0.045 13.5 0.0 0.063 13.0 0.0 1.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO95361.1 - 5.3e-07 30.0 0.0 7.3e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 RKO95361.1 - 0.07 12.3 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase MLVIN_C PF18697.1 RKO95363.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain WD40 PF00400.32 RKO95364.1 - 2.2e-15 56.7 2.0 1e-07 32.5 0.8 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95364.1 - 1.7e-06 28.2 0.0 0.0023 18.2 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO95364.1 - 0.024 13.3 0.1 0.026 13.2 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKO95364.1 - 0.11 11.5 0.0 8.9 5.2 0.0 2.3 1 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ILVD_EDD PF00920.21 RKO95365.1 - 1.3e-96 324.3 0.1 1.4e-96 324.1 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family ABC_membrane PF00664.23 RKO95366.1 - 1.1e-27 97.3 1.8 1.3e-27 97.2 1.8 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region MLVIN_C PF18697.1 RKO95367.1 - 0.00038 20.5 0.0 0.00073 19.6 0.0 1.5 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain MLVIN_C PF18697.1 RKO95368.1 - 0.00038 20.5 0.0 0.00073 19.6 0.0 1.4 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain zf-CCHC PF00098.23 RKO95369.1 - 1.7e-05 24.7 0.6 3e-05 23.9 0.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RKO95369.1 - 0.0018 18.2 0.7 0.0036 17.2 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle TPR_2 PF07719.17 RKO95371.1 - 0.0017 18.4 0.0 0.0044 17.0 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 RKO95371.1 - 0.0023 17.6 0.1 0.0041 16.8 0.1 1.4 1 0 0 1 1 1 1 TPR repeat DUF454 PF04304.13 RKO95372.1 - 0.005 16.8 0.5 0.0061 16.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF454) DUF4400 PF14348.6 RKO95372.1 - 0.015 14.8 2.1 0.017 14.7 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) SUR7 PF06687.12 RKO95372.1 - 0.024 14.3 0.6 0.028 14.0 0.6 1.1 1 0 0 1 1 1 0 SUR7/PalI family UL45 PF05473.12 RKO95372.1 - 0.055 13.1 0.1 0.066 12.9 0.1 1.1 1 0 0 1 1 1 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF4577 PF15145.6 RKO95372.1 - 0.074 13.1 0.5 0.091 12.8 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Sarcoglycan_2 PF05510.13 RKO95372.1 - 0.097 11.4 0.1 0.12 11.2 0.1 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon Tmemb_9 PF05434.11 RKO95372.1 - 0.54 10.2 3.6 0.84 9.5 3.6 1.4 1 0 0 1 1 1 0 TMEM9 DUF962 PF06127.11 RKO95372.1 - 0.74 9.9 3.5 1 9.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF962) DUF2116 PF09889.9 RKO95372.1 - 4.3 7.4 11.1 54 3.9 11.1 2.2 1 1 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) TMEM154 PF15102.6 RKO95372.1 - 6 6.8 5.0 7.8 6.4 5.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF892 PF05974.12 RKO95373.1 - 1.4e-05 25.2 4.1 2.1e-05 24.6 4.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF892) PH PF00169.29 RKO95373.1 - 0.0016 18.9 0.0 0.007 16.9 0.0 2.1 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 RKO95373.1 - 0.0086 16.5 1.7 0.033 14.6 1.7 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 RKO95373.1 - 0.065 13.6 0.6 0.25 11.7 0.0 2.1 2 1 0 2 2 2 0 Pleckstrin homology domain Med9 PF07544.13 RKO95373.1 - 0.069 13.2 11.7 1.1 9.4 1.5 3.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 AAA_23 PF13476.6 RKO95373.1 - 0.18 12.3 1.9 0.16 12.5 0.7 1.5 2 0 0 2 2 2 0 AAA domain Allexi_40kDa PF05549.11 RKO95373.1 - 0.21 11.0 4.8 0.15 11.6 2.8 1.6 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2408 PF10303.9 RKO95373.1 - 1.2 9.7 6.8 0.14 12.7 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) FAP206 PF12018.8 RKO95373.1 - 1.3 8.5 6.7 1.9 8.0 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function ParA PF10609.9 RKO95375.1 - 8e-80 267.8 0.0 9e-80 267.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 RKO95375.1 - 0.048 13.7 0.0 0.38 10.8 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 RKO95375.1 - 0.17 11.3 0.0 0.32 10.4 0.0 1.5 1 1 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Dr_adhesin PF12393.8 RKO95376.1 - 0.21 11.9 4.6 0.41 11.0 4.6 1.5 1 0 0 1 1 1 0 Dr family adhesin E1-E2_ATPase PF00122.20 RKO95377.1 - 2.2e-09 37.1 1.2 2.5e-09 36.9 1.2 1.1 1 0 0 1 1 1 1 E1-E2 ATPase ATPase_gene1 PF09527.10 RKO95377.1 - 0.39 10.9 6.8 0.12 12.6 2.9 2.1 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter GTP_cyclohydroI PF01227.22 RKO95378.1 - 6.4e-33 113.7 0.2 6.9e-33 113.6 0.2 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I HATPase_c_2 PF13581.6 RKO95378.1 - 0.084 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Methyltransf_16 PF10294.9 RKO95379.1 - 1.2e-05 25.2 0.0 1.4e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 RKO95379.1 - 0.016 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.6 RKO95379.1 - 0.081 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MPS2 PF17060.5 RKO95380.1 - 0.0027 17.0 9.2 0.0035 16.7 9.2 1.1 1 0 0 1 1 1 1 Monopolar spindle protein 2 TMF_DNA_bd PF12329.8 RKO95380.1 - 0.0028 17.6 19.4 0.015 15.2 4.9 3.9 3 1 1 4 4 4 2 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 RKO95380.1 - 0.028 15.0 2.0 0.028 15.0 2.0 3.6 3 1 1 4 4 4 0 SlyX HrpB2 PF09487.10 RKO95380.1 - 0.043 14.2 7.5 0.64 10.5 1.0 2.5 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB2) RNA_pol_Rpb1_1 PF04997.12 RKO95380.1 - 0.062 12.6 1.7 0.071 12.4 1.7 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 FdhE PF04216.12 RKO95380.1 - 0.13 12.1 6.2 0.12 12.3 4.9 1.4 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation UPF0242 PF06785.11 RKO95380.1 - 0.27 11.3 14.3 0.39 10.8 14.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4472 PF14739.6 RKO95380.1 - 0.28 11.9 17.7 0.071 13.8 8.3 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4472) TipAS PF07739.13 RKO95380.1 - 0.67 10.5 9.2 0.94 10.0 3.8 2.4 1 1 2 3 3 3 0 TipAS antibiotic-recognition domain Med9 PF07544.13 RKO95380.1 - 0.83 9.8 14.7 3.6 7.7 4.5 3.2 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 FlaC_arch PF05377.11 RKO95380.1 - 1.5 9.2 7.4 11 6.4 0.3 3.7 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) Bap31_Bap29_C PF18035.1 RKO95380.1 - 2 8.5 12.2 1.1 9.3 2.5 3.4 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain OmpH PF03938.14 RKO95380.1 - 2.1 8.7 20.0 1.9 8.8 11.0 2.7 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 RKO95380.1 - 2.6 7.0 10.6 3.7 6.5 10.6 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PgaD PF13994.6 RKO95380.1 - 4.5 7.3 5.0 25 4.9 0.2 2.7 2 1 1 3 3 3 0 PgaD-like protein DUF4407 PF14362.6 RKO95380.1 - 4.6 6.5 14.4 8.9 5.6 14.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Occludin_ELL PF07303.13 RKO95380.1 - 5.4 7.8 10.7 1.2 9.9 2.2 2.7 1 1 2 3 3 3 0 Occludin homology domain Prefoldin_2 PF01920.20 RKO95380.1 - 6.7 6.7 18.2 0.27 11.2 4.5 3.4 3 1 0 3 3 3 0 Prefoldin subunit ERO1 PF04137.15 RKO95381.1 - 4.3e-35 121.5 0.0 4.7e-35 121.4 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Effector_1 PF04518.12 RKO95382.1 - 0.2 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Effector from type III secretion system FAM199X PF15814.5 RKO95383.1 - 2.6 7.0 4.6 3.5 6.6 4.6 1.1 1 0 0 1 1 1 0 Protein family FAM199X PCI PF01399.27 RKO95384.1 - 1.6e-20 73.6 0.6 3e-20 72.7 0.6 1.5 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 RKO95384.1 - 0.00075 19.5 0.1 0.0014 18.6 0.1 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family CNH PF00780.22 RKO95385.1 - 1.1e-13 51.5 0.0 6.3e-13 49.0 0.0 1.8 1 1 0 1 1 1 1 CNH domain DUF483 PF04467.12 RKO95386.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF483) Hydant_A_N PF05378.13 RKO95387.1 - 2.2e-28 99.1 0.0 2.5e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase N-terminal region WD40 PF00400.32 RKO95388.1 - 2.4e-24 85.1 14.8 1e-06 29.3 0.2 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95388.1 - 2.6e-05 24.4 0.1 0.061 13.6 0.0 3.7 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RKO95388.1 - 6.2e-05 22.7 0.1 0.003 17.2 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.8 RKO95388.1 - 0.00025 19.9 0.8 4.3 5.9 0.0 3.9 2 2 2 4 4 4 3 Nucleoporin Nup120/160 DUF5046 PF16465.5 RKO95388.1 - 0.00035 20.1 0.0 0.51 9.7 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) PALB2_WD40 PF16756.5 RKO95388.1 - 0.01 14.8 1.9 7.2 5.4 0.0 3.4 3 2 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Chromo PF00385.24 RKO95389.1 - 1.3e-14 53.8 1.2 5.6e-07 29.4 0.2 2.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain YL1 PF05764.13 RKO95389.1 - 1.5e-05 25.3 11.7 2e-05 24.9 11.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 RKO95389.1 - 0.0056 15.0 11.9 0.0067 14.8 11.9 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 RKO95389.1 - 0.0063 14.8 13.4 0.0074 14.6 13.4 1.0 1 0 0 1 1 1 1 Nop14-like family DUF2457 PF10446.9 RKO95389.1 - 0.011 15.0 18.7 0.013 14.6 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NAM-associated PF14303.6 RKO95389.1 - 0.017 15.8 6.2 0.026 15.3 6.2 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Cwf_Cwc_15 PF04889.12 RKO95389.1 - 0.031 14.0 21.1 0.047 13.4 21.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 RKO95389.1 - 0.23 10.2 7.6 0.29 9.9 7.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop53 PF07767.11 RKO95389.1 - 0.27 10.6 12.1 0.37 10.1 12.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) ATP-synt_E PF05680.12 RKO95389.1 - 0.44 10.9 3.8 1.1 9.6 0.9 2.3 2 0 0 2 2 2 0 ATP synthase E chain SDA1 PF05285.12 RKO95389.1 - 0.61 9.5 21.0 0.87 9.0 21.0 1.1 1 0 0 1 1 1 0 SDA1 SURF2 PF05477.11 RKO95389.1 - 1.1 9.0 10.1 1.5 8.4 10.1 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) LAT PF15234.6 RKO95389.1 - 2.2 8.0 11.9 3.3 7.4 11.9 1.2 1 0 0 1 1 1 0 Linker for activation of T-cells Methyltransf_25 PF13649.6 RKO95392.1 - 1.5e-10 41.6 0.1 2.3e-10 41.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RKO95392.1 - 6.1e-10 39.0 0.0 8.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 RKO95392.1 - 7.6e-09 35.5 0.1 9.4e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO95392.1 - 2e-08 34.3 0.0 2.4e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO95392.1 - 6.7e-08 33.1 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 RKO95392.1 - 3.3e-05 23.0 0.1 3.4e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 RKO95392.1 - 0.00024 20.5 0.0 0.00027 20.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 RKO95392.1 - 0.00047 19.8 0.1 0.0006 19.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 RKO95392.1 - 0.0016 18.4 0.2 0.0024 17.8 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 RKO95392.1 - 0.0029 17.8 0.0 0.0034 17.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 RKO95392.1 - 0.0032 17.2 0.0 0.0037 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 RKO95392.1 - 0.0033 16.8 0.1 0.0037 16.6 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RKO95392.1 - 0.0067 17.2 0.0 0.012 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 RKO95392.1 - 0.0068 15.7 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 RKO95392.1 - 0.028 14.2 0.1 0.03 14.0 0.1 1.1 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 RKO95392.1 - 0.1 12.6 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 RKO95392.1 - 0.11 11.8 0.0 5 6.4 0.0 2.1 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G PH PF00169.29 RKO95393.1 - 7.1e-12 45.8 0.0 9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 PH domain p31comet PF06581.12 RKO95394.1 - 0.034 13.3 0.0 0.04 13.1 0.0 1.0 1 0 0 1 1 1 0 Mad1 and Cdc20-bound-Mad2 binding RNA_pol_Rpb1_5 PF04998.17 RKO95395.1 - 8.8e-13 48.3 0.0 1e-12 48.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Ufd2P_core PF10408.9 RKO95397.1 - 3.2e-16 59.1 0.0 4.5e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core Sec10 PF07393.11 RKO95398.1 - 5.1e-27 94.6 0.3 5.4e-27 94.5 0.3 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF1439 PF07273.12 RKO95398.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1439) UTP25 PF06862.12 RKO95401.1 - 4.6e-74 249.9 0.0 5.3e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 RKO95401.1 - 7e-05 22.7 0.4 0.18 11.6 0.0 2.7 2 1 0 3 3 3 2 DEAD/DEAH box helicase KH_1 PF00013.29 RKO95402.1 - 1.2e-12 47.5 3.1 2.1e-05 24.2 0.1 2.6 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 RKO95402.1 - 0.0057 16.5 0.5 1.6 8.6 0.0 2.3 2 0 0 2 2 2 2 KH domain Transket_pyr PF02779.24 RKO95403.1 - 1.5e-33 116.0 0.3 1.6e-33 115.8 0.3 1.0 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Ribosomal_S5 PF00333.20 RKO95403.1 - 0.043 13.8 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain SF3b1 PF08920.10 RKO95404.1 - 4.4e-12 46.5 0.2 7.7e-12 45.8 0.2 1.5 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 Pex14_N PF04695.13 RKO95404.1 - 0.0089 16.7 0.3 0.014 16.0 0.3 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Shadoo PF14999.6 RKO95404.1 - 0.042 14.0 0.6 0.042 14.0 0.6 2.2 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective AIM3 PF17096.5 RKO95404.1 - 0.29 12.1 3.6 0.58 11.1 3.6 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Ras PF00071.22 RKO95406.1 - 3.6e-19 68.9 0.1 4e-19 68.8 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO95406.1 - 3.7e-15 56.2 0.0 4.3e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 RKO95406.1 - 0.00087 18.8 0.0 0.0009 18.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial TniB protein Arf PF00025.21 RKO95406.1 - 0.0017 17.8 0.0 0.0018 17.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RKO95406.1 - 0.0036 16.7 0.0 0.004 16.5 0.0 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKO95406.1 - 0.005 16.9 0.0 0.0058 16.7 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKO95406.1 - 0.0059 16.5 0.0 0.006 16.5 0.0 1.1 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 RKO95406.1 - 0.0061 16.8 0.0 0.0067 16.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 RKO95406.1 - 0.007 16.8 0.0 0.007 16.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 RKO95406.1 - 0.0089 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.18 RKO95406.1 - 0.0089 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Septin IstB_IS21 PF01695.17 RKO95406.1 - 0.0098 15.6 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 RKO95406.1 - 0.012 15.6 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 RKO95406.1 - 0.014 14.9 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 P-loop containing dynein motor region VirE PF05272.11 RKO95406.1 - 0.034 13.9 0.0 0.035 13.8 0.0 1.0 1 0 0 1 1 1 0 Virulence-associated protein E AAA_25 PF13481.6 RKO95406.1 - 0.037 13.6 0.1 0.051 13.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 RKO95406.1 - 0.039 14.5 0.0 0.088 13.3 0.0 1.5 1 1 1 2 2 2 0 ABC transporter MCM PF00493.23 RKO95406.1 - 0.049 12.7 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 MCM P-loop domain AAA_24 PF13479.6 RKO95406.1 - 0.051 13.3 0.0 0.063 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 RKO95406.1 - 0.074 13.0 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 RKO95406.1 - 0.075 12.2 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.13 RKO95406.1 - 0.087 12.0 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Pox_A32 PF04665.12 RKO95406.1 - 0.12 11.9 0.1 0.13 11.7 0.1 1.3 1 1 0 1 1 1 0 Poxvirus A32 protein Ribosomal_L24e PF01246.20 RKO95407.1 - 3.4e-33 113.7 5.5 3.7e-33 113.6 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L24e DUF3730 PF12530.8 RKO95409.1 - 0.031 13.9 0.8 0.057 13.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Dynamin_M PF01031.20 RKO95410.1 - 7.4e-47 159.9 0.0 2.1e-46 158.4 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 RKO95410.1 - 1.1e-33 116.7 0.0 1.7e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Dynamin family DDHD PF02862.17 RKO95412.1 - 1.8e-26 93.7 0.0 3.7e-26 92.7 0.0 1.4 2 0 0 2 2 2 1 DDHD domain Abhydrolase_8 PF06259.12 RKO95412.1 - 0.023 14.3 0.1 0.064 12.9 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 RKO95412.1 - 0.05 12.9 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 zf-C2H2 PF00096.26 RKO95414.1 - 1.6e-05 25.1 1.1 0.035 14.6 0.1 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKO95414.1 - 5e-05 23.5 0.2 0.00029 21.1 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 RKO95414.1 - 0.008 15.9 0.4 0.12 12.1 0.2 2.1 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 RKO95414.1 - 0.0092 16.8 0.3 2.5 9.2 0.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 RKO95414.1 - 0.055 14.1 0.1 0.32 11.7 0.0 1.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 RKO95414.1 - 0.086 12.6 1.1 9.3 6.1 0.2 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type FAP206 PF12018.8 RKO95415.1 - 8.7e-22 77.9 0.2 2.2e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function YHS PF04945.13 RKO95415.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 0 0 1 1 1 0 YHS domain DinB_2 PF12867.7 RKO95417.1 - 0.021 15.4 0.6 0.031 14.8 0.6 1.2 1 0 0 1 1 1 0 DinB superfamily Cyclin PF08613.11 RKO95417.1 - 0.054 13.9 0.0 0.07 13.5 0.0 1.2 1 0 0 1 1 1 0 Cyclin Carn_acyltransf PF00755.20 RKO95418.1 - 3.5e-20 72.2 0.0 3.9e-20 72.0 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase YchF-GTPase_C PF06071.13 RKO95419.1 - 7.3e-40 135.0 0.1 9.8e-40 134.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF933) TGS PF02824.21 RKO95419.1 - 0.009 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 TGS domain DUF2462 PF09495.10 RKO95420.1 - 2.7e-08 34.4 14.7 2.7e-08 34.4 14.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) SNO PF01174.19 RKO95421.1 - 9.5e-14 51.7 0.0 1e-13 51.6 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 RKO95421.1 - 6.7e-06 25.8 0.0 6.9e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 RKO95421.1 - 0.00014 21.6 0.0 0.00015 21.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 RKO95421.1 - 0.0034 17.2 0.0 0.0035 17.2 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family C2 PF00168.30 RKO95422.1 - 7.5e-05 23.0 0.0 0.00017 21.8 0.0 1.5 1 1 0 1 1 1 1 C2 domain Ras PF00071.22 RKO95423.1 - 6.9e-32 110.3 0.0 7.9e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO95423.1 - 7.8e-26 90.7 0.0 9.4e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO95423.1 - 1.7e-08 34.1 0.0 2.4e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKO95423.1 - 7.4e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKO95423.1 - 0.0027 17.3 0.0 0.0096 15.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 RKO95423.1 - 0.021 14.6 0.0 0.036 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RKO95423.1 - 0.037 13.9 0.0 6.9 6.6 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MCM PF00493.23 RKO95423.1 - 0.068 12.3 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 RKO95423.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RKO95423.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DAP3 PF10236.9 RKO95423.1 - 0.17 11.0 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 G-alpha PF00503.20 RKO95423.1 - 0.27 10.4 0.0 0.4 9.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit zf-C4pol PF14260.6 RKO95424.1 - 1e-19 70.8 8.2 1.4e-19 70.3 8.2 1.2 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B PF00136.21 RKO95424.1 - 5.5e-14 51.7 0.0 8.2e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B Prok-RING_1 PF14446.6 RKO95424.1 - 0.021 14.8 9.3 0.031 14.2 2.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-ACC PF17848.1 RKO95424.1 - 0.083 13.0 7.1 0.56 10.3 0.1 3.3 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain C1_1 PF00130.22 RKO95424.1 - 0.24 11.3 8.0 1.7 8.6 0.7 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C6_DPF PF10170.9 RKO95424.1 - 0.28 11.6 3.9 0.67 10.4 3.9 1.7 1 1 0 1 1 1 0 Cysteine-rich domain IBR PF01485.21 RKO95424.1 - 1.2 9.4 9.7 0.51 10.6 0.8 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 RKO95424.1 - 1.3 9.1 10.5 6.7 6.8 10.7 1.9 1 1 0 1 1 1 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 RKO95424.1 - 4.3 7.4 11.6 1.8e+02 2.2 11.6 2.2 1 1 0 1 1 1 0 zinc-ribbons zf-TFIIB PF13453.6 RKO95424.1 - 5.4 6.4 8.4 4.9 6.6 3.0 2.5 2 0 0 2 2 2 0 Transcription factor zinc-finger Helicase_PWI PF18149.1 RKO95425.1 - 1.4e-21 76.8 0.0 1.9e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 N-terminal helicase PWI domain DnaJ_C PF01556.18 RKO95426.1 - 6.3e-36 123.7 0.1 7.1e-36 123.5 0.1 1.0 1 0 0 1 1 1 1 DnaJ C terminal domain Serglycin PF04360.12 RKO95427.1 - 1.4 8.9 4.2 2 8.3 4.2 1.3 1 0 0 1 1 1 0 Serglycin Iso_dh PF00180.20 RKO95428.1 - 1.8e-26 93.1 0.0 2.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-CHY PF05495.12 RKO95430.1 - 5.5e-09 36.4 10.2 1.5e-08 35.0 10.3 1.6 1 1 0 1 1 1 1 CHY zinc finger Zn_Tnp_IS1595 PF12760.7 RKO95430.1 - 1.9e-05 24.6 3.4 0.011 15.6 1.8 2.2 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.10 RKO95430.1 - 0.00017 21.7 7.2 0.0054 16.8 3.0 2.3 2 0 0 2 2 2 1 Zinc ribbon domain Zn_ribbon_SprT PF17283.2 RKO95430.1 - 0.00056 19.8 1.4 0.049 13.5 0.1 2.4 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-UDP PF14569.6 RKO95430.1 - 0.0027 17.8 2.9 0.0049 17.0 2.9 1.4 1 1 0 1 1 1 1 Zinc-binding RING-finger zf_UBZ PF18439.1 RKO95430.1 - 0.0049 16.4 6.0 1.7 8.3 0.2 3.4 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger NOB1_Zn_bind PF08772.11 RKO95430.1 - 0.0065 16.6 1.2 0.0065 16.6 1.2 1.8 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Cys_rich_KTR PF14205.6 RKO95430.1 - 0.0076 16.0 9.5 0.16 11.8 0.0 2.7 2 1 1 3 3 3 2 Cysteine-rich KTR SIR2 PF02146.17 RKO95430.1 - 0.014 15.3 1.3 0.018 15.0 1.3 1.2 1 0 0 1 1 1 0 Sir2 family zinc-ribbons_6 PF07191.12 RKO95430.1 - 0.016 15.2 6.3 0.12 12.4 6.7 2.0 1 1 1 2 2 2 0 zinc-ribbons zinc_ribbon_4 PF13717.6 RKO95430.1 - 0.017 15.0 11.2 0.8 9.7 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain C1_4 PF07975.12 RKO95430.1 - 0.036 14.3 10.2 0.25 11.6 4.7 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain HypA PF01155.19 RKO95430.1 - 0.042 13.9 1.0 0.042 13.9 1.0 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Elf1 PF05129.13 RKO95430.1 - 0.063 13.3 7.1 0.87 9.7 8.1 2.0 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.7 RKO95430.1 - 0.087 12.9 6.1 1.2 9.2 6.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon YacG PF03884.14 RKO95430.1 - 0.13 12.0 6.8 0.86 9.4 2.9 2.3 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG RNA_POL_M_15KD PF02150.16 RKO95430.1 - 0.14 12.1 6.9 3.6 7.5 0.1 3.0 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit DUF3797 PF12677.7 RKO95430.1 - 0.22 11.4 3.9 2.4 8.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) TFIIS_C PF01096.18 RKO95430.1 - 0.22 11.4 8.4 2.2 8.2 1.0 3.5 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) zf-DNL PF05180.12 RKO95430.1 - 0.33 10.9 6.0 7.1 6.7 0.3 3.0 3 0 0 3 3 3 0 DNL zinc finger Zn_Tnp_IS91 PF14319.6 RKO95430.1 - 0.45 10.6 8.0 0.39 10.8 1.5 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain LIM PF00412.22 RKO95430.1 - 0.61 10.4 8.3 9.1 6.6 8.5 2.2 1 1 1 2 2 2 0 LIM domain zinc_ribbon_9 PF14369.6 RKO95430.1 - 0.64 10.3 8.8 1.9 8.8 3.5 2.6 1 1 1 2 2 2 0 zinc-ribbon DpnI PF06044.12 RKO95430.1 - 0.65 9.6 3.7 7.3 6.2 0.9 2.0 1 1 1 2 2 2 0 Dam-replacing family zf-C2H2_4 PF13894.6 RKO95430.1 - 0.95 10.5 11.3 6.4 7.9 0.5 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger Evr1_Alr PF04777.13 RKO95430.1 - 1.1 9.7 5.8 0.73 10.3 1.0 2.1 1 1 1 2 2 2 0 Erv1 / Alr family OrfB_Zn_ribbon PF07282.11 RKO95430.1 - 2.2 8.3 5.9 0.5 10.3 1.2 2.1 2 1 1 3 3 2 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.6 RKO95430.1 - 4.6 6.8 11.6 4.3 6.9 3.8 3.1 2 1 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 RKO95430.1 - 8.2 7.1 11.7 1.6 9.4 0.6 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RKO95430.1 - 8.6 6.8 12.6 5.9 7.3 0.2 3.5 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding NUDE_C PF04880.13 RKO95431.1 - 4.5 7.7 9.0 7.1 7.1 9.0 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Costars PF14705.6 RKO95433.1 - 5.5e-25 87.3 0.1 6.1e-25 87.2 0.1 1.0 1 0 0 1 1 1 1 Costars AFG1_ATPase PF03969.16 RKO95436.1 - 5.7e-82 275.5 0.1 2.8e-81 273.2 0.1 1.8 1 1 0 1 1 1 1 AFG1-like ATPase AAA_5 PF07728.14 RKO95436.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO95436.1 - 0.0022 18.4 2.1 0.24 11.8 1.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 RKO95436.1 - 0.029 14.1 0.0 0.061 13.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RKO95436.1 - 0.084 13.1 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF3694 PF12473.8 RKO95436.1 - 0.16 12.7 0.6 0.17 12.5 0.6 1.3 1 1 0 1 1 1 0 Kinesin protein VPS9 PF02204.18 RKO95437.1 - 1.1e-15 57.7 0.0 1.7e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SPX PF03105.19 RKO95437.1 - 0.4 10.5 2.5 0.49 10.3 2.5 1.0 1 0 0 1 1 1 0 SPX domain Pkinase PF00069.25 RKO95438.1 - 3.1e-55 187.4 0.0 3.5e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95438.1 - 2e-33 115.8 0.0 2.3e-33 115.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO95438.1 - 0.00047 19.6 0.1 0.00061 19.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 RKO95438.1 - 0.0016 18.1 0.1 0.0023 17.6 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 RKO95438.1 - 0.0018 17.1 0.1 0.0023 16.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RKO95438.1 - 0.014 14.3 0.1 0.017 14.0 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 RKO95438.1 - 0.029 13.7 0.3 0.2 10.9 0.3 1.9 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 RKO95438.1 - 0.043 13.7 0.5 1.2 9.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glutaredoxin PF00462.24 RKO95439.1 - 1.1e-15 57.6 0.0 2.3e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Ank_2 PF12796.7 RKO95440.1 - 8.2e-05 23.1 0.1 0.00032 21.2 0.1 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKO95440.1 - 0.068 13.5 0.3 0.46 10.9 0.0 2.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DEAD PF00270.29 RKO95441.1 - 5.1e-15 55.7 0.0 6.6e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RKO95441.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UBN_AB PF14075.6 RKO95441.1 - 0.018 14.7 0.4 0.093 12.4 0.1 1.9 2 0 0 2 2 2 0 Ubinuclein conserved middle domain Glyco_H_20C_C PF18088.1 RKO95442.1 - 5.8e-05 23.0 0.3 0.00042 20.2 0.0 2.0 2 0 0 2 2 2 1 Glycoside Hydrolase 20C C-terminal domain PRELI PF04707.14 RKO95443.1 - 3.1e-27 95.3 0.0 3.4e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DUF3432 PF11914.8 RKO95444.1 - 0.0032 17.7 10.9 0.0032 17.7 10.9 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF3432) Peptidase_C24 PF03510.14 RKO95444.1 - 0.37 11.3 3.6 3 8.4 1.1 2.9 1 1 2 3 3 3 0 2C endopeptidase (C24) cysteine protease family Retinin_C PF04527.12 RKO95444.1 - 0.83 9.9 5.9 16 5.9 5.7 2.8 1 1 0 1 1 1 0 Drosophila Retinin like protein Acyl-CoA_dh_N PF02771.16 RKO95446.1 - 7.6e-29 100.7 0.1 1.1e-28 100.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RKO95446.1 - 3.5e-19 68.8 0.0 6.3e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ERM PF00769.19 RKO95447.1 - 8.8e-05 22.4 16.1 0.00015 21.7 16.1 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family GrpE PF01025.19 RKO95447.1 - 0.0067 16.1 11.8 0.36 10.5 4.9 2.3 1 1 1 2 2 2 2 GrpE DUF2046 PF09755.9 RKO95447.1 - 0.015 14.5 17.8 0.098 11.9 17.4 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) SPX PF03105.19 RKO95447.1 - 0.048 13.6 2.6 0.073 13.0 2.6 1.3 1 0 0 1 1 1 0 SPX domain Vac_Fusion PF02346.16 RKO95447.1 - 0.08 12.6 3.6 0.36 10.5 1.5 2.9 2 1 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 Hemagglutinin PF00509.18 RKO95447.1 - 0.11 10.9 0.6 0.17 10.3 0.6 1.2 1 0 0 1 1 1 0 Haemagglutinin APG6_N PF17675.1 RKO95447.1 - 0.14 12.7 19.5 0.93 10.0 16.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region AAA_13 PF13166.6 RKO95447.1 - 0.15 10.7 8.6 0.2 10.3 8.6 1.2 1 0 0 1 1 1 0 AAA domain THOC7 PF05615.13 RKO95447.1 - 0.18 12.0 18.0 2.1 8.6 17.9 2.2 1 1 0 1 1 1 0 Tho complex subunit 7 DUF2730 PF10805.8 RKO95447.1 - 0.23 11.6 11.2 0.12 12.5 4.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) FliD_C PF07195.12 RKO95447.1 - 0.32 10.4 10.4 12 5.3 7.3 3.4 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Atg14 PF10186.9 RKO95447.1 - 0.58 9.2 13.5 0.78 8.8 13.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 RKO95447.1 - 0.59 10.2 13.8 0.25 11.4 3.0 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PI3K_P85_iSH2 PF16454.5 RKO95447.1 - 0.82 9.3 16.0 13 5.3 15.9 2.2 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CENP-F_leu_zip PF10473.9 RKO95447.1 - 0.84 9.7 20.9 0.69 9.9 8.7 2.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.11 RKO95447.1 - 0.92 9.6 16.2 1.8 8.7 1.9 3.2 2 1 2 4 4 3 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.12 RKO95447.1 - 1.2 9.7 13.6 0.46 11.0 1.7 3.9 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.13 RKO95447.1 - 1.2 9.2 15.4 1.1 9.3 10.7 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Spc7 PF08317.11 RKO95447.1 - 1.3 7.8 19.8 0.51 9.2 9.7 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 RKO95447.1 - 1.4 8.9 18.8 1.4 9.0 11.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 RKO95447.1 - 1.5 8.9 11.5 1.7 8.7 4.5 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF16 PF01519.16 RKO95447.1 - 1.5 9.3 13.0 56 4.3 12.6 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 TMF_TATA_bd PF12325.8 RKO95447.1 - 1.7 8.9 22.0 5.4 7.3 6.4 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding FUSC PF04632.12 RKO95447.1 - 3.2 6.2 9.3 3.7 5.9 9.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Prefoldin PF02996.17 RKO95447.1 - 3.4 7.6 14.4 43 4.1 10.4 3.8 1 1 1 2 2 2 0 Prefoldin subunit Cortex-I_coil PF09304.10 RKO95447.1 - 4.6 7.5 16.6 7.1 6.9 6.2 2.5 1 1 1 2 2 2 0 Cortexillin I, coiled coil Phage_GPO PF05929.11 RKO95447.1 - 5.1 6.6 10.7 16 5.0 10.7 1.8 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4407 PF14362.6 RKO95447.1 - 6.3 6.1 16.9 19 4.5 16.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 RKO95447.1 - 7.9 5.0 11.1 18 3.8 11.1 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A ATG16 PF08614.11 RKO95447.1 - 9.6 6.4 24.7 1.2e+02 2.8 24.8 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) PMT_4TMC PF16192.5 RKO95448.1 - 9e-45 152.7 10.4 1.2e-44 152.3 10.4 1.2 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase CDC45 PF02724.14 RKO95449.1 - 5.1 5.3 13.9 5.8 5.1 13.9 1.0 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.22 RKO95450.1 - 0.00029 20.6 0.0 0.00068 19.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3242 PF11586.8 RKO95450.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Alpha-amylase PF00128.24 RKO95451.1 - 2.1e-14 53.8 0.0 2.2e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 Alpha amylase, catalytic domain WD40 PF00400.32 RKO95452.1 - 1e-27 95.8 17.2 8.2e-09 36.0 1.7 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95452.1 - 8.4e-08 32.4 0.0 0.0054 17.0 0.0 3.5 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 RKO95452.1 - 7e-07 28.9 0.0 0.016 14.6 0.0 2.2 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 RKO95452.1 - 1e-05 24.4 3.2 0.18 10.4 0.1 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKO95452.1 - 0.00022 20.3 0.1 0.6 9.0 0.0 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RKO95452.1 - 0.022 14.7 0.1 5.2 6.9 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Serglycin PF04360.12 RKO95453.1 - 1.7 8.5 8.6 2.7 7.9 8.6 1.2 1 0 0 1 1 1 0 Serglycin IATP PF04568.12 RKO95453.1 - 3.8 8.0 5.3 6.1 7.3 5.3 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Noc2 PF03715.13 RKO95454.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Noc2p family DUF2150 PF09920.9 RKO95454.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2150) Trypsin_2 PF13365.6 RKO95456.1 - 7.7e-12 46.4 0.0 1.4e-11 45.5 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain DHHA1 PF02272.19 RKO95457.1 - 0.55 10.6 3.4 0.3 11.5 0.5 2.0 2 0 0 2 2 2 0 DHHA1 domain CUE PF02845.16 RKO95459.1 - 1.5e-08 34.1 0.0 1.9e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 CUE domain PEMT PF04191.13 RKO95460.1 - 5.6e-27 94.2 0.7 6.8e-27 93.9 0.7 1.0 1 0 0 1 1 1 1 Phospholipid methyltransferase Calreticulin PF00262.18 RKO95461.1 - 7.3e-29 100.8 0.0 8.9e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Calreticulin family DUF2613 PF11021.8 RKO95461.1 - 5.9 7.1 17.7 27 5.0 17.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) RHD3 PF05879.12 RKO95462.1 - 6.2e-58 196.6 0.0 6.8e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) UQ_con PF00179.26 RKO95463.1 - 2.3e-15 56.5 0.0 2.4e-15 56.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RKO95463.1 - 0.092 13.0 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 RWD domain Helicase_C PF00271.31 RKO95464.1 - 0.00025 21.4 0.0 0.0008 19.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 RKO95467.1 - 2.3e-07 31.1 0.0 3.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO95467.1 - 2.8e-05 23.9 0.0 3.9e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 RKO95467.1 - 0.00021 21.0 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DEAD PF00270.29 RKO95467.1 - 0.00026 20.8 0.0 0.00046 20.0 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_7 PF12775.7 RKO95467.1 - 0.0056 16.2 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_19 PF13245.6 RKO95467.1 - 0.0059 17.0 0.0 0.0093 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RKO95467.1 - 0.014 15.4 0.0 0.39 10.7 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SSE PF00437.20 RKO95467.1 - 0.019 14.0 0.0 0.034 13.2 0.0 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 RKO95467.1 - 0.029 14.9 0.0 0.051 14.1 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 RKO95467.1 - 0.034 14.6 0.0 0.036 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 RKO95467.1 - 0.045 13.1 0.1 0.11 11.9 0.1 1.8 1 1 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 RKO95467.1 - 0.088 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 RKO95467.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 RKO95467.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 RKO95467.1 - 0.18 12.0 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RKO95467.1 - 0.19 10.9 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 RKO95469.1 - 5e-15 56.2 0.0 1.9e-14 54.4 0.0 1.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RKO95469.1 - 5.3e-05 23.2 0.0 0.005 16.7 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 RKO95469.1 - 6.8e-05 22.4 0.1 0.0086 15.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RKO95469.1 - 0.0099 15.6 0.0 0.097 12.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain GTP_EFTU_D2 PF03144.25 RKO95469.1 - 0.027 14.8 0.0 0.047 14.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu domain 2 AAA_22 PF13401.6 RKO95469.1 - 0.028 14.7 0.0 0.047 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RKO95469.1 - 0.031 14.2 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 RKO95469.1 - 0.038 14.5 0.1 0.078 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RKO95469.1 - 0.043 13.2 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 RKO95469.1 - 0.046 13.6 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 RKO95469.1 - 0.046 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 RKO95469.1 - 0.046 13.3 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.6 RKO95469.1 - 0.056 12.1 0.1 0.13 10.9 0.0 1.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 RKO95469.1 - 0.064 12.6 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 KaiC AAA_29 PF13555.6 RKO95469.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 RKO95469.1 - 0.083 13.3 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 RKO95469.1 - 0.086 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RKO95469.1 - 0.095 12.2 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 RKO95469.1 - 0.15 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 RKO95469.1 - 0.22 11.2 0.0 0.45 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cyclin_N PF00134.23 RKO95470.1 - 1.8e-25 89.2 0.8 3.8e-25 88.1 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 RKO95470.1 - 3.4e-16 59.4 0.2 6.4e-16 58.5 0.2 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain ATP_bind_1 PF03029.17 RKO95471.1 - 1.8e-39 135.9 0.1 2.4e-39 135.6 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 RKO95471.1 - 0.0015 18.1 0.0 0.0028 17.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RKO95471.1 - 0.0025 17.3 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Ras PF00071.22 RKO95471.1 - 0.028 14.0 0.0 0.03 13.9 0.0 1.3 1 1 0 1 1 1 0 Ras family Helicase_C PF00271.31 RKO95472.1 - 2.3e-21 76.2 0.0 8.8e-21 74.3 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain Chitin_synth_2 PF03142.15 RKO95473.1 - 2.7e-124 415.7 0.0 3.1e-124 415.5 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 RKO95473.1 - 1e-06 28.8 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 RKO95473.1 - 3.8e-06 27.0 0.0 5.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 RKO95473.1 - 1.5e-05 24.6 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 RKO95473.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Claudin_2 PF13903.6 RKO95475.1 - 0.00057 19.7 0.1 0.00057 19.7 0.1 2.2 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction TMEM37 PF15108.6 RKO95475.1 - 0.0069 16.3 2.3 0.06 13.2 2.3 2.1 1 1 0 1 1 1 1 Voltage-dependent calcium channel gamma-like subunit protein family PMP22_Claudin PF00822.20 RKO95475.1 - 0.022 14.7 2.5 0.044 13.7 2.4 1.6 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Claudin_3 PF06653.11 RKO95475.1 - 0.032 14.2 3.7 0.19 11.7 3.7 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like DUF4293 PF14126.6 RKO95475.1 - 0.035 14.3 0.8 0.073 13.3 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) 7TM_GPCR_Str PF10326.9 RKO95475.1 - 0.038 13.3 1.1 0.056 12.8 1.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str SecD_SecF PF02355.16 RKO95475.1 - 0.12 11.7 0.8 0.18 11.1 0.8 1.4 1 1 0 1 1 1 0 Protein export membrane protein Clc-like PF07062.12 RKO95475.1 - 0.24 10.8 4.1 0.35 10.3 0.1 2.1 2 0 0 2 2 2 0 Clc-like Epimerase PF01370.21 RKO95477.1 - 1.2e-18 67.5 0.0 1.7e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RKO95477.1 - 2.4e-10 40.3 0.0 5.2e-08 32.7 0.0 3.0 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 RKO95477.1 - 0.049 12.8 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 Male sterility protein GCP_N_terminal PF17681.1 RKO95479.1 - 3.6e-19 69.5 0.3 4.9e-19 69.1 0.3 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF4407 PF14362.6 RKO95479.1 - 0.016 14.6 0.3 0.025 13.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SUIM_assoc PF16619.5 RKO95479.1 - 3.7 7.7 17.5 6.2 7.0 12.8 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Tcp11 PF05794.13 RKO95481.1 - 7.5e-49 167.0 1.1 1e-48 166.6 1.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 EF-hand_8 PF13833.6 RKO95482.1 - 3.1e-06 27.0 0.1 6.9e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 RKO95482.1 - 4.7e-06 26.9 0.1 1.5e-05 25.3 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 RKO95482.1 - 0.0038 17.0 0.1 1.6 8.9 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_1 PF00036.32 RKO95482.1 - 0.009 15.5 0.6 0.61 9.8 0.0 3.0 3 1 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 RKO95482.1 - 0.036 13.6 0.1 1.8 8.2 0.0 2.8 2 0 0 2 2 2 0 EF hand CM_2 PF01817.21 RKO95482.1 - 0.07 13.5 2.3 0.086 13.2 0.7 1.9 2 0 0 2 2 2 0 Chorismate mutase type II ThiC_Rad_SAM PF01964.18 RKO95482.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Radical SAM ThiC family TcpS PF17456.2 RKO95482.1 - 0.21 11.6 0.3 0.32 11.0 0.3 1.2 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S DUF5082 PF16888.5 RKO95482.1 - 0.25 11.6 2.2 2.8 8.3 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) HSCB_C PF07743.13 RKO95482.1 - 0.33 11.5 6.0 5.2 7.6 0.9 2.9 2 2 1 3 3 3 0 HSCB C-terminal oligomerisation domain DENN PF02141.21 RKO95483.1 - 1.5e-09 38.1 0.0 2.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain Sporozoite_P67 PF05642.11 RKO95484.1 - 4.8 5.1 4.2 5.2 5.0 4.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAS_9 PF13426.7 RKO95486.1 - 9e-08 32.3 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.7 RKO95486.1 - 0.0096 15.9 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 PAS domain PAS_3 PF08447.12 RKO95486.1 - 0.019 15.2 0.0 0.027 14.8 0.0 1.2 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 RKO95486.1 - 0.066 13.5 0.0 0.34 11.2 0.0 1.9 1 1 1 2 2 2 0 PAS fold PAS PF00989.25 RKO95486.1 - 0.08 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 PAS fold Semialdhyde_dh PF01118.24 RKO95487.1 - 1.1e-29 103.3 0.1 1.5e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 RKO95487.1 - 2e-14 54.1 0.0 4.8e-14 52.9 0.0 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, dimerisation domain DapB_N PF01113.20 RKO95487.1 - 0.00054 20.1 0.1 0.00081 19.5 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 RKO95487.1 - 0.081 13.6 0.2 0.21 12.3 0.0 1.8 2 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PTCB-BRCT PF12738.7 RKO95488.1 - 5.9e-09 35.8 0.0 1.6e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 RKO95488.1 - 1.3e-05 25.5 0.0 0.052 13.9 0.0 2.7 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 RKO95488.1 - 0.15 12.5 0.0 2.4 8.6 0.0 2.5 2 1 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain TFIIA PF03153.13 RKO95489.1 - 0.067 13.2 24.2 0.081 12.9 24.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pneumo_att_G PF05539.11 RKO95489.1 - 8.3 5.9 6.8 3.9 7.0 5.0 1.4 1 1 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G EMC1_C PF07774.13 RKO95490.1 - 4.8e-09 36.2 0.0 1.3e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal MLVIN_C PF18697.1 RKO95491.1 - 0.024 14.8 0.1 0.08 13.0 0.0 1.9 2 0 0 2 2 2 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Methyltr_RsmB-F PF01189.17 RKO95493.1 - 1.3e-38 132.6 0.0 2.9e-37 128.3 0.0 2.0 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RKO95493.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase ETF_alpha PF00766.19 RKO95494.1 - 1.8e-35 120.8 1.4 1.8e-35 120.8 1.4 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 RKO95494.1 - 9.2e-32 110.4 3.1 1.5e-31 109.7 3.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Hydrophobin PF01185.18 RKO95495.1 - 3.5e-07 30.8 11.5 5e-07 30.3 11.5 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Yos1 PF08571.10 RKO95496.1 - 3.4e-18 65.7 0.0 3.8e-18 65.5 0.0 1.0 1 0 0 1 1 1 1 Yos1-like Cation_ATPase PF13246.6 RKO95497.1 - 5.3e-09 36.1 0.0 6.4e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RKO95497.1 - 3.5e-06 27.4 0.1 5.6e-06 26.8 0.1 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SUI1 PF01253.22 RKO95499.1 - 0.029 14.9 1.2 0.043 14.3 1.2 1.3 1 0 0 1 1 1 0 Translation initiation factor SUI1 PKI PF02827.16 RKO95499.1 - 0.098 12.9 0.9 0.14 12.4 0.9 1.1 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor P21-Arc PF04062.14 RKO95500.1 - 2.4e-19 70.0 0.6 2.8e-19 69.8 0.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit CytB6-F_Fe-S PF08802.10 RKO95500.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit TMF_DNA_bd PF12329.8 RKO95501.1 - 1.4e-14 53.9 7.9 1.4e-14 53.9 7.9 3.7 2 1 2 4 4 4 2 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 RKO95501.1 - 0.0054 16.8 0.6 0.0054 16.8 0.6 2.9 4 1 0 4 4 4 1 bZIP transcription factor APG6_N PF17675.1 RKO95501.1 - 0.0063 17.0 37.0 0.06 13.9 18.2 2.4 1 1 1 2 2 2 2 Apg6 coiled-coil region DUF724 PF05266.14 RKO95501.1 - 0.46 10.3 18.3 0.24 11.2 13.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) TMF_TATA_bd PF12325.8 RKO95501.1 - 0.48 10.6 28.1 0.45 10.8 1.0 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fungal_TACC PF12709.7 RKO95501.1 - 0.5 10.8 12.1 0.51 10.8 2.7 3.6 2 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins PvlArgDC PF01862.16 RKO95501.1 - 0.52 10.1 7.1 0.061 13.1 1.4 2.1 1 1 1 2 2 2 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) HALZ PF02183.18 RKO95501.1 - 1.1 9.6 6.5 5 7.4 0.2 3.6 2 1 1 3 3 3 0 Homeobox associated leucine zipper Spc7 PF08317.11 RKO95501.1 - 2.6 6.8 35.0 2.7 6.8 17.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF948 PF06103.11 RKO95501.1 - 2.7 8.3 14.1 24 5.2 7.5 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) V_ATPase_I PF01496.19 RKO95501.1 - 3.4 5.4 18.6 1.3 6.8 15.0 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family FTA4 PF13093.6 RKO95501.1 - 3.7 7.4 27.2 0.67 9.8 1.6 2.9 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 JIP_LZII PF16471.5 RKO95501.1 - 3.7 7.8 17.7 0.047 13.9 4.4 3.8 2 2 3 5 5 5 0 JNK-interacting protein leucine zipper II KIP1 PF07765.12 RKO95501.1 - 5 7.3 6.4 3 8.0 0.3 3.4 3 1 0 4 4 4 0 KIP1-like protein Fez1 PF06818.15 RKO95501.1 - 6.3 7.2 28.3 2.4 8.6 23.6 2.0 1 1 1 2 2 2 0 Fez1 FapA PF03961.13 RKO95501.1 - 6.3 5.3 16.6 11 4.5 14.5 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A ATG16 PF08614.11 RKO95501.1 - 7 6.8 44.6 0.075 13.3 28.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GAS PF13851.6 RKO95501.1 - 7.3 5.9 30.1 1.9 7.8 20.7 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Myosin_head PF00063.21 RKO95503.1 - 1.7e-20 72.9 0.0 1.9e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) LRR_8 PF13855.6 RKO95504.1 - 0.034 13.9 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Leucine rich repeat Kinesin PF00225.23 RKO95505.1 - 2.9e-53 180.9 0.0 3.2e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO95505.1 - 1.6e-20 73.5 0.0 1.5e-19 70.4 0.0 2.0 1 1 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 RKO95505.1 - 0.046 13.6 0.1 0.086 12.7 0.1 1.4 2 0 0 2 2 2 0 Bacterial dnaA protein CHDCT2 PF08074.11 RKO95507.1 - 0.034 14.3 0.0 0.06 13.5 0.0 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Pkinase PF00069.25 RKO95508.1 - 5.5e-17 62.0 0.0 9.2e-17 61.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 RKO95508.1 - 0.018 14.4 0.0 0.023 14.0 0.0 1.1 1 0 0 1 1 1 0 Kinase-like X PF00739.19 RKO95509.1 - 0.038 14.1 0.1 0.062 13.4 0.1 1.3 1 0 0 1 1 1 0 Trans-activation protein X Pkinase PF00069.25 RKO95510.1 - 6.5e-11 42.1 0.1 1.1e-10 41.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95510.1 - 2.1e-07 30.5 0.0 3e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PRIMA1 PF16101.5 RKO95510.1 - 1.9 8.6 5.8 3.2 7.8 5.8 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SIR2 PF02146.17 RKO95511.1 - 1.2e-30 106.8 0.0 1.4e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Sir2 family Pkinase PF00069.25 RKO95512.1 - 1.4e-18 67.2 0.0 3e-12 46.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95512.1 - 2.3e-12 46.8 0.0 3.7e-12 46.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO95512.1 - 3.7e-05 23.2 0.0 5.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKO95512.1 - 0.0091 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKO95512.1 - 0.025 14.5 4.7 0.14 12.1 4.7 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family PseudoU_synth_1 PF01416.20 RKO95513.1 - 1.5e-28 99.4 0.0 6.2e-28 97.4 0.0 1.8 2 0 0 2 2 2 1 tRNA pseudouridine synthase Pkinase PF00069.25 RKO95516.1 - 7.1e-06 25.6 0.0 7.4e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LSM PF01423.22 RKO95517.1 - 3.8e-18 64.9 0.0 4.6e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF2457 PF10446.9 RKO95518.1 - 0.36 9.9 20.1 0.47 9.5 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.11 RKO95518.1 - 0.49 8.9 6.0 0.66 8.5 6.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 RKO95518.1 - 3.3 7.0 10.3 4.1 6.6 10.3 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 RKO95518.1 - 6.5 4.8 9.8 8.1 4.5 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family CSTF2_hinge PF14327.6 RKO95519.1 - 7.3e-15 55.2 2.8 1.3e-14 54.4 2.8 1.4 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 RKO95519.1 - 2.2e-14 53.0 0.1 3.9e-14 52.2 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKO95519.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKO95519.1 - 0.078 12.8 0.0 0.27 11.1 0.0 1.9 1 1 0 1 1 1 0 Occluded RNA-recognition motif RGS PF00615.19 RKO95521.1 - 0.019 15.2 0.0 0.026 14.8 0.0 1.2 1 0 0 1 1 1 0 Regulator of G protein signaling domain Trp_halogenase PF04820.14 RKO95521.1 - 0.071 11.9 0.5 0.1 11.4 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Tti2 PF10521.9 RKO95521.1 - 0.092 12.3 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Tti2 family PAP_central PF04928.17 RKO95522.1 - 6.7e-13 48.2 0.0 7.5e-13 48.0 0.0 1.0 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 RKO95522.1 - 2.9e-09 37.1 0.0 5.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain ESCRT-II PF05871.12 RKO95524.1 - 9.8e-44 149.0 0.0 1.4e-43 148.5 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit dsDNA_bind PF01984.20 RKO95524.1 - 0.14 12.4 1.0 0.65 10.3 1.0 1.9 1 1 0 1 1 1 0 Double-stranded DNA-binding domain TilS PF09179.11 RKO95524.1 - 1.9 9.0 6.6 16 6.1 1.7 3.1 2 1 1 3 3 3 0 TilS substrate binding domain G-patch PF01585.23 RKO95525.1 - 1.3e-09 37.8 0.3 2.4e-09 36.9 0.3 1.5 1 0 0 1 1 1 1 G-patch domain Snf7 PF03357.21 RKO95525.1 - 0.0006 19.4 4.1 0.0093 15.6 6.1 1.8 2 0 0 2 2 2 1 Snf7 G-patch_2 PF12656.7 RKO95525.1 - 0.0014 18.6 0.2 0.0014 18.6 0.2 2.1 2 0 0 2 2 2 1 G-patch domain NAM-associated PF14303.6 RKO95525.1 - 0.015 16.0 4.8 0.028 15.1 4.8 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF3439 PF11921.8 RKO95525.1 - 0.11 12.4 15.3 0.051 13.6 12.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) NARP1 PF12569.8 RKO95525.1 - 0.2 10.5 6.4 0.25 10.2 6.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NST1 PF13945.6 RKO95525.1 - 0.41 10.7 6.9 0.63 10.1 6.9 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator CPSF100_C PF13299.6 RKO95525.1 - 0.97 9.6 5.7 1.4 9.0 5.7 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Dicty_REP PF05086.12 RKO95525.1 - 3.9 5.3 7.1 4.9 5.0 7.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RNA_pol PF00940.19 RKO95526.1 - 3.8e-23 82.0 0.2 6.5e-22 77.9 0.2 2.0 1 1 0 1 1 1 1 DNA-dependent RNA polymerase LIAS_N PF16881.5 RKO95527.1 - 7.4e-16 58.5 0.0 1.5e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 RKO95527.1 - 2.6e-12 47.4 0.1 4.3e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Propep_M14 PF02244.16 RKO95527.1 - 0.037 14.4 0.0 0.067 13.6 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase activation peptide His_biosynth PF00977.21 RKO95527.1 - 0.095 12.1 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein T2SSL PF05134.13 RKO95528.1 - 0.017 14.5 0.4 0.089 12.1 0.1 1.9 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein L PIH1 PF08190.12 RKO95529.1 - 1.1e-17 64.0 0.1 1.7e-17 63.4 0.1 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 RKO95529.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 PIH1 CS-like domain PFK PF00365.20 RKO95531.1 - 3.8e-60 203.6 0.0 4.2e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 RKO95531.1 - 0.0081 15.8 0.3 0.022 14.3 0.3 1.7 1 1 1 2 2 2 1 Diacylglycerol kinase catalytic domain IPK PF03770.16 RKO95532.1 - 1.1e-06 28.6 0.0 1.5e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase Metallophos PF00149.28 RKO95533.1 - 4.8e-39 135.0 0.2 6.4e-39 134.6 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RKO95533.1 - 0.0002 21.8 0.7 0.00041 20.7 0.7 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 RKO95533.1 - 0.12 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain zf-C3HC4_3 PF13920.6 RKO95534.1 - 9.7e-05 22.2 0.4 0.00014 21.7 0.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKO95534.1 - 0.00035 20.4 5.3 0.0013 18.6 5.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 RKO95534.1 - 0.0015 18.6 0.7 0.0027 17.7 0.7 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-RING_2 PF13639.6 RKO95534.1 - 0.0042 17.4 3.5 0.009 16.3 3.4 1.6 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 RKO95534.1 - 0.0043 16.9 0.4 0.0072 16.2 0.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Lar_restr_allev PF14354.6 RKO95534.1 - 0.062 13.7 1.7 0.097 13.1 1.7 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C3HC4_4 PF15227.6 RKO95534.1 - 0.063 13.4 3.8 0.19 11.9 3.9 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RKO95534.1 - 0.088 12.9 4.3 0.15 12.1 4.3 1.4 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 RKO95534.1 - 1 9.3 4.8 12 5.9 4.8 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 V_ATPase_I PF01496.19 RKO95536.1 - 8.8e-85 285.2 0.0 1.1e-84 284.9 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family W2 PF02020.18 RKO95537.1 - 9.1e-07 28.9 0.6 2.9e-06 27.3 0.3 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Cnd1 PF12717.7 RKO95538.1 - 5.9e-05 23.2 0.3 0.00011 22.2 0.1 1.6 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RKO95538.1 - 0.00036 19.2 0.1 0.00048 18.8 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region RTP1_C1 PF10363.9 RKO95538.1 - 0.02 15.1 0.5 0.042 14.0 0.5 1.5 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1453 PF07301.11 RKO95540.1 - 0.23 11.5 1.3 0.35 10.9 0.9 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1453) CLTH PF10607.9 RKO95541.1 - 3.4e-17 62.7 0.0 5.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RKO95541.1 - 0.74 9.9 5.3 0.28 11.2 1.0 2.4 2 0 0 2 2 2 0 LisH uDENN PF03456.18 RKO95542.1 - 3.6e-14 53.3 1.0 6.1e-14 52.5 1.0 1.4 1 0 0 1 1 1 1 uDENN domain Spore_YpjB PF09577.10 RKO95543.1 - 0.11 12.3 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Sporulation protein YpjB (SpoYpjB) Pox_polyA_pol_N PF12630.7 RKO95544.1 - 0.13 12.6 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain TrkH PF02386.16 RKO95545.1 - 2.7e-25 88.8 7.0 3.1e-25 88.6 7.0 1.0 1 0 0 1 1 1 1 Cation transport protein UbiA PF01040.18 RKO95546.1 - 1.3e-44 152.4 21.2 1.7e-44 152.0 21.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PDEase_I PF00233.19 RKO95547.1 - 1.9e-76 256.9 0.2 2.2e-76 256.7 0.2 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CH PF00307.31 RKO95548.1 - 2e-19 69.7 0.0 3.5e-19 69.0 0.0 1.4 2 0 0 2 2 2 1 Calponin homology (CH) domain Calponin PF00402.18 RKO95548.1 - 2.6e-08 33.4 3.8 4.6e-08 32.5 3.8 1.5 1 0 0 1 1 1 1 Calponin family repeat Peptidase_S10 PF00450.22 RKO95549.1 - 8.5e-65 219.8 0.1 1e-64 219.5 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase CAP_N PF01213.19 RKO95549.1 - 7.7 5.9 4.8 12 5.3 4.8 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TPR_19 PF14559.6 RKO95550.1 - 1.6e-08 34.9 5.1 0.0014 19.1 2.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKO95550.1 - 4e-08 32.8 1.3 0.11 12.7 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO95550.1 - 1.1e-06 29.2 4.4 4.6e-05 24.0 1.2 3.4 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 RKO95550.1 - 0.00027 20.7 0.1 0.00055 19.7 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 RKO95550.1 - 0.00098 18.9 1.5 0.56 10.1 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKO95550.1 - 0.0047 17.6 10.3 0.65 11.0 0.1 5.1 3 1 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKO95550.1 - 0.01 16.4 3.5 44 5.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKO95550.1 - 0.01 16.1 6.0 0.31 11.4 0.2 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 RKO95550.1 - 0.071 13.3 4.1 0.071 13.3 0.9 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 RKO95550.1 - 0.12 12.7 0.8 1.1e+02 3.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKO95550.1 - 0.21 11.7 1.7 3.2 8.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO95550.1 - 0.21 11.8 4.0 9.3 6.6 0.0 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DSPc PF00782.20 RKO95551.1 - 1.8e-20 73.1 0.0 1.9e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKO95551.1 - 8.3e-05 22.3 0.0 9.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RKO95551.1 - 0.018 15.2 0.0 0.021 15.0 0.0 1.1 1 0 0 1 1 1 0 Inositol hexakisphosphate DSPn PF14671.6 RKO95551.1 - 0.18 12.3 0.0 0.21 12.0 0.0 1.1 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Romo1 PF10247.9 RKO95552.1 - 0.086 13.2 0.8 0.14 12.5 0.8 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DHC_N2 PF08393.13 RKO95553.1 - 7.1e-94 315.1 0.1 7.9e-94 315.0 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 RKO95554.1 - 5.6e-47 160.3 0.0 7.5e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 RKO95554.1 - 8.4e-06 25.8 0.0 1.7e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKO95554.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 RKO95554.1 - 0.21 11.0 0.1 0.32 10.4 0.1 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF3835 PF12927.7 RKO95555.1 - 0.45 11.4 0.0 0.45 11.4 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3835) Pox_Ag35 PF03286.14 RKO95555.1 - 0.75 9.6 5.7 1.7 8.4 5.7 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein TP2 PF01254.18 RKO95555.1 - 1.4 9.6 4.4 3.8 8.1 4.4 1.7 1 0 0 1 1 1 0 Nuclear transition protein 2 DUF1325 PF07039.11 RKO95556.1 - 1.4e-11 44.6 0.0 1.6e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 RKO95556.1 - 0.02 14.7 0.3 5.6 6.9 0.0 2.1 1 1 1 2 2 2 0 DNA repair protein Crb2 Tudor domain Lipoprot_C PF08794.10 RKO95556.1 - 0.11 12.5 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Lipoprotein GNA1870 C terminal like SUV3_C PF12513.8 RKO95557.1 - 1.6e-13 50.4 0.2 2.5e-13 49.7 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Ribosomal_L6 PF00347.23 RKO95558.1 - 3.8e-10 40.3 0.0 3.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 LRR_9 PF14580.6 RKO95559.1 - 9.3e-49 165.3 0.2 1e-48 165.1 0.2 1.0 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RKO95559.1 - 6.4e-12 45.5 5.9 2.2e-05 24.7 0.2 3.6 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO95559.1 - 1.5e-09 37.5 19.3 4.2e-06 26.4 2.3 2.5 1 1 2 3 3 3 3 Leucine rich repeat UQ_con PF00179.26 RKO95560.1 - 4.8e-21 74.9 0.0 6.2e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKO95560.1 - 0.0026 17.4 0.0 0.0049 16.6 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic E2 family B Enterotoxin_HS1 PF08090.11 RKO95561.1 - 0.012 15.6 2.4 0.012 15.6 2.4 2.0 2 0 0 2 2 2 0 Heat stable E.coli enterotoxin 1 PA PF02225.22 RKO95562.1 - 1.1e-05 25.4 1.0 4.5e-05 23.4 0.5 2.2 2 1 0 2 2 2 1 PA domain Ribosomal_L19e PF01280.20 RKO95564.1 - 4.3e-40 137.1 1.8 4.7e-40 137.0 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L19e Pterin_bind PF00809.22 RKO95564.1 - 0.11 12.1 0.0 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Pterin binding enzyme Ribosomal_L28e PF01778.17 RKO95566.1 - 2.3e-28 99.2 0.0 2.5e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF5090 PF17009.5 RKO95567.1 - 1.5 8.7 5.7 3.5 7.5 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) DKCLD PF08068.12 RKO95568.1 - 4.7e-31 106.6 1.5 5.1e-30 103.3 0.8 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 RKO95568.1 - 1.2e-23 83.0 1.0 2e-23 82.3 1.0 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 RKO95568.1 - 7e-23 81.6 0.2 8.9e-20 71.6 0.2 3.1 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 RKO95568.1 - 9.9e-06 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 PUA domain TAFII28 PF04719.14 RKO95569.1 - 0.23 11.6 0.3 0.35 11.0 0.3 1.2 1 0 0 1 1 1 0 hTAFII28-like protein conserved region RNA_pol_Rpc4 PF05132.14 RKO95571.1 - 3e-12 47.2 0.0 3.3e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase III RPC4 Med3 PF11593.8 RKO95572.1 - 1.8 7.7 4.9 2.2 7.4 4.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal WD40 PF00400.32 RKO95574.1 - 1.4e-31 108.0 3.0 7.2e-07 29.8 0.0 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95574.1 - 5.4e-14 52.3 0.0 0.023 15.0 0.0 5.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKO95574.1 - 4e-06 26.9 0.0 0.15 11.9 0.0 3.9 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 RKO95574.1 - 0.00058 18.9 0.3 2.3 7.1 0.0 3.4 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VWA_2 PF13519.6 RKO95577.1 - 1.1e-08 35.7 0.0 1.6e-06 28.7 0.0 2.1 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 RKO95577.1 - 7.6e-06 26.3 0.0 2.2e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain SNAP-25 PF00835.19 RKO95577.1 - 0.019 15.3 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 SNAP-25 family VWA_CoxE PF05762.14 RKO95577.1 - 0.09 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Pkinase PF00069.25 RKO95578.1 - 5.9e-13 48.8 0.0 6.7e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain NAD_kinase PF01513.21 RKO95579.1 - 9.9e-18 64.3 0.0 1.3e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 RKO95579.1 - 0.0086 15.7 0.0 0.018 14.7 0.0 1.5 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain MFS_1 PF07690.16 RKO95580.1 - 5.4e-12 45.3 7.6 7.1e-11 41.6 0.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RKO95580.1 - 0.00017 20.6 0.3 0.00029 19.8 0.3 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 RKO95580.1 - 0.0014 17.5 0.1 0.0026 16.7 0.1 1.4 1 0 0 1 1 1 1 MFS_1 like family Spc42p PF11544.8 RKO95581.1 - 0.08 12.9 0.1 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body component Spc42p Na_H_Exchanger PF00999.21 RKO95582.1 - 4.2e-12 45.6 6.4 4.9e-12 45.3 6.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Mak16 PF04874.14 RKO95583.1 - 3.9e-22 78.7 17.0 3.9e-22 78.7 17.0 1.8 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 RKO95583.1 - 0.02 14.2 18.6 0.026 13.9 18.6 1.1 1 0 0 1 1 1 0 BUD22 Fucose_iso_N2 PF07882.12 RKO95583.1 - 0.021 14.4 0.5 0.034 13.7 0.5 1.4 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain PI3K_1B_p101 PF10486.9 RKO95583.1 - 4.2 5.0 9.7 5.2 4.7 9.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RRN3 PF05327.11 RKO95583.1 - 7 5.1 10.7 8.2 4.8 10.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AAA_9 PF12781.7 RKO95585.1 - 1.1e-92 309.1 3.1 1.4e-92 308.8 3.1 1.1 1 0 0 1 1 1 1 ATP-binding dynein motor region MT PF12777.7 RKO95585.1 - 7.7e-07 28.4 0.9 1.3e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor C2 PF00168.30 RKO95586.1 - 6.1e-17 61.8 0.0 1.5e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 C2 domain NTP_transferase PF00483.23 RKO95588.1 - 4.6e-47 160.7 0.0 5e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RKO95588.1 - 8.6e-10 39.2 0.0 1e-09 39.0 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 RKO95588.1 - 0.077 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 RKO95588.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase WD40 PF00400.32 RKO95589.1 - 3e-17 62.7 1.3 1.1e-08 35.5 0.0 2.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95589.1 - 2.7e-06 27.6 0.1 0.059 13.7 0.1 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 RKO95589.1 - 0.0021 17.4 0.1 0.15 11.4 0.0 2.0 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 RKO95589.1 - 0.036 13.0 0.0 0.063 12.2 0.0 1.4 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 RKO95589.1 - 0.15 11.4 0.0 1.6 8.0 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain HSP20 PF00011.21 RKO95590.1 - 2.7e-05 24.2 0.1 6.4e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF883 PF05957.13 RKO95590.1 - 7.6e-05 23.2 46.1 0.0097 16.5 3.7 4.3 1 1 3 4 4 4 3 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.18 RKO95590.1 - 0.00033 20.6 30.5 0.051 13.4 12.1 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 RKO95590.1 - 0.022 15.3 35.2 3.2 8.3 8.5 4.5 1 1 3 4 4 4 0 YtxH-like protein MCM PF00493.23 RKO95592.1 - 9.1e-73 244.1 0.1 1.2e-72 243.6 0.1 1.1 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 RKO95592.1 - 1.5e-18 67.0 0.3 2.4e-18 66.3 0.3 1.4 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 RKO95592.1 - 6.2e-08 32.3 0.0 3e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RKO95592.1 - 0.0038 16.9 0.0 0.0075 16.0 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 RKO95592.1 - 0.0079 16.1 0.1 0.014 15.3 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 RKO95592.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Glyco_hydro_114 PF03537.13 RKO95596.1 - 3e-74 249.2 0.2 3.9e-74 248.9 0.2 1.0 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 MLVIN_C PF18697.1 RKO95599.1 - 0.0004 20.4 0.0 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Surp PF01805.20 RKO95600.1 - 5e-14 52.0 0.0 5.6e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 Surp module Glyco_hydro_cc PF11790.8 RKO95601.1 - 1e-60 205.3 1.4 1.2e-60 205.1 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NYN PF01936.18 RKO95601.1 - 0.14 12.6 0.0 1.8 9.1 0.0 2.1 2 0 0 2 2 2 0 NYN domain RXT2_N PF08595.11 RKO95602.1 - 1.8e-11 44.3 1.4 3.3e-09 37.0 0.2 2.1 1 1 1 2 2 2 2 RXT2-like, N-terminal Thiolase_N PF00108.23 RKO95605.1 - 4.7e-31 108.1 1.3 5.2e-31 107.9 1.3 1.0 1 0 0 1 1 1 1 Thiolase, N-terminal domain FtsJ PF01728.19 RKO95607.1 - 7.1e-20 71.8 0.0 9.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Xpo1 PF08389.12 RKO95609.1 - 2.5e-14 53.6 0.0 3.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.19 RKO95609.1 - 0.03 14.2 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain Sec63 PF02889.16 RKO95610.1 - 2.8e-20 72.6 0.0 3.7e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 RKO95610.1 - 0.0052 16.6 0.1 0.0084 15.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_9 PF12781.7 RKO95611.1 - 9.3e-74 247.3 0.7 1.2e-73 246.9 0.0 1.5 2 0 0 2 2 2 1 ATP-binding dynein motor region MT PF12777.7 RKO95611.1 - 1.9e-16 60.0 0.0 3.2e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor ATG16 PF08614.11 RKO95611.1 - 0.0043 17.3 0.7 0.0043 17.3 0.7 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF948 PF06103.11 RKO95611.1 - 0.0066 16.7 0.6 0.015 15.5 0.1 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF948) EzrA PF06160.12 RKO95611.1 - 0.0073 14.5 0.3 0.011 14.0 0.3 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA DUF1664 PF07889.12 RKO95611.1 - 0.011 15.8 1.3 0.016 15.2 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 RKO95611.1 - 0.011 16.2 0.2 0.022 15.2 0.2 1.5 1 0 0 1 1 1 0 Fez1 ZapB PF06005.12 RKO95611.1 - 0.012 16.0 3.4 0.17 12.4 1.1 2.5 2 0 0 2 2 2 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 RKO95611.1 - 0.017 15.3 1.3 0.017 15.3 1.3 1.7 2 0 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain RB_A PF01858.17 RKO95611.1 - 0.046 13.6 0.1 0.28 11.0 0.0 2.2 3 0 0 3 3 3 0 Retinoblastoma-associated protein A domain DUF3450 PF11932.8 RKO95611.1 - 0.048 13.0 1.4 0.075 12.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) KLRAQ PF10205.9 RKO95611.1 - 0.05 13.8 1.4 0.13 12.5 1.4 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 RKO95611.1 - 0.056 12.3 3.4 0.04 12.8 1.0 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein Cluap1 PF10234.9 RKO95611.1 - 0.062 12.7 1.7 0.13 11.6 1.7 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 ERM PF00769.19 RKO95611.1 - 0.098 12.5 1.4 0.16 11.8 0.4 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4201 PF13870.6 RKO95611.1 - 0.71 9.6 4.1 0.46 10.2 1.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) HrpB7 PF09486.10 RKO95611.1 - 0.81 10.1 5.4 0.25 11.7 0.7 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DHR10 PF18595.1 RKO95611.1 - 1.1 9.3 5.6 2.1 8.4 1.9 2.4 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain RasGAP PF00616.19 RKO95612.1 - 2.3e-30 105.9 0.4 1.8e-27 96.4 0.4 2.2 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase ubiquitin PF00240.23 RKO95613.1 - 3.2e-34 116.5 1.7 4.9e-34 115.9 0.9 1.7 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 RKO95613.1 - 5.9e-24 84.0 3.5 1.2e-23 82.9 3.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.8 RKO95613.1 - 4.9e-16 58.3 0.9 8.8e-16 57.5 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RKO95613.1 - 8.6e-06 26.1 0.3 5.2e-05 23.6 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 RKO95613.1 - 0.00034 20.7 0.6 0.001 19.1 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RKO95613.1 - 0.0037 17.2 0.1 0.0053 16.7 0.1 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 RKO95613.1 - 0.0037 17.8 0.5 0.0053 17.3 0.5 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 RKO95613.1 - 0.0039 17.5 0.5 0.0072 16.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 RKO95613.1 - 0.014 15.4 1.3 3.3 7.8 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 RKO95613.1 - 0.014 15.6 0.3 0.025 14.8 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Sde2_N_Ubi PF13019.6 RKO95613.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Plexin_cytopl PF08337.12 RKO95613.1 - 0.86 8.2 2.8 6.9 5.2 0.4 2.2 2 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain MFS_1 PF07690.16 RKO95615.1 - 5.3e-12 45.3 12.3 5.3e-12 45.3 12.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF543 PF04418.12 RKO95615.1 - 3 7.9 6.0 38 4.4 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF543) DUF2919 PF11143.8 RKO95615.1 - 5.7 7.3 13.2 0.89 9.9 0.3 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2919) TPR_7 PF13176.6 RKO95616.1 - 2.1e-06 27.3 2.8 0.21 11.7 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKO95616.1 - 4.4e-06 27.1 9.9 0.0037 17.8 1.0 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKO95616.1 - 8.4e-05 22.4 6.1 0.54 10.5 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKO95616.1 - 0.00034 20.8 9.5 0.0059 16.9 0.4 4.6 4 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 RKO95616.1 - 0.00039 20.5 1.6 0.00092 19.3 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKO95616.1 - 0.00042 20.9 4.7 0.012 16.4 0.0 4.8 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKO95616.1 - 0.0015 18.6 1.8 6.1 7.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO95616.1 - 0.0061 17.1 3.8 2.4 9.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 RKO95616.1 - 0.0075 16.6 5.8 8.7 6.8 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 RKO95616.1 - 0.095 13.1 0.2 1.7 9.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKO95616.1 - 0.65 9.9 2.9 4.4 7.3 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAUB PF08164.12 RKO95617.1 - 1.8e-24 86.0 0.1 2.4e-24 85.6 0.1 1.3 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Laminin_G_3 PF13385.6 RKO95619.1 - 2.3e-10 40.8 0.1 3.3e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily TTL PF03133.15 RKO95620.1 - 3.4e-76 256.2 0.1 4e-76 256.0 0.1 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RKO95620.1 - 5e-10 39.1 0.5 0.00024 20.5 0.0 2.4 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RKO95620.1 - 2e-05 24.0 0.0 0.0057 16.0 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp PF02222.22 RKO95620.1 - 0.11 12.1 0.0 0.56 9.8 0.0 2.0 1 1 0 1 1 1 0 ATP-grasp domain Metallophos PF00149.28 RKO95622.1 - 1.2e-29 104.3 0.0 1.4e-29 104.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RIB43A PF05914.12 RKO95623.1 - 6.9e-12 44.8 24.5 7.6e-12 44.7 24.5 1.0 1 0 0 1 1 1 1 RIB43A NRBF2 PF08961.10 RKO95623.1 - 0.23 11.1 8.3 0.28 10.8 8.3 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Stathmin PF00836.19 RKO95623.1 - 8.3 6.4 18.7 10 6.1 18.7 1.1 1 0 0 1 1 1 0 Stathmin family DUF4407 PF14362.6 RKO95623.1 - 8.7 5.6 11.3 9.9 5.4 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NTP_transferase PF00483.23 RKO95625.1 - 3.7e-32 111.9 0.0 4.9e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RKO95625.1 - 1.2e-10 40.7 6.3 3.4e-07 29.7 0.5 4.2 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 RKO95625.1 - 0.012 16.0 0.0 0.022 15.1 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.6 RKO95625.1 - 1.1 9.0 5.4 1 9.2 0.1 3.3 4 0 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase DAGAT PF03982.13 RKO95626.1 - 2.6e-89 299.1 0.0 3e-89 298.9 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase CotJB PF12652.7 RKO95626.1 - 0.0068 16.6 0.7 0.023 14.9 0.5 1.8 2 0 0 2 2 2 1 CotJB protein DUF3605 PF12239.8 RKO95628.1 - 0.078 13.3 0.4 11 6.3 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3605) Myb_DNA-binding PF00249.31 RKO95630.1 - 0.0061 16.7 0.7 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain EF-hand_13 PF17958.1 RKO95631.1 - 5.2e-22 77.5 0.1 1.1e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 RKO95631.1 - 0.0001 22.7 0.1 0.00094 19.6 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain pair PPTA PF01239.22 RKO95633.1 - 8.5e-33 111.1 7.8 1.9e-11 43.3 0.1 4.4 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat OPT PF03169.15 RKO95634.1 - 2.9e-56 191.4 15.9 3.3e-56 191.2 15.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Ribosom_S12_S23 PF00164.25 RKO95635.1 - 1.2e-47 160.2 0.1 1.7e-47 159.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 ArgJ PF01960.18 RKO95636.1 - 6.3e-89 298.3 6.0 6.8e-89 298.2 6.0 1.0 1 0 0 1 1 1 1 ArgJ family Adeno_E4_ORF3 PF06931.11 RKO95636.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Mastadenovirus E4 ORF3 protein DHC_N2 PF08393.13 RKO95637.1 - 2.1e-88 297.1 0.0 2.3e-88 297.0 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 Actin PF00022.19 RKO95639.1 - 5.9e-98 328.1 0.0 2.5e-97 326.1 0.0 1.7 1 1 0 1 1 1 1 Actin A_deamin PF02137.18 RKO95640.1 - 1.8e-18 67.1 0.0 3.4e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain K_channel_TID PF07941.11 RKO95640.1 - 0.033 14.6 0.1 0.033 14.6 0.1 2.3 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain PseudoU_synth_1 PF01416.20 RKO95641.1 - 1.8e-22 79.8 0.0 3.6e-21 75.7 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase Vps26 PF03643.15 RKO95642.1 - 7.2e-32 110.5 0.1 7.8e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 RRM_1 PF00076.22 RKO95643.1 - 9.6e-06 25.3 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPX PF03105.19 RKO95643.1 - 0.0085 16.1 32.1 0.011 15.7 32.1 1.2 1 0 0 1 1 1 1 SPX domain BUD22 PF09073.10 RKO95643.1 - 0.077 12.3 49.0 0.092 12.1 49.0 1.1 1 0 0 1 1 1 0 BUD22 Prothymosin PF03247.14 RKO95643.1 - 0.24 11.9 28.6 0.6 10.6 17.4 2.1 1 1 1 2 2 2 0 Prothymosin/parathymosin family AAA_9 PF12781.7 RKO95644.1 - 1.7e-62 210.4 0.3 2e-62 210.2 0.3 1.1 1 0 0 1 1 1 1 ATP-binding dynein motor region HEAT_2 PF13646.6 RKO95646.1 - 0.035 14.5 0.1 0.084 13.3 0.1 1.7 1 0 0 1 1 1 0 HEAT repeats CLP_protease PF00574.23 RKO95647.1 - 1.3e-34 119.6 0.2 1.6e-34 119.4 0.2 1.0 1 0 0 1 1 1 1 Clp protease SDH_sah PF01972.16 RKO95647.1 - 0.018 14.0 0.0 0.022 13.8 0.0 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase DIOX_N PF14226.6 RKO95648.1 - 7.2e-07 30.0 0.0 8e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal VWA_2 PF13519.6 RKO95649.1 - 0.02 15.6 0.0 0.039 14.6 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain Bromodomain PF00439.25 RKO95650.1 - 4.7e-13 49.0 0.1 5.1e-13 48.9 0.1 1.0 1 0 0 1 1 1 1 Bromodomain TonB_N PF16031.5 RKO95651.1 - 1.3 9.5 32.7 0.11 13.0 24.5 2.1 2 0 0 2 2 2 0 TonB polyproline region HSP20 PF00011.21 RKO95652.1 - 2e-07 31.1 0.0 4.9e-05 23.4 0.0 2.2 1 1 0 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.16 RKO95652.1 - 0.086 13.9 0.0 0.1 13.6 0.0 1.5 1 1 0 1 1 1 0 CS domain ECH_1 PF00378.20 RKO95654.1 - 9.3e-25 87.4 0.0 1.8e-24 86.4 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 RKO95654.1 - 6.5e-06 25.9 0.0 8.3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase SNF2_N PF00176.23 RKO95655.1 - 3e-64 216.9 0.6 4e-64 216.5 0.6 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 RKO95655.1 - 1.5e-08 34.8 0.0 2.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 RKO95655.1 - 0.001 18.9 0.0 0.002 17.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4020 PF13212.6 RKO95655.1 - 0.085 12.7 0.2 0.14 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) SDA1 PF05285.12 RKO95656.1 - 0.42 10.0 13.4 0.46 9.9 13.4 1.0 1 0 0 1 1 1 0 SDA1 Endosulfine PF04667.17 RKO95657.1 - 1.6e-18 66.6 0.6 2.4e-18 66.0 0.4 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Proteasome PF00227.26 RKO95660.1 - 4.3e-06 26.3 0.2 5.7e-06 25.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit DinB_2 PF12867.7 RKO95661.1 - 0.12 12.9 0.1 0.77 10.3 0.0 2.0 2 0 0 2 2 2 0 DinB superfamily TctC PF03401.14 RKO95661.1 - 0.19 10.7 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor PhoLip_ATPase_C PF16212.5 RKO95662.1 - 3e-17 63.2 12.0 3.4e-17 63.0 12.0 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal AA_permease_C PF13906.6 RKO95662.1 - 4.2 7.5 11.6 0.41 10.8 3.6 2.7 3 0 0 3 3 3 0 C-terminus of AA_permease AhpC-TSA PF00578.21 RKO95664.1 - 1.4e-30 105.7 0.0 1.9e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKO95664.1 - 1.6e-13 50.6 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RKO95664.1 - 5.4e-07 29.3 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GSHPx PF00255.19 RKO95664.1 - 0.25 10.9 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Glutathione peroxidase PGP_phosphatase PF09419.10 RKO95665.1 - 8.6e-37 126.3 0.0 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 RKO95665.1 - 2.3e-07 30.8 0.1 4.8e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 HAD-hyrolase-like Glyco_transf_5 PF08323.11 RKO95665.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.4 1 1 0 1 1 1 0 Starch synthase catalytic domain HAD_2 PF13419.6 RKO95665.1 - 0.095 12.8 0.2 0.19 11.8 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RKO95665.1 - 0.17 12.1 0.0 0.57 10.4 0.0 1.6 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Fes1 PF08609.10 RKO95667.1 - 3.8e-11 43.7 5.1 6.9e-11 42.9 4.5 1.7 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm_2 PF04826.13 RKO95667.1 - 0.02 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 Armadillo-like DUF4704 PF15787.5 RKO95667.1 - 0.093 12.0 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) NYN PF01936.18 RKO95668.1 - 0.00017 22.1 0.0 0.16 12.4 0.0 2.1 2 0 0 2 2 2 2 NYN domain IQCJ-SCHIP1 PF15157.6 RKO95668.1 - 0.34 10.7 4.2 0.48 10.2 4.2 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif RasGAP PF00616.19 RKO95669.1 - 1.5e-20 73.8 0.0 1.3e-18 67.5 0.0 2.1 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 RKO95669.1 - 5.9e-10 39.4 0.0 9.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain Plexin_cytopl PF08337.12 RKO95669.1 - 0.0023 16.7 0.2 0.8 8.3 0.0 2.1 2 0 0 2 2 2 2 Plexin cytoplasmic RasGAP domain PDEase_I PF00233.19 RKO95670.1 - 1.1e-33 116.9 0.1 1.4e-33 116.6 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 RKO95670.1 - 0.0066 16.7 0.1 0.01 16.1 0.1 1.3 1 0 0 1 1 1 1 HD domain LegC3_N PF18654.1 RKO95671.1 - 0.046 13.0 1.1 2.1 7.5 0.1 2.1 2 0 0 2 2 2 0 LegC3 N-terminal coiled-coil domain T3SS_needle_E PF08988.10 RKO95671.1 - 0.24 11.6 6.1 5.2 7.3 0.6 2.5 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle LSM PF01423.22 RKO95672.1 - 1.6e-14 53.3 0.0 2.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKO95672.1 - 0.00045 20.3 0.0 0.00065 19.8 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 RKO95672.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain OPT PF03169.15 RKO95673.1 - 0.0079 14.9 1.8 0.0089 14.7 1.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AAA_11 PF13086.6 RKO95675.1 - 8.7e-11 42.1 0.0 9.2e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO95675.1 - 2.8e-08 34.2 0.0 2.9e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO95675.1 - 3e-05 23.8 0.0 3.2e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 RKO95675.1 - 0.0024 17.5 0.0 0.0026 17.4 0.0 1.0 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_25 PF13481.6 RKO95675.1 - 0.0065 16.1 0.0 0.0065 16.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKO95675.1 - 0.0068 16.7 0.0 0.0071 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 RKO95675.1 - 0.01 16.2 0.4 0.11 12.9 0.4 1.9 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RKO95675.1 - 0.016 15.6 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 RKO95675.1 - 0.021 14.5 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 RKO95675.1 - 0.026 14.0 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 RKO95675.1 - 0.034 14.5 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 RKO95675.1 - 0.039 13.2 0.0 0.041 13.1 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 RKO95675.1 - 0.049 13.6 0.0 0.049 13.6 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_5 PF07728.14 RKO95675.1 - 0.067 13.2 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 RKO95675.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 RKO95675.1 - 0.2 12.2 0.0 0.23 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.17 RKO95675.1 - 0.24 10.2 0.0 0.24 10.2 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DUF4874 PF16173.5 RKO95676.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) DUF4832 PF16116.5 RKO95676.1 - 0.056 13.3 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) SURF2 PF05477.11 RKO95677.1 - 2.3 7.8 6.6 3.3 7.4 6.6 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Aa_trans PF01490.18 RKO95678.1 - 8.7e-10 37.9 3.9 8.7e-10 37.9 3.9 2.0 3 0 0 3 3 3 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RKO95678.1 - 1.6e-06 27.4 1.7 1.6e-06 27.4 1.7 2.3 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Syja_N PF02383.18 RKO95679.1 - 5e-81 272.5 0.0 5.8e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 SacI homology domain FapA PF03961.13 RKO95680.1 - 0.074 11.6 0.1 0.074 11.6 0.1 3.0 2 1 1 3 3 3 0 Flagellar Assembly Protein A bZIP_1 PF00170.21 RKO95680.1 - 0.9 9.7 12.1 17 5.6 1.7 4.8 5 0 0 5 5 5 0 bZIP transcription factor NYD-SP28_assoc PF14775.6 RKO95680.1 - 1.2 9.3 7.5 45 4.2 0.2 4.2 4 0 0 4 4 4 0 Sperm tail C-terminal domain YabA PF06156.13 RKO95680.1 - 2.6 8.7 20.7 6 7.6 3.3 4.5 4 2 0 4 4 4 0 Initiation control protein YabA DUF2730 PF10805.8 RKO95680.1 - 4.8 7.3 9.1 1.6 8.8 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Leu_zip PF15294.6 RKO95680.1 - 7.5 6.0 30.4 0.25 10.8 3.0 3.7 2 1 2 4 4 4 0 Leucine zipper Peptidase_S9 PF00326.21 RKO95681.1 - 1.4e-15 57.3 0.4 2e-15 56.9 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 RKO95681.1 - 0.012 15.1 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase DLH PF01738.18 RKO95681.1 - 0.053 13.1 0.1 0.086 12.4 0.1 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family FliL PF03748.14 RKO95681.1 - 0.066 13.8 0.0 0.078 13.6 0.0 1.2 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Hydrophobin PF01185.18 RKO95682.1 - 1.2e-07 32.2 7.1 1.5e-07 31.9 7.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin RskA PF10099.9 RKO95684.1 - 0.57 10.5 12.1 0.56 10.5 12.1 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DCP2 PF05026.13 RKO95685.1 - 7.3e-26 90.3 3.2 1.1e-25 89.8 3.2 1.2 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 RKO95685.1 - 1e-14 54.7 0.0 1.6e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 RKO95685.1 - 0.084 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain 2OG-Fe_Oxy_2 PF10014.9 RKO95685.1 - 0.16 11.8 0.2 0.53 10.1 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe dioxygenase DUF1929 PF09118.11 RKO95686.1 - 1.3e-17 63.9 0.3 1.4e-17 63.8 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) SP_C-Propep PF08999.10 RKO95686.1 - 0.022 14.5 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Sec23_helical PF04815.15 RKO95687.1 - 1.2e-25 89.3 0.3 2e-25 88.6 0.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 RKO95687.1 - 1.2e-13 51.6 0.0 2.2e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.15 RKO95687.1 - 3e-10 40.1 0.0 4.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Gelsolin PF00626.22 RKO95687.1 - 1.8e-05 24.5 0.0 5.8e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Snf7 PF03357.21 RKO95690.1 - 3.1e-11 43.2 19.6 3.1e-11 43.2 19.6 1.6 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 RKO95690.1 - 0.00014 21.8 6.2 0.00021 21.2 6.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DMSP_lyase PF16867.5 RKO95690.1 - 0.0024 17.6 1.2 0.0029 17.3 0.2 1.6 2 0 0 2 2 2 1 Dimethlysulfonioproprionate lyase Big_2 PF02368.18 RKO95690.1 - 0.12 12.3 2.6 0.1 12.5 0.5 2.0 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) DUF5601 PF18151.1 RKO95690.1 - 0.48 10.8 3.6 1.3 9.3 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5601) YlqD PF11068.8 RKO95690.1 - 5.6 7.4 18.0 2.5 8.5 2.1 2.5 2 1 1 3 3 3 0 YlqD protein EF-hand_1 PF00036.32 RKO95691.1 - 1.1e-15 55.9 0.7 2.6e-09 35.9 0.2 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 RKO95691.1 - 4.6e-14 51.1 0.4 1.9e-08 33.5 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 RKO95691.1 - 2.1e-13 50.5 0.4 2.7e-13 50.2 0.4 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 RKO95691.1 - 9.7e-08 31.2 0.4 2.7e-05 23.5 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 RKO95691.1 - 1.2e-07 31.4 1.7 0.00084 19.1 0.2 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 RKO95691.1 - 7.2e-05 22.7 0.1 0.00021 21.2 0.1 1.6 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 RKO95691.1 - 0.00044 20.5 0.0 0.0006 20.1 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain Caleosin PF05042.13 RKO95691.1 - 0.034 14.1 0.0 0.082 12.8 0.0 1.6 1 1 1 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 RKO95691.1 - 0.12 12.7 0.2 0.17 12.2 0.2 1.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Myticin-prepro PF10690.9 RKO95692.1 - 0.5 10.7 7.6 3.5 7.9 0.4 2.3 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel tRNA_U5-meth_tr PF05958.11 RKO95693.1 - 0.00017 20.7 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Cullin_Nedd8 PF10557.9 RKO95694.1 - 3.1e-20 72.0 0.0 3.8e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Cullin protein neddylation domain peroxidase PF00141.23 RKO95695.1 - 1.2e-33 116.7 0.0 1.7e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ENTH PF01417.20 RKO95696.1 - 4.9e-39 133.2 0.0 5.5e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 RKO95696.1 - 0.0047 15.9 0.0 0.0047 15.9 0.0 1.1 1 0 0 1 1 1 1 ANTH domain Death PF00531.22 RKO95700.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.3 1 0 0 1 1 1 0 Death domain CAP_N PF01213.19 RKO95700.1 - 6.3 6.2 7.4 0.18 11.2 1.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NT-C2 PF10358.9 RKO95701.1 - 5e-25 87.9 0.0 6.1e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins XPG_I PF00867.18 RKO95703.1 - 4.1e-13 49.5 0.0 7.5e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region Phi29_Phage_SSB PF17427.2 RKO95703.1 - 0.16 12.2 0.6 4.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Phage Single-stranded DNA-binding protein tRNA-synt_1c_C PF03950.18 RKO95704.1 - 4.1e-20 72.4 0.3 6.9e-20 71.6 0.3 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_bind PF01588.20 RKO95704.1 - 0.069 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative tRNA binding domain Ribosomal_60s PF00428.19 RKO95704.1 - 0.3 11.7 20.3 0.089 13.4 8.7 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SelP_N PF04592.14 RKO95706.1 - 4.2 6.7 15.9 6 6.2 15.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ILVD_EDD PF00920.21 RKO95707.1 - 1.8e-28 99.5 0.0 2.3e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Dehydratase family Cyt-b5 PF00173.28 RKO95708.1 - 2.8e-05 24.2 0.0 4.9e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Carn_acyltransf PF00755.20 RKO95709.1 - 9.6e-92 308.5 0.0 1.1e-91 308.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_M15_4 PF13539.6 RKO95709.1 - 0.078 13.5 0.0 0.51 10.9 0.0 2.2 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase TipAS PF07739.13 RKO95709.1 - 0.13 12.8 1.0 4.3 7.9 0.0 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain zf-CCCH PF00642.24 RKO95710.1 - 8.5e-19 67.0 16.6 1.1e-13 50.7 2.6 2.1 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RKO95710.1 - 1.6e-10 40.7 14.4 1.7e-07 31.0 4.3 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 RKO95710.1 - 7.7e-06 25.6 1.0 7.7e-06 25.6 1.0 2.4 2 1 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 RKO95710.1 - 0.0093 16.4 0.6 0.0093 16.4 0.6 2.7 3 1 0 3 3 3 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 RKO95710.1 - 0.027 15.2 10.9 0.69 10.6 2.7 2.0 1 1 1 2 2 2 0 Torus domain oligo_HPY PF08352.12 RKO95710.1 - 4 8.0 10.8 2.4 8.7 2.6 2.1 1 1 1 2 2 2 0 Oligopeptide/dipeptide transporter, C-terminal region zf-C2H2_4 PF13894.6 RKO95711.1 - 1.1e-05 25.8 11.9 0.0019 18.9 1.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKO95711.1 - 3.3e-05 24.1 13.0 0.00025 21.3 1.6 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKO95711.1 - 3.6e-05 24.0 13.7 0.038 14.4 1.2 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RKO95711.1 - 0.00046 20.1 6.3 2 8.5 0.0 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 RKO95711.1 - 0.00069 19.9 1.3 0.12 12.8 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HE PF16278.5 RKO95711.1 - 0.019 15.4 5.9 1.2 9.6 0.1 3.0 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 RKO95711.1 - 0.04 13.7 3.5 0.64 9.8 0.1 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type Actin_micro PF17003.5 RKO95711.1 - 0.082 12.1 2.0 0.084 12.0 2.0 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_jaz PF12171.8 RKO95711.1 - 0.33 11.3 0.5 0.33 11.3 0.5 2.9 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Vps39_2 PF10367.9 RKO95711.1 - 0.34 11.4 3.3 3.3 8.2 3.1 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Zn-ribbon_8 PF09723.10 RKO95711.1 - 1.2 9.3 7.2 0.48 10.6 3.9 2.1 2 1 0 2 2 2 0 Zinc ribbon domain Defensin_5 PF18251.1 RKO95711.1 - 3.6 7.7 8.2 14 5.8 2.0 2.2 2 0 0 2 2 2 0 Fungal defensin Copsin MBOAT_2 PF13813.6 RKO95712.1 - 3.7e-13 49.5 4.7 9.1e-13 48.3 4.7 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Glycos_transf_2 PF00535.26 RKO95714.1 - 2e-26 92.8 0.0 2.7e-26 92.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 RKO95714.1 - 7e-10 39.2 0.0 9.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 RKO95714.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 mRNA_cap_C PF03919.15 RKO95715.1 - 2.6e-17 63.4 0.2 4.6e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain mRNA_cap_enzyme PF01331.19 RKO95715.1 - 1.6e-15 57.4 0.1 2.7e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_A_M PF01068.21 RKO95715.1 - 8.7e-05 22.3 0.0 0.00017 21.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain Hydrophobin PF01185.18 RKO95717.1 - 1.5e-07 32.0 9.6 2.1e-07 31.5 9.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_29 PF08116.11 RKO95717.1 - 0.011 15.7 0.3 0.011 15.7 0.3 2.1 2 1 0 2 2 2 0 PhTx neurotoxin family PQQ_2 PF13360.6 RKO95718.1 - 0.086 12.4 0.0 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 PQQ-like domain CDC50 PF03381.15 RKO95723.1 - 5e-62 209.9 0.0 5.9e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family zf-HC3 PF16827.5 RKO95723.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 zinc-finger FAM194 PF14977.6 RKO95723.1 - 0.15 11.3 0.0 18 4.5 0.0 3.0 3 0 0 3 3 3 0 FAM194 protein Anoctamin PF04547.12 RKO95724.1 - 6.1e-18 64.9 0.8 8.2e-18 64.5 0.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF3561 PF12084.8 RKO95724.1 - 0.28 11.2 2.6 0.56 10.2 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) MMM1 PF10296.9 RKO95725.1 - 9e-08 31.5 0.1 0.00041 19.5 0.0 2.0 2 0 0 2 2 2 2 Maintenance of mitochondrial morphology protein 1 bZIP_1 PF00170.21 RKO95726.1 - 2.3e-05 24.4 7.4 0.039 14.0 0.0 3.4 2 1 2 4 4 4 2 bZIP transcription factor TPR_MLP1_2 PF07926.12 RKO95726.1 - 0.00059 19.9 5.1 0.002 18.2 4.9 1.8 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein bZIP_2 PF07716.15 RKO95726.1 - 0.001 19.1 6.9 0.22 11.7 0.1 2.8 3 1 0 3 3 3 2 Basic region leucine zipper ERM PF00769.19 RKO95726.1 - 0.0015 18.4 0.4 0.002 18.0 0.4 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family MIP-T3_C PF17749.1 RKO95726.1 - 0.003 17.5 1.9 0.0043 17.0 1.9 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 C-terminal region DUF3496 PF12001.8 RKO95726.1 - 0.0046 17.3 4.9 0.0073 16.7 4.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3496) MAD PF05557.13 RKO95726.1 - 0.005 15.3 4.2 0.0066 14.9 4.2 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein FH2 PF02181.23 RKO95726.1 - 0.011 14.9 1.9 0.014 14.6 1.9 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain HAP1_N PF04849.13 RKO95726.1 - 0.011 15.0 9.2 0.064 12.5 3.0 2.1 1 1 1 2 2 2 0 HAP1 N-terminal conserved region Filament PF00038.21 RKO95726.1 - 0.013 15.1 5.5 0.71 9.4 0.9 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF16 PF01519.16 RKO95726.1 - 0.024 15.1 4.3 0.024 15.1 0.7 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4164 PF13747.6 RKO95726.1 - 0.027 14.7 1.5 0.027 14.7 1.5 1.8 2 1 0 2 2 1 0 Domain of unknown function (DUF4164) DivIC PF04977.15 RKO95726.1 - 0.03 14.1 1.8 4.2 7.2 0.1 3.0 2 1 1 3 3 3 0 Septum formation initiator BCAS2 PF05700.11 RKO95726.1 - 0.031 14.0 0.8 0.049 13.3 0.8 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) YabA PF06156.13 RKO95726.1 - 0.032 14.9 2.9 3.4 8.4 0.1 2.6 1 1 2 3 3 3 0 Initiation control protein YabA Cnn_1N PF07989.11 RKO95726.1 - 0.038 14.2 6.4 1.2 9.3 0.7 2.5 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Bacillus_HBL PF05791.11 RKO95726.1 - 0.051 13.4 0.9 0.076 12.8 0.9 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) K-box PF01486.17 RKO95726.1 - 0.052 13.7 8.0 0.11 12.7 5.6 2.0 1 1 1 2 2 2 0 K-box region CENP-F_leu_zip PF10473.9 RKO95726.1 - 0.07 13.2 9.2 0.14 12.2 9.2 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 RKO95726.1 - 0.11 11.8 7.5 0.83 9.0 7.5 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 RKO95726.1 - 0.13 12.4 1.8 0.2 11.7 1.4 1.5 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 YscO PF07321.12 RKO95726.1 - 0.16 11.9 5.2 0.097 12.6 0.9 2.0 1 1 1 2 2 2 0 Type III secretion protein YscO DUF3450 PF11932.8 RKO95726.1 - 0.18 11.1 2.5 8.1 5.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CEP63 PF17045.5 RKO95726.1 - 0.19 11.6 7.2 0.97 9.3 7.2 1.8 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa DUF4201 PF13870.6 RKO95726.1 - 0.21 11.3 6.4 0.3 10.8 5.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 RKO95726.1 - 0.21 10.4 6.6 0.27 10.1 6.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein WD40_alt PF14077.6 RKO95726.1 - 0.22 11.4 2.4 2.5 8.1 0.0 3.0 2 1 0 3 3 3 0 Alternative WD40 repeat motif KELK PF15796.5 RKO95726.1 - 0.27 11.7 7.8 0.18 12.3 5.4 2.0 2 1 0 2 2 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Rx_N PF18052.1 RKO95726.1 - 0.33 11.2 3.9 0.43 10.9 1.2 2.5 1 1 2 3 3 3 0 Rx N-terminal domain PRKG1_interact PF15898.5 RKO95726.1 - 0.49 11.3 6.9 2 9.3 6.9 1.9 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 RKO95726.1 - 0.76 10.3 5.3 9.1 6.8 0.8 3.1 1 1 1 2 2 2 0 Cell division protein ZapB JIP_LZII PF16471.5 RKO95726.1 - 1.3 9.2 8.2 15 5.9 0.0 3.2 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 RKO95726.1 - 1.9 9.0 7.1 7.5 7.1 0.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 RKO95726.1 - 2 8.6 10.3 0.28 11.4 6.0 1.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DMPK_coil PF08826.10 RKO95726.1 - 5.9 7.1 7.0 6.2 7.0 0.2 3.0 2 1 1 3 3 3 0 DMPK coiled coil domain like Ribosomal_L17 PF01196.19 RKO95727.1 - 4.8e-20 72.3 0.1 6.1e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Pkinase PF00069.25 RKO95729.1 - 5.4e-61 206.3 0.0 6.3e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95729.1 - 1.2e-45 155.9 0.0 1.4e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO95729.1 - 7.3e-05 21.7 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RKO95729.1 - 0.017 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like VWA_2 PF13519.6 RKO95730.1 - 1.1e-24 87.2 0.2 4.1e-24 85.3 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 RKO95730.1 - 9.3e-07 28.8 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like DUF4362 PF14275.6 RKO95730.1 - 0.047 14.0 0.5 3.2 8.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4362) EAL PF00563.20 RKO95730.1 - 0.084 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 EAL domain AKAP7_RIRII_bdg PF10470.9 RKO95730.1 - 0.25 11.4 0.3 0.25 11.4 0.3 1.7 2 0 0 2 2 2 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein AAA PF00004.29 RKO95732.1 - 1.3e-42 145.3 0.0 2.4e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO95732.1 - 1e-07 31.6 0.0 2.9e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RKO95732.1 - 8.8e-06 26.2 0.1 0.00011 22.6 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 RKO95732.1 - 1.7e-05 24.6 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 RKO95732.1 - 2.9e-05 23.9 0.0 5.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RKO95732.1 - 4.1e-05 23.6 0.0 0.0002 21.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 RKO95732.1 - 4.6e-05 22.8 0.3 9.6e-05 21.7 0.0 1.6 2 1 0 2 2 1 1 TIP49 P-loop domain AAA_14 PF13173.6 RKO95732.1 - 5.6e-05 23.2 0.0 0.00037 20.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKO95732.1 - 9.6e-05 22.7 0.1 0.023 14.9 0.0 2.5 1 1 1 2 2 2 1 AAA domain MIT PF04212.18 RKO95732.1 - 0.00012 22.1 2.3 0.00033 20.7 2.3 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RNA_helicase PF00910.22 RKO95732.1 - 0.00014 22.2 0.1 0.0055 17.1 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.13 RKO95732.1 - 0.00039 19.6 0.0 0.00074 18.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 RKO95732.1 - 0.0023 18.1 0.0 0.0077 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 RKO95732.1 - 0.0036 17.4 0.0 0.0099 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 RKO95732.1 - 0.0037 17.0 0.4 0.0098 15.6 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 RKO95732.1 - 0.005 17.4 0.0 0.016 15.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 RKO95732.1 - 0.0052 16.7 0.0 0.24 11.3 0.0 2.5 1 1 1 2 2 2 1 NACHT domain ATPase PF06745.13 RKO95732.1 - 0.0086 15.4 0.1 3.3 7.0 0.0 2.3 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.6 RKO95732.1 - 0.0092 15.6 0.1 0.17 11.4 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 RKO95732.1 - 0.013 16.0 0.0 0.044 14.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RKO95732.1 - 0.022 14.2 0.0 0.059 12.8 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 RKO95732.1 - 0.031 14.0 0.0 0.34 10.6 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 RKO95732.1 - 0.042 13.3 0.1 0.086 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.17 RKO95732.1 - 0.054 12.6 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 RKO95732.1 - 0.06 12.9 0.0 0.25 10.8 0.0 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 RKO95732.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TniB PF05621.11 RKO95732.1 - 0.11 11.8 0.0 17 4.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein Sigma54_activ_2 PF14532.6 RKO95732.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 RKO95732.1 - 0.15 12.2 0.1 0.42 10.7 0.0 1.8 2 0 0 2 2 2 0 Torsin Smr PF01713.21 RKO95732.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 Smr domain BRCA-2_OB1 PF09103.10 RKO95733.1 - 1.9e-17 63.4 0.0 2.6e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 RKO95733.1 - 7.7e-05 22.4 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 BRCA2, helical Rep-A_N PF04057.12 RKO95733.1 - 0.052 13.6 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain S10_plectin PF03501.15 RKO95734.1 - 9.2e-30 102.6 0.0 1e-29 102.4 0.0 1.0 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 RKO95734.1 - 0.1 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_22 PF13309.6 RKO95734.1 - 0.14 12.3 0.0 15 5.8 0.0 2.1 1 1 1 2 2 2 0 HTH domain PhoLip_ATPase_C PF16212.5 RKO95736.1 - 2.5e-52 178.1 11.0 2.8e-52 178.0 11.0 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase_3 PF08282.12 RKO95736.1 - 0.0013 18.6 0.3 0.0019 18.0 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RasGAP PF00616.19 RKO95737.1 - 4.5e-35 121.2 0.0 5e-19 68.8 0.0 2.3 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase RRM_1 PF00076.22 RKO95738.1 - 1.3e-13 50.6 0.0 1.8e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 RKO95738.1 - 0.0013 18.7 0.2 0.0016 18.4 0.2 1.2 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 RKO95738.1 - 0.0062 16.5 0.0 0.0095 15.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 RKO95738.1 - 0.0088 16.2 0.0 0.029 14.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif Lipoprotein_1 PF00820.19 RKO95738.1 - 0.046 12.8 0.1 0.051 12.6 0.1 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein Peptidase_S8 PF00082.22 RKO95739.1 - 3.4e-16 59.4 0.2 3.7e-16 59.2 0.2 1.1 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 RKO95739.1 - 6.2e-05 22.9 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 PA domain RMI1_N PF08585.12 RKO95740.1 - 1.5e-24 87.0 0.0 2.3e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 RecQ mediated genome instability protein PBC PF03792.13 RKO95740.1 - 0.47 10.2 5.4 0.32 10.8 3.5 1.6 2 0 0 2 2 2 0 PBC domain DUF1993 PF09351.10 RKO95740.1 - 0.48 10.5 2.6 0.83 9.8 2.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1993) BLOC1_2 PF10046.9 RKO95743.1 - 0.02 15.2 4.7 2 8.8 0.7 3.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spectrin PF00435.21 RKO95743.1 - 0.03 14.8 8.5 0.091 13.3 5.2 2.7 3 0 0 3 3 3 0 Spectrin repeat KxDL PF10241.9 RKO95743.1 - 0.55 10.5 8.0 13 6.2 0.2 3.8 4 0 0 4 4 4 0 Uncharacterized conserved protein COG5 PF10392.9 RKO95743.1 - 0.83 9.8 7.4 2.6 8.2 0.3 3.1 4 0 0 4 4 4 0 Golgi transport complex subunit 5 MerR-DNA-bind PF09278.11 RKO95743.1 - 2.6 8.7 4.3 5 7.7 0.2 3.0 2 1 1 3 3 3 0 MerR, DNA binding DUF1664 PF07889.12 RKO95743.1 - 5 7.2 10.9 7.4 6.6 2.7 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Hydrolase_like PF13242.6 RKO95745.1 - 3.8e-18 65.3 0.1 7.4e-18 64.4 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RKO95745.1 - 1.1e-11 44.7 0.0 2e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase RecO_N_2 PF13114.6 RKO95745.1 - 0.12 12.1 0.2 1.6 8.5 0.0 2.1 2 0 0 2 2 2 0 RecO N terminal RVP_2 PF08284.11 RKO95746.1 - 0.0058 16.4 0.1 0.0067 16.2 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Sld5 PF05916.11 RKO95747.1 - 3.3e-14 53.2 0.0 4.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Fibrillarin PF01269.17 RKO95748.1 - 5.3e-100 333.2 0.0 5.9e-100 333.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 RKO95748.1 - 9.3e-06 25.5 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 RKO95748.1 - 0.0031 17.3 0.0 0.0056 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 RKO95748.1 - 0.0081 16.3 0.0 0.0091 16.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 RKO95748.1 - 0.07 12.8 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RNA_pol_Rpb2_6 PF00562.28 RKO95749.1 - 3.4e-65 220.6 0.1 3.8e-65 220.4 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 PX PF00787.24 RKO95750.1 - 3.3e-06 27.1 0.0 3.6e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 PX domain Pyr_redox_2 PF07992.14 RKO95751.1 - 1.1e-13 51.1 0.0 1.4e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO95751.1 - 2.9e-12 47.0 0.0 5.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKO95751.1 - 0.052 12.8 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RKO95751.1 - 0.076 12.1 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NOB1_Zn_bind PF08772.11 RKO95753.1 - 1.9e-26 92.0 0.2 3.3e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like DUF2072 PF09845.9 RKO95753.1 - 0.039 14.2 0.5 0.073 13.3 0.5 1.4 1 1 0 1 1 1 0 Zn-ribbon containing protein DZR PF12773.7 RKO95753.1 - 0.056 13.5 0.3 0.094 12.8 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon PcfJ PF14284.6 RKO95753.1 - 0.066 13.1 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 PcfJ-like protein HypA PF01155.19 RKO95753.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-NADH-PPase PF09297.11 RKO95753.1 - 0.68 9.6 5.5 0.78 9.4 0.9 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Peptidase_M41 PF01434.18 RKO95754.1 - 3.8e-45 154.1 0.0 5.7e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 RKO95754.1 - 1.2e-43 148.7 0.0 2e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO95754.1 - 1.1e-11 44.3 0.2 2.3e-11 43.3 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKO95754.1 - 0.00097 19.1 0.1 0.0052 16.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO95754.1 - 0.0011 19.4 1.8 0.091 13.1 0.2 3.1 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 RKO95754.1 - 0.0011 18.7 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RKO95754.1 - 0.0021 18.4 0.3 0.35 11.1 0.1 2.9 2 1 0 3 3 3 1 AAA domain TIP49 PF06068.13 RKO95754.1 - 0.0021 17.3 0.0 0.0035 16.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 RKO95754.1 - 0.004 17.3 0.0 0.016 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 RKO95754.1 - 0.01 16.3 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RKO95754.1 - 0.026 14.3 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 RKO95754.1 - 0.034 13.5 0.4 0.21 11.0 0.2 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RKO95754.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 RKO95754.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ldi PF18566.1 RKO95754.1 - 0.21 11.0 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Linalool dehydratase/isomerase MMS1_N PF10433.9 RKO95755.1 - 1.7e-08 33.5 0.0 5.2e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PXA PF02194.15 RKO95755.1 - 9.1e-08 32.3 0.0 1.6e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 PXA domain DnaJ_C PF01556.18 RKO95756.1 - 5e-27 94.8 0.0 6.5e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RKO95756.1 - 5.5e-24 84.1 4.1 7.5e-24 83.6 4.1 1.2 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RKO95756.1 - 7.1e-10 39.1 17.3 1.1e-09 38.4 17.3 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 RKO95756.1 - 4.3 7.4 7.5 12 6.0 0.7 2.2 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 RKO95756.1 - 5.6 7.1 9.5 4.3 7.4 0.6 2.3 2 0 0 2 2 2 0 Double zinc ribbon EIF_2_alpha PF07541.12 RKO95758.1 - 1.1e-38 131.9 0.1 2.9e-38 130.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 RKO95758.1 - 3.6e-14 52.8 0.6 7.4e-14 51.8 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 RKO95758.1 - 0.0033 16.8 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family PQ-loop PF04193.14 RKO95759.1 - 5e-06 26.2 0.5 5e-06 26.2 0.5 1.6 2 0 0 2 2 2 1 PQ loop repeat Adeno_GP19K PF04881.13 RKO95759.1 - 0.2 11.6 1.4 0.21 11.6 0.5 1.5 2 0 0 2 2 2 0 Adenovirus GP19K DUF2457 PF10446.9 RKO95759.1 - 1.8 7.6 10.5 2.2 7.3 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Brr6_like_C_C PF10104.9 RKO95760.1 - 0.022 14.6 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Mito_fiss_reg PF05308.11 RKO95760.1 - 8.3 6.4 6.1 11 6.0 6.1 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Glutaredoxin PF00462.24 RKO95762.1 - 2.7e-38 130.0 0.0 1.1e-18 67.2 0.0 3.4 4 0 0 4 4 4 2 Glutaredoxin SH3BGR PF04908.15 RKO95762.1 - 9.9e-07 28.9 0.0 0.00054 20.1 0.0 3.3 3 0 0 3 3 3 1 SH3-binding, glutamic acid-rich protein HyaE PF07449.11 RKO95762.1 - 2.1e-05 24.4 0.3 0.014 15.3 0.0 3.2 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin PF00085.20 RKO95762.1 - 0.0093 15.9 0.0 0.074 13.0 0.0 2.3 1 1 0 2 2 2 1 Thioredoxin CNOT1_HEAT_N PF16419.5 RKO95762.1 - 0.03 14.0 0.0 0.72 9.5 0.0 2.3 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 1 HEAT repeat LEM PF03020.15 RKO95762.1 - 0.082 12.5 0.0 0.71 9.5 0.0 2.5 2 0 0 2 2 2 0 LEM domain DNA_processg_A PF02481.15 RKO95762.1 - 0.14 11.4 0.0 0.49 9.6 0.0 1.8 2 0 0 2 2 2 0 DNA recombination-mediator protein A Thioredoxin_2 PF13098.6 RKO95762.1 - 0.17 12.3 0.1 4.4 7.8 0.0 2.9 2 1 1 3 3 3 0 Thioredoxin-like domain TFIIA PF03153.13 RKO95763.1 - 0.026 14.5 10.9 0.031 14.3 10.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S14 PF00253.21 RKO95764.1 - 9.2e-19 67.0 0.0 1.4e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Myosin_head PF00063.21 RKO95765.1 - 2.3e-26 92.2 0.0 2.5e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 RKO95765.1 - 0.01 16.2 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Fanconi_A PF03511.14 RKO95765.1 - 0.1 12.6 0.1 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Fanconi anaemia group A protein Torsin PF06309.11 RKO95765.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Torsin MMS19_N PF14500.6 RKO95769.1 - 1.4e-62 211.7 0.0 1.9e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.6 RKO95769.1 - 0.07 13.5 1.1 2 8.9 0.0 3.0 2 1 0 2 2 2 0 HEAT repeats STAG PF08514.11 RKO95770.1 - 9.6e-11 41.6 0.0 1.9e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 STAG domain CsbD PF05532.12 RKO95771.1 - 4.8e-09 36.0 8.2 6.4e-09 35.6 7.0 1.7 2 0 0 2 2 2 1 CsbD-like ATP-synt_B PF00430.18 RKO95771.1 - 0.3 11.2 5.7 0.4 10.8 5.7 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) TMEM247 PF15444.6 RKO95772.1 - 0.058 13.4 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Adeno_terminal PF02459.15 RKO95772.1 - 0.1 10.9 2.3 0.13 10.7 2.3 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein RNA_pol_Rpb1_3 PF04983.18 RKO95774.1 - 1.5e-30 106.2 0.0 2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RKO95774.1 - 1.4e-19 70.0 0.0 2.2e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TRAM PF01938.20 RKO95774.1 - 0.13 12.2 0.0 0.78 9.8 0.0 2.2 3 0 0 3 3 3 0 TRAM domain Ribosom_S12_S23 PF00164.25 RKO95775.1 - 2e-36 124.1 2.4 2.3e-36 123.8 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 RKO95775.1 - 0.0032 18.2 0.0 0.0059 17.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S12 RAP1 PF07218.11 RKO95777.1 - 0.061 11.6 4.6 0.089 11.1 4.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pheromone PF08015.11 RKO95777.1 - 1.8 9.7 8.0 1.1 10.4 2.4 2.8 2 0 0 2 2 2 0 Fungal mating-type pheromone FTR1 PF03239.14 RKO95778.1 - 6.7e-19 68.2 9.7 1.8e-18 66.8 8.1 1.9 2 0 0 2 2 2 1 Iron permease FTR1 family DUF3180 PF11377.8 RKO95778.1 - 1.6 8.9 13.9 3.8 7.7 13.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) Methyltransf_11 PF08241.12 RKO95781.1 - 4.7e-12 46.4 0.0 6.6e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO95781.1 - 1.5e-10 41.6 0.0 2.3e-10 41.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO95781.1 - 3.5e-05 23.6 0.0 5.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RKO95781.1 - 0.0011 18.5 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 RKO95781.1 - 0.0014 18.0 0.0 0.0019 17.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RKO95781.1 - 0.0026 18.4 0.0 0.0038 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO95781.1 - 0.0063 16.4 0.0 0.0082 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 RKO95781.1 - 0.029 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 RKO95781.1 - 0.085 12.6 0.0 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.12 RKO95781.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_15 PF09445.10 RKO95781.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase CbiA PF01656.23 RKO95781.1 - 0.22 11.6 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain BPL_C PF02237.17 RKO95782.1 - 3.5e-08 33.2 0.1 6.9e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain BPL_LplA_LipB PF03099.19 RKO95782.1 - 5e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family EFG_C PF00679.24 RKO95783.1 - 1.5e-16 60.2 0.0 2.2e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus Ribosomal_S19 PF00203.21 RKO95784.1 - 3.2e-34 116.7 1.0 4.5e-34 116.2 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 UMPH-1 PF05822.12 RKO95788.1 - 4.3e-40 137.8 0.0 5.7e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 RKO95788.1 - 6.1e-07 30.0 0.3 1.2e-06 29.1 0.3 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CBS PF00571.28 RKO95789.1 - 4.1e-28 97.6 3.7 6.7e-08 32.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain CH PF00307.31 RKO95791.1 - 4.3e-30 104.1 0.4 2.1e-17 63.3 0.2 2.0 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 RKO95791.1 - 5.7e-05 22.9 0.0 0.011 15.5 0.0 2.6 2 1 0 2 2 2 2 CAMSAP CH domain Casc1_N PF15927.5 RKO95792.1 - 4.4e-14 52.6 13.4 7.8e-14 51.8 13.4 1.4 1 1 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus DUF2982 PF11201.8 RKO95792.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) zf-C2H2 PF00096.26 RKO95793.1 - 1e-06 28.8 7.7 0.00038 20.7 1.3 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKO95793.1 - 3.2e-06 27.3 0.5 3.2e-06 27.3 0.5 2.1 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKO95793.1 - 4e-05 24.1 7.8 0.002 18.8 1.3 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKO95793.1 - 0.0022 18.2 0.2 0.022 15.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_9 PF14369.6 RKO95793.1 - 0.014 15.6 0.6 0.03 14.6 0.6 1.6 1 1 0 1 1 1 0 zinc-ribbon zf-C2H2_11 PF16622.5 RKO95793.1 - 0.022 14.5 1.9 0.022 14.5 1.9 2.6 2 1 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RKO95793.1 - 0.075 12.8 0.9 0.075 12.8 0.9 2.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-LYAR PF08790.11 RKO95793.1 - 0.15 12.0 1.3 0.36 10.8 0.1 2.0 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 RKO95793.1 - 0.46 10.6 7.6 1.9 8.6 7.4 2.0 1 1 1 2 2 2 0 BED zinc finger CH PF00307.31 RKO95794.1 - 4.9e-06 26.7 0.0 5.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4389 PF14333.6 RKO95795.1 - 0.076 12.9 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Glyco_hydro_9 PF00759.19 RKO95795.1 - 0.86 9.0 8.4 1.4 8.3 8.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Vps26 PF03643.15 RKO95796.1 - 1.8e-54 184.6 0.2 2e-54 184.4 0.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 gp32 PF08804.10 RKO95796.1 - 0.1 12.6 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 gp32 DNA binding protein like Zw10 PF06248.13 RKO95797.1 - 0.11 11.0 0.0 0.13 10.8 0.0 1.0 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 cNMP_binding PF00027.29 RKO95798.1 - 6.9e-18 64.5 0.0 9.7e-18 64.0 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pilosulin PF17499.2 RKO95799.1 - 0.0098 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 1 Ant venom peptides Response_reg PF00072.24 RKO95802.1 - 4.4e-23 81.6 0.1 8.9e-23 80.6 0.1 1.5 1 1 0 1 1 1 1 Response regulator receiver domain LRR_4 PF12799.7 RKO95803.1 - 5.1e-05 23.6 5.4 14 6.3 0.0 5.9 4 2 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 RKO95803.1 - 0.00036 20.3 12.5 0.1 12.7 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich repeat SAM_Ste50p PF09235.10 RKO95803.1 - 0.0025 18.0 0.2 1.9 8.8 0.0 3.2 3 0 0 3 3 3 1 Ste50p, sterile alpha motif LRR_2 PF07723.13 RKO95803.1 - 0.032 14.9 0.1 0.87 10.4 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_1 PF00560.33 RKO95803.1 - 0.74 10.6 5.9 69 4.6 0.0 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat ATG22 PF11700.8 RKO95804.1 - 4.7e-78 262.9 11.2 5.3e-78 262.8 11.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like DUF4184 PF13803.6 RKO95804.1 - 0.18 11.5 9.5 0.77 9.4 4.3 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4184) DUF5337 PF17272.2 RKO95804.1 - 0.39 10.6 5.6 1.5 8.7 2.0 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5337) Epimerase PF01370.21 RKO95805.1 - 8.6e-18 64.7 0.1 1.3e-17 64.0 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 RKO95805.1 - 4.1e-13 49.1 0.1 5.7e-13 48.6 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 RKO95805.1 - 3.8e-10 39.2 0.1 1.3e-09 37.5 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 RKO95805.1 - 2.7e-08 33.9 0.0 6.7e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 RKO95805.1 - 6.6e-08 32.3 0.0 1.1e-07 31.5 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 RKO95805.1 - 5.9e-06 25.6 1.5 0.00089 18.5 1.5 2.9 1 1 0 1 1 1 1 Male sterility protein Sacchrp_dh_NADP PF03435.18 RKO95805.1 - 0.0055 17.0 0.0 0.025 14.8 0.0 2.0 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DUF4394 PF14339.6 RKO95805.1 - 0.034 13.5 0.0 0.087 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) Rrp44_S1 PF17215.3 RKO95805.1 - 0.16 11.9 0.2 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 S1 domain NDK PF00334.19 RKO95808.1 - 1e-52 177.7 0.0 1.2e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Retrotrans_gag PF03732.17 RKO95809.1 - 0.00013 22.2 0.4 0.00024 21.3 0.2 1.6 2 0 0 2 2 2 1 Retrotransposon gag protein TPR_12 PF13424.6 RKO95810.1 - 0.00088 19.5 1.0 6.7 7.1 0.0 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKO95810.1 - 0.0049 16.9 0.9 0.59 10.4 0.0 3.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKO95810.1 - 0.0055 16.7 1.0 0.65 10.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF1266 PF06889.11 RKO95810.1 - 0.0063 16.6 0.6 0.012 15.6 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1266) TPR_1 PF00515.28 RKO95810.1 - 0.014 15.2 2.2 5.7 6.9 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 RKO95810.1 - 0.021 15.0 2.4 1.3 9.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF5457 PF17540.2 RKO95810.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5457) TPR_14 PF13428.6 RKO95810.1 - 0.34 11.8 4.1 0.93 10.5 0.0 3.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 RKO95810.1 - 0.35 11.4 4.6 0.77 10.3 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_8 PF12780.7 RKO95811.1 - 5.1e-35 121.1 0.0 8.8e-35 120.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.7 RKO95811.1 - 5.8e-35 120.9 8.3 8e-35 120.5 8.3 1.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor ATG16 PF08614.11 RKO95811.1 - 0.48 10.6 12.5 2.7 8.2 5.3 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 RKO95811.1 - 1.2 8.0 14.9 1.3 7.8 0.4 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 RKO95811.1 - 2 7.9 8.0 2.6 7.5 4.9 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit hNIFK_binding PF12196.8 RKO95812.1 - 0.025 14.1 1.0 1.8 8.2 0.7 2.4 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK CarS-like PF01864.17 RKO95812.1 - 0.079 12.9 1.0 0.15 12.0 0.1 1.8 2 0 0 2 2 2 0 CDP-archaeol synthase Far-17a_AIG1 PF04750.14 RKO95812.1 - 0.14 11.4 3.4 0.12 11.7 0.6 2.0 1 1 1 2 2 2 0 FAR-17a/AIG1-like protein Epimerase PF01370.21 RKO95813.1 - 9.3e-47 159.5 0.0 1e-46 159.3 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RKO95813.1 - 2e-44 152.4 0.0 2.3e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 RKO95813.1 - 3.1e-17 62.6 0.0 2.9e-16 59.5 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RKO95813.1 - 2.1e-14 53.2 0.0 2.5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RKO95813.1 - 3.9e-14 52.4 0.0 5e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 RKO95813.1 - 3.2e-08 33.1 0.0 2.5e-05 23.6 0.0 2.4 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 RKO95813.1 - 1.6e-07 31.4 0.0 1.9e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RKO95813.1 - 5.6e-06 26.4 0.2 2.9e-05 24.1 0.2 2.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 RKO95813.1 - 3.4e-05 23.5 0.1 4.6e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 RKO95813.1 - 0.0061 16.8 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.20 RKO95813.1 - 0.0082 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 RKO95813.1 - 0.011 16.0 0.1 0.016 15.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Methyltransf_17 PF12692.7 RKO95813.1 - 0.14 12.2 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase DUF3819 PF12842.7 RKO95814.1 - 8.1e-46 155.6 1.0 9.5e-46 155.4 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) DUF2992 PF11208.8 RKO95815.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DBINO PF13892.6 RKO95816.1 - 1.4e-43 148.4 15.0 1.4e-43 148.4 15.0 1.6 2 0 0 2 2 2 1 DNA-binding domain TAF4 PF05236.14 RKO95816.1 - 0.87 9.3 11.1 0.044 13.5 5.7 1.6 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family GTP_EFTU PF00009.27 RKO95817.1 - 0.00015 21.4 1.8 0.00073 19.1 1.7 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain YdjO PF14169.6 RKO95817.1 - 0.036 13.8 2.0 5.4 6.8 0.3 2.2 1 1 1 2 2 2 0 Cold-inducible protein YdjO Dynamin_N PF00350.23 RKO95817.1 - 0.04 14.0 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Dynamin family DUF1936 PF09151.10 RKO95817.1 - 0.082 12.8 3.5 3.6 7.6 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) MMR_HSR1 PF01926.23 RKO95817.1 - 0.13 12.4 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase Med22 PF06179.12 RKO95820.1 - 2e-11 44.1 0.0 2.7e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex VIT1 PF01988.19 RKO95821.1 - 1.4e-64 217.9 0.0 1.6e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 VIT family Cation_efflux PF01545.21 RKO95822.1 - 9e-42 143.1 12.3 5.7e-41 140.4 12.3 1.9 1 1 0 1 1 1 1 Cation efflux family ATP-synt_ab PF00006.25 RKO95823.1 - 1.6e-61 207.7 0.1 2e-61 207.4 0.1 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end PF05204.14 RKO95823.1 - 7.2e-40 135.6 0.2 8.2e-33 112.9 0.1 2.8 3 0 0 3 3 3 2 Homing endonuclease Hom_end_hint PF05203.16 RKO95823.1 - 7.4e-23 81.7 0.0 1.4e-22 80.8 0.0 1.5 2 0 0 2 2 2 1 Hom_end-associated Hint LAGLIDADG_3 PF14528.6 RKO95823.1 - 3.1e-06 27.4 0.0 0.17 12.2 0.0 3.0 2 1 1 3 3 3 2 LAGLIDADG-like domain Vps5 PF09325.10 RKO95824.1 - 7.5e-06 25.7 0.7 1e-05 25.3 0.7 1.1 1 0 0 1 1 1 1 Vps5 C terminal like FAM92 PF06730.11 RKO95824.1 - 0.019 14.4 1.0 0.024 14.1 1.0 1.1 1 0 0 1 1 1 0 FAM92 protein RVP_2 PF08284.11 RKO95825.1 - 0.0083 15.9 0.0 0.0085 15.9 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.6 RKO95825.1 - 0.099 13.2 0.0 0.11 13.1 0.0 1.1 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease SNARE PF05739.19 RKO95828.1 - 1.4e-16 60.2 3.8 3e-16 59.2 0.1 2.8 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.25 RKO95828.1 - 1.1e-06 28.5 0.9 2e-06 27.6 0.9 1.4 1 1 0 1 1 1 1 Syntaxin PIRT PF15099.6 RKO95828.1 - 0.00073 19.1 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family Tweety PF04906.13 RKO95828.1 - 0.00096 17.9 2.2 0.0034 16.1 1.1 2.1 2 1 1 3 3 3 1 Tweety Prominin PF05478.11 RKO95828.1 - 0.0025 15.8 0.7 0.0049 14.9 0.4 1.5 2 0 0 2 2 2 1 Prominin BLOC1_2 PF10046.9 RKO95828.1 - 0.042 14.2 1.5 7.7 6.9 0.0 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.11 RKO95828.1 - 0.045 12.6 0.8 0.058 12.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2019 PF09450.10 RKO95828.1 - 0.049 13.6 0.4 0.13 12.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) TraC PF07820.12 RKO95828.1 - 0.16 12.3 3.7 0.28 11.5 1.1 2.6 2 1 1 3 3 3 0 TraC-like protein HAUS-augmin3 PF14932.6 RKO95828.1 - 0.41 10.2 2.5 0.21 11.1 0.2 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Synaptobrevin PF00957.21 RKO95828.1 - 5.1 7.0 7.2 1.7 8.5 3.1 2.3 2 1 0 2 2 2 0 Synaptobrevin Ank_5 PF13857.6 RKO95829.1 - 1.4e-08 34.8 0.5 2.1e-08 34.2 0.4 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKO95829.1 - 2.7e-06 27.9 0.1 3.2e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKO95829.1 - 2.8e-05 24.2 0.1 0.00032 20.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 RKO95829.1 - 0.00015 22.1 0.8 0.0014 18.9 0.1 2.3 2 0 0 2 2 2 1 Ankyrin repeat ORC6 PF05460.13 RKO95830.1 - 0.085 12.1 0.7 0.11 11.7 0.7 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) hNIFK_binding PF12196.8 RKO95830.1 - 1.4 8.4 3.6 3 7.4 3.6 1.5 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK Brr6_like_C_C PF10104.9 RKO95831.1 - 8e-26 90.4 0.2 8.8e-26 90.3 0.2 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain NTP_transferase PF00483.23 RKO95832.1 - 2e-17 63.6 0.0 3e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 RKO95832.1 - 3.8e-06 26.4 5.4 1.3e-05 24.7 0.2 3.3 3 1 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 RKO95832.1 - 0.0017 18.0 0.5 0.028 14.2 0.1 2.5 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase KH_1 PF00013.29 RKO95833.1 - 1.8e-06 27.6 0.4 1.9e-06 27.6 0.4 1.1 1 0 0 1 1 1 1 KH domain KH_4 PF13083.6 RKO95833.1 - 0.00014 21.7 0.6 0.00015 21.5 0.6 1.2 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 RKO95833.1 - 0.00081 19.2 0.5 0.00088 19.1 0.5 1.2 1 0 0 1 1 1 1 KH domain TPH PF13868.6 RKO95836.1 - 3.6e-43 147.4 108.7 4.2e-43 147.2 108.7 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Hydrolase PF00702.26 RKO95836.1 - 1.1 9.5 8.6 1.9 8.7 8.2 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Metallophos PF00149.28 RKO95837.1 - 6.2e-06 26.9 0.2 8.5e-06 26.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF389 PF04087.14 RKO95837.1 - 0.028 14.5 0.8 0.04 14.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF389) SEP PF08059.13 RKO95838.1 - 7.7e-26 90.5 0.0 1.5e-25 89.5 0.0 1.5 2 0 0 2 2 2 1 SEP domain CENP-B_dimeris PF09026.10 RKO95839.1 - 0.00057 20.2 11.6 0.00093 19.5 11.6 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain NOA36 PF06524.12 RKO95839.1 - 0.49 9.7 10.1 0.75 9.1 10.1 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 RKO95839.1 - 1.1 7.3 6.1 1.3 7.0 6.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen YL1 PF05764.13 RKO95839.1 - 3.6 7.6 7.1 5 7.2 7.1 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 RKO95839.1 - 4 7.3 5.4 5.1 6.9 5.4 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DNA_pol_phi PF04931.13 RKO95839.1 - 4.7 5.2 10.7 6 4.8 10.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.25 RKO95840.1 - 9.8e-74 248.0 0.0 1.1e-73 247.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95840.1 - 1.2e-37 129.7 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO95840.1 - 0.00079 18.8 1.9 0.72 9.1 0.0 3.3 3 1 1 4 4 4 2 Kinase-like Pkinase_fungal PF17667.1 RKO95840.1 - 0.057 12.2 0.0 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase SET PF00856.28 RKO95841.1 - 1.5e-08 35.2 0.1 6.1e-08 33.2 0.2 1.5 1 1 1 2 2 2 1 SET domain DUF4483 PF14825.6 RKO95842.1 - 3.1e-09 36.8 0.1 6.8e-09 35.7 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4483) BROMI PF14961.6 RKO95842.1 - 0.21 8.9 0.0 0.57 7.5 0.1 1.5 2 0 0 2 2 2 0 Broad-minded protein Aminotran_1_2 PF00155.21 RKO95844.1 - 1.4e-79 267.9 0.0 1.9e-79 267.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RKO95844.1 - 9.4e-07 28.4 0.2 1.4e-06 27.8 0.2 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 RKO95844.1 - 8.4e-05 21.3 0.0 0.00016 20.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 RKO95844.1 - 0.0001 21.4 0.0 0.00019 20.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RKO95844.1 - 0.021 14.2 0.4 0.14 11.5 0.4 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_16 PF00722.21 RKO95845.1 - 3.3e-28 98.3 0.4 5e-28 97.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Thioredoxin PF00085.20 RKO95846.1 - 3e-20 72.1 0.1 3.2e-20 72.0 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 RKO95846.1 - 1.5e-07 31.5 0.3 2.7e-07 30.7 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.6 RKO95846.1 - 7.6e-06 26.2 0.1 0.063 13.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 RKO95846.1 - 2.5e-05 24.7 0.6 0.0003 21.2 0.6 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 RKO95846.1 - 8.1e-05 22.6 0.1 0.0001 22.3 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 RKO95846.1 - 0.031 14.2 0.1 0.74 9.7 0.0 2.0 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_9 PF14595.6 RKO95846.1 - 0.056 13.2 0.1 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin KaiB PF07689.12 RKO95846.1 - 0.062 13.0 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 KaiB domain OST3_OST6 PF04756.13 RKO95846.1 - 0.07 12.5 0.0 0.079 12.3 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family ApbA_C PF08546.11 RKO95847.1 - 7.4e-22 77.9 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 RKO95847.1 - 0.034 13.8 0.0 0.089 12.4 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Nitro_FeMo-Co PF02579.17 RKO95847.1 - 0.13 12.6 0.0 0.45 10.9 0.0 1.8 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Peptidase_M16_M PF16187.5 RKO95848.1 - 8.9e-54 182.7 0.0 1.2e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 RKO95848.1 - 2.2e-17 63.7 0.0 3.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Cys_Met_Meta_PP PF01053.20 RKO95849.1 - 8.3e-18 64.1 0.0 9e-18 63.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme TPR_1 PF00515.28 RKO95852.1 - 2.6e-38 128.3 9.7 1.6e-09 37.1 0.1 7.5 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 RKO95852.1 - 6e-37 122.8 9.2 5.5e-07 29.2 0.1 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 RKO95852.1 - 6.3e-31 106.7 15.0 1.6e-08 34.9 0.0 4.3 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.6 RKO95852.1 - 1.6e-27 95.6 11.8 2.6e-07 30.8 0.3 6.2 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 RKO95852.1 - 4.9e-27 94.3 3.9 1.8e-09 38.1 0.0 5.1 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_8 PF13181.6 RKO95852.1 - 1.5e-25 87.2 8.9 0.00017 21.5 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 RKO95852.1 - 2.2e-23 81.0 12.0 0.0035 18.0 0.0 7.2 1 1 6 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 RKO95852.1 - 2.8e-22 77.4 8.3 0.00012 22.3 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 RKO95852.1 - 9.8e-22 76.4 4.8 1.1e-05 25.0 0.1 5.3 3 2 3 6 6 6 4 TPR repeat TPR_7 PF13176.6 RKO95852.1 - 9.7e-20 69.1 6.3 0.00012 21.9 0.0 7.0 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 RKO95852.1 - 3e-14 52.6 14.4 0.032 14.9 0.1 7.0 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_10 PF13374.6 RKO95852.1 - 3.8e-14 52.0 13.1 0.00056 19.7 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO95852.1 - 1.2e-12 47.8 9.6 2.8e-05 24.2 0.8 3.7 2 2 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 RKO95852.1 - 3.9e-07 30.1 9.5 0.0019 18.3 0.2 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.9 RKO95852.1 - 2.1e-06 27.6 9.1 0.00061 19.5 1.3 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 RKO95852.1 - 3.5e-06 26.6 2.0 0.12 11.8 0.0 3.4 1 1 3 4 4 4 2 Coatomer epsilon subunit RPN7 PF10602.9 RKO95852.1 - 1.9e-05 24.5 2.0 0.0079 15.9 0.6 2.7 1 1 1 2 2 2 2 26S proteasome subunit RPN7 PPR PF01535.20 RKO95852.1 - 0.00017 21.6 0.4 9 6.8 0.0 4.8 5 0 0 5 5 5 0 PPR repeat TPR_4 PF07721.14 RKO95852.1 - 0.00027 21.3 7.7 1 10.2 0.0 6.1 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 RKO95852.1 - 0.00031 21.0 3.6 0.52 10.7 0.0 3.8 2 2 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 RKO95852.1 - 0.00055 19.2 9.1 0.91 8.7 0.0 3.8 1 1 3 4 4 4 1 Tetratricopeptide repeat NARP1 PF12569.8 RKO95852.1 - 0.0038 16.2 0.8 0.0038 16.2 0.8 2.1 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 PPR_2 PF13041.6 RKO95852.1 - 0.035 14.3 1.6 5.4 7.3 0.0 3.7 4 0 0 4 4 3 0 PPR repeat family PknG_TPR PF16918.5 RKO95852.1 - 0.035 12.8 1.1 0.3 9.8 0.0 2.0 1 1 0 2 2 2 0 Protein kinase G tetratricopeptide repeat MIT PF04212.18 RKO95852.1 - 0.036 14.1 5.6 7 6.8 0.0 4.9 4 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 RKO95852.1 - 0.04 13.9 0.2 0.04 13.9 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RKO95852.1 - 0.3 11.5 2.9 5.7 7.4 0.0 2.6 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation SHNi-TPR PF10516.9 RKO95852.1 - 2.3 7.7 5.4 6.6 6.3 0.1 3.4 4 0 0 4 4 3 0 SHNi-TPR Arena_RNA_pol PF06317.11 RKO95853.1 - 0.026 11.7 0.0 0.035 11.3 0.0 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase CHD5 PF04420.14 RKO95854.1 - 5.3e-21 75.1 0.0 6.2e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 CHD5-like protein MMPL PF03176.15 RKO95854.1 - 0.033 13.1 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 MMPL family Maf PF02545.14 RKO95856.1 - 2.9e-27 95.6 0.0 3.2e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein ABC_tran PF00005.27 RKO95857.1 - 0.00026 21.5 0.2 0.00041 20.9 0.2 1.3 1 0 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 RKO95857.1 - 0.0011 19.2 0.6 0.077 13.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 RKO95857.1 - 0.0019 17.9 0.1 0.0057 16.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RKO95857.1 - 0.002 18.5 1.0 0.0034 17.8 0.1 1.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 RKO95857.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 RKO95857.1 - 0.079 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 RKO95857.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 RKO95857.1 - 0.14 12.4 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 RKO95857.1 - 0.16 11.6 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RKO95857.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 RKO95857.1 - 0.26 11.2 0.0 0.37 10.7 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ras PF00071.22 RKO95857.1 - 0.28 10.8 0.0 0.43 10.2 0.0 1.2 1 0 0 1 1 1 0 Ras family AAA_23 PF13476.6 RKO95857.1 - 0.29 11.6 0.0 0.39 11.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 RKO95858.1 - 2.7e-64 217.1 0.0 3.1e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95858.1 - 2.5e-27 95.8 0.0 3.1e-27 95.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKO95858.1 - 0.00054 20.0 0.8 0.0016 18.4 0.8 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKO95858.1 - 0.0033 16.8 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKO95858.1 - 0.022 13.5 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Seadorna_VP7 PF07387.11 RKO95858.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 RKO95858.1 - 0.17 11.2 1.2 0.95 8.8 1.2 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKO95858.1 - 0.29 10.1 0.0 1.4 7.8 0.0 1.9 1 1 0 1 1 1 0 Haspin like kinase domain HlyD_D23 PF16576.5 RKO95862.1 - 0.077 12.2 6.1 0.55 9.4 0.5 2.2 2 0 0 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion EF-hand_1 PF00036.32 RKO95863.1 - 4.3e-39 129.1 11.3 4e-10 38.5 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RKO95863.1 - 7.9e-34 115.9 1.9 2.7e-16 59.8 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 RKO95863.1 - 8.9e-30 102.3 9.8 6.3e-13 48.4 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RKO95863.1 - 6.1e-28 94.3 6.9 2.1e-09 36.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RKO95863.1 - 5.4e-26 88.9 8.3 1.5e-06 27.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 RKO95863.1 - 1.1e-13 51.3 0.1 2.8e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 RKO95863.1 - 2.1e-08 34.0 0.4 0.0054 16.7 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RKO95863.1 - 2.4e-07 31.0 0.0 0.0096 16.2 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 RKO95863.1 - 6.4e-05 22.9 0.0 0.17 11.9 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 RKO95863.1 - 7.1e-05 23.6 0.0 0.0098 16.8 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 RKO95863.1 - 0.00025 21.0 0.6 0.00097 19.2 0.1 2.2 3 0 0 3 3 2 1 Ca2+ insensitive EF hand DUF3349 PF11829.8 RKO95863.1 - 0.00085 20.1 0.3 1.4 9.7 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Dockerin_1 PF00404.18 RKO95863.1 - 0.0023 18.1 6.6 0.041 14.1 0.7 3.2 1 1 2 3 3 3 1 Dockerin type I domain Caleosin PF05042.13 RKO95863.1 - 0.0032 17.4 0.5 2.5 8.0 0.0 3.1 1 1 2 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 RKO95863.1 - 0.0071 16.7 0.4 1.6 9.1 0.1 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb4 DUF1103 PF06513.11 RKO95863.1 - 0.0092 15.6 5.5 0.01 15.5 5.5 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Poly_export PF02563.16 RKO95863.1 - 0.011 16.0 0.1 0.7 10.2 0.0 2.8 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein DUF4497 PF14924.6 RKO95863.1 - 0.011 16.2 0.0 0.44 11.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) MotA_activ PF09114.10 RKO95863.1 - 0.021 14.9 0.5 0.37 11.0 0.1 2.4 1 1 0 2 2 2 0 Transcription factor MotA, activation domain EF-hand_14 PF17959.1 RKO95863.1 - 0.031 14.6 0.1 8.7 6.8 0.0 2.4 1 1 0 2 2 2 0 EF-hand domain DUF2267 PF10025.9 RKO95863.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) TerB PF05099.13 RKO95863.1 - 0.068 13.1 0.6 1.5 8.8 0.1 2.3 1 1 1 2 2 2 0 Tellurite resistance protein TerB TetR_C_7 PF14246.6 RKO95863.1 - 0.12 12.4 0.0 10 6.2 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain RuvA_C PF07499.13 RKO95863.1 - 0.13 12.8 0.1 12 6.5 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain Spore_III_AB PF09548.10 RKO95863.1 - 0.14 12.2 0.2 0.24 11.5 0.2 1.5 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PP2C PF00481.21 RKO95864.1 - 2.5e-17 63.4 0.0 4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Sec63 PF02889.16 RKO95865.1 - 9.6e-18 64.3 0.0 1.5e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain Tubulin_C PF03953.17 RKO95867.1 - 6.4e-32 110.4 0.0 7.9e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin C-terminal domain SNARE PF05739.19 RKO95868.1 - 3.6e-10 39.7 0.1 1.3e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 SNARE domain AAA_PrkA PF08298.11 RKO95868.1 - 0.0061 15.5 0.0 0.0073 15.3 0.0 1.1 1 0 0 1 1 1 1 PrkA AAA domain DUF1043 PF06295.12 RKO95868.1 - 0.031 14.3 1.1 0.031 14.3 1.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Syntaxin PF00804.25 RKO95868.1 - 0.034 13.8 1.4 0.053 13.2 1.4 1.3 1 0 0 1 1 1 0 Syntaxin DMSP_lyase PF16867.5 RKO95868.1 - 0.13 11.9 0.6 0.18 11.4 0.6 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase GTP_EFTU PF00009.27 RKO95870.1 - 6e-28 97.7 0.0 8e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 RKO95870.1 - 5.2e-10 39.6 0.5 1e-09 38.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Ras PF00071.22 RKO95870.1 - 0.034 13.8 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Ras family ATP_bind_1 PF03029.17 RKO95870.1 - 0.047 13.5 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein P16-Arc PF04699.14 RKO95871.1 - 3.5e-43 147.6 0.1 3.8e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2937 PF11157.8 RKO95871.1 - 0.0044 16.7 1.2 0.0067 16.2 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2937) Utp12 PF04003.12 RKO95871.1 - 0.023 15.0 0.0 0.049 13.9 0.0 1.5 2 0 0 2 2 2 0 Dip2/Utp12 Family DUF5595 PF18077.1 RKO95872.1 - 1.1 9.4 3.6 5.3 7.2 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Sirohm_synth_C PF14823.6 RKO95874.1 - 0.024 14.3 1.1 15 5.3 0.0 3.6 3 0 0 3 3 3 0 Sirohaem biosynthesis protein C-terminal NuiA PF07924.11 RKO95874.1 - 0.14 12.5 0.7 8.9 6.7 0.1 3.0 3 0 0 3 3 3 0 Nuclease A inhibitor-like protein DUF2115 PF09888.9 RKO95874.1 - 0.17 12.4 0.1 3.5 8.1 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) YflT PF11181.8 RKO95874.1 - 0.28 11.7 1.2 20 5.8 0.4 3.1 3 0 0 3 3 3 0 Heat induced stress protein YflT DUF2315 PF10231.9 RKO95876.1 - 0.0019 18.3 0.0 0.0084 16.2 0.0 1.8 1 1 0 1 1 1 1 Apoptogenic protein 1 DUF5450 PF17529.2 RKO95877.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5450) WD40_4 PF16300.5 RKO95879.1 - 9.8e-09 35.0 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 RKO95879.1 - 7.8e-05 23.4 1.3 0.028 15.3 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95879.1 - 0.061 13.6 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 RKO95880.1 - 1.1e-32 113.4 0.0 1.3e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cse1 PF08506.10 RKO95882.1 - 8e-104 347.4 0.0 9.5e-104 347.1 0.0 1.1 1 0 0 1 1 1 1 Cse1 Xpo1 PF08389.12 RKO95882.1 - 0.0061 16.6 0.3 0.025 14.7 0.0 2.2 3 0 0 3 3 3 1 Exportin 1-like protein PDR_CDR PF06422.12 RKO95883.1 - 7.6e-20 70.6 0.0 8.6e-20 70.4 0.0 1.0 1 0 0 1 1 1 1 CDR ABC transporter PDR_assoc PF08370.11 RKO95883.1 - 0.00036 20.2 1.2 0.0005 19.7 1.2 1.2 1 0 0 1 1 1 1 Plant PDR ABC transporter associated UPF0370 PF13980.6 RKO95883.1 - 0.044 13.8 0.8 0.059 13.4 0.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) SOXp PF12336.8 RKO95885.1 - 0.62 11.2 5.5 0.59 11.2 3.6 2.0 1 1 1 2 2 2 0 SOX transcription factor Acyl-CoA_dh_M PF02770.19 RKO95886.1 - 4.2e-17 62.1 0.1 6.8e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 RKO95886.1 - 8.7e-07 29.3 0.1 1.5e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1953 PF09196.10 RKO95886.1 - 0.15 11.9 0.1 0.51 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1953) Choline_kinase PF01633.20 RKO95888.1 - 4.7e-56 189.7 0.0 5.7e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 RKO95888.1 - 6.3e-09 36.1 2.1 1.1e-08 35.4 2.1 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 RKO95888.1 - 0.039 13.3 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase DHC_N1 PF08385.12 RKO95889.1 - 1.1e-111 374.2 7.7 1.3e-111 374.1 7.7 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF4446 PF14584.6 RKO95889.1 - 0.018 15.0 1.0 0.58 10.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) Peptidase_S64 PF08192.11 RKO95889.1 - 0.07 11.6 0.4 0.12 10.9 0.4 1.3 1 0 0 1 1 1 0 Peptidase family S64 DUF3583 PF12126.8 RKO95889.1 - 0.14 11.6 0.4 0.38 10.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3583) FliT PF05400.13 RKO95889.1 - 8.2 7.3 6.7 1.3 9.9 0.2 2.9 4 1 0 4 4 4 0 Flagellar protein FliT DUF4611 PF15387.6 RKO95890.1 - 0.0017 18.5 3.2 0.29 11.4 1.5 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4611) BSP_II PF05432.11 RKO95890.1 - 0.05 13.3 4.9 0.077 12.7 4.9 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol_phi PF04931.13 RKO95890.1 - 0.11 10.6 6.4 0.18 9.9 6.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 RKO95890.1 - 3.6 8.0 9.4 26 5.3 0.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sad1_UNC PF07738.13 RKO95891.1 - 1.4e-13 51.0 0.0 1.4e-05 25.2 0.0 2.2 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal Pkinase PF00069.25 RKO95892.1 - 7.6e-61 205.8 0.0 1.7e-60 204.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO95892.1 - 1.1e-36 126.5 0.1 4e-25 88.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RKO95892.1 - 1.1e-07 31.5 0.0 2.4e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 RKO95892.1 - 0.0023 17.9 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RKO95892.1 - 0.0032 16.9 0.0 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKO95892.1 - 0.0071 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Retrotran_gag_2 PF14223.6 RKO95893.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 RKO95893.1 - 8.7e-05 22.1 0.1 0.0022 17.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 RKO95893.1 - 0.0017 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HEAT PF02985.22 RKO95894.1 - 7.9e-09 35.0 0.3 0.0021 18.2 0.0 2.4 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 RKO95894.1 - 1e-07 32.3 0.8 0.00078 19.8 0.3 2.2 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.23 RKO95894.1 - 4.4e-05 23.4 0.1 0.0022 18.0 0.0 2.6 2 1 0 2 2 2 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 RKO95894.1 - 0.00017 22.1 0.2 0.2 12.3 0.0 2.1 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region DUF4439 PF14530.6 RKO95894.1 - 0.025 15.2 0.6 0.025 15.2 0.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4439) HEAT_EZ PF13513.6 RKO95894.1 - 0.063 13.8 0.9 0.16 12.5 0.1 2.0 3 0 0 3 3 3 0 HEAT-like repeat Ytp1 PF10355.9 RKO95895.1 - 0.0053 16.0 0.3 0.012 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF420 PF04238.12 RKO95895.1 - 0.032 14.5 0.7 0.052 13.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF420) 7tm_3 PF00003.22 RKO95895.1 - 0.041 13.6 0.4 3.5 7.3 0.1 2.0 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR SdpI PF13630.6 RKO95895.1 - 2.2 8.5 4.7 2.8 8.1 0.2 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family PRP1_N PF06424.12 RKO95896.1 - 0.14 12.5 0.1 0.2 12.0 0.1 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Mito_carr PF00153.27 RKO95897.1 - 1.2e-33 114.9 1.9 1.6e-20 72.8 0.3 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DAO_C PF16901.5 RKO95898.1 - 6.7e-41 139.1 0.1 1.2e-40 138.3 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 RKO95898.1 - 4.4e-29 102.2 0.0 5.6e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase cNMP_binding PF00027.29 RKO95899.1 - 5.2e-06 26.4 0.0 7.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4509 PF14970.6 RKO95900.1 - 0.03 14.2 0.0 0.049 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Biotin_lipoyl PF00364.22 RKO95901.1 - 2.6e-15 56.0 0.1 2.8e-15 55.9 0.1 1.0 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 RKO95901.1 - 0.011 15.6 0.0 0.15 11.9 0.0 2.0 1 1 1 2 2 2 0 Biotin-lipoyl like HlyD_3 PF13437.6 RKO95901.1 - 0.023 15.4 0.0 0.26 12.0 0.0 1.9 1 1 0 1 1 1 0 HlyD family secretion protein GCV_H PF01597.19 RKO95901.1 - 0.03 14.2 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF5089 PF17002.5 RKO95901.1 - 0.1 12.4 0.0 0.1 12.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) Mu-like_Com PF10122.9 RKO95901.1 - 0.12 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Mu-like prophage protein Com PH PF00169.29 RKO95904.1 - 0.00036 21.0 0.0 0.00072 20.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 RKO95904.1 - 0.036 14.4 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Cullin PF00888.22 RKO95905.1 - 4e-75 253.6 0.0 4.9e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Cullin family TENA_THI-4 PF03070.16 RKO95905.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.6 1 0 0 1 1 1 0 TENA/THI-4/PQQC family RNA_pol_Rpb8 PF03870.15 RKO95906.1 - 4.7e-29 101.4 0.0 5.2e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 SNAP PF14938.6 RKO95907.1 - 9.9e-21 74.4 9.1 1.3e-20 74.0 9.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP YfdX PF10938.8 RKO95907.1 - 0.025 14.5 0.2 0.025 14.5 0.2 2.1 2 0 0 2 2 2 0 YfdX protein TPR_12 PF13424.6 RKO95907.1 - 0.79 10.1 20.9 0.21 11.9 6.5 4.2 3 1 2 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 RKO95907.1 - 1.5 9.9 24.6 6.9 7.9 0.1 6.9 6 2 1 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat Arm PF00514.23 RKO95908.1 - 1e-50 168.3 10.4 5.8e-13 48.4 0.1 5.7 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat Arm_3 PF16186.5 RKO95908.1 - 2e-18 65.7 0.0 4.7e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 RKO95908.1 - 5.1e-07 30.1 1.8 0.0062 17.0 0.0 4.3 3 1 1 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 RKO95908.1 - 7.9e-07 29.4 0.1 0.012 15.9 0.0 3.7 1 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 RKO95908.1 - 3.6e-05 23.7 0.2 1.6 9.2 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat V-ATPase_H_C PF11698.8 RKO95908.1 - 0.00067 19.7 0.0 0.35 11.0 0.0 3.2 2 2 2 4 4 4 2 V-ATPase subunit H Arm_2 PF04826.13 RKO95908.1 - 0.12 11.8 0.0 12 5.3 0.0 2.7 2 1 1 3 3 3 0 Armadillo-like Adaptin_N PF01602.20 RKO95908.1 - 0.15 10.6 0.0 3 6.3 0.0 2.0 1 1 1 2 2 2 0 Adaptin N terminal region RRM_1 PF00076.22 RKO95909.1 - 1.1e-31 108.5 0.0 3.3e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-grasp_2 PF08442.10 RKO95909.1 - 2.9e-05 23.7 0.0 0.0071 15.9 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp domain RRM_occluded PF16842.5 RKO95909.1 - 0.0022 17.8 0.0 0.62 10.0 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 RKO95909.1 - 0.0086 16.1 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 RRM_5 PF13893.6 RKO95909.1 - 0.0093 15.6 0.0 0.051 13.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TetR_C_7 PF14246.6 RKO95909.1 - 0.088 12.8 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain T_cell_tran_alt PF15128.6 RKO95910.1 - 1.7 8.5 3.5 1.1 9.1 0.8 2.0 2 0 0 2 2 2 0 T-cell leukemia translocation-altered His_Phos_1 PF00300.22 RKO95912.1 - 3.5e-07 30.1 0.2 4.5e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Transketolase_C PF02780.20 RKO95913.1 - 5.9e-09 35.9 0.0 9.5e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 RKO95913.1 - 7.4e-07 29.0 0.1 7.6e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain RabGAP-TBC PF00566.18 RKO95915.1 - 1e-11 44.9 0.0 1.2e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HSP20 PF00011.21 RKO95916.1 - 2.7e-07 30.7 0.0 4.7e-05 23.5 0.0 2.2 1 1 0 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.16 RKO95916.1 - 0.018 16.1 0.0 0.021 15.8 0.0 1.5 1 1 0 1 1 1 0 CS domain DUF667 PF05018.13 RKO95917.1 - 1.6e-92 308.4 0.4 1.7e-92 308.2 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Ribosomal_L18 PF17135.4 RKO95919.1 - 2.2e-53 180.4 0.9 2.4e-53 180.3 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e TctB PF07331.11 RKO95920.1 - 0.24 11.7 5.8 1.8 8.8 1.1 2.3 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family ORC3_N PF07034.11 RKO95921.1 - 1.1e-25 90.5 0.0 1.6e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus CAF-1_p60_C PF15512.6 RKO95921.1 - 1.2 9.6 0.0 1.2 9.6 0.0 2.6 3 0 0 3 3 3 0 Chromatin assembly factor complex 1 subunit p60, C-terminal SAC3_GANP PF03399.16 RKO95922.1 - 5.5e-82 275.4 0.0 8.3e-82 274.9 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family IML1 PF12257.8 RKO95924.1 - 2.4e-55 187.7 0.0 3e-54 184.1 0.0 1.9 1 1 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 Coatomer_WDAD PF04053.14 RKO95925.1 - 5.9e-06 25.6 0.0 1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 RKO95925.1 - 0.0012 19.1 0.0 3.3 8.1 0.0 3.0 1 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain NDT80_PhoG PF05224.12 RKO95926.1 - 1.3e-14 54.9 0.0 3.8e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family HSP20 PF00011.21 RKO95928.1 - 5.3e-07 29.7 0.1 0.00037 20.6 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.16 RKO95928.1 - 0.022 15.8 0.0 0.035 15.1 0.0 1.5 1 1 0 1 1 1 0 CS domain Exo_endo_phos PF03372.23 RKO95929.1 - 2.8e-13 49.9 0.0 4.8e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family His_Phos_1 PF00300.22 RKO95930.1 - 3.5e-35 121.4 0.0 7.2e-28 97.6 0.0 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 RKO95930.1 - 1.5e-34 119.3 0.2 2e-34 118.9 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase HSP70 PF00012.20 RKO95931.1 - 9.1e-206 684.6 1.8 1e-205 684.5 1.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RKO95931.1 - 1.8e-14 53.4 0.0 2.7e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein FGGY_C PF02782.16 RKO95931.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 RKO95931.1 - 0.0078 15.5 0.1 0.021 14.1 0.1 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase StbA PF06406.11 RKO95931.1 - 0.029 13.6 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 StbA protein RNA_GG_bind PF10258.9 RKO95931.1 - 0.06 13.4 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 PHAX RNA-binding domain CDC45 PF02724.14 RKO95932.1 - 4.3e-35 121.1 0.7 4.5e-35 121.1 0.7 1.0 1 0 0 1 1 1 1 CDC45-like protein SWIB PF02201.18 RKO95934.1 - 2.1e-20 72.4 0.0 2.3e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 SWIB/MDM2 domain EFG_C PF00679.24 RKO95935.1 - 6e-22 77.5 0.0 8.3e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 RKO95935.1 - 1e-07 31.8 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor G, domain IV Ribosomal_L19 PF01245.20 RKO95936.1 - 6.8e-09 35.6 0.0 9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 EMP24_GP25L PF01105.24 RKO95937.1 - 1.4e-09 38.1 0.0 1.5e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RasGAP PF00616.19 RKO95938.1 - 1.3e-18 67.4 0.0 2.8e-18 66.4 0.0 1.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase Fe-S_biosyn PF01521.20 RKO95945.1 - 1.9e-17 63.4 0.0 6.7e-16 58.5 0.0 2.0 2 0 0 2 2 2 2 Iron-sulphur cluster biosynthesis MBOAT PF03062.19 RKO95948.1 - 1.3e-14 54.3 8.7 1.9e-14 53.8 8.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Suppressor_APC PF11414.8 RKO95949.1 - 0.11 12.6 0.3 0.2 11.7 0.3 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DRIM PF07539.12 RKO95950.1 - 5.9e-24 84.3 0.0 7.3e-24 84.0 0.0 1.0 1 0 0 1 1 1 1 Down-regulated in metastasis F5_F8_type_C PF00754.25 RKO95951.1 - 0.015 15.4 0.0 0.069 13.3 0.0 1.8 2 0 0 2 2 2 0 F5/8 type C domain ANAPC10 PF03256.16 RKO95951.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, subunit 10 (APC10) EST1_DNA_bind PF10373.9 RKO95952.1 - 4.6e-05 23.0 0.1 6.3e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain TPR_7 PF13176.6 RKO95952.1 - 0.16 12.1 0.1 9.7 6.5 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat SAM_1 PF00536.30 RKO95953.1 - 1.6e-10 41.3 0.0 2.2e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 RKO95953.1 - 4.3e-05 23.5 0.0 6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LPD26 PF18842.1 RKO95953.1 - 0.1 12.6 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Large polyvalent protein associated domain 26 Ysc84 PF04366.12 RKO95954.1 - 6.2e-33 113.3 0.1 1.8e-32 111.8 0.0 1.7 2 0 0 2 2 2 1 Las17-binding protein actin regulator Tfb2 PF03849.14 RKO95956.1 - 1.9e-109 365.9 0.4 2.2e-109 365.7 0.4 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 RKO95956.1 - 1e-20 73.9 0.6 1.9e-20 73.0 0.6 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 RKO95956.1 - 0.0047 17.1 0.0 0.0093 16.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PKcGMP_CC PF16808.5 RKO95958.1 - 0.00098 18.9 3.8 0.00098 18.9 3.8 2.5 2 1 1 3 3 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 RKO95958.1 - 0.0022 17.4 8.3 0.022 14.1 8.3 1.9 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding Fib_alpha PF08702.10 RKO95958.1 - 0.0085 16.3 0.9 0.012 15.8 0.9 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family Spc7 PF08317.11 RKO95958.1 - 0.012 14.6 6.7 0.013 14.4 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3381 PF11861.8 RKO95958.1 - 0.013 15.3 4.5 0.016 15.0 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4404 PF14357.6 RKO95958.1 - 0.017 15.7 1.4 0.017 15.7 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SlyX PF04102.12 RKO95958.1 - 0.018 15.6 3.8 0.018 15.6 3.8 2.0 1 1 1 2 2 2 0 SlyX DUF16 PF01519.16 RKO95958.1 - 0.026 15.0 1.9 0.035 14.6 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF3450 PF11932.8 RKO95958.1 - 0.033 13.5 6.4 0.04 13.2 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 RKO95958.1 - 0.05 13.7 0.7 4.1 7.4 0.0 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF641 PF04859.12 RKO95958.1 - 0.058 13.7 3.8 0.083 13.2 3.8 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) XLF PF09302.11 RKO95958.1 - 0.076 13.2 1.1 0.14 12.3 0.6 1.4 1 1 0 1 1 1 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TnpV PF14198.6 RKO95958.1 - 0.077 13.0 3.1 0.64 10.0 3.1 2.1 1 1 0 1 1 1 0 Transposon-encoded protein TnpV TMPIT PF07851.13 RKO95958.1 - 0.081 12.2 1.5 0.089 12.0 1.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Phage_GPO PF05929.11 RKO95958.1 - 0.11 12.1 2.9 0.13 11.8 2.9 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase YkyA PF10368.9 RKO95958.1 - 0.11 12.1 6.0 0.13 11.9 6.0 1.1 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein UPF0242 PF06785.11 RKO95958.1 - 0.13 12.4 4.2 0.18 11.9 4.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 RKO95958.1 - 0.13 12.3 1.3 0.17 12.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 RKO95958.1 - 0.18 10.9 5.5 0.2 10.7 5.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MerR-DNA-bind PF09278.11 RKO95958.1 - 0.18 12.3 0.8 0.18 12.3 0.8 3.8 1 1 2 4 4 4 0 MerR, DNA binding Mt_ATP-synt_D PF05873.12 RKO95958.1 - 0.19 11.6 2.4 7.8 6.3 0.3 2.0 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) ADIP PF11559.8 RKO95958.1 - 0.28 11.2 8.3 0.36 10.9 8.3 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding HAUS-augmin3 PF14932.6 RKO95958.1 - 0.44 10.1 7.3 0.52 9.9 7.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 FAM76 PF16046.5 RKO95958.1 - 0.63 9.4 4.9 1.3 8.3 4.9 1.5 1 1 0 1 1 1 0 FAM76 protein OmpH PF03938.14 RKO95958.1 - 0.8 10.0 9.9 1 9.7 9.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FlgM PF04316.13 RKO95958.1 - 1.5 9.2 5.4 3.8 7.9 3.8 2.5 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM Vir_act_alpha_C PF10400.9 RKO95958.1 - 3.1 8.6 9.2 0.2 12.3 1.6 2.2 1 1 1 2 2 2 0 Virulence activator alpha C-term Nop25 PF09805.9 RKO95958.1 - 4.2 7.8 9.2 11 6.5 9.2 1.6 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) XhlA PF10779.9 RKO95958.1 - 6.8 7.0 6.2 24 5.2 0.2 2.4 1 1 0 2 2 2 0 Haemolysin XhlA Phage_Mu_Gam PF07352.12 RKO95958.1 - 8.1 6.3 10.3 2.5 8.0 1.0 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein OB_NTP_bind PF07717.16 RKO95959.1 - 0.00027 21.2 0.0 0.001 19.4 0.0 2.0 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold TIP120 PF08623.10 RKO95960.1 - 8.4e-38 129.8 0.1 9.2e-38 129.6 0.1 1.0 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) Zw10 PF06248.13 RKO95962.1 - 2.6e-07 29.6 0.0 3e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Radical_SAM PF04055.21 RKO95963.1 - 0.025 15.0 0.0 0.048 14.0 0.0 1.5 1 0 0 1 1 1 0 Radical SAM superfamily PP2C PF00481.21 RKO95965.1 - 2.7e-74 250.0 0.0 3.1e-74 249.9 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 RKO95965.1 - 0.00096 19.1 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) LEP503 PF15221.6 RKO95967.1 - 0.49 10.8 3.5 0.83 10.0 1.0 2.1 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 PMM PF03332.13 RKO95968.1 - 3e-104 347.6 0.2 3.4e-104 347.4 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Ssl1 PF04056.14 RKO95969.1 - 2.3e-65 220.0 0.0 2.9e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 RKO95969.1 - 3.1e-12 47.1 0.0 1.3e-11 45.1 0.0 2.0 3 0 0 3 3 3 1 von Willebrand factor type A domain VWA PF00092.28 RKO95969.1 - 9.9e-05 22.7 0.0 0.00024 21.4 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain UBA PF00627.31 RKO95970.1 - 4.5e-06 26.5 0.3 9.1e-06 25.5 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain TFIIA PF03153.13 RKO95970.1 - 0.031 14.3 23.4 0.041 13.9 23.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 RKO95970.1 - 0.042 14.1 9.5 0.068 13.4 9.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Presenilin PF01080.17 RKO95970.1 - 0.39 9.4 1.3 0.36 9.6 1.3 1.1 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 RKO95970.1 - 0.57 8.4 10.9 0.75 8.0 10.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.14 RKO95970.1 - 0.81 9.6 7.8 1.3 8.9 7.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 RKO95970.1 - 1.5 8.4 24.9 2.3 7.8 24.9 1.3 1 0 0 1 1 1 0 Spt20 family Tmemb_55A PF09788.9 RKO95970.1 - 4.4 6.3 4.5 14 4.7 3.6 2.1 2 0 0 2 2 2 0 Transmembrane protein 55A DUF4834 PF16118.5 RKO95970.1 - 6.3 7.8 6.7 14 6.7 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SH3_9 PF14604.6 RKO95971.1 - 1.9e-05 24.4 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO95971.1 - 9.1e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain ABC_tran PF00005.27 RKO95974.1 - 9.2e-35 120.1 0.0 1.5e-34 119.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 RKO95974.1 - 3.9e-13 49.7 0.7 5.2e-13 49.3 0.7 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 RKO95974.1 - 2.1e-06 27.3 0.0 0.00091 18.7 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RKO95974.1 - 0.00039 20.1 0.0 0.00084 19.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 RKO95974.1 - 0.00094 18.1 0.4 0.0024 16.7 0.1 1.9 2 1 0 2 2 2 1 Predicted ATPase of the ABC class AAA_16 PF13191.6 RKO95974.1 - 0.0017 18.7 0.1 0.004 17.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 RKO95974.1 - 0.011 15.7 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 RKO95974.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 RKO95974.1 - 0.02 14.8 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF87 PF01935.17 RKO95974.1 - 0.021 14.9 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 RKO95974.1 - 0.028 14.3 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 RKO95974.1 - 0.055 13.8 0.1 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 RKO95974.1 - 0.062 13.1 0.1 1.1 9.0 0.1 2.1 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 RKO95974.1 - 0.065 12.5 0.1 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 RKO95974.1 - 0.086 12.5 0.4 0.42 10.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 RKO95974.1 - 0.097 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.6 RKO95974.1 - 0.14 11.7 0.3 0.41 10.2 0.0 1.9 2 1 1 3 3 3 0 AAA domain Flavokinase PF01687.17 RKO95976.1 - 8e-34 116.3 0.0 9.4e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase LRR_9 PF14580.6 RKO95977.1 - 3.5e-17 62.5 3.5 4.7e-17 62.0 3.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 RKO95977.1 - 7.1e-10 39.0 8.2 0.063 13.7 0.1 3.3 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO95977.1 - 1.3e-06 28.1 7.4 9.8e-05 22.0 3.7 3.5 1 1 3 4 4 4 4 Leucine rich repeat Flt3_lig PF02947.14 RKO95977.1 - 0.18 12.0 0.1 1.7 8.8 0.1 2.1 1 1 0 1 1 1 0 flt3 ligand Alpha_GJ PF03229.13 RKO95977.1 - 0.55 10.8 4.5 0.8 10.3 4.5 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J LRR_6 PF13516.6 RKO95977.1 - 0.8 9.9 3.7 44 4.5 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat UPF0182 PF03699.13 RKO95978.1 - 0.099 10.8 0.1 0.13 10.4 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) FixQ PF05545.11 RKO95978.1 - 0.11 12.4 0.2 0.71 9.9 0.1 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4381 PF14316.6 RKO95978.1 - 1.3 9.3 8.4 0.44 10.8 5.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) TraQ PF09679.10 RKO95978.1 - 1.6 8.7 4.8 0.51 10.3 0.3 2.5 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin chaperone (TraQ) THF_DHG_CYH PF00763.23 RKO95979.1 - 2.3e-19 69.7 0.0 4.8e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 RKO95979.1 - 5.3e-14 51.8 0.1 1.1e-10 41.1 0.0 3.1 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1368 PF07112.11 RKO95979.1 - 0.075 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) ALAD PF00490.21 RKO95981.1 - 8.3e-118 393.1 0.0 9.9e-118 392.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Aa_trans PF01490.18 RKO95983.1 - 8.2e-57 192.7 10.2 1.6e-56 191.8 10.2 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RKO95983.1 - 5.7e-07 28.9 15.2 2.3e-06 26.9 8.3 2.1 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family GWT1 PF06423.12 RKO95983.1 - 0.037 14.2 1.9 0.13 12.4 0.3 2.3 1 1 1 2 2 2 0 GWT1 NADHdh-2_N PF12155.8 RKO95983.1 - 5 7.6 7.1 0.91 10.0 0.6 2.7 3 0 0 3 3 3 0 NADH dehydrogenase subunit 2 N-terminal WD40 PF00400.32 RKO95985.1 - 3.5e-09 37.1 0.0 0.0013 19.5 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO95985.1 - 2.1e-08 34.4 0.0 0.002 18.4 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO95985.1 - 0.26 10.2 0.1 1.8 7.4 0.1 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Hydrophobin PF01185.18 RKO95987.1 - 0.00011 22.8 7.4 0.00021 21.9 7.3 1.5 1 1 0 1 1 1 1 Fungal hydrophobin MAS20 PF02064.15 RKO95988.1 - 1.7e-14 54.0 0.0 2e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor TPR_1 PF00515.28 RKO95988.1 - 0.0052 16.5 0.1 0.0074 16.1 0.1 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Suc_Fer-like PF06999.12 RKO95989.1 - 9.9e-21 74.5 0.1 1.1e-20 74.4 0.1 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like AAA_8 PF12780.7 RKO95991.1 - 1.6e-46 158.7 0.0 2.8e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_lid_1 PF17857.1 RKO95991.1 - 9.5e-15 54.6 0.0 2e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain PEN-2 PF10251.9 RKO95992.1 - 2.1e-23 82.6 1.7 2.3e-23 82.4 1.7 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF2569 PF10754.9 RKO95992.1 - 0.013 15.9 1.9 0.02 15.3 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Carb_kinase PF01256.17 RKO95993.1 - 3.2e-22 79.2 0.0 3.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase UPF0172 PF03665.13 RKO95994.1 - 1.6e-13 51.1 0.0 1.2e-10 41.8 0.0 2.6 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0172) ABC2_membrane PF01061.24 RKO95995.1 - 1.2e-30 106.5 20.1 1.7e-30 106.1 20.1 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 RKO95995.1 - 9.3e-07 29.4 0.0 4.6e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RKO95995.1 - 0.0062 16.4 0.1 0.011 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 RKO95995.1 - 3.9 6.5 21.9 14 4.7 22.0 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4201 PF13870.6 RKO95996.1 - 0.023 14.4 3.6 1.7 8.4 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF1664 PF07889.12 RKO95996.1 - 0.1 12.7 2.3 0.13 12.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.19 RKO95996.1 - 0.7 7.7 2.0 0.95 7.3 2.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cortex-I_coil PF09304.10 RKO95996.1 - 1.1 9.5 9.9 2.5 8.3 1.4 3.0 2 1 1 3 3 3 0 Cortexillin I, coiled coil Tropomyosin_1 PF12718.7 RKO95996.1 - 1.3 9.1 12.9 3 8.0 12.2 2.0 1 1 1 2 2 2 0 Tropomyosin like CENP-Q PF13094.6 RKO95996.1 - 1.8 8.8 21.3 1.7 8.8 10.1 2.9 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit ATG16 PF08614.11 RKO95996.1 - 3.1 8.0 23.1 90 3.2 23.4 2.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 RKO95996.1 - 6.4 6.8 7.8 73 3.4 7.8 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Cyclin_N PF00134.23 RKO95997.1 - 9.8e-49 164.3 0.0 1.9e-46 156.9 0.0 2.0 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RKO95997.1 - 1.4e-32 112.3 0.0 2.5e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain zf-C2H2_2 PF12756.7 RKO95998.1 - 1.1e-25 89.9 10.0 1.6e-23 82.9 0.7 2.9 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 RKO95998.1 - 1.4e-08 34.8 1.4 1.4e-08 34.8 1.4 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKO95998.1 - 3.1e-06 27.4 0.9 8.2e-06 26.0 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 RKO95998.1 - 0.067 14.1 4.6 0.29 12.1 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RKO95998.1 - 0.076 13.0 1.4 0.13 12.3 0.5 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3246 PF11596.8 RKO95998.1 - 0.21 11.0 1.9 0.4 10.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) NOA36 PF06524.12 RKO95998.1 - 0.43 9.9 4.0 0.99 8.7 4.0 1.6 1 0 0 1 1 1 0 NOA36 protein GPP34 PF05719.11 RKO96000.1 - 1.3e-61 208.2 1.0 1.6e-61 207.9 1.0 1.0 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Pinin_SDK_N PF04697.13 RKO96001.1 - 0.68 10.6 3.2 0.91 10.2 3.2 1.2 1 0 0 1 1 1 0 pinin/SDK conserved region Utp11 PF03998.13 RKO96002.1 - 7.2e-64 216.1 14.2 8.1e-64 215.9 14.2 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 RKO96002.1 - 0.037 13.4 0.4 0.058 12.7 0.4 1.2 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2278 PF10042.9 RKO96002.1 - 0.061 13.3 0.8 0.082 12.9 0.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) QSOX_Trx1 PF18108.1 RKO96003.1 - 0.16 12.2 0.3 0.43 10.8 0.0 1.9 2 1 0 2 2 2 0 QSOX Trx-like domain Cyclin_N PF00134.23 RKO96005.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Ran_BP1 PF00638.18 RKO96006.1 - 5.2e-08 33.2 0.0 8.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain LSM PF01423.22 RKO96007.1 - 8.7e-22 76.6 0.0 1e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKO96007.1 - 0.0013 18.8 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DNA_pol_B_exo1 PF03104.19 RKO96008.1 - 3.9e-16 59.1 0.1 5.4e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain Tub PF01167.18 RKO96009.1 - 1.2e-29 103.8 0.0 1.3e-29 103.7 0.0 1.0 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 RKO96009.1 - 0.025 14.2 0.0 0.026 14.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) DUF2533 PF10752.9 RKO96009.1 - 0.05 14.1 0.0 0.063 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) Skp1 PF01466.19 RKO96010.1 - 1.1e-27 95.8 1.0 2e-27 95.1 1.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 RKO96010.1 - 1.6e-23 82.6 0.1 4.3e-23 81.2 0.0 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.6 RKO96010.1 - 0.028 14.7 0.4 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Pyr_redox_2 PF07992.14 RKO96011.1 - 2.3e-43 148.6 0.0 2.6e-43 148.3 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO96011.1 - 1.3e-19 70.5 0.0 6.2e-16 58.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKO96011.1 - 6e-15 55.3 1.7 3.3e-14 52.8 1.7 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RKO96011.1 - 2.9e-05 23.6 0.8 4.2e-05 23.1 0.2 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 RKO96011.1 - 0.0001 21.6 0.8 0.0039 16.3 0.2 3.0 3 1 1 4 4 4 1 FAD binding domain GIDA PF01134.22 RKO96011.1 - 0.00044 19.5 1.7 0.022 13.9 1.2 2.4 1 1 1 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 RKO96011.1 - 0.001 17.9 0.0 0.015 14.1 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 RKO96011.1 - 0.0026 16.9 0.0 0.079 12.1 0.0 2.2 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 RKO96011.1 - 0.0029 17.5 2.9 0.84 9.5 0.0 3.5 2 2 2 4 4 4 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 RKO96011.1 - 0.0067 16.6 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 RKO96011.1 - 0.041 13.2 0.1 0.54 9.5 0.1 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF4150 PF13665.6 RKO96011.1 - 0.045 13.9 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) DAO PF01266.24 RKO96011.1 - 0.12 12.0 2.0 0.28 10.7 0.9 2.0 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 RKO96011.1 - 0.18 12.2 0.0 3.9 8.0 0.0 2.5 2 2 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 RKO96011.1 - 0.32 10.3 1.1 5.6 6.3 0.0 2.4 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thr_dehydrat_C PF00585.18 RKO96012.1 - 5.8e-39 131.8 0.0 2.6e-19 68.8 0.0 2.2 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase PALP PF00291.25 RKO96012.1 - 3e-26 92.5 0.6 4.6e-26 91.9 0.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CPSase_C PF18302.1 RKO96012.1 - 0.14 12.6 0.1 0.5 10.9 0.1 2.0 1 0 0 1 1 1 0 Carbamoyl phosphate synthetase C-terminal domain Glycolytic PF00274.19 RKO96013.1 - 3.8e-171 568.5 0.0 4.2e-171 568.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I UCH PF00443.29 RKO96016.1 - 3.9e-12 46.2 0.0 7.8e-12 45.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Aldedh PF00171.22 RKO96017.1 - 3.8e-108 362.0 0.0 4.1e-108 361.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M3 PF01432.20 RKO96018.1 - 0.11 11.8 1.6 1.2 8.3 0.2 2.2 1 1 1 2 2 2 0 Peptidase family M3 DAGK_cat PF00781.24 RKO96019.1 - 3.9e-25 87.9 0.0 5.9e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF1775 PF07987.11 RKO96020.1 - 0.0037 17.5 0.3 0.0063 16.8 0.3 1.3 1 0 0 1 1 1 1 Domain of unkown function (DUF1775) SHE3 PF17078.5 RKO96020.1 - 0.0089 15.8 2.4 0.015 15.1 2.4 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Golgin_A5 PF09787.9 RKO96020.1 - 0.046 13.2 5.7 0.07 12.6 5.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 RKO96020.1 - 0.067 12.5 6.9 0.12 11.7 6.9 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG5 PF10392.9 RKO96020.1 - 0.27 11.4 6.2 0.11 12.7 3.6 1.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 FUSC PF04632.12 RKO96020.1 - 0.27 9.7 3.9 0.5 8.8 3.9 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Jnk-SapK_ap_N PF09744.9 RKO96020.1 - 0.48 10.6 8.7 0.77 10.0 8.7 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 YabA PF06156.13 RKO96020.1 - 0.63 10.7 2.5 1.3 9.7 2.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA IMS PF00817.20 RKO96021.1 - 2.8e-41 141.0 0.0 4.9e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 RKO96021.1 - 9.7e-15 55.3 0.7 7.2e-14 52.5 0.2 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 RKO96021.1 - 0.00016 21.8 0.0 0.00032 20.8 0.0 1.5 1 0 0 1 1 1 1 IMS family HHH motif PT PF04886.12 RKO96022.1 - 0.015 14.8 0.7 0.015 14.8 0.7 2.0 2 0 0 2 2 2 0 PT repeat Elong-fact-P_C PF09285.11 RKO96024.1 - 6.4e-14 51.4 0.1 2.4e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Elongation factor P, C-terminal EFP_N PF08207.12 RKO96024.1 - 1.9e-09 37.4 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 RKO96024.1 - 1.9e-07 31.0 0.0 3.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain DUF2149 PF09919.9 RKO96024.1 - 0.049 13.9 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Kinesin PF00225.23 RKO96025.1 - 2.9e-73 246.7 0.0 3.2e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain WD40 PF00400.32 RKO96026.1 - 6e-15 55.4 6.8 0.0071 17.2 0.2 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.8 RKO96026.1 - 0.019 13.6 1.9 3 6.4 0.0 3.4 1 1 2 4 4 4 0 Nucleoporin Nup120/160 MoeA_N PF03453.17 RKO96026.1 - 0.13 12.1 1.2 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 MoeA N-terminal region (domain I and II) PP1_bind PF15276.6 RKO96027.1 - 1.8e-09 37.8 0.3 1.8e-09 37.8 0.3 2.7 3 0 0 3 3 3 1 Protein phosphatase 1 binding SMAP PF15477.6 RKO96027.1 - 0.0068 17.3 0.1 0.02 15.8 0.1 1.8 1 0 0 1 1 1 1 Small acidic protein family DAO PF01266.24 RKO96028.1 - 0.0063 16.1 0.0 0.0099 15.5 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase 14-3-3 PF00244.20 RKO96029.1 - 6.8e-41 140.2 3.0 7.5e-41 140.0 3.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 RKO96029.1 - 0.04 12.3 3.4 0.047 12.1 3.4 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Seryl_tRNA_N PF02403.22 RKO96029.1 - 0.071 13.3 1.9 0.15 12.3 1.9 1.6 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Hat1_N PF10394.9 RKO96030.1 - 1.4e-31 109.9 0.0 1.9e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 RKO96030.1 - 0.071 13.4 0.0 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family V_ATPase_I PF01496.19 RKO96034.1 - 8.5e-153 510.2 0.9 9.5e-153 510.0 0.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ArfGap PF01412.18 RKO96035.1 - 3.5e-43 146.4 0.7 4.3e-43 146.1 0.7 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Chitin_synth_2 PF03142.15 RKO96036.1 - 1.8e-216 719.9 4.4 2.1e-216 719.6 4.4 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 RKO96036.1 - 1e-10 41.8 3.0 2.9e-10 40.4 3.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKO96036.1 - 2.5e-09 37.4 0.0 1.4e-08 35.0 0.0 2.0 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 RKO96036.1 - 2.1e-05 24.4 0.0 0.0087 15.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 RKO96036.1 - 0.0038 16.7 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF412 PF04217.13 RKO96036.1 - 2.5 8.0 4.6 7.3 6.5 4.6 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF412 Ras PF00071.22 RKO96037.1 - 8.2e-50 168.6 0.0 1.1e-46 158.4 0.0 2.0 2 0 0 2 2 2 2 Ras family Roc PF08477.13 RKO96037.1 - 3.7e-32 111.1 0.0 5.5e-32 110.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO96037.1 - 1.7e-11 43.9 0.0 2.5e-11 43.3 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKO96037.1 - 3.8e-07 30.2 0.0 8e-07 29.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKO96037.1 - 3.9e-07 29.8 0.0 1.9e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKO96037.1 - 0.00076 19.4 0.0 0.0038 17.1 0.0 2.1 3 0 0 3 3 3 1 RsgA GTPase Gtr1_RagA PF04670.12 RKO96037.1 - 0.0011 18.3 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 RKO96037.1 - 0.0033 17.2 0.0 0.0073 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 RKO96037.1 - 0.0055 17.1 0.0 0.0078 16.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKO96037.1 - 0.01 16.1 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 RKO96037.1 - 0.033 13.5 0.1 0.061 12.6 0.0 1.4 2 0 0 2 2 2 0 Septin cobW PF02492.19 RKO96037.1 - 0.047 13.3 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.23 RKO96037.1 - 0.057 12.5 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain ABC_tran PF00005.27 RKO96037.1 - 0.057 13.9 0.0 0.12 12.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 RKO96037.1 - 0.06 13.1 0.0 0.17 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RKO96037.1 - 0.064 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 RKO96037.1 - 0.085 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region DAP3 PF10236.9 RKO96037.1 - 0.24 10.5 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Drf_GBD PF06371.13 RKO96039.1 - 0.26 10.9 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain HlyD PF00529.20 RKO96039.1 - 0.36 10.8 2.4 0.99 9.3 0.0 2.4 2 0 0 2 2 2 0 HlyD membrane-fusion protein of T1SS FA_hydroxylase PF04116.13 RKO96042.1 - 3e-26 92.3 15.3 3.9e-26 92.0 11.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily SIS PF01380.22 RKO96043.1 - 1.9e-47 160.4 0.2 5.6e-32 110.4 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 RKO96043.1 - 1e-16 61.3 0.0 2.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RKO96043.1 - 8.4e-13 48.3 0.0 2.2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RKO96043.1 - 8.8e-05 21.5 0.1 0.00015 20.8 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 RKO96043.1 - 0.051 13.6 0.0 0.3 11.1 0.0 2.2 2 1 1 3 3 3 0 SIS domain Orthopox_B11R PF07033.11 RKO96044.1 - 0.021 14.6 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus B11R protein DUF3987 PF13148.6 RKO96044.1 - 0.11 11.4 0.3 0.33 9.9 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) Filo_VP24 PF06389.11 RKO96044.1 - 0.15 11.6 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Filovirus membrane-associated protein VP24 DUF3818 PF12825.7 RKO96045.1 - 9.6e-18 64.3 0.2 5.4e-10 38.8 0.1 2.1 1 1 0 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) pPIWI_RE_REase PF18154.1 RKO96045.1 - 0.017 15.1 0.2 0.04 13.9 0.2 1.6 1 0 0 1 1 1 0 REase associating with pPIWI_RE Retinal PF15449.6 RKO96045.1 - 0.2 9.4 1.3 0.3 8.8 1.3 1.2 1 0 0 1 1 1 0 Retinal protein Stm1_N PF09598.10 RKO96045.1 - 0.26 12.2 2.2 0.54 11.1 2.2 1.5 1 0 0 1 1 1 0 Stm1 4HBT PF03061.22 RKO96046.1 - 8.4e-13 48.5 0.1 9.4e-13 48.3 0.1 1.0 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 RKO96046.1 - 6.6e-10 39.5 0.1 7.2e-10 39.4 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 RKO96046.1 - 0.00043 19.7 0.2 0.00055 19.3 0.2 1.1 1 0 0 1 1 1 1 Acyl-ACP thioesterase Pkinase PF00069.25 RKO96047.1 - 2.2e-74 250.1 0.0 2.7e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96047.1 - 1.2e-34 119.8 0.0 1.5e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RKO96047.1 - 4.7e-06 25.8 0.1 6.9e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RKO96047.1 - 0.0023 17.3 0.0 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 RKO96047.1 - 0.016 14.9 0.0 0.31 10.6 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKO96047.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.14 RKO96048.1 - 7.1e-22 77.5 0.0 7.6e-22 77.4 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein Inhibitor_I24 PF10465.9 RKO96048.1 - 0.085 12.9 0.0 0.091 12.8 0.0 1.1 1 0 0 1 1 1 0 PinA peptidase inhibitor DUF2156 PF09924.9 RKO96048.1 - 0.1 11.6 0.0 0.12 11.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) BATS PF06968.13 RKO96048.1 - 0.15 12.2 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain ABC_tran PF00005.27 RKO96051.1 - 2.1e-34 119.0 0.0 2.8e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 RKO96051.1 - 7.7e-05 22.5 0.4 0.16 11.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 RKO96051.1 - 0.0001 22.7 0.4 0.00029 21.3 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKO96051.1 - 0.00018 21.8 0.0 0.015 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 RKO96051.1 - 0.00086 18.2 0.1 0.16 10.7 0.0 2.1 2 0 0 2 2 2 2 Predicted ATPase of the ABC class SMC_N PF02463.19 RKO96051.1 - 0.0015 18.0 0.0 0.056 12.9 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RKO96051.1 - 0.0025 17.7 0.0 1.2 8.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RKO96051.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 RKO96051.1 - 0.01 15.7 0.0 0.028 14.3 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 RKO96051.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 RKO96051.1 - 0.021 14.4 0.2 2 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 RKO96051.1 - 0.093 12.7 0.0 0.64 10.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 RKO96051.1 - 0.097 12.4 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 RKO96051.1 - 0.17 12.3 0.0 21 5.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S13 PF00416.22 RKO96053.1 - 2.9e-53 179.6 3.1 3.3e-53 179.5 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 RKO96053.1 - 0.0062 15.4 0.0 0.01 14.7 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Syntaxin-6_N PF09177.11 RKO96053.1 - 0.035 14.6 0.1 0.071 13.7 0.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF1822 PF08852.11 RKO96053.1 - 0.073 12.1 0.1 0.093 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) Ferric_reduct PF01794.19 RKO96054.1 - 2.8e-21 75.9 16.3 5.1e-21 75.1 16.3 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 RKO96054.1 - 2.2e-10 40.6 0.0 4.2e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 RKO96054.1 - 6.6e-07 29.6 0.0 9.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.6 RKO96054.1 - 0.0099 16.4 16.9 0.17 12.5 1.3 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4405) DUF4131 PF13567.6 RKO96054.1 - 0.07 12.8 2.1 0.19 11.4 2.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2855 PF11017.8 RKO96057.1 - 0.038 13.7 1.7 0.055 13.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) GET2 PF08690.10 RKO96057.1 - 0.14 11.8 1.4 0.17 11.5 1.4 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIF_beta PF02270.15 RKO96058.1 - 2.7e-25 88.3 0.5 4.1e-25 87.7 0.5 1.2 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 RKO96058.1 - 1.9e-05 25.4 0.0 2.9e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Gtr1_RagA PF04670.12 RKO96059.1 - 6.6e-70 235.1 0.5 7.5e-70 234.9 0.5 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 RKO96059.1 - 6.7e-05 22.4 0.0 8.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RKO96059.1 - 0.00027 21.1 0.0 0.00046 20.4 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 RKO96059.1 - 0.0003 20.3 0.0 0.00045 19.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 RKO96059.1 - 0.0036 17.4 0.0 0.0066 16.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKO96059.1 - 0.0065 16.0 0.1 0.0086 15.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 RKO96059.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RKO96059.1 - 0.087 13.2 0.0 0.16 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Kelch_1 PF01344.25 RKO96061.1 - 2.5e-11 42.9 0.7 0.00068 19.2 1.5 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 RKO96061.1 - 7.7e-10 38.7 0.3 0.0045 17.2 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 RKO96061.1 - 1.5e-08 34.5 2.5 0.0018 18.3 0.0 4.0 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_3 PF13415.6 RKO96061.1 - 6.2e-08 32.7 7.5 0.00017 21.8 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 RKO96061.1 - 4.1e-06 26.6 2.8 0.69 10.0 0.0 4.4 4 1 0 4 4 4 2 Kelch motif Methyltransf_11 PF08241.12 RKO96062.1 - 6.7e-13 49.1 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO96062.1 - 1.3e-10 41.8 0.1 3.5e-10 40.4 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO96062.1 - 1.5e-05 25.7 0.0 4.1e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO96062.1 - 0.0082 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO96062.1 - 0.054 13.3 0.1 0.25 11.1 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain HhH-GPD PF00730.25 RKO96063.1 - 5.7e-17 62.1 0.0 1.2e-16 61.1 0.0 1.5 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RKO96063.1 - 7.4e-05 22.4 0.0 0.0002 21.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 RKO96063.1 - 1.4 9.3 8.0 0.24 11.8 3.6 2.0 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III RhoGEF PF00621.20 RKO96064.1 - 4e-43 147.8 0.0 7.4e-43 146.9 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain TYA PF01021.19 RKO96064.1 - 0.017 15.4 0.5 0.017 15.4 0.5 2.4 2 0 0 2 2 2 0 TYA transposon protein DUF1451 PF07295.11 RKO96064.1 - 0.14 12.2 0.5 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Zinc-ribbon containing domain PAP2 PF01569.21 RKO96065.1 - 1e-24 86.8 5.2 1.9e-24 85.9 5.2 1.3 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 RKO96065.1 - 2.4 7.8 9.8 15 5.2 9.8 2.0 1 1 0 1 1 1 0 PAP2 superfamily E1-E2_ATPase PF00122.20 RKO96066.1 - 8.8e-17 61.2 0.0 2.2e-16 59.9 0.0 1.6 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 RKO96066.1 - 8.1e-07 28.6 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DCAF15_WD40 PF14939.6 RKO96068.1 - 0.14 11.8 4.2 0.16 11.6 4.2 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat zf-RanBP PF00641.18 RKO96069.1 - 2 7.8 8.4 0.25 10.7 1.1 2.7 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Pkinase PF00069.25 RKO96071.1 - 5.9e-53 179.9 0.0 6.5e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96071.1 - 1.5e-31 109.6 0.0 1.7e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO96071.1 - 0.0028 17.0 0.8 0.0053 16.1 0.8 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO96071.1 - 0.0075 16.2 0.3 0.048 13.6 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 RKO96071.1 - 0.0098 14.9 0.1 0.011 14.7 0.1 1.2 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RKO96071.1 - 0.029 13.7 0.1 0.039 13.3 0.1 1.3 1 1 0 1 1 1 0 Kinase-like ABC_tran PF00005.27 RKO96072.1 - 2.9e-26 92.6 0.0 4.2e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 RKO96072.1 - 7.5e-08 32.5 0.3 0.00021 21.2 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 RKO96072.1 - 0.0024 17.8 0.0 0.0045 16.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 RKO96072.1 - 0.0033 16.9 0.3 0.041 13.3 0.3 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 RKO96072.1 - 0.0083 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase IstB_IS21 PF01695.17 RKO96072.1 - 0.02 14.7 0.1 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 RKO96072.1 - 0.041 14.3 0.2 0.1 13.0 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 RKO96072.1 - 0.077 13.4 0.5 1.5 9.3 0.5 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 RKO96072.1 - 0.15 12.3 0.4 2.7 8.3 0.4 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF724 PF05266.14 RKO96074.1 - 0.0014 18.5 2.3 0.0014 18.5 2.3 6.3 1 1 5 6 6 6 1 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.8 RKO96074.1 - 0.023 14.7 0.5 0.023 14.7 0.5 8.8 4 1 6 11 11 11 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.12 RKO96074.1 - 0.031 14.9 2.2 0.031 14.9 2.2 8.8 4 2 5 9 9 9 0 SlyX Phage_lysozyme PF00959.19 RKO96074.1 - 3.7 8.1 8.2 4.1e+02 1.5 6.5 4.1 2 1 0 2 2 2 0 Phage lysozyme RolB_RolC PF02027.17 RKO96074.1 - 8 6.1 8.4 20 4.8 1.2 2.7 1 1 1 2 2 2 0 RolB/RolC glucosidase family UDPGP PF01704.18 RKO96075.1 - 5.8e-09 35.1 0.0 6.6e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 RKO96075.1 - 0.0023 18.3 0.0 0.004 17.5 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain UAA PF08449.11 RKO96076.1 - 2e-61 207.8 3.3 2.7e-61 207.4 3.3 1.1 1 0 0 1 1 1 1 UAA transporter family Tetraspanin PF00335.20 RKO96076.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.3 2 1 0 2 2 2 0 Tetraspanin family CRT-like PF08627.10 RKO96076.1 - 0.15 11.0 4.6 0.072 12.0 0.7 1.9 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like AAA_6 PF12774.7 RKO96077.1 - 7.7e-35 120.4 0.0 4.6e-20 71.9 0.0 3.3 2 1 1 3 3 3 3 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 RKO96077.1 - 2.2e-15 56.9 0.0 4.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO96077.1 - 0.0037 17.6 1.0 0.031 14.6 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain TniB PF05621.11 RKO96077.1 - 0.22 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Pkinase PF00069.25 RKO96078.1 - 5.1e-65 219.5 0.0 9.2e-59 198.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96078.1 - 2.7e-35 121.9 0.1 5.3e-33 114.4 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RKO96078.1 - 1.2e-08 34.6 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKO96078.1 - 8.1e-05 22.1 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKO96078.1 - 0.00025 20.1 0.0 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 RKO96078.1 - 0.0028 17.6 0.0 0.005 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 RKO96078.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DMT_YdcZ PF04657.13 RKO96079.1 - 8.1e-05 22.9 1.1 0.00013 22.2 1.1 1.4 1 0 0 1 1 1 1 Putative inner membrane exporter, YdcZ RCC1 PF00415.18 RKO96080.1 - 1.6e-71 236.7 18.1 5.9e-12 46.0 0.1 7.3 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKO96080.1 - 5.7e-28 96.1 35.9 3e-07 30.0 1.8 9.0 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat Skp1_POZ PF03931.15 RKO96081.1 - 1.7e-09 37.7 0.0 2.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 RKO96081.1 - 0.0068 16.6 0.2 0.0083 16.3 0.2 1.3 1 1 0 1 1 1 1 BTB/POZ domain IFT57 PF10498.9 RKO96082.1 - 1.7e-38 132.5 0.0 1.9e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Methyltransf_15 PF09445.10 RKO96083.1 - 2.3e-28 98.9 0.0 3.4e-28 98.3 0.0 1.3 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 RKO96083.1 - 0.00032 20.5 0.0 0.00032 20.5 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 RKO96083.1 - 0.0025 17.5 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 RKO96083.1 - 0.078 13.6 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LAL_C2 PF18603.1 RKO96084.1 - 0.17 12.1 0.0 2 8.6 0.0 2.2 1 1 1 2 2 2 0 L-amino acid ligase C-terminal domain 2 ILVD_EDD PF00920.21 RKO96086.1 - 2e-41 142.2 0.0 2.2e-41 142.1 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family PMT PF02366.18 RKO96087.1 - 1.2e-78 264.1 16.4 1.5e-78 263.8 16.4 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_2 PF13231.6 RKO96087.1 - 0.0079 16.4 11.4 0.014 15.6 10.9 1.7 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF3627 PF12299.8 RKO96089.1 - 0.04 14.0 0.0 0.077 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) PK PF00224.21 RKO96090.1 - 4.3e-123 410.6 4.3 5.2e-123 410.4 4.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RKO96090.1 - 2.5e-29 101.9 0.1 6.2e-29 100.6 0.1 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 RKO96090.1 - 0.00092 18.4 0.7 0.002 17.3 0.6 1.6 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family YajC PF02699.15 RKO96090.1 - 0.012 15.5 0.3 0.16 11.9 0.1 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit Pkinase PF00069.25 RKO96091.1 - 3.3e-76 256.1 0.0 3.7e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96091.1 - 2.6e-39 135.1 0.0 2.9e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO96091.1 - 5.3e-09 35.8 0.0 8.3e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 RKO96091.1 - 8e-06 25.6 0.2 1.2e-05 25.0 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 RKO96091.1 - 0.0012 17.9 0.5 0.0016 17.5 0.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKO96091.1 - 0.011 15.1 4.1 0.083 12.2 4.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO96091.1 - 0.086 12.7 0.5 0.21 11.5 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-CCHC_4 PF14392.6 RKO96092.1 - 0.029 14.1 2.1 0.15 11.9 0.6 2.2 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.23 RKO96092.1 - 0.052 13.6 2.1 0.092 12.9 2.1 1.4 1 0 0 1 1 1 0 Zinc knuckle ABC_tran_CTD PF16326.5 RKO96095.1 - 0.4 11.0 5.8 11 6.4 0.9 2.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Palm_thioest PF02089.15 RKO96097.1 - 1.4e-07 31.7 0.0 1.4e-07 31.6 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Romo1 PF10247.9 RKO96098.1 - 0.75 10.2 6.7 0.4 11.1 3.4 2.0 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Rod_C PF10493.9 RKO96099.1 - 1e-07 30.7 0.2 1.4e-07 30.3 0.2 1.1 1 0 0 1 1 1 1 Rough deal protein C-terminal region adh_short PF00106.25 RKO96100.1 - 2.1e-07 30.6 0.2 2.9e-07 30.1 0.0 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO96100.1 - 0.0002 21.0 0.0 0.00026 20.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKO96100.1 - 0.051 13.5 0.0 0.066 13.1 0.0 1.1 1 0 0 1 1 1 0 KR domain DUF4916 PF16262.5 RKO96100.1 - 0.061 12.8 0.1 1.6 8.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4916) WGG PF10273.9 RKO96102.1 - 1.8e-08 34.9 0.1 1.8e-08 34.9 0.1 1.8 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 TFIIA PF03153.13 RKO96102.1 - 0.0024 18.0 3.0 0.0028 17.7 3.0 1.0 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FinO_N PF12602.8 RKO96102.1 - 0.11 12.8 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 Fertility inhibition protein N terminal AF-4 PF05110.13 RKO96102.1 - 0.17 10.0 0.2 0.22 9.5 0.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Cwf_Cwc_15 PF04889.12 RKO96102.1 - 0.52 10.0 4.7 0.63 9.7 4.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 RKO96103.1 - 4.3 6.6 5.9 6.3 6.0 5.9 1.1 1 0 0 1 1 1 0 NOA36 protein Methyltransf_11 PF08241.12 RKO96104.1 - 4.6e-13 49.6 0.0 1e-12 48.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO96104.1 - 2.5e-10 40.9 0.0 5.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO96104.1 - 2.9e-10 40.8 0.0 6.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO96104.1 - 1.7e-09 37.8 0.0 2.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO96104.1 - 0.00023 21.0 0.0 0.0011 18.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RKO96104.1 - 0.22 10.8 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TetR_C_11 PF16859.5 RKO96106.1 - 0.033 14.5 4.3 0.059 13.7 3.6 1.8 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4680 PF15730.5 RKO96106.1 - 0.3 11.4 6.2 0.48 10.8 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) ABC_membrane PF00664.23 RKO96107.1 - 6.1e-44 150.7 8.1 8.3e-44 150.3 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RKO96107.1 - 6.6e-33 114.1 0.0 1.1e-32 113.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 RKO96107.1 - 0.00012 21.5 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ABC_ATPase PF09818.9 RKO96107.1 - 0.00027 19.9 0.0 0.00061 18.7 0.0 1.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 RKO96107.1 - 0.00049 20.4 0.0 0.0027 18.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 RKO96107.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 RKO96107.1 - 0.013 15.9 0.1 0.033 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 RKO96107.1 - 0.055 13.3 0.0 2.6 7.8 0.0 2.3 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system HipN PF18253.1 RKO96107.1 - 0.056 13.1 0.1 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain AAA_14 PF13173.6 RKO96107.1 - 0.088 12.8 0.0 2.2 8.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 RKO96107.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit GpcrRhopsn4 PF10192.9 RKO96107.1 - 0.12 11.8 1.3 0.22 10.9 1.3 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain DUF1780 PF08682.10 RKO96109.1 - 0.16 11.6 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) Rpr2 PF04032.16 RKO96110.1 - 0.054 13.8 4.5 0.46 10.8 0.1 3.0 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain PMG PF05287.12 RKO96111.1 - 0.17 11.9 0.3 0.3 11.1 0.3 1.3 1 0 0 1 1 1 0 PMG protein Herpes_capsid PF06112.11 RKO96112.1 - 4.1 7.4 10.0 7.5 6.6 10.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SRF-TF PF00319.18 RKO96113.1 - 7.2e-20 70.2 0.0 9.6e-20 69.8 0.0 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF810 PF05664.11 RKO96114.1 - 0.0028 16.3 0.8 0.0039 15.8 0.8 1.2 1 0 0 1 1 1 1 Plant family of unknown function (DUF810) KRE1 PF17056.5 RKO96114.1 - 0.12 12.1 0.4 0.62 9.8 0.1 2.1 2 0 0 2 2 2 0 Killer toxin-resistance protein 1 SNF2_N PF00176.23 RKO96117.1 - 1.9e-54 184.7 0.0 3e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO96117.1 - 3.5e-09 37.0 0.0 4.6e-08 33.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO96117.1 - 1.4e-06 28.4 0.3 7e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HA2 PF04408.23 RKO96118.1 - 0.041 14.2 0.0 0.068 13.5 0.0 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) Prefoldin_2 PF01920.20 RKO96119.1 - 1.1e-20 73.6 0.8 1.2e-20 73.4 0.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit ASH PF15780.5 RKO96120.1 - 6.2e-05 23.1 0.1 0.00098 19.3 0.0 2.5 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Zds_C PF08632.10 RKO96121.1 - 6.4e-13 48.2 0.0 1.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term SR-25 PF10500.9 RKO96121.1 - 0.0087 15.7 46.7 0.01 15.5 11.3 2.6 3 0 0 3 3 3 2 Nuclear RNA-splicing-associated protein Macoilin PF09726.9 RKO96121.1 - 0.51 8.8 15.6 0.44 9.0 0.4 2.1 2 0 0 2 2 2 0 Macoilin family Herpes_LMP1 PF05297.11 RKO96121.1 - 1.8 7.6 5.0 3.5 6.7 5.0 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Apt1 PF10351.9 RKO96121.1 - 2.1 7.1 19.2 0.85 8.4 6.9 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain MDM1 PF15501.6 RKO96121.1 - 2.4 7.2 21.5 0.26 10.4 6.1 2.3 2 0 0 2 2 2 0 Nuclear protein MDM1 EBP50_C PF09007.11 RKO96121.1 - 3.8 8.5 23.0 6.9 7.7 11.8 2.8 2 1 0 2 2 2 0 EBP50, C-terminal EMP70 PF02990.16 RKO96122.1 - 3.5e-74 250.4 0.0 7.6e-74 249.2 0.0 1.5 1 1 0 1 1 1 1 Endomembrane protein 70 DUF3857 PF12969.7 RKO96122.1 - 0.068 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) SNF2_N PF00176.23 RKO96123.1 - 2.8e-38 131.6 1.4 3.9e-38 131.1 1.4 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO96123.1 - 3.8e-18 65.9 0.0 8.1e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 RKO96123.1 - 6.1e-06 25.6 0.1 5.9e-05 22.4 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ToxN_toxin PF13958.6 RKO96123.1 - 0.16 12.2 0.1 0.35 11.1 0.1 1.5 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system DHC_N1 PF08385.12 RKO96124.1 - 7.6e-100 335.2 2.9 1.2e-99 334.5 2.9 1.3 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 Med29 PF11568.8 RKO96124.1 - 0.024 14.8 6.1 1.4 9.2 0.0 4.0 3 1 1 4 4 4 0 Mediator complex subunit 29 DUF1664 PF07889.12 RKO96124.1 - 0.065 13.3 1.3 0.22 11.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) KNOX2 PF03791.13 RKO96124.1 - 0.49 9.9 4.0 29 4.3 0.3 3.9 4 0 0 4 4 4 0 KNOX2 domain Syntaxin_2 PF14523.6 RKO96124.1 - 0.68 10.3 6.9 29 5.1 0.7 3.9 3 1 1 4 4 4 0 Syntaxin-like protein Cpn60_TCP1 PF00118.24 RKO96125.1 - 6.2e-117 391.2 1.2 7e-117 391.0 1.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2344 PF10105.9 RKO96125.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) CSN8_PSD8_EIF3K PF10075.9 RKO96126.1 - 6.4e-15 55.4 0.1 9.3e-14 51.6 0.1 2.1 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family Pribosyltran PF00156.27 RKO96127.1 - 6.8e-07 28.9 0.9 8.9e-07 28.6 0.7 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Robl_LC7 PF03259.17 RKO96128.1 - 1e-26 92.5 0.0 1.1e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 RKO96128.1 - 0.00014 21.7 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Hydantoinase_A PF01968.18 RKO96129.1 - 1.7e-88 296.7 0.2 2.3e-88 296.2 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 RKO96129.1 - 5.3e-23 81.6 0.0 4.3e-20 72.1 0.0 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Synaptobrevin PF00957.21 RKO96131.1 - 3.4e-21 74.8 1.0 3.7e-21 74.7 1.0 1.0 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 RKO96131.1 - 0.079 12.5 0.4 0.093 12.3 0.4 1.0 1 0 0 1 1 1 0 fzo-like conserved region CelTOS PF18659.1 RKO96131.1 - 0.089 13.2 0.1 0.096 13.1 0.1 1.1 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Pil1 PF13805.6 RKO96132.1 - 1.3e-25 90.4 0.9 1.7e-25 90.0 0.9 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 CoA_transf_3 PF02515.17 RKO96132.1 - 0.006 15.7 0.1 0.0083 15.3 0.1 1.2 1 0 0 1 1 1 1 CoA-transferase family III NYD-SP28_assoc PF14775.6 RKO96132.1 - 0.035 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Sperm tail C-terminal domain UQ_con PF00179.26 RKO96138.1 - 7.1e-39 132.7 0.0 8.3e-39 132.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RKO96138.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 RKO96138.1 - 0.029 14.7 0.0 0.036 14.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain Bromodomain PF00439.25 RKO96139.1 - 6.8e-29 99.8 0.0 1.3e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Bromodomain TIMELESS PF04821.14 RKO96140.1 - 2.3e-22 79.6 0.7 2.5e-22 79.4 0.7 1.0 1 0 0 1 1 1 1 Timeless protein DRIM PF07539.12 RKO96140.1 - 0.015 13.6 0.1 0.018 13.4 0.1 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis zf-SNAP50_C PF12251.8 RKO96141.1 - 1.8e-20 73.5 1.6 2.2e-20 73.2 1.6 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal ThiJ_like PF17124.5 RKO96141.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 ThiJ/PfpI family-like CDC45 PF02724.14 RKO96142.1 - 0.9 7.7 3.0 0.94 7.7 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Sun2_CC2 PF18580.1 RKO96144.1 - 0.067 13.4 0.0 5 7.4 0.0 2.9 2 0 0 2 2 2 0 SUN2 coiled coil domain 2 DUF1216 PF06746.11 RKO96144.1 - 6.2 6.8 7.2 1 9.4 0.5 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1216) LRR_6 PF13516.6 RKO96145.1 - 1.1e-06 28.2 1.1 0.83 9.9 0.2 3.7 3 0 0 3 3 3 3 Leucine Rich repeat LRR_8 PF13855.6 RKO96145.1 - 0.0022 17.7 0.1 0.24 11.2 0.2 2.3 1 1 0 1 1 1 1 Leucine rich repeat DUF1507 PF07408.11 RKO96148.1 - 0.13 12.1 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1507) Sua5_yciO_yrdC PF01300.18 RKO96149.1 - 5.9e-55 185.5 0.0 1.7e-54 184.1 0.0 1.6 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 RKO96149.1 - 2.3e-08 34.7 0.1 3.5e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Ribosomal_L37ae PF01780.19 RKO96151.1 - 2.3e-41 139.7 12.1 2.6e-41 139.6 12.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 RKO96151.1 - 0.0018 18.2 2.2 0.0031 17.4 2.2 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 RKO96151.1 - 0.022 14.8 0.9 0.031 14.3 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Elf1 PF05129.13 RKO96151.1 - 0.031 14.3 2.5 0.048 13.7 2.5 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-RING_13 PF17977.1 RKO96151.1 - 0.036 14.2 3.1 0.054 13.6 3.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2175 PF09943.9 RKO96151.1 - 0.11 12.8 2.7 10 6.5 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) YyzF PF14116.6 RKO96151.1 - 0.15 12.1 1.6 0.36 10.9 0.3 2.0 2 0 0 2 2 2 0 YyzF-like protein VATC PF18716.1 RKO96151.1 - 0.18 11.7 3.6 9 6.2 0.1 3.0 3 0 0 3 3 3 0 Vms1-associating treble clef domain C1_2 PF03107.16 RKO96151.1 - 0.3 11.4 2.7 2 8.8 2.8 1.9 1 1 1 2 2 2 0 C1 domain zf-BED PF02892.15 RKO96151.1 - 0.53 10.3 8.7 2.6 8.1 2.5 2.4 1 1 1 2 2 2 0 BED zinc finger zf-Sec23_Sec24 PF04810.15 RKO96151.1 - 1.8 8.7 4.9 7.7 6.7 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.6 RKO96151.1 - 2.1 8.9 10.5 6 7.5 0.7 2.9 2 1 1 3 3 3 0 Zinc-finger double domain TspO_MBR PF03073.15 RKO96152.1 - 6e-36 123.5 15.6 6.7e-36 123.3 15.6 1.0 1 0 0 1 1 1 1 TspO/MBR family CcmF_C PF16327.5 RKO96152.1 - 0.086 12.1 4.9 0.1 11.9 4.9 1.2 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal Ribosomal_S14 PF00253.21 RKO96154.1 - 3.1e-14 52.5 2.2 3.4e-14 52.3 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Cyto_heme_lyase PF01265.17 RKO96155.1 - 3.8e-58 197.4 2.7 1.2e-57 195.8 2.7 1.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Noc2 PF03715.13 RKO96156.1 - 6.9e-73 245.5 0.3 1.2e-72 244.7 0.3 1.4 1 0 0 1 1 1 1 Noc2p family Nop14 PF04147.12 RKO96156.1 - 1.6e-05 23.4 0.1 1.6e-05 23.4 0.1 2.0 2 0 0 2 2 2 1 Nop14-like family Rap_GAP PF02145.15 RKO96157.1 - 2.2e-63 213.2 0.0 2.8e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP Cyclin_N PF00134.23 RKO96158.1 - 8.1e-11 41.8 0.3 1.5e-10 40.9 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 RKO96158.1 - 7.9e-10 39.1 0.3 1.1e-08 35.4 0.1 2.5 2 0 0 2 2 2 1 Cyclin C-terminal domain Vps5 PF09325.10 RKO96161.1 - 0.00013 21.6 0.4 0.00015 21.4 0.4 1.1 1 0 0 1 1 1 1 Vps5 C terminal like UPF0004 PF00919.20 RKO96161.1 - 0.025 14.6 0.3 0.086 12.9 0.0 2.1 2 1 1 3 3 3 0 Uncharacterized protein family UPF0004 p25-alpha PF05517.12 RKO96161.1 - 0.054 13.7 0.1 0.094 12.9 0.1 1.6 1 1 0 1 1 1 0 p25-alpha Ccdc124 PF06244.12 RKO96161.1 - 0.081 13.5 0.2 0.1 13.2 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 DUF4685 PF15737.5 RKO96162.1 - 0.065 13.7 2.6 0.068 13.6 0.4 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4685) TFIIA PF03153.13 RKO96162.1 - 0.14 12.1 8.5 0.17 11.8 8.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mo25 PF08569.11 RKO96164.1 - 2.5e-137 457.6 8.9 2.8e-137 457.5 8.9 1.0 1 0 0 1 1 1 1 Mo25-like DUF2749 PF10907.8 RKO96165.1 - 0.076 13.2 0.8 0.34 11.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) adh_short_C2 PF13561.6 RKO96168.1 - 1.7e-32 112.9 0.1 1.9e-32 112.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 RKO96168.1 - 3.3e-18 65.9 0.0 3.9e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase SH3_4 PF06347.13 RKO96169.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial SH3 domain PGI PF00342.19 RKO96171.1 - 6.7e-225 747.3 0.0 7.5e-225 747.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4148 PF13663.6 RKO96171.1 - 8.3e-06 25.9 0.3 2.1e-05 24.6 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4148) Glucosamine_iso PF01182.20 RKO96173.1 - 5.7e-57 193.2 0.1 6.6e-57 193.0 0.1 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF459 PF04311.13 RKO96173.1 - 0.014 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF459) Bap31_Bap29_C PF18035.1 RKO96173.1 - 0.039 13.9 0.1 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Adenylsucc_synt PF00709.21 RKO96174.1 - 3.2e-41 141.6 0.0 3.6e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase CDH-cyt PF16010.5 RKO96174.1 - 0.042 13.5 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase SPC25 PF06703.11 RKO96175.1 - 4e-22 78.7 0.1 5e-21 75.2 0.1 2.0 1 1 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Elf1 PF05129.13 RKO96176.1 - 1.8e-30 104.8 0.7 2e-30 104.7 0.7 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Vps36-NZF-N PF16988.5 RKO96176.1 - 0.00015 21.1 0.3 0.00021 20.6 0.3 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain GATA PF00320.27 RKO96176.1 - 0.013 15.1 0.2 0.023 14.3 0.2 1.4 1 0 0 1 1 1 0 GATA zinc finger DUF4432 PF14486.6 RKO96176.1 - 0.017 13.9 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) zf-Sec23_Sec24 PF04810.15 RKO96176.1 - 0.052 13.6 1.6 0.2 11.8 0.2 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-met PF12874.7 RKO96176.1 - 0.16 12.4 0.2 0.16 12.4 0.2 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PE_PPE_C PF12484.8 RKO96177.1 - 9.3 7.2 11.7 0.18 12.7 4.1 2.1 2 1 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal Peptidase_S8 PF00082.22 RKO96178.1 - 5.7e-19 68.5 0.1 7e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 Subtilase family Peptidase_S8_N PF16361.5 RKO96178.1 - 0.0053 17.2 0.0 0.009 16.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal of Subtilase family CTP_synth_N PF06418.14 RKO96180.1 - 3.8e-126 419.8 0.0 4.8e-126 419.5 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 RKO96180.1 - 6.8e-34 117.3 0.0 1.1e-33 116.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Hydantoinase_B PF02538.14 RKO96181.1 - 5.4e-138 460.6 0.3 6.2e-138 460.4 0.3 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Pyrophosphatase PF00719.19 RKO96182.1 - 2.9e-59 199.5 0.2 3.7e-59 199.1 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase DEAD PF00270.29 RKO96183.1 - 2.6e-25 89.2 0.4 3.6e-24 85.5 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 RKO96183.1 - 1.3e-15 57.8 0.0 2.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKO96183.1 - 2.8e-10 40.5 0.0 4.6e-09 36.6 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Sec63 PF02889.16 RKO96183.1 - 0.00012 21.4 1.2 0.0002 20.6 1.2 1.4 1 0 0 1 1 1 1 Sec63 Brl domain AAA_22 PF13401.6 RKO96183.1 - 0.00032 21.0 0.2 0.0011 19.3 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO96183.1 - 0.0095 15.7 0.4 0.023 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 RKO96183.1 - 0.014 15.8 0.2 0.17 12.3 0.2 2.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 RKO96183.1 - 0.032 14.0 0.2 0.096 12.5 0.0 1.7 1 1 0 2 2 2 0 AAA domain COesterase PF00135.28 RKO96186.1 - 0.012 14.5 0.1 0.017 14.0 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family Pkinase PF00069.25 RKO96187.1 - 0.0052 16.2 0.0 0.0066 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CAP_N PF01213.19 RKO96188.1 - 0.81 9.1 2.7 1.6 8.1 2.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PDZ_6 PF17820.1 RKO96189.1 - 0.02 14.7 0.2 0.045 13.6 0.2 1.6 1 0 0 1 1 1 0 PDZ domain bZIP_2 PF07716.15 RKO96192.1 - 4.4e-09 36.3 5.1 9.2e-09 35.2 5.1 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 RKO96192.1 - 3.9e-08 33.3 3.3 6.4e-08 32.6 3.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 RKO96192.1 - 0.0046 17.5 4.2 0.0077 16.7 4.2 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2064 PF09837.9 RKO96192.1 - 0.16 11.8 0.6 0.27 11.0 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2064) TPH PF13868.6 RKO96193.1 - 2e-45 154.8 99.3 2e-45 154.8 99.3 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain DUF3138 PF11336.8 RKO96193.1 - 5.9 5.4 6.9 9.7 4.7 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Pkinase PF00069.25 RKO96194.1 - 1.8e-65 220.9 0.0 2.3e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96194.1 - 1.8e-30 106.1 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 RKO96194.1 - 4.6e-07 30.1 0.0 7.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 RKO96194.1 - 8e-07 28.7 0.0 7.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKO96194.1 - 8.8e-05 21.6 0.0 0.00012 21.2 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKO96194.1 - 0.00028 20.3 0.0 0.00051 19.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 RKO96194.1 - 0.00095 18.8 0.0 0.13 11.8 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKO96194.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 RKO96194.1 - 0.08 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-RVT PF13966.6 RKO96195.1 - 0.012 16.3 0.0 0.023 15.4 0.0 1.5 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase Cation_efflux PF01545.21 RKO96196.1 - 6.2e-44 150.1 12.9 7.4e-44 149.9 12.9 1.1 1 0 0 1 1 1 1 Cation efflux family CBP_BcsR PF10945.8 RKO96196.1 - 0.1 12.1 0.6 30 4.2 0.1 3.3 3 0 0 3 3 3 0 Cellulose biosynthesis protein BcsR Y_phosphatase PF00102.27 RKO96198.1 - 5.8e-62 209.3 0.0 7e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RKO96198.1 - 0.0062 16.5 0.0 0.0093 15.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 RKO96198.1 - 0.019 14.7 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RKO96198.1 - 0.24 11.5 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate CAF1C_H4-bd PF12265.8 RKO96199.1 - 4.4e-16 58.9 0.0 1e-15 57.7 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 RKO96199.1 - 5.4e-08 33.4 3.1 1.2e-06 29.1 0.0 4.0 3 1 0 3 3 3 1 WD domain, G-beta repeat ATP_bind_1 PF03029.17 RKO96200.1 - 1.7e-81 273.5 0.1 2e-81 273.4 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 RKO96200.1 - 6e-05 22.9 0.0 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 RKO96200.1 - 7.1e-05 22.6 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 RKO96200.1 - 0.00012 21.8 0.0 0.00077 19.1 0.0 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 RKO96200.1 - 0.0023 18.1 0.0 0.0046 17.1 0.0 1.7 1 1 1 2 2 2 1 Helicase HerA, central domain NTPase_1 PF03266.15 RKO96200.1 - 0.0064 16.4 0.1 2.7 7.9 0.0 2.4 3 0 0 3 3 2 1 NTPase AAA_16 PF13191.6 RKO96200.1 - 0.0068 16.8 0.1 0.059 13.7 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 RKO96200.1 - 0.0074 16.8 0.0 0.022 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKO96200.1 - 0.0085 16.4 0.1 0.033 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 RKO96200.1 - 0.0093 16.5 0.0 0.018 15.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 RKO96200.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.5 2 0 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 RKO96200.1 - 0.014 15.4 0.3 0.81 9.6 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase AAA_14 PF13173.6 RKO96200.1 - 0.014 15.4 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 RKO96200.1 - 0.017 14.6 0.9 0.53 9.8 0.9 2.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RKO96200.1 - 0.018 14.4 0.1 0.16 11.3 0.1 2.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region T2SSE PF00437.20 RKO96200.1 - 0.02 14.0 0.0 0.047 12.7 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 RKO96200.1 - 0.035 14.2 0.0 0.086 12.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 RKO96200.1 - 0.042 14.3 0.3 0.57 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RKO96200.1 - 0.047 13.6 0.4 0.13 12.2 0.4 1.8 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 RKO96200.1 - 0.061 13.7 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 RKO96200.1 - 0.073 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 RKO96200.1 - 0.085 12.2 0.0 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.6 RKO96200.1 - 0.089 13.1 0.3 0.26 11.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 RKO96200.1 - 0.095 12.3 0.1 0.54 9.8 0.0 2.0 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 RKO96200.1 - 0.11 11.7 1.2 0.39 9.9 0.1 2.2 3 0 0 3 3 3 0 NB-ARC domain AAA_33 PF13671.6 RKO96200.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RKO96200.1 - 0.12 11.7 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 RKO96200.1 - 0.12 11.9 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ADK PF00406.22 RKO96200.1 - 0.14 12.3 0.7 5.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase DUF871 PF05913.11 RKO96200.1 - 0.16 11.1 0.3 0.22 10.7 0.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) PRE_C2HC PF07530.11 RKO96200.1 - 0.18 11.9 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Associated with zinc fingers HEAT PF02985.22 RKO96201.1 - 5.8e-10 38.6 0.3 0.15 12.4 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 RKO96201.1 - 2.2e-07 31.2 0.5 0.011 16.3 0.0 5.2 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 RKO96201.1 - 1.6e-06 28.2 0.0 1.6e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 RKO96201.1 - 6.3e-06 25.7 0.0 1.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Vac14_Fab1_bd PF12755.7 RKO96201.1 - 6.8e-05 23.4 0.0 0.21 12.2 0.0 2.9 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 RKO96201.1 - 0.00015 22.1 0.2 0.062 13.7 0.0 3.4 2 1 0 3 3 3 1 HEAT repeats CLASP_N PF12348.8 RKO96201.1 - 0.011 15.3 0.0 0.9 9.1 0.0 2.9 2 1 0 2 2 2 0 CLASP N terminal Pkinase_Tyr PF07714.17 RKO96201.1 - 0.026 13.8 0.0 0.2 10.9 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase DUF3458 PF11940.8 RKO96201.1 - 0.027 14.9 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Ig-like fold Adaptin_N PF01602.20 RKO96201.1 - 0.14 10.7 0.1 0.23 10.0 0.1 1.4 1 0 0 1 1 1 0 Adaptin N terminal region P34-Arc PF04045.14 RKO96202.1 - 2.1e-102 342.0 0.0 2.4e-102 341.7 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc NAD_binding_1 PF00175.21 RKO96203.1 - 1e-18 67.9 0.0 1.3e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RPN1_C PF18051.1 RKO96204.1 - 4.5e-32 109.8 0.0 5.3e-32 109.6 0.0 1.1 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal Brix PF04427.18 RKO96205.1 - 2.7e-25 89.6 0.7 4e-25 89.0 0.7 1.3 1 0 0 1 1 1 1 Brix domain GalKase_gal_bdg PF10509.9 RKO96206.1 - 3.4e-21 74.5 0.0 8.4e-21 73.3 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 RKO96206.1 - 1.2e-13 51.1 5.3 2e-13 50.3 5.3 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain RNase_II_C_S1 PF18614.1 RKO96206.1 - 0.028 14.4 0.2 0.072 13.0 0.2 1.6 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain zf-MYND PF01753.18 RKO96210.1 - 0.001 19.1 6.4 0.0019 18.3 6.4 1.5 1 0 0 1 1 1 1 MYND finger YpzG PF14139.6 RKO96210.1 - 0.065 13.4 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 YpzG-like protein Glyco_hydro_4C PF11975.8 RKO96210.1 - 0.26 11.3 0.5 0.48 10.5 0.5 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Chitin_synth_1 PF01644.17 RKO96211.1 - 9.2e-76 253.3 0.0 1.1e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 RKO96211.1 - 2.2e-17 62.8 0.2 3.7e-17 62.0 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal HrpB1_HrpK PF09613.10 RKO96212.1 - 0.11 12.1 0.0 19 4.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_1 PF00515.28 RKO96214.1 - 0.024 14.4 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKO96214.1 - 0.027 14.6 0.1 0.23 11.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKO96214.1 - 0.074 13.4 0.3 0.26 11.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKO96214.1 - 0.2 11.6 2.5 0.54 10.2 0.3 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex16 PF08610.10 RKO96215.1 - 3.5e-24 85.6 0.0 4.4e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Microtub_bd PF16796.5 RKO96215.1 - 4.3e-09 36.5 0.1 5.8e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Microtubule binding Kinesin PF00225.23 RKO96215.1 - 5.2e-05 22.3 0.0 6.1e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain CPP1-like PF11833.8 RKO96215.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like LSM PF01423.22 RKO96216.1 - 4.7e-14 51.8 0.1 6e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKO96216.1 - 0.026 14.7 0.0 0.037 14.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain P2_N PF18628.1 RKO96216.1 - 0.17 11.6 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Viral coat protein P2 N-terminal domain zf-NPL4 PF05020.15 RKO96220.1 - 2.6e-58 196.3 0.0 3.4e-58 195.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region NPL4 PF05021.15 RKO96220.1 - 9.3e-15 54.8 0.0 1.2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 NPL4 family UN_NPL4 PF11543.8 RKO96220.1 - 0.00054 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 VPS9 PF02204.18 RKO96221.1 - 9.8e-19 67.5 0.0 7.2e-18 64.7 0.0 2.1 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Clathrin PF00637.20 RKO96222.1 - 5e-13 49.2 0.1 1.6e-11 44.2 0.2 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_11 PF13414.6 RKO96222.1 - 0.034 13.8 0.6 0.95 9.2 0.1 2.6 2 0 0 2 2 2 0 TPR repeat Vps8 PF12816.7 RKO96222.1 - 0.11 12.0 0.2 0.28 10.7 0.2 1.7 1 1 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 GHMP_kinases_N PF00288.26 RKO96223.1 - 2.4e-15 56.5 3.3 9.5e-15 54.6 3.3 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 RKO96223.1 - 1.6e-06 28.4 0.2 5.2e-06 26.7 0.2 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal NYN PF01936.18 RKO96225.1 - 1.8e-10 41.5 0.0 2.5e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 NYN domain Sec1 PF00995.23 RKO96226.1 - 3.3e-104 350.2 0.1 3.9e-104 350.0 0.1 1.0 1 0 0 1 1 1 1 Sec1 family Peptidase_S49 PF01343.18 RKO96227.1 - 1.2e-08 35.1 0.0 1.7e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S49 DUF1644 PF07800.12 RKO96228.1 - 0.16 12.0 0.6 0.33 11.0 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) EMP70 PF02990.16 RKO96230.1 - 1.8e-60 205.1 15.3 2.3e-60 204.8 15.3 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 4HBT PF03061.22 RKO96231.1 - 8e-07 29.3 0.0 0.02 15.3 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Aida_N PF08910.10 RKO96231.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Aida N-terminus Phage_holin_3_6 PF07332.11 RKO96235.1 - 0.0053 16.8 0.2 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Putative Actinobacterial Holin-X, holin superfamily III DUF2157 PF09925.9 RKO96235.1 - 0.056 13.2 0.1 0.079 12.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) LysE PF01810.18 RKO96235.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 LysE type translocator Ribosomal_L30 PF00327.20 RKO96237.1 - 2.2e-12 46.6 0.1 2.4e-12 46.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e WD40 PF00400.32 RKO96238.1 - 2.7e-07 31.1 2.9 0.084 13.8 0.1 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat Dynein_IC2 PF11540.8 RKO96238.1 - 0.00058 19.8 0.1 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 PF12894.7 RKO96238.1 - 0.029 14.6 0.0 0.28 11.5 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain NDK PF00334.19 RKO96241.1 - 9.5e-22 77.5 0.0 1.1e-21 77.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF615 PF04751.14 RKO96241.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF615) MBF1 PF08523.10 RKO96244.1 - 6.2e-16 58.6 7.1 1.5e-15 57.4 7.1 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 RKO96244.1 - 5.3e-09 36.0 0.4 5.3e-09 36.0 0.4 1.5 2 0 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 RKO96244.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 RKO96244.1 - 0.032 14.3 0.2 0.051 13.6 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain MerR-DNA-bind PF09278.11 RKO96245.1 - 0.007 16.9 0.3 0.013 16.0 0.3 1.4 1 0 0 1 1 1 1 MerR, DNA binding DUF3784 PF12650.7 RKO96246.1 - 0.1 12.8 1.0 0.15 12.3 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) HD_3 PF13023.6 RKO96250.1 - 2.2e-38 131.8 0.1 2.6e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 RKO96250.1 - 4.1e-10 39.7 0.0 5.3e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 RKO96250.1 - 0.00023 21.4 0.1 0.00037 20.7 0.1 1.3 1 0 0 1 1 1 1 HD domain DUF3523 PF12037.8 RKO96250.1 - 0.0029 17.0 0.4 0.0039 16.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3523) DUF3896 PF13035.6 RKO96250.1 - 0.11 12.7 0.4 0.18 12.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Robl_LC7 PF03259.17 RKO96254.1 - 3.8e-15 55.4 0.1 5e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LSM PF01423.22 RKO96255.1 - 1.9e-10 40.3 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain TLD PF07534.16 RKO96256.1 - 5.3e-23 81.8 0.0 5.9e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 TLD CLTH PF10607.9 RKO96258.1 - 1.8e-35 122.0 0.0 2.3e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 RKO96258.1 - 3.8e-09 36.2 0.3 1e-08 34.8 0.1 1.9 2 0 0 2 2 2 1 LisH TPR_14 PF13428.6 RKO96258.1 - 0.1 13.4 1.4 3.8 8.6 0.1 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 RKO96259.1 - 6.5e-15 55.0 0.0 1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 RKO96259.1 - 0.0025 17.6 0.1 0.26 11.3 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 RKO96259.1 - 0.025 15.0 0.0 0.12 12.9 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain pair SlyX PF04102.12 RKO96259.1 - 0.15 12.7 0.7 9.4 6.9 0.5 2.9 2 0 0 2 2 2 0 SlyX TEX13 PF15186.6 RKO96259.1 - 0.85 9.3 4.1 1.9 8.1 4.1 1.5 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DASH_Dad2 PF08654.10 RKO96260.1 - 0.16 12.4 3.9 28 5.2 0.2 3.9 2 1 2 4 4 4 0 DASH complex subunit Dad2 Mitofilin PF09731.9 RKO96261.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pkinase PF00069.25 RKO96262.1 - 3.9e-65 219.8 0.0 4.4e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96262.1 - 1.2e-45 155.8 0.0 1.5e-45 155.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO96262.1 - 1.4e-08 33.9 0.0 1.9e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 RKO96262.1 - 2.6e-08 33.5 0.0 8.4e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKO96262.1 - 2.6e-05 23.4 0.0 3.1e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 RKO96262.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 RKO96262.1 - 0.054 13.4 0.0 0.2 11.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family MAT1 PF06391.13 RKO96263.1 - 4.2e-20 72.5 0.6 4.8e-20 72.3 0.6 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 RKO96263.1 - 5.7e-20 70.9 6.9 8e-20 70.5 6.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 RKO96263.1 - 6.8e-06 25.8 8.7 1.4e-05 24.8 8.8 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKO96263.1 - 6.8e-06 25.8 9.3 0.00014 21.6 10.7 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKO96263.1 - 9.1e-06 25.4 7.3 1.8e-05 24.5 7.3 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO96263.1 - 1.2e-05 25.5 7.6 1.9e-05 24.9 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 RKO96263.1 - 1.4e-05 24.9 8.3 0.00023 21.1 9.5 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.6 RKO96263.1 - 4.3e-05 23.2 5.3 0.00051 19.8 2.5 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 RKO96263.1 - 0.00065 19.7 9.5 0.0011 18.9 9.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 RKO96263.1 - 0.0019 18.0 10.7 0.14 12.1 11.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DUF3797 PF12677.7 RKO96263.1 - 0.0081 16.0 0.8 0.0081 16.0 0.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3797) Zn_Tnp_IS1 PF03811.13 RKO96263.1 - 0.028 14.1 2.4 4.5 7.1 0.1 2.4 2 0 0 2 2 2 0 InsA N-terminal domain zf-RING_6 PF14835.6 RKO96263.1 - 0.58 10.1 4.4 5.3 7.0 1.5 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein HypA PF01155.19 RKO96263.1 - 1 9.4 4.4 9.2 6.3 4.8 2.0 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Opy2 PF09463.10 RKO96263.1 - 1.6 9.1 9.7 3.8 7.9 0.6 2.8 3 0 0 3 3 3 0 Opy2 protein GAGA PF09237.11 RKO96263.1 - 2.5 8.0 6.2 12 5.8 1.3 3.0 3 0 0 3 3 3 0 GAGA factor zf-C3HC4_4 PF15227.6 RKO96263.1 - 3.2 8.0 10.5 29 4.9 10.9 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RRN7 PF11781.8 RKO96263.1 - 3.3 7.5 6.6 18 5.1 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Ribosomal_L22 PF00237.19 RKO96264.1 - 1.7e-14 53.9 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PABP PF00658.18 RKO96265.1 - 1.2e-13 51.0 0.7 3.1e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Spt20 PF12090.8 RKO96265.1 - 6 6.4 22.3 12 5.4 22.3 1.6 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 RKO96265.1 - 6.1 7.5 17.0 0.87 10.2 13.2 1.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rer1 PF03248.13 RKO96266.1 - 1.3e-74 249.7 3.7 1.4e-74 249.5 3.7 1.0 1 0 0 1 1 1 1 Rer1 family DUF4131 PF13567.6 RKO96266.1 - 0.027 14.1 6.4 1.3 8.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2208 PF09973.9 RKO96266.1 - 0.028 14.1 0.5 0.028 14.1 0.5 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Peptidase_A21 PF03566.13 RKO96267.1 - 5.2 5.2 9.7 5.6 5.1 9.7 1.0 1 0 0 1 1 1 0 Peptidase family A21 PLDc_2 PF13091.6 RKO96268.1 - 4e-06 26.8 0.0 6.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 RKO96268.1 - 0.00016 21.7 0.1 0.00031 20.8 0.1 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif SH3_9 PF14604.6 RKO96270.1 - 2e-09 37.2 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO96270.1 - 5.1e-07 29.2 0.0 1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Phage_holin_2_4 PF16082.5 RKO96270.1 - 0.028 14.1 0.7 0.072 12.8 0.7 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like YiaAB PF05360.14 RKO96270.1 - 1.6 9.0 4.0 0.46 10.7 0.3 2.0 2 0 0 2 2 2 0 yiaA/B two helix domain MBOAT PF03062.19 RKO96272.1 - 3.1e-05 23.5 1.6 3.1e-05 23.5 1.6 2.0 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family CK_II_beta PF01214.18 RKO96275.1 - 2.4e-63 213.3 0.0 2.7e-63 213.1 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit E1-E2_ATPase PF00122.20 RKO96276.1 - 0.0027 17.3 0.2 0.0034 16.9 0.2 1.1 1 0 0 1 1 1 1 E1-E2 ATPase E1-E2_ATPase PF00122.20 RKO96277.1 - 1.6e-35 122.2 2.1 1.6e-35 122.2 2.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 RKO96277.1 - 2.8e-14 52.6 0.1 9.5e-14 50.8 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF2207 PF09972.9 RKO96277.1 - 0.81 8.4 5.9 1.7 7.3 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Vps26 PF03643.15 RKO96278.1 - 1.3e-18 67.0 0.1 1.5e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 RKO96278.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DnaJ PF00226.31 RKO96280.1 - 1.4e-25 89.1 4.0 1.6e-25 89.0 4.0 1.0 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 RKO96280.1 - 0.078 12.9 0.1 0.22 11.5 0.0 1.7 1 1 1 2 2 2 0 A repeated domain in UCH-protein DUF4201 PF13870.6 RKO96281.1 - 3.5e-30 105.1 19.6 3.5e-30 105.1 19.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) Enkurin PF13864.6 RKO96281.1 - 0.021 15.2 23.0 0.9 10.0 5.7 3.1 1 1 1 2 2 2 0 Calmodulin-binding FAM76 PF16046.5 RKO96281.1 - 1.4 8.2 18.2 1.9 7.7 18.2 1.2 1 0 0 1 1 1 0 FAM76 protein Helicase_C PF00271.31 RKO96282.1 - 1.8e-13 50.8 0.0 5e-13 49.4 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 RKO96282.1 - 1.6e-05 25.1 0.1 3.2e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) ResIII PF04851.15 RKO96282.1 - 0.026 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DEAD PF00270.29 RKO96283.1 - 5.7e-34 117.4 0.0 3.5e-33 114.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO96283.1 - 3.2e-28 98.3 0.0 1.3e-26 93.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO96283.1 - 0.015 15.3 0.0 0.16 12.0 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit CMS1 PF14617.6 RKO96283.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_L26 PF16906.5 RKO96283.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.4 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Tap-RNA_bind PF09162.10 RKO96283.1 - 0.21 11.4 0.3 19 5.2 0.1 3.0 2 1 1 3 3 3 0 Tap, RNA-binding Pkinase PF00069.25 RKO96285.1 - 7.4e-69 232.0 0.0 8.4e-69 231.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96285.1 - 7.8e-35 120.4 0.0 9.8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO96285.1 - 1.3e-06 27.9 0.0 3.3e-06 26.6 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Atx10homo_assoc PF09759.9 RKO96288.1 - 0.015 15.3 0.0 0.13 12.3 0.0 2.4 1 1 1 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 RKO96288.1 - 0.17 11.3 0.0 0.63 9.4 0.0 2.0 3 0 0 3 3 3 0 Armadillo-like MLVIN_C PF18697.1 RKO96290.1 - 0.0011 19.0 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain Pkinase PF00069.25 RKO96291.1 - 2.7e-39 135.1 0.1 3.1e-39 135.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96291.1 - 1.2e-28 100.2 0.0 1.3e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO96291.1 - 0.00012 21.0 0.2 0.00018 20.4 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKO96291.1 - 0.0032 17.4 0.1 0.014 15.3 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 RKO96291.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 RKO96291.1 - 0.029 13.3 0.1 0.48 9.3 0.1 2.0 1 1 0 1 1 1 0 Haspin like kinase domain ABC1 PF03109.16 RKO96291.1 - 0.046 13.9 0.0 0.073 13.2 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Kdo PF06293.14 RKO96291.1 - 0.23 10.8 0.8 0.43 9.9 0.7 1.2 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2012 PF09430.10 RKO96292.1 - 5.2e-29 100.9 0.0 6.6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 RKO96292.1 - 0.00033 20.6 0.0 0.00055 19.9 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain CarboxypepD_reg PF13620.6 RKO96292.1 - 0.00037 20.7 0.1 0.00058 20.1 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 RKO96292.1 - 0.073 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II TMF_TATA_bd PF12325.8 RKO96293.1 - 0.016 15.4 2.8 0.016 15.4 2.8 7.1 3 1 4 7 7 7 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 RKO96293.1 - 0.041 14.4 75.5 0.1 13.1 19.2 6.3 3 1 3 6 6 6 0 Apg6 coiled-coil region OmpH PF03938.14 RKO96293.1 - 0.15 12.4 71.8 3.6 7.9 0.0 6.5 3 1 2 5 5 5 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.11 RKO96293.1 - 0.92 9.9 6.8 40 4.7 0.0 4.9 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) HSP90 PF00183.18 RKO96294.1 - 2.2e-233 775.9 23.2 2.6e-233 775.6 23.2 1.0 1 0 0 1 1 1 1 Hsp90 protein Cofac_haem_bdg PF04187.13 RKO96294.1 - 0.0016 18.5 0.4 0.0057 16.7 0.0 2.1 2 0 0 2 2 2 1 Haem-binding uptake, Tiki superfamily, ChaN SAM_3 PF18016.1 RKO96294.1 - 0.037 13.8 0.2 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Peptidase_M1 PF01433.20 RKO96295.1 - 4.6e-32 111.4 0.0 6.1e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 RKO96295.1 - 4.7e-26 91.1 0.0 8.9e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 RKO96295.1 - 6.7e-24 85.1 0.0 9.3e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF1769 PF08588.10 RKO96296.1 - 1.2e-19 70.3 0.3 2.5e-19 69.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) UQ_con PF00179.26 RKO96298.1 - 9.5e-49 164.6 0.0 1.1e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GATase PF00117.28 RKO96299.1 - 4.3e-37 127.7 0.0 8.7e-37 126.7 0.0 1.5 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 RKO96299.1 - 2.1e-11 43.7 0.0 4.8e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 RKO96299.1 - 1.2e-08 34.4 0.0 2.8e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 RKO96299.1 - 3.5e-08 33.5 0.0 1.3e-07 31.7 0.0 2.0 2 1 0 2 2 2 1 Peptidase C26 tRNA_Me_trans PF03054.16 RKO96299.1 - 0.001 17.9 0.1 0.0021 16.9 0.1 1.5 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 RKO96299.1 - 0.0038 16.7 0.0 0.016 14.7 0.0 1.8 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.19 RKO96299.1 - 0.0073 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 Arginosuccinate synthase PAPS_reduct PF01507.19 RKO96299.1 - 0.021 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ThiI PF02568.14 RKO96299.1 - 0.023 14.3 0.2 0.048 13.3 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) VID27 PF08553.10 RKO96301.1 - 1e-112 376.7 0.0 1.4e-112 376.3 0.0 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 RKO96301.1 - 0.036 14.3 0.1 0.083 13.2 0.1 1.6 1 0 0 1 1 1 0 VID27 PH-like domain AF-4 PF05110.13 RKO96301.1 - 1.3 7.0 7.0 1.7 6.6 7.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Trehalase PF01204.18 RKO96302.1 - 3.2e-97 326.5 0.0 4e-97 326.2 0.0 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_92 PF07971.12 RKO96302.1 - 0.0097 14.9 0.3 0.018 14.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 DUF4777 PF16007.5 RKO96302.1 - 0.09 13.0 0.0 0.7 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) PIP5K PF01504.18 RKO96305.1 - 6.5e-74 248.6 0.2 8.6e-74 248.2 0.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase GLTP PF08718.11 RKO96308.1 - 6.1e-46 156.4 0.0 7.5e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) DXP_reductoisom PF02670.16 RKO96308.1 - 0.043 14.5 0.1 0.065 14.0 0.1 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PALP PF00291.25 RKO96309.1 - 5.8e-43 147.4 0.2 1e-42 146.6 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme DUF4592 PF15262.6 RKO96309.1 - 0.18 12.5 2.0 0.35 11.6 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) Pentapeptide PF00805.22 RKO96309.1 - 0.22 11.2 0.2 4.3 7.1 0.0 2.2 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) UQ_con PF00179.26 RKO96312.1 - 1.3e-47 160.9 0.0 1.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKO96312.1 - 0.00023 20.9 0.0 0.00027 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RKO96312.1 - 0.027 14.7 1.5 0.033 14.5 1.5 1.5 1 1 0 1 1 1 0 RWD domain DUF483 PF04467.12 RKO96313.1 - 0.005 16.8 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF483) RNA_pol_Rpb2_1 PF04563.15 RKO96315.1 - 4.3e-67 225.6 0.0 5.4e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 RKO96315.1 - 1.3e-49 168.4 0.2 2.4e-48 164.3 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 RKO96315.1 - 3e-25 88.2 0.0 6.3e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RKO96315.1 - 6.2e-24 84.1 0.1 1.4e-23 82.9 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 Rotamase PF00639.21 RKO96316.1 - 6.9e-23 81.4 0.0 8.8e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 RKO96316.1 - 9.4e-18 64.8 0.0 1.2e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 RKO96316.1 - 4e-09 36.4 2.4 4.7e-09 36.2 0.7 1.9 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 RKO96316.1 - 5.9e-06 27.1 0.0 7.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain NDK PF00334.19 RKO96317.1 - 6e-38 129.9 0.0 6.7e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Macoilin PF09726.9 RKO96319.1 - 0.59 8.6 11.6 0.74 8.3 11.6 1.2 1 0 0 1 1 1 0 Macoilin family DUF966 PF06136.13 RKO96319.1 - 0.7 9.6 12.9 0.89 9.2 12.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 RKO96319.1 - 0.8 8.4 6.7 1.1 8.0 6.7 1.2 1 0 0 1 1 1 0 Presenilin Miff PF05644.11 RKO96319.1 - 1.6 8.2 8.2 2.2 7.8 8.2 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff NPR3 PF03666.13 RKO96319.1 - 4.6 5.9 7.6 5.7 5.6 7.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4551 PF15087.6 RKO96319.1 - 8 5.2 9.3 9.1 5.0 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PLDc PF00614.22 RKO96321.1 - 1.2e-07 31.6 0.1 4.8e-07 29.7 0.1 2.0 2 0 0 2 2 2 1 Phospholipase D Active site motif PLDc_2 PF13091.6 RKO96321.1 - 0.00019 21.4 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 PLD-like domain ECSCR PF15820.5 RKO96322.1 - 0.014 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator KA1 PF02149.19 RKO96323.1 - 2.8e-19 68.6 0.3 3.3e-19 68.4 0.3 1.1 1 0 0 1 1 1 1 Kinase associated domain 1 DUF1122 PF06557.11 RKO96324.1 - 0.069 12.6 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) ADH_zinc_N PF00107.26 RKO96324.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase eRF1_2 PF03464.15 RKO96325.1 - 3.6e-45 153.5 0.0 5.8e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 RKO96325.1 - 4.8e-38 130.1 0.1 9e-38 129.2 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 RKO96325.1 - 2.5e-19 69.5 0.0 4.2e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 RKO96325.1 - 1.2e-08 35.3 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 RKO96325.1 - 2.4e-08 34.4 0.0 3.8e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF5643 PF18705.1 RKO96325.1 - 0.0043 17.0 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5643) Nas2_N PF18265.1 RKO96326.1 - 3.2e-27 94.3 0.1 4.2e-27 93.9 0.1 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 RKO96326.1 - 1.7e-06 27.8 0.4 8.5e-05 22.3 0.4 2.7 1 1 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 RKO96326.1 - 0.004 17.4 0.0 0.082 13.2 0.0 2.3 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.14 RKO96326.1 - 0.0064 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Shisa PF13908.6 RKO96327.1 - 0.1 12.9 0.3 0.15 12.3 0.3 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PPTA PF01239.22 RKO96330.1 - 1.1e-17 63.2 8.9 1.3e-09 37.4 1.7 3.4 3 0 0 3 3 3 3 Protein prenyltransferase alpha subunit repeat CorA PF01544.18 RKO96332.1 - 0.0098 15.2 6.7 0.018 14.4 6.7 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF211 PF02680.14 RKO96332.1 - 0.11 12.7 0.7 9.3 6.5 0.0 3.3 3 1 0 3 3 3 0 Uncharacterized ArCR, COG1888 Baculo_PEP_C PF04513.12 RKO96332.1 - 0.46 10.5 4.7 0.57 10.2 0.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-DNL PF05180.12 RKO96333.1 - 1.7e-28 98.4 0.1 1.9e-28 98.2 0.1 1.0 1 0 0 1 1 1 1 DNL zinc finger ZZ PF00569.17 RKO96333.1 - 0.077 12.8 2.4 7.1 6.5 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type PHD PF00628.29 RKO96333.1 - 0.31 10.9 3.5 1.3 8.9 3.5 1.8 1 1 1 2 2 2 0 PHD-finger PIG-S PF10510.9 RKO96334.1 - 1.1e-46 159.8 0.5 1.5e-46 159.3 0.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein BRD4_CDT PF17105.5 RKO96334.1 - 0.34 10.5 2.7 0.71 9.5 2.7 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 Pkinase PF00069.25 RKO96335.1 - 1.6e-57 194.9 0.0 2e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96335.1 - 4.3e-31 108.1 0.0 5.3e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO96335.1 - 0.0001 21.7 0.0 0.027 13.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 RKO96335.1 - 0.00014 20.8 0.3 0.00038 19.3 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 RKO96335.1 - 0.00034 20.6 2.1 0.25 11.3 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RKO96335.1 - 0.0022 17.6 0.3 0.011 15.4 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 RKO96335.1 - 0.44 9.9 1.9 0.75 9.1 1.9 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WW PF00397.26 RKO96336.1 - 0.0021 18.1 2.6 0.0038 17.3 2.6 1.5 1 0 0 1 1 1 1 WW domain DUF1752 PF08550.10 RKO96337.1 - 0.00013 21.8 1.9 0.00021 21.1 1.9 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Peptidase_S10 PF00450.22 RKO96338.1 - 2.3e-70 238.1 0.0 2.7e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Lamprin PF06403.11 RKO96342.1 - 0.0039 17.1 2.3 0.0078 16.2 2.3 1.5 1 0 0 1 1 1 1 Lamprin Sporozoite_P67 PF05642.11 RKO96342.1 - 0.55 8.2 3.7 0.84 7.6 3.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DPPIV_N PF00930.21 RKO96343.1 - 2.8e-69 233.6 0.1 5.2e-52 176.7 0.0 3.0 3 0 0 3 3 3 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Pkinase PF00069.25 RKO96344.1 - 5.3e-62 209.6 0.0 6.1e-62 209.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96344.1 - 4.7e-47 160.4 0.0 5.5e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO96344.1 - 0.00029 20.3 0.0 0.0054 16.1 0.1 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 RKO96344.1 - 0.0015 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKO96344.1 - 0.0017 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 RKO96344.1 - 0.014 14.4 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 RKO96344.1 - 0.033 14.1 0.1 3 7.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sin3_corepress PF08295.12 RKO96345.1 - 4.2e-32 110.1 0.1 5.9e-32 109.7 0.1 1.2 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 RKO96346.1 - 2e-20 72.7 2.1 3e-20 72.1 2.1 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat VKG_Carbox PF05090.14 RKO96346.1 - 0.041 12.7 0.0 0.047 12.5 0.0 1.0 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase TMEM132D_C PF15706.5 RKO96347.1 - 0.15 11.9 1.0 0.35 10.7 1.0 1.6 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SKI PF01202.22 RKO96348.1 - 0.11 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Shikimate kinase V-ATPase_G PF03179.15 RKO96349.1 - 3e-23 82.4 14.9 3.7e-23 82.1 14.9 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit NIF PF03031.18 RKO96349.1 - 0.0077 16.0 0.0 0.0083 15.9 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PE PF00934.20 RKO96349.1 - 0.013 15.8 4.2 0.024 15.0 4.2 1.3 1 0 0 1 1 1 0 PE family BAR PF03114.18 RKO96350.1 - 6.9e-46 156.8 11.3 7.7e-46 156.7 11.3 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 RKO96350.1 - 2.7e-07 30.6 7.4 3.4e-07 30.2 7.4 1.3 1 1 0 1 1 1 1 BAR domain of APPL family Syntaxin_2 PF14523.6 RKO96350.1 - 0.03 14.7 6.0 0.49 10.8 3.3 2.8 2 1 0 2 2 2 0 Syntaxin-like protein Tn7_Tnp_TnsA_C PF08721.11 RKO96350.1 - 0.88 10.3 3.9 1.9 9.2 0.3 2.7 2 1 2 4 4 4 0 TnsA endonuclease C terminal FeoB_Cyto PF17910.1 RKO96350.1 - 1.7 9.2 7.0 1.6 9.3 5.0 2.0 1 1 1 2 2 2 0 FeoB cytosolic helical domain AAA_6 PF12774.7 RKO96352.1 - 2e-156 520.0 0.0 2.7e-156 519.6 0.0 1.2 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region Dynein_AAA_lid PF17852.1 RKO96352.1 - 9.1e-14 51.6 0.0 2.2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 RKO96352.1 - 6.3e-11 42.4 0.0 0.0038 17.2 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 RKO96352.1 - 0.0087 16.5 0.2 0.18 12.2 0.1 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RKO96352.1 - 0.023 15.1 0.8 0.63 10.5 0.0 2.9 3 0 0 3 3 3 0 RNA helicase AAA_16 PF13191.6 RKO96352.1 - 0.027 14.8 0.1 0.19 12.1 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 RKO96352.1 - 0.047 14.2 0.0 0.35 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 RKO96352.1 - 0.054 13.2 1.3 0.12 12.1 0.2 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RKO96352.1 - 0.1 12.9 0.1 8.3 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 RKO96352.1 - 0.23 10.0 0.6 3.7 6.0 0.0 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) DUF4554 PF15091.6 RKO96354.1 - 0.055 12.3 0.4 0.082 11.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) UCH PF00443.29 RKO96355.1 - 1e-22 80.9 0.0 1.9e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 RKO96355.1 - 1.7e-08 34.3 0.2 5e-08 32.7 0.2 1.9 1 0 0 1 1 1 1 A repeated domain in UCH-protein UCH_1 PF13423.6 RKO96355.1 - 0.12 12.0 0.1 0.35 10.4 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Acetyltransf_1 PF00583.25 RKO96356.1 - 3e-15 56.5 0.2 3.5e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 RKO96356.1 - 1.1e-10 41.3 0.1 1.4e-10 41.0 0.1 1.1 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 RKO96356.1 - 2.7e-10 40.2 0.0 3e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RKO96356.1 - 6.6e-10 39.3 0.1 7.6e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RKO96356.1 - 1.9e-06 27.6 0.0 2.3e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 RKO96356.1 - 1e-05 26.2 0.0 1.1e-05 26.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RKO96356.1 - 4.4e-05 23.6 0.1 5.4e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 RKO96356.1 - 0.0064 16.6 0.0 0.0068 16.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 RKO96356.1 - 0.011 15.9 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase LptE PF04390.12 RKO96356.1 - 0.16 12.7 0.0 0.18 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide-assembly WHEP-TRS PF00458.20 RKO96356.1 - 0.19 11.9 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 WHEP-TRS domain Cation_ATPase_C PF00689.21 RKO96357.1 - 3.8e-36 124.5 6.1 5.7e-36 123.9 6.1 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RKO96357.1 - 1.9e-19 70.8 0.8 3.5e-19 69.9 0.8 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RKO96357.1 - 2.7e-07 30.6 1.6 3.5e-05 23.7 1.1 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 RKO96357.1 - 0.012 16.0 0.1 0.025 15.0 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1440 PF07274.12 RKO96357.1 - 0.13 12.6 1.0 0.45 10.9 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) Abhydrolase_3 PF07859.13 RKO96358.1 - 6.1e-36 124.3 0.0 7.8e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 RKO96358.1 - 3.6e-09 36.0 0.0 4.7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 RKO96358.1 - 0.0078 15.1 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Hydrolase_4 PF12146.8 RKO96358.1 - 0.028 13.7 0.0 0.053 12.8 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 RKO96358.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Pex2_Pex12 PF04757.14 RKO96360.1 - 1.7e-05 24.5 0.2 2.1e-05 24.2 0.2 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Dpy-30 PF05186.13 RKO96361.1 - 1e-14 53.9 0.6 2.3e-14 52.8 0.6 1.6 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 RKO96361.1 - 4.4e-08 33.4 0.0 0.0051 16.9 0.0 3.6 3 0 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 RKO96361.1 - 0.00033 21.1 0.1 3.1 8.2 0.0 4.1 4 1 0 4 4 4 2 AAA domain Hydin_ADK PF17213.3 RKO96361.1 - 0.00059 20.2 0.2 0.0042 17.4 0.0 2.1 2 0 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 RKO96361.1 - 0.017 15.4 0.0 7.1 6.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain Sulphotransf PF09037.10 RKO96361.1 - 0.017 14.7 0.1 0.042 13.4 0.0 1.6 1 1 0 1 1 1 0 Stf0 sulphotransferase PRONE PF03759.13 RKO96361.1 - 0.055 12.3 0.3 0.088 11.6 0.3 1.2 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) AAA PF00004.29 RKO96361.1 - 0.072 13.5 0.2 0.39 11.1 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 RKO96361.1 - 0.12 12.5 0.5 1.2 9.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain DUF1800 PF08811.11 RKO96361.1 - 0.36 9.8 2.1 0.74 8.8 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1800) BAR PF03114.18 RKO96362.1 - 2.1e-46 158.5 1.3 2.5e-46 158.2 1.3 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 RKO96362.1 - 0.057 13.1 0.3 0.11 12.2 0.3 1.6 1 1 0 1 1 1 0 BAR domain of APPL family Sec34 PF04136.15 RKO96362.1 - 0.098 12.5 0.3 0.25 11.2 0.3 1.8 1 1 0 1 1 1 0 Sec34-like family Arfaptin PF06456.13 RKO96362.1 - 0.21 11.1 2.4 0.39 10.3 0.2 1.9 2 0 0 2 2 2 0 Arfaptin-like domain Hydrophobin PF01185.18 RKO96363.1 - 1.2e-05 25.8 9.9 3.4e-05 24.4 10.0 1.6 1 1 1 2 2 2 2 Fungal hydrophobin IPP-2 PF04979.14 RKO96364.1 - 1.5e-16 61.4 4.3 2.2e-11 44.6 4.3 2.6 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Rhabdo_ncap PF00945.18 RKO96365.1 - 0.18 10.6 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Alpha-amylase PF00128.24 RKO96367.1 - 6.1e-19 68.8 0.0 2.6e-17 63.4 0.0 2.1 2 0 0 2 2 2 2 Alpha amylase, catalytic domain Metallophos PF00149.28 RKO96368.1 - 2e-13 51.3 0.5 2.4e-13 51.0 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 RKO96368.1 - 2.5e-05 22.8 0.0 0.00015 20.2 0.0 2.0 2 0 0 2 2 2 1 Firmicute fructose-1,6-bisphosphatase PPR_3 PF13812.6 RKO96369.1 - 4.6e-08 33.0 0.0 0.00038 20.5 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 RKO96369.1 - 2.2e-06 27.8 0.0 0.0003 20.9 0.0 2.8 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 RKO96369.1 - 1.2e-05 25.2 0.7 0.073 13.4 0.0 3.8 4 0 0 4 4 4 2 PPR repeat TPR_14 PF13428.6 RKO96369.1 - 0.00068 20.3 2.1 13 6.9 0.1 5.5 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 RKO96369.1 - 0.017 15.6 1.4 11 6.6 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_1 PF12854.7 RKO96369.1 - 0.042 13.5 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 PPR repeat RVT_1 PF00078.27 RKO96370.1 - 0.00014 21.4 0.0 0.00027 20.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CASP_C PF08172.12 RKO96372.1 - 6.3e-43 146.9 0.3 7.2e-43 146.7 0.3 1.0 1 0 0 1 1 1 1 CASP C terminal GIT_CC PF16559.5 RKO96372.1 - 0.014 15.2 0.3 0.024 14.5 0.3 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CENP-H PF05837.12 RKO96372.1 - 0.017 15.5 0.3 0.026 14.9 0.3 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) bZIP_1 PF00170.21 RKO96372.1 - 0.11 12.7 0.9 0.11 12.7 0.9 1.9 2 0 0 2 2 2 0 bZIP transcription factor SlyX PF04102.12 RKO96372.1 - 0.35 11.5 2.3 3.7 8.2 0.4 2.3 1 1 1 2 2 2 0 SlyX WD40 PF00400.32 RKO96373.1 - 9.1e-10 39.0 0.1 2.9e-05 24.7 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO96373.1 - 0.0026 18.0 0.0 0.18 12.1 0.0 2.8 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain SWIRM PF04433.17 RKO96375.1 - 1e-17 64.3 0.0 2.1e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain HSP70 PF00012.20 RKO96376.1 - 4.4e-151 504.0 0.1 4.4e-151 504.0 0.1 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 RKO96376.1 - 1.2e-06 27.6 0.0 1.6e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Abhydrolase_9_N PF15420.6 RKO96377.1 - 0.067 13.2 5.6 0.13 12.2 5.6 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DALR_1 PF05746.15 RKO96380.1 - 5.5e-22 78.2 0.1 9e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 DALR anticodon binding domain tRNA-synt_1d PF00750.19 RKO96380.1 - 8.4e-19 67.7 0.1 1e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) Ribosomal_S6 PF01250.17 RKO96381.1 - 1.3e-13 51.0 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Svf1_C PF17187.4 RKO96381.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain Rho_N PF07498.12 RKO96381.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Peptidase_M43 PF05572.13 RKO96384.1 - 1.1e-16 61.0 0.0 1.6e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 RKO96384.1 - 0.00074 19.7 0.1 0.00083 19.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M7 PF02031.16 RKO96384.1 - 0.0026 17.9 0.1 0.006 16.7 0.1 1.6 1 0 0 1 1 1 1 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_3 PF13582.6 RKO96384.1 - 0.024 15.1 0.1 0.043 14.3 0.1 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 RKO96384.1 - 0.057 13.1 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 RKO96384.1 - 0.064 13.1 0.2 0.087 12.7 0.2 1.4 1 1 0 1 1 1 0 Matrixin DUF4953 PF16313.5 RKO96384.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Astacin PF01400.24 RKO96384.1 - 0.18 11.4 0.0 0.83 9.2 0.0 1.9 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) DnaJ PF00226.31 RKO96385.1 - 2.4e-16 59.6 0.0 3.7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Peptidase_M48_N PF16491.5 RKO96385.1 - 0.45 10.4 3.4 0.44 10.4 1.0 2.0 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices Fer2_BFD PF04324.15 RKO96386.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Glyco_transf_8 PF01501.20 RKO96389.1 - 3.3e-21 76.0 0.0 1.8e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 RKO96389.1 - 0.015 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative zinc_ribbon_10 PF10058.9 RKO96390.1 - 2.3e-19 68.8 0.3 3.8e-19 68.1 0.3 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein TPPK_C PF12555.8 RKO96391.1 - 0.18 11.9 0.3 0.36 10.9 0.3 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Utp12 PF04003.12 RKO96393.1 - 0.067 13.5 0.9 0.37 11.1 0.7 2.3 2 1 0 2 2 2 0 Dip2/Utp12 Family Phycobilisome PF00502.19 RKO96393.1 - 0.071 13.0 2.1 0.29 11.1 0.6 2.4 2 0 0 2 2 2 0 Phycobilisome protein Ten1_2 PF15490.6 RKO96395.1 - 6.9e-06 25.8 0.0 3.8e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit SSP160 PF06933.11 RKO96396.1 - 4.9 5.2 8.2 6.4 4.8 8.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 C12orf66_like PF09404.10 RKO96397.1 - 7.1e-18 64.7 0.0 1.1e-15 57.5 0.0 2.4 3 0 0 3 3 3 2 KICSTOR complex C12orf66 like DMPK_coil PF08826.10 RKO96398.1 - 0.0058 16.7 0.3 0.0058 16.7 0.3 3.2 3 0 0 3 3 3 1 DMPK coiled coil domain like DUF1846 PF08903.11 RKO96398.1 - 2.6 6.5 5.5 4.7 5.6 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1846) Baculo_PEP_C PF04513.12 RKO96398.1 - 4.4 7.3 12.4 9.1 6.3 0.3 3.5 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Solute_trans_a PF03619.16 RKO96399.1 - 9.8e-52 176.1 3.7 1.1e-51 175.9 3.7 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha tRNA-synt_1 PF00133.22 RKO96400.1 - 1.5e-36 125.9 2.1 9.7e-21 73.6 0.2 5.2 3 2 1 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RKO96400.1 - 8.1e-31 107.1 0.0 6.1e-23 81.2 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 RKO96400.1 - 0.00082 18.4 0.0 0.37 9.7 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (K) DNA_ligase_ZBD PF03119.16 RKO96400.1 - 0.024 14.7 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain tRNA-synt_1e PF01406.19 RKO96400.1 - 0.044 13.1 0.0 7.1 5.9 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain T2SSE PF00437.20 RKO96401.1 - 0.0072 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 RKO96401.1 - 0.015 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 KaiC CSN8_PSD8_EIF3K PF10075.9 RKO96402.1 - 2.9e-26 92.2 0.0 5e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 RKO96402.1 - 2.1e-06 27.4 1.3 2.7e-06 27.0 1.3 1.1 1 0 0 1 1 1 1 SAC3/GANP family Helicase_C PF00271.31 RKO96404.1 - 4.2e-17 62.5 0.0 1.7e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKO96404.1 - 1.3e-14 54.4 0.0 2.3e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 RKO96404.1 - 1.1e-07 32.5 0.3 4.8e-07 30.4 0.0 2.1 2 0 0 2 2 2 1 RecQ zinc-binding Ribosomal_L18A PF01775.17 RKO96405.1 - 5.4e-53 178.2 0.6 6.6e-53 177.9 0.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PGM_PMM_I PF02878.16 RKO96407.1 - 8.7e-36 122.7 0.1 1.5e-35 121.9 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 RKO96407.1 - 1.2e-27 96.3 0.0 3.1e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 RKO96407.1 - 1.9e-15 57.3 0.0 4.9e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 RKO96407.1 - 2.9e-07 30.6 0.0 7.9e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF4466 PF14725.6 RKO96407.1 - 0.19 11.2 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4466) Pkinase PF00069.25 RKO96408.1 - 3.5e-70 236.4 0.0 4.1e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96408.1 - 2.2e-36 125.5 0.0 2.5e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO96408.1 - 1.3e-06 28.0 0.0 1.3e-05 24.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKO96408.1 - 0.00021 20.3 0.0 0.00046 19.2 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 RKO96408.1 - 0.00069 19.3 0.0 0.00095 18.8 0.0 1.1 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 RKO96408.1 - 0.00098 18.8 0.2 0.17 11.5 0.0 2.1 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKO96408.1 - 0.0013 18.7 0.1 0.0042 17.0 0.0 1.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RKO96408.1 - 0.032 13.6 0.2 0.059 12.7 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 RKO96408.1 - 0.047 12.5 0.2 0.085 11.6 0.1 1.4 1 1 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 RKO96408.1 - 0.068 12.8 0.2 1.6 8.2 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 RKO96408.1 - 0.13 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 MPC PF03650.13 RKO96409.1 - 3e-30 104.6 0.2 3.1e-30 104.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Thioredoxin PF00085.20 RKO96410.1 - 3.8e-27 94.3 0.1 6e-26 90.4 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 RKO96410.1 - 0.0002 21.7 0.0 0.00059 20.1 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 RKO96410.1 - 0.00022 21.6 0.1 0.11 13.0 0.1 2.6 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.21 RKO96410.1 - 0.00025 21.0 0.0 0.00036 20.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 RKO96410.1 - 0.0013 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 RKO96410.1 - 0.005 16.7 0.0 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 RKO96410.1 - 0.0085 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin SNF2_N PF00176.23 RKO96411.1 - 5.7e-71 239.1 0.0 7.1e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Ham1p_like PF01725.16 RKO96412.1 - 9.7e-52 175.6 0.0 1.1e-51 175.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Fez1 PF06818.15 RKO96413.1 - 2 8.8 40.8 1 9.8 4.8 4.1 1 1 1 3 3 3 0 Fez1 DUF812 PF05667.11 RKO96413.1 - 8.4 5.1 44.0 1.7 7.5 26.3 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF812) Helicase_C PF00271.31 RKO96414.1 - 0.031 14.6 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Ribosomal_L27e PF01777.18 RKO96415.1 - 2.5e-27 95.0 3.4 3.4e-27 94.6 3.4 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 RKO96415.1 - 0.00024 20.9 0.1 0.00067 19.5 0.1 1.7 1 0 0 1 1 1 1 KOW motif Nas2_N PF18265.1 RKO96416.1 - 0.016 15.1 0.7 0.016 15.1 0.7 4.7 4 0 0 4 4 4 0 Nas2 N_terminal domain IFP_35_N PF07334.13 RKO96416.1 - 0.017 15.2 0.0 0.017 15.2 0.0 4.7 5 0 0 5 5 5 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TSC22 PF01166.18 RKO96416.1 - 7.7 6.9 13.3 1.8 8.9 0.2 4.7 4 0 0 4 4 4 0 TSC-22/dip/bun family AAA_16 PF13191.6 RKO96417.1 - 0.0022 18.4 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ORF6N PF10543.9 RKO96417.1 - 0.045 14.0 0.0 31 4.9 0.0 3.5 3 0 0 3 3 3 0 ORF6N domain AAA_19 PF13245.6 RKO96417.1 - 0.08 13.3 0.9 3.8 7.8 0.0 2.6 1 1 1 2 2 2 0 AAA domain TPR_12 PF13424.6 RKO96417.1 - 0.43 10.9 5.6 20 5.6 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Asp PF00026.23 RKO96418.1 - 1.9e-109 365.9 0.5 2.2e-109 365.7 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RKO96418.1 - 8.6e-13 48.9 1.0 1.8e-09 38.1 0.6 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RKO96418.1 - 6.1e-06 26.1 0.0 0.00019 21.3 0.0 2.4 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 RKO96418.1 - 0.0029 18.2 0.3 0.99 10.1 0.1 2.8 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 RKO96418.1 - 0.012 16.2 0.0 4.6 7.9 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease C2 PF00168.30 RKO96421.1 - 5.5e-07 29.8 0.0 8.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain THDPS_N_2 PF14805.6 RKO96422.1 - 0.16 12.2 1.4 0.35 11.1 1.4 1.6 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal LRR_8 PF13855.6 RKO96424.1 - 1e-21 76.4 2.5 2.1e-10 40.2 0.4 2.3 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RKO96424.1 - 4.5e-16 58.7 2.3 0.0001 22.6 0.0 3.3 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 RKO96424.1 - 3e-10 39.2 0.8 2.5 9.0 0.0 5.2 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.6 RKO96424.1 - 2.2e-07 30.4 5.7 0.7 10.1 0.1 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 RKO96424.1 - 0.00089 18.8 0.5 0.25 10.8 0.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat MSP1_C PF07462.11 RKO96425.1 - 2.2 6.9 5.8 2.9 6.5 5.8 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PsbQ PF05757.11 RKO96425.1 - 4.1 7.1 7.7 9.2 5.9 7.7 1.6 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) SCP2 PF02036.17 RKO96426.1 - 2.4e-25 88.9 0.5 2.8e-25 88.7 0.5 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 RKO96426.1 - 6.6e-06 26.4 0.2 8.2e-06 26.1 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal UQ_con PF00179.26 RKO96427.1 - 2.1e-41 140.9 0.0 2.3e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKO96427.1 - 0.00064 19.4 0.0 0.0008 19.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 RKO96427.1 - 0.042 13.7 0.0 0.079 12.8 0.0 1.5 1 1 0 1 1 1 0 UEV domain tRNA_anti-codon PF01336.25 RKO96428.1 - 0.00097 19.1 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HSF_DNA-bind PF00447.17 RKO96429.1 - 8.8e-31 106.4 0.4 1e-30 106.2 0.4 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 RKO96429.1 - 0.0032 17.9 0.0 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 Ets-domain DnaB_2 PF07261.11 RKO96430.1 - 0.17 11.7 0.0 0.73 9.6 0.0 2.1 2 0 0 2 2 2 0 Replication initiation and membrane attachment Mito_carr PF00153.27 RKO96431.1 - 2.1e-26 91.7 5.0 2.1e-12 46.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein YjcB PF15940.5 RKO96431.1 - 0.044 13.9 0.2 0.46 10.7 0.0 2.4 3 0 0 3 3 3 0 Family of unknown function DUF2892 PF11127.8 RKO96431.1 - 9.4 6.4 7.0 5.5 7.1 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Guanylate_cyc PF00211.20 RKO96432.1 - 1.3e-16 60.8 0.1 4.4e-09 36.2 0.0 2.2 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DinB_2 PF12867.7 RKO96435.1 - 3.6 8.1 6.9 4.6 7.8 6.3 1.7 1 1 0 1 1 1 0 DinB superfamily Gtr1_RagA PF04670.12 RKO96436.1 - 1.1e-100 335.8 0.0 1.3e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 RKO96436.1 - 1.8e-09 37.8 0.0 4.7e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 RKO96436.1 - 2.7e-08 33.6 0.0 6.4e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Ras family Arf PF00025.21 RKO96436.1 - 2.6e-07 30.3 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKO96436.1 - 4.8e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 RKO96436.1 - 0.0096 15.5 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 RKO96436.1 - 0.05 14.1 0.0 0.088 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.10 RKO96436.1 - 0.052 13.0 0.0 0.075 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 RKO96436.1 - 0.068 12.3 4.3 0.83 8.7 0.0 2.6 2 1 1 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.9 RKO96436.1 - 0.07 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RKO96436.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RKO96436.1 - 0.15 12.0 0.1 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Aminotran_4 PF01063.19 RKO96437.1 - 1.3e-11 44.8 0.0 1.5e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Polysacc_deac_1 PF01522.21 RKO96438.1 - 2.1e-33 114.9 0.0 3e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 RKO96438.1 - 0.00023 20.5 0.0 0.00028 20.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2373 PF10180.9 RKO96439.1 - 1.4e-11 44.0 0.0 2.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Red1 PF07964.11 RKO96439.1 - 0.16 10.2 13.2 0.19 9.9 13.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Med19 PF10278.9 RKO96439.1 - 1.5 8.7 22.7 0.6 10.0 20.0 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Presenilin PF01080.17 RKO96439.1 - 5.9 5.5 10.8 8.4 5.0 10.8 1.2 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 RKO96439.1 - 7.6 6.0 12.6 11 5.6 12.6 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Eapp_C PF10238.9 RKO96439.1 - 9.5 6.3 14.7 14 5.8 10.1 2.1 2 0 0 2 2 2 0 E2F-associated phosphoprotein CLZ PF16526.5 RKO96440.1 - 0.066 13.6 4.5 0.15 12.5 0.0 3.3 3 1 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF713 PF05218.14 RKO96440.1 - 0.44 10.3 3.7 0.34 10.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF713) XPG_N PF00752.17 RKO96441.1 - 9.1e-16 58.2 0.0 9.6e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 XPG N-terminal domain Mito_carr PF00153.27 RKO96442.1 - 3.6e-56 187.1 0.1 1.1e-18 67.0 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-CCCH PF00642.24 RKO96443.1 - 3.7e-18 65.0 35.6 6.9e-06 25.8 0.3 5.2 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 RKO96443.1 - 4.3e-15 55.2 38.3 1.1e-06 28.4 1.9 5.9 5 1 0 5 5 5 5 Zinc finger domain Torus PF16131.5 RKO96443.1 - 9.9e-11 42.3 28.0 0.00013 22.6 0.6 5.1 1 1 4 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 RKO96443.1 - 1.3e-07 31.2 34.7 8.3e-06 25.5 0.4 4.9 5 0 0 5 5 5 3 CCCH-type zinc finger zf-CCCH_3 PF15663.5 RKO96443.1 - 2.7e-07 30.8 26.6 1.3e-05 25.4 9.9 3.3 1 1 2 3 3 3 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 RKO96443.1 - 1.6e-05 25.2 30.7 0.02 15.4 0.2 5.7 5 1 0 5 5 5 4 RNA-binding, Nab2-type zinc finger RRM_1 PF00076.22 RKO96444.1 - 2.2e-19 69.0 0.0 2.6e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO96444.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif ATG22 PF11700.8 RKO96445.1 - 3.5e-73 246.9 22.7 4.2e-73 246.6 22.7 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like PH PF00169.29 RKO96446.1 - 0.023 15.2 0.0 9.4 6.8 0.0 2.4 2 1 0 2 2 2 0 PH domain DUF5098 PF17023.5 RKO96446.1 - 0.031 13.3 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5098) PH PF00169.29 RKO96447.1 - 9.3e-09 35.7 0.0 2.4e-08 34.5 0.0 1.7 2 0 0 2 2 2 1 PH domain FCH PF00611.23 RKO96447.1 - 0.00017 21.8 0.1 0.00078 19.7 0.0 2.2 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain KRE1 PF17056.5 RKO96447.1 - 0.068 12.9 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Killer toxin-resistance protein 1 T3SSipB PF16535.5 RKO96447.1 - 0.72 10.3 6.5 0.33 11.4 2.9 1.9 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF2385 PF09539.10 RKO96447.1 - 3.4 8.2 7.3 0.21 12.1 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) DEAD PF00270.29 RKO96452.1 - 1.2e-50 171.8 0.0 2e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO96452.1 - 1.1e-29 103.1 0.0 1.2e-28 99.6 0.0 2.6 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO96452.1 - 6.1e-05 23.1 0.0 0.00012 22.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RKO96452.1 - 0.0012 19.2 0.0 0.021 15.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain CMS1 PF14617.6 RKO96452.1 - 0.015 14.6 0.0 0.035 13.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 RKO96452.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase PAC2 PF09754.9 RKO96452.1 - 0.021 14.8 0.0 0.059 13.4 0.0 1.8 1 1 0 1 1 1 0 PAC2 family AAA_30 PF13604.6 RKO96452.1 - 0.024 14.4 0.0 0.14 11.8 0.0 2.2 2 2 0 2 2 2 0 AAA domain Glyco_hydro_26 PF02156.15 RKO96453.1 - 5.9e-06 25.9 0.9 0.00013 21.5 0.1 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 RRM_1 PF00076.22 RKO96454.1 - 2.4e-79 261.2 0.3 3.4e-19 68.4 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKO96454.1 - 3.9e-10 39.4 0.0 0.0013 18.4 0.0 3.4 2 2 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO96454.1 - 1.3e-06 28.4 0.0 1.2 9.3 0.0 4.5 4 1 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 RKO96454.1 - 0.00043 20.1 0.0 0.024 14.5 0.0 2.8 3 0 0 3 3 3 1 Occluded RNA-recognition motif DUF4523 PF15023.6 RKO96454.1 - 0.00094 19.0 0.0 1.2 9.0 0.0 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF4523) RRM_3 PF08777.11 RKO96454.1 - 0.0016 18.5 0.7 1.5 8.9 0.2 3.7 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM_2 PF14605.6 RKO96454.1 - 0.014 15.4 0.2 11 6.1 0.0 3.5 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 RKO96454.1 - 0.023 14.4 3.1 5 6.9 0.0 3.4 3 0 0 3 3 3 0 Ribonuclease B OB domain LPMO_10 PF03067.15 RKO96456.1 - 1.2e-10 42.3 1.5 3.2e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 RKO96456.1 - 0.0042 17.0 0.7 0.015 15.2 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 SOG2 PF10428.9 RKO96456.1 - 6.3 5.9 24.2 10 5.2 24.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein NAD_binding_10 PF13460.6 RKO96457.1 - 3.4e-11 43.4 0.3 6e-11 42.6 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 RKO96457.1 - 1.4e-09 37.8 0.0 6.2e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 RKO96457.1 - 1e-08 35.1 0.0 1.4e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 RKO96457.1 - 1.3e-07 30.9 0.0 2.9e-07 29.8 0.0 1.5 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 RKO96457.1 - 9.1e-07 28.2 0.4 0.0097 15.0 0.0 2.4 3 0 0 3 3 3 2 RmlD substrate binding domain NAD_binding_4 PF07993.12 RKO96457.1 - 2.4e-05 23.6 0.1 0.92 8.6 0.0 3.0 2 1 1 3 3 3 3 Male sterility protein Polysacc_synt_2 PF02719.15 RKO96457.1 - 0.054 12.6 0.0 0.082 12.0 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 RKO96457.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ParcG PF10274.9 RKO96458.1 - 2.2e-78 262.6 0.0 2.5e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 RKO96458.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 MMS19_C PF12460.8 RKO96458.1 - 0.087 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal TPR_1 PF00515.28 RKO96459.1 - 5.6e-15 54.4 10.4 4e-06 26.4 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RKO96459.1 - 2.2e-14 52.9 8.6 6.4e-06 25.8 2.2 3.1 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.17 RKO96459.1 - 4.1e-14 51.5 10.4 7.6e-05 22.5 0.1 3.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RKO96459.1 - 4.8e-11 42.0 8.2 1.3e-05 25.0 0.1 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 RKO96459.1 - 2.8e-09 37.0 0.4 2.3e-05 24.4 0.1 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKO96459.1 - 5.8e-08 33.1 4.7 2.1e-05 25.0 1.7 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO96459.1 - 7.2e-08 33.0 6.8 2.4e-05 24.9 3.5 2.2 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 RKO96459.1 - 1.2e-07 32.0 3.2 0.011 16.5 0.1 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 RKO96459.1 - 7.7e-07 29.1 5.9 1.5e-05 25.0 0.2 2.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_20 PF14561.6 RKO96459.1 - 0.001 19.4 0.8 0.0066 16.8 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKO96459.1 - 0.0012 19.1 7.5 0.36 11.1 3.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKO96459.1 - 0.073 13.1 1.3 11 6.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO96459.1 - 0.1 12.8 5.1 0.14 12.4 4.7 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 RKO96459.1 - 0.2 12.1 1.4 0.97 9.9 0.3 2.0 1 1 0 1 1 1 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 RKO96459.1 - 0.26 12.0 6.9 0.28 11.9 0.4 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat Holin_9 PF16936.5 RKO96461.1 - 0.078 13.2 0.1 0.091 12.9 0.1 1.1 1 0 0 1 1 1 0 Putative holin AAA PF00004.29 RKO96462.1 - 6.1e-38 130.2 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO96462.1 - 1.9e-07 30.8 1.1 4.1e-07 29.7 0.0 2.1 3 0 0 3 3 1 1 AAA+ lid domain AAA_5 PF07728.14 RKO96462.1 - 9.7e-07 28.9 0.1 5.4e-06 26.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 RKO96462.1 - 3.8e-06 26.7 0.0 9.6e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 RKO96462.1 - 1.4e-05 25.0 0.0 0.00013 21.9 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 RKO96462.1 - 2.6e-05 24.5 2.7 0.0034 17.6 0.9 3.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 RKO96462.1 - 0.00013 22.4 4.8 0.036 14.4 0.1 3.1 1 1 2 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 RKO96462.1 - 0.00024 20.4 0.0 0.00038 19.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 RKO96462.1 - 0.00038 20.6 0.1 0.00073 19.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 RKO96462.1 - 0.00063 19.9 0.0 0.0025 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 RKO96462.1 - 0.0019 18.0 0.2 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 RKO96462.1 - 0.0053 16.2 1.0 0.018 14.4 0.2 2.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 RKO96462.1 - 0.0056 16.1 0.1 11 5.3 0.0 3.1 2 1 0 3 3 3 0 Bacterial TniB protein AAA_25 PF13481.6 RKO96462.1 - 0.017 14.7 3.8 0.11 12.1 0.2 2.9 1 1 2 3 3 3 0 AAA domain TsaE PF02367.17 RKO96462.1 - 0.019 14.9 0.1 0.034 14.2 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 RKO96462.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 RKO96462.1 - 0.031 14.0 0.0 3.8 7.2 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_21 PF13304.6 RKO96462.1 - 0.032 14.0 0.3 0.14 12.0 0.0 2.0 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_14 PF13173.6 RKO96462.1 - 0.044 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RKO96462.1 - 0.062 13.7 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 RKO96462.1 - 0.07 12.6 0.1 0.23 11.0 0.2 1.8 2 1 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 RKO96462.1 - 0.086 12.2 0.3 1.9 7.8 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.6 RKO96462.1 - 0.1 13.1 0.4 0.2 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 RKO96462.1 - 0.12 12.1 0.2 0.3 10.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RKO96462.1 - 0.27 11.1 0.9 1.9 8.3 0.5 2.2 2 0 0 2 2 2 0 NACHT domain DUF1126 PF06565.12 RKO96464.1 - 1e-64 214.9 0.0 3.6e-30 103.9 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain GIY-YIG PF01541.24 RKO96465.1 - 0.0035 17.6 0.0 0.056 13.7 0.0 2.3 2 0 0 2 2 2 1 GIY-YIG catalytic domain SET_assoc PF11767.8 RKO96465.1 - 0.084 12.5 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 Histone lysine methyltransferase SET associated DUF1970 PF09301.10 RKO96466.1 - 0.059 13.6 0.7 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) ADP_PFK_GK PF04587.15 RKO96466.1 - 0.078 11.5 3.4 0.098 11.2 2.9 1.3 1 1 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region RRM_1 PF00076.22 RKO96467.1 - 2.3e-15 56.2 0.0 3.8e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RKO96467.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ThiF PF00899.21 RKO96468.1 - 3.9e-18 65.7 0.0 4.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family VWA_3 PF13768.6 RKO96468.1 - 0.076 13.0 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain ETF PF01012.21 RKO96470.1 - 1.5e-47 161.9 1.8 1.8e-47 161.6 1.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Clathrin PF00637.20 RKO96471.1 - 8.5e-94 311.0 7.0 4.5e-28 97.9 0.2 4.7 5 0 0 5 5 5 4 Region in Clathrin and VPS Clathrin_H_link PF13838.6 RKO96471.1 - 2.3e-30 104.3 0.4 1.5e-29 101.7 0.1 2.4 3 0 0 3 3 3 1 Clathrin-H-link Clathrin_propel PF01394.20 RKO96471.1 - 5.8e-23 80.0 0.0 1.5e-05 25.1 0.0 4.5 4 0 0 4 4 4 4 Clathrin propeller repeat Clathrin-link PF09268.10 RKO96471.1 - 4.3e-12 45.2 0.4 9.6e-12 44.0 0.4 1.7 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Syntaxin-6_N PF09177.11 RKO96472.1 - 1.2e-18 67.5 0.4 6.3e-18 65.2 0.1 2.1 1 1 1 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 RKO96472.1 - 9e-08 32.0 3.2 9e-08 32.0 3.2 2.6 3 1 1 4 4 4 1 SNARE domain DUF3135 PF11333.8 RKO96472.1 - 0.00088 19.5 1.4 0.0016 18.6 1.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3135) Use1 PF09753.9 RKO96472.1 - 0.0015 18.4 2.0 0.0016 18.2 2.0 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF745 PF05335.13 RKO96472.1 - 0.0025 17.6 2.8 0.0025 17.6 2.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF745) Uso1_p115_C PF04871.13 RKO96472.1 - 0.0067 16.8 1.1 0.0099 16.2 0.8 1.4 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Prominin PF05478.11 RKO96472.1 - 0.017 13.1 1.7 0.021 12.8 1.7 1.2 1 0 0 1 1 1 0 Prominin DUF1054 PF06335.12 RKO96472.1 - 0.048 13.6 0.3 0.065 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) MFS_Mycoplasma PF07672.13 RKO96472.1 - 0.093 12.0 3.3 0.15 11.3 3.3 1.3 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF2207 PF09972.9 RKO96472.1 - 0.1 11.3 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) EMP24_GP25L PF01105.24 RKO96472.1 - 0.47 10.4 7.4 1.5 8.7 2.6 2.7 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Pox_EPC_I2-L1 PF12575.8 RKO96472.1 - 0.52 10.6 2.8 0.76 10.1 1.2 2.0 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 SlyX PF04102.12 RKO96472.1 - 5.3 7.7 14.5 1.8 9.3 6.8 3.2 3 1 1 4 4 4 0 SlyX TB2_DP1_HVA22 PF03134.19 RKO96474.1 - 4.5e-12 45.7 2.1 4.5e-12 45.7 2.1 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family SUI1 PF01253.22 RKO96475.1 - 6.1e-25 87.5 0.1 8.6e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 AC_N PF16214.5 RKO96476.1 - 0.7 9.0 2.5 0.75 8.8 2.5 1.1 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Herpes_US9 PF06072.11 RKO96476.1 - 1.6 8.7 4.9 0.61 10.0 0.9 2.2 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 ATP-synt_D PF01813.17 RKO96477.1 - 1.5e-73 246.8 1.0 2.2e-73 246.3 1.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit D DUF4300 PF14133.6 RKO96477.1 - 0.0069 16.1 0.0 0.0092 15.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4300) EF-G-binding_N PF07299.11 RKO96477.1 - 0.036 14.6 0.8 0.1 13.1 0.8 1.8 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal NPV_P10 PF05531.12 RKO96477.1 - 0.37 11.3 1.9 25 5.4 0.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ca_bind_SSO6904 PF18249.1 RKO96477.1 - 7.7 7.0 6.9 28 5.2 0.9 3.3 2 1 1 3 3 3 0 Calcium binding protein SSO6904 ELO PF01151.18 RKO96478.1 - 2.8e-55 187.6 9.6 3.1e-55 187.4 9.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family AAA PF00004.29 RKO96479.1 - 3.8e-63 211.8 0.0 2.1e-43 147.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO96479.1 - 3.3e-14 52.4 10.3 3.5e-11 42.7 0.4 3.1 3 0 0 3 3 3 2 AAA+ lid domain RuvB_N PF05496.12 RKO96479.1 - 1.8e-08 34.3 0.0 0.00014 21.7 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RKO96479.1 - 1.8e-08 34.9 9.8 0.0014 19.1 0.0 4.5 2 2 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 RKO96479.1 - 5e-08 33.0 0.0 0.00062 19.8 0.0 3.2 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RKO96479.1 - 2.2e-07 31.1 0.0 0.0016 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RKO96479.1 - 1e-05 25.7 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 RKO96479.1 - 1.1e-05 25.8 0.0 0.14 12.4 0.0 3.4 2 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 RKO96479.1 - 5.1e-05 23.6 0.0 0.33 11.4 0.0 2.5 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 RKO96479.1 - 0.0001 22.1 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 RKO96479.1 - 0.00019 21.4 0.1 0.59 10.0 0.0 3.7 3 1 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 RKO96479.1 - 0.0004 19.8 0.2 0.21 10.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 RKO96479.1 - 0.00049 19.4 0.0 0.0067 15.7 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 RKO96479.1 - 0.0022 17.6 0.9 2.8 7.5 0.1 3.3 3 1 1 4 4 4 2 AAA domain AAA_7 PF12775.7 RKO96479.1 - 0.0028 17.2 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 RKO96479.1 - 0.0031 17.4 0.0 0.044 13.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain TsaE PF02367.17 RKO96479.1 - 0.0067 16.4 0.0 2.8 8.0 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 RKO96479.1 - 0.0081 16.4 0.0 0.77 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 RKO96479.1 - 0.0098 15.6 0.0 1.3 8.7 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 RKO96479.1 - 0.018 15.1 0.0 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RKO96479.1 - 0.02 14.6 0.0 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 RKO96479.1 - 0.029 14.5 0.0 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.16 RKO96479.1 - 0.032 13.1 0.0 0.5 9.2 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_3 PF07726.11 RKO96479.1 - 0.082 12.8 0.0 0.99 9.3 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hpr_kinase_C PF07475.12 RKO96479.1 - 0.13 11.8 0.1 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 RKO96479.1 - 0.15 12.6 0.0 31 5.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter DAP3 PF10236.9 RKO96479.1 - 0.17 11.0 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 MFS_5 PF05631.14 RKO96481.1 - 0.015 14.2 0.2 0.017 14.1 0.2 1.0 1 0 0 1 1 1 0 Sugar-tranasporters, 12 TM MHYT PF03707.16 RKO96481.1 - 0.018 15.2 2.5 0.52 10.5 0.2 2.3 2 1 0 2 2 2 0 Bacterial signalling protein N terminal repeat Nop16 PF09420.10 RKO96483.1 - 1.6e-10 41.4 0.6 1.6e-10 41.4 0.6 1.8 1 1 0 2 2 2 1 Ribosome biogenesis protein Nop16 UBA PF00627.31 RKO96484.1 - 0.02 14.8 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 UBA/TS-N domain XPG_I PF00867.18 RKO96486.1 - 3.1e-30 104.4 0.0 6.3e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 RKO96486.1 - 2.1e-22 79.5 0.0 4.2e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 RKO96486.1 - 0.00018 22.1 0.0 0.00051 20.6 0.0 1.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 RKO96486.1 - 0.0013 19.3 0.0 0.0025 18.4 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Proteasome PF00227.26 RKO96487.1 - 2.1e-28 99.1 0.0 2.5e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Arabino_trans_N PF17689.1 RKO96488.1 - 0.02 15.1 2.0 0.026 14.7 2.0 1.3 1 0 0 1 1 1 0 Arabinosyltransferase concanavalin like domain Rib_recp_KP_reg PF05104.12 RKO96488.1 - 5.1 8.1 8.1 7.2 7.6 8.1 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region LRR_6 PF13516.6 RKO96489.1 - 2.2e-14 52.2 15.4 1.6e-05 24.6 0.2 6.1 6 0 0 6 6 6 5 Leucine Rich repeat LRR_1 PF00560.33 RKO96489.1 - 0.00014 21.9 0.0 15 6.6 0.0 4.6 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.7 RKO96489.1 - 0.00072 19.9 0.7 0.17 12.4 0.1 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO96489.1 - 0.045 13.5 6.6 3.7 7.4 0.3 2.9 1 1 1 2 2 2 0 Leucine rich repeat Med15_fungi PF05397.12 RKO96490.1 - 6.5e-11 42.5 0.0 6.5e-11 42.5 0.0 5.1 4 2 1 5 5 5 1 Mediator complex subunit 15 Gti1_Pac2 PF09729.9 RKO96490.1 - 2.6 8.1 28.0 10 6.2 3.7 3.4 3 0 0 3 3 3 0 Gti1/Pac2 family eIF-3_zeta PF05091.12 RKO96490.1 - 4.4 6.2 43.5 0.88 8.5 11.3 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PTPRCAP PF15713.5 RKO96490.1 - 6.4 7.0 32.9 4 7.7 10.1 3.5 3 0 0 3 3 3 0 Protein tyrosine phosphatase receptor type C-associated CTNNBL PF08216.11 RKO96491.1 - 7.2e-19 67.9 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear VWA_2 PF13519.6 RKO96493.1 - 9.6e-05 23.0 0.0 0.0002 21.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF1242 PF06842.12 RKO96494.1 - 3.7e-20 71.4 1.5 4.8e-20 71.1 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Mucin PF01456.17 RKO96495.1 - 8.6e-06 25.8 24.5 8.6e-06 25.8 24.5 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein MGC-24 PF05283.11 RKO96495.1 - 0.29 11.6 11.9 0.57 10.6 11.9 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AJAP1_PANP_C PF15298.6 RKO96495.1 - 3.4 7.8 17.4 7.3 6.8 17.4 1.5 1 0 0 1 1 1 0 AJAP1/PANP C-terminus WD40 PF00400.32 RKO96497.1 - 3e-18 65.8 2.6 0.00018 22.2 0.0 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO96497.1 - 4.9e-06 26.8 0.0 0.091 13.1 0.0 3.5 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO96497.1 - 0.00011 21.0 0.0 0.28 9.8 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKO96497.1 - 0.002 17.2 0.3 1.7 7.5 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 RKO96497.1 - 0.11 11.6 0.2 0.95 8.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) AlaDh_PNT_N PF05222.15 RKO96498.1 - 1.4e-25 90.1 0.0 3.1e-25 89.1 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DEP PF00610.21 RKO96498.1 - 0.092 12.8 0.0 1.6 8.8 0.0 2.5 3 0 0 3 3 3 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) IBN_N PF03810.19 RKO96499.1 - 1.9e-19 69.4 0.1 1.2e-17 63.5 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 RKO96499.1 - 1.6e-05 24.0 0.0 5.9e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Cse1 Xpo1 PF08389.12 RKO96499.1 - 2.1 8.4 5.4 5.6 7.0 0.0 3.9 4 2 1 5 5 5 0 Exportin 1-like protein DUF4490 PF14892.6 RKO96501.1 - 1.9e-15 56.8 0.1 1.9e-15 56.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) WD40 PF00400.32 RKO96503.1 - 4.6e-70 229.8 22.7 5.3e-09 36.6 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO96503.1 - 1.7e-21 76.3 0.7 0.002 18.4 0.0 5.5 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO96503.1 - 8.8e-08 31.5 0.1 0.015 14.3 0.0 3.9 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RKO96503.1 - 3.3e-05 23.9 0.0 0.65 9.9 0.0 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 RKO96503.1 - 6.1e-05 21.9 7.9 1.5 7.4 0.0 4.7 3 2 2 5 5 5 3 Nucleoporin Nup120/160 Frtz PF11768.8 RKO96503.1 - 7.8e-05 21.2 0.0 0.19 10.0 0.0 2.1 2 0 0 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz Nbas_N PF15492.6 RKO96503.1 - 0.0046 16.3 0.4 1.7 7.9 0.0 3.2 3 2 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 RKO96503.1 - 0.019 13.5 0.0 0.82 8.1 0.0 2.7 2 1 1 3 3 3 0 Cytochrome D1 heme domain FAD_binding_9 PF08021.11 RKO96503.1 - 0.037 14.3 0.0 0.1 12.8 0.0 1.7 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain WD40_like PF17005.5 RKO96503.1 - 0.043 13.1 0.0 7.6 5.8 0.0 3.2 3 0 0 3 3 3 0 WD40-like domain PD40 PF07676.12 RKO96503.1 - 0.058 13.3 6.2 3.8 7.6 0.1 3.9 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 RKO96503.1 - 0.54 10.0 2.1 17 5.2 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature zf-C3HC4_4 PF15227.6 RKO96504.1 - 1.7e-06 28.1 6.8 3.5e-06 27.1 6.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 RKO96504.1 - 0.00028 20.8 8.2 0.00028 20.8 8.2 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RKO96504.1 - 0.0012 18.6 7.4 0.0042 16.9 7.5 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 RKO96504.1 - 0.0018 18.2 7.3 0.0048 16.8 7.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 RKO96504.1 - 0.0044 16.8 3.7 0.012 15.4 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKO96504.1 - 0.0055 16.6 8.4 0.0055 16.6 8.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKO96504.1 - 0.034 14.0 4.1 0.077 12.9 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 RKO96504.1 - 0.1 13.0 7.0 0.29 11.5 7.0 1.8 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.6 RKO96504.1 - 0.24 11.2 2.7 0.62 9.9 2.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 RKO96504.1 - 0.27 11.1 1.1 0.55 10.1 1.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein OrfB_Zn_ribbon PF07282.11 RKO96504.1 - 0.36 10.8 3.6 2.7 8.0 1.4 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-MIZ PF02891.20 RKO96504.1 - 3.2 7.6 8.4 1.4 8.7 5.4 2.0 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Spt4 PF06093.13 RKO96504.1 - 7.9 6.7 10.8 0.29 11.3 2.9 2.6 3 0 0 3 3 3 0 Spt4/RpoE2 zinc finger UvdE PF03851.14 RKO96505.1 - 3.5e-77 259.3 0.0 4.2e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF1394 PF07159.12 RKO96506.1 - 6.1e-90 301.5 0.0 7.3e-90 301.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) ArfGap PF01412.18 RKO96507.1 - 1e-31 109.4 0.6 1.1e-31 109.3 0.6 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Abhydrolase_3 PF07859.13 RKO96508.1 - 3e-32 112.2 0.0 2.3e-23 83.2 0.0 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Pkinase PF00069.25 RKO96509.1 - 2.9e-49 167.8 0.0 3.5e-49 167.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96509.1 - 5.6e-20 71.7 0.0 7e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO96509.1 - 4.6e-05 22.9 0.0 7.5e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKO96509.1 - 0.0056 16.6 1.5 0.015 15.2 0.0 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 RKO96509.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_15 PF09445.10 RKO96510.1 - 1.9e-28 99.1 0.0 3.7e-28 98.2 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 RKO96510.1 - 8.7e-09 35.4 0.0 1.1e-08 35.1 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_25 PF13649.6 RKO96510.1 - 0.0032 18.1 0.3 0.0064 17.2 0.3 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RKO96510.1 - 0.0047 16.6 0.0 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical protein 95 DNA_methylase PF00145.17 RKO96510.1 - 0.19 11.1 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Oxysterol_BP PF01237.18 RKO96511.1 - 1.3e-75 254.6 0.0 1e-69 235.2 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein Cnd2 PF05786.14 RKO96512.1 - 0.12 11.0 4.0 0.13 10.9 4.0 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 HMG_box PF00505.19 RKO96512.1 - 0.13 12.7 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 HMG (high mobility group) box Hydantoinase_B PF02538.14 RKO96513.1 - 0.22 9.9 2.4 0.35 9.2 2.4 1.2 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase Spc7 PF08317.11 RKO96513.1 - 0.38 9.6 12.0 0.74 8.6 12.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein UPF0242 PF06785.11 RKO96513.1 - 0.57 10.3 10.6 0.27 11.3 7.8 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-H PF05837.12 RKO96513.1 - 2.6 8.5 13.6 5.7 7.4 5.9 2.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) BRE1 PF08647.11 RKO96513.1 - 6.8 6.8 9.4 30 4.8 0.2 2.6 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase APG6_N PF17675.1 RKO96513.1 - 7.9 7.0 22.7 35 4.9 11.3 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region FUSC_2 PF13515.6 RKO96514.1 - 1.5e-18 67.1 16.7 3e-18 66.2 16.7 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 RKO96514.1 - 8.2e-15 54.4 14.5 8.2e-15 54.4 14.5 1.9 2 1 1 3 3 3 1 Fusaric acid resistance protein family ALMT PF11744.8 RKO96514.1 - 1.5e-07 30.7 8.8 2.3e-07 30.1 8.8 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 RKO96514.1 - 0.00046 19.4 0.9 0.89 8.5 1.0 2.2 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal Na_H_Exchanger PF00999.21 RKO96515.1 - 1.5e-31 109.5 21.3 1.8e-31 109.3 21.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3180 PF11377.8 RKO96515.1 - 7.2 6.8 9.3 2.3 8.4 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Pkinase PF00069.25 RKO96516.1 - 3e-17 62.8 0.0 3.5e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96516.1 - 4.3e-07 29.5 0.0 7.3e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO96516.1 - 0.0068 15.2 0.0 0.012 14.4 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase DUF4096 PF13340.6 RKO96516.1 - 0.068 13.4 0.0 0.097 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) Katanin_con80 PF13925.6 RKO96517.1 - 0.037 14.1 1.3 0.079 13.0 0.2 2.1 2 0 0 2 2 2 0 con80 domain of Katanin CH PF00307.31 RKO96518.1 - 8.6e-11 42.0 0.0 1.3e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain FixH PF05751.11 RKO96518.1 - 0.03 14.3 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 FixH CAMSAP_CH PF11971.8 RKO96518.1 - 0.08 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Methyltransf_5 PF01795.19 RKO96519.1 - 1.6e-54 185.5 0.0 1.7e-28 100.0 0.0 2.6 2 1 0 2 2 2 2 MraW methylase family Methyltransf_25 PF13649.6 RKO96519.1 - 0.079 13.7 0.0 0.21 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain RGS PF00615.19 RKO96520.1 - 0.00057 20.1 0.3 0.0011 19.2 0.3 1.5 1 0 0 1 1 1 1 Regulator of G protein signaling domain ABC1 PF03109.16 RKO96522.1 - 2.2e-24 85.9 0.0 3.9e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 RKO96522.1 - 0.055 13.4 0.3 0.63 9.9 0.0 2.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 RKO96523.1 - 1.3e-13 51.1 4.2 0.00063 20.5 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO96523.1 - 5.7e-11 42.6 0.0 0.022 15.1 0.0 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 RKO96523.1 - 0.0099 14.4 0.0 0.23 9.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 RKO96523.1 - 0.057 12.3 0.1 0.096 11.6 0.1 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Ras PF00071.22 RKO96524.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Ras family TPR_14 PF13428.6 RKO96528.1 - 1.9e-09 37.5 18.4 0.0055 17.4 0.6 4.5 1 1 4 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 RKO96528.1 - 2.6e-08 33.4 10.3 0.11 12.6 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKO96528.1 - 3.9e-07 30.5 14.3 0.0074 16.8 0.3 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKO96528.1 - 2.6e-05 24.8 12.3 0.041 14.5 3.8 3.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 RKO96528.1 - 0.00014 21.8 4.0 2.3 8.7 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKO96528.1 - 0.00076 19.7 15.0 0.073 13.4 1.7 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO96528.1 - 0.0032 18.0 7.0 6.7 7.6 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO96528.1 - 0.016 15.3 13.8 0.025 14.7 3.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 RKO96528.1 - 0.084 13.3 0.2 2.2 8.7 0.1 2.5 1 1 2 3 3 3 0 Alkyl sulfatase dimerisation TPR_1 PF00515.28 RKO96528.1 - 0.32 10.9 8.4 1.7 8.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 RKO96528.1 - 4.9 8.1 16.4 8.1 7.4 1.5 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKO96528.1 - 6 6.9 10.0 11 6.0 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 RKO96528.1 - 7.8 6.9 11.2 46 4.4 1.1 3.0 1 1 1 2 2 2 0 Bacterial transcriptional activator domain Fungal_trans PF04082.18 RKO96529.1 - 8.1e-12 44.7 0.0 1.8e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SOG2 PF10428.9 RKO96529.1 - 0.026 13.7 9.4 0.045 12.9 9.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein PT-TG PF14449.6 RKO96529.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Pre-toxin TG Pep3_Vps18 PF05131.14 RKO96530.1 - 3.9e-26 91.7 0.2 7.9e-26 90.7 0.2 1.5 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 RKO96530.1 - 2.5e-06 27.4 0.1 4.4e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Region in Clathrin and VPS Vps39_2 PF10367.9 RKO96530.1 - 0.00039 20.8 0.0 0.0047 17.3 0.0 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.6 RKO96530.1 - 0.002 18.4 3.6 0.0045 17.3 3.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 RKO96530.1 - 0.0021 18.3 1.5 0.0048 17.1 1.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Cadherin_2 PF08266.12 RKO96530.1 - 0.04 13.7 0.3 0.15 11.9 0.1 2.0 3 0 0 3 3 3 0 Cadherin-like RPN1_RPN2_N PF17781.1 RKO96530.1 - 0.094 12.1 0.2 0.17 11.2 0.2 1.4 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain zf-RING_UBOX PF13445.6 RKO96530.1 - 0.13 12.3 5.5 0.25 11.4 5.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 RKO96530.1 - 0.14 12.2 3.5 0.21 11.7 2.2 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sigma70_r1_1 PF03979.14 RKO96530.1 - 0.2 11.7 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 zf-RING_11 PF17123.5 RKO96530.1 - 0.2 11.4 6.2 0.42 10.4 6.2 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 RKO96530.1 - 0.88 9.5 4.0 1.8 8.5 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TIP39 PF14980.6 RKO96530.1 - 1.7 8.6 4.3 16 5.5 0.1 2.6 2 0 0 2 2 2 0 TIP39 peptide zf-P11 PF03854.14 RKO96530.1 - 9.7 5.9 7.2 0.64 9.7 1.1 2.2 3 0 0 3 3 3 0 P-11 zinc finger DUF4448 PF14610.6 RKO96531.1 - 0.0055 16.5 0.3 0.0084 15.9 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 RKO96531.1 - 0.022 15.6 0.0 0.057 14.3 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.6 RKO96531.1 - 0.054 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Stevor PF17410.2 RKO96531.1 - 0.086 12.4 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SCF PF02404.15 RKO96531.1 - 0.26 10.6 0.5 0.64 9.3 0.5 1.6 1 0 0 1 1 1 0 Stem cell factor Apt1 PF10351.9 RKO96531.1 - 0.35 9.7 4.5 0.42 9.4 4.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF202 PF02656.15 RKO96531.1 - 5.6 7.5 6.1 0.33 11.4 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF202) SPX PF03105.19 RKO96531.1 - 7.4 6.4 16.3 11 5.9 16.3 1.3 1 0 0 1 1 1 0 SPX domain PT PF04886.12 RKO96532.1 - 0.0061 16.1 1.6 0.014 14.9 1.6 1.6 1 0 0 1 1 1 1 PT repeat Med10 PF09748.9 RKO96533.1 - 5.7e-28 97.3 0.0 6.3e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex HTH_31 PF13560.6 RKO96533.1 - 0.027 14.8 0.1 0.052 13.9 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain MFS_1 PF07690.16 RKO96534.1 - 4.3e-09 35.8 8.6 8.6e-09 34.8 8.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 RKO96534.1 - 3.7e-08 32.7 2.2 4.7e-08 32.3 2.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Ank_2 PF12796.7 RKO96540.1 - 7.4e-26 90.6 3.3 5.8e-15 55.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 RKO96540.1 - 2e-23 82.5 2.8 1.5e-11 44.6 0.4 3.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 RKO96540.1 - 3e-21 75.2 5.7 3e-10 40.1 1.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 RKO96540.1 - 2.3e-18 65.7 6.8 9.8e-07 29.0 0.2 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 RKO96540.1 - 2.6e-16 58.0 2.6 9e-06 25.7 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat NDT80_PhoG PF05224.12 RKO96542.1 - 3.6e-29 102.3 0.0 1.4e-28 100.4 0.0 1.9 1 1 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Zip PF02535.22 RKO96542.1 - 8.1 5.5 5.5 14 4.8 5.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter GTP_EFTU PF00009.27 RKO96543.1 - 3.8e-58 196.3 0.3 5.3e-58 195.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RKO96543.1 - 8.4e-28 96.9 0.0 1.7e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RKO96543.1 - 1.1e-19 70.6 4.0 3.1e-19 69.1 4.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RKO96543.1 - 2.9e-05 24.1 0.0 6.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 RKO96543.1 - 0.00097 18.8 1.1 0.0014 18.3 0.1 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 RKO96543.1 - 0.013 15.5 0.1 0.028 14.3 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 RKO96543.1 - 0.036 13.8 0.1 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation tRNA-synt_2 PF00152.20 RKO96544.1 - 4.4e-89 298.7 0.0 5.1e-89 298.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RKO96544.1 - 4.3e-10 39.5 0.0 7.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 RKO96544.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain TB2_DP1_HVA22 PF03134.19 RKO96545.1 - 2.1e-23 82.0 4.7 2.7e-23 81.7 4.7 1.1 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bap31 PF05529.12 RKO96545.1 - 0.16 11.9 1.3 0.2 11.5 1.3 1.1 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region Aminotran_1_2 PF00155.21 RKO96546.1 - 2.5e-58 198.0 0.0 2.8e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 RKO96546.1 - 5.5e-08 32.5 0.0 7.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 RKO96546.1 - 0.00015 20.8 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RKO96546.1 - 0.0035 15.9 0.0 0.0053 15.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 RKO96546.1 - 0.037 13.3 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase WD40 PF00400.32 RKO96548.1 - 1.1e-12 48.2 3.1 7.1e-05 23.5 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.7 RKO96548.1 - 8.1e-07 28.8 0.0 2.3e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 RKO96548.1 - 0.0081 16.0 0.2 0.087 12.7 0.1 2.1 2 0 0 2 2 2 1 F-box domain RhoGAP PF00620.27 RKO96549.1 - 1.6e-40 138.4 0.0 3.5e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 RKO96549.1 - 5.9e-10 39.3 0.0 3.4e-09 36.8 0.0 2.4 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4085 PF13315.6 RKO96549.1 - 0.059 13.0 0.5 0.093 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) DUF1708 PF08101.11 RKO96549.1 - 0.1 11.7 0.0 0.44 9.6 0.0 1.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1708) gag-asp_proteas PF13975.6 RKO96550.1 - 1.1e-05 25.9 0.0 2.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC PF00098.23 RKO96550.1 - 6e-05 22.9 2.0 6e-05 22.9 2.0 2.2 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 RKO96550.1 - 0.0034 18.0 0.1 0.0071 17.0 0.1 1.6 1 0 0 1 1 1 1 Aspartyl protease Asp_protease PF09668.10 RKO96550.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 RKO96550.1 - 0.022 15.0 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein Yippee-Mis18 PF03226.14 RKO96551.1 - 1.6e-13 50.8 1.9 1.9e-13 50.5 1.9 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 RKO96551.1 - 0.023 14.9 0.8 0.036 14.3 0.8 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I ADIP PF11559.8 RKO96552.1 - 0.0021 18.1 0.9 0.0021 18.1 0.9 1.7 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 RKO96552.1 - 0.066 13.2 5.4 0.12 12.4 5.4 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 RKO96552.1 - 0.12 12.8 4.1 0.17 12.3 4.1 1.2 1 0 0 1 1 1 0 Fez1 DUF3685 PF12452.8 RKO96552.1 - 0.23 11.1 0.4 0.35 10.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) YabA PF06156.13 RKO96552.1 - 0.42 11.3 2.3 0.32 11.7 0.6 1.6 2 0 0 2 2 2 0 Initiation control protein YabA T3SS_TC PF06511.11 RKO96552.1 - 0.44 9.9 1.6 0.71 9.2 1.6 1.3 1 0 0 1 1 1 0 Type III secretion systems tip complex components APG6_N PF17675.1 RKO96552.1 - 1.8 9.1 9.3 0.58 10.7 3.7 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region UPF0203 PF05254.12 RKO96554.1 - 1.5e-24 86.0 1.6 1.7e-24 85.9 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 RKO96554.1 - 0.024 14.8 1.0 0.22 11.8 0.9 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX17 PF05051.13 RKO96554.1 - 0.066 13.6 0.7 0.25 11.7 0.7 1.8 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) DUF5339 PF17274.2 RKO96554.1 - 0.18 12.7 0.7 43 5.1 0.1 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5339) UQ_con PF00179.26 RKO96555.1 - 1.2e-15 57.4 0.0 1.2e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RKO96555.1 - 0.00014 21.7 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 RKO96555.1 - 0.022 15.0 0.0 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain FERM_M PF00373.18 RKO96558.1 - 5.5e-12 46.1 0.0 8.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 FERM central domain RasGEF_N PF00618.20 RKO96559.1 - 6.5e-21 74.5 0.0 1.5e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DEAD PF00270.29 RKO96560.1 - 8.4e-49 165.7 0.0 3.8e-48 163.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO96560.1 - 4.7e-32 110.6 0.0 1.7e-31 108.9 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO96560.1 - 0.0035 17.4 0.0 0.012 15.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 RKO96560.1 - 0.023 13.5 0.0 0.36 9.5 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Ras PF00071.22 RKO96561.1 - 7e-37 126.5 0.0 7.8e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO96561.1 - 2.2e-29 102.1 0.0 2.5e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO96561.1 - 5.3e-11 42.3 0.0 6.4e-11 42.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 RKO96561.1 - 4.8e-05 23.4 0.0 5.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RKO96561.1 - 0.0015 17.9 0.0 0.0016 17.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 RKO96561.1 - 0.0019 18.6 0.0 0.0019 18.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain UPF0139 PF03669.13 RKO96562.1 - 5.6e-11 42.2 0.1 7.1e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Chorismate_synt PF01264.21 RKO96563.1 - 6.5e-128 426.0 0.0 7.5e-128 425.8 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase RRM_1 PF00076.22 RKO96564.1 - 1e-21 76.5 0.0 1.2e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L21e PF01157.18 RKO96565.1 - 2.2e-46 155.9 4.5 3.3e-46 155.3 4.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L21e DUF1996 PF09362.10 RKO96568.1 - 1.7e-56 191.9 0.4 2.1e-56 191.6 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SCAI PF12070.8 RKO96569.1 - 3.5e-169 564.1 0.0 4.3e-169 563.8 0.0 1.0 1 0 0 1 1 1 1 Protein SCAI Aldedh PF00171.22 RKO96570.1 - 2.9e-81 273.3 4.4 3.3e-81 273.2 4.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF2605 PF10792.9 RKO96570.1 - 0.12 12.3 0.1 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) LPMO_10 PF03067.15 RKO96572.1 - 7.7e-07 30.0 0.1 5.9e-06 27.1 0.1 2.2 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading WD40 PF00400.32 RKO96574.1 - 4e-17 62.3 23.4 0.00066 20.4 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO96574.1 - 3.3e-15 56.1 2.2 0.00031 21.0 0.1 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO96574.1 - 5.1e-05 22.4 1.5 0.019 13.9 0.5 3.8 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 RKO96574.1 - 0.0031 17.4 0.1 0.15 11.9 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A FlgN PF05130.12 RKO96575.1 - 0.032 14.7 5.6 0.041 14.4 0.1 2.9 2 1 0 2 2 2 0 FlgN protein Hap4_Hap_bind PF10297.9 RKO96575.1 - 0.6 10.3 9.4 0.25 11.5 6.1 2.2 1 1 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 cNMP_binding PF00027.29 RKO96576.1 - 5.5e-12 45.6 0.0 2.5e-05 24.3 0.0 3.8 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain zf-Tim10_DDP PF02953.15 RKO96577.1 - 3.2e-20 71.5 0.9 3.7e-20 71.3 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Myb_DNA-bind_5 PF13873.6 RKO96577.1 - 0.055 13.6 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3331 PF11811.8 RKO96578.1 - 0.059 13.2 1.3 0.069 13.0 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3331) HAUS4 PF14735.6 RKO96579.1 - 4.4e-06 26.6 0.1 6.8e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 AbiJ_NTD5 PF18865.1 RKO96579.1 - 0.048 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 Baculo_PEP_C PF04513.12 RKO96579.1 - 0.18 11.8 0.0 8.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TPR_MLP1_2 PF07926.12 RKO96579.1 - 0.24 11.4 1.8 3 7.9 0.6 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Med3 PF11593.8 RKO96579.1 - 1.3 8.1 5.6 2.3 7.3 5.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L14 PF00238.19 RKO96580.1 - 6.9e-36 123.0 0.0 8.2e-36 122.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 RKO96580.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal DUF1180 PF06679.12 RKO96581.1 - 0.1 13.0 4.9 0.13 12.6 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) VEGFR-2_TMD PF17988.1 RKO96581.1 - 0.28 10.7 3.1 0.57 9.7 3.1 1.5 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain DUF2207 PF09972.9 RKO96583.1 - 0.055 12.2 0.5 0.12 11.1 0.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.6 RKO96583.1 - 0.12 12.1 5.5 0.25 11.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cas1_AcylT PF07779.12 RKO96584.1 - 4e-103 345.9 13.2 5.3e-103 345.5 13.2 1.1 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p EF-hand_1 PF00036.32 RKO96585.1 - 4.8e-26 88.3 3.0 9.1e-06 24.9 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RKO96585.1 - 3.1e-23 82.0 1.4 7.5e-12 45.5 0.3 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 RKO96585.1 - 1.2e-20 71.5 2.1 7.1e-05 22.4 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RKO96585.1 - 4.3e-19 67.1 2.7 5.4e-06 25.7 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RKO96585.1 - 8.4e-15 54.4 6.4 0.009 15.8 0.0 4.5 3 2 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 RKO96585.1 - 9.8e-08 32.3 0.0 0.0023 18.2 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Anthrax-tox_M PF09156.10 RKO96585.1 - 0.00034 20.1 0.1 0.055 12.8 0.0 2.1 2 0 0 2 2 2 2 Anthrax toxin lethal factor, middle domain EF-hand_9 PF14658.6 RKO96585.1 - 0.0032 17.8 0.1 0.42 11.0 0.0 2.5 2 1 1 3 3 3 1 EF-hand domain Sigma54_CBD PF04963.13 RKO96585.1 - 0.0064 16.4 0.1 0.12 12.3 0.0 2.2 1 1 0 2 2 2 1 Sigma-54 factor, core binding domain GTP_EFTU PF00009.27 RKO96586.1 - 5.1e-40 137.1 0.0 6.6e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 RKO96586.1 - 1e-33 116.0 1.4 3.8e-33 114.1 0.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 RKO96586.1 - 3e-07 30.7 0.2 6.9e-07 29.6 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 RKO96586.1 - 0.0024 17.9 0.2 0.038 14.1 0.1 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 RKO96586.1 - 0.056 13.4 0.8 0.15 12.0 0.2 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 Tim17 PF02466.19 RKO96587.1 - 6.2e-32 110.3 8.2 7.5e-32 110.0 8.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.6 RKO96587.1 - 0.18 11.9 4.2 2.5 8.2 0.2 2.4 2 0 0 2 2 2 0 Glycine zipper MFS_1 PF07690.16 RKO96588.1 - 5.6e-28 97.9 21.4 6e-28 97.8 21.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily PTR2 PF00854.21 RKO96588.1 - 0.014 14.2 3.6 0.017 14.0 3.6 1.3 1 1 0 1 1 1 0 POT family PXA PF02194.15 RKO96589.1 - 2.1e-28 99.5 0.0 5.8e-28 98.1 0.0 1.7 2 0 0 2 2 2 1 PXA domain Cyt-b5 PF00173.28 RKO96590.1 - 2.3e-20 72.5 0.0 2.6e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain eIF3_N PF09440.10 RKO96592.1 - 4.2e-34 117.9 5.0 9.2e-34 116.8 5.0 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 RKO96592.1 - 9e-12 45.4 0.4 3.2e-11 43.7 0.0 2.1 2 1 0 2 2 2 1 PCI domain Kinesin PF00225.23 RKO96594.1 - 3.6e-117 391.0 0.0 4.1e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO96594.1 - 2.1e-29 102.4 0.0 4.9e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Ribosomal_L2_C PF03947.18 RKO96595.1 - 2.4e-48 163.5 2.9 3.5e-48 163.0 2.9 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RKO96595.1 - 8e-15 54.6 0.0 2.2e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain TT_ORF2a PF08197.11 RKO96595.1 - 0.014 15.3 0.9 0.037 14.0 0.9 1.7 1 0 0 1 1 1 0 pORF2a truncated protein zf-CCHC PF00098.23 RKO96596.1 - 0.0056 16.7 14.7 0.02 14.9 0.3 3.7 3 1 0 3 3 3 2 Zinc knuckle zf-CCHC_3 PF13917.6 RKO96596.1 - 0.011 15.7 14.6 0.21 11.6 0.1 3.5 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 RKO96596.1 - 0.049 13.4 0.5 0.049 13.4 0.5 4.1 5 0 0 5 5 5 0 Zinc knuckle SGP PF17228.2 RKO96596.1 - 2.9 8.8 9.5 7 7.6 9.4 1.7 1 1 0 1 1 1 0 Sulphur globule protein eIF3g PF12353.8 RKO96596.1 - 8.8 6.7 28.6 0.18 12.2 0.9 4.7 3 1 2 5 5 5 0 Eukaryotic translation initiation factor 3 subunit G TMEM208_SND2 PF05620.11 RKO96597.1 - 6.9e-17 61.7 0.0 7.5e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 ASF1_hist_chap PF04729.13 RKO96598.1 - 1.3e-55 187.6 0.0 1.5e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone CKS PF01111.19 RKO96599.1 - 3.2e-33 113.8 0.2 4e-33 113.5 0.2 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit INSC_LBD PF16748.5 RKO96599.1 - 0.0045 16.4 0.1 0.0072 15.8 0.1 1.3 1 0 0 1 1 1 1 Inscuteable LGN-binding domain SpoU_methylase PF00588.19 RKO96600.1 - 9.6e-14 51.8 0.0 1.2e-07 32.0 0.0 3.8 2 2 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 RKO96600.1 - 0.00015 22.0 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 RNA 2'-O ribose methyltransferase substrate binding Inhibitor_I9 PF05922.16 RKO96601.1 - 2.9e-07 31.0 0.0 6e-07 30.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase inhibitor I9 DAHP_snth_FXD PF18152.1 RKO96601.1 - 0.094 12.6 0.1 0.21 11.4 0.1 1.6 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Pkinase PF00069.25 RKO96602.1 - 1.6e-35 122.7 0.9 1.9e-35 122.5 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96602.1 - 1.3e-18 67.3 0.3 1.5e-18 67.0 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RPA_C PF08784.11 RKO96603.1 - 1.5e-08 35.2 1.1 1.5e-08 35.2 1.1 2.1 2 1 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 RKO96603.1 - 2.8e-07 30.4 0.1 1.2e-06 28.4 0.1 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 RKO96603.1 - 0.027 14.3 0.1 0.25 11.2 0.1 2.3 1 1 0 1 1 1 0 RecQ-mediated genome instability protein 2 tRNA_anti_2 PF13742.6 RKO96603.1 - 0.04 14.1 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain Cation_ATPase_C PF00689.21 RKO96605.1 - 2.6e-45 154.3 5.6 3.7e-45 153.9 5.6 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 RKO96605.1 - 2.8e-07 31.0 0.0 5.7e-07 30.0 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 RKO96605.1 - 8.3e-06 25.7 0.7 1.4e-05 25.0 0.7 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4514 PF14986.6 RKO96605.1 - 1.1 9.3 3.1 0.66 10.0 0.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4514) Cation_ATPase_N PF00690.26 RKO96606.1 - 1.4e-20 72.7 0.3 2.9e-19 68.5 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus E1-E2_ATPase PF00122.20 RKO96606.1 - 3.8e-18 65.6 0.8 5.4e-17 61.9 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase PfkB PF00294.24 RKO96611.1 - 8.9e-29 100.7 0.0 1e-28 100.5 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Cytochrom_C1 PF02167.15 RKO96613.1 - 3.8e-93 311.2 0.0 4.4e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 RKO96613.1 - 0.0025 18.1 0.1 0.0056 17.0 0.1 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 RKO96613.1 - 0.015 16.4 0.3 0.036 15.2 0.3 1.7 1 1 0 1 1 1 0 Cytochrome c HTH_27 PF13463.6 RKO96614.1 - 0.13 12.7 0.0 0.4 11.2 0.0 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain Sgf11 PF08209.11 RKO96615.1 - 2.5e-08 33.3 2.0 7.2e-08 31.9 2.0 1.8 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) Spt20 PF12090.8 RKO96616.1 - 0.77 9.3 9.9 1 8.9 9.9 1.1 1 0 0 1 1 1 0 Spt20 family DEAD PF00270.29 RKO96617.1 - 2.7e-43 147.8 0.0 4.4e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO96617.1 - 9.7e-29 100.0 0.0 2.6e-28 98.6 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO96617.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Hydrolase_4 PF12146.8 RKO96618.1 - 5.4e-57 192.8 0.3 6.1e-57 192.6 0.3 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RKO96618.1 - 7.5e-21 74.9 0.3 7.5e-16 58.5 0.3 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 RKO96618.1 - 2.5e-12 47.9 5.2 3.2e-12 47.6 5.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 RKO96618.1 - 1.1e-05 25.0 0.1 0.077 12.5 0.1 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Esterase PF00756.20 RKO96618.1 - 2.1e-05 24.3 0.1 3.1e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Putative esterase AXE1 PF05448.12 RKO96618.1 - 0.00038 19.2 0.9 0.042 12.5 0.9 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 RKO96618.1 - 0.0038 17.4 0.2 0.0051 16.9 0.2 1.3 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.18 RKO96618.1 - 0.019 14.6 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 RKO96618.1 - 0.025 14.4 0.1 2.6 7.8 0.0 2.8 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Peptidase_S28 PF05577.12 RKO96618.1 - 0.037 12.8 0.0 0.051 12.4 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 DLH PF01738.18 RKO96618.1 - 0.16 11.5 0.0 1.6 8.3 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.9 RKO96618.1 - 0.28 10.6 3.7 1.1 8.7 1.7 2.1 1 1 0 2 2 2 0 Esterase PHB depolymerase Arf PF00025.21 RKO96622.1 - 1.5e-66 223.2 0.0 1.6e-66 223.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 RKO96622.1 - 1e-10 41.3 0.0 2.4e-07 30.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RKO96622.1 - 2.9e-07 30.1 0.0 3.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 RKO96622.1 - 3.4e-07 30.5 0.0 8.1e-07 29.3 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 RKO96622.1 - 5.1e-07 29.8 0.0 1e-06 28.8 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 RKO96622.1 - 3.6e-06 26.7 0.0 4.4e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 RKO96622.1 - 1.8e-05 24.2 0.0 2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 RKO96622.1 - 0.043 13.6 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PT PF04886.12 RKO96623.1 - 1 9.0 10.0 3 7.4 10.0 1.8 1 0 0 1 1 1 0 PT repeat DUF4874 PF16173.5 RKO96625.1 - 3.3e-11 43.1 0.0 4.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) PPP4R2 PF09184.11 RKO96625.1 - 0.0044 16.7 2.6 0.0054 16.4 2.6 1.2 1 0 0 1 1 1 1 PPP4R2 DUF4832 PF16116.5 RKO96625.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) SGT1 PF07093.11 RKO96625.1 - 5.1 5.4 9.9 6.9 5.0 9.9 1.1 1 0 0 1 1 1 0 SGT1 protein SRP54 PF00448.22 RKO96626.1 - 6.2e-33 114.1 0.1 8.5e-20 71.2 0.0 2.8 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 RKO96626.1 - 3.1e-24 85.5 1.6 3.1e-24 85.5 1.6 2.7 2 0 0 2 2 2 1 Signal peptide binding domain EcsC PF12787.7 RKO96626.1 - 0.0038 16.9 0.0 0.0058 16.3 0.0 1.4 1 1 0 1 1 1 1 EcsC protein family DUF2587 PF10759.9 RKO96626.1 - 0.23 11.0 5.0 0.68 9.4 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) TTL PF03133.15 RKO96627.1 - 3.7e-71 239.7 0.0 4.2e-71 239.5 0.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 RKO96627.1 - 1.2e-08 34.5 0.0 4.4e-05 22.9 0.0 3.2 2 2 1 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 RKO96627.1 - 7.3e-06 25.4 0.0 0.0026 17.0 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 RKO96627.1 - 0.0031 17.6 0.0 0.29 11.2 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp domain UBX PF00789.20 RKO96628.1 - 0.034 14.4 0.0 0.053 13.7 0.0 1.3 1 0 0 1 1 1 0 UBX domain LRR_8 PF13855.6 RKO96630.1 - 0.014 15.2 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Leucine rich repeat SRA1 PF07304.11 RKO96631.1 - 0.00044 20.1 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 RKO96631.1 - 0.094 12.8 0.0 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Prp18 domain SUIM_assoc PF16619.5 RKO96631.1 - 2.5 8.2 8.1 6.4 6.9 8.1 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Fis1_TPR_C PF14853.6 RKO96632.1 - 6.9e-23 80.5 1.5 1e-22 79.9 1.5 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 RKO96632.1 - 3.1e-15 55.5 0.0 4.9e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 RKO96632.1 - 0.00028 21.3 0.1 0.00046 20.6 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKO96632.1 - 0.0055 16.7 1.5 0.0055 16.7 1.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKO96632.1 - 0.037 14.7 2.4 0.11 13.2 0.4 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO96632.1 - 0.05 13.8 0.1 0.083 13.1 0.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 RKO96632.1 - 0.093 13.0 1.8 0.22 11.8 1.6 1.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKO96632.1 - 0.11 12.6 1.8 0.15 12.2 0.8 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKO96632.1 - 0.24 11.3 2.6 0.37 10.7 1.7 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 RKO96632.1 - 0.5 10.3 3.4 0.53 10.2 1.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Complex1_49kDa PF00346.19 RKO96634.1 - 8.4e-122 405.5 0.0 1.1e-121 405.1 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 RKO96634.1 - 0.016 14.1 0.0 0.071 12.0 0.0 1.9 1 1 1 2 2 2 0 Nickel-dependent hydrogenase Sel1 PF08238.12 RKO96635.1 - 3.1e-23 81.7 41.4 1.1e-05 26.0 0.3 12.6 12 0 0 12 12 12 8 Sel1 repeat TPR_2 PF07719.17 RKO96635.1 - 0.094 12.9 0.4 0.094 12.9 0.4 6.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKO96635.1 - 0.3 11.4 5.8 2 8.8 0.6 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat COX17 PF05051.13 RKO96637.1 - 5e-20 71.6 9.4 5.6e-20 71.4 9.4 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) NAM-associated PF14303.6 RKO96638.1 - 0.084 13.6 1.8 0.13 13.0 1.8 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Sof1 PF04158.14 RKO96639.1 - 5.6e-22 77.8 9.8 1.1e-21 76.9 9.8 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 RKO96639.1 - 2e-18 66.4 8.8 0.0004 21.1 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO96639.1 - 1.1e-05 25.6 0.3 0.075 13.3 0.0 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 RKO96639.1 - 2.6e-05 24.2 0.1 0.26 11.2 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Axin_b-cat_bind PF08833.10 RKO96639.1 - 0.032 14.3 0.3 0.19 11.9 0.0 2.4 3 0 0 3 3 3 0 Axin beta-catenin binding domain Cpn60_TCP1 PF00118.24 RKO96642.1 - 4.3e-146 487.4 11.8 4.9e-146 487.2 11.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TetR_C_14 PF17754.1 RKO96642.1 - 0.13 12.2 9.9 0.029 14.3 6.0 2.0 2 0 0 2 2 2 0 MftR C-terminal domain RRM_1 PF00076.22 RKO96643.1 - 2.3e-10 40.2 0.0 0.015 15.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 RKO96643.1 - 0.01 15.8 0.0 3.4 7.7 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif LSM PF01423.22 RKO96644.1 - 8.7e-18 63.8 0.1 1.1e-17 63.5 0.1 1.1 1 0 0 1 1 1 1 LSM domain SelK_SelG PF10961.8 RKO96644.1 - 0.47 11.1 3.2 0.74 10.5 2.5 1.8 1 1 0 1 1 1 0 Selenoprotein SelK_SelG RRN3 PF05327.11 RKO96645.1 - 2.8e-79 267.1 0.8 3.6e-79 266.8 0.8 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 TFIIE-A_C PF11521.8 RKO96645.1 - 2.1 8.7 13.4 0.48 10.7 2.6 2.3 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Aldedh PF00171.22 RKO96646.1 - 9.7e-42 143.0 0.1 1.1e-41 142.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DNApol_Exo PF18136.1 RKO96647.1 - 5.9e-53 179.8 0.0 1e-52 179.1 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 RKO96647.1 - 1.4e-41 142.9 0.0 2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A DUF3678 PF12435.8 RKO96647.1 - 2.7 7.5 6.7 2.2 7.8 4.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) THUMP PF02926.17 RKO96648.1 - 3.5e-13 49.9 0.0 4.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 THUMP domain Lir1 PF07207.11 RKO96648.1 - 0.12 12.6 2.2 0.15 12.3 0.6 2.1 2 1 0 2 2 2 0 Light regulated protein Lir1 Ion_trans PF00520.31 RKO96649.1 - 1.6e-05 24.3 0.2 1.9e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 RKO96649.1 - 0.015 15.2 2.9 0.039 13.9 2.9 1.6 1 1 0 1 1 1 0 Ion channel Paf67 PF10255.9 RKO96650.1 - 3.5e-22 79.0 0.0 4.7e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PAS PF00989.25 RKO96650.1 - 0.0087 16.0 0.0 0.029 14.4 0.0 1.8 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 RKO96650.1 - 0.021 15.1 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 RKO96650.1 - 0.056 13.7 0.9 0.69 10.2 0.0 3.0 2 1 1 3 3 3 0 PAS fold CbiD PF01888.17 RKO96650.1 - 0.37 10.0 2.3 1 8.6 2.3 1.7 1 0 0 1 1 1 0 CbiD Mito_carr PF00153.27 RKO96651.1 - 2.8e-71 235.5 0.1 2.7e-25 88.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 RKO96651.1 - 5e-17 60.1 0.9 0.00028 20.2 0.0 5.4 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 RKO96651.1 - 1.2e-16 60.9 0.7 0.00035 20.9 0.0 4.2 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RKO96651.1 - 2.4e-14 52.0 2.1 0.0027 17.5 0.2 6.0 7 0 0 7 7 7 3 EF-hand domain EF-hand_8 PF13833.6 RKO96651.1 - 4e-13 49.0 2.9 0.0096 15.7 0.0 5.8 5 1 0 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.6 RKO96651.1 - 0.00026 20.3 0.2 0.9 9.1 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 RKO96651.1 - 0.0035 17.6 0.2 13 6.1 0.0 4.0 3 1 0 3 3 3 1 EF-hand domain Dynein_attach_N PF15867.5 RKO96651.1 - 0.2 11.6 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 Dynein attachment factor N-terminus Abhydrolase_1 PF00561.20 RKO96652.1 - 6.8e-05 22.6 0.1 0.00014 21.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 RKO96652.1 - 0.0085 16.0 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 RKO96652.1 - 0.0088 15.3 1.5 0.21 10.8 1.2 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 PRIMA1 PF16101.5 RKO96653.1 - 0.0043 17.1 8.4 0.017 15.2 8.4 2.0 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 MutS_V PF00488.21 RKO96654.1 - 2.4e-72 242.9 0.0 5.8e-72 241.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RKO96654.1 - 4.5e-31 108.6 0.4 7.7e-31 107.8 0.4 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 RKO96654.1 - 4.9e-30 104.1 0.0 1.2e-29 102.8 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 RKO96654.1 - 1e-10 42.0 0.0 2.6e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 RKO96654.1 - 4e-09 36.7 0.0 9.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV Cyclin_N PF00134.23 RKO96655.1 - 1.1e-10 41.3 0.0 1.3e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 RKO96655.1 - 1.3e-05 25.6 0.0 1.5e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin AAA PF00004.29 RKO96656.1 - 7.7e-43 146.1 0.0 1.3e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RKO96656.1 - 1.3e-10 41.0 0.1 2.9e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RKO96656.1 - 2.2e-09 37.0 0.7 3.9e-09 36.2 0.7 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RKO96656.1 - 7.4e-07 29.4 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 RKO96656.1 - 6.3e-06 26.5 0.1 0.002 18.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RKO96656.1 - 3.7e-05 23.0 0.0 6.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 RKO96656.1 - 4.2e-05 23.6 0.1 0.00031 20.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO96656.1 - 5.5e-05 23.6 0.1 0.0018 18.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 RKO96656.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 RKO96656.1 - 0.0013 19.3 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 RKO96656.1 - 0.002 18.4 0.1 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RKO96656.1 - 0.0028 17.4 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 RKO96656.1 - 0.0054 16.9 0.0 0.0096 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RKO96656.1 - 0.0065 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RKO96656.1 - 0.0069 16.8 0.0 0.021 15.2 0.0 1.8 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.13 RKO96656.1 - 0.0085 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 RKO96656.1 - 0.017 14.5 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 RKO96656.1 - 0.026 13.8 0.1 0.47 9.8 0.0 2.2 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.11 RKO96656.1 - 0.03 14.2 0.0 0.076 12.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 RKO96656.1 - 0.03 13.8 0.1 0.091 12.2 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 RKO96656.1 - 0.036 13.8 0.8 0.078 12.7 0.2 2.0 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RKO96656.1 - 0.043 13.3 0.1 0.12 11.8 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 RKO96656.1 - 0.053 13.1 0.6 0.4 10.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 RKO96656.1 - 0.067 12.9 0.2 0.22 11.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RKO96656.1 - 0.082 12.8 0.0 0.6 10.0 0.0 2.2 1 1 1 2 2 2 0 NACHT domain TsaE PF02367.17 RKO96656.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Prot_ATP_OB_N PF17758.1 RKO96656.1 - 0.12 12.1 0.0 0.38 10.4 0.0 1.9 1 0 0 1 1 1 0 Proteasomal ATPase OB N-terminal domain NB-ARC PF00931.22 RKO96656.1 - 0.14 11.4 0.0 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain Parvo_NS1 PF01057.17 RKO96656.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 RKO96656.1 - 0.14 12.6 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.26 RKO96656.1 - 0.16 11.7 0.0 0.6 9.8 0.0 1.9 3 0 0 3 3 2 0 Sigma-54 interaction domain ATPase_2 PF01637.18 RKO96656.1 - 0.8 9.6 3.5 1.8 8.4 0.0 2.8 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea HEAT PF02985.22 RKO96657.1 - 1.7e-29 99.3 29.6 0.0043 17.2 0.1 11.5 12 0 0 12 12 12 8 HEAT repeat HEAT_2 PF13646.6 RKO96657.1 - 1.4e-24 86.3 23.7 4e-08 33.5 0.0 6.5 1 1 7 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 RKO96657.1 - 5.5e-09 36.5 0.3 0.0035 17.9 0.2 5.7 2 2 4 6 6 6 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 RKO96657.1 - 3.5e-08 33.6 6.6 0.075 13.1 0.1 4.1 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RKO96657.1 - 5.3e-06 26.8 30.8 0.0024 18.3 0.1 7.7 8 3 2 10 10 10 3 HEAT-like repeat RTP1_C1 PF10363.9 RKO96657.1 - 7.4e-05 22.9 2.1 4.2 7.6 0.1 3.8 3 1 1 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 RKO96657.1 - 0.00013 20.7 9.6 0.16 10.5 0.2 4.0 3 1 0 3 3 3 2 Adaptin N terminal region DRIM PF07539.12 RKO96657.1 - 0.27 9.5 3.2 1.1 7.5 0.1 2.3 1 1 0 2 2 2 0 Down-regulated in metastasis Arm PF00514.23 RKO96657.1 - 0.31 11.2 16.6 3.7 7.7 0.0 6.5 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat Ecm29 PF13001.7 RKO96657.1 - 0.34 9.5 1.7 4.1 6.0 0.1 2.5 2 0 0 2 2 2 0 Proteasome stabiliser Cohesin_HEAT PF12765.7 RKO96657.1 - 3.4 8.1 7.2 8.3 6.8 0.1 3.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion RNA_pol_3_Rpc31 PF11705.8 RKO96658.1 - 6.7e-18 65.8 0.5 1.1e-17 65.0 0.5 1.3 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 RKO96658.1 - 8.3 5.9 6.7 6.6 6.2 5.5 1.4 2 0 0 2 2 2 0 PPP4R2 Ribosomal_L27A PF00828.19 RKO96659.1 - 0.00058 20.5 0.3 0.00058 20.5 0.3 1.4 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 RKO96659.1 - 0.13 12.3 0.7 0.16 12.1 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) UPF0113_N PF17833.1 RKO96660.1 - 4.1e-27 94.6 0.0 4.5e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain K_channel_TID PF07941.11 RKO96661.1 - 0.36 11.3 11.6 0.49 10.9 9.8 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Sec66 PF09802.9 RKO96662.1 - 6.4e-27 94.3 0.0 7e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF4681 PF15732.5 RKO96662.1 - 0.15 12.3 0.3 0.26 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4681) Apo-CIII PF05778.12 RKO96663.1 - 0.48 10.1 4.0 0.92 9.2 0.1 2.5 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) DUF1664 PF07889.12 RKO96663.1 - 0.5 10.4 12.2 0.81 9.7 0.8 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) JIP_LZII PF16471.5 RKO96663.1 - 1.6 9.0 21.7 0.35 11.1 0.6 5.0 5 2 1 6 6 6 0 JNK-interacting protein leucine zipper II Prominin PF05478.11 RKO96663.1 - 1.7 6.5 10.3 0.87 7.5 7.8 1.6 1 1 1 2 2 2 0 Prominin Baculo_PEP_C PF04513.12 RKO96663.1 - 3.2 7.8 7.1 3.9 7.5 0.3 3.2 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 RKO96663.1 - 3.4 8.0 20.2 20 5.5 13.7 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) Lectin_N PF03954.14 RKO96663.1 - 7.3 6.4 12.0 2.9 7.6 1.6 3.2 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain DUF573 PF04504.14 RKO96663.1 - 8.2 7.2 12.2 0.94 10.2 0.9 3.6 2 1 0 2 2 2 0 Protein of unknown function, DUF573 SH3_1 PF00018.28 RKO96666.1 - 2.4e-15 55.9 0.0 2.6e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKO96666.1 - 5.3e-10 39.0 0.2 6.3e-10 38.8 0.2 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKO96666.1 - 9.6e-06 25.2 0.0 9.6e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain Med13_C PF06333.12 RKO96667.1 - 0.099 11.9 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Branch PF02485.21 RKO96668.1 - 0.0042 16.6 0.2 0.026 14.0 0.0 2.2 2 0 0 2 2 2 1 Core-2/I-Branching enzyme DUF1690 PF07956.11 RKO96668.1 - 7.5 7.0 6.6 1.3 9.4 0.2 2.6 3 0 0 3 3 3 0 Protein of Unknown function (DUF1690) DUF737 PF05300.11 RKO96669.1 - 0.022 15.1 3.4 0.037 14.4 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) FYDLN_acid PF09538.10 RKO96669.1 - 0.042 14.5 4.6 0.055 14.1 3.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) DUF2407_C PF13373.6 RKO96669.1 - 0.042 14.0 0.0 0.066 13.4 0.0 1.2 1 0 0 1 1 1 0 DUF2407 C-terminal domain TEX13 PF15186.6 RKO96669.1 - 1.1 9.0 5.8 1.8 8.2 5.8 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family DUF2514 PF10721.9 RKO96669.1 - 3.8 7.5 17.6 7.9 6.5 17.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DUF2423 PF10338.9 RKO96672.1 - 2.3e-12 46.9 2.8 2.3e-12 46.9 2.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Laps PF10169.9 RKO96672.1 - 0.55 10.8 6.0 1.2 9.7 6.0 1.8 1 1 0 1 1 1 0 Learning-associated protein Roughex PF06020.11 RKO96673.1 - 3.4 6.7 7.0 5.1 6.1 5.6 1.8 1 1 1 2 2 2 0 Drosophila roughex protein Dus PF01207.17 RKO96674.1 - 7.1e-71 238.8 0.1 8.7e-71 238.5 0.1 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 RKO96674.1 - 0.054 12.7 0.0 0.071 12.3 0.0 1.1 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.15 RKO96674.1 - 0.094 12.1 0.3 0.33 10.3 0.2 1.8 1 1 1 2 2 2 0 Nitronate monooxygenase F-box-like PF12937.7 RKO96675.1 - 4.4e-06 26.5 0.3 1.2e-05 25.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 RKO96675.1 - 6.5e-05 22.7 0.2 0.00021 21.1 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 RKO96675.1 - 0.00085 19.2 0.1 0.0024 17.8 0.1 1.7 1 0 0 1 1 1 1 F-box RVP_2 PF08284.11 RKO96676.1 - 0.01 15.6 0.0 0.01 15.6 0.0 1.0 1 0 0 1 1 1 0 Retroviral aspartyl protease Ribosomal_S19e PF01090.19 RKO96678.1 - 3e-53 179.2 0.1 3.3e-53 179.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HTH_41 PF14502.6 RKO96678.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Tmemb_14 PF03647.13 RKO96680.1 - 0.0018 19.0 0.2 0.0037 18.0 0.2 1.5 1 0 0 1 1 1 1 Transmembrane proteins 14C ABC_membrane PF00664.23 RKO96680.1 - 0.011 15.5 3.2 0.017 14.8 3.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region Trypan_PARP PF05887.11 RKO96680.1 - 0.27 11.2 11.3 0.53 10.3 11.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Tom5 PF10642.9 RKO96680.1 - 4.2 7.5 8.4 0.41 10.7 0.3 3.1 3 0 0 3 3 3 0 Mitochondrial import receptor subunit or translocase DUF3915 PF13054.6 RKO96681.1 - 2.2e-05 24.4 3.5 2.2e-05 24.4 3.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3915) Tubulin PF00091.25 RKO96682.1 - 5.5e-69 232.3 0.0 9.7e-69 231.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RKO96682.1 - 1.1e-43 148.4 0.1 1.7e-43 147.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 RKO96682.1 - 1e-05 25.8 0.0 2.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 RKO96682.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 RKO96682.1 - 0.023 13.9 0.0 0.055 12.6 0.0 1.6 2 0 0 2 2 2 0 Tubulin like gag_pre-integrs PF13976.6 RKO96683.1 - 6.7e-07 29.1 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Med17 PF10156.9 RKO96684.1 - 1.7e-07 30.3 0.0 2.1e-05 23.5 0.0 2.2 2 0 0 2 2 2 2 Subunit 17 of Mediator complex Pyr_redox_2 PF07992.14 RKO96685.1 - 7.6e-54 182.9 0.0 9.4e-54 182.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO96685.1 - 2.5e-11 43.9 0.0 2.9e-09 37.4 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKO96685.1 - 0.00019 20.8 0.1 0.41 9.9 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 RKO96685.1 - 0.0019 18.2 0.7 7.1 6.6 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 RKO96685.1 - 0.0063 16.1 0.4 6.1 6.3 0.0 3.3 3 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 RKO96685.1 - 0.051 12.3 2.1 0.25 10.0 0.0 2.6 2 1 1 3 3 3 0 HI0933-like protein CRAL_TRIO PF00650.20 RKO96686.1 - 1.2e-32 112.9 0.1 1.3e-32 112.7 0.1 1.0 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 RKO96686.1 - 0.00051 20.2 0.0 0.00065 19.9 0.0 1.1 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF5478 PF17572.2 RKO96686.1 - 0.087 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5478) ZapD PF07072.11 RKO96687.1 - 0.0048 16.7 2.6 1.3 8.7 0.0 3.0 2 1 1 4 4 4 2 Cell division protein Atg14 PF10186.9 RKO96687.1 - 0.34 9.9 5.0 0.12 11.5 1.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM184 PF15665.5 RKO96687.1 - 1.6 8.5 8.4 0.037 13.8 1.0 2.0 2 1 0 2 2 2 0 Family with sequence similarity 184, A and B Transketolase_N PF00456.21 RKO96688.1 - 8.8e-151 501.6 0.2 1.1e-150 501.3 0.2 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 RKO96688.1 - 2.1e-26 92.7 0.0 3.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 RKO96688.1 - 9e-06 25.1 0.0 4.2e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 RKO96688.1 - 0.023 14.5 0.7 0.11 12.3 0.7 2.0 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_M49 PF03571.15 RKO96688.1 - 0.087 11.2 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M49 Pkinase PF00069.25 RKO96690.1 - 1.4e-71 240.9 0.0 1.6e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96690.1 - 1.8e-35 122.5 0.0 2.9e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO96690.1 - 0.0037 16.7 0.1 0.0073 15.7 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO96690.1 - 0.0039 17.2 0.0 0.091 12.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF2322 PF10084.9 RKO96690.1 - 0.13 12.3 0.0 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) WD40 PF00400.32 RKO96691.1 - 7.1e-09 36.2 3.0 0.37 11.7 0.0 6.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO96691.1 - 0.00048 20.4 0.0 1.6 9.1 0.0 3.9 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PDCD2_C PF04194.13 RKO96692.1 - 2.1e-22 80.0 3.3 2.9e-22 79.6 0.8 2.5 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain RNA_pol_Rpb2_1 PF04563.15 RKO96695.1 - 1.6e-50 171.4 0.0 1.8e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 RKO96695.1 - 5.8e-18 65.2 0.0 1e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 RKO96696.1 - 1.4e-21 76.5 0.0 2.2e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 RKO96696.1 - 3.8e-05 23.9 0.1 9.1e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 PHC2_SAM_assoc PF16616.5 RKO96697.1 - 2.3 9.0 6.6 0.13 13.1 1.0 1.7 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Acatn PF13000.7 RKO96698.1 - 1.9e-124 416.2 23.9 1.8e-85 287.5 15.2 3.7 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 SdpI PF13630.6 RKO96698.1 - 7.4 6.8 7.9 5.6 7.2 0.3 3.3 3 0 0 3 3 3 0 SdpI/YhfL protein family HMMR_N PF15905.5 RKO96699.1 - 0.0054 16.2 22.2 0.0054 16.2 22.2 5.6 2 1 3 6 6 6 2 Hyaluronan mediated motility receptor N-terminal TMF_DNA_bd PF12329.8 RKO96699.1 - 0.0059 16.6 0.7 0.0059 16.6 0.7 8.7 5 3 3 10 10 10 4 TATA element modulatory factor 1 DNA binding Spc7 PF08317.11 RKO96699.1 - 0.0092 14.9 113.7 0.0057 15.6 12.7 5.1 1 1 4 5 5 5 4 Spc7 kinetochore protein Hydrolase PF00702.26 RKO96700.1 - 3.6e-10 40.5 0.0 0.00018 21.9 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 RKO96700.1 - 3.6e-05 23.6 4.8 5.9e-05 22.9 4.8 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 RKO96700.1 - 0.012 15.4 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKO96700.1 - 0.027 14.6 0.0 0.052 13.6 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) B12D PF06522.11 RKO96701.1 - 1.9e-13 50.0 0.1 1.9e-13 50.0 0.1 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RhoGEF PF00621.20 RKO96702.1 - 8.7e-47 159.7 0.1 1.2e-46 159.3 0.1 1.2 1 0 0 1 1 1 1 RhoGEF domain SH3_2 PF07653.17 RKO96702.1 - 4.4e-08 32.7 0.0 9e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO96702.1 - 1.3e-06 27.9 0.1 2.9e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 RKO96702.1 - 2.8e-06 27.1 0.2 5.6e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ_SEC7_PH PF16453.5 RKO96702.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 PH domain HSP20 PF00011.21 RKO96703.1 - 8e-06 25.9 0.0 1e-05 25.6 0.0 1.3 1 1 0 1 1 1 1 Hsp20/alpha crystallin family DUF4381 PF14316.6 RKO96705.1 - 0.013 15.7 4.0 0.022 15.0 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) LPG_synthase_TM PF03706.13 RKO96705.1 - 0.094 12.2 1.2 0.11 12.0 1.2 1.2 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region Phage_Gp23 PF10669.9 RKO96705.1 - 0.12 12.7 0.1 0.21 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Adeno_E3_CR2 PF02439.15 RKO96705.1 - 0.13 12.0 0.3 0.2 11.4 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 LapA_dom PF06305.11 RKO96705.1 - 1.3 8.9 5.9 25 4.8 5.9 2.2 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Pkinase PF00069.25 RKO96709.1 - 8.9e-23 81.0 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96709.1 - 1.7e-14 53.8 0.0 2.9e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO96709.1 - 0.029 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DHHC PF01529.20 RKO96710.1 - 2.6e-32 111.7 11.5 2.6e-32 111.7 11.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Trep_Strep PF09605.10 RKO96710.1 - 0.32 11.0 11.5 0.12 12.4 3.3 2.8 2 1 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF2244 PF10003.9 RKO96710.1 - 0.51 10.0 2.9 0.67 9.6 0.3 2.3 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3789 PF12664.7 RKO96710.1 - 2.5 7.9 6.9 4.6 7.0 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3789) Piwi PF02171.17 RKO96711.1 - 4.4e-96 321.7 0.0 5.9e-96 321.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 RKO96711.1 - 9.4e-17 61.1 0.0 1.7e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 RKO96711.1 - 7.2e-13 48.0 0.0 1.7e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 RKO96711.1 - 1e-10 41.7 0.0 2.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 RKO96711.1 - 3.4e-09 36.9 0.0 7.8e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain RST PF12174.8 RKO96712.1 - 0.21 11.6 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain FBPase PF00316.20 RKO96713.1 - 1.2e-71 240.1 0.1 1.6e-71 239.7 0.1 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 RKO96713.1 - 0.024 14.2 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Inositol monophosphatase family adh_short PF00106.25 RKO96714.1 - 7.7e-11 41.8 0.0 9.6e-11 41.5 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO96714.1 - 1.5e-06 28.0 0.0 1.8e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Vinculin PF01044.19 RKO96715.1 - 3.1e-25 88.7 26.3 2.5e-19 69.1 4.1 3.1 2 1 1 3 3 3 3 Vinculin family Syja_N PF02383.18 RKO96717.1 - 1.8e-76 257.5 0.0 2.4e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain OPA3 PF07047.12 RKO96718.1 - 9.9e-43 144.9 0.2 1.2e-42 144.6 0.2 1.0 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DivIC PF04977.15 RKO96718.1 - 0.0084 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Septum formation initiator MerR-DNA-bind PF09278.11 RKO96718.1 - 0.086 13.4 0.5 0.18 12.4 0.5 1.5 1 0 0 1 1 1 0 MerR, DNA binding SLT PF01464.20 RKO96718.1 - 0.098 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain DNA_repr_REX1B PF14966.6 RKO96719.1 - 2.5e-07 31.3 0.0 0.00026 21.6 0.0 2.2 2 0 0 2 2 2 2 DNA repair REX1-B PepSY_2 PF13670.6 RKO96719.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain dCache_1 PF02743.18 RKO96720.1 - 5.3e-11 42.8 4.8 2.6e-10 40.5 4.8 1.9 1 1 0 1 1 1 1 Cache domain DUF5122 PF17164.4 RKO96720.1 - 0.079 13.3 0.1 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Ribosomal_S8 PF00410.19 RKO96722.1 - 4.2e-20 72.0 0.0 3.7e-19 68.9 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8 HemY_N PF07219.13 RKO96723.1 - 0.00013 22.2 1.8 0.0046 17.1 0.0 2.6 2 0 0 2 2 2 1 HemY protein N-terminus DUF4834 PF16118.5 RKO96723.1 - 0.016 16.2 0.1 0.45 11.5 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF3302 PF11742.8 RKO96723.1 - 0.069 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) MAP17 PF15807.5 RKO96723.1 - 0.13 12.5 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 RKO96723.1 - 0.49 10.1 1.7 4.1 7.1 0.0 2.8 3 0 0 3 3 3 0 FAM176 family Esterase PF00756.20 RKO96724.1 - 3.9e-47 161.0 0.0 4.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 RKO96724.1 - 2.8e-09 36.8 1.0 1.4e-08 34.5 1.0 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 RKO96724.1 - 0.00052 19.4 0.1 0.0016 17.8 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 RKO96724.1 - 0.00094 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 RKO96724.1 - 0.0037 16.8 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 RKO96724.1 - 0.0056 15.7 0.0 0.0085 15.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Lipase_3 PF01764.25 RKO96724.1 - 0.017 15.0 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 RKO96724.1 - 1.3 9.5 9.5 1.7 9.2 8.7 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family GDP_Man_Dehyd PF16363.5 RKO96726.1 - 5.5e-67 226.5 0.0 6.4e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 RKO96726.1 - 7.7e-61 205.6 0.1 9.5e-61 205.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 RKO96726.1 - 3.5e-24 85.4 0.0 5.3e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RKO96726.1 - 2.1e-20 72.9 0.0 2.6e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RKO96726.1 - 1.3e-19 70.4 0.6 4.7e-18 65.3 0.6 2.7 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 RKO96726.1 - 3.2e-18 65.8 0.0 6.4e-18 64.9 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 RKO96726.1 - 6.4e-07 29.4 0.0 1.6e-06 28.1 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 RKO96726.1 - 0.00038 20.0 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase DKCLD PF08068.12 RKO96726.1 - 0.12 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 DKCLD (NUC011) domain Clat_adaptor_s PF01217.20 RKO96727.1 - 4.2e-55 185.6 1.8 4.6e-55 185.5 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Glyoxalase PF00903.25 RKO96728.1 - 1.5e-23 83.4 0.3 4.1e-15 56.1 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 RKO96728.1 - 3.5e-12 46.6 0.0 8.8e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 RKO96728.1 - 4.1e-07 30.2 0.0 1.2e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 RKO96728.1 - 1.4e-06 28.5 0.2 0.094 12.8 0.0 3.2 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 RKO96728.1 - 0.0054 17.5 0.1 0.36 11.6 0.3 2.5 2 1 0 2 2 2 1 Glyoxalase-like domain eIF-3c_N PF05470.12 RKO96729.1 - 3.2e-146 488.1 0.7 4.1e-146 487.7 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 RKO96729.1 - 7.8e-12 45.6 0.2 8e-10 39.2 0.0 2.9 2 0 0 2 2 2 1 PCI domain T3SS_needle_E PF08988.10 RKO96729.1 - 0.076 13.2 0.7 15 5.9 0.0 3.7 4 0 0 4 4 4 0 Type III secretion system, cytoplasmic E component of needle Sigma70_ner PF04546.13 RKO96729.1 - 0.15 11.9 6.6 1.8 8.4 0.6 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF3402 PF11882.8 RKO96729.1 - 0.58 9.2 3.3 0.65 9.0 2.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3402) RNA_pol PF00940.19 RKO96730.1 - 7.5e-52 176.6 0.2 8.2e-52 176.4 0.2 1.0 1 0 0 1 1 1 1 DNA-dependent RNA polymerase AD PF09793.9 RKO96730.1 - 0.25 11.5 1.1 1.9 8.7 0.2 2.2 1 1 1 2 2 2 0 Anticodon-binding domain fn3 PF00041.21 RKO96731.1 - 2.4e-17 63.0 0.2 0.00031 21.0 0.0 4.8 4 0 0 4 4 4 3 Fibronectin type III domain Lebercilin PF15619.6 RKO96731.1 - 6.2e-08 32.5 17.2 6.2e-08 32.5 17.2 1.5 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Pur_ac_phosph_N PF16656.5 RKO96731.1 - 0.0016 18.9 0.1 17 6.0 0.0 3.7 3 0 0 3 3 3 0 Purple acid Phosphatase, N-terminal domain DUF2369 PF10179.9 RKO96731.1 - 0.0041 17.5 1.8 4.8 7.6 0.0 4.0 5 0 0 5 5 5 1 Uncharacterised conserved protein (DUF2369) TRAF_BIRC3_bd PF16673.5 RKO96731.1 - 0.026 14.3 0.8 0.026 14.3 0.8 3.0 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF641 PF04859.12 RKO96731.1 - 0.5 10.7 12.0 2.6 8.4 3.9 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF1192 PF06698.11 RKO96731.1 - 1.5 8.9 5.7 11 6.2 1.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) APG6_N PF17675.1 RKO96731.1 - 1.7 9.2 16.3 0.17 12.4 6.9 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 RKO96731.1 - 2.6 6.5 5.7 1 7.9 3.1 1.5 1 1 1 2 2 2 0 Flagellar Assembly Protein A TMCO5 PF14992.6 RKO96731.1 - 3.8 7.0 8.5 0.61 9.6 3.6 1.9 1 1 1 2 2 2 0 TMCO5 family Fib_alpha PF08702.10 RKO96731.1 - 9.4 6.4 10.1 0.3 11.3 3.2 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Thioredoxin PF00085.20 RKO96733.1 - 2e-16 59.9 0.2 2.4e-16 59.6 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 RKO96733.1 - 0.0017 17.4 0.0 0.0021 17.0 0.0 1.0 1 0 0 1 1 1 1 Phosducin OST3_OST6 PF04756.13 RKO96733.1 - 0.073 12.4 0.0 0.081 12.3 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family LMBR1 PF04791.16 RKO96734.1 - 1.6 7.5 10.6 2.5 6.9 10.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein LRR_8 PF13855.6 RKO96735.1 - 1.8e-11 43.6 2.6 9.2e-05 22.1 0.1 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 RKO96735.1 - 2e-06 28.0 7.9 0.00023 21.5 1.5 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RKO96735.1 - 0.0015 18.1 0.2 0.0028 17.2 0.2 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 RKO96735.1 - 0.0098 16.3 2.0 15 6.6 0.1 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat DUF2116 PF09889.9 RKO96735.1 - 0.24 11.4 1.7 0.43 10.6 1.7 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) YHS PF04945.13 RKO96735.1 - 0.79 9.9 2.6 0.7 10.0 1.3 1.6 2 0 0 2 2 2 0 YHS domain LRR_6 PF13516.6 RKO96735.1 - 1 9.6 4.1 11 6.4 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeat SUIM_assoc PF16619.5 RKO96735.1 - 1.1 9.4 11.8 0.12 12.4 4.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 EAP30 PF04157.16 RKO96736.1 - 4.8e-66 222.4 0.0 5.4e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family EutK_C PF16365.5 RKO96736.1 - 0.0032 17.5 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilization protein EutK C-terminus Metallophos PF00149.28 RKO96737.1 - 1.8e-33 116.7 0.1 2.4e-33 116.4 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PUA PF01472.20 RKO96738.1 - 0.0075 16.2 0.7 0.014 15.3 0.7 1.4 1 0 0 1 1 1 1 PUA domain Lyase_1 PF00206.20 RKO96739.1 - 1.4e-92 310.5 0.0 3.5e-92 309.1 0.0 1.6 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.6 RKO96739.1 - 3.3e-23 82.2 0.3 8.3e-23 80.9 0.3 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Tma16 PF11176.8 RKO96740.1 - 3.3e-20 72.5 0.0 3.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Cep57_CLD PF14073.6 RKO96741.1 - 1.1e-08 35.3 13.2 3.9e-05 23.8 0.2 2.8 3 0 0 3 3 3 2 Centrosome localisation domain of Cep57 FPP PF05911.11 RKO96741.1 - 0.31 9.2 6.1 0.07 11.3 0.5 2.0 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil CENP-F_leu_zip PF10473.9 RKO96741.1 - 4.9 7.2 9.6 2.4 8.2 4.4 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 RKO96741.1 - 8.7 5.8 8.9 0.63 9.6 3.1 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit FAM76 PF16046.5 RKO96742.1 - 0.047 13.1 0.7 0.055 12.8 0.7 1.1 1 0 0 1 1 1 0 FAM76 protein TolA_bind_tri PF16331.5 RKO96742.1 - 0.13 12.4 2.1 0.2 11.8 1.3 1.7 1 1 0 1 1 1 0 TolA binding protein trimerisation FeS_assembly_P PF01883.19 RKO96744.1 - 3.2e-16 59.3 0.1 5.4e-16 58.5 0.1 1.4 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein CDC50 PF03381.15 RKO96745.1 - 7.1e-82 275.1 0.0 8.5e-82 274.8 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Prefoldin PF02996.17 RKO96746.1 - 6.4e-12 45.4 0.0 6.7e-12 45.4 0.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit SlyX PF04102.12 RKO96749.1 - 0.29 11.8 7.8 1.5 9.5 7.8 2.4 1 0 0 1 1 1 0 SlyX YlqD PF11068.8 RKO96749.1 - 0.55 10.6 4.9 0.21 11.9 2.0 1.8 2 0 0 2 2 2 0 YlqD protein DELLA PF12041.8 RKO96749.1 - 1.6 8.7 4.0 1.3 9.0 1.5 2.1 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Chorismate_bind PF00425.18 RKO96750.1 - 6.4e-100 334.0 0.0 3.1e-99 331.7 0.0 1.9 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 RKO96750.1 - 1e-31 110.1 0.6 1.6e-26 93.2 0.1 3.9 2 2 0 2 2 2 2 Anthranilate synthase component I, N terminal region PDH PF02153.17 RKO96750.1 - 0.14 11.2 0.0 0.34 9.9 0.1 1.6 2 0 0 2 2 2 0 Prephenate dehydrogenase CENP-T_C PF15511.6 RKO96752.1 - 1.1e-08 35.1 0.1 1.3e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 RKO96752.1 - 5.5e-05 23.5 0.4 6.3e-05 23.3 0.4 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RKO96752.1 - 6e-05 23.3 0.1 9.8e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.17 RKO96752.1 - 0.00026 21.1 0.1 0.00035 20.7 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 RKO96752.1 - 0.00062 20.1 0.1 0.00079 19.8 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 RKO96752.1 - 0.0033 17.4 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 RKO96752.1 - 0.028 14.5 0.0 0.031 14.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit KCNQ2_u3 PF16642.5 RKO96753.1 - 0.65 11.0 4.2 1.7 9.7 4.2 1.7 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 TFIIA PF03153.13 RKO96753.1 - 1.4 8.8 18.5 2.5 8.0 18.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Smg8_Smg9 PF10220.9 RKO96753.1 - 1.7 6.8 5.9 2.5 6.3 5.9 1.1 1 0 0 1 1 1 0 Smg8_Smg9 SUIM_assoc PF16619.5 RKO96753.1 - 6.9 6.8 12.5 36 4.5 12.5 2.1 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF3446 PF11928.8 RKO96754.1 - 0.29 11.5 6.0 0.5 10.7 6.0 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain MarC PF01914.17 RKO96755.1 - 1.7 8.0 8.5 0.46 9.8 4.8 1.8 2 0 0 2 2 2 0 MarC family integral membrane protein Carn_acyltransf PF00755.20 RKO96756.1 - 1e-185 618.8 0.0 1.1e-185 618.6 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_11 PF13086.6 RKO96757.1 - 5.4e-10 39.5 0.0 5.7e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO96757.1 - 9.9e-08 32.4 0.0 1e-07 32.4 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO96757.1 - 3.2e-06 27.0 0.0 3.4e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RKO96757.1 - 0.0043 16.6 0.0 0.0046 16.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKO96757.1 - 0.0052 17.1 0.0 0.0057 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 RKO96757.1 - 0.0071 16.4 0.0 0.0076 16.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RKO96757.1 - 0.0088 16.4 0.0 0.0098 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 RKO96757.1 - 0.011 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 RKO96757.1 - 0.013 15.9 0.3 0.047 14.1 0.2 1.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 RKO96757.1 - 0.013 15.2 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 RKO96757.1 - 0.017 15.5 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 RKO96757.1 - 0.037 14.0 0.1 0.056 13.4 0.0 1.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 RKO96757.1 - 0.045 13.3 0.0 0.047 13.2 0.0 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RsgA_GTPase PF03193.16 RKO96757.1 - 0.069 13.1 0.0 0.1 12.5 0.0 1.3 1 1 0 1 1 1 0 RsgA GTPase PhoH PF02562.16 RKO96757.1 - 0.074 12.5 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 RKO96757.1 - 0.094 12.9 0.0 0.11 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 RKO96757.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Helicase DUF2075 PF09848.9 RKO96757.1 - 0.13 11.5 0.0 0.14 11.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Torsin PF06309.11 RKO96757.1 - 0.15 12.2 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.6 RKO96757.1 - 0.21 12.1 0.0 0.26 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_12 PF13087.6 RKO96758.1 - 7.4e-12 45.3 0.0 8.7e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 RKO96759.1 - 9.8e-18 64.5 0.6 1e-17 64.4 0.6 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 RKO96759.1 - 0.00054 19.7 0.1 0.0011 18.8 0.1 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 RKO96759.1 - 0.0085 15.9 0.0 0.009 15.8 0.0 1.0 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 RKO96759.1 - 0.049 12.9 1.0 0.08 12.2 0.3 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Histone PF00125.24 RKO96761.1 - 9.2e-49 165.1 2.9 1e-48 165.0 2.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 RKO96761.1 - 3.5e-05 24.4 1.2 4.1e-05 24.2 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 RKO96761.1 - 7.1e-05 23.1 0.1 0.0001 22.6 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 RKO96761.1 - 9.9e-05 22.4 0.2 9.9e-05 22.4 0.2 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 RKO96761.1 - 0.0062 16.8 0.1 0.014 15.6 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 RKO96761.1 - 0.044 13.9 0.2 0.079 13.0 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RKO96761.1 - 0.094 12.7 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF4477 PF14780.6 RKO96762.1 - 8.4e-14 51.6 0.3 2.3e-08 33.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4477) DUF3138 PF11336.8 RKO96763.1 - 0.059 12.0 9.5 0.097 11.3 8.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF4400 PF14348.6 RKO96763.1 - 0.076 12.5 0.2 0.21 11.1 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) OppC_N PF12911.7 RKO96763.1 - 0.48 10.4 1.9 0.68 10.0 0.3 2.0 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Aurora-A_bind PF09041.10 RKO96764.1 - 0.041 14.0 0.1 0.068 13.2 0.1 1.3 1 0 0 1 1 1 0 Aurora-A binding SHMT PF00464.19 RKO96766.1 - 2e-165 550.3 0.0 2.5e-165 549.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase ABC_membrane PF00664.23 RKO96767.1 - 5.2e-48 164.1 3.6 7.3e-48 163.6 3.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RKO96767.1 - 7.6e-34 117.2 0.0 1.4e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RKO96767.1 - 0.00046 19.7 1.3 0.018 14.5 0.1 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RKO96767.1 - 0.00066 18.6 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 RKO96767.1 - 0.00069 19.9 0.1 0.011 16.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 RKO96767.1 - 0.0065 15.8 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 RKO96767.1 - 0.009 16.4 0.5 0.074 13.4 0.5 2.2 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 RKO96767.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 RKO96767.1 - 0.12 12.3 0.1 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 RKO96767.1 - 0.12 12.1 0.0 0.72 9.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 RKO96767.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NDUFB10 PF10249.9 RKO96768.1 - 0.006 17.1 0.3 0.0061 17.1 0.3 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 TRAPP PF04051.16 RKO96769.1 - 2.8e-28 98.5 0.0 3.3e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Biopterin_H PF00351.21 RKO96770.1 - 9.5e-147 488.3 0.0 1.1e-146 488.1 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 RKO96770.1 - 3.9e-06 26.5 0.0 7.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 RKO96770.1 - 0.0041 17.7 0.0 0.0066 17.0 0.0 1.3 1 0 0 1 1 1 1 ACT domain Glyco_transf_22 PF03901.17 RKO96771.1 - 1.6e-28 100.1 0.0 2.1e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SUR7 PF06687.12 RKO96772.1 - 5.5e-13 49.0 15.5 7.2e-13 48.7 15.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Spt20 PF12090.8 RKO96772.1 - 0.33 10.5 21.4 0.53 9.9 21.4 1.2 1 0 0 1 1 1 0 Spt20 family DUF2207 PF09972.9 RKO96772.1 - 0.65 8.7 8.0 0.051 12.3 1.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) TFIIA PF03153.13 RKO96772.1 - 4.6 7.1 22.2 6.7 6.6 22.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3341 PF11821.8 RKO96772.1 - 7.8 6.1 6.0 1.2 8.7 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) Pox_A31 PF05771.11 RKO96775.1 - 0.18 11.8 0.1 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A31 protein Ribosomal_60s PF00428.19 RKO96776.1 - 2.1e-23 82.7 8.3 2.6e-23 82.4 8.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3824 PF12868.7 RKO96776.1 - 2.9 8.5 4.8 4 8.1 4.8 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Sacchrp_dh_NADP PF03435.18 RKO96778.1 - 7.6e-14 52.1 0.1 1.2e-13 51.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 RKO96778.1 - 1.8e-05 24.7 0.1 3.4e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Phageshock_PspD PF09584.10 RKO96780.1 - 0.18 11.8 0.6 0.28 11.2 0.6 1.3 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) TPR_2 PF07719.17 RKO96781.1 - 4.9e-21 73.1 0.3 1e-05 25.3 0.0 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 RKO96781.1 - 2.2e-19 68.4 0.0 2.7e-06 27.0 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 RKO96781.1 - 6.9e-16 58.5 1.6 0.00014 22.3 0.1 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 RKO96781.1 - 1.7e-14 53.3 10.4 0.0011 19.6 0.0 6.4 1 1 6 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 RKO96781.1 - 1.5e-11 43.8 0.1 0.33 11.4 0.0 6.4 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKO96781.1 - 2.1e-10 40.7 8.0 0.0014 18.8 0.1 4.8 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 RKO96781.1 - 2e-09 38.0 6.9 0.0085 16.7 0.1 4.1 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 RKO96781.1 - 1.2e-08 34.5 0.1 0.00035 20.2 0.0 4.3 1 1 3 4 4 4 2 TPR repeat TPR_8 PF13181.6 RKO96781.1 - 1.4e-08 34.3 0.0 0.0085 16.2 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO96781.1 - 3.7e-08 33.5 1.4 0.32 11.7 0.0 6.1 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO96781.1 - 1.5e-06 28.2 11.4 0.0048 17.0 0.6 3.7 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO96781.1 - 7.7e-06 26.0 1.5 0.007 16.6 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 RKO96781.1 - 1.3e-05 24.6 0.7 0.043 13.0 0.0 3.3 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKO96781.1 - 6.2e-05 22.7 2.3 0.18 11.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RKO96781.1 - 7.3e-05 22.4 2.0 0.00055 19.6 0.1 2.8 2 1 1 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) DUF4192 PF13830.6 RKO96781.1 - 0.0007 19.7 9.3 0.54 10.3 0.5 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4192) TPR_MalT PF17874.1 RKO96781.1 - 0.0021 17.5 5.7 0.25 10.7 0.2 2.6 2 1 1 3 3 3 2 MalT-like TPR region TPR_10 PF13374.6 RKO96781.1 - 0.011 15.6 4.2 11 6.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 RKO96781.1 - 0.046 12.7 0.0 0.076 12.0 0.0 1.3 1 1 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_21 PF09976.9 RKO96781.1 - 0.082 12.6 0.2 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Coatomer_E PF04733.14 RKO96781.1 - 0.083 12.3 0.0 1.4 8.2 0.0 2.1 1 1 1 2 2 2 0 Coatomer epsilon subunit Glyco_transf_92 PF01697.27 RKO96782.1 - 2.6e-17 63.3 1.5 7.2e-17 61.9 1.5 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 RKO96782.1 - 5e-07 30.1 0.6 5.6e-06 26.8 0.3 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 2 ATP-synt_DE PF00401.20 RKO96782.1 - 0.83 10.0 5.3 0.51 10.7 2.1 2.3 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Pkinase PF00069.25 RKO96783.1 - 2.6e-34 118.8 0.0 3e-34 118.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96783.1 - 6.8e-10 38.7 0.0 8.7e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO96783.1 - 0.014 14.7 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO96783.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RKO96783.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CLTH PF10607.9 RKO96785.1 - 2.4e-31 108.6 0.1 3.3e-31 108.2 0.1 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Glyco_trans_4_5 PF16994.5 RKO96785.1 - 0.037 13.6 0.5 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 Glycosyl-transferase family 4 PknH_C PF14032.6 RKO96786.1 - 0.0062 16.4 0.5 0.011 15.5 0.5 1.4 1 0 0 1 1 1 1 PknH-like extracellular domain DUF2156 PF09924.9 RKO96786.1 - 0.016 14.2 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2156) Mito_carr PF00153.27 RKO96787.1 - 2e-66 220.0 7.4 2.4e-24 85.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4684 PF15736.5 RKO96787.1 - 0.07 11.8 0.0 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Fuseless PF15993.5 RKO96787.1 - 0.096 11.9 0.1 0.26 10.5 0.1 1.6 2 0 0 2 2 2 0 Fuseless AlaDh_PNT_N PF05222.15 RKO96788.1 - 6.7e-26 91.2 0.0 7.7e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Tax PF02959.16 RKO96788.1 - 0.088 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 HTLV Tax Ribosomal_L24e PF01246.20 RKO96789.1 - 1.5e-27 95.6 0.2 1.5e-27 95.6 0.2 1.9 3 0 0 3 3 3 1 Ribosomal protein L24e HMG_box PF00505.19 RKO96790.1 - 6.8e-18 64.9 0.8 1e-17 64.3 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKO96790.1 - 8.1e-06 26.3 0.2 1.3e-05 25.7 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain HEAT PF02985.22 RKO96791.1 - 1.6e-08 34.1 26.8 0.028 14.7 1.1 8.5 9 0 0 9 9 8 2 HEAT repeat ParcG PF10274.9 RKO96791.1 - 0.00038 20.6 0.6 0.075 13.2 0.1 3.4 3 0 0 3 3 3 1 Parkin co-regulated protein TAF6_C PF07571.13 RKO96791.1 - 0.0014 19.0 2.1 6 7.3 0.0 4.6 3 1 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain BUD22 PF09073.10 RKO96791.1 - 0.0074 15.7 7.3 0.015 14.7 7.3 1.4 1 0 0 1 1 1 1 BUD22 Xpo1 PF08389.12 RKO96791.1 - 0.009 16.1 0.0 0.37 10.8 0.0 3.2 2 1 0 2 2 2 1 Exportin 1-like protein DUF3437 PF11919.8 RKO96791.1 - 0.01 15.8 0.7 1.2 9.1 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) MMS19_C PF12460.8 RKO96791.1 - 0.014 14.6 5.0 0.071 12.2 0.0 3.9 4 0 0 4 4 4 0 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 RKO96791.1 - 0.015 15.4 4.3 0.67 10.0 0.0 4.3 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 RKO96791.1 - 0.041 13.6 7.4 25 4.5 0.2 5.0 5 1 0 5 5 5 0 rRNA processing/ribosome biogenesis RACo_linker PF17650.1 RKO96791.1 - 0.053 13.4 2.5 0.66 9.9 0.1 3.2 3 0 0 3 3 2 0 RACo linker region HEAT_2 PF13646.6 RKO96791.1 - 0.17 12.3 30.5 0.07 13.5 1.2 7.2 4 2 3 7 7 7 0 HEAT repeats DUF3384 PF11864.8 RKO96791.1 - 0.23 10.3 2.7 5.5 5.8 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3384) Sigma70_ner PF04546.13 RKO96791.1 - 0.31 10.9 16.5 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region GCIP PF13324.6 RKO96791.1 - 0.36 10.4 10.0 1.1 8.9 4.1 2.3 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting TFIIF_alpha PF05793.12 RKO96791.1 - 2.3 6.7 11.8 0.18 10.4 0.3 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Proteasom_PSMB PF10508.9 RKO96791.1 - 2.7 6.4 5.6 1.5 7.2 0.5 3.0 3 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 RKO96791.1 - 5.6 7.6 24.7 2.1 8.9 0.6 8.5 8 1 1 9 9 9 0 HEAT-like repeat Astro_capsid_p PF12226.8 RKO96791.1 - 7.4 5.6 16.2 5.8 6.0 8.4 2.3 2 0 0 2 2 2 0 Turkey astrovirus capsid protein DUF4042 PF13251.6 RKO96791.1 - 8.1 6.1 10.4 8.9 6.0 0.0 4.9 5 1 0 6 6 6 0 Domain of unknown function (DUF4042) Snf7 PF03357.21 RKO96793.1 - 1.3e-37 129.0 14.8 1.5e-37 128.8 14.8 1.0 1 0 0 1 1 1 1 Snf7 Fe_dep_repr_C PF02742.15 RKO96793.1 - 0.021 14.9 0.2 0.044 13.9 0.2 1.7 1 1 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain MscS_TM PF12794.7 RKO96793.1 - 1.1 8.1 3.6 1.4 7.7 3.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 E1_dh PF00676.20 RKO96794.1 - 1.5e-63 214.5 0.0 2.1e-63 214.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 RKO96794.1 - 8.1e-63 211.3 0.0 1.3e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 RKO96794.1 - 1.3e-41 141.8 0.1 6.6e-33 113.6 0.0 3.4 3 0 0 3 3 3 3 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 RKO96794.1 - 2.1e-18 65.6 1.6 2.4e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus RIIa PF02197.17 RKO96795.1 - 7.3e-15 54.4 3.1 1.4e-14 53.5 3.1 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit WD40 PF00400.32 RKO96796.1 - 5.4e-10 39.7 11.4 0.033 15.1 0.1 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Drf_GBD PF06371.13 RKO96797.1 - 6.9e-12 45.3 0.0 0.01 15.4 0.0 4.6 4 0 0 4 4 4 4 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 RKO96797.1 - 2.2e-05 24.1 0.4 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Thymidylate_kin PF02223.17 RKO96797.1 - 0.024 14.3 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase DUF3636 PF12331.8 RKO96797.1 - 0.091 12.6 0.1 7.8 6.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3636) HLH PF00010.26 RKO96800.1 - 7.2e-15 54.7 4.3 7.2e-15 54.7 4.3 2.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF2574 PF10836.8 RKO96802.1 - 0.2 11.6 3.0 0.71 9.8 3.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2574) DEC-1_N PF04625.13 RKO96804.1 - 0.025 13.6 3.6 0.026 13.5 3.6 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Aldose_epim PF01263.20 RKO96805.1 - 2e-18 66.8 0.0 2.1e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Cpn60_TCP1 PF00118.24 RKO96807.1 - 1.2e-162 542.0 3.0 1.3e-162 541.8 3.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.16 RKO96807.1 - 0.39 10.9 2.7 25 5.0 0.0 3.3 3 0 0 3 3 3 0 Enolase, N-terminal domain DUF2183 PF09949.9 RKO96808.1 - 6e-23 81.1 0.0 1.6e-22 79.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DUF3543 PF12063.8 RKO96811.1 - 2.8e-15 56.4 0.1 7e-15 55.1 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) DUF2231 PF09990.9 RKO96811.1 - 0.022 15.2 0.0 0.039 14.4 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) SUIM_assoc PF16619.5 RKO96811.1 - 0.046 13.8 4.7 0.13 12.4 4.7 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 tRNA_NucTran2_2 PF13735.6 RKO96811.1 - 0.067 13.2 0.5 0.1 12.6 0.5 1.4 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Catalase_C PF18011.1 RKO96811.1 - 0.072 12.7 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 C-terminal domain found in long catalases Lgl_C PF08596.10 RKO96812.1 - 0.0071 15.1 0.0 0.031 13.0 0.0 1.8 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.32 RKO96812.1 - 0.0084 16.9 1.7 1.8 9.5 0.2 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat BBS2_Mid PF14783.6 RKO96812.1 - 0.039 14.0 0.0 3.3 7.8 0.0 2.5 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 RKO96812.1 - 0.15 12.4 0.1 3.9 7.9 0.0 2.6 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain E1_dh PF00676.20 RKO96813.1 - 2.1e-96 322.4 0.3 2.5e-96 322.2 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RKO96813.1 - 0.0013 18.1 0.0 0.0049 16.1 0.0 1.9 3 0 0 3 3 3 1 1-deoxy-D-xylulose-5-phosphate synthase DEAD PF00270.29 RKO96814.1 - 4.3e-15 55.9 0.0 5.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RKO96814.1 - 0.00025 21.1 0.0 0.00032 20.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 RKO96814.1 - 0.11 11.9 0.8 0.2 11.1 0.8 1.6 1 1 0 1 1 1 0 PhoH-like protein AdoHcyase PF05221.17 RKO96815.1 - 1.1e-137 458.2 0.0 1.1e-75 254.5 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 RKO96815.1 - 1.1e-87 292.2 3.5 1.8e-87 291.5 3.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 RKO96815.1 - 7.8e-10 38.4 0.3 1.8e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 RKO96815.1 - 8.8e-06 25.4 0.2 1.8e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain THF_DHG_CYH_C PF02882.19 RKO96815.1 - 0.012 14.9 1.6 0.04 13.2 1.6 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 RKO96815.1 - 0.019 15.2 0.2 0.046 14.0 0.2 1.7 1 0 0 1 1 1 0 TrkA-N domain DEAD PF00270.29 RKO96817.1 - 2.6e-18 66.4 0.1 2.9e-18 66.2 0.1 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 RKO96817.1 - 0.14 12.1 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PPR_2 PF13041.6 RKO96818.1 - 0.1 12.8 0.1 23 5.2 0.0 3.9 5 0 0 5 5 5 0 PPR repeat family ASH PF15780.5 RKO96819.1 - 1.6e-36 124.4 11.7 0.0012 19.1 0.0 11.7 11 1 0 11 11 11 9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RKO96819.1 - 3.9e-09 36.3 0.0 0.61 10.0 0.0 6.6 7 0 0 7 7 7 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 RKO96819.1 - 1.4e-08 34.7 0.0 5.4 7.1 0.0 7.2 7 0 0 7 7 7 1 Protein of unknown function (DUF1573) PapD-like PF14874.6 RKO96819.1 - 9.6e-08 32.1 0.1 0.044 13.9 0.0 4.9 5 0 0 5 5 5 2 Flagellar-associated PapD-like fn3_5 PF06280.12 RKO96819.1 - 3.3e-07 31.0 8.8 4.7 7.9 0.0 8.1 8 1 0 8 8 7 1 Fn3-like domain MYCBPAP PF14646.6 RKO96819.1 - 0.00039 19.5 0.0 10 4.9 0.0 4.0 4 0 0 4 4 4 1 MYCBP-associated protein family Fn3-like PF14310.6 RKO96819.1 - 0.00043 20.3 0.5 1.2 9.3 0.0 3.9 4 0 0 4 4 4 1 Fibronectin type III-like domain Big_2 PF02368.18 RKO96819.1 - 0.0006 19.7 0.1 2.5 8.1 0.0 4.2 3 0 0 3 3 3 1 Bacterial Ig-like domain (group 2) FixG_C PF11614.8 RKO96819.1 - 0.00085 19.5 0.0 3.8 7.8 0.0 3.8 3 0 0 3 3 3 2 IG-like fold at C-terminal of FixG, putative oxidoreductase LEA_2 PF03168.13 RKO96819.1 - 0.0065 17.0 0.3 0.23 12.0 0.0 3.7 3 0 0 3 3 3 1 Late embryogenesis abundant protein TMEM131_like PF12371.8 RKO96819.1 - 0.014 15.6 13.5 13 6.1 0.0 7.9 10 0 0 10 10 10 0 Transmembrane protein 131-like N_BRCA1_IG PF16158.5 RKO96819.1 - 0.019 15.7 0.0 11 6.8 0.0 4.4 5 0 0 5 5 5 0 Ig-like domain from next to BRCA1 gene Ig_GlcNase PF18368.1 RKO96819.1 - 0.058 13.6 1.0 5 7.3 0.0 4.6 6 1 1 7 7 5 0 Exo-beta-D-glucosaminidase Ig-fold domain FAD_binding_2 PF00890.24 RKO96820.1 - 3.8e-124 414.9 3.4 5e-124 414.6 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 RKO96820.1 - 2.8e-43 146.9 3.9 4.4e-43 146.3 3.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 RKO96820.1 - 1.8e-05 24.1 1.3 0.035 13.2 2.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 RKO96820.1 - 0.00094 18.5 0.6 0.26 10.5 0.1 2.4 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 RKO96820.1 - 0.00097 18.5 0.7 0.0028 17.0 0.1 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RKO96820.1 - 0.0026 17.1 0.2 0.005 16.1 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 RKO96820.1 - 0.035 13.7 0.8 0.07 12.7 0.8 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 RKO96820.1 - 0.37 9.4 1.3 1.3 7.6 0.7 2.2 3 0 0 3 3 3 0 HI0933-like protein SNARE PF05739.19 RKO96821.1 - 2.4e-11 43.4 0.9 4.4e-11 42.6 0.2 1.7 2 0 0 2 2 2 1 SNARE domain Tup_N PF08581.10 RKO96821.1 - 0.057 13.7 0.6 1.1 9.6 0.3 2.7 2 0 0 2 2 2 0 Tup N-terminal Syntaxin-5_N PF11416.8 RKO96821.1 - 0.18 11.1 2.6 0.38 10.0 0.3 2.7 2 0 0 2 2 2 0 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 RKO96821.1 - 1 9.0 4.6 5.8 6.5 0.1 3.2 2 1 0 3 3 3 0 Syntaxin BLOC1_2 PF10046.9 RKO96821.1 - 1.1 9.7 4.5 5 7.5 0.1 3.0 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 RKO96821.1 - 2.5 8.2 7.0 9.3 6.3 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Mnd1 PF03962.15 RKO96822.1 - 5.2e-29 100.3 0.9 1.1e-28 99.2 0.2 1.9 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 RKO96822.1 - 2e-18 66.2 3.2 6.9e-18 64.5 0.5 2.7 1 1 1 2 2 2 1 Leucine zipper with capping helix domain Leu_zip PF15294.6 RKO96822.1 - 0.0018 17.8 3.3 0.003 17.1 3.3 1.3 1 0 0 1 1 1 1 Leucine zipper FlxA PF14282.6 RKO96822.1 - 0.014 15.4 3.5 0.023 14.7 3.5 1.3 1 0 0 1 1 1 0 FlxA-like protein FapA PF03961.13 RKO96822.1 - 0.017 13.7 0.7 0.019 13.6 0.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Penicillinase_R PF03965.16 RKO96822.1 - 0.023 15.0 0.2 0.045 14.1 0.1 1.5 1 1 0 1 1 1 0 Penicillinase repressor Laminin_II PF06009.12 RKO96822.1 - 0.028 14.4 3.1 0.045 13.8 3.1 1.4 1 0 0 1 1 1 0 Laminin Domain II GntR PF00392.21 RKO96822.1 - 0.037 13.7 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family SMK-1 PF04802.15 RKO96822.1 - 0.053 13.4 0.2 0.29 10.9 0.0 1.8 1 1 0 2 2 2 0 Component of IIS longevity pathway SMK-1 Atg14 PF10186.9 RKO96822.1 - 0.09 11.8 3.4 0.12 11.4 3.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5457 PF17540.2 RKO96822.1 - 0.1 12.7 1.2 0.2 11.8 0.1 2.1 2 1 0 2 2 2 0 Family of unknown function (DUF5457) DUF1640 PF07798.11 RKO96822.1 - 0.12 12.5 4.8 0.18 11.9 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TBPIP PF07106.13 RKO96822.1 - 0.13 12.2 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 TBPIP/Hop2 winged helix domain DUF1690 PF07956.11 RKO96822.1 - 0.14 12.5 7.3 0.31 11.5 7.3 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF2203 PF09969.9 RKO96822.1 - 0.16 12.7 1.7 0.32 11.7 1.7 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF724 PF05266.14 RKO96822.1 - 0.22 11.4 5.6 0.39 10.5 5.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMPIT PF07851.13 RKO96822.1 - 0.49 9.6 4.1 0.22 10.7 2.2 1.4 2 0 0 2 2 2 0 TMPIT-like protein CENP-H PF05837.12 RKO96822.1 - 0.54 10.7 7.1 1.1 9.7 7.1 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Phage_GP20 PF06810.11 RKO96822.1 - 1.6 8.6 10.8 1.7 8.4 0.5 2.4 2 1 1 3 3 2 0 Phage minor structural protein GP20 DUF4140 PF13600.6 RKO96822.1 - 2.9 8.4 8.6 5.2 7.6 0.8 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 RKO96822.1 - 3.5 7.5 8.9 1 9.2 0.6 2.5 1 1 1 2 2 2 0 Septum formation initiator FIVAR PF07554.13 RKO96822.1 - 5.2 7.9 7.7 0.67 10.8 2.9 2.0 3 0 0 3 3 1 0 FIVAR domain COPIIcoated_ERV PF07970.12 RKO96823.1 - 1.3e-40 139.6 0.5 1.9e-40 139.0 0.5 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RKO96823.1 - 1.6e-19 70.1 0.7 5.3e-19 68.4 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) ThiF PF00899.21 RKO96824.1 - 2.5e-41 141.6 0.2 3.6e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 RKO96824.1 - 0.00055 20.2 4.6 0.00082 19.6 2.7 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 RKO96824.1 - 0.0013 18.0 0.3 0.0023 17.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 RKO96824.1 - 0.011 16.0 0.1 0.034 14.4 0.1 1.8 1 0 0 1 1 1 0 TrkA-N domain GST_N_2 PF13409.6 RKO96824.1 - 0.018 15.3 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ApbA PF02558.16 RKO96824.1 - 0.025 14.2 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.23 RKO96824.1 - 0.026 14.6 0.1 0.047 13.8 0.1 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 RKO96824.1 - 0.035 13.4 0.5 0.057 12.7 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 RKO96824.1 - 0.048 13.2 0.3 0.095 12.3 0.3 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 RKO96824.1 - 0.058 13.0 0.2 0.097 12.2 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.20 RKO96824.1 - 0.059 13.4 0.5 0.37 10.8 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AA_kinase PF00696.28 RKO96824.1 - 0.092 12.3 0.2 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 Amino acid kinase family 3HCDH_N PF02737.18 RKO96824.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 RKO96824.1 - 0.19 10.8 0.5 0.26 10.3 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A EF-hand_7 PF13499.6 RKO96825.1 - 3.9e-09 36.8 1.2 0.12 12.8 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 RKO96825.1 - 2.3e-07 30.2 0.9 0.089 12.8 0.0 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 RKO96825.1 - 0.00014 21.2 0.0 0.75 9.5 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_13 PF17958.1 RKO96825.1 - 0.028 14.2 0.1 0.68 9.8 0.1 3.1 3 1 1 4 4 4 0 EF-hand domain EF-hand_5 PF13202.6 RKO96825.1 - 0.098 12.2 0.0 0.73 9.4 0.0 2.5 3 0 0 3 3 3 0 EF hand Ldh_1_N PF00056.23 RKO96826.1 - 2.5e-40 137.8 0.4 2.8e-40 137.7 0.4 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 RKO96826.1 - 0.024 13.7 0.0 0.026 13.5 0.0 1.0 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-AN1 PF01428.16 RKO96829.1 - 4.3e-13 49.2 2.1 7e-13 48.5 2.1 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger MMM1 PF10296.9 RKO96830.1 - 0.0013 17.8 0.0 0.063 12.3 0.0 2.7 2 1 1 3 3 3 2 Maintenance of mitochondrial morphology protein 1 PNGaseA PF12222.8 RKO96831.1 - 8e-60 202.9 0.2 1.3e-32 113.2 0.0 2.3 2 1 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A RabGAP-TBC PF00566.18 RKO96832.1 - 2.2e-08 34.0 0.3 0.0062 16.2 0.0 3.1 3 0 0 3 3 3 3 Rab-GTPase-TBC domain KAP PF05804.12 RKO96833.1 - 5.7e-102 342.1 0.6 1.5e-101 340.8 0.6 1.7 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Sugar_tr PF00083.24 RKO96834.1 - 4e-90 302.8 21.7 1.6e-87 294.2 21.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RKO96834.1 - 2.1e-27 96.0 36.0 3e-26 92.2 27.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 RKO96834.1 - 0.00021 19.8 5.2 0.00046 18.7 5.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2830 PF11125.8 RKO96834.1 - 0.15 12.0 0.8 0.37 10.8 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) zf-CCHC PF00098.23 RKO96835.1 - 6.3e-07 29.2 1.3 6.3e-07 29.2 1.3 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_6 PF15288.6 RKO96835.1 - 0.045 13.6 4.8 0.045 13.6 4.8 1.8 2 0 0 2 2 2 0 Zinc knuckle HscB_4_cys PF18256.1 RKO96835.1 - 0.054 13.3 4.6 0.15 11.9 4.6 1.8 1 1 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif Spt20 PF12090.8 RKO96837.1 - 0.0017 18.0 7.7 0.0029 17.2 7.7 1.4 1 0 0 1 1 1 1 Spt20 family UPF0492 PF15744.5 RKO96837.1 - 0.013 14.7 9.5 0.023 13.9 9.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 DUF5349 PF17298.2 RKO96837.1 - 0.029 14.2 2.0 0.056 13.2 2.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Hydin_ADK PF17213.3 RKO96837.1 - 3.3 7.9 7.0 0.69 10.2 2.8 2.2 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Suf PF05843.14 RKO96837.1 - 3.4 7.6 9.9 2.4 8.1 7.5 1.9 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) ISG65-75 PF11727.8 RKO96838.1 - 1 8.5 5.6 2.1 7.5 5.6 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Dynein_light PF01221.18 RKO96839.1 - 4.9e-23 81.3 0.0 5.4e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RGS PF00615.19 RKO96842.1 - 0.017 15.4 0.3 0.034 14.4 0.3 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain Acyl-CoA_dh_1 PF00441.24 RKO96843.1 - 2.4e-31 108.9 0.7 3.7e-31 108.3 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RKO96843.1 - 8.6e-18 64.3 0.1 1.4e-17 63.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RKO96843.1 - 5.8e-10 39.6 0.2 1e-09 38.7 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RKO96843.1 - 0.00013 22.6 0.0 0.00031 21.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain LRR_6 PF13516.6 RKO96844.1 - 1.1e-08 34.4 2.7 0.0096 15.9 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich repeat Endonuc-BsobI PF09194.10 RKO96844.1 - 0.022 14.0 0.8 0.026 13.7 0.1 1.4 2 0 0 2 2 2 0 Restriction endonuclease BsobI Tom7 PF08038.12 RKO96845.1 - 2.6e-15 55.8 0.1 2.9e-15 55.6 0.1 1.0 1 0 0 1 1 1 1 TOM7 family DNAPolymera_Pol PF11590.8 RKO96845.1 - 0.22 11.5 0.8 0.78 9.7 0.0 1.9 1 1 1 2 2 2 0 DNA polymerase catalytic subunit Pol TRAM_LAG1_CLN8 PF03798.16 RKO96846.1 - 2e-17 63.6 21.3 2.7e-17 63.1 21.3 1.2 1 0 0 1 1 1 1 TLC domain ParBc PF02195.18 RKO96847.1 - 0.00025 21.3 0.0 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 ParB-like nuclease domain DUF1015 PF06245.11 RKO96847.1 - 0.12 11.2 0.0 0.2 10.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1015) Tr-sialidase_C PF11052.8 RKO96847.1 - 0.36 11.0 7.5 0.8 9.9 7.5 1.6 1 0 0 1 1 1 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal Arfaptin PF06456.13 RKO96849.1 - 1.1e-19 70.9 7.1 2.3e-19 69.9 7.1 1.4 1 1 0 1 1 1 1 Arfaptin-like domain BRE1 PF08647.11 RKO96849.1 - 8 6.6 9.5 0.2 11.8 1.4 2.4 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Thymidylat_synt PF00303.19 RKO96850.1 - 1.5e-100 335.7 0.0 1.9e-100 335.4 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase Cpn60_TCP1 PF00118.24 RKO96851.1 - 1.7e-150 501.9 3.2 1.9e-150 501.8 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ETF_QO PF05187.13 RKO96853.1 - 4.1e-43 145.8 0.0 7.4e-43 144.9 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 RKO96853.1 - 2.2e-08 33.6 0.6 0.0002 20.6 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 RKO96853.1 - 2.7e-06 27.2 0.0 0.0005 19.8 0.0 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 RKO96853.1 - 8.6e-06 25.2 0.0 0.0003 20.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 RKO96853.1 - 1.8e-05 24.9 0.0 5.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 RKO96853.1 - 8.2e-05 22.0 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RKO96853.1 - 0.0004 19.2 0.6 0.00066 18.5 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 RKO96853.1 - 0.00043 20.3 0.4 0.00099 19.1 0.2 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 RKO96853.1 - 0.0012 18.1 0.2 0.003 16.8 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Fer4_7 PF12838.7 RKO96853.1 - 0.0014 19.2 1.0 0.0032 18.0 1.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox_3 PF13738.6 RKO96853.1 - 0.0022 17.3 0.9 0.0032 16.8 0.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 RKO96853.1 - 0.0026 16.9 0.4 0.0042 16.2 0.4 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 RKO96853.1 - 0.0029 18.1 0.1 1.6 9.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 RKO96853.1 - 0.065 12.6 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fer4_10 PF13237.6 RKO96853.1 - 0.16 12.1 0.9 0.36 11.0 0.9 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 RKO96853.1 - 0.25 10.4 0.4 0.39 9.8 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2080 PF09853.9 RKO96854.1 - 0.029 14.1 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) hemP PF10636.9 RKO96854.1 - 0.22 11.4 2.3 8.5 6.3 0.1 2.4 2 1 0 2 2 2 0 Hemin uptake protein hemP LsmAD PF06741.13 RKO96856.1 - 4.3e-25 88.0 4.3 7.4e-25 87.3 4.3 1.4 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 RKO96856.1 - 6.5e-20 71.1 0.0 1.1e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Carn_acyltransf PF00755.20 RKO96857.1 - 1.3e-126 423.7 0.0 1.4e-126 423.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyltransferase PF01553.21 RKO96858.1 - 2.6e-23 82.1 0.0 3.8e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 RKO96858.1 - 4.3e-10 39.5 0.0 7.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus HMG_CoA_synt_N PF01154.17 RKO96859.1 - 1.2e-80 269.5 0.0 1.6e-80 269.1 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 RKO96859.1 - 4.1e-71 239.9 0.0 5.6e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal adh_short PF00106.25 RKO96860.1 - 1.8e-22 79.8 0.3 2e-22 79.6 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO96860.1 - 1.1e-13 51.3 0.7 1.3e-13 51.1 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKO96860.1 - 1.9e-11 44.2 1.0 2.7e-11 43.7 1.0 1.2 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RKO96860.1 - 5.2e-06 26.1 0.3 6.2e-06 25.8 0.3 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 RKO96860.1 - 0.019 14.9 1.1 0.022 14.6 1.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 RKO96860.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) TFIIS_C PF01096.18 RKO96862.1 - 7.2e-13 48.1 8.5 8.7e-12 44.7 2.0 2.4 3 0 0 3 3 3 2 Transcription factor S-II (TFIIS) Ogr_Delta PF04606.12 RKO96862.1 - 2.6e-05 24.1 3.6 0.0012 18.8 1.0 2.3 2 0 0 2 2 2 2 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 RKO96862.1 - 0.0027 18.0 1.0 0.0099 16.2 0.3 1.9 2 0 0 2 2 2 1 Restriction alleviation protein Lar CpXC PF14353.6 RKO96862.1 - 0.018 15.1 1.6 0.7 9.9 0.1 2.2 2 0 0 2 2 2 0 CpXC protein Zn_Tnp_IS1595 PF12760.7 RKO96862.1 - 0.018 15.0 5.2 0.21 11.6 1.8 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain TniQ PF06527.11 RKO96862.1 - 0.033 14.9 0.6 0.037 14.8 0.6 1.1 1 0 0 1 1 1 0 TniQ Zn-ribbon_8 PF09723.10 RKO96862.1 - 0.038 14.1 2.2 9 6.5 0.0 3.1 3 0 0 3 3 3 0 Zinc ribbon domain RNA_POL_M_15KD PF02150.16 RKO96862.1 - 0.043 13.7 0.2 0.043 13.7 0.2 2.6 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit DUF4892 PF16234.5 RKO96862.1 - 0.18 11.3 0.7 1.4 8.4 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4892) UPF0547 PF10571.9 RKO96862.1 - 9.4 6.4 9.8 12 6.1 0.7 2.8 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 YjeF_N PF03853.15 RKO96864.1 - 1.1e-25 90.5 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF3756 PF12581.8 RKO96866.1 - 0.011 15.6 0.6 0.035 14.0 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3756) LPD26 PF18842.1 RKO96866.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein associated domain 26 zf-RING_4 PF14570.6 RKO96867.1 - 1.1e-20 73.1 13.8 1.1e-20 73.1 13.8 1.7 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 RKO96867.1 - 1.5e-05 24.7 0.3 0.00022 21.0 0.3 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 RKO96867.1 - 2.1e-05 24.3 10.2 4.8e-05 23.1 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO96867.1 - 9.5e-05 22.7 11.5 9.5e-05 22.7 11.5 1.9 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 RKO96867.1 - 0.00013 21.8 9.1 0.0075 16.1 5.7 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-UDP PF14569.6 RKO96867.1 - 0.0044 17.1 8.4 0.0059 16.7 5.2 2.3 2 0 0 2 2 2 1 Zinc-binding RING-finger Nup35_RRM PF05172.13 RKO96867.1 - 0.007 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Baculo_IE-1 PF05290.11 RKO96867.1 - 0.008 16.1 8.8 0.012 15.5 7.8 1.8 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Torus PF16131.5 RKO96867.1 - 0.0082 16.8 3.3 0.011 16.4 0.1 2.2 2 0 0 2 2 2 1 Torus domain Nup35_RRM_2 PF14605.6 RKO96867.1 - 0.027 14.5 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-Di19 PF05605.12 RKO96867.1 - 0.22 11.8 4.0 1.8 8.9 1.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_UBOX PF13445.6 RKO96867.1 - 2.5 8.2 10.9 2.7 8.1 6.2 2.3 2 0 0 2 2 2 0 RING-type zinc-finger DNA_pol_E_B PF04042.16 RKO96868.1 - 1.6e-40 138.7 1.1 2.2e-40 138.3 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Phage_TAC_11 PF11836.8 RKO96868.1 - 0.17 12.0 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 Phage tail tube protein, GTA-gp10 VWA_2 PF13519.6 RKO96869.1 - 0.0055 17.3 0.0 0.0094 16.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain PatG_D PF18047.1 RKO96869.1 - 0.016 15.7 0.0 0.058 13.8 0.0 1.7 1 1 1 2 2 2 0 PatG Domain Ribosomal_L31e PF01198.19 RKO96870.1 - 3.2e-31 107.4 1.3 4e-31 107.1 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e TPR_1 PF00515.28 RKO96872.1 - 5.9e-13 48.0 0.6 0.0016 18.1 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 RKO96872.1 - 1.4e-11 43.5 2.6 0.0018 18.3 0.2 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 RKO96872.1 - 1.8e-07 30.8 0.4 2.5e-05 23.9 0.2 2.7 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 RKO96872.1 - 2e-05 25.1 1.8 6.4e-05 23.5 1.0 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKO96872.1 - 4.9e-05 23.1 0.3 0.0021 18.0 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKO96872.1 - 0.00012 22.3 6.1 0.009 16.3 0.9 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKO96872.1 - 0.0015 19.0 2.0 0.26 11.8 0.2 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKO96872.1 - 0.0025 18.5 3.7 0.077 13.9 0.2 3.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 RKO96872.1 - 0.0058 16.5 0.6 0.023 14.6 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 RKO96872.1 - 0.012 15.7 0.5 0.012 15.7 0.5 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKO96872.1 - 0.055 14.1 2.5 4.5 8.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKO96872.1 - 0.077 13.4 2.0 32 5.2 0.0 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO96872.1 - 0.12 12.6 1.9 4.9 7.4 0.9 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RRM_1 PF00076.22 RKO96874.1 - 1.1e-18 66.8 0.0 1.6e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKO96874.1 - 0.0038 17.1 0.0 0.0081 16.0 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 RKO96874.1 - 0.012 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDUF_B4 PF07225.12 RKO96875.1 - 8.8e-06 25.6 0.0 9.8e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Ribosomal_L16 PF00252.18 RKO96876.1 - 4.3e-35 120.6 0.1 4.6e-35 120.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e AAA_12 PF13087.6 RKO96877.1 - 2.4e-40 138.3 0.0 3.8e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RKO96877.1 - 2e-27 96.6 0.0 4.2e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO96877.1 - 2.8e-10 40.7 0.0 5.9e-09 36.4 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.6 RKO96877.1 - 2.7e-08 33.8 0.1 0.0004 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 RKO96877.1 - 2.1e-05 24.2 0.0 5e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 RKO96877.1 - 0.0012 18.2 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.6 RKO96877.1 - 0.0083 15.9 0.1 0.045 13.6 0.0 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 RKO96877.1 - 0.02 15.3 0.1 0.089 13.2 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 RKO96877.1 - 0.051 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 RKO96877.1 - 0.065 13.5 0.0 0.4 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 RKO96877.1 - 0.08 13.4 0.0 0.47 10.9 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DNA_binding_1 PF01035.20 RKO96880.1 - 1.5e-21 76.3 0.4 1.8e-21 76.0 0.4 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Hexokinase_2 PF03727.16 RKO96881.1 - 2.9e-83 279.0 0.0 3.8e-83 278.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RKO96881.1 - 8.4e-67 224.9 0.1 1.8e-66 223.9 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Ribosomal_S28e PF01200.18 RKO96884.1 - 1.1e-29 102.2 3.8 1.3e-29 102.0 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Imm49 PF15575.6 RKO96886.1 - 0.045 13.5 0.2 0.061 13.1 0.2 1.1 1 0 0 1 1 1 0 Immunity protein 49 Nop14 PF04147.12 RKO96887.1 - 0.27 9.4 15.9 0.34 9.1 15.9 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 RKO96887.1 - 0.58 9.5 16.7 0.72 9.2 16.7 1.3 1 0 0 1 1 1 0 SDA1 UDPGP PF01704.18 RKO96888.1 - 7.9e-179 594.6 0.0 1e-178 594.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase ORC_WH_C PF18137.1 RKO96889.1 - 1.4e-28 99.7 0.3 3.3e-15 56.4 0.0 2.1 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal FA_desaturase PF00487.24 RKO96890.1 - 1.1e-36 126.9 23.6 2e-36 126.1 23.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 RKO96890.1 - 2.4e-12 46.8 0.0 5.6e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nrap_D4 PF17405.2 RKO96893.1 - 2.3e-26 92.5 0.3 9.4e-26 90.5 0.1 1.9 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 RKO96893.1 - 1.2e-21 77.2 0.0 2.2e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 RKO96893.1 - 5e-20 71.8 0.0 3.2e-18 65.9 0.0 2.4 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D6 PF17407.2 RKO96893.1 - 3.9e-16 59.5 0.0 6.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Nrap protein domain 6 Nrap PF03813.14 RKO96893.1 - 2.7e-14 53.5 0.1 9.1e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 RKO96893.1 - 4.2e-11 43.2 0.0 1e-10 41.9 0.0 1.6 1 0 0 1 1 1 1 Nrap protein domain 3 Ras PF00071.22 RKO96894.1 - 1.2e-17 64.0 0.0 1.8e-17 63.4 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 RKO96894.1 - 1.5e-10 41.4 0.0 3.5e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 RKO96894.1 - 0.032 14.2 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.6 RKO96894.1 - 0.069 13.5 0.2 0.1 13.0 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 RKO96894.1 - 0.089 12.7 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 RKO96894.1 - 0.1 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 RKO96894.1 - 0.14 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Choline_transpo PF04515.12 RKO96895.1 - 5.3e-05 22.6 1.8 5.3e-05 22.6 1.8 1.9 3 0 0 3 3 3 1 Plasma-membrane choline transporter Pkinase PF00069.25 RKO96896.1 - 7.6e-49 166.4 0.0 1e-48 166.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96896.1 - 6.1e-40 137.1 0.0 7.5e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 RKO96896.1 - 0.012 15.0 0.2 0.019 14.3 0.2 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKO96896.1 - 0.024 14.0 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 RKO96896.1 - 0.032 13.0 0.0 0.051 12.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Acyl-CoA_dh_1 PF00441.24 RKO96897.1 - 7e-40 136.7 0.1 9.1e-40 136.3 0.1 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 RKO96897.1 - 1.8e-16 60.1 0.0 3.2e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RKO96897.1 - 3.6e-14 53.2 0.2 4.9e-14 52.8 0.2 1.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AAA PF00004.29 RKO96898.1 - 8e-06 26.3 0.0 2e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 RKO96898.1 - 0.007 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 RKO96898.1 - 0.014 15.7 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 RKO96898.1 - 0.022 14.9 0.1 0.095 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 RKO96898.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 RKO96898.1 - 0.05 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4551 PF15087.6 RKO96900.1 - 2.2 7.0 9.1 2.4 6.9 9.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CytochromB561_N PF09786.9 RKO96900.1 - 2.8 6.8 7.6 3 6.7 7.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SRP-alpha_N PF04086.13 RKO96900.1 - 5.1 6.9 13.2 6.6 6.6 13.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BolA PF01722.18 RKO96901.1 - 3.3e-16 59.3 0.0 8.3e-16 58.0 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein Diphthami_syn_2 PF01902.17 RKO96903.1 - 1.9e-35 122.3 0.0 6.8e-26 91.1 0.0 2.0 2 0 0 2 2 2 2 Diphthamide synthase SET PF00856.28 RKO96904.1 - 5.7e-22 78.9 0.8 1e-20 74.8 0.8 2.1 1 1 0 1 1 1 1 SET domain WD40 PF00400.32 RKO96905.1 - 2e-19 69.6 0.2 4.5e-09 36.8 0.0 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO96905.1 - 3.9e-10 39.9 0.2 4.9e-06 26.7 0.0 3.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO96905.1 - 0.0021 16.8 0.0 0.0039 15.9 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RKO96905.1 - 0.019 13.7 0.0 1.4 7.5 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like DUF4920 PF16267.5 RKO96905.1 - 0.032 14.2 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4920) WD40_like PF17005.5 RKO96905.1 - 0.044 13.1 0.0 0.063 12.6 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain Frtz PF11768.8 RKO96905.1 - 0.062 11.6 0.0 0.11 10.8 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 RKO96905.1 - 0.087 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome D1 heme domain Med23 PF11573.8 RKO96905.1 - 0.15 9.7 0.0 0.18 9.4 0.0 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 TALPID3 PF15324.6 RKO96906.1 - 0.65 7.6 2.6 0.95 7.1 2.6 1.1 1 0 0 1 1 1 0 Hedgehog signalling target ETC_C1_NDUFA5 PF04716.14 RKO96907.1 - 2.7e-18 65.5 0.1 4.3e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region COG7 PF10191.9 RKO96907.1 - 0.032 12.5 0.2 0.05 11.8 0.2 1.3 1 1 0 1 1 1 0 Golgi complex component 7 (COG7) VWA_2 PF13519.6 RKO96907.1 - 0.12 13.1 0.0 0.32 11.7 0.0 1.7 1 1 1 2 2 2 0 von Willebrand factor type A domain RGS PF00615.19 RKO96909.1 - 1.1e-07 32.2 0.0 2.4e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain GATA-N PF05349.12 RKO96909.1 - 0.058 13.7 2.0 0.13 12.6 0.5 2.1 2 0 0 2 2 2 0 GATA-type transcription activator, N-terminal UPF0492 PF15744.5 RKO96909.1 - 0.19 10.9 0.0 0.99 8.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein family UPF0492 AzlD PF05437.12 RKO96909.1 - 2.5 8.3 14.9 0.56 10.4 0.3 3.4 4 0 0 4 4 4 0 Branched-chain amino acid transport protein (AzlD) Nramp PF01566.18 RKO96910.1 - 1.9e-101 339.6 26.9 5.9e-101 338.0 26.9 1.6 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein LRR19-TM PF15176.6 RKO96910.1 - 0.036 14.1 1.2 3.6 7.6 0.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeat family 19 TM domain Prp19 PF08606.11 RKO96911.1 - 9.3e-30 102.4 2.4 1.4e-29 101.9 2.4 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.8 RKO96911.1 - 0.0092 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 RKO96911.1 - 0.0098 15.3 0.0 0.018 14.4 0.0 1.4 2 0 0 2 2 2 1 Rtf2 RING-finger AMP-binding PF00501.28 RKO96912.1 - 1.9e-93 313.4 0.1 2.7e-93 312.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RNA_pol_Rpb1_5 PF04998.17 RKO96912.1 - 0.13 11.7 0.0 0.31 10.4 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 URO-D PF01208.17 RKO96913.1 - 6.5e-129 430.0 0.0 7.3e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Sulfate_transp PF00916.20 RKO96914.1 - 1.2e-78 264.5 16.0 1.6e-78 264.1 16.0 1.1 1 0 0 1 1 1 1 Sulfate permease family AAA_lid_10 PF17872.1 RKO96918.1 - 0.032 14.4 0.0 0.061 13.4 0.0 1.4 1 1 0 1 1 1 0 AAA lid domain AAA PF00004.29 RKO96918.1 - 0.047 14.1 0.0 0.075 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FKBP_C PF00254.28 RKO96919.1 - 0.0018 18.6 0.0 0.0029 17.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase S4 PF01479.25 RKO96920.1 - 2.6e-10 39.8 0.1 4.1e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 RKO96920.1 - 0.059 13.2 0.0 0.09 12.6 0.0 1.2 1 0 0 1 1 1 0 S4 domain CotE PF10628.9 RKO96921.1 - 0.027 14.1 3.3 0.048 13.3 3.3 1.3 1 0 0 1 1 1 0 Outer spore coat protein E (CotE) Methyltransf_25 PF13649.6 RKO96921.1 - 0.39 11.5 1.3 24 5.7 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain HSP20 PF00011.21 RKO96922.1 - 1.1e-10 41.5 0.3 4.3e-06 26.8 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family DUF3841 PF12952.7 RKO96922.1 - 0.025 14.4 0.2 0.036 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) zf-RING_2 PF13639.6 RKO96923.1 - 1.1e-08 35.2 2.1 2e-08 34.4 2.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 RKO96923.1 - 1.6e-06 27.8 1.5 2.9e-06 27.0 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO96923.1 - 3.6e-06 26.9 0.5 7.4e-06 25.9 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 RKO96923.1 - 9.3e-06 25.8 3.3 4.4e-05 23.7 3.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKO96923.1 - 0.0012 18.8 1.8 0.0021 18.0 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 RKO96923.1 - 0.0015 18.3 2.3 0.0042 16.9 2.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKO96923.1 - 0.0048 17.0 1.7 0.0058 16.8 0.1 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 RKO96923.1 - 0.0071 16.4 0.6 0.014 15.4 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 RKO96923.1 - 0.0073 16.2 4.4 0.013 15.4 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 RKO96923.1 - 0.0073 16.0 1.1 0.0073 16.0 1.1 2.0 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 RKO96923.1 - 0.066 13.4 2.2 0.16 12.2 2.2 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 RKO96923.1 - 0.29 10.8 3.6 0.61 9.8 3.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type B277 PF17623.2 RKO96923.1 - 0.54 9.3 1.3 1.1 8.3 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function HbrB PF08539.11 RKO96924.1 - 2.4e-21 76.5 0.0 2.7e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 HbrB-like KH_1 PF00013.29 RKO96925.1 - 0.00023 20.9 0.7 0.00044 20.0 0.7 1.5 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 RKO96925.1 - 0.082 13.0 0.0 0.2 11.8 0.0 1.6 2 0 0 2 2 2 0 Krr1 KH1 domain UBA2_C PF16195.5 RKO96925.1 - 0.091 13.5 0.6 0.15 12.7 0.6 1.3 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus BCDHK_Adom3 PF10436.9 RKO96926.1 - 1.1e-36 126.2 0.0 1.9e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 RKO96926.1 - 0.024 15.2 0.0 0.058 13.9 0.0 1.5 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RKO96926.1 - 0.17 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zip PF02535.22 RKO96927.1 - 7.9e-45 153.5 21.6 4.5e-43 147.7 21.6 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3302 PF11742.8 RKO96927.1 - 1.3 9.2 4.5 0.27 11.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) p450 PF00067.22 RKO96928.1 - 3.1e-19 69.1 0.0 3.4e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 RKO96929.1 - 4.1e-22 78.8 0.0 4.8e-22 78.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96929.1 - 1.8e-20 73.4 0.0 2.1e-20 73.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 RKO96929.1 - 0.091 12.3 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 RIO1 family SNARE_assoc PF09335.11 RKO96930.1 - 2.4e-14 53.9 8.4 4.7e-14 52.9 8.4 1.5 1 0 0 1 1 1 1 SNARE associated Golgi protein DUF4567 PF15131.6 RKO96930.1 - 0.089 12.9 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4567) Ribosomal_L7Ae PF01248.26 RKO96931.1 - 8e-18 64.0 1.1 8.5e-13 47.9 0.0 2.3 2 1 0 2 2 2 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 RKO96931.1 - 0.0014 18.7 0.0 0.0017 18.4 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Ferrochelatase PF00762.19 RKO96932.1 - 2e-107 358.9 0.0 2.3e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF4921 PF16268.5 RKO96932.1 - 0.041 12.7 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4921) zf-NADH-PPase PF09297.11 RKO96932.1 - 0.11 12.2 0.7 0.22 11.2 0.7 1.6 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DNA_RNApol_7kD PF03604.13 RKO96933.1 - 5.6e-17 61.1 7.5 8e-17 60.6 7.5 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit MCM_OB PF17207.3 RKO96933.1 - 0.007 16.2 0.6 0.0089 15.9 0.6 1.1 1 0 0 1 1 1 1 MCM OB domain DZR PF12773.7 RKO96933.1 - 0.02 14.9 1.6 0.023 14.7 0.8 1.5 2 0 0 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 RKO96933.1 - 0.067 13.1 2.7 0.53 10.2 0.2 2.5 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_10 PF10058.9 RKO96933.1 - 0.067 12.9 2.2 0.46 10.2 0.2 2.2 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein HypA PF01155.19 RKO96933.1 - 0.08 13.0 0.8 0.098 12.7 0.8 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF951 PF06107.11 RKO96933.1 - 0.11 12.4 1.5 0.16 11.9 1.3 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DUF1451 PF07295.11 RKO96933.1 - 0.14 12.2 0.9 0.17 11.9 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_ribbon_recom PF13408.6 RKO96933.1 - 0.16 12.5 5.8 0.22 12.1 0.6 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 RKO96933.1 - 0.37 11.0 4.5 1.4 9.1 4.4 1.9 1 1 1 2 2 2 0 Zinc ribbon domain zf_UBZ PF18439.1 RKO96933.1 - 0.61 9.7 2.3 13 5.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Rubredoxin_2 PF18073.1 RKO96933.1 - 0.84 9.4 6.0 7.2 6.4 0.8 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-trcl PF13451.6 RKO96933.1 - 1.4 8.9 5.1 7.6 6.5 1.5 2.6 2 1 0 2 2 2 0 Probable zinc-ribbon domain ABC_tran_CTD PF16326.5 RKO96934.1 - 0.0082 16.4 9.6 0.0082 16.4 9.6 6.9 4 2 2 7 7 7 2 ABC transporter C-terminal domain Spc7 PF08317.11 RKO96934.1 - 0.0096 14.8 42.1 0.15 10.9 17.4 3.1 2 1 2 4 4 4 2 Spc7 kinetochore protein ADIP PF11559.8 RKO96934.1 - 0.0097 16.0 9.7 0.0097 16.0 9.7 4.7 2 1 3 5 5 5 2 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 RKO96934.1 - 0.031 11.8 37.7 0.052 11.1 37.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Csm1_N PF18504.1 RKO96934.1 - 0.043 14.1 1.4 0.043 14.1 1.4 6.7 3 2 3 6 6 6 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 RKO96934.1 - 0.069 13.0 33.7 0.51 10.1 7.1 4.1 1 1 3 4 4 4 0 Phage minor structural protein GP20 Bacillus_HBL PF05791.11 RKO96934.1 - 0.35 10.7 11.9 0.12 12.2 0.7 3.2 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MPS2 PF17060.5 RKO96934.1 - 0.51 9.5 17.8 0.17 11.1 1.1 4.0 2 1 0 3 3 3 0 Monopolar spindle protein 2 DUF5082 PF16888.5 RKO96934.1 - 0.63 10.3 18.4 0.45 10.8 3.8 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 RKO96934.1 - 0.64 10.1 18.2 0.48 10.5 0.7 3.9 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 RKO96934.1 - 0.8 9.0 29.1 0.12 11.7 6.2 3.0 1 1 2 3 3 3 0 FAM76 protein Atg14 PF10186.9 RKO96934.1 - 0.92 8.5 33.5 0.069 12.2 12.4 3.0 1 1 2 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 RKO96934.1 - 0.95 9.0 40.1 1.2 8.6 12.4 3.7 2 1 1 3 3 3 0 Intermediate filament protein COMMD1_N PF17221.3 RKO96934.1 - 1.1 9.6 17.2 2 8.8 1.1 4.7 1 1 4 5 5 5 0 COMMD1 N-terminal domain UPF0242 PF06785.11 RKO96934.1 - 2.1 8.4 34.1 1.2 9.2 8.6 3.2 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 RKO96934.1 - 2.3 8.4 66.5 0.73 10.0 13.7 4.1 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Golgin_A5 PF09787.9 RKO96934.1 - 2.4 7.6 41.7 0.33 10.4 11.8 2.9 2 2 1 3 3 3 0 Golgin subfamily A member 5 FlaC_arch PF05377.11 RKO96934.1 - 2.6 8.5 13.5 3.4 8.1 0.4 4.9 3 2 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF713 PF05218.14 RKO96934.1 - 2.7 7.7 6.5 1.6 8.4 0.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF713) Lebercilin PF15619.6 RKO96934.1 - 2.9 7.5 47.3 0.12 12.0 19.8 3.2 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Leu_zip PF15294.6 RKO96934.1 - 3.7 7.0 29.6 0.39 10.2 11.5 3.2 1 1 2 3 3 3 0 Leucine zipper CHDCT2 PF08074.11 RKO96934.1 - 5.2 7.2 25.1 4.5 7.4 4.3 3.6 2 1 0 3 3 3 0 CHDCT2 (NUC038) domain Baculo_PEP_C PF04513.12 RKO96934.1 - 5.3 7.1 30.4 2.1 8.4 1.8 3.8 2 1 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 RKO96934.1 - 6.8 5.2 31.8 0.071 11.8 6.5 2.7 1 1 2 3 3 3 0 AAA domain FapA PF03961.13 RKO96934.1 - 7.9 5.0 16.8 7 5.1 6.2 2.4 1 1 0 2 2 2 0 Flagellar Assembly Protein A Fez1 PF06818.15 RKO96934.1 - 8.7 6.7 41.6 0.45 10.9 18.5 2.7 2 1 1 3 3 3 0 Fez1 DUF16 PF01519.16 RKO96934.1 - 9.3 6.8 14.6 0.79 10.2 1.2 3.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 tRNA-synt_1b PF00579.25 RKO96935.1 - 2.1e-57 194.7 0.0 2.8e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 RKO96935.1 - 1.2e-05 25.1 0.0 2.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Tyrosyl-tRNA synthetase C-terminal domain S4 PF01479.25 RKO96935.1 - 0.0094 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain CX9C PF16860.5 RKO96936.1 - 1.5e-14 53.7 8.3 2.1e-08 34.1 1.1 2.0 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 RKO96936.1 - 3.8e-09 36.5 2.4 0.00096 19.2 0.0 3.1 2 1 1 3 3 3 3 CHCH domain Cmc1 PF08583.10 RKO96936.1 - 1e-08 35.1 6.6 0.00012 22.0 0.6 2.5 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 RKO96936.1 - 3.9e-05 23.9 6.8 0.061 13.7 1.3 3.1 2 1 1 3 3 3 3 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.16 RKO96936.1 - 0.0002 21.5 6.9 0.031 14.5 0.8 2.6 1 1 1 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein TPR_14 PF13428.6 RKO96936.1 - 0.00046 20.8 0.1 0.53 11.2 0.0 3.1 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RKO96936.1 - 0.0034 17.2 0.0 2.5 8.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat MTCP1 PF08991.10 RKO96936.1 - 0.0098 16.1 8.1 0.1 12.8 4.3 2.7 1 1 1 2 2 2 1 Mature-T-Cell Proliferation I type GCK PF07802.11 RKO96936.1 - 0.012 16.0 4.4 2.6 8.5 0.3 2.6 1 1 1 2 2 2 0 GCK domain UPF0203 PF05254.12 RKO96936.1 - 0.015 15.5 4.8 1.6 9.1 3.1 2.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) NDUF_B7 PF05676.13 RKO96936.1 - 0.03 14.0 6.5 0.73 9.6 0.5 2.5 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 RKO96936.1 - 0.033 14.4 7.2 1.1 9.6 2.0 2.7 1 1 2 3 3 3 0 Cytochrome oxidase c subunit VIb APP_E2 PF12925.7 RKO96936.1 - 0.061 13.0 0.0 1.6 8.4 0.0 2.0 1 1 1 2 2 2 0 E2 domain of amyloid precursor protein TPR_2 PF07719.17 RKO96936.1 - 0.08 13.1 0.2 8.2 6.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 RKO96936.1 - 0.095 12.4 0.0 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 TPR repeat Pet191_N PF10203.9 RKO96936.1 - 0.1 12.9 9.4 1.6 9.0 5.6 2.9 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 T-box PF00907.22 RKO96938.1 - 3.1e-45 154.7 0.0 4.5e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 T-box Rib_5-P_isom_A PF06026.14 RKO96940.1 - 1.1e-44 152.1 0.0 2.1e-44 151.2 0.0 1.5 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) NAD_binding_10 PF13460.6 RKO96940.1 - 0.0019 18.1 0.1 0.0033 17.3 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Ribosomal_S19e PF01090.19 RKO96940.1 - 0.12 12.0 0.0 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S19e zf-CCHC PF00098.23 RKO96941.1 - 0.00036 20.5 3.7 0.00055 19.9 3.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 RKO96941.1 - 0.0081 16.0 7.2 0.013 15.3 7.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 RKO96941.1 - 0.012 15.5 0.5 0.022 14.7 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.8 RKO96941.1 - 0.19 12.1 0.1 0.33 11.3 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G AF-4 PF05110.13 RKO96942.1 - 2 6.4 15.2 5.4 5.0 15.2 1.7 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HHH_2 PF12826.7 RKO96943.1 - 0.088 12.9 0.0 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Pkinase PF00069.25 RKO96944.1 - 1.3e-66 224.7 0.0 1.5e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO96944.1 - 4.3e-40 137.6 0.0 5.2e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO96944.1 - 3.4e-05 23.3 0.0 4.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKO96944.1 - 9.3e-05 21.4 0.0 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 RKO96944.1 - 0.0074 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 RKO96944.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD PF00270.29 RKO96945.1 - 1.5e-37 129.0 0.0 2.3e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO96945.1 - 2.8e-20 72.7 0.0 4.7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RKO96945.1 - 5.3e-17 61.8 0.0 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RKO96945.1 - 0.14 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SNF2_N PF00176.23 RKO96945.1 - 0.16 10.7 0.0 0.29 9.8 0.0 1.4 1 1 0 1 1 1 0 SNF2 family N-terminal domain Tyrosinase PF00264.20 RKO96946.1 - 3.5e-15 56.9 0.1 5.6e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box PF00505.19 RKO96946.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box PHD PF00628.29 RKO96947.1 - 2e-08 34.0 4.6 2e-08 34.0 4.6 2.9 4 0 0 4 4 4 1 PHD-finger zf-CpG_bind_C PF12269.8 RKO96947.1 - 0.0083 15.9 0.3 0.018 14.9 0.3 1.5 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain DUF1427 PF07235.11 RKO96948.1 - 0.0023 17.9 0.2 0.0051 16.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1427) RSN1_7TM PF02714.15 RKO96949.1 - 1.2e-21 77.3 1.1 1.3e-21 77.2 1.1 1.0 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate ATP-synt_F PF01990.17 RKO96950.1 - 6e-31 106.6 0.1 6.9e-31 106.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Dynamin_N PF00350.23 RKO96951.1 - 2.2e-42 144.9 0.0 3.4e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 RKO96951.1 - 6.4e-07 28.9 0.0 1.8e-05 24.1 0.0 2.8 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 RKO96951.1 - 1.7e-06 28.1 0.0 4.5e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 RKO96951.1 - 0.013 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 RKO96951.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 RKO96951.1 - 0.11 12.7 1.1 0.27 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 RKO96951.1 - 0.23 11.7 0.0 0.55 10.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 RKO96951.1 - 3.5 8.0 6.2 1.3 9.4 0.0 3.3 3 2 1 4 4 4 0 AAA ATPase domain WD40_4 PF16300.5 RKO96954.1 - 8.2e-07 28.8 0.1 2.3e-06 27.4 0.0 1.9 2 0 0 2 2 2 1 Type of WD40 repeat Nop PF01798.18 RKO96955.1 - 4.6e-72 242.2 0.0 4.6e-72 242.2 0.0 2.4 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 RKO96955.1 - 9.4e-10 38.7 0.1 9.4e-10 38.7 0.1 3.0 2 1 0 2 2 2 1 NOP5NT (NUC127) domain DUF1776 PF08643.10 RKO96955.1 - 0.03 13.7 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) PPL5 PF18168.1 RKO96955.1 - 1.2 8.4 8.9 1.9 7.7 8.9 1.3 1 0 0 1 1 1 0 Prim-pol family 5 DUF913 PF06025.12 RKO96955.1 - 3.1 6.7 8.6 6.5 5.6 8.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FXMRP1_C_core PF12235.8 RKO96955.1 - 6.2 7.5 12.4 9.3 6.9 12.4 1.2 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal NAD_kinase PF01513.21 RKO96956.1 - 1.9e-48 165.1 0.0 3.6e-48 164.3 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DUF1427 PF07235.11 RKO96956.1 - 0.085 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) DAGK_cat PF00781.24 RKO96956.1 - 0.14 11.8 0.4 0.21 11.2 0.4 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain RVT_1 PF00078.27 RKO96957.1 - 1.1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CHORD PF04968.12 RKO96958.1 - 7.4e-51 170.7 12.7 8.5e-28 96.9 3.0 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 RKO96958.1 - 6.6e-15 55.9 0.0 9.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 CS domain tRNA-synt_2b PF00587.25 RKO96959.1 - 2.3e-09 37.5 0.0 4.1e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ADH_zinc_N PF00107.26 RKO96960.1 - 2.5e-16 59.8 0.0 4.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 RKO96960.1 - 0.061 12.7 0.2 0.15 11.4 0.1 1.7 2 1 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme NmrA PF05368.13 RKO96960.1 - 0.15 11.6 0.2 3.6 7.1 0.1 2.4 3 0 0 3 3 3 0 NmrA-like family RCC1 PF00415.18 RKO96961.1 - 1.4e-06 28.8 0.1 0.0072 16.9 0.0 3.8 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKO96961.1 - 0.023 14.5 15.8 1.5 8.7 0.2 4.1 4 0 0 4 4 4 0 Regulator of chromosome condensation (RCC1) repeat DsbD PF02683.15 RKO96963.1 - 0.027 14.4 0.2 0.051 13.5 0.2 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF2464 PF10240.9 RKO96963.1 - 0.21 11.1 0.6 0.43 10.1 0.6 1.4 1 0 0 1 1 1 0 Multivesicular body subunit 12 AhpC-TSA PF00578.21 RKO96964.1 - 1.8e-29 102.2 0.0 2.5e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKO96964.1 - 4.6e-13 49.1 0.0 6.4e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 RKO96964.1 - 4.3e-11 42.5 0.0 8.1e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin tRNA_lig_CPD PF08302.11 RKO96967.1 - 4.6e-05 23.0 0.0 9.5e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.11 RKO96967.1 - 0.00023 21.3 0.0 0.0032 17.6 0.0 2.3 1 1 0 1 1 1 1 tRNA ligase kinase domain AAA_28 PF13521.6 RKO96967.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 RKO96967.1 - 0.069 13.7 0.0 0.26 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain PAP2 PF01569.21 RKO96968.1 - 3.3e-10 39.9 11.6 5e-10 39.3 7.6 2.6 1 1 1 2 2 2 1 PAP2 superfamily DUF1538 PF07556.11 RKO96968.1 - 0.025 13.9 0.3 0.025 13.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) DUF212 PF02681.14 RKO96968.1 - 0.3 11.2 2.5 0.51 10.5 0.3 2.4 1 1 1 2 2 2 0 Divergent PAP2 family DUF2070 PF09843.9 RKO96968.1 - 1.4 7.2 3.5 1.9 6.7 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DoxX_2 PF13564.6 RKO96968.1 - 3.6 7.8 21.0 3.5 7.8 0.0 3.2 1 1 2 3 3 3 0 DoxX-like family DUF1664 PF07889.12 RKO96969.1 - 0.25 11.4 0.1 0.54 10.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Med14 PF08638.11 RKO96970.1 - 1.5e-35 122.3 0.3 2.6e-35 121.6 0.3 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Hemocyanin_M PF00372.19 RKO96970.1 - 0.16 11.1 0.1 0.26 10.4 0.1 1.2 1 0 0 1 1 1 0 Hemocyanin, copper containing domain Ribosomal_L3 PF00297.22 RKO96971.1 - 6.9e-177 588.0 9.1 7.9e-177 587.8 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 tRNA-synt_2d PF01409.20 RKO96972.1 - 1.7e-46 158.7 0.4 2.4e-24 86.2 0.1 2.8 2 1 1 3 3 3 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 RKO96972.1 - 5.7e-22 78.0 0.0 1.1e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain EFG_C PF00679.24 RKO96973.1 - 4.6e-19 68.2 0.0 1.1e-18 67.1 0.0 1.7 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RKO96973.1 - 5.8e-06 26.6 0.1 1.8e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 RKO96973.1 - 4.4e-05 23.1 0.0 9.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Transket_pyr PF02779.24 RKO96974.1 - 1.8e-45 154.8 0.0 3.6e-45 153.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 RKO96974.1 - 6.5e-40 135.9 0.2 2e-39 134.3 0.1 1.9 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 RKO96974.1 - 2.9e-05 24.3 0.0 0.0001 22.6 0.0 1.9 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II adh_short PF00106.25 RKO96975.1 - 1.9e-30 105.8 0.2 6e-30 104.2 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO96975.1 - 1e-16 61.2 1.4 6.8e-16 58.5 1.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 RKO96975.1 - 0.0011 18.9 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 RKO96975.1 - 0.0058 16.6 0.8 0.01 15.8 0.8 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 RKO96975.1 - 0.012 15.0 0.0 0.019 14.5 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 RKO96975.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.15 RKO96975.1 - 0.1 12.5 0.3 0.21 11.4 0.3 1.6 1 0 0 1 1 1 0 YjeF-related protein N-terminus 4HBT_2 PF13279.6 RKO96976.1 - 2.1e-06 28.2 0.0 3.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 RKO96976.1 - 0.072 13.5 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily Na_H_Exchanger PF00999.21 RKO96977.1 - 3.2e-71 240.1 33.6 3.7e-71 239.9 33.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PNP_UDP_1 PF01048.20 RKO96978.1 - 9.2e-19 67.6 5.2 1.1e-18 67.4 5.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily XFP_N PF09364.10 RKO96979.1 - 6.9e-50 169.9 0.0 4.3e-46 157.4 0.0 3.0 2 1 0 2 2 2 2 XFP N-terminal domain XFP_C PF09363.10 RKO96979.1 - 1.6e-41 142.0 0.0 3.3e-41 141.0 0.0 1.5 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 RKO96979.1 - 5.1e-06 26.3 0.0 0.002 17.9 0.0 2.9 1 1 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Spt20 PF12090.8 RKO96979.1 - 4 7.0 6.9 6.5 6.3 6.9 1.2 1 0 0 1 1 1 0 Spt20 family NAD_kinase PF01513.21 RKO96980.1 - 5.6e-35 121.0 0.0 6.6e-35 120.7 0.0 1.0 1 0 0 1 1 1 1 ATP-NAD kinase RVT_1 PF00078.27 RKO96982.1 - 0.034 13.7 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Biotin_lipoyl PF00364.22 RKO96983.1 - 2.2e-06 27.4 0.1 3.9e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Hist_deacetyl PF00850.19 RKO96984.1 - 3.5e-68 230.3 0.3 5.6e-68 229.7 0.3 1.3 1 1 0 1 1 1 1 Histone deacetylase domain Lipase_GDSL PF00657.22 RKO96985.1 - 6.9e-09 36.0 0.0 9.7e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 RKO96985.1 - 6.5e-08 33.2 0.1 1.8e-07 31.7 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HHH_2 PF12826.7 RKO96985.1 - 0.16 12.1 0.1 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif zf-RVT PF13966.6 RKO96986.1 - 0.41 11.4 5.0 0.22 12.3 1.4 2.2 2 1 0 2 2 2 0 zinc-binding in reverse transcriptase DUF2722 PF10846.8 RKO96987.1 - 0.0015 17.6 11.7 0.0015 17.6 11.7 3.5 3 1 0 3 3 3 2 Protein of unknown function (DUF2722) SET PF00856.28 RKO96987.1 - 0.0049 17.3 4.0 0.8 10.1 0.4 2.4 2 0 0 2 2 2 2 SET domain Spt20 PF12090.8 RKO96987.1 - 2.2 7.8 61.2 0.1 12.2 21.8 3.3 3 0 0 3 3 3 0 Spt20 family FHIPEP PF00771.20 RKO96987.1 - 3.5 6.0 12.0 0.73 8.2 0.9 2.2 2 0 0 2 2 2 0 FHIPEP family Macoilin PF09726.9 RKO96987.1 - 5.2 5.5 14.0 4.1 5.8 5.8 2.2 2 0 0 2 2 2 0 Macoilin family RLL PF10036.9 RKO96987.1 - 8.2 6.2 17.9 4.1 7.2 4.5 3.0 3 0 0 3 3 3 0 RNA transcription, translation and transport factor protein Peptidase_S49_N PF08496.10 RKO96987.1 - 10 6.2 8.7 5 7.2 1.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal GATA PF00320.27 RKO96988.1 - 4.6e-16 58.1 3.8 5.7e-16 57.8 3.8 1.2 1 0 0 1 1 1 1 GATA zinc finger Nudix_N_2 PF14803.6 RKO96988.1 - 0.0065 16.4 1.0 0.011 15.7 1.0 1.4 1 0 0 1 1 1 1 Nudix N-terminal Zn-ribbon_8 PF09723.10 RKO96988.1 - 0.01 15.9 0.4 0.017 15.2 0.4 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 RKO96988.1 - 0.33 10.7 3.7 13 5.7 1.4 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain HECT PF00632.25 RKO96989.1 - 1.9e-88 296.9 0.0 2.2e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Phosducin PF02114.16 RKO96990.1 - 2.1e-12 46.5 0.1 3.7e-12 45.8 0.1 1.3 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 RKO96990.1 - 0.00011 22.1 0.0 0.00022 21.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DUF2870 PF11069.8 RKO96990.1 - 0.018 15.4 3.5 0.075 13.4 3.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) UPF0154 PF03672.13 RKO96990.1 - 0.24 11.4 1.9 0.43 10.6 0.7 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EB PF01683.18 RKO96992.1 - 0.75 10.1 5.8 4.1 7.8 5.8 2.2 1 1 0 1 1 1 0 EB module IGPD PF00475.18 RKO96993.1 - 1.3e-62 210.4 1.4 1.5e-62 210.1 1.4 1.1 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase CH_2 PF06294.11 RKO96994.1 - 3.7e-32 110.3 0.0 4.2e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 RKO96994.1 - 1.1e-10 41.2 0.0 1.2e-10 41.0 0.0 1.1 1 0 0 1 1 1 1 CAMSAP CH domain Mlh1_C PF16413.5 RKO96995.1 - 2.4e-69 233.7 0.0 3.6e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 RKO96995.1 - 2.2e-26 91.9 0.0 3.3e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 RKO96995.1 - 4.4e-12 46.0 0.0 7.9e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 RKO96995.1 - 3.1e-07 30.9 0.0 6.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase STAS_2 PF13466.6 RKO96995.1 - 9.6 6.6 8.0 11 6.5 0.6 3.7 4 0 0 4 4 4 0 STAS domain WD40 PF00400.32 RKO96996.1 - 0.00019 22.1 0.2 0.22 12.5 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat BolA PF01722.18 RKO96997.1 - 1.6e-11 44.3 0.0 6.1e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 BolA-like protein TFIID-31kDa PF02291.15 RKO96998.1 - 4.2e-44 149.5 0.0 4.6e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 RKO96998.1 - 4.5e-07 29.8 0.0 7.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 RKO96998.1 - 1.4e-05 25.4 0.0 2.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 RKO96998.1 - 0.00023 21.5 0.1 0.00029 21.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 RKO96998.1 - 0.00053 20.1 0.0 0.00063 19.8 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold AAA_lid_2 PF17863.1 RKO96998.1 - 0.013 15.3 0.3 0.019 14.8 0.3 1.2 1 0 0 1 1 1 0 AAA lid domain TIP49_C PF17856.1 RKO96998.1 - 0.074 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 AAA-lid domain TFIID-18kDa PF02269.16 RKO96998.1 - 0.088 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF1931 PF09123.11 RKO96998.1 - 0.099 12.8 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Tubulin PF00091.25 RKO96999.1 - 1.2e-31 110.5 0.0 1.8e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 RKO96999.1 - 0.01 15.1 0.1 0.047 12.9 0.2 1.9 1 1 1 2 2 2 0 Tubulin like Rho_GDI PF02115.17 RKO97000.1 - 1.1e-58 198.2 0.0 1.2e-58 198.1 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Meth_synt_2 PF01717.18 RKO97002.1 - 1.5e-150 500.9 0.0 3.4e-143 476.8 0.0 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 RKO97002.1 - 8.1e-108 360.6 0.0 8.4e-101 337.6 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain Mitofilin PF09731.9 RKO97004.1 - 3.1e-43 148.6 9.6 4.7e-43 148.0 9.6 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF826 PF05696.11 RKO97004.1 - 0.011 15.8 0.3 0.026 14.6 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF826) betaPIX_CC PF16523.5 RKO97004.1 - 1.6 8.6 6.1 0.52 10.2 3.0 1.8 2 1 0 2 2 2 0 betaPIX coiled coil HSCB_C PF07743.13 RKO97004.1 - 6 7.4 12.2 3.8 8.1 5.6 2.6 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain KH_8 PF17903.1 RKO97005.1 - 5.1e-30 103.4 0.0 1e-29 102.5 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 RKO97005.1 - 0.00079 19.2 0.0 0.0031 17.3 0.0 2.0 2 1 0 2 2 2 1 KH domain Alpha_GJ PF03229.13 RKO97005.1 - 0.82 10.2 4.8 1.1 9.8 0.3 2.4 2 0 0 2 2 2 0 Alphavirus glycoprotein J HGTP_anticodon2 PF12745.7 RKO97006.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MFS_2 PF13347.6 RKO97007.1 - 2e-06 26.7 12.3 4.1e-06 25.6 11.1 1.8 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 RKO97007.1 - 4.1e-06 26.0 16.8 1.1e-05 24.6 16.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily BBS1 PF14779.6 RKO97008.1 - 0.046 13.1 0.3 0.15 11.5 0.2 1.8 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 1 PTPA PF03095.15 RKO97009.1 - 9.5e-117 389.7 0.0 1.1e-116 389.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Glyco_trans_2_3 PF13632.6 RKO97010.1 - 6.9e-26 91.4 5.6 6.9e-26 91.4 5.6 1.9 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKO97010.1 - 2.6e-12 47.1 0.7 3.6e-12 46.7 0.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Methyltransf_25 PF13649.6 RKO97012.1 - 3e-17 63.1 0.0 6.7e-17 62.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Dala_Dala_lig_C PF07478.13 RKO97012.1 - 2.2e-16 60.0 0.0 3.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Methyltransf_31 PF13847.6 RKO97012.1 - 1.5e-12 47.5 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO97012.1 - 1.7e-11 44.6 0.0 3.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO97012.1 - 1.3e-08 34.9 0.0 2.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 RKO97012.1 - 8e-07 28.6 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 RKO97012.1 - 4.5e-06 27.3 0.0 9.3e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKO97012.1 - 5.7e-05 22.7 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 RKO97012.1 - 0.0004 19.9 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase ATPgrasp_Ter PF15632.6 RKO97012.1 - 0.017 14.9 0.0 0.17 11.7 0.0 2.3 1 1 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 RKO97012.1 - 0.043 13.9 0.0 0.15 12.1 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain RINGv PF12906.7 RKO97013.1 - 8.1e-17 61.1 9.0 1.6e-16 60.1 9.0 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 RKO97013.1 - 0.0013 19.0 7.1 0.0013 19.0 7.1 1.8 2 0 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 RKO97013.1 - 0.025 14.6 2.2 0.025 14.6 2.2 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-trcl PF13451.6 RKO97013.1 - 0.18 11.7 1.4 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain Mito_fiss_reg PF05308.11 RKO97013.1 - 1.1 9.3 5.7 1.6 8.7 5.7 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 RKO97013.1 - 6 6.2 11.2 7.9 5.9 11.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CarS-like PF01864.17 RKO97015.1 - 0.064 13.2 0.3 0.098 12.6 0.3 1.2 1 0 0 1 1 1 0 CDP-archaeol synthase TRM PF02005.16 RKO97016.1 - 8.3e-119 397.1 0.0 9.8e-119 396.9 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 RKO97016.1 - 0.00083 19.2 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 RKO97016.1 - 0.018 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 RKO97016.1 - 0.048 13.2 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 RKO97016.1 - 0.082 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PPK2 PF03976.14 RKO97016.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) PrmA PF06325.13 RKO97016.1 - 0.22 10.9 0.2 0.34 10.3 0.2 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pyr_redox_2 PF07992.14 RKO97019.1 - 9.5e-08 31.6 0.3 0.0059 15.9 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RKO97019.1 - 5.5e-07 29.7 0.0 1.3e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 RKO97019.1 - 4.7e-06 26.0 0.4 0.0018 17.6 0.0 2.1 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.6 RKO97019.1 - 2.2e-05 24.5 0.1 6.1e-05 23.1 0.0 1.9 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 RKO97019.1 - 0.00029 20.2 0.2 0.071 12.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO97019.1 - 0.003 18.1 0.0 0.98 10.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RKO97019.1 - 0.0061 15.8 0.3 0.048 12.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 RKO97019.1 - 0.0089 14.9 0.1 0.019 13.9 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.14 RKO97019.1 - 0.016 13.9 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 RKO97019.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 RKO97019.1 - 0.09 13.0 0.0 6.7 7.0 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 RKO97019.1 - 0.13 11.3 0.2 0.22 10.5 0.0 1.4 2 0 0 2 2 2 0 Lycopene cyclase protein Y_phosphatase3 PF13350.6 RKO97021.1 - 5.5e-41 141.1 0.0 6.5e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 RKO97021.1 - 8.2e-08 32.0 0.0 1.7e-07 31.0 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RKO97021.1 - 0.00025 20.7 0.0 0.00036 20.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 RKO97021.1 - 0.019 13.9 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 RKO97021.1 - 0.063 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RTA1 PF04479.13 RKO97022.1 - 5e-41 140.6 10.0 7.6e-41 140.0 10.0 1.2 1 0 0 1 1 1 1 RTA1 like protein RhoGAP PF00620.27 RKO97023.1 - 1.8e-25 89.6 0.0 7.8e-20 71.3 0.0 2.7 2 1 0 2 2 2 2 RhoGAP domain ANAPC4_WD40 PF12894.7 RKO97023.1 - 1.9e-05 24.8 0.0 0.036 14.4 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKO97023.1 - 2.6e-05 24.9 0.0 9.2 7.3 0.0 5.3 4 0 0 4 4 4 1 WD domain, G-beta repeat Serinc PF03348.15 RKO97024.1 - 2.5e-83 280.4 30.0 1.4e-80 271.3 30.0 2.0 1 1 0 1 1 1 1 Serine incorporator (Serinc) DUF3043 PF11241.8 RKO97024.1 - 0.016 15.3 0.6 0.033 14.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2427 PF10348.9 RKO97025.1 - 2.8e-12 46.3 10.0 2.8e-08 33.5 1.2 3.1 3 1 1 4 4 4 2 Domain of unknown function (DUF2427) Ytp1 PF10355.9 RKO97025.1 - 2.5e-10 40.1 0.8 4.4e-10 39.2 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) NOA36 PF06524.12 RKO97026.1 - 0.46 9.8 2.1 0.62 9.3 2.1 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 RKO97026.1 - 0.8 10.1 4.8 0.48 10.8 3.0 1.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GST_N_2 PF13409.6 RKO97027.1 - 2.1e-15 56.8 0.0 7.2e-15 55.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RKO97027.1 - 2.2e-10 40.4 0.7 5.4e-10 39.1 0.7 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 RKO97027.1 - 3.4e-07 30.4 0.0 7.7e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RKO97027.1 - 4.3e-05 23.6 0.0 0.0001 22.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 RKO97027.1 - 0.00024 21.5 0.0 0.018 15.5 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 RKO97027.1 - 0.0018 18.0 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Coatomer_WDAD PF04053.14 RKO97028.1 - 8.2e-141 470.1 0.0 2.6e-140 468.4 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 RKO97028.1 - 6.1e-42 140.8 3.9 1e-07 32.5 0.1 8.3 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97028.1 - 3.8e-11 43.1 1.0 0.99 9.7 0.0 6.8 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 RKO97028.1 - 4.2e-05 23.5 0.1 0.55 10.3 0.0 4.7 3 2 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 RKO97028.1 - 0.0024 16.6 1.5 0.22 10.1 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin Nup120/160 TPR_2 PF07719.17 RKO97028.1 - 0.43 10.8 3.8 0.48 10.7 0.7 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_15 PF00723.21 RKO97030.1 - 3.1e-50 171.3 0.0 9e-49 166.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 SUA5 PF03481.13 RKO97031.1 - 1.6e-11 44.9 0.0 1.9e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Inj_translocase PF16928.5 RKO97031.1 - 0.12 11.9 0.0 0.69 9.3 0.0 1.9 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome AAA_8 PF12780.7 RKO97032.1 - 8.6e-100 333.3 0.0 8.6e-100 333.3 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKO97032.1 - 9.8e-84 279.9 0.8 9.8e-84 279.9 0.8 3.6 4 0 0 4 4 4 1 ATP-binding dynein motor region Dynein_C PF18199.1 RKO97032.1 - 3.7e-77 259.6 0.0 1.1e-76 258.0 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RKO97032.1 - 1e-57 194.6 0.0 3.9e-57 192.7 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKO97032.1 - 1.3e-54 184.4 0.0 2.7e-54 183.4 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 RKO97032.1 - 8.4e-49 166.4 7.6 1.6e-48 165.5 7.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 RKO97032.1 - 1.3e-44 151.1 0.0 7.2e-44 148.7 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RKO97032.1 - 6.3e-14 52.0 0.0 2.3e-13 50.2 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKO97032.1 - 8.5e-11 42.0 0.0 4.3e-07 30.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 RKO97032.1 - 7.5e-07 29.6 0.0 0.00083 19.8 0.0 3.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKO97032.1 - 8.8e-07 29.3 0.6 0.00069 19.9 0.0 4.4 4 0 0 4 4 4 1 AAA domain DHR10 PF18595.1 RKO97032.1 - 0.0011 19.0 5.5 0.0011 19.0 5.5 3.1 3 0 0 3 3 2 1 Designed helical repeat protein 10 domain AAA_16 PF13191.6 RKO97032.1 - 0.0018 18.7 0.7 0.55 10.6 0.0 4.0 2 2 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 RKO97032.1 - 0.037 13.2 0.0 2.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Tropomyosin PF00261.20 RKO97032.1 - 0.047 13.1 17.4 0.018 14.4 3.7 2.4 2 0 0 2 2 2 0 Tropomyosin Exonuc_VII_L PF02601.15 RKO97032.1 - 0.19 11.3 8.3 3.2 7.2 3.8 2.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit DivIC PF04977.15 RKO97032.1 - 0.37 10.6 4.3 0.41 10.5 1.7 2.6 2 0 0 2 2 1 0 Septum formation initiator SKA2 PF16740.5 RKO97032.1 - 4.5 7.1 9.3 0.27 11.0 0.8 2.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Tyrosinase PF00264.20 RKO97033.1 - 2.8e-27 96.5 4.0 2.8e-25 89.9 4.0 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Lipase_GDSL_2 PF13472.6 RKO97034.1 - 7.3e-16 59.1 0.0 6.6e-14 52.7 0.0 2.7 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RKO97034.1 - 1.8e-06 28.0 0.0 4e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DAZAP2 PF11029.8 RKO97034.1 - 0.031 15.2 0.0 0.071 14.0 0.0 1.6 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) Ldh_1_C PF02866.18 RKO97035.1 - 4.8e-49 166.5 0.2 7.8e-49 165.8 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 RKO97035.1 - 4.7e-46 156.4 0.4 9.4e-46 155.4 0.1 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 RKO97035.1 - 0.012 14.7 0.0 0.026 13.5 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 RKO97035.1 - 0.12 12.0 1.9 3.8 7.0 0.1 2.7 2 1 1 3 3 3 0 Family 4 glycosyl hydrolase Ku PF02735.16 RKO97036.1 - 4.9e-09 36.2 0.0 0.0017 18.1 0.0 3.0 2 1 0 2 2 2 2 Ku70/Ku80 beta-barrel domain Prominin PF05478.11 RKO97037.1 - 6.4e-11 41.0 0.1 1e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Prominin Tweety PF04906.13 RKO97037.1 - 1.6e-05 23.7 4.9 0.0054 15.4 0.1 2.5 2 0 0 2 2 2 2 Tweety Apolipoprotein PF01442.18 RKO97037.1 - 0.027 14.4 0.5 0.44 10.4 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain SUR7 PF06687.12 RKO97037.1 - 0.043 13.4 11.7 0.022 14.4 2.0 2.7 2 0 0 2 2 2 0 SUR7/PalI family DUF2207 PF09972.9 RKO97037.1 - 0.17 10.6 3.3 0.17 10.6 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Baculo_PEP_C PF04513.12 RKO97037.1 - 0.23 11.5 35.8 0.22 11.5 9.1 4.5 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Duo1 PF08651.10 RKO97037.1 - 0.35 10.7 1.8 4.5 7.1 0.2 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 DUF1664 PF07889.12 RKO97037.1 - 0.38 10.8 2.5 25 4.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) WXG100 PF06013.12 RKO97037.1 - 1 9.6 7.3 4.5 7.6 0.1 4.1 4 0 0 4 4 4 0 Proteins of 100 residues with WXG NPV_P10 PF05531.12 RKO97037.1 - 4.3 7.9 20.4 6.5 7.3 1.7 5.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.25 RKO97038.1 - 3.6e-16 59.3 0.0 5.2e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 RKO97038.1 - 6.3e-05 23.7 1.0 0.6 11.1 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 RKO97038.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 RKO97038.1 - 0.00064 19.8 5.1 16 6.1 0.1 5.6 5 0 0 5 5 5 1 HEAT repeat APH PF01636.23 RKO97038.1 - 0.0022 18.0 0.1 0.0073 16.3 0.1 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1970 PF09301.10 RKO97038.1 - 4.7 7.5 5.6 26 5.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1970) ATG22 PF11700.8 RKO97039.1 - 3.4e-39 134.8 4.4 4.1e-39 134.5 4.4 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like GP68 PF17469.2 RKO97039.1 - 0.34 11.3 5.2 1.6 9.2 0.1 2.8 3 0 0 3 3 3 0 Phage protein Gp68 TssN PF17555.2 RKO97039.1 - 7 6.0 5.6 9.7 5.5 5.6 1.1 1 0 0 1 1 1 0 Type VI secretion system, TssN Sec1 PF00995.23 RKO97041.1 - 4e-05 23.1 0.0 0.00038 19.8 0.0 2.0 2 0 0 2 2 2 1 Sec1 family HSP70 PF00012.20 RKO97042.1 - 3.5e-267 887.5 14.4 4e-267 887.3 14.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RKO97042.1 - 1.7e-13 50.1 11.5 4.6e-13 48.7 3.1 2.8 3 0 0 3 3 3 2 MreB/Mbl protein FGGY_C PF02782.16 RKO97042.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 RKO97042.1 - 0.012 16.0 5.5 10 6.6 0.2 4.0 3 1 0 3 3 3 0 Cell division protein FtsA DUF5333 PF17267.2 RKO97042.1 - 0.027 14.6 5.6 0.39 10.9 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5333) cwf21 PF08312.12 RKO97042.1 - 0.14 12.3 3.9 0.36 11.0 2.0 2.4 2 0 0 2 2 2 0 cwf21 domain Arc_PepC PF06819.11 RKO97042.1 - 4.3 7.5 7.7 4.9 7.3 3.3 3.0 3 1 1 4 4 4 0 Archaeal Peptidase A24 C-terminal Domain SKA2 PF16740.5 RKO97043.1 - 0.12 12.2 3.1 0.22 11.3 0.0 2.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 Helicase_C PF00271.31 RKO97044.1 - 1.1e-11 45.0 0.0 2.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 RKO97044.1 - 3.6e-09 36.9 0.1 5.8e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 RKO97044.1 - 6.6e-08 32.5 0.1 1.1e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 RKO97044.1 - 1.6e-05 25.2 0.1 3.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO97044.1 - 0.00038 20.8 0.1 0.00081 19.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 RKO97044.1 - 0.048 14.1 0.0 0.081 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 RKO97045.1 - 1.1e-103 345.7 0.0 2.1e-103 344.8 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 RKO97045.1 - 7.7e-35 119.8 0.3 2.5e-34 118.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO97045.1 - 1.5e-16 60.8 0.0 3.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKO97045.1 - 2e-11 44.2 1.1 4.3e-11 43.1 0.2 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 RKO97045.1 - 1.1e-07 30.9 0.0 1.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 RKO97045.1 - 1.7e-06 27.9 0.0 3.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 RKO97045.1 - 0.0037 16.2 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Cu-oxidase PF00394.22 RKO97046.1 - 2.7e-34 118.6 0.0 5.8e-34 117.5 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RKO97046.1 - 8.2e-27 93.6 9.4 2.3e-23 82.4 2.6 4.8 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 RKO97046.1 - 8.9e-27 93.5 2.0 7.1e-26 90.6 0.1 3.2 4 1 0 4 4 4 1 Multicopper oxidase DUF3498 PF12004.8 RKO97047.1 - 0.052 12.7 0.1 0.052 12.7 0.1 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3498) Sas10_Utp3 PF04000.15 RKO97048.1 - 5.4e-11 43.0 0.5 1.5e-10 41.5 0.5 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Coat_F PF07875.12 RKO97048.1 - 1.4 9.2 4.8 13 6.1 0.4 2.6 2 0 0 2 2 2 0 Coat F domain NAD_binding_6 PF08030.12 RKO97050.1 - 6.3e-33 114.1 0.0 1.1e-32 113.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 RKO97050.1 - 3.3e-22 78.6 0.0 8.4e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 RKO97050.1 - 8.4e-19 67.9 11.5 1.9e-18 66.8 11.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.21 RKO97050.1 - 0.037 14.7 0.0 0.19 12.4 0.0 2.1 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Flavi_M PF01004.19 RKO97050.1 - 0.091 12.5 3.8 0.15 11.8 0.8 2.3 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M Peptidase_U4 PF03419.13 RKO97050.1 - 1.4 8.1 9.4 0.046 13.0 2.3 2.0 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Topoisom_bac PF01131.20 RKO97051.1 - 3.7e-100 335.8 0.0 4.5e-100 335.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 RKO97051.1 - 9e-20 70.8 0.0 2.4e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 Toprim domain TPR_19 PF14559.6 RKO97052.1 - 1.5e-20 73.5 15.0 6.6e-05 23.3 0.1 6.5 6 1 1 7 7 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO97052.1 - 2.6e-19 69.2 19.7 0.00013 22.2 0.4 5.6 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RKO97052.1 - 6.5e-11 42.1 8.6 0.0036 18.0 0.1 8.1 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO97052.1 - 1.2e-10 41.3 11.4 0.073 13.7 0.1 9.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKO97052.1 - 7.8e-10 38.1 27.8 0.0025 17.8 0.1 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 RKO97052.1 - 9.8e-09 35.4 18.3 0.048 13.9 2.5 8.0 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKO97052.1 - 2.2e-08 34.6 9.6 0.039 14.6 0.1 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKO97052.1 - 3.1e-07 30.0 9.7 0.14 12.2 0.3 6.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO97052.1 - 8.9e-06 25.8 3.8 3.3 7.9 0.0 5.6 5 2 1 6 6 6 2 Tetratricopeptide repeat Coatomer_E PF04733.14 RKO97052.1 - 8.8e-05 22.0 5.4 0.088 12.2 0.2 3.6 3 1 1 4 4 4 2 Coatomer epsilon subunit TPR_8 PF13181.6 RKO97052.1 - 8.9e-05 22.4 7.6 1.4 9.3 0.0 6.8 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 RKO97052.1 - 0.00044 20.0 4.3 4.9 7.2 0.2 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.14 RKO97052.1 - 0.00052 20.4 0.1 27 5.8 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKO97052.1 - 0.0014 18.9 6.5 13 6.5 0.0 7.2 9 0 0 9 9 9 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 RKO97052.1 - 0.0025 17.4 1.1 14 5.3 0.0 4.2 3 1 1 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 RKO97052.1 - 0.0071 16.5 6.6 38 4.9 0.0 5.9 7 0 0 7 7 6 0 PPR repeat TPR_1 PF00515.28 RKO97052.1 - 0.039 13.8 30.2 1.1 9.2 0.1 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR_2 PF13041.6 RKO97052.1 - 0.039 14.1 2.6 47 4.3 0.1 4.7 5 0 0 5 5 5 0 PPR repeat family TPR_3 PF07720.12 RKO97052.1 - 4.5 7.4 20.4 3.1 7.9 1.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Aa_trans PF01490.18 RKO97053.1 - 2.4e-77 260.4 27.7 2.7e-77 260.2 27.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 RKO97053.1 - 1.5e-08 34.1 19.5 1.5e-08 34.1 19.5 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2408 PF10303.9 RKO97054.1 - 7e-36 123.8 1.2 5.7e-19 69.0 0.0 4.1 3 1 1 4 4 4 3 Protein of unknown function (DUF2408) Alpha-2-MRAP_C PF06401.11 RKO97054.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain Allexi_40kDa PF05549.11 RKO97054.1 - 0.2 11.1 1.4 2.9 7.3 0.1 2.7 3 0 0 3 3 3 0 Allexivirus 40kDa protein PTPLA PF04387.14 RKO97055.1 - 7.7e-48 162.3 13.3 1.2e-47 161.7 13.3 1.3 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA LRR_6 PF13516.6 RKO97056.1 - 2.4e-06 27.2 1.5 0.0018 18.2 0.1 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 RKO97056.1 - 0.024 15.1 0.0 0.13 12.7 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ATP11 PF06644.11 RKO97057.1 - 5.4e-54 183.8 0.0 6.2e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Phage_sheath_1 PF04984.14 RKO97057.1 - 0.15 11.9 1.5 1.6 8.6 0.3 2.2 2 0 0 2 2 2 0 Phage tail sheath protein subtilisin-like domain CN_hydrolase PF00795.22 RKO97058.1 - 3.9e-61 206.7 0.4 4.4e-61 206.5 0.4 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Chs7 PF12271.8 RKO97059.1 - 2.7e-113 378.1 20.5 3.2e-113 377.9 20.5 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone ATG27 PF09451.10 RKO97059.1 - 0.16 11.8 0.3 0.34 10.7 0.3 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 Phage_holin_2_2 PF10746.9 RKO97059.1 - 0.18 11.5 1.1 1.1 9.0 0.2 2.4 2 0 0 2 2 2 0 Phage holin T7 family, holin superfamily II WD40 PF00400.32 RKO97060.1 - 1.8e-05 25.4 0.3 0.02 15.8 0.1 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat Ribosomal_S3Ae PF01015.18 RKO97061.1 - 2.3e-88 295.0 1.6 2.7e-88 294.8 1.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Cuticle_4 PF15955.5 RKO97062.1 - 0.069 13.9 0.4 0.13 13.0 0.4 1.5 1 0 0 1 1 1 0 Cuticle protein ASH PF15780.5 RKO97063.1 - 9.8e-07 28.9 0.1 12 6.2 0.0 5.4 5 1 1 6 6 6 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 RKO97063.1 - 0.2 11.5 0.1 90 3.0 0.0 4.1 5 0 0 5 5 5 0 MSP (Major sperm protein) domain RhoGAP PF00620.27 RKO97064.1 - 5.5e-06 26.3 0.0 5.2e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain FAD_binding_2 PF00890.24 RKO97065.1 - 6.3e-76 256.1 3.4 7.6e-76 255.8 3.4 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 RKO97065.1 - 1.2e-17 63.8 0.2 3.1e-17 62.5 0.0 1.8 2 0 0 2 2 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 RKO97065.1 - 2.5e-14 53.7 1.9 5.8e-14 52.4 1.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RKO97065.1 - 9.6e-09 35.4 3.3 2.9e-08 33.8 0.3 3.1 4 0 0 4 4 3 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 RKO97065.1 - 1.9e-08 34.1 2.1 1.9e-08 34.1 2.1 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 RKO97065.1 - 8.6e-08 31.9 3.0 5.1e-05 22.7 0.3 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 RKO97065.1 - 2.8e-06 26.8 1.6 0.00033 20.0 0.7 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RKO97065.1 - 5.5e-06 25.9 2.4 9.1e-06 25.1 2.4 1.4 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 RKO97065.1 - 7.9e-05 22.0 0.5 0.002 17.4 0.2 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.27 RKO97065.1 - 8.4e-05 23.1 0.7 0.00098 19.6 0.3 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RKO97065.1 - 0.00013 20.8 2.5 0.00069 18.4 0.2 2.7 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 RKO97065.1 - 0.00044 19.4 2.3 0.00047 19.4 1.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 RKO97065.1 - 0.012 14.6 0.2 0.018 14.1 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 RKO97065.1 - 0.03 13.6 0.7 0.058 12.7 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 RKO97065.1 - 0.051 13.6 0.2 0.21 11.5 0.2 2.1 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 RKO97065.1 - 0.061 12.6 0.1 0.15 11.2 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.22 RKO97067.1 - 1.5e-59 200.2 0.4 2e-59 199.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO97067.1 - 6.6e-37 126.4 0.1 1e-36 125.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO97067.1 - 2.2e-14 53.3 0.1 2.8e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RKO97067.1 - 6.2e-07 29.0 0.1 7.6e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 RKO97067.1 - 3.1e-05 23.6 0.1 0.00021 20.9 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKO97067.1 - 6.8e-05 22.9 0.0 0.00013 22.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 RKO97067.1 - 0.00015 21.2 0.1 0.00018 20.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 RKO97067.1 - 0.00037 20.5 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 RKO97067.1 - 0.0086 15.9 0.1 0.03 14.1 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 RKO97067.1 - 0.029 13.8 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TetR_C_16 PF17920.1 RKO97067.1 - 0.097 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA_7 PF12775.7 RKO97067.1 - 0.1 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 RKO97067.1 - 0.14 12.4 0.1 15 5.8 0.0 2.2 1 1 0 2 2 2 0 AAA domain Acetyltransf_3 PF13302.7 RKO97068.1 - 0.00053 20.7 0.0 0.095 13.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF688 PF05097.12 RKO97068.1 - 0.055 12.6 1.9 5.2 6.1 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF688) Acetyltransf_1 PF00583.25 RKO97068.1 - 0.19 12.0 0.0 0.71 10.1 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF4611 PF15387.6 RKO97068.1 - 0.28 11.4 6.7 1.8 8.8 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) WD40 PF00400.32 RKO97069.1 - 2.4e-08 34.5 1.2 0.00018 22.2 0.7 2.6 2 1 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97069.1 - 1.3e-05 25.4 0.0 0.0058 16.9 0.0 2.1 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO97069.1 - 0.0016 17.5 0.0 0.23 10.4 0.0 2.0 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cupin_8 PF13621.6 RKO97070.1 - 2.3e-14 53.8 0.1 1.6e-10 41.1 0.0 2.4 1 1 1 2 2 2 2 Cupin-like domain JmjC PF02373.22 RKO97070.1 - 5e-12 46.3 0.0 1.8e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 RKO97070.1 - 0.042 13.6 0.0 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 Cupin domain Cupin_4 PF08007.12 RKO97070.1 - 0.089 12.2 0.0 0.42 10.0 0.0 2.0 1 1 0 1 1 1 0 Cupin superfamily protein Elongin_A PF06881.11 RKO97070.1 - 0.13 12.8 0.2 0.37 11.3 0.0 1.8 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A MIT PF04212.18 RKO97071.1 - 0.015 15.4 4.7 0.029 14.4 4.7 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 RKO97071.1 - 0.2 11.9 4.2 0.33 11.2 4.2 1.3 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Chitin_synth_2 PF03142.15 RKO97072.1 - 3.5e-234 778.3 0.0 5.3e-234 777.7 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 RKO97072.1 - 4.7e-12 46.2 1.9 2.6e-11 43.8 1.9 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 RKO97072.1 - 1.7e-11 44.5 0.0 8.9e-11 42.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 RKO97072.1 - 0.02 14.4 0.0 0.62 9.5 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 RKO97072.1 - 0.038 13.8 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Cyt-b5 PF00173.28 RKO97072.1 - 0.12 12.5 0.0 0.85 9.8 0.0 2.2 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain WD40 PF00400.32 RKO97074.1 - 4.8e-14 52.5 0.1 1.2e-05 25.9 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 RKO97074.1 - 0.006 15.3 1.2 0.0063 15.2 0.3 1.7 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PTS_2-RNA PF01885.16 RKO97075.1 - 1.2e-60 204.6 0.0 1.4e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PIN_10 PF18478.1 RKO97075.1 - 0.069 13.4 0.4 0.26 11.5 0.1 2.0 1 1 1 2 2 2 0 PIN like domain Pkinase PF00069.25 RKO97077.1 - 1.8e-62 211.1 0.0 2.3e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97077.1 - 1e-28 100.4 0.0 1.3e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RKO97077.1 - 1.5e-06 27.4 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKO97077.1 - 0.00055 19.4 0.1 0.00095 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO97077.1 - 0.023 14.6 0.2 0.056 13.4 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 RKO97077.1 - 0.025 14.2 0.1 0.35 10.5 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 RKO97077.1 - 0.027 13.2 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S24 PF00717.23 RKO97078.1 - 1.4e-12 47.4 0.0 2.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 RKO97078.1 - 1.8e-08 34.3 0.0 4e-08 33.2 0.0 1.6 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Cu-oxidase_3 PF07732.15 RKO97081.1 - 1.9e-33 115.0 1.3 4.3e-33 113.8 1.3 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 RKO97081.1 - 5.2e-24 85.2 1.3 6.1e-23 81.7 0.0 2.8 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 RKO97081.1 - 2.6e-08 33.7 0.2 2.6e-08 33.7 0.2 3.3 3 1 0 3 3 3 1 Multicopper oxidase ARS2 PF04959.13 RKO97082.1 - 0.19 12.1 0.3 0.25 11.7 0.3 1.1 1 0 0 1 1 1 0 Arsenite-resistance protein 2 AAA_11 PF13086.6 RKO97084.1 - 2.2e-58 198.1 0.4 5e-58 196.9 0.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 RKO97084.1 - 1.4e-54 184.8 0.0 2e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 RKO97084.1 - 6.9e-14 52.0 1.4 1.1e-07 31.8 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 RKO97084.1 - 4.6e-10 40.0 0.0 1.1e-08 35.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 RKO97084.1 - 9.4e-10 38.6 0.0 0.0065 16.2 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 RKO97084.1 - 6.2e-06 26.5 0.1 0.00049 20.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RKO97084.1 - 1.7e-05 24.9 0.0 0.00016 21.7 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 RKO97084.1 - 4.8e-05 23.8 0.3 0.00018 21.9 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 RKO97084.1 - 0.00018 21.9 0.0 0.0024 18.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 RKO97084.1 - 0.00046 19.2 0.0 0.00096 18.2 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain PIF1 PF05970.14 RKO97084.1 - 0.00091 18.5 0.0 0.52 9.4 0.0 2.3 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.14 RKO97084.1 - 0.0011 18.9 2.7 0.0024 17.7 0.0 2.5 2 1 0 2 2 2 1 Helicase NTPase_1 PF03266.15 RKO97084.1 - 0.0015 18.5 0.1 0.87 9.5 0.0 2.5 2 0 0 2 2 2 1 NTPase PhoH PF02562.16 RKO97084.1 - 0.0026 17.2 0.0 0.092 12.2 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.9 RKO97084.1 - 0.0032 16.8 1.5 0.075 12.2 0.0 2.6 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 RKO97084.1 - 0.006 16.3 0.2 0.23 11.2 0.0 3.1 4 0 0 4 4 3 1 IstB-like ATP binding protein SRP54 PF00448.22 RKO97084.1 - 0.0087 15.7 0.0 0.096 12.3 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 RKO97084.1 - 0.0096 15.3 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RKO97084.1 - 0.011 15.7 0.0 0.043 13.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RKO97084.1 - 0.012 15.2 0.9 0.28 10.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 RKO97084.1 - 0.016 15.0 0.2 0.19 11.5 0.2 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase RNA_helicase PF00910.22 RKO97084.1 - 0.021 15.2 0.0 0.058 13.8 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 RKO97084.1 - 0.026 14.0 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 RKO97084.1 - 0.031 13.3 0.0 0.077 12.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 RKO97084.1 - 0.037 14.1 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 RKO97084.1 - 0.044 12.8 0.6 0.11 11.5 0.0 1.9 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ATPase PF06745.13 RKO97084.1 - 0.046 13.1 0.0 0.091 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 RKO97084.1 - 0.052 13.3 0.0 0.57 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Flavi_DEAD PF07652.14 RKO97084.1 - 0.058 13.4 0.1 0.2 11.6 0.0 2.0 2 0 0 2 2 1 0 Flavivirus DEAD domain AAA_33 PF13671.6 RKO97084.1 - 0.059 13.5 0.6 0.18 11.9 0.0 2.2 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.6 RKO97084.1 - 0.069 13.7 0.0 0.29 11.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.12 RKO97084.1 - 0.087 12.6 0.0 0.37 10.5 0.0 2.0 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain UvrD-helicase PF00580.21 RKO97084.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 RKO97084.1 - 0.11 12.4 0.2 0.53 10.1 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Rad17 PF03215.15 RKO97084.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_31 PF13614.6 RKO97084.1 - 0.19 11.6 0.0 0.71 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 RKO97084.1 - 0.2 11.8 0.0 14 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Mob1_phocein PF03637.17 RKO97085.1 - 6.8e-66 221.5 1.4 7.9e-66 221.2 1.4 1.0 1 0 0 1 1 1 1 Mob1/phocein family Arf PF00025.21 RKO97086.1 - 3.8e-78 260.9 0.1 4.4e-78 260.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 RKO97086.1 - 4.6e-17 62.1 0.0 5.3e-17 61.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO97086.1 - 1.1e-16 61.1 0.0 1.5e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RKO97086.1 - 7.7e-13 48.3 0.2 2.9e-08 33.3 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 RKO97086.1 - 1e-12 47.9 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RKO97086.1 - 7.9e-10 38.5 0.0 9.6e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKO97086.1 - 3.6e-06 27.1 0.0 5.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 RKO97086.1 - 3.9e-05 22.8 0.2 0.021 13.8 0.1 3.0 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 RKO97086.1 - 0.00025 21.0 0.1 0.042 13.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase cobW PF02492.19 RKO97086.1 - 0.0011 18.6 0.3 0.25 10.9 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 RKO97086.1 - 0.0018 17.8 0.1 0.017 14.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 RKO97086.1 - 0.0047 17.5 0.0 0.0078 16.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain NOG1 PF06858.14 RKO97086.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) ABC_tran PF00005.27 RKO97086.1 - 0.062 13.8 0.4 0.12 12.9 0.4 1.7 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 RKO97086.1 - 0.092 12.4 0.2 0.63 9.6 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 RKO97086.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RKO97086.1 - 0.22 11.8 0.8 1.4 9.2 0.5 2.3 1 1 1 2 2 2 0 AAA domain CHCH PF06747.13 RKO97088.1 - 6.1e-05 23.0 5.2 7.2e-05 22.8 5.2 1.1 1 0 0 1 1 1 1 CHCH domain Ndufs5 PF10200.9 RKO97088.1 - 0.00038 20.7 0.2 0.00038 20.7 0.2 1.0 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.13 RKO97088.1 - 0.0093 16.3 1.6 0.016 15.5 1.5 1.5 1 1 1 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_S9 PF00380.19 RKO97089.1 - 6.4e-34 117.1 0.2 7.3e-34 116.9 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 NRDE-2 PF08424.10 RKO97091.1 - 1.3e-10 40.9 0.1 1.3e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 RKO97091.1 - 0.00076 20.1 3.3 33 5.7 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 RKO97091.1 - 0.44 10.5 6.3 1.2 9.1 0.0 3.8 4 2 1 5 5 5 0 Mad3/BUB1 homology region 1 RRM_1 PF00076.22 RKO97092.1 - 0.011 15.5 0.2 4.6 7.1 0.1 2.4 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PilZ PF07238.14 RKO97092.1 - 0.07 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 PilZ domain DUF1175 PF06672.11 RKO97092.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1175) SHIPPO-rpt PF07004.12 RKO97093.1 - 1.3e-06 29.0 30.6 0.86 10.6 0.0 8.1 8 0 0 8 8 8 6 Sperm-tail PG-rich repeat Gag_p19 PF02228.16 RKO97093.1 - 0.035 14.6 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 Major core protein p19 Arf PF00025.21 RKO97094.1 - 9.4e-68 227.1 0.0 1.1e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 RKO97094.1 - 2.6e-12 47.0 0.0 3.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 RKO97094.1 - 2.2e-09 36.9 0.1 0.00023 20.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 RKO97094.1 - 8.1e-09 35.3 0.0 9.9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 RKO97094.1 - 2.5e-08 33.6 0.0 3.5e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RKO97094.1 - 4.1e-08 32.9 0.0 5.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKO97094.1 - 1.8e-07 31.2 0.0 2.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 RKO97094.1 - 0.00089 19.5 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 RKO97094.1 - 0.0013 18.4 0.0 0.065 12.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 RKO97094.1 - 0.0062 16.5 0.3 0.072 13.0 0.3 2.0 1 1 0 1 1 1 1 NACHT domain MeaB PF03308.16 RKO97094.1 - 0.011 14.7 0.0 0.07 12.1 0.0 2.1 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 RKO97094.1 - 0.024 14.2 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TniB PF05621.11 RKO97094.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_18 PF13238.6 RKO97094.1 - 0.12 13.0 0.0 0.2 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Tim17 PF02466.19 RKO97095.1 - 0.039 14.3 0.0 0.55 10.6 0.0 2.4 1 1 1 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 RKO97095.1 - 0.71 9.8 3.0 21 5.1 0.1 2.9 2 1 1 3 3 3 0 Mitochondrial carrier protein M16C_assoc PF08367.11 RKO97096.1 - 1.3e-41 142.4 0.0 2.1e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 RKO97096.1 - 1.2e-27 97.1 0.0 3.4e-20 72.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 RKO97096.1 - 0.001 19.1 0.0 0.0043 17.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) ATP-synt_Z PF16594.5 RKO97096.1 - 0.29 10.7 1.0 0.66 9.5 1.0 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated AAA PF00004.29 RKO97097.1 - 2.1e-94 312.9 0.0 7.1e-46 155.9 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO97097.1 - 3e-22 78.2 6.4 5.8e-11 42.0 0.9 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 RKO97097.1 - 1.5e-17 63.5 0.9 4.4e-17 62.0 0.2 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 RKO97097.1 - 9.8e-14 51.4 0.1 2.6e-05 24.0 0.0 3.1 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RKO97097.1 - 2.4e-13 50.6 0.0 7.7e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 RKO97097.1 - 1.4e-11 44.7 0.0 2.2e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 RKO97097.1 - 1.7e-11 44.3 0.1 3.4e-05 23.9 0.1 3.4 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO97097.1 - 3.6e-11 43.7 1.5 0.00056 20.3 0.0 4.8 3 2 0 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 RKO97097.1 - 1.5e-09 37.5 0.0 3.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.6 RKO97097.1 - 8.7e-09 35.8 0.3 0.062 13.6 0.1 4.1 2 2 1 3 3 2 2 AAA domain TIP49 PF06068.13 RKO97097.1 - 2.2e-08 33.7 0.0 0.00093 18.5 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 RKO97097.1 - 2.2e-07 30.8 1.1 1e-05 25.5 0.0 2.9 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 RKO97097.1 - 3e-07 30.0 0.2 0.022 14.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 RKO97097.1 - 4.5e-07 29.8 0.1 0.044 13.5 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein RNA_helicase PF00910.22 RKO97097.1 - 8.9e-07 29.3 0.0 0.0079 16.6 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 RKO97097.1 - 1e-06 28.8 0.0 0.048 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 RKO97097.1 - 2.1e-06 28.3 0.0 0.1 13.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 RKO97097.1 - 3.2e-06 27.5 0.2 0.075 13.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 RKO97097.1 - 5e-06 27.1 0.0 0.014 15.9 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.18 RKO97097.1 - 6.6e-06 26.1 0.0 0.076 12.8 0.0 2.8 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_7 PF12775.7 RKO97097.1 - 1.4e-05 24.7 0.0 0.067 12.7 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Parvo_NS1 PF01057.17 RKO97097.1 - 2.1e-05 23.8 0.1 0.036 13.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 RKO97097.1 - 3e-05 24.5 0.2 0.75 10.2 0.0 3.6 4 0 0 4 4 3 2 AAA domain ATPase PF06745.13 RKO97097.1 - 3.5e-05 23.3 1.1 2.2 7.6 0.0 3.9 4 0 0 4 4 4 2 KaiC AAA_25 PF13481.6 RKO97097.1 - 5.4e-05 22.8 2.5 1.6 8.3 0.0 4.0 2 2 1 4 4 4 1 AAA domain Viral_helicase1 PF01443.18 RKO97097.1 - 6.2e-05 22.8 0.0 0.0029 17.4 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 RKO97097.1 - 0.00017 21.3 0.0 0.86 9.3 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 RKO97097.1 - 0.00027 20.9 0.1 0.21 11.5 0.0 3.1 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea TsaE PF02367.17 RKO97097.1 - 0.00032 20.7 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 RKO97097.1 - 0.00035 20.1 0.1 0.66 9.4 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF815 PF05673.13 RKO97097.1 - 0.00049 19.4 0.0 0.077 12.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 RKO97097.1 - 0.00066 19.0 0.0 0.89 8.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_24 PF13479.6 RKO97097.1 - 0.0007 19.4 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 RKO97097.1 - 0.0011 18.9 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RKO97097.1 - 0.0011 18.9 0.1 0.23 11.4 0.0 3.1 3 0 0 3 3 3 1 NACHT domain ResIII PF04851.15 RKO97097.1 - 0.0012 18.9 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 RKO97097.1 - 0.0013 18.0 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain DUF2075 PF09848.9 RKO97097.1 - 0.0016 17.8 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 RKO97097.1 - 0.0055 16.5 0.0 4.1 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 RKO97097.1 - 0.0067 16.5 0.0 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 RKO97097.1 - 0.0076 16.2 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_19 PF13245.6 RKO97097.1 - 0.015 15.7 1.8 10 6.4 0.2 3.5 3 1 1 4 4 3 0 AAA domain NTPase_1 PF03266.15 RKO97097.1 - 0.018 15.0 0.4 3.2 7.6 0.0 3.3 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.6 RKO97097.1 - 0.041 13.6 0.1 7.7 6.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 RKO97097.1 - 0.067 12.9 0.0 16 5.1 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase SKI PF01202.22 RKO97097.1 - 0.069 13.3 0.0 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase PduV-EutP PF10662.9 RKO97097.1 - 0.1 12.3 0.0 3.5 7.4 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation UFD1 PF03152.14 RKO97097.1 - 0.17 11.4 0.0 0.98 8.9 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 S4 PF01479.25 RKO97098.1 - 1.4e-12 47.1 0.1 4.8e-12 45.4 0.0 2.0 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 RKO97098.1 - 2.2e-09 38.1 0.7 3.2e-09 37.6 0.4 1.5 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Actin PF00022.19 RKO97099.1 - 1.1e-113 380.0 0.0 8.8e-113 377.0 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 RKO97099.1 - 0.024 13.4 0.0 0.064 12.1 0.0 1.6 1 1 0 1 1 1 0 MreB/Mbl protein UCH PF00443.29 RKO97100.1 - 1.6e-52 178.6 0.0 1.9e-52 178.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 RKO97100.1 - 1e-12 48.3 0.2 3.8e-12 46.4 0.2 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 RKO97100.1 - 1.5e-10 40.6 0.6 4.4e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family PNP_UDP_1 PF01048.20 RKO97100.1 - 0.067 12.4 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphorylase superfamily IFT81_CH PF18383.1 RKO97100.1 - 0.11 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain SLX9 PF15341.6 RKO97101.1 - 1e-07 32.4 1.3 2.1e-07 31.4 1.3 1.5 1 1 0 1 1 1 1 Ribosome biogenesis protein SLX9 HECT PF00632.25 RKO97102.1 - 3.9e-79 266.3 0.0 4.3e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3493 PF11998.8 RKO97102.1 - 0.19 11.9 0.0 0.4 10.9 0.0 1.4 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 DAGAT PF03982.13 RKO97103.1 - 4.8e-100 334.3 0.0 5.7e-100 334.1 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase RNB PF00773.19 RKO97105.1 - 2.3e-39 135.6 0.0 6.7e-39 134.1 0.0 1.7 1 1 0 1 1 1 1 RNB domain ABC_tran PF00005.27 RKO97107.1 - 2.4e-14 54.0 0.0 3.5e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 RKO97107.1 - 0.03 14.7 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 RKO97107.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 RKO97107.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 RKO97107.1 - 0.13 12.8 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.23 RKO97108.1 - 1.9e-118 395.2 0.0 2.1e-118 395.0 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO97108.1 - 3e-26 92.1 0.0 4.8e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding PIF1 PF05970.14 RKO97108.1 - 0.006 15.8 0.2 0.011 15.0 0.2 1.3 1 0 0 1 1 1 1 PIF1-like helicase Kinesin_assoc PF16183.5 RKO97108.1 - 0.017 15.3 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 Kinesin-associated FlxA PF14282.6 RKO97108.1 - 0.032 14.2 0.5 0.067 13.2 0.5 1.5 1 0 0 1 1 1 0 FlxA-like protein AAA_22 PF13401.6 RKO97108.1 - 0.041 14.2 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain BST2 PF16716.5 RKO97108.1 - 0.13 12.9 0.3 0.28 11.8 0.3 1.5 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 Kp4 PF09044.10 RKO97109.1 - 5.9e-17 61.9 0.8 5.9e-17 61.9 0.8 1.7 2 0 0 2 2 2 1 Kp4 Helicase_C PF00271.31 RKO97110.1 - 2.4e-25 89.0 0.1 4e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 RKO97110.1 - 5.2e-10 39.4 0.2 2.2e-08 34.1 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 RKO97110.1 - 0.085 11.6 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain ThiC_Rad_SAM PF01964.18 RKO97110.1 - 0.093 11.5 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Radical SAM ThiC family SET PF00856.28 RKO97112.1 - 0.0012 19.3 0.0 0.0023 18.3 0.0 1.6 1 1 0 1 1 1 1 SET domain HMG_box PF00505.19 RKO97114.1 - 5.2e-13 49.2 0.1 5.8e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box CHDNT PF08073.12 RKO97114.1 - 0.0036 17.2 0.0 0.0061 16.5 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain MATalpha_HMGbox PF04769.12 RKO97114.1 - 0.027 13.8 0.0 0.031 13.6 0.0 1.1 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box CDH-cyt PF16010.5 RKO97115.1 - 3.3e-11 43.2 1.0 5e-11 42.6 1.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 RKO97115.1 - 7.4e-09 35.8 10.7 7.4e-09 35.8 10.7 2.3 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 RKO97115.1 - 9e-09 35.6 0.2 1.6e-08 34.8 0.2 1.4 1 0 0 1 1 1 1 DOMON domain DUF3169 PF11368.8 RKO97115.1 - 0.61 9.6 9.0 0.075 12.5 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF2427 PF10348.9 RKO97115.1 - 3 7.7 14.3 5.2 6.9 9.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF4271 PF14093.6 RKO97115.1 - 3.4 7.5 8.7 4.2 7.2 7.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) DUF202 PF02656.15 RKO97115.1 - 8.8 6.8 14.9 1.8e+04 -4.5 14.6 3.8 1 1 0 1 1 1 0 Domain of unknown function (DUF202) YqaJ PF09588.10 RKO97116.1 - 5.3e-18 65.6 0.0 1.1e-16 61.4 0.0 2.3 2 0 0 2 2 2 1 YqaJ-like viral recombinase domain DFRP_C PF16543.5 RKO97117.1 - 2.7e-23 82.3 0.8 2.7e-23 82.3 0.8 3.8 4 1 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 RKO97117.1 - 8.7e-08 31.9 1.1 8.7e-08 31.9 1.1 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 RKO97117.1 - 1.4e-06 29.0 14.9 0.00033 21.3 4.0 4.1 2 1 1 3 3 3 2 Torus domain zf_CCCH_4 PF18345.1 RKO97117.1 - 1.2e-05 25.2 7.7 1.2e-05 25.2 7.7 3.3 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 RKO97117.1 - 0.00014 21.6 10.0 0.00042 20.0 2.4 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 RKO97117.1 - 0.0054 16.9 1.0 0.12 12.6 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 RKO97117.1 - 0.009 16.5 12.5 0.029 14.8 4.9 2.9 2 1 0 2 2 2 1 RNA-binding, Nab2-type zinc finger DUF1178 PF06676.11 RKO97117.1 - 4.4 7.7 16.3 1.6 9.1 5.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1178) Peptidase_M20 PF01546.28 RKO97118.1 - 2.7e-34 118.7 0.0 2.4e-33 115.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 RKO97118.1 - 7.1e-09 35.6 0.0 2.6e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 RKO97118.1 - 0.09 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 DUF2939 PF11159.8 RKO97118.1 - 0.12 12.8 0.2 0.54 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) MFS_1 PF07690.16 RKO97119.1 - 8.9e-06 24.9 1.3 9.9e-06 24.7 1.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Mito_fiss_reg PF05308.11 RKO97120.1 - 0.016 15.3 2.9 0.02 15.0 0.9 2.0 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF4140 PF13600.6 RKO97120.1 - 0.19 12.2 1.8 6.5 7.3 0.2 2.3 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LPP PF04728.13 RKO97120.1 - 0.74 10.3 5.4 9.9 6.6 0.1 2.8 3 0 0 3 3 3 0 Lipoprotein leucine-zipper WPP PF13943.6 RKO97120.1 - 1.1 9.7 3.8 5.1 7.6 0.5 2.5 2 0 0 2 2 2 0 WPP domain CAP_N PF01213.19 RKO97120.1 - 1.2 8.5 12.0 0.077 12.5 6.9 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 RKO97120.1 - 1.3 9.0 12.3 3.1 7.9 12.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 SMN PF06003.12 RKO97120.1 - 2 7.6 7.5 3.7 6.7 7.5 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) C2 PF00168.30 RKO97121.1 - 1e-21 77.2 0.0 4.9e-08 33.2 0.0 3.6 3 0 0 3 3 3 3 C2 domain Membr_traf_MHD PF10540.9 RKO97121.1 - 2.5e-12 47.2 0.5 8.9e-05 22.7 0.0 2.8 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 RKO97121.1 - 0.011 14.3 0.8 0.019 13.5 0.8 1.3 1 0 0 1 1 1 0 Plant family of unknown function (DUF810) Synaptobrevin PF00957.21 RKO97122.1 - 0.12 12.2 1.4 0.41 10.5 1.4 1.9 1 0 0 1 1 1 0 Synaptobrevin DUF4538 PF15061.6 RKO97122.1 - 0.28 10.9 5.3 0.16 11.8 2.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) Tmemb_9 PF05434.11 RKO97123.1 - 7.8 6.4 5.2 36 4.2 0.2 2.7 3 0 0 3 3 3 0 TMEM9 LPMO_10 PF03067.15 RKO97125.1 - 3.2e-08 34.5 8.4 3.8e-08 34.2 0.5 3.4 2 2 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading IF4E PF01652.18 RKO97126.1 - 2.1e-49 167.4 0.3 2.6e-49 167.0 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E KAP PF05804.12 RKO97126.1 - 0.21 9.7 0.0 0.27 9.3 0.0 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) WD40 PF00400.32 RKO97127.1 - 6.5e-16 58.4 10.0 3.2e-05 24.6 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat NLE PF08154.12 RKO97127.1 - 1e-15 58.0 0.1 1.8e-15 57.2 0.1 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 RKO97127.1 - 4.8e-06 26.8 0.0 0.23 11.8 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO97127.1 - 0.015 13.9 0.7 0.24 10.0 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Trm112p PF03966.16 RKO97128.1 - 1.2e-16 61.0 0.0 1.7e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein VWA_2 PF13519.6 RKO97129.1 - 1.3e-10 41.8 0.0 6.7e-10 39.6 0.0 2.2 2 2 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 RKO97129.1 - 6.9e-10 39.4 0.0 5e-09 36.6 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 RKO97129.1 - 0.025 13.9 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein SNAP-25 PF00835.19 RKO97129.1 - 0.032 14.5 0.1 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 SNAP-25 family Pkinase PF00069.25 RKO97130.1 - 3.6e-56 190.4 0.0 4.6e-56 190.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97130.1 - 1.3e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 RKO97130.1 - 0.0088 15.7 0.2 0.018 14.6 0.2 1.5 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 RKO97130.1 - 0.021 14.2 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 RKO97130.1 - 0.035 13.4 2.0 0.12 11.7 0.4 2.4 2 1 0 2 2 2 0 Kinase-like Ral PF11058.8 RKO97130.1 - 0.039 13.5 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Antirestriction protein Ral FTA2 PF13095.6 RKO97130.1 - 0.1 12.2 0.1 0.58 9.7 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKO97130.1 - 0.14 12.1 0.1 0.59 10.0 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family MTCP1 PF08991.10 RKO97135.1 - 3.9e-13 49.4 6.0 4.8e-13 49.1 6.0 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 RKO97135.1 - 0.0012 18.9 6.1 0.0012 18.9 6.1 1.5 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.10 RKO97135.1 - 0.97 9.5 9.5 0.82 9.7 4.2 2.7 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Y_phosphatase2 PF03162.13 RKO97136.1 - 1.3e-37 128.9 0.0 1.6e-37 128.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RKO97136.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family DUF442 PF04273.13 RKO97136.1 - 0.07 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) PS_Dcarbxylase PF02666.15 RKO97137.1 - 7.5e-71 237.8 0.0 3.1e-69 232.5 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase fn3_3 PF14686.6 RKO97137.1 - 0.056 13.2 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II Peptidase_S10 PF00450.22 RKO97138.1 - 1.4e-61 209.2 0.8 9e-61 206.5 0.8 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase AAA PF00004.29 RKO97139.1 - 2.7e-38 131.4 0.0 1.1e-37 129.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 RKO97139.1 - 7e-11 42.0 0.0 2.8e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 RKO97139.1 - 1e-10 41.2 0.2 6.2e-10 38.7 0.2 2.4 1 1 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 RKO97139.1 - 1e-06 28.6 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 RKO97139.1 - 0.00012 22.2 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RKO97139.1 - 0.00042 20.3 0.1 0.0022 18.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKO97139.1 - 0.0011 19.3 0.1 0.0031 17.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 RKO97139.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 RKO97139.1 - 0.002 18.5 0.0 0.0036 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 RKO97139.1 - 0.0023 18.1 0.1 0.0039 17.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RKO97139.1 - 0.003 17.0 0.1 0.0059 16.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 RKO97139.1 - 0.005 17.4 0.3 0.034 14.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 RKO97139.1 - 0.0058 16.4 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 RKO97139.1 - 0.0088 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 RKO97139.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 RKO97139.1 - 0.015 15.6 0.0 0.027 14.9 0.0 1.6 1 1 0 1 1 1 0 RNA helicase ATPase PF06745.13 RKO97139.1 - 0.023 14.0 0.1 0.55 9.5 0.0 2.3 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 RKO97139.1 - 0.026 14.0 0.1 0.07 12.6 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 RKO97139.1 - 0.03 14.6 0.0 0.096 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 RKO97139.1 - 0.056 12.9 0.1 0.096 12.1 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.6 RKO97139.1 - 0.057 13.9 0.1 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 RKO97139.1 - 0.089 12.0 0.0 0.34 10.1 0.0 1.8 1 1 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 RKO97139.1 - 0.092 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 RKO97139.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 RKO97139.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 RKO97139.1 - 0.11 12.1 0.2 0.7 9.4 0.2 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RKO97139.1 - 0.13 11.9 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 RKO97139.1 - 0.14 12.0 0.0 0.57 10.1 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Cyclin PF08613.11 RKO97140.1 - 2.4e-29 102.8 0.1 2.7e-29 102.6 0.1 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 RKO97140.1 - 0.00083 19.1 0.2 0.00099 18.9 0.2 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Phage_GPD PF05954.11 RKO97141.1 - 0.02 14.2 0.7 0.049 12.9 0.0 1.9 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) Med11 PF10280.9 RKO97142.1 - 0.0002 21.9 2.6 0.00028 21.3 2.6 1.3 1 0 0 1 1 1 1 Mediator complex protein ALIX_LYPXL_bnd PF13949.6 RKO97142.1 - 0.019 14.3 3.8 0.026 13.8 1.0 1.9 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV HLH PF00010.26 RKO97145.1 - 1.6e-11 43.9 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Hydrophobin PF01185.18 RKO97146.1 - 2.7e-09 37.5 9.7 4.1e-09 36.9 9.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin DUF4633 PF15464.6 RKO97147.1 - 0.031 14.4 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) F-box PF00646.33 RKO97147.1 - 0.076 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 F-box domain Thg1 PF04446.12 RKO97152.1 - 1.5e-28 99.3 0.0 2.1e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase WD40 PF00400.32 RKO97155.1 - 2e-27 94.9 18.4 2.5e-05 24.9 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97155.1 - 4.4e-11 42.9 0.5 0.013 15.8 0.0 4.7 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 RKO97155.1 - 0.038 13.6 0.9 1 8.9 0.2 2.5 1 1 1 2 2 2 0 PQQ-like domain Radial_spoke PF04712.12 RKO97157.1 - 1.6e-133 446.3 0.1 1.9e-133 446.0 0.1 1.1 1 0 0 1 1 1 1 Radial spokehead-like protein PAS_4 PF08448.10 RKO97157.1 - 0.57 10.5 3.8 11 6.3 0.0 3.8 3 1 0 3 3 3 0 PAS fold Frag1 PF10277.9 RKO97158.1 - 1.6e-33 116.1 6.9 1.6e-33 116.1 6.9 2.5 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family Aminotran_1_2 PF00155.21 RKO97159.1 - 1.3e-32 113.4 0.0 1.8e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RKO97159.1 - 0.00097 18.5 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase L51_S25_CI-B8 PF05047.16 RKO97160.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Acetyltransf_1 PF00583.25 RKO97161.1 - 1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 RKO97161.1 - 8.8e-08 32.5 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKO97161.1 - 6.2e-07 29.4 0.0 7.3e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKO97161.1 - 2.8e-06 27.2 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 RKO97161.1 - 0.0017 18.5 0.1 0.0022 18.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 RKO97161.1 - 0.0032 17.5 0.1 0.0055 16.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RKO97161.1 - 0.0097 15.6 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyoxalase_3 PF13468.6 RKO97161.1 - 0.037 14.1 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Acetyltransf_6 PF13480.7 RKO97161.1 - 0.087 13.0 1.2 0.25 11.5 0.9 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain E1_dh PF00676.20 RKO97163.1 - 2.6e-108 361.5 0.1 3.2e-108 361.2 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 RKO97163.1 - 0.0017 17.6 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Asp PF00026.23 RKO97164.1 - 2.6e-66 224.2 0.1 2.9e-66 224.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RKO97164.1 - 1.1e-13 51.9 0.3 5.4e-11 43.0 0.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 RKO97164.1 - 8.6e-07 28.9 0.1 2.5e-05 24.1 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal SKG6 PF08693.10 RKO97165.1 - 4.9 6.6 6.5 11 5.5 6.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Lum_binding PF00677.17 RKO97166.1 - 3.9e-37 126.1 0.0 1.3e-18 66.8 0.1 2.3 2 0 0 2 2 2 2 Lumazine binding domain Hydrophobin PF01185.18 RKO97167.1 - 2.4e-07 31.3 11.0 3.4e-07 30.8 11.0 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Inositol_P PF00459.25 RKO97168.1 - 1.8e-49 168.7 0.0 2e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Annexin PF00191.20 RKO97169.1 - 3.7e-79 260.7 0.2 1.3e-23 82.8 0.0 4.1 4 0 0 4 4 4 4 Annexin Abhydrolase_2 PF02230.16 RKO97170.1 - 4.8e-66 222.7 0.0 5.4e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 RKO97170.1 - 3.3e-09 36.4 0.1 5.2e-06 25.9 0.0 3.0 2 1 1 3 3 3 3 Serine aminopeptidase, S33 FSH1 PF03959.13 RKO97170.1 - 1.7e-07 31.1 0.0 7.1e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 RKO97170.1 - 4e-06 26.5 0.0 0.00017 21.1 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 RKO97170.1 - 1.4e-05 24.8 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 RKO97170.1 - 2.5e-05 25.0 4.3 9.8e-05 23.1 2.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 RKO97170.1 - 0.00096 19.1 0.0 0.15 11.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Cutinase PF01083.22 RKO97170.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase zf-RING_2 PF13639.6 RKO97171.1 - 4.1e-16 59.0 8.6 5.2e-16 58.7 8.6 1.1 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 RKO97171.1 - 3e-12 46.0 2.3 3e-12 46.0 2.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 RKO97171.1 - 2.3e-11 43.4 7.0 3e-11 43.0 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO97171.1 - 2.4e-09 37.1 2.0 2.4e-09 37.1 2.0 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RKO97171.1 - 5.7e-09 36.1 9.7 1.7e-08 34.6 9.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKO97171.1 - 9.3e-09 35.1 6.0 1.2e-08 34.8 6.0 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 RKO97171.1 - 1.4e-08 34.5 7.4 1.9e-08 34.1 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 RKO97171.1 - 2.4e-07 30.5 6.1 3.1e-07 30.2 6.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKO97171.1 - 4.2e-05 23.3 5.2 6.2e-05 22.8 5.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 RKO97171.1 - 0.00011 21.7 5.4 0.00017 21.1 5.4 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type RINGv PF12906.7 RKO97171.1 - 0.00023 21.2 5.3 0.00052 20.1 5.3 1.6 1 1 0 1 1 1 1 RING-variant domain zf-ANAPC11 PF12861.7 RKO97171.1 - 0.0012 18.9 8.1 0.0082 16.2 8.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 RKO97171.1 - 0.0046 17.2 5.2 0.0064 16.8 5.2 1.2 1 0 0 1 1 1 1 RING-like domain Zf_RING PF16744.5 RKO97171.1 - 0.0071 16.4 3.1 0.0071 16.4 3.1 1.4 1 1 0 1 1 1 1 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 RKO97171.1 - 0.019 15.1 5.3 0.057 13.6 5.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.29 RKO97171.1 - 0.038 13.9 4.6 0.067 13.1 4.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 RKO97171.1 - 0.044 13.6 5.1 0.064 13.1 5.1 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 RKO97171.1 - 0.085 12.7 2.3 0.13 12.2 2.3 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_RING PF05883.11 RKO97171.1 - 0.1 12.6 0.6 0.13 12.2 0.6 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.6 RKO97171.1 - 0.18 11.7 3.8 0.34 10.7 3.8 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 RKO97171.1 - 0.91 9.7 9.2 4.2 7.6 9.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain VWA_2 PF13519.6 RKO97172.1 - 0.04 14.6 0.0 0.088 13.5 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain NOA36 PF06524.12 RKO97172.1 - 0.82 8.9 17.8 1.3 8.3 17.8 1.2 1 0 0 1 1 1 0 NOA36 protein tRNA-synt_2 PF00152.20 RKO97173.1 - 4.1e-77 259.3 0.0 5.5e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 RKO97173.1 - 8.9e-10 38.4 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 RKO97173.1 - 2.3e-09 37.1 0.1 0.00036 20.1 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) ASH PF15780.5 RKO97173.1 - 0.038 14.2 0.1 0.067 13.4 0.1 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Mpp10 PF04006.12 RKO97173.1 - 1.1 7.6 11.6 1.6 7.1 11.6 1.1 1 0 0 1 1 1 0 Mpp10 protein Ribosomal_L2_C PF03947.18 RKO97174.1 - 1.5e-42 144.8 1.6 1.5e-42 144.8 1.6 2.6 3 0 0 3 3 3 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 RKO97174.1 - 8.5e-18 64.1 0.2 8.5e-18 64.1 0.2 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Mre11_DNA_bind PF04152.14 RKO97175.1 - 7.2e-41 140.3 0.0 1.1e-40 139.8 0.0 1.3 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 RKO97175.1 - 1.3e-13 51.9 2.1 3e-13 50.7 2.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 RKO97175.1 - 5.2e-06 26.8 0.7 6.3e-05 23.2 0.7 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Crp PF00325.20 RKO97175.1 - 0.029 14.0 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family SBDS PF01172.18 RKO97176.1 - 0.057 13.5 0.1 0.38 10.9 0.1 2.1 1 1 0 1 1 1 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Myb_DNA-binding PF00249.31 RKO97177.1 - 4.4e-22 78.0 3.6 7.8e-11 42.0 1.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKO97177.1 - 1e-20 73.7 4.6 3.1e-12 46.6 2.1 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 RKO97177.1 - 0.011 15.8 0.1 0.54 10.3 0.0 2.6 1 1 1 2 2 2 0 SLIDE HTH_AsnC-type PF13404.6 RKO97177.1 - 0.02 14.7 0.0 0.05 13.4 0.0 1.8 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Rap1_C PF11626.8 RKO97177.1 - 0.027 14.6 0.0 0.28 11.3 0.1 2.3 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 RKO97177.1 - 0.066 13.1 0.0 2.7 7.9 0.1 2.5 2 0 0 2 2 2 0 Myb DNA-binding like Met_synt_B12 PF02965.17 RKO97177.1 - 0.32 10.4 2.2 0.24 10.9 0.1 1.7 2 0 0 2 2 2 0 Vitamin B12 dependent methionine synthase, activation domain FAM193_C PF15914.5 RKO97177.1 - 0.73 9.6 2.9 0.96 9.2 1.4 2.0 1 1 1 2 2 2 0 FAM193 family C-terminal SGP PF17228.2 RKO97178.1 - 0.022 15.6 18.1 0.043 14.7 18.1 1.5 1 0 0 1 1 1 0 Sulphur globule protein KRTAP PF11759.8 RKO97178.1 - 0.67 10.5 65.5 2.4 8.8 41.4 2.2 1 1 1 2 2 2 0 Keratin-associated matrix Vps62 PF06101.11 RKO97180.1 - 1.3e-15 56.7 1.4 2.4e-11 42.6 0.1 3.0 3 0 0 3 3 3 3 Vacuolar protein sorting-associated protein 62 Cyt_c_ox_IV PF12270.8 RKO97181.1 - 0.67 10.1 3.7 1 9.5 3.7 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Sensor PF13796.6 RKO97181.1 - 1.3 9.0 11.1 1.3 9.1 0.7 2.2 2 0 0 2 2 2 0 Putative sensor Phosphodiest PF01663.22 RKO97182.1 - 4.3e-11 43.0 1.1 4.3e-11 43.0 1.1 1.7 1 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 RKO97182.1 - 1.1e-05 24.9 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 RKO97182.1 - 0.0015 18.0 0.1 0.0026 17.2 0.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF2474 PF10617.9 RKO97182.1 - 0.099 12.5 3.7 0.19 11.6 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2474) PglZ PF08665.12 RKO97182.1 - 0.21 11.7 0.5 7.5 6.6 0.1 2.2 2 0 0 2 2 2 0 PglZ domain Hydrolase_4 PF12146.8 RKO97188.1 - 4.3e-27 94.9 0.0 2.4e-24 85.9 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 RKO97188.1 - 9.7e-12 45.1 0.1 1e-10 41.7 0.1 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 RKO97188.1 - 6.4e-08 32.5 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 RKO97188.1 - 4.6e-06 27.4 0.1 4.6e-06 27.4 0.1 2.7 2 1 0 3 3 3 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 RKO97188.1 - 0.018 14.6 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 RKO97188.1 - 0.051 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 RKO97188.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 RKO97188.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 RKO97188.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family RVT_1 PF00078.27 RKO97189.1 - 1.8e-05 24.4 0.0 1.9e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DSHCT PF08148.12 RKO97190.1 - 1.9e-46 157.7 0.7 3.1e-46 157.1 0.7 1.3 1 0 0 1 1 1 1 DSHCT (NUC185) domain Helicase_C PF00271.31 RKO97190.1 - 4.5e-06 27.0 0.0 1.7e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.6 RKO97190.1 - 0.0029 17.6 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 rRNA-processing arch domain RPN1_RPN2_N PF17781.1 RKO97191.1 - 1.9e-117 392.1 0.2 4.9e-117 390.7 0.0 1.7 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain PC_rep PF01851.22 RKO97191.1 - 2.4e-24 84.5 17.6 6e-07 29.6 0.1 8.1 8 0 0 8 8 8 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 RKO97191.1 - 1.2e-07 32.1 12.2 0.00046 20.5 1.7 6.2 5 2 2 7 7 7 3 HEAT repeats HEAT PF02985.22 RKO97191.1 - 0.043 14.1 1.1 1.5e+02 3.0 0.0 4.9 4 0 0 4 4 4 0 HEAT repeat Glyco_hydro_16 PF00722.21 RKO97192.1 - 6e-07 29.1 0.0 1.2e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ApbA_C PF08546.11 RKO97195.1 - 4.6e-26 91.5 0.0 1.1e-25 90.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 RKO97195.1 - 1.1e-25 90.0 0.0 1.8e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF543 PF04418.12 RKO97196.1 - 2.5e-21 75.4 1.5 2.7e-21 75.3 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Got1 PF04178.12 RKO97197.1 - 4.1e-31 107.7 16.0 6.1e-31 107.2 16.0 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family GTP_cyclohydroI PF01227.22 RKO97197.1 - 0.057 12.8 0.1 7.3 6.0 0.0 2.2 2 0 0 2 2 2 0 GTP cyclohydrolase I DUF3561 PF12084.8 RKO97197.1 - 0.85 9.7 12.9 3.6 7.7 12.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3561) Mon1 PF03164.14 RKO97199.1 - 0.2 10.7 0.5 0.56 9.2 0.1 1.7 2 0 0 2 2 2 0 Trafficking protein Mon1 Cytidylate_kin PF02224.18 RKO97201.1 - 4.5e-40 137.6 0.0 5.4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase AAA_33 PF13671.6 RKO97201.1 - 0.0034 17.6 0.0 0.0034 17.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 RKO97201.1 - 0.026 15.0 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.6 RKO97201.1 - 0.075 13.2 0.1 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_6 PF12774.7 RKO97201.1 - 0.19 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 RKO97201.1 - 0.2 12.2 0.0 0.51 10.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain PEPCK_ATP PF01293.20 RKO97203.1 - 5.2e-217 721.1 0.0 6.4e-217 720.8 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 RKO97203.1 - 0.047 14.1 0.0 0.092 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 RKO97203.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain HH_signal PF01085.18 RKO97204.1 - 0.018 14.7 0.2 0.037 13.7 0.2 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Serinc PF03348.15 RKO97206.1 - 2.9e-129 431.8 0.0 4.8e-129 431.0 0.0 1.3 1 1 0 1 1 1 1 Serine incorporator (Serinc) RmlD_sub_bind PF04321.17 RKO97207.1 - 1.5e-57 194.9 1.0 2.6e-57 194.1 1.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 RKO97207.1 - 5.7e-27 94.7 0.0 8.9e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 RKO97207.1 - 3.6e-12 46.3 0.1 1e-11 44.9 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 RKO97207.1 - 6e-12 45.3 0.6 1.9e-09 37.1 0.1 2.8 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 RKO97207.1 - 2.6e-09 36.5 0.0 4.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 RKO97207.1 - 3.2e-07 29.8 1.5 8.8e-05 21.8 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein Diphthamide_syn PF01866.17 RKO97209.1 - 1.4e-81 274.3 0.0 1.7e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein GDA1_CD39 PF01150.17 RKO97210.1 - 5.7e-92 308.6 0.0 7.1e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family RSN1_TM PF13967.6 RKO97211.1 - 3.7e-38 130.7 0.0 7.1e-38 129.8 0.0 1.5 1 1 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 RKO97211.1 - 4.3e-09 36.8 0.0 6.3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DEC-1_N PF04625.13 RKO97211.1 - 0.065 12.2 2.1 0.098 11.7 2.1 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region OsmC PF02566.19 RKO97212.1 - 5.2e-13 49.3 0.0 6.4e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 OsmC-like protein Swi3 PF07962.12 RKO97214.1 - 1.4e-16 60.2 0.0 2.1e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Methyltransf_28 PF02636.17 RKO97215.1 - 8.8e-64 215.6 0.0 1e-63 215.4 0.0 1.0 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_L28 PF00830.19 RKO97216.1 - 0.0012 18.9 0.1 0.0023 18.1 0.0 1.5 2 0 0 2 2 2 1 Ribosomal L28 family DUF2526 PF10735.9 RKO97216.1 - 0.16 12.2 0.0 0.23 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2526) Voltage_CLC PF00654.20 RKO97217.1 - 7.9e-81 272.0 30.5 6e-80 269.1 26.4 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CENP-B_dimeris PF09026.10 RKO97217.1 - 0.11 12.9 3.2 0.2 12.0 3.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.9 RKO97217.1 - 6.3 5.8 6.6 10 5.2 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Kinesin PF00225.23 RKO97218.1 - 1.3e-93 313.6 0.0 1.5e-93 313.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO97218.1 - 9.7e-19 67.8 0.0 1.5e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Ligase_CoA PF00549.19 RKO97219.1 - 8.1e-24 84.2 0.7 1.6e-23 83.2 0.7 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_2 PF08442.10 RKO97219.1 - 4.3e-16 59.1 0.2 2.9e-15 56.4 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain MFAP1 PF06991.11 RKO97221.1 - 3e-44 151.5 12.9 3e-44 151.5 12.9 1.5 1 1 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing AF-4 PF05110.13 RKO97221.1 - 0.28 9.2 19.1 0.04 12.0 15.4 1.4 1 1 0 1 1 1 0 AF-4 proto-oncoprotein Borrelia_P83 PF05262.11 RKO97221.1 - 1.9 6.9 9.5 2.3 6.6 9.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Sel1 PF08238.12 RKO97222.1 - 4.1e-97 316.4 53.0 4.7e-09 36.6 0.2 14.5 14 1 0 14 14 14 13 Sel1 repeat DUF1580 PF07618.11 RKO97222.1 - 0.074 12.7 0.4 6.7 6.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1580) TPR_16 PF13432.6 RKO97222.1 - 0.32 11.7 29.9 6.7 7.5 0.0 7.8 7 1 1 8 8 8 0 Tetratricopeptide repeat WD40 PF00400.32 RKO97225.1 - 3.2e-18 65.8 9.1 2.8e-06 27.9 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97225.1 - 2.9e-05 24.3 0.0 0.0044 17.3 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO97225.1 - 0.093 11.4 0.1 0.91 8.1 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Asp PF00026.23 RKO97226.1 - 1.9e-55 188.5 0.0 2.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 RKO97226.1 - 2.8e-07 31.0 0.0 0.0049 17.1 0.0 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 RKO97226.1 - 4.7e-05 23.9 0.3 0.016 15.8 0.0 3.3 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 RKO97226.1 - 0.016 14.9 0.2 0.052 13.3 0.0 1.9 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 RKO97226.1 - 0.052 14.1 0.2 21 5.7 0.0 3.2 2 2 0 2 2 2 0 gag-polyprotein putative aspartyl protease GrpE PF01025.19 RKO97227.1 - 3.8e-50 169.8 0.4 4.6e-50 169.5 0.4 1.2 1 0 0 1 1 1 1 GrpE DUF4407 PF14362.6 RKO97227.1 - 0.062 12.7 3.7 0.082 12.2 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Helicase_C PF00271.31 RKO97228.1 - 9.7e-13 48.4 0.0 1.6e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribosomal_L16 PF00252.18 RKO97229.1 - 1.2e-43 148.3 0.1 1.4e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e NIF PF03031.18 RKO97230.1 - 1.1e-11 44.7 0.0 1.3e-05 25.0 0.0 2.9 3 0 0 3 3 3 2 NLI interacting factor-like phosphatase eIF3m_C_helix PF18005.1 RKO97231.1 - 0.066 12.9 0.5 0.066 12.9 0.5 2.6 3 0 0 3 3 3 0 eIF3 subunit M, C-terminal helix Filament PF00038.21 RKO97231.1 - 0.083 12.5 37.6 0.0074 15.9 21.2 2.6 1 1 1 2 2 2 0 Intermediate filament protein Phage_GP20 PF06810.11 RKO97231.1 - 4.8 7.0 12.4 0.33 10.8 3.6 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Golgin_A5 PF09787.9 RKO97231.1 - 8.5 5.7 33.8 57 3.0 21.8 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 Methyltransf_12 PF08242.12 RKO97232.1 - 7.3e-19 68.4 0.0 2.4e-17 63.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 RKO97232.1 - 1.8e-16 60.4 0.0 3e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO97232.1 - 5.4e-15 55.9 0.0 1.7e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO97232.1 - 2.5e-12 47.3 0.0 6.3e-12 46.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO97232.1 - 7.8e-11 42.0 0.0 1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKO97232.1 - 2.2e-05 24.1 0.0 4.4e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 RKO97232.1 - 0.00038 19.7 0.0 0.00075 18.8 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 RKO97232.1 - 0.00082 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 RKO97232.1 - 0.03 14.2 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_4 PF02390.17 RKO97232.1 - 0.15 11.6 0.0 2.3 7.6 0.0 2.3 2 1 0 2 2 2 0 Putative methyltransferase NodS PF05401.11 RKO97232.1 - 0.17 11.5 0.0 0.48 10.0 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) Mhr1 PF12829.7 RKO97233.1 - 2.5e-08 33.9 0.3 4.9e-08 33.0 0.1 1.6 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination SPO22 PF08631.10 RKO97234.1 - 7.9e-12 45.2 3.5 7.9e-12 45.2 3.5 4.5 4 1 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 RKO97234.1 - 0.00015 22.3 6.6 1 10.3 0.2 4.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO97234.1 - 0.0024 18.5 5.6 0.01 16.5 1.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 RKO97234.1 - 0.048 14.2 6.7 0.59 10.7 0.6 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKO97234.1 - 0.31 11.3 4.7 0.17 12.2 1.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKO97234.1 - 0.89 9.8 6.3 0.73 10.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Arm PF00514.23 RKO97235.1 - 0.021 14.9 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat APS_kinase PF01583.20 RKO97235.1 - 0.049 13.5 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP PF05804.12 RKO97235.1 - 0.06 11.5 0.2 0.088 10.9 0.2 1.3 1 1 0 1 1 1 0 Kinesin-associated protein (KAP) VHS PF00790.19 RKO97236.1 - 1.8e-40 138.1 0.0 3.6e-40 137.1 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 RKO97236.1 - 7e-10 39.1 1.0 3.5e-09 36.9 0.0 2.7 3 0 0 3 3 3 1 GAT domain Nsp1_C PF05064.13 RKO97236.1 - 0.019 14.8 0.3 0.073 12.9 0.0 2.1 2 1 1 3 3 3 0 Nsp1-like C-terminal region KxDL PF10241.9 RKO97236.1 - 0.026 14.8 0.7 3.9 7.8 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein ISG65-75 PF11727.8 RKO97236.1 - 0.044 13.0 0.3 0.081 12.1 0.3 1.4 1 0 0 1 1 1 0 Invariant surface glycoprotein Hist_deacetyl PF00850.19 RKO97237.1 - 1.4e-83 280.9 0.0 1.8e-83 280.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Ribosomal_S10 PF00338.22 RKO97238.1 - 1.7e-17 63.4 0.0 1.9e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e NUC173 PF08161.12 RKO97239.1 - 2.4e-27 95.9 0.1 2.2e-26 92.8 0.0 2.6 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.22 RKO97239.1 - 0.013 15.7 2.5 1.4 9.4 0.0 4.4 3 0 0 3 3 3 0 HEAT repeat TAN PF11640.8 RKO97239.1 - 0.023 14.8 0.2 0.17 12.0 0.0 2.6 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair HAD_2 PF13419.6 RKO97240.1 - 6e-23 81.8 0.0 7.4e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RKO97240.1 - 3.1e-14 53.8 0.0 8e-13 49.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 RKO97240.1 - 1.5e-05 25.0 0.0 3.4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 RKO97240.1 - 2.9e-05 24.1 0.0 0.059 13.5 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 RKO97240.1 - 0.00014 22.3 0.0 0.00018 22.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF5016 PF16408.5 RKO97240.1 - 0.1 12.6 0.1 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5016) Syntaxin PF00804.25 RKO97242.1 - 4.3e-43 147.3 14.6 4.3e-43 147.3 14.6 1.7 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 RKO97242.1 - 4.8e-13 48.9 2.0 1e-12 47.8 2.0 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 RKO97242.1 - 1.5e-07 31.7 8.1 1.5e-07 31.7 8.1 2.6 2 1 0 2 2 2 1 Syntaxin-like protein PAH PF02671.21 RKO97242.1 - 0.019 15.1 0.1 0.036 14.2 0.1 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat VitD-bind_III PF09164.10 RKO97242.1 - 0.15 12.1 0.1 0.15 12.1 0.1 2.4 3 0 0 3 3 3 0 Vitamin D binding protein, domain III TraG_N PF07916.11 RKO97242.1 - 2.1 7.1 7.9 2.7 6.7 2.9 2.0 2 0 0 2 2 2 0 TraG-like protein, N-terminal region Syntaxin-6_N PF09177.11 RKO97242.1 - 2.2 8.9 8.6 5.4 7.6 3.3 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 RKO97242.1 - 2.2 8.3 9.8 0.51 10.4 1.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.6 RKO97242.1 - 2.6 6.6 17.4 0.24 10.0 11.3 1.9 2 0 0 2 2 2 0 AAA domain WXG100 PF06013.12 RKO97242.1 - 2.7 8.3 17.8 1.2 9.4 1.2 4.6 4 1 0 5 5 5 0 Proteins of 100 residues with WXG Peptidase_S46 PF10459.9 RKO97242.1 - 4.8 5.7 15.8 7.4 5.1 15.8 1.3 1 1 0 1 1 1 0 Peptidase S46 U3_assoc_6 PF08640.11 RKO97243.1 - 2.1e-27 95.0 1.0 2.4e-26 91.6 0.2 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 RKO97243.1 - 2e-06 28.1 1.0 0.0027 18.4 0.3 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat KIX_2 PF16987.5 RKO97243.1 - 0.084 12.9 0.3 0.2 11.7 0.3 1.6 1 0 0 1 1 1 0 KIX domain Tctex-1 PF03645.13 RKO97245.1 - 3.5e-22 78.6 0.0 4.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family GRIP PF01465.20 RKO97247.1 - 5e-11 42.3 0.6 1e-09 38.2 0.6 2.4 1 1 0 1 1 1 1 GRIP domain DUF3138 PF11336.8 RKO97247.1 - 1.9 7.0 6.9 3.7 6.0 6.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) Catalase PF00199.19 RKO97248.1 - 4.2e-177 589.0 0.1 5.4e-177 588.6 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 RKO97248.1 - 1.6e-19 69.9 0.0 2.8e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 RKO97248.1 - 1.6e-12 47.3 0.0 2.4e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 RKO97248.1 - 7.6e-11 42.1 0.0 1.3e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family PIN PF01850.21 RKO97249.1 - 0.12 12.8 0.0 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 PIN domain CK_II_beta PF01214.18 RKO97250.1 - 3e-69 232.5 0.0 3.3e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit HscB_4_cys PF18256.1 RKO97250.1 - 0.14 11.9 5.3 2.5 8.0 0.1 2.8 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Tetraspanin PF00335.20 RKO97251.1 - 5.1e-12 46.0 10.3 9e-12 45.2 10.3 1.3 1 1 0 1 1 1 1 Tetraspanin family MRAP PF15183.6 RKO97251.1 - 1.1 9.2 3.1 3.6 7.6 0.0 2.8 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family Tyrosinase PF00264.20 RKO97252.1 - 5.8e-37 128.1 8.6 1.7e-36 126.6 8.6 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase ABC_membrane PF00664.23 RKO97254.1 - 6.2e-39 134.3 5.0 8.8e-39 133.8 5.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 RKO97254.1 - 2.8e-34 118.6 0.0 4.5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 RKO97254.1 - 1.4e-06 28.0 0.0 0.00081 18.9 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 RKO97254.1 - 0.0007 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.9 RKO97254.1 - 0.0032 16.3 0.1 0.0082 15.0 0.0 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_15 PF13175.6 RKO97254.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_16 PF13191.6 RKO97254.1 - 0.023 15.1 0.2 0.062 13.7 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 RKO97254.1 - 0.029 14.5 0.1 0.062 13.4 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain RsgA_GTPase PF03193.16 RKO97254.1 - 0.031 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 RKO97254.1 - 0.043 13.8 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKO97254.1 - 0.053 13.8 0.2 0.58 10.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 RKO97254.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DFP PF04127.15 RKO97255.1 - 1.3e-19 70.8 0.0 1.1e-09 38.4 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein TPR_2 PF07719.17 RKO97256.1 - 8.5e-19 66.1 8.4 0.00029 20.7 0.1 8.1 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 RKO97256.1 - 9.1e-13 47.9 8.2 0.16 12.9 0.0 7.4 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 RKO97256.1 - 1.1e-11 44.3 0.2 0.00081 19.6 0.0 5.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKO97256.1 - 5.4e-10 38.7 3.9 0.015 15.1 0.0 6.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 RKO97256.1 - 1.2e-09 37.6 0.3 0.091 13.0 0.0 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 RKO97256.1 - 4.4e-09 36.7 1.9 0.0017 18.9 0.2 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 RKO97256.1 - 1.4e-08 35.3 6.6 0.014 16.0 0.7 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO97256.1 - 1.8e-07 31.3 0.5 0.049 13.9 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 RKO97256.1 - 1.4e-06 27.9 0.0 0.2 11.3 0.0 4.1 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.6 RKO97256.1 - 3e-06 27.4 17.0 0.021 15.1 0.0 6.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_15 PF13429.6 RKO97256.1 - 7.8e-06 25.3 12.0 0.0014 17.9 5.6 4.3 1 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKO97256.1 - 0.00026 20.8 11.4 0.0078 16.2 0.0 5.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKO97256.1 - 0.0019 18.7 6.4 15 6.4 0.0 6.6 7 1 0 7 7 5 0 Tetratricopeptide repeat RPN7 PF10602.9 RKO97256.1 - 0.0047 16.7 1.0 0.14 11.9 1.1 3.4 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 RKO97256.1 - 0.023 14.9 12.7 0.13 12.4 3.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat BTAD PF03704.17 RKO97256.1 - 0.026 15.0 9.5 19 5.7 1.4 5.2 2 1 3 6 6 6 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 RKO97256.1 - 0.053 13.6 0.4 32 4.7 0.0 4.0 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RKO97256.1 - 0.14 12.1 14.5 1.2 9.1 0.2 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat RFX_DNA_binding PF02257.15 RKO97257.1 - 5.2e-25 87.9 0.9 7.1e-25 87.4 0.1 1.7 2 0 0 2 2 2 1 RFX DNA-binding domain HD PF01966.22 RKO97257.1 - 0.11 12.7 0.4 0.25 11.6 0.0 1.7 2 0 0 2 2 2 0 HD domain DUF4707 PF15806.5 RKO97257.1 - 0.46 9.4 4.0 0.76 8.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4707) Methyltransf_16 PF10294.9 RKO97259.1 - 3.1e-08 33.6 0.0 9.7e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 RKO97259.1 - 0.00044 20.1 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO97259.1 - 0.014 15.2 0.0 5.1 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 RKO97259.1 - 0.026 14.1 0.1 0.059 12.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Cation_ATPase_C PF00689.21 RKO97260.1 - 2.1e-47 161.2 2.3 5.5e-47 159.8 2.3 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 RKO97260.1 - 1.2e-35 122.7 0.9 1.2e-35 122.7 0.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RKO97260.1 - 3.7e-23 82.9 0.1 2.2e-22 80.4 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKO97260.1 - 6.8e-16 58.1 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 RKO97260.1 - 2.1e-08 33.8 0.0 4.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKO97260.1 - 4.4e-06 26.6 0.0 0.00031 20.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DoxX_3 PF13781.6 RKO97260.1 - 0.094 13.4 0.6 0.34 11.6 0.6 1.9 1 0 0 1 1 1 0 DoxX-like family PRIMA1 PF16101.5 RKO97260.1 - 0.29 11.2 0.9 16 5.6 0.2 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pox_A14 PF05767.12 RKO97260.1 - 1.8 8.7 4.3 2.4 8.4 0.1 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Ras PF00071.22 RKO97261.1 - 4.3e-56 189.0 0.2 5e-56 188.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO97261.1 - 6.3e-21 74.8 0.0 8.9e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO97261.1 - 7.5e-09 35.3 0.2 8.6e-09 35.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO97261.1 - 2.8e-05 23.8 0.5 7.1e-05 22.4 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 RKO97261.1 - 0.00031 20.8 0.1 0.00049 20.2 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKO97261.1 - 0.00039 20.3 1.0 0.38 10.6 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 RKO97261.1 - 0.031 13.5 0.1 4.3 6.4 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_24 PF13479.6 RKO97261.1 - 0.09 12.5 0.1 0.14 11.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain ABA_GPCR PF12430.8 RKO97262.1 - 4.6e-38 130.8 12.2 4.6e-38 130.8 12.2 2.8 3 1 0 3 3 3 2 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 RKO97262.1 - 5.1e-23 80.9 0.2 2e-22 79.1 0.1 2.1 2 0 0 2 2 2 1 The Golgi pH Regulator (GPHR) Family N-terminal YfzA PF14118.6 RKO97262.1 - 0.3 11.5 7.2 7.4 7.0 0.1 3.6 3 0 0 3 3 3 0 YfzA-like protein PhoLip_ATPase_C PF16212.5 RKO97263.1 - 2.6e-60 204.3 12.4 2.6e-60 204.3 12.4 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RKO97263.1 - 3.2e-16 58.8 0.5 3.2e-16 58.8 0.5 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 RKO97263.1 - 1.9e-10 41.4 0.0 3.1e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKO97263.1 - 1.8e-09 37.6 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 RKO97263.1 - 0.0021 17.9 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Erv26 PF04148.13 RKO97263.1 - 0.005 16.7 0.2 0.012 15.4 0.2 1.6 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 E1-E2_ATPase PF00122.20 RKO97263.1 - 0.034 13.7 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 0 E1-E2 ATPase G-alpha PF00503.20 RKO97265.1 - 5.7e-120 400.7 1.4 6.7e-120 400.5 1.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RKO97265.1 - 7.3e-15 54.8 1.7 4.1e-10 39.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RKO97265.1 - 0.00018 20.9 3.1 0.0079 15.6 0.1 2.7 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region zf-CHC2 PF01807.20 RKO97265.1 - 0.0003 20.5 0.0 0.0011 18.8 0.0 1.9 2 0 0 2 2 2 1 CHC2 zinc finger Roc PF08477.13 RKO97265.1 - 0.0031 17.7 0.2 1.7 8.9 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RKO97265.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 RKO97265.1 - 0.078 13.1 0.0 2.7 8.1 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 RKO97265.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Opi1 PF08618.10 RKO97265.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 PDCD2_C PF04194.13 RKO97266.1 - 7.3e-26 91.3 0.0 7.5e-25 88.0 0.0 2.2 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain CTU2 PF10288.9 RKO97266.1 - 0.062 13.6 0.0 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Rotamase_2 PF13145.6 RKO97266.1 - 0.54 11.1 6.8 0.68 10.8 2.9 2.5 2 0 0 2 2 2 0 PPIC-type PPIASE domain OmpH PF03938.14 RKO97267.1 - 2.4 8.5 28.4 2.8 8.3 19.4 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) GLTT PF01744.20 RKO97268.1 - 0.66 9.8 3.9 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 GLTT repeat (6 copies) Cullin PF00888.22 RKO97269.1 - 5.8e-181 603.3 0.1 5.8e-181 603.3 0.1 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 RKO97269.1 - 3.3e-26 91.1 4.9 3.7e-26 90.9 3.2 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain TelA PF05816.11 RKO97269.1 - 0.037 13.1 2.1 0.047 12.7 0.1 2.2 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Patatin PF01734.22 RKO97269.1 - 0.088 13.0 0.2 0.8 9.8 0.0 2.6 2 2 0 2 2 2 0 Patatin-like phospholipase DUF2780 PF11075.8 RKO97269.1 - 0.31 11.2 2.6 7.7 6.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function VcgC/VcgE (DUF2780) Acyl_transf_1 PF00698.21 RKO97270.1 - 3e-20 73.0 1.6 9.7e-18 64.7 1.4 2.4 1 1 0 2 2 2 1 Acyl transferase domain ubiquitin PF00240.23 RKO97271.1 - 1.4e-06 28.0 0.1 2.6e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 RKO97271.1 - 0.0064 16.9 0.0 0.048 14.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 RKO97271.1 - 0.018 14.9 0.0 0.021 14.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like MCM PF00493.23 RKO97272.1 - 3.2e-100 333.9 0.0 5.8e-100 333.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 RKO97272.1 - 3.2e-31 107.8 4.4 7.5e-31 106.6 4.4 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RKO97272.1 - 4.4e-19 68.7 0.0 1.6e-18 66.9 0.0 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RKO97272.1 - 1.7e-13 51.0 0.1 4.1e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 RKO97272.1 - 6.1e-07 29.0 0.1 2.6e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RKO97272.1 - 5.4e-05 23.2 0.0 0.00017 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO97272.1 - 0.0039 17.6 0.4 0.85 10.0 0.1 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 RKO97272.1 - 0.031 14.1 0.0 0.13 12.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RKO97272.1 - 0.09 12.5 0.1 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 RKO97272.1 - 0.18 12.4 2.7 0.24 12.0 0.2 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal CRISPR_Cse2 PF09485.10 RKO97273.1 - 0.41 11.2 5.4 2 9.0 5.4 2.3 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Hydrophobin PF01185.18 RKO97274.1 - 1.9e-10 41.2 9.7 2.4e-10 40.9 9.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Use1 PF09753.9 RKO97275.1 - 4e-19 69.3 0.0 2.3e-18 66.8 0.0 1.9 2 0 0 2 2 2 1 Membrane fusion protein Use1 Mito_fiss_reg PF05308.11 RKO97275.1 - 0.013 15.6 1.5 0.56 10.2 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Glyco_hydro_26 PF02156.15 RKO97276.1 - 8.9e-09 35.2 0.7 0.00041 19.9 0.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 mRNA_triPase PF02940.15 RKO97277.1 - 2e-31 109.4 0.0 2.6e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Aconitase PF00330.20 RKO97278.1 - 4e-151 504.1 0.0 5e-151 503.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RKO97278.1 - 9.4e-46 155.4 0.0 1.6e-45 154.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Ras PF00071.22 RKO97280.1 - 2.9e-58 196.1 0.0 3.2e-58 195.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO97280.1 - 8.7e-21 74.4 0.0 1.3e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO97280.1 - 1.7e-10 40.6 0.0 2.2e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 RKO97280.1 - 0.00029 20.8 0.0 1.1 9.2 0.0 2.5 2 1 1 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 RKO97280.1 - 0.0006 19.4 0.0 0.0014 18.2 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 RKO97280.1 - 0.0056 16.2 0.0 0.018 14.6 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 RKO97280.1 - 0.0064 16.6 0.0 0.0095 16.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 RKO97280.1 - 0.019 15.0 0.1 0.057 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 RKO97280.1 - 0.066 13.2 0.0 0.16 12.0 0.0 1.7 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain ATP_bind_1 PF03029.17 RKO97280.1 - 0.22 11.3 1.3 2 8.1 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein GCD14 PF08704.10 RKO97281.1 - 6.7e-83 278.1 0.1 7.8e-83 277.9 0.1 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 RKO97281.1 - 2.6e-07 30.6 0.0 3.8e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RKO97281.1 - 4e-06 26.7 0.0 5.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 RKO97281.1 - 9.9e-06 26.5 0.2 1.8e-05 25.7 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 RKO97281.1 - 0.00069 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 RKO97281.1 - 0.0047 17.6 0.0 0.0077 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 RKO97281.1 - 0.0093 15.6 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Fibrillarin PF01269.17 RKO97281.1 - 0.05 12.7 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin RrnaAD PF00398.20 RKO97281.1 - 0.062 12.4 0.0 0.081 12.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 RKO97281.1 - 0.072 13.7 0.0 0.13 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 RKO97281.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase NAD_Gly3P_dh_N PF01210.23 RKO97281.1 - 0.12 12.3 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ribosomal_L1 PF00687.21 RKO97283.1 - 6.9e-19 68.4 0.0 9.8e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MitoNEET_N PF10660.9 RKO97285.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus MLTD_N PF06474.12 RKO97285.1 - 1 9.6 4.7 0.34 11.1 1.3 1.9 2 0 0 2 2 2 0 MltD lipid attachment motif Cyclin PF08613.11 RKO97289.1 - 0.39 11.1 6.2 5 7.5 6.2 2.8 1 1 0 1 1 1 0 Cyclin Spt20 PF12090.8 RKO97289.1 - 1.4 8.5 19.6 0.39 10.3 15.4 2.0 2 0 0 2 2 2 0 Spt20 family Pyridoxal_deC PF00282.19 RKO97290.1 - 1.2e-62 211.9 0.0 1.6e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4641 PF15483.6 RKO97290.1 - 0.033 13.3 0.0 0.045 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) Ras PF00071.22 RKO97292.1 - 1.3e-54 184.2 0.0 1.5e-54 184.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO97292.1 - 1.2e-21 77.1 0.0 1.8e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO97292.1 - 2e-06 27.4 0.0 3e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 RKO97292.1 - 0.018 14.5 0.0 0.023 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 RKO97292.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Dynamin_N PF00350.23 RKO97294.1 - 5.5e-27 94.9 0.0 1.8e-26 93.2 0.0 1.7 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 RKO97294.1 - 3.7e-13 49.3 0.0 5.2e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 RKO97294.1 - 1e-05 25.6 0.0 0.0001 22.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIE-A_C PF11521.8 RKO97294.1 - 0.22 11.8 0.0 0.5 10.7 0.0 1.5 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha NOG1_N PF17835.1 RKO97295.1 - 7.3e-53 178.8 0.5 1.3e-52 178.0 0.5 1.4 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 RKO97295.1 - 2.1e-27 94.8 1.0 4e-27 93.9 1.0 1.5 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 RKO97295.1 - 1.3e-25 88.9 0.0 3.1e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 RKO97295.1 - 1.6e-18 66.9 0.0 3e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKO97295.1 - 7.3e-10 38.6 0.0 1.4e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 RKO97295.1 - 0.00039 20.5 0.0 0.41 10.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 RKO97295.1 - 0.058 13.8 0.1 0.36 11.2 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain SRPRB PF09439.10 RKO97295.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 RKO97295.1 - 0.11 12.4 0.0 1.1 9.2 0.0 2.5 2 1 0 2 2 2 0 RsgA GTPase DUF4870 PF09685.10 RKO97297.1 - 0.027 14.6 3.6 0.041 14.0 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) VKOR PF07884.14 RKO97297.1 - 0.47 10.6 12.3 1.2 9.4 12.3 1.5 1 1 0 1 1 1 0 Vitamin K epoxide reductase family SHQ1 PF04925.15 RKO97298.1 - 2.3e-50 170.6 0.7 3e-50 170.2 0.7 1.1 1 0 0 1 1 1 1 SHQ1 protein GTP1_OBG PF01018.22 RKO97299.1 - 1.3e-32 112.5 0.4 1.8e-32 112.1 0.4 1.2 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 RKO97299.1 - 1.5e-21 76.6 0.0 2.3e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKO97299.1 - 7.6e-11 41.8 0.0 1.2e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 RKO97299.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.4 1 1 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 RKO97299.1 - 0.0087 15.6 0.0 0.37 10.3 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 RKO97299.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family MeaB PF03308.16 RKO97299.1 - 0.098 11.6 0.1 0.53 9.2 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 RKO97299.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 RKO97299.1 - 0.13 12.3 0.0 11 6.0 0.0 2.3 1 1 1 2 2 2 0 Dynamin family P5CR_dimer PF14748.6 RKO97301.1 - 9.9e-34 115.7 2.1 9.9e-34 115.7 2.1 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 RKO97301.1 - 1.2e-17 64.3 2.6 1.2e-17 64.3 2.6 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 RKO97301.1 - 0.0055 16.8 0.1 0.021 14.9 0.1 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.23 RKO97301.1 - 0.08 12.9 5.3 0.22 11.5 3.1 2.5 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4407 PF14362.6 RKO97302.1 - 0.014 14.8 0.4 0.018 14.4 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 RKO97302.1 - 0.07 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Septum formation initiator DUF3138 PF11336.8 RKO97302.1 - 2.1 6.9 7.8 3.1 6.3 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CS PF04969.16 RKO97303.1 - 4.4e-08 34.0 0.0 6.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 CS domain Spore_coat_CotO PF14153.6 RKO97303.1 - 0.074 13.0 2.9 0.083 12.8 2.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Rtt106 PF08512.12 RKO97304.1 - 7.5e-15 55.1 0.0 2.3e-14 53.6 0.0 1.7 1 1 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 RKO97304.1 - 0.079 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain DUF1179 PF06678.11 RKO97304.1 - 1.4 8.9 4.8 0.59 10.2 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) SDA1 PF05285.12 RKO97304.1 - 2.9 7.2 21.3 0.22 10.9 16.1 1.6 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 RKO97304.1 - 3 5.9 17.7 5.4 5.1 17.7 1.3 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 RKO97304.1 - 9.3 6.3 26.7 0.37 10.9 20.3 1.8 2 0 0 2 2 2 0 YL1 nuclear protein MOZ_SAS PF01853.18 RKO97306.1 - 1.1e-70 237.0 0.0 1.5e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 RKO97306.1 - 8.6e-20 70.1 1.5 8.6e-20 70.1 1.5 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 RKO97306.1 - 0.0031 17.9 0.0 0.0051 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKO97306.1 - 0.068 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family STIMATE PF12400.8 RKO97307.1 - 1e-36 126.2 4.0 1.3e-36 125.9 3.0 1.6 2 0 0 2 2 2 1 STIMATE family Stk19 PF10494.9 RKO97308.1 - 1.3e-05 25.0 0.0 1.7e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 AIRC PF00731.20 RKO97309.1 - 1.5e-58 196.6 2.9 1.5e-58 196.6 2.9 2.7 3 0 0 3 3 3 1 AIR carboxylase ATP-grasp PF02222.22 RKO97309.1 - 2.5e-53 180.1 0.0 4e-53 179.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 RKO97309.1 - 3e-16 58.8 0.0 6.4e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 RKO97309.1 - 2.5e-11 43.5 0.1 4.6e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 RKO97309.1 - 0.00057 19.5 0.0 0.0017 17.9 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PrpR_N PF06506.11 RKO97309.1 - 0.045 13.3 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 Propionate catabolism activator CoA_binding_2 PF13380.6 RKO97309.1 - 0.084 13.4 1.1 8.5 6.9 0.0 3.7 2 2 1 4 4 4 0 CoA binding domain ThiF PF00899.21 RKO97311.1 - 3.2e-103 344.3 0.0 4.1e-70 235.9 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 RKO97311.1 - 1.1e-91 307.2 0.0 1.8e-91 306.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 RKO97311.1 - 2.7e-31 108.1 0.0 5.3e-31 107.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 RKO97311.1 - 1.3e-27 95.8 0.4 2.6e-27 94.8 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 RKO97311.1 - 7.9e-26 90.0 0.9 3.2e-25 88.1 0.9 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Lant_dehydr_N PF04738.13 RKO97311.1 - 0.083 11.0 0.0 0.13 10.3 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus SGL PF08450.12 RKO97313.1 - 0.022 14.4 0.0 0.065 12.8 0.0 1.8 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region AA_permease_2 PF13520.6 RKO97314.1 - 1.1e-32 113.4 42.8 1.1e-32 113.4 42.8 1.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RKO97314.1 - 4.1e-18 65.2 42.6 7.1e-18 64.4 42.6 1.4 1 1 0 1 1 1 1 Amino acid permease ATE_C PF04377.15 RKO97315.1 - 4.4e-47 160.1 0.8 6.1e-47 159.6 0.8 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 RKO97315.1 - 2.9e-24 85.3 3.6 5.8e-24 84.3 2.3 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus TPR_2 PF07719.17 RKO97316.1 - 2.5e-11 42.8 0.4 0.0005 20.0 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKO97316.1 - 4.1e-11 42.2 0.0 3.3e-05 23.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 RKO97316.1 - 2.3e-08 34.5 0.2 2.3e-08 34.5 0.2 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO97316.1 - 2.2e-07 30.9 9.2 0.00045 20.3 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat RPAP3_C PF13877.6 RKO97316.1 - 2.1e-05 25.0 0.0 4.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_11 PF13414.6 RKO97316.1 - 9.4e-05 22.0 0.3 0.0039 16.8 0.0 3.0 3 1 1 4 4 4 1 TPR repeat TPR_19 PF14559.6 RKO97316.1 - 0.00021 21.7 3.5 0.006 17.1 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 RKO97316.1 - 0.00076 19.5 0.0 0.038 14.2 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKO97316.1 - 0.0015 18.4 1.6 0.019 14.9 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 RKO97316.1 - 0.003 18.1 1.3 11 6.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO97316.1 - 0.02 15.1 0.5 0.044 14.0 0.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RKO97316.1 - 0.036 14.9 7.2 1.9 9.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 RKO97316.1 - 0.051 14.0 3.0 1.1 9.8 0.1 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 RKO97316.1 - 0.19 12.0 1.6 2.3 8.6 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat PhoH PF02562.16 RKO97318.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.15 RKO97318.1 - 0.013 15.6 0.0 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 RKO97318.1 - 0.08 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase Mito_carr PF00153.27 RKO97320.1 - 3.9e-24 84.4 0.6 7.9e-15 54.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Dor1 PF04124.12 RKO97321.1 - 6e-32 110.6 0.1 2.1e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 RKO97321.1 - 1.9e-06 27.9 0.0 4.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 RKO97321.1 - 0.00011 22.3 0.0 0.00025 21.1 0.0 1.5 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 dsDNA_bind PF01984.20 RKO97322.1 - 2.7e-35 121.0 0.0 3.6e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4201 PF13870.6 RKO97323.1 - 3.9e-32 111.4 13.7 3.9e-32 111.4 13.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) KxDL PF10241.9 RKO97323.1 - 0.0049 17.1 5.1 0.0087 16.3 3.7 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein Neur_chan_memb PF02932.16 RKO97323.1 - 1.1 9.2 3.3 1.2 9.1 2.6 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_C10 PF01640.17 RKO97323.1 - 2.5 8.4 4.7 4.5 7.6 1.2 2.1 1 1 1 2 2 2 0 Peptidase C10 family Arm PF00514.23 RKO97324.1 - 9.5e-30 101.7 0.0 8e-14 51.1 0.0 2.4 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat IBB PF01749.20 RKO97324.1 - 9e-25 86.9 0.8 2.3e-23 82.4 1.0 2.1 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 RKO97324.1 - 2.9e-11 43.6 0.0 2e-08 34.5 0.0 2.4 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 RKO97324.1 - 9.1e-11 41.1 0.0 4.1e-06 26.6 0.0 3.1 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.6 RKO97324.1 - 6.3e-09 36.1 0.1 2.8e-07 30.9 0.1 2.7 2 1 1 3 3 3 2 HEAT-like repeat HEAT_PBS PF03130.16 RKO97324.1 - 0.0084 16.7 0.0 0.7 10.7 0.0 2.5 2 0 0 2 2 2 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 RKO97324.1 - 0.011 16.0 0.1 0.033 14.4 0.1 1.8 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 FmrO PF07091.11 RKO97324.1 - 0.031 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) G6PD_C PF02781.16 RKO97325.1 - 5.7e-117 390.0 0.0 7.6e-117 389.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 RKO97325.1 - 1.2e-60 205.1 0.3 1.8e-60 204.6 0.3 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain NuiA PF07924.11 RKO97325.1 - 0.13 12.7 0.1 1.5 9.2 0.1 2.2 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein Lipase_GDSL_2 PF13472.6 RKO97326.1 - 6.9e-12 46.1 0.2 3.6e-11 43.8 0.0 2.3 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RKO97326.1 - 0.00073 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sensor_TM1 PF13755.6 RKO97327.1 - 0.92 9.3 3.3 6.3 6.6 0.2 3.2 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain vWA-TerF-like PF10138.9 RKO97327.1 - 0.99 9.5 22.1 0.98 9.5 1.0 6.1 2 2 5 8 8 8 0 vWA found in TerF C terminus CLCA PF08434.11 RKO97327.1 - 1.5 8.1 10.5 8.8 5.6 0.1 4.4 4 0 0 4 4 4 0 Calcium-activated chloride channel N terminal His_Phos_2 PF00328.22 RKO97328.1 - 5.2e-72 243.3 0.0 6.9e-72 242.9 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 RKO97328.1 - 1.6e-35 121.1 0.0 3e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 RKO97328.1 - 4.2e-07 29.8 0.0 7.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 RKO97328.1 - 0.013 15.5 0.1 0.037 14.1 0.1 1.8 1 1 0 1 1 1 0 ATP-grasp domain EZH2_N PF18601.1 RKO97328.1 - 0.18 12.1 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 EZH2 N-terminal domain Acetyltransf_3 PF13302.7 RKO97330.1 - 8.2e-23 81.6 0.0 1.3e-22 80.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 RKO97330.1 - 3.2e-06 27.4 0.0 4.8e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 RKO97330.1 - 9.8e-06 25.8 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 RKO97330.1 - 6.3e-05 22.7 0.6 0.036 13.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKO97330.1 - 0.00064 19.6 0.0 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 RKO97330.1 - 0.01 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 RKO97330.1 - 0.017 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ferric_reduct PF01794.19 RKO97334.1 - 4.2e-10 39.8 11.8 4.2e-10 39.8 11.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component DnaJ PF00226.31 RKO97336.1 - 3.5e-13 49.5 0.2 6.1e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Peptidase_C97 PF05903.14 RKO97338.1 - 6.4e-29 100.7 0.0 7e-29 100.6 0.0 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 RKO97338.1 - 0.0052 17.1 0.0 0.0062 16.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin retinol acyltransferase A_deaminase PF00962.22 RKO97339.1 - 7.9e-125 416.5 0.0 1e-124 416.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase AAA PF00004.29 RKO97340.1 - 6.5e-43 146.3 0.0 1.4e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO97340.1 - 2.3e-12 46.5 0.1 4.6e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 RKO97340.1 - 5.3e-10 39.1 0.1 1.2e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 RKO97340.1 - 3.7e-07 30.4 0.0 1.1e-06 28.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RKO97340.1 - 1.3e-06 28.5 0.1 2.8e-05 24.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO97340.1 - 1.8e-06 28.4 0.0 0.00053 20.4 0.1 2.8 2 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 RKO97340.1 - 9.8e-06 25.4 0.0 2.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 RKO97340.1 - 0.00019 21.7 0.1 0.0045 17.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RKO97340.1 - 0.001 18.3 0.0 0.0025 17.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 RKO97340.1 - 0.0011 18.6 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 RKO97340.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKO97340.1 - 0.002 18.7 0.0 0.006 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 RKO97340.1 - 0.0032 16.9 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 RKO97340.1 - 0.0042 17.1 0.0 0.0084 16.1 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 RKO97340.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 RKO97340.1 - 0.007 15.6 0.2 0.016 14.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_3 PF07726.11 RKO97340.1 - 0.0084 16.0 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 RKO97340.1 - 0.0091 16.4 0.0 0.023 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 RKO97340.1 - 0.011 15.8 0.0 0.031 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain Thymidylate_kin PF02223.17 RKO97340.1 - 0.011 15.4 0.1 2.4 7.8 0.0 2.7 2 1 0 2 2 2 0 Thymidylate kinase ATPase PF06745.13 RKO97340.1 - 0.012 15.0 0.4 0.044 13.1 0.0 2.0 3 0 0 3 3 3 0 KaiC IstB_IS21 PF01695.17 RKO97340.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 RKO97340.1 - 0.019 14.7 0.0 0.063 13.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain DUF4600 PF15372.6 RKO97340.1 - 0.038 14.4 1.4 0.092 13.2 1.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) NACHT PF05729.12 RKO97340.1 - 0.044 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 RKO97340.1 - 0.076 12.6 0.5 0.4 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RKO97340.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Med4 PF10018.9 RKO97340.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 PhoH PF02562.16 RKO97340.1 - 0.09 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 RKO97340.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKO97340.1 - 0.092 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Prot_ATP_OB_N PF17758.1 RKO97340.1 - 0.15 11.7 0.2 0.37 10.5 0.0 1.7 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain AAA_11 PF13086.6 RKO97340.1 - 0.22 11.3 0.2 0.48 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain GreA_GreB_N PF03449.15 RKO97340.1 - 2.5 8.3 5.9 19 5.5 0.0 3.2 4 0 0 4 4 2 0 Transcription elongation factor, N-terminal RhoGAP PF00620.27 RKO97341.1 - 2.1e-05 24.4 0.0 5.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 RKO97341.1 - 0.0037 17.3 0.0 0.01 15.8 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 RKO97341.1 - 0.0058 16.9 0.0 0.015 15.6 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Myotub-related PF06602.14 RKO97342.1 - 3.3e-108 361.8 0.0 3.7e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 RKO97342.1 - 0.0017 18.2 0.1 0.003 17.4 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKO97342.1 - 0.0032 17.1 0.1 0.0048 16.5 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 RKO97342.1 - 0.028 14.4 0.2 0.054 13.5 0.2 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family NTP_transferase PF00483.23 RKO97343.1 - 2.1e-13 50.5 0.0 1.2e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 RKO97343.1 - 5.1e-09 36.7 0.3 8.1e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 RKO97343.1 - 2.6e-08 33.3 7.2 7.7e-05 22.3 5.6 3.3 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 RKO97343.1 - 0.00025 19.3 0.6 0.00097 17.4 0.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Img2 PF05046.14 RKO97344.1 - 1.6e-12 47.5 0.0 2.1e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) B9-C2 PF07162.11 RKO97346.1 - 3.9e-29 102.0 0.0 4.8e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein BK_channel_a PF03493.18 RKO97349.1 - 2.9e-24 85.1 0.0 3.1e-22 78.6 0.0 2.4 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 RKO97349.1 - 2.9e-11 43.2 2.0 2.9e-11 43.2 2.0 2.2 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 RKO97349.1 - 7.1e-06 25.4 14.5 7.1e-06 25.4 14.5 1.7 2 0 0 2 2 2 1 Ion transport protein Prok-E2_B PF14461.6 RKO97349.1 - 0.14 11.8 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Lig_chan PF00060.26 RKO97349.1 - 0.4 10.5 4.1 0.094 12.6 0.5 1.7 2 0 0 2 2 2 0 Ligand-gated ion channel DUF2975 PF11188.8 RKO97349.1 - 5.4 6.9 10.8 0.17 11.7 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Rubredoxin_2 PF18073.1 RKO97350.1 - 1.5 8.6 4.7 11 5.8 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin metal binding domain PhoLip_ATPase_C PF16212.5 RKO97351.1 - 7.5e-69 232.2 22.9 7.5e-69 232.2 22.9 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 RKO97351.1 - 1.1e-20 73.1 1.6 1.1e-20 73.1 1.6 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 RKO97351.1 - 1.7e-14 53.7 0.0 4.8e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RKO97351.1 - 4.6e-11 43.4 1.7 2.4e-06 28.0 0.7 3.0 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 RKO97351.1 - 9e-06 25.3 0.0 7.9e-05 22.3 0.0 2.6 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 RKO97351.1 - 0.00044 20.1 0.5 0.009 15.8 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNA_pol_Rpb5_C PF01191.19 RKO97352.1 - 9.6e-33 111.9 0.1 2.3e-32 110.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 RKO97352.1 - 1.2e-26 93.1 0.7 1.9e-26 92.4 0.7 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Rubrerythrin PF02915.17 RKO97352.1 - 0.005 17.2 0.1 0.0078 16.6 0.1 1.4 1 0 0 1 1 1 1 Rubrerythrin PDT PF00800.18 RKO97352.1 - 0.052 13.4 0.1 0.078 12.8 0.1 1.3 1 0 0 1 1 1 0 Prephenate dehydratase DDE_Tnp_1 PF01609.21 RKO97352.1 - 0.099 12.3 0.1 0.17 11.5 0.1 1.5 1 1 0 1 1 1 0 Transposase DDE domain Prefoldin_2 PF01920.20 RKO97353.1 - 1.2e-18 67.0 7.4 1.5e-18 66.7 7.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.11 RKO97353.1 - 0.0032 17.5 0.9 0.0032 17.5 0.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Occludin_ELL PF07303.13 RKO97353.1 - 0.0093 16.7 2.5 3.4 8.4 1.3 2.1 2 0 0 2 2 2 2 Occludin homology domain Syntaxin_2 PF14523.6 RKO97353.1 - 0.016 15.6 7.0 0.26 11.7 2.0 2.3 2 1 0 2 2 2 0 Syntaxin-like protein YscO PF07321.12 RKO97353.1 - 0.021 14.8 3.3 0.046 13.7 0.2 1.9 1 1 1 2 2 2 0 Type III secretion protein YscO TPR_MLP1_2 PF07926.12 RKO97353.1 - 0.028 14.5 7.6 0.33 11.0 1.0 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Alpha-2-MRAP_C PF06401.11 RKO97353.1 - 0.03 14.3 2.7 0.036 14.0 2.7 1.0 1 0 0 1 1 1 0 Alpha-2-macroglobulin RAP, C-terminal domain YabA PF06156.13 RKO97353.1 - 0.033 14.8 2.6 2.6 8.7 0.6 2.1 2 0 0 2 2 2 0 Initiation control protein YabA DUF4298 PF14131.6 RKO97353.1 - 0.05 13.6 3.2 1.6 8.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) GLTSCR1 PF15249.6 RKO97353.1 - 0.053 14.0 1.4 0.07 13.6 0.4 1.7 2 0 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein Syntaxin-6_N PF09177.11 RKO97353.1 - 0.071 13.7 3.2 0.43 11.2 3.2 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ZapB PF06005.12 RKO97353.1 - 0.12 12.8 10.5 2 8.9 10.5 2.1 1 1 0 1 1 1 0 Cell division protein ZapB FliD_C PF07195.12 RKO97353.1 - 0.27 10.6 4.9 0.54 9.6 4.9 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF5446 PF17522.2 RKO97353.1 - 0.47 10.7 3.2 0.48 10.6 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5446) DivIVA PF05103.13 RKO97353.1 - 0.52 10.4 7.4 1.5 9.0 7.4 1.7 1 1 0 1 1 1 0 DivIVA protein Snapin_Pallidin PF14712.6 RKO97353.1 - 0.61 10.6 6.3 17 5.9 0.1 2.7 1 1 1 2 2 2 0 Snapin/Pallidin DUF148 PF02520.17 RKO97353.1 - 0.67 10.1 8.6 0.83 9.8 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 KASH_CCD PF14662.6 RKO97353.1 - 0.74 9.6 9.9 6.6 6.5 0.2 2.1 1 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 RKO97353.1 - 0.99 9.4 8.7 1.6 8.7 1.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FliJ PF02050.16 RKO97353.1 - 1.1 9.5 10.0 0.52 10.5 1.0 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein TMF_DNA_bd PF12329.8 RKO97353.1 - 4.8 7.3 10.0 2.5 8.1 0.9 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 RKO97353.1 - 5.4 7.3 8.5 9.8 6.5 1.5 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Tub PF01167.18 RKO97354.1 - 1.3e-33 116.8 0.1 1.4e-33 116.7 0.1 1.0 1 0 0 1 1 1 1 Tub family AAA PF00004.29 RKO97355.1 - 1e-28 100.4 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKO97355.1 - 2.6e-08 34.5 0.3 1.2e-07 32.3 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKO97355.1 - 4.8e-07 30.1 0.0 1.2e-06 28.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 RKO97355.1 - 6.5e-06 26.2 0.0 4.3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 RKO97355.1 - 8.9e-06 25.4 1.9 0.022 14.4 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_18 PF13238.6 RKO97355.1 - 1.1e-05 26.0 0.0 1.4e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 RKO97355.1 - 6.4e-05 22.9 0.0 0.00021 21.3 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 RKO97355.1 - 0.00011 21.9 0.1 0.00018 21.3 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKO97355.1 - 0.0006 20.0 0.1 0.0011 19.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 RKO97355.1 - 0.00068 19.6 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 RKO97355.1 - 0.00076 19.3 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_11 PF13086.6 RKO97355.1 - 0.00087 19.2 0.1 0.0021 17.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 RKO97355.1 - 0.0018 18.5 0.1 0.0053 17.0 0.1 1.6 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 RKO97355.1 - 0.0024 18.3 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 RKO97355.1 - 0.0028 17.2 0.0 0.0042 16.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_2 PF07724.14 RKO97355.1 - 0.0038 17.3 0.0 0.008 16.3 0.0 1.5 1 1 1 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RKO97355.1 - 0.0043 16.8 0.0 0.0092 15.7 0.0 1.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 RKO97355.1 - 0.0046 16.7 0.1 0.011 15.4 0.0 1.8 2 0 0 2 2 2 1 Cytidylate kinase Mg_chelatase PF01078.21 RKO97355.1 - 0.0068 15.8 0.4 0.031 13.6 0.0 2.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RKO97355.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 RKO97355.1 - 0.012 15.7 0.0 0.017 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 RKO97355.1 - 0.018 14.8 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 RKO97355.1 - 0.024 14.4 0.0 0.057 13.1 0.0 1.7 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 RKO97355.1 - 0.036 13.8 0.0 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 RKO97355.1 - 0.037 14.4 0.3 0.12 12.7 0.1 1.8 1 1 1 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 RKO97355.1 - 0.042 13.6 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 RKO97355.1 - 0.054 14.0 0.0 0.082 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter KAP_NTPase PF07693.14 RKO97355.1 - 0.06 12.6 0.0 2.4 7.3 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain TIP49 PF06068.13 RKO97355.1 - 0.065 12.4 0.0 0.086 12.0 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 RKO97355.1 - 0.065 13.1 0.0 11 5.8 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 RKO97355.1 - 0.072 12.4 0.1 2.1 7.6 0.0 2.5 2 1 0 2 2 2 0 FtsK/SpoIIIE family Parvo_NS1 PF01057.17 RKO97355.1 - 0.079 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.23 RKO97355.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.7 2 0 0 2 2 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 RKO97355.1 - 0.14 12.0 0.0 0.6 10.0 0.0 1.8 2 0 0 2 2 2 0 NTPase PhoH PF02562.16 RKO97355.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SRP54 PF00448.22 RKO97355.1 - 0.17 11.5 0.0 0.45 10.1 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DnaB_C PF03796.15 RKO97355.1 - 0.21 10.9 0.0 1 8.6 0.0 1.7 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain RsgA_GTPase PF03193.16 RKO97355.1 - 0.24 11.3 0.0 0.4 10.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 RKO97355.1 - 0.32 10.2 0.0 0.42 9.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_13 PF13166.6 RKO97355.1 - 0.38 9.3 0.0 0.47 9.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Ribosomal_L29e PF01779.17 RKO97356.1 - 3.2e-19 68.9 9.2 3.9e-19 68.7 9.2 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family JAB PF01398.21 RKO97357.1 - 1.8e-33 115.0 0.0 3.1e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 RKO97357.1 - 4.6e-12 46.3 0.5 7.9e-12 45.6 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 RKO97357.1 - 4e-07 29.8 0.0 7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 RKO97357.1 - 0.039 14.0 0.1 0.09 12.8 0.0 1.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) LPMO_10 PF03067.15 RKO97360.1 - 4.2e-10 40.6 0.6 3.2e-09 37.7 0.0 2.5 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Metallothi_Euk2 PF12809.7 RKO97360.1 - 1.6 9.0 6.1 2.8 8.3 4.2 2.1 2 0 0 2 2 2 0 Eukaryotic metallothionein TRAM_LAG1_CLN8 PF03798.16 RKO97361.1 - 1.1e-32 113.3 17.8 1.5e-32 113.0 17.8 1.1 1 0 0 1 1 1 1 TLC domain RIO1 PF01163.22 RKO97362.1 - 5.7e-66 221.7 0.0 5.7e-66 221.7 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 RKO97362.1 - 0.00017 21.6 0.1 0.0045 16.9 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family CDC45 PF02724.14 RKO97362.1 - 0.0048 15.3 2.1 0.0054 15.1 2.1 1.2 1 0 0 1 1 1 1 CDC45-like protein Kdo PF06293.14 RKO97362.1 - 0.0086 15.4 0.3 2.6 7.4 0.1 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SEEEED PF14797.6 RKO97362.1 - 0.19 11.9 12.9 0.29 11.3 12.9 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex Cys_Met_Meta_PP PF01053.20 RKO97363.1 - 6.4e-130 433.1 0.0 7.8e-130 432.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 RKO97363.1 - 0.00017 20.9 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class I and II DUF2340 PF10209.9 RKO97364.1 - 4.1e-39 133.8 0.0 4.7e-39 133.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) GYR PF02756.14 RKO97364.1 - 0.016 14.9 0.5 0.03 14.0 0.5 1.4 1 0 0 1 1 1 0 GYR motif DUF2847 PF11009.8 RKO97364.1 - 0.19 11.7 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Adaptin_N PF01602.20 RKO97365.1 - 3.5e-113 378.9 0.0 4.1e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RKO97365.1 - 5.6e-08 33.0 0.0 8.1e-07 29.2 0.0 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 CRISPR_Cse2 PF09485.10 RKO97365.1 - 0.0052 17.3 0.1 0.016 15.8 0.1 1.8 1 0 0 1 1 1 1 CRISPR-associated protein Cse2 (CRISPR_cse2) HEAT PF02985.22 RKO97365.1 - 0.0079 16.4 0.4 12 6.5 0.0 4.9 4 1 1 5 5 5 1 HEAT repeat Apolipoprotein PF01442.18 RKO97366.1 - 3.1e-06 27.2 33.7 0.00044 20.2 14.4 2.8 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Borrelia_P83 PF05262.11 RKO97366.1 - 0.061 11.8 23.4 0.074 11.5 22.9 1.4 1 1 0 1 1 1 0 Borrelia P83/100 protein Phasin_2 PF09361.10 RKO97366.1 - 0.67 10.3 45.7 2.6 8.4 18.5 3.1 1 1 0 2 2 2 0 Phasin protein TipAS PF07739.13 RKO97366.1 - 1.5 9.4 19.4 0.38 11.3 11.1 2.7 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain Muted PF14942.6 RKO97366.1 - 2.5 8.4 7.9 5.3 7.4 4.7 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein DUF883 PF05957.13 RKO97366.1 - 3 8.5 47.0 2.2 8.9 12.8 4.8 1 1 4 5 5 5 0 Bacterial protein of unknown function (DUF883) SHD1 PF03983.12 RKO97367.1 - 6.6e-25 86.7 0.0 6.8e-25 86.7 0.0 1.0 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 Mito_carr PF00153.27 RKO97368.1 - 4.6e-61 202.8 8.4 3.3e-22 78.2 0.3 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 RKO97368.1 - 0.054 12.6 0.1 8.6 5.4 0.0 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease DUF4235 PF14019.6 RKO97368.1 - 0.17 12.0 0.3 0.17 12.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) WD40 PF00400.32 RKO97370.1 - 2.3e-09 37.7 0.8 0.027 15.3 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97370.1 - 0.029 14.7 0.0 5.8 7.3 0.0 3.7 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 RKO97372.1 - 0.0021 18.1 4.4 0.0054 16.8 4.4 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Nitroreductase PF00881.24 RKO97372.1 - 2.2 8.3 7.2 6.9 6.7 0.3 2.7 2 1 0 3 3 3 0 Nitroreductase family LRR_4 PF12799.7 RKO97374.1 - 6.9e-16 58.1 20.1 3.7e-08 33.5 0.9 3.9 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 RKO97374.1 - 8.9e-15 54.6 6.1 2.3e-14 53.3 3.6 2.2 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 RKO97374.1 - 3.3e-12 46.0 18.9 8.6e-07 28.6 0.5 3.2 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 RKO97374.1 - 0.012 15.6 4.7 2.9 8.2 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat DUF1043 PF06295.12 RKO97374.1 - 0.03 14.3 5.9 0.12 12.4 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1043) LRR_1 PF00560.33 RKO97374.1 - 0.032 14.8 12.4 11 7.0 0.9 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat HR1 PF02185.16 RKO97375.1 - 5.5e-15 55.2 3.8 5.1e-09 36.1 0.4 2.3 2 0 0 2 2 2 2 Hr1 repeat C2 PF00168.30 RKO97375.1 - 0.00019 21.7 0.0 0.0003 21.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain Uds1 PF15456.6 RKO97375.1 - 0.15 12.2 4.1 0.11 12.7 1.0 2.1 2 0 0 2 2 2 0 Up-regulated During Septation DUF5344 PF17279.2 RKO97376.1 - 0.083 13.5 0.1 0.83 10.3 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5344) FHIPEP PF00771.20 RKO97376.1 - 0.12 10.8 0.0 0.24 9.8 0.0 1.4 1 0 0 1 1 1 0 FHIPEP family Ribosomal_L36 PF00444.18 RKO97377.1 - 9.3e-12 45.0 6.9 1.1e-11 44.7 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 WD40 PF00400.32 RKO97378.1 - 3.4e-12 46.7 18.9 0.0027 18.5 0.0 8.2 8 1 0 8 8 8 4 WD domain, G-beta repeat zf-C2H2_jaz PF12171.8 RKO97379.1 - 0.00011 22.4 0.1 0.00018 21.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding TRAPP PF04051.16 RKO97380.1 - 6.2e-32 110.3 0.0 7.3e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CAAD PF14159.6 RKO97380.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Peptidase_M41 PF01434.18 RKO97381.1 - 9.9e-62 208.2 0.2 2.1e-61 207.1 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 RKO97381.1 - 1.8e-44 151.4 0.0 5e-44 149.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO97381.1 - 8.7e-10 38.3 0.0 2.8e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 RKO97381.1 - 2.7e-06 27.9 2.1 0.0021 18.5 0.1 3.8 4 1 0 5 5 4 1 AAA ATPase domain TIP49 PF06068.13 RKO97381.1 - 2.6e-05 23.6 0.0 4.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 RKO97381.1 - 5.2e-05 23.1 0.0 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 RKO97381.1 - 0.0003 20.6 0.1 0.0011 18.7 0.0 2.0 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 RKO97381.1 - 0.0003 20.8 0.0 0.0019 18.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKO97381.1 - 0.0011 19.2 0.1 0.011 16.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 RKO97381.1 - 0.0014 17.8 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 RKO97381.1 - 0.0023 18.5 0.0 0.0081 16.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain Peptidase_M50B PF13398.6 RKO97381.1 - 0.0025 17.5 0.6 0.089 12.4 0.0 2.2 2 0 0 2 2 2 1 Peptidase M50B-like AAA_33 PF13671.6 RKO97381.1 - 0.0038 17.4 0.1 0.03 14.5 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 RKO97381.1 - 0.0068 16.1 0.1 0.018 14.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 RKO97381.1 - 0.034 14.1 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 RKO97381.1 - 0.043 13.1 0.6 0.33 10.2 0.2 2.2 1 1 1 2 2 2 0 Zeta toxin AAA_25 PF13481.6 RKO97381.1 - 0.046 13.3 0.2 0.29 10.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RKO97381.1 - 0.048 13.1 0.2 0.12 11.7 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 RKO97381.1 - 0.048 13.8 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 RKO97381.1 - 0.048 14.1 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RKO97381.1 - 0.062 13.5 2.0 0.073 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 RKO97381.1 - 0.13 12.1 0.0 0.39 10.5 0.0 1.8 2 1 0 2 2 2 0 Bacterial dnaA protein ATPase_2 PF01637.18 RKO97381.1 - 0.13 12.1 0.0 6.9 6.5 0.0 2.3 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 RKO97381.1 - 0.14 11.6 0.0 1 8.9 0.0 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RKO97381.1 - 0.19 12.1 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 RKO97381.1 - 0.19 11.6 1.6 1.1 9.2 0.1 2.6 3 0 0 3 3 3 0 NACHT domain WD40 PF00400.32 RKO97382.1 - 2.2e-43 145.4 14.9 3.4e-08 34.0 0.1 7.2 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97382.1 - 9.4e-11 41.9 0.1 0.0022 18.3 0.0 3.9 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO97382.1 - 2.1e-06 26.7 3.6 0.098 11.3 0.1 4.3 4 2 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 RKO97382.1 - 0.00047 19.2 3.3 0.25 10.3 0.1 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 RKO97382.1 - 0.0043 17.0 0.0 0.0094 15.9 0.0 1.6 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.16 RKO97382.1 - 0.053 12.0 0.2 0.22 10.0 0.1 2.0 2 1 1 3 3 3 0 Cytochrome D1 heme domain LisH_TPL PF17814.1 RKO97382.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 LisH-like dimerisation domain PALB2_WD40 PF16756.5 RKO97382.1 - 0.35 9.7 2.3 5.4 5.8 0.1 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Kin17_mid PF10357.9 RKO97383.1 - 2.5e-37 127.6 0.0 3e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 RKO97383.1 - 0.00051 20.2 0.4 0.00086 19.5 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 RKO97383.1 - 0.0087 16.4 1.3 0.017 15.5 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 RKO97383.1 - 0.13 12.6 0.1 0.48 10.8 0.0 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) PIGA PF08288.12 RKO97384.1 - 2.7e-42 143.2 2.0 3.3e-42 143.0 0.9 1.7 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 RKO97384.1 - 2.6e-31 108.9 1.6 6.2e-31 107.7 1.6 1.7 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 RKO97384.1 - 7.1e-26 90.8 0.0 1.1e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RKO97384.1 - 1.2e-20 74.3 0.1 2.4e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RKO97384.1 - 7.4e-14 52.5 0.3 1.5e-13 51.5 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 RKO97384.1 - 1.6e-05 25.2 0.3 0.00071 19.9 0.0 3.0 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 RKO97384.1 - 5.5e-05 23.2 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_5 PF08323.11 RKO97384.1 - 0.004 16.9 0.5 0.012 15.3 0.4 1.8 1 1 1 2 2 2 1 Starch synthase catalytic domain UPF0220 PF05255.11 RKO97384.1 - 0.1 12.1 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) CPSase_L_D2 PF02786.17 RKO97390.1 - 3.4e-93 311.0 0.0 1.1e-80 270.2 0.0 2.7 2 1 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 RKO97390.1 - 6e-37 126.7 0.2 1.5e-36 125.4 0.2 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 RKO97390.1 - 4.8e-12 45.8 0.0 3.5e-07 29.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 RKO97390.1 - 1.5e-11 44.3 0.0 1.1e-06 28.4 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 RKO97390.1 - 2.2e-07 30.7 0.1 0.016 14.9 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 RKO97390.1 - 0.00017 21.2 0.0 0.041 13.5 0.0 2.8 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 RKO97390.1 - 0.00067 19.2 0.0 0.26 10.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain HTH_23 PF13384.6 RKO97390.1 - 0.0086 15.9 0.4 0.37 10.7 0.0 2.8 2 0 0 2 2 2 1 Homeodomain-like domain Semialdhyde_dh PF01118.24 RKO97390.1 - 0.081 13.4 0.0 0.38 11.2 0.0 2.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Med31 PF05669.12 RKO97391.1 - 1.3e-35 121.3 9.5 1.4e-35 121.1 9.5 1.0 1 0 0 1 1 1 1 SOH1 BRO1 PF03097.18 RKO97392.1 - 5.6e-51 173.6 0.8 1e-50 172.7 0.8 1.4 1 0 0 1 1 1 1 BRO1-like domain Laminin_B PF00052.18 RKO97392.1 - 0.036 14.0 0.5 0.17 11.8 0.1 2.2 2 0 0 2 2 2 0 Laminin B (Domain IV) DUF4396 PF14342.6 RKO97392.1 - 0.12 12.8 1.0 0.26 11.6 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) TPR_12 PF13424.6 RKO97392.1 - 9.2 6.6 8.3 9.2 6.6 0.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Cation_efflux PF01545.21 RKO97393.1 - 2.2e-21 76.5 17.4 2.7e-21 76.2 17.4 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 RKO97393.1 - 2.4e-11 43.6 0.0 4.5e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Mo25 PF08569.11 RKO97393.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Mo25-like RhodobacterPufX PF11511.8 RKO97393.1 - 0.16 11.6 0.8 0.62 9.7 0.8 2.0 1 0 0 1 1 1 0 Intrinsic membrane protein PufX Alpha-amylase_C PF02806.18 RKO97394.1 - 3.4e-24 85.2 0.0 8.6e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 RKO97394.1 - 3.9e-17 62.4 0.0 7.9e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 RKO97394.1 - 5.1e-15 55.9 0.1 4.2e-12 46.3 0.0 2.2 1 1 0 2 2 2 2 Alpha amylase, catalytic domain zf-C2H2_aberr PF17017.5 RKO97396.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.1 1 0 0 1 1 1 0 Aberrant zinc-finger Cyclin PF08613.11 RKO97397.1 - 2.2e-20 73.7 0.1 2.4e-20 73.5 0.1 1.0 1 0 0 1 1 1 1 Cyclin Cyclin PF08613.11 RKO97398.1 - 2.1e-09 37.9 0.0 2.2e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin DUF1996 PF09362.10 RKO97399.1 - 1e-53 182.8 0.0 1.1e-53 182.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Hydrophobin PF01185.18 RKO97400.1 - 3.6e-06 27.5 8.0 5.6e-06 26.9 7.8 1.4 1 1 0 1 1 1 1 Fungal hydrophobin SH3_9 PF14604.6 RKO97401.1 - 4.3e-05 23.3 0.0 7.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain WSC PF01822.19 RKO97401.1 - 5.5e-05 23.3 8.5 9.7e-05 22.5 8.5 1.4 1 0 0 1 1 1 1 WSC domain SH3_2 PF07653.17 RKO97401.1 - 0.00063 19.4 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO97401.1 - 0.00089 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain DUF1180 PF06679.12 RKO97401.1 - 0.027 14.9 7.4 0.046 14.1 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1180) DUF4690 PF15756.5 RKO97401.1 - 0.061 13.9 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Pkinase PF00069.25 RKO97402.1 - 1.4e-43 149.2 0.0 1.5e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97402.1 - 3.2e-15 56.1 0.0 4.1e-15 55.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97402.1 - 4e-05 23.1 0.0 5.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKO97402.1 - 0.00036 20.0 0.0 0.00053 19.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CIA30 PF08547.12 RKO97403.1 - 6.5e-37 127.0 0.0 8.1e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 RKO97403.1 - 0.0012 18.9 0.1 0.0018 18.2 0.1 1.3 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain NGP1NT PF08153.12 RKO97404.1 - 5.2e-49 165.7 0.1 6.7e-49 165.4 0.1 1.1 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 RKO97404.1 - 0.098 12.7 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-H2C2_2 PF13465.6 RKO97405.1 - 9.4e-11 41.6 21.4 1e-06 28.9 2.2 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKO97405.1 - 7.1e-10 38.8 27.1 0.0011 19.3 7.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 RKO97405.1 - 4.2e-06 26.9 10.1 0.095 13.0 3.0 3.1 2 1 1 3 3 3 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 RKO97405.1 - 5.8e-06 26.7 24.5 0.033 15.0 7.1 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 RKO97405.1 - 0.00067 20.0 11.3 0.99 9.9 1.7 3.2 3 0 0 3 3 3 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 RKO97405.1 - 0.0012 18.8 22.8 0.39 10.8 0.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-FCS PF06467.14 RKO97405.1 - 0.02 14.8 1.4 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif zf_ZIC PF18366.1 RKO97405.1 - 0.32 11.1 5.7 1.4 9.1 0.1 2.4 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-H2C2_5 PF13909.6 RKO97405.1 - 0.97 9.3 16.4 6.5 6.6 0.1 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 RKO97405.1 - 3.6 8.1 11.8 9.3 6.8 5.9 3.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger PSP1 PF04468.12 RKO97406.1 - 9.3e-34 115.6 3.2 1.5e-33 114.9 3.2 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Cyclin PF08613.11 RKO97409.1 - 0.0041 17.5 0.7 0.022 15.1 0.0 2.3 1 1 2 3 3 3 1 Cyclin YbgS PF13985.6 RKO97409.1 - 9.3 6.6 7.9 1.1 9.6 2.4 2.1 2 0 0 2 2 2 0 YbgS-like protein Sel1 PF08238.12 RKO97410.1 - 5.7e-18 64.9 17.8 5.1e-05 23.8 0.0 5.3 5 1 0 5 5 5 4 Sel1 repeat Strabismus PF06638.11 RKO97410.1 - 0.23 10.1 0.0 0.3 9.7 0.0 1.1 1 0 0 1 1 1 0 Strabismus protein CAP PF00188.26 RKO97411.1 - 8.9e-15 55.6 0.1 1.1e-14 55.4 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family EF-hand_1 PF00036.32 RKO97413.1 - 1.1e-12 46.5 11.8 3.5e-07 29.3 2.1 4.9 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 RKO97413.1 - 8.7e-11 40.9 9.7 1.2e-07 31.1 1.2 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 RKO97413.1 - 4.3e-10 39.9 7.8 1.7e-06 28.4 0.5 2.6 2 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 RKO97413.1 - 5.7e-10 38.9 5.0 0.00012 21.9 0.4 3.8 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 RKO97413.1 - 4.8e-06 25.8 9.9 0.00012 21.4 2.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_11 PF08976.11 RKO97413.1 - 0.0016 19.3 0.1 0.024 15.5 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain SurA_N_2 PF13623.6 RKO97413.1 - 0.0038 17.1 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 2 SurA N-terminal domain Syntaxin PF00804.25 RKO97413.1 - 0.049 13.3 0.1 2.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Syntaxin EF-hand_9 PF14658.6 RKO97413.1 - 0.054 13.8 1.3 0.7 10.3 0.1 2.6 3 1 0 3 3 3 0 EF-hand domain UPF0154 PF03672.13 RKO97413.1 - 0.13 12.3 0.0 0.64 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF1754 PF08555.10 RKO97414.1 - 4.5e-09 37.0 0.5 4.5e-09 37.0 0.5 1.7 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Integrin_b_cyt PF08725.11 RKO97415.1 - 0.0002 21.0 0.1 0.0002 21.0 0.1 2.6 2 1 0 2 2 2 1 Integrin beta cytoplasmic domain DUF5631 PF18645.1 RKO97418.1 - 0.055 13.8 0.2 13 6.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5631) YEATS PF03366.16 RKO97419.1 - 2.6e-12 46.5 0.0 4.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family SDA1 PF05285.12 RKO97419.1 - 2 7.7 11.2 2.8 7.3 11.2 1.2 1 0 0 1 1 1 0 SDA1 DEAD PF00270.29 RKO97420.1 - 1.3e-47 161.9 0.0 2.4e-47 161.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO97420.1 - 8.1e-25 87.3 0.0 1.2e-23 83.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 RKO97420.1 - 1e-15 57.7 0.1 2e-15 56.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 RKO97420.1 - 6.5e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RKO97420.1 - 9.2e-05 21.8 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SH3_2 PF07653.17 RKO97421.1 - 0.091 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain PAT1 PF09770.9 RKO97421.1 - 3.3 5.9 12.0 4.1 5.5 12.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 RKO97421.1 - 3.9 7.4 15.7 5.9 6.8 15.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit B9-C2 PF07162.11 RKO97422.1 - 4.5e-43 147.4 0.1 5e-43 147.2 0.1 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein TRAM_LAG1_CLN8 PF03798.16 RKO97423.1 - 1.2e-35 123.1 15.0 1.3e-35 122.9 15.0 1.0 1 0 0 1 1 1 1 TLC domain NAD_binding_2 PF03446.15 RKO97426.1 - 3.4e-38 131.3 0.7 5.6e-38 130.6 0.7 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 RKO97426.1 - 1.4e-29 102.8 0.0 3e-29 101.7 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Sacchrp_dh_NADP PF03435.18 RKO97426.1 - 0.0076 16.5 0.3 0.4 11.0 0.3 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 2-Hacid_dh_C PF02826.19 RKO97426.1 - 0.035 13.5 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 RKO97426.1 - 0.067 13.8 0.0 0.15 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-C2H2 PF00096.26 RKO97427.1 - 2.3e-13 49.8 18.7 0.00027 21.2 5.7 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO97427.1 - 3.1e-08 33.8 17.6 0.014 16.2 0.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKO97427.1 - 2.3e-05 24.6 6.7 0.0024 18.2 0.9 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf_UBZ PF18439.1 RKO97427.1 - 0.0021 17.6 2.7 0.33 10.6 0.1 3.1 3 0 0 3 3 3 1 Ubiquitin-Binding Zinc Finger zf_C2H2_ZHX PF18387.1 RKO97427.1 - 0.0044 16.6 3.3 0.14 11.8 0.6 2.4 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain TFIIS_C PF01096.18 RKO97427.1 - 0.014 15.2 3.2 1.6 8.6 0.7 2.4 2 1 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-met PF12874.7 RKO97427.1 - 0.019 15.3 2.1 0.52 10.8 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 RKO97427.1 - 0.039 13.7 4.8 0.039 13.7 4.8 3.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zinc_ribbon_4 PF13717.6 RKO97427.1 - 0.059 13.3 6.0 0.43 10.5 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.19 RKO97427.1 - 0.071 13.1 0.6 0.079 13.0 0.6 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA OrfB_Zn_ribbon PF07282.11 RKO97427.1 - 0.076 12.9 3.0 4.6 7.2 0.1 2.2 1 1 1 2 2 2 0 Putative transposase DNA-binding domain CpXC PF14353.6 RKO97427.1 - 0.12 12.5 2.0 6.2 6.9 0.2 2.3 1 1 1 2 2 2 0 CpXC protein zinc_ribbon_13 PF09855.9 RKO97427.1 - 0.15 12.3 1.9 13 6.1 0.5 2.4 2 1 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn-ribbon_8 PF09723.10 RKO97427.1 - 0.15 12.2 4.7 4.6 7.4 3.8 2.7 1 1 1 2 2 2 0 Zinc ribbon domain Elf1 PF05129.13 RKO97427.1 - 0.16 12.0 0.5 0.16 12.0 0.5 2.1 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_jaz PF12171.8 RKO97427.1 - 0.3 11.4 6.1 7.1 7.0 0.8 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKO97427.1 - 0.32 11.0 8.7 5.4 7.1 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-LYAR PF08790.11 RKO97427.1 - 0.49 10.3 9.9 4.6 7.2 2.2 3.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger DUF2256 PF10013.9 RKO97427.1 - 0.58 10.3 6.4 1.8 8.8 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Pkinase PF00069.25 RKO97429.1 - 1e-54 185.7 0.0 1.2e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97429.1 - 3.3e-29 102.0 0.0 4.5e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97429.1 - 3.4e-10 39.7 0.0 6.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKO97429.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 RKO97429.1 - 0.13 12.2 0.1 1.5 8.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Arrestin_C PF02752.22 RKO97431.1 - 0.00027 21.4 0.0 0.00068 20.1 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain OCRE PF17780.1 RKO97431.1 - 0.009 16.0 0.1 0.027 14.5 0.0 1.9 2 0 0 2 2 2 1 OCRE domain Arrestin_N PF00339.29 RKO97431.1 - 0.017 15.2 0.0 0.047 13.7 0.0 1.7 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Dynein_light PF01221.18 RKO97431.1 - 0.54 10.6 2.4 1.1 9.6 2.4 1.4 1 0 0 1 1 1 0 Dynein light chain type 1 NO_synthase PF02898.15 RKO97432.1 - 3.3e-120 401.4 0.0 3.7e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Nitric oxide synthase, oxygenase domain NAD_binding_1 PF00175.21 RKO97433.1 - 2.2e-15 57.2 0.0 2.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain OPT PF03169.15 RKO97434.1 - 3.3e-122 409.2 51.3 3.8e-122 409.0 51.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein MerE PF05052.12 RKO97434.1 - 3.1 7.8 7.7 1 9.4 3.6 2.3 2 0 0 2 2 2 0 MerE protein Rrn6 PF10214.9 RKO97435.1 - 0.1 11.0 4.6 0.13 10.7 4.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SasG_E PF17041.5 RKO97436.1 - 0.036 14.1 0.1 0.11 12.5 0.1 1.8 1 0 0 1 1 1 0 E domain NFACT-R_1 PF05670.13 RKO97437.1 - 7.9e-37 126.2 0.0 1.4e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain Phage_Mu_F PF04233.14 RKO97437.1 - 0.0057 17.4 2.6 0.0089 16.8 2.6 1.4 1 0 0 1 1 1 1 Phage Mu protein F like protein Prominin PF05478.11 RKO97437.1 - 0.032 12.2 1.4 0.035 12.1 1.4 1.0 1 0 0 1 1 1 0 Prominin DUF3027 PF11228.8 RKO97437.1 - 0.09 12.8 0.4 0.13 12.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3027) DUF719 PF05334.13 RKO97437.1 - 0.18 12.0 3.9 0.3 11.3 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF719) DUF4337 PF14235.6 RKO97437.1 - 0.64 10.1 4.5 0.53 10.4 3.5 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) UPF0242 PF06785.11 RKO97438.1 - 2 8.5 10.7 2.8 8.0 10.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PIEZO PF15917.5 RKO97438.1 - 3.9 6.9 6.5 5.6 6.4 6.5 1.3 1 0 0 1 1 1 0 Piezo Tetraspanin PF00335.20 RKO97439.1 - 1.1e-27 97.3 10.3 1.3e-27 97.0 10.3 1.1 1 0 0 1 1 1 1 Tetraspanin family Spore_YhaL PF14147.6 RKO97439.1 - 0.15 11.8 0.1 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 Sporulation protein YhaL DUF2569 PF10754.9 RKO97439.1 - 0.98 9.9 5.8 1.2 9.6 4.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Mob1_phocein PF03637.17 RKO97440.1 - 7e-56 188.9 0.0 8.3e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family AZUL PF16558.5 RKO97440.1 - 0.095 13.0 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A SIS PF01380.22 RKO97441.1 - 8.7e-64 213.2 0.4 2.3e-32 111.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 RKO97441.1 - 3.6e-17 62.8 0.0 8.5e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 RKO97441.1 - 1.2e-12 47.8 0.0 3.3e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 RKO97441.1 - 0.0001 21.3 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 RKO97441.1 - 0.0069 16.4 0.0 0.019 14.9 0.0 1.8 1 0 0 1 1 1 1 SIS domain GATase_2 PF00310.21 RKO97441.1 - 0.082 11.6 0.0 0.38 9.4 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferases class-II Ysc84 PF04366.12 RKO97442.1 - 8.8e-44 148.3 0.1 1.1e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator RRM_1 PF00076.22 RKO97445.1 - 5.5e-24 83.8 0.1 2.3e-12 46.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 RKO97445.1 - 8.5e-06 25.8 0.0 0.00037 20.5 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif RRM_9 PF18444.1 RKO97445.1 - 0.044 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 RKO97445.1 - 0.16 11.8 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4874 PF16173.5 RKO97446.1 - 5.6e-11 42.4 0.0 7.9e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) DUF4832 PF16116.5 RKO97446.1 - 0.00023 21.1 0.1 0.0004 20.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4832) bZIP_1 PF00170.21 RKO97447.1 - 1.1e-06 28.6 6.3 2.3e-06 27.6 6.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 RKO97447.1 - 9.9e-06 25.5 9.1 2.4e-05 24.3 9.1 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Histone_HNS PF00816.21 RKO97447.1 - 0.93 10.4 5.2 0.91 10.4 0.5 2.4 2 0 0 2 2 2 0 H-NS histone family bZIP_Maf PF03131.17 RKO97447.1 - 1.3 9.6 14.5 0.1 13.1 4.9 2.4 2 0 0 2 2 2 0 bZIP Maf transcription factor Occludin_ELL PF07303.13 RKO97447.1 - 3.3 8.5 8.0 0.35 11.6 2.3 2.1 3 0 0 3 3 3 0 Occludin homology domain AAA_6 PF12774.7 RKO97448.1 - 1.7e-158 526.8 0.0 2.8e-157 522.8 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKO97448.1 - 3.1e-134 448.0 5.3 3.1e-134 448.0 5.3 2.2 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_7 PF12775.7 RKO97448.1 - 4.9e-72 241.2 2.8 5e-69 231.4 0.2 3.8 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_5 PF07728.14 RKO97448.1 - 3.5e-19 69.2 0.0 1e-06 28.8 0.0 5.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKO97448.1 - 1.6e-18 67.0 0.2 7.1e-18 64.9 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RKO97448.1 - 1.7e-16 60.3 0.0 1.2e-15 57.5 0.0 2.5 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 RKO97448.1 - 3.3e-08 34.0 0.1 0.064 13.7 0.0 3.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKO97448.1 - 5.4e-05 23.5 0.4 1.2 9.4 0.0 4.2 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 RKO97448.1 - 0.00013 22.3 0.0 1.8 9.0 0.0 4.0 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 RKO97448.1 - 0.00029 21.3 0.2 4.1 7.7 0.0 4.7 4 1 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.6 RKO97448.1 - 0.0056 17.2 0.0 0.82 10.2 0.0 3.8 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 RKO97448.1 - 0.019 14.7 0.4 1.9 8.1 0.3 3.0 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 RKO97448.1 - 0.048 12.7 0.0 0.23 10.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Latarcin PF10279.9 RKO97448.1 - 0.081 13.3 1.3 20 5.7 0.6 3.0 2 0 0 2 2 2 0 Latarcin precursor AAA_33 PF13671.6 RKO97448.1 - 0.089 13.0 3.1 45 4.2 0.0 4.7 4 1 0 4 4 4 0 AAA domain AAA_24 PF13479.6 RKO97448.1 - 0.11 12.2 1.9 25 4.5 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 RKO97448.1 - 0.25 10.9 2.3 1 8.9 0.0 3.2 4 0 0 4 4 4 0 AAA domain DHHC PF01529.20 RKO97449.1 - 4.1e-33 114.3 6.6 4.1e-33 114.3 6.6 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 RKO97449.1 - 6.3e-21 74.8 1.7 7.9e-12 45.6 0.1 3.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 RKO97449.1 - 3.5e-15 55.9 5.1 1.5e-05 25.2 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 RKO97449.1 - 2.7e-13 50.1 1.0 5e-06 27.0 0.3 3.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 RKO97449.1 - 8.4e-11 41.1 1.2 0.031 14.8 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 RKO97449.1 - 2.1e-10 40.5 6.2 0.044 14.2 0.6 4.7 5 0 0 5 5 5 3 Ankyrin repeat HscB_4_cys PF18256.1 RKO97449.1 - 1.8 8.4 6.2 3.9 7.4 0.3 3.0 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif LSM PF01423.22 RKO97450.1 - 1.7e-18 66.1 0.1 1.9e-18 65.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKO97450.1 - 0.068 13.3 0.0 0.075 13.2 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 RKO97450.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Hfq protein Ribosomal_L26 PF16906.5 RKO97451.1 - 1.1e-31 109.2 1.3 1.3e-31 108.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 RKO97451.1 - 2.8e-08 33.4 1.8 6.4e-08 32.3 1.8 1.6 1 0 0 1 1 1 1 KOW motif Adeno_VII PF03228.14 RKO97451.1 - 0.0036 17.9 0.4 0.0051 17.4 0.3 1.4 1 1 0 1 1 1 1 Adenoviral core protein VII Glyoxalase PF00903.25 RKO97452.1 - 2.4e-17 63.3 0.0 3.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 RKO97452.1 - 4.3e-08 33.4 0.0 5.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 RKO97452.1 - 0.0066 16.4 0.0 0.0091 15.9 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 RKO97452.1 - 0.01 16.6 0.0 0.016 16.0 0.0 1.2 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase_3 PF13468.6 RKO97452.1 - 0.082 13.0 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain DUF21 PF01595.20 RKO97453.1 - 2.1e-32 112.2 0.0 3e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 RKO97453.1 - 3e-05 24.4 0.4 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 1 CBS domain ATG16 PF08614.11 RKO97454.1 - 0.00011 22.4 42.7 2.2 8.5 30.7 4.4 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 RKO97454.1 - 0.014 15.4 2.0 0.014 15.4 2.0 5.5 4 1 2 7 7 6 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 RKO97454.1 - 0.09 12.0 10.8 2.7 7.2 0.1 2.4 2 0 0 2 2 2 0 TMPIT-like protein DUF1664 PF07889.12 RKO97454.1 - 0.12 12.5 18.6 0.9 9.6 6.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 RKO97454.1 - 0.13 11.5 39.3 0.25 10.6 0.0 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3450) Spc7 PF08317.11 RKO97454.1 - 0.15 10.9 36.9 0.19 10.5 17.2 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein TSC22 PF01166.18 RKO97454.1 - 0.16 12.3 9.6 11 6.5 0.1 4.7 4 1 0 4 4 4 0 TSC-22/dip/bun family DUF948 PF06103.11 RKO97454.1 - 0.34 11.2 11.8 0.53 10.6 0.8 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 RKO97454.1 - 0.61 9.6 35.3 4.8 6.7 0.2 3.8 2 1 2 4 4 4 0 Intermediate filament protein KASH_CCD PF14662.6 RKO97454.1 - 0.87 9.4 36.0 0.39 10.5 20.4 3.1 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 RKO97454.1 - 0.93 9.8 19.4 1.5 9.2 2.2 3.7 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FapA PF03961.13 RKO97454.1 - 1 7.9 13.2 0.071 11.7 3.9 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A Tropomyosin_1 PF12718.7 RKO97454.1 - 1.4 9.1 35.5 0.048 13.8 2.3 3.7 3 1 0 3 3 3 0 Tropomyosin like AAA_13 PF13166.6 RKO97454.1 - 2.1 6.9 20.5 5.4 5.5 0.8 2.2 1 1 0 2 2 2 0 AAA domain YabA PF06156.13 RKO97454.1 - 2.1 9.0 19.9 4.4 8.0 0.4 4.0 3 1 1 4 4 4 0 Initiation control protein YabA HMMR_N PF15905.5 RKO97454.1 - 2.4 7.6 30.1 0.53 9.7 23.3 2.6 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal DUF4407 PF14362.6 RKO97454.1 - 3.2 7.0 32.7 0.55 9.5 4.2 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nsp1_C PF05064.13 RKO97454.1 - 3.3 7.5 25.2 4.9 7.0 7.5 4.1 2 1 2 4 4 4 0 Nsp1-like C-terminal region Phage_GPO PF05929.11 RKO97454.1 - 3.8 7.0 25.9 2 7.9 4.8 3.1 2 1 1 3 3 3 0 Phage capsid scaffolding protein (GPO) serine peptidase Fib_alpha PF08702.10 RKO97454.1 - 4 7.6 19.4 0.49 10.6 8.9 3.2 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family MAD PF05557.13 RKO97454.1 - 4.3 5.6 34.1 0.2 10.0 26.3 2.3 2 1 0 2 2 2 0 Mitotic checkpoint protein FliD_C PF07195.12 RKO97454.1 - 4.4 6.6 12.0 5.9 6.2 3.5 3.0 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 C-terminus DUF3818 PF12825.7 RKO97454.1 - 5 6.0 8.0 8.7 5.2 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF4200 PF13863.6 RKO97454.1 - 5.8 7.3 29.6 2.9 8.3 9.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) KxDL PF10241.9 RKO97454.1 - 6.5 7.1 23.5 7 7.0 0.1 4.7 3 1 2 5 5 5 0 Uncharacterized conserved protein SNRNP27 PF08648.12 RKO97456.1 - 1.6e-24 85.7 0.1 1.9e-24 85.5 0.1 1.0 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins AMP-binding PF00501.28 RKO97457.1 - 4.3e-85 285.9 0.0 5.9e-85 285.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKO97457.1 - 0.00067 20.6 0.0 0.0025 18.7 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 RKO97458.1 - 4.7e-28 96.8 8.8 4.6e-06 27.3 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.8 RKO97458.1 - 2.5e-10 39.7 0.9 0.017 13.8 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 RKO97458.1 - 0.009 14.8 0.0 5.2 5.7 0.0 3.1 1 1 0 2 2 2 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 RKO97458.1 - 0.015 15.6 0.1 0.13 12.6 0.0 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RKO97458.1 - 0.018 15.5 0.7 3.5 8.2 0.1 3.1 3 0 0 3 3 3 0 PQQ-like domain Hira PF07569.11 RKO97458.1 - 0.051 13.3 0.0 2.4 7.8 0.0 2.5 2 1 0 2 2 2 0 TUP1-like enhancer of split JHD PF17811.1 RKO97459.1 - 5.4e-07 30.1 0.1 8.8e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 RKO97459.1 - 3.9e-06 27.3 0.1 0.00016 22.1 0.1 2.4 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 RKO97459.1 - 1.7e-05 24.7 0.0 6.5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain zf-C2H2_4 PF13894.6 RKO97460.1 - 6.5e-12 45.2 6.7 1.8e-05 25.2 0.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RKO97460.1 - 2.7e-11 43.3 8.1 8.4e-06 26.0 0.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RKO97460.1 - 1e-06 28.6 3.1 0.0057 16.6 0.1 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKO97460.1 - 9.9e-06 25.7 0.9 0.11 12.8 0.0 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 RKO97460.1 - 3.1e-05 24.2 0.6 4.9e-05 23.5 0.6 1.3 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RKO97460.1 - 7.1e-05 23.1 4.2 0.011 16.1 0.1 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.7 RKO97460.1 - 0.0002 21.6 1.2 0.14 12.6 0.2 2.2 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RKO97460.1 - 0.0002 20.9 0.4 0.067 12.8 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 RKO97460.1 - 0.00054 20.4 0.5 0.0054 17.1 0.1 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-TRAF PF02176.18 RKO97460.1 - 0.0013 19.4 0.6 0.0017 19.0 0.6 1.2 1 0 0 1 1 1 1 TRAF-type zinc finger Nudix_N_2 PF14803.6 RKO97460.1 - 0.0018 18.1 1.1 0.013 15.4 1.1 2.1 1 1 0 1 1 1 1 Nudix N-terminal zf-C2H2_2 PF12756.7 RKO97460.1 - 0.0021 18.3 0.5 1.9 8.9 0.0 2.0 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 RKO97460.1 - 0.0041 17.1 4.3 0.74 9.9 0.3 2.2 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_8 PF15909.5 RKO97460.1 - 0.014 15.7 1.1 0.016 15.5 1.1 1.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 RKO97460.1 - 0.018 14.6 0.5 3.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf_C2H2_6 PF18450.1 RKO97460.1 - 0.022 14.5 1.0 0.047 13.4 1.0 1.5 1 0 0 1 1 1 0 Zinc Finger domain PyrI_C PF02748.15 RKO97460.1 - 0.029 14.3 0.7 0.5 10.3 0.0 2.1 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-LYAR PF08790.11 RKO97460.1 - 0.032 14.1 1.2 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HC_2 PF13913.6 RKO97460.1 - 0.034 14.1 8.8 0.14 12.1 1.6 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 RKO97460.1 - 0.034 14.2 2.3 0.077 13.1 1.2 1.9 1 1 1 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 RKO97460.1 - 0.037 14.0 3.7 3.2 7.8 1.0 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2688 PF10892.8 RKO97460.1 - 0.039 13.4 0.8 0.065 12.7 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) zf-C2H2_3rep PF18868.1 RKO97460.1 - 0.043 14.5 2.8 4.3 8.0 0.8 2.0 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats HNH PF01844.23 RKO97460.1 - 0.053 13.7 0.5 4 7.7 0.1 2.2 2 0 0 2 2 2 0 HNH endonuclease zf-Mss51 PF13824.6 RKO97460.1 - 0.11 12.6 2.4 2.5 8.3 0.1 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 TF_Zn_Ribbon PF08271.12 RKO97460.1 - 0.12 11.9 3.0 0.76 9.3 3.2 2.0 1 1 2 3 3 3 0 TFIIB zinc-binding Actin_micro PF17003.5 RKO97460.1 - 0.22 10.7 0.6 5.7 6.0 0.1 2.0 1 1 1 2 2 2 0 Putative actin-like family zf-H2C2_5 PF13909.6 RKO97460.1 - 0.32 10.8 0.3 0.32 10.8 0.3 2.5 3 0 0 3 3 2 0 C2H2-type zinc-finger domain zinc_ribbon_2 PF13240.6 RKO97460.1 - 0.84 9.4 5.0 4.2 7.2 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 RKO97460.1 - 1.2 9.3 5.5 12 6.0 0.8 2.5 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_11 PF16622.5 RKO97460.1 - 3.6 7.4 8.0 2.8 7.8 1.7 2.4 2 1 0 2 2 2 0 zinc-finger C2H2-type DUF3336 PF11815.8 RKO97461.1 - 3.1e-34 117.7 1.4 5.8e-34 116.8 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 RKO97461.1 - 8.1e-22 78.4 0.0 1.7e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase EF-hand_1 PF00036.32 RKO97462.1 - 4e-23 79.2 8.3 8.5e-07 28.1 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 RKO97462.1 - 1.5e-22 79.8 8.5 4e-13 49.6 0.2 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 RKO97462.1 - 8.3e-22 75.2 3.1 5.5e-06 25.9 0.0 4.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 RKO97462.1 - 6e-16 57.1 5.0 6.6e-05 22.2 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 RKO97462.1 - 3.1e-12 46.1 6.6 1.2e-05 25.0 0.6 4.2 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 RKO97462.1 - 1.1e-06 28.5 6.1 0.42 10.6 0.3 3.9 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 RKO97462.1 - 0.0019 18.5 2.7 1.1 9.5 0.5 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1707 PF08044.11 RKO97462.1 - 0.057 13.5 0.1 7.9 6.6 0.0 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF1707) EF-hand_9 PF14658.6 RKO97462.1 - 0.11 12.9 0.6 1.5 9.2 0.0 2.8 3 1 0 3 3 3 0 EF-hand domain Pan3_PK PF18101.1 RKO97462.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Pan3 Pseudokinase domain Pkinase PF00069.25 RKO97464.1 - 1.5e-64 218.0 0.0 1.7e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97464.1 - 9.7e-19 67.7 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 RKO97464.1 - 2.1e-07 31.1 0.2 7.2e-06 26.1 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RKO97464.1 - 0.0059 15.4 0.0 0.012 14.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 RKO97464.1 - 0.034 13.7 0.1 0.077 12.6 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 RKO97464.1 - 0.035 13.4 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cwf_Cwc_15 PF04889.12 RKO97465.1 - 0.038 13.7 9.1 0.069 12.9 9.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 RKO97465.1 - 0.6 10.4 6.6 1.8 8.8 6.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) FAM176 PF14851.6 RKO97465.1 - 1.8 8.2 3.2 3.6 7.2 3.2 1.5 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 RKO97465.1 - 1.9 7.7 9.7 3.3 6.9 9.7 1.3 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 RKO97465.1 - 8.6 4.3 11.1 11 3.9 11.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Radical_SAM_C PF16199.5 RKO97466.1 - 1.2e-11 44.4 0.1 2e-11 43.8 0.1 1.3 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Acetyltransf_1 PF00583.25 RKO97466.1 - 3.1e-10 40.3 0.0 3.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RKO97466.1 - 9.8e-06 25.5 0.0 3.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RKO97466.1 - 0.01 16.3 0.0 0.015 15.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.25 RKO97467.1 - 1.4e-67 227.8 0.0 1.7e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97467.1 - 1.4e-29 103.2 0.0 1.8e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97467.1 - 1.6e-10 40.8 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKO97467.1 - 0.003 17.0 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKO97467.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain 5-FTHF_cyc-lig PF01812.20 RKO97468.1 - 1.5e-30 106.4 0.0 2.1e-29 102.7 0.0 2.0 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family SNF2_N PF00176.23 RKO97469.1 - 1.2e-25 90.0 0.0 1.9e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 RKO97469.1 - 2e-14 53.8 0.0 4.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO97469.1 - 0.00029 20.9 0.0 0.038 14.0 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 RKO97469.1 - 0.0015 17.8 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 RKO97469.1 - 0.011 15.5 0.1 0.19 11.5 0.1 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase FH2 PF02181.23 RKO97470.1 - 8.1e-44 150.2 0.0 1.1e-42 146.5 0.0 2.0 1 1 0 1 1 1 1 Formin Homology 2 Domain ProRS-C_1 PF09180.11 RKO97471.1 - 1e-21 76.9 0.5 2.2e-21 75.8 0.5 1.5 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 RKO97471.1 - 2.9e-20 73.0 0.0 7.2e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RKO97471.1 - 4.8e-15 55.5 0.0 9.4e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain COX6B PF02297.17 RKO97472.1 - 1.8e-18 66.5 8.5 2.1e-18 66.3 8.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CX9C PF16860.5 RKO97472.1 - 0.0043 17.0 3.7 0.0073 16.3 3.7 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, APOBEC_C PF05240.14 RKO97472.1 - 0.015 15.2 0.4 0.026 14.5 0.4 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain IGR PF09597.10 RKO97473.1 - 1.6e-19 69.7 0.7 1.2e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 IGR protein motif Myb_DNA-bind_7 PF15963.5 RKO97474.1 - 0.0072 16.2 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Myb DNA-binding like PI3K_1B_p101 PF10486.9 RKO97474.1 - 0.12 10.2 3.0 0.17 9.6 3.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Rhabdo_ncap PF00945.18 RKO97474.1 - 0.18 10.7 0.8 0.32 9.8 0.8 1.4 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Mitofilin PF09731.9 RKO97474.1 - 7.5 5.3 8.2 0.73 8.6 3.7 1.5 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Nipped-B_C PF12830.7 RKO97475.1 - 1.1e-32 113.6 0.0 3.7e-32 111.8 0.0 2.0 1 0 0 1 1 1 1 Sister chromatid cohesion C-terminus RNase_H2_suC PF08615.11 RKO97475.1 - 4.2e-10 39.9 0.1 4.1e-09 36.7 0.0 2.6 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Cohesin_HEAT PF12765.7 RKO97475.1 - 1.6e-06 28.3 7.6 2e-06 28.0 1.0 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd3 PF12719.7 RKO97475.1 - 4e-05 22.9 0.7 0.0056 15.9 0.1 2.8 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 RKO97475.1 - 0.0074 14.9 0.9 0.051 12.1 0.1 2.5 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 RKO97475.1 - 0.048 13.7 0.4 23 5.0 0.1 3.7 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 RKO97475.1 - 0.071 13.4 15.3 14 6.3 0.0 6.8 7 0 0 7 7 7 0 HEAT repeat HEAT_2 PF13646.6 RKO97475.1 - 0.25 11.8 8.1 3.3 8.1 0.4 5.3 5 0 0 5 5 5 0 HEAT repeats G10 PF01125.17 RKO97476.1 - 1.9e-63 212.6 1.7 2.1e-63 212.5 1.7 1.0 1 0 0 1 1 1 1 G10 protein Ribophorin_I PF04597.14 RKO97477.1 - 2e-81 274.4 0.0 2.4e-81 274.2 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I VWA_CoxE PF05762.14 RKO97477.1 - 0.0059 16.0 0.1 0.0093 15.4 0.1 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Iso_dh PF00180.20 RKO97478.1 - 2e-121 405.4 0.0 2.4e-121 405.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 RKO97479.1 - 2.5e-59 200.8 0.0 1.1e-51 175.8 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97479.1 - 7.8e-37 127.0 0.1 3.1e-31 108.6 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 RKO97479.1 - 8.6e-08 31.8 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKO97479.1 - 1.2e-06 28.7 0.5 4.4e-05 23.5 0.5 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 RKO97479.1 - 0.001 18.7 0.1 0.0015 18.1 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 RKO97479.1 - 0.015 14.7 0.3 0.046 13.1 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 RKO97479.1 - 0.015 14.9 0.1 0.022 14.4 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 RKO97479.1 - 0.019 13.7 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF5525 PF17663.1 RKO97479.1 - 0.021 13.0 1.1 0.027 12.6 1.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5525) Haspin_kinase PF12330.8 RKO97479.1 - 0.039 12.9 0.1 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 RKO97479.1 - 0.12 11.2 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Bap31 PF05529.12 RKO97480.1 - 1.2e-09 38.1 1.4 7.1e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Bap31/Bap29 transmembrane region Ribosomal_L38e PF01781.18 RKO97481.1 - 2.9e-28 97.7 1.2 3.2e-28 97.6 1.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family PrmA PF06325.13 RKO97482.1 - 2e-12 47.1 0.3 2.6e-12 46.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 RKO97482.1 - 9.3e-10 38.3 0.2 6.2e-09 35.6 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 RKO97482.1 - 1.5e-06 28.8 0.1 3.3e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 RKO97482.1 - 9.1e-06 25.4 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 RKO97482.1 - 1.6e-05 24.7 0.0 2.5e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 RKO97482.1 - 0.00068 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 RKO97482.1 - 0.001 18.9 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 RKO97482.1 - 0.003 17.3 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 RKO97482.1 - 0.0053 16.5 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 RKO97482.1 - 0.0081 15.9 0.1 0.024 14.3 0.1 1.8 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_15 PF09445.10 RKO97482.1 - 0.052 13.1 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 RKO97482.1 - 0.097 13.3 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 RKO97482.1 - 0.15 11.4 0.2 0.27 10.5 0.2 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.7 RKO97482.1 - 0.18 11.7 0.1 0.29 11.1 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-LYAR PF08790.11 RKO97483.1 - 9.2e-16 57.4 10.0 1.8e-14 53.3 4.7 2.1 2 0 0 2 2 2 2 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 RKO97483.1 - 2.4e-05 23.8 2.2 0.043 13.4 0.4 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DM PF00751.18 RKO97483.1 - 0.052 13.5 5.4 0.045 13.7 4.6 1.4 1 1 0 1 1 1 0 DM DNA binding domain DUF2318 PF10080.9 RKO97483.1 - 0.16 12.1 3.9 1.4 9.0 0.5 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) zf-C2H2_4 PF13894.6 RKO97483.1 - 0.3 12.0 5.1 6 8.0 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Sin_N PF04801.13 RKO97484.1 - 1.8e-51 175.7 0.0 2.3e-51 175.4 0.0 1.0 1 0 0 1 1 1 1 Sin-like protein conserved region RNA_pol_Rpb8 PF03870.15 RKO97484.1 - 0.052 13.7 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb8 Metallophos PF00149.28 RKO97485.1 - 1.2e-36 127.1 0.1 1.6e-36 126.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 RKO97485.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Ribosomal_S17 PF00366.20 RKO97486.1 - 1e-27 96.0 0.9 1.8e-27 95.2 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S17_N PF16205.5 RKO97486.1 - 2.9e-24 85.2 0.5 2.9e-24 85.2 0.5 1.7 2 0 0 2 2 2 1 Ribosomal_S17 N-terminal PQQ_2 PF13360.6 RKO97487.1 - 4.5e-06 26.4 0.9 0.025 14.2 0.1 3.0 4 0 0 4 4 4 2 PQQ-like domain Metallophos PF00149.28 RKO97488.1 - 7.8e-37 127.8 0.1 1.2e-36 127.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RKO97488.1 - 3.6e-16 59.3 0.1 6.1e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 RKO97490.1 - 5.5e-70 235.8 0.0 6.7e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97490.1 - 1.2e-30 106.6 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97490.1 - 2.1e-07 30.5 0.1 2.5e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like C2 PF00168.30 RKO97490.1 - 6e-05 23.3 0.1 0.00012 22.4 0.1 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 RKO97490.1 - 0.00018 20.6 0.1 0.00024 20.2 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 RKO97490.1 - 0.00041 21.0 1.2 0.0011 19.6 1.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain FTA2 PF13095.6 RKO97490.1 - 0.0013 18.3 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 RKO97490.1 - 0.0058 16.6 0.1 0.035 14.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family MCM PF00493.23 RKO97491.1 - 6e-102 339.5 0.5 4.4e-101 336.6 0.0 2.5 3 0 0 3 3 3 1 MCM P-loop domain MCM_OB PF17207.3 RKO97491.1 - 3.4e-34 117.4 0.9 7.6e-34 116.3 0.9 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 RKO97491.1 - 1.2e-25 89.7 3.3 3.4e-25 88.3 3.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 RKO97491.1 - 1.6e-19 70.4 2.6 1.9e-19 70.1 0.7 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 RKO97491.1 - 1.1e-06 28.2 0.1 0.00021 20.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 RKO97491.1 - 1.5e-05 25.1 0.1 0.0002 21.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 RKO97491.1 - 0.00026 20.9 0.0 0.00092 19.1 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 RKO97491.1 - 0.018 14.8 0.0 0.7 9.6 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 RKO97491.1 - 2.2 8.6 4.9 3 8.2 0.1 3.3 3 1 0 3 3 3 0 AAA ATPase domain Complex1_LYR PF05347.15 RKO97492.1 - 1.2e-11 44.5 0.3 1.6e-11 44.1 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1087 PF06465.13 RKO97492.1 - 0.38 10.8 3.4 0.28 11.2 1.0 1.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1087) B56 PF01603.20 RKO97493.1 - 4.5e-191 635.3 3.1 5.1e-191 635.1 3.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) NAD1 PF18778.1 RKO97493.1 - 0.091 12.8 0.1 3 7.9 0.1 2.3 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 Ran_BP1 PF00638.18 RKO97494.1 - 1.1e-49 167.8 0.1 1.3e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 RKO97494.1 - 7.8e-05 22.6 0.0 0.00046 20.1 0.0 1.9 1 1 0 1 1 1 1 WH1 domain Chlorosome_CsmC PF11098.8 RKO97495.1 - 0.45 10.5 3.8 0.72 9.8 3.8 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF5536 PF17688.1 RKO97495.1 - 0.54 10.1 8.3 0.94 9.3 8.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5536) PHD PF00628.29 RKO97496.1 - 8.1e-08 32.0 8.4 9.8e-08 31.8 8.4 1.1 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 RKO97496.1 - 0.0041 16.6 1.7 0.0069 15.9 1.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 RKO97496.1 - 0.0085 16.3 4.4 0.01 16.1 4.4 1.3 1 1 0 1 1 1 1 PHD-like zinc-binding domain zf-C4pol PF14260.6 RKO97496.1 - 0.092 13.2 1.2 0.092 13.2 1.2 2.0 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta CorA PF01544.18 RKO97497.1 - 4.1e-51 174.0 2.0 5e-51 173.7 2.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Plasmid_stab_B PF10784.9 RKO97497.1 - 0.035 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 Plasmid stability protein LTV PF04180.14 RKO97498.1 - 3.1e-35 122.7 18.7 2.1e-33 116.6 12.4 2.6 2 1 0 2 2 2 2 Low temperature viability protein Med10 PF09748.9 RKO97498.1 - 0.52 10.3 3.8 0.98 9.4 0.3 2.9 2 1 1 3 3 3 0 Transcription factor subunit Med10 of Mediator complex U1snRNP70_N PF12220.8 RKO97498.1 - 1.3 9.7 14.0 0.51 11.0 1.0 3.8 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-CCCH_4 PF18044.1 RKO97499.1 - 5.2e-05 22.9 3.2 8.5e-05 22.2 3.2 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger PAM2 PF07145.15 RKO97499.1 - 7.7e-05 22.1 2.6 0.18 11.6 0.4 2.7 2 0 0 2 2 2 2 Ataxin-2 C-terminal region zf-CCCH_2 PF14608.6 RKO97499.1 - 0.00022 21.6 5.2 0.00038 20.8 5.2 1.4 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 RKO97499.1 - 0.00069 19.5 2.8 0.0012 18.7 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TRAP_alpha PF03896.16 RKO97499.1 - 0.0032 16.7 0.2 0.0069 15.6 0.2 1.5 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit zf_CCCH_4 PF18345.1 RKO97499.1 - 0.023 14.7 2.5 0.043 13.9 2.5 1.4 1 0 0 1 1 1 0 Zinc finger domain Proteasome PF00227.26 RKO97500.1 - 1.8e-46 158.0 0.0 2.2e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKO97500.1 - 1.9e-13 49.8 0.1 6.2e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribosomal_L12 PF00542.19 RKO97501.1 - 1.7e-20 73.1 6.8 1.7e-20 73.1 6.8 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 RKO97501.1 - 2.9e-08 33.3 23.2 2.9e-08 33.3 23.2 4.0 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 RKO97501.1 - 0.00027 21.4 12.5 0.00027 21.4 12.5 2.4 1 1 1 2 2 2 1 60s Acidic ribosomal protein Bac_DNA_binding PF00216.21 RKO97501.1 - 0.025 14.8 0.8 0.025 14.8 0.8 1.8 2 0 0 2 2 2 0 Bacterial DNA-binding protein Cas_Csy2 PF09614.10 RKO97501.1 - 0.041 13.3 0.1 0.066 12.6 0.1 1.4 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) MelC1 PF06236.11 RKO97501.1 - 0.15 12.1 4.1 0.27 11.3 4.1 1.4 1 0 0 1 1 1 0 Tyrosinase co-factor MelC1 ASH PF15780.5 RKO97502.1 - 2.8e-23 82.0 18.9 0.0033 17.6 0.1 14.4 15 2 1 17 17 16 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 RKO97502.1 - 9.2e-14 51.3 0.0 0.55 10.3 0.0 10.6 13 0 0 13 13 13 4 Protein of unknown function (DUF1573) PapD-like PF14874.6 RKO97502.1 - 1.4e-13 50.8 1.3 0.41 10.8 0.0 8.2 9 0 0 9 9 9 3 Flagellar-associated PapD-like Motile_Sperm PF00635.26 RKO97502.1 - 8.4e-08 32.0 0.3 2.3 8.1 0.0 8.4 9 0 0 9 9 9 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 RKO97502.1 - 6.7e-07 29.5 11.8 0.11 12.7 0.0 8.0 11 0 0 11 11 10 3 Transmembrane protein 131-like MYCBPAP PF14646.6 RKO97502.1 - 6.4e-06 25.4 0.2 2.3 7.0 0.0 5.1 6 0 0 6 6 6 2 MYCBP-associated protein family Ig_GlcNase PF18368.1 RKO97502.1 - 0.00017 21.7 0.3 12 6.2 0.0 5.7 5 0 0 5 5 5 1 Exo-beta-D-glucosaminidase Ig-fold domain AAA_33 PF13671.6 RKO97502.1 - 0.0026 17.9 0.0 0.0077 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF5001 PF16392.5 RKO97502.1 - 0.0036 17.2 1.6 14 5.6 0.0 5.5 5 1 2 7 7 7 1 Ig-like domain AAA_18 PF13238.6 RKO97502.1 - 0.01 16.4 0.0 0.021 15.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain fn3_5 PF06280.12 RKO97502.1 - 0.083 13.6 5.7 26 5.5 0.1 6.2 7 0 0 7 7 7 0 Fn3-like domain CPT PF07931.12 RKO97502.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.23 RKO97503.1 - 8.1e-15 54.9 0.5 2.7e-14 53.2 0.2 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 RKO97503.1 - 7.9e-06 25.5 0.2 1.5e-05 24.5 0.1 1.5 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 RKO97503.1 - 5.3e-05 23.2 0.0 0.0006 19.8 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AIG1 PF04548.16 RKO97503.1 - 0.011 15.1 0.1 0.035 13.4 0.1 1.8 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.27 RKO97503.1 - 0.059 12.9 0.2 0.26 10.8 0.1 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 RKO97503.1 - 0.074 13.1 0.6 4.7 7.2 0.1 2.6 2 1 0 3 3 3 0 Dynamin family AAA_18 PF13238.6 RKO97503.1 - 0.085 13.4 0.5 0.15 12.6 0.5 1.4 1 0 0 1 1 1 0 AAA domain IIGP PF05049.13 RKO97503.1 - 0.2 10.6 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Exo84_C PF16528.5 RKO97504.1 - 1.2e-19 71.0 9.6 7.8e-15 55.2 0.0 4.2 4 0 0 4 4 4 3 Exocyst component 84 C-terminal UIM PF02809.20 RKO97504.1 - 0.04 13.9 10.7 0.97 9.5 2.3 2.8 2 0 0 2 2 2 0 Ubiquitin interaction motif GREB1 PF15782.5 RKO97504.1 - 1.2 6.1 11.7 1.7 5.6 11.7 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Cyclin_N PF00134.23 RKO97505.1 - 8e-34 116.1 0.2 3.7e-32 110.8 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 RKO97505.1 - 3.1e-17 62.8 0.1 5.4e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 RKO97505.1 - 0.0069 16.8 0.1 0.011 16.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin C-terminal domain Pkinase PF00069.25 RKO97506.1 - 7.9e-36 123.8 0.0 3.4e-32 111.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97506.1 - 1.1e-13 51.1 0.0 2.6e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97506.1 - 0.00049 19.5 0.0 0.00085 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 RKO97506.1 - 0.0066 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ER_lumen_recept PF00810.18 RKO97508.1 - 8.7e-50 169.4 4.8 1.2e-49 168.9 4.8 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 RKO97508.1 - 3.4 7.5 6.9 0.88 9.4 0.2 3.2 4 0 0 4 4 4 0 PQ loop repeat WD40 PF00400.32 RKO97509.1 - 0.01 16.6 0.3 1.9 9.5 0.1 3.0 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_3 PF13570.6 RKO97509.1 - 0.26 11.8 0.1 0.26 11.8 0.1 3.8 4 0 0 4 4 4 0 PQQ-like domain Ribosomal_L6 PF00347.23 RKO97510.1 - 2.4e-28 98.6 0.9 8.7e-14 52.0 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 DLH PF01738.18 RKO97511.1 - 1.8e-13 50.5 0.0 2.5e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Prim-Pol PF09250.11 RKO97512.1 - 2.6e-14 53.9 0.0 4.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Bifunctional DNA primase/polymerase, N-terminal D5_N PF08706.11 RKO97512.1 - 6.8e-06 26.4 0.0 1.5e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 D5 N terminal like AAA_18 PF13238.6 RKO97512.1 - 0.16 12.5 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-C2H2_4 PF13894.6 RKO97513.1 - 0.006 17.3 0.1 0.32 11.9 0.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 RKO97513.1 - 0.0068 16.8 0.1 0.41 11.2 0.0 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-Di19 PF05605.12 RKO97513.1 - 0.62 10.4 1.9 8.1 6.8 0.1 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Pkinase PF00069.25 RKO97515.1 - 1.1e-24 87.3 0.0 1.3e-24 87.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97515.1 - 8.5e-13 48.2 0.0 1.1e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO97515.1 - 3.8e-11 42.4 0.0 4.9e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKO97515.1 - 0.00018 21.5 0.0 0.0017 18.3 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 RKO97515.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 RKO97515.1 - 0.029 13.7 0.1 0.06 12.7 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 RKO97515.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Sod_Cu PF00080.20 RKO97517.1 - 2.6e-50 170.3 6.6 3e-50 170.1 6.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) BppL_N PF18338.1 RKO97517.1 - 0.016 15.0 0.9 0.21 11.4 0.1 3.0 3 0 0 3 3 3 0 Lower baseplate protein N-terminal domain Big_3_5 PF16640.5 RKO97517.1 - 0.78 10.0 6.6 2.1 8.6 3.1 2.6 2 1 0 2 2 2 0 Bacterial Ig-like domain (group 3) Foie-gras_1 PF11817.8 RKO97518.1 - 0.01 15.4 0.0 0.036 13.6 0.0 1.9 1 0 0 1 1 1 0 Foie gras liver health family 1 TPR_7 PF13176.6 RKO97518.1 - 0.023 14.7 0.0 0.13 12.3 0.0 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 RKO97518.1 - 0.042 14.7 0.0 0.042 14.7 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.14 RKO97518.1 - 0.059 14.0 0.0 0.059 14.0 0.0 5.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKO97518.1 - 0.065 13.4 0.0 0.32 11.2 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DIOX_N PF14226.6 RKO97519.1 - 7.3e-28 97.7 0.0 1.1e-27 97.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 RKO97519.1 - 6.1e-19 68.4 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-synt_ab PF00006.25 RKO97521.1 - 1.3e-71 240.6 0.0 2e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 RKO97521.1 - 5.4e-46 156.0 0.1 9.7e-46 155.2 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 RKO97521.1 - 1.4e-19 70.3 2.7 5.3e-19 68.5 2.7 2.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase_2 PF01637.18 RKO97521.1 - 0.052 13.5 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea HAS-barrel PF09378.10 RKO97521.1 - 0.092 12.9 2.7 1.5 9.0 0.1 2.7 1 1 1 2 2 2 0 HAS barrel domain Ribosomal_L21p PF00829.21 RKO97522.1 - 4.7e-15 55.7 0.1 5.5e-15 55.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein RRM_1 PF00076.22 RKO97523.1 - 8.3e-09 35.2 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 RKO97523.1 - 8.4e-05 23.3 0.0 0.00015 22.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_7 PF16367.5 RKO97523.1 - 0.045 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif M11L PF11099.8 RKO97523.1 - 0.16 12.2 0.3 0.28 11.4 0.2 1.4 1 1 0 1 1 1 0 Apoptosis regulator M11L like DUF1631 PF07793.11 RKO97523.1 - 0.31 9.4 10.2 0.52 8.7 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) DEP PF00610.21 RKO97524.1 - 1e-05 25.5 0.0 2.4e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 RKO97524.1 - 9.6e-05 22.6 0.0 0.00036 20.8 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain tRNA-synt_1 PF00133.22 RKO97525.1 - 2.7e-33 115.1 0.1 3.3e-21 75.2 0.0 3.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 RKO97525.1 - 2.3e-18 66.1 0.0 1.6e-07 30.4 0.0 3.1 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 RKO97525.1 - 6.6e-12 45.6 0.0 1.3e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 RKO97525.1 - 1.1e-10 41.4 0.0 2.3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 RKO97525.1 - 0.015 14.2 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) DUF413 PF04219.12 RKO97525.1 - 0.033 14.2 0.0 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF GATase_2 PF00310.21 RKO97526.1 - 1.5e-171 570.7 0.0 2.1e-171 570.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 RKO97526.1 - 2.3e-152 507.4 0.0 4.9e-151 503.0 0.0 2.6 3 0 0 3 3 3 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 RKO97526.1 - 2.2e-108 362.0 0.0 7.8e-108 360.2 0.0 1.8 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 RKO97526.1 - 9.9e-84 279.7 0.0 1.8e-83 278.8 0.0 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 RKO97526.1 - 3.6e-20 71.8 0.1 6.3e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 RKO97526.1 - 2.4e-16 59.8 0.2 4.3e-16 59.0 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 RKO97526.1 - 6.2e-08 32.8 0.0 2.4e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 RKO97526.1 - 4.2e-06 27.2 0.6 0.0067 17.0 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 RKO97526.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 RKO97526.1 - 0.00014 20.7 0.1 0.00014 20.7 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 RKO97526.1 - 0.00019 21.1 0.7 0.012 15.2 0.1 2.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 RKO97526.1 - 0.00023 21.2 0.1 0.031 14.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 RKO97526.1 - 0.0003 20.3 0.9 0.00063 19.2 0.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 RKO97526.1 - 0.00042 19.7 0.1 0.00076 18.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 RKO97526.1 - 0.00056 19.1 0.3 0.00099 18.3 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 RKO97526.1 - 0.00069 20.0 2.4 0.18 12.2 0.2 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 RKO97526.1 - 0.00078 18.8 1.0 0.086 12.1 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 RKO97526.1 - 0.00084 18.7 0.4 0.057 12.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 RKO97526.1 - 0.0016 17.9 0.0 0.034 13.5 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 RKO97526.1 - 0.044 13.8 0.8 3.8 7.6 0.1 2.9 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Thi4 PF01946.17 RKO97526.1 - 0.051 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 RKO97526.1 - 0.093 12.7 0.1 0.43 10.6 0.0 2.3 1 1 1 2 2 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 RKO97526.1 - 0.096 12.6 0.3 0.22 11.4 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 RKO97526.1 - 0.1 12.2 0.1 0.24 11.1 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pirin PF02678.16 RKO97526.1 - 0.16 12.0 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 Pirin GIDA PF01134.22 RKO97526.1 - 1.5 7.8 6.0 0.16 11.0 0.7 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A RasGEF PF00617.19 RKO97528.1 - 1e-29 104.0 0.0 3.2e-20 73.1 0.0 2.2 2 0 0 2 2 2 2 RasGEF domain RasGEF_N PF00618.20 RKO97528.1 - 1e-08 35.3 0.0 5.3e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 RasGEF N-terminal motif Adaptin_N PF01602.20 RKO97530.1 - 5.4e-89 299.1 0.0 6.3e-88 295.6 0.0 2.0 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 RKO97530.1 - 4.9e-17 62.4 0.7 5.1e-16 59.1 0.8 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 RKO97530.1 - 7.9e-05 23.0 19.1 0.00022 21.6 0.2 6.3 5 1 0 5 5 5 1 HEAT repeats TFIIA PF03153.13 RKO97530.1 - 0.025 14.6 0.3 0.025 14.6 0.3 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HEAT PF02985.22 RKO97530.1 - 6 7.4 10.0 9.8 6.7 0.1 5.5 6 0 0 6 6 6 0 HEAT repeat Methyltransf_12 PF08242.12 RKO97531.1 - 0.0089 16.8 0.0 0.011 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO97531.1 - 0.048 14.4 0.0 0.062 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 RKO97531.1 - 0.064 13.1 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain SAICAR_synt PF01259.18 RKO97532.1 - 3.1e-97 325.1 0.0 3.7e-97 324.9 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Spec3 PF15795.5 RKO97532.1 - 0.028 14.9 0.0 0.059 13.9 0.0 1.5 1 0 0 1 1 1 0 Ectodermal ciliogenesis protein DUF1192 PF06698.11 RKO97532.1 - 0.046 13.8 1.3 0.086 12.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) UQ_con PF00179.26 RKO97533.1 - 1.3e-29 102.6 0.0 1.4e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GalP_UDP_transf PF01087.22 RKO97534.1 - 9e-55 185.9 0.0 1.4e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 RKO97534.1 - 5.1e-44 149.9 0.0 9.6e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 RKO97534.1 - 3.6e-06 27.6 0.0 0.00035 21.2 0.0 2.6 2 1 0 2 2 2 1 HIT domain DUF4921 PF16268.5 RKO97534.1 - 0.13 11.0 0.4 2.5 6.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) SH3_1 PF00018.28 RKO97535.1 - 7.8e-13 47.8 0.0 8.9e-13 47.6 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 RKO97535.1 - 1.3e-10 40.9 0.0 1.5e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKO97535.1 - 3.9e-09 36.1 0.0 3.9e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_4 PF06347.13 RKO97535.1 - 0.049 13.5 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 Bacterial SH3 domain Serglycin PF04360.12 RKO97536.1 - 0.047 13.6 2.6 0.19 11.7 2.6 1.8 1 1 0 1 1 1 0 Serglycin DUF515 PF04415.12 RKO97536.1 - 0.066 11.6 0.2 0.081 11.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Serglycin PF04360.12 RKO97537.1 - 0.0077 16.2 4.9 0.0077 16.2 4.9 4.8 4 1 0 4 4 4 2 Serglycin DEAD PF00270.29 RKO97541.1 - 1.5e-26 93.2 0.1 5e-24 85.0 0.1 3.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO97541.1 - 1.2e-25 90.0 0.0 2.4e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO97541.1 - 0.0033 17.4 0.0 0.01 15.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_membrane_2 PF06472.15 RKO97543.1 - 1.8e-93 312.9 2.9 2.8e-93 312.2 2.9 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 RKO97543.1 - 2.1e-14 54.2 0.0 6.8e-14 52.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 RKO97543.1 - 8.4e-05 22.5 0.0 0.0002 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RKO97543.1 - 0.0084 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 RKO97543.1 - 0.025 15.1 0.2 0.086 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 RKO97543.1 - 0.039 13.4 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_27 PF13514.6 RKO97543.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF498 PF04430.14 RKO97544.1 - 1.7e-28 98.8 0.0 1.9e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) AAA PF00004.29 RKO97544.1 - 0.18 12.2 0.0 0.22 11.9 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dUTPase PF00692.19 RKO97545.1 - 1.5e-38 131.4 0.0 1.7e-38 131.3 0.0 1.0 1 0 0 1 1 1 1 dUTPase CoaE PF01121.20 RKO97546.1 - 9.5e-51 172.0 0.1 1.3e-50 171.6 0.1 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 RKO97546.1 - 0.0002 21.9 0.0 0.0011 19.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKO97546.1 - 0.0023 18.1 0.1 0.017 15.3 0.1 2.7 1 1 0 1 1 1 1 AAA domain HTH_ABP1_N PF18107.1 RKO97546.1 - 0.005 16.5 0.0 0.017 14.9 0.0 1.8 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain TetR_C_32 PF09209.11 RKO97546.1 - 0.0097 15.9 0.7 0.018 15.1 0.7 1.5 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain SKI PF01202.22 RKO97546.1 - 0.058 13.5 0.3 5.6 7.1 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase LacI PF00356.21 RKO97546.1 - 0.086 12.7 0.3 9.1 6.2 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family dNK PF01712.19 RKO97546.1 - 0.11 12.3 0.1 3.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_28 PF13521.6 RKO97546.1 - 0.16 12.2 1.1 2.1 8.6 1.1 2.5 1 1 0 1 1 1 0 AAA domain XendoU PF09412.10 RKO97547.1 - 1.7e-72 243.8 0.0 2.5e-72 243.3 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease XendoU AWPM-19 PF05512.11 RKO97547.1 - 0.51 10.5 1.6 0.94 9.7 1.6 1.4 1 0 0 1 1 1 0 AWPM-19-like family Hydrophobin PF01185.18 RKO97550.1 - 0.0045 17.6 10.6 0.0069 17.0 10.6 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Acyl-CoA_dh_M PF02770.19 RKO97551.1 - 1.9e-27 95.3 0.1 3.3e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 RKO97551.1 - 3.9e-26 91.9 0.0 6e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.8 RKO97551.1 - 3.4e-05 23.6 0.1 0.00013 21.7 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal SWIB PF02201.18 RKO97553.1 - 1.7e-18 66.2 0.0 3.3e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF1116 PF06545.11 RKO97553.1 - 0.14 11.6 0.2 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Snf7 PF03357.21 RKO97554.1 - 6.2e-32 110.6 8.7 8.1e-32 110.2 8.7 1.2 1 0 0 1 1 1 1 Snf7 Pox_G7 PF05503.12 RKO97554.1 - 0.034 13.1 0.2 0.043 12.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus G7-like DUF3585 PF12130.8 RKO97554.1 - 0.2 11.8 5.2 0.32 11.1 5.2 1.5 1 1 0 1 1 1 0 Bivalent Mical/EHBP Rab binding domain CheX PF13690.6 RKO97554.1 - 0.96 9.7 3.7 34 4.7 3.7 2.3 1 1 0 1 1 1 0 Chemotaxis phosphatase CheX Hydrophobin PF01185.18 RKO97555.1 - 6.6e-11 42.7 9.9 8.3e-11 42.4 9.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Ecm33 PF12454.8 RKO97555.1 - 1.7 8.8 7.4 2.8 8.1 0.6 2.4 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Vac14_Fab1_bd PF12755.7 RKO97556.1 - 5.3e-11 43.0 0.3 4.2e-05 24.1 0.1 3.8 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 RKO97556.1 - 6.9e-07 29.6 19.1 0.053 14.0 0.0 7.0 7 0 0 7 7 6 2 HEAT-like repeat HEAT PF02985.22 RKO97556.1 - 1.4e-05 24.9 9.2 0.57 10.6 0.0 6.0 7 0 0 7 7 7 3 HEAT repeat ParcG PF10274.9 RKO97556.1 - 0.00014 22.0 0.5 0.24 11.5 0.1 3.2 3 1 1 4 4 4 2 Parkin co-regulated protein CLASP_N PF12348.8 RKO97556.1 - 0.00043 19.9 2.6 0.05 13.2 0.4 2.6 2 1 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 RKO97556.1 - 0.00099 19.2 0.2 0.074 13.1 0.1 3.2 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 RKO97556.1 - 0.015 13.8 8.0 0.82 8.2 0.8 3.3 3 1 0 4 4 4 0 Adaptin N terminal region HEAT_2 PF13646.6 RKO97556.1 - 0.016 15.6 23.8 0.2 12.1 0.7 6.0 5 2 2 7 7 7 0 HEAT repeats DRIM PF07539.12 RKO97556.1 - 0.023 13.0 1.7 0.098 10.9 0.3 2.4 2 1 0 2 2 2 0 Down-regulated in metastasis IFRD PF05004.13 RKO97556.1 - 0.033 13.3 1.1 6.6 5.7 0.0 3.3 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 RKO97556.1 - 0.038 13.9 0.1 8.1 6.3 0.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) Arm PF00514.23 RKO97556.1 - 0.19 11.8 10.3 3.4 7.8 0.2 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat RTC4 PF14474.6 RKO97557.1 - 1.3e-13 51.2 0.0 3e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain FYDLN_acid PF09538.10 RKO97557.1 - 0.0052 17.4 4.5 0.006 17.3 1.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) zf-WRNIP1_ubi PF18279.1 RKO97557.1 - 0.066 13.9 0.3 0.17 12.6 0.3 1.7 1 0 0 1 1 1 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF3391 PF11871.8 RKO97557.1 - 4.7 7.7 7.0 0.96 10.0 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) ubiquitin PF00240.23 RKO97559.1 - 2.1e-137 447.1 35.0 1.2e-33 114.6 0.9 5.9 5 1 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 RKO97559.1 - 2.7e-59 196.9 30.2 2.5e-15 56.0 1.0 5.8 5 1 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 RKO97559.1 - 1.2e-22 80.2 16.8 0.00021 21.7 0.2 7.2 5 4 1 6 6 6 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 RKO97559.1 - 4.6e-12 46.0 6.9 0.07 13.2 0.0 6.2 5 4 1 6 6 6 3 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 RKO97559.1 - 6.8e-12 45.2 7.3 0.022 14.7 0.1 4.5 5 0 0 5 5 4 3 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 RKO97559.1 - 2.6e-11 43.7 11.3 0.031 14.6 0.1 4.4 3 1 1 4 4 4 3 Ubiquitin-like domain DUF2407 PF10302.9 RKO97559.1 - 8e-11 42.4 5.0 0.032 14.8 0.2 3.9 2 2 2 4 4 4 3 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 RKO97559.1 - 1.8e-07 31.1 28.6 7.9 6.6 0.3 8.8 8 1 1 9 9 9 0 Ubiquitin-like domain DUF3861 PF12977.7 RKO97559.1 - 6.9e-07 29.4 5.3 9 6.5 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) Methyltrans_RNA PF04452.14 RKO97559.1 - 7.1e-07 28.8 1.9 3.5 6.9 0.0 4.1 4 0 0 4 4 4 3 RNA methyltransferase DUF493 PF04359.14 RKO97559.1 - 8.3e-07 29.5 0.3 45 4.7 0.0 5.1 5 0 0 5 5 5 0 Protein of unknown function (DUF493) UDP-g_GGTase PF06427.11 RKO97559.1 - 1.8e-06 28.0 5.4 5.8 7.1 0.0 4.7 4 1 1 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase TmoB PF06234.12 RKO97559.1 - 2e-06 27.8 0.9 41 4.4 0.0 5.6 5 0 0 5 5 5 0 Toluene-4-monooxygenase system protein B (TmoB) Big_7 PF17957.1 RKO97559.1 - 3.1e-06 27.8 0.5 63 4.4 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain Big_3_3 PF13750.6 RKO97559.1 - 1.2e-05 25.0 0.5 38 3.9 0.0 5.0 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) ACT_5 PF13710.6 RKO97559.1 - 3.6e-05 23.5 9.9 18 5.2 0.1 5.3 5 0 0 5 5 5 0 ACT domain DUF2870 PF11069.8 RKO97559.1 - 0.00013 22.3 0.0 37 4.8 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) Baculo_p48 PF04878.13 RKO97559.1 - 0.00023 20.2 0.0 15 4.3 0.0 4.1 4 0 0 4 4 4 0 Baculovirus P48 protein ACT_4 PF13291.6 RKO97559.1 - 0.00028 21.4 4.2 76 4.0 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF1940 PF09155.10 RKO97559.1 - 0.00031 20.9 8.0 18 5.4 0.0 5.0 4 1 0 5 5 5 0 Domain of unknown function (DUF1940) ORF11CD3 PF10549.9 RKO97559.1 - 0.00065 19.8 0.0 1.1e+02 3.1 0.0 5.2 4 0 0 4 4 4 0 ORF11CD3 domain DUF969 PF06149.12 RKO97559.1 - 0.0025 17.3 0.1 26 4.1 0.0 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF969) Raf1_HTH PF18579.1 RKO97559.1 - 0.011 15.4 2.3 46 3.8 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain ProRS-C_2 PF09181.10 RKO97559.1 - 0.031 14.4 10.6 72 3.6 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal FERM_f0 PF16511.5 RKO97559.1 - 0.057 13.7 8.1 40 4.6 0.0 5.9 5 3 0 5 5 5 0 N-terminal or F0 domain of Talin-head FERM CC2-LZ PF16516.5 RKO97559.1 - 0.11 12.8 2.1 12 6.4 0.0 4.3 5 0 0 5 5 5 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Tash_PEST PF07708.11 RKO97559.1 - 0.14 12.4 36.0 7.5 6.9 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif PI3K_p85B PF02192.16 RKO97559.1 - 0.15 11.8 15.7 43 4.0 0.1 5.2 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Myosin_N PF02736.19 RKO97559.1 - 0.3 11.0 9.4 1.3e+02 2.5 0.0 5.8 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain Coagulin PF02035.15 RKO97559.1 - 1.7 8.5 8.1 22 4.9 0.1 4.6 5 0 0 5 5 5 0 Coagulin HAMP_N3 PF18575.1 RKO97559.1 - 2.7 7.6 6.2 2.8e+02 1.2 0.0 4.6 5 0 0 5 5 5 0 HAMP N-terminal domain 3 Plexin_cytopl PF08337.12 RKO97559.1 - 5 5.7 26.5 8.6 4.9 0.9 5.7 4 3 1 5 5 5 0 Plexin cytoplasmic RasGAP domain GDI PF00996.18 RKO97560.1 - 6.2e-218 723.6 0.0 7.5e-218 723.3 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Acyl-CoA_dh_1 PF00441.24 RKO97561.1 - 6.3e-09 36.2 0.1 7.1e-09 36.0 0.1 1.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MMS1_N PF10433.9 RKO97563.1 - 5.5e-60 203.4 0.0 1.3e-59 202.2 0.0 1.6 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RKO97563.1 - 1.4e-36 126.5 0.0 2.4e-27 96.1 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region NOA36 PF06524.12 RKO97563.1 - 6.6 5.9 4.7 14 4.9 4.7 1.4 1 0 0 1 1 1 0 NOA36 protein Pro_isomerase PF00160.21 RKO97565.1 - 8.1e-46 156.2 0.3 1e-45 155.9 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Synaptobrevin PF00957.21 RKO97566.1 - 5.5e-22 77.4 0.3 5.9e-22 77.3 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin TTL PF03133.15 RKO97566.1 - 0.013 14.6 0.0 0.016 14.4 0.0 1.0 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family Herpes_teg_N PF04843.12 RKO97566.1 - 0.066 12.9 0.0 0.067 12.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus tegument protein, N-terminal conserved region RRP36 PF06102.12 RKO97567.1 - 1.9 8.5 4.1 0.68 9.9 0.3 2.1 2 1 0 2 2 2 0 rRNA biogenesis protein RRP36 AAA_6 PF12774.7 RKO97568.1 - 4.4e-157 522.2 0.1 3e-156 519.4 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKO97568.1 - 3e-122 408.5 2.3 3e-122 408.5 2.3 3.8 3 1 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 RKO97568.1 - 2.6e-95 318.6 0.0 6.4e-95 317.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKO97568.1 - 1.5e-81 272.7 0.2 1.5e-81 272.7 0.2 3.1 4 0 0 4 4 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 RKO97568.1 - 1.7e-77 260.7 1.6 6.3e-77 258.8 0.0 2.8 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 RKO97568.1 - 3.5e-74 248.3 1.7 4.9e-68 228.2 0.0 3.9 4 0 0 4 4 3 2 P-loop containing dynein motor region MT PF12777.7 RKO97568.1 - 2.9e-53 181.1 16.0 8.7e-52 176.2 11.5 2.6 2 1 0 2 2 2 2 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 RKO97568.1 - 1.9e-47 161.2 0.0 4.3e-47 160.0 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKO97568.1 - 7.8e-44 148.6 0.0 2.3e-42 143.9 0.0 3.4 3 0 0 3 3 3 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 RKO97568.1 - 4.8e-26 91.4 0.0 3.8e-07 30.2 0.0 4.8 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKO97568.1 - 1.2e-19 70.7 0.0 8.8e-19 67.9 0.0 2.6 3 0 0 3 3 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 RKO97568.1 - 3.5e-15 56.0 0.1 1.2e-14 54.3 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 RKO97568.1 - 2.5e-08 34.4 0.0 0.55 10.7 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 RKO97568.1 - 4.5e-07 30.2 9.0 0.028 14.7 0.0 5.5 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.6 RKO97568.1 - 1.2e-06 29.1 0.1 0.021 15.3 0.0 5.0 4 0 0 4 4 4 1 AAA domain Apolipoprotein PF01442.18 RKO97568.1 - 6e-05 23.0 1.1 6e-05 23.0 1.1 5.3 4 1 1 5 5 4 2 Apolipoprotein A1/A4/E domain AAA_30 PF13604.6 RKO97568.1 - 0.00024 20.9 1.2 0.74 9.5 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 RKO97568.1 - 0.00036 21.0 11.4 0.23 11.8 0.0 6.5 6 1 1 7 7 5 1 AAA ATPase domain AAA_29 PF13555.6 RKO97568.1 - 0.0011 18.7 0.1 0.21 11.4 0.0 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 RKO97568.1 - 0.029 14.8 1.2 3.3 8.1 0.0 3.3 3 0 0 3 3 2 0 RNA helicase RsgA_GTPase PF03193.16 RKO97568.1 - 0.052 13.4 0.1 0.41 10.5 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Rad17 PF03215.15 RKO97568.1 - 0.1 12.5 0.2 21 5.0 0.0 2.9 2 0 0 2 2 2 0 Rad17 P-loop domain Sigma54_activat PF00158.26 RKO97568.1 - 0.13 12.0 0.0 1.4 8.6 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_33 PF13671.6 RKO97568.1 - 0.24 11.6 1.0 33 4.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 RKO97568.1 - 0.57 10.5 3.9 1.4e+02 2.8 0.3 4.5 5 0 0 5 5 3 0 AAA domain F-box-like PF12937.7 RKO97569.1 - 3.7e-07 29.9 5.3 5.9e-07 29.3 1.4 3.2 3 0 0 3 3 3 1 F-box-like Spt20 PF12090.8 RKO97569.1 - 0.078 12.6 7.8 0.37 10.3 7.0 2.0 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 RKO97569.1 - 3.7 7.4 11.7 0.52 10.3 7.3 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_tranf_2_3 PF13641.6 RKO97571.1 - 0.0025 17.8 0.1 0.0075 16.2 0.0 1.7 1 1 1 2 2 2 1 Glycosyltransferase like family 2 TPR_2 PF07719.17 RKO97572.1 - 0.0053 16.8 0.1 11 6.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 RKO97572.1 - 0.023 14.5 0.0 58 3.7 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat 3-HAO PF06052.12 RKO97573.1 - 5.9e-65 217.5 0.0 7e-65 217.3 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Nudix_N_2 PF14803.6 RKO97573.1 - 0.002 18.0 1.9 0.98 9.4 0.1 2.5 2 0 0 2 2 2 2 Nudix N-terminal Cupin_2 PF07883.11 RKO97573.1 - 0.003 17.3 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain DZR PF12773.7 RKO97573.1 - 0.0038 17.2 1.2 0.0072 16.3 1.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon Zn-ribbon_8 PF09723.10 RKO97573.1 - 0.01 15.9 0.6 0.04 14.0 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 RKO97573.1 - 0.034 14.1 1.8 7.9 6.6 0.1 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RanBP PF00641.18 RKO97573.1 - 0.035 13.4 3.3 0.63 9.4 0.1 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-ribbon_3 PF13248.6 RKO97573.1 - 0.095 12.1 2.8 5.9 6.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_17 PF17120.5 RKO97573.1 - 0.27 10.9 3.3 0.24 11.0 0.9 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RRP7 PF12923.7 RKO97574.1 - 9.9e-17 61.2 0.0 2.1e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Neisseria_TspB PF05616.13 RKO97575.1 - 0.26 9.7 5.5 0.43 9.0 5.5 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Ydr279_N PF17745.1 RKO97576.1 - 8.5e-11 42.0 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 RKO97576.1 - 0.00059 20.1 0.0 0.00086 19.5 0.0 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain V-SNARE_C PF12352.8 RKO97577.1 - 6.7e-14 51.9 1.6 1.2e-13 51.1 1.0 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RKO97577.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.4 1 0 0 1 1 1 1 Sec20 DUF3450 PF11932.8 RKO97577.1 - 0.017 14.5 3.6 0.031 13.6 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4337 PF14235.6 RKO97577.1 - 0.042 14.0 1.9 1.4 9.1 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) HALZ PF02183.18 RKO97577.1 - 0.075 13.3 1.4 0.14 12.4 0.3 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper SKA2 PF16740.5 RKO97577.1 - 0.12 12.2 4.2 0.3 10.9 2.2 2.4 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 YkyA PF10368.9 RKO97577.1 - 0.14 11.9 2.6 0.11 12.2 0.5 1.8 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein DUF4407 PF14362.6 RKO97577.1 - 0.15 11.4 8.1 0.62 9.4 8.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MDMPI_N PF11716.8 RKO97577.1 - 2.2 9.0 10.1 2.2 8.9 4.6 2.2 1 1 1 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain Vps55 PF04133.14 RKO97579.1 - 8.8e-38 128.9 6.4 1e-37 128.7 6.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Herpes_LMP1 PF05297.11 RKO97579.1 - 0.36 10.0 3.2 0.63 9.2 3.2 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) p450 PF00067.22 RKO97581.1 - 1.1e-71 242.1 0.0 1.6e-71 241.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Nup84_Nup100 PF04121.13 RKO97581.1 - 0.3 9.1 0.0 0.41 8.7 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 Sda PF08970.10 RKO97582.1 - 0.01 15.5 9.3 2.1 8.2 0.0 5.2 6 0 0 6 6 6 0 Sporulation inhibitor A SpoIIIAH PF12685.7 RKO97582.1 - 3.9 7.3 10.3 0.37 10.6 3.3 2.6 2 0 0 2 2 2 0 SpoIIIAH-like protein RGS PF00615.19 RKO97583.1 - 0.019 15.3 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signaling domain SMC_N PF02463.19 RKO97584.1 - 3.2e-36 124.8 0.1 5.5e-36 124.1 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 RKO97584.1 - 6.7e-17 62.6 11.4 1.8e-16 61.2 11.4 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 RKO97584.1 - 1.1e-09 38.5 4.3 7.2e-09 35.8 4.3 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 RKO97584.1 - 2.8e-06 27.4 0.4 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 RKO97584.1 - 0.0035 17.1 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 RKO97584.1 - 0.0054 16.9 3.2 0.33 11.0 0.0 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain Ribosomal_L36e PF01158.18 RKO97584.1 - 0.017 15.3 1.3 0.046 14.0 1.3 1.8 1 0 0 1 1 1 0 Ribosomal protein L36e XH PF03469.14 RKO97584.1 - 0.022 14.6 2.1 0.17 11.8 0.5 2.1 1 1 1 2 2 2 0 XH domain FtsK_SpoIIIE PF01580.18 RKO97584.1 - 0.064 12.6 0.3 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_13 PF13166.6 RKO97584.1 - 0.088 11.4 0.0 0.088 11.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RKO97584.1 - 0.15 12.6 4.3 3.1 8.3 4.3 2.3 1 1 0 1 1 1 0 ABC transporter Atg14 PF10186.9 RKO97584.1 - 0.81 8.7 11.6 1.1 8.3 11.6 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rad9 PF04139.13 RKO97585.1 - 7e-37 127.2 0.0 1.4e-28 100.0 0.0 2.8 2 1 0 2 2 2 2 Rad9 OGG_N PF07934.12 RKO97586.1 - 3.9e-22 78.6 0.0 6.2e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 RKO97586.1 - 2.6e-11 43.9 0.0 4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 RKO97586.1 - 0.00028 20.6 0.0 0.00061 19.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif T6SS_TssG PF06996.11 RKO97586.1 - 0.041 13.1 0.1 4.5 6.4 0.0 2.7 2 1 1 3 3 3 0 Type VI secretion, TssG F-box-like PF12937.7 RKO97587.1 - 0.017 15.0 0.4 0.017 15.0 0.4 2.2 2 0 0 2 2 2 0 F-box-like Peptidase_M16 PF00675.20 RKO97588.1 - 1.5e-26 93.2 0.1 2.1e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 RKO97588.1 - 3.3e-06 27.2 0.0 7.7e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Spb1_C PF07780.12 RKO97589.1 - 3.5e-61 206.5 12.6 3.5e-61 206.5 12.6 2.8 2 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 RKO97589.1 - 2.9e-54 183.9 0.0 5.3e-54 183.0 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 RKO97589.1 - 1.2e-34 119.5 0.4 1.2e-34 119.5 0.4 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 RKO97589.1 - 0.065 13.1 0.0 0.32 10.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain EF1_GNE PF00736.19 RKO97590.1 - 6.5e-34 116.0 1.2 6.5e-34 116.0 1.2 1.9 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 RKO97590.1 - 1.6e-15 57.2 4.8 1.6e-15 57.2 4.8 2.6 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Cwf_Cwc_15 PF04889.12 RKO97590.1 - 0.00074 19.3 1.2 0.001 18.9 1.2 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GST_C_3 PF14497.6 RKO97590.1 - 0.01 16.0 0.2 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 RKO97590.1 - 0.015 15.1 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF3752 PF12572.8 RKO97590.1 - 0.034 14.7 2.2 0.054 14.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) NOP5NT PF08156.13 RKO97590.1 - 0.076 13.4 0.1 0.37 11.2 0.1 2.2 1 1 0 1 1 1 0 NOP5NT (NUC127) domain YL1 PF05764.13 RKO97590.1 - 0.17 11.9 6.6 0.22 11.6 6.6 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DNA_pol_phi PF04931.13 RKO97591.1 - 0.1 10.7 6.6 0.13 10.3 6.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rhabdo_ncap PF00945.18 RKO97591.1 - 0.17 10.8 1.1 0.23 10.3 1.1 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein FYDLN_acid PF09538.10 RKO97591.1 - 0.49 11.1 11.0 0.38 11.4 6.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) FAM176 PF14851.6 RKO97591.1 - 1.1 8.9 5.4 0.43 10.2 0.7 2.0 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 RKO97591.1 - 2.6 8.0 6.4 0.69 9.9 2.8 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4200 PF13863.6 RKO97592.1 - 3.4e-26 92.0 17.4 3.4e-26 92.0 17.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) JIP_LZII PF16471.5 RKO97592.1 - 0.024 14.8 1.9 0.024 14.8 1.9 2.6 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Phosphodiest PF01663.22 RKO97592.1 - 0.29 10.7 0.8 0.5 9.9 0.1 1.5 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase UPF0242 PF06785.11 RKO97592.1 - 0.83 9.7 22.0 1.2 9.2 1.7 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 RKO97592.1 - 1.2 9.2 9.2 6.3 6.9 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4464 PF14713.6 RKO97592.1 - 5.2 6.6 8.9 0.13 11.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4464) COG2 PF06148.11 RKO97592.1 - 8.3 6.5 10.0 6.6 6.8 0.4 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cofilin_ADF PF00241.20 RKO97593.1 - 8.3e-18 64.3 0.0 9.1e-18 64.2 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ski2_N PF17911.1 RKO97593.1 - 0.14 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Ski2 N-terminal region Oxidored_q6 PF01058.22 RKO97594.1 - 6.5e-22 77.8 0.0 9.5e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tmemb_14 PF03647.13 RKO97594.1 - 0.064 14.0 0.1 0.12 13.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C ELFV_dehydrog PF00208.21 RKO97595.1 - 2.6e-52 178.0 0.0 4.1e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 RKO97595.1 - 3.9e-26 91.0 0.0 2.9e-19 68.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 RKO97595.1 - 0.026 14.4 0.0 0.088 12.7 0.0 1.9 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Glyco_hydro_114 PF03537.13 RKO97595.1 - 0.05 12.9 0.0 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycoside-hydrolase family GH114 EB1 PF03271.17 RKO97596.1 - 3.8e-12 46.3 0.0 7e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 RKO97596.1 - 5.7e-06 26.5 0.2 9.4e-06 25.8 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain dCMP_cyt_deam_1 PF00383.23 RKO97597.1 - 2.2e-24 85.2 3.9 3.5e-24 84.6 3.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 RKO97597.1 - 8.1e-11 41.8 0.3 1.8e-10 40.7 0.3 1.5 1 1 0 1 1 1 1 MafB19-like deaminase APOBEC_N PF08210.11 RKO97597.1 - 0.022 14.7 1.2 0.036 13.9 1.2 1.4 1 0 0 1 1 1 0 APOBEC-like N-terminal domain SNAD4 PF18750.1 RKO97597.1 - 0.093 12.9 0.4 0.17 12.0 0.4 1.4 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 C2 PF00168.30 RKO97599.1 - 1.4e-20 73.5 0.0 1.7e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 RKO97599.1 - 0.001 18.6 0.0 0.078 12.5 0.0 2.1 1 1 0 1 1 1 1 CEP76 C2 domain NEAT PF05031.12 RKO97599.1 - 0.0097 16.5 0.1 0.012 16.2 0.1 1.2 1 0 0 1 1 1 1 Iron Transport-associated domain DAO PF01266.24 RKO97600.1 - 4.1e-40 138.4 5.0 3.2e-38 132.2 5.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Rieske PF00355.26 RKO97600.1 - 1.9e-11 43.7 0.0 5.4e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain FAD_binding_2 PF00890.24 RKO97600.1 - 3e-07 29.9 1.1 5.8e-07 28.9 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 RKO97600.1 - 1.7e-06 28.2 1.1 4.4e-06 26.8 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 RKO97600.1 - 7.4e-06 25.3 0.0 0.0006 19.0 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 RKO97600.1 - 1.6e-05 24.3 0.7 9.5e-05 21.8 0.7 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 RKO97600.1 - 0.00013 21.3 0.6 0.00023 20.5 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 RKO97600.1 - 0.00066 19.0 0.1 0.064 12.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 RKO97600.1 - 0.00081 18.2 1.1 0.00091 18.0 0.3 1.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 RKO97600.1 - 0.0025 17.8 0.3 0.53 10.3 0.2 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 RKO97600.1 - 0.005 16.3 2.1 0.023 14.0 2.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 RKO97600.1 - 0.011 14.9 0.6 0.076 12.1 0.2 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.6 RKO97600.1 - 0.017 15.6 0.1 0.041 14.3 0.1 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Amino_oxidase PF01593.24 RKO97600.1 - 0.019 14.2 0.0 1.3 8.2 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 RKO97600.1 - 0.022 15.3 0.3 0.082 13.5 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 RKO97600.1 - 0.037 13.3 0.1 0.061 12.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 RKO97600.1 - 0.048 12.9 0.0 0.098 11.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 RKO97600.1 - 0.058 13.7 0.4 0.14 12.5 0.4 1.6 1 0 0 1 1 1 0 TrkA-N domain Lactamase_B_2 PF12706.7 RKO97600.1 - 0.12 11.8 0.4 6.7 6.2 0.0 2.8 3 0 0 3 3 3 0 Beta-lactamase superfamily domain CUE PF02845.16 RKO97601.1 - 1.2e-06 28.1 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain HSP20 PF00011.21 RKO97602.1 - 4.3e-09 36.4 0.0 1.1e-06 28.7 0.0 2.1 1 1 1 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.16 RKO97602.1 - 0.0072 17.3 0.0 0.012 16.6 0.0 1.5 1 1 0 1 1 1 1 CS domain SecE PF00584.20 RKO97603.1 - 3.2e-13 49.4 0.0 4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CLP1_P PF16575.5 RKO97604.1 - 7.2e-32 110.7 0.0 7.9e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MMR_HSR1 PF01926.23 RKO97604.1 - 0.0062 16.6 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase UbiA PF01040.18 RKO97606.1 - 5.6e-29 101.2 21.4 7.1e-29 100.8 21.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ATXN-1_C PF12547.8 RKO97606.1 - 0.13 12.6 0.3 0.34 11.3 0.3 1.7 1 0 0 1 1 1 0 Capicua transcriptional repressor modulator TcpE PF12648.7 RKO97606.1 - 0.5 10.9 0.1 0.5 10.9 0.1 3.2 1 1 3 4 4 4 0 TcpE family ATP-synt_C PF00137.21 RKO97607.1 - 5e-30 103.6 32.9 9.6e-18 64.3 12.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C SPC22 PF04573.12 RKO97608.1 - 8.8e-34 116.4 1.0 9.5e-34 116.3 1.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF1494 PF07379.11 RKO97608.1 - 0.034 14.0 0.0 0.036 13.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1494) PKcGMP_CC PF16808.5 RKO97612.1 - 0.021 14.7 9.6 0.2 11.5 0.0 5.1 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Arm PF00514.23 RKO97615.1 - 7.6e-13 48.0 19.6 0.00055 19.9 0.0 8.3 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RKO97615.1 - 1.4e-09 38.2 7.5 0.0026 18.1 0.2 4.4 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 RKO97615.1 - 3.5e-07 30.4 0.1 0.012 15.7 0.0 3.8 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 RKO97615.1 - 5.2e-05 23.6 1.7 0.0096 16.4 0.1 4.9 4 0 0 4 4 4 1 HEAT-like repeat Adaptin_N PF01602.20 RKO97615.1 - 0.00016 20.4 0.1 0.017 13.7 0.0 2.9 2 1 1 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.13 RKO97615.1 - 0.0012 18.4 0.2 0.089 12.2 0.1 2.6 2 0 0 2 2 2 1 Armadillo-like ScsC_N PF18312.1 RKO97615.1 - 0.0078 16.0 0.7 0.021 14.7 0.7 1.7 1 0 0 1 1 1 1 Copper resistance protein ScsC N-terminal domain HEAT PF02985.22 RKO97615.1 - 0.031 14.5 17.8 1.1 9.7 0.0 8.1 9 0 0 9 9 9 0 HEAT repeat DUF4491 PF14898.6 RKO97615.1 - 0.072 13.5 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) Methyltr_RsmB-F PF01189.17 RKO97616.1 - 3.3e-70 235.8 0.0 5.7e-70 235.0 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 RKO97616.1 - 7.8e-12 45.5 0.0 1.6e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 RKO97616.1 - 0.00022 21.4 0.1 0.00042 20.5 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.16 RKO97616.1 - 0.0022 17.8 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DDHD PF02862.17 RKO97616.1 - 0.21 11.7 2.5 0.4 10.8 2.5 1.5 1 0 0 1 1 1 0 DDHD domain TRAPPC-Trs85 PF12739.7 RKO97616.1 - 1.6 7.6 8.3 3.3 6.6 8.3 1.4 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Presenilin PF01080.17 RKO97616.1 - 1.8 7.2 11.5 2.5 6.8 11.5 1.3 1 0 0 1 1 1 0 Presenilin Peptidase_S64 PF08192.11 RKO97616.1 - 6.6 5.1 6.5 9.4 4.6 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Cofilin_ADF PF00241.20 RKO97617.1 - 5.4e-17 61.7 0.0 9.5e-17 60.9 0.0 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Lar_N PF09861.9 RKO97617.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Lactate racemase N-terminal domain mit_SMPDase PF14724.6 RKO97618.1 - 0.91 7.4 2.9 1.8 6.4 0.3 2.2 2 0 0 2 2 2 0 Mitochondrial-associated sphingomyelin phosphodiesterase DUF1769 PF08588.10 RKO97619.1 - 5.4e-13 48.9 0.1 9.4e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Hist_deacetyl PF00850.19 RKO97620.1 - 1.4e-78 264.5 0.0 1.8e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain SGP PF17228.2 RKO97620.1 - 0.11 13.3 0.2 0.34 11.8 0.2 1.8 1 0 0 1 1 1 0 Sulphur globule protein SBDS PF01172.18 RKO97621.1 - 1.3e-07 31.6 0.0 2e-07 31.0 0.0 1.3 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SR-25 PF10500.9 RKO97622.1 - 0.039 13.6 16.9 0.053 13.1 16.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 RKO97622.1 - 0.39 10.6 70.7 0.57 10.1 70.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SART-1 PF03343.13 RKO97622.1 - 0.44 9.0 22.1 0.48 8.9 22.1 1.0 1 0 0 1 1 1 0 SART-1 family SMYLE_N PF18615.1 RKO97622.1 - 0.53 9.8 17.0 0.67 9.5 17.0 1.1 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Neur_chan_memb PF02932.16 RKO97622.1 - 0.59 10.2 19.3 0.73 9.8 19.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LAP1C PF05609.12 RKO97622.1 - 2.1 7.4 25.6 2.4 7.2 25.6 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 RKO97622.1 - 2.2 6.9 22.5 2.7 6.5 22.5 1.2 1 0 0 1 1 1 0 Hamartin protein Nop53 PF07767.11 RKO97622.1 - 2.8 7.2 24.1 3.3 7.0 24.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SID-1_RNA_chan PF13965.6 RKO97622.1 - 7.4 4.9 8.8 8.1 4.7 8.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4813 PF16072.5 RKO97623.1 - 3.7 7.1 29.1 4.6 6.8 29.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) COX5B PF01215.19 RKO97625.1 - 5.6e-25 87.5 0.0 6.1e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C4_Topoisom PF01396.19 RKO97625.1 - 0.014 15.1 0.7 2.8 7.8 0.1 2.3 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-CHCC PF10276.9 RKO97625.1 - 0.016 15.2 1.6 0.027 14.5 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger domain Cys_rich_CPXG PF14255.6 RKO97625.1 - 0.14 12.1 0.3 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 Cysteine-rich CPXCG 2-oxoacid_dh PF00198.23 RKO97626.1 - 2.7e-80 269.2 0.0 3.6e-80 268.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 RKO97626.1 - 6.7e-17 61.1 0.2 1.8e-16 59.7 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 RKO97626.1 - 7.4e-15 55.0 1.0 2.7e-14 53.2 1.0 2.1 1 0 0 1 1 1 1 e3 binding domain Apt1 PF10351.9 RKO97626.1 - 0.16 10.8 0.9 0.17 10.7 0.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF908 PF06012.12 RKO97626.1 - 0.8 9.1 8.7 1.2 8.5 8.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) MAGE_N PF12440.8 RKO97626.1 - 0.97 10.1 24.5 2.5 8.8 3.5 2.4 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal CCDC106 PF15794.5 RKO97626.1 - 1 9.0 3.2 1.7 8.3 3.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 Ndc1_Nup PF09531.10 RKO97626.1 - 3.5 6.2 4.9 5.6 5.5 4.9 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt5-NGN PF03439.13 RKO97627.1 - 6.7e-24 83.6 0.1 1.3e-23 82.6 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 RKO97627.1 - 5.7e-10 40.1 14.6 5.7e-10 40.1 14.6 2.7 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 RKO97627.1 - 1.1e-06 29.1 22.1 1.1e-06 29.1 22.1 3.5 1 1 1 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 RKO97627.1 - 3.1e-05 23.8 11.1 0.00097 19.0 2.8 4.4 5 0 0 5 5 5 2 KOW motif PGA2 PF07543.12 RKO97627.1 - 3.5 7.6 26.4 0.45 10.5 21.9 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF4667 PF15700.5 RKO97628.1 - 0.00018 21.7 2.6 0.00034 20.8 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) SR-25 PF10500.9 RKO97628.1 - 0.87 9.2 18.6 1.6 8.3 18.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SPX PF03105.19 RKO97628.1 - 9.2 6.1 8.3 13 5.6 8.3 1.2 1 0 0 1 1 1 0 SPX domain Serglycin PF04360.12 RKO97630.1 - 0.017 15.1 0.2 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 Serglycin Ribosomal_L37 PF08561.10 RKO97630.1 - 0.13 12.8 2.2 0.52 10.8 2.2 2.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 DEAD PF00270.29 RKO97631.1 - 6.4e-46 156.3 0.5 6.4e-46 156.3 0.5 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO97631.1 - 3.7e-32 111.0 2.3 6.7e-31 106.9 0.2 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO97631.1 - 7.1e-09 35.9 0.2 1.6e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RKO97631.1 - 1.1e-05 25.9 0.1 0.0047 17.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 RKO97631.1 - 0.0012 18.7 0.0 0.0022 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 RKO97631.1 - 0.0053 16.7 0.2 0.031 14.3 0.1 2.3 1 1 1 2 2 2 1 Flavivirus DEAD domain CMS1 PF14617.6 RKO97631.1 - 0.0062 15.9 0.3 0.034 13.5 0.0 2.1 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 RKO97631.1 - 0.01 16.1 0.5 0.048 13.9 0.2 2.3 2 1 0 2 2 2 0 AAA domain Helicase_RecD PF05127.14 RKO97631.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Helicase Phage_integrase PF00589.22 RKO97631.1 - 0.084 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family WD40 PF00400.32 RKO97632.1 - 8.7e-21 73.9 25.5 0.0089 16.9 0.0 10.3 10 1 0 10 10 10 7 WD domain, G-beta repeat zf-Tim10_DDP PF02953.15 RKO97633.1 - 1.8e-18 65.9 0.2 2e-18 65.8 0.2 1.0 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WD40 PF00400.32 RKO97634.1 - 0.0024 18.7 4.2 26 5.9 0.1 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat LisH PF08513.11 RKO97634.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 LisH Ribonuclease_T2 PF00445.18 RKO97635.1 - 5.7e-17 62.5 0.0 6.2e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease T2 family DUF4349 PF14257.6 RKO97635.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Pkinase PF00069.25 RKO97636.1 - 1.7e-64 217.7 0.0 2e-64 217.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97636.1 - 4e-50 170.5 0.0 4.9e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97636.1 - 0.00076 18.9 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 RKO97636.1 - 0.0011 17.9 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase TSCPD PF12637.7 RKO97636.1 - 0.0037 17.5 0.1 0.0081 16.4 0.1 1.5 1 0 0 1 1 1 1 TSCPD domain Haspin_kinase PF12330.8 RKO97636.1 - 0.015 14.3 0.3 0.26 10.2 0.3 2.0 1 1 0 1 1 1 0 Haspin like kinase domain KIND PF16474.5 RKO97636.1 - 0.015 15.2 0.1 0.05 13.5 0.0 1.9 2 0 0 2 2 2 0 Kinase non-catalytic C-lobe domain APH PF01636.23 RKO97636.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family PI3_PI4_kinase PF00454.27 RKO97637.1 - 6.6e-46 157.2 0.0 9.4e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Homeobox_KN PF05920.11 RKO97638.1 - 8.7e-17 60.7 0.5 1.1e-16 60.4 0.5 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 RKO97638.1 - 4.1e-07 29.7 0.3 5.1e-07 29.5 0.3 1.1 1 0 0 1 1 1 1 Homeodomain COX6A PF02046.15 RKO97639.1 - 8e-11 42.4 0.5 9.6e-11 42.2 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DNA_topoisoIV PF00521.20 RKO97640.1 - 3.3e-129 431.5 0.0 5.1e-129 430.9 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 RKO97640.1 - 6.5e-47 159.0 0.4 6.5e-47 159.0 0.4 2.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 RKO97640.1 - 1.4e-19 70.2 0.0 3.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 RKO97640.1 - 4.1e-12 46.6 0.0 9.8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 RKO97640.1 - 7.9e-08 32.5 0.0 3.1e-07 30.6 0.0 2.0 1 0 0 1 1 1 1 Toprim domain DUF4174 PF13778.6 RKO97640.1 - 0.091 13.2 0.1 0.28 11.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Glyco_hydro_65C PF03633.15 RKO97640.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain BBIP10 PF14777.6 RKO97640.1 - 0.12 12.0 0.3 0.31 10.6 0.3 1.7 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 DNA_gyraseB_C PF00986.21 RKO97640.1 - 0.13 12.4 0.0 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus UPF0029 PF01205.19 RKO97641.1 - 1.1e-29 102.9 0.0 1.2e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 TRAPPC-Trs85 PF12739.7 RKO97642.1 - 2.1e-71 241.1 0.0 1.7e-70 238.1 0.0 2.3 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF2059 PF09832.9 RKO97642.1 - 0.077 13.1 1.8 0.14 12.2 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) Acyltransferase PF01553.21 RKO97643.1 - 2.1e-32 111.5 0.0 3e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase HALZ PF02183.18 RKO97647.1 - 7.4e-11 42.1 12.1 0.0042 17.3 0.9 4.8 1 1 4 5 5 5 3 Homeobox associated leucine zipper ZapB PF06005.12 RKO97647.1 - 5.5e-06 26.7 19.7 0.0069 16.8 1.5 3.2 1 1 2 3 3 3 3 Cell division protein ZapB APG6_N PF17675.1 RKO97647.1 - 1.7e-05 25.3 22.3 0.0006 20.4 22.3 2.0 1 1 0 1 1 1 1 Apg6 coiled-coil region JIP_LZII PF16471.5 RKO97647.1 - 3.3e-05 24.0 19.7 0.047 13.9 0.6 4.3 1 1 4 5 5 5 4 JNK-interacting protein leucine zipper II CENP-F_leu_zip PF10473.9 RKO97647.1 - 0.00023 21.2 17.9 0.0012 18.9 6.9 2.0 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IES5 PF17335.2 RKO97647.1 - 0.00058 20.1 6.0 0.00058 20.1 6.0 2.7 1 1 2 3 3 3 1 Ino80 complex subunit 5 bZIP_1 PF00170.21 RKO97647.1 - 0.0016 18.5 10.2 1.4 9.1 0.5 3.7 1 1 2 3 3 3 1 bZIP transcription factor Macoilin PF09726.9 RKO97647.1 - 0.0023 16.6 15.4 0.0088 14.7 15.4 1.7 1 1 0 1 1 1 1 Macoilin family Spc7 PF08317.11 RKO97647.1 - 0.0028 16.6 17.4 0.03 13.2 17.4 2.1 1 1 0 1 1 1 1 Spc7 kinetochore protein DUF4472 PF14739.6 RKO97647.1 - 0.0036 18.0 19.7 0.024 15.4 6.0 2.7 1 1 2 3 3 3 2 Domain of unknown function (DUF4472) GIT_CC PF16559.5 RKO97647.1 - 0.0036 17.1 19.0 0.42 10.5 4.3 4.0 1 1 1 3 3 3 2 GIT coiled-coil Rho guanine nucleotide exchange factor KASH_CCD PF14662.6 RKO97647.1 - 0.0059 16.4 17.2 0.063 13.1 17.2 2.1 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF4201 PF13870.6 RKO97647.1 - 0.0096 15.7 17.2 0.29 10.8 1.6 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) Seadorna_VP6 PF07407.11 RKO97647.1 - 0.015 14.3 3.5 0.035 13.1 1.2 2.0 1 1 1 2 2 2 0 Seadornavirus VP6 protein DUF2205 PF10224.9 RKO97647.1 - 0.017 15.1 9.4 1.6 8.8 0.5 3.7 1 1 2 3 3 3 0 Short coiled-coil protein Scaffolding_pro PF11418.8 RKO97647.1 - 0.021 15.4 10.9 0.92 10.1 0.6 3.4 1 1 2 3 3 3 0 Phi29 scaffolding protein ATG16 PF08614.11 RKO97647.1 - 0.022 15.0 24.3 0.58 10.3 8.5 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ERM PF00769.19 RKO97647.1 - 0.045 13.6 18.1 0.038 13.8 15.8 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family GAS PF13851.6 RKO97647.1 - 0.054 12.8 17.6 0.35 10.2 6.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Taxilin PF09728.9 RKO97647.1 - 0.06 12.5 20.2 0.15 11.2 14.7 2.6 1 1 1 2 2 2 0 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 RKO97647.1 - 0.072 13.3 18.0 0.12 12.6 2.1 2.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF724 PF05266.14 RKO97647.1 - 0.072 12.9 15.2 0.34 10.7 9.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) SHE3 PF17078.5 RKO97647.1 - 0.14 11.9 16.1 0.56 9.9 6.2 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 CtIP_N PF10482.9 RKO97647.1 - 0.17 12.0 11.9 0.061 13.4 7.9 2.2 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain USP19_linker PF16602.5 RKO97647.1 - 0.2 12.2 7.8 2.8 8.5 0.6 2.5 1 1 1 2 2 2 0 Linker region of USP19 deubiquitinase YabA PF06156.13 RKO97647.1 - 0.25 12.0 15.7 5.8e+02 1.2 15.7 2.6 1 1 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 RKO97647.1 - 0.26 10.6 9.6 0.36 10.1 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 RKO97647.1 - 0.28 11.6 21.0 0.53 10.7 8.9 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Cep57_CLD_2 PF14197.6 RKO97647.1 - 0.29 11.2 13.0 29 4.8 5.3 3.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DUF1968 PF09291.10 RKO97647.1 - 0.35 11.0 3.6 2 8.6 0.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF1968) HAUS-augmin3 PF14932.6 RKO97647.1 - 0.39 10.3 25.0 4.2 6.9 7.0 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 WXG100 PF06013.12 RKO97647.1 - 0.39 11.0 14.5 2.5 8.4 1.5 3.8 1 1 4 5 5 5 0 Proteins of 100 residues with WXG Jnk-SapK_ap_N PF09744.9 RKO97647.1 - 0.43 10.8 25.6 0.16 12.2 6.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 RKO97647.1 - 0.53 10.7 17.1 0.89 10.0 17.1 1.4 1 1 0 1 1 1 0 Fez1 Seryl_tRNA_N PF02403.22 RKO97647.1 - 0.89 9.8 4.8 5.2 7.3 0.7 2.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF2968 PF11180.8 RKO97647.1 - 0.93 9.1 18.8 0.33 10.5 8.8 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Nmad5 PF18757.1 RKO97647.1 - 1 9.5 8.9 0.22 11.7 1.5 2.2 1 1 1 2 2 2 0 Nucleotide modification associated domain 5 DUF5595 PF18077.1 RKO97647.1 - 1.6 8.8 7.7 27 5.0 0.0 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF5595) SNAPc19 PF15497.6 RKO97647.1 - 1.7 9.2 19.9 0.75 10.3 9.7 2.2 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 LPP PF04728.13 RKO97647.1 - 2.1 8.8 7.6 17 5.9 0.1 3.2 1 1 1 3 3 3 0 Lipoprotein leucine-zipper FapA PF03961.13 RKO97647.1 - 2.3 6.7 6.4 2.9 6.4 6.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A ADIP PF11559.8 RKO97647.1 - 2.5 8.2 28.3 10 6.2 12.6 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Phage_tail_T PF06223.12 RKO97647.1 - 3.5 8.2 5.2 3.5 8.2 1.3 2.1 1 1 1 2 2 2 0 Minor tail protein T Spc24 PF08286.11 RKO97647.1 - 4.8 7.5 19.6 1.8e+04 -5.7 19.6 3.2 1 1 0 1 1 0 0 Spc24 subunit of Ndc80 Prok-TraM PF09228.10 RKO97647.1 - 4.9 7.6 11.1 8.4 6.8 2.5 2.6 1 1 2 3 3 3 0 Prokaryotic Transcriptional repressor TraM DUF5320 PF17253.2 RKO97647.1 - 7.2 7.8 11.3 1.1e+04 -2.4 11.3 3.7 1 1 0 1 1 0 0 Family of unknown function (DUF5320) Kinesin PF00225.23 RKO97648.1 - 4.7e-85 285.5 0.0 5.7e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 RKO97648.1 - 1.2e-16 60.9 0.0 3.6e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding AAA_7 PF12775.7 RKO97648.1 - 0.22 11.0 0.1 0.93 9.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region PMI_typeI PF01238.21 RKO97649.1 - 9.8e-116 387.0 0.0 1.1e-115 386.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 RKO97649.1 - 4.7e-05 23.0 0.0 0.057 13.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.7 RKO97649.1 - 0.013 15.2 3.2 8.4 6.1 0.1 3.6 4 0 0 4 4 4 0 Cupin Gln-synt_C PF00120.24 RKO97650.1 - 9e-81 271.5 0.0 1.2e-80 271.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 RKO97650.1 - 1.6e-05 24.7 0.0 2.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 RKO97650.1 - 0.00037 20.2 1.0 0.0039 16.9 1.0 2.2 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain NUDIX PF00293.28 RKO97651.1 - 2.3e-05 24.4 0.1 4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain AhpC-TSA PF00578.21 RKO97652.1 - 1.3e-26 92.9 0.0 1.4e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 RKO97652.1 - 7.8e-17 61.3 0.0 8.2e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 RKO97652.1 - 0.0038 17.3 0.0 0.011 15.8 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme Alg6_Alg8 PF03155.15 RKO97653.1 - 5.8e-99 332.2 23.7 7.9e-99 331.8 23.7 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Methyltransf_32 PF13679.6 RKO97655.1 - 2e-20 73.4 0.0 3.1e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain IPTL-CTERM PF18203.1 RKO97656.1 - 0.39 10.7 2.3 1 9.3 2.3 1.7 1 0 0 1 1 1 0 IPTL-CTERM motif DHR-2 PF06920.13 RKO97657.1 - 1.1e-60 205.9 0.0 1.4e-60 205.5 0.0 1.1 1 0 0 1 1 1 1 Dock homology region 2 Paf67 PF10255.9 RKO97658.1 - 2.1e-86 290.4 0.0 2.5e-86 290.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_1 PF00515.28 RKO97658.1 - 0.011 15.5 0.0 0.043 13.6 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 RKO97658.1 - 0.014 15.5 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Stealth_CR4 PF17103.5 RKO97658.1 - 0.08 12.8 1.0 0.26 11.2 1.0 1.8 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 Suc_Fer-like PF06999.12 RKO97659.1 - 1.5e-39 135.9 0.0 2e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Pam16 PF03656.13 RKO97659.1 - 1.8 8.6 4.0 3.3 7.8 4.0 1.3 1 0 0 1 1 1 0 Pam16 VCX_VCY PF15231.6 RKO97660.1 - 1.2 9.8 11.8 0.24 12.1 7.7 2.0 2 0 0 2 2 2 0 Variable charge X/Y family PCI PF01399.27 RKO97661.1 - 0.0023 18.4 0.0 0.084 13.4 0.0 2.9 2 0 0 2 2 2 1 PCI domain ANAPC4_WD40 PF12894.7 RKO97662.1 - 1.3e-13 51.0 0.3 0.035 14.4 0.0 6.6 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKO97662.1 - 2.1e-12 47.3 0.6 4.4 8.3 0.1 7.5 7 0 0 7 7 7 3 WD domain, G-beta repeat eIF2A PF08662.11 RKO97662.1 - 1e-05 25.5 0.0 11 5.9 0.0 5.3 4 2 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 RKO97662.1 - 0.00026 20.8 3.9 3 7.9 0.1 5.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Lactonase PF10282.9 RKO97662.1 - 0.04 13.2 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller IKI3 PF04762.12 RKO97662.1 - 0.045 11.8 0.1 11 3.8 0.0 3.6 2 1 1 4 4 4 0 IKI3 family DPPIV_N PF00930.21 RKO97662.1 - 0.57 8.9 2.0 55 2.4 0.0 3.7 3 2 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region GTP_EFTU PF00009.27 RKO97663.1 - 1e-61 207.9 0.0 1.9e-61 207.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 RKO97663.1 - 4.9e-42 142.5 0.3 3.2e-41 139.9 0.1 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 RKO97663.1 - 1.6e-29 101.8 0.0 3.4e-29 100.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 RKO97663.1 - 8.3e-23 80.2 0.0 2.4e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 RKO97663.1 - 2.8e-10 40.4 0.1 1.7e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 RKO97663.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 RKO97663.1 - 0.0011 19.0 0.1 0.003 17.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 RKO97663.1 - 0.02 14.3 0.0 0.065 12.6 0.0 1.7 2 0 0 2 2 2 0 AIG1 family FeoB_N PF02421.18 RKO97663.1 - 0.068 12.7 0.0 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 RKO97663.1 - 0.076 12.4 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1949 PF09186.11 RKO97663.1 - 0.08 12.8 0.0 0.24 11.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) 2OG-FeII_Oxy_2 PF13532.6 RKO97664.1 - 3.1e-20 73.2 0.0 4.3e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily eIF-5_eIF-2B PF01873.17 RKO97665.1 - 2.2e-40 137.2 0.0 3.2e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 RKO97665.1 - 0.02 14.4 0.3 0.033 13.7 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding IF2_N PF04760.15 RKO97665.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Mito_carr PF00153.27 RKO97666.1 - 3.8e-63 209.4 0.8 1.1e-20 73.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ATP-synt_C PF00137.21 RKO97667.1 - 1.4e-27 95.8 31.5 2.2e-16 60.0 7.2 2.6 3 0 0 3 3 3 2 ATP synthase subunit C RhoGEF PF00621.20 RKO97668.1 - 1.5e-25 90.5 0.0 2.8e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain SH3_9 PF14604.6 RKO97668.1 - 9.5e-09 35.0 0.2 2.4e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 RKO97668.1 - 3e-07 30.0 0.0 6.4e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO97668.1 - 7.1e-07 28.7 0.9 1.2e-06 28.0 0.2 1.9 2 0 0 2 2 2 1 SH3 domain BAR PF03114.18 RKO97668.1 - 3.4e-06 26.9 3.9 0.00075 19.2 1.0 2.4 2 0 0 2 2 2 2 BAR domain Pkinase PF00069.25 RKO97669.1 - 1.7e-51 175.1 0.0 1.9e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97669.1 - 2.9e-24 85.8 0.0 3.3e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97669.1 - 1.4e-07 31.1 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 RKO97669.1 - 0.00057 19.9 0.6 0.0064 16.4 0.2 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 RKO97669.1 - 0.01 15.2 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Voldacs PF03517.13 RKO97671.1 - 2.8e-14 53.4 0.2 4.9e-14 52.6 0.2 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Flavoprotein PF02441.19 RKO97672.1 - 7e-45 152.6 0.2 8.5e-45 152.3 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein Herpes_UL37_1 PF03970.13 RKO97672.1 - 0.04 13.1 0.1 0.065 12.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein tRNA-synt_1e PF01406.19 RKO97673.1 - 7.6e-127 422.8 0.0 1.2e-126 422.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 RKO97673.1 - 1.4e-07 30.6 2.2 0.00011 21.1 0.1 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 RKO97673.1 - 3.4e-05 22.3 0.0 0.00028 19.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 RKO97673.1 - 5.9e-05 23.5 0.1 5.9e-05 23.5 0.1 2.6 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.21 RKO97673.1 - 0.05 12.5 2.1 0.12 11.3 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain PA PF02225.22 RKO97673.1 - 0.16 12.0 0.0 0.57 10.3 0.0 1.9 1 0 0 1 1 1 0 PA domain DUF2062 PF09835.9 RKO97674.1 - 0.043 13.7 0.2 0.079 12.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Vfa1 PF08432.10 RKO97675.1 - 0.48 10.7 8.3 0.87 9.9 8.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Exonuc_VII_L PF02601.15 RKO97675.1 - 0.69 9.4 17.2 1.3 8.5 17.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit COesterase PF00135.28 RKO97675.1 - 0.78 8.5 4.6 1.1 8.0 4.6 1.2 1 0 0 1 1 1 0 Carboxylesterase family Spt20 PF12090.8 RKO97675.1 - 3 7.4 20.2 6 6.4 20.2 1.5 1 0 0 1 1 1 0 Spt20 family Sugar_tr PF00083.24 RKO97676.1 - 3.7e-121 405.1 25.3 4.2e-121 405.0 25.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 RKO97676.1 - 1.6e-28 99.7 45.1 3e-24 85.6 17.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 RKO97676.1 - 2.4e-06 26.7 17.6 0.0054 15.6 4.1 2.6 1 1 2 3 3 3 2 MFS_1 like family TRI12 PF06609.13 RKO97676.1 - 0.00024 19.7 4.2 0.00024 19.7 4.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TMEM100 PF16311.5 RKO97676.1 - 0.39 10.3 4.3 0.17 11.5 1.2 2.0 1 1 1 2 2 2 0 Transmembrane protein 100 UNC-93 PF05978.16 RKO97676.1 - 1.2 8.8 16.4 0.017 14.9 5.7 2.6 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 OATP PF03137.20 RKO97676.1 - 2.6 6.2 8.1 0.78 8.0 4.5 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ras PF00071.22 RKO97677.1 - 2.9e-46 157.0 0.0 3.2e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO97677.1 - 9.2e-16 58.1 0.0 1.2e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO97677.1 - 2e-05 24.1 0.0 2.4e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO97677.1 - 0.00015 21.3 0.1 0.0007 19.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 RKO97677.1 - 0.00018 21.4 0.0 0.026 14.4 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 RKO97677.1 - 0.0031 17.6 0.0 0.0043 17.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 RKO97677.1 - 0.034 14.2 0.0 0.054 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 RKO97677.1 - 0.056 13.0 0.0 0.19 11.2 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 RKO97677.1 - 0.067 13.2 0.0 0.098 12.7 0.0 1.3 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Poxvirus PF06227.12 RKO97677.1 - 0.11 12.3 0.3 0.38 10.5 0.3 1.7 2 0 0 2 2 2 0 dsDNA Poxvirus Motile_Sperm PF00635.26 RKO97678.1 - 3.7e-20 71.8 0.0 4.5e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 RKO97678.1 - 0.0024 18.0 0.0 0.0031 17.7 0.0 1.1 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin HSP20 PF00011.21 RKO97679.1 - 7e-09 35.8 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.16 RKO97679.1 - 0.00024 22.0 0.0 0.00032 21.6 0.0 1.2 1 0 0 1 1 1 1 CS domain Vma12 PF11712.8 RKO97679.1 - 0.035 14.2 0.2 0.053 13.6 0.2 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Mito_carr PF00153.27 RKO97680.1 - 1.3e-65 217.3 2.2 8.8e-23 80.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Nodulin PF02451.15 RKO97680.1 - 0.15 11.6 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Nodulin S-AdoMet_synt_C PF02773.16 RKO97681.1 - 1.7e-66 222.4 0.2 1.7e-66 222.4 0.2 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 RKO97681.1 - 1.4e-44 150.8 1.6 3.4e-44 149.5 0.3 2.1 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 RKO97681.1 - 2.7e-44 150.2 0.0 6.2e-44 149.1 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 RKO97681.1 - 0.051 12.4 0.2 0.12 11.1 0.1 1.5 1 1 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) Methyltransf_25 PF13649.6 RKO97683.1 - 4.2e-13 49.8 0.0 1.8e-12 47.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO97683.1 - 1.7e-11 44.1 0.0 2.6e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO97683.1 - 1.8e-11 44.5 0.0 5.2e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 RKO97683.1 - 5.5e-11 42.4 0.0 8.8e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 RKO97683.1 - 5.5e-07 29.6 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKO97683.1 - 1.1e-06 28.3 0.0 2.3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 RKO97683.1 - 9e-06 25.2 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 RKO97683.1 - 3.5e-05 24.5 0.1 0.00067 20.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 RKO97683.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 RKO97683.1 - 0.00035 20.0 0.0 0.0006 19.2 0.0 1.5 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 RKO97683.1 - 0.00071 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 RKO97683.1 - 0.0014 18.4 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.6 RKO97683.1 - 0.0078 16.2 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 RKO97683.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 FtsJ PF01728.19 RKO97683.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 RKO97683.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 RKO97683.1 - 0.048 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 RKO97683.1 - 0.068 14.2 0.4 0.43 11.6 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 RKO97683.1 - 0.075 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 RKO97683.1 - 0.076 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF676 PF05057.14 RKO97684.1 - 2.6e-18 66.3 0.0 2.6e-18 66.3 0.0 1.0 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 RKO97684.1 - 0.0031 18.1 0.2 0.0036 17.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 RKO97684.1 - 0.011 15.6 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase PGAP1 PF07819.13 RKO97684.1 - 0.012 15.4 0.0 0.014 15.2 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.22 RKO97684.1 - 0.068 13.1 0.0 0.079 12.9 0.0 1.1 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 RKO97684.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 RKO97684.1 - 0.28 10.3 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Pkinase PF00069.25 RKO97685.1 - 6e-73 245.4 0.0 6.8e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97685.1 - 5.6e-34 117.6 0.0 7.6e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97685.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 RKO97685.1 - 0.0055 15.7 0.0 0.03 13.3 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 RKO97685.1 - 0.052 12.9 0.5 0.1 11.9 0.5 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fcf1 PF04900.12 RKO97686.1 - 2.1e-34 117.9 1.5 2.1e-34 117.9 1.5 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 RKO97686.1 - 3.2e-07 30.7 0.2 1.5e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 PIN like domain G-alpha PF00503.20 RKO97687.1 - 8.1e-113 377.2 0.9 1e-112 376.9 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 RKO97687.1 - 8.4e-17 61.2 2.1 1.6e-11 44.0 0.0 3.4 3 0 0 3 3 3 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 RKO97687.1 - 8e-05 22.1 0.2 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 RKO97687.1 - 0.00025 21.3 0.6 0.39 10.9 0.1 2.7 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 RKO97687.1 - 0.043 13.6 0.5 0.11 12.3 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain SMP_C2CD2L PF18696.1 RKO97687.1 - 0.091 12.6 0.2 0.83 9.5 0.0 2.3 3 0 0 3 3 3 0 Synaptotagmin-like, mitochondrial and lipid-binding domain MMR_HSR1 PF01926.23 RKO97687.1 - 0.15 12.2 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase EMP24_GP25L PF01105.24 RKO97688.1 - 8.3e-34 117.1 0.0 9.5e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TSC22 PF01166.18 RKO97688.1 - 0.095 13.0 0.5 0.18 12.1 0.5 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family TBK1_ULD PF18396.1 RKO97688.1 - 0.14 12.1 0.7 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Pkinase PF00069.25 RKO97689.1 - 4.3e-67 226.3 0.0 5.2e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97689.1 - 6.4e-31 107.6 0.0 8.9e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 RKO97689.1 - 4.8e-05 22.5 0.0 6.6e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 RKO97689.1 - 0.00019 20.9 0.0 0.0017 17.7 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 RKO97689.1 - 0.00059 19.2 0.1 0.0022 17.4 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 RKO97689.1 - 0.005 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 RKO97689.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 RKO97689.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 RKO97689.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase 60KD_IMP PF02096.20 RKO97690.1 - 7.7e-15 55.2 0.0 1.8e-13 50.7 0.0 2.0 2 0 0 2 2 2 2 60Kd inner membrane protein Tfb5 PF06331.12 RKO97691.1 - 1.9e-25 88.7 1.7 2e-25 88.5 1.7 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 HORMA PF02301.18 RKO97693.1 - 4e-23 82.1 0.1 5.8e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 RKO97693.1 - 0.006 16.4 0.1 0.013 15.4 0.1 1.6 1 0 0 1 1 1 1 Bacterial HORMA domain 2 Rota_NSP3 PF01665.16 RKO97693.1 - 0.025 13.7 0.2 0.034 13.3 0.2 1.1 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 ATG13 PF10033.9 RKO97693.1 - 0.063 13.0 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 DEAD PF00270.29 RKO97694.1 - 1.5e-15 57.4 0.0 3.3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO97694.1 - 6.9e-11 42.5 0.0 7.5e-10 39.1 0.0 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Sds3 PF08598.11 RKO97695.1 - 0.6 10.1 6.2 1 9.3 6.2 1.3 1 0 0 1 1 1 0 Sds3-like DAGK_acc PF00609.19 RKO97696.1 - 2.7e-35 122.1 0.0 1.5e-16 61.1 0.0 2.2 2 0 0 2 2 2 2 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 RKO97696.1 - 3.3e-19 68.8 0.0 6.6e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 RKO97696.1 - 3e-07 30.2 19.3 1.3e-06 28.2 5.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) LRR_6 PF13516.6 RKO97696.1 - 0.14 12.2 0.0 7.9 6.8 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeat DUF2236 PF09995.9 RKO97697.1 - 2.9e-22 80.0 10.4 3.9e-22 79.6 9.4 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) PDEase_I PF00233.19 RKO97698.1 - 0.00057 19.7 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Cyclin PF08613.11 RKO97698.1 - 0.0076 16.6 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 Cyclin Fumble PF03630.14 RKO97700.1 - 4e-130 433.8 0.2 7.3e-130 433.0 0.2 1.4 1 1 0 1 1 1 1 Fumble DUF89 PF01937.19 RKO97700.1 - 9.9e-32 110.3 0.0 1.5e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF89 Tcp10_C PF07202.13 RKO97701.1 - 1e-41 142.8 0.1 1.4e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 T-complex protein 10 C-terminus HCBP_related PF06594.11 RKO97701.1 - 0.0091 15.9 0.1 1.4 8.9 0.1 2.5 2 0 0 2 2 2 1 Haemolysin-type calcium binding protein related domain FlxA PF14282.6 RKO97701.1 - 0.1 12.6 4.0 0.16 12.0 0.5 2.2 2 0 0 2 2 2 0 FlxA-like protein Spc29 PF17082.5 RKO97701.1 - 0.36 10.7 7.7 0.7 9.7 5.5 2.0 1 1 1 2 2 2 0 Spindle Pole Component 29 GIT_CC PF16559.5 RKO97701.1 - 1.8 8.5 3.9 24 4.9 0.1 2.9 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 RKO97701.1 - 2.6 7.3 10.5 4.6 6.5 10.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 RKO97701.1 - 8.3 5.2 17.6 20 4.0 17.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein TPR_19 PF14559.6 RKO97702.1 - 3e-18 66.1 13.1 0.0046 17.4 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 RKO97702.1 - 5.3e-17 61.1 60.0 4.1e-05 24.0 0.2 14.3 5 4 11 16 16 16 6 Tetratricopeptide repeat HAT PF02184.16 RKO97702.1 - 1.1e-14 54.1 50.6 0.00029 20.7 0.8 12.4 11 2 0 11 11 10 4 HAT (Half-A-TPR) repeat Suf PF05843.14 RKO97702.1 - 1.5e-13 51.4 1.2 0.002 18.2 0.0 5.7 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 RKO97702.1 - 2.5e-07 30.7 11.4 0.063 13.3 0.8 7.2 6 3 1 7 7 7 1 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 RKO97702.1 - 1.1e-06 28.0 26.0 0.0088 15.3 2.4 5.5 1 1 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 RKO97702.1 - 1.7e-06 27.7 13.3 14 6.1 0.0 9.7 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKO97702.1 - 4.1e-05 23.9 18.0 1.3 9.8 0.1 9.1 10 0 0 10 10 8 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 RKO97702.1 - 0.0003 20.8 4.1 1.2 9.2 0.0 5.1 4 2 2 6 6 6 1 U3 small nucleolar RNA-associated protein 6 MIT PF04212.18 RKO97702.1 - 0.00091 19.2 3.0 0.85 9.7 0.0 4.5 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 RKO97702.1 - 0.0023 17.9 15.8 0.75 10.0 0.0 7.7 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 RKO97702.1 - 0.0077 16.5 2.8 4.4 7.9 0.0 6.2 8 0 0 8 8 7 1 Tetratricopeptide repeat Babuvirus_MP PF07234.11 RKO97702.1 - 0.023 14.9 1.0 1.4 9.1 0.1 3.2 2 1 1 3 3 3 0 Movement and RNA silencing protein AF-4 PF05110.13 RKO97702.1 - 0.033 12.3 3.9 0.043 11.9 3.9 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UCH PF00443.29 RKO97703.1 - 3.9e-46 157.6 0.0 5.2e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 RKO97703.1 - 9.8e-28 97.1 0.0 2e-27 96.0 0.0 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 RKO97703.1 - 8.7e-23 81.4 0.0 5.5e-22 78.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PRP1_N PF06424.12 RKO97704.1 - 1.7e-34 119.4 0.3 3e-34 118.5 0.3 1.4 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 RKO97704.1 - 4.7e-13 48.8 112.4 0.0021 18.7 0.6 16.9 5 3 12 18 18 16 10 Tetratricopeptide repeat TPR_19 PF14559.6 RKO97704.1 - 1.8e-10 41.2 70.2 3.9e-05 24.1 0.3 10.8 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 RKO97704.1 - 1.1e-06 29.2 5.4 1.1e-06 29.2 5.4 10.6 8 2 2 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 RKO97704.1 - 3.6e-06 27.0 4.3 0.97 10.0 0.1 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKO97704.1 - 1.1e-05 25.2 13.1 6.9 7.0 0.1 9.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 RKO97704.1 - 0.00094 19.2 0.0 13 6.3 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat PPR_long PF17177.4 RKO97704.1 - 0.01 15.2 0.7 0.6 9.4 0.1 2.8 2 1 1 3 3 3 0 Pentacotripeptide-repeat region of PRORP NARP1 PF12569.8 RKO97704.1 - 0.032 13.2 5.0 3.3 6.5 0.1 3.7 5 0 0 5 5 5 0 NMDA receptor-regulated protein 1 baeRF_family12 PF18856.1 RKO97704.1 - 0.048 14.2 1.6 0.11 13.1 1.6 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 TPR_7 PF13176.6 RKO97704.1 - 2.3 8.5 6.4 61 4.0 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Dehydrin PF00257.19 RKO97704.1 - 3 8.4 9.2 0.16 12.5 2.7 2.2 2 0 0 2 2 2 0 Dehydrin DASH_Dad1 PF08649.10 RKO97705.1 - 0.07 13.3 0.7 0.54 10.5 0.8 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad1 Shugoshin_N PF07558.11 RKO97705.1 - 2.3 8.1 5.6 7.7 6.5 0.5 3.7 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region WD40 PF00400.32 RKO97706.1 - 0.0028 18.5 0.1 0.13 13.1 0.1 3.3 2 1 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97706.1 - 0.031 14.6 0.0 0.16 12.3 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ndc80_HEC PF03801.13 RKO97707.1 - 1.2e-46 158.1 0.0 3.6e-46 156.6 0.0 1.8 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 RKO97707.1 - 2.2e-09 37.3 0.0 2.2e-09 37.3 0.0 4.2 4 1 1 5 5 5 1 Domain of unknown function (DUF5595) Spc7 PF08317.11 RKO97707.1 - 0.0033 16.4 8.5 0.0033 16.4 8.5 2.7 2 1 0 2 2 2 1 Spc7 kinetochore protein IFT57 PF10498.9 RKO97707.1 - 0.088 11.8 25.2 0.042 12.8 3.4 3.0 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 PI_PP_I PF18363.1 RKO97707.1 - 0.095 12.9 6.4 0.1 12.8 0.3 3.2 3 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain DUF4407 PF14362.6 RKO97707.1 - 0.32 10.3 23.6 0.21 10.9 10.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 RKO97707.1 - 0.39 10.7 30.9 0.027 14.5 6.5 4.0 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 RKO97707.1 - 0.53 9.6 34.7 0.073 12.4 10.4 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 RKO97707.1 - 0.58 10.6 27.4 0.62 10.5 8.4 2.6 2 1 0 2 2 2 0 Fez1 WXG100 PF06013.12 RKO97707.1 - 0.92 9.8 0.0 0.92 9.8 0.0 5.4 5 1 0 5 5 5 0 Proteins of 100 residues with WXG UPF0242 PF06785.11 RKO97707.1 - 0.93 9.6 41.6 1.4 9.0 8.5 4.0 2 2 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 RKO97707.1 - 0.99 9.9 15.6 0.038 14.4 3.2 3.9 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 RKO97707.1 - 1.4 8.8 20.8 0.032 14.0 1.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF724) OmpH PF03938.14 RKO97707.1 - 3.8 7.8 30.4 1.6 9.0 4.5 3.9 2 2 1 3 3 3 0 Outer membrane protein (OmpH-like) COG2 PF06148.11 RKO97707.1 - 4.5 7.4 17.8 0.037 14.1 2.4 3.4 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4665 PF15679.5 RKO97707.1 - 4.9 7.8 11.9 0.88 10.2 1.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) COG5 PF10392.9 RKO97707.1 - 5.3 7.2 20.5 0.14 12.3 4.2 3.0 2 1 0 2 2 2 0 Golgi transport complex subunit 5 Syntaxin PF00804.25 RKO97707.1 - 9.1 5.9 22.7 2.3 7.8 9.4 2.9 2 1 0 2 2 2 0 Syntaxin COPIIcoated_ERV PF07970.12 RKO97708.1 - 2e-86 289.4 0.8 2.4e-86 289.2 0.8 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 RKO97708.1 - 3.4e-28 97.8 0.1 1e-27 96.3 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pre-PUA PF17832.1 RKO97709.1 - 1.4e-25 89.8 0.2 2.6e-25 88.9 0.2 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 RKO97709.1 - 4.6e-20 71.3 0.1 7e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 PUA domain dCMP_cyt_deam_1 PF00383.23 RKO97710.1 - 2.7e-15 56.0 0.3 3.3e-15 55.8 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 RKO97710.1 - 1.4e-11 44.7 1.9 5.8e-11 42.7 0.2 2.0 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 RKO97710.1 - 0.0081 15.8 0.8 1.4 8.4 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases EI24 PF07264.11 RKO97712.1 - 1.2e-22 81.1 14.1 1.6e-22 80.6 14.1 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Radial_spoke PF04712.12 RKO97713.1 - 2.2e-11 43.4 0.0 4.4e-06 25.9 0.0 2.7 2 2 1 3 3 3 2 Radial spokehead-like protein FHA PF00498.26 RKO97714.1 - 3.8e-10 40.0 0.0 8.9e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain Adeno_knob PF00541.17 RKO97714.1 - 0.086 12.6 0.4 0.18 11.5 0.4 1.5 1 0 0 1 1 1 0 Adenoviral fibre protein (knob domain) FIT1_2 PF17357.2 RKO97714.1 - 0.27 11.3 8.0 2.2 8.4 1.6 2.5 2 0 0 2 2 2 0 Facilitor Of iron transport 1 and 2 2OG-FeII_Oxy_2 PF13532.6 RKO97715.1 - 5.9e-37 127.8 0.0 1.7e-36 126.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-C2H2_4 PF13894.6 RKO97717.1 - 2.4e-09 37.2 6.3 0.00012 22.6 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RKO97717.1 - 3.3e-09 36.7 7.0 4.7e-05 23.6 0.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 RKO97717.1 - 1.4e-05 25.0 1.0 0.025 14.6 0.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 RKO97717.1 - 0.0004 20.6 0.4 0.00047 20.4 0.4 1.1 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 RKO97717.1 - 0.0026 18.1 6.6 0.22 12.0 0.2 2.5 2 1 0 2 2 2 2 Zinc-finger double domain zf-LYAR PF08790.11 RKO97717.1 - 0.0035 17.2 1.1 0.11 12.5 0.3 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Zn-ribbon_8 PF09723.10 RKO97717.1 - 0.0044 17.1 2.7 0.96 9.6 0.2 2.1 2 0 0 2 2 2 2 Zinc ribbon domain Prok-RING_1 PF14446.6 RKO97717.1 - 0.0067 16.3 0.4 3.4 7.7 0.1 2.1 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 Lar_restr_allev PF14354.6 RKO97717.1 - 0.007 16.7 1.1 0.01 16.2 1.1 1.3 1 1 0 1 1 1 1 Restriction alleviation protein Lar zf-C2HC5 PF06221.13 RKO97717.1 - 0.0099 15.8 1.2 0.2 11.7 0.1 2.1 1 1 1 2 2 2 1 Putative zinc finger motif, C2HC5-type LIM PF00412.22 RKO97717.1 - 0.01 16.1 1.0 0.011 15.9 1.0 1.1 1 0 0 1 1 1 0 LIM domain Ribosomal_L35p PF01632.19 RKO97717.1 - 0.014 15.9 1.2 0.66 10.5 0.1 2.0 1 1 1 2 2 2 0 Ribosomal protein L35 zf_UBZ PF18439.1 RKO97717.1 - 0.014 15.0 1.0 3.4 7.3 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-FCS PF06467.14 RKO97717.1 - 0.015 15.2 1.1 2 8.4 0.2 2.1 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif HNH_5 PF14279.6 RKO97717.1 - 0.019 14.8 0.0 0.063 13.2 0.0 1.7 1 1 0 1 1 1 0 HNH endonuclease zf-ribbon_3 PF13248.6 RKO97717.1 - 0.019 14.3 0.7 0.84 9.1 0.1 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2HC_2 PF13913.6 RKO97717.1 - 0.036 14.0 5.9 1.3 9.0 0.3 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type TF_Zn_Ribbon PF08271.12 RKO97717.1 - 0.044 13.3 0.3 0.1 12.1 0.3 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding zf-C2H2_8 PF15909.5 RKO97717.1 - 0.046 14.0 0.7 0.051 13.9 0.7 1.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_3rep PF18868.1 RKO97717.1 - 0.053 14.2 0.2 0.071 13.8 0.2 1.3 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats Zn-C2H2_12 PF18112.1 RKO97717.1 - 0.058 13.9 0.6 1 9.9 0.2 2.7 2 1 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_2 PF12756.7 RKO97717.1 - 0.076 13.4 0.2 6.8 7.1 0.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) TFIIS_C PF01096.18 RKO97717.1 - 0.24 11.3 4.7 0.78 9.6 0.8 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-CHCC PF10276.9 RKO97717.1 - 0.32 11.1 4.2 1.7 8.8 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger domain DUF2256 PF10013.9 RKO97717.1 - 0.52 10.5 5.1 4.2 7.6 1.2 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Zn_Tnp_IS1595 PF12760.7 RKO97717.1 - 1 9.4 6.9 2.2 8.3 6.9 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Helicase_C_2 PF13307.6 RKO97718.1 - 1.6e-50 171.6 0.0 7.8e-50 169.4 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 RKO97718.1 - 1.2e-43 148.8 0.5 2.6e-43 147.7 0.5 1.5 1 1 0 1 1 1 1 DEAD_2 ResIII PF04851.15 RKO97718.1 - 6.6e-05 23.0 0.0 0.17 11.9 0.1 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 RKO97718.1 - 0.00066 19.5 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase HBB PF06777.11 RKO97718.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Helical and beta-bridge domain Baculo_F PF12259.8 RKO97718.1 - 0.028 13.0 0.1 0.04 12.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus F protein PhoH PF02562.16 RKO97718.1 - 0.044 13.2 0.0 7.5 5.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 RKO97718.1 - 0.057 12.1 0.4 0.33 9.6 0.4 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_19 PF13245.6 RKO97718.1 - 0.077 13.3 0.3 0.26 11.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain DNase-RNase PF02577.14 RKO97719.1 - 0.098 12.3 0.1 2.4 7.8 0.1 2.4 2 0 0 2 2 2 0 Bifunctional nuclease Homeodomain PF00046.29 RKO97720.1 - 1.7e-07 31.0 0.0 4e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Homeodomain zf_CCCH_4 PF18345.1 RKO97720.1 - 2e-05 24.5 8.2 3.1e-05 23.9 8.2 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 RKO97720.1 - 3.1e-05 23.8 3.4 5e-05 23.1 3.4 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 RKO97720.1 - 0.00032 20.4 6.0 0.00051 19.8 6.0 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger Med26 PF08711.11 RKO97720.1 - 0.0022 17.9 0.2 0.0054 16.7 0.1 1.7 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Torus PF16131.5 RKO97720.1 - 0.032 14.9 0.5 0.063 14.0 0.5 1.4 1 0 0 1 1 1 0 Torus domain FYDLN_acid PF09538.10 RKO97720.1 - 8.6 7.1 9.0 5.4 7.7 5.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) TRM13 PF05206.14 RKO97721.1 - 7.7e-63 212.5 0.0 1e-62 212.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-U11-48K PF05253.12 RKO97721.1 - 7.9e-07 28.9 0.2 7.9e-07 28.9 0.2 2.0 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 RKO97721.1 - 0.062 13.3 6.2 0.33 10.9 6.2 2.2 1 1 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 RKO97723.1 - 2.6e-42 144.4 0.0 3.3e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 RKO97723.1 - 2.3e-07 30.9 0.0 3.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_2 PF07724.14 RKO97723.1 - 4.4e-06 26.9 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 RKO97723.1 - 1e-05 25.5 0.0 3e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 RKO97723.1 - 2.2e-05 24.8 0.3 0.02 15.2 0.1 2.1 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.17 RKO97723.1 - 4.3e-05 23.3 0.0 5.7e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 RKO97723.1 - 5.4e-05 23.6 0.1 0.0004 20.8 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 RKO97723.1 - 0.00062 19.5 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 RKO97723.1 - 0.00065 19.1 0.0 0.00072 18.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.29 RKO97723.1 - 0.0012 18.7 0.1 0.18 11.6 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_7 PF12775.7 RKO97723.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_14 PF13173.6 RKO97723.1 - 0.0015 18.5 0.0 0.0021 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 RKO97723.1 - 0.0018 17.9 0.2 0.014 15.0 0.1 2.0 1 1 1 2 2 2 1 AAA domain SRP54 PF00448.22 RKO97723.1 - 0.0028 17.3 0.0 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain RNA_helicase PF00910.22 RKO97723.1 - 0.0032 17.8 0.0 0.0056 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 RKO97723.1 - 0.0033 17.2 0.0 0.01 15.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activat PF00158.26 RKO97723.1 - 0.0043 16.8 0.0 0.019 14.7 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 RKO97723.1 - 0.0044 16.4 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 RKO97723.1 - 0.012 15.4 0.0 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 RKO97723.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TIP49 PF06068.13 RKO97723.1 - 0.013 14.7 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_33 PF13671.6 RKO97723.1 - 0.021 15.0 0.0 0.035 14.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 RKO97723.1 - 0.029 13.8 0.0 5.3 6.4 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 RKO97723.1 - 0.037 14.6 0.0 0.046 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RKO97723.1 - 0.042 13.6 0.1 0.059 13.1 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 RKO97723.1 - 0.053 13.8 0.0 0.076 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RKO97723.1 - 0.063 12.6 0.1 0.22 10.9 0.1 1.7 1 1 0 1 1 1 0 KaiC Terminase_6 PF03237.15 RKO97723.1 - 0.073 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Terminase-like family AAA_19 PF13245.6 RKO97723.1 - 0.09 13.1 0.1 0.12 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 RKO97723.1 - 0.092 12.7 0.0 0.37 10.7 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_23 PF13476.6 RKO97723.1 - 0.1 13.1 0.0 0.13 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 RKO97723.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.18 RKO97723.1 - 0.22 11.3 0.0 0.27 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacterial dnaA protein PIF1 PF05970.14 RKO97723.1 - 0.23 10.6 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase ABC_membrane PF00664.23 RKO97724.1 - 1.9e-90 303.3 16.9 8e-46 156.9 4.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 RKO97724.1 - 2.5e-69 232.1 0.0 1.6e-33 116.1 0.0 2.8 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 RKO97724.1 - 4e-12 46.0 2.7 0.00018 21.0 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 RKO97724.1 - 2.5e-08 33.2 0.4 0.0034 16.3 0.0 2.8 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 RKO97724.1 - 9.4e-07 28.5 1.3 0.004 16.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 RKO97724.1 - 3.7e-06 27.3 1.8 0.012 15.9 0.1 3.6 3 1 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 RKO97724.1 - 1.1e-05 24.8 0.1 0.02 14.1 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_16 PF13191.6 RKO97724.1 - 7.7e-05 23.1 6.3 0.29 11.5 0.8 3.8 3 1 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 RKO97724.1 - 8.8e-05 22.5 0.3 0.33 10.9 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase AAA_30 PF13604.6 RKO97724.1 - 0.00011 22.0 3.1 0.64 9.7 0.0 3.9 3 2 0 3 3 3 2 AAA domain G-alpha PF00503.20 RKO97724.1 - 0.00048 19.4 0.1 0.66 9.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit SbcCD_C PF13558.6 RKO97724.1 - 0.001 19.3 0.5 1.4 9.2 0.2 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 RKO97724.1 - 0.0016 18.0 0.2 2.7 7.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 RKO97724.1 - 0.0019 18.1 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_15 PF13175.6 RKO97724.1 - 0.002 17.9 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 RKO97724.1 - 0.0029 16.8 0.0 0.57 9.3 0.0 2.5 3 0 0 3 3 2 1 Protein of unknown function (DUF815) DUF87 PF01935.17 RKO97724.1 - 0.0075 16.4 0.2 0.34 11.0 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_5 PF07728.14 RKO97724.1 - 0.0086 16.1 0.5 7.6 6.5 0.0 3.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) PRK PF00485.18 RKO97724.1 - 0.02 14.7 0.4 4.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 RKO97724.1 - 0.028 14.6 0.3 6.7 6.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.20 RKO97724.1 - 0.032 14.1 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 RKO97724.1 - 0.067 12.9 0.3 4.8 6.8 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 RKO97724.1 - 0.076 12.5 0.0 11 5.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 RKO97724.1 - 0.096 12.0 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 RKO97724.1 - 0.16 11.2 0.2 18 4.4 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 RKO97724.1 - 0.17 12.3 0.2 18 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 RKO97724.1 - 0.19 12.2 0.1 11 6.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 RKO97724.1 - 0.21 11.8 2.4 22 5.3 0.2 3.1 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.6 RKO97724.1 - 0.34 10.7 3.5 26 4.5 0.2 3.8 2 2 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Ly49 PF08391.10 RKO97725.1 - 0.00023 21.5 0.2 0.00046 20.5 0.2 1.4 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region Tup_N PF08581.10 RKO97725.1 - 0.075 13.3 4.1 0.13 12.6 4.1 1.2 1 0 0 1 1 1 0 Tup N-terminal ATG16 PF08614.11 RKO97725.1 - 0.11 12.7 7.3 0.18 12.0 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Ctr PF04145.15 RKO97725.1 - 0.12 13.0 0.3 16 6.1 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF2207 PF09972.9 RKO97726.1 - 0.1 11.4 0.3 0.15 10.8 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4307 PF14155.6 RKO97726.1 - 0.14 12.0 0.1 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) EF1G PF00647.19 RKO97727.1 - 2e-21 76.0 1.6 3.9e-21 75.1 1.6 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 RKO97727.1 - 3.3e-17 62.5 0.0 8e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 RKO97727.1 - 1.3e-13 51.1 0.0 2.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 RKO97727.1 - 1.8e-08 34.7 0.0 4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 RKO97727.1 - 2e-08 34.1 0.2 7.1e-08 32.4 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 RKO97727.1 - 1.2e-07 31.9 0.0 7.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 RKO97727.1 - 2.4e-05 24.6 0.0 5.4e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 RKO97727.1 - 0.023 15.1 0.0 0.049 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF866 PF05907.13 RKO97728.1 - 6.7e-41 139.8 0.0 7.4e-41 139.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Zn-C2H2_12 PF18112.1 RKO97728.1 - 0.13 12.7 1.3 0.24 11.9 0.3 1.9 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-H2C2_2 PF13465.6 RKO97728.1 - 0.25 11.9 1.2 20 5.9 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Cellulase PF00150.18 RKO97729.1 - 2.7e-16 59.9 0.0 2.9e-10 40.1 0.0 2.4 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 RKO97729.1 - 1.8e-07 31.6 0.0 3.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 RKO97729.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 SURF1 PF02104.15 RKO97730.1 - 9.4e-45 153.0 0.0 1.2e-44 152.7 0.0 1.0 1 0 0 1 1 1 1 SURF1 family Cyclin_N PF00134.23 RKO97733.1 - 2.9e-18 65.8 5.7 5.3e-16 58.5 2.8 2.7 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 RKO97733.1 - 0.00016 21.7 3.9 0.015 15.3 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat ExoD PF06055.12 RKO97733.1 - 0.12 11.8 0.6 0.39 10.1 0.0 1.9 1 1 1 2 2 2 0 Exopolysaccharide synthesis, ExoD Coilin_N PF15862.5 RKO97734.1 - 0.00084 19.2 0.0 0.0059 16.4 0.0 2.3 2 1 0 2 2 2 1 Coilin N-terminus RRM_1 PF00076.22 RKO97735.1 - 1.9e-47 159.0 1.0 1e-21 76.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 RKO97735.1 - 3.4e-07 30.0 0.0 0.012 15.4 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_3 PF08777.11 RKO97735.1 - 0.00016 21.6 0.0 4.5 7.4 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif RRM_7 PF16367.5 RKO97735.1 - 0.002 18.2 0.1 1.7 8.8 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RBM39linker PF15519.6 RKO97735.1 - 0.028 15.5 0.1 0.1 13.7 0.1 1.9 1 0 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein NDK PF00334.19 RKO97736.1 - 8.6e-23 80.8 0.0 5.3e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase Barwin PF00967.17 RKO97737.1 - 0.059 13.2 0.4 0.19 11.6 0.4 1.9 1 1 0 1 1 1 0 Barwin family SWI-SNF_Ssr4 PF08549.10 RKO97737.1 - 0.23 10.0 7.9 0.3 9.7 7.9 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Nop52 PF05997.12 RKO97738.1 - 1.4e-39 136.2 5.2 1.5e-39 136.0 5.2 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Ceramidase PF05875.12 RKO97739.1 - 2.5e-25 89.4 4.3 1.3e-14 54.3 1.9 2.0 1 1 1 2 2 2 2 Ceramidase UQ_con PF00179.26 RKO97740.1 - 1.6e-30 105.6 0.0 1.8e-30 105.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 RKO97740.1 - 3.6e-06 26.7 0.0 4.6e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 RKO97740.1 - 0.087 12.7 0.4 0.12 12.2 0.4 1.4 1 1 0 1 1 1 0 UEV domain HAD PF12710.7 RKO97743.1 - 8.7e-19 68.7 0.0 2.3e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 RKO97743.1 - 8e-16 59.0 0.3 1.9e-15 57.7 0.3 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ACT_6 PF13740.6 RKO97743.1 - 2e-09 37.3 2.5 6.5e-09 35.7 0.3 2.5 2 0 0 2 2 2 1 ACT domain Hydrolase_3 PF08282.12 RKO97743.1 - 2.5e-08 34.0 0.0 2.8e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 RKO97743.1 - 0.0036 17.4 0.1 3.9 7.5 0.0 3.1 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 RKO97743.1 - 0.0069 15.8 0.0 0.5 9.7 0.0 2.4 2 0 0 2 2 2 1 Putative Phosphatase DUF705 PF05152.12 RKO97743.1 - 0.015 14.8 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF705) SPX PF03105.19 RKO97743.1 - 0.06 13.3 0.0 0.094 12.6 0.0 1.2 1 0 0 1 1 1 0 SPX domain Ribosomal_S4e PF00900.20 RKO97744.1 - 2.9e-33 113.6 0.0 6.1e-33 112.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 RKO97744.1 - 1.2e-22 79.2 0.0 2e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 RKO97744.1 - 2.4e-18 66.0 10.3 4.4e-18 65.1 10.3 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 RKO97744.1 - 4.2e-06 26.4 0.0 8.5e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 RKO97744.1 - 3.4e-05 23.6 1.3 3.4e-05 23.6 1.3 2.1 2 0 0 2 2 2 1 KOW motif DUF3668 PF12416.8 RKO97745.1 - 0.004 17.0 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Cep120 protein C2 PF00168.30 RKO97745.1 - 0.065 13.5 0.0 0.3 11.4 0.0 2.1 3 0 0 3 3 3 0 C2 domain Pep_deformylase PF01327.21 RKO97746.1 - 2.4e-32 111.8 0.0 2.8e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase UBA PF00627.31 RKO97747.1 - 0.0055 16.6 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 RKO97747.1 - 0.21 11.6 0.1 1.4 8.9 0.1 2.0 2 0 0 2 2 2 0 HOIP UBA domain pair zf-CSL PF05207.13 RKO97748.1 - 2.7e-23 81.4 0.5 3.7e-23 81.0 0.5 1.2 1 0 0 1 1 1 1 CSL zinc finger zf-RING_7 PF02591.15 RKO97748.1 - 0.002 18.2 0.1 0.0037 17.4 0.1 1.5 1 0 0 1 1 1 1 C4-type zinc ribbon domain Prok-RING_1 PF14446.6 RKO97748.1 - 0.057 13.3 1.0 0.11 12.4 1.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 RNA_pol_Rpb1_5 PF04998.17 RKO97749.1 - 9.2e-102 340.0 0.0 1.5e-101 339.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 RKO97749.1 - 5.9e-100 334.6 0.1 9.5e-100 333.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 RKO97749.1 - 1.1e-71 240.4 0.0 2.2e-71 239.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 RKO97749.1 - 3.9e-65 219.3 0.0 1.1e-64 217.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 RKO97749.1 - 2.1e-46 157.7 0.0 8.2e-46 155.8 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 RKO97749.1 - 8e-39 131.9 0.2 1.9e-38 130.7 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 RKO97749.1 - 1.8e-36 125.1 1.6 3.3e-36 124.3 1.6 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.13 RKO97749.1 - 5.3e-08 32.8 326.0 0.43 11.0 16.3 15.8 9 2 14 23 23 23 20 RNA polymerase Rpb1 C-terminal repeat zf-C4pol PF14260.6 RKO97749.1 - 0.63 10.5 4.1 1.8 9.1 4.1 1.8 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Atg14 PF10186.9 RKO97750.1 - 1.7e-11 43.8 0.0 4.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 SF3b10 PF07189.11 RKO97751.1 - 1.7e-29 101.7 0.0 1.9e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) NIPSNAP PF07978.13 RKO97752.1 - 2.4e-40 136.9 3.2 9.9e-28 96.4 0.4 2.1 2 0 0 2 2 2 2 NIPSNAP Complex1_LYR_1 PF13232.6 RKO97753.1 - 0.0015 19.1 0.1 0.0027 18.3 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 RKO97753.1 - 0.042 13.9 0.2 0.11 12.5 0.2 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) HMA PF00403.26 RKO97754.1 - 9.7e-11 42.0 0.7 1.1e-10 41.7 0.7 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain SecY PF00344.20 RKO97756.1 - 1.3e-72 244.7 9.9 1.9e-72 244.1 9.9 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 RKO97756.1 - 8.5e-19 67.1 2.0 1.2e-18 66.6 0.2 2.3 2 0 0 2 2 2 1 Plug domain of Sec61p DEAD PF00270.29 RKO97757.1 - 6.6e-49 166.0 0.0 3.3e-48 163.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO97757.1 - 2.4e-32 111.5 0.0 6.7e-32 110.1 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO97757.1 - 0.0019 18.3 0.0 0.0088 16.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RKO97757.1 - 0.022 15.1 0.0 2.9 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain UTP25 PF06862.12 RKO97757.1 - 0.041 12.7 0.0 0.6 8.8 0.0 2.3 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 tRNA-synt_1 PF00133.22 RKO97758.1 - 3.3e-216 719.2 0.1 1.1e-215 717.5 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 RKO97758.1 - 9.1e-21 74.4 1.1 1.8e-20 73.4 0.1 2.0 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 RKO97758.1 - 1.4e-07 30.6 1.4 0.24 10.1 0.1 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) Rtt106 PF08512.12 RKO97759.1 - 1.5e-20 73.4 0.0 2.1e-19 69.7 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 RKO97759.1 - 2.8e-20 72.0 0.0 6.4e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 RKO97759.1 - 4e-15 56.0 0.0 1.2e-11 44.8 0.0 2.6 2 1 0 2 2 2 2 POB3-like N-terminal PH domain YL1 PF05764.13 RKO97759.1 - 1.2 9.2 7.2 1.7 8.7 7.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein TPR_19 PF14559.6 RKO97760.1 - 6.8e-07 29.7 15.2 0.014 15.9 0.0 6.1 4 2 2 6 6 6 3 Tetratricopeptide repeat C2 PF00168.30 RKO97760.1 - 0.00028 21.1 0.0 0.0021 18.3 0.0 2.2 2 0 0 2 2 2 1 C2 domain ANAPC3 PF12895.7 RKO97760.1 - 0.0023 18.1 8.7 0.14 12.4 1.4 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 RKO97760.1 - 0.0027 18.4 15.5 1.5 9.9 0.7 7.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKO97760.1 - 0.0028 17.6 11.2 0.76 10.0 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 RKO97760.1 - 0.01 16.2 2.9 0.34 11.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 RKO97760.1 - 0.081 12.8 2.6 22 5.1 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 RKO97760.1 - 0.085 13.0 6.6 3.3 7.9 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat PQ-loop PF04193.14 RKO97761.1 - 8.7e-33 111.9 6.6 1.8e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 RKO97761.1 - 0.0027 17.7 1.0 0.01 15.9 0.1 2.2 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange Ribosomal_L29 PF00831.23 RKO97762.1 - 9.2e-18 64.0 1.6 9.2e-18 64.0 1.6 1.7 2 1 0 2 2 2 1 Ribosomal L29 protein Snapin_Pallidin PF14712.6 RKO97762.1 - 0.00078 19.8 1.0 0.00078 19.8 1.0 1.5 2 0 0 2 2 2 1 Snapin/Pallidin Spc7 PF08317.11 RKO97762.1 - 0.058 12.3 1.1 0.079 11.8 1.2 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3860 PF12976.7 RKO97762.1 - 0.11 12.5 0.7 0.53 10.3 0.2 1.9 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) LPD15 PF18828.1 RKO97763.1 - 0.2 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Large polyvalent-protein-associated domain 15 WD40 PF00400.32 RKO97764.1 - 2.9e-46 154.5 25.8 1.4e-08 35.3 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97764.1 - 5.4e-12 45.8 1.9 0.19 12.0 0.0 4.9 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 RKO97764.1 - 3.2e-06 26.3 0.2 1.3 7.9 0.0 4.4 2 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 RKO97764.1 - 3.2e-05 22.8 9.8 0.045 12.4 0.2 4.7 4 1 2 6 6 6 2 Nucleoporin Nup120/160 eIF2A PF08662.11 RKO97764.1 - 0.00096 19.1 0.3 0.0051 16.7 0.1 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.11 RKO97764.1 - 0.0083 15.2 0.2 0.92 8.5 0.0 3.1 1 1 3 4 4 4 1 Protein of unknown function (DUF1513) bMG3 PF11974.8 RKO97764.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain IKI3 PF04762.12 RKO97764.1 - 0.13 10.2 0.0 1 7.3 0.0 2.2 2 1 1 3 3 3 0 IKI3 family WD40_like PF17005.5 RKO97764.1 - 0.22 10.8 0.0 6.9 5.9 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain Solute_trans_a PF03619.16 RKO97765.1 - 3.4e-70 236.6 15.3 3.9e-70 236.4 15.3 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 RKO97765.1 - 0.61 10.3 12.2 0.037 14.3 2.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Peptidase_M48 PF01435.18 RKO97766.1 - 5.3e-36 124.2 0.1 9.5e-36 123.4 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M48 DUF1356 PF07092.12 RKO97767.1 - 0.12 11.6 1.8 2.6 7.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) LEA_2 PF03168.13 RKO97767.1 - 0.22 12.1 0.5 4.8 7.8 0.5 2.6 1 1 0 1 1 1 0 Late embryogenesis abundant protein Cerato-platanin PF07249.12 RKO97768.1 - 0.00029 20.9 0.3 0.001 19.2 0.2 1.9 1 1 1 2 2 2 1 Cerato-platanin zf-C2H2_4 PF13894.6 RKO97769.1 - 4e-11 42.8 20.1 9.8e-05 22.9 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 RKO97769.1 - 4.9e-09 36.2 20.6 0.00022 21.5 2.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-TRAF PF02176.18 RKO97769.1 - 0.00021 21.9 0.6 0.00039 21.0 0.6 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger zf-Di19 PF05605.12 RKO97769.1 - 0.00087 19.5 0.8 0.00087 19.5 0.8 2.4 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 RKO97769.1 - 0.0015 18.5 15.4 0.016 15.2 0.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKO97769.1 - 0.0025 18.1 7.1 0.16 12.3 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 RKO97769.1 - 0.0085 16.5 0.4 0.0085 16.5 0.4 2.2 3 0 0 3 3 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 RKO97769.1 - 0.031 14.0 3.6 2.6 7.9 0.1 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 RKO97769.1 - 0.054 13.8 7.8 4.3 7.7 0.1 3.1 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.6 RKO97769.1 - 0.075 13.5 17.0 0.084 13.3 0.0 4.5 5 0 0 5 5 5 0 Zinc-finger double domain Zn-C2H2_12 PF18112.1 RKO97769.1 - 0.13 12.8 4.4 0.34 11.4 0.1 3.2 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 RKO97769.1 - 0.65 9.7 3.5 2.8 7.6 0.1 2.6 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-CSL PF05207.13 RKO97769.1 - 1.5 8.6 4.0 0.62 9.8 0.1 2.1 2 0 0 2 2 2 0 CSL zinc finger zf-C2H2_aberr PF17017.5 RKO97769.1 - 5 7.2 6.6 13 5.8 1.1 2.5 2 1 0 2 2 2 0 Aberrant zinc-finger ORMDL PF04061.14 RKO97771.1 - 8.3e-50 168.1 4.3 9.1e-50 168.0 4.3 1.0 1 0 0 1 1 1 1 ORMDL family HSP70 PF00012.20 RKO97774.1 - 1.2e-79 268.1 0.1 1.4e-79 267.9 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 RKO97774.1 - 2.4e-12 46.3 0.0 7.7e-12 44.7 0.0 1.7 2 1 0 2 2 2 1 MreB/Mbl protein Actin PF00022.19 RKO97774.1 - 0.12 10.9 0.0 13 4.3 0.0 2.5 3 0 0 3 3 3 0 Actin RNA_pol_N PF01194.17 RKO97775.1 - 1.2e-32 111.9 0.4 1.3e-32 111.8 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Sld5 PF05916.11 RKO97776.1 - 1.7e-08 34.9 0.0 2.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein TBP PF00352.21 RKO97777.1 - 1.6e-67 223.5 0.2 8.5e-33 112.2 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 RKO97777.1 - 4.7e-05 23.4 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 RKO97777.1 - 0.12 12.1 0.1 0.49 10.3 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Lsr2 PF11774.8 RKO97778.1 - 3.2 7.9 7.0 30 4.8 7.0 2.0 1 1 0 1 1 1 0 Lsr2 Hexokinase_2 PF03727.16 RKO97779.1 - 1.8e-81 273.1 0.0 2.7e-81 272.5 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 RKO97779.1 - 6.5e-69 231.8 0.0 8.9e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Lyase_1 PF00206.20 RKO97780.1 - 9.8e-123 409.5 0.0 1.3e-122 409.1 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 RKO97780.1 - 7e-25 87.2 1.4 1.9e-24 85.8 0.5 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus TB2_DP1_HVA22 PF03134.19 RKO97781.1 - 2.1e-29 101.3 3.8 2.1e-29 101.3 3.8 2.0 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 RKO97781.1 - 0.079 13.2 3.7 2.8 8.2 0.3 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2516 PF10724.9 RKO97781.1 - 0.29 11.5 5.4 0.59 10.5 5.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2516) MutS_V PF00488.21 RKO97782.1 - 1.2e-38 133.1 0.0 3.9e-38 131.4 0.0 1.8 1 1 0 1 1 1 1 MutS domain V AAA_29 PF13555.6 RKO97782.1 - 0.028 14.1 0.1 0.099 12.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MutS_III PF05192.18 RKO97782.1 - 0.05 13.8 0.3 0.081 13.1 0.3 1.3 1 0 0 1 1 1 0 MutS domain III NigD_N PF12667.7 RKO97783.1 - 0.0038 17.3 0.2 1.6 8.9 0.5 2.6 2 0 0 2 2 2 2 NigD-like N-terminal OB domain Mucin PF01456.17 RKO97784.1 - 0.01 15.9 38.7 0.01 15.9 38.7 4.3 3 1 0 3 3 3 0 Mucin-like glycoprotein Nop14 PF04147.12 RKO97784.1 - 0.033 12.4 15.9 0.045 12.0 15.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 RKO97784.1 - 0.042 13.2 16.7 0.073 12.4 16.7 1.3 1 0 0 1 1 1 0 BUD22 Integrin_b_cyt PF08725.11 RKO97784.1 - 0.075 12.7 2.6 0.62 9.8 0.2 2.8 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain SDA1 PF05285.12 RKO97784.1 - 0.12 11.7 14.2 0.17 11.3 14.2 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 RKO97784.1 - 1 7.6 9.3 1.6 6.9 9.3 1.3 1 0 0 1 1 1 0 CDC45-like protein TPR_19 PF14559.6 RKO97785.1 - 1e-08 35.5 7.0 5e-05 23.7 0.3 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 RKO97785.1 - 2.4e-06 27.2 2.0 1.1 9.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 RKO97785.1 - 1.5e-05 25.0 5.9 0.0016 18.6 4.2 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_MalT PF17874.1 RKO97785.1 - 2e-05 24.2 4.2 2.9e-05 23.6 4.2 1.3 1 1 0 1 1 1 1 MalT-like TPR region TPR_8 PF13181.6 RKO97785.1 - 9.9e-05 22.3 1.3 1.6 9.1 0.0 4.7 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 RKO97785.1 - 0.00024 21.3 1.0 5.4 7.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 RKO97785.1 - 0.00031 21.3 6.8 0.0037 17.9 0.5 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 RKO97785.1 - 0.00075 20.1 7.4 0.18 12.7 0.2 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 RKO97785.1 - 0.00097 19.4 6.2 0.084 13.2 1.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 RKO97785.1 - 0.0015 18.4 1.7 1.1 9.4 0.0 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 RKO97785.1 - 0.0024 18.4 2.1 22 6.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO97785.1 - 0.009 16.2 2.1 4.5 7.6 0.3 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 RKO97785.1 - 0.012 15.4 0.6 4.4 7.3 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 RKO97785.1 - 0.14 12.5 1.7 14 6.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 RKO97785.1 - 0.32 11.8 13.0 0.28 11.9 1.5 3.3 3 1 0 3 3 2 0 Tetratricopeptide repeat E1-E2_ATPase PF00122.20 RKO97786.1 - 7.4e-45 152.7 0.2 1.9e-44 151.4 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 RKO97786.1 - 1.5e-15 58.0 0.7 2e-08 34.8 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 RKO97786.1 - 6.8e-15 54.9 0.0 1.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 RKO97786.1 - 1.3e-13 51.1 23.1 1.9e-12 47.3 7.4 3.1 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 RKO97786.1 - 2.1e-05 24.1 0.0 4.8e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKO97786.1 - 0.0025 17.6 2.0 0.04 13.7 1.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LIM PF00412.22 RKO97787.1 - 1.8e-31 108.2 29.9 2.1e-12 47.0 3.6 3.2 3 0 0 3 3 3 3 LIM domain zf-ribbon_3 PF13248.6 RKO97787.1 - 0.00072 18.9 3.8 0.9 9.0 0.0 4.7 4 0 0 4 4 4 2 zinc-ribbon domain DZR PF12773.7 RKO97787.1 - 0.0031 17.5 24.4 3.3 7.8 1.0 4.7 1 1 1 2 2 2 1 Double zinc ribbon zf-B_box PF00643.24 RKO97787.1 - 0.058 13.6 1.1 0.058 13.6 1.1 5.7 6 2 1 7 7 7 0 B-box zinc finger zf_UBZ PF18439.1 RKO97787.1 - 0.084 12.5 0.6 0.084 12.5 0.6 5.6 7 0 0 7 7 7 0 Ubiquitin-Binding Zinc Finger YsaB PF13983.6 RKO97787.1 - 0.26 11.6 2.4 18 5.7 0.2 2.6 2 0 0 2 2 2 0 YsaB-like lipoprotein FUR PF01475.19 RKO97787.1 - 0.43 10.7 1.6 26 5.0 0.1 2.4 2 0 0 2 2 2 0 Ferric uptake regulator family LRR_4 PF12799.7 RKO97788.1 - 1.2e-17 63.7 10.9 5.6e-07 29.8 2.1 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 RKO97788.1 - 4.2e-11 42.4 7.4 0.0021 17.8 0.0 4.0 3 1 1 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 RKO97788.1 - 6e-09 35.6 1.5 5.4e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 RKO97788.1 - 0.0065 16.9 6.3 12 6.9 0.2 4.6 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 RKO97788.1 - 0.076 13.1 1.9 24 5.3 0.3 4.0 4 0 0 4 4 4 0 Leucine Rich repeat FNIP PF05725.12 RKO97788.1 - 0.077 13.2 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 FNIP Repeat Thioredoxin PF00085.20 RKO97789.1 - 3.6e-06 26.9 0.1 5e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.16 RKO97789.1 - 0.016 15.0 1.0 0.021 14.6 1.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 RNA_pol_Rpb2_6 PF00562.28 RKO97790.1 - 5.6e-111 371.4 0.0 1.4e-110 370.0 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 RKO97790.1 - 3.2e-35 121.5 0.0 5.1e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 RKO97790.1 - 4.8e-28 97.1 0.1 1.2e-27 95.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 RKO97790.1 - 2.2e-19 69.8 0.0 3.9e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 RKO97790.1 - 4.7e-19 68.2 0.0 1.7e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 RKO97790.1 - 0.0026 18.1 0.4 0.0096 16.3 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 GSIII_N PF12437.8 RKO97791.1 - 1.6e-66 222.9 0.2 5.4e-66 221.2 0.1 1.9 2 0 0 2 2 2 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 RKO97791.1 - 2.2e-37 127.5 0.0 3.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 RKO97791.1 - 8.5e-22 77.6 0.0 1.7e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Phage_GPL PF05926.11 RKO97791.1 - 0.022 14.8 0.2 0.081 12.9 0.2 1.9 1 0 0 1 1 1 0 Phage head completion protein (GPL) TetR_C_33 PF13305.6 RKO97791.1 - 0.052 14.3 0.2 3.7 8.3 0.1 2.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain IQ PF00612.27 RKO97792.1 - 0.0085 15.8 0.6 0.1 12.5 0.3 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif BLI1 PF17324.2 RKO97792.1 - 0.018 15.7 3.0 0.018 15.7 3.0 2.6 2 1 0 2 2 2 0 BLOC-1 interactor 1 Noelin-1 PF12308.8 RKO97792.1 - 0.038 14.0 1.2 0.038 14.0 1.2 3.0 2 1 1 3 3 3 0 Neurogenesis glycoprotein DUF5481 PF17578.2 RKO97792.1 - 0.11 12.9 0.7 1 9.8 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5481) Nucleoporin_C PF03177.14 RKO97793.1 - 3.8e-36 125.0 0.0 7.3e-36 124.1 0.0 1.4 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal LIM PF00412.22 RKO97794.1 - 2.7e-26 91.5 35.2 7.1e-13 48.6 3.1 5.1 4 1 0 4 4 4 4 LIM domain BAG6 PF12057.8 RKO97794.1 - 0.27 10.9 1.5 0.57 9.9 0.9 1.8 2 0 0 2 2 2 0 BCL2-associated athanogene 6 DUF1840 PF08895.11 RKO97794.1 - 1.3 9.4 4.4 2.5 8.4 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1840) Rhodanese PF00581.20 RKO97795.1 - 4.3e-08 33.6 0.0 5.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ebp2 PF05890.12 RKO97796.1 - 3.6e-56 190.7 11.6 3.9e-56 190.6 11.6 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Phage_Mu_F PF04233.14 RKO97796.1 - 0.17 12.6 2.1 0.35 11.6 1.7 1.6 1 1 0 1 1 1 0 Phage Mu protein F like protein LETM1 PF07766.13 RKO97797.1 - 0.00033 20.1 0.1 0.00052 19.4 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein DEAD PF00270.29 RKO97798.1 - 1.7e-35 122.4 0.3 3.2e-35 121.5 0.3 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO97798.1 - 2.3e-25 89.1 0.2 5.3e-25 87.9 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO97798.1 - 1.3e-05 25.2 0.0 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 RKO97798.1 - 0.0026 17.5 0.1 0.0051 16.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 RKO97798.1 - 0.24 11.6 1.0 1.8 8.8 1.0 2.5 2 1 0 2 2 2 0 AAA domain C2 PF00168.30 RKO97799.1 - 2.1e-18 66.5 0.0 2.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 C2 domain CEP76-C2 PF15627.6 RKO97799.1 - 0.021 14.4 0.0 0.31 10.6 0.0 2.0 1 1 1 2 2 2 0 CEP76 C2 domain LIM PF00412.22 RKO97800.1 - 6.3e-43 144.8 35.0 1.7e-13 50.5 4.4 4.5 4 1 0 4 4 4 4 LIM domain KH_1 PF00013.29 RKO97801.1 - 1.5e-51 172.1 9.2 2.4e-17 62.5 0.5 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 RKO97801.1 - 4e-16 58.6 1.7 0.00051 19.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 RKO97801.1 - 3.8e-11 42.7 0.6 0.00087 19.1 0.0 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 RKO97801.1 - 0.0027 17.7 0.0 0.59 10.2 0.0 2.9 3 0 0 3 3 3 1 KH-like RNA-binding domain SLS PF14611.6 RKO97801.1 - 0.055 13.3 0.0 2.5 7.9 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.6 RKO97801.1 - 0.15 12.2 4.5 7.5 6.7 0.0 3.1 3 0 0 3 3 3 0 NusA-like KH domain Thiolase_N PF00108.23 RKO97802.1 - 2.9e-83 279.2 0.0 4e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RKO97802.1 - 1.2e-32 112.2 5.5 5.3e-32 110.1 4.1 2.6 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RKO97802.1 - 3.5e-05 23.5 1.5 7.1e-05 22.5 1.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAPS PF04499.15 RKO97803.1 - 3.3e-84 283.4 0.0 9.1e-50 169.8 0.0 2.2 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein B-block_TFIIIC PF04182.12 RKO97804.1 - 2.4e-11 43.6 0.1 8.8e-11 41.8 0.0 2.1 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC HTH_24 PF13412.6 RKO97804.1 - 6.4e-06 25.6 0.0 0.071 12.7 0.0 2.8 2 0 0 2 2 2 2 Winged helix-turn-helix DNA-binding MarR PF01047.22 RKO97804.1 - 0.12 12.3 0.0 9.1 6.3 0.0 3.3 3 0 0 3 3 3 0 MarR family Glyco_transf_20 PF00982.21 RKO97805.1 - 2.7e-157 524.3 0.0 3.5e-157 523.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 RKO97805.1 - 6.1e-30 104.1 0.0 1.2e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase PCI PF01399.27 RKO97806.1 - 6.8e-14 52.3 0.0 1.4e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF4810 PF16068.5 RKO97806.1 - 0.11 13.0 0.0 0.59 10.7 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) F-box-like PF12937.7 RKO97807.1 - 0.063 13.2 0.2 2.1 8.3 0.3 3.1 3 0 0 3 3 3 0 F-box-like SIL1 PF16782.5 RKO97808.1 - 0.0032 16.7 0.0 0.0044 16.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 HEAT_2 PF13646.6 RKO97808.1 - 0.0098 16.3 0.1 7.7 7.0 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats PUL PF08324.11 RKO97808.1 - 0.087 12.0 0.0 0.21 10.8 0.0 1.4 1 1 0 1 1 1 0 PUL domain Cerato-platanin PF07249.12 RKO97810.1 - 0.0038 17.3 0.1 0.0083 16.2 0.1 1.6 1 0 0 1 1 1 1 Cerato-platanin Mito_carr PF00153.27 RKO97811.1 - 4.3e-51 170.8 2.1 1.4e-21 76.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ALG11_N PF15924.5 RKO97812.1 - 2.4e-51 174.8 0.5 3.7e-51 174.2 0.5 1.3 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 RKO97812.1 - 3.4e-17 62.5 0.0 4.8e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 RKO97812.1 - 2.8e-13 50.4 0.4 4.5e-13 49.8 0.4 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 RKO97812.1 - 0.0042 17.5 3.4 0.0057 17.0 0.0 2.7 2 1 1 3 3 3 1 Glycosyl transferases group 1 PALP PF00291.25 RKO97813.1 - 6e-62 209.7 0.1 1.3e-61 208.6 0.1 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PTR2 PF00854.21 RKO97814.1 - 4.6e-74 249.6 0.1 6.9e-74 249.0 0.1 1.2 1 0 0 1 1 1 1 POT family DUF3561 PF12084.8 RKO97814.1 - 5.8 7.0 8.9 6.6 6.8 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3561) EmrE PF13536.6 RKO97815.1 - 0.071 12.7 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative multidrug resistance efflux transporter Fz PF01392.22 RKO97815.1 - 0.9 10.2 16.4 0.088 13.4 10.4 2.2 1 1 1 2 2 2 0 Fz domain CAP PF00188.26 RKO97816.1 - 4.5e-11 43.7 3.9 5.5e-11 43.4 3.9 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TFIIS_M PF07500.14 RKO97817.1 - 7.3e-12 45.8 0.0 1.9e-11 44.4 0.0 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 RKO97817.1 - 5.5e-10 39.0 8.4 9.3e-10 38.3 8.4 1.4 1 0 0 1 1 1 1 PHD-finger Terminase_GpA PF05876.12 RKO97817.1 - 0.0012 17.4 0.2 0.0018 16.9 0.2 1.1 1 0 0 1 1 1 1 Phage terminase large subunit (GpA) Defensin_4 PF07936.12 RKO97817.1 - 0.02 14.8 0.1 0.048 13.5 0.1 1.6 1 0 0 1 1 1 0 Potassium-channel blocking toxin P_proprotein PF01483.20 RKO97818.1 - 1.2e-21 76.5 0.2 1.2e-21 76.5 0.2 1.6 2 0 0 2 2 2 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 RKO97818.1 - 1.7e-12 47.2 0.3 2e-12 47.0 0.3 1.1 1 0 0 1 1 1 1 Subtilase family Ribosomal_L14 PF00238.19 RKO97820.1 - 4e-44 149.6 1.2 4.4e-44 149.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e CS PF04969.16 RKO97821.1 - 2.3e-19 70.2 0.4 5e-19 69.1 0.1 1.7 2 0 0 2 2 2 1 CS domain PAP2 PF01569.21 RKO97822.1 - 3.1e-27 95.0 4.4 3.1e-27 95.0 4.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 RKO97822.1 - 0.0088 16.6 0.7 0.0088 16.6 0.7 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal DUF805 PF05656.14 RKO97822.1 - 0.024 15.0 8.1 0.29 11.6 1.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF805) PAP2_3 PF14378.6 RKO97822.1 - 3.2 7.4 15.4 1.5 8.5 9.9 2.7 2 1 0 2 2 2 0 PAP2 superfamily zf-Tim10_DDP PF02953.15 RKO97823.1 - 1.7e-17 62.8 2.1 2.1e-17 62.5 2.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 RKO97823.1 - 0.014 15.1 1.0 0.017 14.8 1.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) E1-E2_ATPase PF00122.20 RKO97824.1 - 4.8e-43 146.8 1.6 2.4e-42 144.5 0.5 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 RKO97824.1 - 8.7e-21 74.4 11.2 2.8e-15 56.5 0.7 3.2 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 RKO97824.1 - 3.9e-20 71.7 0.0 8.2e-20 70.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 RKO97824.1 - 1.3e-18 68.1 0.0 1.3e-16 61.6 0.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RKO97824.1 - 6e-09 35.5 0.0 1.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKO97824.1 - 0.00036 20.4 0.5 0.043 13.5 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pox_A14 PF05767.12 RKO97824.1 - 0.037 14.2 1.4 0.083 13.1 0.1 2.3 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 HIG_1_N PF04588.13 RKO97824.1 - 0.55 10.5 4.0 3.3 8.0 0.0 3.3 3 0 0 3 3 3 0 Hypoxia induced protein conserved region DER1 PF04511.15 RKO97825.1 - 1.1e-55 188.6 2.4 1.2e-55 188.4 2.4 1.0 1 0 0 1 1 1 1 Der1-like family ADK PF00406.22 RKO97826.1 - 2.5e-59 199.7 0.0 2.9e-59 199.5 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RKO97826.1 - 5.5e-21 75.4 0.2 1.8e-20 73.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain ADK_lid PF05191.14 RKO97826.1 - 1.6e-16 59.9 0.0 4.3e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.6 RKO97826.1 - 0.00027 21.1 0.0 0.00053 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 RKO97826.1 - 0.0069 16.9 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 RKO97826.1 - 0.088 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain PWI PF01480.17 RKO97827.1 - 1.2e-14 54.4 0.0 1.6e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 PWI domain RCC1 PF00415.18 RKO97829.1 - 9.2e-18 64.6 6.7 7.6e-05 23.3 0.0 6.7 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 RKO97829.1 - 1e-12 47.5 31.9 0.00011 21.8 0.7 6.9 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Thiolase_N PF00108.23 RKO97830.1 - 3.7e-89 298.5 3.0 5e-89 298.1 3.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 RKO97830.1 - 9e-42 141.6 2.0 1.9e-41 140.5 0.8 2.1 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 RKO97830.1 - 0.00014 21.5 2.2 0.0062 16.1 1.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 RKO97830.1 - 0.056 13.6 0.1 2.7 8.2 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Aconitase PF00330.20 RKO97831.1 - 2e-102 343.6 0.7 2.8e-101 339.8 0.7 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 RKO97831.1 - 4.9e-19 68.9 0.0 9.8e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Formyl_trans_N PF00551.19 RKO97832.1 - 7.9e-22 77.9 0.1 8.5e-22 77.8 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase DUF1640 PF07798.11 RKO97833.1 - 2.1e-34 119.1 6.0 2.4e-34 118.9 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TPR_MLP1_2 PF07926.12 RKO97833.1 - 8.7e-05 22.6 3.1 0.0006 19.9 0.3 2.1 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.12 RKO97833.1 - 0.00023 21.2 3.8 0.11 12.5 0.2 2.2 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Prominin PF05478.11 RKO97833.1 - 0.0025 15.9 1.5 0.0028 15.7 1.5 1.0 1 0 0 1 1 1 1 Prominin LppA PF16708.5 RKO97833.1 - 0.0026 17.7 0.9 0.66 9.9 0.0 2.6 1 1 2 3 3 3 1 Lipoprotein confined to pathogenic Mycobacterium Apolipoprotein PF01442.18 RKO97833.1 - 0.0067 16.3 8.6 0.015 15.2 8.6 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain CPSF73-100_C PF11718.8 RKO97833.1 - 0.013 15.1 0.6 0.12 11.9 0.1 2.0 1 1 1 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Es2 PF09751.9 RKO97833.1 - 0.021 14.6 1.6 0.025 14.4 1.6 1.1 1 0 0 1 1 1 0 Nuclear protein Es2 Exonuc_VII_L PF02601.15 RKO97833.1 - 0.022 14.4 1.7 0.028 14.0 1.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ApoLp-III PF07464.11 RKO97833.1 - 0.026 14.6 0.8 0.11 12.6 0.8 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF3958 PF13125.6 RKO97833.1 - 0.05 13.8 8.3 0.32 11.2 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3958) HetR_C PF18460.1 RKO97833.1 - 0.057 13.4 1.2 0.17 11.9 0.7 2.0 1 1 1 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain COG2 PF06148.11 RKO97833.1 - 0.067 13.3 6.1 2.7 8.1 2.4 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lectin_N PF03954.14 RKO97833.1 - 0.076 12.8 0.8 0.2 11.4 0.7 1.7 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Oxygenase-NA PF09859.9 RKO97833.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA adh_short PF00106.25 RKO97833.1 - 0.1 12.0 0.1 0.24 10.8 0.1 1.5 1 1 0 2 2 2 0 short chain dehydrogenase CdvA PF18822.1 RKO97833.1 - 0.14 12.0 6.3 0.22 11.4 1.0 2.7 1 1 2 3 3 3 0 CdvA-like coiled-coil domain DUF1451 PF07295.11 RKO97833.1 - 0.16 12.0 3.3 0.55 10.3 2.0 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain DUF1664 PF07889.12 RKO97833.1 - 0.17 11.9 5.2 0.84 9.7 2.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF883 PF05957.13 RKO97833.1 - 0.18 12.4 7.5 3.8 8.2 0.5 2.7 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) DivIC PF04977.15 RKO97833.1 - 0.45 10.3 8.6 0.096 12.5 1.9 2.6 2 2 1 3 3 3 0 Septum formation initiator HSCB_C PF07743.13 RKO97833.1 - 0.47 11.0 8.9 0.46 11.0 0.6 2.7 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Fzo_mitofusin PF04799.13 RKO97833.1 - 0.6 9.7 3.9 0.86 9.1 0.8 2.1 1 1 1 2 2 2 0 fzo-like conserved region DUF3450 PF11932.8 RKO97833.1 - 0.73 9.1 9.1 6.2 6.0 9.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) XhlA PF10779.9 RKO97833.1 - 1.5 9.1 6.7 9.1 6.6 0.4 2.6 2 1 0 2 2 2 0 Haemolysin XhlA FlaC_arch PF05377.11 RKO97833.1 - 2.1 8.8 8.4 14 6.2 0.3 3.3 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) CorA PF01544.18 RKO97833.1 - 3.1 7.0 10.5 6.8 5.9 1.2 1.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein HalX PF08663.10 RKO97833.1 - 6 7.3 12.6 19 5.7 2.0 3.8 2 2 0 2 2 2 0 HalX domain NIF PF03031.18 RKO97834.1 - 9.8e-56 187.9 0.1 1.2e-55 187.6 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Rad51 PF08423.11 RKO97835.1 - 5.8e-23 81.5 0.0 3.2e-11 43.0 0.0 2.4 1 1 1 2 2 2 2 Rad51 AAA_25 PF13481.6 RKO97835.1 - 0.00062 19.4 0.5 0.3 10.6 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 RKO97835.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RKO97835.1 - 0.14 12.4 0.0 0.81 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 RKO97835.1 - 0.19 12.3 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 RKO97835.1 - 0.2 11.0 0.0 0.46 9.8 0.0 1.6 1 0 0 1 1 1 0 KaiC Herpes_gI PF01688.17 RKO97836.1 - 0.16 11.8 1.8 0.31 11.0 1.8 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Aminotran_1_2 PF00155.21 RKO97837.1 - 9.2e-13 48.1 0.0 1.8e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Cwf_Cwc_15 PF04889.12 RKO97839.1 - 0.23 11.2 2.4 0.42 10.3 2.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 RKO97839.1 - 0.27 11.1 0.3 0.52 10.2 0.3 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region 2-oxoacid_dh PF00198.23 RKO97840.1 - 2.5e-79 266.0 2.1 2.8e-79 265.8 2.1 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Histone PF00125.24 RKO97841.1 - 3.9e-22 79.0 0.1 4.8e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RKO97841.1 - 9.7e-07 29.0 0.0 1.7e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 RKO97841.1 - 0.0038 17.7 0.0 0.0063 17.0 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 RKO97841.1 - 0.02 15.1 0.0 0.029 14.6 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein DUF2514 PF10721.9 RKO97841.1 - 0.07 13.2 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) YscO-like PF16789.5 RKO97841.1 - 0.14 12.1 0.0 0.16 12.0 0.0 1.1 1 0 0 1 1 1 0 YscO-like protein Histone_H2A_C PF16211.5 RKO97842.1 - 3.8e-18 64.9 1.2 7.8e-18 63.9 1.2 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 RKO97842.1 - 1.7e-15 57.5 0.0 2.2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 RKO97842.1 - 3.3e-05 24.1 0.0 4.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone STE PF02200.16 RKO97844.1 - 1.4e-39 134.9 0.0 1.7e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 STE like transcription factor Cg6151-P PF10233.9 RKO97847.1 - 2.3e-25 89.1 13.6 2.8e-25 88.8 13.6 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P Phage_holin_3_6 PF07332.11 RKO97847.1 - 0.23 11.5 0.2 0.23 11.5 0.2 2.5 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III PRA1 PF03208.19 RKO97847.1 - 1.2 8.8 12.4 2.9 7.5 12.4 1.6 1 1 0 1 1 1 0 PRA1 family protein Ac76 PF05814.11 RKO97847.1 - 4.9 7.2 9.6 0.38 10.8 0.3 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) Cyt_b-c1_8 PF10890.8 RKO97849.1 - 0.059 13.8 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 IDEAL PF08858.10 RKO97849.1 - 0.19 11.5 0.1 0.64 9.8 0.1 1.9 1 0 0 1 1 1 0 IDEAL domain DUF515 PF04415.12 RKO97851.1 - 0.0061 15.0 6.1 0.023 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF515) TMEM154 PF15102.6 RKO97851.1 - 0.075 12.9 11.8 4 7.3 11.8 2.2 1 1 0 1 1 1 0 TMEM154 protein family Plasmodium_Vir PF05795.11 RKO97851.1 - 0.35 10.2 1.4 0.49 9.8 1.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SPX PF03105.19 RKO97851.1 - 0.88 9.4 8.2 1.1 9.1 8.2 1.1 1 0 0 1 1 1 0 SPX domain Mid2 PF04478.12 RKO97851.1 - 9.3 6.1 9.6 0.26 11.1 0.5 2.6 1 1 2 3 3 3 0 Mid2 like cell wall stress sensor Glyco_hydro_77 PF02446.17 RKO97852.1 - 1.7e-150 501.9 0.0 2.4e-150 501.5 0.0 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase SH3_9 PF14604.6 RKO97854.1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO97854.1 - 2.7e-09 36.5 0.0 4.5e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain Orf78 PF06024.12 RKO97854.1 - 0.013 15.8 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 Orf78 (ac78) FeoB_associated PF12669.7 RKO97854.1 - 0.017 15.5 2.4 0.017 15.5 2.4 2.2 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein RCR PF12273.8 RKO97854.1 - 0.034 14.8 0.1 0.093 13.4 0.0 1.7 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF1180 PF06679.12 RKO97854.1 - 0.041 14.3 0.1 0.041 14.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ODV-E18 PF10717.9 RKO97854.1 - 0.059 13.2 0.3 0.18 11.7 0.3 1.8 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.6 RKO97854.1 - 0.1 13.5 0.0 0.2 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ECSCR PF15820.5 RKO97854.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator DUF4577 PF15145.6 RKO97854.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) Prefoldin PF02996.17 RKO97856.1 - 6e-30 103.6 1.6 8.2e-30 103.2 1.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit AAA_13 PF13166.6 RKO97856.1 - 0.00099 17.9 0.9 0.0012 17.6 0.9 1.0 1 0 0 1 1 1 1 AAA domain Prefoldin_2 PF01920.20 RKO97856.1 - 0.0015 18.5 3.4 0.045 13.7 0.2 2.2 2 0 0 2 2 2 2 Prefoldin subunit Phage_GP20 PF06810.11 RKO97856.1 - 0.003 17.4 3.5 0.44 10.4 0.1 2.1 2 0 0 2 2 2 2 Phage minor structural protein GP20 End3 PF12761.7 RKO97856.1 - 0.0067 16.6 1.6 0.02 15.1 0.2 2.0 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 L31 PF09784.9 RKO97856.1 - 0.011 16.1 0.7 0.47 10.9 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Noelin-1 PF12308.8 RKO97856.1 - 0.02 14.8 0.6 3.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein Syntaxin-6_N PF09177.11 RKO97856.1 - 0.028 15.0 4.5 0.35 11.4 1.1 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal LMP PF04778.12 RKO97856.1 - 0.056 13.4 0.8 1.8 8.5 0.1 2.2 2 0 0 2 2 2 0 LMP repeated region DUF5082 PF16888.5 RKO97856.1 - 0.078 13.3 1.6 4.5 7.6 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) CLZ PF16526.5 RKO97856.1 - 1.5 9.3 4.9 21 5.6 0.4 2.5 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Myb_DNA-binding PF00249.31 RKO97857.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Macoilin PF09726.9 RKO97857.1 - 6.6 5.2 10.6 15 4.0 10.6 1.6 1 0 0 1 1 1 0 Macoilin family NIF PF03031.18 RKO97858.1 - 3.4e-55 186.1 0.1 4.1e-55 185.8 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WzyE PF06899.11 RKO97858.1 - 0.23 10.4 0.0 0.31 9.9 0.0 1.1 1 0 0 1 1 1 0 WzyE protein, O-antigen assembly polymerase SPX PF03105.19 RKO97859.1 - 7.3 6.4 5.8 8.6 6.2 5.8 1.1 1 0 0 1 1 1 0 SPX domain TP_methylase PF00590.20 RKO97860.1 - 4.6e-24 85.5 0.0 7.8e-24 84.8 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Pam16 PF03656.13 RKO97861.1 - 6.3e-21 74.7 1.5 9.2e-21 74.2 1.5 1.2 1 0 0 1 1 1 1 Pam16 Sec6 PF06046.13 RKO97861.1 - 0.09 11.1 0.0 0.1 10.9 0.0 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec6 Ribosomal_60s PF00428.19 RKO97861.1 - 4.9 7.8 12.7 10 6.8 4.5 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein UQ_con PF00179.26 RKO97862.1 - 1.3e-50 170.7 0.0 1.4e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 RKO97862.1 - 0.0049 17.1 0.0 0.0097 16.2 0.0 1.6 2 0 0 2 2 2 1 RWD domain Prok-E2_B PF14461.6 RKO97862.1 - 0.019 14.7 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 RKO97862.1 - 0.047 13.6 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF2420 PF10336.9 RKO97863.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) RPA43_OB PF17875.1 RKO97865.1 - 2.2e-10 41.2 0.0 2.2e-10 41.2 0.0 4.5 2 2 1 3 3 3 1 RPA43 OB domain in RNA Pol I Citrate_bind PF16114.5 RKO97866.1 - 1.7e-85 285.0 0.0 3.2e-85 284.1 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 RKO97866.1 - 1e-19 70.9 0.2 4.8e-18 65.4 0.1 2.6 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 RKO97866.1 - 1.1e-12 48.4 0.0 3e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.19 RKO97866.1 - 1.4e-11 44.4 0.1 4.3e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_2 PF08442.10 RKO97866.1 - 8.1e-07 28.8 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.6 RKO97866.1 - 9.6e-06 25.4 0.0 0.0001 22.1 0.0 2.4 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Reovirus_M2 PF05993.12 RKO97866.1 - 0.019 13.1 0.1 0.11 10.6 0.0 1.9 2 0 0 2 2 2 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Pkinase PF00069.25 RKO97867.1 - 7.9e-48 163.1 0.0 4.8e-32 111.4 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97867.1 - 1.2e-34 119.7 0.0 1.4e-32 113.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 RKO97867.1 - 0.0078 15.0 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 RKO97867.1 - 0.017 15.1 0.0 0.062 13.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pam17 PF08566.10 RKO97868.1 - 1e-40 139.3 0.1 1.1e-40 139.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Radical_SAM PF04055.21 RKO97868.1 - 0.17 12.2 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Radical SAM superfamily PPR_2 PF13041.6 RKO97870.1 - 0.03 14.5 0.0 2.4 8.4 0.0 3.2 3 0 0 3 3 3 0 PPR repeat family Peptidase_M16 PF00675.20 RKO97870.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) PPR_3 PF13812.6 RKO97870.1 - 0.15 12.1 0.0 0.72 10.0 0.0 2.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain zf-C2H2 PF00096.26 RKO97871.1 - 6.8e-10 38.9 12.9 0.00042 20.6 1.2 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO97871.1 - 1.2e-09 38.2 11.9 0.0016 19.1 0.7 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKO97871.1 - 0.00034 20.9 17.5 0.96 10.0 4.8 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 RKO97871.1 - 0.0038 17.2 3.1 0.027 14.5 0.3 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKO97871.1 - 0.0085 15.8 0.9 0.12 12.1 0.5 2.4 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-DNA_Pol PF08996.10 RKO97871.1 - 0.021 14.6 1.1 0.028 14.2 1.1 1.3 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2HC_2 PF13913.6 RKO97871.1 - 0.051 13.5 2.6 0.076 12.9 0.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.8 RKO97871.1 - 0.15 12.4 6.0 0.28 11.5 0.2 3.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 RKO97871.1 - 0.22 11.3 0.4 0.22 11.3 0.4 3.4 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 RKO97872.1 - 1.6e-09 37.7 7.4 2.1e-05 24.7 1.1 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKO97872.1 - 2.4e-08 34.0 3.9 3.9e-07 30.2 1.9 2.4 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKO97872.1 - 0.00013 22.5 6.0 0.029 15.2 0.6 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 RKO97872.1 - 0.094 12.9 1.1 10 6.3 0.1 2.1 1 1 1 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 RKO97872.1 - 1.3 8.9 3.6 0.95 9.3 0.6 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type MBOAT PF03062.19 RKO97873.1 - 4.1e-33 115.2 22.0 5e-33 114.9 22.0 1.0 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 RKO97873.1 - 0.00035 20.8 4.7 0.0005 20.3 3.6 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family zf-C2H2 PF00096.26 RKO97874.1 - 7.4e-09 35.6 6.8 0.00061 20.1 2.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO97874.1 - 9.1e-09 35.4 5.1 0.0018 18.9 1.9 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKO97874.1 - 1.3e-05 25.4 2.4 0.12 12.7 2.6 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKO97874.1 - 4.1e-05 23.5 4.2 0.051 13.6 2.0 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 RKO97874.1 - 0.0008 19.7 11.5 0.0033 17.8 0.5 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2HE PF16278.5 RKO97874.1 - 0.0028 18.1 1.1 0.33 11.4 0.1 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 RKO97874.1 - 0.014 15.6 0.8 0.02 15.1 0.8 1.2 1 0 0 1 1 1 0 TFIIH C1-like domain zf-met PF12874.7 RKO97874.1 - 0.018 15.4 3.3 1.7 9.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 RKO97874.1 - 3.2 7.6 5.3 16 5.4 0.0 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Peptidase_M24 PF00557.24 RKO97875.1 - 2.3e-47 161.4 0.0 2.8e-47 161.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 RKO97875.1 - 1.7e-14 53.8 8.5 3.7e-14 52.7 8.5 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 RKO97875.1 - 0.00017 21.6 7.6 0.00037 20.5 7.6 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 RKO97875.1 - 0.23 11.3 5.9 0.14 12.0 3.9 1.8 2 0 0 2 2 2 0 HIT zinc finger Pex2_Pex12 PF04757.14 RKO97876.1 - 1e-12 48.2 0.8 1e-06 28.5 0.0 2.1 1 1 1 2 2 2 2 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 RKO97876.1 - 3.3e-09 36.5 10.3 5e-09 35.9 10.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 RKO97876.1 - 1.6e-08 34.8 11.7 2.3e-08 34.2 11.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 RKO97876.1 - 5.3e-08 32.6 10.7 7.6e-08 32.1 10.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 RKO97876.1 - 6.7e-07 29.1 11.9 1e-06 28.5 11.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 RKO97876.1 - 7.7e-07 29.2 10.2 1.3e-06 28.5 10.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 RKO97876.1 - 9e-07 28.7 9.9 1.3e-06 28.2 9.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO97876.1 - 1.3e-06 28.3 3.9 1.3e-06 28.3 2.2 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 RKO97876.1 - 3.8e-06 27.1 9.1 6.1e-06 26.4 9.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 RKO97876.1 - 2.9e-05 23.9 9.1 4.7e-05 23.3 9.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 RKO97876.1 - 0.043 13.9 6.0 0.069 13.2 6.0 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 RKO97876.1 - 0.094 12.9 6.7 0.16 12.1 6.7 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_6 PF14835.6 RKO97876.1 - 0.3 11.0 6.4 0.55 10.1 6.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DiS_P_DiS PF06750.13 RKO97876.1 - 0.39 10.9 2.6 0.75 9.9 2.6 1.5 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain zf-WRNIP1_ubi PF18279.1 RKO97876.1 - 2.3 9.1 4.7 2.2 9.1 0.4 2.6 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_4 PF14570.6 RKO97876.1 - 8.4 6.3 15.4 40 4.1 15.6 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain VWA_2 PF13519.6 RKO97877.1 - 0.0028 18.3 0.0 0.0053 17.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain PatG_D PF18047.1 RKO97877.1 - 0.02 15.3 0.0 0.042 14.3 0.0 1.4 1 1 1 2 2 2 0 PatG Domain Sds3 PF08598.11 RKO97878.1 - 5.9e-14 52.6 8.9 6.7e-14 52.4 8.9 1.0 1 0 0 1 1 1 1 Sds3-like DUF2315 PF10231.9 RKO97878.1 - 0.021 14.9 1.1 0.029 14.5 0.2 1.7 1 1 0 1 1 1 0 Apoptogenic protein 1 GrpE PF01025.19 RKO97878.1 - 6.3 6.4 8.4 1 9.0 1.0 2.1 2 0 0 2 2 2 0 GrpE MSP1_C PF07462.11 RKO97879.1 - 3.5 6.2 5.6 4.4 5.9 5.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Arm PF00514.23 RKO97880.1 - 3.6e-19 68.1 24.6 8.6e-07 28.8 0.0 11.0 12 0 0 12 12 12 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 RKO97880.1 - 2.4e-08 34.2 6.1 1.6 9.2 0.0 7.2 4 2 3 7 7 7 3 HEAT repeats HEAT PF02985.22 RKO97880.1 - 0.002 18.2 22.1 0.96 9.9 0.2 7.9 9 0 0 9 9 9 2 HEAT repeat DUF3361 PF11841.8 RKO97880.1 - 0.005 16.8 4.0 0.0095 15.9 1.1 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 RKO97880.1 - 0.0072 16.5 0.8 1.6 9.0 0.1 3.0 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 RKO97880.1 - 0.0091 16.1 3.6 0.28 11.2 1.6 3.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 DUF913 PF06025.12 RKO97880.1 - 0.028 13.4 0.2 0.84 8.5 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) HEAT_EZ PF13513.6 RKO97880.1 - 1.7 9.3 27.0 0.55 10.8 1.1 8.0 7 2 2 9 9 9 0 HEAT-like repeat Iso_dh PF00180.20 RKO97881.1 - 2.8e-91 306.3 0.0 3.7e-91 305.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ago_PAZ PF18309.1 RKO97881.1 - 0.14 12.8 0.0 0.27 11.9 0.0 1.4 1 0 0 1 1 1 0 Argonaute PAZ domain Sporozoite_P67 PF05642.11 RKO97882.1 - 1.4 6.9 4.8 1.5 6.8 4.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pro_isomerase PF00160.21 RKO97883.1 - 3.5e-44 150.9 0.0 3.9e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Myosin_head PF00063.21 RKO97884.1 - 3.5e-240 798.8 0.0 4.3e-240 798.5 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 RKO97884.1 - 2.9e-44 151.0 0.7 4.9e-44 150.3 0.7 1.3 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 RKO97884.1 - 5.8e-18 64.5 0.4 1.2e-17 63.4 0.4 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO97884.1 - 2e-15 56.1 0.0 4.1e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 RKO97884.1 - 1.7e-11 43.6 0.0 4.8e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.6 RKO97884.1 - 0.011 16.0 0.1 0.23 11.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 RKO97884.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 RKO97884.1 - 0.087 12.1 0.0 0.087 12.1 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin IQ PF00612.27 RKO97884.1 - 0.14 12.0 1.0 0.38 10.7 1.0 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif RNase_PH PF01138.21 RKO97885.1 - 1.7e-14 54.4 0.1 1.7e-14 54.4 0.1 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 RKO97885.1 - 1.4e-08 34.7 0.0 2.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3418 PF11898.8 RKO97885.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) UCR_UQCRX_QCR9 PF05365.12 RKO97886.1 - 1.9e-20 72.6 1.2 1.9e-20 72.6 1.2 1.4 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DNA_primase_S PF01896.19 RKO97887.1 - 2e-42 145.2 0.0 2.7e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 DNA primase small subunit PMI_typeI PF01238.21 RKO97889.1 - 2.9e-114 382.2 0.0 3.4e-114 381.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 RKO97889.1 - 7.3e-06 25.6 0.0 0.0086 15.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain DSPn PF14671.6 RKO97890.1 - 4.9e-39 134.0 0.2 2.4e-38 131.7 0.1 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 RKO97890.1 - 3.6e-13 49.5 0.1 1.1e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 RKO97890.1 - 1.7e-06 27.8 0.0 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 RKO97890.1 - 0.00042 20.5 0.1 0.00075 19.6 0.1 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 RKO97890.1 - 0.0013 18.8 0.0 0.0018 18.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 RKO97890.1 - 0.079 12.5 0.0 0.3 10.7 0.0 1.8 1 1 1 2 2 2 0 Tyrosine phosphatase family HI0933_like PF03486.14 RKO97890.1 - 0.098 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein CPG4 PF15481.6 RKO97891.1 - 0.038 14.6 1.3 0.063 13.9 1.3 1.4 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 YjeJ PF15922.5 RKO97891.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 YjeJ-like Ribosomal_L37 PF08561.10 RKO97892.1 - 6.5e-15 55.7 0.5 1e-14 55.1 0.5 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 ADK PF00406.22 RKO97893.1 - 8.1e-43 146.1 0.0 9.7e-43 145.9 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 RKO97893.1 - 1.3e-18 67.8 0.0 2.8e-18 66.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 RKO97893.1 - 1.2e-15 57.2 0.1 2.3e-15 56.3 0.0 1.5 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 RKO97893.1 - 0.00013 22.5 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 RKO97893.1 - 0.0044 17.2 0.0 0.0084 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain Cytidylate_kin PF02224.18 RKO97893.1 - 0.0083 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Cytidylate kinase AAA_5 PF07728.14 RKO97893.1 - 0.07 13.1 0.1 0.38 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 RKO97893.1 - 0.14 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Flavin_Reduct PF01613.18 RKO97894.1 - 6.5e-18 65.2 0.0 7.8e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 Flavin reductase like domain WD40 PF00400.32 RKO97896.1 - 1.7e-18 66.6 9.0 2e-06 28.4 1.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97896.1 - 4.9e-09 36.4 0.5 0.039 14.2 0.2 4.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 RKO97896.1 - 4.3e-07 29.0 0.6 0.0035 16.0 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 RKO97896.1 - 0.00086 18.7 0.8 0.0067 15.8 0.2 2.1 3 0 0 3 3 3 1 WD40-like domain Cytochrom_D1 PF02239.16 RKO97896.1 - 0.008 14.7 0.0 0.75 8.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 RKO97896.1 - 0.0092 15.0 1.0 1.6 7.6 0.0 3.6 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 RKO97896.1 - 0.023 14.7 0.1 21 5.2 0.0 3.3 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region UQ_con PF00179.26 RKO97897.1 - 4.4e-46 156.0 0.0 4.9e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 RKO97897.1 - 0.00079 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 RKO97897.1 - 0.0024 17.6 0.0 0.0031 17.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 RKO97897.1 - 0.014 15.7 0.0 0.016 15.5 0.0 1.3 1 0 0 1 1 1 0 RWD domain CDT1 PF08839.11 RKO97900.1 - 4.1e-20 72.8 0.0 7e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 RKO97900.1 - 7.1e-12 45.6 0.2 2.3e-11 44.0 0.2 1.9 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Thr_synth_N PF14821.6 RKO97901.1 - 3.1e-27 94.6 0.0 9.1e-27 93.1 0.0 1.9 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 RKO97901.1 - 3.9e-15 56.1 0.1 2e-14 53.7 0.1 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltr_RsmB-F PF01189.17 RKO97902.1 - 6.9e-30 104.2 0.0 2.1e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 RKO97902.1 - 0.0047 17.1 0.0 0.0088 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fibrillarin PF01269.17 RKO97902.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Not3 PF04065.15 RKO97903.1 - 1.4e-89 299.6 20.5 1.8e-89 299.2 20.5 1.1 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 RKO97903.1 - 7.4e-38 129.6 1.4 7.4e-38 129.6 1.4 1.9 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 RKO97903.1 - 0.12 12.7 3.9 0.12 12.8 0.9 2.2 2 0 0 2 2 2 0 Syntaxin-like protein Sin3_corepress PF08295.12 RKO97903.1 - 2.1 8.5 5.7 34 4.6 0.0 3.5 3 1 1 4 4 4 0 Sin3 family co-repressor DnaJ PF00226.31 RKO97904.1 - 1.2e-20 73.3 1.2 3.6e-20 71.8 0.6 2.1 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 RKO97904.1 - 1.4e-10 40.5 19.5 0.083 13.1 0.1 8.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 RKO97904.1 - 1e-09 38.6 14.9 8.6e-05 22.8 0.3 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKO97904.1 - 1.4e-09 37.3 8.7 0.23 11.3 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 RKO97904.1 - 2.5e-07 31.1 17.7 0.048 14.2 0.6 5.3 4 2 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 RKO97904.1 - 1e-05 25.3 2.2 12 6.4 0.3 6.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 RKO97904.1 - 0.00058 19.7 12.0 25 5.2 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_16 PF13432.6 RKO97904.1 - 0.0015 19.1 30.0 0.0062 17.2 0.1 6.9 5 2 2 7 7 6 2 Tetratricopeptide repeat DUF4129 PF13559.6 RKO97904.1 - 0.0052 17.0 2.3 0.0052 17.0 2.3 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4129) TPR_17 PF13431.6 RKO97904.1 - 0.022 15.1 8.2 1.9 9.1 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 RKO97904.1 - 0.027 14.6 11.0 1.6 8.9 0.0 5.4 6 1 1 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 RKO97904.1 - 0.091 12.7 5.4 0.71 9.8 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat HEAT_2 PF13646.6 RKO97904.1 - 0.19 12.1 3.9 0.21 12.0 1.8 2.3 2 0 0 2 2 1 0 HEAT repeats Alkyl_sulf_dimr PF14863.6 RKO97904.1 - 0.38 11.2 0.1 0.38 11.2 0.1 3.7 2 2 3 5 5 4 0 Alkyl sulfatase dimerisation TPR_9 PF13371.6 RKO97904.1 - 0.48 10.6 16.5 14 5.9 1.2 5.8 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKO97904.1 - 0.71 10.6 20.4 1.1 10.1 0.1 6.8 6 1 1 7 7 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO97904.1 - 1.3 9.3 20.6 1.1 9.5 0.0 5.4 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 Gluconate_2-dh3 PF13618.6 RKO97904.1 - 4.2 7.6 7.0 57 3.9 0.2 3.9 3 1 1 4 4 4 0 Gluconate 2-dehydrogenase subunit 3 TAL_FSA PF00923.19 RKO97905.1 - 2.7e-87 292.8 0.7 4.1e-87 292.2 0.7 1.3 1 1 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF3767 PF12597.8 RKO97906.1 - 4.7e-18 64.9 0.4 4.9e-18 64.8 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Phage_holin_2_3 PF16080.5 RKO97906.1 - 1 9.2 4.3 1.4 8.8 0.2 2.2 1 1 1 2 2 2 0 Bacteriophage holin family HP1 DUF3449 PF11931.8 RKO97907.1 - 4e-60 202.8 0.0 4.4e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) DEAD PF00270.29 RKO97908.1 - 5.3e-42 143.6 0.2 1.1e-41 142.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO97908.1 - 2.5e-31 108.3 0.0 1.1e-30 106.2 0.0 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 RKO97908.1 - 0.00038 20.2 0.3 0.00094 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 RKO97908.1 - 0.0016 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 RKO97908.1 - 0.014 15.8 0.2 0.073 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 RKO97908.1 - 0.038 14.3 0.0 0.09 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain GPI2 PF06432.11 RKO97909.1 - 2.8e-67 227.1 2.7 3.1e-67 227.0 2.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase YqhR PF11085.8 RKO97909.1 - 0.032 14.2 0.6 0.032 14.2 0.6 2.0 2 1 0 2 2 2 0 Conserved membrane protein YqhR DUF3932 PF13068.6 RKO97909.1 - 0.051 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) LSM PF01423.22 RKO97910.1 - 5.7e-19 67.6 0.1 6.9e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 RKO97910.1 - 0.0028 17.2 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 Hfq protein CN_hydrolase PF00795.22 RKO97911.1 - 2.3e-40 138.6 0.0 3.4e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 RKO97911.1 - 4e-22 78.5 0.0 3.8e-21 75.3 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.21 RKO97911.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Acetyltransf_1 PF00583.25 RKO97912.1 - 4.2e-10 39.9 0.0 6.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 RKO97912.1 - 1.2e-07 31.7 0.1 1.8e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 RKO97912.1 - 2.7e-06 27.7 0.0 4.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 RKO97912.1 - 7.1e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein CNOT1_TTP_bind PF16417.5 RKO97913.1 - 1.2e-52 177.9 0.0 2.1e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_CAF1_bind PF16415.5 RKO97913.1 - 3.7e-39 134.4 0.1 5.4e-39 133.9 0.1 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain NRIP1_repr_3 PF15689.5 RKO97914.1 - 0.2 12.0 1.3 0.42 10.9 0.4 2.1 1 1 1 2 2 2 0 Nuclear receptor-interacting protein 1 repression 3 Host_attach PF10116.9 RKO97914.1 - 0.57 10.7 4.7 0.32 11.5 2.1 1.9 1 1 1 2 2 2 0 Protein required for attachment to host cells WD40 PF00400.32 RKO97915.1 - 0.00018 22.2 7.8 11 7.0 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97915.1 - 0.00067 19.9 0.0 0.3 11.4 0.0 2.9 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 RKO97915.1 - 0.0029 17.7 9.1 0.0066 16.5 9.1 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 OmpH PF03938.14 RKO97915.1 - 0.73 10.2 10.4 1.4 9.3 10.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Siah-Interact_N PF09032.11 RKO97915.1 - 1.6 9.1 7.0 4 7.8 7.0 1.7 1 0 0 1 1 1 0 Siah interacting protein, N terminal Spt20 PF12090.8 RKO97915.1 - 4.7 6.7 9.3 7.5 6.1 9.3 1.2 1 0 0 1 1 1 0 Spt20 family API5 PF05918.11 RKO97915.1 - 6.9 5.4 6.2 9.7 4.9 6.2 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) UPF0121 PF03661.13 RKO97916.1 - 2.6e-34 118.7 5.9 3e-34 118.5 5.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Ribosomal_L7Ae PF01248.26 RKO97917.1 - 8.3e-25 86.4 0.0 1.1e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 RKO97917.1 - 0.00074 19.4 0.0 0.00099 18.9 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 RKO97917.1 - 0.072 13.1 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 E1-E2_ATPase PF00122.20 RKO97918.1 - 5e-39 133.7 2.6 9.3e-38 129.6 0.2 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 RKO97918.1 - 1.3e-18 68.1 0.0 2.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 RKO97918.1 - 1.2e-07 31.3 0.0 3e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 RKO97918.1 - 0.0016 18.3 0.1 0.003 17.4 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GNVR PF13807.6 RKO97918.1 - 0.089 12.7 0.1 4.9 7.1 0.0 2.9 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase YrvL PF14184.6 RKO97918.1 - 3.1 7.9 10.9 0.064 13.4 3.1 2.1 2 0 0 2 2 2 0 Regulatory protein YrvL LSM PF01423.22 RKO97920.1 - 3.1e-19 68.4 0.9 4.4e-19 67.9 0.9 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 RKO97920.1 - 0.0068 16.5 0.2 0.0089 16.1 0.2 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain SelK_SelG PF10961.8 RKO97920.1 - 0.045 14.4 8.0 0.074 13.7 8.0 1.4 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Ras PF00071.22 RKO97922.1 - 6.7e-54 181.8 0.0 7.8e-54 181.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO97922.1 - 1.3e-21 77.0 0.0 2.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO97922.1 - 9.9e-08 31.6 0.0 1.2e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO97922.1 - 0.0027 17.3 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LIM PF00412.22 RKO97923.1 - 5.6e-08 32.9 6.1 8.4e-08 32.3 6.1 1.2 1 0 0 1 1 1 1 LIM domain PK PF00224.21 RKO97924.1 - 7.1e-102 340.8 0.5 9e-102 340.5 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 RKO97924.1 - 8.3e-25 87.3 0.5 2e-24 86.1 0.1 1.8 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain Metallophos PF00149.28 RKO97925.1 - 4.6e-40 138.3 0.1 6e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 RKO97925.1 - 4.6e-22 78.2 1.1 1.1e-21 77.0 0.7 1.8 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Importin_rep PF18773.1 RKO97925.1 - 0.13 12.0 0.1 0.95 9.2 0.0 2.3 2 0 0 2 2 2 0 Importin 13 repeat Band_7 PF01145.25 RKO97926.1 - 2.5e-14 53.7 2.2 3.4e-14 53.2 2.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 RKO97926.1 - 0.00096 18.3 1.2 0.0012 18.0 1.2 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Ribosomal_S30 PF04758.14 RKO97927.1 - 8.8e-24 83.5 4.4 9.7e-24 83.3 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Got1 PF04178.12 RKO97928.1 - 4.3e-15 56.1 11.4 5.3e-15 55.8 11.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 RKO97928.1 - 1.2 9.5 19.6 0.094 13.1 14.4 1.8 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) adh_short PF00106.25 RKO97929.1 - 6.9e-33 113.8 3.0 8.4e-33 113.5 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 RKO97929.1 - 1e-20 74.3 5.0 1.2e-20 74.1 5.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 RKO97929.1 - 2.7e-12 47.0 2.0 4.4e-12 46.3 2.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 RKO97929.1 - 1.7e-05 24.5 0.8 2.9e-05 23.7 0.8 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 RKO97929.1 - 0.0015 17.8 4.1 0.44 9.7 0.0 2.9 1 1 2 3 3 3 2 Male sterility protein NAD_binding_10 PF13460.6 RKO97929.1 - 0.047 13.6 3.1 0.079 12.8 3.1 1.5 1 1 0 1 1 1 0 NAD(P)H-binding SPT16 PF08644.11 RKO97930.1 - 2.1e-49 167.6 0.0 2.1e-49 167.6 0.0 2.4 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 RKO97930.1 - 2.8e-32 111.8 0.1 1.5e-31 109.4 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 RKO97930.1 - 1.1e-25 90.6 0.0 1.8e-25 89.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 RKO97930.1 - 2.9e-14 53.2 0.1 7.3e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DOT1 PF08123.13 RKO97931.1 - 3.9e-63 212.7 0.0 4.9e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.20 RKO97931.1 - 0.00014 21.3 0.2 0.00075 18.9 0.0 2.1 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 RKO97931.1 - 0.0089 15.9 0.0 0.025 14.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO97931.1 - 0.01 16.5 0.1 0.05 14.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PCMT PF01135.19 RKO97931.1 - 0.021 14.6 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 RKO97931.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 RKO97931.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase SesA PF17107.5 RKO97932.1 - 0.35 11.1 1.9 1.5 9.1 0.1 2.7 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NDUFA12 PF05071.16 RKO97933.1 - 5.7e-28 97.6 4.3 6.6e-28 97.4 4.3 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Peptidase_M24 PF00557.24 RKO97934.1 - 1.9e-34 119.2 0.2 8.1e-33 113.9 0.2 2.6 1 1 0 1 1 1 1 Metallopeptidase family M24 DHHC PF01529.20 RKO97934.1 - 3.9e-27 95.0 0.0 6.2e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase AMP_N PF05195.16 RKO97934.1 - 2.6e-17 62.7 0.0 4.6e-16 58.7 0.0 2.3 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain FYVE PF01363.21 RKO97934.1 - 4.2 7.6 10.0 10 6.4 10.0 1.5 1 0 0 1 1 1 0 FYVE zinc finger Aa_trans PF01490.18 RKO97935.1 - 8.2e-53 179.6 21.3 9.6e-53 179.4 21.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF155 PF02582.14 RKO97936.1 - 1.4e-37 129.4 0.0 2.7e-37 128.6 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Proteasome PF00227.26 RKO97937.1 - 3.3e-58 196.3 0.2 4e-58 196.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKO97937.1 - 7.4e-14 51.1 0.1 1.3e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature NUDE_C PF04880.13 RKO97938.1 - 4.4 7.7 10.7 2.7 8.4 9.3 1.4 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region F-box PF00646.33 RKO97940.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 RKO97940.1 - 0.27 11.1 3.9 0.095 12.6 1.0 1.7 2 0 0 2 2 2 0 F-box-like RL10P_insert PF17777.1 RKO97941.1 - 2e-23 82.2 0.1 5.6e-23 80.7 0.0 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 RKO97941.1 - 1.9e-22 79.2 0.0 3.9e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 RKO97941.1 - 1.7e-15 57.3 3.8 1.7e-15 57.3 3.8 1.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.32 RKO97942.1 - 9e-23 80.1 14.9 8.6e-09 35.9 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 RKO97942.1 - 4.6e-07 28.9 8.5 0.0077 14.9 0.0 4.9 1 1 3 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 RKO97942.1 - 6.7e-06 26.3 0.0 0.16 12.3 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 RKO97942.1 - 0.00012 22.4 1.9 0.09 13.3 0.0 4.6 5 0 0 5 5 5 1 PQQ-like domain Nucleoporin_N PF08801.11 RKO97942.1 - 0.0018 17.1 0.0 0.94 8.1 0.0 2.4 2 0 0 2 2 2 2 Nup133 N terminal like PALB2_WD40 PF16756.5 RKO97942.1 - 0.0022 17.0 0.3 1.8 7.4 0.0 3.2 2 2 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain PHTB1_N PF14727.6 RKO97942.1 - 0.099 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 PTHB1 N-terminus DUF3632 PF12311.8 RKO97943.1 - 0.027 14.9 0.2 0.043 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3632) Proteasome PF00227.26 RKO97944.1 - 6.4e-54 182.3 0.1 8.4e-54 181.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKO97944.1 - 2.8e-14 52.4 0.1 5.7e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RuvA_C PF07499.13 RKO97944.1 - 0.12 12.8 0.3 0.36 11.3 0.1 2.0 2 0 0 2 2 2 0 RuvA, C-terminal domain eIF-3_zeta PF05091.12 RKO97945.1 - 4.4e-168 560.5 0.0 5.2e-168 560.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) HipN PF18253.1 RKO97945.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain NARG2_C PF10505.9 RKO97945.1 - 0.21 11.1 0.0 1.6 8.2 0.0 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus UQ_con PF00179.26 RKO97946.1 - 1.6e-45 154.2 0.0 2e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UPF0004 PF00919.20 RKO97947.1 - 1.6e-16 60.2 0.0 4.8e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 RKO97947.1 - 2.1e-16 60.7 0.0 9.2e-16 58.7 0.0 1.9 1 1 0 1 1 1 1 Radical SAM superfamily DUF374 PF04028.13 RKO97947.1 - 0.015 14.8 0.0 0.054 13.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF374) Glyco_hydro_26 PF02156.15 RKO97948.1 - 3.7e-11 43.0 0.6 5.4e-05 22.8 0.4 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 ETRAMP PF09716.10 RKO97948.1 - 0.097 12.7 0.1 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase PF00069.25 RKO97949.1 - 2.8e-64 217.0 0.0 3.2e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97949.1 - 3.6e-30 105.1 0.0 8.7e-30 103.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO97949.1 - 0.00024 20.5 0.0 0.0022 17.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 RKO97949.1 - 0.004 16.2 0.0 0.088 11.7 0.0 2.1 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 RKO97949.1 - 0.007 16.3 0.0 0.013 15.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 RKO97949.1 - 0.042 12.6 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 RKO97949.1 - 0.053 12.9 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRM_1 PF00076.22 RKO97950.1 - 7.2e-19 67.4 0.6 8.5e-19 67.2 0.0 1.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 RKO97950.1 - 1.9e-05 24.2 0.0 2.3e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4355 PF14265.6 RKO97950.1 - 0.079 13.2 1.9 0.11 12.7 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) RRM_Rrp7 PF17799.1 RKO97950.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain GCP_C_terminal PF04130.13 RKO97951.1 - 6.1e-46 157.3 0.0 1e-45 156.6 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 RKO97951.1 - 3.6e-44 151.6 0.0 6.2e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF1115 PF06544.12 RKO97952.1 - 1.2e-27 96.8 0.0 4.2e-27 95.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) PRP3 PF08572.10 RKO97952.1 - 7.4e-16 58.6 0.2 1.1e-15 58.0 0.2 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) L31 PF09784.9 RKO97953.1 - 6.9e-15 55.3 0.4 8.1e-15 55.1 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 TPR_2 PF07719.17 RKO97954.1 - 1.2e-38 128.1 18.8 5.7e-05 22.9 0.5 11.7 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_1 PF00515.28 RKO97954.1 - 2.4e-34 115.7 22.9 4.2e-07 29.5 1.3 11.7 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 RKO97954.1 - 3.3e-23 79.9 11.7 0.011 15.9 0.2 11.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 RKO97954.1 - 5.3e-23 81.3 26.0 0.00019 21.9 5.0 7.8 6 2 2 9 9 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 RKO97954.1 - 1.6e-20 73.4 30.5 4.9e-08 33.5 0.9 7.9 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 RKO97954.1 - 1.1e-18 66.6 23.6 4.2e-06 26.3 2.4 8.6 6 2 3 9 9 8 4 TPR repeat TPR_12 PF13424.6 RKO97954.1 - 5.6e-18 65.0 38.9 1.3e-06 28.6 1.8 9.5 5 4 5 10 10 10 7 Tetratricopeptide repeat TPR_14 PF13428.6 RKO97954.1 - 2e-17 62.4 29.5 0.26 12.2 0.1 11.7 7 2 4 12 12 11 6 Tetratricopeptide repeat TPR_6 PF13174.6 RKO97954.1 - 1.1e-13 50.8 27.9 0.034 14.8 0.1 11.8 12 0 0 12 12 11 2 Tetratricopeptide repeat ANAPC3 PF12895.7 RKO97954.1 - 1.1e-13 51.2 23.9 2.2e-06 27.8 5.4 6.4 5 4 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 RKO97954.1 - 2.3e-12 46.0 31.8 0.0095 15.9 0.1 11.0 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 RKO97954.1 - 3e-08 33.5 24.2 0.0051 17.1 0.0 7.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_10 PF13374.6 RKO97954.1 - 1.8e-06 27.6 24.3 0.18 11.7 0.0 8.6 10 0 0 10 10 10 3 Tetratricopeptide repeat BTAD PF03704.17 RKO97954.1 - 3e-06 27.7 11.3 0.039 14.4 0.5 4.8 3 1 1 4 4 4 2 Bacterial transcriptional activator domain TPR_9 PF13371.6 RKO97954.1 - 3.6e-05 23.8 10.0 0.17 12.0 0.8 6.0 2 2 5 7 7 7 2 Tetratricopeptide repeat DUF2225 PF09986.9 RKO97954.1 - 0.00017 21.4 1.5 0.5 10.0 0.2 3.5 2 2 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 RKO97954.1 - 0.00045 20.0 21.9 1.4 8.6 0.1 7.3 4 3 1 6 6 6 2 26S proteasome subunit RPN7 Coatomer_E PF04733.14 RKO97954.1 - 0.005 16.3 0.9 0.022 14.2 0.1 2.5 2 1 0 2 2 2 1 Coatomer epsilon subunit DUF4810 PF16068.5 RKO97954.1 - 0.0069 16.9 1.9 13 6.4 0.0 5.5 6 1 1 7 7 5 0 Domain of unknown function (DUF4810) TPR_20 PF14561.6 RKO97954.1 - 0.02 15.2 14.0 0.024 14.9 0.6 5.2 2 2 3 6 6 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 RKO97954.1 - 0.021 14.3 0.0 6.3 6.3 0.0 3.5 4 0 0 4 4 4 0 SHNi-TPR NARP1 PF12569.8 RKO97954.1 - 0.038 12.9 9.8 0.38 9.6 0.0 3.7 3 1 2 5 5 5 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.14 RKO97954.1 - 0.56 11.0 12.4 13 6.7 0.1 7.5 11 0 0 11 11 5 0 Tetratricopeptide repeat MIT PF04212.18 RKO97954.1 - 1.3 9.1 23.5 33 4.6 0.1 7.7 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.12 RKO97954.1 - 2.1 9.1 8.4 16 6.4 0.1 5.5 6 0 0 6 6 5 0 Sel1 repeat ATP-synt PF00231.19 RKO97955.1 - 2.9e-72 243.7 11.9 3.3e-72 243.6 11.9 1.0 1 0 0 1 1 1 1 ATP synthase INCENP_ARK-bind PF03941.15 RKO97955.1 - 0.0028 17.5 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Cactin_mid PF10312.9 RKO97955.1 - 0.0067 16.2 1.4 0.0075 16.0 0.2 1.7 2 0 0 2 2 2 1 Conserved mid region of cactin CRM1_C PF08767.11 RKO97956.1 - 5.5e-129 429.9 10.5 5.6e-129 429.9 1.4 3.1 3 0 0 3 3 3 2 CRM1 C terminal Xpo1 PF08389.12 RKO97956.1 - 1.8e-41 141.6 5.6 1.8e-41 141.6 5.6 3.9 5 1 1 6 6 6 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 RKO97956.1 - 8.9e-29 98.9 2.6 2.6e-28 97.4 2.6 1.9 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 RKO97956.1 - 7.9e-27 93.1 1.8 7.9e-27 93.1 1.8 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 RKO97956.1 - 5.5e-19 67.4 0.9 1.3e-18 66.1 0.9 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 RKO97956.1 - 3e-13 49.5 0.2 1e-12 47.8 0.2 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain MMS19_C PF12460.8 RKO97956.1 - 0.0062 15.7 6.1 0.28 10.3 0.1 3.8 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 RKO97956.1 - 0.043 13.7 6.9 4.5 7.2 0.0 4.4 6 0 0 6 6 6 0 Domain of unknown function (DUF3385) PEX11 PF05648.14 RKO97956.1 - 0.12 11.8 0.2 0.23 10.9 0.2 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) UCH PF00443.29 RKO97956.1 - 0.24 10.9 0.4 7.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Prolamin_like PF05617.11 RKO97956.1 - 0.55 10.4 2.2 20 5.5 0.1 3.4 3 0 0 3 3 3 0 Prolamin-like Med18 PF09637.10 RKO97957.1 - 3.1e-16 60.0 0.0 1.4e-12 48.0 0.0 2.5 2 1 0 2 2 2 2 Med18 protein Arrestin_N PF00339.29 RKO97957.1 - 3.5e-11 43.3 0.0 6.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 RKO97957.1 - 0.0066 16.9 0.0 0.043 14.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 RKO97957.1 - 0.21 10.7 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Rgp1 Prenyltrans PF00432.21 RKO97958.1 - 3.4e-49 164.3 12.5 6.4e-11 41.8 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 RKO97958.1 - 0.11 11.6 0.0 16 4.5 0.0 3.4 2 2 1 4 4 4 0 Squalene-hopene cyclase N-terminal domain KIAA1430 PF13879.6 RKO97959.1 - 2.7e-09 37.7 1.8 9.4e-05 23.1 0.0 3.0 1 1 2 3 3 3 3 KIAA1430 homologue ASD2 PF08687.11 RKO97959.1 - 0.0082 15.7 1.6 0.013 15.0 1.6 1.3 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Tocopherol_cycl PF14249.6 RKO97960.1 - 2.5e-09 36.7 0.0 0.0038 16.4 0.0 3.2 3 1 0 3 3 3 2 Tocopherol cyclase AAA PF00004.29 RKO97961.1 - 1.2e-41 142.2 0.0 2.4e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 RKO97961.1 - 1.8e-18 66.3 0.1 3.4e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 RKO97961.1 - 1.1e-08 34.7 0.3 2.6e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKO97961.1 - 1.1e-05 25.4 0.1 8.7e-05 22.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 RKO97961.1 - 5e-05 23.5 0.8 0.00017 21.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RKO97961.1 - 0.0001 22.1 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 RKO97961.1 - 0.0001 22.7 0.4 0.015 15.7 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 RKO97961.1 - 0.00035 20.8 0.9 0.091 13.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 RKO97961.1 - 0.0027 17.2 0.0 0.035 13.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 RKO97961.1 - 0.014 15.2 0.3 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 RKO97961.1 - 0.018 14.4 0.1 0.044 13.2 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 RKO97961.1 - 0.019 15.1 0.0 0.064 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain JIP_LZII PF16471.5 RKO97961.1 - 0.019 15.1 3.7 0.067 13.4 3.7 1.9 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II IstB_IS21 PF01695.17 RKO97961.1 - 0.026 14.2 0.0 0.07 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.13 RKO97961.1 - 0.037 13.2 0.0 0.067 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 RKO97961.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 RKO97961.1 - 0.051 13.3 0.1 0.2 11.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKO97961.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region Glyco_hydr_30_2 PF14587.6 RKO97962.1 - 3.8e-22 79.4 3.8 1.5e-19 70.8 3.8 2.3 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 NYD-SP28_assoc PF14775.6 RKO97963.1 - 1.3e-17 63.7 1.7 1.3e-17 63.7 1.7 4.6 4 1 1 5 5 5 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 RKO97963.1 - 1.7e-17 63.3 12.5 1.7e-17 63.3 12.5 5.9 3 1 4 7 7 7 2 Sperm tail Gcd10p PF04189.13 RKO97965.1 - 7.3e-62 209.2 0.0 9.1e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Gcd10p family Bromodomain PF00439.25 RKO97966.1 - 8.2e-09 35.4 0.0 9e-09 35.3 0.0 1.0 1 0 0 1 1 1 1 Bromodomain MIR PF02815.19 RKO97967.1 - 4.7e-12 46.1 0.3 1.1e-08 35.2 0.1 3.0 1 1 2 3 3 3 3 MIR domain DUF2087 PF09860.9 RKO97968.1 - 0.046 13.9 1.9 0.17 12.0 1.9 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) DUF3584 PF12128.8 RKO97968.1 - 0.3 8.6 34.6 0.41 8.1 34.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prismane PF03063.20 RKO97968.1 - 8 5.0 9.5 12 4.4 9.4 1.3 1 1 0 1 1 1 0 Prismane/CO dehydrogenase family Y_phosphatase3 PF13350.6 RKO97969.1 - 7.4e-38 130.8 0.0 9.1e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 RKO97969.1 - 1.5e-08 34.4 0.1 6.3e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RKO97969.1 - 2.4e-05 24.0 0.0 3.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 RKO97969.1 - 0.0022 17.0 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 RKO97969.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 RKO97969.1 - 0.16 12.1 0.1 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate EamA PF00892.20 RKO97970.1 - 2e-10 41.0 32.0 4.3e-07 30.2 2.1 2.6 2 1 1 3 3 3 2 EamA-like transporter family TMEM234 PF10639.9 RKO97970.1 - 0.00011 22.2 3.6 0.0012 18.9 0.4 2.4 2 0 0 2 2 2 2 Putative transmembrane family 234 Nuc_sug_transp PF04142.15 RKO97970.1 - 0.038 13.2 10.5 0.054 12.7 10.5 1.2 1 0 0 1 1 1 0 Nucleotide-sugar transporter Endonuclease_NS PF01223.23 RKO97971.1 - 1.5e-48 165.6 0.0 1.7e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Endonuclea_NS_2 PF13930.6 RKO97971.1 - 0.094 12.8 0.0 0.3 11.2 0.0 1.7 1 1 0 1 1 1 0 DNA/RNA non-specific endonuclease BOP1NT PF08145.12 RKO97972.1 - 9.2e-87 291.2 5.8 1.4e-86 290.7 5.8 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 RKO97972.1 - 8.6e-29 99.2 6.4 5.3e-08 33.4 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO97972.1 - 8.3e-06 26.0 0.0 0.031 14.6 0.0 4.2 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain IFT57 PF10498.9 RKO97972.1 - 0.11 11.4 8.6 0.17 10.8 8.6 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 FANCL_C PF11793.8 RKO97973.1 - 1.6e-10 41.0 1.8 4e-10 39.7 1.8 1.7 1 0 0 1 1 1 1 FANCL C-terminal domain WD-3 PF09765.9 RKO97973.1 - 2.5e-05 23.8 0.0 4.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 WD-repeat region zf-RING_2 PF13639.6 RKO97973.1 - 0.74 10.2 10.9 4.3 7.8 10.9 2.3 1 1 0 1 1 1 0 Ring finger domain Glyco_hydro_15 PF00723.21 RKO97974.1 - 1.1e-57 195.8 0.3 2e-57 195.0 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Pro_CA PF00484.19 RKO97975.1 - 4.3e-44 150.6 0.4 5.4e-44 150.2 0.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase SSXT PF05030.12 RKO97975.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Amidohydro_2 PF04909.14 RKO97976.1 - 7.7e-11 42.3 0.8 1.5e-10 41.3 0.3 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 RKO97976.1 - 1.6e-09 37.6 0.0 2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Sipho_Gp157 PF05565.11 RKO97976.1 - 0.13 12.3 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 3HCDH_N PF02737.18 RKO97977.1 - 4e-52 176.7 2.3 4e-52 176.7 2.3 1.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 RKO97977.1 - 1.1e-33 115.7 0.0 2.4e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 RKO97978.1 - 2.1e-50 170.7 0.0 4.5e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 RKO97978.1 - 1e-44 152.3 0.2 1.7e-44 151.5 0.2 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 RKO97978.1 - 0.032 14.8 0.0 16 6.2 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 RKO97980.1 - 8.5e-10 38.4 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO97980.1 - 0.025 13.9 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase AA_permease_2 PF13520.6 RKO97981.1 - 4.6e-75 253.1 31.8 5.5e-75 252.8 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 RKO97981.1 - 5.4e-29 101.1 25.5 6.1e-29 100.9 25.5 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M22 PF00814.25 RKO97982.1 - 2.8e-84 283.0 0.0 3.3e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 RKO97982.1 - 0.096 12.3 0.0 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus RRM_1 PF00076.22 RKO97983.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C2-C2_1 PF11618.8 RKO97985.1 - 0.0012 19.0 0.0 0.0034 17.5 0.0 1.8 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 UDG PF03167.19 RKO97986.1 - 3.4e-18 66.1 0.0 4.7e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Ribosomal_L35Ae PF01247.18 RKO97987.1 - 2e-39 133.6 0.1 2.3e-39 133.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 RKO97987.1 - 0.056 13.7 0.0 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 RimM N-terminal domain Pyr_redox_2 PF07992.14 RKO97988.1 - 4.6e-44 150.8 1.3 5.5e-44 150.6 1.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 RKO97988.1 - 1.7e-16 60.5 1.3 6.7e-14 52.2 0.2 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 RKO97988.1 - 2.8e-14 53.1 0.1 3.7e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 RKO97988.1 - 3.1e-05 23.3 0.0 0.00033 19.9 0.0 2.4 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 RKO97988.1 - 0.00042 20.7 0.1 0.01 16.3 0.1 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 RKO97988.1 - 0.0021 17.4 0.1 0.013 14.8 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 RKO97988.1 - 0.019 14.3 0.5 0.084 12.2 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 RKO97988.1 - 0.021 15.1 1.0 0.68 10.2 0.0 2.8 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain SIP PF04954.13 RKO97988.1 - 0.052 14.1 0.1 0.19 12.2 0.0 1.9 2 0 0 2 2 2 0 Siderophore-interacting protein HI0933_like PF03486.14 RKO97988.1 - 0.12 11.0 0.8 14 4.2 0.1 2.8 2 1 0 3 3 3 0 HI0933-like protein GIDA PF01134.22 RKO97988.1 - 0.13 11.3 5.2 1.8 7.6 0.7 3.2 3 1 1 4 4 4 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 RKO97988.1 - 0.25 10.4 7.8 0.32 10.0 0.4 3.6 2 2 1 4 4 4 0 FAD binding domain RGS PF00615.19 RKO97989.1 - 0.0017 18.6 0.1 0.002 18.4 0.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAPA-1 PF04795.12 RKO97990.1 - 3.4e-14 53.4 1.6 3.4e-14 53.4 1.6 5.0 2 1 2 4 4 4 1 PAPA-1-like conserved region Ribosomal_S25 PF03297.15 RKO97991.1 - 8.1e-34 115.9 0.9 8.9e-34 115.7 0.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 RKO97991.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 0 Ftsk gamma domain HTH_24 PF13412.6 RKO97991.1 - 0.013 15.1 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DDRGK PF09756.9 RKO97991.1 - 0.013 15.1 0.1 0.015 14.9 0.1 1.1 1 0 0 1 1 1 0 DDRGK domain MarR_2 PF12802.7 RKO97991.1 - 0.034 14.0 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 MarR family GntR PF00392.21 RKO97991.1 - 0.055 13.1 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_11 PF08279.12 RKO97991.1 - 0.086 12.8 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 HTH domain TRAM_2 PF18693.1 RKO97991.1 - 0.092 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 TRAM domain EAP30 PF04157.16 RKO97991.1 - 0.099 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.11 RKO97991.1 - 0.1 12.2 1.7 0.14 11.7 1.4 1.5 1 1 0 1 1 1 0 CodY helix-turn-helix domain Ras PF00071.22 RKO97992.1 - 3.8e-47 159.9 0.0 4.5e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO97992.1 - 4.5e-27 94.7 0.0 9.8e-27 93.6 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO97992.1 - 2.7e-08 33.5 0.0 3.7e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 RKO97992.1 - 4.4e-05 23.8 0.1 0.00033 21.0 0.1 2.1 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.20 RKO97992.1 - 0.0071 15.5 0.2 0.99 8.5 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Pox_A32 PF04665.12 RKO97992.1 - 0.024 14.1 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein MMR_HSR1 PF01926.23 RKO97992.1 - 0.034 14.2 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 RKO97992.1 - 0.046 13.2 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 RKO97992.1 - 0.049 14.0 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 RKO97992.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgoMid PF16487.5 RKO97992.1 - 0.065 13.5 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 Mid domain of argonaute AAA_24 PF13479.6 RKO97992.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 RKO97992.1 - 0.1 12.5 0.1 9.6 6.1 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 RKO97992.1 - 0.13 12.5 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 RKO97992.1 - 0.16 11.9 0.1 0.26 11.2 0.1 1.3 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 RKO97992.1 - 0.16 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 RKO97992.1 - 0.2 11.9 0.0 0.51 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain Mis12 PF05859.12 RKO97993.1 - 5.5e-24 84.8 0.0 1e-23 83.8 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein DivIC PF04977.15 RKO97993.1 - 0.0062 16.3 2.2 0.011 15.4 2.2 1.3 1 0 0 1 1 1 1 Septum formation initiator ADIP PF11559.8 RKO97993.1 - 0.1 12.7 0.8 0.21 11.6 0.8 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3450 PF11932.8 RKO97993.1 - 2.7 7.2 7.7 0.27 10.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Cwf_Cwc_15 PF04889.12 RKO97993.1 - 2.7 7.7 7.2 0.48 10.1 3.1 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ChAPs PF09295.10 RKO97994.1 - 2.9e-128 428.3 0.0 5e-128 427.5 0.0 1.4 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.6 RKO97994.1 - 6.9e-05 23.3 0.2 0.71 10.4 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat SUIM_assoc PF16619.5 RKO97994.1 - 0.06 13.4 11.5 0.082 13.0 4.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3827 PF12877.7 RKO97994.1 - 0.11 10.8 7.0 0.16 10.3 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Hid1 PF12722.7 RKO97994.1 - 0.19 9.8 3.3 0.27 9.3 3.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CiPC PF15800.5 RKO97994.1 - 0.32 10.7 10.9 0.5 10.0 10.9 1.2 1 0 0 1 1 1 0 Clock interacting protein circadian SRP-alpha_N PF04086.13 RKO97994.1 - 0.57 10.1 4.8 0.83 9.5 4.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF1805 PF08827.11 RKO97996.1 - 0.035 14.4 0.6 0.084 13.2 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) RE_AspBHI_N PF18062.1 RKO97996.1 - 0.049 13.2 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease AspBHI N-terminal Perilipin PF03036.16 RKO97996.1 - 0.16 11.0 1.4 0.23 10.4 1.4 1.1 1 0 0 1 1 1 0 Perilipin family AMP-binding PF00501.28 RKO97997.1 - 4.9e-80 269.2 0.0 6.3e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKO97997.1 - 1.2e-14 55.0 0.8 8.6e-14 52.3 0.1 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SSB PF00436.25 RKO98001.1 - 3.7e-06 26.9 0.0 5e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 RKO98001.1 - 0.079 13.0 0.0 0.084 12.9 0.0 1.2 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain COX5A PF02284.16 RKO98002.1 - 4.1e-26 91.0 0.1 4.9e-26 90.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Sel_put PF04328.13 RKO98002.1 - 0.01 15.8 0.3 2.4 8.3 0.1 2.3 2 0 0 2 2 2 0 Selenoprotein, putative Ku_PK_bind PF08785.11 RKO98002.1 - 0.14 12.3 0.0 2.2 8.4 0.0 2.0 2 0 0 2 2 2 0 Ku C terminal domain like Hydrophobin PF01185.18 RKO98004.1 - 8e-06 26.4 8.8 1.9e-05 25.2 8.8 1.6 1 1 1 2 2 2 2 Fungal hydrophobin DnaJ PF00226.31 RKO98005.1 - 4.9e-18 65.0 0.3 7.4e-18 64.4 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 RKO98005.1 - 0.016 15.5 0.1 0.022 15.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 RKO98005.1 - 0.16 12.0 7.7 0.28 11.2 7.7 1.3 1 0 0 1 1 1 0 Glycine zipper DUF1269 PF06897.12 RKO98005.1 - 0.3 11.4 2.1 0.49 10.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1269) Asn_synthase PF00733.21 RKO98006.1 - 1e-89 301.7 1.5 4e-56 191.2 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 RKO98006.1 - 1e-37 128.8 0.0 1.8e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 RKO98006.1 - 7.4e-28 97.4 0.0 1.8e-27 96.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 RKO98006.1 - 2.6e-07 30.3 0.0 5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 RKO98006.1 - 0.045 12.9 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD synthase Acyltransferase PF01553.21 RKO98007.1 - 0.0013 18.4 0.0 0.023 14.3 0.0 2.4 1 1 0 1 1 1 1 Acyltransferase SRCR PF00530.18 RKO98007.1 - 0.044 14.3 0.0 0.073 13.6 0.0 1.3 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain DUF974 PF06159.13 RKO98008.1 - 1.5e-68 231.2 0.0 2.1e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 RKO98008.1 - 0.00012 21.6 0.0 0.004 16.6 0.0 2.7 3 0 0 3 3 3 1 TRAPP trafficking subunit Trs65 Myosin_tail_1 PF01576.19 RKO98009.1 - 9e-20 70.2 37.7 9.9e-20 70.0 37.7 1.0 1 0 0 1 1 1 1 Myosin tail Filament PF00038.21 RKO98009.1 - 0.17 11.5 27.2 0.25 10.9 27.2 1.2 1 0 0 1 1 1 0 Intermediate filament protein DASH_Hsk3 PF08227.11 RKO98009.1 - 0.22 11.9 2.2 25 5.3 0.0 3.3 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Laminin_I PF06008.14 RKO98009.1 - 0.43 10.2 23.8 0.028 14.1 7.5 2.3 1 1 1 2 2 2 0 Laminin Domain I ERM PF00769.19 RKO98009.1 - 0.48 10.2 39.6 0.08 12.8 27.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-H PF05837.12 RKO98009.1 - 0.73 10.3 32.2 0.094 13.1 13.2 2.9 1 1 2 3 3 3 0 Centromere protein H (CENP-H) Fib_alpha PF08702.10 RKO98009.1 - 0.86 9.8 17.5 0.099 12.8 11.1 2.4 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF3138 PF11336.8 RKO98009.1 - 1.3 7.5 4.9 1.7 7.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NPV_P10 PF05531.12 RKO98009.1 - 1.4 9.5 6.6 11 6.6 0.6 3.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MbeD_MobD PF04899.12 RKO98009.1 - 2.8 8.1 12.1 0.82 9.8 2.7 3.2 1 1 2 3 3 3 0 MbeD/MobD like ADIP PF11559.8 RKO98009.1 - 3.1 7.9 34.0 1.4 9.0 14.9 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1043 PF06295.12 RKO98009.1 - 3.8 7.5 17.7 1.8 8.6 6.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) FUSC PF04632.12 RKO98009.1 - 4.1 5.8 12.4 4.8 5.6 12.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family KASH_CCD PF14662.6 RKO98009.1 - 4.3 7.1 31.3 3.4 7.5 18.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 RKO98009.1 - 4.6 7.7 28.9 6.8 7.1 13.0 2.1 1 1 1 2 2 2 0 Fez1 DUF4472 PF14739.6 RKO98009.1 - 4.8 8.0 26.5 0.18 12.5 7.5 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) Prefoldin_2 PF01920.20 RKO98009.1 - 6.2 6.8 32.2 2.1 8.3 1.7 4.3 2 2 2 4 4 4 0 Prefoldin subunit Hemagglutinin PF00509.18 RKO98009.1 - 6.4 5.1 5.6 2.7 6.3 0.2 2.0 1 1 0 2 2 2 0 Haemagglutinin DHR10 PF18595.1 RKO98009.1 - 6.4 6.9 41.1 2.6 8.2 12.0 3.2 1 1 1 3 3 3 0 Designed helical repeat protein 10 domain KxDL PF10241.9 RKO98009.1 - 7.6 6.9 22.0 4.4 7.7 4.0 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein Tropomyosin_1 PF12718.7 RKO98009.1 - 8.3 6.6 33.6 3.9 7.6 22.7 2.5 1 1 1 2 2 2 0 Tropomyosin like DUF4201 PF13870.6 RKO98009.1 - 8.3 6.1 32.3 18 5.0 8.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Cyclin_N PF00134.23 RKO98012.1 - 0.0036 17.0 0.1 0.0056 16.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 RKO98012.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Cyclin EF-hand_7 PF13499.6 RKO98013.1 - 4.6e-21 75.1 1.0 5.9e-12 45.9 0.7 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 RKO98013.1 - 4.6e-20 69.6 4.8 0.0011 18.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 RKO98013.1 - 4e-15 55.4 5.9 0.00053 19.8 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 RKO98013.1 - 7e-15 53.6 7.9 0.0068 16.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 RKO98013.1 - 2.9e-12 45.5 5.0 0.0047 16.4 0.0 4.3 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 RKO98013.1 - 0.05 13.9 0.9 1.1 9.6 0.3 2.7 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 RKO98013.1 - 0.19 11.7 2.4 9.8 6.2 0.4 3.0 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Pyridoxal_deC PF00282.19 RKO98014.1 - 1.1e-17 63.9 0.0 1.7e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 RKO98014.1 - 3.2e-07 29.7 0.0 8.3e-07 28.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 RKO98014.1 - 0.00011 21.7 0.2 0.00018 20.9 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family RVT_N PF13655.6 RKO98014.1 - 0.043 14.1 0.3 0.15 12.3 0.3 1.9 1 1 0 1 1 1 0 N-terminal domain of reverse transcriptase Lon_C PF05362.13 RKO98015.1 - 2.1e-67 226.6 0.0 6.2e-67 225.1 0.0 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 RKO98015.1 - 2.7e-33 115.6 0.0 5.4e-33 114.6 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 RKO98015.1 - 6.5e-22 78.4 0.0 1.3e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.6 RKO98015.1 - 1.4e-05 24.9 0.0 2.8e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 RKO98015.1 - 2.9e-05 24.5 0.8 0.0016 18.9 0.1 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 RKO98015.1 - 4.8e-05 23.7 0.6 0.0056 17.0 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 RKO98015.1 - 5.7e-05 23.3 0.0 0.00019 21.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 RKO98015.1 - 9.1e-05 22.3 0.0 0.0004 20.2 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 RKO98015.1 - 0.00016 21.7 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 RKO98015.1 - 0.00054 19.0 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_18 PF13238.6 RKO98015.1 - 0.0075 16.8 0.0 0.021 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 RKO98015.1 - 0.015 15.7 0.0 0.045 14.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 RKO98015.1 - 0.038 14.0 0.0 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 RKO98015.1 - 0.086 12.6 0.0 0.21 11.3 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein SKI PF01202.22 RKO98015.1 - 0.092 12.9 1.9 0.13 12.4 0.1 2.1 3 0 0 3 3 2 0 Shikimate kinase NTPase_1 PF03266.15 RKO98015.1 - 0.092 12.7 0.2 0.85 9.5 0.1 2.3 1 1 1 2 2 2 0 NTPase Rad17 PF03215.15 RKO98015.1 - 0.092 12.7 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain DnaB_2 PF07261.11 RKO98015.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Replication initiation and membrane attachment TsaE PF02367.17 RKO98015.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FtsJ PF01728.19 RKO98016.1 - 1.7e-39 135.8 0.0 2e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltrans_Mon PF14314.6 RKO98016.1 - 0.036 12.1 0.0 0.042 11.9 0.0 1.1 1 0 0 1 1 1 0 Virus-capping methyltransferase MFS_1 PF07690.16 RKO98017.1 - 8.7e-20 70.9 48.9 1.8e-17 63.3 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 RKO98017.1 - 0.00014 20.9 14.4 0.00027 19.9 14.4 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MA3 PF02847.17 RKO98018.1 - 1.7e-15 57.0 0.0 4.1e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 MA3 domain MIF4G PF02854.19 RKO98018.1 - 0.0057 16.3 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 MIF4G domain SDA1 PF05285.12 RKO98018.1 - 4.3 6.7 17.9 8 5.8 17.9 1.4 1 0 0 1 1 1 0 SDA1 ERCC4 PF02732.15 RKO98019.1 - 3.9e-13 49.9 0.0 7.5e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain Ribosomal_L37e PF01907.19 RKO98020.1 - 3.9e-28 97.4 10.6 7.1e-28 96.5 10.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 RKO98020.1 - 0.004 17.1 1.2 0.0071 16.3 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.19 RKO98020.1 - 0.018 15.0 0.7 0.026 14.5 0.7 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_6 PF14599.6 RKO98020.1 - 0.07 13.2 2.7 0.12 12.4 2.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon DUF35_N PF12172.8 RKO98020.1 - 0.1 12.5 6.5 0.25 11.2 6.5 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zf-C3HC4_2 PF13923.6 RKO98020.1 - 0.75 9.7 5.1 1.3 9.0 5.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 RKO98021.1 - 1.1e-08 35.0 5.0 1.1e-05 25.6 2.7 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKO98021.1 - 7.5e-08 32.5 3.0 2e-05 24.8 0.1 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKO98021.1 - 1.1e-06 29.0 4.7 0.0024 18.5 2.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKO98021.1 - 0.0022 18.2 0.1 2.3 8.6 0.1 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 RKO98021.1 - 0.0057 16.4 2.1 1.5 8.7 1.0 2.2 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RKO98021.1 - 0.018 14.8 0.2 0.075 12.8 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf_C2H2_ZHX PF18387.1 RKO98021.1 - 0.028 14.1 0.8 1.3 8.8 0.5 2.0 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2HE PF16278.5 RKO98021.1 - 0.42 11.1 4.1 1 9.8 0.7 2.0 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FhuF_C PF11575.8 RKO98021.1 - 0.44 10.5 5.6 6 6.9 0.3 2.2 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Formyl_trans_N PF00551.19 RKO98022.1 - 6.5e-41 140.0 0.0 2e-40 138.5 0.0 1.8 1 1 0 1 1 1 1 Formyl transferase DnaJ_C PF01556.18 RKO98023.1 - 4.3e-37 127.5 0.0 5.8e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 RKO98023.1 - 2.4e-26 91.6 1.9 3.5e-26 91.1 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 RKO98023.1 - 9.6e-15 54.7 14.2 1.8e-14 53.9 14.2 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 RKO98023.1 - 7.3e-06 26.0 5.5 0.0018 18.3 0.2 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 RKO98023.1 - 0.0014 18.6 11.7 0.017 15.1 1.8 2.4 1 1 1 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Cytochrom_c3_2 PF14537.6 RKO98023.1 - 0.084 13.4 4.5 0.19 12.2 4.5 1.6 1 1 0 1 1 1 0 Cytochrome c3 DZR PF12773.7 RKO98023.1 - 0.2 11.7 9.0 0.75 9.9 9.0 1.9 1 1 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 RKO98023.1 - 0.3 10.8 7.1 3.1 7.4 0.9 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF5351 PF17302.2 RKO98023.1 - 3.3 8.0 18.6 5 7.4 0.3 4.3 4 0 0 4 4 4 0 Family of unknown function (DUF5351) Memo PF01875.17 RKO98027.1 - 1.6e-67 227.6 0.0 1.8e-67 227.4 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein zf-C2HC_2 PF13913.6 RKO98028.1 - 3.8e-19 68.1 6.5 4e-09 36.2 0.1 2.8 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 RKO98028.1 - 0.00077 19.8 3.7 0.58 10.7 0.2 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO98028.1 - 0.17 12.8 5.8 8.8 7.5 0.5 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger FYVE PF01363.21 RKO98028.1 - 0.72 10.0 3.4 18 5.6 0.4 2.2 2 0 0 2 2 2 0 FYVE zinc finger Sgf11 PF08209.11 RKO98028.1 - 1.1 8.9 5.6 0.55 9.8 1.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_11 PF16622.5 RKO98028.1 - 4.3 7.2 6.0 3 7.7 0.1 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type HSP20 PF00011.21 RKO98029.1 - 1.5e-10 41.1 0.2 1.7e-06 28.1 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family CitX PF03802.14 RKO98029.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase CS PF04969.16 RKO98029.1 - 0.033 15.2 0.0 0.073 14.1 0.0 1.6 1 0 0 1 1 1 0 CS domain TPR_2 PF07719.17 RKO98030.1 - 6.3e-05 22.8 6.5 0.22 11.7 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 RKO98030.1 - 0.00044 20.0 1.6 2.3 8.2 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 RKO98030.1 - 0.0018 18.6 1.3 2.3 8.5 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKO98030.1 - 0.005 16.8 0.9 0.46 10.6 0.0 3.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 RKO98030.1 - 0.036 14.7 0.1 0.52 11.0 0.1 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 RKO98030.1 - 0.15 12.7 3.0 67 4.4 0.0 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat zf-C2H2 PF00096.26 RKO98031.1 - 7.1e-14 51.4 1.1 3.8e-07 30.2 0.8 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 RKO98031.1 - 6.1e-09 35.9 10.2 2.1e-05 24.7 0.2 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 RKO98031.1 - 8.4e-08 32.4 5.5 2.5e-05 24.7 0.8 2.4 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 RKO98031.1 - 0.00089 19.2 0.2 0.043 13.8 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 RKO98031.1 - 0.0016 18.1 4.7 0.15 11.8 0.8 2.1 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 RKO98031.1 - 0.004 16.9 4.7 0.051 13.3 0.8 2.4 2 1 0 2 2 2 1 C2H2-type zinc-finger domain Zn_ribbon_SprT PF17283.2 RKO98031.1 - 0.0052 16.7 5.5 0.14 12.1 1.0 2.2 2 0 0 2 2 2 2 SprT-like zinc ribbon domain zf-met PF12874.7 RKO98031.1 - 0.014 15.8 0.2 0.028 14.8 0.1 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_UBZ PF18439.1 RKO98031.1 - 0.024 14.2 0.2 0.051 13.2 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 RKO98031.1 - 0.029 14.7 1.8 0.035 14.4 1.1 1.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 RKO98031.1 - 0.032 14.5 0.0 0.063 13.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 RKO98031.1 - 0.058 13.3 6.7 1.9 8.5 0.8 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type ADH_N PF08240.12 RKO98032.1 - 5.3e-27 93.9 0.2 1.1e-26 92.8 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 RKO98032.1 - 5e-14 52.4 0.1 5e-11 42.7 0.0 2.4 1 1 0 2 2 2 2 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 RKO98032.1 - 0.0005 19.6 0.2 0.0021 17.6 0.0 2.0 3 0 0 3 3 3 1 Glucose dehydrogenase C-terminus VWA_2 PF13519.6 RKO98034.1 - 2e-08 34.8 0.0 0.0075 16.9 0.0 2.8 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA PF00092.28 RKO98034.1 - 0.013 15.8 0.0 3.6 7.8 0.0 2.7 2 1 0 2 2 2 0 von Willebrand factor type A domain Rad52_Rad22 PF04098.15 RKO98035.1 - 8.5e-51 171.9 0.0 1e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein BCS1_N PF08740.11 RKO98036.1 - 1.3e-33 116.6 0.0 1.8e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 RKO98036.1 - 2.5e-15 57.1 0.0 1.1e-14 55.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 RKO98036.1 - 0.00032 21.1 0.2 0.0018 18.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 RKO98036.1 - 0.00037 20.1 0.0 0.016 14.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 RKO98036.1 - 0.0019 18.2 0.0 0.0045 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 RKO98036.1 - 0.0041 17.3 0.0 0.0087 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 RKO98036.1 - 0.0081 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_6 PF12774.7 RKO98036.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_30 PF13604.6 RKO98036.1 - 0.03 14.0 0.3 0.44 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 RKO98036.1 - 0.045 14.3 0.0 0.074 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 RKO98036.1 - 0.067 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 RKO98036.1 - 0.068 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 RKO98036.1 - 0.093 13.0 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 RKO98036.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RKO98036.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 RKO98036.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PPV_E1_C PF00519.17 RKO98036.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_24 PF13479.6 RKO98036.1 - 0.16 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 RKO98036.1 - 0.18 11.7 0.1 0.34 10.8 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Gemini_AC4_5 PF04807.12 RKO98037.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region SDA1 PF05285.12 RKO98039.1 - 0.96 8.8 9.0 1.1 8.6 9.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 RKO98039.1 - 4.3 6.6 7.9 4.8 6.4 7.9 1.1 1 0 0 1 1 1 0 BUD22 Tropomyosin_1 PF12718.7 RKO98040.1 - 7.5e-22 78.0 42.6 8.8e-22 77.8 42.6 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 RKO98040.1 - 8.8e-09 35.1 42.1 3.3e-05 23.4 26.8 2.4 1 1 1 2 2 2 2 Tropomyosin DHR10 PF18595.1 RKO98040.1 - 0.031 14.3 48.1 0.059 13.4 20.5 3.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain GAS PF13851.6 RKO98040.1 - 0.051 12.9 38.8 1.1 8.6 38.8 2.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DRTGG PF07085.12 RKO98040.1 - 0.11 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 DRTGG domain Dynamitin PF04912.14 RKO98040.1 - 0.55 9.5 28.5 0.87 8.8 28.5 1.4 1 1 0 1 1 1 0 Dynamitin Laminin_II PF06009.12 RKO98040.1 - 0.62 10.1 20.9 0.28 11.2 1.7 2.4 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 RKO98040.1 - 1.4 9.0 39.3 3.2 7.8 17.3 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 RKO98040.1 - 1.4 8.9 42.2 3.6 7.6 4.1 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FapA PF03961.13 RKO98040.1 - 1.8 7.0 26.6 0.44 9.1 14.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF1664 PF07889.12 RKO98040.1 - 1.9 8.6 15.8 2 8.5 4.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.11 RKO98040.1 - 2 8.2 14.6 2.2 8.1 5.9 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fez1 PF06818.15 RKO98040.1 - 2.1 8.8 34.4 1.2e+02 3.0 34.1 2.0 1 1 0 1 1 1 0 Fez1 FemAB PF02388.16 RKO98040.1 - 2.1 7.2 27.4 0.67 8.8 9.7 2.0 1 1 1 2 2 2 0 FemAB family Noelin-1 PF12308.8 RKO98040.1 - 2.1 8.4 13.3 2.2 8.3 2.3 2.4 2 1 0 2 2 2 0 Neurogenesis glycoprotein DUF4200 PF13863.6 RKO98040.1 - 2.3 8.6 43.1 1.3 9.5 25.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Vps5 PF09325.10 RKO98040.1 - 2.3 7.7 25.5 3.7 7.0 7.7 2.4 1 1 0 2 2 2 0 Vps5 C terminal like UPF0242 PF06785.11 RKO98040.1 - 3.3 7.8 39.6 39 4.3 19.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 RKO98040.1 - 3.5 7.8 19.4 2.2 8.5 6.5 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 RKO98040.1 - 3.7 4.9 36.6 5.3 4.4 36.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 RKO98040.1 - 4.2 7.9 11.2 1.4 9.4 1.6 3.1 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein BST2 PF16716.5 RKO98040.1 - 4.3 8.0 31.5 2.9 8.6 14.2 2.6 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 Sec34 PF04136.15 RKO98040.1 - 5.1 7.0 16.3 3 7.7 2.7 2.5 1 1 1 3 3 3 0 Sec34-like family ADIP PF11559.8 RKO98040.1 - 5.6 7.0 33.3 2 8.5 5.4 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding CREPT PF16566.5 RKO98040.1 - 6.2 7.0 28.0 0.29 11.3 12.8 2.3 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DASH_Spc19 PF08287.11 RKO98040.1 - 7.2 6.5 35.6 13 5.7 3.2 2.8 1 1 1 2 2 2 0 Spc19 Baculo_PEP_C PF04513.12 RKO98040.1 - 7.3 6.6 10.0 13 5.8 0.1 2.7 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMCO5 PF14992.6 RKO98040.1 - 7.4 6.1 30.7 1.2e+02 2.0 30.7 1.9 1 1 0 1 1 1 0 TMCO5 family T3SS_basalb_I PF17001.5 RKO98040.1 - 7.7 7.2 12.9 3.3 8.4 2.1 2.6 1 1 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI DUF948 PF06103.11 RKO98040.1 - 7.8 6.8 8.0 28 5.0 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cluap1 PF10234.9 RKO98040.1 - 9.7 5.5 31.7 0.38 10.1 10.1 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 ERM PF00769.19 RKO98040.1 - 9.9 5.9 50.2 0.068 13.0 6.7 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3067 PF11267.8 RKO98041.1 - 0.038 14.6 0.1 30 5.3 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3067) Myb_DNA-binding PF00249.31 RKO98042.1 - 1.4e-39 134.0 6.5 4.1e-15 55.7 2.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 RKO98042.1 - 1.6e-30 105.1 0.0 8.2e-11 42.0 0.0 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 RKO98042.1 - 0.0035 17.4 2.0 0.8 9.8 0.0 3.0 1 1 2 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.6 RKO98042.1 - 0.14 12.5 4.1 10 6.5 0.9 3.7 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain zf-H2C2_2 PF13465.6 RKO98043.1 - 7.2e-13 48.3 5.5 4e-06 27.0 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKO98043.1 - 2.9e-05 24.3 22.5 0.0025 18.2 3.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zinc_ribbon_9 PF14369.6 RKO98043.1 - 0.00025 21.2 2.0 0.032 14.5 0.3 2.3 2 0 0 2 2 2 1 zinc-ribbon zf-C2H2_4 PF13894.6 RKO98043.1 - 0.00089 19.9 22.0 0.0088 16.8 3.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger ADK_lid PF05191.14 RKO98043.1 - 0.0076 16.2 5.1 1.7 8.7 0.3 2.9 2 1 1 3 3 3 2 Adenylate kinase, active site lid zf-C2H2_jaz PF12171.8 RKO98043.1 - 0.03 14.6 9.4 0.069 13.5 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 RKO98043.1 - 0.032 14.2 13.0 1.1 9.3 1.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-ISL3 PF14690.6 RKO98043.1 - 0.037 14.7 0.4 0.037 14.7 0.4 2.4 1 1 1 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_11 PF16622.5 RKO98043.1 - 0.05 13.4 2.7 0.05 13.4 2.7 2.4 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 RKO98043.1 - 0.053 13.9 0.4 0.053 13.9 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zinc-ribbons_6 PF07191.12 RKO98043.1 - 0.057 13.4 3.7 0.22 11.5 3.7 2.0 1 1 0 1 1 1 0 zinc-ribbons FYDLN_acid PF09538.10 RKO98043.1 - 0.15 12.8 1.2 2.2 9.0 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) TRAF6_Z2 PF18048.1 RKO98043.1 - 0.15 12.2 3.5 4.5 7.4 0.5 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-UDP PF14569.6 RKO98043.1 - 0.46 10.6 4.2 3.1 8.0 0.4 2.1 1 1 1 2 2 2 0 Zinc-binding RING-finger Zn_ribbon_SprT PF17283.2 RKO98043.1 - 0.66 9.9 9.6 2.2 8.2 1.9 2.6 2 1 0 2 2 2 0 SprT-like zinc ribbon domain Prok-RING_1 PF14446.6 RKO98043.1 - 0.74 9.8 9.8 7.6 6.6 0.3 3.1 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Zn_Tnp_IS1595 PF12760.7 RKO98043.1 - 5.9 6.9 11.3 5.1 7.1 1.9 2.5 1 1 0 2 2 2 0 Transposase zinc-ribbon domain Ribosomal_S5 PF00333.20 RKO98045.1 - 5.2e-29 100.0 1.1 5.2e-29 100.0 1.1 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 RKO98045.1 - 1.2e-23 82.3 0.0 1.9e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 RKO98045.1 - 2.9 8.5 12.1 6.3 7.4 12.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Tubulin PF00091.25 RKO98046.1 - 4.5e-58 196.7 0.0 6.2e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 RKO98046.1 - 2.1e-18 66.7 0.0 3.2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 RKO98046.1 - 0.029 13.5 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Tubulin like DUF1681 PF07933.14 RKO98047.1 - 1.1e-46 158.2 0.0 1.2e-46 158.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) AMP-binding PF00501.28 RKO98048.1 - 4.6e-85 285.7 0.1 5.9e-85 285.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 RKO98048.1 - 2.5e-12 47.6 0.1 7.6e-12 46.0 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aph-1 PF06105.12 RKO98050.1 - 1.3e-50 171.9 17.1 1.6e-50 171.7 17.1 1.0 1 0 0 1 1 1 1 Aph-1 protein V-SNARE_C PF12352.8 RKO98052.1 - 5.4e-08 33.0 1.3 5.4e-08 33.0 1.3 2.6 3 2 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 RKO98052.1 - 5.2e-05 23.1 2.2 5.2e-05 23.1 2.2 2.1 2 0 0 2 2 2 1 Sec20 DUF5089 PF17002.5 RKO98052.1 - 0.017 15.0 4.0 0.017 15.0 4.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5089) GATase PF00117.28 RKO98052.1 - 0.053 13.3 0.1 0.31 10.8 0.0 2.0 1 1 1 2 2 2 0 Glutamine amidotransferase class-I Fusion_gly PF00523.18 RKO98052.1 - 0.077 11.2 5.0 0.051 11.8 1.8 1.9 2 0 0 2 2 2 0 Fusion glycoprotein F0 ING PF12998.7 RKO98052.1 - 2.2 8.9 8.7 3.3 8.3 0.6 3.2 2 1 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding SH3_9 PF14604.6 RKO98053.1 - 2.8e-05 23.9 0.0 5.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 RKO98053.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain LAP1C PF05609.12 RKO98053.1 - 0.0052 15.9 1.7 0.0074 15.4 1.7 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) SH3_2 PF07653.17 RKO98053.1 - 0.031 13.9 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain Amnionless PF14828.6 RKO98053.1 - 0.084 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Amnionless DUF4381 PF14316.6 RKO98053.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Apt1 PF10351.9 RKO98053.1 - 2.6 6.8 6.5 3.7 6.3 6.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 RKO98055.1 - 2.8e-17 63.2 23.2 2.8e-17 63.2 23.2 3.9 4 1 0 4 4 4 1 BUD22 eIF-5a PF01287.20 RKO98056.1 - 6.5e-27 93.4 0.2 9.5e-27 92.9 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 RKO98056.1 - 0.0013 18.7 0.1 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EF-hand_4 PF12763.7 RKO98057.1 - 3e-05 23.9 0.0 4.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand TMF_TATA_bd PF12325.8 RKO98057.1 - 0.0059 16.8 0.3 0.014 15.6 0.0 1.7 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Dpy-30 PF05186.13 RKO98058.1 - 0.00021 20.9 0.9 0.22 11.2 0.1 2.4 2 0 0 2 2 2 2 Dpy-30 motif MMPL PF03176.15 RKO98058.1 - 4 6.3 9.5 5 6.0 9.5 1.2 1 0 0 1 1 1 0 MMPL family MITF_TFEB_C_3_N PF15951.5 RKO98058.1 - 6.2 7.4 10.1 0.62 10.7 4.6 2.0 2 0 0 2 2 2 0 MITF/TFEB/TFEC/TFE3 N-terminus Serglycin PF04360.12 RKO98059.1 - 0.7 9.8 7.4 1 9.3 7.4 1.2 1 0 0 1 1 1 0 Serglycin RhoGAP PF00620.27 RKO98060.1 - 3.5e-11 43.2 0.0 2.5e-10 40.4 0.0 2.1 1 1 0 1 1 1 1 RhoGAP domain NDUF_B12 PF08122.12 RKO98060.1 - 4.2e-11 42.7 0.6 9.9e-11 41.5 0.6 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Exo_endo_phos PF03372.23 RKO98060.1 - 3.4e-09 36.5 0.1 6.6e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RNA_pol_Rpb6 PF01192.22 RKO98061.1 - 3.3e-16 58.9 0.1 4.6e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 CAF1 PF04857.20 RKO98062.1 - 1.9e-76 257.3 0.0 3.5e-76 256.4 0.0 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease Sas10_Utp3 PF04000.15 RKO98063.1 - 3e-09 37.4 0.1 4.7e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Sas10/Utp3/C1D family TraD PF06412.11 RKO98063.1 - 0.077 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TraD Pox_A_type_inc PF04508.12 RKO98065.1 - 5.1 7.1 7.8 4.5 7.3 0.7 4.0 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat ANAPC4_WD40 PF12894.7 RKO98066.1 - 3e-12 46.7 3.1 0.018 15.3 0.0 5.5 3 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 RKO98066.1 - 8.3e-06 26.5 4.4 9.8 7.2 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat PD40 PF07676.12 RKO98066.1 - 0.0057 16.6 0.3 2.5 8.2 0.0 3.2 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat DUF745 PF05335.13 RKO98066.1 - 2.9 7.6 9.8 6.6 6.4 9.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF745) MutS_V PF00488.21 RKO98067.1 - 1.2e-62 211.3 0.0 1.5e-61 207.7 0.0 2.9 4 0 0 4 4 4 1 MutS domain V MutS_III PF05192.18 RKO98067.1 - 3.4e-31 109.0 1.6 4.2e-31 108.7 0.4 1.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 RKO98067.1 - 6.2e-26 90.9 0.0 1.4e-25 89.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 RKO98067.1 - 4.7e-09 36.6 0.3 1.4e-08 35.1 0.3 1.9 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 RKO98067.1 - 9.2e-08 32.3 0.0 2.8e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV PPR PF01535.20 RKO98068.1 - 0.075 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 PPR repeat PPR_2 PF13041.6 RKO98068.1 - 0.078 13.2 0.1 0.36 11.0 0.0 2.0 1 1 1 2 2 2 0 PPR repeat family Aa_trans PF01490.18 RKO98069.1 - 4.4e-78 262.8 33.4 5.1e-78 262.6 33.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aminotran_1_2 PF00155.21 RKO98070.1 - 6.9e-55 186.7 0.0 8.3e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 RKO98070.1 - 1.1e-06 28.1 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 RKO98070.1 - 0.0073 15.7 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 RKO98070.1 - 0.0095 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 RKO98070.1 - 0.11 11.0 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF4874 PF16173.5 RKO98072.1 - 1.7e-06 27.8 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4874) PRCC PF10253.9 RKO98072.1 - 0.067 14.0 4.9 0.1 13.4 4.9 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF4832 PF16116.5 RKO98072.1 - 0.079 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) MMS1_N PF10433.9 RKO98073.1 - 4.4e-124 414.8 0.0 2.7e-123 412.2 0.0 2.4 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 RKO98073.1 - 3.2e-73 246.9 0.0 1.6e-71 241.3 0.0 2.8 3 1 0 3 3 3 1 CPSF A subunit region Ras PF00071.22 RKO98074.1 - 5e-46 156.3 0.0 5.7e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 RKO98074.1 - 1.2e-29 102.9 0.0 1.6e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 RKO98074.1 - 7e-13 48.4 0.0 8.1e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 RKO98074.1 - 2.1e-05 24.1 0.1 0.00043 19.9 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 RKO98074.1 - 3.7e-05 23.2 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 RKO98074.1 - 7.3e-05 22.8 0.0 9.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 RKO98074.1 - 0.0046 16.9 0.0 0.67 9.8 0.0 2.4 2 1 1 3 3 3 1 RsgA GTPase SRPRB PF09439.10 RKO98074.1 - 0.0088 15.5 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 RKO98074.1 - 0.03 14.1 0.0 0.23 11.2 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein GAPES3 PF17154.4 RKO98074.1 - 0.16 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain HIG_1_N PF04588.13 RKO98075.1 - 0.0019 18.4 0.6 0.043 14.0 0.2 2.3 2 0 0 2 2 2 1 Hypoxia induced protein conserved region ArsP_1 PF03773.13 RKO98075.1 - 0.073 12.2 0.0 0.091 11.9 0.0 1.1 1 0 0 1 1 1 0 Predicted permease ENOD93 PF03386.14 RKO98075.1 - 0.074 12.9 0.1 0.074 12.9 0.1 2.0 3 0 0 3 3 3 0 Early nodulin 93 ENOD93 protein Peptidase_S9 PF00326.21 RKO98076.1 - 1.6e-06 27.8 0.0 3.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 RKO98076.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 RKO98076.1 - 0.014 14.7 0.0 0.079 12.2 0.0 2.1 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Kri1_C PF12936.7 RKO98077.1 - 1.7e-17 63.4 0.1 1.7e-17 63.4 0.1 3.1 4 1 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 RKO98077.1 - 1.9e-17 63.7 6.8 1.9e-17 63.7 6.8 4.8 4 1 1 5 5 5 1 KRI1-like family HATPase_c PF02518.26 RKO98078.1 - 2.9e-13 50.3 0.1 3.5e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 RKO98078.1 - 2.8e-12 46.6 0.3 3.8e-12 46.2 0.3 1.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2623 PF11115.8 RKO98079.1 - 0.037 14.1 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2623) KapB PF08810.10 RKO98079.1 - 0.37 11.0 1.1 1.2 9.3 0.0 2.4 3 0 0 3 3 3 0 Kinase associated protein B Shugoshin_N PF07558.11 RKO98080.1 - 0.012 15.4 2.2 0.026 14.4 2.2 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Csm2_III-A PF03750.13 RKO98080.1 - 0.017 16.0 0.6 0.043 14.7 0.6 1.6 1 0 0 1 1 1 0 Csm2 Type III-A APG6_N PF17675.1 RKO98080.1 - 4.5 7.8 11.8 0.25 11.8 3.2 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region Spc24 PF08286.11 RKO98080.1 - 4.8 7.5 7.9 0.25 11.6 0.9 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Pkinase PF00069.25 RKO98081.1 - 1.2e-67 228.0 0.0 1.5e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98081.1 - 3.6e-25 88.7 0.0 6.2e-25 88.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 RKO98081.1 - 6.5e-06 25.7 0.0 0.00023 20.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RKO98081.1 - 0.00078 19.4 0.4 0.02 14.8 0.2 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 RKO98081.1 - 0.0075 15.9 0.1 0.012 15.3 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 RKO98081.1 - 0.01 15.2 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Scm3 PF10384.9 RKO98082.1 - 4.5e-09 35.9 4.3 5.4e-08 32.5 4.3 2.4 1 1 0 1 1 1 1 Centromere protein Scm3 rRNA_processing PF08524.11 RKO98083.1 - 1.5e-08 34.8 15.4 1.5e-08 34.8 15.4 2.8 1 1 1 2 2 2 2 rRNA processing Phage_Gp23 PF10669.9 RKO98083.1 - 3.1 8.1 6.3 6.2 7.2 6.3 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MS_channel PF00924.18 RKO98084.1 - 1.1e-19 70.9 0.1 1.3e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 RKO98084.1 - 2.5e-05 23.5 0.2 0.00013 21.2 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 RKO98084.1 - 2.9e-05 23.6 0.0 9.7e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 RKO98084.1 - 0.00056 19.3 0.1 0.0026 17.2 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 RKO98084.1 - 0.0013 19.1 0.2 0.0049 17.3 0.2 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 RKO98084.1 - 0.045 13.6 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair PMT PF02366.18 RKO98086.1 - 1.2e-77 260.8 19.9 1.2e-77 260.8 19.9 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 RKO98086.1 - 3.1e-53 180.3 14.1 3.1e-53 180.3 14.1 2.4 3 1 0 4 4 4 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 RKO98086.1 - 1.3e-27 96.8 0.0 2e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 MIR domain PsbT PF01405.17 RKO98086.1 - 0.079 12.8 0.1 0.079 12.8 0.1 3.7 4 0 0 4 4 4 0 Photosystem II reaction centre T protein His_biosynth PF00977.21 RKO98087.1 - 3.2e-19 69.3 0.0 4.5e-17 62.3 0.0 2.2 2 0 0 2 2 2 2 Histidine biosynthesis protein DEAD PF00270.29 RKO98088.1 - 8.3e-48 162.5 0.0 1.2e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 RKO98088.1 - 5e-31 107.3 0.0 2.3e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98088.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 RKO98088.1 - 0.037 12.8 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 RKO98088.1 - 0.22 11.8 0.2 2 8.7 0.2 2.2 1 1 0 1 1 1 0 AAA domain UTP25 PF06862.12 RKO98088.1 - 0.25 10.1 0.0 6.5 5.4 0.0 2.2 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Orn_Arg_deC_N PF02784.16 RKO98090.1 - 2e-77 259.9 0.0 2.5e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 RKO98090.1 - 7.4e-20 71.0 0.0 9.2e-20 70.7 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SNF2_N PF00176.23 RKO98091.1 - 3.3e-71 239.8 1.7 5.8e-71 239.0 0.2 2.1 2 1 1 3 3 3 1 SNF2 family N-terminal domain SLIDE PF09111.10 RKO98091.1 - 9.1e-40 135.2 0.6 3.1e-39 133.5 0.6 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.11 RKO98091.1 - 2.6e-22 79.7 1.0 2.6e-22 79.7 1.0 3.1 3 0 0 3 3 3 1 HAND Helicase_C PF00271.31 RKO98091.1 - 4.4e-18 65.6 0.0 2.4e-17 63.3 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 RKO98091.1 - 3.9e-07 30.2 0.0 2.7e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 RKO98091.1 - 0.014 15.0 0.0 0.053 13.2 0.0 2.1 2 1 0 2 2 2 0 SWI2/SNF2 ATPase Adap_comp_sub PF00928.21 RKO98092.1 - 1.2e-70 237.9 0.0 1.5e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 RKO98092.1 - 0.0026 17.2 0.1 0.0079 15.7 0.0 1.7 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.20 RKO98092.1 - 0.0035 17.3 0.2 0.0069 16.3 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyl-CoA_dh_1 PF00441.24 RKO98094.1 - 1.9e-45 154.8 1.1 2.9e-45 154.1 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 RKO98094.1 - 3.3e-28 98.6 1.1 8.9e-28 97.2 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 RKO98094.1 - 5.9e-24 84.1 0.0 1.1e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 RKO98094.1 - 1.5e-20 73.9 2.3 2.6e-20 73.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Homeodomain PF00046.29 RKO98095.1 - 4.3e-13 48.9 0.3 8.1e-13 48.0 0.3 1.5 1 0 0 1 1 1 1 Homeodomain MRP-L20 PF12824.7 RKO98095.1 - 1.2e-05 25.5 7.0 3.5e-05 24.0 7.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Homeobox_KN PF05920.11 RKO98095.1 - 0.045 13.7 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain DUF4211 PF13926.6 RKO98097.1 - 5e-24 85.0 0.0 9.6e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) Piwi PF02171.17 RKO98098.1 - 4.9e-79 265.7 0.0 7.9e-79 265.0 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 RKO98098.1 - 4.5e-15 56.5 0.0 8.4e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 RKO98098.1 - 1.8e-14 53.1 0.0 3.9e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 RKO98098.1 - 7.3e-13 48.5 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 RKO98098.1 - 6.5e-05 23.1 0.0 0.00016 21.9 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 RKO98098.1 - 0.00012 22.3 0.0 0.00051 20.3 0.0 2.2 2 0 0 2 2 2 1 Argonaute linker 2 domain tRNA-synt_2b PF00587.25 RKO98099.1 - 2.5e-30 105.8 0.0 4.5e-30 104.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 RKO98099.1 - 1.1e-16 60.7 0.1 2.7e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 RKO98099.1 - 9.7e-13 48.0 0.0 1.9e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 RKO98099.1 - 1.1e-10 41.4 0.0 5e-10 39.3 0.0 2.1 3 0 0 3 3 3 1 TGS domain Pkinase PF00069.25 RKO98100.1 - 2.3e-56 191.1 0.0 1.2e-37 129.7 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98100.1 - 2.4e-23 82.8 0.4 1.6e-16 60.3 0.1 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 RKO98100.1 - 0.00023 20.6 0.4 0.0005 19.5 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 RKO98100.1 - 0.00025 21.0 3.1 0.0054 16.7 0.5 2.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 RKO98100.1 - 0.018 14.7 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 RKO98100.1 - 0.055 12.2 0.1 0.11 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase DUF1003 PF06210.11 RKO98100.1 - 1.2 9.2 3.1 2.9 8.0 3.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Ribosomal_60s PF00428.19 RKO98100.1 - 8.2 7.1 7.7 14 6.4 6.9 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Rhodanese PF00581.20 RKO98101.1 - 1.2e-16 61.1 0.0 1.5e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain PI-PLC-X PF00388.19 RKO98103.1 - 1e-56 190.6 0.0 1.6e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 RKO98103.1 - 1.6e-25 89.7 0.0 3.5e-25 88.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain PH_12 PF16457.5 RKO98103.1 - 2.1e-06 28.3 0.0 5.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain C2 PF00168.30 RKO98103.1 - 0.0009 19.5 0.0 0.01 16.1 0.0 2.5 3 0 0 3 3 3 1 C2 domain EF-hand_like PF09279.11 RKO98103.1 - 0.0012 19.3 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like PH_14 PF17787.1 RKO98103.1 - 0.24 11.3 0.0 0.58 10.0 0.0 1.7 1 1 0 1 1 1 0 PH domain ARPC4 PF05856.12 RKO98104.1 - 1.9e-80 268.3 5.7 2.1e-80 268.2 5.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF4255 PF14065.6 RKO98104.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4255) GPS2_interact PF15784.5 RKO98104.1 - 0.076 13.5 0.9 14 6.2 0.0 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain SCP2 PF02036.17 RKO98105.1 - 4.1e-05 24.0 0.0 5.7e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 SCP-2 sterol transfer family PP28 PF10252.9 RKO98106.1 - 2e-20 73.0 14.6 3.2e-20 72.4 13.9 1.7 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 AF-4 PF05110.13 RKO98106.1 - 0.055 11.6 10.6 0.074 11.1 10.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Nop53 PF07767.11 RKO98106.1 - 7.2 5.9 18.3 7.4 5.8 18.1 1.3 1 1 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Peptidase_M49 PF03571.15 RKO98107.1 - 1.2e-196 654.4 0.0 1.4e-196 654.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Gemini_AC4_5_2 PF08464.10 RKO98108.1 - 0.016 15.2 1.1 0.039 13.9 1.1 1.7 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region NOG1 PF06858.14 RKO98108.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Abhydrolase_3 PF07859.13 RKO98109.1 - 3.5e-13 49.9 1.6 4.1e-12 46.4 1.6 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 RKO98109.1 - 2e-06 27.4 0.0 4.3e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 RKO98109.1 - 3e-05 23.1 0.1 5.7e-05 22.2 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family Hydrolase_4 PF12146.8 RKO98109.1 - 0.011 15.0 0.3 3.2 6.9 0.2 2.7 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 RKO98109.1 - 0.059 13.1 0.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Urm1 PF09138.11 RKO98111.1 - 3.9e-32 110.5 0.0 4.6e-32 110.2 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 RKO98111.1 - 0.00026 21.5 0.0 0.00037 21.1 0.0 1.3 1 0 0 1 1 1 1 ThiS family Pex2_Pex12 PF04757.14 RKO98112.1 - 7e-21 74.9 9.2 1.6e-20 73.7 9.2 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_5 PF14634.6 RKO98112.1 - 2.9e-05 23.9 5.2 4.7e-05 23.3 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 RKO98112.1 - 6.6e-05 23.2 6.2 0.00011 22.4 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 RKO98112.1 - 0.0001 22.1 6.3 0.00016 21.4 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 RKO98112.1 - 0.00011 22.0 6.7 0.00018 21.3 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 RKO98112.1 - 0.00051 20.0 5.8 0.001 19.0 5.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 RKO98112.1 - 0.00073 19.3 5.9 0.0016 18.3 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 RKO98112.1 - 0.0011 19.1 7.7 0.0034 17.5 7.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 RKO98112.1 - 0.25 11.1 2.9 0.5 10.2 2.9 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 RKO98112.1 - 0.29 11.4 2.7 0.56 10.5 2.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain ABC_tran_CTD PF16326.5 RKO98113.1 - 0.0081 16.4 1.2 0.0081 16.4 1.2 4.4 3 2 3 6 6 6 1 ABC transporter C-terminal domain Flavi_capsid PF01003.19 RKO98113.1 - 0.048 13.4 0.2 0.76 9.6 0.0 2.5 2 1 0 2 2 2 0 Flavivirus capsid protein C DDE_Tnp_1_6 PF13751.6 RKO98113.1 - 0.068 13.4 0.1 0.068 13.4 0.1 2.2 3 0 0 3 3 3 0 Transposase DDE domain FlaC_arch PF05377.11 RKO98113.1 - 0.068 13.6 11.8 0.35 11.3 1.0 5.1 5 3 3 8 8 8 0 Flagella accessory protein C (FlaC) YkuI_C PF10388.9 RKO98113.1 - 0.12 12.2 2.0 0.16 11.7 0.3 2.0 2 1 0 2 2 2 0 EAL-domain associated signalling protein domain AbiJ_NTD4 PF18863.1 RKO98113.1 - 0.48 10.9 4.1 0.39 11.2 2.2 1.9 1 1 1 2 2 2 0 AbiJ N-terminal domain 4 CAP_GLY PF01302.25 RKO98114.1 - 1.6e-22 79.3 0.2 1.7e-22 79.2 0.2 1.0 1 0 0 1 1 1 1 CAP-Gly domain Importin_rep PF18773.1 RKO98115.1 - 0.00015 21.4 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Importin 13 repeat Xpo1 PF08389.12 RKO98115.1 - 0.00059 19.9 2.7 0.0041 17.2 0.1 3.4 3 0 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.6 RKO98117.1 - 3e-33 114.1 0.5 2.5e-17 63.1 0.0 3.8 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 RKO98117.1 - 5e-28 94.9 0.3 6.2e-07 29.5 0.0 6.6 6 0 0 6 6 6 6 PBS lyase HEAT-like repeat HEAT PF02985.22 RKO98117.1 - 1.6e-14 52.8 0.7 0.016 15.4 0.0 5.1 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 RKO98117.1 - 1.2e-10 41.6 1.3 0.29 11.7 0.0 5.0 5 0 0 5 5 5 3 HEAT-like repeat Arm PF00514.23 RKO98117.1 - 1.1e-05 25.3 0.2 0.47 10.6 0.0 3.9 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 RKO98117.1 - 0.001 19.1 0.0 5.3 7.1 0.0 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 RKO98117.1 - 0.0022 18.3 0.2 1.2 9.5 0.0 3.7 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Vitellogenin_N PF01347.22 RKO98117.1 - 0.11 10.8 0.0 4.1 5.7 0.0 2.6 2 1 1 3 3 3 0 Lipoprotein amino terminal region ETC_C1_NDUFA4 PF04800.12 RKO98118.1 - 4.1e-36 123.1 0.8 4.7e-36 122.9 0.8 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 RKO98118.1 - 0.042 14.0 0.1 0.092 12.9 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) DUF2280 PF10045.9 RKO98118.1 - 0.057 13.7 0.1 0.47 10.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Cu_amine_oxidN2 PF02727.16 RKO98118.1 - 0.14 12.4 0.1 0.42 10.9 0.0 1.8 2 1 0 2 2 2 0 Copper amine oxidase, N2 domain NYD-SP28 PF14772.6 RKO98119.1 - 5.5e-16 58.5 7.5 5.5e-16 58.5 7.5 5.1 2 2 3 5 5 5 1 Sperm tail CCCAP PF15964.5 RKO98119.1 - 0.00036 19.0 32.8 0.0005 18.5 32.8 1.2 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family Baculo_PEP_C PF04513.12 RKO98119.1 - 3.1 7.8 12.2 4.6 7.3 0.3 3.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NYD-SP28_assoc PF14775.6 RKO98119.1 - 6.9 6.9 17.9 0.16 12.1 1.0 4.1 4 0 0 4 4 4 0 Sperm tail C-terminal domain zf-C2H2_aberr PF17017.5 RKO98120.1 - 0.00047 20.4 2.3 0.00083 19.5 0.1 2.2 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 RKO98120.1 - 0.0024 18.6 5.7 0.87 10.6 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 RKO98120.1 - 0.0047 17.3 2.7 2.4 8.8 0.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type DUF382 PF04037.13 RKO98121.1 - 5.5e-52 175.2 0.0 7e-52 174.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 RKO98121.1 - 3.7e-21 74.7 3.7 7.7e-21 73.7 3.7 1.6 1 0 0 1 1 1 1 PSP NTP_transf_2 PF01909.23 RKO98122.1 - 4e-12 46.3 0.0 8.9e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 RKO98122.1 - 0.0009 19.4 0.4 0.0024 18.0 0.4 1.8 1 1 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 RKO98122.1 - 0.016 15.3 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Aminotran_3 PF00202.21 RKO98123.1 - 1.4e-108 363.2 0.0 1.6e-108 362.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 RKO98123.1 - 0.1 11.7 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II DUF4200 PF13863.6 RKO98124.1 - 5.9e-25 88.0 22.5 1.8e-22 80.0 13.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.8 RKO98124.1 - 0.0039 17.1 13.6 0.012 15.6 0.8 3.4 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding CHASE7 PF17151.4 RKO98124.1 - 0.12 11.9 6.9 0.077 12.6 4.5 2.0 1 1 0 1 1 1 0 Periplasmic sensor domain Sigma_reg_C PF13791.6 RKO98124.1 - 0.13 12.5 4.3 0.078 13.2 2.0 1.8 2 0 0 2 2 2 0 Sigma factor regulator C-terminal Spc7 PF08317.11 RKO98124.1 - 0.14 11.0 22.7 0.3 9.9 5.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 RKO98124.1 - 0.35 10.2 14.9 0.037 13.4 2.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 RKO98124.1 - 0.47 10.6 17.0 0.093 12.9 3.1 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family CRR7 PF12095.8 RKO98124.1 - 0.58 10.6 9.4 1.1 9.8 1.9 3.5 2 1 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF1664 PF07889.12 RKO98124.1 - 0.71 9.9 14.9 1.5 8.8 0.8 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) COG5 PF10392.9 RKO98124.1 - 2.8 8.1 14.3 0.15 12.3 7.4 2.1 2 1 0 2 2 2 0 Golgi transport complex subunit 5 HrpB7 PF09486.10 RKO98124.1 - 9.4 6.6 23.4 0.35 11.2 7.5 2.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Methyltransf_23 PF13489.6 RKO98126.1 - 6.7e-17 61.8 0.0 1.2e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 RKO98126.1 - 8.9e-17 61.7 0.0 4.1e-16 59.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 RKO98126.1 - 2.3e-14 53.9 0.0 5.6e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 RKO98126.1 - 3.3e-11 43.7 0.0 6.8e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 RKO98126.1 - 4.9e-09 36.1 0.0 7.6e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 RKO98126.1 - 0.0065 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 RKO98126.1 - 0.04 14.9 0.0 0.24 12.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 RKO98126.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Tellurite resistance protein TehB CheR PF01739.18 RKO98126.1 - 0.056 12.9 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain NNMT_PNMT_TEMT PF01234.17 RKO98126.1 - 0.15 11.2 0.0 0.48 9.6 0.0 1.8 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family DAD PF02109.16 RKO98127.1 - 7.3e-34 116.4 0.4 9.2e-34 116.0 0.4 1.1 1 0 0 1 1 1 1 DAD family DUF4389 PF14333.6 RKO98127.1 - 0.035 14.0 0.4 0.064 13.2 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) TPR_12 PF13424.6 RKO98128.1 - 5.9e-07 29.7 6.1 0.00063 20.0 0.2 4.5 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 RKO98128.1 - 6.8e-06 25.8 3.6 0.037 14.1 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 RKO98128.1 - 1.5e-05 24.6 0.2 0.04 13.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 RKO98128.1 - 3e-05 23.7 0.2 0.011 15.5 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 RKO98128.1 - 0.0016 18.4 2.4 0.68 10.2 0.2 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat SUIM_assoc PF16619.5 RKO98128.1 - 0.84 9.8 5.8 5.3 7.2 5.8 2.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DNA_pol_E_B PF04042.16 RKO98129.1 - 3.2e-34 118.1 0.1 4e-34 117.8 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Metallophos_2 PF12850.7 RKO98129.1 - 0.086 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain VPS28 PF03997.12 RKO98130.1 - 2.3e-65 219.9 0.0 2.7e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 VPS28 protein Herpes_capsid PF06112.11 RKO98130.1 - 4 7.5 10.9 7.3 6.6 10.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein HEAT_2 PF13646.6 RKO98131.1 - 1.3e-09 38.3 9.2 0.00074 19.9 0.3 6.2 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 RKO98131.1 - 4e-08 32.9 15.1 0.081 13.2 0.1 6.8 6 0 0 6 6 6 4 HEAT repeat UBA PF00627.31 RKO98131.1 - 0.15 12.0 0.3 24 5.0 0.0 2.9 2 0 0 2 2 2 0 UBA/TS-N domain DUF4042 PF13251.6 RKO98131.1 - 7.6 6.2 14.6 2.7 7.7 0.0 5.0 6 1 0 6 6 6 0 Domain of unknown function (DUF4042) MutS_V PF00488.21 RKO98133.1 - 2.8e-55 187.3 0.0 6.7e-55 186.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 RKO98133.1 - 4.2e-24 85.8 2.3 9.9e-24 84.6 2.3 1.7 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 RKO98133.1 - 6.4e-12 45.9 0.1 2.1e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 RKO98133.1 - 1.5e-08 34.8 0.2 2.8e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_30 PF13604.6 RKO98133.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_27 PF13514.6 RKO98133.1 - 0.082 12.5 0.0 0.34 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 RKO98133.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_23 PF13476.6 RKO98133.1 - 0.13 12.8 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain Nic96 PF04097.14 RKO98134.1 - 4.7e-88 296.2 0.0 6.4e-88 295.8 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 AAA_23 PF13476.6 RKO98135.1 - 8.7e-15 55.8 0.0 1.4e-14 55.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 RKO98135.1 - 1.2e-07 31.4 0.0 1.9e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 RKO98135.1 - 9.1e-06 25.6 0.8 4.1e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_13 PF13166.6 RKO98135.1 - 0.0011 17.8 0.8 0.67 8.5 0.1 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RKO98135.1 - 0.0026 17.5 0.0 0.0066 16.2 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Atg14 PF10186.9 RKO98135.1 - 0.019 14.1 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 AAA_27 PF13514.6 RKO98135.1 - 0.03 13.9 0.5 0.18 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 RKO98135.1 - 0.038 13.3 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 RKO98135.1 - 0.058 13.9 2.1 1.2 9.7 0.8 2.4 2 1 0 2 2 2 0 ABC transporter ABC_tran_Xtn PF12848.7 RKO98135.1 - 0.087 12.9 0.3 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 ABC transporter DivIC PF04977.15 RKO98135.1 - 0.097 12.5 0.7 0.2 11.5 0.4 1.7 1 1 0 1 1 1 0 Septum formation initiator AAA_21 PF13304.6 RKO98135.1 - 0.56 10.0 4.8 0.48 10.2 2.6 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Proteasome PF00227.26 RKO98137.1 - 3.3e-58 196.3 0.0 4.6e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 RKO98137.1 - 1.1e-09 37.8 0.3 3.6e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature HMG_box PF00505.19 RKO98138.1 - 8.2e-18 64.6 0.1 1e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 RKO98138.1 - 3.6e-10 40.3 0.1 4.7e-10 39.9 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain Ank_4 PF13637.6 RKO98139.1 - 4e-05 24.1 0.0 0.085 13.5 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 RKO98139.1 - 0.00059 20.4 0.2 0.023 15.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 RKO98139.1 - 0.00087 19.6 0.1 15 6.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat DUF4228 PF14009.6 RKO98139.1 - 0.07 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Ank_5 PF13857.6 RKO98139.1 - 0.073 13.4 0.1 7 7.1 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF4832 PF16116.5 RKO98140.1 - 0.015 15.2 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4832) DUF4874 PF16173.5 RKO98140.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) DEAD PF00270.29 RKO98141.1 - 4.9e-28 98.1 0.0 1.3e-27 96.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 RKO98141.1 - 3.5e-21 75.5 0.0 5.8e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain ResIII PF04851.15 RKO98141.1 - 1.2e-13 51.5 0.0 2.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 RKO98141.1 - 2.2e-08 34.4 0.0 1.2e-07 32.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 RKO98141.1 - 1.2e-06 28.3 0.6 1e-05 25.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 RKO98141.1 - 3.9e-06 27.3 0.1 0.00045 20.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 RKO98141.1 - 0.0016 18.7 0.2 0.015 15.6 0.2 2.4 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 RKO98141.1 - 0.0045 16.1 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD-helicase PF00580.21 RKO98141.1 - 0.03 13.9 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SWI2_SNF2 PF18766.1 RKO98141.1 - 0.036 13.8 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase HORMA PF02301.18 RKO98142.1 - 5e-46 157.0 0.0 1e-45 156.0 0.0 1.5 2 0 0 2 2 2 1 HORMA domain Ribosomal_S7 PF00177.21 RKO98143.1 - 5.1e-36 123.6 0.4 6.7e-36 123.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DinI PF06183.13 RKO98143.1 - 0.083 13.2 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 DinI-like family ABC_tran PF00005.27 RKO98144.1 - 8.6e-48 162.3 0.0 1e-23 84.4 0.0 3.9 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.19 RKO98144.1 - 7.6e-17 61.5 0.5 4.1e-05 23.1 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 RKO98144.1 - 1.6e-15 57.7 2.3 0.0033 17.3 0.1 4.3 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 RKO98144.1 - 1.1e-08 35.3 0.1 0.012 15.8 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.6 RKO98144.1 - 3.2e-08 34.3 8.5 0.0083 16.7 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 RKO98144.1 - 8.5e-08 32.6 0.0 0.064 13.5 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_28 PF13521.6 RKO98144.1 - 2e-07 31.4 0.0 0.0041 17.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 RKO98144.1 - 7.5e-07 28.8 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 RKO98144.1 - 7.7e-07 29.7 0.4 0.096 13.1 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 RKO98144.1 - 1.1e-06 28.6 0.1 0.027 14.6 0.0 4.0 4 0 0 4 4 3 2 50S ribosome-binding GTPase AAA PF00004.29 RKO98144.1 - 4.2e-06 27.2 0.3 0.087 13.2 0.0 4.7 5 1 0 5 5 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RKO98144.1 - 1.1e-05 25.3 0.0 0.94 9.2 0.0 3.8 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 RKO98144.1 - 2.7e-05 24.1 0.0 0.011 15.7 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 RKO98144.1 - 3.2e-05 24.5 0.1 0.14 12.7 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 RKO98144.1 - 5.3e-05 23.1 0.1 1.5 8.5 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain RNA_helicase PF00910.22 RKO98144.1 - 0.00014 22.2 0.0 1.4 9.3 0.0 3.5 3 0 0 3 3 3 1 RNA helicase NACHT PF05729.12 RKO98144.1 - 0.00015 21.7 0.1 0.021 14.8 0.0 2.9 2 1 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 RKO98144.1 - 0.00044 20.0 0.0 1 9.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain Cnd1 PF12717.7 RKO98144.1 - 0.0012 18.9 0.7 0.012 15.6 0.1 2.6 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 ATPase_2 PF01637.18 RKO98144.1 - 0.0012 18.8 0.0 0.2 11.5 0.0 3.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea MeaB PF03308.16 RKO98144.1 - 0.0017 17.4 0.4 0.24 10.3 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Chromo PF00385.24 RKO98144.1 - 0.0017 18.2 0.3 0.005 16.7 0.0 2.0 2 0 0 2 2 1 1 Chromo (CHRromatin Organisation MOdifier) domain HEAT_EZ PF13513.6 RKO98144.1 - 0.0017 18.8 7.3 0.016 15.7 0.3 4.4 3 1 1 4 4 3 1 HEAT-like repeat AAA_7 PF12775.7 RKO98144.1 - 0.0022 17.6 0.0 0.57 9.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region HEAT PF02985.22 RKO98144.1 - 0.0026 17.9 2.7 0.014 15.6 0.0 3.7 3 0 0 3 3 1 1 HEAT repeat CLASP_N PF12348.8 RKO98144.1 - 0.0033 17.0 0.1 0.011 15.3 0.1 1.9 2 0 0 2 2 1 1 CLASP N terminal SbcCD_C PF13558.6 RKO98144.1 - 0.004 17.3 0.0 0.2 11.9 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 RKO98144.1 - 0.0055 16.7 0.0 0.86 9.6 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 RKO98144.1 - 0.0062 16.2 0.2 1.4 8.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 RKO98144.1 - 0.0066 15.7 0.0 0.56 9.4 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain TsaE PF02367.17 RKO98144.1 - 0.0069 16.4 0.0 2.4 8.2 0.0 3.0 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 RKO98144.1 - 0.0085 16.3 0.0 5.2 7.3 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 RKO98144.1 - 0.0085 15.7 0.1 1.4 8.5 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMS19_C PF12460.8 RKO98144.1 - 0.012 14.8 1.0 0.037 13.1 0.3 2.1 1 1 1 2 2 2 0 RNAPII transcription regulator C-terminal PduV-EutP PF10662.9 RKO98144.1 - 0.014 15.1 0.0 2.4 7.9 0.0 2.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Cytidylate_kin PF02224.18 RKO98144.1 - 0.016 14.9 0.0 4.7 6.9 0.0 3.0 2 1 0 2 2 2 0 Cytidylate kinase DUF1843 PF08898.10 RKO98144.1 - 0.016 15.7 0.9 0.098 13.2 0.9 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) G-alpha PF00503.20 RKO98144.1 - 0.019 14.2 0.1 6 5.9 0.1 2.6 2 0 0 2 2 2 0 G-protein alpha subunit 4HB PF17947.1 RKO98144.1 - 0.022 14.8 0.1 0.076 13.1 0.1 2.0 1 0 0 1 1 1 0 Four helical bundle domain DUF87 PF01935.17 RKO98144.1 - 0.026 14.6 0.2 11 6.0 0.0 3.4 3 0 0 3 3 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 RKO98144.1 - 0.027 14.3 0.0 5.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.6 RKO98144.1 - 0.033 14.5 0.1 53 4.1 0.0 3.8 4 0 0 4 4 3 0 AAA domain AAA_5 PF07728.14 RKO98144.1 - 0.038 14.0 0.0 5.5 7.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FAA_hydro_N_2 PF18288.1 RKO98144.1 - 0.06 13.8 0.5 2.9 8.4 0.0 3.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 AAA_17 PF13207.6 RKO98144.1 - 0.07 13.6 11.6 3 8.3 0.0 4.7 5 1 0 5 5 3 0 AAA domain NTPase_1 PF03266.15 RKO98144.1 - 0.071 13.0 0.1 19 5.1 0.0 3.5 3 0 0 3 3 3 0 NTPase HEAT_2 PF13646.6 RKO98144.1 - 0.1 13.0 4.2 1.7 9.1 0.1 3.6 2 2 2 4 4 3 0 HEAT repeats HBS1_N PF08938.10 RKO98144.1 - 0.17 12.2 3.5 13 6.1 0.1 3.6 3 0 0 3 3 2 0 HBS1 N-terminus TetR_C_31 PF17940.1 RKO98144.1 - 1 9.6 4.9 0.23 11.7 0.2 2.4 3 0 0 3 3 1 0 Tetracyclin repressor-like, C-terminal domain AAA_13 PF13166.6 RKO98144.1 - 1.2 7.7 0.0 1.2 7.7 0.0 3.7 5 0 0 5 5 4 0 AAA domain LIN37 PF15306.6 RKO98145.1 - 0.059 13.6 0.1 20 5.3 0.0 2.7 3 0 0 3 3 3 0 LIN37 Rhomboid PF01694.22 RKO98146.1 - 1.8e-31 109.2 14.8 1.8e-31 109.2 14.8 2.5 2 1 1 3 3 3 1 Rhomboid family DUF2070 PF09843.9 RKO98146.1 - 0.17 10.2 2.3 0.28 9.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) VKOR PF07884.14 RKO98146.1 - 4 7.6 10.7 0.82 9.9 5.3 2.7 2 1 0 2 2 2 0 Vitamin K epoxide reductase family Rad60-SLD PF11976.8 RKO98147.1 - 7.4e-22 77.0 0.2 8.8e-22 76.7 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 RKO98147.1 - 9.7e-11 41.3 0.2 1.1e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family SH3_1 PF00018.28 RKO98147.1 - 0.043 13.4 0.1 0.11 12.1 0.0 1.7 2 0 0 2 2 2 0 SH3 domain DUF3336 PF11815.8 RKO98149.1 - 2.5e-36 124.4 0.2 3.9e-36 123.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 RKO98149.1 - 1.3e-16 61.4 0.0 3.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase TAF1_subA PF14929.6 RKO98149.1 - 0.05 13.0 0.1 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A Tctex-1 PF03645.13 RKO98150.1 - 6.4e-31 106.6 0.5 7.4e-31 106.5 0.5 1.0 1 0 0 1 1 1 1 Tctex-1 family Glycogen_syn PF05693.13 RKO98151.1 - 0 1066.7 0.0 0 1066.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 RKO98151.1 - 5.1e-07 29.4 0.0 0.00026 20.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 RKO98151.1 - 1.2e-06 28.4 0.1 7.5e-06 25.8 0.1 2.2 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 RKO98151.1 - 5.9e-06 26.7 0.0 0.0057 17.1 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 RKO98151.1 - 2e-05 25.1 0.1 5.3e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 RKO98151.1 - 0.0003 20.9 0.1 0.00082 19.4 0.1 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Pkinase PF00069.25 RKO98152.1 - 3.1e-57 194.0 0.0 2.3e-56 191.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 RKO98152.1 - 5.3e-27 94.7 0.1 7.9e-21 74.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 RKO98152.1 - 4.4e-05 23.5 0.8 0.0013 18.7 0.0 2.8 1 1 2 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 RKO98152.1 - 0.00072 19.0 0.0 0.0038 16.6 0.0 2.1 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 RKO98152.1 - 0.008 15.5 0.0 0.023 14.1 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 RKO98152.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 RKO98152.1 - 0.022 13.9 0.0 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 Seadornavirus VP7 Pkinase_C PF00433.24 RKO98152.1 - 0.088 13.5 0.2 0.4 11.4 0.1 2.2 2 0 0 2 2 2 0 Protein kinase C terminal domain S1-P1_nuclease PF02265.16 RKO98153.1 - 7.4e-55 186.5 0.4 8.4e-55 186.3 0.4 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease Hc1 PF07432.13 RKO98154.1 - 0.47 10.8 19.1 0.75 10.2 19.1 1.3 1 0 0 1 1 1 0 Histone H1-like protein Hc1 RabGAP-TBC PF00566.18 RKO98156.1 - 2.1e-23 83.1 0.4 1.3e-22 80.5 0.4 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain NuDC PF16273.5 RKO98157.1 - 0.028 14.9 1.4 0.028 14.9 1.4 3.8 4 0 0 4 4 4 0 Nuclear distribution C domain Lipase_GDSL_2 PF13472.6 RKO98158.1 - 5.6e-13 49.7 2.5 3.2e-12 47.2 1.4 2.6 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 RKO98158.1 - 8e-05 22.7 0.0 0.00019 21.5 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase PIG-X PF08320.12 RKO98159.1 - 1.2e-12 48.2 1.3 1.4e-11 44.7 1.3 2.3 1 1 0 1 1 1 1 PIG-X / PBN1 TFIIS_C PF01096.18 RKO98161.1 - 2.2e-19 69.0 3.1 2.2e-19 69.0 3.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 RKO98161.1 - 2.4e-07 30.5 1.6 2.4e-07 30.5 1.6 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 RKO98161.1 - 0.00012 22.0 7.5 0.023 14.7 1.3 2.6 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 RKO98161.1 - 0.0015 18.2 1.3 0.0015 18.2 1.3 1.8 2 1 0 2 2 1 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_9 PF14369.6 RKO98161.1 - 0.16 12.2 8.8 2.1 8.7 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon zf-ribbon_3 PF13248.6 RKO98161.1 - 0.24 10.8 0.3 0.24 10.8 0.3 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.13 RKO98161.1 - 0.46 10.6 8.7 0.41 10.7 3.8 2.6 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_11 PF16622.5 RKO98161.1 - 0.54 10.1 0.1 0.54 10.1 0.1 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-ZPR1 PF03367.13 RKO98161.1 - 0.74 9.7 7.0 0.14 12.1 0.8 2.2 2 1 0 2 2 2 0 ZPR1 zinc-finger domain zinc_ribbon_4 PF13717.6 RKO98161.1 - 1.4 8.9 14.1 12 5.9 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain IBR PF01485.21 RKO98161.1 - 2 8.7 12.0 6.9e+02 0.6 12.0 2.9 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain PI3_PI4_kinase PF00454.27 RKO98162.1 - 9.3e-33 114.1 0.0 4.9e-32 111.7 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 RKO98162.1 - 9.7e-06 25.1 0.0 1.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DDE_Tnp_ISAZ013 PF07592.11 RKO98162.1 - 0.0017 17.4 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain EMG1 PF03587.14 RKO98163.1 - 2.8e-80 268.5 0.0 3.3e-80 268.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase WD40 PF00400.32 RKO98164.1 - 3.2e-15 56.2 7.3 0.0004 21.1 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98164.1 - 0.0011 19.2 0.0 7.6 6.9 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain UcrQ PF02939.16 RKO98165.1 - 1.3e-10 41.0 0.0 1.4e-10 40.9 0.0 1.0 1 0 0 1 1 1 1 UcrQ family LMBR1 PF04791.16 RKO98166.1 - 2.6e-38 132.2 24.9 8.4e-26 90.9 0.3 2.0 1 1 1 2 2 2 2 LMBR1-like membrane protein GPHR_N PF12537.8 RKO98166.1 - 0.25 11.4 1.6 2.4 8.3 0.0 3.0 3 0 0 3 3 3 0 The Golgi pH Regulator (GPHR) Family N-terminal Ig_mannosidase PF17753.1 RKO98167.1 - 2.3e-13 49.7 0.0 5e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 RKO98167.1 - 1.6e-07 30.7 0.4 5.4e-07 29.0 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Mannosidase_ig PF17786.1 RKO98167.1 - 4.7e-05 23.9 0.6 0.00024 21.7 0.3 2.3 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_GlcNase PF18368.1 RKO98167.1 - 0.0002 21.5 0.3 0.0053 16.9 0.0 2.6 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2_N PF02837.18 RKO98167.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain AAA PF00004.29 RKO98168.1 - 1.8e-43 148.1 0.0 3.8e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 RKO98168.1 - 4.2e-11 42.5 0.1 1.2e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 RKO98168.1 - 3.6e-07 30.5 0.0 1.1e-06 28.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 RKO98168.1 - 6.2e-07 29.3 0.6 1.6e-06 27.9 0.6 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 RKO98168.1 - 1.8e-06 28.0 0.0 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 RKO98168.1 - 2.7e-06 27.9 0.1 4.6e-05 23.9 0.1 2.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 RKO98168.1 - 6.4e-05 23.2 0.1 0.0093 16.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 RKO98168.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 RKO98168.1 - 0.0012 18.1 0.0 0.0028 16.9 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 RKO98168.1 - 0.0013 19.3 0.0 0.022 15.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 RKO98168.1 - 0.0014 18.8 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 RKO98168.1 - 0.0025 17.6 0.0 0.0054 16.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 RKO98168.1 - 0.003 17.0 0.3 0.021 14.2 0.1 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 RKO98168.1 - 0.0059 16.5 0.0 0.018 14.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 RKO98168.1 - 0.0092 16.2 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 RKO98168.1 - 0.013 15.9 0.2 0.7 10.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 RKO98168.1 - 0.013 15.2 0.0 0.1 12.3 0.0 2.2 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 RKO98168.1 - 0.018 14.5 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 RKO98168.1 - 0.023 14.7 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 RKO98168.1 - 0.024 14.3 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 RKO98168.1 - 0.024 14.0 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 KaiC DUF815 PF05673.13 RKO98168.1 - 0.029 13.5 0.2 0.1 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 RKO98168.1 - 0.038 13.5 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 RKO98168.1 - 0.039 14.3 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF2072 PF09845.9 RKO98168.1 - 0.042 14.1 0.1 0.084 13.1 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein AAA_14 PF13173.6 RKO98168.1 - 0.053 13.6 0.0 0.094 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF4618 PF15397.6 RKO98168.1 - 0.061 12.7 2.2 0.15 11.4 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Parvo_NS1 PF01057.17 RKO98168.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 RKO98168.1 - 0.069 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 RKO98168.1 - 0.083 12.2 1.1 0.2 10.9 0.0 2.2 3 0 0 3 3 2 0 Zeta toxin APG6_N PF17675.1 RKO98168.1 - 0.1 13.1 2.7 0.21 12.1 2.7 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_11 PF13086.6 RKO98168.1 - 0.11 12.2 0.2 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 RKO98168.1 - 0.13 12.1 0.0 0.64 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain SlyX PF04102.12 RKO98168.1 - 0.21 12.3 2.7 0.9 10.2 2.7 2.1 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 RKO98168.1 - 2.3 8.0 6.0 5.7 6.8 6.0 1.6 1 0 0 1 1 1 0 Septum formation initiator cobW PF02492.19 RKO98170.1 - 4.9e-45 153.3 0.0 5.7e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 RKO98170.1 - 0.0026 17.7 0.1 0.011 15.6 0.1 1.9 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.23 RKO98170.1 - 0.0036 17.4 0.0 0.0051 16.9 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 RKO98170.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.6 RKO98170.1 - 0.012 16.2 0.0 0.019 15.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 RKO98170.1 - 0.024 15.0 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 RKO98170.1 - 0.025 13.5 0.2 0.035 13.0 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 RKO98170.1 - 0.035 14.3 0.1 0.06 13.6 0.1 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TsaE PF02367.17 RKO98170.1 - 0.036 14.1 0.1 0.064 13.3 0.1 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 RKO98170.1 - 0.07 13.4 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 RKO98170.1 - 0.073 12.8 0.2 0.16 11.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 RKO98170.1 - 0.084 12.8 0.3 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.18 RKO98170.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 RKO98170.1 - 0.16 12.1 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain CSD PF00313.22 RKO98171.1 - 2.2e-18 65.8 0.1 3.6e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 RKO98171.1 - 0.13 12.0 0.1 0.38 10.5 0.1 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain WD40 PF00400.32 RKO98172.1 - 1.8e-07 31.7 3.2 0.055 14.4 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 RKO98172.1 - 2.5e-05 24.5 0.0 0.84 10.0 0.0 4.5 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain V-ATPase_G PF03179.15 RKO98172.1 - 0.049 14.2 0.0 0.098 13.2 0.0 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit EMP70 PF02990.16 RKO98173.1 - 1.9e-184 614.2 6.9 1.9e-184 614.2 6.9 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 Phage_holin_3_6 PF07332.11 RKO98173.1 - 0.14 12.2 0.0 0.14 12.2 0.0 5.2 3 2 1 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III PigN PF04987.14 RKO98174.1 - 2.3e-115 386.1 24.9 3e-115 385.7 24.9 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 RKO98174.1 - 1.3e-13 51.3 2.0 9.4e-13 48.5 2.0 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 RKO98174.1 - 1.9e-06 27.5 0.2 4e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 RKO98174.1 - 0.00022 20.7 0.1 0.00038 19.9 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily zf-H2C2_2 PF13465.6 RKO98175.1 - 5.8e-11 42.3 14.6 1.2e-05 25.5 2.9 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 RKO98175.1 - 8.5e-11 41.7 19.9 0.00043 20.6 4.8 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 RKO98175.1 - 5.4e-08 33.0 19.4 0.0011 19.6 4.6 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-LYAR PF08790.11 RKO98175.1 - 0.0069 16.3 6.0 0.015 15.2 0.2 2.9 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 RKO98175.1 - 0.017 15.6 7.9 0.72 10.3 0.7 2.9 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger IBR PF01485.21 RKO98175.1 - 0.034 14.4 4.6 0.39 11.0 4.6 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2H2_6 PF13912.6 RKO98175.1 - 0.052 13.6 12.2 0.11 12.6 0.3 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 RKO98175.1 - 0.067 13.5 2.0 0.39 11.1 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 RKO98175.1 - 0.11 12.1 1.9 13 5.5 0.8 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger FYDLN_acid PF09538.10 RKO98175.1 - 0.13 12.9 1.4 2.6 8.8 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (FYDLN_acid) zf-H2C2_5 PF13909.6 RKO98175.1 - 0.38 10.6 14.7 4.5 7.1 6.8 3.5 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 RKO98175.1 - 0.88 9.9 9.3 0.074 13.4 2.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Zn_Tnp_IS1595 PF12760.7 RKO98175.1 - 1.4 9.0 11.7 0.73 9.9 9.4 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf_C2H2_ZHX PF18387.1 RKO98175.1 - 2.3 7.9 7.4 4.3 7.1 2.9 2.5 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_9 PF14369.6 RKO98175.1 - 3.4 8.0 13.9 1.2 9.5 0.5 3.2 3 0 0 3 3 3 0 zinc-ribbon OTU PF02338.19 RKO98176.1 - 4.3e-05 24.0 0.0 7.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Ribosomal_S11 PF00411.19 RKO98178.1 - 2.3e-47 160.0 1.3 2.8e-47 159.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 RKO98178.1 - 0.022 15.0 0.0 0.038 14.2 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) BKACE PF05853.12 RKO98178.1 - 0.032 13.5 0.1 0.041 13.2 0.1 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Yae1_N PF09811.9 RKO98179.1 - 1.7e-09 37.2 0.8 2.3e-09 36.8 0.8 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal RhoGEF PF00621.20 RKO98180.1 - 2e-29 103.1 3.1 4.4e-29 102.0 3.1 1.6 1 0 0 1 1 1 1 RhoGEF domain RA PF00788.23 RKO98180.1 - 3.7e-07 30.7 0.1 7.9e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain HR1 PF02185.16 RKO98180.1 - 6.2e-07 29.4 5.3 3e-06 27.3 2.5 2.8 2 0 0 2 2 2 1 Hr1 repeat C1_1 PF00130.22 RKO98180.1 - 0.0013 18.5 9.4 0.0025 17.7 9.4 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PH PF00169.29 RKO98180.1 - 0.0038 17.7 0.0 0.019 15.5 0.0 2.2 1 0 0 1 1 1 1 PH domain JAKMIP_CC3 PF16034.5 RKO98180.1 - 0.036 14.0 0.2 0.24 11.3 0.2 2.4 1 0 0 1 1 1 0 JAKMIP CC3 domain Uds1 PF15456.6 RKO98180.1 - 0.24 11.6 6.4 0.13 12.4 2.5 2.5 2 0 0 2 2 2 0 Up-regulated During Septation CpxA_peri PF16527.5 RKO98180.1 - 9.4 6.6 5.7 7.5 6.9 0.6 2.9 3 0 0 3 3 3 0 Two-component sensor protein CpxA, periplasmic domain MORN PF02493.20 RKO98181.1 - 1.3e-36 122.3 24.4 9.4e-09 34.7 2.5 6.4 6 0 0 6 6 6 6 MORN repeat Rib PF08428.10 RKO98181.1 - 0.035 14.1 0.1 0.6 10.1 0.0 2.3 2 0 0 2 2 2 0 Rib/alpha-like repeat Ax_dynein_light PF10211.9 RKO98182.1 - 7.2e-80 267.4 13.9 8.3e-80 267.2 13.9 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Collectrin PF16959.5 RKO98182.1 - 0.011 15.5 0.2 0.018 14.8 0.2 1.3 1 0 0 1 1 1 0 Renal amino acid transporter YlbD_coat PF14071.6 RKO98182.1 - 0.32 11.3 2.9 1.4 9.2 0.4 2.2 2 0 0 2 2 2 0 Putative coat protein PRKG1_interact PF15898.5 RKO98182.1 - 0.82 10.6 9.7 0.35 11.8 6.1 2.0 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Spc24 PF08286.11 RKO98182.1 - 1.6 9.0 5.5 1.1 9.5 3.3 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2570 PF10828.8 RKO98182.1 - 1.9 8.4 8.3 0.23 11.3 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) MT PF12777.7 RKO98183.1 - 2.2e-160 533.4 14.1 2.6e-160 533.1 12.1 2.2 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor DHC_N1 PF08385.12 RKO98183.1 - 3.2e-160 534.5 0.9 9.9e-158 526.3 0.1 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 RKO98183.1 - 6.5e-155 515.0 0.4 3.2e-152 506.2 0.0 3.4 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 RKO98183.1 - 2.3e-123 412.2 3.3 2.3e-123 412.2 3.3 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 RKO98183.1 - 2.8e-98 329.0 1.7 5.1e-98 328.1 0.1 2.5 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 RKO98183.1 - 1.5e-97 326.0 0.1 2.6e-96 321.9 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 RKO98183.1 - 2e-83 278.8 0.7 2e-83 278.8 0.7 2.1 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 RKO98183.1 - 2.3e-73 245.6 0.1 2.9e-66 222.4 0.0 3.9 4 0 0 4 4 3 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 RKO98183.1 - 1.1e-51 174.9 0.0 1.3e-49 168.1 0.0 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 RKO98183.1 - 1.1e-37 128.7 0.0 3.5e-36 123.9 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 RKO98183.1 - 1.7e-36 124.4 0.3 9.1e-36 122.1 0.3 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 RKO98183.1 - 9.1e-26 90.5 0.0 7e-14 52.0 0.0 6.3 6 1 0 6 6 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 RKO98183.1 - 1.7e-21 76.7 0.1 5.3e-21 75.1 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 RKO98183.1 - 1.3e-10 41.9 2.4 0.0048 17.3 0.0 6.3 6 1 1 7 7 5 2 AAA ATPase domain AAA_22 PF13401.6 RKO98183.1 - 1.3e-07 32.0 0.0 0.36 11.1 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 RKO98183.1 - 3.7e-06 27.4 0.2 0.028 14.8 0.0 4.8 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 RKO98183.1 - 5.6e-06 26.2 0.0 4.5 6.9 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 RKO98183.1 - 0.0006 20.4 0.9 0.48 11.0 0.0 4.3 4 0 0 4 4 3 1 AAA domain Sigma54_activat PF00158.26 RKO98183.1 - 0.00089 19.0 0.0 2.2 7.9 0.0 3.9 4 0 0 4 4 4 1 Sigma-54 interaction domain AAA_19 PF13245.6 RKO98183.1 - 0.0011 19.3 4.2 3.9 7.8 0.0 4.3 4 0 0 4 4 3 1 AAA domain RNA_helicase PF00910.22 RKO98183.1 - 0.0021 18.4 0.1 17 5.8 0.1 3.9 3 0 0 3 3 3 0 RNA helicase ABC_tran PF00005.27 RKO98183.1 - 0.0029 18.1 1.0 2.3 8.7 0.0 4.3 4 0 0 4 4 3 1 ABC transporter Sigma54_activ_2 PF14532.6 RKO98183.1 - 0.0031 17.6 0.1 4.2 7.5 0.0 3.6 3 0 0 3 3 2 1 Sigma-54 interaction domain NACHT PF05729.12 RKO98183.1 - 0.0073 16.2 0.1 0.94 9.4 0.0 3.5 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 RKO98183.1 - 0.011 15.8 0.9 7.5 6.6 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 RKO98183.1 - 0.027 13.7 0.0 0.61 9.2 0.0 2.7 2 0 0 2 2 2 0 PIF1-like helicase AAA_29 PF13555.6 RKO98183.1 - 0.031 14.0 0.3 15 5.4 0.0 3.7 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_33 PF13671.6 RKO98183.1 - 0.033 14.3 0.2 61 3.8 0.0 4.3 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 RKO98183.1 - 0.04 13.9 0.5 2.9 7.8 0.0 3.8 4 0 0 4 4 3 0 Rad17 P-loop domain Mg_chelatase PF01078.21 RKO98183.1 - 0.048 13.0 0.1 13 5.1 0.0 3.9 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 RKO98183.1 - 0.068 12.3 0.0 33 3.5 0.0 3.8 4 0 0 4 4 3 0 Protein of unknown function (DUF815) CbiA PF01656.23 RKO98183.1 - 0.16 12.0 0.0 8.6 6.4 0.0 3.3 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RTA1 PF04479.13 RKO98183.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 RTA1 like protein IFT46_B_C PF12317.8 RKO98183.1 - 1.1 8.9 7.6 2.9 7.6 1.9 2.8 2 0 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal GreA_GreB_N PF03449.15 RKO98183.1 - 3.3 7.9 7.1 0.53 10.5 0.7 3.2 2 0 0 2 2 1 0 Transcription elongation factor, N-terminal B9-C2 PF07162.11 RKO98185.1 - 2.9e-26 92.7 0.1 5.6e-26 91.7 0.0 1.5 2 0 0 2 2 2 1 Ciliary basal body-associated, B9 protein Y_phosphatase2 PF03162.13 RKO98186.1 - 7.8e-55 184.9 0.0 8.9e-55 184.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 RKO98186.1 - 0.00024 21.1 0.0 0.0019 18.2 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 RKO98186.1 - 0.036 13.6 0.0 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase ArfGap PF01412.18 RKO98187.1 - 2e-32 111.7 0.1 6.6e-32 110.0 0.1 1.9 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 RKO98187.1 - 3.7e-16 59.6 12.1 6.1e-16 58.8 12.1 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 RKO98187.1 - 1e-07 32.4 0.0 2.1e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 PH domain Trypan_PARP PF05887.11 RKO98188.1 - 0.025 14.6 2.7 0.05 13.6 2.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Caulochytrium_protostelioides-Caupr_SCcomb/GCA_003615035.1_Caupr_SCcomb_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Caulochytrium_protostelioides-Caupr_SCcomb/GCA_003615035.1_Caupr_SCcomb_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Caulochytrium_protostelioides-Caupr_SCcomb/GCA_003615035.1_Caupr_SCcomb_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Chytridiomycota/Caulochytrium_protostelioides-Caupr_SCcomb/GCA_003615035.1_Caupr_SCcomb_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 16:40:41 2019 # [ok]